WorldWideScience

Sample records for region line profiles

  1. Line profiles of the two-phase medium broad-line region in active galactic nuclei

    Institute of Scientific and Technical Information of China (English)

    薛随建; 林宣滨; 程福臻; John Kwan

    1996-01-01

    In the framework of BLR in AGNs, i.e. large number of small, cold and dense emission-line clouds immerging in an intercloud hot medium, a delicate radiation model for a typical emission cloud is established, in which the backside photoionization of the cloud against the central continuum source by the scattered diffuse continuum in the hot medium is considered. Under the assumption of the radial kinematics of the BLR clouds, the line profiles for the two important UV emission-lines, Lya and CIV/11549 are computed; and based on these calculations, various physical factors that affect the properties of the emission-line profiles are discussed. It is concluded that: (i) when the BLR clouds is inflow, there exists a confining hot medium with density around 2 x 105 cm-3. In this case, theoretical line profiles agree well with the observational; (ii) both symmetric Lya and nearly symmetric CIV line profiles show blue velocity shifts, the quantities of which are sensitive to the cutoff of the outer radius of t

  2. Line profiles of water for the photon dominated region and embedded sources in the S140 region

    CERN Document Server

    Poelman, D R

    2006-01-01

    A radiative transfer method for the treatment of molecular lines is presented. We apply this method to previous SWAS and ISO observations of water vapor in the source S140 in order to make models to plan for, and to interpret, HIFI data. Level populations are calculated with the use of a three-dimensional (multi-zone) escape probability method and with a long characteristic code that uses Monte Carlo techniques with fixed directions. Homogeneous and inhomogeneous models are used to compute the differences between water line profiles across the S140 region. We find that when an outflow or infall velocity field with a gradient of a few kms^{-1} is adopted, line profiles with a FWHM of 6 kms^{-1} are found, in agreement with observations. Inhomogeneous models are favoured to produce a single-peaked line profile. When zooming in on smaller regions within the PDR, the shapes of the line profiles start to differ due to the different temperature and density distributions there. The embedded sources are traced by hig...

  3. Molecular absorption in transition region spectral lines

    CERN Document Server

    Schmit, Donald; Ayres, Thomas; Peter, Hardi; Curdt, Werner; Jaeggli, Sarah

    2014-01-01

    Aims: We present observations from the Interface Region Imaging Spectrograph (IRIS) of absorption features from a multitude of cool atomic and molecular lines within the profiles of Si IV transition region lines. Many of these spectral lines have not previously been detected in solar spectra. Methods: We examined spectra taken from deep exposures of plage on 12 October 2013. We observed unique absorption spectra over a magnetic element which is bright in transition region line emission and the ultraviolet continuum. We compared the absorption spectra with emission spectra that is likely related to fluorescence. Results: The absorption features require a population of sub-5000 K plasma to exist above the transition region. This peculiar stratification is an extreme deviation from the canonical structure of the chromosphere-corona boundary . The cool material is not associated with a filament or discernible coronal rain. This suggests that molecules may form in the upper solar atmosphere on small spatial scales...

  4. Predicted profiles of ultraviolet interstellar absorption lines

    Energy Technology Data Exchange (ETDEWEB)

    Welty, D.E.; Hobbs, L.M.; York, D.G. (Chicago, University, IL (USA))

    1991-02-01

    In this paper, values of the column density, line width parameter, and velocity are determined for as many components derived from optical interstellar absorption-line profiles of Na I and K I as needed to reproduce the observed high-resolution optical profiles of the D lines of Na I toward eight lightly reddened stars and of the 7698 A line of K I toward six moderately reddened stars. The derived component structures are then used to predict UV absorption-line profiles due to C I, Mg I, S I, Si I, and Fe I along the same lines of sight. Comparison of the predicted profiles with existing lower resolution line profiles and equivalent width data suggests that this simple scaling procedure can in many cases fairly reliably predict the UV profiles from the observed optical ones. 64 refs.

  5. On the Intermediate Line Region in AGNs

    Directory of Open Access Journals (Sweden)

    Tek P. Adhikari

    2017-09-01

    Full Text Available In this paper we explore the intermediate line region (ILR by using the photoionisation simulations of the gas clouds present at different radial distances from the center, corresponding to the locations from BLR out to NLR in four types of AGNs. We let for the presence of dust whenever conditions allow for dust existence. All spectral shapes are taken from the recent multi-wavelength campaigns. The cloud density decreases with distance as a power law. We found that the slope of the power law density profile does not affect the line emissivity radial profiles of major emission lines: Hβ, He II, Mg II, C III, and O III. When the density of the cloud at the sublimation radius is as high as 1011.5 cm−3, the ILR should clearly be seen in the observations independently of the shape of the illuminating radiation. Moreover, our result is valid for low ionization nuclear emission regions of active galaxies.

  6. Giant Broad Line Regions in Dwarf Seyferts

    Indian Academy of Sciences (India)

    Nick Devereux

    2015-12-01

    High angular resolution spectroscopy obtained with the Hubble Space Telescope (HST) has revealed a remarkable population of galaxies hosting dwarf Seyfert nuclei with an unusually large broad-line region (BLR). These objects are remarkable for two reasons. Firstly, the size of the BLR can, in some cases, rival those seen in the most luminous quasars. Secondly, the size of the BLR is not correlated with the central continuum luminosity, an observation that distinguishes them from their reverberating counterparts. Collectively, these early results suggest that non-reverberating dwarf Seyferts are a heterogeneous group, and not simply scaled versions of each other. Careful inspection reveals broad H Balmer emission lines with single peaks, double peaks, and a combination of the two, suggesting that the broad emission lines are produced in kinematically distinct regions centered on the black hole (BH). Because the gravitational field strength is already known for these objects, by virtue of knowing their BH mass, the relationship between velocity and radius may be established, given a kinematic model for the BLR gas. In this way, one can determine the inner and outer radii of the BLRs by modeling the shape of their broad emission line profiles. In the present contribution, high quality spectra obtained with the Space Telescope Imaging Spectrograph (STIS) are used to constrain the size of the BLR in the dwarf Seyfert nuclei of M81, NGC 3998, NGC 4203, NGC 3227, NGC 4051 and NGC 3516.

  7. PROFIT: a new alternative for emission-line PROfile FITting

    CERN Document Server

    Riffel, Rogemar A

    2010-01-01

    I briefly describe a simple routine for emission-line profiles fitting by Gaussian curves or Gauss-Hermite series. The PROFIT (line-PROfile FITting) routine represent a new alternative for use in fits data cubes, as those from Integral Field Spectroscopy or Fabry-Perot Interferometry, and may be useful to better study the emission-line flux distributions and gas kinematics in distinct astrophysical objects, such as the central regions of galaxies and star forming regions. The PROFIT routine is written in IDL language and is available at http://www.ufsm.br/rogemar/software.html. The PROFIT routine was used to fit the [Fe II]1.257um emission-line profiles for about 1800 spectra of the inner 350 pc of the Seyfert galaxy Mrk1066 obtained with Gemini NIFS and shows that the line profiles are better reproduced by Gauss-Hermite series than by the commonly used Gaussian curves. The two-dimensional map of the h_3 Gauss-Hermite moment shows its highest absolute values in regions close to the edge of the radio structure...

  8. Iron Line Profiles in Strong Gravity

    CERN Document Server

    Beckwith, K; Beckwith, Kris; Done, Chris

    2004-01-01

    We describe a new code which can accurately calculate the relativistic effects which distort the emission from an accretion disc around a black hole. We compare our results for a disk from 6-20r_g in both Schwarzchild and extreme Kerr spacetimes with the two line profile codes which are on general release in the XSPEC spectral fitting package. These are generally accurate at the 10-20% level for this range of radii, but have some drawbacks in terms of assumptions and/or resolution. In particular we show that the assumed form of the angular emissivity law (limb darkening or brightening) can make significant changes to the derived line profile. Lightbending effects are never negligible at these radii, so the observed line is produced from a range of different emitted angles, and this can affect the derived radial emissivity law. The line profile is not simply determined by the well defined (but numerically difficult) physical effects of strong gravity, but is also dependent on the poorly known astrophysics of t...

  9. Modelling of asymmetric nebulae. II. Line profiles

    CERN Document Server

    Morisset, C

    2006-01-01

    We present a tool, VELNEB_3D, which can be applied to the results of 3D photoionization codes to generate emission line profiles, position-velocity maps and 3D maps in any emission line by assuming an arbitrary velocity field. We give a few examples, based on our pseudo-3D photoionization code NEBU_3D (Morisset, Stasinska and Pena, 2005) which show the potentiality and usefulness of our tool. One example shows how complex line profiles can be obtained even with a simple expansion law if the nebula is bipolar and the slit slightly off-center. Another example shows different ways to produce line profiles that could be attributed to a turbulent velocity field while there is no turbulence in the model. A third example shows how, in certain circumstances, it is possible to discriminate between two very different geometrical structures -- here a face-on blister and its ``spherical impostor'' -- when using appropriate high resolution spectra. Finally, we show how our tool is able to generate 3D maps, similar to the ...

  10. Abundance sensitive points of line profiles in the stellar spectra

    CERN Document Server

    Sheminova, V A

    2014-01-01

    Many abundance studies are based on spectrum synthesis and $\\chi$-squared differences between the synthesized and an observed spectrum. Much of the spectra so compared depend only weakly on the elemental abundances. Logarithmic plots of line depths rather than relative flux make this more apparent. We present simulations that illustrate a simple method for finding regions of the spectrum most sensitive to abundance, and also some caveats for using such information. As expected, we find that weak features are the most sensitive. Equivalent widths of weak lines are ideal features, because of their sensitivity to abundances, and insensitivity to factors that broaden the line profiles. The wings of strong lines can also be useful, but it is essential that the broadening mechanisms be accurately known. The very weakest features, though sensitive to abundance, should be avoided or used with great caution because of uncertainty of continuum placement as well as numerical uncertainties associated with the subtraction...

  11. The Narrow Line Region of Ark 564

    CERN Document Server

    Contini, M; Viegas, S M M; Contini, Marcella; Rodriguez-Ardila, Alberto; Viegas, Sueli

    2003-01-01

    The continuum and emission-line spectrum of the narrow-line Seyfert 1 galaxy Ark 564 is used to investigate, for the first time, the physical conditions and structure of its narrow line region (NLR). For this purpose, composite models, accounting for the coupled effect of photoionization and shocks, are employed. The emission-line spectrum of Ark 564, which ranges from the ultraviolet to the near-infrared, shows a rich forbidden line spectrum. Strong emphasis is given to the study of the coronal line region. The diversity of physical conditions deduced from the observations requires multi-cloud models to reproduce the observed lines and continuum. We find that a combination of high velocity (Vs = 1500 km/s) shock-dominated clouds as well as low velocity (Vs = 150 km/s) radiation-dominated clouds explains the coronal lines, while the optical low-ionization lines are mainly explained by shock-dominated clouds. The results for Ark 564 are compared with those obtained for other Seyfert galaxies previously analyze...

  12. Helium line formation and abundance in a solar active region

    CERN Document Server

    Mauas, P J D; Falchi, A; Falciani, R; Teriaca, L N; Cauzzi, G

    2004-01-01

    An observing campaign (SOHO JOP 139), coordinated between ground based and SOHO instruments, has been planned to obtain simultaneous spectroheliograms of the same active region in several spectral lines. The chromospheric lines CaII K, Halpha and Na D as well as HeI 10830, 5876, 584 and HeII 304 AA lines have been observed.These simultaneous observations allow us to build semi-empirical models of the chromosphere and low transition region of an active region, taking into account the estimated total number of photoionizing photons impinging on the target active region and their spectral distribution. We obtained a model that matches very well all the observed line profiles, using a standard value for the He abundance ([He]=0.1) and a modified distribution of microturbulence. For this model we study the influence of the coronal radiation on the computed helium lines. We find that, even in an active region, the incident coronal radiation has a limited effect on the UV He lines, while it results of fundamental im...

  13. Profiles of Strong Permitted Lines in Classical T Tauri Stars

    CERN Document Server

    Alencar, S; Alencar, Silvia; Basri, Gibor

    2000-01-01

    We present a spectral analysis of 30 T Tauri stars observed with the Hamilton echelle spectrograph over more than a decade. One goal is to test magnetospheric accretion model predictions. Observational evidence previously published supporting the model, such as emission line asymmetry and a high frequency of redshifted absorption components, are considered. We also discuss the relation between different line forming regions and search for good accretion rate indicators. In this work we confirm several important points of the models, such as the correlation between accretion and outflow, broad emission components that are mostly central or slightly blueshifted and only the occasional presence of redshifted absorption. We also show, however, that the broad emission components supposedly formed in the magnetospheric accretion flow only partially support the models. Unlike the predictions, they are sometimes redshifted, and are mostly found to be symmetric. The published theoretical profiles do not have a strong ...

  14. Giant Broad Line Regions in Dwarf Seyferts

    CERN Document Server

    Devereux, Nick

    2015-01-01

    High angular resolution spectroscopy obtained with the Hubble Space Telescope (HST) has revealed a remarkable population of galaxies hosting dwarf Seyfert nuclei with an unusually large broad-line region (BLR). These objects are remarkable for two reasons. Firstly, the size of the BLR can, in some cases, rival those seen in the most luminous quasars. Secondly, the size of the BLR is not correlated with the central continuum luminosity, an observation that distinguishes them from their reverberating counterparts. Collectively, these early results suggest that non-reverberating dwarf Seyferts are a heterogeneous group and not simply scaled versions of each other. Careful inspection reveals broad H Balmer emission lines with single peaks, double peaks, and a combination of the two, suggesting that the broad emission lines are produced in kinematically distinct regions centered on the black hole (BH). Because the gravitational field strength is already known for these objects, by virtue of knowing their BH mass, ...

  15. Speed-dependent spectral line profile including line narrowing and mixing

    Science.gov (United States)

    Kochanov, Victor P.

    2016-07-01

    A line profile model was developed that accounts for all essential underlying physical mechanisms. The model is based on the quantum-mechanical collision integral kernel calculated for intermolecular interaction potentials ∝r-n with n=3…6 where r is the distance between colliding molecules. It was shown that collisions of molecules with scattering on classical small angles flatten the line profile. The relative flattening reaches 10% for n=3 and has a smaller value, ~2%, for n=6 in conditions of inhomogeneous line broadening. An algebraic expression for the line profile was obtained, which allows processing recorded spectra with preliminary estimation and constraint of some of the profile's parameters.

  16. Radio Recombination Lines in Galactic HII Regions

    CERN Document Server

    Quireza, C; Bania, T M; Rood, R T; Balser, Dana S.; Quireza, Cintia; Rood, Robert T.

    2006-01-01

    We report radio recombination line (RRL) and continuum observations of a sample of 106 Galactic HII regions made with the NRAO 140 Foot radio telescope in Green Bank, WV. We believe this to be the most sensitive RRL survey ever made for a sample this large. Most of our source integration times range between 6 and 90 hours which yield typical r.m.s. noise levels of 1.0--3.5 milliKelvins. Our data result from two different experiments performed, calibrated, and analyzed in similar ways. A CII survey was made at 3.5 cm wavelength to obtain accurate measurements of carbon radio recombination lines. When combined with atomic (CI) and molecular (CO) data, these measurements will constrain the composition, structure, kinematics, and physical properties of the photodissociation regions that lie on the edges of HII regions. A second survey was made at 3.5 cm wavelength to determine the abundance of 3He in the interstellar medium of the Milky Way. Together with measurements of the 3He+ hyperfine line we get high precis...

  17. Simulation study for measurement of horizontal wind profiles in the polar stratosphere and mesosphere using ground-based observations of ozone and carbon monoxide lines in the 230-250 GHz region

    Science.gov (United States)

    Newnham, David A.; Ford, George P.; Moffat-Griffin, Tracy; Pumphrey, Hugh C.

    2016-07-01

    Meteorological and atmospheric models are being extended up to 80 km altitude but there are very few observing techniques that can measure stratospheric-mesospheric winds at altitudes between 20 and 80 km to verify model datasets. Here we demonstrate the feasibility of horizontal wind profile measurements using ground-based passive millimetre-wave spectroradiometric observations of ozone lines centred at 231.28, 249.79, and 249.96 GHz. Vertical profiles of horizontal winds are retrieved from forward and inverse modelling simulations of the line-of-sight Doppler-shifted atmospheric emission lines above Halley station (75°37' S, 26°14' W), Antarctica. For a radiometer with a system temperature of 1400 K and 30 kHz spectral resolution observing the ozone 231.28 GHz line we estimate that 12 h zonal and meridional wind profiles could be determined over the altitude range 25-74 km in winter, and 28-66 km in summer. Height-dependent measurement uncertainties are in the range 3-8 m s-1 and vertical resolution ˜ 8-16 km. Under optimum observing conditions at Halley a temporal resolution of 1.5 h for measuring either zonal or meridional winds is possible, reducing to 0.5 h for a radiometer with a 700 K system temperature. Combining observations of the 231.28 GHz ozone line and the 230.54 GHz carbon monoxide line gives additional altitude coverage at 85 ± 12 km. The effects of clear-sky seasonal mean winter/summer conditions, zenith angle of the received atmospheric emission, and spectrometer frequency resolution on the altitude coverage, measurement uncertainty, and height and time resolution of the retrieved wind profiles have been determined.

  18. Interplanetary Lyman $\\alpha$ line profiles: variations with solar activity cycle

    CERN Document Server

    Quemerais, E; Bertaux, J L; Koutroumpa, D; Clarke, J; Kyrola, E; Schmidt, W; Qu\\'emerais, Eric; Lallement, Rosine; Bertaux, Jean-Loup; Koutroumpa, Dimitra; Clarke, John; Kyrola, Erkki; Schmidt, Walter

    2006-01-01

    Interplanetary Lyman alpha line profiles are derived from the SWAN H cell data measurements. The measurements cover a 6-year period from solar minimum (1996) to after the solar maximum of 2001. This allows us to study the variations of the line profiles with solar activity. These line profiles were used to derive line shifts and line widths in the interplanetary medium for various angles of the LOS with the interstellar flow direction. The SWAN data results were then compared to an interplanetary background upwind spectrum obtained by STIS/HST in March 2001. We find that the LOS upwind velocity associated with the mean line shift of the IP \\lya line varies from 25.7 km/s to 21.4 km/s from solar minimum to solar maximum. Most of this change is linked with variations in the radiation pressure. LOS kinetic temperatures derived from IP line widths do not vary monotonically with the upwind angle of the LOS. This is not compatible with calculations of IP line profiles based on hot model distributions of interplanet...

  19. A catalogue of Paschen-line profiles in standard stars

    CERN Document Server

    Huang, Wenjin; Stone, Myra; 10.1051/0004-6361/201219804

    2012-01-01

    We have assembled an atlas of line profiles of the Paschen Delta line at 10,049 angstroms for the use of stellar modelling. For a few stars we have substituted the Paschen Gamma line at 10,938 angstroms because the Paschen Delta line blends with other features. Most of the targets are standard stars of spectral types from B to M. A few metal-poor stars have been included. For many of the stars we have also observed the Hydrogen Alpha line so as to compare the profiles of lines originating from the meta-stable n=2 level with lines originating from the n=3 level. The greatest difference in line profile is found for high luminosity and cool stars where the departures from LTE in the population of the n=2 level is expected to be the greatest. For a few stars, sample line profiles have been calculated in the LTE approximation to demonstrate the usefulness of the tabulated and displayed catalogue.

  20. Narrow line Seyfert 1 galaxies: where are the broad line regions?

    Science.gov (United States)

    Mao, Weiming; Hu, Chen; Wang, Jianmin; Bian, Weihao; Zhang, Shu; Zhao, Gang

    2010-12-01

    A sample consisting of 211 narrow line Seyfert 1 galaxies (NLS1s) with high quality spectra from the Sloan Digital Sky Survey (SDSS) is selected to explore where broad line regions are in these objects. We find that the H β profile can be fitted well by three (narrow, intermediate and broad) Gaussian components, and the FWHM ratios of the broad to the intermediate components hold a constant of 3.0 roughly for the entire sample. If the broad components originate from the region scaled by the well-determined H β reverberation mapping relation, we find that the intermediate components originate from the inner edge of the torus, which is scaled by dust K-band reverberation. We find that the IC and the BC are strongly linked dynamically, but the relation of their covering factors is much more relaxed, implying that both regions are clumpy.

  1. Narrow line Seyfert 1 galaxies: where are the broad line regions?

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    A sample consisting of 211 narrow line Seyfert 1 galaxies (NLS1s) with high quality spectra from the Sloan Digital Sky Survey (SDSS) is selected to explore where broad line regions are in these objects. We find that the Hβ profile can be fitted well by three (narrow, intermediate and broad) Gaussian components, and the FWHM ratios of the broad to the intermediate components hold a constant of 3.0 roughly for the entire sample. If the broad components originate from the region scaled by the well-determined Hβ reverberation mapping relation, we find that the intermediate components originate from the inner edge of the torus, which is scaled by dust K-band reverberation. We find that the IC and the BC are strongly linked dynamically, but the relation of their covering factors is much more relaxed, implying that both regions are clumpy.

  2. Photoionisation modelling of the broad line region

    Science.gov (United States)

    King, Anthea

    2016-08-01

    Two of the most fundamental questions regarding the broad line region (BLR) are "what is its structure?" and "how is it moving?" Baldwin et al. (1995) showed that by summing over an ensemble of clouds at differing densities and distances from the ionising source we can easily and naturally produce a spectrum similar to what is observed for AGN. This approach is called the `locally optimally emitting clouds' (LOC) model. This approach can also explain the well-observed stratification of emission lines in the BLR (e.g. Clavel et al. 1991, Peterson et al. 1991, Kollatschny et al. 2001) and `breathing' of BLR with changes in the continuum luminosity (Netzer & Mor 1990, Peterson et al. 2014) and is therefore a generally accepted model of the BLR. However, LOC predictions require some assumptions to be made about the distribution of the clouds within the BLR. By comparing photoionization predictions, for a distribution of cloud properties, with observed spectra we can infer something about the structure of the BLR and distribution of clouds. I use existing reverberation mapping data to constrain the structure of the BLR by observing how individual line strengths and ratios of different lines change in high and low luminosity states. I will present my initial constraints and discuss the challenges associated with the method.

  3. Line Profile Measurements of the Lunar Exospheric Sodium

    Science.gov (United States)

    Oliversen, Ronald J.; Mierkiewicz, Edwin J.; Line, Michael R.; Roesler, Fred L.; Lupie, Olivia L.

    2012-01-01

    We report ongoing results of a program to measure the lunar sodium exospheric line profile from near the lunar limb out to two lunar radii (approx 3500 km). These observations are conducted from the National Solar Observatory McMath-Pierce telescope using a dual-etalon Fabry-Perot spectrometer with a resolving power of 180,600 (1.7 km/s) to measure line widths and velocity shifts of the Na D2 (5889 950 A) emission line in equatorial and polar regions at different lunar phases. The typical field of view (FOV) is 3 arcmin (approx 360 km) with an occasional smaller 1 arcmin FOV used right at the limb edge. The first data were obtained from full Moon to 3 days following full Moon (waning phase) in March 2009 as part of a demonstration run aimed at establishing techniques for a thorough study of temperatures and velocity variations in the lunar sodium exosphere. These data indicate velocity displacements from different locations off the lunar limb range between 150 and 600 m/s from the lunar rest velocity with a precision of +/- 20 to +/- 50 m/s depending on brightness. The measured Doppler line widths for observations within 10.5 arcmin of the east and south lunar limbs for observations between 5 deg and 40 deg lunar phase imply temperatures ranging decreasing from 3250 +/- 260K to 1175 +/- 150K. Additional data is now being collected on a quarterly basis since March 2011 and preliminary results will be reported.

  4. Explaining the unusual line profiles of SN 2006gy

    Science.gov (United States)

    Chugai, Nikolai N.

    2017-02-01

    This paper explores the origin of the enigmatic line profiles of the extremely luminous Type IIn supernova, SN 2006gy, on day 96. Among the conceivable possibilities, the most preferred is the model that suggests there are holes in the optically thick cool dense shell (CDS). The line radiation emitted at the inner side of the opaque CDS escapes through the holes, thus producing an unusual line profile with the emission shifted redward. The holes could emerge as a result of the vigorous Rayleigh-Taylor instability, leading to the CDS fragmentation. The model light curve with the CDS fragmentation is shown to be consistent with the SN 2006gy bolometric light curve.

  5. Explaining unusual line profiles of SN 2006gy

    CERN Document Server

    Chugai, Nikolai

    2016-01-01

    Origin of enigmatic line profiles of extremely luminous type IIn supernova SN~2006gy on day 96 is explored. Among conceivable possibilities the most preferred is the model that suggests holes in the optically thick cool dense shell (CDS). The line radiation emitted at the inner side of the opaque CDS escapes through the holes thus producing unusual line profile with the emission shifted redward. The holes could emerge as a result of a vigorous Rayleigh-Taylor instability leading to the CDS fragmentation. The model light curve with the CDS fragmentation is shown to be consistent with the SN~2006gy bolometric light curve.

  6. The effects of black hole rotation on line profiles from accretion discs

    Energy Technology Data Exchange (ETDEWEB)

    Kojima, Yasufumi (Tokyo Metropolitan Univ. (Japan). Dept. of Physics)

    1991-06-01

    The fluorescent line emitted from an accretion disc around a rotating black hole is examined. The line profiles for various models with inclination angle, Kerr parameter and disc parameters are given. If the emitting region is highly localized to the inner part, r<20 GM/c{sup 2}, the difference due to the black hole rotation appears in the line profiles. Otherwise, the difference is hidden due to photons emitted from larger radii, where the propagation of the radiation and the disc structure are almost independent of the Kerr parameter. (author).

  7. Dislocation Effects on the Diffraction Line Profiles from Nanocrystalline Domains

    Science.gov (United States)

    Leonardi, Alberto; Scardi, Paolo

    2016-12-01

    A Pd nano-polycrystalline microstructure was simulated by molecular dynamics, including edge or screw dislocations in one of the 50 grains, so as to produce a realistic model of nanocrystalline domain with line defect. The same crystalline domain was also studied, with or without line defects, as a free-standing, isolated nanocrystal. Atomic coordinates of the selected domain were used to generate powder patterns by means of the Debye scattering equation, and these patterns were used as "experimental" data to test existing methods of line profile analysis in controlled condition, i.e., with known type and density of defects. Results show that the Krivolgaz-Wilkens theory of dislocation line broadening qualitatively agrees with the MD model, but errors can be larger than 50 pct. A critical issue arises from the instability of the Krivolgaz-Wilkens model when all line profile parameters are simultaneously refined: reasonable results can be obtained by fixing or restricting some parameters.

  8. Theory of satellite structures on spectral-line profiles.

    Science.gov (United States)

    Atakan, A. K.; Jacobson, H. C.

    1973-01-01

    A systematic comparison with experiment of various explanations for the problem of satellite-band formation on spectral-line profiles was initiated. The experiments were performed under a variety of conditions in an effort to construct a consistent model of entire line shapes. A composite theory is detailed which is the result of the insights of many individuals. The calculations indicate that the main features of the problem, the line, the high-intensity red satellites, and the blue satellite can be described simultaneously. The results also indicate that widely different potentials can lead to very similar line profiles. Ancillary conclusions are presented concerning the role of Lennard-Jones potentials in line-shape calculations.

  9. Line Profile Asymmetries and the Chromospheric Flare Velocity Field

    Science.gov (United States)

    Kuridze, D.; Mathioudakis, M.; Simões, P. J. A.; Rouppe van der Voort, L.; Carlsson, M.; Jafarzadeh, S.; Allred, J. C.; Kowalski, A. F.; Kennedy, M.; Fletcher, L.; Graham, D.; Keenan, F. P.

    2015-11-01

    The asymmetries observed in the line profiles of solar flares can provide important diagnostics of the properties and dynamics of the flaring atmosphere. In this paper the evolution of the Hα and Ca ii λ8542 lines are studied using high spatial, temporal, and spectral resolution ground-based observations of an M1.1 flare obtained with the Swedish 1 m Solar Telescope. The temporal evolution of the Hα line profiles from the flare kernel shows excess emission in the red wing (red asymmetry) before flare maximum and excess in the blue wing (blue asymmetry) after maximum. However, the Ca ii λ8542 line does not follow the same pattern, showing only a weak red asymmetry during the flare. RADYN simulations are used to synthesize spectral line profiles for the flaring atmosphere, and good agreement is found with the observations. We show that the red asymmetry observed in Hα is not necessarily associated with plasma downflows, and the blue asymmetry may not be related to plasma upflows. Indeed, we conclude that the steep velocity gradients in the flaring chromosphere modify the wavelength of the central reversal in the Hα line profile. The shift in the wavelength of maximum opacity to shorter and longer wavelengths generates the red and blue asymmetries, respectively.

  10. Detection of Voigt Spectral Line Profiles of Hydrogen Radio Recombination Lines toward Sagittarius B2(N)

    CERN Document Server

    von Prochazka, Azrael A; Balser, Dana S; Ryans, Robert S I; Marshall, Adele H; Schwab, Fredric R; Hollis, Jan M; Jewell, Philip R; Lovas, Frank J

    2010-01-01

    We report the detection of Voigt spectral line profiles of radio recombination lines (RRLs) toward Sagittarius B2(N) with the 100-m Green Bank Telescope (GBT). At radio wavelengths, astronomical spectra are highly populated with RRLs, which serve as ideal probes of the physical conditions in molecular cloud complexes. An analysis of the Hn(alpha) lines presented herein shows that RRLs of higher principal quantum number (n>90) are generally divergent from their expected Gaussian profiles and, moreover, are well described by their respective Voigt profiles. This is in agreement with the theory that spectral lines experience pressure broadening as a result of electron collisions at lower radio frequencies. Given the inherent technical difficulties regarding the detection and profiling of true RRL wing spans and shapes, it is crucial that the observing instrumentation produce flat baselines as well as high sensitivity, high resolution data. The GBT has demonstrated its capabilities regarding all of these aspects,...

  11. Radial dependence of line profile variability in seven O9--B0.5 stars

    CERN Document Server

    Martins, F; Hillier, D J; Donati, J -F; Bouret, J -C

    2014-01-01

    Massive stars show a variety of spectral variability: presence of discrete absorption components in UV P-Cygni profiles, optical line profile variability, X-ray variability, radial velocity modulations. Our goal is to study the spectral variability of single OB stars to better understand the relation between photospheric and wind variability. For that, we rely on high spectral resolution, high signal-to-noise ratio optical spectra collected with the spectrograph NARVAL on the Telescope Bernard Lyot at Pic du Midi. We investigate the variability of twelve spectral lines by means of the Temporal Variance Spectrum (TVS). The selected lines probe the radial structure of the atmosphere, from the photosphere to the outer wind. We also perform a spectroscopic analysis with atmosphere models to derive the stellar and wind properties, and to constrain the formation region of the selected lines. We show that variability is observed in the wind lines of all bright giants and supergiants, on a daily timescale. Lines form...

  12. Magnetohydrodynamic stability of broad line region clouds

    CERN Document Server

    Krause, Martin; Burkert, Andreas

    2012-01-01

    Hydrodynamic stability has been a longstanding issue for the cloud model of the broad line region in active galactic nuclei. We argue that the clouds may be gravitationally bound to the supermassive black hole. If true, stabilisation by thermal pressure alone becomes even more difficult. We further argue that if magnetic fields should be present in such clouds at a level that could affect the stability properties, they need to be strong enough to compete with the radiation pressure on the cloud. This would imply magnetic field values of a few Gauss for a sample of Active Galactic Nuclei we draw from the literature. We then investigate the effect of several magnetic configurations on cloud stability in axi-symmetric magnetohydrodynamic simulations. For a purely azimuthal magnetic field which provides the dominant pressure support, the cloud first gets compressed by the opposing radiative and gravitational forces. The pressure inside the cloud then increases, and it expands vertically. Kelvin-Helmholtz and colu...

  13. Research Into a Neon Spectral Line Profile of Dusty Plasma

    CERN Document Server

    Pikalev, Aleksandr

    2014-01-01

    Ordered dusty structures influence plasma conditions. This influence can be revealed, when plasma spectral characteristics change, as dusty particles are injected. For example, a variation in the atomic temperature leads to a variation in the profiles of spectral lines. We studied the profile of a 585 nm neon spectral line in the dusty structures. The structures levitated in a positive column of a glow discharge at a pressure of 50-150 Pa and with a current of 1-9 mA. We scanned the profile with the use of a Fabry-Perot interferometer, by changing the air pressure between the interferometer mirrors. To process the data, a special algorithm was developed. The algorithm is resistant to a noise and a scanning speed instability. We have found an upper bound of the impact of dusty structures on the profile width. The appearance of macroparticles changes the atomic plasma temperature less than by 10 K.

  14. An atlas of synthetic line profiles of planetary nebulae

    CERN Document Server

    Morisset, C

    2008-01-01

    We have constructed a grid of photoionization models of spherical, elliptical and bipolar planetary nebulae. Assuming different velocity fields, we have computed line profiles corresponding to different orientations, slit sizes and positions. The atlas is meant both for didactic purposes and for the interpretation of data on real nebulae. As an application, we have shown that line profiles are often degenerate, and that recovering the geometry and velocity field from observations requires lines from ions with different masses and different ionization potentials. We have also shown that the empirical way to measure mass-weighted expansion velocities from observed line widths is reasonably accurate if considering the HWHM. For distant nebulae, entirely covered by the slit, the unknown geometry and orientation do not alter the measured velocities statistically. The atlas is freely accessible from internet. The Cloudy_3D suite and the associated VISNEB tool are available on request.

  15. Simulations of Line Profile Structure in Shell Galaxies

    CERN Document Server

    Jilkova, L; Krizek, M; Ebrova, I; Stoklasova, I; Bartakova, T; Bartoskova, K

    2009-01-01

    In the context of exploring mass distributions of dark matter haloes in giant ellipticals, we extend the analysis carried out Merrifield and Kuijken (1998) for stellar line profiles of shells created in nearly radial mergers of galaxies. We show that line-of-sight velocity distributions are more complex than previously predicted. We simulate shell formation and analyze the detectability of spectroscopic signatures of shells after convolution with spectral PSFs.

  16. Sub-megabase resolution tiling (SMRT array-based comparative genomic hybridization profiling reveals novel gains and losses of chromosomal regions in Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma cell lines

    Directory of Open Access Journals (Sweden)

    Lam Wan L

    2008-01-01

    Full Text Available Abstract Background Hodgkin lymphoma (HL and Anaplastic Large Cell Lymphoma (ALCL, are forms of malignant lymphoma defined by unique morphologic, immunophenotypic, genotypic, and clinical characteristics, but both overexpress CD30. We used sub-megabase resolution tiling (SMRT array-based comparative genomic hybridization to screen HL-derived cell lines (KMH2 and L428 and ALCL cell lines (DEL and SR-786 in order to identify disease-associated gene copy number gains and losses. Results Significant copy number gains and losses were observed on several chromosomes in all four cell lines. Assessment of copy number alterations with 26,819 DNA segments identified an average of 20 genetic alterations. Of the recurrent minimally altered regions identified, 11 (55% were within previously published regions of chromosomal alterations in HL and ALCL cell lines while 9 (45% were novel alterations not previously reported. HL cell lines L428 and KMH2 shared gains in chromosome cytobands 2q23.1-q24.2, 7q32.2-q36.3, 9p21.3-p13.3, 12q13.13-q14.1, and losses in 13q12.13-q12.3, and 18q21.32-q23. ALCL cell lines SR-786 and DEL, showed gains in cytobands 5p15.32-p14.3, 20p12.3-q13.11, and 20q13.2-q13.32. Both pairs of HL and ALCL cell lines showed losses in 18q21.32-18q23. Conclusion This study is considered to be the first one describing HL and ALCL cell line genomes at sub-megabase resolution. This high-resolution analysis allowed us to propose novel candidate target genes that could potentially contribute to the pathogenesis of HL and ALCL. FISH was used to confirm the amplification of all three isoforms of the trypsin gene (PRSS1/PRSS2/PRSS3 in KMH2 and L428 (HL and DEL (ALCL cell lines. These are novel findings that have not been previously reported in the lymphoma literature, and opens up an entirely new area of research that has not been previously associated with lymphoma biology. The findings raise interesting possibilities about the role of signaling

  17. Tennessee Valley Region: a year 2000 profile

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-06-01

    A study was undertaken to determine the potential radiological implications of nuclear facilities in the combined watersheds of the Tennessee and Cumberland rivers, an area covering portions of 7 states of varied topography. The regional population in 1970 was about 4.6 million and is expected to increase to about 7 million by the year 2000. A 1973 projection estimated the installed electric generating capacity of the region to increase from a 1970 value of 45,000 megawatts to a total of 222,000 megawatts by the year 2000. In that year, about 144,000 megawatts were projected to be nuclear plants. The profile of the Tennessee Valley Region in the year 2000, as drawn from this report, contains the essential data for calculation of the radiological dose from operation of nuclear facilities in that year. Those calculations are reported in the companion document, DOE/ET-0064/2. Specifically, Volume I establishes the parameters describing where the people live, what they eat, the activities in which they engage, and the environmental surroundings that enable an evaluation of the potential radiation dose to the population. Airborne radionuclides from nuclear facilities in this zone may enter the study area and be deposited on the ground, on growing food, and on water surfaces. Consideration was not given to waterborne radionuclides external to the study region. 17 references. (MCW)

  18. Consistency of spherical, gravity-dominated dynamics with quasar high-ionization emission-line profiles

    Science.gov (United States)

    Kallman, T. R.; Wilkes, B. J.; Krolik, J. H.; Green, Richard

    1993-01-01

    Line profile data are used to test a simple kinematic model - spherically symmetric gravitational free fall - in which the number of free parameters is limited by requiring physical self-consistency. The predictions of this model are fitted to high-resolution spectra of the stronger rest-frame UV emission lines in 12 quasars with z of about 2. It is found that if all the lines are radiated predominantly from the illuminated faces of the emission-line clouds, the profiles of Ly-alpha, N V 1240 A, and C IV 1549 A can be simultaneously well fitted with very similar parameters for all 12 quasars. It is concluded that spherically symmetric gravitational free fall does not correctly describe the dynamics of quasar broad emission-line regions.

  19. Halpha line profile asymmetries and the chromospheric flare velocity field

    CERN Document Server

    Kuridze, D; Simões, P J A; van der Voort, L Rouppe; Carlsson, M; Jafarzadeh, S; Allred, J C; Kowalski, A F; Kennedy, M; Fletcher, L; Graham, D; Keenan, F P

    2015-01-01

    The asymmetries observed in the line profiles of solar flares can provide important diagnostics of the properties and dynamics of the flaring atmosphere. In this paper the evolution of the Halpha and Ca II 8542 {\\AA} lines are studied using high spatial, temporal and spectral resolution ground-based observations of an M1.1 flare obtained with the Swedish 1-m Solar Telescope. The temporal evolution of the Halpha line profiles from the flare kernel shows excess emission in the red wing (red asymmetry) before flare maximum, and excess in the blue wing (blue asymmetry) after maximum. However, the Ca II 8542 {\\AA} line does not follow the same pattern, showing only a weak red asymmetry during the flare. RADYN simulations are used to synthesise spectral line profiles for the flaring atmosphere, and good agreement is found with the observations. We show that the red asymmetry observed in Halpha is not necessarily associated with plasma downflows, and the blue asymmetry may not be related to plasma upflows. Indeed, w...

  20. Broad-line region structure and kinematics in the radio galaxy 3C 120

    CERN Document Server

    Kollatschny, W; Zetzl, M; Kaspi, S; Haas, M

    2014-01-01

    Broad emission lines originate in the surroundings of supermassive black holes in the centers of active galactic nuclei (AGN). One method to investigate the extent, structure, and kinematics of the BLR is to study the continuum and line profile variability in AGN. We selected the radio-loud Seyfert 1 galaxy 3C 120 as a target for this study. We took spectra with a high signal-to-noise ratio of 3C 120 with the 9.2m Hobby-Eberly Telescope between Sept. 2008 and March 2009. In parallel, we photometrically monitored the continuum flux at the Wise observatory. We analyzed the continuum and line profile variations in detail (1D and 2D reverberation mapping) and modeled the geometry of the line-emitting regions based on the line profiles. We show that the BLR in 3C 120 is stratified with respect to the distance of the line-emitting regions from the center with respect to the line widths (FWHM) of the rms profiles and with respect to the variability amplitude of the emission lines. The emission line wings of H{\\alpha...

  1. New Constraints on Quasar Broad Absorption and Emission Line Regions from Gravitational Microlensing

    Directory of Open Access Journals (Sweden)

    Damien Hutsemékers

    2017-09-01

    Full Text Available Gravitational microlensing is a powerful tool allowing one to probe the structure of quasars on sub-parsec scale. We report recent results, focusing on the broad absorption and emission line regions. In particular microlensing reveals the intrinsic absorption hidden in the P Cygni-type line profiles observed in the broad absorption line quasar H1413+117, as well as the existence of an extended continuum source. In addition, polarization microlensing provides constraints on the scattering region. In the quasar Q2237+030, microlensing differently distorts the Hα and CIV broad emission line profiles, indicating that the low- and high-ionization broad emission lines must originate from regions with distinct kinematical properties. We also present simulations of the effect of microlensing on line profiles considering simple but representative models of the broad emission line region. Comparison of observations to simulations allows us to conclude that the Hα emitting region in Q2237+030 is best represented by a Keplerian disk.

  2. FIR line profiles as probes of warm gas dynamics

    Science.gov (United States)

    Betz, A. L.; Boreiko, R. T.

    1995-01-01

    Measurements of the shapes, velocities, and intensities of FIR lines all help to probe the dynamics, physical associations, and excitation conditions of warm gas in molecular clouds. With this in mind, we have observed the J=9-8, 12-11,14-13, and 16-15 lines of (12)CO and the 158 micron line of C II in a number of positions in 4 selected clouds. The data were obtained with a laser heterodyne spectrometer aboard NASA's Kuiper Airborne Observatory. Line measurements at 0.6 km/s resolution allow us to resolve the profiles completely, and thereby to distinguish between UV-and shock-heating mechanisms for the high-excitation gas. For CO, the high-J linewidths lie in the range of 4-20 km/s (FWHM), similar to those observed for low-J (J less than 4) transitions in these sources. This correspondence suggests that the hotter gas (T = 200-600 K) is dynamically linked to the quiescent gas component, perhaps by association with the UV-heated peripheries of the numerous cloud clumps. Much of the C II emission is thought to emanate from these cloud peripheries, but the line profiles generally do not match those seen in CO. None of the observed sources show any evidence in high-J (12)CO emission for shock-excitation (i.e., linewidths greater than 30 km/s).

  3. Interpreting the Mg IIh andk Line Profiles of Mira Variables

    Science.gov (United States)

    Wood, B. E.; Karovska, M.

    2000-11-01

    We use radiative transfer calculations to reproduce the basic appearance of Mg II lines observed from Mira variables. These lines have centroids that are blueshifted by at least 30 km s-1 from the stellar rest frame. It is unlikely that flow velocities in the stellar atmospheres are this fast, so radiative transfer effects must be responsible for this behavior. Published hydrodynamic models predict the existence of cool, downflowing material above the shocked material responsible for the Mg II emission, and we demonstrate that scattering in this layer can result in Mg II profiles as highly blueshifted as those that are observed. However, our models also show that scattering within the shock plays an equally strong role in shaping the Mg II profiles, and our calculations illustrate the importance of partial redistribution and the effects of being out of ionization equilibrium.

  4. Alpha Virginis: line-profile variations and orbital elements

    CERN Document Server

    Harrington, David; Olguín, Enrique; Ilyin, Ilya; Berdyugina, Svetlana V; Lara, Bruno; Moreno, Edmundo

    2016-01-01

    Abridged: Alpha Virginis is a binary system whose proximity and brightness allow detailed investigations of the internal structure and evolution of stars undergoing time-variable tidal interactions. Previous studies have led to the conclusion that the internal structure of Spica's primary star may be more centrally condensed than predicted by theoretical models of single stars, raising the possibility that the interactions could lead to effects that are currently neglected in structure and evolution calculations. The key parameters in confirming this result are the values of the orbital eccentricity $e$, the apsidal period $U$, and the primary star's radius, R_1. We analyze the impact that line profile variability has on the derivation of its orbital elements and R_1. We use high SNR observations obtained in 2000, 2008, and 2013 to derive the orbital elements from fits to the radial velocity curves. We produce synthetic line profiles using an ab initio tidal interaction model. Results: The variations in the l...

  5. Inclination of Broad Line Region in Narrow Line and Broad Line Seyfert 1 Galaxies

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The sizes of the Broad Line Region (BLR) of some Seyfert 1 galax-ies and nearby quasars can be determined by the reverberation mapping method.Combining with the observed FWHM of Hβ emission line and assuming that themotion of BLR clouds is virialized, the black hole masses of these objects have beenestimated. However, this method strongly depends on the poorly-understood geom-etry and inclination of the BLR. On the other hand, a tight correlation between theblack hole mass and the bulge velocity dispersion was recently found for both activeand nearby inactive galaxies. This may provide another method, independent of theBLR geometry, for estimating the black hole mass. Using this method for estimatingthe black hole mass and combining with the measured BLR size and FWHM of Hβemission line, we derived the BLR inclination angles for 20 Seyfert I galaxies underthe assumption that the BLR is disk-like. The derived inclination angles agree wellwith those derived previously by fitting the UV continuum and Hβ emission lineprofiles. Adopting a relation between the FWHMs of [OⅢ]λ5007 forbidden line andthe stellar velocity dispersion, we also estimated the BLR inclinations for 50 nar-row line Seyfert 1 galaxies (NLSls). We found that the inclinations of broad LineSeyfert 1 galaxies (BLS1s) are systematically greater than those of NLS1s, whichseldom exceed 30. This may be an important factor that leads to the differencesbetween NLS1s and BLS1s if the BLR of NLS1s is really disk-like.

  6. Alpha Virginis: line-profile variations and orbital elements

    Science.gov (United States)

    Harrington, David; Koenigsberger, Gloria; Olguín, Enrique; Ilyin, Ilya; Berdyugina, Svetlana V.; Lara, Bruno; Moreno, Edmundo

    2016-05-01

    Context. Alpha Virginis (Spica) is a B-type binary system whose proximity and brightness allow detailed investigations of the internal structure and evolution of stars undergoing time-variable tidal interactions. Previous studies have led to the conclusion that the internal structure of Spica's primary star may be more centrally condensed than predicted by theoretical models of single stars, raising the possibility that the interactions could lead to effects that are currently neglected in structure and evolution calculations. The key parameters in confirming this result are the values of the orbital eccentricity e, the apsidal period U, and the primary star's radius, R1. Aims: The aim of this paper is to analyze the impact that Spica's line profile variability has on the derivation of its orbital elements and to explore the use of the variability for constraining R1. Methods: We use high signal-to-noise and high spectral resolution observations obtained in 2000, 2008, and 2013 to derive the orbital elements from fits to the radial velocity curves. We produce synthetic line profiles using an ab initio tidal interaction model. Results: The general variations in the line profiles can be understood in terms of the tidal flows, whose large-scale structure is relatively fixed in the rotating binary system reference frame. Fits to the radial velocity curves yield e = 0.108 ± 0.014. However, the analogous RV curves from theoretical line profiles indicate that the distortion in the lines causes the fitted value of e to depend on the argument of periastron; i.e., on the epoch of observation. As a result, the actual value of e may be as high as 0.125. We find that U = 117.9 ± 1.8, which is in agreement with previous determinations. Using the value R1 = 6.8 R⊙ derived by Palate et al. (2013) the value of the observational internal structure constant k2,obs is consistent with theory. We confirm the presence of variability in the line profiles of the secondary star. RV

  7. The broad Fe K line profile in NGC 4151

    CERN Document Server

    Wang, J; Wang, T; Wang, Junxian.; Zhou, Youyuan.; Wang, Tinggui.

    1999-01-01

    We present an analysis of the Fe K line profile of NGC 4151 by using long ASCA observation data obtained in May 1995. The unprecedented good data quality, which is much better in the energy band around 6.4 keV than that of the famous 4.2-day ASCA observation of MCG -6-30-15 in July 1994, offers a unique opportunity to study the details of Fe K line profile. Apart from those characteristics already noticed in earlier ASCA observations on this object (Yaqoob et al. 1995): a broad and skewed profile, with a strong peak at about 6.4 keV and a large red wing extending to $\\sim$4 - 5 keV, which is remarkably similar to that of MCG -6-30-15, we also find a weak blue wing extending to about 8 keV, thanks to the good quality of the data. When fitted by a relativistic accretion disk line plus a narrow core at 6.4 keV, the data constrain the accretion disk to be nearly face-on, contrary to the edge-on geometry inferred from optical and UV observations. However, the extended blue wing can not be well fitted even after we...

  8. Relativistic emission lines from accreting black holes - The effect of disk truncation on line profiles

    CERN Document Server

    Müller, A; Mueller, Andreas; Camenzind, Max

    2004-01-01

    Relativistic emission lines generated by thin accretion disks around rotating black holes are an important diagnostic tool for testing gravity near the horizon. The iron K-line is of special importance for the interpretation of the X-ray emission of Seyfert galaxies, quasars and galactic X-ray binary systems. A generalized kinematic model is presented which includes radial drifts and non-Keplerian rotations for the line emitters. The resulting line profiles are obtained with an object-oriented ray tracer operating in the curved Kerr background metric. The general form of the Doppler factor is presented which includes all kinds of poloidal and toroidal motions near the horizon. The parameters of the model include the spin parameter, the inclination, the truncation and outer radius of the disk, velocity profiles for rotation and radial drift, the emissivity profile and a multi-species line-system. The red wing flux is generally reduced when radial drift is included as compared to the pure Keplerian velocity fie...

  9. AGN Broad Line Regions Scale with Bolometric Luminosity

    CERN Document Server

    Trippe, Sascha

    2015-01-01

    The masses of supermassive black holes in active galactic nuclei (AGN) can be derived spectroscopically via virial mass estimators based on selected broad optical/ultraviolet emission lines. These estimates commonly use the line width as a proxy for the gas speed and the monochromatic continuum luminosity as a proxy for the radius of the broad line region. However, if the size of the broad line region scales with bolometric rather than monochromatic AGN luminosity, mass estimates based on different emission lines will show a systematic discrepancy which is a function of the color of the AGN continuum. This has actually been observed in mass estimates based on H-alpha / H-beta and C IV lines, indicating that AGN broad line regions indeed scale with bolometric luminosity. Given that this effect seems to have been overlooked as yet, currently used single-epoch mass estimates are likely to be biased.

  10. On Spectral Line Profiles in Type Ia Supernova Spectra

    CERN Document Server

    Foley, Ryan J

    2013-01-01

    We present a detailed analysis of spectral line profiles in Type Ia supernova (SN Ia) spectra. We focus on the feature at ~3500 - 4000 A, which is commonly thought to be caused by blueshifted absorption of Ca H&K. Unlike some other spectral features in SN Ia spectra, this feature often has two overlapping (blue and red) components. It is accepted that the red component comes from photospheric calcium. However, it has been proposed that the blue component is caused by either high-velocity calcium (from either abundance or density enhancements above the photosphere of the SN) or Si II 3858. By looking at multiple data sets and model spectra, we conclude that the blue component of the Ca H&K feature is caused by Si II 3858 for most SNe Ia. The strength of the Si II 3858 feature varies strongly with the light-curve shape of a SN. As a result, the velocity measured from a single-Gaussian fit to the full line profile correlates with light-curve shape. The velocity of the Ca H&K component of the profile ...

  11. P-Cygni Profiles of Molecular Lines toward Arp 220 Nuclei

    CERN Document Server

    Sakamoto, Kazushi; Wilner, David J; Black, John H; Conway, John E; Costagliola, Francesco; Peck, Alison B; Spaans, Marco; Wang, Junzhi; Wiedner, Martina C

    2009-01-01

    We report ~100 pc (0.3") resolution observations of (sub)millimeter HCO+ and CO lines in the ultraluminous infrared galaxy Arp 220. The lines peak at two merger nuclei, with HCO+ being more spatially concentrated than CO. Asymmetric line profiles with blueshifted absorption and redshifted emission are discovered in HCO+(3-2) and (4-3) toward the two nuclei and in CO(3-2) toward one nucleus. We suggest that these P-Cygni profiles are due to ~100 km/s outward motion of molecular gas from the nuclei. This gas is most likely outflowing from the inner regions of the two nuclear disks rotating around individual nuclei, clearing the shroud around the luminosity sources there.

  12. The Kinematics of Quasar Broad Emission Line Regions Using a Disk-Wind Model

    Science.gov (United States)

    Yong, Suk Yee; Webster, Rachel L.; King, Anthea L.; Bate, Nicholas F.; O'Dowd, Matthew J.; Labrie, Kathleen

    2017-09-01

    The structure and kinematics of the broad line region in quasars are still unknown. One popular model is the disk-wind model that offers a geometric unification of a quasar based on the viewing angle. We construct a simple kinematical disk-wind model with a narrow outflowing wind angle. The model is combined with radiative transfer in the Sobolev, or high velocity, limit. We examine how angle of viewing affects the observed characteristics of the emission line. The line profiles were found to exhibit distinct properties depending on the orientation, wind opening angle, and region of the wind where the emission arises.

  13. Chromospheric and Transition region He lines during a flare

    Science.gov (United States)

    Falchi, A.; Mauas, P. J. D.; Andretta, V.; Teriaca, L.; Cauzzi, G.; Falciani, R.; Smaldone, L. A.

    An observing campaign (SOHO JOP 139), coordinated between ground based and SOHO instruments, has been planned to obtain simultaneous spectroheliograms of the same area in several spectral lines. The chromospheric lines Ca II K, Hα and Na I D as well as He I 10830, 5876, 584 and 304 Ålines have been observed. These observations allow us to build semi-empirical models of the atmosphere before and during a small flare. With these models, constructed to match the observed line profiles, we can test the He abundance value.

  14. Molecular Lines of 13 Glactic Infrared Bubble Regions

    CERN Document Server

    Yan, Q Z; Zhang, B; Lu, D R; Chen, X; Tang, Z H

    2016-01-01

    We investigated the physical properties of molecular clouds and star formation processes around infrared bubbles which are essentially expanding HII regions. We performed observations of 13 galactic infrared bubble fields containing 18 bubbles. Five molecular lines, 12CO (J=1-0), 13CO (J=1-0), C18O(J=1-0), HCN (J=1-0), and HCO+ (J=1-0), were observed, and several publicly available surveys, GLIMPSE, MIPSGAL, ATLASGAL, BGPS, VGPS, MAGPIS, and NVSS, were used for comparison. We find that these bubbles are generally connected with molecular clouds, most of which are giant. Several bubble regions display velocity gradients and broad shifted profiles, which could be due to the expansion of bubbles. The masses of molecular clouds within bubbles range from 100 to 19,000 solar mass, and their dynamic ages are about 0.3-3.7 Myr, which takes into account the internal turbulence pressure of surrounding molecular clouds. Clumps are found in the vicinity of all 18 bubbles, and molecular clouds near four of these bubbles w...

  15. Asymmetry of the natural line profile for the hydrogen atom.

    Science.gov (United States)

    Labzowsky, L N; Solovyev, D A; Plunien, G; Soff, G

    2001-10-01

    The asymmetry of the natural line profile for transitions in hydrogenlike atoms is evaluated within a QED framework. For the Lyman- alpha 1s-2p absorption transition in neutral hydrogen this asymmetry results in an additional energy shift of 2.929 856 Hz. For the 2s(1/2)-2p(3/2) transition it amounts to -1.512 674 Hz. As a new feature this correction turns out to be process dependent. The quoted numbers refer to the Compton-scattering process.

  16. Comparative Metabolic Flux Profiling of Melanoma Cell Lines

    Science.gov (United States)

    Scott, David A.; Richardson, Adam D.; Filipp, Fabian V.; Knutzen, Christine A.; Chiang, Gary G.; Ronai, Ze'ev A.; Osterman, Andrei L.; Smith, Jeffrey W.

    2011-01-01

    Metabolic rewiring is an established hallmark of cancer, but the details of this rewiring at a systems level are not well characterized. Here we acquire this insight in a melanoma cell line panel by tracking metabolic flux using isotopically labeled nutrients. Metabolic profiling and flux balance analysis were used to compare normal melanocytes to melanoma cell lines in both normoxic and hypoxic conditions. All melanoma cells exhibited the Warburg phenomenon; they used more glucose and produced more lactate than melanocytes. Other changes were observed in melanoma cells that are not described by the Warburg phenomenon. Hypoxic conditions increased fermentation of glucose to lactate in both melanocytes and melanoma cells (the Pasteur effect). However, metabolism was not strictly glycolytic, as the tricarboxylic acid (TCA) cycle was functional in all melanoma lines, even under hypoxia. Furthermore, glutamine was also a key nutrient providing a substantial anaplerotic contribution to the TCA cycle. In the WM35 melanoma line glutamine was metabolized in the “reverse” (reductive) direction in the TCA cycle, particularly under hypoxia. This reverse flux allowed the melanoma cells to synthesize fatty acids from glutamine while glucose was primarily converted to lactate. Altogether, this study, which is the first comprehensive comparative analysis of metabolism in melanoma cells, provides a foundation for targeting metabolism for therapeutic benefit in melanoma. PMID:21998308

  17. Transcription profiles of non-immortalized breast cancer cell lines

    Directory of Open Access Journals (Sweden)

    Holland James F

    2006-04-01

    Full Text Available Abstract Background Searches for differentially expressed genes in tumours have made extensive use of array technology. Most samples have been obtained from tumour biopsies or from established tumour-derived cell lines. Here we compare cultures of non-immortalized breast cancer cells, normal non-immortalized breast cells and immortalized normal and breast cancer cells to identify which elements of a defined set of well-known cancer-related genes are differentially expressed. Methods Cultures of cells from pleural effusions or ascitic fluids from breast cancer patients (MSSMs were used in addition to commercially-available normal breast epithelial cells (HMECs, established breast cancer cell lines (T-est and established normal breast cells (N-est. The Atlas Human Cancer 1.2 cDNA expression array was employed. The data obtained were analysed using widely-available statistical and clustering software and further validated through real-time PCR. Results According to Significance Analysis of Microarray (SAM and AtlasImage software, 48 genes differed at least 2-fold in adjusted intensities between HMECs and MSSMs (p Conclusion The expression profiles of 1176 genes were determined in finite life-span cultures of metastatic breast cancer cells and of normal breast cells. Significant differences were detected between the finite life-span breast cancer cell cultures and the established breast cancer cell lines. These data suggest caution in extrapolating information from established lines for application to clinical cancer research.

  18. Modeling the water line emission from the high-mass star-forming region AFGL2591

    CERN Document Server

    Poelman, D R

    2007-01-01

    Context: observations of water lines are a sensitive probe of the geometry, dynamics and chemical structure of dense molecular gas. The launch of Herschel with on board HIFI and PACS allow to probe the behaviour of multiple water lines with unprecedented sensitivity and resolution. Aims: we investigate the diagnostic value of specific water transitions in high-mass star-forming regions. As a test case, we apply our models to the AFGL2591 region. Results: in general, for models with a constant water abundance, the ground state lines, i.e., 1_(10)-1_(01), 1_(11)-0_(00), and 2_(12)-1_(01), are predicted in absorption, all the others in emission. This behaviour changes for models with a water abundance jump profile in that the line profiles for jumps by a factor of ~10-100 are similar to the line shapes in the constant abundance models, whereas larger jumps lead to emission profiles. Asymmetric line profiles are found for models with a cavity outflow and depend on the inclination angle. Models with an outflow cav...

  19. Iron line profiles in Suzaku spectra of bare Seyfert galaxies

    CERN Document Server

    Patrick, A R; Porquet, D; Markowitz, A G; Lobban, A P; Terashima, Y

    2010-01-01

    We methodically model the broad-band Suzaku spectra of a small sample of six 'bare' Seyfert galaxies: Ark 120, Fairall 9, MCG-02-14-009, Mrk 335, NGC 7469 and SWIFT J2127.4+5654. The analysis of bare Seyferts allows a consistent and physical modelling of AGN due to a weak amount of any intrinsic warm absorption, removing the degeneracy between the spectral curvature due to warm absorption and the red-wing of the Fe K region. Through effective modelling of the broad-band spectrum and investigating the presence of narrow neutral or ionized emission lines and reflection from distant material, we obtain an accurate and detailed description of the Fe K line region using models such as laor, kerrdisk and kerrconv. Results suggest that ionized emission lines at 6.7 keV and 6.97 keV (particularly Fe XXVI) are relatively common and the inclusion of these lines can greatly affect the parameters obtained with relativistic models i.e. spin, emissivity, inner radius of emission and inclination. Moderately broad components...

  20. The intermediate line region in active galactic nuclei

    CERN Document Server

    Adhikari, T P; Czerny, B; Hryniewicz, K; Ferland, G J

    2016-01-01

    We show that the recently observed suppression of the gap between the broad line region (BLR) and the narrow line region (NLR) in some AGN can be fully explained by an increase of the gas density in the emitting region. Our model predicts the formation of the intermediate line region (ILR) that is observed in some Seyfert galaxies by the detection of emission lines with intermediate velocity full width half maximum (FWHM) $\\sim$ 700 - 1200 km s$^{-1}$. These lines are believed to be originating from an ILR located somewhere between the BLR and NLR. As it was previously proved, the apparent gap is assumed to be caused by the presence of dust beyond the sublimation radius. Our computations with the use of {\\sc cloudy} photoionization code, show that the differences in the shape of spectral energy distribution (SED) from the central region of AGN, do not diminish the apparent gap in the line emission in those objects. A strong discontinuity in the line emission vs radius exists for all lines at the dust sublimat...

  1. Constraints on the outer radius of the broad emission line region of active galactic nuclei

    CERN Document Server

    Landt, Hermine; Elvis, Martin; Karovska, Margarita

    2014-01-01

    Here we present observational evidence that the broad emission line region (BELR) of active galactic nuclei (AGN) generally has an outer boundary. This was already clear for sources with an obvious transition between the broad and narrow components of their emission lines. We show that the narrow component of the higher-order Paschen lines is absent in all sources, revealing a broad emission line profile with a broad, flat top. This indicates that the BELR is kinematically separate from the narrow emission line region. We use the virial theorem to estimate the BELR outer radius from the flat top width of the unblended profiles of the strongest Paschen lines, Pa alpha and Pa beta, and find that it scales with the ionising continuum luminosity roughly as expected from photoionisation theory. The value of the incident continuum photon flux resulting from this relationship corresponds to that required for dust sublimation. A flat-topped broad emission line profile is produced by both a spherical gas distribution ...

  2. Reverberation Mapping of the Broad Line Region: Application to a Hydrodynamical Line-driven Disk Wind Solution

    Science.gov (United States)

    Waters, Tim; Kashi, Amit; Proga, Daniel; Eracleous, Michael; Barth, Aaron J.; Greene, Jenny

    2016-08-01

    The latest analysis efforts in reverberation mapping are beginning to allow reconstruction of echo images (or velocity-delay maps) that encode information about the structure and kinematics of the broad line region (BLR) in active galactic nuclei (AGNs). Such maps can constrain sophisticated physical models for the BLR. The physical picture of the BLR is often theorized to be a photoionized wind launched from the AGN accretion disk. Previously we showed that the line-driven disk wind solution found in an earlier simulation by Proga and Kallman is virialized over a large distance from the disk. This finding implies that, according to this model, black hole masses can be reliably estimated through reverberation mapping techniques. However, predictions of echo images expected from line-driven disk winds are not available. Here, after presenting the necessary radiative transfer methodology, we carry out the first calculations of such predictions. We find that the echo images are quite similar to other virialized BLR models such as randomly orbiting clouds and thin Keplerian disks. We conduct a parameter survey exploring how echo images, line profiles, and transfer functions depend on both the inclination angle and the line opacity. We find that the line profiles are almost always single peaked, while transfer functions tend to have tails extending to large time delays. The outflow, despite being primarily equatorially directed, causes an appreciable blueshifted excess on both the echo image and line profile when seen from lower inclinations (i≲ 45^\\circ ). This effect may be observable in low ionization lines such as {{H}}β .

  3. First evidence of non-Gaussian solar flare EUV spectral line profiles and accelerated non-thermal ion motion

    CERN Document Server

    Jeffrey, Natasha; Labrosse, Nicolas

    2016-01-01

    The properties of solar flare plasma can be determined from observations of optically thin EUV lines. The spectral line profiles emitted in a flaring MK plasma are expected to be dominated by Doppler broadening, producing Gaussian line profiles, if the underlying ion velocity distribution is Maxwellian. We look for non-Gaussian line profiles during a flare, that may indicate the presence of accelerated ion and/or plasma non-thermal velocity distributions. We study EUV spectral lines during a flare SOL2013-05-15T01:45 using the Hinode EUV Imaging Spectrometer (EIS). The flare is located close to the eastern solar limb. It has an extended loop structure, allowing different flare features: ribbons, hard X-ray (HXR) footpoints and the loop-top source to be clearly observed in EUV and X-rays. EUV line spectroscopy is performed in seven regions covering the flare features. We study the line profiles of isolated and unblended Fe XVI lines (262.9760 A) formed at temperatures of 2-4 MK. Suitable Fe XVI line profiles c...

  4. Multiwavelength laser line profile sensing for agricultural crop characterization

    Science.gov (United States)

    Strothmann, Wolfram; Ruckelshausen, Arno; Hertzberg, Joachim

    2014-05-01

    Triangulation-based laser line profile sensing is a widely used technique for precise and fast 3D measurement in industrial applications. More recently, it is used for applications in the area of outdoor agricultural sensing as well. However, in many agricultural applications high resolution range data by itself is insufficient. There is also a strong need for local spectral intensity information. As a consequence the combination of image-based range scanners with spectral imaging is often necessary. Under varying environmental conditions this is a tedious and error-prone problem, though. In contrast, the novel approach shown here allows capturing range data along with spectral laser reflectance and pixel-wise backscattering information at multiple, selectable wavelengths using a single sensor system. The system consists of multiple continuous wave (CW) line lasers simultaneously captured by a single monochrome imager. A system ready to capture 3 line lasers at 100 Hz was set up. Line lasers at different wavelengths in the visible and NIR range can be combined in accordance with the requirements of a specific application. Consecutively captured images are matched using sum of absolute differences (SAD) in order for tracking relative movement between the sensor system and the analyzed object. This allows normalizing images before the evaluation of reflectance and scattering. Furthermore, the SAD-based matching is used for accurate assembly of range and reflectance information gathered from different laser lines. It results in 3D point clouds with spectral laser reflectance and backscattering information at multiple, selectable wavelengths available for each point.

  5. Line profile modelling for multi-pixel CZT detectors

    Science.gov (United States)

    Chattopadhyay, T.; Vadawale, S. V.; Rao, A. R.; Bhattacharya, D.; Mithun, N. P. S.; Bhalerao, V.

    2016-07-01

    Cadmium Zinc Telluride (CZT) detectors have been the mainstay for hard X-ray astronomy for its high quantum efficiency, fine energy resolution, near room temperature operation, and radiation hardness. In order to fully utilize the spectroscopic capabilities of CZT detectors, it is important to generate accurate response matrix, which in turn requires precise modelling of the line profiles for the CZT detectors. We have developed a numerical model taking into account the mobility and lifetime of the charge carriers and intrpixel charge sharing for the CZT detectors. This paper describes the details of the modelling along with the experimental measurements of mobility, lifetime and charge sharing fractions for the CZT detector modules of thickness of 5 mm and 2.5 mm pixel size procured from Orbotech Medical Solutions (same modules used in AstroSat-CZTI).

  6. The Line-Profile Variations of Theta2 Tauri

    Science.gov (United States)

    Kennelly, E. J.; Walker, G. A. H.

    1996-04-01

    With a 5.4-hour time series of high-resolution CFHT spectra, the oscillations of the rapidly-rotating delta Scuti star Theta2 Tauri (A7 IV + A5 V) are investigated. Line-profile variations are discovered and identified with the spectrum of the primary star of this binary system. Radial velocity variations are derived from the data and analyzed to reveal an oscillation frequency near 13.7 cycles day^-1. Variations within the absorption profiles are analyzed with a Fourier-Doppler Imaging (FDI) technique to reveal that high-degree oscillations with a frequency of 16.1 cycles day ^-1 and an apparent degree of about l = 8 are also present in the star. Whereas the low-degree variations of Theta2 Tau have been shown to be consistent with p-modes of radial order n=2 or 3, the identification of the high-degree variations in terms of pressure modes requires confirmation with theoretical models. (SECTION: Stars)

  7. Impact of AIRS Thermodynamic Profile on Regional Weather Forecast

    Science.gov (United States)

    Chou, Shih-Hung; Zavodsky, Brad; Jedlovee, Gary

    2010-01-01

    Prudent assimilation of AIRS thermodynamic profiles and quality indicators can improve initial conditions for regional weather models. AIRS-enhanced analysis has warmer and moister PBL. Forecasts with AIRS profiles are generally closer to NAM analyses than CNTL. Assimilation of AIRS leads to an overall QPF improvement in 6-h accumulated precipitation forecasts. Including AIRS profiles in assimilation process enhances the moist instability and produces stronger updrafts and a better precipitation forecast than the CNTL run.

  8. A LINE SEARCH AND TRUST REGION ALGORITHM WITH TRUST REGION RADIUS CONVERGING TO ZERO

    Institute of Scientific and Technical Information of China (English)

    Jin-yan Fan; Wen-bao Ai; Qun-ying Zhang

    2004-01-01

    In this paper, we present a new line search and trust region algorithm for unconstrained optimization problem with the trust region radius converging to zero. The new trust region algorithm performs a backtracking line search from the failed. Point instead of resolving the subproblem when the trial step results in an increase in the objective function. We show that the algorithm preserves the convergence properties of the traditional trust region algorithms. Numerical results are also given.

  9. Analysis of the solar coronal green line profiles from eclipse observations

    CERN Document Server

    Prabhakar, Maya; Chandrasekhar, T

    2013-01-01

    Analysis of the solar coronal green line profiles reveals information regarding the physical conditions of the solar corona like temperature, density, Doppler velocity, non-thermal velocity etc. It provides insights to the unresolved problems like the coronal heating and the acceleration of the solar winds. Recent studies have reported excess blueshifts in the coronal line profiles and are interpreted as due to nanoflare heating, type II spicules and nascent solar wind flow. We have analyzed a time series of Fabry-Perot interferograms of the solar corona obtained during the total solar eclipse of 2001 June 21 from Lusaka, Zambia. The spatial behavior of the coronal green line profiles were examined and variations in intensity, linewidth, Doppler velocity and line asymmetry were obtained. Several line profiles showed asymmetry indicating the presence of multicomponents. Such line profiles were fitted with double Gaussian curves. It has been found that 42% of the line profiles were single components, 34% were b...

  10. The extended narrow line region of NGC 4151. I. Emission line ratios and their implications

    OpenAIRE

    Penston, M. V.; Robinson, A.; Alloin, D.; Appenzeller, I.; Aretxaga, I.; Axon, D.J.; Baribaud, T.; Barthel, P.; Baum, S. A.; Boisson, C.; de Bruyn, A. G.; Clavel, J.; Colina, L.; Dennefeld, M.; Angeles I. Díaz

    1990-01-01

    This is an electronic version of an article published in Astronomy and Astrophysics. Penston, M.V. et al. The extended narrow line region of NGC 4151. I. Emission line ratios and their implications. Astronomy and Astrophysics 236 (1990): 53-62

  11. Microlensing of the broad-line region in the quadruply imaged quasar HE0435-1223

    CERN Document Server

    Braibant, L; Sluse, D; Anguita, T; García-Vergara, C J

    2014-01-01

    Using infrared spectra of the z = 1.693 quadruply lensed quasar HE0435-1223 acquired in 2009 with the spectrograph SINFONI at the ESO Very Large Telescope, we have detected a clear microlensing effect in images A and D. While microlensing affects the blue and red wings of the H{\\alpha} line profile in image D very differently, it de-magnifies the line core in image A. The combination of these different effects sets constraints on the line-emitting region; these constraints suggest that a rotating ring is at the origin of the H{\\alpha} line. Visible spectra obtained in 2004 and 2012 indicate that the MgII line profile is microlensed in the same way as the H{\\alpha} line. Our results therefore favour flattened geometries for the low-ionization line-emitting region, for example, a Keplerian disk. Biconical models cannot be ruled out but require more fine-tuning. Flux ratios between the different images are also derived and confirm flux anomalies with respect to estimates from lens models with smooth mass distrib...

  12. Diagnostics for the structure of AGNs’broad line regions with reverberation mapping data:confirmation of the two-component broad line region model

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    We re-examine the ten Reverberation Mapping(RM) sources with public data based on the two-component model of the Broad Line Region(BLR).In fitting their broad Hβ Mlines,six of them only need one Gaussian component,one of them has a double-peak profile,one has an irregular profile,and only two of them need two components,i.e.,a Very Broad Gaussian Component(VBGC) and an Inter-Mediate Gaussian Component(IMGC).The Gaussian components are assumed to come from two distinct regions in the two-component model;they are the Very Broad Line Region(VBLR) and the Inter-Mediate Line region(IMLR).The two sources with a two-component profile are Mrk 509 and NGC 4051.The time lags of the two components of both sources satisfy tIMLR/tVBLR=V 2VBLR/V 2IMLR,where tIMLR and tVBLR are the lags of the two components while VIMLR and VVBLR represent the mean gas velocities of the two regions,supporting the two-component model of the BLR of Active Galactic Nuclei(AGNs).The fact that most of these ten sources only have the VBGC confirms the assumption that RM mainly measures the radius of the VBLR;consequently,the radius obtained from the R-L relationship mainly represents the radius of VBLR.Moreover,NGC 4051,with a lag of about 5 days in the one component model,is an outlier on the R-L relationship as shown in Kaspi et al.(2005);however this problem disappears in our two-component model with lags of about 2 and 6 days for the VBGC and IMGC,respectively.

  13. Regional Disease Vector Ecology Profile Central Europe

    Science.gov (United States)

    2001-04-01

    the surveillance of this zoonosis in Central Europe. The primary mode of transmission in the region is by direct contact of the skin or conjunctivae...This constitutes true parasitism and is essentially a zoonosis . Obligate myiasis is a serious pathology. In humans, obligate myiasis results...infectious agent. xerophilic - tolerant of dry environments. zoonosis - an infectious disease of animals transmissible under natural conditions from

  14. Regional Disease Vector Ecology Profile. Southeast Asia

    Science.gov (United States)

    2009-06-01

    distributed throughout the region from coastal lowlands to over 1,500 m in the Himalayan foothills near the northern end of the Myanmar and Thailand border...albendazole) usually via DEC-fortified salt as recommended by the WHO. Indonesia, Myanmar, and Timor- Leste have shown progress with their MDA program...semiaquatic, occurring in the sand or mud of fresh, salt , or brackish water habitats, notably salt marshes and mangrove swamps. Many species occupy

  15. Regional profile, energy-impacted communities: Region VIII

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-03-01

    This report has data on population, administration, finance, housing, health and safety, human services, education, and water and sewage for 325 energy-impacted communities. A review of current and potential energy developments in the region shows over 900 energy resource impacts listed for the 325 impacted communities. Coal development represents over one-third of the developments listed. Communities reporting coal development are distributed as follows: Colorado (36), Montana (42), North Dakota (61), South Dakota (13), Utah (73), and Wyoming (35). Energy-conversion initiatives represent another high incidence of energy-resource impact, with uranium development following closely with 83 communities reporting uranium development impact in the region. These projections indicate continued development of regional energy resources to serve national energy requirements. The 325 impacted communities as reported: Colorado (46), Montana (73), North Dakota (62), South Dakota (21), Utah (80), and Wyoming (43) follow a distribution pattern similar to that of future projects which illustrates that no area of the region will escape the impacts of energy development. (ERA citation 04:041706)

  16. Line and continuum emission from the outer regions of accretion discs in active galactic nuclei. V. Detailed computational results

    Energy Technology Data Exchange (ETDEWEB)

    Dumont, A.M. (Observatoire de Paris, Section de Meudon, 92 (FR)); Collin-Souffrin, S. (Centre National de la Recherche Scientifique, 75 - Paris (FR). Inst. d' Astrophysique)

    1990-04-01

    This paper completes the results concerning the structure of the outer regions of accretion discs in Active Galactic Nuclei, and of their line emission spectra (profiles and line intensities). The computational method has been described in a series of previous papers.

  17. The HST view of the innermost narrow line region

    CERN Document Server

    Balmaverde, B; Moisio, D; Baldi, R D; Marconi, A

    2016-01-01

    We analyze the properties of the innermost narrow line region in a sample of low-luminosity AGN. We select 33 LINERs (bona fide AGN) and Seyfert galaxies from the optical spectroscopic Palomar survey observed by HST/STIS. We find that in LINERs the [NII] and [OI] lines are broader than the [SII] line and that the [NII]/[SII] flux ratio increases when moving from ground-based to HST spectra. This effect is more pronounced considering the wings of the lines. Our interpretation is that, as a result of superior HST spatial resolution, we isolate a compact region of dense ionized gas in LINERs, located at a typical distance of about 3 pc and with a gas density of about 10$^4$-10$^5$ cm$^{-3}$, which we identify with the outer portion of the intermediate line region (ILR). Instead, we do not observe these kinds of effects in Seyferts; this may be the result of a stronger dilution from the NLR emission, since the HST slit maps a larger region in these sources. Alternatively, we argue that the innermost, higher densi...

  18. Berry phases and profiles of line wings and rainbow satellites induced by optical collisions

    Science.gov (United States)

    Ciuryło, R.; Szudy, J.; Baylis, W. E.

    2015-09-01

    The concept of Berry phase is included in an analysis of the intensity distribution in far wings of pressure-broadened spectral lines emitted or absorbed by atoms placed in an external cone-rotating electric field. Particular attention is focused on frequency regions where rainbow satellite bands appear. A classical-path treatment that employs the time-dependent Schrödinger equation is used to derive an expression for the line shape, and it uses a dipole transition moment calculated with quasimolecular wave functions given by the Berry version of the adiabatic approximation. It is found that in the presence of an external rotating electric field, the intensity distribution in far wings can be expressed in terms of the universal line shape function of the unified Franck-Condon theory once energy shifts due to Stark and Berry effects are taken into account. We show that the influence of Berry phase in the profiles of the far wings can be manifested either in the form of deviations of observed profiles from the quasistatic distribution or the appearance of additional features in the vicinity of the maximum of the rainbow satellite band. As an example, the modification of the rainbow satellite at 162.3 nm in the red wing of the self-broadened Lyman-α line of hydrogen, caused by an external rotating electric field, is considered.

  19. The broad line region of narrow-line Seyfert 1 galaxies

    CERN Document Server

    Rodríguez-Pascual, P M; Santos-Lleó, M; Rodriguez-Pascual, Pedro M.; Santos-Lleo, Maria

    1997-01-01

    We have analyzed new and archival IUE observations of narrow-line Seyfert 1 galaxies (NLS1) in order to revise the ultraviolet (UV) properties of this sub-group of Active Galactic Nuclei (AGN). We have found broad wings in the strongest UV emission lines, ruling out the hypothesis that there is no broad line emission region in this type of objects. Since the similarities in spectral energy distributions from the far-infrared (FIR) to the soft X rays in both narrow-line and broad-line Seyfert 1 galaxies do not suggest that the nuclei of NLS1 are hidden from a direct view, we discuss the possibility that the line emitting material in NLS1 is optically thin.

  20. Correlation between asymmetric profiles in slits and standard prewetting lines

    Directory of Open Access Journals (Sweden)

    Leszek Szybisz

    2009-09-01

    Full Text Available The adsorption of Ar on substrates of Li is investigated within the framework of a density functional theory which includes an effective pair potential recently proposed. This approach yields good results for the surface tension of the liquid-vapor interface. The behavior of the adsorbate in the cases of a single planar wall and a slit geometry is analyzed as a function of temperature. Asymmetric density profiles are found for fluid confined in a slit built up of two identical planar walls leading to the spontaneous symmetry breaking (SSB effect. We found that the asymmetric solutions occur even above the wetting temperature $T_w$ in a range of average densities $ho^*_{ssb1} le ho^*_{av} le ho^*_{ssb2}$, which diminishes with increasing temperatures until its disappearance at the critical prewetting point $T_{m cpw}$. In this way a correlation between the disappearance of the SSB effect and the end of prewetting lines observed in the adsorption on a one-wall planar substrate is established. In addition, it is shown that a value for $T_{m cpw}$ can be precisely determined by analyzing the asymmetry coefficients.

  1. Imaging spectrophotometry of ionized gas in NGC 1068. I - Kinematics of the narrow-line region

    Science.gov (United States)

    Cecil, Gerald; Bland, Jonathan; Tully, R. Brent

    1990-01-01

    The kinematics of collisionally excited forbidden N II 6548, 6583 across the inner 1 arcmin diameter of the nearby Seyfert galaxy NGC 1068 is mapped using an imaging Fabry-Perot interferometer and low-noise CCD. The stack of monochromatic images, which spatially resolved the high-velocity gas, was analyzed for kinematic and photometric content. Profiles agree well with previous long-slit work, and their complete spatial coverage makes it possible to constrain the gas volume distribution. It is found that the narrow-line region is distributed in a thick center-darkened, line-emitting cylinder that envelopes the collimated radio jet. Three distinct kinematic subsystems, of which the cylinder is composed, are discussed in detail. Detailed behavior of the emission-line profiles, at the few points in the NE quadrant with simple kinematics, argues that the ionized gas develops a significant component of motion perpendicular to the jet axis.

  2. Evidence for two spatially separated UV continuum emitting regions in the Cloverleaf broad absorption line quasar

    CERN Document Server

    Sluse, D; Anguita, T; Braibant, L; Riaud, P

    2015-01-01

    Testing the standard Shakura-Sunyaev model of accretion is a challenging task because the central region of quasars where accretion takes place is unresolved with telescopes. The analysis of microlensing in gravitationally lensed quasars is one of the few techniques which can test this model, yielding to the measurement of the size and of the temperature profile of the accretion disc. We present spectroscopic observations of the gravitationally lensed broad absorption line quasar H1413+117, which reveal partial microlensing of the continuum emission that appears to originate from two separated regions, a microlensed region corresponding the compact accretion disc, and a non-microlensed region, more extended and contributing to at least 30\\% of the total UV-continuum flux. Because this extended continuum is occulted by the broad absorption line clouds, it is not associated to the host galaxy, but rather to light scattered in the neighbourhood of the central engine. We measure the amplitude of microlensing of t...

  3. The Structure of the Broad-Line Region in Well-Studied AGNs

    Science.gov (United States)

    Peterson, Bradley M.; Ferland, Gary J.

    1997-01-01

    Large amounts of high quality UV and optical data have been obtained in massive multi-wavelength monitoring campaigns on a small number of active galactic nuclei, and these data are changing our understanding of the central engines in these sources in a fundamental way. Preliminary analyses have shown that more comprehensive approaches will be necessary to make full use of these data. We propose to undertake a complete set of photoionization equilibrium calculations with a state-of-the-art computer code in order to determine the radial structure of the broad-line region in a way that is consistent with the emission-line fluxes, profiles, and transfer functions.

  4. Kinetic-Energy Distribution of D(2p) Atoms from Analysis of the D Lyman-Alpha Line Profile

    Science.gov (United States)

    Ciocca, M.; Ajello, Joseph M.; Liu, Xianming; Maki, Justin

    1997-01-01

    The kinetic-energy distribution of D(2p) atoms resulting from electron-impact dissociation of D2 has been measured. A high-resolution vacuum ultraviolet spectrometer was employed for the first measurement of the D Lyman-alpha (D L(alpha)) emission line profiles at 20- and 100-eV excitation energies. Analysis of the deconvoluted line profile of D L(alpha) at 100 eV reveals the existence of a narrow line central peak of 29+/-2 mA full width at half maximum and a broad pedestal wing structure about 190 mA wide. The wings of the line can be used to determine the fast atom distribution. The wings of D L(alpha) arise from dissociative excitation of a series of doubly excited states that cross the Franck-Condon region between 23 and 40 eV. The fast atom distribution at 100-eV electron impact energy spans the energy range from 1 to 10 eV with a peak value near 6 eV. Slow D(2p) atoms characterized by a distribution function with peak energy near 100 meV produce the central peak profile, which is nearly independent of the impact energy. The deconvoluted line profiles of the central peak at 20 eV for dissociative excitation of D2 and H2 are fitted with an analytical function for use in calibration of space flight instrumentation equipped with a D/H absorption cell. The kinetic-energy and line profile results are compared to similar measurements for H2. The absolute cross sections for the line center (slow atoms) and wings (fast atoms) and total emission line profile were measured from threshold to 400 eV. Analytical model coefficients are given for the energy dependence of the measured slow atom cross section.

  5. Simultaneous Ultraviolet and Optical Emission-line Profiles of Quasars: Implications for Black Hole Mass Determination

    CERN Document Server

    Ho, Luis C; Dong, Xiao-Bo; Greene, Jenny E; Ponti, Gabriele

    2012-01-01

    The X-shooter instrument on the VLT was used to obtain spectra of seven moderate-redshift quasars simultaneously covering the spectral range 3000 Ang to 2.5 microns. At z ~ 1.5, most of the prominent broad emission lines in the ultraviolet to optical region are captured in their rest frame. We use this unique dataset, which mitigates complications from source variability, to intercompare the line profiles of C IV 1549, C III] 1909, Mg II 2800, and Halpha and evaluate their implications for black hole mass estimation. We confirm that Mg II and the Balmer lines share similar kinematics and that they deliver mutually consistent black hole mass estimates with minimal internal scatter (< 0.1 dex) using the latest virial mass estimators. Although no virial mass formalism has yet been calibrated for C III], this line does not appear promising for such an application because of the large spread of its velocity width compared to lines of both higher and lower ionization; part of the discrepancy may be due to the di...

  6. Diverse Broad Line Region Kinematic Signatures From Reverberation Mapping

    CERN Document Server

    Denney, K D; Pogge, R W; Adair, A; Atlee, D W; Au-Yong, K; Bentz, M C; Bird, J C; Brokofsky, D J; Chisholm, E; Comins, M L; Dietrich, M; Doroshenko, V T; Eastman, J D; Efimov, Y S; Ewald, S; Ferbey, S; Gaskell, C M; Hedrick, C H; Jackson, K; Klimanov, S A; Klimek, E S; Kruse, A K; Ladéroute, A; Lamb, J B; Leighly, K; Minezaki, T; Nazarov, S V; Onken, C A; Petersen, E A; Peterson, P; Poindexter, S; Sakata, Y; Schlesinger, K J; Sergeev, S G; Skolski, N; Stieglitz, L; Tobin, J J; Unterborn, C; Vestergaard, M; Watkins, A E; Watson, L C; Yoshii, Y

    2009-01-01

    A detailed analysis of the data from a high sampling rate, multi-month reverberation mapping campaign, undertaken primarily at MDM Observatory with supporting observations from telescopes around the world, reveals that the Hbeta emission region within the broad line regions (BLRs) of several nearby AGNs exhibit a variety of kinematic behaviors. While the primary goal of this campaign was to obtain either new or improved Hbeta reverberation lag measurements for several relatively low luminosity AGNs (presented in a separate work), we were also able to unambiguously reconstruct velocity-resolved reverberation signals from a subset of our targets. Through high cadence spectroscopic monitoring of the optical continuum and broad Hbeta emission line variations observed in the nuclear regions of NGC 3227, NGC 3516, and NGC 5548, we clearly see evidence for outflowing, infalling, and virialized BLR gas motions, respectively.

  7. Lidar Observation of Tropopause Ozone Profiles in the Equatorial Region

    Science.gov (United States)

    Shibata, Yasukuni; Nagasawa, Chikao; Abo, Makoto

    2016-06-01

    Tropospheric ozone in the tropics zone is significant in terms of the oxidizing efficiency and greenhouse effect. However, in the upper troposphere, the ozone budget in the tropics has not been fully understood yet because of the sparsity of the range-resolved observations of vertical ozone concentration profiles. A DIAL (differential absorption lidar) system for vertical ozone profiles have been installed in the equatorial tropopause region over Kototabang, Indonesia (100.3E, 0.2S). We have observed large ozone enhancement in the upper troposphere, altitude of 13 - 17 km, concurring with a zonal wind oscillation associated with the equatorial Kelvin wave around the tropopause at equatorial region.

  8. Line Emission from Radiation-Pressurized HII Regions I: Internal Structure and Line Ratios

    CERN Document Server

    Yeh, Sherry C C; Krumholz, Mark R; Matzner, Christopher D; Tielens, Alexander G G M

    2013-01-01

    The emission line ratios [OIII]5007/H-beta and [NII]6584/H-alpha have been adopted as an empirical way to distinguish between the fundamentally different mechanisms of ionization in emission-line galaxies. However, detailed interpretation of these diagnostics requires calculations of the internal structure of the emitting HII regions, and these calculations depend on the assumptions one makes about the relative importance of radiation pressure and stellar winds. In this paper we construct a grid of quasi-static HII region models to explore how choices about these parameters alter HII regions' emission line ratios. We find that, when radiation pressure is included in our models, HII regions reach a saturation point beyond which further increases in the luminosity of the driving stars does not produce any further increase in effective ionization parameter, and thus does not yield any further alteration in an HII region's line ratio. We also show that, if stellar winds are assumed to be strong, the maximum possi...

  9. Effect of a progressive sound wave on the profiles of spectral lines. 2: Asymmetry of faint Fraunhofer lines. [absorption spectra

    Science.gov (United States)

    Kostyk, R. I.

    1974-01-01

    The absorption coefficient profile was calculated for lines of different chemical elements in a medium with progressive sound waves. Calculations show that (1) the degree and direction of asymmetry depend on the atomic ionization potential and the potential of lower level excitation of the individual line; (2) the degree of asymmetry of a line decreases from the center toward the limb of the solar disc; and (3) turbulent motions 'suppress' the asymmetry.

  10. Reverberation Modeling of the Broad Emission Line Region in NGC 5548

    Science.gov (United States)

    Bottorff, M. C.; Korista, K. T.; Shlosman, I.; Blandford, R. D.

    Long-term observations of broad-line region (BLR) in the Seyfert~1 galaxy NGC~5548 are analyzed and a critical comparison with the predictions of a hydromagnetically-driven outflow model of Emmering, Blandford and Shlosman is provided. This model is used to generate a time series of C~IV line profiles that have responded to a time varying continuum. We include cloud emission anisotropy, cloud obscuration, a CLOUDY-generated emissivity function and a narrow-line component which is added to the BLR component to generate the total line profiles. The model is driven with continuum input based on the monitoring campaigns of NGC~5548 reported in Clavel et al. and Korista et al., and the line strengths, profiles and lags are compared with the observations. The model is able to reproduce the basic features of CIV line variability in this active galactic nucleus, i.e., time evolution of the profile shape and strength of the C~IV emission line without varying the model parameters. The best fit model provides the effective size, the dominant geometry, the emissivity distribution and the 3D velocity field of the C~IV BLR and constrains the mass of the central black hole to about $3\\times 10^7\\ M_{\\odot}$. The inner part of the wind in NGC~5548 appears to be responsible for the anisotropically emitted CIV line, while its outer part remains dusty and molecular, thus having similar spectral characteristics to a molecular torus, although its dynamics is fundamentally different. The model predicts a differential response across the C~IV line profile, producing a red-side-first response in the relative velocity interval of $3,000-6,000 {\\rm km\\ s^{-1}}$ followed by the blue mid-wing and finally by the line core. Given that no adequate method in computing the errors for data lags and centroids exists in the literature, the {\\it data} cross-correlation function provides results which appear inconclusive, making any direct comparison with the model premature. Overall analysis

  11. Broad Line Region Physical Conditions along the Quasar Eigenvector 1 Sequence

    CERN Document Server

    Marziani, P; Negrete, C A; Dultzin, D; Zamfir, S; Bachev, R

    2010-01-01

    [Abridged] We compare broad emission line profiles and estimate line ratios for all major emission lines between Ly-alpha and H-beta in a sample of six quasars. The sources were chosen with two criteria in mind: the existence of high quality optical and UV spectra as well as the possibility to sample the spectroscopic diversity in the 4D Eigenvector 1 context . In the latter sense each source occupies a region (bin) in the FWHM(H-beta) vs. optical FeII strength plane that is significantly different from the others. High S/N H-beta emission line profiles are used as templates for modeling the other lines (Ly-alpha, CIV 1549, HeII 1640, Al III 1860, Si III] 1892, and Mg II 2800). We can adequately model all broad lines assuming the existence of three components distinguished by blueshifted, unshifted and redshifted centroids (indicated as blue, broad and very broad component respectively). The broad component (high electron density, low ionization parameter; high column density) is present in almost all type-1 ...

  12. Impact of Atmospheric Infrared Sounder (AIRS) Thermodynamic Profiles on Regional Precipitation Forecasting

    Science.gov (United States)

    Chou, S.-H.; Zavodsky, B. T.; Jedloved, G. J.

    2010-01-01

    In data sparse regions, remotely-sensed observations can be used to improve analyses and lead to better forecasts. One such source comes from the Atmospheric Infrared Sounder (AIRS), which together with the Advanced Microwave Sounding Unit (AMSU), provides temperature and moisture profiles in clear and cloudy regions with accuracy which approaches that of radiosondes. The purpose of this paper is to describe an approach to assimilate AIRS thermodynamic profile data into a regional configuration of the Advanced Research WRF (ARW) model using WRF-Var. Quality indicators are used to select only the highest quality temperature and moisture profiles for assimilation in clear and partly cloudy regions, and uncontaminated portions of retrievals above clouds in overcast regions. Separate error characteristics for land and water profiles are also used in the assimilation process. Assimilation results indicate that AIRS profiles produce an analysis closer to in situ observations than the background field. Forecasts from a 37-day case study period in the winter of 2007 show that AIRS profile data can lead to improvements in 6-h cumulative precipitation forecasts resulting from improved thermodynamic fields. Additionally, in a convective heavy rainfall event from February 2007, assimilation of AIRS profiles produces a more unstable boundary layer resulting in enhanced updrafts in the model. These updrafts produce a squall line and precipitation totals that more closely reflect ground-based observations than a no AIRS control forecast. The location of available high-quality AIRS profiles ahead of approaching storm systems is found to be of paramount importance to the amount of impact the observations will have on the resulting forecasts.

  13. Demystifying the coronal line region of active galactic nuclei: spatially resolved spectroscopy with HST

    CERN Document Server

    Mazzalay, Ximena; Komossa, S

    2010-01-01

    We present an analysis of STIS/HST optical spectra of a sample of ten Seyfert galaxies aimed at studying the structure and physical properties of the coronal-line region (CLR). The high-spatial resolution provided by STIS allowed us to resolve the CLR and obtain key information about the kinematics of the coronal-line gas, measure directly its spatial scale, and study the mechanisms that drive the high-ionisation lines. We find CLRs extending from just a few parsecs (~10 pc) up to 230 pc in radius, consistent with the bulk of the coronal lines (CLs) originating between the BLR and NLR, and extending into the NLR in the case of [FeVII] and [NeV] lines. The CL profiles strongly vary with the distance to the nucleus. We observed line splitting in the core of some of the galaxies. Line peak shifts, both red- and blue-shifts, typically reached 500 km/s, and even higher velocities (1000 km/s) in some of the galaxies. In general, CLs follow the same pattern of rotation curves as low-ionisation lines like [OIII]. Fro...

  14. The case for inflow of the broad-line region of active galactic nuclei

    CERN Document Server

    Gaskell, C Martin

    2015-01-01

    The high-ionization lines of the broad-line region (BLR) of thermal active galactic nuclei (AGNs) show blueshifts of a few hundred km/s to several thousand km/sec with respect to the low-ionization lines. This has long been thought to be due to the high-ionization lines of the BLR arising in a wind of which the far side of the outflow is blocked from our view by the accretion disc. Evidence for and against the disc-wind model is discussed. The biggest problem for the model is that velocity-resolved reverberation mapping repeatedly fails to show the expected kinematic signature of outflow of the BLR. The disc-wind model also cannot readily reproduce the red side of the line profiles of high-ionization lines. The rapidly falling density in an outflow makes it difficult to obtain high equivalent widths. We point out a number of major problems with associating the BLR with the outflows producing broad absorption lines. An explanation which avoids all these problems and satisfies the constraints of both the line p...

  15. A Tie2-driven BAC-TRAP transgenic line for in vivo endothelial gene profiling.

    Science.gov (United States)

    Santhosh, Devi; Huang, Zhen

    2016-03-01

    Recent technological innovations including bacterial artificial chromosome-based translating ribosome affinity purification (BAC-TRAP) have greatly facilitated analysis of cell type-specific gene expression in vivo, especially in the nervous system. To better study endothelial gene expression in vivo, we have generated a BAC-TRAP transgenic mouse line where the L10a ribosomal subunit is tagged with EGFP and placed under the control of the endothelium-specific Tie2 (Tek) promoter. We show that transgene expression in this line is widely, but specifically, detected in endothelial cells in several brain regions throughout pre- and postnatal development, as well as in other organs. We also show that this line results in highly significant enrichment of endothelium-specific mRNAs from brain tissues at different stages. This BAC-TRAP line therefore provides a useful genetic tool for in vivo endothelial gene profiling under various developmental, physiological, and pathological conditions. genesis 54:136-145, 2016. © 2016 Wiley Periodicals, Inc.

  16. The Structure of Narrow-Line Region in LINERs

    Institute of Scientific and Technical Information of China (English)

    Hai-Feng Dai; Ting-Gui Wang

    2008-01-01

    Low-ionization nuclear emission regions (LINERs) are present in a large fraction of local galaxies, while their connection to the more luminous active galactic nuclei (AGN) remains elusive. We analyze the narrow band images obtained by the Hubble Space Telescope (HST) in Hα+[NⅡ] and/or [OⅢ] band for 23 LINERs and low luminosity Seyfert galaxies in the sample of the Palomar Optical Spectroscopic Survey of nearby galaxies in an attempt to resolve the structure of Narrow Emission Line Regions (NLRs) of these objects. In all cases, NLRs are well resolved and their morphology differs from object to object. Clumps, linear structure, spiral arms or a ring are detected in a large fraction of the objects, while there is no significant difference between Seyfert galaxies and LINERs. We find that the NLR size and the narrow line luminosity are strongly correlated for both LINERs and low luminosity Seyfert galaxies, and that the size of Hα+[NⅡ] emission line region scales with Hα luminosity as RNLR∞L0.4±0.06Hα, consistent with an extension of the NLR size-luminosity relation defined for luminous Seyfert galaxies and quasars, to two orders of magnitude lower in luminosity and to lower activity levels. Our results suggest that NLRs in LINERs are similar to those of Seyfert galaxies, and they are powered by the central active galactic nucleus.

  17. High-resolution H-band spectroscopy of Be stars with SDSS-III/apogee. I. New Be stars, line identifications, and line profiles

    Energy Technology Data Exchange (ETDEWEB)

    Chojnowski, S. Drew; Majewski, Steven R.; Hall, Matthew; Beaton, Rachael; Burton, Adam; Damke, Guillermo; Wilson, John [Department of Astronomy, University of Virginia, P.O. Box 400325, Charlottesville, VA 22904-4325 (United States); Whelan, David G. [Department of Physics, Austin College, 900 N. Grand Ave., Sherman, TX 75090 (United States); Wisniewski, John P. [Department of Physics and Astronomy, The University of Oklahoma, 440 W. Brooks St., Norman, OK 73019 (United States); Shetrone, Matthew [Department of Astronomy, The University of Texas at Austin, 2515 Speedway, Stop C1400 Austin, Texas 78712-1205 (United States); Eikenberry, Steve [Department of Astronomy, University of Florida, 211 Bryant Space Science Center, Gainesville, FL 32611-2055 (United States); Hasselquist, Sten; Holtzman, Jon A.; Brewington, Howard; Brinkmann, J. [Apache Point Observatory and New Mexico State University, P.O. Box 59, Sunspot, NM, 88349-0059 (United States); Mészáros, Szabolcs [ELTE Gothard Astrophysical Observatory, 1H-9704 Szombathely, Szent Imre herceg st. 112 (Hungary); Nidever, David [Department of Astronomy, University of Michigan, 830 Dennison, 500 Church St., Ann Arbor, MI 48109-1042 (United States); Schneider, Donald P. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Zasowski, Gail [Department of Physics and Astronomy, Johns Hopkins University, Bloomberg Center for Physics and Astronomy, Room 366, 3400 N. Charles Street, Baltimore, MD 21218 (United States); Bizyaev, Dmitry, E-mail: drewski@virginia.edu [Institute for Gravitation and the Cosmos, The Pennsylvania State University, University Park, PA 16802 (United States); and others

    2015-01-01

    The Apache Point Observatory Galactic Evolution Experiment (APOGEE) has amassed the largest ever collection of multi-epoch, high-resolution (R∼22,500), H-band spectra for B-type emission line (Be) stars. These stars were targeted by APOGEE as telluric standard stars and subsequently identified via visual inspection as Be stars based on H i Brackett series emission or shell absorption in addition to otherwise smooth continua and occasionally non-hydrogen emission features. The 128/238 APOGEE Be stars for which emission had never previously been reported serve to increase the total number of known Be stars by ∼6%. Because the H band is relatively unexplored compared to other wavelength regimes, we focus here on identification of the H-band lines and analysis of the emission peak velocity separations (Δv{sub p}) and emission peak intensity ratios (V/R) of the usually double-peaked H i and non-hydrogen emission lines. H i Br11 emission is found to preferentially form in the circumstellar disks at an average distance of ∼2.2 stellar radii. Increasing Δv{sub p} toward the weaker Br12–Br20 lines suggests these lines are formed interior to Br11. By contrast, the observed IR Fe ii emission lines present evidence of having significantly larger formation radii; distinctive phase lags between IR Fe ii and H i Brackett emission lines further supports that these species arise from different radii in Be disks. Several emission lines have been identified for the first time including C i 16895, a prominent feature in the spectra for almost a fifth of the sample and, as inferred from relatively large Δv{sub p} compared to the Br11–Br20, a tracer of the inner regions of Be disks. Emission lines at 15760 Å and 16781 Å remain unidentified, but usually appear along with and always have similar line profile morphology to Fe ii 16878. Unlike the typical metallic lines observed for Be stars in the optical, the H-band metallic lines, such as Fe ii 16878, never exhibit any

  18. Impact of Atmospheric Infrared Sounder (AIRS) Thermodynamic Profiles on Regional Weather Forecasting

    Science.gov (United States)

    Chou, Shih-Hung; Zavodsky, Bradley T.; Jedlovee, Gary J.

    2010-01-01

    In data sparse regions, remotely-sensed observations can be used to improve analyses and lead to better forecasts. One such source comes from the Atmospheric Infrared Sounder (AIRS), which together with the Advanced Microwave Sounding Unit (AMSU), provides temperature and moisture profiles with accuracy comparable to that of radiosondes. The purpose of this paper is to describe a procedure to assimilate AIRS thermodynamic profile data into a regional configuration of the Advanced Research Weather Research and Forecasting (WRF-ARW) model using its three-dimension variational (3DVAR) analysis component (WRF-Var). Quality indicators are used to select only the highest quality temperature and moisture profiles for assimilation in both clear and partly cloudy regions. Separate error characteristics for land and water profiles are also used in the assimilation process. Assimilation results indicate that AIRS profiles produce an analysis closer to in situ observations than the background field. Forecasts from a 37-day case study period in the winter of 2007 show that AIRS profile data can lead to improvements in 6-h cumulative precipitation forecasts due to instability added in the forecast soundings by the AIRS profiles. Additionally, in a convective heavy rainfall event from February 2007, assimilation of AIRS profiles produces a more unstable boundary layer resulting in enhanced updrafts in the model. These updrafts produce a squall line and precipitation totals that more closely reflect ground-based observations than a no AIRS control forecast. The location of available high-quality AIRS profiles ahead of approaching storm systems is found to be of paramount importance to the amount of impact the observations will have on the resulting forecasts.

  19. The extended narrow line region of NGC 4151. I - Emission line ratios and their implications

    Science.gov (United States)

    Penston, M. V.; Robinson, A.; Alloin, D.; Appenzeller, I.; Aretxaga, I.; Axon, D. J.; Baribaud, T.; Barthel, P.; Baum, S. A.; Boisson, C.; de Bruyn, A. G.; Clavel, J.; Colina, L.; Dennefeld, M.; Diaz, A.; Dietrich, M.; Durret, F.; Dyson, J. E.; Gondhalekar, P.; van Groningen, E.; Jablonka, P.; Jackson, N.; Kollatschny, W.; Laurikainen, E.; Lawrence, A.; Masegosa, J.; McHardy, I.; Meurs, E. J. A.; Miley, G.; Moles, M.; O'Brien, P.; O'Dea, C.; del Olmo, A.; Pedlar, A.; Perea, J.; Perez, E.; Perez-Fournon, I.; Perry, J.; Pilbratt, G.; Rees, M.; Robson, I.; Rodriguez-Pascual, P.; Rodriguez Espinosa, J. M.; Santos-Lleo, M.; Schilizzi, R.; Stasińska, G.; Stirpe, G. M.; Tadhunter, C.; Terlevich, E.; Terlevich, R.; Unger, S.; Vila-Vilaro, V.; Vilchez, J.; Wagner, S. J.; Ward, M. J.; Yates, G. J.

    1990-09-01

    The paper presents the first results from long-slit spectra of the Seyfert galaxy NGC 4151 which give average diagnostic ratios of weak lines in the Extended Narrow Line Region (ENLR) of the galaxy and the first direct density measurement in an ENLR. These data confirm that the ENLR is kinematically undisturbed gas in the disk of the galaxy which is illuminated by an ionizing continuum stronger by a factor of 13 than a power law interpolated between recently observed ultraviolet and X-ray fluxes. Explanations of this apparent excess include a hot thermal continuum, time variations, and an anisotropic rotation field.

  20. Hudson River Sub-Bottom Profile Lines_r09272010

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Subbottom Profiler Tracklines. Data was collected November 5 to December 15, 2009, in the estuary north from Saugerties to Troy. Fugro utilized the GeoAcoustics...

  1. The Narrow Line Region of Narrow-Line Seyfert 1 Galaxies

    CERN Document Server

    Rodríguez-Ardila, A; Pastoriza, M G; Donzelli, C J

    2000-01-01

    This work studies the optical emission line properties and physical conditions of the narrow line region (NLR) of seven narrow-line Seyfert 1 galaxies (NLS1). Our results show that the flux carried out by the narrow component of H-beta is, on average, 50% of the total line flux. As a result, the [OIII] 5007/H-beta ratio emitted in the NLR varies from 1 to 5, instead of the universally adopted value of 10. This has strong implications for the required spectral energy distribution that ionizes the NLR gas. Photoionization models that consider a NLR composed of a combination of matter-bounded and ionization-bounded clouds are successful at explaining the low [OIII] 5007/H-beta ratio and the weakness of low-ionization lines of NLS1s. Variation of the relative proportion of these two type of clouds nicely reproduce the dispersion of narrow line ratios found among the NLS1 sample. Assuming similar physical model parameters of both NLS1s and the normal Seyfert 1 galaxy NGC 5548, we show that the observed differences...

  2. Narrow-line region gas kinematics of 24 264 optically selected AGN: the radio connection

    Science.gov (United States)

    Mullaney, J. R.; Alexander, D. M.; Fine, S.; Goulding, A. D.; Harrison, C. M.; Hickox, R. C.

    2013-07-01

    Using a sample of 24 264 optically selected active galactic nuclei (AGNs) from the SDSS DR7 data base, we characterize how the profile of the [O III] λ5007 emission line relates to bolometric luminosity (LAGN), Eddington ratio, radio loudness, radio luminosity (L1.4 GHz) and optical class (i.e. broad/narrow-line Seyfert 1, type 2) to determine what drives the kinematics of this kpc-scale line emitting gas. First, we use spectral stacking to characterize how the average [O III] λ5007 profile changes as a function of these five variables. After accounting for the known correlation between LAGN and L1.4 GHz, we report that L1.4 GHz has the strongest influence on the [O III] λ5007 profile, with AGNs of moderate radio luminosity (L1.4 GHz = 1023-1025 W Hz-1) having the broadest [O III] λ5007 profiles. Conversely, we find only a modest change in the [O III] λ5007 profile with increasing radio loudness and find no significant difference between the [O III] λ5007 profiles of broad- and narrow-line Seyfert 1s. When binned according to Eddington ratio, only the AGNs in our highest bin (i.e. >0.3) show any signs of having broadened [O III] λ5007 profiles, although the small numbers of such extreme AGNs in our sample mean we cannot rule out that other processes (e.g. radio jets) are responsible for this broadening. The [O III] λ5007 profiles of type 1 and type 2 AGNs show the same trends in terms of line width, but type 1 AGNs display a much stronger `blue wing', which we interpret as evidence of outflowing ionized gas. We perform multicomponent fitting to the Hβ, [O III] λλ4959, 5007, [N II] λλ6548, 6584 and Hα lines for all the AGNs in our sample to calculate the proportions of AGNs with broad [O III] λ5007 profiles. The individual fits confirm the results from our stacked spectra; AGNs with L1.4 GHz > 1023 W Hz-1 are roughly five times more likely to have extremely broad [O III] λ5007 lines (full width at half-maximum, FWHMAvg > 1000 km s-1) compared to

  3. Analysis of the coronal green line profiles: evidence of excess blueshifts

    CERN Document Server

    Raju, K P; Ashok, N M

    2011-01-01

    The coronal green line (Fe XIV 5303 A) profiles were obtained from Fabry-Perot interferometric observations of the solar corona during the total solar eclipse of 21 June 2001 from Lusaka, Zambia. The instrumental width is about 0.2 A and the spectral resolution is about 26000. About 300 line profiles were obtained within a radial range of 1.0-1.5 R\\odot and position angle coverage of about 240\\circ. The line profiles were fitted with single Gaussian and their intensity, Doppler velocity, and line width have been obtained. Also obtained are the centroids of the line profiles which give a measure of line asymmetry. The histograms of Doppler velocity show excess blueshifts while the centroids reveal a pre-dominant blue wing in the line profiles. It has been found that the centroids and the Doppler velocities are highly correlated. This points to the presence of multiple components in the line profiles with an excess of blueshifted components. We have then obtained the(Blue-Red) wing intensity which clearly revea...

  4. Map of the Galactic center region in the 1. 8 MeV Al-26 gamma-ray line

    Energy Technology Data Exchange (ETDEWEB)

    Von ballmoos, P.; Diehl, R.; Schoenfelder, V.

    1987-07-01

    The mapping of the Galactic center region in the 1.8 MeV gamma-ray line based on observations made with the MPI Compton telescope during a balloon flight is reported. The measured gamma-ray line profile and the intensity map of the Galactic center region are presented, and the measured map is compared with maps expected from distributions of those objects that have been suggested as possible sources. The consistency of the results with a point source at the Galactic center raises questions about the validity of the generally assumed origin of the gamma-ray line in interstellar space. 26 references.

  5. Microlensing of the broad line region in 17 lensed quasars

    CERN Document Server

    Sluse, D; Courbin, F; Meylan, G; Wambsganss, J

    2012-01-01

    When an image of a strongly lensed quasar is microlensed, the different components of its spectrum are expected to be differentially magnified owing to the different sizes of the corresponding emitting region. Chromatic changes are expected to be observed in the continuum while the emission lines should be deformed as a function of the size, geometry and kinematics of the regions from which they originate. Microlensing of the emission lines has been reported only in a handful of systems so far. In this paper we search for microlensing deformations of the optical spectra of pairs of images in 17 lensed quasars. This sample is composed of 13 pairs of previously unpublished spectra and four pairs of spectra from literature. Our analysis is based on a spectral decomposition technique which allows us to isolate the microlensed fraction of the flux independently of a detailed modeling of the quasar emission lines. Using this technique, we detect microlensing of the continuum in 85% of the systems. Among them, 80% s...

  6. Reaching Higher Densities for Laboratory White Dwarf Photospheres to Measure Spectroscopic Line Profiles

    CERN Document Server

    Falcon, Ross E; Gomez, T A; Schaeuble, M; Nagayama, T; Montgomery, M H; Winget, D E; Rochau, G A

    2016-01-01

    As part of our laboratory investigation of the theoretical line profiles used in white dwarf atmosphere models, we extend the electron-density ($n_{\\rm e}$) range measured by our experiments to higher densities (up to $n_{e}\\sim80\\times10^{16}$ cm$^{-3}$). Whereas inferred parameters using the hydrogen-$\\beta$ spectral line agree among different line-shape models for $n_{\\rm e}\\lesssim30\\times10^{16}$ cm$^{-3}$, we now see divergence between models. These are densities beyond the range previously benchmarked in the laboratory, meaning theoretical profiles in this regime have not been fully validated. Experimentally exploring these higher densities enables us to test and constrain different line-profile models, as the differences in their relative H-Balmer line shapes are more pronounced at such conditions. These experiments also aid in our study of occupation probabilities because we can measure these from relative line strengths.

  7. XRAYL: a program for producing idealized powder diffraction line profiles from overlapped powder patterns

    Energy Technology Data Exchange (ETDEWEB)

    Hubbard, C.R.; Morosin, B. [Sandia National Labs., Albuquerque, NM (United States); Stewart, J.M. [Maryland Univ., College Park, MD (United States)

    1996-09-01

    The X-ray diffraction patterns of samples of polycrystalline materials are used to identify and characterize phases. Very often the total (or composite) profile consists of a series of overlapping profiles. In many applications it is necessary to separate the component profiles from the total profile. (In this document the terms {ital profile, line}, and {ital peak} are used interchangeably to represent these features of X-ray or neutron diffraction patterns.) A computer program, XRAYL, first developed in the 1980s and subsequently enlarged and improved, allows the fitting of analytical functions to powder diffraction lines. The fitting process produces parameters of chosen profile functions, diffraction line by diffraction line. The resulting function parameters may then be used to generate ``idealized`` powder diffraction lines as counts at steps in 2{Omega}. The generated lines are effectively free of statistical noise and contributions from overlapping lines. Each separated line extends to background on both sides of the generated profile. XRAYL may, therefore, be used in X-ray powder diffraction profile analysis as a preprocessor program that is, separating peaks and feeding the ``resolved`` data to subsequent analysis programs. This self- contained document includes: (1) a description of the fitting functions coded into XRAYL, (2) an outline of the least-squares algorithm used in fitting the profile function, (3) the file formats and contents utilized by the computer code, (4) the user options and their presentation requirements for execution of the program, (5) an example of input and output for a test case, and (6) source code listings on a diskette.

  8. Mantle electrical conductivity profile of Niger delta region

    Indian Academy of Sciences (India)

    Daniel N Obiora; Francisca N Okeke; K Yumoto; Stan O Agha

    2014-06-01

    The mantle electrical conductivity-depth profile of the Niger delta region in Nigeria has been determined using solar quiet day ionospheric current (Sq).The magnetometer data obtained in 2010 from geomagnetic stations installed in Lagos by magnetic dataset (MAGDAS) in 2008 and data from magnetometers installed in some parts of Niger delta by Center for Basic Space Science, University of Nigeria, Nsukka, were employed in this study. Gauss spherical harmonic analysis (SHA) method was used to separate the internal and external field contributions to Sq current system. The result depicted that the conductivity profile rose steadily from about 0.032 S/m at a depth of 89 km to 0.041 S/m at 100 km and 0.09 S/m at 221 km. This high conductivity region agreed with the global seismic low velocity region, the asthenosphere. The conductivity profile continued increasing downward until it got to 0.157 S/m at a depth of about 373 km (close to the base of upper mantle), 0.201 S/m at 784 km and reached 0.243 S/m at a depth of 1179 km at the lower mantle.

  9. Genome-wide nucleosome occupancy and DNA methylation profiling of four human cell lines

    Directory of Open Access Journals (Sweden)

    Aaron L. Statham

    2015-03-01

    Full Text Available DNA methylation and nucleosome positioning are two key mechanisms that contribute to the epigenetic control of gene expression. During carcinogenesis, the expression of many genes is altered alongside extensive changes in the epigenome, with repressed genes often being associated with local DNA hypermethylation and gain of nucleosomes at their promoters. However the spectrum of alterations that occur at distal regulatory regions has not been extensively studied. To address this we used Nucleosome Occupancy and Methylation sequencing (NOMe-seq to compare the genome-wide DNA methylation and nucleosome occupancy profiles between normal and cancer cell line models of the breast and prostate. Here we describe the bioinformatic pipeline and methods that we developed for the processing and analysis of the NOMe-seq data published by (Taberlay et al., 2014 [1] and deposited in the Gene Expression Omnibus with accession GSE57498.

  10. Seismic lines with digital seg-y profiles, northern Afghanistan (segyafg.shp)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This shapefile contains polylines that describe the location of seismic lines in northern Afghanistan for which digital seismic profiles in seg-y format are...

  11. Comparisons between direct and inverse approaches in problems of recovering the true profile of a spectral line

    CERN Document Server

    Mijovic, S

    2003-01-01

    Computer-supported techniques are introduced in the evaluation of experimental data and obtaining the real profile of spectral lines. The direct and inverse approaches were used. The MINUIT program from the packets of CERN's library was used to solve direct problems. Tikhonov's regularization method was also applied to solve the same problems in an inverse manner. Model functions were introduced to check the applicability limitation of these methods and make a comparison between them as well. The advantages and disadvantages of these approaches were shown. The procedures were applied to the measured profiles of He II's spectral lines in a pulsed low-pressure arc. The chosen lines are He II Paschen-alpha (468.6 nm) in the visible region and Balmer-beta (121.5 nm) in the VUV spectral region. The range of experimental errors was determined where both approaches have given reliable results. It was found that we can obtain the real profile of He II 468.6 nm and He II 121.5 nm spectral lines, using the regularizati...

  12. Fingerprinting of cell lines by directed amplification of minisatellite-region DNA (DAMD

    Directory of Open Access Journals (Sweden)

    Silva L.M.

    2001-01-01

    Full Text Available The development of in vitro propagation of cells has been an extraordinary technical advance for several biological studies. The correct identification of the cell line used, however, is crucial, as a mistaken identity or the presence of another contaminating cell may lead to invalid and/or erroneous conclusions. We report here the application of a DNA fingerprinting procedure (directed amplification of minisatellite-region DNA, developed by Heath et al. [Nucleic Acids Research (1993 21: 5782-5785], to the characterization of cell lines. Genomic DNA of cells in culture was extracted and amplified by PCR in the presence of VNTR core sequences, and the amplicons were separated by agarose gel electrophoresis. After image capture with a digital camera, the banding profiles obtained were analyzed using a software (AnaGel specially developed for the storage and analysis of electrophoretic fingerprints. The fingerprints are useful for construction of a data base for identification of cell lines by comparison to reference profiles as well as comparison of similar lines from different sources and periodic follow-up of cells in culture.

  13. Comparative Proteomic Profiling of Pancreatic Ductal Adenocarcinoma Cell Lines

    Science.gov (United States)

    Kim, Yikwon; Han, Dohyun; Min, Hophil; Jin, Jonghwa; Yi, Eugene C.; Kim, Youngsoo

    2014-01-01

    Pancreatic cancer is one of the most fatal cancers and is associated with limited diagnostic and therapeutic modalities. Currently, gemcitabine is the only effective drug and represents the preferred first-line treatment for chemotherapy. However, a high level of intrinsic or acquired resistance of pancreatic cancer to gemcitabine can contribute to the failure of gemcitabine treatment. To investigate the underlying molecular mechanisms for gemcitabine resistance in pancreatic cancer, we performed label-free quantification of protein expression in intrinsic gemcitabine-resistant and - sensitive human pancreatic adenocarcinoma cell lines using our improved proteomic strategy, combined with filter-aided sample preparation, single-shot liquid chromatography-mass spectrometry, enhanced spectral counting, and a statistical method based on a power law global error model. We identified 1931 proteins and quantified 787 differentially expressed proteins in the BxPC3, PANC-1, and HPDE cell lines. Bioinformatics analysis identified 15 epithelial to mesenchymal transition (EMT) markers and 13 EMT-related proteins that were closely associated with drug resistance were differentially expressed. Interestingly, 8 of these proteins were involved in glutathione and cysteine/methionine metabolism. These results suggest that proteins related to the EMT and glutathione metabolism play important roles in the development of intrinsic gemcitabine resistance by pancreatic cancer cell lines. PMID:25518923

  14. Interface Profiles near Three-Phase Contact Lines in Electric Fields

    OpenAIRE

    Buehrle, Juergen; Herminghaus, Stephan; Mugele, Frieder

    2003-01-01

    Long-range electrostatic fields deform the surface profile of a conductive liquid in the vicinity of the contact line. We have investigated the equilibrium profiles by balancing electrostatic and capillary forces locally at the liquid vapor interface. Numerical results show that the contact angle at the contact line approaches Young's angle. Simultaneously, the local curvature displays a weak algebraic divergence. Furthermore, we present an asymptotic analytical model, which confirms these re...

  15. Narrow-line-width UV Bursts in the Transition Region above Sunspots Observed by IRIS

    Science.gov (United States)

    Hou, Zhenyong; Huang, Zhenghua; Xia, Lidong; Li, Bo; Madjarska, Maria S.; Fu, Hui; Mou, Chaozhou; Xie, Haixia

    2016-10-01

    Various small-scale structures abound in the solar atmosphere above active regions, playing an important role in the dynamics and evolution therein. We report on a new class of small-scale transition region structures in active regions, characterized by strong emissions but extremely narrow Si iv line profiles as found in observations taken with the Interface Region Imaging Spectrograph (IRIS). Tentatively named as narrow-line-width UV bursts (NUBs), these structures are located above sunspots and comprise one or multiple compact bright cores at sub-arcsecond scales. We found six NUBs in two data sets (a raster and a sit-and-stare data set). Among these, four events are short-lived with a duration of ∼10 minutes, while two last for more than 36 minutes. All NUBs have Doppler shifts of 15–18 km s‑1, while the NUB found in sit-and-stare data possesses an additional component at ∼50 km s‑1 found only in the C ii and Mg ii lines. Given that these events are found to play a role in the local dynamics, it is important to further investigate the physical mechanisms that generate these phenomena and their role in the mass transport in sunspots.

  16. Narrow-line-width UV bursts in the transition region above Sunspots observed by IRIS

    CERN Document Server

    Hou, Zhenyong; Xia, Lidong; Li, Bo; Madjarska, Maria S; Fu, Hui; Mou, Chaozhou; Xie, Haixia

    2016-01-01

    Various small-scale structures abound in the solar atmosphere above active regions, playing an important role in the dynamics and evolution therein. We report on a new class of small-scale transition region structures in active regions, characterized by strong emissions but extremely narrow Si IV line profiles as found in observations taken with the Interface Region Imaging Spectrograph (IRIS). Tentatively named as Narrow-line-width UV bursts (NUBs), these structures are located above sunspots and comprise of one or multiple compact bright cores at sub-arcsecond scales. We found six NUBs in two datasets (a raster and a sit-and-stare dataset). Among these, four events are short-living with a duration of $\\sim$10 mins while two last for more than 36 mins. All NUBs have Doppler shifts of 15--18 km/s, while the NUB found in sit-and-stare data possesses an additional component at $\\sim$50 km/s found only in the C II and Mg II lines. Given that these events are found to play a role in the local dynamics, it is impo...

  17. Space Telescope Imaging Spectrograph Observations of High-Velocity Interstellar Absorption-Line Profiles in the Carina Nebula

    Science.gov (United States)

    Walborn, Nolan R.; Danks, Anthony C.; Vieira, Gladys; Landsman, Wayne B.

    2002-06-01

    An atlas of ultraviolet interstellar absorption-line profiles toward four stars in the Carina Nebula is presented. The observations have been made with the Space Telescope Imaging Spectrograph on the Hubble Space Telescope, with a resolving power of 114,000. Low-ionization, high-ionization, and excited-state lines from a wide array of chemical species are included. Extensive measurements of radial velocities, velocity dispersions, and column densities of individual components in these profiles are also given. The unprecedented capabilities of STIS reveal many more velocity components than previously known; most of the high-velocity components in previous observations with the International Ultraviolet Explorer are now resolved into multiple subcomponents, and even higher velocities are seen. The great range of line strengths available permits the detection of the low-velocity components in the weakest lines, and progressively higher velocities in stronger lines (in which the low-velocity components become completely blended). The weak and high-ionization lines trace global structure in the H II region, while the strong low-ionization lines show intricate high-velocity structure that likely originates relatively near to the O stars observed. The extreme velocities found in the low-ionization lines toward these four stars are -388 and +127 km s-1, with 23-26 resolved components in each. Some components in different stars may be related, but many are different in each line of sight. A remarkably well-defined Routly-Spitzer effect is found in this region. Temporal variations toward one star observed twice have already been reported. These measurements will be used in subsequent astrophysical analyses to further constrain the origins of the phenomena. Based on observations with the NASA/ESA Hubble Space Telescope obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract

  18. Plasma simulations of emission line regions in high energy environments

    Science.gov (United States)

    Richardson, Chris T.

    This dissertation focuses on understanding two different, but in each case extreme, astrophysical environments: the Crab Nebula and emission line galaxies. These relatively local objects are well constrained by observations and are test cases of phenomena seen at high-z where detailed observations are rare. The tool used to study these objects is the plasma simulation code known as Cloudy. The introduction provides a brief summary of relevant physical concepts in nebular astrophysics and presents the basic features and assumptions of Cloudy. The first object investigated with Cloudy, the Crab Nebula, is a nearby supernova remnant that previously has been subject to photoionization modeling to reproduce the ionized emission seen in the nebula's filamentary structure. However, there are still several unanswered questions: (1) What excites the H2 emitting gas? (2) How much mass is in the molecular component? (3) How did the H2 form? (4) What is nature of the dust grains? A large suite of observations including long slit optical and NIR spectra over ionized, neutral and molecular gas in addition to HST and NIR ground based images constrain a particularly bright region of H2 emission, Knot 51, which exhibits a high excitation temperature of ˜3000 K. Simulations of K51 revealed that only a trace amount of H2 is needed to reproduce the observed emission and that H2 forms through an uncommon nebular process known as associative detachment. The final chapters of this dissertation focus on interpreting the narrow line region (NLR) in low-z emission line galaxies selected by a novel technique known as mean field independent component analysis (MFICA). A mixture of starlight and radiation from an AGN excites the gas present in galaxies. MFICA separates galaxies over a wide range of ionization into subsets of pure AGN and pure star forming galaxies allowing simulations to reveal the properties responsible for their observed variation in ionization. Emission line ratios can

  19. A line-profile analysis of the large-amplitude beta Cephei star xi1 Canis Majoris

    NARCIS (Netherlands)

    Saesen, S.; Briquet, M.; Aerts, C.C.

    2006-01-01

    We present a detailed line-profile study of the beta Cephei star xi1 Canis Majoris, for which we have assembled numerous high-resolution spectra over a period of 4.5 years. It is the first time that the line-profile variations of this star have been analysed. We focused on the Si III line profiles c

  20. Interface Profiles near Three-Phase Contact Lines in Electric Fields

    NARCIS (Netherlands)

    Buehrle, Juergen; Herminghaus, Stephan; Mugele, Frieder

    2003-01-01

    Long-range electrostatic fields deform the surface profile of a conductive liquid in the vicinity of the contact line. We have investigated the equilibrium profiles by balancing electrostatic and capillary forces locally at the liquid vapor interface. Numerical results show that the contact angle at

  1. Searching for Line Profile Variability in HgMn Stars

    CERN Document Server

    Turcotte, S; Knoglinger, P

    2002-01-01

    Spectra of four non-magnetic chemically peculiar late B type stars (HgMn) stars are analysed to detect periodic spectral line variations (LPVs). A procedure developed to study LPVs in Slowly Pulsating B stars has been adopted as pulsational properties of HgMn stars should be expected to be similar. In the preliminary results discussed here no conclusive evidence for periodic LPVs was uncovered. A more sensitive re-analysis of the data is under way.

  2. Internet Teaching By Style: Profiling the On-line Professor

    Directory of Open Access Journals (Sweden)

    Sharon Strand

    2000-01-01

    Full Text Available The goal of this article is to offer the results of a pilot study which examined the personality type and teaching style preferences of faculty who elected to teach an on-line course. The article will present a description of personality assessments, including the Myers-Briggs Type Indicator (MBTI and Anthony Gregorc's Transaction Ability Inventory used to determine teaching tendencies and styles. In addition, a structured written questionnaire developed by the researchers was used to assess teacher satisfaction with worldwide web-based instruction. Utilizing the results of these psychological assessments, a preliminary analysis of the personal characteristics of college professors who chose to teach on line will be presented. This pilot study found that some preferred teaching styles may be more compatible with the dynamics of distance learning formats. By determining successful teaching styles for on-line courses, we can develop more effective faculty development programs to assist others in successfully transitioning into the cyber-teaching and learning environment.

  3. Measurement of Plasma Ion Temperature and Flow Velocity from Chord-Averaged Emission Line Profile

    Indian Academy of Sciences (India)

    Xu Wei

    2011-03-01

    The distinction between Doppler broadening and Doppler shift has been analysed, the differences between Gaussian fitting and the distribution of chord-integral line shape have also been discussed. Local ion temperature and flow velocity have been derived from the chord-averaged emission line profile by a chosen-point Gaussian fitting technique.

  4. Epoch-dependent absorption line profile variability in lambda Cep

    CERN Document Server

    Uuh-Sonda, J M; Eenens, P; Mahy, L; Palate, M; Gosset, E; Flores, C A

    2014-01-01

    We present the analysis of a multi-epoch spectroscopic monitoring campaign of the O6Ief star lambda Cep. Previous observations reported the existence of two modes of non-radial pulsations in this star. Our data reveal a much more complex situation. The frequency content of the power spectrum considerably changes from one epoch to the other. We find no stable frequency that can unambiguously be attributed to pulsations. The epoch-dependence of the frequencies and variability patterns are similar to what is seen in the wind emission lines of this and other Oef stars, suggesting that both phenomena likely have the same, currently still unknown, origin.

  5. Absorption line profile recovery based on TDLS and MEMS micro-mirror for photoacoustic gas sensing.

    Science.gov (United States)

    Li, Li; Arsad, Norhana; Stewart, George; Thursby, Graham; Uttamchandani, Deepak; Culshaw, Brian; Yi-ding, Wang

    2011-07-01

    A novel and efficient absorption line recovery technique is presented. A micro-electromechanical systems (MEMS) mirror driven by an electrothermal actuator is used to generate laser intensity modulation through the mirror reflection. Tunable diode laser spectroscopy (TDLS) and photoacoustic spectroscopy (PAS) are used to recover the target absorption line profile which is compared with the theoretical Voigt profile. The target gas is 0.01% acetylene (C2H2) in a nitrogen host gas. The laser diode wavelength is swept across the P17 absorption line of acetylene at 1535.4 nm by a current ramp, and an erbium-doped fibre amplifier (EDFA) is used to enhance the optical intensity and increase the signal-to-noise ratio (SNR). A SNR of about 35 is obtained with 100 mW laser power from the EDFA. Good agreement is achieved between the experimental results and the theoretical simulation for the P17 absorption line profile.

  6. Absorption Line Profile Recovery Based on TDLS and MEMS Micro-Mirror for Photoacoustic Gas Sensing

    Institute of Scientific and Technical Information of China (English)

    LI Li; Norhana Arsad; George Stewart; Graham Thursby; Deepak Uttamchandani; Brian Culshaw; WANG Yi-ding

    2011-01-01

    A novel and efficient absorption line recovery technique is presented. A micro-electromechanical systems (MEMS) mirror driven by an electrothermal actuator is used to generate laser intensity modulation through the mirror reflection. Tunable diode laser spectroscopy (TDLS) and photoacoustic spectroscopy (PAS) are used to recover the target absorption line profile which is compared with the theoretical Voigt profile. The target gas is 0.01% acetylene (C2 H2 ) in a nitrogen host gas. The laser diode wavelength is swept across the P17 absorption line of acetylene at 1 535.4 nm by a current ramp, and an erbium-doped fibre amplifier (EDFA) is used to enhance the optical intensity and increase the signal-to-noise ratio (SNR). A SNR of about 35 is obtained with 100 mW laser power from the EDFA Good agreement is achieved between the experimental results and the theoretical simulation for the P17 absorption line profile.

  7. Outflow and metallicity in the broad-line region of low-redshift active galactic nuclei

    CERN Document Server

    Shin, Jaejin; Woo, Jong-Hak

    2016-01-01

    Outflows in active galactic nuclei (AGNs) are crucial to understand in investigating the co-evolution of supermassive black holes (SMBHs) and their host galaxies since outflows may play an important role as an AGN feedback mechanism. Based on the archival UV spectra obtained with HST and IUE, we investigate outflows in the broad-line region (BLR) in low-redshift AGNs (z < 0.4) through the detailed analysis of the velocity profile of the CIV emission line. We find a dependence of the outflow strength on the Eddington ratio and the BLR metallicity in our low-redshift AGN sample, which is consistent with the earlier results obtained for high-redshift quasars. These results suggest that the BLR outflows, gas accretion onto SMBH, and past star-formation activity in the host galaxies are physically related in low-redshift AGNs as in powerful high-redshift quasars.

  8. Variability of Hell and hydrogen line profiles in the spectrum of HD 93521

    Science.gov (United States)

    Rzaev, A. Kh.; Panchuk, V. E.

    2008-03-01

    We have studied the variability of the Hell λλ 4686 and 5411 Å H β, and H α lines in the spectrum of the pulsating star HD 93521. All these line profiles display the same variability pattern relative to the average profiles: a sinusoidal wave that moves systematically from the short-to the long-wavelength wing of the profile. This variability is due to non-radial pulsations. To study the pulsation movements and stratification of the radial velocity in the atmosphere of HD 93521, we analyzed the variability of the radial velocities measured individually for the blue and red halves of the absorption profile at the half-level of the line intensity. The periods and amplitudes of this radial-velocity variability are different for different lines and are well correlated with their central depths. In the transition from weak to strong lines (i.e., from lower to upper layers of the atmosphere), the period of the radial-velocity variations measured using both halves of the absorption profile increases, while its amplitude decreases. When the morphology and variability of photospheric and wind-driven lines are compared, it is clear that the variability of their absorption components is due to the same process—non-radial pulsations. In this way, the non-radial pulsations partly affect the variability of the stellar wind. The effect of the stellar wind on the profiles of strong lines is observed as a variable absorption feature that moves along the profiles synchronous with the axial rotation of the star.

  9. Iris si iv line profiles: An indication for the plasmoid instability during small-scale magnetic reconnection on the sun

    CERN Document Server

    Innes, Davina; Huang, YiMin; Bhattacharjee, Amitava

    2015-01-01

    Our understanding of the process of fast reconnection has undergone a dramatic change in the last 10 years driven, in part, by the availability of high-resolution numerical simulations that have consistently demonstrated the break-up of current sheets into magnetic islands, with reconnection rates that become independent of Lundquist number, challenging the belief that fast magnetic reconnection in flares proceeds via the Petschek mechanism that invokes pairs of slow-mode shocks connected to a compact diffusion region. The reconnection sites are too small to be resolved with images but these reconnection mechanisms, Petschek and the plasmoid instability, have reconnection sites with very different density and velocity structures and so can be distinguished by high-resolution line-profiles observations. Using IRIS spectroscopic observations we obtain a survey of typical line profiles produced by small-scale events thought to be reconnection sites on the Sun. Slit-jaw images are used to investigate the plasma h...

  10. Clinical profile of levobupivacaine in regional anesthesia: A systematic review

    Directory of Open Access Journals (Sweden)

    Sukhminder Jit Singh Bajwa

    2013-01-01

    Full Text Available The quest for searching newer and safer anesthetic agents has always been one of the primary needs in anesthesiology practice. Levobupivacaine, the pure S (−-enantiomer of bupivacaine, has strongly emerged as a safer alternative for regional anesthesia than its racemic sibling, bupivacaine. Levobupivacaine has been found to be equally efficacious as bupivacaine, but with a superior pharmacokinetic profile. Clinically, levobupivacaine has been observed to be well-tolerated in regional anesthesia techniques both after bolus administration and continuous post-operative infusion. The incidence of adverse drug reactions (ADRs is rare when it is administered correctly. Most ADRs are related to faulty administration technique (resulting in systemic exposure or pharmacological effects of anesthesia; however, allergic reactions can also occur rarely. The available literary evidence in anesthesia practice indicates that levobupivacaine and bupivacaine produce comparable surgical sensory block, similar adverse side effects and provision of similar labor analgesia with good comparable maternal and fetal outcome. The present review aims to discuss the pharmacokinetic and pharmacological essentials of the safer profile of levobupivacaine as well as to discuss the scope and indications of levobupivacaine based on current clinical evidence.

  11. TIME DEPENDENT NONEQUILIBRIUM IONIZATION OF TRANSITION REGION LINES OBSERVED WITH IRIS

    Energy Technology Data Exchange (ETDEWEB)

    Martínez-Sykora, Juan; Pontieu, Bart De; Hansteen, Viggo H. [Lockheed Martin Solar and Astrophysics Laboratory, Palo Alto, CA 94304 (United States); Gudiksen, Boris, E-mail: j.m.sykora@astro.uio.no [Institute of Theoretical Astrophysics, University of Oslo, P.O. Box 1029 Blindern, NO-0315 Oslo (Norway)

    2016-01-20

    The properties of nonstatistical equilibrium ionization of silicon and oxygen ions are analyzed in this work. We focus on five solar targets (quiet Sun; coronal hole; plage; quiescent active region, AR; and flaring AR) as observed with the Interface Region Imaging Spectrograph (IRIS). IRIS is best suited for this work owing to the high cadence (up to 0.5 s), high spatial resolution (up to 0.″32), and high signal-to-noise ratios for O iv λ1401 and Si iv λ1402. We find that the observed intensity ratio between lines of three times ionized silicon and oxygen ions depends on their total intensity and that this correlation varies depending on the region observed (quiet Sun, coronal holes, plage, or active regions) and on the specific observational objects present (spicules, dynamic loops, jets, microflares, or umbra). In order to interpret the observations, we compare them with synthetic profiles taken from 2D self-consistent radiative MHD simulations of the solar atmosphere, where the statistical equilibrium or nonequilibrium treatment of silicon and oxygen is applied. These synthetic observations show vaguely similar correlations to those in the observations, i.e., between the intensity ratios and their intensities, but only in the nonequilibrium case do we find that (some of) the observations can be reproduced. We conclude that these lines are formed out of statistical equilibrium. We use our time-dependent nonequilibrium ionization simulations to describe the physical mechanisms behind these observed properties.

  12. Measurement the Thermal Profile of Steelmaking Ladle with Subsequent Evaluation the Reasons of Lining Damage

    Directory of Open Access Journals (Sweden)

    Vlček J.

    2016-03-01

    Full Text Available Based on the operational measurement, of which content was to determine ladle thermal profile, there were analysed causes of possible damage of lining in steel ladles by steel breakout through the ladle shell. There exists connection between thermal state of ladle lining during the operation and its lifetime. There were reached to the conclusion that the cause of failure in the lining of ladle is except for high temperature of bath, also wide interval of temperature change during the tap operation, in consequence with possible insufficient pre-heating of ladle, discontinuous operation of aggregate and damage of insulating lining layer, respectively deformation of ladles shell.

  13. Gene expression profiling and gene copy-number changes in malignant mesothelioma cell lines.

    Science.gov (United States)

    Zanazzi, Claudia; Hersmus, Remko; Veltman, Imke M; Gillis, Ad J M; van Drunen, Ellen; Beverloo, H Berna; Hegmans, Joost P J J; Verweij, Marielle; Lambrecht, Bart N; Oosterhuis, J Wolter; Looijenga, Leendert H J

    2007-10-01

    Malignant mesothelioma (MM) is an asbestos-induced tumor that acquires aneuploid DNA content during the tumorigenic process. We used instable MM cell lines as an in vitro model to study the impact of DNA copy-number changes on gene expression profiling, in the course of their chromosomal redistribution process. Two MM cell lines, PMR-MM2 (early passages of in vitro culture) and PMR-MM7 (both early and late passages of in vitro culture), were cytogenetically characterized. Genomic gains and losses were precisely defined using microarray-based comparative genomic hybridization (array-CGH), and minimal overlapping analysis led to the identification of the common unbalanced genomic regions. Using the U133Plus 2.0 Affymetrix gene chip array, we analyzed PMR-MM7 early and late passages for genome-wide gene expression, and correlated the differentially expressed genes with copy-number changes. The presence of a high number of genetic imbalances occurring from early to late culture steps reflected the tendency of MM cells toward genomic instability. The selection of specific chromosomal abnormalities observed during subsequent cultures demonstrated the spontaneous evolution of the cancer cells in an in vitro environment. MM cell lines were characterized by copy-number changes associated with the TP53 apoptotic pathway already present at the first steps of in vitro culture. Prolonged culture led to acquisition of additional chromosomal copy-number changes associated with dysregulation of genes involved in cell adhesion, regulation of mitotic cell cycle, signal transduction, carbohydrate metabolism, motor activity, glycosaminoglycan biosynthesis, protein binding activity, lipid transport, ATP synthesis, and methyltransferase activity.

  14. Molecule survival in magnetized protostellar disk winds. II. Predicted H2O line profiles versus Herschel/HIFI observations

    CERN Document Server

    Yvart, W; Forets, G Pineau des; Ferreira, J

    2016-01-01

    We investigate whether the broad wings of H2O emission identified with Herschel towards low-mass Class 0 and Class 1 protostars may be consistent with an origin in a dusty MHD disk wind, and the constraints it would set on the underlying disk properties. We present synthetic H2O line profiles predictions for a typical MHD disk wind solution with various values of disk accretion rate, stellar mass, extension of the launching area, and view angle. We compare them in terms of line shapes and intensities with the HIFI profiles observed by the WISH Key Program. We find that a dusty MHD disk wind launched from 0.2--0.6 AU AU to 3--25 AU can reproduce to a remarkable degree the observed shapes and intensities of the broad H2O component, both in the fundamental 557 GHz line and in more excited lines. Such a model also readily reproduces the observed correlation of 557 GHz line luminosity with envelope density, if the infall rate at 1000 AU is 1--3 times the disk accretion rate in the wind ejection region. It is also ...

  15. On-line (HPLC-NMR) and off-line phytochemical profiling of the Australian plant, Lasiopetalum macrophyllum.

    Science.gov (United States)

    Timmers, Michael; Urban, Sylvia

    2012-05-01

    On-line (HPLC-NMR) and off-line (HPLC, NMR and MS) methodologies were used to profile the constituents present in the crude extract of Lasiopetalum macrophyllum. On-flow and stop-flow HPLC-NMR supported the presence of trans-tiliroside and permitted partial identification of cis-tiliroside and 4'-methoxy-trans-tiliroside. Off-line isolation led to the unequivocal identification of four flavanoid glycosides including a new structural derivative, 4'-methoxycis-tiliroside. This is the first report of flavonoid glycosides occurring in this plant genus. In addition, a number of structure revisions have been proposed for previously reported flavonoid glycosides that were incorrectly assigned.

  16. Electron density profile measurements from hydrogen line intensity ratio method in Versatile Experiment Spherical Torus

    Science.gov (United States)

    Kim, YooSung; Shi, Yue-Jiang; Yang, Jeong-hun; Kim, SeongCheol; Kim, Young-Gi; Dang, Jeong-Jeung; Yang, Seongmoo; Jo, Jungmin; Oh, Soo-Ghee; Chung, Kyoung-Jae; Hwang, Y. S.

    2016-11-01

    Electron density profiles of versatile experiment spherical torus plasmas are measured by using a hydrogen line intensity ratio method. A fast-frame visible camera with appropriate bandpass filters is used to detect images of Balmer line intensities. The unique optical system makes it possible to take images of Hα and Hβ radiation simultaneously, with only one camera. The frame rate is 1000 fps and the spatial resolution of the system is about 0.5 cm. One-dimensional local emissivity profiles have been obtained from the toroidal line of sight with viewing dumps. An initial result for the electron density profile is presented and is in reasonable agreement with values measured by a triple Langmuir probe.

  17. Height distribution of equipotential lines in a region confined by a rough conducting boundary

    CERN Document Server

    de Castro, C P; de Castilho, C M C; Andrade, R F S

    2014-01-01

    This work considers the behavior of the height distributions of the equipotential lines in a region confined by two interfaces: a cathode with an irregular interface and a distant flat anode. Both boundaries, which are maintained at distinct and constant potential values, are assumed to be conductors. The morphology of the cathode interface results from the deposit of $2 \\times 10^{4}$ monolayers that are produced using a single competitive growth model based on the rules of the Restricted Solid on Solid and Ballistic Deposition models, both of which belong to the Kadar-Parisi-Zhang (KPZ) universality class. At each time step, these rules are selected with probability $p$ and $q = 1 - p$. For several irregular profiles that depend on $p$, a family of equipotential lines is evaluated. The lines are characterized by the skewness and kurtosis of the height distribution. The results indicate that the skewness of the equipotential line increases when they approach the flat anode, and this increase has a non-trivia...

  18. The Fundamental Plane of the Broad-line Region in Active Galactic Nuclei

    CERN Document Server

    Du, Pu; Hu, Chen; Ho, Luis C; Li, Yan-Rong; Bai, Jin-Ming

    2016-01-01

    Broad emission lines in active galactic nuclei (AGNs) mainly arise from gas photoionized by continuum radiation from an accretion disk around a central black hole. The shape of the broad-line profile, described by ${\\cal D}_{_{\\rm H\\beta}}={\\rm FWHM}/\\sigma_{_{\\rm H\\beta}}$, the ratio of full width at half maximum to the dispersion of broad H$\\beta$, reflects the dynamics of the broad-line region (BLR) and correlates with the dimensionless accretion rate ($\\dot{\\mathscr{M}}$) or Eddington ratio ($L_{\\rm bol}/L_{\\rm Edd}$). At the same time, $\\dot{\\mathscr{M}}$ and $L_{\\rm bol}/L_{\\rm Edd}$ correlate with ${\\cal R}_{\\rm Fe}$, the ratio of optical Fe II to H$\\beta$ line flux emission. Assembling all AGNs with reverberation mapping measurements of broad H$\\beta$, both from the literature and from new observations reported here, we find a strong bivariate correlation of the form $\\log(\\dot{\\mathscr{M}},L_{\\rm bol}/L_{\\rm Edd})=\\alpha+\\beta{\\cal D}_{_{\\rm H\\beta}}+\\gamma{\\cal R}_{\\rm Fe},$ where $\\alpha=(2.47,0.31...

  19. Microlensing of the Broad Emission Line Region in the Quadruple Lens SDSS J1004+4112

    CERN Document Server

    Richards, G T; Pindor, B; Hennawi, J F; Hall, P B; Turner, E L; Inada, N; Oguri, M; Ichikawa, S I; Becker, R H; Gregg, M D; White, R L; Wyithe, J S B; Schneider, D P; Johnston, D E; Frieman, J A; Brinkmann, J; Richards, Gordon T.; Keeton, Charles R.; Pindor, Bartosz; Hennawi, Joseph F.; Hall, Patrick B.; Turner, Edwin L.; Inada, Naohisa; Oguri, Masamune; Ichikawa, Shin-Ichi; Becker, Robert H.; Gregg, Michael D.; White, Richard L.; Schneider, Donald P.; Johnston, David E.; Frieman, Joshua A.

    2004-01-01

    We present seven epochs of spectroscopy on the quadruply imaged quasar SDSS J1004+4112, spanning observed-frame time delays from 1 to 322 days. The spectra reveal differences in the emission lines between the lensed images. Specifically, component A showed a strong enhancement in the blue wings of several high-ionization lines relative to component B, which lasted at least 28 days (observed frame) then faded. Since the predicted time delay between A and B is <30 days, our time coverage suggests that the event was not intrinsic to the quasar. We attribute these variations to microlensing of part of the broad emission line region of the quasar, apparently resolving structure in the source plane on a scale of ~10^{16} cm at z=1.734. In addition, we observed smaller differences in the emission line profiles between components A and B that persisted throughout the time span, which may also be due to microlensing or millilensing. Further spectroscopic monitoring of this system holds considerable promise for reso...

  20. Clues to Quasar Broad Line Region Geometry and Kinematics

    DEFF Research Database (Denmark)

    Vestergaard, Marianne; Wilkes, B. J.; Barthel, P. D.

    2000-01-01

    width to show significant inverse correlations with the fractional radio core-flux density, R, the radio axis inclination indicator. Highly inclined systems have broader line wings, consistent with a high-velocity field perpendicular to the radio axis. By contrast, the narrow line-core shows...... and with an accretion disk-wind emitting the broad lines. A spherical distribution of randomly orbiting broad-line clouds and a polar high-ionization outflow are ruled out....

  1. Genome-wide expression profiling of complex regional pain syndrome.

    Directory of Open Access Journals (Sweden)

    Eun-Heui Jin

    Full Text Available Complex regional pain syndrome (CRPS is a chronic, progressive, and devastating pain syndrome characterized by spontaneous pain, hyperalgesia, allodynia, altered skin temperature, and motor dysfunction. Although previous gene expression profiling studies have been conducted in animal pain models, there genome-wide expression profiling in the whole blood of CRPS patients has not been reported yet. Here, we successfully identified certain pain-related genes through genome-wide expression profiling in the blood from CRPS patients. We found that 80 genes were differentially expressed between 4 CRPS patients (2 CRPS I and 2 CRPS II and 5 controls (cut-off value: 1.5-fold change and p<0.05. Most of those genes were associated with signal transduction, developmental processes, cell structure and motility, and immunity and defense. The expression levels of major histocompatibility complex class I A subtype (HLA-A29.1, matrix metalloproteinase 9 (MMP9, alanine aminopeptidase N (ANPEP, l-histidine decarboxylase (HDC, granulocyte colony-stimulating factor 3 receptor (G-CSF3R, and signal transducer and activator of transcription 3 (STAT3 genes selected from the microarray were confirmed in 24 CRPS patients and 18 controls by quantitative reverse transcription-polymerase chain reaction (qRT-PCR. We focused on the MMP9 gene that, by qRT-PCR, showed a statistically significant difference in expression in CRPS patients compared to controls with the highest relative fold change (4.0±1.23 times and p = 1.4×10(-4. The up-regulation of MMP9 gene in the blood may be related to the pain progression in CRPS patients. Our findings, which offer a valuable contribution to the understanding of the differential gene expression in CRPS may help in the understanding of the pathophysiology of CRPS pain progression.

  2. Modelling Chromospheric Line Profiles in NGC2808: Evidence of Mass Loss from RGB Stars

    CERN Document Server

    Mauas, P J D; Pasquini, L

    2006-01-01

    In this study we test the possibility that the asymmetry in the profiles of the H-alpha and Ca II K lines in red giant stars is due to the presence of an active chromosphere rather than to mass loss. To this end, we compare line profiles computed using relevant model chromospheres to profiles of the H-alpha and Ca II K lines observed in five red giant stars of the globular cluster NGC 2808. The spectra were taken with FLAMES during Science Verification, using the UVES mode at high resolution (R=43,000) for the H-alpha line, and GIRAFFE in MEDUSA mode (R=20,000) for the Ca II K line. We find that the observed profiles are better described if a negative (outward) velocity field is included in the model chromospheres. This leads to mass loss rates of a few 10**(-9) solar masses per year, very close to the requirements of the stellar evolution theory.

  3. Clinical profile of hemophilia patients in Jodhpur Region

    Directory of Open Access Journals (Sweden)

    Vikas Payal

    2016-01-01

    Full Text Available Background: Hemophilia is widely distributed all over the world, but little is known about its clinical profile in resource-limited regions. An insight into its clinical spectrum will help in the formulation of policies to improve the situation in these areas. Aims: To study the clinical profile of hemophiliacs (age <18 years in Jodhpur region and screen them for transfusion-transmitted infections. Materials and Methods: A cross-sectional study conducted in the Department of Pediatrics, Umaid Hospital, Dr. S. N. Medical College, Jodhpur, over a period of 12 months. Result: Out of a total of 56 cases enrolled, 51 (91% cases were diagnosed as hemophilia A while 5 (9% were diagnosed as hemophilia B. Positive family history was found in 26 (46% cases. According to their factor levels, 25 (44% cases had severe disease, 20 (36% had moderate disease, and 11 (20% had mild disease. The mean age of onset of symptoms and diagnosis was 1.73 ± 1.43 and 3.87 ± 3.84 years, respectively. First clinical presentation was posttraumatic bleed in 20 (36%, gum bleeds in 17 (30%, epistaxis in 4 (7%, joint bleeds in 4 (7%, skin bleeds in 4 (7%, and circumcision bleed in 3 (5% cases. Knee joint was the predominant joint affected by hemarthrosis in 38 (68%, followed by ankle in 29 (52%, elbow in 20 (36%, and hip joint in 7 (13% cases. All patients had a negative screening test for transfusion-transmitted infections. Conclusion: Occurrence of posttraumatic bleeds and gum bleeds in an otherwise normal child should warn the clinician for evaluation of hemophilia.

  4. Procedure for analyzing the x-ray line profiles of disordered carbons

    Energy Technology Data Exchange (ETDEWEB)

    Henry, L.G.; Bragg, R.H.; Bose, S.

    1981-12-01

    A systematic procedure to correct for various distortions in the broad x-ray line profiles of glass-like carbons (GC) is described. The profile is first corrected for distortions due to low specimen absorption, secondly for incoherent (Compton) scattering, and then strong small angle scattering. The resulting profile is then multiplied by the appropriate trigonometric (Lorentz and polarization) factors. Finally, correction is made for the variation of the atomic scattering factor across the broad peaks. Two examples of the GC heat treatment at 1000/sup 0/C and 2700/sup 0/C have been used to illustrate the outcome of the corrections. 8 figures.

  5. Neon and [CII] 158 micron Emission Line Profiles in Dusty Starbursts and Active Galactic Nuclei

    CERN Document Server

    Samsonyan, Anahit; Lebouteiller, Vianney; Barry, Donald; Sargsyan, Lusine

    2016-01-01

    The sample of 379 extragalactic sources is presented that have mid-infrared, high resolution spectroscopy with the Spitzer Infrared Spectrograph (IRS) and also spectroscopy of the [CII] 158 um line with the Herschel Photodetector Array Camera and Spectrometer (PACS). The emission line profiles of [NeII] 12.81 um, [NeIII] 15.55 um, and [CII] 158 um are presented, and intrinsic line widths are determined (full width half maximum of Gaussian profiles after instrumental correction). All line profiles together with overlays comparing positions of PACS and IRS observations are made available in the Cornell Atlas of Spitzer IRS Sources (CASSIS). Sources are classified from AGN to starburst based on equivalent widths of the 6.2 um polycyclic aromatic hydrocarbon feature. It is found that intrinsic line widths do not change among classification for [CII], with median widths of 207 km per s for AGN, 248 km per s for composites, and 233 km per s for starbursts. The [NeII] line widths also do not change with classificati...

  6. Estimation of Mass-Loss Rates from Emission Line Profiles in the UV Spectra of Cool Stars

    Science.gov (United States)

    Carpenter, K. G.; Robinson, R. D.; Harper, G. M.

    1999-01-01

    The photon-scattering winds of cool, low-gravity stars (K-M giants and supergiants) produce absorption features in the strong chromospheric emission lines. This provides us with an opportunity to assess important parameters of the wind, including flow and turbulent velocities, the optical depth of the wind above the region of photon creation, and the star's mass-loss rate. We have used the Lamers et al. Sobolev with Exact Integration (SEI) radiative transfer code along with simple models of the outer atmospheric structure to compute synthetic line profiles for comparison with the observed line profiles. The SEI code has the advantage of being computationally fast and allows a great number of possible wind models to be examined. We therefore use it here to obtain initial first-order estimates of the wind parameters. More sophisticated, but more time-consuming and resource intensive calculations will be performed at a later date, using the SEI-deduced wind parameters as a starting point. A comparison of the profiles over a range of wind velocity laws, turbulence values, and line opacities allows us to constrain the wind parameters, and to estimate the mass-loss rates. We have applied this analysis technique (using lines of Mg II, 0 I, and Fe II) so far to four stars: the normal K5-giant alpha Tau, the hybrid K-giant gamma Dra, the K5 supergiant lambda Vel, and the M-giant gamma Cru. We present in this paper a description of the technique, including the assumptions which go into its use, an assessment of its robustness, and the results of our analysis.

  7. Pulsational mode-typing in line profile variables. I - Four Beta Cephei stars

    Science.gov (United States)

    Campos, A. J.; Smith, M. A.

    1980-01-01

    The detailed variations of line profiles in the Beta Cephei-type variable stars Gamma Pegasi, Beta Cephei, Delta Ceti and Sigma Scorpii are modeled throughout their pulsation cycles in order to classify the dominant pulsation mode as radial or nonradial. High-dispersion Reticon observations of the variables were obtained for the Si III line at 4567 A, and line profiles broadened by radial or nonradial pulsations, rotation and radial-tangential macroturbulence were calculated based on a model atmosphere. It is found that only a radial pulsation mode can reproduce the radial velocity amplitude, changes in line asymmetry and uniform line width observed in all four stars. Results are in agreement with the color-to-light arguments of Stamford and Watson (1978), and suggest that radial pulsation plays the dominant role in the observed variations in most Beta Cephei stars. Evidence for shocks or moving shells is also found in visual line data for Sigma Scorpii and an ultraviolet line of Beta Cephei, together with evidence of smooth, secular period changes in Beta Cephei and Delta Ceti.

  8. Recommended isolated-line profile for representing high-resolution spectroscopic transitions (IUPAC Technical Report)

    CERN Document Server

    Tennyson, Jonathan; Campargue, Alain; Csaszar, Attila G; Daumont, Ludovic; Gamache, Robert R; Hodges, Joseph T; Lisak, Daniel; Naumenko, Olga V; Rothman, Laurence S; Tran, Ha; Zobov, Nikolai F; Buldyreva, Jeanna; Boone, Chris D; De Vizia, Maria Domenica; Gianfrani, Livio; Hartmann, Jean-Michel; McPheat, Robert; Murray, Jonathan; Ngo, Ngoc Hoa; Polyansky, Oleg L; Weidmann, Damien

    2014-01-01

    The report of an IUPAC Task Group, formed in 2011 on "Intensities and line shapes in high-resolution spectra of water isotopologues from experiment and theory" (Project No. 2011-022-2-100), on line profiles of isolated high-resolution rotational-vibrational transitions perturbed by neutral gas-phase molecules is presented. The well-documented inadequacies of the Voigt profile (VP), used almost universally by databases and radiative-transfer codes, to represent pressure effects and Doppler broadening in isolated vibrational-rotational and pure rotational transitions of the water molecule have resulted in the development of a variety of alternative line-profile models. These models capture more of the physics of the influence of pressure on line shapes but, in general, at the price of greater complexity. The Task Group recommends that the partially Correlated quadratic-Speed-Dependent Hard-Collision profile should be adopted as the appropriate model for high-resolution spectroscopy. For simplicity this should b...

  9. line profile variability in the B8Ia-type supergiant Rigel (β Ori)

    Science.gov (United States)

    Morrison, N. D.; Rother, R.; Kurschat, N.

    2008-04-01

    Hα observations of Rigel obtained on 184 nights during the past ten years with the 1-m telescope and ´echelle spectrograph of Ritter Observatory are surveyed. The line profiles were classified in terms of morphology. About 1/4 of them are of P Cygni type, about 15% inverse P Cygni, about 25% double-peaked, about 1/3 pure absorption, and a few are single emission lines. Transformation of the profile from one type to another typically takes a few days. Although the line stays in absorption for extended intervals, only one high-velocity absorption event of the intensity reported by Kaufer et al. (1996a) was observed, in late 2006. Late in this event, Hα absorption occurred farther to the red than the red wing of a plausible photospheric absorption component, an indication of infalling material. In general, as the absorption events come to an end, the emission typically returns with an inverse P Cygni profile. The Hα profile class shows no obvious correlation with the radial velocity of C II λ6578, a photospheric absorption line.

  10. Distorted cyclotron line profile in Cep X-4 as observed by NuSTAR

    DEFF Research Database (Denmark)

    Fürst, F.; Pottschmidt, K.; Miyasaka, H.;

    2015-01-01

    a powerlaw with a Fermi-Dirac cutoff at high energies. Cep X-4 has a very strong cyclotron resonant scattering feature (CRSF) around 30 keV. A simple absorption-like line with a Gaussian optical depth or a pseudo-Lorentzian profile both fail to describe the shape of the CRSF accurately, leaving significant...

  11. X-ray Emission Line Profiles from Wind Clump Bow Shocks in Massive Stars

    CERN Document Server

    Ignace, R; Cassinelli, J P

    2012-01-01

    The consequences of structured flows continue to be a pressing topic in relating spectral data to physical processes occurring in massive star winds. In a preceding paper, our group reported on hydrodynamic simulations of hypersonic flow past a rigid spherical clump to explore the structure of bow shocks that can form around wind clumps. Here we report on profiles of emission lines that arise from such bow shock morphologies. To compute emission line profiles, we adopt a two component flow structure of wind and clumps using two "beta" velocity laws. While individual bow shocks tend to generate double horned emission line profiles, a group of bow shocks can lead to line profiles with a range of shapes with blueshifted peak emission that depends on the degree of X-ray photoabsorption by the interclump wind medium, the number of clump structures in the flow, and the radial distribution of the clumps. Using the two beta law prescription, the theoretical emission measure and temperature distribution throughout the...

  12. Line printing solution-processable small molecules with uniform surface profile via ink-jet printer.

    Science.gov (United States)

    Liu, Huimin; Xu, Wei; Tan, Wanyi; Zhu, Xuhui; Wang, Jian; Peng, Junbiao; Cao, Yong

    2016-03-01

    Line printing offers a feasible approach to remove the pixel well structure which is widely used to confine the ink-jet printed solution. In the study, a uniform line is printed by an ink-jet printer. To achieve a uniform surface profile of the printed line, 10vol% low-volatile solvent DMA (3,4-Dimethylanisole) is mixed with high-volatile solvent Pxy (p-xylene) as the solvent. After a solution-processable small molecule is dissolved, the surface tension of DMA solution becomes lower than that of Pxy solution, which creates an inward Marangoni flow during the solvent evaporation. The inward Marangoni flow balances out the outward capillary flow, thereby forming a flat film surface. The line width of the printed line depends on the contact angle of the solution on the hole injection layer.

  13. HIGH-VELOCITY LINE FORMING REGIONS IN THE TYPE Ia SUPERNOVA 2009ig

    Energy Technology Data Exchange (ETDEWEB)

    Marion, G. H.; Foley, Ryan J.; Challis, Peter; Kirshner, Robert P. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Vinko, Jozsef; Wheeler, J. Craig; Silverman, Jeffrey M. [University of Texas at Austin, 1 University Station C1400, Austin, TX 78712-0259 (United States); Hsiao, Eric Y. [Carnegie Observatories, Las Campanas Observatory, Colina El Pino, Casilla 601 (Chile); Brown, Peter J. [George P. and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy, Department of Physics and Astronomy, Texas A and M University, 4242 AMU, College Station, TX 77843 (United States); Filippenko, Alexei V. [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Garnavich, Peter [Department of Physics, University of Notre Dame, 225 Nieuwland Science Hall, Notre Dame, IN 46556 (United States); Landsman, Wayne B. [Adnet Systems, NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Parrent, Jerod T. [Las Cumbres Observatory Global Telescope Network, Goleta, CA 93117 (United States); Pritchard, Tyler A.; Roming, Peter W. A. [Department of Astronomy and Astrophysics, Penn State University, 525 Davey Lab, University Park, PA 16802 (United States); Wang, Xiaofeng, E-mail: gmarion@cfa.harvard.edu [Physics Department and Tsinghua Center for Astrophysics (THCA), Tsinghua University, Beijing 1,00084 (China)

    2013-11-01

    We report measurements and analysis of high-velocity (HVF) (>20,000 km s{sup –1}) and photospheric absorption features in a series of spectra of the Type Ia supernova (SN) 2009ig obtained between –14 days and +13 days with respect to the time of maximum B-band luminosity (B-max). We identify lines of Si II, Si III, S II, Ca II, and Fe II that produce both HVF and photospheric-velocity (PVF) absorption features. SN 2009ig is unusual for the large number of lines with detectable HVF in the spectra, but the light-curve parameters correspond to a slightly overluminous but unexceptional SN Ia (M{sub B} = –19.46 mag and Δm{sub 15}(B) = 0.90 mag). Similarly, the Si II λ6355 velocity at the time of B-max is greater than 'normal' for an SN Ia, but it is not extreme (v{sub Si} = 13,400 km s{sup –1}). The –14 days and –13 days spectra clearly resolve HVF from Si II λ6355 as separate absorptions from a detached line forming region. At these very early phases, detached HVF are prevalent in all lines. From –12 days to –6 days, HVF and PVF are detected simultaneously, and the two line forming regions maintain a constant separation of about 8000 km s{sup –1}. After –6 days all absorption features are PVF. The observations of SN 2009ig provide a complete picture of the transition from HVF to PVF. Most SNe Ia show evidence for HVF from multiple lines in spectra obtained before –10 days, and we compare the spectra of SN 2009ig to observations of other SNe. We show that each of the unusual line profiles for Si II λ6355 found in early-time spectra of SNe Ia correlate to a specific phase in a common development sequence from HVF to PVF.

  14. Clues to Quasar Broad Line Region Geometry and Kinematics

    DEFF Research Database (Denmark)

    Vestergaard, Marianne; Wilkes, B. J.; Barthel, P. D.

    2000-01-01

    We present evidence that the high-velocity CIV lambda 1549 emission line gas of radio-loud quasars may originate in a disk-like configuration, in close proximity to the accretion disk often assumed to emit the low-ionization lines. For a sample of 36 radio-loud z~2 quasars we find the 20--30% peak...

  15. Analysis of expression profiles of MAGE-A antigens in oral squamous cell carcinoma cell lines

    Directory of Open Access Journals (Sweden)

    Reichert Torsten E

    2009-04-01

    Full Text Available Abstract Background The immunological response to solid tumours is insufficient. Therefore, tumour specific antigens have been explored to facilitate the activation of the immune system. The cancer/testis antigen class of MAGE-A antigens is a possible target for vaccination. Their differential expression profiles also modulate the course of the cancer disease and its response to antineoplastic drugs. Methods The expression profiles of MAGE-A2, -A3, -A4, -A6 and -A10 in five own oral squamous cell carcinoma cell lines were characterised by rt-PCR, qrt-PCR and immunocytochemistry with a global MAGE-A antibody (57B and compared with those of an adult keratinocyte cell line (NHEK. Results All tumour cell lines expressed MAGE-A antigens. The antigens were expressed in groups with different preferences. The predominant antigens expressed were MAGE-A2, -A3 and -A6. MAGE-A10 was not expressed in the cell lines tested. The MAGE-A gene products detected in the adult keratinocyte cell line NHEK were used as a reference. Conclusion MAGE-A antigens are expressed in oral squamous cell carcinomas. The expression profiles measured facilitate distinct examinations in forthcoming studies on responses to antineoplastic drugs or radiation therapy. MAGE-A antigens are still an interesting aim for immunotherapy.

  16. The extended narrow-line region of two type-I quasi-stellar objects

    CERN Document Server

    Oh, Semyeong; Bennert, Vardha N; Jungwiert, Bruno; Haas, Martin; Leipski, Christian; Albrecht, Marcus

    2013-01-01

    We investigate the narrow-line region (NLR) of two radio-quiet QSOs, PG1012+008 and PG1307+085, using high signal-to-noise spatially resolved long-slit spectra obtained with FORS1 at the Very Large Telescope. Although the emission is dominated by the point-spread function of the nuclear source, we are able to detect extended NLR emission out to several kpc scales in both QSOs by subtracting the scaled central spectrum from outer spectra. In contrast to the nuclear spectrum, which shows a prominent blue wing and a broad line profile of the [O III] line, the extended emission reveals no clear signs of large scale outflows. Exploiting the wide wavelength range, we determine the radial change of the gas properties in the NLR, i.e., gas temperature, density, and ionization parameter, and compare them with those of Seyfert galaxies and type-II QSOs. The QSOs have higher nuclear temperature and lower electron density than Seyferts, but show no significant difference compared to type-II QSOs, while the ionization par...

  17. Eastern Visayas: profile of the region's volunteer outreach worker.

    Science.gov (United States)

    Diaz, C A

    1983-01-01

    Volunteer outreach workers in Eastern Visayas (Region 8) who tend to remain in the Philippine Population Program are able to plan for the welfare of the family, are seriously concerned about the welfare of the community, are traditional in their beliefs about family decision making, are moderately innovative, and are relatively dissatisfied with community life. The research report submitted to the regional office of the Commission on Population (Popcom) by the Regional Research Center for Population, Leyte State College, indicated that Popcom recognizes the importance of community based fieldworkers in the delivery of its services. The study was conducted in line with efforts to improve the system of recruiting volunteer workers and to develop a more effective service delivery scheme. The researchers randomly selected a representative sample of volunteer workers--265 active and 86 inactive--from the provinces of Leyte, Southern Leyte, Eastern Samar, Western Samar and Northern Samar, the subprovince of Biliran, and the cities of Tacloban, Ormoc, and Calbayog. The active volunteer worker of Eastern Visayas is female, between 36-40 years old, married, and the mother of 3-5 children. She also considers the size of her family to be "just right." The volunteer worker believes the father is the prinicipal decision maker in the family and that parents should always be consulted on matters concerning their children. The inactive volunteer worker is also female, in the same age bracket, married, and with 3-5 children, and she also does not want to have additional children. She is more innovative and more receptive to change than the active volunteer worker. She is more satisfied with community life, is modern in her beliefs as to who is the authority in the family, and believes that children also should have a part in making family decisions. Mobility in terms of residence is an important factor in the decision of the volunteer worker to remain in or drop out of the program.

  18. Spectral Line-Shape Model to Replace the Voigt Profile in Spectroscopic Databases

    Science.gov (United States)

    Lisak, Daniel; Ngo, Ngoc Hoa; Tran, Ha; Hartmann, Jean-Michel

    2014-06-01

    The standard description of molecular line shapes in spectral databases and radiative transfer codes is based on the Voigt profile. It is well known that its simplified assumptions of absorber free motion and independence of collisional parameters from absorber velocity lead to systematic errors in analysis of experimental spectra, and retrieval of gas concentration. We demonstrate1,2 that the partially correlated quadratic speed-dependent hardcollision profile3. (pCqSDHCP) is a good candidate to replace the Voigt profile in the next generations of spectroscopic databases. This profile takes into account the following physical effects: the Doppler broadening, the pressure broadening and shifting of the line, the velocity-changing collisions, the speed-dependence of pressure broadening and shifting, and correlations between velocity- and phase/state-changing collisions. The speed-dependence of pressure broadening and shifting is incorporated into the pCqSDNGP in the so-called quadratic approximation. The velocity-changing collisions lead to the Dicke narrowing effect; however in many cases correlations between velocityand phase/state-changing collisions may lead to effective reduction of observed Dicke narrowing. The hard-collision model of velocity-changing collisions is also known as the Nelkin-Ghatak model or Rautian model. Applicability of the pCqSDHCP for different molecular systems was tested on calculated and experimental spectra of such molecules as H2, O2, CO2, H2O in a wide span of pressures. For all considered systems, pCqSDHCP is able to describe molecular spectra at least an order of magnitude better than the Voigt profile with all fitted parameters being linear with pressure. In the most cases pCqSDHCP can reproduce the reference spectra down to 0.2% or better, which fulfills the requirements of the most demanding remote-sensing applications. An important advantage of pCqSDHCP is that a fast algorithm for its computation was developedab4,5 and allows

  19. THE Lyα LINE PROFILES OF ULTRALUMINOUS INFRARED GALAXIES: FAST WINDS AND LYMAN CONTINUUM LEAKAGE

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Crystal L.; Wong, Joseph [Department of Physics, University of California, Santa Barbara, CA, 93106 (United States); Dijkstra, Mark [Institute of Theoretical Astrophysics, University of Oslo, Postboks 1029, 0858 Oslo (Norway); Henry, Alaina [Astrophysics Science Division, Goddard Space Flight Center, Code 665, Greenbelt, MD 20771 (United States); Soto, Kurt T. [Institute for Astronomy, Department of Physics, ETH Zurich, CH-8093 Zurich (Switzerland); Danforth, Charles W., E-mail: cmartin@physics.ucsb.edu [CASA, Department of Astrophysical and Planetary Sciences, University of Colorado, 389-UCB, Boulder, CO, 80309 (United States)

    2015-04-10

    We present new Hubble Space Telescope Cosmic Origins Spectrograph far-ultraviolet (far-UV) spectroscopy and Keck Echellete optical spectroscopy of 11 ultraluminous infrared galaxies (ULIRGs), a rare population of local galaxies experiencing massive gas inflows, extreme starbursts, and prominent outflows. We detect Lyα emission from eight ULIRGs and the companion to IRAS09583+4714. In contrast to the P Cygni profiles often seen in galaxy spectra, the Lyα profiles exhibit prominent, blueshifted emission out to Doppler shifts exceeding −1000 km s{sup −1} in three H ii-dominated and two AGN-dominated ULIRGs. To better understand the role of resonance scattering in shaping the Lyα line profiles, we directly compare them to non-resonant emission lines in optical spectra. We find that the line wings are already present in the intrinsic nebular spectra, and scattering merely enhances the wings relative to the line core. The Lyα attenuation (as measured in the COS aperture) ranges from that of the far-UV continuum to over 100 times more. A simple radiative transfer model suggests the Lyα photons escape through cavities which have low column densities of neutral hydrogen and become optically thin to the Lyman continuum in the most advanced mergers. We show that the properties of the highly blueshifted line wings on the Lyα and optical emission-line profiles are consistent with emission from clumps of gas condensing out of a fast, hot wind. The luminosity of the Lyα emission increases nonlinearly with the ULIRG bolometric luminosity and represents about 0.1–1% of the radiative cooling from the hot winds in the H ii-dominated ULIRGs.

  20. The Lyα Line Profiles of Ultraluminous Infrared Galaxies: Fast Winds and Lyman Continuum Leakage

    Science.gov (United States)

    Martin, Crystal L.; Dijkstra, Mark; Henry, Alaina; Soto, Kurt T.; Danforth, Charles W.; Wong, Joseph

    2015-04-01

    We present new Hubble Space Telescope Cosmic Origins Spectrograph far-ultraviolet (far-UV) spectroscopy and Keck Echellete optical spectroscopy of 11 ultraluminous infrared galaxies (ULIRGs), a rare population of local galaxies experiencing massive gas inflows, extreme starbursts, and prominent outflows. We detect Lyα emission from eight ULIRGs and the companion to IRAS09583+4714. In contrast to the P Cygni profiles often seen in galaxy spectra, the Lyα profiles exhibit prominent, blueshifted emission out to Doppler shifts exceeding -1000 km s-1 in three H ii-dominated and two AGN-dominated ULIRGs. To better understand the role of resonance scattering in shaping the Lyα line profiles, we directly compare them to non-resonant emission lines in optical spectra. We find that the line wings are already present in the intrinsic nebular spectra, and scattering merely enhances the wings relative to the line core. The Lyα attenuation (as measured in the COS aperture) ranges from that of the far-UV continuum to over 100 times more. A simple radiative transfer model suggests the Lyα photons escape through cavities which have low column densities of neutral hydrogen and become optically thin to the Lyman continuum in the most advanced mergers. We show that the properties of the highly blueshifted line wings on the Lyα and optical emission-line profiles are consistent with emission from clumps of gas condensing out of a fast, hot wind. The luminosity of the Lyα emission increases nonlinearly with the ULIRG bolometric luminosity and represents about 0.1-1% of the radiative cooling from the hot winds in the H ii-dominated ULIRGs.

  1. Live image profiling of neural crest lineages in zebrafish transgenic lines.

    Science.gov (United States)

    Kwak, Jina; Park, Ok Kyu; Jung, Yoo Jung; Hwang, Byung Joon; Kwon, Seung-Hae; Kee, Yun

    2013-03-01

    Zebrafish transgenic lines are important experimental tools for lineage tracing and imaging studies. It is crucial to precisely characterize the cell lineages labeled in transgenic lines to understand their limitations and thus properly interpret the data obtained from their use; only then can we confidently select a line appropriate for our particular research objectives. Here we profiled the cell lineages labeled in the closely related neural crest transgenic lines Tg(foxd3:GFP), Tg(sox10:eGFP) and Tg(sox10:mRFP). These fish were crossed to generate embryos, in which foxd3 and sox10 transgenic neural crest labeling could be directly compared at the cellular level using live confocal imaging. We have identified key differences in the cell lineages labeled in each line during early neural crest development and demonstrated that the most anterior cranial neural crest cells initially migrating out of neural tube at the level of forebrain and anterior midbrain express sox10:eGFP and sox10:mRFP, but not foxd3:GFP. This differential profile was robustly maintained in the differentiating progeny of the neural crest lineages until 3.5dpf. Our data will enable researchers to make an informed choice in selecting transgenic lines for future neural crest research.

  2. Metabolic profiling of breast cancer: Differences in central metabolism between subtypes of breast cancer cell lines.

    Science.gov (United States)

    Willmann, Lucas; Schlimpert, Manuel; Halbach, Sebastian; Erbes, Thalia; Stickeler, Elmar; Kammerer, Bernd

    2015-09-01

    Although the concept of aerobic glycolysis in cancer was already reported in the 1930s by Otto Warburg, the understanding of metabolic pathways remains challenging especially due to the heterogeneity of cancer. In consideration of four different time points (1, 2, 4, and 7 days of incubation), GC-MS profiling of metabolites was performed on cell extracts and supernatants of breast cancer cell lines (MDA-MB-231, -453, BT-474) with different sub classification and the breast epithelial cell line MCF-10A. To the exclusion of trypsinization, direct methanolic extraction, cell scraping and cell disruption was executed to obtain central metabolites. Major differences in biochemical pathways have been observed in the breast cancer cell lines compared to the breast epithelial cell line, as well as between the breast cancer cell lines themselves. Characteristics of breast cancer subtypes could be correlated to their individual metabolic profiles. PLS-DA revealed the discrimination of breast cancer cell lines from MCF-10A based on elevated amino acid levels. The observed metabolic signatures have great potential as biomarker for breast cancer as well as an improved understanding of subtype specific phenomenons of breast cancer.

  3. Long regional magnetotelluric profile crossing geotectonic structures of central Poland

    Science.gov (United States)

    Stefaniuk, M.; Pokorski, J.; Wojdyla, M.

    2009-04-01

    Introduction The magnetotelluric survey was made along a regional profile, which runs across Poland from south-west to north-east during 2005-2006 years. The profile crosses major geological structures of Central Poland, including the Variscan Externides and Variscan foredeep, the Transeuropean Suture Zone and the marginal zone of East European Craton. The main objectives of the project include identification of sub-Zechstein sedimentary structures and evaluation of resistivity distribution within the deep crust, especially at the contact of East European Precambrian Craton and Central Europe Paleozoic structures. The length of the profile is about 700 km; 161 deep magnetotelluric sounding sites were made with a medium spacing of about 4 km. Data acquisition and processing The recording of the components of natural electromagnetic field was made with a broad range of frequencies, varying from 0.0003 Hz up to 575 Hz with use of MT-1 system of Electromagnetic Instruments Incorporation. This frequency band allowed obtaining the information about geology ranging from a few dozen meters to approximately 100 km, depending on the vertical distribution of the resistivity inside geological medium. To reduce the electromagnetic noise, magnetic and electric remote reference was applied. A remote reference site was located at a distance of over 100 km of field sites. Processing of the recorded data included the estimation of the components of impedance tensor (Zxx, Zxy, Zyx and Zyy ), with use of robust type procedures. The components of the impedance tensor allowed in a subsequent step for calculation of field curves for two orientations of the measurement system (XY - described further as the TM mode and YX - TE mode) and additional parameters of the medium like skew, strike, pole diagrams etc. Recording of the vertical component of electromagnetic field (Hz) allowed calculation of tipper parameter T. Magnetotelluric soundings interpretation Geophysical interpretation of MT

  4. Thermonuclear Supernovae: Probing Magnetic Fields by Late-Time IR Line Profiles

    CERN Document Server

    Penney, R

    2014-01-01

    We study the imprint of magnetic fields B on late-time IR line profiles and light curves of Type Ia Supernovae. As a benchmark, we use the explosion of a Chandrasekhar mass M_{Ch White Dwarf (WD) and, specifically, a delayed detonation model. We assume WDs with initial magnetic surface fields between 1 and 1E9G. We discuss large-scale dipole and small-scale magnetic fields. We find that the [Fe II] line at 1.644 mu can be used to analyze the overall chemical and density structure of the exploding WD up to day 200 without considering B. Subsequently, positron transport and magnetic field effects become important. By day 500, the profile becomes sensitive to the morphology of B and directional dependent for dipole fields. Small or no directional dependence of the spectra is found for small-scale B. After about 200 days, persistent broad-line, flat-topped or stumpy profiles require high density burning which is the signature of a WD close to M_Ch. Narrow peaked profiles are a signature of chemical mixing or sub-...

  5. Study of H-alpha Spicule Profiles with Line Inversion Techniques

    Science.gov (United States)

    Tziotziou, K.; Kontogiannis, I.; Tsiropoula, G.; Kotrc, P.

    2008-09-01

    High resolution optical spectra of chromospheric spicules obtained in the H? line are studied together with slit-jaw filtergrams. The spectra were recorded along a vertical slit parallel to the solar limb with the HSFA2 (Horizontal-Sonnen-Forschungs-Anlage) Solar Spectrograph at Ondrejov Observatory on August 19, 2007 and show H? line profiles taken in spicules - due to the limb curvature - at different heights from the solar limb. A multi-cloud model that considers two or more spicules along the line-of-sight (LOS), together with a statistical approach that takes into account a large set of initial conditions for solving the radiative transfer equation, is used for the fitting of the observed profiles and the derivation of several parameters such as the LOS velocity, the source function, the optical thickness and the Doppler width that describe the respective spicules. The height-dependence of the shape of the observed profiles, as well as their dependence on the values of the derived parameters are studied in detail. The derived results are compared with the statistical theoretical results of a multi-cloud model where the aforementioned physical parameters, as well as a random number of spicules along the LOS were taken into account, in order to define the dependence of several spicule profile characteristics on them. Specific steps of the used procedures, as well as crucial problems are discussed.

  6. Effects of Magnetic Coupling on Profile of Emission Lines and Images of an Accretion Disc Around a Black Hole

    Institute of Scientific and Technical Information of China (English)

    MA Ren-Yi; WANG Ding-Xiong; LEI Wei-Hua; YAO Guo-Zheng

    2004-01-01

    @@ The profiles of emission lines and images of an accretion disc around a black hole (BH) are simulated by considering the effects of the magnetic coupling (MC) of a central BH with the disc. The MC effects are discussed for both slow- and fast-spinning BHs, and the following results are obtained. Firstly, the width of the emission lines and the brightness of the disc are reduced and augmented for slow- and fast-spinning BHs, respectively. Secondly,the image of the disc becomes dimmer and brighter near the inner edge of the disc for slow- and fast-spinning BHs, respectively. It turns out that all these results arise from the MC effects on the position of the dominant emission region of the accretion disc.

  7. The LyAlpha Line Profiles of Ultraluminous Infrared Galaxies: Fast Winds and Lyman Continuum Leakage

    CERN Document Server

    Martin, Crystal L; Henry, Alaina; Soto, Kurt T; Danforth, Charles W; Wong, Joseph

    2015-01-01

    We present new Hubble Space Telescope Cosmic Origins Spectrograph far-ultraviolet (far-UV) spectroscopy and Keck Echellete optical spectroscopy of 11 ultraluminous infrared galaxies (ULIRGs), a rare population of local galaxies experiencing massive gas inflows, extreme starbursts, and prominent outflows. We detect H Lyman alpha emission from 8 ULIRGs and the companion to IRAS09583+4714. In contrast to the P Cygni profiles often seen in galaxy spectra, the H Lyman alpha profiles exhibit prominent, blueshifted emission out to Doppler shifts exceeding -1000 km/s in three HII-dominated and two AGN-dominated ULIRGs. To better understand the role of resonance scattering in shaping the H Lyman alpha line profiles, we directly compare them to non-resonant emission lines in optical spectra. We find that the line wings are already present in the intrinsic nebular spectra, and scattering merely enhances the wings relative to the line core. The H Lyman alpha attenuation (as measured in the COS aperture) ranges from that ...

  8. Oncogenic mutation profiling in new lung cancer and mesothelioma cell lines

    Directory of Open Access Journals (Sweden)

    Lam DC

    2015-01-01

    Full Text Available David CL Lam,1 Susan Y Luo,1 Wen Deng,2 Johnny SH Kwan,3 Jaime Rodriguez-Canales,4 Annie LM Cheung,5 Grace HW Cheng,6 Chi-Ho Lin,6 Ignacio I Wistuba,4 Pak C Sham,6 Thomas SK Wan,7 Sai-Wah Tsao5 1Department of Medicine, 2School of Nursing, 3Department of Psychiatry, University of Hong Kong, Hong Kong SAR, People’s Republic of China; 4Department of Translational Molecular Pathology, MD Anderson Cancer Center, University of Texas at Houston, Houston, TX, USA; 5Department of Anatomy, 6Center for Genome Sciences, 7Department of Pathology, University of Hong Kong, Hong Kong SAR, People’s Republic of China Background: Thoracic tumor, especially lung cancer, ranks as the top cancer mortality in most parts of the world. Lung adenocarcinoma is the predominant subtype and there is increasing knowledge on therapeutic molecular targets, namely EGFR, ALK, KRAS, and ROS1, among lung cancers. Lung cancer cell lines established with known clinical characteristics and molecular profiling of oncogenic targets like ALK or KRAS could be useful tools for understanding the biology of known molecular targets as well as for drug testing and screening. Materials and methods: Five new cancer cell lines were established from pleural fluid or biopsy tissues obtained from Chinese patients with primary lung adenocarcinomas or malignant pleural mesothelioma. They were characterized by immunohistochemistry, growth kinetics, tests for tumorigenicity, EGFR and KRAS gene mutations, ALK gene rearrangement and OncoSeq mutation profiling. Results: These newly established lung adenocarcinoma and mesothelioma cell lines were maintained for over 100 passages and demonstrated morphological and immunohistochemical features as well as growth kinetics of tumor cell lines. One of these new cell lines bears EML4-ALK rearrangement variant 2, two lung cancer cell lines bear different KRAS mutations at codon 12, and known single nucleotide polymorphism variants were identified in these cell

  9. Ultraviolet and Optical Line Profile Variations in the Spectrum of ɛ Persei

    Science.gov (United States)

    Gies, D. R.; Kambe, E.; Josephs, T. S.; Bagnuolo, W. G., Jr.; Choi, Y. J.; Gudehus, D.; Guyton, K. M.; Hartkopf, W. I.; Hildebrand, J. L.; Kaye, A. B.; Mason, B. D.; Riddle, R. L.; Sowers, J. W.; Turner, N. H.; Wilson, J. W.; Xiong, Y.

    1999-11-01

    The rapid variable star, ɛ Per (B0.5 IV-III), displays the largest amplitude profile fluctuations known among the growing number of massive, spectrum-variable stars. Here we present an analysis of a continuous 5 day run of IUE UV spectroscopy, and we show for the first time that the systematic, blue-to-red moving patterns observed in high-quality optical spectra are also present in the UV photospheric lines. We present cross-correlation functions of the individual spectra with that of a narrow-lined standard that produce a high signal-to-noise ratio representation of the blue-to-red moving bump patterns found in individual lines. We then use time series analysis methods to determine the periodic components of the profile variations (after reregistering the spectra to correct for binary motion). There are at least six periods present (ranging from 8.46 to 2.27 hr), and most of these signals are also found in optical line variations observed in 1986 (although the relative amplitudes have changed significantly). Furthermore, analysis of a shorter time series of IUE spectra from 1984 shows that similar periods were present then. We also present Hα and He I λ6678 profiles obtained with the Georgia State University Multi-Telescope Telescope, which were made simultaneously with IUE, and we show that the profile variations are essentially identical in the UV and optical ranges. We rule out rotational modulation and circumstellar gas obscuration as possible causes, and we suggest instead that the variations are the result of photospheric nonradial pulsations of relatively low degree (l=3-5). There were significant changes (~10%) in the equivalent widths of the UV stellar wind lines during the IUE run, and we suggest that wind strengthening events are related to episodes of large-amplitude, constructive interference between the NRP modes. Thus, intermode beating may play an important role in promoting wind loss from massive stars.

  10. Searching double-peaked emission line profiles in the spectra of galaxies through the symmetry of the cross-correlation function

    CERN Document Server

    Garcia-Lorenzo, B

    2012-01-01

    The presence of double-peaked/multicomponent emission line profiles in spectra of galaxies is commonly done by visual inspection. However, the identification of complex emission line profiles by eye is unapproachable for large databases such as the Sloan Digital Sky Survey (SDSS) or the integral field spectroscopy surveys of galaxies (e.g. CALIFA or MaNGA). We describe a quick method involving the cross-correlation technique for detecting the presence of complex (double-peaked or multiple components) profiles in the spectra of galaxies, deriving simultaneously a first estimation of the velocity dispersions and radial velocities of the dominant gaseous component. We illustrate the proposed procedure with the well-known complex [OIII]4959,5007 profiles of the central region of NGC1068.

  11. Lipoprotein profiles of hepatic cell lines at various stages of differentiation.

    Science.gov (United States)

    Sasaki, Akira; Kimura, Fumiko; Miura, Mizuho; Toshima, Gen; Takahashi, Junichiro; Maruya, Sayuri; Kobayashi, Masayuki; Hata, Keishi

    2017-02-01

    We studied the lipoprotein profiles of human hepatic cells at various stages of differentiation. The production of three major classes of lipoproteins, very low-density lipoprotein (VLDL), low-density lipoprotein (LDL), and high-density lipoprotein (HDL), was detected in three well-differentiated human hepatoma cell lines and primary human hepatocytes; however, these lipoproteins were not detected in the culture medium in which undifferentiated hepatoma cell lines were grown. Reverse transcription polymerase chain reaction analysis demonstrated that the expression levels of apolipoprotein A1 (ApoA1), ApoB100, and microsomal triglyceride transfer protein (MTP) were markedly lower in the undifferentiated hepatoma cell lines than in the well-differentiated hepatoma cell lines and primary hepatocytes. These results indicate that apolipoprotein synthesis, and triglyceride-transport by MTP might be rate-limiting steps in lipoprotein production in mature hepatic cells.

  12. Genomic and phenotypic profiles of two Brazilian breast cancer cell lines derived from primary human tumors

    DEFF Research Database (Denmark)

    Corrêa, Natássia C R; Kuasne, Hellen; Faria, Jerusa A Q A

    2013-01-01

    Breast cancer is the most common type of cancer among women worldwide. Research using breast cancer cell lines derived from primary tumors may provide valuable additional knowledge regarding this type of cancer. Therefore, the aim of this study was to investigate the phenotypic profiles of MACL-1...... and MGSO-3, the only Brazilian breast cancer cell lines available for comparative studies. We evaluated the presence of hormone receptors, proliferation, differentiation and stem cell markers, using immunohistochemical staining of the primary tumor, cultured cells and xenografts implanted....... This shift in expression may be due to the selection of an 'establishment' phenotype in vitro. Whole-genome DNA evaluation showed a large amount of copy number alterations (CNAs) in the two cell lines. These findings render MACL-1 and MGSO-3 the first characterized Brazilian breast cancer cell lines...

  13. Expression profile of hypothalamic neuropeptides in chicken lines selected for high or low residual feed intake.

    Science.gov (United States)

    Sintubin, P; Greene, E; Collin, A; Bordas, A; Zerjal, T; Tesseraud, S; Buyse, J; Dridi, S

    2014-08-01

    The R(+) and R(-) chicken lines have been divergently selected for high (R(+)) or low (R(-)) residual feed intake. For the same body weight and egg production, the R(+) chickens consume 40% more food than their counterparts R(-) lines. In the present study we sought to determine the hypothalamic expression profile of feeding-related neuropeptides in these lines maintained under fed or food-deprived conditions. In the fed condition, the suppressor of cytokine signaling 3 (SOCS3) was 17-fold lower (Pfeeding-related genes that are differently expressed in the hypothalamus of R(+) and R(-) chickens and that might explain the difference in feed intake observed between the two lines. Published by Elsevier Ltd.

  14. Solar Transition-Region Lines Observed by the Interface Region Imaging Spectrograph: Diagnostics for the O IV and Si IV Lines

    CERN Document Server

    Dudík, Jaroslav; Dzifčáková, Elena; Mason, Helen E; Golub, Leon

    2013-01-01

    The formation of the transition-region O IV and Si IV lines observable by the Interface Region Imaging Spectrograph (IRIS) is investigated for both Maxwellian and non-Maxellian conditions characterized by a kappa-distribution exhibiting a high-energy tail. The \\ion{Si}{4} lines are formed at lower temperatures than the O IV lines for all kappa. In non-Maxwellian situations with lower kappa, the contribution functions are shifted to lower temperatures. Combined with the slope of the differential emission measure, it is possible for the Si IV lines to be formed at very different regions of solar transition region than the O IV lines; possibly close to solar chromosphere. Such situations might be discernible by IRIS. It is found that photoexcitation can be important for the Si IV lines, but is negligible for the O IV lines. The usefulness of the O IV ratios for density diagnostics independently of kappa is investigated and it is found that the O IV 1404.78A /1399.77A ratio provides a good density diagnostics exc...

  15. Structural characterization of lead sulfide thin films by means of X-ray line profile analysis

    Indian Academy of Sciences (India)

    N Choudhury; B K Sarma

    2009-02-01

    X-ray diffraction patterns of chemically deposited lead sulphide thin films have been recorded and X-ray line profile analysis studies have been carried out. The lattice parameter, crystallite size, average internal stress and microstrain in the film are calculated and correlated with molarities of the solutions. Both size and strain are found to contribute towards the broadening of X-ray diffraction line. The values of the crystallite size are found to be within the range from 22–33 nm and the values of strain to be within the range from 1.0 × 10-3–2.5 × 10-3.

  16. Gene expression profiling in chemoresistant variants of three cell lines of different origin

    DEFF Research Database (Denmark)

    Johnsson, Anders; Vallon-Christensson, Johan; Strand, Carina

    2005-01-01

    BACKGROUND: Drug resistance is a major problem in clinical cancer chemotherapy. Several mechanisms of resistance have been identified, but the underlying genomic changes are still poorly understood. MATERIALS AND METHODS: Gene expression profiling, using cDNA microarray, was performed in eight cell....... Several genes encoding ABC transporters were highly up-regulated, most notably ABCB1 (MDR1) and ABCB4 in several cell lines and ABCG2 (MXR) specifically in MX-resistant cell lines. A pronounced down-regulation of several histones was noted in the MCF-7-derived resistant sublines. Altered expression...

  17. Detailed Characterization of H_beta emission line profile in low z SDSS quasars

    OpenAIRE

    Zamfir, S.; Sulentic, J. W.; Marziani, P; D. Dultzin

    2009-01-01

    We explore the properties of the H_beta emission line profile in a large, homogeneous and bright sample of N~470 low redshift quasars extracted from Sloan Digital Sky Survey (DR5). We approach the investigation from two complementary directions: composite/median spectra and a set of line diagnostic measures (asymmetry index, centroid shift and kurtosis) in individual quasars. The project is developed and presented in the framework of the so-called 4D Eigenvector 1 (4DE1) Parameter Space, with...

  18. Overweight and obesity profiles in Niger Delta Region, Nigeria

    Directory of Open Access Journals (Sweden)

    Alphhonsus U. Idung

    2014-01-01

    Full Text Available Introduction: Overweight and obesity are global public health problems because of their effect on individuals, families and communities. The objective of this study was to describe the profile of overweight and obesity amongst adult out patients in Uyo in the Niger Delta region of Nigeria.Method: This was a cross-sectional descriptive study done between October 2011 and March 2012. Using a systematic sampling technique, 584 subjects aged 18–65 years were recruited; data were collected with a structured questionnaire. Subjects were measured for height, weight, waist and hip circumferences. Body mass index (BMI and waist–hip ratio (WHR were calculated. Subjects with a BMI of 25.0 kg/m2 – 29.9 kg/m2 were regarded as being overweight whilst a BMI of > 30.0 kg/m2 was regarded as obese. Subjects with a WHR of > 0.90 for men or > 0.85 for women were regarded as having abnormal WHR.Results: Of the 584 subjects, 196 (36.6% were men and 388 (66.4% women. The mean age for men and women was 43.3 ± 17.8 years and 50.2 ± 13.6 years, respectively. The prevalence of overweight amongst men was 39.8% versus 31.7% for women; obesity in men was 28.0% versus 52.0% in women. Overweight and obesity were more prevalent in subjects aged 25–54 years and amongst married subjects. There was a significant relationship between obesity and television viewing (p = 0.003. Hypertension (p = 0.008 and osteoarthropathies (p = 0.043 were more prevalent amongst the obese than the non-obese subjects.Conclusion: Overweight and obesity are now common in our environment. There is therefore a need for more public education about the health consequences of big body size.

  19. Correlations between different line-forming regions in quasar environments

    Science.gov (United States)

    Chen, Chen; Hamann, Fred; Lundgren, Britt

    2017-01-01

    The early stage of massive galaxy evolution can involve outflows driven by a starburst or a central quasar plus cold mode accretion (infall) adding to the mass build-up in the galaxies. We are using SDSS-BOSS DR12 database to study the nature of infall and outflows in quasar environments by examining the relationships of their narrow absorption lines (NALs) at positive and negative velocity shifts to other quasar properties such as their broad absorption line (BAL) outflows, emission line characteristics, radio-loudness, and reddening by dust. We also test for extreme high-velocity NAL outflows (with speeds 0.1-0.2c) based on relationships to low-speed NALs and quasar properties, and we perform detailed analyses of particular cases of rich multi-component NAL complexes that might result from high-speed quasar outflows shredding and dispersing interstellar clouds in the host galaxies. Our results show that low-velocity NALs and rich NAL complexes correlate strongly with BALs, suggesting a physical relationship. Infalling systems are less common in quasars with BALs, suggesting that BAL outflows can halt or disrupt gas accretion. The extreme high-velocity NALs (at 0.1-0.2c) show a weak relationship to BALs and a strong dependence on low-velocity NALs, indicating that a significant fraction of these systems is ejected from the quasars (and are *not* unrelated intervening clouds). We find no correlations between radio flux and low-velocity NALs, infalling systems, or rich complexes, which indicates that none of these features are closely tied to quasar radio properties. We analyze the relationship of the N V/C IV line strengths (a possible abundance/metallicity probe) in emission versus absorption lines and find no correlation between them.

  20. Interpreting the Mg II h and k Line Profiles of Mira Variables

    CERN Document Server

    Wood, B E; Wood, Brian E.; Karovska, Margarita

    2000-01-01

    We use radiative transfer calculations to reproduce the basic appearance of Mg II lines observed from Mira variables. These lines have centroids that are blueshifted by at least 30 km/s from the stellar rest frame. It is unlikely that flow velocities in the stellar atmospheres are this fast, so radiative transfer effects must be responsible for this behavior. Published hydrodynamic models predict the existence of cool, downflowing material above the shocked material responsible for the Mg II emission, and we demonstrate that scattering in this layer can result in Mg II profiles as highly blueshifted as those that are observed. However, our models also show that scattering within the shock plays an equally strong role in shaping the Mg II profiles, and our calculations illustrate the importance of partial redistribution and the effects of being out of ionization equilibrium.

  1. Fundamental Parameter Method Applied to X-Ray Line Profile Analysis

    OpenAIRE

    Florica Matei; Nicolae Aldea; Marius Rada; Ioana Pop

    2016-01-01

    Crystallite size strain effect the mechanical, electric, magnetic and optical properties of many kind of the nanomaterials. The effects of the finite crystallite size and lattice strain can be very well observed as the deformation in the shape of the X-ray line profile (XRLP). In this contribution we have used the fundamental parameter (FP) [1,2] method to evaluate the nanostructure materials assuming a theoretical model of experimental XRLP.  In this contribution we have used various distrib...

  2. A study of the Lyman-$\\alpha$ line profile in DBA white dwarfs

    CERN Document Server

    Genest-Beaulieu, C

    2016-01-01

    The hydrogen abundances in DBA white dwarfs determined from optical or UV spectra have been reported to differ significantly in some studies. We revisit this problem using our own model atmospheres and synthetic spectra, and present a theoretical investigation of the Lyman-$\\alpha$ line profile as a function of effective temperature and hydrogen abundance. We identify one possible solution to this discrepancy and show considerable improvement from a detailed analysis of optical and UV spectra of DBA stars.

  3. X-ray narrow emission lines from the nuclear region of NGC 1365

    CERN Document Server

    Whewell, M; Page, M J

    2016-01-01

    NGC 1365 is a Seyfert 2 galaxy with a starburst ring in its nuclear region. In this work we look at the XMM Reflection Grating Spectrometer (RGS) data from four 2012-13, three 2007 and two 2004 observations of NGC 1365. We characterise the narrow-line emitting gas visible by XMM RGS and make comparisons between the 2012-13 spectra and those from 2004-07, already published. This source is usually absorbed within the soft X-ray band, with a typical neutral column density of >1.5 x 10$^{23}$ cm$^{-2}$, and only 1 observation of the 9 we investigate shows low enough absorption for the continuum to emerge in the soft X-rays. We stack all observations from 2004-07, and separately three of the four observations from 2012-13, analysing the less absorbed observation separately. We first model the spectra using gaussian profiles representing the narrow line emission. We fit physically motivated models to the 2012-13 stacked spectra, with collisionally ionised components representing the starburst emission and photoioni...

  4. Reprocessed emission line profiles from dense clouds in geometrically thick accretion engines

    CERN Document Server

    Hartnoll, S A; Hartnoll, Sean A.

    2000-01-01

    The central engines of active galactic nuclei (AGN) contain cold, dense material as well as hot X-ray emitting gas. The standard paradigm for the engine geometry is a cold thin disc sandwiched between hot X-ray coronae. Strong support for this geometry in Seyferts comes from the study of fluorescent iron line profiles, although the evidence is not ubiquitously air tight. The thin disc model of line profiles in AGN and in X-ray binaries should be bench marked against other plausible possibilities. One proposed alternative is an engine consisting of dense clouds embedded in an optically thin, geometrically thick X-ray emitting engine. This model is further motivated by studies of geometrically thick engines such as advection dominated accretion flows (ADAFs). Here we compute the reprocessed iron line profiles from dense clouds embedded in geometrically thick, optically thin X-ray emitting discs near a Schwarzchild black hole. We consider a range of cloud distributions and disc solutions, including ADAFs, pure r...

  5. Detection method of proximal caries using line profile in digital intra-oral radiography

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yong Suk; Kim, Gyu Tae; Hwang, Eui Hwan; Lee, Min Ja; Choi, Sam Jin; Park, Hun Kuk [Department of Oral and Maxillofacial Radiology, School of Dentistry and Institute of Oral Biology, Kyung Hee University, Seoul (Korea, Republic of); Park, Jeong Hoon [Department of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul (Korea, Republic of)

    2009-12-15

    The purpose of this study was to investigate how to detect proximal caries using line profile and validate linear measurements of proximal caries lesions by basic digital manipulation of radiographic images. The X-ray images of control group (15) and caries teeth (15) from patients were used. For each image, the line profile at the proximal caries-susceptible zone was calculated. To evaluate the contrast as a function of line profile to detect proximal caries, a difference coefficient (D) that indicates the relative difference between caries and sound dentin or intact enamel was measured. Mean values of D were 0.0354 {+-} 0.0155 in non-caries and 0.2632 {+-} 0.0982 in caries (p<0.001). The mean values of caries group were higher than non-caries group and there was correlation between proximal dental caries and D. It is demonstrated that the mean value of D from caries group was higher than that of control group. From the result, values of D possess great potentiality as a new detection parameter for proximal dental caries.

  6. Fourier-Doppler Imaging of Line Profile Variations in ζ Ophiuchi

    Science.gov (United States)

    Jankov, S.; Janot-Pacheco, E.; Leister, N. V.

    2000-09-01

    We present, for the first time, the Fourier-Doppler Imaging (FDI) analysis of periodic line profile variations in a ζ Oph-type star. For this purpose we obtained, in the period from 1996 May 3 to May 5, a total of 242 high-resolution, high signal-to-noise ratio spectra of the Be star ζ Oph itself. Using the FDI technique, we examine the variations in both time and wavelength and complement it with time series analysis. This kind of analysis is valid for both the nonradial pulsator model and the rotation modulation model, but we discuss the results in terms of the former model, considering it the more likely explanation for the observed line profile variability. Two distinct groups of modes are detected: medium (4high-degree modes (which could be associated with 13high-frequency oscillations were strongly confined to an equatorial belt narrower than 20° and that the line profile variability was caused predominantly by sectoral modes, although tesseral modes |m|=l-1 are not excluded in taking into account the effect of fast rotation. We discuss the modal nature of the waves with respect to the characteristic oscillation periods in the corotating frame and the high amplitude of the projected rotational velocity variations (~20 km s-1).

  7. Distinctive characteristics of transcriptional profiles from two epithelial cell lines upon interaction with Actinobacillus actinomycetemcomitans.

    Science.gov (United States)

    Mans, J J; Baker, H V; Oda, D; Lamont, R J; Handfield, M

    2006-08-01

    Transcriptional profiling and gene ontology analyses were performed to investigate the unique responses of two different epithelial cell lines to an Actinobacillus actinomycetemcomitans challenge. A total of 2867 genes were differentially regulated among all experimental conditions. The analysis of these 2867 genes revealed that the predominant specific response to infection in HeLa cells was associated with the regulation of enzyme activity, RNA metabolism, nucleoside and nucleic acid transport and protein modification. The predominant specific response in immortalized human gingival keratinocytes (IHGK) was associated with the regulation of angiogenesis, chemotaxis, transmembrane receptor protein tyrosine kinase signaling, cell differentiation, apoptosis and response to stress. Of particular interest, stress response genes were significantly - yet differently - affected in both cell lines. In HeLa cells, only three regulated genes impacted the response to stress, and the response to unfolded protein was the only term that passed the ontology filters. This strikingly contrasted with the profiles obtained for IHGK, in which 61 regulated genes impacted the response to stress and constituted an extensive network of cell responses to A. actinomycetemcomitans interaction (response to pathogens, oxidative stress, unfolded proteins, DNA damage, starvation and wounding). Hence, while extensive similarities were found in the transcriptional profiles of these two epithelial cell lines, significant differences were highlighted. These differences were predominantly found in pathways that are associated with host-pathogen interactions.

  8. Method for measuring radial impurity emission profiles using correlations of line integrated signals

    Science.gov (United States)

    Kuldkepp, M.; Brunsell, P. R.; Drake, J.; Menmuir, S.; Rachlew, E.

    2006-04-01

    A method of determining radial impurity emission profiles is outlined. The method uses correlations between line integrated signals and is based on the assumption of cylindrically symmetric fluctuations. Measurements at the reversed field pinch EXTRAP T2R show that emission from impurities expected to be close to the edge is clearly different in raw as well as analyzed data to impurities expected to be more central. Best fitting of experimental data to simulated correlation coefficients yields emission profiles that are remarkably close to emission profiles determined using more conventional techniques. The radial extension of the fluctuations is small enough for the method to be used and bandpass filtered signals indicate that fluctuations below 10kHz are cylindrically symmetric. The novel method is not sensitive to vessel window attenuation or wall reflections and can therefore complement the standard methods in the impurity emission reconstruction procedure.

  9. Temporal Variation of Ca–K Line Profile of the Sun during the Solar Cycle 22 and 23

    Indian Academy of Sciences (India)

    G. Sindhuja; Jagdev Singh

    2015-03-01

    We obtained the Ca–K line profile of the Sun as a star since 1969 at the Kodaikanal Observatory (KO) and analysis of the data showed the need to delineate the role of different chromospheric features to the variations of solar irradiance. We, therefore, initiated a new methodology to make observations of Ca–K line profiles of the Sun as a function of latitude and integrated over the longitude on a daily basis since 1986. We have collected the data for about thousand days, spread over two solar cycles. Earlier data (before 1997) were recorded on the photographic film and later data using the CCD detector. The photographic film data were digitized and analysed along with the data obtained from CCD camera. From these data, we computed K1 and K2 widths for the Sun as a star, using all the observed line profiles as a function of latitude. In addition, we have analyzed the spectra of the whole Sun as a star obtained on some days and compared it with the results obtained from latitude spectra of the same day. The K1 and K2 widths of the Sun as a star derived from the KO data are compared with values determined from the observations made at other observatories to compare results from the new methodology of observations adopted by us and the earlier techniques. The average values of K1 width during the minimum period. of solar cycle 23 are smaller than those during the minimum period of cycle 22. Day-to-day variations in the K1 and K2 widths and plage areas may imply that irradiance variations occur not only due to large-scale solar activity, but also because of variations in some of the three types of network in quiet regions of the Sun. The variation in intensity of the plages can also cause day-to-day variations in widths.

  10. Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

    Directory of Open Access Journals (Sweden)

    James Campbell

    2016-03-01

    Full Text Available One approach to identifying cancer-specific vulnerabilities and therapeutic targets is to profile genetic dependencies in cancer cell lines. Here, we describe data from a series of siRNA screens that identify the kinase genetic dependencies in 117 cancer cell lines from ten cancer types. By integrating the siRNA screen data with molecular profiling data, including exome sequencing data, we show how vulnerabilities/genetic dependencies that are associated with mutations in specific cancer driver genes can be identified. By integrating additional data sets into this analysis, including protein-protein interaction data, we also demonstrate that the genetic dependencies associated with many cancer driver genes form dense connections on functional interaction networks. We demonstrate the utility of this resource by using it to predict the drug sensitivity of genetically or histologically defined subsets of tumor cell lines, including an increased sensitivity of osteosarcoma cell lines to FGFR inhibitors and SMAD4 mutant tumor cells to mitotic inhibitors.

  11. The implementation of non-Voigt line profiles in the HITRAN database: H2 case study

    Science.gov (United States)

    Wcisło, P.; Gordon, I. E.; Tran, H.; Tan, Y.; Hu, S.-M.; Campargue, A.; Kassi, S.; Romanini, D.; Hill, C.; Kochanov, R. V.; Rothman, L. S.

    2016-07-01

    Experimental capabilities of molecular spectroscopy and its applications nowadays require a sub-percent or even sub-per mille accuracy of the representation of the shapes of molecular transitions. This implies the necessity of using more advanced line-shape models which are characterized by many more parameters than a simple Voigt profile. It is a great challenge for modern molecular spectral databases to store and maintain the extended set of line-shape parameters as well as their temperature dependences. It is even more challenging to reliably retrieve these parameters from experimental spectra over a large range of pressures and temperatures. In this paper we address this problem starting from the case of the H2 molecule for which the non-Voigt line-shape effects are exceptionally pronounced. For this purpose we reanalyzed the experimental data reported in the literature. In particular, we performed detailed line-shape analysis of high-quality spectra obtained with cavity-enhanced techniques. We also report the first high-quality cavity-enhanced measurement of the H2 fundamental vibrational mode. We develop a correction to the Hartmann-Tran profile (HTP) which adjusts the HTP to the particular model of the velocity-changing collisions. This allows the measured spectra to be better represented over a wide range of pressures. The problem of storing the HTP parameters in the HITRAN database together with their temperature dependences is also discussed.

  12. Generation and gene expression profiling of 48 transcription-factor-inducible mouse embryonic stem cell lines

    Science.gov (United States)

    Yamamizu, Kohei; Sharov, Alexei A.; Piao, Yulan; Amano, Misa; Yu, Hong; Nishiyama, Akira; Dudekula, Dawood B.; Schlessinger, David; Ko, Minoru S. H.

    2016-01-01

    Mouse embryonic stem cells (ESCs) can differentiate into a wide range – and possibly all cell types in vitro, and thus provide an ideal platform to study systematically the action of transcription factors (TFs) in cell differentiation. Previously, we have generated and analyzed 137 TF-inducible mouse ESC lines. As an extension of this “NIA Mouse ESC Bank,” we generated and characterized 48 additional mouse ESC lines, in which single TFs in each line could be induced in a doxycycline-controllable manner. Together, with the previous ESC lines, the bank now comprises 185 TF-manipulable ESC lines (>10% of all mouse TFs). Global gene expression (transcriptome) profiling revealed that the induction of individual TFs in mouse ESCs for 48 hours shifts their transcriptomes toward specific differentiation fates (e.g., neural lineages by Myt1 Isl1, and St18; mesodermal lineages by Pitx1, Pitx2, Barhl2, and Lmx1a; white blood cells by Myb, Etv2, and Tbx6, and ovary by Pitx1, Pitx2, and Dmrtc2). These data also provide and lists of inferred target genes of each TF and possible functions of these TFs. The results demonstrate the utility of mouse ESC lines and their transcriptome data for understanding the mechanism of cell differentiation and the function of TFs. PMID:27150017

  13. Doppler ghosts in a hall of mirrors polarisation profiles of scattered emission lines

    CERN Document Server

    Henney, W J

    1994-01-01

    The Doppler shifts of optical emission lines which have been scattered by surrounding dust and electrons can provide useful information about the kinematics, geometry and physical conditions of astrophysical flows. In principle, the scatterers can provide views of the line-emitting gas from different directions, allowing the 3-d velocity field of the emitting gas to be determined and revealing sources which are hidden from direct view. Unfortunately, as in a Hall of Mirrors, the resultant multiple images can be confusing and hard to interpret. In general, the scattering geometry will be unknown, which makes it difficult to disentangle the effect of the motion of the scatterers from that of the motion of the emitting source. In this situation, spectropolarimetric observations can be a great help, since the scattered light will be partially polarised to a degree dependent on the angle of scattering and on the details of the scattering process. Analysis of the polarisation profiles of the scattered emission line...

  14. Emission lines from rotating proto-stellar jets with variable velocity profiles. I. Three-dimensional numerical simulation of the non-magnetic case

    CERN Document Server

    Cerqueira, A H; Raga, A C; Vasconcelos, M J; De Colle, F

    2005-01-01

    Using the Yguazu-a three-dimensional hydrodynamic code, we have computed a set of numerical simulations of heavy, supersonic, radiatively cooling jets including variabilities in both the ejection direction (precession) and the jet velocity (intermittence). In order to investigate the effects of jet rotation on the shape of the line profiles, we also introduce an initial toroidal rotation velocity profile, in agreement with some recent observational evidence found in jets from T Tauri stars which seems to support the presence of a rotation velocity pattern inside the jet beam, near the jet production region. Since the Yguazu-a code includes an atomic/ionic network, we are able to compute the emission coefficients for several emission lines, and we generate line profiles for the H, [O I]6300, [S II]6716 and [N II]6548 lines. Using initial parameters that are suitable for the DG Tau microjet, we show that the computed radial velocity shift for the medium-velocity component of the line profile as a function of di...

  15. Solar Flare Termination Shock and Synthetic Emission Line Profiles of the Fe xxi 1354.08 Å Line

    Science.gov (United States)

    Guo, Lijia; Li, Gang; Reeves, Kathy; Raymond, John

    2017-09-01

    Solar flares are among the most energetic phenomena that occur in the solar system. In the standard solar flare model, a fast mode shock, often referred to as the flare termination shock (TS), can exist above the loop-top source of hard X-ray emissions. The existence of the TS has been recently related to spectral hardening of a flare’s hard X-ray spectra at energies >300 keV. Observations of the Fe xxi 1354.08 Å line during solar flares by the Interface Region Imaging Spectrograph (IRIS) spacecraft have found significant redshifts with >100 km s‑1, which is consistent with a reconnection downflow. The ability to detect such a redshift with IRIS suggests that one may be able to use IRIS observations to identify flare TSs. Using a magnetohydrodynamic simulation to model magnetic reconnection of a solar flare and assuming the existence of a TS in the downflow of the reconnection plasma, we model the synthetic emission of the Fe xxi 1354.08 line in this work. We show that the existence of the TS in the solar flare may manifest itself in the Fe xxi 1354.08 Å line.

  16. NUMERICAL SIMULATIONS OF THE EMISSION-LINE REGIONS OF QUASARS

    Institute of Scientific and Technical Information of China (English)

    Gary J.Ferland

    2001-01-01

    The luninous quasars are the most distant objects we can directly observe. Once understood, their emission lines will measure the quasar's luminosity and the composition of the interstellar medium of the host galaxy. Unfortunately the emitting plasma is far from equilibrium, and its conditions are set by a host of microphysical processes. The equations of statistical and thermal equilibrium must be solved to determine the ionization distribution, level populations, and kinetic temperature as a function of depth. Simultaneously the line and continuum radiative transfer problems are solved to predict the observed spectrum.A complete simulation involves many hundreds of stages of ionization, many thousands of levels, with populations determined by a vast sea of atomic and molecular processes, many with accurate cross sections and rate coefficients only now becoming available. This is a problem at the very forefront of atomic and computational physics. Once complete, we will be able to map out the first generations of stellar processing in the cores of massive galaxies, and directly chart the expansion of the universe when it had an age under a billion years.

  17. Molecular line tracers of high-mass star forming regions

    NARCIS (Netherlands)

    Nagy, Zsofia; Van der Tak, Floris; Ossenkopf, Volker; Bergin, Edwin; Black, John; Faure, Alexandre; Fuller, Gary; Gerin, Maryvonne; Goicoechea, Javier; Joblin, Christine; Le Bourlot, Jacques; Le Petit, Franck; Makai, Zoltan; Plume, Rene; Roellig, Markus; Spaans, Marco; Tolls, Volker

    2013-01-01

    High-mass stars influence their environment in different ways including feedback via their FUV radiation. The penetration of FUV photons into molecular clouds creates Photon Dominated Regions (PDRs) with different chemical layers where the mainly ionized medium changes into mainly molecular. Differe

  18. Prospection of genomic regions divergently selected in racing line of Quarter Horses in relation to cutting line.

    Science.gov (United States)

    Meira, C T; Curi, R A; Farah, M M; de Oliveira, H N; Béltran, N A R; Silva, J A V; Mota, M D S da

    2014-11-01

    Selection of Quarter Horses for different purposes has led to the formation of lines, including racing and cutting horses. The objective of this study was to identify genomic regions divergently selected in racing line of Quarter Horses in relation to cutting line applying relative extended haplotype homozygosity (REHH) analysis, an extension of extended haplotype homozygosity (EHH) analysis, and the fixation index (F ST) statistic. A total of 188 horses of both sexes, born between 1985 and 2009 and registered at the Brazilian Association of Quarter Horse Breeders, including 120 of the racing line and 68 of the cutting line, were genotyped using single nucleotide polymorphism arrays. On the basis of 27 genomic regions identified as selection signatures by REHH and F ST statistics, functional annotations of genes were made in order to identify those that could have been important during formation of the racing line and that could be used subsequently for the development of selection tools. Genes involved in muscle growth (n=8), skeletal growth (n=10), muscle energy metabolism (n=15), cardiovascular system (n=14) and nervous system (n=23) were identified, including the FKTN, INSR, GYS1, CLCN1, MYLK, SYK, ANG, CNTFR and HTR2B.

  19. On the use of the Fourier Transform to determine the projected rotational velocity of line-profile variable B stars

    CERN Document Server

    Aerts, C; Groot, P J; Degroote, P

    2014-01-01

    The Fourier Transform method is a popular tool to derive the rotational velocities of stars from their spectral line profiles. However, its domain of validity does not include line-profile variables with time-dependent profiles. We investigate the performance of the method for such cases, by interpreting the line-profile variations of spotted B stars, and of pulsating B tars, as if their spectral lines were caused by uniform surface rotation along with macroturbulence. We perform time-series analysis and harmonic least-squares fitting of various line diagnostics and of the outcome of several implementations of the Fourier Transform method. We find that the projected rotational velocities derived from the Fourier Transform vary appreciably during the pulsation cycle whenever the pulsational and rotational velocity fields are of similar magnitude. The macroturbulent velocities derived while ignoring the pulsations can vary with tens of km/s during the pulsation cycle. The temporal behaviour of the deduced rotat...

  20. A Revised Broad-line Region Radius and Black Hole Mass for the Narrow-line Seyfert 1 NGC 4051

    DEFF Research Database (Denmark)

    Denney, K. D.; Watson, L. C.; Peterson, B. M.

    2009-01-01

    measurements for several relatively low luminosity active galactic nuclei (AGNs). We feature results for NGC 4051 here because, until now, this object has been a significant outlier from AGN scaling relationships, e.g., it was previously a ~2-3s outlier on the relationship between the broad-line region (BLR...

  1. The Fine Structure Lines of Hydrogen in HII Regions

    CERN Document Server

    Dennison, B; Minter, A H; Dennison, Brian; Minter, Anthony H.

    2005-01-01

    The 2s_{1/2} state of hydrogen is metastable and overpopulated in HII regions. In addition, the 2p states may be pumped by ambient Lyman-alpha radiation. Fine structure transitions between these states may be observable in HII regions at 1.1 GHz (2s_{1/2}-2p_{1/2}) and/or 9.9 GHz (2s_{1/2}-2p_{3/2}), although the details of absorption versus emission are determined by the relative populations of the 2s and 2p states. The n=2 level populations are solved with a parameterization that allows for Lyman-alpha pumping of the 2p states. The density of Lyman-alpha photons is set by their creation rate, easily determined from the recombination rate, and their removal rate. Here we suggest that the dominant removal mechanism of Lyman-alpha radiation in HII regions is absorption by dust. This circumvents the need to solve the Lyman-alpha transfer problem, and provides an upper limit to the rate at which the 2p states are populated by Lyman-alpha photons. In virtually all cases of interest, the 2p states are predominantl...

  2. Ultraviolet and Optical Line Profile Variations in the Spectrum of {epsilon} Persei

    Energy Technology Data Exchange (ETDEWEB)

    Gies, D. R.; Kambe, E.; Josephs, T. S.; Bagnuolo, W. G. Jr.; Choi, Y. J.; Gudehus, D.; Guyton, K. M.; Hartkopf, W. I.; Hildebrand, J. L.; Kaye, A. B. (and others)

    1999-11-01

    The rapid variable star, {epsilon} Per (B0.5 IV-III), displays the largest amplitude profile fluctuations known among the growing number of massive, spectrum-variable stars. Here we present an analysis of a continuous 5 day run of IUE UV spectroscopy, and we show for the first time that the systematic, blue-to-red moving patterns observed in high-quality optical spectra are also present in the UV photospheric lines. We present cross-correlation functions of the individual spectra with that of a narrow-lined standard that produce a high signal-to-noise ratio representation of the blue-to-red moving bump patterns found in individual lines. We then use time series analysis methods to determine the periodic components of the profile variations (after reregistering the spectra to correct for binary motion). There are at least six periods present (ranging from 8.46 to 2.27 hr), and most of these signals are also found in optical line variations observed in 1986 (although the relative amplitudes have changed significantly). Furthermore, analysis of a shorter time series of IUE spectra from 1984 shows that similar periods were present then. We also present H{alpha} and He i {lambda}6678 profiles obtained with the Georgia State University Multi-Telescope Telescope, which were made simultaneously with IUE, and we show that the profile variations are essentially identical in the UV and optical ranges. We rule out rotational modulation and circumstellar gas obscuration as possible causes, and we suggest instead that the variations are the result of photospheric nonradial pulsations of relatively low degree (l=3-5). There were significant changes ({approx}10%) in the equivalent widths of the UV stellar wind lines during the IUE run, and we suggest that wind strengthening events are related to episodes of large-amplitude, constructive interference between the NRP modes. Thus, intermode beating may play an important role in promoting wind loss from massive stars. (c) (c) 1999

  3. Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression.

    Directory of Open Access Journals (Sweden)

    Byungwoo Ryu

    Full Text Available BACKGROUND: Gene expression profiling has revolutionized our ability to molecularly classify primary human tumors and significantly enhanced the development of novel tumor markers and therapies; however, progress in the diagnosis and treatment of melanoma over the past 3 decades has been limited, and there is currently no approved therapy that significantly extends lifespan in patients with advanced disease. Profiling studies of melanoma to date have been inconsistent due to the heterogeneous nature of this malignancy and the limited availability of informative tissue specimens from early stages of disease. METHODOLOGY/PRINCIPLE FINDINGS: In order to gain an improved understanding of the molecular basis of melanoma progression, we have compared gene expression profiles from a series of melanoma cell lines representing discrete stages of malignant progression that recapitulate critical characteristics of the primary lesions from which they were derived. Here we describe the unsupervised hierarchical clustering of profiling data from melanoma cell lines and melanocytes. This clustering identifies two distinctive molecular subclasses of melanoma segregating aggressive metastatic tumor cell lines from less-aggressive primary tumor cell lines. Further analysis of expression signatures associated with melanoma progression using functional annotations categorized these transcripts into three classes of genes: 1 Upregulation of activators of cell cycle progression, DNA replication and repair (CDCA2, NCAPH, NCAPG, NCAPG2, PBK, NUSAP1, BIRC5, ESCO2, HELLS, MELK, GINS1, GINS4, RAD54L, TYMS, and DHFR, 2 Loss of genes associated with cellular adhesion and melanocyte differentiation (CDH3, CDH1, c-KIT, PAX3, CITED1/MSG-1, TYR, MELANA, MC1R, and OCA2, 3 Upregulation of genes associated with resistance to apoptosis (BIRC5/survivin. While these broad classes of transcripts have previously been implicated in the progression of melanoma and other malignancies, the

  4. Assessment of a systematic expression profiling approach in ENU-induced mouse mutant lines.

    Science.gov (United States)

    Seltmann, Matthias; Horsch, Marion; Drobyshev, Alexei; Chen, Yali; de Angelis, Martin Hrabé; Beckers, Johannes

    2005-01-01

    Comparative genomewide expression profiling is a powerful tool in the effort to annotate the mouse genome with biological function. The systematic analysis of RNA expression data of mouse lines from the Munich ENU mutagenesis screen might support the understanding of the molecular biology of such mutants and provide new insights into mammalian gene function. In a direct comparison of DNA microarray experiments of individual versus pooled RNA samples of organs from ENU-induced mouse mutants, we provide evidence that individual RNA samples may outperform pools in some aspects. Genes with high biological variability in their expression levels (noisy genes) are identified as false positives in pooled samples. Evidence suggests that highly stringent housing conditions and standardized procedures for the isolation of organs significantly reduce biological variability in gene expression profiling experiments. Data on wild-type individuals demonstrate the positive effect of controlling variables such as social status, food intake before organ sampling, and stress with regard to reproducibility of gene expression patterns. Analyses of several organs from various ENU-induced mutant lines in general show low numbers of differentially expressed genes. We demonstrate the feasibility to detect transcriptionally affected organs employing RNA expression profiling as a tool for molecular phenotyping.

  5. BEYOND THE STANDARD MODEL OF THE DISC–LINE SPECTRAL PROFILES FROM BLACK HOLE ACCRETION DISCS

    Directory of Open Access Journals (Sweden)

    Vjaceslav Sochora

    2014-08-01

    Full Text Available The strong gravitational field of a black hole has distinct effects on the observed profile of a spectral line from an accretion disc near a black hole. The observed profile of the spectral line is broadened and skewed by a fast orbital motion and redshifted by a gravitational field. These effects can help us to constrain the parameters of a system with a black hole, both in active galactic nuclei and in a stellar-mass black hole. Here we explore the fact that an accretion disc emission can be mathematically imagined as a superposition of radiating accretion rings that extend from the inner edge to the outer rim of the disc, with some radially varying emissivity. In our work, we show that a characteristic double-horn profile of several radially confined (relatively narrow accretion rings or belts could be recognized by the planned instruments onboard future satellites (such as the proposed ESA Large Observatory for X-ray Timing.

  6. Line-profile variations in radial-velocity measurements: Two alternative indicators for planetary searches

    CERN Document Server

    Figueira, P; Pepe, F; Lovis, C; Nardetto, N

    2013-01-01

    Aims. We introduce two methods to identify false-positive planetary signals in the context of radial-velocity exoplanet searches. The first is the bi-Gaussian cross-correlation function fitting, and the second is the measurement of asymmetry in radial-velocity spectral line information content, Vasy. Methods. We make a systematic analysis of the most used common line profile diagnosis, Bisector Inverse Slope and Velocity Span, along with the two proposed ones. We evaluate all these diagnosis methods following a set of well-defined common criteria and using both simulated and real data. We apply them to simulated cross-correlation functions created with the program SOAP and which are affected by the presence of stellar spots, and to real cross-correlation functions, calculated from HARPS spectra, for stars with a signal originating both in activity and created by a planet. Results. We demonstrate that the bi-Gaussian method allows a more precise characterization of the deformation of line profiles than the sta...

  7. Hodgkin Lymphoma Cell Lines Are Characterized by a Specific miRNA Expression Profile

    Directory of Open Access Journals (Sweden)

    Johan H. Gibcus

    2009-02-01

    Full Text Available Hodgkin lymphoma (HL is derived from preapoptotic germinal center B cells, although a general loss of B cell phenotype is noted. Using quantitative reverse transcription-polymerase chain reaction and miRNA microarray, we determined the microRNA (miRNA profile of HL and compared this with the profile of a panel of B-cell non-Hodgkin lymphomas. The two methods showed a strong correlation for the detection of miRNA expression levels. The HL-specific miRNA included miR-17-92 cluster members, miR-16, miR-21, miR-24, and miR-155. Using a large panel of cell lines, we found differential expression between HL and other B-cell lymphoma-derived cell lines for 27 miRNA. A significant down-regulation in HL compared to non-Hodgkin lymphoma was observed only for miR-150. Next, we performed target gene validation of predicted target genes for miR-155, which is highly expressed in HL and is differentially expressed between HL and Burkitt lymphoma. Using luciferase reporter assays, we validated 11 predicted miR-155 target genes in three different HL cell lines. We demonstrated that AGTR1, FGF7, ZNF537, ZIC3, and IKBKE are true miR-155 target genes in HL.

  8. Regional anaesthesia and analgesia on the front line.

    Science.gov (United States)

    Scott, D M

    2009-11-01

    Deployment to a combat zone with the military poses many challenges to the anaesthetist. One of these challenges is the safe, rapid and comfortable initial wound management and repatriation of wounded combat soldiers to their home country or tertiary treatment facility for definitive care and rehabilitation. The current conflict in Afghanistan is associated with injury patterns that differ from wars such as Vietnam or Korea. This report describes the experience of an Australian military anaesthetist and the value of regional anaesthesia and analgesia for the care of the wounded combat soldier

  9. Transcriptome Profiling Reveals Degree of Variability in Induced Pluripotent Stem Cell Lines: Impact for Human Disease Modeling.

    Science.gov (United States)

    Schuster, Jens; Halvardson, Jonatan; Pilar Lorenzo, Laureanne; Ameur, Adam; Sobol, Maria; Raykova, Doroteya; Annerén, Göran; Feuk, Lars; Dahl, Niklas

    2015-10-01

    Induced pluripotent stem cell (iPSC) technology has become an important tool for disease modeling. Insufficient data on the variability among iPSC lines derived from a single somatic parental cell line have in practice led to generation and analysis of several, usually three, iPSC sister lines from each parental cell line. We established iPSC lines from a human fibroblast line (HDF-K1) and used transcriptome sequencing to investigate the variation among three sister lines (iPSC-K1A, B, and C). For comparison, we analyzed the transcriptome of an iPSC line (iPSC-K5B) derived from a different fibroblast line (HDF-K5), a human embryonic stem cell (ESC) line (ESC-HS181), as well as the two parental fibroblast lines. All iPSC lines fulfilled stringent criteria for pluripotency. In an unbiased cluster analysis, all stem cell lines (four iPSCs and one ESC) clustered together as opposed to the parental fibroblasts. The transcriptome profiles of the three iPSC sister lines were indistinguishable from each other, and functional pathway analysis did not reveal any significant hits. In contrast, the expression profiles of the ESC line and the iPSC-K5B line were distinct from that of the sister lines iPSC-K1A, B, and C. Differentiation to embryoid bodies and subsequent analysis of germ layer markers in the five stem cell clones confirmed that the distribution of their expression profiles was retained. Taken together, our observations stress the importance of using iPSCs of different parental origin rather than several sister iPSC lines to distinguish disease-associated mechanisms from genetic background effects in disease modeling.

  10. The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression

    DEFF Research Database (Denmark)

    Kenny, Paraic A; Lee, Genee Y; Myers, Connie A;

    2007-01-01

    large scale comparison of the transcriptional profiles and 3D cell culture phenotypes of a substantial panel of human breast cancer cell lines. Each cell line adopts a colony morphology of one of four main classes in 3D culture. These morphologies reflect, at least in part, the underlying gene...... expression profile and protein expression patterns of the cell lines, and distinct morphologies were also associated with tumor cell invasiveness and with cell lines originating from metastases. We further demonstrate that consistent differences in genes encoding signal transduction proteins emerge when even...

  11. Performance comparison of digital microRNA profiling technologies applied on human breast cancer cell lines.

    Directory of Open Access Journals (Sweden)

    Erik Knutsen

    Full Text Available MicroRNA profiling represents an important first-step in deducting individual RNA-based regulatory function in a cell, tissue, or at a specific developmental stage. Currently there are several different platforms to choose from in order to make the initial miRNA profiles. In this study we investigate recently developed digital microRNA high-throughput technologies. Four different platforms were compared including next generation SOLiD ligation sequencing and Illumina HiSeq sequencing, hybridization-based NanoString nCounter, and miRCURY locked nucleic acid RT-qPCR. For all four technologies, full microRNA profiles were generated from human cell lines that represent noninvasive and invasive tumorigenic breast cancer. This study reports the correlation between platforms, as well as a more extensive analysis of the accuracy and sensitivity of data generated when using different platforms and important consideration when verifying results by the use of additional technologies. We found all the platforms to be highly capable for microRNA analysis. Furthermore, the two NGS platforms and RT-qPCR all have equally high sensitivity, and the fold change accuracy is independent of individual miRNA concentration for NGS and RT-qPCR. Based on these findings we propose new guidelines and considerations when performing microRNA profiling.

  12. Gene expression profiles of human promyelocytic leukemia cell lines exposed to volatile organic compounds.

    Science.gov (United States)

    Sarma, Sailendra Nath; Kim, Youn-Jung; Ryu, Jae-Chun

    2010-05-27

    Benzene, toluene, o-xylene, ethylbenzene, trichloroethylene and dichloromethane are the most widely used volatile organic compounds (VOCs), and their toxic mechanisms are still undefined. This study analyzed the genome-wide expression profiles of human promyelocytic leukemia HL-60 cells exposed to VOCs using a 35-K whole human genome oligonucleotide microarray to ascertain potential biomarkers. Genes with a significantly increased expression levels (over 1.5-fold and p-values p53 signaling pathway, apoptosis, and natural killer cell-mediated cytotoxicity pathway. Functionally important immune response- and apoptosis-related genes were further validated by real-time RT-PCR. The results showed that IFIT1, IFIT2, IFIT3, USP18, INFGR2, PMAIP1, GADD45A, NFKBIA, TNFAIP3, and BIRC3 genes altered their expression profiles in a dose-dependent manner. Similar expressions profiles were also found in human erythromyeloblastoid leukemia K562 cells and in human leukemic monocyte lymphoma U937 cells. In conclusion, both gene expression profiles and gene ontology analysis have elucidated potential gene-based biomarkers and provided insights into the mechanism underlying the response of human leukemia cell lines to VOC exposure.

  13. Performance comparison of digital microRNA profiling technologies applied on human breast cancer cell lines.

    Science.gov (United States)

    Knutsen, Erik; Fiskaa, Tonje; Ursvik, Anita; Jørgensen, Tor Erik; Perander, Maria; Lund, Eiliv; Seternes, Ole Morten; Johansen, Steinar D; Andreassen, Morten

    2013-01-01

    MicroRNA profiling represents an important first-step in deducting individual RNA-based regulatory function in a cell, tissue, or at a specific developmental stage. Currently there are several different platforms to choose from in order to make the initial miRNA profiles. In this study we investigate recently developed digital microRNA high-throughput technologies. Four different platforms were compared including next generation SOLiD ligation sequencing and Illumina HiSeq sequencing, hybridization-based NanoString nCounter, and miRCURY locked nucleic acid RT-qPCR. For all four technologies, full microRNA profiles were generated from human cell lines that represent noninvasive and invasive tumorigenic breast cancer. This study reports the correlation between platforms, as well as a more extensive analysis of the accuracy and sensitivity of data generated when using different platforms and important consideration when verifying results by the use of additional technologies. We found all the platforms to be highly capable for microRNA analysis. Furthermore, the two NGS platforms and RT-qPCR all have equally high sensitivity, and the fold change accuracy is independent of individual miRNA concentration for NGS and RT-qPCR. Based on these findings we propose new guidelines and considerations when performing microRNA profiling.

  14. Geometric design and simulation of tooth profile using elliptical segments as its line of action

    Institute of Scientific and Technical Information of China (English)

    王建; 罗善明; 苏德瑜; 常雪峰

    2015-01-01

    A mathematical model of gear tooth profiles using the ellipse curve, whose curvature is convenient to control by changing the mathematical parameters as its line of action, was built based on the meshing theory. The equation of undercutting condition was derived from the model. A special epicycloidal tooth profile was also presented. An example gear drive with variation of the ellipse parameters was taken to illustrate the proposed method. The contact ratio of the gear drive designed by the proposed method was analyzed. A comparison of the property of the gear drive designed with the involute gear drive was also carried out. The results confirm that the proposed gear drive has higher contact ratio in comparison with the involute gear drive.

  15. Profiles of the Regional Educational Laboratories, 1999-2000.

    Science.gov (United States)

    Spencer, Lynn M.; Stonehill, Robert M.

    This handbook describes the mission of each of the 10 Regional Educational Laboratories in the U.S. The laboratories ensure that those involved in educational improvement at the local, state, and regional levels have access to the best available information from research and practice, thus guaranteeing that lessons about school reform that are…

  16. Profiles of the Regional Educational Laboratories, 1997-1998.

    Science.gov (United States)

    Stonehill, Robert M.; Spencer, Lynn M.

    The Regional Educational Laboratory Program is the U.S. Department of Education's largest research-and-development investment designed to help educators, policy makers, and communities improve schools. Administered by the Office of Educational Research and Improvement (OERI), the network of 10 regional labs works to ensure that lessons about…

  17. PROFILES AND PREFERENCES OF ON-LINE MILLENIAL SHOPPERS IN BULGARIA

    Directory of Open Access Journals (Sweden)

    Patricia R. Loubeau

    2014-05-01

    Full Text Available This research seeks to develop a better understanding of the factors affecting on-line purchasing behavior among Generation Y (Gen Y consumers in Bulgaria. Also called millenials and born between the mid-1970s and late 1990s, this generation is especially active on-line and will be a dominant influence shaping e-commerce. An empirical study was conducted based on a written survey of a sample consisting of 367 high school and university students in Bulgaria. The most important reason why Bulgarian young people shop on-line is the pursuit of unique products not locally available, followed by convenience and better pricing, and their favorite category of internet purchases is “Apparel and Accessories.” Bulgarian millennials are using the internet to shop for trendy fashion and to obtain a variety of brands that are unavailable locally. Like other regions of the world, concern about financial transactions security is a major barrier limiting the willingness to shop on-line in Bulgaria. Unlike other markets where on-line music purchases are growing, high levels of digital piracy in Bulgaria strongly discourage Bulgarian students from purchasing music on-line. One limitation of this study arises because of its reliance on a convenience sample of students from medium sized cities in Southern Bulgaria. Further research employing stratified random sampling across Bulgaria is needed to assess whether the findings are broadly generalizable for the Gen Y population.

  18. Line Emission from Radiation-Pressurized HII Region II: Dynamics and Population Synthesis

    CERN Document Server

    Verdolini, Silvia; Krumholz, Mark R; Matzner, Christopher D; Tielens, Alexander G G M

    2013-01-01

    Optical and infrared emission lines from HII regions are an important diagnostic used to study galaxies, but interpretation of these lines requires significant modeling of both the internal structure and dynamical evolution of the emitting regions. Most of the models in common use today assume that HII region dynamics are dominated by the expansion of stellar wind bubbles, and have neglected the contribution of radiation pressure to the dynamics, and in some cases also to the internal structure. However, recent observations of nearby galaxies suggest that neither assumption is justified, motivating us to revisit the question of how HII region line emission depends on the physics of winds and radiation pressure. In a companion paper we construct models of single HII regions including and excluding radiation pressure and winds, and in this paper we describe a population synthesis code that uses these models to simulate galactic collections of HII regions with varying physical parameters. We show that the choice...

  19. Gene expression profile of colon cancer cell lines treated with SN-38

    DEFF Research Database (Denmark)

    Wallin, A; Francis, P; Nilbert, M

    2010-01-01

    Colorectal cancer is the third most common form of cancer in the industrial countries. Due to advances regarding the treatments, primarily development of improved surgical methods and the ability to make the earlier diagnosis, the mortality has remained constant during the past decades even though...... the incidence in fact has increased. To improve chemotherapy and enable personalised treatment, the need of biomarkers is of great significance. In this study, we evaluated the gene expression profiles of the colon cancer cell lines treated with SN-38, the active metabolite of topoisomerase-1 inhibitor...

  20. Gene expression profile of colon cancer cell lines treated with SN-38

    DEFF Research Database (Denmark)

    Wallin, A; Francis, P; Nilbert, M;

    2010-01-01

    the incidence in fact has increased. To improve chemotherapy and enable personalised treatment, the need of biomarkers is of great significance. In this study, we evaluated the gene expression profiles of the colon cancer cell lines treated with SN-38, the active metabolite of topoisomerase-1 inhibitor......Colorectal cancer is the third most common form of cancer in the industrial countries. Due to advances regarding the treatments, primarily development of improved surgical methods and the ability to make the earlier diagnosis, the mortality has remained constant during the past decades even though...

  1. Variations of flaring kernel sizes in various parts of the H-alpha line profile

    CERN Document Server

    Radziszewski, K

    2012-01-01

    We analyze the temporal variations of the sizes and emission intensities of thirtyone flaring kernels in various parts of the H{\\alpha} line profile. We have found that the areas of all kernels decrease systematically when observed in consecutive wavelengths toward the wings of the H{\\alpha} line, but their areas and emission intensity vary in time. Our results are in agreement with the commonly accepted model of the glass-shaped lower parts of the magnetic flaring loops channelling high energy variable particle beams toward the chromospheric plasma. High time resolution spectral-imaging data used in our work were collected using the Large Coronagraph and Horizontal Telescope equipped with the Multi-channel Subtractive Double Pass Spectrograph and the Solar Eclipse Coronal Imaging System (MSDP-SECIS) at the Bia{\\l}k\\'ow Observatory of the University of Wroc{\\l}aw, Poland.

  2. Sizes of flaring kernels in various parts of the Hα line profile

    Directory of Open Access Journals (Sweden)

    K. Radziszewski

    2008-10-01

    Full Text Available In this paper we present new results of spectra-photometrical investigations of the flaring kernels' sizes and their intensities measured simultaneously in various parts of the Hα line profile. Our investigations were based on the very high temporal resolution spectral-imaging observations of the solar flares collected with Large Coronagraph (LC, Multi-channel Subtractive Double Pass Spectrograph and Solar Eclipse Coronal Imaging System (MSDP-SECIS at Białkow Observatory (University of Wrocław, Poland.

    We have found that the areas of the investigated individual flaring kernels vary in time and in wavelengths, as well as the intensities and areas of the Hα flaring kernels decreased systematically when observed in consecutive wavelengths toward the wings of the Hα line. Our result could be explained as an effect of the cone-shaped lower parts of the magnetic loops channeling high energy particle beams exciting chromospheric plasma.

  3. On the emitting region of X-ray fluorescent lines around Compton-thick AGN

    CERN Document Server

    Liu, Jiren

    2016-01-01

    X-ray fluorescent lines are unique features of the reflection spectrum of the torus when irradiated by the central AGN. Their intrinsic line width can be used to probe the line-emitting region. Previous studies have focused on the Fe Ka line at 6.4 keV, which is the most prominent fluorescent line. These studies, however, are limited by the spectral resolution of currently available instruments, the best of which is $\\sim1860$ km s$^{-1}$ afforded by the Chandra High-Energy Grating (HEG). The HEG spectral resolution is improved by a factor of 4 at 1.74 keV, where the Si Ka line is located. We measured the FWHM of the Si Ka line for Circinus, Mrk 3, and NGC 1068, which are $570\\pm240$, $730\\pm320$, and $320\\pm280$ km s$^{-1}$, respectively. They are $3-5$ times smaller than those measured with the Fe Ka line previously. It shows that the intrinsic widths of the Fe Ka line are most likely to be over-estimated. The measured widths of the Si Ka line put the line-emitting region outside the dust sublimation radius...

  4. Revealing deuterium Balmer lines in HII regions with VLT-UVES

    CERN Document Server

    Hébrard, G; Walsh, J R; Vidal-Madjar, A; Ferlet, R

    2000-01-01

    The search for deuterium Balmer lines with VLT-UVES is reported in HII regions of the Galaxy and the Magellanic Clouds. The DI lines appear as faint, narrow emission features in the blue wings of the HI Balmer lines and can be distinguished from high-velocity HI emission. The previous identification to deuterium is re-inforced beyond doubt. The detection of D-alpha and D-beta in Orion (Hebrard et al. 2000) is confirmed and deuterium lines are now detected up to at least D-eta. The UVES observations provide the first detection of Balmer DI lines in four new HII regions (M 8, M 16, M 20, and DEM S 103 in SMC), demonstrating that these lines are of common occurence.

  5. Genetic parameters and crossbreeding effects of fat deposition and fatty acid profiles in Iberian pig lines.

    Science.gov (United States)

    Ibáñez-Escriche, N; Magallón, E; Gonzalez, E; Tejeda, J F; Noguera, J L

    2016-01-01

    The aim of this study was to estimate the genetic and environmental parameters and crossbreeding effects on fatty acid and fat traits in the Iberian pig. Our final goal is to explore target selection traits and define crossbreeding strategies. The phenotypes were obtained under intensive management from 470 animals in a diallelic experiment involving Retinto, Torbiscal, and Entrepelado lines. The data set was composed of backfat thickness at the fourth rib (BFT), intramuscular fat (IMF) in the longissimus thoracis (LT), and the fatty acid profile for IMF and subcutaneous fat (SCF) traits. Data were analyzed through a Bayesian bivariate animal model by using a reparameterization of Dickerson's model. The results obtained showed an important genetic determinism for all traits analyzed with heritability ranging from 0.09 to 0.67. The common environment litter effect also had an important effect on IMF (0.34) and its fatty acid composition (0.06-0.53) at slaughter. The additive genetic correlation between BFT and IMF (additive genetic correlation [] = 0.31) suggested that it would be possible to improve lean growth independent of the IMF with an appropriate selection index. Furthermore, the high additive genetic correlation ( = 0.68) found between MUFA tissues would seem to indicate that either the LT or SCF could be used as the reference tissue for MUFA selection. The relevance of the crossbreeding parameters varied according to the traits analyzed. Backfat thickness at the fourth rib and the fatty acid profile of the IMF showed relevant differences between crosses, mostly due to line additive genetic effects associated with the Retinto line. On the contrary, those for IMF crosses were probably mainly attributable to heterosis effects. Particularly, heterosis effects were relevant for the Retinto and Entrepelado crosses (approximately 16% of the trait), which could be valuable for a crossbreeding system involving these lines.

  6. K$\\alpha$ iron line profile from accretion disks around regular and singular exotic compact objects

    CERN Document Server

    Bambi, Cosimo

    2013-01-01

    The nature of the super-massive black hole candidates in galactic nuclei can be tested by analyzing the profile of the K$\\alpha$ iron line observed in their X-ray spectrum. In this paper, we consider the possibility that the spacetime in the immediate vicinity of these objects may be described by some non vacuum exact solutions of Einstein's equations resulting as the end-state of gravitational collapse. The vacuum far away portion of the spacetime is described by the Schwarzschild metric, while the interior part may be either regular or have a naked singularity at the center. The iron line generated around this class of objects has specific features, which can be used to distinguish such objects from Kerr black holes. In particular, their iron line cannot have the characteristic low-energy tail of the line generated from accretion disks around fast-rotating Kerr black holes. We can thus conclude that the super-massive black hole candidates whose spin parameter has been estimated to be close to 1 assuming the...

  7. Derivation and transcriptional profiling analysis of pluripotent stem cell lines from rat blastocysts

    Institute of Scientific and Technical Information of China (English)

    Chunliang Li; Ying Yang; Junjie Gu; Yu Ma; Ying Jin

    2009-01-01

    Embryonic stem (ES) cells are derived from blastocyst-stage embryos. Their unique properties of self-renewal and pluripotency make them an attractive tool for basic research and a potential cell resource for therapy. ES cells of mouse and human have been successfully generated and applied in a wide range of research. However, no genuine ES cell lines have been obtained from rat to date. In this study, we identified pluripotent cells in early rat embryos using specific antibodies against markers of pluripotent stem cells. Subsequently, by modifying the culture medium for rat blastocysts, we derived pluripotent rat ES-llke cell lines, which expressed pluripotency markers and formed embryoid bodies (EBs) in vitro. Importantly, these rat ES-like cells were able to produce teratomas. Both EBs and teratomas contained tissues from all three embryonic germ layers, in addition, from the rat ES-like cells, we derived a rat primitive endoderm (PrE) cell line. Furthermore, we conducted transcriptional profiling of the rat ES-like cells and identified the unique molecular signature of the rat pluripotent stem cells. Our analysis demonstrates that multiple signaling pathways, including the BMP, Activin and roTOR pathways, may be involved in keeping the rat ES-like cells in an undifferentiated state. The cell lines and information obtained in this study will accelerate our understanding of the molecular regulation underlying pluripotency and guide us in the appropriate manipulation of ES cells from a particular species.

  8. THE GENE EXPRESSION PROFILE OF HIGHLY METASTATIC HUMAN OVARIAN CANCER CELL LINE BY GENE CHIP

    Institute of Scientific and Technical Information of China (English)

    吕桂泉; 许沈华; 牟瀚舟; 朱赤红; 羊正炎; 高永良; 楼洪坤; 刘祥麟; 杨文; 程勇

    2001-01-01

    To study the gene expression of high metastatic human ovarian carcinoma cell line (HO-8910PM) and to screen for novel metastasis- associated genes by cDNA microarray. Methods: The cDNA was retro-transcribed from equal quantity mRNA derived from tissues of highly metastatic ovarian carcinoma cell line and normal ovarian, and was labeled with Cy5 and Cy3 fluorescence as probes. The mixed probes were hybridized with BioDoor 4096 double dot human whole gene chip. The chip was scanned by scanArray 3000 laser scanner. The acquired image was analyzed by ImaGene 3.0 software. Results: By applying the cDNA microarray we found: A total of 323 genes whose expression level were 3 times higher or lower in HO-8910PM cell than normal ovarian epithelium cell were screened out, with 71 higher and 252 lower respectively. Among these 10 were new genes. 67 genes showed expression difference bigger than 6 times between HO-8910PM cell and normal ovarian epithelium cell, among these genes 12 were higher, 55 lower, and two new genes were found. Conclusion: cDNA microarray technique is effective in screening the differentially expressed genes between human ovarian cancer cell line (HO-8910PM) and normal ovarian epithelium cell. Using the cDNA microarray to analyze of human ovarian cancer cell line gene expression profile difference will help the gene diagnosis, treatment and protection.

  9. Cloudy 94 and applications to quasar emission line regions

    Directory of Open Access Journals (Sweden)

    Gary J. Ferland

    2000-01-01

    Full Text Available Se describen los desarrollos recientes del c odigo Cloudy, en su versi on 94, realizados a partir de la versi on anterior C90 (Ferland et al. 1998, as como su aplicaci on a regiones de l neas de emisi on en cuasares. Este c odigo, desarrollado de la forma en que un observador contruir a un espectr ometro, es una herramienta poderosa para obtener la composici on qu mica del gas y la luminosidad de cualquier fuente de l neas de emisi on. El avance reciente m as importante es el modelo \\Lo- cally Optimally-emitting Cloud" (LOC para la regi on de l neas de emisi on en AGN (Baldwin et al. 1995. Se muestra que varios efectos de selecci on, junto con la am- plia gama de condiciones del gas, impiden obtener informaci on sobre los detalles de los emisores. Esto es un avance importante que permite concentrarnos en la infor- maci on relevante, como son la luminosidad y composici on qu mica de los cuasares.

  10. Reverberation Mapping of the Broad Line Region: application to a hydrodynamical line-driven disk wind solution

    CERN Document Server

    Waters, Tim; Proga, Daniel; Eracleous, Michael; Barth, Aaron J; Greene, Jenny

    2016-01-01

    The latest analysis efforts in reverberation mapping are beginning to allow reconstruction of echo images (or velocity-delay maps) that encode information about the structure and kinematics of the broad line region (BLR) in active galactic nuclei (AGNs). Such maps can constrain sophisticated physical models for the BLR. The physical picture of the BLR is often theorized to be a photoionized wind launched from the AGN accretion disk. Previously we showed that the line-driven disk wind solution found in an earlier simulation by Proga and Kallman is virialized over a large distance from the disk. This finding implies that, according to this model, black hole masses can be reliably estimated through reverberation mapping techniques. However, predictions of echo images expected from line-driven disk winds are not available. Here, after presenting the necessary radiative transfer methodology, we carry out the first calculations of such predictions. We find that the echo images are quite similar to other virialized ...

  11. Data-driven dissection of emission-line regions in Seyfert galaxies

    CERN Document Server

    Villarroel, Beatriz

    2016-01-01

    Indirectly resolving the line-emitting gas regions in distant Active Galactic Nuclei (AGN) requires both high-resolution photometry and spectroscopy (i.e. through reverberation mapping). Emission in AGN originates on widely different scales; the broad-line region (BLR) has a typical radius less than a few parsec, the narrow-line region (NLR) extends out to hundreds of parsecs. But emission also appears on large scales from heated nebulae in the host galaxies (tenths of kpc). We propose a novel, data-driven method based on correlations between emission-line fluxes to identify which of the emission lines are produced in the same kind of emission-line regions. We test the method on Seyfert galaxies from the Sloan Digital Sky Survey (SDSS) Data Release 7 (DR7) and Galaxy Zoo project. We demonstrate the usefulness of the method on Seyfert-1s and Seyfert-2 objects, showing similar narrow-line regions (NLRs). Preliminary results from comparing Seyfert-2s in spiral and elliptical galaxy hosts suggest that the presenc...

  12. Technical design and system implementation of region-line primitive association framework

    Science.gov (United States)

    Wang, Min; Xing, Jinjin; Wang, Jie; Lv, Guonian

    2017-08-01

    Apart from regions, image edge lines are an important information source, and they deserve more attention in object-based image analysis (OBIA) than they currently receive. In the region-line primitive association framework (RLPAF), we promote straight-edge lines as line primitives to achieve powerful OBIAs. Along with regions, straight lines become basic units for subsequent extraction and analysis of OBIA features. This study develops a new software system called remote-sensing knowledge finder (RSFinder) to implement RLPAF for engineering application purposes. This paper introduces the extended technical framework, a comprehensively designed feature set, key technology, and software implementation. To our knowledge, RSFinder is the world's first OBIA system based on two types of primitives, namely, regions and lines. It is fundamentally different from other well-known region-only-based OBIA systems, such as eCogntion and ENVI feature extraction module. This paper has important reference values for the development of similarly structured OBIA systems and line-involved extraction algorithms of remote sensing information.

  13. Gravitational Microlensing of a Reverberating Quasar Broad Line Region - I. Method and Qualitative Results

    CERN Document Server

    Garsden, H; Lewis, G F

    2011-01-01

    The kinematics and morphology of the broad emission line region (BELR) of quasars are the subject of significant debate. The two leading methods for constraining BELR properties are microlensing and reverberation mapping. Here we combine these two methods with a study of the microlensing behaviour of the BELR in Q2237+0305, as a change in continuum emission (a "flare") passes through it. Beginning with some generic models of the BELR - sphere, bicones, disk - we slice in velocity and time to produce brightness profiles of the BELR over the duration of the flare. These are numerically microlensed to determine whether microlensing of reverberation mapping provides new information about the properties of BELRs. We describe our method and show images of the models as they are flaring, and the unlensed and lensed spectra that are produced. Qualitative results and a discussion of the spectra are given in this paper, highlighting some effects that could be observed. Our conclusion is that the influence of microlensi...

  14. Demonstration of Current Profile Shaping using Double Dog-Leg Emittance Exchange Beam Line at Argonne Wakefield Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Ha, Gwanghui [Argonne, HEP; Cho, Moo-Hyun [POSTECH; Conde, Manoel [Argonne, HEP; Doran, Darrell [Argonne, HEP; Gai, Wei [Argonne, HEP; Jing, Chunguang [Euclid Techlabs, Solon; Kim, Kwang-Je [Argonne, HEP; Liu, Wanming [Argonne, HEP; Namkung, Won [POSTECH; Piot, Philippe [Northern Illinois U.; Power, John [Argonne, HEP; Sun, Yin-E [Argonne, HEP; Whiteford, Charles [Argonne, HEP; Wisniewski, Eric [Argonne, HEP; Zholents, Alexander [Argonne, HEP

    2016-06-01

    Emittance exchange (EEX) based longitudinal current profile shaping is the one of the promising current profile shaping technique. This method can generate high quality arbitrary current profiles under the ideal conditions. The double dog-leg EEX beam line was recently installed at the Argonne Wakefield Accelerator (AWA) to explore the shaping capability and confirm the quality of this method. To demonstrate the arbitrary current profile generation, several different transverse masks are applied to generate different final current profiles. The phase space slopes and the charge of incoming beam are varied to observe and suppress the aberrations on the ideal profile. We present current profile shaping results, aberrations on the shaped profile, and its suppression.

  15. The galactic unclassified B[e] star HD 50138 III. The short-term line profile variability of its photospheric lines

    CERN Document Server

    Fernandes, Marcelo Borges; Nickeler, Dieter H; De Cat, Peter; Lampens, Patricia; Pereira, Claudio Bastos; Oksala, Mary E

    2012-01-01

    HD 50138 presents the B[e] phenomenon, but its nature is not clear yet. This star is known to present spectral variations, which have been associated with outbursts and shell phases. We analyze the line profile variability of HD 50138 and its possible origin, which provide possible hints to its evolutionary stage, so far said to be close to the end of (or slightly beyond) the main sequence. New high-resolution spectra of HD 50138 obtained with the HERMES spectrograph over several nights (five of them consecutively) were analyzed, allowing us to confirm short-term line profile variability. Our new data show short-term variations in the photospheric lines. On the other hand, purely circumstellar lines (such as [O I] lines) do not show such rapid variability. The rotational velocity of HD 50138, V_rot = 90.3 +- 4.3 km/s, and the rotation period, P = 3.64 +- 1.16 d, were derived from the He II 4026A photospheric line. Based on the moment method, we confirm that the origin of this short-term line profile variabili...

  16. Numerical Evaluation of Parameter Correlation in the Hartmann-Tran Line Profile

    Science.gov (United States)

    Adkins, Erin M.; Reed, Zachary; Hodges, Joseph T.

    2017-06-01

    The partially correlated quadratic, speed-dependent hard-collision profile (pCqSDHCP), for simplicity referred to as the Hartmann-Tran profile (HTP), has been recommended as a generalized lineshape for high resolution spectroscopy. The HTP parameterizes complex collisional effects such as Dicke narrowing, speed dependent narrowing, and correlations between velocity-changing and dephasing collisions, while also simplifying to simpler profiles that are widely used, such as the Voigt profile. As advanced lineshape profiles are adopted by more researchers, it is important to understand the limitations that data quality has on the ability to retrieve physically meaningful parameters using sophisticated lineshapes that are fit to spectra of finite signal-to-noise ratio. In this work, spectra were simulated using the HITRAN Application Programming Interface (HAPI) across a full range of line parameters. Simulated spectra were evaluated to quantify the precision with which fitted lineshape parameters can be determined at a given signal-to-noise ratio, focusing on the numerical correlation between the retrieved Dicke narrowing frequency and the velocity-changing and dephasing collisions correlation parameter. Tran, H., N. Ngo, and J.-M. Hartmann, Journal of Quantitative Spectroscopy and Radiative Transfer 2013. 129: p. 89-100. Tennyson, et al., Pure Appl. Chem. 2014, 86: p. 1931-1943. Kochanov, R.V., et al., Journal of Quantitative Spectroscopy and Radiative Transfer 2016. 177: p. 15-30. Tran, H., N. Ngo, and J.-M. Hartmann, Journal of Quantitative Spectroscopy and Radiative Transfer 2013. 129: p. 199-203.

  17. Failed Radiatively Accelerated Dusty Outflow Model of the Broad Line Region in Active Galactic Nuclei. I. Analytical Solution

    Science.gov (United States)

    Czerny, B.; Li, Yan-Rong; Hryniewicz, K.; Panda, S.; Wildy, C.; Sniegowska, M.; Wang, J.-M.; Sredzinska, J.; Karas, V.

    2017-09-01

    The physical origin of the broad line region in active galactic nuclei is still unclear despite many years of observational studies. The reason is that the region is unresolved, and the reverberation mapping results imply a complex velocity field. We adopt a theory-motivated approach to identify the principal mechanism responsible for this complex phenomenon. We consider the possibility that the role of dust is essential. We assume that the local radiation pressure acting on the dust in the accretion disk atmosphere launches the outflow of material, but higher above the disk the irradiation from the central parts causes dust evaporation and a subsequent fallback. This failed radiatively accelerated dusty outflow is expected to represent the material forming low ionization lines. In this paper we formulate simple analytical equations to describe the cloud motion, including the evaporation phase. The model is fully described just by the basic parameters of black hole mass, accretion rate, black hole spin, and viewing angle. We study how the spectral line generic profiles correspond to this dynamic. We show that the virial factor calculated from our model strongly depends on the black hole mass in the case of enhanced dust opacity, and thus it then correlates with the line width. This could explain why the virial factor measured in galaxies with pseudobulges differs from that obtained from objects with classical bulges, although the trend predicted by the current version of the model is opposite to the observed trend.

  18. Cell Line Derived 5-FU and Irinotecan Drug-Sensitivity Profiles Evaluated in Adjuvant Colon Cancer Trial Data

    DEFF Research Database (Denmark)

    Buhl, Ida Kappel; Gerster, Sarah; Delorenzi, Mauro

    2016-01-01

    patients who benefitted from the addition of irinotecan to 5-FU, we used gene expression profiles based on cell lines and clinical tumor material. These profiles were applied to expression data obtained from pretreatment formalin fixed paraffin embedded (FFPE) tumor tissue from 636 stage III colon cancer...

  19. Modification of SOL profiles and fluctuations with line-average density and divertor flux expansion in TCV

    DEFF Research Database (Denmark)

    Vianello, N.; Tsui, C.; Theiler, C.

    2017-01-01

    that this modification does not influence neither the detachment density threshold, nor the development of a flat SOL density profile which instead depends strongly on the increase of the core line average density. The modification of the SOL upstream profile, with the appearance of what is generally called a density...

  20. Outflows from AGN: Kinematics of the Narrow-Line and Coronal-Line Regions in Seyfert Galaxies

    CERN Document Server

    Müller-Sánchez, F; Hicks, E K S; Vives-Arias, H; Davies, R I; Malkan, M; Tacconi, L J; Genzel, R

    2011-01-01

    As part of an extensive study of the physical properties of active galactic nuclei (AGN) we report high spatial resolution near-IR integral-field spectroscopy of the narrow-line region (NLR) and coronal-line region (CLR) of seven Seyfert galaxies. These measurements elucidate for the first time the two-dimensional spatial distribution and kinematics of the recombination line Br{\\gamma} and high-ionization lines [Sivi], [Alix] and [Caviii] on scales <300 pc from the AGN. The observations reveal kinematic signatures of rotation and outflow in the NLR and CLR. The spatially resolved kinematics can be modeled as a combination of an outflow bicone and a rotating disk coincident with the molecular gas. High-excitation emission is seen in both components, suggesting it is leaking out of a clumpy torus. While NGC 1068 (Seyfert 2) is viewed nearly edge-on, intermediate-type Seyferts are viewed at intermediate angles, consistent with unified schemes. A correlation between the outflow velocity and the molecular gas m...

  1. The 3D scanner prototype utilize object profile imaging using line laser and octave software

    Science.gov (United States)

    Nurdini, Mugi; Manunggal, Trikarsa Tirtadwipa; Samsi, Agus

    2016-11-01

    Three-dimensional scanner or 3D Scanner is a device to reconstruct the real object into digital form on a computer. 3D Scanner is a technology that is being developed, especially in developed countries, where the current 3D Scanner devices is the advanced version with a very expensive prices. This study is basically a simple prototype of 3D Scanner with a very low investment costs. 3D Scanner prototype device consists of a webcam, a rotating desk system controlled by a stepper motor and Arduino UNO, and a line laser. Objects that limit the research is the object with same radius from its center point (object pivot). Scanning is performed by using object profile imaging by line laser which is then captured by the camera and processed by a computer (image processing) using Octave software. On each image acquisition, the scanned object on a rotating desk rotated by a certain degree, so for one full turn multiple images of a number of existing side are finally obtained. Then, the profile of the entire images is extracted in order to obtain digital object dimension. Digital dimension is calibrated by length standard, called gage block. Overall dimensions are then digitally reconstructed into a three-dimensional object. Validation of the scanned object reconstruction of the original object dimensions expressed as a percentage error. Based on the results of data validation, horizontal dimension error is about 5% to 23% and vertical dimension error is about +/- 3%.

  2. Modelling chromospheric line profiles as diagnostics of velocity fields in {\\omega} Centauri red giant stars

    CERN Document Server

    Vieytes, M; Cacciari, C; Origlia, L; Pancino, E

    2010-01-01

    Context. Mass loss of ~0.1-0.3 M$_{\\odot}$ from Population II red giant stars (RGB) is a requirement of stellar evolution theory in order to account for several observational evidences in globular clusters. Aims. The aim of this study is to detect the presence of outward velocity fields, which are indicative of mass outflow, in six luminous red giant stars of the stellar cluster {\\omega} Cen. Methods. We compare synthetic line profiles computed using relevant model chromospheres to observed profiles of the H{\\alpha} and Ca II K lines. The spectra were taken with UVES (R=45,000) and the stars were selected so that three of them belong to the metal-rich population and three to the metal-poor population, and sample as far down as 1 to 2.5 magnitudes fainter than the respective RGB tips. Results. We do indeed reveal the presence of low-velocity outward motions in four of our six targets, without any apparent correlation with astrophysical parameters. Conclusions. This provides direct evidence that outward velocit...

  3. A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines

    Directory of Open Access Journals (Sweden)

    Rognum Torleiv O

    2004-10-01

    Full Text Available Abstract Background Tumor cell lines are commonly used as experimental tools in cancer research, but their relevance for the in vivo situation is debated. In a series of 11 microsatellite stable (MSS and 9 microsatellite unstable (MSI colon cancer cell lines and primary colon carcinomas (25 MSS and 28 MSI with known ploidy stem line and APC, KRAS, and TP53 mutation status, we analyzed the promoter methylation of the following genes: hMLH1, MGMT, p16INK4a (CDKN2A α-transcript, p14ARF (CDKN2A β-transcript, APC, and E-cadherin (CDH1. We compared the DNA methylation profiles of the cell lines with those of the primary tumors. Finally, we examined if the epigenetic changes were associated with known genetic markers and/or clinicopathological variables. Results The cell lines and primary tumors generally showed similar overall distribution and frequencies of gene methylation. Among the cell lines, 15%, 50%, 75%, 65%, 20% and 15% showed promoter methylation for hMLH1, MGMT, p16INK4a, p14ARF, APC, and E-cadherin, respectively, whereas 21%, 40%, 32%, 38%, 32%, and 40% of the primary tumors were methylated for the same genes. hMLH1 and p14ARF were significantly more often methylated in MSI than in MSS primary tumors, whereas the remaining four genes showed similar methylation frequencies in the two groups. Methylation of p14ARF, which indirectly inactivates TP53, was seen more frequently in tumors with normal TP53 than in mutated samples, but the difference was not statistically significant. Methylation of p14ARF and p16INK4a was often present in the same primary tumors, but association to diploidy, MSI, right-sided location and female gender was only significant for p14ARF. E-cadherin was methylated in 14/34 tumors with altered APC further stimulating WNT signaling. Conclusions The present study shows that colon cancer cell lines are in general relevant in vitro models, comparable with the in vivo situation, as the cell lines display many of the same

  4. Weak-Line Quasars at High Redshift: Extremely High Accretion Rates or Anemic Broad-Line Regions?

    CERN Document Server

    Shemmer, Ohad; Anderson, Scott F; Brandt, W N; Diamond-Stanic, Aleksandar M; Fan, Xiaohui; Lira, Paulina; Netzer, Hagai; Plotkin, Richard M; Richards, Gordon T; Schneider, Donald P; Strauss, Michael A

    2010-01-01

    We present Gemini-North K-band spectra of two representative members of the class of high-redshift quasars with exceptionally weak rest-frame ultraviolet emission lines (WLQs), SDSS J114153.34+021924.3 at z=3.55 and SDSS J123743.08+630144.9 at z=3.49. In both sources we detect an unusually weak broad H_beta line and we place tight upper limits on the strengths of their [O III] lines. Virial, H_beta-based black-hole mass determinations indicate normalized accretion rates of L/L_Edd=0.4 for these sources, which is well within the range observed for typical quasars with similar luminosities and redshifts. We also present high-quality XMM-Newton imaging spectroscopy of SDSS J114153.34+021924.3 and find a hard-X-ray photon index of Gamma=1.91^{+0.24}_{-0.22} which supports the virial L/L_Edd determination in this source. Our results suggest that the weakness of the broad-emission lines in WLQs is not a consequence of an extreme continuum-emission source but instead due to abnormal broad-emission line region proper...

  5. Kinetic Energy Distribution of D(2p) Atoms From Analysis of the D Lyman-a Line Profile

    Science.gov (United States)

    Ciocca, Marco; Ajello, Joseph M.; Liu, Xianming; Maki, Justin

    1997-01-01

    The absolute cross sections of the line center (slow atoms) and wings (fast atoms) and total emission line profile were measured from threshold to 400 eV. Analytical model coeffiecients are given for the energy dependence of the measured slow atom cross section.

  6. On the origins of C IV absorption profile diversity in broad absorption line quasars

    CERN Document Server

    Baskin, Alexei; Hamann, Fred

    2015-01-01

    There is a large diversity in the C IV broad absorption line (BAL) profile among BAL quasars (BALQs). We quantify this diversity by exploring the distribution of the C IV BAL properties, FWHM, maximum depth of absorption and its velocity shift ($v_{\\rm md}$), using the SDSS DR7 quasar catalogue. We find the following: (i) Although the median C IV BAL profile in the quasar rest-frame becomes broader and shallower as the UV continuum slope ($\\alpha_{\\rm UV}$ at 1700-3000 A) gets bluer, the median individual profile in the absorber rest-frame remains identical, and is narrow (FWHM = 3500 km/s) and deep. Only 4 per cent of BALs have FWHM > 10,000 km/s. (ii) As the He II emission equivalent-width (EW) decreases, the distributions of FWHM and $v_{\\rm md}$ extend to larger values, and the median maximum depth increases. These trends are consistent with theoretical models in which softer ionizing continua reduce overionization, and allow radiative acceleration of faster BAL outflows. (iii) As $\\alpha_{\\rm UV}$ become...

  7. Asymmetric profiles and prewetting lines in the filling of planar slits with Ne.

    Science.gov (United States)

    Sartarelli, Salvador A; Szybisz, Leszek

    2013-05-23

    The filling of slits with identical planar walls is investigated in the frame of the density functional theory. For this kind of slit, the confining potential is symmetric with respect to its central plane. Closed and open systems are studied by applying, respectively, the canonical and grand canonical ensembles (CE and GCE). Results obtained for the confinement of fluid Ne by alkaline surfaces are reported. The behavior of these systems is analyzed by varying the strength of the Ne-substrate attraction, the temperature T, and the coverage Γ(l). It is assumed that the one-body density of the fluid, ρ(r), is uniform along the (x, y) planes parallel to the walls, becoming a function of the coordinate z perpendicular to those planes. Two sorts of solutions are found for the density profile: (i) symmetric ones that follow the left-right symmetry of the potential exerted by the walls and (ii) asymmetric ones that break the symmetry of the slit. The pores are wide enough for determining prewetting (PW) lines and wetting and critical PW temperatures, i.e., T(w) and T(cpw), from the analysis of symmetric solutions provided by both the CE and GCE schemes. Asymmetric species are examined in detail for T > T(w). It is shown that for a given Ne-substrate pair at a fixed T both the CE and GCE frames yield only one asymmetric 2-fold degenerate stable profile (formed by a "thin" wetting film at one wall and a "thick" wetting film at the other) coexisting with two symmetric profiles (formed by "thin" or "thick" wetting films at the two walls), while the remaining asymmetric states are at best metastable. This feature occurs along PW lines and disappears at T(cpw).

  8. Polyphenolic Profile and Targeted Bioactivity of Methanolic Extracts from Mediterranean Ethnomedicinal Plants on Human Cancer Cell Lines

    Directory of Open Access Journals (Sweden)

    Antonino Pollio

    2016-03-01

    Full Text Available The methanol extracts of the aerial part of four ethnomedicinal plants of Mediterranean region, two non-seed vascular plants, Equisetum hyemale L. and Phyllitis scolopendrium (L. Newman, and two Spermatophyta, Juniperus communis L. (J. communis and Cotinus coggygria Scop. (C. coggygria, were screened against four human cells lines (A549, MCF7, TK6 and U937. Only the extracts of J. communis and C. coggygria showed marked cytotoxic effects, affecting both cell morphology and growth. A dose-dependent effect of these two extracts was also observed on the cell cycle distribution. Incubation of all the cell lines in a medium containing J. communis extract determined a remarkable accumulation of cells in the G2/M phase, whereas the C. coggygria extract induced a significant increase in the percentage of G1 cells. The novelty of our findings stands on the observation that the two extracts, consistently, elicited coherent effects on the cell cycle in four cell lines, independently from their phenotype, as two of them have epithelial origin and grow adherent and two are lymphoblastoid and grow in suspension. Even the expression profiles of several proteins regulating cell cycle progression and cell death were affected by both extracts. LC-MS investigation of methanol extract of C. coggygria led to the identification of twelve flavonoids (compounds 1–11, 19 and eight polyphenols derivatives (12–18, 20, while in J. communis extract, eight flavonoids (21–28, a α-ionone glycoside (29 and a lignin (30 were found. Although many of these compounds have interesting individual biological activities, their natural blends seem to exert specific effects on the proliferation of cell lines either growing adherent or in suspension, suggesting potential use in fighting cancer.

  9. Recovery of acetylene absorption line profile basing on tunable diode laser spectroscopy with intensity modulation and photoacoustic spectroscopy

    Science.gov (United States)

    Li, Li; Thursby, Graham; Stewart, George; Arsad, Norhana; Uttamchandani, Deepak; Culshaw, Brian; Wang, Yiding

    2010-04-01

    A novel and direct absorption line recovery technique based on tunable diode laser spectroscopy with intensity modulation is presented. Photoacoustic spectroscopy is applied for high sensitivity, zero background and efficient acoustic enhancement at a low modulation frequency. A micro-electromechanical systems (MEMS) mirror driven by an electrothermal actuator is used for generating laser intensity modulation (without wavelength modulation) through the external reflection. The MEMS mirror with 10μm thick structure material layer and 100nm thick gold coating is formed as a circular mirror of 2mm diameter attached to an electrothermal actuator and is fabricated on a chip that is wire-bonded and placed on a PCB holder. Low modulation frequency is adopted (since the resonant frequencies of the photoacoustic gas cell and the electrothermal actuator are different) and intrinsic high signal amplitude characteristics in low frequency region achieved from measured frequency responses for the MEMS mirror and the gas cell. Based on the property of photoacoustic spectroscopy and Beer's law that detectable sensitivity is a function of input laser intensity in the case of constant gas concentration and laser path length, a Keopsys erbium doped fibre amplifier (EDFA) with opto-communication C band and high output power up to 1W is chosen to increase the laser power. High modulation depth is achieved through adjusting the MEMS mirror's reflection position and driving voltage. In order to scan through the target gas absorption line, the temperature swept method is adopted for the tunable distributed feed-back (DFB) diode laser working at 1535nm that accesses the near-infrared vibration-rotation spectrum of acetylene. The profile of acetylene P17 absorption line at 1535.39nm is recovered ideally for ~100 parts-per-million (ppm) acetylene balanced by nitrogen. The experimental signal to noise ratio (SNR) of absorption line recovery for 500mW laser power was ~80 and hence the

  10. Polyphenolic Profile and Targeted Bioactivity of Methanolic Extracts from Mediterranean Ethnomedicinal Plants on Human Cancer Cell Lines.

    Science.gov (United States)

    Pollio, Antonino; Zarrelli, Armando; Romanucci, Valeria; Di Mauro, Alfredo; Barra, Federica; Pinto, Gabriele; Crescenzi, Elvira; Roscetto, Emanuela; Palumbo, Giuseppe

    2016-03-23

    The methanol extracts of the aerial part of four ethnomedicinal plants of Mediterranean region, two non-seed vascular plants, Equisetum hyemale L. and Phyllitis scolopendrium (L.) Newman, and two Spermatophyta, Juniperus communis L. (J. communis) and Cotinus coggygria Scop. (C. coggygria), were screened against four human cells lines (A549, MCF7, TK6 and U937). Only the extracts of J. communis and C. coggygria showed marked cytotoxic effects, affecting both cell morphology and growth. A dose-dependent effect of these two extracts was also observed on the cell cycle distribution. Incubation of all the cell lines in a medium containing J. communis extract determined a remarkable accumulation of cells in the G2/M phase, whereas the C. coggygria extract induced a significant increase in the percentage of G1 cells. The novelty of our findings stands on the observation that the two extracts, consistently, elicited coherent effects on the cell cycle in four cell lines, independently from their phenotype, as two of them have epithelial origin and grow adherent and two are lymphoblastoid and grow in suspension. Even the expression profiles of several proteins regulating cell cycle progression and cell death were affected by both extracts. LC-MS investigation of methanol extract of C. coggygria led to the identification of twelve flavonoids (compounds 1-11, 19) and eight polyphenols derivatives (12-18, 20), while in J. communis extract, eight flavonoids (21-28), a α-ionone glycoside (29) and a lignin (30) were found. Although many of these compounds have interesting individual biological activities, their natural blends seem to exert specific effects on the proliferation of cell lines either growing adherent or in suspension, suggesting potential use in fighting cancer.

  11. INTRAPRENEURIAL PROFILE AND ACTIONS OF ACCOUNTING COURSE ADMINISTRATORS IN THE WESTERN REGION OF PARANA

    National Research Council Canada - National Science Library

    Maria José Carvalho de Souza Domingues; Daniela Torres da Rocha; Márcia Andréia Schneider; Silvana Anita Walter; Gérson Tontini

    2012-01-01

    This article aims to identify and analyze the intrapreneurial actions, profile, and characteristics of the administrators for undergraduate courses of Accounting Sciences in the western region of Paraná...

  12. Autoantibody profiling of patients with primary biliary cirrhosis using a multiplexed line-blot assay.

    Science.gov (United States)

    Villalta, Danilo; Sorrentino, Maria Concetta; Girolami, Elia; Tampoia, Marilina; Alessio, Maria Grazia; Brusca, Ignazio; Daves, Massimo; Porcelli, Brunetta; Barberio, Giuseppina; Bizzaro, Nicola

    2015-01-01

    To evaluate the autoantibody profile in patients with primary biliary cirrhosis (PBC) using a new multiplexed line-blot assay specifically designed for the diagnosis of autoimmune liver diseases. Sera of 58 consecutive PBC patients and 191 disease controls (144 with autoimmune liver diseases other than PBC, and 67 with non-autoimmune chronic liver diseases) were tested by both the multiplexed line-blot Autoimmune Liver Disease Profile 2 (ALD2) and by IIF on HEp-2 cells and on rat kidney/liver/stomach tissues. ALD2 contains the following PBC-associated antigens: AMA-M2, natively purified from bovine heart; M2-E3, a recombinant fusion protein including the E2 subunits of PDC, BCOADC and OGDC; sp100, PML and gp210 recombinant proteins. With the ALD2 assay, a positive reaction to AMA-M2, M2-E3, sp100, PML and gp210 in PBC patients was observed in 77.6%, 84.5%, 34.5%, 15.1% and 18.9%, respectively, of the PBC sera. The overall sensitivity and specificity for PBC were 98.3% and 93.7%. Using IIF, positivity rates to AMA, and to antinuclear autoantibodies with membranous/rim-like and multiple nuclear dot patterns were 86.2%, 8.6% and 22.4%, respectively. The overall sensitivity and specificity for PBC of the IIF method were 86.2% and 97.9%, respectively. The ALD2 line-blot showed a good diagnostic accuracy for PBC and a higher sensitivity than the IIF method to detect sp100 and gp210 autoantibodies. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. Mars Ozone Absorption Line Shapes from Infrared Heterodyne Spectra Applied to GCM-Predicted Ozone Profiles and to MEX/SPICAM Column Retrievals

    Science.gov (United States)

    Fast, Kelly E.; Kostiuk, T.; Annen, J.; Hewagama, T.; Delgado, J.; Livengood, T. A.; Lefevre, F.

    2008-01-01

    We present the application of infrared heterodyne line shapes of ozone on Mars to those produced by radiative transfer modeling of ozone profiles predicted by general circulation models (GCM), and to contemporaneous column abundances measured by Mars Express SPICAM. Ozone is an important tracer of photochemistry Mars' atmosphere, serving as an observable with which to test predictions of photochemistry-coupled GCMs. Infrared heterodyne spectroscopy at 9.5 microns with spectral resolving power >1,000,000 is the only technique that can directly measure fully-resolved line shapes of Martian ozone features from the surface of the Earth. Measurements were made with Goddard Space Flight Center's Heterodyne instrument for Planetary Wind And Composition (HIPWAC) at the NASA Infrared Telescope Facility (IRTF) on Mauna Kea, Hawaii on February 21-24 2008 UT at Ls=35deg on or near the MEX orbital path. The HIPWAC observations were used to test GCM predictions. For example, a GCM-generated ozone profile for 60degN 112degW was scaled so that a radiative transfer calculation of its absorption line shape matched an observed HIPWAC absorption feature at the same areographic position, local time, and season. The RMS deviation of the model from the data was slightly smaller for the GCM-generated profile than for a line shape produced by a constant-with-height profile, even though the total column abundances were the same, showing potential for testing and constraining GCM ozone-profiles. The resulting ozone column abundance from matching the model to the HIPWAC line shape was 60% higher than that observed by SPICAM at the same areographic position one day earlier and 2.5 hours earlier in local time. This could be due to day-to-day, diurnal, or north polar region variability, or to measurement sensitivity to the ozone column and its distribution, and these possibilities will be explored. This work was supported by NASA's Planetary Astronomy Program.

  14. Mars Ozone Absorption Line Shapes from Infrared Heterodyne Spectra Applied to GCM-Predicted Ozone Profiles and to MEX/SPICAM Column Retrievals

    Science.gov (United States)

    Fast, Kelly E.; Kostiuk, T.; Annen, J.; Hewagama, T.; Delgado, J.; Livengood, T. A.; Lefevre, F.

    2008-01-01

    We present the application of infrared heterodyne line shapes of ozone on Mars to those produced by radiative transfer modeling of ozone profiles predicted by general circulation models (GCM), and to contemporaneous column abundances measured by Mars Express SPICAM. Ozone is an important tracer of photochemistry Mars' atmosphere, serving as an observable with which to test predictions of photochemistry-coupled GCMs. Infrared heterodyne spectroscopy at 9.5 microns with spectral resolving power >1,000,000 is the only technique that can directly measure fully-resolved line shapes of Martian ozone features from the surface of the Earth. Measurements were made with Goddard Space Flight Center's Heterodyne instrument for Planetary Wind And Composition (HIPWAC) at the NASA Infrared Telescope Facility (IRTF) on Mauna Kea, Hawaii on February 21-24 2008 UT at Ls=35deg on or near the MEX orbital path. The HIPWAC observations were used to test GCM predictions. For example, a GCM-generated ozone profile for 60degN 112degW was scaled so that a radiative transfer calculation of its absorption line shape matched an observed HIPWAC absorption feature at the same areographic position, local time, and season. The RMS deviation of the model from the data was slightly smaller for the GCM-generated profile than for a line shape produced by a constant-with-height profile, even though the total column abundances were the same, showing potential for testing and constraining GCM ozone-profiles. The resulting ozone column abundance from matching the model to the HIPWAC line shape was 60% higher than that observed by SPICAM at the same areographic position one day earlier and 2.5 hours earlier in local time. This could be due to day-to-day, diurnal, or north polar region variability, or to measurement sensitivity to the ozone column and its distribution, and these possibilities will be explored. This work was supported by NASA's Planetary Astronomy Program.

  15. Analysis on Energy Conversion of Screw Centrifugal Pump in Impeller Domain Based on Profile Lines

    Directory of Open Access Journals (Sweden)

    Hui Quan

    2013-01-01

    Full Text Available In order to study the power capability of impeller and energy conversion mechanism of screw centrifugal pump, the methods of theoretical analysis and numerical simulation by computational fluid dynamics theory (CFD were adopted, specifically discussing the conditions of internal flow such as velocity, pressure, and concentration. When the medium is sand-water two-phase flow and dividing the rim of the lines and wheel lines of screw centrifugal pump to segments to analyze energy conversion capabilities which along the impeller profile lines with the dynamic head and hydrostatic head changer, the results show that the energy of fluid of the screw centrifugal pump is provided by helical segment, and the helical segment of the front of the impeller has played the role of multilevel increasing energy; the sand-water two phases move at different speeds because the different force field and the impeller propeller and centrifugal effect. As liquid phase is the primary phase, the energy conversion is mainly up to the change of liquid energy, the solid phase flows under the wrapped action of liquid, and solid energy is carried out through liquid indirectly.

  16. Distorted cyclotron line profile in Cep X-4 as observed by NuSTAR

    CERN Document Server

    Fuerst, F; Miyasaka, H; Bhalerao, V; Bachetti, M; Boggs, S E; Christensen, F E; Craig, W W; Grinberg, V; Hailey, C J; Harrison, F A; Kennea, J A; Rahoui, F; Stern, D; Tendulkar, S P; Tomsick, J A; Walton, D J; Wilms, J; Zhang, W W

    2015-01-01

    We present spectral analysis of NuSTAR and Swift observations of Cep X-4 during its outburst in 2014. We observed the source once during the peak of the outburst and once during the decay, finding good agreement in the spectral shape between the observations. We describe the continuum using a powerlaw with a Fermi-Dirac cutoff at high energies. Cep X-4 has a very strong cyclotron resonant scattering feature (CRSF) around 30 keV. A simple absorption-like line with a Gaussian optical depth or a pseudo-Lorentzian profile both fail to describe the shape of the CRSF accurately, leaving significant deviations at the red side of the line. We characterize this asymmetry with a second absorption feature around 19 keV. The line energy of the CRSF, which is not influenced by the addition of this feature, shows a small but significant positive luminosity dependence. With luminosities between (1-6)e36 erg/s, Cep X-4 is below the theoretical limit where such a correlation is expected. This behavior is similar to Vela X-1 a...

  17. DISTORTED CYCLOTRON LINE PROFILE IN CEP X-4 AS OBSERVED BY NuSTAR

    Energy Technology Data Exchange (ETDEWEB)

    Fürst, F.; Miyasaka, H.; Harrison, F. A.; Tendulkar, S. P.; Walton, D. J. [Cahill Center for Astronomy and Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Pottschmidt, K. [CRESST, Department of Physics, and Center for Space Science and Technology, UMBC, Baltimore, MD 21250 (United States); Bhalerao, V. [Inter-University Center for Astronomy and Astrophysics, Ganeshkhind, Pune 411007 (India); Bachetti, M. [Osservatorio Astronomico di Cagliari, I-09047 Selargius (Italy); Boggs, S. E.; Craig, W. W.; Tomsick, J. A. [Space Sciences Laboratory, University of California, Berkeley, CA 94720 (United States); Christensen, F. E. [DTU Space, National Space Institute, Technical University of Denmark, DK-2800 Lyngby (Denmark); Grinberg, V. [Massachusetts Institute of Technology, Kavli Institute for Astrophysics, Cambridge, MA 02139 (United States); Hailey, C. J. [Columbia Astrophysics Laboratory, Columbia University, New York, NY 10027 (United States); Kennea, J. A. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Rahoui, F. [European Southern Observatory, D-85748 Garching bei München (Germany); Stern, D. [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109 (United States); Wilms, J. [Dr. Karl-Remeis-Sternwarte and ECAP, University of Erlangen-Nuremberg, D-96049 Bamberg (Germany); Zhang, W. W. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States)

    2015-06-20

    We present spectral analysis of Nuclear Spectroscopic Telescope Array and Swift observations of Cep X-4 during its outburst in 2014. We observed the source once during the peak of the outburst and once during the decay, finding good agreement in the spectral shape between the observations. We describe the continuum using a power law with a Fermi–Dirac cutoff at high energies. Cep X-4 has a very strong cyclotron resonant scattering feature (CRSF) around 30 keV. A simple absorption-like line with a Gaussian optical depth or a pseudo-Lorentzian profile both fail to describe the shape of the CRSF accurately, leaving significant deviations at the red side of the line. We characterize this asymmetry with a second absorption feature around 19 keV. The line energy of the CRSF, which is not influenced by the addition of this feature, shows a small but significant positive luminosity dependence. With luminosities between (1–6) × 10{sup 36} erg s{sup −1}, Cep X-4 is below the theoretical limit where such a correlation is expected. This behavior is similar to Vela X-1 and we discuss parallels between the two systems.

  18. Inhomogeneous speed effects on H2 vibrational line profiles in ternary mixtures

    Science.gov (United States)

    Joubert, P.; Bruet, X.; Bonamy, J.; Robert, D.; Chaussard, F.; Saint-Loup, R.; Berger, H.

    2000-12-01

    A study of speed inhomogeneous broadening of the hydrogen vibrational line profiles in the collisional regime for ternary mixtures is reported. The Q(1) line of H2 in H2-Ar-N2, H2-He-Ar, and H2-He-N2 mixtures is investigated by high resolution stimulated Raman spectroscopy for various concentrations and temperatures. A model, successfully used for binary mixtures, is extended to ternary mixtures. An excellent agreement is obtained between theory and experiment for H2-Ar-N2, by using the collisional parameters previously obtained from binary mixtures study. For H2-He-Ar and H2-He-N2, H2-He collisions play a "hardening" effect in the H2 soft speed memory mechanism for H2-Ar or H2-N2. The present experimental results allow us, via the frame of our model, to determine the "hardness" parameter values for H2-He (inaccessible from binary mixtures data) and to get an accurate description of the spectral line shape. This study should be useful for hydrogen coherent anti-Stokes Raman spectroscopy thermometry in H2/air flames at high pressure through its possible extension to the H2-N2-H2O system.

  19. VLBA Survey of OH Masers in Star-Forming Regions II: Satellite Lines

    CERN Document Server

    Ruiz-Velasco, A E; Migenes, V; Wiggins, B K

    2016-01-01

    Using the Very Long Baseline Array (VLBA) we performed a high resolution OH maser survey in Galactic star-forming regions (SFRs). We observed all the ground state spectral lines: the main lines at 1665 and 1667 MHz and the satellite lines at 1612 and 1720 MHz. Due to the exceptionality of finding satellite lines in SFRs, we will focus our discussion on those lines. In our sample of 41 OH maser sources, five (12%) showed the 1612 MHz line and ten (24%) showed the 1720 MHz line, with only one source showing both lines. We find that 1720 MHz emission is correlated with the presence of HII regions, suggesting that this emission could be used to diagnose or trace high-mass star formation. We include an analysis of the possible mechanisms that could be causing this correlation as well as assessing the possible relationships between lines in our sample. In particular, the presence of magnetic fields seems to play an important role, as we found Zeeman splitting in four of our sources (W75 N, W3(OH), W51 and NGC 7538)...

  20. Observations and Simulations of the Na i D1 Line Profiles in an M-class Solar Flare

    Science.gov (United States)

    Kuridze, D.; Mathioudakis, M.; Christian, D. J.; Kowalski, A. F.; Jess, D. B.; Grant, S. D. T.; Kawate, T.; Simões, P. J. A.; Allred, J. C.; Keenan, F. P.

    2016-12-01

    We study the temporal evolution of the Na i D1 line profiles in the M3.9 flare SOL2014-06-11T21:03 UT, using observations at high spectral resolution obtained with the Interferometric Bidimensional Spectrometer instrument on the Dunn Solar Telescope combined with radiative hydrodynamic simulations. Our results show a significant increase in the intensities of the line core and wings during the flare. The analysis of the line profiles from the flare ribbons reveals that the Na i D1 line has a central reversal with excess emission in the blue wing (blue asymmetry). We combine RADYN and RH simulations to synthesize Na i D1 line profiles of the flaring atmosphere and find good agreement with the observations. Heating with a beam of electrons modifies the radiation field in the flaring atmosphere and excites electrons from the ground state 3s 2S to the first excited state 3p 2P, which in turn modifies the relative population of the two states. The change in temperature and the population density of the energy states make the sodium line profile revert from absorption into emission. Furthermore, the rapid changes in temperature break the pressure balance between the different layers of the lower atmosphere, generating upflow/downflow patterns. Analysis of the simulated spectra reveals that the asymmetries of the Na i D1 flare profile are produced by the velocity gradients in the lower solar atmosphere.

  1. Elemental Abundances in the Broad Emission Line Region of Quasars at Redshifts larger than 4

    DEFF Research Database (Denmark)

    Dietrich, M.; Appenzeller, I.; Hamann, F.

    2003-01-01

    We present observations of 11 high redshift quasars ($3.9 \\la z \\la 5.0$) observed with low spectral resolution in the restframe ultraviolet using FORS 1 at the VLT UT 1. The emission-line fluxes of strong permitted and intercombination ultraviolet emission lines are measured to estimate the chem......We present observations of 11 high redshift quasars ($3.9 \\la z \\la 5.0$) observed with low spectral resolution in the restframe ultraviolet using FORS 1 at the VLT UT 1. The emission-line fluxes of strong permitted and intercombination ultraviolet emission lines are measured to estimate...... the chemical composition of the line emitting gas. Comparisons to photoionization calculations indicate gas metallicities in the broad emission line region in the range of solar to several times solar. The average of the mean metallicity of each high-z quasar in this sample is $Z/Z_\\odot = 4.3 \\pm 0...

  2. H2O and δD profiles remotely-sensed from ground in different spectral infrared regions

    Directory of Open Access Journals (Sweden)

    F. Hase

    2010-07-01

    Full Text Available We present ground-based FTIR (Fourier transform infrared water vapour analyses performed for three different spectral regions: in the mid-infrared at 790–1330 cm−1 and 2650–3180 cm−1 as well as in the near infrared at 4560–4710 cm−1. All three analyses allow the retrieval of lower, middle, and upper tropospheric water vapour amounts with a vertical resolution of about 2, 4, and 6 km, respectively. The mid-infrared analyses allow in addition the retrieval of lower and middle/upper tropospheric δD values with a vertical resolution of 3 and 7 km, respectively. The H2O profiles retrieved in all three spectral regions show a very good agreement with coincident Vaisala RS92 radiosonde measurements performed on seven different days during the Measurements of Humidity in the Atmosphere and Validation Experiment (MOHAVE 2009 campaign. We analyse 325 ground-based FTIR spectra measured on 11 different days. For optimised line parameters we find that the 325 H2O profiles retrieved in each of the three spectral regions and the 325 δD profiles retrieved in the two mid-infrared regions agree very well. Spectroscopic parameters are the major error source for the ground-based remote sensing of δD profiles. Our inter-comparison of the two different mid-infrared spectral regions allows thus an empirical estimation of the precision of the remotely-sensed δD data of 10 and 20‰, for the lower and middle/upper troposphere, respectively.

  3. Subaru High-Dispersion Spectroscopy of Narrow-Line Region in the Seyfert Galaxy NGC 4151

    CERN Document Server

    Nagao, T; Shioya, Y; Taniguchi, Y; Nagao, Tohru; Murayama, Takashi; Shioya, Yasuhiro; Taniguchi, Yoshiaki

    2003-01-01

    We report on a study of forbidden emission-line spectrum of nearby Seyfert 1.5 galaxy NGC 4151 based on the high-resolution (R ~ 45,000) optical spectrum obtained by using the High Dispersion Spectrograph boarded on the Subaru Telescope. The profile parameters such as the emission-line widths, the velocity shifts from the recession velocity of the host galaxy, and the asymmetry indices, for emission lines including very faint ones such as [Ar IV]4712,4740 and [Fe VI]5631,5677 are investigated. Statistically significant correlations between the measured profile parameters and the critical densities of transitions are found while there are no meaningful correlations between the profile parameters and the ionization potentials of ions. By comparing the results with photoionization model calculations, we remark that a simple power-law distribution of the gas density which is independent of the radius from the nucleus cannot explain the observed correlation between the emission-line widths and the critical densiti...

  4. Using Line Profiles to Test the Fraternity of Type Ia Supernovae at High and Low Redshifts

    Science.gov (United States)

    Blondin, Stéphane; Dessart, Luc; Leibundgut, Bruno; Branch, David; Höflich, Peter; Tonry, John L.; Matheson, Thomas; Foley, Ryan J.; Chornock, Ryan; Filippenko, Alexei V.; Sollerman, Jesper; Spyromilio, Jason; Kirshner, Robert P.; Wood-Vasey, W. Michael; Clocchiatti, Alejandro; Aguilera, Claudio; Barris, Brian; Becker, Andrew C.; Challis, Peter; Covarrubias, Ricardo; Davis, Tamara M.; Garnavich, Peter; Hicken, Malcolm; Jha, Saurabh; Krisciunas, Kevin; Li, Weidong; Miceli, Anthony; Miknaitis, Gajus; Pignata, Giuliano; Prieto, Jose Luis; Rest, Armin; Riess, Adam G.; Salvo, Maria Elena; Schmidt, Brian P.; Smith, R. Chris; Stubbs, Christopher W.; Suntzeff, Nicholas B.

    2006-03-01

    Using archival data of low-redshift (zdatabases) Type Ia supernovae (SNe Ia) and recent observations of high-redshift (0.161.7] SNe Ia, which are also subluminous. In addition, we give the first direct evidence in two high-z SN Ia spectra of a double-absorption feature in Ca II λ3945, an event also observed, although infrequently, in low-redshift SN Ia spectra (6 out of 22 SNe Ia in our local sample). Moreover, echoing the recent studies of Dessart & Hillier in the context of Type II supernovae (SNe II), we see similar P Cygni line profiles in our large sample of SN Ia spectra. First, the magnitude of the velocity location at maximum profile absorption may underestimate that at the continuum photosphere, as observed, for example, in the optically thinner line S II λ5640. Second, we report for the first time the unambiguous and systematic intrinsic blueshift of peak emission of optical P Cygni line profiles in SN Ia spectra, by as much as 8000 km s-1. All the high-z SNe Ia analyzed in this paper were discovered and followed up by the ESSENCE collaboration and are now publicly available. Based in part on observations obtained at the Cerro Tololo Inter-American Observatory, which is operated by the Association of Universities for Research in Astronomy (AURA), Inc., under cooperative agreement with the National Science Foundation (NSF); the European Southern Observatory, Chile (ESO program 170.A-0519) the Gemini Observatory, which is operated by AURA under a cooperative agreement with the NSF on behalf of the Gemini partnership (the NSF [United States], the Particle Physics and Astronomy Research Council [United Kingdom], the National Research Council [Canada], CONICYT [Chile], the Australian Research Council [Australia], CNPq [Brazil], and CONICET [Argentina]) (programs GN-2002B-Q-14, GN-2003B-Q-11, and GS-2003B-Q-11) the Magellan Telescopes at Las Campanas Observatory; the MMT Observatory, a joint facility of the Smithsonian Institution and the University of

  5. Kinetic effect of high energy ions on the temperature profile in the boundary plasma region

    Energy Technology Data Exchange (ETDEWEB)

    Ezumi, N., E-mail: ezumi@nagano-nct.ac.jp [Nagano National College of Technology, 716 Tokuma, Nagano 381-8550 (Japan); Hayashi, Y.; Todoroki, K. [Nagano National College of Technology, 716 Tokuma, Nagano 381-8550 (Japan); Okazaki, K. [Graduated School of Engineering, Nagoya University, Nagoya 464-8603 (Japan); Tanaka, H.; Masuzaki, S. [National Institute for Fusion Science, Toki 509-5292 (Japan); Ohno, N. [Graduated School of Engineering, Nagoya University, Nagoya 464-8603 (Japan)

    2013-07-15

    Importance of ion dynamics in the boundary region has been discussed with experimental results of ion temperature (T{sub i}) measurements in linear plasma devices and its analytical model. Radial profiles of T{sub i} have been measured by using an ion sensitive probe in the linear devices CTP-HC and NAGDIS-II. The experiments indicate that T{sub i} is growing radially. Analytical ion-mean-energy profiles based on the ion Larmor motion are qualitatively consistent with the experimental T{sub i} profiles. These results clarify that the higher energy ions exist in the outside region of plasma flux tube.

  6. Signatures of transition region explosive events in hydrogen Ly-beta profiles

    CERN Document Server

    Zhang, M; Tian, H; Chen, Y

    2010-01-01

    We search for signatures of transition region explosive events (EEs) in hydrogen Ly-beta profiles. Two rasters made by the SUMER (Solar Ultraviolet Measurements of Emitted Radiation) instrument on board SOHO in a quiet-Sun region and an equatorial coronal hole are selected for our study. Transition region explosive events are identified from profiles of C II 1037 Angstrom and O VI 1032 Angstrom, respectively. We compare Ly-beta profiles during EEs with those averaged in the entire quiet-Sun and coronal-hole regions. The relationship between the peak emission of Ly-beta profiles and the wing emission of C II and O VI during EEs is investigated. We find that the central part of Ly-beta profiles becomes more reversed and the distance of the two peaks becomes larger during EEs, both in the coronal hole and in the quiet Sun. The average Ly-beta profile of the EEs detected by C II has an obvious stronger blue peak. During EEs, there is a clear correlation between the increased peak emission of Ly-beta profiles and ...

  7. Molecular profiling of midbrain dopamine regions in cocaine overdose victims.

    Science.gov (United States)

    Tang, Wen-Xue; Fasulo, Wendy H; Mash, Deborah C; Hemby, Scott E

    2003-05-01

    Chronic cocaine use in humans and animal models is known to lead to pronounced alterations in neuronal function in brain regions associated with drug reinforcement. To evaluate whether the alterations in gene expression in cocaine overdose victims are associated with specific dopamine populations in the midbrain, cDNA arrays and western blotting were used to compare gene and protein expression patterns between cocaine overdose victims and age-matched controls in the ventral tegmental area (VTA) and lateral substantia nigra (l-SN). Array analysis revealed significant up-regulation of numerous transcripts in the VTA, but not in the l-SN, of cocaine overdose victims including NMDAR1, GluR2, GluR5 and KA2 receptor mRNA (p overdose victims and controls were observed for GluR1, R3 or R4 mRNA levels. Correspondingly, western blot analysis revealed VTA-selective up-regulation of CREB (p cocaine overdose victims. The present results indicate that selective alterations of CREB and certain ionotropic glutamate receptor (iGluR) subtypes appear to be associated with chronic cocaine use in humans in a region-specific manner. Moreover, as subunit composition determines the functional properties of iGluRs, the observed changes may indicate alterations in the excitability of dopamine transmission underlying long-term biochemical and behavioral effects of cocaine in humans.

  8. Rapid line-profile variability of H-alpha and H-beta in the A-type shell star HD 163296

    Science.gov (United States)

    Pogodin, M. A.

    1994-02-01

    The results of the H-alpha and H-beta line profile investigation of an A0-shell star HD 163296 are presented. 47 high-resolution CCD spectra (35 for H-alpha and 12 for H-beta) were obtained on July 15-20, 1991 and on July 24-27, 1992. A considerable profile variability is found on time scales from one hour to a few days. The main properties of the night-to-night variations are strong change in shape of the entire line profile with the exception of the primary PCyg-absorption which remains relatively constant both in strength and in position. Two types of extremely rapid variations (tau approximately equal hours) are discovered: (a) positional shift of sharp spectral bumps, and (b) monotonous flux variations of different parts of a profile during a night. A qualitative explanation in the framework of the model for an envelope containing an active non-stable region formed by an equatorially concentrated stellar wind and an external cool shell is proposed for the observed variability. Some reasons for the extremely rapid profile changes are considered.

  9. Mid-Infrared [NeII] and [NeIII] Emission Line Profiles in Starbursts and AGN

    Science.gov (United States)

    Samsonyan, A. L.

    2016-09-01

    Line profiles and velocities of the [CII] 157μm line observed with the Herschel PACS instrument are compared to high resolution [NeII] 12.81μm and [NeIII] 15.55μm emission lines observed with the Spitzer Infrared Spectrograph (IRS). We are analysing spectra of at least 400 galaxies having both IRS high resolution and Herschel PACS [CII] line profiles that are available from the public archives. The goal of the work is the comparison of emission line velocity profiles and fluxes to locate and understand differences in the origins of [CII] compared to the mid-infrared Neon lines. Line velocities and widths are carefully measured, and errors are analyzed to determine if there is any kinematic evidence for [CII] arising from clouds not visible in the mid-infrared emission lines. This will give an answer to two questions: 1. Is there evidence that [CII] is more diffuse, distributed throughout galaxies, than the mid infrared starburst indicators [NeII] and [NeIII]?; 2. Is there evidence for specific, very dusty clouds of [CII] with so much extinction that the [CII] can be seen but the [NeII] and [NeIII] is not seen?

  10. Fundamental Parameter Method Applied to X-Ray Line Profile Analysis

    Directory of Open Access Journals (Sweden)

    Florica Matei

    2016-11-01

    Full Text Available Crystallite size strain effect the mechanical, electric, magnetic and optical properties of many kind of the nanomaterials. The effects of the finite crystallite size and lattice strain can be very well observed as the deformation in the shape of the X-ray line profile (XRLP. In this contribution we have used the fundamental parameter (FP [1,2] method to evaluate the nanostructure materials assuming a theoretical model of experimental XRLP.  In this contribution we have used various distribution functions such as normal, lognormal, Gumbel, Maxwell and Student. The best values of the crystallite size of nanostructued materials are chosen by analysis of root mean squares of residuals and by correlation matrix of the fit parameters. The entire procedure was implemented in the GnuPlot script.

  11. Radial velocities of giant stars: an investigation of line profile variations

    Energy Technology Data Exchange (ETDEWEB)

    Hekker, S; Snellen, I A G [Leiden Observatory, Leiden University, PO Box 9513, 2300 RA Leiden (Netherlands); Aerts, C [Instituut voor Sterrenkunde, KU Leuven, Celestijnenlaan 200D, 3001 Leuven (Belgium); Quirrenbach, A; Reffert, S [ZAH, Landessternwarte Heidelberg, Koenigstuhl 12, D-69117 Heidelberg (Germany); Mitchell, D S [California Polytechnic State University, San Luis Obispo, CA 93407 (United States)], E-mail: saskia@strw.leidenuniv.nl

    2008-10-15

    Since 1999, a radial velocity survey of 179 red giant stars is ongoing at Lick Observatory with a one month cadence. At present{approx}20-100 measurements have been collected per star with an accuracy of 5 to 8 ms{sup -1}. Of the stars monitored, 145 (80%) show radial velocity (RV) variations at a level >20 ms{sup -1}, of which 43 exhibit significant periodicities. Here, we investigate the mechanism causing the observed radial velocity variations. Firstly, we search for a correlation between the radial velocity amplitude and an intrinsic parameter of the star, in this case surface gravity (logg). Secondly, we investigate line profile variations and compare these with theoretical predictions.

  12. Multi-omic profiling of MYCN-amplified neuroblastoma cell-lines

    Directory of Open Access Journals (Sweden)

    Erik Dassi

    2015-12-01

    Full Text Available Neuroblastoma is the most common pediatric cancer, arising from the neural crest cells of the sympathetic nervous system. Its most aggressive subtype, characterized by the amplification of the MYCN oncogene, has a dismal prognosis and no effective treatment is available. Understanding the alterations induced by the tumor on the various layers of gene expression is therefore important for a complete characterization of this neuroblastoma subtype and for the discovery of new therapeutic opportunities. Here we describe the profiling of 13 MYCN-amplified neuroblastoma cell lines at the genome (copy number, transcriptome, translatome and miRome levels (GEO series GSE56654, GSE56552 and GSE56655. We provide detailed experimental and data analysis procedures by means of which we derived the results described in [1].

  13. Chemical and Antimicrobial Profiling of Propolis from Different Regions within Libya.

    Directory of Open Access Journals (Sweden)

    Weam Siheri

    Full Text Available Extracts from twelve samples of propolis collected from different regions of Libya were tested for their activity against Trypanosoma brucei, Leishmania donovani, Plasmodium falciparum, Crithidia fasciculata and Mycobacterium marinum and the cytotoxicity of the extracts was tested against mammalian cells. All the extracts were active to some degree against all of the protozoa and the mycobacterium, exhibiting a range of EC50 values between 1.65 and 53.6 μg/ml. The toxicity against mammalian cell lines was only moderate; the most active extract against the protozoan species, P2, displayed an IC50 value of 53.2 μg/ml. The extracts were profiled by using liquid chromatography coupled to high resolution mass spectrometry. The data sets were extracted using m/z Mine and the accurate masses of the features extracted were searched against the Dictionary of Natural Products (DNP. A principal component analysis (PCA model was constructed which, in combination with hierarchical cluster analysis (HCA, divided the samples into five groups. The outlying groups had different sets of dominant compounds in the extracts, which could be characterised by their elemental composition. Orthogonal partial least squares (OPLS analysis was used to link the activity of each extract against the different micro-organisms to particular components in the extracts.

  14. Effect of a partial coverage of quasar broad-line regions by intervening H$_2$-bearing clouds

    CERN Document Server

    Ofengeim, Dmitrii; Ivanchik, Aleksandr; Kaminker, Aleksandr; Klimenko, Vyacheslav

    2015-01-01

    We consider the effect of a partial coverage of quasar broad-line regions (QSO BLRs) by intervening H$_2$-bearing clouds when a part of quasar (QSO) radiation passes by a cloud not taking part in formation of an absorption-line system in the QSO spectrum. That leads to modification of observable absorption line profiles and consequently to a bias in physical parameters derived from standard absorption line analysis. In application to the H$_2$ {absorption} systems the effect has been revealed in the analysis of H$_2$ absorption system in the spectrum of Q~1232+082 (Ivanchik et al. 2010, Balashev et al. 2011). We estimate a probability of the effect to be detected in QSO spectra. To do this we derive distribution of BLR sizes of high-z QSOs from Sloan Digital Sky Survey (SDSS) Data Release 9 (DR9) catalogue and assume different distributions of cloud sizes. We conclude that the low limit of the probability is about $11\\%$. The latest researches shows that about a fifth of observed H$_2$ absorption systems can ...

  15. Spectral-Line Survey at Millimeter and Submillimeter Wavelengths toward an Outflow-Shocked Region, OMC 2-FIR 4

    CERN Document Server

    Shimajiri, Yoshito; Kitamura, Yoshimi; Tsukagoshi, Takashi; Saito, Masao; Nakamura, Fumitaka; Momose, Munetake; Takakuwa, Shigehisa; Yamaguchi, Takahiro; Sakai, Nami; Yamamoto, Satoshi; Kawabe, Ryohei

    2015-01-01

    We performed the first spectral-line survey at 82--106 GHz and 335--355 GHz toward the outflow-shocked region, OMC 2-FIR 4, the outflow driving source, FIR 3, and the northern outflow lobe, FIR 3N. We detected 120 lines of 20 molecular species. The line profiles are found to be classifiable into two types: one is a single Gaussian component with a narrow ($$ 3km s$^{-1}$) widths. The narrow components for the most of the lines are detected at all positions, suggesting that they trace the ambient dense gas. For CO, CS, HCN, and HCO$^{+}$, the wide components are detected at all positions, suggesting the outflow origin. The wide components of C$^{34}$S, SO, SiO, H$^{13}$CN, HC$^{15}$N, H$_2^{13}$CO, H$_2$CS, HC$_3$N, and CH$_3$OH are detected only at FIR 4, suggesting the outflow-shocked gas origin. The rotation diagram analysis revealed that the narrow components of C$_2$H and H$^{13}$CO$^+$ show low temperatures of 12.5$\\pm$1.4 K, while the wide components show high temperatures of 20--70 K. This supports our...

  16. Untangling the Recombination Line Emission from HII Regions with Multiple Velocity Components

    CERN Document Server

    Anderson, L D; Wenger, T V; Bania, T M; Balser, Dana S

    2015-01-01

    HII regions are the ionized spheres surrounding high-mass stars. They are ideal targets for tracing Galactic structure because they are predominantly found in spiral arms and have high luminosities at infrared and radio wavelengths. In the Green Bank Telescope HII Region Discovery Survey (GBT HRDS) we found that >30% of first Galactic quadrant HII regions have multiple hydrogen radio recombination line (RRL) velocities, which makes determining their Galactic locations and physical properties impossible. Here we make additional GBT RRL observations to determine the discrete HII region velocity for all 117 multiple-velocity sources within 18deg. < l < 65deg. The multiple-velocity sources are concentrated in the zone 22deg. < l < 32deg., coinciding with the largest regions of massive star formation, which implies that the diffuse emission is caused by leaked ionizing photons. We combine our observations with analyses of the electron temperature, molecular gas, and carbon recombination lines to determ...

  17. Social Profiles and Social Behaviour and Attitudes towards Gaming and On-Line Gaming in Spain

    Directory of Open Access Journals (Sweden)

    Francisco Javier RUIZ MARTÍNEZ

    2011-12-01

    Full Text Available For the last two decades our world has experienced increasing globalization linked to the revolution in Information and Communication Technologies (ICT leading to new business spheres escaping from the traditional Nation-State control. The gaming business is one of these areas and has recorded a notable increase in profits in the last decade: gambling, betting and network games constitute some of the main issues developed by ICT companies located beyond State control. The action of the States is focusing on the formulation of new public policies that allow them to control these activities. But first a deep social description of gaming is needed to know which actors are involved in this field of activities, which is the profile of the gamer and what kind of social attitudes are carried out by users and companies taking part of the business. This article focuses on the social profiles and the social behaviour and attitudes towards gaming in Spain, and specially in the transition from traditional gaming to on line gaming.

  18. Observations and simulations of the Na I D1 line profiles in an M-class solar flare

    CERN Document Server

    Kuridze, D; Christian, D J; Kowalski, A F; Jess, D B; Grant, S D T; Kawate, T; Simões, P J A; Allred, J C; Keenan, F P

    2016-01-01

    We study the temporal evolution of the Na I D1 line profiles in the M3.9 flare SOL2014-06-11T21:03 UT, using high spectral resolution observations obtained with the IBIS instrument on the Dunn Solar Telescope combined with radiative hydrodynamic simulations. Our results show a significant increase in line core and wing intensities during the flare. The analysis of the line profiles from the flare ribbons reveal that the Na I D1 line has a central reversal with excess emission in the blue wing (blue asymmetry). We combine RADYN and RH simulations to synthesise Na I D1 line profiles of the flaring atmosphere and find good agreement with the observations. Heating with a beam of electrons modifies the radiation field in the flaring atmosphere and excites electrons from the ground state $\\mathrm{3s~^2S}$ to the first excited state $\\mathrm{3p~^2P}$, which in turn modifies relative population of the two states. The change in temperature and the population density of the energy states make the sodium line profile re...

  19. A search for non-hidden broad-line region Seyfert 2 galaxies

    CERN Document Server

    Petrov, Georgi P

    2016-01-01

    According to the unified model of active galactic nuclei, Seyfert 2 galaxies are physically the same as Seyfert 1 objects and they possess a broad-line region (BLR), but it is hidden from the observer due to their orientation. In the past few years, various authors reported that not all Seyfert 2 galaxies harbor a BLR. We compiled a sample of 38 Seyfert 2 galaxies to find non-hidden broad-line region (non-HBLR) objects. Using the theory of Nicastro et al. which suggests the existence of a critical value of the Eddington ratio below which BLR can't be formed, we found 26 non-HBLR Seyfert 2 candidates. We found also that 5 of these 26 non-HBLR objects could be low-ionization nuclear emission-line regions (LINERs).

  20. Extracellular matrix proteins expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line.

    Science.gov (United States)

    Januchowski, Radosław; Zawierucha, Piotr; Ruciński, Marcin; Nowicki, Michał; Zabel, Maciej

    2014-01-01

    Ovarian cancer is the leading cause of death among gynaecological malignancies. Extracellular matrix (ECM) can affect drug resistance by preventing the penetration of the drug into cancer cells and increased resistance to apoptosis. This study demonstrates alterations in the expression levels of ECM components and related genes in cisplatin-, doxorubicin-, topotecan-, and paclitaxel-resistant variants of the A2780 ovarian cancer cell line. Affymetrix Gene Chip Human Genome Array Strips were used for hybridisations. The genes that had altered expression levels in drug-resistant sublines were selected and filtered by scatter plots. The genes that were up- or downregulated more than fivefold were selected and listed. Among the investigated genes, 28 genes were upregulated, 10 genes were downregulated, and two genes were down- or upregulated depending on the cell line. Between upregulated genes 12 were upregulated very significantly--over 20-fold. These genes included COL1A2, COL12A1, COL21A1, LOX, TGFBI, LAMB1, EFEMP1, GPC3, SDC2, MGP, MMP3, and TIMP3. Four genes were very significantly downregulated: COL11A1, LAMA2, GPC6, and LUM. The expression profiles of investigated genes provide a preliminary insight into the relationship between drug resistance and the expression of ECM components. Identifying correlations between investigated genes and drug resistance will require further analysis.

  1. Gene Expression Profile of Multiple Myeloma Cell Line Treated by Arsenic Trioxide

    Institute of Scientific and Technical Information of China (English)

    WANG Mengchang; LIU Shaanxi; LIU Pengbo

    2007-01-01

    cDNA microarray was used to compare the gone expression profiles of multiple myeloma cell line RPMI8226 24 h before and after treatment with arsenic trioxide. Two eDNA probes were prepared by mRNA reverse transcription of both arsenic trioxide-treated and untreated RPMI8226 cells. The probes were labeled with Cy3 and Cy5 fluorescence dyes separately, hybridized with cDNA microarray representing 4096 different human genes, and scanned for fluorescence intensity. The differences in gene expression were calculated on the basis of the ratios of signal intensity of treated and untreated samples. The up- and down-regulated genes were screened through the analysis of gene expression ratios. The results showed that 273 genes were differentially altered at mRNA level, 121 genes were up-regulated and 152 were down-regulated. It is concluded that the treatment with arsenic trioxide can induce a variety of gene changes in RPMI8226 cell line. Many genes may be involved in the pathogenesis of multiple myeloma. ALK-1 and TXNIP genes may play an impor- tant role in the apoptosis and partial differentiation of RPMI8226 cells.

  2. The Lick AGN Monitoring Project: Broad-line Region Radii and Black Hole Masses from Reverberation Mapping of Hβ

    Science.gov (United States)

    Bentz, Misty C.; Walsh, Jonelle L.; Barth, Aaron J.; Baliber, Nairn; Bennert, Vardha Nicola; Canalizo, Gabriela; Filippenko, Alexei V.; Ganeshalingam, Mohan; Gates, Elinor L.; Greene, Jenny E.; Hidas, Marton G.; Hiner, Kyle D.; Lee, Nicholas; Li, Weidong; Malkan, Matthew A.; Minezaki, Takeo; Sakata, Yu; Serduke, Frank J. D.; Silverman, Jeffrey M.; Steele, Thea N.; Stern, Daniel; Street, Rachel A.; Thornton, Carol E.; Treu, Tommaso; Wang, Xiaofeng; Woo, Jong-Hak; Yoshii, Yuzuru

    2009-11-01

    We have recently completed a 64-night spectroscopic monitoring campaign at the Lick Observatory 3-m Shane telescope with the aim of measuring the masses of the black holes in 12 nearby (z measured between the continuum fluctuations and the response to these fluctuations in the broad Hβ emission. We present here the light curves for all the objects in this sample and the subsequent Hβ time lags for the nine objects where these measurements were possible. The Hβ lag time is directly related to the size of the broad-line region (BLR) in AGNs, and by combining the Hβ lag time with the measured width of the Hβ emission line in the variable part of the spectrum, we determine the virial mass of the central supermassive black hole in these nine AGNs. The absolute calibration of the black hole masses is based on the normalization derived by Onken et al., which brings the masses determined by reverberation mapping into agreement with the local M BH-σsstarfrelationship for quiescent galaxies. We also examine the time lag response as a function of velocity across the Hβ line profile for six of the AGNs. The analysis of four leads to rather ambiguous results with relatively flat time lags as a function of velocity. However, SBS 1116+583A exhibits a symmetric time lag response around the line center reminiscent of simple models for circularly orbiting BLR clouds, and Arp 151 shows an asymmetric profile that is most easily explained by a simple gravitational infall model. Further investigation will be necessary to fully understand the constraints placed on the physical models of the BLR by the velocity-resolved response in these objects.

  3. The Sagittarius B2 star-forming region - Subarcsecond radio spectral line and continuum observations

    Energy Technology Data Exchange (ETDEWEB)

    Gaume, R.A.; Claussen, M.J. (E. O. Hulburt Center for Space Research, Washington, DC (USA))

    1990-03-01

    Results are reported of a subarcsecond spatial resolution RF line and continuum study of the Sgr B2 region, observed at the frequency of the 76-alpha hydrogen recombination line and at the (J,K = 3,2) transition of NH3. Also reported are new observations of the ground-state OH main line masers toward Sgr B2 in both left and right circular polarization. The continuum images showed no less than 19 separate H II regions in the Sgr B2 complex. Ammonia emission was observed in the Sgr B2 K and F regions. The emission toward K was found near the K1, K2, and K3 regions. The NH3 emission and absorption toward the F region, along with the OH maser emission, delineate a rotating disk or torus of molecular material surrounding the Sgr B2 F complex of H II regions. The mass interior to the NH3 and OH emission regions was calculated to be on the order of 1400 solar masses. 38 refs.

  4. Modelling Carbon Radio Recombination Line observation towards the Ultra-Compact HII region W48A

    CERN Document Server

    Jeyakumar, S

    2013-01-01

    We model Carbon Recombination Line (CRL) emission from the Photo Dissociation Region (PDR) surrounding the Ultra-Compact (UC) HII region W48A. Our modelling shows that the inner regions ($A_V \\sim 1$) of the CII layer in the PDR contribute significantly to the CRL emission. The dependence of line ratios of CRL emission with the density of the PDR and the far ultra-violet (FUV) radiation incident on the region is explored over a large range of these parameters that are typical for the environments of UCHII regions. We find that by observing a suitable set of CRLs it is possible to constrain the density of the PDR. If the neutral density in the PDR is high ($\\gtrsim 10^7$ \\cmthree) CRL emission is bright at high frequencies ($\\gtrsim 20$ GHz), and absorption lines from such regions can be detected at low frequencies ($\\lesssim 10$ GHz). Modelling CRL observations towards W48A shows that the UCHII region is embedded in a molecular cloud of density of about $4 \\times$ 10$^7$ \\cmthree.

  5. H2 infrared line emission from the ionized region of planetary nebulae

    CERN Document Server

    Aleman, Isabel

    2010-01-01

    The analysis and interpretation of the H2 line emission from planetary nebulae have been done in the literature assuming that the molecule survives only in regions where the hydrogen is neutral, as in photodissociation, neutral clumps or shocked regions. However, there is strong observational and theoretical evidence that at least part of the H2 emission is produced inside the ionized region of such objects. The aim of the present work is to calculate and analyze the infrared line emission of H2 produced inside the ionized region of planetary nebulae using a one-dimensional photoionization code. The photoionization code Aangaba was improved in order to calculate the statistical population of the H2 energy levels and the intensity of the H2 infrared emission lines in physical conditions typical of planetary nebulae. A grid of models was obtained and the results are analyzed and compared with the observational data. We show that the contribution of the ionized region to the H2 line emission can be important, pa...

  6. Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.

    Directory of Open Access Journals (Sweden)

    Jessica Kao

    Full Text Available BACKGROUND: Breast cancer cell lines have been used widely to investigate breast cancer pathobiology and new therapies. Breast cancer is a molecularly heterogeneous disease, and it is important to understand how well and which cell lines best model that diversity. In particular, microarray studies have identified molecular subtypes-luminal A, luminal B, ERBB2-associated, basal-like and normal-like-with characteristic gene-expression patterns and underlying DNA copy number alterations (CNAs. Here, we studied a collection of breast cancer cell lines to catalog molecular profiles and to assess their relation to breast cancer subtypes. METHODS: Whole-genome DNA microarrays were used to profile gene expression and CNAs in a collection of 52 widely-used breast cancer cell lines, and comparisons were made to existing profiles of primary breast tumors. Hierarchical clustering was used to identify gene-expression subtypes, and Gene Set Enrichment Analysis (GSEA to discover biological features of those subtypes. Genomic and transcriptional profiles were integrated to discover within high-amplitude CNAs candidate cancer genes with coordinately altered gene copy number and expression. FINDINGS: Transcriptional profiling of breast cancer cell lines identified one luminal and two basal-like (A and B subtypes. Luminal lines displayed an estrogen receptor (ER signature and resembled luminal-A/B tumors, basal-A lines were associated with ETS-pathway and BRCA1 signatures and resembled basal-like tumors, and basal-B lines displayed mesenchymal and stem/progenitor-cell characteristics. Compared to tumors, cell lines exhibited similar patterns of CNA, but an overall higher complexity of CNA (genetically simple luminal-A tumors were not represented, and only partial conservation of subtype-specific CNAs. We identified 80 high-level DNA amplifications and 13 multi-copy deletions, and the resident genes with concomitantly altered gene-expression, highlighting known and

  7. DETECTION OF THE INTERMEDIATE-WIDTH EMISSION LINE REGION IN QUASAR OI 287 WITH THE BROAD EMISSION LINE REGION OBSCURED BY THE DUSTY TORUS

    Energy Technology Data Exchange (ETDEWEB)

    Li, Zhenzhen; Zhou, Hongyan; Wang, Huiyuan; Liu, Bo; Liu, Wen-Juan; Pan, Xiang; Jiang, Peng [Department of Astronomy, University of Science and Technology of China, Hefei, Anhui 230026 (China); Hao, Lei [Key Laboratory for Research in Galaxies and Cosmology, Shanghai Astronomical Observatory, Chinese Academy of Sciences, 80 Nandan Road, Shanghai 200030 (China); Ji, Tuo; Shi, Xiheng; Zhang, Shaohua, E-mail: lizz08@mail.ustc.edu.cn, E-mail: zhouhongyan@pric.org.cn, E-mail: haol@shao.ac.cn [Polar Research Institute of China, Jinqiao Rd. 451, Shanghai, 200136 (China)

    2015-10-20

    The existence of intermediate-width emission line regions (IELRs) in active galactic nuclei has been discussed for over two decades. A consensus, however, is yet to be arrived at due to the lack of convincing evidence for their detection. We present a detailed analysis of the broadband spectrophotometry of the partially obscured quasar OI 287. The ultraviolet intermediate-width emission lines (IELs) are very prominent, in high contrast to the corresponding broad emission lines (BELs) which are heavily suppressed by dust reddening. Assuming that the IELR is virialized, we estimated its distance to the central black hole to be ∼2.9 pc, similar to the dust sublimation radius of ∼1.3 pc. Photo-ionization calculations suggest that the IELR has a hydrogen density of ∼10{sup 8.8}–10{sup 9.4} cm{sup −3}, within the range of values quoted for the dusty torus near the sublimation radius. Both its inferred location and physical conditions suggest that the IELR originates from the inner surface of the dusty torus. In the spectrum of this quasar, we identified only one narrow absorption-line system associated with the dusty material. With the aid of photo-ionization model calculations, we found that the obscuring material might originate from an outer region of the dusty torus. We speculate that the dusty torus, which is exposed to the central ionizing source, may produce IELs through photo-ionization processes, as well as obscure BELs as a natural “coronagraph.” Such a “coronagraph” could be found in a large number of partially obscured quasars and may be a useful tool to study IELRs.

  8. Caustics and Caustic-Diffraction in Laser Shadowgraphy of a Sessile Drop and Identification of Profile Near Contact Line

    Science.gov (United States)

    Zhang, Neng-Li; Chao, David F.

    2003-01-01

    This paper presents an optical method based on the caustics and caustic-difraction in laser shadowgaphy of a sessile drop to identify and estimate the drop profile near the contact line. A parallel laser beam passes through a liquid sessile drop placed on a transparent substrate to produce a shadowgraphic image of the drop on the screen far from the substrate. Along the inflection line of the drop the Gaussian curvature of the wavefront deformed by the drop vanishes, and therefore the inflection line gives caustics in the far field of the wave, which can be seen on the screen. The neighboring light rays at both sides of the inflection line interfere with each other to form interference fringes at the inner side of the caustics. According to the pattern of the caustics, the drop-profile shape can be identified and estimated.

  9. The morphologies of breast cancer cell lines in three-dimensionalassays correlate with their profiles of gene expression

    Energy Technology Data Exchange (ETDEWEB)

    Kenny, Paraic A.; Lee, Genee Y.; Myers, Connie A.; Neve, RichardM.; Semeiks, Jeremy R.; Spellman, Paul T.; Lorenz, Katrin; Lee, Eva H.; Barcellos-Hoff, Mary Helen; Petersen, Ole W.; Gray, Joe W.; Bissell, MinaJ.

    2007-01-31

    3D cell cultures are rapidly becoming the method of choice for the physiologically relevant modeling of many aspects of non-malignant and malignant cell behavior ex vivo. Nevertheless, only a limited number of distinct cell types have been evaluated in this assay to date. Here we report the first large scale comparison of the transcriptional profiles and 3D cell culture phenotypes of a substantial panel of human breast cancer cell lines. Each cell line adopts a colony morphology of one of four main classes in 3D culture. These morphologies reflect, at least in part, the underlying gene expression profile and protein expression patterns of the cell lines, and distinct morphologies were also associated with tumor cell invasiveness and with cell lines originating from metastases. We further demonstrate that consistent differences in genes encoding signal transduction proteins emerge when even tumor cells are cultured in 3D microenvironments.

  10. Diagnostic Power of Broad Emission Line Profiles in Searches for Binary Supermassive Black Holes: Comparison of Models with Observations

    Science.gov (United States)

    Nguyen, Khai; Bogdanovic, Tamara; Eracleous, Michael; Runnoe, Jessie C.; Sigurdsson, Steinn

    2017-01-01

    Motivated by observational searches for sub-parsec supermassive black hole binaries (SBHBs) we develop a semi-analytic model to describe the spectral emission line signatures of these systems. We are particularly interested in modeling the profiles of the broad emission lines, which have been used as a tool to search for SBHBs. The goal of this work is to test one of the leading models of binary accretion flows in the literature: SBHB in a circumbinary disk. In this context, we model SBHB accretion flows as a set of three accretion disks: two mini-disks that are gravitationally bound to the individual black holes and a circumbinary disk that forms a common envelope about a gravitationally bound binary. Our first generation model shows that emission line profiles tend to have different statistical properties depending on the semi-major axis, mass ratio, eccentricity of the binary, and the alignment of the triple-disk system, and can in principle be used to constrain the statistical distribution of these parameters. We present the results of a second generation model, which improves upon the treatment of radiative transfer by taking into account the effect of line-driven winds on the properties of the model emission line profiles. This improvement allows a preliminary comparison of the model profiles with the observed SBHB candidates and AGN population in general.

  11. Physiological basis and transcriptional profiling of three salt-tolerant mutant lines of rice

    Directory of Open Access Journals (Sweden)

    Concha Domingo

    2016-09-01

    Full Text Available Salinity is a complex trait that affects growth and productivity in many crops, including rice. Mutation induction, a useful tool to generate salt tolerant plants, enables the analysis of plants with similar genetic background, facilitating the understanding of the salt tolerance mechanisms. In this work, we generated three salt tolerant mutant lines by irradiation of a salt-sensitive cultivar plants and screened M2 plants at seedling stage in the presence of high salinity. These three lines, SaT20, SaS62 and SaT58, showed different responses to salinity, but exhibited similar phenotype to wild type plants, except SaT20 that displayed shorter height when grown in the absence of salt. Under salt conditions, all three mutants and the parental line showed similar reduction in yield, although relevant differences in other physiological parameters, such as Na+ accumulation in healthy leaves of SaT20, were registered. Microarray analyses of gene expression profiles in roots revealed the occurrence of common and specific responses in the mutants. The three mutants showed up-regulation of responsive genes, the activation of oxido-reduction process and the inhibition of ion transport. The participation of jasmonate in the plant response to salt was evident by down-regulation of a gene coding for a jasmonate O-methyltransferase. Genes dealing with lipid transport and metabolism were, in general, up-regulated except in SaS62, that also exhibited down-regulation of genes involved in ion transport and Ca2+ signal transduction. The two most tolerant varieties, SaS62 and SaT20, displayed lower levels of transcripts involved in K+ uptake. The physiological study and the description of the expression analysis evidenced that the three lines showed different responses to salt: SaT20 showed a high Na+ content in leaves, SaS62 presented an inhibition of lipid metabolism and ion transport and SaT58 differs in both features in the response to salinity. The analysis of

  12. Integrative fitting of absorption line profiles with high accuracy, robustness, and speed

    Science.gov (United States)

    Skrotzki, Julian; Habig, Jan Christoph; Ebert, Volker

    2014-08-01

    The principle of the integrative evaluation of absorption line profiles relies on the numeric integration of absorption line signals to retrieve absorber concentrations, e.g., of trace gases. Thus, it is a fast and robust technique. However, previous implementations of the integrative evaluation principle showed shortcomings in terms of accuracy and the lack of a fit quality indicator. This has motivated the development of an advanced integrative (AI) fitting algorithm. The AI fitting algorithm retains the advantages of previous integrative implementations—robustness and speed—and is able to achieve high accuracy by introduction of a novel iterative fitting process. A comparison of the AI fitting algorithm with the widely used Levenberg-Marquardt (LM) fitting algorithm indicates that the AI algorithm has advantages in terms of robustness due to its independence from appropriately chosen start values for the initialization of the fitting process. In addition, the AI fitting algorithm shows speed advantages typically resulting in a factor of three to four shorter computational times on a standard personal computer. The LM algorithm on the other hand retains advantages in terms of a much higher flexibility, as the AI fitting algorithm is restricted to the evaluation of single absorption lines with precomputed line width. Comparing both fitting algorithms for the specific application of in situ laser hygrometry at 1,370 nm using direct tunable diode laser absorption spectroscopy (TDLAS) suggests that the accuracy of the AI algorithm is equivalent to that of the LM algorithm. For example, a signal-to-noise ratio of 80 and better typically yields a deviation of TDLAS hygrometry at the aerosol and cloud chamber aerosol interactions and dynamics in the atmosphere (AIDA)—a unique large-scale facility to study atmospheric processes. The robustness of the AI fitting algorithm has been validated for typical AIDA conditions encompassing strong transmission fluctuations

  13. Physiological Basis and Transcriptional Profiling of Three Salt-Tolerant Mutant Lines of Rice

    Science.gov (United States)

    Domingo, Concha; Lalanne, Eric; Catalá, María M.; Pla, Eva; Reig-Valiente, Juan L.; Talón, Manuel

    2016-01-01

    Salinity is a complex trait that affects growth and productivity in many crops, including rice. Mutation induction, a useful tool to generate salt tolerant plants, enables the analysis of plants with similar genetic background, facilitating the understanding of the salt tolerance mechanisms. In this work, we generated three salt tolerant mutant lines by irradiation of a salt-sensitive cultivar plants and screened M2 plants at seedling stage in the presence of high salinity. These three lines, SaT20, SaS62, and SaT58, showed different responses to salinity, but exhibited similar phenotype to wild type plants, except SaT20 that displayed shorter height when grown in the absence of salt. Under salt conditions, all three mutants and the parental line showed similar reduction in yield, although relevant differences in other physiological parameters, such as Na+ accumulation in healthy leaves of SaT20, were registered. Microarray analyses of gene expression profiles in roots revealed the occurrence of common and specific responses in the mutants. The three mutants showed up-regulation of responsive genes, the activation of oxido-reduction process and the inhibition of ion transport. The participation of jasmonate in the plant response to salt was evident by down-regulation of a gene coding for a jasmonate O-methyltransferase. Genes dealing with lipid transport and metabolism were, in general, up-regulated except in SaS62, that also exhibited down-regulation of genes involved in ion transport and Ca2+ signal transduction. The two most tolerant varieties, SaS62 and SaT20, displayed lower levels of transcripts involved in K+ uptake. The physiological study and the description of the expression analysis evidenced that the three lines showed different responses to salt: SaT20 showed a high Na+ content in leaves, SaS62 presented an inhibition of lipid metabolism and ion transport and SaT58 differs in both features in the response to salinity. The analysis of these salt

  14. Broader utilization of origins of DNA replication in cancer cell lines along a 78 kb region of human chromosome 2q34.

    Science.gov (United States)

    Valenzuela, Manuel S; Hu, Lan; Lueders, John; Walker, Robert; Meltzer, Paul S

    2012-01-01

    Human DNA replication depends on the activation of thousands of origins distributed within the genome. The actual distribution of origins is not known, nor whether this distribution is unique to a cell type, or if it changes with the proliferative state of the cell. In this study, we have employed a real-time PCR-based nascent strand DNA abundance assay, to determine the location of origins along a 78 kb region on Chr2q34. Preliminary studies using nascent DNA strands isolated from either HeLa and normal skin fibroblast cells showed that in both cell lines peaks of high origin activity mapped in similar locations. However, the overall origin profile in HeLa cells corresponded to broad origin activation zones, whereas in fibroblasts a more punctuated profile of origin activation was observed. To investigate the relevance of this differential origin profile, we compared the origin distribution profiles in breast cancer cell lines MDA-MB-231, BT-474, and MCF-7, to their normal counterpart MCF-10A. In addition, the CRL7250 cell line was also used as a normal control. Our results validated our earlier observation and showed that the origin profile in normal cell lines exhibited a punctuated pattern, in contrast to broader zone profiles observed in the cancer cell lines. A quantitative analysis of origin peaks revealed that the number of activated origins in cancer cells is statistically larger than that obtained in normal cells, suggesting that the flexibility of origin usage is significantly increased in cancer cells compared to their normal counterparts.

  15. Optical Recombination Lines of Heavy-elements in Giant Extragalactic HII Regions

    CERN Document Server

    Esteban, C; Torres-Peimbert, S; Rodríguez, M

    2002-01-01

    We present high resolution observations of the giant extragalactic H II regions NGC 604, NGC 2363, NGC 5461 and NGC 5471, based on observations taken with the ISIS spectrograph on the William Herschel Telescope. We have detected -by the first time- C II and O II recombination lines in these objects. We find that recombination lines give larger C^{++} and O^{++} abundances than collisionallly excited lines, suggesting that temperature variations can be present in the objects. We detect [Fe IV] lines in NGC 2363 and NGC 5471, the most confident detection of optical lines of this kind in H II regions. Considering the temperature structure we derive their H, He, C, N, O, Ne, S, Ar, and Fe abundances. From the recombination lines of NGC 5461 and NGC 5471 we determine the presence of C/H and O/H gradients in M101. We calculate the Delta Y/Delta O and Delta Y/Delta Z values considering the presence of temperature variations and under the assumption of constant temperature. We obtain a better agreement with models of...

  16. Spectral-line Survey at Millimeter and Submillimeter Wavelengths toward an Outflow-shocked Region, OMC 2-FIR 4

    Science.gov (United States)

    Shimajiri, Yoshito; Sakai, Takeshi; Kitamura, Yoshimi; Tsukagoshi, Takashi; Saito, Masao; Nakamura, Fumitaka; Momose, Munetake; Takakuwa, Shigehisa; Yamaguchi, Takahiro; Sakai, Nami; Yamamoto, Satoshi; Kawabe, Ryohei

    2015-12-01

    We performed the first spectral line survey at 82-106 GHz and 335-355 GHz toward the outflow-shocked region OMC 2-FIR 4, the outflow driving source FIR 3, and the northern outflow lobe FIR 3N. We detected 120 lines of 20 molecular species. The line profiles can be classified into two types: one type is a single Gaussian component with a narrow (3 km s-1) widths. The narrow components for most of the lines are detected at all positions, suggesting that they trace the ambient dense gas. For CO, CS, HCN, and HCO+, the wide components are detected at all positions, suggesting an outflow origin. The wide components of C34S, SO, SiO, H13CN, HC15N, {{{H}}}213CO, H2CS, HC3N, and CH3OH are only detected at FIR 4, suggesting an origin as outflow-shocked gas. The rotation diagram analysis revealed that the narrow components of C2H and H13CO+ show low temperatures of 12.5 ± 1.4 K, while the wide components show high temperatures of 20-70 K. This supports our interpretation that the wide components trace the outflow and/or outflow-shocked gas. We compared the observed molecular abundances relative to H13CO+ with those of the outflow-shocked region L 1157 B1 and the hot corino IRAS 16293-2422. Although we cannot exclude the possibility that the chemical enrichment in FIR 4 is caused by hot-core chemistry, the chemical compositions in FIR 4 are more similar to those in L 1157 B1 than those in IRAS 16293-2422.

  17. Kinetic signatures of the region surrounding the X line in asymmetric (magnetopause) reconnection

    Science.gov (United States)

    Shay, M. A.; Phan, T. D.; Haggerty, C. C.; Fujimoto, M.; Drake, J. F.; Malakit, K.; Cassak, P. A.; Swisdak, M.

    2016-05-01

    Kinetic particle-in-cell simulations are used to identify signatures of the electron diffusion region (EDR) and its surroundings during asymmetric magnetic reconnection. A "shoulder" in the sunward pointing normal electric field (EN > 0) at the reconnection magnetic field reversal is a good indicator of the EDR and is caused by magnetosheath electron meandering orbits in the vicinity of the X line. Earthward of the X line, electrons accelerated by EN form strong currents and crescent-shaped distribution functions in the plane perpendicular to B. Just downstream of the X line, parallel electric fields create field-aligned crescent electron distribution functions. In the immediate upstream magnetosheath, magnetic field strength, plasma density, and perpendicular electron temperatures are lower than the asymptotic state. In the magnetosphere inflow region, magnetosheath ions intrude resulting in an Earthward pointing electric field and parallel heating of magnetospheric particles. Many of the above properties persist with a guide field of at least unity.

  18. Kinetic signatures of the region surrounding the X-line in asymmetric (magnetopause) reconnection

    CERN Document Server

    Shay, M A; Haggerty, C C; Fujimoto, M; Drake, J F; Malakit, K; Cassak, P A; Swisdak, M

    2016-01-01

    Kinetic particle-in-cell simulations are used to identify signatures of the electron diffusion region (EDR) and its surroundings during asymmetric magnetic reconnection. A "shoulder" in the sunward pointing normal electric field (EN > 0) at the reconnection magnetic field reversal is a good indicator of the EDR, and is caused by magnetosheath electron meandering orbits in the vicinity of the x-line. Earthward of the X-line, electrons accelerated by EN form strong currents and crescent-shaped distribution functions in the plane perpendicular to B. Just downstream of the X-line, parallel electric fields create field-aligned crescent electron distribution functions. In the immediate upstream magnetosheath, magnetic field strength, plasma density, and perpendicular electron temperatures are lower than the asymptotic state. In the magnetosphere inflow region, magnetosheath ions intrude resulting in an Earthward pointing electric field and parallel heating of magnetospheric particles. Many of the above properties p...

  19. Gene expression profiles deciphering leaf senescence variation between early- and late-senescence cotton lines.

    Directory of Open Access Journals (Sweden)

    Xiangqiang Kong

    Full Text Available Leaf senescence varies greatly among genotypes of cotton (Gossypium hirsutium L, possibly due to the different expression of senescence-related genes. To determine genes involved in leaf senescence, we performed genome-wide transcriptional profiling of the main-stem leaves of an early- (K1 and a late-senescence (K2 cotton line at 110 day after planting (DAP using the Solexa technology. The profiling analysis indicated that 1132 genes were up-regulated and 455 genes down-regulated in K1 compared with K2 at 110 DAP. The Solexa data were highly consistent with, and thus were validated by those from real-time quantitative PCR (RT-PCR. Most of the genes related to photosynthesis, anabolism of carbohydrates and other biomolecules were down-regulated, but those for catabolism of proteins, nucleic acids, lipids and nutrient recycling were mostly up-regulated in K1 compared with K2. Fifty-one differently expressed hormone-related genes were identified, of which 5 ethylene, 3 brassinosteroid (BR, 5 JA, 18 auxin, 8 GA and 1 ABA related genes were up-regulated in K1 compared with K2, indicating that these hormone-related genes might play crucial roles in early senescence of K1 leaves. Many differently expressed transcription factor (TF genes were identified and 11 NAC and 8 WRKY TF genes were up-regulated in K1 compared with K2, suggesting that TF genes, especially NAC and WRKY genes were involved in early senescence of K1 leaves. Genotypic variation in leaf senescence was attributed to differently expressed genes, particularly hormone-related and TF genes.

  20. Heavy elements in Galactic and Magellanic Cloud HII regions recombination-line versus forbidden-line abundances

    CERN Document Server

    Tsamis, Y G; Liu, X W; Danziger, I J; Storey, P J; Tsamis, Yiannis G.

    2003-01-01

    We have obtained deep optical, long-slit spectrophotometry of the Galactic HII regions M 17, NGC 3576 and of the Magellanic Cloud HII regions 30 Doradus, LMC N11B and SMC N66, recording the optical recombination lines (ORLs) of CII, NII and OII. Temperature-insensitive ORL C2+/O2+ and N2+/O2 ratios are obtained for all nebulae except SMC N66. The ORL C2+/O2+ ratios show remarkable agreement within each galactic system, while also being in agreement with the corresponding CEL ratios. For all five nebulae, the O2+/H+ abundance derived from multiple OII ORLs is found to be higher than the corresponding value derived from the strong [OIII] 4959, 5007A CELs, by factors of 1.8--2.7 for four of the nebulae. The LMC N11B nebula exhibits a more extreme discrepancy factor for the O2+ ion, ~5. Thus these HII regions exhibit ORL/CEL abundance discrepancy factors that are similar to those previously encountered amongst planetary nebulae. Our optical CEL O2+/H+ abundances agree to within 20-30 per cent with published O2+/H...

  1. An extreme, blueshifted iron line profile in the Narrow Line Seyfert 1 PG 1402+261; an edge-on accretion disk or highly ionized absorption?

    CERN Document Server

    Reeves, J N; Turner, T J

    2004-01-01

    We report on a short XMM-Newton observation of the radio-quiet Narrow Line Seyfert 1 PG 1402+261. The EPIC X-ray spectrum of PG 1402+261 shows a strong excess of counts between 6-9 keV in the rest frame. This feature can be modeled by an unusually strong (equivalent width 2 keV) and very broad (FWHM velocity of 110000 km/s) iron K-shell emission line. The line centroid energy at 7.3 keV appears blue-shifted with respect to the iron Kalpha emission band between 6.4-6.97 keV, while the blue-wing of the line extends to 9 keV in the quasar rest frame. The line profile can be fitted by reflection from the inner accretion disk, but an inclination angle of >60 deg is required to model the extreme blue-wing of the line. Furthermore the extreme strength of the line requires a geometry whereby the hard X-ray emission from PG 1402+261 above 2 keV is dominated by the pure-reflection component from the disk, while little or none of the direct hard power-law is observed. Alternatively the spectrum above 2 keV may instead b...

  2. Detection of the Intermediate-width Emission Line Region in Quasar OI 287 with the Broad Emission Line Region Obscured by the Dusty Torus

    CERN Document Server

    Li, Zhenzhen; Hao, Lei; Wang, Huiyuan; Ji, Tuo; Shi, Xiheng; Liu, Bo; Zhang, Shaohua; Liu, Wen-Juan; Pan, Xiang; Jiang, Peng

    2015-01-01

    The existence of intermediate-width emission line regions (IELRs) in active galactic nuclei has been discussed for over two decades. A consensus, however, is yet to be arrived at due to the lack of convincing evidence for their detection. We present a detailed analysis of the broadband spectrophotometry of the partially obscured quasar OI 287. The ultraviolet intermediate-width emission lines (IELs) are very prominent, in high contrast to the corresponding broad emission lines (BELs) which are heavily suppressed by dust reddening. Assuming that the IELR is virialized, we estimated its distance to the central black hole of $\\sim 2.9$ pc, similar to the dust sublimation radius of $\\sim 1.3$ pc. Photo-ionization calculations suggest that the IELR has a hydrogen density of $\\sim 10^{8.8}-10^{9.4} ~ \\rm cm^{-3}$, within the range of values quoted for the dusty torus near the sublimation radius. Both its inferred location and physical conditions suggest that the IELR originates from the inner surface of the dusty t...

  3. Measurements of Spatial Line Emission Profiles in the Main Scrape-Off Layer of the DIII-D Tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Groth, M; Ellis, R; Brooks, N; Fenstermacher, M; Lasnier, C; Meyer, W; Moller, J

    2009-06-05

    A video camera system is described that measures the spatial distribution of visible line emission emitted from the main scrape-off layer (SOL) of plasmas in the DIII-D tokamak. A wide-angle lens installed on an equatorial port and an in-vessel mirror which intercepts part of the lens view provide simultaneous tangential views of the SOL on the low-field and high-field sides of the plasma's equatorial plane. Tomographic reconstruction techniques are used to calculate the 2-D poloidal profiles from the raw data, and 1-D poloidal profiles simulating chordal views of other optical diagnostics from the 2-D profiles. The 2-D profiles can be compared with SOL plasma simulations; the 1-D profiles with measurements from spectroscopic diagnostics. Sample results are presented which elucidate carbon transport in plasmas with toroidally uniform injection of methane and argon transport in disruption mitigation experiments with massive gas jet injection.

  4. Authentication of newly established human esophageal squamous cell carcinoma cell line (YM-1) using short tandem repeat (STR) profiling method.

    Science.gov (United States)

    Ayyoob, Khosravi; Masoud, Khoshnia; Vahideh, Kazeminejad; Jahanbakhsh, Asadi

    2016-03-01

    Cross-contamination during or early after establishment of a new cell line could result in the worldwide spread of a misidentified cell line. Therefore, newly established cell lines need to be authenticated by a reference standard method. This study was conducted to investigate the authenticity of a newly established epithelial cell line of human esophageal squamous cell carcinoma (ESCC) called YM-1 using short tandem repeat (STR) DNA profiling method. Primary human ESCC epithelial cells were cultured from the fresh tumor tissue of an adult female patient. Growth characteristics and epithelial originality of YM-1 cells were studied. Genomic DNA was isolated from YM-1 cells harvested at passage 22 and ESCC donor tumor sample on two different days to prevent probable DNA contamination. STR profiling was performed using AmpFℓSTR® Identifiler® Plus PCR Amplification Kit. To address whether YM-1 cells undergo genetic alteration as the passage number increases, STR profiling was performed again on harvested cells at passage 51. YM-1 cells grew as a monolayer with a population doubling time of 40.66 h. Epithelial originality of YM-1 cells was confirmed using ICC/IF staining of cytokeratins AE1/AE3. The STR profile of the ESCC donor tumor sample was the same with YM-1 cells at passage 22. However, STR profile of the donor tumor sample showed an off-ladder (OL) allele in their D7S820 locus. Also, re-profiling of YM-1 cells at passage 51 showed a loss of heterozygosity (LOH) at D18S51 locus. This suggests that long-term culture of cell lines may alter their DNA profile. Comparison of the DNA fingerprinting results in DSMZ, and ATCC STR profiling databases confirmed unique identity of YM-1 cell line. This study provides an easy, fast, and reliable procedure for authentication of newly established cell lines, which helps in preventing the spread of misidentified cells and improving the reproducibility and validity of experiments, consequently.

  5. Millimetre spectral line mapping observations towards four massive star-forming H II regions

    Science.gov (United States)

    Li, Shanghuo; Wang, Junzhi; Zhang, Zhi-Yu; Fang, Min; Li, Juan; Zhang, Jiangshui; Fan, Junhui; Zhu, Qingfeng; Li, Fei

    2017-04-01

    We present spectral line mapping observations towards four massive star-forming regions - Cepheus A, DR21S, S76E and G34.26+0.15 - with the IRAM 30-m telescope at the 2 and 3 mm bands. In total, 396 spectral lines from 51 molecules, one helium recombination line, 10 hydrogen recombination lines and 16 unidentified lines were detected in these four sources. An emission line of nitrosyl cyanide (ONCN, 140, 14-130, 13) was detected in G34.26+0.15, as the first detection in massive star-forming regions. We found that c-C3H2 and NH2D show enhancement in shocked regions, as suggested by the evidence of SiO and/or SO emission. The column density and rotational temperature of CH3CN were estimated with the rotational diagram method for all four sources. Isotope abundance ratios of 12C/13C were derived using HC3N and its 13C isotopologue, which were around 40 in all four massive star-forming regions and slightly lower than the local interstellar value (∼65). The 14N/15N and 16O/18O abundance ratios in these sources were also derived using the double isotopic method, which were slightly lower than in the local interstellar medium. Except for Cep A, the 33S/34S ratios in the other three targets were derived, which were similar to that in the local interstellar medium. The column density ratios of N(DCN)/N(HCN) and N(DCO+)/N(HCO+) in these sources were more than two orders of magnitude higher than the elemental [D]/[H] ratio, which is 1.5 × 10-5. Our results show that the later stage sources, G34.26+0.15 in particular, present more molecular species than earlier stage sources. Evidence of shock activity is seen in all stages studied.

  6. Problems and countermeasures in construction of transmission line projects in permafrost regions

    Institute of Scientific and Technical Information of China (English)

    GuoShang Wang; QiHao Yu; YanHui You; Ze Zhang; Lei Guo; ShiJun Wang; Yong Yu

    2014-01-01

    Construction of power transmission lines is becoming an important part of permafrost engineering in China. This paper reviews the construction status and problems of transmission lines in different countries, as well as corresponding solutions that would be of practical significance for sustainable engineering practices. Russia has the longest history of transmission line construction in permafrost areas, with transmission lines (mainly 220 kV and 500 kV) spanning approximately 100,000 km. However, all countries suffer from permafrost-related tower foundation stability problems caused by freez-ing-thawing hazards such as frost heave and thaw settlement, frost lifting, and harmful cryogenic phenomena. As point-line transmission line constructions, the lines, poles and towers should be reasonably selected and installed with a comprehensive consideration of frozen soil characteristics to effectively reduce the occurrence of freezing-thawing dis-asters. Reinforced concrete pile foundations are widely used in the permafrost regions, and construction in winter is also a universal practice. Moreover, facilitating engineering measures like thermosyphons are an effective way to reduce freez-ing-thawing hazards and to maintain the stability of tower foundations.

  7. Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China.

    Science.gov (United States)

    Ye, Fang; Chen, Chuguang; Qin, Jian; Liu, Jie; Zheng, Congyi

    2015-10-01

    Cell lines are widely used as in vitro model systems in biologic and medical research. However, much of the research has been invalidated by the unwitting use of false cell lines. A significant proportion of the research involving human cell lines was initiated in China. Paradoxically, the cell lines used in China have never been authenticated. Here, we present a comprehensive survey of cross-contamination in 380 samples from 113 independent sources in China using short tandem repeat profiling methods. High levels of cross-contamination were uncovered (95 of 380, 25%). Notable false cell lines (e.g., KB and WISH) are still actively used under their false identity and tissue attributions. Most strikingly, 85.51% of lines established in China were misidentified (59 of 69) and accounted for over half of the misidentifications (59 of 95, 62.11%). Further, 93.22% of the contaminants in cell lines established in laboratories of China were HeLa cells or a possible hybrid of HeLa with an unknown cell line. Results from these misidentified lines have been published in thousands of potentially erroneous articles and may have distorted the findings visible to the scientific community. False lines have been used in drug screening, potentially leading to unusable or even harmful therapeutic strategies. We also noted the causes of contamination and provided suggestions for remediation.

  8. GRIS detection of Al-26 1809 keV line emission from the Galactic center region as a broad line

    Science.gov (United States)

    Naya, Juan E.; Barthelmy, Scott D.; Bartlett, Lyle M.; Gehrels, Neil; Leventhal, Marvin; Parsons, Ann; Teegarden, Bonnard J.; Tueller, Jack

    1997-01-01

    The gamma ray imaging spectrometer (GRIS) was used to observe the 1809 keV emission from the Galactic center region. The observed line is broader than the instrument resolution. The measured intrinsic width is 5.4 +/- 1.4 keV full width half medium, which is more than three times the maximum Doppler broadening expected due to Galactic rotation. The detection of such a wide feature, suggesting a high dispersion velocity has implications for the origin of Galactic Al-26. It suggests a supernova explosion origin or a Wolf-Rayet stellar wind origin of Al-26. The fact that the Al-26 has not come to rest after 10(exp 6) years presents a challenge to the current understanding of the Al-26 production and propagation in the Galaxy.

  9. De novo LINE-1 retrotransposition in HepG2 cells preferentially targets gene poor regions of chromosome 13.

    Science.gov (United States)

    Bojang, Pasano; Anderton, Mark J; Roberts, Ruth A; Ramos, Kenneth S

    2014-08-01

    Long interspersed nuclear elements (Line-1 or L1s) account for ~17% of the human genome. While the majority of human L1s are inactive, ~80-100 elements remain retrotransposition competent and mobilize through RNA intermediates to different locations within the genome. De novo insertions of L1s account for polymorphic variation of the human genome and disruption of target loci at their new location. In the present study, fluorescence in situ hybridization and DNA sequencing were used to characterize retrotransposition profiles of L1(RP) in cultured human HepG2 cells. While expression of synthetic L1(RP) was associated with full-length and truncated insertions throughout the entire genome, a strong preference for gene-poor regions, such as those found in chromosome 13 was observed for full-length insertions. These findings shed light into L1 targeting mechanisms within the human genome and question the putative randomness of L1 retrotransposition.

  10. A Revised Broad-Line Region Radius and Black Hole Mass for the Narrow-Line Seyfert 1 NGC 4051

    CERN Document Server

    Denney, K D; Peterson, B M; Pogge, R W; Atlee, D W; Bentz, M C; Bird, J C; Brokofsky, D J; Comins, M L; Dietrich, M; Doroshenko, V T; Eastman, J D; Efimov, Y S; Gaskell, C M; Hedrick, C H; Klimanov, S A; Klimek, E S; Kruse, A K; Lamb, J; Leighly, K; Minezaki, T; Nazarov, S V; Petersen, E A; Peterson, P; Poindexter, S; Sakata, Y; Schlesinger, K J; Sergeev, S G; Tobin, J J; Unterborn, C; Vestergaard, M; Watkins, A E; Yoshii, Y

    2009-01-01

    We present the first results from a high sampling rate, multi-month reverberation mapping campaign undertaken primarily at MDM Observatory with supporting observations from telescopes around the world. The primary goal of this campaign was to obtain either new or improved Hbeta reverberation lag measurements for several relatively low luminosity AGNs. We feature results for NGC 4051 here because, until now, this object has been a significant outlier from AGN scaling relationships, e.g., it was previously a ~2-3sigma outlier on the relationship between the broad-line region (BLR) radius and the optical continuum luminosity - the R_BLR-L relationship. Our new measurements of the lag time between variations in the continuum and Hbeta emission line made from spectroscopic monitoring of NGC 4051 lead to a measured BLR radius of R_BLR = 1.75 (+0.50 -0.68) light days and black hole mass of M_BH = 1.58 (+0.50 -0.65) x 10^6 M_sun. This radius is consistent with that expected from the R_BLR-L relationship, based on the...

  11. Radiation pressure force emission line profiles and black hole mass in active galactic nuclei

    CERN Document Server

    Netzer, H

    2010-01-01

    We present a new analysis of the motion of broad line region (BLR) clouds in active galactic nuclei (AGNs) taking into account the combined influence of gravity and radiation pressure force. We calculate cloud orbits under a large range of conditions and include the effect of a changing column density as a function of location. The dependence of radiation pressure force on the level of ionization and the column density are accurately computed. The main results are: a. The mean cloud location r(BLR) and the line widths (FWHMs) are combined in such a way that the simple virial mass estimate, r{BLR} FWHM^2/G, gives a reasonable approximation to the black hole mass M even when radiation pressure force is important. The reason is that L/M rather than L is the main parameter affecting the planar cloud motion. b. Reproducing the observed mean radius, FWHM and intensity of H-beta and CIV 1549 requires at least two different populations of clouds. c. The cloud location is a function of both L^{1/2} and L/M. Given this...

  12. Amplitude Analysis and Modeling of Regional Phases in PNE Profiles in Northern Eurasia and Seismic Regionalization

    Science.gov (United States)

    2006-06-30

    Morozova et al., 1999; Tryggvason et al., 2001). The West Siberian Basin (Figure 1-1) is the largest known basin structure in the world and covers over 3.4...mostly between 395 and 1212 m, and the source media include salt, sandstone/shale, clay, limestone/dolomite, granite, gabbro , tuff, apatite, anhydrite...shots in granite, 2 in tuff, 2 in chalk, 1 in gabbro , and 1 in anhydrite. Seven PNE profiles (RUBY-l, RUBY-2, QUARTZ, CIIATON, KIMBERLITE, RIFT, and

  13. Chromatic line-profile tomography to reveal exoplanetary atmospheres: application to HD 189733b

    CERN Document Server

    Borsa, Francesco; Poretti, Ennio

    2016-01-01

    Transmission spectroscopy can be used to constrain the properties of exoplanetary atmospheres. During a transit, the light blocked from the atmosphere of the planet leaves an imprint in the light coming from the star. This has been shown for many exoplanets with different techniques, with both photometry and spectroscopy. We aim at testing chromatic line-profile tomography as a new tool to investigate exoplanetary atmospheres. The signal imprinted on the cross-correlation function (CCF) by a planet transiting its star is dependent on the planet-to-star radius ratio. We want to verify if the precision reachable on the CCF obtained from a subset of the spectral orders of the HARPS spectrograph is enough to discriminate the radius of a planet at different wavelengths. Methods. We analyze HARPS archival data of three transits of HD 189733b. We divide the HARPS spectral range in 7 broadbands, calculating for each band the ratio between the area of the out-of-transit CCF and the area of the signal imprinted by the ...

  14. PROJECT VeSElkA: ANALYSIS OF BALMER LINE PROFILES OF SLOWLY ROTATING CHEMICALLY PECULIAR STARS

    Energy Technology Data Exchange (ETDEWEB)

    Khalack, V.; LeBlanc, F., E-mail: khalack.viktor@umoncton.ca [Département de Physique et d’Astronomie, Université de Moncton, Moncton, N.-B., E1A 3E9 (Canada)

    2015-07-15

    We present results for the estimation of gravity, effective temperature, and radial velocity of poorly studied chemically peculiar stars recently observed with the spectropolarimeter Echelle SpectroPolarimetric Device for Observations of Stars at the Canada–France–Hawaii Telescope in the frame of the Vertical Stratification of Element Abundances project. The effective temperature and surface gravity values are determined for the very first time for four of the stars from our sample (HD 23878, HD 83373, HD 95608, and HD 164584). Grids of stellar atmosphere models with the corresponding fluxes have been calculated using version 15 of the PHOENIX code for effective temperatures in the range of 5000–15,000 K, for the logarithm of surface gravities in the range of 3.0–4.5 and for the metallicities from −1.0 to +1.5. We used these fluxes to fit the Balmer line profiles employing the code FITSB2 that produces estimates of the effective temperature, gravity, and radial velocity for each star. When possible, our results are compared to those previously published. The physical characteristics of 16 program stars are discussed with the future aim to study the abundance anomalies of chemical species and the possible vertical abundance stratification in their stellar atmosphere.

  15. Project VeSElkA: Analysis of Balmer line profiles in slowly rotating chemically peculiar stars

    CERN Document Server

    Khalack, Viktor

    2015-01-01

    We present results for the estimation of gravity, effective temperature, and radial velocity of poorly studied chemically peculiar stars recently observed with the spectropolarimeter Echelle SpectroPolarimetric Device for Observations of Stars at the Canada-France-Hawaii Telescope in the frame of the Vertical Stratification of Element Abundances project. The effective temperature and surface gravity values are determined for the very first time for four of the stars from our sample (HD23878, HD83373, HD95608, and HD164584). Grids of stellar atmosphere models with the corresponding fluxes have been calculated using version 15 of the PHOENIX code for effective temperatures in the range of 5000-15,000 K, for the logarithm of surface gravities in the range of 3.0-4.5 and for the metallicities from -1.0 to +1.5. We used these fluxes to fit the Balmer line profiles employing the code FITSB2 that produces estimates of the effective temperature, gravity, and radial velocity for each star. When possible, our results a...

  16. MODELING THE Fe K LINE PROFILES IN TYPE I ACTIVE GALACTIC NUCLEI WITH A COMPTON-THICK DISK WIND

    Energy Technology Data Exchange (ETDEWEB)

    Tatum, M. M.; Turner, T. J. [Department of Physics, University of Maryland, Baltimore County, Baltimore, MD 21250 (United States); Sim, S. A. [Research School of Astronomy and Astrophysics, Mount Stromlo Observatory, Cotter Road, Weston Creek, ACT 2611 (Australia); Miller, L. [Department of Physics, University of Oxford, Denys Wilkinson Building, Keble Road, Oxford OX1 3RH (United Kingdom); Reeves, J. N.; Patrick, A. R. [Astrophysics Group, School of Physical and Geographical Sciences, Keele University, Keele, Staffordshire ST5 5BG (United Kingdom); Long, K. S. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States)

    2012-06-20

    We have modeled a small sample of Seyfert galaxies that were previously identified as having simple X-ray spectra with little intrinsic absorption. The sources in this sample all contain moderately broad components of Fe K-shell emission and are ideal candidates for testing the applicability of a Compton-thick accretion disk wind model to active galactic nucleus (AGN) emission components. Viewing angles through the wind allow the observer to see the absorption signature of the gas, whereas face-on viewing angles allow the observer to see the scattered light from the wind. We find that the Fe K emission line profiles are well described with a model of a Compton-thick accretion disk wind of solar abundances, arising tens to hundreds of gravitational radii from the central black hole. Further, the fits require a neutral component of Fe K{alpha} emission that is too narrow to arise from the inner part of the wind, and likely comes from a more distant reprocessing region. Our study demonstrates that a Compton-thick wind can have a profound effect on the observed X-ray spectrum of an AGN, even when the system is not viewed through the flow.

  17. Application of a Continued-Fraction-Based Theory to Line-Profile in Mn-Doped GaN Film

    Science.gov (United States)

    Park, Jung-Il; Lee, Hyeong-Rag; Lee, Su-Ho

    2012-05-01

    Starting with the Kubo formalism and using the projection operator technique (POT) introduced by Kawabata, the optical quantum transition line-profiles (QTLPs) formula for a Mn-doped wurtzite GaN film was derived as a function of temperature at a frequency of 9.49 GHz (X-band), on the basis of continued fraction representation (CFR) which is a counterpart of the conventional series expansion (CSE). Utilizing this formula we obtained the fine-structure parameter a - F = 9.4 ×10-4 cm-1 and fitting parameter ζ= 4.1. The optical quantum transition half-widths (QTHWs) obtained with the use of these parameters agrees quite well with the existing experimental result in the temperature region T > 20 K. The QTHWs increase with increasing temperature due to the interaction of electrons with optical phonons. Thus, the present technique is considered to be more convenient to explain the resonant system as in the case of other optical transition problems.

  18. Expression profiling of colon cancer cell lines and colon biopsies: Towards a screening system for potential cancer-preventive compounds

    NARCIS (Netherlands)

    Erk, van M.J.; Krul, C.A.M.; Caldenhoven, E.; Stierum, R.H.; Peters, W.H.; Woutersen, R.A.; Ommen, van B.

    2005-01-01

    Interest in mechanisms of colon cancer prevention by food compounds is strong and research in this area is often performed with cultured colon cancer cells. In order to assess utility for screening of potential cancer-preventive (food) compounds, expression profiles of 14 human cell lines derived

  19. Expression profiling of colon cancer cell lines and colon biopsies: towards a screening system for potential cancer-preventive compounds.

    NARCIS (Netherlands)

    Erk, M.J. van; Krul, C.A.; Caldenhoven, E.; Stierum, R.H.; Peters, W.H.M.; Woutersen, R.A.; Ommen, B.

    2005-01-01

    Interest in mechanisms of colon cancer prevention by food compounds is strong and research in this area is often performed with cultured colon cancer cells. In order to assess utility for screening of potential cancer-preventive (food) compounds, expression profiles of 14 human cell lines derived

  20. Transcriptomic profile of two canine mammary cancer cell lines with different proliferative and anti-apoptotic potential

    NARCIS (Netherlands)

    Krol, M.; Skierski, J.; Rao, N.A.; Hellmen, E.; Mol, J.A.; Motyl, T.

    2009-01-01

    J Physiol Pharmacol. 2009 May;60 Suppl 1:95-106. Transcriptomic profile of two canine mammary cancer cell lines with different proliferative and anti-apoptotic potential. Krol M, Pawlowski KM, Skierski J, Rao NA, Hellmen E, Mol JA, Motyl T. Department of Physiological Sciences, Faculty of Veterinary

  1. Expression profiling of colon cancer cell lines and colon biopsies: Towards a screening system for potential cancer-preventive compounds

    NARCIS (Netherlands)

    Erk, van M.J.; Krul, C.A.M.; Caldenhoven, E.; Stierum, R.H.; Peters, W.H.; Woutersen, R.A.; Ommen, van B.

    2005-01-01

    Interest in mechanisms of colon cancer prevention by food compounds is strong and research in this area is often performed with cultured colon cancer cells. In order to assess utility for screening of potential cancer-preventive (food) compounds, expression profiles of 14 human cell lines derived fr

  2. Expression profiling of colon cancer cell lines and colon biopsies: towards a screening system for potential cancer-preventive compounds.

    NARCIS (Netherlands)

    Erk, M.J. van; Krul, C.A.; Caldenhoven, E.; Stierum, R.H.; Peters, W.H.M.; Woutersen, R.A.; Ommen, B.

    2005-01-01

    Interest in mechanisms of colon cancer prevention by food compounds is strong and research in this area is often performed with cultured colon cancer cells. In order to assess utility for screening of potential cancer-preventive (food) compounds, expression profiles of 14 human cell lines derived fr

  3. The Lick AGN Monitoring Project: Alternate Routes to a Broad-line Region Radius

    CERN Document Server

    Greene, Jenny E; Barth, Aaron J; Bennert, Vardha N; Bentz, Misty C; Filippenko, Alexei V; Gates, Elinor; Malkan, Matthew A; Treu, Tommaso; Walsh, Jonelle L; Woo, Jong-Hak

    2010-01-01

    It is now possible to estimate black hole masses across cosmic time, using broad emission lines in active galaxies. This technique informs our views of how galaxies and their central black holes coevolve. Unfortunately, there are many outstanding uncertainties associated with these "virial" mass estimates. One of these comes from using the accretion luminosity to infer a size for the broad-line region. Incorporating the new sample of low-luminosity active galaxies from our recent monitoring campaign at Lick Observatory, we recalibrate the radius-luminosity relation with tracers of the accretion luminosity other than the optical continuum. We find that the radius of the broad-line region scales as the square root of the X-ray and Hbeta luminosities, in agreement with recent optical studies. On the other hand, the scaling appears to be marginally steeper with narrow-line luminosities. This is consistent with a previously observed decrease in the ratio of narrow-line to X-ray luminosity with increasing total lum...

  4. A far-infrared molecular and atomic line survey of the Orion KL region

    CERN Document Server

    Lerate, M R; Swinyard, B M; Goicoechea, J R; Cernicharo, J; Grundy, T W; Lim, T L; Polehampton, E T; Baluteau, J P; Viti, S; Yates, J

    2006-01-01

    We have carried out a high spectral resolution line survey towards the Orion Kleinmann-Low (KL) cluster from 44-188 um. The observations were taken with the Long Wavelength Spectrometer (LWS) in Fabry-Perot mode, on board the Infrared Space Observatory (ISO). A total of 152 lines are clearly detected and a further 34 features are present as possible detections. The spectrum is dominated by the molecular species H2O, OH and CO, along with [OI] and [CII] lines from PDR or shocked gas and [OIII], [NIII] lines from the foreground M42 HII region. Several isotopic species, as well as NH3, are also detected. HDO and H3O+ are tentatively detected for the first time in the far-infrared range towards Orion-KL. A basic analysis of the line observations is carried out, by comparing with previous measurements and published models and deriving rotational temperatures and column densities in the case of the molecular species. The complexity of the region requires more sophisticated models for the interpretation of all the l...

  5. Discoveries of Diffuse Iron Line Sources from the Sgr B Region

    CERN Document Server

    Koyama, K; Hyodo, Y; Matsumoto, H; Tsuru, T G; Maeda, Y; Murakami, H; Yamauchi, S; Kissel, S E; Soong, C Y; Koyama, Katsuji; Inui, Tatsuya; Hyodo, Yoshiaki; Matsumoto, Hironori; Tsuru, Takeshi Go; Maeda, Yoshitomo; Murakami, Hiroshi; Yamauchi, Shigeo; Kissel, Steven E.; Soong, Chan Yang

    2006-01-01

    The radio complex Sgr B region is observed with the X-Ray Imaging Spectrometers (XIS) on board Suzaku. This region exhibits diffuse iron lines at 6.4, 6.7 and 6.9 keV, which are K$\\alpha$ lines of Fe \\emissiontype{I} (neutral iron), Fe\\emissiontype{XXV} (He-like iron) and Fe\\emissiontype{XXVI} (H-like iron), respectively. The high energy resolving power of the XIS provides the separate maps of the K-shell transition lines from Fe\\emissiontype{I} (6.4 keV) and Fe\\emissiontype{XXV} (6.7 keV). Although the 6.7 keV line is smoothly distributed over the Sgr B region, a local excess is found near at $(l, b) = (\\timeform {0D.61}, \\timeform{0D.01})$, possibly a new SNR. The plasma temperature is \\textit{kT} $\\sim$3 keV and the age is estimated to be around several$\\times10^{3}$ years. The 6.4 keV image is clumpy with local excesses nearby Sgr B2 and at $(l, b) = (\\timeform{0D.74}, -\\timeform{0D.09})$. Like Sgr B2, this excess may be another candidate of an X-ray reflection nebula (XRN).

  6. Theoretical Emission-Line Profiles of Active Galactic Nuclei and the Unified Model. I. The Face-on Torus

    Science.gov (United States)

    Quintilio, R.; Viegas, S. M.

    1997-01-01

    Theoretical emission-line profiles are obtained for active galactic nuclei (AGNs) taking into account the presence of an obscuring torus around the central energy source. For the sake of simplicity, the torus is represented by a cylindrical shell characterized by the inner and outer radius and the opening angle. In this paper we discuss the results with angle of sight equal to 0, i.e., for a face-on torus. Different line profiles are obtained following the torus parameters. The line profiles may show more than one peak and bumps, depending on the torus dimensions. The main parameter determining the number of peaks or bumps is the opening angle. Thus, the observed line shape may be a good indicator of the torus characteristics. As an example, the fit to the observed [O III] λ5007 emission line of NGC 4151 is presented. The model reproduces the FWHM and the asymmetrical bumps observed. Partially supported by the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) under Grant 92/4335-9.

  7. Identification of differential gene expression profiles of radioresistant lung cancer cell line established by fractionated ionizing radiation in vitro

    Institute of Scientific and Technical Information of China (English)

    XU Qing-yong; GAO Yuan; LIU Yan; YANG Wei-zhi; XU Xiang-ying

    2008-01-01

    Background Radiotherapy plays a critical role in the management of non-small cell lung cancer (NSCLC). This study was conducted to identify gene expression profiles of acquired radioresistant NSCLC cell line established by fractionated ionizing radiation (FIR) by cDNA microarray.Methods The human lung adenocarcinoma cell line Anip973 was treated with high energy X-ray to receive 60 Gy in 4 Gy fractions. The radiosensitivity of Anip973R and its parental line were measured by clonogenic assay. Gene expression profiles of Anip973R and its parental line were analyzed using cDNA microarray consisting of 21 522 human genes.Identified partly different expressive genes were validated by quantitative reverse transcription-polymerase chain reaction (Q-RT-PCR).Results Fifty-nine upregulated and 43 downregulated genes were identified to radio-resistant Anip973R. Up-regulated genes were associated with DNA damage repair (DDB2), extracellular matrix (LOX), cell adhesion (CDH2), and apoptosis (CRYAB). Down-regulated genes were associated with angiogenesis (GBP-1), immune response (CD83), and calcium signaling pathway (TNNC1). Subsequent validation of selected eleven genes (CD24, DDB2, IGFBP3, LOX,CDH2, CRYAB, PROCR, ANXA1 DCN, GBP-1 and CD83) by Q-RT-PCR was consistent with microarray analysis.Conclusions Fractionated ionizing radiation can lead to the development of radiation resistance. Altered gene profiles of radioresistant cell line may provide new insights into mechanisms underlying clinical radioresistance for NSCLC.

  8. Sizes and Kinematics of Extended Narrow-line Regions in Luminous Obscured AGN Selected by Broadband Images

    Science.gov (United States)

    Sun, Ai-Lei; Greene, Jenny E.; Zakamska, Nadia L.

    2017-02-01

    To study the impact of active galactic nuclei (AGN) feedback on their galactic ISM, we present Magellan long-slit spectroscopy of 12 luminous nearby obscured AGN ({L}{bol}∼ {10}45.0-46.5 {erg} {{{s}}}-1, z ∼ 0.1). These objects are selected from a parent sample of spectroscopically identified AGN to have high [O iii]λ5007 and Wide-field Infrared Survey Explorer mid-IR luminosities and extended emission in the Sloan Digital Sky Survey r-band images, suggesting the presence of extended [O iii]λ5007 emission. We find spatially resolved [O iii] emission (2–35 kpc) in 8 out of 12 of these objects. Combined with samples of higher luminosity obscured AGN, we confirm that the size of the narrow-line region (RNLR) scales with the mid-IR luminosity until the relation flattens at RNLR ∼ 10 kpc. Nine out of 12 objects in our sample have regions with broad [O iii] line widths (w80 > 600 km s‑1), indicating outflows. We define these regions as the kinematically disturbed region (KDR). The size of the KDR ({R}{KDR}) is typically smaller than RNLR by few kiloparsecs but also correlates strongly with the AGN mid-IR luminosity. Given the uncertain outflow mass, we derive a loose constraint on the outflow energy efficiency {η }{med}=\\dot{E}/{L}{bol}∼ 0.007 % {--}7 % . We find no evidence for an AGN luminosity threshold below which outflows are not launched. To explain the sizes, velocity profiles, and high occurrence rates of the outflows in the most luminous AGN, we propose a scenario in which energy-conserving outflows are driven by AGN episodes with ∼108 year durations. Within each episode, the AGN is unlikely to be constantly luminous but could flicker on shorter timescales (≲107 yr) with a moderate duty cycle (∼10%).

  9. Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets

    DEFF Research Database (Denmark)

    Bergholdt, R.; Karlsen, A.E.; Hagedorn, Peter;

    2007-01-01

    We recently finemapped a type 1 diabetes (T1D)-linked region on chromosome 21, indicating that one or more T1D-linked genes exist in this region with 33 annotated genes. In the current study, we have taken a novel approach using transcriptional profiling in predicting and prioritizing the most...... likely candidate genes influencing beta-cell function in this region. Two array-based approaches were used, a rat insulinoma cell line (INS-1alphabeta) overexpressing pancreatic duodenum homeobox 1 (pdx-1) and treated with interleukin 1beta (IL-1beta) as well as human pancreatic islets stimulated...... with a mixture of cytokines. Several candidate genes with likely functional significance in T1D were identified. Genes showing differential expression in the two approaches were highly similar, supporting the role of these specific gene products in cytokine-induced beta-cell damage. These were genes involved...

  10. Predicting disordered regions in proteins using the profiles of amino acid indices

    Science.gov (United States)

    Han, Pengfei; Zhang, Xiuzhen; Feng, Zhi-Ping

    2009-01-01

    Background Intrinsically unstructured or disordered proteins are common and functionally important. Prediction of disordered regions in proteins can provide useful information for understanding protein function and for high-throughput determination of protein structures. Results In this paper, algorithms are presented to predict long and short disordered regions in proteins, namely the long disordered region prediction algorithm DRaai-L and the short disordered region prediction algorithm DRaai-S. These algorithms are developed based on the Random Forest machine learning model and the profiles of amino acid indices representing various physiochemical and biochemical properties of the 20 amino acids. Conclusion Experiments on DisProt3.6 and CASP7 demonstrate that some sets of the amino acid indices have strong association with the ordered and disordered status of residues. Our algorithms based on the profiles of these amino acid indices as input features to predict disordered regions in proteins outperform that based on amino acid composition and reduced amino acid composition, and also outperform many existing algorithms. Our studies suggest that the profiles of amino acid indices combined with the Random Forest learning model is an important complementary method for pinpointing disordered regions in proteins. PMID:19208144

  11. Health-Related Physical Fitness in Hungarian Youth: Age, Sex, and Regional Profiles

    Science.gov (United States)

    Welk, Gregory J.; Saint-Maurice, Pedro F.; Csányi, Tamás

    2015-01-01

    Purpose: The purpose of this study was to examine region, age, and sex profiles of physical fitness in Hungarian youth. Method: A sample of 2,602 Hungarian youth aged 10 to 18 years old completed a series of physical fitness field tests: the Progressive Aerobic Cardiorespiratory Endurance Run (PACER) fitness test, body mass index (BMI), percent…

  12. Cognitive profiles and regional cerebral blood flow patterns in dementia of the Alzheimer type

    DEFF Research Database (Denmark)

    Waldemar, G; Bruhn, P; Schmidt, E

    1994-01-01

    Individual cognitive profiles and correlations between cognitive functions and regional cerebral blood flow (rCBF) were analyzed in 20 consecutive patients with a clinical diagnosis of probable Alzheimer's disease (AD). CBF was measured with high resolution single photon emission computed...

  13. Health-Related Physical Fitness in Hungarian Youth: Age, Sex, and Regional Profiles

    Science.gov (United States)

    Welk, Gregory J.; Saint-Maurice, Pedro F.; Csányi, Tamás

    2015-01-01

    Purpose: The purpose of this study was to examine region, age, and sex profiles of physical fitness in Hungarian youth. Method: A sample of 2,602 Hungarian youth aged 10 to 18 years old completed a series of physical fitness field tests: the Progressive Aerobic Cardiorespiratory Endurance Run (PACER) fitness test, body mass index (BMI), percent…

  14. X-ray Spectroscopy of the Radiation-Driven Winds of Massive Stars: Line Profile and Line Ratio Diagnostics

    CERN Document Server

    Cohen, David H

    2009-01-01

    Massive stars drive powerful, supersonic winds via the radiative momentum associated with the thermal UV emission from their photospheres. Shock phenomena are ubiquitous in these winds, heating them to millions, and sometimes tens of millions, of degrees. The emission line spectra from the shock-heated plasma provide powerful diagnostics of the winds' physical conditions, which in turn provide constraints on models of wind shock heating. Here I show how x-ray line transfer is affected by photoelectric absorption in the partially ionized component of the wind and how it can be modeled to determine the astrophysically important mass-loss rates of these stellar winds. I also discuss how photoexcitation out of metastable excited levels of helium-like ions can provide critical information about the location of the hot plasma in magnetically channeled massive star winds.

  15. Spatial structure in lines in the 3398-3526 A region at the extreme limb - Observation, identification and interpretation

    Science.gov (United States)

    Canfield, R. C.; Pasachoff, J. M.; Stencel, R. E.; Beckers, J. M.

    1978-01-01

    Spectrograms of high spatial and spectral resolution have been obtained of the extreme solar limb, using the vacuum tower telescope of Sacramento Peak Observatory. Emission lines in the range 3398-3526 A have been identified and classified according to intensity, spatial structure (intensity variation), and profile. Some lines show spatial intensity variation; others do not. It is shown that this effect is related to the abundance of the element responsible for the line and the mean lower-level excitation potential of interlocked lines. This effect is explained in terms of radiative interlocking with other lines, as well as the characteristic size of the volume contributing to the mean intensity.

  16. Modelling of the electron density height profiles in the mid-latitude ionospheric D-region

    Directory of Open Access Journals (Sweden)

    P. Y. Mukhtarov

    1996-06-01

    Full Text Available A new mid-latitude D-region (50-105 km model of the electron density is presented obtained on the basis of a full wave theory and by a trial-and-error inversion method. Daytime (at different solar zenith angles absorption measurements by A3-technique made in Bulgaria yielded data with the aid of which the seasonal and diurnal courses of the Ne(h-profiles were derived. Special attention is drawn to the event diurnal asymmetry, or uneven formation of the ionosphere as a function of insulation. The latter is probably connected with the influence of the diurnal fluctuations in the local temperature on the chemistry involved in the electron loss rate, as well as the diurnal variations of the main ionizing agent (NO in the D-region. That is why the Ne(h-profiles in the midlatitude D-region are modelled separately for morning and afternoon hours.

  17. The Fading of the Narrow-Line Region in 3C 390.3: Erratum

    Science.gov (United States)

    Clavel, J.; Wamsteker, W.

    1988-07-01

    The Letter "The Fading of the Narrow-Line Region in 3C 390.3" by J. Clavel and W. Wamsteker (Ap. J. [Letters], 320, L9 [1987]) contains an error in the last two sentences of section IIIb: The density we compute for the broad line region (BLR) gas is wrong by a factor of 10 exactly and should read 10^11^ cm^-3^ instead of 10^10^. Such a density is about 30 times larger than the canonical 10^9.5^ cm^-3^ value generally used in model calculations but similar to the density inferred for the BLR in NGC 4151 by J. Clavel et al. (Ap. J., 321, 251 [1987]). The authors are grateful to Paolo Padovani from STScI for bringing this error to their attention.

  18. Hepatic drug metabolizing profile of Flinders Sensitive Line rat model of depression.

    Science.gov (United States)

    Kotsovolou, Olga; Ingelman-Sundberg, Magnus; Lang, Matti A; Marselos, Marios; Overstreet, David H; Papadopoulou-Daifoti, Zoi; Johanson, Inger; Fotopoulos, Andrew; Konstandi, Maria

    2010-08-16

    The Flinders Sensitive Line (FSL) rat model of depression exhibits some behavioral, neurochemical, and pharmacological features that have been reported in depressed patients and has been very effective in screening antidepressants. Major factor that determines the effectiveness and toxicity of a drug is the drug metabolizing capacity of the liver. Therefore, in order to discriminate possible differentiation in the hepatic drug metabolism between FSL rats and Sprague-Dawley (SD) controls, their hepatic metabolic profile was investigated in this study. The data showed decreased glutathione (GSH) content and glutathione S-transferase (GST) activity and lower expression of certain major CYP enzymes, including the CYP2B1, CYP2C11 and CYP2D1 in FSL rats compared to SD controls. In contrast, p-nitrophenol hydroxylase (PNP), 7-ethoxyresorufin-O-dealkylase (EROD) and 16alpha-testosterone hydroxylase activities were higher in FSL rats. Interestingly, the wide spread environmental pollutant benzo(alpha)pyrene (B(alpha)P) induced CYP1A1, CYP1A2, CYP2B1/2 and ALDH3c at a lesser extend in FSL than in SD rats, whereas the antidepressant mirtazapine (MIRT) up-regulated CYP1A1/2, CYP2C11, CYP2D1, CYP2E1 and CYP3A1/2, mainly, in FSL rats. The drug also further increased ALDH3c whereas suppressed GSH content in B(alpha)P-exposed FSL rats. In conclusion, several key enzymes of the hepatic biotransformation machinery are differentially expressed in FSL than in SD rats, a condition that may influence the outcome of drug therapy. The MIRT-induced up-regulation of several drug-metabolizing enzymes indicates the critical role of antidepressant treatment that should be always taken into account in the designing of treatment and interpretation of insufficient pharmacotherapy or drug toxicity.

  19. Constraints on the Broad Line Region Properties and Extinction in Local Seyferts

    CERN Document Server

    Schnorr-Müller, Allan; Korista, K T; Burtscher, L; Rosario, D; Storchi-Bergmann, T; Contursi, A; Genzel, R; Graciá-Carpio, J; Hicks, E K S; Janssen, A; Koss, M; Lin, M -Y; Lutz, D; Maciejewski, W; Müller-Sánchez, F; de Xivry, G Orban; Riffel, R; Riffel, R A; Schartmann, M; Sternberg, A; Sturm, E; Tacconi, L; Veilleux, S; Ulrich, O A

    2016-01-01

    We use high spectral resolution (R > 8000) data covering 3800-13000\\r{A} to study the physical conditions of the broad line region (BLR) of nine nearby Seyfert 1 galaxies. Up to six broad HI lines are present in each spectrum. A comparison - for the first time using simultaneous optical to near-infrared observations - to photoionisation calculations with our devised simple scheme yields the extinction to the BLR at the same time as determining the density and photon flux, and hence distance from the nucleus, of the emitting gas. This points to a typical density for the HI emitting gas of 10$^{11}$cm$^{-3}$ and shows that a significant amount of this gas lies at regions near the dust sublimation radius, consistent with theoretical predictions. We also confirm that in many objects the line ratios are far from case B, the best-fit intrinsic broad-line H$\\alpha$/H$\\beta$ ratios being in the range 2.5-6.6 as derived with our photoionization modeling scheme. The extinction to the BLR, based on independent estimates...

  20. The HST view of the broad line region in low luminosity AGN

    CERN Document Server

    Balmaverde, B; di Torino, INAF - Osservatorio Astrofisico

    2014-01-01

    We analyze the properties of the broad line region (BLR) in low luminosity AGN by using HST/STIS spectra. We consider a sample of 24 nearby galaxies in which the presence of a BLR has been reported from their Palomar ground-based spectra. Following a widely used strategy, we used the [SII] doublet to subtract the contribution of the narrow emission lines to the H-alpha+[NII] complex and to isolate the BLR emission. Significant residuals that suggest a BLR, are present. However, the results change substantially when the [OI] doublet is used. Furthermore, the spectra are also reproduced well by just including a wing in the narrow H-alpha and [NII] lines, thus not requiring the presence of a BLR. We conclude that complex structure of the narrow line region (NLR) is not captured with this approach and that it does not lead to general robust constraints on the properties of the BLR in these low luminosity AGN. Nonetheless, the existence of a BLR is firmly established in 5 Seyferts, and 5 LINERs. However, the measu...

  1. The Size of Narrow Line Region and [OIII] Luminosity Analyzed from SDSS DR7 Quasar Catalogue

    Indian Academy of Sciences (India)

    Zhi-Fu Chen; Y.-P. Qin; Z.-Y. Chen; L.-Z. Lü

    2011-03-01

    In this work, we constructed a sample of 4002 quasars from SDSS DR7 quasar catalogue to calculate the electron density and size of narrow line region. We find that the electron densities are ∼ 103/cm3, and the sizes are between 27 and 775 pc. We also find that, in the ionization cone, the sizes are tightly correlated with the luminosities of [OIII]5007.

  2. Region-specific versus country-specific poverty lines in analysis of poverty

    OpenAIRE

    Mogstad, Magne; Langørgen, Audun; Aaberge, Rolf

    2007-01-01

    Abstract: The standard practice in most OECD countries is to measure and evaluate poverty on the basis of a poverty line defined as a specific proportion of the median equivalent income within a country. However, this approach disregards regional differences in prices and needs within a country and may, therefore, provide an incomplete and even an incorrect picture of the extent as well as the geographical and demographical composition of the poor. To account for differences in...

  3. A Near-Infrared Imaging Study of Seyfert Galaxies with Extended Emission line Regions

    Science.gov (United States)

    Alonso-Herrero, Almudena; Simpson, Chris; Ward, Martin J.; Wilson, Andrew S.

    1997-01-01

    We present a near-infrared J,H,K and L' band (1.25 - 3.80 mue) imaging study of a sample of Seyfert galaxies, including some of the best studied examples of these with extended emission line regions (EELR). The observed near-IR nuclear colors are consistent with mixture of emmisions from an old stellar population and unredening hot dust.

  4. Observations of Ha Line Profiles in Be Stars Using 45 cm Cassegrain Telescope at Arthur C Clarke Institute

    Science.gov (United States)

    Gunasekera, S.; Adassuriya, J.; Medagangoda, N. I.

    2008-12-01

    H-alpha line profiles of 13 Be starts (mv d6.9) were observed using 45 cm Cassegrain telescope at the Arthur C Clarke Institute, Sri Lanka during the period of August 2005 to March 2006. High resolution spectra of these Be stars were obtained using 1200 lines/mm reflective grating in first order with resolution R=λ/Δλ=76800 and linear spectral dispersion 0.31 Å per pixel at 6563 Å in order to find out line parameters such as equivalent width, full width at half-maxima, V/R ratios etc. A study of the correlations between different pairs of parameters was obtained and compared with previous analysis to see the behavior of circumstellar disk. We found a good correlation (0.8) between FWHM and v sin i and strong correlation (0.96) between the Ip/Ic and the equivalent width. The drastic changes of the V/R ratio in profiles HR5941 and HR6712 imply the circumstellar disk is more likely an elliptical shape and undergoes slow apsidal motion. The inclination angles (i) were estimated for each star using the theoretical vsin i values and assuming star rotates in 0.8Vc and are matched with the structure of the line profiles.

  5. Using Profiles Based on Nucleotide Hydrophobicity to Define Essential Regions for Splicing

    Directory of Open Access Journals (Sweden)

    Galina Boldina, Anatoly Ivashchenko, Mireille Régnier

    2009-01-01

    Full Text Available The splice-site sequences of U2-type introns are highly degenerate, so many different sequences can function as U2-type splice sites. Using our new profiles based on hydrophobicity properties we pointed out specific properties for regions surrounding splice sites. We built a set T of flanking regions of genes with 1-3 introns from 21st and 22nd chromosomes extracted from GenBank to define positions having conserved properties, namely hydrophobicity, that are potentially essential for recognition by spliceosome. GT–AG introns exist in U2 and U12-types. Therefore, intron type cannot be simply determined by the dinucleotide termini. We attempted to distinguish U2 and U12-types introns with help of hydrophobicity profiles on sets of spice sites for U2 or U12-type introns extracted from SpliceRack database. The positions given by our method, which may be important for recognition by spliceosome, were compared to the nucleotide consensus provided by a classical method, Pictogram. We showed that there is a similarity of hydrophobicity profiles inside intron types. On one hand, GT–AG and GC–AG introns belonging to U2-type have resembling hydrophobicity profiles as well as AT–AC and GT–AG introns belonging to U12-type. On the other hand, hydrophobicity profiles of U2 and U12-types GT–AG introns are completely different. We suggest that hydrophobicity profiles facilitate definition of intron type, distinguishing U2 and U12 intron types and can be used to build programs to search splice site and to evaluate their strength. Therefore, our study proves that hydrophobicity profiles are informative method providing insights into mechanisms of splice sites recognition.

  6. Magnetic Neutral Line-Associated Radio Sources and Evolution of the Active Region NOAA 7321

    Science.gov (United States)

    Uralov, A. M.; Nakajima, H.; Zandanov, V. G.; Grechnev, V. V.

    1999-12-01

    We report evolution of the active region NOAA~7321 in which radio sources associated with magnetic neutral lines (so-called Neutral Line Associated Source, NLS) were studied on the basis of data of Nobeyama Radioheliograph. We provide physical interpretation of the NLS in terms of topological magnetic reconnection model and discuss their relation to evolution of the active region. Two kinds of the NLS were observed at 17~GHz, i.e. rising and stationary sources. Their presence was associated with substantial expansion of the active region's magnetosphere and accompanied by gradual evolution of spine-like structures visible in soft X-rays before long-duration flares. We suggest that the rising 17~GHz source corresponded to a ``horizontal'' current sheet moving upward which was not bright in soft X-rays. Bright X-ray spine was a boundary of that current sheet. Formation of X-points are believed to be responsible for the presence of low-lying stationary sources arranged along the photospheric neutral line.

  7. Reverberation Mapping of the Broad-line Region in NGC 5548: Evidence for Radiation Pressure?

    CERN Document Server

    Lu, Kai-Xing; Hu, Chen; Li, Yan-Rong; Zhang, Zhi-Xiang; Wang, Kai; Huang, Ying-Ke; Bi, Shao-Lan; Bai, Jin-Ming; Ho, Luis C; Wang, Jian-Min

    2016-01-01

    NGC 5548 is the best-observed reverberation-mapped active galactic nucleus with long-term, intensive monitoring. Here we report results from a new observational campaign between January and July, 2015. We measure the centroid time lag of the broad H$\\beta$ emission line with respect to the 5100 \\AA continuum and obtain $\\tau_{\\rm cent} = 7.20^{+1.33}_{-0.35}$ days in the rest frame. This yields a black hole mass of $M_{\\bullet}=8.71^{+3.21}_{-2.61} $x$ 10^{7}M_{\\odot}$ using a broad H$\\beta$ line dispersion of $3124\\pm302$ km s$^{-1}$ and a virial factor of $f_{_{\\rm BLR}}=6.3\\pm1.5$ for the broad-line region (BLR), consistent with the mass measurements from previous H$\\beta$ campaigns. The high-quality data allow us to construct a velocity-binned delay map for the broad H$\\beta$ line, which shows a symmetric response pattern around the line center, a plausible kinematic signature of virialized motion of the BLR. Combining all the available measurements of H$\\beta$ time lags and the associated mean 5100 {\\AA}...

  8. Emission Lines of Fe XI - XIII in the Extreme Ultraviolet Region

    Science.gov (United States)

    Lepson, Jaan; Beiersdorfer, Peter; Liedahl, Duane; Desai, Priya; Brickhouse, Nancy; Dupree, Andrea; Kahn, Steven

    2009-05-01

    Iron is one of the most abundant heavy elements in extreme ultraviolet spectra of astrophysical and laboratory plasmas, and its various ions radiate profusely in the extreme ultraviolet (EUV) wavelength band. Iron emission in the EUV provides important d iagnostic tools for such properties as plasma temperature and density, and perhaps even magnetic field strength. Despite its importance to astrophysics and magnetic fusion, knowledge of the EUV spectrum of iron is incomplete. Identification of iron emis sion lines is hampered by the paucity of accurate laboratory measurements and the uncertainty of even the best atomic models. As part of a project to measure and compile emission line data in the EUV, we present here spectra and lines of Fe XI - XIII recorded on the Livermore EBIT-II electron beam ion trap in the 50 - 120 åregion. We measured line positions to 0.02 åand relative intensities with an accuracy of one part in twenty. Many new lines are identified and added to the available databa ses. Part of this work was performed under the auspices of the U S Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344 and was supported by NASA's Astronomy and Physics Research and Analysis Program under Con t ract NNH07AF811.

  9. An Extreme, Blueshifted Iron-Line Profile in the Narrow-Line Seyfert 1 PG 1402+261: An Edge-on Accretion Disk or Highly Ionized Absorption?

    Science.gov (United States)

    Reeves, J. N.; Porquet, D.; Turner, T. J.

    2004-11-01

    We report on a short XMM-Newton observation of the radio-quiet narrow-line Seyfert 1 galaxy PG 1402+261. The EPIC X-ray spectrum of PG 1402+261 shows a strong excess of counts between 6 and 9 keV in the rest frame. This feature can be modeled by an unusually strong (equivalent width 2 keV) and very broad (FWHM velocity of 110,000 km s-1) iron K-shell emission line. The line centroid energy at 7.3 keV appears blueshifted with respect to the iron Kα emission band between 6.4 and 6.97 keV, while the blue wing of the line extends to 9 keV in the quasar rest frame. The line profile can be fitted by reflection from the inner accretion disk, but an inclination angle of >60° is required to model the extreme blue wing of the line. Furthermore, the extreme strength of the line requires a geometry whereby the hard X-ray emission from PG 1402+261 above 2 keV is dominated by the pure-reflection component from the disk, while little or none of the direct hard power law is observed. Alternatively, the spectrum above 2 keV may be explained by an ionized absorber, if the column density is sufficiently high (NH>3×1023 cm-2) and if the matter is ionized enough to produce a deep (τ~1) iron K-shell absorption edge at 9 keV. This absorber could originate in a large column density, high-velocity outflow, perhaps similar to those that appear to be observed in several other high accretion rate active galactic nuclei. Further observations, especially at higher spectral resolution, are required to distinguish between the accretion disk reflection and outflow scenarios.

  10. Electron Density Measurements in the National Spherical Torus Experiment Detached Divertor Region Using Stark Broadening of Deuterium Infrared Paschen Emission Lines

    Energy Technology Data Exchange (ETDEWEB)

    Soukhanovskii, V A; Johnson, D W; Kaita, R; Roquemore, A L

    2007-04-27

    Spatially resolved measurements of deuterium Balmer and Paschen line emission have been performed in the divertor region of the National Spherical Torus Experiment using a commercial 0.5 m Czerny-Turner spectrometer. While the Balmer emission lines, Balmer and Paschen continua in the ultraviolet and visible regions have been extensively used for tokamak divertor plasma temperature and density measurements, the diagnostic potential of infrared Paschen lines has been largely overlooked. We analyze Stark broadening of the lines corresponding to 2-n and 3-m transitions with principle quantum numbers n = 7-12 and m = 10-12 using recent Model Microfield Method calculations (C. Stehle and R. Hutcheon, Astron. Astrophys. Supl. Ser. 140, 93 (1999)). Densities in the range (5-50) x 10{sup 19} m{sup -3} are obtained in the recombining inner divertor plasma in 2-6 MW NBI H-mode discharges. The measured Paschen line profiles show good sensitivity to Stark effects, and low sensitivity to instrumental and Doppler broadening. The lines are situated in the near-infrared wavelength domain, where optical signal extraction schemes for harsh nuclear environments are practically realizable, and where a recombining divertor plasma is optically thin. These properties make them an attractive recombining divertor density diagnostic for a burning plasma experiment.

  11. APPLICATION OF THE MOMENT METHODS TO ANALYSIS OF X-RAY DIFFRACTION LINE PROFILE FOR PA1010-BMI SYSTEM

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hongfang; YU Li; ZHANG Lihua; MO Zhishen; MU Zhongchen

    1995-01-01

    Pure X-ray diffraction profiles have been analysed for polyamide 1010 and PA1010-BMI system by means of multipeak fitting resolution of X-ray diffraction. The methods of variance and fourth moment have been applied to determine the particle size and strain values for the paracrystalline materials. The results indicated that both variance and fourth moment of X-ray diffraction line profile yielded approximately the same values of the particle size and the strain. The particle sizes of (100) reflection have been found to decrease with increasing BMI content, whereas the strain values increased.

  12. Broadening of the Spectral Atomic Lines Analysis in High Density Argon Corona Plasma by Using Voigt Profile

    Science.gov (United States)

    Nur, M.; Bonifaci, N.; Denat, A.; Atrazhev, V. M.

    2015-06-01

    Studies of spectrum emission from high density argon plasma corona has been done. The analysis of the boardening of spectral atomic lines of Ar-I profile has been curried out by using an empirical approximation based on a Voigt profile. Full-width at half-maximum (FWHM) of the spectral-lines of 763.5 nm has been determined from atmospheric pressure until liquid state. The study liquid argon was curried out in a variation of temperature from K to 151.2 K and hydrostatics pressure from 2.1 MPa to 6.4 MPa. These pressure gives the densities N∞ (i.e. density very far from ionization zone) a variation from 1.08 1022 to 2.11 1022 cm-3. FWHM of Voigt approximation (Wv) of the line 763,5 nm of 'Ar I for: the emission lamp very low pressure (Wv = 0,160 nm) and our corona discharge at a pressure of MPa (Wv = 0,67 nm) and at a pressure of 9,5 MPa (Wv = 1,16 nm). In gas, corona plasma has been generated from 0.1 MPa to 9.5 MPa. We found that the broadening spectral line increase by increasing densities both for. the spectral-lines of 763.5 nm and 696.5 nm. We concluded that broadening of spectrum cause of Van der Waals force.

  13. Herschel-HIFI observations of high-J CO lines in the NGC 1333 low-mass star-forming region

    CERN Document Server

    Yıldız, U A; Kristensen, L E; Visser, R; Jørgensen, J K; Herczeg, G J; van Kempen, T A; Hogerheijde, M R; Doty, S D; Benz, A O; Bruderer, S; Wampfler, S F; Deul, E; Bachiller, R; Baudry, A; Benedettini, M; Bergin, E; Bjerkeli, P; Blake, G A; Bontemps, S; Braine, J; Caselli, P; Cernicharo, J; Codella, C; Daniel, F; di Giorgio, A M; Dominik, C; Encrenaz, P; Fich, M; Fuente, A; Giannini, T; Goicoechea, J R; de Graauw, Th; Helmich, F; Herpin, F; Jacq, T; Johnstone, D; Larsson, B; Lis, D; Liseau, R; Liu, F -C; Marseille, M; McCoey, C; Melnick, G; Neufeld, D; Nisini, B; Olberg, M; Parise, B; Pearson, J C; Plume, R; Risacher, C; Santiago-Garcia, J; Saraceno, P; Shipman, R; Tafalla, M; Tielens, A G G M; van der Tak, F; Wyrowski, F; Dieleman, P; Jellema, W; Ossenkopf, V; Schieder, R; Stutzki, J; 10.1051/0004-6361/201015119

    2010-01-01

    Herschel-HIFI observations of high-J lines (up to J_u=10) of 12CO, 13CO and C18O are presented toward three deeply embedded low-mass protostars, NGC 1333 IRAS 2A, IRAS 4A, and IRAS 4B, obtained as part of the Water In Star-forming regions with Herschel (WISH) key program. The spectrally-resolved HIFI data are complemented by ground-based observations of lower-J CO and isotopologue lines. The 12CO 10-9 profiles are dominated by broad (FWHM 25-30 km s^-1) emission. Radiative transfer models are used to constrain the temperature of this shocked gas to 100-200 K. Several CO and 13CO line profiles also reveal a medium-broad component (FWHM 5-10 km s^-1), seen prominently in H2O lines. Column densities for both components are presented, providing a reference for determining abundances of other molecules in the same gas. The narrow C18O 9-8 lines probe the warmer part of the quiescent envelope. Their intensities require a jump in the CO abundance at an evaporation temperature around 25 K, thus providing new direct e...

  14. Rfp-Y region polymorphism and Marek's disease resistance in multitrait immunocompetence-selected chicken lines.

    Science.gov (United States)

    Lakshmanan, N; Lamont, S J

    1998-04-01

    Although the influence of the chicken classical MHC in resistance to many diseases is well established, the role of the recently identified, genetically independent, MHC-like region known as Rfp-Y is unclear. The objectives of this study were to analyze the frequencies of DNA polymorphisms of the Rfp-Y region in White Leghorn lines, which were divergently selected in replicate for multitrait immunocompetence, and to determine the association of these polymorphisms with Marek's disease (MD) resistance. Chicks, either with or without herpes virus of turkey (HVT) vaccination, were challenged with 500 ffu of a very virulent Marek's disease virus (Md5) at 2 d of age. The MD-related data were collected for 10 wk. PvuII-digested genomic DNA was hybridized with an Rfp-Y region-specific probe, 18.1. Three Rfp-Y polymorphisms were observed. The frequency of one Rfp-Y polymorphism was significantly different between divergently selected multitrait immunocompetence lines in one replicate only; therefore, the impact of multitrait immunocompetence selection on Rfp-Y polymorphisms is inconclusive. The PvuII defined Rfp-Y region polymorphisms had no association with either innate or vaccine-induced MD resistance to Md5 virus challenge.

  15. Silhouette and spectral line profiles in the special modification of the Kerr black hole geometry generated by quintessential fields

    CERN Document Server

    Schee, Jan

    2016-01-01

    We study optical effects in quintessential Kerr black hole spacetimes corresponding to the limiting case of the equation-of-state parameter $\\omega_{q}=-1/3$ of the quintessence. In dependence on the dimensionless quintessential field parameter $c$, we determine the black hole silhouette and the spectral line profiles of Keplerian disks generated in this special quintessential Kerr geometry, representing an extension of the general modifications of the Kerr geometry introduced recently by Ghasemi-Nodehi and Bambi \\cite{Gha-Bam:2016:EPJC:}. We demonstrate that due to the influence of the parameter $c$, the silhouette is almost homogeneously enlarged, and the spectral line profiles are redshifted with almost conserved shape.

  16. Silhouette and spectral line profiles in the special modification of the Kerr black hole geometry generated by quintessential fields

    Energy Technology Data Exchange (ETDEWEB)

    Schee, Jan; Stuchlik, Zdenek [Silesian University in Opava, Faculty of Philosophy and Science, Institute of Physics and Research Centre for Theoretical Physics and Astrophysics, Opava (Czech Republic)

    2016-11-15

    We study optical effects in quintessential Kerr black hole spacetimes corresponding to the limiting case of the equation-of-state parameter ω{sub q} = -1/3 of the quintessence. In dependence on the dimensionless quintessential field parameter c, we determine the black hole silhouette and the spectral line profiles of Keplerian disks generated in this special quintessential Kerr geometry, representing an extension of the general modifications of the Kerr geometry introduced recently by Ghasemi-Nodehi and Bambi (Eur. Phys. J. C 56:290, 2016). We demonstrate that due to the influence of the parameter c, the silhouette is almost homogeneously enlarged, and the spectral line profiles are redshifted with almost conserved shape. (orig.)

  17. Comparative assessment of maize lines produced by different breeding methods using both microbiological and metabolic profiling tools

    CSIR Research Space (South Africa)

    Barros, E

    2006-02-01

    Full Text Available , F; NMR-based metabolomic study of transgenic maize. Phytochemistry (2004), 65: 3187-3198 2. Rabie, CJ; Lübben, A; Marais, GJ; and Jansen van Vuuren, H (1997) Enumeration of fungi in barley. International Journal of Food Microbiology, 35, 117... Biosciences includes the evaluation of different South African and European maize lines, using microbiological and mycotoxin analysis, as well as metabolic profiling through NMR (Nuclear Magnetic Resonance) analysis. This study shows the results obtained...

  18. A Low-Profile Dual-Band Micro-strip Antenna Having Open-Circuited Strip-line-Stub

    OpenAIRE

    長谷川, 孝明; 羽石, 操

    1986-01-01

    Copyright notice. c1986 IEICE All rights reserved. "A Low-Profile Dual-Band Micro-strip Antenna Having Open-Circuited Strip-line-Stub"Misao HANEISHI, Hidekazu SUGA, Takaaki HASEGAWA.The Transactions of the Institute of Electronics and Communication Engineers of Japan. Section E, English, 1986. Vol. E69 No.11 pp. 1165-1166 許諾No.07RB0055.

  19. The Nuclear Region of Low Luminosity Flat Radio Spectrum Sources. II. Emission-Line Spectra

    CERN Document Server

    Gonçalves, A C

    2004-01-01

    We report on the spectroscopic study of 19 low luminosity Flat Radio Spectrum (LL FRS) sources selected from Marcha's et al. (1996) 200 mJy sample. In the optical, these objects are mainly dominated by the host galaxy starlight. After correcting the data for this effect, we obtain a new set of spectra clearly displaying weak emission lines; such features carry valuable information concerning the excitation mechanisms at work in the nuclear regions of LL FRS sources. We have used a special routine to model the spectra and assess the intensities and velocities of the emission lines; we have analyzed the results in terms of diagnostic diagrams. Our analysis shows that 79% of the studied objects harbour a Low Ionization Nuclear Emission-line Region (or LINER) whose contribution was swamped by the host galaxy starlight. The remaining objects display a higher ionization spectrum, more typical of Seyferts; due to the poor quality of the spectra, it was not possible to identify any possible large Balmer components. T...

  20. Physical Conditions in the Narrow-Line Region of Markarian 3. II. Photoionization Modeling Results

    CERN Document Server

    Collins, Nicholas R; Crenshaw, D Michael; Bruhweiler, Frederick C; Mélendez, Marcio

    2009-01-01

    We have examined the physical conditions in the narrow-line region (NLR) of the Seyfert 2 galaxy Markarian 3, using long-slit spectra obtained with the Hubble Space Telescope/Space Telescope Imaging Spectrograph and photoionization models. We find three components of photoionized gas in the NLR. Two of these components, characterized by emission lines such as [NeV] 3426 and [OIII] 5007, lie within the envelope of the bi-conical region described in our previous kinematic study. A component of lower ionization gas, in which lines such as [OII] 3727 arise, is found to lie outside the bi-cone. Each of these components is irradiated by a power-law continuum which is attenuated by intervening gas, presumably closer to the central source. The radiation incident upon the low ionization gas, external to the bi-cone, is much more heavily absorbed. These absorbers are similar to the intrinsic UV and X-ray absorbers detected in many Seyfert 1 galaxies, which suggests that the collimation of the ionizing radiation occurs ...

  1. Radiation pressure confinement - II. Application to the broad line region in active galactic nuclei

    CERN Document Server

    Baskin, Alexei; Stern, Jonathan

    2014-01-01

    Active galactic nuclei (AGN) are characterized by broad emission lines. The lines show similar properties from the lowest luminosity (10^39 erg/s) to the highest luminosity (10^47 erg/s) AGN. What produces this similarity over such a vast range of 10^8 in luminosity? Photoionization is inevitably associated with momentum transfer to the photoionized gas. Yet, most of the photoionized gas in the Broad Line Region (BLR) follows Keplerian orbits, which suggests that the BLR originates from gas clouds with a large enough column for gravity to dominate. The photoionized surface layer of these clouds must develop a pressure gradient which balances the incident radiation force. We present solutions for the structure of such a hydrostatic photoionized gas layer in the BLR. The gas is stratified, with a low-density highly-ionized surface layer, set by the ambient pressure, a density rise inwards, and a uniform density cooler inner region, where the gas pressure, 2n_ekT, reaches the incident radiation pressure n_gamma,...

  2. Gene-specific DNA methylation profiles and LINE-1 hypomethylation are associated with myocardial infarction risk

    NARCIS (Netherlands)

    Guarrera, Simonetta; Fiorito, Giovanni; Onland-Moret, N Charlotte; Russo, Alessia; Agnoli, Claudia; Allione, Alessandra; Di Gaetano, Cornelia; Mattiello, Amalia; Ricceri, Fulvio; Chiodini, Paolo; Polidoro, Silvia; Frasca, Graziella; Verschuren, Monique W M; Boer, Jolanda M A; Iacoviello, Licia; van der Schouw, Yvonne T; Tumino, Rosario; Vineis, Paolo; Krogh, Vittorio; Panico, Salvatore; Sacerdote, Carlotta; Matullo, Giuseppe

    2015-01-01

    BACKGROUND: DNA methylation profiles are responsive to environmental stimuli and metabolic shifts. This makes DNA methylation a potential biomarker of environmental-related and lifestyle-driven diseases of adulthood. Therefore, we investigated if white blood cells' (WBCs) DNA methylation profiles ar

  3. Evidence of the Link between Broad Emission Line Regions and Accretion Disks in Active Galactic Nuclei

    Institute of Scientific and Technical Information of China (English)

    Yun Xu; Xin-Wu Cao

    2007-01-01

    There is observational evidence that broad-line regions (BLRs) exist in most active galactic nuclei (AGNs), but their origin is still unclear. One scenario is that the BLRs originate from winds accelerated from the hot coronae of the disks, and the winds are suppressed when the black hole is accreting at low rates. This model predicts a relation between (m) ((m) = (M)/(M)Edd) and the FWHM of broad emission lines. We estimate the central black hole masses for a sample of bright AGNs by using their broad Hβ line-widths and optical luminosities. The dimensionless accretion rates (m) = (M)/(M)Edd are derived from the optical continuum luminosities by using two different models: using an empirical relation between the bolometric luminosity Lbol and the optical luminosity ((m) = Lbol/LEdd, a fixed radiative efficiency is adopted); and calculating the optical spectra of accretion disks as a function of (m). We find a significant correlation between the derived (m) and the observed line width of Hβ,FWHM∝ (m)-0.37, which almost overlaps the disk-corona model calculations, if the viscosity α≈ 0.1 - 0.2 is adopted. Our results provide strong evidence for the physical link between the BLRs and accretion disks in AGNs.

  4. Elemental Abundances in the Broad Emission Line Region of Quasars at Redshifts larger than 4

    CERN Document Server

    Dietrich, M; Hamann, F; Heidt, J; Jäger, K; Vestergaard, M; Wagner, S J

    2003-01-01

    We present observations of 11 high redshift quasars ($3.9 \\la z \\la 5.0$) observed with low spectral resolution in the restframe ultraviolet using FORS 1 at the VLT UT 1. The emission-line fluxes of strong permitted and intercombination ultraviolet emission lines are measured to estimate the chemical composition of the line emitting gas. Comparisons to photoionization calculations indicate gas metallicities in the broad emission line region in the range of solar to several times solar. The average of the mean metallicity of each high-z quasar in this sample is $Z/Z_\\odot = 4.3 \\pm 0.3$. Assuming a chemical evolution time scale of $\\tau_{evol} \\simeq 0.5 - 0.8$ Gyrs, we derive a redshift of $z_f \\simeq 6 {\\rm to} 8$ for the onset of the first major star formation episode (H$_o = 65$ km s$^{-1}$ Mpc$^{-1}$, $\\Omega_M = 0.3$, $\\Omega_\\Lambda = 0.7$), corresponding to an age of the universe of several $10^8$ yrs at this epoch. We note that this epoch is also supposed to be the era of re-ionization of the universe...

  5. The broad-line region and dust torus size of the Seyfert 1 galaxy PGC50427

    CERN Document Server

    Nuñez, F Pozo; Westhues, C; Haas, M; Chini, R; Steenbrugge, K; Domínguez, A Barr; Kaderhandt, L; Hackstein, M; Kollatschny, W; Zetzl, M; Hodapp, Klaus W; Murphy, M

    2015-01-01

    We present the results of a three years monitoring campaigns of the $z = 0.024$ type-1 active galactic nucleus (AGN) PGC50427. Through the use of Photometric Reverberation Mapping with broad and narrow band filters, we determine the size of the broad-line emitting region by measuring the time delay between the variability of the continuum and the H$\\alpha$ emission line. The H$\\alpha$ emission line responds to blue continuum variations with an average rest frame lag of $19.0 \\pm 1.23$ days. Using single epoch spectroscopy we determined a broad-line H$\\alpha$ velocity width of 1020 km s$^{-1}$ and in combination with the rest frame lag and adoption a geometric scaling factor $f = 5.5$, we calculate a black hole mass of $M_{BH} \\sim 17 \\times 10^{6} M_{\\odot}$. Using the flux variation gradient method, we separate the host galaxy contribution from that of the AGN to calculate the rest frame 5100\\AA~ luminosity at the time of our monitoring campaign. The rest frame lag and the host-subtracted luminosity permit u...

  6. [IHE ITI-ATNA profile-based solution for the security of regional healthcare information sharing].

    Science.gov (United States)

    Yao, Ye-hong; Zhang, Jian-guo

    2008-09-01

    In designing and implementing regional healthcare information sharing systems, the security problem is a very important issue. According to the Audit Trail and Node Authentication (ATNA) Profile of Integrating the Healthcare Enterprise (IHE) and the practical experiences in several hospitals in Shanghai, a Proxy/Server based security solution for the integration of regional healthcare information sharing systems is proposed, which can solve the cross-platform security problems of integration, providing some security measures such as Central User Authentication, Audit Trail and Node Authentication.

  7. Fast inversion of Zeeman line profiles using central moments. II. Stokes V moments and determination of vector magnetic fields

    Science.gov (United States)

    Mein, P.; Uitenbroek, H.; Mein, N.; Bommier, V.; Faurobert, M.

    2016-06-01

    Context. In the case of unresolved solar structures or stray light contamination, inversion techniques using four Stokes parameters of Zeeman profiles cannot disentangle the combined contributions of magnetic and nonmagnetic areas to the observed Stokes I. Aims: In the framework of a two-component model atmosphere with filling factor f, we propose an inversion method restricting input data to Q , U, and V profiles, thus overcoming ambiguities from stray light and spatial mixing. Methods: The V-moments inversion (VMI) method uses shifts SV derived from moments of V-profiles and integrals of Q2, U2, and V2 to determine the strength B and inclination ψ of a magnetic field vector through least-squares polynomial fits and with very few iterations. Moment calculations are optimized to reduce data noise effects. To specify the model atmosphere of the magnetic component, an additional parameter δ, deduced from the shape of V-profiles, is used to interpolate between expansions corresponding to two basic models. Results: We perform inversions of HINODE SOT/SP data for inclination ranges 0 <ψ< 60° and 120 <ψ< 180° for the 630.2 nm Fe i line. A damping coefficient is fitted to take instrumental line broadening into account. We estimate errors from data noise. Magnetic field strengths and inclinations deduced from VMI inversion are compared with results from the inversion codes UNNOFIT and MERLIN. Conclusions: The VMI inversion method is insensitive to the dependence of Stokes I profiles on the thermodynamic structure in nonmagnetic areas. In the range of Bf products larger than 200 G, mean field strengths exceed 1000 G and there is not a very significant departure from the UNNOFIT results because of differences between magnetic and nonmagnetic model atmospheres. Further improvements might include additional parameters deduced from the shape of Stokes V profiles and from large sets of 3D-MHD simulations, especially for unresolved magnetic flux tubes.

  8. Determination of magnetic fields in broad line region of active galactic nuclei from polarimetric observations

    Science.gov (United States)

    Piotrovich, Mikhail; Silant'ev, Nikolai; Gnedin, Yuri; Natsvlishvili, Tinatin; Buliga, Stanislava

    2017-02-01

    Magnetic fields play an important role in confining gas clouds in the broad line region (BLR) of active galactic nuclei (AGN) and in maintaining the stability of these clouds. Without magnetic fields the clouds would not be stable, and soon after their formation they would expand and disperse. We show that the strength of the magnetic field can be derived from the polarimetric observations. Estimates of magnetic fields for a number of AGNs are based on the observed polarization degrees of broad Hα lines and nearby continuum. The difference between their values allows us to estimate the magnetic field strength in the BLR using the method developed by Silant'ev et al. (2013). Values of magnetic fields in BLR for a number of AGNs have been derived.

  9. Determining the Narrow-Line Region Geometry of Mrk 3 with Gemini/NIFS

    Science.gov (United States)

    Pope, Crystal L.; Fischer, Travis C.; Crenshaw, D. Michael

    2015-01-01

    We present a study of the narrow-line region (NLR) and inner disk of the Seyfert 2 Mrk 3, based on observations from the Gemini Near-Infrared Integral Field Spectrometer (NIFS). Mrk 3 exhibits emission-line knots within the NLR that are in the shape of a backward S, which is likely due to dust/gas spirals in the galaxy's disk that have been illuminated by the AGN's ionizing bicone. With our NIFS observations, we determine the kinematics of Mrk 3 using an automated Bayesian model selection algorithm. Comparing the NLR kinematics measured with NIFS to those previously measured with the Hubble Space Telescope (HST) Space Telescope Imaging Spectrograph (STIS), we are able to test the accuracy of our previous kinematic outflow model.

  10. The Relationship Between Luminosity and Broad-Line Region Size in Active Galactic Nuclei

    DEFF Research Database (Denmark)

    Kaspi, Shai; Maoz, Dan; Netzer, Hagai

    2005-01-01

    of analysis, our results are generally consistent. Assuming a power-law relation R_blr \\propto L^\\alpha, we find the mean best-fitting \\alpha is about 0.67+/-0.05 for the optical continuum and the broad H\\beta luminosity, about 0.56+/-0.05 for the UV continuum luminosity, and about 0.70+/-0.14 for the X......We reinvestigate the relationship between the characteristic broad-line region size (R_blr) and the Balmer emission-line, X-ray, UV, and optical continuum luminosities. Our study makes use of the best available determinations of R_blr for a large number of active galactic nuclei (AGNs) from...

  11. Test of the Formation mechanism of the Broad Line Region in Active Galactic Nuclei

    CERN Document Server

    Czerny, Bozena; Wang, Jian-Min; Karas, Vladimir

    2016-01-01

    The origin of the Broad Line Region (BLR) in active galaxies remains unknown. It seems to be related to the underlying accretion disk but an efficient mechanism is required to rise the material from the disk surface without giving too strong signatures of the outflow in the case of the low ionization lines. We discuss in detail two proposed mechanisms: (i) radiation pressure acting on dust in the disk atmosphere creating a failed wind (ii) the gravitational instability of the underlying disk. We compare the predicted location of the inner radius of the BLR in those two scenarios with the observed position obtained from the reverberation studies of several active galaxies. The failed dusty outflow model well represents the observational data while the predictions of the self-gravitational instability are not consistent with observations. The issue remains why actually we do not see any imprints of the underlying disk instability in the BLR properties.

  12. Effect of the drag force on the orbital motion of the broad-line region clouds

    CERN Document Server

    Khajenabi, Fazeleh

    2016-01-01

    We investigate orbital motion of cold clouds in the broad line region of active galactic nuclei subject to the gravity of a black hole and a force due to a nonisotropic central source and a drag force proportional to the velocity square. The intercloud is described using the standard solutions for the advection-dominated accretion flows. Orbit of a cloud decays because of the drag force, but the typical time scale of falling of clouds onto the central black hole is shorter comparing to the linear drag case. This time scale is calculated when a cloud is moving through a static or rotating intercloud. We show that when the drag force is a quadratic function of the velocity, irrespective of the initial conditions and other input parameters, clouds will generally fall onto the central region much faster than the age of whole system and since cold clouds present in most of the broad line regions, we suggest that mechanisms for continuous creation of the clouds must operate in these systems.

  13. THE GREEN BANK TELESCOPE H II REGION DISCOVERY SURVEY. IV. HELIUM AND CARBON RECOMBINATION LINES

    Energy Technology Data Exchange (ETDEWEB)

    Wenger, Trey V.; Bania, T. M. [Astronomy Department, 725 Commonwealth Avenue, Boston University, Boston, MA 02215 (United States); Balser, Dana S. [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA, 22903-2475 (United States); Anderson, L. D. [Department of Physics, West Virginia University, Morgantown, WV 26506 (United States)

    2013-02-10

    The Green Bank Telescope H II Region Discovery Survey (GBT HRDS) found hundreds of previously unknown Galactic regions of massive star formation by detecting hydrogen radio recombination line (RRL) emission from candidate H II region targets. Since the HRDS nebulae lie at large distances from the Sun, they are located in previously unprobed zones of the Galactic disk. Here, we derive the properties of helium and carbon RRL emission from HRDS nebulae. Our target sample is the subset of the HRDS that has visible helium or carbon RRLs. This criterion gives a total of 84 velocity components (14% of the HRDS) with helium emission and 52 (9%) with carbon emission. For our highest quality sources, the average {sup 4}He{sup +}/H{sup +} abundance ratio by number, (y {sup +}), is 0.068 {+-} 0.023(1{sigma}). This is the same ratio as that measured for the sample of previously known Galactic H II regions. Nebulae without detected helium emission give robust y {sup +} upper limits. There are 5 RRL emission components with y {sup +} less than 0.04 and another 12 with upper limits below this value. These H II regions must have either a very low {sup 4}He abundance or contain a significant amount of neutral helium. The HRDS has 20 nebulae with carbon RRL emission but no helium emission at its sensitivity level. There is no correlation between the carbon RRL parameters and the 8 {mu}m mid-infrared morphology of these nebulae.

  14. Virilization of the Broad Line Region in Active Galactic Nuclei - connection between shifts and widths of broad emission lines

    CERN Document Server

    Jonic, Sanja; Ilic, Dragana; Popovic, Luka C

    2016-01-01

    We investigate the virilization of the emission lines Hbeta and Mg II in the sample of 287 Type 1 Active Galactic Nuclei taken from the Sloan Digital Sky Survey database. We explore the connections between the intrinsic line shifts and full widths at different levels of maximal intensity. We found that: (i) Hbeta seems to be a good virial estimator of black hole masses, and an intrinsic redshift of Hbeta is dominantly caused by the gravitational effect, (ii) there is an anti-correlation between the redshift and width of the wings of the Mg II line, (iii) the broad Mg II line can be used as virial estimator only at 50% of the maximal intensity, while the widths and intrinsic shifts of the line wings can not be used for this purpose.

  15. Time Ordering Effects on Hydrogen Zeeman-Stark Line Profiles in Low-Density Magnetized Plasmas

    Directory of Open Access Journals (Sweden)

    J. Rosato

    2010-01-01

    Full Text Available Stark broadening of hydrogen lines is investigated in low-density magnetized plasmas, at typical conditions of magnetic fusion experiments. The role of time ordering is assessed numerically, by using a simulation code accounting for the evolution of the microscopic electric field generated by the charged particles moving at the vicinity of the atom. The Zeeman effect due to the magnetic field is also retained. Lyman lines with a low principal quantum number n are first investigated, for an application to opacity calculations; next Balmer lines with successively low and high principal quantum numbers are considered for diagnostic purposes. It is shown that neglecting time ordering results in a dramatic underestimation of the Stark effect on the low-n lines. Another conclusion is that time ordering becomes negligible only when ion dynamics effects vanish, as shown in the case of high-n lines.

  16. Photoionization Models of the H_2 Emission of the Narrow Line Region of AGNs

    Science.gov (United States)

    Aleman, I.; Gruenwald, R.

    2011-05-01

    The excitation mechanism of the narrow line region (NLR) of AGNs is still an open question. Excitation by UV radiation from O and B stars, x-rays from the central black hole, shock from supernovae or jets, or a combination of these mechanisms have been suggested. In the present work, we use photoionization models to study the excitation mechanisms of the H_2 infrared emission lines in the NLR. In the literature, analyzes of the H_2 emission have been done assuming that the molecules is present only in neutral regions (photodissociation regions, x-ray-dominated regions, or shocks; Veilleux et al. 1997, Krabbe et al. 2000, Rigopoulou et al. 2002, Rodriguez-Ardila et al. 2004, 2005, and Davies et al. 2005). However, they are not conclusive. In previous work (Aleman & Gruenwald 2004, 2011), we show that the H_2 emission from the ionized region of PNe can be significant for planetary nebulae (PNe) with hot central stars (T⋆ > 150000 K). Such stars produce copious amounts of high energy photons, which create an extended partially ionized region that favors the H_2 survival. The conditions in the NLR are similar to those in PNe with hot central stars, so we can expect that the H_2 emission might also be important. We obtain and analyze a grid of photoionization models for different NRL parameters. We study the resulting H_2 density and emission, as well as, the formation, destruction, excitation, and de-excitation mechanisms. The higher values observed for the H_2 1-0 S(1)/Brγ ratio cannot be reproduced by our models. The calculated ratios are between 10^-8 and 10^-1, while the observational ration can be as high as 10. The calculated ratio is strongly anti-correlated with the ionization parameter (U) and only models with U<10-3 result in ratios inside the observational range. We show that the NLR is an environment more hostile to the H_2 molecule than the ionized region of PNe. Another interesting result of our calculations is that the H_2 formation on grain surfaces

  17. Railroad Lines, Railroads in 18 county region in South Georgia, Published in 1999, 1:7200 (1in=600ft) scale, Southern Georgia Regional Commission.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Railroad Lines dataset, published at 1:7200 (1in=600ft) scale as of 1999. It is described as 'Railroads in 18 county region in South Georgia'. Data by this...

  18. LINES

    Directory of Open Access Journals (Sweden)

    Minas Bakalchev

    2015-10-01

    Full Text Available The perception of elements in a system often creates their interdependence, interconditionality, and suppression. The lines from a basic geometrical element have become the model of a reductive world based on isolation according to certain criteria such as function, structure, and social organization. Their traces are experienced in the contemporary world as fragments or ruins of a system of domination of an assumed hierarchical unity. How can one release oneself from such dependence or determinism? How can the lines become less “systematic” and forms more autonomous, and less reductive? How is a form released from modernistic determinism on the new controversial ground? How can these elements or forms of representation become forms of action in the present complex world? In this paper, the meaning of lines through the ideas of Le Corbusier, Leonidov, Picasso, and Hitchcock is presented. Spatial research was made through a series of examples arising from the projects of the architectural studio “Residential Transformations”, which was a backbone for mapping the possibilities ranging from playfulness to exactness, as tactics of transformation in the different contexts of the contemporary world.

  19. Does the inner broad-line region dim down when the power turns up?. [Seyfert 1 galaxy NGC 5548

    Science.gov (United States)

    Sparke, Linda S.

    1993-01-01

    The temporal correlations of continuum and broad emission-line fluxes from the Seyfert galaxy NGC 5548 as measured during the 1989 monitoring campaign show two related peculiarities: first, some of the crosscorrelations of line and continuum flux appear steeper on the negative time lag side than the continuum autocorrelation itself; then, the autocorrelation of the line flux is sometimes more sharply peaked than the continuum autocorrelation function. These are here interpreted as evidence that conditions in the inner part of the broad-line region are such that some emission lines decrease in intensity as the continuum strengthens.

  20. A sub-kpc-scale binary AGN with double narrow-line regions

    CERN Document Server

    Woo, Jong-Hak; Husemann, Bernd; Komossa, S; Park, Daeseong; Bennert, Vardha

    2014-01-01

    We present the kinematic properties of a type-2 QSO, SDSS J132323.33-015941.9 at z~0.35, based on the analysis of Very Large Telescope integral field spectroscopy and Hubble Space Telescope (HST) imaging, which suggest that the target is a binary active galactic nucleus (AGN) with double narrow-line regions. The QSO features double-peaked emission lines ([OIII] and Hb) which can be decomposed into two kinematic components. The flux-weighted centroids of the blue and red components are separated by ~0.2" (0.8 kpc in projection) and coincide with the location of the two stellar cores detected in the HST broad-band images, implying that both stellar cores host an active black hole. The line-of-sight velocity of the blue component is comparable to the luminosity-weighted velocity of stars in the host galaxy while the red component is redshifted by ~240 km/s, consistent with typical velocity offsets of two cores in a late stage of a galaxy merger. If confirmed, the target is one of the rare cases of sub-kpc scale ...

  1. Singular surfaces in the open field line region of a diverted tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Reiman, A.

    1995-05-01

    The structure of the open field lines of a slightly nonaxisymmetric, poloidally diverted tokamak is explored by numerical integration of the field line equations for a simple model field. In practice, the nonaxisymmetry could be produced self-consistently by the nonlinear evolution of a free-boundary MHD mode, or it could be produced by field errors, or it could be imposed externally by design. In the presence of a nonaxisymmetric perturbation, the tokamak is shown to develop open field line regions of differing topology separated by singular surfaces. It is argued that the singular surfaces can be expected to play a role analogous to that of rational toroidal flux surfaces, in terms of constraining ideal MHD perturbations and thus constraining the free-energy that can be tapped by ideal MHD instabilities. The possibility of active control of free-boundary instabilities by means of currents driven on the open singular surfaces, which are directly accessible from the divertor plates, is discussed. Also discussed is the possibility of early detection of imminent disruptions through localized measurement of the singular surface currents.

  2. First Detection of the [OIII] 88 micron Line at High Redshifts: Characterizing the Starburst and Narrow Line Regions in Extreme Luminosity Systems

    CERN Document Server

    Ferkinhoff, C; Nikola, T; Parshley, S C; Stacey, G J; Benford, D J; Staguhn, J G

    2010-01-01

    We have made the first detections of the 88 micron [OIII] line from galaxies in the early Universe, detecting the line from the lensed AGN/starburst composite systems APM 08279+5255 at z = 3.911 and SMM J02399-0136 at z = 2.8076. The line is exceptionally bright from both systems, with apparent (lensed) luminosities ~10^11 L_solar. For APM 08279, the [OIII] line flux can be modeled in a star formation paradigm, with the stellar radiation field dominated by stars with effective temperatures, Teff >36,000 K, similar to the starburst found in M82. The model implies ~35% of the total far-IR luminosity of the system is generated by the starburst, with the remainder arising from dust heated by the AGN. The 88 micron line can also be generated in the narrow line region of the AGN if gas densities are around a few 1000 cm-3. For SMM J02399 the [OIII] line likely arises from HII regions formed by hot (Teff >40,000 K) young stars in a massive starburst that dominates the far-IR luminosity of the system. The present wor...

  3. Application of artificial neural networks to a nanoflare model of active region emission line radiance

    CERN Document Server

    Bazarghan, M; Innes, D E; Karami, E; Solanki, S K

    2008-01-01

    Context. Nanoflares are small impulsive bursts of energy that blend with and possibly make up much of the solar background emission. Determining their frequency and energy input is central to understanding the heating of the solar corona. One method is to extrapolate the energy frequency distribution of larger individually observed flares to lower energies. Only if the power law exponent is greater than 2, is it considered possible that nanoflares contribute significantly to the energy input. Aims. Time sequences of ultraviolet line radiances observed in the corona of an active region are modelled with the aim of determining the power law exponent of the nanoflare energy distribution. Methods. A simple nanoflare model based on three key parameters (the flare rate, the flare duration time, and the power law exponent of the flare energy frequency distribution) is used to simulate emission line radiances from the ions Fe XIX, Ca XIII, and Si iii, observed by SUMER in the corona of an active region as it rotates ...

  4. Kinematics of the Narrow-Line Region in the Seyfert 2 Galaxy Mrk 3

    CERN Document Server

    Ruiz, J R; Krämer, S B; Bower, G A; Gull, T R; Hutchings, J B; Kaiser, M E; Weistrop, D; Ruiz, Jose R.

    2001-01-01

    We present measurements of radial velocities for the narrow-line region gas (NLR) in the Seyfert 2 galaxy Mrk 3 out to ~1 kpc from the nucleus. The observations consist of two datasets, both using the Space Telescope Imaging Spectrograph on board the Hubble Space Telescope: 1) An [O III] slitless spectrum with the G430M grating of the inner 3" around the nucleus, and 2) a long-slit observation centered on the nucleus (PA = 71 deg) using the G430L grating and the 52" x 0".1 aperture. Our results produce radial velocity maps of the emission-line gas. These maps indicate general trends in the gas motion, which include: blueshifts and redshifts on either side of the nucleus, steep velocity rises from systemic up to ~ +/-700 km/s taking place in the inner 0".3 (0.8 kpc) both east and west of the nucleus, gradual velocity descents back to near-systemic values from 0".3-1".0, slightly uneven velocity amplitudes on each side of the nucleus, and narrow velocity ranges over the entire observed region. When fitted to ki...

  5. Magnetically elevated accretion disks in active galactic nuclei: broad emission line regions and associated star formation

    Science.gov (United States)

    Begelman, Mitchell C.; Silk, Joseph

    2016-10-01

    We propose that the accretion disks fueling active galactic nuclei are supported vertically against gravity by a strong toroidal (φ -direction) magnetic field that develops naturally as the result of an accretion disk dynamo. The magnetic pressure elevates most of the gas carrying the accretion flow at R to large heights z ˜ 0.1 R and low densities, while leaving a thin dense layer containing most of the mass - but contributing very little accretion - around the equator. We show that such a disk model leads naturally to the formation of a broad emission line region through thermal instability. Extrapolating to larger radii, we demonstrate that local gravitational instability and associated star formation are strongly suppressed compared to standard disk models for AGN, although star formation in the equatorial zone is predicted for sufficiently high mass supply rates. This new class of accretion disk models thus appears capable of resolving two longstanding puzzles in the theory of AGN fueling: the formation of broad emission line regions and the suppression of fragmentation thought to inhibit accretion at the required rates. We show that the disk of stars that formed in the Galactic Center a few million years ago could have resulted from an episode of magnetically elevated accretion at ˜0.1 of the Eddington limit.

  6. On-line Education Initiatives to Galvanize Climate Mitigation in the Great Lakes Region

    Science.gov (United States)

    Mooney, M. E.; Ackerman, S. A.

    2014-12-01

    The Cooperative Institute for Meteorological Satellite Studies (CIMSS) is supporting two different on-line education initiatives that teach about climate change while emphasizing informed and effective responses. The first is an on-line introductory level course for undergraduate students (http://c3.ssec.wisc.edu/) offered through the University of Wisconsin-Madison Atmospheric and Oceanic Sciences (AOS) department. Along with a lighter carbon footprint and the convenience of web-based access, students interact via Drupal forums, Google hangouts and twitter. Activities include several pedagogical tools with sustainability-related content and a final project requiring a discussion of regionally relevant mitigation responses to achieve low emission scenarios for assigned locations. The other initiative is a MOOC (massive open online course) focusing on the changing weather and climate in the Great Lakes Region. This 4-week course is set to launch February 23 2015. One of the primary goals of this MOOC will be having participants change four habits, one per week. Each behavior change will provide a personal benefit to participating individuals while also helping to mitigate the collective impacts of climate change. This presentation will share strategies and insights from both projects.

  7. Gamma-Gamma Absorption in the Broad Line Region Radiation Fields of Gamma-Ray Blazars

    CERN Document Server

    Boettcher, Markus

    2016-01-01

    The expected level of gamma-gamma absorption in the Broad Line Region (BLR) radiation field of gamma-ray loud Flat Spectrum Radio Quasars (FSRQs)is evaluated as a function of the location of the gamma-ray emission region. This is done self-consistently with parameters inferred from the shape of the spectral energy distribution (SED) in a single-zone leptonic EC-BLR model scenario. We take into account all geometrical effects both in the calculation of the gamma-gamma opacity and the normalization of the BLR radiation energy density. As specific examples, we study the FSRQs 3C279 and PKS 1510-089, keeping the BLR radiation energy density at the location of the emission region fixed at the values inferred from the SED. We confirm previous findings that the optical depth due to $\\gamma\\gamma$ absorption in the BLR radiation field exceeds unity for both 3C279 and PKS 1510-089 for locations of the gamma-ray emission region inside the inner boundary of the BLR. It decreases monotonically, with distance from the cen...

  8. The Green Bank Telescope H II Region Discovery Survey: IV. Helium and Carbon Recombination Lines

    CERN Document Server

    Wenger, Trey V; Balser, Dana S; Anderson, L D

    2012-01-01

    The Green Bank Telescope H II Region Discovery Survey (GBT HRDS) found hundreds of previously unknown Galactic regions of massive star formation by detecting hydrogen radio recombination line (RRL) emission from candidate H II region targets. Since the HRDS nebulae lie at large distances from the Sun, they are located in previously unprobed zones of the Galactic disk. Here we derive the properties of helium and carbon RRL emission from HRDS nebulae. Our target sample is the subset of the HRDS that has visible helium or carbon RRLs. This criterion gives a total of 84 velocity components (14% of the HRDS) with helium emission and 52 (9%) with carbon emission. For our highest quality sources, the average ionic He-4+/H+ abundance ratio by number, , is 0.068 +/- 0.023 (1-sigma). This is the same ratio as that measured for the sample of previously known Galactic H II regions. Nebulae without detected helium emission give robust y+ upper limits. There are 5 RRL emission components with y+ less than 0.04 and another ...

  9. Comparison of Return Stroke Current Profiles for Transmission-Line-Type and Traveling-Current-Source-Type Models

    Directory of Open Access Journals (Sweden)

    J.O. Adepitan

    2012-05-01

    Full Text Available The study is aimed at determining the dependence of the current along a channel on the model used, assuming the same base current. We compared three transmission-line-type models, namely: Transmission Line (TL, Modified Transmission Line with Linear decay, Modified Transmission Line with Exponential decay and two traveling-current-source-type models: Bruce-Golde (BG and Traveling Current Source (TCS models. The current profiles along the channel at different heights predicted by these models are presented and discussed. Comparison is based on the assumption that all the models have the same base current. It was found that at low heights and within a time window frame of 15 :s, the currents of the transmission-line-type models predict a zero value at one time or the other with a maximum turning point following some 1:s after. A linear relationship is predicted between the current peak and the channel height. A discontinuity of current peak was observed at high heights. No zero value of current was recorded in case of TCS both at low and high channel heights.

  10. Gamma-ray opacity of the anisotropic stratified broad-line regions in blazars

    Science.gov (United States)

    Abolmasov, Pavel; Poutanen, Juri

    2016-09-01

    The GeV-range spectra of blazars are shaped not only by non-thermal emission processes internal to the relativistic jet but also by external pair-production absorption on the thermal emission of the accretion disc and the broad-line region (BLR). For the first time, we compute here the pair-production opacities in the GeV range produced by a realistic BLR accounting for the radial stratification and radiation anisotropy. Using photoionization modelling with the CLOUDY code, we calculate a series of BLR models of different sizes, geometries, cloud densities, column densities and metallicities. The strongest emission features in the model BLR are Lyα and He II Lyα. Contribution of recombination continua is smaller, especially for hydrogen, because Ly continuum is efficiently trapped inside the large optical depth BLR clouds and converted to Lyman emission lines and higher-order recombination continua. The largest effects on the gamma-ray opacity are produced by the BLR geometry and localization of the gamma-ray source. We show that when the gamma-ray source moves further from the central source, all the absorption details move to higher energies and the overall level of absorption drops because of decreasing incidence angles between the gamma-rays and BLR photons. The observed positions of the spectral breaks can be used to measure the geometry and the location of the gamma-ray emitting region relative to the BLR. Strong dependence on geometry means that the soft photons dominating the pair-production opacity may be actually produced by a different population of BLR clouds than the bulk of the observed broad line emission.

  11. Gamma-ray opacity of the anisotropic stratified broad-line regions in blazars

    Science.gov (United States)

    Abolmasov, Pavel; Poutanen, Juri

    2017-01-01

    The GeV-range spectra of blazars are shaped not only by non-thermal emission processes internal to the relativistic jet but also by external pair-production absorption on the thermal emission of the accretion disc and the broad-line region (BLR). For the first time, we compute here the pair-production opacities in the GeV range produced by a realistic BLR accounting for the radial stratification and radiation anisotropy. Using photoionization modelling with the CLOUDY code, we calculate a series of BLR models of different sizes, geometries, cloud densities, column densities and metallicities. The strongest emission features in the model BLR are Ly α and He II Ly α. Contribution of recombination continua is smaller, especially for hydrogen, because Ly continuum is efficiently trapped inside the large optical depth BLR clouds and converted to Lyman emission lines and higher order recombination continua. The largest effects on the gamma-ray opacity are produced by the BLR geometry and localization of the gamma-ray source. We show that when the gamma-ray source moves further from the central source, all the absorption details move to higher energies and the overall level of absorption drops because of decreasing incidence angles between the gamma-rays and BLR photons. The observed positions of the spectral breaks can be used to measure the geometry and the location of the gamma-ray emitting region relative to the BLR. Strong dependence on geometry means that the soft photons dominating the pair-production opacity may be actually produced by a different population of BLR clouds than the bulk of the observed broad line emission.

  12. Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis.

    Science.gov (United States)

    Kogita, Akihiro; Yoshioka, Yasumasa; Sakai, Kazuko; Togashi, Yosuke; Sogabe, Shunsuke; Nakai, Takuya; Okuno, Kiyotaka; Nishio, Kazuto

    2015-02-27

    Intra- and inter-tumor heterogeneity may hinder personalized molecular-target treatment that depends on the somatic mutation profiles. We performed mutation profiling of formalin-fixed paraffin embedded tumors of multi-regional colon cancer and characterized the consequences of intra- and inter-tumor heterogeneity and metastasis using targeted re-sequencing. We performed targeted re-sequencing on multiple spatially separated samples obtained from multi-regional primary colon carcinoma and associated metastatic sites in two patients using next-generation sequencing. In Patient 1 with four primary tumors (P1-1, P1-2, P1-3, and P1-4) and one liver metastasis (H1), mutually exclusive pattern of mutations was observed in four primary tumors. Mutations in primary tumors were identified in three regions; KARS (G13D) and APC (R876*) in P1-2, TP53 (A161S) in P1-3, and KRAS (G12D), PIK3CA (Q546R), and ERBB4 (T272A) in P1-4. Similar combinatorial mutations were observed between P1-4 and H1. The ERBB4 (T272A) mutation observed in P1-4, however, disappeared in H1. In Patient 2 with two primary tumors (P2-1 and P2-2) and one liver metastasis (H2), mutually exclusive pattern of mutations were observed in two primary tumors. We identified mutations; KRAS (G12V), SMAD4 (N129K, R445*, and G508D), TP53 (R175H), and FGFR3 (R805W) in P2-1, and NRAS (Q61K) and FBXW7 (R425C) in P2-2. Similar combinatorial mutations were observed between P2-1 and H2. The SMAD4 (N129K and G508D) mutations observed in P2-1, however, were nor detected in H2. These results suggested that different clones existed in primary tumors and metastatic tumor in Patient 1 and 2 likely originated from P1-4 and P2-1, respectively. In conclusion, we detected the muti-clonalities between intra- and inter-tumors based on mutational profiling in multi-regional colon cancer using next-generation sequencing. Primary region from which metastasis originated could be speculated by mutation profile. Characterization of inter- and

  13. REVERBERATION AND PHOTOIONIZATION ESTIMATES OF THE BROAD-LINE REGION RADIUS IN LOW-z QUASARS

    Energy Technology Data Exchange (ETDEWEB)

    Negrete, C. Alenka [Instituto Nacional de Astrofisica, Optica y Electronica (Mexico); Dultzin, Deborah [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico (Mexico); Marziani, Paola [INAF, Astronomical Observatory of Padova, I-35122 Padova (Italy); Sulentic, Jack W., E-mail: cnegrete@inaoep.mx, E-mail: deborah@astro.unam.mx, E-mail: paola.marziani@oapd.inaf.it, E-mail: sulentic@iaa.es [Instituto de Astrofisica de Andalucia, E-18008 Granada (Spain)

    2013-07-01

    Black hole mass estimation in quasars, especially at high redshift, involves the use of single-epoch spectra with signal-to-noise ratio and resolution that permit accurate measurement of the width of a broad line assumed to be a reliable virial estimator. Coupled with an estimate of the radius of the broad-line region (BLR) this yields the black hole mass M{sub BH}. The radius of the BLR may be inferred from an extrapolation of the correlation between source luminosity and reverberation-derived r{sub BLR} measures (the so-called Kaspi relation involving about 60 low-z sources). We are exploring a different method for estimating r{sub BLR} directly from inferred physical conditions in the BLR of each source. We report here on a comparison of r{sub BLR} estimates that come from our method and from reverberation mapping. Our ''photoionization'' method employs diagnostic line intensity ratios in the rest-frame range 1400-2000 A (Al III {lambda}1860/Si III] {lambda}1892, C IV {lambda}1549/Al III {lambda}1860) that enable derivation of the product of density and ionization parameter with the BLR distance derived from the definition of the ionization parameter. We find good agreement between our estimates of the density, ionization parameter, and r{sub BLR} and those from reverberation mapping. We suggest empirical corrections to improve the agreement between individual photoionization-derived r{sub BLR} values and those obtained from reverberation mapping. The results in this paper can be exploited to estimate M{sub BH} for large samples of high-z quasars using an appropriate virial broadening estimator. We show that the width of the UV intermediate emission lines are consistent with the width of H{beta}, thereby providing a reliable virial broadening estimator that can be measured in large samples of high-z quasars.

  14. Line Shape Parameters of Water Vapor Transitions in the 3645-3975 cm^{-1} Region

    Science.gov (United States)

    Devi, V. Malathy; Benner, D. Chris; Gamache, Robert R.; Vispoel, Bastien; Renaud, Candice L.; Smith, Mary Ann H.; Sams, Robert L.; Blake, Thomas A.

    2017-06-01

    A Bruker IFS 120HR Fourier transform spectrometer (FTS) at the Pacific Northwest National Laboratory (PNNL) in Richland, Washington was used to record a series of spectra in the regions of the ν_1 and ν_3 bands of H_2O. The samples included low pressures of pure H_2O as well as H_2O broadened by air at different pressures, temperatures and volume mixing ratios. We fit simultaneously 16 high-resolution (0.008 cm^{-1}), high S/N ratio absorption spectra recorded at 268, 296 and 353 K (L=19.95 cm), employing a multispectrum fitting technique to retrieve accurate line positions, relative intensities, Lorentz air-broadened half-width and pressure-shift coefficients and their temperature dependences for more than 220 H_2O transitions. Self-broadened half-width and self-shift coefficients were measured for over 100 transitions. For select sets of transition pairs for the H_2O-air system we determined collisional line mixing coefficients via the off-diagonal relaxation matrix element formalism, and we also measured speed dependence parameters for 85 transitions. Modified Complex Robert Bonamy (MCRB) calculations of the half-widths, line shifts, and temperature dependences were made for self-, N_2-, O_2-, and air-broadening. The measurements and calculations are compared with each other and with similar parameters reported in the literature. D. C. Benner, C. P. Rinsland, V. Malathy Devi, M. A. H. Smith, D. Atkins, JQSRT 53 (1995) 705-721. A. Levy, N. Lacome, C. Chackerian, Collisional line mixing, in Spectroscopy of the Earth's Atmosphere and Interstellar Medium, Academic Press, Inc., Boston (1992) 261-337.

  15. Systematic Blueshift of Line Profiles in the Type IIn Supernova 2010jl: Evidence for Post-Shock Dust Formation?

    CERN Document Server

    Smith, Nathan; Filippenko, Alexei V; Cooper, Michael C; Matheson, Thomas; Bian, Fuyan; Weiner, Benjamin J; Comerford, Julia M

    2011-01-01

    Type IIn SNe show spectral evidence for strong interaction between their blast wave and dense circumstellar material (CSM) around the progenitor star. SN2010jl was the brightest core-collapse SN in 2010, and it was a Type IIn explosion with strong CSM interaction. Andrews et al. recently reported evidence for an IR excess in SN2010jl, indicating either new dust formation or the heating of CSM dust in an IR echo. Here we report multi-epoch spectra of SN2010jl that reveal the tell-tale signature of new dust formation: emission-line profiles becoming systematically more blueshifted as the red side of the line is blocked by increasing extinction. The effect is seen clearly in the intermediate-width (400--4000 km/s) component of H$\\alpha$ beginning roughly 30d after explosion. Moreover, we present near-IR spectra demonstrating that the asymmetry in the hydrogen-line profiles is wavelength dependent, appearing more pronounced at shorter wavelengths. This evidence suggests that new dust grains had formed quickly in ...

  16. Quantitative profiling of housekeeping and Epstein-Barr virus gene transcription in Burkitt lymphoma cell lines using an oligonucleotide microarray

    Directory of Open Access Journals (Sweden)

    Niggli Felix K

    2006-06-01

    Full Text Available Abstract Background The Epstein-Barr virus (EBV is associated with lymphoid malignancies, including Burkitt's lymphoma (BL, and can transform human B cells in vitro. EBV-harboring cell lines are widely used to investigate lymphocyte transformation and oncogenesis. Qualitative EBV gene expression has been extensively described, but knowledge of quantitative transcription is lacking. We hypothesized that transcription levels of EBNA1, the gene essential for EBV persistence within an infected cell, are similar in BL cell lines. Results To compare quantitative gene transcription in the BL cell lines Namalwa, Raji, Akata, Jijoye, and P3HR1, we developed an oligonucleotide microarray chip, including 17 housekeeping genes, six latent EBV genes (EBNA1, EBNA2, EBNA3A, EBNA3C, LMP1, LMP2, and four lytic EBV genes (BZLF1, BXLF2, BKRF2, BZLF2, and used the cell line B95.8 as a reference for EBV gene transcription. Quantitative polymerase chain reaction assays were used to validate microarray results. We found that transcription levels of housekeeping genes differed considerably among BL cell lines. Using a selection of housekeeping genes with similar quantitative transcription in the tested cell lines to normalize EBV gene transcription data, we showed that transcription levels of EBNA1 were quite similar in very different BL cell lines, in contrast to transcription levels of other EBV genes. As demonstrated with Akata cells, the chip allowed us to accurately measure EBV gene transcription changes triggered by treatment interventions. Conclusion Our results suggest uniform EBNA1 transcription levels in BL and that microarray profiling can reveal novel insights on quantitative EBV gene transcription and its impact on lymphocyte biology.

  17. Metabolism and fatty acid profile in fat and lean rainbow trout lines fed with vegetable oil: effect of carbohydrates.

    Directory of Open Access Journals (Sweden)

    Biju Sam Kamalam

    Full Text Available The present study investigated the effect of dietary carbohydrates on metabolism, with special focus on fatty acid bioconversion and flesh lipid composition in two rainbow trout lines divergently selected for muscle lipid content and fed with vegetable oils. These lines were chosen based on previously demonstrated potential differences in LC-PUFA synthesis and carbohydrate utilization. Applying a factorial study design, juvenile trout from the lean (L and the fat (F line were fed vegetable oil based diets with or without gelatinised starch (17.1% for 12 weeks. Blood, liver, muscle, intestine and adipose tissue were sampled after the last meal. Feed intake and growth was higher in the L line than the F line, irrespective of the diet. Moderate postprandial hyperglycemia, strong induction of hepatic glucokinase and repressed glucose-6-phosphatase transcripts confirmed the metabolic response of both lines to carbohydrate intake. Further at the transcriptional level, dietary carbohydrate in the presence of n-3 LC-PUFA deficient vegetable oils enhanced intestinal chylomicron assembly, disturbed hepatic lipid metabolism and importantly elicited a higher response of key desaturase and elongase enzymes in the liver and intestine that endorsed our hypothesis. PPARγ was identified as the factor mediating this dietary regulation of fatty acid bioconversion enzymes in the liver. However, these molecular changes were not sufficient to modify the fatty acid composition of muscle or liver. Concerning the genotype effect, there was no evidence of substantial genotypic difference in lipid metabolism, LC-PUFA synthesis and flesh fatty acid profile when fed with vegetable oils. The minor reduction in plasma glucose and triglyceride levels in the F line was linked to potentially higher glucose and lipid uptake in the muscle. Overall, these data emphasize the importance of dietary macro-nutrient interface in evolving fish nutrition strategies.

  18. ASTER based velocity profile of glaciers in the Nanga Parbat region, western Himalaya

    Science.gov (United States)

    Parkes, A. T.; Haritashya, U. K.

    2011-12-01

    Glaciers, in general, are highly sensitive to climate fluctuations making them important indicators of climate change. Overall, lack of data on this region is troubling for the amount of hydrological importance and climatic forecasts these glaciers hold. Therefore, this study aims to measure glacier velocity on selected glaciers using cross-correlation techniques. One of the main problems with determining the amount of loss or perhaps gain in glacier mass is determining their velocity. The Himalayan glaciers are inaccessible in most areas and field measurements can be impossible, which creates a problem when determining the velocity of glaciers. Consequently, we generated velocity profiles of glaciers in the Nanga Parbat region of the western Himalaya using 2009 and 2010 ASTER satellite data. Our glacier fluctuation study have shown oscillating behavior of these glaciers; however, our preliminary velocity result indicates high velocity on most of these glaciers. These results are the first ever velocity profile generated for this region and would be able to help understand glacier dynamics in a much more comprehensive manner.

  19. Density Profiles in Molecular Cloud Cores Associated with High-Mass Star-Forming Regions

    CERN Document Server

    Pirogov, Lev E

    2009-01-01

    Radial density profiles for the sample of dense cores associated with high-mass star-forming regions from southern hemisphere have been derived using the data of observations in continuum at 250 GHz. Radial density profiles for the inner regions of 16 cores (at distances $\\la 0.2-0.8$ pc from the center) are close on average to the $\\rho\\propto r^{-\\alpha}$ dependence, where $\\alpha=1.6\\pm 0.3$. In the outer regions density drops steeper. An analysis with various hydrostatic models showed that the modified Bonnor-Ebert model, which describes turbulent sphere confined by external pressure, is preferable compared with the logotrope and polytrope models practically in all cases. With a help of the Bonnor-Ebert model, estimates of central density in a core, non-thermal velocity dispersion and core size are obtained. The comparison of central densities with the densities derived earlier from the CS modeling reveals differences in several cases. The reasons of such differences are probably connected with the presen...

  20. Drug sensitivity and drug resistance profiles of human intrahepatic cholangiocarcinoma cell lines

    Institute of Scientific and Technical Information of China (English)

    Nisana Tepsiri; Liengchai Chaturat; Banchob Sripa; Wises Namwat; Sopit Wongkham; Vajarabhongsa Bhudhisawasdi; Wichittra Tassaneeyakul

    2005-01-01

    AIM: To study the effect of a number of chemotherapeutic drugs on five human intrahepatic cholangiocarcinoma (CCA) cell lines. The expressions of genes that have been proposed to influence the resistance of chemotherapeutic drugs including thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), glutathione-S-transferase P1 (GSTP1), multidrug resistance protein (MDR1) and multidrug resistance-associated proteins (MRPs) were also determined.METHODS: Five human CCA cell lines (KKU-100, KKU M055, KKU-M156, KKU-M214 and KKU-OCA17) weretreated with various chemotherapeutic drugs and growth inhibition was determined by 3-(4,5-dimethylthiazol-2-yl)5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay. Semi-quantitative levels of gene expression were determined by a reverse transcriptase polymerase chain reaction (RT-PCR). Results of IC50 values and the ratios of gene expression were analyzed by linear regression to predict their relationship. RESULTS: Among five CCA cell lines, KKU-M055 was the most sensitive cell line towards all chemotherapeutic drugs investigated, particularly taxane derivatives with IC50 values of 0.02-3 nmol/L, whereas KKU-100 was apparently the least sensitive cell line. When compared to other chemotherapeutic agents, doxorubicin and pirarubicin showed the lowest IC50 values (<5 μmol/L) in all five CCA cell lines. Results from RT-PCR showed that TS, MRP1, MRP3 and GSTP1 were highly expressed in these five CCA cell lines while DPD and MRP2 were only moderately expressed. It should be noted that MDR1 expression was detected only in KKU-OCA17 cell lines. A strong correlation was only found between the level of MRP3 expression and the IC50 values of etoposide, doxorubicin and pirarubicin (r = 0.86-0.98, ,P<0.05). CONCLUSION: Sensitivity to chemotherapeutic agents is not associated with the histological type of CCA. Choosing of the appropriate chemotherapeutic regimen for the treatment of CCA requires knowledge of drug

  1. Regional N2O fluxes in Amazonia derived from aircraft vertical profiles

    Directory of Open Access Journals (Sweden)

    P. Tans

    2009-08-01

    Full Text Available Nitrous oxide (N2O is the third most important anthropogenic greenhouse gas. Globally, the main sources of N2O are nitrification and denitrification in soils. About two thirds of the soil emissions occur in the tropics and approximately 20% originate in wet rainforest ecosystems, like the Amazon forest. The work presented here involves aircraft vertical profiles of N2O from the surface to 4 km over two sites in the Eastern and Central Amazon: Tapajós National Forest (SAN and Cuieiras Biologic Reserve (MAN, and the estimation of N2O fluxes for regions upwind of these sites. To our knowledge, these regional scale N2O measurements in Amazonia are unique and represent a new approach to looking regional scale emissions. The fluxes upwind of MAN exhibited little seasonality, and the annual mean was 2.1±1.0 mg N2O m−2 day−1, higher than that for fluxes upwind of SAN, which averaged 1.5±1.6 mg N2O m−2 day−1. The higher rainfall around the MAN site could explain the higher N2O emissions. For fluxes from the coast to SAN seasonality is present for all years, with high fluxes in the months of March through May, and in November through December. The first peak of N2O flux is strongly associated with the wet season. The second peak of high N2O flux recorded at SAN occurs during the dry season and can not be easily explained. However, about half of the dry season profiles exhibit significant correlations with CO, indicating a larger than expected source of N2O from biomass burning. The average CO:N2O ratio for all profiles sampled during the dry season is 94±77 mol CO:mol N2O and suggests a larger biomass burning contribution to the global N2O budget than previously reported.

  2. Evolution of the polymorphism at molecular markers in QTL and non-QTL regions in selected chicken lines

    NARCIS (Netherlands)

    Loywyck, V.; Bed'hom, B.; Pinard-van der Laan, M.H.; Pitel, F.; Verrier, E.; Bijma, P.

    2008-01-01

    We investigated the joint evolution of neutral and selected genomic regions in three chicken lines selected for immune response and in one control line. We compared the evolution of polymorphism of 21 supposedly neutral microsatellite markers versus 30 microsatellite markers located in seven quantit

  3. Hodgkin Lymphoma Cell Lines Are Characterized by a Specific miRNA Expression Profile

    NARCIS (Netherlands)

    Gibcus, Johan H.; Tan, Lu Ping; Harms, Geert; Schakel, Rikst Nynke; de Jong, Debora; Blokzijl, T.; Moller, Peter; Poppema, Sibrand; Kroesen, Bart-Jan; van den Berg, Anke

    Hodgkin lymphoma (HL) is derived from preapoptotic germinal center B cells, although a general loss of B cell phenotype is noted. Using quantitative reverse transcription-polymerase chain reaction and miRNA microarray, we determined the microRNA (miRNA) profile of HL and compared this with the

  4. Neonatal Cytokine Profile in the Airway Mucosal Lining Fluid Is Skewed by Maternal Atopy

    DEFF Research Database (Denmark)

    Folsgaard, Nilofar V.; Chawes, Bo L.; Rasmussen, Morten A.;

    2012-01-01

    on the cytokines and chemokines in the upper airway mucosal lining fluid of healthy neonates. Objectives: To study parental atopic imprinting on the cytokines and chemokines in the upper airway mucosal lining fluid of healthy neonates. Methods: Eighteen cytokines and chemokines were quantified in nasal mucosal...... lining fluid in 309 neonates from the novel unselected Copenhagen Prospective Study on Asthma in Childhood (COPSAC) birth cohort. Measurements and Main Results: Maternal, but not paternal, atopic status (asthma, hay fever, or eczema with or without sensitization) was associated with general down......-regulation of all 18 mediators assessed by principal component analysis (overall P = 0.015). Conclusions: Maternal atopy, but not paternal atopy, showed a strong linkage with a suppressed mucosal cytokine and chemokine signature in asymptomatic neonates, suggesting imprinting by the maternal milieu in utero...

  5. Vortex line density in counterflowing He II with laminar and turbulent normal fluid velocity profiles

    CERN Document Server

    Baggaley, A W

    2013-01-01

    Superfluid helium is an intimate mixture of a viscous normal fluid, with continuous vorticity, and an inviscid superfluid, where vorticity is constrained to thin, stable topological defects. One mechanism to generate turbulence in this system is through the application of a heat flux, so called thermal counterflow. Of particular interest is how turbulence in the superfluid responds to both a laminar and turbulent normal fluid in the presence of walls. We model superfluid vortex lines as reconnecting space curves with fixed circulation, and consider both laminar (Poiseuille) and turbulent normal fluid flows in a channel configuration. Using high resolution numerical simulations we show that turbulence in the normal fluid sustains a notably higher vortex line density than a laminar flow with the same mean flow rate. We exam Vinen's relation, $\\sqrt{L}=\\gamma v_{ns}$, between the steady state vortex line density $L$ and the counterflow velocity $v_{ns}$. Our results support the hypothesis that transition to turb...

  6. Stacking Spectra in Protoplanetary Disks: Detecting Intensity Profiles from Hidden Molecular Lines in HD 163296

    Science.gov (United States)

    Yen, Hsi-Wei; Koch, Patrick M.; Liu, Hauyu Baobab; Puspitaningrum, Evaria; Hirano, Naomi; Lee, Chin-Fei; Takakuwa, Shigehisa

    2016-12-01

    We introduce a new stacking method in Keplerian disks that (1) enhances signal-to-noise ratios (S/Ns) of detected molecular lines and (2) makes visible otherwise-undetectable weak lines. Our technique takes advantage of the Keplerian rotational velocity pattern. It aligns spectra according to their different centroid velocities at their different positions in a disk and stacks them. After aligning, the signals are accumulated in a narrower velocity range as compared to the original line width without alignment. Moreover, originally correlated noise becomes decorrelated. Stacked and aligned spectra thus have a higher S/N. We apply our method to Atacama Large Millimeter/Submillimeter Array (ALMA) archival data of DCN (3-2), DCO+ (3-2), N2D+ (3-2), and H2CO (3{}{0,3}-2{}{0,2}), (3{}{2,2}-2{}{2,1}), and (3{}{2,1}-2{}{2,0}) in the protoplanetary disk around HD 163296. As a result, (1) the S/Ns of the originally detected DCN (3-2), DCO+ (3-2), H2CO (3{}{0,3}-2{}{0,2}), and N2D+ (3-2) lines are boosted by a factor of ≳4-5 at their spectral peaks, implying one order of magnitude shorter integration times to reach the original S/N; and (2) the previously undetectable spectra of the H2CO (3{}{2,2}-2{}{2,1}) and (3{}{2,1}-2{}{2,0}) lines are materialized at more than 3σ. These dramatically enhanced S/Ns allow us to measure intensity distributions in all lines with high significance. The principle of our method can be applied not only to Keplerian disks but also to any systems with ordered kinematic patterns.

  7. Regional Assessment of soil organic matter profile distribution in the boreal forest ecosystems of Russia

    Science.gov (United States)

    Meshalkina, Joulia; Belousova, Nataliya; Vasenev, Ivan

    2015-04-01

    Boreal forest ecosystems play one of the key roles in the Global Change challenges responses. The soil carbon stocks are principal regulators of their environmental functions. Boreal forest soil cover is characterized by mutually increased spatial variability in soil organic matter content (SOMC) that one need to take into attention in its current and future environmental functions state assessment including the potential of regional soil organic matter stocks changes due to Global Change and inverse ones. Knowledge of the regional regularities in SOMC profile vertical distribution allows improving their soil environmental functions prediction land quality evaluation. More than 900 profiles of SOMC distribution were studied using the database Boreal that contains data on Russian boreal soils developed in drained conditions on loamy soil forming rocks. These soil profiles belong to seven main types of forest soils of Russian classification and six major regions of Russia. The predomination of accumulation profile type was observed for all cases. Thus the vertical distribution of OMC in the profiles of boreal soils can be described as follow: the layer of maximum OMC is replaced by the layer of dramatic OMC reduction; then the layer of minimal OMC extends up to 2.5 m. The layer of maximal OMC accumulation has the low depth of 5-15 cm. It carried out in different genetic horizons: A1, A1A2, A2, B, AB; sometimes it captures the A2B horizon or the upper part of the illuvial horizon. The OMC in this layer increases from the northern taiga to the southern taiga and from the European part of Russia to Siberia. The second layer is characterized by its depth and by the gradient of OMC decreasing. A great variety of the both parameters is observed. The layer of the sharp OMC fall most often fits with the eluvial horizons A2 or А2В or even the upper part of the Вt (textural) or Bm (metamorphic) horizons. The layer of permanently small OMC may begin in any genetic horizon

  8. PROFILES AND PREFERENCES OF ON-LINE MILLENIAL SHOPPERS IN BULGARIA

    OpenAIRE

    Loubeau, Patricia R.; Robert Jantzen; Elitsa Alexander

    2014-01-01

    This research seeks to develop a better understanding of the factors affecting on-line purchasing behavior among Generation Y (Gen Y) consumers in Bulgaria. Also called millenials and born between the mid-1970s and late 1990s, this generation is especially active on-line and will be a dominant influence shaping e-commerce. An empirical study was conducted based on a written survey of a sample consisting of 367 high school and university students in Bulgaria. The most important reason why Bulg...

  9. Regional estimates of glacier mass change from MODIS-derived equilibrium line altitudes

    Directory of Open Access Journals (Sweden)

    J. M. Shea

    2012-09-01

    Full Text Available We describe an automated method to extract regional snowline elevations and annual equilibrium line altitudes (ELAs from daily MODIS imagery (MOD02QKM on large glaciers and icefields in western North America. Regional MODIS-derived ELAs correlate significantly with observed net mass balance at six index glacier mass balance sites. Historical mass balance gradients were combined with MODIS-derived ELAs to estimate annual mass change at the Columbia, Lillooet, and Sittakanay icefields in British Columbia, Canada. Our approach yields estimates of mass change that are within 30% of traditional geodetic approaches over decadal time-scales, and reveals continued mass loss of glaciers in western North America. Between 2000 and 2009, mean annual rates of surface elevation change for the Columbia, Lillooet, and Sittakanay icefields are estimated to be −0.29 ± 0.15 m a−1, −0.57 ± 0.10 m a−1, and −0.90 ± 0.09 m a−1, respectively. This study provides a complementary approach to the development of regional estimates of glacier mass change, which are critical for studies of glacier contributions to both streamflow and global sea-level rise.

  10. Study of superdeformed state of nuclei in $Z=70-80$ drip-line region

    CERN Document Server

    Mahapatro, S; Kumar, Bharat; Patra, S K

    2015-01-01

    We study binding energy, root- mean square radius, quadrapole deformation parameter, two-neutron separation energy and single particle energy levels for various isotopes of Ytterbium (Yb), Hafnium(Hf), Tungsten(W), Osmium(Os), Platinum(Pt) and Mercury(Hg) in $Z = 70 - 80$ drip-line region starting from $N =80$ to $N=170$ within the formalism of relativistic mean field (RMF) theory. We compared our results with Finite Range Droplet Model(FRDM) and experimental data and found that the calculated results are in good agreement. The nuclei $^{168}$Yb,$^{172}$Hf, $^{176}$W, $^{184}$Os, $^{188}$Pt, $^{196}$Hg are found to be most stable isotope in the respective series in the neutron-deficient region. We also observe that there is a shape transition at about $A=190$ in $Z=70-80$ region. The shape changes from oblate to highly prolate shape in their intrinsic ground state. We have also studied probable decay mechanisms of these elements.

  11. The origin of the Narrow Line Region of Mrk 3 an overpressured jet cocoon

    CERN Document Server

    Capetti, A; Macchetto, F D; Marconi, A; Winge, C

    1999-01-01

    We have obtained HST FOC long-slit optical spectroscopy of the Narrow Line Region of the Seyfert 2 galaxy Mrk 3. In the region cospatial with the radio-jet the velocity field is highly perturbed and shows two velocity systems separated by as much as 1700 km/s. We interpret this to be the consequence of the rapid expansion of a cocoon of hot gas, shocked and heated by the radio-emitting outflow, which compresses and accelerates the ambient gas. The NLR itself is essentially a cylindrical shell expanding supersonically. From the size and velocity of the expanding region, we derive an upper limit to the radio-source age, ~ 2 E42 erg/s required to inflate the cocoon and estimate that the jet minimum advance speed is 3 E-3 pc per year. The total kinetic energy of the high velocity NLR gas can be estimated as ~6 E54 erg, comparable to the total energy carried by the jet over its lifetime and this quantitatively supports the idea that the NLR gas is accelerated by the jet. If the advance speed of Mrk 3 is representa...

  12. Measurements of Non-thermal Line Widths in Solar Active Regions

    Science.gov (United States)

    Brooks, David H.; Warren, Harry P.

    2016-03-01

    Spectral line widths are often observed to be larger than can be accounted for by thermal and instrumental broadening alone. This excess broadening is a key observational constraint for both nanoflare and wave dissipation models of coronal heating. Here we present a survey of non-thermal velocities measured in the high temperature loops (1-4 MK) often found in the cores of solar active regions. This survey of Hinode Extreme Ultraviolet Imaging Spectrometer (EIS) observations covers 15 non-flaring active regions that span a wide range of solar conditions. We find relatively small non-thermal velocities, with a mean value of 17.6 ± 5.3 km s-1, and no significant trend with temperature or active region magnetic flux. These measurements appear to be inconsistent with those expected from reconnection jets in the corona, chromospheric evaporation induced by coronal nanoflares, and Alfvén wave turbulence models. Furthermore, because the observed non-thermal widths are generally small, such measurements are difficult and susceptible to systematic effects.

  13. Measurements of Non-Thermal Line Widths in Solar Active Regions

    CERN Document Server

    Brooks, David H

    2015-01-01

    Spectral line widths are often observed to be larger than can be accounted for by thermal and instrumental broadening alone. This excess broadening is a key observational constraint for both nanoflare and wave dissipation models of coronal heating. Here we present a survey of non-thermal velocities measured in the high temperature loops (1--5MK) often found in the cores of solar active regions. This survey of $\\textit{Hinode}$ Extreme Ultraviolet Imaging Spectrometer (EIS) observations covers 15 non-flaring active regions that span a wide range of solar conditions. We find relatively small non-thermal velocities, with a mean value of 17km s$^{-1}$, and no significant trend with temperature or active region magnetic flux. These measurements appear to be inconsistent with those expected from reconnection jets in the corona, chromospheric evaporation induced by coronal nanoflares, and Alfv\\'en wave turbulence models. Furthermore, because the observed non-thermal widths are generally small their measurements are ...

  14. MEASUREMENTS OF NON-THERMAL LINE WIDTHS IN SOLAR ACTIVE REGIONS

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, David H. [College of Science, George Mason University, 4400 University Drive, Fairfax, VA 22030 (United States); Warren, Harry P. [Space Science Division, Naval Research Laboratory, Washington, DC 20375 (United States)

    2016-03-20

    Spectral line widths are often observed to be larger than can be accounted for by thermal and instrumental broadening alone. This excess broadening is a key observational constraint for both nanoflare and wave dissipation models of coronal heating. Here we present a survey of non-thermal velocities measured in the high temperature loops (1–4 MK) often found in the cores of solar active regions. This survey of Hinode Extreme Ultraviolet Imaging Spectrometer (EIS) observations covers 15 non-flaring active regions that span a wide range of solar conditions. We find relatively small non-thermal velocities, with a mean value of 17.6 ± 5.3 km s{sup −1}, and no significant trend with temperature or active region magnetic flux. These measurements appear to be inconsistent with those expected from reconnection jets in the corona, chromospheric evaporation induced by coronal nanoflares, and Alfvén wave turbulence models. Furthermore, because the observed non-thermal widths are generally small, such measurements are difficult and susceptible to systematic effects.

  15. Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR

    Directory of Open Access Journals (Sweden)

    Kawaguchi Makoto

    2010-01-01

    Full Text Available Abstract Background Lung cancers are the most common type of human malignancy and are intractable. Lung cancers are generally classified into four histopathological subtypes: adenocarcinoma (AD, squamous cell carcinoma (SQ, large cell carcinoma (LC, and small cell carcinoma (SC. Molecular biological characterization of these subtypes has been performed mainly using DNA microarrays. In this study, we compared the gene expression profiles of these four subtypes using twelve human lung cancer cell lines and the more reliable quantitative real-time PCR (qPCR. Results We selected 100 genes from public DNA microarray data and examined them by DNA microarray analysis in eight test cell lines (A549, ABC-1, EBC-1, LK-2, LU65, LU99, STC 1, RERF-LC-MA and a normal control lung cell line (MRC-9. From this, we extracted 19 candidate genes. We quantified the expression of the 19 genes and a housekeeping gene, GAPDH, with qPCR, using the same eight cell lines plus four additional validation lung cancer cell lines (RERF-LC-MS, LC-1/sq, 86-2, and MS-1-L. Finally, we characterized the four subtypes of lung cancer cell lines using principal component analysis (PCA of gene expression profiling for 12 of the 19 genes (AMY2A, CDH1, FOXG1, IGSF3, ISL1, MALL, PLAU, RAB25, S100P, SLCO4A1, STMN1, and TGM2. The combined PCA and gene pathway analyses suggested that these genes were related to cell adhesion, growth, and invasion. S100P in AD cells and CDH1 in AD and SQ cells were identified as candidate markers of these lung cancer subtypes based on their upregulation and the results of PCA analysis. Immunohistochemistry for S100P and RAB25 was closely correlated to gene expression. Conclusions These results show that the four subtypes, represented by 12 lung cancer cell lines, were well characterized using qPCR and PCA for the 12 genes examined. Certain genes, in particular S100P and CDH1, may be especially important for distinguishing the different subtypes. Our results

  16. Measurement of storage time, estimation of ion number and study of absorption line profile in a Paul trap

    Indian Academy of Sciences (India)

    Soumen Bhattacharyya; Anita Gupta; S G Nakhate; Pushpa M Rao

    2006-12-01

    Europium (Eu+) ions were confined in a Paul trap and detected by non-destructive method. Storage time of Eu+ ions achieved in vacuum was improved by orders of magnitude employing buffer gas cooling. The experimentally detected signal was fitted to the ion response signal and the total number of ions trapped was estimated. It is found that the peak signal amplitude as well as the product of FWHM and the peak signal amplitude is proportional to the total number of trapped ions. The trapped ion secular frequency was swept at different rates and its effect on the absorption line profile was studied both experimentally and theoretically.

  17. A Revised Broad-line Region Radius and Black Hole Mass for the Narrow-line Seyfert 1 NGC 4051

    DEFF Research Database (Denmark)

    Denney, K. D.; Watson, L. C.; Peterson, B. M.

    2009-01-01

    ) radius and the optical continuum luminosity—the R BLR-L relationship. Our new measurements of the lag time between variations in the continuum and Hß emission line made from spectroscopic monitoring of NGC 4051 lead to a measured BLR radius of R BLR = 1.87+0.54 -0.50 light days and black hole mass of M...

  18. DNA Methylation Profiles of Protease Nexin 1 (SERPINE2) Gene in Human Cell Lines

    Institute of Scientific and Technical Information of China (English)

    Shan Gao; Peter A. Andreasen

    2011-01-01

    Objective: To investigated whether epigenetic mechanisms contribute to the variable expression of variable protease nexin1(PN-1) encoded by the SERPINE2 gene in different cell types. Methods: Working with 5 human cell lines, we determined the CpG methylation status within two CpG islands in the SERPINE2 gene by bisulphate sequencing and the PN-1 mRNA level by Q-RT PCR. Results: A CpG island spanning the transcription initiation site showed little methylation in 3 of the cell lines and substantial methylation in 2 of the cell lines. A CpG island covering the translation starting site showed full methylation in all investigated cell lines. Methylation within the CpG island was not randomly distributed, but showed accumulation at specific sites. However, we were not able to distinguish any patterns which related the methylation frequency to the gene expression level. Inhibition of CpG methylation with 5-aza-2′-deoxycytidine led to a several fold increase in PN-1 mRNA levels, but based on the results on CpG methylation in the CpG island spanning the transcript, the effect is most likely indirect. Conclusion: We have carefully mapped the CpG methylation pattern in two CpG islands in the 5′ part of the SERPINE2 gene without finding any obvious inverse correlation between methylation frequency and expression level.

  19. Stacking Spectra in Protoplanetary Disks: Detecting Intensity Profiles from Hidden Molecular Lines in HD 163296

    CERN Document Server

    Yen, Hsi-Wei; Liu, Hauyu Baobab; Puspitaningrum, Evaria; Hirano, Naomi; Lee, Chin-Fei; Takakuwa, Shigehisa

    2016-01-01

    We introduce a new stacking method in Keplerian disks that (1) enhances signal-to-noise ratios (S/N) of detected molecular lines and (2) that makes visible otherwise undetectable weak lines. Our technique takes advantage of the Keplerian rotational velocity pattern. It aligns spectra according to their different centroid velocities at their different positions in a disk and stacks them. After aligning, the signals are accumulated in a narrower velocity range as compared to the original line width without alignment. Moreover, originally correlated noise becomes de-correlated. Stacked and aligned spectra, thus, have a higher S/N. We apply our method to ALMA archival data of DCN (3-2), DCO+ (3-2), N2D+ (3-2), and H2CO (3_0,3-2_0,2), (3_2,2-2_2,1), and (3_2,1-2_2,0) in the protoplanetary disk around HD 163296. As a result, (1) the S/N of the originally detected DCN (3-2), DCO+ (3-2), and H2CO (3_0,3-2_0,2) and N2D+ (3-2) lines are boosted by a factor of >4-5 at their spectral peaks, implying one order of magnitud...

  20. Effect of D-allose on prostate cancer cell lines: phospholipid profiling by nanoflow liquid chromatography-tandem mass spectrometry.

    Science.gov (United States)

    Jeong, Rae Ung; Lim, Sangsoo; Kim, Myoung Ok; Moon, Myeong Hee

    2011-08-01

    D-Allose, a rare, naturally occurring monosaccharide, is known to exert anti-proliferative effects on cancer cells. The effects of D-allose on the cellular membranes of hormone-refractory prostate cancer cell line (DU145), hormone-sensitive prostate cancer cell line (LNCaP), and normal prostate epithelial cells (PrEC) were studied at the molecular level by phospholipid (PL) profiling using a shotgun lipidomic method. The molecular structures of 85 PL species including 23 phosphatidylcholines, 12 phosphatidylethanolamines (PEs), 11 phosphatidylserines (PSs), 16 phosphatidylinositols, 9 phosphatidic acids (PAs), and 14 phosphatidylglycerols (PGs) were identified by data-dependent collision-induced dissociation of nanoflow liquid chromatography-tandem mass spectrometry, and the PL amounts were quantified. The addition of D-allose to prostate cancer cell lines during their growth phases had negligible or decreased effects on the relative regulation of PL species, but several new PS molecules (two for DU145 and three for LNCaP) emerged. In contrast, experiments on the PrEC cell line revealed that some high abundant species (14:0/14:0-PE, 16:2/16:0-PG, and 20:6/18:1-PA) showed significant increases in concentration. These findings support a mechanism for the anti-proliferative effect of D-allose on prostate cancer cell lines that involves the induction of programmed cell death since PS molecules are known to induce apoptosis. Principal component analysis was carried out to examine differences in PL distributions among the three cell lines promoted by D-allose.

  1. Differential Effects of Intrauterine Growth Restriction on the Regional Neurochemical Profile of the Developing Rat Brain.

    Science.gov (United States)

    Maliszewski-Hall, Anne M; Alexander, Michelle; Tkáč, Ivan; Öz, Gülin; Rao, Raghavendra

    2017-01-01

    Intrauterine growth restricted (IUGR) infants are at increased risk for neurodevelopmental deficits that suggest the hippocampus and cerebral cortex may be particularly vulnerable. Evaluate regional neurochemical profiles in IUGR and normally grown (NG) 7-day old rat pups using in vivo (1)H magnetic resonance (MR) spectroscopy at 9.4 T. IUGR was induced via bilateral uterine artery ligation at gestational day 19 in pregnant Sprague-Dawley dams. MR spectra were obtained from the cerebral cortex, hippocampus and striatum at P7 in IUGR (N = 12) and NG (N = 13) rats. In the cortex, IUGR resulted in lower concentrations of phosphocreatine, glutathione, taurine, total choline, total creatine (P regions. Persistent neurochemical changes may lead to cortex-based long-term neurodevelopmental deficits in human IUGR infants.

  2. A coronagraphic absorbing cloud reveals the narrow-line region and extended Lyman-$\\alpha$ emission of QSO J0823+0529

    CERN Document Server

    Fathivavsari, Hassan; Noterdaeme, Pasquier; Pâris, Isabelle; Finley, Hayley; López, Sebastian; Srianand, Raghunathan; Sánchez, Paula

    2015-01-01

    We report long-slit spectroscopic observations of the quasar SDSS J082303.22+052907.6 ($z_{\\rm CIV}$$\\sim$3.1875), whose Broad Line Region (BLR) is partly eclipsed by a strong damped Lyman-$\\alpha$ (DLA; log$N$(HI)=21.7) cloud. This allows us to study the Narrow Line Region (NLR) of the quasar and the Lyman-$\\alpha$ emission from the host galaxy. Using CLOUDY models that explain the presence of strong NV and PV absorption together with the detection of SiII$^*$ and OI$^{**}$ absorption in the DLA, we show that the density and the distance of the cloud to the quasar are in the ranges 180 $$ $r_0$ $>$230 pc, respectively. Sizes of the neutral($\\sim$2-9pc) and highly ionized phases ($\\sim$3-80pc) are consistent with the partial coverage of the CIV broad line region by the CIV absorption from the DLA (covering factor of $\\sim$0.85). We show that the residuals are consistent with emission from the NLR with CIV/Lyman-$\\alpha$ ratios varying from 0 to 0.29 through the profile. Remarkably, we detect extended Lyman-$\\...

  3. Carbon Monoxide Poisoning in the Region of Fez-Boulemane, Morocco: Epidemiological Profile and Risk Factors (2009-2012

    Directory of Open Access Journals (Sweden)

    Awatef Tahouri

    2013-12-01

    How to cite this article: Tahouri A, Lyoussi B, Achour S. Carbon Monoxide Poisoning in the Region of Fez-Boulemane, Morocco: Epidemiological Profile and Risk Factors (2009-2012. Asia Pac J Med Toxicol 2013;2:131-5.

  4. Water vapor absorption line intensities in the 1900-6600 cm{sup -1} region

    Energy Technology Data Exchange (ETDEWEB)

    Mikhailenko, S.N. [Laboratory of Theoretical Spectroscopy, Institute of Atmospheric Optics, Russian Academy of Sciences, 1, Akademicheskaya Avenue, 634055 Tomsk (Russian Federation)], E-mail: semen@lts.iao.ru; Keppler Albert, K.A. [Physikalisch-Chemisches Institut, Justus-Liebig-Universitaet Giessen, Heinrich-Buff-Ring 58, D-35392 Giessen (Germany); Physical Chemistry, ETH Zuerich, Hoenggerberg, CH-8093 Zuerich (Switzerland); Mellau, G.; Klee, S. [Physikalisch-Chemisches Institut, Justus-Liebig-Universitaet Giessen, Heinrich-Buff-Ring 58, D-35392 Giessen (Germany); Winnewisser, B.P.; Winnewisser, M. [Physikalisch-Chemisches Institut, Justus-Liebig-Universitaet Giessen, Heinrich-Buff-Ring 58, D-35392 Giessen (Germany); Department of Physics, Ohio State University, Columbus, OH 43210 (United States); Tyuterev, Vl.G. [Groupe de Spectrometrie Moleculaire et Atmospherique, UMR CNRS 6089, Faculte des Sciences, Universite de Reims, Moulin de la Housse, BP 1039, 51687 Reims Cedex 2 (France)

    2008-11-15

    Water vapor infrared spectra have been measured using the Bruker IFS 120 HR Fourier transform spectrometer at the Physikalisch-Chemisches Institut of the Justus-Liebig-Universitaet Giessen. Spectra were recorded at pressure-broadening-limited resolution and at room temperature in the range of 1900-6600 cm{sup -1}. The use of fully evacuated transfer optics and a White-type multireflection cell made it possible to obtain pressurexpathlength products up to 31.27 mbarx288.5 m. These spectra have previously been used to determine experimental values of rovibrational line positions and upper energy levels of the 2{nu}{sub 2}, {nu}{sub 1}, and {nu}{sub 3} bands [Mikhailenko SN, Tyuterev VlG, Keppler KA, Winnewisser BP, Winnewisser M, Mellau G, et. al. The 2{nu}{sub 2} band of water: analysis of new FTS measurements and high-K{sub a} transitions and energy levels. J Mol Spectrosc 1997;184: 330-49] and of the 3{nu}{sub 2}, {nu}{sub 1}+{nu}{sub 2}, and {nu}{sub 2}+{nu}{sub 3} bands [Mikhailenko SN, Tyuterev VlG, Starikov VI, Albert KK, Winnewisser BP, Winnewisser M, et al. Water spectra in the region 4200-6250 cm{sup -1}, extended analysis of {nu}{sub 1}+{nu}{sub 2}, {nu}{sub 2}+{nu}{sub 3}, and 3{nu}{sub 2} bands and confirmation of highly excited states from flame spectra and from atmospheric long-path observations. J. Mol. Spectrosc. 2002; 213: 91-121]. This work presents the intensities of 3769 lines for the weak and medium transitions in the spectral range indicated. These data provide an independent source of experimental information which is complementary to intensity data available in the literature and can thus help to evaluate experimental errors and the reliability of these spectral line parameters.

  5. Absolute intensities of CO(2) lines in the 3140-3410-cm(-1) spectral region.

    Science.gov (United States)

    Benner, D C; Devi, V M; Rinsland, C P; Ferry-Leeper, P S

    1988-04-15

    Absolute intensities for 430 transitions belonging to eleven rotation-vibration bands of (12)C(16)O(2),(13)C(16)O(2) and(16)O(12)C(18)O in the 3140-3410-cm(-1) spectral region have been determined by analyzing spectra recorded at 0.01-cm(-1) resolution with the Fourier transform spectrometer in the McMath solar telescope complex at the National Solar Observatory on Kitt Peak. The data were recorded at room temperature and low pressures (Coriolis effect is large and the Q-branch line intensities were not determinate either because they were severely blended or absent from the spectra. Comparisons are made between the results obtained in this study and other published values.

  6. An Extended Look at the Narrow-Line Region of the Seyfert 2 Galaxy Mrk 573

    Science.gov (United States)

    Machuca, Camilo; Fischer, Travis C.; Crenshaw, D. Michael

    2017-01-01

    Active galactic nuclei (AGN) are supermassive black holes found in the centers of galaxies which accrete matter from their surroundings and subsequently produce AGN feedback in the form of ionized and molecular gas outflows. These outflows are largely contained within the Narrow-Line Region (NLR), a low density sector that extends froms tens to thousands of parsecs away from the nucleus. In order to clarify the relationship between the AGN and its host galaxy at these various distances, we present this study on Mrk 573, a Seyfert 2 AGN, based on long-slit spectroscopy from the Dual Imaging Spectrograph (DIS) on the ARC 3.5-meter telescope at Apache Point Observatory. We find that the dominant ionization mechanism of the gas up to a radius of 2 kpc can be attributed to the AGN and that the ionized gas kinematics are dominated by galactic rotation at distances larger than 750 pc.

  7. Are the Narrow Line Regions in Active Galaxies Dusty and Radiation Pressure Dominated?

    CERN Document Server

    Dopita, M A; Sutherland, R S; Binette, L; Cecil, G N

    2002-01-01

    The remarkable similarity between emission spectra of narrow line regions (NLR) in Seyfert Galaxies has long presented a mystery. In photoionization models, this similarity implies that the ionization parameter is nearly always the same, about U ~ 0.01. Here we present dusty, radiation-pressure dominated photoionization models that can provide natural physical insight into this problem. In these models, dust and the radiation pressure acting on it provide the controlling factor in moderating the density, excitation and surface brightness of photoionized NLR structures. Additionally, photoelectric heating by the dust is important in determining the temperature structure of the models. These models can also explain the coexistence of the low-, intermediate- and coronal ionization zones within a single self-consistent physical structure. The radiation pressure acting on dust may also be capable of driving the fast (~3000 km/s) outflows such as are seen in the HST observations of NGC 1068.

  8. Magnetically elevated accretion disks in active galactic nuclei: broad emission line regions and associated star formation

    CERN Document Server

    Begelman, Mitchell C

    2016-01-01

    We propose that the accretion disks fueling active galactic nuclei are supported vertically against gravity by a strong toroidal ($\\phi-$direction) magnetic field that develops naturally as the result of an accretion disk dynamo. The magnetic pressure elevates most of the gas carrying the accretion flow at $R$ to large heights $z > 0.1 R$ and low densities, while leaving a thin dense layer containing most of the mass --- but contributing very little accretion --- around the equator. We show that such a disk model leads naturally to the formation of a broad emission line region through thermal instability. Extrapolating to larger radii, we demonstrate that local gravitational instability and associated star formation are strongly suppressed compared to standard disk models for AGN, although star formation in the equatorial zone is predicted for sufficiently high mass supply rates. This new class of accretion disk models thus appears capable of resolving two longstanding puzzles in the theory of AGN fueling: th...

  9. Reconstructing the velocity dispersion profiles from the line-of-sight kinematic data in disc galaxies

    Science.gov (United States)

    Marchuk, A. A.; Sotnikova, N. Y.

    2017-03-01

    We present a modification of the method for reconstructing the stellar velocity ellipsoid (SVE) in disc galaxies. Our version does not need any parametrization of the velocity dispersion profiles and uses only one assumption that the ratio σz/σR remains constant along the profile or along several pieces of the profile. The method was tested on two galaxies from the sample of other authors and for the first time applied to three lenticular galaxies NGC 1167, NGC 3245 and NGC 4150, as well as to one Sab galaxy NGC 338. We found that for galaxies with a high inclination (i >55° - 60°) it is difficult or rather impossible to extract the information about SVE, while for galaxies at an intermediate inclination the procedure of extracting is successful. For NGC 1167 we managed to reconstruct SVE, provided that the value of σz/σR is piecewise constant. We found σz/σR = 0.7 for the inner parts of the disc and σz/σR = 0.3 for the outskirts. We also obtained a rigid constraint on the value of the radial velocity dispersion σR for highly inclined galaxies, and tested the result using the asymmetric-drift equation, provided that the gas rotation curve is available.

  10. Gene expression profiles in rat brain disclose CNS signature genes and regional patterns of functional specialisation

    Directory of Open Access Journals (Sweden)

    Breilid Harald

    2007-04-01

    distribution within the CNS, respectively. The existence of shared specialised neuronal activities in CNS is interesting in a context of potential functional redundancy, and future studies should further explore the overall characteristics of CNS-specific versus region-specific gene profiles in the brain.

  11. The Role of Radiation Pressure in the Narrow Line Regions of Seyfert Host Galaxies

    CERN Document Server

    Davies, Rebecca L; Kewley, Lisa J; Groves, Brent; Sutherland, Ralph; Hampton, Elise J; Shastri, Prajval; Kharb, Preeti; Bhatt, Harish; Scharwächter, Julia; Jin, Chichuan; Banfield, Julie; Zaw, Ingyin; James, Bethan; Juneau, Stéphanie; Srivastava, Shweta

    2016-01-01

    We investigate the relative significance of radiation pressure and gas pressure in the extended narrow line regions (ENLRs) of four Seyfert galaxies from the integral field Siding Spring Southern Seyfert Spectroscopic Snapshot Survey (S7). We demonstrate that there exist two distinct types of starburst-AGN mixing curves on standard emission line diagnostic diagrams which reflect the balance between gas pressure and radiation pressure in the ENLR. In two of the galaxies the ENLR is radiation pressure dominated throughout and the ionization parameter remains constant (log U ~ 0). In the other two galaxies radiation pressure is initially important, but gas pressure becomes dominant as the ionization parameter in the ENLR decreases from log U ~ 0 to -3.4 <= log U <= -3.2. Where radiation pressure is dominant, the AGN regulates the density of the interstellar medium on kpc scales and may therefore have a direct impact on star formation activity and/or the incidence of outflows in the host galaxy to scales fa...

  12. The Role of Radiation Pressure in the Narrow Line Regions of Seyfert Host Galaxies

    Science.gov (United States)

    Davies, Rebecca L.; Dopita, Michael A.; Kewley, Lisa; Groves, Brent; Sutherland, Ralph; Hampton, Elise J.; Shastri, Prajval; Kharb, Preeti; Bhatt, Harish; Scharwächter, Julia; Jin, Chichuan; Banfield, Julie; Zaw, Ingyin; James, Bethan; Juneau, Stéphanie; Srivastava, Shweta

    2016-06-01

    We investigate the relative significance of radiation pressure and gas pressure in the extended narrow line regions (ENLRs) of four Seyfert galaxies from the integral field Siding Spring Southern Seyfert Spectroscopic Snapshot Survey (S7). We demonstrate that there exist two distinct types of starburst-active galactic nucleus (AGN) mixing curves on standard emission line diagnostic diagrams, which reflect the balance between gas pressure and radiation pressure in the ENLR. In two of the galaxies the ENLR is radiation pressure dominated throughout and the ionization parameter remains constant (log U ˜ 0). In the other two galaxies radiation pressure is initially important, but gas pressure becomes dominant as the ionization parameter in the ENLR decreases from log U ˜ 0 to -3.2 ≲ log U ≲ -3.4. Where radiation pressure is dominant, the AGN regulates the density of the interstellar medium on kiloparsec scales and may therefore have a direct impact on star formation activity and/or the incidence of outflows in the host galaxy to scales far beyond the zone of influence of the black hole. We find that both radiation pressure dominated and gas pressure dominated ENLRs are dynamically active with evidence for outflows, indicating that radiation pressure may be an important source of AGN feedback even when it is not dominant over the entire ENLR.

  13. Gamma-ray opacity of the anisotropic stratified broad-line regions in blazars

    CERN Document Server

    Abolmasov, Pavel

    2016-01-01

    The GeV-range spectra of blazars are shaped not only by non-thermal emission processes internal to the relativistic jet but also by external pair-production absorption on the thermal emission of the accretion disc and the broad-line region (BLR). For the first time, we compute here the pair-production opacities in the GeV range produced by a realistic BLR accounting for the radial stratification and radiation anisotropy. Using photoionization modelling with the CLOUDY code, we calculate a series of BLR models of different sizes, geometries, cloud densities, column densities and metallicities. The strongest emission features in the model BLR are Ly$\\alpha$ and HeII Ly$\\alpha$. Contribution of recombination continua is smaller, especially for hydrogen, because Ly continuum is efficiently trapped inside the large optical depth BLR clouds and converted to Lyman emission lines and higher-order recombination continua. The largest effects on the gamma-ray opacity are produced by the BLR geometry and localization of ...

  14. Spatially Resolving the Kinematics of the <100 {\\mu}as Quasar Broad Line Region using Spectroastrometry

    CERN Document Server

    Stern, Jonathan; Pott, Jörg-Uwe

    2015-01-01

    The broad line region (BLR) of luminous active galactic nuclei (AGN) is a prominent observational signature of the accretion flow around supermassive black holes, which can be used to measure their masses (M_BH) over cosmic history. Due to the <100 {\\mu}as angular size of the BLR, current direct constraints on BLR kinematics are limited to those provided by reverberation mapping studies, which are most efficiently carried out on low-luminosity L and low-redshift z AGN. We analyze the possibility to measure the BLR size and study its kinematic structure using spectroastrometry, whereby one measures the spatial position centroid of emission line photons as a function of velocity. We calculate the expected spectroastrometric signal of a rotation-dominated BLR for various assumptions about the ratio of random to rotational motions, and the radial distribution of the BLR gas. We show that for hyper-luminous quasars at z < 2.5, the size of the low-ionization BLR can already be constrained with existing telesc...

  15. 输电线路区域管控线格化管理实践%Line-grid Management Practice for Regional Transmission Line Control

    Institute of Scientific and Technical Information of China (English)

    关利平; 关华平

    2015-01-01

    指出线路保护区内超高树木、违章建筑、施工等因素的影响已成为线路安全运行的重大隐患,通道清理是运行维护难点和重点。提出线路区域管控线格化的工作思路,通过地方人力资源的利用,传递护线责任,建立地(市)、县(区)、乡(镇)三级护线制度;聘请当地有责任心的村民护线,从线路基本运行情况、通道清障和运检管理等方面分析线路区域管理特色;建议充分发挥属地管理的优势,实施分级护线和群众护线制度,确保区域管控线格化管理实用高效。%The safe operation of transmission lines is threatened by many factors, including high trees and unauthorized construction in the protected zone so that channel clearing is the focus for line maintenance. The scheme of line-grid management is put forward for transmission line maintenance. Three-level line protection system (the municipal level, county-level and township-level) is established. Local villagers with strong responsibility are employed to protect transmission lines. Regional management of transmission lines is analysed from the aspects of the basic operation condition, channel clearing and inspection management etc.. It is suggested to promote localized management and three-level line protection system to ensure the efficiency of regional management.

  16. DIFFERENTIAL EFFECTS OF INTRAUTERINE GROWTH RESRICTION ON THE REGIONAL NEUROCHEMICAL PROFILE OF THE DEVELOPING RAT BRAIN

    Science.gov (United States)

    Maliszewski-Hall, Anne M.; Alexander, Michelle; Tkáč, Ivan; Öz, Gülin; Rao, Raghavendra

    2016-01-01

    Background Intrauterine growth restricted (IUGR) infants are at increased risk for neurodevelopmental deficits that suggest the hippocampus and cerebral cortex may be particularly vulnerable. Objective Evaluate regional neurochemical profiles in IUGR and normally grown (NG) 7-day old rat pups using in vivo 1H magnetic resonance (MR) spectroscopy at 9.4T. Methods IUGR was induced via bilateral uterine artery ligation at gestational day 19 in pregnant Sprague Dawley dams. MR spectra were obtained from the cerebral cortex, hippocampus and striatum at P7 in IUGR (N=12) and NG (N=13) rats. Results In the cortex, IUGR resulted in lower concentrations of phosphocreatine, glutathione, taurine, total choline, total creatine (P<0.01) and [glutamate]/[glutamine] ratio (P <0.05). Lower taurine concentrations were observed in the hippocampus (P<0.01) and striatum (P <0.05). Conclusion IUGR differentially affects the neurochemical profile of the P7 rat brain regions. Persistent neurochemical changes may lead to cortex-based long-term neurodevelopmental deficits in human IUGR infants. PMID:25972040

  17. MiRNA Profiles in Lymphoblastoid Cell Lines of Finnish Prostate Cancer Families.

    Directory of Open Access Journals (Sweden)

    Daniel Fischer

    Full Text Available Heritable factors are evidently involved in prostate cancer (PrCa carcinogenesis, but currently, genetic markers are not routinely used in screening or diagnostics of the disease. More precise information is needed for making treatment decisions to distinguish aggressive cases from indolent disease, for which heritable factors could be a useful tool. The genetic makeup of PrCa has only recently begun to be unravelled through large-scale genome-wide association studies (GWAS. The thus far identified Single Nucleotide Polymorphisms (SNPs explain, however, only a fraction of familial clustering. Moreover, the known risk SNPs are not associated with the clinical outcome of the disease, such as aggressive or metastasised disease, and therefore cannot be used to predict the prognosis. Annotating the SNPs with deep clinical data together with miRNA expression profiles can improve the understanding of the underlying mechanisms of different phenotypes of prostate cancer.In this study microRNA (miRNA profiles were studied as potential biomarkers to predict the disease outcome. The study subjects were from Finnish high risk prostate cancer families. To identify potential biomarkers we combined a novel non-parametrical test with an importance measure provided from a Random Forest classifier. This combination delivered a set of nine miRNAs that was able to separate cases from controls. The detected miRNA expression profiles could predict the development of the disease years before the actual PrCa diagnosis or detect the existence of other cancers in the studied individuals. Furthermore, using an expression Quantitative Trait Loci (eQTL analysis, regulatory SNPs for miRNA miR-483-3p that were also directly associated with PrCa were found.Based on our findings, we suggest that blood-based miRNA expression profiling can be used in the diagnosis and maybe even prognosis of the disease. In the future, miRNA profiling could possibly be used in targeted screening

  18. An estimate of the DM profile in the Galactic bulge region

    CERN Document Server

    Iocco, Fabio

    2016-01-01

    We present an analysis of the mass distribution in the region of the Galactic bulge, which leads to constraints on the total amount and distribution of Dark Matter (DM) therein. Our results -based on the dynamical measurement of the BRAVA collaboration- are quantitatively compatible with those of a recent analysis, and generalised to a vaste sample of observationally inferred morphologies of the stellar components in the region of the Galactic bulge. By fitting the inferred DM mass to a generalised NFW profile, we find that cores (index gamma smaller than 0.6) are forbidden only for very light configurations of the bulge, and that cusps (index gamma bigger than 1.2) are allowed, but not necessarily preferred. Interestingly, we find that the results for the bulge region are compatible with those obtained with dynamical methods (based on the rotation curve) applied to outer regions of the Milky Way, for all morphologies adopted. We find that the uncertainty on the shape of the stellar morphology heavily affects...

  19. Profiling flavonoid cytotoxicity in human breast cancer cell lines: determination of structure-function relationships.

    Science.gov (United States)

    Yadegarynia, Sina; Pham, Anh; Ng, Alex; Nguyen, Duong; Lialiutska, Tetiana; Bortolazzo, Anthony; Sivryuk, Valentin; Bremer, Martina; White, J Brandon

    2014-05-01

    Flavonoids have been shown to be cytotoxic to cancer cells. However, the mechanism of cytotoxicity has not been clearly defined. It has previously been reported that HER2/ERBB2, the estrogen receptor, progesterone receptor, and p53 were required for flavonoid induced cytotoxicity in breast cancer cell lines. We have used a panel of breast cancer cell lines, known to contain as well as be deficient in these signaling pathways, to screen fourteen different flavonoids. Comparing the cytotoxicity for all flavonoids allows us to determine if a structure-functional relationship exists between cytotoxicity and flavonoid, and if a particular signaling pathway is required for cytotoxicity. We show that several flavonoids are cytotoxic to all cell lines including primary mammary epithelial cells tested. The cytotoxic flavonoids are also able to inhibit Mitochondrial Outer Membrane Permeability while at the same time stimulate ATP levels whereas the non-cytotoxic flavonoids are not able to do this. We also show that both cytotoxic and non-cytotoxic flavonoids can transverse the cell membrane to enter MDA-MB-231 cells at different levels. Finally, all flavonoids regardless of their cytotoxicity were able to induce some form of cell cycle arrest. We conclude that for flavonoids to be strongly cytotoxic, they must possess the 2,3-double bond in the C-ring and we believe the cytotoxicity occurs through mitochondrial poisoning in both cancer and normal cells.

  20. Genomic profiling in CEPH cell lines distinguishes between the camptothecins and indenoisoquinolines.

    Science.gov (United States)

    Watson, Venita Gresham; Hardison, Nicholas E; Harris, Tyndall; Motsinger-Reif, Alison; McLeod, Howard L

    2011-10-01

    We have attempted to use a familial genetics strategy to study mechanisms of topoisomerase 1 (Top1) inhibition. Investigations have steadily been chipping away at the pathways involved in cellular response following Top1 inhibition for more than 20 years. Our system-wide approach, which phenotypes a collection of genotyped human cell lines for sensitivity to compounds and interrogates all genes and molecular pathways simultaneously. Previously, we characterized the in vitro sensitivity of 15 families of Centre d'Etude Polymorphisme Humain (CEPH) cell lines (n = 142) to 9 camptothecin analogues. Linkage analysis revealed a pattern of 7 quantitative trait loci (QTL) shared by all of the camptothecins. To identify which, if any, QTLs are related to the general mechanism of Top1 inhibition or should be considered camptothecin specific, we characterized the in vitro sensitivity of the same panel of CEPH cell lines to the indenisoquinolones, a structurally distinct class of Top1 inhibitors. Four QTLs on chromosomes 1, 5, 11, and 16 were shared by both the camptothecins and the indenoisoquinolines and are considered associated with the general mechanism of Top1 inhibition. The remaining 3 QTLs (chromosomes 6 and 20) are considered specific to camptothecin-induced cytotoxicity. Finally, 8 QTLs were identified, which were unique to the indenoisoquinolines.

  1. An Abel transform for deriving line-of-sight wind profiles from LEO-LEO infrared laser occultation measurements

    Science.gov (United States)

    Syndergaard, S.; Kirchengast, G.

    2016-03-01

    We have developed a formula for the retrieval of the line-of-sight (l.o.s.) wind speed from future low Earth orbit (LEO) satellite-to-satellite infrared laser occultation measurements. The formula involves an Abelian integral transform akin to the Abel transform widely used for deriving refractive index from bending angle in Global Navigation Satellite System radio occultation measurements. Besides the Abelian integral transform, the formula is derived from a truncated series expansion of the volume absorption coefficient as a function of frequency and includes a simple absorption-line-asymmetry correction term. A first-order formulation (referred to as the standard formula) is complemented by higher-order terms that can be used for high-accuracy computations. Under the assumptions of spherical symmetry and perfect knowledge of spectroscopy, the residual l.o.s. wind error from using the standard formula rather than the high-accuracy formula is assessed to be small compared to that anticipated from measurement errors in a real experiment. Applying the new formula just in standard form to future infrared laser transmission profiles would therefore enable the retrieval of l.o.s. stratospheric wind profiles with an accuracy limited mainly by measurement errors, residual spectroscopic errors, and deviations from spherical symmetry.

  2. Epidemiological profile of suicide in the Santa Catarina Coal Mining Region from 1980 to 2007

    Directory of Open Access Journals (Sweden)

    Carolina H. Portella

    2013-01-01

    Full Text Available BACKGROUND: Suicide is a public health problem worldwide. Estimates have indicated that over 1 million people commit suicide every year all over the world. Brazil has a moderate suicide death rate (4.1 per 100,000 inhabitants, but the fact that it is a large country leads to the coexistence of diverse characteristics and levels of development across the different Brazilian regions. In this sense, the South region has been shown to present suicide rates above the national average. OBJECTIVE: To estimate the profile of suicide in municipalities comprising the Santa Catarina Coal Mining Region from 1980 to 2007. METHODS: This ecological, time-series, descriptive study sought to characterize epidemiological aspects related to suicide method, marital status, sex, age, and occupation in the municipalities of the region in the years 1980 to 2007. RESULTS: A total of 474 suicides occurred in the period, yielding a mean death rate of 10.83 per 100,000 inhabitants. There was a predominance of males, at a 5:1 ratio, and a peak rate in the 55-64-year age group (11.31 per 100,000 inhabitants. The suicide method most commonly used was hanging (72% and the most frequent occupation was hard labor work (11.60%; in relation to marital status, married subjects (48% were the ones with the highest rates of suicide. CONCLUSIONS: The Santa Catarina Coal Mining Region has suicide mortality rates above the national average. This study highlights specific characteristics of suicide in the region and may contribute to the development of preventive measures.

  3. Target hepatic artery regional chemotherapy and bevacizumab perfusion in liver metastatic colorectal cancer after failure of first-line or second-line systemic chemotherapy.

    Science.gov (United States)

    Chen, Hui; Zhang, Ji; Cao, Guang; Liu, Peng; Xu, Haifeng; Wang, Xiaodong; Zhu, Xu; Gao, Song; Guo, Jianhai; Zhu, Linzhong; Zhang, Pengjun

    2016-02-01

    Colorectal cancer liver metastasis (CRLM) is a refractory disease after failure of first-line or second-line chemotherapy. Bevacizumab is recommended as first-line therapy for advanced colorectal cancer, but is unproven in CRLM through the hepatic artery. We report favorable outcomes with targeted vessel regional chemotherapy (TVRC) for liver metastatic gastric cancer. TVRC with FOLFOX and bevacizumab perfusion through the hepatic artery was attempted for CRLM for efficacy and safety evaluation. In a single-institution retrospective observational study, 246 patients with CRLM after at least first-line or second-line failure of systemic chemotherapy received TVRC with FOLFOX (i.e. oxaliplatin, leucovorin, and 5-fluorouracil). Of 246 patients, 63 were enrolled into two groups: group 1 (n=30) received bevacizumab and TVRC following tumor progression during previous TVRC treatments; group 2 (n=33) received TVRC plus bevacizumab for CRLM on initiating TVRC. There were no significant differences in the median survival time (14.7 vs. 13.2 months, P=0.367), although the median time to progression was significant (3.3 vs. 5.5 months, P=0.026) between groups. No severe adverse events related to TVRC plus bevacizumab perfusion occurred. Target vessel regional chemotherapy with FOLFOX plus bevacizumab perfusion through the hepatic artery was effective and safe in CRLM. The optimal combination of TVRC and bevacizumab needs further confirmation in future phase II-III clinical trials.

  4. Correlation of antinuclear antibody immunofluorescence patterns with immune profile using line immunoassay in the Indian scenario

    Directory of Open Access Journals (Sweden)

    Sebastian Wendy

    2010-07-01

    Full Text Available Background: Immunity status, individual response to disease and types of antibodies produced are well known to vary from person to person, place to place and probably from population to population. A broad spectrum of specific auto antibodies that have so far been associated with specific rheumatic diseases, as noted in Western literature, has been well taken as a reference standard all over the world. There is neither research work nor any data correlating the auto antibodies and their antinuclear antibody (ANA patterns with the immunoprofile in the Indian population to date. Aims: To understand a definite association between ANA patterns and specific antibodies in the serum in the Indian study population and to document similarities / differences with the West. Settings and Design: This prospective and retrospective double blind study was undertaken on the South Indian population referred for ANA testing by Indirect Immunofluorescence method and by immunoline methods. Materials and Methods: Serum samples of patients from a random South Indian population who sought medical help for rheumatic disease were subjected for ANA testing by indirect immunofluorescence (IIF method and line immunoassay during the study period of 27 months. Serum samples were processed in dilution of 1:100 using HEp - 2010 / liver biochip (Monkey (EUROIMMUN AG. The serum samples which were further processed for line immunoassay were treated in 1:100 dilution on nylon strips coated with recombinant and purified antigens as discrete lines with plastic backing (EUROIMMUN AG coated with antigens nRNP / Sm, Sm, SSA, Ro-52, SSB, Scl-70, PM-Scl, PCNA, Jo-1, CENP-B, dsDNA, nucleosomes, histones, ribosomal protein-P, anti-mitochondrial antibodies (AMA-M2 along with a control band. The analysis was done by comparing the intensity of the reaction with positive control line by image analysis. Results: The antinuclear antibody indirect immunofluorescence (ANA - IIF patterns obtained

  5. On the orbital motion of cold clouds in broad-line regions

    Science.gov (United States)

    Shadmehri, Mohsen

    2015-08-01

    We study the orbit of a pressure-confined cloud in the broad-line region (BLR) of active galactic nuclei when the combined effects of the central gravity and anisotropic radiation pressure and the drag force are considered. The physical properties of the intercloud gas, such as its pressure and dynamic viscosity, are defined as power-law functions of the radial distance. For a drag force proportional to the relative velocity of a cloud and the background gas, a detailed analysis of the orbits is performed for different values of the input parameters. We also present analytical solutions for when the intercloud pressure is uniform and the viscosity is proportional to the inverse square of the radial distance. Our analytical and numerical solutions demonstrate decay of the orbits due to the drag force, so that a cloud will eventually fall on to the central region after the so-called time-of-flight. We found that the time-of-flight of a BLR cloud is proportional to the inverse of the dimensionless drag coefficient. If the time-of-flight becomes shorter than the lifetime of the whole system, then mechanisms for continually forming BLR clouds are needed.

  6. Analysis of magnetotelluric profile data from the Ruby Mountains metamorphic core complex and southern Carlin Trend region, Nevada

    Science.gov (United States)

    Wannamaker, Philip E.; Doerner, William M.; Stodt, John A.; Sodergen, Timothy L.; Rodriguez, Brian D.

    2002-01-01

    We have collected about 150 magnetotelluric (MT) soundings in northeastern Nevada in the region of the Ruby Mountains metamorphic core complex uplift and southern Carlin mineral trend, in an effort to illuminate controls on core complex evolution and deposition of world-class gold deposits. The region has experienced a broad range of tectonic events including several periods of compressional and extensional deformation, which have contributed to the total expression of electrical resistivity. Most of the soundings are in three east-west profiles across increasing degrees of core uplift to the north (Bald Mountain, Harrison Pass and Secret Pass latitudes). Two shorter lines cross a prominent east-west structure to the north of the northern profile. MT impedance tensor and vertical magnetic field rotations imply a N-NNE average regional geoelectric strike, similar to surface geologic trends. Model resistivity cross sections were derived using a 2-D inversion algorithm, which damps departures of model parameters from an a priori structure, emphasizing the transverse magnetic (TM) mode and vertical magnetic field data. Geological interpretation of the resistivity combines previous seismic, potential field and isotope models, structural and petrological models for regional compression and extension, and detailed structural/stratigraphic interpretations incorporating drilling for petroleum and mineral exploration. To first order, the resistivity structure is one of a moderately conductive, Phanerozoic sedimentary section fundamentally disrupted by intrusion and uplift of resistive crystalline rocks. Late Devonian and early Mississippian shales of the Pilot and Chainman Formations together form an important conductive marker sequence in the stratigraphy and show pronounced increases in conductance (conductivity-thickness product) from east to west. These increases in conductance are attributed to graphitization caused by Elko-Sevier era compressional shear deformation and

  7. Atmospheric profiling via satellite to satellite occultations near water and ozone absorption lines for weather and climate

    Science.gov (United States)

    Kursinski, E. R.; Ward, D.; Otarola, A. C.; McGhee, J.; Stovern, M.; Sammler, K.; Reed, H.; Erickson, D.; McCormick, C.; Griggs, E.

    2016-05-01

    Significantly reducing weather and climate prediction uncertainty requires global observations with substantially higher information content than present observations provide. While GPS occultations have provided a major advance, GPS observations of the atmosphere are limited by wavelengths chosen specifically to minimize interaction with the atmosphere. Significantly more information can be obtained via satellite to satellite occultations made at wavelengths chosen specifically to characterize the atmosphere. Here we describe such a system that will probe cm- and mmwavelength water vapor absorption lines called the Active Temperature, Ozone and Moisture Microwave Spectrometer (ATOMMS). Profiling both the speed and absorption of light enables ATOMMS to profile temperature, pressure and humidity simultaneously, which GPS occultations cannot do, as well as profile clouds and turbulence. We summarize the ATOMMS concept and its theoretical performance. We describe field measurements made with a prototype ATOMMS instrument and several important capabilities demonstrated with those ground based measurements including retrieving temporal variations in path-averaged water vapor to 1%, in clear, cloudy and rainy conditions, up to optical depths of 17, remotely sensing turbulence and determining rain rates. We conclude with a vision of a future ATOMMS low Earth orbiting satellite constellation designed to take advantage of synergies between observational needs for weather and climate, ATOMMS unprecedented orbital remote sensing capabilities and recent cubesat technological innovations that enable a constellation of dozens of very small spacecraft to achieve many critical, but as yet unfulfilled, monitoring and forecasting needs.

  8. Characterization of the glycosylation profile of the human breast cancer cell line, MDA-231, and a bone colonizing variant.

    Science.gov (United States)

    Carcel-Trullols, Jaime; Stanley, Joseph S; Saha, Rinku; Shaaf, Saeid; Bendre, Manali S; Monzavi-Karbassi, Behjatolah; Suva, Larry J; Kieber-Emmons, Thomas

    2006-05-01

    The mechanisms that guide organ-specific metastases are not fully established. The aberrant expression of carbohydrates may play a fundamental role in defining the molecular mechanisms for metastases to distant organs and facilitate positive interactions within the target organ. The purpose of the present study was to determine the glycomic profile of a variant of the MDA-MB-231 breast cancer cell line that colonizes the bone and to ascribe mechanistic functions mediated by carbohydrates that might correlate with clinical bone metastases. The carbohydrate expression profiles of osteolytic MDA-MET breast cancer cells and non-osteolytic parental MDA-MB-231 cells were determined. MDA-MET cells were derived from MDA-MB-231 cells by in vivo selection of metastatic bone lesions following intracardiac inoculation. The two related breast cancer cell lines expressed distinct carbohydrate profiles; MDA-MET cells displayed an increased expression of alpha (2,6) linked sialic acid, N-beta1-6 GlcNAc, and sialylated Lewis-A antigen, and decreased expression of Galbeta1,3GalNAc as detected using a combination of lectins and anti-carbohydrate antibodies. Microarray analysis demonstrated an increased expression of glycosyltransferase genes, correlative for the distinct glycomic phenotype. The altered glycomic phenotypes of MDA-MET cells include effects on the differential binding to bone marrow endothelial cells, enhanced ECM binding and an increase in invasive potential. These data suggest that the glycomic phenotype of MDA-MET cells is associated with a select set of accumulated functions that collectively impact on the bone metastases and bone colonization capacity of breast cancer cells.

  9. A Multi-line Study of Atomic Carbon and Carbon Monoxide in the Galactic Star- forming Region W3

    Science.gov (United States)

    Jakob, H.; Kramer, C.; Mookerjea, B.; Jeyakumar, S.; Stutzki, J.

    We present results from simultaneous observations of the fine structure line emissions of neutral carbon (C I) at 492 and 809 GHz from selected Galactic star forming regions. These observations include the first results using the the newly installed SMART (SubmilliMeter Array Receiver at Two wavelengths) on KOSMA. The regions observed were selected in order to cover a range of strengths of the incident UV radiation from the exciting star/stars and also densities of the interstellar medium. Extended maps of C I emission from massive star forming regions including W3, S106 and Orion BN/KL have been observed. Simultaneous observation of the two C I lines ensures better relative calibration. The results from these observations will be combined with observed intensities of low-J and mid-J CO and C+ lines and analyzed using radiation transfer based models for Photon Dominated Regions (PDRs).

  10. In Situ Characterizing Membrane Lipid Phenotype of Human Lung Cancer Cell Lines Using Mass Spectrometry Profiling

    OpenAIRE

    2016-01-01

    Abnormal lipid metabolisms are closely associated with cancers. In this study, mass spectrometry was employed to in situ investigate the associations of membrane lipid phenotypes of six human lung cancer cell lines (i.e., A549, H1650, H1975 from adenocarcinoma, H157 and H1703 from squamous cell carcinomas, and H460 from a large cell carcinoma) with cancer cell types and finally total 230 lipids were detected. Based these 230 lipids, partial least-square discriminant analysis indicated that fi...

  11. Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets

    Directory of Open Access Journals (Sweden)

    Espreafico Enilza M

    2008-01-01

    Full Text Available Abstract Background Melanoma progression occurs through three major stages: radial growth phase (RGP, confined to the epidermis; vertical growth phase (VGP, when the tumor has invaded into the dermis; and metastasis. In this work, we used suppression subtractive hybridization (SSH to investigate the molecular signature of melanoma progression, by comparing a group of metastatic cell lines with an RGP-like cell line showing characteristics of early neoplastic lesions including expression of the metastasis suppressor KISS1, lack of αvβ3-integrin and low levels of RHOC. Methods Two subtracted cDNA collections were obtained, one (RGP library by subtracting the RGP cell line (WM1552C cDNA from a cDNA pool from four metastatic cell lines (WM9, WM852, 1205Lu and WM1617, and the other (Met library by the reverse subtraction. Clones were sequenced and annotated, and expression validation was done by Northern blot and RT-PCR. Gene Ontology annotation and searches in large-scale melanoma expression studies were done for the genes identified. Results We identified 367 clones from the RGP library and 386 from the Met library, of which 351 and 368, respectively, match human mRNA sequences, representing 288 and 217 annotated genes. We confirmed the differential expression of all genes selected for validation. In the Met library, we found an enrichment of genes in the growth factors/receptor, adhesion and motility categories whereas in the RGP library, enriched categories were nucleotide biosynthesis, DNA packing/repair, and macromolecular/vesicular trafficking. Interestingly, 19% of the genes from the RGP library map to chromosome 1 against 4% of the ones from Met library. Conclusion This study identifies two populations of genes differentially expressed between melanoma cell lines from two tumor stages and suggests that these sets of genes represent profiles of less aggressive versus metastatic melanomas. A search for expression profiles of melanoma in

  12. The national psychological/personality profile of Romanians: An in depth analysis of the regional national psychological/personality profile of Romanians

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    David, D.

    2015-12-01

    Full Text Available In this article we perform an in depth analysis of the national psychological/personality profile of Romanians. Following recent developments in the field (see Rentfrow et al., 2013; 2015, we study the regional national psychological/personality profile of Romanians, based on the Big Five model (i.e., NEO PI/R. Using a representative sample (N1 = 1000, we performed a cluster analysis and identified two bipolar personality profiles in the population: cluster 1, called “Factor X-”, characterized by high neuroticism and low levels of extraversion, openness, agreeableness, and conscientiousness, and cluster 2, called “Factor X+”, characterized by the opposite configuration in personality traits, low neuroticism and high levels of extraversion, openness, agreeableness, and conscientiousness. The same two cluster pattern/solution emerged in other samples (N = 2200, with other Big Five-based instruments, and by using various methods of data (e.g., direct vs. reversed item score, controlling for item desirability and cluster (i.e., with and without “running means” analyses. These two profiles are quite evenly distributed in the overall population, but also across all geographical regions. Moreover, comparing the distribution of the five personality traits, we found just few small differences between the eight geographical divisions that we used for our analysis. These results suggest that the regional national psychological/personality profile of Romania is quite homogenous. Directions for harnessing the potential of both personality profiles are presented to the reader. Other implications based on the bipolar and fractal structure of the personality profile are discussed from an interdisciplinary perspective.

  13. Profiling polyphenols of two diploid strawberry (Fragaria vesca) inbred lines using UHPLC-HRMS(n.).

    Science.gov (United States)

    Sun, Jianghao; Liu, Xianjin; Yang, Tianbao; Slovin, Janet; Chen, Pei

    2014-03-01

    Phenolic compounds in the fruits of two diploid strawberries (Fragaria vesca f. semperflorens) inbred lines-Ruegen F7-4 (a red-fruited genotype) and YW5AF7 (a yellow-fruited genotype) were characterised using ultra-high-performance liquid chromatography coupled with tandem high-resolution mass spectrometry (UHPLC-HRMS(n)). The changes of anthocyanin composition during fruit development and between Ruegen F7-4 and YW5AF7 were studied. About 67 phenolic compounds, including taxifolin 3-O-arabinoside, glycosides of quercetin, kaempferol, cyanidin, pelargonidin, peonidin, ellagic acid derivatives, and other flavonols were identified in these two inbred lines. Compared to the regular octoploid strawberry, unique phenolic compounds were found in F. vesca fruits, such as taxifolin 3-O-arabinoside (both) and peonidin 3-O-malonylglucoside (Ruegen F7-4). The results provide the basis for comparative analysis of polyphenolic compounds in yellow and red diploid strawberries, as well as with the cultivated octoploid strawberries.

  14. Protein Profile of Human Lung Squamous Carcinoma Cell Line NCI-H226

    Institute of Scientific and Technical Information of China (English)

    HAO ZHANG; NA LI; YUE CHEN; LING-YUN HUANG; YI-CHING WANG; GANG FANG; DA-CHENG HE; XUE-YUAN XIAO

    2007-01-01

    Objective To construct a database of human lung squamous carcinoma cell line NCI-H226 and to facilitate discovery of novel subtypes markers of lung cancer. Method Proteomic technique was used to analyze human lung squamous carcinoma cell line NCI-H226. The proteins of the NCI-H226 cells were separated by two-dimensional gel electrophoresis and identified by mass spectrometry. Results The results showed that a good reproducibility of the 2-D gel pattern was attained. The position deviation of matched spots among three 2-D gels was 1.95±0.53 mm in the isoelectric focusing direction,and 1.73±0.45 mm in the sodium dodecyl sulfate-polyacrylamide gel electrophoresis direction. One hundred and twenty-seven proteins, including enzymes, signal transduction proteins, structure proteins, transport proteins, etc. were characterized, of which, 29 identified proteins in NCI-H226 cells were reported for the first time to be involved in lung cancer carcinogenesis.Conclusion The information obtained from this study could provide some valuable clues for further study on the carcinogenetic mechanism of different types of lung cancer, and may help us to discover some potential subtype-specific biomarkers of lung cancer.

  15. Spatial distribution of far-infrared rotationally excited CH+ and OH emission lines in the Orion Bar photodissociation region

    Science.gov (United States)

    Parikka, A.; Habart, E.; Bernard-Salas, J.; Goicoechea, J. R.; Abergel, A.; Pilleri, P.; Dartois, E.; Joblin, C.; Gerin, M.; Godard, B.

    2017-02-01

    Context. The methylidyne cation (CH+) and hydroxyl (OH) are key molecules in the warm interstellar chemistry, but their formation and excitation mechanisms are not well understood. Their abundance and excitation are predicted to be enhanced by the presence of vibrationally excited H2 or hot gas ( 500-1000 K) in photodissociation regions (PDRs) with high incident far-ultraviolet (FUV) radiation field. The excitation may also originate in dense gas (>105 cm-3) followed by nonreactive collisions with H2, H, and electrons. Previous observations of the Orion Bar suggest that the rotationally excited CH+ and OH correlate with the excited CO, which is a tracer of dense and warm gas, and that formation pumping contributes to CH+ excitation. Aims: Our goal is to examine the spatial distribution of the rotationally excited CH+ and OH emission lines in the Orion Bar to establish their physical origin and main formation and excitation mechanisms. Methods: We present spatially sampled maps of the CH+J = 3-2 transition at 119.8 μm and the OH Λ doublet at 84 μm in the Orion Bar over an area of 110″× 110″ with Herschel/PACS. We compare the spatial distribution of these molecules with those of their chemical precursors, C+, O and H2, and tracers of warm and dense gas (high-J CO). We assess the spatial variation of the CH+J = 2-1 velocity-resolved line profile at 1669 GHz with Herschel/HIFI spectrometer observations. Results: The OH and especially CH+ lines correlate well with the high-J CO emission and delineate the warm and dense molecular region at the edge of the Bar. While notably similar, the differences in the CH+ and OH morphologies indicate that CH+ formation and excitation are strongly related to the observed vibrationally excited H2. This, together with the observed broad CH+ line widths, indicates that formation pumping contributes to the excitation of this reactive molecular ion. Interestingly, the peak of the rotationally excited OH 84 μm emission coincides

  16. Lithologic descriptions and temperature profiles of five wells in the southwestern Valles caldera region, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Shevenell, L.; Goff, F.; Miles, D.; Waibel, A.; Swanberg, C.

    1988-01-01

    The subsurface stratigraphy and temperature profiles of the southern and western Valles caldera region have been well constrained with the use of data from the VC-1, AET-4, WC 23-4, PC-1 and PC-2 wells. Data from these wells indicate that thermal gradients west of the caldera margin are between 110 and 140)degrees)C/km, with a maximum gradient occurring in the bottom of PC-1 equal to 240)degrees)C/km as a result of thermal fluid flow. Gradients within the caldera reach a maximum of 350)degrees)C/km, while the maximum thermal gradient measured southwest of the caldera in the thermal outflow plume is 140)degrees)C/km. The five wells exhibit high thermal gradients (>60)deghrees)C/km) resulting from high conductive heat flow associated with the Rio Grande rift and volcanism in the Valles caldera, as well as high convective heat flow associated with circulating geothermal fluids. Gamma logs run in four of the five wells appear to be of limited use for stratigraphic correlations in the caldera region. However, stratigraphic and temperature data from the five wells provide information about the structure and thermal regime of the southern and western Valles caldera region. 29 refs., 9 figs. 2 tabs.

  17. Differential regional gray matter volumes in patients with on-line game addiction and professional gamers.

    Science.gov (United States)

    Han, Doug Hyun; Lyoo, In Kyoon; Renshaw, Perry F

    2012-04-01

    Patients with on-line game addiction (POGA) and professional video game players play video games for extended periods of time, but experience very different consequences for their on-line game play. Brain regions consisting of anterior cingulate, thalamus and occpito-temporal areas may increase the likelihood of becoming a pro-gamer or POGA. Twenty POGA, seventeen pro-gamers, and eighteen healthy comparison subjects (HC) were recruited. All magnetic resonance imaging (MRI) was performed on a 1.5 Tesla Espree MRI scanner (SIEMENS, Erlangen, Germany). Voxel-wise comparisons of gray matter volume were performed between the groups using the two-sample t-test with statistical parametric mapping (SPM5). Compared to HC, the POGA group showed increased impulsiveness and perseverative errors, and volume in left thalamus gray matter, but decreased gray matter volume in both inferior temporal gyri, right middle occipital gyrus, and left inferior occipital gyrus, compared with HC. Pro-gamers showed increased gray matter volume in left cingulate gyrus, but decreased gray matter volume in left middle occipital gyrus and right inferior temporal gyrus compared with HC. Additionally, the pro-gamer group showed increased gray matter volume in left cingulate gyrus and decreased left thalamus gray matter volume compared with the POGA group. The current study suggests that increased gray matter volumes of the left cingulate gyrus in pro-gamers and of the left thalamus in POGA may contribute to the different clinical characteristics of pro-gamers and POGA. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. High-resolution profiling of novel transcribed regions during rat spermatogenesis.

    Science.gov (United States)

    Chalmel, Frédéric; Lardenois, Aurélie; Evrard, Bertrand; Rolland, Antoine D; Sallou, Olivier; Dumargne, Marie-Charlotte; Coiffec, Isabelle; Collin, Olivier; Primig, Michael; Jégou, Bernard

    2014-07-01

    Mammalian spermatogenesis is a complex and highly orchestrated combination of processes in which male germline proliferation and differentiation result in the production of mature spermatozoa. If recent genome-wide studies have contributed to the in-depth analysis of the male germline protein-encoding transcriptome, little effort has yet been devoted to the systematic identification of novel unannotated transcribed regions expressed during mammalian spermatogenesis. We report high-resolution expression profiling of male germ cells in rat, using next-generation sequencing technology and highly enriched testicular cell populations. Among 20 424 high-confidence transcripts reconstructed, we defined a stringent set of 1419 long multi-exonic unannotated transcripts expressed in the testis (testis-expressed unannotated transcripts [TUTs]). TUTs were divided into 7 groups with different expression patterns. Most TUTs share many of the characteristics of vertebrate long noncoding RNAs (lncRNAs). We also markedly reinforced the finding that TUTs and known lncRNAs accumulate during the meiotic and postmeiotic stages of spermatogenesis in mammals and that X-linked meiotic TUTs do not escape the silencing effects of meiotic sex chromosome inactivation. Importantly, we discovered that TUTs and known lncRNAs with a peak expression during meiosis define a distinct class of noncoding transcripts that exhibit exons twice as long as those of other transcripts. Our study provides new insights in transcriptional profiling of the male germline and represents a high-quality resource for novel loci expressed during spermatogenesis that significantly contributes to rat genome annotation.

  19. POSTURAL PROFILE OF CLASSICAL BALLERINAS FROM THE VALE DO SÃO FRANCISCO REGION OF BRAZIL

    Directory of Open Access Journals (Sweden)

    JANNINI NASCIMENTO RIBEIRO

    Full Text Available ABSTRACT Objective: The study aimed to determine the association between postural changes and practice of classical ballet among ballerinas from Integrated Administrative Region of Development (RIDE in Polo Petrolina/PE and Juazeiro/BA. Methods: Cross-sectional observational study with 19 classical ballerinas aged over 15 years and at least 5 years of uninterrupted classical ballet practice. The anthropometric assessment included measurements of total body mass, height and body mass index (BMI. Postural evaluation was performed using the photogrammetric method with help of Posturograma(r and SAPO(c software. Results: The mean age was 25.3±11.7 years and the mean BMI was 21.4±2.9 kg/m². Approximately 74% of classical ballerinas had normal anthropometric profile. The postural profile of the classical ballerinas showed inclination and protrusion of the head, trunk rotation, rectification of cervical lordosis, increased thoracic kyphosis, increased lumbar lordosis, pelvic inclination and anteversion. Conclusion: The practice of ballet led to changes in body alignment of the classical ballerinas evaluated. The results points out to the need of postural re-education in order to contribute for the kinetic-functional balance of classical ballet practitioners.

  20. Dominance of pollutant aerosols over an urban region and its impact on boundary layer temperature profile

    Science.gov (United States)

    Talukdar, Shamitaksha; Jana, Soumyajyoti; Maitra, Animesh

    2017-01-01

    Collocated measurements of aerosol optical depth (AOD) and black carbon at different wavelengths over Kolkata, an urban region in eastern India, have been used to calculate aerosol single-scattering albedo (SSA). The wavelength dependence of SSA and AOD has been presented to discriminate the aerosol types over this highly populated metropolitan area. The spectral pattern shows that SSA decreases with wavelength for most of the time in a year and corresponding Ångström coefficient is greater than unity. These optical properties indicate the dominance of fine-mode pollutant particles over the city. The temperature lapse rate profile within the surface boundary layer has been found to be significantly influenced by the heating effect of fine-mode pollutants, and consequently, the growth of the convective processes in the lower troposphere is notably affected. In addition, a back trajectory analysis has also been presented to indicate that transported air masses can have significant impact on spectral pattern of SSA.

  1. Low-Profile Fully-Printed Multifrequency Monopoles Loaded with Complementary Metamaterial Transmission Line

    Directory of Open Access Journals (Sweden)

    Xue Li

    2015-04-01

    Full Text Available The design of a new class of multifrequency monopoles by loading a set of resonant-type complementary metamaterial transmission lines (CMTL is firstly presented. Two types of CMTL elements are comprehensively explored: the former is the epsilon negative (ENG one by loading complementary split ring resonators (CSRRs with different configurations on the signal strip, whereas the latter is the double negative (DNG one by incorporating the CSRRs and capacitive gaps. In both cases, the CMTLs are considered with different number of unit cells. By cautiously controlling the geometrical parameters of element structure, five antenna prototypes coving different communication standards (GSM, UMTS, DMB and WiMAX are designed, fabricated and measured. Numerical and experimental results illustrate that the zeroth-order resonance frequencies of the ENG and DNG monopoles are in desirable consistency. Moreover, of all operating frequencies the antennas exhibit fairly good impedance matching performances better than -10dB and quasi-omnidirectional radiation patterns.

  2. CONTINUUM INTENSITY AND [O i] SPECTRAL LINE PROFILES IN SOLAR 3D PHOTOSPHERIC MODELS: THE EFFECT OF MAGNETIC FIELDS

    Energy Technology Data Exchange (ETDEWEB)

    Fabbian, D.; Moreno-Insertis, F., E-mail: damian@iac.es, E-mail: fmi@iac.es [Instituto de Astrofísica de Canarias (IAC), E-38205 La Laguna, Tenerife (Spain)

    2015-04-01

    The importance of magnetic fields in three-dimensional (3D) magnetoconvection models of the Sun’s photosphere is investigated in terms of their influence on the continuum intensity at different viewing inclination angles and on the intensity profile of two [O i] spectral lines. We use the RH numerical radiative transfer code to perform a posteriori spectral synthesis on the same time series of magnetoconvection models used in our publications on the effect of magnetic fields on abundance determination. We obtain a good match of the synthetic disk-center continuum intensity to the absolute continuum values from the Fourier Transform Spectrometer (FTS) observational spectrum; the match of the center-to-limb variation synthetic data to observations is also good, thanks, in part, to the 3D radiation transfer capabilities of the RH code. The different levels of magnetic flux in the numerical time series do not modify the quality of the match. Concerning the targeted [O i] spectral lines, we find, instead, that magnetic fields lead to nonnegligible changes in the synthetic spectrum, with larger average magnetic flux causing both of the lines to become noticeably weaker. The photospheric oxygen abundance that one would derive if instead using nonmagnetic numerical models would thus be lower by a few to several centidex. The inclusion of magnetic fields is confirmed to be important for improving the current modeling of the Sun, here in particular in terms of spectral line formation and of deriving consistent chemical abundances. These results may shed further light on the still controversial issue regarding the precise value of the solar oxygen abundance.

  3. Small RNA Profiles of the Rice PTGMS Line Wuxiang S Reveal miRNAs Involved in Fertility Transition.

    Science.gov (United States)

    Zhang, Hongyuan; Hu, Jihong; Qian, Qian; Chen, Hao; Jin, Jing; Ding, Yi

    2016-01-01

    MicroRNAs (miRNAs) play key roles in the regulation of plant growth and developmental processes. In this study, RNA-seq was used to examine the expression profiles of miRNAs in a novel, photo-thermosensitive genic male sterile (PTGMS) rice line, Wuxiang S (WXS), during fertility transition. A total of 497 known miRNAs and 273 novel miRNAs were identified. In a differential expression analysis, 26 miRNAs exhibited significant differential expression between WXS (Sterile, S) and WXS (Fertile, F). Some of these miRNAs were validated by quantitative real-time PCR. Among these miRNAs, 11 showed decreased expression levels, and 15 showed increased expression levels in WXS (S) compared to WXS (F). Some of these miRNAs, such as osa-miR156a-j, osa-miR164d, and osa-miR528, were shown to be negatively correlated with their targets. These targets have previously been reported to be related to pollen development and male sterility, suggesting that these miRNAs may be involved in the regulation of pollen development in the rice PTGMS line WXS. Furthermore, miRNA-mediated editing events were also observed. In this study, a possible model for the control of signaling pathways during the process of fertility transition in the rice PTGMS line WXS by miRNAs was developed. These findings contribute to our understanding of the roles of miRNAs during anther development in PTGMS lines in rice.

  4. Gene expression profile differences in high and low metastatic human ovarian cancer cell lines by gene chip

    Institute of Scientific and Technical Information of China (English)

    许沈华; 牟瀚舟; 吕桂泉; 朱赤红; 羊正炎; 高永良; 楼洪坤; 刘祥麟; 程勇; 杨文

    2002-01-01

    Objectives To study the difference between gene expressions of high (H0-8910PM) and low (HO-8910) metastatic human ovarian carcinoma cell lines and screen novel associated genes by cDNA microarray. Methods cDNA retro-transcribed from equal quantities of mRNA derived from high and low metastatic tumor cells or normal ovarian tissues were labeled with Cy5 and Cy3 fluorescein as probes. The mixed probe was hybridized with two pieces of BioDoor 4096 double dot human whole gene chip and scanned with a ScanArray 3000 laser scanner. The acquired image was analyzed by ImaGene 3.0 software. Results A total of 355 genes with expression levels more than 3 times larger were found by comparing the HO-8910 cell with normal ovarian epithelial cells. A total of 323 genes with expression levels more than 3 times larger in HO-8910PM cells compared to normal ovarian epithelium cells were also detected. A total of 165 genes whose expression levels were more than two times those of HO-8910PM cells compared to their mother cell line (HO-8910) were detected. Twenty-one genes with expression levels >3 times were found from comparison of these two tumor cell lines.Conclusions cDNA microarray techniques are effective in screening differential gene expression between two human ovarian cancer cell lines (H0-8910PM; HO-8910) and normal ovarian epithelial cells. These genes may be related to the genesis and development of ovarian carcinoma. Analysis of the human ovarian cancer gene expression profile with cDNA microarray may help in gene diagnosis, treatment and prevention.

  5. Modelling photometric reverberation data -- a disk-like broad line region and larger black hole mass for 3C120

    CERN Document Server

    Nuñez, F Pozo; Ramolla, M; Westhues, C; Haas, M; Chini, R; Steenbrugge, K; Lemke, R; Murphy, M

    2013-01-01

    We consider photometric reverberation mapping, where the nuclear continuum variations are monitored via a broad band filter and the echo of emission line clouds of the broad line region (BLR) is measured with a suitable narrow band (NB) filter. We investigate how an incomplete emission line coverage by the NB filter influences the BLR size determination. This includes two basic cases: 1) a symmetric cut of the blue and red part of the line wings, and 2) the filter positioned asymmetrically to the line center so that essentially a complete half of the emission line is contained in the NB filter. We find that symmetric cutting of line wings may lead to an overestimate of the BLR size which is less than 5%. The case of asymmetric line coverage, as for our data of the Seyfert-1 galaxy 3C120, yields the BLR size with less than 1% bias. Our results suggest that any BLR size bias due to narrow-band line cut in photometric reverberation mapping is small and in most cases negligible. We use well sampled photometric re...

  6. Line Intensities of (12)C(16)O(2) in the 1.2-1.4 µm Spectral Region.

    Science.gov (United States)

    Teffo; Claveau; Kou; Guelachvili; Ubelmann; Perevalov; Tashkun

    2000-06-01

    The 7000-8500 cm(-1) spectral region of (12)C(16)O(2) has been investigated using the high-resolution FT spectrometer of LPPM in Orsay. The two strongest bands in this region are the 10031 <-- 00001 and 10032 <-- 00001 bands centered at 8294 and 8192 cm(-1). Line intensities in these two bands and in the 40013 <-- 00001 and 40014 <-- 00001 bands have been measured. Using the method of effective operators, these line intensities have been included in a new fit of effective dipole-moment parameters to all available experimental data in the same spectral region of (12)C(16)O(2). The corresponding calculated line intensities of the 10031 <-- 00001 and 10032 <-- 00001 bands are compared with the experimental ones. Copyright 2000 Academic Press.

  7. Line Intensities of 12C 16O 2 in the 1.2-1.4 μm Spectral Region

    Science.gov (United States)

    Teffo, J.-L.; Claveau, C.; Kou, Q.; Guelachvili, G.; Ubelmann, A.; Perevalov, V. I.; Tashkun, S. A.

    2000-06-01

    The 7000-8500 cm-1 spectral region of 12C16O2 has been investigated using the high-resolution FT spectrometer of LPPM in Orsay. The two strongest bands in this region are the 10031 ← 00001 and 10032 ← 00001 bands centered at 8294 and 8192 cm-1. Line intensities in these two bands and in the 40013 ← 00001 and 40014 ← 00001 bands have been measured. Using the method of effective operators, these line intensities have been included in a new fit of effective dipole-moment parameters to all available experimental data in the same spectral region of 12C16O2. The corresponding calculated line intensities of the 10031 ← 00001 and 10032 ← 00001 bands are compared with the experimental ones.

  8. A Methodology for Long-Term Analysis of Innovative Signalling Systems on Regional Rail Lines

    Directory of Open Access Journals (Sweden)

    Luca D'Acierno

    2016-10-01

    Full Text Available A rail system may be considered a useful tool for reducing vehicular flows on a road system (i.e. cars and trucks, especially in high-density contexts such as urban and metropolitan areas where greenhouse gas emissions need to be abated. In particular, since travellers maximise their own utility, variations in mobility choices can be induced only by significantly improving the level-of-service of public transport. Our specific proposal is to identify the economic and environmental effects of implementing an innovative signalling system (which would reduce passenger waiting times by performing a cost-benefit analysis based on a feasibility threshold approach. Hence, it is necessary to calculate long-term benefits and compare them with intervention costs. In this context, a key factor to be considered is travel demand estimation in current and future conditions. This approach was tested on a regional rail line in southern Italy to show the feasibility and utility of the proposed methodology.

  9. Correlations among Jet, Accretion Disk, and Broad Line Region of Flat Spectrum Radio Quasars

    CERN Document Server

    Zhang, Jin; He, Jian-Jian; Liang, En-Wei; Zhang, Shuang-Nan

    2015-01-01

    The SEDs of 18 GeV FSRQs are collected and compiled from literature, in which both the jet emission and the accretion disk radiation can be observed, in order to investigate the correlations among their jet power (P_jet), accretion disk luminosity (L_disk), and luminosity of broad line region (BLR, L_BLR). On the basis of the SED fits with the jet radiation and accretion disk radiation models, we calculate P_jet and L_disk. No correlation between P_jet with either L_disk or L_BLR is found. With a sub-sample of L_BLR for 13 GeV FSRQs, it is observed that L_BLR is strongly correlated with their L_disk. We also study the BLR covering factors of the GeV FSRQs in our sample, averagely which are smaller than that of the large samples of radio-loud and radio-quiet quasars. P_jet of some GeV FSRQs is higher than L_disk, but P_jet of all the GeV FSRQs is lower than the accretion power of black hole (BH), which is estimated by \\dot{M}c^2=L_disk/0.1, indicating that the total accretion power of BH is sufficient to drive...

  10. Numerical Study on Outflows in Seyfert Galaxies I: Narrow Line Region Outflows in NGC 4151

    Science.gov (United States)

    Mou, Guobin; Wang, Tinggui; Yang, Chenwei

    2017-07-01

    The origin of narrow line region (NLR) outflows remains unknown. In this paper, we explore the scenario in which these outflows are circumnuclear clouds driven by energetic accretion disk winds. We choose the well-studied nearby Seyfert galaxy NGC 4151 as an example. By performing 3D hydrodynamical simulations, we are able to reproduce the radial distributions of velocity, mass outflow rate, and kinetic luminosity of NLR outflows in the inner 100 pc deduced from spatial resolved spectroscopic observations. The demanded kinetic luminosity of disk winds is about two orders of magnitude higher than that inferred from the NLR outflows, but is close to the ultrafast outflows (UFO) detected in the X-ray spectrum and a few times lower than the bolometric luminosity of the Seyfert. Our simulations imply that the scenario is viable for NGC 4151. The existence of the underlying disk winds can be confirmed by their impacts on higher density ISM, e.g., shock excitation signs, and the pressure in NLR.

  11. Mapping the Kinematics of the Narrow-Line Region in the Seyfert Galaxy NGC 4151

    CERN Document Server

    Das, V; Hutchings, J B; Deo, R P; Krämer, S B; Gull, T R; Kaiser, M E; Nelson, C H; Weistrop, D

    2005-01-01

    Using The Hubble Space Telescope's Space Telescope Imaging Spectrograph HST's STIS, observations of the OIII emission from the narrow-line region (NLR) of NGC 4151 were obtained and radial velocities determined. Five orbits of HST time were used to obtain spectra at five parallel slit configurations, at a position angle of 58 degrees, with spatial resolution 0.2 arcseconds across and 0.1 arcseconds along each slit. A spectral resolving power of ~ 9,000 with the G430M grating gave velocity measurements accurate to ~ 34 km/s. A kinematic model was generated to match the radial velocities, for comparison to previous kinematic models of biconical radial outflow developed for low-dispersion spectra at two slit positions. The new high-resolution spectra permit the measurement of accurate velocity dispersions for each radial-velocity component. The full-width at half-maximum (FWHM) reaches a maximum of 1000 km/s near the nucleus, and generally decreases with increasing distance to about 100 km/s in the extended narr...

  12. ISO observations and models of galaxies with Hidden Broad Line Regions

    CERN Document Server

    Efstathiou, A

    2005-01-01

    In this paper we present ISO mid-infrared spectrophotometry and far-infrared photometry of galaxies with Hidden Broad Line Regions (HBLR). We also present radiative transfer models of their spectral energy distributions which enable us to separate the contributions from the dusty disc of the AGN and the dusty starbursts. We find that the combination of tapered discs (discs whose thickness increases with distance from the central source in the inner part but stays constant in the outer part) and starbursts provide good fits to the data. The tapered discs dominate in the mid-infrared part of the spectrum and the starbursts in the far-infrared. After correcting the AGN luminosity for anisotropic emission we find that the ratio of the AGN luminosity to the starburst luminosity, L(AGN)/L(SB), ranges from about unity for IRAS14454-4343 to about 13 for IRAS01475-0740. Our results suggest that the warm IRAS colours of HBLR are due to the relatively high L(AGN)/L(SB). Our fits are consistent with the unified model and...

  13. Quasar cartography: From black hole to broad-line region scales

    Energy Technology Data Exchange (ETDEWEB)

    Chelouche, Doron [Department of Physics, Faculty of Natural Sciences, University of Haifa, Haifa 31905 (Israel); Zucker, Shay, E-mail: doron@sci.haifa.ac.il, E-mail: shayz@post.tau.ac.il [Department of Geophysical, Atmospheric, and Planetary Sciences, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)

    2013-06-01

    A generalized approach to reverberation mapping (RM) is presented, which is applicable to broad- and narrowband photometric data, as well as to spectroscopic observations. It is based on multivariate correlation analysis techniques and, in its present implementation, is able to identify reverberating signals across the accretion disk and the broad-line region (BLR) of active galactic nuclei (AGNs). Statistical tests are defined to assess the significance of time-delay measurements using this approach, and the limitations of the adopted formalism are discussed. It is shown how additional constraints on some of the parameters of the problem may be incorporated into the analysis thereby leading to improved results. When applied to a sample of 14 Seyfert 1 galaxies having good-quality high-cadence photometric data, accretion disk scales and BLR sizes are simultaneously determined, on a case-by-case basis, in most objects. The BLR scales deduced here are in good agreement with the findings of independent spectroscopic RM campaigns. Implications for the photometric RM of AGN interiors in the era of large surveys are discussed.

  14. Water-vapor line broadening and shifting by air, nitrogen, oxygen, and argon in the 720-nm wavelength region

    Science.gov (United States)

    Grossmann, Benoist E.; Browell, Edward V.

    1989-01-01

    High-resolution spectroscopic measurements of H2O vapor in the 720-nm wavelength region were conducted to investigate the broadening and shifting of H2O lines by air, nitrogen, oxygen, and argon over a wide range of pressures and temperatures. For each of the buffer gases under study, a linear relationship was found between the widths and the shifts, with the broader lines having the smaller pressure shifts. The pressure shifts measured compared favorably with theoretical values reported by Bykov et al. (1988). The temperature-dependence exponents for air-broadening were found to be J-dependent, with the lower-J lines having the higher exponents.

  15. An FE Based On-line Model for the Prediction of Work Roll Thermal Profile in Hot Strip Rolling

    Science.gov (United States)

    Choi, Ji Won; Lee, Jung Hyeung; Sun, Cheng Gang; Hwang, Sang Moo

    2010-06-01

    Prediction and control of the thermal deformation of the work roll is vital for enhancing product quality in hot strip and plate rolling. In this paper, we present an on-line model for the prediction of the work roll thermal profile. The model is developed on the basis of an integrated finite element model for the coupled analysis of heat transfer and deformation occurring at the bite zone, to rigorously take into account the effect of various rolling parameters on the thermal behavior of the work roll. The validity of the model is demonstrated through comparison with measurements made in an industrial hot strip mill. Also, an emphasis is given to the examination the effect of some selected rolling parameters in an actual production environment.

  16. A CORRELATION BETWEEN Lyα SPECTRAL LINE PROFILE AND REST-FRAME UV MORPHOLOGY

    Energy Technology Data Exchange (ETDEWEB)

    Vivian U; Hemmati, Shoubaneh; Darvish, Behnam; Mobasher, Bahram; Nayyeri, Hooshang; Mallery, Ryan [Department of Physics and Astronomy, University of California, Riverside, 900 University Avenue, Riverside, CA 92521 (United States); Dickinson, Mark [National Optical Astronomy Observatory, Tucson, AZ 85719 (United States); Stern, Daniel [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Mail Stop 169-221, Pasadena, CA 91109 (United States); Spinrad, Hyron, E-mail: vivianu@ucr.edu [Department of Astronomy, University of California, Berkeley, CA 94720 (United States)

    2015-12-10

    We explore the relationship between the spectral shape of the Lyα emission and the UV morphology of the host galaxy using a sample of 304 Lyα-emitting BVi-dropouts at 3 < z < 7 in the Great Observatories Origins Deep Survey and Cosmic Evolution Survey fields. Using our extensive reservoir of high-quality Keck DEIMOS spectra combined with Hubble Space Telescope WFC3 data, we measure the Lyα line asymmetries for individual galaxies and compare them to axial ratios measured from observed J- and H-band (restframe UV) images. We find that the Lyα skewness exhibits a large scatter at small elongation (a/b < 2), and this scatter decreases as the axial ratio increases. Comparison of this trend to radiative transfer models and various results from the literature suggests that these high-redshift Lyα emitters are not likely to be intrinsically round and symmetric disks, but they probably host galactic outflows traced by Lyα emitting clouds. The ionizing sources are centrally located, and the optical depth is a good indicator of the absorption and scattering events on the escape path of Lyα photons from the source. Our results find no evidence of evolution in Lyα asymmetry or axial ratio with look-back time.

  17. A Correlation Between Ly{\\alpha} Spectral Line Profile and Rest-Frame UV Morphology

    CERN Document Server

    U, Vivian; Darvish, Behnam; Mobasher, Bahram; Nayyeri, Hooshang; Dickinson, Mark; Stern, Daniel; Spinrad, Hyron; Mallery, Ryan

    2015-01-01

    We explore the relationship between the spectral shape of the Ly{\\alpha} emission and the UV morphology of the host galaxy using a sample of 304 Ly{\\alpha}-emitting BV i-dropouts at 3 < z < 7 in the GOODS and COSMOS fields. Using our extensive reservoir of high-quality Keck DEIMOS spectra combined with HST WFC3 data, we measure the Ly{\\alpha} line asymmetries for individual galaxies and compare them to axial ratios measured from observed J- and H-band (restframe UV) images. We find that the Ly{\\alpha} skewness exhibits a large scatter at small elongation (a/b < 2), and this scatter decreases as axial ratio increases. Comparison of this trend to radiative transfer models and various results from literature suggests that these high-redshift Ly{\\alpha} emitters are not likely to be intrinsically round and symmetric disks, but they probably host galactic outflows traced by Ly{\\alpha} emitting clouds. The ionizing sources are centrally located, with the optical depth a good indicator of the absorption and...

  18. ESSEA On-Line Courses and the WestEd Eisenhower Regional Consortium (WERC)

    Science.gov (United States)

    Rognier, E.

    2001-12-01

    The WestEd Eisenhower Regional Consortium (WERC) is in its second year of offering two Earth Systems Science On-line Graduate courses from IGES - one for High School teachers, and one for Middle School teachers. These high-quality courses support WERC's commitment to "supporting increased scientific and mathematical literacy among our nation's youth through services and other support aimed at enhancing the efforts of those who provide K-12 science and mathematics education." WERC has been able to use its EdGateway online community network to offer these courses to environmental education and science teachers nationwide. Through partnerships with the North American Association for Environmental Education (NAAEE), the National Environmental Education Advancement Project (NEEAP), and other regional, state and local science and environmental education organizations, WERC has a broad reach in connecting with science educators nationwide. WERC manages several state and national listservs, which enable us to reach thousands of educators with information about the courses. EdGateway also provides a private online community in which we offer the courses. WERC partners with two Master Teachers from Utah, who facilitate the courses, and with the Center for Science and Mathematics Education at Weber State University, who provides low-cost graduate credit for the courses. Our students have included classroom teachers from upper elementary through high school, community college science teachers, and environmental science center staff who provide inservice for teachers. Educators from Hawaii to New Jersey have provided diverse personal experiences of Earth Systems Science events, and add richness to the online discussions. Two Earth Science Experts, Dr. Rick Ford from Weber State University, and Dr. Art Sussman from WestEd also contribute to the high caliber of learning the students experience in the courses. (Dr. Sussman's book, Dr. Art's Guide to Planet Earth, is used as one of

  19. Microstructure and texture of electrodeposited Ni–ZrC composite coatings investigated by Rietveld XRD line profile analysis

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Zhongquan; Jiang, Chuanhai, E-mail: jiangchuanhai211@163.com; Fu, Peng; Cai, Fei; Ma, Naiheng

    2015-03-25

    Highlights: • Microstructure of Ni–ZrC electrodeposits is studied by Rietveld refinement. • Rietveld refinement software is used to simulate the pole figures of Ni–ZrC. • The RTC, simulated and measured pole figures are coincident with each other. • Influence of current density on the texture of Ni–ZrC is studied. - Abstract: Rietveld X-ray diffraction (XRD) line profile analysis method was used to investigate the influence of applied current density on the microstructure and texture of the electrodeposited Ni–ZrC composite coatings. Crystallite size, microstrain, distribution of crystallite size, dislocation density, crystalline preferred orientation (texture), and ZrC particles content of the Ni–ZrC coatings were obtained from the Rietveld XRD line profile analysis. The results show that the crystallite size of Ni–ZrC coating increases, the microstrain and dislocation density decrease with the increasing of the current density. And the distribution of crystallite size is less uniform at higher current density. The pole figures simulated by Rietveld analysis software are coincident with the measured pole figures of Ni–ZrC coatings. The calculated relative texture coefficient (RTC) values, the simulated and measured pole figures of the coatings all illustrate that the texture of Ni–ZrC coating is modified from weak (2 2 0) to strong (2 0 0) texture with the increasing of applied current density. The microstructure evolution of Ni–ZrC composites is ascribed to the change of applied current density and ZrC content in the coatings.

  20. IDENTIFIKASI PROFIL DASAR LAUT MENGGUNAKAN INSTRUMEN SIDE SCAN SONAR DENGAN METODE BEAM PATTERN DISCRETE-EQUI-SPACED UNSHADED LINE ARRAY

    Directory of Open Access Journals (Sweden)

    Muhammad Zainuddin Lubis

    2017-05-01

    Full Text Available Laut Punggur merupakan laut yang terletak di Batam, Kepulauan Riau yang mempunyai beragam habitat objek,dan bentuk struktur bawah laut yang memiliki dinamika laut yang sangat tinggi. Side scan sonar (SSS merupakan instrumen pengembangan sistem sonar yang mampu menunjukkan dalam gambar dua dimensional permukaan dasar laut dengan kondisi kontur, topografi, dan target secara bersamaan. Metode Beam Pattern Discrete-Equi-Spaced Unshaded Line Array digunakan untuk menghitung beam pattern dua dimensi yang tergantung pada sudut dari gelombang suara yang masuk dari sumbu array yang diterima tergantung pada sudut di mana sinar suara pada array. Penelitian ini dilakukan pada Desember 2016 di laut Punggur,Batam, Kepulauan Riau-Indonesia, dengan koordinat 104 ° 08,7102 E dan 1° 03,2448 N sampai 1 ° 03.3977 N dan 104 ° 08,8133 E, menggunakan instrumen Side Scan Sonar C-Max CM2 Tow fish dengan frekuensi 325 kHz. Hasil yang diperoleh dari perekaman terdapat 7 target, dan Beam pattern dari metode Beam Discrete-Equi-Spaced Unshaded Line Array target 4 memiliki nilai tertinggi pada directivity Pattern yaitu 21.08 dB. Hasil model beam pattern ini memiliki nilai pusat pada incidence angle (o terhadap Directivity pattern (dB tidak berada di nilai 0 ataupun pada pusat beam pattern yang dihasilkan pada target 6 dengan nilai incident angle -1.5 o dan 1.5o mengalami penurunan hingga -40 dB. Karakteristik sedimen dasar perairan di laut punggur ditemukan lebih banyak pasir. Hasil metode Beam Discrete-Equi-Spaced Unshaded Line Array ditemukan bangkai kapal tenggelam.Kata Kunci: Side Scan Sonar, Beam Pattern Discrete-Equi-Spaced Unshaded Line Array, Incidence angle, Directivity pattern IDENTIFICATION OF SEABED PROFILE USING SIDE SCAN SONAR INSTRUMENT WITH PATTERN DISCRETE-EQUI-SPACED UNSHADED LINE ARRAY METHODRiau Islands is an island that has a variety of habitat objects, and forms of submarine structures that have a very high ocean dynamics, Punggur Sea is the sea

  1. Profiling the progression of cancer: separation of microsomal proteins in MCF10 breast epithelial cell lines using nonporous chromatophoresis.

    Science.gov (United States)

    O'Neil, Kimberly A; Miller, Fred R; Barder, Timothy J; Lubman, David M

    2003-07-01

    The heterogeneity of cellular protein expression has stimulated development of separations targeting smaller groups of related proteins rather than entire proteomes. The following work describes the development of a technique for the characterization of membrane subproteomes from five different breast epithelial cell lines. Intact membrane proteins are separated by hydrophobicity in the first dimension using nonporous reversed-phase high-performance liquid chromatography (RP-HPLC) to generate unique chromatographic profiles. Fractions of eluent are further separated using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) to create distinct banding patterns. This hybrid liquid phase/gel phase method circumvents issues of membrane protein precipitation and provides a simple strategy aimed at isolating and characterizing a traditionally underrepresented protein class. Membrane protein profiles are created that discriminate between microsomal fractions of breast epithelial cells in different stages of neoplastic progression. Proteins are subsequently identified using matrix-assisted laser desorption/ionization - mass spectrometry (MALDI-MS) mass fingerprinting and MALDI-quadrupole time of flight - tandem mass spectrometry (QTOF-MS/MS) peptide sequencing. Furthermore, as this strategy preserves intact protein structure, further characterization can be performed on proteins producing mass fingerprint spectra and fragmentation spectra that did not result in database protein identifications. The coupling of nonporous RP-HPLC with SDS-PAGE provides a useful alternative to two-dimensional PAGE (2-D-PAGE) for membrane protein analysis.

  2. First in situ evidence of electron pitch angle scattering due to magnetic field line curvature in the Ion diffusion region

    Science.gov (United States)

    Zhang, Y. C.; Shen, C.; Marchaudon, A.; Rong, Z. J.; Lavraud, B.; Fazakerley, A.; Yao, Z.; Mihaljcic, B.; Ji, Y.; Ma, Y. H.; Liu, Z. X.

    2016-05-01

    Theory predicts that the first adiabatic invariant of a charged particle may be violated in a region of highly curved field lines, leading to significant pitch angle scattering for particles whose gyroradius are comparable to the radius of the magnetic field line curvature. This scattering generates more isotropic particle distribution functions, with important impacts on the presence or absence of plasma instabilities. Using magnetic curvature analysis based on multipoint Cluster spacecraft observations, we present the first investigation of magnetic curvature in the vicinity of an ion diffusion region where reconnected field lines are highly curved. Electrons at energies > 8 keV show a clear pitch angle ordering between bidirectional and trapped distribution in surrounding regions, while we show that in the more central part of the ion diffusion region electrons above such energies become isotropic. By contrast, colder electrons (~1 keV) retain their bidirectional character throughout the diffusion regions. The calculated adiabatic parameter K2 for these electrons is in agreement with theory. This study provides the first observational evidence for particle pitch angle scattering due to magnetic field lines with well characterized curvature in a space plasma.

  3. Profile of Exosomal and Intracellular microRNA in Gamma-Herpesvirus-Infected Lymphoma Cell Lines

    Science.gov (United States)

    Hoshina, Shiho; Sekizuka, Tsuyoshi; Kataoka, Michiyo; Hasegawa, Hideki; Hamada, Hiromichi; Kuroda, Makoto; Katano, Harutaka

    2016-01-01

    Exosomes are small vesicles released from cells, into which microRNAs (miRNA) are specifically sorted and accumulated. Two gamma-herpesviruses, Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein—Barr virus (EBV), encode miRNAs in their genomes and express virus-encoded miRNAs in cells and exosomes. However, there is little information about the detailed distribution of virus-encoded miRNAs in cells and exosomes. In this study, we thus identified virus- and host-encoded miRNAs in exosomes released from KSHV- or EBV-infected lymphoma cell lines and compared them with intracellular miRNAs using a next-generation sequencer. Sequencing analysis demonstrated that 48% of the annotated miRNAs in the exosomes from KSHV-infected cells originated from KSHV. Human mir-10b-5p and mir-143-3p were much more highly concentrated in exosomes than in cells. Exosomes contained more nonexact mature miRNAs that did not exactly match those in miRBase than cells. Among the KSHV-encoded miRNAs, miRK12-3-5p was the most abundant exact mature miRNA in both cells and exosomes that exactly matched those in miRBase. Recently identified EXOmotifs, nucleotide motifs that control the loading of miRNAs into exosomes were frequently found within the sequences of KSHV-encoded miRNAs, and the presence of the EXOmotif CCCT or CCCG was associated with the localization of miRNA in exosomes in KSHV-infected cells. These observations suggest that specific virus-encoded miRNAs are sorted by EXOmotifs and accumulate in exosomes in virus-infected cells. PMID:27611973

  4. High-definition DNA methylation profiles from breast and ovarian carcinoma cell lines with differing doxorubicin resistance.

    Directory of Open Access Journals (Sweden)

    Michael Boettcher

    Full Text Available Acquired drug resistance represents a frequent obstacle which hampers efficient chemotherapy of cancers. The contribution of aberrant DNA methylation to the development of drug resistant tumor cells has gained increasing attention over the past decades. Hence, the objective of the presented study was to characterize DNA methylation changes which arise from treatment of tumor cells with the chemotherapeutic drug doxorubicin. DNA methylation levels from CpG islands (CGIs linked to twenty-eight genes, whose expression levels had previously been shown to contribute to resistance against DNA double strand break inducing drugs or tumor progression in different cancer types were analyzed. High-definition DNA methylation profiles which consisted of methylation levels from 800 CpG sites mapping to CGIs around the transcription start sites of the selected genes were determined. In order to investigate the influence of CGI methylation on the expression of associated genes, their mRNA levels were investigated via qRT-PCR. It was shown that the employed method is suitable for providing highly accurate methylation profiles, comparable to those obtained via clone sequencing, the gold standard for high-definition DNA methylation studies. In breast carcinoma cells with acquired resistance against the double strand break inducing drug doxorubicin, changes in methylation of specific cytosines from CGIs linked to thirteen genes were detected. Moreover, similarities between methylation profiles obtained from breast and ovarian carcinoma cell lines with acquired doxorubicin resistance were found. The expression levels of a subset of analyzed genes were shown to be linked to the methylation levels of the analyzed CGIs. Our results provide detailed DNA methylation information from two separate model systems for acquired doxorubicin resistance and suggest the occurrence of similar methylation changes in both systems upon exposure to the drug.

  5. The complexity of the coronal line region in AGNs: Gas-jet interactions and outflows revealed by NIR spectroscopy

    Science.gov (United States)

    Rodríguez-Ardila, Alberto; Prieto, Almudena; Mazzalay, Ximena

    2016-08-01

    Apart from the classical broad line region (BLR) at small core distances, and the extended classical narrow-line region (NLR), a subset of active galactic nuclei (AGN) show, in their spectra, lines from very highly ionised atoms, known as Coronal lines (CLs). The precise nature and origin of these CLs remain uncertain. Advances on this matter include the determination of the size and morphology of the CLR by means of optical HST and ground-based AO imaging/spectroscopy in a few AGNs. The results indicate CLRs with sizes varying from compact (~30 pc) to extended (~200 pc) emission and aligned preferentially with the direction of the lower ionisation cones seen in these sources. In this talk, we present results of a pioneering work aimed at studying the CLR in the near-infrared region on a selected sample of nearby AGNs. The excellent angular resolution of the data allowed us to resolve and map the extension of the coronal line gas and compare it to that emitting low- and mid-ionization lines. In most cases, the very good match between the radio emission and the CLR suggest that at least part of the high-ionization gas is jet-driven. Results from photoionization models where the central engine is the only source of energy input strongly fail at reproducing the observed line ratios, mainly at distances larger than 60 pc from the centre. We discuss here other processes that should be at work to enhance this energetic emission and suggest that the presence of coronal lines in AGNs is an unambiguous signature of feedback processes in these sources.

  6. Vertical Profiles of Ammonia in the Colorado Front Range: Impacts of Source Region and Meteorology

    Science.gov (United States)

    Tevlin, A.; Kaushik, A.; Noone, D. C.; Ortega, J. V.; Smith, J. N.; Brophy, P.; Kirkland, J.; Link, M. F.; Farmer, D. K.; Wolfe, D. E.; Dube, W. P.; McDuffie, E. E.; Brown, S. S.; Zaragoza, J.; Fischer, E. V.; Murphy, J. G.

    2014-12-01

    Atmospheric ammonia plays an important role in aerosol particle formation and growth, as well as in nitrogen deposition to sensitive ecosystems. However, significant uncertainties are associated with the distribution and strength of emission sources, and many of the processes that control its atmospheric fate are not fully understood. The high density of agricultural and urban sources located in close proximity to more pristine mountainous areas to the west make the Colorado Front Range a unique area for studying atmospheric ammonia. The meteorology of the region, where heavy monsoon rains can be followed by rapid evaporation, can also impact surface-atmosphere partitioning of ammonia. As part of the Front Range Air Pollution and Photochemistry Éxperiment (FRAPPÉ), vertical profiles of ammonia were measured throughout the boundary layer aboard a moveable platform on the 300 m Boulder Atmospheric Observatory (BAO) tower. Changes in ammonia concentration and its vertical structure were driven not only by changes in wind direction and estimated source region, but also by fluctuations in surface and atmosphere water content. For example, large increases in atmospheric ammonia mixing ratios were observed following rain events. This may be explained by surface-atmosphere exchange of wet-deposited ammonia associated with rapid evaporation following the event, and likely impacts particle formation. This may also play a role in transport from ammonia-rich agricultural areas towards the mountainous regions to the west during periods of upslope flow. The vertical ammonia concentration gradients observed throughout the structured early morning boundary layer also provide insight into the possible causes of early morning spikes in ammonia - a phenomenon that has been well-documented in many other locations. A box model was used to assess the relative importance of surface emissions due to the evaporation of morning dew versus entrainment of ammonia-rich air from above the

  7. The host galaxies and narrow-line regions of four double-peaked [OIII] AGNs

    Energy Technology Data Exchange (ETDEWEB)

    Villforth, Carolin; Hamann, Fred [Department of Astronomy, University of Florida, 32611 Gainesville, FL (United States)

    2015-03-01

    Major gas-rich mergers of galaxies are expected to play an important role in triggering and fueling luminous active galactic nuclei (AGNs). The mechanism of AGN fueling during mergers, however, remains poorly understood. We present deep multi-band (u/r/z) imaging and long-slit spectroscopy of four double-peaked [OIII] emitting AGNs. This class of object is likely associated with either kiloparsec-separated binary AGNs or final stage major mergers, although AGNs with complex narrow-line regions (NLRs) are known contaminants. Such objects are of interest since they represent the onset of AGN activity during the merger process. Three of the four double-peaked [OIII] emitters studied have been confirmed as major mergers using near-infrared imaging and one is a confirmed X-ray binary AGN. All AGNs are luminous, radio-quiet to radio-intermediate, and have redshifts of 0.1regions showing considerable reddening, consistent with enhanced star formation. One source shows an offset between gas and stellar kinematics, consistent with either a bipolar flow or a counter-rotating gas disk. In all other sources, the ionized gas

  8. Quasar Rain: The Broad Emission Line Region as Condensations in the Warm Accretion Disk Wind

    Science.gov (United States)

    Elvis, Martin

    2017-09-01

    The origin of the broad emission line region (BELR) in quasars and active galactic nuclei is still unclear. I propose that condensations form in the warm, radiation-pressure-driven, accretion disk wind of quasars creating the BEL clouds and uniting them with the other two manifestations of cool (∼104 K) gas in quasars, the low ionization phase of the warm absorbers (WAs) and the clouds causing X-ray eclipses. The cool clouds will condense quickly (days to years), before the WA outflows reach escape velocity (which takes months to centuries). Cool clouds form in equilibrium with the warm phase of the wind because the rapidly varying X-ray quasar continuum changes the force multiplier, causing pressure waves to move gas into stable locations in pressure–temperature space. The narrow range of two-phase equilibrium densities may explain the (luminosity){}1/2 scaling of the BELR size, while the scaling of cloud formation timescales could produce the Baldwin effect. These dense clouds have force multipliers of order unity and so cannot be accelerated to escape velocity. They fall back on a dynamical timescale (months to centuries), producing an inflow that rains down toward the central black hole. As they soon move at Mach ∼10–100 with respect to the WA outflow, these “raindrops” will be rapidly destroyed within months. This rain of clouds may produce the elliptical BELR orbits implied by velocity-resolved reverberation mapping in some objects and can explain the opening angle and destruction timescale of the narrow “cometary” tails of the clouds seen in X-ray eclipse observations. Some consequences and challenges of this “quasar rain” model are presented, along with several avenues for theoretical investigation.

  9. Kinematics and structure of clumps in broad-line regions in active galactic nuclei

    Science.gov (United States)

    Ghayuri, Mohammad

    2016-10-01

    We use the Jeans equations for an ensemble of collisionless particles to describe the distribution of broad-line region (BLR) cloud in three classes: (A) non-disc (B) disc-wind (C) pure disc structure. We propose that clumpy structures in the brightest quasars belong to class A, fainter quasars and brighter Seyferts belong to class B, and dimmer Seyfert galaxies and all low-luminosity AGNs (LLAGNs) belong to class C. We derive the virial factor, f, for disc-like structures and find a negative correlation between the inclination angle, θ0, and f. We find similar behaviour for f as a function of the FWHM and σz, the z component of velocity dispersion. For different values of θ0 we find that 1.0 ≲ f ≲ 9.0 in type1 AGNs and 0.5 ≲ f ≲ 1.0 in type2 AGNs. Moreover we have 0.5 ≲ f ≲ 6.5 for different values of FWHM and 1.4 ≲ f ≲ 1.8 for different values of σz. We also find that f is relatively insensitive to the variations of bolometric luminosity and column density of each cloud and the range of variation of f is in order of 0.01. Considering wide range of f we see the use of average virial factor is not very safe. Therefore we propose AGN community to divide a sample into a few subsamples based on the value of θ0 and FWHM of members and calculate for each group separately to reduce uncertainty in black hole mass estimation.

  10. Constraining UV continuum slopes of active galactic nuclei with cloudy models of broad-line region extreme-ultraviolet emission lines

    Energy Technology Data Exchange (ETDEWEB)

    Moloney, Joshua [CASA, Department of Astrophysical and Planetary Sciences, University of Colorado, Boulder, CO 80309 (United States); Michael Shull, J., E-mail: joshua.moloney@colorado.edu, E-mail: michael.shull@colorado.edu [Also at Institute of Astronomy, University of Cambridge, Cambridge CB3 0HA, UK. (United Kingdom)

    2014-10-01

    Understanding the composition and structure of the broad-line region (BLR) of active galactic nuclei (AGNs) is important for answering many outstanding questions in supermassive black hole evolution, galaxy evolution, and ionization of the intergalactic medium. We used single-epoch UV spectra from the Cosmic Origins Spectrograph (COS) on the Hubble Space Telescope to measure EUV emission-line fluxes from four individual AGNs with 0.49 ≤ z ≤ 0.64, two AGNs with 0.32 ≤ z ≤ 0.40, and a composite of 159 AGNs. With the CLOUDY photoionization code, we calculated emission-line fluxes from BLR clouds with a range of density, hydrogen ionizing flux, and incident continuum spectral indices. The photoionization grids were fit to the observations using single-component and locally optimally emitting cloud (LOC) models. The LOC models provide good fits to the measured fluxes, while the single-component models do not. The UV spectral indices preferred by our LOC models are consistent with those measured from COS spectra. EUV emission lines such as N IV λ765, O II λ833, and O III λ834 originate primarily from gas with electron temperatures between 37,000 K and 55,000 K. This gas is found in BLR clouds with high hydrogen densities (n {sub H} ≥ 10{sup 12} cm{sup –3}) and hydrogen ionizing photon fluxes (Φ{sub H} ≥ 10{sup 22} cm{sup –2} s{sup –1}).

  11. Photon-dominated region modeling of the [C I], [C II], and CO Line Emission From A Boundary In The Taurus molecular cloud

    Energy Technology Data Exchange (ETDEWEB)

    Orr, Matthew E. [Physics and Astronomy Department, University of Southern California, Los Angeles, CA 90089 (United States); Pineda, Jorge L.; Goldsmith, Paul F. [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109-8099 (United States)

    2014-11-01

    We present [C I] and [C II] observations of a linear edge region in the Taurus molecular cloud, and model this region as a cylindrically symmetric photon-dominated region (PDR) exposed to a low-intensity UV radiation field. The sharp, long profile of the linear edge makes it an ideal case to test PDR models and determine cloud parameters. We compare observations of the [C I], {sup 3} P {sub 1} → {sup 3} P {sub 0} (492 GHz), [C I] {sup 3} P {sub 2} → {sup 3} P {sub 1} (809 GHz), and [C II] {sup 2} P {sub 3/2} → {sup 2} P {sub 1/2} (1900 GHz) transitions, as well as the lowest rotational transitions of {sup 12}CO and {sup 13}CO, with line intensities produced by the RATRAN radiative transfer code from the results of the Meudon PDR code. We constrain the density structure of the cloud by fitting a cylindrical density function to visual extinction data. We study the effects of variation of the FUV field, {sup 12}C/{sup 13}C isotopic abundance ratio, sulfur depletion, cosmic ray ionization rate, and inclination of the filament relative to the sky-plane on the chemical network of the PDR model and resulting line emission. We also consider the role of suprathermal chemistry and density inhomogeneities. We find good agreement between the model and observations, and that the integrated line intensities can be explained by a PDR model with an external FUV field of 0.05 G {sub 0}, a low ratio of {sup 12}C to {sup 13}C ∼43, a highly depleted sulfur abundance (by a factor of at least 50), a cosmic ray ionization rate (3-6) × 10{sup –17} s{sup –1}, and without significant effects from inclination, clumping or suprathermal chemistry.

  12. [The study of profile of hypersensitivity to pollen and fungal allergens in the Moscow region].

    Science.gov (United States)

    Akhapkina, I G; Krakhanenkova, S N; Dobronravova, E V; Shushpanova, E N

    2014-05-01

    The profile of hypersensitivity to pollen and fungal allergens is an important element of common pattern of immune diseases needed for development of effective pharmaceuticals. The purpose of the study was to analyze the rate of detection of combined forms of hypersensitivity to pollen and fungal allergens (pollen of birch, hazel, cocksfoot, wormwood, fungi A. alternata, C. herbarum, R. nigricans, P. notatum, C. albicans, A. fumigatus) in the Moscow region on the basis of data of scarification skin samples. The mono-sensibilization was established in 23.36% of all cases of hypersensitivity. At that, among leading allergens turned out A. alternata and cocksfoot pollen (6.54% and 4.67%), followed by allergens of wormwood pollen, P. notatum, R. nigricans, birch pollen and C. albicans (3.74%, 3.74%, 1.87%, 1.87% and 0.93% correspondingly). The polysensibilization was established in 51.40% of cases. Besides, the combined hypersensitivity to pollen allergens of plants (20.26%) and to pollen and fungal allergens (20.56%) occurred more frequently In the group of patients with polysensibilization predominated combined allergic reactions to pollen allergens and A. alternata allergens (36.36%). On the whole, most frequently occurred sensitization to allergens of birch, hazel, cocksfoot, wormwood and A. alternata allergen (76.14%, 69.32%, 57.95%, 55.68%, 39.77% and 56.82% correspondingly). In the Moscow region predominate combined forms of hypersensitivity to two and more pollen and fungal allergens. The polysensitization to pollen allergens and A. alternata allergen occurs more frequently.

  13. INTRAPRENEURIAL PROFILE AND ACTIONS OF ACCOUNTING COURSE ADMINISTRATORS IN THE WESTERN REGION OF PARANA

    Directory of Open Access Journals (Sweden)

    Maria José Carvalho de Souza Domingues

    2012-03-01

    Full Text Available This article aims to identify and analyze the intrapreneurial actions, profile, and characteristics of the administrators for undergraduate courses of Accounting Sciences in the western region of Paraná. Thus, the research question was formulated: What are the intrapreneurial characteristics and the main actions of the Accounting course adminis trators in the western region of Paraná?The method used was descriptive research in the form of a survey and, for data collection, a questionnaire, from Mastella (2005 and Dornelas (2003, adapted by Walter et al. (2007. Among the main results, it was found that the managers are men, mostly over 50 years of age, with the title of specialist or master, and whose principal tie is to the institution in which they operate. It was noted that most of the actions undertaken by the managers have demonstrated an internal bent, a fact that should be the object of reflection, once those actions considered of the greatest import by managers are often the least carried out. Therefore, little time dedicated to management, discrepancies between desired actions and those which are effectively carried out, and too much internal focus behind their actions are aspects which should be improved by the managers who were surveyed. All the respondents show intrapreneurial characteristics. There is a perceptible need for greater clarity in the dialogue between managers and their superiors for a greater alignment relative to the current performance of managers. It is also noted that issues such as reconciliation of teaching / management hours still requires improvement.

  14. Direct profiling of myelinated and demyelinated regions in mouse brain by imaging mass spectrometry

    Science.gov (United States)

    Ceuppens, Ruben; Dumont, Debora; van Brussel, Leen; van de Plas, Babs; Daniels, Ruth; Noben, Jean-Paul; Verhaert, Peter; van der Gucht, Estel; Robben, Johan; Clerens, Stefan; Arckens, Lutgarde

    2007-02-01

    One of the newly developed imaging mass spectrometry (IMS) technologies utilizes matrix-assisted laser desorption/ionization (MALDI) mass spectrometry to map proteins in thin tissue sections. In this study, we evaluated the power of MALDI IMS as we developed it in our (Bruker) MALDI TOF (Reflex IV) and TOF-TOF (Ultraflex II) systems to study myelin patterns in the mouse central nervous system under normal and pathological conditions. MALDI IMS was applied to assess myelin basic protein (MBP) isoform-specific profiles in different regions throughout the mouse brain. The distribution of ions of m/z 14,144 and 18,447 displayed a striking resemblance with white matter histology and were identified as MBP isoform 8 and 5, respectively. In addition, we demonstrated a significant reduction of the MBP-8 peak intensity upon MALDI IMS analysis of focal ethidium bromide-induced demyelinated brain areas. Our MS images were validated by immunohistochemistry using MBP antibodies. This study underscores the potential of MALDI IMS to study the contribution of MBP to demyelinating diseases.

  15. Photon-Dominated Region Modeling of the [C I],[C II], and CO Line Emission from a Boundary in the Taurus Molecular Cloud

    CERN Document Server

    Orr, Matthew; Goldsmith, Paul

    2014-01-01

    We present [Ci] and [Cii] observations of a linear edge region in the Taurus molecular cloud, and model this region as a cylindrically symmetric PDR exposed to a low-intensity UV radiation field. The sharp, long profile of the linear edge makes it an ideal case to test PDR models and determine cloud parameters. We compare observations of the [C i], 3P1 -> 3P0 (492 GHz), [C i] 3P2 -> 3P1 (809 GHz), and [Cii] 2P3/2 -> 2P1/2 (1900 GHz) transitions, as well as the lowest rotational transitions of 12CO and 13CO, with line intensities produced by the RATRAN radiative transfer code from the results of the Meudon PDR code. We constrain the density structure of the cloud by fitting a cylindrical density function to visual extinction data. We study the effects of variation of the FUV field, 12C/13C isotopic abundance ratio, sulfur depletion, cosmic ray ionization rate, and inclination of the filament relative to the sky-plane on the chemical network of the PDR model and resulting line emission. We also consider the rol...

  16. Line parameters including temperature dependences of air- and self-broadened line shapes of 12C16O2: 2.06-μm region

    Science.gov (United States)

    Benner, D. Chris; Devi, V. Malathy; Sung, Keeyoon; Brown, Linda R.; Miller, Charles E.; Payne, Vivienne H.; Drouin, Brian J.; Yu, Shanshan; Crawford, Timothy J.; Mantz, Arlan W.; Smith, Mary Ann H.; Gamache, Robert R.

    2016-08-01

    This study reports the results from analyzing a number of high resolution, high signal-to-noise ratio (S/N) spectra in the 2.06-μm spectral region for pure CO2 and mixtures of CO2 in dry air. A multispectrum nonlinear least squares curve fitting technique has been used to retrieve the various spectral line parameters. The dataset includes 27 spectra: ten pure CO2, two 99% 13C-enriched CO2 and fifteen spectra of mixtures of 12C-enriched CO2 in dry air. The spectra were recorded at various gas sample temperatures between 170 and 297 K. The absorption path lengths range from 0.347 to 49 m. The sample pressures for the pure CO2 spectra varied from 1.1 to 594 Torr; for the two 13CO2 spectra the pressures were ∼10 and 146 Torr. For the air-broadened spectra, the pressures of the gas mixtures varied between 200 and 711 Torr with CO2 volume mixing ratios ranging from 0.014% to 0.203%. The multispectrum fitting technique was applied to fit simultaneously all these spectra to retrieve consistent set of line positions, intensities, and line shape parameters including their temperature dependences; for this, the Voigt line shape was modified to include line mixing (via the relaxation matrix formalism) and quadratic speed dependence. The new results are compared to select published values, including recent ab initio calculations. These results are required to retrieve the column averaged dry air mole fraction (XCO2) from space-based observations, such as the Orbiting Carbon Observatory-2 (OCO-2) satellite mission that NASA launched in July 2014.

  17. Chromospheric polarimetry through multi-line observations of the 850 nm spectral region

    CERN Document Server

    Noda, C Quintero; Katsukawa, Y; Rodriguez, J de la Cruz; Carlsson, M; Anan, T; Oba, T; Ichimoto, K; Suematsu, Y

    2016-01-01

    Future solar missions and ground-based telescopes aim to understand the magnetism of the solar chromosphere. We performed a supporting study in Quintero Noda et al. (2016) focused on the infrared Ca II 8542 A line and we concluded that is one of the best candidates because it is sensitive to a large range of atmospheric heights, from the photosphere to the middle chromosphere. However, we believe that it is worth to try improving the results produced by this line observing additional spectral lines. In that regard, we examined the neighbour solar spectrum looking for spectral lines that could increase the sensitivity to the atmospheric parameters. Interestingly, we discovered several photospheric lines that greatly improve the photospheric sensitivity to the magnetic field vector. Moreover, they are located close to a second chromospheric line that also belongs to the Ca II infrared triplet, i.e. the Ca II 8498 A line, and enhances the sensitivity to the atmospheric parameters at chromospheric layers. We conc...

  18. TIGER/Line Shapefile, 2016, state, Alaska, Current Alaska Native Regional Corporation (ANRC) State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  19. An assessment of the Living Laboratory approach for collaborative innovation and design of the Regional Spatial Profiler

    CSIR Research Space (South Africa)

    Mlangeni, P

    2012-10-01

    Full Text Available The premise of this poster is to highlight the Living Lab approach adopted for the development of the Regional Spatial Profiler (RSP) component of the Integrated Planning and Development Modelling (IPDM) project. The RSP is showcased in this poster...

  20. Profile distribution of polycyclic aromatic hydrocarbons in soils of drained peatlands after wildfires (Moscow region, Russia)

    Science.gov (United States)

    Tsibart, Anna; Gennadiev, Alexander; Koshovskii, Timur; Kovach, Roman

    2014-05-01

    Polycyclic aromatic compounds (PAHs) are formed in different natural and anthropogenic processes and could be found in many landscape components. These compounds are carcinogenic and belong to the group of persistent organic pollutants. The anthropogenic sources of PAHs are well-studied, but insufficient data are available on the hightemperature production of PAHs in natural processes. For example, natural fires are frequently related to the PAHs sources in landscapes, but very little factual data are on this topic. The soils of drained peatlands affected by catastrophic wildfires of 2010 and 2002 were studied in the Eastern part of Moscow Region (Russia). A total of 14 profiles of histosols and histic podsols were investigated. These series included soils of plots subjected to fires of different intensities and age, as well as soils of the background plots. Soil samples were taken from genetic horizons and from every 10 cm. The samples were analyzed for the contents of 14 prevailing individual compounds: fluorene, naphthalene, phenanthrene, chrysene, pyrene, anthracene, tetraphene, benz[a]pyrene, benzo[ghi]perylene, benzo[e]pyrene, coronene, dibenztiophene, triphenilene, benz(k)fluorantene. Morfological properties of soils after wildfires on drained peatlands were changed dramatically, the horizons of ash and char instead of organic layers were formed. These new horizons differ in the capability of PAHs accumulation. The char horizons have the highest concentrations of PAHs - up to 300 ng/g because of incomplete burning of organic matter in this sites, and the ash horizons, where the complete burning occured, contain only 10 ng/g PAHs. The highest concentrations of PAHs in soil profiles were detected after recent fires, and in cases of thick peat layers. After the combustion of peat chrysene, benz[a]pyrene, benz[e]pyrene, benzo[ghi]perylene, benz(k)fluorantene and tetraphene accumulated in soils. This is mainly the group of 4-6-nuclear compounds. The formation of