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Sample records for regularize function efeito

  1. Regularity and approximability of electronic wave functions

    CERN Document Server

    Yserentant, Harry

    2010-01-01

    The electronic Schrödinger equation describes the motion of N-electrons under Coulomb interaction forces in a field of clamped nuclei. The solutions of this equation, the electronic wave functions, depend on 3N variables, with three spatial dimensions for each electron. Approximating these solutions is thus inordinately challenging, and it is generally believed that a reduction to simplified models, such as those of the Hartree-Fock method or density functional theory, is the only tenable approach. This book seeks to show readers that this conventional wisdom need not be ironclad: the regularity of the solutions, which increases with the number of electrons, the decay behavior of their mixed derivatives, and the antisymmetry enforced by the Pauli principle contribute properties that allow these functions to be approximated with an order of complexity which comes arbitrarily close to that for a system of one or two electrons. The text is accessible to a mathematical audience at the beginning graduate level as...

  2. On a correspondence between regular and non-regular operator monotone functions

    DEFF Research Database (Denmark)

    Gibilisco, P.; Hansen, Frank; Isola, T.

    2009-01-01

    We prove the existence of a bijection between the regular and the non-regular operator monotone functions satisfying a certain functional equation. As an application we give a new proof of the operator monotonicity of certain functions related to the Wigner-Yanase-Dyson skew information....

  3. On certain inequalities for some regular functions in |z|<1

    Directory of Open Access Journals (Sweden)

    Milutin Obradovic

    1985-01-01

    Full Text Available In this paper we give some inequalities for regular functions f(z=z+a2z2+… in |z|<1 especially for starlike and convex functions of order α, 0≤α<1, To some extent those inequalities are the generalisations and improvements of the previous results given by Bernardi [1]. Some interesting consequences are given, too.

  4. A Subordination Principle on Wright Functions and Regularized Resolvent Families

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    Luciano Abadias

    2015-01-01

    Full Text Available We obtain a vector-valued subordination principle for gα,gβ-regularized resolvent families which unified and improves various previous results in the literature. As a consequence, we establish new relations between solutions of different fractional Cauchy problems. To do that, we consider scaled Wright functions which are related to Mittag-Leffler functions, the fractional calculus, and stable Lévy processes. We study some interesting properties of these functions such as subordination (in the sense of Bochner, convolution properties, and their Laplace transforms. Finally we present some examples where we apply these results.

  5. Efeito da prática regular de atividade física no desempenho motor em idosos Effect of regular practice of physical activity in motor performance in the elderly

    Directory of Open Access Journals (Sweden)

    Paula Cristina dos Santos Rodrigues

    2010-12-01

    Full Text Available Os efeitos do envelhecimento contribuem para uma maior lentidão no processamento da informação, nomeadamente ao nível do tratamento da informação sensorial, decisão e programação dos movimentos. O presente estudo investigou o tempo de reação simples e o tempo de antecipação-coincidência, em idosos praticantes e não praticantes de atividade física. Constituíram a amostra 66 idosos de ambos os sexos com idade cronológica entre os 65 e os 89 anos (M = 74,3; SD = 6,0 anos, dos quais 34 eram praticantes de atividade física regular e 32 não praticantes de atividade física regular. Os instrumentos utilizados foram o "Multi-Choice Reaction Time Apparatus" para avaliar o tempo de reação simples (TRS e o "Bassin Anticipation Timer" para avaliar a antecipação-coincidência (AC. Estas capacidades são relevantes no bem-estar e funcionalidade da população mais envelhecida. Cada participante realizou com a mão preferida um total de seis tentativas na tarefa de TRS e 20 tentativas na tarefa de AC. Os resultados revelaram que o grupo de praticantes de atividade física demonstrou desempenhos superiores tanto na tarefa de TRS como na tarefa de AC. O sexo foi fator influente apenas no grupo de praticantes no desempenho das duas tarefas, sendo os homens mais rápidos e precisos do que as mulheres. Um processamento da informação mais rápido nos homens pode estar na base destes resultados. Como as duas capacidades avaliadas neste estudo constituem uma expressão da integridade funcional do sistema nervoso central, os resultados sugerem que a prática de atividades motoras sistemáticas pode retardar e ser um importante protetor contra os efeitos de envelhecimento nos processos perceptivo-motores inerentes a este tipo de tarefas.The slowing down in information processing, particularly at the level of sensory information, decision and movement programming in elderly is a consequence of aging. The present study investigated simple

  6. Partial Regularity for Holonomic Minimisers of Quasiconvex Functionals

    Science.gov (United States)

    Hopper, Christopher P.

    2016-10-01

    We prove partial regularity for local minimisers of certain strictly quasiconvex integral functionals, over a class of Sobolev mappings into a compact Riemannian manifold, to which such mappings are said to be holonomically constrained. Our approach uses the lifting of Sobolev mappings to the universal covering space, the connectedness of the covering space, an application of Ekeland's variational principle and a certain tangential A-harmonic approximation lemma obtained directly via a Lipschitz approximation argument. This allows regularity to be established directly on the level of the gradient. Several applications to variational problems in condensed matter physics with broken symmetries are also discussed, in particular those concerning the superfluidity of liquid helium-3 and nematic liquid crystals.

  7. A regularization of the Hartle–Hawking wave function

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    Nataliya N. Gorobey

    2017-06-01

    Full Text Available The paper puts forward a modification of the no-boundary Hartle–Hawking wave function in which, in the general case, the Euclidean functional integral can be described by an inhomogeneous universe. The regularization of this integral is achieved in arbitrary canonical calibration by abandoning integration over the lapse and shift functions. This makes it possible to ‘correct’ the sign of the Euclidean action corresponding to the scale factor of geometry. An additional time parameter associated with the canonical calibration condition then emerges. An additional condition for the stationary state of the wave function's phase after returning to the Lorentzian signature, serving as the quantum equivalent of the classical principle of the least action, was used to find this time parameter. We have substantiated the interpretation of the modified wave function as the amplitude of the universe's birth from ‘nothing’ with the additional parameter as the time of this process. A homogeneous model of the universe with a conformally invariant scalar field has been considered. In this case, two variants of the no-boundary wave function which are solutions of the Wheeler–DeWitt equation have been found.

  8. Total Variation Regularization for Functions with Values in a Manifold

    KAUST Repository

    Lellmann, Jan

    2013-12-01

    While total variation is among the most popular regularizers for variational problems, its extension to functions with values in a manifold is an open problem. In this paper, we propose the first algorithm to solve such problems which applies to arbitrary Riemannian manifolds. The key idea is to reformulate the variational problem as a multilabel optimization problem with an infinite number of labels. This leads to a hard optimization problem which can be approximately solved using convex relaxation techniques. The framework can be easily adapted to different manifolds including spheres and three-dimensional rotations, and allows to obtain accurate solutions even with a relatively coarse discretization. With numerous examples we demonstrate that the proposed framework can be applied to variational models that incorporate chromaticity values, normal fields, or camera trajectories. © 2013 IEEE.

  9. Regular Football Practice Improves Autonomic Cardiac Function in Male Children

    Science.gov (United States)

    Fernandes, Luis; Oliveira, Jose; Soares-Miranda, Luisa; Rebelo, Antonio; Brito, Joao

    2015-01-01

    Background: The role of the autonomic nervous system (ANS) in the cardiovascular regulation is of primal importance. Since it has been associated with adverse conditions such as cardiac arrhythmias, sudden death, sleep disorders, hypertension and obesity. Objectives: The present study aimed to investigate the impact of recreational football practice on the autonomic cardiac function of male children, as measured by heart rate variability. Patients and Methods: Forty-seven male children aged 9 - 12 years were selected according to their engagement with football oriented practice outside school context. The children were divided into a football group (FG; n = 22) and a control group (CG; n = 25). The FG had regular football practices, with 2 weekly training sessions and occasional weekend matches. The CG was not engaged with any physical activity other than complementary school-based physical education classes. Data from physical activity, physical fitness, and heart rate variability measured in time and frequency domains were obtained. Results: The anthropometric and body composition characteristics were similar in both groups (P > 0.05). The groups were also similar in time spent daily on moderate-to-vigorous physical activities (FG vs. CG: 114 ± 64 vs. 87 ± 55 minutes; P > 0.05). However, the FG performed better (P football practice presented enhanced physical fitness and autonomic function, by increasing vagal tone at rest. PMID:26448848

  10. Regularity of Functions on the Reduced Quaternion Field in Clifford Analysis

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    Ji Eun Kim

    2014-01-01

    Full Text Available We define a new hypercomplex structure of ℝ3 and a regular function with values in that structure. From the properties of regular functions, we research the exponential function on the reduced quaternion field and represent the corresponding Cauchy-Riemann equations in hypercomplex structures of ℝ3.

  11. Regularities of socially significant functions formation in pupils

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    Hrebniak N.P.

    2016-05-01

    Full Text Available The article focused on the results of carried out research of the functional state of the pupils’ organism in a process of edu­cational activity. It has been shown that formative influence of activity is manifested on the different levels of develop­ment of socially important functions: the actual developmental zone (priority development of indicators, which have the main significance in the activity and the proximal developmental zone (tendency of activation of the key functions.

  12. A Regularity Lemma and Low-Weight Approximators for Low-Degree Polynomial Threshold Functions

    OpenAIRE

    Diakonikolas, Ilias; Servedio, Rocco A.; Tan, Li-Yang; Wan, Andrew

    2014-01-01

    We give a "regularity lemma" for degree-d polynomial threshold functions (PTFs) over the Boolean cube {−1,1}n. Roughly speaking, this result shows that every degree-d PTF can be decomposed into a constant number of subfunctions such that almost all of the subfunctions are close to being regular PTFs. Here a "regular" PTF is a PTF sign(p(x)) where the influence of each variable on the polynomial p(x) is a small fraction of the total influence of p.As an application of this regularity lemma, we...

  13. Improved Mumford-Shah Functional for Coupled Edge-Preserving Regularization and Image Segmentation

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    Hongmei Zhang

    2006-01-01

    Full Text Available An improved Mumford-Shah functional for coupled edge-preserving regularization and image segmentation is presented. A nonlinear smooth constraint function is introduced that can induce edge-preserving regularization thus also facilitate the coupled image segmentation. The formulation of the functional is considered from the level set perspective, so that explicit boundary contours and edge-preserving regularization are both addressed naturally. To reduce computational cost, a modified additive operator splitting (AOS algorithm is developed to address diffusion equations defined on irregular domains and multi-initial scheme is used to speed up the convergence rate. Experimental results by our approach are provided and compared with that of Mumford-Shah functional and other edge-preserving approach, and the results show the effectiveness of the proposed method.

  14. Kernel-Regularized ICA for Computing Functional Topography from Resting-state fMRI.

    Science.gov (United States)

    Wang, Junyan; Shi, Yonggang

    2017-09-01

    Topographic regularity is a fundamental property in brain connectivity. In this work, we present a novel method for studying topographic regularity of functional connectivity based on resting-state fMRI (rfMRI), which is widely available and easy to acquire in large-scale studies. The main idea in our method is the incorporation of topographically regular structural connectivity for independent component analysis (ICA). This is enabled by the recent development of novel tractography and tract filtering algorithms that can generate highly organized fiber bundles connecting different brain regions. By leveraging these cutting-edge tractography algorithms, here we develop a kernel-regularized ICA method for the extraction of functional topography with rfMRI signals. In our experiments, we use rfMRI scans of 35 unrelated, right-handed subjects from the Human Connectome Project (HCP) to study the functional topography of the motor cortex. We first demonstrate that our method can generate functional connectivity maps with more regular topography than conventional group ICA. We also show that the components extracted by our algorithm are able to capture co-activation patterns that respect the organized topography of the motor cortex across the hemisphere. Finally, we show that our method achieves improved reproducibility as compared to conventional group ICA.

  15. Combined function specification-regularization procedure for solution of inverse heat conduction problem

    Science.gov (United States)

    Beck, J. V.; Murio, D. A.

    1984-01-01

    The inverse heat conduction problem involves the calculation of surface heat flux and/or temperature histories from transient, measured temperatures inside solids. This paper proposes and investigates a new combined procedure that is based on two different methods. One of these methods is the sequential function specification method which was originally proposed by Beck. The other method is the regularization method which has been used by Tikhonov and others. The combined method uses the sequential feature of the function specification method and the special function that is minimized in the regularization method. A test case is investigated of a semi-infinite body exposed to a heat flux that is initially zero, has a step increase and then drops to zero. A wide range of parameters is investigated. The combined procedure is much more computationally efficient than the usual regularization procedure when all the flux components are found simultaneously and yet the calculated values found by combined method are little different.

  16. Zeta Function Regularization in Casimir Effect Calculations and J. S. Dowker's Contribution

    Science.gov (United States)

    Elizalde, Emilio

    2012-07-01

    A summary of relevant contributions, ordered in time, to the subject of operator zeta functions and their application to physical issues is provided. The description ends with the seminal contributions of Stephen Hawking and Stuart Dowker and collaborators, considered by many authors as the actual starting point of the introduction of zeta function regularization methods in theoretical physics, in particular, for quantum vacuum fluctuation and Casimir effect calculations. After recalling a number of the strengths of this powerful and elegant method, some of its limitations are discussed. Finally, recent results of the so called operator regularization procedure are presented.

  17. On rarely generalized regular fuzzy continuous functions in fuzzy topological spaces

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    Appachi Vadivel

    2016-11-01

    Full Text Available In this paper, we introduce the concept of rarely generalized regular fuzzy continuous functions in the sense of A.P. Sostak's and Ramadan is introduced. Some interesting properties and characterizations of them are investigated. Also, some applications to fuzzy compact spaces are established.

  18. The Regularity of Functions on Dual Split Quaternions in Clifford Analysis

    Directory of Open Access Journals (Sweden)

    Ji Eun Kim

    2014-01-01

    Full Text Available This paper shows some properties of dual split quaternion numbers and expressions of power series in dual split quaternions and provides differential operators in dual split quaternions and a dual split regular function on Ω⊂ℂ2×ℂ2 that has a dual split Cauchy-Riemann system in dual split quaternions.

  19. Existence and regularity of local solutions to partial neutral functional differential equations with infinite delay

    OpenAIRE

    Hassane Bouzahir

    2006-01-01

    In this paper, we establish results concerning, existence, uniqueness, global continuation, and regularity of integral solutions to some partial neutral functional differential equations with infinite delay. These equations find their origin in the description of heat flow models, viscoelastic and thermoviscoelastic materials, and lossless transmission lines models; see for example [15] and [38].

  20. Existence and regularity of local solutions to partial neutral functional differential equations with infinite delay

    Directory of Open Access Journals (Sweden)

    Hassane Bouzahir

    2006-08-01

    Full Text Available In this paper, we establish results concerning, existence, uniqueness, global continuation, and regularity of integral solutions to some partial neutral functional differential equations with infinite delay. These equations find their origin in the description of heat flow models, viscoelastic and thermoviscoelastic materials, and lossless transmission lines models; see for example [15] and [38].

  1. Zeta functions and regularized determinants related to the Selberg trace formula

    DEFF Research Database (Denmark)

    Momeni, Arash; Venkov, Alexei

    For a general Fuchsian group of the first kind with an arbitrary unitary representation we define the zeta functions related to the contributions of the identity, hyperbolic, elliptic and parabolic conjugacy classes in Selberg's trace formula. We present Selberg's zeta function in terms of a regu......For a general Fuchsian group of the first kind with an arbitrary unitary representation we define the zeta functions related to the contributions of the identity, hyperbolic, elliptic and parabolic conjugacy classes in Selberg's trace formula. We present Selberg's zeta function in terms...... of a regularized determinant of the automorphic Laplacian. We also present the zeta function for the identity contribution in terms of a regularized determinant of the Laplacian on the two dimensional sphere. We express the zeta functions for the elliptic and parabolic contributions in terms of certain regularized...... determinants of one dimensional Schroedinger operator for harmonic oscillator. We decompose the determinant of the automorphic Laplacian into a product of the determinants where each factor is a determinant representation of a zeta function related to Selberg's trace formula. Then we derive an identity...

  2. Efeito Protetor da Corrida Voluntária Regular na Toxicidade Hepática Induzida pela Administração Prolongada de Doxorrubicina em Ratos Wistar

    OpenAIRE

    Márcio Fernando Martins Cruz

    2017-01-01

    O cancro tornou-se nas últimas décadas uma doença progressivamente mais prevalente, adquirindo hoje, nos países ocidentais, um carater epidémico. A doxorrubicina (DOX), uma antraciclina usada no tratamento de diversos cancros, encontra-se associada ao aparecimento de vários efeitos colaterais indesejáveis, resultantes da sua toxicidade nos mais diversos órgãos e tecidos em doentes oncológicos. O metabolismo de alguns fármacos, em particular da DOX, pode a curto e a longo prazo tornar-se preju...

  3. Benefits of regular aerobic exercise for executive functioning in healthy populations.

    Science.gov (United States)

    Guiney, Hayley; Machado, Liana

    2013-02-01

    Research suggests that regular aerobic exercise has the potential to improve executive functioning, even in healthy populations. The purpose of this review is to elucidate which components of executive functioning benefit from such exercise in healthy populations. In light of the developmental time course of executive functions, we consider separately children, young adults, and older adults. Data to date from studies of aging provide strong evidence of exercise-linked benefits related to task switching, selective attention, inhibition of prepotent responses, and working memory capacity; furthermore, cross-sectional fitness data suggest that working memory updating could potentially benefit as well. In young adults, working memory updating is the main executive function shown to benefit from regular exercise, but cross-sectional data further suggest that task-switching and post error performance may also benefit. In children, working memory capacity has been shown to benefit, and cross-sectional data suggest potential benefits for selective attention and inhibitory control. Although more research investigating exercise-related benefits for specific components of executive functioning is clearly needed in young adults and children, when considered across the age groups, ample evidence indicates that regular engagement in aerobic exercise can provide a simple means for healthy people to optimize a range of executive functions.

  4. On the regularization of extremal three-point functions involving giant gravitons

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    Charlotte Kristjansen

    2015-11-01

    Full Text Available In the AdS5/CFT4 set-up, extremal three-point functions involving two giant 1/2 BPS gravitons and one point-like 1/2 BPS graviton, when calculated using semi-classical string theory methods, match the corresponding three-point functions obtained in the tree-level gauge theory. The string theory computation relies on a certain regularization procedure whose justification is based on the match between gauge and string theory. We revisit the regularization procedure and reformulate it in a way which allows a generalization to the ABJM set-up where three-point functions of 1/2 BPS operators are not protected and where a match between tree-level gauge theory and semi-classical string theory is hence not expected.

  5. Structural damage detection by a new iterative regularization method and an improved sensitivity function

    Science.gov (United States)

    Entezami, Alireza; Shariatmadar, Hashem; Sarmadi, Hassan

    2017-07-01

    A new sensitivity-based damage detection method is proposed to identify and estimate the location and severity of structural damage using incomplete noisy modal data. For these purposes, an improved sensitivity function of modal strain energy (MSE) based on Lagrange optimization problem is derived to adapt the initial sensitivity formulation of MSE to damage detection problem with the aid of new mathematical approaches. In the presence of incomplete noisy modal data, the sensitivity matrix is sparse, rectangular, and ill-conditioned, which leads to an ill-posed damage equation. To overcome this issue, a new regularization method named as Regularized Least Squares Minimal Residual (RLSMR) is proposed to solve the ill-posed damage equation. This method relies on Krylov subspace and exploits bidiagonalization and iterative algorithms to solve linear mathematical systems. For the majority of Krylov subspace methods, conventional direct methods for the determination of an optimal regularization parameter may not be proper. To cope with this limitation, a hybrid technique is introduced that depends on the residual of RLSMR method, the number of iterations, and the bidiagonalization algorithm. The accuracy and performance of the improved and proposed methods are numerically examined by a planner truss by incorporating incomplete noisy modal parameters and finite element modeling errors. A comparative study on the initial and improved sensitivity functions is conduced to investigate damage detectability of these sensitivity formulations. Furthermore, the accuracy and robustness of RLSMR method in detecting damage are compared with the well-known Tikhonov regularization method. Results show that the improved sensitivity of MSE is an efficient tool for using in the damage detection problem due to a high sensitivity to damage and reliable damage detectability in comparison with the initial sensitivity function. Additionally, it is observed that the RLSMR method with the aid

  6. [Regularities of structural and functional visual system changes in patients with myopic refraction and presbyopia].

    Science.gov (United States)

    Rozanova, O I; Seliverstova, N N; Shchuko, A G; Malyshev, V V

    2013-01-01

    Two age groups of 57 patients with noncomplicated low or moderate myopia were examined to reveal the regularities of structural and functional visual system changes in patients with myopic refraction and presbyopia. Characteristics of visual impression, anatomic and physiologic parameters were studied. Presbyopia development in patients with myopic refraction was found to occur on the background of significant changes in anatomic proportions and optic parameters of the eye, decrease of functional capability of visual system and development of abnormal functional system of visual perception. The key mechanisms of presbyopia development in myopia besides the accommodation decrease are pupil dysfunction and binocular interactions disintegration i. e. all the near vision reflex components.

  7. Efeitos de um programa regular de atividade generalizada sobre os distúrbios motores de uma pessoa com doença de Parkinson The Effects of a Regular Physical Activity Program on the Motor Disorders of a Parkinson Patient. Efectos de un programa regular de actividad generalizada sobre los disturbios motores de una persona con enfermedad de parkinson

    Directory of Open Access Journals (Sweden)

    2006-11-01

    Full Text Available O objetivo deste estudo foi analisar os efeitos de seis meses de um programa regular de atividade física sobre os distúrbios motores em uma pessoa idosa com a doença de parkinson. O sujeito pesquisado foi uma pessoa idosa do sexo feminino, sedentária, portadora da doença há dez anos. O programa foi desenvolvido durante seis meses com o apoio do Centro Goiano de Neurologia e Neurocirurgia. Para avaliar o nível de rigidez, a bradicinesia, a capacidade de se levantar da cadeira e se locomover e as alterações posturais foi utilizado um exame motor (BRITO, 1998, com avaliações antes e após o programa. Com dois meses de atividade física houve melhora na rigidez, na bradicinesia e no equilíbrio, contribuindo para a autonomia e independência do sujeito pesquisado. PALAVRAS-CHAVE: Doença de Parkinson – Idoso – Atividade física This study aims at analyzing the effects of a six-month program of regular physical activity upon the motor disorders of an elderly Parkinson patient. The subject was an elderly, physically inactive woman, who has had Parkinson for ten years. The six-month program was developed with the help of the Centro Goiano de Neurologia e Neurocirurgia (The Goianian Center for Neurology and Neuro-surgery. A motor exam (Brito, 1998 was used to evaluate the level of rigidness, bradicinesia, the capacity to raise from a chair and walk, and posture changes. Evaluations were conducted before and after the program. After two months of regular physical activity, improvements were noticed on rigidness, bradicinesia, and balance, which brought autonomy and independence to the subject. KEY-WORDS: Parkinson - elderly - physical activity El objetivo de este estudio fue analizar los efectos de seis meses de un programa regular de actividad física sobre los disturbios motores en una persona mayor con la enfermedad de parkinson. El sujeto investigado fue una persona mayor del sexo femenino, sedentaria portadora de la enfermedad

  8. Maximal ? -regularity

    NARCIS (Netherlands)

    Van Neerven, J.M.A.M.; Veraar, M.C.; Weis, L.

    2015-01-01

    In this paper, we prove maximal regularity estimates in “square function spaces” which are commonly used in harmonic analysis, spectral theory, and stochastic analysis. In particular, they lead to a new class of maximal regularity results for both deterministic and stochastic equations in L p

  9. Regular Functions with Values in Ternary Number System on the Complex Clifford Analysis

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    Ji Eun Kim

    2013-01-01

    Full Text Available We define a new modified basis i^ which is an association of two bases, e1 and e2. We give an expression of the form z=x0+ i ^z0-, where x0 is a real number and z0- is a complex number on three-dimensional real skew field. And we research the properties of regular functions with values in ternary field and reduced quaternions by Clifford analysis.

  10. Determination of Lateral Modulation Apodization Functions Using a Regularized, Weighted Least Squares Estimation

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    Chikayoshi Sumi

    2010-01-01

    Full Text Available Recently, work in this group has focused on the lateral cosine modulation method (LCM which can be used for next-generation ultrasound (US echo imaging and tissue displacement vector/strain tensor measurements (blood, soft tissues, etc.. For instance, in US echo imaging, a high lateral spatial resolution as well as a high axial spatial resolution can be obtained, and in tissue displacement vector measurements, accurate measurements of lateral tissue displacements as well as of axial tissue displacements can be realized. For an optimal determination of an apodization function for the LCM method, the regularized, weighted minimum-norm least squares (WMNLSs estimation method is presented in this study. For designed Gaussian-type point spread functions (PSFs with lateral modulation as an example, the regularized WMNLS estimation in simulations yields better approximations of the designed PSFs having wider lateral bandwidths than a Fraunhofer approximation and a singular-value decomposition (SVD. The usefulness of the regularized WMNLS estimation for the determination of apodization functions is demonstrated.

  11. On the regularization of regional gravity field solutions in spherical radial base functions

    Science.gov (United States)

    Naeimi, Majid; Flury, Jakob; Brieden, Phillip

    2015-08-01

    Regional refinement of the gravity field models from satellite data using spherical radial base functions (SRBF) is an ill-posed problem. This is mainly due to the regional confinement of the data and the base functions, which leads to severe instabilities in the solutions. Here, this ill-posedness as well as the related regularization process are investigated. We compare three methods for the choice of the regularization parameter, which have been frequently used in gravity modelling. These methods are (1) the variance component estimation (VCE), (2) the generalized cross validation (GCV) and (3) the L-curve criterion. A particular emphasis is put on the impact of the SRBF type on the regularization parameter. To do this, we include two types of SRBF which are often used for regional gravity field modelling. These are the Shannon SRBF or the reproducing kernel and the Spline SRBF. The investigations are performed on two months of the real GOCE ultrasensitive gravity gradients over Central Africa and Amazon. The solutions are validated against a state-of-the-art global gravity solution. We conclude that if a proper regularization method is applied, both SRBF deliver more or less the same accuracy. We show that when the Shannon wavelet is used, the L-curve method gives the best results, while with the Spline kernel, the GCV outperforms the other two methods. Moreover, we observe that the estimated coefficients for the Spline kernel cannot be spatially interpreted. In contrast, the coefficients obtained for the Shannon wavelet reflect the energy of the recovered gravity field with a correlation factor of above 95 per cent. Therefore, when combined with the L-curve method, the Shannon SRBF is advantageous for regional gravity field estimation, since it is one of the simplest band-limited SRBF. In addition, it delivers promising solutions and the estimated coefficients represent the characteristics of the gravity field within the target region.

  12. The three-point function in split dimensional regularization in the Coulomb gauge

    CERN Document Server

    Leibbrandt, G

    1998-01-01

    We use a gauge-invariant regularization procedure, called ``split dimensional regularization'', to evaluate the quark self-energy $\\Sigma (p)$ and quark-quark-gluon vertex function $\\Lambda_\\mu (p^\\prime,p)$ in the Coulomb gauge, $\\vec{\\bigtriangledown}\\cdot\\vec{A}^a = 0$. The technique of split dimensional regularization was designed to regulate Coulomb-gauge Feynman integrals in non-Abelian theories. The technique which is based on two complex regulating parameters, $\\omega$ and $\\sigma$, is shown to generate a well-defined set of Coulomb-gauge integrals. A major component of this project deals with the evaluation of four-propagator and five-propagator Coulomb integrals, some of which are nonlocal. It is further argued that the standard one-loop BRST identity relating $\\Sigma$ and $\\Lambda_\\mu$, should by rights be replaced by a more general BRST identity which contains two additional contributions from ghost vertex diagrams. Despite the appearance of nonlocal Coulomb integrals, both $\\Sigma$ and $\\Lambda_\\...

  13. Three-dimensional ionospheric tomography reconstruction using the model function approach in Tikhonov regularization

    Science.gov (United States)

    Wang, Sicheng; Huang, Sixun; Xiang, Jie; Fang, Hanxian; Feng, Jian; Wang, Yu

    2016-12-01

    Ionospheric tomography is based on the observed slant total electron content (sTEC) along different satellite-receiver rays to reconstruct the three-dimensional electron density distributions. Due to incomplete measurements provided by the satellite-receiver geometry, it is a typical ill-posed problem, and how to overcome the ill-posedness is still a crucial content of research. In this paper, Tikhonov regularization method is used and the model function approach is applied to determine the optimal regularization parameter. This algorithm not only balances the weights between sTEC observations and background electron density field but also converges globally and rapidly. The background error covariance is given by multiplying background model variance and location-dependent spatial correlation, and the correlation model is developed by using sample statistics from an ensemble of the International Reference Ionosphere 2012 (IRI2012) model outputs. The Global Navigation Satellite System (GNSS) observations in China are used to present the reconstruction results, and measurements from two ionosondes are used to make independent validations. Both the test cases using artificial sTEC observations and actual GNSS sTEC measurements show that the regularization method can effectively improve the background model outputs.

  14. Physical Quantities of Reissner-Nordström Spacetime with Arbitrary Function and Regularized Procedure

    Directory of Open Access Journals (Sweden)

    Gamal G. L. Nashed

    2013-01-01

    Full Text Available We use the covariant teleparallel approach to compute the total energy of a spherically symmetric frame with an arbitrary function, that is, ℑ(r. We show how the total energy is always effected by the inertia. When use is made of the pure gauge connection, teleparallel gravity always yields the physically relevant result. We also calculate the total conserved charge and show how inertia spoils the physics in the time coordinate direction. Therefore, a regularized expression is employed to get a plausible value of energy. Finally, we use the Euclidean continuation method, in the context of TEGR, to calculate the energy, Hawking temperature, entropy, and first law of thermodynamics.

  15. A regularized clustering approach to brain parcellation from functional MRI data

    Science.gov (United States)

    Dillon, Keith; Wang, Yu-Ping

    2017-08-01

    We consider a data-driven approach for the subdivision of an individual subject's functional Magnetic Resonance Imaging (fMRI) scan into regions of interest, i.e., brain parcellation. The approach is based on a computational technique for calculating resolution from inverse problem theory, which we apply to neighborhood selection for brain connectivity networks. This can be efficiently calculated even for very large images, and explicitly incorporates regularization in the form of spatial smoothing and a noise cutoff. We demonstrate the reproducibility of the method on multiple scans of the same subjects, as well as the variations between subjects.

  16. The Analysis of Two-Way Functional Data Using Two-Way Regularized Singular Value Decompositions

    KAUST Repository

    Huang, Jianhua Z.

    2009-12-01

    Two-way functional data consist of a data matrix whose row and column domains are both structured, for example, temporally or spatially, as when the data are time series collected at different locations in space. We extend one-way functional principal component analysis (PCA) to two-way functional data by introducing regularization of both left and right singular vectors in the singular value decomposition (SVD) of the data matrix. We focus on a penalization approach and solve the nontrivial problem of constructing proper two-way penalties from oneway regression penalties. We introduce conditional cross-validated smoothing parameter selection whereby left-singular vectors are cross- validated conditional on right-singular vectors, and vice versa. The concept can be realized as part of an alternating optimization algorithm. In addition to the penalization approach, we briefly consider two-way regularization with basis expansion. The proposed methods are illustrated with one simulated and two real data examples. Supplemental materials available online show that several "natural" approaches to penalized SVDs are flawed and explain why so. © 2009 American Statistical Association.

  17. Long-term, regular remote ischemic preconditioning improves endothelial function in patients with coronary heart disease

    Directory of Open Access Journals (Sweden)

    Y. Liang

    2015-06-01

    Full Text Available Remote ischemic preconditioning (RIPre can prevent myocardial injury. The purpose of this study was to assess the beneficial effects of long-term regular RIPre on human arteries. Forty patients scheduled for coronary artery bypass graft (CABG surgery were assigned randomly to a RIPre group (n=20 or coronary heart disease (CHD group (n=20. Twenty patients scheduled for mastectomy were enrolled as a control group. RIPre was achieved by occluding arterial blood flow 5 min with a mercury sphygmomanometer followed by a 5-min reperfusion period, and this was repeated 4 times. The RIPre procedure was repeated 3 times a day for 20 days. In all patients, arterial fragments discarded during surgery were collected to evaluate endothelial function by flow-mediated dilation (FMD, CD34+ monocyte count, and endothelial nitric oxide synthase (eNOS expression. Phosphorylation levels of STAT-3 and Akt were also assayed to explore the underlying mechanisms. Compared with the CHD group, long-term regular RIPre significantly improved FMD after 20 days (8.5±2.4 vs 4.9±4.2%, P<0.05 and significantly reduced troponin after CABG surgery (0.72±0.31 and 1.64±0.19, P<0.05. RIPre activated STAT-3 and increased CD34+ endothelial progenitor cell counts found in arteries. Long-term, regular RIPre improved endothelial function in patients with CHD, possibly due to STAT-3 activation, and this may have led to an increase in endothelial progenitor cells.

  18. Long-term, regular remote ischemic preconditioning improves endothelial function in patients with coronary heart disease

    Energy Technology Data Exchange (ETDEWEB)

    Liang, Y.; Li, Y.P.; He, F.; Liu, X.Q.; Zhang, J.Y. [Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou (China)

    2015-04-28

    Remote ischemic preconditioning (RIPre) can prevent myocardial injury. The purpose of this study was to assess the beneficial effects of long-term regular RIPre on human arteries. Forty patients scheduled for coronary artery bypass graft (CABG) surgery were assigned randomly to a RIPre group (n=20) or coronary heart disease (CHD) group (n=20). Twenty patients scheduled for mastectomy were enrolled as a control group. RIPre was achieved by occluding arterial blood flow 5 min with a mercury sphygmomanometer followed by a 5-min reperfusion period, and this was repeated 4 times. The RIPre procedure was repeated 3 times a day for 20 days. In all patients, arterial fragments discarded during surgery were collected to evaluate endothelial function by flow-mediated dilation (FMD), CD34{sup +} monocyte count, and endothelial nitric oxide synthase (eNOS expression). Phosphorylation levels of STAT-3 and Akt were also assayed to explore the underlying mechanisms. Compared with the CHD group, long-term regular RIPre significantly improved FMD after 20 days (8.5±2.4 vs 4.9±4.2%, P<0.05) and significantly reduced troponin after CABG surgery (0.72±0.31 and 1.64±0.19, P<0.05). RIPre activated STAT-3 and increased CD34{sup +} endothelial progenitor cell counts found in arteries. Long-term, regular RIPre improved endothelial function in patients with CHD, possibly due to STAT-3 activation, and this may have led to an increase in endothelial progenitor cells.

  19. Determining functional units of tongue motion via graph-regularized sparse non-negative matrix factorization.

    Science.gov (United States)

    Woo, Jonghye; Xing, Fangxu; Lee, Junghoon; Stone, Maureen; Prince, Jerry L

    2014-01-01

    Tongue motion during speech and swallowing involves synergies of locally deforming regions, or functional units. Motion clustering during tongue motion can be used to reveal the tongue's intrinsic functional organization. A novel matrix factorization and clustering method for tissues tracked using tagged magnetic resonance imaging (tMRI) is presented. Functional units are estimated using a graph-regularized sparse non-negative matrix factorization framework, learning latent building blocks and the corresponding weighting map from motion features derived from tissue displacements. Spectral clustering using the weighting map is then performed to determine the coherent regions--i.e., functional units--efined by the tongue motion. Two-dimensional image data is used to ver-fy that the proposed algorithm clusters the different types of images ac-urately. Three-dimensional tMRI data from five subjects carrying out simple non-speech/speech tasks are analyzed to show how the proposed approach defines a subject/task-specific functional parcellation of the tongue in localized regions.

  20. The clinical value of regular thyroid function tests during amiodarone treatment.

    Science.gov (United States)

    Benjamens, Stan; Dullaart, Robin P F; Sluiter, Wim J; Rienstra, Michiel; van Gelder, Isabelle C; Links, Thera P

    2017-07-01

    Amiodarone is used for the maintenance of sinus rhythm in patients with arrhythmias, but thyroid dysfunction (amiodarone-induced thyrotoxicosis (AIT) or amiodarone-induced hypothyroidism (AIH)) is a common adverse effect. As the onset of AIT and AIH may be unpredictable, the value of long-term regular monitoring of amiodarone treated patients for thyroid dysfunction is still uncertain. We retrospectively documented the frequency at which overt thyroid dysfunction was preceded by subclinical thyroid dysfunction. We included 303 patients treated with amiodarone between 1984 and 2007. AIT was defined as a lowered TSH level with an elevated free thyroxine (FT4) and AIH was defined as an elevated TSH level with a decreased or subnormal FT4. Subclinical AIT was defined as a lowered TSH level with a normal FT4 and subclinical AIH as an elevated TSH level with a normal FT4. 200 men and 103 women, aged 62 ± 12.0 years, suffering from atrial (260) or ventricular (43) arrhythmias, were evaluated. During a median follow-up of 2.8 (1.0-25) years, 44 patients developed AIT and 33 AIH. In 42 (55%) patients who developed AIT/AIH, earlier thyroid function tests showed no subclinical AIT or subclinical AIH. In 35 (45%) patients, AIT/AIH was preceded by subclinical AIT or subclinical AIH (16/44 for AIT and 19/33 for AIH). In a considerable proportion of patients who developed AIT/AIH, earlier thyroid function tests showed no subclinical AIT/AIH. Less than half of the patients with a subclinical event subsequently developed overt AIT/AIH. This study provides data to reconsider the yield of regular testing of thyroid function to predict overt thyroid dysfunction in amiodarone treated patients. © 2017 European Society of Endocrinology.

  1. Rank-shaping regularization of exponential spectral analysis for application to functional parametric mapping

    Energy Technology Data Exchange (ETDEWEB)

    Turkheimer, Federico E [Hammersmith Imanet, Cyclotron Building, Hammersmith Hospital, Du Cane Road, London W12 0NN (United Kingdom); Hinz, Rainer [Hammersmith Imanet, Cyclotron Building, Hammersmith Hospital, Du Cane Road, London W12 0NN (United Kingdom); Gunn, Roger N [McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, 3801 University St., Montreal H3A 2B4 (Canada); Aston, John A D [Statistical Research Division, US Bureau of the Census, 4700 Silver Hill Road, Washington DC 20233 (United States); Gunn, Steve R [Image, Speech and Intelligent Systems Research Group, University of Southampton, Highfield, Southampton SO17 1BJ (United Kingdom); Cunningham, Vincent J [Hammersmith Imanet, Cyclotron Building, Hammersmith Hospital, Du Cane Road, London W12 0NN (United Kingdom)

    2003-12-07

    Compartmental models are widely used for the mathematical modelling of dynamic studies acquired with positron emission tomography (PET). The numerical problem involves the estimation of a sum of decaying real exponentials convolved with an input function. In exponential spectral analysis (SA), the nonlinear estimation of the exponential functions is replaced by the linear estimation of the coefficients of a predefined set of exponential basis functions. This set-up guarantees fast estimation and attainment of the global optimum. SA, however, is hampered by high sensitivity to noise and, because of the positivity constraints implemented in the algorithm, cannot be extended to reference region modelling. In this paper, SA limitations are addressed by a new rank-shaping (RS) estimator that defines an appropriate regularization over an unconstrained least-squares solution obtained through singular value decomposition of the exponential base. Shrinkage parameters are conditioned on the expected signal-to-noise ratio. Through application to simulated and real datasets, it is shown that RS ameliorates and extends SA properties in the case of the production of functional parametric maps from PET studies.

  2. Cardiac Adaptations (Structural and Functional to Regular Mountain Activities in Middle-aged Men

    Directory of Open Access Journals (Sweden)

    Abbas Saremi

    2017-09-01

    Full Text Available Abstract Background: Physical exercise is an important and effective part of comprehensive care of seniors, which declines aging progression. Because of the importance of physical activity in cardiovascular diseases prevention this study intends to investigate the comparision of structural and functional characterictics of the heart between middle- aged montaineer men and non-athlete peers. Materials and Methods: In this cross-sectional and descriptive–analytical study, 13 middle- aged montaineer (age: 54.5±2.0 y, body mass index: 25.59±2.4 kg/m2 who have continues mountain activities during previous 24 months for at least 2 sessions per week, each session lasted 120 minute, and 14 sedentary, healthy peers (age: 54.1±2.2 y, body mass index: 26.8±2.3 kg/m2 who were not currently experiencing any regular physical activity (at least 6 months, were selected. All subjects underwent standard two-dimensional and Doppler echocardiography at rest. Cardio respiratory fitness was assessed using Bruce test. T test was used to compare groups with α=0.05. Results: The results showed that mountain activities significantly increased left ventricular mass (p=0.03 and left-ventricular-end-diastolic-diameter (p=0.04. We also observed that systolic blood pressure (p=0.04, ejection fraction (p=0.05, stroke volume (p=0.03 and cardio respiratory fitness (p=0.03 were significantly improved by mountain climbing. In some of parameters such as shortening fraction, interventicular septum and left ventricular posterior wall there were no significant differences between groups (p>0.05. Conclusion: These results suggest that regular mountain sports activities can have beneficial effects on structural and functional characterictics of the heart in middle-aged men.

  3. Moderate, Regular Alcohol Consumption is Associated with Higher Cognitive Function in Older Community-Dwelling Adults.

    Science.gov (United States)

    Reas, E T; Laughlin, G A; Kritz-Silverstein, D; Barrett-Connor, E; McEvoy, L K

    2016-09-01

    Evidence suggests that moderate alcohol consumption may protect against cognitive decline and dementia. However, uncertainty remains over the patterns of drinking that are most beneficial. To examine associations between amount and frequency of alcohol consumption with multiple domains of cognitive function in a well-characterized cohort of older community-dwelling adults in southern California. Observational, cross-sectional cohort study. A research visit between 1988-1992 in Rancho Bernardo, California. 1624 participants of the Rancho Bernardo Study (mean age ± SD = 73.2 ± 9.3 years). Measurements: Participants completed a neuropsychological test battery, self-administered questionnaires on alcohol consumption and lifestyle, and a clinical health evaluation. We classified participants according to average amount of alcohol intake into never, former, moderate, heavy and excessive drinkers, and according to frequency of alcohol intake, into non-drinkers, rare, infrequent, frequent and daily drinkers. We examined the association between alcohol intake and cognitive function, controlling for age, sex, education, exercise, smoking, waist-hip ratio, hypertension and self-assessed health. Amount and frequency of alcohol intake were significantly associated with cognitive function, even after controlling for potentially related health and lifestyle variables. Global and executive function showed positive linear associations with amount and frequency of alcohol intake, whereas visual memory showed an inverted U-shaped association with alcohol intake, with better performance for moderate and infrequent drinkers than for non-drinkers, excessive drinkers or daily drinkers. In several cognitive domains, moderate, regular alcohol intake was associated with better cognitive function relative to not drinking or drinking less frequently. This suggests that beneficial cognitive effects of alcohol intake may be achieved with low levels of drinking that are unlikely to be

  4. Ventricular action potential adaptation to regular exercise: role of β-adrenergic and KATPchannel function.

    Science.gov (United States)

    Wang, Xinrui; Fitts, Robert H

    2017-08-01

    Regular exercise training is known to affect the action potential duration (APD) and improve heart function, but involvement of β-adrenergic receptor (β-AR) subtypes and/or the ATP-sensitive K + (K ATP ) channel is unknown. To address this, female and male Sprague-Dawley rats were randomly assigned to voluntary wheel-running or control groups; they were anesthetized after 6-8 wk of training, and myocytes were isolated. Exercise training significantly increased APD of apex and base myocytes at 1 Hz and decreased APD at 10 Hz. Ca 2+ transient durations reflected the changes in APD, while Ca 2+ transient amplitudes were unaffected by wheel running. The nonselective β-AR agonist isoproterenol shortened the myocyte APD, an effect reduced by wheel running. The isoproterenol-induced shortening of APD was largely reversed by the selective β 1 -AR blocker atenolol, but not the β 2 -AR blocker ICI 118,551, providing evidence that wheel running reduced the sensitivity of the β 1 -AR. At 10 Hz, the K ATP channel inhibitor glibenclamide prolonged the myocyte APD more in exercise-trained than control rats, implicating a role for this channel in the exercise-induced APD shortening at 10 Hz. A novel finding of this work was the dual importance of altered β 1 -AR responsiveness and K ATP channel function in the training-induced regulation of APD. Of physiological importance to the beating heart, the reduced response to adrenergic agonists would enhance cardiac contractility at resting rates, where sympathetic drive is low, by prolonging APD and Ca 2+ influx; during exercise, an increase in K ATP channel activity would shorten APD and, thus, protect the heart against Ca 2+ overload or inadequate filling. NEW & NOTEWORTHY Our data demonstrated that regular exercise prolonged the action potential and Ca 2+ transient durations in myocytes isolated from apex and base regions at 1-Hz and shortened both at 10-Hz stimulation. Novel findings were that wheel running shifted the

  5. A Disorder of Menstrual Function Regularization and its Influence on a Female Reproductive Potential

    Directory of Open Access Journals (Sweden)

    Oksana Makarchuk

    2017-10-01

    Full Text Available Obstetric complications in women of reproductive age are often the result of puberty disorders which remain underestimated and not taken into account in pregnancy monitoring programs in such patients, leading to an increase of habitual non-carrying of pregnancy and negative obstetric effects. The objective of the research is to carry out a comprehensive multivariate assessment of the disturbances of the body adaptive processes in teenage girls, taking into account the data of anamnesis regarding the specifics of menstrual function regularization during puberty, and to determine the main factors of complicated pregnancy in this category of patients. Materials and methods. To carry out the task, 110 pregnant women with a disorder of menstrual function regularizationhave been prospectively examined (the main group; the examination was performed at the preconception stage and in the periods of 6-12, 22-24 and 32-36 weeks of pregnancy. The comparison group consisted of 30 patients with a normal menstrual cycle. In order to identify risk factors and predict complications, the odds ratio (OR and its 95% confidence interval were used. Results. Extragenital pathology plays a significant role in the formation of pathological course of puberty and obstetric complications; 87.27% ofsuch cases were demonstrated in our study. Among the disorders of the ovarian-menstrual cycle, the structural significance is characteristic to the failure of the luteal phase and anovulatory disorders (78.18% of cases. Gynaecologic pathology includes inflammatory diseases of the pelvic organs (35.45%, cervical background processes (41.66%, ovarian tumour lesions (21.81, and primary infertility(14.54%. The obtained results of the structure of pregnancy complications in patients of the main group show reproductive losses in early pregnancy (11.8%, subchorionic hematoma (28.18% and the threat of late spontaneous abortion; these data are notedthree times more often than in the

  6. Função lútea em adolescentes normais com ciclos menstruais regulares Luteal function in normal adolescents with regular menstrual cycles

    Directory of Open Access Journals (Sweden)

    Zuleide Aparecida Felix Cabral

    2005-09-01

    Full Text Available OBJETIVO: examinar a função lútea em adolescentes com ciclos menstruais regulares. MÉTODOS: foram incluídas neste estudo, de coorte prospectivo, 55 adolescentes eumenorrêicas, com idade entre 14 e 19 anos e menarca aos 12,2 anos. Examinaram-se o dia da ocorrência de ovulação, o grau de vascularização do corpo lúteo e o índice de resistência dos vasos ovarianos, as concentrações de progesterona e a resposta do endométrio. A ovulação foi identificada por ultra-sonografia transvaginal a partir do 2º ou 5º dia do ciclo, repetindo-a a cada dois dias. A vascularização e o índice de resistência lútea foram aferidos por dopplervelocimetria no 10º dia pós-ovulação. Os níveis de progesterona sérica foram estimados por quimioluminescência nos dias 6, 9 e 12 da fase lútea. A histologia endometrial foi analisada após biópsia feita entre o 8º e o 10º dia pós-ovulação. Usou-se software SPSS para análise estatística, assumindo-se significância quando pPURPOSE: to evaluate the luteal function in adolescents with regular menstrual cycles. METHODS: this prospective cohort study included 55 adolescents, aged 14-19 years, with menarche at 12.2 years. Ovulation was identified by ultrasound, starting on the second or fifth day of the cycle. The corpus luteum vascularization and the resistence index of the ovarian vessels were measured by Doppler on the tenth postovulatory day. Progesterone was measured by chemoluminescence on days 6, 9 and 12 of the luteal phase. The endometrial biopsy was performed 8 to 10 days after ovulation. The results were analyzed using the SPSS software and were considered significant when p<0.05. RESULTS: on average ovulation was on day 17. Progesterone levels were 11.4, 10.9 and 3.9 ng/mL on days 6, 9, and 12 after ovulation, respectively; the progesterone mean during the whole luteal phase was 10.3 ng/ml. Luteal vascularization was scarce in 34.6%, mild in 23.6% and exuberant in 41.8%. The

  7. Sinc-interpolants in the energy plane for regular solution, Jost function, and its zeros of quantum scattering

    Science.gov (United States)

    Annaby, M. H.; Asharabi, R. M.

    2018-01-01

    In a remarkable note of Chadan [Il Nuovo Cimento 39, 697-703 (1965)], the author expanded both the regular wave function and the Jost function of the quantum scattering problem using an interpolation theorem of Valiron [Bull. Sci. Math. 49, 181-192 (1925)]. These expansions have a very slow rate of convergence, and applying them to compute the zeros of the Jost function, which lead to the important bound states, gives poor convergence rates. It is our objective in this paper to introduce several efficient interpolation techniques to compute the regular wave solution as well as the Jost function and its zeros approximately. This work continues and improves the results of Chadan and other related studies remarkably. Several worked examples are given with illustrations and comparisons with existing methods.

  8. Age of acquisition modulates neural activity for both regular and irregular syntactic functions.

    Science.gov (United States)

    Hernandez, Arturo E; Hofmann, Juliane; Kotz, Sonja A

    2007-07-01

    Studies have found that neural activity is greater for irregular grammatical items than regular items. Findings with monolingual Spanish speakers have revealed a similar effect when making gender decisions for visually presented nouns. The current study extended previous studies by looking at the role of regularity in modulating differences in groups that differ in the age of acquisition of a language. Early and late learners of Spanish matched on measures of language proficiency were asked to make gender decisions to regular (-o for masculine and -a for feminine) and irregular items (which can end in e, l, n, r, s, t and z). Results revealed increased activity in left BA 44 for irregular compared to regular items in separate comparisons for both early and late learners. In addition, within-group comparisons revealed that neural activity for irregulars extended into left BA 47 for late learners and into left BA 6 for early learners. Direct comparisons between groups revealed increased activity in left BA 44/45 for irregular items indicating the need for more extensive syntactic processing in late learners. The results revealed that processing of irregular grammatical gender leads to increased activity in left BA 44 and adjacent areas in the left IFG regardless of when a language is learned. Furthermore, these findings suggest differential recruitment of brain areas associated with grammatical processing in late learners. The results are discussed with regard to a model which considers L2 learning as emerging from the competitive interplay between two languages.

  9. Research on image retrieval using deep convolutional neural network combining L1 regularization and PRelu activation function

    Science.gov (United States)

    QingJie, Wei; WenBin, Wang

    2017-06-01

    In this paper, the image retrieval using deep convolutional neural network combined with regularization and PRelu activation function is studied, and improves image retrieval accuracy. Deep convolutional neural network can not only simulate the process of human brain to receive and transmit information, but also contains a convolution operation, which is very suitable for processing images. Using deep convolutional neural network is better than direct extraction of image visual features for image retrieval. However, the structure of deep convolutional neural network is complex, and it is easy to over-fitting and reduces the accuracy of image retrieval. In this paper, we combine L1 regularization and PRelu activation function to construct a deep convolutional neural network to prevent over-fitting of the network and improve the accuracy of image retrieval

  10. Assessing cardiac function from total-variation-regularized 4D C-arm CT in the presence of angular undersampling

    Science.gov (United States)

    Taubmann, O.; Haase, V.; Lauritsch, G.; Zheng, Y.; Krings, G.; Hornegger, J.; Maier, A.

    2017-04-01

    Time-resolved tomographic cardiac imaging using an angiographic C-arm device may support clinicians during minimally invasive therapy by enabling a thorough analysis of the heart function directly in the catheter laboratory. However, clinically feasible acquisition protocols entail a highly challenging reconstruction problem which suffers from sparse angular sampling of the trajectory. Compressed sensing theory promises that useful images can be recovered despite massive undersampling by means of sparsity-based regularization. For a multitude of reasons—most notably the desired reduction of scan time, dose and contrast agent required—it is of great interest to know just how little data is actually sufficient for a certain task. In this work, we apply a convex optimization approach based on primal-dual splitting to 4D cardiac C-arm computed tomography. We examine how the quality of spatially and temporally total-variation-regularized reconstruction degrades when using as few as 6.9+/- 1.2 projection views per heart phase. First, feasible regularization weights are determined in a numerical phantom study, demonstrating the individual benefits of both regularizers. Secondly, a task-based evaluation is performed in eight clinical patients. Semi-automatic segmentation-based volume measurements of the left ventricular blood pool performed on strongly undersampled images show a correlation of close to 99% with measurements obtained from less sparsely sampled data.

  11. Robust Detection of Impaired Resting State Functional Connectivity Networks in Alzheimer's Disease Using Elastic Net Regularized Regression

    Science.gov (United States)

    Teipel, Stefan J.; Grothe, Michel J.; Metzger, Coraline D.; Grimmer, Timo; Sorg, Christian; Ewers, Michael; Franzmeier, Nicolai; Meisenzahl, Eva; Klöppel, Stefan; Borchardt, Viola; Walter, Martin; Dyrba, Martin

    2017-01-01

    The large number of multicollinear regional features that are provided by resting state (rs) fMRI data requires robust feature selection to uncover consistent networks of functional disconnection in Alzheimer's disease (AD). Here, we compared elastic net regularized and classical stepwise logistic regression in respect to consistency of feature selection and diagnostic accuracy using rs-fMRI data from four centers of the “German resting-state initiative for diagnostic biomarkers” (psymri.org), comprising 53 AD patients and 118 age and sex matched healthy controls. Using all possible pairs of correlations between the time series of rs-fMRI signal from 84 functionally defined brain regions as the initial set of predictor variables, we calculated accuracy of group discrimination and consistency of feature selection with bootstrap cross-validation. Mean areas under the receiver operating characteristic curves as measure of diagnostic accuracy were 0.70 in unregularized and 0.80 in regularized regression. Elastic net regression was insensitive to scanner effects and recovered a consistent network of functional connectivity decline in AD that encompassed parts of the dorsal default mode as well as brain regions involved in attention, executive control, and language processing. Stepwise logistic regression found no consistent network of AD related functional connectivity decline. Regularized regression has high potential to increase diagnostic accuracy and consistency of feature selection from multicollinear functional neuroimaging data in AD. Our findings suggest an extended network of functional alterations in AD, but the diagnostic accuracy of rs-fMRI in this multicenter setting did not reach the benchmark defined for a useful biomarker of AD. PMID:28101051

  12. Efeito da obesidade na função ventilatória Impact of obesity on ventilatory function

    Directory of Open Access Journals (Sweden)

    Perran Boran

    2007-04-01

    Full Text Available OBJETIVO: Embora a obesidade tenha sido associada ao comprometimento grave da ventilação, a maior parte da população estudada constitui-se de adultos com obesidade mórbida. Nosso objetivo foi investigar os efeitos da obesidade leve na função ventilatória de pacientes pediátricos. MÉTODOS: Estudo transversal controlado que analisou 80 pacientes (M/F: 35/45 avaliados em nosso ambulatório, com queixa de sobrepeso, sem histórico de asma ou de outras atopias, comparando-os a um grupo controle com 50 crianças de peso normal controladas para a idade e para o sexo. A média de idade dos pacientes foi de 9,7±2,5 anos (7 a 15 anos. Todos os indivíduos foram submetidos a medições antropométricas e à espirometria. A capacidade vital forçada (CVF e o volume expiratório forçado no primeiro segundo (VEF1 foram usados como medidas da função ventilatória. RESULTADOS: Não houve diferenças significativas nas VEF1%, CVF% e VEF1%/CVF% por grupo de estudo (p > 0,05. Apenas três pacientes tiveram alterações obstrutivas relatadas em seus testes de função pulmonar (dois tiveram alterações moderadamente graves e um teve alterações obstrutivas leves. Não houve correlação entre os parâmetros da função pulmonar e as medidas antropométricas. CONCLUSÃO: Esses dados mostram que os parâmetros do teste da função pulmonar em crianças com obesidade leve foram semelhantes àqueles das crianças com peso normal. As medidas antropométricas não mostraram nenhum efeito significativo nas medições espirométricas das crianças, como ocorreu nos adultos.OBJECTIVE: Although obesity was found to be associated with severe impairment of ventilation, most of the study population has been morbidly obese adults. We aimed to explore the effects of mild obesity on ventilatory function in the pediatric age group. METHODS: In a cross-sectional controlled study, 80 patients (M/F: 35/45, who were evaluated in our outpatient clinic with the complaint

  13. Regular figures

    CERN Document Server

    Tóth, L Fejes; Ulam, S; Stark, M

    1964-01-01

    Regular Figures concerns the systematology and genetics of regular figures. The first part of the book deals with the classical theory of the regular figures. This topic includes description of plane ornaments, spherical arrangements, hyperbolic tessellations, polyhedral, and regular polytopes. The problem of geometry of the sphere and the two-dimensional hyperbolic space are considered. Classical theory is explained as describing all possible symmetrical groupings in different spaces of constant curvature. The second part deals with the genetics of the regular figures and the inequalities fo

  14. Function and Regulation of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR / CRISPR Associated (Cas Systems

    Directory of Open Access Journals (Sweden)

    Peter C. Fineran

    2012-10-01

    Full Text Available Phages are the most abundant biological entities on earth and pose a constant challenge to their bacterial hosts. Thus, bacteria have evolved numerous ‘innate’ mechanisms of defense against phage, such as abortive infection or restriction/modification systems. In contrast, the clustered regularly interspaced short palindromic repeats (CRISPR systems provide acquired, yet heritable, sequence-specific ‘adaptive’ immunity against phage and other horizontally-acquired elements, such as plasmids. Resistance is acquired following viral infection or plasmid uptake when a short sequence of the foreign genome is added to the CRISPR array. CRISPRs are then transcribed and processed, generally by CRISPR associated (Cas proteins, into short interfering RNAs (crRNAs, which form part of a ribonucleoprotein complex. This complex guides the crRNA to the complementary invading nucleic acid and targets this for degradation. Recently, there have been rapid advances in our understanding of CRISPR/Cas systems. In this review, we will present the current model(s of the molecular events involved in both the acquisition of immunity and interference stages and will also address recent progress in our knowledge of the regulation of CRISPR/Cas systems.

  15. Effects of using electronic cigarettes on nicotine delivery and cardiovascular function in comparison with regular cigarettes.

    Science.gov (United States)

    Yan, X Sherwin; D'Ruiz, Carl

    2015-02-01

    The development of electronic cigarettes (e-cigs) has the potential to offer a less harmful alternative for tobacco users. This clinical study was designed to characterize e-cig users' exposure to nicotine, and to investigate the acute effects of e-cigs on the hemodynamic measurements (blood pressure and heart rate) in comparison with the effects of regular smoking. Five e-cigs and one Marlboro® cigarette were randomized for twenty-three participants under two exposure scenarios from Day 1 to Day 11: half-hour controlled administration and one hour ad lib use. The nicotine plasma concentrations after 1.5h of product use (C90) were significantly lower in the users of e-cigs than of Marlboro® cigarettes. The combination of glycerin and propylene glycol as the vehicle facilitated delivery of more nicotine than glycerin alone. The heart rate, systolic and diastolic blood pressure were significantly elevated after use of Marlboro® cigarettes, but the elevation was less after use of most of the e-cigs. Use of e-cigs had no impact on the exhaled CO levels, whereas the Marlboro® cigarette significantly increased the exhaled CO more than 8 times above the baseline. In conclusion, e-cigs could be a less harmful alternative for tobacco users. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. Function and regulation of clustered regularly interspaced short palindromic repeats (CRISPR) / CRISPR associated (Cas) systems.

    Science.gov (United States)

    Richter, Corinna; Chang, James T; Fineran, Peter C

    2012-10-19

    Phages are the most abundant biological entities on earth and pose a constant challenge to their bacterial hosts. Thus, bacteria have evolved numerous 'innate' mechanisms of defense against phage, such as abortive infection or restriction/modification systems. In contrast, the clustered regularly interspaced short palindromic repeats (CRISPR) systems provide acquired, yet heritable, sequence-specific 'adaptive' immunity against phage and other horizontally-acquired elements, such as plasmids. Resistance is acquired following viral infection or plasmid uptake when a short sequence of the foreign genome is added to the CRISPR array. CRISPRs are then transcribed and processed, generally by CRISPR associated (Cas) proteins, into short interfering RNAs (crRNAs), which form part of a ribonucleoprotein complex. This complex guides the crRNA to the complementary invading nucleic acid and targets this for degradation. Recently, there have been rapid advances in our understanding of CRISPR/Cas systems. In this review, we will present the current model(s) of the molecular events involved in both the acquisition of immunity and interference stages and will also address recent progress in our knowledge of the regulation of CRISPR/Cas systems.

  17. Regularized focusing inversion of time-lapse electrical resistivity data: an approach to parametrize the minimum gradient support functional

    Science.gov (United States)

    Nguyen, Frédéric; Hermans, Thomas

    2015-04-01

    Inversion of time-lapse resistivity data allows obtaining 'snapshots' of changes occurring in monitored systems for applications such as aquifer storage, geothermal heat exchange, site remediation or tracer tests. Based on these snapshots, one can infer qualitative information on the location and morphology of changes occurring in the subsurface but also quantitative estimates on the degree of changes in certain property such as temperature or total dissolved solid content. Analysis of these changes can provide direct insight into flow and transport and associated processes and controlling parameters. However, the reliability of the analysis is dependent on survey geometry, measurement schemes, data error, and regularization. Survey design parameters may be optimized prior to the monitoring survey. Regularization, on the other hand, may be chosen depending on available information collected during the monitoring. Common approaches consider smoothing model changes both in space and time but it is often needed to obtain a sharp temporal anomaly, for example in fractured aquifers. We here propose to use the alternative regularization approach based on minimum gradient support (MGS) (Zhdanov, 2002) for time-lapse surveys which will focus the changes in tomograms snapshots. MGS will limit the occurrences of changes in electrical resistivity but will also restrict the variations of these changes inside the different zones. A commonly encountered difficulty by practitioners in this type of regularization is the choice of an additional parameter, the so-called β, required to define the MGS functional. To the best of our knowledge, there is no commonly accepted or standard methodology to optimize the MGS parameter β. The inversion algorithm used in this study is CRTomo (Kemna 2000). It uses a Gauss-Newton scheme to iteratively minimize an objective function which consists of a data misfit functional and a model constraint functional. A univariate line search is performed

  18. On a Functional Equation Associated with (a,k-Regularized Resolvent Families

    Directory of Open Access Journals (Sweden)

    Carlos Lizama

    2012-01-01

    Full Text Available Let a∈Lloc1(ℝ+ and k∈C(ℝ+ be given. In this paper, we study the functional equation R(s(a*R(t-(a*R(sR(t=k(s(a*R(t-k(t(a*R(s, for bounded operator valued functions R(t defined on the positive real line ℝ+. We show that, under some natural assumptions on a(· and k(·, every solution of the above mentioned functional equation gives rise to a commutative (a,k-resolvent family R(t generated by Ax=lim t→0+(R(tx-k(tx/(a*k(t defined on the domain D(A:={x∈X:lim t→0+(R(tx-k(tx/(a*k(t exists in X} and, conversely, that each (a,k-resolvent family R(t satisfy the above mentioned functional equation. In particular, our study produces new functional equations that characterize semigroups, cosine operator families, and a class of operator families in between them that, in turn, are in one to one correspondence with the well-posedness of abstract fractional Cauchy problems.

  19. Regular icosahedron

    OpenAIRE

    Mihelak, Veronika

    2016-01-01

    Here are collected properties of regular icosahedron which are useful for students of mathematics or mathematics teachers who can prepare exercises for talented students in elementary or middle school. The initial section describes the basic properties of regular polyhedra: tetrahedron, cube, dodecahedron, octahedron and of course icosahedron. We have proven that there are only five regular or platonic solids and have verified Euler's polyhedron formula for them. Then we focused on selected p...

  20. Approximation of N(kappa)(infinity)-functions I : Models and Regularization

    NARCIS (Netherlands)

    Dijksma, Aad; Luger, Annemarie; Shondin, Yuri; Behrndt, J; Forster, KH; Langer, H; Trunk, C

    2009-01-01

    The class N(kappa)(infinity) consists of all generalized Nevanlinna functions N with kappa, negative squares for which the root space at, infinity of the self-adjoint relation in the minimal model (short for self-adjoint operator realization) of N contains a kappa-dimensional non-positive subspace.

  1. Dyadic Universal Functions and Simultaneous Near-Field/Far-Field Regularization of Elastodynamic Dyadic Green's Functions for 3-D Mass-Loading Analysis in Microacoustic Devices.

    Science.gov (United States)

    Baghai-Wadji, Alireza

    2016-10-01

    Assuming an infinite-domain isotropic elastic medium and a Dirac delta function vector-force excitation, [Formula: see text], spectral domain dyadic Green's functions (DGFs) G for 3-D mass-loading analysis in microacoustic devices have been constructed. Thereby, equivalent inhomogeneous plane-wave (2-D Fourier transform) and homogeneous plane-wave (3-D Fourier transform) representations, G(k1,k2) and G(k1,k2,k3) , respectively, have been obtained in closed form. The construction of G(k1,k2) follows an earlier scheme by utilizing the diagonalization of the governing equations subject to the radiation condition. Consecutively, G(k1,k2) has been employed for obtaining the associated stress distributions. The latter distributions induce novel problem-tailored expressions for η -parameterized "smeared-out" Dirac delta functions δη(x-x',y-y') . Using δη(x-x',y-y') , exponentially regularized DGFs Gη(k1,k2) have been obtained. The notion of dyadic universal functions, also introduced earlier, has been utilized to demonstrate that the exponentially regularized DGFs can in addition be regularized algebraically. Finally, the operator inversion for the construction of G(k1,k2,k3) is carried out in closed form.

  2. A quadratically regularized functional canonical correlation analysis for identifying the global structure of pleiotropy with NGS data

    Science.gov (United States)

    Zhu, Yun; Fan, Ruzong; Xiong, Momiao

    2017-01-01

    Investigating the pleiotropic effects of genetic variants can increase statistical power, provide important information to achieve deep understanding of the complex genetic structures of disease, and offer powerful tools for designing effective treatments with fewer side effects. However, the current multiple phenotype association analysis paradigm lacks breadth (number of phenotypes and genetic variants jointly analyzed at the same time) and depth (hierarchical structure of phenotype and genotypes). A key issue for high dimensional pleiotropic analysis is to effectively extract informative internal representation and features from high dimensional genotype and phenotype data. To explore correlation information of genetic variants, effectively reduce data dimensions, and overcome critical barriers in advancing the development of novel statistical methods and computational algorithms for genetic pleiotropic analysis, we proposed a new statistic method referred to as a quadratically regularized functional CCA (QRFCCA) for association analysis which combines three approaches: (1) quadratically regularized matrix factorization, (2) functional data analysis and (3) canonical correlation analysis (CCA). Large-scale simulations show that the QRFCCA has a much higher power than that of the ten competing statistics while retaining the appropriate type 1 errors. To further evaluate performance, the QRFCCA and ten other statistics are applied to the whole genome sequencing dataset from the TwinsUK study. We identify a total of 79 genes with rare variants and 67 genes with common variants significantly associated with the 46 traits using QRFCCA. The results show that the QRFCCA substantially outperforms the ten other statistics. PMID:29040274

  3. Swiss children consuming breakfast regularly have better motor functional skills and are less overweight than breakfast skippers.

    Science.gov (United States)

    Baldinger, Nina; Krebs, Andreas; Müller, Roland; Aeberli, Isabelle

    2012-04-01

    The aim of this study was to examine the associations among eating behavior, body mass index (BMI), and motor functional skills in Swiss elementary school children. In total, 656 schoolchildren, aged 7 to 10 years, participated in the study. Five different, normalized, and standardized motor function tests (sidewise jumping, tapping, standing long jump, 20-m sprint, and shuttle run) that determine the coordinative and conditional skills were carried out with each child at 1 of 4 time points (8, 9, 10, or 11 am) along with anthropometric measurements. Furthermore, all children completed a nutrition survey including different questions on their eating habits with emphasis on breakfast and the morning snack at school. Children consuming breakfast almost every day had a significantly (p breakfast only sometimes or almost never (18.2 ± 3.0 kg/m2 and 18.8 ± 3.4 kg/m2, respectively). They also reached better scores in 3 of the 5 motor function tests (standing long jump, 20-m sprint, and shuttle run, p breakfast frequency, and gender predicted only some of the outcomes. This study clearly underlines the importance of breakfast for school-aged children: Children eating breakfast almost every day had better motor functional skills and a lower BMI than children not regularly eating breakfast. The study further hints at the importance of generally healthy nutritional habits with regard to both motor functional skills and healthy weight status.

  4. Sexual functioning and commitment to their current relationship among breastfeeding and regularly cycling women in Manila, Philippines.

    Science.gov (United States)

    Escasa-Dorne, Michelle J

    2015-03-01

    This project investigates the relationship between lactation and female sexual functioning and relationship commitment among partnered women in urban Manila. Previous literature suggests that the time after giving birth is often rife with lower sexual functioning and relationship dissatisfaction. Given the important role of caregiving by multiple individuals in humans, the current cross-sectional study suggests that female sexuality may decline immediately after giving birth but then may increase afterwards. Non-cycling, breastfeeding (n = 86); cycling, breastfeeding (n = 48); and nulliparous, regularly cycling (n = 105) women were recruited from neighborhood health centers in Manila to complete questionnaires that assessed sexual functioning and relationship satisfaction, along with demographic variables. Cycling, breastfeeding women report the highest sexual functioning scores and commitment scores. Females undergoing life history trade-offs between mating effort and parenting effort during the postpartum phase may employ a strategy in which they continue investment both in their offspring and in a romantic relationship. Variations in self-reported sexual functioning, level of commitment in a relationship, and love toward her current partner may indicate that breastfeeding women engage in sexual activities as part of a relationship maintenance strategy. Cultural and life history factors will serve as a framework for the findings. The current findings suggest women in Manila may experience a post-birth increase in sexual functioning that may be higher than pre-pregnancy levels. Future studies should incorporate a longitudinal component or a memory recall on pre-pregnancy and post-birth sexual functioning levels.

  5. Regular Boardgames

    OpenAIRE

    Kowalski, Jakub; Sutowicz, Jakub; Szykuła, Marek

    2017-01-01

    We present an initial version of Regular Boardgames general game description language. This stands as an extension of Simplified Boardgames language. Our language is designed to be able to express the rules of a majority of popular boardgames including the complex rules such as promotions, castling, en passant, jump captures, liberty captures, and obligatory moves. The language describes all the above through one consistent general mechanism based on regular expressions, without using excepti...

  6. Regularized maximum correntropy machine

    KAUST Repository

    Wang, Jim Jing-Yan

    2015-02-12

    In this paper we investigate the usage of regularized correntropy framework for learning of classifiers from noisy labels. The class label predictors learned by minimizing transitional loss functions are sensitive to the noisy and outlying labels of training samples, because the transitional loss functions are equally applied to all the samples. To solve this problem, we propose to learn the class label predictors by maximizing the correntropy between the predicted labels and the true labels of the training samples, under the regularized Maximum Correntropy Criteria (MCC) framework. Moreover, we regularize the predictor parameter to control the complexity of the predictor. The learning problem is formulated by an objective function considering the parameter regularization and MCC simultaneously. By optimizing the objective function alternately, we develop a novel predictor learning algorithm. The experiments on two challenging pattern classification tasks show that it significantly outperforms the machines with transitional loss functions.

  7. Adaptive regularization

    DEFF Research Database (Denmark)

    Hansen, Lars Kai; Rasmussen, Carl Edward; Svarer, C.

    1994-01-01

    Regularization, e.g., in the form of weight decay, is important for training and optimization of neural network architectures. In this work the authors provide a tool based on asymptotic sampling theory, for iterative estimation of weight decay parameters. The basic idea is to do a gradient descent...... in the estimated generalization error with respect to the regularization parameters. The scheme is implemented in the authors' Designer Net framework for network training and pruning, i.e., is based on the diagonal Hessian approximation. The scheme does not require essential computational overhead in addition...

  8. Longitudinal functional connectivity changes correlate with mood improvement after regular exercise in a dose-dependent fashion.

    Science.gov (United States)

    Tozzi, Leonardo; Carballedo, Angela; Lavelle, Grace; Doolin, Kelly; Doyle, Myles; Amico, Francesco; McCarthy, Hazel; Gormley, John; Lord, Anton; O'Keane, Veronica; Frodl, Thomas

    2016-04-01

    Exercise increases wellbeing and improves mood. It is however unclear how these mood changes relate to brain function. We conducted a randomized controlled trial investigating resting-state modifications in healthy adults after an extended period of aerobic physical exercise and their relationship with mood improvements. We aimed to identify novel functional networks whose activity could provide a physiological counterpart to the mood-related benefits of exercise. Thirty-eight healthy sedentary volunteers were randomised to either the aerobic exercise group of the study or a control group. Participants in the exercise group attended aerobic sessions with a physiotherapist twice a week for 16 weeks. Resting-state modifications using magnetic resonance imaging were assessed before and after the programme and related to mood changes. An unbiased approach using graph metrics and network-based statistics was adopted. Exercise reduced mood disturbance and improved emotional wellbeing. It also induced a decrease in local efficiency in the parahippocampal lobe through strengthening of the functional connections from this structure to the supramarginal gyrus, precentral area, superior temporal gyrus and temporal pole. Changes in mood disturbance following exercise were correlated with those in connectivity between parahippocampal gyrus and superior temporal gyrus as well as with the amount of training. No changes were detected in the control group. In conclusion, connectivity from the parahippocampal gyrus to motor, sensory integration and mood regulation areas was strengthened through exercise. These functional changes might be related to the benefits of regular physical activity on mood. © 2016 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  9. Radial-basis-function level-set-based regularized Gauss-Newton-filter reconstruction scheme for dynamic shape tomography.

    Science.gov (United States)

    Naik, Naren; Beatson, Rick; Eriksson, Jerry

    2014-10-10

    The dynamic reconstruction problem in tomographic imaging is encountered in several applications, such as species determination, the study of blood flow through arteries/veins, motion compensation in medical imaging, and process tomography. The reconstruction method of choice is the Kalman filter and its variants, which, however, are faced by issues of filter tuning. In addition, since the time-propagation models of physical parameters are typically very complex, most of the time, a random walk model is considered. For geometric deformations, affine models are typically used. In our work, with the objectives of minimizing tuning issues and reconstructing time-varying geometrically deforming features of interest with affine in addition to pointwise-normal scaling motions, a novel level-set-based reconstruction scheme for ray tomography is proposed for shape and electromagnetic parameters using a regularized Gauss-Newton-filter-based scheme. We use an implicit Hermite-interpolation-based radial basis function representation of the zero level set corresponding to the boundary curve. Another important contribution of the paper is an evaluation of the shape-related Frechet derivatives that does not need to evaluate the pointwise Jacobian (the ray-path matrix in our ray-tomography problem). Numerical results validating the formulation are presented for a straight ray-based tomographic reconstruction. To the best of our knowledge, this paper presents the first tomographic reconstruction results in these settings.

  10. Diversity, evolution, and functionality of clustered regularly interspaced short palindromic repeat (CRISPR) regions in the fire blight pathogen Erwinia amylovora.

    Science.gov (United States)

    Rezzonico, Fabio; Smits, Theo H M; Duffy, Brion

    2011-06-01

    The clustered regularly interspaced short palindromic repeat (CRISPR)/Cas system confers acquired heritable immunity against mobile nucleic acid elements in prokaryotes, limiting phage infection and horizontal gene transfer of plasmids. In CRISPR arrays, characteristic repeats are interspersed with similarly sized nonrepetitive spacers derived from transmissible genetic elements and acquired when the cell is challenged with foreign DNA. New spacers are added sequentially and the number and type of CRISPR units can differ among strains, providing a record of phage/plasmid exposure within a species and giving a valuable typing tool. The aim of this work was to investigate CRISPR diversity in the highly homogeneous species Erwinia amylovora, the causal agent of fire blight. A total of 18 CRISPR genotypes were defined within a collection of 37 cosmopolitan strains. Strains from Spiraeoideae plants clustered in three major groups: groups II and III were composed exclusively of bacteria originating from the United States, whereas group I generally contained strains of more recent dissemination obtained in Europe, New Zealand, and the Middle East. Strains from Rosoideae and Indian hawthorn (Rhaphiolepis indica) clustered separately and displayed a higher intrinsic diversity than that of isolates from Spiraeoideae plants. Reciprocal exclusion was generally observed between plasmid content and cognate spacer sequences, supporting the role of the CRISPR/Cas system in protecting against foreign DNA elements. However, in several group III strains, retention of plasmid pEU30 is inconsistent with a functional CRISPR/Cas system.

  11. Morphological and functional alterations of female reproduction after regular exposure of bamboo shoots of North East India

    Directory of Open Access Journals (Sweden)

    Deotima Sarkar

    2017-07-01

    Full Text Available Objective: To evaluate the effect of daily consumption of bamboo shoots (BS on the morphological features and functional status of the female reproductive system in adult with respect to thyroid. Methods: Adult female rats were divided into control and experimental groups of six each. Control group was given normal diet while experimental group was fed BS by 1/3rd replacement of 180 g of their food i.e. 60 g of BS containing 35 g of goitrogens of cyanogenic origin such that each rat likely consumed 6 mg/100 g of body weight per day for a period of 45 d. Morphological features like changes in body weight and organ weight were noted. Key steroidogenic enzyme levels viz Δ5 3β hydroxysteroid dehydrogenase (HSD and 17β HSD along with serum estradiol, estriol and progesterone levels were measured. Estrous cyclicity of the animals monitored regularly followed by histological analysis of thyroid, ovary and uterus at the end of experimentation. Results: Increase in body weight, thyroid gland weight and thyroid stimulating hormone, decrease in serum triiodothyronine and thyroxine, a decrease in ovarian as well as uterine weight and the activity of steroidogenic enzymes Δ5 3β HSD and 17β HSD along with diminished serum estradiol, estriol and progesterone levels were noted; while histological plates showed prominent degenerative changes in both the ovary and uterus. Estrous cyclicity of the treated animals were irregular and almost stopped at diestrous stage of the cycle in the latter stage of the treatment as compared to control. Conclusions: Overall results indicates that BS rich in cyanogenic constituents induces biochemical hypothyroidism in the experimental animals that acts in corroboration to cause morphological and functional alteration of reproductive organs indicating its likely impact in fertility on continued use.

  12. Common conversion point stacking of receiver functions versus passive-source reverse time migration and wavefield regularization

    Science.gov (United States)

    Shang, Xuefeng; de Hoop, Maarten V.; van der Hilst, Robert D.

    2017-05-01

    We demonstrate with synthetic and field data that with sufficiently dense sampling wave-equation-based methods such as reverse time migration (RTM), implicitly forming array receiver functions (ARFs), perform better resolution wise than migration of common conversion point (CCP) stacks of traditional receiver functions. However, even with modern array deployments the sampling requirement is typically not met for teleseismic (earthquake) data. To enable RTM imaging with sparsely (and irregularly) sampled wavefields at the surface, we use an intermediate reconstruction based on sparsity promoting optimization using a curvelet (or wave packet) representation of the data, as an important and necessary pre-processing step. To suppress artefacts, the curvelet coefficients are constrained to represent the range of known directions present in the data. We show that our proposed pre-processing procedure (which may be viewed as generating 'missing' traces) can produce artefact-free data for RTM even if only 20 per cent of necessary data are available in the original data set. With synthetic data, we also demonstrate that if the sampling criteria is not met, CCP can produce results that are superior over wave-equation methods such as RTM. As a proof-of-concept with field data, we image the structure of the crust beneath the Himalayas with passive-source RTM of teleseismic data from Hi-CLIMB project. For Hi-CLIMB data, the CCP and RTM results are similar because sampling is still too sparse for RTM and the structure is simple enough for successful CCP. Both results are improved by wavefield regularization and reveal that the Moho is continuous beneath most of the array, and not fragmented as suggested by some earlier studies.

  13. Regular physical activity modifies smoking-related lung function decline and reduces risk of chronic obstructive pulmonary disease: a population-based cohort study

    DEFF Research Database (Denmark)

    Garcia-Aymerich, J; Lange, Peter; Benet, M

    2007-01-01

    RATIONALE: We have previously reported that regular physical activity reduces risk of chronic obstructive pulmonary disease (COPD) exacerbation. We hypothesized that higher levels of regular physical activity could reduce the risk of COPD by modifying smoking-related lung function decline....... OBJECTIVE: To estimate the longitudinal association between regular physical activity and FEV(1) and FVC decline and COPD risk. METHODS: A population-based sample (n = 6,790) was recruited and assessed with respect to physical activity, smoking, lung function, and other covariates, in Copenhagen in 1981......-1983, and followed until 1991-1994. Mean level of physical activity between baseline and follow-up was classified into "low," "moderate," and "high." FEV(1) and FVC decline rates were expressed as milliliters per year. COPD was defined as FEV(1)/FVC physical activity and FEV...

  14. Regular polytopes

    CERN Document Server

    Coxeter, H S M

    1973-01-01

    Polytopes are geometrical figures bounded by portions of lines, planes, or hyperplanes. In plane (two dimensional) geometry, they are known as polygons and comprise such figures as triangles, squares, pentagons, etc. In solid (three dimensional) geometry they are known as polyhedra and include such figures as tetrahedra (a type of pyramid), cubes, icosahedra, and many more; the possibilities, in fact, are infinite! H. S. M. Coxeter's book is the foremost book available on regular polyhedra, incorporating not only the ancient Greek work on the subject, but also the vast amount of information

  15. Development of a local size hierarchy causes regular spacing of trees in an even-aged Abies forest: analyses using spatial autocorrelation and the mark correlation function.

    Science.gov (United States)

    Suzuki, Satoshi N; Kachi, Naoki; Suzuki, Jun-Ichirou

    2008-09-01

    During the development of an even-aged plant population, the spatial distribution of individuals often changes from a clumped pattern to a random or regular one. The development of local size hierarchies in an Abies forest was analysed for a period of 47 years following a large disturbance in 1959. In 1980 all trees in an 8 x 8 m plot were mapped and their height growth after the disturbance was estimated. Their mortality and growth were then recorded at 1- to 4-year intervals between 1980 and 2006. Spatial distribution patterns of trees were analysed by the pair correlation function. Spatial correlations between tree heights were analysed with a spatial autocorrelation function and the mark correlation function. The mark correlation function was able to detect a local size hierarchy that could not be detected by the spatial autocorrelation function alone. The small-scale spatial distribution pattern of trees changed from clumped to slightly regular during the 47 years. Mortality occurred in a density-dependent manner, which resulted in regular spacing between trees after 1980. The spatial autocorrelation and mark correlation functions revealed the existence of tree patches consisting of large trees at the initial stage. Development of a local size hierarchy was detected within the first decade after the disturbance, although the spatial autocorrelation was not negative. Local size hierarchies that developed persisted until 2006, and the spatial autocorrelation became negative at later stages (after about 40 years). This is the first study to detect local size hierarchies as a prelude to regular spacing using the mark correlation function. The results confirm that use of the mark correlation function together with the spatial autocorrelation function is an effective tool to analyse the development of a local size hierarchy of trees in a forest.

  16. REGULAR OBSERVATION OF CHILDREN WITH BRONCHIAL ASTHMA BY ALLERGOLOGIST AND ITS INFLUENCE ON CLINICAL AND FUNCTIONAL PARAMETERS OF THE DISEASE AND CONSUMPTION OF HEALTHCARE RESOURCES

    Directory of Open Access Journals (Sweden)

    I.P. Artyukhov

    2011-01-01

    Full Text Available In real practice, treatment of patients with bronchial asthma (BA is accompanied by unreasonable increase of healthcare resources consumption because of unplanned visits to the doctor due to health worsening, hospital treatment of exacerbations and emergency calls. Objective: to evaluate an effectiveness of children’s with bronchial asthma observations by allergologist. Methods: the dynamics of clinical and functional signs and frequency of emergency claims was analyzed in 115 children with BA who were observed by allergologist once in 3 months during one year. Results: in 3 months of regular observation by allergologist the number of children with day and night symptoms of BA and patients with daily rescue use of short-acting 2-agonists decreased, there were fewer children with limitations of physical activity. The number of patients with normal FEV1 increased in 6 months. Regular observation with allergologist resulted in reduction of number of patients with exacerbations and hospitalizations, shortening of acute period of BA and hospital stay, decreasing of emergency claims rate compared to those who were observed by GPs. Conclusion: regular observation by allergologist once in 3 months results in stabilization of clinical and functional state in patients with BA and decreases the consumption of emergency care resources.Key words: children, bronchial asthma, allergologist, clinical and functional state, healthcare resources.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2011; 10 (3: 55–59

  17. UNFOLDED REGULAR AND SEMI-REGULAR POLYHEDRA

    Directory of Open Access Journals (Sweden)

    IONIŢĂ Elena

    2015-06-01

    Full Text Available This paper proposes a presentation unfolding regular and semi-regular polyhedra. Regular polyhedra are convex polyhedra whose faces are regular and equal polygons, with the same number of sides, and whose polyhedral angles are also regular and equal. Semi-regular polyhedra are convex polyhedra with regular polygon faces, several types and equal solid angles of the same type. A net of a polyhedron is a collection of edges in the plane which are the unfolded edges of the solid. Modeling and unfolding Platonic and Arhimediene polyhedra will be using 3dsMAX program. This paper is intended as an example of descriptive geometry applications.

  18. Functional status, physical activity level, and exercise regularity in patients with fibromyalgia after Multidisciplinary treatment: retrospective analysis of a randomized controlled trial.

    Science.gov (United States)

    Salvat, I; Zaldivar, P; Monterde, S; Montull, S; Miralles, I; Castel, A

    2017-03-01

    Multidisciplinary treatments have shown to be effective for fibromyalgia. We report detailed functional outcomes of patients with fibromyalgia who attended a 3-month Multidisciplinary treatment program. The hypothesis was that patients would have increased functional status, physical activity level, and exercise regularity after attending this program. We performed a retrospective analysis of a randomized, simple blinded clinical trial. The inclusion criteria consisted of female sex, a diagnosis of fibromyalgia, age 18-60  and 3-8 years of schooling. Measures from the Fibromyalgia Impact Questionnaire (FIQ) and the COOP/WONCA Functional Health Assessment Charts (WONCA) were obtained before and at the end of the treatment and at 3-, 6-, and 12-month follow-ups. Patients recorded their number of steps per day with pedometers. They performed the six-minute walk test (6 MW) before and after treatment. In total, 155 women participated in the study. Their median (interquartile interval) FIQ score was 68.0 (53.0-77.0) at the beginning of the treatment, and the difference between the Multidisciplinary and Control groups was statistically and clinically significant in all of the measures (except the 6-month follow-up). The WONCA charts showed significant clinical improvements in the Multidisciplinary group, with physical fitness in the normal range across almost all values. In that group, steps/day showed more regularity, and the 6 MW results showed improvement of -33.00 (-59.8 to -8.25) m, and the differences from the Control group were statistically significant. The patients who underwent the Multidisciplinary treatment had improved functional status, physical activity level, and exercise regularity. The functional improvements were maintained 1 year after treatment completion.

  19. REGULARIZED FUNCTIONAL PRINCIPAL COMPONENT ANALYSIS AND AN APPLICATION ON THE SHARE PRICES OF THE COMPANIES BELONGING TO THE ISE-30 INDEX

    Directory of Open Access Journals (Sweden)

    İSTEM KÖYMEN KESER

    2013-06-01

    Full Text Available The objective of the Functional Data Analysis techniques is to study such type of data which consist of observed functions or curves evaluated at a finite subset of some real interval.   Techniques in Functional Data Analysis can be used to study the variation in a random sample of real functions, xi(t, i=1, 2, …, N and their derivatives. In practice, these functions are often a consequence of a preliminary smoothing process applied to discrete data and in this work, Spline Smoothing Methods are used.  As the number of functions and the number of observation points increases, it would be difficult to handle the functions  altogether. In order to overcome this complexity, we utilize Functional and Regularized Functional Principal Component Analyses where a high percentage of total variation  could be accounted for with only a few component functions.  Finally, an application on the daily closing data for the share prices of the companies belonging to the ISE-30 index is also given.

  20. Online co-regularized algorithms

    NARCIS (Netherlands)

    Ruijter, T. de; Tsivtsivadze, E.; Heskes, T.

    2012-01-01

    We propose an online co-regularized learning algorithm for classification and regression tasks. We demonstrate that by sequentially co-regularizing prediction functions on unlabeled data points, our algorithm provides improved performance in comparison to supervised methods on several UCI benchmarks

  1. Regular physical activity modifies smoking-related lung function decline and reduces risk of chronic obstructive pulmonary disease: a population-based cohort study

    DEFF Research Database (Denmark)

    Garcia-Aymerich, J; Lange, Peter; Benet, M

    2007-01-01

    . OBJECTIVE: To estimate the longitudinal association between regular physical activity and FEV(1) and FVC decline and COPD risk. METHODS: A population-based sample (n = 6,790) was recruited and assessed with respect to physical activity, smoking, lung function, and other covariates, in Copenhagen in 1981......(1) and FVC decline, and COPD incidence, were obtained using linear and logistic regression, respectively. RESULTS: Active smokers with moderate and high physical activity had a reduced FEV(1) and FVC decline compared with those with low physical activity (relative change of +2.6 and +4.8 ml...

  2. THE EFFECTS OF LONG-TERM REGULAR EXERCISE ON ENDOTHELIAL FUNCTIONS, INFLAMMATORY AND THROMBOTIC ACTIVITY IN MIDDLE-AGED, HEALTHY MEN

    Directory of Open Access Journals (Sweden)

    Metin Ergün

    2006-06-01

    Full Text Available As studying with population carrying no classical cardiovascular risk factors seems to be an advantage in isolating effects of regular exercise on endothelial functions, inflammatory and thrombotic activity; the present study was designed to evaluate the clear effects of long-term regular exercise in middle-aged, healthy men. A total of 32 regularly exercising (three times per week, 12.8 ± 6.8 years men (Group I, mean age = 53.2 ± 6. 1 yrs and 32 sex- and age-matched sedentary subjects (Group II, mean age = 51.0 ± 7.7 yrs were involved in the study. All participants were non-smokers and with no history of hypertension and diabetes. During one day preceding tests, the subjects refrained from training and maintained their normal diet. In all subjects, body mass index (BMI, percentage of body fat (% BF and maximal oxygen uptake (VO2max were calculated. Serum uric acid, glucose, HbA1c, lipids, high-sensitive C-reactive protein (hs-CRP, fibrinogen levels, white blood cell (WBC and platelet count were measured. Resting heart rates and blood pressures were recorded and standard exercise stress test was applied using the modified Bruce protocol. Flow-mediated and nitrate-induced dilatation (FMD and NID of the brachial artery and carotid intima-media thickness (cIMT were evaluated as markers of endothelial functions and early atherosclerosis. Mean BMI, % BF, systolic and diastolic blood pressures, WBC and platelet count, HbA1c, total and LDL cholesterol, hs-CRP and fibrinogen levels were similar between the groups. Group I had significantly lower serum glucose, uric acid and triglyceride (p < 0.05, p < 0.005 and p < 0.05, respectively and higher HDL cholesterol levels (p < 0.0001 than in Group II. FMD values were significantly higher in Group I than in Group II (p < 0.005 while there were no significant differences in NID and cIMT measures between the groups. VO2max and cIMT showed a negative correlation in Group I (r = -0.463, p < 0.0001. Negative

  3. Sparse structure regularized ranking

    KAUST Repository

    Wang, Jim Jing-Yan

    2014-04-17

    Learning ranking scores is critical for the multimedia database retrieval problem. In this paper, we propose a novel ranking score learning algorithm by exploring the sparse structure and using it to regularize ranking scores. To explore the sparse structure, we assume that each multimedia object could be represented as a sparse linear combination of all other objects, and combination coefficients are regarded as a similarity measure between objects and used to regularize their ranking scores. Moreover, we propose to learn the sparse combination coefficients and the ranking scores simultaneously. A unified objective function is constructed with regard to both the combination coefficients and the ranking scores, and is optimized by an iterative algorithm. Experiments on two multimedia database retrieval data sets demonstrate the significant improvements of the propose algorithm over state-of-the-art ranking score learning algorithms.

  4. The effect of on-line hemodiafiltration on improving the cardiovascular function parameters in children on regular dialysis

    Directory of Open Access Journals (Sweden)

    Fatina I Fadel

    2015-01-01

    Full Text Available The cardiovascular disease is an important cause of morbidity and accounts for almost 50% of deaths in patients undergoing maintenance dialysis. Many harmful molecules of the uremic milieu, such as the middle molecules, are difficult to remove by conventional hemodialysis (HD. On-line hemodiafiltration (OL-HDF can achieve a considerable clearance of middle molecules and, together with its sterile ultrapure infusate, may have favorable effects on inflammation and cardiovascular complications. We aimed in this study to assess the effect of OL-HDF on improving the chronic inflammatory state associated with chronic kidney disease and the possible impact of these changes on myocardial function in chronic HD children. Thirty pediatric patients [12 (40% males and 18 (60% females with a mean age of 11.3 ± 3.2 years] on conventional HD for at least six months were switched to OL-HDF for six months. Variables for comparison at the end of each period included the levels of serum C-reactive protein and Kt/V as well as electrocardiography and echocardiographic measurements, including left ventricular mass index (LVMI. On changing from HD to OL-HDF, there was a significant decrease in hs-CRP (from 7.9 ± 8.9 to 3.4 ± 3 μ g/mL (P = 0.01 and frequency of diastolic dysfunction (P = 0.04, while systolic function (FS and EF improved significantly (P = 0.007 and 0.05, respectively, while LVMI did not change. We conclude that OL-HDF was well tolerated in children with improvement of the systolic function of the myocardium and the overall frequency of diastolic dysfunction.

  5. The relationship between regular second-hand smoke exposure at home and indictors of lung function in healthy school boys in Khartoum.

    Science.gov (United States)

    Merghani, Tarig Hakim; Saeed, Amal M

    2013-09-01

    Exposure to second-hand tobacco smoke at home has been linked to many complications, including impaired lung ventilatory function; however, there is great variation in intensity of this complication between individuals of different countries. The aim of this study was to determine relationship between regular second-hand smoke exposure at home and the spirometric derived values forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), forced expiratory flow 50% and peak expiratory flow rate in healthy school boys in Khartoum. A total of 135 male school pupils were selected randomly from three governmental primary schools for boys in Khartoum. Inclusion criteria were healthy school pupil, 9-14 years old, not active smoker, either exposed regularly to cigarette smoke at home since birth or not exposed to cigarette smoke or any other type of smoke inside or outside the house. All spirometric measurements were performed using Clement Clarke All-flow Spirometer. 69 school pupils were exposed regularly to second-hand smoke at home, whereas 66 pupils were not. Fathers were responsible for 67.5% of second-hand smoke at home; relatives for 30% and mothers for 2.5%. Mean FVC (± SD) was 2.21 ± 0.57 l for the exposed pupils and 2.41 ± 0.35 l for the non-exposed, showing reduction by about 8%. Mean FEV1 (mean ± SD) was 2.03 ± 0.46 l for the exposed and 2.20 ± 0.42 l for the non-exposed, indicating reduction by about 7%. The differences between the two groups were statistically significant (psecond-hand smoke exposure at home causes significant reduction in FVC and FEV1 by about 7%-8% in school pupils in Khartoum.

  6. The prevalence of personality disorders in psychiatric outpatients with borderline intellectual functioning: Comparison with outpatients from regular mental health care and outpatients with mild intellectual disabilities.

    Science.gov (United States)

    Wieland, Jannelien; Van Den Brink, Annemarie; Zitman, Frans G

    2015-01-01

    There is little research on the subject of personality disorder (PD) in individuals with borderline intellectual functioning (BIF). Unlike in most countries, in the Netherlands, patients with BIF are eligible for specialized mental health care. This offers the unique possibility of examining the rates of PDs in patients, who in other countries are treated relatively invisibly in regular mental health care. To compare, in a naturalistic setting, the frequency of PD diagnoses in outpatients with BIF with outpatients from regular mental health care and outpatients with mild ID. We compared the rates of all DSM-IV-TR axis II PDs in outpatients with BIF (BIF group; n = 235) with rates of the same disorders in outpatients from regular mental health care (RMHC group; n = 1026) and outpatients with mild intellectual disability (ID) (mild ID group; n = 152) in a naturalistic cross-sectional anonymized medical chart review. Over half of the patients with BIF (52.8%) were diagnosed with a PD, compared with one in five in the RMHC group (19.3%) and one in three of the mild ID group (33.6%). All PD diagnoses, except for cluster A PDs and histrionic PDs, were most frequently diagnosed in the BIF group. PD NOS and borderline PD were the most frequently diagnosed PDs in BIF. The majority of PD patients had one or more comorbid axis I disorder. There is a high frequency of PD diagnoses in BIF outpatients in daily clinical practice. In anticipation of further scientific research, results suggest that PDs should not be overlooked in patients with BIF.

  7. Os efeitos dos aparelhos funcionais sobre a dimensão transversal da maxila e mandíbula The effects of functional appliances in the maxilla and mandibular transverse dimension

    Directory of Open Access Journals (Sweden)

    Adriano Marotta Araújo

    2005-04-01

    Full Text Available Enquanto os efeitos dos aparelhos ortopédicos funcionais sobre as dimensões ântero-posterior e vertical vêm sendo amplamente estudados, o efeito sobre a dimensão transversal é um campo limitado e pouco explorado. A presença de escudos vestibulares, a pressão muscular, tração periostal e o reposicionamento lingual são alguns dos tópicos que podem influenciar o crescimento transversal da maxila e mandíbula. Vários estudos mostram uma alteração transversal dos arcos dentários, como resposta da terapia com o aparelho funcional. Baseado em uma revisão sistemática da literatura esse trabalho teve como objetivo: 1 avaliar os mecanismo de ação dos aparelhos e a influência sobre a dimensão transversal e 2 resumir os efeitos clínicos de diferentes aparelhos funcionais sobre a dimensão transversal.While the effects of functional appliances on the antero-posterior and vertical dimensions have been well studied, the literature pertaining to their transverse effects is limited and has not previously been synthesized. Buccal muscular pressure, periostal traction, and tongue repositioning are some of the proposed mechanisms by which transverse jaw dimensions could change during treatment. Various studies have reported transverse dental arch changes, but the effects appear to be dependent on the functional appliance used. Based on a systematic review of the literature, the purpouse of this paper are: 1 evaluated the proposed mechanisms that influence the transverse dimensions during treatment and 2 summarizes the clinical effects of various functional appliances on transverse jaw dimensions.

  8. An exploratory study of the effect of regular aquatic exercise on the function of neutrophils from women with fibromyalgia: role of IL-8 and noradrenaline.

    Science.gov (United States)

    Bote, M E; García, J J; Hinchado, M D; Ortega, E

    2014-07-01

    Fibromyalgia (FM) syndrome is associated with elevated systemic inflammatory and stress biomarkers, and an elevated innate cellular response mediated by monocytes and neutrophils. Exercise is accepted as a good non-pharmacological therapy for FM. We have previously found that regular aquatic exercise decreases the release of inflammatory cytokines by monocytes from FM patients. However, its effects on the functional capacity of neutrophils have not been studied. The aim of the present exploratory study was to evaluate, in 10 women diagnosed with FM, the effect of an aquatic exercise program (8months, 2sessions/week, 60min/session) on their neutrophils' function (phagocytic process), and on IL-8 and NA as potential inflammatory and stress mediators, respectively. A control group of 10 inactive FM patients was included in the study. After 4months of the exercise program, no significant changes were observed in neutrophil function (chemotaxis, phagocytosis, or fungicidal capacity) or in IL-8 and NA. However, at the end of the exercise program (8months), a neuro-immuno-endocrine adaptation was observed, manifested by a significant decrease to values below those in the basal state in neutrophil chemotaxis, IL-8, and NA. No significant seasonal changes in these parameters were observed during the same period in the group of non-exercised FM patients. After the 8months of the exercise program, the FM patients had lower concentrations of IL-8 and NA together with reduced chemotaxis of neutrophils compared with the values determined in the same month in the control group of non-exercised FM women. These results suggest that "anti-inflammatory" and "anti-stress" adaptations may be contributing to the symptomatic benefits that have been attributed to regular aquatic exercise in FM syndrome, as was corroborated in the present study by the scores on the Fibromyalgia Impact Questionnaire. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)

    DEFF Research Database (Denmark)

    Lintner, Nathanael G; Kerou, Melina; Brumfield, Susan K

    2011-01-01

    In response to viral infection, many prokaryotes incorporate fragments of virus-derived DNA into loci called clustered regularly interspaced short palindromic repeats (CRISPRs). The loci are then transcribed, and the processed CRISPR transcripts are used to target invading viral DNA and RNA....... The Escherichia coli "CRISPR-associated complex for antiviral defense" (CASCADE) is central in targeting invading DNA. Here we report the structural and functional characterization of an archaeal CASCADE (aCASCADE) from Sulfolobus solfataricus. Tagged Csa2 (Cas7) expressed in S. solfataricus co-purifies with Cas5......a-, Cas6-, Csa5-, and Cas6-processed CRISPR-RNA (crRNA). Csa2, the dominant protein in aCASCADE, forms a stable complex with Cas5a. Transmission electron microscopy reveals a helical complex of variable length, perhaps due to substoichiometric amounts of other CASCADE components. A recombinant Csa2...

  10. Protein radial distribution function (P-RDF) and Bayesian-Regularized Genetic Neural Networks for modeling protein conformational stability: chymotrypsin inhibitor 2 mutants.

    Science.gov (United States)

    Fernández, Michael; Caballero, Julio; Fernández, Leyden; Abreu, José Ignacio; Garriga, Miguel

    2007-11-01

    Development of novel computational approaches for modeling protein properties is a main goal in applied Proteomics. In this work, we reported the extension of the radial distribution function (RDF) scores formalism to proteins for encoding 3D structural information with modeling purposes. Protein-RDF (P-RDF) scores measure spherical distributions on protein 3D structure of 48 amino acids/residues properties selected from the AAindex data base. P-RDF scores were tested for building predictive models of the change of thermal unfolding Gibbs free energy change (DeltaDeltaG) of chymotrypsin inhibitor 2 upon mutations. In this sense, an ensemble of Bayesian-Regularized Genetic Neural Networks (BRGNNs) yielded an optimum nonlinear model for the conformational stability. The ensemble predictor described about 84% and 70% variance of the data in training and test sets, respectively.

  11. Similar effects of leucine rich and regular dairy products on muscle mass and functions of older polymyalgia rheumatica patients: a randomized crossover trial.

    Science.gov (United States)

    Björkman, M P; Pilvi, T K; Kekkonen, R A; Korpela, R; Tilvis, R S

    2011-06-01

    Leucine-rich milk and whey proteins have been suggested for prevention of age related loss of muscle mass and strength i.e. sarcopenia. The effects of milk protein supplementation and low intensity home based physical exercise on body composition and muscle functions were investigated. A randomized double blind crossover trial. Community dwelling members of Helsinki rheumatoid association. Older people (N=47, mean age 69.5 years) suffering from polymyalgia rheumatica. Patients performed as many stand ups as possible twice a day after which they ingested a regular (Control) or a whey protein enriched dairy product with high leucine content (Test). The 8-week intervention periods were separated by a 4-week wash-out. Body composition was measured by dual x-ray absorptiometry and muscle functions by hand grip strength, force platform countermovement jump performance, chair stand test, and walking speed. The 16-week home-based post-exercise supplementation resulted in a 1.8% increase (p = 0.052) in lower limb muscle mass. Walking speed (+5.3%, p = 0.007) and chair stand test performance (-12.2 %, p supplements, but the test supplement tended to prevent accumulation of body fat. A low intensity home based exercise program combined with post-exercise milk protein supplementation is feasible despite some gastrointestinal complaints and seems effective in improving the muscle mass and functions of older persons with a inflammatory disease. Further studies are needed to establish, whether and to what extent the use of leucine-enriched whey products prevent or treat age-associated sarcopenia and whether they are superior to the present commercial milk products.

  12. Regular Expression Pocket Reference

    CERN Document Server

    Stubblebine, Tony

    2007-01-01

    This handy little book offers programmers a complete overview of the syntax and semantics of regular expressions that are at the heart of every text-processing application. Ideal as a quick reference, Regular Expression Pocket Reference covers the regular expression APIs for Perl 5.8, Ruby (including some upcoming 1.9 features), Java, PHP, .NET and C#, Python, vi, JavaScript, and the PCRE regular expression libraries. This concise and easy-to-use reference puts a very powerful tool for manipulating text and data right at your fingertips. Composed of a mixture of symbols and text, regular exp

  13. Extensions of the ring of continuous functions generated by regular, countably-divisible, complete rings of quotients, and their corresponding pre-images

    Science.gov (United States)

    Zakharov, V. K.

    1995-08-01

    In this article we consider metaregular and countably-divisible extensions generated by a regular quotient ring of the ring of continuous functions in the spirit of Fine-Gillman-Lambek. The corresponding pre-images of maximal ideals are considered in connection with these extensions. These pre-images are called small absolutes and a-nonconnected coverings. To characterize these structures a new topological structure is introduced for Aleksandrov spaces with a precovering. In this connection we introduce the notion of a non-connected covering of step type. In the first part of the article we give a characterization of a small absolute as a relatively countably non-connected covering (Theorem 1). We also give a description of the absolute (Theorem 2) and of Aleksandrov pre-images of maximal ideals of Hausdorff-Sierpinski ring extensions (Theorem 3). In the second part we give a characterization of an a-non-connected pre-image as an absolutely countably non-connected covering (Theorem 4). Descriptions are also given of Baire and Borel pre-images generated by the classical Baire and Borel measurable extensions (Theorem 5).

  14. Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE).

    Science.gov (United States)

    Lintner, Nathanael G; Kerou, Melina; Brumfield, Susan K; Graham, Shirley; Liu, Huanting; Naismith, James H; Sdano, Matthew; Peng, Nan; She, Qunxin; Copié, Valérie; Young, Mark J; White, Malcolm F; Lawrence, C Martin

    2011-06-17

    In response to viral infection, many prokaryotes incorporate fragments of virus-derived DNA into loci called clustered regularly interspaced short palindromic repeats (CRISPRs). The loci are then transcribed, and the processed CRISPR transcripts are used to target invading viral DNA and RNA. The Escherichia coli "CRISPR-associated complex for antiviral defense" (CASCADE) is central in targeting invading DNA. Here we report the structural and functional characterization of an archaeal CASCADE (aCASCADE) from Sulfolobus solfataricus. Tagged Csa2 (Cas7) expressed in S. solfataricus co-purifies with Cas5a-, Cas6-, Csa5-, and Cas6-processed CRISPR-RNA (crRNA). Csa2, the dominant protein in aCASCADE, forms a stable complex with Cas5a. Transmission electron microscopy reveals a helical complex of variable length, perhaps due to substoichiometric amounts of other CASCADE components. A recombinant Csa2-Cas5a complex is sufficient to bind crRNA and complementary ssDNA. The structure of Csa2 reveals a crescent-shaped structure unexpectedly composed of a modified RNA-recognition motif and two additional domains present as insertions in the RNA-recognition motif. Conserved residues indicate potential crRNA- and target DNA-binding sites, and the H160A variant shows significantly reduced affinity for crRNA. We propose a general subunit architecture for CASCADE in other bacteria and Archaea.

  15. Regular simplex refinement by regular simplices

    NARCIS (Netherlands)

    Casado, L.G.; Tóth, B.G.; Hendrix, E.M.T.; García, I.

    2014-01-01

    A naturalway to define branching in Branch-and-Bound for blending problemis to do bisection. The disadvantage of bisectioning is that partition sets are in general irregular. A regular simplex with fixed orientation can be determined by its center and size, allowing storage savings in a Branchand-

  16. Effect of Bacillus thuringiensis on microbial functional groups in sorghum rhizosphere Efeito do Bacillus thuringiensis sobre grupos funcionais de microrganismos na rizosfera de sorgo

    Directory of Open Access Journals (Sweden)

    Carlos Brasil

    2006-05-01

    Full Text Available The objective of this work was to assess the effect of two strains of Bacillus thuringiensis var. kurstaki on sorghum rhizosphere microorganisms. The strains were HD1, that produces the bioinsecticidal protein, and 407, that is a mutant non-producer. The strains do not influence microbial population, but reduce plant growth and improve mycorrhizal colonization and free living fixing N2 community.O objetivo deste trabalho foi avaliar o efeito de duas cepas de Bacillus thuringiensis var. kurstaki sobre microrganismos na rizosfera do sorgo. As cepas foram a HD1, produtora do cristal bioinseticida, e a 407, uma mutante não-produtora. As duas cepas não influenciam a comunidade microbiana, mas reduzem o crescimento da planta. A colonização micorrízica e a população de fixadores de N2 de vida livre aumentaram.

  17. Regularized Statistical Analysis of Anatomy

    DEFF Research Database (Denmark)

    Sjöstrand, Karl

    2007-01-01

    This thesis presents the application and development of regularized methods for the statistical analysis of anatomical structures. Focus is on structure-function relationships in the human brain, such as the connection between early onset of Alzheimer’s disease and shape changes of the corpus cal...

  18. Regular expressions cookbook

    CERN Document Server

    Goyvaerts, Jan

    2009-01-01

    This cookbook provides more than 100 recipes to help you crunch data and manipulate text with regular expressions. Every programmer can find uses for regular expressions, but their power doesn't come worry-free. Even seasoned users often suffer from poor performance, false positives, false negatives, or perplexing bugs. Regular Expressions Cookbook offers step-by-step instructions for some of the most common tasks involving this tool, with recipes for C#, Java, JavaScript, Perl, PHP, Python, Ruby, and VB.NET. With this book, you will: Understand the basics of regular expressions through a

  19. Regular expression containment

    DEFF Research Database (Denmark)

    Henglein, Fritz; Nielsen, Lasse

    2011-01-01

    * for Kleene-star, and a general coin- duction rule as the only additional rule. Our axiomatization gives rise to a natural computational inter- pretation of regular expressions as simple types that represent parse trees, and of containment proofs as coercions. This gives the axiom- atization a Curry...... to be undecidable. We discuss application of regular expressions as types to bit coding of strings and hint at other applications to the wide-spread use of regular expressions for substring matching, where classical automata-theoretic techniques are a priori inapplicable. Neither regular expressions as types nor...

  20. Regularization by External Variables

    DEFF Research Database (Denmark)

    Bossolini, Elena; Edwards, R.; Glendinning, P. A.

    2016-01-01

    Regularization was a big topic at the 2016 CRM Intensive Research Program on Advances in Nonsmooth Dynamics. There are many open questions concerning well known kinds of regularization (e.g., by smoothing or hysteresis). Here, we propose a framework for an alternative and important kind of regula...... of regularization, by external variables that shadow either the state or the switch of the original system. The shadow systems are derived from and inspired by various applications in electronic control, predator-prey preference, time delay, and genetic regulation....

  1. Regularity effect in prospective memory during aging

    Directory of Open Access Journals (Sweden)

    Geoffrey Blondelle

    2016-10-01

    Full Text Available Background: Regularity effect can affect performance in prospective memory (PM, but little is known on the cognitive processes linked to this effect. Moreover, its impacts with regard to aging remain unknown. To our knowledge, this study is the first to examine regularity effect in PM in a lifespan perspective, with a sample of young, intermediate, and older adults. Objective and design: Our study examined the regularity effect in PM in three groups of participants: 28 young adults (18–30, 16 intermediate adults (40–55, and 25 older adults (65–80. The task, adapted from the Virtual Week, was designed to manipulate the regularity of the various activities of daily life that were to be recalled (regular repeated activities vs. irregular non-repeated activities. We examine the role of several cognitive functions including certain dimensions of executive functions (planning, inhibition, shifting, and binding, short-term memory, and retrospective episodic memory to identify those involved in PM, according to regularity and age. Results: A mixed-design ANOVA showed a main effect of task regularity and an interaction between age and regularity: an age-related difference in PM performances was found for irregular activities (older < young, but not for regular activities. All participants recalled more regular activities than irregular ones with no age effect. It appeared that recalling of regular activities only involved planning for both intermediate and older adults, while recalling of irregular ones were linked to planning, inhibition, short-term memory, binding, and retrospective episodic memory. Conclusion: Taken together, our data suggest that planning capacities seem to play a major role in remembering to perform intended actions with advancing age. Furthermore, the age-PM-paradox may be attenuated when the experimental design is adapted by implementing a familiar context through the use of activities of daily living. The clinical

  2. [The influence of physical loads on the functional parameters of the eyes in the children and adolescents regularly engaged in sports activities].

    Science.gov (United States)

    Yurova, O V; Andjelova, D V; Chayka, A A

    2017-01-01

    Myopia (short-sightedness) is the most common refractive disorder throughout the world prone to progression which is caused, inter alia, by violation of the working regime and resting conditions in the combination with the enhanced physical and psychological stresses. The objective of the present study was to evaluate the influence of the strenuous physical exercises on the visual analyzer in the children and adolescents regularly engaged in sports activities. A total of 600 children and adolescents at the age from 8 to 17 years were recruited for the participation in the study. They were allocated to two groups of 300 subjects each. The first group was comprised of the children regularly involved in sport activities ('athletes') while the second group included the children and adolescents not involved in the sports activities on a regular basis ('schoolchildren'). The groups were additionally divided into two subgroups that consisted of 150 members each. One subgroup within each group was composed of the persons with emmetropic refraction ('healthy') while the other included the children presenting with mild or moderately severe myopia. The parameters of visual acuity, the length of the anterior-posterior segment of the eye, and indices of regional hemodynamics of the eye were evaluated in all the participants of the study. Twelve months after the initiation of the study, the members of the first group ('athletes') were found to exhibit a slight decrease in visual acuity with and without ts correction and without correction as well as a statistically significant decrease of refraction by 0.14±0.18 dptr on the average (p=0.009). In the members of the second group not engaged in sports activities on a regular bases ('schoolchildren#), the decrease in visual acuity without correction and parameters of refraction averaged 0.06±0.19 dptr (p=0.004) and 0.35±0.61 dptr (presults of the present study give evidence that physical training on a regular basis facilitates

  3. Efeitos de três modalidades de atividade física na capacidade funcional de idosos Efectos de tres modalidades de actividad física en la capacidad funcional de adultos mayores Effects of three methods of physical activity in functional ability of elderly

    Directory of Open Access Journals (Sweden)

    Deisy Terumi Ueno

    2012-06-01

    Full Text Available O objetivo do presente estudo foi analisar e comparar os efeitos de três modalidades de atividade física: atividade física geral, dança e musculação, na capacidade funcional de idosos. A amostra foi composta por 94 idosos com idade média de 64,06 ± 7,38 anos, que participavam do PROFIT. Para a avaliação foi utilizada a bateria de testes da AAHPERD, da qual se obtém os níveis de flexibilidade, coordenação, agilidade e equilíbrio dinâmico, resistência de força e resistência aeróbia geral, antes e após quatro meses de intervenção. Os resultados apontaram de uma maneira geral uma manutenção nos níveis dos componentes da capacidade funcional. Os participantes do grupo atividade física geral obtiveram melhora dos resultados nos componentes: resistência de força, agilidade e equilíbrio dinâmico. Pode-se concluir que a prática de atividade física regular e sistematizada, independentemente da modalidade, pode ter influência positiva no desempenho funcional de idosos, podendo preservar sua independência e autonomia.El objetivo de este estudio fue analizar y comparar los efectos de actividad física generalizada, danza y musculación en la capacidad funcional de adultos mayores. La muestra consistió en 94 adultos mayores con promedio de edad de 64,06 ± 7,38 años, participantes en el PROFIT. Para la evaluación se utilizó de la batería de testes de la AAHPERD, la cual se puede obtener los niveles de flexibilidad, coordinación, agilidad y equilibrio dinámico, resistencia de fuerza y resistencia general, antes y después de cuatro meses de intervención. Los resultados mostraron una manutención en los niveles de los componentes funcionales. Lo grupo de actividad física general tuvieron mejores resultados en la resistencia de fuerza, agilidad y equilibrio dinámico. Se conclui que la práctica de actividad física regular y sistematizada, independiente dela modalidad, puede tener una influencia positiva en el desempe

  4. Maximum mutual information regularized classification

    KAUST Repository

    Wang, Jim Jing-Yan

    2014-09-07

    In this paper, a novel pattern classification approach is proposed by regularizing the classifier learning to maximize mutual information between the classification response and the true class label. We argue that, with the learned classifier, the uncertainty of the true class label of a data sample should be reduced by knowing its classification response as much as possible. The reduced uncertainty is measured by the mutual information between the classification response and the true class label. To this end, when learning a linear classifier, we propose to maximize the mutual information between classification responses and true class labels of training samples, besides minimizing the classification error and reducing the classifier complexity. An objective function is constructed by modeling mutual information with entropy estimation, and it is optimized by a gradient descend method in an iterative algorithm. Experiments on two real world pattern classification problems show the significant improvements achieved by maximum mutual information regularization.

  5. Regular Simple Queues of Protein Contact Maps.

    Science.gov (United States)

    Guo, Qiang-Hui; Sun, Lisa Hui; Wang, Jian

    2017-01-01

    A protein fold can be viewed as a self-avoiding walk in certain lattice model, and its contact map is a graph that represents the patterns of contacts in the fold. Goldman, Istrail, and Papadimitriou showed that a contact map in the 2D square lattice can be decomposed into at most two stacks and one queue. In the terminology of combinatorics, stacks and queues are noncrossing and nonnesting partitions, respectively. In this paper, we are concerned with 2-regular and 3-regular simple queues, for which the degree of each vertex is at most one and the arc lengths are at least 2 and 3, respectively. We show that 2-regular simple queues are in one-to-one correspondence with hill-free Motzkin paths, which have been enumerated by Barcucci, Pergola, Pinzani, and Rinaldi by using the Enumerating Combinatorial Objects method. We derive a recurrence relation for the generating function of Motzkin paths with [Formula: see text] peaks at level i, which reduces to the generating function for hill-free Motzkin paths. Moreover, we show that 3-regular simple queues are in one-to-one correspondence with Motzkin paths avoiding certain patterns. Then we obtain a formula for the generating function of 3-regular simple queues. Asymptotic formulas for 2-regular and 3-regular simple queues are derived based on the generating functions.

  6. Annotation of Regular Polysemy

    DEFF Research Database (Denmark)

    Martinez Alonso, Hector

    Regular polysemy has received a lot of attention from the theory of lexical semantics and from computational linguistics. However, there is no consensus on how to represent the sense of underspecified examples at the token level, namely when annotating or disambiguating senses of metonymic words...

  7. Accelerating regular polygon beams.

    Science.gov (United States)

    Barwick, Shane

    2010-12-15

    Beams that possess high-intensity peaks that follow curved paths of propagation under linear diffraction have recently been shown to have a multitude of interesting uses. In this Letter, a family of phase-only masks is derived, and each mask gives rise to multiple accelerating intensity maxima. The curved paths of the peaks can be described by the vertices of a regular polygon that is centered on the optic axis and expands with propagation.

  8. Una ecuación diferencial para el cálculo de las funciones de Jost para potenciales regulares Aplicación al sistema e‾+ H(1s A differential equation for the calculation of the functions de jost for regular potentials Application to the system e

    Directory of Open Access Journals (Sweden)

    Héctor Maya Taboada

    2011-06-01

    Full Text Available La función de Jost Fl es el concepto teórico que permite estudiar de una manera unificada los estados ligados, virtuales, dispersados y resonantes que pueden originarse en las interacciones entre dos sistemas cuánticos. En teoría de colisiones la función de Jost Fl juega un papel muy importante, puesto que se relaciona de forma directa con la matriz de dispersión S. En la mayoría de los métodos existentes en teoría de colisiones para el cálculo de la función Fl, primero es necesario conocer la solución regular del sistema tratado, la cual se obtiene via solución de la ecuación radial de Schrödinger, para poder hallar después la función Fl. Con la metodología propuesta en este trabajo se obtieneuna ecuación diferencial lineal ordinaria de segundo orden cuya solución en los límites asintóticos coincide con la función Fl. La ventaja del trabajo presente es que al solucionar la ecuación diferencial, mencionada antes, se puedeobtener de manera directa la función Fl, sin tener que hallar la solución regular del problema. Otra ventaja es que no importando las condiciones iniciales (reales que se escojan para la solución de la ecuación diferencial, siempre se obtienen los mismos elementos de la matriz S. Como un ejemplo y prueba de la metodología, se resuelve dicha ecuación diferencial numéricamente, para la dispersión elástica de electrones por átomos de hidrogeno en el estado base a bajas energías (e− + H(1s, obteniendo para este sistema la función Fl, los elementos de la matriz S y los corrimientos de fase, estos últimos se comparan con los calculados por Klaus BartschatThe function of Jost Fl is the theoretical concept that allows to study in an unified way the bound, virtual, scattered and resonant states that can originate in the interactions between two quantum systems. In theory of collisions the function of Jost Fl plays a very important role, since it is related in a direct way with the scattering

  9. Regular Single Valued Neutrosophic Hypergraphs

    Directory of Open Access Journals (Sweden)

    Muhammad Aslam Malik

    2016-12-01

    Full Text Available In this paper, we define the regular and totally regular single valued neutrosophic hypergraphs, and discuss the order and size along with properties of regular and totally regular single valued neutrosophic hypergraphs. We also extend work on completeness of single valued neutrosophic hypergraphs.

  10. The geometry of continuum regularization

    Energy Technology Data Exchange (ETDEWEB)

    Halpern, M.B.

    1987-03-01

    This lecture is primarily an introduction to coordinate-invariant regularization, a recent advance in the continuum regularization program. In this context, the program is seen as fundamentally geometric, with all regularization contained in regularized DeWitt superstructures on field deformations.

  11. Regularization of B-Spline Objects.

    Science.gov (United States)

    Xu, Guoliang; Bajaj, Chandrajit

    2011-01-01

    By a d-dimensional B-spline object (denoted as ), we mean a B-spline curve (d = 1), a B-spline surface (d = 2) or a B-spline volume (d = 3). By regularization of a B-spline object we mean the process of relocating the control points of such that they approximate an isometric map of its definition domain in certain directions and is shape preserving. In this paper we develop an efficient regularization method for , d = 1, 2, 3 based on solving weak form L(2)-gradient flows constructed from the minimization of certain regularizing energy functionals. These flows are integrated via the finite element method using B-spline basis functions. Our experimental results demonstrate that our new regularization method is very effective.

  12. Effect of hyperbaric oxygen therapy on liver function during intermittent ischemia Efeito da oxigenoterapia hiperbárica sobre a função hepática na isquemia intermitente

    Directory of Open Access Journals (Sweden)

    Leticia Botigeli Baldim

    2013-01-01

    Full Text Available PURPOSE: To analyze the effects of hyperbaric oxygen therapy on liver function in rats previously subjected to ischemia and reperfusion. METHODS: A randomly distribution of 23 Wistar rats was conducted into three groups: SHAM, animals subjected to surgical stress without restricting blood flow by clamping the hepatic pedicle, IR, rats underwent hepatic vascular occlusion intermittently for two complete cycles of 15 minutes of ischemia followed by 5 min of reperfusion, IR / HBO, rats underwent hepatic pedicle clamping and thereafter exposed to hyperbaric oxygen pressure of 2 absolute atmospheres for 60 minutes. We evaluated liver function through mitochondrial function, determined by the stages 3 and 4 of respiration, respiratory control ratio (RCR and mitochondrial permeability transition (Swelling. Serum alanine aminotransferase (ALT and aspartate aminotransferase (AST were also quantified . We analyzed the results using the Mann-Whitney test and were considered significant all results with p OBJETIVO: Analisar os efeitos da oxigenoterapia hiperbárica sobre a função hepática de ratos previamente submetidos à isquemia e reperfusão. MÉTODOS: Realizou-se a distribuição aleatória de 23 ratos Wistar em três grupos: SHAM, animais submetidos ao estresse cirúrgico sem restrição de fluxo sanguíneo por clampeamento do pedículo hepático; IR ratos submetidos a oclusão vascular hepática de maneira intermitente em dois ciclos completos de 15 minutos de isquemia, seguidos por 5 min de reperfusão; IR/HBO, ratos submetidos ao clampeamento do pedículo hepático e ,ulteriormente , expostos a oxigenoterapia hiperbárica a pressão de 2 atmosferas absolutas durante 60 minutos. Avaliou-se a função hepática através da função mitocondrial, determinada pelos estados 3 e 4 da respiração mitocondrial, razão de controle respiratório(RCR e transição de permeabilidade mitocondrial (Swelling .Quantificou-se também alanina aminotransferase e

  13. Determining the Effect of Early Feeding after Cesarean section Compared with Regular Diet on the Gastrointestinal Function of Women Referred to Tajrish Hospital, Iran

    Directory of Open Access Journals (Sweden)

    M Amiri-Siavoshani

    2016-10-01

    Full Text Available Background & aim: Early feeding after cesarean section can have beneficial effects, however, no sufficient study has been conducted in this area. The aim of this study was to determine the effects of early feeding on the gastrointestinal complications in women after cesarean section and comparing it with a regular diet.   Methods: The present randomized-clinical-trial study was conducted on 160 women who admitted to Shohada hospital and underwent cesarean section in 2011-2012. The inclusion criteria included women with gestational age more than 37 weeks, singleton pregnancy, having at least 8 hours of fasting, and regional anesthesia (spinal cord, respectively. After registration of demographic characteristics and pregnancy, women were randomly divided into two groups: Early feeding (2 hours after completion of the operation, 250 ml filtered juice, tea and biscuits style regime in the next 2 hours and 2 hours after the usual diet and the usual power (8 hours of operation clear liquid diet the day after the usual diet groups. Presence of gastrointestinal symptoms in 2, 4, 8 and 12 hours after surgery, time to the bowel sounds auscultation, passage of flatus and stool were recorded. Data were analyzed by SPSS software version13.The significance level of p-value was considered 0.05.   Conclusion: Early feeding caused the acceleration of gastrointestinal symptoms, earlier bowel sounds auscultation and earlier utilization of gas. It is recommended to investigate the different diets and examined the level of compliance and satisfaction.  

  14. Modular Regularization Algorithms

    DEFF Research Database (Denmark)

    Jacobsen, Michael

    2004-01-01

    an iterative method. The parameter choice method is also used to demonstrate the implementation of the standard-form transformation. We have implemented a simple preconditioner aimed at the preconditioning of the general-form Tikhonov problem and demonstrate its simplicity and effciency. The steps taken...... and used to set up the illposed problems in the toolbox. Hereby, we are able to write regularization algorithms that automatically exploit structure in the ill-posed problem without being rewritten explicitly. We explain how to implement a stopping criteria for a parameter choice method based upon...

  15. Os efeitos da estimulação elétrica funcional na assimetria cortical inter-hemisférica The effects of functional electrical stimulation on cortical interhemispheric asymmetry

    Directory of Open Access Journals (Sweden)

    Letícia Ecard

    2007-09-01

    Full Text Available O objetivo do presente estudo foi avaliar os efeitos da estimulação elétrica funcional na assimetria cortical inter-hemisférica. Para tal, simultaneamente ao registro da atividade eletroencefalográfica, realizou-se eletroestimulação no antebraço direito para estimulação da extensão do indicador. A amostra consistiu de 45 sujeitos randomizados em 3 grupos de 15 sujeitos cada: grupo controle (submetido a 24 blocos de estimulação com intensidade de corrente zero, grupo 1 (24 blocos e grupo 2 (36 blocos. A assimetria entre os pares de eletrodos F3-F4, C3-C4 e P3-P4 foi analisada ao longo dos grupos através de uma Anova. Os resultados apontaram para uma interação grupo x eletrodo e uma tendência de diminuição da assimetria inter-hemisférica após a eletroestimulação.The aim of the present study was to assess the effects of functional electrical stimulation (FES on cortical interhemispheric asymmetry. Electrostimulation was performed on the right forearm to stimulate the extension of the index finger. EEG activity was recorded simultaneously. The sample included 45 subjects randomly divided into 3 groups of 15 subjects each: control group (submitted to 24 blocks of stimulation at a null intensity current, group 1 (24 blocks and group 2 (36 blocks. Interhemispheric asymmetry between F3-F4, C3-C4 and P3-P4 was analyzed through an Anova. Results pointed out to a group x electrode interaction and a general tendency of asymmetry decrease after stimulation.

  16. Multiple graph regularized protein domain ranking

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    Wang Jim

    2012-11-01

    Full Text Available Abstract Background Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph model and parameters, and this remains a difficult problem for most of the protein domain ranking methods. Results To tackle this problem, we have developed the Multiple Graph regularized Ranking algorithm, MultiG-Rank. Instead of using a single graph to regularize the ranking scores, MultiG-Rank approximates the intrinsic manifold of protein domain distribution by combining multiple initial graphs for the regularization. Graph weights are learned with ranking scores jointly and automatically, by alternately minimizing an objective function in an iterative algorithm. Experimental results on a subset of the ASTRAL SCOP protein domain database demonstrate that MultiG-Rank achieves a better ranking performance than single graph regularized ranking methods and pairwise similarity based ranking methods. Conclusion The problem of graph model and parameter selection in graph regularized protein domain ranking can be solved effectively by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graphs to solving protein domain ranking applications.

  17. Multiple graph regularized protein domain ranking

    KAUST Repository

    Wang, Jim Jing-Yan

    2012-11-19

    Background: Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph model and parameters, and this remains a difficult problem for most of the protein domain ranking methods.Results: To tackle this problem, we have developed the Multiple Graph regularized Ranking algorithm, MultiG-Rank. Instead of using a single graph to regularize the ranking scores, MultiG-Rank approximates the intrinsic manifold of protein domain distribution by combining multiple initial graphs for the regularization. Graph weights are learned with ranking scores jointly and automatically, by alternately minimizing an objective function in an iterative algorithm. Experimental results on a subset of the ASTRAL SCOP protein domain database demonstrate that MultiG-Rank achieves a better ranking performance than single graph regularized ranking methods and pairwise similarity based ranking methods.Conclusion: The problem of graph model and parameter selection in graph regularized protein domain ranking can be solved effectively by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graphs to solving protein domain ranking applications. 2012 Wang et al; licensee BioMed Central Ltd.

  18. Morpho-functional study of ionizing radiation effects on the rabbits` femoral vein; Avaliacao morfofuncional do efeito da radiacao ionizante sobre a veia femoral. Estudo experimental em coelhos

    Energy Technology Data Exchange (ETDEWEB)

    Sakiyama, Mauro Yoshimitsu

    1995-12-31

    In this study we evaluate the effects of the ionizing radiation on the rabbits femoral vein. The samples of femoral vein were obtained from 56 New Zealand rabbits, male with ageing from 90 to 120 days, that were divided into 4 groups of 14 animals: one control group non-irradiated and three animal groups sacrificed 2 days, 14 days and 90 days after irradiation. In the three irradiated rabbits groups, each animal received the total dose 4000 cGy (rads) divided in 10 sessions of 400 cGy, a dose equivalent that utilized on clinical therapeutic. A morpho functional study of vein samples was carried out with: light microscopy: stained by hematoxin - eosin, Masson`s tricromic, and Verhoeff. Immunohistochemical: reactions of immunoperoxidase with monoclonal mouse anti-human endothelial cell factor CD-31 and anti-human Von Willebrand factor (factor VIII), to study the vein endothelium. Histomorphometry of elastic fiber system stained by Weigert`s resorcin-fuchsin with and without prior oxidation with oxone; for the study of mature, elaunin or pre-mature and oxytalan or young elastic fibers. Electronic microscopy: transmission and scanning. With the methodology utilized we observe changes in the femoral vein of the animals submitted to irradiation in relation to the control group, thus described: there is formation of vacuoles between the endothelium and the basal membrane, called sub endothelial vacuoles, in focal areas. The factor VIII and CD-31 endothelial antigens are preserved with no changes in their functions. Focal alterations are present in the endothelial surface with disorder in the setting and orientation of the endothelial cells. there is degeneration of the elastic fibers with significant decrease in their quantity in the stage, 2 days and 14 days after irradiation. There is increase in the quantity of elastic fibers in the late stage, 90 days after irradiation, tending to normality. In this present study, the changes described are not accompanied by venous

  19. Regularity of optimal transport maps and applications

    CERN Document Server

    Philippis, Guido

    2013-01-01

    In this thesis, we study the regularity of optimal transport maps and its applications to the semi-geostrophic system. The first two chapters survey the known theory, in particular there is a self-contained proof of Brenier’ theorem on existence of optimal transport maps and of Caffarelli’s Theorem on Holder continuity of optimal maps. In the third and fourth chapter we start investigating Sobolev regularity of optimal transport maps, while in Chapter 5 we show how the above mentioned results allows to prove the existence of Eulerian solution to the semi-geostrophic equation. In Chapter 6 we prove partial regularity of optimal maps with respect to a generic cost functions (it is well known that in this case global regularity can not be expected). More precisely we show that if the target and source measure have smooth densities the optimal map is always smooth outside a closed set of measure zero.

  20. Iterative regularization method in generalized inverse beamforming

    Science.gov (United States)

    Zhang, Zhifei; Chen, Si; Xu, Zhongming; He, Yansong; Li, Shu

    2017-05-01

    Beamforming based on microphone array is a method to identify sound sources. It can visualize the sound field of the source plane and reveal interesting acoustic information. Generalized inverse beamforming (GIB) is one important branch of beamforming techniques due to its high identification accuracy and computational efficiency. However, in real testing situation, errors caused by measurement noise and configuration problems may seriously reduce the beamforming accuracy. As an inverse problem, the stability of GIB can be improved with regularization methods. We proposed a new iterative regularization method for GIB by iteratively redefining the form of regularization matrix and calculating the corresponding solution. Moreover, the new method is applied to functional beamforming and double-layer antenna beamforming respectively. Numerical simulations and experiments are implemented. The results show that the proposed regularization method leads to more robust beamforming output and higher accuracy in both the two applications.

  1. Efeitos da estimulação elétrica funcional nos músculos do punho e dedos em indivíduos hemiparéticos: uma revisão sistemática da literatura Effects of functional electrical stimulation applied to the wrist and finger muscles of hemiparetic subjects: a systematic review of the literature

    Directory of Open Access Journals (Sweden)

    NF Arantes

    2007-12-01

    Full Text Available CONTEXTUALIZAÇÃO: Faz-se necessária sistematização das evidências disponíveis sobre os efeitos da estimulação elétrica em pacientes hemiplégicos após o acidente vascular cerebral. OBJETIVO: Realizar uma revisão sistemática da literatura referente aos efeitos da eletroestimulação funcional para os músculos do punho e dedos de pacientes hemiplégicos adultos. MÉTODOS: Uma busca foi realizada nas bases de dados Medline, Lilacs e PEDro, no período de fevereiro a março de 2006, por trabalhos que documentassem os efeitos da intervenção nas características neuromusculares, musculoesqueléticas e funcionais. Dados foram extraídos de forma padronizada de cada estudo, e a qualidade metodológica foi avaliada utilizando-se a escala PEDro. RESULTADOS: Oito estudos aleatorizados foram revisados. Em relação à avaliação da qualidade da evidência dos trabalhos, as pontuações variaram entre 3/10 e 7/10 na escala PEDro. Apesar da diversidade de protocolos, características de participantes e instrumentos utilizados terem impedido o agrupamento dos resultados, a síntese em níveis de evidência demonstrou que há forte evidência de efeitos positivos da eletroestimulação na força muscular, tônus, função motora e uso do membro na rotina diária. Há evidência moderada para efeitos na destreza e evidência limitada para efeitos na coordenação motora e independência em atividades de autocuidado. Não há evidências para ganhos na amplitude de extensão ativa de punho. CONCLUSÃO: Apesar de apresentarem limitações metodológicas, estudos aleatorizados relatam efeitos positivos do uso da eletroestimulação no punho e dedos, o que sugere que essa terapia seja eficaz para a promoção de função do membro superior afetado de indivíduos hemiplégicos.BACKGROUND: a systematization of the available evidence regarding the effects of electrical stimulation for hemiplegic patients following stroke is needed. OBJECTIVE: to

  2. Efeitos do uso de órtese na mobilidade funcional de crianças com paralisia cerebral The effects of the use of orthoses on the functional mobility of children with cerebral palsy

    Directory of Open Access Journals (Sweden)

    VCR Cury

    2006-01-01

    Full Text Available Objetivo:Comparar o desempenho motor de crianças com paralisia cerebral (PC em duas condições: com órtese e sem órtese. Métodos:Vinte crianças PC foram avaliadas utilizando-se o teste Gross Motor Function Measure (GMFM, a versão modificada da avaliação da marcha Physicians Rating Scale (PRS e entrevista com os pais para avaliar o uso de órteses na rotina diária. Resultados:O teste ANOVA que foi utilizado para avaliar o efeito do uso órtese na mobilidade das crianças revelou médias significantemente superiores na condição com órtese durante o desempenho motor grosso e na marcha. Entrevistas informaram que o uso de órteses estava inserido na rotina diária e os pais demonstraram percepção positiva com relação ao uso desse dispositivo. Conclusão: As órteses promoveram o desempenho de tarefas motoras da rotina diária de crianças com PC, podendo orientar os processos de avaliação e de intervenção dos profissionais que trabalham com essa clientela.Objective:To compare the motor performance of children with cerebral palsy (CP under two conditions: with and without orthoses. Method:Twenty children with CP were evaluated using the Gross Motor Function Measure test (GMFM, a modified version of the Physicians Rating Scale (PRS locomotion assessment, and an interview with their parents to evaluate the use of orthoses in their daily routine. Results:The ANOVA test was used to evaluate the effect of orthosis use on the children's mobility, and it revealed that, when orthosis was used, the means for gross motor function and gait assessments were significantly higher. The interviews confirmed that the use of orthoses was included in the daily routine, and the parents demonstrated positive perceptions regarding the use of such devices. Conclusion: Orthoses improved the performance of routine daily motor tasks among the children with CP, and this finding may serve to guide the assessment and intervention processes of professionals

  3. Efeito da inserção de implante anticoncepcional contendo acetato de nomegestrol sobre a função ovariana, muco cervical e penetração espermática Effects of a contraceptive implant containing nomegestrol acetate on ovarian function, cervical mucus and sperm penetration

    Directory of Open Access Journals (Sweden)

    Ione Cristina Barbosa

    2004-07-01

    Full Text Available OBJETIVOS: estudar o efeito de um único implante de acetato de nomegestrol (Uniplant sobre função ovariana, produção do muco cervical e penetração espermática, quando inserido na fase pré-ovulatória. MÉTODOS: estudo clínico aberto, comparativo, incluindo 20 mulheres com ciclos menstruais regulares que foram estudadas durante um ciclo menstrual antes (controle e um ciclo menstrual depois da inserção do implante. Dosagens de hormônio luteinizante (LH, estradiol e progesterona, ultra-sonografia vaginal, coleta de muco cervical e teste de penetração espermática foram realizados. Para comparação estatística, foi utilizado o Student t-test para grupos pareados e o teste Wilcoxon não paramétrico. Os valores estão mostrados como médias ± erro padrão. RESULTADOS: todos os ciclos controles foram ovulatórios com parâmetros normais. Os níveis pré-ovulatórios de estradiol e LH diminuíram significativamente de 603,2 ± 78,0 pmol/l e 22,5 ± 6,5 UI/l na pré-inserção do implante para 380,7 ± 51,9 pmol/l e 4,9 ± 1,3 UI/l 48 horas após a inserção (p OBJECTIVE: to study the effect of a single contraceptive implant of nomegestrol acetate (Uniplant on the ovarian function, cervical mucus production and sperm penetration, when inserted in women in the preovulatory phase. METHODS: twenty women with regular menstrual cycles were included in an open comparative study. All participants were investigated during one menstrual cycle before (control and one menstrual cycle after implant insertion. Measurements of estradiol, LH, and progesterone, as well as transvaginal sonography, cervical mucus examination and sperm penetration test, were carried out. Statistical analysis was performed with the paired t-test and the non-parametric test of Wilcoxon. RESULTS: all control cycles were ovulatory and presented normal parameters. Preovulatory estradiol and LH peak decreased significantly from 603.2 ± 78.0 pmo/l and 22.5 ± 6.5 IU/l at pre

  4. Regularity of Dual Gabor Windows

    Directory of Open Access Journals (Sweden)

    Ole Christensen

    2013-01-01

    Full Text Available We present a construction of dual windows associated with Gabor frames with compactly supported windows. The size of the support of the dual windows is comparable to that of the given window. Under certain conditions, we prove that there exist dual windows with higher regularity than the canonical dual window. On the other hand, there are cases where no differentiable dual window exists, even in the overcomplete case. As a special case of our results, we show that there exists a common smooth dual window for an interesting class of Gabor frames. In particular, for any value of K∈ℕ, there is a smooth function h which simultaneously is a dual window for all B-spline generated Gabor frames {EmbTnBN(x/2}m,n∈ℕ for B-splines BN of order N=1,…,2K+1 with a fixed and sufficiently small value of b.

  5. The regular consumption of a polyphenol-rich apple does not influence endothelial function: a randomised double-blind trial in hypercholesterolemic adults.

    Science.gov (United States)

    Auclair, S; Chironi, G; Milenkovic, D; Hollman, P C H; Renard, C M G C; Mégnien, J-L; Gariepy, J; Paul, J-L; Simon, A; Scalbert, A

    2010-10-01

    Epidemiological studies suggest that apple consumption is associated with a reduction in cardiovascular disease risk. Apple polyphenols may contribute to explain these effects. Endothelial dysfunction has been associated with early stage of atherosclerosis and polyphenols from various dietary sources have been shown to reverse it. The aim of the present study was to investigate the effect of the consumption of a polyphenol-rich apple on endothelial function. In all, 30 hypercholesterolemic volunteers were included in a double-blind, randomized crossover trial. They successively consumed 40 g of two lyophilized apples, polyphenol-rich and polyphenol-poor, providing respectively 1.43 and 0.21 g polyphenols per day during two 4-week periods separated by a 4-week washout period. Brachial artery flow-mediated vasodilation (FMD) was assessed at the beginning and at the end of each intervention period. FMD did not differ between the polyphenol-rich and the polyphenol-poor apples, neither did the other cardiovascular disease risk factors (plasma lipids, homocysteine, antioxidant capacity). These data suggest that over a 4-week period, the consumption of a polyphenol-rich apple does not improve vascular function in hypercholesterolemic patients.

  6. A modalidade de assistência Centro-Dia Geriátrico: efeitos funcionais em seis meses de acompanhamento multiprofissional The Geriatric Day-Care assistance mode: functional effects in a six month multidisciplinary health care program

    Directory of Open Access Journals (Sweden)

    Sandra Elizabeth Franciulli

    2007-04-01

    Full Text Available O objetivo deste artigo é descrever os efeitos da assistência multiprofissional na capacidade funcional de idosos atendidos em Centro-Dia Geriátrico após seis meses de acompanhamento. O método usado foi o estudo clínico observacional de seguimento. Catorze pacientes com idade superior a 80 anos foram avaliados na admissão ao serviço e após seis meses de acompanhamento, segundo os seguintes instrumentos: atividades diárias pelo Brazilian OARS Multidimensional Functional Assessment Questionnaire; estado cognitivo por meio do Mini-Mental State Exam, equilíbrio funcional pela Berg Balance Scale e mobilidade pelo Timed Up and Go Test. Foi realizada análise descritiva simples e, para comparação entre os dois momentos de avaliação, os testes Wilcoxon e T-pareado, a=0,05. Observou-se diferença significativa entre a avaliação e a reavaliação com melhora no decorrer do tempo para a capacidade funcional global (p=0,019 e equilíbrio funcional pelas tarefas de transferências posturais (p=0,041. As demais variáveis mostraram manutenção de seus valores no seguimento. Conclusão: a assistência multiprofissional em Centro-Dia potencializou melhora ou manutenção da capacidade funcional dos participantes, revelando ser uma alternativa promissora de modalidade de serviço para a saúde do idoso.The objective is to describe the functional capacity of elderly patients who took part in a six-month follow-up program at a geriatric day care center. The methods used were a six-month observation clinical study. The following tools were used to assess fourteen elderly patients over 80 years old at admission at the day care and for six months thereafter: Brazilian OARS Multidimensional Functional Assessment Questionnaire (daily life activities, Mini-Mental State Exam (cognition, Berg Balance Scale (functional balance evaluation and Timed Up and Go Test (mobility. Data were analyzed using descriptive statistics and Wilcoxon and paired-samples T

  7. Efeito de um programa de treinamento funcional no equilíbrio postural de idosas da comunidade Effect of a functional training program on community-dwelling elderly women's postural balance

    Directory of Open Access Journals (Sweden)

    Lygia Paccini Lustosa

    2010-06-01

    Full Text Available Programas de treino funcional podem colaborar na redução de incapacidades, quedas, problemas emocionais e sociais em idosos. O objetivo do estudo foi verificar o efeito de um programa de oito semanas de exercícios funcionais em idosas da comunidade, avaliando o impacto nas atividades instrumentais de vida diária (AIVD e no equilíbrio unipodálico. Deste estudo quasi-experimental participaram sete idosas da comunidade (71±8,1 anos, sem distinção de raça e/ ou condição social, excluindo-se aquelas com alterações cognitivas, doenças agudizadas ou neurológicas, quadro álgico na coluna ou articulações, labirintite, distúrbios visuais não-compensados, fratura prévia no último ano e utilização de apoio para a marcha. Todas responderam ao questionário de Lawton e se submeteram ao teste de apoio unipodálico antes e depois do programa, administrado três vezes por semana. O programa consistia em exercícios de marcha em flexão plantar, dorsiflexão, permanência em alternância de apoio unipodálico, marcha lateral com flexão de quadril aumentada e marcha tandem. Os resultados indicam melhora (p=0,042 no nível funcional (índice de Lawton após o programa e uma tendência à melhora no equilíbrio unipodálico, embora não-significante (p>0,105. O programa de exercícios proposto produziu pois melhora no desempenho das AIVD e uma tendência à melhora do equilíbrio estático, sugerindo ser relevante para aprimorar a autonomia das idosas.Functional training programs may help reduce elderly disabilities, falls, and emotional and social problems. The aim of this study was to assess the impact of an eight-week functional exercise program on aged women's instrumental activities of daily living (IADL and one-foot stance balance. Irrespective of race and/or social condition, 7 community-dwelling elderly women (aged 71±8.1 were selected, being excluded those with cognitive impairment, acute or neurological diseases, spine or joint

  8. Funções psicofísicas para área percebida, inferida e relembrada: o efeito da idade Psychophysics functions for perceptive, inference, and memory area: the effect of age

    Directory of Open Access Journals (Sweden)

    Paula Mariza Zedu Alliprandini

    2000-01-01

    Full Text Available O objetivo deste trabalho foi verificar o efeito da idade no expoente da função-potência nas Condições experimentais Perceptiva, Memória e Inferência. Para cada Condição, as faixas etárias dos sujeitos variaram de 17 a 34 anos (I, 38 a 57 anos (II e 58 a 77 anos de idade (III. Os sujeitos estimaram áreas dos Estados do Brasil, utilizando o método psicofísico de estimação de magnitude. Os resultados obtidos pelas três Faixas etárias não diferiram para cada Condição experimental, com exceção da Condição Memória (24 horas. A análise entre as Condições experimentais e Faixas etárias evidenciou uma diferença da Condição Perceptiva em relação às demais, não havendo diferenças entre as Condições Memória e Inferência. Os dados apresentados sugerem que no processo de relembrar, não há perda da informação em função da idade.The purpose of the present work was to verify the effect of age on the exponent of power function in a Perceptive, Memory, and Inference experimental conditions. The age levels were: 17-34 years (I, 38-57 years (II and 58-77 years (III. The observers estimated areas of Brazilian States using the psychophysic method of magnitude estimates. No significant differences were obtained among age levels for each experimental condition, except in the 24 hours-memory condition. The analysis among experimental conditions and ages showed a significant difference of Perceptual Conditions in comparison with the others. No significant difference between the Inference and Memory Conditions was found. The results indicated no loss of information due to age.

  9. Efeito da hidrólise tríptica e do pH sobre as propriedades funcionais do plasma bovino The effect of the tryptic hydrolysis and the pH on the functional properties of bovine plasma

    Directory of Open Access Journals (Sweden)

    Cléia Batista Dias Ornellas

    2003-04-01

    Full Text Available Visando a utilização do plasma bovino como agente funcional de alimentos, foram estudadas, na faixa de pH de 3,0 a 8,0, a solubilidade, a hidrofobicidade e a sua habilidade de formar e estabilizar emulsões. Para tal, foram determinados a capacidade emulsionante (EC, o índice de atividade emulsionante (EAI e a estabilidade da emulsão (ES. O efeito da ação da tripsina sobre estas propriedades foi, também, verificado, tendo sido preparados cinco hidrolisados enzimáticos. Os resultados obtidos indicam que a hidrofobicidade e o EAI apresentaram um máximo em pH 3,0 e 7,0, respectivamente, enquanto que as outras propriedades praticamente não foram influenciadas pela variação de pH. A hidrólise tríptica provocou uma redução da solubilidade e da EC, não afetou o EAI e a ES, tendo contribuído para melhorar apenas a hidrofobicidade, em alguns tempos de reação.Aiming to use of the bovine plasma as functional agent of foods, we studied its solubility, hidrophobicity and ability to form and to stabilize emulsions, in the range of pH from 3.0 to 8.0. Emulsifying capacity (EC, the emulsifying activity index (EAI and the stability of the emulsion (ES were determinated. The effect of the trypsin on these properties was also studied and five enzymatic hydrolysates were prepared. The results showed that hydrophobicity and EAI presented a maximum value at pH 3.0 and 7.0, respectively, while the other properties practically were not influenced by the pH variation. The tryptic hydrolysis produced a reduction of the solubility and EC, it showed no effect on EAI and ES and improved only the hidrophobicity in some periods of reaction.

  10. Accreting fluids onto regular black holes via Hamiltonian approach

    Energy Technology Data Exchange (ETDEWEB)

    Jawad, Abdul [COMSATS Institute of Information Technology, Department of Mathematics, Lahore (Pakistan); Shahzad, M.U. [COMSATS Institute of Information Technology, Department of Mathematics, Lahore (Pakistan); University of Central Punjab, CAMS, UCP Business School, Lahore (Pakistan)

    2017-08-15

    We investigate the accretion of test fluids onto regular black holes such as Kehagias-Sfetsos black holes and regular black holes with Dagum distribution function. We analyze the accretion process when different test fluids are falling onto these regular black holes. The accreting fluid is being classified through the equation of state according to the features of regular black holes. The behavior of fluid flow and the existence of sonic points is being checked for these regular black holes. It is noted that the three-velocity depends on critical points and the equation of state parameter on phase space. (orig.)

  11. Potencial de macroalgas marinhas da costa portuguesa como alimento funcional: efeitos benéficos em Drosophila melanogaster = Potential of seaweeds from the portuguese coast as functional food: beneficial effects in Drosophila melanogaster

    OpenAIRE

    Ferreira, João Miguel Mendes

    2017-01-01

    Dissertação de Mestrado em Biotecnologia para as Ciências da Saúde As macroalgas marinhas são um dos melhores exemplos de organismos marinhos com grandes aplicações considerando a sua composição rica em compostos bioativos com efeitos benéficos para a saúde. Assim, elas têm sido defendidas como alimento funcional e a sua inclusão na dieta humana é uma realidade, principalmente em países do Este Asiático. Com especial atenção aos seus efeitos toxicológicos, incluindo as ações de proteção co...

  12. Long-Term Regular Eccentric Exercise Decreases Neuropathic Pain-like Behavior and Improves Motor Functional Recovery in an Axonotmesis Mouse Model: the Role of Insulin-like Growth Factor-1.

    Science.gov (United States)

    Martins, Daniel F; Martins, Thiago C; Batisti, Ana Paula; Dos Santos Leonel, Larissa; Bobinski, Franciane; Belmonte, Luiz A O; Mazzardo-Martins, Leidiane; Cargnin-Ferreira, Eduardo; Santos, Adair R S

    2017-12-18

    Although training programs with regular eccentric (ECC) exercise are more commonly used for improving muscular strength and mobility, ECC exercise effects upon functional recovery of the sciatic nerve has not yet been determined. After sciatic nerve crush, different mice groups were subjected to run on the treadmill for 30 min at a speed of 6, 10, or 14 m/min with - 16° slope, 5 days per week, over 8 weeks. During the training time, neuropathic pain-like behavior (mechanical and cold hyperalgesia) was assessed and functional recovery was determined with the grip strength test and the Sciatic Functional and Static indexes (SFI and SSI). After 9 weeks, triceps surae muscle weight and morphological alterations were assessed. Tumor necrosis factor alpha (TNF-α), interleukin-1β (IL-1β), interleukin-4 (IL-4), interleukin-1Ra (IL-1Ra), insulin-like growth factor-1 (IGF-1) levels, and markers pro- and anti-inflammatory and regeneration, respectively, were quantified in the muscle and sciatic nerve on day 14 post-crushing. Exercised groups presented less neuropathic pain-like behavior and better functional recovery than non-exercised groups. Biochemically, ECC exercise reduced TNF-α increase in the muscle. ECC exercise increased sciatic nerve IGF-1 levels in sciatic nerve crush-subjected animals. These findings provide new evidence indicating that treatment with ECC might be a potential approach for neuropathy induced by peripheral nerve injury.

  13. Função endotelial vascular em pacientes com fluxo coronário lento e os efeitos do nebivolol Vascular endothelial function in patients with coronary slow flow and the effects of nebivolol

    Directory of Open Access Journals (Sweden)

    Yilmaz Gunes

    2011-10-01

    Full Text Available FUNDAMENTO: A função endotelial braquial tem sido associada ao fluxo lento coronário (FLC. O aumento do fluxo sanguíneo para a artéria braquial faz com que o endotélio libere óxido nítrico (ON, com subsequente vasodilatação. Além de sua atividade com betabloqueador, o nebivolol provoca vasodilatação, aumentando a liberação endotelial de ON. OBJETIVO: Avaliar os efeitos do nebivolol na função endotelial vascular em pacientes com FLC. MÉTODOS: 46 pacientes com FLC e 23 indivíduos com artérias coronárias epicárdicas normais foram examinados com ecocardiografia transtorácica e ultrassonografia da artéria braquial. Os pacientes foram reavaliados dois meses após o tratamento com aspirina ou aspirina e nebivolol. RESULTADOS: Os pacientes com FLC apresentaram maior índice de massa corporal (26,5 ± 3,3 vs. 23,8 ± 2,8, p BACKGROUND: Brachial endothelial function has been associated with coronary slow flow (CSF. Increasing blood flow to brachial artery provokes endothelium to release nitric oxide (NO with subsequent vasodilatation. Besides its β1-blocker activity, nebivolol causes vasodilatation by increasing endothelial NO release. OBJECTIVE: To assess the effects of nebivolol on vascular endothelial function in patients with CSF. METHODS: Forty-six patients with CSF and 23 individuals with normal epicardial coronary arteries were examined with transthoracic echocardiography and brachial artery ultrasonography. The patients were reevaluated two months after treatment with aspirin or aspirin plus nebivolol. RESULTS: Patients with CSF had higher body mass index (26.5 ± 3.3 vs. 23.8 ± 2.8, p < 0.001, mitral inflow isovolumetric relaxation time (IVRT (114.9 ± 18.0 vs. 95.0 ± 22.0 msec, p < 0.001 and lower left ventricular ejection fraction (LVEF (63.5 ± 3.1% vs. 65.4 ± 2.2, p = 0.009, HDL-cholesterol (39.4 ± 8.5 vs. 45.8 ± 7.7 mg/dL, p = 0.003 and brachial flow-mediated dilatation (FMD (6.1 ± 3.9% vs. 17.6 ± 4.5%, p < 0

  14. Adaptive Regularization of Neural Classifiers

    DEFF Research Database (Denmark)

    Andersen, Lars Nonboe; Larsen, Jan; Hansen, Lars Kai

    1997-01-01

    We present a regularization scheme which iteratively adapts the regularization parameters by minimizing the validation error. It is suggested to use the adaptive regularization scheme in conjunction with optimal brain damage pruning to optimize the architecture and to avoid overfitting. Furthermore......, we propose an improved neural classification architecture eliminating an inherent redundancy in the widely used SoftMax classification network. Numerical results demonstrate the viability of the method...

  15. Existence of connected regular and nearly regular graphs

    OpenAIRE

    Ganesan, Ghurumuruhan

    2018-01-01

    For integers $k \\geq 2$ and $n \\geq k+1$, we prove the following: If $n\\cdot k$ is even, there is a connected $k$-regular graph on $n$ vertices. If $n\\cdot k$ is odd, there is a connected nearly $k$-regular graph on $n$ vertices.

  16. Efeito da hidrocinesioterapia sobre qualidade de vida, capacidade funcional e qualidade do sono em pacientes com fibromialgia Effect of hydrotherapy on quality of life, functional capacity and sleep quality in patients with fibromyalgia

    Directory of Open Access Journals (Sweden)

    Kyara Morgana Oliveira Moura Silva

    2012-12-01

    Full Text Available INTRODUÇÃO: A síndrome da fibromialgia acomete 8% da população com mais de 40 anos de idade. Dos pacientes com fibromialgia, 75% queixam-se de má qualidade do sono. OBJETIVO: Avaliar os efeitos da hidrocinesioterapia sobre a capacidade funcional e a qualidade de sono em pacientes com fibromialgia. MÉTODOS: As pacientes foram atendidas na policlínica da UNASP. Foram avaliadas 60 pacientes portadoras de fibromialgia na faixa etária entre 30 e 65 anos. Das pacientes avaliadas, 20 foram excluídas e 10 desistiram devido à impossibilidade de apresentar-se no horário do programa de exercícios. Todas as pacientes responderam aos seguintes questionários: Questionário sobre o Impacto daFibromialgia (QIF, Índice da Qualidade do Sono de Pittsburgh e Escala de Sonolência de Epworth. As sessões foram realizadas duas vezes por semana, com duração de 60 minutos cada, por um período de dois meses. RESULTADOS: A média da idade das pacientes foi de 45 anos; 66% eram trabalhadoras ativas e 34% estavam afastadas do trabalho. Verificouse que imediatamente após participarem do programa da hidrocinesioterapia, as pacientes apresentaram melhora nos seguintes aspectos avaliados por meio do QIF: capacidade funcional, absenteísmo ao trabalho, capacidade de serviço, intensidade da dor, fadiga, cansaço matinal, rigidez (P INTRODUCTION: Fibromyalgia affects 8% of the population over the age of 40 years, and 75% of the patients with fibromyalgia have poor sleep quality. OBJECTIVE: To assess the effects of hydrotherapy on the physical function and sleep quality of patients with fibromyalgia. METHODS: Patients were under clinical care at the UNASP Outpatient Clinic. This study assessed 60 female patients with fibromyalgia aged between 30 and 65 years. Out of the 60 patients assessed, 20 were excluded and 10 left the study because they could not comply with the time schedule. All patients completed the following questionnaires: Fibromyalgia Impact

  17. Implementing regularization implicitly via approximate eigenvector computation

    OpenAIRE

    Mahoney, Michael W.; Orecchia, Lorenzo

    2010-01-01

    Regularization is a powerful technique for extracting useful information from noisy data. Typically, it is implemented by adding some sort of norm constraint to an objective function and then exactly optimizing the modified objective function. This procedure often leads to optimization problems that are computationally more expensive than the original problem, a fact that is clearly problematic if one is interested in large-scale applications. On the other hand, a large body of empirical work...

  18. Fractional Regularization Term for Variational Image Registration

    Directory of Open Access Journals (Sweden)

    Rafael Verdú-Monedero

    2009-01-01

    Full Text Available Image registration is a widely used task of image analysis with applications in many fields. Its classical formulation and current improvements are given in the spatial domain. In this paper a regularization term based on fractional order derivatives is formulated. This term is defined and implemented in the frequency domain by translating the energy functional into the frequency domain and obtaining the Euler-Lagrange equations which minimize it. The new regularization term leads to a simple formulation and design, being applicable to higher dimensions by using the corresponding multidimensional Fourier transform. The proposed regularization term allows for a real gradual transition from a diffusion registration to a curvature registration which is best suited to some applications and it is not possible in the spatial domain. Results with 3D actual images show the validity of this approach.

  19. A criterion for regular sequences

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    D P PATIL1, U STORCH2 and J ST ¨UCKRAD3. 1Department of Mathematics, Indian Institute of Science, Bangalore 560 012, India ... For general notations in com- mutative algebra we also refer to [1]. ... Note that every sequence is a strongly regular as well as regular sequence on the zero module. Further, it is clear that a ...

  20. Natural selection and mechanistic regularity.

    Science.gov (United States)

    DesAutels, Lane

    2016-06-01

    In this article, I address the question of whether natural selection operates regularly enough to qualify as a mechanism of the sort characterized by Machamer, Darden, and Craver (2000). Contrary to an influential critique by Skipper and Millstein (2005), I argue that natural selection can be seen to be regular enough to qualify as an MDC mechanism just fine-as long as we pay careful attention to some important distinctions regarding mechanistic regularity and abstraction. Specifically, I suggest that when we distinguish between process vs. product regularity, mechanism-internal vs. mechanism-external sources of irregularity, and abstract vs. concrete regularity, we can see that natural selection is only irregular in senses that are unthreatening to its status as an MDC mechanism. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Bypassing the Limits of Ll Regularization: Convex Sparse Signal Processing Using Non-Convex Regularization

    Science.gov (United States)

    Parekh, Ankit

    Sparsity has become the basis of some important signal processing methods over the last ten years. Many signal processing problems (e.g., denoising, deconvolution, non-linear component analysis) can be expressed as inverse problems. Sparsity is invoked through the formulation of an inverse problem with suitably designed regularization terms. The regularization terms alone encode sparsity into the problem formulation. Often, the ℓ1 norm is used to induce sparsity, so much so that ℓ1 regularization is considered to be `modern least-squares'. The use of ℓ1 norm, as a sparsity-inducing regularizer, leads to a convex optimization problem, which has several benefits: the absence of extraneous local minima, well developed theory of globally convergent algorithms, even for large-scale problems. Convex regularization via the ℓ1 norm, however, tends to under-estimate the non-zero values of sparse signals. In order to estimate the non-zero values more accurately, non-convex regularization is often favored over convex regularization. However, non-convex regularization generally leads to non-convex optimization, which suffers from numerous issues: convergence may be guaranteed to only a stationary point, problem specific parameters may be difficult to set, and the solution is sensitive to the initialization of the algorithm. The first part of this thesis is aimed toward combining the benefits of non-convex regularization and convex optimization to estimate sparse signals more effectively. To this end, we propose to use parameterized non-convex regularizers with designated non-convexity and provide a range for the non-convex parameter so as to ensure that the objective function is strictly convex. By ensuring convexity of the objective function (sum of data-fidelity and non-convex regularizer), we can make use of a wide variety of convex optimization algorithms to obtain the unique global minimum reliably. The second part of this thesis proposes a non-linear signal

  2. Basic analysis of regularized series and products

    CERN Document Server

    Jorgenson, Jay A

    1993-01-01

    Analytic number theory and part of the spectral theory of operators (differential, pseudo-differential, elliptic, etc.) are being merged under amore general analytic theory of regularized products of certain sequences satisfying a few basic axioms. The most basic examples consist of the sequence of natural numbers, the sequence of zeros with positive imaginary part of the Riemann zeta function, and the sequence of eigenvalues, say of a positive Laplacian on a compact or certain cases of non-compact manifolds. The resulting theory is applicable to ergodic theory and dynamical systems; to the zeta and L-functions of number theory or representation theory and modular forms; to Selberg-like zeta functions; andto the theory of regularized determinants familiar in physics and other parts of mathematics. Aside from presenting a systematic account of widely scattered results, the theory also provides new results. One part of the theory deals with complex analytic properties, and another part deals with Fourier analys...

  3. Efeito da fisioterapia no desempenho funcional do membro superior no pós-operatório de câncer de mama = Physical therapy effects on upper functional performance after breast cancer surgery

    OpenAIRE

    Rett,Mariana Tirolli; Santos, Ana Karine Gois dos; Mendonça, Andreza Carvalho Rabelo; Oliveira, Iris Alves de; Santana, Josimari Melo de

    2013-01-01

    Objetivo: Verificar o efeito da fisioterapia na amplitude de movimento (ADM) e no desempenho funcional do membro superior homolateral no pós-operatório para tratamento do câncer de mama e correlacionar estas variáveis. Materiais e Métodos: Série de casos envolvendo mulheres submetidas à cirurgia unilateral para tratamento do câncer de mama, associado à linfadenectomia axilar. A ADM foi mensurada nos dois membros superiores através da goniometria, sendo o membro contralateral à cirurgia consid...

  4. Effects of strength and flexibility training on functional performance of healthy older people Efeitos do treinamento de força e flexibilidade no desempenho funcional de idosos saudáveis

    Directory of Open Access Journals (Sweden)

    Rafaella R. Locks

    2012-06-01

    Full Text Available OBJECTIVE: To evaluate the effects of stretching and/or resistive exercise, followed by detraining, on the functional status of older people. METHODS: Forty-five subjects were divided into four groups: control (CG; n=13; 66±6 years, stretching (SG; n=10; 69±6 years, resistive exercise (RG; n=13; 69±5 years, and resistive exercise and stretching (RSG; n=9; 66±5 years. The CG did not perform any exercise. The SG, RG, and RSG had warm-up sessions prior to performing lower-body exercises twice a week. The SG performed 4 repetitions of stretching. Resistive exercise was performed at a load of 65% of 10 repetitions maximum (RM for five weeks, 70% for the next four weeks, and 75% for the last three weeks of the program. The RSG performed both exercises. Cardiorespiratory capacity was evaluated using the 6-minute walk test (6MWT at baseline, at the six- and 12-week follow-ups, and after a six-week period of detraining. Lower limb muscle strength was assessed using the stand up from a chair and sit down test (SUCSD, and blood pressure was measured using a sphygmomanometer and a stethoscope. The results were analyzed using ANOVA (pOBJETIVO: Avaliar os efeitos do alongamento e/ou exercício resistido e destreinamento na performance funcional de idosos. MÉTODOS: Quarenta e cinco sujeitos foram divididos em 4 grupos: controle (CG; n=13; 66±6 anos, alongamento (SG; n=10; 69±6 anos, resistido (RG; n=13; 69±5 anos, e resistido e alongamento (RSG; n=9; 66±5 anos. O CG não realizou exercícios. Os grupos SG, RG e RSG realizaram aquecimento seguido de exercícios para membros inferiores 2 vezes por semana. O SG realizou 4 repetições de alongamento. O exercício resistido foi realizado com carga de 65% de 10 repetições máximas (RM durante 5 semanas, 70% nas 4 semanas seguintes e 75% nas últimas 3 semanas. O RSG realizou ambos os exercícios. Antes, após 6, 12 semanas, e após 6 semanas de destreinamento, a aptidão cardiorrespiratória foi avaliada

  5. Spherical Averages on Regular and Semiregular Graphs

    OpenAIRE

    Douma, Femke

    2008-01-01

    In 1966, P. Guenther proved the following result: Given a continuous function f on a compact surface M of constant curvature -1 and its periodic lift g to the universal covering, the hyperbolic plane, then the averages of the lift g over increasing spheres converge to the average of the function f over the surface M. In this article, we prove similar results for functions on the vertices and edges of regular and semiregular graphs, with special emphasis on the convergence rate. We also consid...

  6. Regularized Regression and Density Estimation based on Optimal Transport

    KAUST Repository

    Burger, M.

    2012-03-11

    The aim of this paper is to investigate a novel nonparametric approach for estimating and smoothing density functions as well as probability densities from discrete samples based on a variational regularization method with the Wasserstein metric as a data fidelity. The approach allows a unified treatment of discrete and continuous probability measures and is hence attractive for various tasks. In particular, the variational model for special regularization functionals yields a natural method for estimating densities and for preserving edges in the case of total variation regularization. In order to compute solutions of the variational problems, a regularized optimal transport problem needs to be solved, for which we discuss several formulations and provide a detailed analysis. Moreover, we compute special self-similar solutions for standard regularization functionals and we discuss several computational approaches and results. © 2012 The Author(s).

  7. NONCONVEX REGULARIZATION FOR SHAPE PRESERVATION

    Energy Technology Data Exchange (ETDEWEB)

    CHARTRAND, RICK [Los Alamos National Laboratory

    2007-01-16

    The authors show that using a nonconvex penalty term to regularize image reconstruction can substantially improve the preservation of object shapes. The commonly-used total-variation regularization, {integral}|{del}u|, penalizes the length of the object edges. They show that {integral}|{del}u|{sup p}, 0 < p < 1, only penalizes edges of dimension at least 2-p, and thus finite-length edges not at all. We give numerical examples showing the resulting improvement in shape preservation.

  8. Regularization with a pruning prior

    DEFF Research Database (Denmark)

    Goutte, Cyril; Hansen, Lars Kai

    1997-01-01

    We investigate the use of a regularization priorthat we show has pruning properties. Analyses areconducted both using a Bayesian framework and withthe generalization method, on a simple toyproblem. Results are thoroughly compared withthose obtained with a traditional weight decay.......We investigate the use of a regularization priorthat we show has pruning properties. Analyses areconducted both using a Bayesian framework and withthe generalization method, on a simple toyproblem. Results are thoroughly compared withthose obtained with a traditional weight decay....

  9. Commuting Π-regular rings

    Directory of Open Access Journals (Sweden)

    Shervin Sahebi

    2014-05-01

    Full Text Available ‎$R$ is called commuting regular ring (resp‎. ‎semigroupif‎ for each $x,y\\in R$ there exists $a\\in R$‎ such that$xy=yxayx$‎. ‎In this paper‎, ‎we introduce the concept of‎‎commuting $\\pi$-regular rings (resp‎. ‎semigroups and‎‎study various properties of them.

  10. Implicit Regularization in Deep Learning

    OpenAIRE

    Neyshabur, Behnam

    2017-01-01

    In an attempt to better understand generalization in deep learning, we study several possible explanations. We show that implicit regularization induced by the optimization method is playing a key role in generalization and success of deep learning models. Motivated by this view, we study how different complexity measures can ensure generalization and explain how optimization algorithms can implicitly regularize complexity measures. We empirically investigate the ability of these measures to ...

  11. (2 + 1)-dimensional regular black holes with nonlinear electrodynamics sources

    Science.gov (United States)

    He, Yun; Ma, Meng-Sen

    2017-11-01

    On the basis of two requirements: the avoidance of the curvature singularity and the Maxwell theory as the weak field limit of the nonlinear electrodynamics, we find two restricted conditions on the metric function of (2 + 1)-dimensional regular black hole in general relativity coupled with nonlinear electrodynamics sources. By the use of the two conditions, we obtain a general approach to construct (2 + 1)-dimensional regular black holes. In this manner, we construct four (2 + 1)-dimensional regular black holes as examples. We also study the thermodynamic properties of the regular black holes and verify the first law of black hole thermodynamics.

  12. Bifurcations in the regularized Ericksen bar model

    OpenAIRE

    Grinfeld, M.; Lord, G. J. (Gabriel J.)

    2007-01-01

    We consider the regularized Ericksen model of an elastic bar on an elastic foundation on an interval with Dirichlet boundary conditions as a two-parameter bifurcation problem. We explore, using local bifurcation analysis and continuation methods, the structure of bifurcations from double zero eigenvalues. Our results provide evidence in support of M\\"uller's conjecture \\cite{Muller} concerning the symmetry of local minimizers of the associated energy functional and describe in detail the stru...

  13. Effects of regular water- and land-based exercise on physical function after 5 years: A long-term study on the well-being of older Japanese adults.

    Science.gov (United States)

    Tsujimoto, Tomoya; Ikemoto, Tatsunori; Kurisuno, Makoto; Akao, Machiko; Miyagawa, Hirofumi; Inoue, Msayuki; Arai, Young-Chang P; Ushida, Takahiro; Deie, Masataka

    2017-11-01

    To investigate the effects of 5 years of physical exercise on functional parameters among older Japanese adults who carried out water- or land-based exercise. We retrospectively investigated data from 5707 medical examinations and enrolled 77 older adults into the study. Eligible participants had to be aged ≥60 years, and engaged in water-based exercise (n = 38) or a combination of water- and land-based exercise (n = 39) for at least 80% of their total exercise time for over 5 years at our fitness center. In statistical analysis, a two-way repeated-measures analysis of variance was carried out to examine the effects over time and by exercise type, and the changes in each parameter over 5 years were also compared between the two groups. We found significant main effects and an interaction between time and exercise type for gait speed, with an early decline in the combined exercise group, as well as significant main effects of time, showing a functional decline in grip strength, one-leg standing time and step/height ratio in both exercise types at the 5-year follow up. The 5-year changes in each parameter did not differ between the two groups despite the frequency of exercise, even though we found a negative correlation between changes in one-leg standing time and total amount of water-based exercise. Contrary to expectations, these results suggest that regular engagement in water-based exercise, even combined with land-based exercise, might have poor long-term benefits for maintaining physical performance in older adults. Geriatr Gerontol Int 2017; 17: 2116-2123. © 2017 Japan Geriatrics Society.

  14. Toric Geometry of the Regular Convex Polyhedra

    Directory of Open Access Journals (Sweden)

    Fiammetta Battaglia

    2017-01-01

    Full Text Available We describe symplectic and complex toric spaces associated with the five regular convex polyhedra. The regular tetrahedron and the cube are rational and simple, the regular octahedron is not simple, the regular dodecahedron is not rational, and the regular icosahedron is neither simple nor rational. We remark that the last two cases cannot be treated via standard toric geometry.

  15. Word regularity affects orthographic learning.

    Science.gov (United States)

    Wang, Hua-Chen; Castles, Anne; Nickels, Lyndsey

    2012-01-01

    Share's self-teaching hypothesis proposes that orthographic representations are acquired via phonological decoding. A key, yet untested, prediction of this theory is that there should be an effect of word regularity on the number and quality of word-specific orthographic representations that children acquire. Thirty-four Grade 2 children were exposed to the sound and meaning of eight novel words and were then presented with those words in written form in short stories. Half the words were assigned regular pronunciations and half irregular pronunciations. Lexical decision and spelling tasks conducted 10 days later revealed that the children's orthographic representations of the regular words appeared to be stronger and more extensive than those of the irregular words.

  16. Vertex-deleted subgraphs and regular factors from regular graph☆

    Science.gov (United States)

    Lu, Hongliang; Wang, Wei; Bai, Bing

    2011-01-01

    Let k, m, and r be three integers such that 2≤k≤m≤r. Let G be a 2r-regular, 2m-edge-connected graph of odd order. We obtain some sufficient conditions for G−v to contain a k-factor for all v∈V(G). PMID:21984842

  17. Hyperspectral Image Recovery via Hybrid Regularization.

    Science.gov (United States)

    Arablouei, Reza; de Hoog, Frank

    2016-09-27

    Natural images tend to mostly consist of smooth regions with individual pixels having highly correlated spectra. This information can be exploited to recover hyperspectral images of natural scenes from their incomplete and noisy measurements. To perform the recovery while taking full advantage of the prior knowledge, we formulate a composite cost function containing a square-error data-fitting term and two distinct regularization terms pertaining to spatial and spectral domains. The regularization for the spatial domain is the sum of total-variation of the image frames corresponding to all spectral bands. The regularization for the spectral domain is the ��������-norm of the coefficient matrix obtained by applying a suitable sparsifying transform to the spectra of the pixels. We use an accelerated proximal-subgradient method to minimize the formulated cost function. We analyse the performance of the proposed algorithm and prove its convergence. Numerical simulations using real hyperspectral images exhibit that the proposed algorithm offers an excellent recovery performance with a number of measurements that is only a small fraction of the hyperspectral image data size. Simulation results also show that the proposed algorithm significantly outperforms an accelerated proximal-gradient algorithm that solves the classical basis-pursuit denoising problem to recover the hyperspectral image.

  18. Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function.

    Science.gov (United States)

    Lai, Frank Pui-Ling; Lau, Sin-Ting; Wong, John Kwong-Leong; Gui, Hongsheng; Wang, Reeson Xu; Zhou, Tingwen; Lai, Wing Hon; Tse, Hung-Fat; Tam, Paul Kwong-Hang; Garcia-Barcelo, Maria-Mercedes; Ngan, Elly Sau-Wai

    2017-07-01

    Hirschsprung disease is caused by failure of enteric neural crest cells (ENCCs) to fully colonize the bowel, leading to bowel obstruction and megacolon. Heterozygous mutations in the coding region of the RET gene cause a severe form of Hirschsprung disease (total colonic aganglionosis). However, 80% of HSCR patients have short-segment Hirschsprung disease (S-HSCR), which has not been associated with genetic factors. We sought to identify mutations associated with S-HSCR, and used the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene editing system to determine how mutations affect ENCC function. We created induced pluripotent stem cell (iPSC) lines from 1 patient with total colonic aganglionosis (with the G731del mutation in RET) and from 2 patients with S-HSCR (without a RET mutation), as well as RET +/- and RET -/- iPSCs. IMR90-iPSC cells were used as the control cell line. Migration and differentiation capacities of iPSC-derived ENCCs were analyzed in differentiation and migration assays. We searched for mutation(s) associated with S-HSCR by combining genetic and transcriptome data from patient blood- and iPSC-derived ENCCs, respectively. Mutations in the iPSCs were corrected using the CRISPR/Cas9 system. ENCCs derived from all iPSC lines, but not control iPSCs, had defects in migration and neuronal lineage differentiation. RET mutations were associated with differentiation and migration defects of ENCCs in vitro. Genetic and transcriptome analyses associated a mutation in the vinculin gene (VCL M209L) with S-HSCR. CRISPR/Cas9 correction of the RET G731del and VCL M209L mutations in iPSCs restored the differentiation and migration capacities of ENCCs. We identified mutations in VCL associated with S-HSCR. Correction of this mutation in iPSC using CRISPR/Cas9 editing, as well as the RET G731del mutation that causes Hirschsprung disease with total colonic aganglionosis, restored ENCC function. Our study demonstrates how human iPSCs can

  19. Regularized algorithm for Raman lidar data processing.

    Science.gov (United States)

    Shcherbakov, Valery

    2007-08-01

    A regularized algorithm that has the potential to improve the quality of Raman lidar data processing is presented. Compared to the conventional scheme, the proposed algorithm has the advantage, which results from the fact that it is based on a well-posed procedure. That is, the profile of the aerosol backscatter coefficient is computed directly, using the explicit relationships, without numerical differentiation. Thereafter, the profile of the lidar ratio is retrieved as a regularized solution of a first-kind Volterra integral equation. Once these two steps have been completed, the profile of the aerosol extinction coefficient is computed by a straightforward multiplication. The numerical simulations demonstrated that the proposed algorithm provides good accuracy and resolution of aerosol profile retrievals. The error analysis showed that the retrieved profiles are continuous functions of the measurement errors and of the a priori information uncertainties.

  20. Extreme values, regular variation and point processes

    CERN Document Server

    Resnick, Sidney I

    1987-01-01

    Extremes Values, Regular Variation and Point Processes is a readable and efficient account of the fundamental mathematical and stochastic process techniques needed to study the behavior of extreme values of phenomena based on independent and identically distributed random variables and vectors It presents a coherent treatment of the distributional and sample path fundamental properties of extremes and records It emphasizes the core primacy of three topics necessary for understanding extremes the analytical theory of regularly varying functions; the probabilistic theory of point processes and random measures; and the link to asymptotic distribution approximations provided by the theory of weak convergence of probability measures in metric spaces The book is self-contained and requires an introductory measure-theoretic course in probability as a prerequisite Almost all sections have an extensive list of exercises which extend developments in the text, offer alternate approaches, test mastery and provide for enj...

  1. Empirical laws, regularity and necessity

    NARCIS (Netherlands)

    Koningsveld, H.

    1973-01-01

    In this book I have tried to develop an analysis of the concept of an empirical law, an analysis that differs in many ways from the alternative analyse's found in contemporary literature dealing with the subject.

    1 am referring especially to two well-known views, viz. the regularity and

  2. Regularization in Matrix Relevance Learning

    NARCIS (Netherlands)

    Schneider, Petra; Bunte, Kerstin; Stiekema, Han; Hammer, Barbara; Villmann, Thomas; Biehl, Michael

    A In this paper, we present a regularization technique to extend recently proposed matrix learning schemes in learning vector quantization (LVQ). These learning algorithms extend the concept of adaptive distance measures in LVQ to the use of relevance matrices. In general, metric learning can

  3. Regularity of conservative inductive limits

    Directory of Open Access Journals (Sweden)

    Jan Kucera

    1999-01-01

    Full Text Available A sequentially complete inductive limit of Fréchet spaces is regular, see [3]. With a minor modification, this property can be extended to inductive limits of arbitrary locally convex spaces under an additional assumption of conservativeness.

  4. Regular Matroids with Graphic Cocircuits

    OpenAIRE

    Papalamprou, Konstantinos; Pitsoulis, Leonidas

    2009-01-01

    We introduce the notion of graphic cocircuits and show that a large class of regular matroids with graphic cocircuits belongs to the class of signed-graphic matroids. Moreover, we provide an algorithm which determines whether a cographic matroid with graphic cocircuits is signed-graphic or not.

  5. Interval matrices: Regularity generates singularity

    Czech Academy of Sciences Publication Activity Database

    Rohn, Jiří; Shary, S.P.

    2018-01-01

    Roč. 540, 1 March (2018), s. 149-159 ISSN 0024-3795 Institutional support: RVO:67985807 Keywords : interval matrix * regularity * singularity * P-matrix * absolute value equation * diagonally singilarizable matrix Subject RIV: BA - General Mathematics Impact factor: 0.973, year: 2016

  6. Explicit formulas for regularized products and series

    CERN Document Server

    Jorgenson, Jay; Goldfeld, Dorian

    1994-01-01

    The theory of explicit formulas for regularized products and series forms a natural continuation of the analytic theory developed in LNM 1564. These explicit formulas can be used to describe the quantitative behavior of various objects in analytic number theory and spectral theory. The present book deals with other applications arising from Gaussian test functions, leading to theta inversion formulas and corresponding new types of zeta functions which are Gaussian transforms of theta series rather than Mellin transforms, and satisfy additive functional equations. Their wide range of applications includes the spectral theory of a broad class of manifolds and also the theory of zeta functions in number theory and representation theory. Here the hyperbolic 3-manifolds are given as a significant example.

  7. Regular languages, regular grammars and automata in splicing systems

    Science.gov (United States)

    Mohamad Jan, Nurhidaya; Fong, Wan Heng; Sarmin, Nor Haniza

    2013-04-01

    Splicing system is known as a mathematical model that initiates the connection between the study of DNA molecules and formal language theory. In splicing systems, languages called splicing languages refer to the set of double-stranded DNA molecules that may arise from an initial set of DNA molecules in the presence of restriction enzymes and ligase. In this paper, some splicing languages resulted from their respective splicing systems are shown. Since all splicing languages are regular, languages which result from the splicing systems can be further investigated using grammars and automata in the field of formal language theory. The splicing language can be written in the form of regular languages generated by grammar. Besides that, splicing systems can be accepted by automata. In this research, two restriction enzymes are used in splicing systems namely BfuCI and NcoI.

  8. Temporal regularity in speech perception: Is regularity beneficial or deleterious?

    Science.gov (United States)

    Geiser, Eveline; Shattuck-Hufnagel, Stefanie

    2012-04-01

    Speech rhythm has been proposed to be of crucial importance for correct speech perception and language learning. This study investigated the influence of speech rhythm in second language processing. German pseudo-sentences were presented to participants in two conditions: 'naturally regular speech rhythm' and an 'emphasized regular rhythm'. Nine expert English speakers with 3.5±1.6 years of German training repeated each sentence after hearing it once over headphones. Responses were transcribed using the International Phonetic Alphabet and analyzed for the number of correct, false and missing consonants as well as for consonant additions. The over-all number of correct reproductions of consonants did not differ between the two experimental conditions. However, speech rhythmicization significantly affected the serial position curve of correctly reproduced syllables. The results of this pilot study are consistent with the view that speech rhythm is important for speech perception.

  9. Regular and conformal regular cores for static and rotating solutions

    Energy Technology Data Exchange (ETDEWEB)

    Azreg-Aïnou, Mustapha

    2014-03-07

    Using a new metric for generating rotating solutions, we derive in a general fashion the solution of an imperfect fluid and that of its conformal homolog. We discuss the conditions that the stress–energy tensors and invariant scalars be regular. On classical physical grounds, it is stressed that conformal fluids used as cores for static or rotating solutions are exempt from any malicious behavior in that they are finite and defined everywhere.

  10. Recursively-regular subdivisions and applications

    Directory of Open Access Journals (Sweden)

    Rafel Jaume

    2016-05-01

    Full Text Available We generalize regular subdivisions (polyhedral complexes resulting from the projection of the lower faces of a polyhedron introducing the class of recursively-regular subdivisions. Informally speaking, a recursively-regular subdivision is a subdivision that can be obtained by splitting some faces of a regular subdivision by other regular subdivisions (and continue recursively. We also define the finest regular coarsening and the regularity tree of a polyhedral complex. We prove that recursively-regular subdivisions are not necessarily connected by flips and that they are acyclic with respect to the in-front relation. We show that the finest regular coarsening of a subdivision can be efficiently computed, and that whether a subdivision is recursively regular can be efficiently decided. As an application, we also extend a theorem known since 1981 on illuminating space by cones and present connections of recursive regularity to tensegrity theory and graph-embedding problems.     

  11. From inactive to regular jogger

    DEFF Research Database (Denmark)

    Lund-Cramer, Pernille; Brinkmann Løite, Vibeke; Bredahl, Thomas Viskum Gjelstrup

    to translate intention into regular behavior. TTM: Informants expressed rapid progression from the pre-contemplation to the action stage caused by an early shift in the decisional balance towards advantages overweighing disadvantages. This was followed by a continuous improvement in self-efficacy, which...... jogging-related self-efficacy, and deployment of realistic goal setting was significant in the achievement of regular jogging behavior. Cognitive factors included a positive change in both affective and instrumental beliefs about jogging. Expectations from society and social relations had limited effect...... health, and well-being. An experience-driven change in affective beliefs contributed to the shift in the intention. Informants’ initial expectations to own jogging abilities were realistic and modest, which in combination with a GPS-training watch applied sufficient perceived behavioral control...

  12. Physical model of dimensional regularization

    Energy Technology Data Exchange (ETDEWEB)

    Schonfeld, Jonathan F.

    2016-12-15

    We explicitly construct fractals of dimension 4-ε on which dimensional regularization approximates scalar-field-only quantum-field theory amplitudes. The construction does not require fractals to be Lorentz-invariant in any sense, and we argue that there probably is no Lorentz-invariant fractal of dimension greater than 2. We derive dimensional regularization's power-law screening first for fractals obtained by removing voids from 3-dimensional Euclidean space. The derivation applies techniques from elementary dielectric theory. Surprisingly, fractal geometry by itself does not guarantee the appropriate power-law behavior; boundary conditions at fractal voids also play an important role. We then extend the derivation to 4-dimensional Minkowski space. We comment on generalization to non-scalar fields, and speculate about implications for quantum gravity. (orig.)

  13. How to quantify student's regularity?

    OpenAIRE

    Shirvani Boroujeni, Mina; Sharma, Kshitij; Kidzinski, Lukasz; Lucignano, Lorenzo; Dillenbourg, Pierre

    2016-01-01

    Studies carried out in classroom-based learning context, have consistently shown a positive relation between students' conscientiousness and their academic success. We hypothesize that time management and regularity are main constructing blocks of students' conscientiousness in the context of online education. In online education, despite intuitive arguments supporting on-demand courses as more flexible delivery of knowledge, completion rate is higher in the courses with rigid temporal constr...

  14. (2 + 1)-dimensional regular black holes with nonlinear electrodynamics sources

    OpenAIRE

    He, Yun; Ma, Meng-Sen(Department of Physics, Shanxi Datong University, Datong 037009, China)

    2017-01-01

    On the basis of two requirements: the avoidance of the curvature singularity and the Maxwell theory as the weak field limit of the nonlinear electrodynamics, we find two restricted conditions on the metric function of (2+1) -dimensional regular black hole in general relativity coupled with nonlinear electrodynamics sources. By the use of the two conditions, we obtain a general approach to construct (2+1) -dimensional regular black holes. In this manner, we construct four (2+1) -dimensional re...

  15. Estimation of the global regularity of a multifractional Brownian motion

    OpenAIRE

    Lebovits, Joachim; Podolskij, Mark

    2016-01-01

    This paper presents a new estimator of the global regularity index of a multifractional Brownian motion. Our estimation method is based upon a ratio statistic, which compares the realized global quadratic variation of a multifractional Brownian motion at two different frequencies. We show that a logarithmic transformation of this statistic converges in probability to the minimum of the Hurst functional parameter, which is, under weak assumptions, identical to the global regularity index of th...

  16. Tree games with regular objectives

    Directory of Open Access Journals (Sweden)

    Marcin Przybyłko

    2014-08-01

    Full Text Available We study tree games developed recently by Matteo Mio as a game interpretation of the probabilistic μ-calculus. With expressive power comes complexity. Mio showed that tree games are able to encode Blackwell games and, consequently, are not determined under deterministic strategies. We show that non-stochastic tree games with objectives recognisable by so-called game automata are determined under deterministic, finite memory strategies. Moreover, we give an elementary algorithmic procedure which, for an arbitrary regular language L and a finite non-stochastic tree game with a winning objective L decides if the game is determined under deterministic strategies.

  17. Academic Training Lecture - Regular Programme

    CERN Multimedia

    PH Department

    2011-01-01

    Regular Lecture Programme 9 May 2011 ACT Lectures on Detectors - Inner Tracking Detectors by Pippa Wells (CERN) 10 May 2011 ACT Lectures on Detectors - Calorimeters (2/5) by Philippe Bloch (CERN) 11 May 2011 ACT Lectures on Detectors - Muon systems (3/5) by Kerstin Hoepfner (RWTH Aachen) 12 May 2011 ACT Lectures on Detectors - Particle Identification and Forward Detectors by Peter Krizan (University of Ljubljana and J. Stefan Institute, Ljubljana, Slovenia) 13 May 2011 ACT Lectures on Detectors - Trigger and Data Acquisition (5/5) by Dr. Brian Petersen (CERN) from 11:00 to 12:00 at CERN ( Bldg. 222-R-001 - Filtration Plant )

  18. Regular nanofabrics in emerging technologies

    CERN Document Server

    Jamaa, M Haykel Ben

    2011-01-01

    ""Regular Nanofabrics in Emerging Technologies"" gives a deep insight into both fabrication and design aspects of emerging semiconductor technologies, that represent potential candidates for the post-CMOS era. Its approach is unique, across different fields, and it offers a synergetic view for a public of different communities ranging from technologists, to circuit designers, and computer scientists. The book presents two technologies as potential candidates for future semiconductor devices and systems and it shows how fabrication issues can be addressed at the design level and vice versa. The

  19. Regularization methods in Banach spaces

    CERN Document Server

    Schuster, Thomas; Hofmann, Bernd; Kazimierski, Kamil S

    2012-01-01

    Regularization methods aimed at finding stable approximate solutions are a necessary tool to tackle inverse and ill-posed problems. Usually the mathematical model of an inverse problem consists of an operator equation of the first kind and often the associated forward operator acts between Hilbert spaces. However, for numerous problems the reasons for using a Hilbert space setting seem to be based rather on conventions than on an approprimate and realistic model choice, so often a Banach space setting would be closer to reality. Furthermore, sparsity constraints using general Lp-norms or the B

  20. Regular capacities on metrizable spaces

    Directory of Open Access Journals (Sweden)

    T. M. Cherkovskyi

    2014-07-01

    Full Text Available It is proved that for a (not necessarily compact metric space: the metrics on the space of capacities in the sense of Zarichnyi and Prokhorov are equal; completeness of the space of capacities is equivalent to completeness of the original space. It is shown that for the capacities on metrizable spaces the properties of $\\omega$-smoothness and of $\\tau$-smoothness are equivalent precisely on the separable spaces, and the properties of $\\omega$-smoothness and of regularity w.r.t. some (then w.r.t. any admissible metric are equivalent precisely on the compact spaces.

  1. A twelve-week randomized controlled study of the cognitive-behavioral Integrated Psychological Therapy program: positive effect on the social functioning of schizophrenic patients Estudo controlado randomizado de 12 semanas do programa cognitivo-comportamental IPT (Terapia Psicológica Integrada com efeito positivo sobre o funcionamento social em pacientes com esquizofrenia

    Directory of Open Access Journals (Sweden)

    Marilene Zimmer

    2007-06-01

    designado para avaliar o efeito de 12 sessões semanais do programa cognitivo-comportamental IPT (Integrated Psychological Therapy - Integriertes psychologisches Therapieprogramm für schizophrene Patienten - Terapia Psicológica Integrada, comparado ao tratamento usual sobre o funcionamento cognitivo, ajustamento social e qualidade de vida em pacientes ambulatoriais com esquizofrenia. MÉTODO: Cinqüenta e seis pacientes ambulatoriais adultos (idade entre 18 e 65 anos com diagnóstico de esquizofrenia pela CID-10, foram aleatoriamente designados para dois grupos: intervenção ativa (IPT e tratamento usual (grupo controle. As diferenças de medidas de resultados foram em qualidade de vida (WHOQOL-bref, cognição (Mini-Mental State Examination e word-span, funcionamento global (Global Assessment of Functioning-DMS-IV, funcionamento social (Social and Occupational Functioning Assessment Scale-DSM-IV e ajustamento social (Social Adjustment Scale. RESULTADOS: Os achados sugerem que 12 sessões do programa IPT mostraram um efeito positivo sobre várias medidas de resultado comparado ao grupo controle (tratamento usual: cognição nos domínios de orientação no tempo e no espaço (p = 0,045 e memória (p = 0,031; ajustamento social geral (p = 0,037, lazer e vida social (p = 0,051, relações familiares (p = 0,008; funcionamento global (p = 0,000; funcionamento sócio-ocupacional (p = 0,000; e qualidade de vida no domínio psicológico (p = 0,021. CONCLUSÃO: A intervenção cognitivo-comportamental de 12 sessões do IPT demonstrou superioridade de efeito sobre cognição, ajustamento social e qualidade de vida comparado ao tratamento usual. Estudos com amostras maiores, maior tempo de seguimento (follow-up e medidas adicionais de desfechos são necessários para avaliar efeitos específicos sobre dimensões de funcionamento cognitivo, social e qualidade de vida em esquizofrênicos.

  2. Regularization destriping of remote sensing imagery

    Directory of Open Access Journals (Sweden)

    R. Basnayake

    2017-07-01

    Full Text Available We illustrate the utility of variational destriping for ocean color images from both multispectral and hyperspectral sensors. In particular, we examine data from a filter spectrometer, the Visible Infrared Imaging Radiometer Suite (VIIRS on the Suomi National Polar Partnership (NPP orbiter, and an airborne grating spectrometer, the Jet Population Laboratory's (JPL hyperspectral Portable Remote Imaging Spectrometer (PRISM sensor. We solve the destriping problem using a variational regularization method by giving weights spatially to preserve the other features of the image during the destriping process. The target functional penalizes the neighborhood of stripes (strictly, directionally uniform features while promoting data fidelity, and the functional is minimized by solving the Euler–Lagrange equations with an explicit finite-difference scheme. We show the accuracy of our method from a benchmark data set which represents the sea surface temperature off the coast of Oregon, USA. Technical details, such as how to impose continuity across data gaps using inpainting, are also described.

  3. Regularization destriping of remote sensing imagery

    Science.gov (United States)

    Basnayake, Ranil; Bollt, Erik; Tufillaro, Nicholas; Sun, Jie; Gierach, Michelle

    2017-07-01

    We illustrate the utility of variational destriping for ocean color images from both multispectral and hyperspectral sensors. In particular, we examine data from a filter spectrometer, the Visible Infrared Imaging Radiometer Suite (VIIRS) on the Suomi National Polar Partnership (NPP) orbiter, and an airborne grating spectrometer, the Jet Population Laboratory's (JPL) hyperspectral Portable Remote Imaging Spectrometer (PRISM) sensor. We solve the destriping problem using a variational regularization method by giving weights spatially to preserve the other features of the image during the destriping process. The target functional penalizes the neighborhood of stripes (strictly, directionally uniform features) while promoting data fidelity, and the functional is minimized by solving the Euler-Lagrange equations with an explicit finite-difference scheme. We show the accuracy of our method from a benchmark data set which represents the sea surface temperature off the coast of Oregon, USA. Technical details, such as how to impose continuity across data gaps using inpainting, are also described.

  4. Regular Exercisers Have Stronger Pelvic Floor Muscles than Non-Regular Exercisers at Midpregnancy.

    Science.gov (United States)

    Bø, Kari; Ellstrøm Engh, Marie; Hilde, Gunvor

    2017-12-26

    Today, all healthy pregnant women are encouraged to be physically active throughout pregnancy, with recommendations to participate in at least 30 min of aerobic activity on most days of the week, in addition to perform strength training of the major muscle groups 2-3 days per week, and also pelvic floor muscle training. There is, however, an ongoing debate whether general physical activity enhances or declines pelvic floor muscle function. To compare vaginal resting pressure, pelvic floor muscle strength and endurance in regular exercisers (exercise ≥ 30 minutes ≥ 3 times per week) and non-exercisers at mid-pregnancy. Furthermore, to assess whether regular general exercise or pelvic floor muscle strength was associated with urinary incontinence. This was a cross-sectional study at mean gestational week 20.9 (± 1.4) including 218 nulliparous pregnant women, mean age 28.6 years (range 19-40) and pre-pregnancy body mass index 23.9 kg/m 2 (SD 4.0). Vaginal resting pressure, pelvic floor muscle strength and pelvic floor muscle endurance were measured by a high precision pressure transducer connected to a vaginal balloon. International Consultation on Incontinence Questionnaire Urinary Incontinence Short Form was used to assess urinary incontinence. Differences between groups were analyzed using Independent Sample T-test. Linear regression analysis was conducted to adjust for pre-pregnancy body mass index, age, smoking during pregnancy and regular pelvic floor muscle training during pregnancy. P-value was set to ≤ 0.05. Regular exercisers had statistically significant stronger ( mean 6.4 cm H 2 O (95% CI: 1.7, 11.2)) and more enduring ( mean 39.9 cm H 2 Osec (95% CI: 42.2, 75.7)) pelvic floor muscles. Only pelvic floor muscle strength remained statistically significant, when adjusting for possible confounders. Pelvic floor muscle strength and not regular general exercise was associated with urinary continence (adjusted B: -6.4 (95% CI: -11.5, -1.4)). Regular

  5. Convergence and Fluctuations of Regularized Tyler Estimators

    Science.gov (United States)

    Kammoun, Abla; Couillet, Romain; Pascal, Ferderic; Alouini, Mohamed-Slim

    2016-02-01

    This article studies the behavior of regularized Tyler estimators (RTEs) of scatter matrices. The key advantages of these estimators are twofold. First, they guarantee by construction a good conditioning of the estimate and second, being a derivative of robust Tyler estimators, they inherit their robustness properties, notably their resilience to the presence of outliers. Nevertheless, one major problem that poses the use of RTEs in practice is represented by the question of setting the regularization parameter $\\rho$. While a high value of $\\rho$ is likely to push all the eigenvalues away from zero, it comes at the cost of a larger bias with respect to the population covariance matrix. A deep understanding of the statistics of RTEs is essential to come up with appropriate choices for the regularization parameter. This is not an easy task and might be out of reach, unless one considers asymptotic regimes wherein the number of observations $n$ and/or their size $N$ increase together. First asymptotic results have recently been obtained under the assumption that $N$ and $n$ are large and commensurable. Interestingly, no results concerning the regime of $n$ going to infinity with $N$ fixed exist, even though the investigation of this assumption has usually predated the analysis of the most difficult $N$ and $n$ large case. This motivates our work. In particular, we prove in the present paper that the RTEs converge to a deterministic matrix when $n\\to\\infty$ with $N$ fixed, which is expressed as a function of the theoretical covariance matrix. We also derive the fluctuations of the RTEs around this deterministic matrix and establish that these fluctuations converge in distribution to a multivariate Gaussian distribution with zero mean and a covariance depending on the population covariance and the parameter $\\rho$.

  6. Convergence and fluctuations of Regularized Tyler estimators

    KAUST Repository

    Kammoun, Abla

    2015-10-26

    This article studies the behavior of regularized Tyler estimators (RTEs) of scatter matrices. The key advantages of these estimators are twofold. First, they guarantee by construction a good conditioning of the estimate and second, being a derivative of robust Tyler estimators, they inherit their robustness properties, notably their resilience to the presence of outliers. Nevertheless, one major problem that poses the use of RTEs in practice is represented by the question of setting the regularization parameter p. While a high value of p is likely to push all the eigenvalues away from zero, it comes at the cost of a larger bias with respect to the population covariance matrix. A deep understanding of the statistics of RTEs is essential to come up with appropriate choices for the regularization parameter. This is not an easy task and might be out of reach, unless one considers asymptotic regimes wherein the number of observations n and/or their size N increase together. First asymptotic results have recently been obtained under the assumption that N and n are large and commensurable. Interestingly, no results concerning the regime of n going to infinity with N fixed exist, even though the investigation of this assumption has usually predated the analysis of the most difficult N and n large case. This motivates our work. In particular, we prove in the present paper that the RTEs converge to a deterministic matrix when n → ∞ with N fixed, which is expressed as a function of the theoretical covariance matrix. We also derive the fluctuations of the RTEs around this deterministic matrix and establish that these fluctuations converge in distribution to a multivariate Gaussian distribution with zero mean and a covariance depending on the population covariance and the parameter.

  7. Efeito da fisioterapia no desempenho funcional do membro superior no pós-operatório de câncer de mama = Physical therapy effects on upper functional performance after breast cancer surgery

    Directory of Open Access Journals (Sweden)

    Rett, Mariana Tirolli

    2013-01-01

    Full Text Available Objetivo: Verificar o efeito da fisioterapia na amplitude de movimento (ADM e no desempenho funcional do membro superior homolateral no pós-operatório para tratamento do câncer de mama e correlacionar estas variáveis. Materiais e Métodos: Série de casos envolvendo mulheres submetidas à cirurgia unilateral para tratamento do câncer de mama, associado à linfadenectomia axilar. A ADM foi mensurada nos dois membros superiores através da goniometria, sendo o membro contralateral à cirurgia considerado o controle. O desempenho funcional foi avaliado pelo questionário “deficiência do ombro, braço e mão” (DASH. O protocolo de fisioterapia foi de 10 sessões de alongamentos e exercícios ativo-livres dos MMSS. A goniometria e os escores do DASH foram comparados pelo Wilcoxon signed rank test e para correlacionar estas variáveis foi utilizado o teste de correlação de Spearman, adotando significância de 5%. Resultados: Foram incluídas 10 mulheres com mediana de idade de 52,5 (41,7-59,5 anos, sendo sete submetidas à mastectomia radical e três à quadrandectomia. Encontrou-se aumento significativo da ADM de todos os movimentos avaliados, principalmente da flexão, abdução e rotação externa (p=0,005. Ao final do estudo, a ADM dos membros superiores não apresentou diferença significativa. O escore do DASH reduziu significativamente 38,9 (36-46,4 para 21,2 (9,5-23,8, (p=0,005. Não foi observada nenhuma associação entre a ADM e o escore do DASH. Conclusão: Verificou-se após 10 sessões de fisioterapia houve melhora significativa da amplitude de movimento e do desempenho funcional do membro superior homolateral à cirurgia, mas nenhuma correlação foi encontrada entre as variáveis estudadas

  8. Efeitos do Tratamento Crônico com Celecoxibe ou Indometacina na Função Renal de Ratos Submetidos a um Modelo Experimental de Doença Renal Crônica / Effects of Chronic Treatment with Celecoxib or Indomethacin on Renal Function in Rats Subjected to an Experimental Model of Chronic Kidney Diseas

    Directory of Open Access Journals (Sweden)

    Renato Maduro Pereira

    2014-12-01

    Full Text Available Objetivo: avaliar os efeitos do tratamento crônico com Celecoxibe e Indometacina sobre a função renal de ratos. Materiais e Métodos: Os ratos foram submetidos a um modelo experimental de doença renal crônica moderada (nefrectomia ¾, randomizados em três grupos, alocados em gaiolas metabólicas individuais e receberam administrações distintas durante quatorze dias por gavagem: 1- Água destilada, 2- Celecoxibe 200mg/Kg e 3- Indometacina 5mg/Kg. Foram avaliados diariamente parâmetros como peso, ingesta hídrica, alimentar, débito urinário e ao final do experimento, foram coletadas amostras de urina e sangue para dosagens de ureia, creatinina sérica e urinária, glicemia e clearance de creatinina. Resultados: Apesar de não haver diferença significativa no clearance de creatinina entre os grupos, a maior mortalidade no grupo indometacina pode evidenciar que seus efeitos adversos na função renal são mais importantes se comparados aos do celecoxibe. Conclusão: O celecoxibe demostrou, sob as condições experimentais utilizadas, ser seguro em ratos submetidos à doença renal crônica moderada. Observou-se aumento significativo na mortalidade do grupo Indometacina. Objectives: to evaluate the effect of chronic treatment with Celecoxib and indomethacin on renal function in rats. Methodology: The rats were subjected to an experimental model of moderate chronic kidney disease ( ¾ nephrectomy were randomized into three groups allocated in individual metabolic cages and received separate administrations during fourteen days by gavage : 1- Distilled water, 2- Celecoxib 200mg/Kg and 3- Indomethacin 5mg/Kg . Parameters such as body weight, water intake, food , urine , and urine output was evaluated at the end of the experiment , blood and urine samples were collected for serum urea , serum and urinary creatinine, glucose and creatinine clearance were assessed daily . Results: Although there was no significant difference in creatinine

  9. Prefrontal-hippocampal dynamics involved in learning regularities across episodes.

    Science.gov (United States)

    Doeller, Christian F; Opitz, Bertram; Krick, Christoph M; Mecklinger, Axel; Reith, Wolfgang

    2005-08-01

    Using functional magnetic resonance imaging, the neural correlates of context-specific memories and invariant memories about regularities across episodes were investigated. Volunteers had to learn conjunctions between objects and positions. In an invariant learning condition, positions were held constant, enabling subjects to learn regularities across trials. By contrast, in a context-specific condition object-position conjunctions were trial unique. Performance increase in the invariant learning condition was paralleled by a learning-related increase of inferior frontal gyrus activation and ventral striatal activation and a decrease of hippocampus activation. Conversely, in the context-specific condition hippocampal activation was constant across trials. We argue that the learning-related hippocampal activation pattern might be due to reduced relational binding requirements once regularities are extracted. Furthermore, we propose that the learning-related prefrontal modulation reflects the requirement to extract and maintain regularities across trials and the adjustment of object-position conjunctions on the basis of the extracted knowledge. Finally, our data suggest that the ventral striatum encodes the increased predictability of spatial features as a function of learning. Taken together, these results indicate a transition of the relative roles of distinct brain regions during learning regularities across multiple episodes: regularity learning is characterized by a shift from a hippocampal to a prefrontal-striatal brain system.

  10. Local conservative regularizations of compressible MHD and neutral flows

    CERN Document Server

    Krishnaswami, Govind S; Thyagaraja, Anantanarayanan

    2016-01-01

    Ideal systems like MHD and Euler flow may develop singularities in vorticity (w = curl v). Viscosity and resistivity provide dissipative regularizations of the singularities. In this paper we propose a minimal, local, conservative, nonlinear, dispersive regularization of compressible flow and ideal MHD, in analogy with the KdV regularization of the 1D kinematic wave equation. This work extends and significantly generalizes earlier work on incompressible Euler and ideal MHD. It involves a micro-scale cutoff length lambda which is a function of density, unlike in the incompressible case. In MHD, it can be taken to be of order the electron collisionless skin depth c/omega_pe. Our regularization preserves the symmetries of the original systems, and with appropriate boundary conditions, leads to associated conservation laws. Energy and enstrophy are subject to a priori bounds determined by initial data in contrast to the unregularized systems. A Hamiltonian and Poisson bracket formulation is developed and applied ...

  11. Regularization of regional gravity fields from GOCE data

    Science.gov (United States)

    Naeimi, M.; Flury, J.; Brieden, P.

    2014-12-01

    Regional gravity field recovery in spherical radial base functions is a strongly ill-posed problem. The ill-posedness is mainly due the restriction of observations as well as the base functions to a specific area. We investigate this ill-posedness as well as the related regularization process. We compare four different methods for the choice of regularization parameter and discuss their characteristics. Moreover, two different kinds of shape coefficients for the spherical radial base functions are used to assess the impact of shape coefficients on the regularization process. These shape coefficients are the Shannon coefficients with no smoothing properties and the Spline kernel with smoothing features. As the data set, we use two months of real GOCE ultra-sensitive gravity gradient components which are Txx, Tyy, Tzz and Txz. The regional solutions are considered in Amazon. Our results indicate, that the method used for the choice of regularization parameter is directly influenced by the shape of spherical radial base functions. In addition we conclude, that the Shannon kernel along with a proper regularization approach delivers satisfactory results with physically meaningful coefficients.

  12. Modeling polycrystals with regular polyhedra

    Directory of Open Access Journals (Sweden)

    Paulo Rangel Rios

    2006-06-01

    Full Text Available Polycrystalline structure is of paramount importance to materials science and engineering. It provides an important example of a space-filling irregular network structure that also occurs in foams as well as in certain biological tissues. Therefore, seeking an accurate description of the characteristics of polycrystals is of fundamental importance. Recently, one of the authors (MEG published a paper in which a method was devised of representation of irregular networks by regular polyhedra with curved faces. In Glicksman's method a whole class of irregular polyhedra with a given number of faces, N, is represented by a single symmetrical polyhedron with N curved faces. This paper briefly describes the topological and metric properties of these special polyhedra. They are then applied to two important problems of irregular networks: the dimensionless energy 'cost' of irregular networks, and the derivation of a 3D analogue of the von Neumann-Mullins equation for the growth rate of grains in a polycrystal.

  13. Bayesian regularization of neural networks.

    Science.gov (United States)

    Burden, Frank; Winkler, Dave

    2008-01-01

    Bayesian regularized artificial neural networks (BRANNs) are more robust than standard back-propagation nets and can reduce or eliminate the need for lengthy cross-validation. Bayesian regularization is a mathematical process that converts a nonlinear regression into a "well-posed" statistical problem in the manner of a ridge regression. The advantage of BRANNs is that the models are robust and the validation process, which scales as O(N2) in normal regression methods, such as back propagation, is unnecessary. These networks provide solutions to a number of problems that arise in QSAR modeling, such as choice of model, robustness of model, choice of validation set, size of validation effort, and optimization of network architecture. They are difficult to overtrain, since evidence procedures provide an objective Bayesian criterion for stopping training. They are also difficult to overfit, because the BRANN calculates and trains on a number of effective network parameters or weights, effectively turning off those that are not relevant. This effective number is usually considerably smaller than the number of weights in a standard fully connected back-propagation neural net. Automatic relevance determination (ARD) of the input variables can be used with BRANNs, and this allows the network to "estimate" the importance of each input. The ARD method ensures that irrelevant or highly correlated indices used in the modeling are neglected as well as showing which are the most important variables for modeling the activity data. This chapter outlines the equations that define the BRANN method plus a flowchart for producing a BRANN-QSAR model. Some results of the use of BRANNs on a number of data sets are illustrated and compared with other linear and nonlinear models.

  14. EFEITOS DAS PISTAS VISUAIS NA MARCHA EM PACIENTES COM PARKINSON

    Directory of Open Access Journals (Sweden)

    Ana Sousa

    2015-05-01

    Full Text Available A  doença de Parkinson (DP é uma doença neurodegenerativa crónica, resultante de disfunções nos gânglios basais, localizados no cérebro, relacionados com o controle motor. Um dos sintomas mais incapacitantes da DP é a festinação, caracterizada pela pobreza dos movimentos, passos curtos, pés rentes ao chão e uma diminuição da velocidade. Investigações recentes recorrem ao treino da marcha com pistas sensoriais, tais como as visuais, para a reabilitação do congelamento ou freezing da marcha parkinsoniana, com o objetivo de desviar a função dos núcleos da base com o fim de regular a função motora deficitáriaObjetivo: Esta revisão sistémica da Literatura foi desenvolvida com o objetivo de analisar os efeitos das pistas visuais na marcha em pacientes com DP.

  15. Generalization performance of regularized neural network models

    DEFF Research Database (Denmark)

    Larsen, Jan; Hansen, Lars Kai

    1994-01-01

    Architecture optimization is a fundamental problem of neural network modeling. The optimal architecture is defined as the one which minimizes the generalization error. This paper addresses estimation of the generalization performance of regularized, complete neural network models. Regularization...

  16. EXPRESSÃO REGULAR NUMÉRICA

    Directory of Open Access Journals (Sweden)

    Bruno Vier Hoffmeister

    2014-06-01

    Full Text Available This article defines the formal definition of the computer program language Numeric Regular Expression. A language concept inspired by Regular Expression syntax, applying your power and flexibility to numeric chains are describe.

  17. Multiple graph regularized nonnegative matrix factorization

    KAUST Repository

    Wang, Jim Jing-Yan

    2013-10-01

    Non-negative matrix factorization (NMF) has been widely used as a data representation method based on components. To overcome the disadvantage of NMF in failing to consider the manifold structure of a data set, graph regularized NMF (GrNMF) has been proposed by Cai et al. by constructing an affinity graph and searching for a matrix factorization that respects graph structure. Selecting a graph model and its corresponding parameters is critical for this strategy. This process is usually carried out by cross-validation or discrete grid search, which are time consuming and prone to overfitting. In this paper, we propose a GrNMF, called MultiGrNMF, in which the intrinsic manifold is approximated by a linear combination of several graphs with different models and parameters inspired by ensemble manifold regularization. Factorization metrics and linear combination coefficients of graphs are determined simultaneously within a unified object function. They are alternately optimized in an iterative algorithm, thus resulting in a novel data representation algorithm. Extensive experiments on a protein subcellular localization task and an Alzheimer\\'s disease diagnosis task demonstrate the effectiveness of the proposed algorithm. © 2013 Elsevier Ltd. All rights reserved.

  18. Split Dimensional Regularization for the Temporal Gauge

    OpenAIRE

    Chen, Yaw-Hwang; Hsieh, Ron-Jou; Lin, Chilong

    1996-01-01

    A split dimensional regularization, which was introduced for the Coulomb gauge by Leibbrandt and Williams, is used to regularize the spurious singularities of Yang-Mills theory in the temporal gauge. Typical one-loop split dimensionally regularized temporal gauge integrals, and hence the renormalization structure of the theory are shown to be the same as those calculated with some nonprincipal-value prescriptions.

  19. Supervised scale-regularized linear convolutionary filters

    DEFF Research Database (Denmark)

    Loog, Marco; Lauze, Francois Bernard

    2017-01-01

    benefit from some form of regularization and, secondly, arguing that the problem of scale has not been taken care of in a very satis- factory manner, we come to a combined resolution of both of these shortcomings by proposing a technique that we coin scale regularization. This regularization problem can...

  20. Efeito de um programa de exercício de longa duração no controlo glicémico de indivíduos 116 portadores de Diabetes Melllitus do tipo 2

    OpenAIRE

    Magalhães, Pedro M.; Pimenta, Nuno; Duarte, José Alberto

    2016-01-01

    Os efeitos benéficos da prática regular de exercício físico na melhoria do controlo glicémico em doentes com diabetes mellitus do tipo 2 (DM2) estão relativamente bem documentados na literatura, nomeadamente em programas de curta duração (4 a 16 semanas). Menor consenso existe sobre a influência dos efeitos no longo prazo. No presente estudo, procurou-se avaliar os efeitos de um programa de exercício físico regular de longa duração no controlo glicémico e na resistência à insulina, em doen...

  1. Slimming and regularization of cozero maps

    Directory of Open Access Journals (Sweden)

    Mohamad Mehdi Ebrahimi

    2017-01-01

    Full Text Available Cozero maps are generalized forms of cozero elements. Two particular cases of cozero maps, slim and regular cozero maps, are significant. In this paper we present methods to construct slim and regular cozero maps from a given cozero map. The construction of the slim and the regular cozero map from a cozero map are called slimming and regularization of the cozero map, respectively. Also, we prove that the slimming and regularization create reflector functors, and so we may say that they are the best method of constructing slim and regular cozero maps, in the sense of category theory. Finally, we give slim regularization for a cozero map c:M→L in the general case where A is not a Q-algebra. We use the ring and module of fractions, in this construction process.

  2. Efeito de um programa de resistência muscular na capacidade funcional e na força muscular dos extensores do joelho em idosas pré-frágeis da comunidade: ensaio clínico aleatorizado do tipo crossover Impact of resistance exercise program on functional capacity and muscular strength of knee extensor in pre-frail community-dwelling older women: a randomized crossover trial

    Directory of Open Access Journals (Sweden)

    Lygia P. Lustosa

    2011-08-01

    Full Text Available CONTEXTUALIZAÇÃO: Na síndrome de fragilidade em idosos, há diminuição das reservas de energia e resistência aos estressores, com aumento da vulnerabilidade. OBJETIVO: Verificar o efeito do treinamento de força muscular com carga na capacidade funcional e força muscular dos extensores do joelho e sua associação, após treinamento, em idosas pré-frágeis da comunidade. MÉTODOS:Participaram 32 idosas, pré-frágeis, da comunidade. Excluíram-se aquelas com Miniexame do Estado Mental (MEEM incompatível; cirurgias ortopédicas dos membros inferiores; fraturas; doenças neurológicas; doenças inflamatórias agudas; neoplasias; atividade física regular; uso de medicamento com ação no sistema imunológico e sem marcha independente. Avaliou-se a capacidade funcional (Timed Up and Go - TUG e velocidade de marcha - TC10 e a força muscular dos extensores do joelho (Byodex System 3 Pro® nas velocidades angulares de 60 e 180(0/s. Para o fortalecimento muscular, utilizou-se carga de 75% de resistência máxima (1RM, durante dez semanas, três vezes/semana. A análise estatística foi feita pela ANOVA e Spearman (α=5%. RESULTADOS: Após o treinamento, houve melhora estatística do trabalho normalizado em 180(0/s (F=12,71, p=0,02, na potência, em 180(0/s (F=15,40, p=0,02 e na capacidade funcional (TUG, F=9,54, p=0,01; TC10, F=3,80, p=0,01. Houve boa correlação negativa significativa do TUG com as medidas de trabalho normalizado em 60 e 180(0/s (r=-0,65, p=0,01; r=-0,72, p=0,01. CONCLUSÃO: O treinamento produziu melhora da potência muscular e capacidade funcional. A melhora da potência associou-se à melhora funcional, importante variável para a qualidade de vida de idosas pré-frágeis. Artigo registrado no ISRCT register sob o número ISRCTN62824599.BACKGROUND: Frailty syndrome in elderly people is characterized by a reduction of energy reserves and also by a decreased of resistance to stressors, resulting in an increase of

  3. Regularities development of entrepreneurial structures in regions

    Directory of Open Access Journals (Sweden)

    Julia Semenovna Pinkovetskaya

    2012-12-01

    Full Text Available Consider regularities and tendencies for the three types of entrepreneurial structures — small enterprises, medium enterprises and individual entrepreneurs. The aim of the research was to confirm the possibilities of describing indicators of aggregate entrepreneurial structures with the use of normal law distribution functions. Presented proposed by the author the methodological approach and results of construction of the functions of the density distribution for the main indicators for the various objects: the Russian Federation, regions, as well as aggregates ofentrepreneurial structures, specialized in certain forms ofeconomic activity. All the developed functions, as shown by the logical and statistical analysis, are of high quality and well-approximate the original data. In general, the proposed methodological approach is versatile and can be used in further studies of aggregates of entrepreneurial structures. The received results can be applied in solving a wide range of problems justify the need for personnel and financial resources at the federal, regional and municipal levels, as well as the formation of plans and forecasts of development entrepreneurship and improvement of this sector of the economy.

  4. Identifying Cognitive States Using Regularity Partitions.

    Science.gov (United States)

    Pappas, Ioannis; Pardalos, Panos

    2015-01-01

    Functional Magnetic Resonance (fMRI) data can be used to depict functional connectivity of the brain. Standard techniques have been developed to construct brain networks from this data; typically nodes are considered as voxels or sets of voxels with weighted edges between them representing measures of correlation. Identifying cognitive states based on fMRI data is connected with recording voxel activity over a certain time interval. Using this information, network and machine learning techniques can be applied to discriminate the cognitive states of the subjects by exploring different features of data. In this work we wish to describe and understand the organization of brain connectivity networks under cognitive tasks. In particular, we use a regularity partitioning algorithm that finds clusters of vertices such that they all behave with each other almost like random bipartite graphs. Based on the random approximation of the graph, we calculate a lower bound on the number of triangles as well as the expectation of the distribution of the edges in each subject and state. We investigate the results by comparing them to the state of the art algorithms for exploring connectivity and we argue that during epochs that the subject is exposed to stimulus, the inspected part of the brain is organized in an efficient way that enables enhanced functionality.

  5. Identifying Cognitive States Using Regularity Partitions.

    Directory of Open Access Journals (Sweden)

    Ioannis Pappas

    Full Text Available Functional Magnetic Resonance (fMRI data can be used to depict functional connectivity of the brain. Standard techniques have been developed to construct brain networks from this data; typically nodes are considered as voxels or sets of voxels with weighted edges between them representing measures of correlation. Identifying cognitive states based on fMRI data is connected with recording voxel activity over a certain time interval. Using this information, network and machine learning techniques can be applied to discriminate the cognitive states of the subjects by exploring different features of data. In this work we wish to describe and understand the organization of brain connectivity networks under cognitive tasks. In particular, we use a regularity partitioning algorithm that finds clusters of vertices such that they all behave with each other almost like random bipartite graphs. Based on the random approximation of the graph, we calculate a lower bound on the number of triangles as well as the expectation of the distribution of the edges in each subject and state. We investigate the results by comparing them to the state of the art algorithms for exploring connectivity and we argue that during epochs that the subject is exposed to stimulus, the inspected part of the brain is organized in an efficient way that enables enhanced functionality.

  6. Regularity extraction from non-adjacent sounds.

    Science.gov (United States)

    Bendixen, Alexandra; Schröger, Erich; Ritter, Walter; Winkler, István

    2012-01-01

    The regular behavior of sound sources helps us to make sense of the auditory environment. Regular patterns may, for instance, convey information on the identity of a sound source (such as the acoustic signature of a train moving on the rails). Yet typically, this signature overlaps in time with signals emitted from other sound sources. It is generally assumed that auditory regularity extraction cannot operate upon this mixture of signals because it only finds regularities between adjacent sounds. In this view, the auditory environment would be grouped into separate entities by means of readily available acoustic cues such as separation in frequency and location. Regularity extraction processes would then operate upon the resulting groups. Our new experimental evidence challenges this view. We presented two interleaved sound sequences which overlapped in frequency range and shared all acoustic parameters. The sequences only differed in their underlying regular patterns. We inserted deviants into one of the sequences to probe whether the regularity was extracted. In the first experiment, we found that these deviants elicited the mismatch negativity (MMN) component. Thus the auditory system was able to find the regularity between the non-adjacent sounds. Regularity extraction was not influenced by sequence cohesiveness as manipulated by the relative duration of tones and silent inter-tone-intervals. In the second experiment, we showed that a regularity connecting non-adjacent sounds was discovered only when the intervening sequence also contained a regular pattern, but not when the intervening sounds were randomly varying. This suggests that separate regular patterns are available to the auditory system as a cue for identifying signals coming from distinct sound sources. Thus auditory regularity extraction is not necessarily confined to a processing stage after initial sound grouping, but may precede grouping when other acoustic cues are unavailable.

  7. An adaptive regularization parameter choice strategy for multispectral bioluminescence tomography

    Energy Technology Data Exchange (ETDEWEB)

    Feng Jinchao; Qin Chenghu; Jia Kebin; Han Dong; Liu Kai; Zhu Shouping; Yang Xin; Tian Jie [Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, P. O. Box 2728, Beijing 100190 (China); College of Electronic Information and Control Engineering, Beijing University of Technology, Beijing 100124 (China); Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, P. O. Box 2728, Beijing 100190 (China); Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, P. O. Box 2728, Beijing 100190 (China) and School of Life Sciences and Technology, Xidian University, Xi' an 710071 (China)

    2011-11-15

    Purpose: Bioluminescence tomography (BLT) provides an effective tool for monitoring physiological and pathological activities in vivo. However, the measured data in bioluminescence imaging are corrupted by noise. Therefore, regularization methods are commonly used to find a regularized solution. Nevertheless, for the quality of the reconstructed bioluminescent source obtained by regularization methods, the choice of the regularization parameters is crucial. To date, the selection of regularization parameters remains challenging. With regards to the above problems, the authors proposed a BLT reconstruction algorithm with an adaptive parameter choice rule. Methods: The proposed reconstruction algorithm uses a diffusion equation for modeling the bioluminescent photon transport. The diffusion equation is solved with a finite element method. Computed tomography (CT) images provide anatomical information regarding the geometry of the small animal and its internal organs. To reduce the ill-posedness of BLT, spectral information and the optimal permissible source region are employed. Then, the relationship between the unknown source distribution and multiview and multispectral boundary measurements is established based on the finite element method and the optimal permissible source region. Since the measured data are noisy, the BLT reconstruction is formulated as l{sub 2} data fidelity and a general regularization term. When choosing the regularization parameters for BLT, an efficient model function approach is proposed, which does not require knowledge of the noise level. This approach only requests the computation of the residual and regularized solution norm. With this knowledge, we construct the model function to approximate the objective function, and the regularization parameter is updated iteratively. Results: First, the micro-CT based mouse phantom was used for simulation verification. Simulation experiments were used to illustrate why multispectral data were used

  8. Continuous Flattening of a Regular Tetrahedron with Explicit Mappings

    Directory of Open Access Journals (Sweden)

    Jin-ichi Itoh

    2012-01-01

    Full Text Available We proved in [10] that each Platonic polyhedron P can be folded into a flat multilayered face of P by a continuous folding process of polyhedra. In this paper, we give explicit formulas of continuous functions for such a continuous flattening process in R³ for a regular tetrahedron.The article is published in the author’s wording.

  9. Regular Minimality Principle in Relation to Decision Making and Categorization

    Science.gov (United States)

    2010-10-20

    comprehensive stand-alone program which checks for Regular Minimality, computed Fechnerian distances and geodesies, and performs follow-up analyses ...restrictiveness of the notion of weak dissimilarity function and the various ways of dealing with conjoint independent classifications. The topic of

  10. Slimming and regularization of cozero maps

    Directory of Open Access Journals (Sweden)

    Mohamad Mehdi Ebrahimi

    2017-01-01

    Full Text Available Cozero maps are generalized forms of cozero elements. Two particular cases of cozero maps, slim and regular cozero maps, are significant. In this paper we present methods to construct slim and regular cozero maps from a given  cozero map. The construction of the slim and the regular cozero map from a cozero map are called slimming and regularization of the cozero map, respectively. Also, we prove that the slimming and regularization create reflector functors, and so we may say that they are the best method of constructing slim and regular cozero maps, in the sense of category theory. Finally, we give slim regularizationfor a cozero map $c:Mrightarrow L$ in the general case where $A$is not a ${Bbb Q}$-algebra. We use the ring and module offractions, in this construction process.

  11. Nonlinear regularization methods for ill-posed problems with piecewise constant or strongly varying solutions

    Science.gov (United States)

    Egger, H.; Leitão, A.

    2009-11-01

    In this paper we consider nonlinear ill-posed problems with piecewise constant or strongly varying solutions. A class of nonlinear regularization methods is proposed, in which smooth approximations to the Heavyside function are used to reparameterize functions in the solution space by an auxiliary function of levelset type. The analysis of the resulting regularization methods is carried out in two steps: first, we interpret the algorithms as nonlinear regularization methods for recovering the auxiliary function. This allows us to apply standard results from regularization theory, and we prove convergence of regularized approximations for the auxiliary function; additionally, we obtain the convergence of the regularized solutions, which are obtained from the auxiliary function by the nonlinear transformation. Second, we analyze the proposed methods as approximations to the levelset regularization method analyzed in [Frühauf F, Scherzer O and Leitão A 2005 Analysis of regularization methods for the solution of ill-posed problems involving discontinuous operators SIAM J. Numer. Anal. 43 767-86], which follows as a limit case when the smooth functions used for the nonlinear transformations converge to the Heavyside function. For illustration, we consider the application of the proposed algorithms to elliptic Cauchy problems, which are known to be severely ill-posed, and typically allow only for limited reconstructions. Our numerical examples demonstrate that the proposed methods provide accurate reconstructions of piecewise constant solutions also for these severely ill-posed benchmark problems.

  12. The regularization of Old English weak verbs

    OpenAIRE

    Marta Tío Sáenz

    2015-01-01

    [EN] This article deals with the regularization of non-standard spellings of the verbal forms extracted from a corpus. It addresses the question of what the limits of regularization are when lemmatizing Old English weak verbs. The purpose of such regularization, also known as normalization, is to carry out lexicological analysis or lexicographical work. The analysis concentrates on weak verbs from the second class and draws on the lexical database of Old English Nerthus, which has incorporate...

  13. Efeitos de um treino de atenção, memória e funções executivas na cognição de idosos saudáveis Effects of an attention, memory and executive functions training on the cognition of healthy elderly people

    Directory of Open Access Journals (Sweden)

    Tatiana Quarti Irigaray

    2012-01-01

    Full Text Available INTRODUÇÃO: Estudos mostram declínio significativo em funções cognitivas, como memória, atenção e funções executivas ao longo do processo de envelhecimento normal. OBJETIVO: Verificar os efeitos de um treino de atenção, memória e funções executivas na cognição de idosos saudáveis. MÉTODOS: 76 idosos saudáveis, divididos em grupo experimental (GE e grupo controle (GC, cada um com 38 indivíduos. O GE recebeu doze sessões de treino de atenção, memória e funções executivas. RESULTADOS: O GE no pós-teste apresentou melhor desempenho em tarefas de atenção, memória de trabalho, linguagem (inferências e escrita espontânea, praxia construcional, resolução de problemas e funções executivas. Conclusão: O treino revelou resultados significativos para uma intervenção de doze sessões, indicando que idosos saudáveis podem melhorar seu desempenho cognitivo.INTRODUCTION: Studies show there is a significant decrease in cognitive functions such as attention, memory and executive functions throughout the normal aging process. OBJECTIVE: To verify the effects of an attention, memory and executive functions training on the cognition of healthy elderly people. METHODS: 76 healthy elderly subjects were divided into experimental (EG and control groups (CG, both were composed by 38 participants each. The EG received 12 training sessions in attention, memory and executive functions. RESULTS: In the post-test, the EG presented better performance in tasks of attention, working memory, language (inferences and spontaneous writing, constructional praxia, problems solving, and executive functions. CONCLUSION: The training revealed significant results for a 12-session intervention, indicating that healthy elderly individuals may improve their cognitive functions.

  14. Iterative regularization with minimum-residual methods

    DEFF Research Database (Denmark)

    Jensen, Toke Koldborg; Hansen, Per Christian

    2006-01-01

    subspaces. We provide a combination of theory and numerical examples, and our analysis confirms the experience that MINRES and MR-II can work as general regularization methods. We also demonstrate theoretically and experimentally that the same is not true, in general, for GMRES and RRGMRES - their success......We study the regularization properties of iterative minimum-residual methods applied to discrete ill-posed problems. In these methods, the projection onto the underlying Krylov subspace acts as a regularizer, and the emphasis of this work is on the role played by the basis vectors of these Krylov...... as regularization methods is highly problem dependent....

  15. Iterative Regularization with Minimum-Residual Methods

    DEFF Research Database (Denmark)

    Jensen, Toke Koldborg; Hansen, Per Christian

    2007-01-01

    subspaces. We provide a combination of theory and numerical examples, and our analysis confirms the experience that MINRES and MR-II can work as general regularization methods. We also demonstrate theoretically and experimentally that the same is not true, in general, for GMRES and RRGMRES their success......We study the regularization properties of iterative minimum-residual methods applied to discrete ill-posed problems. In these methods, the projection onto the underlying Krylov subspace acts as a regularizer, and the emphasis of this work is on the role played by the basis vectors of these Krylov...... as regularization methods is highly problem dependent....

  16. Bit-coded regular expression parsing

    DEFF Research Database (Denmark)

    Nielsen, Lasse; Henglein, Fritz

    2011-01-01

    Regular expression parsing is the problem of producing a parse tree of a string for a given regular expression. We show that a compact bit representation of a parse tree can be produced efficiently, in time linear in the product of input string size and regular expression size, by simplifying...... the DFA-based parsing algorithm due to Dub ´e and Feeley to emit the bits of the bit representation without explicitly materializing the parse tree itself. We furthermore show that Frisch and Cardelli’s greedy regular expression parsing algorithm can be straightforwardly modified to produce bit codings...

  17. Adaptive regularization using the entire solution surface.

    Science.gov (United States)

    Wu, S; Shen, X; Geyer, C J

    2009-09-01

    Several sparseness penalties have been suggested for delivery of good predictive performance in automatic variable selection within the framework of regularization. All assume that the true model is sparse. We propose a penalty, a convex combination of the L1- and L∞-norms, that adapts to a variety of situations including sparseness and nonsparseness, grouping and nongrouping. The proposed penalty performs grouping and adaptive regularization. In addition, we introduce a novel homotopy algorithm utilizing subgradients for developing regularization solution surfaces involving multiple regularizers. This permits efficient computation and adaptive tuning. Numerical experiments are conducted using simulation. In simulated and real examples, the proposed penalty compares well against popular alternatives.

  18. Parameter optimization in the regularized kernel minimum noise fraction transformation

    DEFF Research Database (Denmark)

    Nielsen, Allan Aasbjerg; Vestergaard, Jacob Schack

    2012-01-01

    Based on the original, linear minimum noise fraction (MNF) transformation and kernel principal component analysis, a kernel version of the MNF transformation was recently introduced. Inspired by we here give a simple method for finding optimal parameters in a regularized version of kernel MNF...... analysis. We consider the model signal-to-noise ratio (SNR) as a function of the kernel parameters and the regularization parameter. In 2-4 steps of increasingly refined grid searches we find the parameters that maximize the model SNR. An example based on data from the DLR 3K camera system is given....

  19. Lifshitz anomalies, Ward identities and split dimensional regularization

    Science.gov (United States)

    Arav, Igal; Oz, Yaron; Raviv-Moshe, Avia

    2017-03-01

    We analyze the structure of the stress-energy tensor correlation functions in Lifshitz field theories and construct the corresponding anomalous Ward identities. We develop a framework for calculating the anomaly coefficients that employs a split dimensional regularization and the pole residues. We demonstrate the procedure by calculating the free scalar Lifshitz scale anomalies in 2 + 1 spacetime dimensions. We find that the analysis of the regularization dependent trivial terms requires a curved spacetime description without a foliation structure. We discuss potential ambiguities in Lifshitz scale anomaly definitions.

  20. Efeitos do Kinesio Taping no Desporto

    OpenAIRE

    Pereira, Marcelo

    2012-01-01

    Trabalho apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciado em Fisioterapia O médico japonês, Dr. Kenzo Kase criou, em 1973, o kinesio taping, uma nova aplicação de ligadura adesiva, tendo como objectivo melhorar a função da musculatura, sem limitar os movimentos, reduzir a dor, edema e os espasmos musculares. Parece ter também a capacidade de prevenir lesões no desporto, sendo por isso uma técnica comummente utilizada para este efeito....

  1. Efeitos colaterais e desacertos na terapeutica antiepiletica

    Directory of Open Access Journals (Sweden)

    Eneida Baptistete Matarazzo

    1975-12-01

    Full Text Available Relatando 6 casos de pacientes que apresentaram numerosos sintomas da esfera somática e psíquica em conseqüência de tratamento feito com diferentes drogas antiepiléticas, os autores procuraram demonstrar que o remanejamento cuidadoso da terapêutica pode evitar esses inconvenientes sem prejuízo do controle dos sintomas comiciais. Os autores acentuam a necessidade dos médicos estarem atentos para a eventualidade de surgirem efeitos colaterais durante o tratamento antiepilético e, baseados em sua experiência, sugerem algumas normas de conduta para detectar precoecmente e evitar esses inconvenientes.

  2. Efeitos dos exercícios resistidos sobre o equilíbrio e a funcionalidade de idosos saudáveis: artigo de atualização Effects of resistance training on balance and functional ability in healthy elderly: an update

    Directory of Open Access Journals (Sweden)

    Marina Lorenzi Monteiro de Araújo

    2010-09-01

    Full Text Available A diminuição da força muscular com o envelhecimento e os baixos níveis de atividade física contribuem para défices funcionais e de equilíbrio. Esta revisão sistemática teve como objetivo analisar os estudos que correlacionaram o treino resistido (TR isolado, o equilíbrio e a função de idosos saudáveis. A busca nas bases do Google Acadêmico e na BVS levou à seleção de 35 estudos controlados. O TR isolado mostrou ser relevante para a função dos idosos (90% dos estudos devido sobretudo ao ganho de força e mobilidade. Exercícios de baixa e moderada intensidade tiveram melhores resultados sobre a função de idosas, frágeis e sedentários. Em relação ao equilíbrio, apesar da inconsistência dos dados, o TR parece exercer efeitos positivos, sobretudo devido a fatores neuromusculares. Estudos com parâmetros de treino e amostra uniformes são necessários para melhor comparação dos resultados, sobretudo em idosos com padrão funcional elevado.Muscle strength decrease in aging and low physical activity levels may be an indicator of balance deficits and functional limitations. The purpose of this systematic review was to assess the effects of resistance training (RT alone on balance performance and functional capacity in healthy elderly. The search in Google Scholar and BVS led to selecting 35 controlled trials. The RT alone showed to have positive effects (90% of the studies on functional tasks in elderly, associated with increases in strength and mobility. Moderate and low-intensity exercise could produce functional capacity benefits in older women, frail and sedentary elderly. Despite the inconsistency of data, resistance training appears to exert positive effects on balance, especially through neuromuscular factors. Standardization of methodology and homogeneity of sampling may ensure greater comparability of results, especially among elderly with high physical functional level.

  3. Manifestly scale-invariant regularization and quantum effective operators

    CERN Document Server

    Ghilencea, D.M.

    2016-01-01

    Scale invariant theories are often used to address the hierarchy problem, however the regularization of their quantum corrections introduces a dimensionful coupling (dimensional regularization) or scale (Pauli-Villars, etc) which break this symmetry explicitly. We show how to avoid this problem and study the implications of a manifestly scale invariant regularization in (classical) scale invariant theories. We use a dilaton-dependent subtraction function $\\mu(\\sigma)$ which after spontaneous breaking of scale symmetry generates the usual DR subtraction scale $\\mu(\\langle\\sigma\\rangle)$. One consequence is that "evanescent" interactions generated by scale invariance of the action in $d=4-2\\epsilon$ (but vanishing in $d=4$), give rise to new, finite quantum corrections. We find a (finite) correction $\\Delta U(\\phi,\\sigma)$ to the one-loop scalar potential for $\\phi$ and $\\sigma$, beyond the Coleman-Weinberg term. $\\Delta U$ is due to an evanescent correction ($\\propto\\epsilon$) to the field-dependent masses (of...

  4. Variational regularization of 3D data experiments with Matlab

    CERN Document Server

    Montegranario, Hebert

    2014-01-01

    Variational Regularization of 3D Data provides an introduction to variational methods for data modelling and its application in computer vision. In this book, the authors identify interpolation as an inverse problem that can be solved by Tikhonov regularization. The proposed solutions are generalizations of one-dimensional splines, applicable to n-dimensional data and the central idea is that these splines can be obtained by regularization theory using a trade-off between the fidelity of the data and smoothness properties.As a foundation, the authors present a comprehensive guide to the necessary fundamentals of functional analysis and variational calculus, as well as splines. The implementation and numerical experiments are illustrated using MATLAB®. The book also includes the necessary theoretical background for approximation methods and some details of the computer implementation of the algorithms. A working knowledge of multivariable calculus and basic vector and matrix methods should serve as an adequat...

  5. Variational analysis of regular mappings theory and applications

    CERN Document Server

    Ioffe, Alexander D

    2017-01-01

    This monograph offers the first systematic account of (metric) regularity theory in variational analysis. It presents new developments alongside classical results and demonstrates the power of the theory through applications to various problems in analysis and optimization theory. The origins of metric regularity theory can be traced back to a series of fundamental ideas and results of nonlinear functional analysis and global analysis centered around problems of existence and stability of solutions of nonlinear equations. In variational analysis, regularity theory goes far beyond the classical setting and is also concerned with non-differentiable and multi-valued operators. The present volume explores all basic aspects of the theory, from the most general problems for mappings between metric spaces to those connected with fairly concrete and important classes of operators acting in Banach and finite dimensional spaces. Written by a leading expert in the field, the book covers new and powerful techniques, whic...

  6. Regularized negative correlation learning for neural network ensembles.

    Science.gov (United States)

    Chen, Huanhuan; Yao, Xin

    2009-12-01

    Negative correlation learning (NCL) is a neural network ensemble learning algorithm that introduces a correlation penalty term to the cost function of each individual network so that each neural network minimizes its mean square error (MSE) together with the correlation of the ensemble. This paper analyzes NCL and reveals that the training of NCL (when lambda = 1) corresponds to training the entire ensemble as a single learning machine that only minimizes the MSE without regularization. This analysis explains the reason why NCL is prone to overfitting the noise in the training set. This paper also demonstrates that tuning the correlation parameter lambda in NCL by cross validation cannot overcome the overfitting problem. The paper analyzes this problem and proposes the regularized negative correlation learning (RNCL) algorithm which incorporates an additional regularization term for the whole ensemble. RNCL decomposes the ensemble's training objectives, including MSE and regularization, into a set of sub-objectives, and each sub-objective is implemented by an individual neural network. In this paper, we also provide a Bayesian interpretation for RNCL and provide an automatic algorithm to optimize regularization parameters based on Bayesian inference. The RNCL formulation is applicable to any nonlinear estimator minimizing the MSE. The experiments on synthetic as well as real-world data sets demonstrate that RNCL achieves better performance than NCL, especially when the noise level is nontrivial in the data set.

  7. On the MSE Performance and Optimization of Regularized Problems

    KAUST Repository

    Alrashdi, Ayed

    2016-11-01

    The amount of data that has been measured, transmitted/received, and stored in the recent years has dramatically increased. So, today, we are in the world of big data. Fortunately, in many applications, we can take advantages of possible structures and patterns in the data to overcome the curse of dimensionality. The most well known structures include sparsity, low-rankness, block sparsity. This includes a wide range of applications such as machine learning, medical imaging, signal processing, social networks and computer vision. This also led to a specific interest in recovering signals from noisy compressed measurements (Compressed Sensing (CS) problem). Such problems are generally ill-posed unless the signal is structured. The structure can be captured by a regularizer function. This gives rise to a potential interest in regularized inverse problems, where the process of reconstructing the structured signal can be modeled as a regularized problem. This thesis particularly focuses on finding the optimal regularization parameter for such problems, such as ridge regression, LASSO, square-root LASSO and low-rank Generalized LASSO. Our goal is to optimally tune the regularizer to minimize the mean-squared error (MSE) of the solution when the noise variance or structure parameters are unknown. The analysis is based on the framework of the Convex Gaussian Min-max Theorem (CGMT) that has been used recently to precisely predict performance errors.

  8. Regularized friction and continuation: Comparison with Coulomb's law

    Science.gov (United States)

    Vigué, Pierre; Vergez, Christophe; Karkar, Sami; Cochelin, Bruno

    2017-02-01

    Periodic solutions of systems with friction are difficult to investigate because of the non-smooth nature of friction laws. This paper examines periodic solutions and most notably stick-slip, on a simple one-degree-of-freedom system (mass, spring, damper, and belt), with Coulomb's friction law, and with a regularized friction law (i.e. the friction coefficient becomes a function of relative speed, with a stiffness parameter). With Coulomb's law, the stick-slip solution is constructed step by step, which gives a usable existence condition. With the regularized law, the Asymptotic Numerical Method and the Harmonic Balance Method provide bifurcation diagrams with respect to the belt speed or normal force, and for several values of the regularization parameter. Formulations from the Coulomb case give the means of a comparison between regularized solutions and a standard reference. With an appropriate definition, regularized stick-slip motion exists, its amplitude increases with respect to the belt speed and its pulsation decreases with respect to the normal force.

  9. Efeitos da atorvastatina, fluvastatina, pravastatina e simvastatina sobre a função endotelial, a peroxidação lipídica e a aterosclerose aórtica em coelhos hipercolesterolêmicos Effects of atorvastatin, fluvastatin, pravastatin, and simvastatin on endothelial function, lipid peroxidation, and aortic atherosclerosis in hypercholesterolemic rabbits

    Directory of Open Access Journals (Sweden)

    Paulo Afonso Ribeiro Jorge

    2005-04-01

    Full Text Available OBJETIVO: Comparar os efeitos da atorvastatina, fluvastatina, pravastatina e simvastatina sobre a função endotelial, a aterosclerose aórtica e o teor de malonodialdeído (MDA nas LDL nativas, oxidadas e na parede arterial de coelhos hipercolesterolêmicos, depois que as doses destas estatinas foram ajustadas para reduzir o colesterol total plasmático a valores similares. MÉTODOS: Coelhos machos, foram separados em grupos de 10 animais (n=10, chamados hipercolesterolêmico (controle, atorvastatina, fluvastatina, pravastatina e normal. A exceção do grupo normal, os animais foram alimentados com ração padrão acrescida de colesterol a 0,5% e óleo de coco a 2% durante 45 dias. As drogas foram administradas a partir do 15º dia do início do experimento e no 30º dia, as doses foram ajustadas, através do controle do colesterol plasmático, para obter valores semelhantes em cada grupo. Ao final do experimento foi dosado o colesterol plasmático e as lipoproteinas e retirado um segmento de aorta torácica para estudo da função endotelial, da peroxidação lipídica e exame histológico para medida da aterosclerose aórtica. RESULTADOS: As estatinas reduziram significantemente o colesterol total plasmático, as LDL-colesterol e a aterosclerose aórtica. O teor de MDA também foi significantemente reduzido nas LDL nativas e oxidadas, assim como na parede arterial. O relaxamento-dependente do endotélio foi significantemente maior no grupo tratado em comparação ao hipercolesterolêmico. CONCLUSÃO: As estatinas, em doses ajustadas, tiveram efeito significante e similar em reduzir a peroxidação lipídica nas LDL e na parede arterial, na regressão da aterosclerose aórtica e na reversão da disfunção endotelial.OBJECTIVE: To compare the effects of atorvastatin, fluvastatin, pravastatin, and simvastatin on endothelial function, aortic atherosclerosis, and the content of malondialdehyde (MDA in native and oxidized LDL and in the arterial

  10. A regularized stationary mean-field game

    KAUST Repository

    Yang, Xianjin

    2016-04-19

    In the thesis, we discuss the existence and numerical approximations of solutions of a regularized mean-field game with a low-order regularization. In the first part, we prove a priori estimates and use the continuation method to obtain the existence of a solution with a positive density. Finally, we introduce the monotone flow method and solve the system numerically.

  11. Automating InDesign with Regular Expressions

    CERN Document Server

    Kahrel, Peter

    2006-01-01

    If you need to make automated changes to InDesign documents beyond what basic search and replace can handle, you need regular expressions, and a bit of scripting to make them work. This Short Cut explains both how to write regular expressions, so you can find and replace the right things, and how to use them in InDesign specifically.

  12. Regular Event Structures and Finite Petri Nets

    DEFF Research Database (Denmark)

    Nielsen, M.; Thiagarajan, P.S.

    2002-01-01

    We present the notion of regular event structures and conjecture that they correspond exactly to finite 1-safe Petri nets. We show that the conjecture holds for the conflict-free case. Even in this restricted setting, the proof is non-trivial and involves a natural subclass of regular event...

  13. On infinite regular and chiral maps

    OpenAIRE

    Arredondo, John A.; Valdez, Camilo Ramírez y Ferrán

    2015-01-01

    We prove that infinite regular and chiral maps take place on surfaces with at most one end. Moreover, we prove that an infinite regular or chiral map on an orientable surface with genus can only be realized on the Loch Ness monster, that is, the topological surface of infinite genus with one end.

  14. Effect of modified clays on the structure and functional properties of biofilms produced with zein Efeito das argilas modificadas na estrutura e propriedades funcionais de biofilmes produzidos com zeína

    Directory of Open Access Journals (Sweden)

    Luciana Lopes Tavares

    2012-06-01

    Full Text Available The purpose of this study was to evaluate changes in the structure and some functional properties of biofilms added with modified clays (Cloisite® 15A and Cloisite® 30B prepared by the casting method. The analysis of the microstructure of the films, scanning electron microscopy (SEM, Optical microscopy (MO, and Infrared Spectroscopy (FTIR indicated that the addition of clay in the films resulted in the formation of a heterogeneous microstructure, microcomposite or tactoid. Due to the formation of a microcomposite structure, functional properties of the films added with both clays such as opacity, solubility, and permeability to water vapor (PVA, were not better than those of the control film. Thus, it was concluded that although it is possible to produce a film added with modified clays using the casting method, it was not possible to obtain intercalation or exfoliation in a nanocomposite, which would result in improved functional properties.O propósito deste estudo foi avaliar mudanças na estrutura e em algumas propriedades funcionais de biofilmes de zeína adicionados de argilas modificadas (Cloisite® 15A e Cloisite® 30B elaborados pela técnica casting. Por meio do uso de técnicas de análise de microestrutura dos filmes, Microscopia Eletrônica de Varredura (MEV, Microscopia Ótica (MO e Espectroscopia no Infravermelho (FTIR, observou-se que os acréscimos de argilas resultaram na formação de uma microestrutura heterogênea, formando um microcompósito ou tactoide. Devido à formação da estrutura tipo tactoide, as propriedades funcionais de opacidade, solubilidade e permeabilidade ao vapor d'água (PVA, para os filmes adicionados de argilas, não foram melhores do que as obtidas para o filme controle. Assim, concluiu-se que é possível elaborar um filme adicionado de argilas modificadas usando a técnica casting, porém não foi possível obter intercalação ou esfoliação em nanocompósito, os quais resultariam em melhores

  15. Local regularity analysis of strata heterogeneities from sonic logs

    Directory of Open Access Journals (Sweden)

    S. Gaci

    2010-09-01

    Full Text Available Borehole logs provide geological information about the rocks crossed by the wells. Several properties of rocks can be interpreted in terms of lithology, type and quantity of the fluid filling the pores and fractures.

    Here, the logs are assumed to be nonhomogeneous Brownian motions (nhBms which are generalized fractional Brownian motions (fBms indexed by depth-dependent Hurst parameters H(z. Three techniques, the local wavelet approach (LWA, the average-local wavelet approach (ALWA, and Peltier Algorithm (PA, are suggested to estimate the Hurst functions (or the regularity profiles from the logs.

    First, two synthetic sonic logs with different parameters, shaped by the successive random additions (SRA algorithm, are used to demonstrate the potential of the proposed methods. The obtained Hurst functions are close to the theoretical Hurst functions. Besides, the transitions between the modeled layers are marked by Hurst values discontinuities. It is also shown that PA leads to the best Hurst value estimations.

    Second, we investigate the multifractional property of sonic logs data recorded at two scientific deep boreholes: the pilot hole VB and the ultra deep main hole HB, drilled for the German Continental Deep Drilling Program (KTB. All the regularity profiles independently obtained for the logs provide a clear correlation with lithology, and from each regularity profile, we derive a similar segmentation in terms of lithological units. The lithological discontinuities (strata' bounds and faults contacts are located at the local extrema of the Hurst functions. Moreover, the regularity profiles are compared with the KTB estimated porosity logs, showing a significant relation between the local extrema of the Hurst functions and the fluid-filled fractures. The Hurst function may then constitute a tool to characterize underground heterogeneities.

  16. Local regularity analysis of strata heterogeneities from sonic logs

    Science.gov (United States)

    Gaci, S.; Zaourar, N.; Hamoudi, M.; Holschneider, M.

    2010-09-01

    Borehole logs provide geological information about the rocks crossed by the wells. Several properties of rocks can be interpreted in terms of lithology, type and quantity of the fluid filling the pores and fractures. Here, the logs are assumed to be nonhomogeneous Brownian motions (nhBms) which are generalized fractional Brownian motions (fBms) indexed by depth-dependent Hurst parameters H(z). Three techniques, the local wavelet approach (LWA), the average-local wavelet approach (ALWA), and Peltier Algorithm (PA), are suggested to estimate the Hurst functions (or the regularity profiles) from the logs. First, two synthetic sonic logs with different parameters, shaped by the successive random additions (SRA) algorithm, are used to demonstrate the potential of the proposed methods. The obtained Hurst functions are close to the theoretical Hurst functions. Besides, the transitions between the modeled layers are marked by Hurst values discontinuities. It is also shown that PA leads to the best Hurst value estimations. Second, we investigate the multifractional property of sonic logs data recorded at two scientific deep boreholes: the pilot hole VB and the ultra deep main hole HB, drilled for the German Continental Deep Drilling Program (KTB). All the regularity profiles independently obtained for the logs provide a clear correlation with lithology, and from each regularity profile, we derive a similar segmentation in terms of lithological units. The lithological discontinuities (strata' bounds and faults contacts) are located at the local extrema of the Hurst functions. Moreover, the regularity profiles are compared with the KTB estimated porosity logs, showing a significant relation between the local extrema of the Hurst functions and the fluid-filled fractures. The Hurst function may then constitute a tool to characterize underground heterogeneities.

  17. Regularization Techniques for Linear Least-Squares Problems

    KAUST Repository

    Suliman, Mohamed

    2016-04-01

    Linear estimation is a fundamental branch of signal processing that deals with estimating the values of parameters from a corrupted measured data. Throughout the years, several optimization criteria have been used to achieve this task. The most astonishing attempt among theses is the linear least-squares. Although this criterion enjoyed a wide popularity in many areas due to its attractive properties, it appeared to suffer from some shortcomings. Alternative optimization criteria, as a result, have been proposed. These new criteria allowed, in one way or another, the incorporation of further prior information to the desired problem. Among theses alternative criteria is the regularized least-squares (RLS). In this thesis, we propose two new algorithms to find the regularization parameter for linear least-squares problems. In the constrained perturbation regularization algorithm (COPRA) for random matrices and COPRA for linear discrete ill-posed problems, an artificial perturbation matrix with a bounded norm is forced into the model matrix. This perturbation is introduced to enhance the singular value structure of the matrix. As a result, the new modified model is expected to provide a better stabilize substantial solution when used to estimate the original signal through minimizing the worst-case residual error function. Unlike many other regularization algorithms that go in search of minimizing the estimated data error, the two new proposed algorithms are developed mainly to select the artifcial perturbation bound and the regularization parameter in a way that approximately minimizes the mean-squared error (MSE) between the original signal and its estimate under various conditions. The first proposed COPRA method is developed mainly to estimate the regularization parameter when the measurement matrix is complex Gaussian, with centered unit variance (standard), and independent and identically distributed (i.i.d.) entries. Furthermore, the second proposed COPRA

  18. The effects of knee extensor eccentric training on functional tests in healthy subjects Os efeitos do treino isocinético excêntrico dos extensores do joelho nos testes funcionais em sujeitos saudáveis

    Directory of Open Access Journals (Sweden)

    Heleodório H. Santos

    2010-08-01

    Full Text Available BACKGROUND: It is well known that eccentric training increases muscle strength and promotes greater neural activation, and therefore has been used in the recovery of knee extensors. The hypothesis of this study was that there would be a strong correlation between knee extensor torque and functional tests. OBJECTIVES: To investigate the relationship between knee extensor peak torque and functional tests of agility (runs and propulsion (hop for distance after short-term isokinetic eccentric training. METHODS: Twenty healthy and active male undergraduate students (age 22.5±2.1 years; height 1.72±0.10 m; weight 67.8±9.5 kg; body mass index: 22.5±2.0 kg/m², with no abnormalities or history of injury of the limbs, performed an isokinetic assessment of the knee extensors and flexors and also functional tests before and after isokinetic training, which consisted of 3 sets of 10 MVECs at 30º/s, with 3 minutes of rest between sets, twice a week for 6 weeks. RESULTS: The eccentric training increased the extensor peak torque (16, 27 and 17%; PCONTEXTUALIZAÇÃO: Sabe-se que o treino excêntrico aumenta a força muscular, promovendo uma maior ativação neural e, portanto, tem sido usado na recuperação do torque extensor. A hipótese deste estudo foi a de que possa existir uma forte correlação entre o torque extensor do joelho e os testes funcionais. OBJETIVOS: Correlacionar o torque extensor do joelho com os testes funcionais de agilidade (corridas e impulsão (saltos em distância após o treino isocinético excêntrico de curta duração. MÉTODOS: Vinte homens universitários, ativos e saudáveis (22,5±2,1 anos; 1,72±0,10 m; 67,8±9,5 kg; IMC 22,5±2,0 kg/m², sem reportar anormalidades ou história de lesão no membro inferior, realizaram avaliação isocinética do torque extensor e flexor do joelho e testes funcionais antes e depois do treino isocinético que consistiu em três séries de 10 CEVM a 30º/s, com 3 minutos de repouso entre as

  19. Completeness and regularity of generalized fuzzy graphs.

    Science.gov (United States)

    Samanta, Sovan; Sarkar, Biswajit; Shin, Dongmin; Pal, Madhumangal

    2016-01-01

    Fuzzy graphs are the backbone of many real systems like networks, image, scheduling, etc. But, due to some restriction on edges, fuzzy graphs are limited to represent for some systems. Generalized fuzzy graphs are appropriate to avoid such restrictions. In this study generalized fuzzy graphs are introduced. In this study, matrix representation of generalized fuzzy graphs is described. Completeness and regularity are two important parameters of graph theory. Here, regular and complete generalized fuzzy graphs are introduced. Some properties of them are discussed. After that, effective regular graphs are exemplified.

  20. J-regular rings with injectivities

    OpenAIRE

    Shen, Liang

    2010-01-01

    A ring $R$ is called a J-regular ring if R/J(R) is von Neumann regular, where J(R) is the Jacobson radical of R. It is proved that if R is J-regular, then (i) R is right n-injective if and only if every homomorphism from an $n$-generated small right ideal of $R$ to $R_{R}$ can be extended to one from $R_{R}$ to $R_{R}$; (ii) R is right FP-injective if and only if R is right (J, R)-FP-injective. Some known results are improved.

  1. Effect of regular exercise on senile dementia patients.

    Science.gov (United States)

    Kwak, Y-S; Um, S-Y; Son, T-G; Kim, D-J

    2008-06-01

    Dementia population worldwide is considerable in elderly people. Exercise regulates the brain function, but the mechanism by which it does so is unknown. The effect of regular exercise on cognitive function and exercise capacity in senile dementia patients was investigated. Thirty female patients with senile dementia who participated in the study were divided into two groups: the exercise group (EG, n = 15) and the control group (CG, n = 15). The exercise group completed a regular exercise program, and their cognitive function, activities of daily living and exercise capacity levels were evaluated at baseline, 6 months and after 12 months. Subjects exercised 30 - 60 minutes per day, 2 - 3 times per week for 12 months. Mini-mental state examination (MMSE) (pre: 14.53 +/- 5.34, post: 17.47 +/- 6.90) and ADL (pre: 14.40 +/- 5.32, post: 17.53 +/- 5.46) scores were significantly enhanced in the exercise group with senile dementia, compared to those in the control group. Exercise capacities such as cardiopulmonary function (pre: 128.47 +/- 55.43, post: 184.40 +/- 41.16), muscle strength (pre: 10.07 +/- 3.61, post: 13.7 +/- 3.90), muscular endurance (pre: 8.13 +/- 4.45, post: 12.13 +/- 5.14), flexibility (- 1.53 +/- .30, post: 2.20 +/- .70, balance (pre: 1.73 +/- .28, post: 1.20 +/- .77), and agility (pre: 21.80 +/- 3.24, post: 10.87 +/- 2.99) also increased in the exercise group. Our findings showed that regular exercise can enhance cognitive and functional activity scores in dementia patients, suggesting that senile dementia may improve by participating in a regular exercise program.

  2. Lattice-Valued Convergence Spaces: Weaker Regularity and p-Regularity

    Directory of Open Access Journals (Sweden)

    Lingqiang Li

    2014-01-01

    Full Text Available By using some lattice-valued Kowalsky’s dual diagonal conditions, some weaker regularities for Jäger’s generalized stratified L-convergence spaces and those for Boustique et al’s stratified L-convergence spaces are defined and studied. Here, the lattice L is a complete Heyting algebra. Some characterizations and properties of weaker regularities are presented. For Jäger’s generalized stratified L-convergence spaces, a notion of closures of stratified L-filters is introduced and then a new p-regularity is defined. At last, the relationships between p-regularities and weaker regularities are established.

  3. O Efeito Foucault: Desnaturalizando Verdades, Superando Dicotomias

    Directory of Open Access Journals (Sweden)

    Coimbra Cecilia Maria Bouças

    2001-01-01

    Full Text Available Este artigo parte de idéias contidas em algumas obras de Foucault, levantando questões referentes à produção de verdades, a hegemonia da ciência positiva e aos binarismos presentes no mundo contemporâneo. Aponta, ainda, como o pensamento desse filósofo tem sido uma potente ferramenta, que tem possibilitado colocar em análise as crenças produzidas pelo pensamento platônico, ainda hoje dominante no Ocidente. A partir daí, coloca em discussão a divisão psicologia versus política, procurando pensar que efeitos têm sido produzidos por tal dicotomia cotidiana.

  4. Efeito Kerr eletro-optico em liquidos

    OpenAIRE

    Jose Montanha Neto

    1991-01-01

    Resumo: Foi construído um sistema para o estudo do efeito Kerr eletro-óptico em líquidos, para o qual desenvolvemos um gerador de pulsos retangulares de alta tensão e curta duração, além de uma célula de Kerr com baixa birrefringência residual. Uma técnica de sinal nulo foi empregada na medida da birrefringência induzida. As constantes de Kerr de sete líquidos puros; água, acetona, clorofórmio, nitrometano, quinolina, ácido acético e isopropil benzeno (cumeno) foram medidas. Para os quatro úl...

  5. Mixed-norm regularization for brain decoding.

    Science.gov (United States)

    Flamary, R; Jrad, N; Phlypo, R; Congedo, M; Rakotomamonjy, A

    2014-01-01

    This work investigates the use of mixed-norm regularization for sensor selection in event-related potential (ERP) based brain-computer interfaces (BCI). The classification problem is cast as a discriminative optimization framework where sensor selection is induced through the use of mixed-norms. This framework is extended to the multitask learning situation where several similar classification tasks related to different subjects are learned simultaneously. In this case, multitask learning helps in leveraging data scarcity issue yielding to more robust classifiers. For this purpose, we have introduced a regularizer that induces both sensor selection and classifier similarities. The different regularization approaches are compared on three ERP datasets showing the interest of mixed-norm regularization in terms of sensor selection. The multitask approaches are evaluated when a small number of learning examples are available yielding to significant performance improvements especially for subjects performing poorly.

  6. The regularization of Old English weak verbs

    Directory of Open Access Journals (Sweden)

    Marta Tío Sáenz

    2015-07-01

    Full Text Available This article deals with the regularization of non-standard spellings of the verbal forms extracted from a corpus. It addresses the question of what the limits of regularization are when lemmatizing Old English weak verbs. The purpose of such regularization, also known as normalization, is to carry out lexicological analysis or lexicographical work. The analysis concentrates on weak verbs from the second class and draws on the lexical database of Old English Nerthus, which has incorporated the texts of the Dictionary of Old English Corpus. As regards the question of the limits of normalization, the solution adopted are, in the first place, that when it is necessary to regularize, normalization is restricted to correspondences based on dialectal and diachronic variation and, secondly, that normalization has to be unidirectional.

  7. Mixed-Norm Regularization for Brain Decoding

    Directory of Open Access Journals (Sweden)

    R. Flamary

    2014-01-01

    Full Text Available This work investigates the use of mixed-norm regularization for sensor selection in event-related potential (ERP based brain-computer interfaces (BCI. The classification problem is cast as a discriminative optimization framework where sensor selection is induced through the use of mixed-norms. This framework is extended to the multitask learning situation where several similar classification tasks related to different subjects are learned simultaneously. In this case, multitask learning helps in leveraging data scarcity issue yielding to more robust classifiers. For this purpose, we have introduced a regularizer that induces both sensor selection and classifier similarities. The different regularization approaches are compared on three ERP datasets showing the interest of mixed-norm regularization in terms of sensor selection. The multitask approaches are evaluated when a small number of learning examples are available yielding to significant performance improvements especially for subjects performing poorly.

  8. On Comparison of Adaptive Regularization Methods

    DEFF Research Database (Denmark)

    Sigurdsson, Sigurdur; Larsen, Jan; Hansen, Lars Kai

    2000-01-01

    at the expense of introducing extra bias. The overall objective of adaptive regularization is to tune the amount of regularization ensuring minimal generalization error. Regularization is a supplement to direct model selection techniques like step-wise selection and one would prefer a hybrid scheme; however...... different criteria, e.g., the Bayesian evidence. The evidence expresses basically the probability of the model, which is conceptually different from generalization error; however, asymptotically for large training data sets they will converge. First the basic model definition, training and generalization......Modeling with flexible models, such as neural networks, requires careful control of the model complexity and generalization ability of the resulting model which finds expression in the ubiquitous bias-variance dilemma. Regularization is a tool for optimizing the model structure reducing variance...

  9. Efeitos de dejeto de suínos na forma líquida e de composto orgânico na atividade do metribuzin Metribuzin soil bioactivity as a function of swine liquid manure and organic matter

    Directory of Open Access Journals (Sweden)

    Silvério de P. Freitas

    1999-04-01

    Full Text Available Este trabalho objetivou avaliar a atividade do metribuzin em função da adição de doses de dejeto de suínos na forma líquida e de composto orgânico. Foram conduzidos dez experimentos utilizando delineamento experimental inteiramente casualizado, com quatro repetições, em condições de casa-de-vegetação do Departamento de Fitotecnia da UFV. Foram avaliados cinco substratos: areia lavada, solo Podzólico Vermelho-Amarelo argilo arenoso, da região de Ponte Nova-MG misturado com doses correspondentes a 0, 20, 40 e 60 m3 ha-1 de dejeto líquido e 0, 30, 60 e 90 t ha-1 de composto orgânico associados a 10 doses de metribuzin. A aplicação do metribuzin foi feita com pulverizador costal pressurizado a CO2, após a semeadura de cinco sementes/vaso da planta indicadora (Cucumis sativus L. híbrido caipira AG.221. A irrigação dos vasos foi realizada, três vezes ao dia, por meio de simulador de chuvas, mantendo-se a umidade dos substratos em aproximadamente 80% da capacidade de campo. Aos 14 dias após a aplicação dos tratamentos foi realizada a colheita dos experimentos, seguida pela determinação da biomassa fresca da parte aérea da planta indicadora. As concentrações dos herbicidas, que resultaram em 50% de inibição do crescimento da planta teste (I50, foram calculadas a partir de equações ajustadas por meio de análise de regressão. A adsorção do metribuzin aumentou linearmente com adição de dejeto líquido ou composto orgânico ao solo, sendo que a maior adsorção ocorreu com a adição do composto orgânico. Para a maior dose de dejeto líquido (60 m3 ha-1, a relação de adsorção foi 4,79 e o aumento na adsorção em relação ao solo foi 28,01%. Entretanto, com a adição da maior dose do composto orgânico (90 t ha-1, a relação de adsorção foi 6,63 e o aumento na adsorção 32,51%.The objective of this work was to evaluate metribuzin bioactivity as a function of adding swine liquid manure doses and organic

  10. Fast and compact regular expression matching

    DEFF Research Database (Denmark)

    Bille, Philip; Farach-Colton, Martin

    2008-01-01

    We study 4 problems in string matching, namely, regular expression matching, approximate regular expression matching, string edit distance, and subsequence indexing, on a standard word RAM model of computation that allows logarithmic-sized words to be manipulated in constant time. We show how to ...... to improve the space and/or remove a dependency on the alphabet size for each problem using either an improved tabulation technique of an existing algorithm or by combining known algorithms in a new way....

  11. Regularity of Tor for weakly stable ideals

    Directory of Open Access Journals (Sweden)

    Katie Ansaldi

    2015-05-01

    Full Text Available It is proved that if I and J are weakly stable ideals in a polynomial ring R = k[x_1, . . ., x_n], with k a field, then the regularity of Tor^R_i (R/I, R/J has the expected upper bound. We also give a bound for the regularity of Ext^i_R (R/I, R for I a weakly stable ideal.

  12. Deterministic automata for extended regular expressions

    Directory of Open Access Journals (Sweden)

    Syzdykov Mirzakhmet

    2017-12-01

    Full Text Available In this work we present the algorithms to produce deterministic finite automaton (DFA for extended operators in regular expressions like intersection, subtraction and complement. The method like “overriding” of the source NFA(NFA not defined with subset construction rules is used. The past work described only the algorithm for AND-operator (or intersection of regular languages; in this paper the construction for the MINUS-operator (and complement is shown.

  13. The effect of functional limitations and fatigue on the quality of life in people with multiple sclerosis O efeito das limitações funcionais e da fadiga na qualidade de vida de indivíduos com esclerose múltipla

    Directory of Open Access Journals (Sweden)

    Leandro Alberto Calazans Nogueira

    2009-09-01

    Full Text Available The purpose of this study was to determine the effect of functional limitations and fatigue on the quality of life (QoL in people with multiple sclerosis (MS. A descriptive case series study at Lagoa Hospital - Rio de Janeiro, Brazil was carried. The main outcome measurements were demographic variables, QoL (SF-36 v.1, disability (EDSS, motor function of the upper limb (Box & Blocks test, Tone (Modified Ashworth Scale, gait (Hauser ambulatory index and fatigue (Fatigue Severity Scale. Sixty one patients fulfilled the study criteria. The mean age of patients was 39 years and 74% of patients were female. The most of cases presented mild disability (EDSSO objetivo do estudo foi determinar o efeito das limitações funcionais e da fadiga na qualidade de vida (qv de indivíduos com esclerose múltipla (em. foi conduzido um estudo descritivo de série de casos no Hospital da Lagoa - Rio de Janeiro, Brasil. As principais medidas utilizadas foram as variáveis demográficas, QV (SF-36 v.1, incapacidade (EDSS, função motora da extremidade superior (Teste da Caixa e Blocos, Tônus (Escala Modificada de Ashworth, marcha (Índice Ambulatorial de Hauser e fadiga (Escala de Severidade de Fadiga. Sessenta e um pacientes preencheram os critérios do estudo. A média de idade foi de 39 anos e 74% dos pacientes eram do gênero feminino. A maioria dos casos apresentou incapacidade leve (EDSS<3,5. Foi encontrada uma diminuição em todas dimensões da QV. Foi observada uma associação entre a função física e as variáveis EDSS, fadiga, tônus dos membros inferiores e marcha. Marcha, incapacidade, hipertonia dos membros inferiores e fadiga afetam negativamente a QV de indivíduos com EM.

  14. (2+1-dimensional regular black holes with nonlinear electrodynamics sources

    Directory of Open Access Journals (Sweden)

    Yun He

    2017-11-01

    Full Text Available On the basis of two requirements: the avoidance of the curvature singularity and the Maxwell theory as the weak field limit of the nonlinear electrodynamics, we find two restricted conditions on the metric function of (2+1-dimensional regular black hole in general relativity coupled with nonlinear electrodynamics sources. By the use of the two conditions, we obtain a general approach to construct (2+1-dimensional regular black holes. In this manner, we construct four (2+1-dimensional regular black holes as examples. We also study the thermodynamic properties of the regular black holes and verify the first law of black hole thermodynamics.

  15. EFEITO DE UM PROGRAMA DE EXERCÍCIO DE LONGA DURAÇÃO NO CONTROLO GLICÉMICO DE INDIVÍDUOS PORTADORES DE DIABETES MELLITUS DO TIPO 2

    OpenAIRE

    Magalhães, Pedro; Pimenta, Nuno; Duarte, José

    2016-01-01

    Os efeitos benéficos de programas de exercício de curta duração (4 a 16 semanas) no controlo glicémico de doentes com diabetes mellitus do tipo 2 (DM2) estão bem documentados na literatura. Menor consenso existe sobre os efeitos no longo prazo. No presente estudo, procurou-se avaliar os efeitos de um programa de exercício regular de longa duração no controlo glicémico e na resistência à insulina, em doentes com DM2. A amostra foi constituída por um grupo de referência (GR) (n=102) e um grupo ...

  16. Efeito de um programa de fisioterapia funcional em crianças com paralisia cerebral associado a orientações aos cuidadores: estudo preliminar Effect of a functional physical therapy program on cerebral palsy children, associated to guidance for their caregivers: a preliminary study

    Directory of Open Access Journals (Sweden)

    Ana Carolina Gama e Silva Brianeze

    2009-03-01

    Full Text Available O objetivo foi verificar o efeito de um programa de fisioterapia funcional para crianças com paralisia cerebral, associado a orientações aos pais e/ou cuidadores; e verificar a correlação entre as habilidades funcionais e a assistência do cuidador, utilizando o Inventário de Avaliação Pediátrica de Incapacidade (PEDI. Participaram quatro crianças entre 24 e 43 meses de idade, hemiplégicas, espásticas e nível I no sistema de classificação da função motora ampla (GMFCS. Foram realizadas quatro avaliações - uma antes do início do programa, as demais aos 30, 60 e 90 dias após a primeira -, empregando-se as partes I (Habilidades funcionais e II (Assistência do cuidador do PEDI. As crianças foram submetidas a sessões de uma hora de fisioterapia funcional três vezes por semana, durante três meses: duas vezes a sessão era de fisioterapia com base no conceito neuroevolutivo Bobath e uma vez, treino de atividades da vida diária. Também foram dadas orientações por escrito aos pais e/ou cuidadores quanto à assistência à criança, incentivando-os a praticá-la em casa. A análise dos resultados mostrou que, na última avaliação, as crianças obtiveram escores significativamente maiores que na primeira. Foi verificada correlação altamente significativa (r=1,0; p=0,083 entre as partes I e II. O programa de fisioterapia funcional associado às orientações aos pais e/ou cuidadores foi efetivo em melhorar o desempenho funcional de crianças nível I com hemiplegia espástica.The purpose was to verify the effect of a functional physical therapy program on children with cerebral palsy, associated to guidance to parents and/or caregivers; and to search for correlations between the child's functional abilities and caregivers' assistance, by means of the Pediatric Evaluation Disability Inventory (PEDI. Four hemiplegic, spastic children between 24 and 43 months old, classified at the Gross Motor Function Classification System

  17. Conservative regularization of ideal hydrodynamics and magnetohydrodynamics

    Science.gov (United States)

    Thyagaraja, A.

    2010-03-01

    Inviscid, incompressible hydrodynamics and incompressible ideal magnetohydrodynamics (MHD) share many properties such as time-reversal invariance of equations, conservation laws, and certain topological features. In three dimensions, these systems may lead to singular solutions (involving vortex and current sheets). While dissipative (viscoresistive) effects can regularize the equations leading to bounded solutions to the initial-boundary value (Cauchy) problem which presumably exist uniquely, the time-reversal symmetry and associated conservation properties are certainly destroyed. The present work is analogous to (and suggested by) the Korteweg-de Vries regularization of the one-dimensional, nonlinear kinematic wave equation. Thus the regularizations applied to the original equations of hydrodynamics and ideal MHD retain conservation properties and the symmetries of the original equations. Integral invariants which generalize those known for the original systems are shown to imply bounded enstrophy. The regularization developed can also be applied to the corresponding dissipative models (such as the Navier-Stokes equations and the viscoresistive MHD equations) and may imply interesting regularity properties for the solutions of the latter as well. The models developed thus have intrinsic mathematical interest as well as possible applications to large-scale numerical simulations in systems where dissipative effects are extremely small or even absent.

  18. Regularities, Natural Patterns and Laws of Nature

    Directory of Open Access Journals (Sweden)

    Stathis Psillos

    2014-02-01

    Full Text Available  The goal of this paper is to sketch an empiricist metaphysics of laws of nature. The key idea is that there are regularities without regularity-enforcers. Differently put, there are natural laws without law-makers of a distinct metaphysical kind. This sketch will rely on the concept of a natural pattern and more significantly on the existence of a network of natural patterns in nature. The relation between a regularity and a pattern will be analysed in terms of mereology.  Here is the road map. In section 2, I will briefly discuss the relation between empiricism and metaphysics, aiming to show that an empiricist metaphysics is possible. In section 3, I will offer arguments against stronger metaphysical views of laws. Then, in section 4 I will motivate nomic objectivism. In section 5, I will address the question ‘what is a regularity?’ and will develop a novel answer to it, based on the notion of a natural pattern. In section 6, I will raise the question: ‘what is a law of nature?’, the answer to which will be: a law of nature is a regularity that is characterised by the unity of a natural pattern.

  19. Novel Harmonic Regularization Approach for Variable Selection in Cox’s Proportional Hazards Model

    Directory of Open Access Journals (Sweden)

    Ge-Jin Chu

    2014-01-01

    Full Text Available Variable selection is an important issue in regression and a number of variable selection methods have been proposed involving nonconvex penalty functions. In this paper, we investigate a novel harmonic regularization method, which can approximate nonconvex Lq  (1/2regularizations, to select key risk factors in the Cox’s proportional hazards model using microarray gene expression data. The harmonic regularization method can be efficiently solved using our proposed direct path seeking approach, which can produce solutions that closely approximate those for the convex loss function and the nonconvex regularization. Simulation results based on the artificial datasets and four real microarray gene expression datasets, such as real diffuse large B-cell lymphoma (DCBCL, the lung cancer, and the AML datasets, show that the harmonic regularization method can be more accurate for variable selection than existing Lasso series methods.

  20. Low-Complexity Regularization Algorithms for Image Deblurring

    KAUST Repository

    Alanazi, Abdulrahman

    2016-11-01

    Image restoration problems deal with images in which information has been degraded by blur or noise. In practice, the blur is usually caused by atmospheric turbulence, motion, camera shake, and several other mechanical or physical processes. In this study, we present two regularization algorithms for the image deblurring problem. We first present a new method based on solving a regularized least-squares (RLS) problem. This method is proposed to find a near-optimal value of the regularization parameter in the RLS problems. Experimental results on the non-blind image deblurring problem are presented. In all experiments, comparisons are made with three benchmark methods. The results demonstrate that the proposed method clearly outperforms the other methods in terms of both the output PSNR and structural similarity, as well as the visual quality of the deblurred images. To reduce the complexity of the proposed algorithm, we propose a technique based on the bootstrap method to estimate the regularization parameter in low and high-resolution images. Numerical results show that the proposed technique can effectively reduce the computational complexity of the proposed algorithms. In addition, for some cases where the point spread function (PSF) is separable, we propose using a Kronecker product so as to reduce the computations. Furthermore, in the case where the image is smooth, it is always desirable to replace the regularization term in the RLS problems by a total variation term. Therefore, we propose a novel method for adaptively selecting the regularization parameter in a so-called square root regularized total variation (SRTV). Experimental results demonstrate that our proposed method outperforms the other benchmark methods when applied to smooth images in terms of PSNR, SSIM and the restored image quality. In this thesis, we focus on the non-blind image deblurring problem, where the blur kernel is assumed to be known. However, we developed algorithms that also work

  1. Efeitos da efedrina sobre as funções cardiovascular e renal de cães sob anestesia com pentobarbital sódico Efectos de la efedrina sobre las funciones cardiovascular y renal de perros bajo anestesia con pentobarbital sódico Effects of rphedrine on cardiovascular and renal function of dogs anesthetized with sodium pentobarbital

    Directory of Open Access Journals (Sweden)

    Rosa Beatriz Amorim

    2002-07-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Com a perspectiva criada por algumas pesquisas de ações diferenciadas da efedrina sobre a função renal, dependendo da dose utilizada, e considerando-se as controvérsias ainda existentes a respeito dos seus efeitos sobre a função renal, esta pesquisa experimental tem como objetivo verificar se doses diferentes de efedrina determinam efeitos hemodinâmicos e renais diferenciados. MÉTODO: Em 32 cães anestesiados com pentobarbital sódico (PS, submetidos a preparação cirúrgica, cateterismo, monitorização, expansão do volume do fluido extracelular e respiração controlada, foi estudada a hemodinâmica cardiovascular e renal e a função renal. Os cães foram distribuídos aleatoriamente em quatro grupos: G controle (n = 8, com os cães permanecendo apenas sob o efeito do PS, G ef. 2 µg (n = 8, G ef. 10 µg (n = 8 e G ef. 100 µg (n = 8, com os cães recebendo efedrina nas doses respectivas de 2, 10 e 100 µg.kg-1.min-1. Os atributos cardiovasculares e renais foram estudados em 5 momentos: controle (M1 e M2, durante a infusão de efedrina (M3 e M4 e após a suspensão da infusão de efedrina (M5. RESULTADOS: Não houve diferença significante entre os grupos em relação aos atributos estudados. Em G ef. 2 µg houve aumento significante de freqüência cardíaca, fluxo sangüíneo aórtico, débito urinário e excreção fracionária de sódio. Em G ef. 10 µg houve aumento apenas da freqüência cardíaca e fração de filtração, enquanto em G ef. 100 µg ocorreu aumento de freqüência cardíaca, pressão arterial média, pressão venosa central, fluxo sangüíneo aórtico e hematócrito; por outro lado, ocorreu diminuição dos fluxos plasmático e sangüíneo renais e aumento da resistência vascular renal. CONCLUSÕES: A efedrina, dependendo da dose utilizada, apresenta ações hemodinâmicas e renais diferenciadas.JUSTIFICATIVA Y OBJETIVOS: Con la perspectiva creada por algunas pesquisas de acciones

  2. Stream Processing Using Grammars and Regular Expressions

    DEFF Research Database (Denmark)

    Rasmussen, Ulrik Terp

    In this dissertation we study regular expression based parsing and the use of grammatical specifications for the synthesis of fast, streaming string-processing programs. In the first part we develop two linear-time algorithms for regular expression based parsing with Perl-style greedy...... disambiguation. The first algorithm operates in two passes in a semi-streaming fashion, using a constant amount of working memory and an auxiliary tape storage which is written in the first pass and consumed by the second. The second algorithm is a single-pass and optimally streaming algorithm which outputs...... as much of the parse tree as is semantically possible based on the input prefix read so far, and resorts to buffering as many symbols as is required to resolve the next choice. Optimality is obtained by performing a PSPACE-complete pre-analysis on the regular expression. In the second part we present...

  3. Surface counterterms and regularized holographic complexity

    Science.gov (United States)

    Yang, Run-Qiu; Niu, Chao; Kim, Keun-Young

    2017-09-01

    The holographic complexity is UV divergent. As a finite complexity, we propose a "regularized complexity" by employing a similar method to the holographic renor-malization. We add codimension-two boundary counterterms which do not contain any boundary stress tensor information. It means that we subtract only non-dynamic back-ground and all the dynamic information of holographic complexity is contained in the regularized part. After showing the general counterterms for both CA and CV conjectures in holographic spacetime dimension 5 and less, we give concrete examples: the BTZ black holes and the four and five dimensional Schwarzschild AdS black holes. We propose how to obtain the counterterms in higher spacetime dimensions and show explicit formulas only for some special cases with enough symmetries. We also compute the complexity of formation by using the regularized complexity.

  4. REX XML shallow parsing with regular expressions

    CERN Document Server

    Cameron, R D

    1999-01-01

    The syntax of XML is simple enough that it is possible to parse an XML document into a list of its markup and text items using a single regular expression. Such a shallow parse of an XML document can be very useful for the construction of a variety of lightweight XML processing tools. However, complex regular expressions can be difficult to construct and even more difficult to read. Using a form of literate programming for regular expressions, this paper documents a set of XML shallow parsing expressions that can be used a basis for simple, correct, efficient, robust and language-independent XML shallow parsing. Complete shallow parser implementations of less than 50 lines each in Perl, JavaScript and Lex/Flex are also given. (0 refs).

  5. Contour Propagation With Riemannian Elasticity Regularization

    DEFF Research Database (Denmark)

    Bjerre, Troels; Hansen, Mads Fogtmann; Sapru, W.

    2011-01-01

    guided corrections. This study compares manual delineations in replanning CT scans of head-and-neck patients to automatic contour propagation using deformable registration with Riemannian regularization. The potential benefit of locally assigned regularization parameters according to tissue type...... is investigated. Materials/Methods: Planning PET-CT scans plus 2 - 4 subsequent replanning CTs for five head-and-neck cancer patients were obtained. The Gross Tumor Volume (GTV) was manually delineated on the planning CT by an experienced clinician and manually propagated by pasting the set of contours from...... the planning CT onto the rescans and correcting to reflect actual anatomical changes. For deformable registration, a free-form, multi-level, B-spline deformation model with Riemannian elasticity, penalizing non-rigid local deformations, and volumetric changes, was used. Regularization parameters was defined...

  6. Generalized inverse beamforming with optimized regularization strategy

    Science.gov (United States)

    Zavala, P. A. G.; De Roeck, W.; Janssens, K.; Arruda, J. R. F.; Sas, P.; Desmet, W.

    2011-04-01

    A promising recent development on acoustic source localization and source strength estimation is the generalized inverse beamforming, which is based on the microphone array cross-spectral matrix eigenstructure. This method presents several advantages over the conventional beamforming, including a higher accuracy on the source center localization and strength estimation even with distributed coherent sources. This paper aims to improve the strength estimation of the generalized inverse beamforming method with an automated regularization factor definition. Also in this work, a virtual target grid is introduced, and source mapping and strength estimation are obtained disregarding, as much as possible, the reflections influence. Two simple problems are used to compare the generalized inverse performance with fixed regularization factor to performance obtained using the optimized regularization strategy. Numerical and experimental data are used, and two other strength estimation methods are also evaluated for reference.

  7. Regularization and Migration Policy in Europe

    Directory of Open Access Journals (Sweden)

    Philippe de Bruycker

    2001-05-01

    Full Text Available The following pages present, in a general way, the contents of Regularization of illegal immigrants in the European Union, which includes a comparative synthesis and statistical information for each of the eight countries involved; a description of actions since the beginning of the year 2000; and a systematic analysis of the different categories of foreigners, the types of regularization carried out, and the rules that have governed these actions.In relation to regularization, the author considers the political coherence of the actions taken by the member states as well as how they relate to two ever more crucial aspects of immigration policy –the integration of legal resident immigrants and the fight againstillegal immigration in the context of a control of migratory flows.

  8. Efeitos da natação sobre a independência funcional de pacientes com lesão medular Efectos de la natación sobre la independencia funcional de pacientes con lesión medular Effects of swimming on the functional independence of patients with spinal cord injury

    Directory of Open Access Journals (Sweden)

    Maurício Corte Real da Silva

    2005-08-01

    Full Text Available FUNDAMENTOS E OBJETIVO: O esporte tem um papel fundamental na reabilitação física de pacientes com lesão medular por ampliar as alternativas terapêuticas e favorecer a independência funcional. O estudo tem por objetivo conhecer os efeitos da natação sobre habilidades funcionais de pacientes com lesão medular. MÉTODOS: Foram selecionados 16 pacientes portadores de lesão medular, divididos em dois grupos: experimental e controle. Os grupos foram avaliados por meio da Medida de Independência Funcional (Escala FIM antes e após o procedimento que consistiu em sessões de natação realizadas duas vezes por semana durante quatro meses. RESULTADOS: Os dois grupos apresentaram mudanças nos cuidados com o corpo, transferências, escore motor total e escore total. O grupo experimental apresentou ganho maior nas transferências, escore motor total e escore total. CONCLUSÃO: A atividade de natação foi efetiva na melhora da condição física, trazendo benefícios motores sobre as habilidades funcionais dos participantes do grupo experimental.FUNDAMENTOS Y OBJETIVO: El deporte tiene un papel fundamental en la rehabilitación física de pacientes con lesión medular por ampliar las alternativas terapéuticas y favorecer la independencia funcional. El estudio tiene por objeto conocer los efectos de la natación sobre las habilidades funcionales de los pacientes con lesión medular. MÉTODOS: Fueron seleccionados 16 pacientes portadores de lesión medular divididos en dos grupos: experimental y control. Los grupos fueron evaluados por medio de la Medida de Independencia Funcional (Escala FIM antes y después de un procedimiento que consistió en sesiones de natación realizadas dos veces por semana durante cuatro meses. RESULTADOS: Los dos grupos presentaron cambios en los cuidados con el cuerpo, transferencias, puntaje motor total y puntaje total. El grupo experimental presentó ganancia mayor en las transferencias, puntaje motor total y

  9. Effects of the addition of functional electrical stimulation to ground level gait training with body weight support after chronic stroke Efeitos da adição da estimulação elétrica funcional ao treino de marcha em piso fixo com suporte parcial de peso após acidente vascular encefálico crônico

    Directory of Open Access Journals (Sweden)

    Christiane L. Prado-Medeiros

    2011-12-01

    Full Text Available BACKGROUND: The addition of functional electrical stimulation (FES to treadmill gait training with partial body weight support (BWS has been proposed as a strategy to facilitate gait training in people with hemiparesis. However, there is a lack of studies that evaluate the effectiveness of FES addition on ground level gait training with BWS, which is the most common locomotion surface. OBJECTIVE: To investigate the additional effects of commum peroneal nerve FES combined with gait training and BWS on ground level, on spatial-temporal gait parameters, segmental angles, and motor function. METHODS: Twelve people with chronic hemiparesis participated in the study. An A1-B-A2 design was applied. A1 and A2 corresponded to ground level gait training using BWS, and B corresponded to the same training with the addition of FES. The assessments were performed using the Modified Ashworth Scale (MAS, Functional Ambulation Category (FAC, Rivermead Motor Assessment (RMA, and filming. The kinematics analyzed variables were mean walking speed of locomotion; step length; stride length, speed and duration; initial and final double support duration; single-limb support duration; swing period; range of motion (ROM, maximum and minimum angles of foot, leg, thigh, and trunk segments. RESULTS: There were not changes between phases for the functional assessment of RMA, for the spatial-temporal gait variables and segmental angles, no changes were observed after the addition of FES. CONCLUSION: The use of FES on ground level gait training with BWS did not provide additional benefits for all assessed parameters.CONTEXTUALIZAÇÃO: A adição da estimulação elétrica funcional (EEF ao treino de marcha em esteira, com sistema de suporte parcial de peso corporal (SPPC, tem sido proposta como estratégia para melhorar a marcha em hemiparéticos. Entretanto, nenhum estudo verificou a eficácia da adição da EEF ao treino de marcha com SPPC em piso fixo, a superfície mais

  10. Regular-fat dairy and human health

    DEFF Research Database (Denmark)

    Astrup, Arne; Bradley, Beth H Rice; Brenna, J Thomas

    2016-01-01

    to disseminate, explore and discuss the state of the science on the relationship between regular fat dairy products and health, symposia were programmed by dairy industry organizations in Europe and North America at The Eurofed Lipids Congress (2014) in France, The Dairy Nutrition Annual Symposium (2014......) in Canada, The American Society for Nutrition Annual Meeting held in conjunction with Experimental Biology (2015) in the United States, and The Federation of European Nutrition Societies (2015) in Germany. This synopsis of these symposia describes the complexity of dairy fat and the effects regular...

  11. Deconvolution and Regularization with Toeplitz Matrices

    DEFF Research Database (Denmark)

    Hansen, Per Christian

    2002-01-01

    treatment requires the use of regularization methods. The corresponding computational problem takes the form of structured matrix problem with a Toeplitz or block Toeplitz coefficient matrix. The aim of this paper is to present a tutorial survey of numerical algorithms for the practical treatment...... of these discretized deconvolution problems, with emphasis on methods that take the special structure of the matrix into account. Wherever possible, analogies to classical DFT-based deconvolution problems are drawn. Among other things, we present direct methods for regularization with Toeplitz matrices, and we show...

  12. Regularity and counterfactuality in Hume's treatment of causation

    Directory of Open Access Journals (Sweden)

    José Oscar de Almeida Marques

    2011-12-01

    Full Text Available Of the several theories of causation current in our days, Hume is said to be the inspiration of two of the most influential and accepted: the regularity theory, first clearly formulated by Thomas Brown in 1822, and the counterfactual theory, proposed by David Lewis in 1973. After a brief outline of the comparative merits and difficulties of these two views, I proceed to examine whether Hume's own treatment of causation actually corresponds to any of them. I will show that his first definition of cause, coupled with his rules by which to judge about causes and effects, contains elements that, properly developed, allow us to address successfully some traditional difficulties of the regularity view of causation, without resorting to the conceptual resources employed in the counterfactual approach. Therefore, we can properly classify Hume as an advocate of the conception of causation as regularity, noting however that his primary goal in his research and definitions of the concept was to provide not so much an analysis of causation as such, but of causation as we apprehend it, in the form of our ability to make causal inferences and refine them to reach the more sophisticated causal reasonings that are required in the theoretical and practical issues of life.Das diversas teorias da causação existentes em nossos dias, Hume pode ser considerado o precursor de duas das mais influentes e aceitas: a teoria regularista, formulada claramente pela primeira vez por Thomas Brown, em 1822, e a teoria contrafatualista, proposta por David Lewis em 1973. Depois de um breve resumo dos méritos e dificuldades comparativos dessas duas perspectivas, passo a examinar se o tratamento de Hume da causação corresponde, na verdade a algum deles. Mostro que a sua primeira definição de causa, juntamente com suas regras para julgar sobre as causas e efeitos, contém elementos que, devidamente desenvolvidos, permitem-nos abordar com sucesso algumas dificuldades

  13. On RG-spaces and the regularity degree

    Directory of Open Access Journals (Sweden)

    R. Raphael

    2006-04-01

    Full Text Available We continue the study of a lattice-ordered ring G(X, associated with the ring C(X. Following, X is called RG when G(X = C(Xδ. An RG-space must have a dense set of very weak P-points. It must have a dense set of almost-P-points if Xδ is Lindelöf, or if the continuum hypothesis holds and C(X has small cardinality. Spaces which are RG must have finite Krull dimension when taken with respect to the prime z-ideals of C(X. There is a notion of regularity degree defined via the functions in G(X. Pseudocompact spaces and metric spaces of finite regularity degree are characterized.

  14. SparseBeads data: benchmarking sparsity-regularized computed tomography

    DEFF Research Database (Denmark)

    Jørgensen, Jakob Sauer; Coban, Sophia B.; Lionheart, William R. B.

    2017-01-01

    Sparsity regularization (SR) such as total variation (TV) minimization allows accurate image reconstruction in x-ray computed tomography (CT) from fewer projections than analytical methods. Exactly how few projections suffice and how this number may depend on the image remain poorly understood......, number of projections and noise levels to allow the systematic assessment of parameters affecting performance of SR reconstruction algorithms6. Using the SparseBeads data, TV-regularized reconstruction quality was assessed as a function of numbers of projections and gradient sparsity. The critical number....... Compressive sensing connects the critical number of projections to the image sparsity, but does not cover CT, however empirical results suggest a similar connection. The present work establishes for real CT data a connection between gradient sparsity and the sufficient number of projections for accurate TV...

  15. Comment on "Construction of regular black holes in general relativity"

    Science.gov (United States)

    Bronnikov, Kirill A.

    2017-12-01

    We claim that the paper by Zhong-Ying Fan and Xiaobao Wang on nonlinear electrodynamics coupled to general relativity [Phys. Rev. D 94,124027 (2016)], although correct in general, in some respects repeats previously obtained results without giving proper references. There is also an important point missing in this paper, which is necessary for understanding the physics of the system: in solutions with an electric charge, a regular center requires a non-Maxwell behavior of Lagrangian function L (f ) , (f =Fμ νFμ ν) at small f . Therefore, in all electric regular black hole solutions with a Reissner-Nordström asymptotic, the Lagrangian L (f ) is different in different parts of space, and the electromagnetic field behaves in a singular way at surfaces where L (f ) suffers branching.

  16. Resolving intravoxel fiber architecture using nonconvex regularized blind compressed sensing

    Science.gov (United States)

    Chu, C. Y.; Huang, J. P.; Sun, C. Y.; Liu, W. Y.; Zhu, Y. M.

    2015-03-01

    In diffusion magnetic resonance imaging, accurate and reliable estimation of intravoxel fiber architectures is a major prerequisite for tractography algorithms or any other derived statistical analysis. Several methods have been proposed that estimate intravoxel fiber architectures using low angular resolution acquisitions owing to their shorter acquisition time and relatively low b-values. But these methods are highly sensitive to noise. In this work, we propose a nonconvex regularized blind compressed sensing approach to estimate intravoxel fiber architectures in low angular resolution acquisitions. The method models diffusion-weighted (DW) signals as a sparse linear combination of unfixed reconstruction basis functions and introduces a nonconvex regularizer to enhance the noise immunity. We present a general solving framework to simultaneously estimate the sparse coefficients and the reconstruction basis. Experiments on synthetic, phantom, and real human brain DW images demonstrate the superiority of the proposed approach.

  17. Autocorrelation and regularization in digital images. I - Basic theory

    Science.gov (United States)

    Jupp, David L. B.; Strahler, Alan H.; Woodcock, Curtis E.

    1988-01-01

    Spatial structure occurs in remotely sensed images when the imaged scenes contain discrete objects that are identifiable in that their spectral properties are more homogeneous within than between them and other scene elements. The spatial structure introduced is manifest in statistical measures such as the autocovariance function and variogram associated with the scene, and it is possible to formulate these measures explicitly for scenes composed of simple objects of regular shapes. Digital images result from sensing scenes by an instrument with an associated point spread function (PSF). Since there is averaging over the PSF, the effect, termed regularization, induced in the image data by the instrument will influence the observable autocovariance and variogram functions of the image data. It is shown how the autocovariance or variogram of an image is a composition of the underlying scene covariance convolved with an overlap function, which is itself a convolution of the PSF. The functional form of this relationship provides an analytic basis for scene inference and eventual inversion of scene model parameters from image data.

  18. Robust regularized singular value decomposition with application to mortality data

    KAUST Repository

    Zhang, Lingsong

    2013-09-01

    We develop a robust regularized singular value decomposition (RobRSVD) method for analyzing two-way functional data. The research is motivated by the application of modeling human mortality as a smooth two-way function of age group and year. The RobRSVD is formulated as a penalized loss minimization problem where a robust loss function is used to measure the reconstruction error of a low-rank matrix approximation of the data, and an appropriately defined two-way roughness penalty function is used to ensure smoothness along each of the two functional domains. By viewing the minimization problem as two conditional regularized robust regressions, we develop a fast iterative reweighted least squares algorithm to implement the method. Our implementation naturally incorporates missing values. Furthermore, our formulation allows rigorous derivation of leaveone- row/column-out cross-validation and generalized cross-validation criteria, which enable computationally efficient data-driven penalty parameter selection. The advantages of the new robust method over nonrobust ones are shown via extensive simulation studies and the mortality rate application. © Institute of Mathematical Statistics, 2013.

  19. The effect of gastric dilatation in rats submitted to gasified water ingestion under the hepatic metabolic function Efeito da dilatação gástrica em ratos submetidos à ingestão de água gaseificada sobre a função metabólica hepática

    Directory of Open Access Journals (Sweden)

    José Roberto Ferreira Santiago

    2008-10-01

    Full Text Available INTRODUCTION: The amounts of people that are overweight have been increasing within the population in significant ways during the last decades. In this view, gasified beverages have become an important environmental concern in relation to the eating habits of people, especially who lives in the USA, Mexico, and Brazil. In this order, these three countries constitute the major beverages producers and consumers of the whole world. PURPOSE: To investigate the effects of gastric dilatation in rats submitted to gasified water ingestion, uniform vehicle for all soft drinks, under metabolic patterns of the hepatic function. METHODS: Two groups of 15 rats were formed and observed during two weeks. The rats of the group I, were fed with 200g/day of rat food ad libitum and 100ml of non-gasified water during three daily periods. The rats composing the group II, were fed with 200g/day of rat food ad libitum and 100ml of gasified water within 3 daily periods. The media (x and standard deviation (s were calculated through the paired t-test for each group in order to compare the effects of the different types of water and its effect in each one of them. RESULTS: The results indicated that the animals which were submitted to the treatment with gasified water (G-II, presented an increase of glutamic-pyruvic transaminase (GPT and alkaline phosphatase (ALP (pp>0,05 and increase of the gastric area with macroscopic morphologic alterations, such as the loss of the characteristic linear depressions on the surface of the mucous membrane. CONCLUSION: The gasified water favored the expansion of the gastric area and contributed to the extinction of the linear depressions of the mucous organ, which caused metabolic alterations of the hepatic function.INTRODUÇÃO: O excesso de peso na população aumentou de forma significante nas últimas décadas e as bebidas gasosas tornaram-se um fator ambiental importante no comportamento alimentar das pessoas, sendo os EUA, M

  20. Efeitos do Tratamento Crônico com Sinvastatina na Função Renal de Ratos Submetidos a um Modelo Experimental de Doença Renal Crônica Effects of Chronic Treatment with Sinvastatin on Renal Function in Rats Subjected to an Experimental Model of Chronic Kidney Disease

    Directory of Open Access Journals (Sweden)

    André Luiz Rios dos Santos

    2014-06-01

    Full Text Available Objetivos: Avaliar os efeitos do tratamento crônico com sinvastatina na função renal de ratos submetidos a um modelo experimental de doença renal crônica. Metodologia: Foram utilizados 30 ratos, machos, adultos jovens, da linhagem Wistar, com peso entre 200 e 250 g e idade entre 60 e 90 dias. Os animais foram divididos aleatoriamente em 3 grupos com 10 ratos cada. Foi realizada a cirurgia seguindo o modelo experimental de doença renal crônica moderada (DRC-M baseado na metodologia descrita por Ormrod & Miller, 1980. Após os procedimentos cirúrgicos, os animais receberam os referidos tratamentos, por um período de duas semanas: Grupo 1 - Animais com DRC-M tratados com água destilada VO (Gavagem (n=10. Grupo 2 - Animais com DRC-M tratados com 5mg/Kg de sinvastatina VO (n=10. Grupo 3 - Animais com DRC-M tratados com 10mg/Kg de sinvastatina VO (n=10. Resultados: A indução de DRC-M não produziu alterações significativas sobre o débito urinário, ingesta hídrica, ingesta alimentar e parâmetros da função renal estudados, quando comparados o grupo controle com sinvastatina 5mg/Kg ou com sinvastatina 10mg/Kg ou quando comparados os grupos sinvastatinas entre si. Conclusão: Esses dados demonstram que o tratamento com sinvastatina, independente da dosagem do trabalho, não produziu melhora da função renal de ratos submetidos a um modelo experimental de Doença Renal Crônica Moderada (DRC-M. Objectives: To evaluate the effects of chronic treatment with sinvastatin on renal function in rats subjected to an experimental model of chronic renal disease. Methods: 30 male rats were young adults, the Wistar strain, weighing between 200 and 250 g and aged between 60 and 90 days were used. The animals were randomly divided into 3 groups with 10 rats in each. Surgery was performed following the experimental moderate chronic (CKD-M model of kidney disease based on the methodology described by Miller & Ormrod, 1980. After the surgical

  1. Orientating Children in Regular Schools towards Impairments.

    Science.gov (United States)

    Gorman, P. P.

    1979-01-01

    The author discusses audio-visual material and other education techniques which eventually may facilitate the integration of children with mental, physical, and sensory impairments in the regular classroom. Films, radio texts, theater plays, and books are considered. Emphasis is on the introduction of impairments to the nonhandicapped population.…

  2. Regular ultrafilters and finite square principles

    NARCIS (Netherlands)

    Kennedy, J.; Shelah, S.; Väänänen, J.

    2008-01-01

    We show that many singular cardinals lambda above a strongly compact cardinal have regular ultrafilters D that violate the finite square principle square(fin)(lambda,D) introduced in [3]. For such ultrafilters D and cardinals lambda there are models of size lambda for which M-lambda/D is not

  3. Broad temperature range antiferroelectric regular mixtures

    Science.gov (United States)

    Dabrowski, Roman; Czuprynski, Krzysztof; Gasowska, J.; Oton, Jose; Quintana, Xabier; Castillo, P. L.; Bennis, N.

    2004-09-01

    Tristate regular mixtures with different electro-optical properties such as threshold voltage, saturation voltage, holding ratio and response time are presented. The relation of properties with the structure of compounds is discussed. All of mixtures show only moderate dynamic and static contrast but big gray level scale without hysteresis for positive and negative field driving.

  4. Regular matrix transformation on triple sequence spaces

    Directory of Open Access Journals (Sweden)

    Shyamal Debnath

    2017-10-01

    Full Text Available The main aim of this paper is to introduce the necessary and sufficient condition for a particular type of transformation of the form A: (a......  be regular from a triple sequence space to another triple sequence space.

  5. Regular and context-free nominal traces

    DEFF Research Database (Denmark)

    Degano, Pierpaolo; Ferrari, Gian-Luigi; Mezzetti, Gianluca

    2017-01-01

    Two kinds of automata are presented, for recognising new classes of regular and context-free nominal languages. We compare their expressive power with analogous proposals in the literature, showing that they express novel classes of languages. Although many properties of classical languages hold ...

  6. On bigraded regularities of Rees algebra

    Indian Academy of Sciences (India)

    Ramakrishna Nanduri

    2017-08-03

    Aug 3, 2017 ... K-algebra were defined in terms of syzygies [18, Definition 5.4] (also see [10, Defini- tion 1.1.3]). Since R(I) ... way (see Definition 2.3). We also define the Tor bigraded regularities of R; see ...... referee for a thorough reading of the manuscript and suggesting some improvements. References. [1] Aramova A ...

  7. From recreational to regular drug use

    DEFF Research Database (Denmark)

    Järvinen, Margaretha; Ravn, Signe

    2011-01-01

    to extricate themselves from this pattern. Hence, when regular drug users talk about their future, it is not a future characterised by total abstinence from illegal drugs but a future where they have rolled back their drug use career to the recreational drug use pattern they started out with. Empirically...

  8. On regular riesz operators | Raubenheimer | Quaestiones ...

    African Journals Online (AJOL)

    The r-asymptotically quasi finite rank operators on Banach lattices are examples of regular Riesz operators. We characterise Riesz elements in a subalgebra of a Banach algebra in terms of Riesz elements in the Banach algebra. This enables us to characterise r-asymptotically quasi finite rank operators in terms of adjoint ...

  9. Regular Sleep Makes for Happier College Students

    Science.gov (United States)

    ... https://medlineplus.gov/news/fullstory_166856.html Regular Sleep Makes for Happier College Students When erratic snoozers improve shut-eye habits, ... Health and Human Services. More Health News on College Health Healthy Sleep Recent Health News Related MedlinePlus Health Topics College ...

  10. 28 CFR 540.44 - Regular visitors.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Regular visitors. 540.44 Section 540.44... and if there exists no reason to exclude them. (c) Friends and associates. The visiting privilege ordinarily will be extended to friends and associates having an established relationship with the inmate...

  11. Neural Classifier Construction using Regularization, Pruning

    DEFF Research Database (Denmark)

    Hintz-Madsen, Mads; Hansen, Lars Kai; Larsen, Jan

    1998-01-01

    In this paper we propose a method for construction of feed-forward neural classifiers based on regularization and adaptive architectures. Using a penalized maximum likelihood scheme, we derive a modified form of the entropic error measure and an algebraic estimate of the test error. In conjunction...

  12. Regularization algorithms based on total least squares

    DEFF Research Database (Denmark)

    Hansen, Per Christian; O'Leary, Dianne P.

    1996-01-01

    or truncated {\\em SVD}, are not designed for problems in which both the coefficient matrix and the right-hand side are known only approximately. For this reason, we develop {\\em TLS}\\/-based regularization methods that take this situation into account. Here, we survey two different approaches to incorporation...

  13. Stabilization, pole placement, and regular implementability

    NARCIS (Netherlands)

    Belur, MN; Trentelman, HL

    In this paper, we study control by interconnection of linear differential systems. We give necessary and sufficient conditions for regular implementability of a-given linear, differential system. We formulate the problems of stabilization and pole placement as problems of finding a suitable,

  14. Stabilization, Pole Placement, and Regular Implementability

    NARCIS (Netherlands)

    Belur, Madhu N.; Trentelman, H.L.

    2002-01-01

    In this paper, we study control by interconnection of linear differential systems. We give necessary and sufficient conditions for regular implementability of a given linear differential system. We formulate the problems of stabilization and pole placement as problems of finding a suitable,

  15. A Sim(2 invariant dimensional regularization

    Directory of Open Access Journals (Sweden)

    J. Alfaro

    2017-09-01

    Full Text Available We introduce a Sim(2 invariant dimensional regularization of loop integrals. Then we can compute the one loop quantum corrections to the photon self energy, electron self energy and vertex in the Electrodynamics sector of the Very Special Relativity Standard Model (VSRSM.

  16. Annotation of regular polysemy and underspecification

    DEFF Research Database (Denmark)

    Martínez Alonso, Héctor; Pedersen, Bolette Sandford; Bel, Núria

    2013-01-01

    We present the result of an annotation task on regular polysemy for a series of seman- tic classes or dot types in English, Dan- ish and Spanish. This article describes the annotation process, the results in terms of inter-encoder agreement, and the sense distributions obtained with two methods...

  17. Efeito de um programa de exercício físico de longa duração no controlo glicémico de doentes com diabetes mellitus do tipo 2

    OpenAIRE

    Magalhães, Pedro M.; Duarte, José Alberto; Lopes, Vítor P.

    2010-01-01

    Os efeitos benéficos da prática regular de exercício físico (EF) na melhoria do controlo glicémico em doentes com diabetes mellitus do tipo 2 (DM2), estão relativamente bem documentados na literatura, nomeadamente em programas de curta e média duração. Menos consenso existe relativamente ao longo prazo. No presente estudo, procurou-se avaliar os efeitos de um programa de EF regular de longa duração no controlo glicémico em doentes com DM2. A amostra foi constituída por um grupo de referência ...

  18. A novel kernel regularized nonhomogeneous grey model and its applications

    Science.gov (United States)

    Ma, Xin; Hu, Yi-sheng; Liu, Zhi-bin

    2017-07-01

    The nonhomogeneous grey model (NGM) is a novel tool for time series forecasting, which has attracted considerable interest of research. However, the existing nonhomogeneous grey models may be inefficient to predict the complex nonlinear time series sometimes due to the linearity of the differential or difference equations based on which these models are developed. In order to enhance the accuracy and applicability of the NGM model, the kernel method in the statistical learning theory has been utilized to build a novel kernel regularized nonhomogeneous grey model, which is abbreviated as the KRNGM model. The KRNGM model is represented by a differential equation which contains a nonlinear function of t. By constructing the regularized problem and using the kernel function which satisfies the Mercer's condition, the parameters estimation of KRNGM model only involves in solving a set of linear equations, and the nonlinear function in the KRNGM model can be expressed as a linear combination of the Lagrangian multipliers and the selected kernel function, and then the KRNGM model can be solved numerically. Two case studies of petroleum production forecasting are carried to illustrate the effectiveness of the KRNGM model, comparing to the existing nonhomogeneous models. The results show that the KRNGM model outperforms the existing NGM, ONGM, NDGM model significantly.

  19. Effect of a low-dose oral contraceptive on venous endothelial function in healthy young women: preliminary results Efeito de um anticoncepcional hormonal oral de baixa dose na função endotelial venosa em mulheres jovens saudáveis: resultados preliminares

    Directory of Open Access Journals (Sweden)

    Cassiana Rosa Galvão Giribela

    2007-01-01

    Full Text Available BACKGROUND: A possible increase in the incidence of venous thromboembolic events has been reported among users of third generation oral contraceptives. The objective of this study was to evaluate the effect of a low dose oral contraceptive (15 µg ethinyl estradiol/60 µg gestodene on the venous endothelial function of healthy young women. METHODS: Prospective case control study using the dorsal hand vein technique. Venous endothelial function was evaluated at baseline and after 4 months in the oral contraceptive users group (11 women and in a control group (9 women. After preconstriction of the vein with phenylephrine, dose-response curves for acetylcholine and sodium nitroprusside were constructed. RESULTS: In the contraceptive users group, a reduction occurred in the maximum venodilation response to acetylcholine and sodium nitroprusside after 4 months of oral contraceptive use, but this difference was not statistically significant (P > 0.05. No significant changes were detected in maximum venodilation responses to acetylcholine and sodium nitroprusside at the 4-month time point in the control group. CONCLUSION: This study found no significant impairment of endothelium-dependent or independent venodilation in healthy young women following oral contraceptive use. Further studies are necessary using the same methodology in a larger sample over a longer follow-up period.Um aumento no risco de tromboembolismo venoso têm sido descrito em usuárias de anticoncepcionais hormonais oral de terceira geração. OBJETIVO: Avaliar o efeito de um anticoncepcional combinado hormonal oral de baixa dose (15 µg etinil estradiol/60 µg gestodeno na função endotelial venosa de mulheres jovens saudáveis. MÉTODOS: Realizou-se um estudo caso-controle prospectivo em vinte mulheres jovens saudáveis que foram avaliadas pela técnica da complascência venosa. A função endotelial venosa foi avaliada em um momento basal e após 4 meses no grupo das usuárias de

  20. Avaliação por tomografia computadorizada helicoidal dos efeitos da expansão rápida da maxila no posicionamento condilar em pacientes com mordida cruzada posterior funcional Evaluation with helicoidal computed tomography of rapid maxillary expansion effects in the condylar position of patients with functional posterior crossbite

    Directory of Open Access Journals (Sweden)

    Edgard Norões Rodrigues da Matta

    2009-10-01

    Full Text Available OBJETIVO: este estudo clínico avaliou, por meio da tomografia computadorizada helicoidal, os efeitos da expansão rápida da maxila no posicionamento condilar de pacientes com mordida cruzada posterior funcional na fase da dentadura mista. MÉTODOS: dez pacientes com faixa etária entre os 7 anos e 2 meses e os 11 anos e 2 meses - apresentando mordida cruzada posterior funcional, com desvio da linha média de pelo menos 2,5mm para o lado do cruzamento - foram tratados com expansão rápida da maxila. Após a obtenção de cortes tomográficos sagitais da articulação temporomandibular, as medidas dos espaços articulares anterior, posterior e superior foram realizadas e o posicionamento relativo do côndilo foi calculado. Utilizando-se cortes tomográficos axiais, avaliou-se o posicionamento anteroposterior e transversal dos côndilos em relação às estruturas da base craniana. RESULTADOS: foram identificadas diferenças significativas, antes do tratamento, entre os espaços articulares posteriores, na posição relativa do côndilo e um posicionamento mais anterior e mais próximo ao plano sagital mediano do côndilo do lado não-cruzado. Após o tratamento, não foram evidenciadas diferenças significativas nessas medidas. CONCLUSÕES: após a expansão rápida da maxila, um posicionamento mais centralizado dos côndilos nas fossas articulares foi observado, além de uma maior simetria anteroposterior e transversal entre os mesmos.AIM: This clinical study evaluated, through helicoidal computed tomography (CT, the effects of rapid maxillary expansion in the condylar position of patients with functional posterior crossbite in mixed dentition stage. METHODS: Ten patients aged between 7 years and 2 months and 11 years and 2 months were selected. This patients which presented functional unilateral posterior crossbite with mandibular midline deviation of at least 2.5mm to the crossbite side were submitted to rapid maxillary expansion. After

  1. Real time QRS complex detection using DFA and regular grammar.

    Science.gov (United States)

    Hamdi, Salah; Ben Abdallah, Asma; Bedoui, Mohamed Hedi

    2017-02-28

    The sequence of Q, R, and S peaks (QRS) complex detection is a crucial procedure in electrocardiogram (ECG) processing and analysis. We propose a novel approach for QRS complex detection based on the deterministic finite automata with the addition of some constraints. This paper confirms that regular grammar is useful for extracting QRS complexes and interpreting normalized ECG signals. A QRS is assimilated to a pair of adjacent peaks which meet certain criteria of standard deviation and duration. The proposed method was applied on several kinds of ECG signals issued from the standard MIT-BIH arrhythmia database. A total of 48 signals were used. For an input signal, several parameters were determined, such as QRS durations, RR distances, and the peaks' amplitudes. σRR and σQRS parameters were added to quantify the regularity of RR distances and QRS durations, respectively. The sensitivity rate of the suggested method was 99.74% and the specificity rate was 99.86%. Moreover, the sensitivity and the specificity rates variations according to the Signal-to-Noise Ratio were performed. Regular grammar with the addition of some constraints and deterministic automata proved functional for ECG signals diagnosis. Compared to statistical methods, the use of grammar provides satisfactory and competitive results and indices that are comparable to or even better than those cited in the literature.

  2. A regularized tri-linear approach for optical interferometric imaging

    Science.gov (United States)

    Birdi, Jasleen; Repetti, Audrey; Wiaux, Yves

    2017-06-01

    In the context of optical interferometry, only undersampled power spectrum and bispectrum data are accessible. It poses an ill-posed inverse problem for image recovery. Recently, a tri-linear model was proposed for monochromatic imaging, leading to an alternated minimization problem. In that work, only a positivity constraint was considered, and the problem was solved by an approximated Gauss-Seidel method. In this paper, we propose to improve the approach on three fundamental aspects. First, we define the estimated image as a solution of a regularized minimization problem, promoting sparsity in a fixed dictionary using either an ℓ1 or a (re)weighted-ℓ1 regularization term. Secondly, we solve the resultant non-convex minimization problem using a block-coordinate forward-backward algorithm. This algorithm is able to deal both with smooth and non-smooth functions, and benefits from convergence guarantees even in a non-convex context. Finally, we generalize our model and algorithm to the hyperspectral case, promoting a joint sparsity prior through an ℓ2,1 regularization term. We present simulation results, both for monochromatic and hyperspectral cases, to validate the proposed approach.

  3. Thin-shell wormholes from the regular Hayward black hole

    Energy Technology Data Exchange (ETDEWEB)

    Halilsoy, M.; Ovgun, A.; Mazharimousavi, S.H. [Eastern Mediterranean University, Department of Physics, Mersin 10 (Turkey)

    2014-03-15

    We revisit the regular black hole found by Hayward in 4-dimensional static, spherically symmetric spacetime. To find a possible source for such a spacetime we resort to the nonlinear electrodynamics in general relativity. It is found that a magnetic field within this context gives rise to the regular Hayward black hole. By employing such a regular black hole we construct a thin-shell wormhole for the case of various equations of state on the shell. We abbreviate a general equation of state by p = ψ(σ) where p is the surface pressure which is a function of the mass density (σ). In particular, linear, logarithmic, Chaplygin, etc. forms of equations of state are considered. In each case we study the stability of the thin shell against linear perturbations.We plot the stability regions by tuning the parameters of the theory. It is observed that the role of the Hayward parameter is to make the TSW more stable. Perturbations of the throat with small velocity condition are also studied. The matter of our TSWs, however, remains exotic. (orig.)

  4. Image reconstruction from incomplete convolution data via total variation regularization

    Directory of Open Access Journals (Sweden)

    Zhida Shen

    2015-02-01

    Full Text Available Variational models with Total Variation (TV regularization have long been known to preserve image edges and produce high quality reconstruction. On the other hand, recent theory on compressive sensing has shown that it is feasible to accurately reconstruct  images from a few linear measurements via TV regularization. However, in general TV models are difficult to solve due to the nondifferentiability and the universal coupling of variables. In this paper, we propose the use of alternating direction method for image reconstruction from highly incomplete convolution data, where an image is reconstructed as a minimizer of an energy function that sums   a TV term for image regularity and a least squares term for data fitting. Our algorithm, called RecPK, takes advantage of problem structures and has an extremely low per-iteration cost. To demonstrate the efficiency of RecPK, we  compare it with TwIST, a state-of-the-art algorithm for minimizing TV models. Moreover, we also demonstrate the usefulness of RecPK in image zooming.

  5. Regularity and predictability of human mobility in personal space.

    Directory of Open Access Journals (Sweden)

    Daniel Austin

    Full Text Available Fundamental laws governing human mobility have many important applications such as forecasting and controlling epidemics or optimizing transportation systems. These mobility patterns, studied in the context of out of home activity during travel or social interactions with observations recorded from cell phone use or diffusion of money, suggest that in extra-personal space humans follow a high degree of temporal and spatial regularity - most often in the form of time-independent universal scaling laws. Here we show that mobility patterns of older individuals in their home also show a high degree of predictability and regularity, although in a different way than has been reported for out-of-home mobility. Studying a data set of almost 15 million observations from 19 adults spanning up to 5 years of unobtrusive longitudinal home activity monitoring, we find that in-home mobility is not well represented by a universal scaling law, but that significant structure (predictability and regularity is uncovered when explicitly accounting for contextual data in a model of in-home mobility. These results suggest that human mobility in personal space is highly stereotyped, and that monitoring discontinuities in routine room-level mobility patterns may provide an opportunity to predict individual human health and functional status or detect adverse events and trends.

  6. [Depression in young regular cocaine users recruited in the community].

    Science.gov (United States)

    Chahua, Marcela; Sordo, Luis; Molist, Gemma; Domingo-Salvany, Antonia; Brugal, María Teresa; de la Fuente, Luis; Bravo, María José

    2014-01-01

    To identify the profile of community-recruited regular cocaine users and the prevalence of recent depression and associated factors. A cross-sectional study was carried out in 630 regular cocaine users who were not heroin consumers. Depression, social support and dependence were evaluated with the Composite International Diagnostic Interview, the Duke-Functional Social Support Questionnaire, and the Severity of Dependence Scale, respectively. The mean age was 23 years and 33% of users were women. The predominant profile of cocaine use was recreational-intense. Most (88%) participants had completed secondary education. The use of emergency services in the previous year was 45.9% and 7.8% were under drug-dependence/psychiatric treatment. The prevalence of depression was 14.6%. In the multivariate analysis, the factors associated with recent depression were female gender, homelessness, ketamine consumption, and less confidential support Regular cocaine users may require specific attention in general health services. Greater access to treatment for depression is needed among this group. Copyright © 2013 SESPAS. Published by Elsevier Espana. All rights reserved.

  7. Regularity and predictability of human mobility in personal space.

    Science.gov (United States)

    Austin, Daniel; Cross, Robin M; Hayes, Tamara; Kaye, Jeffrey

    2014-01-01

    Fundamental laws governing human mobility have many important applications such as forecasting and controlling epidemics or optimizing transportation systems. These mobility patterns, studied in the context of out of home activity during travel or social interactions with observations recorded from cell phone use or diffusion of money, suggest that in extra-personal space humans follow a high degree of temporal and spatial regularity - most often in the form of time-independent universal scaling laws. Here we show that mobility patterns of older individuals in their home also show a high degree of predictability and regularity, although in a different way than has been reported for out-of-home mobility. Studying a data set of almost 15 million observations from 19 adults spanning up to 5 years of unobtrusive longitudinal home activity monitoring, we find that in-home mobility is not well represented by a universal scaling law, but that significant structure (predictability and regularity) is uncovered when explicitly accounting for contextual data in a model of in-home mobility. These results suggest that human mobility in personal space is highly stereotyped, and that monitoring discontinuities in routine room-level mobility patterns may provide an opportunity to predict individual human health and functional status or detect adverse events and trends.

  8. Iterative CT Reconstruction Using Shearlet-Based Regularization

    Science.gov (United States)

    Vandeghinste, Bert; Goossens, Bart; Van Holen, Roel; Vanhove, Christian; Pižurica, Aleksandra; Vandenberghe, Stefaan; Staelens, Steven

    2013-10-01

    Total variation (TV) methods have been proposed to improve the image quality in count-reduced images, by reducing the variation between neighboring pixels. Although very easy to implement and fast to compute, TV-based methods may lead to a loss of texture information when applied to images with complex textures, such as high-resolution abdominal CT images. Here, we investigate the use of another regularization approach in the context of medical images based on multiresolution transformations. One such transformation is the shearlet transform, which is optimally sparse for images that are C2 except for discontinuities along C2 curves, and has better directional sensitivity than most other, related, wavelet transform approaches. We propose to solve the convex problem using the split-Bregman (augmented Lagrangian) approach. One of the primary advantages of the split-Bregman approach, is that the shearlet transform can easily be incorporated into the sparse-view CT reconstruction. The required sparsity prior is the l1 norm of the shearlet coefficients. Results are shown for this method in comparison to the same framework with TV as the regularization term on simulated data. The noise-resolution performance is investigated at different contrast levels. At equal image noise, TV-based regularization outperforms shearlet-based regularization. However, when image texture is analyzed on measured mouse data, shearlets outperform TV, which suffers from staircasing effects. Our results show that there are benefits in using shearlets in CT imaging: texture is reconstructed more accurately compared to when TV is used, without biasing the image towards a piecewise constant image model. However, due to the larger support of the basis functions, our results suggest that uncareful usage of shearlets may lead to wavy artifacts, which can be equally unwanted as staircasing effects.

  9. SparseBeads data: benchmarking sparsity-regularized computed tomography

    Science.gov (United States)

    Jørgensen, Jakob S.; Coban, Sophia B.; Lionheart, William R. B.; McDonald, Samuel A.; Withers, Philip J.

    2017-12-01

    Sparsity regularization (SR) such as total variation (TV) minimization allows accurate image reconstruction in x-ray computed tomography (CT) from fewer projections than analytical methods. Exactly how few projections suffice and how this number may depend on the image remain poorly understood. Compressive sensing connects the critical number of projections to the image sparsity, but does not cover CT, however empirical results suggest a similar connection. The present work establishes for real CT data a connection between gradient sparsity and the sufficient number of projections for accurate TV-regularized reconstruction. A collection of 48 x-ray CT datasets called SparseBeads was designed for benchmarking SR reconstruction algorithms. Beadpacks comprising glass beads of five different sizes as well as mixtures were scanned in a micro-CT scanner to provide structured datasets with variable image sparsity levels, number of projections and noise levels to allow the systematic assessment of parameters affecting performance of SR reconstruction algorithms6. Using the SparseBeads data, TV-regularized reconstruction quality was assessed as a function of numbers of projections and gradient sparsity. The critical number of projections for satisfactory TV-regularized reconstruction increased almost linearly with the gradient sparsity. This establishes a quantitative guideline from which one may predict how few projections to acquire based on expected sample sparsity level as an aid in planning of dose- or time-critical experiments. The results are expected to hold for samples of similar characteristics, i.e. consisting of few, distinct phases with relatively simple structure. Such cases are plentiful in porous media, composite materials, foams, as well as non-destructive testing and metrology. For samples of other characteristics the proposed methodology may be used to investigate similar relations.

  10. Association Between Regular Cannabis Use and Ganglion Cell Dysfunction.

    Science.gov (United States)

    Schwitzer, Thomas; Schwan, Raymund; Albuisson, Eliane; Giersch, Anne; Lalanne, Laurence; Angioi-Duprez, Karine; Laprevote, Vincent

    2017-01-01

    Because cannabis use is a major public health concern and cannabis is known to act on central neurotransmission, studying the retinal ganglion cells in individuals who regularly use cannabis is of interest. To determine whether the regular use of cannabis could alter the function of retinal ganglion cells in humans. For this case-control study, individuals who regularly use cannabis, as well as healthy controls, were recruited, and data were collected from February 11 to October 28, 2014. Retinal function was used as a direct marker of brain neurotransmission abnormalities in complex mental phenomena. Amplitude and implicit time of the N95 wave on results of pattern electroretinography. Twenty-eight of the 52 participants were regular cannabis users (24 men and 4 women; median age, 22 years [95% CI, 21-24 years]), and the remaining 24 were controls (20 men and 4 women; median age, 24 years [95% CI, 23-27 years]). There was no difference between groups in terms of age (P = .13) or sex (P = .81). After adjustment for the number of years of education and alcohol use, there was a significant increase for cannabis users of the N95 implicit time on results of pattern electroretinography (median, 98.6 milliseconds [95% CI, 93.4-99.5]) compared with controls (median, 88.4 milliseconds [95% CI, 85.0-91.1]), with 8.4 milliseconds as the median of the differences (95% CI, 4.9-11.5; P cannabis users and controls in their corresponding group. The positive predictive value was 78.6% (95% CI, 60.5%-89.8%), and the negative predictive value was 75.0% (95% CI, 55.1%-88.0%). Our results demonstrate a delay in transmission of action potentials by the ganglion cells in regular cannabis users, which could support alterations in vision. Our findings may be important from a public health perspective since they could highlight the neurotoxic effects of cannabis use on the central nervous system as a result of how it affects retinal processing.

  11. Efeitos do manejo comportamental de incontinência fecal em adolescente

    Directory of Open Access Journals (Sweden)

    Anderson Jonas das Neves

    Full Text Available A incontinência fecal, também conhecida como encoprese, é um transtorno de evacuação que acarreta prejuízos ao desenvolvimento psicossocial e orgânico da criança e do adolescente, e que demanda atenção e cuidado de pais e profissionais de saúde. No amplo contexto de tratamento da encoprese, a psicoterapia constitui importante recurso, sendo a terapia comportamental apontada como uma das modalidades mais promissoras e eficazes para o tratamento dessa dificuldade de eliminação. Este artigo apresenta o estudo dos efeitos do manejo comportamental de quadro de incontinência fecal em um adolescente de 14 anos, atendido em clínica-escola de Psicologia do interior do Estado de São Paulo durante 14 meses. A partir do referencial teórico da análise do comportamento, foi desenvolvido, em contexto psicoterápico, um conjunto de estratégias comportamentais com o cliente, bem como orientações aos pais, visando à gradativa extinção encoprética. No decorrer desse processo, o cliente apresentou significativas aquisições comportamentais de uso regular do banheiro e adequado controle esfincteriano, monitoradas semanalmente, que possibilitaram a plena extinção das ocorrências de sujidade, sendo avaliado o efeito em follow-up realizado três meses após o encerramento dessa intervenção.

  12. Regular Magnetic Black Hole Gravitational Lensing

    Science.gov (United States)

    Liang, Jun

    2017-05-01

    The Bronnikov regular magnetic black hole as a gravitational lens is studied. In nonlinear electrodynamics, photons do not follow null geodesics of background geometry, but move along null geodesics of a corresponding effective geometry. To study the Bronnikov regular magnetic black hole gravitational lensing in the strong deflection limit, the corresponding effective geometry should be obtained firstly. This is the most important and key step. We obtain the deflection angle in the strong deflection limit, and further calculate the angular positions and magnifications of relativistic images as well as the time delay between different relativistic images. The influence of the magnetic charge on the black hole gravitational lensing is also discussed. Supported by the Natural Science Foundation of Education Department of Shannxi Province under Grant No 15JK1077, and the Doctorial Scientific Research Starting Fund of Shannxi University of Science and Technology under Grant No BJ12-02.

  13. Exploring the structural regularities in networks

    CERN Document Server

    Shen, Hua-Wei; Guo, Jia-Feng

    2011-01-01

    In this paper, we consider the problem of exploring structural regularities of networks by dividing the nodes of a network into groups such that the members of each group have similar patterns of connections to other groups. Specifically, we propose a general statistical model to describe network structure. In this model, group is viewed as hidden or unobserved quantity and it is learned by fitting the observed network data using the expectation-maximization algorithm. Compared with existing models, the most prominent strength of our model is the high flexibility. This strength enables it to possess the advantages of existing models and overcomes their shortcomings in a unified way. As a result, not only broad types of structure can be detected without prior knowledge of what type of intrinsic regularities exist in the network, but also the type of identified structure can be directly learned from data. Moreover, by differentiating outgoing edges from incoming edges, our model can detect several types of stru...

  14. Modeling Regular Replacement for String Constraint Solving

    Science.gov (United States)

    Fu, Xiang; Li, Chung-Chih

    2010-01-01

    Bugs in user input sanitation of software systems often lead to vulnerabilities. Among them many are caused by improper use of regular replacement. This paper presents a precise modeling of various semantics of regular substitution, such as the declarative, finite, greedy, and reluctant, using finite state transducers (FST). By projecting an FST to its input/output tapes, we are able to solve atomic string constraints, which can be applied to both the forward and backward image computation in model checking and symbolic execution of text processing programs. We report several interesting discoveries, e.g., certain fragments of the general problem can be handled using less expressive deterministic FST. A compact representation of FST is implemented in SUSHI, a string constraint solver. It is applied to detecting vulnerabilities in web applications

  15. Effort variation regularization in sound field reproduction

    DEFF Research Database (Denmark)

    Stefanakis, Nick; Jacobsen, Finn; Sarris, Ioannis

    2010-01-01

    . Specifically, it is suggested that the phase differential of the source driving signals should be in agreement with the phase differential of the desired sound pressure field. The performance of the suggested method is compared with that of conventional effort regularization, wave field synthesis (WFS......In this paper, active control is used in order to reproduce a given sound field in an extended spatial region. A method is proposed which minimizes the reproduction error at a number of control positions with the reproduction sources holding a certain relation within their complex strengths......), and adaptive wave field synthesis (AWFS), both under free-field conditions and in reverberant rooms. It is shown that effort variation regularization overcomes the problems associated with small spaces and with a low ratio of direct to reverberant energy, improving thus the reproduction accuracy...

  16. Chiral Perturbation Theory With Lattice Regularization

    CERN Document Server

    Ouimet, P P A

    2005-01-01

    In this work, alternative methods to regularize chiral perturbation theory are discussed. First, Long Distance Regularization will be considered in the presence of the decuplet of the lightest spin 32 baryons for several different observables. This serves motivation and introduction to the use of the lattice regulator for chiral perturbation theory. The mesonic, baryonic and anomalous sectors of chiral perturbation theory will be formulated on a lattice of space time points. The consistency of the lattice as a regulator will be discussed in the context of the meson and baryon masses. Order a effects will also be discussed for the baryon masses, sigma terms and magnetic moments. The work will close with an attempt to derive an effective Wess-Zumino-Witten Lagrangian for Wilson fermions at non-zero a. Following this discussion, there will be a proposal for a phenomenologically useful WZW Lagrangian at non-zero a.

  17. Testing the Equivalence of Regular Languages

    Directory of Open Access Journals (Sweden)

    Marco Almeida

    2009-07-01

    Full Text Available The minimal deterministic finite automaton is generally used to determine regular languages equality. Antimirov and Mosses proposed a rewrite system for deciding regular expressions equivalence of which Almeida et al. presented an improved variant. Hopcroft and Karp proposed an almost linear algorithm for testing the equivalence of two deterministic finite automata that avoids minimisation. In this paper we improve the best-case running time, present an extension of this algorithm to non-deterministic finite automata, and establish a relationship between this algorithm and the one proposed in Almeida et al. We also present some experimental comparative results. All these algorithms are closely related with the recent coalgebraic approach to automata proposed by Rutten.

  18. Os efeitos do estresse na função do eixo hipotalâmico-pituitário-adrenal em indivíduos com esquizofrenia The effects of stress on hypothalamic-pituitary-adrenal (HPA axis function in subjects with schizophrenia

    Directory of Open Access Journals (Sweden)

    Francesca L. Guest

    2012-01-01

    Full Text Available Nas últimas décadas, têm surgido evidências sugerindo que a patogênese de desordens psiquiátricas, tais como a esquizofrenia, pode envolver perturbações no eixo hipotalâmico-pituitário-adrenal (HPA. Variações na manifestação desses efeitos poderiam estar relacionadas a diferenças em sintomas clínicos entre os indivíduos afetados, assim como a diferenças na resposta ao tratamento. Tais efeitos podem também ser originados de complexas interações entre genes e fatores ambientais. Aqui, revisamos os efeitos do estresse maternal em anormalidades na regulação do eixo HPA e desenvolvimento de desordens psiquiátricas, incluindo a esquizofrenia. Estudos nessa área podem gerar o aumento do nosso entendimento da natureza multidimensional da esquizofrenia. Posterior pesquisa nesse campo poderia, em última instância, levar ao desenvolvimento de melhores diagnósticos e novas abordagens terapêuticas para essa debilitante condição psiquiátrica.Over the last few decades, evidence has been emerging that the pathogenesis of psychiatric disorders such as schizophrenia can involve perturbations of the hypothalamic-pituitary-adrenal (HPA axis. Variations in the manifestation of these effects could be related to the differences in clinical symptoms between affected individuals as well as to differences in treatment response. Such effects can also arise from the complex interaction between genes and environmental factors. Here, we review the effects of maternal stress on abnormalities in HPA axis regulation and the development of psychiatric disorders including schizophrenia. Studies in this area may prove critical for increasing our understanding of the multi-dimensional nature of schizophrenia. Further research in this area could ultimately lead to the development of improved diagnostics and novel therapeutic approaches for treating this debilitating psychiatric condition.

  19. Os efeitos do estresse na função do eixo hipotalâmico-pituitário-adrenal em indivíduos com esquizofrenia The effects of stress on hypothalamic-pituitary-adrenal (HPA axis function in subjects with schizophrenia

    Directory of Open Access Journals (Sweden)

    Francesca L. Guest

    2013-01-01

    Full Text Available Nas últimas décadas, têm surgido evidências sugerindo que a patogênese de desordens psiquiátricas, tais como a esquizofrenia, pode envolver perturbações no eixo hipotalâmico-pituitário-adrenal (HPA. Variações na manifestação desses efeitos poderiam estar relacionadas a diferenças em sintomas clínicos entre os indivíduos afetados, assim como a diferenças na resposta ao tratamento. Tais efeitos podem também ser originados de complexas interações entre genes e fatores ambientais. Aqui, revisamos os efeitos do estresse maternal em anormalidades na regulação do eixo HPA e desenvolvimento de desordens psiquiátricas, incluindo a esquizofrenia. Estudos nessa área podem gerar o aumento do nosso entendimento da natureza multidimensional da esquizofrenia. Posterior pesquisa nesse campo poderia, em última instância, levar ao desenvolvimento de melhores diagnósticos e novas abordagens terapêuticas para essa debilitante condição psiquiátrica.Over the last few decades, evidence has been emerging that the pathogenesis of psychiatric disorders such as schizophrenia can involve perturbations of the hypothalamic-pituitary-adrenal (HPA axis. Variations in the manifestation of these effects could be related to the differences in clinical symptoms between affected individuals as well as to differences in treatment response. Such effects can also arise from the complex interaction between genes and environmental factors. Here, we review the effects of maternal stress on abnormalities in HPA axis regulation and the development of psychiatric disorders including schizophrenia. Studies in this area may prove critical for increasing our understanding of the multi-dimensional nature of schizophrenia. Further research in this area could ultimately lead to the development of improved diagnostics and novel therapeutic approaches for treating this debilitating psychiatric condition.

  20. Lobectomia temporal no infarto cerebral com efeito de massa

    OpenAIRE

    Luis Fernando Martins; Valter da Costa; Joaquim da Costa; Sebastião Eurico de Melo-Souza

    1993-01-01

    Uma complicação frequentemente fatal do infarto isquêmico extenso é o desenvolvimento de efeito de massa por edema. O componente de «swelling» pode ser combatido, mas o edema isquêmico citotóxico dos primeiros dias não responde ao tratamento clínico. Este estudo mostra o resultado da abordagem cirúrgica em casos com deterioração clínica e grande efeito de massa à tomografia computadorizada, nos quais se procedeu a lobectomia temporal do lado do infarto, com finalidade descompressiva. Dos 8 ca...

  1. Regularization in Orbital Mechanics; Theory and Practice

    Science.gov (United States)

    Roa, Javier

    2017-09-01

    Regularized equations of motion can improve numerical integration for the propagation of orbits, and simplify the treatment of mission design problems. This monograph discusses standard techniques and recent research in the area. While each scheme is derived analytically, its accuracy is investigated numerically. Algebraic and topological aspects of the formulations are studied, as well as their application to practical scenarios such as spacecraft relative motion and new low-thrust trajectories.

  2. Regular black hole in three dimensions

    OpenAIRE

    Myung, Yun Soo; Yoon, Myungseok

    2008-01-01

    We find a new black hole in three dimensional anti-de Sitter space by introducing an anisotropic perfect fluid inspired by the noncommutative black hole. This is a regular black hole with two horizons. We compare thermodynamics of this black hole with that of non-rotating BTZ black hole. The first-law of thermodynamics is not compatible with the Bekenstein-Hawking entropy.

  3. On bigraded regularities of Rees algebra

    Indian Academy of Sciences (India)

    For any homogeneous ideal I in K [ x 1 , . . . , x n ] of analytic spread ℓ , we show that for the Rees algebra R ( I ) , r e g ( 0 , 1 ) s y z \\sl ( R ( I ) ) = r e g ( 0 , 1 ) T \\sl ( R ( I ) ) . We compute a formula for the (0, 1)-regularity of R ( I ) , which is a bigraded analog of Theorem1.1 of Aramova and Herzog ( A m . J . M a t h . 122 ( 4 ) ...

  4. Preconditioners for regularized saddle point matrices

    Czech Academy of Sciences Publication Activity Database

    Axelsson, Owe

    2011-01-01

    Roč. 19, č. 2 (2011), s. 91-112 ISSN 1570-2820 Institutional research plan: CEZ:AV0Z30860518 Keywords : saddle point matrices * preconditioning * regularization * eigenvalue clustering Subject RIV: BA - General Mathematics Impact factor: 0.533, year: 2011 http://www.degruyter.com/view/j/jnma.2011.19.issue-2/jnum.2011.005/jnum.2011.005. xml

  5. A short proof of increased parabolic regularity

    Directory of Open Access Journals (Sweden)

    Stephen Pankavich

    2015-08-01

    Full Text Available We present a short proof of the increased regularity obtained by solutions to uniformly parabolic partial differential equations. Though this setting is fairly introductory, our new method of proof, which uses a priori estimates and an inductive method, can be extended to prove analogous results for problems with time-dependent coefficients, advection-diffusion or reaction diffusion equations, and nonlinear PDEs even when other tools, such as semigroup methods or the use of explicit fundamental solutions, are unavailable.

  6. Regularity bounds on Zakharov system evolutions

    Directory of Open Access Journals (Sweden)

    James Colliander

    2002-08-01

    Full Text Available Spatial regularity properties of certain global-in-time solutions of the Zakharov system are established. In particular, the evolving solution $u(t$ is shown to satisfy an estimate $|u(t|_{H^s} leq C |t|^{(s-1+}$, where $H^s$ is the standard spatial Sobolev norm. The proof is an adaptation of earlier work on the nonlinear Schrodinger equation which reduces matters to bilinear estimates.

  7. Regularization in global sound equalization based on effort variation

    DEFF Research Database (Denmark)

    Stefanakis, Nick; Sarris, John; Jacobsen, Finn

    2009-01-01

    Sound equalization in closed spaces can be significantly improved by generating propagating waves that are naturally associated with the geometry, as, for example, plane waves in rectangular enclosures. This paper presents a control approach termed effort variation regularization based on this idea....... Effort variation equalization involves modifying the conventional cost function in sound equalization, which is based on minimizing least-squares reproduction errors, by adding a term that is proportional to the squared deviations between complex source strengths, calculated independently for the sources...

  8. The Analytical Description of Regular LDPC Codes Correcting Ability

    Directory of Open Access Journals (Sweden)

    Uryvsky Leonid

    2014-09-01

    Full Text Available The analytical description of regular LDPC (Low-Density Parity Check codes correcting ability has been investigated. The statistical dependencies for the maximum number of corrected bits per the code word as a function of LDPC code word length and code rate are given based on multiple experimental analyses of LDPC check matrices. The analytical expressions are proposed for the cases of linear, exponential and polynomial approximations of given results. The most exact analytical formula is proved by criterion of the minimum divergence between the experimental and theoretical results.

  9. Automatic detection of regularly repeating vocalizations

    Science.gov (United States)

    Mellinger, David

    2005-09-01

    Many animal species produce repetitive sounds at regular intervals. This regularity can be used for automatic recognition of the sounds, providing improved detection at a given signal-to-noise ratio. Here, the detection of sperm whale sounds is examined. Sperm whales produce highly repetitive ``regular clicks'' at periods of about 0.2-2 s, and faster click trains in certain behavioral contexts. The following detection procedure was tested: a spectrogram was computed; values within a certain frequency band were summed; time windowing was applied; each windowed segment was autocorrelated; and the maximum of the autocorrelation within a certain periodicity range was chosen. This procedure was tested on sets of recordings containing sperm whale sounds and interfering sounds, both low-frequency recordings from autonomous hydrophones and high-frequency ones from towed hydrophone arrays. An optimization procedure iteratively varies detection parameters (spectrogram frame length and frequency range, window length, periodicity range, etc.). Performance of various sets of parameters was measured by setting a standard level of allowable missed calls, and the resulting optimium parameters are described. Performance is also compared to that of a neural network trained using the data sets. The method is also demonstrated for sounds of blue whales, minke whales, and seismic airguns. [Funding from ONR.

  10. Identification of cyclic nucleotide gated channels using regular expressions

    KAUST Repository

    Zelman, Alice K.

    2013-09-03

    Cyclic nucleotide-gated channels (CNGCs) are nonselective cation channels found in plants, animals, and some bacteria. They have a six-transmembrane/one- pore structure, a cytosolic cyclic nucleotide-binding domain, and a cytosolic calmodulin-binding domain. Despite their functional similarities, the plant CNGC family members appear to have different conserved amino acid motifs within corresponding functional domains than animal and bacterial CNGCs do. Here we describe the development and application of methods employing plant CNGC-specific sequence motifs as diagnostic tools to identify novel candidate channels in different plants. These methods are used to evaluate the validity of annotations of putative orthologs of CNGCs from plant genomes. The methods detail how to employ regular expressions of conserved amino acids in functional domains of annotated CNGCs and together with Web tools such as PHI-BLAST and ScanProsite to identify novel candidate CNGCs in species including Physcomitrella patens. © Springer Science+Business Media New York 2013.

  11. Inversion of seismic arrival times with erratic noise using robust Tikhonov-TV regularization

    Science.gov (United States)

    Alrajawi, M.; Siahkoohi, H. R.; Gholami, A.

    2017-11-01

    A variety of methods have been presented to invert arrival times of seismic waves for velocity distribution. In real world, the velocity distribution models are piecewise smooth and consist of blocky structures as well as smooth varying parts. In such cases, implementation of Tikhonov regularization alone will recover the smooth varying parts of the velocity model, while the total variation (TV) regularization only is capable of recovering the blocky varying parts of the velocity model. In previous studies, combination of Tikhonov and TV regularizations (hereafter called classic Tikhonov-TV regularization) was used as a remedy for solving such inverse problems. In this study, we propose a method to minimize a cost function which of both Tikhonov and TV regularizations. The method is capable of suppressing undesired effects of the erratic noises and recovering both blocky and smooth varying parts of the model. An iteratively reweighted least-squares technique is used as a fast and efficient algorithm for minimization of the cost function. To demonstrate the effectiveness of the method, it is tested on both synthetic and real vertical seismic profiling arrival times as well as on a synthetic and real cross well arrival times. The proposed robust Tikhonov-TV method estimates better velocity model as compared to the robust Tikhonov and robust TV regularization methods. According to the results, the proposed hybrid method efficiently eliminates the individual weaknesses of constituent regularization methods.

  12. Efeito do vinho tinto associado ao exercício físico no sistema cardiovascular de ratos espontaneamente hipertensos

    OpenAIRE

    Soares Filho, Paulo Roberto; Castro, Iran; Stahlschmidt, Adriene

    2011-01-01

    FUNDAMENTO: Prática de exercício físico (EF) é eficiente no tratamento e na prevenção da hipertensão, associada à melhora do perfil lipídico e da função contrátil cardíaca. Consumo moderado e regular de bebidas alcoólicas, como vinho tinto, desempenha efeito cardiovascular protetor. Polifenóis da bebida apresentam propriedades antioxidantes, beneficiando vasos sanguíneos. Há poucas evidências sobre o consumo de vinho tinto associado ao EF e as influências no sistema cardiovascular. OBJETIVO: ...

  13. Construction Method of Regularization by Singular Value Decomposition of Design Matrix

    Directory of Open Access Journals (Sweden)

    LIN Dongfang

    2016-08-01

    Full Text Available Tikhonov regularization introduces regularization parameter and stable functional to improve the ill-condition. When the stable functional expressed as two-norm constraint, the regularization method is the same as ridge estimation. The analysis of the variance and bias of the ridge estimation shows that ridge estimation improved the ill-condition but introduced more bias. The estimation reliability is lowered. We get that correct the larger singular values cannot decrease the variance effectively but introduced more bias, correcting the smaller singular values can decrease the variance effectively. We choose the eigenvectors of the smaller singular values to construct the regularization matrix. It can adjust the correction of the singular values, decrease the variance and biases and finally get a more reliable estimation.

  14. Regular-, irregular-, and pseudo-character processing in Chinese: The regularity effect in normal adult readers

    Directory of Open Access Journals (Sweden)

    Dustin Kai Yan Lau

    2014-03-01

    Full Text Available Background Unlike alphabetic languages, Chinese uses a logographic script. However, the pronunciation of many character’s phonetic radical has the same pronunciation as the character as a whole. These are considered regular characters and can be read through a lexical non-semantic route (Weekes & Chen, 1999. Pseudocharacters are another way to study this non-semantic route. A pseudocharacter is the combination of existing semantic and phonetic radicals in their legal positions resulting in a non-existing character (Ho, Chan, Chung, Lee, & Tsang, 2007. Pseudocharacters can be pronounced by direct derivation from the sound of its phonetic radical. Conversely, if the pronunciation of a character does not follow that of the phonetic radical, it is considered as irregular and can only be correctly read through the lexical-semantic route. The aim of the current investigation was to examine reading aloud in normal adults. We hypothesized that the regularity effect, previously described for alphabetical scripts and acquired dyslexic patients of Chinese (Weekes & Chen, 1999; Wu, Liu, Sun, Chromik, & Zhang, 2014, would also be present in normal adult Chinese readers. Method Participants. Thirty (50% female native Hong Kong Cantonese speakers with a mean age of 19.6 years and a mean education of 12.9 years. Stimuli. Sixty regular-, 60 irregular-, and 60 pseudo-characters (with at least 75% of name agreement in Chinese were matched by initial phoneme, number of strokes and family size. Additionally, regular- and irregular-characters were matched by frequency (low and consistency. Procedure. Each participant was asked to read aloud the stimuli presented on a laptop using the DMDX software. The order of stimuli presentation was randomized. Data analysis. ANOVAs were carried out by participants and items with RTs and errors as dependent variables and type of stimuli (regular-, irregular- and pseudo-character as repeated measures (F1 or between subject

  15. Increasing stability and accuracy of the lattice Boltzmann scheme: recursivity and regularization

    OpenAIRE

    Malaspinas, Orestis

    2015-01-01

    In the present paper a lattice Boltzmann scheme is presented which exhibits an increased stability and accuracy with respect to standard single- or multi-relaxation-time (MRT) approaches. The scheme is based on a single-relaxation-time model where a special regularization procedure is applied. This regularization is based on the fact that, for a-thermal flows, there exists a recursive way to express the velocity distribution function at any order (in the Hermite series sense) in terms of the ...

  16. Efeitos da infertilidade no relacionamento dos cônjuges

    Directory of Open Access Journals (Sweden)

    Dieime Elaine Pereira de Faria

    2012-08-01

    Full Text Available Trata-se de um estudo sobre os efeitos da infertilidade no relacionamento dos cônjuges, com os objetivos de descrever o perfil da população de estudo e analisar os efeitos da infertilidade na vida emocional, sexual e conjugal. Para tal, foi realizado um estudo transversal e prospectivo em instituição especializada. A amostra foi constituída por 50 casais inférteis com seis anos de infertilidade em média. As mulheres manifestaram sentimentos negativos perante a infertilidade, enquanto os homens assumiram uma postura de suporte e apoio. Os efeitos na vida sexual foram mais expressivos nas mulheres, e o tratamento da infertilidade levou a mudanças positivas para ambos os cônjuges. Ao comparar os efeitos da infertilidade sobre os indivíduos que haviam realizado mais de um tratamento com aqueles no primeiro tratamento, observamos que não houve diferenças entre as mulheres; entre os homens houve diferenças no aspecto emocional (frustração e alívio e no relacionamento conjugal (fortalecimento e amadurecimento.

  17. Effects of the pneumoperitoneum in rats submitted to a unilateral nephrectomy: morphologic and functional study on the remnant kidney Efeitos do pneumoperitônio em ratos submetidos a nefrectomia unilateral: estudos morfológicos e funcionais no rim remanescente

    Directory of Open Access Journals (Sweden)

    Luiz Sergio Santos

    2005-06-01

    Full Text Available PURPOSE: The aim of this experimental study is to analyze the morphologic and functional effects of the pneumoperitoneum on the remnant kidney in rats submitted to a unilateral nephrectomy. METHODS: Forty-eight male adults Wistar rats , with an average weight between 240 to 350 g, were distributed in three groups. The rats in Group 1 were subdivided into two other subgroups: Control Group 1A and 1B. Groups 2 and 3 and respective subgroups included 12 rats each. All animals were anesthetized and submitted to a puncture. Animals in Groups 2 and 3 were submitted to abdominal insufflation with CO2, during 2 and 4 hours respectively, with a constant IAP of 15 mmHg. Rats of the Control Group 1A and 1B were maintained punctured during 2 and 4 hours respectively, however, without insufflation. In the end of this period, a left nephrectomy was performed in all animals. After 4 weeks, a new pneumoperitoneum with the same duration was installed, according to the groups. After 8 weeks, the animals were submitted to euthanasia to remove the remnant kidney. Samples of blood were collected during the whole experiment to evaluated the renal function by dosing serum creatinine. The remnant kidney was analyzed microscopically to evaluate its level of glomerular hypertrophy, the number of mesangial cells, and to observe the presence of glomerular sclerosis. All groups were kept under observation and the results were submitted to statistical analysis by a longitudinal and transversal comparative study. RESULTS: At the evaluation of residual renal function no significant clinical alteration was seen in rats submitted to pneumoperitoneum during 2 and 4 hours after a period of 8 weeks. The morphologic analysis of the remnant kidney showed no histological renal injury in the groups. CONCLUSION: The function and renal morphology of rats submitted to a unilateral nephrectomy were not significantly influenced by prolonged and successive pneumoperitoneum, according to this

  18. Comparison of Regularization Methods in Fluorescence Molecular Tomography

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    Dianwen Zhu

    2014-04-01

    Full Text Available In vivo fluorescence molecular tomography (FMT has been a popular functional imaging modality in research labs in the past two decades. One of the major difficulties of FMT lies in the ill-posed and ill-conditioned nature of the inverse problem in reconstructing the distribution of fluorophores inside objects. The popular regularization methods based on L2, L1 and total variation (TV norms have been applied in FMT reconstructions. The non-convex Lq(0 < q < 1 semi-norm and Log function have also been studied recently. In this paper, we adopt a uniform optimization transfer framework for these regularization methods in FMT and compare their individual, as well as the combined effects on both small, localized targets, such as tumors in the early stage, and large targets, such as liver. Numerical simulation studies and phantom experiments have been carried out, and we found that Lq with q near 1/2 performs the best in reconstructing small targets, while joint L2 and Log performs the best for large targets.

  19. Statistical regularities in the rank-citation profile of scientists

    CERN Document Server

    Petersen, Alexander M; Succi, Sauro

    2011-01-01

    Recent "science of science" research shows common regularities in the publication patterns of scientific papers across time and discipline. Here we analyze the complete publication careers of 300 scientists and find remarkable regularity in the functional form of the rank-citation profile c_{i}(r) for each scientist i =1...300. We find that the rank-ordered citation distribution c_{i}(r) can be approximated by a discrete generalized beta distribution (DGBD) over the entire range of ranks r, which allows for the characterization and comparison of c_{i}(r) using a common framework. The functional form of the DGBD has two scaling exponents, beta_i and gamma_i, which determine the scaling behavior of c_{i}(r) for both small and large rank r. The crossover between two scaling regimes suggests a complex reinforcement or positive-feedback relation between the impact of a scientist's most famous papers and the impact of his/her other papers. Moreover, since two scientists with equivalent Hirsch h-index values may hav...

  20. O efeito da atividade física no aparelho locomotor do idoso The effect of physical training on locomotive apparatus in elderly people

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    André Pedrinelli

    2009-04-01

    Full Text Available Alterações fisiológicas que ocorrem no aparellho locomotor devido ao envelhecimento como perda de massa muscular, perda do equilíbrio corporal, diminuição da massa óssea e osteoartrose causam limitações às atividade da vida diária do idoso, comprometendo sua qualidade de vida e o tornando mais frágil e dependente. Idosos que realizam atividade física periodicamente tem melhor independência funcional e melhor qualidade de vida do que aquele sedentário. Esse artigo aborda as principais alterações fisiológica do processo de envelhecimento e realiza uma revisão da literatura atual sobre os efeitos que o exercício físico causa no aparelho locomotor do idoso, especificando qual a melhor forma de prescrever atividade física nessa faixa etária.Physiological changes taking place on the locomotive apparatus as a result of aging, such as muscular mass loss, body balance loss, reduced bone mass and osteoarthrosis cause limitations to the daily activities of elderly people, compromising their quality of life and making them weaker and dependent. Aged people who regularly practice physical activities have a higher level of functional independence and a better quality of life than the sedentary ones. This article addresses the key physiological changes with aging and provides a review of current literature about the effects of physical exercises on the locomotive apparatus of elderly individuals, specifying the best ways to prescribe physical exercises to this age group.

  1. Two-pass greedy regular expression parsing

    DEFF Research Database (Denmark)

    Grathwohl, Niels Bjørn Bugge; Henglein, Fritz; Nielsen, Lasse

    2013-01-01

    We present new algorithms for producing greedy parses for regular expressions (REs) in a semi-streaming fashion. Our lean-log algorithm executes in time O(mn) for REs of size m and input strings of size n and outputs a compact bit-coded parse tree representation. It improves on previous algorithms...... by: operating in only 2 passes; using only O(m) words of random-access memory (independent of n); requiring only kn bits of sequentially written and read log storage, where k

  2. Multichannel image regularization using anisotropic geodesic filtering

    Energy Technology Data Exchange (ETDEWEB)

    Grazzini, Jacopo A [Los Alamos National Laboratory

    2010-01-01

    This paper extends a recent image-dependent regularization approach introduced in aiming at edge-preserving smoothing. For that purpose, geodesic distances equipped with a Riemannian metric need to be estimated in local neighbourhoods. By deriving an appropriate metric from the gradient structure tensor, the associated geodesic paths are constrained to follow salient features in images. Following, we design a generalized anisotropic geodesic filter; incorporating not only a measure of the edge strength, like in the original method, but also further directional information about the image structures. The proposed filter is particularly efficient at smoothing heterogeneous areas while preserving relevant structures in multichannel images.

  3. Regular and Chaotic Dynamics of Flexible Plates

    Directory of Open Access Journals (Sweden)

    J. Awrejcewicz

    2014-01-01

    Full Text Available Nonlinear dynamics of flexible rectangular plates subjected to the action of longitudinal and time periodic load distributed on the plate perimeter is investigated. Applying both the classical Fourier and wavelet analysis we illustrate three different Feigenbaum type scenarios of transition from a regular to chaotic dynamics. We show that the system vibrations change with respect not only to the change of control parameters, but also to all fixed parameters (system dynamics changes when the independent variable, time, increases. In addition, we show that chaotic dynamics may appear also after the second Hopf bifurcation. Curves of equal deflections (isoclines lose their previous symmetry while transiting into chaotic vibrations.

  4. Equivariant semidefinite lifts of regular polygons

    OpenAIRE

    Fawzi, Hamza; Saunderson, James; Parrilo, Pablo A.

    2014-01-01

    Given a polytope P in $\\mathbb{R}^n$, we say that P has a positive semidefinite lift (psd lift) of size d if one can express P as the linear projection of an affine slice of the positive semidefinite cone $\\mathbf{S}^d_+$. If a polytope P has symmetry, we can consider equivariant psd lifts, i.e. those psd lifts that respect the symmetry of P. One of the simplest families of polytopes with interesting symmetries are regular polygons in the plane, which have played an important role in the stud...

  5. Equivariant semidefinite lifts of regular polygons

    OpenAIRE

    Fawzi, Hamza; Saunderson, J.; Parrilo, PA

    2017-01-01

    Given a polytope P in $\\mathbb{R}^n$, we say that P has a positive semidefinite lift (psd lift) of size d if one can express P as the linear projection of an affine slice of the positive semidefinite cone $\\mathbf{S}^d_+$. If a polytope P has symmetry, we can consider equivariant psd lifts, i.e. those psd lifts that respect the symmetry of P. One of the simplest families of polytopes with interesting symmetries are regular polygons in the plane, which have played an importan...

  6. Foaming behaviour of organic and regular milk

    OpenAIRE

    Pijnenburg, J.; Sala, G.; Valenberg, van, H.J.F.; Meinders, M.B.J.

    2012-01-01

    Organic milk is used more and more by consumers to froth milk that is used e.g. for the preparation of a capuccino. Frequently, organic milk turns out not to foam properly. This report describes a study to find the main couse of this bad foamability of organic milk. The focus of the research was to get insight in the foaming behaviour of a specific brand, indicated as A. The foamability and stability of different milk, both organic and regular, as well as skimmed, semi-skimmed, and full fat, ...

  7. Wave regularity in curve integrable spacetimes

    CERN Document Server

    Sanchez, Yafet Sanchez

    2015-01-01

    The idea of defining a gravitational singularity as an obstruction to the dynamical evolution of a test field (described by a PDE) rather than the dynamical evolution of a particle (described by a geodesics) is explored. In particular, the concept of wave regularity is introduced which serves to show that the classical singularities in curve integrable spacetimes do not interrupt the well-posedness of the wave equation. The techniques used also provide arguments that can be extended to establish when a classically singular spacetime remains singular in a semi-classical picture.

  8. Electronic Structure of Regular Bacterial Surface Layers

    Science.gov (United States)

    Vyalikh, Denis V.; Danzenbächer, Steffen; Mertig, Michael; Kirchner, Alexander; Pompe, Wolfgang; Dedkov, Yuriy S.; Molodtsov, Serguei L.

    2004-12-01

    We report photoemission and near-edge x-ray absorption fine structure measurements of the occupied and unoccupied valence electronic states of the regular surface layer of Bacillus sphaericus, which is widely used as the protein template for the fabrication of metallic nanostructures. The two-dimensional protein crystal shows a semiconductorlike behavior with a gap value of ˜3.0 eV and the Fermi energy close to the bottom of the lowest unoccupied molecular orbital. We anticipate that these results will open up new possibilities for the electric addressability of biotemplated low-dimensional hybrid structures.

  9. Strategies for regular segmented reductions on GPU

    DEFF Research Database (Denmark)

    Larsen, Rasmus Wriedt; Henriksen, Troels

    2017-01-01

    We present and evaluate an implementation technique for regular segmented reductions on GPUs. Existing techniques tend to be either consistent in performance but relatively inefficient in absolute terms, or optimised for specific workloads and thereby exhibiting bad performance for certain input...... is in the context of the Futhark compiler, the implementation technique is applicable to any library or language that has a need for segmented reductions. We evaluate the technique on four microbenchmarks, two of which we also compare to implementations in the CUB library for GPU programming, as well as on two...

  10. Os efeitos do ultra-som terapêutico nas lesões por esmagamento do nervo ciático de ratos: análise funcional da marcha Effects of therapeutic ultrasound on injuries due to crushing of the sciatic nerve in rats: functional evaluation of gait

    Directory of Open Access Journals (Sweden)

    VV Monte-Raso

    2006-01-01

    Full Text Available INTRODUÇÃO: Os efeitos da irradiação ultra-sônica terapêutica na regeneração de nervos periféricos não são ainda bem conhecidos, particularmente no que se refere à recuperação funcional. Por outro lado, o método da avaliação da impressão da pegada do rato para medida do Índice Funcional do Ciático (IFC já está bem sistematizado, mostrando estreita correlação com a regeneração morfológica do nervo ciático lesado em ratos. Objetivos: Analisar a influência do ultra-som terapêutico na regeneração do nervo ciático de ratos submetido a esmagamento controlado. Material e métodos: Foram empregados 20 ratos da linhagem Wistar com peso corporal médio de 300 g, divididos em dois grupos conforme o tipo de procedimento realizado: 1 somente esmagamento (n=10; 2 esmagamento e irradiação com ultra-som (n=10. Sob anestesia geral, o nervo ciático era exposto na coxa direita do animal e esmagado com um dispositivo especialmente confeccionado para essa finalidade, com uma carga fixa de 15 Kg por 10 minutos, num segmento de 5 mm proximal à sua bifurcação. A irradiação ultra-sônica pulsada de baixa intensidade (1:5, 0,4 W/cm², 1 MHz, duração 2 minutos era iniciada já no primeiro dia pós-operatório e realizada por dez dias consecutivos. As impressões das pegadas dos animais, obtidas semanalmente, da primeira à terceira semana pós-operatória, em passarela específica para essa finalidade, foram avaliadas por meio de um programa de computador igualmente específico, segundo método pré-existente já testado em trabalhos anteriores, com cálculo automático do IFC. Resultados: O IFC aumentou progressivamente nos dois grupos, passando no Grupo 2 de 101 na primeira semana, para 59,21 na segunda e 26,68 na terceira, o que significou uma melhora de 73% entre a primeira e a última medida. No Grupo 1, o IFC subiu de 98,2 na primeira semana, para 79,5 na segunda e 44 na terceira, o que significou uma melhora de 55% entre a

  11. Regularized Primal-Dual Subgradient Method for Distributed Constrained Optimization.

    Science.gov (United States)

    Yuan, Deming; Ho, Daniel W C; Xu, Shengyuan

    2016-09-01

    In this paper, we study the distributed constrained optimization problem where the objective function is the sum of local convex cost functions of distributed nodes in a network, subject to a global inequality constraint. To solve this problem, we propose a consensus-based distributed regularized primal-dual subgradient method. In contrast to the existing methods, most of which require projecting the estimates onto the constraint set at every iteration, only one projection at the last iteration is needed for our proposed method. We establish the convergence of the method by showing that it achieves an O ( K (-1/4) ) convergence rate for general distributed constrained optimization, where K is the iteration counter. Finally, a numerical example is provided to validate the convergence of the propose method.

  12. Simulating thimble regularization of lattice quantum field theories

    CERN Document Server

    Di Renzo, Francesco

    2016-01-01

    Monte Carlo simulations of lattice quantum field theories on Lefschetz thimbles are non trivial. We discuss a new Monte Carlo algorithm based on the idea of computing contributions to the functional integral which come from complete flow lines. The latter are the steepest ascent paths attached to critical points, i.e. the basic building blocks of thimbles. The measure to sample is thus dictated by the contribution of complete flow lines to the partition function. The algorithm is based on a heat bath sampling of the gaussian approximation of the thimble: this defines the proposals for a Metropolis-like accept/reject step. The effectiveness of the algorithm has been tested on a few models, e.g. the chiral random matrix model. We also discuss thimble regularization of gauge theories, and in particular the successfull application to 0+1 dimensional QCD and the status and prospects for Yang-Mills theories.

  13. Harmonic R Matrices for Scattering Amplitudes and Spectral Regularization

    Science.gov (United States)

    Ferro, Livia; Łukowski, Tomasz; Meneghelli, Carlo; Plefka, Jan; Staudacher, Matthias

    2013-03-01

    Planar N=4 supersymmetric Yang-Mills theory appears to be integrable. While this allows one to find this theory’s exact spectrum, integrability has hitherto been of no direct use for scattering amplitudes. To remedy this, we deform all scattering amplitudes by a spectral parameter. The deformed tree-level four-point function turns out to be essentially the one-loop R matrix of the integrable N=4 spin chain satisfying the Yang-Baxter equation. Deformed on-shell three-point functions yield novel three-leg R matrices satisfying bootstrap equations. Finally, we supply initial evidence that the spectral parameter might find its use as a novel symmetry-respecting regulator replacing dimensional regularization. Its physical meaning is a local deformation of particle helicity, a fact which might be useful for a much larger class of nonintegrable four-dimensional field theories.

  14. Regularization Reconstruction Method for Imaging Problems in Electrical Capacitance Tomography

    Science.gov (United States)

    Chu, Pan; Lei, Jing

    2017-11-01

    The electrical capacitance tomography (ECT) is deemed to be a powerful visualization measurement technique for the parametric measurement in a multiphase flow system. The inversion task in the ECT technology is an ill-posed inverse problem, and seeking for an efficient numerical method to improve the precision of the reconstruction images is important for practical measurements. By the introduction of the Tikhonov regularization (TR) methodology, in this paper a loss function that emphasizes the robustness of the estimation and the low rank property of the imaging targets is put forward to convert the solution of the inverse problem in the ECT reconstruction task into a minimization problem. Inspired by the split Bregman (SB) algorithm, an iteration scheme is developed for solving the proposed loss function. Numerical experiment results validate that the proposed inversion method not only reconstructs the fine structures of the imaging targets, but also improves the robustness.

  15. Supporting Regularized Logistic Regression Privately and Efficiently.

    Science.gov (United States)

    Li, Wenfa; Liu, Hongzhe; Yang, Peng; Xie, Wei

    2016-01-01

    As one of the most popular statistical and machine learning models, logistic regression with regularization has found wide adoption in biomedicine, social sciences, information technology, and so on. These domains often involve data of human subjects that are contingent upon strict privacy regulations. Concerns over data privacy make it increasingly difficult to coordinate and conduct large-scale collaborative studies, which typically rely on cross-institution data sharing and joint analysis. Our work here focuses on safeguarding regularized logistic regression, a widely-used statistical model while at the same time has not been investigated from a data security and privacy perspective. We consider a common use scenario of multi-institution collaborative studies, such as in the form of research consortia or networks as widely seen in genetics, epidemiology, social sciences, etc. To make our privacy-enhancing solution practical, we demonstrate a non-conventional and computationally efficient method leveraging distributing computing and strong cryptography to provide comprehensive protection over individual-level and summary data. Extensive empirical evaluations on several studies validate the privacy guarantee, efficiency and scalability of our proposal. We also discuss the practical implications of our solution for large-scale studies and applications from various disciplines, including genetic and biomedical studies, smart grid, network analysis, etc.

  16. Supporting Regularized Logistic Regression Privately and Efficiently.

    Directory of Open Access Journals (Sweden)

    Wenfa Li

    Full Text Available As one of the most popular statistical and machine learning models, logistic regression with regularization has found wide adoption in biomedicine, social sciences, information technology, and so on. These domains often involve data of human subjects that are contingent upon strict privacy regulations. Concerns over data privacy make it increasingly difficult to coordinate and conduct large-scale collaborative studies, which typically rely on cross-institution data sharing and joint analysis. Our work here focuses on safeguarding regularized logistic regression, a widely-used statistical model while at the same time has not been investigated from a data security and privacy perspective. We consider a common use scenario of multi-institution collaborative studies, such as in the form of research consortia or networks as widely seen in genetics, epidemiology, social sciences, etc. To make our privacy-enhancing solution practical, we demonstrate a non-conventional and computationally efficient method leveraging distributing computing and strong cryptography to provide comprehensive protection over individual-level and summary data. Extensive empirical evaluations on several studies validate the privacy guarantee, efficiency and scalability of our proposal. We also discuss the practical implications of our solution for large-scale studies and applications from various disciplines, including genetic and biomedical studies, smart grid, network analysis, etc.

  17. Maze navigation by honeybees: learning path regularity.

    Science.gov (United States)

    Zhang, S; Mizutani, A; Srinivasan, M V

    2000-01-01

    We investigated the ability of honeybees to learn mazes of four types: constant-turn mazes, in which the appropriate turn is always in the same direction in each decision chamber; zig-zag mazes, in which the appropriate turn is alternately left and right in successive decision chambers; irregular mazes, in which there is no readily apparent pattern to the turns; and variable irregular mazes, in which the bees were trained to learn several irregular mazes simultaneously. The bees were able to learn to navigate all four types of maze. Performance was best in the constant-turn mazes, somewhat poorer in the zig-zag mazes, poorer still in the irregular mazes, and poorest in the variable irregular mazes. These results demonstrate that bees do not navigate such mazes simply by memorizing the entire sequence of appropriate turns. Rather, performance in the various configurations depends on the existence of regularity in the structure of the maze and on the ease with which this regularity is recognized and learned.

  18. Handicap Labelings of 4-Regular Graphs

    Directory of Open Access Journals (Sweden)

    Petr Kovar

    2017-01-01

    Full Text Available Let G be a simple graph, let f : V(G→{1,2,...,|V(G|} be a bijective mapping. The weight of v ∈ V(G is the sum of labels of all vertices adjacent to v. We say that f is a distance magic labeling of G if the weight of every vertex is the same constant k and we say that f is a handicap magic labeling of G if the weight of every vertex v is l + f(v for some constant l. Graphs that allow such labelings are called distance magic or handicap, respectively. Distance magic and handicap labelings of regular graphs are used for scheduling incomplete tournaments. While distance magic labelings correspond to so called equalized tournaments, handicap labelings can be used to schedule incomplete tournaments that are more challenging to stronger teams or players, hence they increase competition and yield attractive schemes in which every games counts. We summarize known results on distance magic and handicap labelings and construct a new infinite class of 4-regular handicap graphs.

  19. From Regular to Strictly Locally Testable Languages

    Directory of Open Access Journals (Sweden)

    Stefano Crespi Reghizzi

    2011-08-01

    Full Text Available A classical result (often credited to Y. Medvedev states that every language recognized by a finite automaton is the homomorphic image of a local language, over a much larger so-called local alphabet, namely the alphabet of the edges of the transition graph. Local languages are characterized by the value k=2 of the sliding window width in the McNaughton and Papert's infinite hierarchy of strictly locally testable languages (k-slt. We generalize Medvedev's result in a new direction, studying the relationship between the width and the alphabetic ratio telling how much larger the local alphabet is. We prove that every regular language is the image of a k-slt language on an alphabet of doubled size, where the width logarithmically depends on the automaton size, and we exhibit regular languages for which any smaller alphabetic ratio is insufficient. More generally, we express the trade-off between alphabetic ratio and width as a mathematical relation derived from a careful encoding of the states. At last we mention some directions for theoretical development and application.

  20. Words cluster phonetically beyond phonotactic regularities.

    Science.gov (United States)

    Dautriche, Isabelle; Mahowald, Kyle; Gibson, Edward; Christophe, Anne; Piantadosi, Steven T

    2017-06-01

    Recent evidence suggests that cognitive pressures associated with language acquisition and use could affect the organization of the lexicon. On one hand, consistent with noisy channel models of language (e.g., Levy, 2008), the phonological distance between wordforms should be maximized to avoid perceptual confusability (a pressure for dispersion). On the other hand, a lexicon with high phonological regularity would be simpler to learn, remember and produce (e.g., Monaghan et al., 2011) (a pressure for clumpiness). Here we investigate wordform similarity in the lexicon, using measures of word distance (e.g., phonological neighborhood density) to ask whether there is evidence for dispersion or clumpiness of wordforms in the lexicon. We develop a novel method to compare lexicons to phonotactically-controlled baselines that provide a null hypothesis for how clumpy or sparse wordforms would be as the result of only phonotactics. Results for four languages, Dutch, English, German and French, show that the space of monomorphemic wordforms is clumpier than what would be expected by the best chance model according to a wide variety of measures: minimal pairs, average Levenshtein distance and several network properties. This suggests a fundamental drive for regularity in the lexicon that conflicts with the pressure for words to be as phonologically distinct as possible. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. The Existence of Quasi Regular and Bi-Regular Self-Complementary 3-Uniform Hypergraphs

    Directory of Open Access Journals (Sweden)

    Kamble Lata N.

    2016-05-01

    Full Text Available A k-uniform hypergraph H = (V ;E is called self-complementary if there is a permutation σ : V → V , called a complementing permutation, such that for every k-subset e of V , e ∈ E if and only if σ(e ∉ E. In other words, H is isomorphic with H′ = (V ; V(k − E. In this paper we define a bi-regular hypergraph and prove that there exists a bi-regular self-complementary 3-uniform hypergraph on n vertices if and only if n is congruent to 0 or 2 modulo 4. We also prove that there exists a quasi regular self-complementary 3-uniform hypergraph on n vertices if and only if n is congruent to 0 modulo 4.

  2. Bioprocess data mining using regularized regression and random forests.

    Science.gov (United States)

    Hassan, Syeda; Farhan, Muhammad; Mangayil, Rahul; Huttunen, Heikki; Aho, Tommi

    2013-01-01

    In bioprocess development, the needs of data analysis include (1) getting overview to existing data sets, (2) identifying primary control parameters, (3) determining a useful control direction, and (4) planning future experiments. In particular, the integration of multiple data sets causes that these needs cannot be properly addressed by regression models that assume linear input-output relationship or unimodality of the response function. Regularized regression and random forests, on the other hand, have several properties that may appear important in this context. They are capable, e.g., in handling small number of samples with respect to the number of variables, feature selection, and the visualization of response surfaces in order to present the prediction results in an illustrative way. In this work, the applicability of regularized regression (Lasso) and random forests (RF) in bioprocess data mining was examined, and their performance was benchmarked against multiple linear regression. As an example, we used data from a culture media optimization study for microbial hydrogen production. All the three methods were capable in providing a significant model when the five variables of the culture media optimization were linearly included in modeling. However, multiple linear regression failed when also the multiplications and squares of the variables were included in modeling. In this case, the modeling was still successful with Lasso (correlation between the observed and predicted yield was 0.69) and RF (0.91). We found that both regularized regression and random forests were able to produce feasible models, and the latter was efficient in capturing the non-linearity in the data. In this kind of a data mining task of bioprocess data, both methods outperform multiple linear regression.

  3. Efeito do exercício associado ao transplante de células-tronco sobre a função ventricular de ratos pós-infarto agudo do miocárdio Effect of exercise associated with stem cell transplantation on ventricular function in rats after acute myocardial infarction

    Directory of Open Access Journals (Sweden)

    Simone Cosmo

    2012-12-01

    Full Text Available OBJETIVO: Avaliar o efeito da associação terapêutica entre o transplante autólogo de células-tronco e o exercício físico aquático, sobre a fração de ejeção do ventrículo esquerdo (FEVE de ratos com disfunção ventricular pós-infarto agudo do miocárdio (IAM. MÉTODOS: Foram induzidos ao IAM, por ligadura da artéria coronária esquerda, 21 ratos Wistar. Os animais foram submetidos à ecocardiografia para avaliação da FEVE (% e dos volumes diastólico e sistólico finais do ventrículo esquerdo (VDF, VSF, ml, randomizados e ao transplante das células-tronco mononucleares. Os animais foram divididos em quatro grupos: grupo sedentário sem células (n=5, sedentário com células (n=5, treinado sem células (n=5 e treinado com células (n=6. O treinamento físico foi iniciado 30 dias após o IAM e realizado em piscina adaptada durante 30 dias. No início e no final do protocolo de treinamento físico, foram realizadas dosagens de lactato. Os animais foram submetidos a nova ecocardiografia após 60 dias do IAM. RESULTADOS: Comparação dos valores de FEVE 30 dias e 60 dias pós-IAM, respectivamente: sedentário sem (35,20 ± 7,64% vs. 22,39 ± 4,56% P=0,026, com células (25,18 ± 7,73% vs. 23,85 ± 9,51% P=0,860 e no treinado sem (21,49 ± 2,70% vs. 20,71 ± 7,14% P=0,792, treinado com células (28,86 ± 6,68 vs. 38,43 ±7,56% P=0,062. Identificou-se a diminuição de fibras colágenas, nas regiões de fibrose miocárdica no grupo treinado com e sem células. CONCLUSÃO: A associação terapêutica entre exercício físico e o transplante autólogo de células-tronco foi benéfica contra as ações do remodelamento ventricular.OBJECTIVE: To analyze the functional and anatomical-pathological effect of transplantation of bone marrow mononuclear cells associated to aquatic physical activity after myocardial infarction in rats. METHODS: Twenty-one rats were induced by myocardial infarction, through left coronary artery ligation. After

  4. Efeitos da poluição do ar na função respiratória de escolares, Rio de Janeiro, RJ Efectos de la polución del aire en la función respiratoria de escolares, Rio de Janeiro, Sureste de Brasil Effect of air pollution on lung function in schoolchildren in Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Hermano Albuquerque de Castro

    2009-02-01

    Full Text Available OBJETIVO: Analisar a associação entre exposição diária à poluição do ar e função respiratória de escolares. MÉTODOS: Estudo de painel com uma amostra aleatória de 118 escolares (seis a 15 anos de idade da rede pública do Rio de Janeiro (RJ, residentes até 2 km do local do estudo. Dados sobre características das crianças foram obtidos por questionário, incluindo o International Study of Asthma and Allergies in Childhood. Exames diários de pico de fluxo foram realizados para medir a função respiratória. Dados diários dos níveis de PM10, SO2, O3, NO2 e CO, temperatura e umidade foram fornecidos por um monitor móvel. As medidas repetidas de função respiratória foram associadas aos níveis dos poluentes por meio de modelo multinível ajustado por tendência temporal, temperatura, umidade do ar, exposição domiciliar ao fumo, ser asmático, altura, sexo, peso e idade das crianças. RESULTADOS: O pico de fluxo expiratório médio foi 243,5 l/m (dp=58,9. A menor média do pico de fluxo expiratório foi 124 l/m e a maior 450 l/m. Para o aumento de 10 µg/m³ de PM10 houve uma diminuição de 0,34 l/min na média do pico de fluxo no terceiro dia. Para o aumento de 10 µg/m³ de NO2 houve uma diminuição entre 0,23 l/min a 0,28 l/min na média do pico de fluxo após a exposição. Os efeitos do CO e do SO2 no pico de fluxo dos escolares não foram estatisticamente significativos. O O3 apresentou um resultado protetor: o aumento de 10 µg/m³ de O3 estaria associado, um dia depois da exposição, a aumento de 0,2 l/min na média da função respiratória. CONCLUSÕES: Mesmo dentro de níveis aceitáveis na maior parte do período, a poluição atmosférica, principalmente o PM10 e o NO2, esteve associada à diminuição da função respiratória de crianças residentes no Rio de Janeiro.OBJETIVO: Analizar la asociación entre exposición diaria a la polución del aire y función respiratoria de escolares. MÉTODOS: Estudio de

  5. Evaluating the effect of Tikhonov regularization schemes on predictions in a variable‐density groundwater model

    Science.gov (United States)

    White, Jeremy T.; Langevin, Christian D.; Hughes, Joseph D.

    2010-01-01

    Calibration of highly‐parameterized numerical models typically requires explicit Tikhonovtype regularization to stabilize the inversion process. This regularization can take the form of a preferred parameter values scheme or preferred relations between parameters, such as the preferred equality scheme. The resulting parameter distributions calibrate the model to a user‐defined acceptable level of model‐to‐measurement misfit, and also minimize regularization penalties on the total objective function. To evaluate the potential impact of these two regularization schemes on model predictive ability, a dataset generated from a synthetic model was used to calibrate a highly-parameterized variable‐density SEAWAT model. The key prediction is the length of time a synthetic pumping well will produce potable water. A bi‐objective Pareto analysis was used to explicitly characterize the relation between two competing objective function components: measurement error and regularization error. Results of the Pareto analysis indicate that both types of regularization schemes affect the predictive ability of the calibrated model.

  6. A two-component Matched Interface and Boundary (MIB) regularization for charge singularity in implicit solvation

    Science.gov (United States)

    Geng, Weihua; Zhao, Shan

    2017-12-01

    We present a new Matched Interface and Boundary (MIB) regularization method for treating charge singularity in solvated biomolecules whose electrostatics are described by the Poisson-Boltzmann (PB) equation. In a regularization method, by decomposing the potential function into two or three components, the singular component can be analytically represented by the Green's function, while other components possess a higher regularity. Our new regularization combines the efficiency of two-component schemes with the accuracy of the three-component schemes. Based on this regularization, a new MIB finite difference algorithm is developed for solving both linear and nonlinear PB equations, where the nonlinearity is handled by using the inexact-Newton's method. Compared with the existing MIB PB solver based on a three-component regularization, the present algorithm is simpler to implement by circumventing the work to solve a boundary value Poisson equation inside the molecular interface and to compute related interface jump conditions numerically. Moreover, the new MIB algorithm becomes computationally less expensive, while maintains the same second order accuracy. This is numerically verified by calculating the electrostatic potential and solvation energy on the Kirkwood sphere on which the analytical solutions are available and on a series of proteins with various sizes.

  7. Orbital minimization method with ℓ1 regularization

    Science.gov (United States)

    Lu, Jianfeng; Thicke, Kyle

    2017-05-01

    We consider a modification of the orbital minimization method (OMM) energy functional which contains an ℓ1 penalty term in order to find a sparse representation of the low-lying eigenspace of self-adjoint operators. We analyze the local minima of the modified functional as well as the convergence of the modified functional to the original functional. Algorithms combining soft thresholding with gradient descent are proposed for minimizing this new functional. Numerical tests validate our approach. In addition, we also prove the unanticipated and remarkable property that every local minimum of the OMM functional without the ℓ1 term is also a global minimum.

  8. Bayesian Selection for the ℓ _2 -Potts Model Regularization Parameter: 1-D Piecewise Constant Signal Denoising

    Science.gov (United States)

    Frecon, Jordan; Pustelnik, Nelly; Dobigeon, Nicolas; Wendt, Herwig; Abry, Patrice

    2017-10-01

    Piecewise constant denoising can be solved either by deterministic optimization approaches, based on the Potts model, or by stochastic Bayesian procedures. The former lead to low computational time but require the selection of a regularization parameter, whose value significantly impacts the achieved solution, and whose automated selection remains an involved and challenging problem. Conversely, fully Bayesian formalisms encapsulate the regularization parameter selection into hierarchical models, at the price of high computational costs. This contribution proposes an operational strategy that combines hierarchical Bayesian and Potts model formulations, with the double aim of automatically tuning the regularization parameter and of maintaining computational effciency. The proposed procedure relies on formally connecting a Bayesian framework to a l2-Potts functional. Behaviors and performance for the proposed piecewise constant denoising and regularization parameter tuning techniques are studied qualitatively and assessed quantitatively, and shown to compare favorably against those of a fully Bayesian hierarchical procedure, both in accuracy and in computational load.

  9. Access to serviced land for the urban poor: the regularization paradox in Mexico

    Directory of Open Access Journals (Sweden)

    Alfonso Iracheta Cenecorta

    2000-01-01

    Full Text Available The insufficient supply of serviced land at affordable prices for the urban poor and the need for regularization of the consequent illegal occupations in urban areas are two of the most important issues on the Latin American land policy agenda. Taking a structural/integrated view on the functioning of the urban land market in Latin America, this paper discusses the nexus between the formal and the informal land markets. It thus exposes the perverse feedback effects that curative regularization policies may have on the process by which irregularity is produced in the first place. The paper suggests that a more effective approach to the provision of serviced land for the poor cannot be resolved within the prevailing (curative regularization programs. These programs should have the capacity to mobilize the resources that do exist into a comprehensive program that links regularization with fiscal policy, including the exploration of value capture mechanisms.

  10. Form factors and scattering amplitudes in N=4 SYM in dimensional and massive regularizations

    Energy Technology Data Exchange (ETDEWEB)

    Henn, Johannes M. [Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik; California Univ., Santa Barbara, CA (United States). Kavli Inst. for Theoretical Physics; Moch, Sven [California Univ., Santa Barbara, CA (United States). Kavli Inst. for Theoretical Physics; Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Naculich, Stephen G. [California Univ., Santa Barbara, CA (United States). Kavli Inst. for Theoretical Physics; Bowdoin College, Brunswick, ME (United States). Dept. of Physics

    2011-09-15

    The IR-divergent scattering amplitudes of N=4 supersymmetric Yang-Mills theory can be regulated in a variety of ways, including dimensional regularization and massive (or Higgs) regularization. The IR-finite part of an amplitude in different regularizations generally differs by an additive constant at each loop order, due to the ambiguity in separating finite and divergent contributions. We give a prescription for defining an unambiguous, regulator-independent finite part of the amplitude by factoring off a product of IR-divergent ''wedge'' functions. For the cases of dimensional regularization and the common-mass Higgs regulator, we define the wedge function in terms of a form factor, and demonstrate the regularization independence of the n-point amplitude through two loops. We also deduce the form of the wedge function for the more general differential-mass Higgs regulator, although we lack an explicit operator definition in this case. Finally, using extended dual conformal symmetry, we demonstrate the link between the differential-mass wedge function and the anomalous dual conformal Ward identity for the finite part of the scattering amplitude. (orig.)

  11. Thermodynamics of regular accelerating black holes

    Science.gov (United States)

    Astorino, Marco

    2017-03-01

    Using the covariant phase space formalism, we compute the conserved charges for a solution, describing an accelerating and electrically charged Reissner-Nordstrom black hole. The metric is regular provided that the acceleration is driven by an external electric field, in spite of the usual string of the standard C-metric. The Smarr formula and the first law of black hole thermodynamics are fulfilled. The resulting mass has the same form of the Christodoulou-Ruffini irreducible mass. On the basis of these results, we can extrapolate the mass and thermodynamics of the rotating C-metric, which describes a Kerr-Newman-(A)dS black hole accelerated by a pulling string.

  12. Generalized equations of state and regular universes

    CERN Document Server

    Contreras, Felipe; González, Esteban

    2015-01-01

    We found non singular solutions for universes filled with a fluid which obey a Generalized Equation of State of the form $P(\\rho)=-A\\rho+\\gamma\\rho^{\\lambda}$. An emergent universe is obtained if $A=1$ and $\\lambda =1/2$. If the matter source is reinterpret as that of a scalar matter field with some potential, the corresponding potential is derived. For a closed universe, an exact bounce solution is found for $A=1/3$ and the same $\\lambda $. We also explore how the composition of theses universes can be interpreted in terms of known fluids. It is of interest to note that accelerated solutions previously found for the late time evolution also represent regular solutions at early times.

  13. Regularity and Complexity in Dynamical Systems

    CERN Document Server

    Luo, Albert C J

    2012-01-01

    Regularity and Complexity in Dynamical Systems describes periodic and chaotic behaviors in dynamical systems, including continuous, discrete, impulsive,discontinuous, and switching systems. In traditional analysis, the periodic and chaotic behaviors in continuous, nonlinear dynamical systems were extensively discussed even if unsolved. In recent years, there has been an increasing amount of interest in periodic and chaotic behaviors in discontinuous dynamical systems because such dynamical systems are prevalent in engineering. Usually,the smoothening of discontinuous dynamical system is adopted in order to use the theory of continuous dynamical systems. However, such technique cannot provide suitable results in such discontinuous systems. In this book, an alternative way is presented to discuss the periodic and chaotic behaviors in discontinuous dynamical systems. This book also: Illustrates new concepts and methodology in discontinuous dynamical systems Uses different ideas to describe complicated dynamical...

  14. A multiresolution method for solving the Poisson equation using high order regularization

    DEFF Research Database (Denmark)

    Hejlesen, Mads Mølholm; Walther, Jens Honore

    2016-01-01

    We present a novel high order multiresolution Poisson solver based on regularized Green's function solutions to obtain exact free-space boundary conditions while using fast Fourier transforms for computational efficiency. Multiresolution is a achieved through local refinement patches and regulari......We present a novel high order multiresolution Poisson solver based on regularized Green's function solutions to obtain exact free-space boundary conditions while using fast Fourier transforms for computational efficiency. Multiresolution is a achieved through local refinement patches...... and regularized Green's functions corresponding to the difference in the spatial resolution between the patches. The full solution is obtained utilizing the linearity of the Poisson equation enabling super-position of solutions. We show that the multiresolution Poisson solver produces convergence rates...

  15. Image reconstruction for ultrasound computed tomography by use of the regularized dual averaging method

    Science.gov (United States)

    Matthews, Thomas P.; Wang, Kun; Li, Cuiping; Duric, Neb; Anastasio, Mark A.

    2017-03-01

    Waveform inversion methods can produce high-resolution reconstructed sound speed images for ultrasound computed tomography; however, they are very computational expensive. Source encoding methods can reduce this computational cost by formulating the image reconstruction problem as a stochastic optimization problem. Here, we solve this optimization problem by the regularized dual averaging method instead of the more commonly used stochastic gradient descent. This new optimization method allows use of non-smooth regularization functions and treats the stochastic data fidelity term in the objective function separately from the deterministic regularization function. This allows noise to be mitigated more effectively. The method further exhibits lower variance in the estimated sound speed distributions across iterations when line search methods are employed.

  16. Regularization of Instantaneous Frequency Attribute Computations

    Science.gov (United States)

    Yedlin, M. J.; Margrave, G. F.; Van Vorst, D. G.; Ben Horin, Y.

    2014-12-01

    We compare two different methods of computation of a temporally local frequency:1) A stabilized instantaneous frequency using the theory of the analytic signal.2) A temporally variant centroid (or dominant) frequency estimated from a time-frequency decomposition.The first method derives from Taner et al (1979) as modified by Fomel (2007) and utilizes the derivative of the instantaneous phase of the analytic signal. The second method computes the power centroid (Cohen, 1995) of the time-frequency spectrum, obtained using either the Gabor or Stockwell Transform. Common to both methods is the necessity of division by a diagonal matrix, which requires appropriate regularization.We modify Fomel's (2007) method by explicitly penalizing the roughness of the estimate. Following Farquharson and Oldenburg (2004), we employ both the L curve and GCV methods to obtain the smoothest model that fits the data in the L2 norm.Using synthetic data, quarry blast, earthquakes and the DPRK tests, our results suggest that the optimal method depends on the data. One of the main applications for this work is the discrimination between blast events and earthquakesFomel, Sergey. " Local seismic attributes." , Geophysics, 72.3 (2007): A29-A33.Cohen, Leon. " Time frequency analysis theory and applications." USA: Prentice Hall, (1995).Farquharson, Colin G., and Douglas W. Oldenburg. "A comparison of automatic techniques for estimating the regularization parameter in non-linear inverse problems." Geophysical Journal International 156.3 (2004): 411-425.Taner, M. Turhan, Fulton Koehler, and R. E. Sheriff. " Complex seismic trace analysis." Geophysics, 44.6 (1979): 1041-1063.

  17. Statistical regularities in the rank-citation profile of scientists.

    Science.gov (United States)

    Petersen, Alexander M; Stanley, H Eugene; Succi, Sauro

    2011-01-01

    Recent science of science research shows that scientific impact measures for journals and individual articles have quantifiable regularities across both time and discipline. However, little is known about the scientific impact distribution at the scale of an individual scientist. We analyze the aggregate production and impact using the rank-citation profile c(i)(r) of 200 distinguished professors and 100 assistant professors. For the entire range of paper rank r, we fit each c(i)(r) to a common distribution function. Since two scientists with equivalent Hirsch h-index can have significantly different c(i)(r) profiles, our results demonstrate the utility of the β(i) scaling parameter in conjunction with h(i) for quantifying individual publication impact. We show that the total number of citations C(i) tallied from a scientist's N(i) papers scales as [Formula: see text]. Such statistical regularities in the input-output patterns of scientists can be used as benchmarks for theoretical models of career progress.

  18. Relaxation and regularity in the calculus of variations

    Science.gov (United States)

    Ferriero, Alessandro

    In this work we prove that, if L(t,u,ξ) is a continuous function in t and u, Borel measurable in ξ, with bounded non-convex pieces in ξ, then any absolutely continuous solution u¯ to the variational problem min{ ∫abL(t,u(t),u˙(t)) dt:u∈W01,1(a,b)} is quasi-regular in the sense of Tonelli, i.e. u¯ is locally Lipschitz on an open set of full measure of [a,b], under the further assumption that either L is Lipschitz continuous in u, locally uniformly in ξ, but not necessarily in t, or L is invariant under a group of C transformations (as in the Noether's theorem). Without one of those further assumptions the solution could be not regular as shown by a recent example in Gratwick and Preiss (2010) [13]; our result is then optimal in this sense. Moreover, we improve the standard hypothesis used so far in Buttazzo et al. (1998) [1], Clarke and Vinter (1985) [5,6], Csörnyei et al. (2008) [7], Tonelli (1915) [15] which have been the Lipschitz continuity of L in u, locally uniform in ξ and t, and some growth condition in ξ. We also show that the relaxed and the original problem have the same solutions (without assuming any of the two further assumptions above). This extends a result in Mariconda and Treu (2004) [14] to the non-autonomous case.

  19. Systemic adaptation to oxidative challenge induced by regular exercise.

    Science.gov (United States)

    Radak, Zsolt; Chung, Hae Young; Goto, Sataro

    2008-01-15

    Exercise is associated with increased ATP need and an enhanced aerobic and/or anaerobic metabolism, which results in an increased formation of reactive oxygen species (ROS). Regular exercise seems to decrease the incidence of a wide range of ROS-associated diseases, including heart disease, type II diabetes, rheumatic arthritis, Alzheimer and Parkinson diseases, and certain cancers. The preventive effect of regular exercise, at least in part, is due to oxidative stress-induced adaptation. The oxidative challenge-related adaptive process of exercise is probably not just dependent upon the generated level of ROS but primarily on the increase in antioxidant and housekeeping enzyme activities, which involves the oxidative damage repair enzymes. Therefore, the effects of exercise resemble the characteristics of hormesis. In addition, it seems that the oxidative challenge-related effects of exercise are systemic. Skeletal muscle, liver, and brain have very different metabolic rates and functions during exercise, but the adaptive response is very similar: increased antioxidant/damage repair enzyme activity, lower oxidative damage, and increased resistance to oxidative stress, due to the changes in redox homeostasis. Hence, it is highly possible that the well-known beneficial effects of exercise are due to the capability of exercise to produce increased levels of ROS. Or in other words, it seems that the vulnerability of the body to oxidative stress and diseases is significantly enhanced in a sedentary compared to a physically active lifestyle.

  20. Clustering threshold gradient descent regularization: with applications to microarray studies.

    Science.gov (United States)

    Ma, Shuangge; Huang, Jian

    2007-02-15

    An important goal of microarray studies is to discover genes that are associated with clinical outcomes, such as disease status and patient survival. While a typical experiment surveys gene expressions on a global scale, there may be only a small number of genes that have significant influence on a clinical outcome. Moreover, expression data have cluster structures and the genes within a cluster have correlated expressions and coordinated functions, but the effects of individual genes in the same cluster may be different. Accordingly, we seek to build statistical models with the following properties. First, the model is sparse in the sense that only a subset of the parameter vector is non-zero. Second, the cluster structures of gene expressions are properly accounted for. For gene expression data without pathway information, we divide genes into clusters using commonly used methods, such as K-means or hierarchical approaches. The optimal number of clusters is determined using the Gap statistic. We propose a clustering threshold gradient descent regularization (CTGDR) method, for simultaneous cluster selection and within cluster gene selection. We apply this method to binary classification and censored survival analysis. Compared to the standard TGDR and other regularization methods, the CTGDR takes into account the cluster structure and carries out feature selection at both the cluster level and within-cluster gene level. We demonstrate the CTGDR on two studies of cancer classification and two studies correlating survival of lymphoma patients with microarray expressions. R code is available upon request. Supplementary data are available at Bioinformatics online.

  1. Hyperspectral target detection using regularized high-order matched filter

    Science.gov (United States)

    Shi, Zhenwei; Yang, Shuo; Jiang, Zhiguo

    2011-05-01

    Automatic target detection is an important application in the hyperspectral image processing field. Most statistics-based detection algorithms use second-order statistics to construct detectors. However, for target detection in a real hyperspectral image, targets of interest usually occupy a few pixels with small population. In this case, high-order statistics could characterize targets more effectively than second-order statistics. Also, the inherent variation of spectra of targets is an obstacle to successful target detection. In this paper, we propose a regularized high-order matched filter (RHF) which uses high-order statistics to build an objective function and uses a regularized term to make the algorithm robust to target spectral variation. A gradient descent method is used to solve this optimization problem, and we obtain the convergence properties of the RHF. According to the experimental hyperspectral data, the results have shown that the proposed algorithm performed better than those classical second-order statistics-based algorithms and some kernel-based methods.

  2. Spinal Anesthesia in Patients Using Regularly CAT (Catha Edulis Forskal

    Directory of Open Access Journals (Sweden)

    M. Nuzeili

    2009-01-01

    Full Text Available Objective: to study the course of spinal anesthesia in regular users of CAT (Catha edulis Forskal. Subjects and methods. The course of spinal anesthesia was studied in 75 patients in relation to the degree of drug dependence in patients with a national habit to chew systematically CAT, the herbal psychogenic stimulant (pseudoephedrine, amphetamine. According to the dependence and clinical manifestations, all the patients were divided into 3 groups. Results. During spinal anesthesia, arterial hypotension and tachycardia were more common in Group 1 and control patients. Groups 2 and 3 patients with baseline hypertonus of the sympathetic nervous system showed a more significant resistance of indices at this stage and virtually needed no ephedrine administration. The time course of changes in the Cardo autonomic index practically corroborated this regularity. However, in the immediate postoperative period, Group 3 patients’ condition is characterized by the signs of functionally exhausted tone of the sympathetic nervous system, as appear as the signs of discomfort, withdrawal syndrome, respiratory and circulatory disorders, urinary retention, enteroparesis, which require active therapy in an intensive care unit. Thus, Groups 2 and 3 patients have a false temporary intraoperative resistance of hemodynamic parameters and psychoemotional status, which are more dramatically observed in the postoperative period. Key words: spinal analgesia, CAT as a psychogenic stimulant, amphetamine, pseudoephedrine, withdrawal syndrome.

  3. Preparation of Ionic Silsesquioxanes with Regular Structures and Their Hybridization

    Directory of Open Access Journals (Sweden)

    Yoshiro Kaneko

    2012-01-01

    Full Text Available This paper deals with our recent studies on the preparation of ionic silsesquioxanes (SQs with regular structures. Cationic ladder-like polySQs (PSQs with hexagonally stacked structures were successfully prepared by the sol-gel reactions of amino group-containing organotrialkoxysilanes in strong acid aqueous solutions. Self-organization of an ion pair (a salt prepared from the amino group in the organotrialkoxysilane and an acid is the key factor for the formation of such regular structures of the PSQs. It is also reported that the control of the conformational structure of the PSQs was performed by the introduction of the chiral moieties. In addition, we investigated the correlation between the of acid-catalysts and the structures of SQs prepared by the hydrolytic condensation of amino group-containing organotrialkoxysilane, that is, the use of the superacid aqueous solution resulted in the formation of cage-like octaSQ, while the ladder-like PSQs with hexagonally stacked structures were formed from the strong acid aqueous solutions under the same reaction conditions. Furthermore, anion-exchange behaviors of the cationic ladder-like PSQ were investigated with various organic and inorganic compounds, such as anionic surfactants, a polymer, and layered clay minerals, to obtain the functional hybrid materials.

  4. Nonlocal Mumford-Shah regularizers for color image restoration.

    Science.gov (United States)

    Jung, Miyoun; Bresson, Xavier; Chan, Tony F; Vese, Luminita A

    2011-06-01

    We propose here a class of restoration algorithms for color images, based upon the Mumford-Shah (MS) model and nonlocal image information. The Ambrosio-Tortorelli and Shah elliptic approximations are defined to work in a small local neighborhood, which are sufficient to denoise smooth regions with sharp boundaries. However, texture is nonlocal in nature and requires semilocal/non-local information for efficient image denoising and restoration. Inspired from recent works (nonlocal means of Buades, Coll, Morel, and nonlocal total variation of Gilboa, Osher), we extend the local Ambrosio-Tortorelli and Shah approximations to MS functional (MS) to novel nonlocal formulations, for better restoration of fine structures and texture. We present several applications of the proposed nonlocal MS regularizers in image processing such as color image denoising, color image deblurring in the presence of Gaussian or impulse noise, color image inpainting, color image super-resolution, and color filter array demosaicing. In all the applications, the proposed nonlocal regularizers produce superior results over the local ones, especially in image inpainting with large missing regions. We also prove several characterizations of minimizers based upon dual norm formulations.

  5. More academics in regular schools? The effect of regular versus special school placement on academic skills in Dutch primary school students with Down syndrome.

    Science.gov (United States)

    de Graaf, G; van Hove, G; Haveman, M

    2013-01-01

    Studies from the UK have shown that children with Down syndrome acquire more academic skills in regular education. Does this likewise hold true for the Dutch situation, even after the effect of selective placement has been taken into account? In 2006, an extensive questionnaire was sent to 160 parents of (specially and regularly placed) children with Down syndrome (born 1993-2000) in primary education in the Netherlands with a response rate of 76%. Questions were related to the child's school history, academic and non-academic skills, intelligence quotient, parental educational level, the extent to which parents worked on academics with their child at home, and the amount of academic instructional time at school. Academic skills were predicted with the other variables as independents. For the children in regular schools much more time proved to be spent on academics. Academic performance appeared to be predicted reasonably well on the basis of age, non-academic skills, parental educational level and the extent to which parents worked at home on academics. However, more variance could be predicted when the total amount of years that the child spent in regular education was added, especially regarding reading and to a lesser extent regarding writing and math. In addition, we could prove that this finding could not be accounted for by endogenity. Regularly placed children with Down syndrome learn more academics. However, this is not a straight consequence of inclusive placement and age alone, but is also determined by factors such as cognitive functioning, non-academic skills, parental educational level and the extent to which parents worked at home on academics. Nevertheless, it could be proven that the more advanced academic skills of the regularly placed children are not only due to selective placement. The positive effect of regular school on academics appeared to be most pronounced for reading skills. © 2011 The Authors. Journal of Intellectual Disability

  6. Morphisms on infinite alphabets, countable states automata and regular sequences

    Science.gov (United States)

    Zhang, Jie-Meng; Chen, Jin; Guo, Ying-Jun; Wen, Zhi-Xiong

    2017-06-01

    In this paper, we prove that a class of regular sequences can be viewed as projections of fixed points of uniform morphisms on a countable alphabet, and also can be generated by countable states automata. Moreover, we prove that the regularity of some regular sequences is invariant under some codings.

  7. Exclusion of children with intellectual disabilities from regular ...

    African Journals Online (AJOL)

    Study investigated why teachers exclude children with intellectual disability from the regular classrooms in Nigeria. Participants were, 169 regular teachers randomly selected from Oyo and Ogun states. Questionnaire was used to collect data result revealed that 57.4% regular teachers could not cope with children with ID ...

  8. Efeitos dos choques fiscais sobre o mercado de trabalho brasileiro

    Directory of Open Access Journals (Sweden)

    Diogo Baerlocher Carvalho

    2013-06-01

    Full Text Available Esse trabalho tem por objetivo entender quais os efeitos dos choques fiscais sobre o mercado de trabalho brasileiro. Em particular, utiliza se uma abordagem SVAR para avaliar esses efeitos sobre o emprego e o salário real. Os choques fiscais são identificados a partir da imposição de restrições de sinais puras sobre a relação dinâmica entre os gastos do governo, o produto real e a oferta de trabalho. As restrições são obtidas a partir de funções de resposta a impulso Bayesianas derivadas de um modelo DSGE na tradição da Nova Síntese Neoclássica. As funções de resposta a impulso obtidas a partir da abordagem SVAR mostram que choques fiscais aumentam o salário real e o emprego.

  9. Stable sequential Kuhn-Tucker theorem in iterative form or a regularized Uzawa algorithm in a regular nonlinear programming problem

    Science.gov (United States)

    Sumin, M. I.

    2015-06-01

    A parametric nonlinear programming problem in a metric space with an operator equality constraint in a Hilbert space is studied assuming that its lower semicontinuous value function at a chosen individual parameter value has certain subdifferentiability properties in the sense of nonlinear (nonsmooth) analysis. Such subdifferentiability can be understood as the existence of a proximal subgradient or a Fréchet subdifferential. In other words, an individual problem has a corresponding generalized Kuhn-Tucker vector. Under this assumption, a stable sequential Kuhn-Tucker theorem in nondifferential iterative form is proved and discussed in terms of minimizing sequences on the basis of the dual regularization method. This theorem provides necessary and sufficient conditions for the stable construction of a minimizing approximate solution in the sense of Warga in the considered problem, whose initial data can be approximately specified. A substantial difference of the proved theorem from its classical same-named analogue is that the former takes into account the possible instability of the problem in the case of perturbed initial data and, as a consequence, allows for the inherited instability of classical optimality conditions. This theorem can be treated as a regularized generalization of the classical Uzawa algorithm to nonlinear programming problems. Finally, the theorem is applied to the "simplest" nonlinear optimal control problem, namely, to a time-optimal control problem.

  10. Multimaterial topology optimization of contact problems using phase field regularization

    Science.gov (United States)

    Myśliński, Andrzej

    2018-01-01

    The numerical method to solve multimaterial topology optimization problems for elastic bodies in unilateral contact with Tresca friction is developed in the paper. The displacement of the elastic body in contact is governed by elliptic equation with inequality boundary conditions. The body is assumed to consists from more than two distinct isotropic elastic materials. The materials distribution function is chosen as the design variable. Since high contact stress appears during the contact phenomenon the aim of the structural optimization problem is to find such topology of the domain occupied by the body that the normal contact stress along the boundary of the body is minimized. The original cost functional is regularized using the multiphase volume constrained Ginzburg-Landau energy functional rather than the perimeter functional. The first order necessary optimality condition is recalled and used to formulate the generalized gradient flow equations of Allen-Cahn type. The optimal topology is obtained as the steady state of the phase transition governed by the generalized Allen-Cahn equation. As the interface width parameter tends to zero the transition of the phase field model to the level set model is studied. The optimization problem is solved numerically using the operator splitting approach combined with the projection gradient method. Numerical examples confirming the applicability of the proposed method are provided and discussed.

  11. Efeitos ecotoxicológicos das saxitoxinas em Hoplias malabaricus

    OpenAIRE

    Silva, Cesar Aparecido da

    2012-01-01

    Resumo: Floracoes de cianobacterias podutoras de saxitoxinas (STXs), como a Cylindrospermopsis raciborskii, tem se tornado um grave problema ambiental, especialmente no sul do Brasil, onde a especie ja e dominante em reservatorio de abastecimento publico. As STXs sao neurotoxinas que atuam bloquendo os canais de sodio (Na+) dos neuronios, o que pode levar a morte por parada respiratoria. Entretanto, a bioacumulacao deste tipo de substancia na cadeia trofica e seus efeitos ecotoxicologicos, pr...

  12. O efeito trabalhador adicional para filhos no Brasil

    Directory of Open Access Journals (Sweden)

    Elzira Lúcia de Oliveira

    2014-06-01

    Full Text Available O objetivo deste trabalho é testar a hipótese da existência do efeito trabalhador adicional para filhos no Brasil, procurando identificar se a situação de desemprego do chefe de família fará com que algum membro da família, cuja condição seja filho, transite para a População Economicamente Ativa - PEA. A base de dados utilizada foi a Pesquisa Mensal de Emprego - PME realizada pelo IBGE, que permite a construção de painéis para análise longitudinal de dados. A hipótese foi testada para pelo menos um filho com idade de 10 a 18 anos, entre 2002 e 2013, para as regiões metropolitanas de Belo Horizonte, Salvador, Porto Alegre, São Paulo, Rio de Janeiro e Recife, que compõem a área de abrangência da PME. Este trabalho admite a existência de diferencial por sexo do chefe para o efeito trabalhador adicional de filhos de 10 a 18 anos. Os resultados mostraram haver um efeito positivo maior para chefes homens do que para chefes mulheres, sendo que a variável de transição do filho para a atividade não apresentou significância estatística que permitisse assumir a existência do efeito. Corroborou-se a hipótese da existência de diferencial por sexo, contudo no sentido oposto ao da hipótese assumida.

  13. Efficient regularization with wavelet sparsity constraints in photoacoustic tomography

    Science.gov (United States)

    Frikel, Jürgen; Haltmeier, Markus

    2018-02-01

    In this paper, we consider the reconstruction problem of photoacoustic tomography (PAT) with a flat observation surface. We develop a direct reconstruction method that employs regularization with wavelet sparsity constraints. To that end, we derive a wavelet-vaguelette decomposition (WVD) for the PAT forward operator and a corresponding explicit reconstruction formula in the case of exact data. In the case of noisy data, we combine the WVD reconstruction formula with soft-thresholding, which yields a spatially adaptive estimation method. We demonstrate that our method is statistically optimal for white random noise if the unknown function is assumed to lie in any Besov-ball. We present generalizations of this approach and, in particular, we discuss the combination of PAT-vaguelette soft-thresholding with a total variation (TV) prior. We also provide an efficient implementation of the PAT-vaguelette transform that leads to fast image reconstruction algorithms supported by numerical results.

  14. Regular Black Hole Metric with Three Constants of Motion

    CERN Document Server

    Johannsen, Tim

    2015-01-01

    According to the no-hair theorem, astrophysical black holes are uniquely characterized by their masses and spins and are described by the Kerr metric. Several parametric spacetimes which deviate from the Kerr metric have been proposed in order to test this theorem with observations of black holes in both the electromagnetic and gravitational-wave spectra. Such metrics often contain naked singularities or closed timelike curves in the vicinity of the compact objects that can limit the applicability of the metrics to compact objects that do not spin rapidly, and generally admit only two constants of motion. The existence of a third constant, however, can facilitate the calculation of observables, because the equations of motion can be written in first-order form. In this paper, I design a Kerr-like black hole metric which is regular everywhere outside of the event horizon, possesses three independent constants of motion, and depends nonlinearly on four free functions that parameterize potential deviations from ...

  15. Regularizing Inverse Preconditioners for Symmetric Band Toeplitz Matrices

    Directory of Open Access Journals (Sweden)

    Lotti G

    2007-01-01

    Full Text Available Image restoration is a widely studied discrete ill-posed problem. Among the many regularization methods used for treating the problem, iterative methods have been shown to be effective. In this paper, we consider the case of a blurring function defined by space invariant and band-limited PSF, modeled by a linear system that has a band block Toeplitz structure with band Toeplitz blocks. In order to reduce the number of iterations required to obtain acceptable reconstructions, in 13 an inverse Toeplitz preconditioner for problems with a Toeplitz structure was proposed. The cost per iteration is of operations, where is the pixel number of the 2D image. In this paper, we propose inverse preconditioners with a band Toeplitz structure, which lower the cost to and in experiments showed the same speed of convergence and reconstruction efficiency as the inverse Toeplitz preconditioner.

  16. Regularized multivariate regression models with skew-t error distributions

    KAUST Repository

    Chen, Lianfu

    2014-06-01

    We consider regularization of the parameters in multivariate linear regression models with the errors having a multivariate skew-t distribution. An iterative penalized likelihood procedure is proposed for constructing sparse estimators of both the regression coefficient and inverse scale matrices simultaneously. The sparsity is introduced through penalizing the negative log-likelihood by adding L1-penalties on the entries of the two matrices. Taking advantage of the hierarchical representation of skew-t distributions, and using the expectation conditional maximization (ECM) algorithm, we reduce the problem to penalized normal likelihood and develop a procedure to minimize the ensuing objective function. Using a simulation study the performance of the method is assessed, and the methodology is illustrated using a real data set with a 24-dimensional response vector. © 2014 Elsevier B.V.

  17. Shearlet-Wavelet Regularized Semismooth Newton Iteration for Image Restoration

    Directory of Open Access Journals (Sweden)

    Liang Ding

    2015-01-01

    Full Text Available Image normally has both dots-like and curve structures. But the traditional wavelet or multidirectional wave (ridgelet, contourlet, curvelet, etc. could only restore one of these structures efficiently so that the restoration results for complex images are unsatisfactory. For the image restoration, this paper adopted a strategy of combined shearlet and wavelet frame and proposed a new restoration method. Theoretically, image sparse representation of dots-like and curve structures could be achieved by shearlet and wavelet, respectively. Under the L1 regularization, the two frame-sparse structures could show their respective advantages and efficiently restore the two structures. In order to achieve superlinear convergence, this paper applied semismooth Newton method based on subgradient to solve objective functional without differentiability. Finally, through numerical results, the effectiveness of this strategy was validated, which presented outstanding advantages for any individual frame alone. Some detailed information that could not be restored in individual frame could be clearly demonstrated with this strategy.

  18. Iron status of regular voluntary blood donors

    Directory of Open Access Journals (Sweden)

    Mahida Vilsu

    2008-01-01

    Full Text Available Background: Our blood bank is a regional blood transfusion centre, which accepts blood only from voluntary donors. Aim: The aim is to study iron status of regular voluntary donors who donated their blood at least twice in a year. Materials and Methods: Prior to blood donation, blood samples of 220 male and 30 female voluntary donors were collected. Control included 100 each male and female healthy individuals in the 18- to 60-year age group, who never donated blood and did not have any chronic infection. In the study and control groups, about 10% subjects consumed non-vegetarian diet. After investigation, 85 males and 56 females having haemoglobin (Hb levels above 12.5 g/dl were selected as controls. Donors were divided into ≤10, 11-20, 21-50 and> 50 blood donation categories. Majority of the donors in> 50 donation category donated blood four times in a year, whereas the remaining donors donated two to three times per year. Haematological parameters were measured on fully automatic haematology analyzer, serum iron and total iron-binding capacity (TIBC by biochemical methods, ferritin using ELISA kits and transferrin using immunoturbidometry kits. Iron/TIBC ratio x 100 gave percentage of transferrin saturation value. Statistical Analysis: Statistical evaluation was done by mean, standard deviation, pair t -test, χ2 and anova ( F -test. Results: Preliminary analysis revealed that there was no significant difference in the iron profile of vegetarian and non-vegetarian subjects or controls and the donors donating < 20 times. Significant increase or decrease was observed in mean values of various haematological and iron parameters in donors who donated blood for> 20 times ( P < 0.001, compared to controls. Anaemia, iron deficiency and depletion of iron stores were more prevalent in female donors ( P < 0.05 compared to males and especially in those male donors who donated their blood for more than 20 times. Conclusion: Regular voluntary blood

  19. Efeitos de diversos fatores sobre o comportamento alimentar de adolescentes

    Directory of Open Access Journals (Sweden)

    Leonardo de Sousa Fortes

    2013-11-01

    Full Text Available Pesquisadores sugerem que o comportamento alimentar inadequado (CAI em jovens pode sofrer influências de diversos fatores. No entanto, os resultados têm sido controversos. Deste modo, o objetivo do presente estudo foi averiguar os efeitos de insatisfação corporal (IC, grau de comprometimento psicológico ao exercício (GCPE, nível habitual de atividade física (NAF, índice de massa corporal (IMC, percentual de gordura e etnia sobre o CAI de adolescentes. Participaram 362 jovens de ambos os sexos com idades entre 10 e 19 anos. O Eating attitudes test (EAT-26 foi utilizado para avaliar o CAI. Ademais, utilizou-se o Body shape questionnaire, a commitment exercise scale e o International physical activity questionnaire para avaliar IC, GCPE e NAF, respectivamente. Conduziu-se análise multivariada e regressão múltipla para analisar os dados. Os resultados evidenciaram que a IC, o GCPE, IMC e percentual de gordura influenciaram significativamente (p < 0,05 os escores das subescalas do EAT-26, tanto no sexo feminino, quanto no masculino. No entanto, os efeitos das variâncias foram diferentes entre os sexos. Concluiu-se que IC e o IMC foram os principais fatores que promoveram efeitos significativos nos distintos construtos do comportamento alimentar avaliados pelo EAT-26 em ambos os sexos.

  20. A regularity-based modeling of oil borehole logs

    Science.gov (United States)

    Gaci, Said; Zaourar, Naima

    2013-04-01

    Multifractional Brownian motions (mBms) are successfully used to describe borehole logs behavior. These local fractal models allow to investigate the depth-evolution of regularity of the logs, quantified by the Hölder exponent (H). In this study, a regularity analysis is carried out on datasets recorded in Algerian oil boreholes located in different geological settings. The obtained regularity profiles show a clear correlation with lithology. Each lithological discontinuity corresponds to a jump in H value. Moreover, for a given borehole, all the regularity logs are significantly correlated and lead to similar lithological segmentations. Therefore, the Hölderian regularity is a robust property which can be used to characterize lithological heterogeneities. However, this study does not draw any relation between the recorded physical property and its estimated regularity degree for all the analyzed logs. Keywords: well logs, regularity, Hölder exponent, multifractional Brownian motion

  1. Regularities and irregularities in order flow data

    Science.gov (United States)

    Theissen, Martin; Krause, Sebastian M.; Guhr, Thomas

    2017-11-01

    We identify and analyze statistical regularities and irregularities in the recent order flow of different NASDAQ stocks, focusing on the positions where orders are placed in the order book. This includes limit orders being placed outside of the spread, inside the spread and (effective) market orders. Based on the pairwise comparison of the order flow of different stocks, we perform a clustering of stocks into groups with similar behavior. This is useful to assess systemic aspects of stock price dynamics. We find that limit order placement inside the spread is strongly determined by the dynamics of the spread size. Most orders, however, arrive outside of the spread. While for some stocks order placement on or next to the quotes is dominating, deeper price levels are more important for other stocks. As market orders are usually adjusted to the quote volume, the impact of market orders depends on the order book structure, which we find to be quite diverse among the analyzed stocks as a result of the way limit order placement takes place.

  2. Flip to Regular Triangulation and Convex Hull.

    Science.gov (United States)

    Gao, Mingcen; Cao, Thanh-Tung; Tan, Tiow-Seng

    2017-02-01

    Flip is a simple and local operation to transform one triangulation to another. It makes changes only to some neighboring simplices, without considering any attribute or configuration global in nature to the triangulation. Thanks to this characteristic, several flips can be independently applied to different small, non-overlapping regions of one triangulation. Such operation is favored when designing algorithms for data-parallel, massively multithreaded hardware, such as the GPU. However, most existing flip algorithms are designed to be executed sequentially, and usually need some restrictions on the execution order of flips, making them hard to be adapted to parallel computation. In this paper, we present an in depth study of flip algorithms in low dimensions, with the emphasis on the flexibility of their execution order. In particular, we propose a series of provably correct flip algorithms for regular triangulation and convex hull in 2D and 3D, with implementations for both CPUs and GPUs. Our experiment shows that our GPU implementation for constructing these structures from a given point set achieves up to two orders of magnitude of speedup over other popular single-threaded CPU implementation of existing algorithms.

  3. Toroidal regularization of the guiding center Lagrangian

    Science.gov (United States)

    Burby, J. W.; Ellison, C. L.

    2017-11-01

    In the Lagrangian theory of guiding center motion, an effective magnetic field B*=B +(m /e )v∥∇× b appears prominently in the equations of motion. Because the parallel component of this field can vanish, there is a range of parallel velocities where the Lagrangian guiding center equations of motion are either ill-defined or very badly behaved. Moreover, the velocity dependence of B* greatly complicates the identification of canonical variables and therefore the formulation of symplectic integrators for guiding center dynamics. This letter introduces a simple coordinate transformation that alleviates both these problems simultaneously. In the new coordinates, the Liouville volume element is equal to the toroidal contravariant component of the magnetic field. Consequently, the large-velocity singularity is completely eliminated. Moreover, passing from the new coordinate system to canonical coordinates is extremely simple, even if the magnetic field is devoid of flux surfaces. We demonstrate the utility of this approach in regularizing the guiding center Lagrangian by presenting a new and stable one-step variational integrator for guiding centers moving in arbitrary time-dependent electromagnetic fields.

  4. Multiparametric tissue abnormality characterization using manifold regularization

    Science.gov (United States)

    Batmanghelich, Kayhan; Wu, Xiaoying; Zacharaki, Evangelia; Markowitz, Clyde E.; Davatzikos, Christos; Verma, Ragini

    2008-03-01

    Tissue abnormality characterization is a generalized segmentation problem which aims at determining a continuous score that can be assigned to the tissue which characterizes the extent of tissue deterioration, with completely healthy tissue being one end of the spectrum and fully abnormal tissue such as lesions, being on the other end. Our method is based on the assumptions that there is some tissue that is neither fully healthy or nor completely abnormal but lies in between the two in terms of abnormality; and that the voxel-wise score of tissue abnormality lies on a spatially and temporally smooth manifold of abnormality. Unlike in a pure classification problem which associates an independent label with each voxel without considering correlation with neighbors, or an absolute clustering problem which does not consider a priori knowledge of tissue type, we assume that diseased and healthy tissue lie on a manifold that encompasses the healthy tissue and diseased tissue, stretching from one to the other. We propose a semi-supervised method for determining such as abnormality manifold, using multi-parametric features incorporated into a support vector machine framework in combination with manifold regularization. We apply the framework towards the characterization of tissue abnormality to brains of multiple sclerosis patients.

  5. One-dimensional QCD in thimble regularization

    Science.gov (United States)

    Di Renzo, F.; Eruzzi, G.

    2018-01-01

    QCD in 0 +1 dimensions is numerically solved via thimble regularization. In the context of this toy model, a general formalism is presented for S U (N ) theories. The sign problem that the theory displays is a genuine one, stemming from a (quark) chemical potential. Three stationary points are present in the original (real) domain of integration, so that contributions from all the thimbles associated to them are to be taken into account: we show how semiclassical computations can provide hints on the regions of parameter space where this is absolutely crucial. Known analytical results for the chiral condensate and the Polyakov loop are correctly reproduced: this is in particular trivial at high values of the number of flavors Nf. In this regime we notice that the single thimble dominance scenario takes place (the dominant thimble is the one associated to the identity). At low values of Nf computations can be more difficult. It is important to stress that this is not at all a consequence of the original sign problem (not even via the residual phase). The latter is always under control, while accidental, delicate cancelations of contributions coming from different thimbles can be in place in (restricted) regions of the parameter space.

  6. Conditions on optimal support recovery in unmixing problems by means of multi-penalty regularization

    Science.gov (United States)

    Grasmair, Markus; Naumova, Valeriya

    2016-10-01

    Inspired by several real-life applications in audio processing and medical image analysis, where the quantity of interest is generated by several sources to be accurately modeled and separated, as well as by recent advances in regularization theory and optimization, we study the conditions on optimal support recovery in inverse problems of unmixing type by means of multi-penalty regularization. We consider and analyze a regularization functional composed of a data-fidelity term, where signal and noise are additively mixed, a non-smooth, convex, sparsity promoting term, and a quadratic penalty term to model the noise. We prove not only that the well-established theory for sparse recovery in the single parameter case can be translated to the multi-penalty settings, but we also demonstrate the enhanced properties of multi-penalty regularization in terms of support identification compared to sole {{\\ell }}1-minimization. We additionally confirm and support the theoretical results by extensive numerical simulations, which give a statistics of robustness of the multi-penalty regularization scheme with respect to the single-parameter counterpart. Eventually, we confirm a significant improvement in performance compared to standard {{\\ell }}1-regularization for compressive sensing problems considered in our experiments.

  7. The mathematical law of evolutionary information dynamics and an observer's evolution regularities

    CERN Document Server

    Lerner, Vladimir S

    2011-01-01

    An interactive stochastics, evaluated by an entropy functional (EF) of a random field and informational process' path functional (IPF), allows us modeling the evolutionary information processes and revealing regularities of evolution dynamics. Conventional Shannon's information measure evaluates a sequence of the process' static events for each information state and do not reveal hidden dynamic connections between these events. The paper formulates the mathematical forms of the information regularities, based on a minimax variation principle (VP) for IPF, applied to the evolution's both random microprocesses and dynamic macroprocesses. The paper shows that the VP single form of the mathematical law leads to the following evolutionary regularities: -creation of the order from stochastics through the evolutionary macrodynamics, described by a gradient of dynamic potential, evolutionary speed and the evolutionary conditions of a fitness and diversity; -the evolutionary hierarchy with growing information values a...

  8. Accurate mask-based spatially regularized correlation filter for visual tracking

    Science.gov (United States)

    Gu, Xiaodong; Xu, Xinping

    2017-01-01

    Recently, discriminative correlation filter (DCF)-based trackers have achieved extremely successful results in many competitions and benchmarks. These methods utilize a periodic assumption of the training samples to efficiently learn a classifier. However, this assumption will produce unwanted boundary effects, which severely degrade the tracking performance. Correlation filters with limited boundaries and spatially regularized DCFs were proposed to reduce boundary effects. However, their methods used the fixed mask or predesigned weights function, respectively, which was unsuitable for large appearance variation. We propose an accurate mask-based spatially regularized correlation filter for visual tracking. Our augmented objective can reduce the boundary effect even in large appearance variation. In our algorithm, the masking matrix is converted into the regularized function that acts on the correlation filter in frequency domain, which makes the algorithm fast convergence. Our online tracking algorithm performs favorably against state-of-the-art trackers on OTB-2015 Benchmark in terms of efficiency, accuracy, and robustness.

  9. Construction of normal-regular decisions of Bessel typed special system

    Science.gov (United States)

    Tasmambetov, Zhaksylyk N.; Talipova, Meiramgul Zh.

    2017-09-01

    Studying a special system of differential equations in the separate production of the second order is solved by the degenerate hypergeometric function reducing to the Bessel functions of two variables. To construct a solution of this system near regular and irregular singularities, we use the method of Frobenius-Latysheva applying the concepts of rank and antirank. There is proved the basic theorem that establishes the existence of four linearly independent solutions of studying system type of Bessel. To prove the existence of normal-regular solutions we establish necessary conditions for the existence of such solutions. The existence and convergence of a normally regular solution are shown using the notion of rank and antirank.

  10. Efeitos do hipotireoidismo no sistema reprodutor masculino

    OpenAIRE

    Rocha, Aline Silva [UNESP; Papa, Frederico Ozanam [UNESP

    2012-01-01

    Thyroid hormones are essential for growth, development and metabolism in many tissues and organs. Currently, it is known that these hormones play an important activity in testicular function in several species through specific receptors located, mainly, in Sertoli cells. The thyroid dysfunction, particularly hypothyroidism, affects testicular steroidogenesis and spermatogenesis and may lead to infertility. Although several reproductive changes have been related in animals with hypothyroidism,...

  11. Elementary Particle Spectroscopy in Regular Solid Rewrite

    Science.gov (United States)

    Trell, Erik

    2008-10-01

    The Nilpotent Universal Computer Rewrite System (NUCRS) has operationalized the radical ontological dilemma of Nothing at All versus Anything at All down to the ground recursive syntax and principal mathematical realisation of this categorical dichotomy as such and so governing all its sui generis modalities, leading to fulfilment of their individual terms and compass when the respective choice sequence operations are brought to closure. Focussing on the general grammar, NUCRS by pure logic and its algebraic notations hence bootstraps Quantum Mechanics, aware that it "is the likely keystone of a fundamental computational foundation" also for e.g. physics, molecular biology and neuroscience. The present work deals with classical geometry where morphology is the modality, and ventures that the ancient regular solids are its specific rewrite system, in effect extensively anticipating the detailed elementary particle spectroscopy, and further on to essential structures at large both over the inorganic and organic realms. The geodetic antipode to Nothing is extension, with natural eigenvector the endless straight line which when deployed according to the NUCRS as well as Plotelemeian topographic prescriptions forms a real three-dimensional eigenspace with cubical eigenelements where observed quark-skewed quantum-chromodynamical particle events self-generate as an Aristotelean phase transition between the straight and round extremes of absolute endlessness under the symmetry- and gauge-preserving, canonical coset decomposition SO(3)×O(5) of Lie algebra SU(3). The cubical eigen-space and eigen-elements are the parental state and frame, and the other solids are a range of transition matrix elements and portions adapting to the spherical root vector symmetries and so reproducibly reproducing the elementary particle spectroscopy, including a modular, truncated octahedron nano-composition of the Electron which piecemeal enter into molecular structures or compressed to each

  12. Secant method with regularly continuous divided differences

    National Research Council Canada - National Science Library

    Galperin, A

    2006-01-01

    .... As we show, it allows to obtain broader convergence domains and tighter error bounds. Another distinctive feature of our analysis is the use of a functional equation for precise description of convergence domain of the majorant generator...

  13. Analysis of bubble plume spacing produced by regular breaking waves

    Science.gov (United States)

    Phaksopa, J.; Haller, M. C.

    2012-12-01

    The breaking wave process in the ocean is a significant mechanism for energy dissipation, splash, and entrainment of air. The relationship between breaking waves and bubble plume characteristics is still a mystery because of the complexity of the breaking wave mechanism. This study takes a unique approach to quantitatively analyze bubble plumes produced by regular breaking waves. Various previous studies have investigated the formation and the characteristics of bubble plumes using either field observations, laboratory experiments, or numerical modeling However, in most observational work the plume characteristics have been studied from the underneath the water surface. In addition, though numerical simulations are able to include much of the important physics, the computational costs are high and bubble plume events are only simulated for short times. Hence, bubble plume evolution and generation throughout the surf zone is not yet computationally feasible. In the present work we take a unique approach to analyzing bubble plumes. These data may be of use for model/data comparisons as numerical simulations become more tractable. The remotely sensed video data from freshwater breaking waves in the OSU Large Wave Flume (Catalan and Haller, 2008) are analyzed. The data set contains six different regular wave conditions and the video intensity data are used to estimate the spacing of plume events (wavenumber spectrum), to calculate the spectral width (i.e. the range of plume spacing), and to relate these with the wave conditions. The video intensity data capture the evolution of the wave passage over a fixed bed arranged in a bar-trough morphology. Bright regions represent the moving path or trajectory coincident with bubble plume of each wave. It also shows the bubble foam were generated and released from wave crest shown in the form of bubble tails with almost regular spacing for each wave. The bubble tails show that most bubbles did not move along with wave. For the

  14. Study of limit cycles in piecewise smooth perturbations of Hamiltonian centers via regularization method

    Directory of Open Access Journals (Sweden)

    Luis Mello

    2017-11-01

    Full Text Available In this article we study the existence and positions of limit cycles in piecewise smooth perturbations of planar Hamiltonian centers. By using the regularization method we provide an analytical expression for the first order Melnikov function frequently used in the literature directly from the original non-smooth problem.

  15. Semiclassical Weyl Formula for a Class of Weakly Regular Elliptic Operators

    Energy Technology Data Exchange (ETDEWEB)

    Zielinski, Lech [Universite du Littoral, LMPA, Centre Mi-Voix (France)], E-mail: Lech.Zielinski@lmpa.univ-littoral.fr

    2006-02-15

    We investigate the semiclassical Weyl formula describing the asymptotic behaviour of the counting function for the number of eigenvalues in the case of self-adjoint elliptic differential operators satisfying weak regularity hypotheses. We consider symbols with possible critical points and with coefficients which have Hoelder continuous derivatives of first order.

  16. Regular exercise, anxiety, depression and personality: A population-based study

    NARCIS (Netherlands)

    de Moor, M.H.M.; Beem, A.L.; Stubbe, J.H.; Boomsma, D.I.; de Geus, E.J.C.

    2006-01-01

    Objectives: To examine whether regular exercise is associated with anxiety, depression and personality in a large population-based sample as a function of gender and age. Methods: The sample consisted of adolescent and adult twins and their families (N = 19,288) who participated in the study on

  17. Regular exercise, anxiety, depression and personality: a population-based study

    NARCIS (Netherlands)

    de Moor, M. H. M.; Beem, A. L.; Stubbe, J. H.; Boomsma, D. I.; de Geus, E. J. C.

    2006-01-01

    To examine whether regular exercise is associated with anxiety, depression and personality in a large population-based sample as a function of gender and age. The sample consisted of adolescent and adult twins and their families (N=19,288) who participated in the study on lifestyle and health from

  18. ProRegIn: A regularity index for the selection of native-like tertiary ...

    Indian Academy of Sciences (India)

    2006-12-18

    Dec 18, 2006 ... Keywords. Dihedral angles of loops; protein data bank; protein tertiary structure selection; regularity index; scoring function ... Department of Chemistry and Supercomputing Facility for Bioinformatics and Computational Biology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110 016, India ...

  19. A Durbin-Levinson Regularized Estimator of High Dimensional Autocovariance Matrices

    DEFF Research Database (Denmark)

    Proietti, Tommaso; Giovannelli, Alessandro

    on banding and tapering the sample autocovariance matrix. This paper proposes and evaluates an alternative approach, based on regularizing the sample partial autocorrelation function, via a modified Durbin-Levinson algorithm that receives as input the banded and tapered partial autocorrelations and returns...

  20. Regularized binormal ROC method in disease classification using microarray data

    Directory of Open Access Journals (Sweden)

    Huang Jian

    2006-05-01

    Full Text Available Abstract Background An important application of microarrays is to discover genomic biomarkers, among tens of thousands of genes assayed, for disease diagnosis and prognosis. Thus it is of interest to develop efficient statistical methods that can simultaneously identify important biomarkers from such high-throughput genomic data and construct appropriate classification rules. It is also of interest to develop methods for evaluation of classification performance and ranking of identified biomarkers. Results The ROC (receiver operating characteristic technique has been widely used in disease classification with low dimensional biomarkers. Compared with the empirical ROC approach, the binormal ROC is computationally more affordable and robust in small sample size cases. We propose using the binormal AUC (area under the ROC curve as the objective function for two-sample classification, and the scaled threshold gradient directed regularization method for regularized estimation and biomarker selection. Tuning parameter selection is based on V-fold cross validation. We develop Monte Carlo based methods for evaluating the stability of individual biomarkers and overall prediction performance. Extensive simulation studies show that the proposed approach can generate parsimonious models with excellent classification and prediction performance, under most simulated scenarios including model mis-specification. Application of the method to two cancer studies shows that the identified genes are reasonably stable with satisfactory prediction performance and biologically sound implications. The overall classification performance is satisfactory, with small classification errors and large AUCs. Conclusion In comparison to existing methods, the proposed approach is computationally more affordable without losing the optimality possessed by the standard ROC method.

  1. Tanning beauty ideals among Swedish adults who exercise regularly

    OpenAIRE

    Cedercreutz, Isabella

    2016-01-01

    Tanning beauty ideals among Swedish adults who exercise regularly Introduction: The majority of the Swedish population exercise regularly, and it has been reported that they believe having an attractive body is important. While research has shown that Swedes wish to be tanned, it is unknown whether there are any correlations to their exercise habits. Aims: The primary aim was to determine tanned skin tone ideals and tanning beauty ideals among regularly exercising Swedish adults. Associati...

  2. Existence domains for invariant reactions in binary regular solution ...

    Indian Academy of Sciences (India)

    Unknown

    two phases (e.g. a liquid and a solid phase) has been examined using the regular solution model. The necessary conditions for the ... Binary phase diagrams; invariant reactions; regular solution model. 1. Introduction. Using the regular ...... Nb–Ta, Nb–W, Os–Re, Os–Ru, Pd–Pt, Pt–Rh,. Re–Ru, Ta–W, V–W]. R + T MN [Cr–V, ...

  3. Phase-regularized polygon computer-generated holograms.

    Science.gov (United States)

    Im, Dajeong; Moon, Eunkyoung; Park, Yohan; Lee, Deokhwan; Hahn, Joonku; Kim, Hwi

    2014-06-15

    The dark-line defect problem in the conventional polygon computer-generated hologram (CGH) is addressed. To resolve this problem, we clarify the physical origin of the defect and address the concept of phase-regularization. A novel synthesis algorithm for a phase-regularized polygon CGH for generating photorealistic defect-free holographic images is proposed. The optical reconstruction results of the phase-regularized polygon CGHs without the dark-line defects are presented.

  4. Dimensional regularization in position space and a forest formula for regularized Epstein-Glaser renormalization

    Energy Technology Data Exchange (ETDEWEB)

    Keller, Kai Johannes

    2010-04-15

    The present work contains a consistent formulation of the methods of dimensional regularization (DimReg) and minimal subtraction (MS) in Minkowski position space. The methods are implemented into the framework of perturbative Algebraic Quantum Field Theory (pAQFT). The developed methods are used to solve the Epstein-Glaser recursion for the construction of time-ordered products in all orders of causal perturbation theory. A solution is given in terms of a forest formula in the sense of Zimmermann. A relation to the alternative approach to renormalization theory using Hopf algebras is established. (orig.)

  5. The entire regularization path for the support vector domain description

    DEFF Research Database (Denmark)

    Sjöstrand, Karl; Larsen, Rasmus

    2006-01-01

    -class support vector machine classifier. Recently, it was shown that the regularization path of the support vector machine is piecewise linear, and that the entire path can be computed efficiently. This pa- per shows that this property carries over to the support vector domain description. Using our results...... the solution to the one-class classification can be solved for any amount of regularization with roughly the same computational complexity required to solve for a particularly value of the regularization parameter. The possibility of evaluating the results for any amount of regularization not only offers more...

  6. The analyzation of 2D complicated regular polygon photonic lattice

    Science.gov (United States)

    Lv, Jing; Gao, Yuanmei

    2017-06-01

    We have numerically simulated the light intensity distribution, phase distribution, far-field diffraction of the two dimensional (2D) regular octagon and regular dodecagon lattices in detail. In addition, using the plane wave expansion (PWE) method, we numerically calculate the energy band of the two lattices. Both of the photonic lattices have the band gap. And the regular octagon lattice possesses the wide complete band gap while the regular dodecagon lattice has the incomplete gap. Moreover, we simulated the preliminary transmission image of photonic lattices. It may inspire the academic research both in light control and soliton.

  7. Adaptive Regularization of Neural Networks Using Conjugate Gradient

    DEFF Research Database (Denmark)

    Goutte, Cyril; Larsen, Jan

    1998-01-01

    Andersen et al. (1997) and Larsen et al. (1996, 1997) suggested a regularization scheme which iteratively adapts regularization parameters by minimizing validation error using simple gradient descent. In this contribution we present an improved algorithm based on the conjugate gradient technique........ Numerical experiments with feedforward neural networks successfully demonstrate improved generalization ability and lower computational cost......Andersen et al. (1997) and Larsen et al. (1996, 1997) suggested a regularization scheme which iteratively adapts regularization parameters by minimizing validation error using simple gradient descent. In this contribution we present an improved algorithm based on the conjugate gradient technique...

  8. Learning Convex Regularizers for Optimal Bayesian Denoising

    Science.gov (United States)

    Nguyen, Ha Q.; Bostan, Emrah; Unser, Michael

    2018-02-01

    We propose a data-driven algorithm for the maximum a posteriori (MAP) estimation of stochastic processes from noisy observations. The primary statistical properties of the sought signal is specified by the penalty function (i.e., negative logarithm of the prior probability density function). Our alternating direction method of multipliers (ADMM)-based approach translates the estimation task into successive applications of the proximal mapping of the penalty function. Capitalizing on this direct link, we define the proximal operator as a parametric spline curve and optimize the spline coefficients by minimizing the average reconstruction error for a given training set. The key aspects of our learning method are that the associated penalty function is constrained to be convex and the convergence of the ADMM iterations is proven. As a result of these theoretical guarantees, adaptation of the proposed framework to different levels of measurement noise is extremely simple and does not require any retraining. We apply our method to estimation of both sparse and non-sparse models of L\\'{e}vy processes for which the minimum mean square error (MMSE) estimators are available. We carry out a single training session and perform comparisons at various signal-to-noise ratio (SNR) values. Simulations illustrate that the performance of our algorithm is practically identical to the one of the MMSE estimator irrespective of the noise power.

  9. Regularity-Preserving but not Reflecting Encodings

    NARCIS (Netherlands)

    Endrullis, J.; Grabmayer, C.A.; Hendriks, R.D.A.; Palamidessi, C.

    2015-01-01

    Encodings, that is, injective functions from words to words, have been studied extensively in several settings. In computability theory the notion of encoding is crucial for defining computability on arbitrary domains, as well as for comparing the power of models of computation. In language theory

  10. Abel transforms with low regularity with applications to x-ray tomography on spherically symmetric manifolds

    Science.gov (United States)

    de Hoop, Maarten V.; Ilmavirta, Joonas

    2017-12-01

    We study ray transforms on spherically symmetric manifolds with a piecewise C1, 1 metric. Assuming the Herglotz condition, the x-ray transform is injective on the space of L 2 functions on such manifolds. We also prove injectivity results for broken ray transforms (with and without periodicity) on such manifolds with a C1, 1 metric. To make these problems tractable in low regularity, we introduce and study a class of generalized Abel transforms and study their properties. This low regularity setting is relevant for geophysical applications.

  11. Electrostatic self-force in the field of an (n + 1)-dimensional black hole: Dimensional regularization

    Energy Technology Data Exchange (ETDEWEB)

    Grats, Yu. V., E-mail: grats@phys.msu.ru; Spirin, P. A. [Moscow State University (Russian Federation)

    2016-01-15

    The self-energy of a classical charged particle localized at a relatively large distance outside the event horizon of an (n + 1)-dimensional Schwarzschild–Tangherlini black hole for an arbitrary n ≥ 3 is calculated. An expression for the electrostatic Green function is derived in the first two orders of the perturbation theory. Dimensional regularization is proposed to be used to regularize the corresponding formally divergent expression for the self-energy. The derived expression for the renormalized self-energy is compared with the results of other authors.

  12. Graph Regularized Nonnegative Matrix Factorization with Sparse Coding

    Directory of Open Access Journals (Sweden)

    Chuang Lin

    2015-01-01

    Full Text Available In this paper, we propose a sparseness constraint NMF method, named graph regularized matrix factorization with sparse coding (GRNMF_SC. By combining manifold learning and sparse coding techniques together, GRNMF_SC can efficiently extract the basic vectors from the data space, which preserves the intrinsic manifold structure and also the local features of original data. The target function of our method is easy to propose, while the solving procedures are really nontrivial; in the paper we gave the detailed derivation of solving the target function and also a strict proof of its convergence, which is a key contribution of the paper. Compared with sparseness constrained NMF and GNMF algorithms, GRNMF_SC can learn much sparser representation of the data and can also preserve the geometrical structure of the data, which endow it with powerful discriminating ability. Furthermore, the GRNMF_SC is generalized as supervised and unsupervised models to meet different demands. Experimental results demonstrate encouraging results of GRNMF_SC on image recognition and clustering when comparing with the other state-of-the-art NMF methods.

  13. A economia continental chinesa e seu efeito gravitacional

    Directory of Open Access Journals (Sweden)

    Diego Pautasso

    2011-11-01

    Full Text Available O presente artigo aborda o desenvolvimento nacional e a inserção internacional da China. O objetivo é discutir como a formação de uma economia continental na China tem se transformado num fator de projeção desse país no sistema internacional, analisando como a formação de uma economia continental produz uma espécie de efeito gravitacional favorecendo a formulação da estratégia internacional chinesa nesta conjuntura de transição sistêmica. O artigo desenvolve-se discutindo com análises recorrentes sobre o processo de desenvolvimento e de inserção da internacional da China. O argumento central defendido no artigo é que o desenvolvimento da economia continental e a ampliação da capacidade econômica tornam-se um instrumento da política externa chinesa. Em outras palavras, a China tende a criar um forte efeito gravitacional em escala global e utilizar-se disso como parte de sua estratégia internacional. O artigo organiza-se da seguinte forma: na primeira parte, discorremos sobre a evolução recente do desenvolvimento chinês, centrando foco nos desafios da formação de uma economia de dimensões continentais; na segunda, abordamos como o incremento da capacidade econômica chinesa implica num crescente efeito gravitacional do país em escala global; por fim, argumentamos que a diplomacia da China utiliza-se dessas prerrogativas (capacidade econômica para desencadear uma estratégia internacional que permita ao país, nesse quadro de transição sistêmica, ampliar seu espaço de atuação internacional buscando as linhas de menor resistência.

  14. Efeito protetor do aleitamento materno contra a obesidade infantil

    Directory of Open Access Journals (Sweden)

    Balaban Geni

    2004-01-01

    Full Text Available OBJETIVO: Apresentar uma revisão da literatura sobre a hipótese de que o aleitamento materno teria um efeito protetor contra a obesidade infantil, a plausibilidade biológica dessa hipótese e os mecanismos potencialmente envolvidos. FONTES DOS DADOS: Informações coletadas a partir de artigos publicados em revistas científicas indexadas, livros e teses de pós-graduação. A maioria dos artigos foi identificada a partir das bases de dados MEDLINE e Scielo, usando as palavras-chave "aleitamento materno", "sobrepeso", "obesidade", "crianças" e "adolescentes". O período pesquisado foi de 1980 a 2002. Outros artigos foram identificados a partir das referências bibliográficas citadas nos primeiros artigos. SÍNTESE DOS DADOS: A maioria dos estudos revisados relatou um efeito protetor do aleitamento materno contra a obesidade infantil; alguns estudos não encontraram associação entre aleitamento materno e obesidade; um estudo, com um pequeno tamanho amostral, relatou maior adiposidade entre as crianças que receberam aleitamento materno. Diferentes definições de exposição e desfecho dificultam a comparação entre os estudos. Imprinting metabólico foi sugerido como um mecanismo potencialmente envolvido para explicar a associação. Aspectos comportamentais também podem estar envolvidos. CONCLUSÃO: O aleitamento materno parece ter um efeito protetor contra a obesidade infantil, porém essa questão merece uma investigação mais aprofundada.

  15. Efeitos colaterais do metilfenidato Side effects of methylphenidate

    Directory of Open Access Journals (Sweden)

    Giuseppe Pastura

    2004-01-01

    Full Text Available OBJETIVOS: Revisar os principais efeitos colaterais do metilfenidato, em curto e longo prazos, no tratamento de crianças com Transtorno do Déficit de Atenção (TDAH. FONTES DE DADOS: Revisão de literatura nos últimos doze anos através de pesquisa no Medline e Lilacs. RESULTADOS: Dentre os efeitos colaterais que surgem em curto prazo, prevalecem a redução de apetite, insônia, cefaléia e dor abdominal, sendo a maioria autolimitada, dose-dependente e de média intensidade. Dentre aqueles em longo prazo, são descritas alterações discretas de pressão arterial e freqüência cardíaca e uma possível discreta diminuição da estatura. O abuso e a dependência ao medicamento são observados muito raramente. CONCLUSÕES: O perfil de efeitos colaterais do metilfenidato é seguro, não parecendo justificar o seu uso constrito no Brasil, ante os benefícios robustos amplamente demonstrados na literatura.OBJECTIVE: To review main short-term and long-term side effects of methylphenidate in the treatment of Attention-Deficit Disorder in children. SOURCE OF DATA: a 12-year review in Medline and Lilacs. RESULTS: Among those side effects showed in the short-term, anorexia, insomnia, headache and abdominal pain are the most common ones, being the majority self-limited, dose-dependent and of medium intensity. Long-term side effects consist of mild blood pressure and heart rate increase and possible light growth suppression effect. Abuse and dependency are very rare. CONCLUSIONS: Methylphenidate side effects profile is safe and does not seem to justify its restricted use in Brazil, considering its solid benefits widely demonstrated in literature.

  16. Compreendendo o Efeito Placebo / Understanding the Placebo Effect

    Directory of Open Access Journals (Sweden)

    Elayne Vieira Dias

    2015-12-01

    Full Text Available Placebo é definido em termos farmacológicos como uma substância inerte, sem propriedades farmacológicas intrínsecas. No entanto, essa definição é superficial, visto que o placebo pode gerar efeitos terapêuticos que dependem de diversos fatores como palavras, rituais, símbolos e significados que acompanham seu uso. Assim, o efeito placebo não diz respeito apenas a uma substância, mas, envolve fatores cognitivos, genéticos e mecanismos de aprendizagem implícita e explícita. Nessa revisão nós abordamos os aspectos gerais do efeito placebo apoiados em diversos estudos com diferentes enfoques, visando uma melhor compreensão desse fenômeno que pode se somar ao tratamento ativo e otimizar os resultados na prática médica. Placebo is pharmacologically defined as an inert substance, with nointrinsic pharmacological properties. However, this is a superficial definition, since placebo may trigger therapeutic effects and its effectiveness depends on various factors such as words, rituals, symbols and meanings following its use. Thus, placebo effect does not refer just to the substance, but it also involves cognitive and genetic factors and learning mechanisms. Here, we review general aspects of the placebo effect supported by several studies with different approaches, to better understand this phenomenon which may contribute to active treatment as well as optimize the results in the clinical practice.

  17. O efeito obsceno The obscene effect

    Directory of Open Access Journals (Sweden)

    Eliane Robert Moraes

    2003-01-01

    Full Text Available Este artigo investiga a importância do vocabulário obsceno no interior da cultura pornográfica que se inaugura na Europa a partir do Renascimento, cuja pedra de toque é a nomeação explícita do sexo. Para tanto, interroga o estatuto da moderna ficção erótica enquanto gênero literário, atentando para a condição de fetiche da linguagem licenciosa. Representação privilegiada do erotismo, a palavra obscena subverte sua função abstrata de signo para ganhar um corpo próprio que, no limite, substitui a presença do corpo real.This article investigates the importance of obscene vocabulary within the pornographic culture that arises in Europe from the Renaissance onwards, with the explicit wording of sex as a landmark. Therefore, it questions the statute of modern erotic fiction as a literary genre, paying attention to the fetischised conditon of licencious language. A privileged representation of eroticism, obscene words subvert their abstract function as a sign and acquire a corporality that, ultimately, substitute the presence of the real body.

  18. Efeito colateral da quimioterapia e o papel da enfermagem

    OpenAIRE

    Lopes Matoso, Leonardo Magela; Universidade Potiguar - UnP, Campus Mossoró.; Duarte De Rosário, Sâmara Sirdenia; Universidade do Rio Grande do Norte (UERN).

    2014-01-01

    O objetivo deste artigo é avaliar a partir da percepção das mulheres que realizam quimioterapia, as estratégias de cuidados utilizadas pela equipe de enfermagem na redução e/ou alívio dos efeitos colaterais causados pelo tratamento quimioterápico. Trata-se de um estudo de natureza descritiva, exploratória, com abordagem predominantemente qualitativa. A coleta de dados ocorreu no período de novembro a dezembro de 2012, através de um roteiro de entrevista semiestruturado. Os dados qualitativos ...

  19. Efeitos do exercicio agudo sobre biomarcadores sericos de ratos diabeticos

    OpenAIRE

    Milioni, Fabio; Antunes, Barbara De Moura Mello; Teixeira-Arroyo, Claudia; Loures, Joao Paulo; Scariot, Pedro Paulo Menezes; Santos, Paulo Cezar Rocha dos; Silva, Maria Souza; Luciano,Eliete

    2014-01-01

    INTRODUÇÃO: As respostas ao exercício agudo dos biomarcadores, como a fosfatase alcalina (FA) e a creatina quinase (CK) séricas têm sido pouco investigadas em ratos diabéticos. OBJETIVOS: Verificar os efeitos do exercício físico aeróbio agudo sobre as concentrações de CK e FA, bem como, avaliar o estado hídrico em ratos diabéticos experimentais. MATERIAIS E MÉTODOS Foram utilizados ratos Wistar machos, adultos jovens, distribuídos em dois grupos: diabéticos (DA) e controles (CA). O d...

  20. Efeitos da sinvastatina em modelo de osteoartrite em ratos

    OpenAIRE

    Castro, Gláucio Ricardo Werner de

    2009-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pos-Graduação em Farmacologia, Florianópolis, 2009. A osteoartrite é uma doença articular degenerativa, progressiva e irreversível para a qual não há, atualmente, alternativas terapêuticas eficazes. O objetivo do presente estudo foi investigar se o tratamento com sinvastatina poderia exercer efeitos sobre a evolução e os sintomas da osteoartrite. Para tanto, foi utilizado o modelo de...

  1. Treino especializado ou integrado? O efeito da variabilidade no karate

    OpenAIRE

    Pinho, Joana Filipa Simões

    2016-01-01

    Este estudo analisou o efeito da variabilidade no karate pretendendo: 1) obter e comparar dados cinéticos e cinemáticos, do mawashi geri, em adultos e crianças de dois grupos que treinam com diferentes percentagens de treino especializado e integrado, identificando possíveis diferenças entre eles; 2) obter uma avaliação de cada criança, por parte de árbitros nacionais, de modo a comparar os resultados dessa avaliação com o desempenho laboratorial; avaliando também o grau de concordância dos á...

  2. O EFEITO CHAMARIZ NAS DECISÕES DE INVESTIMENTO

    Directory of Open Access Journals (Sweden)

    César Augusto Tibúrcio Silva

    2012-03-01

    Full Text Available O estudo das fi nanças comportamentais vem ganhando destaque e sendo objeto de diversos trabalhos acadêmicos. Muitos conceitos tradicionais de economia, sobre o homem econômico, têm sido questionados, ao se considerarem aspectos observados na prática. Principalmente, a partir dos modernos estudos de economia comportamental, aponta-se que o homem se comporta de maneira enviesada e irracional, para tomar suas decisões. É infl uenciado por detalhes que podem levá-lo a fazer escolhas menos vantajosas, relacionadas ao seu dinheiro, e nem mesmo se dar conta disso. O efeito chamariz refere-se à infl uência que um item, a ser escolhido, exerce sobre aqueles que farão uma escolha, inclusive levando- os a tomar uma decisão que, anteriormente, era duvidosa, ou até mesmo a mudar uma escolha anterior. Esse efeito mostra como o homem cria falsas bases de comparação, para simplifi car um ambiente de escolha entre opções. O trabalho faz uma pesquisa sobre uma decisão de investimento, em que há duas situações, com a presença ou não de um chamariz, algo que pode infl uenciar a decisão fi nal dos investidores. Participaram da pesquisa 386 alunos de graduação do curso de Ciências Contábeis, de cinco universidades, do Distrito Federal. Os alunos foram considerados investidores capazes de analisar índices de liquidez e de julgar qual seria a melhor opção para investir. Viu-se que as pessoas se sentem incentivadas a investir em empresas nas quais foi criada uma falsa base de comparação, pela presença do chamariz. Esse efeito é observado com maior intensidade em alguns grupos específi cos de investidores. Sugere-se a elaboração de novas pesquisas na área, com o objetivo de observar esse efeito em outras situações e de divulgar o estudo das fi nanças comportamentais.

  3. Efeitos da acupuntura no tratamento da ansiedade: revisao integrativa

    OpenAIRE

    Goyatá, Sueli Leiko Takamatsu; Avelino, Carolina Costa Valcanti; Santos, Sérgio Valverde Marques dos; Souza Junior, Deusdete Inácio de; Gurgel, Maria Dorise Simão Lopes; Terra, Fábio de Souza

    2016-01-01

    RESUMO Objetivo: avaliar as evidências científicas disponíveis na literatura sobre os efeitos da acupuntura no tratamento da ansiedade e a qualidade desses estudos. Método: revisão integrativa, realizada nas bases/bancos de dados CINAHL, LILACS, PUBMEDPICO, SciELO, The Cochrane Library, no período entre 2001 a 2014. Os descritores anxiety, acupuncture therapy, acupuncture e anxiety disorders foram combinados entre si para garantir a ampla busca de estudos primários. Resultados: dos 514 art...

  4. Least Square Regularized Regression for Multitask Learning

    Directory of Open Access Journals (Sweden)

    Yong-Li Xu

    2013-01-01

    hypothesis space being the union of a sequence of Hilbert spaces. The algorithm consists of two steps of selecting the optimal Hilbert space and searching for the optimal function. We assume that the distributions of different tasks are related to a set of transformations under which any Hilbert space in the hypothesis space is norm invariant. We prove that under the above assumption the optimal prediction function of every task is in the same Hilbert space. Based on this result, a pivotal error decomposition is founded, which can use samples of related tasks to bound excess error of the target task. We obtain an upper bound for the sample error of related tasks, and based on this bound, potential faster learning rates are obtained compared to single-task learning algorithms.

  5. Application of an adaptive acquisition regularization parameter based on an improved GCV criterion in pre-stack AVO inversion

    Science.gov (United States)

    Huang, Guangtan; Chen, Xiaohong; Li, Jingye; Luo, Cong; Wang, Benfeng

    2017-02-01

    In exploration geophysics, AVO inversion is undoubtedly the most common inverse problem which is ill-posed and must be regularized. Once regularization is used, the selection of the regularization parameter will become an important problem to solve. In practice, the proper regularization parameter value is usually data dependent and determined empirically. For one work area, inversion engineers often give a fixed parameter. In such a case, the results of AVO inversion will be accompanied by strong artificial subjective factors. Besides, it is difficult to guarantee that the fixed parameter could be applied to each trace of the seismic data. In this paper, we first emphasize the importance of the regularization parameter selection for the inverse problems. Then, based on a traditional GCV function, we propose an adaptive acquisition regularization parameter method which can be used in regularization for arbitrary norm conditions, and derive the theoretical formula of the adaptive computation of the regularization parameter. Applying this method to the AVO inversion of synthetic data and field data, we have found that the improved GCV method has better accuracy and robustness than the traditional method.

  6. Bio-inspired Artificial Intelligence: А Generalized Net Model of the Regularization Process in MLP

    Directory of Open Access Journals (Sweden)

    Stanimir Surchev

    2013-10-01

    Full Text Available Many objects and processes inspired by the nature have been recreated by the scientists. The inspiration to create a Multilayer Neural Network came from human brain as member of the group. It possesses complicated structure and it is difficult to recreate, because of the existence of too many processes that require different solving methods. The aim of the following paper is to describe one of the methods that improve learning process of Artificial Neural Network. The proposed generalized net method presents Regularization process in Multilayer Neural Network. The purpose of verification is to protect the neural network from overfitting. The regularization is commonly used in neural network training process. Many methods of verification are present, the subject of interest is the one known as Regularization. It contains function in order to set weights and biases with smaller values to protect from overfitting.

  7. AN IMPLICIT REGULARIZATION FOR 3D BUILDING ROOFTOP MODELING USING AIRBORNE LIDAR DATA

    Directory of Open Access Journals (Sweden)

    G. Sohn

    2012-07-01

    Full Text Available This paper proposes a new algorithm to generalize noisy polylines comprising a rooftop model by maximizing a shape regularity (orthogonality, symmetricity and directional simplications. The nature of remotely sensed data including airborne LiDAR often produce errors in localizing salient features (corners, lines and planes due to weak contrast, occlusions, shadows and object complexity. A generalization or regularization process is well known algorithm for eliminating erroneous vertices while preserving significant information on rooftop shapes. Most of existing regularization methods achieves this goal base on a local process such as if-then rules due to lacking global objective functions or mainly focusing on minimising residuals between boundary observations and models. In this study, we implicitly derive rules to generate local hypothetical models. Those hypothesized models produce possible drawings of regular patterns that given rooftop vectors can possibly generate by combining global and local analysis of line directions and their connections. A final optimal model is globally selected through a gradient descent optimization. A BSP (Binary Tree Partitioning-tree was used to produce initial rooftop vectors using ISPRS WGIII/4's benchmarking test sites in Veihngen. The proposed regularization algorithm was applied to reduce modelling errors produced by BSP-tree. An evaluation demonstrates the proposed algorithm is promising for updating of building database.

  8. Feature selection and multi-kernel learning for adaptive graph regularized nonnegative matrix factorization

    KAUST Repository

    Wang, Jim Jing-Yan

    2014-09-20

    Nonnegative matrix factorization (NMF), a popular part-based representation technique, does not capture the intrinsic local geometric structure of the data space. Graph regularized NMF (GNMF) was recently proposed to avoid this limitation by regularizing NMF with a nearest neighbor graph constructed from the input data set. However, GNMF has two main bottlenecks. First, using the original feature space directly to construct the graph is not necessarily optimal because of the noisy and irrelevant features and nonlinear distributions of data samples. Second, one possible way to handle the nonlinear distribution of data samples is by kernel embedding. However, it is often difficult to choose the most suitable kernel. To solve these bottlenecks, we propose two novel graph-regularized NMF methods, AGNMFFS and AGNMFMK, by introducing feature selection and multiple-kernel learning to the graph regularized NMF, respectively. Instead of using a fixed graph as in GNMF, the two proposed methods learn the nearest neighbor graph that is adaptive to the selected features and learned multiple kernels, respectively. For each method, we propose a unified objective function to conduct feature selection/multi-kernel learning, NMF and adaptive graph regularization simultaneously. We further develop two iterative algorithms to solve the two optimization problems. Experimental results on two challenging pattern classification tasks demonstrate that the proposed methods significantly outperform state-of-the-art data representation methods.

  9. A new regularity-based algorithm for characterizing heterogeneities from digitized core image

    Science.gov (United States)

    Gaci, Said; Zaourar, Naima; Hachay, Olga

    2014-05-01

    The two-dimensional multifractional Brownian motion (2D-mBm) is receiving an increasing interest in image processing. However, one difficulty inherent to this fractal model is the estimation of its local Hölderian regularity function. In this paper, we suggest a new estimator of the local Hölder exponent of 2D-mBm paths. The suggested algorithm has been first tested on synthetic 2D-mBm paths, then implemented on digitized image data of a core extracted from an Algerian borehole. The obtained regularity map shows a clear correlation with the geological features observed on the investigated core. These lithological discontinuities are reflected by local variations of the Hölder exponent value. However, no clear relationship can be drawn between regularity and digitized data. To conclude, the suggested algorithm may be a powerful tool for exploring heterogeneities from core images using the regularity exponents. Keywords: core image, two-dimensional multifractional Brownian motion, fractal, regularity.

  10. Feature extraction using regular expression in detecting proper ...

    African Journals Online (AJOL)

    Feature extraction using regular expression in detecting proper noun for Malay news articles based on KNN algorithm. S Sulaiman, R.A. Wahid, F Morsidi. Abstract. No Abstract. Keywords: data mining; named entity recognition; regular expression; natural language processing. Full Text: EMAIL FREE FULL TEXT EMAIL ...

  11. Chimeric mitochondrial peptides from contiguous regular and swinger RNA

    Directory of Open Access Journals (Sweden)

    Hervé Seligmann

    2016-01-01

    Full Text Available Previous mass spectrometry analyses described human mitochondrial peptides entirely translated from swinger RNAs, RNAs where polymerization systematically exchanged nucleotides. Exchanges follow one among 23 bijective transformation rules, nine symmetric exchanges (X ↔ Y, e.g. A ↔ C and fourteen asymmetric exchanges (X → Y → Z → X, e.g. A → C → G → A, multiplying by 24 DNA's protein coding potential. Abrupt switches from regular to swinger polymerization produce chimeric RNAs. Here, human mitochondrial proteomic analyses assuming abrupt switches between regular and swinger transcriptions, detect chimeric peptides, encoded by part regular, part swinger RNA. Contiguous regular- and swinger-encoded residues within single peptides are stronger evidence for translation of swinger RNA than previously detected, entirely swinger-encoded peptides: regular parts are positive controls matched with contiguous swinger parts, increasing confidence in results. Chimeric peptides are 200× rarer than swinger peptides (3/100,000 versus 6/1000. Among 186 peptides with >8 residues for each regular and swinger parts, regular parts of eleven chimeric peptides correspond to six among the thirteen recognized, mitochondrial protein-coding genes. Chimeric peptides matching partly regular proteins are rarer and less expressed than chimeric peptides matching non-coding sequences, suggesting targeted degradation of misfolded proteins. Present results strengthen hypotheses that the short mitogenome encodes far more proteins than hitherto assumed. Entirely swinger-encoded proteins could exist.

  12. Maximal regularity for non-autonomous stochastic evolution ...

    Indian Academy of Sciences (India)

    Tôn Vi?t T?

    2017-11-17

    Nov 17, 2017 ... We construct unique strict solutions to the equation and show their maximal regularity. The abstract results are then applied to a stochastic partial differential equation. Keywords. Evolution operators; stochastic linear evolution equations; strict solutions; maximal regularity; UMD Banach spaces of type 2.

  13. 39 CFR 3010.7 - Schedule of regular rate changes.

    Science.gov (United States)

    2010-07-01

    ... of mailers of each class of mail in developing the schedule. (e) Whenever the Postal Service deems it... 39 Postal Service 1 2010-07-01 2010-07-01 false Schedule of regular rate changes. 3010.7 Section... PRODUCTS General Provisions § 3010.7 Schedule of regular rate changes. (a) The Postal Service shall...

  14. Analytic regularization of the Yukawa model at finite temperature

    CERN Document Server

    Malbouisson, A P C; Svaiter, N F

    1996-01-01

    We analyse the one-loop fermionic contribution for the scalar effective potential in the temperature dependent Yukawa model. In order to regularize the model a mix between dimensional and analytic regularization procedures is used. We find a general expression for the fermionic contribution in arbitrary spacetime dimension. It is found that in D=3 this contribution is finite.

  15. Degree-regular triangulations of torus and Klein bottle

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    torial 2-manifolds are the boundaries of the tetrahedron, the octahedron, the icosahedron and the 6-vertex real projective plane [4, 5]. The combinatorial manifolds T3,3,0 and T6,2,2. (in Examples 2 and 3) are combinatorially regular. Schulte and Wills [10, 11] have con- structed two combinatorially regular triangulations of ...

  16. Inclusion Professional Development Model and Regular Middle School Educators

    Science.gov (United States)

    Royster, Otelia; Reglin, Gary L.; Losike-Sedimo, Nonofo

    2014-01-01

    The purpose of this study was to determine the impact of a professional development model on regular education middle school teachers' knowledge of best practices for teaching inclusive classes and attitudes toward teaching these classes. There were 19 regular education teachers who taught the core subjects. Findings for Research Question 1…

  17. On the Generating Power of Regularly Controlled Bidirectional Grammars

    NARCIS (Netherlands)

    Asveld, P.R.J.; Hogendorp, J.A.; Hogendorp, J.A.

    1991-01-01

    RCB-grammars or regularly controlled bidirectional grammars are context-free grammars of which the rules can be used in a productive and in a reductive fashion. In addition, the application of these rules is controlled by a regular language. Several modes of derivation can be distinguished for this

  18. On the Generating Power of Regularly Controlled Bidirectional Grammars

    NARCIS (Netherlands)

    Asveld, P.R.J.; Hogendorp, Jan Anne

    1989-01-01

    RCB-grammars or regularly controlled bidirectional grammars are context-free grammars of which the rules can be used in a productive and in a reductive fashion. In addition, the application of these rules is controlled by a regular language. Several modes of derivation can be distinguished for this

  19. Analysis of Logic Programs Using Regular Tree Languages

    DEFF Research Database (Denmark)

    Gallagher, John Patrick

    2012-01-01

    The eld of nite tree automata provides fundamental notations and tools for reasoning about set of terms called regular or recognizable tree languages. We consider two kinds of analysis using regular tree languages, applied to logic programs. The rst approach is to try to discover automatically...

  20. Strictly-regular number system and data structures

    DEFF Research Database (Denmark)

    Elmasry, Amr Ahmed Abd Elmoneim; Jensen, Claus; Katajainen, Jyrki

    2010-01-01

    We introduce a new number system that we call the strictly-regular system, which efficiently supports the operations: digit-increment, digit-decrement, cut, concatenate, and add. Compared to other number systems, the strictly-regular system has distinguishable properties. It is superior to the re...

  1. Efeito da quercetina nas atividades fosfatasicas e seu efeito protetor na hepatotoxicidade induzida pelo acetaminofeno em camundongos

    OpenAIRE

    Camila de Andrade Camargo

    2007-01-01

    Resumo: Os flavonóides são fitocompostos polifenólicos, caracterizados quimicamente como heterosídeos flavônicos. Apresentam diversas atividades biológicas devido às suas propriedades antioxidantes e habilidades em modular a atividade de diversas enzimas ou receptores celulares, tornando-os responsáveis pelo efeito protetor contra doenças relacionadas ao sistema cardiovascular; certas formas de câncer e doenças de fotossensibilidade e envelhecimento. As fosfatases ácidas, enzimas que hidrolis...

  2. Laplacian manifold regularization method for fluorescence molecular tomography

    Science.gov (United States)

    He, Xuelei; Wang, Xiaodong; Yi, Huangjian; Chen, Yanrong; Zhang, Xu; Yu, Jingjing; He, Xiaowei

    2017-04-01

    Sparse regularization methods have been widely used in fluorescence molecular tomography (FMT) for stable three-dimensional reconstruction. Generally, ℓ1-regularization-based methods allow for utilizing the sparsity nature of the target distribution. However, in addition to sparsity, the spatial structure information should be exploited as well. A joint ℓ1 and Laplacian manifold regularization model is proposed to improve the reconstruction performance, and two algorithms (with and without Barzilai-Borwein strategy) are presented to solve the regularization model. Numerical studies and in vivo experiment demonstrate that the proposed Gradient projection-resolved Laplacian manifold regularization method for the joint model performed better than the comparative algorithm for ℓ1 minimization method in both spatial aggregation and location accuracy.

  3. Efeitos da acupuntura no tratamento da ansiedade: revisao integrativa

    Directory of Open Access Journals (Sweden)

    Sueli Leiko Takamatsu Goyatá

    2016-06-01

    Full Text Available RESUMO Objetivo: avaliar as evidências científicas disponíveis na literatura sobre os efeitos da acupuntura no tratamento da ansiedade e a qualidade desses estudos. Método: revisão integrativa, realizada nas bases/bancos de dados CINAHL, LILACS, PUBMEDPICO, SciELO, The Cochrane Library, no período entre 2001 a 2014. Os descritores anxiety, acupuncture therapy, acupuncture e anxiety disorders foram combinados entre si para garantir a ampla busca de estudos primários. Resultados: dos 514 artigos, 67 foram selecionados para leitura na íntegra e 19 incluídos. Desses, 11 apresentaram forte nível de evidência. Dos seis artigos de estudos clínicos randomizados, cinco apresentaram qualidade classificada como razoável. Dois estudos utilizaram acupunturistas enfermeiros para a aplicação da intervenção. Os resultados mostram efeitos positivos e estatisticamente significativos do uso da acupuntura para tratamento de indivíduos com ansiedade. Conclusão: a acupuntura parece ser um tratamento promissor para a ansiedade, no entanto, há necessidade de melhorar a qualidade metodológica das pesquisas nessa temática.

  4. Efeitos das células tronco adultas de medula óssea e do plasma rico em plaquetas na regeneração e recuperação funcional nervosa em um modelo de defeito agudo em nervo perfiférico em rato Bone marrow and platelet-rich plasma stem cells effects on nervous regeneration and functional recovery in an acute defect model of rats' peripheral nerve

    Directory of Open Access Journals (Sweden)

    Jefferson Braga-Silva

    2006-01-01

    Full Text Available OBJETIVOS: Foram avaliados os efeitos do uso de células tronco da medula óssea (CTM e do plasma rico em plaquetas (PRP na regeneração de nervos periféricos, utilizando um modelo estabelecido de regeneração de nervo ciático em ratos. MÉTODOS: Um defeito nervoso de 10 mm foi reconstruído com a utilização de um tubo de silicone preenchido com CTM, PRP ou ambos. O grupo controle recebeu somente o tubo de silicone. Foi realizado ainda um quinto grupo no qual o intervalo foi reconstruído utilizando o segmento ressecado do nervo. A função motora foi testada seis semanas após a cirurgia utilizando teste de marcha. Após o teste motor, os ratos foram anestesiados, o nervo ciático e o tubo foram ressecados e foi realizada microscopia eletrônica de transmissão. RESULTADOS: A análise quantitativa demonstra uma melhora na recuperação funcional no grupo CTM em comparação com os demais grupos. Regeneração nervosa foi demonstrada no grupo CTM por microscopia eletrônica de trasmissão com uma recuperação praticamente completa da anatomia neural. CONCLUSÃO: Nossos resultados sugerem que o uso de CTM associado com a técnica de tubulização promove uma satisfatória recuperação da função motora e regeneração nervosa.OBJECTIVES: The effects of the use of bone marrow stem cells (MSC and platelet-rich plasma (PRP on peripheral nerves regeneration were assessed by using an established model of sciatic nerve regeneration in rats. METHODS: A 10-mm nervous defect was reconstructed by using a silicone tube filled with MSC, PRP or both. The control group received only the silicone tube. A fifth group was also set, in which the interval was reconstructed by using a dried segment of the nerve. Motor function was tested six weeks after surgery, by means of a gait test. After motor test, the rats were anesthetized, the sciatic nerve and the tube were dried, and the transmission electronic microscopy was performed. RESULTS: The quantitative

  5. POTENSI MAHASISWA REGULAR BLOCK SYSTEM (RBS UNIVERSITAS KANJURUHAN MALANG

    Directory of Open Access Journals (Sweden)

    R. Anastasia Endang Susilawati

    2008-02-01

    Full Text Available Survey conducted to obtain get situation of quadran strategy determine elegibility of increase of maximum expense lecturing of program student of Regular Block System (RBS at institute education of University of Kanjuruhan Unlucky enlisting and active in year of akademic 2006/2007. Used variables shall be as follows: 1 psicografis, 2 social of demography and economics, 3 geografis, 4 benefit, 5 last experience, 6 physical medium, 7 expense, 8 advertisement, 9 word of mouth communication, 10 image of PTS, 11 quality of technical service, 12 quality of functional service, 13 satisfaction of student, and 14 student expectation. Technique data collecting use quesioner which consist of question closed and is open. Obtained to be data to be analysed to descriptive method and SWOT ( strengths, weaknesses, opportunities, threats. Result of survey indicate that University of Kanjuruhan unlucky reside in aggresive strategy ( strength 71.12% and opportunity 71.1% and also strategy diversify ( strength 71.12% and threat 69.8%, hence competent to boost up the expense of maximum study equal to 19.41% made balance to with diversification of program to overcome threats faced in this time and in the future.

  6. Optimization of the Regularization in Background and Foreground Modeling

    Directory of Open Access Journals (Sweden)

    Si-Qi Wang

    2014-01-01

    Full Text Available Background and foreground modeling is a typical method in the application of computer vision. The current general “low-rank + sparse” model decomposes the frames from the video sequences into low-rank background and sparse foreground. But the sparse assumption in such a model may not conform with the reality, and the model cannot directly reflect the correlation between the background and foreground either. Thus, we present a novel model to solve this problem by decomposing the arranged data matrix D into low-rank background L and moving foreground M. Here, we only need to give the priori assumption of the background to be low-rank and let the foreground be separated from the background as much as possible. Based on this division, we use a pair of dual norms, nuclear norm and spectral norm, to regularize the foreground and background, respectively. Furthermore, we use a reweighted function instead of the normal norm so as to get a better and faster approximation model. Detailed explanation based on linear algebra about our two models will be presented in this paper. By the observation of the experimental results, we can see that our model can get better background modeling, and even simplified versions of our algorithms perform better than mainstream techniques IALM and GoDec.

  7. Noncovalent Interactions between Dopamine and Regular and Defective Graphene.

    Science.gov (United States)

    Fernández, Ana C Rossi; Castellani, Norberto J

    2017-08-05

    The role of noncovalent interactions in the adsorption of biological molecules on graphene is a subject of fundamental interest regarding the use of graphene as a material for sensing and drug delivery. The adsorption of dopamine on regular graphene and graphene with monovacancies (GV) is theoretically studied within the framework of density functional theory. Several adsorption modes are considered, and notably those in which the dopamine molecule is oriented parallel or quasi-parallel to the surface are the more stable. The adsorption of dopamine on graphene implies an attractive interaction of a dispersive nature that competes with Pauli repulsion between the occupied π orbitals of the dopamine ring and the π orbitals of graphene. If dopamine adsorbs at the monovacancy in the A-B stacking mode, a hydrogen bond is produced between one of the dopamine hydroxy groups and one carbon atom around the vacancy. The electronic charge redistribution due to adsorption is consistent with an electronic drift from the graphene or GV surface to the dopamine molecule. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. High-order regularization in lattice-Boltzmann equations

    Science.gov (United States)

    Mattila, Keijo K.; Philippi, Paulo C.; Hegele, Luiz A.

    2017-04-01

    A lattice-Boltzmann equation (LBE) is the discrete counterpart of a continuous kinetic model. It can be derived using a Hermite polynomial expansion for the velocity distribution function. Since LBEs are characterized by discrete, finite representations of the microscopic velocity space, the expansion must be truncated and the appropriate order of truncation depends on the hydrodynamic problem under investigation. Here we consider a particular truncation where the non-equilibrium distribution is expanded on a par with the equilibrium distribution, except that the diffusive parts of high-order non-equilibrium moments are filtered, i.e., only the corresponding advective parts are retained after a given rank. The decomposition of moments into diffusive and advective parts is based directly on analytical relations between Hermite polynomial tensors. The resulting, refined regularization procedure leads to recurrence relations where high-order non-equilibrium moments are expressed in terms of low-order ones. The procedure is appealing in the sense that stability can be enhanced without local variation of transport parameters, like viscosity, or without tuning the simulation parameters based on embedded optimization steps. The improved stability properties are here demonstrated using the perturbed double periodic shear layer flow and the Sod shock tube problem as benchmark cases.

  9. Entropic Regularization to Assist a Geologist in Producing a Geologic Map

    Directory of Open Access Journals (Sweden)

    Francisco S. Oliveira

    2011-04-01

    Full Text Available The gravity and magnetic data measured on the Earth’s surface or above it (collected from an aircraft flying at low altitude can be used to assist in geologic mapping by estimating the spatial density and magnetization distributions, respectively, presumably confined to the interior of a horizontal slab with known depths to the top and bottom. To estimate density or magnetization distributions we assume a piecewise constant function defined on a user-specified grid of cells and invert the gravity or magnetic data by using the entropic regularization as a stabilizing function that allows estimating abrupt changes in the physical-property distribution. The entropic regularization combines the minimization of the first-order entropy measure with the maximization of the zeroth-order entropy measure of the solution vector. The aim of this approach is to detect sharp-bounded geologic units through the discontinuities in the estimated density or magnetization distributions. Tests conducted with synthetic data show that the entropic regularization can delineate discontinuous geologic units, allowing a better mapping of sharp-bounded (but buried geologic bodies. We demonstrate the potential of the entropic regularization to assist a geologist in obtaining a geologic map by analyzing the estimated magnetization distributions from field magnetic data over a magnetic skarn in Butte Valley, Nevada, U.S.A. We show that it is an exoskarn where the ion exchange between the intrusive and the host rock occurs along a limited portion of the southern intrusive border.

  10. General Regularities of Wood Surface Roughness

    Directory of Open Access Journals (Sweden)

    MAGOSS, Endre

    2008-01-01

    Full Text Available The surface roughness of wood products is depending on many factors related both towood properties and wood working operational parameters. Probably this is the reason why there areno generally valid correlation determining surface roughness parameters as a function of influencingfactors. In particular, the account of wood structure in the surface roughness interpretation proved tobe difficult.In the last years an important progress was made in recognizing the role of the anatomicalstructure of wood species in the attainable surface roughness. The introduction of a structure numbermade it possible to express and characterize the different wood species numerically.The aim of these studies was the separation of roughness components due to the anatomicalstructure and the woodworking operation. Using a special finishing technique, the roughnesscomponent due to woodworking operations was not significant and could be separated. The samespecimens were also subjected to different woodworking operations using cutting velocities between10 and 50 m/s. The processing of experimental data resulted in a chart showing the minimumroughness component due to different woodworking operations. Special experimental investigationwas conducted to clear the influence of edge dullness on the surface roughness, especially on itsAbbott-parameters. The measurements showed that the Rk-parameter is a good indicator to predictedge dullness.

  11. Learning regularization parameters for general-form Tikhonov

    Science.gov (United States)

    Chung, Julianne; Español, Malena I.

    2017-07-01

    Computing regularization parameters for general-form Tikhonov regularization can be an expensive and difficult task, especially if multiple parameters or many solutions need to be computed in real time. In this work, we assume training data is available and describe an efficient learning approach for computing regularization parameters that can be used for a large set of problems. We consider an empirical Bayes risk minimization framework for finding regularization parameters that minimize average errors for the training data. We first extend methods from Chung et al (2011 SIAM J. Sci. Comput. 33 3132-52) to the general-form Tikhonov problem. Then we develop a learning approach for multi-parameter Tikhonov problems, for the case where all involved matrices are simultaneously diagonalizable. For problems where this is not the case, we describe an approach to compute near-optimal regularization parameters by using operator approximations for the original problem. Finally, we propose a new class of regularizing filters, where solutions correspond to multi-parameter Tikhonov solutions, that requires less data than previously proposed optimal error filters, avoids the generalized SVD, and allows flexibility and novelty in the choice of regularization matrices. Numerical results for 1D and 2D examples using different norms on the errors show the effectiveness of our methods.

  12. Two hybrid regularization frameworks for solving the electrocardiography inverse problem

    Energy Technology Data Exchange (ETDEWEB)

    Jiang Mingfeng; Xia Ling; Shou Guofa; Liu Feng [Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027 (China); Crozier, Stuart [School of Information Technology and Electrical Engineering, University of Queensland, St. Lucia, Brisbane, Queensland 4072 (Australia)], E-mail: xialing@zju.edu.cn

    2008-09-21

    In this paper, two hybrid regularization frameworks, LSQR-Tik and Tik-LSQR, which integrate the properties of the direct regularization method (Tikhonov) and the iterative regularization method (LSQR), have been proposed and investigated for solving ECG inverse problems. The LSQR-Tik method is based on the Lanczos process, which yields a sequence of small bidiagonal systems to approximate the original ill-posed problem and then the Tikhonov regularization method is applied to stabilize the projected problem. The Tik-LSQR method is formulated as an iterative LSQR inverse, augmented with a Tikhonov-like prior information term. The performances of these two hybrid methods are evaluated using a realistic heart-torso model simulation protocol, in which the heart surface source method is employed to calculate the simulated epicardial potentials (EPs) from the action potentials (APs), and then the acquired EPs are used to calculate simulated body surface potentials (BSPs). The results show that the regularized solutions obtained by the LSQR-Tik method are approximate to those of the Tikhonov method, the computational cost of the LSQR-Tik method, however, is much less than that of the Tikhonov method. Moreover, the Tik-LSQR scheme can reconstruct the epcicardial potential distribution more accurately, specifically for the BSPs with large noisy cases. This investigation suggests that hybrid regularization methods may be more effective than separate regularization approaches for ECG inverse problems.

  13. Two hybrid regularization frameworks for solving the electrocardiography inverse problem

    Science.gov (United States)

    Jiang, Mingfeng; Xia, Ling; Shou, Guofa; Liu, Feng; Crozier, Stuart

    2008-09-01

    In this paper, two hybrid regularization frameworks, LSQR-Tik and Tik-LSQR, which integrate the properties of the direct regularization method (Tikhonov) and the iterative regularization method (LSQR), have been proposed and investigated for solving ECG inverse problems. The LSQR-Tik method is based on the Lanczos process, which yields a sequence of small bidiagonal systems to approximate the original ill-posed problem and then the Tikhonov regularization method is applied to stabilize the projected problem. The Tik-LSQR method is formulated as an iterative LSQR inverse, augmented with a Tikhonov-like prior information term. The performances of these two hybrid methods are evaluated using a realistic heart-torso model simulation protocol, in which the heart surface source method is employed to calculate the simulated epicardial potentials (EPs) from the action potentials (APs), and then the acquired EPs are used to calculate simulated body surface potentials (BSPs). The results show that the regularized solutions obtained by the LSQR-Tik method are approximate to those of the Tikhonov method, the computational cost of the LSQR-Tik method, however, is much less than that of the Tikhonov method. Moreover, the Tik-LSQR scheme can reconstruct the epcicardial potential distribution more accurately, specifically for the BSPs with large noisy cases. This investigation suggests that hybrid regularization methods may be more effective than separate regularization approaches for ECG inverse problems.

  14. Three regularities of recognition memory: the role of bias.

    Science.gov (United States)

    Hilford, Andrew; Maloney, Laurence T; Glanzer, Murray; Kim, Kisok

    2015-12-01

    A basic assumption of Signal Detection Theory is that decisions are made on the basis of likelihood ratios. In a preceding paper, Glanzer, Hilford, and Maloney (Psychonomic Bulletin & Review, 16, 431-455, 2009) showed that the likelihood ratio assumption implies that three regularities will occur in recognition memory: (1) the Mirror Effect, (2) the Variance Effect, (3) the normalized Receiver Operating Characteristic (z-ROC) Length Effect. The paper offered formal proofs and computational demonstrations that decisions based on likelihood ratios produce the three regularities. A survey of data based on group ROCs from 36 studies validated the likelihood ratio assumption by showing that its three implied regularities are ubiquitous. The study noted, however, that bias, another basic factor in Signal Detection Theory, can obscure the Mirror Effect. In this paper we examine how bias affects the regularities at the theoretical level. The theoretical analysis shows: (1) how bias obscures the Mirror Effect, not the other two regularities, and (2) four ways to counter that obscuring. We then report the results of five experiments that support the theoretical analysis. The analyses and the experimental results also demonstrate: (1) that the three regularities govern individual, as well as group, performance, (2) alternative explanations of the regularities are ruled out, and (3) that Signal Detection Theory, correctly applied, gives a simple and unified explanation of recognition memory data.

  15. Metabolic effects of regular physical exercise in healthy population.

    Science.gov (United States)

    Caro, Juan; Navarro, Inmaculada; Romero, Pedro; Lorente, Rosario I; Priego, María Antonia; Martínez-Hervás, Sergio; Real, Jose T; Ascaso, Juan F

    2013-04-01

    To assess the effect of moderate regular aerobic physical activity not associated to body weight changes on insulin resistance and the associated metabolic changes in general population. A cross-sectional, observational study in an adult population (n=101 subjects aged 30-70 years) with no personal history of disease and with stable weight in the three months prior to the study. The group with regular exercise performed 30-60 minutes of moderate regular physical exercise 5 days per week (7.5-15 hours MET per week), while a control group performed no regular physical exercise and had a sedentary lifestyle. Subjects were age- and sex-matched. Lipids, lipoproteins, and HOMA index were measured using standard methods. The group with regular physical activity consisted of 48 subjects (21 male/27 female), while the group with no regular physical activity included 53 subjects (31 male/22 female). No significant differences were found between the groups in age, sex, BMI, waist circumference, and blood pressure. Significant differences were found between the groups in fasting serum triglyceride, HDL-C, and apoB levels. Fasting plasma insulin levels (12.1 ± 4.13 vs 14.9 ± 4.8 mU/L, P= .004) and HOMA index (2.8 ± 1.1 vs 3.5 ± 4.1, P= .001) were significantly lower in the group with regular physical activity as compared to the sedentary group. Prevalence rates of metabolic syndrome were 20.7% and 45.8% (P=.01) in the regular physical activity and sedentary groups respectively. Moderate regular physical activity is associated to higher insulin sensitivity, an improved lipid profile, and a decrease in components of metabolic syndrome with no change in weight or BMI. Copyright © 2012 SEEN. Published by Elsevier Espana. All rights reserved.

  16. Produção da cenoura e efeito na fertilidade do solo e nutrição decorrente da solarização do solo para controle da tiririca Carrot production and effect on soil fertility and nutrition as function of soil solarization for purple nutsedge weed control

    Directory of Open Access Journals (Sweden)

    Marta dos Santos Freire Ricci

    2006-01-01

    Full Text Available Dentre os desafios do cultivo orgânico de hortaliças destaca-se o controle de plantas daninhas, devido à proibição do uso de herbicidas. Entre as invasoras, a tiririca (Cyperus rotundus L. é de difícil controle pela sua alta competitividade. A solarização é uma alternativa para desinfestação do solo, a qual consiste em cobri-lo com plástico transparente, com bons resultados no controle da tiririca. A fim de avaliar a influência do preparo e do revolvimento do solo sobre a eficiência da solarização no controle da tiririca, bem como seu posterior efeito sobre o cultivo da cenoura, foi realizado um experimento na Fazendinha Agroecológica, em Seropédica (RJ. O experimento foi disposto em blocos ao acaso com três repetições, em arranjo fatorial 2 x 3 mais uma testemunha adicional, sendo: 1 solo solarizado, preparado (com grade aradora e revolvido 30 dias após a solarização (manualmente com auxílio de uma enxada; 2 solo solarizado, preparado e revolvido aos 60 dias; 3 solo solarizado, preparado e não revolvido; 4 solo solarizado, não preparado e revolvido aos 30 dias; 5 solo solarizado, não preparado e revolvido aos 60 dias; 6 solo solarizado, não preparado e não revolvido; solo não solarizado, não preparado e não revolvido (testemunha. A solarização iniciou-se em 29/1/2002, e durou cem dias. A solarização reduziu em 86% a infestação de tiririca no cultivo da cenoura. Até 10 cm de profundidade, a temperatura do solo foi superior nas parcelas solarizadas, porém a 5 cm, a solarização foi mais eficiente quando associada ao preparo do solo, não havendo efeito do revolvimento. A solarização aumentou os valores da biomassa microbiana e dos teores de Ca, Mg e P do solo. O desenvolvimento da cenoura foi influenciado pela solarização que resultou em maior produtividade.Herbicides are not allowed in organic farming system which turns the control of weeds plants quite difficult during the cultivation of vegetables

  17. Regularization theory for ill-posed problems selected topics

    CERN Document Server

    Lu, Shuai

    2013-01-01

    Thismonograph is a valuable contribution to thehighly topical and extremly productive field ofregularisationmethods for inverse and ill-posed problems. The author is an internationally outstanding and acceptedmathematicianin this field. In his book he offers a well-balanced mixtureof basic and innovative aspects.He demonstrates new,differentiatedviewpoints, and important examples for applications. The bookdemontrates thecurrent developments inthe field of regularization theory,such as multiparameter regularization and regularization in learning theory. The book is written for graduate and PhDs

  18. A regularized GMRES method for inverse blackbody radiation problem

    Directory of Open Access Journals (Sweden)

    Wu Jieer

    2013-01-01

    Full Text Available The inverse blackbody radiation problem is focused on determining temperature distribution of a blackbody from measured total radiated power spectrum. This problem consists of solving a first kind of Fredholm integral equation and many numerical methods have been proposed. In this paper, a regularized GMRES method is presented to solve the linear ill-posed problem caused by the discretization of such an integral equation. This method projects the orignal problem onto a lower dimensional subspaces by the Arnoldi process. Tikhonov regularization combined with GCV criterion is applied to stabilize the numerical iteration process. Three numerical examples indicate the effectiveness of the regularized GMRES method.

  19. Closedness type regularity conditions in convex optimization and beyond

    Directory of Open Access Journals (Sweden)

    Sorin-Mihai Grad

    2016-09-01

    Full Text Available The closedness type regularity conditions have proven during the last decade to be viable alternatives to their more restrictive interiority type counterparts, in both convex optimization and different areas where it was successfully applied. In this review article we de- and reconstruct some closedness type regularity conditions formulated by means of epigraphs and subdifferentials, respectively, for general optimization problems in order to stress that they arise naturally when dealing with such problems. The results are then specialized for constrained and unconstrained convex optimization problems. We also hint towards other classes of optimization problems where closedness type regularity conditions were successfully employed and discuss other possible applications of them.

  20. Bias-Variance Tradeoff of Graph Laplacian Regularizer

    Science.gov (United States)

    Chen, Pin-Yu; Liu, Sijia

    2017-08-01

    This paper presents a bias-variance tradeoff of graph Laplacian regularizer, which is widely used in graph signal processing and semi-supervised learning tasks. The scaling law of the optimal regularization parameter is specified in terms of the spectral graph properties and a novel signal-to-noise ratio parameter, which suggests selecting a mediocre regularization parameter is often suboptimal. The analysis is applied to three applications, including random, band-limited, and multiple-sampled graph signals. Experiments on synthetic and real-world graphs demonstrate near-optimal performance of the established analysis.

  1. Factors distinguishing regular readers of breast cancer information in magazines.

    Science.gov (United States)

    Johnson, J D

    1997-01-01

    This study examined the differences between women who were regular and occasional readers of breast cancer information in magazines. Based on uses and gratifications theory and the Health Belief Model, women respondents (n = 366) were predicted to differentially expose themselves to information. A discriminant analysis showed that women who were regular readers reported greater fear, perceived vulnerability, general health concern, personal experience, and surveillance need for breast cancer-related information. The results are discussed in terms of the potential positive and negative consequences of regular exposure to breast cancer information in magazines.

  2. Directional Total Generalized Variation Regularization for Impulse Noise Removal

    DEFF Research Database (Denmark)

    Kongskov, Rasmus Dalgas; Dong, Yiqiu

    2017-01-01

    A recently suggested regularization method, which combines directional information with total generalized variation (TGV), has been shown to be successful for restoring Gaussian noise corrupted images. We extend the use of this regularizer to impulse noise removal and demonstrate that using...... this regularizer for directional images is highly advantageous. In order to estimate directions in impulse noise corrupted images, which is much more challenging compared to Gaussian noise corrupted images, we introduce a new Fourier transform-based method. Numerical experiments show that this method is more...

  3. Caracterizaciones combinatorias y algebraicas de grafos distancia-regulares

    OpenAIRE

    Fiol Mora, Miquel Àngel

    2013-01-01

    Los grafos distancia-regulares aparecen a menudo en el estudio de es- tructuras matemáticas con un alto grado de simetría y/o regularidad. Un ejemplo bien conocido de tales grafos son los esqueletos de los sólidos platónicos. Desde que fueron propuestos por Norman Biggs, los grafos distancia-regulares han sido caracterizados por numerosos resultados, tanto de carácter combinatorio como algebraico. Como ejemplo del primer caso, sabemos que un grafo es distancia-regular ...

  4. Fuzzy Weak Regular, Strong and Preassociative Filters in Residuated Lattices

    Directory of Open Access Journals (Sweden)

    Wei Yang

    2014-06-01

    Full Text Available In this paper, the notions of fuzzy weak regular, strong and preassociative filters are introduced with some properties of them investigated. In particular, under the context of Glivenko algebras, fuzzy weak regular filters and regular ones are equivalent and characterizations of Glivenko algebras are concluded by characterizations of fuzzy strong filters. At last the notion of fuzzy preassociative filters are defined, which are proved to coincide with fuzzy Boolean filters, and then some new alternative definitions of Boolean algebras are obtained by this type of filters.

  5. Efeito da urina de vaca no estado nutricional da alface

    Directory of Open Access Journals (Sweden)

    Nelson Licínio C. de Oliveira

    2010-08-01

    Full Text Available Existem diversos relatos da utilização da urina de vaca em hortaliças, todavia sua eficácia carece de comprovação. Objetivou-se avaliar o efeito da urina de vaca no estado nutricional da alface. O experimento foi constituído de 12 tratamentos, esquema de parcelas subdivididas, em blocos ao acaso, com quatro repetições. Nas parcelas foram alocadas as vias de aplicação (solo ou foliar e nas subparcelas as concentrações das soluções (0,00; 0,25; 0,50; 0,75; 1,00 e 1,25% v/v. Aplicou-se 60 mL de solução/planta, divididos em cinco aplicações de 5; 5; 10; 20 e 20 mL/planta, aos 7, 14, 21, 28 e 35 após o transplante, respectivamente. Durante o ciclo avaliou-se o índice SPAD e na colheita a massa da matéria seca de cabeça (MSCA e os teores de N, P, K, Ca, Mg, S, Na, Zn, Fe, Mn, Cu e B na matéria seca das folhas (MSF, caule (MSC e raízes (MSR. Em ambas as vias de aplicação o índice SPAD apresentou incremento linear às concentrações e resposta quadrática ao longo do tempo. A MSCA teve comportamento linear às concentrações, com aumento de 25,9 e 35,4% nas aplicações via foliar e solo, respectivamente. Não houve efeito de concentrações sobre teores de nutrientes na MSF e MSC. Na MSR, via solo, os teores de P e K apresentaram pontos de máximo enquanto Fe e Mn de mínimo; o Na apresentou incremento linear às concentrações via foliar. Os efeitos da urina sobre o crescimento da alface provavelmente são devidos a fatores outros que não somente a quantidade de nutrientes veiculados nas soluções.

  6. EFEITO DO REGULADOR DE CRESCIMENTO TRINEXAPAC-ETHYL EM CULTIVARES DE ARROZ IRRIGADO

    OpenAIRE

    Ana Paula Estevo

    2013-01-01

    Este estudo tem por objetivo avaliar os efeitos do regulador de crescimento Trinexapac-ethyl sobre cultivares de arroz irrigado, verificando o efeito de doses crescentes do ingrediente ativo sobre a morfologia de plantas, sobre os componentes do rendimento e sobre a redução de acamamento de cultivar potencialmente acamadora. Neste sentido, dois ensaios foram realizados, um em campo, com o objetivo de avaliar os efeitos de doses e épocas de aplicação do Trinexapac-ethyl sobre os componentes do...

  7. Efeitos cardiopulmonares do treinamento em plataforma vibratória em idosos saudáveis

    OpenAIRE

    PESSOA, Maíra Florentino

    2012-01-01

    A vibração surgiu como forma de treinamento em 1970 e evoluiu para a vibração de corpo inteiro ou Whole Body vibration (WBV), que é aplicada como treinamento e de forma terapêutica, sendo bastante utilizada nos idosos. Por ser um treinamento global, seus efeitos reportam-se a diversos sistemas, tendo efeitos comprovados no ganho de força, na densidade mineral óssea e no equilíbrio de idosos. Entretanto, seus efeitos sobre o sistema cardioplumonar ainda não foram bem documentado...

  8. Tunneling into quantum wires: Regularization of the tunneling Hamiltonian and consistency between free and bosonized fermions

    Science.gov (United States)

    Filippone, Michele; Brouwer, Piet W.

    2016-12-01

    Tunneling between a point contact and a one-dimensional wire is usually described with the help of a tunneling Hamiltonian that contains a δ function in position space. Whereas the leading-order contribution to the tunneling current is independent of the way this δ function is regularized, higher-order corrections with respect to the tunneling amplitude are known to depend on the regularization. Instead of regularizing the δ function in the tunneling Hamiltonian, one may also obtain a finite tunneling current by invoking the ultraviolet cutoffs in a field-theoretic description of the electrons in the one-dimensional conductor, a procedure that is often used in the literature. For the latter case, we show that standard ultraviolet cutoffs lead to different results for the tunneling current in fermionic and bosonized formulations of the theory, when going beyond leading order in the tunneling amplitude. We show how to recover the standard fermionic result using the formalism of functional bosonization and revisit the tunneling current to leading order in the interacting case.

  9. Model-based iterative reconstruction using higher-order regularization of dynamic synchrotron data

    Science.gov (United States)

    Kazantsev, Daniil; Guo, Enyu; Phillion, A. B.; Withers, Philip J.; Lee, Peter D.

    2017-09-01

    We present a novel iterative reconstruction method applied to in situ x-ray synchrotron tomographic data of dendrite formation during the solidification of magnesium alloy. Frequently, fast dynamic imaging projection data are undersampled, noisy, of poor contrast and can contain various acquisition artifacts. Direct reconstruction methods are not suitable and iterative reconstruction techniques must be adapted to the existing data features. Normally, an accurate modelling of the objective function can guarantee a better reconstruction. In this work, we design a special cost function where the data fidelity term is based on the Group-Huber functional to minimize ring artifacts and the regularization term is a higher-order variational penalty. We show that the total variation penalty is unsuitable for some cases and higher-order regularization functionals can ensure a better fit to the expected properties of the data. Additionally, we highlight the importance of 3D regularization over 2D for the problematic data. The proposed method shows a promising performance dealing with angular undersampled noisy dynamic data with ring artifacts.

  10. Space-Dependent Sobolev Gradients as a Regularization for Inverse Radiative Transfer Problems

    Directory of Open Access Journals (Sweden)

    Y. Favennec

    2016-01-01

    Full Text Available Diffuse optical tomography problems rely on the solution of an optimization problem for which the dimension of the parameter space is usually large. Thus, gradient-type optimizers are likely to be used, such as the Broyden-Fletcher-Goldfarb-Shanno (BFGS algorithm, along with the adjoint-state method to compute the cost function gradient. Usually, the L2-inner product is chosen within the extraction procedure (i.e., in the definition of the relationship between the cost function gradient and the directional derivative of the cost function while alternative inner products that act as regularization can be used. This paper presents some results based on space-dependent Sobolev inner products and shows that this method acts as an efficient low-pass filter on the cost function gradient. Numerical results indicate that the use of Sobolev gradients can be particularly attractive in the context of inverse problems, particularly because of the simplicity of this regularization, since a single additional diffusion equation is to be solved, and also because the quality of the solution is smoothly varying with respect to the regularization parameter.

  11. DETERMINISMO MORAL EM HUME: A APOSTA NA REGULARIDADE MORAL DETERMINISM IN HUME: TRUSTING IN REGULARITY

    Directory of Open Access Journals (Sweden)

    Andrea Cachel

    2008-12-01

    Full Text Available Hume, no segundo livro do Tratado e na Investigação acerca do Entendimento Humano, sustenta a posição de que a vontade atua segundo a necessidade e não conforme a liberdade. A filosofia humeana é defensora da existência de uma causa necessária para as ações voluntárias, causa essa que não seria a vontade, como iniciadora da cadeia causal, mas sim algo anterior que a determina na geração de efeitos necessários. Este artigo pretende expor seus argumentos, mostrando como essa temática evidencia a importância que passa a ter a busca por regularidades, o que pretende nos permitir breves reflexões sobre o estatuto conferido por Hume a certas áreas do conhecimento, bem como a respeito do estatuto da própria filosofia humeana. In second book of  the Treatise of Human Nature and also in the book An Enquire concerning Human Understanding, Hume sustain his position that the will act according to necessity, not according to freedom. Humean philosophy defends the existence of a necessary cause to the voluntary human actions, and that this cause is not the will´s own movement, but something prior to it, that establishes the generation of necessary effects. This paper aims to show his arguments and intents to indicate the importance of the search for regularities. Through such examination, we want to develop brief ideas about Hume´s meaning for certain areas of knowledge, as well as for the very meaning of humean philosophy.   Keywords: determinism, human action, regularity, will.  

  12. Bounds on Threshold of Regular Random $k$-SAT

    CERN Document Server

    Rathi, Vishwambhar; Rasmussen, Lars; Skoglund, Mikael

    2010-01-01

    We consider the regular model of formula generation in conjunctive normal form (CNF) introduced by Boufkhad et. al. We derive an upper bound on the satisfiability threshold and NAE-satisfiability threshold for regular random $k$-SAT for any $k \\geq 3$. We show that these bounds matches with the corresponding bound for the uniform model of formula generation. We derive lower bound on the threshold by applying the second moment method to the number of satisfying assignments. For large $k$, we note that the obtained lower bounds on the threshold of a regular random formula converges to the lower bound obtained for the uniform model. Thus, we answer the question posed in \\cite{AcM06} regarding the performance of the second moment method for regular random formulas.

  13. Mini-Stroke vs. Regular Stroke: What's the Difference?

    Science.gov (United States)

    ... How is a ministroke different from a regular stroke? Answers from Jerry W. Swanson, M.D. When ... brain, spinal cord or retina, which may cause stroke-like symptoms but does not damage brain cells ...

  14. BILINGUAL AND REGULAR CLASS STUDENTS’ ATTITUDES TOWARDS ENGLISH

    Directory of Open Access Journals (Sweden)

    Nihta Liando

    2013-01-01

    Full Text Available This article presents the results of the study investigating the relationship between the students’ attitudes towards English and their English achievements in bilingual and regular classes and investigating the differences. The study was conducted in a junior high school in Manado. There are 30 Year VIII students in each bilingual class and each regular class. The results are as follows. First, there is a significant correlation between the students’ attitudes towards English and their achievements. Second, there is a significant difference in their English achievements between bilingual class students and regular students. Third, female students have higher English achievements than male students. Bilingual class students have more positive attitudes and higher English learning achievements than regular class students.

  15. Automatic Constraint Detection for 2D Layout Regularization.

    Science.gov (United States)

    Jiang, Haiyong; Nan, Liangliang; Yan, Dong-Ming; Dong, Weiming; Zhang, Xiaopeng; Wonka, Peter

    2016-08-01

    In this paper, we address the problem of constraint detection for layout regularization. The layout we consider is a set of two-dimensional elements where each element is represented by its bounding box. Layout regularization is important in digitizing plans or images, such as floor plans and facade images, and in the improvement of user-created contents, such as architectural drawings and slide layouts. To regularize a layout, we aim to improve the input by detecting and subsequently enforcing alignment, size, and distance constraints between layout elements. Similar to previous work, we formulate layout regularization as a quadratic programming problem. In addition, we propose a novel optimization algorithm that automatically detects constraints. We evaluate the proposed framework using a variety of input layouts from different applications. Our results demonstrate that our method has superior performance to the state of the art.

  16. Many Under 40 May Not Need Regular Cholesterol Checks

    Science.gov (United States)

    ... gov/news/fullstory_165582.html Many Under 40 May Not Need Regular Cholesterol Checks: Study But heart ... not be available after 08/13/2017) Monday, May 15, 2017 MONDAY, May 15, 2017 (HealthDay News) -- ...

  17. Automatic Constraint Detection for 2D Layout Regularization

    KAUST Repository

    Jiang, Haiyong

    2015-09-18

    In this paper, we address the problem of constraint detection for layout regularization. As layout we consider a set of two-dimensional elements where each element is represented by its bounding box. Layout regularization is important for digitizing plans or images, such as floor plans and facade images, and for the improvement of user created contents, such as architectural drawings and slide layouts. To regularize a layout, we aim to improve the input by detecting and subsequently enforcing alignment, size, and distance constraints between layout elements. Similar to previous work, we formulate the layout regularization as a quadratic programming problem. In addition, we propose a novel optimization algorithm to automatically detect constraints. In our results, we evaluate the proposed framework on a variety of input layouts from different applications, which demonstrates our method has superior performance to the state of the art.

  18. On the Regular Emptiness Problem of Subzero Automata

    Directory of Open Access Journals (Sweden)

    Henryk Michalewski

    2016-08-01

    Full Text Available Subzero automata is a class of tree automata whose acceptance condition can express probabilistic constraints. Our main result is that the problem of determining if a subzero automaton accepts some regular tree is decidable.

  19. A Regularized Algorithm for the Proximal Split Feasibility Problem

    Directory of Open Access Journals (Sweden)

    Zhangsong Yao

    2014-01-01

    Full Text Available The proximal split feasibility problem has been studied. A regularized method has been presented for solving the proximal split feasibility problem. Strong convergence theorem is given.

  20. dental services and attitudes towards its regular utilization among

    African Journals Online (AJOL)

    standardized, pretested and self-administered questionnaire was utilized to elicit responses on dental services ... attitude towards regular dental service utilization and this improved with ... Culture, National Directorate of Employment,. National ...