WorldWideScience

Sample records for regius boa constrictor

  1. Ultrasonographic anatomy of the coelomic organs of boid snakes (Boa constrictor imperator, Python regius, Python molurus molurus, and Python curtus).

    Science.gov (United States)

    Banzato, Tommaso; Russo, Elisa; Finotti, Luca; Milan, Maria C; Gianesella, Matteo; Zotti, Alessandro

    2012-05-01

    To determine the ultrasonographic features of the coelomic organs of healthy snakes belonging to the Boidae and Pythonidae families. 16 ball pythons (Python regius; 7 males, 8 females, and 1 sexually immature), 10 Indian rock pythons (Python molurus molurus; 5 males, 4 females, and 1 sexually immature), 12 Python curtus (5 males and 7 females), and 8 boa constrictors (Boa constrictor imperator; 4 males and 4 females). All snakes underwent complete ultrasonographic evaluation of the coelomic cavity; chemical restraint was not necessary. A dorsolateral approach to probe placement was chosen to increase image quality and to avoid injury to the snakes and operators. Qualitative and quantitative observations were recorded. The liver, stomach, gallbladder, pancreas, small and large intestines, kidneys, cloaca, and scent glands were identified in all snakes. The hemipenes were identified in 10 of the 21 (48%) male snakes. The spleen was identified in 5 of the 46 (11%) snakes, and ureters were identified in 6 (13%). In 2 sexually immature snakes, the gonads were not visible. One (2%) snake was gravid, and 7 (15%) had small amounts of free fluid in the coelomic cavity. A significant positive correlation was identified between several measurements (diameter and thickness of scent glands, gastric and pyloric walls, and colonic wall) and body length (snout to vent) and body weight. The study findings can be used as an atlas of the ultrasonographic anatomy of the coelomic cavity in healthy boid snakes. Ultrasonography was reasonably fast to perform and was well tolerated in conscious snakes.

  2. Computed tomography of the lung of healthy snakes of the species Python regius, Boa constrictor, Python reticulatus, Morelia viridis, Epicrates cenchria, and Morelia spilota.

    Science.gov (United States)

    Pees, Michael; Kiefer, Ingmar; Thielebein, Jens; Oechtering, Gerhard; Krautwald-Junghanns, Maria-Elisabeth

    2009-01-01

    Thirty-nine healthy boid snakes representing six different species (Python regius, Boa constrictor, Python reticulatus, Morelia viridis, Epicrates cenchria, and Morelia spilota) were examined using computed tomography (CT) to characterize the normal appearance of the respiratory tissue. Assessment was done subjectively and densitometry was performed using a defined protocol. The length of the right lung was calculated to be 11.1% of the body length, without a significant difference between species. The length of the left lung in proportion to the right was dependent on the species examined. The most developed left lung was in P. regius (81.2%), whereas in B. constrictor, the left lung was vestigial or absent (24.7%). A median attenuation of -814.6 HU and a variability of 45.9 HU were calculated for all species with no significant difference between species. Within the species, a significantly higher attenuation was found for P. regius in the dorsal and cranial aspect of the lung compared with the ventral and caudal part. In B. constrictor, the reduced left lung was significantly hyperattenuating compared with the right lung. Results of this study emphasize the value of CT and provide basic reference data for assessment of the snake lung in these species. Veterinary Radiology &

  3. Boa constrictor (Boa constrictor): foraging behavior

    Science.gov (United States)

    Sorrell, G.G.; Boback, M.S.; Reed, R.N.; Green, S.; Montgomery, Chad E.; DeSouza, L.S.; Chiaraviglio, M.

    2011-01-01

    Boa constrictor is often referred to as a sit-and-wait or ambush forager that chooses locations to maximize the likelihood of prey encounters (Greene 1983. In Janzen [ed.], Costa Rica Natural History, pp. 380-382. Univ. Chicago Press, Illinois). However, as more is learned about the natural history of snakes in general, the dichotomy between active versus ambush foraging is becoming blurred. Herein, we describe an instance of diurnal active foraging by a B. constrictor, illustrating that this species exhibits a range of foraging behaviors.

  4. Mandibular osteosynthesis in a Boa constrictor snake

    Directory of Open Access Journals (Sweden)

    Jorge Luiz Costa Castro

    2014-02-01

    Full Text Available Nowadays are observed an increase in the finding of certain wild animals in urban areas, due to environmental changes caused by deforestation and economic use of natural areas. It causes disappearance of usual prey and forces these animals, including snakes, to migrate to urban areas, becoming vulnerable to injuries caused by aggressions, car accidents and capture. Mandibular and maxillar fractures are common in many animal species, representing about 3-6% of all bone fractures in dogs and cats. Mandibular trauma usually occurs as a result of fights, car accidents and improper handling and/or restraint, and fractures can be closed or open, clean or contaminated. The jaw is a flat bone with differences from the long bones that should be taken into consideration for successful treatment, being minimal muscle coverage and need to maintain occlusion factors that influence the definition of the best ostheosynthesis method. The methods of stabilization include using intramedullary pins, wires, external skeletal fixation, bone plate, and acrylic resin. Conventional bone plates are efficient but related to some complications, such as the necessity of muscular elevation and high risk of injuries to mandibular structures. This article describes the successful results of the application of plate and screws in the ostheosynthesis of a mandibular fracture in a female Boa constrictor snake with weight of 8.0 kg and length of 1.80 m, at the RIOZOO Foundation (Rio de Janeiro, RJ, Brazil.

  5. Osteopetrosis and osteonecrosis in snake Boa constrictor Osteopetrose e osteocondrose em serpente Boa constrictor

    Directory of Open Access Journals (Sweden)

    N.M. Ocarino

    2008-10-01

    Full Text Available Uma jibóia (Boa constrictor, de onze anos de cativeiro, apresentou à seis meses um histórico de aumento de volume ao longo da coluna vertebral e perda progressiva dos movimentos e de apetite. Exames radiológicos revelaram aumento da opacidade, áreas de excrescências ósseas e inúmeras fraturas ao longo da coluna. Devido o prognóstico desfavorável, a serpente foi eutanasiada. À necropsia, aumento de volume com estenose do canal vertebral e compressão da medula espinhal foram observados, juntamente com fraturas completas de corpos vertebrais. O diagnóstico de osteopetrose e osteonecrose foi firmado à histologia.

  6. Seasonal variation of serum biochemical values of Amazonian snakes (Boa constrictor constrictor kept in captivity

    Directory of Open Access Journals (Sweden)

    Dennis José da Silva Lima

    2012-11-01

    Full Text Available In northern Brazil, the seasons are not well defined compared to the South and Southeast regions, due to a hot and humid equatorial climate with a rainy season, known as the Amazonian winter, and a period with less rain, known as the Amazonian summer. The goal of this study was to evaluate the biochemical variation of serum from the Amazon Boa constrictor by correlating the values with the seasons of the region. A biochemical analysis of the serum was performed (AST, ALT, LDH, ALP, calcium, uric acid, phosphorus, total protein, albumin and globulin using 31 individuals of Boa constrictor constrictor, which were kept in captivity. It was observed that eight of the ten parameters were higher in the winter compared to the summer (total protein, albumin, globulin, ALT, AST, ALP, LDH and calcium. The ALT, AST and calcium values had statistically significant differences for the summer and winter, while the other parameters appear to be influenced by seasonality. This was the first study of snakes kept in captivity that analyzed the serum chemistry profile of Boa constrictor constrictor from the state of Pará, Brazil.

  7. Valores bioquímicos de jiboia (Boa constrictor

    Directory of Open Access Journals (Sweden)

    Kalena Barros da Silva

    2013-12-01

    Full Text Available Foram determinados os valores médios dos indicadores bioquímicos sanguíneos: glicose, ureia, creatinina, aspartato aminotransferase (AST, alanina aminotransferase (ALT, amilase e lipase de jiboias (Boa constrictor e comparados os valores das concentrações encontradas entre os grupos de machos e fêmeas. Foram utilizados 12 espécimes de Boa constrictor, dos quais sete machos e cinco fêmeas. A comparação das médias dos indicadores bioquímicos entre os grupos de machos e fêmeas indicou ausência de influência significativa de fatores sexuais. As técnicas bioquímicas tradicionais foram adequadas para a determinação desses indicadores para esta espécie.

  8. Ultrasound and computed tomography description of the liver the Boa constrictor; Descricao ultrassonografica e tomografica do figado de Boa constrictor

    Energy Technology Data Exchange (ETDEWEB)

    Zulim, Rosalia Marina Infiesta; Geller, Felipe Foletto; Souza, Priscila Macedo de; Mamprim, Maria Jaqueline, E-mail: rosaliamarina@hotmail.com [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucatu, SP (Brazil). Faculdade de Medicina Veterinaria e Zootecnia . Dept. de Reproducao Animal e Radiologia Veterinaria; Cardoso, Guilherme Schiess; Teixeira, Carlos Roberto [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucatu, SP (Brazil). Faculdade de Medicina Veterinaria e Zootecnia . Dept. de Cirurgia e Anestesiologia Veterinaria; Andrade, Rafael Souza [Universidade Federal Rural da Amazonia (UFRA), Belem, PA (Brazil); Rossetti, Diogo Pascoal; Comerlato, Alexandra Tiso [Universidade Estadual Paulista Julio de Mesquita Filho (CEMPAS/UNESP), Botucatu, SP (Brazil). Faculdade de Medicina Veterinaria e Zootecnia. Centro de Medicina e Pesquisa de Animais Silvestres

    2012-07-01

    Ultrasound is a method for noninvasive diagnosis, their effectiveness in the diagnosis of liver disease has been described in snakes. The liver is the largest organ of the coelomic cavity of reptiles. Elongated and flattened. The caudal vena cava and portal vein divides the body into two lobes. The hepatic parenchyma is homogeneous hypoechoic echogenicity. The objective is to describe and to obtain reference images in the study of liver four snakes of Boa constrictor amarali, through an ultrasound and tomography. Physical restraint made for the ultrasound examination held in prone position, to compare the texture and mark the structures for the slices on CT. A linear multifrequency probe of 6-10 mHz was used. The anesthetic protocol for computed tomography consisted of isoflurane. In helical CT scanner, the animal was positioned in the prone position, and used continuous cross sections of 2 mm by 2. The ultrasound and CT examinations allowed the identification of liver contours as well as the definition and extension of the caudal vena cava and portal vein. Normal pattern recognition of CT aspect of the present study will be of help in the diagnosis of liver diseases in snakes (Boa constrictor amarali). (author)

  9. Chemosensory age discrimination in the snake Boa constrictor (Serpentes: Boidae

    Directory of Open Access Journals (Sweden)

    Marianne Gabirot

    2012-12-01

    Full Text Available Many snakes are able to use their chemosensory system to detect scent of conspecifics, which is important in many social contexts. Age discrimination based on chemical cues may be especially important to ensure access to sexually mature potential partners. In this study, we used 24 individual Boa constrictor snakes (12 adults mature and 12 non-mature individuals that had been captured in different areas of Ecuador, and were maintained in captivity at the Vivarium of Quito. We used tongue-flick experiments to examine whether these snakes were able to discriminate between scents from mature and non-mature individuals. Results showed that B. constrictor snakes used chemical cues to recognize conspecifics and that the scent of individuals of different ages elicited chemosensory responses of different magnitudes. The scents from adult conspecifics elicited the quickest and highest chemosensory responses (i.e., short latency times and high tongue-flick rates, although we did not find differential responses to scent of males and females. The magnitude of the responses was lower to scent of sub adult individuals, and then even lower to scent of juvenile snakes, but in all cases the scent of snakes was discriminated from a blank control. We discuss the potential chemical mechanisms that may allow age recognition and its implications for social and sexual behavior of this snake species.

  10. Chemosensory age discrimination in the snake Boa constrictor (Serpentes: Boidae

    Directory of Open Access Journals (Sweden)

    Marianne Gabirot

    2012-12-01

    Full Text Available Many snakes are able to use their chemosensory system to detect scent of conspecifics, which is important in many social contexts. Age discrimination based on chemical cues may be especially important to ensure access to sexually mature potential partners. In this study, we used 24 individual Boa constrictor snakes (12 adults mature and 12 non-mature individuals that had been captured in different areas of Ecuador, and were maintained in captivity at the Vivarium of Quito. We used tongue-flick experiments to examine whether these snakes were able to discriminate between scents from mature and non-mature individuals. Results showed that B. constrictor snakes used chemical cues to recognize conspecifics and that the scent of individuals of different ages elicited chemosensory responses of different magnitudes. The scents from adult conspecifics elicited the quickest and highest chemosensory responses (i.e., short latency times and high tongue-flick rates, although we did not find differential responses to scent of males and females. The magnitude of the responses was lower to scent of sub adult individuals, and then even lower to scent of juvenile snakes, but in all cases the scent of snakes was discriminated from a blank control. We discuss the potential chemical mechanisms that may allow age recognition and its implications for social and sexual behavior of this snake species.Muchas serpientes son capaces de usar su sistema quimiosensorial para detectar el olor de individuos coespecíficos, lo que es importante en muchos contextos sociales. La discriminación de la edad basada en señales químicas puede ser especialmente importante para asegurar el acceso a parejas potenciales que sean sexualmente maduras. En este estudio, usamos 24 individuos de una especie de boa (Boa constrictor (12 individuos adultos y 12 inmaduros que habían sido capturados en diferentes partes de Ecuador y eran mantenidos en cautividad el Vivarium de Quito. Usamos

  11. Consumption of an adult Puma yagouaroundi (Felidae by the snake Boa constrictor (Boidae in Central Mexico Consumo de un jaguarundi adulto Puma yagouaroundi (Felidae por la serpiente Boa constrictor (Boidae en el centro de México

    Directory of Open Access Journals (Sweden)

    Octavio Monroy-Vilchis

    2011-03-01

    Full Text Available Few felids have been recorded as being preyed upon by the Boa constrictor snake (Boa constrictor. Documentation of predation on felids by reptiles is scarce, and natural predators of the adult jaguarundi (Puma yagouaroundi are poorly known. Here, we report for the first time an adult male jaguarundi being eaten by the snake Boa constrictor (of 273 cm snout-to-vent length at the Sierra Nanchititla Natural Reserve, Estado de México.Pocos depredadores han sido registrados como presas de la Boa constrictor (Boa constrictor. La depredación de felinos por reptiles es escasamente documentada y los depredadores naturales del jaguarundi (Puma yagouaroundi son pobremente conocidos. Aquí, nosotros informamos de un evento de depredación de un jaguarundi macho adulto que fue consumido por una B. constrictor (longitud hocico-cloaca: 273 cm en la Reserva Natural Sierra Nanchititla, Estado de México.

  12. Amblyomma dissimile (Acari: Ixodidae PARÁSITO DE Boa constrictor EN COLOMBIA

    Directory of Open Access Journals (Sweden)

    Ana Torres M

    2009-08-01

    Full Text Available Objetivo. Describir algunas garrapatas encontradas en dos ejemplares de Boa constrictor, llevados al Centro de Atención y Valoración de Fauna Silvestre en Montería, Córdoba, Colombia. Materiales y métodos. Se recolectaron 37 garrapatas provenientes de dos individuos adultos de Boa constrictor, los parásitos fueron conservados en alcohol al 70% y posteriormente identificados mediante diversas claves taxonómicas. Resultados. Todas las garrapatas fueron identificadas como Amblyomma dissimile, de las cuales, 9 fueron hembras, 24 machos y 4 ninfas. Conclusiones. La identificación de ectoparásitos en especies de Boa c. constrictor contribuye a mantener adecuadamente esta especie en cautiverio y provee datos para establecer medidas profilácticas y tratamiento, igualmente, ayuda en el conocimiento de los agentes parasitarios de la fauna silvestre.

  13. Death of Boa constrictor amarali (serpentes, boidae after ingestion of a tree porcupine (rodentia

    Directory of Open Access Journals (Sweden)

    A. L. Cherubini

    2003-01-01

    Full Text Available The objective of this paper is to report the death of a Boa constrictor amarali after ingestion of a tree porcupine. The animal was donated to the Center for the Study of Venoms and Venomous Animals (CEVAP/UNESP - and died in captivity. At necropsy, spine-like structures were observed in the stomach serosa and vicinity, and the stomach mucosa showed an intense reddish area, suggesting inflammation. The analysis of the spine-like structure revealed that they were tree porcupine spines. The feeding habits and inexperience of this Boa constrictor amarali in selecting its prey may have been be responsible for its death.

  14. New record of Boa constrictor occidentalis Philippi, 1873 (Serpentes: Boidae) in San Juan province, Argentina

    OpenAIRE

    Martínez, Tomás; Rodriguez Muñoz, Melina; Galdeano, Ana; Acosta, Juan

    2015-01-01

    We document the first record of Boa constrictor in Valle Fértil department, San Juan province, Argentina. The specimen was collected and deposited in the herpetological collection of the Department of Biology, Universidad Nacional San Juan. This record extends the known distribution for this species in San Juan province by 105 km.

  15. Differential Disease Susceptibilities in Experimentally Reptarenavirus-Infected Boa Constrictors and Ball Pythons

    Science.gov (United States)

    Sanchez-Migallon Guzman, David; Garcia, Valentina E.; Layton, Marylee L.; Hoon-Hanks, Laura L.; Boback, Scott M.; Keel, M. Kevin; Drazenovich, Tracy

    2017-01-01

    ABSTRACT Inclusion body disease (IBD) is an infectious disease originally described in captive snakes. It has traditionally been diagnosed by the presence of large eosinophilic cytoplasmic inclusions and is associated with neurological, gastrointestinal, and lymphoproliferative disorders. Previously, we identified and established a culture system for a novel lineage of arenaviruses isolated from boa constrictors diagnosed with IBD. Although ample circumstantial evidence suggested that these viruses, now known as reptarenaviruses, cause IBD, there has been no formal demonstration of disease causality since their discovery. We therefore conducted a long-term challenge experiment to test the hypothesis that reptarenaviruses cause IBD. We infected boa constrictors and ball pythons by cardiac injection of purified virus. We monitored the progression of viral growth in tissues, blood, and environmental samples. Infection produced dramatically different disease outcomes in snakes of the two species. Ball pythons infected with Golden Gate virus (GoGV) and with another reptarenavirus displayed severe neurological signs within 2 months, and viral replication was detected only in central nervous system tissues. In contrast, GoGV-infected boa constrictors remained free of clinical signs for 2 years, despite high viral loads and the accumulation of large intracellular inclusions in multiple tissues, including the brain. Inflammation was associated with infection in ball pythons but not in boa constrictors. Thus, reptarenavirus infection produces inclusions and inclusion body disease, although inclusions per se are neither necessarily associated with nor required for disease. Although the natural distribution of reptarenaviruses has yet to be described, the different outcomes of infection may reflect differences in geographical origin. IMPORTANCE New DNA sequencing technologies have made it easier than ever to identify the sequences of microorganisms in diseased tissues, i

  16. Potentiation of aminoglycoside antibiotic activity using the body fat from the snake Boa constrictor

    Directory of Open Access Journals (Sweden)

    Felipe S. Ferreira

    2011-05-01

    Full Text Available Boa constrictor is widely used in traditional communities in many different folk remedies and products derived from it are sold in public markets throughout northeastern Brazil and as its body fat has many different therapeutic indications as a folk remedy. The present work evaluates the antibacterial activity of the body fat from the snake Boa constrictor when employed either alone or in combination with antibiotics and discusses the ecological implications of the use of this traditional remedy. Oil (OBC was extracted from body fat located in the ventral region of B. constrictor using hexane as a solvent. The antibacterial activity of OBC was tested against standard as well as multi-resistant lines, either alone and in combination with antibiotics. OBC did not demonstrate any relevant antibacterial activity against standard or multidrug-resistant bacterial strains. OBC showed synergistic activity when combined with the aminoglycoside antibiotics. Our results indicate that the body fat of Boa constrictor does not possess bactericidal activity, from the clinical point of view, but when combined with an antibiotic, the fat demonstrated a significant synergistic activity.

  17. Potentiation of aminoglycoside antibiotic activity using the body fat from the snake Boa constrictor

    Directory of Open Access Journals (Sweden)

    Felipe S. Ferreira

    2011-06-01

    Full Text Available Boa constrictor is widely used in traditional communities in many different folk remedies and products derived from it are sold in public markets throughout northeastern Brazil and as its body fat has many different therapeutic indications as a folk remedy. The present work evaluates the antibacterial activity of the body fat from the snake Boa constrictor when employed either alone or in combination with antibiotics and discusses the ecological implications of the use of this traditional remedy. Oil (OBC was extracted from body fat located in the ventral region of B. constrictor using hexane as a solvent. The antibacterial activity of OBC was tested against standard as well as multi-resistant lines, either alone and in combination with antibiotics. OBC did not demonstrate any relevant antibacterial activity against standard or multidrug-resistant bacterial strains. OBC showed synergistic activity when combined with the aminoglycoside antibiotics. Our results indicate that the body fat of Boa constrictor does not possess bactericidal activity, from the clinical point of view, but when combined with an antibiotic, the fat demonstrated a significant synergistic activity.

  18. Porocephalus species (Pentastomida infecting Boa constrictor (Boidae and Lachesis muta (Viperidae in northeastern Brazil

    Directory of Open Access Journals (Sweden)

    Miriam Camargo Guarnieri

    2008-06-01

    Full Text Available Brazil has a great diversity of snakes, but there are few published works concerning parasitism in these animals. The present paper examined pulmonary infection by pentastomids in large snakes from northeastern Brazil, including six specimens of Boa constrictor and two examples of Lachesis muta from the Serpentarium of the Federal University of Pernambuco (UFPE, Brazil, all of which were collected in the Atlantic Coastal Forest. One specimen of B. constrictor was infected by Porocephalus sp. (intensity of infection 5.0 and one specimen of L. muta was infected by P. stilesi (intensity of infection 15.0.

  19. Morphological and molecular identification of ticks infesting Boa constrictor (Squamata, Boidae in Manaus (Central Brazilian Amazon

    Directory of Open Access Journals (Sweden)

    Leonardo Costa Fiorini

    2014-12-01

    Full Text Available The Boa constrictor is one of the world's largest vertebrate carnivores and is often found in urban areas in the city of Manaus, Brazil. The morphological identification of ticks collected from 27 snakes indicated the occurrence of Amblyomma dissimile Koch 1844 on all individuals sampled. In contrast, Amblyomma rotundatum Koch was found on only two snakes. An analysis of the 16S rRNA molecular marker confirmed the morphological identification of these ectoparasites.

  20. Diphtheroid colitis in a Boa constrictor infected with amphibian Entamoeba sp.

    Science.gov (United States)

    Richter, Barbara; Kübber-Heiss, Anna; Weissenböck, Herbert

    2008-05-06

    A female boa (Boa constrictor) from a zoological collection was submitted for necropsy after sudden death. Prominent pathological findings included a diphtheroid colitis, endoparasitism, focal pneumonia and inclusion bodies typical for inclusion body disease (IBD). In the colon entamoebae were identified, which differed in size and distribution from Entamoeba invadens. Gene sequence analysis of the 18S ribosomal RNA revealed 100% similarity with an Entamoeba species from the African bullfrog (Pyxicephalus adspersus), probably Entamoeba ranarum. The snake was possibly immunosuppressed, and the source of infection remains unclear. This is the first report of an infection with an amphibian Entamoeba species associated with colitis in a snake.

  1. Tyzzeria boae n. sp., (Apicomplexa: Eimeriidae, a New Coccidium from the Kidney of the snake Boa constrictor constrictor (Serpentes: Boidae

    Directory of Open Access Journals (Sweden)

    Ralph Lainson

    1994-12-01

    Full Text Available A new species of Tyzzeria is described from the kidney of the snake Boa constrictor constrictor Linnaeus, from the State of Pará, north Brazil. Oocysts from the coacal contents matured in eight days, at approximately 24°C. They measured 19.0 x 18.0 (15.0 x 15.0 - 22.5 x 21.5 µm, shape-index (length/width 1.0 (1.0 - 1.1. The oocyst wall is of an extremely delicate single, colourless layer, with no micropyle. Division of the oocyst contents into the 8 naked sporozoites leaves a bulky, spherical oocyst residuum averaging 15.5 x 14.8 (13.5 x 13.5 - 18.5 x 17.5 µm; the sporozoites measure an average of 11.0 x 1.8 (8.5 x 1.25 - 12.5 x 2.0 µm, and possess both anterior and posterior refractile bodies. Tyzzeria boae n.sp. is unique among the recorded species of the genus by virtue of its development in the epithelial cells of the distal convoluted tubules and collecting tubules of the kidney: stages in the merogony and gametogony of the parasite are described and figured.

  2. Porocephalus species (Pentastomida infecting Boa constrictor (Boidae and Lachesis muta (Viperidae in northeastern Brazil

    Directory of Open Access Journals (Sweden)

    Waltécio de Oliveira Almeida

    2008-01-01

    Full Text Available http://dx.doi.org/10.5007/2175-7925.2008v21n2p165 Espécies de Porocephalus (Pentastomida infectando Boa constrictor (Boidae e Lachesis muta (Viperidae na Região Nordeste do Brasil.  O Brasil possui uma grande diversidade de cobras, mas há poucos trabalhos realizados sobre parasitismo destas por pentastomídeos. No intuito de investigar o parasitismo pulmonar por pentastomídeos em grandes cobras na região nordeste, foram examinados seis espécimes de Boa constrictor e duas de Lachesis muta pertencentes à coleção do Serpentário da Universidade Federal de Pernambuco–UFPE, todos coletadas em localidades de mata úmida (Mata Atlântica. Apenas um espécime de B. constrictor estava infectado por Porocephalus sp. (intensidade de infecção 5,0. Apenas um espécime de L. muta estava infectado por P. stilesi (intensidade de infecção 15,0.

  3. Ultrasound and computed tomography description of the liver the Boa constrictor

    International Nuclear Information System (INIS)

    Zulim, Rosalia Marina Infiesta; Geller, Felipe Foletto; Souza, Priscila Macedo de; Mamprim, Maria Jaqueline; Rossetti, Diogo Pascoal; Comerlato, Alexandra Tiso

    2012-01-01

    Ultrasound is a method for noninvasive diagnosis, their effectiveness in the diagnosis of liver disease has been described in snakes. The liver is the largest organ of the coelomic cavity of reptiles. Elongated and flattened. The caudal vena cava and portal vein divides the body into two lobes. The hepatic parenchyma is homogeneous hypoechoic echogenicity. The objective is to describe and to obtain reference images in the study of liver four snakes of Boa constrictor amarali, through an ultrasound and tomography. Physical restraint made for the ultrasound examination held in prone position, to compare the texture and mark the structures for the slices on CT. A linear multifrequency probe of 6-10 mHz was used. The anesthetic protocol for computed tomography consisted of isoflurane. In helical CT scanner, the animal was positioned in the prone position, and used continuous cross sections of 2 mm by 2. The ultrasound and CT examinations allowed the identification of liver contours as well as the definition and extension of the caudal vena cava and portal vein. Normal pattern recognition of CT aspect of the present study will be of help in the diagnosis of liver diseases in snakes (Boa constrictor amarali). (author)

  4. An assessment of the impact of the pet trade on five CITES-Appendix II case studies - Boa constrictor imperator

    Science.gov (United States)

    Montgomery, Chad E.; Boback, Scott M.; Reed, Robert N.; Frazier, Julius A.

    2015-01-01

    Boa constrictor is a wide ranging snake species that is common in the pet trade and is currently listed in CITES Appendix II. Hog Island boas, or Cayos Cochinos boas, are a dwarf, insular race of Boa constrictor imperator endemic to the Cayos Cochinos Archipelago, Honduras. Cayos Cochinos boas are prized in the international pet trade for their light pink dorsal coloration, as well as for being much smaller and more docile than mainland boas (Porras, 1999; Russo, 2007). The boa population in the Cayos Cochinos was heavily exploited for the pet trade from 1979 to 1993, and researchers reported finding no boas on the islands during a five day herpetological survey trip in the early 1990s (Wilson and CruzDiaz, 1993), leading to the speculation that the population had been extirpated (e.g., Russo, 2007). The Cayos Cochinos Archipelago Natural Marine Monument has been managed by the Honduran Coral Reef Foundation since 1994 and prohibits removal of boas from the area. Poaching for the pet trade continues today, although at a lower level. Due to the endemic nature of this island morph of B. c. imperator it is imperative that we understand the dynamics of the populations and the ongoing threats that could negatively impact their long-term survival.

  5. Co-infecting Reptarenaviruses Can Be Vertically Transmitted in Boa Constrictor.

    Directory of Open Access Journals (Sweden)

    Saskia Keller

    2017-01-01

    Full Text Available Boid inclusion body disease (BIBD is an often fatal disease affecting mainly constrictor snakes. BIBD has been associated with infection, and more recently with coinfection, by various reptarenavirus species (family Arenaviridae. Thus far BIBD has only been reported in captive snakes, and neither the incubation period nor the route of transmission are known. Herein we provide strong evidence that co-infecting reptarenavirus species can be vertically transmitted in Boa constrictor. In total we examined five B. constrictor clutches with offspring ranging in age from embryos over perinatal abortions to juveniles. The mother and/or father of each clutch were initially diagnosed with BIBD and/or reptarenavirus infection by detection of the pathognomonic inclusion bodies (IB and/or reptarenaviral RNA. By applying next-generation sequencing and de novo sequence assembly we determined the "reptarenavirome" of each clutch, yielding several nearly complete L and S segments of multiple reptarenaviruses. We further confirmed vertical transmission of the co-infecting reptarenaviruses by species-specific RT-PCR from samples of parental animals and offspring. Curiously, not all offspring obtained the full parental "reptarenavirome". We extended our findings by an in vitro approach; cell cultures derived from embryonal samples rapidly developed IB and promoted replication of some or all parental viruses. In the tissues of embryos and perinatal abortions, viral antigen was sometimes detected, but IB were consistently seen only in the juvenile snakes from the age of 2 mo onwards. In addition to demonstrating vertical transmission of multiple species, our results also indicate that reptarenavirus infection induces BIBD over time in the offspring.

  6. Giant Constrictors: Biological and Management Profiles and an Establishment Risk Assessment for Nine Large Species of Pythons, Anacondas, and the Boa Constrictor

    Science.gov (United States)

    Reed, Robert N.; Rodda, Gordon H.

    2009-01-01

    Giant Constrictors: Biological and Management Profiles and an Establishment Risk Assessment for Nine Large Species of Pythons, Anacondas, and the Boa Constrictor, estimates the ecological risks associated with colonization of the United States by nine large constrictors. The nine include the world's four largest snake species (Green Anaconda, Eunectes murinus; Indian or Burmese Python, Python molurus; Northern African Python, Python sebae; and Reticulated Python, Broghammerus reticulatus), the Boa Constrictor (Boa constrictor), and four species that are ecologically or visually similar to one of the above (Southern African Python, Python natalensis; Yellow Anaconda, Eunectes notaeus; DeSchauensee's Anaconda, Eunectes deschauenseei; and Beni Anaconda, Eunectes beniensis). At present, the only probable pathway by which these species would become established in the United States is the pet trade. Although importation for the pet trade involves some risk that these animals could become established as exotic or invasive species, it does not guarantee such establishment. Federal regulators have the task of appraising the importation risks and balancing those risks against economic, social, and ecological benefits associated with the importation. The risk assessment quantifies only the ecological risks, recognizing that ecosystem processes are complex and only poorly understood. The risk assessment enumerates the types of economic impacts that may be experienced, but leaves quantification of economic costs to subsequent studies. Primary factors considered in judging the risk of establishment were: (1) history of establishment in other countries, (2) number of each species in commerce, (3) suitability of U.S. climates for each species, and (4) natural history traits, such as reproductive rate and dispersal ability, that influence the probability of establishment, spread, and impact. In addition, the risk assessment reviews all management tools for control of invasive giant

  7. Generation of Anti-Boa Immunoglobulin Antibodies for Serodiagnostic Applications, and Their Use to Detect Anti-Reptarenavirus Antibodies in Boa Constrictor.

    Directory of Open Access Journals (Sweden)

    Yegor Korzyukov

    Full Text Available Immunoglobulins (Igs, the key effectors of the adaptive immune system, mediate the specific recognition of foreign structures, i.e. antigens. In mammals, IgM production commonly precedes the production of IgG in the response to an infection. The reptilian counterpart of IgG is IgY, but the exact kinetics of the reptilian immune response are less well known. Boid inclusion body disease (BIBD, an often fatal disease of captive boas and pythons has been linked to reptarenavirus infection, and BIBD is believed to be immunosuppressive. However, so far, the study of the serological response towards reptarenaviruses in BIBD has been hampered by the lack of reagents. Thus we set up a purification protocol for boa constrictor IgY and IgM, which should also be applicable for other snake species. We used centrifugal filter units, poly ethylene glycol precipitation and gel permeation chromatography to purify and separate the IgM and IgY fractions from boa constrictor serum, which we further used to immunise rabbits. We affinity purified IgM and IgY specific reagents from the produced antiserum, and labelled the reagents with horseradish peroxidase. Finally, using the sera of snakes with known exposure to reptarenaviruses we demonstrated that the newly generated reagents can be utilised for serodiagnostic purposes, such as immunoblotting and immunofluorescent staining. To our knowledge, this is the first report to show reptarenavirus-specific antibodies in boa constrictors.

  8. What makes the heart of Boa constrictor (Squamata: Boidae beat faster?

    Directory of Open Access Journals (Sweden)

    João Fabrício Mota Rodrigues

    2015-02-01

    Full Text Available Body size is highly correlated with metabolism, which in turn influences physiological rates such as heart rate. In general, heart rate is negatively influenced by the size of animal's body, but there is insufficient data corroborating this pattern in snakes. This study evaluated how body size affects heart rate in captive Boa constrictor Linnaeus, 1758. We measured the heart rate of 30 snakes using digital palpation and evaluated how this rate is influenced by body mass and sex using Analysis of Covariance (ANCOVA. The heart rate of the snakes was 58.8 ± 6.7 bpm (beats per minute. Body size, estimated as log-transformed body mass, negatively influenced heart rate (F1,28 = 10.27, p = 0.003, slope = -0.00004, R2 = 0.27, but sex had no effect (F1,27 = 0.07, p = 0.80. In conclusion, this result corroborates the negative relationship between body size and heart rate for snakes and reinforces the influence of related metabolic characteristics, such as body size, on the physiological parameters of snakes.

  9. Data for giant constrictors - Biological management profiles and an establishment risk assessment for nine large species of pythons, anacondas, and the boa constrictor

    Science.gov (United States)

    Jarnevich, C.S.; Rodda, G.H.; Reed, R.N.

    2011-01-01

    Giant Constrictors' Climate Space The giant constrictors' climate space data set represents the information needed to recreate the climate space and climate matching analyses in Reed and Rodda (2009). A detailed methodology and results are included in that report. The data include locations for nine species of large constrictors including Python molurus, Broghammerus reticulatus, P. sebae, P. natalensis, Boa constrictor, Eunectes notaeus, E. deschauenseei, E. beniensis, and E. murinus. The locations are from published sources. Climate data are included for monthly precipitation and average monthly temperature along with the species locations. The individual spreadsheets of location data match the figures in the Reed and Rodda (2009) report, illustrating areas of the mainland United States that match the climate envelope of the native range. The precipitation and temperature data at each location were used to determine the climate space for each species. Graphs of climate space formed the basis for the algorithms in the data set, and more details can be found in Reed and Rodda (2009). These algorithms were used in ArcGIS to generate maps of areas in the United States that matched the climate space of locations of the snakes in their native range. We discovered a rounding error in ArcGIS in the implementation of the algorithms, which has been corrected here. Therefore the shapefiles are slightly different than those appearing in the risk assessment figures illustrating areas of the United States that match the climate envelope of the species in their native ranges. However, the suitable localities are not different at the scale of intended use for these maps, although there are more noticeable differences between areas classified as 'too cold' and 'too hot'.

  10. Hepatozoon cf. terzii (Sambon & Seligman, 1907 infection in the snake Boa constrictor constrictor from north Brazil: transmission to the mosquito Culex quinquefasciatus and the lizard Tropidurus torquatus

    Directory of Open Access Journals (Sweden)

    Paperna I.

    2004-06-01

    Full Text Available Specimens of Hepatozoon-infected Boa constrictor constrictor were obtained from localities in Pará State, north Brazil. Gametocytes in erythrocytes of the peripheral blood measured 10 x 2.5-16.2 x 3.7 µm. They were similar to those described as Haemogregarina terzii by Sambon & Seligmann (1907 in B. c. constrictor, in that they did not distort the infected erythrocyte, and their dimensions approximated those given by Carini (1947. Lungs and liver of infected snakes contained actively dividing meronts of a single type, and cysts containing two to six cystozoites were also present in the liver. Our initial feeding of Culex quinquefasciatus on infected snakes consistently resulted in a heavy death-rate of the engorged mosquitoes, with only a few surviving till the 9th day post feeding. These contained numerous oocysts which were undivided or in early stages of division. A fifth and final experiment, however, provided a few mosquitoes surviving up to 21 days post infection (dpi, and these contained fully sporulated oocysts measuring 190-200 µm in diameter and containing over 60 sporocysts of 19-30 µm in diameter. The number of sporozoites in each sporocyst was estimated as approximately 50. The nature of the parasite's sporogonic cycle in the mosquito thus justifies inclusion of this haemogregarine in the genus Hepatozoon. Two wild-caught specimens of the lizard Tropidurus torquatus were fed with mosquitoes containing fully developed oocysts (21 dpi. When sacrificed, three months later, large numbers of dizoic, tetrazoic and hexazoic cysts were demonstrated in their livers. Cystozoites released from these cysts were shown to possess a conspicuous refractile body.

  11. Seasonal influence on biochemical profile and serum protein electrophoresis for Boa constrictor amarali in captivity

    Directory of Open Access Journals (Sweden)

    LFN Silva

    Full Text Available Similarly to other reptiles, snakes are ectothermic animals and depend exclusively on the environment for the maintenance of their physiological, biochemical and immunological processes. Thus, changes in biochemical values can be expected due to seasonal influence. Twenty-two adult specimens of Boa constrictor amarali kept in captivity were used. Blood collections were done in two different seasons: winter (July 2004 and summer (January 2005 for the following assays: uric acid, aspartate aminotransferase (AST, glucose, cholesterol, total protein, and serum protein electrophoresis. The mean biochemical results found in summer and winter, respectively, were: 6.3 ± 3.4 and 11.3 ± 6.2 mg/dL for uric acid; 28.7 ± 12.4 and 20.7 ± 16.2 UI/L for AST; 26.3 ± 17 and 17.4 ± 6.8 mg/dL for glucose; 67.3 ± 30.2 and 69.7 ± 38.5 mg/dL for cholesterol; and 5.9 ± 1.6 and 5.9 ± 1.4 g/dL for total protein. Results regarding electrophoresis in summer and winter, respectively, were: 1.9 ± 0.7 and 2.4 ± 0.6 g/dL for albumin; 0.7 ± 0.2 and 0.5 ± 0.2 g/dL for α-globulin; 1.5 ± 0.5 and 1.7 ± 0.6 g/dL for β-globulin; and 1.8 ± 0.5 and 1.5 ± 0.5 g/dL for g-globulin. In the summer, there was a significant increase in AST and a decrease in uric acid (p < 0.05. Serum protein electrophoresis showed a significant increase in α-globulin fraction (p < 0.05 in the same season. There were not significant differences between seasons for the remaining variables. Based on these results, the period of the year must be considered in the interpretation of some biochemical values for these animals.

  12. Actividad de rastreo en Boa constrictor occidentalis (Serpentes: Boidae, un mecanismo de localización de la especie

    Directory of Open Access Journals (Sweden)

    Silmara Cervantes, Raquel

    1999-01-01

    Full Text Available En el presente trabajo se experimentó sobre la habilidad de Boa constrictor occidentalis para discriminar y seguir olores feromonales conespecíficos y heteroespecíficos. Las hembras presentaron elevada frecuencia de extrusiones de lengua hacia los estímulos de olor de piel de macho, piel de hembra y glándula de hembra, mostrando un mayor desplazamiento hacia el estímulo piel de hembra. Los machos respondieron con un incremento en el número de lengüeteos y búsqueda activa de los rastros frente a las secreciones de macho. Ambos sexos manifestaron preferencia por los olores conespecíficos aumentando la intensidad del lengüeteo y el seguimiento activo de rastros, mientras que exhibieron una marcada disminución de la frecuencia de extrusiones de lengua y escaso desplazamiento frente al estímulo heteroespecífico. Los resultados sugieren la estrecha relación existente entre la identificación de un estímulo mediante el lengüeteo y la actividad de rastreo. The ability in adult Boa constrictor occidentalis to discriminate between species and sexes and follow pheromonal trails was tested. Females presented elevated tongue flick rate (T.F.R. to male skin odor, female skin odor and female cloacal secretion. Trailing activity was higher to female skin odor. Males answered with elevated T.F.R. and exhibited active movements and searching of trails to their own secretions —male skin and male cloacal musk—. Both sexes had preferences to conespecific stimuli showing higher T.F.R. and active trailing while they were not interested in heterospecific trails presenting lower T.F.R. and limited movements. Results suggest the relationship between stimuli recognition by tongue flicking and trailing activity.

  13. HALLAZGO CASUAL DE UN PICHÓN DE Tiaris bicolor ( AV E S : THRAUPIDAE EN EL TRACTO DIGESTIVO DE UNA SERPIENTE Boa constrictor I CASUAL FINDING OF ONE CHICK OF Tiaris bicolor (AVES: THRAUPIDAE IN THE DIGESTIVE TRACT OF A Boa constrictor

    Directory of Open Access Journals (Sweden)

    Cristina Sainz-Borgo

    2018-05-01

    Full Text Available The Boa constrictor (Red-Tailed Boa is a specie that has a very diverse diet ranging from small prey such as birds, squirrels, fish and lizards to larger prey such as deer. The aim of this note was to report the casual finding of one chick of Tiaris bicolor (Black-faced Grassquit in the digestive tract of a B. constrictor that accidentally was seriously injured with a lawnmower, causing his death. One of their injuries exposed the T. bicolor chick eaten by the snake. The observation was made in a garden of a residential area located in southeast of Caracas city (Venezuela..

  14. Doença do corpúsculo de inclusão e espondilite por Salmonella sp. em uma Boa constrictor constrictor

    Directory of Open Access Journals (Sweden)

    Isabela Hardt

    Full Text Available RESUMO: Doença do corpúsculo de inclusão (IBD é uma enfermidade caracterizada por corpúsculos intracitoplasmáticos em diversos tecidos, principalmente no sistema nervoso central, responsável pelos principais sinais clínicos atribuídos à doença que acomete Boas e Phytons de cativeiro; essa enfermidade tem sido uma preocupação mundial devido à alta morbidade e mortalidade. O diagnóstico é feito pela visualização dos corpúsculos causados por um Arenavírus modificado. Salmonella sp. pertence à microflora de animais de sangue frio e quente, e é um patógeno oportunista que pode causar quadros gastrointestinais ou septicêmicos. Em répteis a Salmonella sp. é a bactéria com maior frequência de citações em espondilites e osteomielites. Relata-se um caso de uma jiboia (Boa constrictor constrictor que apresentava restrição de movimento e múltiplos granulomas dorsais nas vértebras; à radiografia evidenciaram-se regiões fraturadas. Após meses de tratamentos sem melhora clínica e o aparecimento de novas lesões o animal ficou prostrado, anoréxico, caquético e desenvolveu opistótono; optou-se pela eutanásia. À necropsia verificaram-se, nas vértebras, múltiplos focos dorsais com aumento de volume que variava de 1,7cm à 3,8cm. Ao corte as vértebras eram deformadas e exibiam conteúdo caseoso focal próximo ao canal medular, este foi coletado para microbiologia onde se identificou Salmonella sp. À microscopia as vértebras tinham um infiltrado inflamatório multifocal moderado de macrófagos e heterofilos. Algumas áreas possuíam grande quantidade de granulomas com calcificação central e inúmeras células gigantes; outros mostravam áreas de osteomalácia e fibrose. Em raros focos havia fratura do corpo vertebral e compressão da medula espinhal com leve infiltrado inflamatório invadindo o canal medular. No pulmão, principalmente no epitélio brônquico, por vezes até dentro de linfócitos do tecido linfoide

  15. Ultra-sonografia do fígado, aparelho renal e reprodutivo da jibóia (Boa constrictor Ultrasonography of the liver, renal and reproductive apparatus of Boa constrictor Snake

    Directory of Open Access Journals (Sweden)

    Francisco C. P. Neto

    2009-04-01

    Full Text Available Atualmente os animais silvestres têm despertado o interesse particular na criação domestica. Na medicina de animais selvagens, os exames ultra-sonográficos podem ser considerados como ferramenta para diagnosticar e prevenir doenças. Deste modo, realizou-se um estudo em 20 jibóias (Boa constrictor, a fim de caracterizar a morfologia e aparência ultra-sonográfica das estruturas presentes da cavidade celomática desses animais. Ultra-sonograficamente, o fígado apresentou-se variando de hipoecóica a levemente hiperecogênica, com margens ecogênicas e ecotextura homogênea em toda sua extensão. Os rins mostraram formato elipsóide, com cápsula fina, regular e hiperecóica. Os folículos ovarianos apresentaram formato ovóide, margens finas, regulares e discretamente hiperecóicas. As estruturas do sistema reprodutor do macho não foram evidenciadas com precisão, devido a sua ecogenicidade similar em relação às estruturas adjacentes e pela presença do "corpo gorduroso" localizado nessa região. A ultra-sonografia da cavidade celomática em jibóias demonstrou ser uma técnica rápida e de fácil acesso, permitindo identificar a morfologia, sintopia e aparência ultra-sonográfica de estruturas como o fígado, rins e de folículos vitelogênicos nas fêmeas.Currently, wild animals have been received special attention for domestic breeding. In Wild Animal Medicine, ultrasonographic exams could be considered as a tool to diagnose and prevent disease. Ultrasonographic examination of twenty snakes (Boa constrictor was performed in order to describe the morphological and ultrasonography appearance of their coelomic structures. Examination by ultrasonography revealed the parechymal liver ranging from slightly hypoechogenic to hyperechogenic, with echogenic margins and homogeneous echotexture in total scanning of this organ. The kidney was accessible for examination by sagittal ultrasound, showing an ellipsoid shape, a hyperechogenic capsule

  16. Variação sazonal dos valores de bioquímica sérica de jiboias amazônicas (Boa constrictor constrictor mantidas em cativeiro

    Directory of Open Access Journals (Sweden)

    Dennis José da Silva Lima

    2012-09-01

    Full Text Available http://dx.doi.org/10.5007/2175-7925.2012v25n4p165   Na região Norte do Brasil, as estações do ano não são bem definidas como acontece nas regiões Sul e Sudeste, devido ao clima equatorial quente e úmido, com um período mais chuvoso, conhecido como inverno amazônico, e um período menos chuvoso, conhecido como verão amazônico. Com esta pesquisa, objetivou-se avaliar a variação dos valores bioquímicos séricos de jiboias amazônicas correlacionadas com a sazonalidade da região. Foram realizadas análises bioquímicas séricas (AST, ALT, DHL, FA, cálcio, ácido úrico, fósforo, proteína total, albumina e globulina de 31 serpentes da espécie Boa constrictor constrictor, mantidas em cativeiro. Levando em consideração a variável sazonalidade, observou-se que oito dos dez parâmetros são maiores no inverno em comparação ao verão (proteína total, albumina, globulina, ALT, AST, FA, DHL e cálcio sendo que os valores de ALT, AST e cálcio mostraram ter diferenças estatísticas significantes no verão e inverno amazônicos, enquanto que os demais parâmetros parecem não ser influenciados pela sazonalidade. Esta foi a primeira pesquisa, em cativeiro, analisando o perfil bioquímico sérico serpentes Boa constrictor constrictor no Estado do Pará.

  17. Identification, characterization, and in vitro culture of highly divergent arenaviruses from boa constrictors and annulated tree boas: candidate etiological agents for snake inclusion body disease.

    Science.gov (United States)

    Stenglein, Mark D; Sanders, Chris; Kistler, Amy L; Ruby, J Graham; Franco, Jessica Y; Reavill, Drury R; Dunker, Freeland; Derisi, Joseph L

    2012-01-01

    Inclusion body disease (IBD) is an infectious fatal disease of snakes typified by behavioral abnormalities, wasting, and secondary infections. At a histopathological level, the disease is identified by the presence of large eosinophilic cytoplasmic inclusions in multiple tissues. To date, no virus or other pathogen has been definitively characterized or associated with the disease. Using a metagenomic approach to search for candidate etiologic agents in snakes with confirmed IBD, we identified and de novo assembled the complete genomic sequences of two viruses related to arenaviruses, and a third arenavirus-like sequence was discovered by screening an additional set of samples. A continuous boa constrictor cell line was established and used to propagate and isolate one of the viruses in culture. Viral nucleoprotein was localized and concentrated within large cytoplasmic inclusions in infected cells in culture and tissues from diseased snakes. In total, viral RNA was detected in 6/8 confirmed IBD cases and 0/18 controls. These viruses have a typical arenavirus genome organization but are highly divergent, belonging to a lineage separate from that of the Old and New World arenaviruses. Furthermore, these viruses encode envelope glycoproteins that are more similar to those of filoviruses than to those of other arenaviruses. These findings implicate these viruses as candidate etiologic agents of IBD. The presence of arenaviruses outside mammals reveals that these viruses infect an unexpectedly broad range of species and represent a new reservoir of potential human pathogens. Inclusion body disease (IBD) is a common infectious disease of captive snakes. IBD is fatal and can cause the loss of entire animal collections. The cause of the disease has remained elusive, and no treatment exists. In addition to being important to pet owners, veterinarians, breeders, zoological parks, and aquariums, the study of animal disease is significant since animals are the source of

  18. Detection and prevalence of boid inclusion body disease in collections of boas and pythons using immunological assays.

    Science.gov (United States)

    Chang, L; Fu, D; Stenglein, M D; Hernandez, J A; DeRisi, J L; Jacobson, E R

    2016-12-01

    Inclusion body disease (IBD) of boas and pythons is characterized by the intracytoplasmic accumulation of an antigenic 68 kDa viral protein IBDP, more recently known as the nucleoprotein (NP) of the reptarenaviruses. Blood samples of 131 captive boas and pythons (53 boa constrictors, Boa constrictor; 35 rainbow boas, Epicrates cenchria; 22 ball pythons, Python regius; 5 carpet pythons, Morelia spilota; 6 Burmese pythons, Python bivittatus; 4 Jamaican boas, Epicrates subflavus; 5 anacondas, Eunectes spp.; and 1 green tree python, Morelia viridis) were obtained from 28 collections in the USA. Diagnosis of IBD was initially made by the identification of eosinophilic intracytoplasmic inclusion bodies in hematoxylin and eosin (HE) stained blood films and isolated peripheral white blood cells (PWBC). The overall prevalence of IBD in study snakes was 25/131 or 19% (95% CI = 12.4%, 25.8%) with boa constrictors being more commonly infected (22/53 or 41.5%; 95% CI = 28.2%, 54.8%) than other species in this study. Of the 22 IBD positive boa constrictors, 87% were clinically healthy, 13% had various signs of chronic illness, and none showed signs of central nervous system disease. Using a validated monoclonal anti-NP antibody, NP was confirmed within the isolated PWBC by immunohistochemical staining and Western blots. The presence of reptarenaviruses within blood samples of 27 boa constrictors and three rainbow boas was also assessed by PCR. Among boa constrictors, very good agreements were shown between the observation of inclusion bodies (by HE stain) and the presence of NP (by immunohistochemistry, kappa = 0.92; and Western blots, kappa = 0.89), or the presence of reptarenaviruses (by PCR; kappa = 0.92). Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Fatal attack on black-tufted-ear marmosets (Callithrix penicillata) by a Boa constrictor: a simultaneous assault on two juvenile monkeys.

    Science.gov (United States)

    Teixeira, Danilo Simonini; dos Santos, Edmilson; Leal, Silvana Gomes; de Jesus, Andrea Karla; Vargas, Waldemir Paixão; Dutra, Irapuan; Barros, Marilia

    2016-01-01

    Here we report the first witnessed attack on a marmoset by a constrictor snake. The incident occurred mid-morning in a gallery forest within an altered landscape of the Cerrado region of central Brazil and refers to a fatal attack by a Boa constrictor on two juvenile black-tufted-ear marmosets (Callithrix penicillata) simultaneously. The snake captured both individuals at a height of ~ 4 m while a group of eight marmosets traveled through the subcanopy. The actual strike was not seen. After 2 min, the boa fell to the ground with both marmosets in its coils and proceeded to kill one animal at a time through constriction. Two adult marmosets immediately descended to where the snake held its victims on the ground and attacked it. The snake showed no apparent reaction, and after ~ 1-2 min, the adults rejoined the remaining group members that were mobbing and vocalizing from 5 to 6 m above. The group left the scene ~ 7 min after the onset of the attack and was not seen again. The snake loosened its coils 10 min after its initial strike, left the two carcasses on the ground and stayed behind a nearby tree. Thus, we are not sure if the victims were in fact ingested. This report confirms that marmosets are vulnerable to boid snakes and capable of highly organized and cooperative antipredation behavior. It also suggests that snakes pose a greater threat to callitrichids than previously thought.

  20. Uso del hábitat por Boa constrictor occidentalis (Serpentes: Boidae durante la estación seca en Córdoba, Argentina

    Directory of Open Access Journals (Sweden)

    Attademo, Andrés

    2004-07-01

    Full Text Available El análisis sobre el uso del hábitat es una herramienta fundamental para la conservación y el manejo de las poblaciones silvestres. Cuantificar los cambios en el uso de recursos asociados con la reproducción puede ofrecer una idea de las fuerzas selectivas que actúan sobre los organismos durante esta fase crítica de su historia de vida. Se ha observado en distintas especies de ofidios que hembras grávidas frecuentan hábitats distintos de los que utilizan hembras no grávidas y machos, por lo que la selección de un ambiente en particular podría estar influenciado por el comportamiento reproductivo. En el presente trabajo evaluamos el uso del hábitat en Boa constrictor occidentalis mediante radiorastreo a nivel de microhábitat durante la estación seca en la localidad de El Quemado, Departamento Pocho, Córdoba. Se marcaron mediante radiotransmisores 14 individuos adultos: 5 hembras reproductivas, 4 hembras no reproductivas y 5 machos reproductivos. Las diferencias en el uso del hábitat observadas en las lampalaguas en función de la condición reproductiva durante la estación seca, reflejarían diferencias en los requerimientos para la termorregulación. El uso que las hembras reproductivas hacen del hábitat les permitiría seleccionar sitios que brinden buenos lugares para asolearse permitiendo obtener temperaturas mayores y óptimas para el desarrollo de los embriones. Habitat use analysis is a basic tool for the conservation and management of wild populations. Quantifying the changes in the use of resources associated with reproduction can offer an insight into the selective forces acting on organisms in this critical phase of life history. Reproduction condition often has obvious effects on habitat use. Reproductive individual females have been observed in habitats different from those frequented by males and non reproductive females. In this study, we evaluate the differential use of habitats in Boa constrictor occidentalis

  1. Detection of nidoviruses in live pythons and boas.

    Science.gov (United States)

    Marschang, Rachel E; Kolesnik, Ekaterina

    2017-02-09

    Nidoviruses have recently been described as a putative cause of severe respiratory disease in pythons in the USA and Europe. The objective of this study was to establish the use of a conventional PCR for the detection of nidoviruses in samples from live animals and to extend the list of susceptible species. A PCR targeting a portion of ORF1a of python nidoviruses was used to detect nidoviruses in diagnostic samples from live boas and pythons. A total of 95 pythons, 84 boas and 22 snakes of unknown species were included in the study. Samples tested included oral swabs and whole blood. Nidoviruses were detected in 27.4% of the pythons and 2.4% of the boas tested. They were most commonly detected in ball pythons (Python [P.] regius) and Indian rock pythons (P. molurus), but were also detected for the first time in other python species, including Morelia spp. and Boa constrictor. Oral swabs were most commonly tested positive. The PCR described here can be used for the detection of nidoviruses in oral swabs from live snakes. These viruses appear to be relatively common among snakes in captivity in Europe and screening for these viruses should be considered in the clinical work-up. Nidoviruses are believed to be an important cause of respiratory disease in pythons, but can also infect boas. Detection of these viruses in live animals is now possible and can be of interest both in diseased animals as well as in quarantine situations.

  2. Uso de cetamina pela via cólon-retal para contenção química de jiboias Boa constrictor Linnaeus, 1758 com teste de influência da droga sobre o sistema renal

    Directory of Open Access Journals (Sweden)

    Tatiale O. Rodrigues

    Full Text Available RESUMO: Por serem frequentes na clínica de animais silvestres, faz-se necessária a manipulação de jiboias e para isso, indispensável o conhecimento sobre as manobras precisas para o tratamento das possíveis afecções. Quando se opta pela contenção química, ou pela realização de procedimentos cirúrgicos, um dos fármacos utilizados na anestesia de serpentes é a cetamina. Viu-se a necessidade de buscar uma via alternativa, semelhante em eficácia às tradicionais para a contenção química, porém que minimizasse os riscos e efeitos adversos encontrados na sua execução. O presente trabalho sugere que a via retal seja esta alternativa, por isso, treze jiboias foram submetidas à administração de 70mg/kg de cloridrato de cetamina, com sonda uretral, através da cloaca até o cólon-reto. Foram avaliados, nos tempos 0, 10, 20, 30, 40, 50, 60, 70, 80, 90 e 120 minutos, a partir da administração do fármaco, os seguintes parâmetros: frequência cardíaca, relaxamento muscular e mobilidade, resistência à contenção ou manipulação e reação postural de endireitamento. Foi realizada coleta de 0,5mL de sangue por punção do seio venoso paravertebral cervical, antes da administração do fármaco, no dia seguinte e após nove dias. Foram dosadas as concentrações plasmáticas de cálcio, fósforo e ácido úrico de todos os exemplares a fim de verificar o perfil bioquímico renal e avaliar a influência do fármaco neste sistema. Não foram observadas alterações bioquímicas plasmáticas durante o período de avaliação. Foi possível promover a contenção química das jiboias Boa constrictor, utilizando cloridrato de cetamina pela via cólon-retal.

  3. Osteossíntese mandibular em jiboia (Boa constrictor)

    OpenAIRE

    Castro, Jorge Luiz Costa; Pontíficia Universidade Católica do Paraná; Santalucia, Sérgio; Universidade Federal de Santa Maria; Pachaly, José Ricardo; Universidade Paranaense; Villanova Junior, José Ademar; Pontífica Universidade Católica do Paraná; Castro, Verônica Souza Paiva; Universidade Federal de Santa Maria; Balthazar, Daniel Almeida; Fundação RIOZOO - RJ.; Spadetti, Alex Lucas; Fundação Parque Jardim Zoológico; Souza, Wilker Nazareth; Universidade Castelo Branco; Fedullo, Luiz Paulo Luzes; Fundação RIOZOO - RJ; Raiser, Alceu Gaspar; Universidade Federal de Santa Maria

    2014-01-01

    Nowadays are observed an increase in the finding of certain wild animals in urban areas, due to environmental changes caused by deforestation and economic use of natural areas. It causes disappearance of usual prey and forces these animals, including snakes, to migrate to urban areas, becoming vulnerable to injuries caused by aggressions, car accidents and capture. Mandibular and maxillar fractures are common in many animal species, representing about 3-6% of all bone fractures in dogs and ca...

  4. Determinação de hemogregarina em Boa constrictor constrictor mantidos em cativeiro

    Directory of Open Access Journals (Sweden)

    Monique A. Luz

    2012-08-01

    Full Text Available O presente estudo teve como objetivo determinar a presença de hemogregarina em boídeos mantidos em cativeiro no Estado do Pará, bem como, relacionar a hemoparasitose com pre-disposição sexual, alterações clínicas e hematológicas e a presença de ectoparasitos. Esta pesquisa teve autorização do Sistema de Autorização e Informação em Biodiversidade do Instituto Brasileiro do Meio Ambiente e dos Recursos Naturais Renováveis para ser realizado. Utilizaram-se 19 serpentes da família Boidae mantidas em cativeiro, pertencentes ao "Museu Paraense Emilio Goeldi" (Belém/PA e "Sítio Xerimbabo" (Santo Antônio do Tauá/PA. A pesquisa de hemogregarina foi realizada em esfregaços sanguíneos examinados no aumento de 400x, enquanto que a parasitemia foi determinada contando- se 550 hemácias em aumento de 1000x. Do total de animais estudados (n=19, nove encontraram-se parasitados (47,36%, não havendo correlação entre presença de hemogregarina, pré-disposição sexual, alterações clínicas e hematológicas nas serpentes hospedeiras. A correlação da hemoparasitose foi detectada apenas quanto à presença de ectoparasitas nas serpentes, no entanto, estudos adicionais são necessários para verificar a prevalência de hemogregarinas em animais mantidos em cativeiro no Estado do Pará, visto que, existe grande lacuna de dados na literatura veterinária especializada no que diz respeito à fauna da região amazônica.

  5. The Correspondence between Descartes and Henricus Regius

    NARCIS (Netherlands)

    Bos, J.J.F.M.

    2002-01-01

    In 1638 the Dutch philosopher and physician Henricus Regius (1598 1679) introduced himself to René Descartes (1596 1650), allegedly because he owed his appointment as professor of theoretical medicine at Utrecht University to his being a Cartesian. During the following years Regius established

  6. Boa leitura!

    Directory of Open Access Journals (Sweden)

    Ana Lúcia Enne

    2011-01-01

    , propõe uma detalhada metodologia para delimitação do corpus em pesquisas de semiótica.


    Desejamos a todos uma boa leitura e aproveitamos para lembrar que as chamadas para nossas próximas edições continuam abertas.

     

  7. Bente Boa, Torm, Denmark

    DEFF Research Database (Denmark)

    Wagtmann, Maria Anne

    2009-01-01

    At the beginning of July 2009, Maria Anne Wagtmann (Associate Professor, PhD, University of Southern Denmark) had the opportunity to interview Ms Bente Boa, a senior marine HR manager in the Danish ship owning firm TORM A/S' (http://www.torm.com/). Bente Boa is also chairwoman of the "The Sea...

  8. Molecular Identification of Cryptosporidium Species from Pet Snakes in Thailand

    OpenAIRE

    Yimming, Benjarat; Pattanatanang, Khampee; Sanyathitiseree, Pornchai; Inpankaew, Tawin; Kamyingkird, Ketsarin; Pinyopanuwat, Nongnuch; Chimnoi, Wissanuwat; Phasuk, Jumnongjit

    2016-01-01

    Cryptosporidium is an important pathogen causing gastrointestinal disease in snakes and is distributed worldwide. The main objectives of this study were to detect and identify Cryptosporidium species in captive snakes from exotic pet shops and snake farms in Thailand. In total, 165 fecal samples were examined from 8 snake species, boa constrictor (Boa constrictor constrictor), corn snake (Elaphe guttata), ball python (Python regius), milk snake (Lampropeltis triangulum), king snake (Lampropel...

  9. 75 FR 11808 - Injurious Wildlife Species; Listing the Boa Constrictor, Four Python Species, and Four Anaconda...

    Science.gov (United States)

    2010-03-12

    ..., pond and stream, and swamp habitats, including extensive use of Nigerian mangrove habitats. In the arid... Paraguay Rivers in Brazil; and extending south as far as the Tropic of Capricorn in northeast Paraguay. The... is the Itenez/Guapore River in Bolivia along the border with Brazil, as well as the Baures River...

  10. 75 FR 38069 - Injurious Wildlife Species; Listing the Boa Constrictor, Four Python Species, and Four Anaconda...

    Science.gov (United States)

    2010-07-01

    ... Python Species, and Four Anaconda Species as Injurious Reptiles AGENCY: Fish and Wildlife Service... regulations to add Indian python (Python molurus, including Burmese python Python molurus bivittatus), reticulated python (Broghammerus reticulatus or Python reticulatus), Northern African python (Python sebae...

  11. Strike kinematics and performance in juvenile ball pythons (Python regius).

    Science.gov (United States)

    Ryerson, William G; Tan, Weimin

    2017-08-01

    The rapid strike of snakes has interested researchers for decades. Although most work has focused on the strike performance of vipers, recent work has shown that other snakes outside of the Viperidae can strike with the same velocities and accelerations. However, to date all of these examples focus on performance in adult snakes. Here, we use high-speed video to measure the strike kinematics and performance of 10 juvenile (pythons, Python regius. We find that juvenile P. regius strike at levels comparable to larger snakes, but with shorter durations and over shorter distances. We conclude that the juvenile P. regius maintain performance likely through manipulation of the axial musculature and accompanying elastic tissues, and that this is a first step to understanding ontogenetic changes in behavior and a potential avenue for understanding how captivity may also impact behavior. © 2017 Wiley Periodicals, Inc.

  12. Reproductive biology of spiny lobster Panulirus regius from the ...

    African Journals Online (AJOL)

    Reproductive biology of spiny lobster Panulirus regius from the northwestern Cape Verde Islands. R Freitas, A Medina, S Correira, M Castro. Abstract. No Abstract. African Journal of Marine Science Vol.29(2) 2007: pp. 201-208. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL ...

  13. The spectacle of the ball python (Python regius)

    DEFF Research Database (Denmark)

    Da Silva, Mari-Ann Otkjær; Heegaard, Steffen; Wang, Tobias

    2014-01-01

    A detailed morphological description of the spectacle of the ball python (Python regius) is provided. The eyes of 21 snakes were examined by light microscopy and/or transmission electron microscopy. Additionally, eyes of nine live snakes were examined using optical coherence tomography (OCT...

  14. [Remembering Ismar Boas (1858 - 1938)].

    Science.gov (United States)

    Hansen, W E

    2013-04-01

    Ismar Boas is revered as one of the pioneers of modern gastroenterology. 75 years after his suicide due to Nazism it is appropriate to remember the great clinician and scientist. Moreover in a newly detected report from his hands some information on his thinking and handling of medical problems can be derived and his view of medial progress until today can be assessed. © Georg Thieme Verlag KG Stuttgart · New York.

  15. Oral flora of Python regius kept as pets.

    Science.gov (United States)

    Dipineto, L; Russo, T P; Calabria, M; De Rosa, L; Capasso, M; Menna, L F; Borrelli, L; Fioretti, A

    2014-05-01

    This study was aimed at evaluating the oral bacterial flora of 60 Python regius kept as pets by culture and biochemical methods. All isolates were also submitted to antimicrobial susceptibility testing using the disc diffusion method. The oral cavity of snakes sampled harboured a wide range of Gram-negative bacteria mainly constituted by Pseudomonas spp., Morganella morganii, Acinetobacter calcoaceticus, Aeromonas hydrophila, but also by Salmonella spp. Staphylococcus spp. was the commonest Gram-positive isolates, and various anaerobic Clostridium species were also found. The most effective antimicrobial agents were enrofloxacin and ciprofloxacin, followed by doxycycline and gentamicin. The oral cavity of snakes sampled harboured a wide range of bacteria. Our results suggest that people who come in contact with snakes could be at risk of infection and should follow proper hygiene practices when handling these reptiles. © 2014 The Society for Applied Microbiology.

  16. Infestation of Royal Python (Python regius) with ticks Amblyomma ...

    African Journals Online (AJOL)

    The Python/Boa Family is found in most part of tropics. It is a highly domesticated pet and can easily be handled (Cansdale 1962). Snakes are commonly infected by ticks more importantly the hand bodied ticks (Fowler, 1986).However, under captive condition, ticks usually exert a lot of burden on their hosts being carriers of ...

  17. Recent development of BOA version 3

    International Nuclear Information System (INIS)

    Deshon, J.; Hussey, D.; Westacott, J.; Young, M.; Secker, J.; Epperson, K.; McGurk, J.; Henshaw, J.

    2010-01-01

    BOA is the EPRI code developed to help understand material transport issues in PWR systems. In particular, BOA was developed to investigate the problem of crud induced power shifts (CIPS) or axial offset anomalies (AOA) that are related to crud accumulation on fuel clad and the subsequent uptake of boron within this crud. Over the last few years significant developments of BOA have taken place; these include new models for release and deposition of soluble and particulate material as well as new models for boron capture in the crud. The new version of BOA (version 3), as well as predicting the extent of AOA a plant might expect during a cycle, also predicts soluble and particulate Ni/Fe levels in the coolant, end of cycle Ni shut-down releases and the relative amounts of Ni/Fe within the fuel crud. The model is being validated against plant data and this paper briefly discusses the recent developments, the fundamental scientific basis for these changes and some of the validation studies. (author)

  18. Development of hemipenes in the ball python snake Python regius.

    Science.gov (United States)

    Leal, Francisca; Cohn, Martin J

    2015-01-01

    Within amniotes, external copulatory organs have undergone extensive morphological diversification. One of the most extreme examples is squamate (lizards and snakes) hemipenes, which are paired copulatory organs that extend from the lateral margins of the cloaca. Here, we describe the development of hemipenes in a basal snake, the ball python (Python regius). Snake hemipenes arise as a pair of lateral swellings on either side of the caudal part of the cloaca, and these paired outgrowths persist to form the left and right hemipenes. In non-squamate amniotes, external genitalia form from paired swellings that arise on the anterior side of the cloaca, which then fuse medially to form a single genital tubercle, the anlagen of the penis or clitoris. Whereas in non-squamate amniotes, Sonic hedgehog (Shh)-expressing cells of the cloacal endoderm form the urethral or sulcus epithelium and are required for phallus outgrowth, the hemipenes of squamates lack an endodermal contribution, and the sulcus does not express Shh. Thus, snake hemipenes differ from the genital tubercles of non-squamate amniotes both in their embryonic origins and in at least part of patterning mechanisms, which raises the possibility that hemipenes may not be direct homologs of the unpaired amniote penis. Nonetheless, we find that some developmental genes show similar expression patterns in snake hemipenes buds and non-squamate genital tubercles, suggesting that homologous developmental mechanisms are involved in aspects of external genital development across amniotes, even when these structures may have different developmental origins and may have arisen independently during evolution.

  19. BOA: Pipe asbestos insulation removal robot system

    International Nuclear Information System (INIS)

    Schempf, H.; Bares, J.; Schnorr, W.

    1995-01-01

    The BOA system is a mobile pipe-external robotic crawler used to remotely strip and bag asbestos-containing lagging and insulation materials (ACLIM) from various diameter pipes in (primarily) industrial installations. Steam and process lines within the DOE weapons complex warrant the use of a remote device due to the high labor costs and high level of radioactive contamination, making manual removal extremely costly and highly inefficient. Currently targeted facilities for demonstration and remediation are Fernald in Ohio and Oak Ridge in Tennessee

  20. The zoonotic implications of pentastomiasis in the royal python (python regius).

    Science.gov (United States)

    Ayinmode, Ab; Adedokun, Ao; Aina, A; Taiwo, V

    2010-09-01

    Pentastomes are worm-like endoparasites of the phylum Pentastomida found principally in the respiratory tract of reptiles, birds, and mammals. They cause a zoonotic disease known as pentastomiasis in humans and other mammals. The autopsy of a Nigerian royal python (Python regius) revealed two yellowish-white parasites in the lungs, tissue necrosis and inflammatory lesions. The parasite was confirmed to be Armillifer spp (Pentastomid); this is the first recorded case of pentastomiasis in the royal python (Python regius) in Nigeria. This report may be an alert of the possibility of on-going zoonotic transmission of pentastomiasis from snake to man, especially in the sub-urban/rural areas of Nigeria and other West African countries where people consume snake meat.

  1. The mechanical properties of the systemic and pulmonary arteries of Python regius correlate with blood pressures.

    Science.gov (United States)

    van Soldt, Benjamin J; Danielsen, Carl Christian; Wang, Tobias

    2015-12-01

    Pythons are unique amongst snakes in having different pressures in the aortas and pulmonary arteries because of intraventricular pressure separation. In this study, we investigate whether this correlates with different blood vessel strength in the ball python Python regius. We excised segments from the left, right, and dorsal aortas, and from the two pulmonary arteries. These were subjected to tensile testing. We show that the aortic vessel wall is significantly stronger than the pulmonary artery wall in P. regius. Gross morphological characteristics (vessel wall thickness and correlated absolute amount of collagen content) are likely the most influential factors. Collagen fiber thickness and orientation are likely to have an effect, though the effect of collagen fiber type and cross-links between fibers will need further study. © 2015 Wiley Periodicals, Inc.

  2. The Zoonotic Implications of Pentastomiasis in the Royal Python (Python Regius)

    OpenAIRE

    Ayinmode, AB; Adedokun, AO; Aina, A; Taiwo, V

    2010-01-01

    Pentastomes are worm-like endoparasites of the phylum Pentastomida found principally in the respiratory tract of reptiles, birds, and mammals. They cause a zoonotic disease known as pentastomiasis in humans and other mammals. The autopsy of a Nigerian royal python (Python regius) revealed two yellowish-white parasites in the lungs, tissue necrosis and inflammatory lesions. The parasite was confirmed to be Armillifer spp (Pentastomid); this is the first recorded case of pentastomiasis in the r...

  3. Image quality of a Konica Regius 336 digital system in chest radiography

    International Nuclear Information System (INIS)

    Ostinelli, A.; Frigerio, M.; Monti, A.F.; Gelosa, S.; Tognoli, P.; Perniola, N.; Gozzi, G.

    2000-01-01

    Digital radiographic systems permit to optimize execution, depiction and storage of radiological images. Since a Regius 336 digital system (Konica Corp. Tokyo, Japan) devoted to chest radiography Department of S. Anna Hospital in Como, Italy, it was investigated its performance relative to image quality. Konica Regius 336 is a computed radiography system made of a phosphorescence detector plate which is scanned with an infrared semiconductor laser beam. The radiographic image obtained from the detector is subjected to image processing, which allows a stable output and the nonlinear curve typical of conventional radiographic systems. Image quality was assessed based on the following parameters: dose, contrast, noise and spatial resolution. As reference, it was assessed the same parameters on a Cronex 88 analogic chest-changer (DuPont Pharma, North Billerica, Mass, USA). The Regius 336 air kerma values were always higher than the analogic ones (about 10%), both with and without a chest phantom; noise was also greater than in analogic images, sometimes even doubled. The optical densities of a step wedge and the spatial resolution of the digital chest-changer are independent of the X-ray tube voltage consequent to broader optical latitude. Inversely, the analogic images of the wedges show great optical density variability as a function of the X-ray tube voltage (in a range of 2). The modulation transfer functions of the two systems have the same trend. The performance of the Konica Regius 336 is nearly equivalent to that of an analogic system. The main advantages of the digital system are a standard output, lower consumption of radiographic films, higher productiveness and better image quality standard level [it

  4. Yearly growth and metabolic changes in earthen pond-cultured meagre Argyrosomus regius

    Directory of Open Access Journals (Sweden)

    Luis Vargas-Chacoff

    2014-06-01

    Full Text Available Metabolic modifications associated with natural environmental conditions were assessed in the meagre Argyrosomus regius cultured in earthen ponds under natural photoperiod and temperature. Juvenile specimens (90-100 g initial weight were sampled (plasma, liver and muscle every two months for 18 months (between December 2004 and May 2006. Specimens showed seasonal variations in growth rate, with the highest values in spring and summer. Plasmatic, hepatic and muscular metabolite levels and hepatic and muscular metabolic enzymes also showed significant variations throughout the year. Enzymatic activity related to carbohydrate metabolism in the liver (HK, FBPase and G6PDH showed great modifications in summer, increasing glycogenogenic pathways, while amino acid metabolism (GDH and GOT activity was enhanced in spring and summer. However lipid-related (G3PDH activity metabolic enzymes did not show a clear seasonal pattern. In muscle, enzymatic activity related to amino acid, lipid and lactate metabolism (LDH-O activity, but not carbohydrate metabolism, showed seasonal changes in parallel with changes in growth rate. Thus A. regius specimens showed a trend to grow in summer months and mobilize their energy reserves in winter. Differences in the hepatic level were observed between the first and the second year of the study, suggesting the possible existence of metabolic changes related to specimen age or size. Our results indicate that growth and metabolic responses in A. regius are environmentally dependent and that this species is a very good candidate for diversification in aquaculture.

  5. Bons video games e boa aprendizagem

    OpenAIRE

    James Paul Gee

    2009-01-01

    http://dx.doi.org/10.5007/2175-795X.2009v27n1p167   O artigo defende que os bons  videogames  incorporam bons princípios de aprendizagem, apoiados pelas  pesquisas  atuais  em Ciência Cognitiva, e os lista:  identidade; interação; produção; riscos; customização; agência; boa ordenação dos problemas; desafio e consolidação; “na hora certa” e “a pedido”;  sentidos contextualizados; frustração prazerosa; pensamento sistemático;  exploração, pensamento lateral, revisão dos  objetivos; fer...

  6. Bons video games e boa aprendizagem

    Directory of Open Access Journals (Sweden)

    James Paul Gee

    2009-01-01

    Full Text Available http://dx.doi.org/10.5007/2175-795X.2009v27n1p167   O artigo defende que os bons  videogames  incorporam bons princípios de aprendizagem, apoiados pelas  pesquisas  atuais  em Ciência Cognitiva, e os lista:  identidade; interação; produção; riscos; customização; agência; boa ordenação dos problemas; desafio e consolidação; “na hora certa” e “a pedido”;  sentidos contextualizados; frustração prazerosa; pensamento sistemático;  exploração, pensamento lateral, revisão dos  objetivos; ferramentas inteligentes e conhecimento distribuído; equipes transfuncionais e performance anterior à competência.  O artigo conclui com a seguinte pergunta: como podemos tornar  a aprendizagem, dentro e fora das escolas, mais parecida com os games no sentido de que ela use  os tipos de princípios de aprendizagem que os jovens vêem todos os dias nos bons videogames, quando e se estiverem jogando esses games de um modo reflexivo e estratégico?

  7. Franz Boas, geographer, and the problem of disciplinary identity.

    Science.gov (United States)

    Koelsch, William A

    2004-01-01

    This paper examines Franz Boas as an aspiring professional geographer during the 1880s: his Baffin Land research, his publications, his participation in geography organizations, and his struggle to attain a university appointment in geography. Frustrated by a seeming lack of opportunity for advancement in Germany, Boas explored career opportunities as a geographer in America and launched a series of unsuccessful but meaningful attempts to dominate the intellectual direction of American geography. Finally, the article reviews the circumstances surrounding Boas's appointment as an anthropologist at Clark University in 1889. Through examining Boas's own words and actions, the paper demonstrates that his professional identification with geography was lengthier and stronger than earlier accounts have suggested. It also critiques the myth of a Baffin Land "conversion" to anthropology, and delineates the circumstances of his shift from German human geography to his Americanist recasting of anthropology after 1889. Copyright 2004 Wiley Periodicals, Inc.

  8. Hemodynamic consequences of cardiac malformations in two juvenile ball pythons (Python regius).

    Science.gov (United States)

    Jensen, Bjarke; Wang, Tobias

    2009-12-01

    Two cases of bifid ventricles and cardiac malformations in juvenile ball python (Python regius) were investigated by blood pressure measurements and macro- and microscopic sectioning. A study of a normal ball python was included for reference. In both cases, all cardiac chambers were enlarged and abnormally shaped. Internal assessment of the ventricles revealed a pronounced defect of the muscular ridge, which normally is responsible for separating the systemic and pulmonary circuits. Consistent with the small muscular ridge, systolic pressures were identical in the pulmonary and systemic arteries, but, the snakes, nevertheless, lived to reach body weights severalfold of their hatchling weight.

  9. Subspectacular nematodiasis caused by a novel Serpentirhabdias species in ball pythons (Python regius).

    Science.gov (United States)

    Hausmann, J C; Mans, C; Dreyfus, J; Reavill, D R; Lucio-Forster, A; Bowman, D D

    2015-01-01

    Subspectacular nematodiasis was diagnosed in three captive-bred juvenile ball pythons (Python regius) from two unrelated facilities within a 6-month period. The snakes were presented with similar lesions, including swelling of facial, periocular and oral tissues. Bilaterally, the subspectacular spaces were distended and filled with an opaque fluid, which contained nematodes and eggs. Histopathology showed nematodes throughout the periocular tissue, subspectacular space and subcutaneous tissue of the head. The nematodes from both facilities were morphologically indistinguishable and most closely resembled Serpentirhabdias species. Morphological characterization and genetic sequencing indicate this is a previously undescribed rhabdiasid nematode. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Molecular Identification of Cryptosporidium Species from Pet Snakes in Thailand.

    Science.gov (United States)

    Yimming, Benjarat; Pattanatanang, Khampee; Sanyathitiseree, Pornchai; Inpankaew, Tawin; Kamyingkird, Ketsarin; Pinyopanuwat, Nongnuch; Chimnoi, Wissanuwat; Phasuk, Jumnongjit

    2016-08-01

    Cryptosporidium is an important pathogen causing gastrointestinal disease in snakes and is distributed worldwide. The main objectives of this study were to detect and identify Cryptosporidium species in captive snakes from exotic pet shops and snake farms in Thailand. In total, 165 fecal samples were examined from 8 snake species, boa constrictor (Boa constrictor constrictor), corn snake (Elaphe guttata), ball python (Python regius), milk snake (Lampropeltis triangulum), king snake (Lampropeltis getula), rock python (Python sebae), rainbow boa (Epicrates cenchria), and carpet python (Morelia spilota). Cryptosporidium oocysts were examined using the dimethyl sulfoxide (DMSO)-modified acid-fast staining and a molecular method based on nested-PCR, PCR-RFLP analysis, and sequencing amplification of the SSU rRNA gene. DMSO-modified acid-fast staining revealed the presence of Cryptosporidium oocysts in 12 out of 165 (7.3%) samples, whereas PCR produced positive results in 40 (24.2%) samples. Molecular characterization indicated the presence of Cryptosporidium parvum (mouse genotype) as the most common species in 24 samples (60%) from 5 species of snake followed by Cryptosporidium serpentis in 9 samples (22.5%) from 2 species of snake and Cryptosporidium muris in 3 samples (7.5%) from P. regius.

  11. Immunohistochemical Detection of a Unique Protein within Cells of Snakes Having Inclusion Body Disease, a World-Wide Disease Seen in Members of the Families Boidae and Pythonidae

    Science.gov (United States)

    Chang, Li-Wen; Fu, Ann; Wozniak, Edward; Chow, Marjorie; Duke, Diane G.; Green, Linda; Kelley, Karen; Hernandez, Jorge A.; Jacobson, Elliott R.

    2013-01-01

    Inclusion body disease (IBD) is a worldwide disease in captive boa constrictors (boa constrictor) and occasionally in other snakes of the families Boidae and Pythonidae. The exact causative agent(s) and pathogenesis are not yet fully understood. Currently, diagnosis of IBD is based on the light microscopic identification of eosinophilic intracytoplasmic inclusion bodies in hematoxylin and eosin stained tissues or blood smears. An antigenically unique 68 KDa protein was identified within the IBD inclusion bodies, called IBD protein. A validated immuno-based ante-mortem diagnostic test is needed for screening snakes that are at risk of having IBD. In this study, despite difficulties in solubilizing semi-purified inclusion bodies, utilizing hybridoma technology a mouse anti-IBD protein monoclonal antibody (MAB) was produced. The antigenic specificity of the antibody was confirmed and validated by western blots, enzyme-linked immunosorbent assay, immuno-transmission electron microscopy, and immunohistochemical staining. Paraffin embedded tissues of IBD positive and negative boa constrictors (n=94) collected from 1990 to 2011 were tested with immunohistochemical staining. In boa constrictors, the anti-IBDP MAB had a sensitivity of 83% and specificity of 100% in detecting IBD. The antibody also cross-reacted with IBD inclusion bodies in carpet pythons (Morelia spilota) and a ball python (python regius). This validated antibody can serve as a tool for the development of ante-mortem immunodiagnostic tests for IBD. PMID:24340066

  12. Immunohistochemical detection of a unique protein within cells of snakes having inclusion body disease, a world-wide disease seen in members of the families Boidae and Pythonidae.

    Directory of Open Access Journals (Sweden)

    Li-Wen Chang

    Full Text Available Inclusion body disease (IBD is a worldwide disease in captive boa constrictors (boa constrictor and occasionally in other snakes of the families Boidae and Pythonidae. The exact causative agent(s and pathogenesis are not yet fully understood. Currently, diagnosis of IBD is based on the light microscopic identification of eosinophilic intracytoplasmic inclusion bodies in hematoxylin and eosin stained tissues or blood smears. An antigenically unique 68 KDa protein was identified within the IBD inclusion bodies, called IBD protein. A validated immuno-based ante-mortem diagnostic test is needed for screening snakes that are at risk of having IBD. In this study, despite difficulties in solubilizing semi-purified inclusion bodies, utilizing hybridoma technology a mouse anti-IBD protein monoclonal antibody (MAB was produced. The antigenic specificity of the antibody was confirmed and validated by western blots, enzyme-linked immunosorbent assay, immuno-transmission electron microscopy, and immunohistochemical staining. Paraffin embedded tissues of IBD positive and negative boa constrictors (n=94 collected from 1990 to 2011 were tested with immunohistochemical staining. In boa constrictors, the anti-IBDP MAB had a sensitivity of 83% and specificity of 100% in detecting IBD. The antibody also cross-reacted with IBD inclusion bodies in carpet pythons (Morelia spilota and a ball python (python regius. This validated antibody can serve as a tool for the development of ante-mortem immunodiagnostic tests for IBD.

  13. Dysphagia after definitive radiotherapy for head and neck cancer. Correlation of dose-volume parameters of the pharyngeal constrictor muscles

    Energy Technology Data Exchange (ETDEWEB)

    Deantonio, L.; Masini, L. [University Hospital ' Maggiore della Carita' , Novara (Italy). Radiotherapy; Brambilla, M. [University Hospital ' Maggiore della Carita' , Novara (Italy). Medical Physics; Pia, F. [University Hospital ' Maggiore della Carita' , Novara (Italy). Otolaryngology; University of ' Piemonte Orientale' , Novara (Italy). Dept. of Medical Sciences; Krengli, M. [University Hospital ' Maggiore della Carita' , Novara (Italy). Radiotherapy; University of ' Piemonte Orientale' , Novara (Italy). Dept. of Translational Medicine and BRMA

    2013-03-15

    Background: Dysphagia is a complication of head and neck cancer patients undergoing radiotherapy (RT). We analysed frequency and severity of swallowing dysfunction and correlated these findings with dose-volume histograms (DVHs) of the pharyngeal constrictor muscles. Methods: A total of 50 patients treated by radical RT were enrolled. DVHs of constrictor muscles were correlated with acute and late dysphagia and with the items of three quality of life questionnaires. Results: Mean dose to superior and middle constrictor muscles (SCM, MCM), partial volume of SCM and MCM receiving a dose {>=} 50 Gy dose to the whole constrictor muscles {>=} 60 Gy and tumour location were associated to late dysphagia at univariate analysis. Mean dose to the MCM was the only statistically significant predictor of late dysphagia at the multivariable analysis. Conclusion: The study shows a significant relationship between long-term dysphagia and mean doses to SCM, MCM, whole constrictor muscles, and oropharyngeal tumour. This finding suggests a potential advantage in reducing the RT dose to swallowing structures to avoid severe dysphagia. (orig.)

  14. Dysphagia after definitive radiotherapy for head and neck cancer. Correlation of dose-volume parameters of the pharyngeal constrictor muscles

    International Nuclear Information System (INIS)

    Deantonio, L.; Masini, L.; Brambilla, M.; Pia, F.; University of 'Piemonte Orientale', Novara; Krengli, M.; University of 'Piemonte Orientale', Novara

    2013-01-01

    Background: Dysphagia is a complication of head and neck cancer patients undergoing radiotherapy (RT). We analysed frequency and severity of swallowing dysfunction and correlated these findings with dose-volume histograms (DVHs) of the pharyngeal constrictor muscles. Methods: A total of 50 patients treated by radical RT were enrolled. DVHs of constrictor muscles were correlated with acute and late dysphagia and with the items of three quality of life questionnaires. Results: Mean dose to superior and middle constrictor muscles (SCM, MCM), partial volume of SCM and MCM receiving a dose ≥ 50 Gy dose to the whole constrictor muscles ≥ 60 Gy and tumour location were associated to late dysphagia at univariate analysis. Mean dose to the MCM was the only statistically significant predictor of late dysphagia at the multivariable analysis. Conclusion: The study shows a significant relationship between long-term dysphagia and mean doses to SCM, MCM, whole constrictor muscles, and oropharyngeal tumour. This finding suggests a potential advantage in reducing the RT dose to swallowing structures to avoid severe dysphagia. (orig.)

  15. Saccular lung cannulation in a ball python (Python regius) to treat a tracheal obstruction.

    Science.gov (United States)

    Myers, Debbie A; Wellehan, James F X; Isaza, Ramiro

    2009-03-01

    An adult male ball python (Python regius) presented in a state of severe dyspnea characterized by open-mouth breathing and vertical positioning of the head and neck. The animal had copious discharge in the tracheal lumen acting as an obstruction. A tube was placed through the body wall into the caudal saccular aspect of the lung to allow the animal to breathe while treatment was initiated. The ball python's dyspnea immediately improved. Diagnostics confirmed a bacterial respiratory infection with predominantly Providencia rettgeri. The saccular lung (air sac) tube was removed after 13 days. Pulmonary endoscopy before closure showed minimal damage with a small amount of hemorrhage in the surrounding muscle tissue. Respiratory disease is a common occurrence in captive snakes and can be associated with significant morbidity and mortality. Saccular lung cannulation is a relatively simple procedure that can alleviate tracheal narrowing or obstruction, similar to air sac cannulation in birds.

  16. Development and application of the BOA code in Spain

    International Nuclear Information System (INIS)

    Tortuero Lopez, C.; Doncel Gutierrez, N.; Culebras, F.

    2012-01-01

    The BOA code allows to quantitatively establish the level of risk of Axial Offset Anomaly and increased deposition of crud on the basis of specific conditions in each case. For this reason, the code is parameterized according to the individual characteristics of each plant. This paper summarizes the results obtained in the implementation of the code, as well as its future perspective.

  17. Connection coefficients between Boas-Buck polynomial sets

    Science.gov (United States)

    Cheikh, Y. Ben; Chaggara, H.

    2006-07-01

    In this paper, a general method to express explicitly connection coefficients between two Boas-Buck polynomial sets is presented. As application, we consider some generalized hypergeometric polynomials, from which we derive some well-known results including duplication and inversion formulas.

  18. Development of behavioural profile in the Northern common boa (Boa imperator): Repeatable independent traits or personality?

    Science.gov (United States)

    Šimková, Olga; Frýdlová, Petra; Žampachová, Barbora; Frynta, Daniel; Landová, Eva

    2017-01-01

    Recent studies of animal personality have focused on its proximate causation and ecological and evolutionary significance in particular, but the question of its development was largely overlooked. The attributes of personality are defined as between-individual differences in behaviour, which are consistent over time (differential consistency) and contexts (contextual generality) and both can be affected by development. We assessed several candidates for personality variables measured in various tests with different contexts over several life-stages (juveniles, older juveniles, subadults and adults) in the Northern common boa. Variables describing foraging/feeding decision and some of the defensive behaviours expressed as individual average values are highly repeatable and consistent. We found two main personality axes—one associated with foraging/feeding and the speed of decision, the other reflecting agonistic behaviour. Intensity of behaviour in the feeding context changes during development, but the level of agonistic behaviour remains the same. The juveniles and adults have a similar personality structure, but there is a period of structural change of behaviour during the second year of life (subadults). These results require a new theoretical model to explain the selection pressures resulting in this developmental pattern of personality. We also studied the proximate factors and their relationship to behavioural characteristics. Physiological parameters (heart and breath rate stress response) measured in adults clustered with variables concerning the agonistic behavioural profile, while no relationship between the juvenile/adult body size and personality concerning feeding/foraging and the agonistic behavioural profile was found. Our study suggests that it is important for studies of personality development to focus on both the structural and differential consistency, because even though behaviour is differentially consistent, the structure can change. PMID

  19. Development of behavioural profile in the Northern common boa (Boa imperator: Repeatable independent traits or personality?

    Directory of Open Access Journals (Sweden)

    Olga Šimková

    Full Text Available Recent studies of animal personality have focused on its proximate causation and ecological and evolutionary significance in particular, but the question of its development was largely overlooked. The attributes of personality are defined as between-individual differences in behaviour, which are consistent over time (differential consistency and contexts (contextual generality and both can be affected by development. We assessed several candidates for personality variables measured in various tests with different contexts over several life-stages (juveniles, older juveniles, subadults and adults in the Northern common boa. Variables describing foraging/feeding decision and some of the defensive behaviours expressed as individual average values are highly repeatable and consistent. We found two main personality axes-one associated with foraging/feeding and the speed of decision, the other reflecting agonistic behaviour. Intensity of behaviour in the feeding context changes during development, but the level of agonistic behaviour remains the same. The juveniles and adults have a similar personality structure, but there is a period of structural change of behaviour during the second year of life (subadults. These results require a new theoretical model to explain the selection pressures resulting in this developmental pattern of personality. We also studied the proximate factors and their relationship to behavioural characteristics. Physiological parameters (heart and breath rate stress response measured in adults clustered with variables concerning the agonistic behavioural profile, while no relationship between the juvenile/adult body size and personality concerning feeding/foraging and the agonistic behavioural profile was found. Our study suggests that it is important for studies of personality development to focus on both the structural and differential consistency, because even though behaviour is differentially consistent, the structure can

  20. Development of behavioural profile in the Northern common boa (Boa imperator): Repeatable independent traits or personality?

    Science.gov (United States)

    Šimková, Olga; Frýdlová, Petra; Žampachová, Barbora; Frynta, Daniel; Landová, Eva

    2017-01-01

    Recent studies of animal personality have focused on its proximate causation and ecological and evolutionary significance in particular, but the question of its development was largely overlooked. The attributes of personality are defined as between-individual differences in behaviour, which are consistent over time (differential consistency) and contexts (contextual generality) and both can be affected by development. We assessed several candidates for personality variables measured in various tests with different contexts over several life-stages (juveniles, older juveniles, subadults and adults) in the Northern common boa. Variables describing foraging/feeding decision and some of the defensive behaviours expressed as individual average values are highly repeatable and consistent. We found two main personality axes-one associated with foraging/feeding and the speed of decision, the other reflecting agonistic behaviour. Intensity of behaviour in the feeding context changes during development, but the level of agonistic behaviour remains the same. The juveniles and adults have a similar personality structure, but there is a period of structural change of behaviour during the second year of life (subadults). These results require a new theoretical model to explain the selection pressures resulting in this developmental pattern of personality. We also studied the proximate factors and their relationship to behavioural characteristics. Physiological parameters (heart and breath rate stress response) measured in adults clustered with variables concerning the agonistic behavioural profile, while no relationship between the juvenile/adult body size and personality concerning feeding/foraging and the agonistic behavioural profile was found. Our study suggests that it is important for studies of personality development to focus on both the structural and differential consistency, because even though behaviour is differentially consistent, the structure can change.

  1. FREUD, JUNG AND BOAS: THE PSYCHOANALYTIC ENGAGEMENT WITH ANTHROPOLOGY REVISITED.

    Science.gov (United States)

    Kenny, Robert

    2015-06-20

    Sigmund Freud's and C. G. Jung's turn to evolutionist anthropological material after 1909 is usually seen as a logical progression of their long-term interest in such material. It is also seen that they used this material ignorant of the significant challenges to the evolutionist paradigm underpinning such material, in particular the challenges led by Franz Boas. This paper argues otherwise: that both psychologists' turnings to such material was a new development, that neither had shown great interest in such material before 1909, and that their turnings to such material, far from being taken in ignorance of the challenges to evolutionist anthropology, were engagements with those challenges, because the evolutionist paradigm lay at the base of psychoanalysis. It argues that it is no coincidence that this engagement occurred after their return from America in 1909, where they had come into first-hand contact with the challenges of Franz Boas.

  2. Freud, Jung and Boas: the psychoanalytic engagement with anthropology revisited

    Science.gov (United States)

    Kenny, Robert

    2015-01-01

    Sigmund Freud's and C. G. Jung's turn to evolutionist anthropological material after 1909 is usually seen as a logical progression of their long-term interest in such material. It is also seen that they used this material ignorant of the significant challenges to the evolutionist paradigm underpinning such material, in particular the challenges led by Franz Boas. This paper argues otherwise: that both psychologists' turnings to such material was a new development, that neither had shown great interest in such material before 1909, and that their turnings to such material, far from being taken in ignorance of the challenges to evolutionist anthropology, were engagements with those challenges, because the evolutionist paradigm lay at the base of psychoanalysis. It argues that it is no coincidence that this engagement occurred after their return from America in 1909, where they had come into first-hand contact with the challenges of Franz Boas. PMID:26665301

  3. BOA, Beam Optics Analyzer A Particle-In-Cell Code

    International Nuclear Information System (INIS)

    Bui, Thuc

    2007-01-01

    The program was tasked with implementing time dependent analysis of charges particles into an existing finite element code with adaptive meshing, called Beam Optics Analyzer (BOA). BOA was initially funded by a DOE Phase II program to use the finite element method with adaptive meshing to track particles in unstructured meshes. It uses modern programming techniques, state-of-the-art data structures, so that new methods, features and capabilities are easily added and maintained. This Phase II program was funded to implement plasma simulations in BOA and extend its capabilities to model thermal electrons, secondary emissions, self magnetic field and implement a more comprehensive post-processing and feature-rich GUI. The program was successful in implementing thermal electrons, secondary emissions, and self magnetic field calculations. The BOA GUI was also upgraded significantly, and CCR is receiving interest from the microwave tube and semiconductor equipment industry for the code. Implementation of PIC analysis was partially successful. Computational resource requirements for modeling more than 2000 particles begin to exceed the capability of most readily available computers. Modern plasma analysis typically requires modeling of approximately 2 million particles or more. The problem is that tracking many particles in an unstructured mesh that is adapting becomes inefficient. In particular memory requirements become excessive. This probably makes particle tracking in unstructured meshes currently unfeasible with commonly available computer resources. Consequently, Calabazas Creek Research, Inc. is exploring hybrid codes where the electromagnetic fields are solved on the unstructured, adaptive mesh while particles are tracked on a fixed mesh. Efficient interpolation routines should be able to transfer information between nodes of the two meshes. If successfully developed, this could provide high accuracy and reasonable computational efficiency.

  4. BOA II: pipe-asbestos insulation removal system

    International Nuclear Information System (INIS)

    Schempf, H.; Mutschler; Boehmke, S.; Chemel, B.; Piepgras, C.

    1996-01-01

    BOA system is a mobile pipe-external robotic crawler used to remotely strip and bag asbestos-containing lagging and insulation materials from various diameter pipes in (primarily) industrial installations. Steam and process lines within the DOE weapons complex warrant the use of a remote device due to high labor costs and high level of radioactive contamination, making manual removal costly and inefficient. Currently targeted facilities for demonstration and remediation are Fernald in Ohio and Oak Ridge in Tennessee

  5. BOA: Asbestos pipe insulation removal robot system. Phase 1

    Energy Technology Data Exchange (ETDEWEB)

    Schempf, H.; Bares, J.E.

    1995-02-01

    The project described in this report targets the development of a mechanized system for safe, cost-efficient and automated abatement of asbestos containing materials used as pipe insulation. Based on several key design criteria and site visits, a proof-of-concept prototype robot system, dubbed BOA, was designed and built, which automatically strips the lagging and insulation from the pipes, and encapsulates them under complete vacuum operation. The system can operate on straight runs of piping in horizontal or vertical orientations. Currently we are limited to four-inch diameter piping without obstacles as well as a somewhat laborious emplacement and removal procedure -- restrictions to be alleviated through continued development. BOA removed asbestos at a rate of 4-5 ft./h compared to 3 ft./h for manual removal of asbestos with a 3-person crew. The containment and vacuum system on BOA was able to achieve the regulatory requirement for airborne fiber emissions of 0.01 fibers/ccm/ 8-hr. shift. This program consists of two phases. The first phase was completed and a demonstration was given to a review panel, consisting of DOE headquarters and site representatives as well as commercial abatement industry representatives. Based on the technical and programmatic recommendations drafted, presented and discussed during the review meeting, a new plan for the Phase II effort of this project was developed. Phase 11 will consist of a 26-month effort, with an up-front 4-month site-, market-, cost/benefit and regulatory study before the next BOA robot (14 months) is built, and then deployed and demonstrated (3 months) at a DOE site (such as Fernald or Oak Ridge) by the beginning of FY`97.

  6. Morphological respiratory diffusion capacity of the lungs of ball pythons (Python regius).

    Science.gov (United States)

    Starck, J Matthias; Aupperle, Heike; Kiefer, Ingmar; Weimer, Isabel; Krautwald-Junghanns, Maria-Elisabeth; Pees, Michael

    2012-08-01

    This study aims at a functional and morphological characterization of the lung of a boid snake. In particular, we were interested to see if the python's lungs are designed with excess capacity as compared to resting and working oxygen demands. Therefore, the morphological respiratory diffusion capacity of ball pythons (Python regius) was examined following a stereological, hierarchically nested approach. The volume of the respiratory exchange tissue was determined using computed tomography. Tissue compartments were quantified using stereological methods on light microscopic images. The tissue diffusion barrier for oxygen transport was characterized and measured using transmission electron micrographs. We found a significant negative correlation between body mass and the volume of respiratory tissue; the lungs of larger snakes had relatively less respiratory tissue. Therefore, mass-specific respiratory tissue was calculated to exclude effects of body mass. The volume of the lung that contains parenchyma was 11.9±5.0mm(3)g(-1). The volume fraction, i.e., the actual pulmonary exchange tissue per lung parenchyma, was 63.22±7.3%; the total respiratory surface was, on average, 0.214±0.129m(2); it was significantly negatively correlated to body mass, with larger snakes having proportionally smaller respiratory surfaces. For the air-blood barrier, a harmonic mean of 0.78±0.05μm was found, with the epithelial layer representing the thickest part of the barrier. Based on these findings, a median diffusion capacity of the tissue barrier ( [Formula: see text] ) of 0.69±0.38ml O(2)min(-1)mmHg(-1) was calculated. Based on published values for blood oxygen concentration, a total oxygen uptake capacity of 61.16mlO(2)min(-1)kg(-1) can be assumed. This value exceeds the maximum demand for oxygen in ball pythons by a factor of 12. We conclude that healthy individuals of P. regius possess a considerable spare capacity for tissue oxygen exchange. Copyright © 2012 Elsevier Gmb

  7. Respiratory disease in ball pythons (Python regius) experimentally infected with ball python nidovirus.

    Science.gov (United States)

    Hoon-Hanks, Laura L; Layton, Marylee L; Ossiboff, Robert J; Parker, John S L; Dubovi, Edward J; Stenglein, Mark D

    2018-04-01

    Circumstantial evidence has linked a new group of nidoviruses with respiratory disease in pythons, lizards, and cattle. We conducted experimental infections in ball pythons (Python regius) to test the hypothesis that ball python nidovirus (BPNV) infection results in respiratory disease. Three ball pythons were inoculated orally and intratracheally with cell culture isolated BPNV and two were sham inoculated. Antemortem choanal, oroesophageal, and cloacal swabs and postmortem tissues of infected snakes were positive for viral RNA, protein, and infectious virus by qRT-PCR, immunohistochemistry, western blot and virus isolation. Clinical signs included oral mucosal reddening, abundant mucus secretions, open-mouthed breathing, and anorexia. Histologic lesions included chronic-active mucinous rhinitis, stomatitis, tracheitis, esophagitis and proliferative interstitial pneumonia. Control snakes remained negative and free of clinical signs throughout the experiment. Our findings establish a causal relationship between nidovirus infection and respiratory disease in ball pythons and shed light on disease progression and transmission. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  8. Food composition influences metabolism, heart rate and organ growth during digestion in Python regius.

    Science.gov (United States)

    Henriksen, Poul Secher; Enok, Sanne; Overgaard, Johannes; Wang, Tobias

    2015-05-01

    Digestion in pythons is associated with a large increase in oxygen consumption (SDA), increased cardiac output and growth in visceral organs assisting in digestion. The processes leading to the large postprandial rise in metabolism in snakes is subject to opposing views. Gastric work, protein synthesis and organ growth have each been speculated to be major contributors to the SDA. To investigate the role of food composition on SDA, heart rate (HR) and organ growth, 48 ball pythons (Python regius) were fed meals of either fat, glucose, protein or protein combined with carbonate. Our study shows that protein, in the absence or presence of carbonate causes a large SDA response, while glucose caused a significantly smaller SDA response and digestion of fat failed to affect metabolism. Addition of carbonate to the diet to stimulate gastric acid secretion did not increase the SDA response. These results support protein synthesis as a major contributor to the SDA response and show that increased gastric acid secretion occurs at a low metabolic cost. The increase in metabolism was supported by tachycardia caused by altered autonomic regulation as well as an increased non-adrenergic, non-cholinergic (NANC) tone in response to all diets, except for the lipid meal. Organ growth only occurred in the small intestine and liver in snakes fed on a high protein diet. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. Size, but not experience, affects the ontogeny of constriction performance in ball pythons (Python regius).

    Science.gov (United States)

    Penning, David A; Dartez, Schuyler F

    2016-03-01

    Constriction is a prey-immobilization technique used by many snakes and is hypothesized to have been important to the evolution and diversification of snakes. However, very few studies have examined the factors that affect constriction performance. We investigated constriction performance in ball pythons (Python regius) by evaluating how peak constriction pressure is affected by snake size, sex, and experience. In one experiment, we tested the ontogenetic scaling of constriction performance and found that snake diameter was the only significant factor determining peak constriction pressure. The number of loops applied in a coil and its interaction with snake diameter did not significantly affect constriction performance. Constriction performance in ball pythons scaled differently than in other snakes that have been studied, and medium to large ball pythons are capable of exerting significantly higher pressures than those shown to cause circulatory arrest in prey. In a second experiment, we tested the effects of experience on constriction performance in hatchling ball pythons over 10 feeding events. By allowing snakes in one test group to gain constriction experience, and manually feeding snakes under sedation in another test group, we showed that experience did not affect constriction performance. During their final (10th) feedings, all pythons constricted similarly and with sufficiently high pressures to kill prey rapidly. At the end of the 10 feeding trials, snakes that were allowed to constrict were significantly smaller than their non-constricting counterparts. © 2016 Wiley Periodicals, Inc.

  10. The spectacle of the ball python (Python regius): a morphological description.

    Science.gov (United States)

    Da Silva, Mari-Ann O; Heegaard, Steffen; Wang, Tobias; Nyengaard, Jens R; Bertelsen, Mads F

    2014-05-01

    A detailed morphological description of the spectacle of the ball python (Python regius) is provided. The eyes of 21 snakes were examined by light microscopy and/or transmission electron microscopy. Additionally, eyes of nine live snakes were examined using optical coherence tomography (OCT) and Scheimpflug scanning (Pentacam). The spectacle consists of three layers: outer epithelium, stroma and inner epithelium. The outer epithelium is made up of flat basal cells overlaid by keratin, the stroma consists of organized layers of collagen fibrils with interweaving nerve fibers and blood vessels, and the inner epithelium holds squamous cells containing vesicles and microvilli. At the rim of the spectacle, there is a transition zone, where the spectacle merges with the epidermis and dermis of the periocular scales. This zone is characterized by a greater height of the basal cells of the outer epithelium and a less orderly organization of the stroma compared with the spectacle proper. The thickness of the spectacle was uniform throughout. It averaged 96 ± 10 µm in histological specimens and 108 ± 13 µm using OCT. The subspectacular space was extremely narrow in the live snakes; however, the space was visible at the periphery of the spectacle with OCT. Copyright © 2013 Wiley Periodicals, Inc.

  11. Effect of laser treatment on first-intention incisional wound healing in ball pythons (Python regius).

    Science.gov (United States)

    Cole, Grayson L; Lux, Cassie N; Schumacher, Juergen P; Seibert, Rachel L; Sadler, Ryan A; Henderson, Andrea L; Odoi, Agricola; Newkirk, Kim M

    2015-10-01

    To evaluate effects of laser treatment on incisional wound healing in ball pythons (Python regius). 6 healthy adult ball pythons. Snakes were sedated, a skin biopsy specimen was collected for histologic examination, and eight 2-cm skin incisions were made in each snake; each incision was closed with staples (day 0). Gross evaluation of all incision sites was performed daily for 30 days, and a wound score was assigned. Four incisions of each snake were treated (5 J/cm(2) and a wavelength of 980 nm on a continuous wave sequence) by use of a class 4 laser once daily for 7 consecutive days; the other 4 incisions were not treated. Two excisional skin biopsy specimens (1 control and 1 treatment) were collected from each snake on days 2, 7, 14, and 30 and evaluated microscopically. Scores were assigned for total inflammation, degree of fibrosis, and collagen maturity. Generalized linear models were used to investigate the effect of treatment on each variable. Wound scores for laser-treated incisions were significantly better than scores for control incisions on day 2 but not at other time points. There were no significant differences in necrosis, fibroplasia, inflammation, granuloma formation, or bacterial contamination between control and treatment groups. Collagen maturity was significantly better for the laser-treated incisions on day 14. Laser treatment resulted in a significant increase in collagen maturity at day 14 but did not otherwise significantly improve healing of skin incisions.

  12. Improved cardiac filling facilitates the postprandial elevation of stroke volume in Python regius.

    Science.gov (United States)

    Enok, Sanne; Leite, Gabriella S P C; Leite, Cléo A C; Gesser, Hans; Hedrick, Michael S; Wang, Tobias

    2016-10-01

    To accommodate the pronounced metabolic response to digestion, pythons increase heart rate and elevate stroke volume, where the latter has been ascribed to a massive and fast cardiac hypertrophy. However, numerous recent studies show that heart mass rarely increases, even upon ingestion of large meals, and we therefore explored the possibility that a rise in mean circulatory filling pressure (MCFP) serves to elevate venous pressure and cardiac filling during digestion. To this end, we measured blood flows and pressures in anaesthetized Python regius The anaesthetized snakes exhibited the archetypal tachycardia as well as a rise in both venous pressure and MCFP that fully account for the approximate doubling of stroke volume. There was no rise in blood volume and the elevated MCFP must therefore stem from increased vascular tone, possibly by means of increased sympathetic tone on the veins. Furthermore, although both venous pressure and MCFP increased during volume loading, there was no evidence that postprandial hearts were endowed with an additional capacity to elevate stroke volume. In vitro measurements of force development of paced ventricular strips also failed to reveal signs of increased contractility, but the postprandial hearts had higher activities of cytochrome oxidase and pyruvate kinase, which probably serves to sustain the rise in cardiac work during digestion. © 2016. Published by The Company of Biologists Ltd.

  13. Absence of inspiratory laryngeal constrictor muscle activity during nasal neurally adjusted ventilatory assist in newborn lambs.

    Science.gov (United States)

    Hadj-Ahmed, Mohamed Amine; Samson, Nathalie; Bussières, Marie; Beck, Jennifer; Praud, Jean-Paul

    2012-07-01

    In nonsedated newborn lambs, nasal pressure support ventilation (nPSV) can lead to an active glottal closure in early inspiration, which can limit lung ventilation and divert air into the digestive system, with potentially deleterious consequences. During volume control ventilation (nVC), glottal closure is delayed to the end of inspiration, suggesting that it is reflexly linked to the maximum value of inspiratory pressure. Accordingly, the aim of the present study was to test whether inspiratory glottal closure develops at the end of inspiration during nasal neurally adjusted ventilatory assist (nNAVA), an increasingly used ventilatory mode where maximal pressure is also reached at the end of inspiration. Polysomnographic recordings were performed in eight nonsedated, chronically instrumented lambs, which were ventilated with progressively increasing levels of nPSV and nNAVA in random order. States of alertness, diaphragm, and glottal muscle electrical activity, tracheal pressure, Spo(2), tracheal Pet(CO(2)), and respiratory inductive plethysmography were continuously recorded. Although phasic inspiratory glottal constrictor electrical activity appeared during nPSV in 5 of 8 lambs, it was never observed at any nNAVA level in any lamb, even at maximal achievable nNAVA levels. In addition, a decrease in Pco(2) was neither necessary nor sufficient for the development of inspiratory glottal constrictor activity. In conclusion, nNAVA does not induce active inspiratory glottal closure, in contrast to nPSV and nVC. We hypothesize that this absence of inspiratory activity is related to the more physiological airway pressurization during nNAVA, which tightly follows diaphragm electrical activity throughout inspiration.

  14. BOA: Asbestos Pipe-Insulation Abatement Robot System

    International Nuclear Information System (INIS)

    Schempf, H.

    1996-01-01

    The BOA system is a mobile pipe-external robotic crawler used to remotely strip and bag asbestos-containing lagging and insulation materials (ACLIM) from various diameter pipes in (primarily) industrial installations. Steam and process lines within the DOE weapons complex warrant the use of a remote device due to the high labor costs and high level of radioactive contamination, making manual removal extremely costly and highly inefficient. Currently targeted facilities for demonstration and remediation are Fernald in Ohio and Oak Ridge in Tennessee

  15. BOA: Pipe-asbestos insulation removal robot system

    Energy Technology Data Exchange (ETDEWEB)

    Schempf, H.; Bares, J.; Schnorr, W. [Carnegie Mellon Univ., Pittsburgh, PA (United States)

    1995-10-01

    The BOA system is a mobile pipe-external robotic crawler used to remotely strip and bag asbestos-containing lagging and insulation materials (ACLIM) from various diameter pipes in (primarily) industrial installations. Steam and process lines within the DOE weapons complex warrant the use of a remote device due to the high labor costs and high level of radioactive contamination, making manual removal extremely costly and highly inefficient. Currently targeted facilities for demonstration and remediation are Fernald in Ohio and Oak Ridge in Tennessee.

  16. BOA: Pipe-asbestos insulation removal robot system

    International Nuclear Information System (INIS)

    Schempf, H.; Bares, J.; Schnorr, W.

    1995-01-01

    The BOA system is a mobile pipe-external robotic crawler used to remotely strip and bag asbestos-containing lagging and insulation materials (ACLIM) from various diameter pipes in (primarily) industrial installations. Steam and process lines within the DOE weapons complex warrant the use of a remote device due to the high labor costs and high level of radioactive contamination, making manual removal extremely costly and highly inefficient. Currently targeted facilities for demonstration and remediation are Fernald in Ohio and Oak Ridge in Tennessee

  17. Conformational risk factors of brachycephalic obstructive airway syndrome (BOAS) in pugs, French bulldogs, and bulldogs.

    Science.gov (United States)

    Liu, Nai-Chieh; Troconis, Eileen L; Kalmar, Lajos; Price, David J; Wright, Hattie E; Adams, Vicki J; Sargan, David R; Ladlow, Jane F

    2017-01-01

    Extremely brachycephalic, or short-muzzled, dog breeds such as pugs, French bulldogs, and bulldogs are prone to the conformation-related respiratory disorder-brachycephalic obstructive airway syndrome (BOAS). Affected dogs present with a wide range of clinical signs from snoring and exercise intolerance, to life-threatening events such as syncope. In this study, conformational risk factors for BOAS that could potentially aid in breeding away from BOAS were sought. Six hundred and four pugs, French bulldogs, and bulldogs were included in the study. Soft tape measurements of the head and body were used and the inter-observer reproducibility was evaluated. Breed-specific models were developed to assess the associations between the conformational factors and BOAS status based on functional grading. The models were further validated by means of a BOAS index, which is an objective measurement of respiratory function using whole-body barometric plethysmography. The final models have good predictive power for discriminating BOAS (-) and BOAS (+) phenotypes indicated by the area under the curve values of >80% on the receiver operating curves. When other factors were controlled, stenotic nostrils were associated with BOAS in all three breeds; pugs and bulldogs with higher body condition scores (BCS) had a higher risk of developing BOAS. Among the standardized conformational measurements (i.e. craniofacial ratio (CFR), eye width ratio (EWR), skull index (SI), neck girth ratio (NGR), and neck length ratio (NLR)), for pugs EWR and SI, for French bulldogs NGR and NLR, and for bulldogs SI and NGR showed significant associations with BOAS status. However, the NGR in bulldogs was the only significant predictor that also had satisfactory inter-observer reproducibility. A NGR higher than 0.71 in male bulldogs was predictive of BOAS with approximately 70% sensitivity and specificity. In conclusion, stenotic nostrils, BCS, and NGR were found to be valid, easily applicable predictors

  18. BOA: Pipe-asbestos insulation removal robot system

    International Nuclear Information System (INIS)

    Schempf, H.; Bares, J.; Mutschler, E.

    1995-01-01

    This paper describes the BOA system, a mobile pipe-external crawler used to remotely strip and bag (possibly contaminated) asbestos-containing lagging and insulation materials (ACLIM) from various diameter pipes in (primarily) industrial installations across the DOE weapons complex. The mechanical removal of ACLIM is very cost-effective due to the relatively low productivity and high cost involved in human removal scenarios. BOA, a mechanical system capable of removing most forms of lagging (paper, plaster, aluminum sheet, clamps, screws and chicken-wire), and insulation (paper, tar, asbestos fiber, mag-block) uses a circular cutter and compression paddles to cut and strip the insulation off the pipe through compression, while a HEPA-filter and encapsulant system maintain a certifiable vacuum and moisture content inside the system and on the pipe, respectively. The crawler system has been built and is currently undergoing testing. Key design parameters and performance parameters are developed and used in performance testing. Since the current system is a testbed, we also discuss future enhancements and outline two deployment scenarios (robotic and manual) for the final system to be designed and completed by the end of FY '95. An on-site demonstration is currently planned for Fernald in Ohio and Oak Ridge in Tennessee

  19. Ecological specialization and morphological diversification in Greater Antillean boas.

    Science.gov (United States)

    Reynolds, R Graham; Collar, David C; Pasachnik, Stesha A; Niemiller, Matthew L; Puente-Rolón, Alberto R; Revell, Liam J

    2016-08-01

    Colonization of islands can dramatically influence the evolutionary trajectories of organisms, with both deterministic and stochastic processes driving adaptation and diversification. Some island colonists evolve extremely large or small body sizes, presumably in response to unique ecological circumstances present on islands. One example of this phenomenon, the Greater Antillean boas, includes both small (<90 cm) and large (4 m) species occurring on the Greater Antilles and Bahamas, with some islands supporting pairs or trios of body-size divergent species. These boas have been shown to comprise a monophyletic radiation arising from a Miocene dispersal event to the Greater Antilles, though it is not known whether co-occurrence of small and large species is a result of dispersal or in situ evolution. Here, we provide the first comprehensive species phylogeny for this clade combined with morphometric and ecological data to show that small body size evolved repeatedly on separate islands in association with specialization in substrate use. Our results further suggest that microhabitat specialization is linked to increased rates of head shape diversification among specialists. Our findings show that ecological specialization following island colonization promotes morphological diversity through deterministic body size evolution and cranial morphological diversification that is contingent on island- and species-specific factors. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

  20. Functional morphology and patterns of blood flow in the heart of Python regius.

    Science.gov (United States)

    Starck, J Matthias

    2009-06-01

    circulation in Python regius.

  1. Differential behavioural responses to venlafaxine exposure route, warming and acidification in juvenile fish (Argyrosomus regius).

    Science.gov (United States)

    Maulvault, Ana Luísa; Santos, Lúcia H M L M; Paula, José Ricardo; Camacho, Carolina; Pissarra, Vasco; Fogaça, Fabiola; Barbosa, Vera; Alves, Ricardo; Ferreira, Pedro Pousão; Barceló, Damià; Rodriguez-Mozaz, Sara; Marques, António; Diniz, Mário; Rosa, Rui

    2018-09-01

    Antidepressants, such as venlafaxine (VFX), which are considered emerging environmental pollutants, are increasingly more present in the marine environment, and recent evidence suggest that they might have adverse effects on fish behaviour. Furthermore, altered environmental conditions associated to climate change (e.g. warming and acidification) can also have a determinant role on fish behaviour, fitness and survival. Yet, the underlying interactions between these environmental stressors (pharmaceuticals exposure and climate change) are still far from being fully understood. The aim of this study was to assess behavioural responses (in juvenile meagre (Argyrosomus regius) exposed to VFX via water ([VFX] ~20μgL -1 ) and via dietary sources ([VFX] ~160μgkg -1 dry weight), as well as to increased temperature (ΔT°C=+5°C) and high CO 2 levels (ΔpCO 2 ~1000μatm; equivalent to ΔpH=-0.4units). Overall, VFX bioaccumulation in fish plasma was enhanced under the combination of warming and acidification. VFX triggered fish exploration, whereas fish activity and shoal cohesion were reduced. Acidification alone decreased fish exploration and shoal cohesion, and reversed fish preference to turn leftwards compared to control conditions. Such alterations were further enhanced by VFX exposure. The combination of warming and acidification also reduced shoal cohesion and loss of lateralization, regardless of VFX exposure. The distinct behaviour observed when VFX contamination, acidification and warming acted alone or in combination highlighted the need to consider the likely interactive effects of seawater warming and acidification in future research regarding the toxicological aspects of chemical contaminants. Copyright © 2018. Published by Elsevier B.V.

  2. The influence of mechanical ventilation on physiological parameters in ball pythons (Python regius).

    Science.gov (United States)

    Jakobsen, Sashia L; Williams, Catherine J A; Wang, Tobias; Bertelsen, Mads F

    2017-05-01

    Mechanical ventilation is widely recommended for reptiles during anesthesia, and while it is well-known that their low ectothermic metabolism requires much lower ventilation than in mammals, very little is known about the influence of ventilation protocol on the recovery from anesthesia. Here, 15 ball pythons (Python regius) were induced and maintained with isoflurane for 60min at one of three ventilation protocols (30, 125, or 250mlmin -1 kg -1 body mass) while an arterial catheter was inserted, and ventilation was then continued on 100% oxygen at the specified rate until voluntary extubation. Mean arterial blood pressure and heart rate (HR) were measured, and arterial blood samples collected at 60, 80, 180min and 12 and 24h after intubation. In all three groups, there was evidence of a metabolic acidosis, and snakes maintained at 30mlmin -1 kg -1 experienced an additional respiratory acidosis, while the two other ventilation protocols resulted in normal or low arterial PCO 2 . In general, normal acid-base status was restored within 12h in all three protocols. HR increased by 143±64% during anesthesia with high mechanical ventilation (250mlmin -1 kg -1 ) in comparison with recovered values. Recovery times after mechanical ventilation at 30, 125, or 250mlmin -1 kg -1 were 289±70, 126±16, and 68±7min, respectively. Mild overventilation may result in a faster recovery, and the associated lowering of arterial PCO 2 normalised arterial pH in the face of metabolic acidosis. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Spectral domain optical coherence tomography imaging of spectacular ecdysis in the royal python (Python regius).

    Science.gov (United States)

    Tusler, Charlotte A; Maggs, David J; Kass, Philip H; Paul-Murphy, Joanne R; Schwab, Ivan R; Murphy, Christopher J

    2015-01-01

    To describe using spectral domain optical coherence tomography (SD-OCT), digital slit-lamp biomicroscopy, and external photography, changes in the ophidian cuticle, spectacle, and cornea during ecdysis. Four normal royal pythons (Python regius). Snakes were assessed once daily throughout a complete shed cycle using nasal, axial, and temporal SD-OCT images, digital slit-lamp biomicroscopy, and external photography. Spectral domain optical coherence tomography (SD-OCT) images reliably showed the spectacular cuticle and stroma, subcuticular space (SCS), cornea, anterior chamber, iris, and Schlemm's canal. When visible, the subspectacular space (SSS) was more distended peripherally than axially. Ocular surface changes throughout ecdysis were relatively conserved among snakes at all three regions imaged. From baseline (7 days following completion of a full cycle), the spectacle gradually thickened before separating into superficial cuticular and deep, hyper-reflective stromal components, thereby creating the SCS. During spectacular separation, the stroma regained original reflectivity, and multiple hyper-reflective foci (likely fragments from the cuticular-stromal interface) were noted within the SCS. The cornea was relatively unchanged in character or thickness throughout all stages of ecdysis. Slit-lamp images did not permit observation of these changes. Spectral domain optical coherence tomography (SD-OCT) provided excellent high-resolution images of the snake anterior segment, and especially the cuticle, spectacle, and cornea of manually restrained normal snakes at all stages of ecdysis and warrants investigation in snakes with anterior segment disease. The peripheral spectacle may be the preferred entry point for diagnostic or therapeutic injections into the SSS and for initiating spectacular surgery. © 2014 American College of Veterinary Ophthalmologists.

  4. Clay characterization of Boa Saude-RN, Brazil

    International Nuclear Information System (INIS)

    Ren, D.G.; Alencar, M.I.; Ferreira, O.F.; Cunha, J.M.R.; Harima, E.

    2011-01-01

    This study characterized a sample of clay from the City of Boa Saude of Rio Grande do Norte. Clay is burning clear and used in Monte Alegre in the brick kilns for producing bricks and tiles. This study also verified the possibility of using these in the field of industrial ceramics. The following techniques were used for characterization: chemical and mineralogical analysis, which determined the presence of the following minerals, muscovite, quartz and kaolinite, the plasticity index can be said that the clay has an average plasticity index, also was made organic matter content, residue content, determination of loss on ignition was found that a loss of 9.38%, checking the color of burning gave a gradient of cream to orange with increasing temperature. (author)

  5. Image quality of a Konica Regius 336 digital system in chest radiography; Qualita' dell'immagine di un sistema digitale Konica Regius 336 per radiologia toracica

    Energy Technology Data Exchange (ETDEWEB)

    Ostinelli, A.; Frigerio, M.; Monti, A.F.; Gelosa, S.; Tognoli, P.; Perniola, N. [Azienda Ospedaliera S. Anna, Como (Italy). Servizio di Fisica Sanitaria; Gozzi, G. [Azienda Ospedaliera S. Anna, Como (Italy). Servizio di Radiologia

    2000-06-01

    Digital radiographic systems permit to optimize execution, depiction and storage of radiological images. Since a Regius 336 digital system (Konica Corp. Tokyo, Japan) devoted to chest radiography Department of S. Anna Hospital in Como, Italy, it was investigated its performance relative to image quality. Konica Regius 336 is a computed radiography system made of a phosphorescence detector plate which is scanned with an infrared semiconductor laser beam. The radiographic image obtained from the detector is subjected to image processing, which allows a stable output and the nonlinear curve typical of conventional radiographic systems. Image quality was assessed based on the following parameters: dose, contrast, noise and spatial resolution. As reference, it was assessed the same parameters on a Cronex 88 analogic chest-changer (DuPont Pharma, North Billerica, Mass, USA). The Regius 336 air kerma values were always higher than the analogic ones (about 10%), both with and without a chest phantom; noise was also greater than in analogic images, sometimes even doubled. The optical densities of a step wedge and the spatial resolution of the digital chest-changer are independent of the X-ray tube voltage consequent to broader optical latitude. Inversely, the analogic images of the wedges show great optical density variability as a function of the X-ray tube voltage (in a range of 2). The modulation transfer functions of the two systems have the same trend. The performance of the Konica Regius 336 is nearly equivalent to that of an analogic system. The main advantages of the digital system are a standard output, lower consumption of radiographic films, higher productiveness and better image quality standard level. [Italian] I sistemi radiografici digitali offrono la possibilita' di ottimizzare l'esecuzione, la visualizzazione e l'archiviazione dell'immagine radiologica. Poiche' presso il Servizio di Radiologia dell'Azienda Ospedaliera S. Anna

  6. Columbia University's Franz Boas: He Led the Undoing of Scientific Racism.

    Science.gov (United States)

    Baker, Lee D.

    1999-01-01

    As early as 1887, the anthropologist Franz Boas began to combat scientific racism and the insistence that blacks were of lower intelligence than whites. Throughout his career, Boas guided anthropology to a consensus that people of color were not racially inferior and that they possessed unique and historically specific cultures. (SLD)

  7. Spatial Ecology of Puerto Rican Boas (Epicrates inornatus) in a Hurricane Impacted Forest.

    Science.gov (United States)

    Joseph M. Wunderle Jr.; Javier E. Mercado Bernard Parresol Esteban Terranova 2

    2004-01-01

    Spatial ecology of Puerto Rican boas (Epicrates inornatus, Boidae) was studied with radiotelemetry in a subtropical wet forest recovering from a major hurricane (7–9 yr previous) when Hurricane Georges struck. Different boas were studied during three periods relative to Hurricane Georges: before only; before and after; and after only. Mean daily movement per month...

  8. A volcanological and geochemical investigation of Boa Vistta, Cape Verde Islands

    DEFF Research Database (Denmark)

    Dyhr, Charlotte Thorup; Holm, Paul Martin

    2009-01-01

    Boa Vista, the easternmost island in the Cape Verde archipelago, consists of volcanic products, minor intrusions and a thin partial sedimentary cover. The first 15 age results from 40Ar/39Ar incremental heating analysis of groundmass separates from volcanic and plutonic rocks from Boa Vista are p...

  9. Periurethral constrictor: late results of the treatment of post prostatectomy urinary incontinence

    Directory of Open Access Journals (Sweden)

    Roberto S. Lima

    2011-08-01

    Full Text Available OBJECTIVES: We evaluated retrospectively, the long-term outcome of patients with post-prostatectomy urinary incontinence (PPUI after placement of the Periurethral Constrictor (PUC. MATERIALS AND METHODS: Fifty-six men with severe PPUI were studied, with a mean age of 68.5 years old. Fifty-one men had PPUI due to radical surgery having the device placed around the bulbous urethra, and five individuals with benign prostatic hypertrophy (BPH had placement around the bladder neck. The mean follow-up was 82.2 months. RESULTS: Twenty-two patients (39.28% became continent (0 to 1 pad a day and 34 (60.72% were incontinent. Complications were as follows: urethral erosion in 15 (26.78%; mechanical malfunction in 2 (3.5%; infection in 2 (3.5%; urinary fistula in 1 (1.7%; Urinary tract infection1 (1.7%. Twenty-three patients needed to have the device removed (41.07%. Success rate (continent me was 30.35%. CONCLUSION: In the present series the PUC was not effective for the treatment of severe PPUI in the long-term follow-up.

  10. Effect of two different protein/fat ratios of the diet on meagre (Argyrosomus regius traits

    Directory of Open Access Journals (Sweden)

    Giuseppe Moniello

    2010-01-01

    Full Text Available The aim of this study was to evaluate the effect of two diets with different protein/fat ratios (P/F (diet A: P/F 2.26; diet B: P/F 3.36 on the chemical composition, fatty acid profile and some somatic indexes of meagre (Argyrosomus regius. The trial was carried out on two groups of meagre raised in two different sea cages during 15 months. At the end of the production cycle biometric measures as well as chemical-nutritional analysis of the fillets were conducted on 25 fishes per group. Diet A, with a lower P/F, furnished animals with higher percentages of mesenteric fat (0.48 vs 0.41%; P<0.01 and of fillet yield (51.21 vs 48.12; P<0.01. Moreover, the fillets obtained with the diet A showed higher percentage of fat (3.60 vs 2.41%; P< 0.01, lower moisture (74.10 vs 75.42%; P<0.01, lower losses of water under pressure (16.73 vs 20.20%; P<0.01 and after 48 h of refrigeration (3.08 vs 4.23%; P<0.01. The fatty acids profile of fillets was affected by the diet. Diet A resulted in a higher level of saturated fatty acids (26.44 vs 23.17% of total lipid; P<0.01 and a lower percentage of polyunsaturated fatty acids (31.56 vs 36.08%; P<0.01 in the fillet, mainly due to the lower content of linoleic acid (13.63 vs 19.77%; P<0.01. The atherogenic (AI and thrombogenic (TI indexes, which resulted very low in the fish of Group B (AI=0.48 vs 0.60, P<0.01; TI=0.33 vs 0.37, P<0.01, together with the low lipid content of meat in both groups, confirmed the very high nutritional quality of meagre fillets.

  11. Ball python nidovirus: a candidate etiologic agent for severe respiratory disease in Python regius.

    Science.gov (United States)

    Stenglein, Mark D; Jacobson, Elliott R; Wozniak, Edward J; Wellehan, James F X; Kincaid, Anne; Gordon, Marcus; Porter, Brian F; Baumgartner, Wes; Stahl, Scott; Kelley, Karen; Towner, Jonathan S; DeRisi, Joseph L

    2014-09-09

    A severe, sometimes fatal respiratory disease has been observed in captive ball pythons (Python regius) since the late 1990s. In order to better understand this disease and its etiology, we collected case and control samples and performed pathological and diagnostic analyses. Electron micrographs revealed filamentous virus-like particles in lung epithelial cells of sick animals. Diagnostic testing for known pathogens did not identify an etiologic agent, so unbiased metagenomic sequencing was performed. Abundant nidovirus-like sequences were identified in cases and were used to assemble the genome of a previously unknown virus in the order Nidovirales. The nidoviruses, which were not previously known to infect nonavian reptiles, are a diverse order that includes important human and veterinary pathogens. The presence of the viral RNA was confirmed in all diseased animals (n = 8) but was not detected in healthy pythons or other snakes (n = 57). Viral RNA levels were generally highest in the lung and other respiratory tract tissues. The 33.5-kb viral genome is the largest RNA genome yet described and shares canonical characteristics with other nidovirus genomes, although several features distinguish this from related viruses. This virus, which we named ball python nidovirus (BPNV), will likely establish a new genus in Torovirinae subfamily. The identification of a novel nidovirus in reptiles contributes to our understanding of the biology and evolution of related viruses, and its association with lung disease in pythons is a promising step toward elucidating an etiology for this long-standing veterinary disease. Ball pythons are popular pets because of their diverse coloration, generally nonaggressive behavior, and relatively small size. Since the 1990s, veterinarians have been aware of an infectious respiratory disease of unknown cause in ball pythons that can be fatal. We used unbiased shotgun sequencing to discover a novel virus in the order Nidovirales that was

  12. The effects of UV light on calcium metabolism in ball pythons (Python regius).

    Science.gov (United States)

    Hedley, J; Eatwell, K

    2013-10-12

    Despite the popularity of keeping snakes in captivity, there has been limited investigation into the effects of UV radiation on vitamin D levels in snakes. The aim of this study was to investigate the effects of UV-b radiation on plasma 25-hydroxyvitamin D3 levels and ionised calcium concentrations in ball pythons (Python regius). Blood samples were taken from 14 ball pythons, which had never been exposed to UV-b light, to obtain baseline 25-hydroxyvitamin D3 levels and ionised calcium concentrations. Blood samples were then taken again from the same snakes 70 days later after one group (Group 1, n=6 females) were exposed to UV-b radiation daily, and the other group (Group 2, n=5 males and 3 females) were exposed to no UV-b radiation. Mean±sd 25-hydroxyvitamin D3 levels on day 0 in Group 1 were 197±35 nmol/l, and on day 70 were 203.5±13.8 nmol/l. Mean±sd 25-hydroxyvitamin D3 levels in Group 2 on day 0 were 77.7±41.5 nmol/l, and on day 70 were 83.0±41.9 nmol/l. Mean±sd ionised calcium levels at day 0 were 1.84±0.05 mmol/l for Group 1, and on day 70 were 1.78±0.07 mmol/l. Mean±sd ionised calcium levels at day 0 were 1.79±0.07 mmol/l for Group 2, and on day 70 were 1.81±0.05 mmol/l. No association was demonstrated between exposure to UV-b radiation and plasma 25-hydroxyvitamin D3 and ionised calcium concentrations. These results may provide baseline parameters for future studies in this and other snake species to determine ability to utilise UV-b light for vitamin D production.

  13. Hearing with an atympanic ear: good vibration and poor sound-pressure detection in the royal python, Python regius

    DEFF Research Database (Denmark)

    Christensen, Christian Bech; Christensen-Dalsgaard, Jakob; Brandt, Christian

    2012-01-01

    are sensitive to sound pressure and (2) snakes are sensitive to vibrations, but cannot hear the sound pressure per se. Vibration and sound-pressure sensitivities were quantified by measuring brainstem evoked potentials in 11 royal pythons, Python regius. Vibrograms and audiograms showed greatest sensitivity...... at low frequencies of 80-160 Hz, with sensitivities of -54 dB re. 1 m s(-2) and 78 dB re. 20 μPa, respectively. To investigate whether pythons detect sound pressure or sound-induced head vibrations, we measured the sound-induced head vibrations in three dimensions when snakes were exposed to sound...... pressure at threshold levels. In general, head vibrations induced by threshold-level sound pressure were equal to or greater than those induced by threshold-level vibrations, and therefore sound-pressure sensitivity can be explained by sound-induced head vibration. From this we conclude that pythons...

  14. Identification of a novel nidovirus in an outbreak of fatal respiratory disease in ball pythons (Python regius).

    Science.gov (United States)

    Uccellini, Lorenzo; Ossiboff, Robert J; de Matos, Ricardo E C; Morrisey, James K; Petrosov, Alexandra; Navarrete-Macias, Isamara; Jain, Komal; Hicks, Allison L; Buckles, Elizabeth L; Tokarz, Rafal; McAloose, Denise; Lipkin, Walter Ian

    2014-08-08

    Respiratory infections are important causes of morbidity and mortality in reptiles; however, the causative agents are only infrequently identified. Pneumonia, tracheitis and esophagitis were reported in a collection of ball pythons (Python regius). Eight of 12 snakes had evidence of bacterial pneumonia. High-throughput sequencing of total extracted nucleic acids from lung, esophagus and spleen revealed a novel nidovirus. PCR indicated the presence of viral RNA in lung, trachea, esophagus, liver, and spleen. In situ hybridization confirmed the presence of intracellular, intracytoplasmic viral nucleic acids in the lungs of infected snakes. Phylogenetic analysis based on a 1,136 amino acid segment of the polyprotein suggests that this virus may represent a new species in the subfamily Torovirinae. This report of a novel nidovirus in ball pythons may provide insight into the pathogenesis of respiratory disease in this species and enhances our knowledge of the diversity of nidoviruses.

  15. Molecular systematics and historical biogeography of tree boas (Corallus spp.).

    Science.gov (United States)

    Colston, Timothy J; Grazziotin, Felipe G; Shepard, Donald B; Vitt, Laurie J; Colli, Guarino R; Henderson, Robert W; Blair Hedges, S; Bonatto, Sandro; Zaher, Hussam; Noonan, Brice P; Burbrink, Frank T

    2013-03-01

    Inferring the evolutionary and biogeographic history of taxa occurring in a particular region is one way to determine the processes by which the biodiversity of that region originated. Tree boas of the genus Corallus are an ancient clade and occur throughout Central and South America and the Lesser Antilles, making it an excellent group for investigating Neotropical biogeography. Using sequenced portions of two mitochondrial and three nuclear loci for individuals of all recognized species of Corallus, we infer phylogenetic relationships, present the first molecular analysis of the phylogenetic placement of the enigmatic C. cropanii, develop a time-calibrated phylogeny, and explore the biogeographic history of the genus. We found that Corallus diversified within mainland South America, via over-water dispersals to the Lesser Antilles and Central America, and via the traditionally recognized Panamanian land bridge. Divergence time estimates reject the South American Caribbean-Track as a general biogeographic model for Corallus and implicate a role for events during the Oligocene and Miocene in diversification such as marine incursions and the uplift of the Andes. Our findings also suggest that recognition of the island endemic species, C. grenadensis and C. cookii, is questionable as they are nested within the widely distributed species, C. hortulanus. Our results highlight the importance of using widespread taxa when forming and testing biogeographic hypotheses in complex regions and further illustrate the difficulty of forming broadly applicable hypotheses regarding patterns of diversification in the Neotropical region. Copyright © 2012 Elsevier Inc. All rights reserved.

  16. "Handbook of biomedical optics", edited by David A. Boas, Constantinos Pitris, and Nimmi Ramanujam

    Science.gov (United States)

    2012-01-01

    David A. Boas, Constantinos Pitris, and Nimmi Ramanujam, Eds.: Handbook of Biomedical Optics CRC Press, Taylor and Francis Group, Boca Raton, London, New York, 2011 ISBN: 978-1-4200-9036-9 (Hardback), 787 pages

  17. Correlation between dose to the pharyngeal constrictors and patient quality of life and late dysphagia following chemo-IMRT for head and neck cancer

    Energy Technology Data Exchange (ETDEWEB)

    Bhide, Shreerang A., E-mail: sabhide@yahoo.co [Institute of Cancer Research, London (United Kingdom); Royal Marsden NHS Foundation Trust Hospital, London (United Kingdom); Gulliford, Sarah [Institute of Cancer Research, London (United Kingdom); Kazi, Rehan; El-Hariry, Iman; Newbold, Kate [Royal Marsden NHS Foundation Trust Hospital, London (United Kingdom); Harrington, Kevin J [Institute of Cancer Research, London (United Kingdom); Royal Marsden NHS Foundation Trust Hospital, London (United Kingdom); Nutting, Christopher M [Royal Marsden NHS Foundation Trust Hospital, London (United Kingdom)

    2009-12-15

    Purpose: Aim of this study was to correlate dose to pharyngeal constrictors (PC) with subjective and observer-based assessments of swallowing in patients with head and neck cancer undergoing concomitant chemo-IMRT. Materials and methods: Dose-volume histograms (DVHs) for superior constrictor (SC), middle constrictor (MC) and inferior constrictor (IC) were generated for 37 patients. Mean doses to SC, MC and IC were correlated to objective dysphagia grade (1 year, RTOG scoring) and global, total physical (TP) and most relevant components of the physical section (P6, P8) of the MD Anderson dysphagia inventory (MDADI) which was evaluated post-treatment. Odds ratios of dysphagia (>grade 0), poor global (<3), TP (<32), P6 (<3) and P8 (<3) for patients with mean dose > 60 Gy to SC and IC were calculated. Results: There was no significant correlation between mean dose to PC and any of the analysed MDADI parameters and observer-assessed dysphagia grade. Odds ratio of dysphagia (>grade 0), poor global (<3), TP (<32), P6 (<3) and P8 (<3) for patients with mean dose > 60 Gy to IC and SC were not significantly higher than those for patients receiving <60 Gy. Conclusion: This study did not find a statistically significant correlation between radiation dose to the PC and observer-assessed dysphagia grade or patient-reported MDADI questionnaire at 1 year.

  18. Correlation between dose to the pharyngeal constrictors and patient quality of life and late dysphagia following chemo-IMRT for head and neck cancer

    International Nuclear Information System (INIS)

    Bhide, Shreerang A.; Gulliford, Sarah; Kazi, Rehan; El-Hariry, Iman; Newbold, Kate; Harrington, Kevin J.; Nutting, Christopher M.

    2009-01-01

    Purpose: Aim of this study was to correlate dose to pharyngeal constrictors (PC) with subjective and observer-based assessments of swallowing in patients with head and neck cancer undergoing concomitant chemo-IMRT. Materials and methods: Dose-volume histograms (DVHs) for superior constrictor (SC), middle constrictor (MC) and inferior constrictor (IC) were generated for 37 patients. Mean doses to SC, MC and IC were correlated to objective dysphagia grade (1 year, RTOG scoring) and global, total physical (TP) and most relevant components of the physical section (P6, P8) of the MD Anderson dysphagia inventory (MDADI) which was evaluated post-treatment. Odds ratios of dysphagia (>grade 0), poor global ( 60 Gy to SC and IC were calculated. Results: There was no significant correlation between mean dose to PC and any of the analysed MDADI parameters and observer-assessed dysphagia grade. Odds ratio of dysphagia (>grade 0), poor global ( 60 Gy to IC and SC were not significantly higher than those for patients receiving <60 Gy. Conclusion: This study did not find a statistically significant correlation between radiation dose to the PC and observer-assessed dysphagia grade or patient-reported MDADI questionnaire at 1 year.

  19. Uma "boa" educação A "good" education

    Directory of Open Access Journals (Sweden)

    Monique de Saint Martin

    1999-04-01

    Full Text Available Uma educação ética 3/4 uma "boa" educação 3/4 de sua filhas sempre representou uma preocupação central para as camadas dominantes da burguesia e da aristocracia. A instrução, por outro lado, por visar essencialmente atividades intelectuais, sempre foi vista como secundária, assim como, no caso dessas moças, a transmissão do capital cultural e econômico. Mais do que uma exceção, a escola "Notre-Dame des Oiseaux" representa um caso-limite. Com algumas concessões à nova moralidade burguesa e na base de uma homogeneidade consistente, não apenas das alunas como das docentes e freiras, a educação das moças desse meio continua centrada no preparo para um papel específico - o de mãe "feliz", esposa culta, com um emprego (embora disposta a abandoná-lo, pia e envolvida em ações caridosas.For the dominant sections of the bourgeoisie and the aristocracy, an ethical education 3/4 a "good"education 3/4 for their daughters, is always a major preoccupation.Instruction, on the other hand, a training for intellectual activity, is considered of secundary importance, as though, in the case of theses girls, the transmission of the economic and cultural capital. The "Notre Dame des Oiseaux" school, is not so much an excepcional case as a bordeline case.With a few concessions to the new bourgeois morality, and thanks to the extreme homogeneity not only of its pupils, but also of its teaching staff and the sisters, the preparation for a specific role 3/4 "happy" mother, cultivated wife, with a job but quite prepared to give it up, pious, involved in some charitable activity 3/4 remains the most important aspect of the education of young girls of this milieu.

  20. Tachycardia in response to remote capsaicin injection as a model for nociception in the ball python (Python regius).

    Science.gov (United States)

    Williams, Catherine J A; James, Lauren E; Bertelsen, Mads F; Wang, Tobias

    2016-07-01

    To quantify the effect of subcutaneous (SC) capsaicin injection on heart rate (HR) in ball pythons (Python regius) and to assess the efficacy of two opioids (morphine and butorphanol) in modifying this response. Prospective, randomized, unmatched study. Eleven mixed-sex, captive-bred ball pythons. Snakes were randomly assigned to three groups (n = 6) by intramuscular premedication: 1) control: saline (0.9 mL); 2) morphine (10 mg kg(-1) ); and 3) butorphanol (10 mg kg(-1) ). Three snakes were tested twice and another two were tested three times in different treatments administered 1 month apart. Under isoflurane anaesthesia, snakes were instrumented with SC electrocardiogram (ECG) electrodes and an SC catheter for remote stimulus delivery. After recovery from anaesthesia, all snakes, in visual and audial isolation from the experimenter, received a sham stimulus of saline (0.4 mL) via the SC catheter. A nociceptive stimulus of SC capsaicin (3 mg in 0.2 mL saline with 7% Tween 80) was then applied by catheter at 7 hours after premedication. In a subset (n = 3), two sham injections (saline 0.2 mL) preceded the capsaicin treatment. HR was recorded via ECG, and changes in HR (ΔHR) from baseline were calculated for all stimulations. Capsaicin injection was associated with a significant increase in HR [peak ΔHR: saline group: 8.8 ± 7.1 beats minute(-1) ; capsaicin group: 21.1 ± 5.8 beats minute(-1) (p = 0.0055)] and integrated ΔHR as a function of time. The administration of morphine or butorphanol 7 hours prior to nociception failed to significantly reduce the peak and integrated ΔHR. Butorphanol caused marked, long-lasting sedation as assessed by muscle tone. The HR response to an SC capsaicin injection can serve as a nociceptive model in P. regius. Morphine and butorphanol administration did not reduce HR response to capsaicin stimulation but produced significantly different effects on pre-stimulation HR and sedation. © 2015 Association

  1. Phylogeographic and population genetic analyses reveal multiple species of Boa and independent origins of insular dwarfism.

    Science.gov (United States)

    Card, Daren C; Schield, Drew R; Adams, Richard H; Corbin, Andrew B; Perry, Blair W; Andrew, Audra L; Pasquesi, Giulia I M; Smith, Eric N; Jezkova, Tereza; Boback, Scott M; Booth, Warren; Castoe, Todd A

    2016-09-01

    Boa is a Neotropical genus of snakes historically recognized as monotypic despite its expansive distribution. The distinct morphological traits and color patterns exhibited by these snakes, together with the wide diversity of ecosystems they inhabit, collectively suggest that the genus may represent multiple species. Morphological variation within Boa also includes instances of dwarfism observed in multiple offshore island populations. Despite this substantial diversity, the systematics of the genus Boa has received little attention until very recently. In this study we examined the genetic structure and phylogenetic relationships of Boa populations using mitochondrial sequences and genome-wide SNP data obtained from RADseq. We analyzed these data at multiple geographic scales using a combination of phylogenetic inference (including coalescent-based species delimitation) and population genetic analyses. We identified extensive population structure across the range of the genus Boa and multiple lines of evidence for three widely-distributed clades roughly corresponding with the three primary land masses of the Western Hemisphere. We also find both mitochondrial and nuclear support for independent origins and parallel evolution of dwarfism on offshore island clusters in Belize and Cayos Cochinos Menor, Honduras. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Tribological analysis of the ventral scale structure in a Python regius in relation to laser textured surfaces

    International Nuclear Information System (INIS)

    Abdel-Aal, H A; El Mansori, M

    2013-01-01

    Laser texturing is one of the leading technologies applied to modify surface topography. To date, however, a standardized procedure to generate deterministic textures is virtually non-existent. In nature, especially in squamata, there are many examples of deterministic structured textures that allow species to control friction and condition their tribological response for efficient function. In this work, we draw a comparison between industrial surfaces and reptilian surfaces. We chose the Python regius species as a bio-analogue with a deterministic surface. We first study the structural make up of the ventral scales of the snake (both construction and metrology). We further compare the metrological features of the ventral scales to experimentally recommended performance indicators of industrial surfaces extracted from open literature. The results indicate the feasibility of engineering a laser textured surface based on the reptilian ornamentation constructs. It is shown that the metrological features, key to efficient function of a rubbing deterministic surface, are already optimized in the reptile. We further show that optimization in reptilian surfaces is based on synchronizing surface form, textures and aspects to condition the frictional response. Mimicking reptilian surfaces, we argue, may form a design methodology potentially capable of generating advanced deterministic surface constructs capable of efficient tribological function. (paper)

  3. Reproductive phase determination in male meagre (Argyrosomus regius, Sciaenidae: testis development and histologic corroboration of a gross anatomical scale

    Directory of Open Access Journals (Sweden)

    Nuno Prista

    2014-03-01

    Full Text Available Reproductive stage determination of male gonads has received sparse attention in fish biology literature with few studies detailing the building of gross anatomical- and histologic scales. The meagre (Argyrosomus regius is one of the world’s largest sciaenids and supports a significant regional fishery in European and North African waters whose reproductive patterns are yet to be fully investigated. In the present study, we derive a macroscopic grading system for meagre testis using semi-quantitative graphs that feature the testis variability along the species size range and time of the year. We then describe the histological stages and reproductive phases of male testes and determine the extent to which they corroborate the anatomical scale. Our results indicate that gross anatomical analyses are accurate in assessments of the meagre spawning season but may not precisely distinguish the testes of well-mature fish and first spawning virgins. Furthermore, we show that milt expression varies widely with size and misclassifies as immature many smaller fish in spawning-capable condition. We discuss these findings in terms of their contribution to the understanding of testes development and the uncertainties involved in determining the size-at-maturity of male fish using gross anatomical scales.

  4. Clinical and histologic effects of intracardiac administration of propofol for induction of anesthesia in ball pythons (Python regius).

    Science.gov (United States)

    McFadden, Michael S; Bennett, R Avery; Reavill, Drury R; Ragetly, Guillaume R; Clark-Price, Stuart C

    2011-09-15

    To assess the clinical differences between induction of anesthesia in ball pythons with intracardiac administration of propofol and induction with isoflurane in oxygen and to assess the histologic findings over time in hearts following intracardiac administration of propofol. Prospective randomized study. 30 hatchling ball pythons (Python regius). Anesthesia was induced with intracardiac administration of propofol (10 mg/kg [4.5 mg/lb]) in 18 ball pythons and with 5% isoflurane in oxygen in 12 ball pythons. Induction time, time of anesthesia, and recovery time were recorded. Hearts from snakes receiving intracardiac administration of propofol were evaluated histologically 3, 7, 14, 30, and 60 days following propofol administration. Induction time with intracardiac administration of propofol was significantly shorter than induction time with 5% isoflurane in oxygen. No significant differences were found in total anesthesia time. Recovery following intracardiac administration of propofol was significantly longer than recovery following induction of anesthesia with isoflurane in oxygen. Heart tissue evaluated histologically at 3, 7, and 14 days following intracardiac administration of propofol had mild inflammatory changes, and no histopathologic lesions were seen 30 and 60 days following propofol administration. Intracardiac injection of propofol in snakes is safe and provides a rapid induction of anesthesia but leads to prolonged recovery, compared with that following induction with isoflurane. Histopathologic lesions in heart tissues following intracardiac injection of propofol were mild and resolved after 14 days.

  5. Development of a technique for contrast radiographic examination of the gastrointestinal tract in ball pythons (Python regius).

    Science.gov (United States)

    Banzato, Tommaso; Russo, Elisa; Finotti, Luca; Zotti, Alessandro

    2012-07-01

    To develop a technique for radiographic evaluation of the gastrointestinal tract in ball pythons (Python regius). 10 ball python cadavers (5 males and 5 females) and 18 healthy adult ball pythons (10 males and 8 females). Live snakes were allocated to 3 groups (A, B, and C). A dose (25 mL/kg) of barium sulfate suspension at 3 concentrations (25%, 35%, and 45% [wt/vol]) was administered through an esophageal probe to snakes in groups A, B, and C, respectively. Each evaluation ended when all the contrast medium had reached the large intestine. Transit times through the esophagus, stomach, and small intestine were recorded. Imaging quality was evaluated by 3 investigators who assigned a grading score on the basis of predetermined criteria. Statistical analysis was conducted to evaluate differences in quality among the study groups. The esophagus and stomach had a consistent distribution pattern of contrast medium, whereas 3 distribution patterns of contrast medium were identified in the small intestine, regardless of barium concentration. Significant differences in imaging quality were detected among the 3 groups. Radiographic procedures were tolerated well by all snakes. The 35% concentration of contrast medium yielded the best imaging quality. Use of contrast medium for evaluation of the cranial portion of the gastrointestinal tract could be a reliable technique for the diagnosis of gastrointestinal diseases in ball pythons. However, results of this study may not translate to other snake species because of variables identified in this group of snakes.

  6. Pharmacokinetics of a long-acting ceftiofur formulation (ceftiofur crystalline free acid) in the ball python (Python regius).

    Science.gov (United States)

    Adkesson, Michael J; Fernandez-Varon, Emilio; Cox, Sherry; Martín-Jiménez, Tomás

    2011-09-01

    The objective of this study was to determine the pharmacokinetics of a long-acting formulation of ceftiofur crystalline-free acid (CCFA) following intramuscular injection in ball pythons (Python regius). Six adult ball pythons received an injection of CCFA (15 mg/kg) in the epaxial muscles. Blood samples were collected by cardiocentesis immediately prior to and at 0.5, 1, 2, 4, 8, 12, 18, 24, 48, 72, 96, 144, 192, 240, 288, 384, 480, 576, 720, and 864 hr after CCFA administration. Plasma ceftiofur concentrations were determined by high-performance liquid chromatography. A noncompartmental pharmacokinetic analysis was applied to the data. Maximum plasma concentration (Cmax) was 7.096 +/- 1.95 microg/ml and occurred at (Tmax) 2.17 +/- 0.98 hr. The area under the curve (0 to infinity) for ceftiofur was 74.59 +/- 13.05 microg x h/ml and the elimination half-life associated with the terminal slope of the concentration-time curve was 64.31 +/- 14.2 hr. Mean residence time (0 to infinity) was 46.85 +/- 13.53 hr. CCFA at 15 mg/kg was well tolerated in all the pythons. Minimum inhibitory concentration (MIC) data for bacterial isolates from snakes are not well established. For MIC values of python. For MICs > or =0.5 microg/ml, more frequent dosing or a higher dosage may be required.

  7. Meagre Argyrosomus regius (Osteichthyes) as host of a gonad-infecting species of Philometra (Nematoda: Philometridae) off the Atlantic coast of Portugal

    Czech Academy of Sciences Publication Activity Database

    Moravec, František; Prista, N.; Costa, M. J.

    2007-01-01

    Roč. 78, č. 1 (2007), s. 83-86 ISSN 0177-5103 R&D Projects: GA ČR(CZ) GA524/06/0170; GA MŠk LC522 Grant - others: Portuguese Fisheries Directorate(PT) CORV22-05-01-FDR-00036; Portuguese Science and Technology Foundation(PT) BD12550/2003 Institutional research plan: CEZ:AV0Z60220518 Keywords : Philometra * marine fish * Portugal * parasitic nematode * fish gonad * Argyrosomus regius Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 1.598, year: 2007

  8. Utilização de Placas de polipropileno e fios de náilon na técnica de fixação espinhal segmentar modificada em uma jibóia Polypropylene plates and nylon suture in a modified technique of segmental spinal fixation in a redtail boa

    Directory of Open Access Journals (Sweden)

    Simone Borges Salgueiro De Simone

    2011-05-01

    Full Text Available Um exemplar adulto de Boa constrictor com histórico de atropelamento foi atendido no Hospital Veterinário. Exames clínico e radiográfico identificaram a presença de uma luxação no terço médio da coluna vertebral. O paciente foi submetido à estabilização cirúrgica da lesão, em que se avaliou a eficácia de uma variação da técnica de fixação espinhal segmentar modificada. O segmento foi estabilizado através da fixação e placas plásticas sob forma de hemicerclagem nos corpos vertebrais, com auxílio de fio de náilon n. 0 e a síntese tecidual finalizou o procedimento. No pós-operatório, instituiu-se a antibioticoterapia, curativos locais diários e restrição de espaço até a cicatrização total do ferimento. A variação da técnica mostrou ser eficaz no realinhamento e estabilização anatômica da luxação do segmento vertebral para a serpente em questão.An adult exemplar of Boa constrictor with a history of overthrowing was send to the Veterinary Hospital. Clinical and radiographic examinations identified the presence of a dislocation in the third middle of the spine. The patient was submitted to a surgical correction of the lesion, which evaluated the effectiveness of a variation of the modified technique of segmental spinal fixation. The segment was stabilized by fixing plastic plates in the form of hemicerclage in the vertebral bodies, with nylon n.0, and tissue synthesis completed the procedure. Postoperatively, it was instituted antibiotic therapy, daily curatives and space restrictions until the complete healing of the wound. The variation of the technique has proved to be safe and effective for the snake of this study, promoting the realignment and stabilization of the anatomical vertebral segment.

  9. 75 FR 13264 - Meeting of the Board of Advisors (BOA) to the President, Naval Postgraduate School (NPS)

    Science.gov (United States)

    2010-03-19

    ... DEPARTMENT OF DEFENSE Department of the Navy Meeting of the Board of Advisors (BOA) to the President, Naval Postgraduate School (NPS) AGENCY: Department of the Navy, DoD. ACTION: Notice of open... access, information, or to send written comments regarding the NPS BOA, contact Ms. Jaye Panza, Naval...

  10. Preliminary Assessment of Road Mortality in Chilabothrus exsul, the Northern Bahamas Boa.

    NARCIS (Netherlands)

    Reynolds, R. Graham; Giery, Sean T.; Jesse, W.A.M.; Quach, Quynh H.

    2016-01-01

    The Northern Bahamas Boa (Chilabothrus exsul) is a secretive species of boid snake that occupies a relatively small range on the Northern Bahamas Bank. Little is known regarding the natural history of this species or its conservation status. As a component of conducting an IUCN Red List Assessment

  11. MIGRAÇÕES E MÚLTIPLAS TERRITORIALIDADES DOS IMIGRANTES EM BOA VISTA-RR

    Directory of Open Access Journals (Sweden)

    Pedro Marcelo Staevie

    2012-01-01

    Full Text Available The present article aims to show the migratory process towards the Boa Vista city and the multiple existing territorialities in the urban space of the city. W ith a population formed by immigrants, mostly northeasters, the capital of Roraima is configured in a multifaceted city, a place of distinct territorial manifestations.

  12. Anaesthetic induction with alfaxalone in the ball python (Python regius): dose response and effect of injection site.

    Science.gov (United States)

    James, Lauren E; Williams, Catherine Ja; Bertelsen, Mads F; Wang, Tobias

    2018-05-01

    To characterise the minimum dose of intramuscular alfaxalone required to facilitate intubation for mechanical ventilation, and to investigate the impact of cranial versus caudal injection on anaesthetic depth. Randomised crossover study. Six healthy juvenile ball pythons (Python regius). Three dosages (10, 20 and 30 mg kg -1 ) of alfaxalone were administered to each python in a caudal location with a minimum 2 weeks washout. Induction and recovery were monitored by assessing muscle tone, righting reflex, response to a noxious stimulus and the ability to intubate. A subsequent experiment assessed the influence of injection site by comparing administration of 20 mg kg -1 alfaxalone in a cranial location (1 cm cranial to the heart) with the caudal site. Respiration rate was monitored throughout, and when intubation was possible, snakes were mechanically ventilated. Regardless of dose and injection site, maximum effect was reached within 10.0 ± 2.7 minutes. When administered at the caudal injection site, intubation was only successful after a dosage of 30 mg kg- 1 , which is higher than in previous reports for other reptiles. However, intubation was possible in all cases after 7.2 ± 1.6 minutes upon cranial administration of 20 mg kg -1 , and anaesthetic duration was significantly lengthened (p pythons, and may serve as a useful induction agent prior to provision of volatile anaesthetics. The same dosage injected in the cranial site led to deeper anaesthesia than when injected caudally, suggesting that shunting to the liver and first-pass metabolism of alfaxalone occur when injected caudally, via the renal portal system. Copyright © 2018 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.

  13. Photodermatitis and photokeratoconjunctivitis in a ball python (Python regius) and a blue-tongue skink (Tiliqua spp.).

    Science.gov (United States)

    Gardiner, David W; Baines, Frances M; Pandher, Karamjeet

    2009-12-01

    A male ball python (Python regius) and a female blue tongue skink (Tiliqua spp.) of unknown age were evaluated for anorexia, lethargy, excessive shedding, corneal opacity (python), and weight loss (skink) of approximately three weeks' duration. These animals represented the worst affected animals from a private herpetarium where many animals exhibited similar signs. At necropsy, the python had bilateral corneal opacity and scattered moderate dysecdysis. The skink had mild dysecdysis, poor body condition, moderate intestinal nematodiasis, and mild liver atrophy. Microscopic evaluation revealed epidermal erosion and ulceration, with severe epidermal basal cell degeneration and necrosis, and superficial dermatitis (python and skink). Severe bilateral ulcerative keratoconjunctivitis with bacterial colonization was noted in the ball python. Microscopic findings within the skin and eyes were suggestive of ultraviolet (UV) radiation damage or of photodermatitis and photokeratoconjunctivitis. Removal of the recently installed new lamps from the terrariums of the surviving reptiles resulted in resolution of clinical signs. Evaluation of a sample lamp of the type associated with these cases revealed an extremely high UV output, including very-short-wavelength UVB, neither found in natural sunlight nor emitted by several other UVB lamps unassociated with photokeratoconjunctivitis. Exposure to high-intensity and/or inappropriate wavelengths of UV radiation may be associated with significant morbidity, and even mortality, in reptiles. Veterinarians who are presented with reptiles with ocular and/or cutaneous disease of unapparent cause should fully evaluate the specifics of the vivarium light sources. Further research is needed to determine the characteristics of appropriate and of toxic UV light for reptiles kept in captivity.

  14. Hearing with an atympanic ear: good vibration and poor sound-pressure detection in the royal python, Python regius.

    Science.gov (United States)

    Christensen, Christian Bech; Christensen-Dalsgaard, Jakob; Brandt, Christian; Madsen, Peter Teglberg

    2012-01-15

    Snakes lack both an outer ear and a tympanic middle ear, which in most tetrapods provide impedance matching between the air and inner ear fluids and hence improve pressure hearing in air. Snakes would therefore be expected to have very poor pressure hearing and generally be insensitive to airborne sound, whereas the connection of the middle ear bone to the jaw bones in snakes should confer acute sensitivity to substrate vibrations. Some studies have nevertheless claimed that snakes are quite sensitive to both vibration and sound pressure. Here we test the two hypotheses that: (1) snakes are sensitive to sound pressure and (2) snakes are sensitive to vibrations, but cannot hear the sound pressure per se. Vibration and sound-pressure sensitivities were quantified by measuring brainstem evoked potentials in 11 royal pythons, Python regius. Vibrograms and audiograms showed greatest sensitivity at low frequencies of 80-160 Hz, with sensitivities of -54 dB re. 1 m s(-2) and 78 dB re. 20 μPa, respectively. To investigate whether pythons detect sound pressure or sound-induced head vibrations, we measured the sound-induced head vibrations in three dimensions when snakes were exposed to sound pressure at threshold levels. In general, head vibrations induced by threshold-level sound pressure were equal to or greater than those induced by threshold-level vibrations, and therefore sound-pressure sensitivity can be explained by sound-induced head vibration. From this we conclude that pythons, and possibly all snakes, lost effective pressure hearing with the complete reduction of a functional outer and middle ear, but have an acute vibration sensitivity that may be used for communication and detection of predators and prey.

  15. Agronomic performance of watermelon cultivars in the Cerrado region of Boa Vista, Roraima = Desempenho agronômico de cultivares de melancia no cerrado de Boa Vista, Roraima

    Directory of Open Access Journals (Sweden)

    Ignácio Lund Gabriel da Silva Carmo

    2015-10-01

    Full Text Available Production of the watermelon is important in all regions of Brazil. However, productive and qualitative information for fruit of different cultivars grown in the same environment is still scarce, especially in the State of Roraima, a fact that makes it necessary to carry out studies in order to meet this need. As a result, this study aimed to evaluate the agronomic performance of watermelon cultivars produced in the Cerrado at Boa Vista, Roraima. The experiment was conducted at the Agua Boa Experimental Farm of Embrapa Roraima, from December 2013 to February 2014. The experimental design was of randomised blocks (DBC, with six replications. The treatments comprised six watermelon cultivars: Verena, Explore, Elisa, Juliane, Crimson Sweet and Crimson Sweet Super, for which the productive, physical, chemical and physicochemical characteristics of the fruit were evaluated. There was no difference between cultivars in yield, number of fruit ha-1 or the number of fruit with a weight of between 6 and 9 kg. The cultivars differed as to physical characteristics (weight, size and number of seeds per fruit. There were differences between cultivars for all the chemical and physicochemical characteristics of the fruit. The cultivar Elisa displayed the highest levels for total soluble solids (12.58 °Brix. Fruits of the cultivars Explore and Crimson Sweet Super showed the greatest ratio between total soluble solids and titratable acidity. The fruits of the cultivars Explore and Elisa had the highest pH. The conditions of soil and climate in the Cerrado at Boa Vista favour the productive and qualitative characteristics of the cultivars being analysed. = A produção de melancia é consolidada em todas as regiões do Brasil. Porém, as informações sobre produtividade e qualidade dos frutos, de diferentes cultivares no mesmo ambiente, ainda são tímidas, sobretudo em Roraima, tornando necessária a realização de estudos para suprir essa carência. Objetivou

  16. Neutron imaging options at the BOA beamline at Paul Scherrer Institut

    International Nuclear Information System (INIS)

    Morgano, M.; Peetermans, S.; Lehmann, E.H.; Panzner, T.; Filges, U.

    2014-01-01

    The BOA beamline at the Swiss spallation neutron source SINQ at Paul Scherrer Institut is a flexible instrument used mainly for testing novel techniques and devices for neutron scattering and optics, but, due to the large and relatively homogeneous field of view, it can be successfully used for experiments in the field of neutron imaging. The beamline allows also for the exploitation of advanced imaging concepts such as polarized neutron imaging and diffractive neutron imaging. In this paper we present the characterization of the BOA beamline in the light of its neutron imaging capabilities. We show also the different techniques that can be employed there as user-friendly plugins for non-standard neutron imaging experiments

  17. Habitat association, size, stomach contents, and reproductive condition of Puerto Rican boas (Epicrates inornatus)

    Science.gov (United States)

    Wiley, J.W.

    2003-01-01

    The Puerto Rican boa occurs in a variety of habitats, including wet montane forest, lowland wet forest, mangrove forest, wet limestone karst, and offshore cays, and from sea level to 480 m. Mean SVL of 49 encountered boas (live and road-killed) was 136.9 ?? 35.1 (range = 38.8-205 cm), with a mean mass of 952.1 ?? 349.0 g (n = 47; range = 140-1662 g). Prey in digestive tracts (n = 29) included remains of black rats, house mice, three species of anoles, bats, common ground-doves, domestic fowl chicks, and invertebrates. Females were in reproductive condition in late April through mid-August and had an average brood size of 21.8 ?? 6.0 (n = 9, range = 13-30 ).

  18. BOA II: Asbestos Pipe-Insulation Removal Robot System. Innovative Technology Summary Report

    International Nuclear Information System (INIS)

    None

    2001-01-01

    The objective of this task is to develop and demonstrate a mechanical, asbestos-removal system that can be remotely operated without a containment area. The technology, known as BOA, consists of a pipe-crawler removal head and a boom vehicle system with dual robots. BOA's removal head can be remotely placed on the outside of the pipe and can crawl along the pipe, removing lagging and insulation. The lagging and insulation is cut using a hybrid endmill water-jet cutter and then diced into 2-inch cube sections of ACM. These ACM sections are then removed from the pipe using a set of blasting fan- spray nozzles, vacuumed off through a vacuum hose, and bagged. Careful attention to vacuum and entrapment air flow ensures that the system can operate without a containment area while meeting local and federal standards for fiber count

  19. BOA: Asbestos pipe-insulation removal robot system. Phase I. Topical report, November 1993--December 1994

    International Nuclear Information System (INIS)

    Schempf, H.; Bares, J.E.

    1995-01-01

    Based on several key design criteria and site visits, we developed a Robot design and built a system which automatically strips the lagging and insulation from the pipes, and encapsulates them under complete vacuum operation. The system can operate on straight runs of piping in horizontal or vertical orientations. Currently we are limited to four-inch diameter piping without obstacles as well as a somewhat laborious emplacement and removal procedure. Experimental results indicated that the current robotic abatement process is sound yet needs to be further expanded and modified. One of the main discoveries was that a longitudinal cut to fully allow the paddles to dig in and compress the insulation off the pipe is essential. Furthermore, a different cutting method might be explored to alleviate the need for a deeper cut and to enable a combination of certain functions such as compression and cutting. Unfortunately due to a damaged mechanism caused by extensive testing, we were unable to perform vertical piping abatement experiments, but foresee no trouble in implementing them in the next proposed Phase. Other encouraging results have BOA removing asbestos at a rate of 4-5 ft./h compared to 3 ft./h for manual removal of asbestos with a 3-person crew. However, we feel confident that we can double the asbestos removal rate by improving cutting speed, and increasing the length of the BOA robot. The containment and vacuum system on BOA is able to achieve the regulatory requirement for airborne fiber emissions of 0.01 fibers/ccm/8-hr. shift. Currently, BOA weighs about 117 pounds which is more than a human is permitted to lift overhead under OSHA requirements (i.e., 25 pounds). We are considering designing the robot into two components (i.e., locomotor section and cutter/removal section) to aid human installation as well as incorporating composite materials. A more detailed list of all the technical modifications is given in this topical report

  20. BOA: Asbestos pipe-insulation removal robot system. Phase I. Topical report, November 1993--December 1994

    Energy Technology Data Exchange (ETDEWEB)

    Schempf, H.; Bares, J.E.

    1995-01-01

    Based on several key design criteria and site visits, we developed a Robot design and built a system which automatically strips the lagging and insulation from the pipes, and encapsulates them under complete vacuum operation. The system can operate on straight runs of piping in horizontal or vertical orientations. Currently we are limited to four-inch diameter piping without obstacles as well as a somewhat laborious emplacement and removal procedure. Experimental results indicated that the current robotic abatement process is sound yet needs to be further expanded and modified. One of the main discoveries was that a longitudinal cut to fully allow the paddles to dig in and compress the insulation off the pipe is essential. Furthermore, a different cutting method might be explored to alleviate the need for a deeper cut and to enable a combination of certain functions such as compression and cutting. Unfortunately due to a damaged mechanism caused by extensive testing, we were unable to perform vertical piping abatement experiments, but foresee no trouble in implementing them in the next proposed Phase. Other encouraging results have BOA removing asbestos at a rate of 4-5 ft./h compared to 3 ft./h for manual removal of asbestos with a 3-person crew. However, we feel confident that we can double the asbestos removal rate by improving cutting speed, and increasing the length of the BOA robot. The containment and vacuum system on BOA is able to achieve the regulatory requirement for airborne fiber emissions of 0.01 fibers/ccm/8-hr. shift. Currently, BOA weighs about 117 pounds which is more than a human is permitted to lift overhead under OSHA requirements (i.e., 25 pounds). We are considering designing the robot into two components (i.e., locomotor section and cutter/removal section) to aid human installation as well as incorporating composite materials. A more detailed list of all the technical modifications is given in this topical report.

  1. Potencial alelopático de 2-benzoxazolinona (boa e sua interação com atrazine no crescimento de plantas Allelopathic potential of 2-benzoxazolinone (boa and its interactions with atrazine on lant growth

    Directory of Open Access Journals (Sweden)

    Itamar F. Souza

    1994-01-01

    Full Text Available Dois experimentos de laboratório foram conduzidos na Universidade de South Dakota, Vemillion, SD, EUA, em 1990, para determinar os efeitos do ácido hidroxâmico benzoxazolinona (BOA, do herbicida atrazine e de suas misturas sobre o crescimento e teor de clorofila de lentilha dágua (Lemna minor. BOA na concentração de 0,5 mM foi aplicado em combinação com atrazine a 0,001 e 0,005 mM em caixas plásticas com 24 células de 2,5 ml, contendo 3 frondes de lentilha dágua em solução nutritiva. BOA e atrazine, aplicados isoladamente, inibiram o número, o peso sêco e o teor de clorofila. Atrazine apresentou uma maior ação inibitória que BOA. A combinação BOA (0,05 mM e atrazine à 0,001 mM foi antagonística. A inibição induzida pelo atrazine a 0,001 mM foi, em parte, neutralizada, porém, com a dose 0,005 mM a sua ação inibitória não foi alterada.Two laboratoy experiments were carried out at the University of South Dakota, Vermillion, SD, USA, in 1990, to determine the effects of hydroxamic acid benzoxazolinone (BOA, the herbicide atrazine, and a mixture there of on duckweed growth and its chlorophyll content. BOA at 0.5 mM concentration was applied in combination with atrazine at 0.001 and 0.005 mM in a 2.5 ml cell tissue cluster dish containing three fronds of duckweed in nutrient solution. Single applications of BOA and atrazine inhibited duckweed frond number, frond dry weight, and its chlorophyll content. Atrazine showed stronger inbibition effect than BOA. The combination BOA and atrazine at 0.001 mM was antagonistic where the inhibition induced by the herbicide was counteracted. Unlike atrazine at 0.00I mM, BOA added to atrazine at 0,005 mM did not counteract the inhibitio caused by the herbicide.

  2. Parallel selective pressures drive convergent diversification of phenotypes in pythons and boas.

    Science.gov (United States)

    Esquerré, Damien; Scott Keogh, J

    2016-07-01

    Pythons and boas are globally distributed and distantly related radiations with remarkable phenotypic and ecological diversity. We tested whether pythons, boas and their relatives have evolved convergent phenotypes when they display similar ecology. We collected geometric morphometric data on head shape for 1073 specimens representing over 80% of species. We show that these two groups display strong and widespread convergence when they occupy equivalent ecological niches and that the history of phenotypic evolution strongly matches the history of ecological diversification, suggesting that both processes are strongly coupled. These results are consistent with replicated adaptive radiation in both groups. We argue that strong selective pressures related to habitat-use have driven this convergence. Pythons and boas provide a new model system for the study of macro-evolutionary patterns of morphological and ecological evolution and they do so at a deeper level of divergence and global scale than any well-established adaptive radiation model systems. © 2016 John Wiley & Sons Ltd/CNRS.

  3. AMS Observations over Coastal California from the Biological and Oceanic Atmospheric Study (BOAS)

    Science.gov (United States)

    Bates, K. H.; Coggon, M. M.; Hodas, N.; Negron, A.; Ortega, A. M.; Crosbie, E.; Sorooshian, A.; Nenes, A.; Flagan, R. C.; Seinfeld, J.

    2015-12-01

    In July 2015, fifteen research flights were conducted on a US Navy Twin Otter aircraft as part of the Biological and Oceanic Atmospheric Study (BOAS) campaign. The flights took place near the California coast at Monterey, to investigate the effects of sea surface temperature and algal blooms on oceanic particulate emissions, the diurnal mixing of urban pollution with other airmasses, and the impacts of biological aerosols on the California atmosphere. The aircraft's payload included an aerosol mass spectrometer (AMS), a differential mobility analyzer, a cloud condensation nuclei counter, a counterflow virtual impactor, a cloudwater collector, and two instruments designed to detect biological aerosols - a wideband integrated biological spectrometer and a SpinCon II - as well as a number of meteorology and aerosol probes, two condensation particle counters, and instruments to measure gas-phase CO, CO2, O3, and NOx. Here, we describe in depth the objectives and outcomes of BOAS and report preliminary results, primarily from the AMS. We detail the spatial characteristics and meteorological variability of speciated aerosol components over a strong and persistent bloom of Pseudo-Nitzschia, the harmful algae that cause 'red tide', and report newly identified AMS markers for biological particles. Finally, we compare these results with data collected during BOAS over urban, forested, and agricultural environments, and describe the mixing observed between oceanic and terrestrial airmasses.

  4. Climatic conditions for grapevine cultivation in Boa Vista, Roraima, Brazil = Aptidão climática para o cultivo da videira em Boa Vista, Roraima

    Directory of Open Access Journals (Sweden)

    Marco Antônio Fonseca Conceição

    2014-12-01

    Full Text Available Grapevine plants have been grown in different tropical regions of Brazil. In the state of Roraima, this culture was introduced commercially in 2005 in Boa Vista. Unlike temperate regions, tropical regions present thermal conditions for grape production throughout the year. To evaluate the climatic characteristics on different periods of the year, it can be used different indices. The objective of this study was to characterize climate suitability of Boa Vista, Roraima, Brazil, for grapevine cultivation at different months of the year. For climate classification it was used the Geoviticulture Multicriteria Climatic Classification System (CCM, which is composed by three indices: Heliothermal (IH, Cool Night (IF, and Drought (IS. It was also used the Zuluaga Index (IZ, to assess the risk of incidence of fungal diseases on the vine, especially in relation to the incidence of downy mildew (Plasmopara viticola, one of the main grapevine diseases in humid regions. Based on the evaluated indices, it was found that the most favorable period for grape production goes from October to March because of the lower values of rainfall. During the other months, it can be employed branch pruning without fruit production, as occurs in other tropical locations of Brazil. =A videira tem sido cultivada em diferentes regiões tropicais do Brasil. No estado de Roraima, ela foi implantada comercialmente em 2005 em Boa Vista. Ao contrário das regiões de clima temperado, as regiões tropicais apresentam condições térmicas para a produção de uvas durante o ano inteiro. Para se avaliar as características climáticas dos diferentes períodos do ano pode-se recorrer a diversos índices. Objetivou-se, com o presente trabalho, avaliar a aptidão climática de Boa Vista, Roraima, para o cultivo da videira, considerando-se diferentes períodos de produção ao longo do ano. Na caracterização climática, foi utilizado o Sistema de Classificação Climática Multicrit

  5. Correlating Computed Tomography Perfusion Changes in the Pharyngeal Constrictor Muscles During Head-and-Neck Radiotherapy to Dysphagia Outcome

    Energy Technology Data Exchange (ETDEWEB)

    Truong, Minh Tam, E-mail: mitruong@bu.edu [Department of Radiation Oncology, Boston Medical Center and Boston University School of Medicine, Boston, MA (United States); Department of Radiology, Boston Medical Center and Boston University School of Medicine, Boston, MA (United States); Lee, Richard [Department of Radiation Oncology, Boston Medical Center and Boston University School of Medicine, Boston, MA (United States); Saito, Naoko [Department of Radiology, Boston Medical Center and Boston University School of Medicine, Boston, MA (United States); Qureshi, Muhammad M. [Department of Radiation Oncology, Boston Medical Center and Boston University School of Medicine, Boston, MA (United States); Ozonoff, Al [Department of Biostatistics, Boston University School of Public Health, Boston, MA (United States); Romesser, Paul B. [Department of Radiation Oncology, Boston Medical Center and Boston University School of Medicine, Boston, MA (United States); Wang, Jimmy; Sakai, Osamu [Department of Radiology, Boston Medical Center and Boston University School of Medicine, Boston, MA (United States)

    2012-02-01

    Purpose: To measure changes in perfusion of the pharyngeal constrictor muscles (PCM) using CT perfusion (CTP) imaging during a course of definitive radiotherapy (RT) in head-and-neck cancer (HNC) patients and correlate with dysphagia outcome after RT. Methods and Materials: Fifteen HNC patients underwent CTP imaging of the PCM at baseline and Weeks 2, 4, and 6 during RT and 6 weeks after RT. Blood flow and blood volume were measured in the PCM, and percentage change from baseline scan was determined. A single physician-based assessment of dysphagia was performed every 3 months after RT using the Common Terminology Criteria for Adverse Events, version 3.0 grading system. Results: With a median follow-up of 28 months (range, 6-44 months), Grade 3 dysphagia was present in 7 of 15 patients, and 8 patients experienced Grade 0-2 dysphagia. The CTP parameters at Week 2 of RT demonstrated an increase in mean PCM blood flow of 161.9% vs. 12.3% (p = 0.007) and an increase in mean PCM blood volume of 96.6% vs. 8.7% (p = 0.039) in patients with 6-month post-RT Grade 3 dysphagia and Grade 0-2 dysphagia, respectively. On multivariate analysis, when adjusting for smoking history, tumor volume, and baseline dysphagia status, an increase in blood flow in the second week of RT was significant for 3- and 6-month Grade 3 dysphagia (p < 0.05). Conclusions: Perfusion changes in the PCM during Week 2 of RT in the PCM may predict the severity of dysphagia after HNC RT.

  6. The dilemma of parotid gland and pharyngeal constrictor muscles preservation—Is daily online image guidance required? A dosimetric analysis

    Energy Technology Data Exchange (ETDEWEB)

    Duffy, Olivia; Forde, Elizabeth; Leech, Michelle, E-mail: leechm@tcd.ie

    2017-04-01

    With margin reduction common in head and neck radiotherapy, it is critical that the dosimetric effects of setup deviations are quantified. With past studies focusing on the quantification of positional and volumetric changes of organs at risk (OARs), this study aimed to measure the dose delivered to these the parotid gland (PG) and pharyngeal constrictor muscles (PCMs) using cone beam computed tomography (CBCT). Furthermore, this investigation sought to establish a potential time trend of change in dose delivered to target volumes secondary to ascertaining the need for daily image guidance (IG) to reduce the dose burden to these important OARs. Intensity modulated radiotherapy (IMRT) plans for 5 locally advanced head and neck patients' plans were created and mapped to weekly CBCTs. Each plan was recalculated without heterogeneity correction allowing for dosimetric comparison. Dosimetric endpoints recorded to assess the effect of positional variation were as per ICRU 83 and included D{sub 95} and D{sub 98} for the target volumes, mean dose (MD) and V{sub 30} {sub Gy} for the PGs, and V{sub 50} {sub Gy} and MD for the PCMs. Results were deemed statistically significant if p < 0.05. No significant time trends were established for these OARs. A significant decrease in V{sub 50} {sub Gy} was observed for all PCMs (p < 0.001) on all CBCTs relative to the original plan. Regarding target volumes, a highly significant decrease in MD (MD = 20 Gy, CI: −20.310 to −19.820) in D{sub 98} of the high-dose planning target volume (PTV [70 Gy]; PTVD{sub 98%} = 70 Gy) for case 3 was found (p ≤ 0.001). A nonpredictable, yet significant dosimetric effect was found. A clinically acceptable balance must be achieved between OAR dosimetry and target coverage as can be achieved by frequent IG.

  7. Correlating Computed Tomography Perfusion Changes in the Pharyngeal Constrictor Muscles During Head-and-Neck Radiotherapy to Dysphagia Outcome

    International Nuclear Information System (INIS)

    Truong, Minh Tam; Lee, Richard; Saito, Naoko; Qureshi, Muhammad M.; Ozonoff, Al; Romesser, Paul B.; Wang, Jimmy; Sakai, Osamu

    2012-01-01

    Purpose: To measure changes in perfusion of the pharyngeal constrictor muscles (PCM) using CT perfusion (CTP) imaging during a course of definitive radiotherapy (RT) in head-and-neck cancer (HNC) patients and correlate with dysphagia outcome after RT. Methods and Materials: Fifteen HNC patients underwent CTP imaging of the PCM at baseline and Weeks 2, 4, and 6 during RT and 6 weeks after RT. Blood flow and blood volume were measured in the PCM, and percentage change from baseline scan was determined. A single physician-based assessment of dysphagia was performed every 3 months after RT using the Common Terminology Criteria for Adverse Events, version 3.0 grading system. Results: With a median follow-up of 28 months (range, 6–44 months), Grade 3 dysphagia was present in 7 of 15 patients, and 8 patients experienced Grade 0–2 dysphagia. The CTP parameters at Week 2 of RT demonstrated an increase in mean PCM blood flow of 161.9% vs. 12.3% (p = 0.007) and an increase in mean PCM blood volume of 96.6% vs. 8.7% (p = 0.039) in patients with 6-month post-RT Grade 3 dysphagia and Grade 0–2 dysphagia, respectively. On multivariate analysis, when adjusting for smoking history, tumor volume, and baseline dysphagia status, an increase in blood flow in the second week of RT was significant for 3- and 6-month Grade 3 dysphagia (p < 0.05). Conclusions: Perfusion changes in the PCM during Week 2 of RT in the PCM may predict the severity of dysphagia after HNC RT.

  8. First record of Crepidobothrium gerrardii (Cestoda: Proteocephalidae in Peru Primer registro de Crepidobothrium gerrardii (Cestoda: Proteocephalidae en el Perú

    Directory of Open Access Journals (Sweden)

    Luis A. Gomez-Puerta

    2012-02-01

    Full Text Available It is the first record of cestode Crepidobothrium gerrardii in Peru, parasitizing the intestine of a boa constrictor (Boa constrictor from Loreto. Four tapeworms were studied and identified as C. gerrardii.Se registra por primera vez la presencia en el Perú del cestodo Crepidobothrium gerrardii parasitando el intestino de una boa constrictora (Boa constrictor procedente del departamento de Loreto. Cuatro especímenes fueron estudiados e identificados como C. gerrardii.

  9. Study of the radiological procedures used in odontologic clinics of Boa Vista, Roraima, Brazil; Estudo dos procedimentos radiologicos nos consultorios odontologicos de Boa Vista, Roraima

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Jaberson Luiz Leitao

    2002-04-01

    The purpose of this study was to evaluate the radiological procedures used at the odontologic clinics of Boa Vista, Roraima-Brazil. The following parameters were recorded: field diameter, half value layer, total filtration, discrepancy between the preset and the applied kilovoltage and exposure time. Dose to the patient's skin from radiography of the upper molar tooth was also estimated. The results showed that 78% of the inspected units had field diameters larger than 6,0 cm, which is outside the limits recommended by the Brazilian Health Ministry. The results also showed that 14% of the equipment presented a discrepancy of more than 10% between preset and applied kilovoltage. On the other hand, the discrepancy between preset and applied exposure time is higher than 10% in 70% of the tested units. The total filtration of 77% units is lower than 1,5 mm of Al, a value recommended by the Brazilian Health Ministry for equipment that operates in the range of 50 kV to 70 kV. The survey also indicates that for 35% of the units the entrance dose in high than 3,5 mGy that is the reference value established by the Brazilian Health Ministry for dental radiography with film type. It was observed that the majority of the clinics use neither aprons nor collars for patients and that films are processed manually, without controlling temperature or processing time. Based on the results obtained it is strongly recommended that a quality control program be implemented in dental radiological clinics in Boa Vista, Roraima. (author)

  10. Boa leitura!

    Directory of Open Access Journals (Sweden)

    Ana Lúcia Enne

    2007-10-01

    Full Text Available

    Prezado leitor,

    Antes de mais nada, queremos agradecer o número expressivo de artigos submetidos à avaliação nesta última edição: mais de quarenta. Selecionamos quinze para a edição de outubro, que, com prazer, apresentamos agora. Outros tantos, também avaliados positivamente, serão publicados em nossa última edição de 2007, prevista para fins de dezembro. Por fim, queremos reforçar os agradecimentos aos autores que, a partir das considerações de nossos pareceristas, têm reapresentado seus artigos para nova avaliação e possível publicação. Acreditamos que o volumoso feedback que temos recebido, nesse sentido, atesta a compreensão, por parte dos autores, de nossos cuidados editoriais.


    Voltemos, por agora, à edição atual: questões relacionadas à cibercultura são o mote para agruparmos os cinco primeiros artigos, de autoria, respectivamente, de Marcelo Lopes, Filipe Barros, José Cláudio Oliveira, Márcio Padrão e Leonardo Almeida.
    Por sua vez, os trabalhos de Laércio Góes e Lucia Santa Cruz oferecem reflexões importantes sobre formas alternativas de Jornalismo.


    O cinema é o eixo que aproxima os artigos de Erly Vieira Jr, Pedro Lapera, Fábio Ramalho, Airton De Grande e Cristiane Lima. Os três primeiros trazem instigantes abordagens sobre cinema e política, cabendo aos dois últimos considerações sobre o campo do documentário.


    Encerrando a edição, os textos de Felipe Muanis, Sofia Zanforlin e Lílian Moreira têm como foco séries televisivas, a partir de discussões diversas.


    Por último, gostaria de agradecer publicamente à equipe editorial que tem trabalhado comigo no esforço de colocar a Ciberlegenda na rede. São discentes de Mestrado e Doutorado da UFF, todos voluntários, que aceitaram o desafio de editar uma revista de pós-graduação com padrões de qualidade e marcada pelo compromisso com a causa pública. Pelos mesmos motivos, registro aqui minha gratidão com a equipe de pareceristas.

    Ana Lucia Enne – editora

     

     

  11. Boa leitura!

    Directory of Open Access Journals (Sweden)

    Luís Carlos Lopes

    2011-01-01

    Full Text Available

    A Ciberlegenda está completando sete anos de vida. Neste período, o número de seusleitores cresceu enormemente, bem como sua difusão entre os rincões das diásporaslusófonas e hispanofônicas. Somos citados em inúmeros outros sítios e reconhecidoscomo de leitura obrigatória em diversos espaços físicos e virtuais. 

    Consultando-se, em novembro de 2004, o motor de busca Google encontramos 464 menções na WEB referentes à palavra Ciberlegenda. Destas, 311 estão em línguaportuguesa, 111 em espanhol, 31 em inglês e 7 em francês. Manejando o nossocontador, que funciona desde janeiro de 2001 e que já passou da contabilização de 40.000 acessos, verifica-se uma média de 30 acessos/dia ao periódico. Não temoscomo saber quantos destes são relativos a leitores reais.  

    Chegam ao endereço eletrônico do editor correios eletrônicos de várias partes domundo. Agradecemos, em nome do Programa de Pós-Graduação em Comunicação da Universidade Federal Fluminense, os elogios e as outras palavras de incentivo.Alguns, menos avisados, pedem cópias em papel ou desejam assinar o periódico.Quando possível, é esclarecido que a revista só existe no formato eletrônico e que o acesso é livre e sem ônus.

    Alguns leitores mandam contribuições que, infelizmente, não se podem publicar. Ésempre difícil conviver com o corte do material enviado, tanto do ponto de vista doautor, tal como o do editor. Este não tem o poder final sobre o que deve ou não ser publicado, sendo apenas um dos que trabalham na seleção dos textos. Usam-sesempre os pareceres dos membros do comitê e do conselho editoriais. Há problemas de espaço, de pertinência à linha editorial e de qualidade dos textos.

    Nem sempre se tem tempo hábil para responder a todas as solicitações de nossosleitores e colaboradores. Faz-se isto na medida do possível. A nossa revista nãopossui um esquema de produção comercial e nem funcionários para geri-la.Normalmente, ela é publicada a partir da casa e computador pessoal do editor. Desteespaço, ela é enviada aos computadores da Universidade Federal Fluminense, que a abrigam e a mantém Tenta-se manter o mais elevado nível de profissionalismo, dentrodas condições de trabalho  e possibilidades existentes. 

    Nunca é demais esclarecer que os pontos de vista dos autores, bem como a íntegrade seus textos, são de exclusiva responsabilidade dos mesmos. Não se faz censuraideológica ou controle de procedência. Não se introduz qualquer modificação nostextos enviados, a não ser as de caráter absolutamente formais.  Procura-seselecionar os artigos a partir de critérios de qualidade e adequação aos objetivosenunciados nas normas editoriais.  

    Tem sido muito prazeroso editar a Ciberlegenda, mesmo com as dificuldadesinerentes a esta tarefa. Ela já ocupou o seu lugar nas mídias eletrônicas e no universodas demais revistas acadêmicas que escolheram o ciberespaço como um lugarprivilegiado. Se os objetivos principais de revistas desta natureza consistem eminformar e fazer circular amplamente as idéias da comunidade dos pesquisadores, acredita-se que se está no caminho certo. Aliás, o julgamento que realmente importa é o do leitor.  

    A Ciberlegenda é feita para os seus leitores. Eles esperam e cobram insistentementepor cada novo número. Aproximadamente, são realizadas 10.000 consultas por ano. Este último número de 2004 é mais uma vez dedicado aos seus fiéis leitores. Espera-se que em 2005, a revista esteja ainda melhor e que seus leitores continuem sendoseus parceiros ativos, bem como os seus críticos mais construtivos. 

    Rio de Janeiro, 27 de novembro de 2004.

    Luís Carlos Lopes

    Editor

  12. A pedagogia no combate ao trabalho infantil no município de Boa Vista

    Directory of Open Access Journals (Sweden)

    Lysne Nôzenir Camelo de Lima

    2013-09-01

    Full Text Available O trabalho infantil expõe as crianças a vários riscos, prejudicando seu desenvolvimento e configura-se como violação de direito. O trabalho apresenta a pedagogia utilizada pelo PETI em Boa Vista; o procedimento foi aplicado através de entrevista semi-estruturada e questionários, aos gestores e as crianças do programa, com enfoque qualitativo e quantitativo, avaliando a participação e satisfação dos integrantes e seus familiares. O PETI tem a finalidade de erradicar as diversas formas de trabalho infantil, assim como retirar das ruas crianças e/ou adolescentes. Sendo o seu público alvo crianças e/ou adolescentes na faixa etária de 07 (sete a 15 (quinze anos de idade. Dentre as ações desenvolvidas estão a de caráter protetivo e sócioeducativo, que compreendem: atividades ludopedagógicas, palestras preventivas e educativas, esportes, artesanatos, músicas e etc. Nesse contexto, cabe ao PETI, como programa estratégico, contribuindo para erradicação do trabalho infantil no Município de Boa Vista. Oportunizando assim as crianças e adolescentes assim como suas famílias a terem uma vida melhor. No resultado final, constatou-se o compromisso em erradicar o trabalho infantil em Boa Vista, priorizando o atendimento as famílias, através da educação social.

  13. Szász-Durrmeyer operators involving Boas-Buck polynomials of blending type.

    Science.gov (United States)

    Sidharth, Manjari; Agrawal, P N; Araci, Serkan

    2017-01-01

    The present paper introduces the Szász-Durrmeyer type operators based on Boas-Buck type polynomials which include Brenke type polynomials, Sheffer polynomials and Appell polynomials considered by Sucu et al. (Abstr. Appl. Anal. 2012:680340, 2012). We establish the moments of the operator and a Voronvskaja type asymptotic theorem and then proceed to studying the convergence of the operators with the help of Lipschitz type space and weighted modulus of continuity. Next, we obtain a direct approximation theorem with the aid of unified Ditzian-Totik modulus of smoothness. Furthermore, we study the approximation of functions whose derivatives are locally of bounded variation.

  14. Szász-Durrmeyer operators involving Boas-Buck polynomials of blending type

    Directory of Open Access Journals (Sweden)

    Manjari Sidharth

    2017-05-01

    Full Text Available Abstract The present paper introduces the Szász-Durrmeyer type operators based on Boas-Buck type polynomials which include Brenke type polynomials, Sheffer polynomials and Appell polynomials considered by Sucu et al. (Abstr. Appl. Anal. 2012:680340, 2012. We establish the moments of the operator and a Voronvskaja type asymptotic theorem and then proceed to studying the convergence of the operators with the help of Lipschitz type space and weighted modulus of continuity. Next, we obtain a direct approximation theorem with the aid of unified Ditzian-Totik modulus of smoothness. Furthermore, we study the approximation of functions whose derivatives are locally of bounded variation.

  15. Identification of snake arenaviruses in live boas and pythons in a zoo in Germany.

    Science.gov (United States)

    Aqrawi, T; Stöhr, A C; Knauf-Witzens, T; Krengel, A; Heckers, K O; Marschang, R E

    2015-01-01

    Recent studies have described the detection and characterisation of new, snake specific arenaviruses in boas and pythons with inclusion body disease (IBD). The objective of this study was to detect arenaviral RNA in live snakes and to determine if these were associated with IBD in all cases. Samples for arenavirus detection in live animals were compared. Detected viruses were compared in order to understand their genetic variability. Esophageal swabs and whole blood was collected from a total of 28 boas and pythons. Samples were tested for arenaviral RNA by RT-PCR. Blood smears from all animals were examined for the presence of inclusion bodies. Internal tissues from animals that died or were euthanized during the study were examined for inclusions and via RT-PCR for arenaviral RNA. All PCR products were sequenced and the genomic sequences phylogenetically analysed. Nine live animals were found to be arenavirus-positive. Two additional snakes tested positive following necropsy. Five new arenaviruses were detected and identified. The detected viruses were named "Boa Arenavirus Deutschland (Boa Av DE) numbers 1-4" and one virus detected in a python (Morelia viridis) was named "Python Av DE1". Results from sequence analyses revealed considerable similarities to a portion of the glycoprotein genes of recently identified boid snake arenaviruses. Both oral swabs and whole blood can be used for the detection of arenaviruses in snakes. In most cases, but not in all, the presence of arenaviral RNA correlated with the presence of inclusions in the tissues of infected animals. There was evidence that some animals may be able to clear arenavirus infection without development of IBD. This is the first detection of arenaviruses in live snakes. The detection of arenaviruses in live snakes is of importance for both disease detection and prevention and for use in quarantine situations. The findings in this study support the theory that arenaviruses are the cause of IBD, but

  16. On Some Extensions of Szasz Operators Including Boas-Buck-Type Polynomials

    Directory of Open Access Journals (Sweden)

    Sezgin Sucu

    2012-01-01

    Full Text Available This paper is concerned with a new sequence of linear positive operators which generalize Szasz operators including Boas-Buck-type polynomials. We establish a convergence theorem for these operators and give the quantitative estimation of the approximation process by using a classical approach and the second modulus of continuity. Some explicit examples of our operators involving Laguerre polynomials, Charlier polynomials, and Gould-Hopper polynomials are given. Moreover, a Voronovskaya-type result is obtained for the operators containing Gould-Hopper polynomials.

  17. Produtos e subprodutos da medicina popular comercializados na cidade de Boa Vista, Roraima

    OpenAIRE

    PINTO, Angélica Auxiliadora da Costa; MADURO, Cice Batalha

    2003-01-01

    O objetivo deste estudo foi identificar produtos e subprodutos de origem animal e vegetal utilizados na medicina popular que são comercializados na cidade de Boa Vista, Estado de Roraima, traçando um perfil preliminar de sua forma de comercialização. Foram identificados 117 produtos : 100 (85,5 %) de origem vegetal e 17 (14,5 %) de origem animal. Os produtos de origem vegetal de maior destaque foram o Jatobá (Hymenaea courbaril), o Barbatimão (Stryphnodendron adstrinfens), a Sucuba (Himatanth...

  18. Produtos e subprodutos da medicina popular comercializados na cidade de Boa Vista, Roraima

    OpenAIRE

    PINTO,Angélica Auxiliadora da Costa; MADURO,Cice Batalha

    2003-01-01

    O objetivo deste estudo foi identificar produtos e subprodutos de origem animal e vegetal utilizados na medicina popular que são comercializados na cidade de Boa Vista, Estado de Roraima, traçando um perfil preliminar de sua forma de comercialização. Foram identificados 117 produtos : 100 (85,5 %) de origem vegetal e 17 (14,5 %) de origem animal. Os produtos de origem vegetal de maior destaque foram o Jatobá (Hymenaea courbaril), o Barbatimão (Stryphnodendron ads...

  19. Os jardins de Glaziou para a Quinta da Boa Vista, Rio de Janeiro / RJ

    Directory of Open Access Journals (Sweden)

    Jeanne Trindade

    2014-05-01

    Full Text Available O projeto dos jardins da Quinta da Boa Vista foi apresentado ao Imperador D. Pedro II por Auguste François-Marie Glaziou em 1868 e as obras, efetivamente, iniciadas em 1872. Construídos para o deleite não só da família imperial, seus convidados e das pessoas que moravam no interior da propriedade, o acesso era aberto à população em geral aos domingos, talvez, numa tentativa de acalmar os ânimos revolucionários do povo, tal qual acontecera na Inglaterra nos séculos anteriores. Inspirado nos jardins paisagísticos franceses, aliado aos conhecimentos das matas nacionais, o projeto executado por Glaziou para a Quinta da Boa Vista produz grande impacto nos frequentadores devido aos contrastes proporcionados. A utilização maciça de vegetação arbórea — principalmente em suas extremidades — produz um distanciamento visual da cidade que pode promover uma evasão tanto da situação geográfica como de seus problemas, gerando uma sensação de conforto e bem-estar, característica de vários parques da época.

  20. BoA 2 and 3 - Implementation of an innovative power plant concept and first operational experience

    Energy Technology Data Exchange (ETDEWEB)

    Elsen, Reinhold O. [RWE Power AG, Essen (Germany). Research and Development; Schoeddert, Guido [RWE Power AG, Grevenbroich (Germany). BoA Neurath; Hensel, Manfred [RWE Technology GmbH, Grevenbroich (Germany). Site Management

    2013-04-01

    Units F and G of RWE Powers Neurath power plant have been in commercial operation since the summer of 2012. After Niederaussem K, they are the second and third units equipped with BoA technology (BoA = lignite-fired power plant with optimised plant technology). The BoA approach comprises e.g. optimisation measures in connection with the steam turbine, elevated steam parameters, lean design of thick-walled parts in the steam generator, improvements to the auxiliary power consumption, and heat recovery from the flue gases. With a gross rating of 1,100 MW (1,050 MW net) each has a net design efficiency of more than 43% they are the biggest and most modern lignite-fired power plants worldwide.

  1. O desflorestamento ao longo da rodovia BR-174 (Manaus/Am - Boa Vista/Rr / The deforestation along the BR-174 road (Manaus / Am - Boa Vista / Rr

    Directory of Open Access Journals (Sweden)

    Eduardo Paschoal Rodrigues,

    2011-12-01

    Full Text Available Pesquisas indicam que o processo de desflorestamento na Amazônia está associado à abertura de estradas, uma vez que favorece o fluxo migratório, a ocupação de terras e a exploração de madeiras. O objetivo deste trabalho foi analisar o desflorestamento no entorno (20 km da rodovia BR-174 para um período de 30 anos (1978-2008. Foram utilizadas imagens LANDSAT, dados do INPE/PRODES, dados cartográficos e econômicos e trabalhos de campo. Os resultados demonstraram um crescimento do desflorestamento, passando de 622,15 km2 em 1978 para 2.618,58 km2 em 2008. As principais atividades econômicas dos municípios por onde passa a BR-174, exceto Manaus, estão associadas à agropecuária. Em Manaus, o desflorestamento ocorre principalmente na área urbana. Ainda que a construção da BR-174 esteja associada a processos de desflorestamento, a rodovia possui grande importância para a região, pois foi responsável pela ligação terrestre entre duas capitais do norte do país (Manaus/AM e Boa Vista/RR e possibilitou formar comunidades onde são desenvolvidas atividades econômicas e sociais. A criação de projetos de desenvolvimento sustentável é o grande desafio dos governos locais, para agregar valor aos empreendimentos existentes e desenvolver novos modelos de uso e ocupação na região.

  2. Study of the radiological procedures used in odontologic clinics of Boa Vista, Roraima, Brazil

    International Nuclear Information System (INIS)

    Costa, Jaberson Luiz Leitao

    2002-04-01

    The purpose of this study was to evaluate the radiological procedures used at the odontologic clinics of Boa Vista, Roraima-Brazil. The following parameters were recorded: field diameter, half value layer, total filtration, discrepancy between the preset and the applied kilovoltage and exposure time. Dose to the patient's skin from radiography of the upper molar tooth was also estimated. The results showed that 78% of the inspected units had field diameters larger than 6,0 cm, which is outside the limits recommended by the Brazilian Health Ministry. The results also showed that 14% of the equipment presented a discrepancy of more than 10% between preset and applied kilovoltage. On the other hand, the discrepancy between preset and applied exposure time is higher than 10% in 70% of the tested units. The total filtration of 77% units is lower than 1,5 mm of Al, a value recommended by the Brazilian Health Ministry for equipment that operates in the range of 50 kV to 70 kV. The survey also indicates that for 35% of the units the entrance dose in high than 3,5 mGy that is the reference value established by the Brazilian Health Ministry for dental radiography with film type. It was observed that the majority of the clinics use neither aprons nor collars for patients and that films are processed manually, without controlling temperature or processing time. Based on the results obtained it is strongly recommended that a quality control program be implemented in dental radiological clinics in Boa Vista, Roraima. (author)

  3. Histology of the pharyngeal constrictor muscle in 22q11.2 deletion syndrome and non-syndromic children with velopharyngeal insufficiency.

    Science.gov (United States)

    Widdershoven, Josine C C; Spruijt, Nicole E; Spliet, Wim G M; Breugem, Corstiaan C; Kon, Moshe; Mink van der Molen, Aebele B

    2011-01-01

    Plastic surgeons aim to correct velopharyngeal insufficiency manifest by hypernasal speech with a velopharyngoplasty. The functional outcome has been reported to be worse in patients with 22q11.2 deletion syndrome than in patients without the syndrome. A possible explanation is the hypotonia that is often present as part of the syndrome. To confirm a myogenic component of the etiology of velopharyngeal insufficiency in children with 22q11.2 deletion syndrome, specimens of the pharyngeal constrictor muscle were taken from children with and without the syndrome. Histologic properties were compared between the groups. Specimens from the two groups did not differ regarding the presence of increased perimysial or endomysial space, fiber grouping by size or type, internalized nuclei, the percentage type I fibers, or the diameters of type I and type II fibers. In conclusion, a myogenic component of the etiology of velopharyngeal insufficiency in children with 22q11.2 deletion syndrome could not be confirmed.

  4. The emerging farmed fish species meagre (Argyrosomus regius): how culinary treatment affects nutrients and contaminants concentration and associated benefit-risk balance.

    Science.gov (United States)

    Costa, Sara; Afonso, Cláudia; Bandarra, Narcisa Maria; Gueifão, Sandra; Castanheira, Isabel; Carvalho, Maria Luísa; Cardoso, Carlos; Nunes, Maria Leonor

    2013-10-01

    The effect of cooking methods (boiling, grilling, and roasting) on the proximate and mineral composition, contaminants concentration and fatty acids profile was evaluated aiming to understand the benefits and risks associated to the consumption of the emerging farmed fish meagre (Argyrosomus regius). All the treatments led to lower moisture content. After grilling and roasting, the SFA, MUFA and PUFA contents increased. There was no degradation of EPA and DHA during the culinary processes. Significant retention of minerals in grilled and roasted meagre samples was registered. For Pb and Cd there were no concentration differences between culinary treatments and regarding raw fish. Whereas As level was higher in grilled meagre, total Hg and Me-Hg values were augmented in grilled and roasted meagre. The consumption of meagre is advisable due to the low and healthy fat, high selenium and protein content. Grilling would be the best culinary treatment due to the retention of protein, EPA, DHA and minerals. But as the risk of ingestion of Me-Hg content also increases, based on the risk assessment, intake should not exceed two weekly meals, provided that no other important Me-Hg food source is present in the diet. Otherwise, even this maximum threshold should be lower. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. A combined RT-PCR and dot-blot hybridization method reveals the coexistence of SJNNV and RGNNV betanodavirus genotypes in wild meagre (Argyrosomus regius).

    Science.gov (United States)

    Lopez-Jimena, B; Cherif, N; Garcia-Rosado, E; Infante, C; Cano, I; Castro, D; Hammami, S; Borrego, J J; Alonso, M C

    2010-10-01

    To detect the possible coexistence of striped jack nervous necrosis virus (SJNNV) and red-spotted grouper nervous necrosis virus (RGNNV) genotypes in a single fish, a methodology based on the combination of PCR amplification and blot hybridization has been developed and applied in this study. The degenerate primers designed for the PCR procedure target the T4 region within the capsid gene, resulting in the amplification of both genotypes. The subsequent hybridization of these amplification products with two different specific digoxigenin-labelled probes resulted in the identification of both genotypes separately. The application of the RT-PCR protocol to analyse blood samples from asymptomatic wild meagre (Argyrosomus regius) specimens has shown a 46.87% of viral nervous necrosis virus carriers. The combination of RT-PCR and blot hybridization increases the detection rate up to 90.62%, and, in addition, it has shown the coexistence of both genotypes in 18 out of the 32 specimens analysed (56.25%). This study reports the coexistence of betanodaviruses belonging to two different genotypes (SJNNV and RGNNV) in wild fish specimens. This is the first report demonstrating the presence of SJNNV and RGNNV genotypes in the same specimen. This study also demonstrates a carrier state in this fish species for the first time. © 2010 The Authors. Journal compilation © 2010 The Society for Applied Microbiology.

  6. Effect of rearing system on body traits and fillet quality of meagre (Argyrosomus regius, Asso 1801 chilled for a short time

    Directory of Open Access Journals (Sweden)

    Roberta Martelli

    2013-04-01

    Full Text Available The purpose of this study was to evaluate qualitative traits of meagre (Argyrosomus regius from two different rearing systems (land-based tank filled with geothermal water vs offshore sea cage and after short-term storage at chilling temperature (1, 2, or 3 days. Fish originated from the same batch were fed the same diet. Morpho-biometric traits, L*, a*, and b* colour parameters, texture, free water, proximate composition, total lipids, fatty acids, iron, and selenium contents were analyzed in the fillets. Most parameters were affected by rearing system. Compared to tank-reared fish, caged fish were shorter, poorer in visceral fat, and had higher incidence in cavity content and liver, lower incidence in gonads and head. Caged fish also had softer fillets in the epaxial site, which showed a higher tendency towards greenish colour. Caged fish also showed higher lipid content but lower Fe and Se content. Tank-reared fish fillets were more abundant in PUFAn-3, mainly due to DHA (18.54 vs 12.95%; P<0.001 and consequently showed the best healthiness indexes. Minimal changes, mostly involving colour and texture, were detected during the first three days of refrigerated storage. During storage, no significant modification of the parameters investigated could be ascribed to the rearing system. 

  7. Weekly Dose-Volume Parameters of Mucosa and Constrictor Muscles Predict the Use of Percutaneous Endoscopic Gastrostomy During Exclusive Intensity-Modulated Radiotherapy for Oropharyngeal Cancer

    International Nuclear Information System (INIS)

    Sanguineti, Giuseppe; Gunn, G. Brandon; Parker, Brent C.; Endres, Eugene J.; Zeng Jing; Fiorino, Claudio

    2011-01-01

    Purpose: To define predictors of percutaneous endoscopic gastrostomy (PEG) use during intensity-modulated radiotherapy (IMRT) for oropharyngeal cancer. Methods and Materials: Data for 59 consecutive patients treated with exclusive IMRT at a single institution were recovered. Of 59 patients, 25 were treated with hyperfractionation (78 Gy, 1.3 Gy per fraction, twice daily; 'HYPER'); and 34 of 59 were treated with a once-daily fractionation schedule (66 Gy, 2.2 Gy per fraction, or 70 Gy, 2 Gy per fraction; 'no-HYPER'). On the basis of symptoms during treatment, a PEG tube could have been placed as appropriate. A number of clinical/dosimetric factors, including the weekly dose-volume histogram of oral mucosa (OM DVHw) and weekly mean dose to constrictors and larynx, were considered. The OM DVHw of patients with and without PEG were compared to assess the most predictive dose-volume combinations. Results: Of 59 patients, 22 needed a PEG tube during treatment (for 15 of 22, ≥3 months). The best cutoff values for OM DVHw were V9.5 Gy/week 3 and V10 Gy/week 3 . At univariate analysis, fractionation, mean weekly dose to OM and superior and middle constrictors, and OM DVHw were strongly correlated with the risk of PEG use. In a stepwise multivariate logistic analysis, OM V9.5 Gy/week (≥64 vs. 3 ) was the most predictive parameter (odds ratio 30.8, 95% confidence interval 3.7-254.2, p = 0.0015), confirmed even in the no-HYPER subgroup (odds ratio 21, 95% CI 2.1 confidence interval 210.1, p = 0.01). Conclusions: The risk of PEG use is drastically reduced when OM V9.5-V10 Gy/week is 3 . These data warrant prospective validation.

  8. Metabolic regulation in meagre, Argyrosomus regius (Asso, 1801: Study of gene-diet interactions on lipid metabolism

    Directory of Open Access Journals (Sweden)

    Francisca Silva-Brito

    2014-06-01

    profile on fads2 (fatty acyl desaturase gene and elovl5 (fatty acyl elongase gene expression in liver and brain of meagre (Argyrosomus regius. The four isoproteic and isolipidic diets (50% protein and 12% lipid, dry matter basis were formulated with fish oil (FO or a blend of vegetable oils (VO, rapeseed, linseed and soybean, each with selenium (S, 1mg/kg diet or without selenium (NS. Fish were fed ad libitum for 60 days under a controlled rearing conditions (temperature = 20,7 ± 0,7 ºC; pH = 8; O2 = > 6 ppm. Ribonucleic acid (RNA was extracted from two tissues: liver and brain using RNAspin Mini RNAIsolation Kit (GE Healthcare, with includes a step with DNase I to remove the presence of DNA. The integrity of the extracted RNA was verified by agarose electrophoresis. The RNA concentrations were obtained by nanodrop. From the total RNA, 0.5µg were transcribed to complementary DNA (cDNA using iScript Reverse Transcription Supermix for RT-PCR (BioRad following the manufacturer protocol. Gene expression from fads2 and elovl5 were quantified by analysis of RT-PCR. The β-actine was used as a reference gene. On VO diet hepatic fads2 expression was significantly higher, but not elovl5 expression. In brain of VO fed fish, fads2 and elovl5 expression was not significantly different when compared with FO fed fish (Table 1. With selenium supplementation hepatic fads2 expression was lower in FO (P 0.05. The same trend was evident for hepatic elovl5 expression (P> 0.05 (Table1. Recently, Monroig et al. (2013 described the first functional characterization of meagre Fads2 and Elovl5. This work concluded that, unlike most teleosts, the Fads2 pocesses ∆6 and ∆8 activity. However, conversion rates of meagre Fads2 were low when compared to Salmo salar ∆6 Fads_c (Monroig et al., 2011. On the other hand, meagre Elovl5 showed high activity towards C18 and C20. Thus, ∆6/∆8 activity might be ineffective in converting C18 PUFA and therefore an increase of dietary C18 PUFA may

  9. "Different by Degree": Ella Cara Deloria, Zora Neale Hurston, and Franz Boas Contend with Race and Ethnicity.

    Science.gov (United States)

    Hoefel, Roseanne

    2001-01-01

    American Indian ethnographer and linguist Ella Cara Deloria and African American folklorist and writer Zora Neale Hurston did fieldwork for Franz Boas, the father of modern anthropology. Both were shocked by how American racism empowered white people's historical actions. By correcting stereotypes through their work, they reasserted the role of…

  10. New structural design standard for cooling towers. Pilot project BoA 2 and 3 in Neurath; Pilotprojekt der neuen Normengeneration im Kuehlturmbau. Die Naturzugkuehltuerme von BoA 2 and 3 in Neurath

    Energy Technology Data Exchange (ETDEWEB)

    Woermann, Ralf [Kraetzig und Partner Ingenieurgesellschaft fuer Bautechnik mbH, Bochum (Germany); Haupt, Ralf [ALPINE BAU DEUTSCHLAND AG NL Industrie- und Kraftwerksbau, Dortmund (Germany); Ohlmann, Uwe [RWE Power AG, Essen (Germany). Bautechnik

    2010-01-15

    Starting in 2006 RWE Power is erecting two lignite power plants with highly optimized efficiency (BoA) in Neurath near Cologne. These will be the second and third plant of this most advanced technique after the completion of BoA1 in Niederaussem in 2003. The most outstanding buildings of the new power-station are the natural draught cooling towers with a height of 173 m. Their design and execution will be described in this paper. For the first time in cooling tower design the completely revised new edition 2005 of the VGB-Guideline ''Structural Design of Cooling Towers'' was applied in connection with other related new design standards. (orig.)

  11. Comparison of first-intention healing of carbon dioxide laser, 4.0-MHz radiosurgery, and scalpel incisions in ball pythons (Python regius).

    Science.gov (United States)

    Hodshon, Rebecca T; Sura, Patricia A; Schumacher, Juergen P; Odoi, Agricola; Steeil, James C; Newkirk, Kim M

    2013-03-01

    To evaluate first-intention healing of CO(2) laser, 4.0-MHz radiowave radiosurgery (RWRS), and scalpel incisions in ball pythons (Python regius). 6 healthy adult ball pythons. A skin biopsy sample was collected, and 2-cm skin incisions (4/modality) were made in each snake under anesthesia and closed with surgical staples on day 0. Incision sites were grossly evaluated and scored daily. One skin biopsy sample per incision type per snake was obtained on days 2, 7, 14, and 30. Necrotic and fibroplastic tissue was measured in histologic sections; samples were assessed and scored for total inflammation, histologic response (based on the measurement of necrotic and fibroplastic tissues and total inflammation score), and other variables. Frequency distributions of gross and histologic variables associated with wound healing were calculated. Gross wound scores were significantly greater (indicating greater separation of wound edges) for laser incisions than for RWRS and scalpel incisions at all evaluated time points. Necrosis was significantly greater in laser and RWRS incisions than in scalpel incision sites on days 2 and 14 and days 2 and 7, respectively; fibroplasia was significantly greater in laser than in scalpel incision sites on day 30. Histologic response scores were significantly lower for scalpel than for other incision modalities on days 2, 14, and 30. In snakes, skin incisions made with a scalpel generally had less necrotic tissue than did CO(2) laser and RWRS incisions. Comparison of the 3 modalities on the basis of histologic response scores indicated that use of a scalpel was preferable, followed by RWRS and then laser.

  12. Evaluation of the role of the cyclooxygenase signaling pathway during inflammation in skin and muscle tissues of ball pythons (Python regius).

    Science.gov (United States)

    Sadler, Ryan A; Schumacher, Juergen P; Rathore, Kusum; Newkirk, Kim M; Cole, Grayson; Seibert, Rachel; Cekanova, Maria

    2016-05-01

    OBJECTIVE To determine degrees of production of cyclooxygenase (COX)-1 and -2 and other mediators of inflammation in noninflamed and inflamed skin and muscle tissues in ball pythons (Python regius). ANIMALS 6 healthy adult male ball pythons. PROCEDURES Biopsy specimens of noninflamed skin and muscle tissue were collected from anesthetized snakes on day 0. A 2-cm skin and muscle incision was then made 5 cm distal to the biopsy sites with a CO2 laser to induce inflammation. On day 7, biopsy specimens of skin and muscle tissues were collected from the incision sites. Inflamed and noninflamed tissue specimens were evaluated for production of COX-1, COX-2, phosphorylated protein kinase B (AKT), total AKT, nuclear factor κ-light-chain-enhancer of activated B cells, phosphorylated extracellular receptor kinases (ERKs) 1 and 2, and total ERK proteins by western blot analysis. Histologic evaluation was performed on H&E-stained tissue sections. RESULTS All biopsy specimens of inflamed skin and muscle tissues had higher histologic inflammation scores than did specimens of noninflamed tissue. Inflamed skin specimens had significantly greater production of COX-1 and phosphorylated ERK than did noninflamed skin specimens. Inflamed muscle specimens had significantly greater production of phosphorylated ERK and phosphorylated AKT, significantly lower production of COX-1, and no difference in production of COX-2, compared with production in noninflamed muscle specimens. CONCLUSIONS AND CLINICAL RELEVANCE Production of COX-1, but not COX-2, was significantly greater in inflamed versus noninflamed skin specimens from ball pythons. Additional research into the reptilian COX signaling pathway is warranted.

  13. O proletariado, a esperança e o sonho de uma vida boa

    Directory of Open Access Journals (Sweden)

    Suzanna Sochaczewski

    2012-08-01

    Full Text Available O texto discute o conteúdo da esperança da classe trabalhadora no Brasil de nossos dias, considerando as lutas do movimento sindical por melhores condições de trabalho e remuneração e o papel da produção de conhecimento próprio nesse processo. Essa discussão tem como ponto de referência principal o sonho proletário de uma vida boa e a responsabilidade da atual geração de dirigentes sindicais na formação de jovens trabalhadores no sentido da construção de uma utopia para a transformação da sociedade.This paper discusses the subject of the hope of the working class in Brazil in our time, considering the struggles of the union movement for better work conditions and payment, and the role of knowledge production specific to this process. The principal point of reference for this discussion is the proletarian dream of a good life and the responsibility of the present generation of union leaders in the education of young workers in the sense of building a utopia for the transformation of society.

  14. Second COS FUV Lifetime Position: Verification of FUV Bright Object Aperture (BOA) Operations (FCAL4)

    Science.gov (United States)

    Debes, John H.

    2013-05-01

    As part of the calibration of the second lifetime position on the Cosmic Origins Spectrograph (COS) far-ultraviolet (FUV) detectors, observations of the external target, G191-B2B, were obtained with the G130M, G160M, and G140L gratings in combi- nation with the Bright Object Aperture. The observations were designed to verify the performance of these spectroscopic modes by reproducing similar observations taken during the SM4 Servicing Mission Observatory Verification (SMOV) of COS. These observations allowed for a detailed determination of the spatial location and profile of the spectra from the three gratings, as well as a determination of the spectral resolution of the G130M grating prior to and after the lifetime move. In general, the negligi- ble differences which exist between the two lifetime positions can be attributed to slight differences in the optical path. In particular, the spectral resolution appears to be slightly improved. The stability of the absolute and relative flux calibration was investigated for G130M as well using STIS echelle data of G191-B2B. We determine that the COS ab- solute flux calibration with the BOA is accurate to 10%, and flux calibrated data are reproducible at the 1-2% level since SMOV.

  15. The "pseudo-craniovertebral articulation" in the deep-sea fish Stomias boa (Teleostei: Stomiidae).

    Science.gov (United States)

    Schnell, Nalani K; Bernstein, Peter; Maier, Wolfgang

    2008-05-01

    Many predatory deep-sea fishes show highly specialized modifications of their feeding apparatus, e.g., elongate jaws studded with long daggerlike teeth, often combined with a very distensible stomach, to be capable of swallowing relatively large prey. These striking features can be observed in members of the marine teleost family Stomiidae. The present study gives a detailed morphological description of the mesopelagic predatory fish, Stomias boa, based on a combined approach of clearing and double staining, serial sections and dissection. In this genus, large pads made of dense connective tissue extend from the first enlarged neural arch to the ventral side of the chordal sheath, embracing the prominent exoccipitals and thus constituting a kind of double ball- and socket joint for the head. The notochordal occipito-vertebral gap is enlarged, probably not by loss of vertebral centra as is proposed for other genera of the stomiid family, e.g., in Astronesthes or Photostomias. We conclude that this "pseudo-craniovertebral articulation" serves as a functional substitute for the absent vertebrae and strengthens the flexible, anterior part of the vertebral column during extreme dorsal expansion of the gape during prey capture and swallowing. (c) 2007 Wiley-Liss, Inc.

  16. Boas práticas clínicas e aspectos regulatórios em pesquisas com terapia celular

    OpenAIRE

    Bruna Pochmann Zambonato

    2016-01-01

    No campo da pesquisa clínica, o manual de Boas Práticas Clínicas (BPC) é um padrão de qualidade que garante não só que a segurança, os direitos e o bem-estar dos participantes destes estudos sejam protegidos, mas também que a credibilidade e precisão dos dados sejam garantidas. Com o avanço das pesquisas envolvendo terapia celular (TC), são necessários a mesma atenção e acompanhamento dado a ao estudo clínico envolvendo fármacos. Além disso, é necessário que a TC trabalhe de acordo com as Boa...

  17. BOAS PRÁTICAS NA PRODUÇÃO DE MEL NA MICRORREGIÃO DE PAU DOS FERROS

    Directory of Open Access Journals (Sweden)

    Pedro Henrique de Assis Silva

    2011-03-01

    Full Text Available As Boas Práticas de Fabricação (BPF e as Boas Práticas Apícolas abrangem um conjunto de medidas que devem ser adotadas pelas unidades de extração do mel a fim de garantir a qualidade sanitária e aconformidade do produto. O presente trabalho teve como objetivo realizar pesquisas na microrregião de Pau dos Ferros, sobre Processo do mel desde a colheita até seu envase. O levantamento foi feito em quatro cidades da região com visitas a apicultores, que foram submetidos a perguntas relacionadas ao modo de colheita do mel e seu processamento. As pesquisas mostram que, a apicultura na região esta evoluindo, mas precisa de melhorias. PALAVRAS CHAVES: Mel, BPF, BPA, pesquisa.

  18. Histology of the pharyngeal constrictor muscle in 22q11.2 deletion syndrome and non-syndromic children with velopharyngeal insufficiency.

    Directory of Open Access Journals (Sweden)

    Josine C C Widdershoven

    Full Text Available Plastic surgeons aim to correct velopharyngeal insufficiency manifest by hypernasal speech with a velopharyngoplasty. The functional outcome has been reported to be worse in patients with 22q11.2 deletion syndrome than in patients without the syndrome. A possible explanation is the hypotonia that is often present as part of the syndrome. To confirm a myogenic component of the etiology of velopharyngeal insufficiency in children with 22q11.2 deletion syndrome, specimens of the pharyngeal constrictor muscle were taken from children with and without the syndrome. Histologic properties were compared between the groups. Specimens from the two groups did not differ regarding the presence of increased perimysial or endomysial space, fiber grouping by size or type, internalized nuclei, the percentage type I fibers, or the diameters of type I and type II fibers. In conclusion, a myogenic component of the etiology of velopharyngeal insufficiency in children with 22q11.2 deletion syndrome could not be confirmed.

  19. A DESCRIÇÃO COMO FERRAMENTA FUNDAMENTAL PARA UMA BOA COMUNICAÇÃO

    Directory of Open Access Journals (Sweden)

    Sérgio Brasil Fernandes

    2012-07-01

    Full Text Available A descrição é um dos principais modos de organização do discurso, pois é por intermédio dela que se adquire a base fundamental para bem utilizar outras formas de organizar a redação de um texto. A descrição viabiliza a possibilidade de as pessoas terem a noção particular e individual sobre si mesmas e sobre tudo o que as envolve. Enfatiza-se que a construção das imagens que constituem o mundo em que vivemos ocorre através dos cinco sentidos (visão, audição, olfato, paladar e tato e da imaginação criadora do ser humano. Explicitar todos esses aspectos fomentou a elaboração deste estudo que tem por objetivo demonstrar a importância da descrição como ferramenta fundamental para uma boa comunicação. Para isso, utilizou-se a pesquisa bibliográfica de natureza qualitativa como metodologia neste trabalho que se caracteriza como um estudo exploratório. Do referencial teórico que embasou o trabalho, cabe ressaltar que a descrição é a forma mais natural no ser humano de produzir um texto porque os instrumentos do descrever, ou seja, os sentidos humanos, já estão em nós e constituem os elementos vitais da nossa sensibilidade (AMARAL; ANTÔNIO; PATROCÍNIO, 2001. Neste estudo, por meio da análise de diversos tipos de texto, são identificadas técnicas descritivas e formas de influência exercidas pela descrição nos modos de organização do discurso narrativo e argumentativo. Em síntese, é preciso priorizar o estudo da descrição como modo de organização do discurso essencial para a obtenção de conhecimento de mundo e para a realização de uma comunicação precisa e eficaz.

  20. Toward a Tree-of-Life for the boas and pythons: multilocus species-level phylogeny with unprecedented taxon sampling.

    Science.gov (United States)

    Graham Reynolds, R; Niemiller, Matthew L; Revell, Liam J

    2014-02-01

    Snakes in the families Boidae and Pythonidae constitute some of the most spectacular reptiles and comprise an enormous diversity of morphology, behavior, and ecology. While many species of boas and pythons are familiar, taxonomy and evolutionary relationships within these families remain contentious and fluid. A major effort in evolutionary and conservation biology is to assemble a comprehensive Tree-of-Life, or a macro-scale phylogenetic hypothesis, for all known life on Earth. No previously published study has produced a species-level molecular phylogeny for more than 61% of boa species or 65% of python species. Using both novel and previously published sequence data, we have produced a species-level phylogeny for 84.5% of boid species and 82.5% of pythonid species, contextualized within a larger phylogeny of henophidian snakes. We obtained new sequence data for three boid, one pythonid, and two tropidophiid taxa which have never previously been included in a molecular study, in addition to generating novel sequences for seven genes across an additional 12 taxa. We compiled an 11-gene dataset for 127 taxa, consisting of the mitochondrial genes CYTB, 12S, and 16S, and the nuclear genes bdnf, bmp2, c-mos, gpr35, rag1, ntf3, odc, and slc30a1, totaling up to 7561 base pairs per taxon. We analyzed this dataset using both maximum likelihood and Bayesian inference and recovered a well-supported phylogeny for these species. We found significant evidence of discordance between taxonomy and evolutionary relationships in the genera Tropidophis, Morelia, Liasis, and Leiopython, and we found support for elevating two previously suggested boid species. We suggest a revised taxonomy for the boas (13 genera, 58 species) and pythons (8 genera, 40 species), review relationships between our study and the many other molecular phylogenetic studies of henophidian snakes, and present a taxonomic database and alignment which may be easily used and built upon by other researchers

  1. Manual de boas práticas ambientais para a indústria do mobiliário de madeira

    OpenAIRE

    Ribeiro, Ricardo Cristiano Peixoto

    2015-01-01

    Este trabalho tem como finalidade a elaboração de um projeto na área ambiental denominado Manual de Boas Práticas Ambientais para a Indústria do Mobiliário de Madeira. Para conseguir atingir o objetivo proposto, inicialmente foi efetuado um breve enquadramento ao subsetor do mobiliário de madeira a nível nacional, recorrendo à bibliografia disponível apoiada em dados estatísticos de suporte. Foram caracterizados os dois concelhos alvo de estudo, Paços de Ferreira e Paredes por ...

  2. BOA Application on Internet of Vehicle%面向车联网技术的BOA应用研究

    Institute of Scientific and Technical Information of China (English)

    崔建明

    2012-01-01

    Traffic informatization has significantly improved the transport efficiency and the internet of things (IoT) bring more new technology and new methods for the development of traffic informatization. The internet of vehicles (IoV) is subsequently generated and is now under developing. However, it has some technical problems in the application process, such as monitoring the detail component of vehicle. In this paper, a technology is proposed that is accessible the small parts of traffic equipment through BOA technology. If the hardware itself has embedded control interface, can the remote monitor be used to revise the components parameters through integration BOA with the interface. By this way, the whole or parts of the equipments can be monitored and optimized by integrating with the CAN bus. It can even reach a wide range of remoting access and monitoring parameters by setting up separated virtual IPv6 address for the BOA. Finally, the example of the controlled video surveillance with the BOA technology is used to demonstrate the feasibility of this technology.%交通信息化提高了交通效率,物联网技术为交通信息化的发展带来更多新技术、新方法,由此产生了“车联网技术”.物联网技术是一种在发展的新技术,故此车联网技术在应用过程中存在一些技术障碍,如车辆细部部件的监控等.本文提出一种通过BOA技术进行交通设备部件访问的服务技术,如果硬件本身具有嵌入式控制接口,通过BOA技术与这种接口集成可以远程对部件进行监控与参数修改.这样BOA通过CAN总线集成的操作可以对设备整体进行全部部件监控和更多的优化操作,甚至可以对BOA设置单独的虚拟IPv6地址,达到更大范围内的远程参数获取与监控.最后,通过具有BOA技术的可控视频监控实例证明,此种技术可行.

  3. Nature/nurture and the anthropology of Franz Boas and Margaret Mead as an agenda for revolutionary politics

    Directory of Open Access Journals (Sweden)

    Sidney M. Greenfield

    2001-12-01

    Full Text Available There is much more involved in the nature/nurture debate than an abstract theoretical disagreement among dispassionate scientists. Each side of the debate leads logically to significantly different views of the social order and holds different implications for social policy. In this paper I shall argue that Boas' Anthropology with its emphasis on cultural relativism was as much a social and political agenda as it was a scientific theory. The positions on public policy issues he opposed were informed (and rationalized by what its advocates claimed to be science. To be able to counter the discriminatory policy proposals that followed from this science, it was necessary for Boas both to challenge its validity and then replace it with an alternative that would support a more liberal political agenda. This chapter of anthropology's history gains relevance in today's context as neoevolutionary, reductionist theories once more provide "scientific" support for conservative, separatist and often discriminatory social policies.O debate natureza/cultura é muito mais do que um desentendimento teórico e abstrato entre cientistas desapaixonados. Cada lado do debate leva a visões diferentes da ordem social e traz implicações diferentes para políticas sociais. Neste artigo, sugiro que a Antropologia de Boas, com sua ênfase no relativismo cultural, tanto quanto uma teoria científica, foi um programa social e político. As posturas de política pública às quais ele se opunha eram informadas (e racionalizadas por algo apresentado por seus proponentes como ciência. Para combater as propostas discriminatórias que decorriam desta ciência, cabia a Boas desafiar sua validade e substituí-la por uma alternativa que daria apoio a uma agenda política mais liberal. Esse capítulo da história da antropologia assume maior relevância no contexto atual em que teorias néo-evolucionistas e reducionistas mais uma vez fornecem uma base "científica" para pol

  4. Anatomical changes in the pharyngeal constrictors after chemo-irradiation of head and neck cancer and their dose-effect relationships: MRI-based study

    International Nuclear Information System (INIS)

    Popovtzer, Aron; Cao Yue; Feng, Felix Y.; Eisbruch, Avraham

    2009-01-01

    Purpose: Dysfunction of pharyngeal constrictors (PCs) after chemo-irradiation of head and neck (HN) cancer has been proposed as major cause of dysphagia. We conducted prospective MRI study to evaluate anatomical changes in the PCs after chemo-irradiation, to gain insight of the mechanism of their dysfunction and their dose-effect relationships. The PCs were compared to the sternocleidomastoid muscles (SCMs), which receive high doses but do not relate to swallowing. Patients and methods: Twelve patients with stage III-IV HN cancer underwent MRI before and 3 months after completing chemo-irradiation. T1- and T2-weighted signals and muscle thickness were evaluated for PCs (superior, middle, and inferior), and SCMs. Mean muscle doses were determined after registration with the planning CT. Results: T1-weighted signals decreased in both PCs and SCMs receiving >50 Gy (p 2 = 0.34, p = 0.01). The T2 signal changes in the PCs were significantly higher than the T2 changes in the SCMs (p 50 Gy gaining significantly more thickness than PCs receiving lesser doses (p = 0.02). In contrast, the SCM thickness decreased post-therapy (p = 0.002). Conclusions: These MRI-based findings, notably the differences between PCs and SCMs, suggest that underlying causes of PC dysfunction are inflammation and edema, likely consequential to acute mucositis affecting the submucosa-lying PCs. These results support reducing mean PC doses to ≤50 Gy, as well as reducing acute mucositis, to improve long-term dysphagia.

  5. SU-E-J-66: Significant Anatomical and Dosimetric Changes Observed with the Pharyngeal Constrictor During Head and Neck Radiotherapy Elicited From Daily Deformable Image Registration and Dose Accumulation

    International Nuclear Information System (INIS)

    Kumarasiri, A; Siddiqui, F; Liu, C; Kamal, M; Fraser, C; Chetty, I; Kim, J

    2015-01-01

    Purpose: To evaluate the anatomical changes and associated dosimetric consequences to the pharyngeal constrictor (PC) that occurs during head and neck radiotherapy (H&N RT). Methods: A cohort of 13 oro-pharyngeal cancer patients, who had daily CBCT’s for localization, was retrospectively studied. On every 5th CBCT, PC was manually delineated by a radiation oncologist. The anterior-posterior PC thickness was measured at the C3 level. Delivered dose to PC was estimated by calculating daily doses on CBCT’s, and accumulating to corresponding planning CT images. For accumulation, a parameter-optimized B- spline-based deformable image registration algorithm (Elastix) was used, in conjunction with an energy-mass mapping dose transfer algorithm. Mean and maximum dose (Dmean, Dmax) to PC was determined and compared with corresponding planned quantities. Results: The mean (±standard deviation) volume increase (ΔV) and thickness increase (Δt) over the course of 35 total fractions were 54±33% (11.9±7.6 cc), and 63±39% (2.9±1.9 mm), respectively. The resultant cumulative mean dose increase from planned dose to PC (ΔDmean) was 1.4±1.3% (0.9±0.8 Gy), while the maximum dose increase (ΔDmax) was 0.0±1.6% (0.0±1.1 Gy). Patients with adaptive replanning (n=6) showed a smaller mean dose increase than those without (n=7); 0.5±0.2% (0.3±0.1 Gy) vs. 2.2±1.4% (1.4±0.9 Gy). There was a statistically significant (p<0.0001) strong correlation between ΔDmean and Δt (Pearson coefficient r=0.78), and a moderate-to-strong correlation (r=0.52) between ΔDmean and ΔV. Correlation between ΔDmean and weight loss ΔW (r=0.1), as well as ΔV and ΔW (r=0.2) were negligible. Conclusion: Patients were found to undergo considerable anatomical changes to pharyngeal constrictor during H&N RT, resulting in non-negligible dose deviations from intended dose. Results are indicative that pharyngeal constrictor thickness, measured at C3 level, is a good predictor for the dose change to

  6. SU-E-J-66: Significant Anatomical and Dosimetric Changes Observed with the Pharyngeal Constrictor During Head and Neck Radiotherapy Elicited From Daily Deformable Image Registration and Dose Accumulation

    Energy Technology Data Exchange (ETDEWEB)

    Kumarasiri, A; Siddiqui, F; Liu, C; Kamal, M; Fraser, C; Chetty, I; Kim, J [Henry Ford Health System, Detroit, MI (United States)

    2015-06-15

    Purpose: To evaluate the anatomical changes and associated dosimetric consequences to the pharyngeal constrictor (PC) that occurs during head and neck radiotherapy (H&N RT). Methods: A cohort of 13 oro-pharyngeal cancer patients, who had daily CBCT’s for localization, was retrospectively studied. On every 5th CBCT, PC was manually delineated by a radiation oncologist. The anterior-posterior PC thickness was measured at the C3 level. Delivered dose to PC was estimated by calculating daily doses on CBCT’s, and accumulating to corresponding planning CT images. For accumulation, a parameter-optimized B- spline-based deformable image registration algorithm (Elastix) was used, in conjunction with an energy-mass mapping dose transfer algorithm. Mean and maximum dose (Dmean, Dmax) to PC was determined and compared with corresponding planned quantities. Results: The mean (±standard deviation) volume increase (ΔV) and thickness increase (Δt) over the course of 35 total fractions were 54±33% (11.9±7.6 cc), and 63±39% (2.9±1.9 mm), respectively. The resultant cumulative mean dose increase from planned dose to PC (ΔDmean) was 1.4±1.3% (0.9±0.8 Gy), while the maximum dose increase (ΔDmax) was 0.0±1.6% (0.0±1.1 Gy). Patients with adaptive replanning (n=6) showed a smaller mean dose increase than those without (n=7); 0.5±0.2% (0.3±0.1 Gy) vs. 2.2±1.4% (1.4±0.9 Gy). There was a statistically significant (p<0.0001) strong correlation between ΔDmean and Δt (Pearson coefficient r=0.78), and a moderate-to-strong correlation (r=0.52) between ΔDmean and ΔV. Correlation between ΔDmean and weight loss ΔW (r=0.1), as well as ΔV and ΔW (r=0.2) were negligible. Conclusion: Patients were found to undergo considerable anatomical changes to pharyngeal constrictor during H&N RT, resulting in non-negligible dose deviations from intended dose. Results are indicative that pharyngeal constrictor thickness, measured at C3 level, is a good predictor for the dose change to

  7. 世界上最大的海洋工程施工船%Boa Deep C the world largest construction vessel

    Institute of Scientific and Technical Information of China (English)

    俞强

    2005-01-01

    Boa DeepC号是目前世界上最大的海洋工程船。从各方面来看,Boa Deep C号是一艘十分特别的船舶,它主要用来从事海底结构的施工、系统的安装、管线修理等,其独立工作的最大深度为2000米,适应于世界各水域。

  8. Árvores frutíferas nos quintais urbanos de Boa Vista, Roraima, Amazônia brasileira Fruit trees in urban home gardens of Boa Vista, Roraima, Brazilian Amazonia

    Directory of Open Access Journals (Sweden)

    Rui Jorge da Conceição Gomes Semedo

    2007-01-01

    Full Text Available O objetivo do trabalho foi estimar a riqueza e a diversidade das espécies de árvores frutíferas cultivadas nos quintais caseiros da cidade de Boa Vista, Roraima, bem como determinar quais são as espécies cultivadas preferencialmente pela população urbana local. Os levantamentos foram realizados em dois bairros surgidos com a expansão da cidade em 1982: (1 BEst - Bairro dos Estados (Zona Norte e (2 BAsa - Bairro Asa Branca (Zona Oeste. Foram observados 722 quintais no BEst (06 a 22.03.2004 e 339 no BAsa (07.04 a 01.07.2004. Trinta e seis espécies (19 famílias botânicas foram encontradas no BEst e 37 (20 famílias no BAsa, configurando um total de 43 espécies (20 famílias observadas. Deste total, 30 espécies (69,8% de 19 famílias (95% ocorreram em ambos os bairros, sugerindo preferências frutíferas comuns. Os três maiores índices de valor de preferência (IVP foram coincidentes e registrados para coco (Cocos nucifera L. - BEst: 19,4% e BAsa: 20,5%, manga (Mangifera indica L. - BEst: 14,9% e BAsa: 22,5% e jambo (Syzygium malaccence (L. Merr. & L.M. Perry - BEst: 10,5% e BAsa: 10,1%, todos de origem externa à Amazônia, mas que congregaram conjuntamente 44,9% (BEst e 53,0% (BAsa de IVP. Estes resultados sugerem que o cultivo de árvores frutíferas em quintais caseiros de Boa Vista segue um padrão que concentra a escolha em poucas espécies, não-originárias da Amazônia, mas tradicionalmente consagradas por seu êxito na produção de frutos.The objective of this study was to estimate the richness and the diversity of fruit tree species cultivated in Boa Vista's home gardens, as well as to determine what species the local urban population prefers. Two neighborhoods that originated during the city's expansion in 1982 were sampled: (1 BEst - Bairro dos Estados (North Zone and (2 BAsa - Bairro Asa Branca (West Zone. Seven hundred and twenty-two home gardens were surveyed in BEst (March 6 to 22, 2004, and 339 in BAsa (April 7 to

  9. A multi-physics code system based on ANC9, VIPRE-W and BOA for CIPS evaluation

    International Nuclear Information System (INIS)

    Zhang, B.; Sung, Y.; Secker, J.; Beard, C.; Hilton, P.; Wang, G.; Oelrich, R.; Karoutas, Z.; Sung, Y.

    2011-01-01

    This paper summarizes the development of a multi-physics code system for evaluation of Crud Induced Power Shift (CIPS) phenomenon experienced in some Pressurized Water Reactors (PWR). CIPS is an unexpected change in reactor core axial power distribution, caused by boron compounds in crud deposited in the high power fuel assemblies undergoing subcooled boiling. As part of the Consortium for Advanced Simulation of Light Water Reactors (CASL) sponsored by the US Department of Energy (DOE), this paper describes the initial linkage and application of a multi-physics code system ANC9/VIPRE-W/BOA for evaluating changes in core power distributions due to boron deposited in crud. The initial linkage of the code system along with the application results will be the base for the future CASL development. (author)

  10. A multi-physics code system based on ANC9, VIPRE-W and BOA for CIPS evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, B.; Sung, Y.; Secker, J.; Beard, C.; Hilton, P.; Wang, G.; Oelrich, R.; Karoutas, Z.; Sung, Y. [Westinghouse Electric Company LLC, Pittsburgh (United States)

    2011-07-01

    This paper summarizes the development of a multi-physics code system for evaluation of Crud Induced Power Shift (CIPS) phenomenon experienced in some Pressurized Water Reactors (PWR). CIPS is an unexpected change in reactor core axial power distribution, caused by boron compounds in crud deposited in the high power fuel assemblies undergoing subcooled boiling. As part of the Consortium for Advanced Simulation of Light Water Reactors (CASL) sponsored by the US Department of Energy (DOE), this paper describes the initial linkage and application of a multi-physics code system ANC9/VIPRE-W/BOA for evaluating changes in core power distributions due to boron deposited in crud. The initial linkage of the code system along with the application results will be the base for the future CASL development. (author)

  11. CASL L1 Milestone report: CASL.P4.01, sensitivity and uncertainty analysis for CIPS with VIPRE-W and BOA

    International Nuclear Information System (INIS)

    Sung, Yixing; Adams, Brian M.; Secker, Jeffrey R.

    2011-01-01

    The CASL Level 1 Milestone CASL.P4.01, successfully completed in December 2011, aimed to 'conduct, using methodologies integrated into VERA, a detailed sensitivity analysis and uncertainty quantification of a crud-relevant problem with baseline VERA capabilities (ANC/VIPRE-W/BOA).' The VUQ focus area led this effort, in partnership with AMA, and with support from VRI. DAKOTA was coupled to existing VIPRE-W thermal-hydraulics and BOA crud/boron deposit simulations representing a pressurized water reactor (PWR) that previously experienced crud-induced power shift (CIPS). This work supports understanding of CIPS by exploring the sensitivity and uncertainty in BOA outputs with respect to uncertain operating and model parameters. This report summarizes work coupling the software tools, characterizing uncertainties, and analyzing the results of iterative sensitivity and uncertainty studies. These studies focused on sensitivity and uncertainty of CIPS indicators calculated by the current version of the BOA code used in the industry. Challenges with this kind of analysis are identified to inform follow-on research goals and VERA development targeting crud-related challenge problems.

  12. CASL L1 Milestone report : CASL.P4.01, sensitivity and uncertainty analysis for CIPS with VIPRE-W and BOA.

    Energy Technology Data Exchange (ETDEWEB)

    Sung, Yixing (Westinghouse Electric Company LLC, Cranberry Township, PA); Adams, Brian M.; Secker, Jeffrey R. (Westinghouse Electric Company LLC, Cranberry Township, PA)

    2011-12-01

    The CASL Level 1 Milestone CASL.P4.01, successfully completed in December 2011, aimed to 'conduct, using methodologies integrated into VERA, a detailed sensitivity analysis and uncertainty quantification of a crud-relevant problem with baseline VERA capabilities (ANC/VIPRE-W/BOA).' The VUQ focus area led this effort, in partnership with AMA, and with support from VRI. DAKOTA was coupled to existing VIPRE-W thermal-hydraulics and BOA crud/boron deposit simulations representing a pressurized water reactor (PWR) that previously experienced crud-induced power shift (CIPS). This work supports understanding of CIPS by exploring the sensitivity and uncertainty in BOA outputs with respect to uncertain operating and model parameters. This report summarizes work coupling the software tools, characterizing uncertainties, and analyzing the results of iterative sensitivity and uncertainty studies. These studies focused on sensitivity and uncertainty of CIPS indicators calculated by the current version of the BOA code used in the industry. Challenges with this kind of analysis are identified to inform follow-on research goals and VERA development targeting crud-related challenge problems.

  13. SU-F-T-107: Correlations Between Dosimetric Indices of Pharyngeal Constrictors and Proximal Esophagus with Associated Patient-Reported Outcomes Six Months After Radiation Therapy for Head and Neck Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Chera, B; Price, A; Kostich, M; Green, R; Das, S; Mavroidis, P [University of North Carolina, Chapel Hill, North Carolina (United States); Amdur, R; Mendenhall, W [University of Florida, Gainesville, FL (United States); Sheets, N [University of North Carolina, Raleigh, North Carolina (United States); Marks, L [UNC School of Medicine, Chapel Hill, NC (United States)

    2016-06-15

    Purpose: To compare the correlations between different dosimetric indices derived from the pharyngeal constrictor muscles and proximal esophagus with patient-reported difficulty in swallowing 6 months post radiotherapy using a novel patient reported outcome version of CTCAE (PRO-CTCAE). Methods: Forty-three patients with oropharyngeal squamous cell carcinoma were treated on a prospective multi-institutional study. All patients received de-intensified 60 Gy intensity modulated radiotherapy. We investigated correlations of individual patient dosimetric data of the superior (SPC), middle (MPC), inferior (IPC) pharyngeal constrictor muscles, the superior esophagus (SES), and the inferior esophagus (IES) to their self-reported 6 month post-treatment swallowing difficulty responses. Mild (≥ Grade 1) swallowing difficulty responses were used as the clinical endpoint indicating response. The predictive efficacy of Dmean and dose-volume (VD) points were assessed through the area under the Receiver Operating Characteristic curve (ROC) and Odds Ratio (OR). Results: The SES and SPC had more favorable area under the curves (AUC) for the Dmean (0.62 and 0.70) while the Dmean to the IPC, MPC, and IES produced suboptimal AUCs (0.42, 0.48, and 0.52). Additionally, over the range of VD, the V54 and V55 for the SES and SPC demonstrated the highest AUCs: AUC(SES) = 0.76–0.73 and AUC(SPC) = 0.72–0.69, respectively. The IES, IPC, and MPC had worse AUC results over the range of VD. An optimal OR can be found when V54 = 96% for the SPC, where OR = 3.96 (1.07–14.62). Conclusion: The V45 and V55 of the SES and SPC had the highest correlation to the clinical endpoint compared to the commonly used dosimetric index, Dmean for both the esophagus and constrictor muscles. The reported dosimetric data demonstrates that new dosimetric indices may need to be considered in the setting of dose de-escalation and self-reported outcomes.

  14. Physical and catalytic characterization of smectites from Boa-Vista, Paraíba, Brazil Caracterização física e catalítica de esmectitas de Boa Vista, Paraíba, Brasil

    Directory of Open Access Journals (Sweden)

    M. G. F. Rodrigues

    2003-09-01

    Full Text Available The original crystalline structure of clay minerals can be altered in a controlled way, through acid or thermal treatments, resulting then in suitable products to be used as catalysts. This paper aims to characterize the red smectite clays of Boa-Vista, Paraíba (Brazil in their natural form, and after chemical, thermal and acid treatments by X-ray fluorescence, differential thermal analysis, dynamic X-ray diffraction, classic X-ray diffraction analysis, scanning electron microscopy, nitrogen adsorption and model reaction. The results show that acid treatment partially altered the structure of the montimorillonite. An important increase in the surface area of the solid obtained was observed. The obtained reaction for the treated material showed that the clay was more acid than the natural one, yielding a better catalytic activity.A estrutura cristalina original dos argilominerais pode ser alterada de um modo controlado através de tratamentos ácidos ou tratamentos químicos, resultando em produtos satisfatórios para serem usados como catalisadores. O objetivo deste trabalho é caracterizar a argila esmectítica vermelha de Boa-Vista, Paraíba (Brasil na sua forma natural e após tratamentos químicos e térmicos. Os métodos usados foram fluorescência de raios X, análise térmica diferencial, difração de raios X, microscopia eletrônica de varredura, adsorção física de nitrogênio e reação modelo. Os resultados mostram que o tratamento ácido alterou parcialmente a estrutura da montmorilonita. Foi observado um importante aumento na área específica do sólido obtido. A reação obtida para o material tratado mostrou que a argila foi mais ácida que a natural conduzindo a uma melhor atividade catalítica.

  15. Species of Anastrepha (Diptera: Tephritidae) captured in a guava orchard (Psidium guajava L., Myrtaceae) in Boa Vista, Roraima, Brazil.

    Science.gov (United States)

    Marsaro Júnior, A L; Deus, E G; Ronchi-Teles, B; Adaime, R; Silva Júnior, R J

    2013-11-01

    The guava fruit (Psidium guajava) is among the most strongly affected by fruit flies in Brazil. In the Brazilian Amazon, 11 species of Anastrepha have been reported in guava orchards to date. This work aimed to identify the species of Anastrepha present in a guava orchard in the municipality of Boa Vista, determine the species infesting the fruits, and identify any parasitoids present. Two McPhail traps with food bait were installed and weekly collections were made between January and December 2008. Fruits were also collected systematically during this period, with a view to determining the association between host plant and tephritid species. Nine species of Anastrepha were identified, in addition to one specimen belonging to a probable new species. Anastrepha striata Schiner, Anastrepha sororcula Zucchi, Anastrepha obliqua (Macquart), and Anastrepha fraterculus (Wiedemann) were the dominant species in the orchard, accounting for 84.8% of all captured individuals. All females collected directly from fruits were A. striata. Doryctobracon areolatus (Szépligeti) was the only parasitoid species obtained. In this work, Anastrepha ethalea (Walker) is reported for the first time in the state of Roraima.

  16. NOVAS PERSPECTIVAS DA RESPONSABILIDADE PROCESSUAL NO BRASIL: O PRINCÍPIO DA BOA-FÉ OBJETIVA E O DEVIDO PROCESSO LEGAL

    Directory of Open Access Journals (Sweden)

    Thiago Rodrigues de Pontes Bomfim

    2016-09-01

    Full Text Available O presente estudo busca, inicialmente, demonstrar o caráter normativo dos princípios constitucionais, bem como seu papel no que acaba por se transformar em uma nova ordem processual, para, por fim, uma vez reconhecido o caráter de princípio jurídico à boa-fé objetiva, situar seu fundamento constitucional em um novo conceito de devido processo legal.

  17. Ocorrência de moscas-das-frutas (Diptera: Tephritidae em mangueiras (Mangifera indica L. em Boa Vista, Roraima = The occurrence of fruit fly (Diptera: Tephritidae in mango (Mangifera indica L. in Boa Vista, Roraima

    Directory of Open Access Journals (Sweden)

    Adriana Bezerra Lima

    2012-08-01

    Full Text Available Um estudo foi conduzido no período de junho de 2007 a janeiro de 2008, em pomares comerciais de manga das variedades: Tommy Atkins, Haden e Palmer sendo 3 ha de cada cultivar, localizado na região do Bom Intento no Município de Boa Vista. Os espécimes de moscas-das-frutas foram coletados, por meio de armadilhas, confeccionadas com garrafas pet, que foram penduradas na copa das árvores a 1,60 m de altura. Como atrativo alimentar foi utilizado 200 mL de suco de maracujá a 30%. Foram utilizadas nove armadilhas, sendo uma armadilha por hectare. Semanalmente as armadilhas eram examinadas, ocasião em que se substituía o atrativo e os insetos capturados retirados e colocados em frascos de vidro devidamente etiquetados e transportados ao Laboratório de Entomologia do Centro de Ciências Agrárias da Universidade Federal de Roraima. As identificações dos espécimes foram feitas no Instituto Nacional de Pesquisa da Amazônia - INPA. No período de oito meses foram coletados 24 espécimes adultos do gênero Anastrepha (nove fêmeas e 15 machos. Quatro espécies foram identificadas: A. serpentina, A. striata, A. obliqua e A. turpinae. A maior frequência foi A. serpentina (44,44%, seguida de A. striata e A. obliqua ambas com 22,22% e A. turpinae com 11,11%. Os meses de maior ocorrência de Anastrepha spp. foram junho, julho e agosto. Este é o primeiro registro da espécie Anastrepha turpinae Stone, 1942, em Roraima. The study was done during th period of June 2007 to January of 2008, in commercial mango orchards having: 3 ha of cv. Tommy Atkins, 3 ha of cv. Haden. and 3 ha of cv. Palmer, located at Bom Intento in the municipal district of Boa Vista - RR. The specimens of fruit flies were collected, by trapping, made with transparent bottles pet, which were hung in the cup of the trees at 1.60 m of height. 200 mL of passion fruit juice (30% was used as an attractant feed; 9 traps were used, being one trap for hectare. Weekly The traps were

  18. Quality assessment of fruit pulps industrialized and commercialized in the city of Boa Vista – RR = Avaliação da qualidade de polpas de frutos industrializadas e comercializadas no município de Boa Vista – RR

    Directory of Open Access Journals (Sweden)

    Cássia Rejane Nascimento

    2012-12-01

    Full Text Available This work aimed to study the quality of frozen pulp, manufactured and marketed in Boa Vista - RR, through physico-chemical analysis. It were selected six Agroindustries that produce and market pulp in establishments located in Fair Passarão, supermarkets and home of juices, identified by the letters A, B, C, D, E and F. The variables studied were: soluble solids, titratable acidity and vitamin C, of the flavors: acerola, caja, cupuaçu, guava, soursop and passion fruit. The experiment was conducted in completely randomized design, being analyzed six brands of fruits pulps and six different fruits, with three replicates. The observed results demonstrate that none of the companies processing fruit pulp detail their identification inaccordance with the legislation. In the variables studied, only the cupuaçu pulp brands C and D and soursop brands B, C, D and E were in accordance with the technical regulation for fixing the identity and quality standard. Considering the variables in question, it was found that variations in the levels encountered and not adequacy of these standards could be minimized by the standardization of raw materials and processes used. =Objetivou-se com o presente trabalho estudar a qualidade de polpas congeladas, fabricadas e comercializadas no município de Boa Vista – RR, por meio de análises físico-químicas. Foram selecionadas seis Agroindústrias que produzem polpa e comercializam em estabelecimentos próprios localizados na Feira do Passarão, supermercados e casa de sucos, sendo identificadas pelas letras A, B, C, D, E e F. As variáveis estudadas foram: sólidos solúveis, acidez titulável e vitamina C, dos sabores: acerola, cajá, cupuaçu, goiaba, graviola e maracujá. O experimento foi conduzido em delineamento inteiramentecasualizado, sendo analisadas seis marcas de polpas e seis frutos diferentes, com três repetições. Os resultados observadosdemonstram que nenhuma das empresas de processamento de polpa

  19. Desenvolvimento e validação de indicadores de boas práticas de segurança do paciente: Projeto ISEP-Brasil

    Directory of Open Access Journals (Sweden)

    Zenewton André da Silva Gama

    Full Text Available Resumo: Um monitoramento eficaz da segurança do paciente precisa focar a implantação de práticas baseadas em evidências que evitem danos desnecessários ligados à assistência à saúde. O objetivo do Projeto ISEP-Brasil foi desenvolver e validar indicadores de boas práticas de segurança do paciente para o contexto brasileiro. Tomou por base a tradução e adaptação dos indicadores validados no Projeto ISEP-Espanha, além do documento Safe Practices for Better Healthcare do National Quality Forum dos Estados Unidos, que possui 34 recomendações de boas práticas. Realizou-se validação por um painel de 25 especialistas e análise da confiabilidade e viabilidade em um estudo-piloto realizado em três hospitais com diferentes tipos de gestão (estadual, federal e privada. Aprovaram-se 75 indicadores de boas práticas (39 de estrutura; 36 de processo para 31 das 34 recomendações. Os indicadores foram considerados válidos, confiáveis e úteis para o monitoramento da segurança do paciente em hospitais brasileiros.

  20. Sistema especialista como ferramenta de apoio às boas práticas de manejo da tilapicultura

    Directory of Open Access Journals (Sweden)

    Ana Flavia Rodrigues Seixas

    2009-12-01

    Full Text Available A piscicultura brasileira, tem impulsionado a economia devido ao seu crescimento em torno de 30% ao ano, como também por tratar-se de fonte de proteína de alta qualidade e pela alta lucratividade. De origem africana, a tilapicultura está presente hoje em grande parte do território nacional, mas ainda sofrendo as pressões por maior qualidade do produto e adoção de práticas menos impactantes ao ambiente. Entre alguns desses impactos citam-se as poluição e interferências em níveis de biodiversidade e de qualidade da água. Assim, o produtor carece de informação e ferramentas que favoreçam a rápida transferência de práticas já identificadas pela pesquisa, que aumentem seu conhecimento e agilidade na incorporação destas às atividades da propriedade. O projeto “ Manejo e Gestão Ambiental da Aqüicultura” da Embrapa Meio Ambiente, componente do projeto em rede Aquabrasil, vem identificando Boas Práticas de Manejo (BPM de tilápia passíveis de uso imediato pelo produtor a partir de sua rápida observação da propriedade. Nele, o sistema informatizado Aquisys está em desenvolvimento para viabilizar o acesso dinâmico, via web, às avaliações e indicadores de produção, manejo e qualidade de água em atenção às BPM de tilápia. Este trabalho apresenta uma das ferramentas computacionais desenvolvidas: um sistema especialista de rápida avaliação de BPM na propriedade, desenvolvido em linguagem CLIPS.

  1. BOA CALL NAME

    Institute of Scientific and Technical Information of China (English)

    凤梨味的Orange

    2013-01-01

    BoA主演的《期待恋爱》即将和大家见面,因为是她自己真正意义上的第一部电视剧,所以自然收获了很多期待与关注。除此之外,新单曲的发行时间也提上了日程。出道13年后,她依然忙碌。

  2. SU-F-T-104: Determining the NTCP Parameters of Pharyngeal Constrictors and Proximal Esophagus for Radiation Induced Swallowing Problems Recorded Six Months After Radiation Therapy for Head and Neck Tumors

    Energy Technology Data Exchange (ETDEWEB)

    Mavroidis, P; Price, A; Kostich, M; Green, R; Das, S; Marks, L; Chera, B [University North Carolina, Chapel Hill, NC (United States); Amdur, R; Mendenhall, W [University of Florida, Gainesville, FL (United States); Sheets, N [University of North Carolina, Raleigh, NC (United States)

    2016-06-15

    Purpose: To estimate the radiobiological parameters of four NTCP models that describe the dose-response relations of pharyngeal constrictors and proximal esophagus regarding the severity of patient reported swallowing problems 6 months post chemo-radiotherapy. To identify the section/structure that best correlates with the manifestation of the clinical endpoints. Finally, to compare the goodness-of-fit of those models. Methods: Forty-three patients were treated on a prospective multi-institutional phase II study for oropharyngeal squamous cell carcinoma. All the patients received 60 Gy IMRT and they reported symptoms using the novel patient reported outcome version of the CTCAE. We derived the individual patient dosimetric data of superior, medium and inferior sections of pharyngeal constrictors (SPC, MPC and IPC), superior and inferior sections of esophagus (SES and IES) as separate structures as well as combinations. The Lyman-Kutcher-Burman (LKB), Relative Seriality (RS), Logit and Relative Logit (RL) NTCP models were used to fit the patient data. The fitting of the different models was assessed through the area under the receiver operating characteristic curve (AUC) and the Odds Ratio methods. Results: The AUC values were highest for the SPC for Grade ≥ 2 (0.719 for the RS and RL models, and 0.716 for LKB and Logit). For Grade ≥ 1, the respective values were 0.699 for RS, LKB and Logit and 0.676 for RL. For MPC the AUC values varied between 0.463–0.477, for IPC between 0.396–0.458, for SES between 0.556–0.613 and for IES between 0.410–0.519. The Odds Ratio for the SPC was 15.6 (1.7–146.4) for RS, LKB and Logit for NTCP of 55%. Conclusion: All the examined NTCP models could fit the clinical data with similar accuracy. The SPC appear to correlate best with the clinical endpoints of swallowing problems. A prospective study could establish the use of NTCP values of SPC as a constraint in treatment planning.

  3. Quem aprende na Educação Infantil? a escola ensinando a ser boa-mãe

    Directory of Open Access Journals (Sweden)

    Letícia Prezzi Fernandes

    2006-01-01

    Full Text Available Esta pesquisa se propôs a problematizar, através dos Estudos de Gênero e Culturais Pós-Estruturalistas, as relações entre professoras e mães de alunos na Educação Infantil. Entende-se que os discursos da pedagogia, da medicina e da psicologia do desenvolvimento, que fundamentam a formação docente, instituem não só posições de sujeito e identidades de professor/a e aluno/a mas, também, determinadas formas de exercício da maternidade. A partir da análise cultural se problematizam alguns ensinamentos sobre maternidade que tanto são produzidos nas relações escolares, como ao mesmo tempo são configurados. Foi observada uma turma de Educação Infantil, atentando para as práticas discursivas que permeiam as relações entre mães e professora, materializadas através dos bilhetes de agenda e dos contatos na entrada e saída da aula, bem como aquelas que delimitam e atravessam as práticas pedagógicas desenvolvidas, sobretudo na semana do dia das mães. Apesar da ênfase atualmente atribuída à participação da família-mãe na escola, estas são chamadas apenas em momentos definidos e delimitados pela escola e pela professora. De fato, a participação da instituição escolar na valoração e legitimação de determinadas formas de exercício da maternidade é bastante intensa, pois a representação de boa-mãe é definida em sutis falas do cotidiano escolar, onde cenas familiares são suscitadas. Entendendo que essas relações têm efeitos pedagógicos importantes pode se observar que, por um lado elas educam as mães das crianças para exercerem uma maternidade definida como aceitável pela instituição, ao mesmo tempo em que ensinam às crianças como suas mães devem ser. Palavras-chave: Produção de Maternidade. Escolas Infantis. Relação Mães/ Educadoras.

  4. BOA技术在车辆感知网络中的应用研究%Applied research on BOA technology in the internet of vehicle

    Institute of Scientific and Technical Information of China (English)

    崔建明

    2012-01-01

    “车联网技术”的兴起,大量传感技术得到应用,受无线传输设备与传感器体积限制,信息只能单向传递,缺少与被感知设备间交互。提出一种通过BOA技术远程感知交通设备中部件访问的双向交互技术,配合虚拟独立地址技术可以达到部件分组独立控制。这样BOA通过CAN总线集成可以对设备整体进行全部部件监控和更多的优化操作.达到更大范围内的远程参数获取与监控。最后,通过具有BOA技术的实例证明,此种技术可行。%The rise of the internet of vehicle (IoV), a large number of sensor technology has been applied ,and because there are some limits that the wireless transmission device and the sensor size, information pass in only one-way, the lack of interaction with the be sensing equipment. It has been proposed that a two-way interactive technology for access the traffic equipment parts by the BOA remote sensing, the components grouping can be achieved independent control with the virtual independent address technology. In this way, BOA can monitor all parts in whole equipment and more optimization operating by integrated CAN-BUS, and reach for remote get 他 the parameter of the equipment and monitor it in a wider range. Finally, examples of the BOA technology show that the technical is feasible.

  5. Esquistossomose mansoni autóctone e outras parasitoses intestinais em escolares do bairro alto da Boa Vista, da Cidade do Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    Virginia T. Schall

    1985-09-01

    Full Text Available Procedeu-se a um levantamento coproscópico em alunos de 8 a 15 anos, pertencentes a 3 escolas do Alto da Boa Vista. De 155 alunos examinados, encontraram-se 4 casos positivos (2,6% de esquistossomose. Entre 25 familiares destes, encontraram-se outros 4 casos positivos (16%. Havia na área uma população de Biomphalaria tenagophila (Orbigny, 1835, amplamente distribuída nas valas de irrigação de hortas de agrião, ligadas ao rio das Fumas. A taxa de infecção dos moluscos foi de 7 (0,29% em 2.400 examinados. Comparando-se estes resultados com dados anteriores, observa-se que a prevalência da esquistossomose se mantém no Alto da Boa Vista há pelo menos 15 anos.The present situation regarding schistosomiasis mansoni prevalence among primary school children was evaluated in the periphery of Rio de Janeiro city (Alto da Boa Vista. A coproscopic survey was carried out with students of 8 to 15 years oldfrom 3 schools of the area. Among 15 5 examined, 4 positive cases (2,6% of schistosomiasis were found. On examining 25 relatives of the positive students, 4 other positives cases (16% were found, all from the same region. The malacological survey carried out revealed a Biomphalaria tenagophila population largely distributed in the irrigation ditches of water-cress gardens surrounding the Fumas River. Seven (7 out of2400 snails collected were positive for Schistosoma mansoni (0,29%. Comparing these results with previous data, it can be observed that schistosomiasis prevalence has been maintained in this area for as long as 15 years. Stool examinations revealed a high prevalence of A. lumbricoides (48,4%. E. nana (23,5% and T. trichiura (38%.

  6. Ocorrência de Passalora bougainvilleae (Muntañola) Castañeda & Braun associado à Bougainvillea spectabilis Willd. em Boa Vista, Roraima

    OpenAIRE

    Nechet,Kátia de Lima; Halfeld-Vieira,Bernardo A.

    2008-01-01

    O fungo Passalora bougainvilleae é relatado, pela primeira vez, na região de Boa Vista, Roraima, associado a manchas foliares na planta ornamental Bougainvillea spectabilis. As características do fungo são conidióforos agregados em fascículos, emergindo de um estroma subcuticular na face abaxial de lesões velhas. Os conidióforos são lisos, retos, de coloração marrom, não ramificados, maioria asseptados, medindo de 26-57µm x 4µm. Células conidiogênicas terminais de proliferação simpodial com c...

  7. Repot of Passalora bougainvilleae (Muntañola) Castañeda & Braun associated with Bougainvillea spectablis Willd. in Boa Vista, Roraima

    OpenAIRE

    Nechet, Kátia de Lima; Halfeld-Vieira, Bernardo A.

    2008-01-01

    O fungo Passalora bougainvilleae é relatado, pela primeira vez, na região de Boa Vista, Roraima, associado a manchas foliares na planta ornamental Bougainvillea spectabilis. As características do fungo são conidióforos agregados em fascículos, emergindo de um estroma subcuticular na face abaxial de lesões velhas. Os conidióforos são lisos, retos, de coloração marrom, não ramificados, maioria asseptados, medindo de 26-57µm x 4µm. Células conidiogênicas terminais de proliferação simpodial com c...

  8. A ringed fascia lata graft without peritendinous areolar tissue encircling the levator veli palatini and superior pharyngeal constrictor muscles gradually shrinks to reduce velopharyngeal incompetence, functioning as an intravelar palatal lift.

    Science.gov (United States)

    Fujita, Kenya; Matsuo, Kiyoshi; Yuzuriha, Shunsuke

    2013-01-01

    We have previously reported that fascia lata grafts with peritendinous areolar tissue used to treat severe congenital blepharoptosis gradually shrink within 6 weeks postoperatively and maintain long-term shrinkage of 15.5% on average. Accordingly, it seemed possible that a fascia lata graft without peritendinous areolar tissue would shrink more than the one with peritendinous areolar tissue in a clinical setting. We evaluated this possibility in a patient with Klippel-Feil syndrome having postoperative deep atonic nasopharynx. In combination with intravelar veloplasty and palatal lengthening with modified bilateral buccinator sandwich pushback, a ringed fascia lata without peritendinous areolar tissue encircling the levator veli palatini and superior constrictor muscles was grafted to cure severe velopharyngeal incompetence. Obstructive sleep apnea did not occur following surgery. Pharyngoscopy, videofluoroscopy, and nasometry showed no amelioration of velopharyngeal incompetence at 1 month postoperatively, but marked velopharyngeal incompetence reduction was evident at 4 months and 2 years after surgery. The extended recovery period suggests that the anticipated postoperative shrinkage of the ringed fascia lata without peritendinous areolar tissue played a more prominent role than intravelar veloplasty and palatal lengthening, which posteroinferiorly elongated the atonic soft palate. Although the pharyngeal flap procedure is the most popular technique for treatment of velopharyngeal incompetence, it is sometimes accompanied by respiratory complications. Thus, the gradual postoperative shrinkage of a ringed fascia lata graft encircling the velopharyngeal muscles functions as an intravelar palatal lift and may be an additional surgical method with less respiratory complications to narrow atonic nasopharyngeal port.

  9. Conhecimento dos moradores da comunidade de Boas Novas, no Lago Janauacá - Amazonas, sobre os hábitos alimentares dos peixes da região Regional fish diet knowledge of the Boas Novas community inhabitants on the lake Janauacá - Amazonas, Brazil

    Directory of Open Access Journals (Sweden)

    Alexandre Milaré Batistella

    2005-01-01

    Full Text Available A pesca na Amazônia é uma das atividades mais antigas e importantes; entretanto a atividade pesqueira tem passado por um rápido processo de modernização. Os moradores da comunidade de Boas Novas, no Lago do Janauacá AM são, em sua maioria, pescadores-lavradores. No presente trabalho procedeu-se um levantamento de aspectos etnoictiológicos através de entrevistas semi-estruturadas com o objetivo de relacionar a dieta das espécies de peixes citadas na literatura e pelos moradores da comunidade de Boas Novas e a forma com que adquiriram tal conhecimento. Houve correlação de 83% entre as informações dos pescadores e as encontradas na literatura. A maioria dos informantes adquiriu esse conhecimento através da observação na natureza, do tipo de isca que se usa para cada espécie, tratando os peixes ou informados por outras pessoas; havendo diferenças entre homens e mulheres.Fishing in Amazônia is one of the oldest and most important activities; however, fishing has undergone a rapid process of modernization. The formers inhabitants of Boas novas community on the Lake of Janauacá - AM are mostly fisherman. In the present work a recording of ethnoichthyologic aspects was conducted through semi-structured interviews aiming to relate the fish diet mentioned in the literature and by community's inhabitants of Boas Novas, and how they acquired such knowledge. There was a correlation of 83% between the fishermen information and the literature. Most of the informants acquired their knowledge through observing nature, bait type used for each species, fish with respect to this preparing or information received from other people; there are differences between men and women knowledge.

  10. Adenocarcinoma do pulmão – Até quando a boa resposta?

    Directory of Open Access Journals (Sweden)

    Maria José Simões

    2008-10-01

    Full Text Available Resumo: Relatase o caso de uma doente de 75 anos que em Out./2004 recorreu ao SU por queixas de tosse, febre e toracalgia esq. Com características pleuríticas. A semiologia pulmonar foi compatível com derrame pleural esq. E procedeu-se à respectiva investigação clínica. Existiam parâmetros de infecção elevados no contexto de um exsudado pleural. A tomografia computorizada evidenciou derrame pleural e espessamento no segmento anterior do LSD, cuja bronco-fibroscopia apenas visualizou alterações inflamatórias. Em Fev./2005 verifica-se recidiva do derrame pleural. A tomografia computorizada referia agora a existência de densificação nodular adjacente ao BLSE e língula. Em conjunto com a equipa de cirurgia torácica, foi decidido procederse a videoto-racoscopia. Durante a realização da técnica houve necessidade de conversão para toracotomia e o pós-operatório foi moroso. O exame histológico revelou um CPNPC – adenocarcinoma. A doente iniciou quimioterapia de primeira linha e em Mar./2006 sur-giu metastização óssea. Efectua quimioterapia de segunda linha, tendo-se mantido em doença estável, e em Jul./2007 inicia terapêutica com erlotinib que mantém actualmente, com boa tolerância, sem queixas álgicas e sem progressão da doença sob 13 meses de terapêutica. E até quando esta resposta?Rev Port Pneumol 2008; XIV (Supl 3: S71-S77 Abstract: A 75 year old woman was observed at the emergency department with cough, hyperthermia and thoracic pain in October 2004.A pleural effusion was identified and studied. Thorax CT scan evidenced a pleural effusion and thickening in the RSL anterior segment but bronchofibroscopy only identified inflammatory changes. In February 2005 the pleural effusion relapsed and the CT scan showed nodular densification adjacent to LSLB and lingual. VATS converted to thoracotomy was preformed and followed by a long

  11. Teores de Elementos Minerais e Caracterização Física da Uva Isabel (Vitis labrusca L. Produzida em Boa Vista/RR

    Directory of Open Access Journals (Sweden)

    Magda Márcia Becker

    2014-07-01

    Full Text Available The Roraima viticulture began in 2003 with the creation of the Vale do Rio Branco project, in which the cultivation of grapes was enlarged for a commercial production. However, no information has been found in literature  about the mineral content of grapes produced. Considering the essentiality and importance of this information for human nutrition, quantification of species K by flame photometry and Ca, Fe and Zn by flame atomic absorption spectrometry in pulps of grapes of the Isabel, Vitis labrusca L. variety, cultivated in Boa Vista/RR has been realized, as well as determination of the physical characteristics of the grape bunches and berries. The determinations´ results indicate that K had the highest concentration, followed by Ca, Fe and Zn, being similar to the data, described in other literature sources, except for Ca, which showed smaller, indicating an intervention demand of culture methods employed to optimize the absorption of this species by vines. The consumption of Isabel grape can contribute to the achievement of the adequate intake recommendations of mineral elements. The results of the physical characterization let us classify Isabel grape bunches to very small, loose and green stalks. Overall, this study reveals new data about the physical characteristics and mineral composition present in Isabel grape grown in Boa Vista/RR.

  12. Nicomachean Ethics VI.9: good deliberation and phronesis [Ética a Nicômaco VI.9: boa deliberação e phronesis

    Directory of Open Access Journals (Sweden)

    Angelo Antonio Pires de Oliveira

    2017-08-01

    Full Text Available In this paper, I put under scrutiny the arguments put forward by Aristotle in Nicomachean Ethics (NE VI.9. The paper has two main parts. In the first, I examine the NE VI.9’s first part where Aristotle develops the concept of good deliberation, offering its definition in 1142b27-28. In the second, I examine the connection between good deliberation and phronesis, and, then, discuss the vexata quæstio about if the lines 1142b31-33 might be read as introducing the claim that phronesis provides moral ends. [Neste artigo, analiso pormenorizadamente os argumentos apresentados por Aristóteles em Ética a Nicômaco (EN VI.9. O artigo é dividido em duas partes principais. Na primeira, abordo a primeira parte de EN VI.9 onde Aristóteles desenvolve a noção de boa deliberação, culminando com a apresentação da sua definição em 1142b27-28. Na segunda, abordo a conexão entre boa deliberação e phronesis e discuto a vexata quaestio de se as linhas 1142b31-33 podem ser lidas como introduzindo a tese de que a phronesis fornece os fins morais

  13. Beyond mean pharyngeal constrictor dose for beam path toxicity in non-target swallowing muscles: dose-volume correlates of chronic radiation-associated dysphagia (RAD) after oropharyngeal intensity modulated radiotherapy

    Science.gov (United States)

    2016-01-01

    Purpose/Objective(s) We sought to identify swallowing muscle dose-response thresholds associated with chronic radiation-associated dysphagia (RAD) after IMRT for oropharyngeal cancer. Materials/Methods T1-4 N0-3 M0 oropharyngeal cancer patients who received definitive IMRT and systemic therapy were examined. Chronic RAD was coded as any of the following ≥ 12 months post-IMRT: videofluoroscopy/endoscopy detected aspiration or stricture, gastrostomy tube and/or aspiration pneumonia. DICOM-RT plan data were autosegmented using a custom region-of-interest (ROI) library and included inferior, middle and superior constrictors (IPC, MPC, and SPC), medial and lateral pterygoids (MPM, LPM), anterior and posterior digastrics (ADM, PDM), intrinsic tongue muscles (ITM), mylo/geniohyoid complex (MHM), genioglossus (GGM), ), masseter (MM), Buccinator (BM), palatoglossus (PGM), and cricopharyngeus (CPM), with ROI dose-volume histograms (DVHs) calculated. Recursive partitioning analysis (RPA) was used to identify dose-volume effects associated with chronic-RAD, for use in a multivariate (MV) model. Results Of 300 patients, 34 (11%) had chronic-RAD. RPA showed DVH-derived MHM V69 (i.e. the volume receiving ≥69Gy), GGM V35, ADM V60, MPC V49, and SPC V70 were associated with chronic-RAD. A model including age in addition to MHM V69 as continuous variables was optimal among tested MV models (AUC 0.835). Conclusion In addition to SPCs, dose to MHM should be monitored and constrained, especially in older patients (>62-years), when feasible. PMID:26897515

  14. Beyond mean pharyngeal constrictor dose for beam path toxicity in non-target swallowing muscles: Dose-volume correlates of chronic radiation-associated dysphagia (RAD) after oropharyngeal intensity modulated radiotherapy.

    Science.gov (United States)

    2016-02-01

    We sought to identify swallowing muscle dose-response thresholds associated with chronic radiation-associated dysphagia (RAD) after IMRT for oropharyngeal cancer. T1-4 N0-3 M0 oropharyngeal cancer patients who received definitive IMRT and systemic therapy were examined. Chronic RAD was coded as any of the following ⩾12months post-IMRT: videofluoroscopy/endoscopy detected aspiration or stricture, gastrostomy tube and/or aspiration pneumonia. DICOM-RT plan data were autosegmented using a custom region-of-interest (ROI) library and included inferior, middle and superior constrictors (IPC, MPC, and SPC), medial and lateral pterygoids (MPM, LPM), anterior and posterior digastrics (ADM, PDM), intrinsic tongue muscles (ITM), mylo/geniohyoid complex (MHM), genioglossus (GGM), masseter (MM), buccinator (BM), palatoglossus (PGM), and cricopharyngeus (CPM), with ROI dose-volume histograms (DVHs) calculated. Recursive partitioning analysis (RPA) was used to identify dose-volume effects associated with chronic-RAD, for use in a multivariate (MV) model. Of 300 patients, 34 (11%) had chronic-RAD. RPA showed DVH-derived MHM V69 (i.e. the volume receiving⩾69Gy), GGM V35, ADM V60, MPC V49, and SPC V70 were associated with chronic-RAD. A model including age in addition to MHM V69 as continuous variables was optimal among tested MV models (AUC 0.835). In addition to SPCs, dose to MHM should be monitored and constrained, especially in older patients (>62-years), when feasible. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  15. Dysphagia disorders in patients with cancer of the oropharynx are significantly affected by the radiation therapy dose to the superior and middle constrictor muscle: A dose-effect relationship

    International Nuclear Information System (INIS)

    Levendag, Peter C.; Teguh, David N.; Voet, Peter; Est, Henri van der; Noever, Inge; Kruijf, Wilhelmus J.M. de; Kolkman-Deurloo, Inger-Karine; Prevost, Jean-Briac; Poll, Johan; Schmitz, Paul I.M.; Heijmen, Ben J.

    2007-01-01

    Purpose/Objective: To assess the relationship between the radiation therapy (RT) dose received by the muscular components of the swallowing (sw) apparatus and - dysphagia related - quality of life (QoL) in oropharyngeal cancer. Materials/Methods: Between 2000 and 2005, 81 patients with SCC of the oropharynx were treated by 3DCRT or IMRT, with or without concomitant chemotherapy (CHT); 43 out of these 81 patients were boosted by brachytherapy (BT). Charts of 81 patients were reviewed with regard to late dysphagia complaints; 23% experienced severe dysphagia. Seventeen patients expired. Fifty-six out of 64 (88%) responded to quality of life (QoL) questionnaires; that is, the Performance Status Scales of List, EORTC H and N35, and the M.D. Anderson Dysphagia Inventory. The superior (scm), middle (mcm), and inferior constrictor muscle (icm), the cricopharyngeus muscle and the inlet of the esophagus, are considered of paramount importance for swallowing. The mean dose was calculated in the muscular structures. Univariate analysis and multivariate analysis were performed using the proportional odds model. Results: Mean follow-up was 18 months (range 2-34) for IMRT, and 46 months for 3DCRT (range 2-72). At 3-years, a LRC of 84%, DFS of 78% and OS of 77% were observed. A significant correlation was observed between the mean dose in the scm and mcm, and severe dysphagia complaints (univariate analysis). A steep dose-effect relationship, with an increase of the probability of dysphagia of 19% with every additional 10 Gy, was established. In the multivariate analysis, BT (dose) was the only significant factor. Conclusion: A dose-effect relationship between dose and swallowing complaints was observed. One way to improve the QoL is to constrain the dose to be received by the swallowing muscles

  16. A Percepção dos Visitantes quanto as Informações Turísticas na Rodoviária Internacional de Boa Vista, RR

    Directory of Open Access Journals (Sweden)

    Rita Michelin

    2014-04-01

    Full Text Available Normal 0 false false false PT-BR JA X-NONE Considerando o Turismo como um fenômeno social de grande importância, a presente pesquisa teve por objetivo principal analisar a percepção dos visitantes acerca da hospitalidade pública de recepção na Rodoviária Internacional de Boa Vista (RBV, em Roraima, através da disponibilização de informações turísticas. Atualmente, a Rodoviária recebe um grande fluxo de visitantes, no entanto, não existe ali um local que preste as informações básicas quanto ao Turismo e aos serviços locais, para quem chega a cidade. Tendo por premissa que o viés da hospitalidade deve ser considerado desde o primeiro momento em que o visitante chega a um destino turístico, a hospitalidade pública representada pelas informações turística faz-se de fundamental importância para bem receber o turista e, consequentemente, levá-lo a perceber o município como um destino turístico hospitaleiro.Perception of visitors on the Tourist Office at the International Bus Station Boa Vista, RR - Considering tourism as a social phenomenon of great importance, the research objective was to analyze the perception of the visitors about public hospitality on International Bus Station of Boa Vista (RBV through the availability of tourist information. Currently the bus station receives a large number of visitors; however, there isn’t a place that provides basic information about the tourism and local services. Having premised that the hospitality must be considered from the first moment the visitor arrives at a destination, the public hospitality represented by the tourist information make it crucial for welcoming tourists and charm you aiming your satisfaction.

  17. Caracterização morfométrica da bacia hidrográfica do Igarapé Carrapato, Boa Vista, Roraima

    Directory of Open Access Journals (Sweden)

    Maola Monique Faria

    2017-10-01

    Full Text Available O manejo de bacias hidrográficas baseia-se em um conjunto de técnicas aplicadas com o objetivo de regularizar a vazão dos cursos hídricos, a produção econômica e a proteção ambiental, garantindo a preservação da biodiversidade. O presente estudo tem como objetivo determinar as características morfométricas da bacia hidrográfica do Igarapé Carrapato, Boa Vista/Roraima. Inicialmente foi obtido o Modelo Digital de Elevação, e com base nele a bacia foi delimitada. Posteriormente foram calculados alguns parâmetros morfométricos para o estudo do comportamento hidrológico da bacia. A bacia em estudo, com base na análise dos fatores morfométricos analisados, apresenta baixa susceptibilidade a enchentes.

  18. 嵌入式Linux Webserver软件BOA实现与应用%The Application and Realization of Embedded Linux WebServer BOA

    Institute of Scientific and Technical Information of China (English)

    骆懿; 章坚武

    2004-01-01

    介绍了一种嵌入式Webserver软件BOA在摩托罗拉公司生产的嵌入式CPU MPC823e上的应用.在嵌入式MPC823e平台上成功移植了Linux和BOA webserver.并实现了在串口与嵌入式网页之间交换数据的CGI网关程序.这种嵌入式WebSever方案可以广泛应用在许多实际的应用领域,如自动化设备的远程监控,嵌入式GSM短消息平台,远程家庭医疗等.

  19. 嵌入式Web服务器Boa的移植及其应用%Transplant of Embedded Web Server Boa and Its Application

    Institute of Scientific and Technical Information of China (English)

    陆永健; 王萍; 吴佳; 张永力

    2005-01-01

    鉴于目前监控系统对实时性和多连接处理能力的要求,介绍一款单任务的嵌入式Web服务器Boa.对将Boa移植到运行uClinux操作系统的ARM微处理器平台上的过程进行了讨论,在此基础上构建了嵌入式Web服务器,为用户提供基于HTTP协议的网络接入方式,最后给出一个基于B/S模式的网络视频监控系统的实例.

  20. Alterações na composição florística das algas da Praia de Boa Viagem (Niterói, RJ)

    OpenAIRE

    TAOUIL, ANDRÉ; YONESHIGUE-VALENTIN, YOCIE

    2002-01-01

    A Baía de Guanabara no decorrer da ocupação de suas margens sofreu uma continua degradação, levando-a a grandes modificações em seu entorno e a inúmeros danos ambientais. Além de uma significativa alteração paisagística, ocorreu também uma queda na qualidade de suas águas, devido ao lançamento de grande quantidade de efluentes não tratados (domésticos e industriais). Este trabalho teve como objetivo inventariar a flora algácea da praia de Boa Viagem (Niterói, RJ), compará-la com levantamentos...

  1. Prevalência de consumo alimentar entre hipertensos e diabéticos na cidade de Nova Boa Vista, Rio Grande do Sul, Brasil, 2013

    Directory of Open Access Journals (Sweden)

    Kelli Destri

    Full Text Available Resumo OBJETIVO: descrever o consumo alimentar em uma população de hipertensos e diabéticos de uma cidade do sul do Brasil. MÉTODOS: estudo transversal descritivo, realizado na cidade de Nova Boa Vista-RS, Brasil, entre junho e setembro de 2013; dados sobre consumo alimentar foram coletados utilizando-se o questionário do Sistema de Vigilância Alimentar e Nutricional (SISVAN, a adequação foi baseada no Guia Alimentar para a População Brasileira de 2008. RESULTADOS: foram incluídos 422 participantes (≥18 anos de idade; os alimentos que tiveram maior frequência de consumo recomendada foram salada crua (60,7%, frutas (73,0%, lácteos (61,4%, frituras (57,3%, salgados (66,4% e refrigerantes (76,3%; embutidos e doces foram os alimentos que tiveram maior frequência de consumo não recomendado, 34,8% e 23,9% respectivamente; a prevalência de consumo semanal recomendado de frutas foi 19% maior entre mulheres (p=0,004. CONCLUSÃO: o consumo alimentar na população do estudo parece estar de acordo com as frequências recomendadas, especialmente entre mulheres.

  2. 基于BOA网络与GPRS的智能家居监控系统%Smart Home Monitoring System Based on BOA Network and GPRS

    Institute of Scientific and Technical Information of China (English)

    王聪; 王鹏

    2011-01-01

    In this paper, a method for smart home control GPRS module through BOA web server is proposed, then system based on ARM 9 core S3C2440 and SIM300 the design method of the system hardware platform and the system software based on CGI is also represented, this system has feature of having higher HTTP request processing speed, it can realize high-speed and high-efficient home monitoring, it is valuable to other system's development based on embedded system and network.%提出了一种基于ARM9核心的S3C2440 CPU、SIM300 GPRS无线传输模块及BOA网络服务器的智能家居监控系统设计方案,给出了系统硬件平台的设计方案,搭建了BOA网络服务器,并编制了基于CGI规范集的系统软件.此设计方案具有较高的HTTP请求处理速度,可以实现高速、高效的家居监控,同时在其它基于嵌入式及网络平台的相关设计中也具有一定的参考价值.

  3. The Fdb3 transcription factor of the Fusarium Detoxification of Benzoxazolinone gene cluster is required for MBOA but not BOA degradation in Fusarium pseudograminearum.

    Science.gov (United States)

    Kettle, Andrew J; Carere, Jason; Batley, Jacqueline; Manners, John M; Kazan, Kemal; Gardiner, Donald M

    2016-03-01

    A number of cereals produce the benzoxazolinone class of phytoalexins. Fusarium species pathogenic towards these hosts can typically degrade these compounds via an aminophenol intermediate, and the ability to do so is encoded by a group of genes found in the Fusarium Detoxification of Benzoxazolinone (FDB) cluster. A zinc finger transcription factor encoded by one of the FDB cluster genes (FDB3) has been proposed to regulate the expression of other genes in the cluster and hence is potentially involved in benzoxazolinone degradation. Herein we show that Fdb3 is essential for the ability of Fusarium pseudograminearum to efficiently detoxify the predominant wheat benzoxazolinone, 6-methoxy-benzoxazolin-2-one (MBOA), but not benzoxazoline-2-one (BOA). Furthermore, additional genes thought to be part of the FDB gene cluster, based upon transcriptional response to benzoxazolinones, are regulated by Fdb3. However, deletion mutants for these latter genes remain capable of benzoxazolinone degradation, suggesting that they are not essential for this process. Crown Copyright © 2016. Published by Elsevier Inc. All rights reserved.

  4. Sex allocation and secondary sex ratio in Cuban boa ( Chilabothrus angulifer): mother's body size affects the ratio between sons and daughters

    Science.gov (United States)

    Frynta, Daniel; Vejvodová, Tereza; Šimková, Olga

    2016-06-01

    Secondary sex ratios of animals with genetically determined sex may considerably deviate from equality. These deviations may be attributed to several proximate and ultimate factors. Sex ratio theory explains some of them as strategic decisions of mothers improving their fitness by selective investment in sons or daughters, e.g. local resource competition hypothesis (LRC) suggests that philopatric females tend to produce litters with male-biased sex ratios to avoid future competition with their daughters. Until now, only little attention has been paid to examine predictions of sex ratio theory in snakes possessing genetic sex determination and exhibiting large variance in allocation of maternal investment. Cuban boa is an endemic viviparous snake producing large-bodied newborns (˜200 g). Extremely high maternal investment in each offspring increases importance of sex allocation. In a captive colony, we collected breeding records of 42 mothers, 62 litters and 306 newborns and examined secondary sex ratios (SR) and sexual size dimorphism (SSD) of newborns. None of the examined morphometric traits of neonates appeared sexually dimorphic. The sex ratio was slightly male biased (174 males versus 132 females) and litter sex ratio significantly decreased with female snout-vent length. We interpret this relationship as an additional support for LRC as competition between mothers and daughters increases with similarity of body sizes between competing snakes.

  5. Curso de Capacitação em Boas Práticas na Manipulação de Alimentos

    Directory of Open Access Journals (Sweden)

    Thaysa Bastos Bastos

    2014-12-01

    Full Text Available http://dx.doi.org/10.5007/1807-0221.2014v11n18p99 Objetivo: Descrever o treinamento utilizado no curso de capacitação em boas práticas na manipulação de alimentos. Método: A capacitação se deu através de treinamentos realizados para proprietários e funcionários de comércios no período de abril à setembro de 2012. As palestras ministradas tiveram 8 horas de duração, distribuídas em dois turnos vespertinos consecutivos (4 horas/dia uma vez ao mês. Resultados: Os conteúdos desenvolvidos estão de acordo com as normas regulamentadoras vigentes e dentre elas destacam-se a RDC 259, RDC 216, Portaria 2619, Lei 13725, Lei 14264, Portaria SVS/MS nº 326 e Orientações para os consumidores de saneantes. Conclusão: O treinamento de capacitação para manipuladores de alimentos foi essencial para agregar conhecimentos aos seus participantes.

  6. Evaluación de la eficiencia fotosintética del fitoplancton en un lago amazónico (Lago Boa y en un lago andino (Lago Guatavita Evaluation of the phytoplanktonic photosynthetic efficiency in an Amazon Lake (Lake Boa and in an Andean Lake (Lake Guatavita

    Directory of Open Access Journals (Sweden)

    Gabriel A. Pinilla

    2006-01-01

    Full Text Available La relación entre la fluorescencia variable y la fluorescencia máxima (Fv/Fm de las comunidades de algas se ha utilizado comúnmente como una medida de la eficiencia fotosintética del fitoplancton. Dicha eficiencia puede estar afectada por la localización de los ambientes acuáticos en distintas provincias limnológicas. En este trabajo se quiso establecer la diferencia en la relación Fv/Fm entre el lago Boa (150 msnm, Amazonía colombiana y el lago Guatavita (3000 msnm, cordillera oriental de los Andes colombianos. Los promedios de las eficiencias medidas fueron en general bajos (0,212 a 0,367 y 0,089 a 0,32 en los lagos Boa y Guatavita, respectivamente, lo que señala estrés fisiológico para las algas. La eficiencia fue mayor en aguas intermedias y presentó cambios fuertes entre épocas de muestreo y entre ecosistemas. En aguas superficiales se presentó fotoinhibición, la cual fue más fuerte en Guatavita. La eficiencia fotosintética fue menor en el lago andino debido posiblemente a diferencias climáticas, de altura sobre el nivel del mar y de estratificación. Durante los ensayos de laboratorio se observó que la eficiencia disminuyó con el tiempo, lo cual pudo deberse a una aclimatación de las algas a la oscuridad. Los datos de laboratorio confirmaron que el fitoplancton epilimnético del lago Guatavita estuvo fotoinhibido en la época de estratificación.Commonly relation between variable fluorescence and maximum fluorescence (Fv/Fm of the algae community has been utilized like a measure of the phytoplanktonic photosynthetic efficiency. Such efficiency can be affected by the water bodies' location in different limnological provinces. The goal of this work was to establish the differences in the Fv/Fm rate between Lake Boa (150 masl Colombian Amazon and Lake Guatavita (3000 masl, East Range in the Colombian Andes. In general, averages of the photosynthetic efficiencies were low (0.212 to 0.367 and 0.089 to 0.32 in lakes Boa and

  7. Ocorrência de Passalora bougainvilleae (Muntañola Castañeda & Braun associado à Bougainvillea spectabilis Willd. em Boa Vista, Roraima Repot of Passalora bougainvilleae (Muntañola Castañeda & Braun associated with Bougainvillea spectablis Willd. in Boa Vista, Roraima

    Directory of Open Access Journals (Sweden)

    Kátia de Lima Nechet

    2008-01-01

    Full Text Available O fungo Passalora bougainvilleae é relatado, pela primeira vez, na região de Boa Vista, Roraima, associado a manchas foliares na planta ornamental Bougainvillea spectabilis. As características do fungo são conidióforos agregados em fascículos, emergindo de um estroma subcuticular na face abaxial de lesões velhas. Os conidióforos são lisos, retos, de coloração marrom, não ramificados, maioria asseptados, medindo de 26-57µm x 4µm. Células conidiogênicas terminais de proliferação simpodial com cicatrizes escuras e pouco espessas. Os conídios são solitários, marrom claro, obclavados, retos a ligeiramente curvos, medindo de 32-70 µm x 4-5 µm, maioria com 3 septos, apresentando um hilo truncado e ápice obtuso.The fungi Passalora bougainvilleae is reported, for the first time, Boa Vista, Roraima state, causing leaf spots on ornamental specie Bougainvillea spectabilis. The fungi characteristics are conidiophores hypophyllous in fascicles arising from the upper cells of a stroma subcuticular at old spots. The conidiphores are smooth, straight, pale brown, non-branched, mostly aseptate, 26-57µm x 4µm. Conidiogenous cells terminal, sympodial with black and thin scars. Conidia solitary, pale brown, obclavate, straight to slightly flexuous, 32-70 µm x 4-5 µm, 3 septate, rounded at apex, truncate at base, with a conspicuous hilum.

  8. Genetic divergence and diversity in the Mona and Virgin Islands Boas, Chilabothrus monensis (Epicrates monensis) (Serpentes: Boidae), West Indian snakes of special conservation concern.

    Science.gov (United States)

    Rodríguez-Robles, Javier A; Jezkova, Tereza; Fujita, Matthew K; Tolson, Peter J; García, Miguel A

    2015-07-01

    Habitat fragmentation reduces the extent and connectivity of suitable habitats, and can lead to changes in population genetic structure. Limited gene flow among isolated demes can result in increased genetic divergence among populations, and decreased genetic diversity within demes. We assessed patterns of genetic variation in the Caribbean boa Chilabothrus monensis (Epicrates monensis) using two mitochondrial and seven nuclear markers, and relying on the largest number of specimens of these snakes examined to date. Two disjunct subspecies of C. monensis are recognized: the threatened C. m. monensis, endemic to Mona Island, and the rare and endangered C. m. granti, which occurs on various islands of the Puerto Rican Bank. Mitochondrial and nuclear markers revealed unambiguous genetic differences between the taxa, and coalescent species delimitation methods indicated that these snakes likely are different evolutionary lineages, which we recognize at the species level, C. monensis and C. granti. All examined loci in C. monensis (sensu stricto) are monomorphic, which may indicate a recent bottleneck event. Each population of C. granti exclusively contains private mtDNA haplotypes, but five of the seven nuclear genes assayed are monomorphic, and nucleotide diversity is low in the two remaining markers. The faster pace of evolution of mtDNA possibly reflects the present-day isolation of populations of C. granti, whereas the slower substitution rate of nuDNA may instead mirror the relatively recent episodes of connectivity among the populations facilitated by the lower sea level during the Pleistocene. The small degree of overall genetic variation in C. granti suggests that demes of this snake could be managed as a single unit, a practice that would significantly increase their effective population size. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. ANÁLISE DOS CICLOS DE PRECIPITAÇÃO NA REGIÃO DE BOA VISTA - RR NOS ANOS DE 1910 A 2014

    Directory of Open Access Journals (Sweden)

    Danielle Alves Silva

    2015-12-01

    Full Text Available Este estudo buscou relacionar e identificar a influência dos fenômenos ENOS nos índices de precipitação da série histórica (1910 a 2014 da estação pluviométrica de Boa Vista, Capital do Estado de Roraima, Brasil. Os procedimentos metodológicos compreenderam: a análises estatísticas dos dados diários, mensais e anuais para definição da série pluviométrica identificação de diferentes ciclos pluviométricos; b identificação e confrontação dos dados pluviométricos com os períodos de vigência dos fenômenos ENOS (El Niño e La Niña a fim de identificar relações destes com anomalias observadas na série histórica. A análise da série histórica permitiu a identificação de quatro ciclos pluviométricos, representados por dois ciclos secos e outros dois úmidos. Os eventos ENOS (El Niño e La Niña apresentaram grande compatibilidade com as variações pluviométricas da série. Os resultados apontam para a necessidade do estado e da sociedade civil se organizar aos efeitos dos ciclos de El Niño, em especial a retração do volume superficial de água disponível, estações secas mais fortes e ampliação de eventos de queimadas e, no caso dos ciclos de  La Niña, recorrência de cheias e eventos associados.

  10. PROPOSTA DE PLANO DE EDUCAÇÃO TECNOLÓGICA PARA AS ESCOLAS DE ENSINO FUNDAMENTAL DO MUNICÍPIO DE BOA VIAGEM CEARÁ

    Directory of Open Access Journals (Sweden)

    Mariana Pereira Silva

    2018-04-01

    Full Text Available O artigo em questão foi elaborado abordando o uso da tecnologia na sala de aula, baseando-se nas habilidades definidas no documento de referências de formação em computação para educação básica da Sociedade Brasileira de Computação - SBC. Este trabalho teve como objetivo a criação de um plano de educação tecnológica para educação básica, capaz de auxiliar os alunos no desenvolvimento de habilidades computacionais, adquiridas no desenvolvimento de atividades de informática, matemática e inglês usando ferramentas digitais. A pesquisa aconteceu em uma escola de ensino fundamental no município de Boa Viagem. Durante a pesquisa foi ofertado curso de informática em horário extracurricular quando abordou-se desde conceitos de computação, incluindo manutenção de computadores, segurança da informação e programação. Em paralelo trabalhou-se com os professores o uso de ferramentas como Khan Academy e Duolingo. Conclui-se que ao utilizar o computador nas aulas de matemática e inglês, os alunos demonstraram forte interesse em realizar as atividades, mantendo o foco e melhor assimilação dos conteúdos. Com a pesquisa bibliográfica e a experiência na escola, foi possível perceber as vantagens em incluir no currículo escolar, disciplinas ou componentes que contribuam com o desenvolvimento de competências digitais, mas ainda há um grande caminho a ser percorrido no que se refere a infraestrutura e formação de professores.

  11. Impacto econômico da implantação das boas práticas agropecuárias relacionadas com a qualidade do leite

    Directory of Open Access Journals (Sweden)

    Marcel Gomes Paixão

    2014-10-01

    Full Text Available Objetivou-se, neste estudo, avaliar o impacto econômico da implantação das boas práticas agropecuárias (BPA, relacionadas com a qualidade higiênica sanitária do leite. A pesquisa consistiu na simulação de nove cenários, compostos por três diferentes níveis de BPA para a melhoria da qualidade do leite (baixo, médio e alto, em três diferentes situações (somente aplicação das BPAs; aplicação das BPAs e construção da sala do leite; e aplicação das BPAs, construção da sala do leite e aquisição do tanque de expansão. O rebanho leiteiro hipotético constava de 30 vacas em lactação, com média de dez litros de leite/animal/dia, ordenhadas duas vezes ao dia, em ordenhadeira tipo "balde ao pé". A receita consistiu na média da bonificação/penalização, praticadas por dez laticínios da região sudeste, considerando-se diferentes intervalos de contagem de células somáticas (CCS e contagem bacteriana total (CBT. A inclusão das BPAs para a melhoria da qualidade do leite, quando praticadas em seu nível máximo, mostrou-se com rápido retorno do capital investido (payback e ótima taxa interna de retorno (TIR apenas para aqueles pecuaristas que já possuíam a sala do leite e o tanque de expansão.

  12. Composição florística e fitossociologia do cerrado sentido restrito no município de Água Boa - MT

    Directory of Open Access Journals (Sweden)

    Felfili Jeanine Maria

    2002-01-01

    Full Text Available O estudo foi conduzido no município de Água Boa , no Vale do Araguaia, área de ecótono entre o Cerrado e Amazônia, que apresenta um complexo vegetacional com o predomínio do cerrado. O objetivo deste trabalho foi estudar a composição florística e a fitossociologia do cerrado sentido restrito na região. Foram alocadas dez parcelas de 20x50m (1000m². Entraram na amostragem todos os indivíduos lenhosos com diâmetro no nível do solo igual ou superior a 5cm. Além da amostragem com identificação in loco das espécies, foram efetuadas incursões de coleta em áreas próximas, para ampliar o levantamento da composição florística. Foram encontradas 34 famílias botânicas, contendo 60 gêneros e 80 espécies. A família Leguminosae apresentou o maior número de espécies (10, seguida por Myrtaceae (7, Vochysiaceae (6 e Malpighiaceae (5. Outras 19 famílias foram representadas por uma única espécie. As espécies com maior Índice de Valor de Importância foram Curatella americana L., Qualea parviflora Mart., Callisthene fasciculata Mart., Mezilaurus crassiramea (Meiss Taub. e Byrsonima crassa Nied. Treze espécies estiveram representadas por um único indivíduo. A densidade foi de 995 indivíduos/ha e a área basal de 7,5 m² /ha. O índice de Shannon encontrado (H' foi de 3,69, evidenciando a alta diversidade da área.

  13. "Roda Boa", "Roda Boa": Legitimate Peripheral Participation in Diasporic "Capoeira"

    Science.gov (United States)

    Stephens, Neil; Delamont, Sara

    2010-01-01

    "Capoeira", the Brazilian dance and martial art, is taught across the world. Learners acquire vital knowledge and are socialised as "capoeiristas" through legitimate peripheral participation, in particular when watching games in the "roda". The "roda", the circle within which the "capoeira" game is played, is a classic place for learning by…

  14. Prevalência das ametropias e oftalmopatias em crianças pré-escolares e escolares em favelas do Alto da Boa Vista, Rio de Janeiro, Brasil Prevalence of the ametropias and eye diseases in preschool and school children of Alto da Boa Vista favelas, Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Abelardo de Souza Couto Júnior

    2007-10-01

    Full Text Available OBJETIVO: Estabelecer a prevalência das ametropias e oftalmopatias, no ano de 2001, em população pré-escolar e escolar de favelas do Alto da Boa Vista, Rio de Janeiro, Brasil. MÉTODOS: Estudo observacional do tipo transversal, durante campanha de saúde ocular na rede pública de ensino. Crianças com acuidade visual inferior a 0,8 ou com anormalidades foram triadas por voluntários treinados para serem avaliadas por oftalmologistas no Instituto Benjamin Constant. RESULTADOS: Foram avaliadas 1800 crianças no total. Destas, 306 (17,00 % do total foram encaminhadas ao IBC. Houve 183 (10,17% do total e 59,80% das triadas que receberam alta por apresentarem visão melhor que 0,8. A prevalência dos erros refrativos foi de 3,50% (ametropias positivas , 1,78%; ametropias negativas, 1,06% e astigmatismos mistos, 0,67%. A prevalência das oftalmopatias foi de 4,83%. (ambliopia teve prevalência de 2,00%, manifestações do estrabismo, 1,72% e outras causas 1,11%. CONCLUSÃO: Demonstrou-se a prevalência dos principais distúrbios oftalmológicos infantis nas favelas do Alto da Boa Vista e ressaltou-se a necessidade de campanhas para bom êxito no desenvolvimento da acuidade visual das crianças.PURPOSE: To estabilish the prevalence of the ametropias and eye diseases, in the year 2001, within a preschool and school population in Alto da Boa Vista favelas (slum, in the city of Rio de Janeiro, Brazil. METHODS: Transversal observational study during an ocular health campaign in public education schools. The children that have shown visual acuity fewer than 0.8 or abnormally were referred by trained volunteers to avaliation by ophthalmologists from the Benjamin Constant Institute. RESULTS: From the 1800 children who were examined, 306 (17.00% were referred to the ophthalmologic examination. There were 183 children (10.17% from total and 59.80% from referred that were dismissed for presenting visual acuity better than 0.8. The refractive errors

  15. BOA: Framework for Automated Builds

    CERN Document Server

    Ratnikova, N

    2003-01-01

    Managing large-scale software products is a complex software engineering task. The automation of the software development, release and distribution process is most beneficial in the large collaborations, where the big number of developers, multiple platforms and distributed environment are typical factors. This paper describes Build and Output Analyzer framework and its components that have been developed in CMS to facilitate software maintenance and improve software quality. The system allows to generate, control and analyze various types of automated software builds and tests, such as regular rebuilds of the development code, software integration for releases and installation of the existing versions.

  16. Feather Boas in Real Analysis

    Science.gov (United States)

    Barnes, Julie

    2011-01-01

    Several years ago, the author noticed that her students were having trouble understanding the formal definitions for convergence of sequences, continuity of functions, and uniform convergence of functions. To her students, these definitions were just a bunch of symbols with little to no meaning. She drew diagrams, but students had trouble seeing…

  17. BOA: Framework for automated builds

    International Nuclear Information System (INIS)

    Ratnikova, N.

    2003-01-01

    Managing large-scale software products is a complex software engineering task. The automation of the software development, release and distribution process is most beneficial in the large collaborations, where the big number of developers, multiple platforms and distributed environment are typical factors. This paper describes Build and Output Analyzer framework and its components that have been developed in CMS to facilitate software maintenance and improve software quality. The system allows to generate, control and analyze various types of automated software builds and tests, such as regular rebuilds of the development code, software integration for releases and installation of the existing versions

  18. AVALIAÇÃO DAS CONDIÇÕES HIGIÊNICO-SANITÁRIAS E DE BOAS PRÁTICAS DE FABRICAÇÃO EM PANIFICADORAS

    Directory of Open Access Journals (Sweden)

    Maria Fernanda CARDOSO

    2011-04-01

    Full Text Available As padarias ou panifi cadoras se difundiram no Brasil a partir da colonização, quando portugueses e espanhóis trouxeram hábitos alimentares da Europa, tornando-se parte da nossa história e cultura. Hoje as padarias estão deixando de ser apenas estabelecimentos responsá- veis pela fabricação artesanal e venda de pães, e estão se transformando em centros de convivência, gastronomia e serviços. Com o crescimento populacional em algumas cidades, as pessoas buscam sempre formas mais práticas para se alimentar e também com menor custo, ocasionando vários problemas de intoxicação e infecção alimentar devido a alimentos preparados. Assim, o presente trabalho teve por objetivo avaliar as condições higiênico-sanitárias de três panifi cadoras a partir da aplicação de uma lista de verifi cação e análise microbiológica das superfícies dos equipamentos. Pelos itens avaliados, a panifi cadora B foi a que mais apresentou conformidade aos itens analisados (91,7%, seguida pela panifi cadora A (86,7% e por último a panifi cadora C (83,3%. Concluiu-se que as panifi cadoras encontravam-se em condições higiênico-sanitárias inadequadas. Desta forma foi elaborado um material informativo para incentivar a adoção de medidas corretivas para higiene dos manipuladores e melhor higienização/sanitização dos equipamentos. O comprometimento de todos os envolvidos na produção de panifi cados é uma condição básica para o sucesso da implantação das boas práticas de fabricação e higienização no local de trabalho.

  19. As boas práticas de fabricação de medicamentos e suas determinantes | Good manufacturing practices of medicines and their determinants

    Directory of Open Access Journals (Sweden)

    Marcelo Vogler

    2017-05-01

    Full Text Available As Boas Práticas de Fabricação (BPF garantem que os medicamentos sejam consistentemente produzidos e controlados de acordo com padrões de qualidade previamente estabelecidos. Têm por objetivo gerenciar e minimizar os riscos inerentes à fabricação de medicamentos com vista a garantir a qualidade, eficácia e segurança do produto acabado. Desde o seu surgimento da forma como conhecemos hoje, várias versões se sucederam no Brasil e no mundo. Esse trabalho se propõe a analisar as BPF, por meio da análise de conteúdo dos marcos regulatórios brasileiros, identificando as determinantes que podem explicar a sua evolução através das últimas décadas. As BPF foram decompostas em temas e subtemas e suas versões, presentes nos cinco marcos regulatórios estudados, foram avaliadas. Foi possível comprovar, na evolução dos requisitos de fabricação de medicamentos, a interferência da inovação tecnológica e a influência de novas práticas relacionadas à qualidade, identificando, dessa forma, a dinâmica de transformação das BPF. ==================================================Good Manufacturing Practices (GMP ensure that drugs are consistently produced and controlled according to previously established quality standards. They are designed to manage and minimize the inherent risks involved in the manufacture of drugs in order to ensure the quality, efficacy and safety of the finished product. Since their inception as we know them today, several versions have taken place in Brazil and worldwide. This work proposes to analyze GMP, through the analysis of the content of Brazilian regulatory frameworks, identifying the determinants that can explain their evolution over the last decades. GMP were broken down into topics and subtopics and their versions present in the five regulatory frameworks studied were evaluated. It was possible to verify, in the evolution of drug manufacturing requirements, the interference of technological

  20. Efetividade da rede de atenção à saúde e à assistência social à pessoa idosa na expressão de usuários e gestores: o caso de Boa Vista/RR = Effectiveness of assistance and health social net of elders persons in the users and administrators expressions in Boa Vista/RR

    Directory of Open Access Journals (Sweden)

    Faleiros, Vicente de Paula

    2011-01-01

    Full Text Available Este artigo trata do paradigma e da efetivação da rede de proteção à pessoa idosa nas áreas de Assistência Social e Saúde, numa perspectiva crítica, tendo como referência a cidade de Boa Vista, capital do Estado de Roraima. A rede de proteção é definida como uma mediação de forças e de poder que se pactua, atuando formal ou informalmente. Salienta-se que os direitos sociais previstos na legislação devem ser efetivados numa rede de proteção. A metodologia da pesquisa consistiu de entrevistas semiestruturadas com duas gestoras da área da Saúde e uma da área de Assistência Social e de quatro grupos focais (dois de cada área com pessoas idosas, além de um mapa de serviços e de seus vínculos no território. Os resultados mostram que a mediação da proteção em redes se faz com pouca interatividade institucional pactuada e apenas informalmente, por meio de contatos, embora se reconheça um paradigma de ação integrada

  1. Política e cinema na era da Boa Vizinhança (1933-1945 * Policy and cinema at the age of the Good Neighbor (1933-1945

    Directory of Open Access Journals (Sweden)

    ISAIAS ALBERTIN DE MORAES

    2015-03-01

    Full Text Available Resumo: O presente artigo apresenta uma análise histórica da Política Externa de Boa Vizinhança para América Latina, particularmente no Brasil, e de sua principal instituição o Office of the coordinator of Inter-American Affairs (OCIAA, destacando sua divisão de cinema, a Motion Picture Division (MPD. Essas instituições são analisadas pelo enfoque teórico dos construtivistas modernistas-linguistas. Assim, o texto busca destacar a importância da construção de uma infraestrutura física, discursiva e humana com habilidade para selecionar, organizar, regular e redistribuir os discursos enunciados pela Política Externa de Boa Vizinhança no setor da indústria cinematográfica.Palavras-chave: Política Externa de Boa Vizinhança; Office of the coordinator of Inter-American Affairs; Motion Picture Division.  Abstract: This paper presents a historical analysis of the Good Neighbor Policy for Latin America, particularly in Brazil, and its main institution the Office of the coordinator of Inter-American Affairs (OCIAA, focusing on its film department, the Motion Picture Division (MPD. These institutions are analyzed by the theoretical approach of modernist linguists constructivists. So this text sought to highlight the importance of building a physical infrastructure, discursive and human with the ability to select, organize, regulate and redistribute the speeches set out by the Good Neighbor Policy in the film industry sector.Keywords: Good Neighbor Policy; Office of the coordinator of Inter-American Affairs; Motion Picture Division.

  2. A reaserch and implementation of embedded remote video monitoring system based on Boa web server%基于boa的嵌入式视频监控系统的研究与实现

    Institute of Scientific and Technical Information of China (English)

    翁彬彬; 徐塞虹

    2014-01-01

    This paper introduces the design and implementation of an embedded video monitoring system based on BOA web server, first expounds the overall structure and the work flow of the system,and the main function modules which will be realized, then respectively introduce the module of BOA web server and the module of PTZ control and presetmo-dule in detail, introduces the realization principle and working process of Boa web server, and how to transplant into the embedded system; introduces the design and the working process of PTZ control and preset module. The design scheme of the system integrate of the embedded technology and network technology, and it has reliable performance and perfect function, compared with the traditional video monitoring system has many advantages. It can be very good application in video monitoring and has important practical application value.%本文介绍了一种基于BOA网络服务器的嵌入式视频监控系统设计与实现,首先主要阐述了该系统的整体结构及工作流程,及其主要将要实现的功能模块,然后针对系统下两大模块BOA web 服务器模块和云台控制与预置位模块分别进行了较为详细的介绍,分别介绍了BOA网络服务器实现原理、工作流程,以及移植到嵌入式系统;云台控制与预置位模块的设计及其工作流程实现。该系统设计方案融合了嵌入式技术网络技术,功能可靠完善,性能与传统视频监控系统相比具有较大的优势,能够很好的应用在视频监控中,具有重要的实际应用价值。

  3. Oficinas de boas práticas de fabricação: construindo estratégias para garantir a segurança alimentar Workshops for good manufacturing practices: building strategies for ensuring food security

    Directory of Open Access Journals (Sweden)

    Tarcisio da Silva Costa

    2012-05-01

    Full Text Available A comercialização de alimentos tradicionais resgata a história e a cultura presentes nos alimentos. Os pescadores artesanais são os principais responsáveis pelo abastecimento do mercado nacional. Considerando-se a importância da adoção de procedimentos de Boas Práticas de Fabricação em toda cadeia produtiva, o presente trabalho visa a socializar uma experiência construtiva de uma oficina de Boas Práticas de Fabricação para pescadoras. Diante disso, realizou-se um levantamento de conceitos e atitudes voltadas para produção segura de alimentos, utilizando-se como instrumento entrevistas, além da observação de seus hábitos e atitudes. Os resultados evidenciam que estas pescadoras percebem as Boas Práticas de Fabricação como sinônimo de higiene e de poder comercializar o pescado sem reclamações; porém, as mesmas não têm noção dos procedimentos de Boas Práticas de Fabricação na sua atividade. O processo formativo se constitui como uma das estratégias de base para consolidação dos grupos, sendo as oficinas alternativas eficientes, de fácil execução e baixo custo.The marketing of traditional foods recalls the history and culture in feeding. The fishermen are primarily responsible for supplying the domestic market. Considering the importance of adopting procedures for Good Manufacturing Practices throughout the production chain, this paper aims to socialize a constructive experience of a Good Manufacturing Practices workshop for fishers. Therefore, we carried out a survey of concepts and attitudes towards safe food production, using interviews as an instrument, and are observed their habits and attitudes. The results show that these Good Manufacturing Practices perceive as synonymous with health and able to market the fish without complaint, but they are not aware of the procedures for Good Manufacturing Practices activities. The training process is constituted as one of the basic strategies for strengthening

  4. Vida privada de um homem público na década de 1950: uma liderança petebista na cidade de São João da Boa Vista, São Paulo

    OpenAIRE

    Nicolau, Maria

    2013-01-01

    A presente pesquisa analisa a emergência de um líder petebista no Município de São João da Boa Vista (SP), durante os anos de 1950. De nome Miguel Jorge Nicolau, oriundo de uma família de imigrantes árabe-libanesa, iniciou sua trajetória na vida pública a partir de seu quotidiano em uma fábrica têxtil da cidade (Fiatece), cujos trabalhadores eram fundamentalmente mulheres. Apesar da comunidade árabe-libanesa ser vista com certas reservas por parte daquela população interiorana, a que se acres...

  5. Catolicismo popular e poder simbólico: Narrativas e representações sobre Frei Francisco de Monte São Vítor em Boa Vista–GO (1841-1859

    Directory of Open Access Journals (Sweden)

    Euclides Antunes Medeiros

    2014-05-01

    Full Text Available O objetivo desse artigo é problematizar, dentro das relações sociais de poder, as práticas simbólicas que orientavam a religiosidade vinculada às legitimações de poder na cidade de Boa Vista, extremo norte de Goiás, entre as décadas de 1840 e 1860. O simbolismo religioso, expresso em rituais de fé e de submissão, permeado por um catolicismo popular, articula-se às demandas de dominação política e econômica, típicas das práticas de mandonismo e de coronelismo brasileiro. Tal simbolismo, ainda, constrói uma economia de trocas simbólicas das quais surgem sofisticadas estratégias de dominação, resistência e negociação entre religiosos, coronéis e sertanejos. A realidade em Boa Vista entre as décadas de 1840 e 1860 foi um jogo em que política e religiosidade constituíram campos de poder nos quis as fronteiras do sagrado e do profano constituíam a arena privilegiada de atuação de Frei Francisco de Monte São Vitor.

  6. Phytosanitary diagnostic and practices associated with pesticide use in gardens in a protected environment in the city of Boa Vista in Roraima. = Diagnóstico fitossanitário e de práticas associadas ao uso de agrotóxicos nas hortas em ambiente protegido em Boa Vista - Roraima.

    Directory of Open Access Journals (Sweden)

    Antonio Cesar Silva Lima

    2011-08-01

    Full Text Available The objective of this study was to diagnose pests, diseases, weeds, and practices associated with the use of agrochemicals on the production of vegetables under protected conditions in Boa Vista, Roraima, Brazil. The descriptive study was conducted in urban and rural areas during February to April 2008, in the gardens monitored by Project Greenhouse, administered by the Municipal Development agricultural Secretary of the City. The data collection instrument was a semistructured questionnaire with 50 questions, applied in situ without notice to 75 farmers (47% of the population under study.Data were analyzed by descriptive statistics. After analyzing the data it was found that the whitefly, aphids, thrips and caterpillars were the insect pests that needed to be better controlled. The principal diseases were blight and leaf blight. Significant weed pests originated from the species of the families Poaceae, Cyperaceae, Amaranthaceae, and Portulacaeae. Relative to the use of pesticides, the results showed that 68% of farmers used insecticides, 24% fungicides, and 8% herbicides; 92% indicated that they had received some kind of technical guidance and 41.3% seek the technical assistance in order to acquire a pesticide. Therefore, we conclude that there is a high incidence of problems in plant vegetable gardens, intensive use of pesticides, a variety of formulations of insecticides, fungicides and herbicides associated with the adoption of practices and attitudes of risk for farmers, which can aggravate the direct and indirect problems of intoxication, and cause contamination to the environment. =Objetivou-se com esse trabalho fazer o diagnóstico das pragas, doenças, plantas daninhas e das práticas associadas ao uso dos agrotóxicos utilizados na produção de hortaliças, em ambiente protegido, no município de Boa Vista, Roraima. O estudo descritivo foi realizado em área urbana e rural, nos meses de fevereiro a abril de 2008, nas hortas atendidas

  7. Avaliação de água de poços tubulares para consumo humano no Município de Boa Vista, Paraíba

    Directory of Open Access Journals (Sweden)

    Débora Samara Cruz Rocha Farias

    2016-12-01

    Full Text Available Na Região do Semiárido nordestino a diminuição da disponibilidade dos recursos hídricos superficiais tem levado a população da zona rural a buscar, nos recursos hídricos subterrâneos, a solução de seus problemas de abastecimento, o que tem acarretado um crescimento no número de perfurações de poços tubulares profundos. O trabalho objetivou avaliar a qualidade de águas utilizadas para consumo humano em áreas rurais da região de Boa Vista, Paraíba. As amostras de água foram coletadas em poços tubulares, em dois períodos: 4º trimestre de 2014 e 2º trimestre de 2015. As variáveis avaliadas foram: pH, CE, Ca, Mg, Na, K, HCO3 -, Cl, alcalinidade e dureza total e SDT. Das águas analisadas 94,55% são consideradas salgadas nas duas amostragens. Em sua maioria os teores de dureza, alcalinidade, cloreto, magnésio, sódio e potássio estão fora do limite estabelecido pela Portaria vigente no país. Com relação ao pH, as amostras se encontram dentro do padrão normal.Water quality for human consumption in rural communities in the municipality of Boa Vista, state ParaíbaAbstract: In the semi-arid northeastern region of decreasing availability of surface water resources has led to population from the countryside to look for underground water resources to solve their supply problems, which has led to an increase in the number of deep wells drilling. The study aimed to assess the quality of water used for human consumption in rural areas of the region Boa Vista, Paraíba. Water samples were collected from wells in two periods: 4th quarter 2014 and 2nd quarter of 2015. The variables evaluated were: pH, EC, Ca, Mg, Na, K, HCO3-, Cl, alkalinity and total hardness and TDS. 94.55% of the analyzed waters are considered cured in the two sampling. Mostly hardness levels, alkalinity, chloride, magnesium, sodium, potassium are beyond the limit set by current Ordinance in the country. Regarding the pH samples are within the normal pattern.

  8. A boa-fé nos contratos relacionais : análise da solução cooperativa para a preservação do equilíbrio nos contratos bancários

    OpenAIRE

    Pessoa, Carlos Levi Costa

    2013-01-01

    Aplicação da teoria relacional e as soluções cooperativas para a preservação do equilíbrio nos contratos bancários. A pesquisa visa a analisar a teoria relacional, demonstrando a interação entre o princípio da boa-fé e as soluções cooperativas para harmonização dos conflitos nos contratos de longa duração. A partir de estudos dessa doutrina estrangeira, pretende-se evidenciar as novas técnicas negociais adotadas nas relações bancárias de consumo, mais aptas a atender às atuais transformações ...

  9. Aplicação do sistema de gestão da qualidade das boas práticas de fabricação (bpf) no Brasil em empresas em produtos para a saúde.

    OpenAIRE

    Zotelli, Maroá Schaaf

    2012-01-01

    O sistema da qualidade atrelado a certificação nas Boas Práticas de Fabricação é exigido pela Agencia Nacional de Vigilância Sanitária (ANVISA) para garantir a segurança, a qualidade e a eficácia dos produtos médicos através da padronização dos processos, para todos os fabricantes ou distribuidores de produtos para a saúde que atuem em mercado brasileiro. Com o crescimento da produção de produtos para à saúde, o setor regulado parece enfrentar problemas referentes a morosidade ...

  10. ATRIBUTOS E PAPÉIS DOS COMITÊS DE AUDITORIA NA IMPLEMENTAÇÃO DAS BOAS PRÁTICAS DE GOVERNANÇA CORPORATIVA EM INSTITUIÇÕES FINANCEIRAS BRASILEIRAS

    Directory of Open Access Journals (Sweden)

    Patrícia Bernardes

    2008-09-01

    Full Text Available O objetivo deste trabalho é investigar, segundo as perspectivas dos Chief Financial Officer (CFO, Relações com Investidores (RI e Auditoria Interna (AI, a importância dos comitês de auditoria na implementação das melhores práticas de Governança Corporativa (GC em instituições financeiras brasileiras com ações ou títulos negociados no mercado de capitais norte-americano. Este texto, de caráter qualitativo, se fundamentou na teoria denominada Nova Economia Institucional, e utilizou como instrumento de pesquisa entrevistas realizadas com seis dirigentes, detentores das funções acima especificadas em duas instituições financeiras brasileiras de grande porte. Os resultados apurados indicam que as instituições financeiras pesquisadas possuem comitês de auditoria consolidados, que atuam como guardiões das boas práticas de GC

  11. TESTICULAR AND EPIDIDYMAL HISTOPATHOLOGICAL EVALUATION IN MONGREL ADULT DOGS FROM SÃO JOÃO DA BOA VISTA (SP REGION AVALIAÇÃO HISTOPATOLÓGICA TESTICULAR E EPIDIDIMÁRIA EM CÃES ADULTOS SEM RAÇA DEFINIDA (SRD DA REGIÃO DE SÃO JOÃO DA BOA VISTA, SP

    Directory of Open Access Journals (Sweden)

    Renée Laufer Amorim

    2007-12-01

    Full Text Available

    Little has been explored about testicular and epidi-dymal changes in dogs in different Brazilian regions and their influence on canine fertility, mainly in mongrel dogs. This study was performed to verify the prevalence of testicular and epididymal histopathological changes in mongrel adult dogs from São João da Boa Vista (SP region, as well as the frequency according to animal size and occurrence of simultaneous testicular and epididymal lesions. The use of mongrel dogs was based on the fact that it is the most common breed in the Brazilian canine popula-tion. Testicles and epipidymis were obtained from 60 adult dogs, between 3 and 6 years old, in castration campaign and sorted to in small breed (28 animals, medium breed (28 animals and large breed (14 animals. Histopathological evaluation of the 120 testicles showed 107 cases of degeneration, 89 of tubular atrophy, 16 of hipoplasia, 6 of orchitis, 3 leydig cell tumor, 2 normal tissue, one sertolli cell tumor and one case of edema. In the epididymal evaluation, 55 were considered normal, 36 inflammatory, 22 papillary hyperplasia, 14 degenerations, 12 cribriform hyperplasia, 3 cases of fibrosis, one edema, one adeno-miosis and one spermatic granuloma. Testicular and epididymal lesions were more frequents in medium and large breeds. Cribriform epididymal hyperplasia was observed and papillary epididymal hyperplasia for papillary epithe-lial projections with normal morphology in the lumen was proposed.

    Key-words: Dog, epididym, testicle. histopathological alterations.

    A ocorrência de alterações testiculares e epididi-márias em cães nas diferentes regiões do país, assim como a influência delas sobre a fertilidade da espécie são ainda pouco exploradas, especialmente de cães sem raça definida (SRD. Neste estudo buscou-se determinar a prevalência das alterações histopatológicas testiculares e epididimárias nos

  12. Environmental DNA (eDNA sampling improves occurrence and detection estimates of invasive burmese pythons.

    Directory of Open Access Journals (Sweden)

    Margaret E Hunter

    Full Text Available Environmental DNA (eDNA methods are used to detect DNA that is shed into the aquatic environment by cryptic or low density species. Applied in eDNA studies, occupancy models can be used to estimate occurrence and detection probabilities and thereby account for imperfect detection. However, occupancy terminology has been applied inconsistently in eDNA studies, and many have calculated occurrence probabilities while not considering the effects of imperfect detection. Low detection of invasive giant constrictors using visual surveys and traps has hampered the estimation of occupancy and detection estimates needed for population management in southern Florida, USA. Giant constrictor snakes pose a threat to native species and the ecological restoration of the Florida Everglades. To assist with detection, we developed species-specific eDNA assays using quantitative PCR (qPCR for the Burmese python (Python molurus bivittatus, Northern African python (P. sebae, boa constrictor (Boa constrictor, and the green (Eunectes murinus and yellow anaconda (E. notaeus. Burmese pythons, Northern African pythons, and boa constrictors are established and reproducing, while the green and yellow anaconda have the potential to become established. We validated the python and boa constrictor assays using laboratory trials and tested all species in 21 field locations distributed in eight southern Florida regions. Burmese python eDNA was detected in 37 of 63 field sampling events; however, the other species were not detected. Although eDNA was heterogeneously distributed in the environment, occupancy models were able to provide the first estimates of detection probabilities, which were greater than 91%. Burmese python eDNA was detected along the leading northern edge of the known population boundary. The development of informative detection tools and eDNA occupancy models can improve conservation efforts in southern Florida and support more extensive studies of invasive

  13. Environmental DNA (eDNA) sampling improves occurrence and detection estimates of invasive burmese pythons.

    Science.gov (United States)

    Hunter, Margaret E; Oyler-McCance, Sara J; Dorazio, Robert M; Fike, Jennifer A; Smith, Brian J; Hunter, Charles T; Reed, Robert N; Hart, Kristen M

    2015-01-01

    Environmental DNA (eDNA) methods are used to detect DNA that is shed into the aquatic environment by cryptic or low density species. Applied in eDNA studies, occupancy models can be used to estimate occurrence and detection probabilities and thereby account for imperfect detection. However, occupancy terminology has been applied inconsistently in eDNA studies, and many have calculated occurrence probabilities while not considering the effects of imperfect detection. Low detection of invasive giant constrictors using visual surveys and traps has hampered the estimation of occupancy and detection estimates needed for population management in southern Florida, USA. Giant constrictor snakes pose a threat to native species and the ecological restoration of the Florida Everglades. To assist with detection, we developed species-specific eDNA assays using quantitative PCR (qPCR) for the Burmese python (Python molurus bivittatus), Northern African python (P. sebae), boa constrictor (Boa constrictor), and the green (Eunectes murinus) and yellow anaconda (E. notaeus). Burmese pythons, Northern African pythons, and boa constrictors are established and reproducing, while the green and yellow anaconda have the potential to become established. We validated the python and boa constrictor assays using laboratory trials and tested all species in 21 field locations distributed in eight southern Florida regions. Burmese python eDNA was detected in 37 of 63 field sampling events; however, the other species were not detected. Although eDNA was heterogeneously distributed in the environment, occupancy models were able to provide the first estimates of detection probabilities, which were greater than 91%. Burmese python eDNA was detected along the leading northern edge of the known population boundary. The development of informative detection tools and eDNA occupancy models can improve conservation efforts in southern Florida and support more extensive studies of invasive constrictors

  14. Comparação de infiltração de água no solo mensurada em período seco e úmido, em diferentes usos da terra na bacia do arroio Boa Vista, Guamiranga, Paraná / Assessment of soil water infiltration measured during dry and wet seasons on different land uses in the Boa Vista Basin Stream, Guamiranga, Paraná, Brazil

    Directory of Open Access Journals (Sweden)

    Vademir Antoneli

    2009-08-01

    Full Text Available ResumoNeste estudo, é comparada a capacidade de infiltração de água no solo mensurada em período seco (agosto e úmido (dezembro. Os usos da terra onde foi mensurada a infiltração foram mapeados previamente (floresta com araucária, agricultura, erva-mate, reflorestamento, pastagem, capoeira e faxinal. A mensuração da infiltração foi feita através de infiltrômetro com anel duplo, sendo que, em cada uso, foram feitas oito repetições em cada período. Verificou-se que ocorreu diferença significativa na capacidade de infiltração de água no solo mensurada no período seco em comparação com o período úmido. As diferenças ocorreram tanto no volume total infiltrado, quanto na taxa de infiltração final. Dentre os usos mensurados, as áreas de pastagens apresentaram a menor capacidade de infiltração. Conclui-se que o padrão e a dinâmica do uso da terra (mosaico espacial, na bacia do arroio Boa Vista, são responsáveis por diferentes respostas na capacidade de infiltração de água. Por consequência, esperam-se também diferentes comportamentos hidro-erosivos em cada unidade de terra existente na bacia.AbstractThis article offers a comparison between the infiltration capacity of water in the soil measured during dry (August and wet (December seasons at the Boa Vista stream basin, in Guamiranga (Paraná State, South Brazil. The land uses there infiltration was measured were previously mapped and featured mixed Ombrophyla Forest, agriculture, Ilex paraguariensis plantations, reforestation, pasture, shrubs and “faxinal” (properties without fencing, whose owners share farming facilities. A double ring infiltrometer was used to measure water infiltration in the soil, with eight repetitions during each season. A significant difference was verified in the infiltration capacity when the soils measured during the dry period were compared with those measured during the wet period. Differences appeared both in the total

  15. Aflatoxicoses: prejuízos causados ao desempenho zootécnico de frangos de corte, boas práticas agrícolas e métodos biológicos de detoxificação

    Directory of Open Access Journals (Sweden)

    Ágatha Cristina de Pinho Carão

    2014-09-01

    Full Text Available As aflatoxicoses são micotoxicoses causadas por toxinas produzidas por estirpes de fungos do gênero Aspergillus. Causam prejuízos importantes à produção animal, em especial àquelas que têm nos grãos sua matéria-prima base para preparação de ração, como a avicultura de corte. Atualmente, diversas técnicas, tais como uso de substâncias químicas, métodos físicos, estratégias de colheita, armazenagem e processamento de alimentos, estão sendo estudadas para que se diminua e, se bem aplicadas, evite os efeitos deletérios causados por essas substâncias à saúde animal. O objetivo desta revisão é descrever os principais efeitos das aflatoxinas sobre o desempenho zootécnico na produção de frangos de corte, as alterações nas matérias-primas de ração e os avanços científicos em metodologias de detoxificação biológica e de boas práticas agrícolas.

  16. ATRIBUTOS E PAPÃIS DOS COMITÃS DE AUDITORIA NA IMPLEMENTAÃÃO DAS BOAS PRÃTICAS DE GOVERNANÃA CORPORATIVA EM INSTITUIÃÃES FINANCEIRAS BRASILEIRAS

    Directory of Open Access Journals (Sweden)

    Patrícia Bernardes

    2008-09-01

    Full Text Available O objetivo deste trabalho é investigar, segundo as perspectivas dos Chief Financial Officer (CFO, Relações com Investidores (RI e Auditoria Interna (AI, a importância dos comitês de auditoria na implementação das melhores práticas de Governança Corporativa (GC em instituições financeiras brasileiras com ações ou títulos negociados no mercado de capitais norte-americano. Este texto, de caráter qualitativo, se fundamentou na teoria denominada Nova Economia Institucional, e utilizou como instrumento de pesquisa entrevistas realizadas com seis dirigentes, detentores das funções acima especificadas em duas instituições financeiras brasileiras de grande porte. Os resultados apurados indicam que as instituições financeiras pesquisadas possuem comitês de auditoria consolidados, que atuam como guardiões das boas práticas de GC

  17. BOAS PRÁTICAS PARA A CONCEPÇÃO DE UMA PLATAFORMA LOGÍSTICA DE BENS NÃO PERECÍVEIS: UM CASO DE EMPREENDEDORISMO SOCIAL

    Directory of Open Access Journals (Sweden)

    Luisa Margarida Carvalho

    2011-06-01

    Full Text Available A multimensionalidade dos fenómenos da pobreza e da exclusão social obrigam ao encontro de diversos actores na procura de soluções participadas. O envolvimento de diversas organizações em parceria para a resolução de problemas e necessidades sociais pode ser encarado como uma solução inovadora que potencia práticas de empreendedorismo social. Neste âmbito a criação de um Mercado Social de bens não perecíveis na cidade Setúbal - Portugal envolvendo diversas entidades, nomeadamente Instituições Particulares de Solidariedade Social (IPSS, Câmara Municipal de Setúbal e Instituto Politécnico de Setúbal formam uma rede de cooperação cujo objectivo base se centra na resolução de problemas sociais em tempos de crise. Este estudo tem como objectivo descrever as boas práticas que suportaram a concepção da plataforma logística para o Mercado Social de bens não perecíveis, apontando caminhos e procedimentos passíveis de disseminar noutros contextos e formas de transferência de conhecimento do ensino superior para a comunidade local.

  18. 76 FR 40082 - Semiannual Regulatory Agenda

    Science.gov (United States)

    2011-07-07

    ... are: Indian python (including Burmese python), reticulated python, Northern African python, Southern African python, boa constrictor, yellow anaconda, DeSchauensee's anaconda, green anaconda, and Beni... Required: Yes. Agency Contact: Art Roybal, Senior Fish and Wildlife Biologist, Department of the Interior...

  19. Computed tomography of ball pythons (Python regius) in curled recumbency.

    Science.gov (United States)

    Hedley, Joanna; Eatwell, Kevin; Schwarz, Tobias

    2014-01-01

    Anesthesia and tube restraint methods are often required for computed tomography (CT) of snakes due to their natural tendency to curl up. However, these restraint methods may cause animal stress. The aim of this study was to determine whether the CT appearance of the lungs differs for ball pythons in a curled position vs. tube restraint. Whole body CT was performed on ten clinically healthy ball pythons, first in curled and then in straight positions restrained in a tube. Curved multiplanar reformatted (MPR) lung images from curled position scans were compared with standard MPR lung images from straight position scans. Lung attenuation and thickness were measured at three locations for each scan. Time for positioning and scanning was 12 ± 5 min shorter for curled snakes compared to tube restraint. Lung parenchyma thickness and attenuation declined from cranial to caudal on both straight and curled position images. Mean lung parenchyma thickness was greater in curled images at locations 1 (P = 0.048) and 3 (P = 0.044). Mean lung parenchyma thickness decreased between location 1 and 2 by 86-87% (straight: curled) and between location 1 and 3 by 51-50% (straight: curled). Mean lung attenuation at location 1 was significantly greater on curled position images than tube restraint images (P = 0.043). Findings indicated that CT evaluation of the lungs is feasible for ball pythons positioned in curled recumbency if curved MPR is available. However, lung parenchyma thickness and attenuation in some locations may vary from those acquired using tube restraint. © 2014 American College of Veterinary Radiology.

  20. Linfoma intravascular do pulmão: A propósito de um caso clínico com boa resposta à terapêutica

    Directory of Open Access Journals (Sweden)

    M. Felizardo

    2008-11-01

    Full Text Available Resumo: O linfoma intravascular é uma forma muito rara de linfoma não Hodgkin de células grandes B. Caracte-riza-se pela proliferação celular tumoral de linfócitos limitada aos pequenos vasos, particularmente nos capilares. Apresentamos o caso de uma doente de 54 anos, não fumadora, que foi admitida no nosso hospital para investigação de um quadro com quatro meses de evolução de febre, sudorese nocturna, emagrecimento não quantificado e dispneia progressiva. Ao exame objectivo apresentava-se febril, taquicárdica e polipneica. Analiticamente, destacava-se anemia, leucocitose e LDH elevada. Gasometria arterial -FiO2 1 l/m: PaO2-63,6 mm Hg. A telerradiografia de tórax revelava infiltado intersticial difuso. Foram excluídas todas as causas de febre de origem indeterminada. O diagnóstico foi realizado por biópsia pulmonar cirúrgica e foi prescrita terapêutica citostática combinada e rituximab com boa resposta clínica. Relatamos o caso pela dificuldade diagnóstica e pela boa resposta à terapêutica.Rev Port Pneumol 2008; XIV (6: 857-868 Abstract: Intravascular lymphoma is a very rare form of large B cell non-Hodgkin’s lymphoma, characterised by the presence of lymphoma cells in the lumina of small vessels only, particulary in the capillaries. We report a 54 year-old female non-smoker, admitted to hospital for further examination of a four month long clinical condition involving high fever, night sweats, unqualified weight loss and progressive dyspnea. Patient’s temperature was 38.5 ºC, pulse 100/min and respiratory 22 cycles/min.Patient’s haemoglobin was 9.4 g/dL, she had leukocytosis, elevated LDH and arterial blood gas analysis with moderate hypoxaemia (FiO2 1 l/m: PaO2-63.6 mm Hg. Chest X-ray revealed diffuse interstitial changes. All the possible causes of unknown origin fever were excluded.Diagnosis was made through lung biopsy and treatment

  1. "Feedback" após boas versus más tentativas melhora a aprendizagem motora em crianças Feedback after good versus poor trials enhances motor learning in children

    Directory of Open Access Journals (Sweden)

    Esmaeel Saemi

    2011-12-01

    Full Text Available O presente estudo investigou se a aprendizagem motora de crianças pode ser beneficiada pelo "feedback" (conhecimento de resultados -CR fornecido após tentativas relativamente boas de prática, ao invés de após tentativas ruins. A tarefa requeriu que os participantes arremessassem saquinhos de feijão em um alvo circular fixo, posicionado no chão, a uma distância de 3 m. Vinte e oito crianças do ensino fundamental (idade média: 10,6 anos participaram deste experimento. A fase de prática consistiu de 10 blocos de seis tentativas. Após cada bloco de tentativas, um grupo (KR "good" recebeu CR relacionado aos três arremessos mais precisos, enquanto ao outro grupo (KR "poor" foi fornecido CR relacionado aos três arremessos menos precisos. Os participantes não foram informados sobre as tentativas nas quais o "feedback" seria fornecido. Imediatamente após a fase de prática, os participantes preencheram o questionário de motivação intrínseca. Um dia após a fase de prática, foi conduzido um teste de retenção composto por 10 tentativas, sem CR. Os resultados demonstraram que a aprendizagem foi melhorada através do fornecimento de CR após as boas tentativas de prática. Ainda, os resultados do questionário revelaram que a motivação intrínseca dos aprendizes foi aumentada pelo "feedback" positivo. Os presentes achados adicionam evidências de que os efeitos motivacionais do "feedback" possuem um impacto direto sobre a aprendizagem.The present study investigated whether children would benefit from feedback (knowledge of results, KR provided after relatively good as opposed to poor trials. The task required participants to throw beanbags at a circular target that was placed on the floor at a distance of 3 m. Twenty-eight elementary school children (mean age: 10.6 years participated in this experiment. The practice phase consisted of 10 blocks of 6 trials. After each 6-trial block, one group (KR good received KR on the 3 most

  2. Panorama brasileiro do Programa de Boas Práticas de Laboratório. Impacto na redução do uso de animais | Brazilian Good Laboratory Practices Perspective. Impact on reduction in animal use

    Directory of Open Access Journals (Sweden)

    Elisa Rosa dos Santos

    2015-05-01

    Full Text Available Boas Práticas de Laboratório, sistema da qualidade que abrange o processo organizacional e as condições nas quais estudos não clínicos são realizados, visa garantir a uniformidade, consistência, confiabilidade, reprodutibilidade, qualidade e integridade dos testes. O Instituto Brasileiro de Meio Ambiente e dos Recursos Naturais Renováveis introduziu formalmente a Boas Práticas de Laboratório em 1994. Em 1995, o INMETRO iniciou o Programa BPL para reconhecimento e monitoramento baseados em procedimentos, normas, regulamentos administrativos e legais, que estabelecem orientações, políticas e diretrizes para a Coordenação Geral de Acreditação atuar, com total responsabilidade e autoridade, como Autoridade Brasileira de Monitoramento aos princípios das BPL. Estudos BPL são reconhecidos pelos países membros e não membros com adesão plena, aos atos da Organização para a Cooperação e Desenvolvimento Econômico em função do acordo de mútua aceitação de dados e promove redução do número de animais utilizados devido a não repetição dos testes e adoção de métodos alternativos validados. No Brasil, há 31 instalações BPL ativas e cinco realizam testes toxicológicos in vivo. A Resolução Normativa no 17/2014 do Conselho Nacional de Controle da Experimentação Animal estabelece que os testes utilizando animais que tenham métodos alternativos validados reconhecidos pelo Conselho sejam substituídos em até cinco anos, sendo essencial a ampliação da base laboratorial BPL. ---------------------------------------------------------------------------------------- Good Laboratory Practice (GLP, a quality system covering the organizational process and the conditions under which non-clinical studies are conducted, aims to ensure uniformity, consistency, reliability, reproducibility, quality, and integrity of the safety tests. The Brazilian Institute of Environment and Renewable Natural Resources formally introduced GLP

  3. Conversações sobre a "boa morte": o debate bioético acerca da eutanásia Conversations on the "good death": the bioethical debate on euthanasia

    Directory of Open Access Journals (Sweden)

    Rodrigo Siqueira-Batista

    2005-02-01

    Full Text Available A despeito das grandes discussões hodiernas sobre a eutanásia, permanecem ainda muitos pontos em aberto, aparentemente insolúveis, aguardando que um melhor tratamento conceitual seja desenvolvido. Neste âmbito podem ser incluídos os "preconceitos e fundamentalismos" em relação ao tema — a eutanásia ainda é vista como tabu em boa parte da sociedade, especificamente no caso do Brasil —, as imprecisões semânticas do vocábulo e as acérrimas tensões argumentativas em torno do tema — levando-se em consideração os princípios da sacralidade da vida, da qualidade de vida e da autonomia e o argumento da assim chamada "ladeira escorregadia" ou slippery slope. Compor o horizonte de indagação acerca da eutanásia, partindo dos antecedentes históricos em direção a um melhor equacionamento do problema — e delimitação de perspectivas vindouras necessárias à sua melhor compreensão — é, pois, o objetivo do presente ensaio.Despite extensive current debate on euthanasia, many open and apparently unsolvable issues persist, awaiting a better conceptual treatment. The area includes "prejudices and fundamentalisms" in relation to the theme, still viewed as taboo by a major share of society, specifically in the case of Brazil, while semantic imprecision in the term and argumentative tensions surround the issue, focusing on the principles of sacredness of life, quality of life, and autonomy and the so-called "slippery slope" argument. The purpose of the current essay is thus to serve as a sphere of inquiry concerning euthanasia, moving from historical antecedents towards a better solution to the problem and the demarcation of necessary future perspectives for enhanced understanding of the issue.

  4. Perfil socioeconômico e profissional de manipuladores de alimentos e o impacto positivo de um curso de capacitação em Boas Práticas de Fabricação

    Directory of Open Access Journals (Sweden)

    Gabriela Gianini Guilherme Devides

    2014-06-01

    Full Text Available Doenças transmitidas por alimentos constituem um problema de saúde pública em nível mundial e estão frequentemente associadas a falhas na manipulação dos alimentos. Conhecer o perfil socioeconômico e profissional, bem como o nível de conhecimento dos manipuladores de alimentos, é requisito essencial para o planejamento de políticas públicas e programas de capacitação visando a segurança e qualidade dos alimentos. Este trabalho teve por objetivo avaliar o perfil socioeconômico e profissional de manipuladores de alimentos, e o impacto de um curso de capacitação em Boas Práticas de Fabricação (BPF realizado na cidade de Araraquara-SP, Brasil. Um total de 192 manipuladores respondeu a dois questionários: o primeiro, para avaliar o nível de conhecimento dos manipuladores sobre BPF antes (avaliação diagnóstica e depois (avaliação final de participar do curso; o segundo, para realizar um levantamento do perfil socioeconômico e profissional dos manipuladores. Os resultados mostraram que o curso de capacitação repercutiu de forma positiva no nível de conhecimento dos manipuladores, sendo que todos os temas sobre BPF avaliados apresentaram um percentual de respostas corretas significativamente maior na avaliação final em relação à avaliação diagnóstica. Isso indica a necessidade de aperfeiçoamento constante, para garantir a qualificação profissional dos manipuladores e, consequentemente, a qualidade dos alimentos e a segurança alimentar dos consumidores.

  5. IMPACTO DA IMPLANTAÇÃO DE BOAS PRÁTICAS DE HIGIENE NA ORDENHA SOBRE A QUALIDADE MICROBIOLÓGICA E FÍSICO-QUÍMICA DO LEITE CRU REFRIGERADO

    Directory of Open Access Journals (Sweden)

    Vanerli Beloti

    2012-12-01

    Full Text Available A Instrução Normativa nº 62 trouxe novos parâmetros a serem seguidos pelos produtores, dando continuidade à melhoria da qualidade do leite em andamento desde a Instrução Normativa nº 51. O objetivo do presente trabalho foi avaliar o impacto das práticas na qualidade do leite em 49 propriedades da região de Ivaiporã/PR, através de palestra e treinamentos coletivos. Foi observada redução de 88,05% na Contagem Bacteriana Total (CBT em 28 (57,15% propriedades. Dessas propriedades, 23 (47,93% apresentaram CBT inferior ao máximo de 750.000 UFC/mL exigido pela legislação vigente na época de análise, com média de 166.826,1 UFC/mL. No quesito Contagem de Células Somáticas (CCS, 83,57% do total de propriedades passaram a produzir leite de acordo com o padrão estipulado para este quesito na ocasião de análise. Não foi observada variação significativa dos constituintes físico-químicos do leite após a implantação das boas práticas. A implantação das práticas propostas foram suficientes para a produção de leite de acordo com o padrão estabelecido pela legislação.

  6. Spiders and Boas and Rats, Oh My!

    Science.gov (United States)

    Hodges, Jody L.

    1991-01-01

    Described is a science curriculum enrichment program where sixth grade students present programs to other students on the topics of pets and exotic animals. The use of live animals in the presentations is emphasized. (KR)

  7. BoA The Best is Coming

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    成功进军美国歌坛,迈向全新阶段的BoA,化身为双面歌姬,发行了专辑《BEST&USA》将“日文精选辑”与“美国出道专辑”2张作品结合为9年来,从韩国到日本再到美国,BoA的成长令人无法忽视。

  8. BoA Venus is Back

    Institute of Scientific and Technical Information of China (English)

    田梦园

    2010-01-01

    暌违韩国歌坛五年.BoA终于带着自己的六辑回到韩国的歌谣舞台。经历了日本.美国歌坛的洗礼,BoA以更加成熟,更具实力的形象回到自己的主场.让我们一起迎接Venus的回归。

  9. BoA ONLY ONE ONLY DREAM

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>说到韩流先驱者,一定不能不提到BoA,她就像一颗恒星,在夜空中持续发光发热,不仅能让人时时刻刻都看到自己,也为后辈们照出了一条光明的道路。如今的她,已经不能仅仅被称作偶像,她已经是个能够给我们带来洗涤灵魂的音乐的专业歌者。BoA成功艺人13岁,对于很多人来说只是青春的开始,心智刚开始发育,是接受新鲜事物最快的年纪,也是最可爱的年纪。而这个年纪的BoA已经踏上了舞台,成为了一名歌手。小小年纪就作为SOLO歌手出道,是一件十分需要勇气的事情,而公司的力捧也

  10. AVALIAÇÃO DAS BOAS PRÁTICAS EM UNIDADE DE ALIMENTAÇÃO E NUTRIÇÃO NO MUNICÍPIO DE CONTAGEM-MG

    Directory of Open Access Journals (Sweden)

    Jackline Freitas Brilhante de SÃO JOSÉ

    2011-08-01

    Full Text Available As unidades de alimentação e nutrição são responsáveis pelo fornecimento de refeições balanceadas e dentro de condições higiênico-sanitárias satisfatórias. Com este estudo, objetivou-se avaliar as condições físicas e higiênico-sanitárias em uma unidade de alimentação e nutrição institucional quanto ao atendimento a regulamentos federais sobre boas práticas. Foi realizado estudo transversal em uma Unidade de Alimentação e Nutrição institucional que distribuía 320 refeições por dia. Para avaliação utilizou-se a lista de verifi cação proposta no Anexo II da Resolução RDC 275/2002. O controle de temperatura das preparações e dos equipamentos foi realizado utilizando planilha de controle da própria unidade. A avaliação por blocos evidenciou que o maior percentual de adequação foi verifi cado no bloco manipuladores e o maior percentual de inadequação, no bloco documentação. Quanto à avaliação das preparações, as quentes apresentaram melhor adequa- ção no que se refere a temperaturas analisadas, destacando o resultado obtido para o arroz e o feijão, que atingiram 100% de adequação. Temperaturas inferiores a 60ºC foram identifi cadas para guarnição, prato principal e opção. Para as preparações frias, especifi camente saladas, foram detectadas inadequações, considerando o valor inferior a 10ºC como temperatura aceitável. Entre os equipamentos quentes de distribuição, o balcão foi o que apresentou maior percentual de adequação no turno do almoço e jantar (100%. Assim, a UAN obteve 75% de adequação, considerando o total de itens aplicáveis, e, por meio do critério empregado, fi cou classifi cada no Grupo 2. A correção das inadequações é necessária para garantir a segurança na produção de refei- ções oferecidas pela unidade.

  11. AVALIAÇÃO DAS CONDIÇÕES DE HIGIENE E DA ADEQUAÇÃO ÀS BOAS PRÁTICAS EM UNIDADES DE ALIMENTAÇÃO E NUTRIÇÃO NO MUNICÍPIO DE PORTO ALEGRE – RS

    Directory of Open Access Journals (Sweden)

    Jozi Fagundes de MELLO

    2013-04-01

    Full Text Available As unidades de alimentação e nutrição (UANs vêm aumentando sua atuação no mercado de refei- ções coletivas e são classificadas como o terceiro maior local de ocorrência de doenças transmitidas por alimentos no Brasil. O fator primordial para diminuir a ocorrência destas doenças é o uso contínuo das boas práticas, que são procedimentos que contribuem para a produção de um alimento seguro e de qualidade. Neste estudo foi avaliada a adequa- ção de sete UANs, de grande porte, às boas práticas e verifi cada a higiene de superfícies. A avaliação da adequação às boas práticas ocorreu por meio da aplicação da lista de verificação com base na Portaria 78/09-RS. A avaliação da higiene das superfícies, por meio da técnica de Trifosfato de Adenosina bioluminescência, apontou que 13 entre as 39 superfícies analisadas foram classificadas como insatisfatórias. Todas as UANs apresentaram menos de 50% de conformidade frente à lista de verificação. Destacam-se os itens Higienização, Preparação do alimento, Armazenagem e transporte do alimento preparado, como os itens com maiores percentuais de não-conformidades. Os itens Abastecimento de água e Controle de pragas foram 100% conformes em todas as UANs. Os resultados demonstram que é imprescindível que estas UANs revejam os procedimentos de higiene e executem de forma efetiva as boas prá- ticas nas rotinas de produção e distribuição de alimentos.

  12. PROPOSTA DE UM MANUAL DE BOAS PRÁTICAS DE LABORATÓRIO PARA INDÚSTRIAS DE LATICÍNIOS DE PEQUENO E MÉDIO PORTE, BASEADO NA REPRESENTAÇÃO SOCIAL DOS UTILIZADORES

    Directory of Open Access Journals (Sweden)

    Josete Amadeu Almeida

    2012-06-01

    Full Text Available A qualidade de produtos alimentícios é considerada como um indicador das condições de produção e uma questão de saúde pública. A definição de que o alimento seja seguro e inócuo para o consumo depende de resultados analíticos confiáveis os quais possibilitam monitorar e orientar os processos produtivos. Assim, é fundamental que as metodologias de análise e a sua realização, estejam em conformidade com normas e parâmetros validados. As Boas Práticas de Laboratório (BPL são definidas como um sistema da qualidade aplicado a laboratórios com o objetivo de promover a qualidade e a validação dos resultados laboratoriais. Os órgãos fiscalizadores exigem a implementação das BPL nos laboratórios das indústrias de laticínios. Os objetivos desta pesquisa foram avaliar as dificuldades das empresas na compreensão, elaboração e implantação do manual de BPL por meio da metodologia de pesquisa qualitativa do discurso do sujeito coletivo e desenvolver diretrizes para a elaboração de manual de BPL para indústrias de laticínios de pequeno e médio porte. Foram realizadas entrevistas com funcionários de laboratórios de três laticínios da região de Leopoldina-MG e a análise do discurso do sujeito coletivo (DSC dessas entrevistas. Assim, detectou-se uma grande dificuldade por parte dos colaboradores das empresas no entendimento, elaboração e implantação do manual de BPL o que indicou a necessidade de elaboração de diretrizes para orientar a elaboração do Manual de BPL. Para elaboração dessas diretrizes foi realizado um levantamento na literatura disponível, pesquisa nas regulamentações e contato com instituições e empresas no período de fevereiro a dezembro de 2010. O Manual constitui-se da descrição pormenorizada dos itens: conduta pessoal; controle da qualidade laboratorial, aferição e calibração de instrumentos; padronização, identificação e armazenagem adequada de reagentes; coleta de

  13. BOAS与ASTRAL评分预测急性缺血性脑卒中患者3月不良预后的价值%BOAS vs ASTRAL Score in Predicting the 3-month Unfavorable Outcome of Acute Ischemic Stroke

    Institute of Scientific and Technical Information of China (English)

    龙胤希

    2015-01-01

    Objective To study the clinical values of the Bologna Outcome Algorithm for Stroke (BOAS) and the Acute Stroke Registry and Analysis of Lausanne (ASTRAL)Score in evaluating 3-month unfavorable outcome after Acute Ischemic Stroke (AIS). Methods The clinical data and of 305 consecutive patients with AIS admit ed from January 2013 to April 2014 were col ected in this research. Al patients were evaluated according to BOAS Score and ASTRAL Score criteria. Areas under the curve were calculated to quantify the prognostic value and compared with the values between BOAS and ASTRAL Score in predicting. Unfavorable outcome was assessed as a modified Rankin Scale score >2 at 3 months. Calibration was assessed by comparing predicted and observed probability of unfavorable outcome using Pearson correlation coef icient.Results Al patients appeared functional disability (modified Rankin score> 2) or the death of a poor prognosis 115 cases (37.7%) within 3 months.The AUC of BOAS and ASTRAL Score for 3 months were 0.859( =0.000,95%CI:0.804-0.914)and 0.812( =0.000,95%CI:0.750~0.875)respectively.Conclusion BOAS and ASTRAL score assessment of acute ischemic stroke patients with poor prognosis three months have bet er predictive value, is conducive to clinical decision making.%目的比较博洛尼亚卒中结局算法(BOAS)与洛桑卒中评分(ASTRAL)评估急性缺血性脑卒中(AIS)患者3个月不良预后的预测价值。方法收集2013年1月~2014年4月我院305例急性缺血性脑卒中患者的临床资料,比较BOAS与ASTRAL评分预测缺血性脑卒中的3个月的不良预后,并绘制受试工作者特征曲线下面积(AUC),以卒中后3个月的死亡率或功能残障(改良Rankin评分>2分为不良预后),应用Pearson相关分析评估实际与预期结局事件的关联程度。结果全组患者3个月出现功能残障(改良Rankin评分>2)或死亡的不良预后有115例(37.7%);BOAS和ASTRAL评分预测3个

  14. Is the Karyotype of Neotropical Boid Snakes Really Conserved? Cytotaxonomy, Chromosomal Rearrangements and Karyotype Organization in the Boidae Family.

    Directory of Open Access Journals (Sweden)

    Patrik F Viana

    Full Text Available Boids are primitive snakes from a basal lineage that is widely distributed in Neotropical region. Many of these species are both morphologically and biogeographically divergent, and the relationship among some species remains uncertain even with evolutionary and phylogenetic studies being proposed for the group. For a better understanding of the evolutionary relationship between these snakes, we cytogenetically analysed 7 species and 3 subspecies of Neotropical snakes from the Boidae family using different chromosomal markers. The karyotypes of Boa constrictor occidentalis, Corallus hortulanus, Eunectes notaeus, Epicrates cenchria and Epicrates assisi are presented here for the first time with the redescriptions of the karyotypes of Boa constrictor constrictor, B. c. amarali, Eunectes murinus and Epicrates crassus. The three subspecies of Boa, two species of Eunectes and three species of Epicrates exhibit 2n = 36 chromosomes. In contrast, C. hortulanus presented a totally different karyotype composition for the Boidae family, showing 2n = 40 chromosomes with a greater number of macrochromosomes. Furthermore, chromosomal mapping of telomeric sequences revealed the presence of interstitial telomeric sites (ITSs on many chromosomes in addition to the terminal markings on all chromosomes of all taxa analysed, with the exception of E. notaeus. Thus, we demonstrate that the karyotypes of these snakes are not as highly conserved as previously thought. Moreover, we provide an overview of the current cytotaxonomy of the group.

  15. Instrumento de avaliação das Boas Práticas em Unidades de Alimentação e Nutrição Escolar: da concepção à validação Instrument for assessment of best practices in school food and nutrition units: from design to validation

    Directory of Open Access Journals (Sweden)

    Sueli Maria da Silva

    2013-04-01

    Full Text Available O objetivo deste artigo é elaborar e validar instrumento de avaliação das Boas Práticas para Unidades de Alimentação e Nutrição Escolares. Estudo desenvolvido na cidade de Santos, realizado em dois momentos: 1 Elaboração da Lista de Verificação das Boas Práticas na Alimentação Escolar (Lista de Verificação BPAE e; 2 Validação da Lista de Verificação BPAE com aplicação desta e de outras duas listas de referência em 76 escolas municipais. A sensibilidade e a especificidade foram estimadas por meio da Curva ROC - Receiver Operating Characteristics e a lista de verificação foi avaliada de acordo com a escala de Likert. Os blocos temáticos receberam pesos para o cálculo do percentual de adequação. Após aplicação das listas nas escolas foi observado valor de área sob a curva de 0,79 em relação à lista SS-196 e 0,85 para a Portaria 542/2006, indicando boa capacidade da Lista de Verificação BPAE em identificar inadequações. Esta lista recebeu avaliação positiva dos nutricionistas da alimentação escolar revelando que a mesma auxiliará na tomada de decisões para o controle de qualidade. A Lista de Verificação de BPAE elaborada e validada pode se constituir em importante instrumento para o controle de qualidade da alimentação escolar.The scope of this study was to elaborate and validate an assessment tool for Best Practices in School Food and Nutrition Units. For this purpose a survey was conducted in the city of Santos (São Paulo - Brazil, in two stages: 1 Preparation of a Checklist for Best Practices in School Food and Nutrition Units (BPAE checklist. 2 Validation of the BPAE checklist. This checklist was applied in 76 public schools along with two other reference checklists. Sensitivity and specificity were estimated using the Receiver Operating Characteristics (ROC Curve and the checklist was evaluated by application of the Likert scale. The thematic groups received weights to calculate the percentage

  16. Aplicação do sistema de gestão da qualidade BPF (boas práticas de fabricação na indústria de produtos farmacêuticos veterinários The usage of the GMP (good manufacturing practices quality management system for veterinary pharmaceutical industries

    Directory of Open Access Journals (Sweden)

    Felipe Araújo Calarge

    2007-01-01

    Full Text Available A necessidade de desenvolvimento de métodos de controle e gestão da qualidade tem se colocado como um fator de melhoria da competitividade e permanência das empresas em seus setores de atuação. No entanto, em alguns segmentos industriais, o controle e a gestão da qualidade se dão considerando também exigências de atendimento a normas e legislações governamentais, como é o caso do segmento de empresas fabricantes de produtos veterinários no Brasil. Este artigo descreve os principais aspectos e resultados de uma pesquisa tipo survey realizada com o objetivo de analisar se as empresas fabricantes de produtos veterinários estão se estruturando para aplicarem as boas práticas de fabricação, como um sistema de controle e gestão da qualidade. Por meio da condução de um levantamento bibliográfico, foram descritos aspectos relativos ao contexto de competitividade do agronegócio e do mercado de produtos veterinários, bem como dos principais tópicos relativos às bases normativas com ênfase nas boas práticas de fabricação. A execução da pesquisa se deu por meio da condução de uma survey em empresas do segmento farmacêutico veterinário, buscando-se caracterizar o método de pesquisa adotado, bem como relatos e dados obtidos. O trabalho conclui que as empresas fabricantes de produtos veterinários estão implantando as Boas Práticas de Fabricação, e demonstra, entre outros aspectos, que isto está motivado por uma gestão eficaz de seus recursos produtivos ao invés de um mero atendimento da legislação governamental.The need to develop quality control and management methods has been faced as an improvement factor for the competitiveness and permanence of companies in their sectors. Nonetheless, in some industrial segments, this situation of quality control and management also occurs considering the demands for complying with governmental standards and legislations, such as the segment of industries manufacturing

  17. A EDUCAÇÃO PARA À SUSTENTABILIDADE: um olhar para o avanço econômico proporcionado por uma Mineradora no município de São João da Boa Vista/SP

    Directory of Open Access Journals (Sweden)

    Romilson Cesar Lima

    2015-07-01

    Full Text Available A educação é considerada uma importante fonte de transformação do ser social. Provocações e novos desafios surgem a cada dia em busca de analisarmos se estamos atuando ou não de forma moral e ética. A sustentabilidade e o consumismo são características bem opostas, de um lado empresas que primam pelo progresso, oferecem vagas de empregos e beneficiam seres humanos com suas atividades, do outro, uma nova educação, dotada de preocupações com a preservação ambiental. Considerado um dos assuntos mais comentados na atualidade, a educação para sustentabilidade está intrinsecamente ligada à solidariedade, respeito e afetividade e precisa estar conectada a três pilares: prosperidade econômica, respeito ao meio ambiente e proteção social. Para isto, é necessário que as pessoas substituam o pensamento capitalista consumista, mantendo a sustentabilidade. Esta pesquisa teve o objetivo de identificar acontecimentos atuais provocados por uma mineradora no município de São João da Boa Vista e o quanto a conscientização pela Educação para a Sustentabilidade pode proporcionar para a localidade e humanidade. Investigouse a Lei Orgânica e Legislação Municipal a fim de evitarem a ação da mineradora e manter, sem maiores danos, o turismo local e regional.   Education is considered an important source of transformation of social being. Provocations and new challenges arise every day in order to analyzy whether or not we are acting with morals and ethics. Sustainability and consumerism are quite opposite characteristics on the one hand companies that strive for progress, offer job openings a new education, endowed with concerns over environmental preservation. Considered as one of the most discussed subjects currently, education for sustainability is intrinsically linked to solidarity, respect and affection and has to be connected to three pillars: economic prosperity, environmental respect and social protection. To achieve this

  18. Avaliação dos óleos e gorduras de fritura de estabelecimentos comerciais da cidade de Campinas/ SP. As boas práticas de fritura estão sendo atendidas?
    Evaluation of frying fats and oils from commercial establishments of the city of Campinas/SP.

    Directory of Open Access Journals (Sweden)

    C. C. OSAWA

    2010-09-01

    Full Text Available

    A fritura é um método rápido de cocção, em que há transferência de calor do óleo de fritura para o alimento, propiciando características sensoriais únicas de aroma, textura e sabor. Por ser um método bastante conveniente, é amplamente empregado em serviços de alimentação. No entanto, a qualidade dos alimentos fritos depende principalmente do tipo e da qualidade do óleo usado na fritura. Devido à ação da água presente nos alimentos à elevada temperatura de fritura (em torno de 180ºC e ao oxigênio do ar, ocorre uma série de reações químicas, gerando compostos de degradação que nem sempre são benéfi cos à saúde. Por conta disso, o descarte do óleo de fritura deve ser monitorado, através de métodos físico-químicos, tais como ácidos graxos livres e compostos polares. Atualmente, não há legislação no Brasil para avaliar os óleos descartados. Há apenas recomendações de boas práticas de fritura. Este trabalho objetivou, portanto, avaliar o processo de fritura de 13 estabelecimentos comerciais de Campinas/SP, analisar os óleos descartados e recomendar medidas corretivas. Os resultados deste estudo comprovaram que, embora os estabelecimentos careçam de informações sobre o processo de fritura, os óleos e gorduras descartados, em geral, não apresentaram condições abusivas de uso e poderiam ser utilizados por mais tempo. Embora nada se possa afi rmar sobre a qualidade sensorial dos alimentos fritos e aceitação dos consumidores, é de extrema importância o atendimento às boas práticas de frituras por parte dos produtores de alimentos fritos.

  19. Vibrios among patients of good socioeconomic conditions during the cholera epidemic in Recife, Brazil Vibriões coléricos e não coléricos entre pacientes de boas condições sódo-econômicas durante a epidemia de coléra no Recife, Brasil

    Directory of Open Access Journals (Sweden)

    Vera Magalhães

    1993-08-01

    Full Text Available Between March and July, 1992, we screened for Vibrio all fecal samples submitted for bacteriologic diagnosis at a private clinical laboratory in Recife. Of 1435 cultures examined only 1 (0.07% was positive for V.cholerae 01, biovar Eltor, serovar Inaba, but 17 (1.2% yielded non-cholera Vibrio (V.cholerae non-01; V.fluvialis; V.furnissii, V.parahaemolyticus and Vibrio spp. Thus, V.cholerae 01, differently of other enteropathogenic vibrios, spared individuals of good socioeconomic conditions even during the cholera epidemic, which made hundreds of victims in the neighboring slums.Entre março e julho de 1992, pesquisou-se Vibrio em todos os espécimes fecais enviados para diagnóstico bacteriológico a um laboratório clínico privado do Recife. De 1435 culturas examinadas apenas 1 (0.07% foi positiva para V.cholerae 01, biovar Eltor, sorovar Inaba, porém 17 (1,2% forneceram outras espécies de Vibrio (V.cholerae nao-01; V.fluvialis; V.furnissii; V.parahaemolyticus e Vibrio spp. Portanto, V.cholerae 01, diferentemente de outros vibriões entero patogênicos, poupou indivíduos de boas condições sócio-econômicas, mesmo durante uma epidemia de cólera que atingiu centenas de pessoas nas favelas vizinhas.

  20. Bullying: o principal vilão da boa convivência: (In Formando uma equipe para o êxito! = Acoso Entre Escolares: él principal villano de la buena convivencia: ¡(In Formando un equipo para el éxito!

    Directory of Open Access Journals (Sweden)

    Timm, Jordana Wruck

    2011-01-01

    Full Text Available O bullying é todo tipo de agressão: física, verbal, emocional ou virtual. É um fenômeno antigo, mas cada vez adquire maiores dimensões e as consequências afetam as vidas das pessoas envolvidas e também suas aprendizagens. O objetivo do artigo é entender como se produz o processo de intimidação e como este afeta a convivência humana, bem como, apresentar as consequências deste “vilão” para a educação e a importância de (in formar uma equipe em busca de soluções que possam impedir ou reduzir as agressões entre pares. A metodologia inicial ocorreu pela divulgação da mídia, onde se pode perceber que havia um fenômeno crescente nas escolas, então se decidiu buscar na realidade, a qual constatou o fenômeno. Com isto, deram inicio as buscas na bibliografia e realizou-se um levantamento de dados, com o intuito de verificar o entendimento dos envolvidos sobre o assunto. Com as informações obtidas concluiuse que este é um trabalho árduo e impossível de realizar só, ou seja, para obter-se boa convivência entre todos e, consequentemente, êxito no logro das aprendizagens, se requer a participação da tríade que intervêm no processo educativo: escola, família e estudante

  1. Clio pyramidata Linnaeus, 1767 forma convexa (Boas, 1886) (Mollusca, Pteropoda)

    NARCIS (Netherlands)

    Spoel, van der S.

    1973-01-01

    The pelagic fauna of the Red Sea shows special variation induced by its isolated character (Van der Spoel, 1971). Clio pyramidata from the Red Sea is usually incorrectly referred to as the tropical forma lanceolata (Lesueur, 1813) or the typical forma pyramidata Linnaeus, 1767. Some large samples

  2. BoA 全盛时代

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    在准备这次专辑封面拍摄的期间,不仅你自己非常努力,你的工作团队部似乎非常团结呢!BoA:不是我刻意去创造这样的氛围(笑),不迟到,努力工作,一直一起协力到最后,工作人员失误也会减少,似乎能配合得很好。

  3. Avian Mobbing of the Puerto Rican Boa (Epicrates inornatus)

    Science.gov (United States)

    JAVIER E. MERCADO; ESTEBAN TERRANOVA; JR. WUNDERLE

    2002-01-01

    Mobbing, defined as an intense collective behavior in which birds of one or more species scold or even physically attack a predator, is known from a variety of bird species (Campbell and Lack, 1985; Gill, 1995). Targets commonly include hawks, owls, and snakes. In the West Indies, observations have documented avian mobbing towards various hawk species (e.g., Jeffrey-...

  4. Gestão da segurança e saúde no trabalho em empresas produtoras de baterias automotivas: um estudo para identificar boas práticas Management of occupational health and safety in automotive battery companies: a study to identify best practices

    Directory of Open Access Journals (Sweden)

    Otávio José de Oliveira

    2010-09-01

    Full Text Available A gestão da Segurança e Saúde no Trabalho (SST reduz riscos de acidentes, promove a saúde e a satisfação dos trabalhadores, melhora os resultados operacionais e a imagem das organizações, sobretudo daquelas do setor industrial. Este artigo tem como principal objetivo identificar, a partir do método de estudo de caso duplo, boas práticas e principais dificuldades relacionadas à gestão da SST em empresas fabricantes de baterias automotivas da região centro-oeste do Estado de São Paulo. A coleta de dados se deu por meio de observação in loco, análise de documentos e entrevistas semiestruturadas com gestores e colaboradores. O trabalho revelou que o apoio da alta direção e da área de Recursos Humanos e a participação ativa dos colaboradores são determinantes para o sucesso deste sistema e que as principais dificuldades na sua gestão advêm de falhas na comunicação, inexistência de indicadores de SST e ausência de visão estratégica para segurança.Occupational Health and Safety management (OSH reduces the risk of accidents, promotes worker health and satisfaction and improves operational results and the image of organizations, especially those in the industrial sector. The main objective of this paper is to identify best practices and the main difficulties related to OSH management at automobile battery manufacturers in the midwest of the State of São Paulo, using the double case study method. Data was collected using on-site observation, document analysis and semi-structured interviews with managers and collaborators. The study revealed that support by top management, Human Resources and the active participation of collaborators are determining factors for the system's success and that the main difficulties in its management are failures in communication, nonexistence of OSH indicators and the lack of a strategic vision for safety.

  5. Condições higiênicas e boas práticas de manipulação em serviços de alimentação da cidade de Itaqui-RS | Hygienic conditions and good manipulation practices of food services in Itaqui city, RS

    Directory of Open Access Journals (Sweden)

    Joice Trindade Silveira

    2015-05-01

    Full Text Available O objetivo deste trabalho foi avaliar as condições higiênicas de diferentes tipos de serviços de alimentação. Foi aplicada uma lista de verificação de boas práticas em 24 estabelecimentos da cidade de Itaqui-RS, sendo dez restaurantes comerciais, sete lanchonetes, cinco padarias e dois hotéis. A média geral de conformidades verificada nos estabelecimentos pesquisados foi de 38,23%. Quando avaliados por tipo de estabelecimento, os percentuais de adequação foram: 46,06% em restaurantes comerciais, 38,95% em lanchonetes, 35,35% em padarias e 32,56% em hotéis. Quando avaliados por categorias, as maiores não conformidades foram observadas nos itens relacionados à documentação e ao registro (7,73% e a responsabilidades (1,66%. Em contrapartida, a categoria com maior percentual foi controle integrado de pragas e vetores (63,23%. Sugere-se que haja maior controle na produção de alimentos, com atividades de educação e supervisão, para que os consumidores sejam expostos a menores riscos de contaminação. -------------------------------------------------------------------------------------------- The aim of this study was evaluate hygienic conditions of different food services. It was applied a good practice checklist at 24 places from Itaqui-RS: ten restaurants, seven snack bars, five bakeries and two hotels. The average of conformities was 38.23%. When they were analyzed by type of food service, the values adequacy were 46.06% at commercial restaurants, 38.95% at snack bars, 35.35% at bakeries and 32.56% at hotels. By categories, the major nonconformities were observed in items related to documentation and record (7.73% and responsibilities (1.66%. The category with the highest percentage was integrated control of pests and vectors (63.23%. It was suggested more control in food production, with education and supervision activities, to expose consumers to lower risks of contamination.

  6. Antioxidant capacity of meagre (Argyrossomus regius fed different lipid content and source, with and without selenium

    Directory of Open Access Journals (Sweden)

    Sthelio Braga Fonseca

    2014-06-01

    Meagre (600 animals were kept in 24 tanks (80 L with constant renovation and aeration and maintained at 20.7 ± 0.7ºC and oxygen 8.8 ± 1.7 mg L-1. Fish were fed twice per day, six days per week, with eight different experimental diets for 60 days. Diets were formulated to have two different oil sources (fish or vegetable blend oils with 45% of linseed, 35% of rapeseed and 20% of soybean oil, two lipid levels (12 and 17% and two selenium supplementation (0 and 1 mg/kg diet. Lipid peroxidation (LPO, glutathione reductase (GR, glutathione peroxidase (GPx, total glutathione (TG and catalase (CAT were analyzed in liver of fish. CAT, GPx and GR activities were not significantly altered in fish fed with diets with different oil sources. However, TG in fish fed with fish oil diet was higher than the levels observed in fish fed with vegetable blend oil. Furthermore, fish fed with fish oil diet showed lower lipid peroxidation when compared with fish fed vegetable blend oil diet (Table 1. Concerning the oil level in diet, it was observed that fish fed with a diet of 17% lipids had a higher level of total glutathione when compared to fish fed with a diet of 12% lipids. On the other hand, the fish fed with a diet with 12% lipids showed lower levels of lipid peroxidation when compared to fish fed with a diet of 17% lipids. Fish fed with diets supplemented with selenium showed a significantly increased activity of GPx when compared with fish fed without selenium. Three-way ANOVA analysis showed that dietary lipid level and the presence of selenium have a significant interaction on the activities of CAT and GR, as well as, levels of TG and LPO. A significant interaction between the source of oil and the presence of selenium on GR activities was observed. Interaction on source and level was observed to CAT. In conclusion, the antioxidant capacity of meagre is influenced by the source of oil, the level of lipids and the presence of selenium in their diet.

  7. Humoral regulation of heart rate during digestion in pythons (Python molurus and Python regius).

    Science.gov (United States)

    Enok, Sanne; Simonsen, Lasse Stærdal; Pedersen, Signe Vesterskov; Wang, Tobias; Skovgaard, Nini

    2012-05-15

    Pythons exhibit a doubling of heart rate when metabolism increases several times during digestion. Pythons, therefore, represent a promising model organism to study autonomic cardiovascular regulation during the postprandial state, and previous studies show that the postprandial tachycardia is governed by a release of vagal tone as well as a pronounced stimulation from nonadrenergic, noncholinergic (NANC) factors. Here we show that infusion of plasma from digesting donor pythons elicit a marked tachycardia in fasting snakes, demonstrating that the NANC factor resides in the blood. Injections of the gastrin and cholecystokinin receptor antagonist proglumide had no effect on double-blocked heart rate or blood pressure. Histamine has been recognized as a NANC factor in the early postprandial period in pythons, but the mechanism of its release has not been identified. Mast cells represent the largest repository of histamine in vertebrates, and it has been speculated that mast cells release histamine during digestion. Treatment with the mast cell stabilizer cromolyn significantly reduced postprandial heart rate in pythons compared with an untreated group but did not affect double-blocked heart rate. While this study indicates that histamine induces postprandial tachycardia in pythons, its release during digestion is not stimulated by gastrin or cholecystokinin nor is its release from mast cells a stimulant of postprandial tachycardia.

  8. Tongue worm (Pentastomida) infection in ball pythons (Python regius) – a case report

    Science.gov (United States)

    Gałęcki, Remigiusz; Sokół, Rajmund; Dudek, Agnieszka

    Tongue worms (Pentastomida) are endoparasites causing pentastomiasis, an invasive disease representing a threat to exotic animals and humans. Animals acquire infection via the alimentary tract. In reptiles, the parasite is present in the lungs, resulting in symptoms from the respiratory system. Pentastomiasis may be asymptomatic, but nonspecific symptoms may occur at high parasite concentrations. Due to the harmful effects of many antiparasitic substances, tongue worm invasion in reptiles remains not fully treatable. Although pentasomiasis is rarely diagnosed in Poland, pentastomids were diagnosed in two ball pythons, who were patients of the “Poliklinika Weterynaryjna” veterinary clinic. They demonstrated problems with the respiratory system and a significant deterioration of health. Fenbendazole at a dose of 100 mg/kg b.w., repeated after 7 days was shown to be effective.

  9. Good practices in milking to reduce microbiological contamination of milk in agreste of Pernambuco / Boas práticas de ordenha para redução da contaminação microbiológica do leite no agreste Pernambucano

    Directory of Open Access Journals (Sweden)

    Maria Beatriz Tassinari Ortolani

    ógica, o que compromete a composição do produto, reduz sua vida de prateleira e pode constituir risco à saúde pública. A qualidade e a segurança dos alimentos estão associadas às boas práticas de produção (BPP. A implantação das BPP resulta na redução do número de microrganismos do leite levando a uma melhor qualidade microbiológica e maior vida de prateleira do produto final. O objetivo deste trabalho foi avaliar o impacto da implantação de boas práticas de ordenha na melhoria da qualidade microbiológica do leite, visando atingir os padrões estabelecidos pela Instrução Normativa 51. Foram aplicadas diferentes práticas de ordenha nos principais pontos de contaminação, identificados previamente, em quatro propriedades do Agreste Pernambucano. As práticas foram avaliadas através da enumeração de microrganismos indicadores aeróbios mesófilos, psicrotróficos, estafilococos coagulase positivos, coliformes totais e Escherichia coli antes e após aplicação das práticas. As práticas adotadas foram: desprezo dos três primeiros jatos de leite, imersão dos tetos em solução clorada, higienização vigorosa e posterior inversão dos latões e baldes para eliminação da água residual. Os resultados demonstram com aplicação das práticas redução média de 99,9% de microrganismos aeróbios mesófilos no leite. As práticas indicadas são simples, eficientes, de fácil incorporação na rotina da ordenha em qualquer situação de tecnificação das propriedades e não requerem gastos com instalações.

  10. Cuidados Centrados na Família: impacto da formação e de um manual de boas práticas em pediatria Cuidados Centrados en la Familia: impacto de la formación y de un manual de buenas prácticas en pediatria Family-centered care: impact of training and a best practice guide in pediatrics

    Directory of Open Access Journals (Sweden)

    Marta Isabel Correia Gaio Apolinário

    2012-07-01

    Full Text Available Os Cuidados Centrados na Família (CCF constituem uma nova conceção do cuidar pediátrico em que as necessidades das Famílias e Crianças são centrais nesse processo. No entanto, na prática, a sua aplicação nas unidades hospitalares é ainda deficiente, sendo emergente o empenho para que esta filosofia de cuidados se efetive na prática diária dos Enfermeiros. Realizou-se um estudo quase experimental tipo pré teste, pós teste sem grupo de controlo, baseado numa metodologia quantitativa, cujos objetivos foram avaliar o impacto da formação e de um manual de boas práticas nos conhecimentos dos Enfermeiros e na sua perceção quanto à aplicação dos CCF em Pediatria. Da amostra fizeram parte 24 Enfermeiros de um serviço de pediatria a quem foram aplicados três questionários. Confirmou-se que existe diferença positiva nos conhecimentos dos Enfermeiros sobre os CCF e na sua perceção quanto à aplicação desta filosofia na prática diária antes e depois da formação e da implementação do manual de boas práticas, o que demonstra o impacto e eficácia da intervenção desenvolvida na efetivação desta filosofia nas unidades pediátricas.Los cuidados centrados en la familia (CCF constituyen una nueva concepción del cuidar pediátrico en que las necesidades de las familias y de los niños son centrales en dicho proceso. Sin embargo, en realidad, su aplicación en las unidades hospitalarias sigue siendo insuficiente, a pesar de que haya surgido un esfuerzo para que esta filosofía de atención forme parte efectiva de la práctica diaria de los enfermeros. Se realizó un estudio casi experimental, de tipo pre-test y con un post-test sin grupo de control, basado en una metodología cuantitativa, cuyos objetivos fueron evaluar el impacto de la formación y de un manual de buenas prácticas en los conocimientos de los enfermeros y en su percepción con respecto a la aplicación de los CCF en pediatría. La muestra consistió en 24

  11. Dietas enterais não industrializadas: análise microbiológica e verificação de boas práticas de preparação Non industrialized enteral diets: microbiological analysis and verification of good preparation practices

    Directory of Open Access Journals (Sweden)

    Angélica Aparecida Maurício

    2008-02-01

    Full Text Available OBJETIVO: Verificar a adequação das áreas de produção e o nível de contaminação microbiana de dietas enterais utilizadas em três hospitais privados da Região Noroeste do Paraná. MÉTODOS: A análise das Boas Práticas de Preparação da Nutrição Enteral seguiu a Resolução da Diretoria Colegiada nº 63/2000, da Agência Nacional de Vigilância Sanitária, e as análises microbiológicas das 15 amostras de dietas enterais seguiram as recomendações da Resolução da Diretoria Colegiada nº 12/2001, da Agência Nacional de Vigilância Sanitária, nas quais foram pesquisados bolores e leveduras, bactérias mesófilas, coliformes a 35 e 45ºC, Estafilococos coagulase positiva, Salmonella sp. e Bacillus cereus. RESULTADOS: A maior porcentagem para as Não Conformidades foi do hospital HS (61% e a menor do hospital HT (43,5%. Foi observada, em 100% das amostras dos hospitais HP e HT, contaminação por coliformes a 45ºC acima do padrão de referência da Resolução da Diretoria Colegiada nº 12/2001 e 60% das amostras do hospital HS apresentaram contaminação por coliformes a 35ºC acima do limite aceitável. As amostras encontravam-se dentro dos padrões para Estafilococos coagulase positiva, Salmonella sp., Bacillus cereus e bactérias mesófilas. Nos hospitais HT e HP a contaminação por bolores e leveduras estava acima do padrão permitido pela legislação. Os resultados das análises mostraram que a contaminação das dietas está relacionada ao tipo de ingrediente utilizado e ao excesso de manipulação. CONCLUSÃO: Conclui-se que as boas práticas de preparação da nutrição enteral não estavam de acordo com a Resolução da Diretoria Colegiada nº 63/2000 e que os hospitais estavam inadequados para preparar esse tipo de alimento.OBJECTIVE: To verify the degree of suitability of production areas and the level of microbial contamination in enteral diets used in three private hospitals in the Northwest region of Paran

  12. Reduced foraging in the presence of predator cues by the Black Spiny-tailed Iguana, Ctenosaura similis (Sauria: Iguanidae

    Directory of Open Access Journals (Sweden)

    Vincent R. Farallo

    2010-12-01

    Full Text Available The presence of a predator may have direct and indirect effects on the behavior of the prey. Although altered behavior may help prey avoid predators, it also can have a potential impact on critical activities such as foraging. Predator-prey interactions are routinely studied in laboratory-based experiments owing to theperceived difficulties of conducting such experiments in natural settings. We conducted an experimental study under field conditions in Palo Verde National Park in northwestern Costa Rica to assess behavioral responses of Black Spiny-tailed Iguanas (Ctenosaurasimilis to the presence of predators and predator cues. Free-roaming iguanas were offered mango in designated areas in the presence of a predator (Boa constrictor, a predator cue (B. constrictor feces, and a control (no predator or predator cue. Results indicate that iguanas reduced their foraging efforts in the presence of both a predator and its cue.

  13. Prevalence and molecular identification of Cryptosporidium isolates from pet lizards and snakes in Italy

    Directory of Open Access Journals (Sweden)

    Rinaldi L.

    2012-11-01

    Full Text Available In order to acquire prevalence and genetic data on Cryptosporidium infections in captive lizards and snakes kept as pets, a survey was conducted on 150 individual reptiles from southern Italy. Fecal samples were preserved in 5% formalin and analyzed using a commercial immunofluorescence assay (IFA for the detection of Cryptosporidium oocysts and Giardia cysts. IFA revealed the presence of Cryptosporidium oocysts in nine of the 150 samples examined (6.0%, precisely in 6/125 snakes (4.8% and in 3/25 lizards (12.0%; all fecal samples tested negative for the presence of Giardia cysts. Molecular characterization based on nested PCR amplification and sequencing of the SSU-rRNA gene, revealed the presence of Cryptosporidium serpentis in three samples from snakes (Boa constrictor constrictor, Elapheguttata guttata guttata and Python molurus.

  14. Changes in pharyngeal constrictor volumes during head and neck radiation therapy: Implications for dose delivery

    Directory of Open Access Journals (Sweden)

    Akila Kumarasiri

    2017-01-01

    Conclusion: The patients underwent considerable anatomical changes to PCM during H and N RT. However, the resultant increase in dose to PCM was minor to moderate. PCM thickness measured at C3 level is a good predictor for the mean dose increase to PCM.

  15. FOOD SAFETY OF MINAS TRADITIONAL CHEESE OF SERRO, MINAS GERAIS STATE, BRAZIL, AS A RESULT OF GOOD MANUFACTURING PRACTICES SEGURANÇA ALIMENTAR DO QUEIJO MINAS ARTESANAL DO SERRO, MINAS GERAIS, EM FUNÇÃO DA ADOÇÃO DE BOAS PRÁTICAS DE FABRICAÇÃO

    Directory of Open Access Journals (Sweden)

    Lívia Beatriz Almeida Fontes

    2009-10-01

    ência das Boas Práticas, no processamento do Queijo Minas Artesanal do Serro, expõe o mesmo a muitas fontes de contaminação e compromete sua qualidade, podendo afetar a saúde do consumidor. Buscando identificar os principais pontos de contaminação do processo de obtenção do leite, fabricação do queijo e suas correlações com a contaminação microbiológica, foi aplicado um questionário estruturado e coletadas amostras de queijos, para pesquisa de coliformes 30ºC, Escherichia coli, Staphylococcus aureus e mesófilos aeróbios. Os pontos identificados, que apresentaram relação com as análises microbiológicas dos queijos, foram: insalubridade das queijarias, presença de animais domésticos e higiene dos manipuladores. É fundamental o treinamento dos produtores, para a adoção das medidas corretivas e preventivas, com o objetivo de minimizar ou evitar a contaminação do Queijo Minas Artesanal.

    PALAVRAS-CHAVE: Queijo Minas Artesanal; Staphylococcus aureus; Escherichia coli.

  16. Elaboração de roteiro para inspeção das boas práticas de manipulação e comercialização de alimentos no setor informal | Preparation of a roadmap for inspection of good practices in food handling and marketing in the informal sector

    Directory of Open Access Journals (Sweden)

    Angélica Cotta Lobo Leite Carneiro

    2017-02-01

    Full Text Available O comércio informal de alimentos desempenha um grande papel socioeconômico, cultural e nutricional na vida dos consumidores. Entretanto, considera-se que os alimentos comercializados informalmente podem constituir um risco à saúde da população, pois podem ser facilmente contaminados devido às condições inadequadas do local de preparo, uma vez que tal comércio ocorre muitas vezes na rua e há falta de conhecimento de técnicas de manipulação higienicossanitária por parte dos comerciantes. Assim, o presente estudo teve por objetivo elaborar um roteiro de inspeção das boas práticas de manipulação e comercialização informal de alimentos. O roteiro estruturado foi fundamentado em legislações vigentes e na literatura científica da área. Foi elaborado, avaliado em campo e ajustado, com pós-avaliação por equipe composta por um fiscal da vigilância sanitária e os pesquisadores. O roteiro contou com 26 questões que versam sobre aspectos ambientais e estruturais do comércio, manipuladores de alimentos e qualidade e condições de exposição e de armazenamento dos alimentos prontos para consumo e das matérias-primas para seu preparo, assim como dos alimentos in natura. Este instrumento mostrou-se de fácil aplicação e adequado para avaliar a manipulação e comercialização de alimentos no setor informal, além disso, tem potencial para colaborar com o trabalho de agentes sanitários uma vez que possibilita o registro das principais irregularidades observadas nesse segmento, além de contribuir para uma uniformidade na inspeção. ============================================================== The informal food trade plays a large social, economic, nutritional and cultural role in the lives of consumers. However, informally marketed food may be considered a health risk to the population because it can be easily contaminated due to inadequate conditions at the place of preparation, since they often occur on the street, and

  17. Implantación de guías de buenas prácticas en España. Programa de centros comprometidos con la excelencia en cuidados / Best Practice Guidelines Implementation in Spain. Best Practice Spotlight Organizations / Implementação de manuais sobre boas práticas na Espanha. Programa dos Centros comprometidos com a excelência no atendimento

    Directory of Open Access Journals (Sweden)

    Laura Albornos-Muñoz, BS.

    2015-03-01

    centros comprometidos con la excelencia en cuidados. MedUNAB 2015; 17 (3: xx-xx]. Introduction: The Best Practice Guidelines Implementation Programme, called in Spain “Centros Comprometidos con la Excelencia en Cuidados®”, started in 2010 thanks to the collaboration between the Nursing and Healthcare Research Unit (Investén-isciii, in Spain, the Spanish Collaborating Centre of the Joanna Briggs Institute for evidence based healthcare, and the Registered Nurses’ Association of Ontario (RNAO, Canada. It is based on the same fundaments of Best Practice Spotlight Organizations (BPSO® Program, initiated by RNAO, in 1999, in Canada. Objective: To describe the implementation of Best Practice Guidelines developed by RNAO in the context of Centros Comprometidos con la Excelencia en Cuidados® Program. The program aims to promote, facilitate and support the implementation, evaluation and sustainability of nursing best practices, for the period 2012-2014. Methodology and Results: Eight healthcare institutions and one university were selected to implement RNAO Best Practice Guidelines aligned with their needs. Twenty-four months into the implementation Programme healthcare professionals have been trained, work teams have been established, nursing care protocols and records have been developed or updated, and process and patient results have been systematically evaluated. Also, all main achievements of the Programme have been actively disseminated. Conclusions: Candidates centers committed to excellence in cuidados® are working hard and the results are starting to show positive, with a growing culture of evidence-based care, and the promotion of research and the start of work collaborative networking. [Albornos-Muñoz L, González-María E, Moreno-Casbas T. Best Practice Guidelines Implementation in Spain. Best Practice Spotlight Organizations. MedUNAB 2015; 17 (3: xx-xx]. Introdução: O programa para implementar Manuais de Boas Práticas, chamados na Espanha de Centros

  18. Novel Hepatozoon in vertebrates from the southern United States.

    Science.gov (United States)

    Allen, Kelly E; Yabsley, Michael J; Johnson, Eileen M; Reichard, Mason V; Panciera, Roger J; Ewing, Sidney A; Little, Susan E

    2011-08-01

    Novel Hepatozoon spp. sequences collected from previously unrecognized vertebrate hosts in North America were compared with documented Hepatozoon 18S rRNA sequences in an effort to examine phylogenetic relationships between the different Hepatozoon organisms found cycling in nature. An approximately 500-base pair fragment of 18S rDNA common to Hepatozoon spp. and some other apicomplexans was amplified and sequenced from the tissues or blood of 16 vertebrate host species from the southern United States, including 1 opossum (Didelphis virginiana), 2 bobcats (Lynx rufus), 1 domestic cat (Felis catus), 3 coyotes (Canis latrans), 1 gray fox (Urocyon cinereoargenteus), 4 raccoons (Procyon lotor), 1 pet boa constrictor (Boa constrictor imperator), 1 swamp rabbit (Sylvilagus aquaticus), 1 cottontail rabbit (Sylvilagus floridanus), 4 woodrats (Neotoma fuscipes and Neotoma micropus), 3 white-footed mice (Peromyscus leucopus), 8 cotton rats (Sigmodon hispidus), 1 cotton mouse (Peromyscus gossypinus), 1 eastern grey squirrel (Sciurus carolinensis), and 1 woodchuck (Marmota monax). Phylogenetic analyses and comparison with sequences in the existing database revealed distinct groups of Hepatozoon spp., with clusters formed by sequences obtained from scavengers and carnivores (opossum, raccoons, canids, and felids) and those obtained from rodents. Surprisingly, Hepatozoon spp. sequences from wild rabbits were most closely related to sequences obtained from carnivores (97.2% identical), and the sequence from the boa constrictor was most closely related to the rodent cluster (97.4% identical). These data are consistent with recent work identifying prey-predator transmission cycles in Hepatozoon spp. and suggest this pattern may be more common than previously recognized.

  19. Prevalence of Hepatozoon spp. (Apicomplexa, Hepatozoidae among recently captured Brazilian snakes Prevalência de Hepatozoon spp. (Apicomplexa, Hepatozoidae em serpentes recém-capturadas no Brasil

    Directory of Open Access Journals (Sweden)

    L.H. O'Dwyer

    2003-06-01

    Full Text Available The goal of this study was to determine the prevalence of Hepatozoon spp. infection in recently captured snakes from Botucatu, São Paulo State, Brazil. Blood was collected from all snakes by ventral tail venipuncture. Blood smears were air dried, fixed with methanol, and stained with 10% Giemsa solution. The slides were microscopically examined for detection of hemoparasites by light microscopy at 250x magnification. A total of 238 snakes from 23 species were examined, of which 135 (56.7% were venomous and 103 (43.3% non-venomous snakes. The more numerous venomous species sampled were Crotalus durissus terrificus (n=108 and Bothrops jararaca (n=17 and non-venomous snakes were Oxyrhopus guibei (n=35, Boa constrictor amarali (n=18, and Waglerophis merremi (n=13. Hepatozoon spp. infection was detected in 39 (16.4% snakes. The prevalence in venomous and non-venomous snakes was 20.0% and 11.7%, respectively. The highest prevalences observed were 38.9% for Boa constrictor amarali, 35.3% for Bothrops jararaca, and 19.4% for Crotalus durissus terrificus.O presente estudo teve como objetivo determinar a prevalência da infecção por Hepatozoon spp. em serpentes recém-capturadas da região de Botucatu, São Paulo. O sangue foi coletado de todas as serpentes por punção da veia caudal. Os esfregaços foram secos ao ar, fixados com metanol e corados com solução de Giemsa a 10%. Examinaram-se 238 serpentes pertencentes a 23 espécies, das quais 135 (56,7% eram venenosas e 103 (43,3% não venenosas. As espécies venenosas mais representativas foram Crotalus durissus terrificus (n=108 e Bothrops jararaca (n=17 e as não venenosas foram Oxyrhopus guibei (n=35, Boa constrictor amarali (n=18 e Waglerophis merremi (n=13. A infecção por Hepatozoon spp. foi detectada em 39 (16,4% serpentes. As prevalências em serpentes venenosas e não venenosas foram 20,0% e 11,7%, respectivamente. As maiores prevalências foram 38,9% para Boa constrictor amarali, 35

  20. Ticks infesting amphibians and reptiles in Pernambuco, Northeastern Brazil.

    Science.gov (United States)

    Dantas-Torres, Filipe; Oliveira-Filho, Edmilson F; Soares, Fábio Angelo M; Souza, Bruno O F; Valença, Raul Baltazar P; Sá, Fabrício B

    2008-01-01

    Ticks infesting amphibians and reptiles in the State of Pernambuco are reviewed, based on the current literature and new collections recently carried out by the authors. To date, three tick species have been found on amphibians and reptiles in Pernambuco. Amblyomma fuscum appears to be exclusively associated with Boa constrictor, its type host. Amblyomma rotundatum has a relatively low host-specificity, being found on toads, snakes, and iguana. Amblyomma dissimile has been found on a lizard and also small mammals (i.e., rodents and marsupials). New tick-host associations and locality records are given.

  1. Liderando mejoras de calidad mediante el desarrollo, implementación, y medición de las guías de buenas prácticas de Enfermería / Leading Quality Improvement through Best Practice Guideline Development, Implementation, and Measurement Science / Liderando com melhor qualidade por meio da elaboração, implementação e avaliação de guias de boas práticas na enfermagem

    Directory of Open Access Journals (Sweden)

    Irmajean Bajnok, RN., MScN., PhD.

    2015-03-01

    UNAB 2015; 17 (3: xx-xx] Introdução: O movimento de práticas baseadas na evidência, associado à enfermagem, tem estimulado ações em nível mundial para desenvolver ferramentas de conhecimento. Contudo, assimilar o conhecimento e implementar as diretrizes na prática clínica em qualquer ambiente clínico requer mais do que conscientização e distribuição de guias de orientação desenvolvidas com rigor. Objetivo: O objetivo deste artigo é partilhar a implementação de estratégias bem-sucedidas desenvolvidas pelo Programa de Guias para a Boa Prática na Enfermagem, da Associação de Enfermeiras de Ontário, (Canadá (RNAO, segundo sua sigla em Inglês, que assegura aos praticantes maior consciência sobre os melhores conhecimentos disponíveis fazendo-os realidade em sua prática cotidiana, já que as guias ou manuais de boas práticas baseadas em evidências constituem uma abordagem que possibilita melhorias da qualidade da assistência à saúde. Tópicos: Os detalhes do processo das sete etapas do desenvolvimento RNAO de Orientação e Diretrizes do Programa de Melhores Práticas RNAO são oferecidas e destacadas como estratégias de implementação que permitem às organizações associadas com RNAO implementar diversas guias ou manuais de boas práticas através de um planejamento sistemático e da participação ativa, com ênfase na avaliação e melhoria da qualidade e da assistência à saúde permanentemente. O Programa das Diretrizes de Melhores Práticas é informado pela ciência da implementação e está ganhando rápido reconhecimento internacional pela sua eficiência na criação de alto nível nos cuidados da enfermagem e da qualidade nos cuidados que as instituições de saúde oferecem, igualmente pela sua melhoria contínua e aprimoramento dos resultados das práticas baseadas em evidências. Conclusões: através do seu protagonismo e liderança no desenvolvimento, implementação e avaliação rigorosa das guias, o RNAO est

  2. Bioenergetic components of reproductive effort in viviparous snakes: costs of vitellogenesis exceed costs of pregnancy.

    Science.gov (United States)

    Van Dyke, James U; Beaupre, Steven J

    2011-12-01

    Reproductive effort has been defined as the proportion of an organism's energy budget that is allocated to reproduction over a biologically meaningful time period. Historically, studies of reproductive bioenergetics considered energy content of gametes, but not costs of gamete production. Although metabolic costs of vitellogenesis (MCV) fundamentally reflect the primary bioenergetic cost of reproductive allocation in female reptiles, the few investigations that have considered costs of reproductive allocation have focused on metabolic costs of pregnancy (MCP) in viviparous species. We define MCP as energetic costs incurred by pregnant females, including all costs of maintaining gestation conditions necessary for embryogenesis. MCP by our definition do not include fetal costs of embryogenesis. We measured metabolic rates in five species of viviparous snakes (Agkistrodon contortrix, Boa constrictor, Eryx colubrinus, Nerodia sipedon, and Thamnophis sirtalis) during vitellogenesis and pregnancy in order to estimate MCV and MCP. Across all species, MCV were responsible for 30% increases in maternal metabolism. Phylogenetically-independent contrasts showed that MCV were significantly greater in B. constrictor than in other species, likely because B. constrictor yolk energy content was greater than that of other species. Estimates of MCP were not significantly different from zero in any species. In viviparous snakes, MCV appear to represent significant bioenergetic expenditures, while MCP do not. We suggest that MCV, together with yolk energy content, represent the most significant component of reptilian reproductive effort, and therefore deserve greater attention than MCP in studies of reptilian reproductive bioenergetics. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. Anatomía visceral de Feylinia grandisquamis (Squamata: Scincidae. Comparaciones con otros escamados de patrón corporal semejante

    Directory of Open Access Journals (Sweden)

    Díaz Gómez, Juan Manuel

    2003-07-01

    Full Text Available Feylinia grandisquamis es un síncido africano caracterizado por contar con el cuerpo alargado y las extremidades ausentes. En el presente trabajo se describe en detalle la anatomía de las vísceras de Feylinia grandisquamis, y algunos aspectos de su variación intraespecífica. Los resultados se comparan con otro género de Scincidae (Anomalopus y representantes de grandes grupos de escamados que exhiben patrones corporales semejantes (Lialis burtonis, Amphisbaena darwinii, Boa constrictor, Ophiodes striatus, Anguis fragilis. Los objetivos de este trabajo fueron: a determinar la morfología de las vísceras de Feylinia; b los aspectos de su variación intraespecífica; c discutir convergencias y paralelismos con Saurios, Anfisbénidos y Ofidios. Feylinia grandisquamis is an African Scincid characterized for a snakeshaped body and total absence of limbs. In this work the visceral anatomy of Feylinia grandisquamis is described, as well as aspects of its intraspecific variation. The results are compared with another scincid (Anomalopus and representatives of other Squamate groups with similar body plans (Lialis burtonis, Amphisbaena darwinii, Boa constrictor, Ophiodes striatus, Anguis fragilis. The objectives were: a To determine the visceral anatomy of Feylinia; b The aspects of its intraespecific variation; and c Discuss convergences and parallelisms with possible occurrence in Lizards, Amphisbaenids and Ophidia.

  4. Invasive reptiles and amphibians: global perspectives and local solutions

    Science.gov (United States)

    Reed, R.N.; Kraus, F.

    2010-01-01

    In the annals of invasive species biology, higher taxa such asmammals, plants and insects have received the lion’s shareof research attention, largely because many of these invadershave demonstrated a remarkable ability to degrade ecosys-tems and cause economic harm. Interest in invasive reptilesand amphibians (collectively ‘herpetofauna’, colloquially‘herps’) has historically lagged but is now garnering in-creased scrutiny as a result of their escalating pace ofinvasion. A few herpetofaunal invaders have received con-siderable attention in scientific and popular accounts, in-cluding the brown treesnakeBoiga irregularison Guam,Burmese pythonPython molurusin Florida, Coqu´ıEleutherodactylus coquiin Hawaii and cane toadBufomarinusin Australia. However, relatively few are aware ofmany emerging and potentially injurious herpetofaunalinvaders, such as Nile monitorsVaranus niloticusin Flor-ida, common kingsnakesLampropeltis getulain the CanaryIslands, boa constrictorsBoa constrictoron Aruba andCozumel, or a variety of giant constrictor snakes in PuertoRico. For the vast majority of the most commonlyintroduced species, real or potential impacts to nativeecosystems or human economic interests are poorly under-stood and incompletely explored; major pathways of intro-duction have only recently been elucidated, and effectivemanagement interventions have been limited (Kraus, 2009).

  5. Ticks infesting amphibians and reptiles in Pernambuco, Northeastern Brazil Carrapatos infestando anfíbios e répteis em Pernambuco, Nordeste do Brasil

    Directory of Open Access Journals (Sweden)

    Filipe Dantas-Torres

    2008-12-01

    Full Text Available Ticks infesting amphibians and reptiles in the State of Pernambuco are reviewed, based on the current literature and new collections recently carried out by the authors. To date, three tick species have been found on amphibians and reptiles in Pernambuco. Amblyomma fuscum appears to be exclusively associated with Boa constrictor, its type host. Amblyomma rotundatum has a relatively low host-specificity, being found on toads, snakes, and iguana. Amblyomma dissimile has been found on a lizard and also small mammals (i.e., rodents and marsupials. New tick-host associations and locality records are given.Os carrapatos encontrados infestando anfíbios e répteis no Estado de Pernambuco são revisados com base na literatura atual e em novas coletas realizadas recentemente pelos autores. Até o momento, três espécies de carrapatos foram encontradas sobre anfíbios e répteis em Pernambuco. Amblyomma fuscum parece estar exclusivamente associado à Boa constrictor, seu hospedeiro-tipo. Amblyomma rotundatum tem uma especificidade parasitária relativamente baixa, sendo encontrado em sapos, serpentes e iguana. Amblyomma dissimile já foi encontrado sobre um lagarto e também sobre pequenos mamíferos (isto é, roedores e marsupiais. Novas associações carrapato-hospedeiro e novos registros de localidades são apresentados.

  6. Avaliação das Boas Práticas através de check-list aplicado em restaurantes self-service da região central de Maringá, Estado do Paraná - DOI: 10.4025/actascihealthsci.v27i2.1415 Good practices evaluation through check-list applied in self-service restaurants to the downtown population of Maringá, Paraná State - DOI: 10.4025/actascihealthsci.v27i2.1415

    Directory of Open Access Journals (Sweden)

    Graciette Matioli

    2005-03-01

    Full Text Available O número de pessoas que se alimenta fora de suas residências é cada vez maior, devido a vários fatores como crescimento das cidades, inserção da mulher no mercado de trabalho e tempo indisponível para o preparo das refeições. Para garantir a segurança dos alimentos oferecidos, é necessária a implantação das Boas Práticas, procedimentos padronizados que devem ser adotados com o objetivo de evitar as Doenças Transmitidas por Alimentos. O objetivo da presente pesquisa foi avaliar as condições de higiene no preparo de alimentos em restaurantes do tipo self-service da região central do município de Maringá. Foi aplicado um check-list (guia de verificação baseado na legislação vigente no país, de forma a verificar o nível de Não-conformidades apresentadas pelos estabelecimentos. Os resultados mostraram uma variação de 10,8 a 60,9% de Não-conformidade. Conclui-se que a maioria dos restaurantes pesquisados possui condições de higiene insatisfatórias e não atendem a legislação vigente no país no que diz respeito às Boas Práticas para a produção de alimentos segurosThe number of people who eat out of their residences is becoming bigger, due to several factors: the growth of the cities, the woman's insert in the job market and the unavailable time for meals preparation. To guarantee the safety of the supplied foods, it is necessary to adopt the Good Practices, that are, standardized procedures followed with the objective of avoiding the Diseases Transmitted by Foods. This work aimed to evaluate the hygienic-sanitary conditions in the foods preparation provided by restaurants of the type self-service to the downtown population of Maringá. A check-list was applied (verification guide based on the current legislation in the country, in order to verify the Non-Conformities level presented by the establishments. The results showed a variation from 10.8 to 60.9% of Non-Conformities and that most of the researched

  7. A new species of Hepatozoon (Apicomplexa: Adeleorina) from Python regius (Serpentes: Pythonidae) and its experimental transmission by a mosquito vector

    Czech Academy of Sciences Publication Activity Database

    Sloboda, M.; Kamler, M.; Bulantová, J.; Votýpka, Jan; Modrý, David

    2007-01-01

    Roč. 93, č. 5 (2007), s. 1189-1198 ISSN 0022-3395 R&D Projects: GA MŠk(CZ) LC06009; GA ČR GD524/03/H133 Grant - others:GA ČR(CZ) GP524/03/D104 Institutional research plan: CEZ:AV0Z60220518 Keywords : Hepatozoon * Python * Culex * transmission * SSU Subject RIV: EG - Zoology Impact factor: 1.129, year: 2007

  8. Macronutrient and fatty acid profiles of meagre (Argyrosomus regius fillets as influenced by harvesting time and boiling

    Directory of Open Access Journals (Sweden)

    Roberta Martelli

    2013-12-01

    Full Text Available The effect of harvesting time and cooking on water, protein, lipid, ash and fatty acid content of farmed meagre was assessed. Significant differences in nutrient content of raw fillets were detected in relation to harvesting time. Cooking by boiling induced loss of some macronutrients, mainly lipids and some fatty acids. Retention of total lipids, C18:2n-6 and C18:3n-3 decreased significantly with harvesting time, while C20:5n-3 (EPA and C22:6n-3 (DHA were retained in the same quantity. DHA retention was higher than that of the other FAs considered, at all harvesting times. The changes detected did not diminish the nutritional value of the fish. Despite losses induced by cooking and the low fat content, typical of this species, 100 g of fillet ensured an intake of EPA plus DHA more than double the recommended daily intake (250 mg day–1, at all harvesting times. The ability to preserve nutrients is an essential requirement for quality maintenance and suggests the possibility of heat-processing fillets. 

  9. Rodents as intermediate hosts of Hepatozoon ayorgbor (Apicomplexa: Adeleina: Hepatozoidae) from the African ball python, Python regius?

    Czech Academy of Sciences Publication Activity Database

    Sloboda, M.; Kamler, M.; Bulantová, J.; Votýpka, Jan; Modrý, David

    2008-01-01

    Roč. 55, č. 1 (2008), s. 13-16 ISSN 0015-5683 R&D Projects: GA MŠk(CZ) LC06009; GA ČR GP524/03/D104; GA ČR GD524/03/H133 Institutional research plan: CEZ:AV0Z60220518 Keywords : haemogregarines * Adeleina * Hepatozoon * transmission * ICR mice * life cycle Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 1.307, year: 2008

  10. Innovative Methods for Estimating Densities and Detection Probabilities of Secretive Reptiles Including Invasive Constrictors and Rare Upland Snakes

    Science.gov (United States)

    2018-01-30

    home range  maintenance  or attraction to or avoidance of  landscape features, including  roads  (Morales et al. 2004, McClintock et al. 2012). For example...radiotelemetry and extensive road survey data are used to generate the first density estimates available for the species. The results show that southern...secretive snakes that combines behavioral observations of snake road crossing speed, systematic road survey data, and simulations of spatial

  11. Vascular O-GlcNAcylation augments reactivity to constrictor stimuli by prolonging phosphorylated levels of the myosin light chain

    Energy Technology Data Exchange (ETDEWEB)

    Lima, V.V. [Instituto de Ciências Biológicas e da Saúde, Universidade Federal de Mato Grosso, Barra do Garças, MT (Brazil); Lobato, N.S.; Filgueira, F.P. [Curso de Medicina, Setor de Fisiologia Humana, Universidade Federal de Goiás, Jataí, GO (Brazil); Webb, R.C. [Department of Physiology, Georgia Regents University, Augusta, GA (United States); Tostes, R.C. [Departamento de Farmacologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP (Brazil); Giachini, F.R. [Instituto de Ciências Biológicas e da Saúde, Universidade Federal de Mato Grosso, Barra do Garças, MT (Brazil)

    2014-08-15

    O-GlcNAcylation is a modification that alters the function of numerous proteins. We hypothesized that augmented O-GlcNAcylation levels enhance myosin light chain kinase (MLCK) and reduce myosin light chain phosphatase (MLCP) activity, leading to increased vascular contractile responsiveness. The vascular responses were measured by isometric force displacement. Thoracic aorta and vascular smooth muscle cells (VSMCs) from rats were incubated with vehicle or with PugNAc, which increases O-GlcNAcylation. In addition, we determined whether proteins that play an important role in the regulation of MLCK and MLCP activity are directly affected by O-GlcNAcylation. PugNAc enhanced phenylephrine (PE) responses in rat aortas (maximal effect, 14.2±2 vs 7.9±1 mN for vehicle, n=7). Treatment with an MLCP inhibitor (calyculin A) augmented vascular responses to PE (13.4±2 mN) and abolished the differences in PE-response between the groups. The effect of PugNAc was not observed when vessels were preincubated with ML-9, an MLCK inhibitor (7.3±2 vs 7.5±2 mN for vehicle, n=5). Furthermore, our data showed that differences in the PE-induced contractile response between the groups were abolished by the activator of AMP-activated protein kinase (AICAR; 6.1±2 vs 7.4±2 mN for vehicle, n=5). PugNAc increased phosphorylation of myosin phosphatase target subunit 1 (MYPT-1) and protein kinase C-potentiated inhibitor protein of 17 kDa (CPI-17), which are involved in RhoA/Rho-kinase-mediated inhibition of myosin phosphatase activity. PugNAc incubation produced a time-dependent increase in vascular phosphorylation of myosin light chain and decreased phosphorylation levels of AMP-activated protein kinase, which decreased the affinity of MLCK for Ca{sup 2+}/calmodulin. Our data suggest that proteins that play an important role in the regulation of MLCK and MLCP activity are directly affected by O-GlcNAcylation, favoring vascular contraction.

  12. Concentração de elementos traços em serpentes do litoral e da região serrana do Espírito Santo

    Directory of Open Access Journals (Sweden)

    Alexandra Frossard

    Full Text Available RESUMO: Os elementos químicos, em sua maioria, encontram-se em ciclos bioquímicos e geoquímicos fechados e em concentrações que não causam efeitos nocivos aos organismos. Contudo, ações antrópicas aceleradas promovem alterações ambientais, como o aumento no aporte de contaminantes. Com essas informações, o presente trabalho buscou caracterizar a presença aos elementos traços em duas espécies de serpentes comuns na região sudeste, Boa constrictor e Bothrops jararaca. Os exemplares de B. constrictor (n=18 foram provenientes de atropelamentos ocorridos no trecho da Rodovia ES-060 do Km 0 ao Km 67,5. Os exemplares de B. jararaca (n=18 foram capturados por fazendeiros na zona rural da região serrana do Espírito Santo. Foram analisados 1 grama de fragmento de rim, de espécimes necropsiados. Os rins coletados foram digeridos com mistura ácida (HNO3;HCl; 1:1 a 300oC, 40min e a quantificação de microelementos (Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb e Zn foi realizada por espectrometria de emissão óptica com plasma indutivamente acoplado (ICP OES. Não foram observadas diferenças significativas entre machos e fêmeas, exceto para Cromo nas B. constrictor (p=0,03, com média de 1,6595 nas concentrações de Cr nas fêmeas e 0,2896 em machos. Contudo, quando foram comparadas as diferentes espécies de serpentes, diferentes concentrações foram encontradas, para todos os elementos determinados, com destaque para o Ferro com uma concentração de 106,2mg/g em B. constrictor e 120,3mg/g em B. jararaca, provavelmente por esses animais virem de áreas próximas à portos de minério de ferro. A concentração de Zinco em B. constrictor foi de 1261,8mg/g e em B. jararaca foi de 28,4mg/g. O presente estudo indica que as serpentes analisadas, que habitam as regiões da Grande Vitória e serrana do Espírito Santo apresentam elevadas concentrações dos microelementos Zn e Fe.

  13. Cardiovascular risk in men aged over 40 in Boa Vista, Brazil

    Directory of Open Access Journals (Sweden)

    Mário Maciel de Lima

    2016-01-01

    Conclusions: Our study highlights a worrying trend in increasing obesity and hypertension, most likely associated with increasingly poor diet and reduced participation in exercises. As the Brazilian population ages, this will drive increasing rates of cardiovascular mortality unless these trends are reversed. This study suggests that such campaigns should focus on men over the age of 40, who are married or divorced and of lower income.

  14. O QUE É UMA BOA REVISÃO DE ARTIGO EM ADMINISTRAÇÃO?

    OpenAIRE

    Ferreira, Manuel Portugal; Pinto, Cláudia Frias; Belfort, Ana Cláudia

    2016-01-01

    La revisión por revisores pares, de artículos sometidos a revistas científicas es uno de los pilares fundacionales de la publicación científica y garantiza la calidad y certifica el conocimiento. Qué es una buena revisión es una pregunta que ha sido poco debatida, a pesar del alto grado de rechazo de artículos por las revistas científicas. En este artículo conceptual proponemos un abordaje constructivoenrevisiones de artículos, basado en una perspectiva de desarrollo para mejorar los artículo...

  15. Approche socio-culturelle de l'epilepsie en Cote d'Ivoire | Boa Yapo ...

    African Journals Online (AJOL)

    Contexte En Afrique, l'épileptique est encore trop souvent stigmatisé, du fait de la méconnaissance de la maladie et des croyances surnaturelles ou mystiques. Objectif Analyser la connaissance et la perception de l'épilepsie par l'entourage proche des personnes épileptiques suivies en milieu hospitalier neurologique, afin ...

  16. BOA valence bonding with f-character in highly coordinated actinides

    International Nuclear Information System (INIS)

    Carter, F.L.

    1979-01-01

    The addition of f character to bidirectional orbitals enhances their flexibility significantly. The resultant Cf and Gf orbitals are applied to some common high coordinations of the actinides. The valence bond approach implies d and f orbital radial splitting into bonding hybrids and either contracted localized or extended supra-valent d and f orbitals

  17. Cane toads a threat to West Indian wildlife: mortality of Jamaican boas attributable to toad ingestion

    Science.gov (United States)

    Byron S. Wilson; Susan E. Koenig; Rick van Veen; Erika Miersma; D. Craig. Rudolph

    2011-01-01

    The notorious ‘‘cane toad’’ (Bufo marinus) is considered to be one of the 100 worst invasive species in the world. A native of South and Central America, Mexico, and the Rio Grande Valley of the United States, this large toad was intentionally introduced to islands in the Caribbean, and subsequently throughout the southern Pacific, as a biological control agent to...

  18. Wie se grond koop Boas (Rut 4:9)?/Whose land did Boaz buy (Ruth ...

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 25, No 2 (2005) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  19. AS CRIANÇAS PEQUENAS SOB UMA BOA GUARDA. SMALL CHILDREN IN SAFE CUSTODY

    Directory of Open Access Journals (Sweden)

    Eric Plaisance

    2012-11-01

    Full Text Available As limitações profissionais e de tempo dos pais, as possibilidades institucionais e sociais na guarda e no cuidado das crianças pequenas levaram os sociólogos a redefinir as “idades” da pequena infância: 0-2 anos, a creche; 2-3 anos, o “jardin d’éveil”3; a partir dos três anos, a escola maternal, à qual devemos acrescentar a guarda em casa e, para as classes mais ricas, a empregada doméstica. A partir deentrevistas com pais, E. Plaisance mostra que os interessados ressaltam a liberdade de escolha (mesmo quando as ofertas são raras e reforçam o tom da evidência de que a solução tomada era a melhor para eles e para a criança. Mas as respostas mostram também que eles buscam se informar, segundo meios que favorecem o “boca a boca” e que dão lugar aos fenômenos do rumor. De fato, a “escolha” dos atores é determinada, mas como para se tranquilizar e assumir suaresponsabilidade, eles a descrevem voluntariamente como “livre”.Due to the constraints of parental work schedules, the institutional and social opportunities in minding and caring for young children have grown. This has led sociologists to redefine the 'ages' of early childhood. These are: 0-2, the crèche, 2-3, the kindergarten and from three years old on, play school. To this must be added home care with a child-minder for wealthier classes. Based on interviewswith parents, É. Plaisance shows that those involved put freedom of choice first (even when the choices are rare and the weight of evidence underlines that the solution arrived at was the best for them and their child. But the responses also show that they try to inform themselves by ways that favor word of mouth and giveroom for rumor and hearsay. The 'choice' of those involved is constrained, but as if to reassure themselves and to show that they are assuming their responsibility, they willingly describe it as 'free'.

  20. Environmental and deteriorating state analyses of the watershed Riacho do Tronco, Boa Vista, PB, Brazil

    Directory of Open Access Journals (Sweden)

    Ronildo Alcântara Pereira

    2010-04-01

    Full Text Available This study proposes, from the subdivision of the watershed of Riacho do Tronco in eight sub-watersheds, to diagnose their potential for land use and occupation, determine the areas of conflicts in land use and the level of environmental deterioration of the watershed as a whole, to support planning and the consequent reduction of the expansion of desertification. Based on GIS analysis and field work, the environmental parameters that allowed the establishment of the roughness coefficient of each sub-watershed were calculated, following the methodology proposed by Rocha (1997 for the classification of the natural potential use of each watershed. The results showed that four sub-watersheds are suitable for agriculture, three for livestock and reforestation and one for reforestation only. It was also possible to diagnose land use and occupation of each one and to determine land use conflicts. This represented by inappropriate use of soil considering the natural vocation of some sub-watershed, as well as the occurrence of bare soil and mining activities that occur in some sub-watersheds. Thus, from the analysis of conflict in land use, areas to be afforested, availability for or intense use of agricultural lands and the estimate of areas where correct management practices have to be implemented, it was observed that the watershed of Riacho do Tronco has 42.7% of its area in deteriorated stage. Therefore, the high level of environmental deterioration is evident, with consequent risk of desertification. In addition, considering that this area is located in the Brazilian semi-arid region with economic activities practiced without conservation concerns, it is necessary that the government and organized society foster sustainable principles in the economic activities in this watershed.

  1. BOA: Asbestos pipe-insulation removal robot system, Phase 2. Topical report, January--June 1995

    Energy Technology Data Exchange (ETDEWEB)

    Schempf, H.; Bares, J.E.

    1995-06-01

    This report explored the regulatory impact and cost-benefit of a robotic thermal asbestos pipe-insulation removal system over the current manual abatement work practice. The authors are currently in the second phase of a two-phase program to develop a robotic asbestos abatement system, comprised of a ground-based support system (including vacuum, fluid delivery, computing/electronics/power, and other subsystems) and several on-pipe removal units, each sized to handle pipes within a given diameter range. The intent of this study was to (i) aid in developing design and operational criteria for the overall system to maximize cost-efficiency, and (ii) to determine the commercial potential of a robotic pipe-insulation abatement system.

  2. Porque é Tão Difícil Ter Boas Escolas

    OpenAIRE

    Satar, Edma A.

    2010-01-01

    Nesta recensão crítica do livro do autor Larry Cuban pretende-se, em primeiro lugar, destacar as preocupações do autor da reforma educativa do sistema americano, através da implantação das tecnologias de informação e comunicação, com a distribuição de microcomputadores nas salas de aula destinados ao desenvolvimento da aprendizagem dos alunos do ensino elementar. Descreve-se o ambiente polí...

  3. Boas práticas no recrutamento especializado nas redes sociais

    OpenAIRE

    Silva, Marlene

    2011-01-01

    O processo de Recrutamento tem sofrido alterações, tornando-se mais sofisticado, envolvendo toda a organização e também a toda a comunidade. Para além das fontes de recrutamento tradicionais (jornais, universidades, escolas, entre outros), assistimos à utilização das redes sociais enquanto fonte de potenciais candidatos e futuros colaboradores. Com a Web 2.0, através das redes sociais, surgiu uma forma ainda mais fácil para as organizações conseguirem atrair potenciais colaboradores, oferecen...

  4. Wie se grond koop Boas (Rut 4:9)?/Whose land did Boaz buy (Ruth ...

    African Journals Online (AJOL)

    According to the laws and customs in the times of the judges, however, a widow was not allowed to inherit land from her husband, and a woman was not allowed to own, buy or sell land. In this article the following possibilities are investigated: Either the writer of the Ruth narrative was so far removed from the time of Ruth ...

  5. estudo comparativo entre sujeitos com boa e má qualidade do sono

    OpenAIRE

    Vicente, Sónia Lisete Pacheco

    2009-01-01

    Dissertação de Mestrado apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Psicologia, especialização em Psicologia Clínica e da Saúde. Resumo: O Sono é um bem precioso, indispensável a um bom equilíbrio. A vida de cada pessoa é uma série de ritmos que influenciam e regulam a função fisiológica e as respostas comportamentais. Desde muito cedo, é possível transmitir às crianças o prazer de dormir e os bons hábitos. Isto é quase g...

  6. Prevalência de Cryptosporidium serpentis em serpentes de cativeiro Prevalence of Cryptosporidium serpentis in captive snakes

    Directory of Open Access Journals (Sweden)

    Paulo Custório Ruggiero

    2011-11-01

    Full Text Available Cryptosporidium é um protozoário encontrado em uma grande variedade de espécies animais como responsável por casos de gastrite e enterite, porém com epidemiologia pouco conhecida em animais silvestres. A presente investigação teve como objetivo avaliar a prevalência de Cryptosporidium serpentis em lavado gástrico de serpentes mantidas em cativeiro no serpentário do Instituto Butantan (São Paulo, Brasil. A coleta foi realizada uma semana após alimentação, evitando, assim, a regurgitação devido à manipulação. Foram realizados esfregaços do sedimento do lavado gástrico, obtido por centrifugação, corados pela técnica de coloração de Kinyoun. Parte do sedimento foi submetido à técnica de RFLP-PCR para identificação da espécie de Cryptosporidium. O serpentário é dividido em três seções, por espécie - a primeira com oito jibóias (Boa constrictor amarali, a segunda com dez jararacas (Bothropoides jararaca e a última com sete cascavéis (Caudisona durissa. A prevalência de C. serpentis encontrada neste estudo para as serpentes C. durissa, B. jararaca e Boa c. amarali, foi de 57,14% (04/07, 40% (04/10 e 37,5% (03/08, respectivamente, revelando importante ocorrência desse protozoário em serpentes de cativeiro. Apesar da alta prevalência encontrada, apenas as jiboias apresentaram sintomas como perda de peso e regurgitação, refletindo uma sensibilidade diferente da espécie para C. serpentis.Cryptosporidium is a protozoan found in a wide variety of animal species which is responsible for gastritis and enteritis, but its epidemiology is poorly known in wild animals. The present investigation aimed to evaluate the prevalence of Cryptosporidium serpentis in gastric aspirate of captive snakes from the public serpentarium of the Butantan Institute (São Paulo, Brazil. Sampling was performed preferably one week after feeding, thereby preventing regurgitation due to manipulation. Smears were done from the gastric

  7. The life-cycle and ultrastructure of Sarcocystis ameivamastigodryasi n. sp., in the lizard Ameiva ameiva (Teiidae and the snake Mastigodryas bifossatus (Colubridae(1

    Directory of Open Access Journals (Sweden)

    Lainson R.

    2000-12-01

    Full Text Available Sarcocysts in muscles of the teiid lizard Ameiva ameivafrom north Brazil were fed to the colubrid snake Mastigodryas bifossatus, the faeces of which had been shown to be devoid of coccidial oocysts or sporocysts. When necropsied 16 days later the snake was shown to have developed a massive intestinal infection of Sarcocystis. Mature sporocysts from another, naturally infected M. bifossatus were fed to juvenile specimens of A. ameiva in which no sarcocysts could be detected in tail muscle biopsies. When examined 30 and 47 days later they had very large numbers of sarcocysts in their tail and tongue muscles. The parasite is given the name of Sarcocystis ameivamastigodryasi n. sp. An ultrastructural study has been made of the sarcocyst and of the parasite's sporulation in the lamina propria of the snake: the latter provides details of the wall formation process in developing sporocysts. Attempts to infect a specimen of the boid Boa constrictor constrictor by feeding it with infected Ameivafailed, suggesting that sporocysts previously recorded in genera of the family Boidae may be those of a different species of Sarcocystis.

  8. Implementación de guías de buenas prácticas clínicas elaboradas por Registered Nurses Association of Ontario (RNAO en el curriculum de Enfermería Universidad de Chile / Implementation of Clinical Best Practice Guidelines Done by The Registered Nurses’ Association of Ontario (RNAO in the Nursing Curriculum at Universidad de Chile / Implementação de manuais de boas práticas clínicas desenvolvidas por Registered Nurses Association of Ontario (RNAO no currículo de Enfermagem da Universidade do Chile

    Directory of Open Access Journals (Sweden)

    Amalia Silva-G, Lic. en Enf. y Obstetricia, Mg., PhD. (c

    2015-03-01

    evidências para a prática clínica, sendo os mais beneficiados aqueles que necessitam dos cuidados e as instituições ao ver reduzidos os seus custos. Para alcançar este objetivo, é essencial a formação permanente de profissionais de saúde e, além disto, as instituições de formação devem incluir nos seus programas de treinamento tais conteúdos. Objetivo: Este artigo apresenta a experiência de implementação de quatro manuais de boas práticas clínicas desenvolvidas pela Registered Nurses Association of Ontario (RNAO em dois programas de formação desenvolvidos no Departamento / Escola de Enfermagem da Universidade do Chile para profissionais de enfermagem. Metodologia: Para a metodologia de implementação foi considerado como um quadro de referência os materiais desenvolvidos para este fim pela organização RNAO chamado "Recursos para Professores" fundamentado nos modelos de desenvolvimento e progressão da aprendizagem como é o modelo Patricia Benner para o desenvolvimento da hipótese de progressão de conteúdos no currículo de Enfermagem e a pirâmide Miller para avaliação de competências. Conclusão: Espera-se que os alunos, ao finalizarem sua formação, adquiram as ferramentas implementadas no âmbito desta metodologia que lhes permitam um desempenho profissional fundamentado nos cuidados de enfermagem baseada na evidência científica. [Silva-G A. Implementação de manuais de boas práticas clínicas desenvolvidas por Registered Nurses Association of Ontario (RNAO no currículo de Enfermagem da Universidade do Chile. MedUNAB 2015; 17(3: xx-xx].

  9. Effects of dietary fish oil replacement by vegetable oil on the digestive enzymes activity and intestinal morphology in Meagre, Argyrosomus regius (Asso, 1801

    Directory of Open Access Journals (Sweden)

    Fernando Antunes Magalhães

    2014-07-01

    The results were analyzed by three way factorial. Amylase activity was bigger in FO when compared with VO (Table 1. The same result was observed in chymotrypsin activity. On the other hand, lipase activity was higher in VO. Regarding the levels of lipids, diets with 17% had higher amylase activity than diets with 12%. The inverse was observed in chymotrypsin activity. In relation to lipase activity, no differences were observed on the two levels of lipids studied. No differences in digestive enzymes activities were observed when diets were supplemented with selenium. Epithelium architecture of the posterior intestine was slightly affected by dietary treatments. Higher levels of lipids seem to induce enterocyte vacuolization, and vacuoles seem to be larger when a blend of vegetable oils was used instead of fish oil. No clear role can be attributed to selenium regarding intestinal morphology. In conclusion, our study showed that the source and levels of lipid in diets for meagre have influence in activity of digestible enzymes like amylase, lipase and chymotrypsin. Furthermore, levels of selenium do not cause an alteration in studied digestible enzymes.

  10. Dose-dependent effect of a single GnRHa injection on the spawning of meagre (Argyrosomus regius broodstock reared in captivity

    Directory of Open Access Journals (Sweden)

    Hipolito Fernandez-Palacios

    2014-10-01

    Full Text Available The present study aimed to determine the spawning efficacy, egg quality and quantity of captive breed meagre induced with a single gonadotrophin‐releasing hormone agonist (GnRHa injection of 0, 1, 5, 10, 15, 20, 25, 30, 40 or 50 µg kg-1 to determine a recommended optimum dose to induce spawning. The doses 10, 15 and 20 μg kg-1 gave eggs with the highest quality (measured as: percentage of viability, floating, fertilisation and hatch and quantity (measured as: total number of eggs, number of viable eggs, number of floating eggs, number of hatched larvae and number of larvae that reabsorbed the yolk sac. All egg quantity parameters were described by Gaussian regression analysis with R2=0.89 or R2=0.88. The Gaussian regression analysis identified that the optimal dose used was 15 μg kg-1. The regression analysis highlighted that this comprehensive study examined doses that ranged from low doses insufficient to stimulate a high spawning response (significantly lower egg quantities, p<0.05 compared to 15 μg kg-1 through to high doses that stimulated the spawning of significantly lower egg quantities and eggs with significantly lower quality (egg viability. In addition, the latency period (time from hormone application to spawning decreased with increasing doses to give a regression (R2=0.93 which suggests that higher doses accelerated oocyte development that in turn reduced egg quality and quantity. The identification of an optimal dose for the spawning of meagre, which has high aquaculture potential, represents an important advance for the Mediterranean aquaculture industry.

  11. Reptile-associated ticks from Dominica and the Bahamas with notes on hyperparasitic erythraeid mites.

    Science.gov (United States)

    Durden, Lance A; Knapp, Charles R; Beati, Lorenza; Dold, Stephanie

    2015-02-01

    Ticks were collected or recorded from 522 individual reptiles on Dominica and from 658 reptiles from the Bahamas. Two species of ticks were collected on Dominica: Amblyomma antillorum and Amblyomma rotundatum. Similarly, 2 species were collected in the Bahamas: Amblyomma albopictum and Amblyomma torrei. On Dominica, A. antillorum was recorded from 517 Lesser Antillean iguanas (Iguana delicatissima), 2 boa constrictors (Boa nebulosa), 1 Antilles snake (Alsophis sibonius), and 1 Dominican ground lizard (Ameiva fuscata), whereas A. rotundatum was recorded from 1 Lesser Antillean skink (Mabuya mabouya). In the Bahamas, A. albopictum was recorded from 131 Andros iguanas (Cyclura cychlura cychlura), 271 Exuma Island iguanas (Cyclura cychlura figginsi), and 1 Andros curlytail lizard (Leiocephalus carinatus coryi), whereas A. torrei was recorded from 255 Exuma Island iguanas. In the Bahamas, A. albopictum parasitized iguanas on Andros Island and the central Exuma Islands, and A. torrei parasitized iguanas in the southern Exumas. An exception to this trend was that A. torrei was collected from iguanas on Pasture Cay in the central Exumas, an anomaly that is explained by the fact that iguanas (with attached ticks) on Pasture Cay were introduced by humans in the past from islands further south. External hyperparasitic larval erythraeid mites ( Leptus sp.) were recorded from A. torrei in the Bahamas.

  12. Snakes mimic earthworms: propulsion using rectilinear travelling waves

    Science.gov (United States)

    Marvi, Hamidreza; Bridges, Jacob; Hu, David L.

    2013-01-01

    In rectilinear locomotion, snakes propel themselves using unidirectional travelling waves of muscular contraction, in a style similar to earthworms. In this combined experimental and theoretical study, we film rectilinear locomotion of three species of snakes, including red-tailed boa constrictors, Dumeril's boas and Gaboon vipers. The kinematics of a snake's extension–contraction travelling wave are characterized by wave frequency, amplitude and speed. We find wave frequency increases with increasing body size, an opposite trend than that for legged animals. We predict body speed with 73–97% accuracy using a mathematical model of a one-dimensional n-linked crawler that uses friction as the dominant propulsive force. We apply our model to show snakes have optimal wave frequencies: higher values increase Froude number causing the snake to slip; smaller values decrease thrust and so body speed. Other choices of kinematic variables, such as wave amplitude, are suboptimal and appear to be limited by anatomical constraints. Our model also shows that local body lifting increases a snake's speed by 31 per cent, demonstrating that rectilinear locomotion benefits from vertical motion similar to walking. PMID:23635494

  13. Chemerin Elicits Potent Constrictor Actions via Chemokine-Like Receptor 1 (CMKLR1), not G-Protein-Coupled Receptor 1 (GPR1), in Human and Rat Vasculature.

    Science.gov (United States)

    Kennedy, Amanda J; Yang, Peiran; Read, Cai; Kuc, Rhoda E; Yang, Lucy; Taylor, Emily J A; Taylor, Colin W; Maguire, Janet J; Davenport, Anthony P

    2016-10-14

    Circulating levels of chemerin are significantly higher in hypertensive patients and positively correlate with blood pressure. Chemerin activates chemokine-like receptor 1 (CMKLR1 or ChemR23) and is proposed to activate the "orphan" G-protein-coupled receptor 1 (GPR1), which has been linked with hypertension. Our aim was to localize chemerin, CMKLR1, and GPR1 in the human vasculature and determine whether 1 or both of these receptors mediate vasoconstriction. Using immunohistochemistry and molecular biology in conduit arteries and veins and resistance vessels, we localized chemerin to endothelium, smooth muscle, and adventitia and found that CMKLR1 and GPR1 were widely expressed in smooth muscle. C9 (chemerin149-157) contracted human saphenous vein (pD 2 =7.30±0.31) and resistance arteries (pD 2 =7.05±0.54) and increased blood pressure in rats by 9.1±1.0 mm Hg at 200 nmol. Crucially, these in vitro and in vivo vascular actions were blocked by CCX832, which we confirmed to be highly selective for CMKLR1 over GPR1. C9 inhibited cAMP accumulation in human aortic smooth muscle cells and preconstricted rat aorta, consistent with the observed vasoconstrictor action. Downstream signaling was explored further and, compared to chemerin, C9 showed a bias factor=≈5000 for the G i protein pathway, suggesting that CMKLR1 exhibits biased agonism. Our data suggest that chemerin acts at CMKLR1, but not GPR1, to increase blood pressure. Chemerin has an established detrimental role in metabolic syndrome, and these direct vascular actions may contribute to hypertension, an additional risk factor for cardiovascular disease. This study provides proof of principle for the therapeutic potential of selective CMKLR1 antagonists. © 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

  14. COMERCIO DE FAUNA SILVESTRE EN COLOMBIA WILDLIFE TRADE IN COLOMBIA

    Directory of Open Access Journals (Sweden)

    Néstor Javier Mancera Rodríguez

    2008-12-01

    Full Text Available Este trabajo ofrece un panorama sobre las actividades relacionadas con el comercio de bienes derivados de las especies de fauna silvestre en Colombia, abordando el tema desde el desarrollo que ha tenido su actividad productiva, el aprovechamiento extractivo, así como la dinámica de su comercio legal e ilegal en el país y el desarrollo y promoción de alternativas productivas sustentadas en su aprovechamiento. Se analizó la información secundaria de entidades como el Ministerio de Ambiente, Vivienda y Desarrollo Territorial, las Corporaciones Autónomas Regionales y Autoridades Ambientales Urbanas, el Instituto Colombiano de Desarrollo Rural-INCODER, las Autoridades Policiales, los Institutos de Investigación, el Departamento Administrativo Nacional de Estadística, la Dirección de Impuestos y Aduanas Nacionales-DIAN, el Ministerio de Comercio, Industria y Turismo, y PROEXPORT. entre otras. En Colombia, el comercio de especies de fauna silvestre está centrado principalmente en la extracción de ejemplares de forma ilegal, lo cual ha generado desequilibrios en las poblaciones naturales y ha repercutido en el deterioro de la dinámica de los ecosistemas. El comercio legal de fauna silvestre se basa en la producción de unas pocas especies entre las que se destacan la babilla (Caiman crocodilus, el chigüiro (Hydrochaeris hydrochaeris, cerca de 200 especies de peces ornamentales y en menor medida el lobo pollero (Tupinambis nigropunctatus, la iguana (Iguana iguana, la boa (Boa constrictor, escarabajos (Dynastes hercules y mariposas. En el país no se tiene información exacta sobre el número de incautaciones realizadas en los operativos de control al tráfico ilegal de fauna, y no existe un conocimiento de la dinámica de este comercio ilegal.This work offers a current view on the activities related to the trade of derived from the wildlife species in Colombia, approaching the topic from the development that has had its productive activity

  15. Boa noite, e boa sorte: determinantes da demissão de ministros envolvidos em escândalos de corrupção no primeiro governo Dilma Rousseff

    Directory of Open Access Journals (Sweden)

    Cletiane Medeiros Araújo

    2016-04-01

    Full Text Available Resumo Quais os determinantes para demissão de ministros? Este artigo analisa a onda de escândalos de corrupção envolvendo ministros do primeiro governo Dilma Rousseff. O desenho de pesquisa combina estatística descritiva e análise multivariada para testar as hipóteses de que notícias sobre escândalos políticos, competição política e gerenciamento da coalizão impactam positivamente na probabilidade de o ministro denunciado deixar a pasta ministerial. O estudo foi realizado a partir da construção de uma base de dados, para a qual foram coletadas 677 notícias de três jornais de larga circulação nacional, a saber: Folha de S. Paulo, O Estado de S. Paulo e O Globo, ao longo dos 17 primeiros meses do governo. Os resultados apontam que quanto maior o número de matérias sobre os escândalos de corrupção do ministro denunciado maior a probabilidade de ele ser demitido. Espera-se, através deste estudo de caso, contribuir para a agenda de pesquisa sobre a relação escândalos políticos/instituições democráticas/accountability, buscando situar esse fenômeno na democracia brasileira recente.

  16. Meninas bem-comportadas, boas alunas; meninos inteligentes, indisciplinados Good girls, good students; smart boys but misbehaved

    Directory of Open Access Journals (Sweden)

    Cármen A. Duarte da Silva

    1999-07-01

    Full Text Available Estudo longitudinal vem acompanhando todas as crianças nascidas em Pelotas, Rio Grande do Sul, no ano de 1982. Suas trajetórias escolares mostraram-se fortemente determinadas pela variável gênero, mesmo quando eliminados por estatística outros fatores intervenientes. Um estudo com 84 professoras/es buscou identificar que processos estão presentes na escola e nas representações que ajudem a compreender essas diferenças no desempenho escolar das meninas e dos meninos. A análise do material aponta para a maneira feminina de exercer o magistério que atravessa a prática docente, para a profecia auto-realizadora referendada no critério de bom comportamento e para a estreita relação entre gênero e saber regulados pelos regimes de verdade.A longitudinal study has been following all the children born in Pelotas, Rio Grande do Sul, during 1982. Their academic background showed strong correlation with gender, even when eliminating other variables through statistical procedures. A study with 84 teachers tried to identify the process present at schools that could help to understand the differences between the girls' and boys' academic performances. The analysis points out to the female bias in teaching practice, to the self-fulfilling profecy reflected in the good-behavior criterion and to the close relationship between gender and knowledge determinated by the truth-regulations.

  17. Habilidades de leitura e escrita de crianças disléxicas e boas leitoras

    Directory of Open Access Journals (Sweden)

    Katerina Lukasov

    2014-09-01

    Full Text Available The work aims to assess the abilities of reading and writing in dyslexic and normal children through the following tests: Sentence Reading Comprehension Test (SRCT, of Sentence Hearing Comprehension Test (SHCT, of Picture-Print Writing Test (PPWT 1.1-Writing, of Picture-Print Matching Test (PPMT 1.1-Choice and Word Reading Competence Test (WRCT. 10 dyslexic children and 10 controls composed the sample. Significant differences was founded in performance of dyslexics in TTWT 1.1-Writing, TTWT 1.1-Choice and WRCT, with inferior performance in relation to the controls. Pearson’s correlations show that children with good performance in WRCT also had good performance in TTWT 1.1-Writing. The execution time of SRCT was raised in the group of dyslexics, but the number of rightness if kept in the average of the control group. These results allows to assess the effectiveness of the methods of evaluation, education and intervention of the pertaining to school tasks in dyslexics, therefore some dyslexics can have equal or superior performance to the one of the reading good children in case that she has the time necessary and enough to carry through its tasks

  18. Purple Boas, Lesbian Affection, and John Deere Hats: Teacher Educators' Role in Addressing Homophobia in Secondary Schools

    Science.gov (United States)

    Jones, Joseph R.

    2014-01-01

    This article examines how one group of teachers discussed their perceptions of homophobia in their schools. A qualitative study was conducted that utilized the following: individual and group interviews, participant reflective journals, professional development sessions, and a research journal. The study illuminated how the role of hegemonic…

  19. Realization of CGI Technique Based on μClinux Boa%基于μClinux下Boa的CGI技术实现

    Institute of Scientific and Technical Information of China (English)

    宋丽娟; 董小国

    2009-01-01

    在传统的CGI程序编写中,用printf()函数产生HTML源代码,这样的CGI程序代码冗长,不利于阅读,且容易出错.针对这一问题,提出仿"ASP"技术的解决方法,即预先将需要显示的同页保存成文件,并设计配置文件将需要动态显示的内容进行替换.实验表明,该方法可显著减少CGI程序代码量,且便于修改升级.另外通过修改Web服务器Boa的源代码,对文件路径进行隐藏,增加了系统的安全性.

  20. Basic model of quality and good practices in neonatal radiography; Modelo basico de qualidade e boas praticas em radiografia neonatal

    Energy Technology Data Exchange (ETDEWEB)

    Dias, Janine H.; Goulart, Juliana M.; Lykawka, Rochelle; Bacelar, Alexandre [Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, RS (Brazil)

    2016-07-01

    Neonatal chest radiographs were evaluated and 3 variables were analyzed: collimation, positioning and presence of artifacts. This study is a pilot for develop a model of good practices in radiology, which is in development phase. The index of analyzed radiographs considered inadequate is expressive and it shows the need for a model that may be part of an optimization program to medical exposures. (author)

  1. Apresentação sobre boas práticas editoriais para os editores científicos - UNINOVE

    OpenAIRE

    Silva, Altieres de Oliveira; Maccari, Emerson

    2015-01-01

    Com base nas discussões que foram apresentadas no Curso de Editoração Cientifica da Associação Brasileira de Editores Cientificos - ABEC, esta apresentação teve como objetivo orientar/ajudar os editores cientificos dos periódicos em Administração -UNINOVE. Contemplando os seguintes aspectos: gestão editorial; indexação; diretrizes para os autores; fator de impacto; redes sociais para alavancar a visibidade dos periódicos e artigos.

  2. Tópicos para uma boa análise de dados de estudos empíricos

    Directory of Open Access Journals (Sweden)

    Teresa Garcia-Marques

    2014-08-01

    Full Text Available Este artigo discute o processo de análise de dados em sete tópicos: a modelos estatísticos, técnicas estatísticas e diferenciação de "receita estatística"; b a associação da validade das conclusões estatísticas ao processo de delineamento e amostragem; c a diferença e complementaridade da descrição de dados e do teste de hipóteses; d como as hipóteses se relacionam com os testes estatísticos a realizar; e a análise preliminar de dados e sua relevância; f teste de hipótese na perspectiva de Fisher e de Neyman e Pearson; g a apresentação dos dados como um processo comunicacional, e vantagens do uso de normas (APA.

  3. CAPACITAÇÃO DE CRIANÇAS COM DIFICULDADES INTELECTUAIS PARA BOAS PRÁTICAS ALIMENTARES

    Directory of Open Access Journals (Sweden)

    Maria Aurora Boné

    2015-07-01

    Full Text Available A obesidade é considerada pela Organização Mundial de Saúde uma epidemia do século XXI. Existe evidência científica suficientemente forte que associa as práticas alimentares à obesidade. Os estudos acerca dos hábitos alimentares entre a população com necessidades educativas especiais escasseiam, em Portugal. Este trabalho parte do pressuposto que a capacitação de pessoas com dificuldades intelectuais contribui favoravelmente para as suas escolhas alimentares. Desenvolveu-se com seis alunas institucionalizadas, do terceiro ciclo do ensino básico português, com dificuldades intelectuais, de um agrupamento de escolas do distrito de Portalegre (Portugal, no ano letivo de 2013/2014. Fez-se avaliação antropométrica e observação não participante dos sujeitos, relativamente aos seus hábitos e às suas práticas alimentares, em ambiente escolar. A análise da informação permitiu elaborar um plano de capacitação para escolhas alimentares saudáveis, desenvolvido em função da especificidade de cada sujeito. Os resultados apontam para uma alteração nos comportamentos alimentares no período imediatamente decorrente à implementação do programa de capacitação.

  4. O ACOLHIMENTO COMO BOA PRÁTICA NA ATENÇÃO BÁSICA À SAÚDE

    Directory of Open Access Journals (Sweden)

    Patricia Guerrero

    2013-01-01

    Full Text Available Se objetivó comprender el acogimiento como buena práctica de salud en la atención primaria, tras la percepción de gerentes, profesionales y usuarios, teniendo en cuenta las dimensiones diálogo, postura y reorganización de los servicios. Es una investigación descriptiva-analítica, de naturaleza cualitativa y marco teórico-metodológico de la Teoría Fundamentada. Se obtuvieron los datos a partir de entrevistas con siete coordinadores, diez profesionales y doce usuarios de centros de salud de Florianópolis-SC. En vista de las buenas prácticas, el acogimiento se convierte en un punto de intersección entre los diferentes sujetos y las prácticas de cuidado en atención primaria en el desarrollo de las dimensiones acogimiento-diálogo, acogimiento-postura, y acogimiento-reorganización de los servicios. El acogimiento provoca cambios en el proceso de trabajo, en las relaciones establecidas y en la organización de los servicios. La interconexión de la tríada reconfigura las acciones y contribuye a la consolidación de este modelo de atención.

  5. Comunicación química en la boa arco iris Epicrates cenchria alvarezi (Serpentes, Boidae

    Directory of Open Access Journals (Sweden)

    Briguera, Verónica

    1994-01-01

    Full Text Available In snakes there are two possible pheromonal sources: skin and cloacal glands. In this work, we tested both secretions in adults of Epicrates cenchria alvarezi as messages transmitters, trying to explain the role that plays this information in the social context of this species. Both secretions have shown to have pheromonal function. Conespecific odors elicited more tongue extrusions than other stimuli did. These results suggest that the snake is capable of discriminating conspecifics based on chemical cues alone.

  6. Molecular cloning and characterization of satellite DNA sequences from constitutive heterochromatin of the habu snake (Protobothrops flavoviridis, Viperidae) and the Burmese python (Python bivittatus, Pythonidae).

    Science.gov (United States)

    Matsubara, Kazumi; Uno, Yoshinobu; Srikulnath, Kornsorn; Seki, Risako; Nishida, Chizuko; Matsuda, Yoichi

    2015-12-01

    Highly repetitive DNA sequences of the centromeric heterochromatin provide valuable molecular cytogenetic markers for the investigation of genomic compartmentalization in the macrochromosomes and microchromosomes of sauropsids. Here, the relationship between centromeric heterochromatin and karyotype evolution was examined using cloned repetitive DNA sequences from two snake species, the habu snake (Protobothrops flavoviridis, Crotalinae, Viperidae) and Burmese python (Python bivittatus, Pythonidae). Three satellite DNA (stDNA) families were isolated from the heterochromatin of these snakes: 168-bp PFL-MspI from P. flavoviridis and 196-bp PBI-DdeI and 174-bp PBI-MspI from P. bivittatus. The PFL-MspI and PBI-DdeI sequences were localized to the centromeric regions of most chromosomes in the respective species, suggesting that the two sequences were the major components of the centromeric heterochromatin in these organisms. The PBI-MspI sequence was localized to the pericentromeric region of four chromosome pairs. The PFL-MspI and the PBI-DdeI sequences were conserved only in the genome of closely related species, Gloydius blomhoffii (Crotalinae) and Python molurus, respectively, although their locations on the chromosomes were slightly different. In contrast, the PBI-MspI sequence was also in the genomes of P. molurus and Boa constrictor (Boidae), and additionally localized to the centromeric regions of eight chromosome pairs in B. constrictor, suggesting that this sequence originated in the genome of a common ancestor of Pythonidae and Boidae, approximately 86 million years ago. The three stDNA sequences showed no genomic compartmentalization between the macrochromosomes and microchromosomes, suggesting that homogenization of the centromeric and/or pericentromeric stDNA sequences occurred in the macrochromosomes and microchromosomes of these snakes.

  7. Reactividad inmunoquímica de sueros anti- Caiman yacare y Caiman latirostris frente a sueros de diferentes especies

    Directory of Open Access Journals (Sweden)

    de Roodt, Adolfo Rafael

    2010-06-01

    Full Text Available Se estudió la reactividad inmunoquímica entre los sueros de distintas especies de reptiles frente a sueros hiperinmunes experimentales anti-suero de Caiman yacare y anti-suero de Caiman latirostris. Los sueros que se probaron fueron los homólogos de Caiman yacare, Caiman latirostris y los heterólogos de Alligator missisipiensis, Tupinambis merinae, Tupinambis rufescens, Chelonoidis chilensis, Clelia rustica, Waglerophis merremii, Lystrophys dorbignyi, Phyton molurus, Boa constrictor occidentalis, Eunectes notaeus, Crotalus durissus terrificus, Bothrops alternatus, Bothrops diporus, Bothrops jararaca, Bothrops jararacussu, Bothrops moojeni, Pitangus sulphuratus y Gallus gallus. La reactividad inmunoquímica se determinó mediante las técnicas de doble inmunodifusión y ELISA, mostrándose importante entre los sueros de los crocodrílidos y baja entre estos y los de las otras especies de reptiles estudiadas. Se observó mayor reactividad entre los antisueros anti-Caiman respecto a los sueros de Caiman latirostris y Caiman yacare que frente al suero de Alligator missisipiensis. Además, se encontró una fuerte reactividad entre ambos sueros anti-Caiman y el de Gallus gallus poniendo en evidencia la fuerte reactividad entre los sueros de arcosaurios. In order to study the immunochemical reactivity among sera from different species of reptiles regarding sera from Caiman, the immunoreactivity of sera from reptiles against antisera to Caiman yacare or anti-Caiman latirostris sera was studied. These hiperimmune sera were tested against sera from Alligator missisipiensis, Tupinambis merinae, Tupinambis rufescens, Chelonoidis chilensis, Clelia rustica, Waglerophis merremii, Lystrophys dorbignyi, Phyton molurus, Boa constrictor occidentalis, Eunectes notaeus, Crotalus durissus terrificus, Bothrops alternatus, Bothrops neuwiedii, Bothrops jararaca, Bothrops jararacussu, Bothrops moojeni, Pitangus sulphuratus and Gallus gallus. The immunochemical

  8. Morphologic and morphometric analysis of Hepatozoon spp. (Apicomplexa, Hepatozoidae of snakes

    Directory of Open Access Journals (Sweden)

    Moço Tatiana Cristina

    2002-01-01

    Full Text Available Hepatozoon species are the most abundant hemoparasites of snakes. Its identification has been based mainly on the morphologic characterization of the gamonts in the peripheral blood of the vertebrate host and also of the cysts found in the internal organs of the vertebrate and invertebrate hosts. Using a computerized image analysis system, we studied five species of Hepatozoon from recently captured snakes in Botucatu, State of São Paulo, Brazil, to evaluate the importance of the morphology and morphometry of the gamonts for the characterization of Hepatozoon species and to analyze the morphologic changes induced in the erythrocytes by the parasite. The studied species were H. terzii of Boa constrictor amarali, Hepatozoon sp. of Crotalus durissusterrificus, H. philodryasi of Philodryas patagoniensis, and H. migonei and H. cyclagrasi of Hydrodynastes gigas. We observed three different groups, one of them including the species H. terzii, H. philodryasi and Hepatozoon sp. of C. durissus terrificus; and the other two consisting of H. migonei and H. cyclagrasi. Degree of alterations in the erythrocytes was variable and it may be useful for characterization of Hepatozoon species.

  9. Ticks on captive and free-living wild animals in northeastern Brazil.

    Science.gov (United States)

    Dantas-Torres, Filipe; Ferreira, Débora R A; de Melo, Louise M; Lima, Polly-Ana C P; Siqueira, Daniel B; Rameh-de-Albuquerque, Luciana C; de Melo, Adriana V; Ramos, Janaina A C

    2010-02-01

    From 2005 to 2009, 147 ticks found on 32 wild animals from or referred to two zoobotanical parks (Parque Zoobotânico Arruda Câmara and Parque Estadual Dois Irmãos) located in northeastern Brazil were identified. Ticks found on two veterinarians working in one of the parks (i.e., Parque Estadual Dois Irmãos), after return from forested areas within the park's territory, were also identified. The following tick-host associations were recorded: Amblyomma fuscum Neumann on Boa constrictor L.; Amblyomma longirostre Koch on Ramphastos vitellinus ariel Vigors and Coendou prehensilis (L.); Amblyomma varium Koch on Bradypus variegates Schinz; Amblyomma rotundatum Koch on Chelonoidis carbonaria (Spix), Chelonoidis denticulata (L.), Micrurus ibiboboca (Merrem), Python molurus bivittatus Kuhl, Iguana iguana (L.) and B. variegatus; Amblyomma nodosum Neumann on Myrmecophaga tridactyla L. and Tamandua tetradactyla (L.); and Rhipicephalus sanguineus (Latreille) on Nasua nasua (L.). The ticks found on the veterinarians were identified as nine Amblyomma larvae. The presence of Am. nodosum in Pernambuco and Am. rotundatum and Am. varium in Paraíba is recorded for the first time and the occurrence of Am. longirostre in Pernambuco is confirmed. Ramphastos vitellinus ariel is a new host record for Am. longirostre whereas M. ibiboboca and B. variegatus are new host records for Am. rotundatum. Finally, the human parasitism by Amblyomma ticks is reported for the first time in Pernambuco, highlighting the potential of tick-borne pathogen transmission in this state.

  10. Anti-Leptospira spp. antibodies in captive animals in Paraíba State

    Directory of Open Access Journals (Sweden)

    Arthur Brasil

    2013-12-01

    Full Text Available The aim of this survey was to verify the occurrence of anti-Leptospira spp. antibodies in captive animals in the Parque Zoobotânico Arruda Câmara, João Pessoa, Paraíba State, Northeastern Brazil. Blood samples were collected from 49 animals: 26 mammals of the species Sapajus libidinosus, Cebus flavius, Saimiri sciureu, Coendu sp., Pseudalopex vetulus, Leopardus pardalis, Leopardus tigrinus, Galactitis vitata, Eira barbara, Nasua nasua, Tayassu tajacu and Ratus norvegicus; 10 birds of the species Penelope jacucaca, Pavo cristatus, Anodorhynchus hyacinthinus, Ara chlorothpterus, Pionites leucogaster, Polyborus plancus, Geranoaetus melanoleucus and Urubitinga urubitinga; and 13 reptiles of the species Caiman latirostris, Paleosuchus trigonatus, Caiman crocodilus, Tupinabis merinae, Tupinambis teguixin, Boa constrictor, Corallus hortulanus, Python molurus, Bufocephala vanderhaegei, Geochelone denticulata and Geochelone carboraria. Sera were examined by the microscopic agglutination teste (MAT using 24 serovars as antigens and cut-off point of 1:100. One ocelot (Leopardo pardalis presented positive reaction for the Icterohaemorrhagiae serovar with titer of 100, however, it did not show any clinical sign of the infection. Sinantropic rodents are the main reservoirs of this serovar, which suggests the need of maintenance and continuous evaluation of rodent control programs.

  11. Traditional uses of medicinal animals in the semi-arid region of northeastern Brazil

    Directory of Open Access Journals (Sweden)

    Alves Rômulo Romeu Nóbrega

    2012-10-01

    Full Text Available Abstract The present work presents an inventory of the traditional medicinal uses of animals in the municipality of Bom Sucesso in Paraíba State (PB in the semiarid northeastern region of Brazil. Information was obtained through the use of semi-structured interviews with 50 people who use zootherapeutic products. A total of 25 animal species used for medicinal purposes were identified (18 vertebrates and seven invertebrates distributed among five taxonomic categories; the groups with the largest numbers of citations were: mammals (8 citations, insects (7, and reptiles (5. The most cited animal species were: Tubinambis merianae “teju” lizards (44 citations; Apis mellifera Italian honeybees (318 citations; Gallus gallus chickens (31 citations; Ovis aries sheep (31 citations; Crotalus durissus rattlesnakes (14 citations; Boa constrictor (12 citations; and Bos taurus cattle (12 citations. A significant number of illnesses and conditions treated with animal-based medicines were cited, and the category with the greatest number of citations was “problems affecting the respiratory system”. Our results suggest that the use of zootherapeutics in the region is persistent, and that knowledge about these curative practices is an integral part of the regional culture. As such, studies concerning the uses of zootherapeutics are important windows to understanding human/environmental/cultural interactions and a pathway to conciliating regional cultures with efforts to conserve the native fauna.

  12. Postembryonic Nephrogenesis and Persistence of Six2-Expressing Nephron Progenitor Cells in the Reptilian Kidney

    Science.gov (United States)

    Camarata, Troy; Howard, Alexis; Elsey, Ruth M.; Raza, Sarah; O’Connor, Alice; Beatty, Brian; Conrad, Jack; Solounias, Nikos; Chow, Priscilla; Mukta, Saima; Vasilyev, Aleksandr

    2016-01-01

    New nephron formation (nephrogenesis) ceases in mammals around birth and is completely absent in adults. In contrast, postembryonic nephrogenesis is well documented in the mesonephric kidneys of fishes and amphibians. The transient mesonephros in reptiles (including birds) and mammals is replaced by the metanephros during embryogenesis. Thus, one may speculate that postembryonic nephrogenesis is restricted to the mesonephric kidney. Previous reports have suggested the metanephros of non-avian reptiles (hereafter reptiles) may continually form nephrons throughout life. We investigated the presence of adult nephrogenesis in reptiles by examining adult kidneys from several species including Trachemys scripta, Chrysemys picta, Boa constrictor, Tupinambis tegu, Anolis carolinensis, and Alligator mississipiensis among others. We found that all major reptilian groups (Testudines, Crocodylia, and Squamates) showed the presence of adult nephrogenesis. The total amount of nephrogenesis varied greatly between species with turtles displaying the highest density of nephrogenesis. In contrast, we were unable to detect adult nephrogenesis in monotremes, and in the iguanid A. carolinensis. Nephron progenitor cells express the transcription factor Six2, which in mammals, becomes downregulated as the progenitor cell population is exhausted and nephrogenesis ends. Using the alligator as a model, we were able to detect Six2-positive cap mesenchyme cells in the adult kidney, which spatially correlated with areas of nephrogenesis. These results suggest that the metanephric kidney of reptiles has maintained the ability to continually grow new nephrons during postembryonic life, a process lost early in mammalian evolution, likely due to the persistence of a Six2-expressing progenitor cell population. PMID:27144443

  13. Postembryonic Nephrogenesis and Persistence of Six2-Expressing Nephron Progenitor Cells in the Reptilian Kidney.

    Science.gov (United States)

    Camarata, Troy; Howard, Alexis; Elsey, Ruth M; Raza, Sarah; O'Connor, Alice; Beatty, Brian; Conrad, Jack; Solounias, Nikos; Chow, Priscilla; Mukta, Saima; Vasilyev, Aleksandr

    2016-01-01

    New nephron formation (nephrogenesis) ceases in mammals around birth and is completely absent in adults. In contrast, postembryonic nephrogenesis is well documented in the mesonephric kidneys of fishes and amphibians. The transient mesonephros in reptiles (including birds) and mammals is replaced by the metanephros during embryogenesis. Thus, one may speculate that postembryonic nephrogenesis is restricted to the mesonephric kidney. Previous reports have suggested the metanephros of non-avian reptiles (hereafter reptiles) may continually form nephrons throughout life. We investigated the presence of adult nephrogenesis in reptiles by examining adult kidneys from several species including Trachemys scripta, Chrysemys picta, Boa constrictor, Tupinambis tegu, Anolis carolinensis, and Alligator mississipiensis among others. We found that all major reptilian groups (Testudines, Crocodylia, and Squamates) showed the presence of adult nephrogenesis. The total amount of nephrogenesis varied greatly between species with turtles displaying the highest density of nephrogenesis. In contrast, we were unable to detect adult nephrogenesis in monotremes, and in the iguanid A. carolinensis. Nephron progenitor cells express the transcription factor Six2, which in mammals, becomes downregulated as the progenitor cell population is exhausted and nephrogenesis ends. Using the alligator as a model, we were able to detect Six2-positive cap mesenchyme cells in the adult kidney, which spatially correlated with areas of nephrogenesis. These results suggest that the metanephric kidney of reptiles has maintained the ability to continually grow new nephrons during postembryonic life, a process lost early in mammalian evolution, likely due to the persistence of a Six2-expressing progenitor cell population.

  14. A incubação de empresas : boas práticas e fatores críticos de sucesso

    OpenAIRE

    Campos, João Pedro Coelho de

    2015-01-01

    Relatório de estágio do mestrado em Gestão, apresentado à Faculdade de Economia da Universidade de Coimbra, sob a orientação de Pedro Godinho e Isabel Maria Bontempo de Sá O presente relatório foi elaborado como parte integrante do Mestrado em Gestão da Faculdade de Economia da Universidade de Coimbra e pretende ser o reflexo do estágio curricular realizado no Conselho Empresarial do Centro/Câmara de Comércio e Indústria do Centro (CEC/CCIC), durante o período de 2 de fevereiro de 2015 a 2...

  15. AVALIAÇÃO DAS CONDIÇÕES HIGIÊNICO-SANITÁRIAS E DE BOAS PRÁTICAS DE FABRICAÇÃO EM PANIFICADORAS

    OpenAIRE

    Maria Fernanda CARDOSO; Viviane MIGUEL; Cíntia Alessandra Matiucci PEREIRA

    2011-01-01

    As padarias ou panifi cadoras se difundiram no Brasil a partir da colonização, quando portugueses e espanhóis trouxeram hábitos alimentares da Europa, tornando-se parte da nossa história e cultura. Hoje as padarias estão deixando de ser apenas estabelecimentos responsá- veis pela fabricação artesanal e venda de pães, e estão se transformando em centros de convivência, gastronomia e serviços. Com o crescimento populacional em algumas cidades, as pessoas buscam sempre fo...

  16. Uma "boa" morte em UTI pediátrica: é isso possível? A "good" death in a pediatric ICU: is it possible?

    Directory of Open Access Journals (Sweden)

    Daniel Garros

    2003-11-01

    Full Text Available OBJETIVO: Dentro das modernas UTIPs (unidades de terapia intensiva pediátricas existe um número elevado de casos em que a restrição ou a remoção de medidas de suporte de vida (MSV é realizada com o objetivo de permitir a morte da criança, para a qual não há mais tratamento viável. Conseqüentemente, a medicina paliativa está tomando lugar de destaque dentro da UTIP. O objetivo desta revisão é oferecer ao intensivista maneiras de prover para seu paciente uma morte digna e mais humana, dentro deste contexto. FONTES DOS DADOS: Utilizando uma revisão sistemática no banco de dados Medline, com terminologia pertinente, uma seleção de artigos pertinentes são revisados, com ênfase no tema morte em UTIP. Conceitos de medicina paliativa aplicáveis neste ambiente são introduzidos. SÍNTESE DOS DADOS: A morte digna para uma criança em cuidado paliativo dentro da UTIP pode ser alcançada, se algumas medidas simples são observadas, tais como: oportunizar à família participação em todo o processo decisório num ambiente de abertura e honestidade mútua, abrir as portas da UTI para certos rituais que a família julgar importante, oferecer privacidade, controlar efetivamente a dor e sintomas de desconforto na hora da remoção ou restrição de MSV, e proceder com remoção de MSV na presença da família, se assim ela desejar. CONCLUSÃO: A morte de uma criança em UTIP, quando resulta de restrição ou remoção de suporte de vida, pode ser dignificada e humanizada, se princípios básicos de medicina paliativa e cuidados centrados na família são trazidos para dentro deste ambiente, notadamente caracterizado como de alta tecnologia e visto pelo público como desumano.OBJECTIVES: In the modern pediatric intensive care unit (PICU physicians are often faced with the need to interrupt life-sustaining treatment (LST and to allow children to die when no further treatment options are available. Consequently, the importance of palliative care has been increasing in this context. The goal of this review is to provide intensivists with guidelines to allow PICU patients to have a more dignified and humane death. SOURCE OF DATA: Medline was searched using relevant key-words, emphasizing the topic of death in the PICU. The principles of palliative care medicine were then applied to this context. SUMMARY OF DATA: To ensure a dignified death for a child receiving palliative care in the PICU some important measures must be taken, such as: let the family participate in the decision-making process in an open and honest manner; allow family members to perform their religious rites and rituals; offer them moments of complete privacy; effectively manage pain and discomfort, especially at the time of removal of LST; and finally, let the family be present when LST is interrupted, if they so desire. CONCLUSION: A child's death following withdrawal of LST in the PICU can be humane and dignified if basic principles of palliative care are followed. This is especially important in an environment that is notorious for the use of complex technology and described by the general public as inhumane.

  17. Transplantation and Application of Embedded BOA in the Internet of Things%物联网系统中嵌入式BOA的移植与应用

    Institute of Scientific and Technical Information of China (English)

    谢华成; 李晶

    2011-01-01

    论述了物联网中嵌入式BOA的工作原理,提出了物联网系统中嵌入式Web服务器中的移植和应用方法.说明了BSP的移植和VxWorks映像文件制作方法.结合物联网中的具体应用,给出了一个多进程设计实例和云台控制器信息接收器的设计思路.

  18. Revision of the genus Cuvierina Boas, 1886 based on integrative taxonomic data, including the description of a new species from the Pacific Ocean (Gastropoda, Thecosomata).

    Science.gov (United States)

    Burridge, Alice K; Janssen, Arie W; Peijnenburg, Katja T C A

    2016-01-01

    Shelled pteropods (Gastropoda, Thecosomata, Euthecosomata) are a group of holoplanktonic gastropods that occur predominantly in the surface layers of the world's oceans. Accurate species identifications are essential for tracking changes in species assemblages of planktonic gastropods, because different species are expected to have different sensitivities to ocean changes. The genus Cuvierina has a worldwide warm water distribution pattern between ~36°N and ~39°S. Based on an integrative taxonomic approach combining morphometric, genetic, and biogeographic information, the two subgenera of Cuvierina , Cuvierina s. str. and Urceolarica , are rejected. A new species is introduced: Cuvierina tsudai sp. n. , which has to date been considered the same species as Cuvierina pacifica . Cuvierina tsudai sp. n. is endemic to the Pacific Ocean and is characterised by a shell height of 7.2-8.0 mm, a moderately cylindrical shell shape, the absence of micro-ornamentation and a triangular aperture. Cuvierina pacifica is restricted to the centre of the oligotrophic southern Pacific gyre, has a shell height of 6.6-8.5 mm, a more cylindrical shell shape, no micro-ornamentation and a less triangular aperture than Cuvierina tsudai sp. n.

  19. The Boa-based Remote Monitoring System on Embeded Linux Platform%嵌入式Linux下基于BOA的远程控制

    Institute of Scientific and Technical Information of China (English)

    高巍; 钟梅; 徐松惠

    2009-01-01

    分析了在嵌入式Linux平台下构建Web服务器的应用前景,介绍了利用嵌入式Web服务器实现Web远程监控系统的体系结构,给出了在ARM9处理器上利用开源Boa作为Web服务器的远程监控系统的设计及关键技术的实现,并以远程灯光控制为例介绍了这一解决方案的典型应用.

  20. Kitchen Information Monitor System Based on Boa Web Server%基于Boa服务器的厨房信息Web监控系统

    Institute of Scientific and Technical Information of China (English)

    叶丹

    2009-01-01

    设计了基于ARM的嵌入式技术和Boa服务器实现的家用厨房信息Web监控系统,该系统包括前端厨房环境信息采集、控制端、网络传输和远程监控四个部分,利用因特网动态Web技术实现远程对家庭厨房安全状态的监控.

  1. Investigation of Key Technology Based on the Embedded System of Boa%基于Boa的嵌入式Web服务器关键技术研究

    Institute of Scientific and Technical Information of China (English)

    宋扬; 马彪; 秦晓丽

    2007-01-01

    利用Boa构建了基于Arm-Linux操作系统的嵌入式Web服务器,并在此基础上深入研究了动态Web技术的实现,提出了交互式用户应用程序的设计方法,并给出了相应实现过程的实例.

  2. Performance of Single-Use FlexorVue vs Reusable BoaVision Ureteroscope for Visualization of Calices and Stone Extraction in an Artificial Kidney Model.

    Science.gov (United States)

    Schlager, Daniel; Hein, Simon; Obaid, Moaaz Abdulghani; Wilhelm, Konrad; Miernik, Arkadiusz; Schoenthaler, Martin

    2017-11-01

    To evaluate and compare Flexor ® Vue™, a semidisposable endoscopic deflection system with disposable ureteral sheath and reusable visualization source, and a nondisposable fiber optic ureteroscope in a standard in vitro setting. FlexorVue and a reusable fiber optic flexible ureteroscope were each tested in an artificial kidney model. The experimental setup included the visualization of colored pearls and the extraction of calculi with two different extraction devices (NCircle ® and NGage ® ). The procedures were performed by six experienced surgeons. Visualization time, access to calices, successful stone retraction, and time required were recorded. In addition, the surgeons' workload and subjective performance were determined according to the National Aeronautics and Space Administration-task load index (NASA-TLX). We referred to the Likert scale to assess maneuverability, handling, and image quality. Nearly all calices (99%) were correctly identified using the reusable scope, indicating full kidney access, whereas 74% of the calices were visualized using FlexorVue, of which 81% were correctly identified. Access to the lower poles of the kidney model was significantly less likely with the disposable device, and time to completion was significantly longer (755 s vs 153 s, p NASA-TLX scores were significantly higher using FlexorVue. The conventional reusable device also demonstrated superior maneuverability, handling, and image quality. FlexorVue offers a semidisposable deflecting endoscopic system allowing basic ureteroscopic and cystoscopic procedures. For its use as an addition or replacement for current reusable scopes, it requires substantial technical improvements.

  3. Producción masiva de Romanomermis iyengari (Nematoda: Mermithidae y su aplicación en criaderos de anofelinos en Boa Vista (Roraima, Brasil

    Directory of Open Access Journals (Sweden)

    Alberto Santamarina Mijares

    2000-03-01

    Full Text Available Para desarrollar la producción masiva del nemátodo Romanomermis iyengari Welch, se llevó a cabo el diseño y montaje de una bioplanta en las instalaciones de la Universidad Federal del Estado de Roraima, Brasil, tras un convenio con la Secretaría de Salud del mencionado estado. El objetivo de este trabajo fue establecer el proceso básico de cría masiva del parásito para su posterior aplicación en criaderos de anofelinos. Se obtuvieron 68 cultivos por cada ciclo de siete días, con un total de 272 cultivos por mes. Antes de los tratamientos de campo se realizaron pruebas de laboratorio en las que se comprobó la gran susceptibilidad de las larvas de anofelinos a la infestación por R. iyengari, con tasas de parasitismo de 71 a 98%. Para evaluar la capacidad parasitaria de R. iyengari en condiciones de campo, se seleccionaron 12 criaderos naturales de anofelinos, con áreas que oscilaron entre 50 y 450 m², en los que se observó la presencia de larvas de mosquitos de las especies Anopheles albitarsis Lynch-Arribálzaga y Anopheles rondoni Neiva-Pinto, con densidades de 34 a 66 larvas/m². Para la dispersión del biolarvicida en los 12 criaderos se utilizó una bomba costal manual de fabricación nacional a una presión de dos atmósferas y se aplicó una dosis de 2 000 preparásitos/m². Siete días después de los tratamientos se observó una marcada reducción (85 a 97% de las poblaciones de anofelinos. Los resultados obtenidos demostraron la posibilidad de utilizar R. iyengari para controlar las poblaciones larvarias de ambas especies de anofelinos.

  4. Producción masiva de Romanomermis iyengari (Nematoda: Mermithidae y su aplicación en criaderos de anofelinos en Boa Vista (Roraima, Brasil

    Directory of Open Access Journals (Sweden)

    Santamarina Mijares Alberto

    2000-01-01

    Full Text Available Para desarrollar la producción masiva del nemátodo Romanomermis iyengari Welch, se llevó a cabo el diseño y montaje de una bioplanta en las instalaciones de la Universidad Federal del Estado de Roraima, Brasil, tras un convenio con la Secretaría de Salud del mencionado estado. El objetivo de este trabajo fue establecer el proceso básico de cría masiva del parásito para su posterior aplicación en criaderos de anofelinos. Se obtuvieron 68 cultivos por cada ciclo de siete días, con un total de 272 cultivos por mes. Antes de los tratamientos de campo se realizaron pruebas de laboratorio en las que se comprobó la gran susceptibilidad de las larvas de anofelinos a la infestación por R. iyengari, con tasas de parasitismo de 71 a 98%. Para evaluar la capacidad parasitaria de R. iyengari en condiciones de campo, se seleccionaron 12 criaderos naturales de anofelinos, con áreas que oscilaron entre 50 y 450 m², en los que se observó la presencia de larvas de mosquitos de las especies Anopheles albitarsis Lynch-Arribálzaga y Anopheles rondoni Neiva-Pinto, con densidades de 34 a 66 larvas/m². Para la dispersión del biolarvicida en los 12 criaderos se utilizó una bomba costal manual de fabricación nacional a una presión de dos atmósferas y se aplicó una dosis de 2 000 preparásitos/m². Siete días después de los tratamientos se observó una marcada reducción (85 a 97% de las poblaciones de anofelinos. Los resultados obtenidos demostraron la posibilidad de utilizar R. iyengari para controlar las poblaciones larvarias de ambas especies de anofelinos.

  5. O ensino de literatura em Boa Vista-RR: "aprendizagem literária nas escolas de Ensino Médio"

    OpenAIRE

    Herica Maria Castro dos Santos

    2012-01-01

    Os diversos sistemas de avaliação nacionais como ENEM, SAEB, dentre outros, vêm demonstrando ao longo dos anos um quadro triste da educação brasileira, o fracasso dos estudantes do país em ler e interpretar os diversos tipos de textos. No que tange ao Ensino Médio, o quadro é ainda mais desesperador tamanha a deficiência que os estudantes apresentam ao se deparar com diversos estudos literários. Fica evidente que a grande parcela dos alunos não tem apreendido os conhecimentos necessários p...

  6. Política de mobilidade urbana sustentável: os impactos das ciclovias na qualidade de vida dos habitantes de Boa Vista, Brasil.

    OpenAIRE

    Matias, Eduardo Henrique do Vale

    2017-01-01

    Dissertação de Mestrado em Gestão e Políticas Públicas A qualidade de vida da população urbana é cada vez mais discutida no estudo das políticas públicas. Em um cenário de crescimento e concentração da população nos aglomerados urbanos, a vida do cidadão tem sido afetada por graves problemas, sobretudo, na questão do deslocamento urbano. A política de mobilidade urbana sustentável tem a finalidade de proporcionar o acesso amplo e democrático ao espaço urbano, de forma segura, socialmente i...

  7. Análise dos aspectos institucionais da regulação de OGMs no Brasil: boas práticas de governança ambiental?

    Directory of Open Access Journals (Sweden)

    Denise Gallo Pizella

    2012-06-01

    Full Text Available The release for the planting of Genetically Modified Organisms (GMOs is a controversial issue and requires care because it involves the country’s food security, the sovereignty of producers about seed use and the long-term potential environmental risks. Thus, it is important to analyze how the decision-making structures, both formal and informal, are established to address these issues, i.e. environmental governance of GMOs in Brazil, which is the purpose of this article. Among the good governance practices to be analyzed, we will be using the following parameters: popular participation in decision-making, and access to information and environmental justice. The following results were obtained: from the standpoint of public participation, there are flaws, as decision-makers have little social permeability, therefore CTNBio holds public hearings only by its own decision or by court order, which limits access to participation in the deliberation on GMOs. Regarding access to information, we also pointed out problems, as the Biosafety Information System has not been implemented. Environmental justice is inefficient since many cases of contamination of organic and conventional varieties by GMOs economically harm farmers, especially the first ones, who are at risk of losing their organic certification. Moreover, the decision on conducting environmental impact studies is determined by CTNBio, injuring principles that give this task to the organs of SISNAMA. We conclude therefore that the regulation of GMOs in Brazil does not have good environmental governance.

  8. A gestão eficaz dos resíduos no meio das boas práticas da indústria farmacêutica

    OpenAIRE

    Trecco, Cecilia; Castello, Vanesa; Romina, Kedikian; Sobrero, Cecilia; Sisti, Ada; Oviedo, Sergio

    2011-01-01

    Introduction. Pharmaceutical industries use raw materials,, energy,, capital and labor force to make sociably desirable goods but, also, produce undesirable sub products for which, usually, there are no positive pricing,, nor markets. Among those sub products there are pollution emissions, waste waters and dangerous/not dangerous waste material. The volume of sub products exceeds the biophysical capacities for their assimilation and handling, thus becoming a great challenge for industrial man...

  9. BOAS ADMINISTRAÇÕES ELEGEM CANDIDATOS? UMA ANÁLISE DO COMPORTAMENTO DOS ELEITORES EM SETE CAPITAIS BRASILEIRAS NAS ELEIÇÕES DE 2008

    Directory of Open Access Journals (Sweden)

    Adriano Oliveira

    2009-12-01

    Full Text Available Are well evaluated mayors reelected or elect their peers? This article aims at testing the following hypothesis considering the Brazilian 2008 elections, presented by Almeida (2008: is a good government reelected or elects its supporters? The article presents the results of seven Brazilian capitals in 2008. At first I verify if there is a relationship between a well evaluated mayor administration and election success. I consider good administration as the causal variable that explains the victory of the candidate. However, when we analyze the election results from the seven capitals, other variable come up to explain the victory of the candidates in the elections. This means that the variable good administration when considered alone is not enough to explain the success of a political candidate. Using qualitative and quantitative research and developing a detailed analysis of election in Recife in 2008, this article concludes that the good administration variable affects the electoral success of a candidate. And that other variables also matter to explain the electoral victory of the candidate.

  10. 13 CFR 124.503 - How does SBA accept a procurement for award through the 8(a) BD program?

    Science.gov (United States)

    2010-01-01

    ... under the 8(a) BD program. (g) Basic Ordering Agreements (BOAs). A Basic Ordering Agreement (BOA) is not a contract under the FAR. See 48 CFR 16.703(a). Each order to be issued under the BOA is an... BOA in addition to offering and accepting the BOA itself. (1) SBA will not accept for award on a sole...

  11. Permanent Genetic Resources added to Molecular Ecology Resources Database 1 April 2010 – 31 May 2010

    NARCIS (Netherlands)

    Andree, K.; Axtner, J.; Bagley, M.J.; Govers, F.; Jacobsen, E.; Mendes, O.; Lee, van der T.A.J.

    2010-01-01

    This article documents the addition of 396 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Anthocidaris crassispina, Aphis glycines, Argyrosomus regius, Astrocaryum sciophilum, Dasypus novemcinctus, Delomys sublineatus,

  12. Postembryonic Nephrogenesis and Persistence of Six2-Expressing Nephron Progenitor Cells in the Reptilian Kidney.

    Directory of Open Access Journals (Sweden)

    Troy Camarata

    Full Text Available New nephron formation (nephrogenesis ceases in mammals around birth and is completely absent in adults. In contrast, postembryonic nephrogenesis is well documented in the mesonephric kidneys of fishes and amphibians. The transient mesonephros in reptiles (including birds and mammals is replaced by the metanephros during embryogenesis. Thus, one may speculate that postembryonic nephrogenesis is restricted to the mesonephric kidney. Previous reports have suggested the metanephros of non-avian reptiles (hereafter reptiles may continually form nephrons throughout life. We investigated the presence of adult nephrogenesis in reptiles by examining adult kidneys from several species including Trachemys scripta, Chrysemys picta, Boa constrictor, Tupinambis tegu, Anolis carolinensis, and Alligator mississipiensis among others. We found that all major reptilian groups (Testudines, Crocodylia, and Squamates showed the presence of adult nephrogenesis. The total amount of nephrogenesis varied greatly between species with turtles displaying the highest density of nephrogenesis. In contrast, we were unable to detect adult nephrogenesis in monotremes, and in the iguanid A. carolinensis. Nephron progenitor cells express the transcription factor Six2, which in mammals, becomes downregulated as the progenitor cell population is exhausted and nephrogenesis ends. Using the alligator as a model, we were able to detect Six2-positive cap mesenchyme cells in the adult kidney, which spatially correlated with areas of nephrogenesis. These results suggest that the metanephric kidney of reptiles has maintained the ability to continually grow new nephrons during postembryonic life, a process lost early in mammalian evolution, likely due to the persistence of a Six2-expressing progenitor cell population.

  13. Stable isotope tracer reveals that viviparous snakes transport amino acids to offspring during gestation.

    Science.gov (United States)

    Van Dyke, James U; Beaupre, Steven J

    2012-03-01

    Viviparity and placentation have evolved from oviparity over 100 times in squamate reptiles (lizards and snakes). The independent origins of placentation have resulted in a variety of placental morphologies in different taxa, ranging from simple apposition of fetal and maternal tissues to endotheliochorial implantation that is homoplasious with mammalian placentation. Because the eggs of oviparous squamates transport gases and water from the environment and calcium from the eggshell, the placentae of viviparous squamates are thought to have initially evolved to accomplish these functions from within the maternal oviduct. Species with complex placentae have also been shown to rely substantially, or even primarily, on placental transport of organic nutrients for embryonic nutrition. However, it is unclear whether species with only simple placentae are also capable of transporting organic nutrients to offspring. Among viviparous squamates, all of the snakes that have been studied thus far have been shown to have simple placentae. However, most studies of snake placentation are limited to a single lineage, the North American Natricinae. We tested the abilities of four species of viviparous snakes - Agkistrodon contortrix (Viperidae), Boa constrictor (Boidae), Nerodia sipedon (Colubridae: Natricinae) and Thamnophis sirtalis (Colubridae: Natricinae) - to transport diet-derived amino acids to offspring during gestation. We fed [(15)N]leucine to pregnant snakes, and compared offspring (15)N content with that of unlabeled controls. Labeled females allocated significantly more (15)N to offspring than did controls, but (15)N allocation did not differ among species. Our results indicate that viviparous snakes are capable of transporting diet-derived amino acids to their offspring during gestation, possibly via placentation.

  14. Rut wat Boas se �voete� oopgemaak en by hom gaan l� het: Die betekenis van hierdie simboliese aksie in Rut 3:7 in die lig van Eksodus 4:25

    Directory of Open Access Journals (Sweden)

    Philip Venter

    2013-02-01

    Full Text Available Ruth who uncovered Boaz's 'feet' and had laid there with him: The significance of this symbolic act in Ruth 3:7 in the light of Exodus 4:25. This article investigates the possibility that Ruth 3:7, where Ruth went to lie at Boaz� �feet�, can be read in an intertextual way in the context of Exodus 4:25. In Exodus 4:24�26, whilst at a camping place on their way to Egypt, the Lord came to kill Moses. Then Zipporah, his wife, took a sharp stone (or stone knife, cut off the foreskin of her son and touched Moses� �feet� with it. Because of the circumcision she said to Moses: �You are a bridegroom of blood to me�. And so the Lord spared the life of Moses. Zipporah took the initiative and because of this, God�s will and plan for Moses could still be reached. The covenant duty of circumcision, according to Genesis 17:10�14, could also be accomplished through her intervention. This section also clearly illustrates that God welcomes non-Israelites to enter into the community of Israel. In Ruth 3:7, the same word for feet is used as in Exodus 4:25, namely . The analogous use of this word clearly emphasises the importance of the functioning of the covenant of God with Israel. There are also other similarities between these verses of Scripture. It is indicated that Ruth, like Zipporah, also took the initiative and intervened to ensure that God�s covenant plan for Israel will be accomplished. It is also indicated that Ruth, like Zipporah, is accepted into the community of Israel and that she will play an important role ensuring the future of the offspring of Mahlon/Boaz.

  15. A survey on some biochemical and pharmacological activities of venom from two Colombian colubrid snakes, Erythrolamprus bizona (Double-banded coral snake mimic) and Pseudoboa neuwiedii (Neuwied's false boa).

    Science.gov (United States)

    Torres-Bonilla, Kristian A; Floriano, Rafael S; Schezaro-Ramos, Raphael; Rodrigues-Simioni, Léa; da Cruz-Höfling, Maria Alice

    2017-06-01

    Colombian colubrid snake venoms have been poorly studied. They represent a great resource of biological, ecological, toxinological and pharmacological research. We assessed some enzymatic properties and neuromuscular effects of Erythrolamprus bizona and Pseudoboa neuwiedii venoms from Colombia. Proteolytic, amidolytic and phospholipase A 2 (PLA 2 ) activities were analyzed using colorimetric assays and the neuromuscular activity was analyzed in chick biventer cervicis (BC) preparations. The venom of both species showed very low PLA 2 and amidolytic activities; however, both exhibited high proteolytic activity, which in E. bizona venom surpassed that of P. neuwiedii venom. E. bizona and P. neuwiedii venoms provoked partial neuromuscular blockade, which was more prominent in P. neuwiedii venom. E. bizona venom (30 μg/ml) induced a significant potentiation of the contracture response to exogenous ACh (110 μM), which was not accompanied by twitch height alteration, whereas the highest venom concentration (100 μg/ml) inhibited contracture responses to both ACh and KCl (40 mM). In contrast, P. neuwiedii venom (30 and 100 μg/ml) caused significant reduction in the contracture responses to exogenous ACh and KCl. The morphological analyses showed high myotoxic effects in the muscle fibers of BC incubated with either venoms; however, they are more prominent in the P. neuwiedii venom. Our results suggest that the myotoxicity of the venom of the two Colombian species can be ascribed to their high proteolytic activity. An interesting data was the potentiation of the ACh-induced contracture, but not the twitch height, caused by E. bizona venom, at a concentration that is harmless to muscle fibers integrity. This phenomenon remains to be further elucidated, and suggest that a possible involvement of post-synaptic receptors cannot be discarded. This work is a contribution to expand the knowledge on colubrid venoms; it allows envisaging that the two venoms offer the potential to go further in the identification of their components and biological targets. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Boas práticas em gestão ambiental de Instituições de Ensino Superior: o caso da Universidade de Turku de Ciências Aplicadas

    Directory of Open Access Journals (Sweden)

    Elis Marina Tonet Motta

    2017-08-01

    Full Text Available A indicação de que parte do atual cenário ambiental é resultante das atividades humanas tem gerado um aumento da pressão política e social sobre as organizações, para que essas adotem práticas ambientais eficazes. Essa pressão atualmente atinge aos mais diversos setores, inclusive o educacional. Dessa forma, a incorporação das questões ambientais ao planejamento estratégico, denominada estratégia ambiental, demonstra ser uma oportunidade de gerenciar, de forma eficaz, as diversas pressões e desafios da atualidade. As Instituições de Ensino Superior, em especial, possuem uma grande responsabilidade de executar aquilo que ensinam. Assim, o presente artigo tem por objetivo avaliar a gestão ambiental e a incorporação dos temas ambientais ao planejamento estratégico de uma Instituição de Ensino Superior internacional, por meio da percepção de seus colaboradores. Os resultados demonstram que a estratégia ambiental adotada pela Instituição possui natureza reativa, contrariando em partes sua responsabilidade de instituição promotora do conhecimento. Verifica-se, igualmente, que a Instituição possui um sistema de gestão ambiental informal, composto por diversas ações que possuem exigência legal. Identifica-se, por fim, inúmeras possibilidades de melhoria dos processos de gestão ambiental da organização.

  17. Procedures development and methodology of control for application of good manufacture practices (GMP) on human blood irradiation; Desenvolvimento de procedimentos e metodologia de controle para aplicacao de boas praticas de fabricacao (BPF) na irradiacao de sangue humano

    Energy Technology Data Exchange (ETDEWEB)

    Boghi, Claudio

    2008-07-01

    The irradiation of human blood is used to avoid the TA-GVHD (transfusion-associated graft-versus-host-disease), a rare but devastating adverse effect of leukocytes present in blood components for a immunocompetent transfusion recipients. Usually this irradiation practice is performed to a physical elimination of leukocytes. The implementation of the procedures will assure that the properly dose in a range of 25 Gy to 50 Gy will be delivered to the blood in the bag collected in a blood tissue bank. The studies of the procedures in order to establish a GMP (Good Manufacturing Practices) were developed under the guidelines of the standard ISO 11137 - Sterilization of health care products - Requirements for validation and routine control - Radiation sterilization. In this work, two dosimetric systems were used for dose mapping during the studies of irradiator qualification, loading pattern, irradiation process validation and auditing. The CaS0{sub 4}:Dy dosimeter presented difficulties concerning to uncertainty on dose measurement, stability, traceability and calibration. The PMMA and Gafchromic dosimetric systems have shown a better performance and were adopted on studies of irradiators qualification that are necessary to implementation of GMP. The irradiation tests have been done in a Gammacell 220 irradiator. The developed procedures can be adapted for different kinds of gamma irradiators, allowing implanting a quality assurance program and a GMP for blood irradiation. (author)

  18. A conformação simbólica sobre um atrativo turístico: o caso da Charqueada Boa Vista em Pelotas RS, através dos comentários no site TripAdvisor

    Directory of Open Access Journals (Sweden)

    Caroline Dutra Bilhalva

    2018-02-01

    Full Text Available O trabalho apresenta uma reflexão sobre a conformação simbólica de um atrativo turístico. Esse fenômeno será compreendido com base no teórico Ernst Cassirer, o qual parte da premissa que os seres humanos são livres no plano de suas significações de mundo, noção que justifica as diferentes qualificações para o mesmo atrativo turístico. Tendo em conta que os empreendedores do setor turístico objetivam uma forma de abarcar a demanda como um todo. Entende-se que o trabalho é relevante, pois pontua diferentes posições. Com os perfis compreendidos é mais fácil criar e propor medidas que envolva números significativos de turistas. Analisar comentários no site TripAdvisor pode ser considerado um modo sensorizar e monitorar o turista. Essa medida levanta dados importantes para a gestão, podendo estabelecer maneiras mais efetivas de corrigir possível falhas. O caso abordado nesse estudo é destaque pelo trabalho de marketing realizado, através deste mecanismo conseguiu-se reverter a conformação simbólica negativa que se tinha sobre o espaço para a condição de área requintada e ambiente atrativo destinado ao nicho de mercado do turismo matrimonial e de negócios.

  19. Construção para o desenvolvimento: sobre a elaboração do manual de boas práticas de construção para Díli, Timor-Leste

    OpenAIRE

    Moita, Maria Valladares Pacheco

    2009-01-01

    Mestrado em Desenvolvimento, Diversidades Locais e Desafios Mundiais: Análise e Gestão A presente dissertação descreve a reflexão e a análise realizadas em torno de um projecto profissional levado a cabo entre Abril e Outubro de 2009, na OIM (Organização Internacional para as Migrações) em Timor-Leste, com o objectivo de melhorar as práticas de construção em Díli. Depois dos efeitos devastadores da crise política de 2006 e dos conflitos que se seguiram, maisde 100,000 pessoa...

  20. Identificando os desafios e as boas práticas para o transporte urbano de cargas, por meio de uma revisão bibliográfica sistemática

    Directory of Open Access Journals (Sweden)

    Cintia Machado Oliveira

    2016-12-01

    Full Text Available This purpose of this paper is to identify, through a systematic literature review, the challenges faced in urban freight transportation and best practices that could be implemented in the field, considering social and environmental aspects. The research also identifies the actors (in public and private sectors which could be responsible for implementing such practices. Moreover, the paper proposes a procedure for conducting systematic literature reviews, established exclusively for this study. The conclusions identify 26 best practices capable of supporting the solution of 16 challenges. Results indicate that 31% of these challenges could be solved by public actors, 44% by the private sector and 25% of them by both agents, working, respectively, in 27%, 65% and 8% of the practices. Besides, it was identified that 81% of the best practices can contribute positively, considering economic aspects. The research was limited to scientific papers. Therefore, it is recom-mended that future studies consider a field survey to confirm that the challenges and good practices identified are part of the reality of cities.

  1. Dermatose por IgA e IgG linear: relato de caso com boa resposta terapêutica à dapsona e ao micofenolato mofetil Linear IgA/IgG bullous dermatosis: successful treatment with dapsone and mycophenolate mofetil

    Directory of Open Access Journals (Sweden)

    Leny Passos

    2011-08-01

    Full Text Available Relata-se o caso de paciente feminina, de 21 anos, com dermatose por IgA e IgG linear. Inicialmente, a resposta clínica foi favorável à dapsona. Após a interrupção desta medicação, por crise de anemia sintomática, precipitada por malária, houve piora da doença, apesar da utilização da prednisona e pulsoterapia com metilprednisolona. A reintrodução da dapsona, associada ao micofenolato mofetil, possibilitou o controle da enfermidadeA 21-year-old female presenting linear IgA and IgG disease initially responded well to dapsone therapy. However, the treatment with dapsone was withdrawn due to severe anemia induced by malaria, which led to worsening of the clinical picture. Although prednisone and methylprednisolone were tried, the patient responded only to the association of dapsone and mycophenolate mofetil

  2. Cinema documentário, política de boa vizinhança e a construção de uma imagem do Brasil na década de 1940

    Directory of Open Access Journals (Sweden)

    Priscila Faulhaber Barbosa

    Full Text Available O artigo analisa a construção de uma imagem do Brasil pelos norte-americanos. Partimos do exame de documentos do Conselho de Fiscalização das Expedições Científicas e Artísticas Nacionais, procurando identificar a significação da preocupação com a construção de tal imagem por parte de agências e representantes governamentais, correlacionando-a com a problemática dos objetos fronteiriços por meio do exame dos dispositivos de governo que envolveram relações entre organismos do Brasil e dos Estados Unidos. Esse pano de fundo é uma abordagem que desemboca no exame de um conjunto de filmes produzidos com o apoio do Escritório de Assuntos Interamericanos, chefiado por Nelson Rockefeller, e do governo brasileiro, durante a década de 1940. Consideramos esses filmes como objetos fronteiriços, representando distintas perspectivas do país desenvolvido, interessado na exuberância natural e no potencial político e econômico de um país continental que começou a forjar-se enquanto nação em pleno desenvolvimento, com instituições voltadas ao patrimônio. Nesse contexto, o cinema documentário representou muito mais do que o retrato de um excêntrico país do Terceiro Mundo. Ele representou uma complexa estratégia política entre ambos os países, em prol do progresso regido pelos novos rumos da integração de mercados em moldes americanos.

  3. O Brasil está envelhecendo: boas e más notícias por uma perspectiva epidemiológica Brazil is aging: good and bad news from an epidemiological perspective

    Directory of Open Access Journals (Sweden)

    Regiane Garrido

    2002-04-01

    Full Text Available O envelhecimento mundial é um fenômeno que tem sido muito discutido na última década. O rápido processo de envelhecimento observado nos países em desenvolvimento, como o Brasil, ainda não tem sido suficientemente estudado para fornecer os elementos necessários ao desenvolvimento de políticas adequadas para essa parcela da população. O objetivo deste artigo é atualizar os leitores sobre o atual perfil do idoso no Brasil, dando destaque aos problemas de esfera da saúde mental. Além disto, pretende, pelos dados apresentados, discutir como os profissionais envolvidos no atendimento do paciente idoso podem ampliar e melhorar sua atuação.The world's population is under an aging process, and this demographic revolution is now affecting developing countries such as Brazil. The dramatic increase in the number of older adults observed in the last few years has had significant implications in health planning and delivery of health services, including mental health. This study reviews the current demographic profile of elderly population and its consequences for the practice of psychiatry and organization of mental health services in Brazil.

  4. Literatura infantil: espaço lúdico na Unidade Básica de Saúde do Bairro Boa Esperança em Sinop no Estado de Mato Grosso

    Directory of Open Access Journals (Sweden)

    Osmilda Pereira da Silva Albuquerque

    2014-03-01

    Full Text Available Este artigo aborda a utilização da literatura infantil na Unidade Básica de Saúde. Teve como objetivo identificar o conhecimento de profissionais da saúde sobre essa temática, possibilitando desenvolver práticas que integram educação e saúde, através da literatura infantil. O método utilizado foi o participativo com abordagem qualitativa, coletados através de entrevistas gravadas e transcritas. Os dados demonstraram que os profissionais da saúde, não têm conhecimento da temática abordada, mais são favoráveis a criação de um espaço lúdico pedagógico, para que incentive as crianças a leitura. Palavras-chave: ludicidade; saúde e educação; pedagogia.

  5. Anúncios de medicamentos em revistas médicas: ajudando a promover a boa prescrição? Drug advertisements in medical journals: promoting good prescription?

    Directory of Open Access Journals (Sweden)

    José Augusto Cabral de Barros

    2002-01-01

    Full Text Available Ante a inexistência de estudos no Brasil, este trabalho se propôs a fazer uma avaliação dos anúncios com base nos critérios sugeridos pela OMS e que deveriam incluir-se em qualquer material de divulgação. Foram avaliados todos os anúncios contidos nas edições de agosto/2000 a fevereiro/2001 do Jornal de Pediatria, Revista Brasileira de Medicina e Jornal Brasileiro de Medicina, averiguando a presença nos mesmos de: nome genérico, mecanismos de ação, efeito farmacológico, indicação, contra-indicação, posologia, reações adversas, interações, superdosagem, apresentação e fabricante/importador. Em um total de 1.774 páginas, 539 (30,4% se destinavam a anúncios, compreendendo 649 ao todo. Nenhum dos critérios propostos pela OMS esteve presente em todas as propagandas, e apenas em cerca de 20% delas há referência a reações adversas, contra-indicações e interações. Os produtos mais anunciados foram antibióticos, hipotensores e os à base da associação de vários fármacos. Omitindo dados importantes, em especial contra-indicações, reações adversas e interações, os anúncios são tendenciosos, atendendo a propósitos mercadológicos, não sendo um meio que subsidie a prescrição e a utilização correta e segura dos produtos anunciados.Supply and demand of drugs are influenced by different ways. Manufacturers' promotional strategies are outstanding a particular role being ascribed to advertising (ads in medical journals. Considering that studies on this issue are not available in Brazil a research was performed aimed at evaluating ads using as parameters WHO criteria for drug information that should be included in any informative material. All advertisements published in Jornal de Pediatria, Revista Brasileira de Medicina and Jornal Brasileiro de Medicina issues from August/2000 up to February/2001 were evaluated verifying the presence of generic name, mechanism of action, pharmacologic effects, indications, contraindications, dosing information, adverse effects, drugs interactions, overdose, types of formulation marketed, manufacturer and/or importer. In the total of 1.774 pages, 539 were occupied by 649 ads. No one of referred criteria was found in all ads and only 20% include contraindications, adverse effects and drugs interactions. The most advertised drugs were antibiotics, antihipertensives and combination products. Instead of subsidize prescription and adequate drug utilization ads are clearly biased obeying to marketing goals since meaningful data are missing.

  6. Acessibilidade do paciente à clinica de especialidades de endodontia: estudo dirigido dos inscritos aguardando em fila de espera, nos distritos de saúde Boa Vista e Cajuru do Município de Curitiba-PR

    OpenAIRE

    Wellington Menyrval Zaitter

    2009-01-01

    Inquéritos nacionais de saúde bucal indicam que uma parcela da população brasileira nunca passou por uma consulta com o cirurgião-dentista. Os motivos são variados, desde a falta de percepção desta necessidade até mesmo a dificuldade de acesso aos serviços de saúde. No Brasil o atendimento odontológico predominante é através do Sistema Único de Saúde que tem nas unidades básicas de saúde a porta de entrada a diversos serviços. Através da consulta odontológica o paciente é referendado a especi...

  7. Avaliação ultrassonográfica do aparelho reprodutor em serpentes vivíparas da família Boidae

    Directory of Open Access Journals (Sweden)

    Viviane C. Garcia

    2015-03-01

    Full Text Available A reprodução faz parte do ciclo de vida dos animais permitindo a perpetuação e a conservação das espécies. Em serpentes, existe uma escassez de informações técnicas a respeito do ciclo reprodutivo. Este estudo teve o objetivo de avaliar o aparelho reprodutivo por meio da ultrassonografia em serpentes vivíparas cativas da família Boidae, permitindo diagnosticar as diferentes fases reprodutivas. Foram avaliadas ultrassonograficamente onze serpentes adultas de quatro espécies da família Boidae: Eunectes murinus, Boa constrictor constrictor, Corallus hortulanus e Epicrates cenchria pertencentes ao acervo do Museu Biológico do Instituto Butantan, São Paulo Brasil. Para a avaliação ultrassonográfica, as serpentes foram contidas fisicamente com gancho herpetológico e depois manualmente por aproximadamente 15 minutos. A avaliação foi feita aplicando-se gel acústico sobre a pele e posicionando o transdutor na linha lateral-ventral direita e esquerda, em região medial do corpo em sentido crânio-caudal. O exame ultrassonográfico permitiu avaliar todo o ciclo reprodutivo nas serpentes. Nas avaliações ultrassonográficas das fêmeas pode-se definir as fases de desenvolvimento ovariano e ovidutal. Os folículos ovarianos durante a fase pré-vitelogênica foram visualizados como homogêneos e anecogênicos, em forma de "cacho de uva". Já na fase vitelogênica, os folículos estavam maiores e mais ecogênicos seguidos uns dos outros, como um "colar de pérolas". Quando não houve cópula, os folículos foram reabsorvidos dentro do ovário retornando a fase pré-vitelogênica. Na fase pós ovulatória foram visualizados três estágios bem definidos de desenvolvimento fetal dentro do oviduto: 1 logo após a ovulação (e fecundação, somente o vitelo foi visualizado; 2 o vitelo ocupava 60% e o feto 40% do ovo e 3 o feto estava formado e não havia vitelo. Nos machos, os testículos foram visualizados como uma imagem homogênea e

  8. Anti-inflammatory activity of animal oils from the Peruvian Amazon.

    Science.gov (United States)

    Schmeda-Hirschmann, Guillermo; Delporte, Carla; Valenzuela-Barra, Gabriela; Silva, Ximena; Vargas-Arana, Gabriel; Lima, Beatriz; Feresin, Gabriela E

    2014-10-28

    Animal oils and fats from the fishes Electrophorus electricus and Potamotrygon motoro, the reptiles Boa constrictor, Chelonoidis denticulata (Geochelone denticulata) and Melanosuchus niger and the riverine dolphin Inia geoffrensis are used as anti-inflammatory agents in the Peruvian Amazon. The aim of the study was to assess the topic anti-inflammatory effect of the oils/fats as well as to evaluate its antimicrobial activity and fatty acid composition. The oils/fats were purchased from a traditional store at the Iquitos market of Belen, Peru. The topic anti-inflammatory effect was evaluated by the mice ear edema induced by arachidonic acid (AA) and 12-O-tetradecanoylphorbol-13-acetate (TPA) at the dose of 3mg oil/ear. Indomethacine and nimesulide were used as reference anti-inflammatory drugs. The application resembles the traditional topical use of the oils. The antimicrobial effect of the oils/fats was assessed by the microdilution test against reference strains of Escherichia coli, Staphylococcus aureus and Salmonella enteritidis. The fatty acid composition of the oils/fats (as methyl esters) was determined by GC and GC-MS analysis after saponification. All oils/fats showed topic anti-inflammatory activity, with better effect in the TPA-induced mice ear edema assay. The most active drugs were Potamotrygon motoro, Melanosuchus niger and Geochelone denticulata. In the AA-induced assay, the best activity was found for Potamotrygon motoro and Electrophorus electricus oil. The oil of Electrophorus electricus also showed a weak antimicrobial effect with MIC values of 250 µg/mL against Escherichia coli ATCC 25922 and Salmonella enteritidis-MI. The main fatty acids in the oils were oleic, palmitic and linoleic acids. Topical application of all the oils/fats investigated showed anti-inflammatory activity in the mice ear edema assay. The effect can be related with the identity and composition of the fatty acids in the samples. This study gives support to the traditional

  9. Promoting Cultural Tourism Industry in Africa: The Place of African ...

    African Journals Online (AJOL)

    Mrs Afam

    Key words: Study, African Indigenous Religion, Cultural, Main Stay, Tourism, ... wildlife – and recreational aspects such as festivals, songs, dances, folktales and ..... constrictor to entertain the crowd by dancing to a piece of high-life music.

  10. Garrison Dam/Lake Sakakawea Master Plan with Integrated Programmatic Environmental Assessment, Missouri River, Montana: Update of Design Memorandum MGR-107D

    Science.gov (United States)

    2007-12-14

    Toxicodendron radicans), wild strawberry ( Fragaria virginiana), violets (Oxalis violacea), and wild parsley (Lomatium orientale) fill in the...prairie rattlesnakes (Crotalus viridis ), yellowbelly racers (Coluber constrictor), western hognose snake (Heterdon nasicus), and smooth green snakes

  11. Radiation dose to dysphagia aspiration-related structures and its effect on swallowing: Comparison of three-dimensional conformal radiotherapy and intensity-modulated radiation therapy plans

    Directory of Open Access Journals (Sweden)

    Chelakkot G Prameela

    2016-01-01

    Conclusion: Our study is probably one of the few studies predicting possible mean dose constraints for superior constrictor, the base of the tongue and larynx. Further prospective studies are required to confirm these and to improve the swallowing quality.

  12. Revision of Boletus section Appendiculati (Boletaceae) in Bulgaria with a key to the Balkan species

    OpenAIRE

    ASSYOV, Boris

    2012-01-01

    The paper presents the results from the taxonomic revision of Boletus section Appendiculati in Bulgaria. Descriptions are provided based on Bulgarian specimens for the 5 species of the section: Boletus appendiculatus, B. fechtneri, B. fuscoroseus, B. regius, and B. subappendiculatus. The priority of the name B. fuscoroseus against B. pseudoregius is briefly discussed. A dichotomous key for the determination of members is also included.

  13. Satiety and eating patterns in two species of constricting snakes

    DEFF Research Database (Denmark)

    Nielsen, Torben P; Jacobsen, Magnus W.; Wang, Tobias

    2011-01-01

    Satiety has been studied extensively in mammals, birds and fish but very little information exists on reptiles. Here we investigate time-dependent satiation in two species of constricting snakes, ball pythons (Python regius) and yellow anacondas (Eunectes notaeus). Satiation was shown to depend...

  14. Author Details

    African Journals Online (AJOL)

    Odeniran, P.O.. Vol 30, No 2 (2015) - Articles Evaluating the effectiveness of varying concentrations of permethrin on ticks of genus Aponoma on Royal Pythons (Python Regius) Abstract. ISSN: 0856-1451. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

  15. Browse Title Index

    African Journals Online (AJOL)

    Items 351 - 399 of 399 ... ... of pentastomiasis in the royal python (Python regius), Abstract PDF. AB Ayinmode, AO Adedokun, A Aina, V Taiwo. Vol 48, No 3 (2014), Therapeutic effect of continuous exercise training program on serum creatinine concentration in men with hypertension: A randomized controlled trial, Abstract PDF.

  16. Browse Title Index

    African Journals Online (AJOL)

    Vol 16, No 2 (2012), Identification par coprologie des helminthes de python regius dans le département du zou au Bénin, Afrique de l'Ouest, Abstract. MN Assogba, IYA Karim, IT Akoiret, F Fagbohoun, EN Zannou. Vol 9, No 2 (2007), IGNAME, PLANTE ALIMENTAIRE COMMERCIALE ET CULTURELLE AU NORD BENIN ...

  17. Tanzania Veterinary Journal - Vol 30, No 2 (2015)

    African Journals Online (AJOL)

    Evaluating the effectiveness of varying concentrations of permethrin on ticks of genus Aponoma on Royal Pythons (Python Regius) · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. H.O. Jegede, P.O. Odeniran, S.F. Ambali, 13-18 ...

  18. Browse Title Index

    African Journals Online (AJOL)

    Items 1 - 50 of 127 ... Vol 30, No 2 (2015), Evaluating the effectiveness of varying concentrations of permethrin on ticks of genus Aponoma on Royal Pythons (Python Regius), Abstract. H.O. Jegede, P.O. Odeniran, S.F. Ambali. Vol 30, No 1 (2015), Evaluation of Bovine trypanosomosis intervention in Chunya District, Tanzania ...

  19. Browse Title Index

    African Journals Online (AJOL)

    Items 101 - 150 of 199 ... Vol 35, No 2 (2017), Infectious bursal disease outbreak in 19-week old commercial pullets in Ibadan, Nigeria: a case report, Abstract. Oluwaseun O. Esan, John Ogunsola. Vol 21, No 1 (2003), Infestation of Royal Python (Python regius) with ticks Amblyomma hebraeum in Ibadan Zoo, Nigeria, Abstract.

  20. Author Details

    African Journals Online (AJOL)

    Adedokun, O.A.. Vol 21, No 1 (2003) - Articles Infestation of Royal Python (Python regius) with ticks Amblyomma hebraeum in Ibadan Zoo, Nigeria Abstract. ISSN: 0794-4845. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

  1. Gastrointestinal helminths of resident wildlife at the Federal ...

    African Journals Online (AJOL)

    In terms of feeding category, carnivorous species namely the (Aquila spilogaster) and Royal python (P. regius) have the highest species richness count of parasites. Non-nematode helminths detected include protozoons (Isospora and Eimeria) and Cestodes segments suspected to be Echinococcus proglotids. Knowledge ...

  2. On the Advantages and Defects of the American Structuralism

    Institute of Scientific and Technical Information of China (English)

    徐晓莹

    2004-01-01

    During the years at the end of the nineteenth century and beginning of the twentieth century when Saussure was working out his ideas in Europe, synchronic linguistics was emerging independently, and in a very different style, in America, under the leadership of the anthropologist Franz Boas. Boas set a direction for American linguistics. The school founded by Boas was called structural linguistics. Beside Boas, the other two major representatives of this school during this period were: Sapir and Bloomfield.

  3. Characterisation of Brachycephalic Obstructive Airway Syndrome in French Bulldogs Using Whole-Body Barometric Plethysmography

    Science.gov (United States)

    Liu, Nai-Chieh; Sargan, David R.; Adams, Vicki J.; Ladlow, Jane F.

    2015-01-01

    Brachycephalic obstructive airway syndrome (BOAS) is an important health and welfare problem in several popular dog breeds. Whole-body barometric plethysmography (WBBP) is a non-invasive method that allows safe and repeated quantitative measurements of respiratory cycles on unsedated dogs. Here respiratory flow traces in French bulldogs from the pet population were characterised using WBBP, and a computational application was developed to recognise affected animals. Eighty-nine French bulldogs and twenty non-brachycephalic controls underwent WBBP testing. A respiratory functional grading system was used on each dog based on respiratory signs (i.e. respiratory noise, effort, etc.) before and after exercise. For development of an objective BOAS classifier, functional Grades 0 and I were considered to have insignificant clinical signs (termed here BOAS-) and Grades II and III to have significant signs (termed here BOAS+). A comparison between owner-perception of BOAS and functional grading revealed that 60 % of owners failed to recognise BOAS in dogs that graded BOAS+ in this study.WBBP flow traces were found to be significantly different between non-brachycephalic controls and Grade 0 French bulldogs; BOAS- and BOAS+ French bulldogs. A classifier was developed using quadratic discriminant analysis of the respiratory parameters to distinguish BOAS- and BOAS + French bulldogs, and a BOAS Index was calculated for each dog. A cut-off value of the BOAS Index was selected based on a receiver operating characteristic (ROC) curve. Sensitivity, specificity, positive predictive value, and negative predictive value of the classifier on the training group (n=69) were 0.97, 0.93, 0.95, and 0.97, respectively. The classifier was validated using a test group of French bulldogs (n=20) with an accuracy of 0.95. WBBP offers objective screening for the diagnosis of BOAS in French Bulldogs. The technique may be applied to other brachycephalic breeds affected by BOAS, and possibly to

  4. A Novel Evolutionary Algorithm Inspired by Beans Dispersal

    Directory of Open Access Journals (Sweden)

    Xiaoming Zhang

    2013-02-01

    Full Text Available Inspired by the transmission of beans in nature, a novel evolutionary algorithm-Bean Optimization Algorithm (BOA is proposed in this paper. BOA is mainly based on the normal distribution which is an important continuous probability distribution of quantitative phenomena. Through simulating the self-adaptive phenomena of plant, BOA is designed for solving continuous optimization problems. We also analyze the global convergence of BOA by using the Solis and Wetsarsquo; research results. The conclusion is that BOA can converge to the global optimization solution with probability one. In order to validate its effectiveness, BOA is tested against benchmark functions. And its performance is also compared with that of particle swarm optimization (PSO algorithm. The experimental results show that BOA has competitive performance to PSO in terms of accuracy and convergence speed on the explored tests and stands out as a promising alternative to existing optimization methods for engineering designs or applications.

  5. Infecção por Bordetella pertussis com hipertensão pulmonar grave num recém-nascido com boa evolução clínica – Caso clínico

    Directory of Open Access Journals (Sweden)

    Sérgia Soares

    2008-09-01

    Full Text Available Resumo: Apesar da ampla cobertura vacinal, a infecção por Bordetella pertussis está longe de estar controlada. Os recém-nascidos e lactentes ainda sem imunização completa e filhos de mães com baixos títulos de anticorpos para a Bordetella pertussis são altamente susceptíveis à infecção e têm maior risco de doença grave e morte. A infecção por Bordetella pertussis associada a hipertensão pulmonar no recém-nascido é frequentemente fatal. Os autores descrevem um caso clínico de doença grave num recém-nascido com insuficiência respiratória aguda e hipertensão pulmonar grave, tratado com sucesso com sildenafil e óxido nítrico inalado.Rev Port Pneumol 2008; XIV (5: 687-692 Abstract: In spite of the availability and widespread use of vaccines, pertussis is far from controlled. Newborns and infants too young to be fully vaccinated, born from mothers with low antibody titers to Bordetella pertussis, are highly susceptible to infection and at risk of severe disease and death. Pertussis associated with pulmonary hypertension in the newborn is often fatal. The authors report a clinical case of severe pertussis-induced respiratory failure associated to severe pulmonary hypertension in a neonate successfully treated with sildenafil and inhaled nitric oxide.Rev Port Pneumol 2008; XIV (5: 687-692 Palavras-chave: Recém-nascido, oxido nítrico, pertussis, hipertensão pulmonar, sildenafil, Key-words: Neonate, nitric oxide, pertussis, pulmonary hypertension, sildenafil

  6. Por trás de uma tampinha de Coca-Cola um mundo de coisas boas!: propaganda no Brasil (1950-1960 = Behind a cover of Coca-Cola a world of good things!: propaganda in Brazil (1950-1960

    Directory of Open Access Journals (Sweden)

    Bammann, Kellen

    2014-01-01

    Full Text Available O artigo tem como fonte de pesquisa os anúncios de Coca-Cola veiculados nas revistas brasileiras O Cruzeiro e Manchete entre 1950 e 1960. O ensaio procura demonstrar de que forma as campanhas publicitárias de Coca-Cola veiculadas nos dois magazines procuraram se adequar aos discursos de valorização da industrialização brasileira. Com o objetivo de evidenciar o auxílio da Coca-Cola no processo industrialização e desenvolvimento do Brasil

  7. Categorization of the best practices of oil movement and storage according to its internal losses base structure, aiding to define solutions to the increase of the reliability in the area; Categorizacao das boas praticas da transferencia e estocagem do petroleo, de acordo com a estrutura de sua base de perdas interna, subsidiando a definicao de solucoes para o aumento da confiabilidade do setor

    Energy Technology Data Exchange (ETDEWEB)

    Carelli, Alain Cognac; Smarcaro, Joanna; Versiani, Bernardo; Caulliraux, Heitor [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Escola Politecnica. Grupo de Producao Integrada; Lima, Mario Jorge; Warrak, Jorge Alam [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    2008-07-01

    Nowadays, in the dynamic and globalized context that have been verified by petroleum and gas industry, the competitiveness behind the organizations depends on its capacity more and more. It is important to promote the company's employees creative power to set up the solutions for the problems that are found in the organization. These problems should be well defined, diagnosing recent operational routine. In ambit of the Oil Movement and Storage Sector of the refinery, it was developed a tool which turns into possible to evaluate the historic problems which have occurred along years. This tool permits also make cause-effect diagrams and temporal graphics that are stratified by occurrences standard characteristics. These diagrams and graphics structure information, matching them with the undesired events diagnostics and aiding the decision maker to understand about the problem systematic. After the needs that should be attacked are defined toward increase the level of sector reliability, it should study the possible solutions. In agreement of these solutions, there is a reference model that contemplates the best practices of this sector. This model enables the identification of possible solutions for problems that were found in this sector. The Oil Movement and Storage Sector Best Practices Manual involve a conjunct of found recommendations and solutions that can be utilized to improve the sector operational performance. (author)

  8. Seleção de linhagens de feijão rosinha de boa cocção, resistentes à antracnose e mancha angular Selection of pink grain common bean lines with good cooking ability, resistance to anthracnose and angular leaf spot

    Directory of Open Access Journals (Sweden)

    Diego Velásquez Faleiro e Silva

    2009-09-01

    Full Text Available Cultivares de feijoeiro com grão rosinha foram de grande importância, no passado, e ainda hoje, mesmo com a preferência pelo grão carioca, há nichos de mercado para feijões do grupo Rosinha. Dessa forma, o objetivo do trabalho foi selecionar linhagens de feijoeiro comum com grão rosinha, alta produção de grãos, rápido cozimento e resistentes à antracnose e à mancha angular. A partir de cinco famílias F8 superiores, provenientes do cruzamento entre os genitores Rosinha Maria da Fé e ESAL 693, foram extraídas 143 linhagens as quais foram avaliadas na safra das águas de 2005/2006 em Lavras (MG. Dessas, manteve-se 99 linhagens que foram avaliadas em Lavras e Lambari (MG, na safra da seca de 2006. As 24 linhagens selecionadas foram novamente avaliadas nos dois locais, no inverno de 2006. Os caracteres avaliados foram produção e tipo de grão, tempo de cocção, reação à mancha angular e também, foi realizado o teste de resistência ao patótipo 65 de Colletotrichum lindemuthianum. Nas linhagens, observaram-se variabilidade genética para todos os caracteres avaliados, altas estimativas dos coeficientes de herdabilidade, assegurando elevados ganhos com a seleção. Foram selecionadas quatro linhagens com alta produção, tipo de grão ideal, com rápido tempo de cocção e resistência à mancha angular e à antracnose.Common bean cultivars with pink grain type used to be very important, although there is still some market spot for them. The objective of the research was to select common bean lines with pink grain, high grain yield with good cooking ability, and resistance to anthracnose and angular leaf spot. One hundred and forty three lines were selected from five F8 segregant families derived from the cross Rosinha Maria da Fé x ESAL 693. Those lines were evaluated in the rainy season of 2005/2006 at Lavras county, MG State. Ninety nine lines were kept and tested in the dry season of 2006 at Lavras and Lambari. The 24 selected lines were again evaluated in the same last sites in the winter/spring of 2006. Traits recorded included grain yield, grain type, cooking time, angular leaf spot reaction, and resistance test against the pathotype 65 of Colletotrichum lindemuthianum. The lines were genetically different for all traits as confirmed by the high estimates of heritability, assuring high selection gains. Four lines were selected with high grain yield and ideal pink type plus good cooking ability and resistance to anthracnose and angular leaf spot.

  9. A força de preensão manual é boa preditora do desempenho funcional de idosos frágeis: um estudo correlacional múltiplo The hand-grip forecasts the functional performance of fragile elder subjects: a multiple-correlation study

    Directory of Open Access Journals (Sweden)

    Amandio A.R. Geraldes

    2008-02-01

    Full Text Available A força de preensão manual (FPM associa-se com a funcionalidade de idosos, mas há dúvidas sobre o valor dessa relação em todas as situações. O estudo observou a correlação entre FPM de idosos residentes em instituições de cuidados permanentes (asilos e o desempenho funcional (DF em tarefas específicas e inespecíficas para as mãos. Participaram 12 homens (70±6 anos; 64±9 kg; 160±10 cm e sete mulheres (77±11 anos; 49±10 kg; 147±10 cm. A FPM foi medida com dinamômetro hidráulico. As tarefas motoras propostas foram: caminhar 10 m na velocidade máxima (C10, timed up & go test (TUGT, colocar e retirar chave de fechadura (TCCF e tirar e recolocar lâmpada em um bocal (TCLB. O teste de Wilcoxon revelou que os homens apresentaram melhores desempenhos que as mulheres em todos as medidas, exceto IMC, TCCF e TCLB (pHand-grip strength (HGS has been used to predict functional limitation in the elderly. However, this relationship in all situations is doubtful. The purpose of the study was to observe the association between HGS and functional performance (FP, in specific and not specific tasks among 19 long-term home elderly residents, 12 men (70±6 yrs; 64±9 kg; 160±10 cm and 7 women (77±11 yrs; 49±10 kg; 147±10 cm. HGS was measured by a hydraulic hand dynamometer. The FP was measured by the time to perform the following tasks: 1 habitual gait speed (HGS; 2 timed up & go test (TUGT; 3 opening a lock with a key (OLK; 4 to take off and put in a light bulb (TPB. The Wilcoxon test revealed that men were better than women in all measurements except for the IMC, OLK and TPL (p<0.05. The Spearman coefficients showed significant correlation between HGS and three FP tests: TPL (r=-.54; p=.018; TUGT (r=-.67; p=.002 and HGS (r=-.69; p=.001. The multiple correlation showed good correlation between the HGS and all FP tests (R=.66; R²=.44; p<.04. These results suggest that HGS may be a good predictor for FP, especially for fragile and institutionalized elderly subjects, having a good potential as an epidemiologic exposition variable to forecast functional performance.

  10. Can professors be socialized in good teaching practices? The case of the Project Visibilidad Socialización Docente de Profesores Universitarios Españoles con Buenas Prácticas Docentes Podem os Professores socializar-se em boas práticas de ensino? O caso do Projeto Visibilidade

    Directory of Open Access Journals (Sweden)

    María Muradás López

    2010-08-01

    Full Text Available The purpose of this study is to analyze the socialization to teaching experience of faculty who participated in the project Visibilidad. The main objective of this project was to obtain knowledge related to teaching from faculty who are considered good teachers in Spanish universities. This knowledge could enlighten how the socialization to teaching occurs as well as insights on how to improve the process. Based on the international literature on socialization to teaching in higher education and using a methodology of generating themes inductively, the experiences of faculty at the beginning of their careers were analyzed. The data was collected using semi-structured interviews. We found that role models of socialization, self-reflection and formal socialization are the most common experiences reported by participants. This suggests that reinforcing these elements deliberately at an institutional level, it is possible to improve the socialization process of new faculty in higher education as well as their teaching practices. El propósito de este estudio es el análisis de la experiencia de socialización docente vivida por los profesores participantes en el proyecto Visibilidad, cuyo objetivo principal fue la extracción del conocimiento experto de docentes señalados como buenos profesores en universidades españolas. El conocimiento experto de estos docentes puede dar luz a cómo hasta ahora se ha producido la socialización docente y pistas de cómo mejorar este proceso. Con base en la literatura internacional sobre socialización en Educación Superior y siguiendo un modelo inductivo de generación de categorías, se analizaron las vivencias en el inicio de la carrera docente de profesores universitarios. Los datos fueron obtenidos de entrevistas semiestructuradas. Se encontró que los modelos de referencia de socialización, la reflexión autodidacta por parte de los profesores, y su formación son los tópicos con más presencia en las experiencias de los docentes entrevistados; esto sugiere que reforzando estos elementos de un modo deliberado a nivel institucional se podría mejorar el proceso de socialización de los profesores noveles de Educación Superior, así como sus prácticas docentes.
    O objetivo deste estudo é a análise das experiências de socialização docente vividas pelos professores que participam do projeto Visibilidade. O objetivo principal desse programa era obter de conhecimento dos professores especializados identificados como bons professores em universidades espanholas. A experiência destes professores podem esclarecer como são os processos de socialização professor e insights sobre como melhorar esses processos. Com base na literatura internacional sobre a socialização no Ensino Superior e um modelo de geração indutiva de categorias, foram analisados as experiências de professores ao inicio das suas carreiras docentes. Os dados foram coletados através de entrevistas semi-estruturadas. Achamos que os modelos de socialização, a auto-reflexão, e socialização formal são os temas com maior presença nas experiências dos professores entrevistados, sugerindo que o fortalecimento desses elementos em um nível institucional pode melhorar o processo de socialização dos professores novatos e as suas práticas de ensino.

  11. Formar bem as mães para criar e educar boas crianças: as revistas portuguesas de educação familiar e a difusão da maternidade científica (1945-1958 - Educate mothers to rear and educate good children: portuguese parenting magazines and the diffusion

    Directory of Open Access Journals (Sweden)

    Carla Cardoso Vilhena

    2014-09-01

    Full Text Available Este artigo tem como principal objetivo contribuir para a compreensão do processo de construção da maternidade científica em Portugal. Neste sentido, foi analisado um conjunto de artigos (n=628, publicados em revistas de educação familiar, entre 1945 e 1958. A análise realizada permitiu compreender que as revistas analisadas contribuem para a difusão da maternidade científica, ou seja, da ideia de que a aquisição de conhecimento científico sobre a criação e educação das crianças é elemento indispensável ao adequado exercício da função maternal. Observou-se, ainda, a existência de diferentes estratégias de educação para a maternidade, às quais está subjacente um elemento de classe, assim como diferentes níveis de adesão, por parte das mulheres, à concepção de maternidade científica.Palavras-chave: maternidade científica, educação para a maternidade, revistas de educação familiar, análise de discurso.EDUCATE MOTHERS TO REAR AND EDUCATE GOOD CHILDREN: PORTUGUESE PARENTING MAGAZINES AND THE DIFFUSION OF SCIENTIFIC MOTHERHOOD (1945-1958 AbstractThis article explores the construction of scientific motherhood in Portugal through the analysis of a set of texts on education for motherhood (n=628 published in Portuguese parenting magazines between 1945 and 1958. Our results show that the diffusion of a particular view of the ideal mother in parenting magazines contributes to the diffusion of a new ideology that stresses the importance of education for motherhood, the ideology of scientific motherhood. It also shows the emergence of different types of educational interventions, shaped by women’s social class, and provides some insight into the extent to which mothers adhere to scientific motherhood.Keywords: scientific motherhood, education for motherhood, parenting magazines, discourse analysis.FORMAR BIEN LAS MADRES PARA CREAR Y EDUCAR NIÑOS BUENOS: LAS REVISTAS PORTUGUÉS PARA PADRES Y LA DIFUSIÓN DE LA MATERNIDAD CIENTÍFICA (1945-1958 ResumenEste artículo tiene como objetivo principal contribuir a la comprensión de la construcción de la maternidad científica en Portugal. En este sentido, se analizó un conjunto de artículos (n=628, publicado en revistas para padres entre 1945 y 1958. El análisis permitió entender que las revistas analizadas contribuyen a la difusión de la maternidad científica, es decir, a la idea de que la adquisición de conocimientos científicos acerca de la formación y educación de los niños es imprescindible para el ejercicio adecuado de la función maternal. Igualmente se observó la existencia de distintas estrategias de educación, según la clase social, así como diferentes niveles de afiliación, para las mujeres, à la concepción de la maternidad científica.Palabras-clave: maternidad científica, educación para la maternidad, revistas para padres, análisis del discurso.BIEN FORMER DES MÈRES POUR CRÉER ET EDUQUER BONS ENFANTS: MAGASINS PORTUGAIS POUR LES PARENTS ET LA DIFFUSION DE LA MATERNITÉ SCIENTIFIQUE (1945-1958 RésuméCet article a comme but de comprendre le processus de construction de la maternité scientifique au Portugal par le biais d’une analyse de 628 articles publiées dans magasins pour les parents entre 1945 et 1958. Les résultats démontrent que les magasins contribuent à la diffusion de la maternité scientifique, c'est l'idée que l'acquisition de connaissances scientifiques sur l'éducation et l'instruction des enfants sont indispensables pour le bon exercice de la fonction maternelle. Nous avons également observé l'existence de différentes stratégies éducatives pour la maternité, déterminée par la classe sociale, ainsi que différents niveaux d'adhésion, chez les femmes, à la conception de la maternité scientifique.Mots-clé: maternité scientifique, l’éducation des mères, magasins pour les parents, analyse du discours.

  12. Comparative study on implementation of management requires from ABNT NBR ISO/IEC 17025; Estudo comparativo de implementacao de requisitos gerenciais da ABNT NBR ISO/TEC 17025 e boas praticas de gestao em laboratorios de calibracao da area de radiacoes ionizantes

    Energy Technology Data Exchange (ETDEWEB)

    Suplino Filho, Carlos Alberto Lucas; Souza, Luciane de Rezende; Oliveira, Estela Maria de, E-mail: clucas@ird.gov.br, E-mail: rluciane@ird.gov.br, E-mail: estela@ird.gov.br [Instituto de Radioprotecao e Dosimetria, (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2014-07-01

    This work was developed in order to emphasize the importance of laboratory management system in the direction and control of the company or institute with regard to the quality of delivery of ionizing radiation service to society. It was developed a comparative study of managerial points of Deming with the managerial requirements of ISO / IEC 17025, which found that the difficulties of the laboratories indicated by nonconformities tracked during audits, are related to specific points cited by Deming. (author)

  13. Effects of Baseplates of Orthodontic Appliances with in situ generated Silver Nanoparticles on Cariogenic Bacteria: A Randomized, Double-blind Cross-over Clinical Trial.

    Science.gov (United States)

    Ghorbanzadeh, Roghayeh; Pourakbari, Babak; Bahador, Abbas

    2015-04-01

    Polymethyl-methacrylate (PMMA) is commonly used primarily for baseplates of orthodontic appliances (BOA). The activities of cariogenic bacteria in biofilm on these surfaces may contribute to dental caries, gingival inflammation and periodontal disease. The PMMA incorporated with nanoparticles of silver (NanoAg-I-PMMA) and NanoAg in situ in PMMA (NanoAg-IS-PMMA) have been shown to control the growth of cariogenic bacteria, but clinical trial of anti-cariogenic application of these novel materials in orthodontics has not been evaluated. The main aim of the study is to compare the clinical effectiveness of using NanoAg-IS-PMMA and NanoAg-I-PMMA for construction of new BOA in inhibiting the planktonic growth and biofilm formation of the cariogenic bacteria. Twenty four patients with a median age of 12.6 years (7-15) harboring Streptococcus mutans, Streptococcus sobrinus and Lactobacillus acidophilus as well as Lactobacillus casei participated in the randomized, double-blind, cross-over study. The experimental BOA, NanoAg-IS-BOA and NanoAg-I-BOA, contained 0.5% w/w NanoAg while the control BOA was standard PMMA. Antibacterial effect of NanoAg-IS-BOA and NanoAg-I-BOA was assessed against test cariogenic bacteria by planktonic and biofilm bacterial cells growth inhibition. The average levels of test cariogenic bacteria in saliva decreased about 2 to 70 fold (30.9-98.4%) compared to baseline depending on the microorganism type and test BOA. Biofilm inhibition analysis demonstrated that NanoAg-I-BOA and NanoAg-IS-BOA inhibited the biofilm of all test bacteria by 20.1 to 79.9% compared to BOA. NanoAg-IS-BOA had a strong anti-biofilm effect against S. mutans, S. sobrinus and L. casei. However, NanoAg-I-BOA showed only slight anti-biofilm effects on test bacteria. Most notably, at all period of the clinical trial, NanoAg-IS-BOA showed a higher antibacterial activity than NanoAg-I-BOA. Based on the novel data that presented here, the NanoAg-IS-BOA had strong antimicrobial

  14. Unilateral microphthalmia or anophthalmia in eight pythons (Pythonidae)

    DEFF Research Database (Denmark)

    Da Silva, Mari-Ann Otkjær; Berthelsen, MF; Wang, T

    2015-01-01

    OBJECTIVE: To provide morphological descriptions of microphthalmia or anophthalmia in eight pythons using microcomputerized tomography (μCT), magnetic resonance imaging (MRI), and histopathology. ANIMALS STUDIED: Seven Burmese pythons (Python bivittatus) and one ball python (P. regius) with clini......OBJECTIVE: To provide morphological descriptions of microphthalmia or anophthalmia in eight pythons using microcomputerized tomography (μCT), magnetic resonance imaging (MRI), and histopathology. ANIMALS STUDIED: Seven Burmese pythons (Python bivittatus) and one ball python (P. regius...... macroscopic anomalies. CONCLUSIONS: Eight pythons with unilateral left-sided microphthalmia or anophthalmia had one normal eye and a left orbit with malformed or incompletely developed ocular structures along with remnants of fetal structures. These cases lend further information to a condition that is often...

  15. AcEST: DK961770 [AcEST

    Lifescience Database Archive (English)

    Full Text Available Gamma-enolase OS=Gallus gallus GN=ENO2 PE=2... 55 2e-09 sp|Q9W7L0|ENOA_PYTRG Alpha-enolase OS=Python regius...FEFFMD 79 E+ID A Y + +I +DVAA EF+ D Sbjct: 229 EAIDKAGYTDKIVIGMDVAASEFYRD 254 >sp|Q9W7L0|ENOA_PYTRG Alpha-enolase OS=Python

  16. Eigenvector Subset Selection Using Bayesian Optimization Algorithm%基于贝叶斯优化算法的脸面特征向量子集选择

    Institute of Scientific and Technical Information of China (English)

    郭卫锋; 林亚平; 罗光平

    2002-01-01

    Eigenvector subset selection is the key to face recognition. In this paper ,we propose ESS-BOA, a newrandomized, population-based evolutionary algorithm which deals with the Eigenvector Subset Selection (ESS)prob-lem on face recognition application. In ESS-BOA ,the ESS problem, stated as a search problem ,uses the BayesianOptimization Algorithm (BOA) as searching engine and the distance degree as the object function to select eigenvec-tor. Experimental results show that ESS-BOA outperforms the traditional the eigenface selection algorithm.

  17. Mutual mortality of great horned owl and southern black racer: a potential risk of raptors preying on snakes

    Science.gov (United States)

    Roger W. Perry; Raymond E. Brown; D. Craig Rudolph

    2001-01-01

    We encountered a dead southern black racer snake (Coluber constrictor priapus) coiled around a dead Great Horned Owl (Bubo virginianus). We suggest the owl was strangled by the snake before the snake did of wounds inflicted by the owl. There are previous reports of intense physical struggle between Great Horned Owls (and...

  18. Recommendations for the delineation of organs at risk in ENT radiotherapy; Recommandations de delineation des organes a risque en radiotherapie ORL

    Energy Technology Data Exchange (ETDEWEB)

    Ali, D.; Halimi, P.; Berges, O.; Deberne, M.; Botti, M.; Giraud, P. [Hopital europeen Georges-Pompidou, Paris (France); Servagi-Vernat, S. [CHUjean-Minjoz, Besancon (France)

    2011-10-15

    Based on a literature survey, the authors propose recommendations for the delineation of the pharyngeal constrictor muscles, inner ear, larynx, buccal cavity, and temporomandibular joint. These recommendations of delineation of organs at risk are related to the functional anatomy of the considered structures, and correspond to volumes used in published surveys on dose-volume toxicity. They are simple and reproducible. Short communication

  19. 78 FR 39307 - National Environmental Policy Act: Implementing Procedures; Addition to Categorical Exclusions...

    Science.gov (United States)

    2013-07-01

    .... Every EA prepared for an injurious species listing under the Act since 1982 (the first rule promulgated..., 2007), and four species of large constrictor snakes (Burmese python (Python molurus), Northern African python (Python sebae), Southern African python (Python natalensis), and yellow anaconda (Eunectes notaeus...

  20. Recommendations for the delineation of organs at risk in ENT radiotherapy

    International Nuclear Information System (INIS)

    Ali, D.; Halimi, P.; Berges, O.; Deberne, M.; Botti, M.; Giraud, P.; Servagi-Vernat, S.

    2011-01-01

    Based on a literature survey, the authors propose recommendations for the delineation of the pharyngeal constrictor muscles, inner ear, larynx, buccal cavity, and temporomandibular joint. These recommendations of delineation of organs at risk are related to the functional anatomy of the considered structures, and correspond to volumes used in published surveys on dose-volume toxicity. They are simple and reproducible. Short communication

  1. Diet of the Louisiana pine snake (Pituophis ruthveni)

    Science.gov (United States)

    D. Craig Rudolph; Christopher A. Melder; Josh Pierce; Richard R. Schaefer; Beau Gregory

    2012-01-01

    The Louisiana Pine Snake (Pituophis ruthveni) is a large-bodied constrictor endemic to western Louisiana and eastern Texas (Sweet and Parker 1991). Surveys suggest that the species has declined in recent decades and is now restricted to isolated habitat patches (Reichling 1995; Rudolph et al. 2006). Pituophis ruthveni is listed as...

  2. Gastro-intestinale chirurgie en gastro-enterologie. VII. Motiliteitsstoornissen proximaal in de tractus digestivus

    NARCIS (Netherlands)

    Boeckxstaens, G. E.; Busch, O. R.; Akkermans, L. M.; Cuesta, M. A.

    2000-01-01

    Dysphagia and chest pain are the two commonest symptoms of abnormalities of oesophageal motility. Dysphagia is to be distinguished into high or oropharyngeal and low or oesophageal dysphagia. Oropharyngeal dysphagia pertains to dysfunction of the pars cricopharyngea of the M. constrictor pharyngis

  3. Dosimetric Factors Associated With Long-Term Dysphagia After Definitive Radiotherapy for Squamous Cell Carcinoma of the Head and Neck

    International Nuclear Information System (INIS)

    Caudell, Jimmy J.; Schaner, Philip E.; Desmond, Renee A.; Meredith, Ruby F.; Spencer, Sharon A.; Bonner, James A.

    2010-01-01

    Purpose: Intensification of radiotherapy and chemotherapy for head-and-neck cancer may lead to increased rates of dysphagia. Dosimetric predictors of objective findings of long-term dysphagia were sought. Methods and Materials: From an institutional database, 83 patients were identified who underwent definitive intensity-modulated radiotherapy for squamous cell carcinoma of the head and neck, after exclusion of those who were treated for a second or recurrent head-and-neck primary lesion, had locoregional recurrence at any time, had less than 12 months of follow-up, or had postoperative radiotherapy. Dosimetric parameters were analyzed relative to three objective endpoints as a surrogate for severe long-term dysphagia: percutaneous endoscopic gastrostomy (PEG) tube dependence at 12 months, aspiration on modified barium swallow, or pharyngoesophageal stricture requiring dilation. Results: Mean dose greater than 41 Gy and volume receiving 60 Gy (V 60 ) greater than 24% to the larynx were significantly associated with PEG tube dependence and aspiration. V 60 greater than 12% to the inferior pharyngeal constrictor was also significantly associated with increased PEG tube dependence and aspiration. V 65 greater than 33% to the superior pharyngeal constrictor or greater than 75% to the middle pharyngeal constrictor was associated with pharyngoesophageal stricture requiring dilation. Conclusions: Doses to the larynx and pharyngeal constrictors predicted long-term swallowing complications, even when controlled for other clinical factors. The addition of these structures to intensity-modulated radiotherapy optimization may reduce the incidence of dysphagia, although cautious clinical validation is necessary.

  4. Salt, Blood Pressure and Cardiovascular Changes in Human and ...

    African Journals Online (AJOL)

    Salt, Blood Pressure and Cardiovascular Changes in Human and Experimental Studies – A Review. ... Some of the pathophysiological changes include cardiac hypertrophy and enhanced cardiac contractility, enhanced contraction of blood vessels and veins in response to constrictor agonists and diminished relaxation of ...

  5. Influence of amino acids on the phytotoxicity of 2-benzoxazolinone on Lemna paucicostata

    Science.gov (United States)

    2-Benzoxazolinone (BOA) is a phytotoxic compound that induces strong effects on plant metabolism. BOA effects include increased membrane permeability, degradation of proteins and pigments, increased lipid peroxidation, oxidative stress and senescence induction. In this work, the effects of amino aci...

  6. Snake Train

    Institute of Scientific and Technical Information of China (English)

    李鲁

    1993-01-01

    The Parisian Transit Authority (RATP) has beguntesting a new train it hopes will be the 'metro① of theyear 2000': a 150-foot-long continuous tube dubbed② the'Boa.' The train is not sectioned off into cars③, thusallowing as many as 890 passengers to walk from one endof the Boa to the other. Swiveling axles beneath the train

  7. Analysis of borrowing and repayment of credit among livestock ...

    African Journals Online (AJOL)

    This study examined borrowing and repayment of credit among livestock farmers in Cross River State, Nigeria. Data for the study was obtained from the Bank of Agriculture (BOA), Calabar. Descriptive statistics such as percentage count, mean and tables were employed in the analysis. It was discovered that BOA in ...

  8. Kauni vaatega villa / Jaan Mettik

    Index Scriptorium Estoniae

    Mettik, Jaan

    2008-01-01

    Kauni vaatega villast - Quinta da Boa Vista - Madeiral, orhideeaiandist. Omaniku Betty Gartoni pojal Patrick Gartonil oli Westminsteri näitusehallis väljas Quinta da Boa Vista orhideekollektsioonil põhinev akvarelliseeria ning Briti Kuninglik Aiandusselts tunnustas teda kuldmedaliga

  9. Cooperated Bayesian algorithm for distributed scheduling problem

    Institute of Scientific and Technical Information of China (English)

    QIANG Lei; XIAO Tian-yuan

    2006-01-01

    This paper presents a new distributed Bayesian optimization algorithm (BOA) to overcome the efficiency problem when solving NP scheduling problems.The proposed approach integrates BOA into the co-evolutionary schema,which builds up a concurrent computing environment.A new search strategy is also introduced for local optimization process.It integrates the reinforcement learning(RL) mechanism into the BOA search processes,and then uses the mixed probability information from BOA (post-probability) and RL (pre-probability) to enhance the cooperation between different local controllers,which improves the optimization ability of the algorithm.The experiment shows that the new algorithm does better in both optimization (2.2%) and convergence (11.7%),compared with classic BOA.

  10. Liderando mejoras de calidad mediante el desarrollo, implementación, y medición de las guías de buenas prácticas de Enfermería / Leading Quality Improvement through Best Practice Guideline Development, Implementation, and Measurement Science / Liderando com melhor qualidade por meio da elaboração, implementação e avaliação de guias de boas práticas na enfermagem

    OpenAIRE

    Irmajean Bajnok, RN., MScN., PhD.; Doris Grinspun, RN., MSN., PhD., LLD (Hon)., O.ONT.; Monique Lloyd, RN., PhD.; Heather McConnell, RN., BScN., MA(Ed).

    2015-01-01

    Introducción: La búsqueda de prácticas basadas en la evidencia ha estimulado acciones por parte de un número de grupos a nivel mundial para desarrollar herramientas de conocimiento. Sin embargo, la absorción de conocimiento y la implementación de guías de práctica clínica en cualquier ambiente clínico requieren más que la concientización y distribución de guías desarrolladas rigurosamente. Objetivo: El objetivo de este artículo es compartir la implementación de estrategias exitosas desarrolla...

  11. Identification of Burkholderia mallei and Burkholderia pseudomallei adhesins for human respiratory epithelial cells

    Directory of Open Access Journals (Sweden)

    Hogan Robert J

    2010-09-01

    Full Text Available Abstract Background Burkholderia pseudomallei and Burkholderia mallei cause the diseases melioidosis and glanders, respectively. A well-studied aspect of pathogenesis by these closely-related bacteria is their ability to invade and multiply within eukaryotic cells. In contrast, the means by which B. pseudomallei and B. mallei adhere to cells are poorly defined. The purpose of this study was to identify adherence factors expressed by these organisms. Results Comparative sequence analyses identified a gene product in the published genome of B. mallei strain ATCC23344 (locus # BMAA0649 that resembles the well-characterized Yersinia enterocolitica autotransporter adhesin YadA. The gene encoding this B. mallei protein, designated boaA, was expressed in Escherichia coli and shown to significantly increase adherence to human epithelial cell lines, specifically HEp2 (laryngeal cells and A549 (type II pneumocytes, as well as to cultures of normal human bronchial epithelium (NHBE. Consistent with these findings, disruption of the boaA gene in B. mallei ATCC23344 reduced adherence to all three cell types by ~50%. The genomes of the B. pseudomallei strains K96243 and DD503 were also found to contain boaA and inactivation of the gene in DD503 considerably decreased binding to monolayers of HEp2 and A549 cells and to NHBE cultures. A second YadA-like gene product highly similar to BoaA (65% identity was identified in the published genomic sequence of B. pseudomallei strain K96243 (locus # BPSL1705. The gene specifying this protein, termed boaB, appears to be B. pseudomallei-specific. Quantitative attachment assays demonstrated that recombinant E. coli expressing BoaB displayed greater binding to A549 pneumocytes, HEp2 cells and NHBE cultures. Moreover, a boaB mutant of B. pseudomallei DD503 showed decreased adherence to these respiratory cells. Additionally, a B. pseudomallei strain lacking expression of both boaA and boaB was impaired in its ability to

  12. Bibliographie

    OpenAIRE

    2017-01-01

    I. LES DIEUX LITTERATURE PRIMAIRE : LES PRINCIPAUX TEXTES ET LEURS TRADUCTIONS FRANÇAISES A) Edda poétique Traduction française : Régis Boyer, L’Edda poétique, Fayard, Paris 1992. Traduction allemande : Edda. Die Lieder des Codex Regius nebst verwandten Denkmälern. Herausgegeben von Gustav Neckel. I. Text. Hans Kuhn, Heidelberg, 1962. Traduction anglaise: The Poetic Edda, éd. U. Dronke, Oxford, 1969. B) Edda de Snorri Traduction française (partielle) : François-Xavier Dillmann, L’Edda. Récits...

  13. NHE-1 sequence and expression in toad, snake and fish red blood cells

    DEFF Research Database (Denmark)

    Thomsen, Steffen Nyegaard; Wang, Tobias; Kristensen, Torsten

    Red blood cells (RBC) from reptiles appear not to express regulatory volume increase (RVI) upon shrinkage (Kristensen et al., 2008). In other vertebrates, the RVI response is primarily mediated by activation of the Na+/H+ exchanger (NHE-1) and we, therefore decided to investigate whether red cells...... of reptiles express a different NHE-1 that responds less to volume activation compared to other vertebrates or simply lack the Na+/H+ exchanger. Using various tissues from the ball python (Python regius), Cane toad (Bufo marinus) and European perch (Perca fluviatilis), cDNA libraries were created...

  14. Estructura y variación estacional de poblaciones de moluscos asociadas a la pesca artesanal de langosta en el Pacífico Tropical

    Directory of Open Access Journals (Sweden)

    Celia Olabarria

    1999-12-01

    Full Text Available En este trabajo se estudió la fauna malacológica asociada a la pesca de la langosta en aguas del Pacífico Tropical durante 1997-1998. Se recogieron un total de 1 081 individuos pertenecientes a 11 especies. Las mayores capturas se obtuvieron en otoño de 1997 (28.16% y en verano de 1998 (25.58%. Las especies dominantes fueron H. nigritus (83.10%, C. regius (8.04%, V. caestus (2.12%, C. brassica (1.85% y C. erythrostomus (1.75%, las cuales tienen importancia comercial. Se calculó la relación talla-peso, histogramas de frecuencia de tallas, y la relación de sexos para las especies dominantes. La relación de sexos fue de 1:1, salvo en C. erythrostomus y H. nigritus (2 machos: 1 hembra; en C. regius, C. erythrostomus y V. caestus el crecimiento fue alométrico mientras que en H. nigritus y C. brassica fue isométrico. Solamente, los machos de H. nigritus fueron más grandes que las hembras de la misma especie. Se encontraron diferencias significativas en la distribución de las especies respecto a la profundidad; C. erythrostomus apareció a mayores profundidades mientras que H. nigritus estuvo en zonas más someras. El tamaño de H. nigritus varió con la profundidad, temperatura y localidad.Mollusks associated to the spiny lobster fishery during 1997-1998 in the Tropical Pacific were surveyed. A total of 1 081 specimens of 11 species were collected. The greatest captures were in autumn 1997 (28.16% and summer 1998 (25.58%. Dominant species were Hexaplex nigritus (Philippi 1845 (83.10%, Chicoreus regius (Swainson 1821 (8.04%, Vasum caestus (Broderip 1833 (2.12%, C. brassica (Lamarck 1822 (1.85% and C. erythrostomus (Swainson 1831 (1.75%, which have commercial importance. Weight-height ratio, sex ratio and height frequency histograms were done for dominant species. Sex ratio was 1:1, except for C. erythrostomus and H. nigritus (2 males:1 female; C. regius, C. erythrostomus and V. caestus presented an allometric growth while H. nigritus and C

  15. [The mark of envy: metaphysics and embryology according to Descartes].

    Science.gov (United States)

    Gaudemard, Lynda

    2012-01-01

    This paper explores the interaction between medicine and metaphysics in modern natural philosophy and especially in Descartes' philosophy. I argue that Descartes hypothetical account of birthmarks in connection with his embryology provides an argumentative proof of the metaphysical necessity of a substantial union between mind and body, which however does not threaten his doctrine of the real distinction between these two substances. It would appear that his argument relies on a temporal conception of alethic modalities and provides a new answer to Henricus Regius who in 1641 claimed that, for Descartes, the human being is an ensper accidens.

  16. Experiments on Factors That Influence Muscular Function in Man.

    Science.gov (United States)

    1983-05-25

    Publications resulting from A.F. Contract: The blood pressure response during isometric exercise in fast and slow twitch skeletal muscle in the cat... slow tiwtch muscle in the cat. J.S.Petrofsky and A.R. Lind. Pflugers Arch. 398: 149-154, 1981. The influence of fiber composition, recruitment order and...present indicating that p-adrenergic fibres mediated the vaso- constrictor response to the fatiguing muscles . Others have demonstrated changes in

  17. Sensitivity of hippuran renography in experimental renovascular hypertension

    International Nuclear Information System (INIS)

    Jonker, G.J.; Zeeuw, D. de; Huisman, R.M.; Beekhuis, H.; Piers, D.A.

    1988-01-01

    The aim of this research project was to examine the influence of angiotensin converting enzyme inhibitors on the sensitivity of hippuran renography in case of renovascular hypertension. Dogs are used for the experiments. A new constrictor device has been used for external induction of renal artery stenosis in the dogs. After ACE-inhibition a sensitivity of 100% has been found for small stenosis. Without ACE-inhibition the sensitivity was 50%. 6 refs.; 6 figs

  18. Optimal learning with Bernstein online aggregation

    DEFF Research Database (Denmark)

    Wintenberger, Olivier

    2017-01-01

    batch version achieves the fast rate of convergence log (M) / n in deviation. The BOA procedure is the first online algorithm that satisfies this optimal fast rate. The second order refinement is required to achieve the optimality in deviation as the classical exponential weights cannot be optimal, see...... is shown to be sufficiently small to assert the fast rate in the iid setting when the loss is Lipschitz and strongly convex. We also introduce a multiple learning rates version of BOA. This fully adaptive BOA procedure is also optimal, up to a log log (n) factor....

  19. Tank 12H Acidic Chemical Cleaning Sample Analysis And Material Balance

    International Nuclear Information System (INIS)

    Martino, C. J.; Reboul, S. H.; Wiersma, B. J.; Coleman, C. J.

    2013-01-01

    A process of Bulk Oxalic Acid (BOA) chemical cleaning was performed for Tank 12H during June and July of 2013 to remove all or a portion of the approximately 4400 gallon sludge heel. Three strikes of oxalic acid (nominally 4 wt % or 2 wt %) were used at 55 deg C and tank volumes of 96- to 140-thousand gallons. This report details the sample analysis of a scrape sample taken prior to BOA cleaning and dip samples taken during BOA cleaning. It also documents a rudimentary material balance for the Tank 12H cleaning results

  20. Three-Dimensional Dynamics of Breakout Afterburner Ion Acceleration Using High-Contrast Short-Pulse Laser and Nanoscale Targets

    International Nuclear Information System (INIS)

    Yin, L.; Albright, B. J.; Bowers, K. J.; Fernandez, J. C.; Jung, D.; Hegelich, B. M.

    2011-01-01

    Breakout afterburner (BOA) laser-ion acceleration has been demonstrated for the first time in the laboratory. In the BOA, an initially solid-density target undergoes relativistically induced transparency, initiating a period of enhanced ion acceleration. First-ever kinetic simulations of the BOA in three dimensions show that the ion beam forms lobes in the direction orthogonal to laser polarization and propagation. Analytic theory presented for the electron dynamics in the laser ponderomotive field explains how azimuthal symmetry breaks even for a symmetric laser intensity profile; these results are consistent with recent experiments at the Trident laser facility.

  1. Multi-Group Reductions of LTE Air Plasma Radiative Transfer in Cylindrical Geometries

    Science.gov (United States)

    Scoggins, James; Magin, Thierry Edouard Bertran; Wray, Alan; Mansour, Nagi N.

    2013-01-01

    Air plasma radiation in Local Thermodynamic Equilibrium (LTE) within cylindrical geometries is studied with an application towards modeling the radiative transfer inside arc-constrictors, a central component of constricted-arc arc jets. A detailed database of spectral absorption coefficients for LTE air is formulated using the NEQAIR code developed at NASA Ames Research Center. The database stores calculated absorption coefficients for 1,051,755 wavelengths between 0.04 µm and 200 µm over a wide temperature (500K to 15 000K) and pressure (0.1 atm to 10.0 atm) range. The multi-group method for spectral reduction is studied by generating a range of reductions including pure binning and banding reductions from the detailed absorption coefficient database. The accuracy of each reduction is compared to line-by-line calculations for cylindrical temperature profiles resembling typical profiles found in arc-constrictors. It is found that a reduction of only 1000 groups is sufficient to accurately model the LTE air radiation over a large temperature and pressure range. In addition to the reduction comparison, the cylindrical-slab formulation is compared with the finite-volume method for the numerical integration of the radiative flux inside cylinders with varying length. It is determined that cylindrical-slabs can be used to accurately model most arc-constrictors due to their high length to radius ratios.

  2. Medium power hydrogen arcjet performance

    Science.gov (United States)

    Curran, Francis M.; Bullock, S. R.; Haag, Thomas W.; Sarmiento, Charles J.; Sankovic, John M.

    1991-01-01

    An experimental investigation was performed to evaluate hydrogen arcjet operating characteristics in the range of 1 to 4 kW. A series of nozzles were operated in modular laboratory thrusters to examine the effects of geometric parameters such as constrictor diameter and nozzle divergence angle. Each nozzle was tested over a range of current and mass flow rates to explore stability and performance. In the range of mass flow rates and power levels tested, specific impulse values between 650 and 1250 sec were obtained at efficiencies between 30 and 40 percent. The performance of the two larger half angle (20, 15 deg) nozzles was similar for each of the two constrictor diameters tested. The nozzles with the smallest half angle (10 deg) were difficult to operate. A restrike mode of operation was identified and described. Damage in the form of melting was observed in the constrictor region of all the nozzle inserts tested. Arcjet ignition was also difficult in many tests and a glow discharge mode that prevents starting was identified.

  3. The big squeeze: scaling of constriction pressure in two of the world's largest snakes, Python reticulatus and Python molurus bivittatus.

    Science.gov (United States)

    Penning, David A; Dartez, Schuyler F; Moon, Brad R

    2015-11-01

    Snakes are important predators that have radiated throughout many ecosystems, and constriction was important in their radiation. Constrictors immobilize and kill prey by using body loops to exert pressure on their prey. Despite its importance, little is known about constriction performance or its full effects on prey. We studied the scaling of constriction performance in two species of giant pythons (Python reticulatus and Python molurus bivittatus) and propose a new mechanism of prey death by constriction. In both species, peak constriction pressure increased significantly with snake diameter. These and other constrictors can exert pressures dramatically higher than their prey's blood pressure, suggesting that constriction can stop circulatory function and perhaps kill prey rapidly by over-pressurizing the brain and disrupting neural function. We propose the latter 'red-out effect' as another possible mechanism of prey death from constriction. These effects may be important to recognize and treat properly in rare cases when constrictors injure humans. © 2015. Published by The Company of Biologists Ltd.

  4. RECENT A@VAN€E$ IN THE LABQRATGRY DKAGN@§lS QB ...

    African Journals Online (AJOL)

    Boa: A. Onile |gjegm2001a.;yahoo..con;). Malaria is a ... Several new innovative malaria diagnostic tests called Rapid. Diagnostic Tests ... in Plasmodium falciparum infection and this is better ...... parasites in viva by Real-Time quantitative ...

  5. Validation of Heat-Flux Predictions on the Outer Air Seal of a Transonic Turbine Blade (Preprint)

    National Research Council Canada - National Science Library

    Clark, John P; Polanka, Marc D; Meininger, Matthew; Praisner, Thomas J

    2006-01-01

    .... So, a set of predictions of the heat flux on the Blade Outer Air Seal (BOAS) of a transonic turbine is here validated with time-resolved measurements obtained in a single-stage high pressure turbine rig...

  6. Expedient

    Directory of Open Access Journals (Sweden)

    Fernando de Assis Rodrigues

    2017-07-01

    Full Text Available Expedient of Volume 3, Issue 1 from the year 2017EDITORIAL STAFFEditorsDiana Vilas Boas Souto AleixoFernando de Assis RodriguesEditorial ComissionDiana Vilas Boas Souto AleixoFernando de Assis RodriguesRicardo César Gonçalves Sant’AnaExecutive ComissionPedro Henrique Santos BisiAd hoc peer reviewersAna Carolina Simionato, Universidade Federal de São Carlos (UFSCarDiana Vilas Boas Souto Aleixo, Universidade Estadual Paulista (UNESPElaine Parra Affonso, Faculdade de Tecnologia de Presidente Prudente (FATEC - Universidade Estadual Paulista (UNESPElvio Gilberto da Silva, Universidade do Sagrado Coração (USCFábio Mosso Moreira, Universidade Estadual Paulista (UNESPThais Batista Zanineli, Universidade Estadual de Londrina (UELText reviewersDiana Vilas Boas Souto Aleixo, Universidade Estadual Paulista (UNESPElizabete Cristina de Souza Aguiar Monteiro (UNESP

  7. The Big Optical Array

    International Nuclear Information System (INIS)

    Mozurkewich, D.; Johnston, K.J.; Simon, R.S.

    1990-01-01

    This paper describes the design and the capabilities of the Naval Research Laboratory Big Optical Array (BOA), an interferometric optical array for high-resolution imaging of stars, stellar systems, and other celestial objects. There are four important differences between the BOA design and the design of Mark III Optical Interferometer on Mount Wilson (California). These include a long passive delay line which will be used in BOA to do most of the delay compensation, so that the fast delay line will have a very short travel; the beam combination in BOA will be done in triplets, to allow measurement of closure phase; the same light will be used for both star and fringe tracking; and the fringe tracker will use several wavelength channels

  8. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    TOA) and bottom of the atmosphere (BOA) are estimated using a hybrid approach, making use of discrete ordinate radiative transfer method in conjunction with the short-wave flux and spectral aerosol optical depth (AOD) measurements, over a ...

  9. Transit boardings estimation and simulation tool (TBEST) calibration for guideway and BRT modes : [summary].

    Science.gov (United States)

    2013-06-01

    As demand for public transportation grows, planning tools used by Florida Department of Transportation (FDOT) and other transit agencies must evolve to effectively predict changing patterns of ridership. A key tool for this purpose is the Transit Boa...

  10. 76 FR 47947 - Re-Proposal of Shelf Eligibility Conditions for Asset-Backed Securities

    Science.gov (United States)

    2011-08-05

    .... Securities and Exchange Commission Before the Senate Committee on Banking, Housing and Urban Affairs...); Australian Securitisation Forum (AusSF); Bank of America (BOA); CNH Capital America (CNH); Financial Services...

  11. Commonwealth of Pennsylvania Bureau of Aviation pavement evaluation report : final report, March 2010.

    Science.gov (United States)

    2010-03-01

    As part of the Pennsylvania Department of Transportations (PennDOT) airport pavement management efforts, the Bureau of : Aviation (BOA) retained Applied Pavement Technology, Inc. (APTech), assisted by DY Consultants, to evaluate the condition of t...

  12. The Egg with Two Yellows

    Indian Academy of Sciences (India)

    Srimath

    James Watson, Seymour Benzer's work and his place in the .... A graduate student, Ronald J Konopka from. Dayton, joined him, hoping .... genetics of Thomas Hunt Morgan and his student Alfred ... the findings of Franz Boas, Frank A Brown Jr,.

  13. Distinguishing the Effects of Bond-Length Alternation versus Bond-Order Alternation on the Nonlinear Optical Properties of π-Conjugated Chromophores

    KAUST Repository

    Gieseking, Rebecca L.; Risko, Chad; Bredas, Jean-Luc

    2015-01-01

    Understanding the relationships between the molecular nonlinear optical (NLO) properties and the bond-length alternation (BLA) or π-bond-order alternation (BOA) along the molecular backbone of linear π-conjugated systems has proven widely useful in the development of NLO organic chromophores and materials. Here, we examine model polymethines to elucidate the reliability of these relationships. While BLA is solely a measure of molecular geometric structure, BOA includes information pertaining to the electronic structure. As a result, BLA is found to be a good predictor of NLO properties only when optimized geometries are considered, whereas BOA is more broadly applicable. Proper understanding of the distinction between BLA and BOA is critical when designing computational studies of NLO properties, especially for molecules in complex environments or in nonequilibrium geometries. © 2015 American Chemical Society.

  14. Distinguishing the Effects of Bond-Length Alternation versus Bond-Order Alternation on the Nonlinear Optical Properties of π-Conjugated Chromophores

    KAUST Repository

    Gieseking, Rebecca L.

    2015-06-18

    Understanding the relationships between the molecular nonlinear optical (NLO) properties and the bond-length alternation (BLA) or π-bond-order alternation (BOA) along the molecular backbone of linear π-conjugated systems has proven widely useful in the development of NLO organic chromophores and materials. Here, we examine model polymethines to elucidate the reliability of these relationships. While BLA is solely a measure of molecular geometric structure, BOA includes information pertaining to the electronic structure. As a result, BLA is found to be a good predictor of NLO properties only when optimized geometries are considered, whereas BOA is more broadly applicable. Proper understanding of the distinction between BLA and BOA is critical when designing computational studies of NLO properties, especially for molecules in complex environments or in nonequilibrium geometries. © 2015 American Chemical Society.

  15. The effect of percutaneous transmyocardial laser revascularization on left ventricular function in a porcine model of hibernating myocardium

    International Nuclear Information System (INIS)

    Almeda, Francis Q.; Glock, Dana; Sandelski, Joanne; Ibrahim, Osama; Macioch, James E.; Allen, Trisha; Dainauskas, John R.; Parrillo, Joseph E.; Snell, R. Jeffrey; Schaer, Gary L.

    2004-01-01

    Background: Hibernating myocardium is defined as a state of persistently impaired myocardial function at rest due to reduced coronary blood flow that can partially or completely be restored to normal if the myocardial oxygen supply/demand relationship is favorably altered. Percutaneous laser revascularization (PMR) is an emerging catheter-based technique that involves creating channels in the myocardium, directly through a percutaneous approach with a laser delivery system, and has been shown to reduce symptoms in patients with severe refractory angina; however, its effect on improving regional wall motion abnormalities in hibernating myocardium has not been clearly established. We sought to determine the effect of PMR using the Eclipse System (Cardiogenesis) on left ventricular function in a porcine model of hibernating myocardium. Methods: A model of hibernating myocardium was created by placement of an ameroid constrictor in the proximal left anterior descending artery of a 35 kg male Yorkshire pig. The presence of hibernating myocardium was confirmed with dobutamine stress echocardiography (DSE) and defined as severe hypocontractility at rest, with an improvement in systolic wall thickening with low-dose dobutamine in myocardial regions with a subsequent deterioration in function at peak stress (biphasic response). After the demonstration of hibernating myocardium, PMR was performed in the area of hypocontractile function, and the serial echocardiography was performed. The echocardiograms were reviewed by an experienced echocardiologist blinded to the results, and regional wall motion was assessed using the American Society of Echocardiography Wall Motion Score. Six weeks after PMR, the animal was sacrificed and the heart sent for histopathologic studies. Results: A comparison of the regional wall motion function of the area distal to the ameroid constrictor and in the contralateral wall at baseline, post-ameroid placement, and post-PMR was performed

  16. Tratamento cirúrgico do divertículo de Zenker: diverticulopexia versus diverticulectomia Surgical treatment of Zenker diverticulum: diverticulopexy versus diverticulectomy

    Directory of Open Access Journals (Sweden)

    Nelson Adami Aandreollo

    2007-12-01

    Full Text Available RACIONAL: Divertículo faringoesofágico, conhecido como de Zenker, é herniação adquirida na mucosa faríngea através de um defeito muscular entre as fibras oblíquas do músculo constritor inferior da faringe e as transversas do músculo cricofaríngeo. OBJETIVO: estudo retrospectivo, não randomizado, compararando os resultados da diverticulopexia e diverticulectomia, ambas associadas à miotomia do músculo cricofaríngeo, no tratamento do divertículo de Zenker. MÉTODOS: Quarenta pacientes foram submetidos a tratamento cirúrgico entre 1989 e 2003, dos quais 38 (95% foram seguidos. Vinte e oito eram do sexo masculino (70% e 12 femininos, com média de idade de 62,5 anos (21 a 85 anos. Vinte e quatro pacientes (60% foram submetidos à diverticulopexia ou elevação, e 16 à diverticulectomia ou ressecção, através de cervicotomia esquerda, com miotomia do músculo cricofaríngeo. RESULTADOS: Resultados excelentes (Visick I, foram verificados em 84,6% dos pacientes submetidos à diverticulectomia e 66,6% dos pacientes submetidos à diverticulopexia. Na análise global de todos os casos estudados, 27 (11 ressecções e 16 elevações - 72,9% apresentaram Visick I; 8 (2 ressecções e 6 elevações - 21,6% apresentaram Visick II; e 2 (elevações - 5,4% apresentaram Visick III. Não foi registrado nenhum caso na classificação de Visick IV. A incidência de complicações pós-operatórias registrada nos dois grupos foi semelhante (P>0,05. Foi verificado a presença de neoplasia maligna em um caso submetido a ressecção (2,5%. CONCLUSÃO: A diverticulopexia com miotomia do músculo cricofaríngeo é mais indicada em doentes geriátricos, pequenos divertículos e doentes com risco operatório elevado. A diverticulectomia é boa opção em grandes divertículos e doentes jovens, para prevenir o risco de transformação maligna. Esta casuística mostrou melhores resultados com a diverticulectomia em comparação com a diverticulopexia

  17. Representation of complex vocalizations in the Lusitanian toadfish auditory system: evidence of fine temporal, frequency and amplitude discrimination

    Science.gov (United States)

    Vasconcelos, Raquel O.; Fonseca, Paulo J.; Amorim, M. Clara P.; Ladich, Friedrich

    2011-01-01

    Many fishes rely on their auditory skills to interpret crucial information about predators and prey, and to communicate intraspecifically. Few studies, however, have examined how complex natural sounds are perceived in fishes. We investigated the representation of conspecific mating and agonistic calls in the auditory system of the Lusitanian toadfish Halobatrachus didactylus, and analysed auditory responses to heterospecific signals from ecologically relevant species: a sympatric vocal fish (meagre Argyrosomus regius) and a potential predator (dolphin Tursiops truncatus). Using auditory evoked potential (AEP) recordings, we showed that both sexes can resolve fine features of conspecific calls. The toadfish auditory system was most sensitive to frequencies well represented in the conspecific vocalizations (namely the mating boatwhistle), and revealed a fine representation of duration and pulsed structure of agonistic and mating calls. Stimuli and corresponding AEP amplitudes were highly correlated, indicating an accurate encoding of amplitude modulation. Moreover, Lusitanian toadfish were able to detect T. truncatus foraging sounds and A. regius calls, although at higher amplitudes. We provide strong evidence that the auditory system of a vocal fish, lacking accessory hearing structures, is capable of resolving fine features of complex vocalizations that are probably important for intraspecific communication and other relevant stimuli from the auditory scene. PMID:20861044

  18. Blood parasites in reptiles imported to Germany.

    Science.gov (United States)

    Halla, Ursula; Ursula, Halla; Korbel, Rüdiger; Rüdiger, Korbel; Mutschmann, Frank; Frank, Mutschmann; Rinder, Monika; Monika, Rinder

    2014-12-01

    Though international trade is increasing, the significance of imported reptiles as carriers of pathogens with relevance to animal and human health is largely unknown. Reptiles imported to Germany were therefore investigated for blood parasites using light microscopy, and the detected parasites were morphologically characterized. Four hundred ten reptiles belonging to 17 species originating from 11 Asian, South American and African countries were included. Parasites were detected in 117 (29%) of individual reptiles and in 12 species. Haemococcidea (Haemogregarina, Hepatozoon, Schellackia) were found in 84% of snakes (Python regius, Corallus caninus), 20% of lizards (Acanthocercus atricollis, Agama agama, Kinyongia fischeri, Gekko gecko) and 50% of turtles (Pelusios castaneus). Infections with Hematozoea (Plasmodium, Sauroplasma) were detected in 14% of lizards (Acanthocercus atricollis, Agama agama, Agama mwanzae, K. fischeri, Furcifer pardalis, Xenagama batillifera, Acanthosaura capra, Physignathus cocincinus), while those with Kinetoplastea (Trypanosoma) were found in 9% of snakes (Python regius, Corallus caninus) and 25 % of lizards (K. fischeri, Acanthosaura capra, G. gecko). Nematoda including filarial larvae parasitized in 10% of lizards (Agama agama, Agama mwanzae, K. fischeri, Fu. pardalis, Physignathus cocincinus). Light microscopy mostly allowed diagnosis of the parasites' genus, while species identification was not possible because of limited morphological characteristics available for parasitic developmental stages. The investigation revealed a high percentage of imported reptiles being carriers of parasites while possible vectors and pathogenicity are largely unknown so far. The spreading of haemoparasites thus represents an incalculable risk for pet reptiles, native herpetofauna and even human beings.

  19. Como continuaram os processos civilizadores: rumo a uma informalização dos comportamentos e a uma personalidade de terceira natureza

    NARCIS (Netherlands)

    Wouters, Cas|info:eu-repo/dai/nl/069527172

    2012-01-01

    Baseado em uma análise de livros de boas maneiras, datados desde 1890, em quatro países ocidentais, este artigo descreve como "processos civilizadores" continuaram nos séculos XIX e XX. O artigo concentra-se, primeiro, em três funções centrais de uma "boa sociedade" e de seu código de costumes e

  20. 伦敦申奥学北京(英文)

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Beijing, the 2008 Olympic host, has set a good example toLondon's planned bid for the 2012 Olympics, a senior officialof the British Olympic Association (BOA) said recently. Apart from the technical excellence of the Beijing Bid, theclear lesson for the British Government is the necessity of totalgovernment support for the process, BOA Chairman CraigReedie told Xinhua News Agency. The Beijing Bid was outstanding in this regard as everyoneknew that it enjoyed complete government support, addedReedie, ...

  1. Target distribution in cooperative combat based on Bayesian optimization algorithm

    Institute of Scientific and Technical Information of China (English)

    Shi Zhifu; Zhang An; Wang Anli

    2006-01-01

    Target distribution in cooperative combat is a difficult and emphases. We build up the optimization model according to the rule of fire distribution. We have researched on the optimization model with BOA. The BOA can estimate the joint probability distribution of the variables with Bayesian network, and the new candidate solutions also can be generated by the joint distribution. The simulation example verified that the method could be used to solve the complex question, the operation was quickly and the solution was best.

  2. Benzoxazolinone detoxification by N-Glucosylation: The multi-compartment-network of Zea mays L.

    Science.gov (United States)

    Schulz, Margot; Filary, Barbara; Kühn, Sabine; Colby, Thomas; Harzen, Anne; Schmidt, Jürgen; Sicker, Dieter; Hennig, Lothar; Hofmann, Diana; Disko, Ulrich; Anders, Nico

    2016-01-01

    The major detoxification product in maize roots after 24 h benzoxazolin-2(3H)-one (BOA) exposure was identified as glucoside carbamate resulting from rearrangement of BOA-N-glucoside, but the pathway of N-glucosylation, enzymes involved and the site of synthesis were previously unknown. Assaying whole cell proteins revealed the necessity of H2O2 and Fe(2+) ions for glucoside carbamate production. Peroxidase produced BOA radicals are apparently formed within the extraplastic space of the young maize root. Radicals seem to be the preferred substrate for N-glucosylation, either by direct reaction with glucose or, more likely, the N-glucoside is released by glucanase/glucosidase catalyzed hydrolysis from cell wall components harboring fixed BOA. The processes are accompanied by alterations of cell wall polymers. Glucoside carbamate accumulation could be suppressed by the oxireductase inhibitor 2-bromo-4´-nitroacetophenone and by peroxidase inhibitor 2,3-butanedione. Alternatively, activated BOA molecules with an open heterocycle may be produced by microorganisms (e.g., endophyte Fusarium verticillioides) and channeled for enzymatic N-glucosylation. Experiments with transgenic Arabidopsis lines indicate a role of maize glucosyltransferase BX9 in BOA-N-glycosylation. Western blots with BX9 antibody demonstrate the presence of BX9 in the extraplastic space. Proteomic analyses verified a high BOA responsiveness of multiple peroxidases in the apoplast/cell wall. BOA incubations led to shifting, altered abundances and identities of the apoplast and cell wall located peroxidases, glucanases, glucosidases and glutathione transferases (GSTs). GSTs could function as glucoside carbamate transporters. The highly complex, compartment spanning and redox-regulated glucoside carbamate pathway seems to be mainly realized in Poaceae. In maize, carbamate production is independent from benzoxazinone synthesis.

  3. Implementación de guías de buenas prácticas clínicas elaboradas por Registered Nurses Association of Ontario (RNAO) en el curriculum de Enfermería Universidad de Chile / Implementation of Clinical Best Practice Guidelines Done by The Registered Nurses’ Association of Ontario (RNAO) in the Nursing Curriculum at Universidad de Chile / Implementação de manuais de boas práticas clínicas desenvolvidas por Registered Nurses Association of Ontario (RNAO) no currículo de Enfermagem da Universidade do Chile

    OpenAIRE

    Amalia Silva-G, Lic. en Enf. y Obstetricia, Mg., PhD. (c)

    2015-01-01

    Introducción: La investigación desarrollada en enfermería en el último tiempo ha permitido generar conocimientos que aportan a mejorar el cuidado de salud que otorgan los profesionales, se han confeccionado protocolos y guías clínicas con la finalidad de ofrecer a los profesionales de la salud la mejor evidencia para la práctica clínica, viéndose beneficiadas con ello, principalmente, las personas que requieren cuidados y también las instituciones al disminuir sus costos. Para llegar a esta m...

  4. Impact of Facial Conformation on Canine Health: Brachycephalic Obstructive Airway Syndrome.

    Science.gov (United States)

    Packer, Rowena M A; Hendricks, Anke; Tivers, Michael S; Burn, Charlotte C

    2015-01-01

    The domestic dog may be the most morphologically diverse terrestrial mammalian species known to man; pedigree dogs are artificially selected for extreme aesthetics dictated by formal Breed Standards, and breed-related disorders linked to conformation are ubiquitous and diverse. Brachycephaly--foreshortening of the facial skeleton--is a discrete mutation that has been selected for in many popular dog breeds e.g. the Bulldog, Pug, and French Bulldog. A chronic, debilitating respiratory syndrome, whereby soft tissue blocks the airways, predominantly affects dogs with this conformation, and thus is labelled Brachycephalic Obstructive Airway Syndrome (BOAS). Despite the name of the syndrome, scientific evidence quantitatively linking brachycephaly with BOAS is lacking, but it could aid efforts to select for healthier conformations. Here we show, in (1) an exploratory study of 700 dogs of diverse breeds and conformations, and (2) a confirmatory study of 154 brachycephalic dogs, that BOAS risk increases sharply in a non-linear manner as relative muzzle length shortens. BOAS only occurred in dogs whose muzzles comprised less than half their cranial lengths. Thicker neck girths also increased BOAS risk in both populations: a risk factor for human sleep apnoea and not previously realised in dogs; and obesity was found to further increase BOAS risk. This study provides evidence that breeding for brachycephaly leads to an increased risk of BOAS in dogs, with risk increasing as the morphology becomes more exaggerated. As such, dog breeders and buyers should be aware of this risk when selecting dogs, and breeding organisations should actively discourage exaggeration of this high-risk conformation in breed standards and the show ring.

  5. Impact of Facial Conformation on Canine Health: Brachycephalic Obstructive Airway Syndrome

    Science.gov (United States)

    Packer, Rowena M. A.; Hendricks, Anke; Tivers, Michael S.; Burn, Charlotte C.

    2015-01-01

    The domestic dog may be the most morphologically diverse terrestrial mammalian species known to man; pedigree dogs are artificially selected for extreme aesthetics dictated by formal Breed Standards, and breed-related disorders linked to conformation are ubiquitous and diverse. Brachycephaly–foreshortening of the facial skeleton–is a discrete mutation that has been selected for in many popular dog breeds e.g. the Bulldog, Pug, and French Bulldog. A chronic, debilitating respiratory syndrome, whereby soft tissue blocks the airways, predominantly affects dogs with this conformation, and thus is labelled Brachycephalic Obstructive Airway Syndrome (BOAS). Despite the name of the syndrome, scientific evidence quantitatively linking brachycephaly with BOAS is lacking, but it could aid efforts to select for healthier conformations. Here we show, in (1) an exploratory study of 700 dogs of diverse breeds and conformations, and (2) a confirmatory study of 154 brachycephalic dogs, that BOAS risk increases sharply in a non-linear manner as relative muzzle length shortens. BOAS only occurred in dogs whose muzzles comprised less than half their cranial lengths. Thicker neck girths also increased BOAS risk in both populations: a risk factor for human sleep apnoea and not previously realised in dogs; and obesity was found to further increase BOAS risk. This study provides evidence that breeding for brachycephaly leads to an increased risk of BOAS in dogs, with risk increasing as the morphology becomes more exaggerated. As such, dog breeders and buyers should be aware of this risk when selecting dogs, and breeding organisations should actively discourage exaggeration of this high-risk conformation in breed standards and the show ring. PMID:26509577

  6. Impact of Facial Conformation on Canine Health: Brachycephalic Obstructive Airway Syndrome.

    Directory of Open Access Journals (Sweden)

    Rowena M A Packer

    Full Text Available The domestic dog may be the most morphologically diverse terrestrial mammalian species known to man; pedigree dogs are artificially selected for extreme aesthetics dictated by formal Breed Standards, and breed-related disorders linked to conformation are ubiquitous and diverse. Brachycephaly--foreshortening of the facial skeleton--is a discrete mutation that has been selected for in many popular dog breeds e.g. the Bulldog, Pug, and French Bulldog. A chronic, debilitating respiratory syndrome, whereby soft tissue blocks the airways, predominantly affects dogs with this conformation, and thus is labelled Brachycephalic Obstructive Airway Syndrome (BOAS. Despite the name of the syndrome, scientific evidence quantitatively linking brachycephaly with BOAS is lacking, but it could aid efforts to select for healthier conformations. Here we show, in (1 an exploratory study of 700 dogs of diverse breeds and conformations, and (2 a confirmatory study of 154 brachycephalic dogs, that BOAS risk increases sharply in a non-linear manner as relative muzzle length shortens. BOAS only occurred in dogs whose muzzles comprised less than half their cranial lengths. Thicker neck girths also increased BOAS risk in both populations: a risk factor for human sleep apnoea and not previously realised in dogs; and obesity was found to further increase BOAS risk. This study provides evidence that breeding for brachycephaly leads to an increased risk of BOAS in dogs, with risk increasing as the morphology becomes more exaggerated. As such, dog breeders and buyers should be aware of this risk when selecting dogs, and breeding organisations should actively discourage exaggeration of this high-risk conformation in breed standards and the show ring.

  7. Dosimetric Predictors of Patient-Reported Xerostomia and Dysphagia With Deintensified Chemoradiation Therapy for HPV-Associated Oropharyngeal Squamous Cell Carcinoma.

    Science.gov (United States)

    Chera, Bhishamjit S; Fried, David; Price, Alex; Amdur, Robert J; Mendenhall, William; Lu, Chiray; Das, Shiva; Sheets, Nathan; Marks, Lawrence; Mavroidis, Panayiotis

    2017-08-01

    To estimate the association between different dose-volume metrics of the salivary glands and pharyngeal constrictors with patient reported severity of xerostomia/dysphagia in the setting of deintensified chemoradiation therapy (CRT). Forty-five patients were treated on a phase 2 study assessing the efficacy of deintensified CRT for favorable-risk, HPV-associated oropharyngeal squamous cell carcinoma. Patients received 60 Gy intensity modulated radiation therapy with concurrent weekly cisplatin (30 mg/m 2 ), and reported the severity of their xerostomia/dysphagia (before and after treatment) using the patient-reported outcome version of the Common Terminology Criteria for Adverse Events (CTCAE) (PRO-CTCAE). Individual patient dosimetric data of the contralateral parotid and submandibular glands and pharyngeal constrictors were correlated with changes in PRO-CTCAE severity. A change in severity (from baseline) of ≥2 was considered clinically meaningful. Associations between dose-volume metrics and patient outcomes were assessed with receiver operating characteristic (ROC) curve and logistic regression model. Six months after CRT, patients reporting xerostomia severity (n=14) had an average D mean = 22 ± 9 Gy to the sum of the contralateral glands (parotid + submandibular) compared with the patients reporting ≥2 change (n=21), who had an average D mean = 34 ± 8 Gy. V15 to V55 for the combined contralateral glands showed the strongest association with xerostomia (area under the curve [AUC] = 0.83-0.86). Based on the regression analysis, a 20% risk of toxicity was associated with V15 = 48%, V25 = 30%, and D mean =21 Gy. Six months after CRT, patients reporting xerostomia/dysphagia appears to be associated with the V15 of the combined contralateral salivary glands and V55 to V60 of the superior pharyngeal constrictors. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Can IMRT or Brachytherapy Reduce Dysphagia Associated With Chemoradiotherapy of Head and Neck Cancer? The Michigan and Rotterdam Experiences

    International Nuclear Information System (INIS)

    Eisbruch, Avraham; Levendag, Peter C.; Feng, Felix Y.; Teguh, David; Lyden, Teresa M.A.; Schmitz, Paul I.M.; Haxer, Marc; Noever, Inge; Chepeha, Douglas B.; Heijmen, Ben J.

    2007-01-01

    Purpose: Dysphagia is a major late complication of intensive chemoradiotherapy of head and neck cancer. The initial clinical results of intensity-modulated radiotherapy (IMRT), or brachytherapy, planned specifically to reduce dysphagia are presented. Patients and Methods: Previous research at Michigan University has suggested that the pharyngeal constrictors and glottic and supraglottic larynx are likely structures whose damage by chemo-RT causes dysphagia and aspiration. In a prospective Michigan trial, 36 patients with oropharyngeal (n = 31) or nasopharyngeal (n = 5) cancer underwent chemo-IMRT. IMRT cost functions included sparing noninvolved pharyngeal constrictors and the glottic and supraglottic larynx. After a review of published studies, the retropharyngeal nodes at risk were defined as the lateral, but not the medial, retropharyngeal nodes, which facilitated sparing of the swallowing structures. In Rotterdam, 77 patients with oropharyngeal cancer were treated with IMRT, three dimensional RT, or conventional RT; also one-half received brachytherapy. The dysphagia endpoints included videofluoroscopy and observer-assessed scores at Michigan and patient-reported quality-of-life instruments in both studies. Results: In both studies, the doses to the upper and middle constrictors correlated highly with the dysphagia endpoints. In addition, doses to the glottic and supraglottic larynx were significant in the Michigan series. In the Rotterdam series, brachytherapy (which reduced the doses to the swallowing structures) was the only significant factor on multivariate analysis. Conclusion: The dose-response relationships for the swallowing structures found in these studies suggest that reducing their doses, using either IMRT aimed at their sparing, or brachytherapy, might achieve clinical gains in dysphagia

  9. A Novel Imaging Analysis Method for Capturing Pharyngeal Constriction During Swallowing.

    Science.gov (United States)

    Schwertner, Ryan W; Garand, Kendrea L; Pearson, William G

    2016-01-01

    Videofluoroscopic imaging of swallowing known as the Modified Barium Study (MBS) is the standard of care for assessing swallowing difficulty. While the clinical purpose of this radiographic imaging is to primarily assess aspiration risk, valuable biomechanical data is embedded in these studies. Computational analysis of swallowing mechanics (CASM) is an established research methodology for assessing multiple interactions of swallowing mechanics based on coordinates mapping muscle function including hyolaryngeal movement, pharyngeal shortening, tongue base retraction, and extension of the head and neck, however coordinates characterizing pharyngeal constriction is undeveloped. The aim of this study was to establish a method for locating the superior and middle pharyngeal constrictors using hard landmarks as guides on MBS videofluoroscopic imaging, and to test the reliability of this new method. Twenty de-identified, normal, MBS videos were randomly selected from a database. Two raters annotated landmarks for the superior and middle pharyngeal constrictors frame-by-frame using a semi-automated MATLAB tracker tool at two time points. Intraclass correlation coefficients were used to assess test-retest reliability between two raters with an ICC = 0.99 or greater for all coordinates for the retest measurement. MorphoJ integrated software was used to perform a discriminate function analysis to visualize how all 12 coordinates interact with each other in normal swallowing. The addition of the superior and middle pharyngeal constrictor coordinates to CASM allows for a robust analysis of the multiple components of swallowing mechanics interacting with a wide range of variables in both patient specific and cohort studies derived from common use imaging data.

  10. Molecular Characterization of MYB28 Involved in Aliphatic Glucosinolate Biosynthesis in Chinese Kale (Brassica oleracea var. alboglabra Bailey

    Directory of Open Access Journals (Sweden)

    Ling Yin

    2017-06-01

    Full Text Available Glucosinolates are Brassicaceae-specific secondary metabolites that act as crop protectants, flavor precursors, and cancer-prevention agents, which shows strong evidences of anticarcinogentic, antioxidant, and antimicrobial activities. MYB28, the R2R3-MYB28 transcription factor, directly activates genes involved in aliphatic glucosinolate biosynthesis. In this study, the MYB28 homology (BoaMYB28 was identified in Chinese kale (Brassica oleracea var. alboglabra Bailey. Analysis of the nucleotide sequence indicated that the cDNA of BoaMYB28 was 1257 bp with an ORF of 1020 bp. The deduced BoaMYB28 protein was a polypeptide of 339 amino acid with a putative molecular mass of 38 kDa and a pI of 6.87. Sequence homology and phylogenetic analysis showed that BoaMYB28 was most closely related to MYB28 homologs from the Brassicaceae family. The expression levels of BoaMYB28 varies across the tissues and developmental stages. BoaMYB28 transcript levels were higher in leaves and stems compared with those in cotyledons, flowers, and siliques. BoaMYB28 was expressed across all developmental leaf stages, with higher transcript accumulation in mature and inflorescence leaves. Over-expression and RNAi studies showed that BoaMYB28 retains the basic MYB28 gene function as a major transcriptional regulator of aliphatic glucosinolate pathway. The results indicated that over-expression and RNAi lines showed no visible difference on plant morphology. The contents of aliphatic glucosinolates and transcript levels of aliphatic glucosinolate biosynthesis genes increased in over-expression lines and decreased in RNAi lines. In over-expression lines, aliphatic glucosinolate contents were 1.5- to 3-fold higher than those in the wild-type, while expression levels of aliphatic glucosinolate biosynthesis genes were 1.5- to 4-fold higher than those in the wild-type. In contrast, the contents of aliphatic glucosinolates and transcript levels of aliphatic glucosinolate

  11. Molecular Characterization of MYB28 Involved in Aliphatic Glucosinolate Biosynthesis in Chinese Kale (Brassica oleracea var. alboglabra Bailey).

    Science.gov (United States)

    Yin, Ling; Chen, Hancai; Cao, Bihao; Lei, Jianjun; Chen, Guoju

    2017-01-01

    Glucosinolates are Brassicaceae-specific secondary metabolites that act as crop protectants, flavor precursors, and cancer-prevention agents, which shows strong evidences of anticarcinogentic, antioxidant, and antimicrobial activities. MYB28 , the R2R3-MYB28 transcription factor, directly activates genes involved in aliphatic glucosinolate biosynthesis. In this study, the MYB28 homology ( BoaMYB28 ) was identified in Chinese kale ( Brassica oleracea var. alboglabra Bailey). Analysis of the nucleotide sequence indicated that the cDNA of BoaMYB28 was 1257 bp with an ORF of 1020 bp. The deduced BoaMYB28 protein was a polypeptide of 339 amino acid with a putative molecular mass of 38 kDa and a pI of 6.87. Sequence homology and phylogenetic analysis showed that BoaMYB28 was most closely related to MYB28 homologs from the Brassicaceae family. The expression levels of BoaMYB28 varies across the tissues and developmental stages. BoaMYB28 transcript levels were higher in leaves and stems compared with those in cotyledons, flowers, and siliques. BoaMYB28 was expressed across all developmental leaf stages, with higher transcript accumulation in mature and inflorescence leaves. Over-expression and RNAi studies showed that BoaMYB28 retains the basic MYB28 gene function as a major transcriptional regulator of aliphatic glucosinolate pathway. The results indicated that over-expression and RNAi lines showed no visible difference on plant morphology. The contents of aliphatic glucosinolates and transcript levels of aliphatic glucosinolate biosynthesis genes increased in over-expression lines and decreased in RNAi lines. In over-expression lines, aliphatic glucosinolate contents were 1.5- to 3-fold higher than those in the wild-type, while expression levels of aliphatic glucosinolate biosynthesis genes were 1.5- to 4-fold higher than those in the wild-type. In contrast, the contents of aliphatic glucosinolates and transcript levels of aliphatic glucosinolate biosynthesis genes in

  12. Informed consent and the readability of the written consent form.

    Science.gov (United States)

    Sivanadarajah, N; El-Daly, I; Mamarelis, G; Sohail, M Z; Bates, P

    2017-11-01

    Introduction The aim of this study was to objectively ascertain the level of readability of standardised consent forms for orthopaedic procedures. Methods Standardised consent forms (both in summary and detailed formats) endorsed by the British Orthopaedic Association (BOA) were retrieved from orthoconsent.com and assessed for readability. This involved using an online tool to calculate the validated Flesch reading ease score (FRES). This was compared with the FRES for the National Health Service (NHS) Consent Form 1. Data were analysed and interpreted according to the FRES grading table. Results The FRES for Consent Form 1 was 55.6, relating to the literacy expected of an A level student. The mean FRES for the BOA summary consent forms (n=27) was 63.6 (95% confidence interval [CI]: 61.2-66.0) while for the detailed consent forms (n=32), it was 68.9 (95% CI: 67.7-70.0). All BOA detailed forms scored >60, correlating to the literacy expected of a 13-15-year-old. The detailed forms had a higher FRES than the summary forms (p<0.001). Conclusions This study demonstrates that the BOA endorsed standardised consent forms are much easier to read and understand than the NHS Consent Form 1, with the detailed BOA forms being the easiest to read. Despite this, owing to varying literacy levels, a significant proportion of patients may struggle to give informed consent based on the written information provided to them.

  13. Two Horizontally Transferred Xenobiotic Resistance Gene Clusters Associated with Detoxification of Benzoxazolinones by Fusarium Species

    Science.gov (United States)

    Glenn, Anthony E.; Davis, C. Britton; Gao, Minglu; Gold, Scott E.; Mitchell, Trevor R.; Proctor, Robert H.; Stewart, Jane E.; Snook, Maurice E.

    2016-01-01

    Microbes encounter a broad spectrum of antimicrobial compounds in their environments and often possess metabolic strategies to detoxify such xenobiotics. We have previously shown that Fusarium verticillioides, a fungal pathogen of maize known for its production of fumonisin mycotoxins, possesses two unlinked loci, FDB1 and FDB2, necessary for detoxification of antimicrobial compounds produced by maize, including the γ-lactam 2-benzoxazolinone (BOA). In support of these earlier studies, microarray analysis of F. verticillioides exposed to BOA identified the induction of multiple genes at FDB1 and FDB2, indicating the loci consist of gene clusters. One of the FDB1 cluster genes encoded a protein having domain homology to the metallo-β-lactamase (MBL) superfamily. Deletion of this gene (MBL1) rendered F. verticillioides incapable of metabolizing BOA and thus unable to grow on BOA-amended media. Deletion of other FDB1 cluster genes, in particular AMD1 and DLH1, did not affect BOA degradation. Phylogenetic analyses and topology testing of the FDB1 and FDB2 cluster genes suggested two horizontal transfer events among fungi, one being transfer of FDB1 from Fusarium to Colletotrichum, and the second being transfer of the FDB2 cluster from Fusarium to Aspergillus. Together, the results suggest that plant-derived xenobiotics have exerted evolutionary pressure on these fungi, leading to horizontal transfer of genes that enhance fitness or virulence. PMID:26808652

  14. Faunistic analysis of the species of Anastrepha Schiner (Diptera: Tephritidae in three municipalities of the state of Roraima, Brazil

    Directory of Open Access Journals (Sweden)

    AL. Marsaro Júnior

    Full Text Available The purpose of this work was to describe the population patterns of Anastrepha in three municipalities of the state of Roraima, Brazil, via faunistic analysis. Weekly collections were performed from January through December 2008, using McPhail traps containing 5% hydrolysed protein, in domestic orchards in the municipalities of Boa Vista, Bonfim and Pacaraima. We captured 301 females of Anastrepha in Boa Vista, 212 in Bonfim, and 167 in Pacaraima. Boa Vista presented the highest species richness (S = 10 and Pacaraima the lowest (S = 4. Anastrepha striata was the predominant species in Boa Vista (47.18% and Pacaraima (65.87%, whereas A. obliqua predominated in Bonfim (46.23%. Boa Vista presented the highest Shannon-Wiener diversity index (H' = 1.19 and Margalef index (α = 1.58, and Bonfim presented the highest Pielou's evenness index (J' = 0.69. In Pacaraima the cumulative curves reached stability, confirming that the observed and expected species richness were the same. In the other two municipalities, the curves showed a moderate growth, suggesting that the sampling effort was not sufficient to produce an accurate depiction of species richness. In this study, Anastrepha zernyi is reported for the first time in Roraima.

  15. A two-temperature chemical non-equilibrium modeling of DC arc plasma

    International Nuclear Information System (INIS)

    Qian Haiyang; Wu Bin

    2011-01-01

    To a better understanding of non-equilibrium characteristics of DC arc plasma,a two-dimensional axisymmetric two-temperature chemical non-equilibrium (2T-NCE) model is applied for direct current arc argon plasma generator with water-cooled constrictor at atmospheric pressure. The results show that the electron temperature and heavy particle temperature has a relationship under different working parameters, indicating that DC arc plasma has a strong non-equilibrium characteristic, and the variation is obvious. (authors)

  16. William Osler's "The Nervousness of American Women".

    Science.gov (United States)

    Golden, Richard L

    2008-02-01

    Almost a century ago, William Osler, the foremost physician of his time, was approached by a leading periodical to write a series of articles on the health of the American woman. Osler, then the Regius Professor of Medicine at Oxford, wrote an essay dealing with the psychological stresses affecting the "new woman" of the early 20th century at varying stages of her development and the "nervousness" that ensued. The article was never published as a result of his belated reservations on the propriety of a professional writing for a lay journal. Osler's thinking frequently reflected the spirit of his Victorian-Edwardian era, although at times he demonstrated advanced and prescient ideas about sexuality, not often the subject of discussion, even in circumspect form, in contemporary nonprofessional literature.

  17. Minimal volume regulation after shrinkage of red blood cells from five species of reptiles

    DEFF Research Database (Denmark)

    Kristensen, Karina; Berenbrink, Michael; Koldkjær, Pia

    2008-01-01

    Red blood cells (RBCs) from most vertebrates restore volume upon hypertonic shrinkage and the mechanisms underlying this regulatory volume increase (RVI) have been studied extensively in these cells. Despite the phylogenetically interesting position of reptiles, very little is known about their red...... cell function. The present study demonstrates that oxygenated RBCs in all major groups of reptiles exhibit no or a very reduced RVI upon ~ 25% calculated hyperosmotic shrinkage. Thus, RBCs from the snakes Crotalus durissus and Python regius, the turtle Trachemys scripta and the alligator Alligator...... was not characterized. It seems, therefore, that the RVI response based on NHE activation was lost among the early sauropsids that gave rise to modern reptiles and birds, while it was retained in mammals. An RVI response has then reappeared in birds, but based on activation of the NKCC. Alternatively, the absence...

  18. James Gregory, the University observatory and the early acquisition of scientific instruments at the University of St Andrews

    Science.gov (United States)

    Rawson, Helen C.

    2015-01-01

    James Gregory, inventor of the reflecting telescope and Fellow of the Royal Society, was the first Regius Professor of Mathematics of the University of St Andrews, 1668–74. He attempted to establish in St Andrews what would, if completed, have been the first purpose-built observatory in the British Isles. He travelled to London in 1673 to purchase instruments for equipping the observatory and improving the teaching and study of natural philosophy and mathematics in the university, seeking the advice of John Flamsteed, later the first Astronomer Royal. This paper considers the observatory initiative and the early acquisition of instruments at the University of St Andrews, with reference to Gregory's correspondence, inventories made ca. 1699–ca. 1718 and extant instruments themselves, some of which predate Gregory's time. It examines the structure and fate of the university observatory, the legacy of Gregory's teaching and endeavours, and the meridian line laid down in 1748 in the University Library.

  19. Memories of Ken Mason.

    Science.gov (United States)

    Brazier, Margaret; McCall Smith, Alexander; Laurie, Graeme; McLean, Shelia; Jackson, Emily; Neal, Mary; Biggs, Hazel; Ost, Suzanne

    2017-08-01

    John Kenyon Mason (19 December 1919-26 January 2017), CBE, MD, LLD, FRCPath, DMJ, FRCPE, FRSE, and known as Ken Mason to us all, was Regius Professor of Forensic Medicine at the University of Edinburgh from 1973-1985 and thereafter Emeritus Professor of Forensic Medicine and Honorary Fellow in the School of Law at the University of Edinburgh. A formal obituary to Professor Mason is published in the Scotsman (http://www.scotsman.com/news/obituaries/obituary-professor-ken-mason-medical-jurisprudence-pioneer-1-4357181). We offer some personal tributes to our friend and colleague. © The Author 2017. Published by Oxford University Press; all rights reserved. For Permissions, please email: journals.permissions@oup.com.

  20. Histamine induces postprandian tachycardia through a direct effect on cardiac H2-receptors in pythons

    DEFF Research Database (Denmark)

    Jensen, Nini Skovgaard; Møller, Kate; Gesser, Hans

    2009-01-01

    The intrinsic heart rate of most vertebrates studied, including humans, is elevated during digestion, suggesting that a non-adrenergic-non-cholinergic factor contributes to the postprandial tachycardia. The regulating factor, however, remains elusive and difficult to identify. Pythons can ingest...... very large meals and digestion is associated with a marked rise in metabolism that is sustained for several days. The metabolic rise causes more than a doubling of heart rate and a four-fold rise in cardiac output. This makes the python an interesting model to investigate the postprandial tachycardia....... We measured blood pressure and heart rate in fasting Python regius, and at 24 and 48h after ingestion of a meal amounting to 25% of body weight. Digestion caused heart rate to increase from 25 to 56 min-1 while blood pressure was unchanged. The postprandial rise in heart rate was partially due...

  1. A question of merit: John Hutton Balfour, Joseph Hooker and the 'concussion' over the Edinburgh chair of botany.

    Science.gov (United States)

    Bellon, Richard

    2005-03-01

    In 1845, Robert Graham's death created a vacancy for the traditionally dual appointment to the University of Edinburgh's chair of botany and the Regius Keepership of the Edinburgh Royal Botanic Garden. John Hutton Balfour and Joseph Hooker emerged as the leading candidates. The contest quickly became embroiled in long running controversies over the nature and control of Scottish university education at a time of particular social and political tension after a recent schism in Church of Scotland. The politics of the appointment were complicated by the fact that the Edinburgh Town Council (which preferred Balfour) chose the chair while the keepership was under the patronage of the Westminster government (which preferred Hooker). Balfour eventually emerged triumphant after a bitter campaign marked on all sides by intense politicking. The struggle to replace Graham provides a case study in how Victorian men of science adapted their aspirations to the practical realities of life in industrial, reforming, imperial, multinational Britain.

  2. Descartes and the “metaphysical dualism”: Excesses in interpreting a classic

    Directory of Open Access Journals (Sweden)

    Ştefan Afloroaei

    2010-06-01

    Full Text Available The article focuses on one of the most serious accusations brought against Descartes and modern philosophy, namely “the dualism of substance”. The accusers claim that the human body and soul were viewed as completely separate; consequently, their relationship as such and the united being of man become incomprehensible. As has been shown above, the idea of the separation of the soul from the body did not originate with Descartes; it was formulated much earlier, and repeated by a disciple of Descartes’, Henry Leroy, known as Regius. When Descartes became aware of this bizarre interpretation he was dismayed and sought to clarify the matter. He sought to distinguish between two terms, “distinction” and “separation” and to illuminate the relationship between body and soul at three different levels, i.e. ordinary experience, analytical mind and metaphysical meditation.Eventually, he embraced the paradox of the two natures – the double substantial make-up of the human being, a paradox of patristic inspiration. However, the later history of ideas was not sympathetic to Descartes: nowadays, when one looks up the term “metaphysical dualism” in dictionaries or glossaries, even in the studies of prestigious researchers, one will find views similar to those of the unfaithful disciple Regius. The resilience of this locus obscurus is explained both by the power of a new mode of interpreting discourse (as technical or logical analysis and by the ever more privilegedposition of the reader (intentio lectoris. Both attitudes are related to modern ideologies and to changes which have occurred in the intersubjective lifeworld, especially in the communication of the scholarly and academic world.

  3. Python erythrocytes are resistant to α-hemolysin from Escherichia coli.

    Science.gov (United States)

    Larsen, Casper K; Skals, Marianne; Wang, Tobias; Cheema, Muhammad U; Leipziger, Jens; Praetorius, Helle A

    2011-12-01

    α-Hemolysin (HlyA) from Escherichia coli lyses mammalian erythrocytes by creating nonselective cation pores in the membrane. Pore insertion triggers ATP release and subsequent P2X receptor and pannexin channel activation. Blockage of either P2X receptors or pannexin channels reduces HlyA-induced hemolysis. We found that erythrocytes from Python regius and Python molurus are remarkably resistant to HlyA-induced hemolysis compared to human and Trachemys scripta erythrocytes. HlyA concentrations that induced maximal hemolysis of human erythrocytes did not affect python erythrocytes, but increasing the HlyA concentration 40-fold did induce hemolysis. Python erythrocytes were more resistant to osmotic stress than human erythrocytes, but osmotic stress tolerance per se did not confer HlyA resistance. Erythrocytes from T. scripta, which showed higher osmotic resistance than python erythrocytes, were as susceptible to HlyA as human erythrocytes. Therefore, we tested whether python erythrocytes lack the purinergic signalling known to amplify HlyA-induced hemolysis in human erythrocytes. P. regius erythrocytes increased intracellular Ca²⁺ concentration and reduced cell volume when exposed to 3 mM ATP, indicating the presence of a P2X₇-like receptor. In addition, scavenging extracellular ATP or blocking P2 receptors or pannexin channels reduced the HlyA-induced hemolysis. We tested whether the low HlyA sensitivity resulted from low affinity of HlyA to the python erythrocyte membrane. We found comparable incorporation of HlyA into human and python erythrocyte membranes. Taken together, the remarkable HlyA resistance of python erythrocytes was not explained by increased osmotic resistance, lack of purinergic hemolysis amplification, or differences in HlyA affinity.

  4. Safety assessment and detection method of genetically modified Chinese Kale (Brassica oleracea cv. alboglabra ).

    Science.gov (United States)

    Lin, Chih-Hui; Lu, Chien-Te; Lin, Hsin-Tang; Pan, Tzu-Ming

    2009-03-11

    Sporamins are tuberous storage proteins and account for 80% of soluble protein in sweet potato tubers with trypsin-inhibitory activity. The expression of sporamin protein in transgenic Chinese kale (line BoA 3-1) conferred insecticidal activity toward corn earworm [ Helicoverpa armigera (Hubner)] in a previous report. In this study, we present a preliminary safety assessment of transgenic Chinese kale BoA 3-1. Bioinformatic and simulated gastric fluid (SGF) analyses were performed to evaluate the allergenicity of sporamin protein. The substantial equivalence between transgenic Chinese kale and its wild-type host has been demonstrated by the comparison of important constituents. A reliable real-time polymerase chain reaction (PCR) detection method was also developed to control sample quality. Despite the results of most evaluations in this study being negative, the safety of sporamin in transgenic Chinese kale BoA 3-1 was uncluded because of the allergenic risk revealed by bioinformatic analysis.

  5. Computer-based Creativity Enhanced Conceptual Design Model for Non-routine Design of Mechanical Systems

    Institute of Scientific and Technical Information of China (English)

    LI Yutong; WANG Yuxin; DUFFY Alex H B

    2014-01-01

    Computer-based conceptual design for routine design has made great strides, yet non-routine design has not been given due attention, and it is still poorly automated. Considering that the function-behavior-structure(FBS) model is widely used for modeling the conceptual design process, a computer-based creativity enhanced conceptual design model(CECD) for non-routine design of mechanical systems is presented. In the model, the leaf functions in the FBS model are decomposed into and represented with fine-grain basic operation actions(BOA), and the corresponding BOA set in the function domain is then constructed. Choosing building blocks from the database, and expressing their multiple functions with BOAs, the BOA set in the structure domain is formed. Through rule-based dynamic partition of the BOA set in the function domain, many variants of regenerated functional schemes are generated. For enhancing the capability to introduce new design variables into the conceptual design process, and dig out more innovative physical structure schemes, the indirect function-structure matching strategy based on reconstructing the combined structure schemes is adopted. By adjusting the tightness of the partition rules and the granularity of the divided BOA subsets, and making full use of the main function and secondary functions of each basic structure in the process of reconstructing of the physical structures, new design variables and variants are introduced into the physical structure scheme reconstructing process, and a great number of simpler physical structure schemes to accomplish the overall function organically are figured out. The creativity enhanced conceptual design model presented has a dominant capability in introducing new deign variables in function domain and digging out simpler physical structures to accomplish the overall function, therefore it can be utilized to solve non-routine conceptual design problem.

  6. Computer-based creativity enhanced conceptual design model for non-routine design of mechanical systems

    Science.gov (United States)

    Li, Yutong; Wang, Yuxin; Duffy, Alex H. B.

    2014-11-01

    Computer-based conceptual design for routine design has made great strides, yet non-routine design has not been given due attention, and it is still poorly automated. Considering that the function-behavior-structure(FBS) model is widely used for modeling the conceptual design process, a computer-based creativity enhanced conceptual design model(CECD) for non-routine design of mechanical systems is presented. In the model, the leaf functions in the FBS model are decomposed into and represented with fine-grain basic operation actions(BOA), and the corresponding BOA set in the function domain is then constructed. Choosing building blocks from the database, and expressing their multiple functions with BOAs, the BOA set in the structure domain is formed. Through rule-based dynamic partition of the BOA set in the function domain, many variants of regenerated functional schemes are generated. For enhancing the capability to introduce new design variables into the conceptual design process, and dig out more innovative physical structure schemes, the indirect function-structure matching strategy based on reconstructing the combined structure schemes is adopted. By adjusting the tightness of the partition rules and the granularity of the divided BOA subsets, and making full use of the main function and secondary functions of each basic structure in the process of reconstructing of the physical structures, new design variables and variants are introduced into the physical structure scheme reconstructing process, and a great number of simpler physical structure schemes to accomplish the overall function organically are figured out. The creativity enhanced conceptual design model presented has a dominant capability in introducing new deign variables in function domain and digging out simpler physical structures to accomplish the overall function, therefore it can be utilized to solve non-routine conceptual design problem.

  7. Review of multi-dimensional large-scale kinetic simulation and physics validation of ion acceleration in relativistic laser-matter interaction

    International Nuclear Information System (INIS)

    Wu, Hui-Chun; Hegelich, B.M.; Fernandez, J.C.; Shah, R.C.; Palaniyappan, S.; Jung, D.; Yin, L.; Albright, B.J.; Bowers, K.; Kwan, T.J.

    2012-01-01

    Two new experimental technologies enabled realization of Break-out afterburner (BOA) - High quality Trident laser and free-standing C nm-targets. VPIC is an powerful tool for fundamental research of relativistic laser-matter interaction. Predictions from VPIC are validated - Novel BOA and Solitary ion acceleration mechanisms. VPIC is a fully explicit Particle In Cell (PIC) code: models plasma as billions of macro-particles moving on a computational mesh. VPIC particle advance (which typically dominates computation) has been optimized extensively for many different supercomputers. Laser-driven ions lead to realization promising applications - Ion-based fast ignition; active interrogation, hadron therapy.

  8. Stability of the superconductive operating mode in high current-density devices

    International Nuclear Information System (INIS)

    Wipf, S.L.

    1979-01-01

    The superconductive operating mode represents a thermal equilibrium that can tolerate a certain amount of disturbance before it is lost. The basin of attraction (BOA), in many ways equivalent to a potential well, is a measure of the size of disturbance needed to lift the device from the superconductive into a resistive operating mode. The BOA for a simple geometry is calculated and discussed. Experimental results are reported, showing how the concept is used to gain information on the disturbances occurring in a superconducting device

  9. A distinção entre o sentido negativo e positivo da liberdade na Fundamentação da Metafísica dos Costumes

    OpenAIRE

    Hipolito, Marco André de Freitas

    2011-01-01

    O presente trabalho pretende analisar a distinção entre o conceito de liberdade em sentido negativo e o de liberdade em sentido positivo, enfatizando, também, os conceitos que Kant utiliza para fundamentar a moral sob a idéia da liberdade em sentido positivo. No primeiro capítulo analisamos a tese kantiana de que somente mediante uma boa vontade haveria a possibilidade de agir moralmente. A boa vontade é tida por Kant como um princípio do querer, que deve ser determinado por si...

  10. Modulating patterns of two-phase flow with electric fields.

    Science.gov (United States)

    Liu, Dingsheng; Hakimi, Bejan; Volny, Michael; Rolfs, Joelle; Anand, Robbyn K; Turecek, Frantisek; Chiu, Daniel T

    2014-07-01

    This paper describes the use of electro-hydrodynamic actuation to control the transition between three major flow patterns of an aqueous-oil Newtonian flow in a microchannel: droplets, beads-on-a-string (BOAS), and multi-stream laminar flow. We observed interesting transitional flow patterns between droplets and BOAS as the electric field was modulated. The ability to control flow patterns of a two-phase fluid in a microchannel adds to the microfluidic tool box and improves our understanding of this interesting fluid behavior.

  11. Kutenai Indian Subsistence and Settlement Patterns.

    Science.gov (United States)

    1984-09-01

    Turner 1978:180-182) Serviceberries have been "found to contain three times as much iron ..-..... and copper as prunes and raisins" (Driver and...slopes in well-drained soil. Chokecherries The chokecherry (Prunus virginiana , "wild cherry, cherry" UK. aa’kL&mak! [Boas 1918:357], UK. akifilmaka... virginiana , "blue-leaf strawberry" with globular fruit; UK. aaq!iuko’, aa’kQo [Boas 1918:381], UK. akoku [Curtis 1911 7:175]) were gathered 0 and eaten by

  12. Queratocone e lentes de contacto

    OpenAIRE

    Coutinho, I; Ramalho, M; Pedrosa, C; Pina, S; Mota, M; Santos, C; Vendrell, C

    2014-01-01

    Nos doentes com queratocone quando os óculos não possibilitam boa visão, as lentes de contacto são uma boa alternativa terapêutica. Há vários desenhos de lentes de contacto que podem ser utilizados na correção óptica do queratocone e a sua adaptação deve assegurar o menor trauma da córnea e conforto ao doente. Este trabalho pretende fazer fazendo-se breve revisão das lentes de contacto disponíveis no tratamento do queratocone.

  13. Peripheral vascular effects of bretylium tosylate in man.

    Science.gov (United States)

    Blair, D A; Glover, W E; Kidd, B S; Roddie, I C

    1960-09-01

    After intra-arterial infusion of bretylium tosylate (12.5 mg.), the reflex changes in vasoconstrictor tone which normally occur in the forearm with body cooling, positive pressure breathing, the Valsalva manoeuvre and postural change were greatly reduced or abolished. Reflex vasodilatation mediated by cholinergic fibres in response to body heating or to emotional stress was little affected. It was concluded that bretylium can selectively block the activity of sympathetic noradrenergic fibres without causing a similar block of sympathetic cholinergic fibres. As the responses to intravenous or intra-arterial infusions of adrenaline or noradrenaline were not reduced after bretylium, it was concluded that bretylium interferes with the activity of noradrenergic fibres rather than with the activity of the noradrenaline released at the nerve ending. After bretylium infusion, forearm and hand blood flow did not often rise to levels characteristic of full release of vasoconstrictor tone. As infusion of bretylium into a nerve-blocked forearm resulted in a pronounced reduction in flow, it is concluded that bretylium also has a constrictor effect on blood vessels. The state of the vessels following an infusion of bretylium appears to depend on the balance between this constrictor action and the longer-acting sympathetic blocking effect.

  14. Functional analysis of the musculo-skeletal system of the gill apparatus in Heptranchias perlo (Chondrichthyes: Hexanchidae).

    Science.gov (United States)

    Kryukova, Nadezhda V

    2017-08-01

    Musculo-skeletal morphology is an indispensable source for understanding functional adaptations. Analysis of morphology of the branchial apparatus of Hexanchiform sharks can provide insight into aspects of their respiration that are difficult to observe directly. In this study, I compare the structure of the musculo-skeletal system of the gill apparatus of Heptranchias perlo and Squalus acanthias in respect to their adaptation for one of two respiratory mechanisms known in sharks, namely, the active two-pump (oropharyngeal and parabranchial) ventilation and the ram-jet ventilation. In both species, the oropharyngeal pump possesses two sets of muscles, one for compression and the other for expansion. The parabranchial pump only has constrictors. Expansion of this pump occurs only due to passive elastic recoil of the extrabranchial cartilages. In Squalus acanthias the parabranchial chambers are large and equipped by powerful superficial constrictors. These muscles and the outer walls of the parabranchial chambers are much reduced in Heptranchias perlo, and thus it likely cannot use this pump. However, this reduction allows for vertical elongation of outer gill slits which, along with greater number of gill pouches, likely decreases branchial resistance and, at the same time, increases the gill surface area, and can be regarded as an adaptation for ram ventilation at lower speeds. © 2017 Wiley Periodicals, Inc.

  15. Evaluation of noncoronary sources of left ventricular perfusion to intercoronary collateral-dependent myocardium due to chronic major vessel occlusion: absent contribution of luminal and extracardiac channels

    International Nuclear Information System (INIS)

    Crystal, G.J.; Downey, H.F.; Bashour, F.A.

    1981-01-01

    Liminal contribution to perfusion of collateral-dependent left ventricular (LV) myocardium was evaluated in six dogs. A portion of LV free wall was rendered collateral-dependent by gradual occlusion of left circumflex artery with Ameroid constrictor. Eight to 10 weeks after implantation of constrictor, measurements of LV myocardial flow were made by left atrial injections of 9-10 micro radioactive microspheres. To measure total collateral flow, microspheres were injected under control conditions, and to measure luminal contribution to collateral flow, microspheres were injected after ligation of right coronary artery during extracorporeal perfusion of left common coronary artery (LCCA) with microsphere-free arterial blood, and during stoppage of flow through LCCA. Under control conditions, myocardial blood flow in collateral-dependent region, 1.01 +/- 0.31 ml/min/gm, was not significantly different from that in normal region, 1.06 +/- 0.32 ml/min/gm. Flow from luminal collateral vessels was negligible (less than 0.005 ml/min/gm) in both collateral-dependent and normal myocardium, and was not affected by stoppage of flow through LCCA. These results indicate that luminal collateral vessels, as well as collateral vessels originating from other noncoronary sources, do not contribute significantly to perfusion of normal or collateral-dependent LV myocardium

  16. Dysphagia - Results from multivariable predictive modelling on aspiration from a subset of the ARTSCAN trial.

    Science.gov (United States)

    Söderström, Karin; Nilsson, Per; Laurell, Göran; Zackrisson, Björn; Jäghagen, Eva Levring

    2017-02-01

    To establish predictive models for late objective aspiration and late patient-reported choking based on dose-volume parameters and baseline patient and treatment characteristics, for patients with head and neck cancer undergoing definitive radiotherapy (RT). The impact of electively treated volume on late aspiration was also investigated. This prospective cohort is a subsample of 124 survivors from the ARTSCAN study. Late aspiration was identified with videofluoroscopy, at a minimum of 25months after the start of RT. Patient-reported choking was analysed at 12 and 60months post RT using the EORTC Quality of Life Module for Head and Neck Cancer 35. Univariable and multivariable analyses were performed to describe the association between clinical factors and dose-volume descriptors for organs at risk (OARs) and late dysphagia. Aspiration was found in 47% of the eligible patients. Mean dose to the middle pharyngeal constrictor (MPC), neck dissection post RT and age at randomisation in ARTSCAN were associated to late aspiration. Mean dose to the superior pharyngeal constrictor (SPC) and swallowing complaints at baseline were associated to patient reported choking at both time-points. Three separate risk groups for late aspiration, and two risk groups for late patient-reported choking were identified based on number of risk factors. The size of the electively treated volume could be used as a surrogate for individual OARs predicting late aspiration. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  17. Low power arcjet performance

    Science.gov (United States)

    Curran, Francis M.; Sarmiento, Charles J.

    1990-01-01

    An experimental investigation was performed to evaluate arcjet operation at low power. A standard, 1 kW, constricted arcjet was run using nozzles with three different constrictor diameters. Each nozzle was run over a range of current and mass flow rates to explore stability and performance in the low power regime. A standard pulse-width modulated power processor was modified to accommodate the high operating voltages required under certain conditions. Stable, reliable operation at power levels below 0.5 kW was obtained at efficiencies between 30 and 40 percent. The operating range was found to be somewhat dependent on constrictor geometry at low mass flow rates. Quasi-periodic voltage fluctuations were observed at the low power end of the operating envelope. The nozzle insert geometry was found to have little effect on the performance of the device. The observed performance levels show that specific impulse levels above 350 seconds can be obtained at the 0.5 kW power level.

  18. Dysphagia After Chemoradiotherapy for Head-and-Neck Squamous Cell Carcinoma: Dose-Effect Relationships for the Swallowing Structures

    International Nuclear Information System (INIS)

    Dirix, Piet; Abbeel, Sarah; Vanstraelen, Bianca; Hermans, Robert; Nuyts, Sandra

    2009-01-01

    Purpose: To evaluate late dysphagia after chemoradiotherapy for locally advanced head-and-neck squamous cell carcinoma, and to examine its correlation with clinical and dosimetric parameters. Methods and Materials: Consecutive patients, treated with radiotherapy (70-72 Gy) and concomitant chemotherapy (cisplatinum 100 mg/m 2 every 3 weeks) between 2004 and 2007, were examined. Swallowing was evaluated by four quality-of-life questionnaires: EORTC C30 and H and N35, the Performance Status Scale of List, and the MD Anderson Dysphagia Inventory. Clinical and dosimetric parameters were correlated with late dysphagia. Results: A total of 53 disease-free patients were evaluated; mean follow-up was 20.4 months (range, 6-45 months). The volume of the middle pharyngeal constrictor muscle receiving ≥50 Gy (p = 0.04), the mean dose to this structure (p = 0.02) and to the supraglottic larynx (p = 0.04) were significantly associated with late swallowing problems at univariate analysis, along with tumor localization (p = 0.008), T-classification (p = 0.02), and pretreatment swallowing problems (p = 0.01). Only this last factor significantly correlated with late dysphagia at multivariate analysis. Conclusion: These findings motivate further efforts to reduce the dose to the swallowing structures, especially to the pharyngeal constrictor muscles and the larynx. However, clinical parameters are also important and should be included in future prospective trials.

  19. Clinical-dosimetric analysis of measures of dysphagia including gastrostomy-tube dependence among head and neck cancer patients treated definitively by intensity-modulated radiotherapy with concurrent chemotherapy

    International Nuclear Information System (INIS)

    Li, Baoqing; Chen, Allen M; Li, Dan; Lau, Derick H; Farwell, D Gregory; Luu, Quang; Rocke, David M; Newman, Kathleen; Courquin, Jean; Purdy, James A

    2009-01-01

    To investigate the association between dose to various anatomical structures and dysphagia among patients with head and neck cancer treated by definitive intensity-modulated radiotherapy (IMRT) and concurrent chemotherapy. Thirty-nine patients with squamous cancer of the head and neck were treated by definitive concurrent chemotherapy and IMRT to a median dose of 70 Gy (range, 68 to 72). In each patient, a gastrostomy tube (GT) was prophylacticly placed prior to starting treatment. Prolonged GT dependence was defined as exceeding the median GT duration of 192 days. Dysphagia was scored using standardized quality-of-life instruments. Dose-volume histogram (DVH) data incorporating the superior/middle pharyngeal constrictors (SMPC), inferior pharyngeal constrictor (IPC), cricoid pharyngeal inlet (CPI), and cervical esophagus (CE) were analyzed in relation to prolonged GT dependence, dysphagia, and weight loss. At 3 months and 6 months after treatment, 87% and 44% of patients, respectively, were GT dependent. Spearman's ρ analysis identified statistical correlations (p < 0.05) between prolonged GT dependence or high grade dysphagia with IPC V65, IPC V60, IPC Dmean, and CPI Dmax. Logistic regression model showed that IPC V65 > 30%, IPC V60 > 60%, IPC Dmean > 60 Gy, and CPI Dmax > 62 Gy predicted for greater than 50% probability of prolonged GT dependence. Our analysis suggests that adhering to the following parameters may decrease the risk of prolonged GT dependence and dysphagia: IPC V65 < 15%, IPC V60 < 40%, IPC Dmean < 55 Gy, and CPI Dmax < 60 Gy

  20. The use of coronary vasodilators in myocardial imaging with 43K

    International Nuclear Information System (INIS)

    Markov, A.K.; Smith, R.O.; Oglethorpe, N.C.; Lehan, P.H.; Hellems, H.K.

    1980-01-01

    As an alternative procedure to the exercise stress test used in myocardial scanning, vasoactive drugs were employed to elicit deficits in blood flow to myocardial regions supplied by stenotic arteries. The data were collected from 35 dogs, some of which had partial stenosis on either major branch of the left coronary artery, and others which had Ameroid constrictor implants. The effects of lidoflazine, dipyridamole, and nitroglycerin on coronary hemodynamics and myocardial dispersion of 43 K in animals with partial stenosis were evaluated in ten acute experiments. In the pilot studies, four rapid serial rectilinear control scans from 43 K (750 μCi) were reported; dipyridamole, lidoflazine, or nitroglycerin were then administered intravenously. When the selected drug reached a peak vasodilatative effect, a second equal bolus of 43 K was given and four additional scans recorded. The control scans from dogs with partial stenosis or an Ameroid constrictor showed homogeneous distribution of the myocardial 43 K. When drugs were used, the region supplied by compromised circulation became apparent because of lower counts when compared to the normally perfused ones. Coronary vasodilators, as opposed to postexercise in myocardial imaging, have a lesser effect on cardiac dynamics, peripheral hemodynamics, and also double the 43 K uptake in normally perfused myocardium. (orig.) [de