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Sample records for reflect inherent differences

  1. Inherent Difference in Saliency for Generators with Different PM Materials

    Directory of Open Access Journals (Sweden)

    Sandra Eriksson

    2014-01-01

    Full Text Available The inherent differences between salient and nonsalient electrical machines are evaluated for two permanent magnet generators with different configurations. The neodymium based (NdFeB permanent magnets (PMs in a generator are substituted with ferrite magnets and the characteristics of the NdFeB generator and the ferrite generator are compared through FEM simulations. The NdFeB generator is a nonsalient generator, whereas the ferrite machine is a salient-pole generator, with small saliency. The two generators have almost identical properties at rated load operation. However, at overload the behaviour differs between the two generators. The salient-pole, ferrite generator has lower maximum torque than the NdFeB generator and a larger voltage drop at high current. It is concluded that, for applications where overload capability is important, saliency must be considered and the generator design adapted according to the behaviour at overload operation. Furthermore, if the maximum torque is the design criteria, additional PM mass will be required for the salient-pole machine.

  2. Remote sensing reflectance and inherent optical properties of oceanic waters derived from above-water measurements

    Science.gov (United States)

    Lee, Zhongping; Carder, Kendall L.; Steward, Robert G.; Peacock, Thomas G.; Davis, Curtiss O.; Mueller, James L.

    1997-02-01

    Remote-sensing reflectance and inherent optical properties of oceanic properties of oceanic waters are important parameters for ocean optics. Due to surface reflectance, Rrs or water-leaving radiance is difficult to measure from above the surface. It usually is derived by correcting for the reflected skylight in the measured above-water upwelling radiance using a theoretical Fresnel reflectance value. As it is difficult to determine the reflected skylight, there are errors in the Q and E derived Rrs, and the errors may get bigger for high chl_a coastal waters. For better correction of the reflected skylight,w e propose the following derivation procedure: partition the skylight into Rayleigh and aerosol contributions, remove the Rayleigh contribution using the Fresnel reflectance, and correct the aerosol contribution using an optimization algorithm. During the process, Rrs and in-water inherent optical properties are derived at the same time. For measurements of 45 sites made in the Gulf of Mexico and Arabian Sea with chl_a concentrations ranging from 0.07 to 49 mg/m3, the derived Rrs and inherent optical property values were compared with those from in-water measurements. These results indicate that for the waters studied, the proposed algorithm performs quite well in deriving Rrs and in- water inherent optical properties from above-surface measurements for clear and turbid waters.

  3. Inherent aerobic capacity-dependent differences in breast carcinogenesis.

    Science.gov (United States)

    Thompson, Henry J; Jones, Lee W; Koch, Lauren G; Britton, Steven L; Neil, Elizabeth S; McGinley, John N

    2017-09-01

    Although regular physical activity is associated with improvement in aerobic capacity and lower breast cancer risk, there are heritable sets of traits that affect improvement in aerobic capacity in response to physical activity. Although aerobic capacity segregates risk for a number of chronic diseases, the effect of the heritable component on cancer risk has not been evaluated. Therefore, we investigated breast carcinogenesis in rodent models of heritable fitness in the absence of induced physical activity. Female offspring of N:NIH rats selectively bred for low (LIAC) or high (HIAC) inherent aerobic capacity were injected intraperitoneally with 1-methyl-1-nitrosurea (70 mg/kg body wt). At study termination 33 weeks post-carcinogen, cancer incidence (14.0 versus 47.3%; P < 0.001) and multiplicity (0.18 versus 0.85 cancers per rat; P < 0.0001) were significantly decreased in HIAC versus LIAC rats, respectively. HIAC had smaller visceral and subcutaneous body fat depots than LIAC and activity of two proteins that regulated the mammalian target of rapamycin, protein kinase B (Akt), and adenosine monophosphate-activated protein kinase were suppressed and activated, respectively, in HIAC. Although many factors distinguish between HIAC and LIAC, it appears that the protective effect of HIAC against breast carcinogenesis is mediated, at least in part, via alterations in core metabolic signaling pathways deregulated in the majority of human breast cancers. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  4. Inherent characteristics of sawtooth cycles can explain different glacial periodicities

    NARCIS (Netherlands)

    Omta, A.W.; Kooi, B.W.; van Voorn, G.A.K.; Rickaby, R.E.M; Follows, M.J.

    2016-01-01

    At the Mid-Pleistocene Transition about 1 Ma, the dominant periodicity of the glacial-interglacial cycles shifted from ~40 to ~100 kyr. Here, we use a previously developed mathematical model to investigate the possible dynamical origin of these different periodicities. The model has two variables,

  5. Inherent characteristics of sawtooth cycles can explain different glacial periodicities

    NARCIS (Netherlands)

    Omta, Anne Willem; Kooi, Bob W.; Voorn, van G.A.K.; Rickaby, Rosalind E.M.; Follows, Michael J.

    2016-01-01

    At the Mid-Pleistocene Transition about 1 Ma, the dominant periodicity of the glacial-interglacial cycles shifted from ~40 to ~100 kyr. Here, we use a previously developed mathematical model to investigate the possible dynamical origin of these different periodicities. The model has two

  6. Chimera Type Behavior in Nonlocal Coupling System with Two Different Inherent Frequencies

    Science.gov (United States)

    Lin, Larry; Li, Ping-Cheng; Tseng, Hseng-Che

    2014-03-01

    From the research of Kuramoto and Strogatz, arrays of identical oscillators can display a remarkable pattern, named chimera state, in which phase-locked oscillators coexist with drifting ones in nonlocal coupling oscillator system. We consider further in this study, two groups of oscillators with different inherent frequencies and arrange them in a ring. When the difference of the inherent frequencies is within some specific parameter range, oscillators of nonlocal coupling system show two distinct chimera states. When the parameter value exceeds some threshold value, two chimera states disappear. They show different features. The statistical dynamic behavior of the system can be described by Kuramoto theory.

  7. Inherent optical properties and remote sensing reflectance of Pomeranian lakes (Poland

    Directory of Open Access Journals (Sweden)

    Dariusz Ficek

    2012-11-01

    Full Text Available This paper describes the results of comprehensive empirical studies of theinherent optical properties (IOPs, the remote sensing reflectance Rrs(λ andthe contents of the principal optically active components (OAC i.e. coloureddissolved organic matter (CDOM, suspended particulate matter (SPM andchlorophyll a, in the waters of 15 lakes in Polish Pomerania in 2007-2010.It presents numerous spectra of the total absorption a(λ andscattering b(λ ≈ bp(λ of light in the visibleband (400-700 nm for surface waters, and separately, spectra of absorptionby CDOM aCDOM(λ and spectra of the mass-specificcoefficients of absorption ap*(SPM(λ and scatteringbp*(SPM(λ by SPM. The properties of these lake waters are highly diverse, but all of them can beclassified as Case 2 waters (according to the optical classification by Morel& Prieur 1977 and they all have a relatively high OAC content. The lakeswere conventionally divided into three types: Type I lakes have the lowestOAC concentrations (chlorophyll concentration Ca = (8.76 ± 7.4 mg m-3 and CDOM absorption coefficientsaCDOM(440 = (0.57 ± 0.22 m-1 (i.e. mean and standarddeviation, and optical properties (including spectra of Rrs(λresembling those of Baltic waters. Type II waters have exceptionally highcontents of CDOM (aCDOM(440 = (15.37 ± 1.54 m-1,and hence appear brown in daylight and have very low reflectancesRrs(λ (of the order of 0.001 sr-1. Type III waters arehighly eutrophic and contain large amounts of suspended matter, includingphytoplankton ((CSPM = (47.0 ± 39.4 g m-3,Ca = (86.6 ± 61.5 mg m-3; aCDOM(440 = (2.77 ± 0.86 m-1. Hence the reflectances Rrs(λof these type of waters are on average one order of magnitude higher thanthose of the other natural waters, reaching maximum values of 0.03 sr-1in λ bands 560-580 nm and 690-720 nm (see Ficek et al. 2011. Thearticle provides a number of empirical formulas approximating therelationships between the properties of these lake waters.

  8. Generating millimeter-wave Bessel beam with orbital angular momentum using reflective-type metasurface inherently integrated with source

    Science.gov (United States)

    Shen, Yizhu; Yang, Jiawei; Meng, Hongfu; Dou, Wenbin; Hu, Sanming

    2018-04-01

    Metasurfaces, orbital angular momenta (OAM), and non-diffractive Bessel beams have been attracting worldwide research. Combining the benefits of these three promising techniques, this paper proposes a metasurface-based reflective-type approach to generate a first-order Bessel beam carrying OAM. To validate this approach, a millimeter-wave metasurface is analyzed, designed, fabricated, and measured. Experimental results agree well with simulation. Moreover, this reflective-type metasurface, generating a Bessel beam with OAM, is inherently integrated with a planar feeding source in the same single-layer printed circuit board. Therefore, the proposed design features low profile, low cost, easy integration with front-end active circuits, and no alignment error between the feeding source and the metasurface.

  9. [Differences of inherent optical properties of inland lake water body in typical seasons].

    Science.gov (United States)

    Sun, De-Yong; Li, Yun-Mei; Wang, Qiao; Le, Cheng-Fen; Huang, Chang-Chun; Wang, Li-Zhen

    2008-05-01

    Inherent optical property is one of the important properties of water body, which lays the foundation for the establishment of water color analytical models. By using quantity filter technology (QFT) and BB9 backscattering meter, the absorption coefficients of chromophoric dissolved organic matter (CDOM) and total suspended matters (TSM) and the backscattering coefficient of TSM in the water body at Meiliang Bay of Taihu Lake were measured in summer and winter. Based on the spectral comparison of the absorption and backscattering coefficients, their differences between the two seasons were demonstrated, and the reasons that caused these differences were also explored in the context of their relations to the changes in water quality. Consequently, water environment condition could be revealed by using the inherent optical property. The relationship between the backscattering coefficient and the TSM concentration was established, which could provide supporting coefficients to the analytical models to be developed.

  10. Inherent wettability of different rock surfaces at nanoscale: a theoretical study

    Science.gov (United States)

    Chang, Xiao; Xue, Qingzhong; Li, Xiaofang; Zhang, Jianqiang; Zhu, Lei; He, Daliang; Zheng, Haixia; Lu, Shuangfang; Liu, Zilong

    2018-03-01

    Investigating the inherent wettability of rock surfaces at nanoscale is of great importance in ore floatation and oil recovery field. Using molecular dynamics simulations, we systematically study the wetting behavior of water on different rock surfaces (silica, calcite, gypsum, halite and graphite) at nanoscale. It is demonstrated that the inherent rock wettability follows the order of gypsum > calcite > halite > silica > graphite. Remarkably, we also manifest that the polarity of oil molecules can affect the water contact angles on silica surface. For example, the water contact angles on silica surface in hexane, dodecane, thiophene and toluene are 58 ± 2°, 63 ± 3°, 90 ± 1°, 118 ± 1°, respectively. Furthermore, we investigate the wetting behavior of water on heterogeneous rock surfaces and find that water molecules can move from hydrophobic surface to hydrophilic surface.

  11. Evaluation of different in vitro assays of inherent sensitivity as predictors of radiotherapy response

    International Nuclear Information System (INIS)

    Schwartz, J.L.; Chicago Univ., IL; Beckett, M.A.; Mustafi, R.; Weichselbaum, R.R.; Vaughan, A.T.M.

    1991-01-01

    The inherent sensitivity of cells within a tumor plays an important role in the response of the tumor to radiotherapy. Clonogenic assays show that cells established from in-field radiotherapy failures are significantly more resistant to radiation than cell lines established from pre-treatment samples. Clonogenic assays fail to predict tumor response to radiotherapy, however. The failure might be due to the small sample size in this study, or the complicating factors of staging, surgery, and chemotherapy, and/or in vivo selection by radiotherapy for resistant tumor cells. In vitro selection for resistant cell lines does not appear to be a complicating factor. Nonclonogenic assays such as those that measure DNA strand break rejoining rates (filter elution, pulse-field gel electrophoresis) or chromosome structure (flow cytometric analysis) show promise as alternative rapid assays of radiation sensitivity and possibly tumor response. 16 refs., 2 figs

  12. Obesity associated disease risk: the role of inherent differences and location of adipose depots.

    Science.gov (United States)

    Hill, Jessica H; Solt, Claudia; Foster, Michelle T

    2018-03-16

    Obesity and associated metabolic co-morbidities are a worldwide public health problem. Negative health outcomes associated with obesity, however, do not arise from excessive adiposity alone. Rather, deleterious outcomes of adipose tissue accumulation are a result of how adipocytes are distributed to individual regions in the body. Due to our increased understanding of the dynamic relationship that exists between specific adipose depots and disease risk, an accurate characterization of total body adiposity as well as location is required to properly evaluate a population's disease risk. Specifically, distinctive tissue depots within the body include the lower body, upper body and abdominal (deep and superficial) subcutaneous regions, as well as visceral (mesenteric and omental) regions. Upper body and visceral adipose tissues are highly associated with metabolic dysfunction and chronic disease development, whereas lower body gluteofemoral subcutaneous adipose tissue imparts protection against diet-induced metabolic derangement. Each adipose depot functions distinctly as an endocrine organ hence it has a different level of impact on health outcomes. Effluent from adipose tissue can modulate the functions of other tissues, whilst receiving differential communication from the rest of the body via central nervous system innervation, metabolites and other signaling molecules. More so, adipose depots contain a diverse reservoir of tissue-resident immune cells that play an integral part in both maintaining tissue homeostasis, as well as propagating metabolically-induced inflammation. Overall, the conceptualization of obesity and associated risks needs updating to reflect the complexities of obesity. We review adipose tissue characteristics that are linked to deleterious or beneficial adipose tissue distributions.

  13. Inherently safe reactors

    International Nuclear Information System (INIS)

    Maartensson, Anders

    1992-01-01

    A rethinking of nuclear reactor safety has created proposals for new designs based on inherent and passive safety principles. Diverging interpretations of these concepts can be found. This article reviews the key features of proposed advanced power reactors. An evaluation is made of the degree of inherent safety for four different designs: the AP-600, the PIUS, the MHTGR and the PRISM. The inherent hazards of today's most common reactor principles are used as reference for the evaluation. It is concluded that claims for the new designs being inherently, naturally or passively safe are not substantiated by experience. (author)

  14. Sex differences in the developing brain as a source of inherent risk.

    Science.gov (United States)

    McCarthy, Margaret M

    2016-12-01

    Brain development diverges in males and females in response to androgen production by the fetal testis. This sexual differentiation of the brain occurs during a sensitive window and induces enduring neuroanatomical and physiological changes that profoundly impact behavior. What we know about the contribution of sex chromosomes is still emerging, highlighting the need to integrate multiple factors into understanding sex differences, including the importance of context. The cellular mechanisms are best modeled in rodents and have provided both unifying principles and surprising specifics. Markedly distinct signaling pathways direct differentiation in specific brain regions, resulting in mosaicism of relative maleness, femaleness, and sameness through-out the brain, while canalization both exaggerates and constrains sex differences. Non-neuronal cells and inflammatory mediators are found in greater number and at higher levels in parts of male brains. This higher baseline of inflammation is speculated to increase male vulnerability to developmental neuropsychiatric disorders that are triggered by inflammation.

  15. Inherent structure features of beryllium and their influence on the performance polycrystalline metal under different conditions

    Energy Technology Data Exchange (ETDEWEB)

    Khomutov, A.M.; Mikhailov, V.S.; Pronin, V.N.; Pakhomov, Ya.D. [State Scientific Center of Russian Federation `A.A. Bochvar All-Russia Research Inst. of Inorganic Materials (VNIINM)`, Moscow (Russian Federation)

    1998-01-01

    The anisotropy of physical properties of beryllium single crystals resulting from covalent bonds in crystal lattice leads to significant residual thermal microstresses (RTM) in the polycrystalline metal. It is demonstrated experimentally that there is a simple linear dependence between the magnitude of RTM and the ultimate tensile strength. The factors controlling RTM are analysed and in the framework of powder metallurgy process the technological methods of producing beryllium with the needed properties are recommended. Primarily it is necessary to control the quantity and extent of dispersity of intergranular oxide inclusions and mean grain size in combination with the high degree of macro- and microhomogenity of the structure. The requirements to beryllium microstructure for different operating conditions including neutron fluxes and transient temperature fields are formulated. In the framework of the concept under development one can explain formerly not fully understandable effects, which are characteristic of polycrystalline beryllium such as unexpected Petch-Stro curve, the role of twinning etc., and predict new ones. In particular, it can be possible to expect the growth of ductility of high strength beryllium grades as neutron irradiated. (author)

  16. Neurons derived from different brain regions are inherently different in vitro: a novel multiregional brain-on-a-chip.

    Science.gov (United States)

    Dauth, Stephanie; Maoz, Ben M; Sheehy, Sean P; Hemphill, Matthew A; Murty, Tara; Macedonia, Mary Kate; Greer, Angie M; Budnik, Bogdan; Parker, Kevin Kit

    2017-03-01

    Brain in vitro models are critically important to developing our understanding of basic nervous system cellular physiology, potential neurotoxic effects of chemicals, and specific cellular mechanisms of many disease states. In this study, we sought to address key shortcomings of current brain in vitro models: the scarcity of comparative data for cells originating from distinct brain regions and the lack of multiregional brain in vitro models. We demonstrated that rat neurons from different brain regions exhibit unique profiles regarding their cell composition, protein expression, metabolism, and electrical activity in vitro. In vivo, the brain is unique in its structural and functional organization, and the interactions and communication between different brain areas are essential components of proper brain function. This fact and the observation that neurons from different areas of the brain exhibit unique behaviors in vitro underline the importance of establishing multiregional brain in vitro models. Therefore, we here developed a multiregional brain-on-a-chip and observed a reduction of overall firing activity, as well as altered amounts of astrocytes and specific neuronal cell types compared with separately cultured neurons. Furthermore, this multiregional model was used to study the effects of phencyclidine, a drug known to induce schizophrenia-like symptoms in vivo, on individual brain areas separately while monitoring downstream effects on interconnected regions. Overall, this work provides a comparison of cells from different brain regions in vitro and introduces a multiregional brain-on-a-chip that enables the development of unique disease models incorporating essential in vivo features. NEW & NOTEWORTHY Due to the scarcity of comparative data for cells from different brain regions in vitro, we demonstrated that neurons isolated from distinct brain areas exhibit unique behaviors in vitro. Moreover, in vivo proper brain function is dependent on the

  17. Audible reflection density for different late reflection criteria in rooms

    DEFF Research Database (Denmark)

    Krueger, Donata; Jeong, Cheol-Ho; Brunskog, Jonas

    2012-01-01

    For reasonably accurate but practical auralizations, some simplifications and approximations are needed. The main issue in the present investigation is that the reflection density of a room impulse response, in theory, increases so fast as a quadratic function of the elapsed time, even assuming...

  18. Gender differences in multitasking reflect spatial ability.

    Science.gov (United States)

    Mäntylä, Timo

    2013-04-01

    Demands involving the scheduling and interleaving of multiple activities have become increasingly prevalent, especially for women in both their paid and unpaid work hours. Despite the ubiquity of everyday requirements to multitask, individual and gender-related differences in multitasking have gained minimal attention in past research. In two experiments, participants completed a multitasking session with four gender-fair monitoring tasks and separate tasks measuring executive functioning (working memory updating) and spatial ability (mental rotation). In both experiments, males outperformed females in monitoring accuracy. Individual differences in executive functioning and spatial ability were independent predictors of monitoring accuracy, but only spatial ability mediated gender differences in multitasking. Menstrual changes accentuated these effects, such that gender differences in multitasking (and spatial ability) were eliminated between males and females who were in the menstrual phase of the menstrual cycle but not between males and females who were in the luteal phase. These findings suggest that multitasking involves spatiotemporal task coordination and that gender differences in multiple-task performance reflect differences in spatial ability.

  19. Reflections on Supervision and Culture: What Difference Does Difference Make?

    Science.gov (United States)

    Acker, Sandra

    2011-01-01

    For this commentary, the author went back and read most of her own writings on graduate education. Having only just retired but still working with supervisees and doing research, she reflects on supervision and culture. She has four questions for authors and readers: (1) What is supervision?; (2) What are the implications of "sameness" and…

  20. No benefits of ultrafractionation in two head-and-neck cancer cell lines with different inherent radiosensitivity

    International Nuclear Information System (INIS)

    Boehringer-Wyss, Nicole; Clarkson, Stuart G.; Allal, Abdelkarim S.

    2002-01-01

    Purpose: To assess if ultrafractionation is applicable in the context of an unknown hyperradiosensitivity (HRS) status, we studied the survival and repair capacity of two tumor cell lines after irradiation with two different dose/fractionation schedules that can be used in a clinical setting. Methods and Materials: Squamous cell carcinoma cell lines SCC-3 (radioresistant) and SCC-6 (radiosensitive) were used. Survival was studied by clonogenic assay after multiple fractions of 0.5 Gy (2 fractions/day, 6-h interval) and 2 Gy (1 fraction/day) for a total dose of 8 Gy of γ-rays. The capacity to repair single-strand and double-strand breaks (SSB, DSB) was assessed by comet assay. The messenger RNA (mRNA) levels of DNA-dependent protein kinase (PK) components were analyzed by RNase protection and real-time polymerase chain reaction (PCR). Results: In both cell lines, no apparent difference was noted between the two fractionation protocols. In particular for SCC-3, the mean surviving fraction tended to be lower after 2 Gy than after 0.5 Gy fractions. In SCC-3 and SCC-6 no significant difference was observed in the repair capacity of SSB and DSB after exposure to single doses of 0.5 Gy or 2 Gy. After exposure to the same single doses, the mRNA levels of DNA-PK catalytic subunit (PKcs), Ku 70, and Ku 80 were similar. Conclusions: Our data do not support the concept of ultrafractionation, at least when using fractions of 0.5 Gy in the cell lines studied. This suggests that methods for testing HRS status in individual tumors need to be developed before the relevance of ultrafractionation can be investigated in the clinic

  1. Angular dependance of spectral reflection for different materials

    Science.gov (United States)

    Kiefer, Pascal M.

    2017-10-01

    Parameters like the sun angle as well as the measurement angle mostly are not taken into account when simulating because their influence on the reflectivity is weak. Therefore the impact of a changing measurement and illumination angle on the reflectivity is investigated. Furthermore the impact of humidity and chlorophyll in the scenery is studied by analyzing reflectance spectra of different vegetative background areas. It is shown that the measurement as well as the illumination angle has an important influence on the absolute reflection values which raises the importance of measurements of the bidirectional reflectance distribution function (BRDF).

  2. In favor of general probability distributions: lateral prefrontal and insular cortices respond to stimulus inherent, but irrelevant differences.

    Science.gov (United States)

    Mestres-Missé, Anna; Trampel, Robert; Turner, Robert; Kotz, Sonja A

    2016-04-01

    A key aspect of optimal behavior is the ability to predict what will come next. To achieve this, we must have a fairly good idea of the probability of occurrence of possible outcomes. This is based both on prior knowledge about a particular or similar situation and on immediately relevant new information. One question that arises is: when considering converging prior probability and external evidence, is the most probable outcome selected or does the brain represent degrees of uncertainty, even highly improbable ones? Using functional magnetic resonance imaging, the current study explored these possibilities by contrasting words that differ in their probability of occurrence, namely, unbalanced ambiguous words and unambiguous words. Unbalanced ambiguous words have a strong frequency-based bias towards one meaning, while unambiguous words have only one meaning. The current results reveal larger activation in lateral prefrontal and insular cortices in response to dominant ambiguous compared to unambiguous words even when prior and contextual information biases one interpretation only. These results suggest a probability distribution, whereby all outcomes and their associated probabilities of occurrence--even if very low--are represented and maintained.

  3. Operation: Inherent Resolve

    DEFF Research Database (Denmark)

    Cramer-Larsen, Lars

    2015-01-01

    Kapitlet giver læseren indsigt i den internationale koalitions engagement mod IS igennem Operaton Inherent Resolve; herunder koalitionens strategi i forhold til IS strategi, ligesom det belyser kampagnens legalitet og folkeretlige grundlag, ligesom det giver et bud på overvejelser om kampagnens...

  4. Inherent/passive safety for fusion

    International Nuclear Information System (INIS)

    Piet, S.J.

    1986-06-01

    The concept of inherent or passive passive safety for fusion energy is explored, defined, and partially quantified. Four levels of safety assurance are defined, which range from true inherent safety to passive safety to protection via active engineered safeguard systems. Fusion has the clear potential for achieving inherent or passive safety, which should be an objective of fusion research and design. Proper material choice might lead to both inherent safety and high mass power density, improving both safety and economics. When inherent safety is accomplished, fusion will be well on the way to achieving its ultimate potential and to be truly different and superior

  5. Measurement of inherent optical properties in the Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Suresh, T.; Desa, E.; Kurian, J.; Mascarenhas, A.A.M.Q.

    Inherent optical properties, absorption and began attenuation were measured in situ using a reflective tube absorption meter at nint wavelength, 412, 440, 488, 510, 555, 630, 650, 676 and 715 nm, in the Arabian Sea during March. Since inherent...

  6. Vowel Inherent Spectral Change

    CERN Document Server

    Assmann, Peter

    2013-01-01

    It has been traditional in phonetic research to characterize monophthongs using a set of static formant frequencies, i.e., formant frequencies taken from a single time-point in the vowel or averaged over the time-course of the vowel. However, over the last twenty years a growing body of research has demonstrated that, at least for a number of dialects of North American English, vowels which are traditionally described as monophthongs often have substantial spectral change. Vowel Inherent Spectral Change has been observed in speakers’ productions, and has also been found to have a substantial effect on listeners’ perception. In terms of acoustics, the traditional categorical distinction between monophthongs and diphthongs can be replaced by a gradient description of dynamic spectral patterns. This book includes chapters addressing various aspects of vowel inherent spectral change (VISC), including theoretical and experimental studies of the perceptually relevant aspects of VISC, the relationship between ar...

  7. Leaf waxes of slow-growing alpine and fast-growing lowland Poa species: inherent differences and responses to UV-B radiation

    International Nuclear Information System (INIS)

    Pilon, J.J.; Lambers, H.; Baas, W.; Tosserams, M.; Rozema, J.; Atkin, O.K.

    1999-01-01

    We investigated whether alpine and lowland Poa species exhibit inherent differences in leaf cuticular waxes, leaf UV absorbing compounds and/or growth responses to UV-B treatment. All plants were grown hydroponically in a growth cabinet (constant 20°; 14 hr photoperiod; 520 μmol photons m −2 s −1 PAR). Two alpine (P. fawcettiae and P. costiniana), one sub-alpine (P. alpina) and three temperate lowland species (P. pratensis, P. compressa and P. trivialis) were grown under conditions without UV radiation for 36 days. In a subsequent experiment, four Poa species (P. costiniana, P. alpina, P. compressa and P. trivialis) were also exposed for 21 days to UV-B/(UV-A) radiation ('UV-B treatment') that resulted in daily UV-B radiation of 7.5 kJ m −2 day −1 , with control plants being grown without UV-B ('UV-A control treatment'). All treatments were carried out in the same growth cabinet. There was no altitudinal trend regarding wax concentrations per unit leaf area, when the six species grown under UV-less conditions, were compared at similar developmental stage (20–30 g shoot fresh mass). However, large differences in cuticular wax chemical composition were observed between the alpine and lowland species grown under UV-less conditions. For example, a single primary alcohol was present in the waxes of the lowland and sub-alpine species (C 26 H 53 OH), but was virtually absent in the alpine species. Although alkanes were present in all six species (primarily C 29 H 60 and C 31 H 64 ), the proportion of total wax present as alkanes was highest in the alpine species. Aldehydes were only present in the waxes of the alpine species. Conversely, substantial amounts of triterpenoids were mainly present in the three lowland species (squalene and lupeol were the dominant forms). The proportion of total wax present as long-chain esters (LCE-s) was similar in all six species grown in the absence of UV radiation. Acetates were observed only in the wax of

  8. Detection limit calculations for different total reflection techniques

    International Nuclear Information System (INIS)

    Sanchez, H.J.

    2000-01-01

    In this work, theoretical calculations of detection limits for different total-reflection techniques are presented.. Calculations include grazing incidence (TXRF) and gracing exit (GEXRF) conditions. These calculations are compared with detection limits obtained for conventional x-ray fluorescence (XRF). In order to compute detection limits the Shiraiwa and Fujino's model to calculate x-ray fluorescence intensities was used. This model made certain assumptions and approximations to achieve the calculations, specially in the case of the geometrical conditions of the sample, and the incident and takeoff beams. Nevertheless the calculated data of detection limits for conventional XRF and total-reflection XRF show a good agreement with previous results. The model proposed here allows to analyze the different sources of background and the influence of the excitation geometry, which contribute to the understanding of the physical processes involved in the XRF analysis by total reflection. Finally, a comparison between detection limits in total-reflection analysis at grazing incidence and at grazing exit is carried out. Here a good agreement with the theoretical predictions of the reversibility principle is found, showing that detection limits are similar for both techniques. (author)

  9. How Do Pre-Service Teachers' Reflective Processes Differ in Relation to Different Contexts?

    Science.gov (United States)

    Kaasila, Raimo; Lauriala, Anneli

    2012-01-01

    Reflective practice represents a central theme in teacher education. The focus of this study is to look at pre-service teachers' reflection processes and their breadth and depth in four different contexts. Our research data consist of 53 pre-service teachers' mathematics portfolios, from which three were selected for closer scrutiny. The chosen…

  10. Robust reflective ghost imaging against different partially polarized thermal light

    Science.gov (United States)

    Li, Hong-Guo; Wang, Yan; Zhang, Rui-Xue; Zhang, De-Jian; Liu, Hong-Chao; Li, Zong-Guo; Xiong, Jun

    2018-03-01

    We theoretically study the influence of degree of polarization (DOP) of thermal light on the contrast-to-noise ratio (CNR) of the reflective ghost imaging (RGI), which is a novel and indirect imaging modality. An expression for the CNR of RGI with partially polarized thermal light is carefully derived, which suggests a weak dependence of CNR on the DOP, especially when the ratio of the object size to the speckle size of thermal light has a large value. Different from conventional imaging approaches, our work reveals that RGI is much more robust against the DOP of the light source, which thereby has advantages in practical applications, such as remote sensing.

  11. Micro reflectance difference techniques: Optical probes for surface exploration

    Energy Technology Data Exchange (ETDEWEB)

    Lastras-Martinez, L.F.; Del Pozo-Zamudio, O.; Herrera-Jasso, R.; Ulloa-Castillo, N.A.; Balderas-Navarro, R.E.; Ortega-Gallegos, J.; Lastras-Martinez, A. [Instituto de Investigacion en Comunicacion Optica, Universidad Autonoma de San Luis Potosi, Alvaro Obregon 64, 78000 San Luis Potosi, S.L.P. (Mexico)

    2012-06-15

    Micro reflectance difference spectroscopy ({mu}-RDS) is a promising tool for the in-situ and ex-situ characterization of semiconductors surfaces and interfaces. We discuss and compare two different approaches used to measure {mu}-RD spectra. One is based on a charge-coupled device (CCD) camera, while the other uses a laser and a XY translation stage. To show the performance of these systems, we have measured surface optical anisotropies of GaSb(001) sample on which anisotropic strains have been generated by preferential mechanical polishing along [110] and [1 anti 10] directions. The spectrometers are complementary and the selection of one of them depends on the sample to be investigated and on experimental conditions. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  12. Leaders' smiles reflect cultural differences in ideal affect.

    Science.gov (United States)

    Tsai, Jeanne L; Ang, Jen Ying Zhen; Blevins, Elizabeth; Goernandt, Julia; Fung, Helene H; Jiang, Da; Elliott, Julian; Kölzer, Anna; Uchida, Yukiko; Lee, Yi-Chen; Lin, Yicheng; Zhang, Xiulan; Govindama, Yolande; Haddouk, Lise

    2016-03-01

    Cultures differ in the emotions they teach their members to value ("ideal affect"). We conducted 3 studies to examine whether leaders' smiles reflect these cultural differences in ideal affect. In Study 1, we compared the smiles of top-ranked American and Chinese government leaders, chief executive officers, and university presidents in their official photos. Consistent with findings that Americans value excitement and other high-arousal positive states more than Chinese, American top-ranked leaders (N = 98) showed more excited smiles than Chinese top-ranked leaders (N = 91) across occupations. In Study 2, we compared the smiles of winning versus losing political candidates and higher versus lower ranking chief executive officers and university presidents in the United States and Taiwan/China. American leaders (N = 223) showed more excited smiles than Taiwanese/Chinese leaders (N = 266), regardless of election outcome or ranking. In Study 3, we administered self-report measures of ideal affect in college student samples from 10 different nations (N = 1,267) and then 8 years later, coded the smiles that legislators from those nations showed in their official photos (N = 3,372). The more nations valued excitement and other high arousal positive states, the more their leaders showed excited smiles; similarly, the more nations valued calm and other low-arousal positive states, the more their leaders showed calm smiles. These results held after controlling for national differences in democratization, human development, and gross domestic product per capita. Together, these findings suggest that leaders' smiles reflect the affective states valued by their cultures. (c) 2016 APA, all rights reserved).

  13. Leaders’ Smiles Reflect Cultural Differences in Ideal Affect

    Science.gov (United States)

    Tsai, Jeanne L.; Ang, Jen Ying Zhen; Blevins, Elizabeth; Goernandt, Julia; Fung, Helene H.; Jiang, Da; Elliott, Julian; Kölzer, Anna; Uchida, Yukiko; Lee, Yi-Chen; Lin, Yicheng; Zhang, Xiulan; Govindama, Yolande; Haddouk, Lise

    2015-01-01

    Cultures differ in the emotions they teach their members to value (“ideal affect”). We conducted three studies to examine whether leaders’ smiles reflect these cultural differences in ideal affect. In Study 1, we compared the smiles of top ranked American and Chinese government leaders, chief-executive-officers (CEOs), and university presidents in their official photos. Consistent with findings that Americans value excitement and other high arousal positive states more than Chinese, American top ranked leaders (N = 98) showed more excited smiles than Chinese top ranked leaders (N = 91) across occupations. In Study 2, we compared the smiles of winning vs. losing political candidates and higher vs. lower ranking CEOs and university presidents in the US and Taiwan/China. American leaders (N = 223) showed more excited smiles than Taiwanese/Chinese leaders (N =266), regardless of election outcome or ranking. In Study 3, we administered self-report measures of ideal affect in college student samples from 10 different nations (N = 1,267) and then eight years later, coded the smiles that legislators from those nations showed in their official photos (N = 3,372). The more nations valued excitement and other high arousal positive states, the more their leaders showed excited smiles; similarly, the more nations valued calm and other low arousal positive states, the more their leaders showed calm smiles. These results held after controlling for national differences in GDP per capita, democratization, and human development. Together, these findings suggest that leaders’ smiles reflect the affective states valued by their cultures. PMID:26751631

  14. Oblique-incidence reflectivity difference application for morphology detection.

    Science.gov (United States)

    Zhan, Honglei; Zhao, Kun; Lü, Huibin; Jin, Kuijuan; Yang, Guozhen; Chen, Xiaohong

    2017-10-20

    Analogous with scanning electron microscopy, we use an oblique-incidence reflectivity difference (OIRD) approach for morphology detection. By scanning the active carbon clusters in a one-dimensional way and the reservoir rocks in a two-dimensional way, the morphology of the samples' surface can be revealed in OIRD signal images. High OIRD signals of active carbon samples refer to the centralized distribution areas of carbon, and the fluctuations are caused by the uneven distribution of carbon pellets. OIRD intensity is proportional to the thickness of materials. In terms of rocks, the trough areas with smaller values refer to the low-lying fields. The areas with relatively large OIRD intensities correspond to the protuberance areas of rocks. Consequently, OIRD is a sensitive yet rapid measure of surface detection in material and petrogeology science.

  15. Self-Reflection, Insight, and Individual Differences in Various Language Tasks

    Science.gov (United States)

    Xu, Xu

    2011-01-01

    This study explored the relationships of self-reflection and insight with individuals' performances on various language tasks. The Self-Reflection and Insight Scale (SRIS; Grant, Franklin, & Langford, 2002) assessed individual differences in three factors: engagement in reflection, need for reflection, and insight. A high need for reflection was…

  16. Observation and analysis of water inherent optical properties

    Science.gov (United States)

    Sun, Deyong; Li, Yunmei; Le, Chengfeng; Huang, Changchun

    2008-03-01

    Inherent optical property is an important part of water optical properties, and is the foundation of water color analytical model establishment. Through quantity filter technology (QFT) and backscattering meter BB9 (WETlabs Inc), absorption coefficients of CDOM, total suspended minerals and backscattering coefficients of total suspended minerals had been observed in Meiliang Bay of Taihu lake at summer and winter respectively. After analyzing the spectral characteristics of absorption and backscattering coefficients, the differences between two seasons had been illustrated adequately, and the reasons for the phenomena, which are related to the changes of water quality coefficient, had also been explained. So water environment states can be reflected by inherent optical properties. In addition, the relationship models between backscattering coefficients and suspended particle concentrations had been established, which can support coefficients for analytical models.

  17. Inherently safe light water reactors

    International Nuclear Information System (INIS)

    Ise, Takeharu

    1987-01-01

    Today's large nuclear power reactors of world-wise use have been designed based on the philosophy. It seems that recent less electricity demand rates, higher capital cost and the TMI accident let us acknowledge relative small and simplified nuclear plants with safer features, and that Chernobyl accident in 1983 underlines the needs of intrinsic and passive safety characteristics. In such background, several inherently safe reactor concepts have been presented abroad and domestically. First describing 'Can inherently safe reactors be designed,' then I introduce representative reactor concepts of inherently safe LWRs advocated abroad so far. All of these innovative reactors employ intrinsic and passive features in their design, as follows: (1) PIUS, an acronym for Process Inherent Ultimate Safety, or an integral PWR with passive heat sink and passive shutdown mechanism, advocated by ASEA-ATOM of Sweden. (2) MAP(Minimum Attention Plant), or a self-pressurized, natural circulation integral PWR, promoted by CE Inc. of the U.S. (3) TPS(TRIGA Power System), or a compact PWR with passive heat sink and inherent fuel characteristics of large prompt temperature coefficient, prompted by GA Technologies Inc. of the U.S. (4) PIUS-BWR, or an inherently safe BWR employing passively actuated fluid valves, in competition with PIUS, prompted by ORNL of the U.S. Then, I will describe the domestic trends in Japan and the innovative inherently safe LWRs presented domestically so far. (author)

  18. Reflections on the different sides of idleness in contemporary times

    Directory of Open Access Journals (Sweden)

    Patrícia Zaczuk Bassinello

    2015-04-01

    Full Text Available Over the last century, idleness experienced a modernization and democratization process especially with the crisis of a society focused on work – the post-Industrial Revolution - and the emergence of new ideas that put the free time, the leisure and recreation in the role of structural elements of the new social context and like tools for the new ways of life. In this work, we we seek to focus on the significant aspects of reality and function of leisure in our time, clarifying their relationship with the processes of personal, social and economic innovation by establishing a balance of our acts in thinking the leisure and work and leisure and life from different angles of approach. In order to analyze this phenomenon, we were based on scientific sources which are representative in the context, and then we elaborated a general overview of the subject from the contributions of the bakhtinian perspectives. We observed that the increase in leisure options in the last decades of the twentieth century, along with the growth of the studies of the idleness phenomenon and its possibilities, allowed an evolution of its concepts, from activities or practices associated to the consumption and to digital entertainment, to its understanding as an experience whose key of the discussion is the subject living these experiences. We believe that this reflection about idleness may open possibilities of a better comprehension of its insertion in the social and human sciences field and, especially, in its contribution to a new attitude of the relational production, centered on the subject, which stimulates a society that creates and innovates goods and services and who deepens the studies of leisure from the dynamic experiential horizon to the right to the otherness and to its time – the own one and the others’ – such as "the right to unfunctionality", from listening to the other word.

  19. Differences between winter oilseed rape (Brassica napus L.) cultivars in nitrogen starvation-induced leaf senescence are governed by leaf-inherent rather than root-derived signals

    Czech Academy of Sciences Publication Activity Database

    Koeslin-Findeklee, F.; Becker, M. A.; van der Graaff, E.; Roitsch, Thomas; Horst, W. J.

    2015-01-01

    Roč. 66, č. 13 (2015), s. 3669-3681 ISSN 0022-0957 Institutional support: RVO:67179843 Keywords : Brassica napus * cytokinins * genotypic differences * leaf senescence * nitrogen efficiency * nitrogen starvation * reciprocal grafting * stay-green Subject RIV: EH - Ecology, Behaviour Impact factor: 5.677, year: 2015

  20. Inherent X-Linked Genetic Variability and Cellular Mosaicism Unique to Females Contribute to Sex-Related Differences in the Innate Immune Response

    Directory of Open Access Journals (Sweden)

    Zoltan Spolarics

    2017-11-01

    Full Text Available Females have a longer lifespan and better general health than males. Considerable number of studies also demonstrated that, after trauma and sepsis, females present better outcomes as compared to males indicating sex-related differences in the innate immune response. The current notion is that differences in the immuno-modulatory effects of sex hormones are the underlying causative mechanism. However, the field remains controversial and the exclusive role of sex hormones has been challenged. Here, we propose that polymorphic X-linked immune competent genes, which are abundant in the population are important players in sex-based immuno-modulation and play a key role in causing sex-related outcome differences following trauma or sepsis. We describe the differences in X chromosome (ChrX regulation between males and females and its consequences in the context of common X-linked polymorphisms at the individual as well as population level. We also discuss the potential pathophysiological and immune-modulatory aspects of ChrX cellular mosaicism, which is unique to females and how this may contribute to sex-biased immune-modulation. The potential confounding effects of ChrX skewing of cell progenitors at the bone marrow is also presented together with aspects of acute trauma-induced de novo ChrX skewing at the periphery. In support of the hypothesis, novel observations indicating ChrX skewing in a female trauma cohort as well as case studies depicting the temporal relationship between trauma-induced cellular skewing and the clinical course are also described. Finally, we list and discuss a selected set of polymorphic X-linked genes, which are frequent in the population and have key regulatory or metabolic functions in the innate immune response and, therefore, are primary candidates for mediating sex-biased immune responses. We conclude that sex-related differences in a variety of disease processes including the innate inflammatory response to injury

  1. Informing patients of risks inherent in treatment.

    Science.gov (United States)

    Griffith, Richard; Tengnah, Cassam

    2009-11-01

    Consent to treatment lies at the heart of autonomous decision making by patients who are entitled to make a free choice about whether to accept or refuse treatment. To help patients arrive at their decision district nurses must ensure that they give sufficient information about the nature and risks inherent in the treatment to allow an informed choice to be made. This article considers how much information regarding risks needs to be disclosed. It discusses how the law requires a different level of disclosure for patients who ask no questions about risks, those who make general enquiries about risks and those who ask specific questions about the risks inherent in treatment.

  2. Reflections

    Directory of Open Access Journals (Sweden)

    Joanne Embree

    2001-01-01

    Full Text Available Ideally, editorials are written one to two months before publication in the Journal. It was my turn to write this one. I had planned to write the first draft the evening after my clinic on Tuesday, September 11. It didn't get done that night or during the next week. Somehow, the topic that I had originally chosen just didn't seem that important anymore as I, along my friends and colleagues, reflected on the changes that the events of that day were likely to have on our lives.

  3. Prospects for inherently safe reactors

    International Nuclear Information System (INIS)

    Barkenbus, J.N.

    1988-01-01

    Public fears over nuclear safety have led some within the nuclear community to investigate the possibility of producing inherently safe nuclear reactors; that is, reactors that are transparently incapable of producing a core melt. While several promising designs of such reactors have been produced, support for large-scale research and development efforts has not been forthcoming. The prospects for commercialization of inherently safe reactors, therefore, are problematic; possible events such as further nuclear reactor accidents and superpower summits, could alter the present situation significantly. (author)

  4. Fusion blanket inherent safety assessment

    International Nuclear Information System (INIS)

    Sze, D.K.; Jung, J.; Cheng, E.T.

    1986-01-01

    Fusion has significant potential safety advantages. There is a strong incentive for designing fusion plants to ensure that inherent safety will be achieved. Accordingly, both the Tokamak Power Systems Studies and MINIMARS have identified inherent safety as a design goal. A necessary condition is for the blanket to maintain its configuration and integrity under all credible accident conditions. A main problem is caused by afterheat removal in an accident condition. In this regard, it is highly desirable to achieve the required level of protection of the plant capital investment and limitation of radioactivity release by systems that rely only on inherent properties of matter (e.g., thermal conductivity, specific heat, etc.) and without the use of active safety equipment. This paper assesses the conditions under which inherent safety is feasible. Three types of accident conditions are evaluated for two blankets. The blankets evaluated are a self cooled vanadium/lithium blanket and a self-cooled vanadium/Flibe blanket. The accident conditions evaluated are: (1) loss-of-flow accident; (2) loss-of-coolant accident (LOCA); and (3) partial loss-of-coolant accident

  5. The representation of inherent properties.

    Science.gov (United States)

    Prasada, Sandeep

    2014-10-01

    Research on the representation of generic knowledge suggests that inherent properties can have either a principled or a causal connection to a kind. The type of connection determines whether the outcome of the storytelling process will include intuitions of inevitability and a normative dimension and whether it will ground causal explanations.

  6. Functional connectivity patterns reflect individual differences in conflict adaptation.

    Science.gov (United States)

    Wang, Xiangpeng; Wang, Ting; Chen, Zhencai; Hitchman, Glenn; Liu, Yijun; Chen, Antao

    2015-04-01

    Individuals differ in the ability to utilize previous conflict information to optimize current conflict resolution, which is termed the conflict adaptation effect. Previous studies have linked individual differences in conflict adaptation to distinct brain regions. However, the network-based neural mechanisms subserving the individual differences of the conflict adaptation effect have not been studied. The present study employed a psychophysiological interaction (PPI) analysis with a color-naming Stroop task to examine this issue. The main results were as follows: (1) the anterior cingulate cortex (ACC)-seeded PPI revealed the involvement of the salience network (SN) in conflict adaptation, while the posterior parietal cortex (PPC)-seeded PPI revealed the engagement of the central executive network (CEN). (2) Participants with high conflict adaptation effect showed higher intra-CEN connectivity and lower intra-SN connectivity; while those with low conflict adaptation effect showed higher intra-SN connectivity and lower intra-CEN connectivity. (3) The PPC-centered intra-CEN connectivity positively predicted the conflict adaptation effect; while the ACC-centered intra-SN connectivity had a negative correlation with this effect. In conclusion, our data demonstrated that conflict adaptation is likely supported by the CEN and the SN, providing a new perspective on studying individual differences in conflict adaptation on the basis of large-scale networks. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Twitter Language Use Reflects Psychological Differences between Democrats and Republicans.

    Science.gov (United States)

    Sylwester, Karolina; Purver, Matthew

    2015-01-01

    Previous research has shown that political leanings correlate with various psychological factors. While surveys and experiments provide a rich source of information for political psychology, data from social networks can offer more naturalistic and robust material for analysis. This research investigates psychological differences between individuals of different political orientations on a social networking platform, Twitter. Based on previous findings, we hypothesized that the language used by liberals emphasizes their perception of uniqueness, contains more swear words, more anxiety-related words and more feeling-related words than conservatives' language. Conversely, we predicted that the language of conservatives emphasizes group membership and contains more references to achievement and religion than liberals' language. We analysed Twitter timelines of 5,373 followers of three Twitter accounts of the American Democratic and 5,386 followers of three accounts of the Republican parties' Congressional Organizations. The results support most of the predictions and previous findings, confirming that Twitter behaviour offers valid insights to offline behaviour.

  8. Different bacteriocin activities of Streptococcus mutans reflect distinct phylogenetic lineages

    DEFF Research Database (Denmark)

    Balakrishnan, M; Simmonds, RS; Kilian, Mogens

    2002-01-01

    Bacteriocins produced by mutans streptococci are known as mutacins. In this study 16 broadly active mutacin-producing Streptococcus mutans strains from New Zealand, North America and Europe were classified into four groups (A-D) on the basis of differences in their activity in deferred antagonism...... described by Caufield and co-workers. One of the New Zealand isolates of group A (S. mutans strain N) appeared to produce inhibitory activity similar to that of the group I prototype strain UA140. Four other New Zealand isolates of group B (S. mutans strains M19, M34, B34 and D14) had mutacin II......-like activity. The group B mutacin producers differed from the group A mutacin producers in their additional activity against Staph. aureus 46. Seven S. mutans strains (M46, B46, B57, M12, M28, B28 and 13M) were distinguished from the group A and group B mutacin producers in that they inhibited E. faecium TE1...

  9. Twitter Language Use Reflects Psychological Differences between Democrats and Republicans.

    Directory of Open Access Journals (Sweden)

    Karolina Sylwester

    Full Text Available Previous research has shown that political leanings correlate with various psychological factors. While surveys and experiments provide a rich source of information for political psychology, data from social networks can offer more naturalistic and robust material for analysis. This research investigates psychological differences between individuals of different political orientations on a social networking platform, Twitter. Based on previous findings, we hypothesized that the language used by liberals emphasizes their perception of uniqueness, contains more swear words, more anxiety-related words and more feeling-related words than conservatives' language. Conversely, we predicted that the language of conservatives emphasizes group membership and contains more references to achievement and religion than liberals' language. We analysed Twitter timelines of 5,373 followers of three Twitter accounts of the American Democratic and 5,386 followers of three accounts of the Republican parties' Congressional Organizations. The results support most of the predictions and previous findings, confirming that Twitter behaviour offers valid insights to offline behaviour.

  10. Iser: an international inherently safe reactor concept

    International Nuclear Information System (INIS)

    Wakabayashi, Hiroaki

    1988-01-01

    Iser is a modular standardised 200-300 MWe power reactor based on the PIUS principle. It differs from PIUS in being simpler, and making full use of existing steel-vessel-based LWR technology. Iser is an inherently safe reactor concept under development in Japan. It is a generic concept, not a patented commodity, and it is expected that an international association to develop the concept will be formed. (U.K.)

  11. MHTGR inherent heat transfer capability

    International Nuclear Information System (INIS)

    Berkoe, J.M.

    1992-01-01

    This paper reports on the Commercial Modular High Temperature Gas-Cooled Reactor (MHTGR) which achieves improved reactor safety performance and reliability by utilizing a completely passive natural convection cooling system called the RCCS to remove decay heat in the event that all active cooling systems fail to operate. For the highly improbable condition that the RCCS were to become non-functional following a reactor depressurization event, the plant would be forced to rely upon its inherent thermo-physical characteristics to reject decay heat to the surrounding earth and ambient environment. A computational heat transfer model was created to simulate such a scenario. Plant component temperature histories were computed over a period of 20 days into the event. The results clearly demonstrate the capability of the MHTGR to maintain core integrity and provide substantial lead time for taking corrective measures

  12. The impact of different reference panels on spectral reflectance coefficients of some biological water pollutants

    Science.gov (United States)

    Jenerowicz, Agnieszka; Walczykowski, Piotr

    2015-10-01

    Monitoring of water environment and ecosystem, detecting water contaminants and understanding water quality parameters are most important tasks in water management and protection of whole aquatic environment. Detection of biological contaminants play a very important role in preserving human health and water management. To obtain accurate and precise results of determination of the level of biological contamination and to distinguish its type it is necessary to determine precisely spectral reflectance coefficients of several water biological pollutants with inter alia spectroradiometer. This paper presents a methodology and preliminary results of acquisition of spectral reflectance coefficients with different reference panels (e.g. with 5%, 20%, 50%, 80% and 96% of reflectivity) of several biological pollutants. The authors' main task was to measure spectral reflectance coefficients of different biological water pollutants with several reference panels and to select optimal reference standard, which would allow for distinguish different types of several biological contaminants. Moreover it was necessary to indicate the spectral range in which it is possible to discriminate investigated samples of biological contaminants. By conducting many series of measurements of several samples of different types of biological pollutants, authors had concluded how the reflectivity of reference panel influences the accuracy of acquisition of spectral reflectance coefficients. This research was crucial in order to be able to distinguish several types of biological pollutants and to determine the useful spectral range for detection of different kinds of biological contaminants with multispectral and hyperspectral imagery.

  13. Is human fracture hematoma inherently angiogenic?

    LENUS (Irish Health Repository)

    Street, J

    2012-02-03

    This study attempts to explain the cellular events characterizing the changes seen in the medullary callus adjacent to the interfragmentary hematoma during the early stages of fracture healing. It also shows that human fracture hematoma contains the angiogenic cytokine vascular endothelial growth factor and has the inherent capability to induce angiogenesis and thus promote revascularization during bone repair. Patients undergoing emergency surgery for isolated bony injury were studied. Raised circulating levels of vascular endothelial growth factor were seen in all injured patients, whereas the fracture hematoma contained significantly higher levels of vascular endothelial growth factor than did plasma from these injured patients. However, incubation of endothelial cells in fracture hematoma supernatant significantly inhibited the in vitro angiogenic parameters of endothelial cell proliferation and microtubule formation. These phenomena are dependent on a local biochemical milieu that does not support cytokinesis. The hematoma potassium concentration is cytotoxic to endothelial cells and osteoblasts. Subcutaneous transplantation of the fracture hematoma into a murine wound model resulted in new blood vessel formation after hematoma resorption. This angiogenic effect is mediated by the significant concentrations of vascular endothelial growth factor found in the hematoma. This study identifies an angiogenic cytokine involved in human fracture healing and shows that fracture hematoma is inherently angiogenic. The differences between the in vitro and in vivo findings may explain the phenomenon of interfragmentary hematoma organization and resorption that precedes fracture revascularization.

  14. Cultural differences in emotion regulation during self-reflection on negative personal experiences.

    Science.gov (United States)

    Tsai, William; Lau, Anna S

    2013-01-01

    Reflecting on negative personal experiences has implications for mood that may vary as a function of specific domains (e.g., achievement vs. interpersonal) and cultural orientation (e.g., interdependence vs. independence). This study investigated cultural differences in the social-cognitive and affective processes undertaken as Easterners and Westerners reflected on negative interpersonal and performance experiences. One hundred Asian Americans and 92 European-American college students were randomly assigned to one of three conditions: interpersonal rejection, achievement failure, or a control condition. Results revealed that Asian Americans experienced greater distress than European Americans after self-reflecting over a failed interpersonal experience, suggesting cultural sensitivity in the relational domain. Consistent with theoretical predictions, analysis of the social cognitive and affective processes that participants engaged in during self-reflection provided some evidence that self-enhancement may buffer distress for European Americans, while emotion suppression may be adaptive for Asian Americans.

  15. Sensors and actuators inherent in biological species

    Science.gov (United States)

    Taya, Minoru; Stahlberg, Rainer; Li, Fanghong; Zhao, Ying Joyce

    2007-04-01

    This paper addresses examples of sensing and active mechanisms inherent in some biological species where both plants and animals cases are discussed: mechanosensors and actuators in Venus Fly Trap and cucumber tendrils, chemosensors in insects, two cases of interactions between different kingdoms, (i) cotton plant smart defense system and (ii) bird-of-paradise flower and hamming bird interaction. All these cases lead us to recognize how energy-efficient and flexible the biological sensors and actuators are. This review reveals the importance of integration of sensing and actuation functions into an autonomous system if we make biomimetic design of a set of new autonomous systems which can sense and actuate under a number of different stimuli and threats.

  16. Quick and Easy Measurements of the Inherent Optical Property of Water by Laser

    International Nuclear Information System (INIS)

    Izadi, Dina; Hajiesmaeilbaigi, Fereshteh

    2009-01-01

    To generate realistic images of natural waters, one must consider in some detail the interaction of light with the water body. The reflectance and attenuation coefficient of the second harmonic of Nd:YAG laser light through distilled water and a sample of water from the Oman Sea were measured in a solid-state laser laboratory to estimate inherent optical properties of natural waters. These measurements determined the bottom conditions and the impurities of the water. The water's reflectivity varied depending on the angle of incidence, height of the laser from water surface, wavelength of laser light, radiant intensities, and depth of water. In these experiments laser light propagated through the water nonlinearly, and different reflectance showed different bottom slopes. The differences among various water samples were obtained taking into account the exponential equation in attenuation coefficient versus depth graphs.

  17. The inherent politics of quality in public park management

    DEFF Research Database (Denmark)

    Lindholst, Andrej Christian; Konijnendijk, Cecil Cornelis; Fors, Hanna

    2012-01-01

    In this paper, we highlight and illustrate the inherent politics embedded in “quality” as a concept for managing public parks. Reflecting more generic quality concepts, contemporary quality models in park management include concepts for both operational, strategic and stakeholder management as well...... managing the park organisation itself. However, quality concepts and their application through various management models include as well as exclude the access, values and worldviews of particular interests. In this way, any particular quality concept and model embeds its own politics by inherent...... allocations of ‘who gets what, when and how’. We illustrate the inherent politics by providing a case study of a widely adopted quality model for operational management that has been adopted and implemented in Denmark as part of new public management reforms. In perspective, other quality concepts and models...

  18. Gender differences in category-specificity do not reflect innate dispositions

    DEFF Research Database (Denmark)

    Gerlach, Christian; Gainotti, Guido

    2016-01-01

    It is well established that certain categories of objects are processed more efficiently than others in specific tasks; a phenomenon known as category-specificity in perceptual and conceptual processing. In the last two decades there have also been several reports of gender differences in categor...... of this discrepancy is that previous reports of gender differences may have reflected differences in familiarity originating from socially-based gender roles....

  19. Geometries inherent to N=1 supergravities

    International Nuclear Information System (INIS)

    Galperin, A.S.; Ogievetsky, V.I.; Sokatchev, E.S.

    1981-01-01

    The first part of the talk is devoted to a consideration of linearized N=1 supergravities. The second main part deals with complex geometries inherent to different N=1 supergravities. A special attention is paid to a new version with local symmetry. It is connected to the special nonminimal case (n=0) having a remarkable property of supervolume preservation in Csup(4.4) superspace. Therefore the superdeterminant of change of variables from left to right-handed Rsup(4.4) parametrization is a dimensionless scalar. This geometric invariant has to be constrained to obtain an action. Solving such a constraint on vector and spinor prepotentials in Wess-Zumino gauge one obtains the new supergravity with 12+12 fields and local symmetry. A possible relaxation of this constraint is briefly considered (16+16 fields version) [ru

  20. Insular Activity during Passive Viewing of Aversive Stimuli Reflects Individual Differences in State Negative Affect

    Science.gov (United States)

    Meriau, Katja; Wartenburger, Isabell; Kazzer, Philipp; Prehn, Kristin; Villringer, Arno; van der Meer, Elke; Heekeren, Hauke R.

    2009-01-01

    People differ with regard to how they perceive, experience, and express negative affect. While trait negative affect reflects a stable, sustained personality trait, state negative affect represents a stimulus limited and temporally acute emotion. So far, little is known about the neural systems mediating the relationship between negative affect…

  1. Individual Differences in EEG Spectral Power Reflect Genetic Variance in Gray and White Matter Volumes

    NARCIS (Netherlands)

    Smit, D.J.A.; Boomsma, D.I.; Schnack, H.G.; Hulshoff Pol, H.E.; de Geus, E.J.C.

    2012-01-01

    The human electroencephalogram (EEG) consists of oscillations that reflect the summation of postsynaptic potentials at the dendritic tree of cortical neurons. The strength of the oscillations (EEG power) is a highly genetic trait that has been related to individual differences in many phenotypes,

  2. Can the inherence heuristic explain vitalistic reasoning?

    Science.gov (United States)

    Bastian, Brock

    2014-10-01

    Inherence is an important component of psychological essentialism. By drawing on vitalism as a way in which to explain this link, however, the authors appear to conflate causal explanations based on fixed features with those based on general causal forces. The disjuncture between these two types of explanatory principles highlights potential new avenues for the inherence heuristic.

  3. Inherently safe characteristics of nuclear reactors

    International Nuclear Information System (INIS)

    1989-01-01

    This report is based on a detailed study which was carried out by Colenco (a company of the Motor-Columbus Group) on behalf of the Commission of the European Communities (CEC). It presents a summary of this study and concentrates more on the generic issues involved in the subject of inherent safety in nuclear power plants. It is assumed that the reader is reasonably familiar with the design outline of the systems included in the report. The report examines the role of inherent design features in achieving the safety of nuclear power plants as an alternative to the practice, which is largely followed in current reactors, of achieving safety by the addition of engineered safety features. The report examines current reactor systems to identify the extent to which their characteristics are either already inherently safe or, on the other hand, have inherent characteristics that require protective action to be taken. It then considers the advantages of introducing design changes to improve their inherent safety characteristics. Next, it looks at some new reactor types for which claims of inherent safety are made to see to what extent these claims are justified. The general question is then considered whether adoption of the inherently safe reactors would give advantages (by reducing risk in real terms or by improving the public acceptability of nuclear power) which are sufficient to offset the expected high costs and the technical risks associated with any new technology

  4. Inherent safety, ethics and human error.

    Science.gov (United States)

    Papadaki, Maria

    2008-02-11

    stated. The reason this article is presented here is that I believe that often, complex accidents, similarly to insignificant ones, often demonstrate an attitude which can be characterized as "inherently unsafe". I take the view that the enormous human potential and the human ability to minimize accidents needs to become a focal point towards inherent safety. Restricting ourselves to human limitations and how we could "treat" or prevent humans from not making accidents needs to be re-addressed. The purpose of this presentation is to highlight observations and provoke a discussion on how we could possibly improve the understanding of safety related issues. I do not intent to reject or criticize existing methodologies. (The entire presentation is strongly influenced by Trevor Kletz's work although our views are often different.).

  5. Personality-dependent differences in problem-solving performance in a social context reflect foraging strategies.

    Science.gov (United States)

    Zandberg, Lies; Quinn, John L; Naguib, Marc; van Oers, Kees

    2017-01-01

    Individuals develop innovative behaviours to solve foraging challenges in the face of changing environmental conditions. Little is known about how individuals differ in their tendency to solve problems and in their subsequent use of this solving behaviour in social contexts. Here we investigated whether individual variation in problem-solving performance could be explained by differences in the likelihood of solving the task, or if they reflect differences in foraging strategy. We tested this by studying the use of a novel foraging skill in groups of great tits (Parus major), consisting of three naive individuals with different personality, and one knowledgeable tutor. We presented them with multiple, identical foraging devices over eight trials. Though birds of different personality type did not differ in solving latency; fast and slow explorers showed a steeper increase over time in their solving rate, compared to intermediate explorers. Despite equal solving potential, personality influenced the subsequent use of the skill, as well as the pay-off received from solving. Thus, variation in the tendency to solve the task reflected differences in foraging strategy among individuals linked to their personality. These results emphasize the importance of considering the social context to fully understand the implications of learning novel skills. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Licensing issues for inherently safe fast reactors

    International Nuclear Information System (INIS)

    Kastenberg, W.E.; Lee, S.; Okrent, D.

    1986-01-01

    There has been considerable interest recently in a new generation of liquid metal reactor (LMR) concepts in the US. Some significant changes in regulatory philosophy will be required if the anticipated cost advantages of inherently safe designs are to be achieved. The defense in depth philosophy will need to be significantly re-evaluated in the context of inherently safe reactors. It is the purpose of this paper to begin such a re-evaluation of this regulatory philosophy

  7. Arterial stiffness and wave reflection: sex differences and relationship with left ventricular diastolic function.

    Science.gov (United States)

    Russo, Cesare; Jin, Zhezhen; Palmieri, Vittorio; Homma, Shunichi; Rundek, Tatjana; Elkind, Mitchell S V; Sacco, Ralph L; Di Tullio, Marco R

    2012-08-01

    Increased arterial stiffness and wave reflection have been reported in heart failure with normal ejection fraction (HFNEF) and in asymptomatic left ventricular (LV) diastolic dysfunction, a precursor of HFNEF. It is unclear whether women, who have higher frequency of HFNEF, are more vulnerable than men to the deleterious effects of arterial stiffness on LV diastolic function. We investigated, in a large community-based cohort, whether sex differences exist in the relationship among arterial stiffness, wave reflection, and LV diastolic function. Arterial stiffness and wave reflection were assessed in 983 participants from the Cardiovascular Abnormalities and Brain Lesions study using applanation tonometry. The central pulse pressure/stroke volume index, total arterial compliance, pulse pressure amplification, and augmentation index were used as parameters of arterial stiffness and wave reflection. LV diastolic function was evaluated by 2-dimensional echocardiography and tissue-Doppler imaging. Arterial stiffness and wave reflection were greater in women compared with men, independent of body size and heart rate (all Pfunction in both sexes. Further adjustment for cardiovascular risk factors attenuated these relationships; however, a higher central pulse pressure/stroke volume index predicted LV diastolic dysfunction in women (odds ratio, 1.54; 95% confidence intervals, 1.03 to 2.30) and men (odds ratio, 2.09; 95% confidence interval, 1.30 to 3.39), independent of other risk factors. In conclusion, in our community-based cohort study, higher arterial stiffness was associated with worse LV diastolic function in men and women. Women's higher arterial stiffness, independent of body size, may contribute to their greater susceptibility to develop HFNEF.

  8. Polarization contrast linear spectroscopies for cubic semiconductors under stress: macro- and micro-reflectance difference spectroscopies

    Energy Technology Data Exchange (ETDEWEB)

    Lastras-Martinez, L.F.; Balderas-Navarro, R.E.; Castro-Garcia, R.; Herrera-Jasso, R.; Lastras-Martinez, A. [Instituto de Investigacion en Comunicacion Optica, Universidad Autonoma de San Luis Potosi, Alvaro Obregon 64, 78000 San Luis Potosi, S.L.P. (Mexico); Chavira-Rodriguez, M. [Departamento de Fisico Matematicas, Universidad Autonoma de San Luis Potosi, Alvaro Obregon 64, 78000 San Luis Potosi, S.L.P. (Mexico)

    2011-01-15

    The technique to measure optical anisotropies (OA) in cubic semiconductors is termed either reflectance difference spectroscopy (RDS) or reflectance anisotropy spectroscopy (RAS). In this paper we report on the application of RDS/RAS to a number of cubic semiconductors. We discuss RD spectra of GaAs, Si, CdTe, GaP, InP and GaSb (001) surfaces, induced by an uniaxial stress applied along [110] crystal directions. We show that all RD spectra can be explained in terms of a phenomenological model based on a perturbative Hamiltonian. We further report on measurements of spatial-resolved RDS measurements of GaAs employing a newly developed micro-RD spectrometer with a spatial resolution of 5 {mu}m. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  9. Developing Students’ Reflections about the Function and Status of Mathematical Modeling in Different Scientific Practices

    DEFF Research Database (Denmark)

    Kjeldsen, Tinne Hoff; Blomhøj, Morten

    2013-01-01

    position held by the modeler(s) and the practitioners in the extra-mathematical domain. For students to experience the significance of different scientific practices and cultures for the function and status of mathematical modeling in other sciences, students need to be placed in didactical situations......Mathematical models and mathematical modeling play different roles in the different areas and problems in which they are used. The function and status of mathematical modeling and models in the different areas depend on the scientific practice as well as the underlying philosophical and theoretical...... where such differences are exposed and made into explicit objects of their reflections. It can be difficult to create such situations in the teaching of contemporary science in which modeling is part of the culture. In this paper we show how history can serve as a means for students to be engaged...

  10. Is it about "pink" or about "girls"? The inherence heuristic across social and nonsocial domains.

    Science.gov (United States)

    Kinzler, Katherine D; Sullivan, Kathleen R

    2014-10-01

    The inherence heuristic provides an intriguing and novel explanation for early thought in a variety of domains. Exploring similarities and differences in inherent reasoning across social and nonsocial domains can help us understand the role that inherent thinking plays in the development of human reasoning and the process by which more elaborate essentialist reasoning develops.

  11. Chlorophyll fluorescence, photochemical reflective index and normalized difference vegetative index during plant senescence.

    Science.gov (United States)

    Cordon, Gabriela; Lagorio, M Gabriela; Paruelo, José M

    2016-07-20

    The relationship between the Photochemical Reflectance Index (PRI), Normalized Difference Vegetation Index (NDVI) and chlorophyll fluorescence along senescence was investigated in this work. Reflectance and radiance measurements were performed at canopy level in grass species presenting different photosynthetic metabolism: Avena sativa (C3) and Setaria italica (C4), at different stages of the natural senescence process. Sun induced-chlorophyll fluorescence at 760nm (SIF 760 ) and the apparent fluorescence yield (SIF 760 /a, with a=irradiance at time of measurement) were extracted from the radiance spectra of canopies using the Fraunhofer Line Discrimination-method. The photosynthetic parameters derived from Kautsky kinetics and pigment content were also calculated at leaf level. Whilst stand level NDVI patterns were related to changes in the structure of canopies and not in pigment content, stand level PRI patterns suggested changes both in terms of canopy and of pigment content in leaves. Both SIF 760 /a and Φ PSII decreased progressively along senescence in both species. A strong increment in NPQ was evident in A. sativa while in S. italica NPQ values were lower. Our most important finding was that two chlorophyll fluorescence signals, Φ PSII and SIF 760 /a, correlated with the canopy PRI values in the two grasses assessed, even when tissues at different ontogenic stages were present. Even though significant changes occurred in the Total Chlr/Car ratio along senescence in both studied species, significant correlations between PRI and chlorophyll fluorescence signals might indicate the usefulness of this reflectance index as a proxy of photosynthetic RUE, at least under the conditions of this study. The relationships between stand level PRI and the fluorescence estimators (Φ PSII and SIF 760 /a) were positive in both cases. Therefore, an increase in PRI values as in the fluorescence parameters would indicate higher RUE. Copyright © 2016 Elsevier GmbH. All

  12. Comparison of Landsat-8 and Sentinel-2A reflectance and normalized difference vegetation index

    Science.gov (United States)

    Zhang, H.; Roy, D. P.; Yan, L.; Li, Z.; Huang, H.

    2017-12-01

    The moderate spatial resolution satellite data from the polar-orbiting Landsat-8 (launched 2013) and Sentinel-2A (launched 2015) sensors provide 10 m to 30 m multi-spectral global coverage with a better than 5-day revisit. Although a national laboratory traceable cross-calibration comparison of the Landsat-8 Operational Land Imager (OLI) and the Sentinel-2A MultiSpectral Instrument (MSI) was undertaken pre-launch, there are a number of other sensor differences, notably due to spectral, spatial and angular differences. To examine these in a comprehensive way, Landsat-8 and Sentinel-2A data for approximately 20° × 10° of southern Africa acquired in the summer (January to March) and winter (July to September) of 2016 were compared. Only Landsat-8 and Sentinel-2A observations acquired within one-day apart were considered. The sensor data were registered and then each orbit projected into 30 m fixed global Web Enabled Landsat Data (GWELD) tiles defined in the MODIS sinusoidal equal area projection. Only corresponding sensor observations of each 30 m tile pixel that were flagged as cloud and snow-free, unsaturated, and that had no significant change in their one day separation, were compared. Both the Landsat-8 and Sentinel-2A data were atmospherically corrected using the Landsat Surface Reflectance Code (LaSRC) and were also corrected to nadir BRDF adjusted reflectance (NBAR). Top of atmosphere and surface reflectance for the spectrally corresponding visible, near infrared and shortwave infrared OLI and MSI bands, and derived normalized difference vegetation index (NDVI), were compared and their differences quantified using regression analyses. The resulting statistical transformations may be used to improve the consistency between the Landsat-8 OLI and Sentinel-2A MSI data. The importance and sensitivity of the results to correct filtering, atmospheric correction and adjustment to NBAR is demonstrated.

  13. Implications of inherent safe nuclear power system

    International Nuclear Information System (INIS)

    Song, Yo-Taik

    1987-01-01

    The safety of present day nuclear power reactors and research reactors depends on a combination of design features of passive and active systems, and the alert judgement of their operators. A few inherently safe designs of nuclear reactors for power plants are currently under development. In these designs, the passive systems are emphasized, and the active systems are minimized. Also efforts are made to eliminate the potential for human failures that initiate the series of accidents. If a major system fails in these designs, the core is flooded automatically with coolants that flow by gravity, not by mechanical pumps or electromagnetic actuators. Depending on the choice of the coolants--water, liquid metal and helium gas--there are three principal types of inherently safe reactors. In this paper, these inherently safe reactor designs are reviewed and their implications are discussed. Further, future perspectives of their acceptance by nuclear industries are discussed. (author)

  14. Diversity in action: exchange of perspectives and reflections on taxonomies of individual differences.

    Science.gov (United States)

    Uher, Jana; Trofimova, Irina; Sulis, William; Netter, Petra; Pessoa, Luiz; Posner, Michael I; Rothbart, Mary K; Rusalov, Vladimir; Peterson, Isaac T; Schmidt, Louis A

    2018-04-19

    Throughout the last 2500 years, the classification of individual differences in healthy people and their extreme expressions in mental disorders has remained one of the most difficult challenges in science that affects our ability to explore individuals' functioning, underlying psychobiological processes and pathways of development. To facilitate analyses of the principles required for studying individual differences, this theme issue brought together prominent scholars from diverse backgrounds of which many bring unique combinations of cross-disciplinary experiences and perspectives that help establish connections and promote exchange across disciplines. This final paper presents brief commentaries of some of our authors and further scholars exchanging perspectives and reflecting on the contributions of this theme issue.This article is part of the theme issue 'Diverse perspectives on diversity: multi-disciplinary approaches to taxonomies of individual differences'. © 2018 The Author(s).

  15. Individual differences in competent consumer choice: the role of cognitive reflection and numeracy skills.

    Science.gov (United States)

    Graffeo, Michele; Polonio, Luca; Bonini, Nicolao

    2015-01-01

    In this paper, we investigate whether cognitive reflection and numeracy skills affect the quality of the consumers' decision-making process in a purchase decision context. In a first (field) experiment, an identical product was on sale in two shops with different initial prices and discounts. One of the two deals was better than the other and the consumers were asked to choose the best one and to describe which arithmetic operations they used to solve the problem; then they were asked to complete the numeracy scale (Lipkus et al., 2001). The choice procedures used by the consumers were classified as "complete decision approach" when all the arithmetic operations needed to solve the problem were computed, and as "partial decision approach" when only some operations were computed. A mediation model shows that higher numeracy is associated with use of the complete decision approach. In turn, this approach is positively associated with the quality of the purchase decision. Given that these findings highlight the importance of the decision processes, in a second (laboratory) experiment we used a supplementary method to study the type of information search used by the participants: eye-tracking. In this experiment the participants were presented with decision problems similar to those used in Experiment 1 and they completed the Lipkus numeracy scale and the Cognitive Reflection Test (CRT; Frederick, 2005). Participants with a high CRT score chose the best deal more frequently, and showed a more profound and detailed information search pattern compared to participants with a low CRT score. Overall, results indicate that higher levels of cognitive reflection and numeracy skills predict the use of a more thorough decision process (measured with two different techniques: retrospective verbal reports and eye movements). In both experiments the decision process is a crucial factor which greatly affects the quality of the purchase decision.

  16. Individual differences in competent consumer choice: the role of Cognitive Reflection and Numeracy skills

    Directory of Open Access Journals (Sweden)

    Michele eGraffeo

    2015-06-01

    Full Text Available In this paper, we investigate whether cognitive reflection and numeracy skills affect the quality of the consumers’ decision-making process in a purchase decision context. In a first (field experiment, an identical product was on sale in two shops with different initial prices and discounts. One of the two deals was better than the other and the consumers were asked to choose the best one and to describe which arithmetic operations they used to solve the problem; then they were asked to complete the numeracy scale (Lipkus et al., 2001. The choice procedures used by the consumers were classified as complete decision approach when all the arithmetic operations needed to solve the problem were computed, and as partial decision approach when only some operations were computed. A mediation model shows that higher numeracy is associated with use of the complete decision approach. In turn, this approach is positively associated with the quality of the purchase decision. Given that these findings highlight the importance of the decision processes, in a second (laboratory experiment we used a supplementary method to study the type of information search used by the participants: eye-tracking. In this experiment the participants were presented with decision problems similar to those used in experiment 1 and they completed the Lipkus numeracy scale and the Cognitive Reflection Test (CRT, (Frederick, 2005. Participants with a high CRT score chose the best deal more frequently, and showed a more profound and detailed information search pattern compared to participants with a low CRT score. Overall, results indicate that higher levels of cognitive reflection and numeracy skills predict the use of a more thorough decision process (measured with two different techniques: retrospective verbal reports and eye movements. In both experiments the decision process is a crucial factor which greatly affects the quality of the purchase decision.

  17. The contrasting nature of woody plant species in different neotropical forest biomes reflects differences in ecological stability.

    Science.gov (United States)

    Pennington, R Toby; Lavin, Matt

    2016-04-01

    A fundamental premise of this review is that distinctive phylogenetic and biogeographic patterns in clades endemic to different major biomes illuminate the evolutionary process. In seasonally dry tropical forests (SDTFs), phylogenies are geographically structured and multiple individuals representing single species coalesce. This pattern of monophyletic species, coupled with their old species stem ages, is indicative of maintenance of small effective population sizes over evolutionary timescales, which suggests that SDTF is difficult to immigrate into because of persistent resident lineages adapted to a stable, seasonally dry ecology. By contrast, lack of coalescence in conspecific accessions of abundant and often widespread species is more frequent in rain forests and is likely to reflect large effective population sizes maintained over huge areas by effective seed and pollen flow. Species nonmonophyly, young species stem ages and lack of geographical structure in rain forest phylogenies may reflect more widespread disturbance by drought and landscape evolution causing resident mortality that opens up greater opportunities for immigration and speciation. We recommend full species sampling and inclusion of multiple accessions representing individual species in phylogenies to highlight nonmonophyletic species, which we predict will be frequent in rain forest and savanna, and which represent excellent case studies of incipient speciation. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

  18. Individual differences in personality traits reflect structural variance in specific brain regions.

    Science.gov (United States)

    Gardini, Simona; Cloninger, C Robert; Venneri, Annalena

    2009-06-30

    Personality dimensions such as novelty seeking (NS), harm avoidance (HA), reward dependence (RD) and persistence (PER) are said to be heritable, stable across time and dependent on genetic and neurobiological factors. Recently a better understanding of the relationship between personality traits and brain structures/systems has become possible due to advances in neuroimaging techniques. This Magnetic Resonance Imaging (MRI) study investigated if individual differences in these personality traits reflected structural variance in specific brain regions. A large sample of eighty five young adult participants completed the Three-dimensional Personality Questionnaire (TPQ) and had their brain imaged with MRI. A voxel-based correlation analysis was carried out between individuals' personality trait scores and grey matter volume values extracted from 3D brain scans. NS correlated positively with grey matter volume in frontal and posterior cingulate regions. HA showed a negative correlation with grey matter volume in orbito-frontal, occipital and parietal structures. RD was negatively correlated with grey matter volume in the caudate nucleus and in the rectal frontal gyrus. PER showed a positive correlation with grey matter volume in the precuneus, paracentral lobule and parahippocampal gyrus. These results indicate that individual differences in the main personality dimensions of NS, HA, RD and PER, may reflect structural variance in specific brain areas.

  19. Individual Differences in Numeracy and Cognitive Reflection, with Implications for Biases and Fallacies in Probability Judgment.

    Science.gov (United States)

    Liberali, Jordana M; Reyna, Valerie F; Furlan, Sarah; Stein, Lilian M; Pardo, Seth T

    2012-10-01

    Despite evidence that individual differences in numeracy affect judgment and decision making, the precise mechanisms underlying how such differences produce biases and fallacies remain unclear. Numeracy scales have been developed without sufficient theoretical grounding, and their relation to other cognitive tasks that assess numerical reasoning, such as the Cognitive Reflection Test (CRT), has been debated. In studies conducted in Brazil and in the USA, we administered an objective Numeracy Scale (NS), Subjective Numeracy Scale (SNS), and the CRT to assess whether they measured similar constructs. The Rational-Experiential Inventory, inhibition (go/no-go task), and intelligence were also investigated. By examining factor solutions along with frequent errors for questions that loaded on each factor, we characterized different types of processing captured by different items on these scales. We also tested the predictive power of these factors to account for biases and fallacies in probability judgments. In the first study, 259 Brazilian undergraduates were tested on the conjunction and disjunction fallacies. In the second study, 190 American undergraduates responded to a ratio-bias task. Across the different samples, the results were remarkably similar. The results indicated that the CRT is not just another numeracy scale, that objective and subjective numeracy scales do not measure an identical construct, and that different aspects of numeracy predict different biases and fallacies. Dimensions of numeracy included computational skills such as multiplying, proportional reasoning, mindless or verbatim matching, metacognitive monitoring, and understanding the gist of relative magnitude, consistent with dual-process theories such as fuzzy-trace theory.

  20. Disease resistance is related to inherent swimming performance in Atlantic salmon.

    Science.gov (United States)

    Castro, Vicente; Grisdale-Helland, Barbara; Jørgensen, Sven M; Helgerud, Jan; Claireaux, Guy; Farrell, Anthony P; Krasnov, Aleksei; Helland, Ståle J; Takle, Harald

    2013-01-21

    Like humans, fish can be classified according to their athletic performance. Sustained exercise training of fish can improve growth and physical capacity, and recent results have documented improved disease resistance in exercised Atlantic salmon. In this study we investigated the effects of inherent swimming performance and exercise training on disease resistance in Atlantic salmon.Atlantic salmon were first classified as either poor or good according to their swimming performance in a screening test and then exercise trained for 10 weeks using one of two constant-velocity or two interval-velocity training regimes for comparison against control trained fish (low speed continuously). Disease resistance was assessed by a viral disease challenge test (infectious pancreatic necrosis) and gene expression analyses of the host response in selected organs. An inherently good swimming performance was associated with improved disease resistance, as good swimmers showed significantly better survival compared to poor swimmers in the viral challenge test. Differences in mortalities between poor and good swimmers were correlated with cardiac mRNA expression of virus responsive genes reflecting the infection status. Although not significant, fish trained at constant-velocity showed a trend towards higher survival than fish trained at either short or long intervals. Finally, only constant training at high intensity had a significant positive effect on fish growth compared to control trained fish. This is the first evidence suggesting that inherent swimming performance is associated with disease resistance in fish.

  1. Disease resistance is related to inherent swimming performance in Atlantic salmon

    Directory of Open Access Journals (Sweden)

    Castro Vicente

    2013-01-01

    Full Text Available Abstract Background Like humans, fish can be classified according to their athletic performance. Sustained exercise training of fish can improve growth and physical capacity, and recent results have documented improved disease resistance in exercised Atlantic salmon. In this study we investigated the effects of inherent swimming performance and exercise training on disease resistance in Atlantic salmon. Atlantic salmon were first classified as either poor or good according to their swimming performance in a screening test and then exercise trained for 10 weeks using one of two constant-velocity or two interval-velocity training regimes for comparison against control trained fish (low speed continuously. Disease resistance was assessed by a viral disease challenge test (infectious pancreatic necrosis and gene expression analyses of the host response in selected organs. Results An inherently good swimming performance was associated with improved disease resistance, as good swimmers showed significantly better survival compared to poor swimmers in the viral challenge test. Differences in mortalities between poor and good swimmers were correlated with cardiac mRNA expression of virus responsive genes reflecting the infection status. Although not significant, fish trained at constant-velocity showed a trend towards higher survival than fish trained at either short or long intervals. Finally, only constant training at high intensity had a significant positive effect on fish growth compared to control trained fish. Conclusions This is the first evidence suggesting that inherent swimming performance is associated with disease resistance in fish.

  2. Real-time reflectance-difference spectroscopy of GaAs molecular beam epitaxy homoepitaxial growth

    Energy Technology Data Exchange (ETDEWEB)

    Lastras-Martínez, A., E-mail: alm@cactus.iico.uaslp.mx, E-mail: alastras@gmail.com; Ortega-Gallegos, J.; Guevara-Macías, L. E.; Nuñez-Olvera, O.; Balderas-Navarro, R. E.; Lastras-Martínez, L. F. [Instituto de Investigación en Comunicación Optica, Universidad Autónoma de San Luis Potosí, Alvaro Obregón 64, San Luis Potosí, SLP 78000 (Mexico); Lastras-Montaño, L. A. [IBM T. J. Watson Research Center, Yorktown Heights, New York 10598 (United States); Lastras-Montaño, M. A. [Department of Electrical and Computer Engineering, University of California, Santa Barbara, Santa Barbara, California 93106 (United States)

    2014-03-01

    We report on real time-resolved Reflectance-difference (RD) spectroscopy of GaAs(001) grown by molecular beam epitaxy, with a time-resolution of 500 ms per spectrum within the 2.3–4.0 eV photon energy range. Through the analysis of transient RD spectra we demonstrated that RD line shapes are comprised of two components with different physical origins and determined their evolution during growth. Such components were ascribed to the subsurface strain induced by surface reconstruction and to surface stoichiometry. Results reported in this paper render RD spectroscopy as a powerful tool for the study of fundamental processes during the epitaxial growth of zincblende semiconductors.

  3. Real-time reflectance-difference spectroscopy of GaAs molecular beam epitaxy homoepitaxial growth

    Directory of Open Access Journals (Sweden)

    A. Lastras-Martínez

    2014-03-01

    Full Text Available We report on real time-resolved Reflectance-difference (RD spectroscopy of GaAs(001 grown by molecular beam epitaxy, with a time-resolution of 500 ms per spectrum within the 2.3–4.0 eV photon energy range. Through the analysis of transient RD spectra we demonstrated that RD line shapes are comprised of two components with different physical origins and determined their evolution during growth. Such components were ascribed to the subsurface strain induced by surface reconstruction and to surface stoichiometry. Results reported in this paper render RD spectroscopy as a powerful tool for the study of fundamental processes during the epitaxial growth of zincblende semiconductors.

  4. Detection of the specific binding on protein microarrays by oblique-incidence reflectivity difference method

    International Nuclear Information System (INIS)

    Lu, Heng; Wen, Juan; Wang, Xu; Yuan, Kun; Lu, Huibin; Zhou, Yueliang; Jin, Kuijuan; Yang, Guozhen; Li, Wei; Ruan, Kangcheng

    2010-01-01

    The specific binding between Cy5-labeled goat anti-mouse Immunoglobulin G (IgG) and mouse IgG with a concentration range from 625 to 10 4 µg ml −1 has been detected successfully by the oblique-incidence reflectivity difference (OI-RD) method in each procedure of microarray fabrication. The experimental data prove that the OI-RD method can be employed not only to distinguish the different concentrations in label-free fashion but also to detect the antibody–antigen capture. In addition, the differential treatment of the OI-RD signals can decrease the negative influences of glass slide as the microarray upholder. Therefore the OI-RD technique has promising applications for the label-free and high-throughput detection of protein microarrays

  5. Gender Differences in Performance Predictions: Evidence from the Cognitive Reflection Test.

    Science.gov (United States)

    Ring, Patrick; Neyse, Levent; David-Barett, Tamas; Schmidt, Ulrich

    2016-01-01

    This paper studies performance predictions in the 7-item Cognitive Reflection Test (CRT) and whether they differ by gender. After participants completed the CRT, they predicted their own (i), the other participants' (ii), men's (iii), and women's (iv) number of correct answers. In keeping with existing literature, men scored higher on the CRT than women and both men and women were too optimistic about their own performance. When we compare gender-specific predictions, we observe that men think they perform significantly better than other men and do so significantly more than women. The equality between women's predictions about their own performance and their female peers cannot be rejected. Our findings contribute to the growing literature on the underpinnings of behavior in economics and in psychology by uncovering gender differences in confidence about one's ability relative to same and opposite sex peers.

  6. Gender Differences in Performance Predictions: Evidence from the Cognitive Reflection Test

    Directory of Open Access Journals (Sweden)

    Patrick Ring

    2016-11-01

    Full Text Available This paper studies performance predictions in the 7-item Cognitive Reflection Test (CRT and whether they differ by gender. After participants completed the CRT, they predicted their own (i, the other participants’ (ii, men’s (iii, and women’s (iv number of correct answers. In keeping with existing literature, men scored higher on the CRT than women and both men and women were too optimistic about their own performance. When we compare gender-specific predictions, we observe that men think they perform significantly better than other men and do so significantly more than women. The equality between women’s predictions about their own performance and their female peers cannot be rejected. Our findings contribute to the growing literature on the underpinnings of behavior in economics and in psychology by uncovering gender differences in confidence about one’s ability relative to same and opposite sex peers.

  7. Students' Perception of Live Lectures' Inherent Disadvantages

    Science.gov (United States)

    Petrovic, Juraj; Pale, Predrag

    2015-01-01

    This paper aims to provide insight into various properties of live lectures from the perspective of sophomore engineering students. In an anonymous online survey conducted at the Faculty of Electrical Engineering and Computing, University of Zagreb, we investigated students' opinions regarding lecture attendance, inherent disadvantages of live…

  8. Categories of difference in science and policy: Reflections on academic practices, conceptualizations and knowledge production

    Directory of Open Access Journals (Sweden)

    Martin Bak Jørgensen

    2012-09-01

    Full Text Available Categories of difference have a crucial position in academic research as well as policy-making. They serve to distinguish and differentiate between groups in society. They can appear in the shape of crude dichotomies or in complex and sophisticated forms resting on constructivist and intersectionalist perspectives. Nevertheless, using categories of difference also creates something into existence and there may be implications through the particular application of specific categories. This article reflects on how categories of difference are constructed and employed in research, legislation and policy discourse. By looking at different approaches used by qualitative and quantitative researchers, as well as at how specific concepts enter policy-making and legislation, I want to address a number of questions about how we as researchers understand and work with categories of differences. The article will mainly consist of a theoretical discussion, but will use two main empirical examples of race and religion. The article aims to provide tentative answers about what the consequences of particular uses of categories and concepts could be.

  9. Junior high school students’ reflective thinking on fraction problem solving: In case of gender differences

    Science.gov (United States)

    Rasyid, M. A.; Budiarto, M. T.; Lukito, A.

    2018-01-01

    This study aims to describe reflective thinking of junior high school students on solving the fractions problem in terms of gender differences. This research is a qualitative approach involving one male student and one female student in seventh grade. The data were collected through the assignment of fractional problem solving and interview, then the data were triangulated and analyzed by three stages, namely data condensation, data display and conclusion. The results showed that the subjects of male and female were reacting, elaborating and contemplating at each stage of solving the fractions problem. But at the stage of devising the plan, the female subject was contemplating, relying more on their beliefs, did not consider their experience, in addition, the female subject didn’t use experience of the steps she planned to solve the problem of fractions.

  10. Individual Differences in Numeracy and Cognitive Reflection, with Implications for Biases and Fallacies in Probability Judgment

    Science.gov (United States)

    LIBERALI, JORDANA M.; REYNA, VALERIE F.; FURLAN, SARAH; STEIN, LILIAN M.; PARDO, SETH T.

    2013-01-01

    Despite evidence that individual differences in numeracy affect judgment and decision making, the precise mechanisms underlying how such differences produce biases and fallacies remain unclear. Numeracy scales have been developed without sufficient theoretical grounding, and their relation to other cognitive tasks that assess numerical reasoning, such as the Cognitive Reflection Test (CRT), has been debated. In studies conducted in Brazil and in the USA, we administered an objective Numeracy Scale (NS), Subjective Numeracy Scale (SNS), and the CRT to assess whether they measured similar constructs. The Rational–Experiential Inventory, inhibition (go/no-go task), and intelligence were also investigated. By examining factor solutions along with frequent errors for questions that loaded on each factor, we characterized different types of processing captured by different items on these scales. We also tested the predictive power of these factors to account for biases and fallacies in probability judgments. In the first study, 259 Brazilian undergraduates were tested on the conjunction and disjunction fallacies. In the second study, 190 American undergraduates responded to a ratio-bias task. Across the different samples, the results were remarkably similar. The results indicated that the CRT is not just another numeracy scale, that objective and subjective numeracy scales do not measure an identical construct, and that different aspects of numeracy predict different biases and fallacies. Dimensions of numeracy included computational skills such as multiplying, proportional reasoning, mindless or verbatim matching, metacognitive monitoring, and understanding the gist of relative magnitude, consistent with dual-process theories such as fuzzy-trace theory. PMID:23878413

  11. An inherently safe power reactor module

    International Nuclear Information System (INIS)

    Salerno, L.N.

    1985-01-01

    General Electric's long participation in liquid metal reactor technology has led to a Power Reactor Inherently Safe Module (PRISM) concept supported by DOE contract DE-AC06-85NE37937. The reactor module is sized to maximize inherent safety features. The small size allows factory fabrication, reducing field construction and field QA/QC labor, and allows safety to be demonstrated in full scale, to support a pre-licensed standard commercial product. The module is small enough to be placed underground, and can be combined with steam and electrical generating equipment to provide a complete electrical power producing plant in the range of 400-1200 MWe. Initial assessments are that the concept has the potential to be economically competitive with existing methods of power production used by the utility industry

  12. Inherently safe technologies-chemical and nuclear

    International Nuclear Information System (INIS)

    Weinberg, A.M.

    1984-01-01

    Probabilistic risk assessments show an inverse relationship between the likelihood and the consequences of nuclear and chemical plant accidents, but the Bhopal accident has change public complacency about the safety of chemical plants to such an extent that public confidence is now at the same low level as with nuclear plants. The nuclear industry's response was to strengthen its institutions and improve its technologies, but the public may not be convinced. One solution is to develop reactors which do not depend upon the active intervention of humans of electromechanical devices to deal with emergencies, but which have physical properties that limit the possible temperature and power of a reactor. The Process Inherent Ultimately Safe and the modular High-Temperature Gas-Cooled reactors are two possibilities. the chemical industry needs to develop its own inherently safe design precepts that incorporate smallness, safe processes, and hardening against sabotage. 5 references

  13. A general index of inherent risk

    OpenAIRE

    Schnytzer, Adi; Westreich, Sara

    2009-01-01

    We extend the pioneering work of Aumann and Serrano by presenting an index of inherent riskiness of a gamble having the desirable properties of their index, while being applicable to gambles with either positive or negative expectations. As such, our index provides a measure of riskiness which is of use for both risk lovers and risk aversive gamblers, and is defined for all discrete and a large class of continuous gambles. We analyze abstract properties of our index, and present in addition t...

  14. Bioenergetics during calvarial osteoblast differentiation reflect strain differences in bone mass.

    Science.gov (United States)

    Guntur, Anyonya R; Le, Phuong T; Farber, Charles R; Rosen, Clifford J

    2014-05-01

    Osteoblastogenesis is the process by which mesenchymal stem cells differentiate into osteoblasts that synthesize collagen and mineralize matrix. The pace and magnitude of this process are determined by multiple genetic and environmental factors. Two inbred strains of mice, C3H/HeJ and C57BL/6J, exhibit differences in peak bone mass and bone formation. Although all the heritable factors that differ between these strains have not been elucidated, a recent F1 hybrid expression panel (C3H × B6) revealed major genotypic differences in osteoblastic genes related to cellular respiration and oxidative phosphorylation. Thus, we hypothesized that the metabolic rate of energy utilization by osteoblasts differed by strain and would ultimately contribute to differences in bone formation. In order to study the bioenergetic profile of osteoblasts, we measured oxygen consumption rates (OCR) and extracellular acidification rates (ECAR) first in a preosteoblastic cell line MC3T3-E1C4 and subsequently in primary calvarial osteoblasts from C3H and B6 mice at days 7, 14, and 21 of differentiation. During osteoblast differentiation in media containing ascorbic acid and β-glycerophosphate, all 3 cell types increased their oxygen consumption and extracellular acidification rates compared with the same cells grown in regular media. These increases are sustained throughout differentiation. Importantly, C3H calvarial osteoblasts had greater oxygen consumption rates than B6 consistent with their in vivo phenotype of higher bone formation. Interestingly, osteoblasts utilized both oxidative phosphorylation and glycolysis during the differentiation process although mature osteoblasts were more dependent on glycolysis at the 21-day time point than oxidative phosphorylation. Thus, determinants of oxygen consumption reflect strain differences in bone mass and provide the first evidence that during collagen synthesis osteoblasts use both glycolysis and oxidative phosphorylation to synthesize and

  15. Implementation of inquiry-based science education in different countries: some reflections

    Science.gov (United States)

    Rundgren, Carl-Johan

    2017-03-01

    In this forum article, I reflect on issues related to the implementation of inquiry-based science education (IBSE) in different countries. Regarding education within the European Union (EU), the Bologna system has in later years provided extended coordination and comparability at an organizational level. However, the possibility of the EU to influence the member countries regarding the actual teaching and learning in the classrooms is more limited. In later years, several EU-projects focusing on IBSE have been funded in order to make science education in Europe better, and more motivating for students. Highlighting what Heinz and her colleagues call the policy of `soft governance' of the EU regarding how to improve science education in Europe, I discuss the focus on IBSE in the seventh framework projects, and how it is possible to maintain more long-lasting results in schools through well-designed teacher professional development programs. Another aspect highlighted by Heinz and her colleagues is how global pressures on convergence in education interact with educational structures and traditions in the individual countries. The rise of science and science education as a global culture, encompassing contributions from all around the world, is a phenomenon of great potential and value to humankind. However, it is important to bear in mind that if science and science education is going to become a truly global culture, local variation and differences regarding foci and applications of science in different cultures must be acknowledged.

  16. Relative differences in strength and power from slow to fast isokinetic velocities may reflect dynapenia.

    Science.gov (United States)

    Jenkins, Nathaniel D M; Housh, Terry J; Palmer, Ty B; Cochrane, Kristen C; Bergstrom, Haley C; Johnson, Glen O; Schmidt, Richard J; Cramer, Joel T

    2015-07-01

    We compared absolute and normalized values for peak torque (PT), mean power (MP), rate of velocity development, and electromyography (EMG) amplitude during maximal isometric and concentric isokinetic leg extension muscle actions, as well as the %decrease in PT and %increase in MP from 1.05 to 3.14 rad·s(-1) in younger versus older men. Measurements were performed twice for reliability. Isokinetic measurements were normalized to the isometric muscle actions. Absolute isometric PT, isokinetic PT and MP, and EMG amplitudes at 1.05 and 3.14 rad·s(-1) were greater in the younger men, although normalizing to isometric PT eliminated the age differences. The older men exhibited greater %decrease in PT (37.2% vs. 31.3%) and lower %increase in MP (87.6% vs. 126.4%) regardless of normalization. Normalization eliminated absolute differences in isokinetic strength and power, but the relative differences from slow to fast velocities may reflect dynapenia characterized by age-related decreases in fast-twitch fiber function. © 2014 Wiley Periodicals, Inc.

  17. Inherently safe high temperature gas-cooled reactor

    International Nuclear Information System (INIS)

    Yamada, Masao; Hayakawa, Hitoshi

    1987-01-01

    It is recognized in general that High Temperature Gas-cooled Reactors have remarkable characteristics in inherent safety and it is well known that credits of the time margin have been admitted for accident evaluation in the licensing of the currently operating prototype HTGRs (300 MWe class). Recently, more inherently safe HTGRs are being developed in various countries and drawing attention on their possibility for urban siting. The inherent safety characteristics of these HTRs differ each other depending on their design philosophy and on the features of the components/structures which constitute the plant. At first, the specific features/characteristics of the elemental components/structures of the HTRs are explained one by one and then the overall safety features/characteristics of these HTR plants are explained in connection with their design philosophy and combination of the elemental features. Taking the KWU/Interatom Modular Reactor System as an example, the particular design philosophy and safety characteristics of the inherently safe HTR are explained with a result of preliminary evaluation on the possibility of siting close to densely populated area. (author)

  18. Different size biomolecules anchoring on porous silicon surface: fluorescence and reflectivity pores infiltration comparative studies

    Energy Technology Data Exchange (ETDEWEB)

    Giovannozzi, Andrea M.; Rossi, Andrea M. [National Institute for Metrological Research, Thermodynamic Division, Strada delle Cacce 91, 10135 Torino (Italy); Renacco, Chiara; Farano, Alessandro [Ribes Ricecrhe Srl, Via Lavoratori Vittime del Col du Mont 24, 11100 Aosta (Italy); Derosas, Manuela [Biodiversity Srl, Via Corfu 71, 25124 Brescia (Italy); Enrico, Emanuele [National Institute for Metrological Research, Electromagnetism Division, Strada delle Cacce 91, 10135 Torino (Italy)

    2011-06-15

    The performance of porous silicon optical based biosensors strongly depends on material nanomorphology, on biomolecules distribution inside the pores and on the ability to link sensing species to the pore walls. In this paper we studied the immobilization of biomolecules with different size, such as antibody anti aflatoxin (anti Aflatox Ab, {proportional_to}150 KDa), malate dehydrogenase (MDH, {proportional_to}36KDa) and metallothionein (MT, {proportional_to}6KDa) at different concentrations on mesoporous silicon samples ({proportional_to}15 nm pores diameter). Fluorescence measurements using FITC- labeled biomolecules and refractive index analysis based on reflectivity spectra have been employed together to detect the amount of proteins bound to the surface and to evaluate their diffusion inside the pores. Here we suggest that these two techniques should be used together to have a better understanding of what happens at the porous silicon surface. In fact, when pores dimensions are not perfectly tuned to the protein size a higher fluorescence signal doesn't often correspond to a higher biomolecules distribution inside the pores. When a too much higher concentration of biomolecule is anchored on the surface, steric crowd effects and repulsive interactions probably take over and hinder pores infiltration, inducing a small or absent shift in the fringe pattern even if a higher fluorescence signal is registered. (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  19. Resting-state low-frequency fluctuations reflect individual differences in spoken language learning

    Science.gov (United States)

    Deng, Zhizhou; Chandrasekaran, Bharath; Wang, Suiping; Wong, Patrick C.M.

    2016-01-01

    A major challenge in language learning studies is to identify objective, pre-training predictors of success. Variation in the low-frequency fluctuations (LFFs) of spontaneous brain activity measured by resting-state functional magnetic resonance imaging (RS-fMRI) has been found to reflect individual differences in cognitive measures. In the present study, we aimed to investigate the extent to which initial spontaneous brain activity is related to individual differences in spoken language learning. We acquired RS-fMRI data and subsequently trained participants on a sound-to-word learning paradigm in which they learned to use foreign pitch patterns (from Mandarin Chinese) to signal word meaning. We performed amplitude of spontaneous low-frequency fluctuation (ALFF) analysis, graph theory-based analysis, and independent component analysis (ICA) to identify functional components of the LFFs in the resting-state. First, we examined the ALFF as a regional measure and showed that regional ALFFs in the left superior temporal gyrus were positively correlated with learning performance, whereas ALFFs in the default mode network (DMN) regions were negatively correlated with learning performance. Furthermore, the graph theory-based analysis indicated that the degree and local efficiency of the left superior temporal gyrus were positively correlated with learning performance. Finally, the default mode network and several task-positive resting-state networks (RSNs) were identified via the ICA. The “competition” (i.e., negative correlation) between the DMN and the dorsal attention network was negatively correlated with learning performance. Our results demonstrate that a) spontaneous brain activity can predict future language learning outcome without prior hypotheses (e.g., selection of regions of interest – ROIs) and b) both regional dynamics and network-level interactions in the resting brain can account for individual differences in future spoken language learning success

  20. Resting-state low-frequency fluctuations reflect individual differences in spoken language learning.

    Science.gov (United States)

    Deng, Zhizhou; Chandrasekaran, Bharath; Wang, Suiping; Wong, Patrick C M

    2016-03-01

    A major challenge in language learning studies is to identify objective, pre-training predictors of success. Variation in the low-frequency fluctuations (LFFs) of spontaneous brain activity measured by resting-state functional magnetic resonance imaging (RS-fMRI) has been found to reflect individual differences in cognitive measures. In the present study, we aimed to investigate the extent to which initial spontaneous brain activity is related to individual differences in spoken language learning. We acquired RS-fMRI data and subsequently trained participants on a sound-to-word learning paradigm in which they learned to use foreign pitch patterns (from Mandarin Chinese) to signal word meaning. We performed amplitude of spontaneous low-frequency fluctuation (ALFF) analysis, graph theory-based analysis, and independent component analysis (ICA) to identify functional components of the LFFs in the resting-state. First, we examined the ALFF as a regional measure and showed that regional ALFFs in the left superior temporal gyrus were positively correlated with learning performance, whereas ALFFs in the default mode network (DMN) regions were negatively correlated with learning performance. Furthermore, the graph theory-based analysis indicated that the degree and local efficiency of the left superior temporal gyrus were positively correlated with learning performance. Finally, the default mode network and several task-positive resting-state networks (RSNs) were identified via the ICA. The "competition" (i.e., negative correlation) between the DMN and the dorsal attention network was negatively correlated with learning performance. Our results demonstrate that a) spontaneous brain activity can predict future language learning outcome without prior hypotheses (e.g., selection of regions of interest--ROIs) and b) both regional dynamics and network-level interactions in the resting brain can account for individual differences in future spoken language learning success

  1. Integral fast reactor concept inherent safety features

    International Nuclear Information System (INIS)

    Marchaterre, J.F.; Sevy, R.H.; Cahalan, J.E.

    1987-01-01

    The Integral Fast Reactor (IFR) is an innovative liquid-metal-cooled reactor concept being developed at Argonne National Laboratory. The two major goals of the IFT development effort are improved economics and enhanced safety. The design features that together fulfill these goals are: 1) a liquid metal (sodium) coolant, 2) a pool-type reactor primary system configuration, 3) an advanced ternary alloy metallic fuel, and 4) an integral fuel cycle. This paper reviews the design features that contribute to the safety margins inherent to the IFR concept. Special emphasis is placed on the ability of the IFR design to accommodate anticipated transients without scram (ATWS)

  2. Integral Fast Reactor concept inherent safety features

    International Nuclear Information System (INIS)

    Marchaterre, J.F.; Sevy, R.H.; Cahalan, J.E.

    1986-01-01

    The Integral Fast Reactor (IFR) is an innovative liquid-metal-cooled reactor concept being developed at Argonne National Laboratory. The two major goals of the IFR development effort are improved economics and enhanced safety. The design features that together fulfill these goals are: (1) a liquid metal (sodium) coolant, (2) a pool-type reactor primary system configuration, (3) an advanced ternary alloy metallic fuel, and (4) an integral fuel cycle. This paper reviews the design features that contribute to the safety margins inherent to the IFR concept. Special emphasis is placed on the ability of the IFR design to accommodate anticipated transients without scram (ATWS)

  3. Numerical simulation of white double-layer coating with different submicron particles on the spectral reflectance

    International Nuclear Information System (INIS)

    Chai, Jiale; Cheng, Qiang; Si, Mengting; Su, Yang; Zhou, Yifan; Song, Jinlin

    2017-01-01

    The spectral selective coating is becoming more and more popular against solar irradiation not only in keeping the coated objects stay cool but also retain the appearance of the objects by reducing the glare of reflected sunlight. In this work a numerical study is investigated to design the double-layer coating with different submicron particles to achieve better performance both in thermal and aesthetic aspects. By comparison, the performance of double-layer coating with TiO_2 and ZnO particles is better than that with single particles. What's more, the particle diameter, volume fraction of particle as well as substrate condition is also investigated. The results show that an optimized double-layer coating with particles should be the one with an appropriate particle diameter, volume fraction and the black substrate. - Highlights: • The double-layer coating has a great influence on both thermal and aesthetic aspects. • The double-layer coating performs better than the uniform one with single particles. • The volume fraction, particle diameter and substrate conditions are optimized.

  4. "Attitude is a little thing that makes a big difference": reflection techniques for addiction psychiatry training.

    Science.gov (United States)

    Ballon, Bruce C; Skinner, Wayne

    2008-01-01

    The authors aim to incorporate educational reflection techniques in an addiction psychiatry postgraduate core rotation in order to increase critical self-awareness of attitudes, values, and beliefs related to working with people with substance use and other addictive disorders. Reflection discussion times, reflection journaling, and mandatory end-of-rotation reflection papers were embedded into a core addiction psychiatry postgraduate training block. Qualitative analysis of 28 reflection papers was performed to determine key factors and constructs that impacted on the development of attitudes and professionalism. A number of constructs emerged that demonstrated the attitudes, beliefs, stereotypes, and stigmas students have regarding addictive disorders. Some constructs also highlighted that students felt much more comfortable dealing with addictive disorders after the training and would treat individuals with these conditions in a more effective manner. Reflection techniques were endorsed as extremely valuable by students, especially in the development of professional attitudes that will help clinicians effectively engage and provide appropriate care for individuals suffering from addictive disorders. The authors suggest that reflective practices be used more extensively in psychiatric training in order to build and establish reflexive self-awareness as a core professional competence essential to work effectively in clinical practice, especially in the most demanding contexts.

  5. Inherently safe in situ uranium recovery

    International Nuclear Information System (INIS)

    Krumhansl, James Lee; Beauheim, Richard Louis; Brady, Patrick Vane; Arnold, Bill Walter; Kanney, Joseph F.; McKenna, Sean Andrew

    2009-01-01

    Expansion of uranium mining in the United States is a concern to some environmental groups and sovereign Native American Nations. An approach which may alleviate some problems is to develop inherently safe in situ uranium recovery ('ISR') technologies. Current ISR technology relies on chemical extraction of trace levels of uranium from aquifers that, once mined, can still contain dissolved uranium and other trace metals that are a health concern. Existing ISR operations are few in number; however, high uranium prices are driving the industry to consider expanding operations nation-wide. Environmental concerns and enforcement of the new 30 ppb uranium drinking water standard may make opening new mining operations more difficult and costly. Here we propose a technological fix: the development of inherently safe in situ recovery (ISISR) methods. The four central features of an ISISR approach are: (1) New 'green' leachants that break down predictably in the subsurface, leaving uranium, and associated trace metals, in an immobile form; (2) Post-leachant uranium/metals-immobilizing washes that provide a backup decontamination process; (3) An optimized well-field design that increases uranium recovery efficiency and minimizes excursions of contaminated water; and (4) A combined hydrologic/geochemical protocol for designing low-cost post-extraction long-term monitoring. ISISR would bring larger amounts of uranium to the surface, leave fewer toxic metals in the aquifer, and cost less to monitor safely - thus providing a 'win-win-win' solution to all stakeholders.

  6. A fit method for the determination of inherent filtration with diagnostic x-ray units

    International Nuclear Information System (INIS)

    Meghzifene, K; Nowotny, R; Aiginger, H

    2006-01-01

    A method for the determination of total inherent filtration for clinical x-ray units using attenuation curves was devised. A model for the calculation of x-ray spectra is used to calculate kerma values which are then adjusted to the experimental data in minimizing the sum of the squared relative differences in kerma using a modified simplex fit process. The model considers tube voltage, voltage ripple, anode angle and additional filters. Fit parameters are the thickness of an additional inherent Al filter and a general normalization factor. Nineteen sets of measurements including attenuation data for three tube voltages and five Al-filter settings each were obtained. Relative differences of experimental and calculated kerma using the data for the additional filter thickness are within a range of -7.6% to 6.4%. Quality curves, i.e. the relationship of additional filtration to HVL, are often used to determine filtration but the results show that standard quality curves do not reflect the variety of conditions encountered in practice. To relate the thickness of the additional filter to the condition of the anode surface, the data fits were also made using tungsten as the filter material. These fits gave an identical fit quality compared to aluminium with a tungsten filter thickness of 2.12-8.21 μm which is within the range of the additional absorbing layers determined for rough anodes

  7. The inherent limits of predicting school violence.

    Science.gov (United States)

    Mulvey, E P; Cauffman, E

    2001-10-01

    The recent media hype over school shootings has led to demands for methods of identifying school shooters before they act. Despite the fact that schools remain one of the safest places for youths to be, schools are beginning to adopt identification systems to determine which students could be future killers. The methods used to accomplish this not only are unproven but are inherently limited in usefulness and often do more harm than good for both the children and the school setting. The authors' goals in the present article are to place school shootings in perspective relative to other risks of violence that children face and to provide a reasonable and scientifically defensible approach to improving the safety of schools.

  8. Inherent Error in Asynchronous Digital Flight Controls.

    Science.gov (United States)

    1980-02-01

    operation will be eliminated. If T* is close to T, the inherent error (eA) is a small value. Then the deficiency of the basic model, which is de... tK2 at m ~VCONTR0RKIPPIL I~+ R tKT 2 TKT 5 ~I G E 1 i V OTN TRIL 2-REDN HNE IjT e UT 3 ~49__I 4.) 4 -4 - 4.-4 U 4.) k-4E-- Iz E-4 P E-44)-4. 4.)l 1s...indicate the channel failure. To reduce this deficiency , the new model computes a tolerance value equal to the maximum steady-state sample covariance of the

  9. Inherently safe in situ uranium recovery

    Science.gov (United States)

    Krumhansl, James L; Brady, Patrick V

    2014-04-29

    An in situ recovery of uranium operation involves circulating reactive fluids through an underground uranium deposit. These fluids contain chemicals that dissolve the uranium ore. Uranium is recovered from the fluids after they are pumped back to the surface. Chemicals used to accomplish this include complexing agents that are organic, readily degradable, and/or have a predictable lifetime in an aquifer. Efficiency is increased through development of organic agents targeted to complexing tetravalent uranium rather than hexavalent uranium. The operation provides for in situ immobilization of some oxy-anion pollutants under oxidizing conditions as well as reducing conditions. The operation also artificially reestablishes reducing conditions on the aquifer after uranium recovery is completed. With the ability to have the impacted aquifer reliably remediated, the uranium recovery operation can be considered inherently safe.

  10. Magnetic latch trigger for inherent shutdown assembly

    International Nuclear Information System (INIS)

    Sowa, E.S.

    1976-01-01

    An inherent shutdown assembly for a nuclear reactor is provided. A neutron absorber is held ready to be inserted into the reactor core by a magnetic latch. The latch includes a magnet whose lines of force are linked by a yoke of material whose Curie point is at the critical temperature of the reactor at which the neutron absorber is to be inserted into the reactor core. The yoke is in contact with the core coolant or fissionable material so that when the coolant or the fissionable material increase in temperature above the Curie point the yoke loses its magnetic susceptibility and the magnetic link is broken, thereby causing the absorber to be released into the reactor core. 6 claims, 3 figures

  11. Inherent safety characteristics of innovative reactors

    International Nuclear Information System (INIS)

    Heil, J.A.

    1995-11-01

    The added safety value of innovative or third generation reactor designs has been evaluated in order to determine the most suitable candidate for Dutch government funded research and development support. To this end, four innovative reactor concepts, viz. PIUS (Process Inherent Ultimate Safety), PRISM (Power Reactor Innovative Small), HTR-M (High Temperature Reactor Module) and MHTGR (Modular High Temperature Gas-cooled Reactor), have been studied and their passive and inherent safety characteristics have been outlined. Also the outlook for further technological and industrial development has been considered. The results of the study confirm the perspective of the innovative reactors for reduced dependence on active safety provisions and for a further reduced vulnerability to technical failures and human errors. The accident responses to generic accident initiators, viz. reactivity and cooling accidents, and also to reactor specific accidents show that neither active safety systems nor short term operator actions are required for maintaining the reactor core in a controlled and coolable condition. Whether this gives rise to a higher total safety of the innovative reactor designs, compared to evolutionary or advanced reactors, cannot be concluded. Supplementary experimental and analytical analyses of reactor specific accidents are required to be able to assess the safety of these innovative designs in a more quantitative manner. It is believed that the safety case of innovative reactors, which are less dependent on active safety systems, can be communicated with the general public in a more transparent way. Considering the perspective for further technological and industrial development it is not expected that any of the considered innovative reactor concepts will become commercially available within the next one to two decades. However, they could be made available earlier if they would receive sufficient financial backing. Considering the added safety perspectives

  12. Metacognitive ability of male students: difference impulsive-reflective cognitive style

    Science.gov (United States)

    Muhtarom; Sugiyanti; Utami, R. E.; Indriana, K.

    2018-03-01

    This study revealed the metacognitive activity of male students in impulsive cognitive and reflective cognitive style in solving mathematical problems, especially in the material of plane. One student of impulsive cognitive style and one student of reflective cognitive-style were selected to be the subjects of the study. Data were collected by giving written test of problem solving and interview. Data analysis was done through data reduction, data presentation, data interpretation and conclusion. The results showed that male student of reflective cognitive style was meticulous and careful in solving the problem so as to obtain correct answers, while the impulsive cognitive style student had the characteristics of using a short time in solving the problem, but less careful so that the answers tended to be wrong

  13. Conservation Through Different Lenses: Reflection, Responsibility, and the Politics of Participation in Conservation Advocacy

    Science.gov (United States)

    Abrash Walton, Abigail

    2010-01-01

    This essay considers the arenas of advocacy, politics, and self-reflection in strengthening conservation and resource management initiatives. It frames key questions that reflective conservation practitioners may address in seeking to enhance the results of conservation projects, including equity and more inclusive participation by nonprivileged groups. The essay touches on the importance of understanding conservation work within particular political and historic dynamics, including the need to understand non-Western and/or indigenous or traditional perspectives on conservation. The author makes the case that Western or privileged conservation practitioners are uniquely situated to advocate effectively for change.

  14. Effects of irradiation conditions and environment on the reflectivity of different steel mirrors for ITER diagnostics systems

    International Nuclear Information System (INIS)

    Hernandez, Teresa; Martin, Piedad; Fernandez, Pilar; Hodgson, Eric R.

    2009-01-01

    In this work possible degradation of the reflectivity for mirrors made from various steels subjected to ionizing radiation, at moderate temperature and in different environments (vacuum, air, or nitrogen) up to a total dose of 9 MGy, has been examined. Mirrors were prepared from conventional austenitic stainless steel (316L) and also reduced activation ferritic/martensitic (RAFM) steels (Eurofer, ODS-Eurofer, F82H), and the reflectivity studied from ultraviolet to near infrared, before and after different treatments. Under all conditions the austenitic steel mirrors only degrade slightly (<10%), however for the reduced activation steels important reflectivity degradation for wavelengths below 1000 nm are observed for the different conditions. Surface morphology and microstructure has been also investigated using scanning electron microscopy (SEM). The production of near surface nitrides is considered to be the possible cause of the optical degradation.

  15. Ordeals of Chernobyl and the rejustification of the inherently safe reactors

    International Nuclear Information System (INIS)

    Lu, Y.

    1989-01-01

    This paper presents the necessity of developing inherently safe economic reactors (ISERs). Two characteristics which define inherent safety are discussed on the basis of various applications of such a principle in practice. Different design concepts of ISERs are then evaluated and their possible role in the future nuclear program of PRC discussed. A three-stage development strategy of ISERs in PRC is proposed

  16. Reflectance-difference spectroscopy as an optical probe for in situ determination of doping levels in GaAs

    Energy Technology Data Exchange (ETDEWEB)

    Lastras-Martinez, A.; Lara-Velazquez, I.; Balderas-Navarro, R.E.; Ortega-Gallegos, J.; Guel-Sandoval, S.; Lastras-Martinez, L.F. [Instituto de Investigacion en Comunicacion Optica, Universidad Autonoma de San Luis Potosi, Alvaro Obregon 64, San Luis Potosi, SLP 78000 (Mexico)

    2008-07-01

    We report on in situ Reflectance Difference Spectroscopy measurements carried out on GaAs(001). Measurements were performed at temperatures of 580 C and 430 C, in both n and p-type doped films and for both (2 x 4) and c(4 x 4) reconstructions. Samples employed were grown by Molecular Beam Epitaxy with doping levels in the range from 10{sup 16}-10{sup 19} cm{sup -3}. We demonstrate the potential of Reflectance Difference Spectroscopy for impurity level determinations under growth conditions. (copyright 2008 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  17. Conceptual design of inherently safe integral reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J. I.; Chang, M. H.; Lee, D. J. and others

    1999-03-01

    The design concept of a 300 MWt inherently safe integral reactor(ISIR) for the propulsion of extra large and superhigh speed container ship was developed in this report. The scope and contents of this report are as follows : 1. The state of the art of the technology for ship-mounted reactor 2. Design requirements for ISIR 3. Fuel and core design 4. Conceptual design of fluid system 5. Conceptual design of reactor vessel assembly and primary components 6. Performance analyses and safety analyses. Installation of two ISIRs with total thermal power of 600MWt and efficiency of 21% is capable of generating shaft power of 126,000kW which is sufficient to power a container ship of 8,000TEU with 30knot cruise speed. Larger and speedier ship can be considered by installing 4 ISIRs. Even though the ISIR was developed for ship propulsion, it can be used also for a multi-purpose nuclear power plant for electricity generation, local heating, or seawater desalination by mounting on a movable floating barge. (author)

  18. The Inherent Asymmetry of DNA Replication.

    Science.gov (United States)

    Snedeker, Jonathan; Wooten, Matthew; Chen, Xin

    2017-10-06

    Semiconservative DNA replication has provided an elegant solution to the fundamental problem of how life is able to proliferate in a way that allows cells, organisms, and populations to survive and replicate many times over. Somewhat lost, however, in our admiration for this mechanism is an appreciation for the asymmetries that occur in the process of DNA replication. As we discuss in this review, these asymmetries arise as a consequence of the structure of the DNA molecule and the enzymatic mechanism of DNA synthesis. Increasing evidence suggests that asymmetries in DNA replication are able to play a central role in the processes of adaptation and evolution by shaping the mutagenic landscape of cells. Additionally, in eukaryotes, recent work has demonstrated that the inherent asymmetries in DNA replication may play an important role in the process of chromatin replication. As chromatin plays an essential role in defining cell identity, asymmetries generated during the process of DNA replication may play critical roles in cell fate decisions related to patterning and development.

  19. Improved inherent safety in liquid fuel reactors

    International Nuclear Information System (INIS)

    Taube, M.

    1982-01-01

    The molten salt reactor system divided into core (thermal and fast) and breeding zone (fission breeder reactor, fusion hybrid system, accelerator-spallation system) has some unique inherent safety properties: a) reduced inventory of fission products during normal operation due to on-line chemical reprocessing and in-core gas purging; b) fast removal of freshly bred fissile nuclides and fission products from the breeding zone (the so called suppressed fission system); c) pressureless fuel and primary coolant system; d) elimination of the possibility of a violent exoenergetic chemical reaction with air, water or metals; e) elimination of the possibility of gaseous hydrogen production during an accident; f) provides a non-engineered feature of dumping of fuel from the core and heat exchanger to a safe drain tank; g) presence of a large heat sink in the form of an inactive diluent salt; h) possibility of natural convection heat removal during an accident and even normal operation (by means of gas lifting); i) dissipation of the remaining decayheat by spraying water on the containment from outside, which allows to manage the worst accident; i) Even in the case of the destruction in the war by conventional or nuclear weapon the contaminated land is significantly reduced. The world-wide present activity in the field of molten salt technology is reviewed. (orig.)

  20. Bifurcation parameters of a reflected shock wave in cylindrical channels of different roughnesses

    Science.gov (United States)

    Penyazkov, O.; Skilandz, A.

    2018-03-01

    To investigate the effect of bifurcation on the induction time in cylindrical shock tubes used for chemical kinetic experiments, one should know the parameters of the bifurcation structure of a reflected shock wave. The dynamics and parameters of the shock wave bifurcation, which are caused by reflected shock wave-boundary layer interactions, are studied experimentally in argon, in air, and in a hydrogen-nitrogen mixture for Mach numbers M = 1.3-3.5 in a 76-mm-diameter shock tube without any ramp. Measurements were taken at a constant gas density behind the reflected shock wave. Over a wide range of experimental conditions, we studied the axial projection of the oblique shock wave and the pressure distribution in the vicinity of the triple Mach configuration at 50, 150, and 250 mm from the endwall, using side-wall schlieren and pressure measurements. Experiments on a polished shock tube and a shock tube with a surface roughness of 20 {μ }m Ra were carried out. The surface roughness was used for initiating small-scale turbulence in the boundary layer behind the incident shock wave. The effect of small-scale turbulence on the homogenization of the transition zone from the laminar to turbulent boundary layer along the shock tube perimeter was assessed, assuming its influence on a subsequent stabilization of the bifurcation structure size versus incident shock wave Mach number, as well as local flow parameters behind the reflected shock wave. The influence of surface roughness on the bifurcation development and pressure fluctuations near the wall, as well as on the Mach number, at which the bifurcation first develops, was analyzed. It was found that even small additional surface roughness can lead to an overshoot in pressure growth by a factor of two, but it can stabilize the bifurcation structure along the shock tube perimeter.

  1. Inherent uncertainties in meteorological parameters for wind turbine design

    Science.gov (United States)

    Doran, J. C.

    1982-01-01

    Major difficulties associated with meteorological measurments such as the inability to duplicate the experimental conditions from one day to the next are discussed. This lack of consistency is compounded by the stochastic nature of many of the meteorological variables of interest. Moreover, simple relationships derived in one location may be significantly altered by topographical or synoptic differences encountered at another. The effect of such factors is a degree of inherent uncertainty if an attempt is made to describe the atmosphere in terms of universal laws. Some of these uncertainties and their causes are examined, examples are presented and some implications for wind turbine design are suggested.

  2. Sparkling feather reflections of a bird-of-paradise explained by finite-difference time-domain modeling.

    Science.gov (United States)

    Wilts, Bodo D; Michielsen, Kristel; De Raedt, Hans; Stavenga, Doekele G

    2014-03-25

    Birds-of-paradise are nature's prime examples of the evolution of color by sexual selection. Their brilliant, structurally colored feathers play a principal role in mating displays. The structural coloration of both the occipital and breast feathers of the bird-of-paradise Lawes' parotia is produced by melanin rodlets arranged in layers, together acting as interference reflectors. Light reflection by the silvery colored occipital feathers is unidirectional as in a classical multilayer, but the reflection by the richly colored breast feathers is three-directional and extraordinarily complex. Here we show that the reflection properties of both feather types can be quantitatively explained by finite-difference time-domain modeling using realistic feather anatomies and experimentally determined refractive index dispersion values of keratin and melanin. The results elucidate the interplay between avian coloration and vision and indicate tuning of the mating displays to the spectral properties of the avian visual system.

  3. Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture

    DEFF Research Database (Denmark)

    Enattah, Nabil Sabri; Jensen, Tine G K; Boyd, Mette

    2008-01-01

    the same history, probably related to the same cattle domestication event. In contrast, the compound Arab allele shows a different, highly divergent ancestral haplotype, suggesting that these two major global LP alleles have arisen independently, the latter perhaps in response to camel milk consumption....... These results support the convergent evolution of the LP in diverse populations, most probably reflecting different histories of adaptation to milk culture....

  4. In situ differential reflectance spectroscopy of thin crystalline films of PTCDA on different substrates

    International Nuclear Information System (INIS)

    Proehl, Holger; Nitsche, Robert; Dienel, Thomas; Leo, Karl; Fritz, Torsten

    2005-01-01

    We report an investigation of the excitonic properties of thin crystalline films of the archetypal organic semiconductor PTCDA (3,4,9,10-perylenetetracarboxylic dianhydride) grown on poly- and single crystalline surfaces. A sensitive setup capable of measuring the optical properties of ultrathin organic molecular crystals via differential reflectance spectroscopy (DRS) is presented. This tool allows to carry out measurements in situ, i.e., during the actual film growth, and over a wide spectral range, even on single crystalline surfaces with high symmetry or metallic surfaces, where widely used techniques like reflection anisotropy spectroscopy (RAS) or fluorescence excitation spectroscopy fail. The spectra obtained by DRS resemble mainly the absorption of the films if transparent substrates are used, which simplifies the analysis. In the case of mono- to multilayer films of PTCDA on single crystalline muscovite mica(0001) and Au(111) substrates, the formation of the solid state absorption from monomer to dimer and further to crystal-like absorption spectra can be monitored

  5. Sex Differences in White Matter Microstructure in the Human Brain Predominantly Reflect Differences in Sex Hormone Exposure

    NARCIS (Netherlands)

    van Hemmen, J; Saris, I M J; Cohen-Kettenis, P T; Veltman, D J; Pouwels, P J W; Bakker, J

    Sex differences have been described regarding several aspects of human brain morphology; however, the exact biological mechanisms underlying these differences remain unclear in humans. Women with the complete androgen insensitivity syndrome (CAIS), who lack androgen action in the presence of a 46,XY

  6. Inherent/passive safety in fusion power plants

    International Nuclear Information System (INIS)

    Piet, S.J.; Crocker, J.G.

    1986-01-01

    The concept of inherent or passive safety for fusion energy is explored, defined, and partially quantified. Four levels of safety assurance are defined, which range from true inherent safety to passive safety to protection via active engineered safeguard systems. Fusion has the clear potential for achieving inherent or passive safety, which should be an objective of fusion research and design. Proper material choice might lead to both inherent/passive safety and high mass power density, improving both safety and economics. When inherent or passive safety is accomplished, fusion will be well on the way to achieving its ultimate potential and to be a truly superior energy source for the future

  7. On the Eastern and Western Cultures as Reflected in Differences in Food Culture

    Institute of Scientific and Technical Information of China (English)

    黄卓; 张海南

    2015-01-01

    When talking about differences between Eastern and Western culture,we should first think of the eating cultural differences.There are many differences in Eastern and Western food cultures,in this paper it will introduce the different food concepts,the different eating goals,the different eating habits,etc.A comparison study of Chinese and Western food culture still makes sense through the analysis of cultural differences between Chinese and Western food,we can understand their own cultural traditions in China and the West.At the same time it is able to carry out improvement and innovation of Chinese culture.Throughout the comparisons,coupled with the differences of the concept of Western food culture,objects,methods,ownership and nature,it studies these differences,identifies areas for mastery of the place,promotes cultural exchange.Thus it enables China to the world,and to make the world know China better.

  8. On the Eastern and Western Cultures as Reflected in Differences in Food Culture

    Institute of Scientific and Technical Information of China (English)

    黄卓; 张海南

    2015-01-01

    When talking about differences between Eastern and Western culture,we should first think of the eating cultural differences.There are many differences in Eastern and Western food cultures,in this paper it will introduce the different food concepts,the different eating goals,the different eating habits,etc. A comparison study of Chinese and Western food culture still makes sense through the analysis of cultural differences between Chinese and Western food,we can understand their own cultural traditions in China and the West.At the same time it is able to carry out improvement and innovation of Chinese culture. Throughout the comparisons,coupled with the differences of the concept of Western food culture,objects,methods,ownership and nature,it studies these differences,identifies areas for mastery of the place,promotes cultural exchange.Thus it enables China to the world,and to make the world know China better.

  9. The inherent inefficiency of simultaneously feasible financial transmission rights auctions

    International Nuclear Information System (INIS)

    Deng, Shi-Jie; Oren, Shmuel; Meliopoulos, A.P.

    2010-01-01

    Empirical evidence from the New York ISO shows that the clearing prices for point-to-point congestion revenue rights, also known as financial transmission rights (FTRs), resulting from centralized auctions conducted by Independent System Operators differ significantly and systematically from the realized congestion revenues that determine the accrued payoffs of these rights. The question addressed by this paper is whether such deviations are due to price discovery errors which will eventually vanish or due to inherent inefficiencies in the auction structure. We show that even with perfect foresight of average congestion rents the clearing prices for the FTRs depend on the bid quantity and therefore may not be priced correctly in the financial transmission right (FTR) auction. In particular, we prove that quantity limits on the FTR bids may cause the auction clearing prices to differ from the bid prices. This phenomenon which is inherent in the theoretical properties of the optimization algorithm used to clear the auction, is further illustrated through numerical simulations with test systems. We conclude that price discovery alone would not remedy the discrepancy between the auction prices and the realized values of the FTRs. Secondary markets or frequent reconfiguration auctions are necessary in order to achieve such convergence. (author)

  10. Individual Differences in Numeracy and Cognitive Reflection, with Implications for Biases and Fallacies in Probability Judgment

    NARCIS (Netherlands)

    J.M. Liberali (Jordana ); V.F. Reyna (Valerie ); S. Furlan (Sarah); L.M. Stein (Lilian ); S.T. Pardo (Seth )

    2012-01-01

    textabstractDespite evidence that individual differences in numeracy affect judgment and decision making, the precise mechanisms underlying how such differences produce biases and fallacies remain unclear. Numeracy scales have been developed without sufficient theoretical grounding, and their

  11. Anatomically discrete sex differences in neuroplasticity in zebra finches as reflected by perineuronal nets

    NARCIS (Netherlands)

    Cornez, Gilles; ter Haar, Sita M; Cornil, Charlotte A; Balthazart, Jacques

    2015-01-01

    Large morphological sex differences in the vertebrate brain were initially identified in song control nuclei of oscines. Besides gross differences between volumes of nuclei in males and females, sex differences also concern the size and dendritic arborization of neurons and various neurochemical

  12. The Minimum Data Set Depression Quality Indicator: Does It Reflect Differences in Care Processes?

    Science.gov (United States)

    Simmons, S.F.; Cadogan, M.P.; Cabrera, G.R.; Al-Samarrai, N.R.; Jorge, J.S.; Levy-Storms, L.; Osterweil, D.; Schnelle, J.F.

    2004-01-01

    Purpose. The objective of this work was to determine if nursing homes that score differently on prevalence of depression, according to the Minimum Data Set (MDS) quality indicator, also provide different processes of care related to depression. Design and Methods. A cross-sectional study with 396 long-term residents in 14 skilled nursing…

  13. Drug policy in sport: hidden assumptions and inherent contradictions.

    Science.gov (United States)

    Smith, Aaron C T; Stewart, Bob

    2008-03-01

    This paper considers the assumptions underpinning the current drugs-in-sport policy arrangements. We examine the assumptions and contradictions inherent in the policy approach, paying particular attention to the evidence that supports different policy arrangements. We find that the current anti-doping policy of the World Anti-Doping Agency (WADA) contains inconsistencies and ambiguities. WADA's policy position is predicated upon four fundamental principles; first, the need for sport to set a good example; secondly, the necessity of ensuring a level playing field; thirdly, the responsibility to protect the health of athletes; and fourthly, the importance of preserving the integrity of sport. A review of the evidence, however, suggests that sport is a problematic institution when it comes to setting a good example for the rest of society. Neither is it clear that sport has an inherent or essential integrity that can only be sustained through regulation. Furthermore, it is doubtful that WADA's anti-doping policy is effective in maintaining a level playing field, or is the best means of protecting the health of athletes. The WADA anti-doping policy is based too heavily on principals of minimising drug use, and gives insufficient weight to the minimisation of drug-related harms. As a result drug-related harms are being poorly managed in sport. We argue that anti-doping policy in sport would benefit from placing greater emphasis on a harm minimisation model.

  14. An assimilation test of Doppler radar reflectivity and radial velocity from different height layers in improving the WRF rainfall forecasts

    Science.gov (United States)

    Tian, Jiyang; Liu, Jia; Yan, Denghua; Li, Chuanzhe; Chu, Zhigang; Yu, Fuliang

    2017-12-01

    Hydrological forecasts require high-resolution and accurate rainfall information, which is one of the most difficult variables to be captured by the mesoscale Numerical Weather Prediction (NWP) systems. Radar data assimilation is an effective method for improving rainfall forecasts by correcting the initial and lateral boundary conditions of the NWP system. The aim of this study is to explore an efficient way of utilizing the Doppler radar observations for data assimilation, which is implemented by exploring the effect of assimilating radar data from different height layers on the improvement of the NWP rainfall accuracy. The Weather Research and Forecasting (WRF) model is used for numerical rainfall forecast in the Zijingguan catchment located in the ;Jing-Jin-Ji; (Beijing-Tianjin-Hebei) Region of Northern China, and the three-dimensional variational data assimilation (3-DVar) technique is adopted to assimilate the radar data. Radar reflectivity and radial velocity are assimilated separately and jointly. Each type of radar data is divided into seven data sets according to the height layers: (1) 2000 m, and (7) all layers. The results show that radar reflectivity assimilation leads to better results than radial velocity assimilation. The accuracy of the forecasted rainfall deteriorates with the rise of the height of the assimilated radar reflectivity. The same results can be found when assimilating radar reflectivity and radial velocity at the same time. The conclusions of this study provide a reference for efficient assimilation of the radar data in improving the NWP rainfall products.

  15. The inherently-safe power reactor DYONISOS (Dynamic Nuclear Inherently-Safe Reactor Operating with Spheres)

    International Nuclear Information System (INIS)

    Taube, M.; Lanfranchi, M.; Weissenfluh, Th. von; Ligou, J.; Yadigaroglu, G.; Taube, P.

    1986-01-01

    A philosophy of inherent safety is formulated and an inherently-safe thermal power reactor is presented. Solid fuel in the form of spheres a few centimetres in diameter is suspended under the hydro-dynamic pressure of molten lead coolant in vertical channels within the graphite moderator. Loss of main pump pressure, or a loss-of-coolant accident (LOCA), results in immediate removal of the fuel to rigid sieves below the core, with consequent subcriticality. Residual and decay heat are carried away by thermal conduction through the coolant or, in the case of a LOCA, by a combination of radiation and natural convection of cover gas or incoming air from the fuel to the reactor vessel and convection of air between the vessel and steel containment wall. All decay heat removal systems are passive, though actively initiated external spray cooling of the containment can be used to reduce wall temperature. This, however, is only necessary in the case of a LOCA and after a period of 24 h. (author)

  16. Response time in economic games reflects different types of decision conflict for prosocial and proself individuals.

    Science.gov (United States)

    Yamagishi, Toshio; Matsumoto, Yoshie; Kiyonari, Toko; Takagishi, Haruto; Li, Yang; Kanai, Ryota; Sakagami, Masamichi

    2017-06-13

    Behavioral and neuroscientific studies explore two pathways through which internalized social norms promote prosocial behavior. One pathway involves internal control of impulsive selfishness, and the other involves emotion-based prosocial preferences that are translated into behavior when they evade cognitive control for pursuing self-interest. We measured 443 participants' overall prosocial behavior in four economic games. Participants' predispositions [social value orientation (SVO)] were more strongly reflected in their overall game behavior when they made decisions quickly than when they spent a longer time. Prosocially (or selfishly) predisposed participants behaved less prosocially (or less selfishly) when they spent more time in decision making, such that their SVO prosociality yielded limited effects in actual behavior in their slow decisions. The increase (or decrease) in slower decision makers was prominent among consistent prosocials (or proselfs) whose strong preference for prosocial (or proself) goals would make it less likely to experience conflict between prosocial and proself goals. The strong effect of RT on behavior in consistent prosocials (or proselfs) suggests that conflict between prosocial and selfish goals alone is not responsible for slow decisions. Specifically, we found that contemplation of the risk of being exploited by others (social risk aversion) was partly responsible for making consistent prosocials (but not consistent proselfs) spend longer time in decision making and behave less prosocially. Conflict between means rather than between goals (immediate versus strategic pursuit of self-interest) was suggested to be responsible for the time-related increase in consistent proselfs' prosocial behavior. The findings of this study are generally in favor of the intuitive cooperation model of prosocial behavior.

  17. Exercises Abroad: How Differing National Experiences are Reflected in Emergency Response Planning and Exercises

    International Nuclear Information System (INIS)

    Marianno, Craig

    2007-01-01

    Recently a member of the U.S. Department of Energy's (DOE) Consequence Management Response Team took part in outreaches and an exercise in different foreign countries. In Brazil and South Korea, the outreaches revolved around a nuclear power plant exercise. In Canada, participation was limited to a table top Consequence Management exercise. This talk will briefly discuss each event and resulting pertinent observations. In each case, it became evident that governments respond to disasters very differently, and that these differences are not only culturally based, but also influenced by each government's respective experience in dealing with natural disasters

  18. Proteomic response of Bacillus subtilis to lantibiotics reflects differences in interaction with the cytoplasmic membrane

    NARCIS (Netherlands)

    Wenzel, M.; Kohl, B.; Münch, D.; Raatschen, N.; Albada, H.B.; Hamoen, L.; Metzler-Nolte, N.; Sahl, H.G.; Bandow, J.E.

    2012-01-01

    Mersacidin, gallidermin, and nisin are lantibiotics, antimicrobial peptides containing lanthionine. They show potent antibacterial activity. All three interfere with cell wall biosynthesis by binding lipid II, but they display different levels of interaction with the cytoplasmic membrane. On one end

  19. Multiple Antenna Systems with Inherently Decoupled Radiators

    DEFF Research Database (Denmark)

    Pelosi, Mauro; Knudsen, Mikael B.; Pedersen, Gert Frølund

    2012-01-01

    In multiple antenna systems mutual coupling needs to be minimized. We propose an alternative novel decoupling technique, investigating several multiple antenna configurations for small handsets through measurements and numerical simulations. The influence of different novel designs on performance...... metrics such as total loss, antenna isolation and envelope correlation coefficient are investigated. By varying antenna impedance bandwidth and antenna location with respect to the handset, both Planar Inverted F Antenna (PIFA) and Inverted F Antennas (IFA) were investigated in different UMTS frequency...

  20. Through Solidarity to "Fluidarity": Understanding Difference and Developing Change Agency through Narrative Reflection

    Science.gov (United States)

    Maruggi, Matthew

    2012-01-01

    This paper examines the development of the concept of solidarity as expressing a sense of shared humanity, while detailing critiques of its current use, especially when it implies a privileged center setting the agenda for the sake of marginalized others. My research demonstrates how solidarity can be modified when encountering difference, and how…

  1. Different Oceanographic Regimes in the Vicinity of the Antarctic Peninsula Reflected in Benthic Nematode Communities.

    Directory of Open Access Journals (Sweden)

    Freija Hauquier

    Full Text Available Marine free-living nematode communities were studied at similar depths (~500 m at two sides of the Antarctic Peninsula, characterised by different environmental and oceanographic conditions. At the Weddell Sea side, benthic communities are influenced by cold deep-water formation and seasonal sea-ice conditions, whereas the Drake Passage side experiences milder oceanic conditions and strong dynamics of the Antarctic Circumpolar Current. This resulted in different surface primary productivity, which contrasted with observed benthic pigment patterns and varied according to the area studied: chlorophyll a concentrations (as a proxy for primary production were high in the Weddell Sea sediments, but low in the surface waters above; this pattern was reversed in the Drake Passage. Differences between areas were largely mirrored by the nematode communities: nematode densities peaked in Weddell stations and showed deeper vertical occurrence in the sediment, associated with deeper penetration of chlorophyll a and indicative of a strong bentho-pelagic coupling. Generic composition showed some similarities across both areas, though differences in the relative contribution of certain genera were noted, together with distinct community shifts with depth in the sediment at all locations.

  2. Are population differences in plant quality reflected in the preference and performance of two endoparasitoid wasps?

    NARCIS (Netherlands)

    Gols, R.; Dam, van N.M.; Raaijmakers, C.E.; Dicke, M.; Harvey, J.A.

    2009-01-01

    In recent years, increasing attention has been paid in exploring the role of direct plant defence, through the production of allelochemicals, on the performance of parasitoid wasps and their hosts. However, few studies have determined if parasitoids can detect differences in plant quality and thus

  3. Personality-dependent differences in problem-solving performance in a social context reflect foraging strategies

    NARCIS (Netherlands)

    Zandberg, Lies; Quinn, John L.; Naguib, Marc; van Oers, Kees

    2017-01-01

    Abstract Individuals develop innovative behaviours to solve foraging challenges in the face of changing environmental conditions. Little is known about how individuals differ in their tendency to solve problems and in their subsequent use of this solving behaviour in social contexts. Here we

  4. Personality-dependent differences in problem-solving performance in a social context reflect foraging strategies

    NARCIS (Netherlands)

    Zandberg, Lies; Quinn, John L.; Naguib, Marc; Oers, Van Kees

    2016-01-01

    Individuals develop innovative behaviours to solve foraging challenges in the face of changing environmental conditions. Little is known about how individuals differ in their tendency to solve problems and in their subsequent use of this solving behaviour in social contexts. Here we investigated

  5. Individual Differences in Temporal Selective Attention as Reflected in Pupil Dilation.

    Directory of Open Access Journals (Sweden)

    Charlotte Willems

    Full Text Available Attention is restricted for the second of two targets when it is presented within 200-500 ms of the first target. This attentional blink (AB phenomenon allows one to study the dynamics of temporal selective attention by varying the interval between the two targets (T1 and T2. Whereas the AB has long been considered as a robust and universal cognitive limitation, several studies have demonstrated that AB task performance greatly differs between individuals, with some individuals showing no AB whatsoever.Here, we studied these individual differences in AB task performance in relation to differences in attentional timing. Furthermore, we investigated whether AB magnitude is predictive for the amount of attention allocated to T1. For both these purposes pupil dilation was measured, and analyzed with our recently developed deconvolution method. We found that the dynamics of temporal attention in small versus large blinkers differ in a number of ways. Individuals with a relatively small AB magnitude seem better able to preserve temporal order information. In addition, they are quicker to allocate attention to both T1 and T2 than large blinkers. Although a popular explanation of the AB is that it is caused by an unnecessary overinvestment of attention allocated to T1, a more complex picture emerged from our data, suggesting that this may depend on whether one is a small or a large blinker.The use of pupil dilation deconvolution seems to be a powerful approach to study the temporal dynamics of attention, bringing us a step closer to understanding the elusive nature of the AB. We conclude that the timing of attention to targets may be more important than the amount of allocated attention in accounting for individual differences.

  6. Individual Differences in Temporal Selective Attention as Reflected in Pupil Dilation.

    Science.gov (United States)

    Willems, Charlotte; Herdzin, Johannes; Martens, Sander

    2015-01-01

    Attention is restricted for the second of two targets when it is presented within 200-500 ms of the first target. This attentional blink (AB) phenomenon allows one to study the dynamics of temporal selective attention by varying the interval between the two targets (T1 and T2). Whereas the AB has long been considered as a robust and universal cognitive limitation, several studies have demonstrated that AB task performance greatly differs between individuals, with some individuals showing no AB whatsoever. Here, we studied these individual differences in AB task performance in relation to differences in attentional timing. Furthermore, we investigated whether AB magnitude is predictive for the amount of attention allocated to T1. For both these purposes pupil dilation was measured, and analyzed with our recently developed deconvolution method. We found that the dynamics of temporal attention in small versus large blinkers differ in a number of ways. Individuals with a relatively small AB magnitude seem better able to preserve temporal order information. In addition, they are quicker to allocate attention to both T1 and T2 than large blinkers. Although a popular explanation of the AB is that it is caused by an unnecessary overinvestment of attention allocated to T1, a more complex picture emerged from our data, suggesting that this may depend on whether one is a small or a large blinker. The use of pupil dilation deconvolution seems to be a powerful approach to study the temporal dynamics of attention, bringing us a step closer to understanding the elusive nature of the AB. We conclude that the timing of attention to targets may be more important than the amount of allocated attention in accounting for individual differences.

  7. Safety assessment in plant layout design using indexing approach: Implementing inherent safety perspective

    International Nuclear Information System (INIS)

    Tugnoli, Alessandro; Khan, Faisal; Amyotte, Paul; Cozzani, Valerio

    2008-01-01

    Layout planning plays a key role in the inherent safety performance of process plants since this design feature controls the possibility of accidental chain-events and the magnitude of possible consequences. A lack of suitable methods to promote the effective implementation of inherent safety in layout design calls for the development of new techniques and methods. In the present paper, a safety assessment approach suitable for layout design in the critical early phase is proposed. The concept of inherent safety is implemented within this safety assessment; the approach is based on an integrated assessment of inherent safety guideword applicability within the constraints typically present in layout design. Application of these guidewords is evaluated along with unit hazards and control devices to quantitatively map the safety performance of different layout options. Moreover, the economic aspects related to safety and inherent safety are evaluated by the method. Specific sub-indices are developed within the integrated safety assessment system to analyze and quantify the hazard related to domino effects. The proposed approach is quick in application, auditable and shares a common framework applicable in other phases of the design lifecycle (e.g. process design). The present work is divided in two parts: Part 1 (current paper) presents the application of inherent safety guidelines in layout design and the index method for safety assessment; Part 2 (accompanying paper) describes the domino hazard sub-index and demonstrates the proposed approach with a case study, thus evidencing the introduction of inherent safety features in layout design

  8. Genetic affinity among five different population groups in India reflecting a Y-chromosome gene flow.

    Science.gov (United States)

    Saha, Anjana; Sharma, Swarkar; Bhat, Audesh; Pandit, Awadesh; Bamezai, Ramesh

    2005-01-01

    Four binary polymorphisms and four multiallelic short tandem repeat (STR) loci from the nonrecombining region of the human Y-chromosome were typed in different Indian population groups from Uttar Pradeh (UP), Bihar (BI), Punjab (PUNJ), and Bengal (WB) speaking the Indo-Aryan dialects and from South India (SI) with the root in the Dravidian language. We identified four major haplogroups [(P) 1+, (C and F) 2+, (R1a) 3, (K) 26+] and 114 combinations of Y-STR haplotypes. Analyses of the haplogroups indicated no single origin from any lineage but a result of a conglomeration of different lineages from time to time. The phylogenetic analyses indicate a high degree of population admixture and a greater genetic proximity for the studied population groups when compared with other world populations.

  9. Individual Differences in Temporal Selective Attention as Reflected in Pupil Dilation

    OpenAIRE

    Willems, Charlotte; Herdzin, Johannes; Martens, Sander

    2015-01-01

    Background Attention is restricted for the second of two targets when it is presented within 200-500 ms of the first target. This attentional blink (AB) phenomenon allows one to study the dynamics of temporal selective attention by varying the interval between the two targets (T1 and T2). Whereas the AB has long been considered as a robust and universal cognitive limitation, several studies have demonstrated that AB task performance greatly differs between individuals, with some individuals s...

  10. The becoming of an entrepreneurial opportunity.:– reflections on different ‘opportunity-ontologies’.

    OpenAIRE

    Herholdt-Lomholdt, Sine Maria

    2015-01-01

    As innovation and entrepreneurship is about bringing something “new” into the world, a key point must be focusing on the entrepreneurial opportunity and how we get access to entrepreneurial opportunities. Contemporary research within entrepreneurship and innovation are mainly based in different forms of constructivist and social-constructivist approaches, by Alvarez and Barney (Alvarez & Barney 2007; Alvarez & Barney 2010) named creation theory. Within these approaches the entrepreneu...

  11. Inherent optical properties of the coccolithophore: Emiliania huxleyi.

    Science.gov (United States)

    Zhai, Peng-Wang; Hu, Yongxiang; Trepte, Charles R; Winker, David M; Josset, Damien B; Lucker, Patricia L; Kattawar, George W

    2013-07-29

    A realistic nonspherical model for Emiliania huxleyi (EHUX) is built, based on electron micrographs of coccolithophore cells. The Inherent Optical Properties (IOP) of the EHUX are then calculated numerically by using the discrete dipole approximation. The coccolithophore model includes a near-spherical core with the refractive index of 1.04 + m(i)j, and a carbonate shell formed by smaller coccoliths with refractive index of 1.2 + m(i)j, where m(i) = 0 or 0.01 and j(2) = -1. The reported IOP are the Mueller scattering matrix, backscattering probability, and depolarization ratio. Our calculation shows that the Mueller matrices of coccolithophores show different angular dependence from those of coccoliths.

  12. Do Performance-based Health Measures Reflect Differences in Frailty Among Immigrants Age 50+ in Europe?

    Science.gov (United States)

    Brothers, Thomas D; Theou, Olga; Rockwood, Kenneth

    2014-09-01

    Life course influences, including country of residence and country of birth, are associated with frailty index scores. We investigated these associations using performance-based health measures. Among 33,745 participants age 50+ (mean age 64.8 ± 10.1; 55% women) in the Survey of Health, Ageing, and Retirement in Europe, grip strength, delayed word recall, and semantic verbal fluency were assessed. Participants were grouped by country of residence (Northern/Western Europe or Southern/Eastern Europe), and by country of birth (native-born, immigrants born in low- and middle-income countries [LMICs], or immigrants born in high-income countries [HICs]). Participants in Southern/Eastern Europe had lower mean test scores than those in Northern/Western Europe, and their scores did not differ by country of birth group. In Northern/Western Europe, compared with native-born participants, LMIC-born immigrants demonstrated lower mean grip strength (32.8 ± 7.6 kg vs. 35.7 ± 7.7 kg), delayed recall (2.9 ± 1.9 vs. 3.6 ± 1.9), and verbal fluency scores (16.0 ± 6.9 vs. 20.3 ± 7.0). HIC-born immigrants had mean scores higher than LMIC-born immigrants, but lower than native-born participants (all pnational income levels of both country of residence and country of birth. This was similar to previously observed differences in frailty index scores.

  13. [Do online ratings reflect structural differences in healthcare? The example of German physician-rating websites].

    Science.gov (United States)

    Meszmer, Nina; Jaegers, Lena; Schöffski, Oliver; Emmert, Martin

    2018-04-01

    Previous surveys have shown that patient satisfaction varies with the regional supply of physicians. Online ratings on physician-rating websites represent a relatively new instrument to display patient satisfaction results. The aim of this study was (1) to assess the current state of online ratings for two medical disciplines (dermatologists and ear, nose and throat (ENT) specialists), and (2) to analyze online derived patient satisfaction results according to the physician density in Germany. We collected online ratings for 420 dermatologists and 450 ear, nose, and throat (ENT) specialists on twelve German physician-rating websites. We analyzed the online ratings according to the physician density (low, medium, high physician density). For this purpose, we collected secondary data from both physician-rating websites and the regional associations of statutory health insurance physicians. Data analysis was performed using Median tests and Chi-square tests. In total, 10,239 online ratings for dermatologists and 8,168 online ratings for ENT specialists were analyzed. Almost all dermatologists (99.3 %) and ENT specialists (98.9 %) were listed on one of the physician-rating websites. A total of 93.5 % of all listed dermatologists and 96.9 % of ENT-specialists were rated on at least one of the physician-rating websites. Significant differences were found in the distribution (i.e., percentage of listed or rated physicians) of the ratings according to the regional physician density on only one physician-rating website (pexample, dermatologist ratings were better in regions with a higher physician density compared to regions with a lower number of physicians (average rating: 2.16 vs. 2.67; p<0.001). Online ratings of dermatologists and ENT specialists hardly differ in terms of regional physician density. Physician-rating websites thus do not appear to be appropriate to mirror differences in the health service delivery structure. Our findings thus do not confirm the

  14. CARABID BEATLES AS INDICATORS REFLECTING RIVERINE ENVIRONMENTAL CONDITIONS IN DIFFERENT TYPES OF RIVER REGULATIONS

    Directory of Open Access Journals (Sweden)

    Renata Kędzior

    2014-10-01

    Full Text Available The aim of the investigation was to estimate factors responsible for sustaining riverine communities in stream sections with various bank regulation systems. The research were conducted on Porebianka stream in the Polish Western Carpathians, where 10 different types of river regulations were chosen for the analysis (strong incision without alluvial deposits, redeposition with sand and gravel banks, concrete revetment walls along the banks, channel with banks lined with rip-rap and reference unmanaged cross- section. We conclude that the carabid beetles assemblages of the studied river sections respond mainly to hydraulic parameters of the stream. Elimination of frequent natural bank inundation (due to the regulations of the banks is the main factor responsible for the impoverishment and extinction of riverine communities.

  15. The cuticular hydrocarbons profiles in the stingless bee Melipona marginata reflect task-related differences.

    Science.gov (United States)

    Ferreira-Caliman, M J; Nascimento, F S; Turatti, I C; Mateus, S; Lopes, N P; Zucchi, R

    2010-07-01

    Members of social insect colonies employ a large variety of chemical signals during their life. Of these, cuticular hydrocarbons are of primary importance for social insects since they allow for the recognition of conspecifics, nestmates and even members of different castes. The objectives of this study were (1) to characterize the variation of the chemical profiles among workers of the stingless bee Melipona marginata, and (2) to investigate the dependence of the chemical profiles on the age and on the behavior of the studied individuals. The results showed that cuticular hydrocarbon profiles of workers were composed of alkanes, alkenes and alkadienes that varied quantitatively and qualitatively according to function of workers in the colony. Copyright 2010 Elsevier Ltd. All rights reserved.

  16. Cortical potentials in an auditory oddball task reflect individual differences in working memory capacity.

    Science.gov (United States)

    Yurgil, Kate A; Golob, Edward J

    2013-12-01

    This study determined whether auditory cortical responses associated with mechanisms of attention vary with individual differences in working memory capacity (WMC) and perceptual load. The operation span test defined subjects with low versus high WMC, who then discriminated target/nontarget tones while EEG was recorded. Infrequent white noise distracters were presented at midline or ±90° locations, and perceptual load was manipulated by varying nontarget frequency. Amplitude of the N100 to distracters was negatively correlated with WMC. Relative to targets, only high WMC subjects showed attenuated N100 amplitudes to nontargets. In the higher WMC group, increased perceptual load was associated with decreased P3a amplitudes to distracters and longer-lasting negative slow wave to nontargets. Results show that auditory cortical processing is associated with multiple facets of attention related to WMC and possibly higher-level cognition. Copyright © 2013 Society for Psychophysiological Research.

  17. Physical fitness of primary school children in the reflection of different levels of gross motor coordination

    Directory of Open Access Journals (Sweden)

    Ingrid Ružbarská

    2016-12-01

    Full Text Available Background: Lower level of motor competences may result in unsuccessful engaging of children in physical activities as early as pre-school age and also prepubescent ages. This may subsequently lead to a spiral of forming negative attitudes towards an active lifestyle and may be accompanied by a negative trend in weight status and physical fitness outcomes. Objective: The aim of the study was to identify and analyze differences in physical fitness and somatic parameters of primary school-aged children according to level of their gross motor coordination. Methods:  A sample of 436 children aged 7 to 10 years, of which were 222 girls and 214 boys, performed physical fitness tests - Eurofit test battery. The level of motor coordination was assessed using the test battery Körperkoordination-Test-für-Kinder (KTK. The anthropometric data (body mass, body height, sum of five skinfolds were measured. The one-way ANOVA was used to assess differences in physical fitness test items and anthropometry parameters between children with normal motor quotient (MQ ≥ 86 and decreased levels of gross motor coordination (MQ ≤ 85. Results: Research findings indicate a strongly negative trend in physical development of children with motor deficits (MQ ≤ 85. The results of ANOVA revealed significantly less favourable level of most of the assessed physical fitness parameters in children with decreased level of motor coordination. Conclusions: The findings suggest that physical fitness outcomes of primary school-aged children are associated with a lower level of motor coordination. Motor coordination probably plays an important role in preventing, or moderating the so-called negative trajectory leading to childhood overweight or obesity.

  18. A simple graphical method for measuring inherent safety

    International Nuclear Information System (INIS)

    Gupta, J.P.; Edwards, David W.

    2003-01-01

    addition of values for disparate hazards (temperature, pressure, inventory, toxicity, flammability, etc.) is being suggested to derive an overall ISD index value since that conceals the effects of different parameters. Further, addition of numbers with different units ( deg. C for temperature, atm/bar for pressure, t for inventory, etc.) is inappropriate in scientific sense. The proposed approach has a major advantage of expanding consideration in future to incorporate economic, regulatory, pollution control and worker health aspects, as well as factors such as the experience one has or 'the comfort level' one feels with each of the processes under consideration. Additionally, it would also guide the designers and decision makers into affecting specific changes in the processes to reduce the unsafe features. We demonstrate our simple approach by using the example of six routes to make methyl methacrylate as documented by Edwards and Lawrence [Trans. IChemE, Process Safety Environ. Protect. B 71 (4) (1993) 252; Quantifying inherent safety of chemical process routes, Ph.D. Thesis, Loughborough University, Loughborough, UK, 1996] and show that the decision could well have been different if addition of disparate hazards had not been done

  19. Molecular fingerprinting reflects different histotypes and brain region in low grade gliomas

    International Nuclear Information System (INIS)

    Mascelli, Samantha; Fasulo, Daniel; Noy, Karin; Wittemberg, Gayle; Pignatelli, Sara; Piatelli, Gianluca; Cama, Armando; Garré, Maria Luisa; Capra, Valeria; Verri, Alessandro; Barla, Annalisa; Raso, Alessandro; Mosci, Sofia; Nozza, Paolo; Biassoni, Roberto; Morana, Giovanni; Huber, Martin; Mircean, Cristian

    2013-01-01

    Paediatric low-grade gliomas (LGGs) encompass a heterogeneous set of tumours of different histologies, site of lesion, age and gender distribution, growth potential, morphological features, tendency to progression and clinical course. Among LGGs, Pilocytic astrocytomas (PAs) are the most common central nervous system (CNS) tumours in children. They are typically well-circumscribed, classified as grade I by the World Health Organization (WHO), but recurrence or progressive disease occurs in about 10-20% of cases. Despite radiological and neuropathological features deemed as classic are acknowledged, PA may present a bewildering variety of microscopic features. Indeed, tumours containing both neoplastic ganglion and astrocytic cells occur at a lower frequency. Gene expression profiling on 40 primary LGGs including PAs and mixed glial-neuronal tumours comprising gangliogliomas (GG) and desmoplastic infantile gangliogliomas (DIG) using Affymetrix array platform was performed. A biologically validated machine learning workflow for the identification of microarray-based gene signatures was devised. The method is based on a sparsity inducing regularization algorithm l 1 l 2 that selects relevant variables and takes into account their correlation. The most significant genetic signatures emerging from gene-chip analysis were confirmed and validated by qPCR. We identified an expression signature composed by a biologically validated list of 15 genes, able to distinguish infratentorial from supratentorial LGGs. In addition, a specific molecular fingerprinting distinguishes the supratentorial PAs from those originating in the posterior fossa. Lastly, within supratentorial tumours, we also identified a gene expression pattern composed by neurogenesis, cell motility and cell growth genes which dichotomize mixed glial-neuronal tumours versus PAs. Our results reinforce previous observations about aberrant activation of the mitogen-activated protein kinase (MAPK) pathway in LGGs

  20. Does the age-related positivity effect in autobiographical recall reflect differences in appraisal or memory?

    Science.gov (United States)

    Schryer, Emily; Ross, Michael

    2014-07-01

    Two studies examined the extent to which the age-related positivity effect in autobiographical recall is the result of age differences in appraisal and memory. In Study 1, older and younger participants reported 1 pleasant and 1 unpleasant event for 5 days. Participants attempted to recall those events a week later. In Study 2, older and younger participants imagined that positive, negative, and neutral hypothetical events had occurred either to themselves or to an acquaintance and were later asked to recall those events. In Study 1, younger adults reported a complete set of positive and negative events. Older adults reported a pleasant event each day, but 38% did not report an unpleasant event on at least 1 day. A week later, older and younger adults were equally likely to recall the events they had reported. In Study 2, older adults who imagined events happened to themselves rated events as more positive in valence than younger adults did. Older and younger adults were equally likely to remember pleasant and unpleasant events at the end of the study. The data suggest that the age-related positivity effect resides in the appraisal rather than the recall of autobiographical events. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  1. Different Endosymbiotic Interactions in Two Hydra Species Reflect the Evolutionary History of Endosymbiosis

    KAUST Repository

    Ishikawa, Masakazu; Yuyama, Ikuko; Shimizu, Hiroshi; Nozawa, Masafumi; Ikeo, Kazuho; Gojobori, Takashi

    2016-01-01

    Endosymbiosis is an important evolutionary event for organisms, and there is widespread interest in understanding the evolution of endosymbiosis establishment. Hydra is one of the most suitable organisms for studying the evolution of endosymbiosis. Within the genus Hydra, H. viridissima and H. vulgaris show endosymbiosis with green algae. Previous studies suggested that the endosymbiosis in H. vulgaris took place much more recently than that in H. viridissima, noting that the establishment of the interaction between H. vulgaris and its algae is not as stable as in H. viridissima. To investigate the on-going process of endosymbiosis, we first compared growth and tolerance to starvation in symbiotic and aposymbiotic polyps of both species. The results revealed that symbiotic H. viridissima had a higher growth rate and greater tolerance to starvation than aposymbiotic polyps. By contrast, growth of symbiotic H. vulgaris was identical to that of aposymbiotic polyps, and symbiotic H. vulgaris was less tolerant to starvation. Moreover, our gene expression analysis showed a pattern of differential gene expression in H. viridissima similar to that in other endosymbiotically established organisms, and contrary to that observed in H. vulgaris. We also showed that H. viridissima could cope with oxidative stress that caused damage, such as cell death, in H. vulgaris. These observations support the idea that oxidative stress related genes play an important role in the on-going process of endosymbiosis evolution. The different evolutionary stages of endosymbiosis studied here provide a deeper insight into the evolutionary processes occurring toward a stable endosymbiosis.

  2. Sunk cost and work ethic effects reflect suboptimal choice between different work requirements.

    Science.gov (United States)

    Magalhães, Paula; White, K Geoffrey

    2013-03-01

    We investigated suboptimal choice between different work requirements in pigeons (Columba livia), namely the sunk cost effect, an irrational tendency to persist with an initial investment, despite the availability of a better option. Pigeons chose between two keys, one with a fixed work requirement to food of 20 pecks (left key), and the other with a work requirement to food which varied across conditions (center key). On some trials within each session, such choices were preceded by an investment of 35 pecks on the center key, whereas on others they were not. On choice trials preceded by the investment, the pigeons tended to stay and complete the schedule associated with the center key, even when the number of pecks to obtain reward was greater than for the concurrently available left key. This result indicates that pigeons, like humans, commit the sunk cost effect. With higher work requirements, this preference was extended to trials where there was no initial investment, so an overall preference for the key associated with more work was evident, consistent with the work ethic effect. We conclude that a more general work ethic effect is amplified by the effect of the prior investment, that is, the sunk cost effect. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. Different Endosymbiotic Interactions in Two Hydra Species Reflect the Evolutionary History of Endosymbiosis

    KAUST Repository

    Ishikawa, Masakazu

    2016-06-19

    Endosymbiosis is an important evolutionary event for organisms, and there is widespread interest in understanding the evolution of endosymbiosis establishment. Hydra is one of the most suitable organisms for studying the evolution of endosymbiosis. Within the genus Hydra, H. viridissima and H. vulgaris show endosymbiosis with green algae. Previous studies suggested that the endosymbiosis in H. vulgaris took place much more recently than that in H. viridissima, noting that the establishment of the interaction between H. vulgaris and its algae is not as stable as in H. viridissima. To investigate the on-going process of endosymbiosis, we first compared growth and tolerance to starvation in symbiotic and aposymbiotic polyps of both species. The results revealed that symbiotic H. viridissima had a higher growth rate and greater tolerance to starvation than aposymbiotic polyps. By contrast, growth of symbiotic H. vulgaris was identical to that of aposymbiotic polyps, and symbiotic H. vulgaris was less tolerant to starvation. Moreover, our gene expression analysis showed a pattern of differential gene expression in H. viridissima similar to that in other endosymbiotically established organisms, and contrary to that observed in H. vulgaris. We also showed that H. viridissima could cope with oxidative stress that caused damage, such as cell death, in H. vulgaris. These observations support the idea that oxidative stress related genes play an important role in the on-going process of endosymbiosis evolution. The different evolutionary stages of endosymbiosis studied here provide a deeper insight into the evolutionary processes occurring toward a stable endosymbiosis.

  4. Modeling Bidirectional Reflectance Distribution Function of One-dimensional Random Rough Surfaces with the Finite Difference Time Domain Method

    Directory of Open Access Journals (Sweden)

    Min-Jhong Gu

    2014-08-01

    Full Text Available This article describes the development of a suite of programs that is capable of simulating the radiation properties of a random rough surface (RRS. The fundamental approach involves the generation, by fast Fourier transform (FFT built with rigorous finite difference time domain (FDTD, as the theoretical basis for the simulation of a bidirectional reflectance distribution function (BRDF of the RRS. The results are compared with the measurements and modeling of existing work to verify the feasibility of customized programming. It was found that the results of this study were a better match to the measurement data than those achieved in other modeling work.

  5. Does the inherence heuristic take us to psychological essentialism?

    Science.gov (United States)

    Marmodoro, Anna; Murphy, Robin A; Baker, A G

    2014-10-01

    We argue that the claim that essence-based causal explanations emerge, hydra-like, from an inherence heuristic is incomplete. No plausible mechanism for the transition from concrete properties, or cues, to essences is provided. Moreover, the fundamental shotgun and storytelling mechanisms of the inherence heuristic are not clearly enough specified to distinguish them, developmentally, from associative or causal networks.

  6. Different Phases of Earthquake Cycle Reflected in GPS Measured Crustal Deformations along the Andes

    Science.gov (United States)

    Khazaradze, G.; Klotz, J.

    2001-12-01

    largest ever recorded earthquake on the earth. To properly interpret given observations, we developed the fully \\textsc{3D} Andean Elastic Dislocation Model (AEDM), which is used to explain the dominant inter-seismic signal. The subtraction of the AEDM predicted deformation rates from the observations leads towards the "filtered" residual velocity field, that can be used to highlight, for example, the post-seismic deformation effects. Also, in the central section of the SAGA network, the residual velocity field indicates the existence of more long-term (i.e. geologic) deformations. In summary, the changing spatial-temporal pattern of GPS measured crustal deformation rates along the central and southern Andes is governed by the relative importance of different phases of earthquake deformation cycle.

  7. Food plant toxicants and safety - Risk assessment and regulation of inherent toxicants in plant foods

    DEFF Research Database (Denmark)

    Essers, A.J.A.; Alink, G.M.; Speijers, G.J.A.

    1998-01-01

    The ADI as a tool for risk management and regulation of food additives and pesticide residues is not readily applicable to inherent food plant toxicants: The margin between actual intake and potentially toxic levels is often small; application of the default uncertainty factors used to derive ADI...... values, particularly when extrapolating from animal data, would prohibit the utilisation of the food, which may have an overall beneficial health effect. Levels of inherent toxicants are difficult to control; their complete removal is not always wanted, due to their function for the plant or for human...... health. The health impact of the inherent toxicant is often modified by factors in the food, e.g. the bioavailability from the matrix and interaction with other inherent constituents. Risk-benefit analysis should be made for different consumption scenarios, without the use of uncertainty factors. Crucial...

  8. Approaches to achieving inherently safe fusion power plants

    International Nuclear Information System (INIS)

    Piet, S.J.

    1986-01-01

    Achieving inherently safe fusion facilities and conceptual designs is a challenge to the fusion community. Success should provide fusion with important competitive advantages versus other energy technologies. Inherent safety should mean a facility designed with passive safety features such that the public is protected from any acute fatalities under all credible accidental circumstances. A key aspect to inherent safety is demonstrability - the ability to prove that a deign is as safe as claimed. Three complementary approaches to achieving inherent safety are examined: toxin inventory reduction, energy source reduction and design fault tolerance. Four levels of assurance are defined, associated with uncertainty in the words ''credible' and ''demonstrable.'' Sound reasons exist for believing that inherent safety puts a modest upper bound on all accident consequences; it should be considered a part of the collection of safety and environmental issues, which also include lower consequence accidents, waste management, and effluent control

  9. Development of physiotherapy inherent requirement statements - an Australian experience.

    Science.gov (United States)

    Bialocerkowski, Andrea; Johnson, Amanda; Allan, Trevor; Phillips, Kirrilee

    2013-04-16

    The United Nations Convention on the Rights of People with Disabilities promotes equal rights of people with a disability in all aspects of their life including their education. In Australia, Disability Discrimination legislation underpins this Convention. It mandates that higher education providers must demonstrate that no discrimination has occurred and all reasonable accommodations have been considered and implemented, to facilitate access and inclusion for a student with a disability. The first step to meeting legislative requirements is to provide students with information on the inherent requirements of a course. This paper describes the steps which were taken to develop inherent requirement statements for a 4-year entry-level physiotherapy program at one Australian university. Inherent requirement statements were developed using an existing framework, which was endorsed and mandated by the University. Items which described inherencies were extracted from Australian physiotherapy professional standards and statutory regulatory requirements, and units contained in the physiotherapy program. Data were integrated into the 8 prescribed domains: ethical behaviour, behavioural stability, legal, communication, cognition, sensory abilities, strength and mobility, and sustainable performance. Statements for each domain were developed using a 5-level framework (introductory statement, description of the inherent requirement, justification for inherency, characteristics of reasonable adjustments and exemplars) and reviewed by a University Review Panel. Refinement of statements continued until no further changes were required. Fifteen physiotherapy inherent requirement statements were developed. The eight domains identified in the existing framework, developed for Nursing, were relevant to the study of physiotherapy. The inherent requirement statements developed in this study provide a transparent, defensible position on the current requirements of physiotherapy study at

  10. Development of physiotherapy inherent requirement statements – an Australian experience

    Science.gov (United States)

    2013-01-01

    Background The United Nations Convention on the Rights of People with Disabilities promotes equal rights of people with a disability in all aspects of their life including their education. In Australia, Disability Discrimination legislation underpins this Convention. It mandates that higher education providers must demonstrate that no discrimination has occurred and all reasonable accommodations have been considered and implemented, to facilitate access and inclusion for a student with a disability. The first step to meeting legislative requirements is to provide students with information on the inherent requirements of a course. This paper describes the steps which were taken to develop inherent requirement statements for a 4-year entry-level physiotherapy program at one Australian university. Case presentation Inherent requirement statements were developed using an existing framework, which was endorsed and mandated by the University. Items which described inherencies were extracted from Australian physiotherapy professional standards and statutory regulatory requirements, and units contained in the physiotherapy program. Data were integrated into the 8 prescribed domains: ethical behaviour, behavioural stability, legal, communication, cognition, sensory abilities, strength and mobility, and sustainable performance. Statements for each domain were developed using a 5-level framework (introductory statement, description of the inherent requirement, justification for inherency, characteristics of reasonable adjustments and exemplars) and reviewed by a University Review Panel. Refinement of statements continued until no further changes were required. Fifteen physiotherapy inherent requirement statements were developed. The eight domains identified in the existing framework, developed for Nursing, were relevant to the study of physiotherapy. Conclusions The inherent requirement statements developed in this study provide a transparent, defensible position on the

  11. Adult age-differences in subjective impression of emotional faces are reflected in emotion-related attention and memory tasks

    Directory of Open Access Journals (Sweden)

    Joakim eSvard

    2014-05-01

    Full Text Available Although younger and older adults appear to attend to and remember emotional faces differently, less is known about age-related differences in the subjective emotional impression (arousal, potency, and valence of emotional faces and how these differences, in turn, are reflected in age differences in various emotional tasks. In the current study, we used the same facial emotional stimuli (angry and happy faces in four tasks: emotional rating, attention, categorical perception, and visual short-term memory (VSTM. The aim of this study was to investigate effects of age on the subjective emotional impression of angry and happy faces and to examine whether any age differences were mirrored in measures of emotional behavior (attention, categorical perception, and memory.In addition, regression analyses were used to further study impression-behavior associations. Forty younger adults (range 20-30 years and thirty-nine older adults (range 65-75 years participated in the experiment. The emotional rating task showed that older adults perceived less arousal, potency, and valence than younger adults and that the difference was more pronounced for angry than happy faces. Similarly, the results of the attention and memory tasks demonstrated interaction effects between emotion and age, and age differences on these measures were larger for angry than for happy faces. Regression analyses confirmed that in both age groups, higher potency ratings predicted both visual search and visual short-term memory efficiency. Future studies should consider the possibility that age differences in the subjective emotional impression of facial emotional stimuli may explain age differences in attention to and memory of such stimuli.

  12. Communicating uncertainty: managing the inherent probabilistic character of hazard estimates

    Science.gov (United States)

    Albarello, Dario

    2013-04-01

    Science is much more fixing the limits of our knowledge about possible occurrences than the identification of any "truth". This is particularly true when scientific statements concern prediction of natural phenomena largely exceeding the laboratory scale as in the case of seismogenesis. In these cases, many scenarios about future occurrences result possible (plausible) and the contribution of scientific knowledge (based on the available knowledge about underlying processes or the phenomenological studies) mainly consists in attributing to each scenario a different level of likelihood (probability). In other terms, scientific predictions in the field of geosciences (hazard assessment) are inherently probabilistic. However, despite of this, many scientist (seismologists, etc.) in communicating their position in public debates tend to stress the " truth" of their statements against the fancy character of pseudo-scientific assertions: stronger is the opposition of science and pseudo-science, more hidden becomes the probabilistic character of scientific statements. The problem arises when this kind of "probabilistic" knowledge becomes the basis of any political action (e.g., to impose expensive form of risk reducing activities): in these cases the lack of any definitive "truth" requires a direct assumption of responsibility by the relevant decider (being the single citizen or the legitimate expression of a larger community) to choose among several possibilities (however characterized by different levels of likelihood). In many cases, this can be uncomfortable and strong is the attitude to delegate to the scientific counterpart the responsibility of these decisions. This "transfer" from the genuine political field to an improper scientific context is also facilitated by the lack of a diffuse culture of "probability" outside the scientific community (and in many cases inside also). This is partially the effect of the generalized adoption (by media and scientific

  13. Inherent Anticipation in the Pharmaceutical and Biotechnology Industries.

    Science.gov (United States)

    Goldman, Michael; Evans, Georgia; Zappia, Andrew

    2015-04-15

    Pharmaceutical and biotech research often involves discovering new properties of, or new methods to use, existing compositions. The doctrine of inherent anticipation, however, prevents the issuance and/or validity of a patent for discoveries deemed to have been implicitly disclosed in the prior art. This can be a barrier to patent rights in these technologies. Inherent anticipation therefore creates uncertainty for patent protection in the pharmaceutical and biotech sciences. Despite this uncertainty, Federal Circuit jurisprudence provides guidance on the boundaries of the inherent anticipation doctrine. In view of the case law, certain strategies may be employed to protect inventions that may potentially be viewed as inherent in the prior art. Copyright © 2015 Cold Spring Harbor Laboratory Press; all rights reserved.

  14. Worldwide distribution of Total Reflection X-ray Fluorescence instrumentation and its different fields of application: A survey

    Energy Technology Data Exchange (ETDEWEB)

    Klockenkämper, Reinhold, E-mail: reinhold.klockenkaemper@isas.de; Bohlen, Alex von

    2014-09-01

    A survey was carried out with users and manufacturers of Total Reflection X-ray Fluorescence instrumentation in order to demonstrate the worldwide distribution of TXRF equipment and the different fields of applications. In general, TXRF users come from universities and scientific institutes, from working places at synchrotron beam-lines, or laboratories in semiconductor fabs. TXRF instrumentation is distributed in more than 50 countries on six continents and is applied at about 200 institutes and laboratories. The number of running desktop instruments amounts to nearly 300 units. About 60 beamlines run working places dedicated to TXRF. About 300 floor-mounted instruments are estimated to be used in about 150 fabs of the semiconductor industry. In total, 13 different fields of applications could be registered statistically from three different aspects. - Highlights: • According to the survey world maps show the distribution of TXRF equipment. • Nearly 700 individual units are running actually in 57 countries of 6 continents. • Users work at 200 universities, 60 synchrotron-beamlines, and 150 semiconductor fabs. • 13 fields of applications (e.g. environmental, chemical) are evaluated statistically. • Manufacturers, conference members and authors lead to 3 different pie-charts.

  15. Standard test method for measurement of light reflectance value and small color differences between pieces of ceramic tile

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2007-01-01

    1.1 This test method covers the measurement of Light Reflectance Value (LRV) and visually small color difference between pieces of glazed or unglazed ceramic tile, using any spectrophotometer that meets the requirements specified in the test method. LRV and the magnitude and direction of the color difference are expressed numerically, with sufficient accuracy for use in product specification. 1.2 LRV may be measured for either solid-colored tile or tile having a multicolored, speckled, or textured surface. For tile that are not solid-colored, an average reading should be obtained from multiple measurements taken in a pattern representative of the overall sample as described in 9.2 of this test method. Small color difference between tiles should only be measured for solid-color tiles. Small color difference between tile that have a multicolored, speckled, or textured surface, are not valid. 1.3 For solid colored tile, a comparison of the test specimen and reference specimen should be made under incandescent, f...

  16. Reflecting reflection in supervision

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang

    associated with reflection and an exploration of alternative conceptions that view reflection within the context of settings which have a more group- and team-based orientation. Drawing on an action research project on health care supervision, the paper questions whether we should reject earlier views...... of reflection, rehabilitate them in order to capture broader connotations or move to new ways of regarding reflection that are more in keeping with not only reflective but also emotive, normative and formative views on supervision. The paper presents a critical perspective on supervision that challenge...... the current reflective paradigm I supervision and relate this to emotive, normative and formative views supervision. The paper is relevant for Nordic educational research into the supervision and guidance...

  17. Do differences in visuospatial ability between senile dementias of the Alzheimer and Lewy body types reflect differences solely in mnemonic function?

    Science.gov (United States)

    Sahgal, A; McKeith, I G; Galloway, P H; Tasker, N; Steckler, T

    1995-02-01

    Visuospatial memory was investigated in two groups of patients suffering from senile dementias of the Alzheimer (SDAT) or Lewy body (SDLT) types; a, third, age-matched, healthy control group was also included. The two patient groups were mildly demented and could not be distinguished from each other by traditional tests of cognitive function. A different pattern of performance emerged in the two groups on a computerised test of spatial working memory, which is a self-ordered pointing task requiring the subject to search for hidden tokens. An analysis of the pattern of errors revealed that the SDLT group made more of both possible types of error ("Within Search" and "Between Search") than the SDAT group. Neither patient groups' performance differed from each other when assessed on a computerised Corsi spatial span task. A measure of planning ability was obtained by examining search strategies. Although an index previously developed to measure the subject's use of a particular strategy in the spatial working memory task failed to detect any differences between the three groups, a novel index was calculated which focuses on performance within a search, and this revealed deficits in both demented groups. Since the two patient groups differed from each other in the spatial working memory, but not the Corsi spatial span, task, it is suggested that the differences between the two demented groups are not due to a specific mnemonic impairment, but reflect dysfunctions in non-mnemonic processes mediated by fronto-subcortical circuits, which are more severely damaged in SDLT.

  18. Gene network inherent in genomic big data improves the accuracy of prognostic prediction for cancer patients.

    Science.gov (United States)

    Kim, Yun Hak; Jeong, Dae Cheon; Pak, Kyoungjune; Goh, Tae Sik; Lee, Chi-Seung; Han, Myoung-Eun; Kim, Ji-Young; Liangwen, Liu; Kim, Chi Dae; Jang, Jeon Yeob; Cha, Wonjae; Oh, Sae-Ock

    2017-09-29

    Accurate prediction of prognosis is critical for therapeutic decisions regarding cancer patients. Many previously developed prognostic scoring systems have limitations in reflecting recent progress in the field of cancer biology such as microarray, next-generation sequencing, and signaling pathways. To develop a new prognostic scoring system for cancer patients, we used mRNA expression and clinical data in various independent breast cancer cohorts (n=1214) from the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) and Gene Expression Omnibus (GEO). A new prognostic score that reflects gene network inherent in genomic big data was calculated using Network-Regularized high-dimensional Cox-regression (Net-score). We compared its discriminatory power with those of two previously used statistical methods: stepwise variable selection via univariate Cox regression (Uni-score) and Cox regression via Elastic net (Enet-score). The Net scoring system showed better discriminatory power in prediction of disease-specific survival (DSS) than other statistical methods (p=0 in METABRIC training cohort, p=0.000331, 4.58e-06 in two METABRIC validation cohorts) when accuracy was examined by log-rank test. Notably, comparison of C-index and AUC values in receiver operating characteristic analysis at 5 years showed fewer differences between training and validation cohorts with the Net scoring system than other statistical methods, suggesting minimal overfitting. The Net-based scoring system also successfully predicted prognosis in various independent GEO cohorts with high discriminatory power. In conclusion, the Net-based scoring system showed better discriminative power than previous statistical methods in prognostic prediction for breast cancer patients. This new system will mark a new era in prognosis prediction for cancer patients.

  19. Inherent variation in multiple shoe-sole test impressions.

    Science.gov (United States)

    Shor, Yaron; Wiesner, Sarena; Tsach, Tsadok; Gurel, Ron; Yekutieli, Yoram

    2018-04-01

    Shoeprints left at crime scenes are seldom perfect. Many prints are distorted or contaminated by various materials. Noisy background often contributes to vagueness on the shoeprints as well. Test impressions made from the suspect's shoes in the laboratory are considered a genuine replication of the shoe-sole. This naïve attitude is far from being correct. Consecutive test impressions made in the laboratory under strict similar conditions revealed differences among the exemplars of the same sole. Some of them are minor, but some are major, and can mislead the less experienced practitioners during the comparison process. This article focuses on the inherent within source variability between controlled shoeprints made from the same shoe, as it appears on the RACs. To describe and analyze this variability, repeated test impressions were prepared, and datasets were created. Several RACs were marked on each test impression, using an expert assisting software tool (developed in the authors' lab). The variance in repeated test impressions is demonstrated and possible sources are discussed. This variance should be considered when trying to establish the degree of matching between individual characteristics. Copyright © 2017. Published by Elsevier B.V.

  20. Managing inherent complexity for sustainable walleye fisheries in Lake Erie

    Science.gov (United States)

    Roseman, Edward F.; Drouin, Richard; Gaden, Marc; Knight, Roger; Tyson, Jeff; Zhao, Yingming; Taylor, William W.; Lynch, Abigail J.; Léonard, Nancy J.

    2012-01-01

    In Lake Erie, Walleye (Sander vitreus vitreus) is king. The naturally occurring species is the foundation of commercial fishing operations on the Canadian side of the lake and is a much-prized sport fish on the American side. Management of Lake Erie walleye fisheries is complex and takes place in an inter-jurisdictional setting composed of resource agencies from the states of Michigan (MDNR), Ohio (ODNR), Pennsylvania (PFBC), and New York (NYDEC) and the province of Ontario (OMNR). The complexity of walleye management is exacerbated by interactions among environmental and ecological changes in Lake Erie, complex life-history characteristics of the species, public demand for walleye, and cultural/governance differences among managing groups and their respective constituents. Success of future management strategies will largely hinge upon our ability to understand these inherent complexities and to employ tactics that successfully accommodate stock productivity and human demand in a highly dynamic environment. In this report, we review the history of Lake Erie walleye management, outline the multi-jurisdictional process for international management of walleye, and discuss strategies to address challenges facing managers.

  1. Stress measurements by multi-reflection grazing-incidence X-ray diffraction method (MGIXD) using different radiation wavelengths and different incident angles

    International Nuclear Information System (INIS)

    Marciszko, Marianna; Baczmański, Andrzej; Braham, Chedly; Wróbel, Mirosław; Wroński, Sebastian; Cios, Grzegorz

    2017-01-01

    The presented study introduces the development of the multi-reflection grazing-incidence X-ray diffraction method (MGIXD) for residual stress determination. The proposed new methodology is aimed at obtaining more reliable experimental data and increasing the depth of non-destructive stress determination below the sample surface. To verify proposed method measurements were performed on a classical X-ray diffractometer (Cu Kα radiation) and using synchrotron radiation (three different wavelengths: λ = 1.2527 Å, λ = 1.5419 Å and λ = 1.7512 Å). The Al2017 alloy subjected to three different surface treatments was investigated in this study. The obtained results showed that the proposed development of MGIXD method, in which not only different incident angles but also different wavelengths of X-ray are used, can be successfully applied for residual stress determination, especially when stress gradients are present in the sample.

  2. Classification and Discrimination of Different Fungal Diseases of Three Infection Levels on Peaches Using Hyperspectral Reflectance Imaging Analysis

    Directory of Open Access Journals (Sweden)

    Ye Sun

    2018-04-01

    Full Text Available Peaches are susceptible to infection from several postharvest diseases. In order to control disease and avoid potential health risks, it is important to identify suitable treatments for each disease type. In this study, the spectral and imaging information from hyperspectral reflectance (400~1000 nm was used to evaluate and classify three kinds of common peach disease. To reduce the large dimensionality of the hyperspectral imaging, principal component analysis (PCA was applied to analyse each wavelength image as a whole, and the first principal component was selected to extract the imaging features. A total of 54 parameters were extracted as imaging features for one sample. Three decayed stages (slight, moderate and severe decayed peaches were considered for classification by deep belief network (DBN and partial least squares discriminant analysis (PLSDA in this study. The results showed that the DBN model has better classification results than the classification accuracy of the PLSDA model. The DBN model based on integrated information (494 features showed the highest classification results for the three diseases, with accuracies of 82.5%, 92.5%, and 100% for slightly-decayed, moderately-decayed and severely-decayed samples, respectively. The successive projections algorithm (SPA was used to select the optimal features from the integrated information; then, six optimal features were selected from a total of 494 features to establish the simple model. The SPA-PLSDA model showed better results which were more feasible for industrial application. The results showed that the hyperspectral reflectance imaging technique is feasible for detecting different kinds of diseased peaches, especially at the moderately- and severely-decayed levels.

  3. Academic Excellence: A Commentary and Reflections on the Inherent Value of Peer Review

    Science.gov (United States)

    Roberts, Thomas J.; Shambrook, Jennifer

    2012-01-01

    Academic peer review is widely viewed as fair, equitable, and essential to academic quality. Successfully completing the process through publication or award is widely deemed as one of the most rigorous and prestigious forms of scholarly accomplishment. Despite this sentiment the academic peer review process is not without fault. It is criticized…

  4. Inherent work suit buoyancy distribution: effects on lifejacket self-righting performance.

    Science.gov (United States)

    Barwood, Martin J; Long, Geoffrey M; Lunt, Heather; Tipton, Michael J

    2014-09-01

    Accidental immersion in cold water is an occupational risk. Work suits and life jackets (LJ) should work effectively in combination to keep the airway clear of the water (freeboard) and enable self-righting. We hypothesized that inherent buoyancy, in the suit or LJ, would be beneficial for enabling freeboard, but its distribution may influence LJ self-righting. Six participants consented to complete nine immersions. Suits and LJ tested were: flotation suit (FLOAT; 85 N inherent buoyancy); oilskins 1 (OS-1) and 2 (OS-2), both with no inherent buoyancy; LJs (inherent buoyancy/buoyancy after inflation/total buoyancy), LJ-1 50/150/200 N, LJ-2 0/290/290 N, LJ-3 80/190/270 N. Once dressed, the subject entered an immersion pool where uninflated freeboard, self-righting performance, and inflated freeboard were measured. Data were compared using Friedman's test to the 0.05 alpha level. All suits and LJs enabled uninflated and inflated freeboard, but differences were seen between the suits and LJs. Self-righting was achieved on 43 of 54 occasions, irrespective of suit or LJ. On all occasions that self-righting was not achieved, this occurred in an LJ that included inherent buoyancy (11/54 occasions). Of these 11 failures, 8 occurred (73% of occasions) when the FLOAT suit was being worn. LJs that included inherent buoyancy, that are certified as effective on their own, worked less effectively from the perspective of self-righting in combination with a work suit that also included inherent buoyancy. Equipment that is approved for use in the workplace should be tested in combination to ensure adequate performance in an emergency scenario.

  5. Preliminary Studies on the Reflectance Characteristics of graphene/SiO2 under Different Applied Voltages for Optical Modulation Applications

    Science.gov (United States)

    Beh, K. P.; Yam, F. K.; Abdalrheem, Raed; Ng, Y. Z.; Suhaimi, F. H. A.; Lim, H. S.; Mat Jafri, M. Z.

    2018-04-01

    A preliminary study on the interband transition of graphene was done via reflectance spectra of graphene/SiO2 sample at various applied potential. Prior to that, Raman spectroscopy and four-point probe measurement was done on graphene/SiO2 sample. It was found that the sample consisted of monolayer graphene with sheet resistance around 402.32 Ω/□. Post-processing of the reflectance data lead to the plot of ratio of change in reflectance towards reflectance at 0 V (ΔR/R) against applied potential. From there, the ratio increases along with applied potential, indicative of higher absorption due to interband transition.

  6. Large Eddy Simulation for an inherent boron dilution transient

    International Nuclear Information System (INIS)

    Jayaraju, S.T.; Sathiah, P.; Komen, E.M.J.; Baglietto, E.

    2013-01-01

    Highlights: • Large Eddy Simulation is performed for a transient boron dilution scenario in the scaled experimental facility of ROCOM. • Fully conformal polyhedral grid of 14 million is created to capture all details of the domain. • Systematic multi-step validation methodology is followed to assess the accuracy of LES model. • For the presently simulated BDT scenario, the LES results lend support to its reliability in consistently predicting the slug transport in the RPV. -- Abstract: The present paper focuses on the validation and applicability of large eddy simulation (LES) to analyze the transport and mixing in the reactor pressure vessel (RPV) during an inherent boron dilution transient (BDT) scenario. Extensive validation data comes from relevant integral tests performed in the scaled ROCOM experimental facility. The modeling of sub-grid-scales is based on the WALE model. A fully conformal polyhedral grid of about 15 million cells is constructed to capture all details in the domain, including the complex structures of the lower-plenum. Detailed qualitative and quantitative validations are performed by following a systematic multi-step validation methodology. Qualitative comparisons to the experimental data in the cold legs, downcomer and the core inlet showed good predictions by the LES model. Minor deviations seen in the quantitative comparisons are rigorously quantified. A key parameter which is affecting the core neutron kinetics response is the value of highest deborated slug concentration that occurs at the core inlet during the transient. Detailed analyses are made at the core inlet to evaluate not only the value of the maximum slug concentration, but also the location and the time at which it occurs during the transient. The relative differences between the ensemble averaged experimental data and CFD predictions were within the range of relative differences seen within 10 different experimental realizations. For the studied scenario, the

  7. Inherent-opening-controlled pattern formation in carbon nanotube arrays

    International Nuclear Information System (INIS)

    Huang Xiao; Zhou, Jijie J; Sansom, Elijah; Gharib, Morteza; Haur, Sow Chorng

    2007-01-01

    We have introduced inherent openings into densely packed carbon nanotube arrays to study self-organized pattern formation when the arrays undergo a wetting-dewetting treatment from nanotube tips. These inherent openings, made of circular or elongated hollows in nanotube mats, serve as dewetting centres, from where liquid recedes from. As the dewetting centres initiate dry zones and the dry zones expand, surrounding nanotubes are pulled away from the dewetting centres by liquid surface tension. Among short nanotubes, the self-organized patterns are consistent with the shape of the inherent openings, i.e. slender openings lead to elongated trench-like structures, and circular holes result in relatively round nest-like arrangements. Nanotubes in a relatively high mat are more connected, like in an elastic body, than those in a short mat. Small cracks often initialize themselves in a relatively high mat, along two or more adjacent round openings; each of the cracks evolves into a trench as liquid dries up. Self-organized pattern control with inherent openings needs to initiate the dewetting process above the nanotube tips. If there is no liquid on top, inherent openings barely enlarge themselves after the wetting-dewetting treatment

  8. Memory accessibility shapes explanation: Testing key claims of the inherence heuristic account.

    Science.gov (United States)

    Hussak, Larisa J; Cimpian, Andrei

    2018-01-01

    People understand the world by constructing explanations for what they observe. It is thus important to identify the cognitive processes underlying these judgments. According to a recent proposal, everyday explanations are often constructed heuristically: Because people need to generate explanations on a moment-by-moment basis, they cannot perform an exhaustive search through the space of possible reasons, but may instead use the information that is most easily accessible in memory (Cimpian & Salomon 2014a, b). In the present research, we tested two key claims of this proposal that have so far not been investigated. First, we tested whether-as previously hypothesized-the information about an entity that is most accessible in memory tends to consist of inherent or intrinsic facts about that entity, rather than extrinsic (contextual, historical, etc.) facts about it (Studies 1 and 2). Second, we tested the implications of this difference in the memory accessibility of inherent versus extrinsic facts for the process of generating explanations: Does the fact that inherent facts are more accessible than relevant extrinsic facts give rise to an inherence bias in the content of the explanations generated (Studies 3 and 4)? The findings supported the proposal that everyday explanations are generated in part via a heuristic process that relies on easily accessible-and often inherent-information from memory.

  9. Cost-competitive, inherently safe LFMBR pool plant

    International Nuclear Information System (INIS)

    McDonald, J.S.; Brunings, J.E.; Chang, Y.I.; Hren, R.R.; Seidensticker, R.W.

    1984-01-01

    The Cost-Competitive, Inherently Safe LMFBR Pool Plant design was prepared in GFY 1983 under a DOE-sponsored program. This plant design was developed as a joint effort by Rockwell International and the Argonne National Laboratory with major contributions from the Bechtel Group, Inc.; Combustion engineering, Inc.; the Chicago Bridge and Iron Company; and the General Electric Company. Using current LMFBR technology, many innovative features were developed and incorporated into the design to meet the ultimate objectives of the Breeder Program, i.e., energy costs competitive with LWRs and inherent safety features to maintain the plant in a safe condition following assumed accidents without requiring operator action. This paper provides a description of the principal features that were incorporated into the design to achieve low cost and inherent safety

  10. Inherent polarization entanglement generated from a monolithic semiconductor chip

    DEFF Research Database (Denmark)

    Horn, Rolf T.; Kolenderski, Piotr; Kang, Dongpeng

    2013-01-01

    Creating miniature chip scale implementations of optical quantum information protocols is a dream for many in the quantum optics community. This is largely because of the promise of stability and scalability. Here we present a monolithically integratable chip architecture upon which is built...... a photonic device primitive called a Bragg reflection waveguide (BRW). Implemented in gallium arsenide, we show that, via the process of spontaneous parametric down conversion, the BRW is capable of directly producing polarization entangled photons without additional path difference compensation, spectral...... as a serious contender on which to build large scale implementations of optical quantum processing devices....

  11. Chlorophyll-a Algorithms for Oligotrophic Oceans: A Novel Approach Based on Three-Band Reflectance Difference

    Science.gov (United States)

    Hu, Chuanmin; Lee, Zhongping; Franz, Bryan

    2011-01-01

    A new empirical algorithm is proposed to estimate surface chlorophyll-a concentrations (Chl) in the global ocean for Chl less than or equal to 0.25 milligrams per cubic meters (approximately 77% of the global ocean area). The algorithm is based on a color index (CI), defined as the difference between remote sensing reflectance (R(sub rs), sr(sup -1) in the green and a reference formed linearly between R(sub rs) in the blue and red. For low Chl waters, in situ data showed a tighter (and therefore better) relationship between CI and Chl than between traditional band-ratios and Chl, which was further validated using global data collected concurrently by ship-borne and SeaWiFS satellite instruments. Model simulations showed that for low Chl waters, compared with the band-ratio algorithm, the CI-based algorithm (CIA) was more tolerant to changes in chlorophyll-specific backscattering coefficient, and performed similarly for different relative contributions of non-phytoplankton absorption. Simulations using existing atmospheric correction approaches further demonstrated that the CIA was much less sensitive than band-ratio algorithms to various errors induced by instrument noise and imperfect atmospheric correction (including sun glint and whitecap corrections). Image and time-series analyses of SeaWiFS and MODIS/Aqua data also showed improved performance in terms of reduced image noise, more coherent spatial and temporal patterns, and consistency between the two sensors. The reduction in noise and other errors is particularly useful to improve the detection of various ocean features such as eddies. Preliminary tests over MERIS and CZCS data indicate that the new approach should be generally applicable to all existing and future ocean color instruments.

  12. "A Fiber Optic Ethernet With Inherent Migration Capability To FDDI"

    Science.gov (United States)

    Ferris, Kenneth D.; Chan, Tammy S.

    1988-12-01

    A Local Area Network (LAN) designed to a standard commercial interface, the Institute of Electrical and Electronics Engineers (IEEE) 802.3 or Ethernet, has been developed using fiber optics as the physical medium. The LAN, WhisperNet, operates in an active ring and thus has an inherent low cost migration path to a Fiber Distributed Data Interface (FDDI) implementation.

  13. The distribution of inherent phosphorus in fifteen water treatment ...

    African Journals Online (AJOL)

    The aim of this investigation was to characterise the chemical properties relevant to P-sorption/desorption processes of 15 South African WTR and to determine the inherent distribution of P within the WTR using a chemical fractionation procedure. The pH, exchangeable Ca and organic carbon content ranged from 4.77 to ...

  14. The application of probabilistic risk assessment to inherently safe reactors

    International Nuclear Information System (INIS)

    Cave, L.; Kastenberg, W.E.

    1987-01-01

    In the development of safety goals and design criteria for 'inherently safe' reactors a question which arises is 'To what extent is PRA relevant.' To answer this question it is necessary to consider both the risk to the public and the investment risk to the utility. In this paper the factors which are likely to determine safety objectives and their allocation are presented. (orig.)

  15. Influence of Inherent Moisture Content on the Deformation ...

    African Journals Online (AJOL)

    Influence of Inherent Moisture Content on the Deformation. Properties of Coconut Tissues During Mechanical Oil. Expression. *J. J. Mpagalile1 and B. Clarke2. 1Department of ... The study confirmed that moisture content has an important role in the deformation of coconut ..... A micro penetration technique for mechanical.

  16. Tactical supply chain planning models with inherent flexibility

    DEFF Research Database (Denmark)

    Esmaeilikia, Masoud; Fahimnia, Behnam; Sarkis, Joeseph

    2016-01-01

    Supply chains (SCs) can be managed at many levels. The use of tactical SC planning models with multiple flexibility options can help manage the usual operations efficiently and effectively, whilst improve the SC resiliency in response to inherent environmental uncertainties. This paper defines ta...

  17. Total reflection x-ray fluorescence (TXRF) - a tool to obtain information about different air masses and air pollution

    International Nuclear Information System (INIS)

    Schmeling, M.

    2000-01-01

    Aerosols are solid particles dissolved in the atmosphere and have strong influence in the earth climate. Their solid surfaces are the only atmospheric medium for condensation of water leading to cloud formation and ultimately to precipitation. Besides their role in cloud formation, the elemental composition of aerosols reveals useful information about air masses and their transport patterns as well as air pollution. The elemental composition can be considered like a fingerprint of an air mass telling the story about its origin and fate. The presence of Al, Ti and Fe for instance indicates a source located in a highly exposed soil or often desert region, whereas Ni, V and Pb can be traced back to anthropogenic activities like fuel combustion or industrial processes. Other important source regions are the oceans, which emit the main aerosol constituents Na, Cl, and S. The concentrations of these elements in the atmosphere are extremely low and long sampling times are necessary to gain reliable results with most of the common analysis techniques. In contrast to this total reflection x-ray fluorescence (TXRF), as a technique capable to cope with tiny sample amounts, offers the unique possibility to reduce collection times to a minimum of minutes to hours. Such short sampling times in turn render it possible to monitor different air masses either passing through a ground based station or -in the ideal case- flown into by a small research aircraft. Different aerosol samples were taken by aircraft during the second aerosol characterization experiment (ACE-2) with sampling times ranging from 15 minutes up to one hour. These filter samples were analyzed by TXRF for trace elements subsequently. Together with background information about back trajectories and size distribution covering the time of sampling the presence of different air masses could be detected. In another project, short-term samples in the Chicago/Lake Michigan area are collected to study the air mass

  18. Systemic and local anti-Mullerian hormone reflects differences in the reproduction potential of Zebu and European type cattle.

    Science.gov (United States)

    Stojsin-Carter, Anja; Mahboubi, Kiana; Costa, Nathalia N; Gillis, Daniel J; Carter, Timothy F; Neal, Michael S; Miranda, Moyses S; Ohashi, Otavio M; Favetta, Laura A; King, W Allan

    2016-04-01

    This study was conducted to evaluate plasma anti-Mullerian hormone (Pl AMH), follicular fluid AMH (FF AMH) and granulosa cell AMH transcript (GC AMH) levels and their relationships with reproductive parameters in two cattle subspecies, Bos taurus indicus (Zebu), and Bos taurus taurus (European type cattle). Two-dimensional ultrasound examination and serum collection were performed on Zebu, European type and crossbreed cows to determine antral follicle count (AFC), ovary diameter (OD) and Pl AMH concentration. Slaughterhouse ovaries for Zebu and European type cattle were collected to determine FF AMH concentrations, GC AMH RNA levels, AFC, oocyte number, cleavage and blastocyst rate. Additionally GC AMH receptor 2 (AMHR2) RNA level was measured for European type cattle. Relationship between AMH and reproductive parameters was found to be significantly greater in Zebu compared to European cattle. Average Pl AMH mean ± SE for Zebu and European cattle was 0.77 ± 0.09 and 0.33 ± 0.24 ng/ml respectively (p = 0.01), whereas average antral FF AMH mean ± SE for Zebu and European cattle was 4934.3 ± 568.5 and 2977.9 ± 214.1 ng/ml respectively (p cattle. Levels of GC AMHR2 RNA in European cattle were correlated to oocyte number (p = 0.01). Crossbred animals were found more similar to their maternal Zebu counterparts with respect to their Pl AMH to AFC and OD relationships. These results demonstrate that AMH reflects differences between reproduction potential of the two cattle subspecies therefore can potentially be used as a reproductive marker. Furthermore these results reinforce the importance of separately considering the genetic backgrounds of animals when collecting or interpreting bovine AMH data for reproductive performance. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Flow-mediated dilation and peripheral arterial tonometry are disturbed in preeclampsia and reflect different aspects of endothelial function.

    Science.gov (United States)

    Mannaerts, Dominique; Faes, Ellen; Goovaerts, Inge; Stoop, Tibor; Cornette, Jerome; Gyselaers, Wilfried; Spaanderman, Marc; Van Craenenbroeck, Emeline M; Jacquemyn, Yves

    2017-11-01

    Endothelial function and arterial stiffness are known to be altered in preeclamptic pregnancies. Previous studies have shown conflicting results regarding the best technique for assessing vascular function in pregnancy. In this study, we made a comprehensive evaluation of in vivo vascular function [including flow-mediated dilatation (FMD), peripheral arterial tonometry (PAT), and arterial stiffness] in preeclamptic patients and compared them with normal pregnancies. In addition, we assessed the relation between vascular function and systemic inflammation. Fourteen patients with preeclampsia (PE) and 14 healthy pregnant controls were included. Endothelial function was determined by FMD and PAT and arterial stiffness by carotid-femoral pulse-wave velocity and augmentation index. Systemic inflammation was assessed using mean platelet volume (MPV) and neutrophil-lymphocyte ratio (NLR). The reactive hyperemia index, assessed using PAT, is decreased at the third trimester compared with the first trimester in a normal, uncomplicated pregnancy ( P = 0.001). Arterial stiffness is significantly higher in PE versus normal pregnancy ( P function, obtained by FMD, is deteriorated in PE versus normal pregnancy ( P = 0.015), whereas endothelial function assessment by PAT is improved in PE versus normal pregnancy ( P = 0.001). Systemic inflammation (MPV and NLR) increases during normal pregnancy. FMD and PAT are disturbed in PE. Endothelial function, assessed by FMD and PAT, shows distinct results. This may indicate that measurements with FMD and PAT reflect different aspects of endothelial function and that PAT should not be used as a substitute for FMD as a measure of endothelial function in pregnancy. Copyright © 2017 the American Physiological Society.

  20. Production and release of acylcarnitines by primary myotubes reflect the differences in fasting fat oxidation of the donors.

    Science.gov (United States)

    Wolf, Magnus; Chen, Shili; Zhao, Xinjie; Scheler, Mika; Irmler, Martin; Staiger, Harald; Beckers, Johannes; de Angelis, Martin Hrabé; Fritsche, Andreas; Häring, Hans-Ulrich; Schleicher, Erwin D; Xu, Guowang; Lehmann, Rainer; Weigert, Cora

    2013-06-01

    Acylcarnitines are biomarkers of incomplete β-oxidation and mitochondrial lipid overload but indicate also high rates of mitochondrial fatty acid oxidation. It is unknown whether the production of acylcarnitines in primary human myotubes obtained from lean, metabolically healthy subjects reflects the fat oxidation in vivo. Our objective was to quantify the acylcarnitine production in myotubes obtained from subjects with low and high fasting respiratory quotient (RQ). Fasting RQ was determined by indirect calorimetry. Muscle biopsies from the vastus lateralis muscle were taken from 6 subjects with low fasting RQ (mean 0.79 ± 0.03) and 6 with high fasting RQ (0.90 ± 0.03), and satellite cells were isolated, cultured, and differentiated to myotubes. Myotubes were cultivated with 125 μM (13)C-labeled palmitate for 30 minutes and 4 and 24 hours. Quantitative profiling of 42 intracellular and 31 extracellular acylcarnitines was performed by stable isotope dilution-based metabolomics analysis by liquid chromatography coupled to mass spectrometry. Myotubes from donors with high fasting RQ produced and released significant higher amounts of medium-chain acylcarnitines. High (13)C8 and (13)C10 acylcarnitine levels in the extracellular compartment correlated with high fasting RQ. The decreased expression of medium-chain acyl-coenzyme A dehydrogenase (MCAD) in these myotubes can explain the higher rate of incomplete fatty acid oxidation. A lower intracellular [(13)C]acetylcarnitine to carnitine and lower intracellular (13)C16/(13)C18 acylcarnitine to carnitine ratio indicate reduced fatty acid oxidation capacity in these myotubes. Mitochondrial DNA content was not different. Acylcarnitine production and release from primary human myotubes of donors with high fasting RQ indicate a reduced fatty acid oxidation capacity and a higher rate of incomplete fatty acid oxidation. Thus, quantitative profiling of acylcarnitine production in human myotubes can be a suitable tool to

  1. Lévy flight and Brownian search patterns of a free-ranging predator reflect different prey field characteristics.

    Science.gov (United States)

    Sims, David W; Humphries, Nicolas E; Bradford, Russell W; Bruce, Barry D

    2012-03-01

    1. Search processes play an important role in physical, chemical and biological systems. In animal foraging, the search strategy predators should use to search optimally for prey is an enduring question. Some models demonstrate that when prey is sparsely distributed, an optimal search pattern is a specialised random walk known as a Lévy flight, whereas when prey is abundant, simple Brownian motion is sufficiently efficient. These predictions form part of what has been termed the Lévy flight foraging hypothesis (LFF) which states that as Lévy flights optimise random searches, movements approximated by optimal Lévy flights may have naturally evolved in organisms to enhance encounters with targets (e.g. prey) when knowledge of their locations is incomplete. 2. Whether free-ranging predators exhibit the movement patterns predicted in the LFF hypothesis in response to known prey types and distributions, however, has not been determined. We tested this using vertical and horizontal movement data from electronic tagging of an apex predator, the great white shark Carcharodon carcharias, across widely differing habitats reflecting different prey types. 3. Individual white sharks exhibited movement patterns that predicted well the prey types expected under the LFF hypothesis. Shark movements were best approximated by Brownian motion when hunting near abundant, predictable sources of prey (e.g. seal colonies, fish aggregations), whereas movements approximating truncated Lévy flights were present when searching for sparsely distributed or potentially difficult-to-detect prey in oceanic or shelf environments, respectively. 4. That movement patterns approximated by truncated Lévy flights and Brownian behaviour were present in the predicted prey fields indicates search strategies adopted by white sharks appear to be the most efficient ones for encountering prey in the habitats where such patterns are observed. This suggests that C. carcharias appears capable of exhibiting

  2. Inherent reactor power controller for a metal-fueled ALMR

    International Nuclear Information System (INIS)

    Wood, R.T.; Wilson, T.L. Jr.

    1990-01-01

    Inherent power control for metal-fueled ALMR designs involves using reactivity thermal feedback effects to control reactor power. This paper describes how, using classical control design techniques, a control system for normal load following maneuvers was deigned for a pool-type ALMR. This design provides active control of power removal in the balance of plant, direct control of selected primary and intermediate loop temperatures, and passive control of reactor power. The inherent stability of the strong, fast reactivity feedback effects bring heat production in the core into balance with the heat removal system temperatures, which are controlled to meet power demand. A simulation of the control system successfully responded to a 10% step change in power demand by changing power at an acceptable rate without causing large temperature fluctuations or exceeding thermal limits

  3. The Cultural Argument for Understanding Nature of Science. A Chance to Reflect on Similarities and Differences Between Science and Humanities

    Science.gov (United States)

    Reiners, Christiane S.; Bliersbach, Markus; Marniok, Karl

    2017-07-01

    Understanding Nature of Science (NOS) is a central component of scientific literacy, which is agreed upon internationally, and consequently has been a major educational goal for many years all over the globe. In order to justify the promotion of an adequate understanding of NOS, educators have developed several arguments, among them the cultural argument. But what is behind this argument? In order to answer this question, C. P. Snow's vision of two cultures was used as a starting point. In his famous Rede Lecture from 1959, he complained about a wide gap between the arts and humanities on the one hand and sciences on the other hand. While the representatives of the humanities refer to themselves as real intellectuals, the scientists felt rather ignored as a culture, despite the fact that their achievements had been so important for Western society. Thus, Snow argued that as these intellectual cultures were completely different from each other, a mutual understanding was impossible. The first European Regional IHPST Conference took up the cultural view on science again. Thus, the topic of the conference "Science as Culture in the European Context" encouraged us to look at the two cultures and to figure out possibilities to bridge the gap between them in chemistry teacher education. For this reason, we put together three studies—one theoretical and two independent research projects (one dealing with creativity in science, the other with scientific laws and theories) which contribute to our main research field (promoting an understanding of NOS)—in order to address the cultural argument for understanding science from an educational point of view. Among the consented tenets of what understanding NOS implies in an educational context, there are aspects which are associated mainly with the humanities, like the tentativeness of knowledge, creativity, and social tradition, whereas others seem to have a domain-specific meaning, like empirical evidence, theories and laws

  4. On the Meaning of Formative Measurement and How It Differs from Reflective Measurement: Comment on Howell, Breivik, and Wilcox (2007)

    Science.gov (United States)

    Bagozzi, Richard P.

    2007-01-01

    D. Howell, E. Breivik, and J. B. Wilcox (2007) have presented an important and interesting analysis of formative measurement and have recommended that researchers abandon such an approach in favor of reflective measurement. The author agrees with their recommendations but disagrees with some of the bases for their conclusions. He suggests that…

  5. The Disavowal of Difference

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann

    2012-01-01

    In this article the author recounts and reflects upon methodological issues raised in research about class representations and symbolic boundary drawing in face-to-face interview encounters. Although explicit class categories are avoided among the interviewees, particularly for self-identificatio...... the need for paying attention to classed power inherent in the research setting), and the challenges and associated problems of representing the experience of others, especially when researching across difference....

  6. Posttest analysis of the FFTF inherent safety tests

    International Nuclear Information System (INIS)

    Padilla, A. Jr.; Claybrook, S.W.

    1987-01-01

    Inherent safety tests were performed during 1986 in the 400-MW (thermal) Fast Flux Test Facility (FFTF) reactor to demonstrate the effectiveness of an inherent shutdown device called the gas expansion module (GEM). The GEM device provided a strong negative reactivity feedback during loss-of-flow conditions by increasing the neutron leakage as a result of an expanding gas bubble. The best-estimate pretest calculations for these tests were performed using the IANUS plant analysis code (Westinghouse Electric Corporation proprietary code) and the MELT/SIEX3 core analysis code. These two codes were also used to perform the required operational safety analyses for the FFTF reactor and plant. Although it was intended to also use the SASSYS systems (core and plant) analysis code, the calibration of the SASSYS code for FFTF core and plant analysis was not completed in time to perform pretest analyses. The purpose of this paper is to present the results of the posttest analysis of the 1986 FFTF inherent safety tests using the SASSYS code

  7. On the maximum entropy distributions of inherently positive nuclear data

    Energy Technology Data Exchange (ETDEWEB)

    Taavitsainen, A., E-mail: aapo.taavitsainen@gmail.com; Vanhanen, R.

    2017-05-11

    The multivariate log-normal distribution is used by many authors and statistical uncertainty propagation programs for inherently positive quantities. Sometimes it is claimed that the log-normal distribution results from the maximum entropy principle, if only means, covariances and inherent positiveness of quantities are known or assumed to be known. In this article we show that this is not true. Assuming a constant prior distribution, the maximum entropy distribution is in fact a truncated multivariate normal distribution – whenever it exists. However, its practical application to multidimensional cases is hindered by lack of a method to compute its location and scale parameters from means and covariances. Therefore, regardless of its theoretical disadvantage, use of other distributions seems to be a practical necessity. - Highlights: • Statistical uncertainty propagation requires a sampling distribution. • The objective distribution of inherently positive quantities is determined. • The objectivity is based on the maximum entropy principle. • The maximum entropy distribution is the truncated normal distribution. • Applicability of log-normal or normal distribution approximation is limited.

  8. Safety assessment in plant layout design using indexing approach: implementing inherent safety perspective. Part 1 - guideword applicability and method description.

    Science.gov (United States)

    Tugnoli, Alessandro; Khan, Faisal; Amyotte, Paul; Cozzani, Valerio

    2008-12-15

    Layout planning plays a key role in the inherent safety performance of process plants since this design feature controls the possibility of accidental chain-events and the magnitude of possible consequences. A lack of suitable methods to promote the effective implementation of inherent safety in layout design calls for the development of new techniques and methods. In the present paper, a safety assessment approach suitable for layout design in the critical early phase is proposed. The concept of inherent safety is implemented within this safety assessment; the approach is based on an integrated assessment of inherent safety guideword applicability within the constraints typically present in layout design. Application of these guidewords is evaluated along with unit hazards and control devices to quantitatively map the safety performance of different layout options. Moreover, the economic aspects related to safety and inherent safety are evaluated by the method. Specific sub-indices are developed within the integrated safety assessment system to analyze and quantify the hazard related to domino effects. The proposed approach is quick in application, auditable and shares a common framework applicable in other phases of the design lifecycle (e.g. process design). The present work is divided in two parts: Part 1 (current paper) presents the application of inherent safety guidelines in layout design and the index method for safety assessment; Part 2 (accompanying paper) describes the domino hazard sub-index and demonstrates the proposed approach with a case study, thus evidencing the introduction of inherent safety features in layout design.

  9. The size control of silver nanocrystals with different polyols and its application to low-reflection coating materials

    Energy Technology Data Exchange (ETDEWEB)

    Park, Keum Hwan; Park, O Ok [Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 305-701 (Korea, Republic of); Im, Sang Hyuk, E-mail: imromy@krict.re.kr, E-mail: ookpark@kaist.ac.kr [Korea Research Institute of Chemical Technology (KRICT), 19 Singsungno, Yuseong-gu, Daejeon 305-600 (Korea, Republic of)

    2011-01-28

    The size of silver nanocrystals in polyol synthesis can be simply controlled by tuning the viscosity of the reaction medium such as ethylene glycol, 1,2-propanediol, 1,4-butanediol and 1,5-pentanediol. We found that a higher viscose medium (1,5-pentanediol) led to monodispersed smaller particles thanks to the slow addition of silver atoms into the nuclei. Size-controlled silver nanocrystals of 30 nm were obtained in a viscosity controlled medium of 1,5-pentanediol to synthesize a low refractive index filler by coating with silica and subsequent etching of the silver core. The coated low-reflection layer from the hollow silica nanoparticles on polyethylene terephthalate (PET) film can greatly reduce the reflection of the PET film from 10% to 2% over the entire visible region.

  10. Predicting ambient aerosol thermal-optical reflectance (TOR) measurements from infrared spectra: extending the predictions to different years and different sites

    Science.gov (United States)

    Reggente, Matteo; Dillner, Ann M.; Takahama, Satoshi

    2016-02-01

    Organic carbon (OC) and elemental carbon (EC) are major components of atmospheric particulate matter (PM), which has been associated with increased morbidity and mortality, climate change, and reduced visibility. Typically OC and EC concentrations are measured using thermal-optical methods such as thermal-optical reflectance (TOR) from samples collected on quartz filters. In this work, we estimate TOR OC and EC using Fourier transform infrared (FT-IR) absorbance spectra from polytetrafluoroethylene (PTFE Teflon) filters using partial least square regression (PLSR) calibrated to TOR OC and EC measurements for a wide range of samples. The proposed method can be integrated with analysis of routinely collected PTFE filter samples that, in addition to OC and EC concentrations, can concurrently provide information regarding the functional group composition of the organic aerosol. We have used the FT-IR absorbance spectra and TOR OC and EC concentrations collected in the Interagency Monitoring of PROtected Visual Environments (IMPROVE) network (USA). We used 526 samples collected in 2011 at seven sites to calibrate the models, and more than 2000 samples collected in 2013 at 17 sites to test the models. Samples from six sites are present both in the calibration and test sets. The calibrations produce accurate predictions both for samples collected at the same six sites present in the calibration set (R2 = 0.97 and R2 = 0.95 for OC and EC respectively), and for samples from 9 of the 11 sites not included in the calibration set (R2 = 0.96 and R2 = 0.91 for OC and EC respectively). Samples collected at the other two sites require a different calibration model to achieve accurate predictions. We also propose a method to anticipate the prediction error; we calculate the squared Mahalanobis distance in the feature space (scores determined by PLSR) between new spectra and spectra in the calibration set. The squared Mahalanobis distance provides a crude method for assessing the

  11. Understanding the Spatiotemporal Variability of Inherent Water Use Efficiency

    Science.gov (United States)

    Boese, Sven; Jung, Martin; Carvalhais, Nuno; Reichstein, Markus

    2015-04-01

    The global carbon and water cycles are coupled via plant physiology. However, the resulting spatial and temporal covariability of both fluxes on a global scale lacks sufficient understanding. This is required to estimate the impact of atmospheric drought on photosynthesis in water-limited ecosystems. Water use efficiency (WUE) is an essential ecosystem diagnostic defined as the ratio between gross primary productivity (GPP) and transpiration (T). WUE is known to vary with vapour-pressure deficit (VPD) and therefore also in time. The inherent water use efficiency (iWUE) accounts for the VPD effect on WUE and aims at representing a largely time-invariant ecosystem property. However, different ways of describing the functional response of iWUE to VPD are found in the literature. One established iWUE definition was proposed by Beer et al. (2009) and takes the form of iWUE = GPP--VPD- . T (1) A similar definition can be derived from stomatal conductance theories such as Katul et al. (2010) and takes the form of √ -- GPP---VPD- iWUE = T . (2) Here, we use eddy covariance measurements from the FLUXNET database to evaluate both approaches for a globally representative set of biomes including tropical, temperate and semi-arid ecosystems. Testing both definitions in a model-data fusion setup indicated that (2) is more consistent with FLUXNET observations than (1). However, there still remains considerable temporal variability of iWUE which is linked to seasonal changes in VPD. To explore up to which extent the temporal variability of iWUE may be related to the prescribed functional responses to VPD, we treated the exponent of VPD as a global parameter, here termed γ. When γ = 1 the functional response is equivalent to (1), while when γ = 0.5 it corresponds to formulation of model (2)). The global estimate was found to be significantly lower than 0.5, which would have been expected from stomatal conductance theory at leaf level. We assessed whether adding γ as site

  12. On Reflection

    DEFF Research Database (Denmark)

    Blasco, Maribel

    2012-01-01

    produces: that the self is accessible and transcendable, that reflexivity is universal across space and time, and that the self can act as its own remedial change agent or ‘inner consultant.’ I argue that because reflexivity is understood in many different ways, attention to definition is crucial, both...... on the concepts of selfhood that prevail and how notions of difference are constructed. First, I discuss how the dominant usages of reflexivity in intercultural education reflect and reproduce a Cartesian view of the self that shapes how ICC is conceptualized and taught. I discuss three assumptions that this view...

  13. Inherent Conservatism in Deterministic Quasi-Static Structural Analysis

    Science.gov (United States)

    Verderaime, V.

    1997-01-01

    The cause of the long-suspected excessive conservatism in the prevailing structural deterministic safety factor has been identified as an inherent violation of the error propagation laws when reducing statistical data to deterministic values and then combining them algebraically through successive structural computational processes. These errors are restricted to the applied stress computations, and because mean and variations of the tolerance limit format are added, the errors are positive, serially cumulative, and excessively conservative. Reliability methods circumvent these errors and provide more efficient and uniform safe structures. The document is a tutorial on the deficiencies and nature of the current safety factor and of its improvement and transition to absolute reliability.

  14. Inherently safe nuclear-driven internal combustion engines

    International Nuclear Information System (INIS)

    Alesso, P.; Chow, Tze-Show; Condit, R.; Heidrich, J.; Pettibone, J.; Streit, R.

    1991-01-01

    A family of nuclear driven engines is described in which nuclear energy released by fissioning of uranium or plutonium in a prompt critical assembly is used to heat a working gas. Engine performance is modeled using a code that calculates hydrodynamics, fission energy production, and neutron transport self-consistently. Results are given demonstrating a large negative temperature coefficient that produces self-shutoff of energy production. Reduced fission product inventory and the self-shutoff provide inherent nuclear safety. It is expected that nuclear engine reactor units could be scaled from 100 MW on up. 7 refs., 3 figs

  15. Inherent security benefits of underground dry storage of nuclear materials

    International Nuclear Information System (INIS)

    Moore, R.D.; Zahn, T.

    1997-07-01

    This paper, augmented by color slides and handouts, will examine the inherent security benefits of underground dry storage of nuclear materials. Specific items to be presented include: the successful implementation of this type of storage configuration at Argonne National Laboratory - West; facility design concepts with security as a primary consideration; physical barriers achieved by container design; detection, assessment, and monitoring capabilities; and open-quotes self protectionclose quotes strategies. This is a report on the security features of such a facility. The technical operational aspects of the facility are beyond the scope of this paper

  16. Inherent and antigen-induced airway hyperreactivity in NC mice

    OpenAIRE

    Tetsuto Kobayashi; Toru Miura; Tomoko Haba; Miyuki Sato; Masao Takei; Isao Serizawa

    1999-01-01

    In order to clarify the airway physiology of NC mice, the following experiments were carried out. To investigate inherent airway reactivity, we compared tracheal reactivity to various chemical mediators in NC, BALB/c, C57BL/6 and A/J mice in vitro. NC mice showed significantly greater reactivity to acetylcholine than BALB/c and C57BL/6 mice and a reactivity comparable to that of A/J mice, which are known as high responders. Then, airway reactivity to acetylcholine was investigated in those st...

  17. Plants status monitor: Modelling techniques and inherent benefits

    International Nuclear Information System (INIS)

    Breeding, R.J.; Lainoff, S.M.; Rees, D.C.; Prather, W.A.; Fickiessen, K.O.E.

    1987-01-01

    The Plant Status Monitor (PSM) is designed to provide plant personnel with information on the operational status of the plant and compliance with the plant technical specifications. The PSM software evaluates system models using a 'distributed processing' technique in which detailed models of individual systems are processed rather than by evaluating a single, plant-level model. In addition, development of the system models for PSM provides inherent benefits to the plant by forcing detailed reviews of the technical specifications, system design and operating procedures, and plant documentation. (orig.)

  18. The minimum attention plant inherent safety through LWR simplification

    International Nuclear Information System (INIS)

    Turk, R.S.; Matzie, R.A.

    1987-01-01

    The Minimum Attention Plant (MAP) is a unique small LWR that achieves greater inherent safety, improved operability, and reduced costs through design simplification. The MAP is a self-pressurized, indirect-cycle light water reactor with full natural circulation primary coolant flow and multiple once-through steam generators located within the reactor vessel. A fundamental tenent of the MAP design is its complete reliance on existing LWR technology. This reliance on conventional technology provides an extensive experience base which gives confidence in judging the safety and performance aspects of the design

  19. Inherent overload protection for the series resonant converter

    Science.gov (United States)

    King, R. J.; Stuart, T. A.

    1983-01-01

    The overload characteristics of the full bridge series resonant power converter are considered. This includes analyses of the two most common control methods presently in use. The first of these uses a current zero crossing detector to synchronize the control signals and is referred to as the alpha controller. The second is driven by a voltage controlled oscillator and is referred to as the gamma controller. It is shown that the gamma controller has certain reliability advantages in that it can be designed with inherent short circuit protection. Experimental results are included for an 86 kHz converter using power metal-oxide-semiconductor field-effect transistors (MOSFETs).

  20. A workflow for sub-/seismic structure and deformation quantification of 3-D reflection seismic data sets across different scales

    Energy Technology Data Exchange (ETDEWEB)

    Krawczyk, C.M.; Lohr, T.; Oncken, O. [GFZ Potsdam (Germany); Tanner, D.C. [Goettingen Univ. (Germany). GZG; Endres, H. [RWTH Aachen (Germany)]|[TEEC, Isernhagen (Germany); Trappe, H.; Kukla, P. [TEEC, Isernhagen (Germany)

    2007-09-13

    The evolution of a sedimentary basin is mostly affected by deformation. Large-scale, subsurface deformation is typically identified by seismic data, sub-seismic small-scale fractures by well data. Between these two methods, we lack a deeper understanding of how deformation scales. We analysed a 3-D reflection seismic data set in the North German Basin, in order to determine the magnitude and distribution of deformation and its accumulation in space and time. A five-step approach is introduced for quantitative deformation and fracture prediction. An increased resolution of subtle tectonic lineaments is achieved by coherency processing, allowing to unravel the kinematics in the North German Basin from structural interpretation. Extensional events during basin initiation and later inversion are evident. 3-D retrodeformation shows major-strain magnitudes between 0-20% up to 1.3 km away from a fault trace, and variable deviations of associated extensional fractures. Good correlation of FMI data, strain distribution from retro-deformation and from geostatistic tools (see also Trappe et al., this volume) allows the validation of the results and makes the prediction of small-scale faults/fractures possible. The temporal component will be gained in the future by analogue models. The suggested workflow is applicable to reflection seismic surveys and yields in great detail both the tectonic history of a region as well as predictions for hydrocarbon plays or deep groundwater or geothermal reservoirs. (orig.)

  1. [Reflection on the Differences and Similarities of Mental Health Care in Virginia and Taiwan: Geography, History, Culture, and Nurse Practitioners].

    Science.gov (United States)

    Lu, Chueh-Fen; Tung, Ching-Chuan; Ely, Linda

    2016-12-01

    Sponsored by the pilot overseas internships project of the Ministry of Education, Taiwan, the authors and ten undergraduate students from Taiwan visited several mental health facilities in Virginia for one month. These facilities included the Catawba State Hospital, Salem Veteran Affairs Medical Center, Carilion Saint Albans Behavioral Health (New River Valley Medical Center), Warm Hearth Village, Adult & Child Family Counseling private outpatient clinic, the Free Clinic of the New River Valley, New Life Clubhouse, and Self-Government Program for Assertive Community Treatment. In-depth dialogue and participation in nursing care under the supervision of registered nurses facilitated the authors' reflection on mental health care and the roles and functions of Taiwanese nurse practitioners. The present article adopts a macro view in order to compare the related issues between Taiwan and Virginia, including: geographic features, history, culture of health-seeking behavior, healthcare insurance, and the relationships among various professionals. How these issues relate to social-cultural background and how the overall healthcare environment impacts upon the roles of nurse practitioners in Taiwan are rarely discussed in literature. We expect that this cross-cultural contrast and reflection will elicit a better understanding of how these factors have shaped and affected the roles of Taiwanese nurse practitioners. Further, suggestions about how to improve the nursing profession in Taiwan are presented.

  2. FT-IR reflection spectra of single crystals: resolving phonons of different symmetry without using polarised radiation

    Directory of Open Access Journals (Sweden)

    METODIJA NAJDOSKI

    2000-07-01

    Full Text Available Fourier-transform infrared (FT-IR reflection spectra, asquired at nearnormal incidence, were recorded from single crystals belonging to six crystal systems: CsCr(SO42.12H2O (alum, cubic, K2CuCl2·2H2O (Mitscherlichite, tetragonal, CaCO3 (calcite, hexagonal, KHSO4 (mercallite, orthorhombic, CaSO4·2H2O (gypsum, monoclinic and CuSO4·5H2O (chalcantite, triclinic. The acquired IR reflection spectra were further transformed into absorption spectra, employing the Kramers-Kronig transformation. Except for the cubic alums, the spectra strongly depend on the crystal face from which they were recorded; this is a consequence of anisotropy. Phonons of a given symmetry (E-species, in tetragonal/hexagonal and B-species, in monoclinic crystals may be resolved without using a polariser. The spectrum may be simplified in the case of an orthorhombic crystal, as well. The longitudinal-optical (LO and transversal-optical (TO mode frequencies were calculated in the case of optically isotropic and the simplified spectra of optically uniaxial crystals.

  3. Basis, evidences and consequences of the inherent stellar encocooning

    CERN Document Server

    Celis, L

    2002-01-01

    Based on 7093 observations with photoelectrical photometrical measurements of 191 Mira stars, the following equations (from the papers [1] to [18]) give the basis to establish the Inherent Stellar Encocooning with the spectro-photometric characteristics of the red giant variable stars, especially the Miras, which have large amplitudes (approx 50% of giant variables). The specific basis that justifies a progressive covering with ionized molecules, cold gases, dust and grains are: The relation of the visual amplitudes A sub v =A sub r +E sub A whose real luminosity separate the intrinsic pulsation and amplitude excess effects due to the presence of molecules [145] and an opaque envelope of cool gases; The relation of the visual absolute magnitudes M sub v =M sub v sub r (P)+M sub a (delta sub T sub i sub O V) which is affected by an inherent absorption and/or occultation, and; The relation that defines the probable absolute luminosity and depends on the period and the (Sa) spectral type at maximum M sub v =-2.2...

  4. Inherent and antigen-induced airway hyperreactivity in NC mice

    Directory of Open Access Journals (Sweden)

    Tetsuto Kobayashi

    1999-01-01

    Full Text Available In order to clarify the airway physiology of NC mice, the following experiments were carried out. To investigate inherent airway reactivity, we compared tracheal reactivity to various chemical mediators in NC, BALB/c, C57BL/6 and A/J mice in vitro. NC mice showed significantly greater reactivity to acetylcholine than BALB/c and C57BL/6 mice and a reactivity comparable to that of A/J mice, which are known as high responders. Then, airway reactivity to acetylcholine was investigated in those strains in vivo. NC mice again showed comparable airway reactivity to that seen in A/J mice and a significantly greater reactivity than that seen in BALB/c and C57BL/6 mice. To investigate the effects of airway inflammation on airway reactivity to acetylcholine in vivo, NC and BALB/c mice were sensitized to and challenged with antigen. Sensitization to and challenge with antigen induced accumulation of inflammatory cells, especially eosinophils, in lung and increased airway reactivity in NC and BALB/c mice. These results indicate that NC mice exhibit inherent and antigen-induced airway hyperreactivity. Therefore, NC mice are a suitable strain to use in investigating the mechanisms underlying airway hyperreactivity and such studies will provide beneficial information for understanding the pathophysiology of asthma.

  5. The inherent catastrophic traps in retrograde CTO PCI.

    Science.gov (United States)

    Wu, Eugene B; Tsuchikane, Etsuo

    2018-05-01

    When we learn to drive, our driving instructor tells us how to check the side mirror and turn your head to check the blind spot before changing lanes. He tells us how to stop at stop signs, how to drive in slippery conditions, the safe stopping distances, and these all make our driving safe. Similarly, when we learn PCI, our mentors teach us to seat the guiding catheter co-axially, to wire the vessel safely, to deliver balloon and stents over the wire, to watch the pressure of the guiding, in order that we perform PCI safely and evade complications. In retrograde CTO PCI, there is no such published teaching. Also many individual mentors have not had the wide experience to see all the possible complications of retrograde CTO PCI and, therefore, may not be able to warn their apprentice. As the number of retrograde procedures increase worldwide, there is a corresponding increase in catastrophic complications, many of which, we as experts, can see are easily avoidable. To breach this gap in knowledge, this article describes 12 commonly met inherent traps in retrograde CTO PCI. They are inherent because by arranging our equipment in the manner to perform retrograde CTO PCI, these complications are either induced directly or happen easily. We hope this work will enhance safety of retrograde CTO PCI and avoid many catastrophic complications for our readers and operators. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  6. Estimates of leaf area index from spectral reflectance of wheat under different cultural practices and solar angle

    Science.gov (United States)

    Asrar, G.; Kanemasu, E. T.; Yoshida, M.

    1985-01-01

    The influence of management practices and solar illumination angle on the leaf area index (LAI) was estimated from measurements of wheat canopy reflectance evaluated by two methods, a regression formula and an indirect technique. The date of planting and the time of irrigation in relation to the stage of plant growth were found to have significant effects on the development of leaves in spring wheat. A reduction in soil moisture adversely affected both the duration and magnitude of the maximum LAI for late planting dates. In general, water stress during vegetative stages resulted in a reduction in maximum LAI, while water stress during the reproductive period shortened the duration of green LAI in spring wheat. Canopy geometry and solar angle also affected the spectral properties of the canopies, and hence the estimated LAI. Increase in solar zenith angles resulted in a general increase in estimated LAI obtained from both methods.

  7. Using mid-Infrared External Reflectance Spectroscopy to Distinguish Between Different Commercially Produced Poly[Methyl MethAcrylate] (PMMA) Samples - A Null Result

    Science.gov (United States)

    Fajardo, Mario; Neel, Christopher; Lacina, David

    2017-06-01

    We report (null) results of experiments testing the hypothesis that mid-infrared (mid-IR) spectroscopy can be used to distinguish samples of poly[methyl methacrylate] (PMMA) obtained from different commercial suppliers. This work was motivated by the desire for a simple non-destructive and non-invasive test for pre-sorting PMMA samples prior to use in shock and high-strain-rate experiments, where PMMA is commonly used as a standard material. We discuss: our choice of mid-IR external reflectance spectroscopy, our approach to recording reflectance spectra at near-normal (θ = 0 + / - 5 degree) incidence and for extracting the wavelength-weighted absorption spectrum from the raw reflectance data via a Kramers-Krönig analysis. We employ extensive signal, which necessitates adopting a special experimental protocol to mitigate the effects of instrumental drift. Finally, we report spectra of three PMMA samples with different commercial pedigrees, and show that they are virtually identical (+ / - 1 % error, 95% confidence); obviating the use of mid-IR reflectance spectroscopy to tell the samples apart.

  8. Inherent optical properties of pollen particles: a case study for the morning glory pollen.

    Science.gov (United States)

    Liu, Chao; Yin, Yan

    2016-01-25

    Biological aerosols, such as bacteria, fungal spores, and pollens, play an important role on various atmospheric processes, whereas their inherent optical property is one of the most uncertainties that limit our ability to assess their effects on weather and climate. A numerical model with core-shell structure, hexagonal grids and barbs is developed to represent one kind of realistic pollen particles, and their inherent optical properties are simulated using a pseudo-spectral time domain method. Both the hexagonal grids and barbs substantially affect the modeled pollen optical properties. Results based on the realistic particle model are compared with two equivalent spherical approximations, and the significant differences indicate the importance of considering pollen geometries for their optical properties.

  9. Searching for Models Exhibiting High Circularly Polarized Luminescence: the Electroactive Inherently Chiral Oligothiophenes.

    Science.gov (United States)

    Benincori, Tiziana; Appoloni, Giulio; Mussini, Patrizia Romana; Arnaboldi, Serena; Cirilli, Roberto; Quartapelle Procopio, Elsa; Panigati, Monica; Abbate, Sergio; Mazzeo, Giuseppe; Longhi, Giovanna

    2018-05-02

    Two new inherently chiral oligothiophenes characterized by the atropisomeric 3,3'-bithianaphtene scaffold functionalized with fused ring bithiophene derivatives, namely 4H-cyclopenta [2,1-b3:4b']dithiophene (CPDT) and dithieno[3,3-b:2',3'-d]pyrrole (DTP), were synthesized. The racemates were fully characterized and resolved into antipodes by enantioselective HPLC. The enantiomers were analyzed through different chiroptical techniques: electronic circular dichroism (ECD) and vibrational circular dichroism (VCD) were employed to attribute the absolute configuration (AC). Comparison of experimental and calculated VCD spectra confirmed the DFT calculated conformational characteristics. The compound functionalized with two CPDT units was oxidized with FeCl3 and ECD and CPL of the resulting material were measured. Circularly Polarized Luminescence (CPL) was measured in order to verify if inherently chiral oligothiophenes could be promising systems for chiral photonics applications. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Central auditory processing. Are the emotional perceptions of those listening to classical music inherent in the composition or acquired by the listeners?

    Science.gov (United States)

    Goycoolea, Marcos; Levy, Raquel; Ramírez, Carlos

    2013-04-01

    There is seemingly some inherent component in selected musical compositions that elicits specific emotional perceptions, feelings, and physical conduct. The purpose of the study was to determine if the emotional perceptions of those listening to classical music are inherent in the composition or acquired by the listeners. Fifteen kindergarten students, aged 5 years, from three different sociocultural groups, were evaluated. They were exposed to portions of five purposefully selected classical compositions and asked to describe their emotions when listening to these musical pieces. All were instrumental compositions without human voices or spoken language. In addition, they were played to an audience of an age at which they were capable of describing their perceptions and supposedly had no significant previous experience of classical music. Regardless of their sociocultural background, the children in the three groups consistently identified similar emotions (e.g. fear, happiness, sadness), feelings (e.g. love), and mental images (e.g. giants or dangerous animals walking) when listening to specific compositions. In addition, the musical compositions generated physical conducts that were reflected by the children's corporal expressions. Although the sensations were similar, the way of expressing them differed according to their background.

  11. Multi-objective optimization of a cascade refrigeration system: Exergetic, economic, environmental, and inherent safety analysis

    International Nuclear Information System (INIS)

    Eini, Saeed; Shahhosseini, Hamidreza; Delgarm, Navid; Lee, Moonyong; Bahadori, Alireza

    2016-01-01

    Highlights: • A multi-objective optimization is performed for a cascade refrigeration cycle. • The optimization problem considers inherently safe design as well as 3E analysis. • As a measure of inherent safety level a quantitative risk analysis is utilized. • A CO 2 /NH 3 cascade refrigeration system is compared with a CO 2 /C 3 H 8 system. - Abstract: Inherently safer design is the new approach to maximize the overall safety of a process plant. This approach suggests some risk reduction strategies to be implemented in the early stages of design. In this paper a multi-objective optimization was performed considering economic, exergetic, and environmental aspects besides evaluation of the inherent safety level of a cascade refrigeration system. The capital costs, the processing costs, and the social cost due to CO 2 emission were considered to be included in the economic objective function. Exergetic efficiency of the plant was considered as the second objective function. As a measure of inherent safety level, Quantitative Risk Assessment (QRA) was performed to calculate total risk level of the cascade as the third objective function. Two cases (ammonia and propane) were considered to be compared as the refrigerant of the high temperature circuit. The achieved optimum solutions from the multi–objective optimization process were given as Pareto frontier. The ultimate optimal solution from available solutions on the Pareto optimal curve was selected using Decision-Makings approaches. NSGA-II algorithm was used to obtain Pareto optimal frontiers. Also, three decision-making approaches (TOPSIS, LINMAP, and Shannon’s entropy methods) were utilized to select the final optimum point. Considering continuous material release from the major equipment in the plant, flash and jet fire scenarios were considered for the CO 2 /C 3 H 8 cycle and toxic hazards were considered for the CO 2 /NH 3 cycle. The results showed no significant differences between CO 2 /NH 3 and

  12. Project of a binary breeder reactor and its inherent safety

    International Nuclear Information System (INIS)

    Nascimento, J.A. do; Dias, A.F.; Ishiguro, Y.

    1983-01-01

    A core layout for the binary breeder reactor (BBR) is developed based on the results of preliminary burnup calculations. In the U 233 /TH fueled inner core, the apparent breeding ratio is low due to the accumulation of Pa-233 in the first few months of operation. The loss of reactivity during this time is approximatelly 3%. The BBR requires more reactivity control than Pu/U-fueled LMFBRs and the core layout developed has 19 control rod assemblies in the inner core. Three aspects related to the inherent safety of the BBR have been studied: radial distribution of the sodium-void reactivity, zone-wise Doppler reactivity, and the delayed neutron fractions. Results show excellent safety characteristics of the BBR. (Author) [pt

  13. Transient behaviour and inherent safety research of LMFBR power plants

    International Nuclear Information System (INIS)

    Zhu Jizhou; Wang Ping; Yu Baoan

    1995-06-01

    Fast Breeder Reactor will be the next generation reactor for nuclear electricity production, the development of FBR will give the profits of efficient utilization of nuclear resources. The fast reactor safety analysis is the foundation and key of FBR research work. Therefore, a block-oriented mathematical model for the primary system of LMFBRs was constructed, and the dynamic simulating results which have been carried out on micro-computer are presented for various transients, i.e. TOP, LOFS, LOHS. The results agree well with the corresponding results of the code NATDEMO and experiment results of EBR-II. Based on previous analysis, various methods are discussed to confirm the inherent safety of LMFBR

  14. Inherent calibration of microdosemeters for dose distributions in lineal energy

    Energy Technology Data Exchange (ETDEWEB)

    Crossman, J.S.P.; Watt, D.E. [Saint Andrews Univ. (United Kingdom). Dept. of Physics and Astronomy

    1994-12-31

    A method, utilising the inherent electron event spectra, is described for the absolute calibration of microdosemeters in the presence of a photon field. The method, which avoids the problems and uncertainties present in conventional calibration techniques, involves simple extrapolation of the dose distribution in lineal energy associated with `exact stopper` electrons. Validation of the method is made using the published experimental distributions of Rossi, of Kliauga, and of Dvorak and by direct theoretical calculation of the components of the microdose distributions for gamma rays. Further experimental data from a cylindrical TEPC in a photon field generated by an external source of {sup 137}Cs are obtained for comparison. A `universal` calibration curve for the dose-weighted lineal energy as a function of the simulated mean diameter of the microdosemeter, is presented for use in practical applications. (author).

  15. Inherent calibration of microdosemeters for dose distributions in lineal energy

    International Nuclear Information System (INIS)

    Crossman, J.S.P.; Watt, D.E.

    1994-01-01

    A method, utilising the inherent electron event spectra, is described for the absolute calibration of microdosemeters in the presence of a photon field. The method, which avoids the problems and uncertainties present in conventional calibration techniques, involves simple extrapolation of the dose distribution in lineal energy associated with 'exact stopper' electrons. Validation of the method is made using the published experimental distributions of Rossi, of Kliauga, and of Dvorak and by direct theoretical calculation of the components of the microdose distributions for gamma rays. Further experimental data from a cylindrical TEPC in a photon field generated by an external source of 137 Cs are obtained for comparison. A 'universal' calibration curve for the dose-weighted lineal energy as a function of the simulated mean diameter of the microdosemeter, is presented for use in practical applications. (author)

  16. Design strategy for control of inherently safe reactors

    International Nuclear Information System (INIS)

    Chisholm, G.H.

    1984-01-01

    Reactor power plant safety is assured through a combination of engineered barriers to radiation release (e.g., reactor containment) in combination with active reactor safety systems to shut the reactor down and remove decay heat. While not specifically identified as safety systems, the control systems responsible for continuous operation of plant subsystems are the first line of defense for mitigating radiation releases and for plant protection. Inherently safe reactors take advantage of passive system features for decay-heat removal and reactor shutdown functions normally ascribed to active reactor safety systems. The advent of these reactors may permit restructuring of the present control system design strategy. This restructuring is based on the fact that authority for protection against unlikely accidents is, as much as practical, placed upon the passive features of the system instead of the traditional placement upon the PPS. Consequently, reactor control may be simplified, allowing the reliability of control systems to be improved and more easily defended

  17. Results of the 1986 FFTF inherent safety tests

    International Nuclear Information System (INIS)

    Burke, T.M.; Campbell, L.R.; Franz, G.R.; Knecht, W.L.

    1987-01-01

    A series of tests was recently completed at the 400-MW (thermal) Fast Flux Test Facility (FFTF) to further demonstrate the passive safety characteristics of liquid-metal-cooled fast reactors. Earlier FFTF testing of decay heat removal by sodium natural circulation was reported in 1981. The main purpose of the 1986 test series was to demonstrate passive reactor shutdown during a loss-of-flow event when several inherent shutdown devices called gas expansion modules (GEMs) were installed in the reactor. However, these tests also provide further data on the natural circulation performance of the primary system, in particular the reactor core, and thus add to the data base available for checking the validity of available analytical tools

  18. Project of a binary breeder reactor and its inherent safety

    International Nuclear Information System (INIS)

    Nascimento, J.A. do; Dias, A.F.; Ishiguro, Y.

    1983-01-01

    A core layout for the binary breeder reactor (BBR) is developed based on the results of preliminary burnup calculations. The apparent breeding ratio, in the U 233 /Th fueled inner core, is low due to the accumulation of Pa-233 in the first few months of operation. The loss of reactivity during this time is around 3%. The BBR requires more reactivity control than Pu/U-fueled LMFBRs and the core layout developed has 19 control rod assemblies in the inner core. Three aspects related to the inherent safety of the Binary Breeder Reactor have been studied: the radial distribution of the sodium-void reactivity zone-wise Doppler reactivity and the fractions of delayed neutrons. The results show excellent characteristics for the BRB safety. (Author) [pt

  19. Contracting for independent evaluation: approaches to an inherent tension.

    Science.gov (United States)

    Klerman, Jacob Alex

    2010-08-01

    There has recently been discussion of whether independent contract evaluation is possible. This article acknowledges the inherent tension in contract evaluation and in response suggests a range of constructive approaches to improving the independence of contract evaluation. In particular, a clear separation between the official evaluation report and a contractor's own publication of analysis from the underlying evaluation appears to be a promising approach. In this approach, the funder would retain almost unfettered rights to the official contract report (including the right never to publish but not the right to change the contractor's text while leaving the contractor's authorship) and the contractor would retain clearly defined rights to publish any findings from the evaluation (subject only to the limitations of human subjects and proprietary data and some minimal notice).

  20. Development of inherent core technologies for advanced reactor

    International Nuclear Information System (INIS)

    Kim, Keung Koo; Noh, J.M.; Hwang, D.H.

    1999-03-01

    Recently, the developed countries made their effort on developing the advanced reactor which will result in significantly enhanced safety and economy. However, they will protect the advanced reactor and its design technology with patent and proprietary right. Therefore, it is very important to develop our own key core concepts and inherent core design technologies which can form a foundation of indigenous technologies for development of the domestic advanced reactor in order to keep the superiority in the nuclear plant building market among the developing countries. In order to provide the basic technology for the core design of advanced reactor, this project is for developing the inherent core design concepts with enhanced safety and economy, and associated methodologies and technologies for core analyses. The feasibility study of constructing domestic critical facilities are performed by surveying the status and utilization of foreign facilities and by investigating the demand for domestic facilities. The research results developed in this project, such as core analysis methodologies for hexagonal core, conceptual core design based on hexagonal fuel assemblies and soluble boron core design and control strategies, will provide a technical foundation in developing core design of domestic advanced reactor. Furthermore, they will strengthen the competitiveness of Korean nuclear technology. We also expect that some of the design concepts developed in this project to improve the reactor safety and economy can be applicable to the design of advanced reactor. This will significantly reduce the public anxiety on the nuclear power plant, and will contribute to the economy of construction and operation for the future domestic reactors. Even though the critical facility will not be constructed right now, the investigation of the status and utilization of foreign critical facility will contribute to the future critical facility construction. (author). 150 refs., 34 tabs., 103

  1. Development of inherent core technologies for advanced reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Keung Koo; Noh, J.M.; Hwang, D.H. [and others

    1999-03-01

    Recently, the developed countries made their effort on developing the advanced reactor which will result in significantly enhanced safety and economy. However, they will protect the advanced reactor and its design technology with patent and proprietary right. Therefore, it is very important to develop our own key core concepts and inherent core design technologies which can form a foundation of indigenous technologies for development of the domestic advanced reactor in order to keep the superiority in the nuclear plant building market among the developing countries. In order to provide the basic technology for the core design of advanced reactor, this project is for developing the inherent core design concepts with enhanced safety and economy, and associated methodologies and technologies for core analyses. The feasibility study of constructing domestic critical facilities are performed by surveying the status and utilization of foreign facilities and by investigating the demand for domestic facilities. The research results developed in this project, such as core analysis methodologies for hexagonal core, conceptual core design based on hexagonal fuel assemblies and soluble boron core design and control strategies, will provide a technical foundation in developing core design of domestic advanced reactor. Furthermore, they will strengthen the competitiveness of Korean nuclear technology. We also expect that some of the design concepts developed in this project to improve the reactor safety and economy can be applicable to the design of advanced reactor. This will significantly reduce the public anxiety on the nuclear power plant, and will contribute to the economy of construction and operation for the future domestic reactors. Even though the critical facility will not be constructed right now, the investigation of the status and utilization of foreign critical facility will contribute to the future critical facility construction. (author). 150 refs., 34 tabs., 103

  2. Experimental evidence for inherent Lévy search behaviour in foraging animals.

    Science.gov (United States)

    Kölzsch, Andrea; Alzate, Adriana; Bartumeus, Frederic; de Jager, Monique; Weerman, Ellen J; Hengeveld, Geerten M; Naguib, Marc; Nolet, Bart A; van de Koppel, Johan

    2015-05-22

    Recently, Lévy walks have been put forward as a new paradigm for animal search and many cases have been made for its presence in nature. However, it remains debated whether Lévy walks are an inherent behavioural strategy or emerge from the animal reacting to its habitat. Here, we demonstrate signatures of Lévy behaviour in the search movement of mud snails (Hydrobia ulvae) based on a novel, direct assessment of movement properties in an experimental set-up using different food distributions. Our experimental data uncovered clusters of small movement steps alternating with long moves independent of food encounter and landscape complexity. Moreover, size distributions of these clusters followed truncated power laws. These two findings are characteristic signatures of mechanisms underlying inherent Lévy-like movement. Thus, our study provides clear experimental evidence that such multi-scale movement is an inherent behaviour rather than resulting from the animal interacting with its environment. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  3. Liver-inherent immune system: its role in blood-stage malaria.

    Science.gov (United States)

    Wunderlich, Frank; Al-Quraishy, Saleh; Dkhil, Mohamed A

    2014-01-01

    The liver is well known as that organ which is obligately required for the intrahepatocyte development of the pre-erythrocytic stages of the malaria-causative agent Plasmodium. However, largely neglected is the fact that the liver is also a central player of the host defense against the morbidity- and mortality-causing blood stages of the malaria parasites. Indeed, the liver is equipped with a unique immune system that acts locally, however, with systemic impact. Its main "antipodal" functions are to recognize and to generate effective immunoreactivity against pathogens on the one hand, and to generate tolerance to avoid immunoreactivity with "self" and harmless substances as dietary compounds on the other hand. This review provides an introductory survey of the liver-inherent immune system: its pathogen recognition receptors including Toll-like receptors (TLRs) and its major cell constituents with their different facilities to fight and eliminate pathogens. Then, evidence is presented that the liver is also an essential organ to overcome blood-stage malaria. Finally, we discuss effector responses of the liver-inherent immune system directed against blood-stage malaria: activation of TLRs, acute phase response, phagocytic activity, cytokine-mediated pro- and anti-inflammatory responses, generation of "protective" autoimmunity by extrathymic T cells and B-1 cells, and T cell-mediated repair of liver injuries mainly produced by malaria-induced overreactions of the liver-inherent immune system.

  4. Safety assessment in plant layout design using indexing approach: Implementing inherent safety perspective

    International Nuclear Information System (INIS)

    Tugnoli, Alessandro; Khan, Faisal; Amyotte, Paul; Cozzani, Valerio

    2008-01-01

    The design of layout plans requires adequate assessment tools for the quantification of safety performance. The general focus of the present work is to introduce an inherent safety perspective at different points of the layout design process. In particular, index approaches for safety assessment and decision-making in the early stages of layout design are developed and discussed in this two-part contribution. Part 1 (accompanying paper) of the current work presents an integrated index approach for safety assessment of early plant layout. In the present paper (Part 2), an index for evaluation of the hazard related to the potential of domino effects is developed. The index considers the actual consequences of possible escalation scenarios and scores or ranks the subsequent accident propagation potential. The effects of inherent and passive protection measures are also assessed. The result is a rapid quantification of domino hazard potential that can provide substantial support for choices in the early stages of layout design. Additionally, a case study concerning selection among various layout options is presented and analyzed. The case study demonstrates the use and applicability of the indices developed in both parts of the current work and highlights the value of introducing inherent safety features early in layout design

  5. The Reflective Learning Continuum: Reflecting on Reflection

    Science.gov (United States)

    Peltier, James W.; Hay, Amanda; Drago, William

    2005-01-01

    The importance of reflection to marketing educators is increasingly recognized. However, there is a lack of empirical research that considers reflection within the context of both the marketing and general business education literature. This article describes the use of an instrument that can be used to measure four identified levels of a…

  6. Quantification of the inherent uncertainty in the relaxation modulus and creep compliance of asphalt mixes

    Science.gov (United States)

    Kassem, Hussein A.; Chehab, Ghassan R.; Najjar, Shadi S.

    2017-08-01

    Advanced material characterization of asphalt concrete is essential for realistic and accurate performance prediction of flexible pavements. However, such characterization requires rigorous testing regimes that involve mechanical testing of a large number of laboratory samples at various conditions and set-ups. Advanced measurement instrumentation in addition to meticulous and accurate data analysis and analytical representation are also of high importance. Such steps as well as the heterogeneous nature of asphalt concrete (AC) constitute major factors of inherent variability. Thus, it is imperative to model and quantify the variability of the needed asphalt material's properties, mainly the linear viscoelastic response functions such as: relaxation modulus, E(t), and creep compliance, D(t). The objective of this paper is to characterize the inherent uncertainty of both E(t) and D(t) over the time domain of their master curves. This is achieved through a probabilistic framework using Monte Carlo simulations and First Order approximations, utilizing E^{*} data for six AC mixes with at least eight replicates per mix. The study shows that the inherent variability, presented by the coefficient of variation (COV), in E(t) and D(t) is low at small reduced times, and increases with the increase in reduced time. At small reduced times, the COV in E(t) and D(t) are similar in magnitude; however, differences become significant at large reduced times. Additionally, the probability distributions and COVs of E(t) and D(t) are mix dependent. Finally, a case study is considered in which the inherent uncertainty in D(t) is forward propagated to assess the effect of variability on the predicted number of cycles to fatigue failure of an asphalt mix.

  7. Variation in prescribing for anxiety and depression: a reflection of health inequalities, cultural differences or variations in access to care?

    OpenAIRE

    Peters Jean; Grimsley Michael; Dibben Chris; Goyder Elizabeth; Blank Lindsay; Ellis Elizabeth

    2006-01-01

    Abstract Background There are large variations in mental health prescribing in UK populations. However the underlying reasons for these differences, which may be related to differences in prevalence, cultural expectations or practical difficulties in access to treatment, remain uncertain. Methods Linear modelling was used to investigate whether population characteristics or access to primary care account for variations in mental health prescribing across 39 deprived neighbourhoods. Results Th...

  8. A model for roll stall and the inherent stability modes of low aspect ratio wings at low Reynolds numbers

    Science.gov (United States)

    Shields, Matt

    The development of Micro Aerial Vehicles has been hindered by the poor understanding of the aerodynamic loading and stability and control properties of the low Reynolds number regime in which the inherent low aspect ratio (LAR) wings operate. This thesis experimentally evaluates the static and damping aerodynamic stability derivatives to provide a complete aerodynamic model for canonical flat plate wings of aspect ratios near unity at Reynolds numbers under 1 x 105. This permits the complete functionality of the aerodynamic forces and moments to be expressed and the equations of motion to solved, thereby identifying the inherent stability properties of the wing. This provides a basis for characterizing the stability of full vehicles. The influence of the tip vortices during sideslip perturbations is found to induce a loading condition referred to as roll stall, a significant roll moment created by the spanwise induced velocity asymmetry related to the displacement of the vortex cores relative to the wing. Roll stall is manifested by a linearly increasing roll moment with low to moderate angles of attack and a subsequent stall event similar to a lift polar; this behavior is not experienced by conventional (high aspect ratio) wings. The resulting large magnitude of the roll stability derivative, Cl,beta and lack of roll damping, Cl ,rho, create significant modal responses of the lateral state variables; a linear model used to evaluate these modes is shown to accurately reflect the solution obtained by numerically integrating the nonlinear equations. An unstable Dutch roll mode dominates the behavior of the wing for small perturbations from equilibrium, and in the presence of angle of attack oscillations a previously unconsidered coupled mode, referred to as roll resonance, is seen develop and drive the bank angle? away from equilibrium. Roll resonance requires a linear time variant (LTV) model to capture the behavior of the bank angle, which is attributed to the

  9. Cultural inter-population differences do not reflect biological distances: an example of interdisciplinary analysis of populations from Eastern Adriatic coast.

    Science.gov (United States)

    Bašić, Željana; Fox, Ayano R; Anterić, Ivana; Jerković, Ivan; Polašek, Ozren; Anđelinović, Šimun; Holland, Mitchell M; Primorac, Dragan

    2015-06-01

    To compare the population group from the Šopot graveyard with population groups from traditional Croatian medieval graveyards by using anthropological, craniometrics, and mitochondrial (mtDNA) analysis and to examine if the cultural differences between population groups reflect biological differences. We determined sex, age at death, pathological, and traumatic changes of skeletal remains from the Šopot graveyard and compared them with a cumulative medieval sample from the same region. We also performed principal component analysis to compare skeletal remains from Šopot with those from Ostrovica and other Central European samples according to 8 cranial measurements. Finally, we compared 46 skeletons from Šopot with medieval (Ostrovica) and contemporary populations using mDNA haplogroup profiling. The remains from Šopot were similar to the cumulative sample in lifestyle and quality of life markers. Principal component analysis showed that they were closely related to Eastern Adriatic coast sites (including Ostrovica and Šopot) in terms of cranial morphology, indicating similar biological makeup. According to mDNA testing, Šopot population showed no significant differences in the haplogroup prevalence from either medieval or contemporary populations. This study shows that the Šopot population does not significantly differ from other medieval populations from this area. Besides similar quality of life markers, these populations also had similar biological markers. Substantial archeological differences can therefore be attributed to apparent cultural influences, which in this case do not reflect biological differences.

  10. New analyses of the National Institute of Mental Health Treatment of Depression Collaborative Research Program: do different treatments reflect different processes?

    Science.gov (United States)

    Herbert, Gregory L; Callahan, Jennifer; Ruggero, Camilo J; Murrell, Amy R

    2013-01-01

    To determine whether or not different therapies have distinct patterns of change, it is useful to investigate not only the end result of psychotherapy (outcome) but also the processes by which outcomes are attained. The present study subjected data from the National Institute of Mental Health Treatment of Depression Collaborative Research Program to survival analyses to examine whether the process of psychotherapy, as conceptualized by the phase model, differed between psychotherapy treatment approaches. Few differences in terms of progression through phases of psychotherapy were identified between cognitive behavior therapy and interpersonal therapy. Additionally, results indicate that phases of psychotherapy may not represent discrete, sequentially invariant processes.

  11. Age Differences in Brain Activity during Emotion Processing: Reflections of Age-Related Decline or Increased Emotion Regulation?

    OpenAIRE

    Nashiro, Kaoru; Sakaki, Michiko; Mather, Mara

    2011-01-01

    Despite the fact that physical health and cognitive abilities decline with aging, the ability to regulate emotion remains stable and in some aspects improves across the adult life span. Older adults also show a positivity effect in their attention and memory, with diminished processing of negative stimuli relative to positive stimuli compared with younger adults. The current paper reviews functional magnetic resonance imaging studies investigating age-related differences in emotional processi...

  12. Taking the Concept of Citizenship in Mental Health across Countries. Reflections on Transferring Principles and Practice to Different Sociocultural Contexts

    Science.gov (United States)

    Eiroa-Orosa, Francisco José; Rowe, Michael

    2017-01-01

    Transferring principles and practices to different sociocultural and professional contexts in the field of mental health can be very complex. Previous research on public health policy points to difficulties in different areas such as the understanding the new concepts, their applicability in different health systems, and suitable approaches to its effective implementation. The purpose of this article is to describe and analyze the process of transferring the concept of Citizenship, from its United States origins in mental health outreach work with persons who are homeless to Catalonia, Spain. We define Citizenship as promoting the rights, responsibilities, roles, resources and relationships of persons with mental illnesses, along with a sense of belonging that is validated by other citizens. The process of this transition involves embedding Citizenship in the mental health “first-person” (internationally known as Consumer/Survivor/Peer) movement in Catalonia. The paper includes a discussion of the concept of transference, including a case example of the adoption of the concept of mental health recovery in different countries. Following this, we describe the United States Citizenship model and key elements of its development. We then turn to Spain and the evolution of its mental health system, and then to Catalonia for a brief case history of transference of the principles and practices of Citizenship to that region. The “take home message” of this work is that concepts being brought from one sociocultural and national context to another, must focus on contextualization in the ‘adoptee’s’ practices, including the balance between personal involvement and professional rigor, the involvement of key actors, and ongoing evaluation of actions taken. PMID:28680412

  13. Taking the Concept of Citizenship in Mental Health across Countries. Reflections on Transferring Principles and Practice to Different Sociocultural Contexts.

    Science.gov (United States)

    Eiroa-Orosa, Francisco José; Rowe, Michael

    2017-01-01

    Transferring principles and practices to different sociocultural and professional contexts in the field of mental health can be very complex. Previous research on public health policy points to difficulties in different areas such as the understanding the new concepts, their applicability in different health systems, and suitable approaches to its effective implementation. The purpose of this article is to describe and analyze the process of transferring the concept of Citizenship, from its United States origins in mental health outreach work with persons who are homeless to Catalonia, Spain. We define Citizenship as promoting the rights, responsibilities, roles, resources and relationships of persons with mental illnesses, along with a sense of belonging that is validated by other citizens. The process of this transition involves embedding Citizenship in the mental health "first-person" (internationally known as Consumer/Survivor/Peer) movement in Catalonia. The paper includes a discussion of the concept of transference, including a case example of the adoption of the concept of mental health recovery in different countries. Following this, we describe the United States Citizenship model and key elements of its development. We then turn to Spain and the evolution of its mental health system, and then to Catalonia for a brief case history of transference of the principles and practices of Citizenship to that region. The "take home message" of this work is that concepts being brought from one sociocultural and national context to another, must focus on contextualization in the 'adoptee's' practices, including the balance between personal involvement and professional rigor, the involvement of key actors, and ongoing evaluation of actions taken.

  14. Gender differences in functional hemispheric asymmetry during processing of vowels as reflected by the human brain magnetic response

    OpenAIRE

    Obleser, Jonas; Eulitz, Carsten; Lahiri, Aditi; Elbert, Thomas

    2001-01-01

    A number of findings indicate gender differences in language-related functional hemispheric brain asymmetry. To test if such gender-specific laterality is already present at the level of vowel-processing, the auditory evoked magnetic field was recorded in healthy right-handed male and female participants in response to the German synthetic vowels [a], [e] and [i]. Female participants exhibited stronger N100m responses than male participants over the left hemisphere. This observation was highl...

  15. Taking the Concept of Citizenship in Mental Health across Countries. Reflections on Transferring Principles and Practice to Different Sociocultural Contexts

    Directory of Open Access Journals (Sweden)

    Francisco José Eiroa-Orosa

    2017-06-01

    Full Text Available Transferring principles and practices to different sociocultural and professional contexts in the field of mental health can be very complex. Previous research on public health policy points to difficulties in different areas such as the understanding the new concepts, their applicability in different health systems, and suitable approaches to its effective implementation. The purpose of this article is to describe and analyze the process of transferring the concept of Citizenship, from its United States origins in mental health outreach work with persons who are homeless to Catalonia, Spain. We define Citizenship as promoting the rights, responsibilities, roles, resources and relationships of persons with mental illnesses, along with a sense of belonging that is validated by other citizens. The process of this transition involves embedding Citizenship in the mental health “first-person” (internationally known as Consumer/Survivor/Peer movement in Catalonia. The paper includes a discussion of the concept of transference, including a case example of the adoption of the concept of mental health recovery in different countries. Following this, we describe the United States Citizenship model and key elements of its development. We then turn to Spain and the evolution of its mental health system, and then to Catalonia for a brief case history of transference of the principles and practices of Citizenship to that region. The “take home message” of this work is that concepts being brought from one sociocultural and national context to another, must focus on contextualization in the ‘adoptee’s’ practices, including the balance between personal involvement and professional rigor, the involvement of key actors, and ongoing evaluation of actions taken.

  16. The Impact of Social and Cultural Difference in Relation to Job Loss and Financial Planning: Reflections on the Risk Society

    Directory of Open Access Journals (Sweden)

    David Abbott

    2006-01-01

    Full Text Available This paper is based on data collected as part of a research study which looks at how different social and cultural groups frame, and respond to, the risk of income and/or job loss. Writers like LASH, DOUGLAS and LUPTON have placed an emphasis on the importance of group membership and social categories in structuring response to different types of risk preferring to talk about "risk cultures" rather than "risk society". However, the writers acknowledge that there is little empirical research which explores this. As the first stage of our research, focus groups in two parts of the UK explored the relationship between risk and social difference with an emphasis on the risk of job or income loss. The groups were comprised of lesbian, gay and bisexual people; people from Black and Minority Ethnic backgrounds; Disabled people; and, people who actively practice a religion. Participants did not see strong links between their sexuality, race, or religion and their perceptions of, or responses to, risk. Income, and attitudinal factors were cited as being more important. Disabled people however were much more likely to make connections between being disabled and a range of barriers to responding to risky situations. URN: urn:nbn:de:0114-fqs0601160

  17. Hits to the left, flops to the right: different emotions during listening to music are reflected in cortical lateralisation patterns.

    Science.gov (United States)

    Altenmüller, Eckart; Schürmann, Kristian; Lim, Vanessa K; Parlitz, Dietrich

    2002-01-01

    In order to investigate the neurobiological mechanisms accompanying emotional valence judgements during listening to complex auditory stimuli, cortical direct current (dc)-electroencephalography (EEG) activation patterns were recorded from 16 right-handed students. Students listened to 160 short sequences taken from the repertoires of jazz, rock-pop, classical music and environmental sounds (each n=40). Emotional valence of the perceived stimuli were rated on a 5-step scale after each sequence. Brain activation patterns during listening revealed widespread bilateral fronto-temporal activation, but a highly significant lateralisation effect: positive emotional attributions were accompanied by an increase in left temporal activation, negative by a more bilateral pattern with preponderance of the right fronto-temporal cortex. Female participants demonstrated greater valence-related differences than males. No differences related to the four stimulus categories could be detected, suggesting that the actual auditory brain activation patterns were more determined by their affective emotional valence than by differences in acoustical "fine" structure. The results are consistent with a model of hemispheric specialisation concerning perceived positive or negative emotions proposed by Heilman [Journal of Neuropsychiatry and Clinical Neuroscience 9 (1997) 439].

  18. Do Individual Differences and Aging Effects in the Estimation of Geographical Slant Reflect Cognitive or Perceptual Effects?

    Directory of Open Access Journals (Sweden)

    Abigail M. Dean

    2016-07-01

    Full Text Available Several individual differences including age have been suggested to affect the perception of slant. A cross-sectional study of outdoor hill estimation (N = 106 was analyzed using individual difference measures of age, experiential knowledge, fitness, personality traits, and sex. Of particular note, it was found that for participants who reported any experiential knowledge about slant, estimates decreased (i.e., became more accurate as conscientiousness increased, suggesting that more conscientious individuals were more deliberate about taking their experiential knowledge (rather than perception into account. Effects of fitness were limited to those without experiential knowledge, suggesting that they, too, may be cognitive rather than perceptual. The observed effects of age, which tended to produce lower, more accurate estimates of hill slant, provide more evidence that older adults do not see hills as steeper. The main effect of age was to lower slant estimates; such effects may be due to implicit experiential knowledge acquired over a lifetime. The results indicate the impact of cognitive, rather than perceptual factors on individual differences in slant estimation.

  19. Experimental quantum control landscapes: Inherent monotonicity and artificial structure

    International Nuclear Information System (INIS)

    Roslund, Jonathan; Rabitz, Herschel

    2009-01-01

    Unconstrained searches over quantum control landscapes are theoretically predicted to generally exhibit trap-free monotonic behavior. This paper makes an explicit experimental demonstration of this intrinsic monotonicity for two controlled quantum systems: frequency unfiltered and filtered second-harmonic generation (SHG). For unfiltered SHG, the landscape is randomly sampled and interpolation of the data is found to be devoid of landscape traps up to the level of data noise. In the case of narrow-band-filtered SHG, trajectories are taken on the landscape to reveal a lack of traps. Although the filtered SHG landscape is trap free, it exhibits a rich local structure. A perturbation analysis around the top of these landscapes provides a basis to understand their topology. Despite the inherent trap-free nature of the landscapes, practical constraints placed on the controls can lead to the appearance of artificial structure arising from the resultant forced sampling of the landscape. This circumstance and the likely lack of knowledge about the detailed local landscape structure in most quantum control applications suggests that the a priori identification of globally successful (un)constrained curvilinear control variables may be a challenging task.

  20. Process Inherent Ultimate Safety (PIUS) reactor evaluation study: Final report

    International Nuclear Information System (INIS)

    1987-02-01

    This report presents the results of an independent study by United Engineers and Constructors (UNITED) of the SECURE-P Process Inherent Ultimate Safety (PIUS) Reactor Concept which is presently under development by the Swedish light water reactor vendor ASEA-ATOM of Vasteras, Sweden. This study was performed to investigate whether there is any realistic basis for believing that the PIUS reactor could be a viable competitor in the US energy market in the future. Assessments were limited to the technical, economic and licensing aspects of PIUS. Socio-political issues, while certainly important in answering this question, are so broad and elusive that it was considered that addressing them with the limited perspective of one small group from one company would be of questionable value and likely be misleading. Socio-political issues aside, the key issue is economics. For this reason, the specific objectives of this study were to determine if the estimated PIUS plant cost will be competitive in the US market and to identify and evaluate the technical and licensing risks that might make PIUS uneconomical or otherwise unacceptable

  1. Performance improvement CME for quality: challenges inherent to the process.

    Science.gov (United States)

    Vakani, Farhan Saeed; O'Beirne, Ronan

    2015-01-01

    The purpose of this paper is to discuss the perspective debates upon the real-time challenges for a three-staged Performance Improvement Continuing Medical Education (PI-CME) model, an innovative and potential approach for future CME, to inform providers to think, prepare and to act proactively. In this discussion, the challenges associated for adopting the American Medical Association's three-staged PI-CME model are reported. Not many institutions in USA are using a three-staged performance improvement model and then customizing it to their own healthcare context for the specific targeted audience. They integrate traditional CME methods with performance and quality initiatives, and linking with CME credits. Overall the US health system is interested in a structured PI-CME model with the potential to improve physicians practicing behaviors. Knowing the dearth of evidence for applying this structured performance improvement methodology into the design of CME activities, and the lack of clarity on challenges inherent to the process that learners and providers encounter. This paper establishes all-important first step to render the set of challenges for a three-staged PI-CME model.

  2. Conceptual design of Inherently Safe Fast Reactor (ISFR)

    International Nuclear Information System (INIS)

    Asahi, Yoshiro

    2003-01-01

    ISFR is a boiling heavy water fast reactor of process inherent ultimate safety (PIUS) type. ISFR may breed fuel in the core. Owing to a positive void coefficient, the application of the PIUS concept to ISFR is not straightforward. Thus, the gap conductance is small so that the time constant τ α of the positive void feedback process is sufficiently large, while the initially-closed two-way check valves to be used as passive switches to the pumps are installed at the lower honeycombs. As a result, the passive shutdown mechanisms can come into effect sufficiently soon to suppress the positive feedback reactivity. Both large τ α and the passive switches also help stabilize the system so that ISFR can perform a constant power operation with a simple control logic for the main coolant pump speed. In a steam generator tube rupture, fuel temperature was found to smoothly decrease to the decay heat level with nucleate boiling. The feasibility of ISFR was proved only to some extent. (author)

  3. Inherent safety features in balance-of-plant layout

    International Nuclear Information System (INIS)

    Wattelet, P.L.; Green, K.J.

    1992-01-01

    Future nuclear units must be more economical to construct and operate, and, at the same time, clearly incorporate advances in safety over the current generation of light water reactors. To achieve these goals, the root causes of safety issues must be addressed. In this way, global, cost-effective solutions can be implemented. With simple, direct design approaches, the licensing risk is minimized and configuration control is enhanced. With proper planning in the early stages of plant design, postulated accidents and events can often be mitigated by passive features inherent in the basic structure and layout, eliminating expensive added protective structures and components often found in current designs. Korea Electric Power Corporation's Yonggwang (YGN) Units 3 and 4, shown in an artist's rendering in Figure 1, are now under construction in Korea. Engineering is more than 85% complete, and Unit 3 construction is more than 50% complete. Significant steps toward design simplification and safety enhancement have been made by addressing safety concerns very early in the design effort. The tools used to achieve this were improved symmetry and separation, isolation of potential hazards, and an improved design process

  4. Demonstration of inherent safety features of HTGRs using the HTTR

    International Nuclear Information System (INIS)

    Tachibana, Yukio; Nakagawa, Shigeaki; Nakazawa, Toshio; Iyoku, Tatsuo

    2004-01-01

    Safety demonstration tests using the High Temperature Engineering Test Reactor (HTTR) are conducted for the purpose of demonstrating inherent safety features of High Temperature Gas-cooled Reactors (HTGRs) quantitatively as well as providing the core and plant transient data for validation of HTGR analysis codes for safety evaluation. The safety demonstration test are divided to the first phase and second phase tests. In the first phase tests, simulation tests of anticipated operational occurrences and anticipated transients without scram (ATWS) are conducted. The second phase tests will simulate accidents such as a depressurization accident (loss of coolant accident). The first phase test simulating reactivity insertion events and coolant flow reduction events stared in FY 2002. Post-test analyses have been conducted to reproduced the test results by using the core and plant dynamics analysis code, ACCORD and Monte Carlo code, MVP. The analysis results agreed fairly well with the test results of a control rod withdrawal test simulating reactivity insertion, and gas circulators trip test simulating coolant flow reduction, at power levels of 50% and 30% of the rated power, respectively. It is shown that improvement of the ACCORD code by taking into consideration vertical and horizontal temperature distribution gives better analysis results in the control rod withdrawal test. The fist phase safety demonstration tests will continue until FY 2005, and the second phase tests are planned to be started in FY 2006. (author)

  5. Accounting for inherent variability of growth in microbial risk assessment.

    Science.gov (United States)

    Marks, H M; Coleman, M E

    2005-04-15

    Risk assessments of pathogens need to account for the growth of small number of cells under varying conditions. In order to determine the possible risks that occur when there are small numbers of cells, stochastic models of growth are needed that would capture the distribution of the number of cells over replicate trials of the same scenario or environmental conditions. This paper provides a simple stochastic growth model, accounting only for inherent cell-growth variability, assuming constant growth kinetic parameters, for an initial, small, numbers of cells assumed to be transforming from a stationary to an exponential phase. Two, basic, microbial sets of assumptions are considered: serial, where it is assume that cells transform through a lag phase before entering the exponential phase of growth; and parallel, where it is assumed that lag and exponential phases develop in parallel. The model is based on, first determining the distribution of the time when growth commences, and then modelling the conditional distribution of the number of cells. For the latter distribution, it is found that a Weibull distribution provides a simple approximation to the conditional distribution of the relative growth, so that the model developed in this paper can be easily implemented in risk assessments using commercial software packages.

  6. Tumor inherent interferons: Impact on immune reactivity and immunotherapy.

    Science.gov (United States)

    Brockwell, Natasha K; Parker, Belinda S

    2018-04-19

    Immunotherapy has revolutionized cancer treatment, with sustained responses to immune checkpoint inhibitors reported in a number of malignancies. Such therapeutics are now being trialed in aggressive or advanced cancers that are heavily reliant on untargeted therapies, such as triple negative breast cancer. However, responses have been underwhelming to date and are very difficult to predict, leading to an inability to accurately weigh up the benefit-to-risk ratio for their implementation. The tumor immune microenvironment has been closely linked to immunotherapeutic response, with superior responses observed in patients with T cell-inflamed or 'hot' tumors. One class of cytokines, the type I interferons, are a major dictator of tumor immune infiltration and activation. Tumor cell inherent interferon signaling dramatically influences the immune microenvironment and the expression of immune checkpoint proteins, hence regulators and targets of this pathway are candidate biomarkers of immunotherapeutic response. In support of a link between IFN signaling and immunotherapeutic response, the combination of type I interferon inducers with checkpoint immunotherapy has recently been demonstrated critical for a sustained anti-tumor response in aggressive breast cancer models. Here we review evidence that links type I interferons with a hot tumor immune microenvironment, response to checkpoint inhibitors and reduced risk of metastasis that supports their use as biomarkers and therapeutics in oncology. Copyright © 2018. Published by Elsevier Ltd.

  7. Metal-fuel modeling for inherently safe reactor designs

    International Nuclear Information System (INIS)

    Miles, K.J. Jr.

    1987-01-01

    Current development of breeder reactor systems has led to the renewed interest in metal fuels. These fuels have properties that enhance the inherent safety of the system, such as high thermal conductivity, compatibility with liquid sodium, and low fuel/cladding mechanical interaction. While metal-fuel irradiation behavior is well understood, there are some areas where more information is needed to fully understand the various safety-related phenomena, such as fuel/cladding chemical interaction, eutectic melting and penetration, and axial relocation of molten fuel prior to cladding breach. Because many of these phenomena can cause changes in the reactivity state of the system, their effects on whole-core normal, anticipated, and hypothetical accident scenarios need to be studied. The metal-fuel behavior model DEFORM-5 is being developed to provide the necessary phenomenological basis for these studies. The first stage in the DEFORM-5 development has been completed. Presently, DEFORM-5 calculates the cladding strain, life fraction, and eutectic penetration thinning for Types D9, HT9, or 316 steels. This first stage of DEFORM-5 has been used to analyze the TREAT M2, M3, and M4 transients with irradiated Experimental Breeder Reactor-II driver fuel. The paper shows the DEFORM-5 and experimental results for failure times for the test pins. The results provide confidence and validation of the DEFORM-5 modeling of the cladding behavior

  8. Reflective photovoltaics

    Energy Technology Data Exchange (ETDEWEB)

    Lentine, Anthony L.; Nielson, Gregory N.; Cruz-Campa, Jose Luis; Okandan, Murat; Goeke, Ronald S.

    2018-03-06

    A photovoltaic module includes colorized reflective photovoltaic cells that act as pixels. The colorized reflective photovoltaic cells are arranged so that reflections from the photovoltaic cells or pixels visually combine into an image on the photovoltaic module. The colorized photovoltaic cell or pixel is composed of a set of 100 to 256 base color sub-pixel reflective segments or sub-pixels. The color of each pixel is determined by the combination of base color sub-pixels forming the pixel. As a result, each pixel can have a wide variety of colors using a set of base colors, which are created, from sub-pixel reflective segments having standard film thicknesses.

  9. Proton Nuclear Magnetic Resonance-Spectroscopic Discrimination of Wines Reflects Genetic Homology of Several Different Grape (V. vinifera L.) Cultivars

    Science.gov (United States)

    Zhu, Yong; Wen, Wen; Zhang, Fengmin; Hardie, Jim W.

    2015-01-01

    Background and Aims Proton nuclear magnetic resonance spectroscopy coupled multivariate analysis (1H NMR-PCA/PLS-DA) is an important tool for the discrimination of wine products. Although 1H NMR has been shown to discriminate wines of different cultivars, a grape genetic component of the discrimination has been inferred only from discrimination of cultivars of undefined genetic homology and in the presence of many confounding environmental factors. We aimed to confirm the influence of grape genotypes in the absence of those factors. Methods and Results We applied 1H NMR-PCA/PLS-DA and hierarchical cluster analysis (HCA) to wines from five, variously genetically-related grapevine (V. vinifera) cultivars; all grown similarly on the same site and vinified similarly. We also compared the semi-quantitative profiles of the discriminant metabolites of each cultivar with previously reported chemical analyses. The cultivars were clearly distinguishable and there was a general correlation between their grouping and their genetic homology as revealed by recent genomic studies. Between cultivars, the relative amounts of several of the cultivar-related discriminant metabolites conformed closely with reported chemical analyses. Conclusions Differences in grape-derived metabolites associated with genetic differences alone are a major source of 1H NMR-based discrimination of wines and 1H NMR has the capacity to discriminate between very closely related cultivars. Significance of the Study The study confirms that genetic variation among grape cultivars alone can account for the discrimination of wine by 1H NMR-PCA/PLS and indicates that 1H NMR spectra of wine of single grape cultivars may in future be used in tandem with hierarchical cluster analysis to elucidate genetic lineages and metabolomic relations of grapevine cultivars. In the absence of genetic information, for example, where predecessor varieties are no longer extant, this may be a particularly useful approach. PMID

  10. Cultural differences are reflected in variables associated with carer burden in FTD: a comparison study between India and Australia

    Science.gov (United States)

    Mekala, Shailaja; Alladi, Suvarna; Chandrasekar, Kammammettu; Fathima, Safiya; M.O.'Connor, Claire; McKinnon, Colleen; Hornberger, Michael; Piguet, Olivier; Hodges, John R.; Mioshi, Eneida

    2013-01-01

    There is great need to understand variables behind carer burden, especially in FTD. Carer burden is a complex construct, and its factors are likely to vary depending on the type of dementia, carer characteristics and cultural background. OBJECTIVE The present study aimed to compare profiles and severity of carer burden, depression, anxiety and stress in carers of FTD patients in India in comparison to Australia; to investigate which carer variables are associated with carer burden in each country. METHODS Data of 138 participants (69 dyads of carers-patients) from India and Australia (India, n=31; Australia, n=38). Carer burden was assessed with the short Zarit Burden Inventory; carer depression, anxiety and stress were measured with the Depression, Anxiety and Stress-21. Dementia severity was determined with the Frontotemporal Dementia Rating Scale (FTD-FRS), and a range of demographic variables regarding the carer and patient were also obtained. RESULTS Overall, levels of carer burden were not significantly different across India and Australia, despite more hours delivering care and higher dementia severity in India. Variables associated with burden, however, differed between countries, with carer depression, anxiety and stress strongly associated with burden in India. By contrast, depression, stress, and dementia severity were associated with burden in Australia. CONCLUSION This study demonstrated that variables associated with carer burden in FTD differ between cultures. Consequently, cultural considerations should be taken into account when planning for interventions to reduce burden. This study suggests that addressing carers' skills and coping mechanisms are likely to result in more efficacious outcomes than targeting patient symptoms alone. PMID:29213826

  11. Differences between hospitals in attainment of parathyroid hormone treatment targets in chronic kidney disease do not reflect differences in quality of care.

    Science.gov (United States)

    Peeters, Mieke J; van Zuilen, Arjan D; van den Brand, Jan A J G; Blankestijn, Peter J; ten Dam, Marc A G J; Wetzels, Jack F M

    2012-08-06

    Transparency in quality of care (QoC) is stimulated and hospitals are compared and judged on the basis of indicators of performance on specific treatment targets. In patients with chronic kidney disease, QoC differed significantly between hospitals. In this analysis we explored additional parameters to explain differences between centers in attainment of parathyroid hormone (PTH) treatment targets. Using MASTERPLAN baseline data, we selected one of the worst (center A) and one of the best (center B) performing hospitals. Differences between the two centers were analyzed from the year prior to start of the MASTERPLAN study until the baseline evaluation. Determinants of PTH were assessed. 101 patients from center A (median PTH 9.9 pmol/l, in 67 patients exceeding recommended levels) and 100 patients from center B (median PTH 6.5 pmol/l, in 34 patients exceeding recommended levels), were included. Analysis of clinical practice did not reveal differences in PTH management between the centers. Notably, hyperparathyroidism resulted in a change in therapy in less than 25% of patients. In multivariate analysis kidney transplant status, MDRD-4, and treatment center were independent predictors of PTH. However, when MDRD-6 (which accounts for serum urea and albumin) was used instead of MDRD-4, the center effect was reduced. Moreover, after calibration of the serum creatinine assays treatment center no longer influenced PTH. We show that differences in PTH control between centers are not explained by differences in treatment, but depend on incomparable patient populations and laboratory techniques. Therefore, results of hospital performance comparisons should be interpreted with great caution.

  12. Dynamics of cell proliferation and apoptosis reflect different life strategies in hydrothermal vent and cold seep vestimentiferan tubeworms.

    Science.gov (United States)

    Pflugfelder, Bettina; Cary, S Craig; Bright, Monika

    2009-07-01

    Deep-sea vestimentiferan tubeworms, which live in symbiosis with bacteria, exhibit different life strategies according to their habitat. At unstable and relatively short-lived hydrothermal vents, they grow extremely fast, whereas their close relatives at stable and long-persisting cold seeps grow slowly and live up to 300 years. Growth and age differences are thought to occur because of ecological and physiological adaptations. However, the underlying mechanisms of cell proliferation and death, which are closely linked to homeostasis, growth, and longevity, are unknown. Here, we show by immunohistochemical and ultrastructural cell cycle analyses that cell proliferation activities of the two species studied are higher than in any other characterized invertebrate, being only comparable with tumor and wound-healing processes. The slow growth in Lamellibrachia luymesi from cold seeps results from balanced activities of proliferation and apoptosis in the epidermis. In contrast, Riftia pachyptila from hydrothermal vents grows fast because apoptosis is down-regulated in this tissue. The symbiont-housing organ, the trophosome, exhibits a complex cell cycle and terminal differentiation pattern in both species, and growth is regulated by proliferation. These mechanisms have similarities to the up- and down-regulation of proliferation or apoptosis in various types of tumor, although they occur in healthy animals in this study, thus providing significant insights into the underlying mechanisms of growth and longevity.

  13. Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells

    Directory of Open Access Journals (Sweden)

    Monticone Massimiliano

    2012-08-01

    Full Text Available Abstract Background Most patients affected by Glioblastoma multiforme (GBM, grade IV glioma experience a recurrence of the disease because of the spreading of tumor cells beyond surgical boundaries. Unveiling mechanisms causing this process is a logic goal to impair the killing capacity of GBM cells by molecular targeting. We noticed that our long-term GBM cultures, established from different patients, may display two categories/types of growth behavior in an orthotopic xenograft model: expansion of the tumor mass and formation of tumor branches/nodules (nodular like, NL-type or highly diffuse single tumor cell infiltration (HD-type. Methods We determined by DNA microarrays the gene expression profiles of three NL-type and three HD-type long-term GBM cultures. Subsequently, individual genes with different expression levels between the two groups were identified using Significance Analysis of Microarrays (SAM. Real time RT-PCR, immunofluorescence and immunoblot analyses, were performed for a selected subgroup of regulated gene products to confirm the results obtained by the expression analysis. Results Here, we report the identification of a set of 34 differentially expressed genes in the two types of GBM cultures. Twenty-three of these genes encode for proteins localized to the plasma membrane and 9 of these for proteins are involved in the process of cell adhesion. Conclusions This study suggests the participation in the diffuse infiltrative/invasive process of GBM cells within the CNS of a novel set of genes coding for membrane-associated proteins, which should be thus susceptible to an inhibition strategy by specific targeting. Massimiliano Monticone and Antonio Daga contributed equally to this work

  14. Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells.

    Science.gov (United States)

    Monticone, Massimiliano; Daga, Antonio; Candiani, Simona; Romeo, Francesco; Mirisola, Valentina; Viaggi, Silvia; Melloni, Ilaria; Pedemonte, Simona; Zona, Gianluigi; Giaretti, Walter; Pfeffer, Ulrich; Castagnola, Patrizio

    2012-08-17

    Most patients affected by Glioblastoma multiforme (GBM, grade IV glioma) experience a recurrence of the disease because of the spreading of tumor cells beyond surgical boundaries. Unveiling mechanisms causing this process is a logic goal to impair the killing capacity of GBM cells by molecular targeting.We noticed that our long-term GBM cultures, established from different patients, may display two categories/types of growth behavior in an orthotopic xenograft model: expansion of the tumor mass and formation of tumor branches/nodules (nodular like, NL-type) or highly diffuse single tumor cell infiltration (HD-type). We determined by DNA microarrays the gene expression profiles of three NL-type and three HD-type long-term GBM cultures. Subsequently, individual genes with different expression levels between the two groups were identified using Significance Analysis of Microarrays (SAM). Real time RT-PCR, immunofluorescence and immunoblot analyses, were performed for a selected subgroup of regulated gene products to confirm the results obtained by the expression analysis. Here, we report the identification of a set of 34 differentially expressed genes in the two types of GBM cultures. Twenty-three of these genes encode for proteins localized to the plasma membrane and 9 of these for proteins are involved in the process of cell adhesion. This study suggests the participation in the diffuse infiltrative/invasive process of GBM cells within the CNS of a novel set of genes coding for membrane-associated proteins, which should be thus susceptible to an inhibition strategy by specific targeting.Massimiliano Monticone and Antonio Daga contributed equally to this work.

  15. Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells

    International Nuclear Information System (INIS)

    Monticone, Massimiliano; Giaretti, Walter; Pfeffer, Ulrich; Daga, Antonio; Candiani, Simona; Romeo, Francesco; Mirisola, Valentina; Viaggi, Silvia; Melloni, Ilaria; Pedemonte, Simona; Zona, Gianluigi

    2012-01-01

    Most patients affected by Glioblastoma multiforme (GBM, grade IV glioma) experience a recurrence of the disease because of the spreading of tumor cells beyond surgical boundaries. Unveiling mechanisms causing this process is a logic goal to impair the killing capacity of GBM cells by molecular targeting. We noticed that our long-term GBM cultures, established from different patients, may display two categories/types of growth behavior in an orthotopic xenograft model: expansion of the tumor mass and formation of tumor branches/nodules (nodular like, NL-type) or highly diffuse single tumor cell infiltration (HD-type). We determined by DNA microarrays the gene expression profiles of three NL-type and three HD-type long-term GBM cultures. Subsequently, individual genes with different expression levels between the two groups were identified using Significance Analysis of Microarrays (SAM). Real time RT-PCR, immunofluorescence and immunoblot analyses, were performed for a selected subgroup of regulated gene products to confirm the results obtained by the expression analysis. Here, we report the identification of a set of 34 differentially expressed genes in the two types of GBM cultures. Twenty-three of these genes encode for proteins localized to the plasma membrane and 9 of these for proteins are involved in the process of cell adhesion. This study suggests the participation in the diffuse infiltrative/invasive process of GBM cells within the CNS of a novel set of genes coding for membrane-associated proteins, which should be thus susceptible to an inhibition strategy by specific targeting. Massimiliano Monticone and Antonio Daga contributed equally to this work

  16. Thermally responsive polymer electrolytes for inherently safe electrochemical energy storage

    Science.gov (United States)

    Kelly, Jesse C.

    Electrochemical double layer capacitors (EDLCs), supercapacitors and Li-ion batteries have emerged as premier candidates to meet the rising demands in energy storage; however, such systems are limited by thermal hazards, thermal runaway, fires and explosions, all of which become increasingly more dangerous in large-format devices. To prevent such scenarios, thermally-responsive polymer electrolytes (RPEs) that alter properties in electrochemical energy storage devices were designed and tested. These RPEs will be used to limit or halt device operation when temperatures increase beyond a predetermined threshold, therefore limiting further heating. The development of these responsive systems will offer an inherent safety mechanism in electrochemical energy storage devices, while preserving the performance, lifetimes, and versatility that large-format systems require. Initial work focused on the development of a model system that demonstrated the concept of RPEs in an electrochemical device. Aqueous electrolyte solutions of polymers exhibiting properties that change in response to temperature were developed for applications in EDLCs and supercapacitors. These "smart materials" provide a means to control electrochemical systems where polymer phase separation at high temperatures affects electrolyte properties and inhibits device performance. Aqueous RPEs were synthesized using N-isopropylacrylamide, which governs the thermal properties, and fractions of acrylic acid or vinyl sulfonic acids, which provide ions to the solution. The molecular properties of these aqueous RPEs, specifically the ionic composition, were shown to influence the temperature-dependent electrolyte properties and the extent to which these electrolytes control the energy storage characteristics of a supercapacitor device. Materials with high ionic content provided the highest room temperature conductivity and electrochemical activity; however, RPEs with low ionic content provided the highest "on

  17. Carbon isotopes of dissolved inorganic carbon reflect utilization of different carbon sources by microbial communities in two limestone aquifer assemblages

    Directory of Open Access Journals (Sweden)

    M. E. Nowak

    2017-08-01

    Full Text Available Isotopes of dissolved inorganic carbon (DIC are used to indicate both transit times and biogeochemical evolution of groundwaters. These signals can be complicated in carbonate aquifers, as both abiotic (i.e., carbonate equilibria and biotic factors influence the δ13C and 14C of DIC. We applied a novel graphical method for tracking changes in the δ13C and 14C of DIC in two distinct aquifer complexes identified in the Hainich Critical Zone Exploratory (CZE, a platform to study how water transport links surface and shallow groundwaters in limestone and marlstone rocks in central Germany. For more quantitative estimates of contributions of different biotic and abiotic carbon sources to the DIC pool, we used the NETPATH geochemical modeling program, which accounts for changes in dissolved ions in addition to C isotopes. Although water residence times in the Hainich CZE aquifers based on hydrogeology are relatively short (years or less, DIC isotopes in the shallow, mostly anoxic, aquifer assemblage (HTU were depleted in 14C compared to a deeper, oxic, aquifer complex (HTL. Carbon isotopes and chemical changes in the deeper HTL wells could be explained by interaction of recharge waters equilibrated with post-bomb 14C sources with carbonates. However, oxygen depletion and δ13C and 14C values of DIC below those expected from the processes of carbonate equilibrium alone indicate considerably different biogeochemical evolution of waters in the upper aquifer assemblage (HTU wells. Changes in 14C and 13C in the upper aquifer complexes result from a number of biotic and abiotic processes, including oxidation of 14C-depleted OM derived from recycled microbial carbon and sedimentary organic matter as well as water–rock interactions. The microbial pathways inferred from DIC isotope shifts and changes in water chemistry in the HTU wells were supported by comparison with in situ microbial community structure based on 16S rRNA analyses. Our findings

  18. An inherently parallel method for solving discretized diffusion equations

    International Nuclear Information System (INIS)

    Eccleston, B.R.; Palmer, T.S.

    1999-01-01

    A Monte Carlo approach to solving linear systems of equations is being investigated in the context of the solution of discretized diffusion equations. While the technique was originally devised decades ago, changes in computer architectures (namely, massively parallel machines) have driven the authors to revisit this technique. There are a number of potential advantages to this approach: (1) Analog Monte Carlo techniques are inherently parallel; this is not necessarily true to today's more advanced linear equation solvers (multigrid, conjugate gradient, etc.); (2) Some forms of this technique are adaptive in that they allow the user to specify locations in the problem where resolution is of particular importance and to concentrate the work at those locations; and (3) These techniques permit the solution of very large systems of equations in that matrix elements need not be stored. The user could trade calculational speed for storage if elements of the matrix are calculated on the fly. The goal of this study is to compare the parallel performance of Monte Carlo linear solvers to that of a more traditional parallelized linear solver. The authors observe the linear speedup that they expect from the Monte Carlo algorithm, given that there is no domain decomposition to cause significant communication overhead. Overall, PETSc outperforms the Monte Carlo solver for the test problem. The PETSc parallel performance improves with larger numbers of unknowns for a given number of processors. Parallel performance of the Monte Carlo technique is independent of the size of the matrix and the number of processes. They are investigating modifications to the scheme to accommodate matrix problems with positive off-diagonal elements. They are also currently coding an on-the-fly version of the algorithm to investigate the solution of very large linear systems

  19. Plant-based assessment of inherent soil productivity and contributions to China's cereal crop yield increase since 1980.

    Directory of Open Access Journals (Sweden)

    Mingsheng Fan

    Full Text Available OBJECTIVE: China's food production has increased 6-fold during the past half-century, thanks to increased yields resulting from the management intensification, accomplished through greater inputs of fertilizer, water, new crop strains, and other Green Revolution's technologies. Yet, changes in underlying quality of soils and their effects on yield increase remain to be determined. Here, we provide a first attempt to quantify historical changes in inherent soil productivity and their contributions to the increase in yield. METHODS: The assessment was conducted based on data-set derived from 7410 on-farm trials, 8 long-term experiments and an inventory of soil organic matter concentrations of arable land. RESULTS: Results show that even without organic and inorganic fertilizer addition crop yield from on-farm trials conducted in the 2000s was significantly higher compared with those in the 1980s - the increase ranged from 0.73 to 1.76 Mg/ha for China's major irrigated cereal-based cropping systems. The increase in on-farm yield in control plot since 1980s was due primarily to the enhancement of soil-related factors, and reflected inherent soil productivity improvement. The latter led to higher and stable yield with adoption of improved management practices, and contributed 43% to the increase in yield for wheat and 22% for maize in the north China, and, 31%, 35% and 22% for early and late rice in south China and for single rice crop in the Yangtze River Basin since 1980. CONCLUSIONS: Thus, without an improvement in inherent soil productivity, the 'Agricultural Miracle in China' would not have happened. A comprehensive strategy of inherent soil productivity improvement in China, accomplished through combining engineering-based measures with biological-approaches, may be an important lesson for the developing world. We propose that advancing food security in 21st century for both China and other parts of world will depend on continuously improving

  20. Variations of vessel diameter and δ13C in false rings of Arbutus unedo L. reflect different environmental conditions.

    Science.gov (United States)

    Battipaglia, Giovanna; De Micco, Veronica; Brand, Willi A; Linke, Petra; Aronne, Giovanna; Saurer, Matthias; Cherubini, Paolo

    2010-12-01

    Woody species in Mediterranean ecosystems form intra-annual density fluctuations (IADFs) in tree rings in response to changes in environmental conditions, especially water availability. Dendrochronology, quantitative wood anatomy and high-resolution isotopic analysis (using a laser ablation technique) were used to characterize IADFs in Arbutus unedo shrubs grown on two sites with different water availability on the island of Elba (Italy). Our findings show that IADF characterization can provide information about the relationship between environmental factors and tree growth at the seasonal level. At the more xeric site, IADFs mainly located in the early and middle parts of the annual ring, showed a decrease in vessel size and an increase in δ(13) C as a result of drought deficit. Opposite trends were found at the more mesic site, with IADFs located at the end of the ring and associated with a lower δ(13) C. Moreover, at the first site, IADFs are induced by drought deficit, while at the second site IADFs are linked with the regrowth in the last part of the growing season triggered by favourable wet conditions. This combined approach is a promising way for dating problematic wood samples and interpreting the phenomena that trigger the formation of IADFs in the Mediterranean environment. © The Authors (2010). Journal compilation © New Phytologist Trust (2010).

  1. Age Differences in Brain Activity during Emotion Processing: Reflections of Age-Related Decline or Increased Emotion Regulation?

    Science.gov (United States)

    Nashiro, Kaoru; Sakaki, Michiko; Mather, Mara

    2012-01-01

    Despite the fact that physical health and cognitive abilities decline with aging, the ability to regulate emotion remains stable and in some aspects improves across the adult life span. Older adults also show a positivity effect in their attention and memory, with diminished processing of negative stimuli relative to positive stimuli compared with younger adults. The current paper reviews functional magnetic resonance imaging studies investigating age-related differences in emotional processing and discusses how this evidence relates to two opposing theoretical accounts of older adults’ positivity effect. The aging-brain model [Cacioppo et al. in: Social Neuroscience: Toward Understanding the Underpinnings of the Social Mind. New York, Oxford University Press, 2011] proposes that older adults’ positivity effect is a consequence of age-related decline in the amygdala, whereas the cognitive control hypothesis [Kryla-Lighthall and Mather in: Handbook of Theories of Aging, ed 2. New York, Springer, 2009; Mather and Carstensen: Trends Cogn Sci 2005;9:496–502; Mather and Knight: Psychol Aging 2005;20:554–570] argues that the positivity effect is a result of older adults’ greater focus on regulating emotion. Based on evidence for structural and functional preservation of the amygdala in older adults and findings that older adults show greater prefrontal cortex activity than younger adults while engaging in emotion-processing tasks, we argue that the cognitive control hypothesis is a more likely explanation for older adults’ positivity effect than the aging-brain model. PMID:21691052

  2. Inherent Reward and Risk (Part I): Towards a Universal Paradigm for Investment Analysis

    OpenAIRE

    Liang Zou

    2000-01-01

    In this paper, a new paradigm is developed for analyzinginvestment strategies and pricing financial assets. This paradigmassumes that any investment strategy has its own “inherent reward”and “inherent risk” that can be judged with common sense. Ijustify axiomatically the existence and uniqueness (ratio scale)of inherent reward (U) and inherent risk (D) that could beregarded as universal measures of reward and risk for any giveninvestment strategy. Incorporating the notion of “inherentefficien...

  3. Attaining the canopy in dry and moist tropical forests: strong differences in tree growth trajectories reflect variation in growing conditions.

    Science.gov (United States)

    Brienen, Roel J W; Zuidema, Pieter A; Martínez-Ramos, Miguel

    2010-06-01

    Availability of light and water differs between tropical moist and dry forests, with typically higher understorey light levels and lower water availability in the latter. Therefore, growth trajectories of juvenile trees--those that have not attained the canopy--are likely governed by temporal fluctuations in light availability in moist forests (suppressions and releases), and by spatial heterogeneity in water availability in dry forests. In this study, we compared juvenile growth trajectories of Cedrela odorata in a dry (Mexico) and a moist forest (Bolivia) using tree rings. We tested the following specific hypotheses: (1) moist forest juveniles show more and longer suppressions, and more and stronger releases; (2) moist forest juveniles exhibit wider variation in canopy accession pattern, i.e. the typical growth trajectory to the canopy; (3) growth variation among dry forest juveniles persists over longer time due to spatial heterogeneity in water availability. As expected, the proportion of suppressed juveniles was higher in moist than in dry forest (72 vs. 17%). Moist forest suppressions also lasted longer (9 vs. 5 years). The proportion of juveniles that experienced releases in moist forest (76%) was higher than in dry forest (41%), and releases in moist forests were much stronger. Trees in the moist forest also had a wider variation in canopy accession patterns compared to the dry forest. Our results also showed that growth variation among juvenile trees persisted over substantially longer periods of time in dry forest (>64 years) compared to moist forest (12 years), most probably because of larger persistent spatial variation in water availability. Our results suggest that periodic increases in light availability are more important for attaining the canopy in moist forests, and that spatial heterogeneity in water availability governs long-term tree growth in dry forests.

  4. Anomalous baroreflex functionality inherent in floxed and Cre-Lox mice: an overlooked physiological phenotype.

    Science.gov (United States)

    Tsai, Ching-Yi; Poon, Yan-Yuen; Chen, Chang-Han; Chan, Samuel H H

    2017-10-01

    The last two decades have seen the emergence of Cre-Lox recombination as one of the most powerful and versatile technologies for cell-specific genetic engineering of mammalian cells. Understandably, the primary concerns in the practice of Cre-Lox recombination are whether the predicted genome has been correctly modified and the targeted phenotypes expressed. Rarely are the physiological conditions of the animals routinely examined because the general assumption is that they are normal. Based on corroborative results from radiotelemetric recording, power spectral analysis, and magnetic resonance imaging/diffusion tensor imaging in brain-derived neurotrophic factor-floxed mice, the present study revealed that this assumption requires amendment. We found that despite comparable blood pressure and heart rate with C57BL/6 or Cre mice under the conscious state, floxed and Cre-Lox mice exhibited diminished baroreflex-mediated sympathetic vasomotor tone and cardiac vagal baroreflex. We further found that the capacity and plasticity of baroreflex of these two strains of mice under isoflurane anesthesia were retarded, as reflected by reduced connectivity between the nucleus tractus solitarii and rostral ventrolateral medulla or nucleus ambiguus. The identification of anomalous baroreflex functionality inherent in floxed and Cre-Lox mice points to the importance of incorporating physiological phenotypes into studies that engage gene manipulations such as Cre-Lox recombination. NEW & NOTEWORTHY We established that anomalous baroreflex functionality is inherent in floxed and Cre-Lox mice. These two mouse strains exhibited diminished baroreflex-mediated sympathetic vasomotor tone and cardiac vagal baroreflex under the conscious state, retarded capacity and plasticity of baroreflex under isoflurane anesthesia, and reduced connectivity between key nuclei in the baroreflex neural circuits. Copyright © 2017 the American Physiological Society.

  5. Chemical looping combustion. Fuel conversion with inherent CO2 capture

    Energy Technology Data Exchange (ETDEWEB)

    Brandvoll, Oeyvind

    2005-07-01

    ONiAl do not rule out CLC as a viable alternative for CO2 capture, but long term durability studies along with realistic testing of the carrier in a continuous rig is needed to firmly conclude. For comparative purposes a perovskite was synthesized and tested in CLC, under similar conditions as NiONiAl. The results indicate that in a moving bed CLC application, perovskites have inherent disadvantages as compared to simpler compounds, by virtue of low relative oxygen content. (Author)

  6. Mitigation of Severe Accident Consequences Using Inherent Safety Principles

    International Nuclear Information System (INIS)

    Wigeland, R.A.; Cahalan, J.E.

    2009-01-01

    Sodium-cooled fast reactors are designed to have a high level of safety. Events of high probability of occurrence are typically handled without consequence through reliable engineering systems and good design practices. For accidents of lower probability, the initiating events are characterized by larger and more numerous challenges to the reactor system, such as failure of one or more major engineered systems and can also include a failure to scram the reactor in response. As the initiating conditions become more severe, they have the potential for creating serious consequences of potential safety significance, including fuel melting, fuel pin disruption and recriticality. If the progression of such accidents is not mitigated by design features of the reactor, energetic events and dispersal of radioactive materials may result. For severe accidents, there are several approaches that can be used to mitigate the consequences of such severe accident initiators, which typically include fuel pin failures and core disruption. One approach is to increase the reliability of the reactor protection system so that the probability of an ATWS event is reduced to less than 1 x 10-6 per reactor year, where larger accident consequences are allowed, meeting the U.S. NRC goal of relegating such accident consequences as core disruption to these extremely low probabilities. The main difficulty with this approach is to convincingly test and guarantee such increased reliability. Another approach is to increase the redundancy of the reactor scram system, which can also reduce the probability of an ATWS event to a frequency of less than 1 x 10-6 per reactor year or lower. The issues with this approach are more related to reactor core design, with the need for a greater number of control rod positions in the reactor core and the associated increase in complexity of the reactor protection system. A third approach is to use the inherent reactivity feedback that occurs in a fast reactor to

  7. Technology which led to the westinghouse inherently safe liquid metal reactor

    International Nuclear Information System (INIS)

    Schmidt, J.E.; Coffield, R.D.; Doncals, R.A.; Kalinowski, J.E.; Markley, R.A.

    1985-01-01

    The Fast Flux Test Facility (FFTF) and the Clinch River Breeder Reactor programs resulted in an understanding of liquid metal reactor behavior that is being used to design inherent safety capability into liquid metal reactors. Technological advances give the same beneficial operating characteristics of conventional liquid metal reactors, however, the addition of inherently safe design features precludes the initiation of hypothetical core disruptive accidents. These innovative features permit inherent safety capability to be demonstrated with more than adequate margins. Also, the variety of inherent safety features provides the designers with options in selecting inherent design features for a specific reactor application

  8. Are autobiographical memories inherently social? Evidence from an fMRI study.

    Directory of Open Access Journals (Sweden)

    Linda Wilbers

    Full Text Available The story of our lifetime - our narrative self - is constructed from our autobiographical memories. A central claim of social psychology is that this narrative self is inherently social: When we construct our lives, we do so in a real or imagined interaction. This predicts that self-referential processes which are involved in recall of autobiographical memories overlap with processes involved in social interactions. Indeed, previous functional MRI studies indicate that regions in the medial prefrontal cortex (mPFC are activated during autobiographical memory recall and virtual communication. However, no fMRI study has investigated recall of autobiographical memories in a real-life interaction. We developed a novel paradigm in which participants overtly reported self-related and other-related memories to an experimenter, whose non-verbal reactions were being filmed and online displayed to the participants in the scanner. We found that recall of autobiographical vs. non-autobiographical memories was associated with activation of the mPFC, as was recall in the social as compared to a non-social control condition; however, both contrasts involved different non-overlapping regions within the mPFC. These results indicate that self-referential processes involved in autobiographical memory recall are different from processes supporting social interactions, and argue against the hypothesis that autobiographical memories are inherently social.

  9. Indispensable role of biochar-inherent mineral constituents in its environmental applications: A review.

    Science.gov (United States)

    Xu, Xiaoyun; Zhao, Yinghao; Sima, Jingke; Zhao, Ling; Mašek, Ondřej; Cao, Xinde

    2017-10-01

    Biochar typically consists of both carbon and mineral fractions, and the carbon fraction has been generally considered to determine its properties and applications. Recently, an increasing body of research has demonstrated that mineral components inherent in biochar, such as alkali or alkaline earth metals in the form of carbonates, phosphates, or oxides, could also influence the properties and thus the applications. The review articles published thus far have mainly focused on multiple environmental and agronomic applications of biochar, including carbon sequestration, soil improvement, environmental remediation, etc. This review aims to highlight the indispensable role of the mineral fraction of biochar in these different applications, especially in environmental applications. Specifically, it provides a critical review of current research findings related to the mineral composition of biochar and the effect of the mineral fraction on the physicochemical properties, contaminant sorption, carbon retention and stability, and nutrient bioavailability of biochar. Furthermore, the role of minerals in the emerging applications of biochar, as a precursor for fuel cells, supercapacitors, and photoactive components, is also summarized. Overall, inherent minerals should be fully considered while determining the most appropriate application for any given biochar. A thorough understanding of the role of biochar-bound minerals in different applications will also allow the design or selection of the most suitable biochar for specific applications based on the consideration of feedstock composition, production parameters, and post-treatment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Personal Reflections

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Personal Reflections. Articles in Resonance – Journal of Science Education. Volume 6 Issue 3 March 2001 pp 90-93 Personal Reflections. Why did I opt for Career in Science? Jayant V Narlikar · More Details Fulltext PDF. Volume 9 Issue 8 August 2004 pp 89-89 ...

  11. Reflection groups

    International Nuclear Information System (INIS)

    Eggermont, G.

    2006-01-01

    In 2005, PISA organised proactive meetings of reflection groups on involvement in decision making, expert culture and ethical aspects of radiation protection.All reflection group meetings address particular targeted audiences while the output publication in book form is put forward

  12. Reflection ciphers

    DEFF Research Database (Denmark)

    Boura, Christina; Canteaut, Anne; Knudsen, Lars Ramkilde

    2017-01-01

    study the necessary properties for this coupling permutation. Special care has to be taken of some related-key distinguishers since, in the context of reflection ciphers, they may provide attacks in the single-key setting.We then derive some criteria for constructing secure reflection ciphers...

  13. Quantifying Reflection

    DEFF Research Database (Denmark)

    Alcock, Gordon Lindsay

    2013-01-01

    ´ These are all based on Blooms taxonomy and levels of competence and form a major part of individual student and group learning portfolios. Key Words :Project-Based learning, Reflective Portfolios, Self assessment, Defining learning gains, Developing learning strategies , Reflections on and for learning....... It contrasts the students’ self-assessment in a range of ‘product’ skills such as Revit, Structural Design, Mathematics of construction, Technical Installations; as well as ‘process’ competencies such as ‘Working in a team’, Sharing knowledge, Maintaining a portfolio and Reflecting ON learning and FOR learning......This paper documents 1st semester student reflections on “learning to learn” in a team-based PBL environment with quantitative and qualitative student reflective feedback on the learning gains of 60 Architectural Technology and Construction Management students at VIA University College, Denmark...

  14. Diffuse reflectance infrared Fourier-Transform spectra of selected organic compounds

    Energy Technology Data Exchange (ETDEWEB)

    Harmon, S.H.; Caton, J.E.

    1982-05-01

    Diffuse reflectance infrared spectra of a variety of different organic compounds have been determined. Profiles of the spectra along with the location and relative intensity of the principal bands have been included for each compound studied. In addition both diffuse reflectance and transmittance infrared spectra were obtained for the same samples, and the spectral results were compared. Although some minor variations are observed between a diffuse reflectance spectrum and the corresponding transmittance spectrum, the diffuse reflectance is quite useful and may be a superior technique for the study of many samples because it possesses an inherently higher signal-to-noise response, requires less sample preparation and allows a very wide range of samples (solids, liquids of low volatility, neat sample, or sample diluted in a reflecting medium) to be studied under very similar conditions.

  15. Real-time detection of dielectric anisotropy or isotropy in unconventional oil-gas reservoir rocks supported by the oblique-incidence reflectivity difference technique.

    Science.gov (United States)

    Zhan, Honglei; Wang, Jin; Zhao, Kun; Lű, Huibin; Jin, Kuijuan; He, Liping; Yang, Guozhen; Xiao, Lizhi

    2016-12-15

    Current geological extraction theory and techniques are very limited to adequately characterize the unconventional oil-gas reservoirs because of the considerable complexity of the geological structures. Optical measurement has the advantages of non-interference with the earth magnetic fields, and is often useful in detecting various physical properties. One key parameter that can be detected using optical methods is the dielectric permittivity, which reflects the mineral and organic properties. Here we reported an oblique-incidence reflectivity difference (OIRD) technique that is sensitive to the dielectric and surface properties and can be applied to characterization of reservoir rocks, such as shale and sandstone core samples extracted from subsurface. The layered distribution of the dielectric properties in shales and the uniform distribution in sandstones are clearly identified using the OIRD signals. In shales, the micro-cracks and particle orientation result in directional changes of the dielectric and surface properties, and thus, the isotropy and anisotropy of the rock can be characterized by OIRD. As the dielectric and surface properties are closely related to the hydrocarbon-bearing features in oil-gas reservoirs, we believe that the precise measurement carried with OIRD can help in improving the recovery efficiency in well-drilling process.

  16. Ulcerative colitis, Crohn's disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn's disease.

    Directory of Open Access Journals (Sweden)

    Joachim Høg Mortensen

    Full Text Available Increased protease activity is a key pathological feature of inflammatory bowel disease (IBD. However, the differences in extracellular matrix remodelling (ECM in Crohn's disease (CD and ulcerative colitis (UC are not well described. An increased understanding of the inflammatory processes may provide optimized disease monitoring and diagnostics. We investigated the tissue remodelling in IBD and IBS patients by using novel blood-based biomarkers reflecting ECM remodelling.Five ECM biomarkers (VICM, BGM, EL-NE, C5M, Pro-C5 were measured by competitive ELISAs in serum from 72 CD patients, 60 UC patients, 22 patients with irritable bowel syndrome (IBS, and 24 healthy donors. One-way analysis of variance, Mann-Whitney U-test, logistic regression models, and receiver operator characteristics (ROC curve analysis was carried out to evaluate the diagnostic accuracy of the biomarkers.The ECM remodelling was significantly different in UC compared to CD. The best biomarker combination to differentiate UC from CD and colonic CD was BGM and VICM (AUC = 0.98, P5mg/mL, correlation of Pro-C5 (r = 0.36 with CDAI was slightly improved compared to CRP (r = 0.27 corrected for the use of immunosuppressant. Furthermore, BGM and EL-NE biomarkers were highly associated with colon inflammation in CD patients.ECM fragments of tissue remodelling in IBD affect UC and CD differently, and may aid in differentiating IBD from IBS (EL-NE, BGM, Pro-C5, and UC from CD patients (BGM, VICM. Formation of type V collagen is related to the level of inflammation in CD and may reflect disease activity in CD.

  17. Worldwide advanced nuclear power reactors with passive and inherent safety: What, why, how, and who

    International Nuclear Information System (INIS)

    Forsberg, C.W.; Reich, W.J.

    1991-09-01

    The political controversy over nuclear power, the accidents at Three Mile Island (TMI) and Chernobyl, international competition, concerns about the carbon dioxide greenhouse effect and technical breakthroughs have resulted in a segment of the nuclear industry examining power reactor concepts with PRIME safety characteristics. PRIME is an acronym for Passive safety, Resilience, Inherent safety, Malevolence resistance, and Extended time after initiation of an accident for external help. The basic ideal of PRIME is to develop power reactors in which operator error, internal sabotage, or external assault do not cause a significant release of radioactivity to the environment. Several PRIME reactor concepts are being considered. In each case, an existing, proven power reactor technology is combined with radical innovations in selected plant components and in the safety philosophy. The Process Inherent Ultimate Safety (PIUS) reactor is a modified pressurized-water reactor, the Modular High Temperature Gas-Cooled Reactor (MHTGR) is a modified gas-cooled reactor, and the Advanced CANDU Project is a modified heavy-water reactor. In addition to the reactor concepts, there is parallel work on super containments. The objective is the development of a passive ''box'' that can contain radioactivity in the event of any type of accident. This report briefly examines: why a segment of the nuclear power community is taking this new direction, how it differs from earlier directions, and what technical options are being considered. A more detailed description of which countries and reactor vendors have undertaken activities follows. 41 refs

  18. Inherent Immunogenicity or Lack Thereof of Pluripotent Stem Cells: Implications for Cell Replacement Therapy

    Directory of Open Access Journals (Sweden)

    Arvind Chhabra

    2017-08-01

    Full Text Available Donor-specific induced pluripotent stem cells (iPSCs offer opportunities for personalized cell replacement therapeutic approaches due to their unlimited self-renewal potential and ability to differentiate into different somatic cells. A significant progress has been made toward generating iPSC lines that are free of integrating viral vectors, development of xeno-free culture conditions, and differentiation of pluripotent stem cells (PSCs into functional somatic cell lineages. Since donor-specific iPSC lines are genetically identical to the individual, they are expected to be immunologically matched and these iPSC lines and their cellular derivatives are not expected to be immunologically rejected. However, studies in mouse models, utilizing rejection of teratomas as a model, have claimed that syngenic iPSC lines, especially the iPSC lines derived with integrating viral vectors, could be inherently immunogenic. This manuscript reviews current understanding of inherent immunogenicity of PSC lines, especially that of the human iPSC lines and their cellular derivatives, and strategies to overcome it.

  19. Problems in the assessment of inherent safety characteristics of nuclear reactors

    International Nuclear Information System (INIS)

    Garribba, S.F.; Vivante, C.

    1988-01-01

    A number of proposals are being made for an increased RD and D effort on advanced nuclear power reactors that would display outstanding safety performance. A common characteristic of the different reactor concepts would be their limited reliance upon active engineered systems under major accident conditions. However, when submitted to a more close scrutiny reactor concept options may reveal diverging safety behaviors and also development opportunities. In this respect, three issues are explored in this paper. A first question is the meaning of non-active, i.e. inherent and passive safety features. Next, is the ranking of advanced and new reactor concepts from the viewpoint of inherent and passive safety. Multiple correspondence analysis may provide a simple tool, whose use is shown for the case of HTR-500, AP600 and PRISM. Conversely, probabilistic risk assessment would allow quantitative comparisons, although lack of information and data is an obstacle. Finally, is demonstration of safety performances as a step toward market deployment of the new reactor systems

  20. Dealing with uncertainty and pursuing superior technology options in risk management-The inherency risk analysis

    International Nuclear Information System (INIS)

    Helland, Aasgeir

    2009-01-01

    Current regulatory systems focus on the state of scientific evidence as the predominant factor for how to handle risks to human health and the environment. However, production and assessment of risk information are costly and time-consuming, and firms have an intrinsic disincentive to produce and distribute information about risks of their products as this could endanger their production opportunities and sales. An emphasis on more or better science may result in insufficient thought and attention going into the exploration of technology alternatives, and that risk management policies miss out on the possible achievement of a more favorable set of consequences. In this article, a method is proposed that combines risk assessment with the search for alternative technological options as a part of the risk management procedure. The method proposed is the inherency risk analysis where the first stage focuses on the original agent subject to investigation, the second stage focuses on identifying technological options whereas the third stage reviews the different alternatives, searching for the most attractive tradeoffs between costs and inherent safety. This is then used as a fundament for deciding which technology option to pursue. This method aims at providing a solution-focused, systematic technology-based approach for addressing and setting priorities for environmental problems. By combining risk assessment with a structured approach to identify superior technology options within a risk management system, the result could very well be a win-win situation for both company and the environment.

  1. Effect of reflective practice education on self-reflection, insight, and reflective thinking among experienced nurses: a pilot study.

    Science.gov (United States)

    Asselin, Marilyn E; Fain, James A

    2013-01-01

    A mixed-method study was conducted to determine whether nurses' participation in a reflective practice continuing education program using a structured reflection model makes a difference in nurses' self-reflection, insight, and reflective thinking about clinical practice situations. Findings suggested that use of structured reflection using question cues, written narratives, and peer-facilitated reflection increased nurses' engagement in self-reflection and enhanced reflective thinking in practice. Including reflective practice education in novice orientation and preceptor training may be beneficial.

  2. Label-Free and Real-Time Monitor of Binding and Dissociation Processes between Protein A and Swine IgG by Oblique-Incidence Reflectivity Difference Method

    International Nuclear Information System (INIS)

    He Li-Ping; Liu Shuang; Dai Jun; Lu Hui-Bin; Jin Kui-Juan; Yang Guo-Zhen; Wu Lin; Liu Guo-Zhen; Wei Han-Fu

    2015-01-01

    Life science has a need for detection methods that are label-free and real-time. In this paper, we have selected staphylococcal protein A (SPA) and swine immunoglobulin G (IgG), and monitor the bindings between SPA and swine IgG with different concentrations, as well as the dissociations of SPA-swine IgG complex in different pH values of phosphate buffer by oblique-incidence reflectivity difference (OIRD) in a label-free and real-time fashion. We obtain the ON and OFF reaction dynamic curves corresponding to the bindings and dissociations of SPA and swine IgG. Through our analysis of the experimental results, we have been able to obtain the damping coefficients and the dissociation time of SPA and swine IgG for different pH values of the phosphate buffer. The results prove that the OIRD technique is a competing method for monitoring the dynamic processes of biomolecule interaction and achieving the quantitative information of reaction kinetics. (general)

  3. Comments on the variability of inherent bioelement contents of spruce needles

    International Nuclear Information System (INIS)

    Wyttenbach, A.; Tobler, L.; Bajo, S.

    1991-01-01

    Inherent needle contents are the relevant concentrations within the needle, excluding surface contaminations by aerosols. The error arising from the analysis of unwashed needles is quantified. For many elements it is the source of a large apparent variability. Spatial variability is discussed under the aspects of variability among trees within a plot and of variability among different plots. Both terms have implications as to the number of trees that should be sampled for the characterization of a plot. Variability with time is investigated by following the needle concentrations from an age of 1 to 23 months. The results give indications on favourable sampling dates and on the physiology of the different elements. All investigations refer to 20 elements, which have been determined by neutron activation analysis. (author) 6 figs., 5 tabs., 16 refs

  4. Application of the total reflection X-ray fluorescence method to the elemental analysis of brain tumors of different types and grades of malignancy

    International Nuclear Information System (INIS)

    Lankosz, M.W.; Grzelak, M.; Ostachowicz, B.; Wandzilak, A.; Szczerbowska-Boruchowska, M.; Wrobel, P.; Radwanska, E.; Adamek, D.

    2014-01-01

    The process of carcinogenesis may influence normal biochemical reactions leading to alterations in the elemental composition of the tissue. Total reflection X-ray fluorescence analysis (TXRF) was applied to the elemental analysis of different brain tumors. The following elements were present in all the neoplastic tissues analyzed: K, Ca, Fe, Cu, Zn and Rb. The results of the analysis showed that the elemental composition of a relatively small fragment of tissue represents satisfactorily the biochemical “signature” of a cancer. On the basis of the element concentrations determined, it was possible to differentiate between some types of brain tumors. - Highlights: • Elemental composition represents the biochemical signature of brain cancer. • The element levels differentiate some types of brain tumors. • TXRF spectrometry is a useful tool for elemental trace analysis of brain cancer

  5. Ulcerative colitis, Crohn's disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn's disease

    DEFF Research Database (Denmark)

    Mortensen, Joachim Høg; Manon-Jensen, Tina; Jensen, Michael Dam

    2017-01-01

    Increased protease activity is a key pathological feature of inflammatory bowel disease (IBD). However, the differences in extracellular matrix remodelling (ECM) in Crohn's disease (CD) and ulcerative colitis (UC) are not well described. An increased understanding of the inflammatory processes may...... provide optimized disease monitoring and diagnostics. We investigated the tissue remodelling in IBD and IBS patients by using novel blood-based biomarkers reflecting ECM remodelling. Five ECM biomarkers (VICM, BGM, EL-NE, C5M, Pro-C5) were measured by competitive ELISAs in serum from 72 CD patients, 60 UC...... patients, 22 patients with irritable bowel syndrome (IBS), and 24 healthy donors. One-way analysis of variance, Mann-Whitney U-test, logistic regression models, and receiver operator characteristics (ROC) curve analysis was carried out to evaluate the diagnostic accuracy of the biomarkers. The ECM...

  6. Reflection as Self-Assessment

    Science.gov (United States)

    Pappas, Marjorie L.

    2010-01-01

    In this article, the author discusses how reflection can be used as self-assessment. Reflection involves not only thinking about a learning experience, but also questioning parts of the experience. Reflection is thinking about what one knows from the learning experience, what one might do differently the next time. Reflection is wondering about…

  7. Chronic kidney disease: an inherent risk factor for acute kidney injury?

    Science.gov (United States)

    Singh, Prabhleen; Rifkin, Dena E; Blantz, Roland C

    2010-09-01

    Epidemiologic evidence suggests that chronic kidney disease (CKD) is a risk factor for acute kidney injury (AKI) due to the prevalence of CKD in patients who have episodes of AKI. However, the high burden of comorbidities such as age, diabetes, peripheral vascular, cardiovascular, and liver disease accompanying CKD, and the difficulties of defining AKI in the setting of CKD make these observations difficult to interpret. These comorbidities not only could alter the course of AKI but also may be the driving force behind the epidemiologic association between CKD and AKI because of systemic changes and/or increased exposure to potential nephrotoxic risks. Here, we contend that studies suggesting that CKD is a risk factor for AKI may suffer from residual confounding and reflect an overall susceptibility to illness rather than biologic susceptibility of the kidney parenchyma to injury. In support of our argument, we discuss the clinical evidence from epidemiologic studies, and the knowledge obtained from animal models on the pathophysiology of AKI and CKD, demonstrating a preconditioning influence of the previously impaired kidneys against subsequent injury. We conclude that, under careful analysis, factors apart from the inherent pathophysiology of the diseased kidney may be responsible for the increased frequency of AKI in CKD patients, and the impact of CKD on the risk and severity of AKI needs further investigation. Moreover, certain elements in the pathophysiology of a previously injured kidney may, surprisingly, bear out to be protective against AKI.

  8. Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells.

    Science.gov (United States)

    Huang, Szu-Han; Ren, Yanqin; Thomas, Allison S; Chan, Dora; Mueller, Stefanie; Ward, Adam R; Patel, Shabnum; Bollard, Catherine M; Cruz, Conrad Russell; Karandish, Sara; Truong, Ronald; Macedo, Amanda B; Bosque, Alberto; Kovacs, Colin; Benko, Erika; Piechocka-Trocha, Alicja; Wong, Hing; Jeng, Emily; Nixon, Douglas F; Ho, Ya-Chi; Siliciano, Robert F; Walker, Bruce D; Jones, R Brad

    2018-02-01

    The presence of persistent, latent HIV reservoirs in CD4+ T cells obstructs current efforts to cure infection. The so-called kick-and-kill paradigm proposes to purge these reservoirs by combining latency-reversing agents with immune effectors such as cytotoxic T lymphocytes. Support for this approach is largely based on success in latency models, which do not fully reflect the makeup of latent reservoirs in individuals on long-term antiretroviral therapy (ART). Recent studies have shown that CD8+ T cells have the potential to recognize defective proviruses, which comprise the vast majority of all infected cells, and that the proviral landscape can be shaped over time due to in vivo clonal expansion of infected CD4+ T cells. Here, we have shown that treating CD4+ T cells from ART-treated individuals with combinations of potent latency-reversing agents and autologous CD8+ T cells consistently reduced cell-associated HIV DNA, but failed to deplete replication-competent virus. These CD8+ T cells recognized and potently eliminated CD4+ T cells that were newly infected with autologous reservoir virus, ruling out a role for both immune escape and CD8+ T cell dysfunction. Thus, our results suggest that cells harboring replication-competent HIV possess an inherent resistance to CD8+ T cells that may need to be addressed to cure infection.

  9. Media for Reflection

    DEFF Research Database (Denmark)

    Knudsen, Morten

    2016-01-01

    This article develops the concept media for reflection in the interest of conceptualizing the interpretative frames that enable and limit reflection in management and leadership education. The concept ‘media for reflection’ allows us to conceptualize the social and cultural mediation of reflection...... without reducing reflection to an effect of the social structures and cultural norms in which it is embedded. Based on the developed theoretical framework, this article analyses how a renaissance ‘mirror for princes’ and contemporary research-based management education mediate reflection. The content...... of the mediations is analysed as well as the societal and organizational background. Furthermore, the means by which the two media enable and limit reflection in different ways is compared. Finally, the article discusses possible implications of the analysis in terms of management and leadership education....

  10. Relax! : inherent feedback during product interaction to reduce stress

    NARCIS (Netherlands)

    Bruns, M.

    2010-01-01

    For this research different experiments were conducted that indicate that people make rocking and rolling movements with a pen when they feel stressed; that when nervous movements are counteracted this results in more control over a situation; and that people prefer objects with moving parts when

  11. Impact of inherent meteorology uncertainty on air quality ...

    Science.gov (United States)

    It is well established that there are a number of different classifications and sources of uncertainties in environmental modeling systems. Air quality models rely on two key inputs, namely, meteorology and emissions. When using air quality models for decision making, it is important to understand how uncertainties in these inputs affect the simulated concentrations. Ensembles are one method to explore how uncertainty in meteorology affects air pollution concentrations. Most studies explore this uncertainty by running different meteorological models or the same model with different physics options and in some cases combinations of different meteorological and air quality models. While these have been shown to be useful techniques in some cases, we present a technique that leverages the initial condition perturbations of a weather forecast ensemble, namely, the Short-Range Ensemble Forecast system to drive the four-dimensional data assimilation in the Weather Research and Forecasting (WRF)-Community Multiscale Air Quality (CMAQ) model with a key focus being the response of ozone chemistry and transport. Results confirm that a sizable spread in WRF solutions, including common weather variables of temperature, wind, boundary layer depth, clouds, and radiation, can cause a relatively large range of ozone-mixing ratios. Pollutant transport can be altered by hundreds of kilometers over several days. Ozone-mixing ratios of the ensemble can vary as much as 10–20 ppb

  12. Impact of inherent meteorology uncertainty on air quality model predictions

    Science.gov (United States)

    It is well established that there are a number of different classifications and sources of uncertainties in environmental modeling systems. Air quality models rely on two key inputs, namely, meteorology and emissions. When using air quality models for decision making, it is impor...

  13. Reflectance Modeling

    Science.gov (United States)

    Smith, J. A.; Cooper, K.; Randolph, M.

    1984-01-01

    A classical description of the one dimensional radiative transfer treatment of vegetation canopies was completed and the results were tested against measured prairie (blue grama) and agricultural canopies (soybean). Phase functions are calculated in terms of directly measurable biophysical characteristics of the canopy medium. While the phase functions tend to exhibit backscattering anisotropy, their exact behavior is somewhat more complex and wavelength dependent. A Monte Carlo model was developed that treats soil surfaces with large periodic variations in three dimensions. A photon-ray tracing technology is used. Currently, the rough soil surface is described by analytic functions and appropriate geometric calculations performed. A bidirectional reflectance distribution function is calculated and, hence, available for other atmospheric or canopy reflectance models as a lower boundary condition. This technique is used together with an adding model to calculate several cases where Lambertian leaves possessing anisotropic leaf angle distributions yield non-Lambertian reflectance; similar behavior is exhibited for simulated soil surfaces.

  14. Reflection: A Socratic approach.

    Science.gov (United States)

    Van Seggelen-Damen, Inge C M; Van Hezewijk, René; Helsdingen, Anne S; Wopereis, Iwan G J H

    2017-12-01

    Reflection is a fuzzy concept. In this article we reveal the paradoxes involved in studying the nature of reflection. Whereas some scholars emphasize its discursive nature, we go further and underline its resemblance to the self-biased dialogue Socrates had with the slave in Plato's Meno . The individual and internal nature of the reflection process creates difficulty for studying it validly and reliably. We focus on methodological issues and use Hans Linschoten's view of coupled systems to identify, analyze, and interpret empirical research on reflection. We argue that researchers and research participants can take on roles in several possible system couplings. Depending on who controls the manipulation of the stimulus, who controls the measuring instrument, who interprets the measurement and the response, different types of research questions can be answered. We conclude that reflection may be validly studied by combining different couplings of experimenter, manipulation, stimulus, participant, measurement, and response.

  15. Reflective optics

    CERN Document Server

    Korsch, Dietrich

    1991-01-01

    This is the first book dedicated exclusively to all-reflective imaging systems. It is a teaching tool as well as a practical design tool for anyone who specializes in optics, particularly for those interested in telescopes, infrared, and grazing-incidence systems. The first part of the book describes a unified geometric optical theory of all-reflective imaging systems (from near-normal to grazing incidence) developed from basic principles. The second part discusses correction methods and a multitude of closed-form solutions of well-corrected systems, supplemented with many conventional and unc

  16. Dynamic operator actions analysis for inherently safe fast reactors and light water reactors

    International Nuclear Information System (INIS)

    Ho, V.; Apostolakis, G.

    1988-01-01

    A comparative dynamic human actions analysis of inherently safe fast reactors (ISFRs) and light water reactors (LWRs) in terms of systems response and estimated human error rates is presented. Brief overviews of the ISFR and LWR systems are given to illustrate the design differences. Key operator actions required by the ISFR reactor shutdown and decay heat removal systems are identified and are compared with those of the LWR. It is observed that, because of the passive nature of the ISFR safety-related systems, a large time window is available for operator actions during transient events. Furthermore, these actions are fewer in number, are less complex, and have lower error rates and less severe consequences than those of the LWRs. We expect the ISFR operator errors' contribution to risk is smaller (at least in the context of the existing human reliability models) than that of the LWRs. (author)

  17. Effect of vital bleaching with solutions containing different concentrations of hydrogen peroxide and pineapple extract as an additive on human enamel using reflectance spectrophotometer: An in vitro study.

    Science.gov (United States)

    Vejai Vekaash, Chitra Janardhanan; Kumar Reddy, Tripuravaram Vinay; Venkatesh, Kondas Vijay

    2017-01-01

    This study aims to evaluate the color change in human enamel bleached with three different concentrations of hydrogen peroxide, containing pineapple extract as an additive in two different timings, using reflectance spectrophotometer. The study aimed to investigate the bleaching efficacy on natural teeth using natural enzymes. Baseline color values of 10 randomly selected artificially stained incisors were obtained. The specimens were divided into three groups of 20 teeth each: Group 1 - 30% hydrogen peroxide, Group II - 20% hydrogen peroxide, and Group III - 10% hydrogen peroxide. One half of the tooth was bleached with hydrogen peroxide, and other was bleached with hydrogen peroxide and pineapple extract for 20 min (Subgroup A) and 10 min (Subgroup B). The results were statistically analyzed using student's t -test. The mean ΔE values of Group IA (31.62 ± 0.9), Group IIA (29.85 ± 1.2), and Group IIIA (28.65 ± 1.2) showed statistically significant higher values when compared to the mean Δ E values of Group 1A (25.02 ± 1.2), Group IIA (22.86 ± 1.1), and Group IIIA (16.56 ± 1.1). Identical results were obtained in Subgroup B. The addition of pineapple extract to hydrogen peroxide resulted in effective bleaching.

  18. Naturally occurring stable isotopes reflect changes in protein turnover and growth in gilthead sea bream (Sparus aurata) juveniles under different dietary protein levels.

    Science.gov (United States)

    Martin-Perez, Miguel; Fernandez-Borras, Jaume; Ibarz, Antoni; Felip, Olga; Fontanillas, Ramon; Gutierrez, Joaquim; Blasco, Josefina

    2013-09-18

    Ideal nutritional conditions are crucial to sustainable aquaculture due to economic and environmental issues. Here we apply stable isotope analysis as an indicator of fish growth and feeding balance, to define the optimum diet for efficient growing conditions. Juveniles of gilthead sea bream were fed with six isoenergetic diets differing in protein to lipid proportion (from 41/26 to 57/20). As protein intake increased, δ¹⁵N and Δδ¹⁵N of muscle and Δδ¹⁵N and Δδ¹³C of its protein fraction decreased, indicating lower protein turnover and higher protein deposition in muscle. This is reflected in the inverse relationship found between Δδ¹⁵N and growth rate, although no differences were observed in either parameter beyond the protein/lipid proportion 47/23. Principal component analysis (PCA) also signaled 47/23 diet as the pivotal point with the highest growing efficiency, with isotopic parameters having the highest discrimination load. Thus, muscle isotope composition, especially ¹⁵N, can be used to evaluate nutritional status in farmed fish.

  19. The inherent complexity in nonlinear business cycle model in resonance

    International Nuclear Information System (INIS)

    Ma Junhai; Sun Tao; Liu Lixia

    2008-01-01

    Based on Abraham C.-L. Chian's research, we applied nonlinear dynamic system theory to study the first-order and second-order approximate solutions to one category of the nonlinear business cycle model in resonance condition. We have also analyzed the relation between amplitude and phase of second-order approximate solutions as well as the relation between outer excitements' amplitude, frequency approximate solutions, and system bifurcation parameters. Then we studied the system quasi-periodical solutions, annulus periodical solutions and the path leading to system bifurcation and chaotic state with different parameter combinations. Finally, we conducted some numerical simulations for various complicated circumstances. Therefore this research will lay solid foundation for detecting the complexity of business cycles and systems in the future

  20. Is the Rational Addiction model inherently impossible to estimate?

    Science.gov (United States)

    Laporte, Audrey; Dass, Adrian Rohit; Ferguson, Brian S

    2017-07-01

    The Rational Addiction (RA) model is increasingly often estimated using individual level panel data with mixed results; in particular, with regard to the implied rate of time discount. This paper suggests that the odd values of the rate of discount frequently found in the literature may in fact be a consequence of the saddle-point dynamics associated with individual level inter-temporal optimization problems. We report the results of Monte Carlo experiments estimating RA-type difference equations that seem to suggest the possibility that the presence of both a stable and an unstable root in the dynamic process may create serious problems for the estimation of RA equations. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Concept of an inherently-safe high temperature gas-cooled reactor

    International Nuclear Information System (INIS)

    Ohashi, Hirofumi; Sato, Hiroyuki; Tachibana, Yukio; Kunitomi, Kazuhiko; Ogawa, Masuro

    2012-01-01

    As the challenge to ensure no harmful release of radioactive materials at the accidents by deterministic approach instead to satisfy acceptance criteria or safety goal for risk by probabilistic approach, new concept of advanced reactor, an inherently-safe high temperature gas-cooled reactor, is proposed based on the experience of the operation of the actual High Temperature Gas-cooled Reactor (HTGR) in Japan, High Temperature Engineering Test Reactor (HTTR), and the design of the commercial plant (GTHTR300), utilizing the inherent safety features of the HTGR (i.e., safety features based on physical phenomena). The safety design philosophy of the inherently-safe HTGR for the safety analysis of the radiological consequences is determined as the confinement of radioactive materials is assured by only inherent safety features without engineered safety features, AC power or prompt actions by plant personnel if the design extension conditions occur. Inherent safety features to prevent the loss or degradation of the confinement function are identified. It is proposed not to apply the probabilistic approach for the evaluation of the radiological consequences of the accidents in the safety analysis because no inherent safety features fail for the mitigation of the consequences of the accidents. Consequently, there are no event sequences to harmful release of radioactive materials if the design extension conditions occur in the inherently-safe HTGR concept. The concept and future R and D items for the inherently-safe HTGR are described in this paper.

  2. Inherent reward & risk (Part I): Towards a universal paradigm for investment analysis

    NARCIS (Netherlands)

    Zou, L.

    2000-01-01

    In this paper, a new paradigm is developed for analyzinginvestment strategies and pricing financial assets. This paradigmassumes that any investment strategy has its own "inherent reward"and "inherent risk" that can be judged with common sense. Ijustify axiomatically the existence and uniqueness

  3. A case for inherent geometric and geodetic accuracy in remotely sensed VNIR and SWIR imaging products

    Science.gov (United States)

    Driver, J. M.

    1982-01-01

    Significant aberrations can occur in acquired images which, unless compensated on board the spacecraft, can seriously impair throughput and timeliness for typical Earth observation missions. Conceptual compensations options are advanced to enable acquisition of images with inherent geometric and geodetic accuracy. Research needs are identified which, when implemented, can provide inherently accurate images. Agressive pursuit of these research needs is recommended.

  4. Inherent lipid metabolic dysfunction in glycogen storage disease IIIa.

    Science.gov (United States)

    Li, Xin-Hua; Gong, Qi-Ming; Ling, Yun; Huang, Chong; Yu, De-Min; Gu, Lei-Lei; Liao, Xiang-Wei; Zhang, Dong-Hua; Hu, Xi-Qi; Han, Yue; Kong, Xiao-Fei; Zhang, Xin-Xin

    2014-12-05

    We studied two patients from a nonconsanguineous family with life-long abnormal liver function, hepatomegaly and abnormal fatty acid profiles. Abnormal liver function, hypoglycemia and muscle weakness are observed in various genetic diseases, including medium-chain acyl-CoA dehydrogenase (MCAD) deficiency and glycogen storage diseases. The proband showed increased free fatty acids, mainly C8 and C10, resembling fatty acid oxidation disorder. However, no mutation was found in ACADM and ACADL gene. Sequencing of theamylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase (AGL) gene showed that both patients were compound heterozygotes for c.118C > T (p.Gln40X) and c.753_756 del CAGA (p.Asp251Glufsx29), whereas their parents were each heterozygous for one of these mutations. The AGL protein was undetectable in EBV-B cells from the two patients. Transcriptome analysis demonstrated a significant different pattern of gene expression in both of patients’ cells, including genes involving in the PPAR signaling pathway, fatty acid biosynthesis, lipid synthesis and visceral fat deposition and metabolic syndrome. This unique gene expression pattern is probably due to the absence of AGL, which potentially accounts for the observed clinical phenotypes of hyperlipidemia and hepatocyte steatosis in glycogen storage disease type IIIa.

  5. Our Selections and Decisions: Inherent Features of the Nervous System?

    Science.gov (United States)

    Rösler, Frank

    The chapter summarizes findings on the neuronal bases of decisionmaking. Taking the phenomenon of selection it will be explained that systems built only from excitatory and inhibitory neuron (populations) have the emergent property of selecting between different alternatives. These considerations suggest that there exists a hierarchical architecture with central selection switches. However, in such a system, functions of selection and decision-making are not localized, but rather emerge from an interaction of several participating networks. These are, on the one hand, networks that process specific input and output representations and, on the other hand, networks that regulate the relative activation/inhibition of the specific input and output networks. These ideas are supported by recent empirical evidence. Moreover, other studies show that rather complex psychological variables, like subjective probability estimates, expected gains and losses, prediction errors, etc., do have biological correlates, i.e., they can be localized in time and space as activation states of neural networks and single cells. These findings suggest that selections and decisions are consequences of an architecture which, seen from a biological perspective, is fully deterministic. However, a transposition of such nomothetic functional principles into the idiographic domain, i.e., using them as elements for comprehensive 'mechanistic' explanations of individual decisions, seems not to be possible because of principle limitations. Therefore, individual decisions will remain predictable by means of probabilistic models alone.

  6. Inherent noise can facilitate coherence in collective swarm motion

    KAUST Repository

    Yates, C. A.; Erban, R.; Escudero, C.; Couzin, I. D.; Buhl, J.; Kevrekidis, I. G.; Maini, P. K.; Sumpter, D. J. T.

    2009-01-01

    Among the most striking aspects of the movement of many animal groups are their sudden coherent changes in direction. Recent observations of locusts and starlings have shown that this directional switching is an intrinsic property of their motion. Similar direction switches are seen in self-propelled particle and other models of group motion. Comprehending the factors that determine such switches is key to understanding the movement of these groups. Here, we adopt a coarse-grained approach to the study of directional switching in a self-propelled particle model assuming an underlying one-dimensional Fokker-Planck equation for the mean velocity of the particles. We continue with this assumption in analyzing experimental data on locusts and use a similar systematic Fokker-Planck equation coefficient estimation approach to extract the relevant information for the assumed Fokker-Planck equation underlying that experimental data. In the experiment itself the motion of groups of 5 to 100 locust nymphs was investigated in a homogeneous laboratory environment, helping us to establish the intrinsic dynamics of locust marching bands. We determine the mean time between direction switches as a function of group density for the experimental data and the self-propelled particle model. This systematic approach allows us to identify key differences between the experimental data and the model, revealing that individual locusts appear to increase the randomness of their movements in response to a loss of alignment by the group. We give a quantitative description of how locusts use noise to maintain swarm alignment. We discuss further how properties of individual animal behavior, inferred by using the Fokker-Planck equation coefficient estimation approach, can be implemented in the self-propelled particle model to replicate qualitatively the group level dynamics seen in the experimental data.

  7. Inherent noise can facilitate coherence in collective swarm motion

    KAUST Repository

    Yates, C. A.

    2009-03-31

    Among the most striking aspects of the movement of many animal groups are their sudden coherent changes in direction. Recent observations of locusts and starlings have shown that this directional switching is an intrinsic property of their motion. Similar direction switches are seen in self-propelled particle and other models of group motion. Comprehending the factors that determine such switches is key to understanding the movement of these groups. Here, we adopt a coarse-grained approach to the study of directional switching in a self-propelled particle model assuming an underlying one-dimensional Fokker-Planck equation for the mean velocity of the particles. We continue with this assumption in analyzing experimental data on locusts and use a similar systematic Fokker-Planck equation coefficient estimation approach to extract the relevant information for the assumed Fokker-Planck equation underlying that experimental data. In the experiment itself the motion of groups of 5 to 100 locust nymphs was investigated in a homogeneous laboratory environment, helping us to establish the intrinsic dynamics of locust marching bands. We determine the mean time between direction switches as a function of group density for the experimental data and the self-propelled particle model. This systematic approach allows us to identify key differences between the experimental data and the model, revealing that individual locusts appear to increase the randomness of their movements in response to a loss of alignment by the group. We give a quantitative description of how locusts use noise to maintain swarm alignment. We discuss further how properties of individual animal behavior, inferred by using the Fokker-Planck equation coefficient estimation approach, can be implemented in the self-propelled particle model to replicate qualitatively the group level dynamics seen in the experimental data.

  8. Contrasting Inherent Optical Properties and Carbon Metabolism Between Five Northeastern (USA) Estuary-plume Systems

    Science.gov (United States)

    Vandemark, Doug; Salisbury, Joe; Hunt, Chris; McGillis, Wade R.

    2004-01-01

    We have recently developed the ability to rapidly assess Surface inherent optical properties (IOP), oxygen concentration and pCO2 in estuarine-plume systems using flow-through instrumentation. During the summer of 2004, several estuarine-plume systems were surveyed which include the Pleasant (ME), Penobscot (ME), Kennebec-Androscoggin (ME), Merrimack (NH-MA) and Hudson (NY). Continuous measurements of surface chlorophyll and colored dissolved organic carbon (CDOM) fluorescence, beam attenuation, temperature, salinity, oxygen and pC02 were taken at each system along a salinity gradient from fresh water to near oceanic endmembers. CTD and IOP profiles were also taken at predetermined surface salinity intervals. These were accompanied by discrete determinations of chlorophyll (HPLC and fluorometric), total suspended solids (TSS), dissolved organic carbon (DOC) and alkalinity. IOP data were calibrated using chlorophyll, DOC and TSS data to enable the retrieval of these constituents from IOP data. Considerable differences in the data sets were observed between systems. These ranged from the DOC-enriched, strongly heterotrophic Pleasant River System to the high-chlorophyll autotrophic Merrimack River System. Using pCO2 and oxygen saturation measurements as proxies for water column metabolism, distinct relationships were found between trophic status and inherent optical properties. The nature of these relationships varies between systems and is likely a function of watershed and estuarine attributes including carbon and nutrient loading, in-situ production and related autochthonous inputs of DOC and alkalinity. Our results suggest that IOP data may contain significant information about the trophic status of estuarine and plume systems.

  9. Nuclear desalination in the Arab world - Part II: Advanced inherent and passive safe nuclear reactors

    International Nuclear Information System (INIS)

    Karameldin, A.; Samer S. Mekhemar

    2004-01-01

    Rapid increases in population levels have led to greater demands for fresh water and electricity in the Arab World. Different types of energies are needed to contribute to bridging the gap between increased demand and production. Increased levels of safeguards in nuclear power plants have became reliable due to their large operational experience, which now exceeds 11,000 years of operation. Thus, the nuclear power industry should be attracting greater attention. World electricity production from nuclear power has risen from 1.7% in 1970 to 17%-20% today. This ratio had increased in June 2002 to reach more than 30%, 33% and 42% in Europe, Japan, and South Korea respectively. In the Arab World, both the public acceptance and economic viability of nuclear power as a major source of energy are greatly dependent on the achievement of a high level of safety and environmental protection. An assessment of the recent generation of advanced reactor safety criteria requirements has been carried out. The promising reactor designs adapted for the Arab world and other similar developing countries are those that profit from the enhanced and passive safety features of the new generation of reactors, with a stronger focus on the effective use of intrinsic characteristics, simplified plant design, and easy construction, operation and maintenance. In addition, selected advanced reactors with a full spectrum from small to large capacities, and from evolutionary to radical types, which have inherent and passive safety features, are discussed. The relevant economic assessment of these reactors adapted for water/electricity cogeneration have been carried out and compared with non-nuclear desalination methods. This assessment indicates that, water/electricity cogeneration by the nuclear method with advanced inherent and passive safe nuclear power plants, is viable and competitive. (author)

  10. The inherent weaknesses in industrial control systems devices; hacking and defending SCADA systems

    Science.gov (United States)

    Bianco, Louis J.

    The North American Electric Reliability Corporation (NERC) is about to enforce their NERC Critical Infrastructure Protection (CIP) Version Five and Six requirements on July 1st 2016. The NERC CIP requirements are a set of cyber security standards designed to protect cyber assets essential the reliable operation of the electric grid. The new Version Five and Six requirements are a major revision to the Version Three (currently enforced) requirements. The new requirements also bring substations into scope alongside Energy Control Centers. When the Version Five requirements were originally drafted they were vague, causing in depth discussions throughout the industry. The ramifications of these requirements has made owners look at their systems in depth, questioning how much money it will take to meet these requirements. Some owners saw backing down from routable networks to non-routable as a means to save money as they would be held to less requirements within the standards. Some owners saw removing routable connections as a proper security move. The purpose of this research was to uncover the inherent weaknesses in Industrial Control Systems (ICS) devices; to show how ICS devices can be hacked and figure out potential protections for these Critical Infrastructure devices. In addition, this research also aimed to validate the decision to move from External Routable connectivity to Non-Routable connectivity, as a security measure and not as a means of savings. The results reveal in order to ultimately protect Industrial Control Systems they must be removed from the Internet and all bi-directional external routable connections must be removed. Furthermore; non-routable serial connections should be utilized, and these non-routable serial connections should be encrypted on different layers of the OSI model. The research concluded that most weaknesses in SCADA systems are due to the inherent weaknesses in ICS devices and because of these weaknesses, human intervention is

  11. The nature of inherent bactericidal activity: insights from the nanotopology of three species of dragonfly

    Science.gov (United States)

    Mainwaring, David E.; Nguyen, Song Ha; Webb, Hayden; Jakubov, Timur; Tobin, Mark; Lamb, Robert N.; Wu, Alex H.-F.; Marchant, Richard; Crawford, Russell J.; Ivanova, Elena P.

    2016-03-01

    While insect wings are widely recognised as multi-functional, recent work showed that this extends to extensive bactericidal activity brought about by cell deformation and lysis on the wing nanotopology. We now quantitatively show that subtle changes to this topography result in substantial changes in bactericidal activity that are able to span an order of magnitude. Notably, the chemical composition of the lipid nanopillars was seen by XPS and synchrotron FTIR microspectroscopy to be similar across these activity differences. Modelling the interaction between bacterial cells and the wing surface lipids of 3 species of dragonflies, that inhabit similar environments, but with distinctly different behavioural repertoires, provided the relationship between surface structure and antibacterial functionality. In doing so, these principal behavioural patterns correlated with the demands for antimicrobial efficiency dictated by differences in their foraging strategies. This work now reveals a new feature in the design elegance of natural multi-functional surfaces as well providing insights into the bactericidal mechanism underlying inherently antimicrobial materials, while suggesting that nanotopology is related to the evolutionary development of a species through the demands of its behavioural repertoire. The underlying relationship between the processes of wetting, adhesion and capillarity of the lipid nanopillars and bactericidal efficiency suggests new prospects for purely mechano-responsive antibacterial surfaces.While insect wings are widely recognised as multi-functional, recent work showed that this extends to extensive bactericidal activity brought about by cell deformation and lysis on the wing nanotopology. We now quantitatively show that subtle changes to this topography result in substantial changes in bactericidal activity that are able to span an order of magnitude. Notably, the chemical composition of the lipid nanopillars was seen by XPS and synchrotron

  12. Bacterial diversity shift determined by different diets in the gut of the spotted wing fly Drosophila suzukii is primarily reflected on acetic acid bacteria

    KAUST Repository

    Vacchini, Violetta

    2016-11-25

    The pivotal role of diet in shaping gut microbiota has been evaluated in different animal models, including insects. Drosophila flies harbour an inconstant microbiota among which acetic acid bacteria (AAB) are important components. Here, we investigated the bacterial and AAB components of the invasive pest Drosophila suzukii microbiota, by studying the same insect population separately grown on fruit-based or non-fruit artificial diet. AAB were highly prevalent in the gut under both diets (90 and 92% infection rates with fruits and artificial diet, respectively). Fluorescent in situ hybridization and recolonization experiments with green fluorescent protein (Gfp)-labelled strains showed AAB capability to massively colonize insect gut. High-throughput sequencing on 16S rRNA gene indicated that the bacterial microbiota of guts fed with the two diets clustered separately. By excluding AAB-related OTUs from the analysis, insect bacterial communities did not cluster separately according to the diet, suggesting that diet-based diversification of the community is primarily reflected on the AAB component of the community. Diet influenced also AAB alpha-diversity, with separate OTU distributions based on diets. High prevalence, localization and massive recolonization, together with AAB clustering behaviour in relation to diet, suggest an AAB role in the D. suzukii gut response to diet modification. This article is protected by copyright. All rights reserved.

  13. Initial and noninitial name-letter preferences as obtained through repeated letter rating tasks continue to reflect (different aspects of) self-esteem.

    Science.gov (United States)

    Hoorens, Vera; Takano, Keisuke; Franck, Erik; Roberts, John E; Raes, Filip

    2015-09-01

    We tested the usefulness of name-letter preference scores as indirect indicators of self-esteem by exploring whether multiple unsupervised self-administrations of letter rating tasks within a short period of time yield useful data. We also examined whether preferences for initials and noninitial name-letters tap different aspects of self-esteem. Participants from a community sample (N = 164; 58 men and 106 women, 17-67 years, Mage = 34.57, SD = 13.28) completed daily letter rating tasks and state self-esteem questionnaires for 7 consecutive days. They also completed a trait self-esteem questionnaire on the first measurement day as well as 6 months later. Preference scores for first-name initials were stronger but more unstable than preference scores for other name-letters. Preferences for first-name initials were primarily associated with directly measured state self-esteem whereas preferences for noninitials were primarily associated with directly measured trait self-esteem even if the latter was measured 6 months later. Thus, we showed that preferences for initials and noninitials are not simply interchangeable. Previous letter rating studies, which almost exclusively used initial preferences, should be interpreted in terms of state rather than trait self-esteem. In future studies, researchers should focus on the name-letter preference that reflects the aspect of self-esteem they wish to address. (c) 2015 APA, all rights reserved.

  14. Real-Time, Label-Free Detection of Biomolecular Interactions in Sandwich Assays by the Oblique-Incidence Reflectivity Difference Technique

    Directory of Open Access Journals (Sweden)

    Yung-Shin Sun

    2014-12-01

    Full Text Available One of the most important goals in proteomics is to detect the real-time kinetics of diverse biomolecular interactions. Fluorescence, which requires extrinsic tags, is a commonly and widely used method because of its high convenience and sensitivity. However, in order to maintain the conformational and functional integrality of biomolecules, label-free detection methods are highly under demand. We have developed the oblique-incidence reflectivity difference (OI-RD technique for label-free, kinetic measurements of protein-biomolecule interactions. Incorporating the total internal refection geometry into the OI-RD technique, we are able to detect as low as 0.1% of a protein monolayer, and this sensitivity is comparable with other label-free techniques such as surface plasmon resonance (SPR. The unique advantage of OI-RD over SPR is no need for dielectric layers. Moreover, using a photodiode array as the detector enables multi-channel detection and also eliminates the over-time signal drift. In this paper, we demonstrate the applicability and feasibility of the OI-RD technique by measuring the kinetics of protein-protein and protein-small molecule interactions in sandwich assays.

  15. Systemic and lung protein changes in sarcoidosis. Lymphocyte counts, gallium uptake values, and serum angiotensin-converting enzyme levels may reflect different aspects of disease activity

    International Nuclear Information System (INIS)

    Check, I.J.; Kidd, M.R.; Staton, G.W. Jr.

    1986-01-01

    BAL lymphocyte percentages, quantitated gallium-67 lung uptake, and SACE levels have all been proposed as measures of disease activity in sarcoidosis. We analyzed 32 paired sera and BAL fluids from sarcoidosis patients by high-resolution agarose electrophoresis to look for protein changes characteristic of systemic or local inflammation and compared the results with those from the above tests. Nine patients (group 1) had serum inflammatory protein changes and increased total protein, albumin, beta 1-globulin (transferrin), and gamma-globulin levels in fluid recovered by BAL. Thirteen patients (group 2) had normal protein levels in sera but abnormal protein levels in BAL specimens. Ten patients (group 3) had normal protein levels in sera and in BAL specimens. Patients in groups 1 and 2 had a disproportionate increase in beta 1-globulin (transferrin) and gamma-globulin levels in their BAL specimens. The BAL lymphocyte percentage changes paralleled the BAL protein level changes, suggesting relationships among the immunoregulatory role of these cells, increased local immunoglobulin synthesis, and the pathogenesis of altered alveolar permeability. Gallium-67 uptake was highest in patients with serum inflammatory protein changes. Thus, systemic inflammation may facilitate pulmonary gallium-67 uptake, possibly by changes in BAL fluid or serum transferrin saturation and/or kinetics. SACE levels showed no relationship to changes in the levels of serum or BAL proteins. These data suggest that the various proposed measures of disease activity reflect different aspects of inflammation in sarcoidosis

  16. Reflective Efficacy

    Directory of Open Access Journals (Sweden)

    Carla Bagnoli

    2018-04-01

    Full Text Available The purpose of this paper is to highlight some difficulties of Neil Sinhababu’s Humean theory of agency, which depend on his radically reductivist approach, rather than to his Humean sympathies. The argument is that Sinhababu’s theory builds upon a critique of reflective agency which is based on equivocation and misunderstandings of the Kantian approach. Ultimately, the objection is that his reductivist view is unequipped to address the rclassical problems of rational deliberation and agential authority.

  17. On the limits of Kagan's impulsive reflective distinction.

    Science.gov (United States)

    Jones, B; McIntyre, L

    1976-05-01

    A logical analysis is made of the Matching Familiar Figures (MFF) Test on the basis of which children have been classified as "impulsive" or "reflective." The reflective strategy is implicitly preferred to the impulsive because the reflective child makes fewer errors though generally taking longer to make his first response. We show that the test allows the choice of a number of "game plans" and speed-accuracy tradeoffs which in practice may not be very different. Error rates may not indicate perceptual sensitivity, in any case, since sensitivity and response factors may be confounded in the error rate. Using a visual running-memory-span task to avoid the inherent difficulties of the MFF test, we found that children previously classified on the basis of that test as impulsive or reflective did not differ in recognition accuracy but did differ in response bias and response latency. Accuracy and bias are estimated by way of Luce's choice theory (Luce, 1963), and the results are discussed in those terms.

  18. Finite-time and fixed-time leader-following consensus for multi-agent systems with discontinuous inherent dynamics

    Science.gov (United States)

    Ning, Boda; Jin, Jiong; Zheng, Jinchuan; Man, Zhihong

    2018-06-01

    This paper is concerned with finite-time and fixed-time consensus of multi-agent systems in a leader-following framework. Different from conventional leader-following tracking approaches where inherent dynamics satisfying the Lipschitz continuous condition is required, a more generalised case is investigated: discontinuous inherent dynamics. By nonsmooth techniques, a nonlinear protocol is first proposed to achieve the finite-time leader-following consensus. Then, based on fixed-time stability strategies, the fixed-time leader-following consensus problem is solved. An upper bound of settling time is obtained by using a new protocol, and such a bound is independent of initial states, thereby providing additional options for designers in practical scenarios where initial conditions are unavailable. Finally, numerical simulations are provided to demonstrate the effectiveness of the theoretical results.

  19. Inspiring Reflections

    DEFF Research Database (Denmark)

    Muchie, Mammo

    2011-01-01

    A numberof Chris Freeman's colleagues were asked to reflect on what they thought describes his life and work in a few words. Some of the colleagues replied including former SPRU students that were taught or supervised by Chris Freeman. Their views on what they thought were Chris Freeman's defining...... life is not free from fluctuations, cycles, disruptions, crises and destructions both human and ecological. Innovation research ought to position itself to address environmental, financial and economic crises. The third is innovation research for development by addressing not only poverty erdaication...

  20. Reflective Writing

    DEFF Research Database (Denmark)

    Ahrenkiel Jørgensen, Andriette

    2016-01-01

    In Breve fra min Have (Letters from my Garden), the Swedish landscape architect, Sven-Ingvar Andersson, produces dialogues about his garden to a wide circle of friends, colleagues, deceased and still living acquaintances such as Karen Blixen, Gertrude Stein, C. Th. Sørensen, Albrecht Dürer, Peter...... Høeg etetera. The dialogues work as a tool of reflection in terms of providing opportunity to examine his own beliefs, to explore the possible reasons for engaging in a particular activity. On the basis of Sven-Ingvar Andersson’s book a teaching program at the Aarhus School of Architecture provides...

  1. Reflective Packaging

    Science.gov (United States)

    1994-01-01

    The aluminized polymer film used in spacecraft as a radiation barrier to protect both astronauts and delicate instruments has led to a number of spinoff applications. Among them are aluminized shipping bags, food cart covers and medical bags. Radiant Technologies purchases component materials and assembles a barrier made of layers of aluminized foil. The packaging reflects outside heat away from the product inside the container. The company is developing new aluminized lines, express mailers, large shipping bags, gel packs and insulated panels for the building industry.

  2. Long range stress correlations in the inherent structures of liquids at rest

    Energy Technology Data Exchange (ETDEWEB)

    Chowdhury, Sadrul; Abraham, Sneha; Hudson, Toby; Harrowell, Peter [School of Chemistry, University of Sydney, Sydney, NSW 2006 (Australia)

    2016-03-28

    Simulation studies of the atomic shear stress in the local potential energy minima (inherent structures) are reported for binary liquid mixtures in 2D and 3D. These inherent structure stresses are fundamental to slow stress relaxation and high viscosity in supercooled liquids. We find that the atomic shear stress in the inherent structures (IS’s) of both liquids at rest exhibits slowly decaying anisotropic correlations. We show that the stress correlations contribute significantly to the variance of the total shear stress of the IS configurations and consider the origins of the anisotropy and spatial extent of the stress correlations.

  3. The role of passive and inherent safety properties in Siemens/KWU nuclear power plants

    International Nuclear Information System (INIS)

    Gremm, O.

    1990-01-01

    In Siemens/KWU Nuclear Power Plants the applied safety concept consist of a well balanced combination of active, passive use well is inherent safety measures. In principle it is not possible to realise a safety concept exclusively with inherent and/or passive safety properties. The respective measures and arguments will be explained in detail in the presentation. In addition the Siemens/KWU safety concept with examples of the role of inherent and passive safety measures will be illustrated. (author). 9 refs, 9 figs

  4. Behavioral measures of risk tasking, sensation seeking and sensitivity to reward may reflect different motivations for spicy food liking and consumption.

    Science.gov (United States)

    Byrnes, Nadia K; Hayes, John E

    2016-08-01

    Based on work a quarter century ago, it is widely accepted personality traits like sensation seeking are related to the enjoyment and intake of spicy foods; however, data supporting this belief is actually quite limited. Recently, we reported strong to moderate correlations between remembered spicy food liking and two personality traits measured with validated questionnaires. Here, participants consumed capsaicin-containing strawberry jelly to generate acute estimates of spicy food liking. Additionally, we used a laboratory-based behavioral measure of risk taking (the mobile Balloon Analogue Risk Task; mBART) to complement a range of validated self-report measures of risk-related personality traits. Present data confirm Sensation Seeking correlates with overall spicy meal liking and liking of the burn of a spicy meal, and extends prior findings by showing novel correlations with the liking of sampled stimuli. Other personality measures, including Sensitivity to Punishment (SP), Sensitivity to Reward (SR), and the Impulsivity and Risk Taking subscales of the DSM5 Personality Inventory (PID-5) did not show significant relationships with liking of spicy foods, either sampled or remembered. Our behavioral risk taking measure, the mBART, also failed to show a relationship with remembered or sampled liking. However, significant relationships were observed between reported intake of spicy foods and Sensitivity to Reward, and the Risk Taking subscale of the PID-5 (PID5-RT). Based on the observed patterns among various personality measures, and spicy food liking and intake, we propose that personality measures may exert their influence on intake of spicy food via different mechanisms. We also speculate that Sensation Seeking may reflect motivations for consuming spicy foods that are more intrinsic, while the motivations for eating spicy foods measured by SR and PID5-RT may be more extrinsic. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Neutron reflectivity

    Directory of Open Access Journals (Sweden)

    Cousin Fabrice

    2015-01-01

    Full Text Available The specular neutron reflectivity is a technique enabling the measurement of neutron scattering length density profile perpendicular to the plane of a surface or an interface, and thereby the profile of chemical composition. The characteristic sizes that are probed range from around 5 Å up 5000 Å. It is a scattering technique that averages information on the entire surface and it is therefore not possible to obtain information within the plane of the interface. The specific properties of neutrons (possibility of tuning the contrast by isotopic substitution, sensitivity to magnetism, negligible absorption, low energy of the incident neutrons makes it particularly interesting in the fields of soft matter, biophysics and magnetic thin films. This course is a basic introduction to the technique and does not address the magnetic reflectivity. It is composed of three parts describing respectively its principle and its formalism, the experimental aspects of the method (spectrometers, samples and two examples related to the materials for energy.

  6. Widespread protein aggregation as an inherent part of aging in C. elegans.

    Directory of Open Access Journals (Sweden)

    Della C David

    Full Text Available Aberrant protein aggregation is a hallmark of many age-related diseases, yet little is known about whether proteins aggregate with age in a non-disease setting. Using a systematic proteomics approach, we identified several hundred proteins that become more insoluble with age in the multicellular organism Caenorhabditis elegans. These proteins are predicted to be significantly enriched in beta-sheets, which promote disease protein aggregation. Strikingly, these insoluble proteins are highly over-represented in aggregates found in human neurodegeneration. We examined several of these proteins in vivo and confirmed their propensity to aggregate with age. Different proteins aggregated in different tissues and cellular compartments. Protein insolubility and aggregation were significantly delayed or even halted by reduced insulin/IGF-1-signaling, which also slows aging. We found a significant overlap between proteins that become insoluble and proteins that influence lifespan and/or polyglutamine-repeat aggregation. Moreover, overexpressing one aggregating protein enhanced polyglutamine-repeat pathology. Together our findings indicate that widespread protein insolubility and aggregation is an inherent part of aging and that it may influence both lifespan and neurodegenerative disease.

  7. Compact All Solid State Oceanic Inherent Optical Property Sensor, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Light propagation in the sea and the consequent remote sensing signals seen by aircraft and spacecraft is fundamentally governed by the inherent optical properties...

  8. Probabilities of inherent shutdown of unprotected events in innovative liquid metal reactors

    International Nuclear Information System (INIS)

    Mueller, C.J.; Wade, D.C.

    1988-01-01

    The uncertainty in predicting the effectiveness of inherent shutdown in innovative liquid metal cooled reactors with metallic fuel results from three broad contributing areas of uncertainty: (1) the inability to exactly predict the frequency of ATWS events with potential to challenge the safety systems and require inherent shutdown; (2) the approximation of representing all such events by a selected set of ''generic scenarios''; and (3) the inability to exactly calculate the core response to the selected generic scenarios. This paper discusses the work being done to address each of these contributing areas, identifies the design and research approaches being used at Argonne National Laboratory to reducing the key contributions to uncertainties in inherent shutdown, and presents results. The conditional probabilities (given ATWS initiation) of achieving temperatures capable of defeating inherent shutdown are shown to range from /approximately/0.1% to negligible for current designs

  9. Progress on PRISM, an inherently safe, economic, and testable advanced liquid metal reactor

    International Nuclear Information System (INIS)

    Tippets, F.E.; Salerno, L.N.; Boardman, C.E.; Kwant, W.; Murata, R.E.; Snyder, C.R.

    1987-01-01

    This paper reports progress on the design of PRISM (Power Reactor Inherently Safe Module) under the DOE-sponsored innovative reactor program now in its third year at General Electric. The purpose of this program is to develop a design for an inherently safe, reliable, and marketable liquid metal fast reactor power plant. The PRISM design approach includes the following key elements: Compact sodium-cooled pool-type reactor modules that are sized to enable factory fabrication, economical shipment to inland as well as water-side sites, and economical full-scale prototype testing for design certification; Nuclear safety-related envelope limited to the reactor modules and their service systems; Inherent, passive shutdown heat removal for loss-of-cooling events; Inherent, passive reactivity shutdown for failure-to-scram events

  10. Quantification of Inherent Respirable Dust Generation Potential (IRDGP) of South African Coals

    CSIR Research Space (South Africa)

    Phillips, H

    2003-08-01

    Full Text Available Advisory Committee Project Summary Project Title: Inherent Respirable Dust Generation Potential (IRDGP) of South African Coals-SIM020604 Author(s): H.R.Phillips and B. K. Belle Agency: University of Witwatersrand Report Date: July2003... Related Projects: Health 607, Sim 02-06-03 Category: Occupational Health Applied Research Occupational Hygiene Summary Project SIM020604 was formulated to determine the Inherent Respirable Dust Generation Potential (IRDGP) of various South...

  11. Novel OSNR Monitoring Technique in Dense WDM Systems using Inherently Generated CW Monitoring Channels

    DEFF Research Database (Denmark)

    Petersen, Martin Nordal

    2007-01-01

    We present a simple, yet effective OSNR monitoring technique based on an inherent effect in the optical modulator. Highly accurate OSNR monitoring is demonstrated in a 40 Gb/s dense WDM system with 50 GHz channel spacing.......We present a simple, yet effective OSNR monitoring technique based on an inherent effect in the optical modulator. Highly accurate OSNR monitoring is demonstrated in a 40 Gb/s dense WDM system with 50 GHz channel spacing....

  12. Guided and Unguided Student Reflections

    OpenAIRE

    Matheson, Amanda; Wood, Laura; Franklin, Scott V.

    2017-01-01

    Self-reflection is important metacognitive skill, enabling students to build coherence into their learning and embed content in a broader context. While various pedagogical techniques exist to encourage student reflection, little research has examined the differences between formally guided, partially guided and unguided reflections. This study focuses on student responses to online Guided Reflection Forms (GRFs) from students in a first-semester non-physics class and, separately, a sophomore...

  13. A real-life example of choosing an inherently safer process option

    International Nuclear Information System (INIS)

    Study, Karen

    2007-01-01

    While choosing an inherently safer alternative may seem straightforward, sometimes what seems to be the most obvious alternative may not provide the best risk reduction. The process designer must maintain a broad perspective to be able to recognize all potential hazards when evaluating design options. All aspects of operation such as start-up, shut-down, utility failure, as well as normal operation should be considered. Choosing the inherently safer option is best accomplished early in the option selection phase of a project; however, recycle back to the option selection phase may be needed if an option is not thoroughly evaluated early in the process. In this paper, a project to supply ammonia to a catalytic reactor will be reviewed. During the course of the project, an 'inherently safer' alternative was selected and later discarded due to issues uncovered during the detail design phase. The final option chosen will be compared to (1) the original design and (2) the initial 'inherently safer' alternative. The final option was inherently safer than both the original design and the initial 'inherently safer' alternative even though the design team initially believed that it would not be

  14. [THE CYTOMETRIC TECHNIQUE OF BINDING OF EOSIN-5-MALEIMIDE IN DIAGNOSTIC OF INHERENT SPHEROCYTOSIS].

    Science.gov (United States)

    Kuzminova, J A; Plyasunova, S A; Jogov, V V; Smetanina, N S

    2016-03-01

    The laboratory diagnostic of inherent spherocytosis is based on detection of spherocytes in peripheral blood, decreasing of index of sphericity, decreasing of osmotic resistance of erythrocytes. The new test of diagnostic of hereditary spherocytosis build on molecular defect was developed on the basis of binding extracellular fragments of protein of band 3 with eosin-5-maleimide (EMA-test). The study was carried out to implement comparative analysis of sensitivity and specificity of techniques applied to diagnose inherent spherocytosis. The sampling of 94 patients with various forms of anemias was analyzed All patients were applied complex clinical laboratory examination including analysis of osmotic resistance of erythrocytes, erythrocytometry and EMA-test as specific techniques of diagnostic of inherent spherocytosis. In 51 out of 94 patients (54%) decreasing of values of EMA-test was detected and in 47 patients diagnosis of inherent spherocytosis was confirmed. The standard values of EMA-test were established in 43 patients (46%) and 12 patients out of them with established diagnosis of inherent spherocytosis. Therefore, sensitivity of EMA-test made up to 79% and specificity - 80%. The most sensitive techniques of diagnostic remain osmotic resistance of erythrocytes (91%) and index of sphericity (up to 96%). But the highest specificity in this respect has EMA-test (80%). Nowadays, none of implemented techniques of diagnostic of inherent spherocytosis can be applied as a universal one. The implementation of complex examination is needed for proper diagnostic of disease.

  15. Development of quantitative goals for inherent safety feature design and licensing

    International Nuclear Information System (INIS)

    Kastenberg, W.E.; Apostolakis, G.; Dhir, V.K.; Okrent, D.

    1987-01-01

    There is now considerable interest in the development of advanced fast reactors whose major focus is inherent safety. The achievement of inherent safety can be viewed from several aspects. In the Integral Fast Reactor Concept the approach is to utilize the intrinsic characteristics of pool-type liquid metal fast breeder reactors (LMFBRs) and the properties of metal fuels to integrate a high degree of inherent safety into the design. The PRISM and SAFR concepts focus on other inherent safety features. The reactors discussed above represent a radical departure from existing LWR designs as well as previous LMFBR designs (e.g., CRBRP) which are based, for the most part, on the General Design Criteria found in 10CFR50 Appendix. In view of these parallel developments (advanced reactors exploiting inherent safety and the use of quantitative goals to augment licensing), there appears to be a need to perform research on the development of methods for designing, assessing, and licensing inherent safety features in advanced reactors. The objectives of such research are outlined

  16. Assessing phosphatidylethanol (PEth) levels reflecting different drinking habits in comparison to the alcohol use disorders identification test - C (AUDIT-C).

    Science.gov (United States)

    Schröck, Alexandra; Wurst, Friedrich M; Thon, Natasha; Weinmann, Wolfgang

    2017-09-01

    In addition to monitoring problematic or harmful alcohol consumption, drinking experiments indicated the potential of phosphatidylethanols (PEth) in abstinence monitoring. To date, no profound evaluation of thresholds for the differentiation of abstinence from moderate drinking and for detection of excessive consumption based on PEth homologues exists. Investigations with a large group of healthy volunteers (n=300) were performed to establish PEth reference values reflecting different drinking habits. Blood samples were analyzed for PEth 16:0/18:1 and 16:0/18:2 by online-SPE-LC-MS/MS method. Results were compared to AUDIT-C questionnaires, to the amounts of alcohol consumed during the two-weeks prior to blood sampling, and were statistically evaluated. PEth concentrations were significantly correlated with self-reported alcohol consumption (r>0.69) and with AUDIT-C scores (r>0.65). 4.0% of 300 volunteers reported abstinence (AUDIT-C score: 0), no PEth was detectable in their blood. PEth 16:0/18:1 concentrations below the limit of detection of 10.0ng/mL match with abstinence and light drinking habits (≤10g pure alcohol/day). However, some volunteers classified as "excessive alcohol consumers" had negative PEth results. In the group of volunteers classified as "moderate drinkers" (AUDIT-C score: 1-3 (women) and 1-4 (men)), 95% of the test persons had PEth 16:0/18:1 ranging from not detected to 112ng/mL, and PEth 16:0/18:2 ranging from not detected to 67.0ng/mL. Combination of self-reported alcohol consumption and AUDIT-C score showed that negative PEth results match with abstinence or light drinking. Moderate alcohol consumption resulted in PEth 16:0/18:1 from 0 to 112ng/mL and for PEth 16:0/18:2 ranged from 0 to 67.0ng/mL. Higher PEth concentrations indicated excessive alcohol consumption. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Reflected Glory

    Science.gov (United States)

    2011-02-01

    The nebula Messier 78 takes centre stage in this image taken with the Wide Field Imager on the MPG/ESO 2.2-metre telescope at the La Silla Observatory in Chile, while the stars powering the bright display take a backseat. The brilliant starlight ricochets off dust particles in the nebula, illuminating it with scattered blue light. Igor Chekalin was the overall winner of ESO's Hidden Treasures 2010 astrophotography competition with his image of this stunning object. Messier 78 is a fine example of a reflection nebula. The ultraviolet radiation from the stars that illuminate it is not intense enough to ionise the gas to make it glow - its dust particles simply reflect the starlight that falls on them. Despite this, Messier 78 can easily be observed with a small telescope, being one of the brightest reflection nebulae in the sky. It lies about 1350 light-years away in the constellation of Orion (The Hunter) and can be found northeast of the easternmost star of Orion's belt. This new image of Messier 78 from the MPG/ESO 2.2-metre telescope at the La Silla Observatory is based on data selected by Igor Chekalin in his winning entry to the Hidden Treasures competition [1]. The pale blue tint seen in the nebula in this picture is an accurate representation of its dominant colour. Blue hues are commonly seen in reflection nebulae because of the way the starlight is scattered by the tiny dust particles that they contain: the shorter wavelength of blue light is scattered more efficiently than the longer wavelength red light. This image contains many other striking features apart from the glowing nebula. A thick band of obscuring dust stretches across the image from the upper left to the lower right, blocking the light from background stars. In the bottom right corner, many curious pink structures are also visible, which are created by jets of material being ejected from stars that have recently formed and are still buried deep in dust clouds. Two bright stars, HD 38563A and

  18. But do you think I'm cool? Developmental differences in striatal recruitment during direct and reflected social self-evaluations.

    Science.gov (United States)

    Jankowski, Kathryn F; Moore, William E; Merchant, Junaid S; Kahn, Lauren E; Pfeifer, Jennifer H

    2014-04-01

    The current fMRI study investigates the neural foundations of evaluating oneself and others during early adolescence and young adulthood. Eighteen early adolescents (ages 11-14, M=12.6) and 19 young adults (ages 22-31, M=25.6) evaluated whether academic, physical, and social traits described themselves directly (direct self-evaluations), described their best friend directly (direct other-evaluations), described themselves from their best friend's perspective (reflected self-evaluations), or in general could change over time (control malleability-evaluations). Compared to control evaluations, both adolescents and adults recruited cortical midline structures during direct and reflected self-evaluations, as well as during direct other-evaluations, converging with previous research. However, unique to this study was a significant three-way interaction between age group, evaluative perspective, and domain within bilateral ventral striatum. Region of interest analyses demonstrated a significant evaluative perspective by domain interaction within the adolescent sample only. Adolescents recruited greatest bilateral ventral striatum during reflected social self-evaluations, which was positively correlated with age and pubertal development. These findings suggest that reflected social self-evaluations, made from the inferred perspective of a close peer, may be especially self-relevant, salient, or rewarding to adolescent self-processing--particularly during the progression through adolescence - and this feature persists into adulthood. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  19. Underwater Inherent Optical Properties Estimation Using a Depth Aided Deep Neural Network

    Directory of Open Access Journals (Sweden)

    Zhibin Yu

    2017-01-01

    Full Text Available Underwater inherent optical properties (IOPs are the fundamental clues to many research fields such as marine optics, marine biology, and underwater vision. Currently, beam transmissometers and optical sensors are considered as the ideal IOPs measuring methods. But these methods are inflexible and expensive to be deployed. To overcome this problem, we aim to develop a novel measuring method using only a single underwater image with the help of deep artificial neural network. The power of artificial neural network has been proved in image processing and computer vision fields with deep learning technology. However, image-based IOPs estimation is a quite different and challenging task. Unlike the traditional applications such as image classification or localization, IOP estimation looks at the transparency of the water between the camera and the target objects to estimate multiple optical properties simultaneously. In this paper, we propose a novel Depth Aided (DA deep neural network structure for IOPs estimation based on a single RGB image that is even noisy. The imaging depth information is considered as an aided input to help our model make better decision.

  20. Distinct Short-Range Order Is Inherent to Small Amorphous Calcium Carbonate Clusters (<2 nm)

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Shengtong [Physical Chemistry, University of Konstanz, Universitätsstrasse 10 78457 Konstanz Germany; School of Chemical Engineering, State Key Laboratory of Chemical Engineering, Shanghai Key Laboratory of Multiphase Materials Chemical Engineering, East China University of Science and Technology, 130 Meilong Road Shanghai 200237 P.R. China; Chevrier, Daniel M. [Department of Chemistry and Institute for Research in Materials, Dalhousie University, Halifax Nova Scotia B3H 4R2 Canada; Zhang, Peng [Department of Chemistry and Institute for Research in Materials, Dalhousie University, Halifax Nova Scotia B3H 4R2 Canada; Gebauer, Denis [Physical Chemistry, University of Konstanz, Universitätsstrasse 10 78457 Konstanz Germany; Cölfen, Helmut [Physical Chemistry, University of Konstanz, Universitätsstrasse 10 78457 Konstanz Germany

    2016-09-09

    Amorphous intermediate phases are vital precursors in the crystallization of many biogenic minerals. While inherent short-range orders have been found in amorphous calcium carbonates (ACCs) relating to different crystalline forms, it has never been clarified experimentally whether such orders already exist in very small clusters less than 2 nm in size. Here, we studied the stability and structure of 10,12-pentacosadiynoic acid (PCDA) protected ACC clusters with a core size of ca. 1.4 nm consisting of only seven CaCO3 units. Ligand concentration and structure are shown to be key factors in stabilizing the ACC clusters. More importantly, even in such small CaCO3 entities, a proto-calcite short-range order can be identified but with a relatively high degree of disorder that arises from the very small size of the CaCO3 core. Our findings support the notion of a structural link between prenucleation clusters, amorphous intermediates, and final crystalline polymorphs, which appears central to the understanding of polymorph selection.

  1. An analytic framework for developing inherently-manufacturable pop-up laminate devices

    International Nuclear Information System (INIS)

    Aukes, Daniel M; Goldberg, Benjamin; Wood, Robert J; Cutkosky, Mark R

    2014-01-01

    Spurred by advances in manufacturing technologies developed around layered manufacturing technologies such as PC-MEMS, SCM, and printable robotics, we propose a new analytic framework for capturing the geometry of folded composite laminate devices and the mechanical processes used to manufacture them. These processes can be represented by combining a small set of geometric operations which are general enough to encompass many different manufacturing paradigms. Furthermore, such a formulation permits one to construct a variety of geometric tools which can be used to analyze common manufacturability concepts, such as tool access, part removability, and device support. In order to increase the speed of development, reduce the occurrence of manufacturing problems inherent with current design methods, and reduce the level of expertise required to develop new devices, the framework has been implemented in a new design tool called popupCAD, which is suited for the design and development of complex folded laminate devices. We conclude with a demonstration of utility of the tools by creating a folded leg mechanism. (paper)

  2. Generalized Ocean Color Inversion Model for Retrieving Marine Inherent Optical Properties

    Science.gov (United States)

    Werdell, P. Jeremy; Franz, Bryan A.; Bailey, Sean W.; Feldman, Gene C.; Boss, Emmanuel; Brando, Vittorio E.; Dowell, Mark; Hirata, Takafumi; Lavender, Samantha J.; Lee, ZhongPing; hide

    2013-01-01

    Ocean color measured from satellites provides daily, global estimates of marine inherent optical properties (IOPs). Semi-analytical algorithms (SAAs) provide one mechanism for inverting the color of the water observed by the satellite into IOPs. While numerous SAAs exist, most are similarly constructed and few are appropriately parameterized for all water masses for all seasons. To initiate community-wide discussion of these limitations, NASA organized two workshops that deconstructed SAAs to identify similarities and uniqueness and to progress toward consensus on a unified SAA. This effort resulted in the development of the generalized IOP (GIOP) model software that allows for the construction of different SAAs at runtime by selection from an assortment of model parameterizations. As such, GIOP permits isolation and evaluation of specific modeling assumptions, construction of SAAs, development of regionally tuned SAAs, and execution of ensemble inversion modeling. Working groups associated with the workshops proposed a preliminary default configuration for GIOP (GIOP-DC), with alternative model parameterizations and features defined for subsequent evaluation. In this paper, we: (1) describe the theoretical basis of GIOP; (2) present GIOP-DC and verify its comparable performance to other popular SAAs using both in situ and synthetic data sets; and, (3) quantify the sensitivities of their output to their parameterization. We use the latter to develop a hierarchical sensitivity of SAAs to various model parameterizations, to identify components of SAAs that merit focus in future research, and to provide material for discussion on algorithm uncertainties and future ensemble applications.

  3. Improvement of inherent safety features in CSR (Coupled Spectrum Reactor) for treating MA

    International Nuclear Information System (INIS)

    Aziz, F.; Kitamoto, Asashi.

    1996-01-01

    Burning and/or transmutation (B/T) of MA is proposed here using a CSR (Coupled Spectrum Reactor) concept. CSR was based on a modified conventional 1150 MWe-PWR system, and consisted of two core regions for thermal and fast neutrons, respectively. The B/T fuel used was supposed such that MA discharged from 1 GWe-LWR were mixed homogeneously in LWR fuel. The geometry of B/T fuel in the outer region was left the same with that of PWR, while in the inner region the B/T fuel was arranged in a tight-lattice geometry that allowed a higher fuel to coolant volume ratio, (V m /V f ). In order to improve its inherent safety features, several cases of CSR were studied and compared, each case used different fuel type in the inner region. The result of the calculations showed that safety features can be improved by using composite fuel of ( 235 U-Pu- 238 U) in the inner region. The equilibrium of main isotopes in CSR can be achieved after about 5 recycle stages. This study also showed that the CSR can burn and transmute MA up to 808 kg/stage in a single reactor operated with a reactivity swing of 2.8 % Δk/kk'. (author)

  4. Underwater Inherent Optical Properties Estimation Using a Depth Aided Deep Neural Network.

    Science.gov (United States)

    Yu, Zhibin; Wang, Yubo; Zheng, Bing; Zheng, Haiyong; Wang, Nan; Gu, Zhaorui

    2017-01-01

    Underwater inherent optical properties (IOPs) are the fundamental clues to many research fields such as marine optics, marine biology, and underwater vision. Currently, beam transmissometers and optical sensors are considered as the ideal IOPs measuring methods. But these methods are inflexible and expensive to be deployed. To overcome this problem, we aim to develop a novel measuring method using only a single underwater image with the help of deep artificial neural network. The power of artificial neural network has been proved in image processing and computer vision fields with deep learning technology. However, image-based IOPs estimation is a quite different and challenging task. Unlike the traditional applications such as image classification or localization, IOP estimation looks at the transparency of the water between the camera and the target objects to estimate multiple optical properties simultaneously. In this paper, we propose a novel Depth Aided (DA) deep neural network structure for IOPs estimation based on a single RGB image that is even noisy. The imaging depth information is considered as an aided input to help our model make better decision.

  5. A Reflectance Model for Relatively Clear and Turbid Waters

    Directory of Open Access Journals (Sweden)

    S. P. Tiwari

    2013-02-01

    Full Text Available Accurate modeling of spectral remote sensing reflectance (Rrs is of great interest for ocean colour studies in highly turbid and relatively clear waters. In this work a semianalytical model that simulates the spectral curves of remote sensing reflectance of these waters is developed based on the inherent optical properties (IOPs and f and Q factors. For accommodating differences in the optical properties of the water and accounting for their directional variations, IOPs and f and Q factors are derived as a function of phytoplankton pigments, suspended sediments and solar zenith angle. Results of this model are compared with in-situ bio-optical data collected at 83 stations encompassing highly turbid/relatively cleared waters of the South Sea of Korea. Measured and modeled remote sensing reflectances agree favorably in both magnitude and spectral shape, with considerably low errors (mean relative error MRE -0.0327; root mean square error RMSE 0.205, bias -0.0727 and slope 1.15 and correlation coefficient R2 0.74. These results suggest that the new model has the ability to reproduce measured reflectance values and has potentially profound implications for remote sensing of complex waters in this region.

  6. Is the inherent potential of maize roots efficient for soil phosphorus acquisition?

    Science.gov (United States)

    Deng, Yan; Chen, Keru; Teng, Wan; Zhan, Ai; Tong, Yiping; Feng, Gu; Cui, Zhenling; Zhang, Fusuo; Chen, Xinping

    2014-01-01

    Sustainable agriculture requires improved phosphorus (P) management to reduce the overreliance on P fertilization. Despite intensive research of root adaptive mechanisms for improving P acquisition, the inherent potential of roots for efficient P acquisition remains unfulfilled, especially in intensive agriculture, while current P management generally focuses on agronomic and environmental concerns. Here, we investigated how levels of soil P affect the inherent potential of maize (Zea mays L.) roots to obtain P from soil. Responses of root morphology, arbuscular mycorrhizal colonization, and phosphate transporters were characterized and related to agronomic traits in pot and field experiments with soil P supply from deficiency to excess. Critical soil Olsen-P level for maize growth approximated 3.2 mg kg(-1), and the threshold indicating a significant environmental risk was about 15 mg kg(-1), which represented the lower and upper levels of soil P recommended in current P management. However, most root adaptations involved with P acquisition were triggered when soil Olsen-P was below 10 mg kg(-1), indicating a threshold for maximum root inherent potential. Therefore, to maintain efficient inherent potential of roots for P acquisition, we suggest that the target upper level of soil P in intensive agriculture should be reduced from the environmental risk threshold to the point maximizing the inherent potential of roots.

  7. Is the inherent potential of maize roots efficient for soil phosphorus acquisition?

    Directory of Open Access Journals (Sweden)

    Yan Deng

    Full Text Available Sustainable agriculture requires improved phosphorus (P management to reduce the overreliance on P fertilization. Despite intensive research of root adaptive mechanisms for improving P acquisition, the inherent potential of roots for efficient P acquisition remains unfulfilled, especially in intensive agriculture, while current P management generally focuses on agronomic and environmental concerns. Here, we investigated how levels of soil P affect the inherent potential of maize (Zea mays L. roots to obtain P from soil. Responses of root morphology, arbuscular mycorrhizal colonization, and phosphate transporters were characterized and related to agronomic traits in pot and field experiments with soil P supply from deficiency to excess. Critical soil Olsen-P level for maize growth approximated 3.2 mg kg(-1, and the threshold indicating a significant environmental risk was about 15 mg kg(-1, which represented the lower and upper levels of soil P recommended in current P management. However, most root adaptations involved with P acquisition were triggered when soil Olsen-P was below 10 mg kg(-1, indicating a threshold for maximum root inherent potential. Therefore, to maintain efficient inherent potential of roots for P acquisition, we suggest that the target upper level of soil P in intensive agriculture should be reduced from the environmental risk threshold to the point maximizing the inherent potential of roots.

  8. Improving Coastal Ocean Color Validation Capabilities through Application of Inherent Optical Properties (IOPs)

    Science.gov (United States)

    Mannino, Antonio

    2008-01-01

    Understanding how the different components of seawater alter the path of incident sunlight through scattering and absorption is essential to using remotely sensed ocean color observations effectively. This is particularly apropos in coastal waters where the different optically significant components (phytoplankton, detrital material, inorganic minerals, etc.) vary widely in concentration, often independently from one another. Inherent Optical Properties (IOPs) form the link between these biogeochemical constituents and the Apparent Optical Properties (AOPs). understanding this interrelationship is at the heart of successfully carrying out inversions of satellite-measured radiance to biogeochemical properties. While sufficient covariation of seawater constituents in case I waters typically allows empirical algorithms connecting AOPs and biogeochemical parameters to behave well, these empirical algorithms normally do not hold for case I1 regimes (Carder et al. 2003). Validation in the context of ocean color remote sensing refers to in-situ measurements used to verify or characterize algorithm products or any assumption used as input to an algorithm. In this project, validation capabilities are considered those measurement capabilities, techniques, methods, models, etc. that allow effective validation. Enhancing current validation capabilities by incorporating state-of-the-art IOP measurements and optical models is the purpose of this work. Involved in this pursuit is improving core IOP measurement capabilities (spectral, angular, spatio-temporal resolutions), improving our understanding of the behavior of analytical AOP-IOP approximations in complex coastal waters, and improving the spatial and temporal resolution of biogeochemical data for validation by applying biogeochemical-IOP inversion models so that these parameters can be computed from real-time IOP sensors with high sampling rates. Research cruises supported by this project provides for collection and

  9. Impact of calcification state on the inherent optical properties of Emiliania huxleyi coccoliths and coccolithophores

    Science.gov (United States)

    Bi, Lei; Yang, Ping

    2015-04-01

    Understanding the inherent optical properties (IOPs) of coccoliths and coccolithophores is important in oceanic radiative transfer simulations and remote sensing implementations. In this study, the invariant imbedding T-matrix method (II-TM) is employed to investigate the IOPs of coccoliths and coccolithophores. The Emiliania huxleyi (Ehux) coccolith and coccolithophore models are built based on observed biometric parameters including the eccentricity, the number of slits, and the rim width of detached coccoliths. The calcification state that specifies the amount of calcium of a single coccolith is critical in the determination of the size-volume/mass relationship (note, the volume/mass of coccoltihs at different calcification states are different although the diameters are the same). The present results show that the calcification state, namely, under-calcification, normal-calcification, or over-calcification, significantly influences the backscattering cross section and the phase matrix. Furthermore, the linear depolarization ratio of the light scattered by coccoliths is sensitive to the degree of calcification, and provides a potentially valuable parameter for interpreting oceanic remote sensing data. The phase function of an ensemble of randomly oriented coccolithophores has a similar pattern to that of individual coccoliths, but the forward scattering is dominant in the coccolithophores due to the large geometric cross sections. The linear depolarization ratio associated with coccolithophores is found to be larger than that for coccoliths as polarization is more sensitive to multiple scattering than the phase function. The simulated coccolithophore phase matrix numerical results are compared with laboratory measurements. For scattering angles larger than 100°, an increase of the phase function with respect to the scattering angle is confirmed based on the present coccolithophore model while the spherical approximation fails.

  10. Impact of calcification state on the inherent optical properties of Emiliania huxleyi coccoliths and coccolithophores

    International Nuclear Information System (INIS)

    Bi, Lei; Yang, Ping

    2015-01-01

    Understanding the inherent optical properties (IOPs) of coccoliths and coccolithophores is important in oceanic radiative transfer simulations and remote sensing implementations. In this study, the invariant imbedding T-matrix method (II-TM) is employed to investigate the IOPs of coccoliths and coccolithophores. The Emiliania huxleyi (Ehux) coccolith and coccolithophore models are built based on observed biometric parameters including the eccentricity, the number of slits, and the rim width of detached coccoliths. The calcification state that specifies the amount of calcium of a single coccolith is critical in the determination of the size–volume/mass relationship (note, the volume/mass of coccoltihs at different calcification states are different although the diameters are the same). The present results show that the calcification state, namely, under-calcification, normal-calcification, or over-calcification, significantly influences the backscattering cross section and the phase matrix. Furthermore, the linear depolarization ratio of the light scattered by coccoliths is sensitive to the degree of calcification, and provides a potentially valuable parameter for interpreting oceanic remote sensing data. The phase function of an ensemble of randomly oriented coccolithophores has a similar pattern to that of individual coccoliths, but the forward scattering is dominant in the coccolithophores due to the large geometric cross sections. The linear depolarization ratio associated with coccolithophores is found to be larger than that for coccoliths as polarization is more sensitive to multiple scattering than the phase function. The simulated coccolithophore phase matrix numerical results are compared with laboratory measurements. For scattering angles larger than 100°, an increase of the phase function with respect to the scattering angle is confirmed based on the present coccolithophore model while the spherical approximation fails. - Highlights: • Realistic

  11. Reflection on Political Representation

    DEFF Research Database (Denmark)

    Kusche, Isabel

    2017-01-01

    This article compares how Members of Parliament in the United Kingdom and Ireland reflect on constituency service as an aspect of political representation. It differs from existing research on the constituency role of MPs in two regards. First, it approaches the question from a sociological viewp...

  12. Results and implications of the EBR-II inherent safety demonstration tests

    International Nuclear Information System (INIS)

    Planchon, H.P.; Golden, G.H.; Sackett, J.I.; Mohr, D.; Chang, L.K.; Feldman, E.E.; Betten, P.R.

    1987-01-01

    On April 3, 1986 two milestone tests were conducted in Experimental Breeder Reactor-2 (EBR-II). The first test was a loss of flow without scram and the second was a loss of heat sink without scram. Both tests were initiated from 100% power and in both tests the reactor was shut down by natural processes, principally thermal expansion, without automatic scram, operator intervention or the help of special in-core devices. The temperature transients during the tests were mild, as predicted, and there was no damage to the core or reactor plant structures. In a general sense, therefore, the tests plus supporting analysis demonstrated the feasibility of inherent passive shutdown for undercooling accidents in metal-fueled LMRs. The results provide a technical basis for future experiments in EBR-II to demonstrate inherent safety for overpower accidents and provide data for validation of computer codes used for design and safety analysis of inherently safe reactor plants

  13. Thoughts on Reflection (Editorial

    Directory of Open Access Journals (Sweden)

    Denise Koufogiannakis

    2010-06-01

    Evidence in Practice section uses a standardized format enabling practitioners to share their experience of integrating research evidence into their practice. The final section of these brief articles asks the writers to reflect on their experience. Although it is not research, the individual reflection allies with what Schön (1983 called “reflection on action” and such reflections over time form a practical, tacit knowledge that we use to inform our work. Within this section of the journal, we hope readers will become more aware of how different types of evidence can be integrated into real‐world decision making. Not everything requires a full blown research study, and this section allows readers to see what other practitioners are doing, and in turn it should enable them to reflect upon what they are doing in their own practice. Being aware of situations where things may or may not have worked, and reflecting on the reasons why, brings together our sense of critical thought and practical experience that go a long way in filling the “librarian observed” and “professional judgements” parts of the EBLIP definition (Booth and Brice 2004. Acquiring professional knowledge does not end when we complete a graduate program, or have a certain number of years experience under our belts. It needs to be continually and consciously cultivated via reflection on our practice, our research, and simply what works and why. Research knowledge only takes us so far. People often ask me, “What do I do when there is no evidence? Or when the research evidence is weak?” Does this stop us from moving ahead? No. A decision still needs to be made. Evidence based practice is not only about acting when there is good evidence. Enhancing our professional judgments via a career built on analytical reflection, will provide knowledge that goes a long way towards making difficult decisions a little bit easier; even (or perhaps, especially in the cases when there is already a large body of

  14. Deliberate practice theory: perceived relevance, effort, and inherent enjoyment of music practice: study II.

    Science.gov (United States)

    Hyllegard, Randy; Bories, Tamara L

    2009-10-01

    This study, based on the theory of deliberate practice, examined the practice relevance, effort, and inherent enjoyment aspects of the theory. 25 college undergraduates practiced playing a melody on an electronic keyboard for three 20-min. practice sessions. Following each session, the perceived relevance of the practice for improving performance of the melody, the effort needed to learn the melody, and the inherent enjoyment of the practice were each rated on 10-point scales. Findings were consistent with theory and similar to previous studies also involving music practice and other tasks.

  15. Impacts of reactivity feedback uncertainties on inherent shutdown in innovative designs

    International Nuclear Information System (INIS)

    Mueller, C.J.

    1986-01-01

    The concept of inherent shutdown is emphasized in the approach to the design of innovative, small pool-type liquid-metal reactors (LMRs). This paper reports an evaluation of reactivity feedback uncertainties used in the analyses of anticipated transients without scram for innovative LMRs, and the associated impacts on safety margins and inherent shutdown success probabilities on unprotected loss-of-flow (LOF) events. It then assesses the ultimate importance of these uncertainties on LOF and transient overpower events in evolving metal and oxide innovative designs

  16. Inherent safe design of advanced high temperature reactors - concepts for future nuclear power plants

    International Nuclear Information System (INIS)

    Hodzic, A.; Kugeler, K.

    1997-01-01

    This paper discusses the applicable solutions for a commercial size High Temperature Reactor (HTR) with inherent safety features. It describes the possible realization using an advanced concept which combines newly proposed design characteristics with some well known and proven HTR inherent safety features. The use of the HTR technology offers the conceivably best solution to meet the legal criteria, recently stated in Germany, for the future reactor generation. Both systems, block and pebble bed ,reactor, could be under certain design conditions self regulating in terms of core nuclear heat, mechanical stability and the environmental transfer. 23 refs., 7 figs

  17. Probabilities of inherent shutdown of unprotected events in innovative liquid metal reactors

    International Nuclear Information System (INIS)

    Mueller, C.J.

    1987-01-01

    The uncertainty in predicting the effectiveness of inherent shutdown (ISD) in innovative designs results from three broad contributing areas of uncertainty: (1) the inability to exactly predict the frequency of ATWS events with potential to challenge the safety systems and require ISD; (2) the approximation of representing all such ATWS events by a selected set of ''generic scenarios''; and (3) the inability to exactly calculate the core response to the selected generic scenarios. In this summary, the methodology and associated results of work used to establish probabilities of failure of inherent shutdown of innovative LMRs to the unprotected loss-of-flow (LOF) accident are discussed

  18. Government can regulate food advertising to children because cognitive research shows that it is inherently misleading.

    Science.gov (United States)

    Graff, Samantha; Kunkel, Dale; Mermin, Seth E

    2012-02-01

    The childhood obesity crisis has prompted repeated calls for government action to curb the marketing of unhealthy food to children. Food and entertainment industry groups have asserted that the First Amendment prohibits such regulation. However, case law establishes that the First Amendment does not protect "inherently misleading" commercial speech. Cognitive research indicates that young children cannot effectively recognize the persuasive intent of advertising or apply the critical evaluation required to comprehend commercial messages. Given this combination--that government can prohibit "inherently misleading" advertising and that children cannot adequately understand commercial messages--advertising to children younger than age twelve should be considered beyond the scope of constitutional protection.

  19. Inherent Limitations in Mid-Wave and Long-Wave-IR Upconversion Detector

    DEFF Research Database (Denmark)

    Barh, Ajanta; Tseng, Yu-Pei; Pedersen, Christian

    2017-01-01

    Inherent limitations in terms of optical losses, selection of nonlinear crystal(s), detection efficiency and pumping conditions in mid-wave (3-5 µm) and long-wave (8-12 µm) infrared frequency upconversion modules are investigated in this paper.......Inherent limitations in terms of optical losses, selection of nonlinear crystal(s), detection efficiency and pumping conditions in mid-wave (3-5 µm) and long-wave (8-12 µm) infrared frequency upconversion modules are investigated in this paper....

  20. Impacts of reactivity feedback uncertainties on inherent shutdown in innovative designs

    International Nuclear Information System (INIS)

    Mueller, C.J.

    1986-01-01

    The concept of ''inherent shutdown'' is emphasized in the approach to the design of innovative, small pool-type liquid metal reactors (LMRs). This paper reports an evaluation of reactivity feedback uncertainties used in the analyses of anticipated transients without scram (ATWS) for innovative LMRs, and the associated impacts on safety margins and inherent shutdown success probabilities on unprotected loss-of-flow (LOF) events. It then assesses the ultimate importance of these uncertainties on LOF and transient overpower (TOP) events in evolving metal and oxide innovative designs

  1. A hybrid model for mapping relative differences in belowground biomass and root: Shoot ratios using spectral reflectance, foliar N and plant biophysical data within coastal marsh

    Science.gov (United States)

    Jessica L. O'Connell,; Byrd, Kristin B.; Maggi Kelly,

    2015-01-01

    Broad-scale estimates of belowground biomass are needed to understand wetland resiliency and C and N cycling, but these estimates are difficult to obtain because root:shoot ratios vary considerably both within and between species. We used remotely-sensed estimates of two aboveground plant characteristics, aboveground biomass and % foliar N to explore biomass allocation in low diversity freshwater impounded peatlands (Sacramento-San Joaquin River Delta, CA, USA). We developed a hybrid modeling approach to relate remotely-sensed estimates of % foliar N (a surrogate for environmental N and plant available nutrients) and aboveground biomass to field-measured belowground biomass for species specific and mixed species models. We estimated up to 90% of variation in foliar N concentration using partial least squares (PLS) regression of full-spectrum field spectrometer reflectance data. Landsat 7 reflectance data explained up to 70% of % foliar N and 67% of aboveground biomass. Spectrally estimated foliar N or aboveground biomass had negative relationships with belowground biomass and root:shoot ratio in both Schoenoplectus acutus and Typha, consistent with a balanced growth model, which suggests plants only allocate growth belowground when additional nutrients are necessary to support shoot development. Hybrid models explained up to 76% of variation in belowground biomass and 86% of variation in root:shoot ratio. Our modeling approach provides a method for developing maps of spatial variation in wetland belowground biomass.

  2. Measuring situational awareness and resolving inherent high-level fusion obstacles

    Science.gov (United States)

    Sudit, Moises; Stotz, Adam; Holender, Michael; Tagliaferri, William; Canarelli, Kathie

    2006-04-01

    Information Fusion Engine for Real-time Decision Making (INFERD) is a tool that was developed to supplement current graph matching techniques in Information Fusion models. Based on sensory data and a priori models, INFERD dynamically generates, evolves, and evaluates hypothesis on the current state of the environment. The a priori models developed are hierarchical in nature lending them to a multi-level Information Fusion process whose primary output provides a situational awareness of the environment of interest in the context of the models running. In this paper we look at INFERD's multi-level fusion approach and provide insight on the inherent problems such as fragmentation in the approach and the research being undertaken to mitigate those deficiencies. Due to the large variance of data in disparate environments, the awareness of situations in those environments can be drastically different. To accommodate this, the INFERD framework provides support for plug-and-play fusion modules which can be developed specifically for domains of interest. However, because the models running in INFERD are graph based, some default measurements can be provided and will be discussed in the paper. Among these are a Depth measurement to determine how much danger is presented by the action taking place, a Breadth measurement to gain information regarding the scale of an attack that is currently happening, and finally a Reliability measure to tell the user the credibility of a particular hypothesis. All of these results will be demonstrated in the Cyber domain where recent research has shown to be an area that is welldefined and bounded, so that new models and algorithms can be developed and evaluated.

  3. Influence of the inherent properties of drinking water treatment residuals on their phosphorus adsorption capacities.

    Science.gov (United States)

    Bai, Leilei; Wang, Changhui; He, Liansheng; Pei, Yuansheng

    2014-12-01

    Batch experiments were conducted to investigate the phosphorus (P) adsorption and desorption on five drinking water treatment residuals (WTRs) collected from different regions in China. The physical and chemical characteristics of the five WTRs were determined. Combined with rotated principal component analysis, multiple regression analysis was used to analyze the relationship between the inherent properties of the WTRs and their P adsorption capacities. The results showed that the maximum P adsorption capacities of the five WTRs calculated using the Langmuir isotherm ranged from 4.17 to 8.20mg/g at a pH of 7 and further increased with a decrease in pH. The statistical analysis revealed that a factor related to Al and 200 mmol/L oxalate-extractable Al (Alox) accounted for 36.5% of the variations in the P adsorption. A similar portion (28.5%) was attributed to an integrated factor related to the pH, Fe, 200 mmol/L oxalate-extractable Fe (Feox), surface area and organic matter (OM) of the WTRs. However, factors related to other properties (Ca, P and 5 mmol/L oxalate-extractable Fe and Al) were rejected. In addition, the quantity of P desorption was limited and had a significant negative correlation with the (Feox+Alox) of the WTRs (p<0.05). Overall, WTRs with high contents of Alox, Feox and OM as well as large surface areas were proposed to be the best choice for P adsorption in practical applications. Copyright © 2014. Published by Elsevier B.V.

  4. Correcting Bidirectional Effects in Remote Sensing Reflectance from Coastal Waters

    Science.gov (United States)

    Stamnes, K. H.; Fan, Y.; Li, W.; Voss, K. J.; Gatebe, C. K.

    2016-02-01

    Understanding bidirectional effects including sunglint is important for GEO-CAPE for several reasons: (i) correct interpretation of ocean color data; (ii) comparing consistency of spectral radiance data derived from space observations with a single instrument for a variety of illumination and viewing conditions; (iii) merging data collected by different instruments operating simultaneously. We present a new neural network (NN) method to correct bidirectional effects in water-leaving radiance for both Case 1 and Case 2 waters. We also discuss a new BRDF and 2D sun-glint model that was validated by comparing simulated surface reflectances with Cloud Absorption Radiometer (CAR) data. Finally, we present an extension of our marine bio-optical model to the UV range that accounts for the seasonal dependence of the inherent optical properties (IOPs).

  5. High-resolution wave-theory-based ultrasound reflection imaging using the split-step fourier and globally optimized fourier finite-difference methods

    Science.gov (United States)

    Huang, Lianjie

    2013-10-29

    Methods for enhancing ultrasonic reflection imaging are taught utilizing a split-step Fourier propagator in which the reconstruction is based on recursive inward continuation of ultrasonic wavefields in the frequency-space and frequency-wave number domains. The inward continuation within each extrapolation interval consists of two steps. In the first step, a phase-shift term is applied to the data in the frequency-wave number domain for propagation in a reference medium. The second step consists of applying another phase-shift term to data in the frequency-space domain to approximately compensate for ultrasonic scattering effects of heterogeneities within the tissue being imaged (e.g., breast tissue). Results from various data input to the method indicate significant improvements are provided in both image quality and resolution.

  6. The Market for Academic Knowledge: Its Historical Emergence and Inherent Tensions

    Science.gov (United States)

    Weik, Elke

    2014-01-01

    This paper contributes to the discussion about the marketisation of universities by providing a historical perspective. Going back to the time when the market for academic knowledge emerged, I argue that it was created through incorporating a number of inherent tensions that have been, and still are, shaping its development. I show how these…

  7. Generalizing a model beyond the inherence heuristic and applying it to beliefs about objective value.

    Science.gov (United States)

    Wood, Graham

    2014-10-01

    The inherence heuristic is characterized as part of an instantiation of a more general model that describes the interaction between undeveloped intuitions, produced by System 1 heuristics, and developed beliefs, constructed by System 2 reasoning. The general model is described and illustrated by examining another instantiation of the process that constructs belief in objective moral value.

  8. Thermosetting resins with high fractions of free volume and inherently low dielectric constants.

    Science.gov (United States)

    Lin, Liang-Kai; Hu, Chien-Chieh; Su, Wen-Chiung; Liu, Ying-Ling

    2015-08-18

    This work demonstrates a new class of thermosetting resins, based on Meldrum's acid (MA) derivatives, which have high fractions of free volume and inherently low k values of about 2.0 at 1 MHz. Thermal decomposition of the MA groups evolves CO2 and acetone to create air-trapped cavities so as to reduce the dielectric constants.

  9. An corrective method to correct of the inherent flaw of the asynchronization direct counting circuit

    International Nuclear Information System (INIS)

    Wang Renfei; Liu Congzhan; Jin Yongjie; Zhang Zhi; Li Yanguo

    2003-01-01

    As a inherent flaw of the Asynchronization Direct Counting Circuit, the crosstalk, which is resulted from the randomicity of the time-signal always exists between two adjacent channels. In order to reduce the counting error derived from the crosstalk, the author propose an effective method to correct the flaw after analysing the mechanism of the crosstalk

  10. Location estimation of approaching objects is modulated by the observer's inherent and momentary action capabilities

    NARCIS (Netherlands)

    Kandula, Manasa; Hofman, Dennis; Dijkerman, H Chris

    2016-01-01

    Action capability may be one of the factors that can influence our percept of the world. A distinction can be made between momentary action capability (action capability at that particular moment) and inherent action capability (representing a stable action capability). In the current study, we

  11. 16 CFR 1211.13 - Inherent force activated secondary door sensors.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Inherent force activated secondary door sensors. 1211.13 Section 1211.13 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT... across the door so that the axis is perpendicular to the plane of the door. See Figure 6 of this part...

  12. 40 CFR 88.312-93 - Inherently Low-Emission Vehicle labeling.

    Science.gov (United States)

    2010-07-01

    ... stroke width not less than 0.5 inches (1.3 centimeters). In addition, the words “INHERENTLY LOW-EMISSION..., the words “CLEAN AIR VEHICLE” must be present in lettering no smaller than 0.8 inches (2.0 centimeters... loan to someone who has not demonstrated eligibility for expanded TCMs available to ILEVs according to...

  13. [The concentration of growth factors in patients with inherent and acquired shortenings of limbs bones].

    Science.gov (United States)

    Strogov, M V; Luneva, S N; Novikov, K I

    2013-04-01

    The article deals with the results of study of level of growth factors in blood serum of patients with inherent and post-traumatic shortenings of limbs' bones. The detection in blood serum the level of epidermal growth factor insulin-like growth factor I and angiopoetins is proposed to monitor in given patients the reparative bone formation.

  14. Toxic release consequence analysis tool (TORCAT) for inherently safer design plant

    International Nuclear Information System (INIS)

    Shariff, Azmi Mohd; Zaini, Dzulkarnain

    2010-01-01

    Many major accidents due to toxic release in the past have caused many fatalities such as the tragedy of MIC release in Bhopal, India (1984). One of the approaches is to use inherently safer design technique that utilizes inherent safety principle to eliminate or minimize accidents rather than to control the hazard. This technique is best implemented in preliminary design stage where the consequence of toxic release can be evaluated and necessary design improvements can be implemented to eliminate or minimize the accidents to as low as reasonably practicable (ALARP) without resorting to costly protective system. However, currently there is no commercial tool available that has such capability. This paper reports on the preliminary findings on the development of a prototype tool for consequence analysis and design improvement via inherent safety principle by utilizing an integrated process design simulator with toxic release consequence analysis model. The consequence analysis based on the worst-case scenarios during process flowsheeting stage were conducted as case studies. The preliminary finding shows that toxic release consequences analysis tool (TORCAT) has capability to eliminate or minimize the potential toxic release accidents by adopting the inherent safety principle early in preliminary design stage.

  15. The Inherent Politics of Managing the Quality of Urban Green Spaces

    DEFF Research Database (Denmark)

    Lindholst, Christian; Sullivan, Sidney George; Konijnendijk van den Bosch, Cecil C.

    2015-01-01

    of such ‘inherent politics’ through a case study of a widespread approach to operationalizing quality in urban green space management. We conclude that adoption of any quality model has both limiting and enabling implications for public participation and decision-making and that a critical stance is needed within...

  16. Manson Chicks and Microskirted Cuties : Pornification in Thomas Pynchon's Inherent Vice

    NARCIS (Netherlands)

    Cook, S.J.|info:eu-repo/dai/nl/411939432

    2015-01-01

    Many sexual encounters in Thomas Pynchon’s fiction have occurred beyond the mainstream, generating theatres of perversity which dramatise the death wish and enact power relations from wider arenas. However, in Inherent Vice they change in nature. With the exception of scenes which use Charles Manson

  17. Development status of PIUS/ISER - a inherently safe reactor for the international use

    International Nuclear Information System (INIS)

    Wakabayashi, Hiroaki

    1987-01-01

    It is just in early 1980s that LWR-based nuclear power has become a substantial power source. Though the safety level of nuclear power is always claimed to be sufficiently high by the industry, it rests on the idea of defense in depth, the calculation by probabilistic risk assessment (PRA) or probabilistic safety assessment (PSA). The TMI-2 and Chernobyl-4 accidents occurred in the industrially most advanced countries. In this paper, an alternative way to safe nuclear power is sought in so-called inherently safe reactors (ISR) including the LWR type PIUS/ISER. With proper consideration into the design of nuclear reactor plants, those can be made basically safe through the use of passive safe mechanism for their design. In short, an ISR is a nuclear power reactor which has passive and intrinsic core cooling capability and automatic shutdown capability. As the nuclear power reactors which are currently claimed to be inherently safe, there are the process inherent and ultimately safe reactor (PIUS) of ASEA-ATOM Sweden and the inherently safe and economical reactor (ISER) of the University of Tokyo, Japan, of LWR type. The current status of the development, the reliability, and some technical problems of ISER/PIUS and the attitude of various countries toward ISER/PIUS are described. (Kako, I.)

  18. Food plant toxicants and safety: risk assessment and regulation of inherent toxicants in plant foods.

    NARCIS (Netherlands)

    Essers, A.J.; Alink, G.M.; Speijers, G.J.A.; Alexander, J.; Bouwmeister, P.J.; Brandt, van den P.A.; Ciere, S.; Gry, J.; Herrman, J.; Kuiper, H.A.; Mortby, E.; Renwickn, A.G.

    1998-01-01

    The ADI as a tool for risk management and regulation of food additives and pesticide residues is not readily applicable to inherent food plant toxicants: The margin between actual intake and potentially toxic levels is often small; application of the default uncertainty factors used to derive ADI

  19. Unlocking variability: inherent variation and developmental traits of garlic plants originated from sexual reproduction

    NARCIS (Netherlands)

    Shemesh, E.; Scholten, O.E.; Rabinowitch, H.D.; Kamenetsky, R.

    2008-01-01

    Recent collections of fertile garlic (Allium sativum) accessions from Central Asia allow a detailed study of seedling developments and the evaluation of inherent variations. We hereby provide a comprehensive account of the ontogenesis of a population of garlic seedlings and their vegetative and

  20. The attractive Achilles heel of germ cell tumours : an inherent sensitivity to apoptosis-inducing stimuli

    NARCIS (Netherlands)

    Spierings, DCJ; de Vries, EGE; Vellenga, E; de Jong, S

    Testicular germ cell tumours (TGCTs) are extremely sensitive to cisplatin-containing chemotherapy. The rapid time course of apoptosis induction after exposure to cisplatin suggests that TGCT cells are primed to undergo programmed cell death as an inherent property of the cell of origin. In fact,

  1. Efficiency of inherent protection mechanisms for an improved HTR safety concept

    Energy Technology Data Exchange (ETDEWEB)

    Petersen, K.; Buescher, R.; Gerwin, H.; Schenk, W. [Kernforschungsanlage Juelich G.m.b.H. (Germany, F.R.). Inst. fuer Reaktorentwicklung

    1981-01-15

    For a preliminary design of a 350 MWsub(th) annular core derived from AVR-reactor the efficiency of inherent protection mechanisms is discussed. After-heat removal and auto-shut down potential are demonstrated for intact and complete failure of core heat sinks.

  2. Making the Grade: Describing Inherent Requirements for the Initial Teacher Education Practicum

    Science.gov (United States)

    Sharplin, Elaine; Peden, Sanna; Marais, Ida

    2016-01-01

    This study explores the development, description, and illustration of inherent requirement (IR) statements to make explicit the requirements for performance on an initial teacher education (ITE) practicum. Through consultative group processes with stakeholders involved in ITE, seven IR domains were identified. From interviews with academics,…

  3. Developing Students' Reflections on the Function and Status of Mathematical Modeling in Different Scientific Practices: History as a Provider of Cases

    Science.gov (United States)

    Kjeldsen, Tinne Hoff; Blomhøj, Morten

    2013-01-01

    Mathematical models and mathematical modeling play different roles in the different areas and problems in which they are used. The function and status of mathematical modeling and models in the different areas depend on the scientific practice as well as the underlying philosophical and theoretical position held by the modeler(s) and the…

  4. Inherent Safety Feature of Hybrid Low Power Research Reactor during Reactivity Induced Accident

    Energy Technology Data Exchange (ETDEWEB)

    Kim, DongHyun; Yum, Soo Been; Hong, Sung Teak; Lim, In-Cheol [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    Hybrid low power research reactor(H-LPRR) is the new design concept of low power research reactor for critical facility as well as education and training. In the case of typical low power research reactor, the purposes of utilization are the experiments for education of nuclear engineering students, Neutron Activation Analysis(NAA) and radio-isotope production for research purpose. H-LPRR is a light-water cooled and moderated research reactor that uses rod-type LEU UO{sub 2} fuels same as those for commercial power plants. The maximum core thermal power is 70kW and, the core is placed in the bottom of open pool. There are 1 control rod and 2 shutdown rods in the core. It is designed to cool the core by natural convection, retain negative feedback coefficient for entire fuel periods and operate for 20 years without refueling. Inherent safety in H-LPRR is achieved by passive design features such as negative temperature feedback coefficient and core cooling by natural convection during normal and emergency conditions. The purpose of this study is to find out that the inherent safety characteristics of H-LPRR is able to control the power and protect the reactor from the RIA(Reactivity induced accident). RIA analysis was performed to investigate the inherent safety feature of H-LPRR. As a result, it was found that the reactor controls its power without fuel damage in the event and that the reactor remains safe states inherently. Therefore, it is believed that high degree of safety inheres in H-LPRR.

  5. Abnormalities in Left Ventricular Rotation Are Inherent in Young Children with Repaired Tetralogy of Fallot and Are Independent of Right Ventricular Dilation.

    Science.gov (United States)

    Karnik, Ruchika; Uppu, Santosh C; Tozzi, Meghan; Doucette, John; Lytrivi, Irene D; Geiger, Miwa; Klas, Berthold; Parness, Ira A; Shenoy, Rajesh; Rajagopal, Hari; Srivastava, Shubhika

    2018-04-11

    Left ventricular (LV) dysfunction is a risk factor for adverse outcomes in older children and adults with repaired Tetralogy of Fallot (rToF). Pulmonary regurgitation (PR), right ventricular (RV) dilation, and dysfunction have been shown to result in abnormal LV myocardial mechanics and dysfunction. The aim of our study was to evaluate LV rotational mechanics, especially apical rotation in young children with rToF with and without RV dilation. This is a retrospective, single center study in 28 asymptomatic young children with rToF (16 with RV dilation; 12 without RV dilation); 29 age-matched normal controls. RV and LV systolic and diastolic function was studied using conventional two-dimensional echocardiography (2DE) and speckle tracking echocardiography (STE). Rotational mechanics studied included basal and apical rotation (BR, AR), peak twist (calculated by difference between the apical and basal rotation), twist rate (TR), and untwist rate (UnTR). The mean age of the cohort was 4.7 years (± 2.3). Abnormal AR, BR, TR, and UnTR were noted in patients with rToF. The abnormalities were significant in magnitude as well as the direction of rotation; more pronounced in the absence of RV dilation. LV systolic and diastolic dysfunction as evidenced by abnormal AR and degree of untwist is inherent in rToF and not associated with RV dilation in rToF children. Abnormal BR may reflect a lack of maturation to adult type of rotational mechanics. Further longitudinal studies are required to study the progression of these abnormalities and their correlation with clinical outcomes.

  6. Listening to Other Voices: A Description of Teacher Reflection in the United States.

    Science.gov (United States)

    Valli, Linda

    1997-01-01

    Examines reflective teaching, discussing the meaning of reflection; the origins of reflection; the popularity and importance of reflective teaching; different types of reflective teaching (technical reflection, deliberative reflection, personalistic reflection, critical reflection, and reflection-in and on-action); and how teacher educators can…

  7. Two different preparation techniques for trace element determination of single Daphnia specimen using total reflection x-ray fluorescence analysis (TXRF)

    International Nuclear Information System (INIS)

    Woelfl, S.; Mages, M.

    2000-01-01

    Bio accumulation gives first information about the bio-availability of elements in waters and becomes more and more important for the characterization of the water quality. The use of common analytical techniques like ICP-MS and AAS requires large quantities of biologic sample material. Single preparation for example of Daphnia, a common species for bio-test experiments, are hardly possible with these procedures. Therefore alternatively quantitative TXRF element determination of individually prepared Daphnia was developed. Two preparation techniques for single freshwater crustacean specimen from a eutrophic branch of the river Elbe in the 'Rothehorn Park', Magdeburg (Daphnia: dry weight: 10 - 50 μg individuum -1 ) had been tested: (1) Wet preparation: the single Daphnia specimen had been washed with 0.45 μm filtered lake water and put onto quartz sample carriers. After air drying, the body length were determined in order to calculate the dry weight according to previously established body lengths-dry weight relationships. (2) Dry preparation: after collection specimen were washed with 0.45 μm filtered lake water and frozen in liquid nitrogen. The individual lyophilisated dried Daphnia were weighted using an ultrafine micro-balance and put onto quartz sample carriers. After preparation, addition of some μl Gallium standard solution and air drying the individual Daphnia were digested at the quartz sample carriers with 10 μl HNO 3 on a hot plate and dried once more. Finally the element concentrations were determined using a EXTRA IIA total-reflection x-ray fluorescence spectrometer. As a result of these investigations we can conclude that both, the 'dry' and 'wet' preparation method can be used for the element determination in small single crustaceans using TXRF spectrometry. It seems that the 'dry' method yields more precise results, but the wet method is easier to handle in field when samples cannot be fixed with liquid nitrogen. (author)

  8. Bacterial diversity shift determined by different diets in the gut of the spotted wing fly Drosophila suzukii is primarily reflected on acetic acid bacteria

    KAUST Repository

    Vacchini, Violetta; Gonella, Elena; Crotti, Elena; Prosdocimi, Erica M.; Mazzetto, Fabio; Chouaia, Bessem; Callegari, Matteo; Mapelli, Francesca; Mandrioli, Mauro; Alma, Alberto; Daffonchio, Daniele

    2016-01-01

    The pivotal role of diet in shaping gut microbiota has been evaluated in different animal models, including insects. Drosophila flies harbour an inconstant microbiota among which acetic acid bacteria (AAB) are important components. Here, we

  9. Challenging Narcissus, or Reflecting on Reflecting.

    Science.gov (United States)

    Achilles, C. M.

    The concept of reflective practice and teaching people to be reflective practitioners is examined. The document begins with a look at professional knowledge according to three prominent professionals in the educational administration field: Schon, Schein, and Achilles. "Reflective" strategies that could be incorporated into courses and…

  10. Inherent optical properties of Zamzam water in the visible spectrum: Dispersion analysis

    International Nuclear Information System (INIS)

    El-Zaiat, S.Y.

    2007-01-01

    Water samples have been taken from Zamzam well that is located in the holy city of Makkah in the Kingdom of Saudi Arabia. Refractive indices of Zamzam water samples have been measured by an Abbe refractometer at six discrete wavelengths across the visible spectrum. Some related optical parameters such as: group refractive index; permittivity; specific refraction; polarizability; reflectance and transmittance have been deduced. Dispersion of these optical parameters across the visible spectrum has been calculated. For comparison, these optical parameters have been determined for two samples of bottled drinking and distilled waters. Also the Abbe number and the single oscillator constants for the three waters have been calculated. Error analyses of the measured and calculated optical parameters have been given. It has been concluded that Zamzam water has special optical parameters that are different than those of bottled bottled drinking and distilled waters. (author)

  11. Integral Inherently Safe Light Water Reactor (I2S-LWR)

    International Nuclear Information System (INIS)

    Petrovic, Bojan; Memmott, Matthew; Boy, Guy; Charit, Indrajit; Manera, Annalisa; Downar, Thomas; Lee, John; Muldrow, Lycurgus; Upadhyaya, Belle; Hines, Wesley; Haghighat, Alierza

    2017-01-01

    This final report summarizes results of the multi-year effort performed during the period 2/2013- 12/2016 under the DOE NEUP IRP Project ''Integral Inherently Safe Light Water Reactors (I 2 S-LWR)''. The goal of the project was to develop a concept of a 1 GWe PWR with integral configuration and inherent safety features, at the same time accounting for lessons learned from the Fukushima accident, and keeping in mind the economic viability of the new concept. Essentially (see Figure 1-1) the project aimed to implement attractive safety features, typically found only in SMRs, to a larger power (1 GWe) reactor, to address the preference of some utilities in the US power market for unit power level on the order of 1 GWe.

  12. Passive and inherent safety technologies for light-water nuclear reactors

    International Nuclear Information System (INIS)

    Forsberg, C.W.

    1990-07-01

    Passive/inherent safety implies a technical revolution in our approach to nuclear power safety. This direction is discussed herein for light-water reactors (LWRs) -- the predominant type of power reactor used in the world today. At Oak Ridge National Laboratory (ORNL) the approach to the development of passive/inherent safety for LWRs consists of four steps: identify and quantify safety requirements and goals; identify and quantify the technical functional requirements needed for safety; identify, invent, develop, and quantify technical options that meet both of the above requirements; and integrate safety systems into designs of economic and reliable nuclear power plants. Significant progress has been achieved in the first three steps of this program. The last step involves primarily the reactor vendors. These activities, as well as related activities worldwide, are described here. 27 refs., 7 tabs

  13. Integral Inherently Safe Light Water Reactor (I2S-LWR)

    Energy Technology Data Exchange (ETDEWEB)

    Petrovic, Bojan [Georgia Inst. of Technology, Atlanta, GA (United States); Memmott, Matthew [Brigham Young Univ., Provo, UT (United States); Boy, Guy [Florida Inst. of Technology, Melbourne, FL (United States); Charit, Indrajit [Univ. of Idaho, Moscow, ID (United States); Manera, Annalisa [Univ. of Michigan, Ann Arbor, MI (United States); Downar, Thomas [Univ. of Michigan, Ann Arbor, MI (United States); Lee, John [Univ. of Michigan, Ann Arbor, MI (United States); Muldrow, Lycurgus [Morehouse College, Atlanta, GA (United States); Upadhyaya, Belle [Univ. of Tennessee, Knoxville, TN (United States); Hines, Wesley [Univ. of Tennessee, Knoxville, TN (United States); Haghighat, Alierza [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States)

    2017-10-02

    This final report summarizes results of the multi-year effort performed during the period 2/2013- 12/2016 under the DOE NEUP IRP Project “Integral Inherently Safe Light Water Reactors (I2S-LWR)”. The goal of the project was to develop a concept of a 1 GWe PWR with integral configuration and inherent safety features, at the same time accounting for lessons learned from the Fukushima accident, and keeping in mind the economic viability of the new concept. Essentially (see Figure 1-1) the project aimed to implement attractive safety features, typically found only in SMRs, to a larger power (1 GWe) reactor, to address the preference of some utilities in the US power market for unit power level on the order of 1 GWe.

  14. Is damage to the common bile duct during laparoscopic cholecystectomy an inherent risk of the operation?

    Science.gov (United States)

    Fischer, Josef E

    2009-06-01

    Laparoscopic cholocystectomy has been practiced for close to 20 years. The rate of common duct injury remains somewhere between 0.4 to 0.7 percent and is approximately the same around the world. Recent papers have stressed ways in which laparoscopic common duct injury can be avoided, but none of the methods mentioned is foolproof. In addition, this complication can occur to even the most experienced laparoscopic surgeon. The author believes that injury to the common duct during laparoscopic cholocystectomy is not a result of the practice below the standard, but an inherent risk of the operation. This injury needs to be emphasized by the surgical community as an inherent risk of the operation, and patients should be fully informed of this potential complication.

  15. Role of FFTF in assessing structural feedbacks and inherent safety of LMR's

    International Nuclear Information System (INIS)

    Padilla, A.; Omberg, R.P.; O'Dell, L.D.; Harris, R.A.; Nguyen, D.H.; Waltar, A.E.

    1985-03-01

    The possibility of developing reactor designs with inherent safety characteristics sufficient to provide ''walk away'' safety is receiving additional emphasis in the LMR program. A key element in this effort is the recognition that LMR's possess safety characteristics above and beyond those employed in past safety review processes. Some of these additional safety characteristics are due to reactivity feedback effects caused by small structural movements during hypothetical severe design transients. The effect of these characteristics upon the behavior of the FFTF under such transients has been assessed and is discussed in this paper. The paper also presents a preliminary test matrix which might allow experimental verification of the structural reactivity feedback effects. Such experimental verification should be very useful to innovative designers seeking to optimize inherent safety. 8 refs., 1 fig., 2 tabs

  16. A simplified analysis of uncertainty propagation in inherently controlled ATWS events

    International Nuclear Information System (INIS)

    Wade, D.C.

    1987-01-01

    The quasi static approach can be used to provide useful insight concerning the propagation of uncertainties in the inherent response to ATWS events. At issue is how uncertainties in the reactivity coefficients and in the thermal-hydraulics and materials properties propagate to yield uncertainties in the asymptotic temperatures attained upon inherent shutdown. The basic notion to be quantified is that many of the same physical phenomena contribute to both the reactivity increase of power reduction and the reactivity decrease of core temperature rise. Since these reactivities cancel by definition, a good deal of uncertainty cancellation must also occur of necessity. For example, if the Doppler coefficient is overpredicted, too large a positive reactivity insertion is predicted upon power reduction and collapse of the ΔT across the fuel pin. However, too large a negative reactivity is also predicted upon the compensating increase in the isothermal core average temperature - which includes the fuel Doppler effect

  17. An assessment of the low seismic risk of the inherently safe sodium advanced fast reactor (SAFR)

    International Nuclear Information System (INIS)

    Rutherford, P.D.

    1988-01-01

    A recent probabilistic risk assessment (PRA) of the sodium advanced fast reactor (SAFR) demonstrated the inherently low risk of advanced liquid-metal, pool-type fast reactors with inherent safety systems. As a result, it was recognized that external events, especially seismic events, may not only be a major contributor to risk (as shown in several LWR PRAs) but also may completely dominate the risk. Accordingly, a seismic risk assessment has been completed for SAFR, which resulted in a core damage frequency of 2 x 10 -7 /year and a large release frequency of 4 x 10 -9 /year. This paper reports that public health risk in terms of early fatality risk and latent fatality risk were also several orders of magnitude below the NRC safety goals and below recent LWR risks reported in NUREB/CR1150

  18. Acoustic resonance scattering by a system of concentrically multilayered shells: the inherent background and resonance coefficients

    CERN Document Server

    Choi, M S; Lee, S H

    1999-01-01

    The inherent background coefficients that exactly describe the background amplitudes in the scattered field have been presented for the scattering of plane acoustic waves by a system of concentrically multilayered solid and/or fluid shells submerged in a fluid. The coefficients have been obtained by replacing the mechanical surface admittance function with the zero-frequency limit of the admittance function for the analogous fluid system, where the shear wave speeds in the solid layers are set to zero. By taking advantage of the concept of incoming and outgoing waves, we find the surface admittance function for the fluid system in such a form that the analytical generalization for any number of layers and the physical interpretation are very easy. The background coefficients obtained are independent of the bulk wave speeds in the system: they depend on the mass densities and the thickness of the shells. With increasing frequency, the inherent background undergoes a transition from the soft to the rigid backgr...

  19. Imaging Hybrid Photon Detectors with a Reflective Photocathode

    CERN Document Server

    Ferenc, D

    2000-01-01

    Modern epitaxially grown photocathodes, like GaAsP, bring a very high inherent quantum efficiency, but are rather expensive due to the complicated manufacturing and mounting process. We argue that such photocathodes could be used in reflective mode, in order to avoid the risky and expensive removal of the epitaxial growth substrate. Besides that the quantum efficiency should increase considerably. In this paper we present results of the development of large imaging Hybrid Photon Detectors (HPDs), particularly designed for such reflective photocathodes.

  20. Disease resistance is related to inherent swimming performance in Atlantic salmon

    OpenAIRE

    Castro, Vicente; Grisdale-Helland, Barbara; Jørgensen, Sven Martin; Helgerud, Jan; Claireaux, Guy; Farrell, Anthony P.; Krasnov, Aleksei; Helland, Ståle; Takle, Harald Rune

    2013-01-01

    Background Like humans, fish can be classified according to their athletic performance. Sustained exercise training of fish can improve growth and physical capacity, and recent results have documented improved disease resistance in exercised Atlantic salmon. In this study we investigated the effects of inherent swimming performance and exercise training on disease resistance in Atlantic salmon. Atlantic salmon were first classified as either poor or good according to their swimming per...

  1. Ethical problems inherent in psychological research based on internet communication as stored information

    DEFF Research Database (Denmark)

    Øhrstrøm, Peter; Dyhrberg, Johan

    2007-01-01

    This paper deals with certain ethical problems inherent in psychological research based on internet communication as stored information. Section 1 contains an analysis of research on Internet debates. In particular, it takes into account a famous example of deception for psychology research...... purposes. In section 2, the focus is on research on personal data in texts published on the Internet. Section 3 includes an attempt to formulate some ethical principles and guidelines, which should be regarded as fundamental in research on stored information....

  2. Interaction between bovine-associated coagulase-negative staphylococci species and strains and bovine mammary epithelial cells reflects differences in ecology and epidemiological behavior.

    Science.gov (United States)

    Souza, F N; Piepers, S; Della Libera, A M M P; Heinemann, M B; Cerqueira, M M O P; De Vliegher, S

    2016-04-01

    Bacteria adherence seems to be an essential first stage for the internalization of bacteria into the cytoplasm of the host cell, which is considered an important virulence strategy enabling bacteria to occupy a microenvironment separated from host defense mechanisms. Thus, this study aimed to explore the difference in the capacity of 4 bovine-associated staphylococci species or strains to adhere to and internalize into bovine mammary epithelial cells (MEC). Three different isolates of coagulase-negative staphylococci (CNS) were used: one strain of Staphylococcus fleurettii isolated from sawdust and considered an environmental opportunistic bacterium, and 2 dissimilar Staphylococcus chromogenes isolates, one cultured from a heifer's teat apex (Staph. chromogenes TA) and the other originating from a chronic intramammary infection (Staph. chromogenes IM). Also, one well-characterized strain of Staphylococcus aureus (Newbould 305) was used for comparison with a major mastitis pathogen. The CNS species and strains adhered to and internalized into MEC slower than did Staph. aureus. Still, we observed high variation in adhesion and internalization capacity among the different CNS, with Staph. chromogenes IM showing a greater ability to adhere to and internalize into MEC than the 2 CNS strains isolated from extramammary habitats. In conclusion, the 3 well-characterized bovine-associated CNS species and strains originating from distinct habitats showed clear differences in their capacity to adhere to and internalize into MEC. The observed differences might be related to their diversity in ecology and epidemiological behavior. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  3. An overview of approaches and challenges for retrieving marine inherent optical properties from ocean color remote sensing

    Science.gov (United States)

    Werdell, P. Jeremy; McKinna, Lachlan I. W.; Boss, Emmanuel; Ackleson, Steven G.; Craig, Susanne E.; Gregg, Watson W.; Lee, Zhongping; Maritorena, Stéphane; Roesler, Collin S.; Rousseaux, Cécile S.; Stramski, Dariusz; Sullivan, James M.; Twardowski, Michael S.; Tzortziou, Maria; Zhang, Xiaodong

    2018-01-01

    Ocean color measured from satellites provides daily global, synoptic views of spectral water-leaving reflectances that can be used to generate estimates of marine inherent optical properties (IOPs). These reflectances, namely the ratio of spectral upwelled radiances to spectral downwelled irradiances, describe the light exiting a water mass that defines its color. IOPs are the spectral absorption and scattering characteristics of ocean water and its dissolved and particulate constituents. Because of their dependence on the concentration and composition of marine constituents, IOPs can be used to describe the contents of the upper ocean mixed layer. This information is critical to further our scientific understanding of biogeochemical oceanic processes, such as organic carbon production and export, phytoplankton dynamics, and responses to climatic disturbances. Given their importance, the international ocean color community has invested significant effort in improving the quality of satellite-derived IOP products, both regionally and globally. Recognizing the current influx of data products into the community and the need to improve current algorithms in anticipation of new satellite instruments (e.g., the global, hyperspectral spectroradiometer of the NASA Plankton, Aerosol, Cloud, ocean Ecosystem (PACE) mission), we present a synopsis of the current state of the art in the retrieval of these core optical properties. Contemporary approaches for obtaining IOPs from satellite ocean color are reviewed and, for clarity, separated based their inversion methodology or the type of IOPs sought. Summaries of known uncertainties associated with each approach are provided, as well as common performance metrics used to evaluate them. We discuss current knowledge gaps and make recommendations for future investment for upcoming missions whose instrument characteristics diverge sufficiently from heritage and existing sensors to warrant reassessing current approaches.

  4. Model development for the dynamic analysis of the OSU inherently safe reactor. Part 1

    International Nuclear Information System (INIS)

    Aybar, H.S.

    1992-01-01

    Faculty and students in the Nuclear Engineering Program at the Ohio State University (OSU) have proposed a conceptual design for an inherently safe 340 MWe power reactor. The design is based on the state-of-the-art technology of LWRs and the High Temperature Gas- cooled Reactors (HTGRs). The OSU Inherently Safe Reactor (OSU-ISR) concept uses shorter than standard BWR fuel elements in the reactor core. All the fluid on the primary side is contained within a Prestressed Concrete Reactor Vessel (PCRV). This important feature significantly reduces the probability of a LOCA. A new feature of the OSU-ISR is an operator independent steam driven Emergency Core Cooling System (ECCS) housed within the PCRV. In accident conditions where the steam generators are incapacitated, steam from the core drives a jet injector, which takes water from the suppression pool and pumps it into the core cavity to maintain core coverability. The preliminary analysis of the concept was performed as a design project in the Nuclear Engineering Program at the OSU during the Spring of 1985, and published in ''Nuclear Technology.'' The use of a PCRV for ducting and containment and the replacement of forced recirculation with natural circulation on the primary side significantly improve the inherent safety of the plant. Currently, work is in progress for the refinement of the OSU-ISR concept, partially supported by a grant from the U.S. Department of Energy

  5. Interdependency control : compensation strategies for the inherent vulnerability of critical infrastructure networks

    International Nuclear Information System (INIS)

    Mao, D.; Sotoodeh, M.; Monu, K.; Marti, J.R.; Srivastava, K.D.

    2009-01-01

    Today's increasingly interacting national critical infrastructures (NCIs) can tolerate most stochastic local disturbances. However, they are extremely fragile under global disturbances, as the latter may either push the whole system into a critical state or reveal many unexpected hidden interdependencies, inducing or triggering cascading failures among all possible layers. This robust yet fragile duality is an inherent vulnerability of modern infrastructures. It is therefore expected that weather-related disasters will be more frequent under a changing climate. This paper proposed an interdependency control strategy (ICS) that would maintain the survival of the most critical services, and compensate for this inherent vulnerability during emergency states. The paper also proposed a generalized adjacency matrix (GAM) to represent the physical interdependencies intra/inter of various infrastructure networks. The vulnerable section in the network can be identified, based on computed results of GAM, number of islands in the network, and influence domain(s) of each component. These features render ICS more effective and convincing. Last, the paper proposed a survivability index for isolated sub-networks and described relevant measures for improving this index during the four phases of emergency management. It was concluded that the proposed strategy is an effective means to reduce the inherent vulnerability and increase the resiliency of these critical infrastructures networks. 20 refs., 5 figs

  6. Possibility of a pressurized water reactor concept with highly inherent heat removal following capability

    International Nuclear Information System (INIS)

    Araya, Fumimasa; Murao, Yoshio

    1995-01-01

    If the core power inherently follows change in heat removal rate from the primary coolant system within small thermal expansion of the coolant which can be absorbed in a practical size of pressurizer, reactor systems may have more safety and load following capability. In order to know possibility and necessary conditions of a concept on reactor core and primary coolant system of a pressurized water reactor (PWR) with such 'highly inherent heat removal following capability', transient analyses on an ordinary two-loop PWR have been performed for a transient due to 50% change in heat removal with the RETRAN-02 code. The possibility of a PWR concept with the highly inherent heat removal following capability has been demonstrated under the conditions of the absolute value of ratio of the coolant density reactivity coefficient to the Doppler reactivity coefficient more than 10x10 3 kg·cm 3 which is two to three times larger than that at beginning of cycle (BOC) in an ordinary PWR and realized by elimination of the chemical shim, the 12% lower average linear heat generation rate of 17.9 kW/m, and the 1.5 times larger pressurizer volume than those of the ordinary PWR. (author)

  7. A compact, inherently safe liquid metal reactor plant concept for terrestrial defense power applications

    International Nuclear Information System (INIS)

    Magee, P.M.; Dubberley, A.E.; Lutz, D.E.; Palmer, R.S.

    1987-01-01

    A compact, inherently safe, liquid metal reactor concept based on the GE PRISM innovative LMR design has been developed for terrestrial defense power applications in the 2-50 MWe range. The concept uses a small, sodium-cooled, U-5%Zr metal fueled reactor contained within two redundant steel vessels. The core is designed to operate at a low power density and temperature (925 F) and can operate 30 years without refueling. One two primary coolant loops, depending upon the plant size, transport heat from the core to sodium-to-air, double-wall heat exchangers. Power is produced by a gas turbine operated in a closed ''bottoming'' cycle that employs intercoolers between the compressor stages and a recuperator. Inherent safety is provided by passive means only; operator action is not required to ensure plant safety even for events normally considered Beyond Design Basis Accidents. In addition to normal shutdown heat removal via the sodium-to-air heat exchangers, the design utilizes an inherently passive radiant vessel auxiliary cooling system similar to that designed for PRISM. The use of an air cycle gas turbine eliminates the cost and complexity of the sodium-water reactor pressure relief system required for a steam cycle sodium-cooled reactor

  8. Developing a model for hospital inherent safety assessment: Conceptualization and validation.

    Science.gov (United States)

    Yari, Saeed; Akbari, Hesam; Gholami Fesharaki, Mohammad; Khosravizadeh, Omid; Ghasemi, Mohammad; Barsam, Yalda; Akbari, Hamed

    2018-01-01

    Paying attention to the safety of hospitals, as the most crucial institute for providing medical and health services wherein a bundle of facilities, equipment, and human resource exist, is of significant importance. The present research aims at developing a model for assessing hospitals' safety based on principles of inherent safety design. Face validity (30 experts), content validity (20 experts), construct validity (268 examples), convergent validity, and divergent validity have been employed to validate the prepared questionnaire; and the items analysis, the Cronbach's alpha test, ICC test (to measure reliability of the test), composite reliability coefficient have been used to measure primary reliability. The relationship between variables and factors has been confirmed at 0.05 significance level by conducting confirmatory factor analysis (CFA) and structural equations modeling (SEM) technique with the use of Smart-PLS. R-square and load factors values, which were higher than 0.67 and 0.300 respectively, indicated the strong fit. Moderation (0.970), simplification (0.959), substitution (0.943), and minimization (0.5008) have had the most weights in determining the inherent safety of hospital respectively. Moderation, simplification, and substitution, among the other dimensions, have more weight on the inherent safety, while minimization has the less weight, which could be due do its definition as to minimize the risk.

  9. Does the think-aloud protocol reflect thinking? Exploring functional neuroimaging differences with thinking (answering multiple choice questions) versus thinking aloud

    NARCIS (Netherlands)

    Durning, S.J.; Artino, A.R.; Beckman, T.J.; Graner, J.; Vleuten, C.P.M. van der; Holmboe, E.; Schuwirth, L.

    2013-01-01

    Background: Whether the think-aloud protocol is a valid measure of thinking remains uncertain. Therefore, we used functional magnetic resonance imaging (fMRI) to investigate potential functional neuroanatomic differences between thinking (answering multiple-choice questions in real time) versus

  10. Modelling and Order of Acoustic Transfer Functions Due to Reflections from Augmented Objects

    Directory of Open Access Journals (Sweden)

    Diemer de Vries

    2007-01-01

    Full Text Available It is commonly accepted that the sound reflections from real physical objects are much more complicated than what usually is and can be modelled by room acoustics modelling software. The main reason for this limitation is the level of detail inherent in the physical object in terms of its geometrical and acoustic properties. In the present paper, the complexity of the sound reflections from a corridor wall is investigated by modelling the corresponding acoustic transfer functions at several receiver positions in front of the wall. The complexity for different wall configurations has been examined and the changes have been achieved by altering its acoustic image. The results show that for a homogenous flat wall, the complexity is significant and for a wall including various smaller objects, the complexity is highly dependent on the position of the receiver with respect to the objects.

  11. Movie Popularity Classification based on Inherent Movie Attributes using C4.5, PART and Correlation Coefficient

    DEFF Research Database (Denmark)

    Ibnal Asad, Khalid; Ahmed, Tanvir; Rahman, Md. Saiedur

    2012-01-01

    Abundance of movie data across the internet makes it an obvious candidate for machine learning and knowledge discovery. But most researches are directed towards bi-polar classification of movie or generation of a movie recommendation system based on reviews given by viewers on various internet...... sites. Classification of movie popularity based solely on attributes of a movie i.e. actor, actress, director rating, language, country and budget etc. has been less highlighted due to large number of attributes that are associated with each movie and their differences in dimensions. In this paper, we...... propose classification scheme of pre-release movie popularity based on inherent attributes using C4.S and PART classifier algorithm and define the relation between attributes of post release movies using correlation coefficient....

  12. Ulcerative colitis, Crohn's disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn's disease

    DEFF Research Database (Denmark)

    Mortensen, Joachim Høg; Manon-Jensen, Tina; Jensen, Michael Dam

    2017-01-01

    patients, 22 patients with irritable bowel syndrome (IBS), and 24 healthy donors. One-way analysis of variance, Mann-Whitney U-test, logistic regression models, and receiver operator characteristics (ROC) curve analysis was carried out to evaluate the diagnostic accuracy of the biomarkers. The ECM...... remodelling was significantly different in UC compared to CD. The best biomarker combination to differentiate UC from CD and colonic CD was BGM and VICM (AUC = 0.98, P5mg/mL), correlation of Pro-C5 (r = 0.36) with CDAI was slightly improved compared to CRP (r = 0.27) corrected for the use of immunosuppressant....... Furthermore, BGM and EL-NE biomarkers were highly associated with colon inflammation in CD patients. ECM fragments of tissue remodelling in IBD affect UC and CD differently, and may aid in differentiating IBD from IBS (EL-NE, BGM, Pro-C5), and UC from CD patients (BGM, VICM). Formation of type V collagen...

  13. Different combinations of maternal and postnatal diet are reflected in changes of hepatic parenchyma and hepatic TNF-alpha expression in male rat offspring.

    Science.gov (United States)

    Kačarević, Željka Perić; Grgić, Anđela; Šnajder, Darija; Bijelić, Nikola; Belovari, Tatjana; Cvijanović, Olga; Blažičević, Valerija; Radić, Radivoje

    2017-09-01

    Obesity is related to increased TNF-alpha production in different tissues. TNF-alpha is connected to mitochondrial dysfunction in the liver and also development of fatty infiltration of the liver. Also, postnatal change from normal to high-fat diet causes a significant increase in TNF-alpha serum levels. The aim of this research was to determine how maternal diet and switching male offspring to a different dietary regime after lactation influences rat liver. Ten female Sprague Dawley rats at nine weeks of age were randomly divided in two groups and fed either standard laboratory chow or high-fat diet during six weeks, and then mated with the same male subject. After birth and lactation male offspring from both groups were further divided into four subgroups depending on their subsequent diet. At 22 weeks of age, the animals were weighted, sacrificed and major organs were collected and weighted. Immunohistochemistry for TNF-alpha was performed on liver, and liver samples were analyzed for pathohistological changes. The group in which mothers were fed standard chow and offspring high-fat diet had the most pronounced changes: heaviest liver, poorest histopathological findings and strongest TNF-alpha immunohistochemical staining of liver parenchyma. High-fat diet during pregnancy and lactation and switching to high-fat diet postnatally affects liver weight, histological structure and TNF-alpha expression in male offspring. Copyright © 2017 Elsevier GmbH. All rights reserved.

  14. Iodine metabolism and thyroid functions in various species of domestic animals and poultry birds. I - Species difference in thyroid status as reflected by triiodothyronine 131I uptake test

    International Nuclear Information System (INIS)

    Setia, M.S.; Parshad, Omkar; Varman, P.N.

    1974-01-01

    In vitro triiodothyronine- 131 I uptake, by red blood cells was studied in buffaloes, buffaloe calves, cross-bred calves, rams, goats, piglets and also in pure white leg horn and cross-bred birds. Results revealed that buffalo calves have the lowest uptake values, whereas piglets appeared to have the highest values as compared to other species. Distinct differences in the uptake of T 3 - 131 I by the erythrocytes were observed to exist within as well as amongst the species of farm animals and poultry birds studied. Cross-breds exhibited higher degree of T 3 - 131 I uptake as compared to pure-breds. This test offers promise where more tedious methods may not be possible for conducting the survey on the thyroid status and iodine metabolism on large population of live-stock. (author)

  15. TRANSCRIPTOME ANALYSES REVEAL DIFFERENTIAL GENE EXPRESSION PATTERNS BETWEEN THE LIFE-CYCLE STAGES OF EMILIANIA HUXLEYI (HAPTOPHYTA) AND REFLECT SPECIALIZATION TO DIFFERENT ECOLOGICAL NICHES(1).

    Science.gov (United States)

    Rokitta, Sebastian D; de Nooijer, Lennart J; Trimborn, Scarlett; de Vargas, Colomban; Rost, Björn; John, Uwe

    2011-08-01

    Coccolithophores, especially the abundant, cosmopolitan species Emiliania huxleyi (Lohmann) W. W. Hay et H. P. Mohler, are one of the main driving forces of the oceanic carbonate pump and contribute significantly to global carbon cycling, due to their ability to calcify. A recent study indicates that termination of diploid blooms by viral infection induces life-cycle transition, and speculation has arisen about the role of the haploid, noncalcifying stage in coccolithophore ecology. To explore gene expression patterns in both life-cycle stages, haploid and diploid cells of E. huxleyi (RCC 1217 and RCC 1216) were acclimated to limiting and saturating photon flux densities. Transcriptome analyses were performed to assess differential genomic expression related to different ploidy levels and acclimation light intensities. Analyses indicated that life-cycle stages exhibit different properties of regulating genome expression (e.g., pronounced gene activation and gene silencing in the diploid stage), proteome maintenance (e.g., increased turnover of proteins in the haploid stage), as well as metabolic processing (e.g., pronounced primary metabolism and motility in the haploid stage and calcification in the diploid stage). Furthermore, higher abundances of transcripts related to endocytotic and digestive machinery were observed in the diploid stage. A qualitative feeding experiment indicated that both life-cycle stages are capable of particle uptake (0.5 μm diameter) in late-stationary growth phase. Results showed that the two life-cycle stages represent functionally distinct entities that are evolutionarily shaped to thrive in the environment they typically inhabit. © 2011 Phycological Society of America.

  16. Different temperature and cooling patterns at the blunt and sharp egg poles reflect the arrangement of eggs in an avian clutch.

    Science.gov (United States)

    Šálek, Miroslav E; Zárybnická, Markéta

    2015-01-01

    Incubation is an energetically demanding process during which birds apply heat to their eggs to ensure embryonic development. Parent behaviours such as egg turning and exchanging the outer and central eggs in the nest cup affect the amount of heat lost to the environment from individual eggs. Little is known, however, about whether and how egg surface temperature and cooling rates vary among the different areas of an egg and how the arrangement of eggs within the clutch influences heat loss. We performed laboratory (using Japanese quail eggs) and field (with northern lapwing eggs) experiments using infrared imaging to assess the temperature and cooling patterns of heated eggs and clutches. We found that (i) the sharp poles of individual quail eggs warmed to a higher egg surface temperature than did the blunt poles, resulting in faster cooling at the sharp poles compared to the blunt poles; (ii) both quail and lapwing clutches with the sharp poles oriented towards the clutch centre (arranged clutches) maintained higher temperatures over the central part of the clutch than occurred in those clutches where most of the sharp egg poles were oriented towards the exterior (scattered clutches); and (iii) the arranged clutches of both quail and lapwing showed slower cooling rates at both the inner and outer clutch positions than did the respective parts of scattered clutches. Our results demonstrate that egg surface temperature and cooling rates differ between the sharp and blunt poles of the egg and that the orientation of individual eggs within the nest cup can significantly affect cooling of the clutch as a whole. We suggest that birds can arrange their eggs within the nest cup to optimise thermoregulation of the clutch.

  17. Effect of x-ray treatments on pathogenic bacteria, inherent microbiota, color, and texture on parsley leaves.

    Science.gov (United States)

    Mahmoud, Barakat S M

    2012-10-01

    This work is a part of systematic studies of the effect of X-ray treatments on fresh produce. The main objective of this investigation was to study the effects of X-ray treatments in reducing the concentration of artificially inoculated Escherichia coli O157:H7, Listeria monocytogenes, Salmonella enterica, and Shigella flexneri, and inherent microbiota on parsley leaves. The secondary objective was to study the effects of X-ray treatments on color and texture parameters on treated parsley leaves. The Dip-inoculated method was used to inoculate parsley leaves with a mixture of two or three strains of each tested organism at 10(8) to 10(9) colony-forming unit (CFU)/mL; the inoculated parsley leaves were then air-dried and followed by treatment with different doses of X-ray (0, 0.1, 0.5, 1.0, and 1.5 kGy) at 22°C and 55-60% relative humidity. Surviving bacterial populations on parsley leaves were evaluated using a nonselective medium (tryptic soy agar) with a selective medium overlay for each bacterium: E. coli O157:H7 (CT-SMAC agar), L. monocytogenes (MOA), and S. enterica and S. flexneri (XLD). Approximately 5.8, 3.1, 5.7, and 5.2 log CFU reductions of E. coli O157:H7, L. monocytogenes, S. enterica, and Shigella flexneri were achieved by treatment with 1.0 kGy X-ray, respectively. Furthermore, the populations of E. coli O157:H7, L. monocytogenes, S. enterica, and Shigella flexneri were reduced to less than the detectable limit (1.0 log CFU/g) by treatment with 1.5 kGy X-ray. Treatment with 1.5 kGy X-ray significantly reduced the initial inherent microbiota on parsley leaves, and inherent levels were significantly (p 0.05) in color or texture of control and treated samples with 0.1-1.5 X-ray were observed. The results of investigation indicated that X-ray is an effective technology to eliminate E. coli O157:H7, L. monocytogenes, S. enterica, and Shigella flexneri, and to extend the shelf life of parsley leaves.

  18. 'My heart belongs to daddy'. Some reflections on the difference between generations as the organiser of the triangular structure of the mind.

    Science.gov (United States)

    Sapisochin, G

    1999-08-01

    The author begins his paper with a historical review of the concept of the difference between generations, which is in his opinion a metaphorical transformation that underpins the three-dimensional functioning of the psychic apparatus by introducing a differentiating intergenerational space between subject and object. He postulates that at the point of intersection between the intersubjective and the intrapsychic the subject clings to the specific fragments of his parents' history that are consistent with a belief about himself and the oedipal couple in which intergenerational links are severed and infantile incestuous wishes are seen as fulfilled. Disavowal of this generation gap is considered to lead to failure of post-oedipal secondary identifications, resulting in disturbance of the triangular structuring of the mind and consequent impairment of the genesis of thought processes. These ideas are compared with related conceptions of other authors and illustrated, with an account of the associated transference/countertransference vicissitudes, by a clinical example of the constellation the author calls 'My heart belongs to daddy', which he sees as a way station in the negotiation of the female Oedipus complex.

  19. Distinct enzyme profiles in patients with cryptogenic cirrhosis reflect heterogeneous causes with different outcomes after liver transplantation (OLT): a long-term documentation before and after OLT.

    Science.gov (United States)

    Berg, Thomas; Neuhaus, Ruth; Klein, Reinhild; Leder, Korinna; Lobeck, Hartmut; Bechstein, Wolf-Otto; Müller, Andrea R; Wiedenmann, Bertram; Hopf, Uwe; Berg, Peter A; Neuhaus, Peter

    2002-09-27

    Sound information is lacking about the clinical presentation of cryptogenic cirrhosis and its outcome after orthotopic liver transplantation (OLT). Among 856 patients who have been transplanted at our center, 40 patients had no evidence of any known etiologies and were therefore defined as suffering from cryptogenic cirrhosis. Their median follow-up period before OLT was 78 months (range, 1-264), and after OLT 97 months (range, 1-132). Laboratory and histological data were evaluated according to features being compatible either with a toxic, hepatitic, or cholestatic condition. The clinical and histological findings differed specifically between these three groups. The toxic-like group (GGT 4-18 x upper limit of normal [ULN]) expressed significantly higher IgA levels, had histologically more often fatty liver changes, and risk factors for non-alcoholic steatohepatitis predominated (56% compared with 3% in the other groups, P=0.01). The hepatitic-like group (ALT 2-18 x ULN) showed histologically features of chronic hepatitis or hepatitic cirrhosis, and only among these patients a median International Autoimmune Hepatitis (IAH) score of 13 was found suggesting autoimmune hepatitis (AiH). In the cholestatic group (AP 2-8 x ULN) histology was compatible with a non-toxic inflammatory process but IAH score excluded AiH in all. After OLT, actuarial graft and patients survival was 90% at 5 years. Mild or moderate graft hepatitis occurred in 9 patients (23%) and was significantly associated with a pre-OLT IAH score >or= 10 (P =0.008). This study provides arguments that cryptogenic cirrhosis is a heterogeneous disease in which autoimmune mechanisms might be predominately involved and being responsible for recurrence of chronic liver disease observed in some instances after OLT.

  20. Oxygen consumption rates in hovering hummingbirds reflect substrate-dependent differences in P/O ratios: carbohydrate as a 'premium fuel'.

    Science.gov (United States)

    Welch, Kenneth C; Altshuler, Douglas L; Suarez, Raul K

    2007-06-01

    The stoichiometric relationship of ATP production to oxygen consumption, i.e. the P/O ratio, varies depending on the nature of the metabolic substrate used. The latest estimates reveal a P/O ratio approximately 15% higher when glucose is oxidized compared with fatty acid oxidation. Because the energy required to produce aerodynamic lift for hovering is independent of the metabolic fuel oxidized, we hypothesized that the rate of oxygen consumption, VO2, should decline as the respiratory quotient, RQ (VCO2/VO2), increases from 0.71 to 1.0 as hummingbirds transition from a fasted to a fed state. Here, we show that hovering VO2 values in rufous (Selasphorus rufus) and Anna's hummingbirds (Calypte anna) are significantly greater when fats are metabolized (RQ=0.71) than when carbohydrates are used (RQ=1.0). Because hummingbirds gained mass during our experiments, making mass a confounding variable, we estimated VO2 per unit mechanical power output. Expressed in this way, the difference in VO2 when hummingbirds display an RQ=0.71 (fasted) and an RQ=1.0 (fed) is between 16 and 18%, depending on whether zero or perfect elastic energy storage is assumed. These values closely match theoretical expectations, indicating that a combination of mechanical power estimates and ;indirect calorimetry', i.e. the measurement of rates of gas exchange, enables precise estimates of ATP turnover and metabolic flux rates in vivo. The requirement for less oxygen when oxidizing carbohydrate suggests that carbohydrate oxidation may facilitate hovering flight in hummingbirds at high altitude.

  1. Deliberate practice theory: relevance, effort, and inherent enjoyment of music practice.

    Science.gov (United States)

    Hyllegard, Randy; Bories, Tamara L

    2008-10-01

    This study examined three assumptions of the theory of deliberate practice for practice playing music on an electronic keyboard. 40 undergraduate students, divided into two separate groups, practiced one of two music sequences and rated the relevance of practice for improving performance on the sequences, the amount of effort needed to learn the sequences, and the inherent enjoyment of practice sessions. Findings for each assumption were consistent with those suggested by theory but also showed that perceptions are affected by the amount of practice completed and performance of the skill.

  2. Inherently safe SNR shutdown system with Curie point controlled sensor/switch unit

    International Nuclear Information System (INIS)

    Mueller, K.; Norajitra, P.; Reiser, H.

    1987-02-01

    Inherent shutdown due to increase in the sodium temperature at the core outlet is triggered by interruption of the current supply to the electromagnet coupling of absorber elements via curie point controlled sensor/switch units. These switches are arranged above suitable fuel element positions and spatially independent of the shutdown elements. Compared with other similar systems very short response times are achieved. A prototype switch unit has already undergone extensive testing. These tests have confirmed that switching takes place in a very narrow temperature range. (orig./HP) [de

  3. The development of a small inherently safe homogeneous reactor for the production of medical isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Carlin, G.E.; Bonin, H.W., E-mail: george.carlin@rmc.ca [Royal Military College of Canada, Kingston, Ontario (Canada)

    2013-07-01

    The use of radioisotopes for various procedures in the health care industry has become one of the most important practices in medicine. New interest has been found in the use of liquid fueled nuclear reactors to produce these isotopes due to the ease of fuel processing and ability to efficiently use LEU as the fuel source. A version of this reactor is being developed at the Royal Military College of Canada to act as a successor to the SLOWPOKE-2 platform. The thermal hydraulic and transient characteristics of a 20 kWt version are being studied to verify inherent safety abilities. (author)

  4. On the inherent self-excited macroscopic randomness of chaotic three-body system

    OpenAIRE

    Liao, Shijun; Li, Xiaoming

    2014-01-01

    What is the origin of macroscopic randomness (uncertainty)? This is one of the most fundamental open questions for human being. In this paper, 10000 samples of reliable (convergent), multiple-scale (from 1.0E-60 to 100) numerical simulations of a chaotic three-body system indicate that, without any external disturbance, the microscopic inherent uncertainty (in the level of 1.0E-60) due to physical fluctuation of initial positions of the three-body system enlarges exponentially into macroscopi...

  5. Treatment of inherently unstable open or infected fractures by open wound management and external skeletal fixation.

    Science.gov (United States)

    Ness, M G

    2006-02-01

    To assess the use of external skeletal fixation with open wound management for the treatment of inherently unstable open or infected fractures in dogs. A retrospective review of 10 cases. Fracture stabilisation and wound management required only a single anaesthetic, and despite the challenging nature of these injuries, the final outcome was acceptable or good in every case. However, minor complications associated with the fixator pins were quite common, and two dogs developed complications which required additional surgery. Open management of wounds, even when bone was exposed, proved to be an effective technique, and external skeletal fixators were usually effective at maintaining stability throughout an inevitably extended fracture healing period.

  6. Multiformity of inherent randomicity and visitation density in n symbolic dynamics

    International Nuclear Information System (INIS)

    Zhang Yagang; Wang Changjiang

    2007-01-01

    The multiformity of inherent randomicity and visitation density in n symbolic dynamics will be clarified in this paper. These stochastic symbolic sequences bear three features. The distribution of frequency, inter-occurrence times and the alignment of two random sequences are amplified in detail. The features of visitation density in surjective maps presents catholicity and the catholicity in n letters randomicity has the same measure foundation. We hope to offer a symbolic platform that satisfies these stochastic properties and to attempt to study certain properties of DNA base sequences, 20 amino acids symbolic sequences of proteid structure, and the time series that can be symbolic in finance market et al

  7. Evaluation of retro-reflective coating performance by reflectance and perceived relative brightness measurements

    Energy Technology Data Exchange (ETDEWEB)

    Luse, Kaiva; Pausus, Anete; Karitans, Varis; Ozolins, Maris; Tukisa, Madara, E-mail: kaiva.luse@gmail.com [University of Latvia, Optometry and Vision Science Department, Kengaraga street 8, Riga LV-1063 (Latvia)

    2011-06-23

    Retro-reflective properties of six types and five different colors or retro-reflective materials were discussed in this paper. Reflectance optical indicatrix of samples was determined and compared to obtained psychophyisical data of perceived brightness of human observer. Microscopic structure of the retro-reflective active regions of RR's was studied. Statistically significant differences in reflectivity and brightness of various types and colors of RR's were found.

  8. Evaluation of retro-reflective coating performance by reflectance and perceived relative brightness measurements

    International Nuclear Information System (INIS)

    Luse, Kaiva; Pausus, Anete; Karitans, Varis; Ozolins, Maris; Tukisa, Madara

    2011-01-01

    Retro-reflective properties of six types and five different colors or retro-reflective materials were discussed in this paper. Reflectance optical indicatrix of samples was determined and compared to obtained psychophyisical data of perceived brightness of human observer. Microscopic structure of the retro-reflective active regions of RR's was studied. Statistically significant differences in reflectivity and brightness of various types and colors of RR's were found.

  9. Reflections on preventive medicine.

    Science.gov (United States)

    Miettinen, Olli S

    2014-10-01

    Having thought much about medicine in my career-long effort to understand it and the research for its advancement, I have come to views rather different form the now-prevailing ones in respect to what preventive medicine is about; what epidemiology is in relation to preventive medicine; what distinguishes preventive medicine in preventive healthcare at large; the relation of preventive medicine to public health; the concept of health promotion; and also the core principles of preventive medicine. All of these views I set forth in this article, for the readers' critical reflection. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. SVBR-75/100 multi-purpose modular inherent-safety fast reactor

    International Nuclear Information System (INIS)

    Dragunov, Yu.G.; Stepanov, V.S.; Klimov, N.N.; Dedul, A.V.; Zrodnokov, A.V.; Toshinsky, G.I.; Komlev, O.G.; Krushelnitsky, V.N.; Takh, S.M.

    2006-01-01

    In this century energy consumption, including electric power, will continue growing on a large scale especially in developing countries. Significant changes in electric power market needs are to be expected in the direction of decreasing and varying the capacity of power sources. To satisfy the expected growth of demand for electric power and to take a decision concerning the ways of further development of global power, including nuclear engineering, it is very important to continue the development of innovative concepts of nuclear power sources, which might successfully compete with alternative power technologies at the future power markets. The proposed nuclear power source (or in other words - reactor plant) of new generation is supposed: - to have small power capacity in the range of 10 - 100 MW (electric) and possibility of its multi-purpose application (independent nuclear power source for desalination installations and electricity supply, nuclear power plants (NPP) of various capacity and purpose; - to use modular principle of construction of NPP of various capacity on the basis of unified 'typical' reactor plants; - to have qualitatively new level of passive safety and possess properties of inherent safety, deterministically excluding any opportunity of severe accidents; - to have an opportunity to use different kinds of fuel and to work in various fuel cycles at various stages of development of nuclear power without change in the design. And also to have long (7-10 years, and in the long term 15-20 years) core life time and enrichment on U-235 not higher than 20 % (which is in compliance with recommendations of IAEA under non-proliferation condition); - to be completely factory-manufactured, and an opportunity of its safe transportation to and from the NPP site shall be provided. Unified multi-purpose reactor plant SVBR-75/100 (Lead-Bismuth Fast Reactor with equivalent electric power of 75 - 100 MW-e depending on the steam parameters) meets the set of the

  11. SU-F-J-47: Inherent Uncertainty in the Positional Shifts Determined by a Volumetric Cone Beam Imaging System

    International Nuclear Information System (INIS)

    Giri, U; Ganesh, T; Saini, V; Munshi, A; Sarkar, B; Mohanti, B

    2016-01-01

    Purpose: To quantify inherent uncertainty associated with a volumetric imaging system in its determination of positional shifts. Methods: The study was performed on an Elekta Axesse™ linac’s XVI cone beam computed tomography (CBCT) system. A CT image data set of a Penta- Guide phantom was used as reference image by placing isocenter at the center of the phantom.The phantom was placed arbitrarily on the couch close to isocenter and CBCT images were obtained. The CBCT dataset was matched with the reference image using XVI software and the shifts were determined in 6-dimensions. Without moving the phantom, this process was repeated 20 times consecutively within 30 minutes on a single day. Mean shifts and their standard deviations in all 6-dimensions were determined for all the 20 instances of imaging. For any given day, the first set of shifts obtained was kept as reference and the deviations of the subsequent 19 sets from the reference set were scored. Mean differences and their standard deviations were determined. In this way, data were obtained for 30 consecutive working days. Results: Tabulating the mean deviations and their standard deviations observed on each day for the 30 measurement days, systematic and random errors in the determination of shifts by XVI software were calculated. The systematic errors were found to be 0.03, 0.04 and 0.03 mm while random errors were 0.05, 0.06 and 0.06 mm in lateral, craniocaudal and anterio-posterior directions respectively. For rotational shifts, the systematic errors were 0.02°, 0.03° and 0.03° and random errors were 0.06°, 0.05° and 0.05° in pitch, roll and yaw directions respectively. Conclusion: The inherent uncertainties in every image guidance system should be assessed and baseline values established at the time of its commissioning. These shall be periodically tested as part of the QA protocol.

  12. Dynamics and inherent safety features of small modular high temperature gas-cooled reactors

    International Nuclear Information System (INIS)

    Harrington, R.M.; Ball, S.J.; Cleveland, J.C.

    1986-01-01

    Investigations were made at Oak Ridge National Laboratory to characterize the dynamics and inherent safety features of various modular high temperature gas-cooled reactor (HTGR) designs. This work was sponsored by the US Nuclear Regulatory Commission's HTGR Safety Research program. The US Department of Energy (DOE) and the Gas Cooled Reactor Associates (GCRA) have sponsored studies of several modular HTGR concepts, each having it own unique advantageous economic and inherent safety features. The DOE design team has recently choses a 350-MW(t) annular core with prismatic, graphite matrix fuel for its reference plant. The various safety features of this plant and of the pebble-bed core designs similar to those currently being developed and operated in the Federal Republic of Germany (FRG) are described. A varity of postulated accident sequences involving combinations of loss of forced circulation of the helium primary coolant, loss of primary coolant pressurization, and loss of normal and backup heat sinks were studied and are discussed. Results demonstrate that each concept can withstand an uncontrolled heatup accident without reaching excessive peak fuel temperatures. Comparisons of calculated and measured response for a loss of forced circulation test on the FRG reactor, AVR, are also presented. 10 refs

  13. DEM Simulation of Biaxial Compression Experiments of Inherently Anisotropic Granular Materials and the Boundary Effects

    Directory of Open Access Journals (Sweden)

    Zhao-Xia Tong

    2013-01-01

    Full Text Available The reliability of discrete element method (DEM numerical simulations is significantly dependent on the particle-scale parameters and boundary conditions. To verify the DEM models, two series of biaxial compression tests on ellipse-shaped steel rods are used. The comparisons on the stress-strain relationship, strength, and deformation pattern of experiments and simulations indicate that the DEM models are able to capture the key macro- and micromechanical behavior of inherently anisotropic granular materials with high fidelity. By using the validated DEM models, the boundary effects on the macrodeformation, strain localization, and nonuniformity of stress distribution inside the specimens are investigated using two rigid boundaries and one flexible boundary. The results demonstrate that the boundary condition plays a significant role on the stress-strain relationship and strength of granular materials with inherent fabric anisotropy if the stresses are calculated by the force applied on the wall. However, the responses of the particle assembly measured inside the specimens are almost the same with little influence from the boundary conditions. The peak friction angle obtained from the compression tests with flexible boundary represents the real friction angle of particle assembly. Due to the weak lateral constraints, the degree of stress nonuniformity under flexible boundary is higher than that under rigid boundary.

  14. INHERENT ASPECT: A SOCIOFUNCTIONALIST APPROACH OF PAST IMPERFECTIVE VERBAL FORMS IN SPANISH

    Directory of Open Access Journals (Sweden)

    Márluce Coan

    2014-03-01

    Full Text Available : We deal with the category aspect in a lexical dimension – an inherent aspect - and its interaction with the grammatical aspect, in order to inquire the convergences and divergences in the compositional shaping of the aspect. Our data come from twenty four short stories written in Spanish language, selected based on the cultural region parameter: Caribe; Mexico and Central America; Andes, Rio of the Prata; Chile and Spain. It was obtained a total of 2.093 data: 290 of them are imperfective periphrasis of past, that is, 13,85% of the total. These forms encode variably the descriptive, narrative, habitual and desiderative functions. The other identified functions – interactive, politeness, present, future, simultaneity, contrariety and playful – were only encoded by the imperfective past tense. The analysis of the correlation between the inherent aspect and the grammatical one corroborates the range of imperfectiviness by Givón (2001, which issupported by criteria of Vendler’s typology (2005 [1967]: states, the ones less marked and predicable, present more occurrences; followed at scale by activities, culminated processes, and culminations, the ones which are more marked and less predictable.

  15. INHERENT ASPECT: A SOCIOFUNCTIONALIST APPROACH OF PAST IMPERFECTIVE VERBAL FORMS IN SPANISH

    Directory of Open Access Journals (Sweden)

    Márluce COAN

    2013-12-01

    Full Text Available We deal with the category aspect in a lexical dimension – an inherent aspect - and its interaction with the grammatical aspect, in order to inquire the convergences and divergences in the compositional shaping of the aspect. Our data come from twenty four short stories written in Spanish language, selected based on the cultural region parameter: Caribe; Mexico and Central America; Andes, Rio of the Prata; Chile and Spain. It was obtained a total of 2.093 data: 290 of them are imperfective periphrasis of past, that is, 13,85% of the total. These forms encode variably the descriptive, narrative, habitual and desiderative functions. The other identified functions – interactive, politeness, present, future, simultaneity, contrariety and playful – were only encoded by the imperfective past tense. The analysis of the correlation between the inherent aspect and the grammatical one corroborates the range of imperfectiviness by Givón (2001, which issupported by criteria of Vendler’s typology (2005 [1967]: states, the ones less marked and predicable, present more occurrences; followed at scale by activities, culminated processes, and culminations, the ones which are more marked and less predictable.

  16. Optimal control of quantum systems: Origins of inherent robustness to control field fluctuations

    International Nuclear Information System (INIS)

    Rabitz, Herschel

    2002-01-01

    The impact of control field fluctuations on the optimal manipulation of quantum dynamics phenomena is investigated. The quantum system is driven by an optimal control field, with the physical focus on the evolving expectation value of an observable operator. A relationship is shown to exist between the system dynamics and the control field fluctuations, wherein the process of seeking optimal performance assures an inherent degree of system robustness to such fluctuations. The presence of significant field fluctuations breaks down the evolution of the observable expectation value into a sequence of partially coherent robust steps. Robustness occurs because the optimization process reduces sensitivity to noise-driven quantum system fluctuations by taking advantage of the observable expectation value being bilinear in the evolution operator and its adjoint. The consequences of this inherent robustness are discussed in the light of recent experiments and numerical simulations on the optimal control of quantum phenomena. The analysis in this paper bodes well for the future success of closed-loop quantum optimal control experiments, even in the presence of reasonable levels of field fluctuations

  17. Inherent safety features of the HTTR revealed in the accident condition

    International Nuclear Information System (INIS)

    Kunitomi, K.; Shinozaki, M.; Baba, O.; Saito, S.

    1992-01-01

    The High Temperature Engineering Test Reactor (HTTR) being constructed by JAERI (Japan Atomic Energy Research Institute) is a graphite-moderated and helium-cooled reactor with an outlet gas temperature of 950degC. The inherent safety characteristics in the HTTR prevent temperature increase of reactor fuels and fission product release from the reactor core in postulated accident conditions. The reactor core can be cooled by a Vessel Cooling System (VCS) indirectly, even in the case that no forced cooling is expected during the accident such as primary pipe break. The VCS consists of independent water cooling loop and cooling panel around the reactor pressure vessel. The cooling panel whose temperature of 60-90degC cools the reactor pressure vessel by radiation and removes the decay heat from the core indirectly. Furthermore, even if failure of VCS is assumed during this accident as a severe accident, the reactor core is remained safe despite the temperature increase of biological concrete shield around the reactor pressure vessel. This paper describes the inherent safety features of the HTTR specially focused on the accident condition without forced cooling. The detailed analytical results of such an accident are described together with clarifying the role of the VCS. (author)

  18. The development of an inherent safety approach to the prevention of domino accidents.

    Science.gov (United States)

    Cozzani, Valerio; Tugnoli, Alessandro; Salzano, Ernesto

    2009-11-01

    The severity of industrial accidents in which a domino effect takes place is well known in the chemical and process industry. The application of an inherent safety approach for the prevention of escalation events leading to domino accidents was explored in the present study. Reference primary scenarios were analyzed and escalation vectors were defined. Inherent safety distances were defined and proposed as a metric to express the intensity of the escalation vectors. Simple rules of thumb were presented for a preliminary screening of these distances. Swift reference indices for layout screening with respect to escalation hazard were also defined. Two case studies derived from existing layouts of oil refineries were selected to understand the potentialities coming from the application in the methodology. The results evidenced that the approach allows a first comparative assessment of the actual domino hazard in a layout, and the identification of critical primary units with respect to escalation events. The methodology developed also represents a useful screening tool to identify were to dedicate major efforts in the design of add-on measures, optimizing conventional passive and active measures for the prevention of severe domino accidents.

  19. Synthesis and Characterization of Pure Copper Nanostructures Using Wood Inherent Architecture as a Natural Template

    Science.gov (United States)

    Dong, Youming; Wang, Kaili; Tan, Yi; Wang, Qingchun; Li, Jianzhang; Mark, Hughes; Zhang, Shifeng

    2018-04-01

    The inherent sophisticated structure of wood inspires researchers to use it as a natural template for synthesizing functional nanoparticles. In this study, pure copper nanoparticles were synthesized using poplar wood as a natural inexpensive and renewable template. The crystal structure and morphologies of the copper nanoparticles were characterized by X-ray diffraction and field emission scanning electron microscopy. The optical properties, antibacterial properties, and stability of the hybrid wood materials were also tested. Due to the hierarchical and anisotropic structure and electron-rich components of wood, pure copper nanoparticles with high stability were synthesized with fcc structure and uniform sizes and then assembled into corncob-like copper deposits along the wood cell lumina. The products of nanoparticles depended strongly on the initial OH- concentration. With an increase in OH- concentration, Cu2O gradually decreased and Cu remained. Due to the restrictions inherent in wood structure, the derived Cu nanoparticles showed similar grain size in spite of increased Cu2+ concentration. This combination of Cu nanostructures and wood exhibited remarkable optical and antibacterial properties.

  20. Effective material parameter retrieval of anisotropic elastic metamaterials with inherent nonlocality

    Science.gov (United States)

    Lee, Hyung Jin; Lee, Heung Son; Ma, Pyung Sik; Kim, Yoon Young

    2016-09-01

    In this paper, the scattering (S-) parameter retrieval method is presented specifically for anisotropic elastic metamaterials; so far, no retrieval has been accomplished when elastic metamaterials exhibit fully anisotropic behavior. Complex constitutive property and intrinsic scattering behavior of elastic metamaterials make their characterization far more complicated than that for acoustic and electromagnetic metamaterials. In particular, elastic metamaterials generally exhibit anisotropic scattering behavior due to higher scattering modes associated with shear deformation. They also exhibit nonlocal responses to some degrees, which originate from strong multiple scattering interactions even in the long wavelength limit. Accordingly, the conventional S-parameter retrieval methods cannot be directly used for elastic metamaterials, because they determine only the diagonal components in effective tensor property. Also, the conventional methods simply use the analytic inversion formulae for the material characterization so that inherent nonlocality cannot be taken into account. To establish a retrieval method applicable to anisotropic elastic metamaterials, we propose an alternative S-parameter method to deal with full anisotropy of elastic metamaterials. To retrieve the whole effective anisotropic parameter, we utilize not only normal but also oblique wave incidences. For the retrieval, we first retrieve the ratio of the effective stiffness tensor to effective density and then determine the effective density. The proposed retrieval method is validated by characterizing the effective material parameters of various types of non-resonant anisotropic metamaterials. It is found that the whole effective parameters are retrieved consistently regardless of used retrieval conditions in spite of inherent nonlocality.

  1. A fiberoptic reflection oximeter.

    Science.gov (United States)

    Landsman, M L; Knop, N; Kwant, G; Mook, G A; Zijlstra, W G

    1978-03-20

    A catheter tip oximeter is described consisting of a cardiac catheter containing optical fibers, and incandescent light source, a light detection unit and a processing unit. Half of the optical fibers guide the light to the blood at the tip of the catheter, the other half the backscattered (reflected) light to the detection unit. The detection unit contains a dichroic mirror, transmitting most of the light with lambda less than 800 nm and reflecting most of the light with lambda greater than 900 nm, thus splitting the light into two beams. These pass through interference filters with nominal wavelengths of 640 and 920 nm respectively, and are focused on silicium barrier layer photocells. The photocell signals are amplified and fed into a divider giving the ratio of measuring (R640) and compensating (R920) photocell output. The relationship between log R640/R920 and oxygen saturation is represented by a slightly curved line. The relation may be linearized by subtracting a constant voltage from the divided output before taking the logarithm. The slope of the calibration line is dependent on the total haemoglobin concentration. Nonetheless an average calibration line can be used between 70 and 100% oxygen saturation. For 78 measurements of pig blood samples in this range (haemoglobin concentration between 96 and 161 g.1(-1)), the standard deviation of the difference between the fiberoptic oximeter and a Radiometer OSM1 oxygen saturation meter was 1.9% saturation, for 152 samples over the entire saturation range the standard deviation of the difference was 3.1% saturation. The influence of the flow velocity of blood on the light reflection depends on wavelength as well as on oxygen saturation. Therefore, complete compensation for the flow effect is not possible by simple means.

  2. Monitoring phenology of photosynthesis in temperate evergreen and mixed deciduous forests using the normalized difference vegetation index (NDVI) and the photochemical reflectance index (PRI) at leaf and canopy scales

    Science.gov (United States)

    Wong, C. Y.; Arain, M. A.; Ensminger, I.

    2016-12-01

    Evergreen conifers in boreal and temperate regions undergo strong seasonal changes in photoperiod and temperatures, which determines their phenology of high photosynthetic activity in the growing season and downregulation during the winter. Monitoring the timing of the transition between summer activity and winter downregulation in evergreens is difficult since this is a largely invisible process, unlike in deciduous trees that have a visible budding and a sequence of leaf unfolding in the spring and leaf abscission in the fall. The light-use efficiency (LUE) model estimates gross primary productivity (GPP) and may be parameterized using remotely sensed vegetation indices. Using spectral reflectance data, we derived the normalized difference vegetation index (NDVI), a measure of leaf "greenness", and the photochemical reflectance index (PRI), a proxy for chlorophyll:carotenoid ratios which is related to photosynthetic activity. To better understand the relationship between these vegetation indices and photosynthetic activity and to contrast this relationship between plant functional types, the phenology of NDVI, PRI and photosynthesis was monitored in an evergreen forest and a mixed deciduous forest at the leaf and canopy scale. Our data indicates that the LUE model can be parameterized by NDVI and PRI to track forest phenology. Differences in the sensitivity of PRI and NDVI will be discussed. These findings have implications to address the phenology of evergreen conifers by using PRI to complement NDVI in the LUE model, potentially improving model productivity estimates in northern hemisphere forests, that are dominated by conifers.

  3. Mexico's four economies reflect regional differences, challenges

    OpenAIRE

    Canas, Jesus; Gutierrez, Emily

    2015-01-01

    The economic potential of Mexico’s four regions is defined by their industrial makeup, income per capita and how much of the labor force operates outside the formal economy. Recent government reforms could promote growth and reduce regional inequality.

  4. A new radiative transfer scattering phase function discretisation approach with inherent energy conservation

    CSIR Research Space (South Africa)

    Roos, TH

    2014-06-01

    Full Text Available large sphere scattering phase function distributions of interest for packed bed radiative heat transfer: the analytic distribution for a diffusely reflecting sphere (a backscattering test case) and the distribution for a transparent sphere (n = 1...

  5. The Absolute Reflectance and New Calibration Site of the Moon

    Science.gov (United States)

    Wu, Yunzhao; Wang, Zhenchao; Cai, Wei; Lu, Yu

    2018-05-01

    How bright the Moon is forms a simple but fundamental and important question. Although numerous efforts have been made to answer this question such as use of sophisticated electro-optical measurements and suggestions for calibration sites, the answer is still debated. An in situ measurement with a calibration panel on the surface of the Moon is crucial for obtaining the accurate absolute reflectance and resolving the debate. China’s Chang’E-3 (CE-3) “Yutu” rover accomplished this type of measurement using the Visible-Near Infrared Spectrometer (VNIS). The measurements of the VNIS, which were at large emission and phase angles, complement existing measurements for the range of photometric geometry. The in situ reflectance shows that the CE-3 landing site is very dark with an average reflectance of 3.86% in the visible bands. The results are compared with recent mission instruments: the Lunar Reconnaissance Orbiter Camera (LROC) Wide Angle Camera (WAC), the Spectral Profiler (SP) on board the SELENE, the Moon Mineralogy Mapper (M3) on board the Chandrayaan-1, and the Chang’E-1 Interference Imaging Spectrometer (IIM). The differences in the measurements of these instruments are very large and indicate inherent differences in their absolute calibration. The M3 and IIM measurements are smaller than LROC WAC and SP, and the VNIS measurement falls between these two pairs. When using the Moon as a radiance source for the on-orbit calibration of spacecraft instruments, one should be cautious about the data. We propose that the CE-3 landing site, a young and homogeneous surface, should serve as the new calibration site.

  6. [The Ability to Successfully Perform Different Kinds of Cognitive Activity Is Reflected in the Topological Features of Intracortical Interactions (Sex Differences in Boys and Girls Aged 5-6 Years)].

    Science.gov (United States)

    Panasevich, E A; Tsitseroshin, M N

    2015-01-01

    We studied the correlation of intellectual development according to The Wechsler Intelligence Scale for Children (WISC test) with the spatial organization of resting EEG in 52 children aged 5-6 years. It was found that the patterns of interregional interactions of different parts of the cortex which correspond with the best performance in the subtests in boys (n = 23) and girls (n = 29) have significant topological differences. In girls, successful subtest performance positively correlated to a greater extent with interhemispheric interactions; in boys--long longitudinal rostral-caudal interactions between various regions of the cortex. The results showed that there are important gender differences in the spatial organization of brain activity associated with the performance of different cognitive activities in preschool children. The successful performance of various subtests by boys required considerable variability in the organization of spatial patterns of interregional interactions; on the contrary, the spatial structure of these patterns in girls was relatively invariable. Obviously, for the successful performance of various cognitive activities at this age in boys, the cortex need to form highly specialized organization of intracortical interactions, while in girls the brain uses relatively similar reorganization of interactions. The data suggest that 5-6-year-old boys and girls use different cognitive strategies when performing the same subtests of the WISC test.

  7. The Reflective Methodologists

    DEFF Research Database (Denmark)

    Kjær, Bjørg

    2013-01-01

    In recent years, a focus on inclusion and vulnerable children has reignited discussions about the quality of pedagogical work. It has also initiated processes of change that have challenged the Danish kindergarten tradition and the identity of the pedagogue in a number of different ways. In this ......In recent years, a focus on inclusion and vulnerable children has reignited discussions about the quality of pedagogical work. It has also initiated processes of change that have challenged the Danish kindergarten tradition and the identity of the pedagogue in a number of different ways...... in which the practical sense and tacit knowledge are related to questions of power and social actors’ strategies for positioning themselves within a social space. This demands a particular focus on the historical effect of the concept of ‘the reflective practitioner’ as a symbolic marker of identity...

  8. Superconvergent sum rules for the normal reflectivity

    International Nuclear Information System (INIS)

    Furuya, K.; Zimerman, A.H.; Villani, A.

    1976-05-01

    Families of superconvergent relations for the normal reflectivity function are written. Sum rules connecting the difference of phases of the reflectivities of two materials are also considered. Finally superconvergence relations and sum rules for magneto-reflectivity in the Faraday and Voigt regimes are also studied

  9. European Constitutional Identity “Inside Out”: Inherent Risks of the Pluralist Structure

    DEFF Research Database (Denmark)

    Cebulak, Pola Paula

    2012-01-01

    The jurisprudence of the CJEU and the national constitutional courts referring to the national constitutional identities of the Members States fits into the framework of constitutional pluralism as modus vivendi of the European legal order. This paper focuses in particular on the recent judgments...... the tensions inherent in the pluralist structure of the relationships between legal orders in the European arena. Constitutional identity is yet another concept used in this debate about the ultimate authority. Pluralism assumes that the courts will compete over the ultimate authority and will try to use...... for fruitful interaction of competing visions of Europe. Single criticisable judgments do not put in question the viability of the whole framework, but it is important to be aware of the systemic risks....

  10. Evaluation of design variants for improved inherent regulation of advanced small modular reactors - 15325

    International Nuclear Information System (INIS)

    Vilim, R.B.; Passerini, S.

    2015-01-01

    This paper examines design variants that can improve inherent regulation in Advanced Small Modular Reactors (ASMR). It looks at the nature of unprotected upsets and then develops appropriate design measures to ensure that no upset can override a capability for safe self-regulation. This work adopts a reference sodium fast reactor (SFR) design to serve as a baseline for operational and safety performance and for comparison with variants on this design. The effect of design measures on plant stability is then examined. It is found that compared to full-power operation, the stability margin is reduced under islanded-operation. Islanded-operation is more likely for an ASMR deployed in a small regional electric grid with high penetration of renewable energy sources. The stability of core power production is a function of the inlet temperature coefficient, coolant transport times, and temperature-front attenuation in heat exchangers. The interaction of these phenomena with the control system is described

  11. Design of a Single Motor Based Leg Structure with the Consideration of Inherent Mechanical Stability

    Science.gov (United States)

    Taha Manzoor, Muhammad; Sohail, Umer; Noor-e-Mustafa; Nizami, Muhammad Hamza Asif; Ayaz, Yasar

    2017-07-01

    The fundamental aspect of designing a legged robot is constructing a leg design that is robust and presents a simple control problem. In this paper, we have successfully designed a robotic leg based on a unique four bar mechanism with only one motor per leg. The leg design parameters used in our platform are extracted from design principles used in biological systems, multiple iterations and previous research findings. These principles guide a robotic leg to have minimal mechanical passive impedance, low leg mass and inertia, a suitable foot trajectory utilizing a practical balance between leg kinematics and robot usage, and the resultant inherent mechanical stability. The designed platform also exhibits the key feature of self-locking. Theoretical tools and software iterations were used to derive these practical features and yield an intuitive sense of the required leg design parameters.

  12. On the fundamentals of nuclear reactor safety assessment. Inherent threats and their implications

    Energy Technology Data Exchange (ETDEWEB)

    Hyvaerinen, J. [Finnish Centre for Radiation and Nuclear Safety, Helsinki (Finland). Nuclear Safety Dept.

    1996-12-01

    The thesis addresses some fundamental questions related to implementation and assessment of nuclear safety. The safety principles and assessment methods are described, followed by descriptions of selected novel technical challenges to nuclear safety. The novel challenges encompass a wide variety of technical issues, thus providing insights on the limitations of conventional safety assessment methods. Study of the limitations suggests means to improve nuclear reactor design criteria and safety assessment practices. The novel safety challenges discussed are (1) inherent boron dilution in PWRs, (2) metallic insulation performance with respect to total loss of emergency cooling systems in a loss-of-coolant accident, and (3) horizontal steam generator heat transfer performance at natural circulation conditions. (50 refs.).

  13. Utopia and Debt in Postmodernity; or, Time Management in Inherent Vice

    Directory of Open Access Journals (Sweden)

    James Liner

    2016-05-01

    Full Text Available The category of postmodernism has come under renewed scrutiny in recent years. Indeed, it has become rather commonplace to pronounce the death or obsolescence of postmodernism today. Unsurprisingly, the increasingly questioned status of postmodernism also impacts the field of Pynchon studies. This article reads 'Inherent Vice' as symptomatic not of the end but of a transformation of postmodernism and postmodernity. Pynchon’s novel simultaneously registers a contemporary intensification of postmodern/late capitalism and, crucially, participates in a minor current in postmodernism, one which insists on collective agency and utopian thinking despite the atomization and isolation of subjects accomplished by late capitalism and which, against all odds, remembers how to think historically—or better, invents new ways of thinking historically.

  14. A level III PSA for the inherently safe CAREM-25 nuclear power station

    International Nuclear Information System (INIS)

    Baron, Jorge H.; Nunez McLeod, J.; Rivera, S.S.

    2000-01-01

    A Level III PSA has been performed for the inherently safe CAREM-25 nuclear power station, as a requirement for licensing according to argentinian regulations. The CAREM-25 project is still at a detailed design state, therefore only internal events have been considered, and a representative site has been assumed for dose estimations. Several conservative hypothesis have been formulated, but even so an overall core melt frequency of 2.3E -5 per reactor year has been obtained. The risk estimations comply with the regulations. The risk values obtained are compared to the 700MW(e) nuclear power plant Atucha II PSA result, showing an effective risk reduction not only in the severe accident probability but alto in the consequence component of the risk estimation. (author)

  15. Why infest the loved ones--inherent human behaviour indicates former mutualism with head lice.

    Science.gov (United States)

    Rózsa, Lajos; Apari, Péter

    2012-05-01

    Head lice transmit to new hosts when people lean their heads together. Humans frequently touch their heads to express friendship or love, while this behaviour is absent in apes. We hypothesize that this behaviour was adaptive because it enabled people to acquire head lice infestations as early as possible to provoke an immune response effective against both head lice and body lice throughout the subsequent periods of their life. This cross-immunity could provide some defence against the body-louse-borne lethal diseases like epidemic typhus, trench fever, relapsing fever and the classical plague. Thus the human 'touching heads' behaviour probably acts as an inherent and unconscious 'vaccination' against body lice to reduce the threat exposed by the pathogens they may transmit. Recently, the eradication of body-louse-borne diseases rendered the transmission of head lice a maladaptive, though still widespread, behaviour in developed societies.

  16. Inherently safe aircooling for the storage of self-heating configurations of radionuclides

    International Nuclear Information System (INIS)

    Hame, W.; Klein, D.; Pirk, H.

    1980-01-01

    NUKEM developed a technical concept of a radionuclide storage facility based on aircooling, which provides that - the radionuclides, i.e. spent fuel elements, are tightly canned in steel canisters - the canned elements are put into individual cooling channels, which form the storage rack within the storage cell - the produced heat is removed from the surface of the canisters through free convection. This cooling concept shows the following advantages: - The cooling is inherently safe, as the driving force of the coolant is reliably supplied by the heat production of the system to be cooled. - The system is self-controlled and self-regulated because of the physically based correlation of heat production, heat transfer coefficients and air flow resistances. (orig.) 891 RB/orig. 892 MKO [de

  17. On the fundamentals of nuclear reactor safety assessment. Inherent threats and their implications

    International Nuclear Information System (INIS)

    Hyvaerinen, J.

    1996-12-01

    The thesis addresses some fundamental questions related to implementation and assessment of nuclear safety. The safety principles and assessment methods are described, followed by descriptions of selected novel technical challenges to nuclear safety. The novel challenges encompass a wide variety of technical issues, thus providing insights on the limitations of conventional safety assessment methods. Study of the limitations suggests means to improve nuclear reactor design criteria and safety assessment practices. The novel safety challenges discussed are (1) inherent boron dilution in PWRs, (2) metallic insulation performance with respect to total loss of emergency cooling systems in a loss-of-coolant accident, and (3) horizontal steam generator heat transfer performance at natural circulation conditions. (50 refs.)

  18. Analysis Relationship Among Descriptor, References and Citation to Contruct the Inherent Structure of Document Collection

    International Nuclear Information System (INIS)

    Hasibuan, Zainal A.; Mustangimah

    2001-01-01

    There are many characteristics can be used to identify a document which cover characteristics of the documents, cited documents, and citing documents This research explored the inherent structure of a document collection as one of main components of information retrieval system. The characteristics examined are: descriptors, references (cited documents), and citations (citing documents). Three independent variables were studied: co-descriptor, bibliographic coupling, and co-citation. A test collection was constructed by searching on a single descriptor i nformation retrieval i n the CD-ROM version of Education Resource Information Clearinghouse (ERIC), covering the period 1981 through 1985. Descriptors were extracted from ERIC; cited and citing documents associated with the test collection were derived from Social Sciences Citation Index (SSCI), covering the period 1981 through 1990. Three hypothesis were tested in this study, that are: (1) the higher the frequency of co-descriptors between documents, the higher the frequencies of their bibliographic coupling and co-citation; (2) the higher the frequency of bibliographic coupling between documents, the higher the frequencies of their co-citation and co-descriptors; and (3) the higher the frequency of co-citation between documents, the higher the frequencies of their co-descriptors and bibliographic coupling. The results showed that all of three hypothesis are supported statistically and there is a significant linear relationship among the observed variables. It is mean that there is a significant relationship among descriptors, references, and citation, so that it can be used to construct the inherent structure of document collection in order to improve information retrieval system performance

  19. Seeds of Brassicaceae weeds have an inherent or inducible response to the germination stimulant karrikinolide.

    Science.gov (United States)

    Long, Rowena L; Stevens, Jason C; Griffiths, Erin M; Adamek, Markus; Gorecki, Marta J; Powles, Stephen B; Merritt, David J

    2011-10-01

    Karrikinolide (KAR(1)) is a smoke-derived chemical that can trigger seeds to germinate. A potential application for KAR(1) is for synchronizing the germination of weed seeds, thereby enhancing the efficiency of weed control efforts. Yet not all species germinate readily with KAR(1), and it is not known whether seemingly non-responsive species can be induced to respond. Here a major agronomic weed family, the Brassicaceae, is used to test the hypothesis that a stimulatory response to KAR(1) may be present in physiologically dormant seeds but may not be expressed under all circumstances. Seeds of eight Brassicaceae weed species (Brassica tournefortii, Raphanus raphanistrum, Sisymbrium orientale, S. erysimoides, Rapistrum rugosum, Lepidium africanum, Heliophila pusilla and Carrichtera annua) were tested for their response to 1 µm KAR(1) when freshly collected and following simulated and natural dormancy alleviation, which included wet-dry cycling, dry after-ripening, cold and warm stratification and a 2 year seed burial trial. Seven of the eight Brassicaceae species tested were stimulated to germinate with KAR(1) when the seeds were fresh, and the remaining species became responsive to KAR(1) following wet-dry cycling and dry after-ripening. Light influenced the germination response of seeds to KAR(1), with the majority of species germinating better in darkness. Germination with and without KAR(1) fluctuated seasonally throughout the seed burial trial. KAR(1) responses are more complex than simply stating whether a species is responsive or non-responsive; light and temperature conditions, dormancy state and seed lot all influence the sensitivity of seeds to KAR(1), and a response to KAR(1) can be induced. Three response types for generalizing KAR(1) responses are proposed, namely inherent, inducible and undetected. Given that responses to KAR(1) were either inherent or inducible in all 15 seed lots included in this study, the Brassicaceae may be an ideal target for

  20. PRISM [Power Reactor Inherently Safe Module] design concept enhances waste management

    International Nuclear Information System (INIS)

    Thompson, M.L.; Berglund, R.C.

    1989-01-01

    PRISM, a modular advanced liquid metal reactor (ALMR), has been designed conceptually by GE under the US Department of Energy sponsorship. The concept design and analyses have been primarily focused on passive safety and improved construction and operating costs. Significantly, the unique design of multiple modules and features of PRISM enhance waste management over conventional reactor systems. This paper provides an overview of PRISM of these enhancements. Inherent to the ALMR's, the sodium coolant precludes crud buildup on reactor surfaces and in components and waste for disposal. Preliminary evaluations indicate this fundamental feature results in factors of 2-4 less waste volume and 2-3 orders of magnitude less curies per megawatt-electric for ultimate disposal. For example, the tap designed for sodium cleanup is expected to be exchanged only once every thirty years. Also, inherent to ALMR's, burning waste actinides and selected fission products to preclude their accumulation and burial is very attractive. The hard neutron spectrum of ALMR burns the actinides efficiently and is not poisoned by the actinides and fission products. The modular design of PRISM components (and the fuel cycle equipment) permit replacement without expensive and potentially hazardous volume reduction. For example, the functional components of the reference electromagnetic pump and IHK can be removed intact for waste disposal. Although development of the reference metal fuel is not completed, it is estimated that (low-level) waste from recycle of the fuel will result in significantly less volume than would be generated by aqueous recycle of oxide fuel. 6 refs., 10 figs

  1. Temperature-reflection I

    DEFF Research Database (Denmark)

    McGady, David A.

    2017-01-01

    -temperature path integrals for quantum field theories (QFTs) should be T-reflection invariant. Because multi-particle partition functions are equal to Euclidean path integrals for QFTs, we expect them to be T-reflection invariant. Single-particle partition functions though are often not invariant under T......In this paper, we revisit the claim that many partition functions are invariant under reflecting temperatures to negative values (T-reflection). The goal of this paper is to demarcate which partition functions should be invariant under T-reflection, and why. Our main claim is that finite...... that T-reflection is unrelated to time-reversal. Finally, we study the interplay between T-reflection and perturbation theory in the anharmonic harmonic oscillator in quantum mechanics and in Yang-Mills in four-dimensions. This is the first in a series of papers on temperature-reflections....

  2. Matter reflects Antimatter

    CERN Document Server

    Bianconi, A.; Cristiano, A.; Leali, M.; Lodi Rizzini, E.; Venturelli, L.; Zurlo, N.

    2008-01-01

    It is common belief that the interaction between antimatter and ordinary solid matter is dominated by annihilation. However, non-destructive processes may play a relevant role too. One century ago E. Rutherford wrote about the "diffuse reflection" of alpha and beta particles by thin layers of different metals: "The observations ... of Geiger and Marsden on the scattering of alpha rays indicate that some of the alpha particles must suffer a deflexion of more than a right angle at a single encounter.... It will be shown that the main deductions from the theory are independent of whether the central charge is supposed to be positive or negative". Although the theory of electromagnetic scattering is in first approximation independent of the relative sign of the colliding particles, in the case where projectile antiprotons are shot against a wall of solid matter the Rutherford diffuse reflection mechanism competes with the annihilation process. So it is not obvious at all that a relevant part of an antiproton beam...

  3. Liberating Moral Reflection

    Science.gov (United States)

    Horell, Harold D.

    2013-01-01

    The author argues that if we are to foster life-giving and liberating moral reflection, we must first liberate moral reflection from distortions; specifically, from the distorting effects of moral insensitivity, destructive moral relativism, and confusions resulting from a failure to understand the dynamics of moral reflection. The author proposes…

  4. Selecting Molecular Recognition. What Can Existing Aptamers Tell Us about Their Inherent Recognition Capabilities and Modes of Interaction?

    Directory of Open Access Journals (Sweden)

    Ralf Landgraf

    2012-05-01

    Full Text Available The use of nucleic acid derived aptamers has rapidly expanded since the introduction of SELEX in 1990. Nucleic acid aptamers have demonstrated their ability to target a broad range of molecules in ways that rival antibodies, but advances have been very uneven for different biochemical classes of targets, and clinical applications have been slow to emerge. What sets different aptamers apart from each other and from rivaling molecular recognition platforms, specifically proteins? What advantages do aptamers as a reagent class offer, and how do the chemical properties and selection procedures of aptamers influence their function? Do the building blocks of nucleic acid aptamers dictate inherent limitations in the nature of molecular targets, and do existing aptamers give us insight in how these challenges might be overcome? This review is written as an introduction for potential endusers of aptamer technology who are evaluating the advantages of aptamers as a versatile, affordable, yet highly expandable platform to target a broad range of biological processes or interactions.

  5. Identification of Phytoplankton Blooms under the Index of Inherent Optical Properties (IOP Index in Optically Complex Waters

    Directory of Open Access Journals (Sweden)

    Jesús A. Aguilar-Maldonado

    2018-01-01

    Full Text Available Phytoplankton blooms are sporadic events in time and are isolated in space. This complex phenomenon is produced by a variety of both natural and anthropogenic causes. Early detection of this phenomenon, as well as the classification of a water body under conditions of bloom or non-bloom, remains an unresolved problem. This research proposes the use of Inherent Optical Properties (IOPs in optically complex waters to detect the bloom or non-bloom state of the phytoplankton community. An IOP index is calculated from the absorption coefficients of the colored dissolved organic matter (CDOM, the phytoplankton (phy and the detritus (d, using the wavelength (λ 443 nm. The effectiveness of this index is tested in five bloom events in different places and with different characteristics from Mexican seas: 1. Dzilam (Caribbean Sea, Atlantic Ocean, a diatom bloom (Rhizosolenia hebetata; 2. Holbox (Caribbean Sea, Atlantic Ocean, a mixed bloom of dinoflagellates (Scrippsiella sp. and diatoms (Chaetoceros sp.; 3. Campeche Bay in the Gulf of Mexico (Atlantic Ocean, a bloom of dinoflagellates (Karenia brevis; 4. Upper Gulf of California (UGC (Pacific Ocean, a diatom bloom (Coscinodiscus and Pseudo-nitzschia and 5. Todos Santos Bay, Ensenada (Pacific Ocean, a dinoflagellate bloom (Lingulodinium polyedrum. The diversity of sites show that the IOP index is a suitable method to determine the phytoplankton bloom conditions.

  6. Safety assessment in plant layout design using indexing approach: implementing inherent safety perspective. Part 2-Domino Hazard Index and case study.

    Science.gov (United States)

    Tugnoli, Alessandro; Khan, Faisal; Amyotte, Paul; Cozzani, Valerio

    2008-12-15

    The design of layout plans requires adequate assessment tools for the quantification of safety performance. The general focus of the present work is to introduce an inherent safety perspective at different points of the layout design process. In particular, index approaches for safety assessment and decision-making in the early stages of layout design are developed and discussed in this two-part contribution. Part 1 (accompanying paper) of the current work presents an integrated index approach for safety assessment of early plant layout. In the present paper (Part 2), an index for evaluation of the hazard related to the potential of domino effects is developed. The index considers the actual consequences of possible escalation scenarios and scores or ranks the subsequent accident propagation potential. The effects of inherent and passive protection measures are also assessed. The result is a rapid quantification of domino hazard potential that can provide substantial support for choices in the early stages of layout design. Additionally, a case study concerning selection among various layout options is presented and analyzed. The case study demonstrates the use and applicability of the indices developed in both parts of the current work and highlights the value of introducing inherent safety features early in layout design.

  7. Reflecting Contemporary Design Research

    DEFF Research Database (Denmark)

    Engholm, Ida

    2017-01-01

    In recent years, design research has been the object of growing attention in universities and academies throughout the world. The present paper addresses the heterogeneous character of design research and the current need for reflection on the various approaches and interests. For this purpose......, the paper follows two steps. First, it proposes a categorization of the field in the form of a position model. The paper’s underlying assumption is that design research as a discipline exists in many different forms that cannot necessarily be brought together under one common academic research tradition......; instead it is necessary to attempt to define the field in order to initiate discussions about what constitutes the various research bases for design. Second, the paper discusses the implication for future design research when it is an interdisciplinary field that involves many disciplines, mindsets...

  8. Analytic Reflected Lightcurves for Exoplanets

    Science.gov (United States)

    Haggard, Hal M.; Cowan, Nicolas B.

    2018-04-01

    The disk-integrated reflected brightness of an exoplanet changes as a function of time due to orbital and rotational motion coupled with an inhomogeneous albedo map. We have previously derived analytic reflected lightcurves for spherical harmonic albedo maps in the special case of a synchronously-rotating planet on an edge-on orbit (Cowan, Fuentes & Haggard 2013). In this letter, we present analytic reflected lightcurves for the general case of a planet on an inclined orbit, with arbitrary spin period and non-zero obliquity. We do so for two different albedo basis maps: bright points (δ-maps), and spherical harmonics (Y_l^m-maps). In particular, we use Wigner D-matrices to express an harmonic lightcurve for an arbitrary viewing geometry as a non-linear combination of harmonic lightcurves for the simpler edge-on, synchronously rotating geometry. These solutions will enable future exploration of the degeneracies and information content of reflected lightcurves, as well as fast calculation of lightcurves for mapping exoplanets based on time-resolved photometry. To these ends we make available Exoplanet Analytic Reflected Lightcurves (EARL), a simple open-source code that allows rapid computation of reflected lightcurves.

  9. Dissociable Changes of Frontal and Parietal Cortices in Inherent Functional Flexibility across the Human Life Span.

    Science.gov (United States)

    Yin, Dazhi; Liu, Wenjing; Zeljic, Kristina; Wang, Zhiwei; Lv, Qian; Fan, Mingxia; Cheng, Wenhong; Wang, Zheng

    2016-09-28

    Extensive evidence suggests that frontoparietal regions can dynamically update their pattern of functional connectivity, supporting cognitive control and adaptive implementation of task demands. However, it is largely unknown whether this flexibly functional reconfiguration is intrinsic and occurs even in the absence of overt tasks. Based on recent advances in dynamics of resting-state functional resonance imaging (fMRI), we propose a probabilistic framework in which dynamic reconfiguration of intrinsic functional connectivity between each brain region and others can be represented as a probability distribution. A complexity measurement (i.e., entropy) was used to quantify functional flexibility, which characterizes heterogeneous connectivity between a particular region and others over time. Following this framework, we identified both functionally flexible and specialized regions over the human life span (112 healthy subjects from 13 to 76 years old). Across brainwide regions, we found regions showing high flexibility mainly in the higher-order association cortex, such as the lateral prefrontal cortex (LPFC), lateral parietal cortex, and lateral temporal lobules. In contrast, visual, auditory, and sensory areas exhibited low flexibility. Furthermore, we observed that flexibility of the right LPFC improved during maturation and reduced due to normal aging, with the opposite occurring for the left lateral parietal cortex. Our findings reveal dissociable changes of frontal and parietal cortices over the life span in terms of inherent functional flexibility. This study not only provides a new framework to quantify the spatiotemporal behavior of spontaneous brain activity, but also sheds light on the organizational principle behind changes in brain function across the human life span. Recent neuroscientific research has demonstrated that the human capability of adaptive task control is primarily the result of the flexible operation of frontal brain networks. However

  10. No inherent left and right side in human 'mental number line': evidence from right brain damage.

    Science.gov (United States)

    Aiello, Marilena; Jacquin-Courtois, Sophie; Merola, Sheila; Ottaviani, Teresa; Tomaiuolo, Francesco; Bueti, Domenica; Rossetti, Yves; Doricchi, Fabrizio

    2012-08-01

    Spatial reasoning has a relevant role in mathematics and helps daily computational activities. It is widely assumed that in cultures with left-to-right reading, numbers are organized along the mental equivalent of a ruler, the mental number line, with small magnitudes located to the left of larger ones. Patients with right brain damage can disregard smaller numbers while mentally setting the midpoint of number intervals. This has been interpreted as a sign of spatial neglect for numbers on the left side of the mental number line and taken as a strong argument for the intrinsic left-to-right organization of the mental number line. Here, we put forward the understanding of this cognitive disability by discovering that patients with right brain damage disregard smaller numbers both when these are mapped on the left side of the mental number line and on the right side of an imagined clock face. This shows that the right hemisphere supports the representation of small numerical magnitudes independently from their mapping on the left or the right side of a spatial-mental layout. In addition, the study of the anatomical correlates through voxel-based lesion-symptom mapping and the mapping of lesion peaks on the diffusion tensor imaging-based reconstruction of white matter pathways showed that the rightward bias in the imagined clock-face was correlated with lesions of high-level middle temporal visual areas that code stimuli in object-centred spatial coordinates, i.e. stimuli that, like a clock face, have an inherent left and right side. In contrast, bias towards higher numbers on the mental number line was linked to white matter damage in the frontal component of the parietal-frontal number network. These anatomical findings show that the human brain does not represent the mental number line as an object with an inherent left and right side. We conclude that the bias towards higher numbers in the mental bisection of number intervals does not depend on left side spatial

  11. Mapping Satellite Inherent Optical Properties Index in Coastal Waters of the Yucatán Peninsula (Mexico

    Directory of Open Access Journals (Sweden)

    Jesús A. Aguilar-Maldonado

    2018-06-01

    Full Text Available The Yucatán Peninsula hosts worldwide-known tourism destinations that concentrate most of the Mexico tourism activity. In this region, tourism has exponentially increased over the last years, including wildlife oriented tourism. Rapid tourism development, involving the consequent construction of hotels and tourist commodities, is associated with domestic sewage discharges from septic tanks. In this karstic environment, submarine groundwater discharges are very important and highly vulnerable to anthropogenic pollution. Nutrient loadings are linked to harmful algal blooms, which are an issue of concern to local and federal authorities due to their recurrence and socioeconomic and human health costs. In this study, we used satellite products from MODIS (Moderate Resolution Imaging Spectroradiometer to calculate and map the satellite Inherent Optical Properties (IOP Index. We worked with different scenarios considering both holiday and hydrological seasons. Our results showed that the satellite IOP Index allows one to build baseline information in a sustainable mid-term or long-term basis which is key for ecosystem-based management.

  12. Geriatric Respondents and Non-Respondents To Probiotic Intervention Can Be Differentiated By Inherent Gut Microbiome Composition

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    Suja eSenan

    2015-09-01

    Full Text Available Scope: Probiotic interventions are known to have been shown to influence the composition of the intestinal microbiota in geriatrics. The growing concern is the apparent variation in response to identical strain dosage among human volunteers. One factor that governs this variation is the host gut microbiome. In this study, we attempted to define a core gut metagenome which could act as a predisposition signature marker of inherent bacterial community that can help predict the success of a probiotic intervention. Methods and Results: To characterize the geriatric gut microbiome we designed primers targeting the 16S rRNA hypervariable region V2-V3 followed by semiconductor sequencing using Ion Torrent PGM. Among respondents and non- respondents the chief genera of phylum Firmicutes that showed significant differences are Lactobacillus, Clostridium, Eubacterium, and Blautia (q< 0.002 while in the genera of phylum Proteobacteria included Shigella, Escherichia, Burkholderia and Camphylobacter (q <0.002. Conclusion: We have identified potential microbial biomarkers and taxonomic patterns that correlate with a positive response to probiotic intervention in geriatric volunteers. Future work with larger cohorts of geriatrics with diverse dietary influences could reveal the potential of the signature patterns of microbiota for personalized nutrition.

  13. Simple frequency-dependent tools for analysis of inherent control limitations

    Directory of Open Access Journals (Sweden)

    Sigurd Skogestad

    1991-10-01

    Full Text Available By a plant's inherent control limitations we mean the characteristics of the plant which will cause poor control performance irrespective of what controller is used. Another frequently used term is 'dynamic resilience' which is the best closed-loop performance achievable using any controller. Since a plant's dynamic resilience cannot be altered by change of the control algorithm, but only by design modifications, it follows that the term controllability provides a link between process design and process control. In this paper we focus on two aspects of controllability. The plants' sensitivity to disturbances and the limitations imposed by interactions when using decentralized control. We use simple tools such as the RGA, the PRGA (Performance RGA and the closely related Closed Loop Disturbance Gain (CLDG. For example, if kth column of the CLDG is large, then this indicates that disturbance k will be difficult to reject. This may pinpoint the need for modifying the process. The PRGA provides a measure of interaction which also includes one-way coupling. In the paper we apply these measures to distillation column control and fluid catalytic cracker (FCC control.

  14. A Mechanistic Reliability Assessment of RVACS and Metal Fuel Inherent Reactivity Feedbacks

    Energy Technology Data Exchange (ETDEWEB)

    Grabaskas, David; Brunett, Acacia J.; Passerini, Stefano; Grelle, Austin

    2017-09-24

    GE Hitachi Nuclear Energy (GEH) and Argonne National Laboratory (Argonne) participated in a two year collaboration to modernize and update the probabilistic risk assessment (PRA) for the PRISM sodium fast reactor. At a high level, the primary outcome of the project was the development of a next-generation PRA that is intended to enable risk-informed prioritization of safety- and reliability-focused research and development. A central Argonne task during this project was a reliability assessment of passive safety systems, which included the Reactor Vessel Auxiliary Cooling System (RVACS) and the inherent reactivity feedbacks of the metal fuel core. Both systems were examined utilizing a methodology derived from the Reliability Method for Passive Safety Functions (RMPS), with an emphasis on developing success criteria based on mechanistic system modeling while also maintaining consistency with the Fuel Damage Categories (FDCs) of the mechanistic source term assessment. This paper provides an overview of the reliability analyses of both systems, including highlights of the FMEAs, the construction of best-estimate models, uncertain parameter screening and propagation, and the quantification of system failure probability. In particular, special focus is given to the methodologies to perform the analysis of uncertainty propagation and the determination of the likelihood of violating FDC limits. Additionally, important lessons learned are also reviewed, such as optimal sampling methodologies for the discovery of low likelihood failure events and strategies for the combined treatment of aleatory and epistemic uncertainties.

  15. Bayesian estimation inherent in a Mexican-hat-type neural network

    Science.gov (United States)

    Takiyama, Ken

    2016-05-01

    Brain functions, such as perception, motor control and learning, and decision making, have been explained based on a Bayesian framework, i.e., to decrease the effects of noise inherent in the human nervous system or external environment, our brain integrates sensory and a priori information in a Bayesian optimal manner. However, it remains unclear how Bayesian computations are implemented in the brain. Herein, I address this issue by analyzing a Mexican-hat-type neural network, which was used as a model of the visual cortex, motor cortex, and prefrontal cortex. I analytically demonstrate that the dynamics of an order parameter in the model corresponds exactly to a variational inference of a linear Gaussian state-space model, a Bayesian estimation, when the strength of recurrent synaptic connectivity is appropriately stronger than that of an external stimulus, a plausible condition in the brain. This exact correspondence can reveal the relationship between the parameters in the Bayesian estimation and those in the neural network, providing insight for understanding brain functions.

  16. Circumvention of inherent or acquired cytotoxic drug resistance in vitro using combinations of modulating agents.

    Science.gov (United States)

    Cadagan, David; Merry, Stephen

    2013-10-01

    Modulating agents are used to circumvent drug resistance in the clinical setting. However achievable serum concentrations are often lower than those which are optimal in vitro. Combination of modulating agents with non-overlapping toxicities may overcome this obstacle. We have investigated combinations of three modulating agents (quinine, verapamil, and cinnarizine) to circumvent inherent or acquired resistance to the cytotoxic drugs doxorubicin, vincristine and paclitaxel. Dose-response curves to cytotoxic drugs in the presence/absence of modulating agents were determined using colony formation and cell proliferation assays. Doxorubicin accumulation into cell monolayers was measured by fluorescence spectrophotometry. Greater (1.9-fold) sensitisation to particular cytotoxic drugs was observed for certain combinations of modulating agents compared to individual effects. The most effective combination was quinine-plus-verapamil with the cytotoxic drug doxorubicin. This increase in sensitivity was associated with increased doxorubicin accumulation. Such enhanced activity was, however, not observed for all combinations of modulating agents or for all studied cytotoxic drugs. The findings of the present study suggest certain combinations of modulating agents to have a clinical role in circumventing drug resistance. Particular combinations of modulating agents must be carefully chosen to suit particular cytotoxic drug treatments.

  17. Bionic Ears: Their Development and Future Advances Using Neurotrophins and Inherently Conducting Polymers

    Directory of Open Access Journals (Sweden)

    Graeme M. Clark

    2004-01-01

    Full Text Available The development of the multiple-channel bionic ear for hearing and speech understanding in profoundly deaf people is the result of integrating biological and physical sciences with engineering. It is the first clinically successful restoration of sensory and brain function, and brings electronic technology into a direct functional relationship with human consciousness. It presently transmits essential place and coarse temporal information for the coding of frequency, but the fine temporal and place excitation of groups of nerve fibres is inadequate for high-fidelity sound. This is required for adequate musical appreciation and hearing in noise. Research has demonstrated that nerve growth factors preserve the peripheral processes of the auditory nerves so that an electrode array placed close to these fibres could produce this fine temporal and spatial coding. The nerve growth factors can be incorporated into inherently conducting polymers that are part of the array so the peripheral processes can be preserved at the same time as they are electrically stimulated.

  18. Retrieving Marine Inherent Optical Properties from Satellites Using Temperature and Salinity-dependent Backscattering by Seawater

    Science.gov (United States)

    Werdell, Paul J.; Franz, Bryan Alden; Lefler, Jason Travis; Robinson, Wayne D.; Boss, Emmanuel

    2013-01-01

    Time-series of marine inherent optical properties (IOPs) from ocean color satellite instruments provide valuable data records for studying long-term time changes in ocean ecosystems. Semi-analytical algorithms (SAAs) provide a common method for estimating IOPs from radiometric measurements of the marine light field. Most SAAs assign constant spectral values for seawater absorption and backscattering, assume spectral shape functions of the remaining constituent absorption and scattering components (e.g., phytoplankton, non-algal particles, and colored dissolved organic matter), and retrieve the magnitudes of each remaining constituent required to match the spectral distribution of measured radiances. Here, we explore the use of temperature- and salinity-dependent values for seawater backscattering in lieu of the constant spectrum currently employed by most SAAs. Our results suggest that use of temperature- and salinity-dependent seawater spectra elevate the SAA-derived particle backscattering, reduce the non-algal particles plus colored dissolved organic matter absorption, and leave the derived absorption by phytoplankton unchanged.

  19. Conservatism inherent to simplified qualification techniques used for piping steady state vibration

    International Nuclear Information System (INIS)

    Olson, D.E.; Smetters, J.L.

    1983-01-01

    This paper examines some of the qualification techniques currently used by the power industry, including the techniques specified in a recently issued standard related to this subject (ANSI/ASME OM-3, Requirements for Preoperational and Initial Startup Vibration Testing of Nuclear Power Plant Piping Systems). Several methods are used to demonstrate the amount of conservatism inherent in these techniques. Allowable limits calculated by the use of simplified techniques are compared to limits calculated by more detailed computer analysis. A portion of a reactor feedwater piping system along with the results of a piping vibration monitoring program recently completed in a nuclear power plant are used as case studies. The limits determined by the use of simplified criteria are also compared to limits determined empirically through the use of strain gauges. The simple beam analogies that use vibrational displacement as acceptance criteria were found to be conservative for all the examples studied. However, when velocity was used as a criterion, it was not always conservative. Simplified techniques that result in displacement allowables appear to be the most viable method of qualifying piping vibrations. Quantities referred to in the paper are cited in British units throughout. These may be converted to the International System of Units (SI) as follows: 1 foot=0.3048 meter; 1 inch=0.0254 meter=1,000 mils; 1 psi=6,894 pascals; and 1 inch/second=0.0254 meter/second. (orig.)

  20. Preliminary risk assessment of the Integral Inherently-Safe Light Water Reactor

    International Nuclear Information System (INIS)

    McCarroll, Kellen R.; Lee, John C.; Manera, Annalisa; Memmott, Matthew J.; Ferroni, Paolo

    2017-01-01

    The Integral, Inherently Safe Light Water Reactor (I 2 S-LWR) concept seeks to significantly increase nuclear power plant safety. The project implements a safety-by-design philosophy, eliminating several initiating events and providing novel, passive safety systems at the conceptual phase. Pursuit of unparalleled safety employs an integrated development process linking design with deterministic and probabilistic safety analyses. Unique aspects of the I 2 S-LWR concept and design process present challenges to the probabilistic risk assessment (PRA), particularly regarding overall flexibility, auditability and resolution of results. Useful approaches to initiating events and conditional failures are presented. To exemplify the risk-informed design process using PRA, a trade-off study of two safety system configurations is presented. Although further optimization is required, preliminary results indicate that the I 2 S-LWR can achieve a core damage frequency (CDF) from internal events less than 1.01 × 10 −8 /ry, including reactor vessel ruptures. Containment bypass frequency due to primary heat exchanger rupture is found to be comparable to non-vessel rupture CDF.