WorldWideScience

Sample records for regular class 22-26

  1. Regular extensions of some classes of grammars

    NARCIS (Netherlands)

    Nijholt, Antinus

    Culik and Cohen introduced the class of LR-regular grammars, an extension of the LR(k) grammars. In this report we consider the analogous extension of the LL(k) grammers, called the LL-regular grammars. The relations of this class of grammars to other classes of grammars are shown. Every LL-regular

  2. Thermodynamics of a class of regular black holes with a generalized uncertainty principle

    Science.gov (United States)

    Maluf, R. V.; Neves, Juliano C. S.

    2018-05-01

    In this article, we present a study on thermodynamics of a class of regular black holes. Such a class includes Bardeen and Hayward regular black holes. We obtained thermodynamic quantities like the Hawking temperature, entropy, and heat capacity for the entire class. As part of an effort to indicate some physical observable to distinguish regular black holes from singular black holes, we suggest that regular black holes are colder than singular black holes. Besides, contrary to the Schwarzschild black hole, that class of regular black holes may be thermodynamically stable. From a generalized uncertainty principle, we also obtained the quantum-corrected thermodynamics for the studied class. Such quantum corrections provide a logarithmic term for the quantum-corrected entropy.

  3. Class of regular bouncing cosmologies

    Science.gov (United States)

    Vasilić, Milovan

    2017-06-01

    In this paper, I construct a class of everywhere regular geometric sigma models that possess bouncing solutions. Precisely, I show that every bouncing metric can be made a solution of such a model. My previous attempt to do so by employing one scalar field has failed due to the appearance of harmful singularities near the bounce. In this work, I use four scalar fields to construct a class of geometric sigma models which are free of singularities. The models within the class are parametrized by their background geometries. I prove that, whatever background is chosen, the dynamics of its small perturbations is classically stable on the whole time axis. Contrary to what one expects from the structure of the initial Lagrangian, the physics of background fluctuations is found to carry two tensor, two vector, and two scalar degrees of freedom. The graviton mass, which naturally appears in these models, is shown to be several orders of magnitude smaller than its experimental bound. I provide three simple examples to demonstrate how this is done in practice. In particular, I show that graviton mass can be made arbitrarily small.

  4. 22 CFR 51.26 - Photographs.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Photographs. 51.26 Section 51.26 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS Application § 51.26 Photographs. The applicant must submit with his or her application photographs as prescribed by the Department that are a...

  5. 22 CFR 62.26 - Specialists.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Specialists. 62.26 Section 62.26 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES EXCHANGE VISITOR PROGRAM Specific Program... such areas, for example, as mass media communication, environmental science, youth leadership...

  6. A Class of Manifold Regularized Multiplicative Update Algorithms for Image Clustering.

    Science.gov (United States)

    Yang, Shangming; Yi, Zhang; He, Xiaofei; Li, Xuelong

    2015-12-01

    Multiplicative update algorithms are important tools for information retrieval, image processing, and pattern recognition. However, when the graph regularization is added to the cost function, different classes of sample data may be mapped to the same subspace, which leads to the increase of data clustering error rate. In this paper, an improved nonnegative matrix factorization (NMF) cost function is introduced. Based on the cost function, a class of novel graph regularized NMF algorithms is developed, which results in a class of extended multiplicative update algorithms with manifold structure regularization. Analysis shows that in the learning, the proposed algorithms can efficiently minimize the rank of the data representation matrix. Theoretical results presented in this paper are confirmed by simulations. For different initializations and data sets, variation curves of cost functions and decomposition data are presented to show the convergence features of the proposed update rules. Basis images, reconstructed images, and clustering results are utilized to present the efficiency of the new algorithms. Last, the clustering accuracies of different algorithms are also investigated, which shows that the proposed algorithms can achieve state-of-the-art performance in applications of image clustering.

  7. Crystallogenesis of bacteriophage P22 tail accessory factor gp26 at acidic and neutral pH

    Energy Technology Data Exchange (ETDEWEB)

    Cingolani, Gino, E-mail: cingolag@upstate.edu; Andrews, Dewan [Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210 (United States); Casjens, Sherwood [Department of Pathology, Division of Cell Biology and Immunology, University of Utah Medical School, Salt Lake City, UT 84112 (United States); Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210 (United States)

    2006-05-01

    The crystallogenesis of bacteriophage P22 tail-fiber gp26 is described. To study possible pH-induced conformational changes in gp26 structure, native trimeric gp26 has been crystallized at acidic pH (4.6) and a chimera of gp26 fused to maltose-binding protein (MBP-gp26) has been crystallized at neutral and alkaline pH (7-10). Gp26 is one of three phage P22-encoded tail accessory factors essential for stabilization of viral DNA within the mature capsid. In solution, gp26 exists as an extended triple-stranded coiled-coil protein which shares profound structural similarities with class I viral membrane-fusion protein. In the cryo-EM reconstruction of P22 tail extracted from mature virions, gp26 forms an ∼220 Å extended needle structure emanating from the neck of the tail, which is likely to be brought into contact with the cell’s outer membrane when the viral DNA-injection process is initiated. To shed light on the potential role of gp26 in cell-wall penetration and DNA injection, gp26 has been crystallized at acidic, neutral and alkaline pH. Crystals of native gp26 grown at pH 4.6 diffract X-rays to 2.0 Å resolution and belong to space group P2{sub 1}, with a dimer of trimeric gp26 molecules in the asymmetric unit. To study potential pH-induced conformational changes in the gp26 structure, a chimera of gp26 fused to maltose-binding protein (MBP-gp26) was generated. Hexagonal crystals of MBP-gp26 were obtained at neutral and alkaline pH using the high-throughput crystallization robot at the Hauptman–Woodward Medical Research Institute, Buffalo, NY, USA. These crystals diffract X-rays to beyond 2.0 Å resolution. Structural analysis of gp26 crystallized at acidic, neutral and alkaline pH is in progress.

  8. 48 CFR 22.1019 - Additional classes of service employees.

    Science.gov (United States)

    2010-10-01

    ... regarding the agreement or disagreement of the employees' representative or the employees themselves... service employees. 22.1019 Section 22.1019 Federal Acquisition Regulations System FEDERAL ACQUISITION... of 1965, as Amended 22.1019 Additional classes of service employees. (a) If the contracting officer...

  9. LL-regular grammars

    NARCIS (Netherlands)

    Nijholt, Antinus

    1980-01-01

    Culik II and Cogen introduced the class of LR-regular grammars, an extension of the LR(k) grammars. In this paper we consider an analogous extension of the LL(k) grammars called the LL-regular grammars. The relation of this class of grammars to other classes of grammars will be shown. Any LL-regular

  10. 22 CFR 40.9 - Classes of inadmissible aliens.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Classes of inadmissible aliens. 40.9 Section 40.9 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH NONIMMIGRANTS AND... inadmissible aliens. Subparts B through L describe classes of inadmissible aliens who are ineligible to receive...

  11. Accurate stereochemistry for two related 22,26-epiminocholestene derivatives

    International Nuclear Information System (INIS)

    Vega-Baez, José Luis; Sandoval-Ramírez, Jesús; Meza-Reyes, Socorro; Montiel-Smith, Sara; Gómez-Calvario, Victor; Bernès, Sylvain

    2008-01-01

    Regioselective opening of ring E of solasodine under various conditions afforded (25R)-22,26-epimino@@cholesta-5,22(N)-di@@ene-3β,16β-diyl diacetate (previously known as 3,16-diacetyl pseudosolasodine B), C 31 H 47 NO 4 , or (22S,25R)-16β-hydr@@oxy-22,26-epimino@@cholesta-5-en-3β-yl acetate (a derivative of the naturally occurring alkaloid oblonginine), C 29 H 47 NO 3 . In both cases, the reactions are carried out with retention of chirality at the C16, C20 and C25 stereogenic centers, which are found to be S, S and R, respectively. Although pseudosolasodine was synthesized 50 years ago, these accurate assignments clarify some controversial points about the actual stereochemistry for these alkaloids. This is of particular importance in the case of oblonginine, since this compound is currently under consideration for the treatment of aphasia arising from apoplexy; the present study defines a diastereoisomerically pure compound for pharmacological studies

  12. Identification of Aquifex aeolicus tRNA (m2(2G26) methyltransferase gene.

    Science.gov (United States)

    Takeda, Hiroshi; Hori, Hiroyuki; Endo, Yaeta

    2002-01-01

    The modifications of N2,N2-dimethylguanine (m2(2)G) are found in tRNAs and rRNAs from eukarya and archaea. In tRNAs, modification at position G26 is generated by tRNA (m2(2)G26) methyltransferase, which is encoded by the corresponding gene, trm1. This enzyme catalyzes the methyl-transfer from S-adenosyl-L-methionine to the semi-conserved residue, G26, via the intermediate modified base, m2G26. Recent genome sequencing project has been reported that the putative trm1 is encoded in the genome of Aquifex aeolicus, a hyper-thermophilic eubacterium as only one exception among eubacteria. In order to confirm whether this bacterial trm1 gene product is a real tRNA (m2(2)G26) methyltransferase or not, we expressed this protein by wheat germ in vitro cell-free translation system. Our biochemical analysis clearly showed that this gene product possessed tRNA (m2(2)G26) methyltransferase activity.

  13. Periodontal Disease, Regular Dental Care Use, and Incident Ischemic Stroke.

    Science.gov (United States)

    Sen, Souvik; Giamberardino, Lauren D; Moss, Kevin; Morelli, Thiago; Rosamond, Wayne D; Gottesman, Rebecca F; Beck, James; Offenbacher, Steven

    2018-02-01

    Periodontal disease is independently associated with cardiovascular disease. Identification of periodontal disease as a risk factor for incident ischemic stroke raises the possibility that regular dental care utilization may reduce the stroke risk. In the ARIC (Atherosclerosis Risk in Communities) study, pattern of dental visits were classified as regular or episodic dental care users. In the ancillary dental ARIC study, selected subjects from ARIC underwent fullmouth periodontal measurements collected at 6 sites per tooth and classified into 7 periodontal profile classes (PPCs). In the ARIC study 10 362 stroke-free participants, 584 participants had incident ischemic strokes over a 15-year period. In the dental ARIC study, 6736 dentate subjects were assessed for periodontal disease status using PPC with a total of 299 incident ischemic strokes over the 15-year period. The 7 levels of PPC showed a trend toward an increased stroke risk (χ 2 trend P periodontal disease). Periodontal disease was significantly associated with cardioembolic (hazard ratio, 2.6; 95% confidence interval, 1.2-5.6) and thrombotic (hazard ratio, 2.2; 95% confidence interval, 1.3-3.8) stroke subtypes. Regular dental care utilization was associated with lower adjusted stroke risk (hazard ratio, 0.77; 95% confidence interval, 0.63-0.94). We confirm an independent association between periodontal disease and incident stroke risk, particularly cardioembolic and thrombotic stroke subtype. Further, we report that regular dental care utilization may lower this risk for stroke. © 2018 American Heart Association, Inc.

  14. The Characteristics and Extent of Participation of Deaf and Hard-of-Hearing Students in Regular Classes in Australian Schools.

    Science.gov (United States)

    Power, Des; Hyde, Merv

    2002-01-01

    A national randomly selected survey of a sample of deaf and hard-of-hearing students included in regular classes from kindergarten to high school in Australian preschools and schools was conducted via a questionnaire to itinerant teachers working with such students. This article reports the analysis of a questionnaire that surveyed the demographic characteristics of such students and a set of characteristics of their behavior in their placement in terms of "participation" in aspects of regular class activities. These aspects were level of integration, academic participation, level of independence, and social participation. Data are reported and analyzed in terms of the above demographic and participatory characteristics of the students. We consider comparisons with comparable reports from the United States and Great Britain and discuss implications for deaf and hard-of-hearing students included in regular classes.

  15. Accurate stereochemistry for two related 22,26-epiminocholestene derivatives

    Energy Technology Data Exchange (ETDEWEB)

    Vega-Baez, José Luis; Sandoval-Ramírez, Jesús; Meza-Reyes, Socorro; Montiel-Smith, Sara; Gómez-Calvario, Victor [Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Ciudad Universitaria, San Manuel, 72000 Puebla, Pue. (Mexico); Bernès, Sylvain, E-mail: sylvain-bernes@hotmail.com [DEP Facultad de Ciencias Químicas, UANL, Guerrero y Progreso S/N, Col. Treviño, 64570 Monterrey, NL (Mexico); Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Ciudad Universitaria, San Manuel, 72000 Puebla, Pue. (Mexico)

    2008-04-01

    Regioselective opening of ring E of solasodine under various conditions afforded (25R)-22,26-epimino@@cholesta-5,22(N)-di@@ene-3β,16β-diyl diacetate (previously known as 3,16-diacetyl pseudosolasodine B), C{sub 31}H{sub 47}NO{sub 4}, or (22S,25R)-16β-hydr@@oxy-22,26-epimino@@cholesta-5-en-3β-yl acetate (a derivative of the naturally occurring alkaloid oblonginine), C{sub 29}H{sub 47}NO{sub 3}. In both cases, the reactions are carried out with retention of chirality at the C16, C20 and C25 stereogenic centers, which are found to be S, S and R, respectively. Although pseudosolasodine was synthesized 50 years ago, these accurate assignments clarify some controversial points about the actual stereochemistry for these alkaloids. This is of particular importance in the case of oblonginine, since this compound is currently under consideration for the treatment of aphasia arising from apoplexy; the present study defines a diastereoisomerically pure compound for pharmacological studies.

  16. Social dimensions of inclusion in education of 4th and 7th grade pupils in inclusive and regular classes: Outcomes from Austria.

    Science.gov (United States)

    Schwab, Susanne

    2015-01-01

    Positive peer relationships play a significant role in the development of students. They are beneficial for learning and psychological outcomes. This article draws upon an important distinction between the four main themes of social participation (friendships, interactions, peer acceptance and self-perception of social participation) and examines these aspects in inclusive and regular classes. Especially, differences in social participation of students with and without special educational needs (SEN) in inclusive classes and between students without SEN in inclusive and regular classes are examined. In this study, data from 1115 pupils in primary and secondary schools in Austria were analysed, of which 129 were diagnosed as having SEN. The results showed that in inclusive classes, students with SEN had lower scores on all four subthemes of social participation (friendships, interactions, peer acceptance and self-perception of social integration) than students without SEN. Regarding students without SEN, friendships and peer acceptance were significantly higher in inclusive classes than in regular classes. Differences were neither found for gender, nor between primary and secondary school students. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. 22 CFR 224.26 - Form, filing and service of papers.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Form, filing and service of papers. 224.26... CIVIL REMEDIES ACT § 224.26 Form, filing and service of papers. (a) Form. (1) Documents filed with the ALJ shall include an original and two copies. (2) Every pleading and paper filed in the proceeding...

  18. Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model

    Directory of Open Access Journals (Sweden)

    Mittelmann Hans D

    2010-01-01

    Full Text Available Abstract Background The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a distinct subset of peptides and the enormous number of possible peptide epitopes prevents their complete experimental characterization. Computational methods can utilize the limited experimental data to predict the binding affinities of peptides to class II MHC. Results We have developed the Regularized Thermodynamic Average, or RTA, method for predicting the affinities of peptides binding to class II MHC. RTA accounts for all possible peptide binding conformations using a thermodynamic average and includes a parameter constraint for regularization to improve accuracy on novel data. RTA was shown to achieve higher accuracy, as measured by AUC, than SMM-align on the same data for all 17 MHC allotypes examined. RTA also gave the highest accuracy on all but three allotypes when compared with results from 9 different prediction methods applied to the same data. In addition, the method correctly predicted the peptide binding register of 17 out of 18 peptide-MHC complexes. Finally, we found that suboptimal peptide binding registers, which are often ignored in other prediction methods, made significant contributions of at least 50% of the total binding energy for approximately 20% of the peptides. Conclusions The RTA method accurately predicts peptide binding affinities to class II MHC and accounts for multiple peptide binding registers while reducing overfitting through regularization. The method has potential applications in vaccine design and in understanding autoimmune disorders. A web server implementing the RTA prediction method is available at http://bordnerlab.org/RTA/.

  19. 22 CFR 35.26 - Form, filing and service of papers.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Form, filing and service of papers. 35.26... REMEDIES § 35.26 Form, filing and service of papers. (a) Form. (1) Documents filed with the ALJ shall include an original and two copies. (2) Every pleading and paper filed in the proceeding shall contain a...

  20. 22 CFR 521.26 - Form, filing and service of papers.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Form, filing and service of papers. 521.26... REMEDIES ACT § 521.26 Form, filing and service of papers. (a) Form. (1) Documents filed with the ALJ shall include an original and two copies. (2) Every pleading and paper filed in the proceeding shall contain a...

  1. Decays of 22Al and 26P: discovery of beta-delayed two-proton radioactivity

    International Nuclear Information System (INIS)

    Cable, M.D.

    1983-02-01

    A helium-jet system and the 24 Mg( 3 He,p4n) 22 Al and 28 Si( 3 He,p4n) 26 P reactions have been used to discover the only known odd-odd, T/sub Z/ = -2 nuclides, 22 Al(t/sub 1/2/ approx. 70ms) and 26 P(t/sub 1/2/ approx. 20 ms). Observations of beta-delayed protons from each isotope (laboratory energies 7.839 +- 0.015 MeV and 8.149 +- 0.021 MeV for 22 Al and 7.269 +- 0.015 MeV and 6.827 +- 0.050 MeV for 26 P) established the existence of these nuclides and provided a measurement of the mass excesses of the lowest T = 2 states in their beta decay daughters, 22 Mg and 26 Si (13.650 +- 0.015 MeV and 5.936 +- 0.015 MeV, respectively). Measurement of these masses confirmed that these T = 2 states were unbound to two-proton emission as had been predicted theoretically

  2. Regular Network Class Features Enhancement Using an Evolutionary Synthesis Algorithm

    Directory of Open Access Journals (Sweden)

    O. G. Monahov

    2014-01-01

    Full Text Available This paper investigates a solution of the optimization problem concerning the construction of diameter-optimal regular networks (graphs. Regular networks are of practical interest as the graph-theoretical models of reliable communication networks of parallel supercomputer systems, as a basis of the structure in a model of small world in optical and neural networks. It presents a new class of parametrically described regular networks - hypercirculant networks (graphs. An approach that uses evolutionary algorithms for the automatic generation of parametric descriptions of optimal hypercirculant networks is developed. Synthesis of optimal hypercirculant networks is based on the optimal circulant networks with smaller degree of nodes. To construct optimal hypercirculant networks is used a template of circulant network from the known optimal families of circulant networks with desired number of nodes and with smaller degree of nodes. Thus, a generating set of the circulant network is used as a generating subset of the hypercirculant network, and the missing generators are synthesized by means of the evolutionary algorithm, which is carrying out minimization of diameter (average diameter of networks. A comparative analysis of the structural characteristics of hypercirculant, toroidal, and circulant networks is conducted. The advantage hypercirculant networks under such structural characteristics, as diameter, average diameter, and the width of bisection, with comparable costs of the number of nodes and the number of connections is demonstrated. It should be noted the advantage of hypercirculant networks of dimension three over four higher-dimensional tori. Thus, the optimization of hypercirculant networks of dimension three is more efficient than the introduction of an additional dimension for the corresponding toroidal structures. The paper also notes the best structural parameters of hypercirculant networks in comparison with iBT-networks previously

  3. 27 CFR 4.22 - Blends, cellar treatment, alteration of class or type.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Blends, cellar treatment, alteration of class or type. 4.22 Section 4.22 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF WINE Standards of...

  4. 26 CFR 12.4 - Election of Class Life Asset Depreciation Range System (ADR).

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Election of Class Life Asset Depreciation Range... Election of Class Life Asset Depreciation Range System (ADR). (a) Elections filed before February 1, 1972... tax return in accordance with § 1.167(a)-11 of this chapter (relating to depreciation allowances using...

  5. Contrary interfacial exciton dissociation at metal/organic interface in regular and reverse configuration organic solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Bo; Wu, Zhenghui; Tam, Hoi Lam; Zhu, Furong, E-mail: frzhu@hkbu.edu.hk [Department of Physics, Institute of Advanced Materials, and Institute of Research and Continuing Education (Shenzhen), Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, NT (Hong Kong)

    2014-09-08

    An opposite interfacial exciton dissociation behavior at the metal (Al)/organic cathode interface in regular and inverted organic solar cells (OSCs) was analyzed using transient photocurrent measurements. It is found that Al/organic contact in regular OSCs, made with the blend layer of poly[[4,8-bis[(2-ethylhexyl)oxy]benzo[1,2-b:4,5-b′]dithiophene-2,6-diyl] -[3-fluoro-2-[(2-ethylhexyl)carbonyl]thieno[3,4-b]-thiophenediyl

  6. [School well-being of students with and without special educational needs--a comparison of students in inclusive and regular classes].

    Science.gov (United States)

    Schwab, Susanne; Rossmann, Peter; Tanzer, Norbert; Hagn, Joachim; Oitzinger, Sabrina; Thurner, Verena; Wimberger, Tanja

    2015-07-01

    The present study examines the academic well-being of students with and without special educational needs (SEN) in inclusive classes compared to students from regular classes in which no child with SEN is taught. In addition, the relationships between the school well-being and emotional problems, conduct problems, hyperactivity/inattention, peer relationship problems and prosocial behavior are analyzed. A total of 1115 students from the 4th and 7th grade (37 % 4th graders, 63 % 7th graders) participated in the survey, 126 of whom had been diagnosed as having SEN. The subscale Well-Being at School taken from the FEESS 3–4 (Rauer & Schuck, 2004) and the SDQ (Goodman, 1997) were used for measurement. Results indicate high reliabilities for the subscale Well-Being in School for students both with and without SEN for both grades 4 and 7. Furthermore, it could be shown that the variance explained for school well-being can be connected to elements on the students’ individual level as well as on the class-specific level. Significant predictors of school well-being were sex, behavioral difficulties and strengths as well as the school grade. The SEN status (no SEN vs. SEN) and the class setting (regular vs. inclusive class) did not influence the school well-being significantly.

  7. Regularized maximum correntropy machine

    KAUST Repository

    Wang, Jim Jing-Yan; Wang, Yunji; Jing, Bing-Yi; Gao, Xin

    2015-01-01

    In this paper we investigate the usage of regularized correntropy framework for learning of classifiers from noisy labels. The class label predictors learned by minimizing transitional loss functions are sensitive to the noisy and outlying labels of training samples, because the transitional loss functions are equally applied to all the samples. To solve this problem, we propose to learn the class label predictors by maximizing the correntropy between the predicted labels and the true labels of the training samples, under the regularized Maximum Correntropy Criteria (MCC) framework. Moreover, we regularize the predictor parameter to control the complexity of the predictor. The learning problem is formulated by an objective function considering the parameter regularization and MCC simultaneously. By optimizing the objective function alternately, we develop a novel predictor learning algorithm. The experiments on two challenging pattern classification tasks show that it significantly outperforms the machines with transitional loss functions.

  8. Regularized maximum correntropy machine

    KAUST Repository

    Wang, Jim Jing-Yan

    2015-02-12

    In this paper we investigate the usage of regularized correntropy framework for learning of classifiers from noisy labels. The class label predictors learned by minimizing transitional loss functions are sensitive to the noisy and outlying labels of training samples, because the transitional loss functions are equally applied to all the samples. To solve this problem, we propose to learn the class label predictors by maximizing the correntropy between the predicted labels and the true labels of the training samples, under the regularized Maximum Correntropy Criteria (MCC) framework. Moreover, we regularize the predictor parameter to control the complexity of the predictor. The learning problem is formulated by an objective function considering the parameter regularization and MCC simultaneously. By optimizing the objective function alternately, we develop a novel predictor learning algorithm. The experiments on two challenging pattern classification tasks show that it significantly outperforms the machines with transitional loss functions.

  9. Reappraisal of the taxonomy of Streptococcus suis serotypes 20, 22 and 26: Streptococcus parasuis sp. nov.

    Science.gov (United States)

    Nomoto, R; Maruyama, F; Ishida, S; Tohya, M; Sekizaki, T; Osawa, Ro

    2015-02-01

    In order to clarify the taxonomic position of serotypes 20, 22 and 26 of Streptococcus suis, biochemical and molecular genetic studies were performed on isolates (SUT-7, SUT-286(T), SUT-319, SUT-328 and SUT-380) reacted with specific antisera of serotypes 20, 22 or 26 from the saliva of healthy pigs as well as reference strains of serotypes 20, 22 and 26. Comparative recN gene sequencing showed high genetic relatedness among our isolates, but marked differences from the type strain S. suis NCTC 10234(T), i.e. 74.8-75.7 % sequence similarity. The genomic relatedness between the isolates and other strains of species of the genus Streptococcus, including S. suis, was calculated using the average nucleotide identity values of whole genome sequences, which indicated that serotypes 20, 22 and 26 should be removed taxonomically from S. suis and treated as a novel genomic species. Comparative sequence analysis revealed 99.0-100 % sequence similarities for the 16S rRNA genes between the reference strains of serotypes 20, 22 and 26, and our isolates. Isolate STU-286(T) had relatively high 16S rRNA gene sequence similarity with S. suis NCTC 10234(T) (98.8 %). SUT-286(T) could be distinguished from S. suis and other closely related species of the genus Streptococcus using biochemical tests. Due to its phylogenetic and phenotypic similarities to S. suis we propose naming the novel species Streptococcus parasuis sp. nov., with SUT-286(T) ( = JCM 30273(T) = DSM 29126(T)) as the type strain. © 2015 IUMS.

  10. Conjugacy classes in the Weyl group admitting a regular eigenvector and integrable hierarchies

    International Nuclear Information System (INIS)

    Delduc, F.; Feher, L.

    1994-10-01

    The classification of the integrable hierarchies in the Drinfeld-Sokolov (DS) approach is studied. The DS construction, originally based on the principal Heisenberg subalgebra of an affine Lie algebra, has been recently generalized to arbitrary graded Heisenberg subalgebras. The graded Heisenberg subalgebras of an untwisted loop algebra l(G) are classified by the conjugacy classes in the Weyl group of G, but a complete classification of the hierarchies obtained from generalized DS reductions is still missing. The main result presented here is the complete list of the graded regular elements of l(G) for G a classical Lie algebra or G 2 , extending previous results on the gl n case. (author). 9 refs., 4 tabs

  11. Regular algebra and finite machines

    CERN Document Server

    Conway, John Horton

    2012-01-01

    World-famous mathematician John H. Conway based this classic text on a 1966 course he taught at Cambridge University. Geared toward graduate students of mathematics, it will also prove a valuable guide to researchers and professional mathematicians.His topics cover Moore's theory of experiments, Kleene's theory of regular events and expressions, Kleene algebras, the differential calculus of events, factors and the factor matrix, and the theory of operators. Additional subjects include event classes and operator classes, some regulator algebras, context-free languages, communicative regular alg

  12. Regularization of Nonmonotone Variational Inequalities

    International Nuclear Information System (INIS)

    Konnov, Igor V.; Ali, M.S.S.; Mazurkevich, E.O.

    2006-01-01

    In this paper we extend the Tikhonov-Browder regularization scheme from monotone to rather a general class of nonmonotone multivalued variational inequalities. We show that their convergence conditions hold for some classes of perfectly and nonperfectly competitive economic equilibrium problems

  13. 26 CFR 1.61-22 - Taxation of split-dollar life insurance arrangements.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Taxation of split-dollar life insurance..., and Taxable Income § 1.61-22 Taxation of split-dollar life insurance arrangements. (a) Scope—(1) In general. This section provides rules for the taxation of a split-dollar life insurance arrangement for...

  14. 40 CFR 264.259 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Science.gov (United States)

    2010-07-01

    ... HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Waste Piles § 264.259 Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27. (a) Hazardous Wastes FO20, FO21, FO22, FO23, FO26... requirements are necessary for piles managing hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27 in order...

  15. Maximum mutual information regularized classification

    KAUST Repository

    Wang, Jim Jing-Yan

    2014-09-07

    In this paper, a novel pattern classification approach is proposed by regularizing the classifier learning to maximize mutual information between the classification response and the true class label. We argue that, with the learned classifier, the uncertainty of the true class label of a data sample should be reduced by knowing its classification response as much as possible. The reduced uncertainty is measured by the mutual information between the classification response and the true class label. To this end, when learning a linear classifier, we propose to maximize the mutual information between classification responses and true class labels of training samples, besides minimizing the classification error and reducing the classifier complexity. An objective function is constructed by modeling mutual information with entropy estimation, and it is optimized by a gradient descend method in an iterative algorithm. Experiments on two real world pattern classification problems show the significant improvements achieved by maximum mutual information regularization.

  16. Maximum mutual information regularized classification

    KAUST Repository

    Wang, Jim Jing-Yan; Wang, Yi; Zhao, Shiguang; Gao, Xin

    2014-01-01

    In this paper, a novel pattern classification approach is proposed by regularizing the classifier learning to maximize mutual information between the classification response and the true class label. We argue that, with the learned classifier, the uncertainty of the true class label of a data sample should be reduced by knowing its classification response as much as possible. The reduced uncertainty is measured by the mutual information between the classification response and the true class label. To this end, when learning a linear classifier, we propose to maximize the mutual information between classification responses and true class labels of training samples, besides minimizing the classification error and reducing the classifier complexity. An objective function is constructed by modeling mutual information with entropy estimation, and it is optimized by a gradient descend method in an iterative algorithm. Experiments on two real world pattern classification problems show the significant improvements achieved by maximum mutual information regularization.

  17. 26 CFR 1.162-22 - Treble damage payments under the antitrust laws.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Treble damage payments under the antitrust laws... Corporations § 1.162-22 Treble damage payments under the antitrust laws. (a) In general. In the case of a... Federal antitrust laws or enters a plea of guilty or nolo contendere to an indictment or information...

  18. Inclusion Professional Development Model and Regular Middle School Educators

    Science.gov (United States)

    Royster, Otelia; Reglin, Gary L.; Losike-Sedimo, Nonofo

    2014-01-01

    The purpose of this study was to determine the impact of a professional development model on regular education middle school teachers' knowledge of best practices for teaching inclusive classes and attitudes toward teaching these classes. There were 19 regular education teachers who taught the core subjects. Findings for Research Question 1…

  19. Regular and context-free nominal traces

    DEFF Research Database (Denmark)

    Degano, Pierpaolo; Ferrari, Gian-Luigi; Mezzetti, Gianluca

    2017-01-01

    Two kinds of automata are presented, for recognising new classes of regular and context-free nominal languages. We compare their expressive power with analogous proposals in the literature, showing that they express novel classes of languages. Although many properties of classical languages hold ...

  20. 40 CFR 264.231 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Science.gov (United States)

    2010-07-01

    ... HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Surface Impoundments § 264.231 Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27. (a) Hazardous Wastes FO20, FO21, FO22... surface impoundments managing hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27 in order to reduce...

  1. A projection-based approach to general-form Tikhonov regularization

    DEFF Research Database (Denmark)

    Kilmer, Misha E.; Hansen, Per Christian; Espanol, Malena I.

    2007-01-01

    We present a projection-based iterative algorithm for computing general-form Tikhonov regularized solutions to the problem minx| Ax-b |2^2+lambda2| Lx |2^2, where the regularization matrix L is not the identity. Our algorithm is designed for the common case where lambda is not known a priori...

  2. New regular black hole solutions

    International Nuclear Information System (INIS)

    Lemos, Jose P. S.; Zanchin, Vilson T.

    2011-01-01

    In the present work we consider general relativity coupled to Maxwell's electromagnetism and charged matter. Under the assumption of spherical symmetry, there is a particular class of solutions that correspond to regular charged black holes whose interior region is de Sitter, the exterior region is Reissner-Nordstroem and there is a charged thin-layer in-between the two. The main physical and geometrical properties of such charged regular black holes are analyzed.

  3. 26 CFR 1.167(a)-12 - Depreciation based on class lives for property first placed in service before January 1, 1971.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Depreciation based on class lives for property... (CONTINUED) Itemized Deductions for Individuals and Corporations § 1.167(a)-12 Depreciation based on class... section provides an elective class life system for determining the reasonable allowance for depreciation...

  4. Liquid-liquid extraction of Th4+ and UO22+ by LIX-26 and its mixtures

    International Nuclear Information System (INIS)

    Singh, S.; Panda, C.R.; Chakravortty, V.; Dash, K.C.

    1988-01-01

    Solvent extractions of thorium(IV) and uranium(VI) by a commercially available chelating extractant LIX-26 (an alkylated 8-hydroxyquinoline) of 8-hydroxyquinoline, benzoic or salicylic acid, dipentyl sulfoxide (DPSO) and their mixtures with butanol as modifier in benzene/methylisobutyl ketone (MIBK) as a diluent were studied. The influence of concentration of various anions on the extraction of Th 4+ by mixtures of LIX-26 and benzoic acid was studied. Studies on extraction of thorium(IV) and uranium(VI) by mixtures of LIX-26 (HQ) and DPSO show that the extracted species are possibly of the type [(ThQ 2 (DPSO) 2 (SCN) 2 )] and [(UO 2 Q 2 (DPSO)]), respectively. (author) 22 refs.; 8 figs

  5. Geometric regularizations and dual conifold transitions

    International Nuclear Information System (INIS)

    Landsteiner, Karl; Lazaroiu, Calin I.

    2003-01-01

    We consider a geometric regularization for the class of conifold transitions relating D-brane systems on noncompact Calabi-Yau spaces to certain flux backgrounds. This regularization respects the SL(2,Z) invariance of the flux superpotential, and allows for computation of the relevant periods through the method of Picard-Fuchs equations. The regularized geometry is a noncompact Calabi-Yau which can be viewed as a monodromic fibration, with the nontrivial monodromy being induced by the regulator. It reduces to the original, non-monodromic background when the regulator is removed. Using this regularization, we discuss the simple case of the local conifold, and show how the relevant field-theoretic information can be extracted in this approach. (author)

  6. Forcing absoluteness and regularity properties

    NARCIS (Netherlands)

    Ikegami, D.

    2010-01-01

    For a large natural class of forcing notions, we prove general equivalence theorems between forcing absoluteness statements, regularity properties, and transcendence properties over L and the core model K. We use our results to answer open questions from set theory of the reals.

  7. Genealogies and spiritualities in Genesis 4:17-22, 4:25-26, 5:1-32 ...

    African Journals Online (AJOL)

    The three genealogies in Genesis 4:17-22, 4:25-26 en 5:1-32 show different intentions: the first wants (amongst other purposes) to give an aetiology of the trades; the second wants to stress the importance of a new beginning; the third wants to relate Adam to Noah. Each of these approaches to genealogy has a different ...

  8. Complexity in union-free regular languages

    Czech Academy of Sciences Publication Activity Database

    Jirásková, G.; Masopust, Tomáš

    2011-01-01

    Roč. 22, č. 7 (2011), s. 1639-1653 ISSN 0129-0541 Institutional research plan: CEZ:AV0Z10190503 Keywords : Union-free regular language * one-cycle-free-path automaton * descriptional complexity Subject RIV: BA - General Mathematics Impact factor: 0.379, year: 2011 http://www.worldscinet.com/ijfcs/22/2207/S0129054111008933.html

  9. Complexity in union-free regular languages

    Czech Academy of Sciences Publication Activity Database

    Jirásková, G.; Masopust, Tomáš

    2011-01-01

    Roč. 22, č. 7 (2011), s. 1639-1653 ISSN 0129-0541 Institutional research plan: CEZ:AV0Z10190503 Keywords : Union-free regular language * one-cycle-free- path automaton * descriptional complexity Subject RIV: BA - General Mathematics Impact factor: 0.379, year: 2011 http://www.worldscinet.com/ijfcs/22/2207/S0129054111008933.html

  10. Re-examining the 26Mg(α ,α')26Mg reaction: Probing astrophysically important states in 26Mg

    Science.gov (United States)

    Adsley, P.; Brümmer, J. W.; Li, K. C. W.; Marín-Lámbarri, D. J.; Kheswa, N. Y.; Donaldson, L. M.; Neveling, R.; Papka, P.; Pellegri, L.; Pesudo, V.; Pool, L. C.; Smit, F. D.; van Zyl, J. J.

    2017-11-01

    Background: The 22Ne(α ,n )25Mg reaction is one of the neutron sources for the s process in massive stars. The properties of levels in 26Mg above the α -particle threshold control the strengths of the 22Ne(α ,n )25Mg and 22Ne(α ,γ )26Mg reactions. The strengths of these reactions as functions of temperature are one of the major uncertainties in the s process. Purpose: Information on the existence, spin, and parity of levels in 26Mg can assist in constraining the strengths of the 22Ne(α ,γ )26Mg and 22Ne(α ,n )25Mg reactions, and therefore in constraining s -process abundances. Methods: Inelastically scattered α particles from a 26Mg target were momentum-analyzed in the K600 magnetic spectrometer at iThemba LABS, South Africa. The differential cross sections of states were deduced from the focal-plane trajectory of the scattered α particles. Based on the differential cross sections, spin and parity assignments to states are made. Results: A newly assigned 0+ state was observed in addition to a number of other states, some of which can be associated with states observed in other experiments. Some of the deduced Jπ values of the states observed in the present study show discrepancies with those assigned in a similar experiment performed at RCNP Osaka. The reassignments and additions of the various states can strongly affect the reaction rate at low temperatures. Conclusion: The number, location, and assignment of levels in 26Mg that may contribute to the 22Ne+α reactions are not clear. Future experimental investigations of 26Mg must have an extremely good energy resolution to separate the contributions from different levels. Coincidence experiments of 26Mg provide a possible route for future investigations.

  11. A new method for the regularization of a class of divergent Feynman integrals in covariant and axial gauges

    International Nuclear Information System (INIS)

    Lee, H.C.; Milgram, M.S.

    1984-07-01

    A hybrid of dimensional and analytic regularization is used to regulate and uncover a Meijer's G-function representation for a class of massless, divergent Feynman integrals in an axial gauge. Integrals in the covariant gauge belong to a subclass and those in the light-cone gauge are reached by analytic continuation. The method decouples the physical ultraviolet and infrared singularities from the spurious axial gauge singularity but regulates all three simultaneously. For the axial gauge singularity, the new analytic method is more powerful and elegant than the old principal value prescription, but the two methods yield identical infinite as well as regular parts. It is shown that dimensional and analytic regularization can be made equivalent, implying that the former method is free from spurious γ5-anomalies and the latter preserves gauge invariance. The hybrid method permits the evaluation of integrals containing arbritrary integer powers of logarithms in the integrand by differentiation with respect to exponents. Such 'exponent derivatives' generate the same set of 'polylogs' as that generated in multi-loop integrals in perturbation theories and may be useful for solving equations in nonperturbation theories. The close relation between the method of exponent derivatives and the prescription of 't Hooft and Veltman for treating overlapping divergencies is pointed out. It is demonstrated that both methods generate functions that are free from unrecognizable logarithmic infinite parts. Nonperturbation theories expressed in terms of exponent derivatives are thus renormalizable. Some intriguing connections between nonperturbation theories and nonintegral exponents are pointed out

  12. WATER TEMPERATURE and other data from UNKNOWN from 1989-01-26 to 1990-02-22 (NCEI Accession 9000062)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains physical profile water depth and temperature data. The bathythermograph (XBT) data was collected between January 26, 1990 and February 22,...

  13. 49 CFR 173.115 - Class 2, Divisions 2.1, 2.2, and 2.3-Definitions.

    Science.gov (United States)

    2010-10-01

    ... substances of Class 8, PG I are forbidden from transportation in an aerosol container. (7) Flammable... 2.1, 2.2, and 2.3—Definitions. (a) Division 2.1 (Flammable gas). For the purpose of this subchapter, a flammable gas (Division 2.1) means any material which is a gas at 20 °C (68 °F) or less and 101.3...

  14. NREL Pyrheliometer Comparisons: September 22-26, 2014 (NPC-2014)

    Energy Technology Data Exchange (ETDEWEB)

    Reda, I.; Dooraghi, M.; Habte, A.

    2014-10-01

    Accurate measurements of direct normal (beam) solar irradiance from pyrheliometers are important for developing and deploying solar energy conversion systems, improving our understanding of the Earth's energy budget for climate change studies, and for other science and technology applications involving solar flux. Providing these measurements places many demands on the quality system used by the operator of commercially available radiometers. Maintaining accurate radiometer calibrations that are traceable to an international standard is the first step in producing research-quality solar irradiance measurements. As with all measurement systems, absolute cavity radiometers and other types of pyrheliometers are subject to performance changes over time. NREL has developed and maintained a select group of absolute cavity radiometers with direct calibration traceability to the World Radiometric Reference (WRR), and uses these reference instruments to calibrate pyrheliometers and pyranometers using the ISO 17025 accredited Broadband Outdoor Radiometer Calibration (BORCAL) process. National Renewable Energy Laboratory (NREL) pyrheliometer comparisons (NPCs) are held annually at the Solar Radiation Research Laboratory (SRRL) in Golden, Colorado. Open to all pyrheliometer owners and operators, each NPC provides an opportunity to determine the unique WRR transfer factor (WRR-TF) for each participating pyrheliometer. By adjusting all subsequent pyrheliometer measurements by the appropriate WRR-TF, the solar irradiance data are traceable to the WRR. NPC-2014 was held September 22-26, 2014. Participants operated 36 absolute cavity radiometers and 22 conventional thermopile-based pyrheliometers to simultaneously measure clear-sky direct normal solar irradiance during this period, and this report documents the findings.

  15. Globals of Completely Regular Monoids

    Institute of Scientific and Technical Information of China (English)

    Wu Qian-qian; Gan Ai-ping; Du Xian-kun

    2015-01-01

    An element of a semigroup S is called irreducible if it cannot be expressed as a product of two elements in S both distinct from itself. In this paper we show that the class C of all completely regular monoids with irreducible identity elements satisfies the strong isomorphism property and so it is globally determined.

  16. Ensino de ciências para deficientes auditivos: um estudo sobre a produção de narrativas em classes regulares inclusivas

    Directory of Open Access Journals (Sweden)

    Walquíria D. de Oliveira

    2012-07-01

    Full Text Available The education of deaf people in regular schools is a challenge because for a long time not given due importance to their way of communication, sign language. With the inclusion of the deaf students have been put into the regular school and there is a need for a new agent on vital for their integration, the interpreter of Brazilian sign language (libras. The aim ofthis study is to analyze the narratives production by libras interpreters and science teachers in the inclusive classroom. The investigation of this issue brings the discussion questions as: what is the role of the educational interpreter? What is prescribed and what is real in the process of inclusion? The methodological approach adopted is based on Zabalza that uses the class diaries as research instruments, where the subject is searched without being noticed. The results point to a lack of knowledge of language constituted the main dilemma in the education of the deaf. Keywords: inclusive education, science education, deafness

  17. Regularized Discriminant Analysis: A Large Dimensional Study

    KAUST Repository

    Yang, Xiaoke

    2018-04-28

    In this thesis, we focus on studying the performance of general regularized discriminant analysis (RDA) classifiers. The data used for analysis is assumed to follow Gaussian mixture model with different means and covariances. RDA offers a rich class of regularization options, covering as special cases the regularized linear discriminant analysis (RLDA) and the regularized quadratic discriminant analysis (RQDA) classi ers. We analyze RDA under the double asymptotic regime where the data dimension and the training size both increase in a proportional way. This double asymptotic regime allows for application of fundamental results from random matrix theory. Under the double asymptotic regime and some mild assumptions, we show that the asymptotic classification error converges to a deterministic quantity that only depends on the data statistical parameters and dimensions. This result not only implicates some mathematical relations between the misclassification error and the class statistics, but also can be leveraged to select the optimal parameters that minimize the classification error, thus yielding the optimal classifier. Validation results on the synthetic data show a good accuracy of our theoretical findings. We also construct a general consistent estimator to approximate the true classification error in consideration of the unknown previous statistics. We benchmark the performance of our proposed consistent estimator against classical estimator on synthetic data. The observations demonstrate that the general estimator outperforms others in terms of mean squared error (MSE).

  18. Regularized Label Relaxation Linear Regression.

    Science.gov (United States)

    Fang, Xiaozhao; Xu, Yong; Li, Xuelong; Lai, Zhihui; Wong, Wai Keung; Fang, Bingwu

    2018-04-01

    Linear regression (LR) and some of its variants have been widely used for classification problems. Most of these methods assume that during the learning phase, the training samples can be exactly transformed into a strict binary label matrix, which has too little freedom to fit the labels adequately. To address this problem, in this paper, we propose a novel regularized label relaxation LR method, which has the following notable characteristics. First, the proposed method relaxes the strict binary label matrix into a slack variable matrix by introducing a nonnegative label relaxation matrix into LR, which provides more freedom to fit the labels and simultaneously enlarges the margins between different classes as much as possible. Second, the proposed method constructs the class compactness graph based on manifold learning and uses it as the regularization item to avoid the problem of overfitting. The class compactness graph is used to ensure that the samples sharing the same labels can be kept close after they are transformed. Two different algorithms, which are, respectively, based on -norm and -norm loss functions are devised. These two algorithms have compact closed-form solutions in each iteration so that they are easily implemented. Extensive experiments show that these two algorithms outperform the state-of-the-art algorithms in terms of the classification accuracy and running time.

  19. Annotation of regular polysemy and underspecification

    DEFF Research Database (Denmark)

    Martínez Alonso, Héctor; Pedersen, Bolette Sandford; Bel, Núria

    2013-01-01

    We present the result of an annotation task on regular polysemy for a series of seman- tic classes or dot types in English, Dan- ish and Spanish. This article describes the annotation process, the results in terms of inter-encoder agreement, and the sense distributions obtained with two methods...

  20. Gl(2/2)-oscillators and Gl(2/2)-dynamical symmetry

    International Nuclear Information System (INIS)

    Kamupingene, A.H.; Nguyen Anh Ky.

    1991-07-01

    Extending the concept of the dynamical symmetry, we identify the Lie superalgebra Gl(2/2) as a dynamical (super-)algebra of a class of non-canonical quantum systems, whose dynamical variables and quantities can be realized in terms of the Gl(2/2)-generators. In this way, a new class of harmonic oscillators is established. As a consequence of the choice of the dynamical variables the Heisenberg algebra and the Hermitian condition for the Gl(2/2)-representations are also given. (author). 12 refs

  1. Asymptotic performance of regularized quadratic discriminant analysis based classifiers

    KAUST Repository

    Elkhalil, Khalil

    2017-12-13

    This paper carries out a large dimensional analysis of the standard regularized quadratic discriminant analysis (QDA) classifier designed on the assumption that data arise from a Gaussian mixture model. The analysis relies on fundamental results from random matrix theory (RMT) when both the number of features and the cardinality of the training data within each class grow large at the same pace. Under some mild assumptions, we show that the asymptotic classification error converges to a deterministic quantity that depends only on the covariances and means associated with each class as well as the problem dimensions. Such a result permits a better understanding of the performance of regularized QDA and can be used to determine the optimal regularization parameter that minimizes the misclassification error probability. Despite being valid only for Gaussian data, our theoretical findings are shown to yield a high accuracy in predicting the performances achieved with real data sets drawn from popular real data bases, thereby making an interesting connection between theory and practice.

  2. Manifold regularized multitask learning for semi-supervised multilabel image classification.

    Science.gov (United States)

    Luo, Yong; Tao, Dacheng; Geng, Bo; Xu, Chao; Maybank, Stephen J

    2013-02-01

    It is a significant challenge to classify images with multiple labels by using only a small number of labeled samples. One option is to learn a binary classifier for each label and use manifold regularization to improve the classification performance by exploring the underlying geometric structure of the data distribution. However, such an approach does not perform well in practice when images from multiple concepts are represented by high-dimensional visual features. Thus, manifold regularization is insufficient to control the model complexity. In this paper, we propose a manifold regularized multitask learning (MRMTL) algorithm. MRMTL learns a discriminative subspace shared by multiple classification tasks by exploiting the common structure of these tasks. It effectively controls the model complexity because different tasks limit one another's search volume, and the manifold regularization ensures that the functions in the shared hypothesis space are smooth along the data manifold. We conduct extensive experiments, on the PASCAL VOC'07 dataset with 20 classes and the MIR dataset with 38 classes, by comparing MRMTL with popular image classification algorithms. The results suggest that MRMTL is effective for image classification.

  3. Regular Gleason Measures and Generalized Effect Algebras

    Science.gov (United States)

    Dvurečenskij, Anatolij; Janda, Jiří

    2015-12-01

    We study measures, finitely additive measures, regular measures, and σ-additive measures that can attain even infinite values on the quantum logic of a Hilbert space. We show when particular classes of non-negative measures can be studied in the frame of generalized effect algebras.

  4. Learning regularization parameters for general-form Tikhonov

    International Nuclear Information System (INIS)

    Chung, Julianne; Español, Malena I

    2017-01-01

    Computing regularization parameters for general-form Tikhonov regularization can be an expensive and difficult task, especially if multiple parameters or many solutions need to be computed in real time. In this work, we assume training data is available and describe an efficient learning approach for computing regularization parameters that can be used for a large set of problems. We consider an empirical Bayes risk minimization framework for finding regularization parameters that minimize average errors for the training data. We first extend methods from Chung et al (2011 SIAM J. Sci. Comput. 33 3132–52) to the general-form Tikhonov problem. Then we develop a learning approach for multi-parameter Tikhonov problems, for the case where all involved matrices are simultaneously diagonalizable. For problems where this is not the case, we describe an approach to compute near-optimal regularization parameters by using operator approximations for the original problem. Finally, we propose a new class of regularizing filters, where solutions correspond to multi-parameter Tikhonov solutions, that requires less data than previously proposed optimal error filters, avoids the generalized SVD, and allows flexibility and novelty in the choice of regularization matrices. Numerical results for 1D and 2D examples using different norms on the errors show the effectiveness of our methods. (paper)

  5. Human Diversity : Design for life: 9th International Congress of Physiological Anthropology: Proceedings, Delft, The Netherlands, 22-26 August 2008

    NARCIS (Netherlands)

    Louts, T.; Reitenbach, M.E.F.R.; Molenbroek, J.F.M.

    2009-01-01

    This book of full papers contains the proceedings of the ICPA (International Congress of Physiological Anthropology) conference, held at the faculty of Industrial Design Engineering, TU Delft, from 22-26 August 2008.

  6. Variations and Regularities in the Hemispheric Distributions in Sunspot Groups of Various Classes

    Science.gov (United States)

    Gao, Peng-Xin

    2018-05-01

    The present study investigates the variations and regularities in the distributions in sunspot groups (SGs) of various classes in the northern and southern hemispheres from Solar Cycles (SCs) 12 to 23. Here, we use the separation scheme that was introduced by Gao, Li, and Li ( Solar Phys. 292, 124, 2017), which is based on A/U ( A is the corrected area of the SG, and U is the corrected umbral area of the SG), in order to separate SGs into simple SGs (A/U ≤ 4.5) and complex SGs (A/U > 6.2). The time series of Greenwich photoheliographic results from 1875 to 1976 (corresponding to complete SCs 12 - 20) and Debrecen photoheliographic data during the period 1974 - 2015 (corresponding to complete SCs 21 - 23) are used to show the distributions of simple and complex SGs in the northern and southern hemispheres. The main results we obtain are reported as follows: i) the larger of the maximum annual simple SG numbers in the two hemispheres and the larger of the maximum annual complex SG numbers in the two hemispheres occur in different hemispheres during SCs 12, 14, 18, and 19; ii) the relative changing trends of two curves - cumulative SG numbers in the northern and southern hemispheres - for simple SGs are different from those for complex SGs during SCs 12, 14, 18, and 21; and iii) there are discrepancies between the dominant hemispheres of simple and complex SGs for SCs 12, 14, 18, and 21.

  7. Regularization of the Boundary-Saddle-Node Bifurcation

    Directory of Open Access Journals (Sweden)

    Xia Liu

    2018-01-01

    Full Text Available In this paper we treat a particular class of planar Filippov systems which consist of two smooth systems that are separated by a discontinuity boundary. In such systems one vector field undergoes a saddle-node bifurcation while the other vector field is transversal to the boundary. The boundary-saddle-node (BSN bifurcation occurs at a critical value when the saddle-node point is located on the discontinuity boundary. We derive a local topological normal form for the BSN bifurcation and study its local dynamics by applying the classical Filippov’s convex method and a novel regularization approach. In fact, by the regularization approach a given Filippov system is approximated by a piecewise-smooth continuous system. Moreover, the regularization process produces a singular perturbation problem where the original discontinuous set becomes a center manifold. Thus, the regularization enables us to make use of the established theories for continuous systems and slow-fast systems to study the local behavior around the BSN bifurcation.

  8. A New Class of Atomically Precise, Hydride-Rich Silver Nanoclusters Co-Protected by Phosphines

    KAUST Repository

    Bootharaju, Megalamane Siddaramappa

    2016-10-10

    Thiols and phosphines are the most widely used organic ligands to attain atomically precise metal nanoclusters (NCs). Here, we used simple hydrides (e.g., H–) as ligands along with phosphines, such as triphenylphosphine (TPP), 1,2-bis(diphenylphosphino)ethane [DPPE], and tris(4-fluorophenyl)phosphine [TFPP] to design and synthesize a new class of hydride-rich silver NCs. This class includes [Ag18H16(TPP)10]2+, [Ag25H22(DPPE)8]3+, and [Ag26H22(TFPP)13]2+. Our work reveals a new family of atomically precise NCs protected by H– ligands and labile phosphines, with potentially more accessible active metal sites for functionalization and provides a new set of stable NC sizes with simpler ligand–metal bonding for researchers to explore both experimentally and computationally.

  9. A Large Dimensional Analysis of Regularized Discriminant Analysis Classifiers

    KAUST Repository

    Elkhalil, Khalil

    2017-11-01

    This article carries out a large dimensional analysis of standard regularized discriminant analysis classifiers designed on the assumption that data arise from a Gaussian mixture model with different means and covariances. The analysis relies on fundamental results from random matrix theory (RMT) when both the number of features and the cardinality of the training data within each class grow large at the same pace. Under mild assumptions, we show that the asymptotic classification error approaches a deterministic quantity that depends only on the means and covariances associated with each class as well as the problem dimensions. Such a result permits a better understanding of the performance of regularized discriminant analsysis, in practical large but finite dimensions, and can be used to determine and pre-estimate the optimal regularization parameter that minimizes the misclassification error probability. Despite being theoretically valid only for Gaussian data, our findings are shown to yield a high accuracy in predicting the performances achieved with real data sets drawn from the popular USPS data base, thereby making an interesting connection between theory and practice.

  10. Viscous Regularization of the Euler Equations and Entropy Principles

    KAUST Repository

    Guermond, Jean-Luc

    2014-03-11

    This paper investigates a general class of viscous regularizations of the compressible Euler equations. A unique regularization is identified that is compatible with all the generalized entropies, à la [Harten et al., SIAM J. Numer. Anal., 35 (1998), pp. 2117-2127], and satisfies the minimum entropy principle. A connection with a recently proposed phenomenological model by [H. Brenner, Phys. A, 370 (2006), pp. 190-224] is made. © 2014 Society for Industrial and Applied Mathematics.

  11. Zero-One Law for Regular Languages and Semigroups with Zero

    OpenAIRE

    Sin'ya, Ryoma

    2015-01-01

    A regular language has the zero-one law if its asymptotic density converges to either zero or one. We prove that the class of all zero-one languages is closed under Boolean operations and quotients. Moreover, we prove that a regular language has the zero-one law if and only if its syntactic monoid has a zero element. Our proof gives both algebraic and automata characterisation of the zero-one law for regular languages, and it leads the following two corollaries: (i) There is an O(n log n) alg...

  12. [The impact of a 14- day regular physical exercise regime on the concentration of the classes and subclasses of lipoprotein particles in young subjects with a sedentary lifestyle].

    Science.gov (United States)

    Sabaka, P; Dukát, A; Oravec, S; Mistríková, L; Baláž, D; Bendžala, M; Gašpar, L

    2013-10-01

    Recommendations from the cardiological professional companies working in the area of primary prevention of cardiovascular diseases put an emphasis on regular aerobic physical activity. Its positive effect on both cardiovascular and overall mortality has repea-tedly been proven by the observations of prospective and cross sectional epidemiological studies. One of the possible explanations of this positive effect is a change in the concentration of lipoprotein classes and their subclasses, which is expressed as a change in their average size. In a group of young healthy men and women with a sedentary lifestyle we observed the effect of medium intensive physical exercise in the form of a 30- minute slow run per day lasting for 14 days. The concentration of lipoprotein classes and subclasses were determined through the method of a linear electrophoresis in polyacrylamide gel. In the observed group we found a statistically significant decrease of VLDL, large IDL particles, medium sized LDL, small dense LDL, and medium sized HDL particles. In the light of current knowledge all these lipoprotein particles are deemed as atherogenic. Thus, as little as 14 days of regular exercising has a positive effect on the concentration of plasmatic lipoproteins, and emphasises the role of regular physical activity in the primary prevention of cardiovascular diseases.

  13. Semiclassical Weyl Formula for a Class of Weakly Regular Elliptic Operators

    Energy Technology Data Exchange (ETDEWEB)

    Zielinski, Lech [Universite du Littoral, LMPA, Centre Mi-Voix (France)], E-mail: Lech.Zielinski@lmpa.univ-littoral.fr

    2006-02-15

    We investigate the semiclassical Weyl formula describing the asymptotic behaviour of the counting function for the number of eigenvalues in the case of self-adjoint elliptic differential operators satisfying weak regularity hypotheses. We consider symbols with possible critical points and with coefficients which have Hoelder continuous derivatives of first order.

  14. Semiclassical Weyl Formula for a Class of Weakly Regular Elliptic Operators

    International Nuclear Information System (INIS)

    Zielinski, Lech

    2006-01-01

    We investigate the semiclassical Weyl formula describing the asymptotic behaviour of the counting function for the number of eigenvalues in the case of self-adjoint elliptic differential operators satisfying weak regularity hypotheses. We consider symbols with possible critical points and with coefficients which have Hoelder continuous derivatives of first order

  15. Regularity of C*-algebras and central sequence algebras

    DEFF Research Database (Denmark)

    Christensen, Martin S.

    The main topic of this thesis is regularity properties of C*-algebras and how these regularity properties are re ected in their associated central sequence algebras. The thesis consists of an introduction followed by four papers [A], [B], [C], [D]. In [A], we show that for the class of simple...... Villadsen algebra of either the rst type with seed space a nite dimensional CW complex, or the second type, tensorial absorption of the Jiang-Su algebra is characterized by the absence of characters on the central sequence algebra. Additionally, in a joint appendix with Joan Bosa, we show that the Villadsen...... algebra of the second type with innite stable rank fails the corona factorization property. In [B], we consider the class of separable C*-algebras which do not admit characters on their central sequence algebra, and show that it has nice permanence properties. We also introduce a new divisibility property...

  16. Closedness type regularity conditions in convex optimization and beyond

    Directory of Open Access Journals (Sweden)

    Sorin-Mihai Grad

    2016-09-01

    Full Text Available The closedness type regularity conditions have proven during the last decade to be viable alternatives to their more restrictive interiority type counterparts, in both convex optimization and different areas where it was successfully applied. In this review article we de- and reconstruct some closedness type regularity conditions formulated by means of epigraphs and subdifferentials, respectively, for general optimization problems in order to stress that they arise naturally when dealing with such problems. The results are then specialized for constrained and unconstrained convex optimization problems. We also hint towards other classes of optimization problems where closedness type regularity conditions were successfully employed and discuss other possible applications of them.

  17. High frequency of the IVS2-2A>G DNA sequence variation in SLC26A5, encoding the cochlear motor protein prestin, precludes its involvement in hereditary hearing loss

    Directory of Open Access Journals (Sweden)

    Pereira Fred A

    2005-08-01

    Full Text Available Abstract Background Cochlear outer hair cells change their length in response to variations in membrane potential. This capability, called electromotility, is believed to enable the sensitivity and frequency selectivity of the mammalian cochlea. Prestin is a transmembrane protein required for electromotility. Homozygous prestin knockout mice are profoundly hearing impaired. In humans, a single nucleotide change in SLC26A5, encoding prestin, has been reported in association with hearing loss. This DNA sequence variation, IVS2-2A>G, occurs in the exon 3 splice acceptor site and is expected to abolish splicing of exon 3. Methods To further explore the relationship between hearing loss and the IVS2-2A>G transition, and assess allele frequency, genomic DNA from hearing impaired and control subjects was analyzed by DNA sequencing. SLC26A5 genomic DNA sequences from human, chimp, rat, mouse, zebrafish and fruit fly were aligned and compared for evolutionary conservation of the exon 3 splice acceptor site. Alternative splice acceptor sites within intron 2 of human SLC26A5 were sought using a splice site prediction program from the Berkeley Drosophila Genome Project. Results The IVS2-2A>G variant was found in a heterozygous state in 4 of 74 hearing impaired subjects of Hispanic, Caucasian or uncertain ethnicity and 4 of 150 Hispanic or Caucasian controls (p = 0.45. The IVS2-2A>G variant was not found in 106 subjects of Asian or African American descent. No homozygous subjects were identified (n = 330. Sequence alignment of SLC26A5 orthologs demonstrated that the A nucleotide at position IVS2-2 is invariant among several eukaryotic species. Sequence analysis also revealed five potential alternative splice acceptor sites in intron 2 of human SLC26A5. Conclusion These data suggest that the IVS2-2A>G variant may not occur more frequently in hearing impaired subjects than in controls. The identification of five potential alternative splice acceptor sites in

  18. UNFOLDED REGULAR AND SEMI-REGULAR POLYHEDRA

    Directory of Open Access Journals (Sweden)

    IONIŢĂ Elena

    2015-06-01

    Full Text Available This paper proposes a presentation unfolding regular and semi-regular polyhedra. Regular polyhedra are convex polyhedra whose faces are regular and equal polygons, with the same number of sides, and whose polyhedral angles are also regular and equal. Semi-regular polyhedra are convex polyhedra with regular polygon faces, several types and equal solid angles of the same type. A net of a polyhedron is a collection of edges in the plane which are the unfolded edges of the solid. Modeling and unfolding Platonic and Arhimediene polyhedra will be using 3dsMAX program. This paper is intended as an example of descriptive geometry applications.

  19. Lipschitz Regularity of Solutions for Mixed Integro-Differential Equations

    OpenAIRE

    Barles, Guy; Chasseigne, Emmanuel; Ciomaga, Adina; Imbert, Cyril

    2011-01-01

    We establish new Hoelder and Lipschitz estimates for viscosity solutions of a large class of elliptic and parabolic nonlinear integro-differential equations, by the classical Ishii-Lions's method. We thus extend the Hoelder regularity results recently obtained by Barles, Chasseigne and Imbert (2011). In addition, we deal with a new class of nonlocal equations that we term mixed integro-differential equations. These equations are particularly interesting, as they are degenerate both in the loc...

  20. 26 CFR 1.167(a)-11 - Depreciation based on class lives and asset depreciation ranges for property placed in service...

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Depreciation based on class lives and asset depreciation ranges for property placed in service after December 31, 1970. 1.167(a)-11 Section 1.167(a)-11...) INCOME TAXES (CONTINUED) Itemized Deductions for Individuals and Corporations § 1.167(a)-11 Depreciation...

  1. The Student with Albinism in the Regular Classroom.

    Science.gov (United States)

    Ashley, Julia Robertson

    This booklet, intended for regular education teachers who have children with albinism in their classes, begins with an explanation of albinism, then discusses the special needs of the student with albinism in the classroom, and presents information about adaptations and other methods for responding to these needs. Special social and emotional…

  2. Chiral Thirring–Wess model with Faddeevian regularization

    International Nuclear Information System (INIS)

    Rahaman, Anisur

    2015-01-01

    Replacing vector type of interaction of the Thirring–Wess model by the chiral type a new model is presented which is termed here as chiral Thirring–Wess model. Ambiguity parameters of regularization are so chosen that the model falls into the Faddeevian class. The resulting Faddeevian class of model in general does not possess Lorentz invariance. However we can exploit the arbitrariness admissible in the ambiguity parameters to relate the quantum mechanically generated ambiguity parameters with the classical parameter involved in the masslike term of the gauge field which helps to maintain physical Lorentz invariance instead of the absence of manifestly Lorentz covariance of the model. The phase space structure and the theoretical spectrum of this class of model have been determined through Dirac’s method of quantization of constraint system

  3. Regularity of p(ṡ)-superharmonic functions, the Kellogg property and semiregular boundary points

    Science.gov (United States)

    Adamowicz, Tomasz; Björn, Anders; Björn, Jana

    2014-11-01

    We study various boundary and inner regularity questions for $p(\\cdot)$-(super)harmonic functions in Euclidean domains. In particular, we prove the Kellogg property and introduce a classification of boundary points for $p(\\cdot)$-harmonic functions into three disjoint classes: regular, semiregular and strongly irregular points. Regular and especially semiregular points are characterized in many ways. The discussion is illustrated by examples. Along the way, we present a removability result for bounded $p(\\cdot)$-harmonic functions and give some new characterizations of $W^{1, p(\\cdot)}_0$ spaces. We also show that $p(\\cdot)$-superharmonic functions are lower semicontinuously regularized, and characterize them in terms of lower semicontinuously regularized supersolutions.

  4. Two-Stage Regularized Linear Discriminant Analysis for 2-D Data.

    Science.gov (United States)

    Zhao, Jianhua; Shi, Lei; Zhu, Ji

    2015-08-01

    Fisher linear discriminant analysis (LDA) involves within-class and between-class covariance matrices. For 2-D data such as images, regularized LDA (RLDA) can improve LDA due to the regularized eigenvalues of the estimated within-class matrix. However, it fails to consider the eigenvectors and the estimated between-class matrix. To improve these two matrices simultaneously, we propose in this paper a new two-stage method for 2-D data, namely a bidirectional LDA (BLDA) in the first stage and the RLDA in the second stage, where both BLDA and RLDA are based on the Fisher criterion that tackles correlation. BLDA performs the LDA under special separable covariance constraints that incorporate the row and column correlations inherent in 2-D data. The main novelty is that we propose a simple but effective statistical test to determine the subspace dimensionality in the first stage. As a result, the first stage reduces the dimensionality substantially while keeping the significant discriminant information in the data. This enables the second stage to perform RLDA in a much lower dimensional subspace, and thus improves the two estimated matrices simultaneously. Experiments on a number of 2-D synthetic and real-world data sets show that BLDA+RLDA outperforms several closely related competitors.

  5. Regular graph construction for semi-supervised learning

    International Nuclear Information System (INIS)

    Vega-Oliveros, Didier A; Berton, Lilian; Eberle, Andre Mantini; Lopes, Alneu de Andrade; Zhao, Liang

    2014-01-01

    Semi-supervised learning (SSL) stands out for using a small amount of labeled points for data clustering and classification. In this scenario graph-based methods allow the analysis of local and global characteristics of the available data by identifying classes or groups regardless data distribution and representing submanifold in Euclidean space. Most of methods used in literature for SSL classification do not worry about graph construction. However, regular graphs can obtain better classification accuracy compared to traditional methods such as k-nearest neighbor (kNN), since kNN benefits the generation of hubs and it is not appropriate for high-dimensionality data. Nevertheless, methods commonly used for generating regular graphs have high computational cost. We tackle this problem introducing an alternative method for generation of regular graphs with better runtime performance compared to methods usually find in the area. Our technique is based on the preferential selection of vertices according some topological measures, like closeness, generating at the end of the process a regular graph. Experiments using the global and local consistency method for label propagation show that our method provides better or equal classification rate in comparison with kNN

  6. 22 CFR 145.26 - Non-Federal audits.

    Science.gov (United States)

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 145.26 Non-Federal audits. (a) Recipients and subrecipients that are institutions of higher...

  7. 22 CFR 518.26 - Non-Federal audits.

    Science.gov (United States)

    2010-04-01

    ... AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 518.26 Non-Federal audits. (a) Recipients and subrecipients that are institutions of higher education or other non-profit organizations (including hospitals) shall...

  8. Automated Assume-Guarantee Reasoning for Omega-Regular Systems and Specifications

    Science.gov (United States)

    Chaki, Sagar; Gurfinkel, Arie

    2010-01-01

    We develop a learning-based automated Assume-Guarantee (AG) reasoning framework for verifying omega-regular properties of concurrent systems. We study the applicability of non-circular (AGNC) and circular (AG-C) AG proof rules in the context of systems with infinite behaviors. In particular, we show that AG-NC is incomplete when assumptions are restricted to strictly infinite behaviors, while AG-C remains complete. We present a general formalization, called LAG, of the learning based automated AG paradigm. We show how existing approaches for automated AG reasoning are special instances of LAG.We develop two learning algorithms for a class of systems, called infinite regular systems, that combine finite and infinite behaviors. We show that for infinity-regular systems, both AG-NC and AG-C are sound and complete. Finally, we show how to instantiate LAG to do automated AG reasoning for infinite regular, and omega-regular, systems using both AG-NC and AG-C as proof rules

  9. A Class of Large-Update and Small-Update Primal-Dual Interior-Point Algorithms for Linear Optimization

    NARCIS (Netherlands)

    Bai, Y.Q.; Lesaja, G.; Roos, C.; Wang, G.Q.; El Ghami, M.

    2008-01-01

    In this paper we present a class of polynomial primal-dual interior-point algorithms for linear optimization based on a new class of kernel functions. This class is fairly general and includes the classical logarithmic function, the prototype self-regular function, and non-self-regular kernel

  10. 22 CFR 226.26 - Non-Federal audits.

    Science.gov (United States)

    2010-04-01

    ... Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Post-award Requirements Financial and Program Management § 226.26 Non-Federal audits... organizations (including hospitals) shall be subject to the audit requirements contained in the Single Audit Act...

  11. 25 CFR 26.22 - May a tribe integrate Job Placement and Training funds into its Public Law 102-477 Plan?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false May a tribe integrate Job Placement and Training funds... THE INTERIOR HUMAN SERVICES JOB PLACEMENT AND TRAINING PROGRAM General Applicability § 26.22 May a tribe integrate Job Placement and Training funds into its Public Law 102-477 Plan? Yes, Indian tribes...

  12. 26 CFR 1.860G-1 - Definition of regular and residual interests.

    Science.gov (United States)

    2010-04-01

    ...) Call premium. An interest in a REMIC does not qualify as a regular interest if the terms of the interest entitle the holder of that interest to the payment of any premium that is determined with... by the sponsor, the issue price is its fair market value on the pricing date (as defined in § 1.860F...

  13. Variational analysis of regular mappings theory and applications

    CERN Document Server

    Ioffe, Alexander D

    2017-01-01

    This monograph offers the first systematic account of (metric) regularity theory in variational analysis. It presents new developments alongside classical results and demonstrates the power of the theory through applications to various problems in analysis and optimization theory. The origins of metric regularity theory can be traced back to a series of fundamental ideas and results of nonlinear functional analysis and global analysis centered around problems of existence and stability of solutions of nonlinear equations. In variational analysis, regularity theory goes far beyond the classical setting and is also concerned with non-differentiable and multi-valued operators. The present volume explores all basic aspects of the theory, from the most general problems for mappings between metric spaces to those connected with fairly concrete and important classes of operators acting in Banach and finite dimensional spaces. Written by a leading expert in the field, the book covers new and powerful techniques, whic...

  14. Group Projects in Interior Design Studio Classes: Peer Feedback Benefits

    Science.gov (United States)

    Jurado, Juan A.

    2011-01-01

    Group projects have been shown to be effective for providing peer feedback in classrooms. While students in regular enrollment classes benefit from peer feedback, low-enrollment classes face many challenges. This study compares peer feedback effectiveness between two interior design studio classes with different design projects. In one class,…

  15. CT urography: segmentation of urinary bladder using CLASS with local contour refinement

    International Nuclear Information System (INIS)

    Cha, Kenny; Hadjiiski, Lubomir; Chan, Heang-Ping; Caoili, Elaine M; Cohan, Richard H; Zhou, Chuan

    2014-01-01

    .0%, 3.8 ± 2.3 mm, 73.8 ± 13.4% respectively, for the test set. With CLASS only, the corresponding values were 75.1 ± 13.2%, 18.7 ± 19.5%, 22.5 ± 14.9%, 4.3 ± 2.2 mm, 71.0 ± 12.6%, respectively, for the training set and 67.3 ± 14.3%, 29.3 ± 15.9%, 29.4 ± 15.6%, 4.9 ± 2.6 mm, 65.0 ± 13.3%, respectively, for the test set. The differences between the two methods for all five measures were statistically significant (p < 0.001) for both the training and test sets. The results demonstrate the potential of CLASS with LCR for segmentation of the bladder. (paper)

  16. Isolation of a new anti-inflammatory 20, 21, 22, 23, 24, 25, 26, 27-octanorcucurbitacin-type triterpene from Ibervillea sonorae.

    Science.gov (United States)

    Jardón-Delgado, Angel; Magos-Guerrero, Gil Alfonso; Martínez-Vázquez, Mariano

    2014-01-01

    A new cucurbitane-type triterpene, 20, 21, 22, 23, 24, 25, 26, 27-octanorcucurbita-5-ene-3, 11, 16-trione (1), named kinoin D, was isolated from the roots of the medicinal plant Ibervillea sonorae, (wereque). The structure of 1 was established on the basis of extensive NMR and MS studies. In addition, the known kinoins B (3) and C (5) were isolated, as were 16alpha-20,25-trihydroxy-3alpha-(2-O-alpha-L-rhamnopyranosiyl-D-glucopyranosyloxy)-(10alpha)-cucurbit-5-en-11,22-dione (6), (22S)-16alpha,22-diacetoxy-20,25-dihydroxy-3alpha-[3,4,6-tri-O-acetyl-2-O-(2,3,4-tri-O-acetyl-alpha-L-rhamnopyranosyl)-beta-glucopyranosyl]-(10alpha)-cucurbita-5,23t-dien-11-one (7) and 16alpha-acetoxy-20,25-dihydroxy-3alpha-[3,4,6-tri-O-acetyl-2-O-(2,3,4,-tri-O-acetyl-alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl]-(10alpha)-cucurbita-5-ene-11,22-dione (8). Compound 1 exhibited anti-inflammatory activity in TPA-induced edema in mice.

  17. Constitutional chromosomal events at 22q11 and 15q26 in a child with a pilocytic astrocytoma of the spinal cord.

    Science.gov (United States)

    Mascelli, Samantha; Severino, Mariasavina; Raso, Alessandro; Nozza, Paolo; Tassano, Elisa; Morana, Giovanni; De Marco, Patrizia; Merello, Elisa; Milanaccio, Claudia; Pavanello, Marco; Rossi, Andrea; Cama, Armando; Garrè, Maria Luisa; Capra, Valeria

    2014-01-01

    We report on a 9-years-old patient with mild intellectual disability, facial dimorphisms, bilateral semicircular canal dysplasia, periventricular nodular heterotopias, bilateral hippocampal malrotation and abnormal cerebellar foliation, who developed mild motor impairment and gait disorder due to a pilocytic astrocytoma of the spinal cord. Array-CGH analysis revealed two paternal inherited chromosomal events: a 484.3 Kb duplication on chromosome 15q26.3 and a 247 Kb deletion on 22q11.23. Further, a second de novo 1.5 Mb deletion on 22q11.21 occurred. Chromosome 22 at q11.2 and chromosome 15 at q24q26 are considered unstable regions subjected to copy number variations, i.e. structural alterations of genome, mediated by low copy repeat sequences or segmental duplications. The link between some structural CNVs, which compromise fundamental processes controlling DNA stability, and genomic disorders suggest a plausible scenario for cancer predisposition. Evaluation of the genes at the breakpoints cannot account simultaneously for the phenotype and tumour development in this patient. The two paternal inherited CNVs arguably are not pathogenic and do not contribute to the clinical manifestations. Similarly, although the de novo large deletion at 22q11.21 overlaps with the Di George (DGS) critical region and results in haploinsufficiency of genes compromising critical processes for DNA stability, this case lacks several hallmarks of DGS.

  18. Critical Behavior of the Annealed Ising Model on Random Regular Graphs

    Science.gov (United States)

    Can, Van Hao

    2017-11-01

    In Giardinà et al. (ALEA Lat Am J Probab Math Stat 13(1):121-161, 2016), the authors have defined an annealed Ising model on random graphs and proved limit theorems for the magnetization of this model on some random graphs including random 2-regular graphs. Then in Can (Annealed limit theorems for the Ising model on random regular graphs, arXiv:1701.08639, 2017), we generalized their results to the class of all random regular graphs. In this paper, we study the critical behavior of this model. In particular, we determine the critical exponents and prove a non standard limit theorem stating that the magnetization scaled by n^{3/4} converges to a specific random variable, with n the number of vertices of random regular graphs.

  19. Yang-Mills theories in axial and light-cone gauges, analytic regularization and Ward identities

    International Nuclear Information System (INIS)

    Lee, H.C.

    1984-12-01

    The application of the principles of generalization and analytic continuation to the regularization of divergent Feynman integrals is discussed. The technique, or analytic regularization, which is a generalization of dimensional regularization, is used to derive analytic representations for two classes of massless two-point integrals. The first class is based on the principal-value prescription and includes integrals encountered in quantum field theories in the ghost-free axial gauge (n.A=0), reducing in a special case to integrals in the light-cone gauge (n.A=0,n 2 =0). The second class is based on the Mandelstam prescription devised espcially for the light-cone gauge. For some light-cone gauge integrals the two representations are not equivalent. Both classes include as a subclass integrals in the Lorentz covariant 'zeta-gauges'. The representations are used to compute one-loop corrections to the self-energy and the three-vertex in Yang-Mills theories in the axial and light-cone gauges, showing that the two- and three-point Ward identities are satisfied; to illustrate that ultraviolet and infrared singularities, indistinguishable in dimensional regularization, can be separated analytically; and to show that certain tadpole integrals vanish because of an exact cancellation between ultraviolet and infrared singularities. In the axial gauge, the wavefunction and vertex renormalization constants, Z 3 and Z 1 , are identical, so that the β-function can be directly derived from Z 3 the result being the same as that computed in the covariant zeta-gauges. Preliminary results suggest that the light-cone gauge in the Mandelstam prescription, but not in the principal value prescription, has the same renormalization property of the axial gauge

  20. The Role of PPK26 in Drosophila Larval Mechanical Nociception

    Directory of Open Access Journals (Sweden)

    Yanmeng Guo

    2014-11-01

    Full Text Available In Drosophila larvae, the class IV dendritic arborization (da neurons are polymodal nociceptors. Here, we show that ppk26 (CG8546 plays an important role in mechanical nociception in class IV da neurons. Our immunohistochemical and functional results demonstrate that ppk26 is specifically expressed in class IV da neurons. Larvae with mutant ppk26 showed severe behavioral defects in a mechanical nociception behavioral test but responded to noxious heat stimuli comparably to wild-type larvae. In addition, functional studies suggest that ppk26 and ppk (also called ppk1 function in the same pathway, whereas piezo functions in a parallel pathway. Consistent with these functional results, we found that PPK and PPK26 are interdependent on each other for their cell surface localization. Our work indicates that PPK26 and PPK might form heteromeric DEG/ENaC channels that are essential for mechanotransduction in class IV da neurons.

  1. A new approach to nonlinear constrained Tikhonov regularization

    KAUST Repository

    Ito, Kazufumi

    2011-09-16

    We present a novel approach to nonlinear constrained Tikhonov regularization from the viewpoint of optimization theory. A second-order sufficient optimality condition is suggested as a nonlinearity condition to handle the nonlinearity of the forward operator. The approach is exploited to derive convergence rate results for a priori as well as a posteriori choice rules, e.g., discrepancy principle and balancing principle, for selecting the regularization parameter. The idea is further illustrated on a general class of parameter identification problems, for which (new) source and nonlinearity conditions are derived and the structural property of the nonlinearity term is revealed. A number of examples including identifying distributed parameters in elliptic differential equations are presented. © 2011 IOP Publishing Ltd.

  2. Partial Regularity for Holonomic Minimisers of Quasiconvex Functionals

    Science.gov (United States)

    Hopper, Christopher P.

    2016-10-01

    We prove partial regularity for local minimisers of certain strictly quasiconvex integral functionals, over a class of Sobolev mappings into a compact Riemannian manifold, to which such mappings are said to be holonomically constrained. Our approach uses the lifting of Sobolev mappings to the universal covering space, the connectedness of the covering space, an application of Ekeland's variational principle and a certain tangential A-harmonic approximation lemma obtained directly via a Lipschitz approximation argument. This allows regularity to be established directly on the level of the gradient. Several applications to variational problems in condensed matter physics with broken symmetries are also discussed, in particular those concerning the superfluidity of liquid helium-3 and nematic liquid crystals.

  3. User modeling, adaptation, and personalization : 17th international conference, UMAP 2009, formerly UM and AH, Trento, Italy, June 22-26, 2009 : proceedings

    NARCIS (Netherlands)

    Houben, G.J.P.M.; McCalla, G.I.; Pianesi, F.; Zancanaro, M.

    2009-01-01

    The First International Conference on User Modeling, Adaptation, and Personalization (UMAP 2009) was held June 22-26, 2009, in Trento, Italy. UMAP 2009 was not, however, the first conference on user modeling or adaptation. In fact, UMAP 2009 merged two vigorous biennial conference traditions - the

  4. SUPPORTTING REGULAR AND ON-LINE BIOCHEMISTRY CLASSES USING INTERACTIVE LEARNING

    Directory of Open Access Journals (Sweden)

    F.C. Dórea

    2004-05-01

    Full Text Available Interactive learning on the Web may be a way to partially supplement the classroom learning ex-perience by providing an interactive environment similar to the classroom but with more attentionto individual student needs. New computational resources are available every day, and these newtechnologies that help the understanding process can be popularized by free full access web sites, asBiochemical View. This site, available at http://www.unb.br/cbsp/bioq, was developed at Universityof Braslia (UnB to support Biochemistry classes of this and any other Universities, since its alsoavailable in an English version. The contents - that include the usual metabolic pathways referentto the metabolism of carbohydrates, amino acids, lipids and nucleic acids - are presented in bi andthree-dimensional formats, easily accessible and assimilable, complemented with objective texts anddescription of regulation points. Protocols for experimental classes, reference materials, and specicinformation about each molecule of all pathways are also available, including metabolic participationschemes of them. An evaluation form of the site is available on-line, developed using PHP. Besidesthe positives results, the suggestions collected in these evaluations since 2001 have been guiding theactualizations. So, the site is the result of students opinions and needs.

  5. Diverse Regular Employees and Non-regular Employment (Japanese)

    OpenAIRE

    MORISHIMA Motohiro

    2011-01-01

    Currently there are high expectations for the introduction of policies related to diverse regular employees. These policies are a response to the problem of disparities between regular and non-regular employees (part-time, temporary, contract and other non-regular employees) and will make it more likely that workers can balance work and their private lives while companies benefit from the advantages of regular employment. In this paper, I look at two issues that underlie this discussion. The ...

  6. PERCEPÇÕES DOS ALUNOS COM DEFICIÊNCIA INTELECTUAL SOBRE SUA MATRÍCULA NA CLASSE ESPECIAL E CLASSE COMUM. INTELLECTUALLY DISABLED STUDENTS’ PERCEPTIONS ABOUT THEIR ENROLLMENT IN SPECIAL CLASSES AND COMMON CLASSES

    Directory of Open Access Journals (Sweden)

    Mendes, Enicéia Gonçalves

    2011-11-01

    Full Text Available Tendo em vista a necessidade de avaliar e monitorar as práticas advindas da política da inclusão escolar em nosso país, principalmente por meio da opinião e percepção dos principais atores envolvidos neste processo, que são os alunos, o objetivo deste estudo é identificar as percepções de alunos com deficiência intelectual egressos de classe/escola especial e matriculados na classe comum de uma escola regular a respeito da classe/escola especial e o seu lugar de preferência para frequentar. O estudo foi desenvolvido numa cidade de médio porte do interior do estado de São Paulo e no total participaram 10 alunos com deficiência intelectual egressos de três escolas da rede de ensino municipal. Os resultados indicam que os alunos, apesar da experiência positiva na classe/escola especial, têm preferência pela matrícula na classe comum o que evidencia impacto positivo da política da inclusão escolar e também da necessidade de ouvirmos os estudantes para avaliarmos as práticas de inclusão escolar desenvolvidas.There is a need to assess and monitor the school inclusion policy and the uses deriving from it. This can be done primarily through the opinion and perception of the people involved in this process, the students. The objective of this study is to identify the perception of students with intellectual disability from special classes/schools and classmates from the current common classes about their opinion of special classes/schools and the place they chose to attend. The study was made in three schools of the municipal network of a midsize city in the state of São Paulo and ten students with intellectual disabilities from special classes/schools took part in it. The results show that the students, despite the positive experience in the special classes/schools, prefer to attend the regular classes, showing a positive impact of inclusion policy and also the need of listening to the students in order to evaluate the

  7. Molecular cloning of a cDNA and chromosomal localization of a human theta-class glutathione S-transferase gene (GSTT2) to chromosome 22

    Energy Technology Data Exchange (ETDEWEB)

    Tan, K.L.; Baker, R.T.; Board, P.G. [Australian National Univ., Canberra (Australia)] [and others

    1995-01-20

    Until recently the Theta-class glutathione S-transferases (GSTs) were largely overlooked due to their low activity with the model substrate 1-chloro-2,4-dinitrobenzene (CDNB) and their failure to bind to immobilized glutathione affinity matrices. Little is known about the number of genes in this class. Recently, Pemble et al. reported the cDNA cloning of a human Theta-class GST, termed GSTT1. In this study, we describe the molecular cloning of a cDNA encoding a second human Theta-class GST (GSTT2) from a {lambda}gt11 human liver 5{prime}-stretch cDNA library. The encoded protein contains 244 amino acids and has 78.3% sequence identity with the rat subunit 12 and only 55.0% identity with human GSTT1. GSTT2 has been mapped to chromosome 22 by somatic cell hybrid analysis. The precise position of the gene was localized to subband 22q11.2 by in situ hybridization. The absence of other regions of hybridization suggests that there are no closely related sequences (e.g., reverse transcribed pseudogenes) scattered throughout the genome and that if there are closely related genes, they must be clustered near GSTT2. Southern blot analysis of human DNA digested with BamHI shows that the size of the GSTT2 gene is relatively small, as the coding sequence falls within a 3.6-kb BamHI fragment. 35 refs., 6 figs.

  8. Alkylation of 2,6-di-tert-butylphenol with methyl acrylate catalyzed by potassium-2,6-di-tert-butylphenoxide

    OpenAIRE

    Zaikov, Gennady; Volod’kin, Alexander

    2010-01-01

    The kinetics of catalytic alkylation of 2,6-ditert- butylphenol (ArOH) with methyl acrylate (MA) in the presence of potassium 2,6-di-tert-butylphenoxide (ArOK) depends on the method for the preparation of ArOK. The reaction ofArOH withKOHat temperatures > 453 Kaffords monomeric ArOK, which properties differ from those in the case of potassium 2,6-di-tert-butylphenoxide synthesized by the earliermethods.The regularities ofArOH alkylation depend ontheArOKconcentration, theArOH...

  9. Instabilities of the zeta-function regularization in the presence of symmetries

    International Nuclear Information System (INIS)

    Rasetti, M.

    1980-01-01

    The zeta-function regularization method requires the calculation of the spectrum-generating function zeta sub(M) of a generic real, elliptic, self-adjoint differential operator on a manifold M. An asymptotic expansion for zeta sub(M) is given for the class of all symmetric spaces of rank 1, sufficient to compute its Mellin transform and deduce the regularization of the corresponding quadratic path integrals. The summability properties of the generalized zeta-function introduce physical instabilities in the system as negative specific heat. The technique (and the instability as well) is shown to hold - under the assumed symmetry properties - in any dimension (preserving both the global and local properties of the manifold, as opposed to the dimensional regularization, where one adds extra flat dimensions only). (author)

  10. Age-related patterns of drug use initiation among polydrug using regular psychostimulant users.

    Science.gov (United States)

    Darke, Shane; Kaye, Sharlene; Torok, Michelle

    2012-09-01

    To determine age-related patterns of drug use initiation, drug sequencing and treatment entry among regular psychostimulant users. Cross-sectional study of 269 regular psychostimulant users, administered a structured interview examining onset of use for major licit and illicit drugs. The mean age at first intoxication was not associated with age or gender. In contrast, younger age was associated with earlier ages of onset for all of the illicit drug classes. Each additional year of age was associated with a 4 month increase in onset age for methamphetamine, and 3 months for heroin. By the age of 17, those born prior to 1961 had, on average, used only tobacco and alcohol, whereas those born between 1986 and 1990 had used nine different drug classes. The period between initial use and the transition to regular use, however, was stable. Age was also negatively correlated with both age at initial injection and regular injecting. Onset sequences, however, remained stable. Consistent with the age-related patterns of drug use, each additional year of age associated with a 0.47 year increase in the age at first treatment. While the age at first intoxication appeared stable, the trajectory through illicit drug use was substantially truncated. The data indicate that, at least among those who progress to regular illicit drug use, younger users are likely to be exposed to far broader polydrug use in their teens than has previously been the case. © 2012 Australasian Professional Society on Alcohol and other Drugs.

  11. MORE MINUTES OF PHYSICAL EDUCATION CLASSES SUPPORT MOTOR DEVELOPMENT IN PRESCHOOL CHILDREN

    Directory of Open Access Journals (Sweden)

    Judith Jiménez Díaz

    2010-12-01

    Full Text Available The aim of this study was to determine the effect of physical education classes in 12 fundamental motor skills (FMS. Preschool students (M = 6.09±0.5 years old were randomly assigned to a control group (6 boys and 7 girls who performed the regular preschool class (which includes one 30- minutes session per week; experimental group 1 (6 boys and 6 girls who received the regular preschool class plus 1 session of 30 minutes per week of the intervention program; or experimental group 2 (6 boys and 7 girls, who received the regular preschool class plus 1 session of 60 minutes per week of the intervention program; during 8 weeks (n=38. All participants performed the Test of Gross Motor Development (TGMD-2 before and after the study. A one-way MANOVA reflected a similar behavior in al FMS in the pre-test. A two-way MANOVA (group x time reflected no interaction in the 12 FMS; also in the 6 object control FMS; but there was an interaction in the 6 locomotor FMS. In conclusion, 90-minutes of physical education classes per week only benefit the FMS of galloping and hopping.

  12. 40 CFR 264.317 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Science.gov (United States)

    2010-07-01

    ... HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Landfills § 264.317 Special requirements for... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.317 Section 264.317 Protection of Environment...

  13. 40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Science.gov (United States)

    2010-07-01

    ... HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment § 264.283 Special requirements... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment...

  14. Strategies for Teaching and Managing Large Classes in University ...

    African Journals Online (AJOL)

    Followed by 'automate assessment tasks where possible (e.g. online quizzes)' with (Mean 3.0, SD = .899) (effective assessment practices) and 'evaluating student understanding regularly through Mini quizzes, short test, class work or True/False responses' with (Mean 2.8, SD = .752) (managing and teaching large classes).

  15. English Teaching and Learning in Brazilian Regular Schools and Language Schools: A Study on Teachers' Beliefs

    Science.gov (United States)

    Fragozo, Carina Silva; Monawar, Mônica Deitos Stedile

    2012-01-01

    This paper aims to diagnose, through a qualitative comparative study, the main differences concerning the teaching of English in Brazilian regular schools when compared to language schools. There has been a growing tendency of students to attend language schools while still having English classes at their regular schools, and this has led to a lot…

  16. A regularization of the Burgers equation using a filtered convective velocity

    International Nuclear Information System (INIS)

    Norgard, Greg; Mohseni, Kamran

    2008-01-01

    This paper examines the properties of a regularization of the Burgers equation in one and multiple dimensions using a filtered convective velocity, which we have dubbed as the convectively filtered Burgers (CFB) equation. A physical motivation behind the filtering technique is presented. An existence and uniqueness theorem for multiple dimensions and a general class of filters is proven. Multiple invariants of motion are found for the CFB equation which are shown to be shared with the viscous and inviscid Burgers equations. Traveling wave solutions are found for a general class of filters and are shown to converge to weak solutions of the inviscid Burgers equation with the correct wave speed. Numerical simulations are conducted in 1D and 2D cases where the shock behavior, shock thickness and kinetic energy decay are examined. Energy spectra are also examined and are shown to be related to the smoothness of the solutions. This approach is presented with the hope of being extended to shock regularization of compressible Euler equations

  17. Coordinate-invariant regularization

    International Nuclear Information System (INIS)

    Halpern, M.B.

    1987-01-01

    A general phase-space framework for coordinate-invariant regularization is given. The development is geometric, with all regularization contained in regularized DeWitt Superstructures on field deformations. Parallel development of invariant coordinate-space regularization is obtained by regularized functional integration of the momenta. As representative examples of the general formulation, the regularized general non-linear sigma model and regularized quantum gravity are discussed. copyright 1987 Academic Press, Inc

  18. Do the majority of South Africans regularly consult traditional healers?

    Directory of Open Access Journals (Sweden)

    Gabriel Louw

    2016-12-01

    Full Text Available Background The statutory recognition of traditional healers as healthcare practitioners in South Africa in terms of the Traditional Health Practitioners Act 22 of 2007 is based on various assumptions, opinions and generalizations. One of the prominent views is that the majority of South Africans regularly consult traditional healers. It even has been alleged that this number can be as high as 80 per cent of the South African population. For medical doctors and other health practitioners registered with the Health Professions Council of South Africa (HPCSA, this new statutory status of traditional health practitioners, means the required presence of not only a healthcare competitor that can overstock the healthcare market with service lending, medical claims and healthcare costs, but also a competitor prone to malpractice. Aims The study aimed to determine if the majority of South Africans regularly consult traditional healers. Methods This is an exploratory and descriptive study following the modern historical approach of investigation and literature review. The emphasis is on using current documentation like articles, books and newspapers, as primary sources to determine if the majority of South Africans regularly consult traditional healers. The findings are offered in narrative form. Results It is clear that there is no trustworthy statistics on the percentages of South Africans using traditional healers. A scientific survey is needed to determine the extent to which traditional healers are consulted. This will only be possible after the Traditional Health Practitioners Act No 22 has been fully enacted and traditional health practitioners have become fully active in the healthcare sector. Conclusion In poorer, rural areas no more than 11.2 per cent of the South African population regularly consult traditional healers, while the figure for the total population seems to be no more than 1.4 per cent. The argument that the majority of South

  19. 32 CFR 1630.43 - Class 4-D: Minister of religion.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Class 4-D: Minister of religion. 1630.43 Section... CLASSIFICATION RULES § 1630.43 Class 4-D: Minister of religion. In accord with part 1645 of this chapter any registrant shall be placed in Class 4-D who is a: (a) Duly ordained minister of religion; or (b) Regular...

  20. Nordic Walking Classes

    CERN Multimedia

    Fitness Club

    2015-01-01

    Four classes of one hour each are held on Tuesdays. RDV barracks parking at Entrance A, 10 minutes before class time. Spring Course 2015: 05.05/12.05/19.05/26.05 Prices 40 CHF per session + 10 CHF club membership 5 CHF/hour pole rental Check out our schedule and enroll at: https://espace.cern.ch/club-fitness/Lists/Nordic%20Walking/NewForm.aspx? Hope to see you among us! fitness.club@cern.ch

  1. Output regularization of SVM seizure predictors: Kalman Filter versus the "Firing Power" method.

    Science.gov (United States)

    Teixeira, Cesar; Direito, Bruno; Bandarabadi, Mojtaba; Dourado, António

    2012-01-01

    Two methods for output regularization of support vector machines (SVMs) classifiers were applied for seizure prediction in 10 patients with long-term annotated data. The output of the classifiers were regularized by two methods: one based on the Kalman Filter (KF) and other based on a measure called the "Firing Power" (FP). The FP is a quantification of the rate of the classification in the preictal class in a past time window. In order to enable the application of the KF, the classification problem was subdivided in a two two-class problem, and the real-valued output of SVMs was considered. The results point that the FP method raise less false alarms than the KF approach. However, the KF approach presents an higher sensitivity, but the high number of false alarms turns their applicability negligible in some situations.

  2. Selection of regularization parameter for l1-regularized damage detection

    Science.gov (United States)

    Hou, Rongrong; Xia, Yong; Bao, Yuequan; Zhou, Xiaoqing

    2018-06-01

    The l1 regularization technique has been developed for structural health monitoring and damage detection through employing the sparsity condition of structural damage. The regularization parameter, which controls the trade-off between data fidelity and solution size of the regularization problem, exerts a crucial effect on the solution. However, the l1 regularization problem has no closed-form solution, and the regularization parameter is usually selected by experience. This study proposes two strategies of selecting the regularization parameter for the l1-regularized damage detection problem. The first method utilizes the residual and solution norms of the optimization problem and ensures that they are both small. The other method is based on the discrepancy principle, which requires that the variance of the discrepancy between the calculated and measured responses is close to the variance of the measurement noise. The two methods are applied to a cantilever beam and a three-story frame. A range of the regularization parameter, rather than one single value, can be determined. When the regularization parameter in this range is selected, the damage can be accurately identified even for multiple damage scenarios. This range also indicates the sensitivity degree of the damage identification problem to the regularization parameter.

  3. Duality and modular class of a Nambu-Poisson structure

    International Nuclear Information System (INIS)

    Ibanez, R.; Leon, M. de; Lopez, B.; Marrero, J.C.; Padron, E.

    2001-01-01

    In this paper we introduce cohomology and homology theories for Nambu-Poisson manifolds. Also we study the relation between the existence of a duality for these theories and the vanishing of a particular Nambu-Poisson cohomology class, the modular class. The case of a regular Nambu-Poisson structure and some singular examples are discussed. (author)

  4. Regularity for 3D Navier-Stokes equations in terms of two components of the vorticity

    Directory of Open Access Journals (Sweden)

    Sadek Gala

    2010-10-01

    Full Text Available We establish regularity conditions for the 3D Navier-Stokes equation via two components of the vorticity vector. It is known that if a Leray-Hopf weak solution $u$ satisfies $$ ilde{omega}in L^{2/(2-r}(0,T;L^{3/r}(mathbb{R}^3quad hbox{with }0regularity of Leray-Hopf weak solution $u$ under each of the following two (weaker conditions: $$displaylines{ ilde{omega}in L^{2/(2-r}(0,T;dot {mathcal{M}}_{2, 3/r}(mathbb{R}^3quad hbox{for }02/(2-r}(0,T;dot {mathcal{M}}_{2, 3/r}(mathbb{R}^3quad hbox{for }0leq r<1, }$$ where $dot {mathcal{M}}_{2,3/r}(mathbb{R}^3$ is the Morrey-Campanato space. Since $L^{3/r}(mathbb{R}^3$ is a proper subspace of $dot {mathcal{M}}_{2,3/r}(mathbb{R}^3$, our regularity criterion improves the results in Chae-Choe [5].

  5. Pade approximants for entire functions with regularly decreasing Taylor coefficients

    International Nuclear Information System (INIS)

    Rusak, V N; Starovoitov, A P

    2002-01-01

    For a class of entire functions the asymptotic behaviour of the Hadamard determinants D n,m as 0≤m≤m(n)→∞ and n→∞ is described. This enables one to study the behaviour of parabolic sequences from Pade and Chebyshev tables for many individual entire functions. The central result of the paper is as follows: for some sequences {(n,m(n))} in certain classes of entire functions (with regular Taylor coefficients) the Pade approximants {π n,m(n) }, which provide the locally best possible rational approximations, converge to the given function uniformly on the compact set D={z:|z|≤1} with asymptotically best rate

  6. Imbalanced class learning in epigenetics.

    Science.gov (United States)

    Haque, M Muksitul; Skinner, Michael K; Holder, Lawrence B

    2014-07-01

    In machine learning, one of the important criteria for higher classification accuracy is a balanced dataset. Datasets with a large ratio between minority and majority classes face hindrance in learning using any classifier. Datasets having a magnitude difference in number of instances between the target concept result in an imbalanced class distribution. Such datasets can range from biological data, sensor data, medical diagnostics, or any other domain where labeling any instances of the minority class can be time-consuming or costly or the data may not be easily available. The current study investigates a number of imbalanced class algorithms for solving the imbalanced class distribution present in epigenetic datasets. Epigenetic (DNA methylation) datasets inherently come with few differentially DNA methylated regions (DMR) and with a higher number of non-DMR sites. For this class imbalance problem, a number of algorithms are compared, including the TAN+AdaBoost algorithm. Experiments performed on four epigenetic datasets and several known datasets show that an imbalanced dataset can have similar accuracy as a regular learner on a balanced dataset.

  7. Male Eating Disorder Symptom Patterns and Health Correlates From 13 to 26 Years of Age

    Science.gov (United States)

    Calzo, Jerel P.; Horton, Nicholas J.; Sonneville, Kendrin R.; Swanson, Sonja; Crosby, Ross D.; Micali, Nadia; Eddy, Kamryn T.; Field, Alison E.

    2016-01-01

    Objective Research on the manifestations and health correlates of eating disorder symptoms among males is lacking. This study identified patterns of appearance concerns and eating disorder behaviors from adolescence through young adulthood and their health correlates. Method Participants were 7,067 males from the prospective Growing Up Today Study. Surveys from 1999–2007 (spanning ages 13–26 years) provided repeated measures data on: muscularity and leanness concerns; eating disorder behaviors (purging, overeating, binge eating, use of muscle-building products); and health correlates (obesity, non-marijuana drug use, binge drinking, and depressive symptoms). Results Latent class analyses of observations at ages 13–15, 16–18, 19–22, and 23–26 identified one large Asymptomatic class and four symptomatic patterns: Body Image Disturbance (high appearance concerns, low eating disorder behaviors; 1.0%–6.0% per age period); Binge Eating/Purging (binge eating and purging, use of muscle-building products, low appearance concerns; 0.1%–2.5%); Mostly Asymptomatic (low levels of muscularity concern, product use, and overeating; 3.5%–5.0%); and Muscularity Concerns (high muscularity concerns and use of products; 0.6%–1.0%). The Body Image Disturbance class was associated with high estimated prevalence of depressive symptoms. Males in the Binge Eating/Purging and Muscularity Concerns classes had high prevalence of binge drinking and drug use. Despite exhibiting modestly greater appearance concerns and eating disorder behaviors than the Asymptomatic class, being in the Mostly Asymptomatic class was prospectively associated with adverse health outcomes. Conclusion Results underscore the importance of measuring concerns about leanness, muscularity, and use of muscle-building products when assessing eating disorder presentations among males in research and clinical settings. PMID:27453083

  8. Effect of Ag addition on phase transitions of the Cu–22.26 at.%Al–9.93 at.%Mn alloy

    Energy Technology Data Exchange (ETDEWEB)

    Silva, R.A.G., E-mail: galdino.ricardo@gmail.com [DCET, Universidade Federal de São Paulo, Campus Diadema, SP (Brazil); Gama, S.; Paganotti, A. [DCET, Universidade Federal de São Paulo, Campus Diadema, SP (Brazil); Adorno, A.T.; Carvalho, T.M.; Santos, C.M.A. [DFQ, Instituto de Química – Unesp, Campus Araraquara, SP (Brazil)

    2013-02-20

    Highlights: ► A kinetic mechanism for the dissolution of DO{sub 3} phase is suggested. ► The intermediate phase interferes on the kinetics of the DO{sub 3} phase dissolution. ► The presence of Ag changes the stability of intermediate phase. - Abstract: The phase transitions that occur in the Cu–22.26 at.%Al–9.93 at.%Mn and Cu–22.49 at.%Al–10.01 at.%Mn–1.53 at.%Ag alloys after slow cooling were studied using differential scanning calorimetry at different heating rates, microhardness changes with temperature, magnetization changes with temperature, scanning electron microscopy and energy dispersion X-ray spectroscopy. The results indicated that the presence of Ag does not modify the transition sequence of Cu–Al–Mn alloy, introduces a new transition due to the (Ag-Cu)-rich precipitates dissolution at about 800 K, and changes the mechanism of DO{sub 3} phase dissolution. This mechanistic change was analyzed and a sequence of phase transitions was proposed for the reaction.

  9. Abstracts of oral and poster presentations given at the Ascochyta 2012 Workshop, Córdoba, Spain, 2226 April 2012

    Directory of Open Access Journals (Sweden)

    Teresa Millan

    2013-05-01

    Full Text Available The third International Ascochyta Workshop was held in Córdoba, Spain 22 - 26 April 2012. This meeting was attended by 70 participants, and 33 oral presentations, 17 posters and 4 invited speeches were presented dealing with Ascochyta blights of the cool season food legumes (peas, lentils, chickpeas and faba beans. In addition, a special session was held on “Food legumes Research in North Africa”. Abstracts of the oral presentations and the posters of the congress are presented in this issue.

  10. Borderline personality disorder and regularly drinking alcohol before sex.

    Science.gov (United States)

    Thompson, Ronald G; Eaton, Nicholas R; Hu, Mei-Chen; Hasin, Deborah S

    2017-07-01

    Drinking alcohol before sex increases the likelihood of engaging in unprotected intercourse, having multiple sexual partners and becoming infected with sexually transmitted infections. Borderline personality disorder (BPD), a complex psychiatric disorder characterised by pervasive instability in emotional regulation, self-image, interpersonal relationships and impulse control, is associated with substance use disorders and sexual risk behaviours. However, no study has examined the relationship between BPD and drinking alcohol before sex in the USA. This study examined the association between BPD and regularly drinking before sex in a nationally representative adult sample. Participants were 17 491 sexually active drinkers from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions. Logistic regression models estimated effects of BPD diagnosis, specific borderline diagnostic criteria and BPD criterion count on the likelihood of regularly (mostly or always) drinking alcohol before sex, adjusted for controls. Borderline personality disorder diagnosis doubled the odds of regularly drinking before sex [adjusted odds ratio (AOR) = 2.26; confidence interval (CI) = 1.63, 3.14]. Of nine diagnostic criteria, impulsivity in areas that are self-damaging remained a significant predictor of regularly drinking before sex (AOR = 1.82; CI = 1.42, 2.35). The odds of regularly drinking before sex increased by 20% for each endorsed criterion (AOR = 1.20; CI = 1.14, 1.27) DISCUSSION AND CONCLUSIONS: This is the first study to examine the relationship between BPD and regularly drinking alcohol before sex in the USA. Substance misuse treatment should assess regularly drinking before sex, particularly among patients with BPD, and BPD treatment should assess risk at the intersection of impulsivity, sexual behaviour and substance use. [Thompson Jr RG, Eaton NR, Hu M-C, Hasin DS Borderline personality disorder and regularly drinking alcohol

  11. Expanding the boundaries of evaluative learning research: how intersecting regularities shape our likes and dislikes

    OpenAIRE

    Hughes, Sean Joseph; De Houwer, Jan; Perugini, Marco

    2016-01-01

    Over the last 30 years, researchers have identified several types of procedures through which novel preferences may be formed and existing ones altered. For instance, regularities in the presence of a single stimulus (as in the case of mere exposure) or 2 or more stimuli (as in the case of evaluative conditioning) have been shown to influence liking. We propose that intersections between regularities represent a previously unrecognized class of procedures for changing liking. Across 4 related...

  12. Space Physics Strategy-Implementation Study. Volume 1. Goals, objectives, strategy. Report of Workshop 1. Held in Baltimore, Maryland on January 22-26, 1990 (second edition)

    International Nuclear Information System (INIS)

    1991-04-01

    This is the report of Workshop 1, January 22-26, 1990, Baltimore, Maryland. The document includes the Report of the Cosmic and Heliospheric Panel, Report of the Ionosphere-Thermosphere-Mesosphere Panel, Report of the Magnetospheric Physics Panel, Report of the Solar Physics Panel, Report of the Theory Panel

  13. 48 CFR 53.301-26 - Award/Contract.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Award/Contract. 53.301-26 Section 53.301-26 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Illustrations of Forms 53.301-26 Award/Contract. ER22AP08.000 [73 FR 21785, Apr...

  14. Impulsivity and related neuropsychological features in regular and addictive first person shooter gaming.

    Science.gov (United States)

    Metcalf, Olivia; Pammer, Kristen

    2014-03-01

    Putative cyber addictions are of significant interest. There remains little experimental research into excessive use of first person shooter (FPS) games, despite their global popularity. Moreover, the role between excessive gaming and impulsivity remains unclear, with previous research showing conflicting findings. The current study investigated performances on a number of neuropsychological tasks (go/no-go, continuous performance task, Iowa gambling task) and a trait measure of impulsivity for a group of regular FPS gamers (n=25), addicted FPS gamers (n=22), and controls (n=22). Gamers were classified using the Addiction-Engagement Questionnaire. Addicted FPS gamers had significantly higher levels of trait impulsivity on the Barratt Impulsiveness Scale compared to controls. Addicted FPS gamers also had significantly higher levels of disinhibition in a go/no-go task and inattention in a continuous performance task compared to controls, whereas the regular FPS gamers had better decision making on the Iowa gambling task compared to controls. The results indicate impulsivity is associated with FPS gaming addiction, comparable to pathological gambling. The relationship between impulsivity and excessive gaming may be unique to the FPS genre. Furthermore, regular FPS gaming may improve decision making ability.

  15. Teachers' Views about the Education of Gifted Students in Regular Classrooms

    Directory of Open Access Journals (Sweden)

    Neşe Kutlu Abu

    2017-12-01

    Full Text Available The purpose of this study was to investigate classroom teachers’ views about the education of gifted students in regular classrooms. The sample of the study is composed of ten primary school teachers working in the city of Amasya and had gifted students in their classes. In the present study, phenomenological research design was used. Data was collected through semi-structured interviews and analyzed descriptively in the QSR N-Vivo package program. The findings showed that teachers did not believe a need for differentiating curriculum for gifted students; rather they expressed that regular curriculum was enough for gifted students. Based on the findings, it is clear that teachers need training both on the need of differentiated education for gifted students and strategies and approaches about how to educate gifted students. Teachers’ attitudes towards gifted students in regular classrooms should be investigated so that teachers’ unsupportive beliefs about differentiation for gifted students also influence their attitudes towards gifted students.

  16. A Variance Minimization Criterion to Feature Selection Using Laplacian Regularization.

    Science.gov (United States)

    He, Xiaofei; Ji, Ming; Zhang, Chiyuan; Bao, Hujun

    2011-10-01

    In many information processing tasks, one is often confronted with very high-dimensional data. Feature selection techniques are designed to find the meaningful feature subset of the original features which can facilitate clustering, classification, and retrieval. In this paper, we consider the feature selection problem in unsupervised learning scenarios, which is particularly difficult due to the absence of class labels that would guide the search for relevant information. Based on Laplacian regularized least squares, which finds a smooth function on the data manifold and minimizes the empirical loss, we propose two novel feature selection algorithms which aim to minimize the expected prediction error of the regularized regression model. Specifically, we select those features such that the size of the parameter covariance matrix of the regularized regression model is minimized. Motivated from experimental design, we use trace and determinant operators to measure the size of the covariance matrix. Efficient computational schemes are also introduced to solve the corresponding optimization problems. Extensive experimental results over various real-life data sets have demonstrated the superiority of the proposed algorithms.

  17. Historical temperature and salinity data collected from 1896-04-22 to 1961-03-26 from the World Ocean and provided by United Kingdom hydrographic office (NODC Accession 0073673)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Historical temperature and salinity data collected from 1896-04-22 to 1961-03-26 from the World Ocean. Data were digitized from cards provided by United Kingdom...

  18. Giant regular polyhedra from calixarene carboxylates and uranyl

    Science.gov (United States)

    Pasquale, Sara; Sattin, Sara; Escudero-Adán, Eduardo C.; Martínez-Belmonte, Marta; de Mendoza, Javier

    2012-01-01

    Self-assembly of large multi-component systems is a common strategy for the bottom-up construction of discrete, well-defined, nanoscopic-sized cages. Icosahedral or pseudospherical viral capsids, built up from hundreds of identical proteins, constitute typical examples of the complexity attained by biological self-assembly. Chemical versions of the so-called 5 Platonic regular or 13 Archimedean semi-regular polyhedra are usually assembled combining molecular platforms with metals with commensurate coordination spheres. Here we report novel, self-assembled cages, using the conical-shaped carboxylic acid derivatives of calix[4]arene and calix[5]arene as ligands, and the uranyl cation UO22+ as a metallic counterpart, which coordinates with three carboxylates at the equatorial plane, giving rise to hexagonal bipyramidal architectures. As a result, octahedral and icosahedral anionic metallocages of nanoscopic dimensions are formed with an unusually small number of components. PMID:22510690

  19. Distribution of class 1 integrons with IS26-mediated deletions in their 3'-conserved segments in Escherichia coli of human and animal origin.

    Directory of Open Access Journals (Sweden)

    Fay E Dawes

    Full Text Available Class 1 integrons play a role in the emergence of multi-resistant bacteria by facilitating the recruitment of gene cassettes encoding antibiotic resistance genes. 512 E. coli strains sourced from humans (n = 202, animals (n = 304 and the environment (n = 6 were screened for the presence of the intI1 gene. In 31/79 integron positive E. coli strains, the gene cassette regions could not be PCR amplified using standard primers. DNA sequence analysis of 6 serologically diverse strains revealed atypical integrons harboured the dfrA5 cassette gene and only 24 bp of the integron 3'-conserved segment (CS remained, due to the insertion of IS26. PCR targeting intI1 and IS26 followed by restriction fragment length polymorphism (RFLP analysis identified the integron-dfrA5-IS26 element in 27 E. coli strains of bovine origin and 4 strains of human origin. Southern hybridization and transformation studies revealed the integron-dfrA5-IS26 gene arrangement was either chromosomally located or plasmid borne. Plasmid location in 4/9 E. coli strains and PCR linkage of Tn21 transposition genes with the intI1 gene in 20/31 strains, suggests this element is readily disseminated by horizontal transfer.

  20. The habitus professorial and special education: perceptions of common class teachers and resource room multifuncional

    Directory of Open Access Journals (Sweden)

    Norberto Kuhn Junior

    2016-10-01

    Full Text Available This article analyzes the Inclusive Education from the Specialized Educational Service (SES in Multifunctional Resources Classes (MRC in the Municipal Teaching web in Novo Hamburgo/RS. It counted with the participation of 99 teachers in the regular classroom who worked as teachers of students with disabilities, pervasive developmental disorders, high ability/gifted and 30 MRC teachers in 2013. The data showed that the MRC teachers shown to have minor difficulties in working with students from the Special Education than the teachers of regular class. Through the identification of the teachers’ habitus of regular class, it was understood that the difficulties indicated by them derive from the fragility in their pedagogical training to work with students of Special Education. It is about a non-inclusive habitus, which is constituted from the internalization of teaching models based on the subject homogenization (all are equal over the constitution of a new habitus, structural of a teaching model that recognizes the diversity for inclusion.

  1. Distance-regular graphs

    NARCIS (Netherlands)

    van Dam, Edwin R.; Koolen, Jack H.; Tanaka, Hajime

    2016-01-01

    This is a survey of distance-regular graphs. We present an introduction to distance-regular graphs for the reader who is unfamiliar with the subject, and then give an overview of some developments in the area of distance-regular graphs since the monograph 'BCN'[Brouwer, A.E., Cohen, A.M., Neumaier,

  2. Regular expressions cookbook

    CERN Document Server

    Goyvaerts, Jan

    2009-01-01

    This cookbook provides more than 100 recipes to help you crunch data and manipulate text with regular expressions. Every programmer can find uses for regular expressions, but their power doesn't come worry-free. Even seasoned users often suffer from poor performance, false positives, false negatives, or perplexing bugs. Regular Expressions Cookbook offers step-by-step instructions for some of the most common tasks involving this tool, with recipes for C#, Java, JavaScript, Perl, PHP, Python, Ruby, and VB.NET. With this book, you will: Understand the basics of regular expressions through a

  3. Abel transforms with low regularity with applications to x-ray tomography on spherically symmetric manifolds

    Science.gov (United States)

    de Hoop, Maarten V.; Ilmavirta, Joonas

    2017-12-01

    We study ray transforms on spherically symmetric manifolds with a piecewise C1, 1 metric. Assuming the Herglotz condition, the x-ray transform is injective on the space of L 2 functions on such manifolds. We also prove injectivity results for broken ray transforms (with and without periodicity) on such manifolds with a C1, 1 metric. To make these problems tractable in low regularity, we introduce and study a class of generalized Abel transforms and study their properties. This low regularity setting is relevant for geophysical applications.

  4. 26 CFR 31.3121(c)-1 - Included and excluded services.

    Science.gov (United States)

    2010-04-01

    ...) EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT... enrolled and is regularly attending classes at a university, to perform domestic service for the club and...

  5. 2-(2-Pyridyl) Benzimidazole Analogs and their beta-Glucuronidase Inhibitory Activity

    International Nuclear Information System (INIS)

    Kamil, A.; Noureen, S.

    2015-01-01

    Synthesis of 2-(2-Pyridyl) benzimidazole analogs 1-11 have been carried out and evaluated for in vitro beta-glucuronidase inhibitory potential. The compounds 4 (IC/sub 50/ = 4.06 ± 0.34 meuM), 5 (IC/sub 50/ = 09.63 ± 0.81 meuM), 1 (IC/sub 50/ = 19.66 ± 0.44 meuM), 7 (IC/sub 50/ = 24.75 ± 0.25 meuM), 6 (IC/sub 50/ = 26.30 ± 1.37 meuM), and 3 (IC/sub 50/ = 32.11 ± 0.89 meuM), showed beta-glucuronidase inhibitory activity superior to the standard D-saccharic acid 1,4-lactone, with (IC/sub 50/ = 48.4 ± 1.25 meuM). Based on structure-activity relationship, we discover a new class of potent beta-glucuronidase inhibitors. (author)

  6. On the tail behavior of a class of multivariate conditionally heteroskedastic processes

    DEFF Research Database (Denmark)

    Pedersen, Rasmus Søndergaard; Wintenberger, Olivier

    2017-01-01

    Conditions for geometric ergodicity of multivariate autoregressive conditional heteroskedasticity (ARCH) processes, with the so-called BEKK (Baba, Engle, Kraft, and Kroner) parametrization, are considered. We show for a class of BEKK-ARCH processes that the invariant distribution is regularly...... varying. In order to account for the possibility of different tail indices of the marginals, we consider the notion of vector scaling regular variation (VSRV), closely related to non-standard regular variation. The characterization of the tail behavior of the processes is used for deriving the asymptotic...

  7. Body Composition, Neuromuscular Performance, and Mobility: Comparison Between Regularly Exercising and Inactive Older Women.

    Science.gov (United States)

    Rava, Anni; Pihlak, Anu; Ereline, Jaan; Gapeyeva, Helena; Kums, Tatjana; Purge, Priit; Jürimäe, Jaak; Pääsuke, Mati

    2017-01-01

    The purpose of this study was to evaluate the differences in body composition, neuromuscular performance, and mobility in healthy, regularly exercising and inactive older women, and examine the relationship between skeletal muscle indices and mobility. Overall, 32 healthy older women participated. They were divided into groups according to their physical activity history as regularly exercising (n = 22) and inactive (n = 10) women. Body composition, hand grip strength, leg extensor muscle strength, rapid force development, power output, and mobility indices were assessed. Regularly exercising women had lower fat mass and higher values for leg extensor muscle strength and muscle quality, and also for mobility. Leg extensor muscle strength and power output during vertical jumping and appendicular lean mass per unit of body mass were associated with mobility in healthy older women. It was concluded that long-term regular exercising may have beneficial effects on body composition and physical function in older women.

  8. Approximate Noether symmetries and collineations for regular perturbative Lagrangians

    Science.gov (United States)

    Paliathanasis, Andronikos; Jamal, Sameerah

    2018-01-01

    Regular perturbative Lagrangians that admit approximate Noether symmetries and approximate conservation laws are studied. Specifically, we investigate the connection between approximate Noether symmetries and collineations of the underlying manifold. In particular we determine the generic Noether symmetry conditions for the approximate point symmetries and we find that for a class of perturbed Lagrangians, Noether symmetries are related to the elements of the Homothetic algebra of the metric which is defined by the unperturbed Lagrangian. Moreover, we discuss how exact symmetries become approximate symmetries. Finally, some applications are presented.

  9. 40 CFR 82.19 - Apportionment of baseline consumption allowances for class II controlled substances.

    Science.gov (United States)

    2010-07-01

    ... allowances for class II controlled substances. 82.19 Section 82.19 Protection of Environment ENVIRONMENTAL... Consumption Controls § 82.19 Apportionment of baseline consumption allowances for class II controlled... Ineos Fluor Americas HCFC-22 2,546,305 Kivlan & Company HCFC-22 2,081,018 MDA Manufacturing HCFC-22 2...

  10. The class of n-entire operators

    International Nuclear Information System (INIS)

    Silva, Luis O; Toloza, Julio H

    2013-01-01

    We introduce a classification of simple, regular, closed symmetric operators with deficiency indices (1, 1) according to a geometric criterion that extends the classical notions of entire operators and entire operators in the generalized sense due to M G Krein. We show that these classes of operators have several distinctive properties, some of them related to the spectra of their canonical self-adjoint extensions. In particular, we provide necessary and sufficient conditions on the spectra of two canonical self-adjoint extensions of an operator for it to belong to one of our classes. Our discussion is based on some recent results in the theory of de Branges spaces. (paper)

  11. Hidden Advantages and Disadvantages of Social Class.

    Science.gov (United States)

    Goudeau, Sébastien; Croizet, Jean-Claude

    2017-02-01

    Three studies conducted among fifth and sixth graders examined how school contexts disrupt the achievement of working-class students by staging unfair comparison with their advantaged middle-class peers. In regular classrooms, differences in performance among students are usually showcased in a way that does not acknowledge the advantage (i.e., higher cultural capital) experienced by middle-class students, whose upbringing affords them more familiarity with the academic culture than their working-class peers have. Results of Study 1 revealed that rendering differences in performance visible in the classroom by having students raise their hands was enough to undermine the achievement of working-class students. In Studies 2 and 3, we manipulated students' familiarity with an arbitrary standard as a proxy for social class. Our results suggest that classroom settings that make differences in performance visible undermine the achievement of the students who are less familiar with academic culture. In Study 3, we showed that being aware of the advantage in familiarity with a task restores the performance of the students who have less familiarity with the task.

  12. Quantification of fetal heart rate regularity using symbolic dynamics

    Science.gov (United States)

    van Leeuwen, P.; Cysarz, D.; Lange, S.; Geue, D.; Groenemeyer, D.

    2007-03-01

    Fetal heart rate complexity was examined on the basis of RR interval time series obtained in the second and third trimester of pregnancy. In each fetal RR interval time series, short term beat-to-beat heart rate changes were coded in 8bit binary sequences. Redundancies of the 28 different binary patterns were reduced by two different procedures. The complexity of these sequences was quantified using the approximate entropy (ApEn), resulting in discrete ApEn values which were used for classifying the sequences into 17 pattern sets. Also, the sequences were grouped into 20 pattern classes with respect to identity after rotation or inversion of the binary value. There was a specific, nonuniform distribution of the sequences in the pattern sets and this differed from the distribution found in surrogate data. In the course of gestation, the number of sequences increased in seven pattern sets, decreased in four and remained unchanged in six. Sequences that occurred less often over time, both regular and irregular, were characterized by patterns reflecting frequent beat-to-beat reversals in heart rate. They were also predominant in the surrogate data, suggesting that these patterns are associated with stochastic heart beat trains. Sequences that occurred more frequently over time were relatively rare in the surrogate data. Some of these sequences had a high degree of regularity and corresponded to prolonged heart rate accelerations or decelerations which may be associated with directed fetal activity or movement or baroreflex activity. Application of the pattern classes revealed that those sequences with a high degree of irregularity correspond to heart rate patterns resulting from complex physiological activity such as fetal breathing movements. The results suggest that the development of the autonomic nervous system and the emergence of fetal behavioral states lead to increases in not only irregular but also regular heart rate patterns. Using symbolic dynamics to

  13. Regularization of the double period method for experimental data processing

    Science.gov (United States)

    Belov, A. A.; Kalitkin, N. N.

    2017-11-01

    In physical and technical applications, an important task is to process experimental curves measured with large errors. Such problems are solved by applying regularization methods, in which success depends on the mathematician's intuition. We propose an approximation based on the double period method developed for smooth nonperiodic functions. Tikhonov's stabilizer with a squared second derivative is used for regularization. As a result, the spurious oscillations are suppressed and the shape of an experimental curve is accurately represented. This approach offers a universal strategy for solving a broad class of problems. The method is illustrated by approximating cross sections of nuclear reactions important for controlled thermonuclear fusion. Tables recommended as reference data are obtained. These results are used to calculate the reaction rates, which are approximated in a way convenient for gasdynamic codes. These approximations are superior to previously known formulas in the covered temperature range and accuracy.

  14. An iterative method for Tikhonov regularization with a general linear regularization operator

    NARCIS (Netherlands)

    Hochstenbach, M.E.; Reichel, L.

    2010-01-01

    Tikhonov regularization is one of the most popular approaches to solve discrete ill-posed problems with error-contaminated data. A regularization operator and a suitable value of a regularization parameter have to be chosen. This paper describes an iterative method, based on Golub-Kahan

  15. On a class of strongly degenerate and singular linear elliptic equation

    International Nuclear Information System (INIS)

    Duong Minh Duc, D.M.; Le Dung.

    1992-11-01

    We consider a class of strongly degenerate linear elliptic equation. The boundedness and the Holder regularity of the weak solutions in the weighted Sobolev-Hardy spaces will be studied. (author). 9 refs

  16. Singular tachyon kinks from regular profiles

    International Nuclear Information System (INIS)

    Copeland, E.J.; Saffin, P.M.; Steer, D.A.

    2003-01-01

    We demonstrate how Sen's singular kink solution of the Born-Infeld tachyon action can be constructed by taking the appropriate limit of initially regular profiles. It is shown that the order in which different limits are taken plays an important role in determining whether or not such a solution is obtained for a wide class of potentials. Indeed, by introducing a small parameter into the action, we are able circumvent the results of a recent paper which derived two conditions on the asymptotic tachyon potential such that the singular kink could be recovered in the large amplitude limit of periodic solutions. We show that this is explained by the non-commuting nature of two limits, and that Sen's solution is recovered if the order of the limits is chosen appropriately

  17. New spinor fields classes and applications

    Science.gov (United States)

    da Rocha, Roldao

    2017-01-01

    After revisiting the well-known Lounesto classification of spinor fields, wherefrom the bilinear covariants are considered as the landmark beyond Wigner classification, relevant features of regular and singular spinor fields are presented. Hence, non-standard spinor fields are scrutinised, together with their associated dynamics, paving recently found applications in Physics. The case of the new classes of spinors on 7-manifolds is revisited to provide concrete examples.

  18. Regular Expression Pocket Reference

    CERN Document Server

    Stubblebine, Tony

    2007-01-01

    This handy little book offers programmers a complete overview of the syntax and semantics of regular expressions that are at the heart of every text-processing application. Ideal as a quick reference, Regular Expression Pocket Reference covers the regular expression APIs for Perl 5.8, Ruby (including some upcoming 1.9 features), Java, PHP, .NET and C#, Python, vi, JavaScript, and the PCRE regular expression libraries. This concise and easy-to-use reference puts a very powerful tool for manipulating text and data right at your fingertips. Composed of a mixture of symbols and text, regular exp

  19. Regular Topographic Patterning of Karst Depressions Suggests Landscape Self-Organization

    Science.gov (United States)

    Quintero, C.; Cohen, M. J.

    2017-12-01

    Thousands of wetland depressions that are commonly host to cypress domes dot the sub-tropical limestone landscape of South Florida. The origin of these depression features has been the topic of debate. Here we build upon the work of previous surveyors of this landscape to analyze the morphology and spatial distribution of depressions on the Big Cypress landscape. We took advantage of the emergence and availability of high resolution Light Direction and Ranging (LiDAR) technology and ArcMap GIS software to analyze the structure and regularity of landscape features with methods unavailable to past surveyors. Six 2.25 km2 LiDAR plots within the preserve were selected for remote analysis and one depression feature within each plot was selected for more intensive sediment and water depth surveying. Depression features on the Big Cypress landscape were found to show strong evidence of regular spatial patterning. Periodicity, a feature of regularly patterned landscapes, is apparent in both Variograms and Radial Spectrum Analyses. Size class distributions of the identified features indicate constrained feature sizes while Average Nearest Neighbor analyses support the inference of dispersed features with non-random spacing. The presence of regular patterning on this landscape strongly implies biotic reinforcement of spatial structure by way of the scale dependent feedback. In characterizing the structure of this wetland landscape we add to the growing body of work dedicated to documenting how water, life and geology may interact to shape the natural landscapes we see today.

  20. Perceived psychological pressure at work, social class, and risk of stroke: a 30-year follow-up in Copenhagen male study.

    Science.gov (United States)

    Suadicani, Poul; Andersen, Lars L; Holtermann, Andreas; Mortensen, Ole S; Gyntelberg, Finn

    2011-12-01

    Investigate if the association between perceived psychological work pressure and risk of stroke is modified by socioeconomic status. Thirty-year follow-up of 4943 middle-aged men without cardiovascular disease. In the higher social classes (I, II, and III), perceived regular exposure to psychological work pressure was common and a significant predictor of stroke; almost 10% of the stroke events could be attributed to this exposure in the higher social classes; among lower social classes (IV and V), perceived psychological pressure was no predictor at all. Regular psychological work pressure is a highly prevalent and independent risk factor for stroke among men in higher social classes. In contrast, no association to stroke risk was found among low social class men.

  1. SU-E-T-172: Evaluation of the Exradin A26 Ion Chamber in Megavoltage Photon Beams as a Reference Class Instrument

    International Nuclear Information System (INIS)

    McEwen, M

    2014-01-01

    Purpose: The Exradin A26 is a new design of micro-ionization ion chamber that externally resembles the Exradin A16 model but has significant internal changes to address measurement issues reported in the literature for the A16. This project involved the characterization of two versions of the A26 chamber in high energy x-rays with particular reference to the performance specification laid out in the imminent Addendum to TG-51. Methods: The Exradin A26 was investigated in a range of megavoltage photon beams (6–25 MV). Investigations looked at chamber settling, ion recombination and polarity. Since it has been previously shown that non-ideal performance is most easily identified through ion recombination measurements, the focus was on the determination of Pion. Results: i) Chamber settling - the chamber response stabilizes very quickly (within 3 minutes), even after a large change in the polarizing voltage.ii) The polarity correction was found to be small (within 0.2% of unity)iii) The chamber showed linear behavior for a Jaffe plot (1/reading vs 1/polarizing voltage) for applied voltages ≤ 200 V.iv) The recombination correction showed a linear variation with the doseper- pulse, was not significantly dependent on the polarity of the collecting voltage and was consistent with the chamber dimensions (i.e. agreed with Boag theory). Conclusion: An initial investigation of the Exradin A26 micro chamber suggests that although its performance exceeds the AAPM specification for a reference-class ion chamber for use in megavoltage photon beams it is a significant improvement over the previous A16 design. Further work is required to evaluate long-term stability and determine kQ factors

  2. 26 CFR 301.6323(i)-1 - Special rules.

    Science.gov (United States)

    2010-04-01

    ... organization to communicate information unless such communication is part of his regular duties or unless he... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Special rules. 301.6323(i)-1 Section 301.6323(i)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURE AND...

  3. On convergence rates for iteratively regularized procedures with linear penalty terms

    International Nuclear Information System (INIS)

    Smirnova, Alexandra

    2012-01-01

    The impact of this paper is twofold. First, we study convergence rates of the iteratively regularized Gauss–Newton (IRGN) algorithm with a linear penalty term under a generalized source assumption and show how the regularizing properties of new iterations depend on the solution smoothness. Secondly, we introduce an adaptive IRGN procedure, which is investigated under a relaxed smoothness condition. The introduction and analysis of a more general penalty term are of great importance since, apart from bringing stability to the numerical scheme designed for solving a large class of applied inverse problems, it allows us to incorporate various types of a priori information available on the model. Both a priori and a posteriori stopping rules are investigated. For the a priori stopping rule, optimal convergence rates are derived. A numerical example illustrating convergence rates is considered. (paper)

  4. The Jump Set under Geometric Regularization. Part 1: Basic Technique and First-Order Denoising

    KAUST Repository

    Valkonen, Tuomo

    2015-01-01

    © 2015 Society for Industrial and Applied Mathematics. Let u ∈ BV(Ω) solve the total variation (TV) denoising problem with L2-squared fidelity and data f. Caselles, Chambolle, and Novaga [Multiscale Model. Simul., 6 (2008), pp. 879-894] have shown the containment Hm-1 (Ju \\\\Jf) = 0 of the jump set Ju of u in that of f. Their proof unfortunately depends heavily on the co-area formula, as do many results in this area, and as such is not directly extensible to higher-order, curvature-based, and other advanced geometric regularizers, such as total generalized variation and Euler\\'s elastica. These have received increased attention in recent times due to their better practical regularization properties compared to conventional TV or wavelets. We prove analogous jump set containment properties for a general class of regularizers. We do this with novel Lipschitz transformation techniques and do not require the co-area formula. In the present Part 1 we demonstrate the general technique on first-order regularizers, while in Part 2 we will extend it to higher-order regularizers. In particular, we concentrate in this part on TV and, as a novelty, Huber-regularized TV. We also demonstrate that the technique would apply to nonconvex TV models as well as the Perona-Malik anisotropic diffusion, if these approaches were well-posed to begin with.

  5. Identifying classes of persons with mild intellectual disability or borderline intellectual functioning: a latent class analysis.

    Science.gov (United States)

    Nouwens, Peter J G; Lucas, Rosanne; Smulders, Nienke B M; Embregts, Petri J C M; van Nieuwenhuizen, Chijs

    2017-07-17

    Persons with mild intellectual disability or borderline intellectual functioning are often studied as a single group with similar characteristics. However, there are indications that differences exist within this population. Therefore, the aim of this study was to identify classes of persons with mild intellectual disability or borderline intellectual functioning and to examine whether these classes are related to individual and/or environmental characteristics. Latent class analysis was performed using file data of 250 eligible participants with a mean age of 26.1 (SD 13.8, range 3-70) years. Five distinct classes of persons with mild intellectual disability or borderline intellectual functioning were found. These classes significantly differed in individual and environmental characteristics. For example, persons with a mild intellectual disability experienced fewer problems than those with borderline intellectual disability. The identification of five classes implies that a differentiated approach is required towards persons with mild intellectual disability or borderline intellectual functioning.

  6. Social Participation and Friendship Quality of Students with Special Educational Needs in Regular Greek Primary Schools

    Science.gov (United States)

    Avramidis, Elias; Avgeri, Georgia; Strogilos, Vasilis

    2018-01-01

    The study addresses the social participation of integrated students with special educational needs (SEN) in upper primary regular classes in Greece alongside their perceptions of best friend quality. Social participation was defined as consisting of four key dimensions: students' acceptance by classmates, friendships, social self-perceptions, and…

  7. 2-regularity and 2-normality conditions for systems with impulsive controls

    Directory of Open Access Journals (Sweden)

    Pavlova Natal'ya

    2007-01-01

    Full Text Available In this paper a controlled system with impulsive controls in the neighborhood of an abnormal point is investigated. The set of pairs (u,μ is considered as a class of admissible controls, where u is a measurable essentially bounded function and μ is a finite-dimensional Borel measure, such that for any Borel set B, μ(B is a subset of the given convex closed pointed cone. In this article the concepts of 2-regularity and 2-normality for the abstract mapping Ф, operating from the given Banach space into a finite-dimensional space, are introduced. The concepts of 2-regularity and 2-normality play a great role in the course of derivation of the first and the second order necessary conditions for the optimal control problem, consisting of the minimization of a certain functional on the set of the admissible processes. These concepts are also important for obtaining the sufficient conditions for the local controllability of the nonlinear systems. The convenient criterion for 2-regularity along the prescribed direction and necessary conditions for 2-normality of systems, linear in control, are introduced in this article as well.

  8. Gene transfer preferentially selects MHC class I positive tumour cells and enhances tumour immunogenicity.

    Science.gov (United States)

    Hacker, Ulrich T; Schildhauer, Ines; Barroso, Margarita Céspedes; Kofler, David M; Gerner, Franz M; Mysliwietz, Josef; Buening, Hildegard; Hallek, Michael; King, Susan B S

    2006-05-01

    The modulated expression of MHC class I on tumour tissue is well documented. Although the effect of MHC class I expression on the tumorigenicity and immunogenicity of MHC class I negative tumour cell lines has been rigorously studied, less is known about the validity of gene transfer and selection in cell lines with a mixed MHC class I phenotype. To address this issue we identified a C26 cell subline that consists of distinct populations of MHC class I (H-2D/K) positive and negative cells. Transient transfection experiments using liposome-based transfer showed a lower transgene expression in MHC class I negative cells. In addition, MHC class I negative cells were more sensitive to antibiotic selection. This led to the generation of fully MHC class I positive cell lines. In contrast to C26 cells, all transfectants were rejected in vivo and induced protection against the parental tumour cells in rechallenge experiments. Tumour cell specificity of the immune response was demonstrated in in vitro cytokine secretion and cytotoxicity assays. Transfectants expressing CD40 ligand and hygromycin phosphotransferase were not more immunogenic than cells expressing hygromycin resistance alone. We suggest that the MHC class I positive phenotype of the C26 transfectants had a bearing on their immunogenicity, because selected MHC class I positive cells were more immunogenic than parental C26 cells and could induce specific anti-tumour immune responses. These data demonstrate that the generation of tumour cell transfectants can lead to the selection of subpopulations that show an altered phenotype compared to the parental cell line and display altered immunogenicity independent of selection marker genes or other immune modulatory genes. Our results show the importance of monitoring gene transfer in the whole tumour cell population, especially for the evaluation of in vivo therapies targeted to heterogeneous tumour cell populations.

  9. The geometry of continuum regularization

    International Nuclear Information System (INIS)

    Halpern, M.B.

    1987-03-01

    This lecture is primarily an introduction to coordinate-invariant regularization, a recent advance in the continuum regularization program. In this context, the program is seen as fundamentally geometric, with all regularization contained in regularized DeWitt superstructures on field deformations

  10. Regular expression containment

    DEFF Research Database (Denmark)

    Henglein, Fritz; Nielsen, Lasse

    2011-01-01

    We present a new sound and complete axiomatization of regular expression containment. It consists of the conventional axiomatiza- tion of concatenation, alternation, empty set and (the singleton set containing) the empty string as an idempotent semiring, the fixed- point rule E* = 1 + E × E......* for Kleene-star, and a general coin- duction rule as the only additional rule. Our axiomatization gives rise to a natural computational inter- pretation of regular expressions as simple types that represent parse trees, and of containment proofs as coercions. This gives the axiom- atization a Curry......-Howard-style constructive interpretation: Con- tainment proofs do not only certify a language-theoretic contain- ment, but, under our computational interpretation, constructively transform a membership proof of a string in one regular expres- sion into a membership proof of the same string in another regular expression. We...

  11. Supersymmetric dimensional regularization

    International Nuclear Information System (INIS)

    Siegel, W.; Townsend, P.K.; van Nieuwenhuizen, P.

    1980-01-01

    There is a simple modification of dimension regularization which preserves supersymmetry: dimensional reduction to real D < 4, followed by analytic continuation to complex D. In terms of component fields, this means fixing the ranges of all indices on the fields (and therefore the numbers of Fermi and Bose components). For superfields, it means continuing in the dimensionality of x-space while fixing the dimensionality of theta-space. This regularization procedure allows the simple manipulation of spinor derivatives in supergraph calculations. The resulting rules are: (1) First do all algebra exactly as in D = 4; (2) Then do the momentum integrals as in ordinary dimensional regularization. This regularization procedure needs extra rules before one can say that it is consistent. Such extra rules needed for superconformal anomalies are discussed. Problems associated with renormalizability and higher order loops are also discussed

  12. Centralizers of maximal regular subgroups in simple Lie groups and relative congruence classes of representations

    Energy Technology Data Exchange (ETDEWEB)

    Larouche, M [Departement de Mathematiques et Statistique, Universite de Montreal, 2920 chemin de la Tour, Montreal, Quebec H3T 1J4 (Canada); Lemire, F W [Department of Mathematics, University of Windsor, Windsor, Ontario (Canada); Patera, J, E-mail: larouche@dms.umontreal.ca, E-mail: lemire@uwindsor.ca, E-mail: patera@crm.umontreal.ca [Centre de Recherches Mathematiques, Universite de Montreal, CP 6128-Centre ville, Montreal, Quebec H3C 3J7 (Canada)

    2011-10-14

    In this paper, we present a new, uniform and comprehensive description of centralizers of the maximal regular subgroups in compact simple Lie groups of all types and ranks. The centralizer is either a direct product of finite cyclic groups, a continuous group of rank 1, or a product, not necessarily direct, of a continuous group of rank 1 with a finite cyclic group. Explicit formulas for the action of such centralizers on irreducible representations of the simple Lie algebras are given. (paper)

  13. Efficient rare-event simulation for multiple jump events in regularly varying random walks and compound Poisson processes

    NARCIS (Netherlands)

    B. Chen (Bohan); J. Blanchet; C.H. Rhee (Chang-Han); A.P. Zwart (Bert)

    2017-01-01

    textabstractWe propose a class of strongly efficient rare event simulation estimators for random walks and compound Poisson processes with a regularly varying increment/jump-size distribution in a general large deviations regime. Our estimator is based on an importance sampling strategy that hinges

  14. Regularization by External Variables

    DEFF Research Database (Denmark)

    Bossolini, Elena; Edwards, R.; Glendinning, P. A.

    2016-01-01

    Regularization was a big topic at the 2016 CRM Intensive Research Program on Advances in Nonsmooth Dynamics. There are many open questions concerning well known kinds of regularization (e.g., by smoothing or hysteresis). Here, we propose a framework for an alternative and important kind of regula......Regularization was a big topic at the 2016 CRM Intensive Research Program on Advances in Nonsmooth Dynamics. There are many open questions concerning well known kinds of regularization (e.g., by smoothing or hysteresis). Here, we propose a framework for an alternative and important kind...

  15. 1 / n Expansion for the Number of Matchings on Regular Graphs and Monomer-Dimer Entropy

    Science.gov (United States)

    Pernici, Mario

    2017-08-01

    Using a 1 / n expansion, that is an expansion in descending powers of n, for the number of matchings in regular graphs with 2 n vertices, we study the monomer-dimer entropy for two classes of graphs. We study the difference between the extensive monomer-dimer entropy of a random r-regular graph G (bipartite or not) with 2 n vertices and the average extensive entropy of r-regular graphs with 2 n vertices, in the limit n → ∞. We find a series expansion for it in the numbers of cycles; with probability 1 it converges for dimer density p diverges as |ln(1-p)| for p → 1. In the case of regular lattices, we similarly expand the difference between the specific monomer-dimer entropy on a lattice and the one on the Bethe lattice; we write down its Taylor expansion in powers of p through the order 10, expressed in terms of the number of totally reducible walks which are not tree-like. We prove through order 6 that its expansion coefficients in powers of p are non-negative.

  16. Prevalence and Correlates of Having a Regular Physician among Women Presenting for Induced Abortion.

    Science.gov (United States)

    Chor, Julie; Hebert, Luciana E; Hasselbacher, Lee A; Whitaker, Amy K

    2016-01-01

    To determine the prevalence and correlates of having a regular physician among women presenting for induced abortion. We conducted a retrospective review of women presenting to an urban, university-based family planning clinic for abortion between January 2008 and September 2011. We conducted bivariate analyses, comparing women with and without a regular physician, and multivariable regression modeling, to identify factors associated with not having a regular physician. Of 834 women, 521 (62.5%) had a regular physician and 313 (37.5%) did not. Women with a prior pregnancy, live birth, or spontaneous abortion were more likely than women without these experiences to have a regular physician. Women with a prior induced abortion were not more likely than women who had never had a prior induced abortion to have a regular physician. Compared with women younger than 18 years, women aged 18 to 26 years were less likely to have a physician (adjusted odds ratio [aOR], 0.25; 95% confidence interval [CI], 0.10-0.62). Women with a prior live birth had increased odds of having a regular physician compared with women without a prior pregnancy (aOR, 1.89; 95% CI, 1.13-3.16). Women without medical/fetal indications and who had not been victims of sexual assault (self-indicated) were less likely to report having a regular physician compared with women with medical/fetal indications (aOR, 0.55; 95% CI, 0.17-0.82). The abortion visit is a point of contact with a large number of women without a regular physician and therefore provides an opportunity to integrate women into health care. Copyright © 2016 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.

  17. Regular Single Valued Neutrosophic Hypergraphs

    Directory of Open Access Journals (Sweden)

    Muhammad Aslam Malik

    2016-12-01

    Full Text Available In this paper, we define the regular and totally regular single valued neutrosophic hypergraphs, and discuss the order and size along with properties of regular and totally regular single valued neutrosophic hypergraphs. We also extend work on completeness of single valued neutrosophic hypergraphs.

  18. Patterns of cannabis use during adolescence and their association with harmful substance use behaviour: findings from a UK birth cohort.

    Science.gov (United States)

    Taylor, Michelle; Collin, Simon M; Munafò, Marcus R; MacLeod, John; Hickman, Matthew; Heron, Jon

    2017-08-01

    Evidence on the role of cannabis as a gateway drug is inconsistent. We characterise patterns of cannabis use among UK teenagers aged 13-18 years, and assess their influence on problematic substance use at age 21 years. We used longitudinal latent class analysis to derive trajectories of cannabis use from self-report measures in a UK birth cohort. We investigated (1) factors associated with latent class membership and (2) whether latent class membership predicted subsequent nicotine dependence, harmful alcohol use and recent use of other illicit drugs at age 21 years. 5315 adolescents had three or more measures of cannabis use from age 13 to 18 years. Cannabis use patterns were captured as four latent classes corresponding to 'non-users' (80.1%), 'late-onset occasional' (14.2%), 'early-onset occasional' (2.3%) and 'regular' users (3.4%). Sex, mother's substance use, and child's tobacco use, alcohol consumption and conduct problems were strongly associated with cannabis use. At age 21 years, compared with the non-user class, late-onset occasional, early-onset occasional and regular cannabis user classes had higher odds of nicotine dependence (OR=3.5, 95% CI 0.7 to 17.9; OR=12.1, 95% CI 1.0 to 150.3; and OR=37.2, 95% CI 9.5 to 144.8, respectively); harmful alcohol consumption (OR=2.6, 95% CI 1.5 to 4.3; OR=5.0, 95% CI 2.1 to 12.1; and OR=2.6, 95% CI 1.0 to 7.1, respectively); and other illicit drug use (OR=22.7, 95% CI 11.3 to 45.7; OR=15.9, 95% CI 3.9 to 64.4; and OR=47.9, 95% CI 47.9 to 337.0, respectively). One-fifth of the adolescents in our sample followed a pattern of occasional or regular cannabis use, and these young people were more likely to progress to harmful substance use behaviours in early adulthood. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  19. 26 CFR 1.1296-2 - Definition of marketable stock.

    Science.gov (United States)

    2010-04-01

    ... means— (1) Passive foreign investment company (PFIC) stock that is regularly traded, as defined in... section, a class of stock that is traded on one or more qualified exchanges or other markets, as defined... (B) The rules of the exchange effectively promote active trading of listed stocks. (2) Exchange with...

  20. On a correspondence between regular and non-regular operator monotone functions

    DEFF Research Database (Denmark)

    Gibilisco, P.; Hansen, Frank; Isola, T.

    2009-01-01

    We prove the existence of a bijection between the regular and the non-regular operator monotone functions satisfying a certain functional equation. As an application we give a new proof of the operator monotonicity of certain functions related to the Wigner-Yanase-Dyson skew information....

  1. 78 FR 18800 - Amendment of Class E Airspace; Decorah, IA

    Science.gov (United States)

    2013-03-28

    ...-1433; Airspace Docket No. 11-ACE-26] Amendment of Class E Airspace; Decorah, IA AGENCY: Federal... Decorah, IA. Decommissioning of the Decorah non-directional beacon (NDB) at Decorah Municipal Airport has... Register a notice of proposed rulemaking (NPRM) to amend Class E airspace for the Decorah, IA, area...

  2. Stochastic analytic regularization

    International Nuclear Information System (INIS)

    Alfaro, J.

    1984-07-01

    Stochastic regularization is reexamined, pointing out a restriction on its use due to a new type of divergence which is not present in the unregulated theory. Furthermore, we introduce a new form of stochastic regularization which permits the use of a minimal subtraction scheme to define the renormalized Green functions. (author)

  3. Effects of regularly consuming dietary fibre rich soluble cocoa products on bowel habits in healthy subjects: a free-living, two-stage, randomized, crossover, single-blind intervention

    Directory of Open Access Journals (Sweden)

    Sarriá Beatriz

    2012-04-01

    Full Text Available Abstract Background Dietary fibre is both preventive and therapeutic for bowel functional diseases. Soluble cocoa products are good sources of dietary fibre that may be supplemented with this dietary component. This study assessed the effects of regularly consuming two soluble cocoa products (A and B with different non-starch polysaccharides levels (NSP, 15.1 and 22.0% w/w, respectively on bowel habits using subjective intestinal function and symptom questionnaires, a daily diary and a faecal marker in healthy individuals. Methods A free-living, two-stage, randomized, crossover, single-blind intervention was carried out in 44 healthy men and women, between 18-55 y old, who had not taken dietary supplements, laxatives, or antibiotics six months before the start of the study. In the four-week-long intervention stages, separated by a three-week-wash-out stage, two servings of A and B, that provided 2.26 vs. 6.60 g/day of NSP respectively, were taken. In each stage, volunteers' diet was recorded using a 72-h food intake report. Results Regularly consuming cocoa A and B increased fibre intake, although only cocoa B significantly increased fibre intake (p Conclusions Regular consumption of the cocoa products increases dietary fibre intake to recommended levels and product B improves bowel habits. The use of both objective and subjective assessments to evaluate the effects of food on bowel habits is recommended.

  4. 77 FR 49720 - Establishment of Class E Airspace; Chenega Bay, AK

    Science.gov (United States)

    2012-08-17

    ...). The NBAA recommended that the FAA lower some of the adjacent Class E airspace down to 1,200 feet above...-1429; Airspace Docket No. 11-AAL-22] Establishment of Class E Airspace; Chenega Bay, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E airspace...

  5. Decoding Skills Acquired by Low Readers Taught in Regular Classrooms Using Clinical Techniques. Research Report No. 35.

    Science.gov (United States)

    Gallistel, Elizabeth; Fischer, Phyllis

    This study evaluated the decoding skills acquired by low readers in an experimental project that taught low readers in regular class through the use of clinical procedures based on a synthetic phonic, multisensory approach. An evaluation instrument which permitted the tabulation of specific decoding skills was administered as a pretest and…

  6. 77 FR 71362 - Proposed Amendment of Class E Airspace; Decorah, IA

    Science.gov (United States)

    2012-11-30

    ...-1433; Airspace Docket No. 11-ACE-26] Proposed Amendment of Class E Airspace; Decorah, IA AGENCY... action proposes to amend Class E airspace at Decorah, IA. Decommissioning of the Decorah non-directional... instrument approach procedures at Decorah Municipal Airport, Decorah, IA. Airspace reconfiguration is...

  7. The impact of the inclusion of students with handicaps and disabilities in the regular education science classroom

    Science.gov (United States)

    Donald, Cathey Nolan

    This study was conducted to determine the impact of the inclusion of students with handicaps and disabilities in the regular education science classroom. Surveys were mailed to the members of the Alabama Science Teachers Association to obtain information from teachers in inclusive classrooms. Survey responses from teachers provide insight into these classrooms. This study reports the results of the teachers surveyed. Results indicate multiple changes occur in the educational opportunities presented to regular education students when students with handicaps and disabilities are included in the regular science classroom. Responding teachers (60%) report omitting activities that formerly provided experiences for students, such as laboratory activities using dangerous materials, field activities, and some group activities. Also omitted, in many instances (64.1%), are skill building opportunities of word problems and higher order thinking skills. Regular education students participate in classes where discipline problems related to included students are reported as the teachers most time consuming task. In these classrooms, directions are repeated frequently, reteaching of material already taught occurs, and the pace of instruction has been slowed. These changes to the regular classroom occur across school levels. Many teachers (44.9%) report they do not see benefits associated with the inclusion of students with special needs in the regular classroom.

  8. New class of inhomogeneous cosmological perfect-fluid solutions without big-bang singularity

    Energy Technology Data Exchange (ETDEWEB)

    Senovilla, J.M.M. (Grupo de Fisica Teorica, Departamento de Fisica, Ingenieria y Radiologia Medica, Facultad de Ciencias, Universidad de Salamanca, 37008 Salmanaca (Spain))

    1990-05-07

    A new class of exact solutions to Einstein's field equations with a perfect-fluid source is presented. The solutions describe spatially inhomogeneous cosmological models and have a realistic equation of state {ital p}={rho}/3. The properties of the solutions are discussed. The most remarkable feature is the absence of an initial singularity, the curvature and matter invariants being regular and smooth everywhere. We also present an alternative interpretation of the solution as a globally regular cylindrically symmetric space-time.

  9. Expanding the boundaries of evaluative learning research: How intersecting regularities shape our likes and dislikes.

    Science.gov (United States)

    Hughes, Sean; De Houwer, Jan; Perugini, Marco

    2016-06-01

    Over the last 30 years, researchers have identified several types of procedures through which novel preferences may be formed and existing ones altered. For instance, regularities in the presence of a single stimulus (as in the case of mere exposure) or 2 or more stimuli (as in the case of evaluative conditioning) have been shown to influence liking. We propose that intersections between regularities represent a previously unrecognized class of procedures for changing liking. Across 4 related studies, we found strong support for the hypothesis that when environmental regularities intersect with one another (i.e., share elements or have elements that share relations with other elements), the evaluative properties of the elements of those regularities can change. These changes in liking were observed across a range of stimuli and procedures and were evident when self-report measures, implicit measures, and behavioral choice measures of liking were employed. Functional and mental explanations of this phenomenon are offered followed by a discussion of how this new type of evaluative learning effect can accelerate theoretical, methodological, and empirical development in attitude research. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  10. Special Education Reform Towards Inclusive Education: Blurring or Expanding Boundaries of Special and Regular Education in China

    Science.gov (United States)

    Deng, Meng; Zhu, Xinhua

    2016-01-01

    China has developed a three-tier special education service delivery system consisting of an array of placement options of special schools, special classes and learning in regular classrooms (LRC) (with the LRC as the major initiative) to serve students with disabilities after 1980s responding to the international trend of inclusive education…

  11. Effective field theory dimensional regularization

    International Nuclear Information System (INIS)

    Lehmann, Dirk; Prezeau, Gary

    2002-01-01

    A Lorentz-covariant regularization scheme for effective field theories with an arbitrary number of propagating heavy and light particles is given. This regularization scheme leaves the low-energy analytic structure of Greens functions intact and preserves all the symmetries of the underlying Lagrangian. The power divergences of regularized loop integrals are controlled by the low-energy kinematic variables. Simple diagrammatic rules are derived for the regularization of arbitrary one-loop graphs and the generalization to higher loops is discussed

  12. Effective field theory dimensional regularization

    Science.gov (United States)

    Lehmann, Dirk; Prézeau, Gary

    2002-01-01

    A Lorentz-covariant regularization scheme for effective field theories with an arbitrary number of propagating heavy and light particles is given. This regularization scheme leaves the low-energy analytic structure of Greens functions intact and preserves all the symmetries of the underlying Lagrangian. The power divergences of regularized loop integrals are controlled by the low-energy kinematic variables. Simple diagrammatic rules are derived for the regularization of arbitrary one-loop graphs and the generalization to higher loops is discussed.

  13. Discriminative Elastic-Net Regularized Linear Regression.

    Science.gov (United States)

    Zhang, Zheng; Lai, Zhihui; Xu, Yong; Shao, Ling; Wu, Jian; Xie, Guo-Sen

    2017-03-01

    In this paper, we aim at learning compact and discriminative linear regression models. Linear regression has been widely used in different problems. However, most of the existing linear regression methods exploit the conventional zero-one matrix as the regression targets, which greatly narrows the flexibility of the regression model. Another major limitation of these methods is that the learned projection matrix fails to precisely project the image features to the target space due to their weak discriminative capability. To this end, we present an elastic-net regularized linear regression (ENLR) framework, and develop two robust linear regression models which possess the following special characteristics. First, our methods exploit two particular strategies to enlarge the margins of different classes by relaxing the strict binary targets into a more feasible variable matrix. Second, a robust elastic-net regularization of singular values is introduced to enhance the compactness and effectiveness of the learned projection matrix. Third, the resulting optimization problem of ENLR has a closed-form solution in each iteration, which can be solved efficiently. Finally, rather than directly exploiting the projection matrix for recognition, our methods employ the transformed features as the new discriminate representations to make final image classification. Compared with the traditional linear regression model and some of its variants, our method is much more accurate in image classification. Extensive experiments conducted on publicly available data sets well demonstrate that the proposed framework can outperform the state-of-the-art methods. The MATLAB codes of our methods can be available at http://www.yongxu.org/lunwen.html.

  14. Flowchart Programs, Regular Expressions, and Decidability of Polynomial Growth-Rate

    Directory of Open Access Journals (Sweden)

    Amir M. Ben-Amram

    2016-07-01

    Full Text Available We present a new method for inferring complexity properties for a class of programs in the form of flowcharts annotated with loop information. Specifically, our method can (soundly and completely decide if computed values are polynomially bounded as a function of the input; and similarly for the running time. Such complexity properties are undecidable for a Turing-complete programming language, and a common work-around in program analysis is to settle for sound but incomplete solutions. In contrast, we consider a class of programs that is Turing-incomplete, but strong enough to include several challenges for this kind of analysis. For a related language that has well-structured syntax, similar to Meyer and Ritchie's LOOP programs, the problem has been previously proved to be decidable. The analysis relied on the compositionality of programs, hence the challenge in obtaining similar results for flowchart programs with arbitrary control-flow graphs. Our answer to the challenge is twofold: first, we propose a class of loop-annotated flowcharts, which is more general than the class of flowcharts that directly represent structured programs; secondly, we present a technique to reuse the ideas from the work on tructured programs and apply them to such flowcharts. The technique is inspired by the classic translation of non-deterministic automata to regular expressions, but we obviate the exponential cost of constructing such an expression, obtaining a polynomial-time analysis. These ideas may well be applicable to other analysis problems.

  15. Consumo regular de frutas e hortaliças por estudantes universitários em Rio Branco, Acre, Brasil: prevalência e fatores associados Regular consumption of fruits and vegetables by university students in Rio Branco, Acre State, Brazil: prevalence and associated factors

    Directory of Open Access Journals (Sweden)

    Alanderson Alves Ramalho

    2012-07-01

    Full Text Available Estudo transversal com universitários realizado para analisar a prevalência e os fatores associados ao consumo regular de frutas e hortaliças por acadêmicos de uma universidade pública federal de Rio Branco, Acre, Brasil. Foram investigados 863 estudantes de cursos de graduação em 2010. A prevalência geral de consumo regular de frutas e hortaliças foi de 14,8%. Os fatores associados ao consumo regular de frutas e hortaliças foram: pertencer à classe econômica A/B (RP = 1,70; IC95%: 1,10-2,62, conviver com companheiro(a (RP = 1,53; IC95%: 1,02-2,29, praticar atividade física (RP = 1,69; IC95%: 1,11-2,56 e consumo de fast food igual ou menor que 2 vezes na semana (RP = 1,49; IC95%: 1,04-2,13. Em conclusão, destaca-se que a minoria dos acadêmicos alcançou a recomendação de consumir frutas e hortaliças em 5 dias ou mais da semana. O consumo regular desses alimentos mostrou-se associado aos aspectos socioeconômicos e aos hábitos saudáveis relacionados à prática de atividade física e baixo consumo de fast food.This cross-sectional study with university students examined the prevalence of regular consumption of fruits and vegetables and associated factors among students at a Federal university in Rio Branco, Acre State, Brazil. 863 undergraduates were interviewed in 2010. Overall prevalence of regular consumption of fruits and vegetables was 14.8%. Factors associated with regular consumption of fruits and vegetables were: socioeconomic classes A and B (PR = 1.70; 95%CI: 1.10-2.62, living with a partner (PR = 1.53; 95%CI: 1.02-2.29, regular physical activity (PR = 1.69; 95%CI: 1.11-2.56, and consumption of fast food twice a week or less (PR = 1.49; 95%CI: 1.04-2.13. A minority of the students met the recommendation to consume fruits and vegetables 5 or more days a week. Regular fruit and vegetable consumption was associated with socioeconomic status and healthy habits such as physical exercise and low consumption of fast food.

  16. Hierarchical regular small-world networks

    International Nuclear Information System (INIS)

    Boettcher, Stefan; Goncalves, Bruno; Guclu, Hasan

    2008-01-01

    Two new networks are introduced that resemble small-world properties. These networks are recursively constructed but retain a fixed, regular degree. They possess a unique one-dimensional lattice backbone overlaid by a hierarchical sequence of long-distance links, mixing real-space and small-world features. Both networks, one 3-regular and the other 4-regular, lead to distinct behaviors, as revealed by renormalization group studies. The 3-regular network is planar, has a diameter growing as √N with system size N, and leads to super-diffusion with an exact, anomalous exponent d w = 1.306..., but possesses only a trivial fixed point T c = 0 for the Ising ferromagnet. In turn, the 4-regular network is non-planar, has a diameter growing as ∼2 √(log 2 N 2 ) , exhibits 'ballistic' diffusion (d w = 1), and a non-trivial ferromagnetic transition, T c > 0. It suggests that the 3-regular network is still quite 'geometric', while the 4-regular network qualifies as a true small world with mean-field properties. As an engineering application we discuss synchronization of processors on these networks. (fast track communication)

  17. 75 FR 76006 - Regular Meeting

    Science.gov (United States)

    2010-12-07

    ... FARM CREDIT SYSTEM INSURANCE CORPORATION Regular Meeting AGENCY: Farm Credit System Insurance Corporation Board. ACTION: Regular meeting. SUMMARY: Notice is hereby given of the regular meeting of the Farm Credit System Insurance Corporation Board (Board). Date and Time: The meeting of the Board will be held...

  18. Leisure time physical activity in a 22-year follow-up among Finnish adults.

    Science.gov (United States)

    Borodulin, Katja; Mäkinen, Tomi E; Leino-Arjas, Päivi; Tammelin, Tuija H; Heliövaara, Markku; Martelin, Tuija; Kestilä, Laura; Prättälä, Ritva

    2012-10-02

    The aim of this study was to explore long-term predictors of leisure time physical activity in the general population. This study comprised 718 men and women who participated in the national Mini-Finland Health Survey from 1978-1980 and were re-examined in 2001. Participants were aged 30-80 at baseline. Measurements included interviews, health examinations, and self-administered questionnaires, with information on socioeconomic position, occupational and leisure time physical activity, physical fitness, body mass index, smoking, alcohol consumption, and physical functional capacity. Analyses included persons who were working and had no limitations in functional capacity at baseline. The strongest predictor of being physically active at the follow-up was participation in physical activity at baseline, with an OR 13.82 (95%CI 5.50-34.70) for 3 or more types of regular activity, OR 2.33 (95%CI 1.22-4.47) for 1-2 types of regular activity, and OR 3.26 (95%CI 2.07-5.15) for irregular activity, as compared to no activity. Other determinants for being physically active were moving upwards in occupational status, a high level of baseline occupational physical activity and remaining healthy weight during the follow-up. To prevent physical inactivity among older adults, it is important to promote physical activity already in young adulthood and in middle age and to emphasize the importance of participating in many types of physical activity.

  19. 19 CFR 122.26 - Entry and clearance.

    Science.gov (United States)

    2010-04-01

    ... AIR COMMERCE REGULATIONS Private Aircraft § 122.26 Entry and clearance. Private aircraft, as defined... information as set forth in § 122.22(c), and grants electronic clearance via electronic mail or telephone...

  20. General inverse problems for regular variation

    DEFF Research Database (Denmark)

    Damek, Ewa; Mikosch, Thomas Valentin; Rosinski, Jan

    2014-01-01

    Regular variation of distributional tails is known to be preserved by various linear transformations of some random structures. An inverse problem for regular variation aims at understanding whether the regular variation of a transformed random object is caused by regular variation of components ...

  1. PEER INTERACTION IN CLASSES WHICH USE THE CONCEPT OF INCLUSIVE EDUCATION

    Directory of Open Access Journals (Sweden)

    Violeta ARNAUDOVA

    2004-06-01

    Full Text Available We have evaluated a social status of the pupils individually, especially the status of the pupils with developmental disabilities. The sample is convenient and includes 55 pupils from two classes at the age of 9-10 and 13-14 from the regular elementary school “Dimo Hadzi-Dimov”. Children with physical disabilities and anorexic problems are included in both classes. The research has been carried out using socio-metric procedure, applying three socio-metric criteria and both limited and unlimited choices.

  2. Effects of regular exercise on asthma control in young adults.

    Science.gov (United States)

    Heikkinen, Sirpa A M; Mäkikyrö, Elina M S; Hugg, Timo T; Jaakkola, Maritta S; Jaakkola, Jouni J K

    2017-08-28

    According to our systematic literature review, no previous study has assessed potential effects of regular exercise on asthma control among young adults. We hypothesized that regular exercise improves asthma control among young adults. We studied 162 subjects with current asthma recruited from a population-based cohort study of 1,623 young adults 20-27 years of age. Asthma control was assessed by the occurrence of asthma-related symptoms, including wheezing, shortness of breath, cough, and phlegm production, during the past 12 months. Asthma symptom score was calculated based on reported frequencies of these symptoms (range: 0-12). Exercise was assessed as hours/week. In Poisson regression, adjusting for gender, age, smoking, environmental tobacco smoke exposure, and education, the asthma symptom score reduced by 0.09 points per 1 hour of exercise/week (95% CI: 0.00 to 0.17). Applying the "Low exercise" quartile as the reference, "Medium exercise" reduced the asthma symptom score by 0.66 (-0.39 to 1.72), and "High exercise" reduced it significantly by 1.13 (0.03 to 2.22). The effect was strongest among overweight subjects. Our results provide new evidence that regular exercising among young adults improves their asthma control. Thus, advising about exercise should be included as an important part of asthma self-management in clinical practice.

  3. Navy Medicine - World Class Care... Anytime, Anywhere

    Science.gov (United States)

    Search Saturday, May 26th, 2018 Home About Disclaimer Search Navy Medicine Navy Medicine World Class Care... Anytime, Anywhere Home Disclaimer Navy Medicine WebSite About Leadership Readiness Health Partnerships Inside Navy Medicine Dental Corps Hospital Corps Medical Corps Medical Service Corps Nurse Corps

  4. Continuum-regularized quantum gravity

    International Nuclear Information System (INIS)

    Chan Huesum; Halpern, M.B.

    1987-01-01

    The recent continuum regularization of d-dimensional Euclidean gravity is generalized to arbitrary power-law measure and studied in some detail as a representative example of coordinate-invariant regularization. The weak-coupling expansion of the theory illustrates a generic geometrization of regularized Schwinger-Dyson rules, generalizing previous rules in flat space and flat superspace. The rules are applied in a non-trivial explicit check of Einstein invariance at one loop: the cosmological counterterm is computed and its contribution is included in a verification that the graviton mass is zero. (orig.)

  5. Periodontal profile classes predict periodontal disease progression and tooth loss.

    Science.gov (United States)

    Morelli, Thiago; Moss, Kevin L; Preisser, John S; Beck, James D; Divaris, Kimon; Wu, Di; Offenbacher, Steven

    2018-02-01

    Current periodontal disease taxonomies have limited utility for predicting disease progression and tooth loss; in fact, tooth loss itself can undermine precise person-level periodontal disease classifications. To overcome this limitation, the current group recently introduced a novel patient stratification system using latent class analyses of clinical parameters, including patterns of missing teeth. This investigation sought to determine the clinical utility of the Periodontal Profile Classes and Tooth Profile Classes (PPC/TPC) taxonomy for risk assessment, specifically for predicting periodontal disease progression and incident tooth loss. The analytic sample comprised 4,682 adult participants of two prospective cohort studies (Dental Atherosclerosis Risk in Communities Study and Piedmont Dental Study) with information on periodontal disease progression and incident tooth loss. The PPC/TPC taxonomy includes seven distinct PPCs (person-level disease pattern and severity) and seven TPCs (tooth-level disease). Logistic regression modeling was used to estimate relative risks (RR) and 95% confidence intervals (CI) for the association of these latent classes with disease progression and incident tooth loss, adjusting for examination center, race, sex, age, diabetes, and smoking. To obtain personalized outcome propensities, risk estimates associated with each participant's PPC and TPC were combined into person-level composite risk scores (Index of Periodontal Risk [IPR]). Individuals in two PPCs (PPC-G: Severe Disease and PPC-D: Tooth Loss) had the highest tooth loss risk (RR = 3.6; 95% CI = 2.6 to 5.0 and RR = 3.8; 95% CI = 2.9 to 5.1, respectively). PPC-G also had the highest risk for periodontitis progression (RR = 5.7; 95% CI = 2.2 to 14.7). Personalized IPR scores were positively associated with both periodontitis progression and tooth loss. These findings, upon additional validation, suggest that the periodontal/tooth profile classes and the derived

  6. IL26 gene inactivation in Equidae.

    Science.gov (United States)

    Shakhsi-Niaei, M; Drögemüller, M; Jagannathan, V; Gerber, V; Leeb, T

    2013-12-01

    Interleukin-26 (IL26) is a member of the IL10 cytokine family. The IL26 gene is located between two other well-known cytokines genes of this family encoding interferon-gamma (IFNG) and IL22 in an evolutionary conserved gene cluster. In contrast to humans and most other mammals, mice lack a functional Il26 gene. We analyzed the genome sequences of other vertebrates for the presence or absence of functional IL26 orthologs and found that the IL26 gene has also become inactivated in several equid species. We detected a one-base pair frameshift deletion in exon 2 of the IL26 gene in the domestic horse (Equus caballus), Przewalski horse (Equus przewalskii) and donkey (Equus asinus). The remnant IL26 gene in the horse is still transcribed and gives rise to at least five alternative transcripts. None of these transcripts share a conserved open reading frame with the human IL26 gene. A comparative analysis across diverse vertebrates revealed that the IL26 gene has also independently been inactivated in a few other mammals, including the African elephant and the European hedgehog. The IL26 gene thus appears to be highly variable, and the conserved open reading frame has been lost several times during mammalian evolution. © 2013 The Authors, Animal Genetics © 2013 Stichting International Foundation for Animal Genetics.

  7. Homotypic aggregation of human cell lines by HLA class II-, class Ia- and HLA-G-specific monoclonal antibodies

    DEFF Research Database (Denmark)

    Odum, Niels; Ledbetter, J A; Martin, P

    1991-01-01

    Major histocompatibility complex (MHC) class II molecules have been implicated in cell adhesion in two ways. In addition to the well-established role of class II antigens in low-affinity adhesion provided by interactions between class II and CD4, recent data indicated that class II may also induce...... adhesion between T and B cells by activating the CD18/CD11a (LFA-1) adhesion pathway. Here we report that monoclonal antibodies (mAb) against HLA-DR (L243, p4.1, HB10a, VI15) and certain broad class II reacting mAb (TU35, TU39), but not anti-DQ (TU22, Leu-10) mAb, induced homotypic aggregation of human...... class II-positive monocytic (I937) and T leukemic (HUT78) tumor cell lines and Epstein-Barr virus (EBV) transformed B-lymphoid cell lines (EBV-LCL). Class II-negative cell lines (U-937 and the EBV-LCL mutant line 616) were not induced to aggregate. An HLA-G-transfected EBV-LCL, 221-AGN...

  8. 24 CFR 8.26 - Distribution of accessible dwelling units.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Distribution of accessible dwelling units. 8.26 Section 8.26 Housing and Urban Development Office of the Secretary, Department of Housing... accessible dwelling units. Accessible dwelling units required by § 8.22, 8.23, 8.24 or 8.25 shall, to the...

  9. Online co-regularized algorithms

    NARCIS (Netherlands)

    Ruijter, T. de; Tsivtsivadze, E.; Heskes, T.

    2012-01-01

    We propose an online co-regularized learning algorithm for classification and regression tasks. We demonstrate that by sequentially co-regularizing prediction functions on unlabeled data points, our algorithm provides improved performance in comparison to supervised methods on several UCI benchmarks

  10. Freebie Rhabdomyolysis: A Public Health Concern. Spin Class-Induced Rhabdomyolysis.

    Science.gov (United States)

    Brogan, Maureen; Ledesma, Rudrick; Coffino, Alan; Chander, Praveen

    2017-04-01

    Rhabdomyolysis is a pathologic condition in which intracellular muscle constituents leak into the blood circulation. It is usually caused by muscle trauma. "Spinning" is an indoor form of cycling where participants use a special stationary exercise bicycle with a weighted flywheel and undergo high-intensity cycling classes focusing on endurance. There have been several case reports in the literature of exertional rhabdomyolysis following spin class. Our nephrology practices have diagnosed a number of cases of symptomatic patients presenting to our emergency departments following their first spin classes, with histories and creatinine phosphokinase levels diagnostic of exertional rhabdomyolysis. We present 3 unusual cases of exertional rhabdomyolysis, each occurring after a first spin class. In the first case, rhabdomyolysis developed following 15 minutes of spin class. In the second case, it occurred in a young individual who exercises regularly. In the third case, the patient developed biopsy-proved acute kidney injury secondary to exertional rhabdomyolysis and required hemodialysis. The high-intensity exercise associated with "spin class" comes with significant risks to newcomers. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Geometric continuum regularization of quantum field theory

    International Nuclear Information System (INIS)

    Halpern, M.B.

    1989-01-01

    An overview of the continuum regularization program is given. The program is traced from its roots in stochastic quantization, with emphasis on the examples of regularized gauge theory, the regularized general nonlinear sigma model and regularized quantum gravity. In its coordinate-invariant form, the regularization is seen as entirely geometric: only the supermetric on field deformations is regularized, and the prescription provides universal nonperturbative invariant continuum regularization across all quantum field theory. 54 refs

  12. 22 CFR 42.11 - Classification symbols.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Classification symbols. 42.11 Section 42.11... NATIONALITY ACT, AS AMENDED Classification and Foreign State Chargeability § 42.11 Classification symbols. A... visa symbol to show the classification of the alien. Immigrants Symbol Class Section of law Immediate...

  13. Gait and Function in Class III Obesity

    Directory of Open Access Journals (Sweden)

    Catherine Ling

    2012-01-01

    Full Text Available Walking, more specifically gait, is an essential component of daily living. Walking is a very different activity for individuals with a Body Mass Index (BMI of 40 or more (Class III obesity compared with those who are overweight or obese with a BMI between 26–35. Yet all obesity weight classes receive the same physical activity guidelines and recommendations. This observational study examined the components of function and disability in a group with Class III obesity and a group that is overweight or has Class I obesity. Significant differences were found between the groups in the areas of gait, body size, health condition, and activity capacity and participation. The Timed Up and Go test, gait velocity, hip circumference, and stance width appear to be most predictive of activity capacity as observed during gait assessment. The findings indicate that Class III-related gait is pathologic and not a normal adaptation.

  14. Bypassing the Limits of Ll Regularization: Convex Sparse Signal Processing Using Non-Convex Regularization

    Science.gov (United States)

    Parekh, Ankit

    Sparsity has become the basis of some important signal processing methods over the last ten years. Many signal processing problems (e.g., denoising, deconvolution, non-linear component analysis) can be expressed as inverse problems. Sparsity is invoked through the formulation of an inverse problem with suitably designed regularization terms. The regularization terms alone encode sparsity into the problem formulation. Often, the ℓ1 norm is used to induce sparsity, so much so that ℓ1 regularization is considered to be `modern least-squares'. The use of ℓ1 norm, as a sparsity-inducing regularizer, leads to a convex optimization problem, which has several benefits: the absence of extraneous local minima, well developed theory of globally convergent algorithms, even for large-scale problems. Convex regularization via the ℓ1 norm, however, tends to under-estimate the non-zero values of sparse signals. In order to estimate the non-zero values more accurately, non-convex regularization is often favored over convex regularization. However, non-convex regularization generally leads to non-convex optimization, which suffers from numerous issues: convergence may be guaranteed to only a stationary point, problem specific parameters may be difficult to set, and the solution is sensitive to the initialization of the algorithm. The first part of this thesis is aimed toward combining the benefits of non-convex regularization and convex optimization to estimate sparse signals more effectively. To this end, we propose to use parameterized non-convex regularizers with designated non-convexity and provide a range for the non-convex parameter so as to ensure that the objective function is strictly convex. By ensuring convexity of the objective function (sum of data-fidelity and non-convex regularizer), we can make use of a wide variety of convex optimization algorithms to obtain the unique global minimum reliably. The second part of this thesis proposes a non-linear signal

  15. 26 CFR 1.446-2 - Method of accounting for interest.

    Science.gov (United States)

    2010-04-01

    ... account by a taxpayer under the taxpayer's regular method of accounting (e.g., an accrual method or the... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Method of accounting for interest. 1.446-2... TAX (CONTINUED) INCOME TAXES Methods of Accounting § 1.446-2 Method of accounting for interest. (a...

  16. Using Tikhonov Regularization for Spatial Projections from CSR Regularized Spherical Harmonic GRACE Solutions

    Science.gov (United States)

    Save, H.; Bettadpur, S. V.

    2013-12-01

    It has been demonstrated before that using Tikhonov regularization produces spherical harmonic solutions from GRACE that have very little residual stripes while capturing all the signal observed by GRACE within the noise level. This paper demonstrates a two-step process and uses Tikhonov regularization to remove the residual stripes in the CSR regularized spherical harmonic coefficients when computing the spatial projections. We discuss methods to produce mass anomaly grids that have no stripe features while satisfying the necessary condition of capturing all observed signal within the GRACE noise level.

  17. Systemic treatment after whole-brain radiotherapy may improve survival in RPA class II/III breast cancer patients with brain metastasis.

    Science.gov (United States)

    Zhang, Qian; Chen, Jian; Yu, Xiaoli; Ma, Jinli; Cai, Gang; Yang, Zhaozhi; Cao, Lu; Chen, Xingxing; Guo, Xiaomao; Chen, Jiayi

    2013-09-01

    Whole brain radiotherapy (WBRT) is the most widely used treatment for brain metastasis (BM), especially for patients with multiple intracranial lesions. The purpose of this study was to examine the efficacy of systemic treatments following WBRT in breast cancer patients with BM who had different clinical characteristics, based on the classification of the Radiation Therapy Oncology Group recursive partitioning analysis (RPA) and the breast cancer-specific Graded Prognostic Assessment (Breast-GPA). One hundred and one breast cancer patients with BM treated between 2006 and 2010 were analyzed. The median interval between breast cancer diagnosis and identification of BM in the triple-negative patients was shorter than in the luminal A subtype (26 vs. 36 months, respectively; P = 0.021). Univariate analysis indicated that age at BM diagnosis, Karnofsky performance status/recursive partitioning analysis (KPS/RPA) classes, number of BMs, primary tumor control, extracranial metastases and systemic treatment following WBRT were significant prognostic factors for overall survival (OS) (P RPA classes and systemic treatments following WBRT remained the significant prognostic factors for OS. For RPA class I, the median survival with and without systemic treatments following WBRT was 25 and 22 months, respectively (P = 0.819), while for RPA class II/III systemic treatments significantly improved OS from 7 and 2 months to 11 and 5 months, respectively (P RPA class II/III patients.

  18. Drug-drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer.

    Science.gov (United States)

    Park, Gab-Jin; Bae, Soo Hyeon; Park, Wan-Su; Han, Seunghoon; Park, Min-Ho; Shin, Seok-Ho; Shin, Young G; Yim, Dong-Seok

    2017-01-01

    A microdose drug-drug interaction (DDI) study may be a valuable tool for anticipating drug interaction at therapeutic doses. This study aimed to compare the magnitude of DDIs at microdoses and regular doses to explore the applicability of a microdose DDI study. Six healthy male volunteer subjects were enrolled into each DDI study of omeprazole (victim) and known perpetrators: fluconazole (inhibitor) and rifampin (inducer). For both studies, the microdose (100 μg, cold compound) and the regular dose (20 mg) of omeprazole were given at days 0 and 1, respectively. On days 2-9, the inhibitor or inducer was given daily, and the microdose and regular dose of omeprazole were repeated at days 8 and 9, respectively. Full omeprazole pharmacokinetic samplings were performed at days 0, 1, 8, and 9 of both studies for noncompartmental analysis. The magnitude of the DDI, the geometric mean ratios (with perpetrator/omeprazole only) of maximum concentration (C max ) and area under the curve to the last measurement (AUC t ) of the microdose and the regular dose were compared. The geometric mean ratios in the inhibition study were: 2.17 (micro) and 2.68 (regular) for C max , and 4.07 (micro), 4.33 (regular) for AUC t . For the induction study, they were 0.26 (micro) and 0.21 (regular) for C max , and 0.16 (micro) and 0.15 (regular) for AUC t . There were no significant statistical differences in the magnitudes of DDIs between microdose and regular-dose conditions, regardless of induction or inhibition. Our results may be used as partial evidence that microdose DDI studies may replace regular-dose studies, or at least be used for DDI-screening purposes.

  19. Regularity theory for mean-field game systems

    CERN Document Server

    Gomes, Diogo A; Voskanyan, Vardan

    2016-01-01

    Beginning with a concise introduction to the theory of mean-field games (MFGs), this book presents the key elements of the regularity theory for MFGs. It then introduces a series of techniques for well-posedness in the context of mean-field problems, including stationary and time-dependent MFGs, subquadratic and superquadratic MFG formulations, and distinct classes of mean-field couplings. It also explores stationary and time-dependent MFGs through a series of a-priori estimates for solutions of the Hamilton-Jacobi and Fokker-Planck equation. It shows sophisticated a-priori systems derived using a range of analytical techniques, and builds on previous results to explain classical solutions. The final chapter discusses the potential applications, models and natural extensions of MFGs. As MFGs connect common problems in pure mathematics, engineering, economics and data management, this book is a valuable resource for researchers and graduate students in these fields.

  20. Regularity Theory for Mean-Field Game Systems

    KAUST Repository

    Gomes, Diogo A.

    2016-09-14

    Beginning with a concise introduction to the theory of mean-field games (MFGs), this book presents the key elements of the regularity theory for MFGs. It then introduces a series of techniques for well-posedness in the context of mean-field problems, including stationary and time-dependent MFGs, subquadratic and superquadratic MFG formulations, and distinct classes of mean-field couplings. It also explores stationary and time-dependent MFGs through a series of a-priori estimates for solutions of the Hamilton-Jacobi and Fokker-Planck equation. It shows sophisticated a-priori systems derived using a range of analytical techniques, and builds on previous results to explain classical solutions. The final chapter discusses the potential applications, models and natural extensions of MFGs. As MFGs connect common problems in pure mathematics, engineering, economics and data management, this book is a valuable resource for researchers and graduate students in these fields.

  1. Regularity Theory for Mean-Field Game Systems

    KAUST Repository

    Gomes, Diogo A.; Pimentel, Edgard A.; Voskanyan, Vardan K.

    2016-01-01

    Beginning with a concise introduction to the theory of mean-field games (MFGs), this book presents the key elements of the regularity theory for MFGs. It then introduces a series of techniques for well-posedness in the context of mean-field problems, including stationary and time-dependent MFGs, subquadratic and superquadratic MFG formulations, and distinct classes of mean-field couplings. It also explores stationary and time-dependent MFGs through a series of a-priori estimates for solutions of the Hamilton-Jacobi and Fokker-Planck equation. It shows sophisticated a-priori systems derived using a range of analytical techniques, and builds on previous results to explain classical solutions. The final chapter discusses the potential applications, models and natural extensions of MFGs. As MFGs connect common problems in pure mathematics, engineering, economics and data management, this book is a valuable resource for researchers and graduate students in these fields.

  2. Beyond axial symmetry: An improved class of models for global data

    KAUST Repository

    Castruccio, Stefano

    2014-03-01

    An important class of models for data on a spherical domain, called axially symmetric, assumes stationarity across longitudes but not across latitudes. The main aim of this work is to introduce a new and more flexible class of models by relaxing the assumption of longitudinal stationarity in the context of regularly gridded climate model output. In this investigation, two other related topics are discussed: the lack of fit of an axially symmetric parametric model compared with a non-parametric model and to longitudinally reversible processes, an important subclass of axially symmetric models.

  3. Beyond axial symmetry: An improved class of models for global data

    KAUST Repository

    Castruccio, Stefano; Genton, Marc G.

    2014-01-01

    An important class of models for data on a spherical domain, called axially symmetric, assumes stationarity across longitudes but not across latitudes. The main aim of this work is to introduce a new and more flexible class of models by relaxing the assumption of longitudinal stationarity in the context of regularly gridded climate model output. In this investigation, two other related topics are discussed: the lack of fit of an axially symmetric parametric model compared with a non-parametric model and to longitudinally reversible processes, an important subclass of axially symmetric models.

  4. Association analysis of class II cytokine and receptor genes in vitiligo patients.

    Science.gov (United States)

    Traks, Tanel; Karelson, Maire; Reimann, Ene; Rätsep, Ranno; Silm, Helgi; Vasar, Eero; Kõks, Sulev; Kingo, Külli

    2016-05-01

    The loss of melanocytes in vitiligo is mainly attributed to defective autoimmune mechanisms and lately autoinflammatory mediators have become more emphasized. Among these, a number of class II cytokines and their receptors have displayed altered expression patterns in vitiligo. Thus, we selected 30 SNPs from the regions of respective genes to be genotyped in Estonian case-control sample (109 and 328 individuals, respectively). For more precise analyses, patients were divided into subgroups based on vitiligo progression activity, age of onset, sex, occurrence of vitiligo among relatives, extent of depigmented areas, appearance of Köbner's phenomenon, existence of halo nevi, occurrence of spontaneous repigmentation, and amount of thyroid peroxidase antibodies. No associations appeared in whole vitiligo group. In subgroups, several allelic and haplotype associations were found. The strongest involved SNPs rs12301088 (near IL26 gene), that was associated with familial vitiligo and existence of halo nevi, and rs2257167 (IFNAR1 gene), that was associated with female vitiligo. Additionally, haplotypes consisting of rs12301088 and rs12321603 alleles (IL26-IL22 genes), that were associated with familial vitiligo and existence of halo nevi. In conclusion, several genetic associations with vitiligo subphenotypes were revealed and functional explanations to these remain to be determined in respective studies. Copyright © 2016. Published by Elsevier Inc.

  5. 27 CFR 22.104 - Educational organizations, colleges of learning, and scientific universities.

    Science.gov (United States)

    2010-04-01

    ..., colleges of learning, and scientific universities. 22.104 Section 22.104 Alcohol, Tobacco Products and... OF TAX-FREE ALCOHOL Use of Tax-Free Alcohol § 22.104 Educational organizations, colleges of learning... income tax under 26 U.S.C. 501(a). (b) Colleges of learning. Colleges of learning, for the purposes of...

  6. The use of assistive technology resources for disabled children in regular schooling: the teachers’ perception

    Directory of Open Access Journals (Sweden)

    2012-12-01

    Full Text Available The national School Census revealed that 702,603 disabled people were enrolled in regular educationin 2010. The use of assistive technology resources in the school context has been indicated to favor the executionof tasks and the access to educational content and school environments and, consequently, help disabledindividuals’ learning. However, there are few studies showing the impact of these resources in the educationprocess of children with physical disabilities. The aim of this study was to identify, from the teacher’s viewpoint,the contributions and difficulties in the use of technology resources with students with cerebral palsy, focusingon those with severe motor impairment, attending regular education. The study included five teachers of these students who were using assistive technology resources in the execution of writing and/or communicationassignments. Semi-structured interviews were conducted and data were analyzed following the CollectiveSubject Discourse (CSD technique. Results indicated that assistive technology resources are already includedin regular schools and that they have brought contributions to the education process of children with cerebralpalsy in regular class; nevertheless, they are being implemented without systematization, monitoring and/orpartnerships. The study pointed to the need to consider the opinions and requirements of the people involved inthe context where the use of technology is inserted.

  7. Improved Collaborative Representation Classifier Based on l2-Regularized for Human Action Recognition

    Directory of Open Access Journals (Sweden)

    Shirui Huo

    2017-01-01

    Full Text Available Human action recognition is an important recent challenging task. Projecting depth images onto three depth motion maps (DMMs and extracting deep convolutional neural network (DCNN features are discriminant descriptor features to characterize the spatiotemporal information of a specific action from a sequence of depth images. In this paper, a unified improved collaborative representation framework is proposed in which the probability that a test sample belongs to the collaborative subspace of all classes can be well defined and calculated. The improved collaborative representation classifier (ICRC based on l2-regularized for human action recognition is presented to maximize the likelihood that a test sample belongs to each class, then theoretical investigation into ICRC shows that it obtains a final classification by computing the likelihood for each class. Coupled with the DMMs and DCNN features, experiments on depth image-based action recognition, including MSRAction3D and MSRGesture3D datasets, demonstrate that the proposed approach successfully using a distance-based representation classifier achieves superior performance over the state-of-the-art methods, including SRC, CRC, and SVM.

  8. 22 CFR 151.8 - Evidence of insurance for motor vehicles.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Evidence of insurance for motor vehicles. 151.8... LIABILITY INSURANCE FOR DIPLOMATIC MISSIONS AND PERSONNEL § 151.8 Evidence of insurance for motor vehicles... insurance throughout the period of registration on all motor vehicles owned or leased or otherwise regularly...

  9. Regularities of Multifractal Measures

    Indian Academy of Sciences (India)

    First, we prove the decomposition theorem for the regularities of multifractal Hausdorff measure and packing measure in R R d . This decomposition theorem enables us to split a set into regular and irregular parts, so that we can analyze each separately, and recombine them without affecting density properties. Next, we ...

  10. INCLUSION OF CHILDREN WITH SPECIAL EDUCATIONAL NEEDS IN REGULAR SCHOOLS: STUDENTS ATTITUDES AND PERCEPTIONS

    Directory of Open Access Journals (Sweden)

    Ludmila MALCOCI

    2015-07-01

    Full Text Available The Republic of Moldova started the process of deinstitutionalization of children with disabilities/and special educational needs and their inclusion in biological families and mainstream community based services. Alongside with the deinstitutionalization, inclusion of children with special educational needs in regular community schools became a strategic direction of the educational policies in Moldova. In 2014, the Alliance of NGOs in the field of Social Protection of Family and Child conducted a research on assessment of inclusive education models implemented in pilot schools with the aim to identify positive practices, learned lessons and challenges in developing policies in the field of evidence-based education2 The research was conducted in 20 pilot schools from 12 counties. There were interviewed 200 teachers, 20 school managers, 360 students (162 pupils with SEN, 112 students studying in classes with children with SEN and 86 children studying in classes with no students having SEN. 10 focus group discussions with caregivers, students, teachers, parents (all in total 100 participants and 6 interviews with the general directorates of education and mayors were conducted. The article is focused on comparative analysis of perceptions, attitudes and behaviors of students with SEN and typical students regarding the inclusion of children with SEN in regular schools. The author concluded that the implementation of inclusive education resulted in rather positive changes in respective schools: provision with materials, modern devices, improvement of teaching quality and methods, change in the behaviors of children with SEN and in typical children; the typical children have positive attitudes and perceptions regarding the inclusion of children with SEN in their regular community schools; the level of school satisfaction of both: children with SEN and typical children is pretty high; the social and learning environment in pilot schools is friendly

  11. Adaptive Regularization of Neural Classifiers

    DEFF Research Database (Denmark)

    Andersen, Lars Nonboe; Larsen, Jan; Hansen, Lars Kai

    1997-01-01

    We present a regularization scheme which iteratively adapts the regularization parameters by minimizing the validation error. It is suggested to use the adaptive regularization scheme in conjunction with optimal brain damage pruning to optimize the architecture and to avoid overfitting. Furthermo......, we propose an improved neural classification architecture eliminating an inherent redundancy in the widely used SoftMax classification network. Numerical results demonstrate the viability of the method...

  12. Deviant dynamics of EEG resting state pattern in 22q11.2 deletion syndrome adolescents: A vulnerability marker of schizophrenia?

    Science.gov (United States)

    Tomescu, Miralena I; Rihs, Tonia A; Becker, Robert; Britz, Juliane; Custo, Anna; Grouiller, Frédéric; Schneider, Maude; Debbané, Martin; Eliez, Stephan; Michel, Christoph M

    2014-08-01

    Previous studies have repeatedly found altered temporal characteristics of EEG microstates in schizophrenia. The aim of the present study was to investigate whether adolescents affected by the 22q11.2 deletion syndrome (22q11DS), known to have a 30 fold increased risk to develop schizophrenia, already show deviant EEG microstates. If this is the case, temporal alterations of EEG microstates in 22q11DS individuals could be considered as potential biomarkers for schizophrenia. We used high-density (204 channel) EEG to explore between-group microstate differences in 30 adolescents with 22q11DS and 28 age-matched controls. We found an increased presence of one microstate class (class C) in the 22q11DS adolescents with respect to controls that was associated with positive prodromal symptoms (hallucinations). A previous across-age study showed that the class C microstate was more present during adolescence and a combined EEG-fMRI study associated the class C microstate with the salience resting state network, a network known to be dysfunctional in schizophrenia. Therefore, the increased class C microstates could be indexing the increased risk of 22q11DS individuals to develop schizophrenia if confirmed by our ongoing longitudinal study comparing both the adult 22q11DS individuals with and without schizophrenia, as well as schizophrenic individuals with and without 22q11DS. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. Block matching sparsity regularization-based image reconstruction for incomplete projection data in computed tomography

    Science.gov (United States)

    Cai, Ailong; Li, Lei; Zheng, Zhizhong; Zhang, Hanming; Wang, Linyuan; Hu, Guoen; Yan, Bin

    2018-02-01

    In medical imaging many conventional regularization methods, such as total variation or total generalized variation, impose strong prior assumptions which can only account for very limited classes of images. A more reasonable sparse representation frame for images is still badly needed. Visually understandable images contain meaningful patterns, and combinations or collections of these patterns can be utilized to form some sparse and redundant representations which promise to facilitate image reconstructions. In this work, we propose and study block matching sparsity regularization (BMSR) and devise an optimization program using BMSR for computed tomography (CT) image reconstruction for an incomplete projection set. The program is built as a constrained optimization, minimizing the L1-norm of the coefficients of the image in the transformed domain subject to data observation and positivity of the image itself. To solve the program efficiently, a practical method based on the proximal point algorithm is developed and analyzed. In order to accelerate the convergence rate, a practical strategy for tuning the BMSR parameter is proposed and applied. The experimental results for various settings, including real CT scanning, have verified the proposed reconstruction method showing promising capabilities over conventional regularization.

  14. A function space framework for structural total variation regularization with applications in inverse problems

    Science.gov (United States)

    Hintermüller, Michael; Holler, Martin; Papafitsoros, Kostas

    2018-06-01

    In this work, we introduce a function space setting for a wide class of structural/weighted total variation (TV) regularization methods motivated by their applications in inverse problems. In particular, we consider a regularizer that is the appropriate lower semi-continuous envelope (relaxation) of a suitable TV type functional initially defined for sufficiently smooth functions. We study examples where this relaxation can be expressed explicitly, and we also provide refinements for weighted TV for a wide range of weights. Since an integral characterization of the relaxation in function space is, in general, not always available, we show that, for a rather general linear inverse problems setting, instead of the classical Tikhonov regularization problem, one can equivalently solve a saddle-point problem where no a priori knowledge of an explicit formulation of the structural TV functional is needed. In particular, motivated by concrete applications, we deduce corresponding results for linear inverse problems with norm and Poisson log-likelihood data discrepancy terms. Finally, we provide proof-of-concept numerical examples where we solve the saddle-point problem for weighted TV denoising as well as for MR guided PET image reconstruction.

  15. Condition Number Regularized Covariance Estimation.

    Science.gov (United States)

    Won, Joong-Ho; Lim, Johan; Kim, Seung-Jean; Rajaratnam, Bala

    2013-06-01

    Estimation of high-dimensional covariance matrices is known to be a difficult problem, has many applications, and is of current interest to the larger statistics community. In many applications including so-called the "large p small n " setting, the estimate of the covariance matrix is required to be not only invertible, but also well-conditioned. Although many regularization schemes attempt to do this, none of them address the ill-conditioning problem directly. In this paper, we propose a maximum likelihood approach, with the direct goal of obtaining a well-conditioned estimator. No sparsity assumption on either the covariance matrix or its inverse are are imposed, thus making our procedure more widely applicable. We demonstrate that the proposed regularization scheme is computationally efficient, yields a type of Steinian shrinkage estimator, and has a natural Bayesian interpretation. We investigate the theoretical properties of the regularized covariance estimator comprehensively, including its regularization path, and proceed to develop an approach that adaptively determines the level of regularization that is required. Finally, we demonstrate the performance of the regularized estimator in decision-theoretic comparisons and in the financial portfolio optimization setting. The proposed approach has desirable properties, and can serve as a competitive procedure, especially when the sample size is small and when a well-conditioned estimator is required.

  16. A Test of the Reciprocal-Effects Model of Academic Achievement and Academic Self-Concept in Regular Classes and Special Classes for the Gifted

    Science.gov (United States)

    Preckel, Franzis; Schmidt, Isabelle; Stumpf, Eva; Motschenbacher, Monika; Vogl, Katharina; Schneider, Wolfgang

    2017-01-01

    According to the reciprocal-effects model (REM), prior academic self-concept (ASC) has a positive effect on subsequent achievement beyond what can be explained in terms of prior achievement and vice versa. The present study investigated the REM for students studying in special classes for the gifted compared to students studying in regular…

  17. MD SIMULATION STUDIES TO INVESTIGATE ISO-ENERGETIC CONFORMATIONAL BEHAVIOUR OF MODIFIED NUCLEOSIDES M2G AND M22G PRESENT IN tRNA

    Directory of Open Access Journals (Sweden)

    Rohit S Bavi

    2013-02-01

    Full Text Available Modified nucleic acid bases are most commonly found in tRNA. These may contain modifications from simple methylation to addition of bulky groups. Methylation of the four canonical nucleotide bases at a wide variety of positions is particularly prominent among the known modification. Methylation of N2 group of guanine is a relatively common modification in tRNA and rRNA. N2-methylguanosine (m2G is the second most often encountered nucleoside in E. coli tRNAs. N2, N2-dimethylguanosine (m22G is found in the majority of eukaryotic tRNAs and involved in forming base pair interactions with adjacent bases. Hence, in order to understand the structural significance of these methylated nucleic acid bases we have carried out molecular dynamics simulation to see the salvation effect. The results obtained shows iso-energetic conformational behaviors for m2G and m22G. The simulation trajectory of m2G shows regular periodical fluctuations suggesting that m2G is equally stable as either s-cis or s-trans rotamers. The two rotamers of m2G may interact canonically or non-canonically with opposite base as s-trans m2G26:C/A/U44 and s-cis m2G26:A/U44. The free rotations around the C-N bond could be the possible reason for these iso-energetic conformations. Dimethylation of G has almost no influence on base pairing with either A or U. Thus, these results reveal that modified nucleosides m2G and m22G may play an important role to prevent tRNA from adopting the unusual mitochondrial like conformation.

  18. Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

    Science.gov (United States)

    Park, Gab-jin; Bae, Soo Hyeon; Park, Wan-Su; Han, Seunghoon; Park, Min-Ho; Shin, Seok-Ho; Shin, Young G; Yim, Dong-Seok

    2017-01-01

    Purpose A microdose drug–drug interaction (DDI) study may be a valuable tool for anticipating drug interaction at therapeutic doses. This study aimed to compare the magnitude of DDIs at microdoses and regular doses to explore the applicability of a microdose DDI study. Patients and methods Six healthy male volunteer subjects were enrolled into each DDI study of omeprazole (victim) and known perpetrators: fluconazole (inhibitor) and rifampin (inducer). For both studies, the microdose (100 μg, cold compound) and the regular dose (20 mg) of omeprazole were given at days 0 and 1, respectively. On days 2–9, the inhibitor or inducer was given daily, and the microdose and regular dose of omeprazole were repeated at days 8 and 9, respectively. Full omeprazole pharmacokinetic samplings were performed at days 0, 1, 8, and 9 of both studies for noncompartmental analysis. Results The magnitude of the DDI, the geometric mean ratios (with perpetrator/omeprazole only) of maximum concentration (Cmax) and area under the curve to the last measurement (AUCt) of the microdose and the regular dose were compared. The geometric mean ratios in the inhibition study were: 2.17 (micro) and 2.68 (regular) for Cmax, and 4.07 (micro), 4.33 (regular) for AUCt. For the induction study, they were 0.26 (micro) and 0.21 (regular) for Cmax, and 0.16 (micro) and 0.15 (regular) for AUCt. There were no significant statistical differences in the magnitudes of DDIs between microdose and regular-dose conditions, regardless of induction or inhibition. Conclusion Our results may be used as partial evidence that microdose DDI studies may replace regular-dose studies, or at least be used for DDI-screening purposes. PMID:28408803

  19. REGULAR METHOD FOR SYNTHESIS OF BASIC BENT-SQUARES OF RANDOM ORDER

    Directory of Open Access Journals (Sweden)

    A. V. Sokolov

    2016-01-01

    Full Text Available The paper is devoted to the class construction of the most non-linear Boolean bent-functions of any length N = 2k (k = 2, 4, 6…, on the basis of their spectral representation – Agievich bent squares. These perfect algebraic constructions are used as a basis to build many new cryptographic primitives, such as generators of pseudo-random key sequences, crypto graphic S-boxes, etc. Bent-functions also find their application in the construction of C-codes in the systems with code division multiple access (CDMA to provide the lowest possible value of Peak-to-Average Power Ratio (PAPR k = 1, as well as for the construction of error-correcting codes and systems of orthogonal biphasic signals. All the numerous applications of bent-functions relate to the theory of their synthesis. However, regular methods for complete class synthesis of bent-functions of any length N = 2k are currently unknown. The paper proposes a regular synthesis method for the basic Agievich bent squares of any order n, based on a regular operator of dyadic shift. Classification for a complete set of spectral vectors of lengths (l = 8, 16, … based on a criterion of the maximum absolute value and set of absolute values of spectral components has been carried out in the paper. It has been shown that any spectral vector can be a basis for building bent squares. Results of the synthesis for the Agievich bent squares of order n = 8 have been generalized and it has been revealed that there are only 3 basic bent squares for this order, while the other 5 can be obtained with help the operation of step-cyclic shift. All the basic bent squares of order n = 16 have been synthesized that allows to construct the bent-functions of length N = 256. The obtained basic bent squares can be used either for direct synthesis of bent-functions and their practical application or for further research in order to synthesize new structures of bent squares of orders n = 16, 32, 64, …

  20. Regular physical activity modifies smoking-related lung function decline and reduces risk of chronic obstructive pulmonary disease: a population-based cohort study

    DEFF Research Database (Denmark)

    Garcia-Aymerich, J; Lange, Peter; Benet, M

    2007-01-01

    RATIONALE: We have previously reported that regular physical activity reduces risk of chronic obstructive pulmonary disease (COPD) exacerbation. We hypothesized that higher levels of regular physical activity could reduce the risk of COPD by modifying smoking-related lung function decline....... OBJECTIVE: To estimate the longitudinal association between regular physical activity and FEV(1) and FVC decline and COPD risk. METHODS: A population-based sample (n = 6,790) was recruited and assessed with respect to physical activity, smoking, lung function, and other covariates, in Copenhagen in 1981....../yr of FEV(1), P-for-trend = 0.006, and +2.6 and +7.7 ml/yr of FVC, P-for-trend function decline. Active smokers with moderate to high physical activity had...

  1. Characterization Well R-22 Geochemistry Report

    International Nuclear Information System (INIS)

    Patrick Longmire

    2002-01-01

    This report provides analytical results for groundwater collected during four characterization-sampling rounds conducted at well R-22 from March 2001 through March 2002. Characterization well R-22 was sampled from March 6 through 13, 2001; June 19 through 26, 2001; November 30 through December 10, 2001; and February 27 through March 7, 2002. The goal of the characterization efforts was to assess the hydrochemistry and to determine whether or not contaminants are present in the regional aquifer in the vicinity of the well. A geochemical evaluation of the analytical results for the well is also presented in this report

  2. Gene-Based Multiclass Cancer Diagnosis with Class-Selective Rejections

    Science.gov (United States)

    Jrad, Nisrine; Grall-Maës, Edith; Beauseroy, Pierre

    2009-01-01

    Supervised learning of microarray data is receiving much attention in recent years. Multiclass cancer diagnosis, based on selected gene profiles, are used as adjunct of clinical diagnosis. However, supervised diagnosis may hinder patient care, add expense or confound a result. To avoid this misleading, a multiclass cancer diagnosis with class-selective rejection is proposed. It rejects some patients from one, some, or all classes in order to ensure a higher reliability while reducing time and expense costs. Moreover, this classifier takes into account asymmetric penalties dependant on each class and on each wrong or partially correct decision. It is based on ν-1-SVM coupled with its regularization path and minimizes a general loss function defined in the class-selective rejection scheme. The state of art multiclass algorithms can be considered as a particular case of the proposed algorithm where the number of decisions is given by the classes and the loss function is defined by the Bayesian risk. Two experiments are carried out in the Bayesian and the class selective rejection frameworks. Five genes selected datasets are used to assess the performance of the proposed method. Results are discussed and accuracies are compared with those computed by the Naive Bayes, Nearest Neighbor, Linear Perceptron, Multilayer Perceptron, and Support Vector Machines classifiers. PMID:19584932

  3. Induction of Mitochondrial Changes Associated with Oxidative Stress on Very Long Chain Fatty Acids (C22:0, C24:0, or C26:0-Treated Human Neuronal Cells (SK-NB-E

    Directory of Open Access Journals (Sweden)

    Amira Zarrouk

    2012-01-01

    Full Text Available In Alzheimer's disease, lipid alterations point towards peroxisomal dysfunctions. Indeed, a cortical accumulation of saturated very long chain fatty acids (VLCFAs: C22:0, C24:0, C26:0, substrates for peroxisomal β-oxidation, has been found in Alzheimer patients. This study was realized to investigate the effects of VLCFAs at the mitochondrial level since mitochondrial dysfunctions play crucial roles in neurodegeneration. On human neuronal SK-NB-E cells treated with C22:0, C24:0, or C26:0 (0.1–20 μM; 48 h, an inhibition of cell growth and mitochondrial dysfunctions were observed by cell counting with trypan blue, MTT assay, and measurement of mitochondrial transmembrane potential (Δψm with DiOC6(3. A stimulation of oxidative stress was observed with DHE and MitoSOX used to quantify superoxide anion production on whole cells and at the mitochondrial level, respectively. With C24:0 and C26:0, by Western blotting, lower levels of mitochondrial complexes III and IV were detected. After staining with MitoTracker and by transmission electron microscopy used to study mitochondrial topography, mass and morphology, major changes were detected in VLCFAs treated-cells: modification of the cytoplasmic distribution of mitochondria, presence of large mitochondria, enhancement of the mitochondrial mass. Thus, VLCFAs can be potential risk factors contributing to neurodegeneration by inducing neuronal damages via mitochondrial dysfunctions.

  4. Construction of a class of Daubechies type wavelet bases

    International Nuclear Information System (INIS)

    Li Dengfeng; Wu Guochang

    2009-01-01

    Extensive work has been done in the theory and the construction of compactly supported orthonormal wavelet bases of L 2 (R). Some of the most distinguished work was done by Daubechies, who constructed a whole family of such wavelet bases. In this paper, we construct a class of orthonormal wavelet bases by using the principle of Daubechies, and investigate the length of support and the regularity of these wavelet bases.

  5. Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line - Pathways that are shared with and distinct from IL-10

    NARCIS (Netherlands)

    Lejeune, D; Dumoutier, L; Constantinescu, S; Kruijer, W; Schuringa, JJ; Renauld, JC

    2002-01-01

    IL (interleukin)-22 is an IL-10-related cytokine; its main biological activity known thus far is the induction of acute phase reactants in liver and pancreas. IL-22 signals through a receptor that is composed of two chains from the class II cytokine receptor family: IL-22R (also called

  6. Condition Number Regularized Covariance Estimation*

    Science.gov (United States)

    Won, Joong-Ho; Lim, Johan; Kim, Seung-Jean; Rajaratnam, Bala

    2012-01-01

    Estimation of high-dimensional covariance matrices is known to be a difficult problem, has many applications, and is of current interest to the larger statistics community. In many applications including so-called the “large p small n” setting, the estimate of the covariance matrix is required to be not only invertible, but also well-conditioned. Although many regularization schemes attempt to do this, none of them address the ill-conditioning problem directly. In this paper, we propose a maximum likelihood approach, with the direct goal of obtaining a well-conditioned estimator. No sparsity assumption on either the covariance matrix or its inverse are are imposed, thus making our procedure more widely applicable. We demonstrate that the proposed regularization scheme is computationally efficient, yields a type of Steinian shrinkage estimator, and has a natural Bayesian interpretation. We investigate the theoretical properties of the regularized covariance estimator comprehensively, including its regularization path, and proceed to develop an approach that adaptively determines the level of regularization that is required. Finally, we demonstrate the performance of the regularized estimator in decision-theoretic comparisons and in the financial portfolio optimization setting. The proposed approach has desirable properties, and can serve as a competitive procedure, especially when the sample size is small and when a well-conditioned estimator is required. PMID:23730197

  7. Salinity stress induces the production of 2-(2-phenylethyl)chromones and regulates novel classes of responsive genes involved in signal transduction in Aquilaria sinensis calli.

    Science.gov (United States)

    Wang, Xiaohui; Gao, Bowen; Liu, Xiao; Dong, Xianjuan; Zhang, Zhongxiu; Fan, Huiyan; Zhang, Le; Wang, Juan; Shi, Shepo; Tu, Pengfei

    2016-05-26

    dynamic changes in transcript abundance for novel classes of responsive genes involved in signal transduction, including the genes responsible for hormone signal transduction, receptor-like kinases, MAPK cascades, Ca(2+) signal transduction, and transcription factors. This study will aid in selecting the target genes to genetically regulate A. sinensis salt-stress signal transduction and elucidating the biosynthesis of 2-(2-phenylethyl)chromones under salinity stress.

  8. Regularization based on steering parameterized Gaussian filters and a Bhattacharyya distance functional

    Science.gov (United States)

    Lopes, Emerson P.

    2001-08-01

    Template regularization embeds the problem of class separability. In the machine vision perspective, this problem is critical when a textural classification procedure is applied to non-stationary pattern mosaic images. These applications often present low accuracy performance due to disturbance of the classifiers produced by exogenous or endogenous signal regularity perturbations. Natural scene imaging, where the images present certain degree of homogeneity in terms of texture element size or shape (primitives) shows a variety of behaviors, especially varying the preferential spatial directionality. The space-time image pattern characterization is only solved if classification procedures are designed considering the most robust tools within a parallel and hardware perspective. The results to be compared in this paper are obtained using a framework based on multi-resolution, frame and hypothesis approach. Two strategies for the bank of Gabor filters applications are considered: adaptive strategy using the KL transform and fix configuration strategy. The regularization under discussion is accomplished in the pyramid building system instance. The filterings are steering Gaussians controlled by free parameters which are adjusted in accordance with a feedback process driven by hints obtained from sequence of frames interaction functionals pos-processed in the training process and including classification of training set samples as examples. Besides these adjustments there is continuous input data sensitive adaptiveness. The experimental result assessments are focused on two basic issues: Bhattacharyya distance as pattern characterization feature and the combination of KL transform as feature selection and adaptive criterion with the regularization of the pattern Bhattacharyya distance functional (BDF) behavior, using the BDF state separability and symmetry as the main indicators of an optimum framework parameter configuration.

  9. The existence and regularity of time-periodic solutions to the three-dimensional Navier–Stokes equations in the whole space

    International Nuclear Information System (INIS)

    Kyed, Mads

    2014-01-01

    The existence, uniqueness and regularity of time-periodic solutions to the Navier–Stokes equations in the three-dimensional whole space are investigated. We consider the Navier–Stokes equations with a non-zero drift term corresponding to the physical model of a fluid flow around a body that moves with a non-zero constant velocity. The existence of a strong time-periodic solution is shown for small time-periodic data. It is further shown that this solution is unique in a large class of weak solutions that can be considered physically reasonable. Finally, we establish regularity properties for any strong solution regardless of its size. (paper)

  10. The 26th Amendment and Youth Voting Rights.

    Science.gov (United States)

    Schamel, Wynell

    1996-01-01

    Describes learning activities to be used in conjunction with a facsimile of the 92nd Congress's joint resolution passing the 26th Amendment extending the voting franchise to 18-year-olds. These activities include document analysis, time lines, class discussions, and storytelling. Briefly reviews the amendment process. (MJP)

  11. Regular-, irregular-, and pseudo-character processing in Chinese: The regularity effect in normal adult readers

    Directory of Open Access Journals (Sweden)

    Dustin Kai Yan Lau

    2014-03-01

    Full Text Available Background Unlike alphabetic languages, Chinese uses a logographic script. However, the pronunciation of many character’s phonetic radical has the same pronunciation as the character as a whole. These are considered regular characters and can be read through a lexical non-semantic route (Weekes & Chen, 1999. Pseudocharacters are another way to study this non-semantic route. A pseudocharacter is the combination of existing semantic and phonetic radicals in their legal positions resulting in a non-existing character (Ho, Chan, Chung, Lee, & Tsang, 2007. Pseudocharacters can be pronounced by direct derivation from the sound of its phonetic radical. Conversely, if the pronunciation of a character does not follow that of the phonetic radical, it is considered as irregular and can only be correctly read through the lexical-semantic route. The aim of the current investigation was to examine reading aloud in normal adults. We hypothesized that the regularity effect, previously described for alphabetical scripts and acquired dyslexic patients of Chinese (Weekes & Chen, 1999; Wu, Liu, Sun, Chromik, & Zhang, 2014, would also be present in normal adult Chinese readers. Method Participants. Thirty (50% female native Hong Kong Cantonese speakers with a mean age of 19.6 years and a mean education of 12.9 years. Stimuli. Sixty regular-, 60 irregular-, and 60 pseudo-characters (with at least 75% of name agreement in Chinese were matched by initial phoneme, number of strokes and family size. Additionally, regular- and irregular-characters were matched by frequency (low and consistency. Procedure. Each participant was asked to read aloud the stimuli presented on a laptop using the DMDX software. The order of stimuli presentation was randomized. Data analysis. ANOVAs were carried out by participants and items with RTs and errors as dependent variables and type of stimuli (regular-, irregular- and pseudo-character as repeated measures (F1 or between subject

  12. Cosmogenic 22Na and 26Al in samples of lunar ground from a drill column of Moon-24

    International Nuclear Information System (INIS)

    Lavrukhina, A.K.; Povinets, P.; Ustinova, G.K.

    1984-01-01

    The method of low background (β-γ-γ)-spectrometry without destruction of the sample has been used to measure 22 Na and 26 Al radioactivity in samples of lunar ground 24118.4-4, 24143.4-4 apd 24184.4-4 from the ''Luna-24'' drilling column. Equilibrium radioactivity of these cosmoqenic isotopes is calculated by the analytic method. The analysis of theoretical and experimental data shows that at depths lower than approximately 40 cm from the lunar surface the drilling process did not bring about ground mixing in the drilling column. For the last million of years the regolite surface layer in the place of ''Luna-24'' landing remained pracically unchanged, i. e. has not been subjected to intensive effect of some mechanic processes on lunar surface. The average intensity of galactic cosmic rays with the rigidity > 0.5 GV for the last million years within the limits of approximtaely 20% remained stable and corresponded to their modern medium intensity 0.24 particlesxcm -2 xc -1 xsr -1 . The average spectrum of galactic cosmic rays for a million years approximately corresponds to the average spectrum for 1962 or 1971

  13. Escherichia coli O26 IN RAW BUFFALO MILK: PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    A. Rella

    2013-02-01

    Full Text Available Escherichia coli O26 is considered to be one of the most important food-borne pathogen. In this study, 120 buffalo milk samples collected in Lazio and in Apulia regions were tested for the presence of E. coli O26. One buffalo milk sample (0,8% tested positive for E. coli O26; the isolate was positive at the verocytotoxicity test and it showed resistance properties to different antimicrobial classes. These preliminary results highlight the need to monitor the foods of animal origin used for production and eaten by a wide range of persons, respect VTEC organism.

  14. Six world-class research teams to investigate overcoming ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Six world-class research teams to investigate overcoming therapeutic resistance in high fatality cancers. 26 octobre 2017. Together with our partners the Canadian Institutes of Health Research, the Azrieli Foundation and the Israel Science Foundation we are pleased to announce the recipients of the Joint Canada-Israel ...

  15. Regularity effect in prospective memory during aging

    Directory of Open Access Journals (Sweden)

    Geoffrey Blondelle

    2016-10-01

    Full Text Available Background: Regularity effect can affect performance in prospective memory (PM, but little is known on the cognitive processes linked to this effect. Moreover, its impacts with regard to aging remain unknown. To our knowledge, this study is the first to examine regularity effect in PM in a lifespan perspective, with a sample of young, intermediate, and older adults. Objective and design: Our study examined the regularity effect in PM in three groups of participants: 28 young adults (18–30, 16 intermediate adults (40–55, and 25 older adults (65–80. The task, adapted from the Virtual Week, was designed to manipulate the regularity of the various activities of daily life that were to be recalled (regular repeated activities vs. irregular non-repeated activities. We examine the role of several cognitive functions including certain dimensions of executive functions (planning, inhibition, shifting, and binding, short-term memory, and retrospective episodic memory to identify those involved in PM, according to regularity and age. Results: A mixed-design ANOVA showed a main effect of task regularity and an interaction between age and regularity: an age-related difference in PM performances was found for irregular activities (older < young, but not for regular activities. All participants recalled more regular activities than irregular ones with no age effect. It appeared that recalling of regular activities only involved planning for both intermediate and older adults, while recalling of irregular ones were linked to planning, inhibition, short-term memory, binding, and retrospective episodic memory. Conclusion: Taken together, our data suggest that planning capacities seem to play a major role in remembering to perform intended actions with advancing age. Furthermore, the age-PM-paradox may be attenuated when the experimental design is adapted by implementing a familiar context through the use of activities of daily living. The clinical

  16. J-regular rings with injectivities

    OpenAIRE

    Shen, Liang

    2010-01-01

    A ring $R$ is called a J-regular ring if R/J(R) is von Neumann regular, where J(R) is the Jacobson radical of R. It is proved that if R is J-regular, then (i) R is right n-injective if and only if every homomorphism from an $n$-generated small right ideal of $R$ to $R_{R}$ can be extended to one from $R_{R}$ to $R_{R}$; (ii) R is right FP-injective if and only if R is right (J, R)-FP-injective. Some known results are improved.

  17. Building complex carbon skeletons with ethynyl[2.2]paracyclophanes

    Directory of Open Access Journals (Sweden)

    Ina Dix

    2014-08-01

    Full Text Available Ethynyl[2.2]paracyclophanes are shown to be useful substrates for the preparation of complex, highly unsaturated carbon frameworks. Thus both the pseudo-geminal- 2 and the pseudo-ortho-diethynylcyclophane 4 can be dimerized by Glaser coupling to the respective dimers 9/10 and 11/12. Whereas the former isomer pair could not be separated so far, the latter provided the pure diastereomers after extensive column chromatography/recrystallization. Isomer 11 is chiral and could be separated on a column impregnated with cellulose tris(3,5-dimethylphenylcarbamate. The bridge-extended cyclophane precursor 18 furnished the ring-enlarged cyclophanes 19 and 20 on Glaser–Hay coupling. Cross-coupling of 4 and the planar building block 1,2-diethynylbenzene (1 yielded the chiral hetero dimer 22 as the main product. An attempt to prepare the biphenylenophane 27 from the triacetylene 24 by CpCo(CO2-catalyzed cycloisomerization resulted in the formation of the cyclobutadiene Co-complex 26. Besides by their usual spectroscopic and analytical data, the new cyclophanes 11, 12, 19, 20, 22, and 26 were characterized by X-ray structural analysis.

  18. Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk

    Science.gov (United States)

    Broderick, Peter; Chen, Bowang; Johnson, David C; Försti, Asta; Vijayakrishnan, Jayaram; Migliorini, Gabriele; Dobbins, Sara E; Holroyd, Amy; Hose, Dirk; Walker, Brian A; Davies, Faith E; Gregory, Walter A; Jackson, Graham H; Irving, Julie A; Pratt, Guy; Fegan, Chris; Fenton, James AL; Neben, Kai; Hoffmann, Per; Nöthen, Markus M; Mühleisen, Thomas W; Eisele, Lewin; Ross, Fiona M; Straka, Christian; Einsele, Hermann; Langer, Christian; Dörner, Elisabeth; Allan, James M; Jauch, Anna; Morgan, Gareth J; Hemminki, Kari; Houlston, Richard S; Goldschmidt, Hartmut

    2016-01-01

    To identify variants for multiple myeloma risk, we conducted a genome-wide association study with validation in additional series totaling 4,692 cases and 10,990 controls. We identified four risk loci at 3q26.2 (rs10936599, P=8.70x10-14), 6p21.33 (rs2285803, PSORS1C2; P= 9.67x10-11), 17p11.2 (rs4273077, TNFRSF13B; P=7.67x10-9) and 22q13.1 (rs877529, CBX7; P=7.63x10-16). These data provide further evidence for genetic susceptibility to this B-cell hematological malignancy and insight into the biological basis of predisposition. PMID:23955597

  19. Iterative Regularization with Minimum-Residual Methods

    DEFF Research Database (Denmark)

    Jensen, Toke Koldborg; Hansen, Per Christian

    2007-01-01

    subspaces. We provide a combination of theory and numerical examples, and our analysis confirms the experience that MINRES and MR-II can work as general regularization methods. We also demonstrate theoretically and experimentally that the same is not true, in general, for GMRES and RRGMRES their success......We study the regularization properties of iterative minimum-residual methods applied to discrete ill-posed problems. In these methods, the projection onto the underlying Krylov subspace acts as a regularizer, and the emphasis of this work is on the role played by the basis vectors of these Krylov...... as regularization methods is highly problem dependent....

  20. Iterative regularization with minimum-residual methods

    DEFF Research Database (Denmark)

    Jensen, Toke Koldborg; Hansen, Per Christian

    2006-01-01

    subspaces. We provide a combination of theory and numerical examples, and our analysis confirms the experience that MINRES and MR-II can work as general regularization methods. We also demonstrate theoretically and experimentally that the same is not true, in general, for GMRES and RRGMRES - their success......We study the regularization properties of iterative minimum-residual methods applied to discrete ill-posed problems. In these methods, the projection onto the underlying Krylov subspace acts as a regularizer, and the emphasis of this work is on the role played by the basis vectors of these Krylov...... as regularization methods is highly problem dependent....

  1. Intrinsic classes in the Union of European Football Associations soccer team ranking

    Science.gov (United States)

    Ausloos, Marcel

    2014-11-01

    A strong structural regularity of classes is found in soccer teams ranked by the Union of European Football Associations (UEFA) for the time interval 2009-2014. It concerns 424 to 453 teams according to the 5 competition seasons. The analysis is based on the rank-size theory considerations, the size being the UEFA coefficient at the end of a season. Three classes emerge: (i) the few "top" teams, (ii) 300 teams, (iii) the rest of the involved teams (about 150) in the tail of the distribution. There are marked empirical laws describing each class. A 3-parameter Lavalette function is used to describe the concave curving as the rank increases, and to distinguish the the tail from the central behavior.

  2. RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification.

    Directory of Open Access Journals (Sweden)

    Aneeshkumar G Arimbasseri

    2015-12-01

    Full Text Available Control of the differential abundance or activity of tRNAs can be important determinants of gene regulation. RNA polymerase (RNAP III synthesizes all tRNAs in eukaryotes and it derepression is associated with cancer. Maf1 is a conserved general repressor of RNAP III under the control of the target of rapamycin (TOR that acts to integrate transcriptional output and protein synthetic demand toward metabolic economy. Studies in budding yeast have indicated that the global tRNA gene activation that occurs with derepression of RNAP III via maf1-deletion is accompanied by a paradoxical loss of tRNA-mediated nonsense suppressor activity, manifested as an antisuppression phenotype, by an unknown mechanism. We show that maf1-antisuppression also occurs in the fission yeast S. pombe amidst general activation of RNAP III. We used tRNA-HydroSeq to document that little changes occurred in the relative levels of different tRNAs in maf1Δ cells. By contrast, the efficiency of N2,N2-dimethyl G26 (m(22G26 modification on certain tRNAs was decreased in response to maf1-deletion and associated with antisuppression, and was validated by other methods. Over-expression of Trm1, which produces m(22G26, reversed maf1-antisuppression. A model that emerges is that competition by increased tRNA levels in maf1Δ cells leads to m(22G26 hypomodification due to limiting Trm1, reducing the activity of suppressor-tRNASerUCA and accounting for antisuppression. Consistent with this, we show that RNAP III mutations associated with hypomyelinating leukodystrophy decrease tRNA transcription, increase m(22G26 efficiency and reverse antisuppression. Extending this more broadly, we show that a decrease in tRNA synthesis by treatment with rapamycin leads to increased m(22G26 modification and that this response is conserved among highly divergent yeasts and human cells.

  3. Multiple graph regularized protein domain ranking.

    Science.gov (United States)

    Wang, Jim Jing-Yan; Bensmail, Halima; Gao, Xin

    2012-11-19

    Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph model and parameters, and this remains a difficult problem for most of the protein domain ranking methods. To tackle this problem, we have developed the Multiple Graph regularized Ranking algorithm, MultiG-Rank. Instead of using a single graph to regularize the ranking scores, MultiG-Rank approximates the intrinsic manifold of protein domain distribution by combining multiple initial graphs for the regularization. Graph weights are learned with ranking scores jointly and automatically, by alternately minimizing an objective function in an iterative algorithm. Experimental results on a subset of the ASTRAL SCOP protein domain database demonstrate that MultiG-Rank achieves a better ranking performance than single graph regularized ranking methods and pairwise similarity based ranking methods. The problem of graph model and parameter selection in graph regularized protein domain ranking can be solved effectively by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graphs to solving protein domain ranking applications.

  4. Segmentation of urinary bladder in CT urography (CTU) using CLASS with enhanced contour conjoint procedure

    Science.gov (United States)

    Cha, Kenny; Hadjiiski, Lubomir; Chan, Heang-Ping; Cohan, Richard H.; Caoili, Elaine M.; Zhou, Chuan

    2014-03-01

    We are developing a computerized method for bladder segmentation in CT urography (CTU) for computeraided diagnosis of bladder cancer. A challenge for computerized bladder segmentation in CTU is that the bladder often contains regions filled with intravenous (IV) contrast and without contrast. Previously, we proposed a Conjoint Level set Analysis and Segmentation System (CLASS) consisting of four stages: preprocessing and initial segmentation, 3D and 2D level set segmentation, and post-processing. In case the bladder is partially filled with contrast, CLASS segments the non-contrast (NC) region and the contrast (C) filled region separately and conjoins the contours with a Contour Conjoint Procedure (CCP). The CCP is not trivial. Inaccuracies in the NC and C contours may cause CCP to exclude portions of the bladder. To alleviate this problem, we implemented model-guided refinement to propagate the C contour if the level set propagation in the region stops prematurely due to substantial non-uniformity of the contrast. An enhanced CCP with regularized energies further propagates the conjoint contours to the correct bladder boundary. Segmentation performance was evaluated using 70 cases. For all cases, 3D hand segmented contours were obtained as reference standard, and computerized segmentation accuracy was evaluated in terms of average volume intersection %, average % volume error, and average minimum distance. With enhanced CCP, those values were 84.4±10.6%, 8.3±16.1%, 3.4±1.8 mm, respectively. With CLASS, those values were 74.6±13.1%, 19.6±18.6%, 4.4±2.2 mm, respectively. The enhanced CCP improved bladder segmentation significantly (p<0.001) for all three performance measures.

  5. Spectral energy distribution analysis of class I and class II FU Orionis stars

    Energy Technology Data Exchange (ETDEWEB)

    Gramajo, Luciana V.; Gómez, Mercedes [Observatorio Astronómico, Universidad Nacional de Córdoba, Argentina, Laprida 854, 5000 Córdoba (Argentina); Rodón, Javier A., E-mail: luciana@oac.uncor.edu, E-mail: mercedes@oac.uncor.edu, E-mail: jrodon@eso.org [European Southern Observatory, Alonso de Córdova 3107, Vitacura, Casilla 19001, Santiago 19 (Chile)

    2014-06-01

    FU Orionis stars (FUors) are eruptive pre-main sequence objects thought to represent quasi-periodic or recurring stages of enhanced accretion during the low-mass star-forming process. We characterize the sample of known and candidate FUors in a homogeneous and consistent way, deriving stellar and circumstellar parameters for each object. We emphasize the analysis in those parameters that are supposed to vary during the FUor stage. We modeled the spectral energy distributions of 24 of the 26 currently known FUors, using the radiative transfer code of Whitney et al. We compare our models with those obtained by Robitaille et al. for Taurus class II and I sources in quiescence periods by calculating the cumulative distribution of the different parameters. FUors have more massive disks: we find that ∼80% of the disks in FUors are more massive than any Taurus class II and I sources in the sample. Median values for the disk mass accretion rates are ∼10{sup –7} M {sub ☉} yr{sup –1} versus ∼10{sup –5} M {sub ☉} yr{sup –1} for standard young stellar objects (YSOs) and FUors, respectively. While the distributions of envelope mass accretion rates for class I FUors and standard class I objects are similar, FUors, on average, have higher envelope mass accretion rates than standard class II and class I sources. Most FUors (∼70%) have envelope mass accretion rates above 10{sup –7} M {sub ☉} yr{sup –1}. In contrast, 60% of the classical YSO sample has an accretion rate below this value. Our results support the current scenario in which changes experimented by the circumstellar disk explain the observed properties of these stars. However, the increase in the disk mass accretion rate is smaller than theoretically predicted, although in good agreement with previous determinations.

  6. 76 FR 5302 - Proposed Amendment of Class E Airspace; Terre Haute, IN

    Science.gov (United States)

    2011-01-31

    ...-1034; Airspace Docket No. 10-AGL-22] Proposed Amendment of Class E Airspace; Terre Haute, IN AGENCY... action proposes to amend Class E airspace at Terre Haute, IN. Controlled airspace is necessary to... (POINT-IN-SPACE) SIAP at Union Hospital Heliport, Terre Haute, IN. Controlled airspace is needed for the...

  7. Camouflage treatment of skeletal Class III malocclusion with conventional orthodontic therapy.

    Science.gov (United States)

    Park, Jae Hyun; Yu, Joseph; Bullen, Ryan

    2017-04-01

    Nonextraction camouflage treatment along with Class III elastics was used to treat a 39-year-old woman with a skeletal Class III pattern and a low mandibular plane angle and short lower anterior facial height. The total active treatment time was 26 months. Her occlusion, smile esthetics, and soft tissue profile were significantly improved after treatment. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  8. Higher derivative regularization and chiral anomaly

    International Nuclear Information System (INIS)

    Nagahama, Yoshinori.

    1985-02-01

    A higher derivative regularization which automatically leads to the consistent chiral anomaly is analyzed in detail. It explicitly breaks all the local gauge symmetry but preserves global chiral symmetry and leads to the chirally symmetric consistent anomaly. This regularization thus clarifies the physics content contained in the consistent anomaly. We also briefly comment on the application of this higher derivative regularization to massless QED. (author)

  9. NCBI nr-aa BLAST: CBRC-TGUT-22-0001 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-TGUT-22-0001 ref|YP_001287724.1| PE-PGRS family protein [Mycobacterium tuberculosis... F11] gb|ABR06122.1| PE-PGRS family protein [Mycobacterium tuberculosis F11] YP_001287724.1 4e-05 26% ...

  10. Study of regularities in propagation of thermal fatigue cracks

    International Nuclear Information System (INIS)

    Tachkova, N.G.; Sobolev, N.D.; Egorov, V.I.; Rostovtsev, Yu.V.; Ivanov, Yu.S.; Sirotin, V.L.

    1978-01-01

    Regularities in the propagation of thermal fatigue cracks in the Cr-Ni steels of the austenite class depending upon deformation conditions in the crack zone, have been considered. Thin-walled tube samples of the Kh16N40, Kh18N20 and Kh16N15 steels have been tested in the 10O reversible 400 deg C and 100 reversible 500 deg C regimes. The samples have possessed a slot-shaped stress concentrator. Stress intensity pseudocoefficient has been calculated for the correlation of experimental data. The formula for determining crack propagation rate has been obtained. The experiments permit to conclude that propagation rate of thermal fatigue cracks in the above steels depends upon the scope of plastic deformation during a cycle and stress intensity pseudocoefficient, and is determined by plastic deformation resistance during thermal cyclic loading

  11. Harmonic R-matrices for scattering amplitudes and spectral regularization

    Energy Technology Data Exchange (ETDEWEB)

    Ferro, Livia; Plefka, Jan [Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik; Lukowski, Tomasz [Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik; Humboldt-Universitaet, Berlin (Germany). Inst. fuer Mathematik; Humboldt-Univ. Berlin (Germany). IRIS Adlershof; Meneghelli, Carlo [Hamburg Univ. (Germany). Fachbereich 11 - Mathematik; Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Theory Group; Staudacher, Matthias [Humboldt-Universitaet, Berlin (Germany). Inst. fuer Mathematik; Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik; Max-Planck-Institut fuer Gravitationsphysik (Albert-Einstein-Institut), Potsdam (Germany)

    2012-12-15

    Planar N=4 super Yang-Mills appears to be integrable. While this allows to find this theory's exact spectrum, integrability has hitherto been of no direct use for scattering amplitudes. To remedy this, we deform all scattering amplitudes by a spectral parameter. The deformed tree-level four-point function turns out to be essentially the one-loop R-matrix of the integrable N=4 spin chain satisfying the Yang-Baxter equation. Deformed on-shell three-point functions yield novel three-leg R-matrices satisfying bootstrap equations. Finally, we supply initial evidence that the spectral parameter might find its use as a novel symmetry-respecting regulator replacing dimensional regularization. Its physical meaning is a local deformation of particle helicity, a fact which might be useful for a much larger class of non-integrable four-dimensional field theories.

  12. Multiple graph regularized protein domain ranking

    KAUST Repository

    Wang, Jim Jing-Yan

    2012-11-19

    Background: Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph model and parameters, and this remains a difficult problem for most of the protein domain ranking methods.Results: To tackle this problem, we have developed the Multiple Graph regularized Ranking algorithm, MultiG-Rank. Instead of using a single graph to regularize the ranking scores, MultiG-Rank approximates the intrinsic manifold of protein domain distribution by combining multiple initial graphs for the regularization. Graph weights are learned with ranking scores jointly and automatically, by alternately minimizing an objective function in an iterative algorithm. Experimental results on a subset of the ASTRAL SCOP protein domain database demonstrate that MultiG-Rank achieves a better ranking performance than single graph regularized ranking methods and pairwise similarity based ranking methods.Conclusion: The problem of graph model and parameter selection in graph regularized protein domain ranking can be solved effectively by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graphs to solving protein domain ranking applications. 2012 Wang et al; licensee BioMed Central Ltd.

  13. Multiple graph regularized protein domain ranking

    KAUST Repository

    Wang, Jim Jing-Yan; Bensmail, Halima; Gao, Xin

    2012-01-01

    Background: Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph model and parameters, and this remains a difficult problem for most of the protein domain ranking methods.Results: To tackle this problem, we have developed the Multiple Graph regularized Ranking algorithm, MultiG-Rank. Instead of using a single graph to regularize the ranking scores, MultiG-Rank approximates the intrinsic manifold of protein domain distribution by combining multiple initial graphs for the regularization. Graph weights are learned with ranking scores jointly and automatically, by alternately minimizing an objective function in an iterative algorithm. Experimental results on a subset of the ASTRAL SCOP protein domain database demonstrate that MultiG-Rank achieves a better ranking performance than single graph regularized ranking methods and pairwise similarity based ranking methods.Conclusion: The problem of graph model and parameter selection in graph regularized protein domain ranking can be solved effectively by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graphs to solving protein domain ranking applications. 2012 Wang et al; licensee BioMed Central Ltd.

  14. Multiple graph regularized protein domain ranking

    Directory of Open Access Journals (Sweden)

    Wang Jim

    2012-11-01

    Full Text Available Abstract Background Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph model and parameters, and this remains a difficult problem for most of the protein domain ranking methods. Results To tackle this problem, we have developed the Multiple Graph regularized Ranking algorithm, MultiG-Rank. Instead of using a single graph to regularize the ranking scores, MultiG-Rank approximates the intrinsic manifold of protein domain distribution by combining multiple initial graphs for the regularization. Graph weights are learned with ranking scores jointly and automatically, by alternately minimizing an objective function in an iterative algorithm. Experimental results on a subset of the ASTRAL SCOP protein domain database demonstrate that MultiG-Rank achieves a better ranking performance than single graph regularized ranking methods and pairwise similarity based ranking methods. Conclusion The problem of graph model and parameter selection in graph regularized protein domain ranking can be solved effectively by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graphs to solving protein domain ranking applications.

  15. 75 FR 53966 - Regular Meeting

    Science.gov (United States)

    2010-09-02

    ... FARM CREDIT SYSTEM INSURANCE CORPORATION Regular Meeting AGENCY: Farm Credit System Insurance Corporation Board. SUMMARY: Notice is hereby given of the regular meeting of the Farm Credit System Insurance Corporation Board (Board). DATE AND TIME: The meeting of the Board will be held at the offices of the Farm...

  16. 76 FR 1378 - Proposed Amendment of Class E Airspace; Kokomo, IN

    Science.gov (United States)

    2011-01-10

    .... SUPPLEMENTARY INFORMATION: History On August 18, 2010, the FAA published a NPRM to amend Class E airspace... Airport, IN (Lat. 40[deg]42'41'' N., long. 86[deg]22'22'' W.) Peru Municipal Airport, IN (Lat. 40[deg]47...-mile radius of Peru Municipal Airport, and within a 6- mile radius of the Regional Health System...

  17. Work and family life of childrearing women workers in Japan: comparison of non-regular employees with short working hours, non-regular employees with long working hours, and regular employees.

    Science.gov (United States)

    Seto, Masako; Morimoto, Kanehisa; Maruyama, Soichiro

    2006-05-01

    This study assessed the working and family life characteristics, and the degree of domestic and work strain of female workers with different employment statuses and weekly working hours who are rearing children. Participants were the mothers of preschoolers in a large Japanese city. We classified the women into three groups according to the hours they worked and their employment conditions. The three groups were: non-regular employees working less than 30 h a week (n=136); non-regular employees working 30 h or more per week (n=141); and regular employees working 30 h or more a week (n=184). We compared among the groups the subjective values of work, financial difficulties, childcare and housework burdens, psychological effects, and strains such as work and family strain, work-family conflict, and work dissatisfaction. Regular employees were more likely to report job pressures and inflexible work schedules and to experience more strain related to work and family than non-regular employees. Non-regular employees were more likely to be facing financial difficulties. In particular, non-regular employees working longer hours tended to encounter socioeconomic difficulties and often lacked support from family and friends. Female workers with children may have different social backgrounds and different stressors according to their working hours and work status.

  18. Providing Students with Foundational Field Instruction within a 50 Minute Class Period: A Practical Example

    Science.gov (United States)

    Percy, M.

    2014-12-01

    There is a growing recognition among secondary educators and administrators that students need to have a science education that provides connections between familiar classes like biology, chemistry, and physics. Because of this waxing interest in an integrative approach to the sciences, there is a broader push for school districts to offer classes geared towards the earth sciences, a field that incorporates knowledge and skills gleaned from the three core science subjects. Within the contexts of a regular secondary school day on a traditional schedule (45- to 50-minute long classes), it is challenging to engage students in rigorous field-based learning, critical for students to develop a deeper understanding of geosciences content, without requiring extra time outside of the regular schedule. We suggest instruction using common, manmade features like drainage retention ponds to model good field practices and provide students with the opportunity to calculate basic hydrologic budgets, take pH readings, and, if in an area with seasonal rainfall, make observations regarding soils by way of trenching, and near-surface processes, including mass wasting and the effects of vegetation on geomorphology. Gains in student understanding are discussed by analyzing the difference in test scores between exams provided to the students after they had received only in-class instruction, and after they had received field instruction in addition to the in-class lectures. In an advanced setting, students made measurements regarding ion contents and pollution that allowed the classes to practice lab skills while developing a data set that was analyzed after field work was completed. It is posited that similar fieldwork could be an effective approach at an introductory level in post-secondary institutions.

  19. Incremental projection approach of regularization for inverse problems

    Energy Technology Data Exchange (ETDEWEB)

    Souopgui, Innocent, E-mail: innocent.souopgui@usm.edu [The University of Southern Mississippi, Department of Marine Science (United States); Ngodock, Hans E., E-mail: hans.ngodock@nrlssc.navy.mil [Naval Research Laboratory (United States); Vidard, Arthur, E-mail: arthur.vidard@imag.fr; Le Dimet, François-Xavier, E-mail: ledimet@imag.fr [Laboratoire Jean Kuntzmann (France)

    2016-10-15

    This paper presents an alternative approach to the regularized least squares solution of ill-posed inverse problems. Instead of solving a minimization problem with an objective function composed of a data term and a regularization term, the regularization information is used to define a projection onto a convex subspace of regularized candidate solutions. The objective function is modified to include the projection of each iterate in the place of the regularization. Numerical experiments based on the problem of motion estimation for geophysical fluid images, show the improvement of the proposed method compared with regularization methods. For the presented test case, the incremental projection method uses 7 times less computation time than the regularization method, to reach the same error target. Moreover, at convergence, the incremental projection is two order of magnitude more accurate than the regularization method.

  20. Adaptive regularization

    DEFF Research Database (Denmark)

    Hansen, Lars Kai; Rasmussen, Carl Edward; Svarer, C.

    1994-01-01

    Regularization, e.g., in the form of weight decay, is important for training and optimization of neural network architectures. In this work the authors provide a tool based on asymptotic sampling theory, for iterative estimation of weight decay parameters. The basic idea is to do a gradient desce...

  1. Self-reported symptoms and risk factors for digital ischaemia among international world-class beach volleyball players.

    Science.gov (United States)

    Van De Pol, Daan; Alaeikhanehshir, Sena; Maas, Mario; Kuijer, P Paul F M

    2016-01-01

    The prevalence of ischaemia-related symptoms is remarkably high among elite indoor volleyball players. Since the exposure to sport-specific demands may be higher in beach volleyball compared to indoor volleyball, the aim of this study was to assess the prevalence of ischaemia-related symptoms and associated risk factors among world-class beach volleyball players. Therefore, a questionnaire survey was performed among beach volleyball players active during the 2013 Grand Slam Beach Volleyball in the Netherlands. In total, 60 of the 128 beach volleyball players (47%) participated: 26 males and 34 females from 17 countries. The self-reported prevalence of cold or blue or pale digits in the dominant hand during or immediately after practice or competition was 38% (n = 23). Two risk factors were independently associated with symptoms of blue or pale digits: more than 14 years playing volleyball (odds ratio (OR) 4.42, 90% confidence interval (90% CI) 1.30-15.07) and sex (female) (OR 4.62, 90% CI 1.15-18.57). In conclusion, the prevalence of symptoms associated with digital ischaemia is high among international world-class beach volleyball players. Female sex and the length of the volleyball career were independently associated with an increased risk of ischaemia-related symptoms. The high prevalence of these seemingly innocuous symptoms and possible associated risk factors warrant regular monitoring since early detection can potentially prevent thromboembolic complications and irreversible tissue damage.

  2. The Class Size Question: A Study at Different Levels of Analysis. ACER Research Monograph No. 26.

    Science.gov (United States)

    Larkin, Anthony I.; Keeves, John P.

    The purpose of this investigation was to examine the ways in which class size affected other facets of the educational environment of the classroom. The study focused on the commonly found positive relationship between class size and achievement. The most plausible explanation of the evidence seems to involve the effects of grouping more able…

  3. Regularizing portfolio optimization

    International Nuclear Information System (INIS)

    Still, Susanne; Kondor, Imre

    2010-01-01

    The optimization of large portfolios displays an inherent instability due to estimation error. This poses a fundamental problem, because solutions that are not stable under sample fluctuations may look optimal for a given sample, but are, in effect, very far from optimal with respect to the average risk. In this paper, we approach the problem from the point of view of statistical learning theory. The occurrence of the instability is intimately related to over-fitting, which can be avoided using known regularization methods. We show how regularized portfolio optimization with the expected shortfall as a risk measure is related to support vector regression. The budget constraint dictates a modification. We present the resulting optimization problem and discuss the solution. The L2 norm of the weight vector is used as a regularizer, which corresponds to a diversification 'pressure'. This means that diversification, besides counteracting downward fluctuations in some assets by upward fluctuations in others, is also crucial because it improves the stability of the solution. The approach we provide here allows for the simultaneous treatment of optimization and diversification in one framework that enables the investor to trade off between the two, depending on the size of the available dataset.

  4. Regularizing portfolio optimization

    Science.gov (United States)

    Still, Susanne; Kondor, Imre

    2010-07-01

    The optimization of large portfolios displays an inherent instability due to estimation error. This poses a fundamental problem, because solutions that are not stable under sample fluctuations may look optimal for a given sample, but are, in effect, very far from optimal with respect to the average risk. In this paper, we approach the problem from the point of view of statistical learning theory. The occurrence of the instability is intimately related to over-fitting, which can be avoided using known regularization methods. We show how regularized portfolio optimization with the expected shortfall as a risk measure is related to support vector regression. The budget constraint dictates a modification. We present the resulting optimization problem and discuss the solution. The L2 norm of the weight vector is used as a regularizer, which corresponds to a diversification 'pressure'. This means that diversification, besides counteracting downward fluctuations in some assets by upward fluctuations in others, is also crucial because it improves the stability of the solution. The approach we provide here allows for the simultaneous treatment of optimization and diversification in one framework that enables the investor to trade off between the two, depending on the size of the available dataset.

  5. New fuzzy support vector machine for the class imbalance problem in medical datasets classification.

    Science.gov (United States)

    Gu, Xiaoqing; Ni, Tongguang; Wang, Hongyuan

    2014-01-01

    In medical datasets classification, support vector machine (SVM) is considered to be one of the most successful methods. However, most of the real-world medical datasets usually contain some outliers/noise and data often have class imbalance problems. In this paper, a fuzzy support machine (FSVM) for the class imbalance problem (called FSVM-CIP) is presented, which can be seen as a modified class of FSVM by extending manifold regularization and assigning two misclassification costs for two classes. The proposed FSVM-CIP can be used to handle the class imbalance problem in the presence of outliers/noise, and enhance the locality maximum margin. Five real-world medical datasets, breast, heart, hepatitis, BUPA liver, and pima diabetes, from the UCI medical database are employed to illustrate the method presented in this paper. Experimental results on these datasets show the outperformed or comparable effectiveness of FSVM-CIP.

  6. New Fuzzy Support Vector Machine for the Class Imbalance Problem in Medical Datasets Classification

    Directory of Open Access Journals (Sweden)

    Xiaoqing Gu

    2014-01-01

    Full Text Available In medical datasets classification, support vector machine (SVM is considered to be one of the most successful methods. However, most of the real-world medical datasets usually contain some outliers/noise and data often have class imbalance problems. In this paper, a fuzzy support machine (FSVM for the class imbalance problem (called FSVM-CIP is presented, which can be seen as a modified class of FSVM by extending manifold regularization and assigning two misclassification costs for two classes. The proposed FSVM-CIP can be used to handle the class imbalance problem in the presence of outliers/noise, and enhance the locality maximum margin. Five real-world medical datasets, breast, heart, hepatitis, BUPA liver, and pima diabetes, from the UCI medical database are employed to illustrate the method presented in this paper. Experimental results on these datasets show the outperformed or comparable effectiveness of FSVM-CIP.

  7. Regular physical activity attenuates the blood pressure response to public speaking and delays the development of hypertension.

    Science.gov (United States)

    Palatini, Paolo; Bratti, Paolo; Palomba, Daniela; Saladini, Francesca; Zanatta, Nello; Maraglino, Giuseppe

    2010-06-01

    The objective of this study was to investigate the effect of regular physical activity on the haemodynamic response to public speaking and to evaluate the long-term effect of exercise on development of hypertension. We assessed 75 sedentary and 44 active participants screened for stage 1 hypertension with consistent activity habits and 63 normotensive individuals as control. The blood pressure (BP) response to public speaking was assessed with beat-to-beat noninvasive recording. Definition of incident hypertension was based either on clinic or 24-h BP measurement. The BP response to public speaking was greater in the hypertensive than the normotensive participants (P=0.018/0.009). Among the former, sedentary participants showed increased BP reactivity to the speech test (45.2+/-22.6/22.2+/-11.5mmHg, Ppublic speaking into the Cox model influenced the strength of the association only marginally [hazard ratio=0.55 (95% CI 0.30-0.97) and hazard ratio=0.59 (95% CI 0.36-0.99), respectively]. Regular physical activity attenuates the BP reaction to psychosocial stressors. However, this mechanism seems to be only partially responsible for the long-term effect of exercise on BP.

  8. Spatial analysis of "crazy quilts", a class of potentially random aesthetic artefacts.

    Directory of Open Access Journals (Sweden)

    Gesche Westphal-Fitch

    Full Text Available Human artefacts in general are highly structured and often display ordering principles such as translational, reflectional or rotational symmetry. In contrast, human artefacts that are intended to appear random and non symmetrical are very rare. Furthermore, many studies show that humans find it extremely difficult to recognize or reproduce truly random patterns or sequences. Here, we attempt to model two-dimensional decorative spatial patterns produced by humans that show no obvious order. "Crazy quilts" represent a historically important style of quilt making that became popular in the 1870s, and lasted about 50 years. Crazy quilts are unusual because unlike most human artefacts, they are specifically intended to appear haphazard and unstructured. We evaluate the degree to which this intention was achieved by using statistical techniques of spatial point pattern analysis to compare crazy quilts with regular quilts from the same region and era and to evaluate the fit of various random distributions to these two quilt classes. We found that the two quilt categories exhibit fundamentally different spatial characteristics: The patch areas of crazy quilts derive from a continuous random distribution, while area distributions of regular quilts consist of Gaussian mixtures. These Gaussian mixtures derive from regular pattern motifs that are repeated and we suggest that such a mixture is a distinctive signature of human-made visual patterns. In contrast, the distribution found in crazy quilts is shared with many other naturally occurring spatial patterns. Centroids of patches in the two quilt classes are spaced differently and in general, crazy quilts but not regular quilts are well-fitted by a random Strauss process. These results indicate that, within the constraints of the quilt format, Victorian quilters indeed achieved their goal of generating random structures.

  9. Spatial analysis of "crazy quilts", a class of potentially random aesthetic artefacts.

    Science.gov (United States)

    Westphal-Fitch, Gesche; Fitch, W Tecumseh

    2013-01-01

    Human artefacts in general are highly structured and often display ordering principles such as translational, reflectional or rotational symmetry. In contrast, human artefacts that are intended to appear random and non symmetrical are very rare. Furthermore, many studies show that humans find it extremely difficult to recognize or reproduce truly random patterns or sequences. Here, we attempt to model two-dimensional decorative spatial patterns produced by humans that show no obvious order. "Crazy quilts" represent a historically important style of quilt making that became popular in the 1870s, and lasted about 50 years. Crazy quilts are unusual because unlike most human artefacts, they are specifically intended to appear haphazard and unstructured. We evaluate the degree to which this intention was achieved by using statistical techniques of spatial point pattern analysis to compare crazy quilts with regular quilts from the same region and era and to evaluate the fit of various random distributions to these two quilt classes. We found that the two quilt categories exhibit fundamentally different spatial characteristics: The patch areas of crazy quilts derive from a continuous random distribution, while area distributions of regular quilts consist of Gaussian mixtures. These Gaussian mixtures derive from regular pattern motifs that are repeated and we suggest that such a mixture is a distinctive signature of human-made visual patterns. In contrast, the distribution found in crazy quilts is shared with many other naturally occurring spatial patterns. Centroids of patches in the two quilt classes are spaced differently and in general, crazy quilts but not regular quilts are well-fitted by a random Strauss process. These results indicate that, within the constraints of the quilt format, Victorian quilters indeed achieved their goal of generating random structures.

  10. Tessellating the Sphere with Regular Polygons

    Science.gov (United States)

    Soto-Johnson, Hortensia; Bechthold, Dawn

    2004-01-01

    Tessellations in the Euclidean plane and regular polygons that tessellate the sphere are reviewed. The regular polygons that can possibly tesellate the sphere are spherical triangles, squares and pentagons.

  11. Effect of a common diet and regular beverage on enamel erosion in various temperatures: an in-vitro study.

    Science.gov (United States)

    Khamverdi, Zahra; Vahedi, Mohammad; Abdollahzadeh, Shermin; Ghambari, Mohammad Hosein

    2013-09-01

    This study compared diet and regular Coca-Cola on enamel erosion in cold and room temperatures. Seventy five enamel specimens were prepared and divided into 5 equal groups (N=15) as follows: Group 1: regular beverage at room temperature, Group 2: regular beverage at refri-gerator temperature, Group 3: diet beverage at room and Group 4: diet beverage at refrige-rator temperature. The specimens were immersed in the regular or diet beverage (Coca-Cola, trade mark regd. Khoshgovar Co., Tehran, Iran) at room (20°C) or refrigerator (2°C) temperatures for 20 minutes, 3 times per day for 7 days. Specimens in the control subjects (group 5) were placed in synthetic saliva at room temperature for 7 days. The hardness of specimens was tested using Vickers test under 500 gr loads for 5 seconds. The data were analyzed using two-way ANOVA and Tukey tests. The mean and standard deviations of micro-hardness values of the studied groups were as follow: G1: 304.26±29.71, G2: 285.53±42.14, G3: 279.06±39.52, G4: 266.80±23.98 and G5: 319± 30.79. There was a significant difference in the beverage type as the main factor (p0.05). Tukey tests showed that there were significant differences between control and diet groups as well as regular and diet groups. Diet Coca-Cola is more erosive than the regular type and the temperature of the beverages used had no significant influence on enamel erosion.

  12. Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-06-22 to 2010-06-26 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069050)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-06-22 to 2010-06-26 in...

  13. Accretion onto some well-known regular black holes

    International Nuclear Information System (INIS)

    Jawad, Abdul; Shahzad, M.U.

    2016-01-01

    In this work, we discuss the accretion onto static spherically symmetric regular black holes for specific choices of the equation of state parameter. The underlying regular black holes are charged regular black holes using the Fermi-Dirac distribution, logistic distribution, nonlinear electrodynamics, respectively, and Kehagias-Sftesos asymptotically flat regular black holes. We obtain the critical radius, critical speed, and squared sound speed during the accretion process near the regular black holes. We also study the behavior of radial velocity, energy density, and the rate of change of the mass for each of the regular black holes. (orig.)

  14. Accretion onto some well-known regular black holes

    Energy Technology Data Exchange (ETDEWEB)

    Jawad, Abdul; Shahzad, M.U. [COMSATS Institute of Information Technology, Department of Mathematics, Lahore (Pakistan)

    2016-03-15

    In this work, we discuss the accretion onto static spherically symmetric regular black holes for specific choices of the equation of state parameter. The underlying regular black holes are charged regular black holes using the Fermi-Dirac distribution, logistic distribution, nonlinear electrodynamics, respectively, and Kehagias-Sftesos asymptotically flat regular black holes. We obtain the critical radius, critical speed, and squared sound speed during the accretion process near the regular black holes. We also study the behavior of radial velocity, energy density, and the rate of change of the mass for each of the regular black holes. (orig.)

  15. Accretion onto some well-known regular black holes

    Science.gov (United States)

    Jawad, Abdul; Shahzad, M. Umair

    2016-03-01

    In this work, we discuss the accretion onto static spherically symmetric regular black holes for specific choices of the equation of state parameter. The underlying regular black holes are charged regular black holes using the Fermi-Dirac distribution, logistic distribution, nonlinear electrodynamics, respectively, and Kehagias-Sftesos asymptotically flat regular black holes. We obtain the critical radius, critical speed, and squared sound speed during the accretion process near the regular black holes. We also study the behavior of radial velocity, energy density, and the rate of change of the mass for each of the regular black holes.

  16. 27 CFR 5.22 - The standards of identity.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false The standards of identity..., DEPARTMENT OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF DISTILLED SPIRITS Standards of Identity for Distilled Spirits § 5.22 The standards of identity. Standards of identity for the several classes and types...

  17. 22 CFR 11.5 - Certification for appointment to class 7 or 8.

    Science.gov (United States)

    2010-04-01

    ... abroad (to a maximum of 2 years of such civilian service), or Peace Corps volunteer service, will be... examination in a foreign language, but the appointment will be subject to the condition that the newly..., adequate proficiency in a foreign language is achieved. (22 U.S.C. 1221 et seq.) [37 FR 19356, Sept. 20...

  18. Clinical, immunological and genetic features in eleven Algerian patients with major histocompatibility complex class II expression deficiency

    Directory of Open Access Journals (Sweden)

    Djidjik Réda

    2012-08-01

    Full Text Available Abstract Presenting processed antigens to CD4+ lymphocytes during the immune response involves major histocompatibility complex class II molecules. MHC class II genes transcription is regulated by four transcription factors: CIITA, RFXANK, RFX5 and RFXAP. Defects in these factors result in major histocompatibility complex class II expression deficiency, a primary combined immunodeficiency frequent in North Africa. Autosomal recessive mutations in the RFXANK gene have been reported as being the principal defect found in North African patients with this disorder. In this paper, we describe clinical, immunological and genetic features of 11 unrelated Algerian patients whose monocytes display a total absence of MHC class II molecules. They shared mainly the same clinical picture which included protracted diarrhoea and respiratory tract recurrent infections. Genetic analysis revealed that 9 of the 11 patients had the same RFXANK founder mutation, a 26 bp deletion (named I5E6-25_I5E6+1, also known as 752delG26. Immunological and genetic findings in our series may facilitate genetic counselling implementation for Algerian consanguineous families. Further studies need to be conducted to determine 752delG26 heterozygous mutation frequency in Algerian population.

  19. Diagrammatic methods in phase-space regularization

    International Nuclear Information System (INIS)

    Bern, Z.; Halpern, M.B.; California Univ., Berkeley

    1987-11-01

    Using the scalar prototype and gauge theory as the simplest possible examples, diagrammatic methods are developed for the recently proposed phase-space form of continuum regularization. A number of one-loop and all-order applications are given, including general diagrammatic discussions of the nogrowth theorem and the uniqueness of the phase-space stochastic calculus. The approach also generates an alternate derivation of the equivalence of the large-β phase-space regularization to the more conventional coordinate-space regularization. (orig.)

  20. Metric regularity and subdifferential calculus

    International Nuclear Information System (INIS)

    Ioffe, A D

    2000-01-01

    The theory of metric regularity is an extension of two classical results: the Lyusternik tangent space theorem and the Graves surjection theorem. Developments in non-smooth analysis in the 1980s and 1990s paved the way for a number of far-reaching extensions of these results. It was also well understood that the phenomena behind the results are of metric origin, not connected with any linear structure. At the same time it became clear that some basic hypotheses of the subdifferential calculus are closely connected with the metric regularity of certain set-valued maps. The survey is devoted to the metric theory of metric regularity and its connection with subdifferential calculus in Banach spaces

  1. Hysteresis and Phase Transitions in a Lattice Regularization of an Ill-Posed Forward-Backward Diffusion Equation

    Science.gov (United States)

    Helmers, Michael; Herrmann, Michael

    2018-03-01

    We consider a lattice regularization for an ill-posed diffusion equation with a trilinear constitutive law and study the dynamics of phase interfaces in the parabolic scaling limit. Our main result guarantees for a certain class of single-interface initial data that the lattice solutions satisfy asymptotically a free boundary problem with a hysteretic Stefan condition. The key challenge in the proof is to control the microscopic fluctuations that are inevitably produced by the backward diffusion when a particle passes the spinodal region.

  2. Temporal regularity of the environment drives time perception

    OpenAIRE

    van Rijn, H; Rhodes, D; Di Luca, M

    2016-01-01

    It’s reasonable to assume that a regularly paced sequence should be perceived as regular, but here we show that perceived regularity depends on the context in which the sequence is embedded. We presented one group of participants with perceptually regularly paced sequences, and another group of participants with mostly irregularly paced sequences (75% irregular, 25% regular). The timing of the final stimulus in each sequence could be var- ied. In one experiment, we asked whether the last stim...

  3. Optimal dividend policies with transaction costs for a class of jump-diffusion processes

    DEFF Research Database (Denmark)

    Hunting, Martin; Paulsen, Jostein

    2013-01-01

    his paper addresses the problem of finding an optimal dividend policy for a class of jump-diffusion processes. The jump component is a compound Poisson process with negative jumps, and the drift and diffusion components are assumed to satisfy some regularity and growth restrictions. Each dividend...... payment is changed by a fixed and a proportional cost, meaning that if ξ is paid out by the company, the shareholders receive kξ−K, where k and K are positive. The aim is to maximize expected discounted dividends until ruin. It is proved that when the jumps belong to a certain class of light...

  4. Regularization of the big bang singularity with random perturbations

    Science.gov (United States)

    Belbruno, Edward; Xue, BingKan

    2018-03-01

    We show how to regularize the big bang singularity in the presence of random perturbations modeled by Brownian motion using stochastic methods. We prove that the physical variables in a contracting universe dominated by a scalar field can be continuously and uniquely extended through the big bang as a function of time to an expanding universe only for a discrete set of values of the equation of state satisfying special co-prime number conditions. This result significantly generalizes a previous result (Xue and Belbruno 2014 Class. Quantum Grav. 31 165002) that did not model random perturbations. This result implies that the extension from a contracting to an expanding universe for the discrete set of co-prime equation of state is robust, which is a surprising result. Implications for a purely expanding universe are discussed, such as a non-smooth, randomly varying scale factor near the big bang.

  5. The uniqueness of the regularization procedure

    International Nuclear Information System (INIS)

    Brzezowski, S.

    1981-01-01

    On the grounds of the BPHZ procedure, the criteria of correct regularization in perturbation calculations of QFT are given, together with the prescription for dividing the regularized formulas into the finite and infinite parts. (author)

  6. Coupling regularizes individual units in noisy populations

    International Nuclear Information System (INIS)

    Ly Cheng; Ermentrout, G. Bard

    2010-01-01

    The regularity of a noisy system can modulate in various ways. It is well known that coupling in a population can lower the variability of the entire network; the collective activity is more regular. Here, we show that diffusive (reciprocal) coupling of two simple Ornstein-Uhlenbeck (O-U) processes can regularize the individual, even when it is coupled to a noisier process. In cellular networks, the regularity of individual cells is important when a select few play a significant role. The regularizing effect of coupling surprisingly applies also to general nonlinear noisy oscillators. However, unlike with the O-U process, coupling-induced regularity is robust to different kinds of coupling. With two coupled noisy oscillators, we derive an asymptotic formula assuming weak noise and coupling for the variance of the period (i.e., spike times) that accurately captures this effect. Moreover, we find that reciprocal coupling can regularize the individual period of higher dimensional oscillators such as the Morris-Lecar and Brusselator models, even when coupled to noisier oscillators. Coupling can have a counterintuitive and beneficial effect on noisy systems. These results have implications for the role of connectivity with noisy oscillators and the modulation of variability of individual oscillators.

  7. 5 CFR 551.421 - Regular working hours.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Regular working hours. 551.421 Section... Activities § 551.421 Regular working hours. (a) Under the Act there is no requirement that a Federal employee... distinction based on whether the activity is performed by an employee during regular working hours or outside...

  8. A Disorder of Menstrual Function Regularization and its Influence on a Female Reproductive Potential

    Directory of Open Access Journals (Sweden)

    Oksana Makarchuk

    2017-10-01

    Full Text Available Obstetric complications in women of reproductive age are often the result of puberty disorders which remain underestimated and not taken into account in pregnancy monitoring programs in such patients, leading to an increase of habitual non-carrying of pregnancy and negative obstetric effects. The objective of the research is to carry out a comprehensive multivariate assessment of the disturbances of the body adaptive processes in teenage girls, taking into account the data of anamnesis regarding the specifics of menstrual function regularization during puberty, and to determine the main factors of complicated pregnancy in this category of patients. Materials and methods. To carry out the task, 110 pregnant women with a disorder of menstrual function regularizationhave been prospectively examined (the main group; the examination was performed at the preconception stage and in the periods of 6-12, 22-24 and 32-36 weeks of pregnancy. The comparison group consisted of 30 patients with a normal menstrual cycle. In order to identify risk factors and predict complications, the odds ratio (OR and its 95% confidence interval were used. Results. Extragenital pathology plays a significant role in the formation of pathological course of puberty and obstetric complications; 87.27% ofsuch cases were demonstrated in our study. Among the disorders of the ovarian-menstrual cycle, the structural significance is characteristic to the failure of the luteal phase and anovulatory disorders (78.18% of cases. Gynaecologic pathology includes inflammatory diseases of the pelvic organs (35.45%, cervical background processes (41.66%, ovarian tumour lesions (21.81, and primary infertility(14.54%. The obtained results of the structure of pregnancy complications in patients of the main group show reproductive losses in early pregnancy (11.8%, subchorionic hematoma (28.18% and the threat of late spontaneous abortion; these data are notedthree times more often than in the

  9. Regular non-twisting S-branes

    International Nuclear Information System (INIS)

    Obregon, Octavio; Quevedo, Hernando; Ryan, Michael P.

    2004-01-01

    We construct a family of time and angular dependent, regular S-brane solutions which corresponds to a simple analytical continuation of the Zipoy-Voorhees 4-dimensional vacuum spacetime. The solutions are asymptotically flat and turn out to be free of singularities without requiring a twist in space. They can be considered as the simplest non-singular generalization of the singular S0-brane solution. We analyze the properties of a representative of this family of solutions and show that it resembles to some extent the asymptotic properties of the regular Kerr S-brane. The R-symmetry corresponds, however, to the general lorentzian symmetry. Several generalizations of this regular solution are derived which include a charged S-brane and an additional dilatonic field. (author)

  10. 76 FR 6322 - Brucellosis Class Free States and Certified Brucellosis-Free Herds; Revisions to Testing and...

    Science.gov (United States)

    2011-02-04

    ... reclassification of any Class Free State or area to a lower status if two or more herds are found to have.... APHIS-2009-0083] RIN 0579-AD22 Brucellosis Class Free States and Certified Brucellosis-Free Herds... Class Free States. This action will allow interested persons additional time to prepare and submit...

  11. Resolutions and other decisions of the general conference. Thirty-ninth regular session. 18-22 September 1995

    International Nuclear Information System (INIS)

    1996-03-01

    The twenty-four resolutions adopted and the seventeen other decisions taken by the General Conference at its thirty-ninth (1995) regular session are reproduced in this booklet. The resolutions are, for ease of reference, preceded by the agenda for the session. Before the title of each resolution a serial number is given by which it may be cited. Any footnotes to a resolution appear immediately after the text on the left side of the page; on the right side are given the date of the adoption of the resolution, the relevant agenda item and a reference to the record of the meeting at which the resolution was adopted. The other decisions taken by the Conference are presented similarly. This booklet should be read in conjunction with the summary records of the General Conference, where details of the proceedings, including voting results, are contained (GC(39)/OR.1-10)

  12. Resolutions and other decisions of the general conference. Thirty-ninth regular session. 18-22 September 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The twenty-four resolutions adopted and the seventeen other decisions taken by the General Conference at its thirty-ninth (1995) regular session are reproduced in this booklet. The resolutions are, for ease of reference, preceded by the agenda for the session. Before the title of each resolution a serial number is given by which it may be cited. Any footnotes to a resolution appear immediately after the text on the left side of the page; on the right side are given the date of the adoption of the resolution, the relevant agenda item and a reference to the record of the meeting at which the resolution was adopted. The other decisions taken by the Conference are presented similarly. This booklet should be read in conjunction with the summary records of the General Conference, where details of the proceedings, including voting results, are contained (GC(39)/OR.1-10).

  13. Regular group exercise contributes to balanced health in older adults in Japan: a qualitative study.

    Science.gov (United States)

    Komatsu, Hiroko; Yagasaki, Kaori; Saito, Yoshinobu; Oguma, Yuko

    2017-08-22

    While community-wide interventions to promote physical activity have been encouraged in older adults, evidence of their effectiveness remains limited. We conducted a qualitative study among older adults participating in regular group exercise to understand their perceptions of the physical, mental, and social changes they underwent as a result of the physical activity. We conducted a qualitative study with purposeful sampling to explore the experiences of older adults who participated in regular group exercise as part of a community-wide physical activity intervention. Four focus group interviews were conducted between April and June of 2016 at community halls in Fujisawa City. The participants in the focus group interviews were 26 older adults with a mean age of 74.69 years (range: 66-86). The interviews were analysed using the constant comparative method in the grounded theory approach. We used qualitative research software NVivo10® to track the coding and manage the data. The finding 'regular group exercise contributes to balanced health in older adults' emerged as an overarching theme with seven categories (regular group exercise, functional health, active mind, enjoyment, social connectedness, mutual support, and expanding communities). Although the participants perceived that they were aging physically and cognitively, the regular group exercise helped them to improve or maintain their functional health and enjoy their lives. They felt socially connected and experienced a sense of security in the community through caring for others and supporting each other. As the older adults began to seek value beyond individuals, they gradually expanded their communities beyond geographical and generational boundaries. The participants achieved balanced health in the physical, mental, and social domains through regular group exercise as part of a community-wide physical activity intervention and contributed to expanding communities through social connectedness and

  14. Near-Regular Structure Discovery Using Linear Programming

    KAUST Repository

    Huang, Qixing

    2014-06-02

    Near-regular structures are common in manmade and natural objects. Algorithmic detection of such regularity greatly facilitates our understanding of shape structures, leads to compact encoding of input geometries, and enables efficient generation and manipulation of complex patterns on both acquired and synthesized objects. Such regularity manifests itself both in the repetition of certain geometric elements, as well as in the structured arrangement of the elements. We cast the regularity detection problem as an optimization and efficiently solve it using linear programming techniques. Our optimization has a discrete aspect, that is, the connectivity relationships among the elements, as well as a continuous aspect, namely the locations of the elements of interest. Both these aspects are captured by our near-regular structure extraction framework, which alternates between discrete and continuous optimizations. We demonstrate the effectiveness of our framework on a variety of problems including near-regular structure extraction, structure-preserving pattern manipulation, and markerless correspondence detection. Robustness results with respect to geometric and topological noise are presented on synthesized, real-world, and also benchmark datasets. © 2014 ACM.

  15. 77 FR 64599 - Change in Rates and Classes of General Applicability for Competitive Products

    Science.gov (United States)

    2012-10-22

    ... Distribution Center (RNDC) will have a 1.0 percent overall increase, and prices for parcels picked up at a... Vol. 77 Monday, No. 204 October 22, 2012 Part II Postal Service Change in Rates and Classes of..., October 22, 2012 / Notices#0;#0; [[Page 64600

  16. Regular exercise behaviour and intention and symptoms of anxiety and depression in coronary heart disease patients across Europe: Results from the EUROASPIRE III survey.

    Science.gov (United States)

    Prugger, Christof; Wellmann, Jürgen; Heidrich, Jan; De Bacquer, Dirk; De Smedt, Delphine; De Backer, Guy; Reiner, Željko; Empana, Jean-Philippe; Fras, Zlatko; Gaita, Dan; Jennings, Catriona; Kotseva, Kornelia; Wood, David; Keil, Ulrich

    2017-01-01

    Regular exercise lowers the risk of cardiovascular death in coronary heart disease (CHD) patients. We aimed to investigate regular exercise behaviour and intention in relation to symptoms of anxiety and depression in CHD patients across Europe. This study was based on a multicentre cross-sectional survey. In the EUROpean Action on Secondary and Primary Prevention through Intervention to Reduce Events (EUROASPIRE) III survey, 8966 CHD patients patients exercised or intended to exercise regularly was assessed using the Stages of Change questionnaire in 8330 patients. Symptoms of anxiety and depression were evaluated using the Hospital Anxiety and Depression Scale. Total physical activity was measured by the International Physical Activity Questionnaire in patients from a subset of 14 countries. Overall, 50.3% of patients were not intending to exercise regularly, 15.9% were intending to exercise regularly, and 33.8% were exercising regularly. Patients with severe symptoms of depression less frequently exercised regularly than patients with symptoms in the normal range (20.2%, 95% confidence interval (CI) 14.8-26.8 vs 36.7%, 95% CI 29.8-44.2). Among patients not exercising regularly, patients with severe symptoms of depression were less likely to have an intention to exercise regularly (odds ratio 0.62, 95% CI 0.46-0.85). Symptoms of anxiety did not affect regular exercise intention. In sensitivity analysis, results were consistent when adjusting for total physical activity. Lower frequency of regular exercise and decreased likelihood of exercise intention were observed in CHD patients with severe depressive symptoms. Severe symptoms of depression may preclude CHD patients from performing regular exercise. © The European Society of Cardiology 2016.

  17. Regular Expression Matching and Operational Semantics

    Directory of Open Access Journals (Sweden)

    Asiri Rathnayake

    2011-08-01

    Full Text Available Many programming languages and tools, ranging from grep to the Java String library, contain regular expression matchers. Rather than first translating a regular expression into a deterministic finite automaton, such implementations typically match the regular expression on the fly. Thus they can be seen as virtual machines interpreting the regular expression much as if it were a program with some non-deterministic constructs such as the Kleene star. We formalize this implementation technique for regular expression matching using operational semantics. Specifically, we derive a series of abstract machines, moving from the abstract definition of matching to increasingly realistic machines. First a continuation is added to the operational semantics to describe what remains to be matched after the current expression. Next, we represent the expression as a data structure using pointers, which enables redundant searches to be eliminated via testing for pointer equality. From there, we arrive both at Thompson's lockstep construction and a machine that performs some operations in parallel, suitable for implementation on a large number of cores, such as a GPU. We formalize the parallel machine using process algebra and report some preliminary experiments with an implementation on a graphics processor using CUDA.

  18. Tetravalent one-regular graphs of order 4p2

    DEFF Research Database (Denmark)

    Feng, Yan-Quan; Kutnar, Klavdija; Marusic, Dragan

    2014-01-01

    A graph is one-regular if its automorphism group acts regularly on the set of its arcs. In this paper tetravalent one-regular graphs of order 4p2, where p is a prime, are classified.......A graph is one-regular if its automorphism group acts regularly on the set of its arcs. In this paper tetravalent one-regular graphs of order 4p2, where p is a prime, are classified....

  19. Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

    Directory of Open Access Journals (Sweden)

    Park G

    2017-03-01

    Full Text Available Gab-jin Park,1 Soo Hyeon Bae,1 Wan-Su Park,1 Seunghoon Han,1 Min-Ho Park,2 Seok-Ho Shin,2 Young G Shin,2 Dong-Seok Yim1,2 1Department of Clinical Pharmacology and Therapeutics, Seoul St Mary’s Hospital, PIPET (Pharmacometrics Institute for Practical Education and Training, College of Medicine, Catholic University of Korea, Seoul, South Korea; 2College of Pharmacy, Chungnam National University, Daejeon, South Korea Purpose: A microdose drug–drug interaction (DDI study may be a valuable tool for anticipating drug interaction at therapeutic doses. This study aimed to compare the magnitude of DDIs at microdoses and regular doses to explore the applicability of a microdose DDI study. Patients and methods: Six healthy male volunteer subjects were enrolled into each DDI study of omeprazole (victim and known perpetrators: fluconazole (inhibitor and rifampin (inducer. For both studies, the microdose (100 µg, cold compound and the regular dose (20 mg of omeprazole were given at days 0 and 1, respectively. On days 2–9, the inhibitor or inducer was given daily, and the microdose and regular dose of omeprazole were repeated at days 8 and 9, respectively. Full omeprazole pharmacokinetic samplings were performed at days 0, 1, 8, and 9 of both studies for noncompartmental analysis. Results: The magnitude of the DDI, the geometric mean ratios (with perpetrator/omeprazole only of maximum concentration (Cmax and area under the curve to the last measurement (AUCt of the microdose and the regular dose were compared. The geometric mean ratios in the inhibition study were: 2.17 (micro and 2.68 (regular for Cmax, and 4.07 (micro, 4.33 (regular for AUCt. For the induction study, they were 0.26 (micro and 0.21 (regular for Cmax, and 0.16 (micro and 0.15 (regular for AUCt. There were no significant statistical differences in the magnitudes of DDIs between microdose and regular-dose conditions, regardless of induction or inhibition. Conclusion: Our results may be

  20. Iron stores in regular blood donors in Lagos, Nigeria

    Directory of Open Access Journals (Sweden)

    Adediran A

    2013-06-01

    Full Text Available Adewumi Adediran,1 Ebele I Uche,2 Titilope A Adeyemo,1 Dapus O Damulak,3 Akinsegun A Akinbami,4 Alani S Akanmu1 1Department of Hematology and Blood Transfusion, University of Lagos, Lagos, Nigeria; 2Department of Hematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos, Nigeria; 3Department of Hematology and Blood Transfusion, Jos University Teaching Hospital, Jos, Nigeria; 4Department of Hematology and Blood Transfusion, Lagos State University, Ikeja, Nigeria Background: Apart from challenging the bone marrow to increase its red cell production, thereby producing more blood for the donor, regular blood donation has been shown to have several benefits, one of which is preventing accumulation of body iron which can cause free radical formation in the body. This study was carried out to assess body iron stores in regular blood donors. Methods: A total of 52 regular (study and 30 first-time (control volunteer blood donors were studied prospectively. Twenty milliliters of venous blood was drawn from each subject, 5 mL of which was put into sodium ethylenediamine tetra-acetic acid specimen bottles for a full blood count, including red blood cell indices. The remaining sample was allowed to clot in a plain container, and the serum was then retrieved for serum ferritin, serum iron, and serum transferrin receptor measurement by enzyme-linked immunosorbent assay. Results: Mean hemoglobin and packed cell volume in the study group (13.47 ± 2.36 g/dL and 42.00 ± 7.10, respectively, P = 0.303 were not significantly higher than in the control group (12.98 ± 1.30 g/dL and 39.76 ± 4.41, respectively, P = 0.119. Mean serum ferritin was 102.46 ± 80.26 ng/mL in the control group and 41.46 ± 40.33 ng/mL in the study group (P = 0.001. Mean serum ferritin for women in the study group (28.02 ± 25.00 ng/mL was significantly lower than for women in the control group (56.35 ± 34.03 ng/mL, P = 0.014. Similarly, men in the study group had a lower

  1. Regularization and error assignment to unfolded distributions

    CERN Document Server

    Zech, Gunter

    2011-01-01

    The commonly used approach to present unfolded data only in graphical formwith the diagonal error depending on the regularization strength is unsatisfac-tory. It does not permit the adjustment of parameters of theories, the exclusionof theories that are admitted by the observed data and does not allow the com-bination of data from different experiments. We propose fixing the regulariza-tion strength by a p-value criterion, indicating the experimental uncertaintiesindependent of the regularization and publishing the unfolded data in additionwithout regularization. These considerations are illustrated with three differentunfolding and smoothing approaches applied to a toy example.

  2. Spatial Analysis of “Crazy Quilts”, a Class of Potentially Random Aesthetic Artefacts

    Science.gov (United States)

    Westphal-Fitch, Gesche; Fitch, W. Tecumseh

    2013-01-01

    Human artefacts in general are highly structured and often display ordering principles such as translational, reflectional or rotational symmetry. In contrast, human artefacts that are intended to appear random and non symmetrical are very rare. Furthermore, many studies show that humans find it extremely difficult to recognize or reproduce truly random patterns or sequences. Here, we attempt to model two-dimensional decorative spatial patterns produced by humans that show no obvious order. “Crazy quilts” represent a historically important style of quilt making that became popular in the 1870s, and lasted about 50 years. Crazy quilts are unusual because unlike most human artefacts, they are specifically intended to appear haphazard and unstructured. We evaluate the degree to which this intention was achieved by using statistical techniques of spatial point pattern analysis to compare crazy quilts with regular quilts from the same region and era and to evaluate the fit of various random distributions to these two quilt classes. We found that the two quilt categories exhibit fundamentally different spatial characteristics: The patch areas of crazy quilts derive from a continuous random distribution, while area distributions of regular quilts consist of Gaussian mixtures. These Gaussian mixtures derive from regular pattern motifs that are repeated and we suggest that such a mixture is a distinctive signature of human-made visual patterns. In contrast, the distribution found in crazy quilts is shared with many other naturally occurring spatial patterns. Centroids of patches in the two quilt classes are spaced differently and in general, crazy quilts but not regular quilts are well-fitted by a random Strauss process. These results indicate that, within the constraints of the quilt format, Victorian quilters indeed achieved their goal of generating random structures. PMID:24066095

  3. Discovery of a New Class of Sortase A Transpeptidase Inhibitors to Tackle Gram-Positive Pathogens: 2-(2-Phenylhydrazinylidenealkanoic Acids and Related Derivatives

    Directory of Open Access Journals (Sweden)

    Benedetta Maggio

    2016-02-01

    Full Text Available A FRET-based random screening assay was used to generate hit compounds as sortase A inhibitors that allowed us to identify ethyl 3-oxo-2-(2-phenylhydrazinylidenebutanoate as an example of a new class of sortase A inhibitors. Other analogues were generated by changing the ethoxycarbonyl function for a carboxy, cyano or amide group, or introducing substituents in the phenyl ring of the ester and acid derivatives. The most active derivative found was 3-oxo-2-(2-(3,4dichlorophenylhydrazinylidenebutanoic acid (2b, showing an IC50 value of 50 µM. For a preliminary assessment of their antivirulence properties the new derivatives were tested for their antibiofilm activity. The most active compound resulted 2a, which showed inhibition of about 60% against S. aureus ATCC 29213, S. aureus ATCC 25923, S. aureus ATCC 6538 and S. epidermidis RP62A at a screening concentration of 100 µM.

  4. Higher order total variation regularization for EIT reconstruction.

    Science.gov (United States)

    Gong, Bo; Schullcke, Benjamin; Krueger-Ziolek, Sabine; Zhang, Fan; Mueller-Lisse, Ullrich; Moeller, Knut

    2018-01-08

    Electrical impedance tomography (EIT) attempts to reveal the conductivity distribution of a domain based on the electrical boundary condition. This is an ill-posed inverse problem; its solution is very unstable. Total variation (TV) regularization is one of the techniques commonly employed to stabilize reconstructions. However, it is well known that TV regularization induces staircase effects, which are not realistic in clinical applications. To reduce such artifacts, modified TV regularization terms considering a higher order differential operator were developed in several previous studies. One of them is called total generalized variation (TGV) regularization. TGV regularization has been successively applied in image processing in a regular grid context. In this study, we adapted TGV regularization to the finite element model (FEM) framework for EIT reconstruction. Reconstructions using simulation and clinical data were performed. First results indicate that, in comparison to TV regularization, TGV regularization promotes more realistic images. Graphical abstract Reconstructed conductivity changes located on selected vertical lines. For each of the reconstructed images as well as the ground truth image, conductivity changes located along the selected left and right vertical lines are plotted. In these plots, the notation GT in the legend stands for ground truth, TV stands for total variation method, and TGV stands for total generalized variation method. Reconstructed conductivity distributions from the GREIT algorithm are also demonstrated.

  5. Application of Turchin's method of statistical regularization

    Science.gov (United States)

    Zelenyi, Mikhail; Poliakova, Mariia; Nozik, Alexander; Khudyakov, Alexey

    2018-04-01

    During analysis of experimental data, one usually needs to restore a signal after it has been convoluted with some kind of apparatus function. According to Hadamard's definition this problem is ill-posed and requires regularization to provide sensible results. In this article we describe an implementation of the Turchin's method of statistical regularization based on the Bayesian approach to the regularization strategy.

  6. On the regularized fermionic projector of the vacuum

    Science.gov (United States)

    Finster, Felix

    2008-03-01

    We construct families of fermionic projectors with spherically symmetric regularization, which satisfy the condition of a distributional MP-product. The method is to analyze regularization tails with a power law or logarithmic scaling in composite expressions in the fermionic projector. The resulting regularizations break the Lorentz symmetry and give rise to a multilayer structure of the fermionic projector near the light cone. Furthermore, we construct regularizations which go beyond the distributional MP-product in that they yield additional distributional contributions supported at the origin. The remaining freedom for the regularization parameters and the consequences for the normalization of the fermionic states are discussed.

  7. On the regularized fermionic projector of the vacuum

    International Nuclear Information System (INIS)

    Finster, Felix

    2008-01-01

    We construct families of fermionic projectors with spherically symmetric regularization, which satisfy the condition of a distributional MP-product. The method is to analyze regularization tails with a power law or logarithmic scaling in composite expressions in the fermionic projector. The resulting regularizations break the Lorentz symmetry and give rise to a multilayer structure of the fermionic projector near the light cone. Furthermore, we construct regularizations which go beyond the distributional MP-product in that they yield additional distributional contributions supported at the origin. The remaining freedom for the regularization parameters and the consequences for the normalization of the fermionic states are discussed

  8. The Majority Rule Act. EdSource Election Brief: Proposition 26.

    Science.gov (United States)

    EdSource, Inc., Palo Alto, CA.

    This article summarizes "The Majority Rule Act for Smaller Classes, Safer Schools and Financial Accountability" (Proposition 26). The Majority Rule Act deals with the percentage vote that a school district, county office of education, or community college, needs in an election to authorize local general-obligation bonds for school…

  9. Teacher Effectiveness in Adapting Instruction to the Needs of Pupils With Learning Difficulties in Regular Primary Schools in Ghana

    Directory of Open Access Journals (Sweden)

    Abdul-Razak Kuyini Alhassan

    2014-01-01

    Full Text Available Ghana education system has failed to effectively address the needs of pupils with learning difficulties (LDs in regular classrooms. Underachievement, school dropout, streetism, and antisocial behaviors are the consequences. Teachers’ lack of adequate competence in adaptive instruction is one of the fundamental reasons responsible for this anomaly. This study aims to examine teachers’ competence in adapting instructions to teach pupils with LDs in the regular classroom in Ghana. The data were gathered from 387 sampled teachers in a cross-sectional survey using questionnaires and structured observation methods. We analyzed the data using descriptive statistic, chi-square test, correlation, t test, and ANOVA. The results show that (a teachers have limited to moderate competence in adaptive instruction, (b adaptive teaching is strongly associated with teachers’ competence in teaching pupils with LDs in the regular classroom, and (c apart from gender and class size, teachers’ background variables such as school location and teaching experience differ significantly. The study has serious implications for Ghana’s inclusive education policy and teaching practice.

  10. Primordial Regular Black Holes: Thermodynamics and Dark Matter

    Directory of Open Access Journals (Sweden)

    José Antonio de Freitas Pacheco

    2018-05-01

    Full Text Available The possibility that dark matter particles could be constituted by extreme regular primordial black holes is discussed. Extreme black holes have zero surface temperature, and are not subjected to the Hawking evaporation process. Assuming that the common horizon radius of these black holes is fixed by the minimum distance that is derived from the Riemann invariant computed from loop quantum gravity, the masses of these non-singular stable black holes are of the order of the Planck mass. However, if they are formed just after inflation, during reheating, their initial masses are about six orders of magnitude higher. After a short period of growth by the accretion of relativistic matter, they evaporate until reaching the extreme solution. Only a fraction of 3.8 × 10−22 of relativistic matter is required to be converted into primordial black holes (PBHs in order to explain the present abundance of dark matter particles.

  11. The Effect of Regular Physical Education in the Transformation Motor Development of Children with Special Needs

    Directory of Open Access Journals (Sweden)

    Danilo Bojanić

    2016-02-01

    Full Text Available The aim of the research is to determine the level of quantitative changes of motor abilities of pupils with special needs under the influence of kinetic activity regular physical education teaching. The survey was conducted on students of the Centre for children and youth with special needs in Mostar, the city of Los Rosales in Mostar and day care facilities for children with special needs in Niksic. The sample was composed of boys of 46 subjects, who were involved in regular physical education for a period of one school year. The level of quantitative and qualitative changes in motor skills, written under the influence of kinesiology operators within regular school physical education classes, was estimated by applying appropriate tests of motor skills, selected in accordance with the degree of mental ability and biological age. Manifest variables applied in this experiment were processed using standard descriptive methods in order to determine their distribution function and basic function parameters. Comparisons of results of measures of central dispersion parameters initial and final measurement, it is evident that the applied program of physical education and sport contribute to changing the distribution of central and dispersion parameters, and that the same distribution of the final measurement closer to the normal distribution of results.

  12. Regularization modeling for large-eddy simulation

    NARCIS (Netherlands)

    Geurts, Bernardus J.; Holm, D.D.

    2003-01-01

    A new modeling approach for large-eddy simulation (LES) is obtained by combining a "regularization principle" with an explicit filter and its inversion. This regularization approach allows a systematic derivation of the implied subgrid model, which resolves the closure problem. The central role of

  13. 40 CFR 82.17 - Apportionment of baseline production allowances for class II controlled substances.

    Science.gov (United States)

    2010-07-01

    ... allowances for class II controlled substances. 82.17 Section 82.17 Protection of Environment ENVIRONMENTAL... Consumption Controls § 82.17 Apportionment of baseline production allowances for class II controlled... 1,759,681 MDA Manufacturing HCFC-22 2,383,835 Solvay Solexis HCFC-142b 6,541,764 [ 74 FR 66446, Dec...

  14. Spatially-Variant Tikhonov Regularization for Double-Difference Waveform Inversion

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Youzuo [Los Alamos National Laboratory; Huang, Lianjie [Los Alamos National Laboratory; Zhang, Zhigang [Los Alamos National Laboratory

    2011-01-01

    Double-difference waveform inversion is a potential tool for quantitative monitoring for geologic carbon storage. It jointly inverts time-lapse seismic data for changes in reservoir geophysical properties. Due to the ill-posedness of waveform inversion, it is a great challenge to obtain reservoir changes accurately and efficiently, particularly when using time-lapse seismic reflection data. Regularization techniques can be utilized to address the issue of ill-posedness. The regularization parameter controls the smoothness of inversion results. A constant regularization parameter is normally used in waveform inversion, and an optimal regularization parameter has to be selected. The resulting inversion results are a trade off among regions with different smoothness or noise levels; therefore the images are either over regularized in some regions while under regularized in the others. In this paper, we employ a spatially-variant parameter in the Tikhonov regularization scheme used in double-difference waveform tomography to improve the inversion accuracy and robustness. We compare the results obtained using a spatially-variant parameter with those obtained using a constant regularization parameter and those produced without any regularization. We observe that, utilizing a spatially-variant regularization scheme, the target regions are well reconstructed while the noise is reduced in the other regions. We show that the spatially-variant regularization scheme provides the flexibility to regularize local regions based on the a priori information without increasing computational costs and the computer memory requirement.

  15. 26 CFR 48.6416(b)(2)-2 - Exportations, uses, sales, and resales included.

    Science.gov (United States)

    2010-04-01

    ..., section 4091 (aviation fuel tax), or section 4121 (coal tax). (b) Exportation of tax-paid articles—(1) In... TREASURY (CONTINUED) MISCELLANEOUS EXCISE TAXES MANUFACTURERS AND RETAILERS EXCISE TAXES Refunds and Other Administrative Provisions of Special Application to Retailers and Manufacturers Taxes § 48.6416(b)(2)-2...

  16. Manifold Regularized Correlation Object Tracking.

    Science.gov (United States)

    Hu, Hongwei; Ma, Bo; Shen, Jianbing; Shao, Ling

    2018-05-01

    In this paper, we propose a manifold regularized correlation tracking method with augmented samples. To make better use of the unlabeled data and the manifold structure of the sample space, a manifold regularization-based correlation filter is introduced, which aims to assign similar labels to neighbor samples. Meanwhile, the regression model is learned by exploiting the block-circulant structure of matrices resulting from the augmented translated samples over multiple base samples cropped from both target and nontarget regions. Thus, the final classifier in our method is trained with positive, negative, and unlabeled base samples, which is a semisupervised learning framework. A block optimization strategy is further introduced to learn a manifold regularization-based correlation filter for efficient online tracking. Experiments on two public tracking data sets demonstrate the superior performance of our tracker compared with the state-of-the-art tracking approaches.

  17. From recreational to regular drug use

    DEFF Research Database (Denmark)

    Järvinen, Margaretha; Ravn, Signe

    2011-01-01

    This article analyses the process of going from recreational use to regular and problematic use of illegal drugs. We present a model containing six career contingencies relevant for young people’s progress from recreational to regular drug use: the closing of social networks, changes in forms...

  18. Are Complex Magnetic Field Structures Responsible for the Confined X-class Flares in Super Active Region 12192?

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Jun; Li, Ting; Chen, Huadong, E-mail: zjun@nao.cas.cn, E-mail: hdchen@nao.cas.cn [Key Laboratory of Solar Activity, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China)

    2017-08-10

    From 2014 October 19 to 27, six X-class flares occurred in super active region (AR) 12192. They were all confined flares and were not followed by coronal mass ejections. To examine the structures of the four flares close to the solar disk center from October 22 to 26, we firstly employ composite triple-time images in each flare process to display the stratified structure of these flare loops. The loop structures of each flare in both the lower (171 Å) and higher (131 Å) temperature channels are complex, e.g., the flare loops rooting at flare ribbons are sheared or twisted (enwound) together, and the complex structures were not destroyed during the flares. For the first flare, although the flare loop system appears as a spindle shape, we can estimate its structures from observations, with lengths ranging from 130 to 300 Mm, heights from 65 to 150 Mm, widths at the middle part of the spindle from 40 to 100 Mm, and shear angles from 16° to 90°. Moreover, the flare ribbons display irregular movements, such as the left ribbon fragments of the flare on October 22 sweeping a small region repeatedly, and both ribbons of the flare on October 26 moved along the same direction instead of separating from each other. These irregular movements also imply that the corresponding flare loops are complex, e.g., several sets of flare loops are twisted together. Although previous studies have suggested that the background magnetic fields prevent confined flares from erupting,based on these observations, we suggest that complex flare loop structures may be responsible for these confined flares.

  19. Regular variation on measure chains

    Czech Academy of Sciences Publication Activity Database

    Řehák, Pavel; Vitovec, J.

    2010-01-01

    Roč. 72, č. 1 (2010), s. 439-448 ISSN 0362-546X R&D Projects: GA AV ČR KJB100190701 Institutional research plan: CEZ:AV0Z10190503 Keywords : regularly varying function * regularly varying sequence * measure chain * time scale * embedding theorem * representation theorem * second order dynamic equation * asymptotic properties Subject RIV: BA - General Mathematics Impact factor: 1.279, year: 2010 http://www.sciencedirect.com/science/article/pii/S0362546X09008475

  20. Manifold Regularized Correlation Object Tracking

    OpenAIRE

    Hu, Hongwei; Ma, Bo; Shen, Jianbing; Shao, Ling

    2017-01-01

    In this paper, we propose a manifold regularized correlation tracking method with augmented samples. To make better use of the unlabeled data and the manifold structure of the sample space, a manifold regularization-based correlation filter is introduced, which aims to assign similar labels to neighbor samples. Meanwhile, the regression model is learned by exploiting the block-circulant structure of matrices resulting from the augmented translated samples over multiple base samples cropped fr...

  1. On geodesics in low regularity

    Science.gov (United States)

    Sämann, Clemens; Steinbauer, Roland

    2018-02-01

    We consider geodesics in both Riemannian and Lorentzian manifolds with metrics of low regularity. We discuss existence of extremal curves for continuous metrics and present several old and new examples that highlight their subtle interrelation with solutions of the geodesic equations. Then we turn to the initial value problem for geodesics for locally Lipschitz continuous metrics and generalize recent results on existence, regularity and uniqueness of solutions in the sense of Filippov.

  2. HLA Class I and Class II Alleles and Haplotypes Confirm the Berber Origin of the Present Day Tunisian Population.

    Directory of Open Access Journals (Sweden)

    Abdelhafidh Hajjej

    Full Text Available In view of its distinct geographical location and relatively small area, Tunisia witnessed the presence of many civilizations and ethnic groups throughout history, thereby questioning the origin of present-day Tunisian population. We investigated HLA class I and class II gene profiles in Tunisians, and compared this profile with those of Mediterranean and Sub-Sahara African populations. A total of 376 unrelated Tunisian individuals of both genders were genotyped for HLA class I (A, B and class II (DRB1, DQB1, using reverse dot-blot hybridization (PCR-SSO method. Statistical analysis was performed using Arlequin software. Phylogenetic trees were constructed by DISPAN software, and correspondence analysis was carried out by VISTA software. One hundred fifty-three HLA alleles were identified in the studied sample, which comprised 41, 50, 40 and 22 alleles at HLA-A,-B,-DRB1 and -DQB1 loci, respectively. The most frequent alleles were HLA-A*02:01 (16.76%, HLA-B*44:02/03 (17.82%, HLA-DRB1*07:01 (19.02%, and HLA-DQB1*03:01 (17.95%. Four-locus haplotype analysis identified HLA-A*02:01-B*50:01-DRB1*07:01-DQB1*02:02 (2.2% as the common haplotype in Tunisians. Compared to other nearby populations, Tunisians appear to be genetically related to Western Mediterranean population, in particular North Africans and Berbers. In conclusion, HLA genotype results indicate that Tunisians are related to present-day North Africans, Berbers and to Iberians, but not to Eastern Arabs (Palestinians, Jordanians and Lebanese. This suggests that the genetic contribution of Arab invasion of 7th-11th century A.D. had little impact of the North African gene pool.

  3. Large-Scale Off-Target Identification Using Fast and Accurate Dual Regularized One-Class Collaborative Filtering and Its Application to Drug Repurposing.

    Directory of Open Access Journals (Sweden)

    Hansaim Lim

    2016-10-01

    Full Text Available Target-based screening is one of the major approaches in drug discovery. Besides the intended target, unexpected drug off-target interactions often occur, and many of them have not been recognized and characterized. The off-target interactions can be responsible for either therapeutic or side effects. Thus, identifying the genome-wide off-targets of lead compounds or existing drugs will be critical for designing effective and safe drugs, and providing new opportunities for drug repurposing. Although many computational methods have been developed to predict drug-target interactions, they are either less accurate than the one that we are proposing here or computationally too intensive, thereby limiting their capability for large-scale off-target identification. In addition, the performances of most machine learning based algorithms have been mainly evaluated to predict off-target interactions in the same gene family for hundreds of chemicals. It is not clear how these algorithms perform in terms of detecting off-targets across gene families on a proteome scale. Here, we are presenting a fast and accurate off-target prediction method, REMAP, which is based on a dual regularized one-class collaborative filtering algorithm, to explore continuous chemical space, protein space, and their interactome on a large scale. When tested in a reliable, extensive, and cross-gene family benchmark, REMAP outperforms the state-of-the-art methods. Furthermore, REMAP is highly scalable. It can screen a dataset of 200 thousands chemicals against 20 thousands proteins within 2 hours. Using the reconstructed genome-wide target profile as the fingerprint of a chemical compound, we predicted that seven FDA-approved drugs can be repurposed as novel anti-cancer therapies. The anti-cancer activity of six of them is supported by experimental evidences. Thus, REMAP is a valuable addition to the existing in silico toolbox for drug target identification, drug repurposing

  4. Large-Scale Off-Target Identification Using Fast and Accurate Dual Regularized One-Class Collaborative Filtering and Its Application to Drug Repurposing.

    Science.gov (United States)

    Lim, Hansaim; Poleksic, Aleksandar; Yao, Yuan; Tong, Hanghang; He, Di; Zhuang, Luke; Meng, Patrick; Xie, Lei

    2016-10-01

    Target-based screening is one of the major approaches in drug discovery. Besides the intended target, unexpected drug off-target interactions often occur, and many of them have not been recognized and characterized. The off-target interactions can be responsible for either therapeutic or side effects. Thus, identifying the genome-wide off-targets of lead compounds or existing drugs will be critical for designing effective and safe drugs, and providing new opportunities for drug repurposing. Although many computational methods have been developed to predict drug-target interactions, they are either less accurate than the one that we are proposing here or computationally too intensive, thereby limiting their capability for large-scale off-target identification. In addition, the performances of most machine learning based algorithms have been mainly evaluated to predict off-target interactions in the same gene family for hundreds of chemicals. It is not clear how these algorithms perform in terms of detecting off-targets across gene families on a proteome scale. Here, we are presenting a fast and accurate off-target prediction method, REMAP, which is based on a dual regularized one-class collaborative filtering algorithm, to explore continuous chemical space, protein space, and their interactome on a large scale. When tested in a reliable, extensive, and cross-gene family benchmark, REMAP outperforms the state-of-the-art methods. Furthermore, REMAP is highly scalable. It can screen a dataset of 200 thousands chemicals against 20 thousands proteins within 2 hours. Using the reconstructed genome-wide target profile as the fingerprint of a chemical compound, we predicted that seven FDA-approved drugs can be repurposed as novel anti-cancer therapies. The anti-cancer activity of six of them is supported by experimental evidences. Thus, REMAP is a valuable addition to the existing in silico toolbox for drug target identification, drug repurposing, phenotypic screening, and

  5. Educational and social class assortative mating in fertile British couples.

    Science.gov (United States)

    Krzyżanowska, Monika; Mascie-Taylor, C G Nicholas

    2014-01-01

    Positive assortative mating for education and social position has been widely reported in a number of countries, but very few studies have tested whether or not educational or social class homogamy is related to differential fertility. This study examined the relationship between educational and social class assortative mating and fertility in a British national cohort. The analyses were based on 7452 husband-wife pairs from the British National Child Development Study (NCDS). The mean fertility was 3.22 children per couple; the number of children significantly increased from higher to lower social classes and from the more educated to the less educated. The extent of assortative mating for social class and educational level was related to fertility; as educational assortative mating decreased so did the average number of children, whereas the opposite trend was observed for social class. When assortative mating for education and social class were considered together, educational assortative mating was the more significant predictor of the number of children and educationally homogamous couples had higher fertility independent of their social class assortative mating. The relationship between assortative mating and fertility for education and social class appeared to be acting in the opposite direction.

  6. The btp [2,6-bis(1,2,3-triazol-4-yl)pyridine] binding motif: a new versatile terdentate ligand for supramolecular and coordination chemistry.

    Science.gov (United States)

    Byrne, Joseph P; Kitchen, Jonathan A; Gunnlaugsson, Thorfinnur

    2014-08-07

    Ligands containing the btp [2,6-bis(1,2,3-triazol-4-yl)pyridine] motif have appeared with increasing regularity over the last decade. This class of ligands, formed in a one pot ‘click’ reaction, has been studied for various purposes, such as for generating d and f metal coordination complexes and supramolecular self-assemblies, and in the formation of dendritic and polymeric networks, etc. This review article introduces btp as a novel and highly versatile terdentate building block with huge potential in inorganic supramolecular chemistry. We will focus on the coordination chemistry of btp ligands with a wide range of metals, and how it compares with other classical pyridyl and polypyridyl based ligands, and then present a selection of applications including use in catalysis, enzyme inhibition, photochemistry, molecular logic and materials, e.g. polymers, dendrimers and gels. The photovoltaic potential of triazolium derivatives of btp and its interactions with anions will also be discussed.

  7. Manifold Regularized Reinforcement Learning.

    Science.gov (United States)

    Li, Hongliang; Liu, Derong; Wang, Ding

    2018-04-01

    This paper introduces a novel manifold regularized reinforcement learning scheme for continuous Markov decision processes. Smooth feature representations for value function approximation can be automatically learned using the unsupervised manifold regularization method. The learned features are data-driven, and can be adapted to the geometry of the state space. Furthermore, the scheme provides a direct basis representation extension for novel samples during policy learning and control. The performance of the proposed scheme is evaluated on two benchmark control tasks, i.e., the inverted pendulum and the energy storage problem. Simulation results illustrate the concepts of the proposed scheme and show that it can obtain excellent performance.

  8. Effects of Regular Classes in Outdoor Education Settings: A Systematic Review on Students’ Learning, Social and Health Dimensions

    Science.gov (United States)

    Becker, Christoph; Lauterbach, Gabriele; Spengler, Sarah; Dettweiler, Ulrich; Mess, Filip

    2017-01-01

    Background: Participants in Outdoor Education Programmes (OEPs) presumably benefit from these programmes in terms of their social and personal development, academic achievement and physical activity (PA). The aim of this systematic review was to identify studies about regular compulsory school- and curriculum-based OEPs, to categorise and evaluate reported outcomes, to assess the methodological quality, and to discuss possible benefits for students. Methods: We searched online databases to identify English- and German-language peer-reviewed journal articles that reported any outcomes on a student level. Two independent reviewers screened studies identified for eligibility and assessed the methodological quality. Results: Thirteen studies were included for analysis. Most studies used a case-study design, the average number of participants was moderate (mean valued (M) = 62.17; standard deviation (SD) = 64.12), and the methodological quality was moderate on average for qualitative studies (M = 0.52; SD = 0.11), and low on average for quantitative studies (M = 0.18; SD = 0.42). Eight studies described outcomes in terms of social dimensions, seven studies in learning dimensions and four studies were subsumed under additional outcomes, i.e., PA and health. Eleven studies reported positive, one study positive as well as negative, and one study reported negative effects. PA and mental health as outcomes were underrepresented. Conclusion: Tendencies were detected that regular compulsory school- and curriculum-based OEPs can promote students in respect of social, academic, physical and psychological dimensions. Very little is known concerning students’ PA or mental health. We recommend conducting more quasi-experimental design and longitudinal studies with a greater number of participants, and a high methodological quality to further investigate these tendencies. PMID:28475167

  9. Effects of Regular Classes in Outdoor Education Settings: A Systematic Review on Students' Learning, Social and Health Dimensions.

    Science.gov (United States)

    Becker, Christoph; Lauterbach, Gabriele; Spengler, Sarah; Dettweiler, Ulrich; Mess, Filip

    2017-05-05

    Participants in Outdoor Education Programmes (OEPs) presumably benefit from these programmes in terms of their social and personal development, academic achievement and physical activity (PA). The aim of this systematic review was to identify studies about regular compulsory school- and curriculum-based OEPs, to categorise and evaluate reported outcomes, to assess the methodological quality, and to discuss possible benefits for students. We searched online databases to identify English- and German-language peer-reviewed journal articles that reported any outcomes on a student level. Two independent reviewers screened studies identified for eligibility and assessed the methodological quality. Thirteen studies were included for analysis. Most studies used a case-study design, the average number of participants was moderate (mean valued (M) = 62.17; standard deviation (SD) = 64.12), and the methodological quality was moderate on average for qualitative studies (M = 0.52; SD = 0.11), and low on average for quantitative studies (M = 0.18; SD = 0.42). Eight studies described outcomes in terms of social dimensions, seven studies in learning dimensions and four studies were subsumed under additional outcomes, i.e., PA and health. Eleven studies reported positive, one study positive as well as negative, and one study reported negative effects. PA and mental health as outcomes were underrepresented. Tendencies were detected that regular compulsory school- and curriculum-based OEPs can promote students in respect of social, academic, physical and psychological dimensions. Very little is known concerning students' PA or mental health. We recommend conducting more quasi-experimental design and longitudinal studies with a greater number of participants, and a high methodological quality to further investigate these tendencies.

  10. Study of a class of hybrid-time systems

    Energy Technology Data Exchange (ETDEWEB)

    Cervantes, I. [Seccion de Estudios de Posgrado e Investigacion, Escuela Superior de Ingenieria Mecanica y Electrica-Culhuacan-IPN, Av. San Ana 1000 Col. San Fco. Culhuacan, Mexico D.F. 04430 (Mexico) and Insituto Potosino de Investigacion Cientifica y Tecnologica (IPICyT), Departamento de Matematicas Aplicadas y Sistemas Computacionales, Camino a la Presa San Jose 2055, Col. Lomas 4a, seccion C.P. 78216, San Luis Potosi, San Luis Potosi (Mexico)]. E-mail: ilse@calmecac.esimecu.ipn.mx; Femat, R. [Insituto Potosino de Investigacion Cientifica y Tecnologica (IPICyT), Departamento de Matematicas Aplicadas y Sistemas Computacionales, Camino a la Presa San Jose 2055, Col. Lomas 4a, seccion C.P. 78216, San Luis Potosi, San Luis Potosi (Mexico); Leyva-Ramos, J. [Insituto Potosino de Investigacion Cientifica y Tecnologica (IPICyT), Departamento de Matematicas Aplicadas y Sistemas Computacionales, Camino a la Presa San Jose 2055, Col. Lomas 4a, seccion C.P. 78216, San Luis Potosi, San Luis Potosi (Mexico)

    2007-05-15

    The aim of this paper is to study the dynamic behavior of a class of hybrid-time systems. In particular, we concern about switched systems constituted by two linear second order systems with a time varying (sinusoidal type) translation term. By means of numerical simulations, system behavior and its relation to system parameters are studied. It is shown that system eigenvalues play a crucial role in the time evolution of the system leading either to regular behavior, oscillatory patterns or intermittent erratic-periodic behavior. Furthermore, it is shown that under certain conditions, presumable fractal structures can be obtained.

  11. Study of a class of hybrid-time systems

    International Nuclear Information System (INIS)

    Cervantes, I.; Femat, R.; Leyva-Ramos, J.

    2007-01-01

    The aim of this paper is to study the dynamic behavior of a class of hybrid-time systems. In particular, we concern about switched systems constituted by two linear second order systems with a time varying (sinusoidal type) translation term. By means of numerical simulations, system behavior and its relation to system parameters are studied. It is shown that system eigenvalues play a crucial role in the time evolution of the system leading either to regular behavior, oscillatory patterns or intermittent erratic-periodic behavior. Furthermore, it is shown that under certain conditions, presumable fractal structures can be obtained

  12. Pupils with sensory disabilities in physical education classes: Attitudes and preferences

    Directory of Open Access Journals (Sweden)

    Petra Kurková

    2015-09-01

    Full Text Available Background: The key factor that affects the success of shaping positive attitudes towards regular life-long performance of physical activity (PA is the pupils' level of inner motivation. This is influenced, among other things, by their family background, the educational institution that they attend and the educator's competencies. Objective: The purpose of this study was to describe and analyse the attitudes among pupils with sensory disabilities in physical education (PE classes. A partial objective was to compare the preferences for various PA by pupils with sensory disabilities in PE classes. Method: A non-standardized questionnaire was used to collect the data. The sample was based on the following features: a a participant had to be deaf or hard of hearing, b a participant had to have a visual disability, and c had to have been educated in special educational settings. The data were quantified on the percentage basis. To carry out cross-group statistical testing of differences, a ratio analysis with the help of the Chi-square test was applied. The level of statistical significance was set to p < .05. We analysed the data of 70 pupils attending the second stage of two elementary schools in Slovakia: a 37 pupils (22 boys and 15 girls, age 13.3 ± 1.45 years from a school for the deaf, and b 33 pupils (14 boys and 19 girls, age 13.4 ± 1.41 years from a school for the blind. Results: The differences in the preferences for various PA during PE classes in the cross-group comparison of pupils with sensory disabilities were discovered. A comparison of the opinions of pupils with sensory disabilities pointed out a difference consisting in a higher percentage of positive attitudes among pupils with visual disabilities in indicators of popularity, importance, the pupils' efforts and feelings towards education. A statistically significant difference was discovered only in feelings during PE classes. This result may be considered

  13. Behavior of physiological variables during a water gymnastics class in women

    Directory of Open Access Journals (Sweden)

    Mabel Micheline Olkoski

    2010-01-01

    Full Text Available The aim of this study was to analyze the behavior of physiological variables and rating of perceived exertion (RPE during the different phases of a water gymnastics class. Seventeen female university students (age: 23 ± 3.5 years were evaluated in two steps: 1 incremental treadmill test (peak VO2 and HRmax; 2 assessment of body composition and achievement in the water gymnastics class (HR, VO2, [lac], and RPE. Descriptive statistics and repeated measures ANOVA with the post hoc Student-Newman-Keuls were used (p< 0.05. The results showed that both HR and VO2 differed significantly (p=0.000 between the three phases of the class. Blood lactate only differed significantly (p=0.001 between the early (1.55 mM and the main phase (3.58 mM. The mean RPE was 11 and total calorie expenditure was 262.10 kcal. In conclusion, the physiological variables studied and RPE vary significantly according to the phase of the water gymnastics class. In addition, the intensity of effort (HR, VO2 and [lac] obtained for the main phase is within the parameters established in the literature for aerobic exercise. Thus, regular water gymnastics classes with this structure may improve the physical condition of young adult women.

  14. Laplacian manifold regularization method for fluorescence molecular tomography

    Science.gov (United States)

    He, Xuelei; Wang, Xiaodong; Yi, Huangjian; Chen, Yanrong; Zhang, Xu; Yu, Jingjing; He, Xiaowei

    2017-04-01

    Sparse regularization methods have been widely used in fluorescence molecular tomography (FMT) for stable three-dimensional reconstruction. Generally, ℓ1-regularization-based methods allow for utilizing the sparsity nature of the target distribution. However, in addition to sparsity, the spatial structure information should be exploited as well. A joint ℓ1 and Laplacian manifold regularization model is proposed to improve the reconstruction performance, and two algorithms (with and without Barzilai-Borwein strategy) are presented to solve the regularization model. Numerical studies and in vivo experiment demonstrate that the proposed Gradient projection-resolved Laplacian manifold regularization method for the joint model performed better than the comparative algorithm for ℓ1 minimization method in both spatial aggregation and location accuracy.

  15. Learning Sparse Visual Representations with Leaky Capped Norm Regularizers

    OpenAIRE

    Wangni, Jianqiao; Lin, Dahua

    2017-01-01

    Sparsity inducing regularization is an important part for learning over-complete visual representations. Despite the popularity of $\\ell_1$ regularization, in this paper, we investigate the usage of non-convex regularizations in this problem. Our contribution consists of three parts. First, we propose the leaky capped norm regularization (LCNR), which allows model weights below a certain threshold to be regularized more strongly as opposed to those above, therefore imposes strong sparsity and...

  16. Adaptive regularization of noisy linear inverse problems

    DEFF Research Database (Denmark)

    Hansen, Lars Kai; Madsen, Kristoffer Hougaard; Lehn-Schiøler, Tue

    2006-01-01

    In the Bayesian modeling framework there is a close relation between regularization and the prior distribution over parameters. For prior distributions in the exponential family, we show that the optimal hyper-parameter, i.e., the optimal strength of regularization, satisfies a simple relation: T......: The expectation of the regularization function, i.e., takes the same value in the posterior and prior distribution. We present three examples: two simulations, and application in fMRI neuroimaging....

  17. 26 CFR 31.3211-3 - Employee representative supplemental tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Employee representative supplemental tax. 31... (CONTINUED) EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE Railroad Retirement Tax Act (Chapter 22, Internal Revenue Code of 1954) Tax on Employee...

  18. Exclusion of children with intellectual disabilities from regular ...

    African Journals Online (AJOL)

    Study investigated why teachers exclude children with intellectual disability from the regular classrooms in Nigeria. Participants were, 169 regular teachers randomly selected from Oyo and Ogun states. Questionnaire was used to collect data result revealed that 57.4% regular teachers could not cope with children with ID ...

  19. On infinite regular and chiral maps

    OpenAIRE

    Arredondo, John A.; Valdez, Camilo Ramírez y Ferrán

    2015-01-01

    We prove that infinite regular and chiral maps take place on surfaces with at most one end. Moreover, we prove that an infinite regular or chiral map on an orientable surface with genus can only be realized on the Loch Ness monster, that is, the topological surface of infinite genus with one end.

  20. 29 CFR 779.18 - Regular rate.

    Science.gov (United States)

    2010-07-01

    ... employee under subsection (a) or in excess of the employee's normal working hours or regular working hours... Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR... not less than one and one-half times their regular rates of pay. Section 7(e) of the Act defines...

  1. BIOASSAY STUDIES OF METAL(II) COMPLEXES OF 2,2'-(ETHANE ...

    African Journals Online (AJOL)

    Preferred Customer

    diyldiimino)diacetic acid (EDDA) were prepared and characterized. Coordination complexes of the EDDA ... corresponding amines with alkyl halide to bear diammines of the same class with different substituents. ... Bioassay studies of metal(II) complexes of 2,2'-(ethane-1,2-diyldiimino)diacetic acid. Bull. Chem. Soc. Ethiop.

  2. Singular pontentials and analytic regularization in classical Yang-Mills equations

    International Nuclear Information System (INIS)

    Bollini, C.G.; Giambiagi, J.J.; Tiomno, J.

    1978-11-01

    The class of instanton solutions with 'extension' parameter lambda 2 positive is extended to lambda 2 negative. The nature of the singular sphere of radius 'lambda' is analized in the light of the analytical regularization method. This leads to well defined solutions of the Yang-Mills equations. Some of them are sourceless ('+-io' and 'Vp'), others correspond to currents concentrated on the sphere of singularity ('+' and '-'). Although the equations are non-linear, the 'Vp' solution turns out to be real part of the '+-io' solutions. The anzats of t'Hooft for the superposition of instantons is used to sum the contributions corresponding to lambda 2 with positive and negative signs. A subsequent limiting process allows then the construction of solutions of the 'multipole' type. The general situation of potentials having a denominator D, with a corresponding surface of singularity at D=0, is also considered in the same light [pt

  3. Continuum regularized Yang-Mills theory

    International Nuclear Information System (INIS)

    Sadun, L.A.

    1987-01-01

    Using the machinery of stochastic quantization, Z. Bern, M. B. Halpern, C. Taubes and I recently proposed a continuum regularization technique for quantum field theory. This regularization may be implemented by applying a regulator to either the (d + 1)-dimensional Parisi-Wu Langevin equation or, equivalently, to the d-dimensional second order Schwinger-Dyson (SD) equations. This technique is non-perturbative, respects all gauge and Lorentz symmetries, and is consistent with a ghost-free gauge fixing (Zwanziger's). This thesis is a detailed study of this regulator, and of regularized Yang-Mills theory, using both perturbative and non-perturbative techniques. The perturbative analysis comes first. The mechanism of stochastic quantization is reviewed, and a perturbative expansion based on second-order SD equations is developed. A diagrammatic method (SD diagrams) for evaluating terms of this expansion is developed. We apply the continuum regulator to a scalar field theory. Using SD diagrams, we show that all Green functions can be rendered finite to all orders in perturbation theory. Even non-renormalizable theories can be regularized. The continuum regulator is then applied to Yang-Mills theory, in conjunction with Zwanziger's gauge fixing. A perturbative expansion of the regulator is incorporated into the diagrammatic method. It is hoped that the techniques discussed in this thesis will contribute to the construction of a renormalized Yang-Mills theory is 3 and 4 dimensions

  4. Comparison of energy expenditure and heart rate responses between three commercial group fitness classes.

    Science.gov (United States)

    Wickham, James B; Mullen, Nicholas J; Whyte, Douglas G; Cannon, Jack

    2017-07-01

    The objectives of this study were to compare the energy expenditure and heart rate responses between three commercial group fitness classes (group resistance exercise [PUMP]; indoor stationary cycling [RIDE]; and step aerobics [STEP]). One-Way Repeated Measures incorporating a Latin Square Design for class randomisation. Ten participants (5 males and 5 females) completed each group fitness class in random order with energy expenditure and heart rate determined using an Actiheart monitor. STEP and RIDE produced significantly (pheart rates (HR avg ) (85.8±5.1% and 86.4±4.3% of HR max , respectively) compared to PUMP (73.7±7% of HR max ). HR peak was also significantly (pexpenditure (TEE), both absolute and relative, were significantly (pexpenditure was highly comparable between RIDE and STEP, which suggests these group fitness classes are more effective for developing cardiovascular fitness and assisting with weight management compared with group resistance exercise classes when performed on a regular basis. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  5. Divergent Synthesis of Solanidine and 22-epi-Solanidine.

    Science.gov (United States)

    Hou, Ling-Li; Shi, Yong; Zhang, Zhi-Dan; Wu, Jing-Jing; Yang, Qing-Xiong; Tian, Wei-Sheng

    2017-07-21

    A divergent synthesis of solanidine and 22-epi-solanidine, two 25S natural steroidal alkaloids, from 25R-configured diosgenin acetate, is described. Initially, solanidine was synthesized through a series of transformations including a cascade ring-switching process of furostan-26-acid, an epimerization of C25 controlled by the conformation of six-membered lactone ring, an intramolecular Schmidt reaction, and an imine reduction/intramolecular aminolysis process. To address the epimerization issue during Schmidt reaction, an improved synthesis was developed, which also led to a synthesis of 22-epi-solanidine. In this synthesis, selective transformation of azido lactone to azido diol and amino diol was realized through a reduction relay tactic. The azido diol was transformed to solanidine via an intramolecular Schmidt reaction/N-alkylation/reduction process and to 22-epi-solanidine via an intramolecular double N-alkylation process.

  6. Regularity effect in prospective memory during aging

    OpenAIRE

    Blondelle, Geoffrey; Hainselin, Mathieu; Gounden, Yannick; Heurley, Laurent; Voisin, Hélène; Megalakaki, Olga; Bressous, Estelle; Quaglino, Véronique

    2016-01-01

    Background: Regularity effect can affect performance in prospective memory (PM), but little is known on the cognitive processes linked to this effect. Moreover, its impacts with regard to aging remain unknown. To our knowledge, this study is the first to examine regularity effect in PM in a lifespan perspective, with a sample of young, intermediate, and older adults.Objective and design: Our study examined the regularity effect in PM in three groups of participants: 28 young adults (18–30), 1...

  7. 20 CFR 226.14 - Employee regular annuity rate.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Employee regular annuity rate. 226.14 Section... COMPUTING EMPLOYEE, SPOUSE, AND DIVORCED SPOUSE ANNUITIES Computing an Employee Annuity § 226.14 Employee regular annuity rate. The regular annuity rate payable to the employee is the total of the employee tier I...

  8. 39 CFR 6.1 - Regular meetings, annual meeting.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Regular meetings, annual meeting. 6.1 Section 6.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE MEETINGS (ARTICLE VI) § 6.1 Regular meetings, annual meeting. The Board shall meet regularly on a schedule...

  9. Pain patterns during adolescence can be grouped into four pain classes with distinct profiles

    DEFF Research Database (Denmark)

    Holden, Sinead; Rathleff, Michael Skovdal; Roos, E. M.

    2018-01-01

    L (assessed by Euro-QoL 5D-3L). Latent class analysis was used to classify spatial pain patterns, based on the pain sites. The analysis included 2953 adolescents. RESULTS: Four classes were identified as follows: (1) little or no pain (63% of adolescents), (2) majority lower extremity pain (10%), (3) multi......-site bodily pain (22%) and (4) head and stomach pain (3%). The lower extremity multi-site pain group reported highest weekly sports participation (p ....001). Males were more likely to belong to the little or no pain class, whereas females were more likely to belong to the multi-site bodily pain class. CONCLUSIONS: Latent class analysis identified distinct classes of pain patterns in adolescents, characterized by sex, differences in HRQoL and sports...

  10. Radioactive fallout collected in Tokyo on November 26, 1955

    Energy Technology Data Exchange (ETDEWEB)

    Sugiura, Y; Kanazawa, T

    1956-01-01

    A large nuclear weapon test by Russia was reported November 23, 1955 as having occurred the previous day. Rain water and fallout samples taken in Tokyo before and after the 22nd indicated the test had produced a secondary fallout from some previous explosion. Rain water of the 21st and fallout of the 29th had radioactive content of 13 days half-life; fallout of the 26th, rain of the 27th 3 days half-life. Sample of the 26th consisted of 15 mg of sooty material giving nearly 2000 counts/min at that time.

  11. Meta-analysis of the Effectiveness of Educational and Therapeutic Interventions on the Four Classes of Learning Disorders

    Directory of Open Access Journals (Sweden)

    Javad Mesrabadi

    2018-04-01

    Full Text Available Abstract Background: Learning disorders is one of the most common problems of students, which attracted the attention of many psychologists and many studies have been conducted on the effectiveness of various interventions on different classes of learning disorder. The present study aimed to conclude general conclusions about the effectiveness of various educational and therapeutic interventions and the discovery of possible moderating variables. Materials and Methods: In order to achieve the research purpose by using meta-analysis method, quantitative results of 128 selected researches which were obtained according to the criteria for entering and leaving and using keywords were used. In total, 623 primary effect sizes were obtained and analyzed by using CMA2 software. Results: The results of the analysis showed that amount of combined effect size of the educational and therapeutic interventions on learning disorders was 1.13, and after dividing into multiple predecessor and consequence variables, the amounts of the combined effect size for educational interventions and therapeutic interventions for overall class of learning disabilities were respectively 0.74 and 1.26, for reading disorder 0.87 and 1.01, for writing disorder 1.20 and 1.22, and for mathematical disorder 1.29 and 1.26 that all of these effects size were significant (p≤0.001. Also, the results of independent t-test showed that the difference in the effectiveness of therapeutic interventions on reading disorder and educational interventions on mathematical disorder is significant (p≤0.001. Conclusion: Based on the size of the effects obtained, it can be said that educational and therapeutic interventions have a very high effect on learning disabilities, and the use of therapeutic interventions for reading disorder and educational interventions for mathematical disorder is more effective.

  12. A regularized stationary mean-field game

    KAUST Repository

    Yang, Xianjin

    2016-01-01

    In the thesis, we discuss the existence and numerical approximations of solutions of a regularized mean-field game with a low-order regularization. In the first part, we prove a priori estimates and use the continuation method to obtain the existence of a solution with a positive density. Finally, we introduce the monotone flow method and solve the system numerically.

  13. A regularized stationary mean-field game

    KAUST Repository

    Yang, Xianjin

    2016-04-19

    In the thesis, we discuss the existence and numerical approximations of solutions of a regularized mean-field game with a low-order regularization. In the first part, we prove a priori estimates and use the continuation method to obtain the existence of a solution with a positive density. Finally, we introduce the monotone flow method and solve the system numerically.

  14. Automating InDesign with Regular Expressions

    CERN Document Server

    Kahrel, Peter

    2006-01-01

    If you need to make automated changes to InDesign documents beyond what basic search and replace can handle, you need regular expressions, and a bit of scripting to make them work. This Short Cut explains both how to write regular expressions, so you can find and replace the right things, and how to use them in InDesign specifically.

  15. Convective removal of the Tibetan Plateau mantle lithosphere by 26 Ma

    Science.gov (United States)

    Lu, Haijian; Tian, Xiaobo; Yun, Kun; Li, Haibing

    2018-04-01

    During the late Oligocene-early Miocene there were several major geological events in and around the Tibetan Plateau (TP). First, crustal shortening deformation ceased completely within the TP before 25 Ma and instead adakitic rocks and potassic-ultrapotassic volcanics were emplaced in the Lhasa terrane since 26-25 Ma. Several recent paleoelevation reconstructions suggest an Oligocene-early Miocene uplift of 1500-3000 m for the Qiangtang (QT) and Songpan-Ganzi (SG) terranes, although the exact timing is unclear. As a possible response to this uplift, significant desertification occurred in the vicinity of the TP at 26-22 Ma, and convergence between India and Eurasia slowed considerably at 26-20 Ma. Subsequently, E-W extension was initiated no later than 18 Ma in the Lhasa and QT terranes. In contrast, the tectonic deformation around the TP was dominated by radial expansion of shortening deformation since 25-22 Ma. The plateau-wide near-synchroneity of these events calls for an internally consistent model which can be best described as convective removal of the lower mantle lithosphere. Geophysical and petrochemical evidence further confirms that this extensive removal occurred beneath the QT and SG terranes. The present review concludes that, other than plate boundary stress, the internal stress within the TP lithosphere could have contributed to rapid wholesale uplift and a series of concomitant tectonic events, accompanied by major aridification, since 26 Ma.

  16. Social class variation in medicine use among adolescents

    DEFF Research Database (Denmark)

    Holstein, Bjørn E; Hansen, Ebba Holme; Due, Pernille

    2004-01-01

    BACKGROUND: Little is known about social determinants of adolescents' medicine use. The objective was to analyse the association between the family's social class and adolescents' use of medicine for headache, stomachache, difficulties in getting to sleep, and nervousness. METHODS: Cross......, participation rate 88%, n=5,205. RESULTS: Logistic regression analyses showed that medicine use for all four symptoms increased by decreasing social class, controlled for age and prevalence of the specific symptom for which the medicine was taken. Adjusted OR (95% CI) for medicine use among students from lower...... social classes were: medicine for headache 1.35 (1.11-1.65), medicine for stomachache 1.41 (1.08-1.84), medicine for difficulties in getting to sleep 2.00 (1.30-3.08), and medicine for nervousness 3.22 (1.87-5.56). CONCLUSION: Symptom-adjusted medicine use in a representative sample of Danish adolescents...

  17. Biderivations of W-algebra $W(2,2)$ and Virasoro algebra without skewsymmetric condition and their applications

    OpenAIRE

    Tang, Xiaomin

    2016-01-01

    In this paper, we characterize the biderivations of W-algebra $W(2,2)$ and Virasoro algebra $Vir$ without skewsymmetric condition. We get two classes of non-inner biderivations. As applications, we also get the forms of linear commuting maps on W-algebra $W(2,2)$ and Virasoro algebra $Vir$.

  18. 26 CFR 31.3221-4 - Exception from supplemental tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Exception from supplemental tax. 31.3221-4...) EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE Railroad Retirement Tax Act (Chapter 22, Internal Revenue Code of 1954) Tax on Employers § 31.3221...

  19. Optimal behaviour can violate the principle of regularity.

    Science.gov (United States)

    Trimmer, Pete C

    2013-07-22

    Understanding decisions is a fundamental aim of behavioural ecology, psychology and economics. The regularity axiom of utility theory holds that a preference between options should be maintained when other options are made available. Empirical studies have shown that animals violate regularity but this has not been understood from a theoretical perspective, such decisions have therefore been labelled as irrational. Here, I use models of state-dependent behaviour to demonstrate that choices can violate regularity even when behavioural strategies are optimal. I also show that the range of conditions over which regularity should be violated can be larger when options do not always persist into the future. Consequently, utility theory--based on axioms, including transitivity, regularity and the independence of irrelevant alternatives--is undermined, because even alternatives that are never chosen by an animal (in its current state) can be relevant to a decision.

  20. Dimensional regularization in configuration space

    International Nuclear Information System (INIS)

    Bollini, C.G.; Giambiagi, J.J.

    1995-09-01

    Dimensional regularization is introduced in configuration space by Fourier transforming in D-dimensions the perturbative momentum space Green functions. For this transformation, Bochner theorem is used, no extra parameters, such as those of Feynman or Bogoliubov-Shirkov are needed for convolutions. The regularized causal functions in x-space have ν-dependent moderated singularities at the origin. They can be multiplied together and Fourier transformed (Bochner) without divergence problems. The usual ultraviolet divergences appear as poles of the resultant functions of ν. Several example are discussed. (author). 9 refs

  1. Matrix regularization of 4-manifolds

    OpenAIRE

    Trzetrzelewski, M.

    2012-01-01

    We consider products of two 2-manifolds such as S^2 x S^2, embedded in Euclidean space and show that the corresponding 4-volume preserving diffeomorphism algebra can be approximated by a tensor product SU(N)xSU(N) i.e. functions on a manifold are approximated by the Kronecker product of two SU(N) matrices. A regularization of the 4-sphere is also performed by constructing N^2 x N^2 matrix representations of the 4-algebra (and as a byproduct of the 3-algebra which makes the regularization of S...

  2. Regular Breakfast and Blood Lead Levels among Preschool Children

    Directory of Open Access Journals (Sweden)

    Needleman Herbert

    2011-04-01

    Full Text Available Abstract Background Previous studies have shown that fasting increases lead absorption in the gastrointestinal tract of adults. Regular meals/snacks are recommended as a nutritional intervention for lead poisoning in children, but epidemiological evidence of links between fasting and blood lead levels (B-Pb is rare. The purpose of this study was to examine the association between eating a regular breakfast and B-Pb among children using data from the China Jintan Child Cohort Study. Methods Parents completed a questionnaire regarding children's breakfast-eating habit (regular or not, demographics, and food frequency. Whole blood samples were collected from 1,344 children for the measurements of B-Pb and micronutrients (iron, copper, zinc, calcium, and magnesium. B-Pb and other measures were compared between children with and without regular breakfast. Linear regression modeling was used to evaluate the association between regular breakfast and log-transformed B-Pb. The association between regular breakfast and risk of lead poisoning (B-Pb≥10 μg/dL was examined using logistic regression modeling. Results Median B-Pb among children who ate breakfast regularly and those who did not eat breakfast regularly were 6.1 μg/dL and 7.2 μg/dL, respectively. Eating breakfast was also associated with greater zinc blood levels. Adjusting for other relevant factors, the linear regression model revealed that eating breakfast regularly was significantly associated with lower B-Pb (beta = -0.10 units of log-transformed B-Pb compared with children who did not eat breakfast regularly, p = 0.02. Conclusion The present study provides some initial human data supporting the notion that eating a regular breakfast might reduce B-Pb in young children. To our knowledge, this is the first human study exploring the association between breakfast frequency and B-Pb in young children.

  3. Visual imaging capacity and imagery control in Fine Arts students.

    Science.gov (United States)

    Pérez-Fabello, Maria José; Campos, Alfredo; Gómez-Juncal, Rocío

    2007-06-01

    This study investigated relationships between visual imaging abilities (imaging capacity and imagery control) and academic performance in 146 Fine Arts students (31 men, 115 women). Mean age was 22.3 yr. (SD= 1.9; range 20-26 yr.). All of the participants who volunteered for the experiment regularly attended classes and were first, second, or third year students. For evaluation of imaging abilities, the Spanish versions of the Gordon Test of Visual Imagery Control, the Vividness of Visual Imagery Questionnaire, the Verbalizer-Visualizer Questionnaire, and Betts' Questionnaire Upon Mental Imagery were used. Academic performance was assessed in four areas, Drawing, Painting, Sculpture, and Complementary Subjects, over a three-year period. The results indicate that imagery control was associated with academic performance in Fine Arts. These findings are discussed in the context of previous studies, and new lines of research are proposed.

  4. On the equivalence of different regularization methods

    International Nuclear Information System (INIS)

    Brzezowski, S.

    1985-01-01

    The R-circunflex-operation preceded by the regularization procedure is discussed. Some arguments are given, according to which the results may depend on the method of regularization, introduced in order to avoid divergences in perturbation calculations. 10 refs. (author)

  5. Accreting fluids onto regular black holes via Hamiltonian approach

    Energy Technology Data Exchange (ETDEWEB)

    Jawad, Abdul [COMSATS Institute of Information Technology, Department of Mathematics, Lahore (Pakistan); Shahzad, M.U. [COMSATS Institute of Information Technology, Department of Mathematics, Lahore (Pakistan); University of Central Punjab, CAMS, UCP Business School, Lahore (Pakistan)

    2017-08-15

    We investigate the accretion of test fluids onto regular black holes such as Kehagias-Sfetsos black holes and regular black holes with Dagum distribution function. We analyze the accretion process when different test fluids are falling onto these regular black holes. The accreting fluid is being classified through the equation of state according to the features of regular black holes. The behavior of fluid flow and the existence of sonic points is being checked for these regular black holes. It is noted that the three-velocity depends on critical points and the equation of state parameter on phase space. (orig.)

  6. Manifold regularized discriminative nonnegative matrix factorization with fast gradient descent.

    Science.gov (United States)

    Guan, Naiyang; Tao, Dacheng; Luo, Zhigang; Yuan, Bo

    2011-07-01

    Nonnegative matrix factorization (NMF) has become a popular data-representation method and has been widely used in image processing and pattern-recognition problems. This is because the learned bases can be interpreted as a natural parts-based representation of data and this interpretation is consistent with the psychological intuition of combining parts to form a whole. For practical classification tasks, however, NMF ignores both the local geometry of data and the discriminative information of different classes. In addition, existing research results show that the learned basis is unnecessarily parts-based because there is neither explicit nor implicit constraint to ensure the representation parts-based. In this paper, we introduce the manifold regularization and the margin maximization to NMF and obtain the manifold regularized discriminative NMF (MD-NMF) to overcome the aforementioned problems. The multiplicative update rule (MUR) can be applied to optimizing MD-NMF, but it converges slowly. In this paper, we propose a fast gradient descent (FGD) to optimize MD-NMF. FGD contains a Newton method that searches the optimal step length, and thus, FGD converges much faster than MUR. In addition, FGD includes MUR as a special case and can be applied to optimizing NMF and its variants. For a problem with 165 samples in R(1600), FGD converges in 28 s, while MUR requires 282 s. We also apply FGD in a variant of MD-NMF and experimental results confirm its efficiency. Experimental results on several face image datasets suggest the effectiveness of MD-NMF.

  7. Perceptions of the activity, the social climate, and the self during group exercise classes regulate intrinsic satisfaction.

    Science.gov (United States)

    Maher, Jaclyn P; Gottschall, Jinger S; Conroy, David E

    2015-01-01

    Engaging in regular physical activity is a challenging task for many adults. Intrinsic satisfaction with exercise classes is thought to promote adherence to physical activity. This study examined the characteristics of exercise classes that impact within-person changes in intrinsic satisfaction over the course of an extended group exercise program. A 30-week physical activity trial was conducted with assessments at the end of each class. Community-living adults (n = 29) were instructed to complete at least six group exercise classes each week and, following each exercise class, complete a questionnaire asking about the characteristics of the class and the participant's evaluation of the class. Intrinsic satisfaction was high, on average, but varied as much within-person from class-to-class as it did between exercisers. Participants reported the greatest intrinsic satisfaction when classes placed greater emphasis on exercisers' involvement with the group task, feelings of competence, and encouragement from the instructor. For the most part, exercise classes that were more intense than usual were perceived by exercisers as less intrinsically satisfying. Some overall characteristics of the exercise classes were also associated with intrinsic satisfaction. The social and motivational characteristics of group exercise classes contribute to exercisers' intrinsic satisfaction with classes and attention to those dynamics, as well as the intensity of the exercise, may improve adherence for exercise regimens.

  8. Cosmogenic /sup 22/Na and /sup 26/Al in samples of lunar ground from a drill column of Moon-24

    Energy Technology Data Exchange (ETDEWEB)

    Lavrukhina, A.K.; Povinets, P.; Ustinova, G.K.

    1984-01-01

    The method of low background (..beta..-..gamma..-..gamma..)-spectrometry without destruction of the sample has been used to measure /sup 22/Na and /sup 26/Al radioactivity in samples of lunar ground 24118.4-4, 24143.4-4 apd 24184.4-4 from the ''Luna-24'' drilling column. Equilibrium radioactivity of these cosmogenic isotopes is calculated by the analytic method. The analysis of theoretical and experimental data shows that at depths lower than approximately 40 cm from the lunar surface the drilling process did not bring about ground mixing in the drilling column. For the last million of years the regolite surface layer in the place of ''Luna-24'' landing remained pracically unchanged, i.e. has not been subjected to intensive effect of some mechanic processes on lunar surface. The average intensity of galactic cosmic rays with the rigidity > 0.5 GV for the last million years within the limits of approximtaely 20% remained stable and corresponded to their modern medium intensity 0.24 particlesxcm/sup -2/xc/sup -1/xsr/sup -1/. The average spectrum of galactic cosmic rays for a million years approximately corresponds to the average spectrum for 1962 or 1971.

  9. Traction cytometry: regularization in the Fourier approach and comparisons with finite element method.

    Science.gov (United States)

    Kulkarni, Ankur H; Ghosh, Prasenjit; Seetharaman, Ashwin; Kondaiah, Paturu; Gundiah, Namrata

    2018-05-09

    Traction forces exerted by adherent cells are quantified using displacements of embedded markers on polyacrylamide substrates due to cell contractility. Fourier Transform Traction Cytometry (FTTC) is widely used to calculate tractions but has inherent limitations due to errors in the displacement fields; these are mitigated through a regularization parameter (γ) in the Reg-FTTC method. An alternate finite element (FE) approach computes tractions on a domain using known boundary conditions. Robust verification and recovery studies are lacking but essential in assessing the accuracy and noise sensitivity of the traction solutions from the different methods. We implemented the L2 regularization method and defined a maximum curvature point in the traction with γ plot as the optimal regularization parameter (γ*) in the Reg-FTTC approach. Traction reconstructions using γ* yield accurate values of low and maximum tractions (Tmax) in the presence of up to 5% noise. Reg-FTTC is hence a clear improvement over the FTTC method but is inadequate to reconstruct low stresses such as those at nascent focal adhesions. FE, implemented using a node-by-node comparison, showed an intermediate reconstruction compared to Reg-FTTC. We performed experiments using mouse embryonic fibroblast (MEF) and compared results between these approaches. Tractions from FTTC and FE showed differences of ∼92% and 22% as compared to Reg-FTTC. Selection of an optimum value of γ for each cell reduced variability in the computed tractions as compared to using a single value of γ for all the MEF cells in this study.

  10. Singular potentials and analytic regularization in classical Yang-Mills equations

    International Nuclear Information System (INIS)

    Bollini, C.G.; Giambiagi, J.J.; Tiomno, J.

    1978-10-01

    The class of instanton solutions with 'extension' parameter Λ 2 positive is extended to Λ 2 negative. The nature of the singular sphere of radius |Λ| is analized in the light of the analytical regularization method. This leads to well defined solutions of the Yang - Mills equations. Some of them are sourceless ('+- i o' and 'Vp'), others correspond to currents concentrated on the sphere of singularity ('+' and '-'). Although the equations are non-linear, the 'Vp' solutions turns out to be the real part of the '+- i o' solutions. The anzats of t'Hooft for the superposition of instantons is used to sum the contributions corresponding to Λ 2 with positive and negative signs. A subsequent limiting process allows then the construction of solutions of the 'multipole' type. The general situation of potentials having a denominator D, with a corresponding surface of singularity at D=0, is also considered in the same light. (Author) [pt

  11. Spectra of primordial fluctuations in two-perfect-fluid regular bounces

    International Nuclear Information System (INIS)

    Finelli, Fabio; Peter, Patrick; Pinto-Neto, Nelson

    2008-01-01

    We introduce analytic solutions for a class of two components bouncing models, where the bounce is triggered by a negative energy density perfect fluid. The equation of state of the two components are constant in time, but otherwise unrelated. By numerically integrating regular equations for scalar cosmological perturbations, we find that the (would-be) growing mode of the Newtonian potential before the bounce never matches with the growing mode in the expanding stage. For the particular case of a negative energy density component with a stiff equation of state we give a detailed analytic study, which is in complete agreement with the numerical results. We also perform analytic and numerical calculations for long wavelength tensor perturbations, obtaining that, in most cases of interest, the tensor spectral index is independent of the negative energy fluid and given by the spectral index of the growing mode in the contracting stage. We compare our results with previous investigations in the literature

  12. Bounded Perturbation Regularization for Linear Least Squares Estimation

    KAUST Repository

    Ballal, Tarig

    2017-10-18

    This paper addresses the problem of selecting the regularization parameter for linear least-squares estimation. We propose a new technique called bounded perturbation regularization (BPR). In the proposed BPR method, a perturbation with a bounded norm is allowed into the linear transformation matrix to improve the singular-value structure. Following this, the problem is formulated as a min-max optimization problem. Next, the min-max problem is converted to an equivalent minimization problem to estimate the unknown vector quantity. The solution of the minimization problem is shown to converge to that of the ℓ2 -regularized least squares problem, with the unknown regularizer related to the norm bound of the introduced perturbation through a nonlinear constraint. A procedure is proposed that combines the constraint equation with the mean squared error (MSE) criterion to develop an approximately optimal regularization parameter selection algorithm. Both direct and indirect applications of the proposed method are considered. Comparisons with different Tikhonov regularization parameter selection methods, as well as with other relevant methods, are carried out. Numerical results demonstrate that the proposed method provides significant improvement over state-of-the-art methods.

  13. Regular consumption of a flavanol-rich chocolate can improve oxidant stress in young soccer players.

    Science.gov (United States)

    Fraga, Cesar G; Actis-Goretta, Lucas; Ottaviani, Javier I; Carrasquedo, Fernando; Lotito, Silvina B; Lazarus, Sheryl; Schmitz, Harold H; Keen, Carl L

    2005-03-01

    The consumption of a diet rich in certain flavonoids, including the flavanol sub-class, has been associated with a reduced risk for vascular disease. We evaluated the effects of the regular consumption (14 d) of a flavanol-containing milk chocolate (FCMC) or cocoa butter chocolate (CBC) on variables related to vascular disease risk, oxidative stress and physical activity. Twenty-eight free-living, young (18-20 years old) male soccer players consumed daily 105 g of FCMC (168 mg of flavanols) or CBC (cardiovascular health and oxidant stress. The presence of significant quantities of flavanols in FCMC is likely to have been one of the contributing factors to these results.

  14. Expression, purification and insights into structure and folding of the ADAM22 pro domain

    DEFF Research Database (Denmark)

    Sørensen, Hans Peter; Jacobsen, Jonas; Nielbo, Steen

    2008-01-01

    . To understand the functions of human ADAM pro domains and to determine three-dimensional structures, we have screened promising targets for expression and purification properties when using Escherichia coli as the host. The pro domain of ADAM22 (ADAM22-P) expressed in E. coli was folded, as determined by CD...... and NMR spectroscopy. An ADAM22-P fragment encoding residues 26-199 could be expressed in high amounts, remained soluble above 1 mM, and was suitable for structural studies by NMR spectroscopy. CD spectroscopy and predictions suggest that the secondary structure in ADAM22-P consists of beta...

  15. 26 CFR 31.3221-1 - Measure of employer tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Measure of employer tax. 31.3221-1 Section 31... TAXES AND COLLECTION OF INCOME TAX AT SOURCE EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE Railroad Retirement Tax Act (Chapter 22, Internal Revenue Code of 1954) Tax on Employers § 31.3221-1...

  16. 26 CFR 31.3201-1 - Measure of employee tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Measure of employee tax. 31.3201-1 Section 31... TAXES AND COLLECTION OF INCOME TAX AT SOURCE EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE Railroad Retirement Tax Act (Chapter 22, Internal Revenue Code of 1954) Tax on Employees § 31.3201-1...

  17. Internet-based remote counseling to support stress management: preventing interruptions to regular exercise in elderly people

    Science.gov (United States)

    Hashimoto, Sayuri; Munakata, Tsunestugu; Hashimoto, Nobuyuki; Okunaka, Jyunzo; Koga, Tatsuzo

    2006-01-01

    Our research showed that a high degree of life-stress has a negative mental health effect that may interrupt regular exercise. We used an internet based, remotely conducted, face to face, preventive counseling program using video monitors to reduce the source of life-stresses that interrupts regular exercise and evaluated the preventative effects of the program in elderly people. NTSC Video signals were converted to the IP protocol and facial images were transmitted to a PC display using the exclusive optical network lines of JGN2. Participants were 22 elderly people in Hokkaido, Japan, who regularly played table tennis. A survey was conducted before the intervention in August 2003. IT remote counseling was conducted on two occasions for one hour on each occasion. A post intervention survey was conducted in February 2004 and a follow-up survey was conducted in March 2005. Network quality was satisfactory with little data loss and high display quality. Results indicated that self-esteem increased significantly, trait anxiety decreased significantly, cognition of emotional support by people other than family members had a tendency to increase, and source of stress had a tendency to decrease after the intervention. Follow-up results indicated that cognition of emotional support by family increased significantly, and interpersonal dependency decreased significantly compared to before the intervention. These results suggest that face to face IT remote counseling using video monitors is useful to keep elderly people from feeling anxious and to make them confident to continue exercising regularly. Moreover, it has a stress management effect.

  18. “Veo a los humanos como a árboles”: aproximación exegética al relato de curación del Ciego de Betsaida (Mc 8:22-26

    Directory of Open Access Journals (Sweden)

    Juan Alberto Casas Ramírez

    2017-01-01

    Full Text Available Este artículo propone un análisis exegético del relato bíblico de la curación del ciego de Betsaida (Mc 8:22-26 a partir del desarrollo de tres aproximaciones sucesivas, interdependientes y acumulativas. En primer lugar se aborda la perícopa mediante la presentación de la versión griega, su estructura narrativa y su traducción, de corte literal. En segundo lugar se abordan los contextos narrativos del texto desde su marco literario y narrativo. Finalmente, se analiza cada una de las escenas del relato tratando de dilucidar su sentido simbólico.

  19. MRI reconstruction with joint global regularization and transform learning.

    Science.gov (United States)

    Tanc, A Korhan; Eksioglu, Ender M

    2016-10-01

    Sparsity based regularization has been a popular approach to remedy the measurement scarcity in image reconstruction. Recently, sparsifying transforms learned from image patches have been utilized as an effective regularizer for the Magnetic Resonance Imaging (MRI) reconstruction. Here, we infuse additional global regularization terms to the patch-based transform learning. We develop an algorithm to solve the resulting novel cost function, which includes both patchwise and global regularization terms. Extensive simulation results indicate that the introduced mixed approach has improved MRI reconstruction performance, when compared to the algorithms which use either of the patchwise transform learning or global regularization terms alone. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Karyotypes, heterochromatin, and physical mapping of 18S-26S rDNA in Cactaceae.

    Science.gov (United States)

    Las Peñas, M L; Urdampilleta, J D; Bernardello, G; Forni-Martins, E R

    2009-01-01

    Karyotype analyses in members of the four Cactaceae subfamilies were performed. Numbers and karyotype formula obtained were: Pereskioideae = Pereskiaaculeata(2n = 22; 10 m + 1 sm), Maihuenioideae = Maihuenia patagonica (2n = 22, 9 m + 2 sm; 2n = 44, 18 m + 4 sm), Opuntioideae = Cumulopuntia recurvata(2n = 44; 20 m + 2 sm), Cactoideae = Acanthocalycium spiniflorum (2n = 22; 10 m + 1 sm),Echinopsis tubiflora (2n = 22; 10 m + 1 sm), Trichocereus candicans (2n = 22, 22 m). Chromosomes were small, the average chromosome length was 2.3 mum. Diploid species and the tetraploid C. recurvata had one terminal satellite, whereas the remaining tetraploid species showed four satellited chromosomes. Karyotypes were symmetrical. No CMA(-)/DAPI(+) bands were detected, but CMA(+)/DAPI(-) bands associated with NOR were always found. Pericentromeric heterochromatin was found in C. recurvata, A. spiniflorum, and the tetraploid cytotype of M. patagonica. The locations of the 18S-26S rDNA sites in all species coincided with CMA(+)/DAPI(-) bands; the same occurred with the sizes and numbers of signals for each species. This technique was applied for the first time in metaphase chromosomes in cacti. NOR-bearing pair no.1 may be homeologous in all species examined. In Cactaceae, the 18S-26S loci seem to be highly conserved. Copyright 2009 S. Karger AG, Basel.

  1. Intravenous Vancomycin Associated With the Development of Nephrotoxicity in Patients With Class III Obesity.

    Science.gov (United States)

    Choi, Yookyung Christy; Saw, Stephen; Soliman, Daniel; Bingham, Angela L; Pontiggia, Laura; Hunter, Krystal; Chuang, Linda; Siemianowski, Laura A; Ereshefsky, Benjamin; Hollands, James M

    2017-11-01

    A consensus statement recommends initial intravenous (IV) vancomycin dosing of 15-20 mg/kg every 8- 24 hours, with an optional 25- to 30-mg/kg loading dose. Although some studies have shown an association between weight and the development of vancomycin-associated nephrotoxicity, results have been inconsistent. To evaluate the correlation between incidence of nephrotoxicity associated with weight-based IV vancomycin dosing strategies in nonobese and obese patients. This retrospective cohort study evaluated hospitalized adult patients admitted who received IV vancomycin. Patients were stratified into nonobese (body mass index [BMI] obesity class I and II (BMI 30-39.9kg/m 2 ), and obesity class III (BMI≥40 kg/m 2 ) groups; patients who were overweight but not obese were excluded. Incidence of nephrotoxicity and serum vancomycin trough concentrations were evaluated. Of a total of 62 documented cases of nephrotoxicity (15.1%), 13 (8.7%), 23 (14.3%), and 26 (26.3%) cases were observed in nonobese, obesity class I and II, and obesity class III groups, respectively ( P=0.002). Longer durations of therapy ( P20 mg/L ( Pobesity were 3-times as likely to develop nephrotoxicity when compared with nonobese patients (odds ratio [OR]=2.99; CI=1.12-7.94) and obesity class I and II patients (OR=3.14; CI=1.27-7.75). Obesity and other factors are associated with a higher risk of vancomycin-associated nephrotoxicity.

  2. Strictly-regular number system and data structures

    DEFF Research Database (Denmark)

    Elmasry, Amr Ahmed Abd Elmoneim; Jensen, Claus; Katajainen, Jyrki

    2010-01-01

    We introduce a new number system that we call the strictly-regular system, which efficiently supports the operations: digit-increment, digit-decrement, cut, concatenate, and add. Compared to other number systems, the strictly-regular system has distinguishable properties. It is superior to the re...

  3. Analysis of regularized Navier-Stokes equations, 2

    Science.gov (United States)

    Ou, Yuh-Roung; Sritharan, S. S.

    1989-01-01

    A practically important regularization of the Navier-Stokes equations was analyzed. As a continuation of the previous work, the structure of the attractors characterizing the solutins was studied. Local as well as global invariant manifolds were found. Regularity properties of these manifolds are analyzed.

  4. Stability of Class II fixed functional appliance therapy—a systematic review and meta-analysis

    Science.gov (United States)

    von Bremen, Julia; Ruf, Sabine

    2016-01-01

    Summary Objectives: To systematically search for scientific evidence concerning the stability of treatment (Tx) results achieved by means of Class II fixed functional appliance therapy and to assess possible differences between appliances. Search Methods: An electronic search of databases and orthodontic journals was carried out (until December 2013), with supplemental hand searching. In addition to the names of all identified appliances, the term fixed functional was used in combination with each of the following search terms: long-term, post-Tx, relapse, retention, stability. Selection Criteria: To be included in the review, the articles had to contain clear data on: Class II Tx with a fixed functional appliance (>5 patients), post-Tx period ≥ 1 year, assessment of ANB angle, Wits appraisal, molar relationship, soft-tissue profile convexity excluding the nose, overjet and/or overbite. Data Collection and Analysis: The literature search revealed 20 scientific investigations which corresponded to only two of the 76 identified appliances (Herbst and Twin Force Bite Corrector). As only one publication was found for the Twin Force Bite Corrector, a meta-analysis could only be performed for Herbst Tx. The data were extracted, pooled and weighted according to the number of patients in each study. Results: The mean values for post-Tx relapse (percentages relative to the Tx changes) were: ANB angle 0.2 degrees (12.4 per cent), Wits appraisal 0.5mm (19.5 per cent), sagittal molar relationship 1.2mm/0.1 cusp widths (21.8 per cent /6.5 per cent); soft-tissue profile convexity excluding nose less than 0.1 degrees (1.0 per cent), overjet 1.8mm (26.2 per cent), overbite Class II:1 1.4mm (44.7 per cent), overbite Class II:2 1.0mm (22.2 per cent). Conclusions: The scientific evidence concerning the stability of Tx results is inexistent for most fixed functional appliances for Class II correction except for Herbst appliance Tx. Even if the evidence level of most included studies

  5. A regularized approach for geodesic-based semisupervised multimanifold learning.

    Science.gov (United States)

    Fan, Mingyu; Zhang, Xiaoqin; Lin, Zhouchen; Zhang, Zhongfei; Bao, Hujun

    2014-05-01

    Geodesic distance, as an essential measurement for data dissimilarity, has been successfully used in manifold learning. However, most geodesic distance-based manifold learning algorithms have two limitations when applied to classification: 1) class information is rarely used in computing the geodesic distances between data points on manifolds and 2) little attention has been paid to building an explicit dimension reduction mapping for extracting the discriminative information hidden in the geodesic distances. In this paper, we regard geodesic distance as a kind of kernel, which maps data from linearly inseparable space to linear separable distance space. In doing this, a new semisupervised manifold learning algorithm, namely regularized geodesic feature learning algorithm, is proposed. The method consists of three techniques: a semisupervised graph construction method, replacement of original data points with feature vectors which are built by geodesic distances, and a new semisupervised dimension reduction method for feature vectors. Experiments on the MNIST, USPS handwritten digit data sets, MIT CBCL face versus nonface data set, and an intelligent traffic data set show the effectiveness of the proposed algorithm.

  6. Regularities, Natural Patterns and Laws of Nature

    Directory of Open Access Journals (Sweden)

    Stathis Psillos

    2014-02-01

    Full Text Available  The goal of this paper is to sketch an empiricist metaphysics of laws of nature. The key idea is that there are regularities without regularity-enforcers. Differently put, there are natural laws without law-makers of a distinct metaphysical kind. This sketch will rely on the concept of a natural pattern and more significantly on the existence of a network of natural patterns in nature. The relation between a regularity and a pattern will be analysed in terms of mereology.  Here is the road map. In section 2, I will briefly discuss the relation between empiricism and metaphysics, aiming to show that an empiricist metaphysics is possible. In section 3, I will offer arguments against stronger metaphysical views of laws. Then, in section 4 I will motivate nomic objectivism. In section 5, I will address the question ‘what is a regularity?’ and will develop a novel answer to it, based on the notion of a natural pattern. In section 6, I will raise the question: ‘what is a law of nature?’, the answer to which will be: a law of nature is a regularity that is characterised by the unity of a natural pattern.

  7. Consistent Partial Least Squares Path Modeling via Regularization.

    Science.gov (United States)

    Jung, Sunho; Park, JaeHong

    2018-01-01

    Partial least squares (PLS) path modeling is a component-based structural equation modeling that has been adopted in social and psychological research due to its data-analytic capability and flexibility. A recent methodological advance is consistent PLS (PLSc), designed to produce consistent estimates of path coefficients in structural models involving common factors. In practice, however, PLSc may frequently encounter multicollinearity in part because it takes a strategy of estimating path coefficients based on consistent correlations among independent latent variables. PLSc has yet no remedy for this multicollinearity problem, which can cause loss of statistical power and accuracy in parameter estimation. Thus, a ridge type of regularization is incorporated into PLSc, creating a new technique called regularized PLSc. A comprehensive simulation study is conducted to evaluate the performance of regularized PLSc as compared to its non-regularized counterpart in terms of power and accuracy. The results show that our regularized PLSc is recommended for use when serious multicollinearity is present.

  8. Consistent Partial Least Squares Path Modeling via Regularization

    Directory of Open Access Journals (Sweden)

    Sunho Jung

    2018-02-01

    Full Text Available Partial least squares (PLS path modeling is a component-based structural equation modeling that has been adopted in social and psychological research due to its data-analytic capability and flexibility. A recent methodological advance is consistent PLS (PLSc, designed to produce consistent estimates of path coefficients in structural models involving common factors. In practice, however, PLSc may frequently encounter multicollinearity in part because it takes a strategy of estimating path coefficients based on consistent correlations among independent latent variables. PLSc has yet no remedy for this multicollinearity problem, which can cause loss of statistical power and accuracy in parameter estimation. Thus, a ridge type of regularization is incorporated into PLSc, creating a new technique called regularized PLSc. A comprehensive simulation study is conducted to evaluate the performance of regularized PLSc as compared to its non-regularized counterpart in terms of power and accuracy. The results show that our regularized PLSc is recommended for use when serious multicollinearity is present.

  9. 40 CFR 26.1118-26.1122 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false [Reserved] 26.1118-26.1122 Section 26.1118-26.1122 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN... Exposure of Non-pregnant, Non-nursing Adults §§ 26.1118-26.1122 [Reserved] ...

  10. 40 CFR 26.1103-26.1106 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false [Reserved] 26.1103-26.1106 Section 26.1103-26.1106 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN... Exposure of Non-pregnant, Non-nursing Adults §§ 26.1103-26.1106 [Reserved] ...

  11. MHC class II B diversity in blue tits : A preliminary study

    NARCIS (Netherlands)

    Rivero-de Aguilar, Juan; Schut, Elske; Merino, Santiago; Martinez, Javier; Komdeur, Jan; Westerdahl, Helena

    In this study, we partly characterize major histocompatibility complex (MHC) class II B in the blue tit (Cyanistes caeruleus). A total of 22 individuals from three different European locations: Spain, The Netherlands, and Sweden were screened for MHC allelic diversity. The MHC genes were

  12. Low-Complexity Regularization Algorithms for Image Deblurring

    KAUST Repository

    Alanazi, Abdulrahman

    2016-11-01

    Image restoration problems deal with images in which information has been degraded by blur or noise. In practice, the blur is usually caused by atmospheric turbulence, motion, camera shake, and several other mechanical or physical processes. In this study, we present two regularization algorithms for the image deblurring problem. We first present a new method based on solving a regularized least-squares (RLS) problem. This method is proposed to find a near-optimal value of the regularization parameter in the RLS problems. Experimental results on the non-blind image deblurring problem are presented. In all experiments, comparisons are made with three benchmark methods. The results demonstrate that the proposed method clearly outperforms the other methods in terms of both the output PSNR and structural similarity, as well as the visual quality of the deblurred images. To reduce the complexity of the proposed algorithm, we propose a technique based on the bootstrap method to estimate the regularization parameter in low and high-resolution images. Numerical results show that the proposed technique can effectively reduce the computational complexity of the proposed algorithms. In addition, for some cases where the point spread function (PSF) is separable, we propose using a Kronecker product so as to reduce the computations. Furthermore, in the case where the image is smooth, it is always desirable to replace the regularization term in the RLS problems by a total variation term. Therefore, we propose a novel method for adaptively selecting the regularization parameter in a so-called square root regularized total variation (SRTV). Experimental results demonstrate that our proposed method outperforms the other benchmark methods when applied to smooth images in terms of PSNR, SSIM and the restored image quality. In this thesis, we focus on the non-blind image deblurring problem, where the blur kernel is assumed to be known. However, we developed algorithms that also work

  13. Improvements in GRACE Gravity Fields Using Regularization

    Science.gov (United States)

    Save, H.; Bettadpur, S.; Tapley, B. D.

    2008-12-01

    The unconstrained global gravity field models derived from GRACE are susceptible to systematic errors that show up as broad "stripes" aligned in a North-South direction on the global maps of mass flux. These errors are believed to be a consequence of both systematic and random errors in the data that are amplified by the nature of the gravity field inverse problem. These errors impede scientific exploitation of the GRACE data products, and limit the realizable spatial resolution of the GRACE global gravity fields in certain regions. We use regularization techniques to reduce these "stripe" errors in the gravity field products. The regularization criteria are designed such that there is no attenuation of the signal and that the solutions fit the observations as well as an unconstrained solution. We have used a computationally inexpensive method, normally referred to as "L-ribbon", to find the regularization parameter. This paper discusses the characteristics and statistics of a 5-year time-series of regularized gravity field solutions. The solutions show markedly reduced stripes, are of uniformly good quality over time, and leave little or no systematic observation residuals, which is a frequent consequence of signal suppression from regularization. Up to degree 14, the signal in regularized solution shows correlation greater than 0.8 with the un-regularized CSR Release-04 solutions. Signals from large-amplitude and small-spatial extent events - such as the Great Sumatra Andaman Earthquake of 2004 - are visible in the global solutions without using special post-facto error reduction techniques employed previously in the literature. Hydrological signals as small as 5 cm water-layer equivalent in the small river basins, like Indus and Nile for example, are clearly evident, in contrast to noisy estimates from RL04. The residual variability over the oceans relative to a seasonal fit is small except at higher latitudes, and is evident without the need for de-striping or

  14. 26 CFR 1.871-1 - Classification and manner of taxing alien individuals.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Classification and manner of taxing alien... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Nonresident Aliens and Foreign Corporations § 1.871-1 Classification and manner of taxing alien individuals. (a) Classes of aliens. For purposes of the income tax...

  15. Comparação entre os resultados oclusais e os tempos de tratamento da má oclusão de Classe II por meio da utilização do aparelho Pendulum e das extrações de dois pré-molares superiores Comparison of the occlusal outcomes and the treatment time of Class II malocclusion with the Pendulum appliance and with extraction of two maxillary premolars

    Directory of Open Access Journals (Sweden)

    Célia Regina Maio Pinzan-Vercelino

    2010-02-01

    Full Text Available OBJETIVO: comparar os resultados oclusais e os tempos de tratamento da má oclusão de Classe II realizado com o aparelho Pendulum e com extrações de dois pré-molares superiores. MÉTODOS: a amostra constituiu-se dos modelos de gesso e das telerradiografias de 48 pacientes com má oclusão de Classe II, divididos em dois grupos de acordo com o protocolo de tratamento. O grupo 1 foi composto por 22 pacientes tratados com o aparelho Pendulum, com idade inicial média de 14,44 anos. O grupo 2 constituiu-se por 26 pacientes tratados com extrações de dois pré-molares superiores, com idade inicial média de 13,66 anos. Os resultados oclusais obtidos pelos dois protocolos de tratamento utilizados foram avaliados em modelos de gesso por meio do índice oclusal PAR, enquanto o tempo de tratamento foi calculado a partir das anotações clínicas presentes nos prontuários. As avaliações foram realizadas por meio do teste t independente. RESULTADOS E CONCLUSÕES: os resultados oclusais obtidos não demonstraram diferenças entre os grupos, porém o grupo 2 apresentou um tempo de tratamento significativamente menor.AIM: The purpose of this study was to compare the occlusal outcomes and the treatment time of Class II malocclusion with the Pendulum appliance and with extraction of two maxillary premolars. METHODS: 48 Class II malocclusion patients were selected and divided into two groups according to the treatment protocol - group 1 consisted of dental study casts and initial cephalograms of 22 patients treated with the Pendulum appliance, with an initial mean age of 14.44 years, and group 2 consisted of dental study casts and initial cephalograms of 26 patients treated with two maxillary premolar extractions and a initial mean age of 13.66 years. The occlusal outcomes were evaluated on dental casts with the PAR occlusal index and the treatment time of each group was calculated by the clinical records. The variables were compared by the t tests

  16. An intelligent fault diagnosis method of rolling bearings based on regularized kernel Marginal Fisher analysis

    International Nuclear Information System (INIS)

    Jiang Li; Shi Tielin; Xuan Jianping

    2012-01-01

    Generally, the vibration signals of fault bearings are non-stationary and highly nonlinear under complicated operating conditions. Thus, it's a big challenge to extract optimal features for improving classification and simultaneously decreasing feature dimension. Kernel Marginal Fisher analysis (KMFA) is a novel supervised manifold learning algorithm for feature extraction and dimensionality reduction. In order to avoid the small sample size problem in KMFA, we propose regularized KMFA (RKMFA). A simple and efficient intelligent fault diagnosis method based on RKMFA is put forward and applied to fault recognition of rolling bearings. So as to directly excavate nonlinear features from the original high-dimensional vibration signals, RKMFA constructs two graphs describing the intra-class compactness and the inter-class separability, by combining traditional manifold learning algorithm with fisher criteria. Therefore, the optimal low-dimensional features are obtained for better classification and finally fed into the simplest K-nearest neighbor (KNN) classifier to recognize different fault categories of bearings. The experimental results demonstrate that the proposed approach improves the fault classification performance and outperforms the other conventional approaches.

  17. Semantic Analysis of Virtual Classes and Nested Classes

    DEFF Research Database (Denmark)

    Madsen, Ole Lehrmann

    1999-01-01

    Virtual classes and nested classes are distinguishing features of BETA. Nested classes originated from Simula, but until recently they have not been part of main stream object- oriented languages. C++ has a restricted form of nested classes and they were included in Java 1.1. Virtual classes...... classes and parameterized classes have been made. Although virtual classes and nested classes have been used in BETA for more than a decade, their implementation has not been published. The purpose of this paper is to contribute to the understanding of virtual classes and nested classes by presenting...

  18. Comorbidity profiles of psoriasis in Taiwan: A latent class analysis.

    Science.gov (United States)

    Wu, Chen-Yi; Hu, Hsiao-Yun; Li, Chung-Pin; Chou, Yiing-Jeng; Chang, Yun-Ting

    2018-01-01

    Psoriasis is associated with many comorbidities. An understanding of these comorbidity patterns can help foster better care of patients with psoriasis. To identify the heterogeneity of psoriasis comorbidities using latent class analysis (LCA). LCA was used to empirically identify psoriasis comorbidity patterns in a nationwide sample of 110,729 incident cases of psoriasis (2002-2012) from the National Health Insurance database in Taiwan. The mean age of incident psoriasis was 46.1 years. Hypertension (28.8%), dyslipidemia (18.9%), and chronic liver disease/cirrhosis/hepatitis (18.1%) were the top three comorbidities in patients with psoriasis. LCA identified four distinct comorbidity classes among these patients, including 9.9% of patients in the "multi-comorbidity" class, 17.9% in the "metabolic syndrome" class, 11.3% in the "hypertension and chronic obstructive pulmonary disease (COPD)" class, and 60.9% in the "relatively healthy" class. Psoriatic arthritis was evenly distributed among each class. Relative to membership in the "relative healthy" class, an increase of one year of age had a higher probability of membership in the "multi-comorbidity" (odds ratio [OR], 1.25), "metabolic syndrome" (OR, 1.11), or "hypertension and COPD" (OR, 1.34) classes. Relative to membership in the "relative healthy" class, compared to women, men had a higher probability of membership in the "multi-comorbidity" (OR, 1.39), "metabolic syndrome" (OR, 1.77), or "hypertension and COPD" (OR, 1.22) classes. We observed four distinct classes of psoriasis comorbidities, including the "multi-comorbidity", "metabolic syndrome", "hypertension and COPD", and "relatively healthy" classes, as well as the clustering of liver diseases with metabolic syndrome and clustering of COPD with hypertension.

  19. 22nd Italian Workshop on Neural Nets

    CERN Document Server

    Bassis, Simone; Esposito, Anna; Morabito, Francesco

    2013-01-01

    This volume collects a selection of contributions which has been presented at the 22nd Italian Workshop on Neural Networks, the yearly meeting of the Italian Society for Neural Networks (SIREN). The conference was held in Italy, Vietri sul Mare (Salerno), during May 17-19, 2012. The annual meeting of SIREN is sponsored by International Neural Network Society (INNS), European Neural Network Society (ENNS) and IEEE Computational Intelligence Society (CIS). The book – as well as the workshop-  is organized in three main components, two special sessions and a group of regular sessions featuring different aspects and point of views of artificial neural networks and natural intelligence, also including applications of present compelling interest.

  20. Deterministic automata for extended regular expressions

    Directory of Open Access Journals (Sweden)

    Syzdykov Mirzakhmet

    2017-12-01

    Full Text Available In this work we present the algorithms to produce deterministic finite automaton (DFA for extended operators in regular expressions like intersection, subtraction and complement. The method like “overriding” of the source NFA(NFA not defined with subset construction rules is used. The past work described only the algorithm for AND-operator (or intersection of regular languages; in this paper the construction for the MINUS-operator (and complement is shown.

  1. Regularities of intermediate adsorption complex relaxation

    International Nuclear Information System (INIS)

    Manukova, L.A.

    1982-01-01

    The experimental data, characterizing the regularities of intermediate adsorption complex relaxation in the polycrystalline Mo-N 2 system at 77 K are given. The method of molecular beam has been used in the investigation. The analytical expressions of change regularity in the relaxation process of full and specific rates - of transition from intermediate state into ''non-reversible'', of desorption into the gas phase and accumUlation of the particles in the intermediate state are obtained

  2. A class of conservative Hamiltonians with exactly integrable discrete two-dimensional parametric maps

    International Nuclear Information System (INIS)

    Dikande, Alain M; Njumbe, E Epie

    2010-01-01

    A class of discrete conservative Hamiltonians with completely integrable two-dimensional (2D) mappings is constructed whose generic models are three families of non-integrable discrete Hamiltonians with on-site potentials whose double-well shapes vary. Unlike the discrete 2D mappings associated with the generic models, which all display pitchfork bifurcations towards randomly pinned states with chaotic features, for the derived models the pitchfork bifurcation leads to fixed points always surrounded by periodic trajectories. A nonlinear stability analysis reveals a finite crossover on the bifurcation line at which the pitchfork transition takes the maps from regular real periodic trajectories towards a regime dominated by a cluster of periodic point trajectories representing the allowed real solutions. The rich variety of structures displayed by the new class of discrete maps, combined with their complete integrability, offer rich perspectives for theoretical modelling of a wide class of systems undergoing structural instabilities without noticeable chaotic precursors.

  3. Sparse structure regularized ranking

    KAUST Repository

    Wang, Jim Jing-Yan; Sun, Yijun; Gao, Xin

    2014-01-01

    Learning ranking scores is critical for the multimedia database retrieval problem. In this paper, we propose a novel ranking score learning algorithm by exploring the sparse structure and using it to regularize ranking scores. To explore the sparse

  4. Sparse structure regularized ranking

    KAUST Repository

    Wang, Jim Jing-Yan

    2014-04-17

    Learning ranking scores is critical for the multimedia database retrieval problem. In this paper, we propose a novel ranking score learning algorithm by exploring the sparse structure and using it to regularize ranking scores. To explore the sparse structure, we assume that each multimedia object could be represented as a sparse linear combination of all other objects, and combination coefficients are regarded as a similarity measure between objects and used to regularize their ranking scores. Moreover, we propose to learn the sparse combination coefficients and the ranking scores simultaneously. A unified objective function is constructed with regard to both the combination coefficients and the ranking scores, and is optimized by an iterative algorithm. Experiments on two multimedia database retrieval data sets demonstrate the significant improvements of the propose algorithm over state-of-the-art ranking score learning algorithms.

  5. 20 CFR 226.35 - Deductions from regular annuity rate.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Deductions from regular annuity rate. 226.35... COMPUTING EMPLOYEE, SPOUSE, AND DIVORCED SPOUSE ANNUITIES Computing a Spouse or Divorced Spouse Annuity § 226.35 Deductions from regular annuity rate. The regular annuity rate of the spouse and divorced...

  6. Extending positive CLASS results across multiple instructors and multiple classes of Modeling Instruction

    Science.gov (United States)

    Brewe, Eric; Traxler, Adrienne; de la Garza, Jorge; Kramer, Laird H.

    2013-12-01

    We report on a multiyear study of student attitudes measured with the Colorado Learning Attitudes about Science Survey in calculus-based introductory physics taught with the Modeling Instruction curriculum. We find that five of six instructors and eight of nine sections using Modeling Instruction showed significantly improved attitudes from pre- to postcourse. Cohen’s d effect sizes range from 0.08 to 0.95 for individual instructors. The average effect was d=0.45, with a 95% confidence interval of (0.26-0.64). These results build on previously published results showing positive shifts in attitudes from Modeling Instruction classes. We interpret these data in light of other published positive attitudinal shifts and explore mechanistic explanations for similarities and differences with other published positive shifts.

  7. Regularization theory for ill-posed problems selected topics

    CERN Document Server

    Lu, Shuai

    2013-01-01

    Thismonograph is a valuable contribution to thehighly topical and extremly productive field ofregularisationmethods for inverse and ill-posed problems. The author is an internationally outstanding and acceptedmathematicianin this field. In his book he offers a well-balanced mixtureof basic and innovative aspects.He demonstrates new,differentiatedviewpoints, and important examples for applications. The bookdemontrates thecurrent developments inthe field of regularization theory,such as multiparameter regularization and regularization in learning theory. The book is written for graduate and PhDs

  8. 49 CFR 1242.22 - Shop buildings-locomotives (account XX-19-24).

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Shop buildings-locomotives (account XX-19-24... Structures § 1242.22 Shop buildings—locomotives (account XX-19-24). Separate common expenses according to distribution of common expenses in the following accounts: Machinery Repair (XX-26-40) Locomotive—Repair and...

  9. 20 CFR 226.34 - Divorced spouse regular annuity rate.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Divorced spouse regular annuity rate. 226.34... COMPUTING EMPLOYEE, SPOUSE, AND DIVORCED SPOUSE ANNUITIES Computing a Spouse or Divorced Spouse Annuity § 226.34 Divorced spouse regular annuity rate. The regular annuity rate of a divorced spouse is equal to...

  10. Chimeric mitochondrial peptides from contiguous regular and swinger RNA.

    Science.gov (United States)

    Seligmann, Hervé

    2016-01-01

    Previous mass spectrometry analyses described human mitochondrial peptides entirely translated from swinger RNAs, RNAs where polymerization systematically exchanged nucleotides. Exchanges follow one among 23 bijective transformation rules, nine symmetric exchanges (X ↔ Y, e.g. A ↔ C) and fourteen asymmetric exchanges (X → Y → Z → X, e.g. A → C → G → A), multiplying by 24 DNA's protein coding potential. Abrupt switches from regular to swinger polymerization produce chimeric RNAs. Here, human mitochondrial proteomic analyses assuming abrupt switches between regular and swinger transcriptions, detect chimeric peptides, encoded by part regular, part swinger RNA. Contiguous regular- and swinger-encoded residues within single peptides are stronger evidence for translation of swinger RNA than previously detected, entirely swinger-encoded peptides: regular parts are positive controls matched with contiguous swinger parts, increasing confidence in results. Chimeric peptides are 200 × rarer than swinger peptides (3/100,000 versus 6/1000). Among 186 peptides with > 8 residues for each regular and swinger parts, regular parts of eleven chimeric peptides correspond to six among the thirteen recognized, mitochondrial protein-coding genes. Chimeric peptides matching partly regular proteins are rarer and less expressed than chimeric peptides matching non-coding sequences, suggesting targeted degradation of misfolded proteins. Present results strengthen hypotheses that the short mitogenome encodes far more proteins than hitherto assumed. Entirely swinger-encoded proteins could exist.

  11. Fast and compact regular expression matching

    DEFF Research Database (Denmark)

    Bille, Philip; Farach-Colton, Martin

    2008-01-01

    We study 4 problems in string matching, namely, regular expression matching, approximate regular expression matching, string edit distance, and subsequence indexing, on a standard word RAM model of computation that allows logarithmic-sized words to be manipulated in constant time. We show how...... to improve the space and/or remove a dependency on the alphabet size for each problem using either an improved tabulation technique of an existing algorithm or by combining known algorithms in a new way....

  12. SINET: Ethiopian Journal of Science - Vol 26, No 1 (2003)

    African Journals Online (AJOL)

    Electronic properties of poly[3-(2”,5”-diheptyloxyphenyl)-2,2'-bithiophene]/Al junctions · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Taha A Abdalla, Wendimagegn Mammo, Bantikassegn Workalemahu, 11-16. http://dx.doi.org/10.4314/sinet.v26i1.18194 ...

  13. Dimensional regularization and analytical continuation at finite temperature

    International Nuclear Information System (INIS)

    Chen Xiangjun; Liu Lianshou

    1998-01-01

    The relationship between dimensional regularization and analytical continuation of infrared divergent integrals at finite temperature is discussed and a method of regularization of infrared divergent integrals and infrared divergent sums is given

  14. Six équipes de chercheurs de classe mondiale étudieront comment ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Six équipes de chercheurs de classe mondiale étudieront comment surmonter la résistance au traitement des cancers les plus mortels. 26 octobre 2017. Avec nos partenaires, les Instituts de recherche en santé du Canada, l'Azrieli Foundation et l'Israel Science Foundation, nous sommes heureux de dévoiler l'identité des ...

  15. Regular and conformal regular cores for static and rotating solutions

    Energy Technology Data Exchange (ETDEWEB)

    Azreg-Aïnou, Mustapha

    2014-03-07

    Using a new metric for generating rotating solutions, we derive in a general fashion the solution of an imperfect fluid and that of its conformal homolog. We discuss the conditions that the stress–energy tensors and invariant scalars be regular. On classical physical grounds, it is stressed that conformal fluids used as cores for static or rotating solutions are exempt from any malicious behavior in that they are finite and defined everywhere.

  16. Regular and conformal regular cores for static and rotating solutions

    International Nuclear Information System (INIS)

    Azreg-Aïnou, Mustapha

    2014-01-01

    Using a new metric for generating rotating solutions, we derive in a general fashion the solution of an imperfect fluid and that of its conformal homolog. We discuss the conditions that the stress–energy tensors and invariant scalars be regular. On classical physical grounds, it is stressed that conformal fluids used as cores for static or rotating solutions are exempt from any malicious behavior in that they are finite and defined everywhere.

  17. Factors associated with a continuous regular analgesic use - a population-based study of more than 45,000 Danish women and men 18-45 years of age.

    Science.gov (United States)

    Hargreave, Marie; Andersen, Tina Veje; Nielsen, Ann; Munk, Christian; Liaw, Kai-Li; Kjaer, Susanne K

    2010-01-01

    Widespread use of and serious adverse effects associated with use of analgesics accentuates the need to consider factors related to analgesic use. The objective of this study was to describe continuous regular analgesics use and examine factors associated with a continuous regular analgesic use. The study was based on data from two surveys and included a random sample of women and men aged 18-45 years from the general Danish population. Information on analgesics use, self-rated health, demographic and lifestyle factors was collected using a self-administered questionnaire. A total of 28,000 women and 33 000 men were invited to participate and 22,199 women (response-rate 81.4%) and 23,080 men (response-rate 71.0%), respectively, were included in the study. Data were analyzed using multivariate logistic regression. We found that 27% of the women and 18% of the men reported a regular monthly use of at least seven analgesic tablets during the last year (continuous regular analgesics use). Besides poor self-rated health we found in both sexes that increasing age, poor self-rated fitness, and smoking were related to a continuous regular analgesics use. Nulliparity, low level of education, overweight/obesity, binge drinking, and abstinence were associated with a continuous regular analgesics use for women, while underweight and marital/cohabiting status were associated with a continuous regular analgesics use only for men. Regular monthly analgesic use during the last year was generally prevalent. Besides self-rated health, several socio-demographic and lifestyle factors were associated with a continuous regular analgesic use, although with some gender differences.

  18. India | Page 26 | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    22 · 23 · 24 · 25; 26; 27 · 28 · 29 · 30 … next › · last » · What we do · Funding · Resources · About IDRC. Knowledge. Innovation. Solutions. Careers · Contact Us · Site map · Copyright · Open access policy · Privacy policy · Research ethics · Transparency · Website usage. Follow us; Facebook · Twitter · Youtube · Linked In ...

  19. Kenya | Page 26 | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    22 · 23 · 24 · 25; 26; 27 · 28 · 29 · 30 … next › · last » · What we do · Funding · Resources · About IDRC. Knowledge. Innovation. Solutions. Careers · Contact Us · Site map · Copyright · Open access policy · Privacy policy · Research ethics · Transparency · Website usage. Follow us; Facebook · Twitter · Youtube · Linked In ...

  20. Far East Asia | Page 26 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    22 · 23 · 24 · 25; 26; 27 · 28 · 29 · 30 … next › · last » · What we do · Funding · Resources · About IDRC. Knowledge. Innovation. Solutions. Careers · Contact Us · Site map · Copyright · Open access policy · Privacy policy · Research ethics · Transparency · Website usage. Follow us; Facebook · Twitter · Youtube · Linked In ...

  1. 22 CFR 171.22 - Appeals.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Appeals. 171.22 Section 171.22 Foreign Relations DEPARTMENT OF STATE ACCESS TO INFORMATION AVAILABILITY OF INFORMATION AND RECORDS TO THE PUBLIC Executive Order 12958 Provisions § 171.22 Appeals. Any denial of a mandatory declassification review request...

  2. The Position of Hyoici Bone in Skeletal Class I, II and III Patients

    Directory of Open Access Journals (Sweden)

    Ravanmehr H

    2000-06-01

    Full Text Available In this investigation, the position of hyoid bone was compared in three skeletal groups of class I, II and III. The study was based on evaluating 77 lateral cephalometric radiographs, 40 girls and 37 boys, which were divided into 3 groups. Group 1, 2, and 3 consist of 26, 25, and 26 radiographs. 19 cephalometric landmarks and 10 planes were used in order to tracing the radiographs. In all patients, 9 skeletal and 4 cervical vertebrae parameters were measured to determine the hyoid bone. These parameters were compared between three skeletal groups regardless of sex and then, in another statistical analysis, parameters were compared based on patients sex. Statistical analysis showed that in class III patients, the hyoid bone was positioned more anteriorly than two other groups. Also in this group, the hyoid bone had less inclination and it was more horizontal in relation to mandibular plane. In skeletal class II patients this bone was positioned more superiorly than two other groups. Due to these findings it can be concluded that perimandibular muscles and bones could affect the growth of mandible. In addition, comparison of the parameters between two sexes revealed that the hyoid bone was positioned more anteriorly and inferiorly in boys. Also it was shown that in the girls, the position of hyoid bone was closer to the position of this bone in skeletal class I patients.

  3. Low-rank matrix approximation with manifold regularization.

    Science.gov (United States)

    Zhang, Zhenyue; Zhao, Keke

    2013-07-01

    This paper proposes a new model of low-rank matrix factorization that incorporates manifold regularization to the matrix factorization. Superior to the graph-regularized nonnegative matrix factorization, this new regularization model has globally optimal and closed-form solutions. A direct algorithm (for data with small number of points) and an alternate iterative algorithm with inexact inner iteration (for large scale data) are proposed to solve the new model. A convergence analysis establishes the global convergence of the iterative algorithm. The efficiency and precision of the algorithm are demonstrated numerically through applications to six real-world datasets on clustering and classification. Performance comparison with existing algorithms shows the effectiveness of the proposed method for low-rank factorization in general.

  4. Regularity criteria for incompressible magnetohydrodynamics equations in three dimensions

    International Nuclear Information System (INIS)

    Lin, Hongxia; Du, Lili

    2013-01-01

    In this paper, we give some new global regularity criteria for three-dimensional incompressible magnetohydrodynamics (MHD) equations. More precisely, we provide some sufficient conditions in terms of the derivatives of the velocity or pressure, for the global regularity of strong solutions to 3D incompressible MHD equations in the whole space, as well as for periodic boundary conditions. Moreover, the regularity criterion involving three of the nine components of the velocity gradient tensor is also obtained. The main results generalize the recent work by Cao and Wu (2010 Two regularity criteria for the 3D MHD equations J. Diff. Eqns 248 2263–74) and the analysis in part is based on the works by Cao C and Titi E (2008 Regularity criteria for the three-dimensional Navier–Stokes equations Indiana Univ. Math. J. 57 2643–61; 2011 Gobal regularity criterion for the 3D Navier–Stokes equations involving one entry of the velocity gradient tensor Arch. Rational Mech. Anal. 202 919–32) for 3D incompressible Navier–Stokes equations. (paper)

  5. On structure-exploiting trust-region regularized nonlinear least squares algorithms for neural-network learning.

    Science.gov (United States)

    Mizutani, Eiji; Demmel, James W

    2003-01-01

    This paper briefly introduces our numerical linear algebra approaches for solving structured nonlinear least squares problems arising from 'multiple-output' neural-network (NN) models. Our algorithms feature trust-region regularization, and exploit sparsity of either the 'block-angular' residual Jacobian matrix or the 'block-arrow' Gauss-Newton Hessian (or Fisher information matrix in statistical sense) depending on problem scale so as to render a large class of NN-learning algorithms 'efficient' in both memory and operation costs. Using a relatively large real-world nonlinear regression application, we shall explain algorithmic strengths and weaknesses, analyzing simulation results obtained by both direct and iterative trust-region algorithms with two distinct NN models: 'multilayer perceptrons' (MLP) and 'complementary mixtures of MLP-experts' (or neuro-fuzzy modular networks).

  6. Regular-fat dairy and human health

    DEFF Research Database (Denmark)

    Astrup, Arne; Bradley, Beth H Rice; Brenna, J Thomas

    2016-01-01

    In recent history, some dietary recommendations have treated dairy fat as an unnecessary source of calories and saturated fat in the human diet. These assumptions, however, have recently been brought into question by current research on regular fat dairy products and human health. In an effort to......, cheese and yogurt, can be important components of an overall healthy dietary pattern. Systematic examination of the effects of dietary patterns that include regular-fat milk, cheese and yogurt on human health is warranted....

  7. 76 FR 22009 - Amendment of Class E Airspace; Terre Haute, IN

    Science.gov (United States)

    2011-04-20

    ...-1034; Airspace Docket No. 10-AGL-22] Amendment of Class E Airspace; Terre Haute, IN AGENCY: Federal... Terre Haute, IN, to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures at Union Hospital Heliport, Terre Haute, IN. The FAA is taking this action to enhance the safety and...

  8. Bounded Perturbation Regularization for Linear Least Squares Estimation

    KAUST Repository

    Ballal, Tarig; Suliman, Mohamed Abdalla Elhag; Al-Naffouri, Tareq Y.

    2017-01-01

    This paper addresses the problem of selecting the regularization parameter for linear least-squares estimation. We propose a new technique called bounded perturbation regularization (BPR). In the proposed BPR method, a perturbation with a bounded

  9. Social class, social mobility and alcohol-related disorders in Swedish men and women: A study of four generations.

    Science.gov (United States)

    Sidorchuk, Anna; Goodman, Anna; Koupil, Ilona

    2018-01-01

    To investigate whether and how social class and social mobility in grandparents and parents predict alcohol-related disorders (ARDs) in males and females aged 12+ years, and whether intergenerational social prediction of ARDs varies across time periods. The study sample included four successive generations (G) of Swedish families from the Uppsala Birth Cohort Multigenerational Study: G0 born 1851-1912; G1 born 1915-1929; G2 born 1940-1964 and G3 born 1965-1989. Two study populations were created, each consisting of grandparents, parents and offspring: population I 'G0-G1-G2' (offspring n = 18 430) and population II 'G1-G2-G3' (offspring n = 26 469). Registers and archives provided data on ancestors' socio-demographic factors and ARD history, together with offspring ARD development between 1964-2008. Cox regression models examined the hazard of offspring ARD development according to grandparental social class and grandparental-to-parental social trajectories, controlling for offspring birth year, grandmother's and mother's marital status and parental ARDs. Disadvantaged grandparental social class predicted increased ARD risk in offspring in population I, although the effect attenuated and became non-significant in males after adjusting for parental characteristics (adjusted hazard ratio (HR) = 1.80 (95%CI; 1.07, 3.03) in females, HR = 1.32 (95%CI; 0.93, 1.89) in males). In population II, no increase in ARD risk by grandparental social was evident. In both populations, males were at the highest ARD risk if both parents and grandparents belonged to disadvantaged social class (population I: HR = 1.82 (95%CI; 1.22-2.72); population II: HR = 1.68 (95%CI; 1.02-2.76)). Intergenerational social patterning of ARDs appears to be time-contextual and gender-specific. The role of grandparental social class in developing ARDs in grandchildren seems to decline over time, while persistent grandparental-to-parental social disadvantage remains associated with higher ARD risk in males

  10. Support Vector Data Descriptions and k-Means Clustering: One Class?

    Science.gov (United States)

    Gornitz, Nico; Lima, Luiz Alberto; Muller, Klaus-Robert; Kloft, Marius; Nakajima, Shinichi

    2017-09-27

    We present ClusterSVDD, a methodology that unifies support vector data descriptions (SVDDs) and k-means clustering into a single formulation. This allows both methods to benefit from one another, i.e., by adding flexibility using multiple spheres for SVDDs and increasing anomaly resistance and flexibility through kernels to k-means. In particular, our approach leads to a new interpretation of k-means as a regularized mode seeking algorithm. The unifying formulation further allows for deriving new algorithms by transferring knowledge from one-class learning settings to clustering settings and vice versa. As a showcase, we derive a clustering method for structured data based on a one-class learning scenario. Additionally, our formulation can be solved via a particularly simple optimization scheme. We evaluate our approach empirically to highlight some of the proposed benefits on artificially generated data, as well as on real-world problems, and provide a Python software package comprising various implementations of primal and dual SVDD as well as our proposed ClusterSVDD.

  11. Recognition Memory for Novel Stimuli: The Structural Regularity Hypothesis

    Science.gov (United States)

    Cleary, Anne M.; Morris, Alison L.; Langley, Moses M.

    2007-01-01

    Early studies of human memory suggest that adherence to a known structural regularity (e.g., orthographic regularity) benefits memory for an otherwise novel stimulus (e.g., G. A. Miller, 1958). However, a more recent study suggests that structural regularity can lead to an increase in false-positive responses on recognition memory tests (B. W. A.…

  12. Pupil Selection Segments Urban Comprehensive Schooling in Finland: Composition of School Classes in Pupils' School Performance, Gender, and Ethnicity

    Science.gov (United States)

    Berisha, Anna-Kaisa; Seppänen, Piia

    2017-01-01

    The Finnish comprehensive school system is regularly referred to as a uniform and "no-tracking". In this article, we show with novel urban case data in Finland that school performance differed significantly between schools, most strikingly between school classes, and was connected to the school's selectiveness in pupil admission. A…

  13. DOE ZERH Case Study: Greenhill Contracting, Green Acres #20, #26, #28, New Paltz, NY

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2015-09-01

    Case study of three DOE 2015 Housing Innovation Award winning custom homes in the cold climate that got a HERS of 26, 28, and 26 without PV or -3, -1, and -3.5 with PV; with R-22 ICFs, 10” ocsf plus 2.7” c ccsf in attic; ICF basements with 4.3” ccsf under slab; tri;e-pane windows; ERVs, ground source heat pumps (COP 5.7).

  14. Regularization Techniques for Linear Least-Squares Problems

    KAUST Repository

    Suliman, Mohamed

    2016-04-01

    Linear estimation is a fundamental branch of signal processing that deals with estimating the values of parameters from a corrupted measured data. Throughout the years, several optimization criteria have been used to achieve this task. The most astonishing attempt among theses is the linear least-squares. Although this criterion enjoyed a wide popularity in many areas due to its attractive properties, it appeared to suffer from some shortcomings. Alternative optimization criteria, as a result, have been proposed. These new criteria allowed, in one way or another, the incorporation of further prior information to the desired problem. Among theses alternative criteria is the regularized least-squares (RLS). In this thesis, we propose two new algorithms to find the regularization parameter for linear least-squares problems. In the constrained perturbation regularization algorithm (COPRA) for random matrices and COPRA for linear discrete ill-posed problems, an artificial perturbation matrix with a bounded norm is forced into the model matrix. This perturbation is introduced to enhance the singular value structure of the matrix. As a result, the new modified model is expected to provide a better stabilize substantial solution when used to estimate the original signal through minimizing the worst-case residual error function. Unlike many other regularization algorithms that go in search of minimizing the estimated data error, the two new proposed algorithms are developed mainly to select the artifcial perturbation bound and the regularization parameter in a way that approximately minimizes the mean-squared error (MSE) between the original signal and its estimate under various conditions. The first proposed COPRA method is developed mainly to estimate the regularization parameter when the measurement matrix is complex Gaussian, with centered unit variance (standard), and independent and identically distributed (i.i.d.) entries. Furthermore, the second proposed COPRA

  15. Surgical-orthodontic correction of a Class III dentofacial deformity.

    Science.gov (United States)

    Devanna, Raghu; Kakkirala, Neelima

    2010-04-01

    This case report describes the surgical-orthodontic treatment of a 26-year-old post-pubertal male patient with a Class III dentofacial deformity. In the pre-surgical orthodontic phase of treatment, a reverse overjet of 5.5 mm was created and arch compatibility was obtained. A mandibualr set back with BSSO was performed during surgery to restore ideal overjet, overbite, occlusion and optimal esthetics. After 1 year of treatment, the results remained stable.

  16. Regularized Regression and Density Estimation based on Optimal Transport

    KAUST Repository

    Burger, M.

    2012-03-11

    The aim of this paper is to investigate a novel nonparametric approach for estimating and smoothing density functions as well as probability densities from discrete samples based on a variational regularization method with the Wasserstein metric as a data fidelity. The approach allows a unified treatment of discrete and continuous probability measures and is hence attractive for various tasks. In particular, the variational model for special regularization functionals yields a natural method for estimating densities and for preserving edges in the case of total variation regularization. In order to compute solutions of the variational problems, a regularized optimal transport problem needs to be solved, for which we discuss several formulations and provide a detailed analysis. Moreover, we compute special self-similar solutions for standard regularization functionals and we discuss several computational approaches and results. © 2012 The Author(s).

  17. Energy functions for regularization algorithms

    Science.gov (United States)

    Delingette, H.; Hebert, M.; Ikeuchi, K.

    1991-01-01

    Regularization techniques are widely used for inverse problem solving in computer vision such as surface reconstruction, edge detection, or optical flow estimation. Energy functions used for regularization algorithms measure how smooth a curve or surface is, and to render acceptable solutions these energies must verify certain properties such as invariance with Euclidean transformations or invariance with parameterization. The notion of smoothness energy is extended here to the notion of a differential stabilizer, and it is shown that to void the systematic underestimation of undercurvature for planar curve fitting, it is necessary that circles be the curves of maximum smoothness. A set of stabilizers is proposed that meet this condition as well as invariance with rotation and parameterization.

  18. Three regularities of recognition memory: the role of bias.

    Science.gov (United States)

    Hilford, Andrew; Maloney, Laurence T; Glanzer, Murray; Kim, Kisok

    2015-12-01

    A basic assumption of Signal Detection Theory is that decisions are made on the basis of likelihood ratios. In a preceding paper, Glanzer, Hilford, and Maloney (Psychonomic Bulletin & Review, 16, 431-455, 2009) showed that the likelihood ratio assumption implies that three regularities will occur in recognition memory: (1) the Mirror Effect, (2) the Variance Effect, (3) the normalized Receiver Operating Characteristic (z-ROC) Length Effect. The paper offered formal proofs and computational demonstrations that decisions based on likelihood ratios produce the three regularities. A survey of data based on group ROCs from 36 studies validated the likelihood ratio assumption by showing that its three implied regularities are ubiquitous. The study noted, however, that bias, another basic factor in Signal Detection Theory, can obscure the Mirror Effect. In this paper we examine how bias affects the regularities at the theoretical level. The theoretical analysis shows: (1) how bias obscures the Mirror Effect, not the other two regularities, and (2) four ways to counter that obscuring. We then report the results of five experiments that support the theoretical analysis. The analyses and the experimental results also demonstrate: (1) that the three regularities govern individual, as well as group, performance, (2) alternative explanations of the regularities are ruled out, and (3) that Signal Detection Theory, correctly applied, gives a simple and unified explanation of recognition memory data.

  19. Method of transferring regular shaped vessel into cell

    International Nuclear Information System (INIS)

    Murai, Tsunehiko.

    1997-01-01

    The present invention concerns a method of transferring regular shaped vessels from a non-contaminated area to a contaminated cell. A passage hole for allowing the regular shaped vessels to pass in the longitudinal direction is formed to a partitioning wall at the bottom of the contaminated cell. A plurality of regular shaped vessel are stacked in multiple stages in a vertical direction from the non-contaminated area present below the passage hole, allowed to pass while being urged and transferred successively into the contaminated cell. As a result, since they are transferred while substantially closing the passage hole by the regular shaped vessels, radiation rays or contaminated materials are prevented from discharging from the contaminated cell to the non-contaminated area. Since there is no requirement to open/close an isolation door frequently, the workability upon transfer can be improved remarkably. In addition, the sealing member for sealing the gap between the regular shaped vessel passing through the passage hole and the partitioning wall of the bottom is disposed to the passage hole, the contaminated materials in the contaminated cells can be prevented from discharging from the gap to the non-contaminated area. (N.H.)

  20. Identifying factors associated with regular physical activity in leisure time among Canadian adolescents.

    Science.gov (United States)

    Godin, Gaston; Anderson, Donna; Lambert, Léo-Daniel; Desharnais, Raymond

    2005-01-01

    The purpose of this study was to identify the factors explaining regular physical activity among Canadian adolescents. A cohort study conducted over a period of 2 years. A French-language high school located near Québec City. A cohort of 740 students (352 girls; 388 boys) aged 13.3 +/- 1.0 years at baseline. Psychosocial, life context, profile, and sociodemographic variables were assessed at baseline and 1 and 2 years after baseline. Exercising almost every day during leisure time at each measurement time was the dependent variable. The Generalized Estimating Equations (GEE) analysis indicated that exercising almost every day was significantly associated with a high intention to exercise (odds ratio [OR]: 8.33, confidence interval [CI] 95%: 5.26, 13.18), being satisfied with the activity practiced (OR: 2.07, CI 95%: 1.27, 3.38), perceived descriptive norm (OR: 1.82, CI 95%: 1.41, 2.35), being a boy (OR: 1.83, CI 95%: 1.37, 2.46), practicing "competitive" activities (OR: 1.80, CI 95%: 1.37, 2.36), eating a healthy breakfast (OR: 1.68, CI 95%: 1.09, 2.60), and normative beliefs (OR: 1.48, CI 95%: 1.14, 1.90). Specific GEE analysis for gender indicated slight but significant differences. This study provides evidence for the need to design interventions that are gender specific and that focus on increasing intention to exercise regularly.

  1. Automatic Constraint Detection for 2D Layout Regularization.

    Science.gov (United States)

    Jiang, Haiyong; Nan, Liangliang; Yan, Dong-Ming; Dong, Weiming; Zhang, Xiaopeng; Wonka, Peter

    2016-08-01

    In this paper, we address the problem of constraint detection for layout regularization. The layout we consider is a set of two-dimensional elements where each element is represented by its bounding box. Layout regularization is important in digitizing plans or images, such as floor plans and facade images, and in the improvement of user-created contents, such as architectural drawings and slide layouts. To regularize a layout, we aim to improve the input by detecting and subsequently enforcing alignment, size, and distance constraints between layout elements. Similar to previous work, we formulate layout regularization as a quadratic programming problem. In addition, we propose a novel optimization algorithm that automatically detects constraints. We evaluate the proposed framework using a variety of input layouts from different applications. Our results demonstrate that our method has superior performance to the state of the art.

  2. Automatic Constraint Detection for 2D Layout Regularization

    KAUST Repository

    Jiang, Haiyong

    2015-09-18

    In this paper, we address the problem of constraint detection for layout regularization. As layout we consider a set of two-dimensional elements where each element is represented by its bounding box. Layout regularization is important for digitizing plans or images, such as floor plans and facade images, and for the improvement of user created contents, such as architectural drawings and slide layouts. To regularize a layout, we aim to improve the input by detecting and subsequently enforcing alignment, size, and distance constraints between layout elements. Similar to previous work, we formulate the layout regularization as a quadratic programming problem. In addition, we propose a novel optimization algorithm to automatically detect constraints. In our results, we evaluate the proposed framework on a variety of input layouts from different applications, which demonstrates our method has superior performance to the state of the art.

  3. Lavrentiev regularization method for nonlinear ill-posed problems

    International Nuclear Information System (INIS)

    Kinh, Nguyen Van

    2002-10-01

    In this paper we shall be concerned with Lavientiev regularization method to reconstruct solutions x 0 of non ill-posed problems F(x)=y o , where instead of y 0 noisy data y δ is an element of X with absolut(y δ -y 0 ) ≤ δ are given and F:X→X is an accretive nonlinear operator from a real reflexive Banach space X into itself. In this regularization method solutions x α δ are obtained by solving the singularly perturbed nonlinear operator equation F(x)+α(x-x*)=y δ with some initial guess x*. Assuming certain conditions concerning the operator F and the smoothness of the element x*-x 0 we derive stability estimates which show that the accuracy of the regularized solutions is order optimal provided that the regularization parameter α has been chosen properly. (author)

  4. Online Manifold Regularization by Dual Ascending Procedure

    Directory of Open Access Journals (Sweden)

    Boliang Sun

    2013-01-01

    Full Text Available We propose a novel online manifold regularization framework based on the notion of duality in constrained optimization. The Fenchel conjugate of hinge functions is a key to transfer manifold regularization from offline to online in this paper. Our algorithms are derived by gradient ascent in the dual function. For practical purpose, we propose two buffering strategies and two sparse approximations to reduce the computational complexity. Detailed experiments verify the utility of our approaches. An important conclusion is that our online MR algorithms can handle the settings where the target hypothesis is not fixed but drifts with the sequence of examples. We also recap and draw connections to earlier works. This paper paves a way to the design and analysis of online manifold regularization algorithms.

  5. 19 CFR 133.26 - Demand for redelivery of released merchandise.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Demand for redelivery of released merchandise. 133... Recorded Trademarks or Recorded Trade Names § 133.26 Demand for redelivery of released merchandise. If it... restrictions of § 133.22 or § 133.23 of this subpart, the port director shall promptly make demand for the...

  6. Class prediction for high-dimensional class-imbalanced data

    Directory of Open Access Journals (Sweden)

    Lusa Lara

    2010-10-01

    Full Text Available Abstract Background The goal of class prediction studies is to develop rules to accurately predict the class membership of new samples. The rules are derived using the values of the variables available for each subject: the main characteristic of high-dimensional data is that the number of variables greatly exceeds the number of samples. Frequently the classifiers are developed using class-imbalanced data, i.e., data sets where the number of samples in each class is not equal. Standard classification methods used on class-imbalanced data often produce classifiers that do not accurately predict the minority class; the prediction is biased towards the majority class. In this paper we investigate if the high-dimensionality poses additional challenges when dealing with class-imbalanced prediction. We evaluate the performance of six types of classifiers on class-imbalanced data, using simulated data and a publicly available data set from a breast cancer gene-expression microarray study. We also investigate the effectiveness of some strategies that are available to overcome the effect of class imbalance. Results Our results show that the evaluated classifiers are highly sensitive to class imbalance and that variable selection introduces an additional bias towards classification into the majority class. Most new samples are assigned to the majority class from the training set, unless the difference between the classes is very large. As a consequence, the class-specific predictive accuracies differ considerably. When the class imbalance is not too severe, down-sizing and asymmetric bagging embedding variable selection work well, while over-sampling does not. Variable normalization can further worsen the performance of the classifiers. Conclusions Our results show that matching the prevalence of the classes in training and test set does not guarantee good performance of classifiers and that the problems related to classification with class

  7. As aulas de Educação Física na classe especial na abordagem psicomotora

    Directory of Open Access Journals (Sweden)

    Roberta Bevilaqua de Quadros

    2013-07-01

    Full Text Available http://dx.doi.org/10.5007/2175-8042.2013v25n40p41 O estudo baseia-se em um relato de experiência das aulas de Educação Física de uma turma de Classe Especial, visando demonstrar a importância desta disciplina como prática pedagógica, seguindo a abordagem psicomotora. A classe em questão era formada por seis crianças com necessidades educacionais especiais, e ocorriam duas vezes por semana, uma juntamente com uma turma de classe regular. Através do planejamento e execução das aulas constatou-se a importância do componente curricular educação física, pois os alunos vivenciaram atividades que privilegiaram a cooperação, criatividade e coletividade, refletindo no desenvolvimento motor, cognitivo, e afetivo-social.

  8. Stress Management in Physical Education Class: An Experiential Approach to Improve Coping Skills and Reduce Stress Perceptions in Adolescents

    Science.gov (United States)

    Lang, Christin; Feldmeth, Anna Karina; Brand, Serge; Holsboer-Trachsler, Edith; Pühse, Uwe; Gerber, Markus

    2016-01-01

    In most physical education (PE) syllabuses, promoting life skills constitutes an important educational objective. The aim of this study was to implement a coping training program (EPHECT) within regular PE and to evaluate its effects on coping and stress among vocational students. Eight classes from a vocational school were selected for study;…

  9. 26 CFR 1.1402(a)-18 - Split-dollar life insurance arrangements.

    Science.gov (United States)

    2010-04-01

    ... life insurance arrangements. See §§ 1.61-22 and 1.7872-15 for rules relating to the treatment of split-dollar life insurance arrangements. [T.D. 9092, 68 FR 54352, Sept. 17, 2003] ... 26 Internal Revenue 12 2010-04-01 2010-04-01 false Split-dollar life insurance arrangements. 1...

  10. Extending positive CLASS results across multiple instructors and multiple classes of Modeling Instruction

    Directory of Open Access Journals (Sweden)

    Eric Brewe

    2013-10-01

    Full Text Available We report on a multiyear study of student attitudes measured with the Colorado Learning Attitudes about Science Survey in calculus-based introductory physics taught with the Modeling Instruction curriculum. We find that five of six instructors and eight of nine sections using Modeling Instruction showed significantly improved attitudes from pre- to postcourse. Cohen’s d effect sizes range from 0.08 to 0.95 for individual instructors. The average effect was d=0.45, with a 95% confidence interval of (0.26–0.64. These results build on previously published results showing positive shifts in attitudes from Modeling Instruction classes. We interpret these data in light of other published positive attitudinal shifts and explore mechanistic explanations for similarities and differences with other published positive shifts.

  11. A retrospective study of Class II mixed-dentition treatment.

    Science.gov (United States)

    Oh, Heesoo; Baumrind, Sheldon; Korn, Edward L; Dugoni, Steven; Boero, Roger; Aubert, Maryse; Boyd, Robert

    2017-01-01

    To consider the effectiveness of early treatment using one mixed-dentition approach to the correction of moderate and severe Class II malocclusions. Three groups of Class II subjects were included in this retrospective study: an early treatment (EarlyTx) group that first presented at age 7 to 9.5 years (n = 54), a late treatment (LateTx) group whose first orthodontic visit occurred between ages 12 and 15 (n = 58), and an untreated Class II (UnTx) group to assess the pretreatment comparability of the two treated groups (n = 51). Thirteen conventional cephalometric measurements were reported for each group and Class II molar severity was measured on the study casts of the EarlyTx and LateTx groups. Successful Class II correction was observed in approximately three quarters of both the EarlyTx group and the LateTx group at the end of treatment. EarlyTx patients had fewer permanent teeth extracted than did the LateTx patients (5.6% vs 37.9%, P < .001) and spent less time in full-bonded appliance therapy in the permanent dentition than did LateTx patients (1.7 ± 0.8 vs 2.6 ± 0.7years, P < .001). When supervision time is included, the EarlyTx group had longer total treatment time and averaged more visits than did the LateTx group (53.1 ± 18. 8 vs 33.7 ± 8.3, P < .0001). Fifty-five percent of the LateTx extraction cases involved removal of the maxillary first premolars only and were finished in a Class II molar relationship. EarlyTx comprehensive mixed-dentition treatment was an effective modality for early correction of Class II malocclusions.

  12. Snacks, beverages, vending machines, and school stores: a comparison of alternative and regular schools in Minnesota, 2002 to 2008.

    Science.gov (United States)

    Kubik, Martha Y; Davey, Cynthia; MacLehose, Richard F; Coombes, Brandon; Nanney, Marilyn S

    2015-01-01

    In US secondary schools, vending machines and school stores are a common source of low-nutrient, energy-dense snacks and beverages, including sugar-sweetened beverages, high-fat salty snacks, and candy. However, little is known about the prevalence of these food practices in alternative schools, which are educational settings for students at risk of academic failure due to truancy, school expulsion, and behavior problems. Nationwide, more than 5,000 alternative schools enroll about one-half million students who are disproportionately minority and low-income youth. Principal survey data from a cross-sectional sample of alternative (n=104) and regular (n=339) schools collected biennially from 2002-2008 as part of the Centers for Disease Control and Prevention Minnesota School Health Profiles were used to assess and compare food practice prevalence over time. Generalized estimating equation models were used to estimate prevalence, adjusting for school demographics. Over time, food practice prevalence decreased significantly for both alternative and regular schools, although declines were mostly modest. However, the decrease in high-fat, salty snacks was significantly less for alternative than regular schools (-22.9% vs -42.2%; Pvending machines and school stores in alternative schools than regular schools, which may contribute to increased snacking behavior among students and extra consumption of salt, fat, and sugar. Study findings support the need to include alternative schools in future efforts that aim to reform the school food environment. Copyright © 2015 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  13. Acolhendo e atuando com alunos que apresentam paralisia cerebral na classe regular: a organização da escola Reveiving and working with pupils who present cerebral palsy in the regular classroom: school organization

    Directory of Open Access Journals (Sweden)

    Francisco Ricardo Lins Vieira de Melo

    2007-04-01

    Full Text Available Este estudo tem como objetivo situar aspectos relativos a uma análise empreendida em duas escolas regulares da cidade do Natal/RN, a respeito de como têm se organizado, do ponto de vista ambiental e pedagógico, para incluir o aluno com paralisia cerebral em seu contexto. Com base no objetivo proposto, foi realizado um estudo descritivo do tipo estudo de caso. A coleta de informações realizou-se através da observação e da entrevista semi-estruturada. Os dados foram analisados tomando por base cinco categorias: projeto políticopedagógico; programa de informação e sensibilização; apoio da direção escolar; recursos pedagógicos adaptados; adequação do ambiente físico. A partir dos resultados foi possível identificar, em relação à organização ambiental e pedagógica das escolas investigadas, que de uma maneira geral necessitam: priorizar a elaboração do projeto pedagógico, levando em consideração os princípios da educação inclusiva; investir na formação continuada e apoiar mais os professores em sua prática pedagógica; desenvolver programas de orientação à comunidade escolar com vistas a desmistificar preconceitos e informar sobre as potencialidades do aluno com paralisia cerebral; buscar parcerias junto a outros profissionais e convênios para aquisição de recursos pedagógicos e equipamentos específicos para favorecer o processo de ensino-aprendizagem desse alunado; adequar a estrutura física das escolas visando assegurar a acessibilidade e a autonomia do aluno com paralisia cerebral no ensino regular.This study aimed to point out aspects requiring analysis in two regular schools of the city of Natal/RN, as to organization requirements, from the point of view of context and pedagogy, so as to enable the inclusion of students with cerebral palsy. A descriptive study was carried out, using a case study format. Data was collected through observation and semi-structured interviews. The data was analyzed based

  14. Physical model of dimensional regularization

    Energy Technology Data Exchange (ETDEWEB)

    Schonfeld, Jonathan F.

    2016-12-15

    We explicitly construct fractals of dimension 4-ε on which dimensional regularization approximates scalar-field-only quantum-field theory amplitudes. The construction does not require fractals to be Lorentz-invariant in any sense, and we argue that there probably is no Lorentz-invariant fractal of dimension greater than 2. We derive dimensional regularization's power-law screening first for fractals obtained by removing voids from 3-dimensional Euclidean space. The derivation applies techniques from elementary dielectric theory. Surprisingly, fractal geometry by itself does not guarantee the appropriate power-law behavior; boundary conditions at fractal voids also play an important role. We then extend the derivation to 4-dimensional Minkowski space. We comment on generalization to non-scalar fields, and speculate about implications for quantum gravity. (orig.)

  15. Information-theoretic semi-supervised metric learning via entropy regularization.

    Science.gov (United States)

    Niu, Gang; Dai, Bo; Yamada, Makoto; Sugiyama, Masashi

    2014-08-01

    We propose a general information-theoretic approach to semi-supervised metric learning called SERAPH (SEmi-supervised metRic leArning Paradigm with Hypersparsity) that does not rely on the manifold assumption. Given the probability parameterized by a Mahalanobis distance, we maximize its entropy on labeled data and minimize its entropy on unlabeled data following entropy regularization. For metric learning, entropy regularization improves manifold regularization by considering the dissimilarity information of unlabeled data in the unsupervised part, and hence it allows the supervised and unsupervised parts to be integrated in a natural and meaningful way. Moreover, we regularize SERAPH by trace-norm regularization to encourage low-dimensional projections associated with the distance metric. The nonconvex optimization problem of SERAPH could be solved efficiently and stably by either a gradient projection algorithm or an EM-like iterative algorithm whose M-step is convex. Experiments demonstrate that SERAPH compares favorably with many well-known metric learning methods, and the learned Mahalanobis distance possesses high discriminability even under noisy environments.

  16. Fluctuations of quantum fields via zeta function regularization

    International Nuclear Information System (INIS)

    Cognola, Guido; Zerbini, Sergio; Elizalde, Emilio

    2002-01-01

    Explicit expressions for the expectation values and the variances of some observables, which are bilinear quantities in the quantum fields on a D-dimensional manifold, are derived making use of zeta function regularization. It is found that the variance, related to the second functional variation of the effective action, requires a further regularization and that the relative regularized variance turns out to be 2/N, where N is the number of the fields, thus being independent of the dimension D. Some illustrating examples are worked through. The issue of the stress tensor is also briefly addressed

  17. Surgical-orthodontic correction of a Class III dentofacial deformity

    Directory of Open Access Journals (Sweden)

    Raghu Devanna

    2010-01-01

    Full Text Available This case report describes the surgical-orthodontic treatment of a 26-year-old post-pubertal male patient with a Class III dentofacial deformity. In the pre-surgical orthodontic phase of treatment, a reverse overjet of 5.5 mm was created and arch compatibility was obtained. A mandibualr set back with BSSO was performed during surgery to restore ideal overjet, overbite, occlusion and optimal esthetics. After 1 year of treatment, the results remained stable.

  18. 2010 survey of energy resources. 22nd edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-11-15

    This, the 22nd edition of the World Energy Council's Survey of Energy Resources (SER), is the latest in a long series of reviews of the status of the world's major energy resources. It covers not only the fossil fuels but also the major types of traditional and novel sources of energy. The Survey is a flagship publication of the World Energy Council (WEC), prepared triennially and timed for release at each World Energy Congress. It is a unique document in that no entity other than the WEC compiles such wideranging information on a regular and consistent basis. This highly regarded publication is an essential tool for governments, industry, investors, NGOs and academia.

  19. 2010 survey of energy resources. 22nd edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-11-15

    This, the 22nd edition of the World Energy Council's Survey of Energy Resources (SER), is the latest in a long series of reviews of the status of the world's major energy resources. It covers not only the fossil fuels but also the major types of traditional and novel sources of energy. The Survey is a flagship publication of the World Energy Council (WEC), prepared triennially and timed for release at each World Energy Congress. It is a unique document in that no entity other than the WEC compiles such wideranging information on a regular and consistent basis. This highly regarded publication is an essential tool for governments, industry, investors, NGOs and academia.

  20. X-ray computed tomography using curvelet sparse regularization.

    Science.gov (United States)

    Wieczorek, Matthias; Frikel, Jürgen; Vogel, Jakob; Eggl, Elena; Kopp, Felix; Noël, Peter B; Pfeiffer, Franz; Demaret, Laurent; Lasser, Tobias

    2015-04-01

    Reconstruction of x-ray computed tomography (CT) data remains a mathematically challenging problem in medical imaging. Complementing the standard analytical reconstruction methods, sparse regularization is growing in importance, as it allows inclusion of prior knowledge. The paper presents a method for sparse regularization based on the curvelet frame for the application to iterative reconstruction in x-ray computed tomography. In this work, the authors present an iterative reconstruction approach based on the alternating direction method of multipliers using curvelet sparse regularization. Evaluation of the method is performed on a specifically crafted numerical phantom dataset to highlight the method's strengths. Additional evaluation is performed on two real datasets from commercial scanners with different noise characteristics, a clinical bone sample acquired in a micro-CT and a human abdomen scanned in a diagnostic CT. The results clearly illustrate that curvelet sparse regularization has characteristic strengths. In particular, it improves the restoration and resolution of highly directional, high contrast features with smooth contrast variations. The authors also compare this approach to the popular technique of total variation and to traditional filtered backprojection. The authors conclude that curvelet sparse regularization is able to improve reconstruction quality by reducing noise while preserving highly directional features.

  1. Semisupervised Support Vector Machines With Tangent Space Intrinsic Manifold Regularization.

    Science.gov (United States)

    Sun, Shiliang; Xie, Xijiong

    2016-09-01

    Semisupervised learning has been an active research topic in machine learning and data mining. One main reason is that labeling examples is expensive and time-consuming, while there are large numbers of unlabeled examples available in many practical problems. So far, Laplacian regularization has been widely used in semisupervised learning. In this paper, we propose a new regularization method called tangent space intrinsic manifold regularization. It is intrinsic to data manifold and favors linear functions on the manifold. Fundamental elements involved in the formulation of the regularization are local tangent space representations, which are estimated by local principal component analysis, and the connections that relate adjacent tangent spaces. Simultaneously, we explore its application to semisupervised classification and propose two new learning algorithms called tangent space intrinsic manifold regularized support vector machines (TiSVMs) and tangent space intrinsic manifold regularized twin SVMs (TiTSVMs). They effectively integrate the tangent space intrinsic manifold regularization consideration. The optimization of TiSVMs can be solved by a standard quadratic programming, while the optimization of TiTSVMs can be solved by a pair of standard quadratic programmings. The experimental results of semisupervised classification problems show the effectiveness of the proposed semisupervised learning algorithms.

  2. Regularity and chaos in cavity QED

    International Nuclear Information System (INIS)

    Bastarrachea-Magnani, Miguel Angel; López-del-Carpio, Baldemar; Chávez-Carlos, Jorge; Lerma-Hernández, Sergio; Hirsch, Jorge G

    2017-01-01

    The interaction of a quantized electromagnetic field in a cavity with a set of two-level atoms inside it can be described with algebraic Hamiltonians of increasing complexity, from the Rabi to the Dicke models. Their algebraic character allows, through the use of coherent states, a semiclassical description in phase space, where the non-integrable Dicke model has regions associated with regular and chaotic motion. The appearance of classical chaos can be quantified calculating the largest Lyapunov exponent over the whole available phase space for a given energy. In the quantum regime, employing efficient diagonalization techniques, we are able to perform a detailed quantitative study of the regular and chaotic regions, where the quantum participation ratio (P R ) of coherent states on the eigenenergy basis plays a role equivalent to the Lyapunov exponent. It is noted that, in the thermodynamic limit, dividing the participation ratio by the number of atoms leads to a positive value in chaotic regions, while it tends to zero in the regular ones. (paper)

  3. Cognitive Aspects of Regularity Exhibit When Neighborhood Disappears

    Science.gov (United States)

    Chen, Sau-Chin; Hu, Jon-Fan

    2015-01-01

    Although regularity refers to the compatibility between pronunciation of character and sound of phonetic component, it has been suggested as being part of consistency, which is defined by neighborhood characteristics. Two experiments demonstrate how regularity effect is amplified or reduced by neighborhood characteristics and reveals the…

  4. Major histocompatibility complex (MHC) class III genetics in two Amerindian tribes from southern Brazil: the Kaingang and the Guarani.

    Science.gov (United States)

    Weg-Remers, S; Brenden, M; Schwarz, E; Witzel, K; Schneider, P M; Guerra, L K; Rehfeldt, I R; Lima, M T; Hartmann, D; Petzl-Erler, M L; de Messias, I J; Mauff, G

    1997-10-01

    Population genetic studies of the major histocompatibility complex (MHC) class III region, comprising C2, BF and C4 phenotypes, and molecular genetic data are rarely available for populations other than Caucasoids. We have investigated three Amerindian populations from Southern Brazil: 131 Kaingang from Ivaí (KIV), 111 Kaingang (KRC) and 100 Guarani (GRC) from Rio das Cobras. Extended MHC haplotypes were derived after standard C2, BF, C4 phenotyping and restriction fragment length polymorphism (RFLP) analysis with TaqI, together with HLA data published previously by segregation analysis. C2 and BF frequencies corresponded to other Amerindian populations. C4B*Q0 frequency was high in the GRC (0.429) but low in the Kaingang. Unusual C4 alleles were found, viz. C4A*58, A*55 and C4B*22 (presumably non-Amerindian) and aberrant C4A*3 of Amerindian origin occurring with a frequency of 0.223 in the GRC. C4A*3 bands of homo- and heterozygous individuals carrying this variant were Rodgers 1 positive and Chido 1,3 positive, showed a C4A specific lysis type and a C4A like alpha-chain. Polymerase chain reaction studies and sequencing showed that this is based on a C4A*3 duplication with a regular C4A*3 and a partially converted C4A*0304 carrying the C4B specific epitopes Ch 6 and Ch 1,3. Associations of class III haplotypes with particular RFLP patterns were similar to those reported for Caucasoids. The previously described association between combined C4A and CYP21P deletions and the 6.4 kb TaqI fragment was not seen in these Amerindians. This fragment occurred within a regular two locus gene structure in the Kaingang, representing a "short" gene at C4 locus I. C4 and CYP21 duplications were frequently observed. The distribution of extended MHC haplotypes provides evidence for a close relationship between the KIV and KRC and a larger genetic distance between the two Kaingang groups and the GRC.

  5. Dependent Classes

    DEFF Research Database (Denmark)

    Gasiunas, Vaidas; Mezini, Mira; Ostermann, Klaus

    2007-01-01

    of dependent classes and a machine-checked type soundness proof in Isabelle/HOL [29], the first of this kind for a language with virtual classes and path-dependent types. [29] T.Nipkow, L.C. Poulson, and M. Wenzel. Isabelle/HOL -- A Proof Assistant for Higher-Order Logic, volume 2283 of LNCS, Springer, 2002......Virtual classes allow nested classes to be refined in subclasses. In this way nested classes can be seen as dependent abstractions of the objects of the enclosing classes. Expressing dependency via nesting, however, has two limitations: Abstractions that depend on more than one object cannot...... be modeled and a class must know all classes that depend on its objects. This paper presents dependent classes, a generalization of virtual classes that expresses similar semantics by parameterization rather than by nesting. This increases expressivity of class variations as well as the flexibility...

  6. Super spin-charge separation for class A, C and D disorder

    International Nuclear Information System (INIS)

    LeClair, Andre; Robinson, Dean J

    2008-01-01

    We prove versions of super spin-charge separation for all three of the symmetry groups SU(N), Sp(2N) and SO(N) of disordered Dirac fermions in 2 + 1 dimensions, which involve the supercurrent algebras gl(1|1) N ,osp(2|2) -2N and osp(2|2) N respectively. For certain restricted classes of disordered potentials, the latter supercurrent algebra based conformal field theories can arise as non-trivial low energy fixed points. For all cases with such a fixed point, we compute the density of states exponents as a function of N. (fast track communication)

  7. An adaptive regularization parameter choice strategy for multispectral bioluminescence tomography

    Energy Technology Data Exchange (ETDEWEB)

    Feng Jinchao; Qin Chenghu; Jia Kebin; Han Dong; Liu Kai; Zhu Shouping; Yang Xin; Tian Jie [Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, P. O. Box 2728, Beijing 100190 (China); College of Electronic Information and Control Engineering, Beijing University of Technology, Beijing 100124 (China); Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, P. O. Box 2728, Beijing 100190 (China); Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, P. O. Box 2728, Beijing 100190 (China) and School of Life Sciences and Technology, Xidian University, Xi' an 710071 (China)

    2011-11-15

    Purpose: Bioluminescence tomography (BLT) provides an effective tool for monitoring physiological and pathological activities in vivo. However, the measured data in bioluminescence imaging are corrupted by noise. Therefore, regularization methods are commonly used to find a regularized solution. Nevertheless, for the quality of the reconstructed bioluminescent source obtained by regularization methods, the choice of the regularization parameters is crucial. To date, the selection of regularization parameters remains challenging. With regards to the above problems, the authors proposed a BLT reconstruction algorithm with an adaptive parameter choice rule. Methods: The proposed reconstruction algorithm uses a diffusion equation for modeling the bioluminescent photon transport. The diffusion equation is solved with a finite element method. Computed tomography (CT) images provide anatomical information regarding the geometry of the small animal and its internal organs. To reduce the ill-posedness of BLT, spectral information and the optimal permissible source region are employed. Then, the relationship between the unknown source distribution and multiview and multispectral boundary measurements is established based on the finite element method and the optimal permissible source region. Since the measured data are noisy, the BLT reconstruction is formulated as l{sub 2} data fidelity and a general regularization term. When choosing the regularization parameters for BLT, an efficient model function approach is proposed, which does not require knowledge of the noise level. This approach only requests the computation of the residual and regularized solution norm. With this knowledge, we construct the model function to approximate the objective function, and the regularization parameter is updated iteratively. Results: First, the micro-CT based mouse phantom was used for simulation verification. Simulation experiments were used to illustrate why multispectral data were used

  8. Cu e Zn na cultura do sorgo cultivado em três classes de solos: I. Crescimento vegetativo e produção Cu and Zn in sorghum cultivated in three soil classes: I. Vegetative growth and yield

    Directory of Open Access Journals (Sweden)

    Hemmannuella C. Santos

    2009-04-01

    Full Text Available Os micronutrientes Cu e Zn são importantes para o bom desenvolvimento vegetativo e para a formação de grãos em cereais. Com o objetivo de avaliar o efeito da aplicação de Cu e Zn nos atributos de crescimento e na produção da cultura do sorgo realizou-se um experimento em ambiente protegido, no qual o delineamento foi em blocos casualizados, com a combinação de cinco doses de cobre (0, 0,26, 0,90, 1,54 e 1,80 mg kg-1 e cinco doses de zinco (0, 0,32, 1,1, 1,88 e 2,2 mg kg-1, combinadas na matriz Composto Central de Box, perfazendo 9 tratamentos, que foram aplicados em três classes de solo (Latossolo, Luvissolo e Neossolo, com 3 repetições. Avaliaram-se, aos 96 dias após a semeadura, os atributos de crescimento e a produção da cultura. A aplicação de cobre resultou em incrementos na área foliar, diâmetro do colmo, comprimento e diâmetro da panícula, matéria seca e na produção, o mesmo não ocorrendo para o zinco. As concentrações foliares de zinco indicaram interação negativa entre as doses aplicadas, enquanto entre os solos o Luvissolo foi o mais responsivo à aplicação dos nutrientes.The micronutrients copper and zinc are important for good vegetative growth and for grain formation in cereals. An experiment was carried out aiming to evaluate the effect of copper and zinc application upon growth attributes of sorghum and upon its grain yield. A randomized block experimental design was used, with a combination of five doses of copper (0, 0.26, 0.90, 1.54 and 1.80 mg kg-1 and five doses of zinc (0, 0.32, 1.1, 1.88 and 2.2 mg kg-1 combined by Box Central Composite design, resulting in nine treatments which were applied in three soil classes (Latosol, Alfisol and Entisol, with three replications. Ninety six days after sowing, growth attributes and sorghum yield were determined. The copper application increased leaf area, stem diameter, panicle length and diameter, dry matter yield and grain yield, however the same

  9. 26 CFR 1.338-6 - Allocation of ADSP and AGUB among target assets.

    Science.gov (United States)

    2010-04-01

    ... allocated among Class II acquisition date assets of target in proportion to the fair market values of such... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Allocation of ADSP and AGUB among target assets... among target assets. (a) Scope—(1) In general. This section prescribes rules for allocating ADSP and...

  10. 26 CFR 1.936-6 - Intangible property income when an election out is made: Cost sharing and profit split options...

    Science.gov (United States)

    2010-04-01

    ... corporation any class of the stock of which is regularly traded on an established securities market, then the... the taxpayer or other members of an affiliated group which includes the taxpayer produce and market...: chewing gum and granulated sugar (SIC code 206); canned tuna fish and freeze-dried coffee (SIC code 209...

  11. 75 FR 42014 - Proposed Amendment of Class E Airspace; San Clemente, CA

    Science.gov (United States)

    2010-07-20

    ...: Eldon Taylor, Federal Aviation Administration, Operations Support Group, Western Service Center, 1601... an extension to a Class D surface area, at San Clemente Island NALF (Fredrick Sherman Field), San... Clemente Island NALF (Fredrick Sherman Field), CA (Lat. 33[deg]01'22'' N., long. 118[deg]35'19'' W.) San...

  12. Ideologies Revealed During the Construction of Meaning in an EFL Class

    Directory of Open Access Journals (Sweden)

    Néstor Ricardo Fajardo Mora

    2014-10-01

    Full Text Available This article reports on an interpretive qualitative study conducted at a public university in Bogotá with 26 pre-service social studies teachers. It is focused on unveiling which ideologies are discovered when they construct the meaning of texts through text-based tasks in an English as a foreign language class. The data were collected by using class video recordings and students’ artifacts. The data analysis procedure follows an inductive process based on grounded theory. Results indicated three subsidiary categories called Shattering the Establishment, Perspectives From a Counter-Hegemonic Position, and Resisting the Mainstream. Furthermore, there is the core category Habitus, which assembles those subsidiary categories in an internalized system of fixed dispositions.

  13. [Myocardial infarction in a 26-year-old patient with diabetes type 1].

    Science.gov (United States)

    Rogowicz, Anita; Zozulińska, Dorota; Wierusz-Wysocka, Bogna

    2007-11-01

    A case of a 26-year-old patient with acute myocardial infarction and hypertension, hyperlipidaemia as well as type 1 diabetes from 18 years complicated by background retinopathy and nephropathy in the state of proteinuria is described. State of metabolic compensation of the diabetes was poor. The patient did not perform regular self-monitoring of glycaemia, smoked, and used oral contraception. Early diagnosis of vascular lesions in young persons with long-lasting of type 1 diabetes as well as the introduction of proper preventive and treatment methods may improve prognosis in these high-risk patients.

  14. On the Spatial Distribution of High Velocity Al-26 Near the Galactic Center

    Science.gov (United States)

    Sturner, Steven J.

    2000-01-01

    We present results of simulations of the distribution of 1809 keV radiation from the decay of Al-26 in the Galaxy. Recent observations of this emission line using the Gamma Ray Imaging Spectrometer (GRIS) have indicated that the bulk of the AL-26 must have a velocity of approx. 500 km/ s. We have previously shown that a velocity this large could be maintained over the 10(exp 6) year lifetime of the Al-26 if it is trapped in dust grains that are reaccelerated periodically in the ISM. Here we investigate whether a dust grain velocity of approx. 500 km/ s will produce a distribution of 1809 keV emission in latitude that is consistent with the narrow distribution seen by COMPTEL. We find that dust grain velocities in the range 275 - 1000 km/ s are able to reproduce the COMPTEL 1809 keV emission maps reconstructed using the Richardson-Lucy and Maximum Entropy image reconstruction methods while the emission map reconstructed using the Multiresolution Regularized Expectation Maximization algorithm is not well fit by any of our models. The Al-26 production rate that is needed to reproduce the observed 1809 keV intensity yields in a Galactic mass of Al-26 of approx. 1.5 - 2 solar mass which is in good agreement with both other observations and theoretical production rates.

  15. Matrix regularization of embedded 4-manifolds

    International Nuclear Information System (INIS)

    Trzetrzelewski, Maciej

    2012-01-01

    We consider products of two 2-manifolds such as S 2 ×S 2 , embedded in Euclidean space and show that the corresponding 4-volume preserving diffeomorphism algebra can be approximated by a tensor product SU(N)⊗SU(N) i.e. functions on a manifold are approximated by the Kronecker product of two SU(N) matrices. A regularization of the 4-sphere is also performed by constructing N 2 ×N 2 matrix representations of the 4-algebra (and as a byproduct of the 3-algebra which makes the regularization of S 3 also possible).

  16. Optimal Tikhonov Regularization in Finite-Frequency Tomography

    Science.gov (United States)

    Fang, Y.; Yao, Z.; Zhou, Y.

    2017-12-01

    The last decade has witnessed a progressive transition in seismic tomography from ray theory to finite-frequency theory which overcomes the resolution limit of the high-frequency approximation in ray theory. In addition to approximations in wave propagation physics, a main difference between ray-theoretical tomography and finite-frequency tomography is the sparseness of the associated sensitivity matrix. It is well known that seismic tomographic problems are ill-posed and regularizations such as damping and smoothing are often applied to analyze the tradeoff between data misfit and model uncertainty. The regularizations depend on the structure of the matrix as well as noise level of the data. Cross-validation has been used to constrain data uncertainties in body-wave finite-frequency inversions when measurements at multiple frequencies are available to invert for a common structure. In this study, we explore an optimal Tikhonov regularization in surface-wave phase-velocity tomography based on minimization of an empirical Bayes risk function using theoretical training datasets. We exploit the structure of the sensitivity matrix in the framework of singular value decomposition (SVD) which also allows for the calculation of complete resolution matrix. We compare the optimal Tikhonov regularization in finite-frequency tomography with traditional tradeo-off analysis using surface wave dispersion measurements from global as well as regional studies.

  17. 22 CFR 228.22 - Air transportation.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Air transportation. 228.22 Section 228.22... for USAID Financing § 228.22 Air transportation. (a) The eligibility of air transportation is... U.S. flag air carriers for all international air travel and transportation, unless such service is...

  18. Fractional Regularization Term for Variational Image Registration

    Directory of Open Access Journals (Sweden)

    Rafael Verdú-Monedero

    2009-01-01

    Full Text Available Image registration is a widely used task of image analysis with applications in many fields. Its classical formulation and current improvements are given in the spatial domain. In this paper a regularization term based on fractional order derivatives is formulated. This term is defined and implemented in the frequency domain by translating the energy functional into the frequency domain and obtaining the Euler-Lagrange equations which minimize it. The new regularization term leads to a simple formulation and design, being applicable to higher dimensions by using the corresponding multidimensional Fourier transform. The proposed regularization term allows for a real gradual transition from a diffusion registration to a curvature registration which is best suited to some applications and it is not possible in the spatial domain. Results with 3D actual images show the validity of this approach.

  19. Reducing errors in the GRACE gravity solutions using regularization

    Science.gov (United States)

    Save, Himanshu; Bettadpur, Srinivas; Tapley, Byron D.

    2012-09-01

    The nature of the gravity field inverse problem amplifies the noise in the GRACE data, which creeps into the mid and high degree and order harmonic coefficients of the Earth's monthly gravity fields provided by GRACE. Due to the use of imperfect background models and data noise, these errors are manifested as north-south striping in the monthly global maps of equivalent water heights. In order to reduce these errors, this study investigates the use of the L-curve method with Tikhonov regularization. L-curve is a popular aid for determining a suitable value of the regularization parameter when solving linear discrete ill-posed problems using Tikhonov regularization. However, the computational effort required to determine the L-curve is prohibitively high for a large-scale problem like GRACE. This study implements a parameter-choice method, using Lanczos bidiagonalization which is a computationally inexpensive approximation to L-curve. Lanczos bidiagonalization is implemented with orthogonal transformation in a parallel computing environment and projects a large estimation problem on a problem of the size of about 2 orders of magnitude smaller for computing the regularization parameter. Errors in the GRACE solution time series have certain characteristics that vary depending on the ground track coverage of the solutions. These errors increase with increasing degree and order. In addition, certain resonant and near-resonant harmonic coefficients have higher errors as compared with the other coefficients. Using the knowledge of these characteristics, this study designs a regularization matrix that provides a constraint on the geopotential coefficients as a function of its degree and order. This regularization matrix is then used to compute the appropriate regularization parameter for each monthly solution. A 7-year time-series of the candidate regularized solutions (Mar 2003-Feb 2010) show markedly reduced error stripes compared with the unconstrained GRACE release 4

  20. ZZ RRDF-98, Cross-sections and covariance matrices for 22 neutron induced dosimetry reactions

    International Nuclear Information System (INIS)

    Zolotarev, K.I.; Ignatyuk, A.V.; Mahokhin, V.N.; Pashchenko, A.B.

    2005-01-01

    1 - Description of program or function: Format: ENDF-6 format; Number of groups: Continuous energy; Dosimetry reactions: 6-C-12(n,2n), 8-O-16(n,2n), 9-F-19(n,2n), 12-Mg-24(n,p), 22-Ti-46(n,2n), 22-Ti-46(n,p), 22-Ti-47(n,x), 22-Ti-48(n,p), 22-Ti-48(n,x), 22-Ti-49(n,x), 23-V-51(n,alpha), 26-Fe-54(n,2n), 26-Fe-54(n,alpha), 26-Fe-56(n,p), 27-Co-59(n,alpha), 29-Cu-63(n,alpha), 33-As-75(n,2n), 41-Nb-93(n,2n), 41-Nb-93(n,n'), 45-Rh-103(n,n'), 49-In-115(n,n'), 59-Pr-141(n,2n); Origin: Russian Federation; Weighting spectrum: None. RRDF-98 contains original evaluations of cross section data performed at the Institute of Physics and Power Engineering, Obninsk, for 22 neutron induced dosimetry reactions. The dataset also contains the corresponding covariance matrices. 2 - Methods: The evaluation of excitation functions was performed on the basis of statistical analysis of corrected experimental data in the framework of generalized least squares method and taking into account the results of optical-statistical STAPRE and GNASH calculations. The experimental cross section data including the most recent results were critically reviewed and processed in this study. If necessary, the data were normalized in order to make adjustments in relevant cross sections and decay schemes. The covariance matrices were prepared and the evaluated cross section data are presented in ENDF-6 format (Files 3, 33). For estimation of correlations between experimental data the total uncertainties of measured cross sections have been separated into statistical and systematic parts and correlation coefficients between components of systematic parts were assigned according to information given in the original publications and EXFOR library. Then the correlation matrix of cross sections measured within one experiment was calculated and approximated by matrix with a constant (average) correlation coefficient. The overall correlation matrix was composed of such sub-matrices in the assumption that the cross