WorldWideScience

Sample records for reducing manufacturing costs

  1. Lean Manufacturing Implementation: an Approach to Reduce Production Cost

    Directory of Open Access Journals (Sweden)

    Iraswari

    2012-04-01

    Full Text Available Abstract: Lean Manufacturing Implementation: An Approach To Reduce Production Cost. Opportunities to improve production processes and reduce production cost through the implementation of lean manufacturing in small medium garment manufacturing are presented in this research. This research shows that there is a possibility of decrease in production cost and increase in return on sales. Lean manufacturing implementation can eliminate waste in the production process. This is a set of techniques for identification and elimination of waste gathered from The Ford Production, Statistical Process Control and other techniques. Improvement of quality could be carried out while time and cost of production are being reduced.

  2. Operating Costs Reducing in MDF Manufacturing Industries

    Directory of Open Access Journals (Sweden)

    José Augusto Coeve Florino

    2014-05-01

    Full Text Available The sustained efforts by electric motors when subjected to cutting, trimming or finishing are directly related to the material being machined and the angle of attack of the tool. Choosing the right tool for this operation depends on an expected result. So the engines behave differently to each operation. The optimization between strength, speed, power, material and type of operation, can be found to reduce operational costs of production, besides determining the exact time to make the set-up of worn tool. The reduction in operating costs is an item of sustainability that outlines the strategic positioning on companies to become competitive in the global marketplace. With the great technological development present today, this issue goes away with the very latest products on the market for professionals who productivity will be dealt with in these modern maintenance equipment such as power quality analyzer, Imager, profile projector and microscope for research. The result of this work is the optimization of the cutting operation and energy consumption thereby demonstrating an optimum point of operation in a case study presented in this work.

  3. Multiple oligo nucleotide arrays: Methods to reduce manufacture time and cost

    CERN Document Server

    Ning, Kang

    2010-01-01

    The customized multiple arrays are becoming vastly used in microarray experiments for varies purposes, mainly for its ability to handle a large quantity of data and output high quality results. However, experimenters who use customized multiple arrays still face many problems, such as the cost and time to manufacture the masks, and the cost for production of the multiple arrays by costly machines. Although there is some research on the multiple arrays, there is little concern on the manufacture time and cost, which is actually important to experimenters. In this paper, we have proposed methods to reduce the time and cost for the manufacture of the customized multiple arrays. We have first introduced a heuristic algorithm for the mask decomposition problem for multiple arrays. Then a streamline method is proposed for the integration of different steps of manufacture on a higher level. Experiments show that our methods are very effective in reduction of the time and cost of manufacture of multiple arrays.

  4. Utilization of UV Curing Technology to Significantly Reduce the Manufacturing Cost of LIB Electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Voelker, Gary [Miltec UV International, LLC, Stevensville, MD (United States); Arnold, John [Miltec UV International, LLC, Stevensville, MD (United States)

    2015-11-30

    Previously identified novel binders and associated UV curing technology have been shown to reduce the time required to apply and finish electrode coatings from tens of minutes to less than one second. This revolutionary approach can result in dramatic increases in process speeds, significantly reduced capital (a factor of 10 to 20) and operating costs, reduced energy requirements, and reduced environmental concerns and costs due to the virtual elimination of harmful volatile organic solvents and associated solvent dryers and recovery systems. The accumulated advantages of higher speed, lower capital and operating costs, reduced footprint, lack of VOC recovery, and reduced energy cost is a reduction of 90% in the manufacturing cost of cathodes. When commercialized, the resulting cost reduction in Lithium batteries will allow storage device manufacturers to expand their sales in the market and thereby accrue the energy savings of broader utilization of HEVs, PHEVs and EVs in the U.S., and a broad technology export market is also envisioned.

  5. Reduced Multivariate Polynomial Model for Manufacturing Costs Estimation of Piping Elements

    Directory of Open Access Journals (Sweden)

    Nibaldo Rodriguez

    2013-01-01

    Full Text Available This paper discusses the development and evaluation of an estimation model of manufacturing costs of piping elements through the application of a Reduced Multivariate Polynomial (RMP. The model allows obtaining accurate estimations, even when enough and adequate information is not available. This situation typically occurs in the early stages of the design process of industrial products. The experimental evaluations show that the approach is capable, with a low complexity, of reducing uncertainties and to predict costs with significant precision. Comparisons with a neural network showed also that the RMP performs better considering a set of classical performance measures with the corresponding lower complexity and higher accuracy.

  6. Technology Needs for Reduced Design and Manufacturing Cost of Commercial Transport Engines

    Science.gov (United States)

    Rohn, Douglas A.

    1997-01-01

    The objective of the study was to assess the needs in the design and manufacturing processes and identify areas where technology could impact in cost and cycle-time reduction. At the highest level, the team first identified the goals that were in line with long-range needs of the aeropropulsion industry, and to which technology and process improvements would be required to contribute. These goals are to reduce the time and costs in the development cycle of aircraft engines by a factor of two, reduce production cycle time by a factor of four, and to reduce production costs by 25%. Also, it was the intent of the team to identify the highest impact technologies that could be developed and demonstrated in five years.

  7. Reducing metal alloy powder costs for use in powder bed fusion additive manufacturing: Improving the economics for production

    Science.gov (United States)

    Medina, Fransisco

    Titanium and its associated alloys have been used in industry for over 50 years and have become more popular in the recent decades. Titanium has been most successful in areas where the high strength to weight ratio provides an advantage over aluminum and steels. Other advantages of titanium include biocompatibility and corrosion resistance. Electron Beam Melting (EBM) is an additive manufacturing (AM) technology that has been successfully applied in the manufacturing of titanium components for the aerospace and medical industry with equivalent or better mechanical properties as parts fabricated via more traditional casting and machining methods. As the demand for titanium powder continues to increase, the price also increases. Titanium spheroidized powder from different vendors has a price range from 260/kg-450/kg, other spheroidized alloys such as Niobium can cost as high as $1,200/kg. Alternative titanium powders produced from methods such as the Titanium Hydride-Dehydride (HDH) process and the Armstrong Commercially Pure Titanium (CPTi) process can be fabricated at a fraction of the cost of powders fabricated via gas atomization. The alternative powders can be spheroidized and blended. Current sectors in additive manufacturing such as the medical industry are concerned that there will not be enough spherical powder for production and are seeking other powder options. It is believed the EBM technology can use a blend of spherical and angular powder to build fully dense parts with equal mechanical properties to those produced using traditional powders. Some of the challenges with angular and irregular powders are overcoming the poor flow characteristics and the attainment of the same or better packing densities as spherical powders. The goal of this research is to demonstrate the feasibility of utilizing alternative and lower cost powders in the EBM process. As a result, reducing the cost of the raw material to reduce the overall cost of the product produced with

  8. Cost analysis methodology: Photovoltaic Manufacturing Technology Project

    Energy Technology Data Exchange (ETDEWEB)

    Whisnant, R.A. (Research Triangle Inst., Research Triangle Park, NC (United States))

    1992-09-01

    This report describes work done under Phase 1 of the Photovoltaic Manufacturing Technology (PVMaT) Project. PVMaT is a five-year project to support the translation of research and development in PV technology into the marketplace. PVMaT, conceived as a DOE/industry partnership, seeks to advanced PV manufacturing technologies, reduce PV module production costs, increase module performance, and expand US commercial production capacities. Under PVMaT, manufacturers will propose specific manufacturing process improvements that may contribute to the goals of the project, which is to lessen the cost, thus hastening entry into the larger scale, grid-connected applications. Phase 1 of the PVMaT project is to identify obstacles and problems associated with manufacturing processes. This report describes the cost analysis methodology required under Phase 1 that will allow subcontractors to be ranked and evaluated during Phase 2.

  9. Cost Management of Motor Manufacturing Industry

    Institute of Scientific and Technical Information of China (English)

    Liu Chunyan

    2013-01-01

    Through the study on the way to reduce the cost of motor manufacturing industry, this paper ful y infiltrates the definition of cost into al aspects of enterprise production and operation. That is to say, only comprehensive, ful-staf and ful-proces cost control can greatly enhance enterprise competitivenes initiative at the time of enhancing the competitiveness of enterprise products in the market.

  10. Dairy Product Manufacturing Costs at Cooperative Plants

    OpenAIRE

    Ling, K. Charles

    1983-01-01

    Cost data are summarized for 14 plants manufacturing cheese, butter, and powder and average costs are presented for each product. Average cost curves are estimated for each plant. The scale of plant for least-cost operations is identified for plants of each product type. Plant capacity utilization and seasonal volume variation and their impacts on manufacturing cost are delineated.

  11. Further Cost Reduction of Battery Manufacturing

    Directory of Open Access Journals (Sweden)

    Amir A. Asif

    2017-06-01

    Full Text Available The demand for batteries for energy storage is growing with the rapid increase in photovoltaics (PV and wind energy installation as well as electric vehicle (EV, hybrid electric vehicle (HEV and plug-in hybrid electric vehicle (PHEV. Electrochemical batteries have emerged as the preferred choice for most of the consumer product applications. Cost reduction of batteries will accelerate the growth in all of these sectors. Lithium-ion (Li-ion and solid-state batteries are showing promise through their downward price and upward performance trends. We may achieve further performance improvement and cost reduction for Li-ion and solid-state batteries through reduction of the variation in physical and electrical properties. These properties can be improved and made uniform by considering the electrical model of batteries and adopting novel manufacturing approaches. Using quantum-photo effect, the incorporation of ultra-violet (UV assisted photo-thermal processing can reduce metal surface roughness. Using in-situ measurements, advanced process control (APC can help ensure uniformity among the constituent electrochemical cells. Industrial internet of things (IIoT can streamline the production flow. In this article, we have examined the issue of electrochemical battery manufacturing of Li-ion and solid-state type from cell-level to battery-level process variability, and proposed potential areas where improvements in the manufacturing process can be made. By incorporating these practices in the manufacturing process we expect reduced cost of energy management system, improved reliability and yield gain with the net saving of manufacturing cost being at least 20%.

  12. Advanced manufacturing technologies for reduced cost and weight in portable ruggedized VIS-IR and multi-mode optical systems for land, sea, and air

    Science.gov (United States)

    Sweeney, Michael; Spinazzola, Robert; Morrison, Donald; Macklin, Dennis; Marion, Jared

    2011-06-01

    Homeland security systems, special forces, unmanned aerial vehicles (UAV), and marine patrols require low cost, high performance, multi-mode visible through infrared (VIS-IR) wavelength optical systems to identify and neutralize potential threats that often arise at long ranges and under poor visibility conditions. Long range and wide spectral performance requirements favor reflective optical system design solutions. The limited field of view of such designs can be significantly enhanced by the use of catadioptric optical solutions that utilize molded or diamond point machined VIS-IR lenses downstream from reflective objective optics. A common optical aperture that services multiple modes of field-of-view, operating wavelength, and includes laser ranging and spotting, provides the highest utility and is most ideal for size and weight. Such a design also often requires fast, highly aspheric, reflective, refractive, and sometimes diffractive surfaces using high performance and aggressively light-weighted materials that demand the finest of manufacturing technologies. Visible wavelength performance sets the bar for component optical surface irregularity on the order of 20 nm RMS and surface finishes less than 3.0 nm RMS. Aluminum mirrors and structures can also be precision machined to yield "snap together alignment" or limited compensation assembly approaches to reduce cost and enhance interchangeability. Diamond point turning, die cast and investment cast mirror substrates and structures, computerized optical polishing, mirror replication, lens molding and other advanced manufacturing technologies can all be used to minimize the cost of this type of optical equipment. This paper discusses the tradeoffs among materials and process selection for catadioptric, multi-mode systems that are under development for a variety of DoD and Homeland Security applications. Several examples are profiled to illuminate the confluence of applicable design and manufacturing

  13. Low Cost Method of Manufacturing Space Optics Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Phase I project successfully demonstrated the feasibility of developing a technology that will reduce cost and manufacturing time, broaden design options, and...

  14. An analysis of glass–glass CIGS manufacturing costs

    Energy Technology Data Exchange (ETDEWEB)

    Horowitz, Kelsey A. W.; Fu, Ran; Woodhouse, Michael

    2016-09-01

    This article examines current cost drivers and potential avenues to reduced cost for monolithic, glass-glass Cu(In,Ga)(Se,S)2 (CIGS) modules by constructing a comprehensive bottom-up cost model. For a reference case where sputtering plus batch sulfurization after selenization (SAS) is employed, we compute a manufacturing cost of $69/m2 if the modules are made in the United States at a 1 GW/year production volume. At 14% module efficiency, this corresponds to a manufacturing cost of $0.49/WDC and a minimum sustainable price (MSP) of $0.67/WDC. We estimate that MSP could vary within +/-20% of this value given the range of quoted input prices, and existing variations in module design, manufacturing processes, and manufacturing location. Potential for reduction in manufacturing costs to below $0.40/WDC may be possible if average production module efficiencies can be increased above 17% without increasing $/m2 costs; even lower costs could be achieved if $/m2 costs could be reduced, particularly via innovations in the CIGS deposition process or balance-of-module elements. We present the impact on cost of regional factors, CIGS deposition method, device design, and price fluctuations. One metric of competitiveness-levelized cost of energy (LCOE) -- is also assessed for several U.S. locations and compared to that of standard multi-crystalline silicon (m(c-Si)) and cadmium telluride (CdTe).

  15. Low Cost Lithography Tool for High Brightness LED Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Andrew Hawryluk; Emily True

    2012-06-30

    The objective of this activity was to address the need for improved manufacturing tools for LEDs. Improvements include lower cost (both capital equipment cost reductions and cost-ofownership reductions), better automation and better yields. To meet the DOE objective of $1- 2/kilolumen, it will be necessary to develop these highly automated manufacturing tools. Lithography is used extensively in the fabrication of high-brightness LEDs, but the tools used to date are not scalable to high-volume manufacturing. This activity addressed the LED lithography process. During R&D and low volume manufacturing, most LED companies use contact-printers. However, several industries have shown that these printers are incompatible with high volume manufacturing and the LED industry needs to evolve to projection steppers. The need for projection lithography tools for LED manufacturing is identified in the Solid State Lighting Manufacturing Roadmap Draft, June 2009. The Roadmap states that Projection tools are needed by 2011. This work will modify a stepper, originally designed for semiconductor manufacturing, for use in LED manufacturing. This work addresses improvements to yield, material handling, automation and throughput for LED manufacturing while reducing the capital equipment cost.

  16. Manufacturing cost analysis of integrated photonic packages

    Science.gov (United States)

    Stirk, Charles W.; Liu, Qin; Ball, Matthew V.

    1999-04-01

    This paper analyzes the manufacturing cost of photonic system using software that combines several methods for accurate cost accounting. Activity based costing assigns al capital equipment, material and labor costs directly to the product rather than to overheads. Cost of ownership models determine the cost of using machines under different financial and utilization scenarios. Libraries of standard machines, process steps, and process sequences facilitate rapid model building and modification. Using libraries for semiconductor and photonics fabrication, along with packaging and optomechanical assembly, we construct cost models for 2D VCSEL array communication modules. The result of the analysis is that the model cost is driven mainly by the epitaxial material cost, and laser yield limits VCSEL arrays to small scale integration.

  17. Developing Cost Effective Automation In Soap Manufacturing

    Directory of Open Access Journals (Sweden)

    Rajesh B. Salwe

    2014-01-01

    Full Text Available A low cost automation system for soap manufacturing is to be designed and developed. The setup consists of mixer in which the raw material is mixed for the process of soap making. The mixture is then carried into a tray to a stamping machine. The plunger embosses on raw material of soap to give desired shape and size to the soap in a low cost manner.

  18. Developing Cost Effective Automation In Soap Manufacturing

    OpenAIRE

    Rajesh B. Salwe; Prof.S.V.Dahake

    2014-01-01

    A low cost automation system for soap manufacturing is to be designed and developed. The setup consists of mixer in which the raw material is mixed for the process of soap making. The mixture is then carried into a tray to a stamping machine. The plunger embosses on raw material of soap to give desired shape and size to the soap in a low cost manner.

  19. Cost Models for MMC Manufacturing Processes

    Science.gov (United States)

    Elzey, Dana M.; Wadley, Haydn N. G.

    1996-01-01

    Processes for the manufacture of advanced metal matrix composites are rapidly approaching maturity in the research laboratory and there is growing interest in their transition to industrial production. However, research conducted to date has almost exclusively focused on overcoming the technical barriers to producing high-quality material and little attention has been given to the economical feasibility of these laboratory approaches and process cost issues. A quantitative cost modeling (QCM) approach was developed to address these issues. QCM are cost analysis tools based on predictive process models relating process conditions to the attributes of the final product. An important attribute, of the QCM approach is the ability to predict the sensitivity of material production costs to product quality and to quantitatively explore trade-offs between cost and quality. Applications of the cost models allow more efficient direction of future MMC process technology development and a more accurate assessment of MMC market potential. Cost models were developed for two state-of-the art metal matrix composite (MMC) manufacturing processes: tape casting and plasma spray deposition. Quality and Cost models are presented for both processes and the resulting predicted quality-cost curves are presented and discussed.

  20. Costs Analysis of Iron Casts Manufacturing

    Directory of Open Access Journals (Sweden)

    S. Kukla

    2012-04-01

    Full Text Available The article presents the issues of costs analysis of iron casts manufacturing using automated foundry lines. Particular attention was paid to departmental costs, conversion costs and costs of in-plant transport. After the Pareto analysis had been carried out, it was possible to set the model area of the process and focus on improving activities related to finishing of a chosen group of casts. In order to eliminate losses, the activities realised in this domain were divided into activities with added value, activities with partially added value and activities without added value. To streamline the production flow, it was proposed to change the location of workstations related to grinding, control and machining of casts. Within the process of constant improvement of manufacturing processes, the aspect of work ergonomics at a workstation was taken into account. As a result of the undertaken actions, some activities without added value were eliminated, efficiency was increased and prime costs of manufacturing casts with regard to finishing treatment were lowered.

  1. Metaldyne. Plant-Wide Assessment at Royal Oak Finds Opportunities to Improve Manufacturing Effciency, Reduce Energy Use, and Achieve Sigificant Cost Savings

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2005-05-01

    This case study prepared for the U.S. Department of Energy's Industrial Technologies Program describes a plant-wide energy assessment conducted at the Metaldyne, Inc., forging plant in Royal Oak, Michigan. The assessment focused on reducing the plant's operating costs, inventory, and energy use. If the company were to implement all the recommendations that came out of the assessment, its total annual energy savings for electricity would be about 11.5 million kWh and annual cost savings would be $12.6 million.

  2. Reducing Lifecycle Sustainment Costs

    Science.gov (United States)

    2015-05-01

    funding is not allocated for its implementation .  Technology Refresh often requires non-recurring engineering investment, but the Working Capital Funds...Enterprise Resource Planning ( ERP ) systems • Industry • Government • Keys to Achieving O&S Cost Reduction Agenda 6 O&S Cost Estimating...policy and conducts oversight – Military departments are allowed considerable latitude in implementation • Army: OSMIS • Navy: Navy VAMOSC • Air

  3. Additive Manufacturing of Low Cost Upper Stage Propulsion Components

    Science.gov (United States)

    Protz, Christopher; Bowman, Randy; Cooper, Ken; Fikes, John; Taminger, Karen; Wright, Belinda

    2014-01-01

    NASA is currently developing Additive Manufacturing (AM) technologies and design tools aimed at reducing the costs and manufacturing time of regeneratively cooled rocket engine components. These Low Cost Upper Stage Propulsion (LCUSP) tasks are funded through NASA's Game Changing Development Program in the Space Technology Mission Directorate. The LCUSP project will develop a copper alloy additive manufacturing design process and develop and optimize the Electron Beam Freeform Fabrication (EBF3) manufacturing process to direct deposit a nickel alloy structural jacket and manifolds onto an SLM manufactured GRCop chamber and Ni-alloy nozzle. In order to develop these processes, the project will characterize both the microstructural and mechanical properties of the SLMproduced GRCop-84, and will explore and document novel design techniques specific to AM combustion devices components. These manufacturing technologies will be used to build a 25K-class regenerative chamber and nozzle (to be used with tested DMLS injectors) that will be tested individually and as a system in hot fire tests to demonstrate the applicability of the technologies. These tasks are expected to bring costs and manufacturing time down as spacecraft propulsion systems typically comprise more than 70% of the total vehicle cost and account for a significant portion of the development schedule. Additionally, high pressure/high temperature combustion chambers and nozzles must be regeneratively cooled to survive their operating environment, causing their design to be time consuming and costly to build. LCUSP presents an opportunity to develop and demonstrate a process that can infuse these technologies into industry, build competition, and drive down costs of future engines.

  4. Assessment of low-cost manufacturing process sequences. [photovoltaic solar arrays

    Science.gov (United States)

    Chamberlain, R. G.

    1979-01-01

    An extensive research and development activity to reduce the cost of manufacturing photovoltaic solar arrays by a factor of approximately one hundred is discussed. Proposed and actual manufacturing process descriptions were compared to manufacturing costs. An overview of this methodology is presented.

  5. Cost effective manufacturing of the SEA 10X concentrator array

    Energy Technology Data Exchange (ETDEWEB)

    Kaminar, N.; McEntee, J.; Curchod, D. (Solar Engineering Applications Corp., San Jose, CA (United States))

    1991-11-01

    This report describes a low-cost, mass-producible 10X concentrator system that has been claimed to produce electricity at $0.04/kWh. It details changes in manufacturing techniques that could produce a concentrator system at a selling price of $0.71/W. (A simple design and a minimum number of parts and manufacturing steps reduced production costs.) Present production techniques, changes to improve these techniques, impediments to changes, and solutions to the impediments are described. This 10X concentrator system uses available components and manufacturing processes and one-sun solar cells in conjunction with inexpensive plastic lenses to generate about eight times the amount of electricity normally produced by these cells.

  6. Cost, resources, and energy efficiency of additive manufacturing

    Directory of Open Access Journals (Sweden)

    Dudek Piotr

    2017-01-01

    Full Text Available Additive manufacturing (AM is the process of joining materials to make objects from Computer Aided Design (CAD model data, usually layer upon layer, as opposed to using subtractive manufacturing methods. The use of rapid prototyping technologies has increased significantly in recent years. These new techniques, while still evolving, are projected to exert a profound impact on manufacturing. They can reduce energy use and time to market and offer industry new design flexibility. We include a brief study on the cost and energy efficiency of selected methods of additive manufacturing compared to traditional methods of manufacturing parts. One common claim is that 3D printers are more energy-efficient than other manufacturing technologies. We present energy efficiency and time requirements for producing a typical mechanical part and a very complicated element, using both traditional manufacturing and rapid prototyping methods. This paper represents an attempt to answer the questions of when 3D printing can be used efficiently and of choosing the appropriate technology on the basis of batch size, element size, complexity, and material requirements.

  7. Low Cost Method of Manufacturing Space Optics Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Proposed is the development of a manufacturing technology that will increase feasible large optics design options and significantly reduce the manufacturing time,...

  8. Transportation cost minimization of a manufacturing firm using ...

    African Journals Online (AJOL)

    Transportation cost minimization of a manufacturing firm using genetic algorithm approach. ... Nigerian Journal of Technology ... the transportation cost) and a corresponding increase in its transportation cost as a result of government's removal ...

  9. SOLID OXIDE FUEL CELL MANUFACTURING COST MODEL: SIMULATING RELATIONSHIPS BETWEEN PERFORMANCE, MANUFACTURING, AND COST OF PRODUCTION

    Energy Technology Data Exchange (ETDEWEB)

    Eric J. Carlson; Yong Yang; Chandler Fulton

    2004-04-20

    The successful commercialization of fuel cells will depend on the achievement of competitive system costs and efficiencies. System cost directly impacts the capital equipment component of cost of electricity (COE) and is a major contributor to the O and M component. The replacement costs for equipment (also heavily influenced by stack life) is generally a major contributor to O and M costs. In this project, they worked with the SECA industrial teams to estimate the impact of general manufacturing issues of interest on stack cost using an activities-based cost model for anode-supported planar SOFC stacks with metallic interconnects. An earlier model developed for NETL for anode supported planar SOFCs was enhanced by a linkage to a performance/thermal/mechanical model, by addition of Quality Control steps to the process flow with specific characterization methods, and by assessment of economies of scale. The 3-dimensional adiabatic performance model was used to calculate the average power density for the assumed geometry and operating conditions (i.e., inlet and exhaust temperatures, utilization, and fuel composition) based on publicly available polarizations curves. The SECA team provided guidance on what manufacturing and design issues should be assessed in this Phase I demonstration of cost modeling capabilities. They considered the impact of the following parameters on yield and cost: layer thickness (i.e., anode, electrolyte, and cathode) on cost and stress levels, statistical nature of ceramic material failure on yield, and Quality Control steps and strategies. In this demonstration of the capabilities of the linked model, only the active stack (i.e., anode, electrolyte, and cathode) and interconnect materials were included in the analysis. Factory costs are presented on an area and kilowatt basis to allow developers to extrapolate to their level of performance, stack design, materials, seal and system configurations, and internal corporate overheads and margin

  10. Cost-benefit analysis for design of environmentally conscious manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Matysiak, L.M.

    1993-09-01

    In recent years, much attention has been focused on reducing the environmental impacts of products and manufacturing processes. Concerned about rising compliance costs and stringent regulatory requirements, companies are carefully evaluating the environmental impacts of their products. In response, designers, engineers, and managers are beginning to use life-cycle analysis, design for environment techniques, and environmentally conscious manufacturing (ECM) as tools to help them to not only do what is best for the environment, but also to do what is best for their company. These tools are also a useful aid in evaluating the trade-offs that may exist between different product and process alternatives. However, how does one choose the optimal solution from these various product and process alternatives? Cost versus benefit analysis is an effective tool that can be used to evaluate various manufacturing alternatives and to choose a solution that is both cost effective and environmentally compatible. Many companies are beginning to use cost benefit analyses as a means to justify product or process modifications that result in a benefit to the environment.

  11. Manufacturing cost/design system: A CAD/CAM dialogue

    Science.gov (United States)

    Loshigian, H. H.; Rachowitz, B. I.; Judson, D.

    1980-01-01

    The development of the Manufacturing Cost/Design System (MC/DS) will provide the aerospace design engineer a tool with which to perform heretofore impractical design manufacturing cost tradeoffs. The Air Force Integrated Computer Aided Manufacturing (ICAM) Office has initiated the development and demonstration of an MC/DS which, when fully implemented, will integrate both design and manufacturing data bases to provide real time visibility into the manufacturing costs associated with various design options. The first release of a computerized system will be made before the end of 1981.

  12. V1.6 Development of Advanced Manufacturing Technologies for Low Cost Hydrogen Storage Vessels

    Energy Technology Data Exchange (ETDEWEB)

    Leavitt, Mark; Lam, Patrick; Nelson, Karl M.; johnson, Brice A.; Johnson, Kenneth I.; Alvine, Kyle J.; Ruiz, Antonio; Adams, Jesse

    2012-10-01

    The goal of this project is to develop an innovative manufacturing process for Type IV high-pressure hydrogen storage vessels, with the intent to significantly lower manufacturing costs. Part of the development is to integrate the features of high precision AFP and commercial FW. Evaluation of an alternative fiber to replace a portion of the baseline fiber will help to reduce costs further.

  13. COST OF QUALITY MODELS AND THEIR IMPLEMENTATION IN MANUFACTURING FIRMS

    Directory of Open Access Journals (Sweden)

    N.M. Vaxevanidis

    2009-03-01

    Full Text Available In order to improve quality, an organization must take into account the costs associated with achieving quality since the objective of continuous improvement programs is not only to meet customer requirements, but also to do it at the lowest, possible, cost. This can only obtained by reducing the costs needed to achieve quality, and the reduction of these costs is only possible if they are identified and measured. Therefore, measuring and reporting the cost of quality (CoQ should be considered an important issue for achieving quality excellence. To collect quality costs an organization needs to adopt a framework to classify costs; however, there is no general agreement on a single broad definition of quality costs. CoQ is usually understood as the sum of conformance plus non-conformance costs, where cost of conformance is the price paid for prevention of poor quality (for example, inspection and quality appraisal and cost of non-conformance is the cost of poor quality caused by product and service failure (for example, rework and returns. The objective of this paper is to give a survey of research articles on the topic of CoQ; it opens with a literature review focused on existing CoQ models; then, it briefly presents the most common CoQ parameters and the metrics (indices used for monitoring CoQ. Finally, the use of CoQ models in practice, i.e., the implementation of a quality costing system and cost of quality reporting in companies is discussed, with emphasis in cases concerning manufacturing firms.

  14. Low Cost Manufacturing of Composite Cryotanks

    Science.gov (United States)

    Meredith, Brent; Palm, Tod; Deo, Ravi; Munafo, Paul M. (Technical Monitor)

    2002-01-01

    This viewgraph presentation reviews research and development of cryotank manufacturing conducted by Northrup Grumman. The objectives of the research and development included the development and validation of manufacturing processes and technology for fabrication of large scale cryogenic tanks, the establishment of a scale-up and facilitization plan for full scale cryotanks, the development of non-autoclave composite manufacturing processes, the fabrication of subscale tank joints for element tests, the performance of manufacturing risk reduction trials for the subscale tank, and the development of full-scale tank manufacturing concepts.

  15. Industrial Assessment Centers - Small Manufacturers Reduce Energy & Increase Productivity

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-11-06

    Since 1976, the Industrial Assessment Centers (IACs), administered by the US Department of Energy, have supported small and medium-sized American manufacturers to reduce energy use and increase their productivity and competitiveness. The 24 IACs, located at premier engineering universities around the country (see below), send faculty and engineering students to local small and medium-sized manufacturers to provide no-cost assessments of energy use, process performance and waste and water flows. Under the direction of experienced professors, IAC engineering students analyze the manufacturer’s facilities, energy bills and energy, waste and water systems, including compressed air, motors/pumps, lighting, process heat and steam. The IACs then follow up with written energy-saving and productivity improvement recommendations, with estimates of related costs and payback periods.

  16. Cost analysis of advanced turbine blade manufacturing processes

    Science.gov (United States)

    Barth, C. F.; Blake, D. E.; Stelson, T. S.

    1977-01-01

    A rigorous analysis was conducted to estimate relative manufacturing costs for high technology gas turbine blades prepared by three candidate materials process systems. The manufacturing costs for the same turbine blade configuration of directionally solidified eutectic alloy, an oxide dispersion strengthened superalloy, and a fiber reinforced superalloy were compared on a relative basis to the costs of the same blade currently in production utilizing the directional solidification process. An analytical process cost model was developed to quantitatively perform the cost comparisons. The impact of individual process yield factors on costs was also assessed as well as effects of process parameters, raw materials, labor rates and consumable items.

  17. New transmission interconnection reduces consumer costs

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2008-09-15

    The Central American electric interconnection system (SIEPAC) project will involve the construction of a 1830 km 230 kV transmission system that will link Guatemala, El Salvador, Honduras, Costa Rica, Nicaragua, and Panama. The system is expected to alleviate the region's power shortages and reduce electricity costs for consumers. Costs for the SIEPAC project have been estimated at $370 million. The system will serve approximately 37 million customers, and will include 15 substations. The contract for building the electrical equipment has been awarded to Schweitzer Engineering Laboratories (SEL) who plan to manufacture components at a plant in Mexico. The equipment will include high speed line protection, automation, and control systems. Line current differential systems and satellite-synchronized clocks will also be used. The new transmission system is expected to be fully operational by 2009. 1 fig.

  18. Manufacturing Cost Levelization Model – A User’s Guide

    Energy Technology Data Exchange (ETDEWEB)

    Morrow, William R. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Shehabi, Arman [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Smith, Sarah Josephine [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-08-01

    The Manufacturing Cost Levelization Model is a cost-performance techno-economic model that estimates total large-scale manufacturing costs for necessary to produce a given product. It is designed to provide production cost estimates for technology researchers to help guide technology research and development towards an eventual cost-effective product. The model presented in this user’s guide is generic and can be tailored to the manufacturing of any product, including the generation of electricity (as a product). This flexibility, however, requires the user to develop the processes and process efficiencies that represents a full-scale manufacturing facility. The generic model is comprised of several modules that estimate variable costs (material, labor, and operating), fixed costs (capital & maintenance), financing structures (debt and equity financing), and tax implications (taxable income after equipment and building depreciation, debt interest payments, and expenses) of a notional manufacturing plant. A cash-flow method is used to estimate a selling price necessary for the manufacturing plant to recover its total cost of production. A levelized unit sales price ($ per unit of product) is determined by dividing the net-present value of the manufacturing plant’s expenses ($) by the net present value of its product output. A user defined production schedule drives the cash-flow method that determines the levelized unit price. In addition, an analyst can increase the levelized unit price to include a gross profit margin to estimate a product sales price. This model allows an analyst to understand the effect that any input variables could have on the cost of manufacturing a product. In addition, the tool is able to perform sensitivity analysis, which can be used to identify the key variables and assumptions that have the greatest influence on the levelized costs. This component is intended to help technology researchers focus their research attention on tasks

  19. Space system production cost benefits from contemporary philosophies in management and manufacturing

    Science.gov (United States)

    Rosmait, Russell L.

    1991-01-01

    The cost of manufacturing space system hardware has always been expensive. The Engineering Cost Group of the Program Planning office at Marshall is attempting to account for cost savings that result from new technologies in manufacturing and management. The objective is to identify and define contemporary philosophies in manufacturing and management. The seven broad categories that make up the areas where technological advances can assist in reducing space system costs are illustrated. Included within these broad categories is a list of the processes or techniques that specifically provide the cost savings within todays design, test, production and operations environments. The processes and techniques listed achieve savings in the following manner: increased productivity; reduced down time; reduced scrap; reduced rework; reduced man hours; and reduced material costs. In addition, it should be noted that cost savings from production and processing improvements effect 20 to 40 pct. of production costs whereas savings from management improvements effects 60 to 80 of production cost. This is important because most efforts in reducing costs are spent trying to reduce cost in the production.

  20. Innovative manufacturing and materials for low cost lithium ion batteries

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, Steven [Optodot Corporation, Woburn, MA (United States)

    2015-12-29

    This project demonstrated entirely new manufacturing process options for lithium ion batteries with major potential for improved cost and performance. These new manufacturing approaches are based on the use of the new electrode-coated separators instead of the conventional electrode-coated metal current collector foils. The key enabler to making these electrode-coated separators is a new and unique all-ceramic separator with no conventional porous plastic separator present. A simple, low cost, and high speed manufacturing process of a single coating of a ceramic pigment and polymer binder onto a re-usable release film, followed by a subsequent delamination of the all-ceramic separator and any layers coated over it, such as electrodes and metal current collectors, was utilized. A suitable all-ceramic separator was developed that demonstrated the following required features needed for making electrode-coated separators: (1) no pores greater than 100 nanometer (nm) in diameter to prevent any penetration of the electrode pigments into the separator; (2) no shrinkage of the separator when heated to the high oven heats needed for drying of the electrode layer; and (3) no significant compression of the separator layer by the high pressure calendering step needed to densify the electrodes by about 30%. In addition, this nanoporous all-ceramic separator can be very thin at 8 microns thick for increased energy density, while providing all of the performance features provided by the current ceramic-coated plastic separators used in vehicle batteries: improved safety, longer cycle life, and stability to operate at voltages up to 5.0 V in order to obtain even more energy density. The thin all-ceramic separator provides a cost savings of at least 50% for the separator component and by itself meets the overall goal of this project to reduce the cell inactive component cost by at least 20%. The all-ceramic separator also enables further cost savings by its excellent heat stability

  1. Manufacturing R&D Initiative Lowers Costs and Boosts Quality

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-06-30

    Fact sheet that provides an overview of DOE's Manufacturing R&D Initiative, which supports projects aimed at developing better-performing, lower-cost solid-state lighting while encouraging engineering and manufacturing in the United States.

  2. Modeling of manufacturer and retailer cooperative income considering advertising costs

    Directory of Open Access Journals (Sweden)

    A.O. Zavirukha

    2013-03-01

    Full Text Available The paper represents logical block diagram of cooperative advertising costs adjustment in manufacturer and retailers logistics chain. Manufacturer and retailers joint interaction profit is considered provided linear demand function and nonlinear response function of advertising expenditures. Dimensionless variables system is introduced to form cooperative income function.

  3. Comparisons: women's garments manufacturing cost survey between Korea and China

    National Research Council Canada - National Science Library

    Myoung-Ok Kim; Youn Hee Lee; Lilian Parreiras Martins; Yingyu Wen

    2016-01-01

    .... Additionally, within the same two countries, the study surveys garment manufacturing costs, from low to high, for a both a "basic" as well as for a "detailed" blouse, pants, and jacket (total of six items...

  4. Reducing VOC Press Emission from OSB Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Gary D. McGinnis; Laura S. WIlliams; Amy E. Monte; Jagdish Rughani: Brett A. Niemi; Thomas M. Flicker

    2001-12-31

    Current regulations require industry to meet air emission standards with regard to particulates, volatile organic compounds (VOCs), hazardous air pollutants (HAPs) and other gases. One of many industries that will be affected by the new regulations is the wood composites industry. This industry generates VOCs, HAPs, and particulates mainly during the drying and pressing of wood. Current air treatment technologies for the industry are expensive to install and operate. As regulations become more stringent, treatment technologies will need to become more efficient and cost effective. The overall objective of this study is to evaluate the use of process conditions and chemical additives to reduce VOC/HAPs in air emitted from presses and dryers during the production of oriented strand board.

  5. The complexity and cost of vaccine manufacturing - An overview.

    Science.gov (United States)

    Plotkin, Stanley; Robinson, James M; Cunningham, Gerard; Iqbal, Robyn; Larsen, Shannon

    2017-07-24

    As companies, countries, and governments consider investments in vaccine production for routine immunization and outbreak response, understanding the complexity and cost drivers associated with vaccine production will help to inform business decisions. Leading multinational corporations have good understanding of the complex manufacturing processes, high technological and R&D barriers to entry, and the costs associated with vaccine production. However, decision makers in developing countries, donors and investors may not be aware of the factors that continue to limit the number of new manufacturers and have caused attrition and consolidation among existing manufacturers. This paper describes the processes and cost drivers in acquiring and maintaining licensure of childhood vaccines. In addition, when export is the goal, we describe the requirements to supply those vaccines at affordable prices to low-resource markets, including the process of World Health Organization (WHO) prequalification and supporting policy recommendation. By providing a generalized and consolidated view of these requirements we seek to build awareness in the global community of the benefits and costs associated with vaccine manufacturing and the challenges associated with maintaining consistent supply. We show that while vaccine manufacture may prima facie seem an economic growth opportunity, the complexity and high fixed costs of vaccine manufacturing limit potential profit. Further, for most lower and middle income countries a large majority of the equipment, personnel and consumables will need to be imported for years, further limiting benefits to the local economy. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  6. Cost Accounting in the Automated Manufacturing Environment

    Science.gov (United States)

    1988-06-01

    activities necessary to support production. Studies by Cooper and Kaplan (1987), and Miller and Vollman 74 (1985), suggest that many overhead costs vary with...Management, Winter 1988. Miller, J.G., and T.E. Vollman , "The Hidden Factory," Harvard Business Review, September-October 1985. Miller, S., "Industrial

  7. Cost Estimation of Laser Additive Manufacturing of Stainless Steel

    Science.gov (United States)

    Piili, Heidi; Happonen, Ari; Väistö, Tapio; Venkataramanan, Vijaikrishnan; Partanen, Jouni; Salminen, Antti

    Laser additive manufacturing (LAM) is a layer wise fabrication method in which a laser beam melts metallic powder to form solid objects. Although 3D printing has been invented 30 years ago, the industrial use is quite limited whereas the introduction of cheap consumer 3D printers, in recent years, has familiarized the 3D printing. Interest is focused more and more in manufacturing of functional parts. Aim of this study is to define and discuss the current economic opportunities and restrictions of LAM process. Manufacturing costs were studied with different build scenarios each with estimated cost structure by calculated build time and calculating the costs of the machine, material and energy with optimized machine utilization. All manufacturing and time simulations in this study were carried out with a research machine equal to commercial EOS M series equipment. The study shows that the main expense in LAM is the investment cost of the LAM machine, compared to which the relative proportions of the energy and material costs are very low. The manufacturing time per part is the key factor to optimize costs of LAM.

  8. Increase Productivity and Cost Optimization in CNC Manufacturing

    Science.gov (United States)

    Musca, Gavril; Mihalache, Andrei; Tabacaru, Lucian

    2016-11-01

    The advantage of the technological assisted design consists in easy modification of the machining technologies for obtaining machine alternation, tool changing, working parameters variation or the modification of loads to which the tools are subjected. By determining tool movement inside machining and by using tool related moving speeds needed for both positioning and manufacturing we are able to compute the required machining time for each component of the machining operation in progress. The present study describes a cost optimization model for machining operations which uses the following components: machine and its operator related cost, set-up and adjustment, unproductive costs (idle state), direct and indirect costs. By using manufacturing technologies assisted design procedures we may obtain various variants for the technological model by modifying the machining strategy, tooling, working regimes or the machine-tool that are used. Simulating those variants allows us to compare and establish the optimal manufacturing variant as well as the most productive one.

  9. Optimizing calibration intervals for specific applications to reduce maintenance costs

    Energy Technology Data Exchange (ETDEWEB)

    Collier, Steve; Holland, Jack [Servomex Group, Crowborough (United Kingdom)

    2009-11-01

    The introduction of the Servomex MultiExact 5400 analyzer has presented an opportunity to review the cost of ownership and how improvements to an analyzer's performance may be used to reduce this. Until now, gas analyzer manufacturers have taken a conservative approach to calibration intervals based on site practices and experience covering a wide range of applications. However, if specific applications are considered, then there is an opportunity to reduce costs by increasing calibration intervals. This paper demonstrates how maintenance costs may be reduced by increasing calibration intervals for those gas analyzers used for monitoring Air Separation Units (ASUs) without detracting from their performance.(author)

  10. Cost-Efficient Low-Volume Production Through Additive Manufacturing

    OpenAIRE

    Solberg, Steffen

    2016-01-01

    Additive manufacturing, commonly known as 3D Printing, is a production method of rising popularity. The method works by adding layers of material, in contrast to subtracting, which is the dominating method today. The objective of this thesis has been to evaluate the cost-efficiency of producing relatively complex parts through additive manufacturing, compared to subtractive methods with production volumes less than 20 units. Initial findings narrow the additive methods down ...

  11. Cost-Efficient Low-Volume Production Through Additive Manufacturing

    OpenAIRE

    Solberg, Steffen

    2016-01-01

    Additive manufacturing, commonly known as 3D Printing, is a production method of rising popularity. The method works by adding layers of material, in contrast to subtracting, which is the dominating method today. The objective of this thesis has been to evaluate the cost-efficiency of producing relatively complex parts through additive manufacturing, compared to subtractive methods with production volumes less than 20 units. Initial findings narrow the additive methods down ...

  12. Do hospital mergers reduce costs?

    Science.gov (United States)

    Schmitt, Matt

    2017-03-01

    Proponents of hospital consolidation claim that mergers lead to significant cost savings, but there is little systematic evidence backing these claims. For a large sample of hospital mergers between 2000 and 2010, I estimate difference-in-differences models that compare cost trends at acquired hospitals to cost trends at hospitals whose ownership did not change. I find evidence of economically and statistically significant cost reductions at acquired hospitals. On average, acquired hospitals realize cost savings between 4 and 7 percent in the years following the acquisition. These results are robust to a variety of different control strategies, and do not appear to be easily explained by post-merger changes in service and/or patient mix. I then explore several extensions of the results to examine (a) whether the acquiring hospital/system realizes cost savings post-merger and (b) if cost savings depend on the size of the acquirer and/or the geographic overlap of the merging hospitals. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Cost-effectiveness of conservation upgrades in manufactured homes

    Energy Technology Data Exchange (ETDEWEB)

    Lee, A.D.; Conner, C.C.; Englin, J.E.; Hadley, D.L.; Lucas, R.G.; Miller, N.E.; Monroe, W.H.

    1988-09-01

    This study addresses the costs of upgrading the efficiency of electrically heated manufactured homes in the Bonneville Power Administration's (Bonneville's) service territory. It was prepared by the Battelle Pacific Northwest Laboratory (PNL) for Bonneville under a Related Services Agreement with the US Department of Energy, Contract AC06-76RLO1830. Manufactured homes (commonly called mobile homes) represent a significant lost conservation resource in the region. Manufactured homes are required to meet national energy standards that do not reflect the recent increases in energy prices, and the preemptive nature of the national standards prevents local jurisdictions from establishing stricter requirements. Bonneville has undertaken several programs to analyze the efficiency of manufactured homes and encourage the industry to produce more efficient homes and consumers to increase their demand for efficient units. This study constitutes one portion of Bonneville's overall strategy. 45 refs.

  14. Reducing Supply Chain GHG Emissions from LCD Panel Manufacturing Webinar

    Science.gov (United States)

    Fluorinated greenhouse gases (F-GHGs) are among the most potent and persistent greenhouse gases contributing to global climate change. Learn about the manufacturing processes which release F-GHGs, and how LCD suppliers are working to reduce emissions.

  15. Cost modelling as decision support when locating manufacturing facilities

    Directory of Open Access Journals (Sweden)

    Christina Windmark

    2016-01-01

    Full Text Available This paper presents a methodology for cost estimation in developing decision supports for production location issues. The purpose is to provide a structured work procedure to be used by practitioners to derive the knowledge needed to make informed decisions on where to locate production. This paper present a special focus on how to integrate cost effects during the decision process. The work procedure and cost models were developed in close collaboration with a group of industrial partners. The result is a structure of cost estimation tools aligned to different steps in the work procedure. The cost models can facilitate both cost estimation for manufacturing a product under new preconditions, including support costs, and cost simulations to analyse the risks of wrong estimations and uncertainties in the input parameters. Future research aims to test the methodology in ongoing transfer projects to further understand difficulties in managing global production systems. In existing models and methods presented in the literature, cost is usually estimated on a too aggregated level to be suitable for decision support regarding production system design. The cost estimation methodology presented here provides new insights on cost driving factors related to the production system.

  16. Cost and Management Accounting Practices: A Survey of Manufacturing Companies

    Directory of Open Access Journals (Sweden)

    Ali UYAR

    2010-11-01

    Full Text Available The purpose of this study is to explore cost and management accounting practices utilized by manufacturing companies operating in Istanbul, Turkey. The sample of the study consists of 61 companies, containing both small and medium-sized enterprises, and large companies. The data collection methodology of the study is questionnaire survey. The content of the questionnaire survey is based on several previous studies. The major findings of the study are as follows: the most widely used product costing method is job costing; the complexity in production poses as the highest ranking difficulty in product costing; the most widely used three overhead allocation bases are prime costs, units produced, and direct labor cost; pricing decisions is the most important area where costing information is used; overall mean of the ratio of overhead to total cost is 34.48 percent for all industries; and the most important three management accounting practices are budgeting, planning and control, and cost-volume-profit analysis. Furthermore, decreasing profitability, increasing costs and competition, and economic crises are the factors, which increase the perceived importance of cost accounting. The findings indicate that companies perceive traditional management accounting tools still important. However, new management accounting practices such as strategic planning, and transfer pricing are perceived less important than traditional ones. Therefore, companies need to improve themselves in this aspect.

  17. Simple, cost effective & result oriented framework for supplier performance measurement in sports goods manufacturing industry

    Directory of Open Access Journals (Sweden)

    2011-09-01

    Full Text Available The emergences of global markets have increased competition worldwide. For the Sports Goods Manufacturing Industry which is considered to be an intensive supplier base industry with limited resources to sustain in what is already a very competitive market there is a need for the entire supply chain viz. raw material and machinery suppliers and manufacturers to measure their supplier's performance to reduce business risks and revenue losses. How to design & execute a simple, cost effective & result oriented Framework for Supplier Performance Measurement for sports goods manufacturing small - medium enterprises is the main aim of this research paper.

  18. New pharmaceuticals reduce cost of illness.

    Science.gov (United States)

    Hansen, R W

    1986-06-01

    The cost of illness includes not only the funds required to treat illness, but also the effect on the patient's quality of life. Recent concern about rising health costs have focused on the direct expenditures without noting that the cost of illness in terms of mortality and morbidity has declined significantly. Pharmaceuticals have played a major role in reducing the total cost of illness. Several studies of the cost-effectiveness of past introductions of vaccines and pharmaceuticals reveal large cost savings. Although the focus of most studies has been on major advances, the continuing process of less dramatic therapeutic improvements has significantly trimmed the cost of illness. Cost-benefit studies of new drugs or changes in drug use, while more difficult to perform, make it possible to influence the selection of therapy. Since pharmaceuticals represent less than 10% of total treatment costs, reduction in the cost of pharmaceutical products can only have a minor impact on the total cost of illness. Pharmaceuticals can reduce the cost of illness by providing alternative therapies that reduce direct treatment cost or improve the public health.

  19. Transaction Costs in Global Supply Chains of Manufacturing Companies

    Directory of Open Access Journals (Sweden)

    Philipp Bremen

    2010-02-01

    Full Text Available Outsourcing has advanced to an important measure that is applied broadly in operations management. Nowadays, suppliers of manufacturing companies do not only provide direct material like raw material and operational supplements but offer components and advanced modules incurring many value-adding stages. Whereas in the past companies built up local supplier networks, they recently tend to search for global sources. However, not all companies reach their expectations towards the success of global sourcing projects. Important reasons for relocating manufacturing capacities back to local suppliers or in- house manufacturing are costs for unexpected coordination activities, limited flexibility and declined or fluctuating quality. The theory of Transaction Cost Economics postulates that transaction costs of the types information, communication and coordination determine the governance structure of a supply chain, i.e. market, hybrid or firm. The objective of this paper is to analyze the cause-and-effect chain of inter-firm transaction costs concerning global sourcing. The resulting qualitative model is based on explorative multiple-case study.

  20. Costing support and cost control in manufacturing. A cost estimation tool applied in the sheet metal domain.

    OpenAIRE

    ten Brinke, E.

    2002-01-01

    In the product development cycle several engineering tasks like design, process planning and production planning have to be executed. The execution of these tasks mainly involves information processing and decision-making. Because costs is an important factor in manufacturing, adequate information about costs is extremely valuable for all engineering tasks. Therefore, a cost estimation system for the generation of cost information and for cost control, integrated in the product development cy...

  1. Reducing energy costs in nursing homes

    Energy Technology Data Exchange (ETDEWEB)

    1981-01-01

    The handbook presents ideas and techniques for energy conservation in nursing homes. Case studies were developed of nursing homes located in different parts of the US. The typical nursing home assessed was proprietary, of intermediate-care level, medicaid-certified, and had less than 200 beds. Specific energy conservation measures were analyzed to determine the energy and dollar savings that could be realized. These include reducing heat loss through the building shell; reducing hot water costs; recovering the heat generated by dryers; reducing lighting costs; reducing heating and cooling costs, and analyzing fuels and fuel rates. A case for converting electric clothes dryers to gas was analyzed. (MCW)

  2. Cost models of additive manufacturing: A literature review

    Directory of Open Access Journals (Sweden)

    G. Costabile

    2016-11-01

    Full Text Available From the past decades, increasing attention has been paid to the quality level of technological and mechanical properties achieved by the Additive Manufacturing (AM; these two elements have achieved a good performance, and it is possible to compare this with the results achieved by traditional technology. Therefore, the AM maturity is high enough to let industries adopt this technology in a more general production framework as the mechanical manufacturing industrial one is. Since the technological and mechanical properties are also beneficial for the materials produced with AM, the primary objective of this paper is to focus more on managerial facets, such as the cost control of a production environment, where these new technologies are present. This paper aims to analyse the existing literature about the cost models developed specifically for AM from an operations management point of view and discusses the strengths and weaknesses of all models.

  3. Identification of complexity cost factors in manufacturing companies

    DEFF Research Database (Denmark)

    Myrodia, Anna; Hvam, Lars

    2015-01-01

    . This research focuses on the relation between product and process complexity. Complexity cost factors are identified and categorized under the industrial standard APQC for process classification. Then, this categorization is used as a tool for identification of complexity cost factors in seven companies......Complexity tends to be arguably the biggest challenge of manufacturing companies. As the demand from the customers increases in volume and diversity, the number of finished products and components increases as well. This increasing product complexity has a direct effect on the production processes...

  4. Advanced Drying Process for Lower Manufacturing Cost of Electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Ahmad, Iftikhar [Lambda Technologies, Inc., Morrisville, NC (United States); Zhang, Pu [Lambda Technologies, Inc., Morrisville, NC (United States)

    2016-11-30

    the electrode materials. For the existing electrode materials, the material analysis and cell characterization data from ADP dried electrodes showed equivalent (or slightly better) performance. However, for high loading and thicker electrode materials (for high energy densities) the ADP advantages are more prominent. There was less binder migration, the resistance was lower hence the current capacities and retention of the battery cells were higher. The success of the project has enabled credible communications with commercial end users as well as battery coating line integrators. Goal is to scale ADP up for high volume manufacturing of Li-ion battery electrodes. The implementation of ADP in high volume manufacturing will reduce a high cost production step to bring the overall price of Li-ion batteries down. This will ultimately have a positive impact on the public by making electric and hybrid vehicles more affordable.

  5. Cost analysis of composite fan blade manufacturing processes

    Science.gov (United States)

    Stelson, T. S.; Barth, C. F.

    1980-01-01

    The relative manufacturing costs were estimated for large high technology fan blades prepared by advanced composite fabrication methods using seven candidate materials/process systems. These systems were identified as laminated resin matrix composite, filament wound resin matrix composite, superhybrid solid laminate, superhybrid spar/shell, metal matrix composite, metal matrix composite with a spar and shell, and hollow titanium. The costs were calculated utilizing analytical process models and all cost data are presented as normalized relative values where 100 was the cost of a conventionally forged solid titanium fan blade whose geometry corresponded to a size typical of 42 blades per disc. Four costs were calculated for each of the seven candidate systems to relate the variation of cost on blade size. Geometries typical of blade designs at 24, 30, 36 and 42 blades per disc were used. The impact of individual process yield factors on costs was also assessed as well as effects of process parameters, raw materials, labor rates and consumable items.

  6. Reducing the Cost of Solar Cells

    Energy Technology Data Exchange (ETDEWEB)

    Scanlon, B.

    2012-04-01

    Solar-powered electricity prices could soon approach those of power from coal or natural gas thanks to collaborative research with solar startup Ampulse Corporation at the National Renewable Energy Laboratory. Silicon wafers account for almost half the cost of today's solar photovoltaic panels, so reducing or eliminating wafer costs is essential to bringing prices down. Current crystalline silicon technology converts energy in a highly efficient manner; however, that technology is manufactured with processes that could stand some improvement. The industry needs a method that is less complex, creates less waste and uses less energy. First, half the refined silicon is lost as dust in the wafer-sawing process, driving module costs higher. Wafers are sawn off of large cylindrical ingots, or boules, of silicon. A typical 2-meter boule loses as many as 6,000 potential wafers during sawing. Second, the wafers produced are much thicker than necessary. To efficiently convert sunlight into electricity, the wafers need be only one-tenth the typical thickness. NREL, the Oak Ridge National Laboratory and Ampulse have partnered on an approach to eliminate this waste and dramatically lower the cost of the finished solar panels. By using a chemical vapor deposition process to grow the silicon on inexpensive foil, Ampulse is able to make the solar cells just thick enough to convert most of the solar energy into electricity. No more sawdust - and no more wasting refined silicon materials. NREL developed the technology to grow high-quality silicon and ORNL developed the metal foil that has the correct crystal structure to support that growth. Ampulse is installing a pilot manufacturing line in NREL's Process Development Integration Laboratory, where solar companies can work closely with lab scientists on integrated equipment to answer pressing questions related to their technology development, as well as rapidly overcoming R and D challenges and risk. NREL's program is

  7. Prospects for reducing the processing cost of lithium ion batteries

    Science.gov (United States)

    Wood, David L.; Li, Jianlin; Daniel, Claus

    2015-02-01

    A detailed processing cost breakdown is given for lithium-ion battery (LIB) electrodes, which focuses on: 1) elimination of toxic, costly N-methylpyrrolidone (NMP) dispersion chemistry; 2) doubling the thicknesses of the anode and cathode to raise energy density; and 3) reduction of the anode electrolyte wetting and SEI-layer formation time. These processing cost reduction technologies generically adaptable to any anode or cathode cell chemistry and are being implemented at ORNL. This paper shows step by step how these cost savings can be realized in existing or new LIB manufacturing plants using a baseline case of thin (power) electrodes produced with NMP processing and a standard 10-14-day wetting and formation process. In particular, it is shown that aqueous electrode processing can cut the electrode processing cost and energy consumption by an order of magnitude. Doubling the thickness of the electrodes allows for using half of the inactive current collectors and separators, contributing even further to the processing cost savings. Finally wetting and SEI-layer formation cost savings are discussed in the context of a protocol with significantly reduced time. These three benefits collectively offer the possibility of reducing LIB pack cost from 502.8 kW h-1-usable to 370.3 kW h-1-usable, a savings of 132.5/kWh (or 26.4%).

  8. A Modified Cost Estimation Formulae for Calculating Manufacturing Cost of Injection Part/Mold

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In modern society, a plastic part has its own important position. To the managers and decision-makers in the field of plastic component, how to decide the manufacturing cost of the injection part or injection mold as quickly as possible is most valuable. Cost estimation formulae (CEF) are the most common method to evaluate the cost of injection part/mold, which is similar to our ordinary thinking. In this paper, a CEF method used by Dr. Weiyi Hu in Massachusetts University is first discussed. To the problems existed in the formulae, we propose an improved algorithm. This algorithm can be used to estimate the manufacturing cost of injection part/mold accurately in the early design stage.

  9. Innovative manufacturing technologies for low-cost, high efficiency PERC-based PV modules

    Energy Technology Data Exchange (ETDEWEB)

    Yelundur, Vijay [Suniva Inc., Norcross, GA (United States)

    2017-04-19

    The goal this project was to accelerate the deployment of innovative solar cell and module technologies that reduce the cost of PERC-based modules to best-in-class. New module integration technology was to be used to reduce the cost and reliance on conventional silver bus bar pastes and enhance cell efficiency. On the cell manufacturing front, the cost of PERC solar cells was to be reduced by introducing advanced metallization approaches to increase cell efficiency. These advancements will be combined with process optimization to target cell efficiencies in the range of 21 to 21.5%. This project will also explore the viability of a bifacial PERC solar cell design to enable cost savings through the use of thin silicon wafers. This project was terminated on 4/30/17 after four months of activity due financial challenges facing the recipient.

  10. A KBE genetic-causal cost modelling methodology for manufacturing cost contingency management

    NARCIS (Netherlands)

    Curran, R.; Gilmour, M.; McAlleean, C.; Kelly, P.

    2009-01-01

    The paper provides validated evidence of a robust methodology for the management of lean manufacturing cost contingency, with a particular focus on contingency regarding recurring work content. A truly concurrent engineering process is established by capturing a range of knowledge from the design, m

  11. A KBE genetic-causal cost modelling methodology for manufacturing cost contingency management

    NARCIS (Netherlands)

    Curran, R.; Gilmour, M.; McAlleean, C.; Kelly, P.

    2009-01-01

    The paper provides validated evidence of a robust methodology for the management of lean manufacturing cost contingency, with a particular focus on contingency regarding recurring work content. A truly concurrent engineering process is established by capturing a range of knowledge from the design,

  12. Cost analysis methodology: Photovoltaic Manufacturing Technology Project. Annual subcontract report, 11 March 1991--11 November 1991

    Energy Technology Data Exchange (ETDEWEB)

    Whisnant, R.A. [Research Triangle Inst., Research Triangle Park, NC (United States)

    1992-09-01

    This report describes work done under Phase 1 of the Photovoltaic Manufacturing Technology (PVMaT) Project. PVMaT is a five-year project to support the translation of research and development in PV technology into the marketplace. PVMaT, conceived as a DOE/industry partnership, seeks to advanced PV manufacturing technologies, reduce PV module production costs, increase module performance, and expand US commercial production capacities. Under PVMaT, manufacturers will propose specific manufacturing process improvements that may contribute to the goals of the project, which is to lessen the cost, thus hastening entry into the larger scale, grid-connected applications. Phase 1 of the PVMaT project is to identify obstacles and problems associated with manufacturing processes. This report describes the cost analysis methodology required under Phase 1 that will allow subcontractors to be ranked and evaluated during Phase 2.

  13. Cost comparisons for the use of nonterrestrial materials in space manufacturing of large structures

    Science.gov (United States)

    Bock, E. H.; Risley, R. C.

    1979-01-01

    This paper presents results of a study sponsored by NASA to evaluate the relative merits of constructing solar power satellites (SPS) using resources obtained from the earth and from the moon. Three representative lunar resources utilization (LRU) concepts are developed and compared with a previously defined earth baseline concept. Economic assessment of the alternatives includes cost determination, economic threshold sensitivity to manufacturing cost variations, cost uncertainties, program funding schedule, and present value of costs. Results indicate that LRU for space construction is competitive with the earth baseline approach for a program requiring 100,000 metric tons per year of completed satellites. LRU can reduce earth-launched cargo requirements to less than 10% of that needed to build satellites exclusively from earth materials. LRU is potentially more cost-effective than earth-derived material utilization, due to significant reductions in both transportation and manufacturing costs. Because of uncertainties, cost-effectiveness cannot be ascertained with great confidence. The probability of LRU attaining a lower total program cost within the 30-year program appears to range from 57 to 93%.

  14. Automated packaging platform for low-cost high-performance optical components manufacturing

    Science.gov (United States)

    Ku, Robert T.

    2004-05-01

    Delivering high performance integrated optical components at low cost is critical to the continuing recovery and growth of the optical communications industry. In today's market, network equipment vendors need to provide their customers with new solutions that reduce operating expenses and enable new revenue generating IP services. They must depend on the availability of highly integrated optical modules exhibiting high performance, small package size, low power consumption, and most importantly, low cost. The cost of typical optical system hardware is dominated by linecards that are in turn cost-dominated by transmitters and receivers or transceivers and transponders. Cost effective packaging of optical components in these small size modules is becoming the biggest challenge to be addressed. For many traditional component suppliers in our industry, the combination of small size, high performance, and low cost appears to be in conflict and not feasible with conventional product design concepts and labor intensive manual assembly and test. With the advent of photonic integration, there are a variety of materials, optics, substrates, active/passive devices, and mechanical/RF piece parts to manage in manufacturing to achieve high performance at low cost. The use of automation has been demonstrated to surpass manual operation in cost (even with very low labor cost) as well as product uniformity and quality. In this paper, we will discuss the value of using an automated packaging platform.for the assembly and test of high performance active components, such as 2.5Gb/s and 10 Gb/s sources and receivers. Low cost, high performance manufacturing can best be achieved by leveraging a flexible packaging platform to address a multitude of laser and detector devices, integration of electronics and handle various package bodies and fiber configurations. This paper describes the operation and results of working robotic assemblers in the manufacture of a Laser Optical Subassembly

  15. Manufacturing enterprise’s logistics operational cost simulation and optimization from the perspective of inter-firm network

    Directory of Open Access Journals (Sweden)

    Chun Fu

    2015-05-01

    Full Text Available Purpose: By studying the case of a Changsha engineering machinery manufacturing firm, this paper aims to find out the optimization tactics to reduce enterprise’s logistics operational cost. Design/methodology/approach: This paper builds the structure model of manufacturing enterprise’s logistics operational costs from the perspective of inter-firm network and simulates the model based on system dynamics. Findings: It concludes that applying system dynamics in the research of manufacturing enterprise’s logistics cost control can better reflect the relationship of factors in the system. And the case firm can optimize the logistics costs by implement joint distribution. Research limitations/implications: This study still lacks comprehensive consideration about the variables quantities and quantitative of the control factors. In the future, we should strengthen the collection of data and information about the engineering manufacturing firms and improve the logistics operational cost model. Practical implications: This study puts forward some optimization tactics to reduce enterprise’s logistics operational cost. And it is of great significance for enterprise’s supply chain management optimization and logistics cost control. Originality/value: Differing from the existing literatures, this paper builds the structure model of manufacturing enterprise’s logistics operational costs from the perspective of inter-firm network and simulates the model based on system dynamics.

  16. Costs of emission-reducing manure application

    NARCIS (Netherlands)

    Huijsmans, J.F.M.; Verwijs, B.; Rodhe, L.; Smith, K.

    2004-01-01

    Favourable economics of handling and application of manure are of fundamental importance to encourage the implementation of emission-reducing application techniques. The economics of manure application depend on the costs of the equipment and the time to carry out the field operation. In this study

  17. Manufacturing cost reductions and ecoefficiency: a relationship based on a case study

    Directory of Open Access Journals (Sweden)

    Rosangela Maria Vanalle

    2014-12-01

    Full Text Available In the search for higher profits or competitiveness, firms have frequently used structured procedures to reduce their costs and expenses. However, the environmental consequences associated to those processes have hardly been considered. Hence, the central purpose of this paper is to show that it is possible to obtain relevant environmental gains even not considering the environmental issues as part of the operational cost reduction efforts. This particular point was verified through a single case study where value analysis was used to obtain manufacturing cost reductions in a company belonging to the Brazilian textile sector. Even not considering environmental aspects as part of the value analysis procedures, when the cost reduction actions were implemented it was possible to confirm that they also brought significant improvements to the environmental conditions, which were measured by the firm ecoefficiency levels before and after the cost reduction implementations. Normal 0 21 false false false PT-BR X-NONE X-NONE

  18. DEVELOPMENT AND MANUFACTURE OF COST EFFECTIVE COMPOSITE DRILL PIPE

    Energy Technology Data Exchange (ETDEWEB)

    James C. Leslie; Jeffrey R. Jean; Hans Neubert; Lee Truong

    2001-10-30

    This technical report presents the engineering research and data accomplishments that have transpired to date in support of the development of Cost Effective Composite Drill Pipe (CDP). The report discusses and illustrates all progress in the first two years of this NETL/DOE supported program. The following have been accomplished and are reported in detail herein: (1) Specifications for both 5 5/16 inch and 3 3/8 inch composite drill pipe have been finalized. (2) All basic laboratory testing has been completed and has provide sufficient data for the selection of materials for the composite tubing, adhesives, and abrasion coatings. (3) Successful demonstration of composite/metal joint interfacial connection. (4) Upgrade of facilities to provide a functional pilot plant manufacturing facility. (5) Arrangements to have the 3 3/8 inch CDP used in a drilling operation early in C.Y. 2002. (6) Arrangements to have the 5 5/16 inch CDP marketed and produced by a major drill pipe manufacturer.

  19. Design and manufacture of a low cost educational hexapod rover

    Science.gov (United States)

    Candini, Gian Paolo; Paolini, Emanuele; Piergentili, Fabrizio

    2009-08-01

    The paper deals with the design and realization of a hexapod rover prototype completely manufactured by students and researchers of the Space Robotics Group of the II Faculty of Engineering of the University of Bologna "ALMA MATER". The rover project has been developed for didactical purposes, with the aim of involving students in practical, hands-on education, pushing them to face real problems and to put in practice what they have learnt in theory during regular courses. The work done is described in the paper, highlighting its potential to test different solutions in autonomous navigation systems: low-cost sensors, innovative algorithms and different step procedures. Moreover, the mechanical and electronic solutions adopted for leg design, main controller, and remote control are discussed and depicted in the paper.

  20. Low-cost manufacturing of the point focus concentrating module and its key component, the Fresnel lens. Final subcontract report, 31 January 1991--6 May 1991

    Energy Technology Data Exchange (ETDEWEB)

    Saifee, T.; Konnerth, A. III [Solar Kinetics, Inc., Dallas, TX (United States)

    1991-11-01

    Solar Kinetics, Inc. (SKI) has been developing point-focus concentrating PV modules since 1986. SKI is currently in position to manufacture between 200 to 600 kilowatts annually of the current design by a combination of manual and semi-automated methods. This report reviews the current status of module manufacture and specifies the required approach to achieve a high-volume manufacturing capability and low cost. The approach taken will include process development concurrent with module design for automated manufacturing. The current effort reviews the major manufacturing costs and identifies components and processes whose improvements would produce the greatest effect on manufacturability and cost reduction. The Fresnel lens is one such key component. Investigating specific alternative manufacturing methods and sources has substantially reduced the lens costs and has exceeded the DOE cost-reduction goals. 15 refs.

  1. Costing support and cost control in manufacturing. A cost estimation tool applied in the sheet metal domain.

    NARCIS (Netherlands)

    Brinke, ten Erik

    2002-01-01

    In the product development cycle several engineering tasks like design, process planning and production planning have to be executed. The execution of these tasks mainly involves information processing and decision-making. Because costs is an important factor in manufacturing, adequate information a

  2. Costing support and cost control in manufacturing. A cost estimation tool applied in the sheet metal domain.

    NARCIS (Netherlands)

    ten Brinke, E.

    2002-01-01

    In the product development cycle several engineering tasks like design, process planning and production planning have to be executed. The execution of these tasks mainly involves information processing and decision-making. Because costs is an important factor in manufacturing, adequate information

  3. Development and Manufacture of Cost-Effective Composite Drill Pipe

    Energy Technology Data Exchange (ETDEWEB)

    James C. Leslie

    2008-12-31

    Advanced Composite Products and Technology, Inc. (ACPT) has developed composite drill pipe (CDP) that matches the structural and strength properties of steel drill pipe, but weighs less than 50 percent of its steel counterpart. Funding for the multiyear research and development of CDP was provided by the U.S. Department of Energy Office of Fossil Energy through the Natural Gas and Oil Projects Management Division at the National Energy Technology Laboratory (NETL). Composite materials made of carbon fibers and epoxy resin offer mechanical properties comparable to steel at less than half the weight. Composite drill pipe consists of a composite material tube with standard drill pipe steel box and pin connections. Unlike metal drill pipe, composite drill pipe can be easily designed, ordered, and produced to meet specific requirements for specific applications. Because it uses standard joint connectors, CDP can be used in lieu of any part of or for the entire steel drill pipe section. For low curvature extended reach, deep directional drilling, or ultra deep onshore or offshore drilling, the increased strength to weight ratio of CDP will increase the limits in all three drilling applications. Deceased weight will reduce hauling costs and increase the amount of drill pipe allowed on offshore platforms. In extreme extended reach areas and high-angle directional drilling, drilling limits are associated with both high angle (fatigue) and frictional effects resulting from the combination of high angle curvature and/or total weight. The radius of curvature for a hole as small as 40 feet (12.2 meters) or a build rate of 140 degrees per 100 feet is within the fatigue limits of specially designed CDP. Other properties that can be incorporated into the design and manufacture of composite drill pipe and make it attractive for specific applications are corrosion resistance, non-magnetic intervals, and abrasion resistance coatings. Since CDP has little or no electromagnetic force

  4. Costs of reducing nutrient losses in Denmark

    DEFF Research Database (Denmark)

    Jacobsen, Brian H.; Abildtrup, Jens; Jensen, Jørgen Dejgård

    to the eastern part of Denmark. The final plan for the Aquatic Environment III from 2004 included a 13% reduction of N-leaching until 2015 based on cost effective administrative measures like wetlands and catch crops. Also a tax on mineral phosphorus in feedstuffs was included in order to half the phosphorus......The economic calculations carried out prior to the Plan for the Aquatic Environment III included a comparison of regulation systems aimed at reducing nitrogen leaching, analyses of measures for reducing phosphorus losses and estimation of administrative costs. The conclusions were that taxation...... surplus. The measures in the Plan will have to be supplemented by more measures to meet the targets in the EU's Water Framework Directive....

  5. 48 CFR 31.205-25 - Manufacturing and production engineering costs.

    Science.gov (United States)

    2010-10-01

    ... production engineering costs. 31.205-25 Section 31.205-25 Federal Acquisition Regulations System FEDERAL... Commercial Organizations 31.205-25 Manufacturing and production engineering costs. (a) The costs of manufacturing and production engineering effort as described in (1) through (4) below are all allowable: (1...

  6. An Application of Six Sigma to Reduce Supplier Quality Cost

    Science.gov (United States)

    Gaikwad, Lokpriya Mohanrao; Teli, Shivagond Nagappa; Majali, Vijay Shashikant; Bhushi, Umesh Mahadevappa

    2016-01-01

    This article presents an application of Six Sigma to reduce supplier quality cost in manufacturing industry. Although there is a wider acceptance of Six Sigma in many organizations today, there is still a lack of in-depth case study of Six Sigma. For the present research the case study methodology was used. The company decided to reduce quality cost and improve selected processes using Six Sigma methodologies. Regarding the fact that there is a lack of case studies dealing with Six Sigma especially in individual manufacturing organization this article could be of great importance also for the practitioners. This paper discusses the quality and productivity improvement in a supplier enterprise through a case study. The paper deals with an application of Six Sigma define-measure-analyze-improve-control methodology in an industry which provides a framework to identify, quantify and eliminate sources of variation in an operational process in question, to optimize the operation variables, improve and sustain performance viz. process yield with well-executed control plans. Six Sigma improves the process performance (process yield) of the critical operational process, leading to better utilization of resources, decreases variations and maintains consistent quality of the process output.

  7. Low Cost Injection Mold Creation via Hybrid Additive and Conventional Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Dehoff, Ryan R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Watkins, Thomas R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); List, III, Frederick Alyious [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Carver, Keith [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); England, Roger [Cummins, Inc, Knoxville, TN (United States)

    2015-12-01

    The purpose of the proposed project between Cummins and ORNL is to significantly reduce the cost of the tooling (machining and materials) required to create injection molds to make plastic components. Presently, the high cost of this tooling forces the design decision to make cast aluminum parts because Cummins typical production volumes are too low to allow injection molded plastic parts to be cost effective with the amortized cost of the injection molding tooling. In addition to reducing the weight of components, polymer injection molding allows the opportunity for the alternative cooling methods, via nitrogen gas. Nitrogen gas cooling offers an environmentally and economically attractive cooling option, if the mold can be manufactured economically. In this project, a current injection molding design was optimized for cooling using nitrogen gas. The various components of the injection mold tooling were fabricated using the Renishaw powder bed laser additive manufacturing technology. Subsequent machining was performed on the as deposited components to form a working assembly. The injection mold is scheduled to be tested in a projection setting at a commercial vendor selected by Cummins.

  8. Rapid cost-effective silicon carbide optical component manufacturing technique

    Science.gov (United States)

    Casstevens, John M.; Plummer, Ronald; Jarocki, Jim

    1999-10-01

    Silicon carbide may well be the best known material for the manufacture of high performance optical components. A combination of extremely high specific stiffness (r/E), high thermal conductivity and outstanding dimensional stability make silicon carbide superior overall to beryllium and low- expansion glass ceramics. A major impediment to wide use of silicon carbide in optical systems has been the costs of preliminary pressing, casting, shaping and final finishing of silicon carbide. Diamond grinding of silicon carbide is a slow and expensive process even on machines specially designed for the task. The process described here begins by machining the component from a special type of graphite. This graphite is easily machined with multi-axis CNC machine tools to any level of complexity and lightweighting required. The graphite is then converted completely to silicon carbide with very small and very predictable dimensional change. After conversion to silicon carbide the optical surface is coated with very fine grain silicon carbide which is easily polished to extreme smoothness using conventional optical polishing techniques. The fabrication process and a 6 inch diameter development mirror is described.

  9. Analysis of Wooden Toy Manufacturing Costs Through the Application of a Time-Driven Activity-Based Costing System

    OpenAIRE

    PONGWASIT, Ramida; CHOMPU-INWAI, Rungchat

    2016-01-01

    The case study company, which manufactures wooden toys, encounters problems when fixing its product prices, since its experienced owners tend to dictate the prices of all the products, yet do not have available the appropriate product price and cost data. Currently, the company’s product costs are calculated using traditional accounting methods, but these are unable to accurately record the costs associated with the resources used and activities that occur during manufacture. Furthermore, whe...

  10. Good Manufacturing Practices (GMP) manufacturing of advanced therapy medicinal products: a novel tailored model for optimizing performance and estimating costs.

    Science.gov (United States)

    Abou-El-Enein, Mohamed; Römhild, Andy; Kaiser, Daniel; Beier, Carola; Bauer, Gerhard; Volk, Hans-Dieter; Reinke, Petra

    2013-03-01

    Advanced therapy medicinal products (ATMP) have gained considerable attention in academia due to their therapeutic potential. Good Manufacturing Practice (GMP) principles ensure the quality and sterility of manufacturing these products. We developed a model for estimating the manufacturing costs of cell therapy products and optimizing the performance of academic GMP-facilities. The "Clean-Room Technology Assessment Technique" (CTAT) was tested prospectively in the GMP facility of BCRT, Berlin, Germany, then retrospectively in the GMP facility of the University of California-Davis, California, USA. CTAT is a two-level model: level one identifies operational (core) processes and measures their fixed costs; level two identifies production (supporting) processes and measures their variable costs. The model comprises several tools to measure and optimize performance of these processes. Manufacturing costs were itemized using adjusted micro-costing system. CTAT identified GMP activities with strong correlation to the manufacturing process of cell-based products. Building best practice standards allowed for performance improvement and elimination of human errors. The model also demonstrated the unidirectional dependencies that may exist among the core GMP activities. When compared to traditional business models, the CTAT assessment resulted in a more accurate allocation of annual expenses. The estimated expenses were used to set a fee structure for both GMP facilities. A mathematical equation was also developed to provide the final product cost. CTAT can be a useful tool in estimating accurate costs for the ATMPs manufactured in an optimized GMP process. These estimates are useful when analyzing the cost-effectiveness of these novel interventions. Copyright © 2013 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.

  11. Reducing Financing Costs for Federal ESPCs

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, P.J.

    2005-01-28

    This report documents the recommendations of a working group commissioned by the Federal Energy Management Program (FEMP) in 2002 to identify ways to reduce financing costs in federal energy savings performance contract (ESPC) projects. The working group is part of continuing efforts launched by FEMP since the award of the Department of Energy's (DOE's) Super ESPCs in 1998 and 1999 to ensure that practical, flexible, and cost-effective alternative financing for energy-efficiency improvements is available to all federal agencies. During FY 2002-2004, the working group pursued extensive fact finding, consulted with government and private-sector finance experts, and analyzed data from federal and local government ESPC programs. The working group observed that both competition and transparency were lacking in federal ESPCs. The working group also found that the government often falls short of full compliance with certain provisions of the final rule that codifies the federal ESPC authority into regulation (10 CFR 436), which speak to due diligence in determining fair and reasonable pricing. Based on these findings, the working group formulated their short-term recommendations of actions that agencies can take immediately to reduce ESPC financing costs. The working group recommended requiring competitive solicitation of offers from prospective financiers of ESPC projects, standardization of processes to keep the playing field level and reduce energy service companies (ESCOs) project development costs, and assuring transparency by specifying that the government will see and review all bids. The reforms are intended to enable the government to determine quickly and reliably whether the portion of price related to financing is fair and reasonable and to provide auditable records of the transaction. The working group's recommendations were incorporated into modifications to the Super ESPCs and requirements to be included in the Super ESPC delivery order

  12. Low Cost Method of Manufacturing Cooled Axisymmetric Scramjets Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Scramjet engine developers are working on advanced axisymmetric engine concepts that may not be feasible due to limitations of currently available manufacturing...

  13. Automotive Lithium-ion Cell Manufacturing: Regional Cost Structures and Supply Chain Considerations

    Energy Technology Data Exchange (ETDEWEB)

    Donald Chung, Emma Elgqvist, and Shriram Santhanagopalan

    2016-04-01

    Manufacturing capacity for lithium-ion batteries (LIBs) — which power many consumer electronics and are increasingly used to power electric vehicles — is heavily concentrated in East Asia. To illuminate the factors that drive regional competitiveness in automotive LIB cell production, this study models cell manufacturing cost and minimum sustainable price, and examines development of LIB supply chains and current LIB market conditions. The study shows that factors driving the cost competitiveness of LIB manufacturing locations are mostly built—supply chain developments and competition, access to materials, and production expertise. Some regional costs — including cost of capital, labor, and materials — are significant and should be considered.

  14. PEM fuel cell cost minimization using ``Design For Manufacture and Assembly`` techniques

    Energy Technology Data Exchange (ETDEWEB)

    Lomax, F.D. Jr.; James, B.D. [Directed Technologies, Inc., Arlington, VA (United States); Mooradian, R.P. [Ford Motor Co., Dearborn, MI (United States)

    1997-12-31

    Polymer Electrolyte Membrane (PEM) fuel cells fueled with direct hydrogen have demonstrated substantial technical potential to replace Internal Combustion Engines (ICE`s) in light duty vehicles. Such a transition to a hydrogen economy offers the potential of substantial benefits from reduced criteria and greenhouse emissions as well as reduced foreign fuel dependence. Research conducted for the Ford Motor Co. under a US Department of Energy contract suggests that hydrogen fuel, when used in a fuel cell vehicle (FCV), can achieve a cost per vehicle mile less than or equal to the gasoline cost per mile when used in an ICE vehicle. However, fuel cost parity is not sufficient to ensure overall economic success: the PEM fuel cell power system itself must be of comparable cost to the ICE. To ascertain if low cost production of PEM fuel cells is feasible, a powerful set of mechanical engineering tools collectively referred to as Design for Manufacture and Assembly (DFMA) has been applied to several representative PEM fuel cell designs. The preliminary results of this work are encouraging, as presented.

  15. Manufacturing High-Quality Carbon Nanotubes at Lower Cost

    Science.gov (United States)

    Benavides, Jeanette M.; Lidecker, Henning

    2004-01-01

    A modified electric-arc welding process has been developed for manufacturing high-quality batches of carbon nanotubes at relatively low cost. Unlike in some other processes for making carbon nanotubes, metal catalysts are not used and, consequently, it is not necessary to perform extensive cleaning and purification. Also, unlike some other processes, this process is carried out at atmospheric pressure under a hood instead of in a closed, pressurized chamber; as a result, the present process can be implemented more easily. Although the present welding-based process includes an electric arc, it differs from a prior electric-arc nanotube-production process. The welding equipment used in this process includes an AC/DC welding power source with an integral helium-gas delivery system and circulating water for cooling an assembly that holds one of the welding electrodes (in this case, the anode). The cathode is a hollow carbon (optionally, graphite) rod having an outside diameter of 2 in. (approximately equal to 5.1 cm) and an inside diameter of 5/8 in. (approximately equal to 1.6 cm). The cathode is partly immersed in a water bath, such that it protrudes about 2 in. (about 5.1 cm) above the surface of the water. The bottom end of the cathode is held underwater by a clamp, to which is connected the grounding cable of the welding power source. The anode is a carbon rod 1/8 in. (approximately equal to 0.3 cm) in diameter. The assembly that holds the anode includes a thumbknob- driven mechanism for controlling the height of the anode. A small hood is placed over the anode to direct a flow of helium downward from the anode to the cathode during the welding process. A bell-shaped exhaust hood collects the helium and other gases from the process. During the process, as the anode is consumed, the height of the anode is adjusted to maintain an anode-to-cathode gap of 1 mm. The arc-welding process is continued until the upper end of the anode has been lowered to a specified height

  16. transportation cost minimization of a manufacturing firm using ...

    African Journals Online (AJOL)

    user

    The obtained data were analyzed and formulated into a transportation matrix with ... manufacturing organization as even the best product ... relationship between the representation of structures ... problem using the concept of spanning trees.

  17. Flat plate vs. concentrator solar photovoltaic cells - A manufacturing cost analysis

    Science.gov (United States)

    Granon, L. A.; Coleman, M. G.

    1980-01-01

    The choice of which photovoltaic system (flat plate or concentrator) to use for utilizing solar cells to generate electricity depends mainly on the cost. A detailed, comparative manufacturing cost analysis of the two types of systems is presented. Several common assumptions, i.e., cell thickness, interest rate, power rate, factory production life, polysilicon cost, and direct labor rate are utilized in this analysis. Process sequences, cost variables, and sensitivity analyses have been studied, and results of the latter show that the most important parameters which determine manufacturing costs are concentration ratio, manufacturing volume, and cell efficiency. The total cost per watt of the flat plate solar cell is $1.45, and that of the concentrator solar cell is $1.85, the higher cost being due to the increased process complexity and material costs.

  18. Development of advanced manufacturing technologies for low cost hydrogen storage vessels

    Energy Technology Data Exchange (ETDEWEB)

    Leavitt, Mark [Quantum Fuel Systems Technologies Worldwide, Inc., Irvine, CA (United States); Lam, Patrick [Boeing Research and Technology (BR& T), Seattle, WA (United States)

    2014-12-29

    The U.S. Department of Energy (DOE) defined a need for low-cost gaseous hydrogen storage vessels at 700 bar to support cost goals aimed at 500,000 units per year. Existing filament winding processes produce a pressure vessel that is structurally inefficient, requiring more carbon fiber for manufacturing reasons, than would otherwise be necessary. Carbon fiber is the greatest cost driver in building a hydrogen pressure vessel. The objective of this project is to develop new methods for manufacturing Type IV pressure vessels for hydrogen storage with the purpose of lowering the overall product cost through an innovative hybrid process of optimizing composite usage by combining traditional filament winding (FW) and advanced fiber placement (AFP) techniques. A numbers of vessels were manufactured in this project. The latest vessel design passed all the critical tests on the hybrid design per European Commission (EC) 79-2009 standard except the extreme temperature cycle test. The tests passed include burst test, cycle test, accelerated stress rupture test and drop test. It was discovered the location where AFP and FW overlap for load transfer could be weakened during hydraulic cycling at 85°C. To design a vessel that passed these tests, the in-house modeling software was updated to add capability to start and stop fiber layers to simulate the AFP process. The original in-house software was developed for filament winding only. Alternative fiber was also investigated in this project, but the added mass impacted the vessel cost negatively due to the lower performance from the alternative fiber. Overall the project was a success to show the hybrid design is a viable solution to reduce fiber usage, thus driving down the cost of fuel storage vessels. Based on DOE’s baseline vessel size of 147.3L and 91kg, the 129L vessel (scaled to DOE baseline) in this project shows a 32% composite savings and 20% cost savings when comparing Vessel 15 hybrid design and the Quantum

  19. States reducing solar's soft costs

    Energy Technology Data Exchange (ETDEWEB)

    Meehan, Chris

    2012-07-01

    In 2012 the costs of modules will drop below the balance of system costs or 'soft costs' of solar in the US. Federal policy that nationalizes permitting processes could reduce some of the soft costs, but is unlikely. That's why states like California, Colorado, Connecticut and Vermont passed own laws to reduce soft costs by speeding solar permitting and reducing fees. (orig.)

  20. Autonomous exoskeleton reduces metabolic cost of walking.

    Science.gov (United States)

    Mooney, Luke M; Rouse, Elliott J; Herr, Hugh M

    2014-01-01

    We developed an autonomous powered leg exoskeleton capable of providing large amounts of positive mechanical power to the wearer during powered plantarflexion phase of walking. The autonomous exoskeleton consisted of a winch actuator fasted to the shin which pulled on fiberglass struts attached to a boot. The fiberglass struts formed a rigid extension of the foot when the proximal end of the strut was pulled in forward by the winch actuator. This lightweight, geometric transmission allowed the electric winch actuator to efficiently produce biological levels of power at the ankle joint. The exoskeleton was powered and controlled by lithium polymer batteries and motor controller worn around the waist. Preliminary testing on two subjects walking at 1.4 m/s resulted in the exoskeleton reducing the metabolic cost of walking by 6-11% as compared to not wearing the device. The exoskeleton provided a peak mechanical power of over 180 W at each ankle (mean standard ± deviation) and an average positive mechanical power of 27 ± 1 W total to both ankles, while electrically using 75-89 W of electricity. The batteries (800 g) used in this experiment are estimated to be capable of providing this level of assistance for up to 7 km of walking.

  1. Manufacturing of Low Cost, Durable Membrane Electrode Assemblies Engineered for Rapid Conditioning

    Energy Technology Data Exchange (ETDEWEB)

    Busby, Colin [W. L. Gore & Associates Inc., Newark, DE (United States)

    2017-05-23

    Over the past 20 years significant progress in membrane-electrode assembly (MEA) technology development for polymer electrolyte fuel cells (PEMFCs) has resulted in the PEMFC technology approaching a commercial reality for transportation applications. However, there remain two primary technical challenges to be addressed in the MEA. First and foremost is meeting the automotive cost targets: Producing a fuel cell stack cost competitive with today’s internal combustion engine. In addition to the material cost, MEA (and other components) and stack assembly production methods must be amenable for use in low cost, high speed, automotive assembly line. One impediment to this latter goal is that stack components must currently go through a long and tedious conditioning procedure before they produce optimal power. This so-called “break-in” can take many hours, and can involve quite complex voltage, temperature and/or pressure steps. These break-in procedures must be simplified and the time required reduced if fuel cells are to become a viable automotive engine. The second challenge is to achieve the durability targets in real-world automotive duty cycle operations. Significant improvements in cost, break-in time, and durability for the key component of fuel cell stacks, MEAs were achieved in this project. Advanced modeling was used to guide design of the new MEA to maximize performance and durability. A new, innovative process and manufacturing approach utilizing direct in-line coating using scalable, cost-competitive, continuous high volume 3-layer rolled-good manufacturing processes was developed and validated by single cell and short stack testing. In addition, the direct coating methods employed were shown to reduce the cost for sacrificial films. Furthermore, Gore has demonstrated a 10 µm reinforced membrane that is used in the new low-cost process and can meet automotive power density and durability targets. Across a wide range of operating conditions, the

  2. Product costing guide for wood dimension and component manufacturers

    Science.gov (United States)

    Adrienn Andersch; Urs Buehlmann; Jeff Palmer; Janice K. Wiedenbeck; Steve. Lawser

    2014-01-01

    The North American hardwood dimension and components industry plays a critical role in the hardwood forest products industry as the industry is a user of high-value hardwood lumber. Customer expectations, global markets, and international competition, however, require hardwood dimension and components manufacturers to continuously improve their ability to manage their...

  3. Warranty optimisation based on the prediction of costs to the manufacturer using neural network model and Monte Carlo simulation

    Science.gov (United States)

    Stamenkovic, Dragan D.; Popovic, Vladimir M.

    2015-02-01

    Warranty is a powerful marketing tool, but it always involves additional costs to the manufacturer. In order to reduce these costs and make use of warranty's marketing potential, the manufacturer needs to master the techniques for warranty cost prediction according to the reliability characteristics of the product. In this paper a combination free replacement and pro rata warranty policy is analysed as warranty model for one type of light bulbs. Since operating conditions have a great impact on product reliability, they need to be considered in such analysis. A neural network model is used to predict light bulb reliability characteristics based on the data from the tests of light bulbs in various operating conditions. Compared with a linear regression model used in the literature for similar tasks, the neural network model proved to be a more accurate method for such prediction. Reliability parameters obtained in this way are later used in Monte Carlo simulation for the prediction of times to failure needed for warranty cost calculation. The results of the analysis make possible for the manufacturer to choose the optimal warranty policy based on expected product operating conditions. In such a way, the manufacturer can lower the costs and increase the profit.

  4. SOME IMPORTANT FACTORS AFFECTING EVOLUTION OF ACTIVITY BASED COSTING (ABC SYSTEM IN EGYPTIAN MANUFACTURING FIRMS

    Directory of Open Access Journals (Sweden)

    Karim MAMDOUH ABBAS

    2014-04-01

    Full Text Available The present investigation aims to determine the factors affecting evolution of Activity Based Costing (ABC system in Egyptian case. The study used the survey method to describe and analyze these factors in some Egyptian firms. The population of the study is Egyptian manufacturing firms. Accordingly, the number of received questionnaires was 392 (23 Egyptian manufacturing firms in the first half of 2013. Finally, the study stated some influencing factors for evolution this system (ABC in Egyptian manufacturing firms.

  5. Methods Reduce Cost, Enhance Quality of Nanotubes

    Science.gov (United States)

    2009-01-01

    For all the challenges posed by the microgravity conditions of space, weight is actually one of the more significant problems NASA faces in the development of the next generation of U.S. space vehicles. For the Agency s Constellation Program, engineers at NASA centers are designing and testing new vessels as safe, practical, and cost-effective means of space travel following the eventual retirement of the space shuttle. Program components like the Orion Crew Exploration Vehicle, intended to carry astronauts to the International Space Station and the Moon, must be designed to specific weight requirements to manage fuel consumption and match launch rocket capabilities; Orion s gross liftoff weight target is about 63,789 pounds. Future space vehicles will require even greater attention to lightweight construction to help conserve fuel for long-range missions to Mars and beyond. In order to reduce spacecraft weight without sacrificing structural integrity, NASA is pursuing the development of materials that promise to revolutionize not only spacecraft construction, but also a host of potential applications on Earth. Single-walled carbon nanotubes are one material of particular interest. These tubular, single-layer carbon molecules - 100,000 of them braided together would be no thicker than a human hair - display a range of remarkable characteristics. Possessing greater tensile strength than steel at a fraction of the weight, the nanotubes are efficient heat conductors with metallic or semiconductor electrical properties depending on their diameter and chirality (the pattern of each nanotube s hexagonal lattice structure). All of these properties make the nanotubes an appealing material for spacecraft construction, with the potential for nanotube composites to reduce spacecraft weight by 50 percent or more. The nanotubes may also feature in a number of other space exploration applications, including life support, energy storage, and sensor technologies. NASA s various

  6. Reducing DfM to practice: the lithography manufacturability assessor

    Science.gov (United States)

    Liebmann, Lars; Mansfield, Scott; Han, Geng; Culp, James; Hibbeler, Jason; Tsai, Roger

    2006-03-01

    The need for accurate quantification of all aspects of design for manufacturability using a mutually compatible set of quality-metrics and units-of-measure, is reiterated and experimentally verified. A methodology to quantify the lithography component of manufacturability is proposed and its feasibility demonstrated. Three stages of lithography manufacturability assessment are described: process window analysis on realistic integrated circuits following layout manipulations for resolution enhancement and the application of optical proximity correction, failure sensitivity analysis on simulated achievable dimensional bounds (a.k.a. variability bands), and yield risk analysis on iso-probability bands. The importance and feasibility of this technique is demonstrated by quantifying the lithography manufacturability impact of redundant contact insertion and Critical Area optimization in units that can be used to drive an overall layout optimization. The need for extensive experimental calibration and improved simulation accuracy is also highlighted.

  7. Smartfactory: challenges of open and low cost ICT in the small manufacturing industry

    CSIR Research Space (South Africa)

    Bosscha, P

    2006-02-27

    Full Text Available The neglected field of appropriate information and communications technologies for small companies in the manufacturing industry is addressed through the development of an architecture that integrates various open and low-cost technologies...

  8. IT/Automation Cost Reduction in Intel€ٳ Manufacturing Environment

    OpenAIRE

    Subirana, Brian

    2004-01-01

    Intel manufacturing relies heavily on IT and Factory Automation during the manufacturing processes. At Intel, everything from scheduling products on the floor and product delivery systems to statistical process control is done through automation systems. Shortly after an Intel meeting described in the case, a new position Computing Cost Reduction Manager - was created to lead a team within Factory Automation to drive cost reduction efforts which was a top priority for Intel in 2003. The compu...

  9. VIABILITY OF SOME APPLIED COST SYSTEMS IN MANUFACTURING FIRMS: EGYPT'S CASE

    Directory of Open Access Journals (Sweden)

    Karim Mamdouh ABBAS

    2015-04-01

    Full Text Available The present study aims to analyze viability of some applied cost systems. The population of the study is some Egyptian manufacturing firms. The number of received questionnaires was 385. The results indicated that , according to the application extent indicator, the currently cost systems in Egyptian manufacturing firms may be descendingly arranged as follows: Activity Based Costing (ABC system, Target Costing (TC system , Resource Consumption Accounting (RCA system, Activity Based Management (ABM ,Other systems, Theory of Constraints (TOC and Value Chain (VC analysis.

  10. Implementation of activity-based costing (ABC) to drive cost reduction efforts in a semiconductor manufacturing operation

    Science.gov (United States)

    Naguib, Hussein; Bol, Igor I.; Lora, J.; Chowdhry, R.

    1994-09-01

    This paper presents a case study on the implementation of ABC to calculate the cost per wafer and to drive cost reduction efforts for a new IC product line. The cost reduction activities were conducted through the efforts of 11 cross-functional teams which included members of the finance, purchasing, technology development, process engineering, equipment engineering, production control, and facility groups. The activities of these cross functional teams were coordinated by a cost council. It will be shown that these activities have resulted in a 57% reduction in the wafer manufacturing cost of the new product line. Factors contributed to successful implementation of an ABC management system are discussed.

  11. Costs Models in Design and Manufacturing of Sand Casting Products

    CERN Document Server

    Perry, Nicolas; Bernard, Alain

    2010-01-01

    In the early phases of the product life cycle, the costs controls became a major decision tool in the competitiveness of the companies due to the world competition. After defining the problems related to this control difficulties, we will present an approach using a concept of cost entity related to the design and realization activities of the product. We will try to apply this approach to the fields of the sand casting foundry. This work will highlight the enterprise modelling difficulties (limits of a global cost modelling) and some specifics limitations of the tool used for this development. Finally we will discuss on the limits of a generic approach.

  12. Cost-optimised cell manufacturing; Kostenoptimierte Batterie-Zellfertigung

    Energy Technology Data Exchange (ETDEWEB)

    Ruprecht, Ester [Karlsruher Institut fuer Technologie (KIT), Karlsruhe (Germany). Gruppe ' Produktionsforschung in der Elektromobilitaet' ; Kaiser, Joerg [Karlsruher Institut fuer Technologie (KIT), Eggenstein-Leopoldshafen (Germany). Project Competence E

    2013-05-15

    Where are the potentials of energy storage development? In production-technical and product-related approaches. There it may lead to a cost reduction for lithium-ion cells of approximately 35 %. At Karlsruhe Institute of Technology (KIT) the implementation of the production-technical and the product-related approaches is carried out by an interdisciplinary team that pursues an integrated product development approach. Parallel to the implementation of the approaches, costs are continuously monitored to be able to display the potential for cost reduction. (orig.)

  13. Manual for Reducing Educational Unit Costs in Latin American Countries.

    Science.gov (United States)

    Centro Multinacional de Investigacion Educativa, San Jose (Costa Rica).

    Designed for educational administrators, this manual provides suggestions for reducing educational unit costs in Latin America without reducing the quality of the education. Chapter one defines unit cost concepts and compares the costs of the Latin American countries. Chapter two deals with the different policies which could affect the principal…

  14. Manual for Reducing Educational Unit Costs in Latin American Countries.

    Science.gov (United States)

    Centro Multinacional de Investigacion Educativa, San Jose (Costa Rica).

    Designed for educational administrators, this manual provides suggestions for reducing educational unit costs in Latin America without reducing the quality of the education. Chapter one defines unit cost concepts and compares the costs of the Latin American countries. Chapter two deals with the different policies which could affect the principal…

  15. Autonomous Droop Scheme With Reduced Generation Cost

    DEFF Research Database (Denmark)

    Nutkani, Inam Ullah; Loh, Poh Chiang; Wang, Peng

    2014-01-01

    Droop schemes have traditionally been applied to the control of parallel synchronous generators in power systems. It has subsequently been brought over to the control of distributed generators (DGs) in microgrids with the same retained objective of proportional power sharing based on ratings....... This objective might, however, not suit microgrids well since DGs are usually of different types, unlike synchronous generators. Other factors like cost, efficiency, and emission penalty of each DG at different loading must be considered since they contribute directly to the total generation cost (TGC...... likely to be accepted by the industry. The reduction in TGC has been verified by experiment....

  16. ICAM (Integrated Computer-Aided Manufacturing) Manufacturing Cost/Design Guide. Volume 7. Technology Transfer Summary.

    Science.gov (United States)

    1984-09-01

    advanced composite structures for production. Conduct material and manufacturing trade-off studies on ATF advanced design, NASA composite wing, and...255-7371. D-17 .* . . . . . . .. . .. .. . . . . . - . , o , . . - .’. TTD4502 60000 12 Sept 1984 CC tE % > LL 00 o0h K; Cr A .’ TTD450260000 12... coatings on the internal "Top-of-the-Line" Manu- observing the effect of the surfaces of hollowf~acturing Technology Success proposed change. Potential

  17. PCS: a pallet costing system for wood pallet manufacturers (version 1.0 for Windows®)

    Science.gov (United States)

    A. Jefferson, Jr. Palmer; Cynthia D. West; Bruce G. Hansen; Marshall S. White; Hal L. Mitchell

    2002-01-01

    The Pallet Costing System (PCS) is a computer-based, Microsoft Windows® application that computes the total and per-unit cost of manufacturing an order of wood pallets. Information about the manufacturing facility, along with the pallet-order requirements provided by the customer, is used in determining production cost. The major cost factors addressed by PCS...

  18. Autonomous droop scheme with reduced generation cost

    DEFF Research Database (Denmark)

    Nutkani, Inam Ullah; Loh, Poh Chiang; Blaabjerg, Frede

    2013-01-01

    Droop scheme has been widely applied to the control of Distributed Generators (DGs) in microgrids for proportional power sharing based on their ratings. For standalone microgrid, where centralized management system is not viable, the proportional power sharing based droop might not suit well since...... DGs are usually of different types unlike synchronous generators. This paper presents an autonomous droop scheme that takes into consideration the operating cost, efficiency and emission penalty of each DG since all these factors directly or indirectly contributes to the Total Generation Cost (TGC......) of the overall microgrid. Comparing it with the traditional scheme, the proposed scheme has retained its simplicity, which certainly is a feature preferred by the industry. The overall performance of the proposed scheme has been verified through simulation and experiment....

  19. Low Cost and Energy Efficient Methods for the Manufacture of Semi-Solid (SSM) Feedstock

    Energy Technology Data Exchange (ETDEWEB)

    Diran Apelian; Qingyue Pan; Makhlouf Makhlouf

    2005-11-07

    The SSM Consortium (now ACRC) at WPI has been carrying out fundamental, pre-competitive research in SSM for several years. Current and past research (at WPI) has generated many results of fundamental and applied nature, which are available to the SSM community. These include materials characterization, yield stress effects, alloy development, rheological properties, process modeling/simulation, semi-solid slurry formation, etc. Alternative method to produce SSM slurries at lower processing costs and with reduced energy consumption is a critical need. The production of low cost SSM feedstock will certainly lead to a dramatic increase in the tonnage of castings produced by SSM, and will provide end users such as the transportation industry, with lighter, cheaper and high performance materials. In this program, the research team has addressed three critical issues in semi-solid processing. They are: (1) Development of low cost, reliable slurry-on-demand approaches for semi-solid processing; (2) Application of the novel permanent grain refining technology-SiBloy for the manufacture of high-quality SSM feedstock, and (3) Development of computational and modeling tools for semi-solid processing to enhance SSM process control. Salient results from these studies are summarized and detailed in our final technical report.

  20. Cost reduction and manufacture of the SunSine{reg_sign} AC module: Phase I Annual Report : 21 April 1998 -- 31 October 1999

    Energy Technology Data Exchange (ETDEWEB)

    Kern, E.; Kern, G.

    2000-03-06

    This report summarizes the progress made by Ascension Technology in Phase 1 of the cost reduction and manufacturing improvements of the SunSine{reg_sign} AC Module. This work, conducted under NREL subcontract, is a two-phase effort consisting of investigations into improving inverter packaging, soft switching, circuit optimization, design for manufacturing, manufacturing processes, and pilot production manufacturing. The objective of this subcontract is to significantly reduce the cost of the SunSine{reg_sign} inverter, enhance its performance, and streamline and expand the manufacturing process. During Phase 1, the soft-switching topology was designed, then refined to meet stringent cost and performance goals. This design resulted in improved performance, smaller overall footprint, and reduced costs. The aluminum inverter housing was redesigned, and the decision was made to conformal coat the circuit boards, which was verified through the HAST (Highly Accelerated Stress Testing) method. Potential international markets were identified, and the inverter is designed to be easily modified to meet the requirements of other countries. Significant cost reduction and performance improvements have been achieved in Phase I, and accomplishments during Phase I include: (1) SunSine{reg_sign} AC Module costs have been reduced enough to be able to reduce the suggested list price; (2) successful implementation of soft-switching; (3) power circuit-board size reduced 53{percent}; (4) power circuit-board component count reduced 34{percent}; (5) total inverter parts count reduced 49{percent}; (6) anticipated inverter manufacturing cost reduced 57{percent} on a $/Wp rating; (7) transformer efficiency improved 1.4{percent}; and (8) inverter efficiency improved 4.7{percent} to 91.0{percent} at 275 Wac.

  1. Cost Savings Analysis Guidelines for Manufacturing Technology Projects.

    Science.gov (United States)

    1985-06-28

    14 3.2.1 ’CHANGED COSTO SAMPLE PROJECT .................. .. 16 3.2.1.1 COST SAVINGS NARRATIVE ..................... 17 3.2.1.2 RECURRING COSTS...the Level II refurbishment techniques, develop additional Level III regrinding techniques, and produce a generic manual on bearing rework procedures...40 c L0 4) 10 4) ) 4-0 4 0C A 0~~ 0 10 4C C 4) I L.~1 0 f ) AU 1 .01 4S *~~C P;ir L 0I. 0 4) - 0 0IC C I-.C*12 IA Iii 0 0 0~~~ N b>v> *w .0 o a ab2 0

  2. Development and Manufacture of Cost Effective Composite Drill Pipe

    Energy Technology Data Exchange (ETDEWEB)

    James C. Leslie; James C. Leslie, II; Lee Truong; James T. Heard

    2006-09-29

    This technical report presents the engineering research, process development and data accomplishments that have transpired to date in support of the development of Cost Effective Composite Drill Pipe (CDP). The report presents progress made from October 1, 2005 through September 30, 2006 and contains the following discussions: Qualification Testing; Prototype Development and Testing of ''Smart Design'' Configuration; Field Test Demonstration; Development of Ultra-Short Radius Composite Drill Pipe (USR-CDP); and Development of Smart USR-CDP.

  3. DEVELOPMENT AND MANUFACTURE OF COST EFFECTIVE COMPOSITE DRILL PIPE

    Energy Technology Data Exchange (ETDEWEB)

    James C. Leslie; James C. Leslie II; Lee Truong; James T. Heard; Peter Manekas

    2005-03-18

    This technical report presents the engineering research, process development and data accomplishments that have transpired to date in support of the development of Cost Effective Composite Drill Pipe (CDP). The report presents progress made from October 1, 2003 through September 30, 2004 and contains the following discussions: (1) Direct Electrical Connection for Rotary Shoulder Tool Joints; (2) Conductors for inclusion in the pipe wall (ER/DW-CDP); (3) Qualify fibers from Zoltek; (4) Qualify resin from Bakelite; (5) First commercial order for SR-CDP from Integrated Directional Resources (SR-CDP); and (6) Preparation of papers for publication and conference presentations.

  4. Strategies Used by Adults to Reduce Their Prescription Drug Costs

    Science.gov (United States)

    ... Order from the National Technical Information Service NCHS Strategies Used by Adults to Reduce Their Prescription Drug ... Interview Survey, alternative therapies, medication Adults used several strategies to reduce prescription drug costs. Figure 1. Percentages ...

  5. DEVELOPMENT AND MANUFACTURE OF COST EFFECTIVE COMPOSITE DRILL PIPE

    Energy Technology Data Exchange (ETDEWEB)

    James C. Leslie; James C. Leslie II; Lee Truong; James T. Heard

    2003-03-30

    This technical report presents the engineering research and data accomplishments that have transpired to date in support of the development of Cost Effective Composite Drill Pipe (CDP). The report presents accomplishments made from October 1, 2002 through September 30, 2003. The following have been accomplished and are reported in detail herein: Metal-to-Composite Interface (MCI) redesign and testing; Successful demonstration of MCI connection for both SR and ER/DW CDP; Specifications for a 127mm (5 inch) ID by 152.4 mm (6 inch) OD composite drill pipe have been finalized for Extended Reach/Deep Water applications (ER/DW); Field testing of Short Radius CDP (SR); Sealing composite laminate to contain high pressure; Amendments; Amendment for ''Smart'' feature added to ER/DW development along with time and funding to complete battery of qualification tests with option for field demonstration; and Preparation of papers for publication and conference presentations.

  6. Using Innovative Methodologies From Technology and Manufacturing Companies to Reduce Heart Failure Readmissions.

    Science.gov (United States)

    Johnson, Amber E; Winner, Laura; Simmons, Tanya; Eid, Shaker M; Hody, Robert; Sampedro, Angel; Augustine, Sharon; Sylvester, Carol; Parakh, Kapil

    2016-05-01

    Heart failure (HF) patients have high 30-day readmission rates with high costs and poor quality of life. This study investigated the impact of a framework blending Lean Sigma, design thinking, and Lean Startup on 30-day all-cause readmissions among HF patients. This was a prospective study in an academic hospital in Baltimore, Maryland. Thirty-day all-cause readmission was assessed using the hospital's electronic medical record. The baseline readmission rate for HF was 28.4% in 2010 with 690 discharges. The framework was developed and interventions implemented in the second half of 2011. The impact of the interventions was evaluated through 2012. The rate declined to 18.9% among 703 discharges (P manufacturing companies can reduce 30-day readmissions in HF, demonstrating the potential of this innovations framework to improve chronic disease care.

  7. ICAM (Integrated Computer-Aided Manufacturing) Manufacturing Cost/Design Guide. Volume 6. Project Summary.

    Science.gov (United States)

    1985-01-01

    FIGURE 11. EXAMPLE OF CED FORM.AT FOR ALUMI;NUM, SKIN 3-11 ,. .. >. . 1 .. . . • , 0 0 20 30 40 50 FTR450260000 15 Jan 1985 356-TS/ A356 -T6 ALUMINUM ...of DICE Format for Sheet Metal Parts .. 3-10 11 Example of CED Format for Aluminum Skin. . . . .. 3-11 12 Example of CED Format for Aluminum ...Investment Castings ............. . . . . . 3-12 13 Example of CED Format for Material Cost of Aluminum Extrusions .... ............. ... 3-13 14 Example of

  8. Using Electromagnetic Algorithm for Total Costs of Sub-contractor Optimization in the Cellular Manufacturing Problem

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Shahriari

    2016-12-01

    Full Text Available In this paper, we present a non-linear binary programing for optimizing a specific cost in cellular manufacturing system in a controlled production condition. The system parameters are determined by the continuous distribution functions. The aim of the presented model is to optimize the total cost of imposed sub-contractors to the manufacturing system by determining how to allocate the machines and parts to each seller. In this system, DM could control the occupation level of each machine in the system. For solving the presented model, we used the electromagnetic meta-heuristic algorithm and Taguchi method for determining the optimal algorithm parameters.

  9. Towards Reduced Nickel-Cadmium Battery Cost for Micro Satellites

    OpenAIRE

    1994-01-01

    This paper presents the two Nickel-Cadmium technologies offered by Saft for satellites applications: the space-qualified VOS prismatic cells designed for long term LEO and GEO missions, and the VRE cylindrical cell devoted to launcher activities and to short life LEO missions for mini and micro satellites. It also details Saft's effort to minimize the cost for these cells - in strict compliance with customer's specification and without any changes to the existing product manufacturing process.

  10. Determining the total cost of reverse supply chain operations for original equipment manufacturers

    DEFF Research Database (Denmark)

    Larsen, Samuel Brüning; Jacobsen, Peter

    2014-01-01

    When original equipment manufacturers (OEM) examine whether or not to invest in a reverse supply chain (RSC), managers need insight into not only the cost savings and new revenue streams the RSC enables, but also the total cost of the RSC itself. Using case study research the study examines what...... cost parameters constitute the total cost (TC) of the RSC. The specific RSC that the study seeks the TC for consists of 1) end-product refurbishing, 2) component refurbishing, and 3) sales of used materials back to original suppliers or independent recyclers for materials recycling....

  11. Cost model relationships between textile manufacturing processes and design details for transport fuselage elements

    Science.gov (United States)

    Metschan, Stephen L.; Wilden, Kurtis S.; Sharpless, Garrett C.; Andelman, Rich M.

    1993-01-01

    Textile manufacturing processes offer potential cost and weight advantages over traditional composite materials and processes for transport fuselage elements. In the current study, design cost modeling relationships between textile processes and element design details were developed. Such relationships are expected to help future aircraft designers to make timely decisions on the effect of design details and overall configurations on textile fabrication costs. The fundamental advantage of a design cost model is to insure that the element design is cost effective for the intended process. Trade studies on the effects of processing parameters also help to optimize the manufacturing steps for a particular structural element. Two methods of analyzing design detail/process cost relationships developed for the design cost model were pursued in the current study. The first makes use of existing databases and alternative cost modeling methods (e.g. detailed estimating). The second compares design cost model predictions with data collected during the fabrication of seven foot circumferential frames for ATCAS crown test panels. The process used in this case involves 2D dry braiding and resin transfer molding of curved 'J' cross section frame members having design details characteristic of the baseline ATCAS crown design.

  12. ASPECTS OF OBSTACLES FOR APPLYING TARGET COSTING: A SURVEY OF MANUFACTURING FIRMS IN EGYPT

    Directory of Open Access Journals (Sweden)

    Petru STEFEA

    2014-04-01

    Full Text Available The present investigation aims to determine the aspects of obstacles for applying Target Costing(TC system in Egyptian case and the significant differences among effects of these obstacles . The study used the survey method to describe and analyze the obstacles in some Egyptian firms. The population of the study is Egyptian manufacturing firms. Accordingly, the number of received questionnaires was 388 (21 Egyptian manufacturing firms in 2013. Finally, the study found that there is a significant divergence among obstacles for applying Target Costing (TC system in Egyptian manufacturing firms (Internal and external.The external dimensions are the most influence of internal dimensions, where the weakness of the competition is the highest effect in the external dimensions case but resistance top management is the highest effect in external dimensions case.

  13. MORE COSTLY OR MORE PRODUCTIVE? MEASURING CHANGES IN COMPETITIVENESS IN MANUFACTURING ACROSS REGIONS IN CHINA

    NARCIS (Netherlands)

    Chen, Vivian W.; Wu, Harry X.; van Ark, Bart

    2009-01-01

    Using a newly constructed industry-by-region dataset based on China's two censuses, this paper examines the trend of average labor compensation (ALC), labor productivity (ALP) and unit labor cost (ULC) in 28 manufacturing industries across 29 provinces in China for 1995 and 2004. Findings show that

  14. Does Access to Finance Lower Firms’ Cost of Capital? Empirical Evidence from International Manufacturing Data

    NARCIS (Netherlands)

    Lashitew, Addisu A.

    2011-01-01

    Lack of access to finance is argued to be one of the most binding constraints for firm growth. There is, however, limited empirical evidence on the relationship between access to finance and the cost of capital. This paper uses international manufacturing data to analyze the effect of access to fina

  15. Does Access to Finance Lower Firms’ Cost of Capital? Empirical Evidence from International Manufacturing Data

    NARCIS (Netherlands)

    Lashitew, Addisu A.

    2011-01-01

    Lack of access to finance is argued to be one of the most binding constraints for firm growth. There is, however, limited empirical evidence on the relationship between access to finance and the cost of capital. This paper uses international manufacturing data to analyze the effect of access to fina

  16. MORE COSTLY OR MORE PRODUCTIVE? MEASURING CHANGES IN COMPETITIVENESS IN MANUFACTURING ACROSS REGIONS IN CHINA

    NARCIS (Netherlands)

    Chen, Vivian W.; Wu, Harry X.; van Ark, Bart

    2009-01-01

    Using a newly constructed industry-by-region dataset based on China's two censuses, this paper examines the trend of average labor compensation (ALC), labor productivity (ALP) and unit labor cost (ULC) in 28 manufacturing industries across 29 provinces in China for 1995 and 2004. Findings show that

  17. Technology alternatives towards low-cost and high-speed interconnect manufacturing

    NARCIS (Netherlands)

    Roozeboom, F.; Kniknie, B.; Lankhorst, A.M.; Winands, G.; Poodt, P.; Dingemans, G.; Keuning, W.; Kessels, W.M.M.; Bullema, J.E.; Bressers, P.M.M.C.; Oosterhuis, G.; Mueller, M.; Huis in 't Veld, Bert

    2012-01-01

    In this work we will review our recent work on novel alternative and disruptive technology concepts with industrial potential for cost-effective and high-speed interconnect manufacturing, in particular on the creation (drilling and filling) of advanced interconnects like TSVs. These technologies are

  18. Technology alternatives towards low-cost and high-speed interconnect manufacturing

    NARCIS (Netherlands)

    Roozeboom, F.; Kniknie, B.; Lankhorst, A.M.; Winands, G.; Poodt, P.; Dingemans, G.; Keuning, W.; Kessels, W.M.M.; Bullema, J.E.; Bressers, P.M.M.C.; Oosterhuis, G.; Mueller, M.; Huis in 't Veld, A.J.

    2012-01-01

    In this work we will review our recent work on novel alternative and disruptive technology concepts with industrial potential for cost-effective and high-speed interconnect manufacturing, in particular on the creation (drilling and filling) of advanced interconnects like TSVs. These technologies are

  19. Towards the next generation 23% efficient n-type cells with low cost manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Yelundur, Vijay [Suniva Inc., Norcross, GA (United States)

    2017-04-19

    Suniva, Inc., in collaboration with the University Center for Excellence in Photovoltaics (UCEP) at the Georgia Institute of Technology (GIT) proposed this comprehensive three year program to enable the development of an advanced high performance product that will help the US regain its competitive edge in PV. This project was designed to overcome cost and efficiency barriers through advances in PV science, technology innovation, low-cost manufacturing and full production of ~22.5% efficient n-type Si cells in Norcross, GA. At the heart of the project is the desire to complement the technology being developed concurrently under the Solarmat and ARPAe initiatives to develop a differentiated product superior in both performance and cost effectiveness to the competing alternatives available on the market, and push towards achieving SunShot objectives while ensuring a sustainable business model based on US manufacturing. A significant reduction of the costs in modules produced today will need to combine reductions in wafer costs, cell processing costs as well as module fabrication costs while delivering a product that is not only more efficient under test conditions but also increases the energy yield in outdoor operations. This project will result in a differentiated high performance product and technology that is consistent with sustaining PV manufacturing in the US for a longer term and further highlights the need for continued support for developing the next generation concepts that can keep US manufacturing thriving to support the growing demand for PV in the US and consistent with the US government’s mandates for energy independence.

  20. ACTIVITY-BASED COSTING DAN SIMULATED ANNEALING UNTUK PENCARIAN RUTE PADA FLEXIBLE MANUFACTURING SYSTEMS

    Directory of Open Access Journals (Sweden)

    Gregorius Satia Budhi

    2003-01-01

    Full Text Available Flexible Manufacturing System (FMS is a manufacturing system that is formed from several Numerical Controlled Machines combine with material handling system, so that different jobs can be worked by different machines sequences. FMS combine the high productivity and flexibility of Transfer Line and Job Shop manufacturing system. In this reasearch, Activity-Based Costing(ABC approach was used as the weight to search the operation route in the proper machine, so that the total production cost can be optimized. The search method that was used in this experiment is Simulated Annealling, a variant form Hill Climbing Search method. An ideal operation time to proses a part was used as the annealling schedule. From the empirical test, it could be proved that the use of ABC approach and Simulated Annealing to search the route (routing process can optimize the Total Production Cost. In the other hand, the use of ideal operation time to process a part as annealing schedule can control the processing time well. Abstract in Bahasa Indonesia : Flexible Manufacturing System (FMS adalah sistem manufaktur yang tersusun dari mesin-mesin Numerical Control (NC yang dikombinasi dengan Sistem Penanganan Material, sehingga job-job berbeda dikerjakan oleh mesin-mesin dengan alur yang berlainan. FMS menggabungkan produktifitas dan fleksibilitas yang tinggi dari Sistem Manufaktur Transfer Line dan Job Shop. Pada riset ini pendekatan Activity-Based Costing (ABC digunakan sebagai bobot / weight dalam pencarian rute operasi pada mesin yang tepat, untuk lebih mengoptimasi biaya produksi secara keseluruhan. Adapun metode Searching yang digunakan adalah Simulated Annealing yang merupakan varian dari metode searching Hill Climbing. Waktu operasi ideal untuk memproses sebuah part digunakan sebagai Annealing Schedulenya. Dari hasil pengujian empiris dapat dibuktikan bahwa penggunaan pendekatan ABC dan Simulated Annealing untuk proses pencarian rute (routing dapat lebih

  1. Strategies for reducing material costs through implementation of clinical guidelines.

    Science.gov (United States)

    Vollman, K; Sprung, P; Posa, S; Ladin, D; Kachhal, S K

    1998-01-01

    This paper presents a case study where the efforts to improve clinical guidelines resulted in significant savings in material costs through the standardization of the supplies and negotiation of contracts with the suppliers. It also presents an approach that is now being used to standardize material and reduce supply costs in other areas of the health system.

  2. 38 CFR 36.4251 - Loans to finance the purchase of manufactured homes and the cost of necessary site preparation.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Loans to finance the... Manufactured Home Lot Loans § 36.4251 Loans to finance the purchase of manufactured homes and the cost of necessary site preparation. (a) A loan to finance the purchase of a manufactured home may include funds...

  3. DEVELOPMENT OF LOW-COST MANUFACTURING PROCESSES FOR PLANAR, MULTILAYER SOLID OXIDE FUEL CELL ELEMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Scott Swartz; Matthew Seabaugh; William Dawson; Harlan Anderson; Tim Armstrong; Michael Cobb; Kirby Meacham; James Stephan; Russell Bennett; Bob Remick; Chuck Sishtla; Scott Barnett; John Lannutti

    2004-06-12

    This report summarizes the results of a four-year project, entitled, ''Low-Cost Manufacturing Of Multilayer Ceramic Fuel Cells'', jointly funded by the U.S. Department of Energy, the State of Ohio, and by project participants. The project was led by NexTech Materials, Ltd., with subcontracting support provided by University of Missouri-Rolla, Michael A. Cobb & Co., Advanced Materials Technologies, Inc., Edison Materials Technology Center, Gas Technology Institute, Northwestern University, and The Ohio State University. Oak Ridge National Laboratory, though not formally a subcontractor on the program, supported the effort with separate DOE funding. The objective of the program was to develop advanced manufacturing technologies for making solid oxide fuel cell components that are more economical and reliable for a variety of applications. The program was carried out in three phases. In the Phase I effort, several manufacturing approaches were considered and subjected to detailed assessments of manufacturability and development risk. Estimated manufacturing costs for 5-kW stacks were in the range of $139/kW to $179/kW. The risk assessment identified a number of technical issues that would need to be considered during development. Phase II development work focused on development of planar solid oxide fuel cell elements, using a number of ceramic manufacturing methods, including tape casting, colloidal-spray deposition, screen printing, spin-coating, and sintering. Several processes were successfully established for fabrication of anode-supported, thin-film electrolyte cells, with performance levels at or near the state-of-the-art. The work in Phase III involved scale-up of cell manufacturing methods, development of non-destructive evaluation methods, and comprehensive electrical and electrochemical testing of solid oxide fuel cell materials and components.

  4. Development of a Low-Cost Process for Manufacturing of Ti-Metal Matrix Composite by Roll-Diffusion Bonding

    Science.gov (United States)

    Testani, C.; Ferraro, F.

    2010-06-01

    Composite materials with titanium-alloy matrix are currently the class of material with the highest specific resistance at temperatures up to 800 °C. The main hurdle to their application is their final cost. Even if it is clear that the costs of constituent materials are decreasing due to volume production effects, the production processing costs remain high due to the batch production approach. Centro Sviluppo Materiali’s (CSM) efforts have focused on the manufacturing process in order to obtain an innovative solution to reduce the manufacturing costs with respect to the hot isostatic pressing (HIP) process that represents the standard production process for this class of materials. The new approach can allow a cost reduction of about 40%; this result was obtained by developing an experimental “diffusion bonding” plant for co-rolling at high temperature in a superplastic rolling regime, sheets of titanium alloy and monofilament silicon carbide fabrics. The experimental pilot plant was proposed for patent with RM2006A000261 in May 2006. This paper describes the manufacturing phases and process results. Moreover, has been shown that the diffusion in the solid state was obtained in a process window that was at least 100 times faster than that of HIP. High-temperature tensile tests were carried out on specimens machined from metallic matrix composite materials produced with the roll-diffusion bonding (RDB) process. The samples produced were also submitted to electrochemical dissolution tests of the metallic matrix in order to verify the geometric integrity of the fibers inside the matrix after the bonding phase. The results achieved as well as the process knowledge acquired with the CSM pilot plant are the base for further development of industrial application of the titanium roll-diffusion bonding.

  5. Cost Reduction Key Drivers Within a Small Batch Aerospace Manufacturing Line

    OpenAIRE

    Delamare, Adrien

    2016-01-01

    This report details my work at the endpoint of the internship I spent within the Composite Manufacturing Unit of Airbus Defence & Space in Les Mureaux, France. It is as well the conclusion of the master’s program in aerospace engineering that I attended at KTH Royal Institute of Technology, Sweden.This document gives an overview of the cost reduction key drivers within a small batch aerospace manufacturing line. Some of the suggested leads developed in the paper have been set up in the pa...

  6. Strategic research on the sustainable development cost of manufacturing industry under the background of carbon allowance and trade policy

    Science.gov (United States)

    Ma, Zhongmin; Cheng, Mengting; Wang, Mei

    2017-08-01

    The important subjects of energy consumption and carbon emission are manufacturing enterprises, with the deepening of international cooperation, and the implementation of carbon limit and trade policy, costs of manufacturing industry will rise sharply. How can the manufacturing industry survive in this reform, and it has to be a problem that the managers of the manufacturing industry need to solve. This paper analyses sustainable development cost connotation and value basis on the basis of sustainable development concept, discusses the influence of carbon allowance and trade policy for cost strategy of manufacturing industry, thinks that manufacturing industry should highlight social responsibility and realize maximization of social value, implement cost strategy the sustainable development, and pointed out the implementation way.

  7. Optical Metrology for CIGS Solar Cell Manufacturing and its Cost Implications

    Science.gov (United States)

    Sunkoju, Sravan Kumar

    Solar energy is a promising source of renewable energy which can meet the demand for clean energy in near future with advances in research in the field of photovoltaics and cost reduction by commercialization. Availability of a non-contact, in-line, real time robust process control strategies can greatly aid in reducing the gap between cell and module efficiencies, thereby leading to cost-effective large-scale manufacturing of high efficiency CIGS solar cells. In order to achieve proper process monitoring and control for the deposition of the functional layers of CuIn1-xGaxSe 2 (CIGS) based thin film solar cell, optical techniques such as spectroscopic reflectometry and polarimetry are advantageous because they can be set up in an unobtrusive manner in the manufacturing line, and collect data in-line and in-situ. The use of these techniques requires accurate optical models that correctly represent the properties of the layers being deposited. In this study, Spectroscopic ellipsometry (SE) has been applied for the characterization of each individual stage of CIGS layers deposited using the 3-stage co-evaporation process along with the other functional layers. Dielectric functions have been determined for the energy range from 0.7 eV to 5.1 eV. Critical-point line-shape analysis was used in this study to determine the critical point energies of the CIGS based layers. To control the compositional and thickness uniformity of all the functional layers during the fabrication of CIGS solar cells over large areas, multilayer photovoltaics (PV) stack optical models were developed with the help of extracted dielectric functions. In this study, mapping capability of RC2 spectroscopic ellipsometer was used to map all the functional layer thicknesses of a CIGS solar cell in order to probe the spatial non-uniformities that can affect the performance of a cell. The optical functions for each of the stages of CIGS 3-stage deposition process along with buffer layer and transparent

  8. Analyzing Cost Parameters Affecting Map Reduce Application Performance

    Directory of Open Access Journals (Sweden)

    N.K. Seera

    2016-08-01

    Full Text Available Recently, big data analysis has become an imperative task for many big companies. Map-Reduce, an emerging distributed computing paradigm, is known as a promising architecture for big data analytics on commodity hardware. Map-Reduce, and its open source implementation Hadoop, have been extensively accepted by several companies due to their salient features such as scalability, elasticity, fault-tolerance and flexibility to handle big data. However, these benefits entail a considerable performance sacrifice. The performance of a Map-Reduce application depends on various factors including the size of the input data set, cluster resource settings etc. A clear understanding of the factors that affect Map-Reduce application performance and the cost associated with those factors is required. In this paper, we study different performance parameters and an existing Cost Optimizer that computes the cost of Map-Reduce job execution. The cost based optimizer also considers various configuration parameters available in Hadoop that affect performance of these programs. This paper is an attempt to analyze the Map-Reduce application performance and identifying the key factors affecting the cost and performance of executing Map-Reduce applications.

  9. Lean Manufacturing - A Powerfull Tool for Reducing Waste During the Processes

    Directory of Open Access Journals (Sweden)

    Mihai Apreutesei

    2010-01-01

    Full Text Available Lean manufacturing provides a new management approach for many small and medium size manufacturers, especially older firms organized and managed under traditional push systems. Improvement results can be dramatic in terms of quality, cycle times, and customer responsiveness. Lean manufacturing is more than a set of tools and techniques and has been widely adopted by many production companies. Lean manufacturing is a culture in which all employees continuously look for ways to improve processes. In the present article are presented the Lean Manufacturing tools, like kaizen, Kanban, poka-yoke witch a company can use to reduce the waste(muda during a production process. The paper contains also, the most common seven types of waste from production and some examples from our daily activity.

  10. Normative price for a manufactured product: the SAMICS methodology. Volume II. Analysis. JPL publication 78-98. [Solar Array Manufacturing Industry Costing Standards

    Energy Technology Data Exchange (ETDEWEB)

    Chamberlain, R.G.

    1979-01-15

    The Solar Array Manufacturing Industry Costing Standards (SAMICS) provide standard formats, data, assumptions, and procedures for determining the price a hypothetical solar array manufacturer would have to be able to obtain in the market to realize a specified after-tax rate of return on equity for a specified level of production. This document presents the methodology and its theoretical background. It is contended that the model is sufficiently general to be used in any production-line manufacturing environment. Implementation of this methodology by the Solar Array Manufacturing Industry Simulation computer program (SAMIS III, Release 1) is discussed.

  11. Status and opportunities associated with product costing strategies in wood component manufacturing

    Science.gov (United States)

    Adrienn Andersch; Urs Buehlmann; Jan Wiedenbeck; Steve. Lawser

    2013-01-01

    Product costing systems are critically important for businesses because they help reduce costs, price products at competitive prices, and enable strategic decisionmaking. This article reports the results of a survey designed to collect information about practices used by the North American hardwood dimension and components industry to calculate the cost of their...

  12. Manufacturing of high performance, low cost dual mirror lamp reflector modules

    Science.gov (United States)

    Shen, Li

    The Lamp Reflector Module (LRM) is a key component in every micro display projection system, which has played a dominant role in the large-screen display market today. The goal of this research is to (1) improve the Dual Mirror prototype's light output performance, (2) investigate the underlying principles of its slow output deterioration so as to help develop effective and efficient LRM thermal management for maximized lifetime performance, and (3) improve/enable low cost mass LRM manufacturing for the projection display market. The first part of this research addresses the prototype's low output problem. More sophisticated 3D Optical Ray Tracing (ORT) models were generated to provide the output prediction depending on the arc gap, system collection etendue, etc. It was concluded that upgrading the manufacturing processes, particularly the reflector shape, surface and cold mirror coating, could effectively improve the output performance. Additionally, these theoretical models are shown to be used to design a LRM with 16% output gain for the consumer Rear Projection display market. The second part of this research focuses on the issue of lifetime performance. The electrode, arc attachment and envelope evolution were monitored by camera systems. The upgraded ORT models confirmed the arc length insensitivity property of the Dual Mirror LRM being one of the major reasons for its longer native lifetime. The third part of this research focuses on issues related to the entire LRM manufacturing. A series of quality control tools were developed to help implement manufacturing process optimization. LRMs made with the upgraded manufacturing processes showed about 25% output gain over the previous prototypes. Based on the imaging property of the Dual Mirror LRM, a lower cost lamp reflector alignment method, called cold alignment, was developed. In this method, the etendue efficiency is maintained and a slower degrading and more stable lifetime output performance are achieved

  13. (Dysfunctionality of accounting cost systems in manufacturing companies of Tuzla canton

    Directory of Open Access Journals (Sweden)

    Sado Puškarević

    2014-12-01

    Full Text Available This paper shows the results of the conducted primary survey on functionality of cost systems in manufacturing companies of Tuzla Canton (hereinafter “TC”. This paper assesses their adequacy to the needs of these companies: the present needs, and the ones that will be brought by the changes in the environment. These systems have to be up-to-date, as they influence the process of cost management, which is the key factor of companies’ adaptation to the conditions of a modern market. Cost management, which is based on the information of a cost system, enables the company to take the adequate stand towards customers on markets and toward their competition. Also, the quality cost information is a precondition for effective and efficient allocation of limited resources in a transitional period of society development. Therefore, only quality designed cost system in transitional economy will enable recovery, and then, growth and development of a company. This emphasizes the importance of research of the stated issues for transitional countries. The research results should also help to persuade the management about the need to modernize the operation organization, primarily the accounting function, mainly in the part of cost system organization. The determined defects, as well as deviances in relation to current needs for information about costs, are guidelines for an adequate process of redesigning cost systems in companies of transitional economy.

  14. Energy conserved and costs saved by small and medium-size manufacturers, 1988--1989

    Energy Technology Data Exchange (ETDEWEB)

    Kirsch, F.W.

    1991-05-01

    Energy Analysis and Diagnostic Centers (EADCs) provided energy-conserving and cost saving assistance in 339 small and medium-size manufacturing plants nationwide during 1988-89. This report presents the results of what was recommended to those manufacturers, the record of what was implemented by them, and an analysis of the financial rewards gained by them. It also includes an accounting of the financial returns to the federal government, derived from taxes upon the cost savings, or incremental income, of the manufacturers who implement the EADCs` recommendations. EADCs collect implementation data within a year of the energy audit, and for these results that time period extended through 1990. The EADCs are located at accredited engineering departments of universities and staffed by faculty and students. At present there are 18 EADCs serving manufacturers in 37 states; of these, two were established as a result of the 1989 competition, and five more were chosen competitively in 1990. Most of the results in this report were generated by 11 EADCs (named in the Appendix); two others withdrew voluntarily after completing only 10 energy audits during 1988-89. Primary responsibility for selecting, training, evaluating, and managing the EADCs belongs to the Industrial Technology and Energy Management (ITEM) division of University City Science Center (UCSC). The Department of Energy`s Office of Industrial Technologies sponsors the EADC program through an agreement with UCSC.

  15. MapReduce Based Parallel Bayesian Network for Manufacturing Quality Control

    Science.gov (United States)

    Zheng, Mao-Kuan; Ming, Xin-Guo; Zhang, Xian-Yu; Li, Guo-Ming

    2017-09-01

    Increasing complexity of industrial products and manufacturing processes have challenged conventional statistics based quality management approaches in the circumstances of dynamic production. A Bayesian network and big data analytics integrated approach for manufacturing process quality analysis and control is proposed. Based on Hadoop distributed architecture and MapReduce parallel computing model, big volume and variety quality related data generated during the manufacturing process could be dealt with. Artificial intelligent algorithms, including Bayesian network learning, classification and reasoning, are embedded into the Reduce process. Relying on the ability of the Bayesian network in dealing with dynamic and uncertain problem and the parallel computing power of MapReduce, Bayesian network of impact factors on quality are built based on prior probability distribution and modified with posterior probability distribution. A case study on hull segment manufacturing precision management for ship and offshore platform building shows that computing speed accelerates almost directly proportionally to the increase of computing nodes. It is also proved that the proposed model is feasible for locating and reasoning of root causes, forecasting of manufacturing outcome, and intelligent decision for precision problem solving. The integration of bigdata analytics and BN method offers a whole new perspective in manufacturing quality control.

  16. Affordable Design: A Methodolgy to Implement Process-Based Manufacturing Cost into the Traditional Performance-Focused Multidisciplinary Design Optimization

    Science.gov (United States)

    Bao, Han P.; Samareh, J. A.

    2000-01-01

    The primary objective of this paper is to demonstrate the use of process-based manufacturing and assembly cost models in a traditional performance-focused multidisciplinary design and optimization process. The use of automated cost-performance analysis is an enabling technology that could bring realistic processbased manufacturing and assembly cost into multidisciplinary design and optimization. In this paper, we present a new methodology for incorporating process costing into a standard multidisciplinary design optimization process. Material, manufacturing processes, and assembly processes costs then could be used as the objective function for the optimization method. A case study involving forty-six different configurations of a simple wing is presented, indicating that a design based on performance criteria alone may not necessarily be the most affordable as far as manufacturing and assembly cost is concerned.

  17. Broadcasting photonic lab on a chip concept through a low cost manufacturing approach.

    Science.gov (United States)

    Rodríguez-Ruiz, Isaac; Teychené, Sébastien; Van Pham, Nhat; Radajewski, Dimitri; Lamadie, Fabrice; Llobera, Andreu; Charton, Sophie

    2017-08-01

    A low cost fabrication process for photonic lab on a chip systems is here proposed. For the implementation of the masters suitable for cast molding fabrication, an inexpensive dry film photoresist, patternable using standard laboratory equipment, is benchmarked against standardized SU-8 masters obtained using UV lithography and systems manufacture in clean room facilities. Results show adequate system fabrication and a comparable performance of the photonic structures for absorbance/extinction measurements. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Productivity improvement through cost reduction of a manufacturing line of electrical harnesses

    OpenAIRE

    Moreno Perea, Karlos Gerardo; Universidad Autónoma de Querétaro; Reyes López, Octavio; Universidad Virtual del Estado de Guanajuato

    2015-01-01

    Nowadays due to the great variety of automotive suppliers, the companies have adopted a cost reduction system which allow them to remain competitive for the main automotive OEM´s (Original Equipment Manufacturers). In this particular case, the studied company established as a mid-term objective the improvement of the productivity in one of its production lines that produced automotive electrical harnesses of the Clutch Jumper family during two work shifts, using thirty five direct operators p...

  19. Development of hybrid lifecycle cost estimating tool (HLCET) for manufacturing influenced design tradeoff

    Science.gov (United States)

    Sirirojvisuth, Apinut

    In complex aerospace system design, making an effective design decision requires multidisciplinary knowledge from both product and process perspectives. Integrating manufacturing considerations into the design process is most valuable during the early design stages since designers have more freedom to integrate new ideas when changes are relatively inexpensive in terms of time and effort. Several metrics related to manufacturability are cost, time, and manufacturing readiness level (MRL). Yet, there is a lack of structured methodology that quantifies how changes in the design decisions impact these metrics. As a result, a new set of integrated cost analysis tools are proposed in this study to quantify the impacts. Equally important is the capability to integrate this new cost tool into the existing design methodologies without sacrificing agility and flexibility required during the early design phases. To demonstrate the applicability of this concept, a ModelCenter environment is used to develop software architecture that represents Integrated Product and Process Development (IPPD) methodology used in several aerospace systems designs. The environment seamlessly integrates product and process analysis tools and makes effective transition from one design phase to the other while retaining knowledge gained a priori. Then, an advanced cost estimating tool called Hybrid Lifecycle Cost Estimating Tool (HLCET), a hybrid combination of weight-, process-, and activity-based estimating techniques, is integrated with the design framework. A new weight-based lifecycle cost model is created based on Tailored Cost Model (TCM) equations [3]. This lifecycle cost tool estimates the program cost based on vehicle component weights and programmatic assumptions. Additional high fidelity cost tools like process-based and activity-based cost analysis methods can be used to modify the baseline TCM result as more knowledge is accumulated over design iterations. Therefore, with this

  20. ACTIVITY-BASED COSTING IN THE MANUFACTURING SECTOR: A MANAGERIAL INSTRUMENT FOR DECISION-MAKING

    Directory of Open Access Journals (Sweden)

    Ioana D. BUFAN

    2014-04-01

    Full Text Available The aim of this paper is to emphasize the importance of using the activity-based costing (management system in the manufacturing sector. The utility of the ABC (ABM system concerns decisions taken at a strategic and operational level. In our country, few managers understand the need for such a system and many Romanian companies use only a traditional costing system or don’t use one at all. The paper also includes a case study which is a small example of using the ABC method in a Romanian manufacturing company. The study shows that the ABC/ABM system helps managers to properly manage indirect costs (by activities and understand the profitability of products, distribution channels and customers. Therefore, it offers a powerful instrument for decision-making. Although ABC is a new system of cost calculation that is absolutely necessary, in most cases the ABC method must be implemented in addition to the traditional costing systems, which are essential for the purposes of management accounting.

  1. ACTIVITY-BASED COSTING IN THE MANUFACTURING SECTOR: A MANAGERIAL INSTRUMENT FOR DECISION-MAKING

    Directory of Open Access Journals (Sweden)

    Ioana D. BUFAN

    2014-04-01

    Full Text Available The aim of this paper is to emphasize the importance of using the activity-based costing (management system in the manufacturing sector. The utility of the ABC (ABM system concerns decisions taken at a strategic and operational level. In our country, few managers understand the need for such a system and many Romanian companies use only a traditional costing system or don’t use one at all. The paper also includes a case study which is a small example of using the ABC method in a Romanian manufacturing company. The study shows that the ABC/ABM system helps managers to properly manage indirect costs (by activities and understand the profitability of products, distribution channels and customers. Therefore, it offers a powerful instrument for decision-making. Although ABC is a new system of cost calculation that is absolutely necessary, in most cases the ABC method must be implemented in addition to the traditional costing systems, which are essential for the purposes of management accounting.

  2. Cost Estimate in Virtual Manufacturing System%虚拟制造环境下成本评估技术

    Institute of Scientific and Technical Information of China (English)

    石旭东; 付宜利; 刘原强; 马玉林; 姬舒平

    2001-01-01

    介绍了通过历史成本数据矩阵,寻求最小成本路径,估算最小成本和确定最优工艺路径的方法,为虚拟制造和产品设计提供了有效的决策工具。%Virtual manufacturing is a new technology, and manufacturability evaluation is o ne of the key technologies in virtual manufacturing system Cost estimate is an important part in manufacturability evaluation A new method is presented to e stimate cost by select the minimal manufacturing cost process sequence with the historical cost matrix.

  3. Research on Cost Index of Working Procedure in Manufacturing Process Based on Activity-Based Costing%基于作业成本法的制造过程工序成本指标研究

    Institute of Scientific and Technical Information of China (English)

    解德凤; 王慧; 付秀丽; 聂金宁

    2011-01-01

    In order to control the quality cost of manufacturing process effectively, it proposes the method of cost index of working procedure based on activity - based costing. Taking the manufacturing process of transmission shaft in heavy duty machine tools enterprise as an example, it uses activity- based costing theory to distribute the loss cost of manufacturing process among the working procedures, formulates the maximum allowable quality loss index of working procedure. The results show that working procedure cost index can play an important part in improving the qualified rate of product, reducing the mass loss and quality cost of manufacturing process.%为给制造过程质量成本控制提供有效依据,提出了基于作业成本法的工序成本指标研究方法.以某重型机床制造企业一批传动轴的加工过程为例,采用作业成本法理论,将制造过程产生的损失费用分配到各工序,制定各工序最大允许质量损失指标.结果表明,工序成本指标研究对降低制造过程质量损失率、提高产品合格率、降低质量成本具有一定的指导作用.

  4. Entry Deterrence Through Fixed Cost-Reducing R&D

    OpenAIRE

    Gamal Atallah

    2006-01-01

    The paper explores the role of R&D investments reducing fixed production costs in entry deterrence. An incumbent monopolist performs R&D to reduce its fixed production costs. There is a potential entrant, which can also perform R&D for the same purpose. There are bidirectional technological spillovers between the incumbent and the potential entrant. It is shown that deterrence, which takes the form of underinvestment in R&D by the incumbent, is more likely when the spillover from the incumben...

  5. Optimizing Ice Thermal Storage to Reduce Energy Cost

    Science.gov (United States)

    Hall, Christopher L.

    Energy cost for buildings is an issue of concern for owners across the U.S. The bigger the building, the greater the concern. A part of this is due to the energy required to cool the building and the way in which charges are set when paying for energy consumed during different times of the day. This study will prove that designing ice thermal storage properly will minimize energy cost in buildings. The effectiveness of ice thermal storage as a means to reduce energy costs lies within transferring the time of most energy consumption from on-peak to off-peak periods. Multiple variables go into the equation of finding the optimal use of ice thermal storage and they are all judged with the final objective of minimizing monthly energy costs. This research discusses the optimal design of ice thermal storage and its impact on energy consumption, energy demand, and the total energy cost. A tool for optimal design of ice thermal storage is developed, considering variables such as chiller and ice storage sizes and charging and discharge times. The simulations take place in a four-story building and investigate the potential of Ice Thermal Storage as a resource in reducing and minimizing energy cost for cooling. The simulations test the effectiveness of Ice Thermal Storage implemented into the four-story building in ten locations across the United States.

  6. Cost-Benefit Analysis and Assessment of Ergonomic Interventions Effects: Case Study Boiler and Equipment Engineering and Manufacturing Company

    Directory of Open Access Journals (Sweden)

    Iraj Mohammad faam

    2015-12-01

    Full Text Available Background & Objectives: In Economic and competitive world today,cost-benefit analysis is one of the most important parameters for any intervention.The purpose of thisstudy was cost-benefit analysis of ergonomic interventions effects in Boiler and Equipment Engineering and Manufacturing Company. Methods:At first all workstations of the company assessed using QEC. Thenthose earned more than 70% in QEC assessed by OWAS. By analyzing the results of these two methods, the “Haarp welding” workstation selected as the critical one. After presentation of possible solutions in specialized committee, the final solution selected and cost-benefit analysis done by CyberManS tool. Finally after implementing the intervention workstation reassessed. Findings:The results of the survey showed that the final score of assessment using QEC, OWAS and NASA-TLX before the intervention was 84.7%, 3 and 75.4, respectively and after the intervention was 47.5%, 1 and 42.7 that witnesses a significant reduction in all three methods of assessment. Also the result of cost-benefit analysis by CyberManS showed that by spending 110 million rials after 1.5 years the investment returned and profitability initiated. Conclusion:In addition to reducing the risk of musculoskeletal disorders, ergonomic interventions have financial benefits by increasing the productivity and production, reducing the compensation and the lost work days can also cause financial benefits.

  7. Cost benchmarking of railway projects in Europe – can it help to reduce costs?

    DEFF Research Database (Denmark)

    Trabo, Inara; Landex, Alex; Nielsen, Otto Anker

    This paper highlights the methodology of construction cost benchmarking of railway projects in the EU and its preliminary results. Benchmarking helps project managers learn from others, improve particular project areas, and reduce project costs. For railway projects, benchmarking is essential...... for the comparison of unit costs for major cost drivers (e.g. tunnels, bridges, etc.). This methodology was applied to the case study described in this paper, the first high-speed railway project in Denmark, “The New Line Copenhagen-Ringsted”. The aim was to avoid cost overruns and even reduce final budget outcomes...... by looking for the best practices in the construction and implementation of other high-speed lines in Europe and learning from their experience. The paper presents benchmarking from nine railway projects that are comparable with the Copenhagen-Ringsted project. The results of this comparison provide...

  8. Wellness Programs: Preventive Medicine to Reduce Health Care Costs.

    Science.gov (United States)

    Martini, Gilbert R., Jr.

    1991-01-01

    A wellness program is a formalized approach to preventive health care that can positively affect employee lifestyle and reduce future health-care costs. Describes programs for health education, smoking cessation, early detection, employee assistance, and fitness, citing industry success figures. (eight references) (MLF)

  9. Rightsizing HVAC Systems to Reduce Capital Costs and Save Energy

    Science.gov (United States)

    Sebesta, James

    2010-01-01

    Nearly every institution is faced with the situation of having to reduce the cost of a construction project from time to time through a process generally referred to as "value engineering." Just the mention of those words, however, gives rise to all types of connotations, thoughts, and memories (usually negative) for those in the facilities…

  10. Automotive Lithium-ion Cell Manufacturing: Regional Cost Structures and Supply Chain Considerations

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Donald [Clean Energy Manufacturing Analysis Center, Godlen, CO (United States); Elgqvist, Emma [Clean Energy Manufacturing Analysis Center, Godlen, CO (United States); Santhanagopalan, Shriram [Clean Energy Manufacturing Analysis Center, Godlen, CO (United States)

    2016-04-08

    Manufacturing capacity for lithium-ion batteries (LIBs)--which power many consumer electronics and are increasingly used to power electric vehicles--is heavily concentrated in east Asia. Currently, China, Japan, and Korea collectively host 88% of all LIB cell and 79% of automotive LIB cell manufacturing capacity. Mature supply chains and strong cumulative production experience suggest that most LIB cell production will remain concentrated in Asia. However, other regions--including North America--could be competitive in the growing automotive LIB cell market under certain conditions. To illuminate the factors that drive regional competitiveness in automotive LIB cell production, this study models cell manufacturing cost and minimum sustainable price, and examines development of LIB supply chains and current LIB market conditions. Modeled costs are for large format, 20-Ah stacked pouch cells with lithium-nickel-manganese-cobalt-oxide (NMC) cathodes and graphite anodes suitable for automotive application. Production volume is assumed to be at commercial scale, 600 MWh per year.

  11. Cost Study for Manufacturing of Solid Oxide Fuel Cell Power Systems

    Energy Technology Data Exchange (ETDEWEB)

    Weimar, Mark R.; Chick, Lawrence A.; Gotthold, David W.; Whyatt, Greg A.

    2013-09-30

    Solid oxide fuel cell (SOFC) power systems can be designed to produce electricity from fossil fuels at extremely high net efficiencies, approaching 70%. However, in order to penetrate commercial markets to an extent that significantly impacts world fuel consumption, their cost will need to be competitive with alternative generating systems, such as gas turbines. This report discusses a cost model developed at PNNL to estimate the manufacturing cost of SOFC power systems sized for ground-based distributed generation. The power system design was developed at PNNL in a study on the feasibility of using SOFC power systems on more electric aircraft to replace the main engine-mounted electrical generators [Whyatt and Chick, 2012]. We chose to study that design because the projected efficiency was high (70%) and the generating capacity was suitable for ground-based distributed generation (270 kW).

  12. Cost savings associated with improving appropriate and reducing inappropriate preventive care: cost-consequences analysis

    Directory of Open Access Journals (Sweden)

    Baskerville Neill

    2005-03-01

    Full Text Available Abstract Background Outreach facilitation has been proven successful in improving the adoption of clinical preventive care guidelines in primary care practice. The net costs and savings of delivering such an intensive intervention need to be understood. We wanted to estimate the proportion of a facilitation intervention cost that is offset and the potential for savings by reducing inappropriate screening tests and increasing appropriate screening tests in 22 intervention primary care practices affecting a population of 90,283 patients. Methods A cost-consequences analysis of one successful outreach facilitation intervention was done, taking into account the estimated cost savings to the health system of reducing five inappropriate tests and increasing seven appropriate tests. Multiple data sources were used to calculate costs and cost savings to the government. The cost of the intervention and costs of performing appropriate testing were calculated. Costs averted were calculated by multiplying the number of tests not performed as a result of the intervention. Further downstream cost savings were determined by calculating the direct costs associated with the number of false positive test follow-ups avoided. Treatment costs averted as a result of increasing appropriate testing were similarly calculated. Results The total cost of the intervention over 12 months was $238,388 and the cost of increasing the delivery of appropriate care was $192,912 for a total cost of $431,300. The savings from reduction in inappropriate testing were $148,568 and from avoiding treatment costs as a result of appropriate testing were $455,464 for a total savings of $604,032. On a yearly basis the net cost saving to the government is $191,733 per year (2003 $Can equating to $3,687 per physician or $63,911 per facilitator, an estimated return on intervention investment and delivery of appropriate preventive care of 40%. Conclusion Outreach facilitation is more expensive

  13. Reduced prosthetic stiffness lowers the metabolic cost of running for athletes with bilateral transtibial amputations.

    Science.gov (United States)

    Beck, Owen N; Taboga, Paolo; Grabowski, Alena Marie

    2017-01-19

    Inspired by the spring-like action of biological legs, running-specific prostheses are designed to enable athletes with lower-limb amputations to run. Yet, manufacturer recommendations for prosthetic stiffness and height may not optimize running performance. Therefore, we investigated the effects of using different prosthetic configurations on the metabolic cost and biomechanics of running. Five athletes with bilateral transtibial amputations each performed fifteen trials on a force-measuring treadmill at 2.5 or 3.0 m/s. Athletes ran using each of three different prosthetic models (Freedom Catapult FX6, Össur Flex-Run, and Ottobock 1E90 Sprinter) with five combinations of stiffness categories (manufacturer recommended and ± 1) and heights (International Paralympic Committee's maximum competition height and ± 2 cm) while we measured metabolic rates and ground reaction forces. Overall, prosthetic stiffness (fixed effect (β)=0.036; p=0.008) but not height (p≥0.089) affected the net metabolic cost of transport; less stiff prostheses reduced metabolic cost. While controlling for prosthetic stiffness (kN/m), using the Flex-Run (β=-0.139; p=0.044) and 1E90 Sprinter prostheses (β=-0.176; p=0.009) reduced net metabolic costs by 4.3% to 4.9% compared to using the Catapult prostheses, respectively. The metabolic cost of running improved when athletes used prosthetic configurations that decreased peak horizontal braking ground reaction forces (β=2.786; p=0.001), stride frequencies (β=0.911; p<0.001), and leg stiffness values (β=0.053; p=0.009). Remarkably, athletes did not maintain overall leg stiffness across prosthetic stiffness conditions. Rather, the in-series prosthetic stiffness governed overall leg stiffness. The metabolic cost of running in athletes with bilateral transtibial amputations is influenced by prosthetic model and stiffness, but not height.

  14. Design and high-volume manufacture of low-cost molded IR aspheres for personal thermal imaging devices

    Science.gov (United States)

    Zelazny, A. L.; Walsh, K. F.; Deegan, J. P.; Bundschuh, B.; Patton, E. K.

    2015-05-01

    The demand for infrared optical elements, particularly those made of chalcogenide materials, is rapidly increasing as thermal imaging becomes affordable to the consumer. The use of these materials in conjunction with established lens manufacturing techniques presents unique challenges relative to the cost sensitive nature of this new market. We explore the process from design to manufacture, and discuss the technical challenges involved. Additionally, facets of the development process including manufacturing logistics, packaging, supply chain management, and qualification are discussed.

  15. Yalın Üretim Ortamına Uygun Maliyet Sistemi Seçimi(Selection of Costing System Appropriate for Lean Manufacturing Environment

    Directory of Open Access Journals (Sweden)

    Funda ÖZÇELİK

    2013-01-01

    Full Text Available To be successful in global competition, the number of firms adopted lean manufacturing systems are increasing every day. Traditional cost management systems is insufficient to produce the information needed for businesses adopting lean manufacturing system. Value stream costing system, appropriate for lean manufacturing enterprises’s value stream organization, better serves the purpose of lean enterprises. In this study value stream costing introduced and selection of costing system for lean manufacturing environments will be done.

  16. Cost-effectiveness of pharmacotherapy to reduce obesity.

    Directory of Open Access Journals (Sweden)

    J Lennert Veerman

    Full Text Available AIMS: Obesity causes a high disease burden in Australia and across the world. We aimed to analyse the cost-effectiveness of weight reduction with pharmacotherapy in Australia, and to assess its potential to reduce the disease burden due to excess body weight. METHODS: We constructed a multi-state life-table based Markov model in Excel in which body weight influences the incidence of stroke, ischemic heart disease, hypertensive heart disease, diabetes mellitus, osteoarthritis, post-menopausal breast cancer, colon cancer, endometrial cancer and kidney cancer. We use data on effectiveness identified from PubMed searches, on mortality from Australian Bureau of Statistics, on disease costs from the Australian Institute of Health and Welfare, and on drug costs from the Department of Health and Ageing. We evaluate 1-year pharmacological interventions with sibutramine and orlistat targeting obese Australian adults free of obesity-related disease. We use a lifetime horizon for costs and health outcomes and a health sector perspective for costs. Incremental Cost-Effectiveness Ratios (ICERs below A$50 000 per Disability Adjusted Life Year (DALY averted are considered good value for money. RESULTS: The ICERs are A$130 000/DALY (95% uncertainty interval [UI] 93 000-180 000 for sibutramine and A$230 000/DALY (170 000-340 000 for orlistat. The interventions reduce the body weight-related disease burden at the population level by 0.2% and 0.1%, respectively. Modest weight loss during the interventions, rapid post-intervention weight regain and low adherence limit the health benefits. CONCLUSIONS: Treatment with sibutramine or orlistat is not cost-effective from an Australian health sector perspective and has a negligible impact on the total body weight-related disease burden.

  17. Cost-effectiveness of pharmacotherapy to reduce obesity.

    Science.gov (United States)

    Veerman, J Lennert; Barendregt, Jan J; Forster, Megan; Vos, Theo

    2011-01-01

    Obesity causes a high disease burden in Australia and across the world. We aimed to analyse the cost-effectiveness of weight reduction with pharmacotherapy in Australia, and to assess its potential to reduce the disease burden due to excess body weight. We constructed a multi-state life-table based Markov model in Excel in which body weight influences the incidence of stroke, ischemic heart disease, hypertensive heart disease, diabetes mellitus, osteoarthritis, post-menopausal breast cancer, colon cancer, endometrial cancer and kidney cancer. We use data on effectiveness identified from PubMed searches, on mortality from Australian Bureau of Statistics, on disease costs from the Australian Institute of Health and Welfare, and on drug costs from the Department of Health and Ageing. We evaluate 1-year pharmacological interventions with sibutramine and orlistat targeting obese Australian adults free of obesity-related disease. We use a lifetime horizon for costs and health outcomes and a health sector perspective for costs. Incremental Cost-Effectiveness Ratios (ICERs) below A$50 000 per Disability Adjusted Life Year (DALY) averted are considered good value for money. The ICERs are A$130 000/DALY (95% uncertainty interval [UI] 93 000-180 000) for sibutramine and A$230 000/DALY (170 000-340 000) for orlistat. The interventions reduce the body weight-related disease burden at the population level by 0.2% and 0.1%, respectively. Modest weight loss during the interventions, rapid post-intervention weight regain and low adherence limit the health benefits. Treatment with sibutramine or orlistat is not cost-effective from an Australian health sector perspective and has a negligible impact on the total body weight-related disease burden.

  18. Reducing Reforestation Costs in Lebanon: Adaptive Field Trials

    Directory of Open Access Journals (Sweden)

    Garabet (Garo Haroutunian

    2017-05-01

    Full Text Available Lebanon’s Ministry of Environment initiated a project in 2009 to determine low-cost reforestation techniques for stone pine (Pinus pinea and Lebanon cedar (Cedrus libani for large-scale land rehabilitation activities in the arid Middle East. Irrigation (several techniques vs. no water, planting (8- to 18-month-old seedlings, seeding, and soil preparation methods were evaluated in three sets of adaptive management field trials. The aim was to reduce reforestation costs while still achieving sufficient regeneration. A key result for management was that non-irrigated seed planting of stone pine and possibly of Lebanon cedar showed promise for cost-effective reforestation and could be competitive with seedlings, given correct seed source and planting conditions. Stone pine seeds collected from nearby mother trees and planted without irrigation on sandy soil showed 35% survival for <600 USD/ha; seedlings planted without irrigation cost about 2500 USD/ha and achieved 50–70% survival (costs based on 800 seedlings/ha. Water supplements increased establishment costs over 2 years without concomitant improvements to survival. Future studies should evaluate how soil texture and soil preparation interact with other factors to affect seed germination and survival for each species.

  19. Small Habitat Commonality Reduces Cost for Human Mars Missions

    Science.gov (United States)

    Griffin, Brand N.; Lepsch, Roger; Martin, John; Howard, Robert; Rucker, Michelle; Zapata, Edgar; McCleskey, Carey; Howe, Scott; Mary, Natalie; Nerren, Philip (Inventor)

    2015-01-01

    Most view the Apollo Program as expensive. It was. But, a human mission to Mars will be orders of magnitude more difficult and costly. Recently, NASA's Evolvable Mars Campaign (EMC) mapped out a step-wise approach for exploring Mars and the Mars-moon system. It is early in the planning process but because approximately 80% of the total life cycle cost is committed during preliminary design, there is an effort to emphasize cost reduction methods up front. Amongst the options, commonality across small habitat elements shows promise for consolidating the high bow-wave costs of Design, Development, Test and Evaluation (DDT&E) while still accommodating each end-item's functionality. In addition to DDT&E, there are other cost and operations benefits to commonality such as reduced logistics, simplified infrastructure integration and with inter-operability, improved safety and simplified training. These benefits are not without a cost. Some habitats are sub-optimized giving up unique attributes for the benefit of the overall architecture and because the first item sets the course for those to follow, rapidly developing technology may be excluded. The small habitats within the EMC include the pressurized crew cabins for the ascent vehicle,

  20. Reducing operating costs while protecting safety and the environment

    Energy Technology Data Exchange (ETDEWEB)

    Lund, R. [Transocean Drilling ASA, (Norway)

    1996-12-31

    The paper deals with the change process by reducing the operating costs in the petroleum industry while protecting safety and the environment. The author`s intention is to examine some of these cost reduction initiatives and see if they have affected the HSE (Health, Safety and Environment) parameters and subsequently how HSE has been managed during the change process. The examination will be from a contractor`s point of view. Topics are: organisational change; safety, environment and change; reduction of profit margins; changing contract strategy; restructuring of the drilling industry; technological development; environment

  1. DETERMINING ENERGY SAVINGS IN BUILDINGS USING THE REDUCING COSTS METHOD

    Directory of Open Access Journals (Sweden)

    STAN IVAN F.E.

    2015-03-01

    Full Text Available The paper is structured in four parts. The first part presents the importance of thermal insulation for buildings energy economy and some insulation properties. In the second part of the paper it is described the reducing cost method to determine the energy savings. The third part of the paper includes an analysis and a comparison for an exterior wall provided with different thicknesses of insulation layer in order to determine the average savings cost. The last part presents conclusions and discussion.

  2. Advanced Materials and Manufacturing for Low-Cost, High-Performance Liquid Rocket Combustion Chambers

    Science.gov (United States)

    Williams, Brian E.; Arrieta, Victor M.

    2013-01-01

    A document describes the low-cost manufacturing of C103 niobium alloy combustion chambers, and the use of a high-temperature, oxidation-resistant coating that is superior to the standard silicide coating. The manufacturing process involved low-temperature spray deposition of C103 on removable plastic mandrels produced by rapid prototyping. Thin, vapor-deposited platinum-indium coatings were shown to substantially improve oxidation resistance relative to the standard silicide coating. Development of different low-cost plastic thrust chamber mandrel materials and prototyping processes (selective laser sintering and stereolithography) yielded mandrels with good dimensional accuracy (within a couple of mils) for this stage of development. The feasibility of using the kinetic metallization cold-spray process for fabrication of free-standing C1O3 thrusters on removable plastic mandrels was also demonstrated. The ambient and elevated temperature mechanical properties of the material were shown to be reasonably good relative to conventionally processed C103, but the greatest potential benefit is that coldsprayed chambers require minimal post-process machining, resulting in substantially lower machining and material costs. The platinum-iridium coating was shown to provide greatly increased oxidation resistance over the silicide when evaluated through oxyacetylene torch testing to as high as 300 F (= 150 C). The iridium component minimizes reaction with the niobium alloy chamber at high temperatures, and provides the high-temperature oxidation resistance needed at the throat.

  3. Technical cost modelling for a novel semi-solid metal (SSM) casting processes for automotive component manufacturing

    CSIR Research Space (South Africa)

    Tlale, NS

    2008-09-01

    Full Text Available for the successful implementation of the manufacturing process (excludes auxiliary automation equipment such as robotics, forklifts, external PLCs, etc.). This variable is represented by RAux and determines the fraction of the total costs for all the auxiliary...

  4. Manufacturing Cost Analysis of Novel Steel/Concrete Composite Vessel for Stationary Storage of High-Pressure Hydrogen

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Zhili [ORNL; Zhang, Wei [ORNL; Wang, Jy-An John [ORNL; Ren, Fei [ORNL

    2012-09-01

    A novel, low-cost, high-pressure, steel/concrete composite vessel (SCCV) technology for stationary storage of compressed gaseous hydrogen (CGH2) is currently under development at Oak Ridge National Laboratory (ORNL) sponsored by DOE s Fuel Cell Technologies (FCT) Program. The SCCV technology uses commodity materials including structural steels and concretes for achieving cost, durability and safety requirements. In particular, the hydrogen embrittlement of high-strength low-alloy steels, a major safety and durability issue for current industry-standard pressure vessel technology, is mitigated through the use of a unique layered steel shell structure. This report presents the cost analysis results of the novel SCCV technology. A high-fidelity cost analysis tool is developed, based on a detailed, bottom-up approach which takes into account the material and labor costs involved in each of the vessel manufacturing steps. A thorough cost study is performed to understand the SCCV cost as a function of the key vessel design parameters, including hydrogen pressure, vessel dimensions, and load-carrying ratio. The major conclusions include: The SCCV technology can meet the technical/cost targets set forth by DOE s FCT Program for FY2015 and FY2020 for all three pressure levels (i.e., 160, 430 and 860 bar) relevant to the hydrogen production and delivery infrastructure. Further vessel cost reduction can benefit from the development of advanced vessel fabrication technologies such as the highly automated friction stir welding (FSW). The ORNL-patented multi-layer, multi-pass FSW can not only reduce the amount of labor needed for assembling and welding the layered steel vessel, but also make it possible to use even higher strength steels for further cost reductions and improvement of vessel structural integrity. It is noted the cost analysis results demonstrate the significant cost advantage attainable by the SCCV technology for different pressure levels when compared to the

  5. Role of the pharmacist in reducing healthcare costs: current insights

    Directory of Open Access Journals (Sweden)

    Dalton K

    2017-01-01

    Full Text Available Kieran Dalton, Stephen Byrne Pharmaceutical Care Research Group, School of Pharmacy, University College Cork, Cork, Ireland Abstract: Global healthcare expenditure is escalating at an unsustainable rate. Money spent on medicines and managing medication-related problems continues to grow. The high prevalence of medication errors and inappropriate prescribing is a major issue within healthcare systems, and can often contribute to adverse drug events, many of which are preventable. As a result, there is a huge opportunity for pharmacists to have a significant impact on reducing healthcare costs, as they have the expertise to detect, resolve, and prevent medication errors and medication-related problems. The development of clinical pharmacy practice in recent decades has resulted in an increased number of pharmacists working in clinically advanced roles worldwide. Pharmacist-provided services and clinical interventions have been shown to reduce the risk of potential adverse drug events and improve patient outcomes, and the majority of published studies show that these pharmacist activities are cost-effective or have a good cost:benefit ratio. This review demonstrates that pharmacists can contribute to substantial healthcare savings across a variety of settings. However, there is a paucity of evidence in the literature highlighting the specific aspects of pharmacists’ work which are the most effective and cost-effective. Future high-quality economic evaluations with robust methodologies and study design are required to investigate what pharmacist services have significant clinical benefits to patients and substantiate the greatest cost savings for healthcare budgets. Keywords: pharmacoeconomics, pharmaceutical care, clinical pharmacy, cost-effectiveness, economic evaluation

  6. Reducing electrocoagulation harvesting costs for practical microalgal biodiesel production.

    Science.gov (United States)

    Dassey, Adam J; Theegala, Chandra S

    2014-01-01

    Electrocoagulation has shown potential to be a primary microalgae harvesting technique for biodiesel production. However, methods to reduce energy and electrode costs are still necessary for practical application. Electrocoagulation tests were conducted on Nannochloris sp. and Dunaliella sp. using perforated aluminium and iron electrodes under various charge densities. Aluminium electrodes were shown to be more efficient than iron electrodes when harvesting both algal species. Despite the lower harvesting efficiency, however, the iron electrodes were more energy and cost efficient. Operational costs of less than $0.03/L oil were achieved when harvesting Nannochloris sp. with iron electrodes at 35% harvest efficiency, whereas aluminium electrodes cost $0.75/L oil with 42% harvesting efficiency. Increasing the harvesting efficiencies for both aluminium and iron electrodes also increased the overall cost per litre of oil, therefore lower harvesting efficiencies with lower energy inputs was recommended. Also, increasing the culturing salinity to 2 ppt sodium chloride for freshwater Nannochloris sp. was determined practical to improve the electrocoagulation energy efficiency despite a 25% reduction in cell growth.

  7. Smart Manufacturing.

    Science.gov (United States)

    Davis, Jim; Edgar, Thomas; Graybill, Robert; Korambath, Prakashan; Schott, Brian; Swink, Denise; Wang, Jianwu; Wetzel, Jim

    2015-01-01

    Historic manufacturing enterprises based on vertically optimized companies, practices, market share, and competitiveness are giving way to enterprises that are responsive across an entire value chain to demand dynamic markets and customized product value adds; increased expectations for environmental sustainability, reduced energy usage, and zero incidents; and faster technology and product adoption. Agile innovation and manufacturing combined with radically increased productivity become engines for competitiveness and reinvestment, not simply for decreased cost. A focus on agility, productivity, energy, and environmental sustainability produces opportunities that are far beyond reducing market volatility. Agility directly impacts innovation, time-to-market, and faster, broader exploration of the trade space. These changes, the forces driving them, and new network-based information technologies offering unprecedented insights and analysis are motivating the advent of smart manufacturing and new information technology infrastructure for manufacturing.

  8. Additive Manufacturing for Cost Efficient Production of Compact Ceramic Heat Exchangers and Recuperators

    Energy Technology Data Exchange (ETDEWEB)

    Shulman, Holly [Ceralink Incorporated, Troy, NY (United States); Ross, Nicole [Ceralink Incorporated, Troy, NY (United States)

    2015-10-30

    An additive manufacture technique known as laminated object manufacturing (LOM) was used to fabricate compact ceramic heat exchanger prototypes. LOM uses precision CO2 laser cutting of ceramic green tapes, which are then precision stacked to build a 3D object with fine internal features. Modeling was used to develop prototype designs and predict the thermal response, stress, and efficiency in the ceramic heat exchangers. Build testing and materials analyses were used to provide feedback for the design selection. During this development process, laminated object manufacturing protocols were established. This included laser optimization, strategies for fine feature integrity, lamination fluid control, green handling, and firing profile. Three full size prototypes were fabricated using two different designs. One prototype was selected for performance testing. During testing, cross talk leakage prevented the application of a high pressure differential, however, the prototype was successful at withstanding the high temperature operating conditions (1300 °F). In addition, analysis showed that the bulk of the part did not have cracks or leakage issues. This led to the development of a module method for next generation LOM heat exchangers. A scale-up cost analysis showed that given a purpose built LOM system, these ceramic heat exchangers would be affordable for the applications.

  9. Low-cost small scale parabolic trough collector design for manufacturing and deployment in Africa

    Science.gov (United States)

    Orosz, Matthew; Mathaha, Paul; Tsiu, Anadola; Taele, B. M.; Mabea, Lengeta; Ntee, Marcel; Khakanyo, Makoanyane; Teker, Tamer; Stephens, Jordan; Mueller, Amy

    2016-05-01

    Concentrating Solar Power is expanding its deployment on the African subcontinent, highlighting the importance of efforts to indigenize manufacturing of this technology to increase local content and therefore local economic benefits of these projects. In this study a design for manufacturing (DFM) exercise was conducted to create a locally produced parabolic trough collector (the G4 PTC). All parts were sourced or fabricated at a production facility in Lesotho, and several examples of the design were prototyped and tested with collaborators in the Government of Lesotho's Appropriate Technology Services division and the National University of Lesotho. Optical and thermal performance was simulated and experimentally validated, and pedagogical pre-commercial versions of the PTC have been distributed to higher education partners in Lesotho and Europe. The cost to produce the PTC is 180 USD/m2 for a locally manufactured heat collection element (HCE) capable of sustaining 250C operation at ~65% efficiency. A version with an imported evacuated HCE can operate at 300°C with 70% efficiency. Economically relevant applications for this locally produced PTC include industrial process heat and distributed generation scenarios where cogeneration is required.

  10. III-Vs at Scale: A PV Manufacturing Cost Analysis of the Thin Film Vapor-Liquid-Solid Growth Mode

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, Maxwell; Horowitz, Kelsey; Woodhouse, Michael; Battaglia, Corsin; Kapadia, Rehan; Javey, Ali

    2016-06-01

    The authors present a manufacturing cost analysis for producing thin-film indium phosphide modules by combining a novel thin-film vapor-liquid-solid (TF-VLS) growth process with a standard monolithic module platform. The example cell structure is ITO/n-TiO2/p-InP/Mo. For a benchmark scenario of 12% efficient modules, the module cost is estimated to be $0.66/W(DC) and the module cost is calculated to be around $0.36/W(DC) at a long-term potential efficiency of 24%. The manufacturing cost for the TF-VLS growth portion is estimated to be ~$23/m2, a significant reduction compared with traditional metalorganic chemical vapor deposition. The analysis here suggests the TF-VLS growth mode could enable lower-cost, high-efficiency III-V photovoltaics compared with manufacturing methods used today and open up possibilities for other optoelectronic applications as well.

  11. Next generation grinding spindle for cost-effective manufacture of advanced ceramic components

    Energy Technology Data Exchange (ETDEWEB)

    Kovach, J.A.; Laurich, M.A.

    2000-01-01

    Finish grinding of advanced structural ceramics has generally been considered an extremely slow and costly process. Recently, however, results from the High-Speed, Low-Damage (HSLD) program have clearly demonstrated that numerous finish-process performance benefits can be realized by grinding silicon nitride at high wheel speeds. A new, single-step, roughing-process capable of producing high-quality silicon nitride parts at high material removal rates while dramatically reducing finishing costs has been developed.

  12. Predictive models reduce talent development costs in female gymnastics.

    Science.gov (United States)

    Pion, Johan; Hohmann, Andreas; Liu, Tianbiao; Lenoir, Matthieu; Segers, Veerle

    2017-04-01

    This retrospective study focuses on the comparison of different predictive models based on the results of a talent identification test battery for female gymnasts. We studied to what extent these models have the potential to optimise selection procedures, and at the same time reduce talent development costs in female artistic gymnastics. The dropout rate of 243 female elite gymnasts was investigated, 5 years past talent selection, using linear (discriminant analysis) and non-linear predictive models (Kohonen feature maps and multilayer perceptron). The coaches classified 51.9% of the participants correct. Discriminant analysis improved the correct classification to 71.6% while the non-linear technique of Kohonen feature maps reached 73.7% correctness. Application of the multilayer perceptron even classified 79.8% of the gymnasts correctly. The combination of different predictive models for talent selection can avoid deselection of high-potential female gymnasts. The selection procedure based upon the different statistical analyses results in decrease of 33.3% of cost because the pool of selected athletes can be reduced to 92 instead of 138 gymnasts (as selected by the coaches). Reduction of the costs allows the limited resources to be fully invested in the high-potential athletes.

  13. Does a renewable fuel standard for biofuels reduce climate costs?

    Energy Technology Data Exchange (ETDEWEB)

    Greaker, Mads; Hoel, Michael; Rosendahl, Knut Einar

    2012-07-01

    Recent contributions have questioned whether biofuels policies actually lead to emissions reductions, and thus lower climate costs. In this paper we make two contributions to the literature. First, we study the market effects of a renewable fuel standard. Opposed to most previous studies we model the supply of fossil fuels taking into account that fossil fuels is a non-renewable resource. Second, we model emissions from land use change explicitly when we evaluate the climate effects of the renewable fuel standard. We find that extraction of fossil fuels most likely will decline initially as a consequence of the standard. Thus, if emissions from biofuels are sufficiently low, the standard will have beneficial climate effects. Furthermore, we find that the standard tends to reduce total fuel (i.e., oil plus biofuels) consumption initially. Hence, even if emissions from biofuels are substantial, climate costs may be reduced. Finally, if only a subset of countries introduce a renewable fuel standard, there will be carbon leakage to the rest of the world. However, climate costs may decline as global extraction of fossil fuels is postponed.(Author)

  14. Mobile Web Browsing Based On Content Preserving With Reduced Cost

    Directory of Open Access Journals (Sweden)

    Dr.N.Saravanaselvam

    2015-01-01

    Full Text Available Internet has played a drastic change in today’s life. Especially, web browsing has become more exclusive in compact devices. This tempts the people to migrate their innovations & skills into an unimaginable world. With these things in mind, it is necessary for us to concentrate more on the techniques that how the web data’s are accessed and accounted. Developed countries use a widely popular technique called Flat- rate pricing, which is solely independent on data usage. But whereas, developing countries are still behind the concept of “pay as you use”, which leads to high usage bills.With an effort to resolve the problem of high usage bills, we propose a cost effective technique, which reduces the data consumption in web mobile browsing. It reduces the usage bills in the mechanism of usage-based pricing. The key idea of our approach is to leverage the data plan of the user to compute a cost quota for each web request and a network middle-box to automatically adapt any web page to the cost quota. Here we use a simple but effective content adaption technique that highly decides which image or data best fits the mobile display with low cost and high quality resolution. It also emphasis on the trendy technique,” The Data Mining “which mines the requested & required data. The mined data’s are filtered based on the content adaption technique and fit into the display effectively. Interesting and noticeable feature in this concept is that only important web contents requested by the user are exhibited. A feedback process involves in this concept to retrieve the required data alone and also to improve the best fit resolution. With this proposed system web mobile browsing becomes cheaper & contributes an enormous logic for the future project in the field of Mobile browsing.

  15. Reducing Wildlife Damage with Cost-Effective Management Programmes.

    Directory of Open Access Journals (Sweden)

    Cheryl R Krull

    Full Text Available Limiting the impact of wildlife damage in a cost effective manner requires an understanding of how control inputs change the occurrence of damage through their effect on animal density. Despite this, there are few studies linking wildlife management (control, with changes in animal abundance and prevailing levels of wildlife damage. We use the impact and management of wild pigs as a case study to demonstrate this linkage. Ground disturbance by wild pigs has become a conservation issue of global concern because of its potential effects on successional changes in vegetation structure and composition, habitat for other species, and functional soil properties. In this study, we used a 3-year pig control programme (ground hunting undertaken in a temperate rainforest area of northern New Zealand to evaluate effects on pig abundance, and patterns and rates of ground disturbance and ground disturbance recovery and the cost effectiveness of differing control strategies. Control reduced pig densities by over a third of the estimated carrying capacity, but more than halved average prevailing ground disturbance. Rates of new ground disturbance accelerated with increasing pig density, while rates of ground disturbance recovery were not related to prevailing pig density. Stochastic simulation models based on the measured relationships between control, pig density and rate of ground disturbance and recovery indicated that control could reduce ground disturbance substantially. However, the rate at which prevailing ground disturbance was reduced diminished rapidly as more intense, and hence expensive, pig control regimes were simulated. The model produced in this study provides a framework that links conservation of indigenous ecological communities to control inputs through the reduction of wildlife damage and suggests that managers should consider carefully the marginal cost of higher investment in wildlife damage control, relative to its marginal conservation

  16. Reducing Wildlife Damage with Cost-Effective Management Programmes.

    Science.gov (United States)

    Krull, Cheryl R; Stanley, Margaret C; Burns, Bruce R; Choquenot, David; Etherington, Thomas R

    2016-01-01

    Limiting the impact of wildlife damage in a cost effective manner requires an understanding of how control inputs change the occurrence of damage through their effect on animal density. Despite this, there are few studies linking wildlife management (control), with changes in animal abundance and prevailing levels of wildlife damage. We use the impact and management of wild pigs as a case study to demonstrate this linkage. Ground disturbance by wild pigs has become a conservation issue of global concern because of its potential effects on successional changes in vegetation structure and composition, habitat for other species, and functional soil properties. In this study, we used a 3-year pig control programme (ground hunting) undertaken in a temperate rainforest area of northern New Zealand to evaluate effects on pig abundance, and patterns and rates of ground disturbance and ground disturbance recovery and the cost effectiveness of differing control strategies. Control reduced pig densities by over a third of the estimated carrying capacity, but more than halved average prevailing ground disturbance. Rates of new ground disturbance accelerated with increasing pig density, while rates of ground disturbance recovery were not related to prevailing pig density. Stochastic simulation models based on the measured relationships between control, pig density and rate of ground disturbance and recovery indicated that control could reduce ground disturbance substantially. However, the rate at which prevailing ground disturbance was reduced diminished rapidly as more intense, and hence expensive, pig control regimes were simulated. The model produced in this study provides a framework that links conservation of indigenous ecological communities to control inputs through the reduction of wildlife damage and suggests that managers should consider carefully the marginal cost of higher investment in wildlife damage control, relative to its marginal conservation return.

  17. Feasibility Analysis of Sustainability-Based Measures to Reduce VOC Emissions in Office Partition Manufacturing

    Directory of Open Access Journals (Sweden)

    Marc A. Rosen

    2010-02-01

    Full Text Available A feasibility analysis is reported of reduction opportunities for volatile organic compound (VOC emissions in manufacturing office furniture partitions, aimed at contributing to efforts to improve the sustainability of the process. A pollution prevention methodology is utilized. The purpose is to provide practical options for VOC emissions reductions during the manufacturing of office furniture partitions, but the concepts can be generally applied to the wood furniture industry. Baseline VOC emissions for a typical plant are estimated using a mass balance approach. The feasibility analysis expands on a preliminary screening to identify viable pollution prevention options using realistic criteria and weightings, and is based on technical, environmental and economic considerations. The measures deemed feasible include the implementation of several best management practices, ceasing the painting of non-visible parts, switching to hot melt backwrapping glue, application of solvent recycling and modification of the mechanical clip attachment. Implementation, measurement and control plans are discussed for the measures considered feasible, which can enhance the sustainability of the manufacturing of office furniture partitions. Reducing VOC emissions using the measures identified can, in conjunction with other measures, improve the sustainability of the manufacturing process.

  18. Low cost method for manufacturing a data acquisition system with USB connectivity

    Science.gov (United States)

    Niculescu, V.; Dobre, R. A.; Popovici, E.

    2016-06-01

    In the process of designing and manufacturing an electronic system the digital oscilloscope plays an essential role but it also represents one of the most expensive equipment present on the typical workbench. In order to make electronic design more accessible to students and hobbyists, an affordable data acquisition system was imagined. The paper extensively presents the development and testing of a low cost, medium speed, data acquisition system which can be used in a wide range of electronic measurement and debugging applications, assuring also great portability due to the small physical dimensions. Each hardware functional block and is thoroughly described, highlighting the challenges that occurred as well as the solutions to overcome them. The entire system was successfully manufactured using high quality components to assure increased reliability, and high frequency PCB materials and techniques were preferred. The measured values determined based on test signals were compared to the ones obtained using a digital oscilloscope available on the market and differences less than 1% were observed.

  19. Final Scientific/Technical Report: Low Cost, Structurally Advanced Novel Electrode and Cell Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Woodford, William [24M Technologies, Inc., Cambridge, MA (United States)

    2017-01-10

    This document is the final technical report from 24M Technologies on the project titled: Low Cost, Structurally Advanced Novel Electrode and Cell Manufacturing. All of the program milestones and deliverables were completed during the performance of the award. Specific accomplishments are 1) 24M demonstrated the processability and electrochemical performance of semi-solid electrodes with active volume contents increased by 10% relative to the program baseline; 2) electrode-level metrics, quality, and yield were demonstrated at an 80 cm2 electrode footprint; 3) these electrodes were integrated into cells with consistent capacities and impedances, including cells delivered to Argonne National Laboratory for independent testing; 4) those processes were scaled to a large-format (> 260 cm2) electrode footprint and quality and yield were demonstrated; 5) a high-volume manufacturing approach for large-format electrode fabrication was demonstrated; and 6) large-format cells (> 100 Ah capacity) were prototyped with consistent capacity and impedance, including cells which were delivered to Argonne National Laboratory for independent testing.

  20. Cost-Effective Additive Manufacturing in Space: HELIOS Technology Challenge Guide

    Science.gov (United States)

    DeVieneni, Alayna; Velez, Carlos Andres; Benjamin, David; Hollenbeck, Jay

    2012-01-01

    Welcome to the HELIOS Technology Challenge Guide. This document is intended to serve as a general road map for participants of the HELIOS Technology Challenge [HTC] Program and the associated inaugural challenge: HTC-01: Cost-Effective Additive Manufacturing in Space. Please note that this guide is not a rule book and is not meant to hinder the development of innovative ideas. Its primary goal is to highlight the objectives of the HTC-01 Challenge and to describe possible solution routes and pitfalls that such technology may encounter in space. Please also note that participants wishing to demonstrate any hardware developed under this program during any future HELIOS Technology Challenge showcase event(s) may be subject to event regulations to be published separately at a later date.

  1. Credit Constraints and Determinants of the Cost of Capital in Vietnamese Manufacturing

    DEFF Research Database (Denmark)

    Rand, John

    2007-01-01

    This paper examines the extent to which borrowing constraints restrict firm access to credit and identifies individual, firm, and loan characteristics, which determine the cost of capital in Vietnamese manufacturing. Using direct information from a Vietnamese enterprise survey the paper shows...... to have the necessary time to go through the many administrative difficulties in the formal credit system if they want to "seize the day". Finally, collateralized loans face larger interest rates, explained by the significant influence of "policy lending" in Vietnamese credit markets...... that between 14 and 25% of the enterprises are credit constrained, and these enterprises would increase their debt holdings by between 40 and 115% if borrowing constraints were relaxed. Moreover, it emerges that informal credit markets play an important role for fast growing firms. Enterprises do not appear...

  2. Low cost PEMFC generator manufacturing line. The competitiveness and trustability strategy

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Valdemar Stelita; Souza, Adler de; Ferreira, Mauricio S. [NovoCell Energy Systems S.A., Santa Barbara D' Oeste, SP (Brazil)], Email: valdemar.stelita@novocell.ind.br; Muschellack, Erich [Idee Technologies Ltda, Sao Paulo, SP (Brazil)

    2010-07-01

    Concepts of Lean Manufacturing Lines for Polymer Electrolyte Membrane Fuel Cells (PEMFC) have been searched for the last twenty years, with no fully success so far. As this is considered around the world the last barrier to spread the hydrogen economy for universities and science institutions to the normal life of people, we at NovoCell decided six years ago to develop and test all key aspects that can help making it by a 'Low Cost, Feasible and Reliable Production Process'. The present work is a demonstration of the results we achieved, the main characteristics of the prototypes produced from the lines and that will be the base for our commercial operation starting next year. (author)

  3. Economical evolution: microbes reduce the synthetic cost of extracellular proteins.

    Science.gov (United States)

    Smith, Daniel R; Chapman, Matthew R

    2010-08-24

    Protein evolution is not simply a race toward improved function. Because organisms compete for limited resources, fitness is also affected by the relative economy of an organism's proteome. Indeed, many abundant proteins contain relatively high percentages of amino acids that are metabolically less taxing for the cell to make, thus reducing cellular cost. However, not all abundant proteins are economical, and many economical proteins are not particularly abundant. Here we examined protein composition and found that the relative synthetic cost of amino acids constrains the composition of microbial extracellular proteins. In Escherichia coli, extracellular proteins contain, on average, fewer energetically expensive amino acids independent of their abundance, length, function, or structure. Economic pressures have strategically shaped the amino acid composition of multicomponent surface appendages, such as flagella, curli, and type I pili, and extracellular enzymes, including type III effector proteins and secreted serine proteases. Furthermore, in silico analysis of Pseudomonas syringae, Mycobacterium tuberculosis, Saccharomyces cerevisiae, and over 25 other microbes spanning a wide range of GC content revealed a broad bias toward more economical amino acids in extracellular proteins. The synthesis of any protein, especially those rich in expensive aromatic amino acids, represents a significant investment. Because extracellular proteins are lost to the environment and not recycled like other cellular proteins, they present a greater burden on the cell, as their amino acids cannot be reutilized during translation. We hypothesize that evolution has optimized extracellular proteins to reduce their synthetic burden on the cell.

  4. Improving the Sustainability of Office Partition Manufacturing: Balancing Options for Reducing Emissions of Volatile Organic Compounds

    Directory of Open Access Journals (Sweden)

    Marc A. Rosen

    2009-06-01

    Full Text Available Options are examined to improve the sustainability of office partition manufacturing by reducing volatile organic compounds (VOC emissions. Base VOC emissions for a typical plant are estimated using a mass balance approach. Pollution prevention and sustainability measures are assessed using realistic criteria and weightings. Sustainability has been considered from an industry perspective, considering factors like economics, environmental impact, quality, health and safety. Through a case study, it is demonstrated that several advantageous options are available for reducing VOC emissions in manufacturing office furniture partitions, and thereby enhancing the sustainability of that industrial operation. The measures deemed most viable include implementing several best management practices, not painting of non-visible parts, switching gluing processes, recycling solvent and modifying attachments. The results are intended to be balanced so as to improve their acceptability and adoptability by industry. It appears that it would be advantageous for manufacturers of office panels to evaluate the feasibility of these measures and to implement the most appropriate. The results are likely extendable to other operations in the wood furniture industry, and would improve their sustainability.

  5. Activity-based Management of Logistic Costs in a Manufacturing Company: A Case of Increased Visibility of Logistics Costs in a Slovenian Paper Manufacturing Company

    Directory of Open Access Journals (Sweden)

    Julijana Krajnc

    2012-01-01

    Full Text Available Both the transparent reporting of logistics costs and the related accounting of their cost drivers present a significant factor for the successful management of material flows and the related logistics activities in production companies. These costs, which are mainly reported as part of overhead (indirect costs in such companies, usually remain hidden or are not explicitly visible when the traditional method of accounting is applied. The aim of this research is to create a model of activity-based accounting of logistics costs in a production company, and to test its efficiency in the disclosure of logistics costs compared with traditional cost accounting. The application of the model in a production company shows that an activity-based approach discloses as much as 108% more logistics costs at the level of a group of products than the traditional cost-accounting approach. Further, detailed information on logistics costs obtained in this way enables their more efficient management. Key words: logistics costs; activity-based costing; cost allocation; cost visibility; cost management

  6. VARIANTS OF DETERMINING THE MANUFACTURING COST OF A PRODUCT IN A PRODUCTION UNIT IN THE LIGHT OF BALANCE SHEET LAW

    Directory of Open Access Journals (Sweden)

    Marzena STROJEK‐FILUS

    2014-01-01

    Full Text Available The category of the manufacturing cost of a product is one of the most important ones from the point of view of proper valuation of the assets of a production unit, costs of its operations as well as pricing decisions. This article presents the problem of determining the manufacturing cost of a product in terms of balance sheet law. It has been shown that in order to determine this value various methods and options are allowed by this law, by means of which different values of manufacturing cost of a product are obtained. The importance of a proper selection of an allocation key in setilement of indirect production costs has been highlighted as well as the results of using, in certain cases, approved simplifications in the balance sheet law when determining the manufacturing cost of products have been demonstrated. The problem presented in this article is crucial from the point of view of an organization and management of production as well as managerial decision‐making in a company in the area of design of products and processes.

  7. Combined Life Cycle Assessment and Life Cycle Costing in the Eco-Care-Matrix: A case study on the performance of a modernized manufacturing system for glass containers

    DEFF Research Database (Denmark)

    Auer, Johannes; Bey, Niki; Schäfer, Johannes-Marius

    2017-01-01

    The objects of Life Cycle Assessment (LCA) case studies are often individual components or individual products. Studies focusing on larger industrial manufacturing systems are relatively rare. The purpose of this case study was to assess environmental and cost-related performance of an updated...... levers, (ii) efficiency of the LCA process and (iii) their relevance for the speed and cost of the decision-making process. The LCA results of the production stage of the optimized components showed that the largest contributors to the potential environmental impact of the manufacturing system...... glass bottle's GWP showed that it was reduced by about 40% through optimizing the production system. The LCC showed that the modernization pays off after about five years of service life and that the decision for making an Investment should not only be based on the required capital expenditure (CAPEX...

  8. Global cost estimates of reducing carbon emissions through avoided deforestation

    Energy Technology Data Exchange (ETDEWEB)

    Andrasko, K. [U.S. Environmental Protection Agency, Washington, DC (United States); Beach, R. [RTI International, Research Triangle Park, NC (United States); Kindermann, G. [International Institute of Applied Systems Analysis, Laxenburg (Austria); Obersteiner, M. [International Institute of Applied Systems Analysis, Laxenburg (Austria); Rametsteiner, E. [International Institute of Applied Systems Analysis, Laxenburg (Austria); Sathaye, J. [Lawrence Berkeley National Laboratory, Berkeley, CA (United States); Schlamadinger, B. [TerraCarbon, Graz, (Austria); Sohngen, B. [Department of Agricultural, Environmental, and Development Economics, Ohio State University, Columbus, OH (United States); Wunder, S. [Center for International Forestry Research, Belem-PA (Brazil)

    2008-07-15

    Tropical deforestation is estimated to cause about one-quarter of anthropogenic carbon emissions, loss of biodiversity, and other environmental services. United Nations Framework Convention for Climate Change talks are now considering mechanisms for avoiding deforestation (AD), but the economic potential of AD has yet to be addressed. We use three economic models of glboal land use and management to analyze the potential contribution of AD activities to reduced greenhouse gas emissions. AD activities are found to be a competitive, low-cost abatement option. A program providing a 10% reduction in deforestation from 2005 to 2030 could provide 0.3-0.6 Gt (1 Gt = 1 x 105 g) CO2{center_dot}yr-1 in emission reductions and would require $0.4 billion to $1.7 billion{center_dot}yr-1 for 30 years. A 50% reduction in deforestation from 2005 to 2030 could provide 1.5-2.7 Gt CO2{center_dot}yr-1 in emission reductions and would require $17.2 billion to $28.0 billion{center_dot}yr-1. Finally, some caveats to the analysis that could increase costs of AD programs are described.

  9. DEMAND ILLUSION AS A WAY TO REDUCE COSTS

    Directory of Open Access Journals (Sweden)

    Kirill N. Sosnovskij

    2014-01-01

    Full Text Available Article devoted to a technique that reduces costs to retailers, as well as increase the speed of discounted products. This article deals with the laws of visual merchandising that have a significant impact on the implementation of the company’s products. The analysis of the first law, with the subsequent introduction into it of a new additional method. Consider the effect of «Illusion of deficit» arising from the application of the proposed method. The article also defines the basic hypothesis of the existence of methods and effect, and the conditions for their effective implementation. To confirm the effectiveness of the developed method, quantitative surveys are conducted for different age groups creating situational model, which allows respondents to feel as a consumer.

  10. Ultrafast Laser Fabrication of Novel Fiber Mach-Zehnder Interferometer Sensors and Its Cost-Effective Alternative Manufacturing Methods

    Institute of Scientific and Technical Information of China (English)

    Wang Sumei; Jiang Lan; Li Benye; Zhao Longjiang; Yang Jinpeng; Wang Mengmeng; Xiao Hai; Lu Yongfeng; Hai-Lung Tasi

    2011-01-01

    The recent progresses of fiber sensor fabrication in our group are reviewed. Novel inline fiber Mach-Zehnder interferometer (MZI) sensors with various structures are proposed and manufactured by femtosecond laser fabrication and fusion splicing for high-quality sensing of refractivity-sensitive parameters such as temperature, concentration, humidity, pressure, stress and strain., a) for an MZI sensor with a trench on a single-mode fiber, the refractive index (RI) sensitivity of acetone vapor is about 10 nm/RIU (refractive index unit) and the temperature sensitivity is 51.5 pm/℃ from 200 to 875℃ ; b) For an MZI consisting of two micro-air-cavities, the sensitivity is501.5 nm/RIU and the detection limit is 1. 994 × 10 RIU at the refractive index of 1.4; c) to reduce the fabrication cost, a new fusion-splicing based method is proposed to fabricate MZI sensors; the sensitivity is 664.57 nm/RIU witha detection limit of 1.5 x 10 RIU and its cost is tens of times cheaper than those of commercialized long period fiber Gratings; Also, 5×10 acetone vapors are successfully detected by the MZI sensors coated with zeolite thin films.

  11. Insulator coated magnetic nanoparticulate composites with reduced core loss and method of manufacture thereof

    Science.gov (United States)

    Zhang, Yide (Inventor); Wang, Shihe (Inventor); Xiao, Danny (Inventor)

    2004-01-01

    A series of bulk-size magnetic/insulating nanostructured composite soft magnetic materials with significantly reduced core loss and its manufacturing technology. This insulator coated magnetic nanostructured composite is comprises a magnetic constituent, which contains one or more magnetic components, and an insulating constituent. The magnetic constituent is nanometer scale particles (1-100 nm) coated by a thin-layered insulating phase (continuous phase). While the intergrain interaction between the immediate neighboring magnetic nanoparticles separated by the insulating phase (or coupled nanoparticles) provide the desired soft magnetic properties, the insulating material provides the much demanded high resistivity which significantly reduces the eddy current loss. The resulting material is a high performance magnetic nanostructured composite with reduced core loss.

  12. MODIFICATIONS TO REDUCE DRAG OUT AT A PRINTED CIRCUIT BOARD MANUFACTURER

    Science.gov (United States)

    This MnTAP/EPA Waste Reduction Innovative Technology Evaluation project at Micom, Inc., demonstrated the waste reducing capability of two simple rinsing modifications on an etchant and an electroless copper process. he simple, tow (or no) cost, low technology changes that were ma...

  13. Low-Cost Manufacturing Technique for Advanced Regenerative Cooling for In-Space Cryogenic Engines Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal of the proposed effort is to use selective laser melting (SLM, an additive manufacturing technique) to manufacture a hot fire-capable, water-cooled spool...

  14. Low-Cost Manufacturing Technique for Advanced Regenerative Cooling for In-Space Cryogenic Engines Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal of the proposed effort is to demonstrate feasibility of using selective laser melting (SLM, an emerging manufacturing technique) to manufacture a subscale...

  15. Reduced toxicity polyester resins and microvascular pre-preg tapes for advanced composites manufacturing

    Science.gov (United States)

    Poillucci, Richard

    Advanced composites manufacturing broadly encapsulates topics ranging from matrix chemistries to automated machines that lay-up fiber-reinforced materials. Environmental regulations are stimulating research to reduce matrix resin formulation toxicity. At present, composites fabricated with polyester resins expose workers to the risk of contact with and inhalation of styrene monomer, which is a potential carcinogen, neurotoxin, and respiratory irritant. The first primary goal of this thesis is to reduce the toxicity associated with polyester resins by: (1) identification of potential monomers to replace styrene, (2) determination of monomer solubility within the polyester, and (3) investigation of approaches to rapidly screen a large resin composition parameter space. Monomers are identified based on their ability to react with polyester and their toxicity as determined by the Globally Harmonized System (GHS) and a green screen method. Solubilities were determined by the Hoftyzer -- Van Krevelen method, Hansen solubility parameter database, and experimental mixing of monomers. A combinatorial microfluidic mixing device is designed and tested to obtain distinct resin compositions from two input chemistries. The push for safer materials is complemented by a thrust for multifunctional composites. The second primary goal of this thesis is to design and implement the manufacture of sacrificial fiber materials suitable for use in automated fiber placement of microvascaular multifunctional composites. Two key advancements are required to achieve this goal: (1) development of a roll-to-roll method to place sacrificial fibers onto carbon fiber pre-preg tape; and (2) demonstration of feasible manufacture of microvascular carbon fiber plates with automated fiber placement. An automated method for placing sacrificial fibers onto carbon fiber tapes is designed and a prototype implemented. Carbon fiber tows with manual placement of sacrificial fibers is implemented within an

  16. Routes to increasing efficiency and reducing the cost of thin-film solar panels

    NARCIS (Netherlands)

    Deelen, J. van; Barink, M.; Klerk, L.; Voorthuijzen, P.; Hovestad, A.

    2015-01-01

    Most development work in the laboratory is dedicated to efficiency enhancements at the cell level; improvements in efficiency can lead to higher cost-competitiveness of PV. However, the cost of panel manufacturing is an important aspect as well. For CIGS panels the deposition of the active layer is

  17. Routes to increasing efficiency and reducing the cost of thin-film solar panels

    NARCIS (Netherlands)

    Deelen, J. van; Barink, M.; Klerk, L.; Voorthuijzen, P.; Hovestad, A.

    2015-01-01

    Most development work in the laboratory is dedicated to efficiency enhancements at the cell level; improvements in efficiency can lead to higher cost-competitiveness of PV. However, the cost of panel manufacturing is an important aspect as well. For CIGS panels the deposition of the active layer is

  18. Gauging the feasibility of cost-sharing and medical student interest groups to reduce interview costs.

    Science.gov (United States)

    Lieber, Bryan A; Wilson, Taylor A; Bell, Randy S; Ashley, William W; Barrow, Daniel L; Wolfe, Stacey Quintero

    2014-11-01

    Indirect costs of the interview tour can be prohibitive. The authors sought to assess the desire of interviewees to mitigate these costs through ideas such as sharing hotel rooms and transportation, willingness to stay with local students, and the preferred modality to coordinate this collaboration. A survey link was posted on the Uncle Harvey website and the Facebook profile page of fourth-year medical students from 6 different medical schools shortly after the 2014 match day. There were a total of 156 respondents to the survey. The majority of the respondents were postinterview medical students (65.4%), but preinterview medical students (28.2%) and current residents (6.4%) also responded to the survey. Most respondents were pursuing a field other than neurosurgery (75.0%) and expressed a desire to share a hotel room and/or transportation (77.4%) as well as stay in the dorm room of a medical student at the program in which they are interviewing (70.0%). Students going into neurosurgery were significantly more likely to be interested in sharing hotel/transportation (89.2% neurosurgery vs 72.8% nonneurosurgery; p = 0.040) and in staying in the dorm room of a local student when on interviews (85.0% neurosurgery vs 57.1% nonneurosurgery; p = 0.040) than those going into other specialties. Among postinterview students, communication was preferred to be by private, email identification-only chat room. Given neurosurgery resident candidates' interest in collaborating to reduce interview costs, consideration should be given to creating a system that could allow students to coordinate cost sharing between interviewees. Moreover, interviewees should be connected to local students from neurosurgery interest groups as a resource.

  19. High Temperature Thermoplastic Additive Manufacturing Using Low-Cost, Open-Source Hardware

    Science.gov (United States)

    Gardner, John M.; Stelter, Christopher J.; Yashin, Edward A.; Siochi, Emilie J.

    2016-01-01

    Additive manufacturing (or 3D printing) via Fused Filament Fabrication (FFF), also known as Fused Deposition Modeling (FDM), is a process where material is placed in specific locations layer-by-layer to create a complete part. Printers designed for FFF build parts by extruding a thermoplastic filament from a nozzle in a predetermined path. Originally developed for commercial printers, 3D printing via FFF has become accessible to a much larger community of users since the introduction of Reprap printers. These low-cost, desktop machines are typically used to print prototype parts or novelty items. As the adoption of desktop sized 3D printers broadens, there is increased demand for these machines to produce functional parts that can withstand harsher conditions such as high temperature and mechanical loads. Materials meeting these requirements tend to possess better mechanical properties and higher glass transition temperatures (Tg), thus requiring printers with high temperature printing capability. This report outlines the problems and solutions, and includes a detailed description of the machine design, printing parameters, and processes specific to high temperature thermoplastic 3D printing.

  20. Autonomous exoskeleton reduces metabolic cost of human walking.

    Science.gov (United States)

    Mooney, Luke M; Rouse, Elliott J; Herr, Hugh M

    2014-11-03

    Passive exoskeletons that assist with human locomotion are often lightweight and compact, but are unable to provide net mechanical power to the exoskeletal wearer. In contrast, powered exoskeletons often provide biologically appropriate levels of mechanical power, but the size and mass of their actuator/power source designs often lead to heavy and unwieldy devices. In this study, we extend the design and evaluation of a lightweight and powerful autonomous exoskeleton evaluated for loaded walking in (J Neuroeng Rehab 11:80, 2014) to the case of unloaded walking conditions. The metabolic energy consumption of seven study participants (85 ± 12 kg body mass) was measured while walking on a level treadmill at 1.4 m/s. Testing conditions included not wearing the exoskeleton and wearing the exoskeleton, in both powered and unpowered modes. When averaged across the gait cycle, the autonomous exoskeleton applied a mean positive mechanical power of 26 ± 1 W (13 W per ankle) with 2.12 kg of added exoskeletal foot-shank mass (1.06 kg per leg). Use of the leg exoskeleton significantly reduced the metabolic cost of walking by 35 ± 13 W, which was an improvement of 10 ± 3% (p = 0.023) relative to the control condition of not wearing the exoskeleton. The results of this study highlight the advantages of developing lightweight and powerful exoskeletons that can comfortably assist the body during walking.

  1. Preliminary estimate of the manufacturing cost for lithium/metal sulfide cells for stationary and mobile applications

    Energy Technology Data Exchange (ETDEWEB)

    Chilenskas, A. A.; Schaefer, J. C.; Towle, W. L.; Barney, D. L.

    1980-01-01

    A preliminary estimate has been made of the manufacturing cost for lithium/iron sulfide cells for stationary energy-storage and electric-vehicle applications. This preliminary cost analysis indicated that the manufacturing cost (in 1979 dollars) is $24 to 41/kW-h for stationary energy-storage cells and $31 to 55/kW-h for electric-vehicle cells. The materials cost was found to contribute between 52 and 65% of this manufacturing cost. The most expensive materials and components were lithium (metal and compounds), $4.61 to $14.26/kW-h; BN felt, $4.00 to 8.50/kW-h; feed-through components, $2.40/kW-h; positive current collectors, $1.48 to 2.20/kW-h; and aluminum, $1.43 to 1.66/kW-h. The projected lithium requirements were determined for use in lithium/iron sulfide batteries and conventional uses to the year 2006. The results showed that the lithium requirements were about 275,000 short tons by 2006, which is equivalent to about 51% of presently known US resources. Of this amount, about 33% would be used in battery production and 67% consumed in conventional uses. It is expected that the lithium used in battery production would be recycled.

  2. Potentials for Improvement of Resource Efficiency in Printed Circuit Board Manufacturing: A Case Study Based on Material Flow Cost Accounting

    Directory of Open Access Journals (Sweden)

    Yi-Xuan Wang

    2017-05-01

    Full Text Available The pursuit of sustainable resource use by manufacturing companies is driven by resource scarcity, environmental awareness, and cost savings potentials. To address these issues, Material Flow Cost Accounting (MFCA has been developed and applied as an effective environmental management tool. Within MFCA’s general allocation, the accounts of products and losses are overrated by weight or volume. However, such a method is incompatible with Printed Circuit Board (PCB manufacturing because of industry characteristics in which primary inputs and products are measured by area. Based on MFCA, this case study systematically established several linear cost calculation models along the production process for capturing the actual waste flows as well as performing cost-benefit analysis. The recognition of previously ignored losses offered the incentive to find appropriate indicators to conduct cost-benefit analysis on hotspots for losses. Loss identification and analysis indicated that machining and wiring are the necessities and priorities of process optimization for resource efficiency improvement measures. Therefore, this research could not only advance the achievement of a profitable and sustainable production while improving resource efficiency at the source but could also provide support for decision making in PCB manufacturing.

  3. Lean Six Sigma for Reduced Cycle Costs and Improved Readiness

    Science.gov (United States)

    2006-09-30

    Management principles of Frederic Taylor (1911) and to the practical genius of Henry Ford (Levinson, 2002). But the principles of Lean Production were...NJ: Pearson Education. Coale, S. (2006). Expanding Lean beyond the manufacturing floor. Air Force Link. Retrieved September 12, 2006, from http

  4. Use of Information System and lean manufacturing to reduce the waste in the process industry

    Directory of Open Access Journals (Sweden)

    Abhishek Kumar Singh

    2013-03-01

    Full Text Available The objective of this paper is to introduce the work of information technology in the process industry. In the industry the time is used as the money. So here the main task is to save time. In the industry the maximum time spent due to the waste. Lean Manufacturing is a term that is used to reduce the waste from the industry. It also use the information system in the form of Kanban. Lean principles and techniques have been applied in a wide variety of organizations, from make-to-stock to engineer-to-order industries, and even in typical service sectors, such as healthcare. In order to apply lean principles in various areas, variants were developed of well known techniques, such as Kanban, Kaizen, SMED, and 5S. Here the discrete and continuous manufacturing benefits are distinguished by the value stream mapping. Here the Value stream mapping is used to first map the current state and then used to identify sources of waste and to identify lean tools to try to eliminate this waste. The future state map is then developed for a system with lean tools applied to it. This thesis focuseson the development of a simulation model of the industry.

  5. A Manufacturing Cost and Supply Chain Analysis of SiC Power Electronics Applicable to Medium-Voltage Motor Drives

    Energy Technology Data Exchange (ETDEWEB)

    Horowitz, Kelsey [National Renewable Energy Lab. (NREL), Golden, CO (United States); Remo, Timothy [National Renewable Energy Lab. (NREL), Golden, CO (United States); Reese, Samantha [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2017-03-24

    Wide bandgap (WBG) semiconductor devices are increasingly being considered for use in certain power electronics applications, where they can improve efficiency, performance, footprint, and, potentially, total system cost compared to systems using traditional silicon (Si) devices. Silicon carbide (SiC) devices in particular -- which are currently more mature than other WBG devices -- are poised for growth in the coming years. Today, the manufacturing of SiC wafers is concentrated in the United States, and chip production is split roughly equally between the United States, Japan, and Europe. Established contract manufacturers located throughout Asia typically carry out manufacturing of WBG power modules. We seek to understand how global manufacturing of SiC components may evolve over time by illustrating the regional cost drivers along the supply chain and providing an overview of other factors that influence where manufacturing is sited. We conduct this analysis for a particular case study where SiC devices are used in a medium-voltage motor drive.

  6. Energy-efficient induction motors designing with application of a modified criterion of reduced costs

    Directory of Open Access Journals (Sweden)

    V.S. Petrushin

    2014-03-01

    Full Text Available The paper introduces a modified criterion of reduced costs that employs coefficients of operation significance and priority of ohmic loss accounting to allow matching maximum efficiency with minimum reduced costs. Impact of the inflation factor on the criterion of reduced costs is analyzed.

  7. How employers can reduce the cost of their disability programs.

    Science.gov (United States)

    Nemeth, J M; Borgenicht, L

    1997-01-01

    The rapid rate at which disability costs are rising is fueling the need to cut costs. This article details some strategies that employers can utilize to help keep disability costs under control. The authors discuss many difficult issues that need to be addressed to make productive changes to the existing status quo, which needs to be assessed for current strengths and weaknesses before changes can be made. Case studies are presented and many alternative plan designs are discussed that could involve varying cost savings depending upon the individual plan characteristics.

  8. Reducing the Cost of Laparoscopy: Reusable versus Disposable Laparoscopic Instruments

    Directory of Open Access Journals (Sweden)

    Dimitrios K. Manatakis

    2014-01-01

    Full Text Available Cost-effectiveness in health care management is critical. The situation in debt-stricken Greece is further aggravated by the financial crisis and constant National Health System expense cut-downs. In an effort to minimize the cost of laparoscopy, our department introduced reusable laparoscopic instruments in December 2011. The aim of this study was to assess potential cost reduction of laparoscopic operations in the field of general surgery. Hospital records, invoice lists, and operative notes between January 2012 and December 2013, were retrospectively reviewed and data were collected on laparoscopic procedures, instrument failures, and replacement needs. Initial acquisition cost of 5 basic instrument sets was €21,422. Over the following 24 months, they were used in 623 operations, with a total maintenance cost of €11,487. Based on an average retail price of €490 per set, projected cost with disposable instruments would amount to €305,270, creating savings of €272,361 over the two-year period under study. Despite the seemingly high purchase price, each set amortized its acquisition cost after only 9 procedures and instrument cost depreciated to less than €55 per case. Disposable instruments cost 9 times more than reusable ones, and their high price would almost equal the total hospital reimbursement by social security funds for many common laparoscopic procedures.

  9. The Effect of Adopting New Storage Methods for Extending Product Validity Periods on Manufacturers Expected Inventory Costs

    Directory of Open Access Journals (Sweden)

    Po-Yu Chen

    2014-01-01

    Full Text Available The validness of the expiration dates (validity period that manufacturers provide on food product labels is a crucial food safety problem. Governments must study how to use their authority by implementing fair awards and punishments to prompt manufacturers into adopting rigorous considerations, such as the effect of adopting new storage methods for extending product validity periods on expected costs. Assuming that a manufacturer sells fresh food or drugs, this manufacturer must respond to current stochastic demands at each unit of time to determine the purchase amount of products for sale. If this decision maker is capable and an opportunity arises, new packaging methods (e.g., aluminum foil packaging, vacuum packaging, high-temperature sterilization after glass packaging, or packaging with various degrees of dryness or storage methods (i.e., adding desiccants or various antioxidants can be chosen to extend the validity periods of products. To minimize expected costs, this decision maker must be aware of the processing costs of new storage methods, inventory standards, inventory cycle lengths, and changes in relationships between factors such as stochastic demand functions in a cycle. Based on these changes in relationships, this study established a mathematical model as a basis for discussing the aforementioned topics.

  10. REDUCING THE REJECTION RATE OF ENGINES MANUFACTURING DUE TO INJECTION TIMING VARIATION

    Directory of Open Access Journals (Sweden)

    Mrs. P.SIVASHANKARI

    2015-12-01

    Full Text Available The white paper is on HINO 6 cylinder engine and the aim is to reduce the rejection rate of engines during testing due to the problems occur in valve timing and injection timing. The concept of Six Sigma is mainly practiced as a design to eliminate the production defects by improving the process of manufacturing. In the observation, the injection timing mark (spill mark is not perfectly done and also the imperfection in flywheel marking machine locator pin increases engine rejection. The aim is to eliminate the engines getting rejected during engine test due to problems arising in the injection timing and valve timing. As there are a lot of problems arising in the test bed where the engine is tested, few of which are related to injection timing and valve timing. These problems mainly arise due to changes in the valve and injection timing variation.

  11. Lean Manufacturing - A Powerfull Tool for Reducing Waste During the Processes

    OpenAIRE

    Mihai Apreutesei; Emil Suciu; Ionela Roxana Arvinte

    2010-01-01

    Lean manufacturing provides a new management approach for many small and medium size manufacturers, especially older firms organized and managed under traditional push systems. Improvement results can be dramatic in terms of quality, cycle times, and customer responsiveness. Lean manufacturing is more than a set of tools and techniques and has been widely adopted by many production companies. Lean manufacturing is a culture in which all employees continuously look for ways to improve processe...

  12. Advanced Fuels Can Reduce the Cost of Getting Into Space

    Science.gov (United States)

    Palaszewski, Bryan A.

    1998-01-01

    Rocket propellant and propulsion technology improvements can reduce the development time and operational costs of new space vehicle programs, and advanced propellant technologies can make space vehicles safer and easier to operate, and can improve their performance. Five major areas have been identified for fruitful research: monopropellants, alternative hydrocarbons, gelled hydrogen, metallized gelled propellants, and high-energy-density propellants. During the development of the NASA Advanced Space Transportation Plan, these technologies were identified as those most likely to be effective for new NASA vehicles. Several NASA research programs had fostered work in fuels under the topic Fuels and Space Propellants for Reusable Launch Vehicles in 1996 to 1997. One component of this topic was to promote the development and commercialization of monopropellant rocket fuels, hypersonic fuels, and high-energy-density propellants. This research resulted in the teaming of small business with large industries, universities, and Government laboratories. This work is ongoing with seven contractors. The commercial products from these contracts will bolster advanced propellant research. Work also is continuing under other programs, which were recently realigned under the "Three Pillars" of NASA: Global Civil Aviation, Revolutionary Technology Leaps, and Access to Space. One of the five areas is described below, and its applications and effect on future missions is discussed. This work is being conducted at the NASA Lewis Research Center with the assistance of the NASA Marshall Space Flight Center. The regenerative cooling of spacecraft engines and other components can improve overall vehicle performance. Endothermic fuels can absorb energy from an engine nozzle and chamber and help to vaporize high-density fuel before it enters the combustion chamber. For supersonic and hypersonic aircraft, endothermic fuels can absorb the high heat fluxes created on the wing leading edges and

  13. Kickbacks, courtesies or cost-effectiveness?: Application of the Medicare antikickback Law to the marketing and promotional practices of drug and medical device manufacturers.

    Science.gov (United States)

    Bulleit, T N; Krause, J H

    1999-01-01

    This article summarizes the purposes and history of the antikickback law and describes its evolution into a potent weapon against the corruption of medical decision making in the procurement of prescription drugs and medical devices. The article also details a variety of strategies for reducing risks under the law in several key areas of importance to manufacturers. While the purposes of the law are laudable, its current broad interpretation may impede not only corruption, but also benign forms of customer relations and innovative approaches to cost-effective medical care.

  14. Management Accounting in the Manufacturing Sector: Managing Costs at the Design and Production Stages

    NARCIS (Netherlands)

    Davila, Tony; Wouters, Marc; Chapman, Christopher S.; Hopwood, Anthony G.; Shields, Michael D.

    2006-01-01

    This chapter analyzes the empirical research literature on management accounting in the manufacturing sector including the development as well and manufacturing phases of the product lifecycle. As managing product development has gained terrain in companies over the last 15 years, management

  15. Management Accounting in the Manufacturing Sector: Managing Costs at the Design and Production Stages

    NARCIS (Netherlands)

    Davila, Tony; Wouters, Marc; Chapman, Christopher S.; Hopwood, Anthony G.; Shields, Michael D.

    2006-01-01

    This chapter analyzes the empirical research literature on management accounting in the manufacturing sector including the development as well and manufacturing phases of the product lifecycle. As managing product development has gained terrain in companies over the last 15 years, management account

  16. Do volunteers reduce the costs of parent training programs?

    DEFF Research Database (Denmark)

    Scavenius Sonne-Schmidt, Christoffer; Amilon, Anna; Schultz, Esben Anton

    costs. This study evaluates the cost-effectiveness of the volunteer-delivered parent training program Caring in Chaos. The analyses show that Caring in Chaos is as effective as similar programs while the recurrent costs associated with the program are substantially lower than that of (other) similar......ADHD in children has considerable negative consequences for both affected individuals and their families. One way to milden these negative consequences is by offering parents training in how to handle the child’s difficulties. However, running parent training programs is associated with substantial...

  17. Reducing Operating Costs and Energy Consumption at Water Utilities

    Science.gov (United States)

    Due to their unique combination of high energy usage and potential for significant savings, utilities are turning to energy-efficient technologies to help save money. Learn about cost and energy saving technologies from this brochure.

  18. Reduced Cost Composite Hot Structures with Oxidation Protection Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Innovative, low cost high performance technologies are critical to the affordability of future space missions. Carbon/carbon (C/C) composites have significant...

  19. Quality Improvement ? The Key to Reducing Costs in Pancreatoduodenectomy

    Directory of Open Access Journals (Sweden)

    Savio George Barreto

    2016-03-01

    Full Text Available Background With the looming fear of costs for cancer care escalating over the next decade, the general aim of policy makers the world over is directing efforts towards “bending the cost curve”. Pancreatic cancer is on the rise and pancreatoduodenectomy is the only curative option available. The aim of the current report is to analyze the published literature on data addressing the issue of costs in pancreatic cancer surgery (with a focus on pancreatoduodenectomy in an effort to determine how disparate are the lines of investigation of health economics and quality indicators of surgery. Methods A systematic and comprehensive search of major reference databases (MEDLINE, EMBASE, PubMed, and the Cochrane Library was undertaken using a combination of text words “cost”, “pancreatoduodenectomy”, “pancreaticoduodenectomy”, “health care”, “surgery”. The search was restricted to human studies published in literature but was not language restricted. Results The initial search yielded 116 studies of which 25 manuscripts were retrieved for further evaluation. Of the 25 studies retrieved, 7 manuscripts were excluded from the final analysis as the variables analyzed did not significantly influence the costs of pancreatoduodenectomy. The factors most frequently noted (≥2 studies to influence costs of pancreatoduodenectomy were hospital and surgeon volume the occurrence of complications and the implementation of clinical pathways. Conclusions Using pancreatoduodenectomy, as an example, it is evident that the key to ‘bending the cancer cost curve’ is designing strategies to improve quality of the not only the procedure, but the process. Costs and quality cannot be separated. Reduction in costs can, and must only, be achieved by targeting excellence.

  20. Development of Production PVD-AIN Buffer Layer System and Processes to Reduce Epitaxy Costs and Increase LED Efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Cerio, Frank

    2013-09-14

    The DOE has set aggressive goals for solid state lighting (SSL) adoption, which require manufacturing and quality improvements for virtually all process steps leading to an LED luminaire product. The goals pertinent to this proposed project are to reduce the cost and improve the quality of the epitaxial growth processes used to build LED structures. The objectives outlined in this proposal focus on achieving cost reduction and performance improvements over state-of-the-art, using technologies that are low in cost and amenable to high efficiency manufacturing. The objectives of the outlined proposal focus on cost reductions in epitaxial growth by reducing epitaxy layer thickness and hetero-epitaxial strain, and by enabling the use of larger, less expensive silicon substrates and would be accomplished through the introduction of a high productivity reactive sputtering system and an effective sputtered aluminum-nitride (AlN) buffer/nucleation layer process. Success of the proposed project could enable efficient adoption of GaN on-silicon (GaN/Si) epitaxial technology on 150mm silicon substrates. The reduction in epitaxy cost per cm{sup 2} using 150mm GaN-on-Si technology derives from (1) a reduction in cost of ownership and increase in throughput for the buffer deposition process via the elimination of MOCVD buffer layers and other throughput and CoO enhancements, (2) improvement in brightness through reductions in defect density, (3) reduction in substrate cost through the replacement of sapphire with silicon, and (4) reduction in non-ESD yield loss through reductions in wafer bow and temperature variation. The adoption of 150mm GaN/Si processing will also facilitate significant cost reductions in subsequent wafer fabrication manufacturing costs. There were three phases to this project. These three phases overlap in order to aggressively facilitate a commercially available production GaN/Si capability. In Phase I of the project, the repeatability of the performance

  1. Managing concrete bridges: Methods for reducing costs and user inconveniences

    DEFF Research Database (Denmark)

    Goltermann, Per

    2005-01-01

    The paper presents experiences from modern bridge maintenance management, which has been forced to develop new and cost-efficient approaches in order to cope with the increase in overall deterioration of the aging bridge stock, the growing requirements to accessibility and the decreasing budgets....... These approaches are focused on cost reductions, but must as well lead to a reduction of the user inconveniences (traffic delays, noise, dust) and to a reduction of the environmental impact. These approaches can be based on an assessment of the structures safety, which incorporates the inaccuracies...... in the condition assessments, the models and the predictions in the strategies and the cost estimations. This may lead to increased inspection frequencies, detailed simulations, monitoring and testing to be used as alternatives to extensive repairs, rehabilitations or strengthening. The approaches will in other...

  2. Determination of the optimal time and cost of manufacturing flow of an assembly using the Taguchi method

    Science.gov (United States)

    Petrila, S.; Brabie, G.; Chirita, B.

    2016-08-01

    The optimization of the parts and assembly manufacturing operation was carried out in order to minimize both the time and cost of production as appropriate. The optimization was made by using the Taguchi method. The Taguchi method is based on the plans of experiences that vary the input and outputs factors. The application of the Taguchi method in order to optimize the flow of the analyzed assembly production is made in the following: to find the optimal combination between the manufacturing operations; to choose the variant involving the use of equipment performance; to delivery operations based on automation. The final aim of the Taguchi method application is that the entire assembly to be achieved at minimum cost and in a short time. Philosophy Taguchi method of optimizing product quality is synthesized from three basic concepts: quality must be designed into the product and not he product inspected after it has been manufactured; the higher quality is obtained when the deviation from the proposed target is low or when uncontrollable factors action has no influence on it, which translates robustness; costs entailed quality are expressed as a function of deviation from the nominal value [1]. When determining the number of experiments involving the study of a phenomenon by this method, follow more restrictive conditions [2].

  3. Advanced Manufacturing Technologies (AMT): Low Cost Upper Stage-Class Propulsion Development Element

    Data.gov (United States)

    National Aeronautics and Space Administration — As manufacturing technologies have matured, it now appears possible to build all the major components and subsystems of an upper stage-class rocket engine for...

  4. Reducing maintenance costs in agreement with CNC machine tools reliability

    Science.gov (United States)

    Ungureanu, A. L.; Stan, G.; Butunoi, P. A.

    2016-08-01

    Aligning maintenance strategy with reliability is a challenge due to the need to find an optimal balance between them. Because the various methods described in the relevant literature involve laborious calculations or use of software that can be costly, this paper proposes a method that is easier to implement on CNC machine tools. The new method, called the Consequence of Failure Analysis (CFA) is based on technical and economic optimization, aimed at obtaining a level of required performance with minimum investment and maintenance costs.

  5. Non-aerated burner reduces drying costs; Diffusiebrander maakt drogen goedkoper

    Energy Technology Data Exchange (ETDEWEB)

    Koopman, F.P. [Gasunie Research, Groningen (Netherlands)

    1998-10-01

    Gas-fired tumble dryers are more expensive than electric dryers. However, consumers appear to be more satisfied about the drying results of gas-fired tumble dryers. Since premix burner lead to higher natural gas conversion costs, Gasunie Research developed a non-aerated burner, featuring a simple design and a limited number of parts. Moreover, it can be manufactured at low cost, which should improve the competitiveness of the gas-fired tumble dryer

  6. Materials Testing and Cost Modeling for Composite Parts Through Additive Manufacturing

    Science.gov (United States)

    2016-04-30

    manufacturing: The case of lightweight aircraft components. Journal of Cleaner Production . http://dx.doi.org/doi:10.1016/j.jclepro.2015.04.109 Lindemann, C...and conventional tool and die manufacturing. Journal of Cleaner Production , 15, 932–943. Namiki, M., Ueda, M., Todoroki, A., Hirano, Y., & Matsuzaki...process and conventional machining implementing life-cycle assessment. Journal of Cleaner Production , 19, 1117–1124. Tuck, C., Hague, R., Ruffo, M

  7. Manufacture of reduced-sodium Cheddar-style cheese with mineral salt replacers.

    Science.gov (United States)

    Grummer, J; Karalus, M; Zhang, K; Vickers, Z; Schoenfuss, T C

    2012-06-01

    The use of mineral salt replacers to reduce the sodium content in cheese has been investigated as a method to maintain both the salty flavor and the preservative effects of salt. The majority of studies of sodium reduction have used mineral salt replacers at levels too low to produce equal water activity (a(w)) in the finished cheese compared with the full-sodium control. Higher a(w) can result in differences in cheese quality due to differences in the effective salt-to-moisture ratio. This creates differences in biochemical and microbial reactions during aging. We hypothesized that by targeting replacer concentrations to produce the same a(w) as full sodium cheese, changes in cheese quality would be minimized. Stirred-curd Cheddar-style cheese was manufactured and curd was salted with NaCl or naturally reduced sodium sea salt. Reduced-sodium cheeses were created by blends of NaCl or sea salt with KCl, modified KCl, MgCl₂, or CaCl₂ before pressing. Sodium levels in reduced-sodium cheeses ranged from 298 to 388 mg of sodium/100g, whereas the control full-sodium cheese had 665 mg/100g. At 1 wk of age, a(w) of reduced-sodium cheeses were not significantly different from control, which had an a(w) of 0.96. The pH values of all reduced-sodium cheeses, excluding the treatment that combined sea salt and MgCl₂, were lower than those of full-sodium cheese, indicating that the starter culture was possibly less inhibited at the salting step by the replacers than by NaCl. Instrumental hardness values of the treatments with sea salt were higher than in cheeses containing NaCl, with the exception of the NaCl/CaCl₂ treatment, which was the hardest. Treatments with MgCl₂ and modified KCl were generally less hard than other treatments. In-hand and first-bite firmness values correlated with the instrumental texture profile analysis results. Both CaCl₂ and MgCl₂ produced considerable off-flavors in the cheese (bitter, metallic, unclean, and soapy), as measured by

  8. Reducing High Absenteeism through Low-Cost Incentives.

    Science.gov (United States)

    North Chaplik, Barbara D.; Engel, Ross A.

    1984-01-01

    Describes a study of the effects of a low-cost incentive program--including daily, weekly, and monthly reinforcements such as attention, approval, and inexpensive awards--on the absenteeism of high-absence employees in an urban school district's transportation department. A 20-percent reduction in absenteeism was achieved. (TE)

  9. Management Science/Industrial Engineering Techniques to Reduce Food Costs.

    Science.gov (United States)

    Greenberg, Murray

    This paper examines the contributions of Industrial Engineering and Management Science toward reduction in the cost of production and distribution of food. Food processing firms were requested to respond to a questionnaire which asked for examples of their use of various operations research tools and information on the number of operations…

  10. Reducing Building HVAC Costs with Site-Recovery Energy

    Science.gov (United States)

    Pargeter, Stephen J.

    2012-01-01

    Building owners are caught between two powerful forces--the need to lower energy costs and the need to meet or exceed outdoor air ventilation regulations for occupant health and comfort. Large amounts of energy are wasted each day from commercial, institutional, and government building sites as heating, ventilation, and air conditioning (HVAC)…

  11. Improving the Defense Acquisition System and Reducing System Costs

    Science.gov (United States)

    1981-03-30

    DDTE NAVMATO 421 HQ U3AF/ LEYE PA&E DSB/OP-098R NAVAIR (Air-41) CSD/PA&E . ASA (R, D, A) CSD (MRA&L) DA/DSLOG CSD (Ccmpt) Proj 72...a layered and collateral management structure created by the need to control different " colors " of money. This can all result in total system cost

  12. The practice of quality-associated costing: application to transfusion manufacturing processes.

    Science.gov (United States)

    Trenchard, P M; Dixon, R

    1997-01-01

    This article applies the new method of quality-associated costing (QAC) to the mixture of processes that create red cell and plasma products from whole blood donations. The article compares QAC with two commonly encountered but arbitrary models and illustrates the invalidity of clinical cost-benefit analysis based on these models. The first, an "isolated" cost model, seeks to allocate each whole process cost to only one product class. The other is a "shared" cost model, and it seeks to allocate an approximately equal share of all process costs to all associated products.

  13. Study of the manufacturing costs of lead--acid batteries for peaking power. Final report for the period ending Oct. 1976

    Energy Technology Data Exchange (ETDEWEB)

    None

    1976-12-01

    A detailed study was made of a postulated 1000-MWh per year lead--acid battery business dedicated to supplying a single design of 40-MWh peaking power batteries to electric utilities. State-of-the-art industrial technology is assumed, but the manufacturing facility and business organization is tailored to the one product. Analysis of the product costs and business expenses associated with such an operation indicates that substantially lower selling prices can be realized as compared with normal industrial battery pricing. Under the low-risk conditions assumed, the selling price would be $36.90/kWh at the 4-h rate. Advanced technology would reduce the cost to $31.62/kWh. 21 figures, 31 tables. (RWR)

  14. A method for reducing software life cycle costs

    Science.gov (United States)

    Paine, W. O.; Holland, J. C.

    1977-01-01

    The advent of new hardware and software tools permits a new approach to preparing, presenting, and maintaining software specifications and corresponding source programs. Any real reduction in software life cycle costs must make highly skilled human effort more efficient especially on large, complex, and long-lasting software projects. When these skilled human functions are examined closely, it is seen that critical factors include the way one communicates with oneself and then with others and finally with computers. Thus, there has been a long and active proliferation of programming languages and, more recently, a number of programming design languages to supplement older methods, such as flowcharting. One way to achieve cost reduction is to provide documentation tools whose use increases the effectiveness of skilled humans.

  15. Lean Six Sigma for Reduced Cycle Costs and Improved Readiness

    OpenAIRE

    Apte, Uday; Keebom Kang

    2006-01-01

    Sponsored Report (for Acquisition Research Program) In general, during the lifecycle of a weapon system a significantly larger amount of money gets spent in operating and maintaining the system than acquiring it. Hence, efficient logistics systems, including transportation, inventory management, modifications and maintenance activities, are critically important for containing the lifecycle costs of weapon systems and for maintaining the highest level of military readiness given the extant ...

  16. Low-cost Electromagnetic Heating Technology for Polymer Extrusion-based Additive Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Carter, William G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Rios, Orlando [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Akers, Ronald R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Morrison, William A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-01-07

    To improve the flow of materials used in in polymer additive manufacturing, ORNL and Ajax Tocco created an induction system for heating fused deposition modeling (FDM) nozzles used in polymer additive manufacturing. The system is capable of reaching a temperature of 230 C, a typical nozzle temperature for extruding ABS polymers, in 17 seconds. A prototype system was built at ORNL and sent to Ajax Tocco who analyzed the system and created a finalized power supply. The induction system was mounted to a PrintSpace Altair desktop printer and used to create several test parts similar in quality to those created using a resistive heated nozzle.

  17. GCP 1.0: A Tool for Cost Management in Micro and Small Textile Manufacturing Companies in Bucaramanga

    Directory of Open Access Journals (Sweden)

    Ofelia Gómez Niño

    2015-11-01

    Full Text Available This article presents the results of a diagnostic study in which 52 textile manufacturing companies were observed in Bucaramanga to characterize the needs of these productive units. Based on the results, three strategic options were formulated to improve performance: a To consolidate the productive system by tools that facilitate production processes, b to strengthen cost structure by designing systems and tools; and c to share technological initiatives, knowledge and experience to improve resource management. From this perspective, the second phase of the research was oriented to develop the software GCP 1.0 for micro and small companies of children’s confection in Bucaramanga, a production cost information system that would facilitate cost management and the fixation of sale prices.

  18. Determination of the manufacturing cost by UEP method: a case study in the cold storage sausage making industry

    Directory of Open Access Journals (Sweden)

    Rodney Wernke

    2015-03-01

    Full Text Available This article aimed to answer the following research question: how to show the manager of a company that produces sausages’ the positive impacts of knowing the unit cost of processing? The objective was to verify the possibility of applying the UEP method to determine the cost of processing the products manufactured by a company of this type. A descriptive methodology was used in a case study format, with a qualitative approach. A literature review was initially conducted regarding the UEP method, approaching aspects such as history, concepts, guiding principles, steps to be taken for implementation, benefits and associated limitations. Then the main characteristics of the case study conducted through a brief description of the focused company and the steps followed to implement such a method of costing were presented. Subsequently, the informational benefits highlighted by the study and the limitations of methodology were listed . It was concluded that the method is applicable in the context of this company.

  19. Metal Additive Manufacturing: A Review

    Science.gov (United States)

    Frazier, William E.

    2014-06-01

    This paper reviews the state-of-the-art of an important, rapidly emerging, manufacturing technology that is alternatively called additive manufacturing (AM), direct digital manufacturing, free form fabrication, or 3D printing, etc. A broad contextual overview of metallic AM is provided. AM has the potential to revolutionize the global parts manufacturing and logistics landscape. It enables distributed manufacturing and the productions of parts-on-demand while offering the potential to reduce cost, energy consumption, and carbon footprint. This paper explores the material science, processes, and business consideration associated with achieving these performance gains. It is concluded that a paradigm shift is required in order to fully exploit AM potential.

  20. Traditional Technology and Cost-reduction As a Major Driver in Business: Can Outsourcing Relations be Redirected by Smart Manufacturing?

    NARCIS (Netherlands)

    Filippov, S.; Enserink, B.; Van Geenhuizen, M.S.; Berben, W.

    2012-01-01

    Traditional technologies can have an extended lifetime if companies use various cost-reducing strategies. One of these strategies employed in Western European countries in the past decades has been low-cost outsourcing in Central and Eastern Europe (CEE), mainly derived from low wages. Specifically,

  1. Traditional Technology and Cost-reduction As a Major Driver in Business: Can Outsourcing Relations be Redirected by Smart Manufacturing?

    NARCIS (Netherlands)

    Filippov, S.; Enserink, B.; Van Geenhuizen, M.S.; Berben, W.

    2012-01-01

    Traditional technologies can have an extended lifetime if companies use various cost-reducing strategies. One of these strategies employed in Western European countries in the past decades has been low-cost outsourcing in Central and Eastern Europe (CEE), mainly derived from low wages. Specifically,

  2. Modular Exhaust Design and Manufacturing Techniques for Low Cost Mid Volume Rapid Buidl to Order Systems

    Science.gov (United States)

    2014-08-06

    acoustic model into the give space claim. The current plan is to use parametric solid models generated from SolidWorks as the basis of the...manufacturing models. Parametric elements will be generated which are easily modifiable and easy to mate together. The SolidWorks API will then be used

  3. Final Rule to Reduce Toxic Air Emissions from Lime Manufacturing Plants Fact Sheet

    Science.gov (United States)

    This page contains an August 2003 fact sheet with information regarding the National Emissions Standards for Hazardous Air Pollutants (NESHAP) for Lime Manufacturing Plants. This document provides a summary of the information for this NESHAP.

  4. Reducing The Operating Costs Of An Apartment Building

    Directory of Open Access Journals (Sweden)

    Takács Ján

    2015-09-01

    Full Text Available Circulation pumps are mechanical devices, which are used to create the overpressure required for the transportation of a heat-transfer medium in heating technology as well as in other related technologies. In a circulation pump the mechanical energy generated by the drive machine – an electric motor is transformed to hydraulic energy, which consists of kinetic and static energy. In the pipeline of a heating system circulation pumps represent a source of hydraulic energy (positive differential pressure, which is consumed to transport the heat-transfer medium. During the flow, the heat-transfer medium puts up resistance to the so-called passive resistors, which consist of pressure losses from friction in the pipes and pressure losses due to local resistance. In this article the authors analyze the effect of a circulation pump on the operating costs in an apartment building. Different types of circulating pumps, ranging from the most unfavorable to the optimal, were selected.

  5. KANTARA: a Framework to Reduce ETL Cost and Complexity

    Directory of Open Access Journals (Sweden)

    Ahmed Kabiri

    2016-04-01

    Full Text Available Data warehouse (DW has been widely recognized as an effective solution for integrating diverse sources. In this environment, Extraction Transformation Loading (ETL processes constitute the integration layer. They perform data extraction, their cleaning, their conforming and loading into the target. It is widely recognized that building ETL processes, in a data warehouse project, are expensive regarding time and money. In spite of the abundance of works and proposals, around ETL, there is no proposal towards a global approach taking in account the cost and the complexity of ETL processes. In this context, we propose in this paper, a framework called KANTARA for managing ETL processes based on our experience in real world.

  6. Reducing The Operating Costs Of An Apartment Building

    Science.gov (United States)

    Takács, Ján; Rácz, Lukáš

    2015-09-01

    Circulation pumps are mechanical devices, which are used to create the overpressure required for the transportation of a heat-transfer medium in heating technology as well as in other related technologies. In a circulation pump the mechanical energy generated by the drive machine - an electric motor is transformed to hydraulic energy, which consists of kinetic and static energy. In the pipeline of a heating system circulation pumps represent a source of hydraulic energy (positive differential pressure), which is consumed to transport the heat-transfer medium. During the flow, the heat-transfer medium puts up resistance to the so-called passive resistors, which consist of pressure losses from friction in the pipes and pressure losses due to local resistance. In this article the authors analyze the effect of a circulation pump on the operating costs in an apartment building. Different types of circulating pumps, ranging from the most unfavorable to the optimal, were selected.

  7. Phase correlator reduces mm-wave radar cost

    Science.gov (United States)

    Weiss, R., Sr.; Hobbs, P.; Locatelli, J.

    1986-03-01

    A technique involving the IC storage of magnetron phase for reference has been developed to make possible the use of the low-cost efficient magnetron in obtaining phase coherent signals for pulse Doppler radar. In the new external coherence method, the recorded random midpulse-region phase is compared with the frequency of the echo allowing Doppler information, free of phase noise, to be extracted. The gated magnetron was tested at Ka-band in a 35-GHz radar, and good agreement with the CP-4 5.5 GHz radar was shown. With good accuracy down to 10 cm/s, the present system, especially in the mm-wave region, has important applications to meteorological and military radar.

  8. Leg exoskeleton reduces the metabolic cost of human hopping.

    Science.gov (United States)

    Grabowski, Alena M; Herr, Hugh M

    2009-09-01

    During bouncing gaits such as hopping and running, leg muscles generate force to enable elastic energy storage and return primarily from tendons and, thus, demand metabolic energy. In an effort to reduce metabolic demand, we designed two elastic leg exoskeletons that act in parallel with the wearer's legs; one exoskeleton consisted of a multiple leaf (MLE) and the other of a single leaf (SLE) set of fiberglass springs. We hypothesized that hoppers, hopping on both legs, would adjust their leg stiffness while wearing an exoskeleton so that the combination of the hopper and exoskeleton would behave as a linear spring-mass system with the same total stiffness as during normal hopping. We also hypothesized that decreased leg force generation while wearing an exoskeleton would reduce the metabolic power required for hopping. Nine subjects hopped in place at 2.0, 2.2, 2.4, and 2.6 Hz with and without an exoskeleton while we measured ground reaction forces, exoskeletal compression, and metabolic rates. While wearing an exoskeleton, hoppers adjusted their leg stiffness to maintain linear spring-mass mechanics and a total stiffness similar to normal hopping. Without accounting for the added weight of each exoskeleton, wearing the MLE reduced net metabolic power by an average of 6% and wearing the SLE reduced net metabolic power by an average of 24% compared with hopping normally at frequencies between 2.0 and 2.6 Hz. Thus, when hoppers used external parallel springs, they likely decreased the mechanical work performed by the legs and substantially reduced metabolic demand compared with hopping without wearing an exoskeleton.

  9. Integrated Glass Coating Manufacturing Line

    Energy Technology Data Exchange (ETDEWEB)

    Brophy, Brenor [Enki Technology Inc., San Jose, CA (United States)

    2015-09-30

    This project aims to enable US module manufacturers to coat glass with Enki’s state of the art tunable functionalized AR coatings at the lowest possible cost and highest possible performance by encapsulating Enki’s coating process in an integrated tool that facilitates effective process improvement through metrology and data analysis for greater quality and performance while reducing footprint, operating and capital costs. The Phase 1 objective was a fully designed manufacturing line, including fully specified equipment ready for issue of purchase requisitions; a detailed economic justification based on market prices at the end of Phase 1 and projected manufacturing costs and a detailed deployment plan for the equipment.

  10. Business Process Re-engineering: A Panacea for Reducing Operational Cost in Service Organizations

    Directory of Open Access Journals (Sweden)

    Joseph Joseph Sungau

    2015-03-01

    Full Text Available Organizations in today’s business environment struggle on how to reduce operation cost in order to set prices that can be afforded by many customers while obtaining reasonable profit.  In order to reduce Operational Cost, service organizations have been working hard to identify techniques that facilitate business processes improvement for reduced Operational Cost. In so doing, the global literature indicates that service organizations adopt Business Process Re-engineering technique as a panacea of reducing Operational Cost. Despite a documented potentiality of Business Process Re-engineering technique, there are mixed empirical results, findings and conclusions regarding the effect of Business Process Re-engineering on Operational Cost. Therefore, this paper aimed at assessing and explaining effects of BPR on Operational Cost.   The study used cross-sectional survey design to investigate the effect of BPR on Operational Cost. Intensive literature review enabled the construction of structural measurement model, formulation of testable hypotheses and operationalization of constructs. In order to test the model and hypotheses, data were collected from ninety five (95 service organizations in Tanzania. Results of the study reveal that BPR and delivering speed have no direct effects on Operational Cost; they indirectly affect Operational Cost through the mediations of service quality. Therefore, BPR influences first both service quality and delivery speed in affecting Operational Cost of service organizations. It is now recommended that service organizations should use Business Process Re-engineering as panacea of reducing Operational Cost.    

  11. Wide and High Additive Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Post, Brian K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Roschli, Alex C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-03-01

    The goal of this project is to develop and demonstrate the enabling technologies for Wide and High Additive Manufacturing (WHAM). WHAM will open up new areas of U.S. manufacturing for very large tooling in support of the transportation and energy industries, significantly reducing cost and lead time. As with Big Area Additive Manufacturing (BAAM), the initial focus is on the deposition of composite materials.

  12. Compliance to HIV treatment monitoring guidelines can reduce laboratory costs

    Directory of Open Access Journals (Sweden)

    Naseem Cassim

    2016-02-01

    Full Text Available Background: Panel tests are a predetermined group of tests commonly requested together to provide a comprehensive and conclusive diagnosis, for example, liver function test (LFT. South African HIV antiretroviral treatment (ART guidelines recommend individual tests for toxicity monitoring over panel tests. In 2008, the National Health Laboratory Services (NHLS request form was redesigned to list individual tests instead of panel tests and removed the ‘other tests’ box option to facilitate efficient ART laboratory monitoring.Objectives: This study aimed to demonstrate changes in laboratory expenditure, for individual and panel tests, for ART toxicity monitoring.Method: NHLS Corporate Data Warehouse (CDW data were extracted for HIV conditional grant accounts to assess ART toxicity monitoring laboratory expenditure between 2010/2011 and 2014/2015. Data were classified based on the tests requested, as either panel (LFT or urea and electrolytes or individual (alanine transaminase or creatinine tests.Results: Expenditure on panel tests reduced from R340 million in 2010/2011 to R140m by 2014/2015 (reduction of R204m and individual test expenditure increased from R34m to R76m (twofold increase. A significant reduction in LFT panel expenditure was noted, reducing from R322m in 2010/2011 to R130m in 2014/2015 (60% reduction.Conclusion: Changes in toxicity monitoring guidelines and the re-engineering of the NHLS request form successfully reduced expenditure on panel tests relative to individual tests. The introduction of order entry systems could further reduce unnecessary laboratory expenditure.Keywords: HIV;ART;Toxicity Monitoring;Expenditure

  13. Soil Segregation Methods for Reducing Transportation and Disposal Costs - 13544

    Energy Technology Data Exchange (ETDEWEB)

    Frothingham, David; Andrews, Shawn; Barker, Michelle; Boyle, James; Buechi, Stephen; Graham, Marc; Houston, Linda; Polek, Michael; Simmington, Robert; Spector, Harold [U.S. Army Corps of Engineers, Buffalo District, 1776 Niagara St., Buffalo, NY 14207 (United States); Elliott, Robert ' Dan' [U.S. Army Reserve, 812A Franklin St.,Worcester, MA 01604 (United States); Durham, Lisa [Argonne National Laboratory, Environmental Science Division, 9700 S. Cass Ave., Argonne, IL 60439 (United States)

    2013-07-01

    At Formerly Utilized Sites Remedial Action Program (FUSRAP) sites where the selected alternative for contaminated soil is excavation and off-site disposal, the most significant budget items of the remedial action are the costs for transportation and disposal of soil at an off-site facility. At these sites, the objective is to excavate and dispose of only those soils that exceed derived concentration guideline levels. In situ soil segregation using gross gamma detectors to guide the excavation is often challenging at sites where the soil contamination is overlain by clean soil or where the contaminated soil is located in isolated, subsurface pockets. In addition, data gaps are often identified during the alternative evaluation and selection process, resulting in increased uncertainty in the extent of subsurface contamination. In response, the U.S. Army Corps of Engineers, Buffalo District is implementing ex situ soil segregation methods. At the remediated Painesville Site, soils were excavated and fed through a conveyor-belt system, which automatically segregated them into above- and below-cleanup criteria discharge piles utilizing gamma spectroscopy. At the Linde Site and the Shallow Land Disposal Area (SLDA) Site, which are both in the remediation phase, soils are initially segregated during the excavation process using gross gamma detectors and then transported to a pad for confirmatory manual surveying and sampling. At the Linde Site, the ex situ soils are analyzed on the basis of a site-specific method, to establish compliance with beneficial reuse criteria that were developed for the Linde remediation. At the SLDA Site, the ex situ soils are surveyed and sampled based on Multi-Agency Radiation Survey and Site Investigation Manual (MARSSIM) final status survey guidance to demonstrate compliance with the derived concentration guideline levels. At all three sites, the ex situ soils that meet the site- specific DCGLs are retained on-site and used as backfill

  14. Nisin Production Utilizing Skimmed Milk Aiming to Reduce Process Cost

    Science.gov (United States)

    Jozala, Angela Faustino; de Andrade, Maura Sayuri; de Arauz, Luciana Juncioni; Pessoa, Adalberto; Penna, Thereza Christina Vessoni

    Nisin is a natural additive for conservation of food, pharmaceutical, and dental products and can be used as a therapeutic agent. Nisin inhibits the outgrowth of spores, the growth of a variety of Gram-positive and Gram-negative bacteria. This study was performed to optimize large-scale nisin production in skimmed milk and subproducts aiming at low-costs process and stimulating its utilization. Lactococcus lactis American Type Culture Collection (ATCC) 11454 was developed in a rotary shaker (30°C/36 h/100 rpm) in diluted skimmed milk and nisin activity, growth parameters, and media components were also studied. Nisin activity in growth media was expressed in arbitrary units (AU/mL) and converted to standard nisin concentration (Nisaplin®, 25 mg of pure nisin is 1.0×106 AU/mL). Nisin activity in skimmed milk 2.27 gtotal solids was up to threefold higher than transfers in skimmed milk 4.54 gtotal solids and was up to 85-fold higher than transfers in skimmed milk 1.14 gtotal solids. L. lactis was assayed in a New Brunswick fermentor with 1.5 L of diluted skimmed milk (2.27 gtotal solids) and airflow of 1.5 mL/min (30°C/36/200 rpm), without pH control. In this condition nisin activity was observed after 4 h (45.07 AU/mL) and in the end of 36 h process (3312.07 AU/mL). This work shows the utilization of a low-cost growth medium (diluted skimmed milk) to nisin production with wide applications. Furthermore, milk subproducts (milk whey) can be exploited in nisin production, because in Brazil 50% of milk whey is disposed with no treatment in rivers and because of high organic matter concentrations it is considered an important pollutant. In this particular case an optimized production of an antimicrobial would be lined up with industrial disposal recycling.

  15. Large-scale Manufacturing of Nanoparticulate-based Lubrication Additives for Improved Energy Efficiency and Reduced Emissions

    Energy Technology Data Exchange (ETDEWEB)

    Erdemir, Ali [Argonne National Laboratory

    2013-09-26

    and environmental objectives of DOE and our nation. In this project, most of the boron-based materials with known and potential anti-friction and -wear properties have been manufactured as colloidal additives and tested for their effectiveness in controlling friction and wear. Unlike other anti-friction and -wear additives, which consist of zinc, molybdenum, sulfur, phosphorus, and even chlorine, lubricious boron compounds considered in this project are made of boron, oxygen, nitrogen, and hydrogen, which are more environmentally benign. Among others, boric acid is a natural mineral (known in mineralogy as "sassolite"). Based on our earlier exploratory research, it was found to offer the best overall prospect in terms of performance improvements, environmental friendliness, and ease of manufacturing and, hence, cost effectiveness. Hexagonal boron nitride and borax also offered good prospects for improving the tribological properties of lubricated sliding surfaces. Boron oxide particles were found to be rather hard and somewhat abrasive and, hence, were not considered beyond the initial screening studies. In our bench-top tribological evaluation, we also demonstrated that those additives which worked well with engine oils could work equally well with very common gear oils. When added at appropriate concentrations, such gear oils were found to provide significant resistance to micropitting and scuffing failures in bench-top tribological test systems. Their traction coefficients were also reduced substantially and their scuffing limits were improved considerably. Such impressive tribological behavior of boron-based additives may have been due to their high chemical affinities to interact with sliding contact surfaces and to form slick and protective boundary films. Indeed, our surface studies have confirmed that most of the boron-based nanoparticulate additives prepared in our project possess a strong tendency to form a boron-rich boundary film on sliding contact

  16. Low-Cost Nanocellulose-Reinforced High-Temperature Polymer Composites for Additive Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Ozcan, Soydan [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Tekinalp, Halil L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Love, Lonnie J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Kunc, Vlastimil [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Nelson, Kim [American Process Inc., Atlanta, GA (United States)

    2016-07-13

    ORNL worked with American Process Inc. to demonstrate the potential use of bio-based BioPlus® lignin-coated cellulose nanofibrils (L-CNF) as a reinforcing agent in the development of polymer feedstock suitable for additive manufacturing. L-CNF-reinforced polylactic acid (PLA) testing coupons were prepared and up to 69% increase in tensile strength and 133% increase in elastic modulus were demonstrated.

  17. Manufacturing Techniques for Producing High Quality Fluidic Laminates at Low Cost.

    Science.gov (United States)

    1980-09-02

    1473 EDITION OF INOV GS OOETE UNCLASSIFIED SECURITY CLASSIFICATION OF THIS PAGE IP.I1 *I@ %.#* " t UNCLASSIFIED SECURITY CLASIIrCATION OF THIS PAGI[(Wm...metal not protected by the photo-resist material to create the fluidic laminate. 1 Photochemical etching is the process used extensively in the...electronic industry for printed circuit board manufacture. This process involves coating the sur- face of the material to be etched with a photo-sensitive

  18. Low-cost Design and Manufacturing of Surgical Guides for Mandibular Reconstruction Using a Fibula

    OpenAIRE

    2016-01-01

    Background: Surgical cutting guides are used in mandibular reconstruction involving osteotomy of the mandible and fibula. Cutting guides produced using computer-aided design (CAD) and computer-aided manufacturing (CAM) technologies have been reported recently. These guides aim to increase the benefits to patients by improving the accuracy, shortening the operating time, and correcting occlusion. However, the availability of these advanced technologies is limited in some regions of the world. ...

  19. Reducing Memory Cost of Exact Diagonalization using Singular Value Decomposition

    Energy Technology Data Exchange (ETDEWEB)

    Weinstein, Marvin; /SLAC; Auerbach, Assa; /Stanford U., Phys. Dept. /Technion; Chandra, V.Ravi; /Technion

    2011-11-04

    We present a modified Lanczos algorithm to diagonalize lattice Hamiltonians with dramatically reduced memory requirements. The lattice of size N is partitioned into two subclusters. At each iteration the Lanczos vector is projected into a set of n{sub svd} smaller subcluster vectors using singular value decomposition. For low entanglement entropy S{sub ee}, (satisfied by short range Hamiltonians), we expect the truncation error to vanish as exp(-n{sup 1/S{sub ee}}{sub svd}). Convergence is tested for the Heisenberg model on Kagome clusters of up to 36 sites, with no symmetries exploited, using less than 15GB of memory. Generalization to multiple partitioning is discussed.

  20. Monitor energy consumption - Reduce costs; Energieverbrauch ueberwachen - Kosten senken

    Energy Technology Data Exchange (ETDEWEB)

    Bolliger, R.

    2008-07-01

    This article takes a look at energy consumption in residential, industrial and commercial buildings and how energy consumption metering can help reduce energy consumption. The proprietary system briefly described uses the KNX bus system to transfer data. Visualisation of the data collected is briefly described. Peak-load management and ways of adapting user behaviour are discussed. Trends towards higher levels of consumption - particularly in emerging markets - are discussed. Energy needs, carbon dioxide emissions, investments and potentials for making savings are discussed. Possibilities of increasing energy efficiency in the residential, industrial and commercial sectors are examined.

  1. Toward a new spacecraft optimal design lifetime? Impact of marginal cost of durability and reduced launch price

    Science.gov (United States)

    Snelgrove, Kailah B.; Saleh, Joseph Homer

    2016-10-01

    The average design lifetime of satellites continues to increase, in part due to the expectation that the satellite cost per operational day decreases monotonically with increased design lifetime. In this work, we challenge this expectation by revisiting the durability choice problem for spacecraft in the face of reduced launch price and under various cost of durability models. We first provide a brief overview of the economic thought on durability and highlight its limitations as they pertain to our problem (e.g., the assumption of zero marginal cost of durability). We then investigate the merging influence of spacecraft cost of durability and launch price, and we identify conditions that give rise cost-optimal design lifetimes that are shorter than the longest lifetime technically achievable. For example, we find that high costs of durability favor short design lifetimes, and that under these conditions the optimal choice is relatively robust to reduction in launch prices. By contrast, lower costs of durability favor longer design lifetimes, and the optimal choice is highly sensitive to reduction in launch price. In both cases, reduction in launch prices translates into reduction of the optimal design lifetime. Our results identify a number of situations for which satellite operators would be better served by spacecraft with shorter design lifetimes. Beyond cost issues and repeat purchases, other implications of long design lifetime include the increased risk of technological slowdown given the lower frequency of purchases and technology refresh, and the increased risk for satellite operators that the spacecraft will be technologically obsolete before the end of its life (with the corollary of loss of value and competitive advantage). We conclude with the recommendation that, should pressure to extend spacecraft design lifetime continue, satellite manufacturers should explore opportunities to lease their spacecraft to operators, or to take a stake in the ownership

  2. Low Cost Automated Manufacture of PV Array Technology (P-NASA12-007-1) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Spacecraft for NASA, DoD and commercial missions need higher power than ever before, with lower mass, compact stowage, and lower cost. While high efficiency,...

  3. Manufacture and sensory analysis of reduced- and low-sodium Cheddar and Mozzarella cheeses.

    Science.gov (United States)

    Ganesan, Balasubramanian; Brown, Kelly; Irish, David A; Brothersen, Carl; McMahon, Donald J

    2014-01-01

    High sodium intake negatively affects consumer health, thus there is active interest in lowering sodium levels in dairy foods. Cheddar and low-moisture, part-skim Mozzarella cheeses were made with total salt levels of 0.7, 1.0, 1.25, 1.35, and 1.8% (wt/wt) in triplicate, thus reducing sodium by 25 to 60%. Multiple manufacturing protocols for salt reduction were used to produce cheeses with similar postpress moisture and pH, independent of the final salt levels in cheese, in order to study the role of salt in cheese acceptability. Cheese flavor was evaluated by a descriptive taste panel on a 15-point intensity scale. Consumer acceptance was evaluated by a consumer panel on a 9-point hedonic scale. Taste panels conducted with cubed Cheddar cheese (at 3 and 6mo) and cold shredded Mozzarella cheese (at 3wk) showed that consumer liking for cheese was low at 0.7 and 0.9% salt, but all cheeses containing higher salt levels (1.25, 1.35, and 1.8% salt) were comparably preferred. The cheeses had acceptable liking scores (≥6) when served as quesadilla or pizza toppings, and consumers were able to differentiate cheeses at alternate salt levels; for example, 1.8 and 1.5% salt cheeses scored similarly, as did cheeses with 1.5% and 1.35% salt, but 1.35% salt cheese scored lower than and was discernible from 1.8% salt cheese. Descriptive panelists perceived salty, sour, umami, bitter, brothy, lactone/fatty acid, and sulfur attributes as different across Mozzarella cheeses, with the perception of each significantly increasing along with salt level. Salty and buttery attributes were perceived more with increasing salt levels of Cheddar cheese by the descriptive panel at 3mo, whereas bitter, brothy, and umami attributes were perceived less at the higher salt levels. However, this trend reversed at 6mo, when perception of salty, sour, bitter, buttery, lactone/fatty acid, and umami attributes increased with salt level. We conclude that consumers can distinguish even a 30% salt

  4. Implementation of Lean Manufacturing System for Successful Production System in Manufacturing Industries

    Directory of Open Access Journals (Sweden)

    Mohd Shoeb

    2017-06-01

    Full Text Available In manufacturing industries lean manufacturing is a broadly accepted philosophy. There are more requirements of research and studies. To investigate the needs, techniques, benefits of lean manufacturing and approaches for implementation Lean manufacturing is a leading manufacturing paradigm has applied in many economy sectors, where we have to reduce manufacturing cost, improving product quality, reducing cost of poor quality, and quick to respond and “first to market to customer needs are critical to competitiveness and success. Lean methods and principle focus on the continuous improvement and engages employees reducing the intensity of materials, time, and capital necessary for meeting a customer’s needs. Successful implementation of lean manufacturing is very important to increase quality and waste reduction. By implementation of lean manufacturing there are various benefits such as waste elimination, reduction in reworking, financial benefits, lead time reduction and lower inventory levels.

  5. Development of a fixed abrasive slicing technique (FAST) for reducing the cost of photovoltaic wafers

    Energy Technology Data Exchange (ETDEWEB)

    Schmid, F. (Crystal Systems, Inc., Salem, MA (United States))

    1991-12-01

    This report examines a wafer slicing technique developed by Crystal Systems, Inc. that reduces the cost of photovoltaic wafers. This fixed, abrasive slicing technique (FAST) uses a multiwire bladepack and a diamond-plated wirepack; water is the coolant. FAST is in the prototype production stage and reduces expendable material costs while retaining the advantages of a multiwire slurry technique. The cost analysis revealed that costs can be decreased by making more cuts per bladepack and slicing more wafers per linear inch. Researchers studied the degradation of bladepacks and increased wirepack life. 21 refs.

  6. PENDEKATAN ACTIVITY-BASED COSTING DAN METODE PENCARIAN HEURISTIC UNTUK MENYELESAIKAN PROBLEM PEMILIHAN PERALATAN PADA FLEXIBLE MANUFACTURING SYSTEMS (FMS

    Directory of Open Access Journals (Sweden)

    Gregorius Satia Budhi

    2002-01-01

    Full Text Available The application of Activity Based Costing (ABC approach to select the set-machine that is used in the production of Flexible Manufacture System (FMS based on technical and economical criteria can be useful for producers to design FMS by considering the minimum production cost. In the other hand, Heuristic Search is known to have a short searching time. Algorithm Heuristic that using ABC approach as the weight in finding the solution to shorten the equipment selection time during the design / redesign process of the FMS in less than exponential time was designed in this research. The increasing speed is useful because with the faster time in design / redesign process, therefore the flexibility level of part variety that can be processed will become better. Theoretical and empirical analysis in Algorithm Heuristic shows that time searching to get appropriate set of equipment is not too long, so that we can assume that the designed Algorithm Heuristic can be implemented in the real world. By comparing the empirical result of Algorithm Heuristic to the Algorithm Exhaustive, we can also assume that Algorithm Heuristic that using ABC method as the weight for finding solution can optimise the equipment selection problem of FMS based on economical criteria too. Abstract in Bahasa Indonesia : Penggunaan pendekatan Activity Based Costing (ABC untuk memilih set mesin yang digunakan dalam produksi pada Flexible Manufacture Systems (FMS berdasar atas kriteria teknis dan ekonomis, dapat membantu pelaku produksi untuk mendisain FMS dengan pertimbangan minimalisasi biaya produksi. Sementara itu, Heuristic Search dikenal memiliki waktu pencarian yang singkat. Pada riset ini didisain sebuah Algoritma Heuristic yang menggunakan pendekatan ABC sebagai bobot dalam pencarian solusi, untuk mempersingkat waktu pemilihan peralatan saat desain/redisain FMS dalam waktu kurang dari waktu Eksponensial. Peningkatan kecepatan ini bermanfaat, karena dengan cepatnya waktu

  7. Final Regulations to Reduce Toxic Air Pollutant Emissions from Brick and Structural Clay Products Manufacturing and Clay Ceramics Manufacturing Fact Sheets

    Science.gov (United States)

    This page contains a February 2003 and September 2015 fact sheet with information regarding the final rules to the NESHAP for Brick and Structural Clay Products Manufacturing and the NESHAP for Clay Ceramics Manufacturing

  8. Manufacturing Cost/Design Guide (MC/DG) for Aerospace Applications.

    Science.gov (United States)

    1988-05-02

    prevent removal without distortion if driven into the impression while the metal was hot. Underfill : The portion of a forging which does not have its...monitoring) - Laminate (quality/ voids /porosity). 3.4 Diffusion bonding e Complexity e Size -Available equipment capacity -Support tooling * Equipment costs a

  9. Costs of a Staff Communication Intervention to Reduce Dementia Behaviors in Nursing Home Care.

    Science.gov (United States)

    Williams, Kristine N; Ayyagari, Padmaja; Perkhounkova, Yelena; Bott, Marjorie J; Herman, Ruth; Bossen, Ann

    2017-01-01

    Persons with Alzheimer's disease and other dementias experience behavioral symptoms that frequently result in nursing home (NH) placement. Managing behavioral symptoms in the NH increases staff time required to complete care, and adds to staff stress and turnover, with estimated cost increases of 30%. The Changing Talk to Reduce Resistivenes to Dementia Care (CHAT) study found that an intervention that improved staff communication by reducing elderspeak led to reduced behavioral symptoms of dementia or resistiveness to care (RTC). This analysis evaluates the cost-effectiveness of the CHAT intervention to reduce elderspeak communication by staff and RTC behaviors of NH residents with dementia. Costs to provide the intervention were determined in eleven NHs that participated in the CHAT study during 2011-2013 using process-based costing. Each NH provided data on staff wages for the quarter before and for two quarters after the CHAT intervention. An incremental cost-effectiveness analysis was completed. An average cost per participant was calculated based on the number and type of staff attending the CHAT training, plus materials and interventionist time. Regression estimates from the parent study then were applied to determine costs per unit reduction in staff elderspeak communication and resident RTC. A one percentage point reduction in elderspeak costs $6.75 per staff member with average baseline elderspeak usage. Assuming that each staff cares for 2 residents with RTC, a one percentage point reduction in RTC costs $4.31 per resident using average baseline RTC. Costs to reduce elderspeak and RTC depend on baseline levels of elderspeak and RTC, as well as the number of staff participating in CHAT training and numbers of residents with dementia-related behaviors. Overall, the 3-session CHAT training program is a cost-effective intervention for reducing RTC behaviors in dementia care.

  10. UHF electromagnetic structures inkjet printed on temperature sensitive substrates: A comparative study of conductive inks and sintering methods to enable low cost manufacture

    NARCIS (Netherlands)

    Sanchez-Romaauera, V.; Wünscher, S.; Abbel, R.J.; Zial, M.A.; Oyeka, D.; Turki, B.M.M.; Batchelor, J.C.; Parker, E.A.; Schubert, U.S.; Yeates, S.G.

    2013-01-01

    In this paper we demonstrate the use of inkjet printing as a facile digital fabrication tool for the cost effective manufacture of UHF RFID transfer tattoo tags and Frequency Selective Surfaces on low-cost flexible and porous substrates. Electrical and morphological properties of conductive features

  11. UHF electromagnetic structures inkjet printed on temperature sensitive substrates: A comparative study of conductive inks and sintering methods to enable low cost manufacture

    NARCIS (Netherlands)

    Sanchez-Romaauera, V.; Wünscher, S.; Abbel, R.J.; Zial, M.A.; Oyeka, D.; Turki, B.M.M.; Batchelor, J.C.; Parker, E.A.; Schubert, U.S.; Yeates, S.G.

    2013-01-01

    In this paper we demonstrate the use of inkjet printing as a facile digital fabrication tool for the cost effective manufacture of UHF RFID transfer tattoo tags and Frequency Selective Surfaces on low-cost flexible and porous substrates. Electrical and morphological properties of conductive features

  12. Evaluation of Fermented Sausages Manufactured with Reduced-fat and Functional Starter Cultures on Physicochemical, Functional and Flavor Characteristics.

    Science.gov (United States)

    Kim, Young Joo; Park, Sung Yong; Lee, Hong Cheol; Yoo, Seung Seok; Oh, Se Jong; Kim, Hyeong Sang; Chin, Koo Bok

    2014-01-01

    Fermented foods with probiotics having functional properties may provide beneficial effects on health. These effects are varied, depending on the type of lactic acid bacteria (LAB). Different probiotic LAB might have different functional properties. Thus, this study was performed to evaluate the quality of fermented sausages manufactured with functional starter cultures (Lactobacillus plantarum 115 and 167, and Pediococcus damnosus L12) and different fat levels, and to determine the optimum condition for the manufacture of these products. Medium-fat (~15%) fermented sausages reduced the drying time and cholesterol contents, as compared to regular-fat counterparts. In proximate analysis, the contents of moisture and protein of regular-fat products were lower than medium-fat with reduced fat content. The regular-fat products also had a lighter color and less redness, due to reduced fat content. Approximately 35 volatile compounds were identified in functional fermented sausages, and hexanal, trans-caryophyllene, and tetradecanal were the major volatile compounds. Selected mixed starter culture showed the potential possibility of replacing the commercial starter culture (LK30 plus) in flavor profiles. However, medium-fat fermented sausage containing selected mixed starter culture tended to be less acceptable than their high-fat counterparts, due to excess dry ring developed in the surface. These results indicate that the use of combinations of L. plantarum 115 and 167, and P. damnosus L12 as a starter culture, will prove useful for manufacturing the fermented sausage.

  13. China’s Three Giants in Air Conditioner Manufacturing Reduced Production to Cut Excessive Inventory

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>Midea,Haier and Gree,China’s three giants in air conditioner manufacturing who have been troubled by an excessive inventory due to a cool summer this year,have cut their produc- tions,marking a premature end to the huge de- mand in China’s air conditioner market lasting for three consecutive years.Currently the whole industry has an inventory of more than 10 million air conditioners.

  14. Highly Conformal Ni Micromesh as a Current Collecting Front Electrode for Reduced Cost Si Solar Cell.

    Science.gov (United States)

    Gupta, Nikita; Rao, K D Mallikharjuna; Gupta, Ritu; Krebs, Frederik C; Kulkarni, Giridhar U

    2017-02-17

    Despite relatively high manufacturing cost, crystalline-Si solar cell continues to hold promising future due to its high energy conversion efficiency and long life. As regards cost, one pertinent issue is the top electrode metallization of textured cell surface, which typically involves screen printing of silver paste. The associated disadvantages call for alternative methods that can lower the cost without compromising the solar cell efficiency. In the present work, a highly interconnected one dimensional (1D) metal wire network has been employed as front electrode on conventional Si wafers. Here for the first time, we report an innovative solution based crackle templating method for conformal metal wire network patterning over large textured surfaces. Laser beam induced current mapping showed uniform photocurrent collection by the electrodes without any shadow losses. With electroless deposition of Ni wire network on corrugated solar cell, a short circuit current of 33.28 mA/cm2 was obtained in comparison to 20.53 mA/cm2 without the network electrode. On comparing the efficiency with the conventional cells with screen printed electrodes, a 20% increment in efficiency has been observed. Importantly, the estimated manufacturing cost is three orders lower.

  15. The model for the calculation of the dispersed iron ore resource purchase cost in the world class manufacturing (WCM logistics pillar context

    Directory of Open Access Journals (Sweden)

    M. Dudek

    2014-10-01

    Full Text Available In the blast-furnace production, raw materials may account for approx. 50 % of the pig-iron manufacture costs. Therefore, any, even small, saving in the sphere of raw material purchasing will translate into the reduction in the cost of the pig-iron manufacture. The selection of appropriate supply sources and the associated raw material quality influencing the economic viability of the charge blend constitutes a multi-faceted optimization task. The paper presents a modified model for production cost estimation at the moment of making raw material purchasing, which is possible to be used in the logistics pillar of the WCM concept.

  16. Cost-effective manufacturing of compact TDLAS sensors for hazardous area applications

    Science.gov (United States)

    Frish, Michael B.; Laderer, Mathew C.; Smith, Clinton J.; Ehid, Ryan; Dallas, Joseph

    2016-03-01

    Tunable Diode Laser Absorption Spectroscopy (TDLAS) is finding ever increasing utility for industrial process measurement and control. The technique's sensitivity and selectivity benefit continuous concentration measurements of specific gas components in complex gas mixtures which are often laden with liquids or solid particulates. Tradeoff options among optical path length, absorption linestrength, linewidth, cross-interferences, and sampling methodology enable sensor designers to optimize detection for specific applications. Emerging applications are demanding increasing numbers of distributed miniaturized sensors at diminishing costs. In these applications, the TDLAS specificity is a key attribute, and its high sensitivity enables novel sampling package designs with short optical path lengths. This paper describes a miniature hermetically-sealed backscatter TDLAS transceiver package designed for high-volume production at acceptable cost. Occupying a volume less than 1in3 and weighing less than 0.06 lb, the transceiver is a key component of TDLAS sensors intended for in-situ measurements of potentially explosive gas mixtures.

  17. Manufacture of patient-specific vascular replicas for endovascular simulation using fast, low-cost method

    Science.gov (United States)

    Kaneko, Naoki; Mashiko, Toshihiro; Ohnishi, Taihei; Ohta, Makoto; Namba, Katsunari; Watanabe, Eiju; Kawai, Kensuke

    2016-12-01

    Patient-specific vascular replicas are essential to the simulation of endovascular treatment or for vascular research. The inside of silicone replica is required to be smooth for manipulating interventional devices without resistance. In this report, we demonstrate the fabrication of patient-specific silicone vessels with a low-cost desktop 3D printer. We show that the surface of an acrylonitrile butadiene styrene (ABS) model printed by the 3D printer can be smoothed by a single dipping in ABS solvent in a time-dependent manner, where a short dip has less effect on the shape of the model. The vascular mold is coated with transparent silicone and then the ABS mold is dissolved after the silicone is cured. Interventional devices can pass through the inside of the smoothed silicone vessel with lower pushing force compared to the vessel without smoothing. The material cost and time required to fabricate the silicone vessel is about USD $2 and 24 h, which is much lower than the current fabrication methods. This fast and low-cost method offers the possibility of testing strategies before attempting particularly difficult cases, while improving the training of endovascular therapy, enabling the trialing of new devices, and broadening the scope of vascular research.

  18. Some Solution Approaches to Reduce the Imbalance of Workload in Parallel Machines while Planning in Flexible Manufacturing System

    Directory of Open Access Journals (Sweden)

    B.V.Raghavendra,

    2010-05-01

    Full Text Available The loading problem in a Flexible Manufacturing System (FMS is viewed as selecting a subset of jobs from a job pool and allocating the jobs among the machines. Balancing the workload on the parallel machines will reduce the bottleneck and improve the utilization of the machine tools. In this paper an effort is made for developing thestrategies in the pre-release / planning stage which will reduce the imbalance between the parallel machines. Two different strategies are developed and the traditional sequencing shortest and longest rocessing time rule is applied to determine the relative performance index. An illustrative example is accompanies with the shortest processing time.

  19. Cost of unneeded proteins in E. coli is reduced after several generations in exponential growth.

    Science.gov (United States)

    Shachrai, Irit; Zaslaver, Alon; Alon, Uri; Dekel, Erez

    2010-06-11

    When E. coli cells express unneeded protein, they grow more slowly. Such penalty to fitness associated with making proteins is called protein cost. Protein cost is an important component in the cost-benefit tradeoffs that underlie the evolution of protein circuits, but its origins are still poorly understood. Here, we ask how the protein cost varies during the exponential growth phase of E. coli. We find that cells growing exponentially following an upshift from overnight culture show a large cost when producing unneeded proteins. However, after several generations, while still in exponential growth, the cells enter a phase where cost is much reduced despite vigorous unneeded protein production. We find that this reduced-cost phase depends on the ppGpp system, which adjusts the amount of ribosomes in the cell and does not occur after a downshift from rich to poor medium. These findings suggest that protein cost is a transient phenomenon that happens upon an upshift in conditions and that cost is reduced when ribosomes and other cellular systems have increased to their appropriate steady-state level in the new condition.

  20. Does probability guided hysteroscopy reduce costs in women investigated for postmenopausal bleeding?

    NARCIS (Netherlands)

    Breijer, M C; van Hanegem, N; Visser, N C M; Verheijen, R H M; Mol, B W J; Pijnenborg, J M A; Opmeer, B C; Timmermans, A

    2015-01-01

    OBJECTIVE: To evaluate whether a model to predict a failed endometrial biopsy in women with postmenopausal bleeding (PMB) and a thickened endometrium can reduce costs without compromising diagnostic accuracy. DESIGN, SETTING, AND POPULATION: Model based cost-minimization analysis. METHODS: A decisio

  1. Reducing Enzyme Costs Increases the Market Potential of Biofuels (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2013-08-01

    Cellulosic ethanol prices depend heavily on the cost of the cellulase enzymes used to break down the biomass into fermentable sugars. To reduce these costs, NREL partnered with two leading enzyme companies, Novozymes and Genencor, to engineer new cellulase enzymes that are exceptionally good at breaking down cellulose. Genencor is now part of DuPont Industrial Biosciences.

  2. Reducing Enzyme Costs Increases the Market Potential of Biofuels (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2013-08-01

    Cellulosic ethanol prices depend heavily on the cost of the cellulase enzymes used to break down the biomass into fermentable sugars. To reduce these costs, NREL partnered with two leading enzyme companies, Novozymes and Genencor, to engineer new cellulase enzymes that are exceptionally good at breaking down cellulose. Genencor is now part of DuPont Industrial Biosciences.

  3. Development of technology for thin substrate polycrystalline solar cells for practical use. Development of manufacturing technologies for low-cost substrates (low-cost Si sheets by continuous casting method); Usugata takessho taiyo denchi seizo gijutsu no jitsuyoka kenkyu. Tei cost kiban seizo gijutsu kaihatsu (renzoku cast ho ni yoru tei cost Si kiban seizo gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    Tatsuta, M. [New Energy and Industrial Technology Development Organization, Tokyo (Japan)

    1994-12-01

    This paper reports the study results on manufacturing of low-cost Si substrates by continuous casting method in fiscal 1994. (1) On manufacturing of ingots of 16 piece size, the ingot of nearly 170kg was manufactured by batch process using the Si melt injection unit prepared in last year. (2) On oxygen and carbon contents in wafers, the contents were measured by FT-IR after slicing of the ingot. As a result, the oxygen and carbon contents could be successfully reduced to the targets of 10ppma and 5ppma or less, respectively. (3) The resistivity distribution of the ingot ranged over the target of 1-2ohm-cm. (4) Cells of 100 {times} 100mm{sup 2} wide and 350{mu}m thick were verified by in-house evaluation process. Although lower cell conversion efficiency was found at the center top of the ingot, a vertical efficiency stability was nearly sufficient as a whole. (5) On the crystal growth unit prepared in fiscal 1994, any problems were not found on automatic driving and vibration during moving. 8 figs.

  4. Make or buy analysis model based on tolerance allocation to minimize manufacturing cost and fuzzy quality loss

    Science.gov (United States)

    Rosyidi, C. N.; Puspitoingrum, W.; Jauhari, W. A.; Suhardi, B.; Hamada, K.

    2016-02-01

    The specification of tolerances has a significant impact on the quality of product and final production cost. The company should carefully pay attention to the component or product tolerance so they can produce a good quality product at the lowest cost. Tolerance allocation has been widely used to solve problem in selecting particular process or supplier. But before merely getting into the selection process, the company must first make a plan to analyse whether the component must be made in house (make), to be purchased from a supplier (buy), or used the combination of both. This paper discusses an optimization model of process and supplier selection in order to minimize the manufacturing costs and the fuzzy quality loss. This model can also be used to determine the allocation of components to the selected processes or suppliers. Tolerance, process capability and production capacity are three important constraints that affect the decision. Fuzzy quality loss function is used in this paper to describe the semantic of the quality, in which the product quality level is divided into several grades. The implementation of the proposed model has been demonstrated by solving a numerical example problem that used a simple assembly product which consists of three components. The metaheuristic approach were implemented to OptQuest software from Oracle Crystal Ball in order to obtain the optimal solution of the numerical example.

  5. The source of investment cash flow sensitivity in manufacturing firms: Is it asymmetric information or agency costs?

    Directory of Open Access Journals (Sweden)

    Daniel Makina

    2016-09-01

    Full Text Available In the literature, positive investment cash flow sensitivity is attributed to either asymmetric information induced financing constraints or the agency costs of free cash flow. Using data from a sample of 68 manufacturing firms listed on the South African JSE, this paper contributes to the literature by investigating the source of investment cash flow sensitivity. We have found that asymmetric information explains the positive investment cash flow sensitivity better than agency costs. Furthermore, asymmetric information has been observed to be more pronounced in low-dividend-paying firms and small firms. Despite South Africa’s having a developed financial system by international standards, small firms are seen to be financially constrained. We attribute the absence of investment cash flow sensitivity due to agency costs to good corporate governance of South African listed firms. Thus the paper provides further evidence in support of the proposition in the literature that the source of investment cash flow sensitivity may depend on the institutional setting of a country, such as its corporate governance.

  6. Implementation of Lean System on Erbium Doped Fibre Amplifier Manufacturing Process to Reduce Production Time

    Science.gov (United States)

    Maneechote, T.; Luangpaiboon, P.

    2010-10-01

    A manufacturing process of erbium doped fibre amplifiers is complicated. It needs to meet the customers' requirements under a present economic status that products need to be shipped to customers as soon as possible after purchasing orders. This research aims to study and improve processes and production lines of erbium doped fibre amplifiers using lean manufacturing systems via an application of computer simulation. Three scenarios of lean tooled box systems are selected via the expert system. Firstly, the production schedule based on shipment date is combined with a first in first out control system. The second scenario focuses on a designed flow process plant layout. Finally, the previous flow process plant layout combines with production schedule based on shipment date including the first in first out control systems. The computer simulation with the limited data via an expected value is used to observe the performance of all scenarios. The most preferable resulted lean tooled box systems from a computer simulation are selected to implement in the real process of a production of erbium doped fibre amplifiers. A comparison is carried out to determine the actual performance measures via an analysis of variance of the response or the production time per unit achieved in each scenario. The goodness of an adequacy of the linear statistical model via experimental errors or residuals is also performed to check the normality, constant variance and independence of the residuals. The results show that a hybrid scenario of lean manufacturing system with the first in first out control and flow process plant lay out statistically leads to better performance in terms of the mean and variance of production times.

  7. SmartFactory: The challenges of open and low cost ICT in the small manufacturing industry

    CSIR Research Space (South Africa)

    Bosscha, PA

    2006-07-01

    Full Text Available , four high-speed counter inputs and eight high-current outputs (relays). The embedded PC caters for the wireless interface, memory and FreeBSD operating system, with attendant ease of higher level scripting and programming. The HMI is a serially... of failure of the primary central server. In such an event, the open nature of the x86 PC standard allows for cost-effective maintenance and support from various service and component suppliers. G. PostgreSQL The historian functionality is important...

  8. Reducing heliostat field costs by direct measurement and control of the mirror orientation

    Science.gov (United States)

    van den Donker, P.; Rosinga, G.; van Voorthuysen, E. du Marchie

    2016-05-01

    The first commercial CSP Central Receiver System has been in operation since 2007. The technology required for such a central receiver system is quite new. The determining factor of the price of electricity is the capital investment in the heliostat field. The cost level per square meter of the heliostat field is rather high. Sun2point is questioning the market development, which is trying to get the cost level down by aiming at large heliostats. Sun2Point aims at mass manufacturing small heliostats to achieve low prices. Mass manufacturing off-site and transport over long distances is possible for small heliostats only. Calibration on the spot is a labour-intensive activity. Autonomous, factory calibrated and wireless controlled heliostats are the solution to lower installation cost. A new measurement method that directly reports the orientation of the heliostat in relation to the earth and the sun can solve the calibration problem when the heliostats are installed. The application of small heliostats will be much cheaper as a result of this measurement method. In this paper several methods for such a measurement are described briefly. The new Sun2Point method has successfully been tested. In this paper Sun2Point challenges the CSP community to investigate this approach. A brief survey is presented of many aspects that lead to a low price.

  9. Manufacturing Cost/Design Guide (MC/DG) for Conceptual Design. Supplement

    Science.gov (United States)

    1989-08-01

    TOLERANCES 17-4PH Investment Cast 174PH Investment Cast 2 2 Zl 1au :0.01 ±0.02 ±0.03 0 -o.01 ±0.02 ±0.03 356/ A356 Aluminum 356/ A356 Aluminum Investment Cast...10% B +15% SAND CAST D OR C WITH 50% 8 +25% S+50% 356/ A356 DORC BASE ALUMINUM D OR C WITH 10% B +10% INVESTMENT D OR C WITH 50% B +20% CAST B +50...Increasing Supported support D-DI C E -C 7-V 2-51 EFFECT OF THROUGH & BUND HOLES ON THE COST OF CASTINGS 356/ A356 Aluminum Sand Castings 3 Blind Holes I

  10. Large-scale Manufacturing of Nanoparticulate-based Lubrication Additives for Improved Energy Efficiency and Reduced Emissions

    Energy Technology Data Exchange (ETDEWEB)

    Erdemir, Ali [Argonne National Laboratory

    2013-09-26

    This project was funded under the Department of Energy (DOE) Lab Call on Nanomanufacturing for Energy Efficiency and was directed toward the development of novel boron-based nanocolloidal lubrication additives for improving the friction and wear performance of machine components in a wide range of industrial and transportation applications. Argonne's research team concentrated on the scientific and technical aspects of the project, using a range of state-of-the art analytical and tribological test facilities. Argonne has extensive past experience and expertise in working with boron-based solid and liquid lubrication additives, and has intellectual property ownership of several. There were two industrial collaborators in this project: Ashland Oil (represented by its Valvoline subsidiary) and Primet Precision Materials, Inc. (a leading nanomaterials company). There was also a sub-contract with the University of Arkansas. The major objectives of the project were to develop novel boron-based nanocolloidal lubrication additives and to optimize and verify their performance under boundary-lubricated sliding conditions. The project also tackled problems related to colloidal dispersion, larger-scale manufacturing and blending of nano-additives with base carrier oils. Other important issues dealt with in the project were determination of the optimum size and concentration of the particles and compatibility with various base fluids and/or additives. Boron-based particulate additives considered in this project included boric acid (H{sub 3}BO{sub 3}), hexagonal boron nitride (h-BN), boron oxide, and borax. As part of this project, we also explored a hybrid MoS{sub 2} + boric acid formulation approach for more effective lubrication and reported the results. The major motivation behind this work was to reduce energy losses related to friction and wear in a wide spectrum of mechanical systems and thereby reduce our dependence on imported oil. Growing concern over greenhouse

  11. The Economics of Big Area Addtiive Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Post, Brian [Oak Ridge National Laboratory (ORNL); Lloyd, Peter D [ORNL; Lindahl, John [Oak Ridge National Laboratory (ORNL); Lind, Randall F [ORNL; Love, Lonnie J [ORNL; Kunc, Vlastimil [ORNL

    2016-01-01

    Case studies on the economics of Additive Manufacturing (AM) suggest that processing time is the dominant cost in manufacturing. Most additive processes have similar performance metrics: small part sizes, low production rates and expensive feedstocks. Big Area Additive Manufacturing is based on transitioning polymer extrusion technology from a wire to a pellet feedstock. Utilizing pellets significantly increases deposition speed and lowers material cost by utilizing low cost injection molding feedstock. The use of carbon fiber reinforced polymers eliminates the need for a heated chamber, significantly reducing machine power requirements and size constraints. We hypothesize that the increase in productivity coupled with decrease in feedstock and energy costs will enable AM to become more competitive with conventional manufacturing processes for many applications. As a test case, we compare the cost of using traditional fused deposition modeling (FDM) with BAAM for additively manufacturing composite tooling.

  12. Good ergonomics and team diversity reduce absenteeism and errors in car manufacturing.

    Science.gov (United States)

    Fritzsche, Lars; Wegge, Jürgen; Schmauder, Martin; Kliegel, Matthias; Schmidt, Klaus-Helmut

    2014-01-01

    Prior research suggests that ergonomics work design and mixed teams (in age and gender) may compensate declines in certain abilities of ageing employees. This study investigates simultaneous effects of both team level factors on absenteeism and performance (error rates) over one year in a sample of 56 car assembly teams (N = 623). Results show that age was related to prolonged absenteeism and more mistakes in work planning, but not to overall performance. In comparison, high-physical workload was strongly associated with longer absenteeism and increased error rates. Furthermore, controlling for physical workload, age diversity was related to shorter absenteeism, and the presence of females in the team was associated with shorter absenteeism and better performance. In summary, this study suggests that both ergonomics work design and mixed team composition may compensate age-related productivity risks in manufacturing by maintaining the work ability of older employees and improving job quality.

  13. Method of reducing multipole content in a conductor assembly during manufacture

    Energy Technology Data Exchange (ETDEWEB)

    Meinke, Rainer

    2016-05-24

    A method for manufacture of a conductor assembly. The assembly is of the type which, when conducting current, generates a magnetic field or in which, in the presence of a changing magnetic field, a voltage is induced. In an example embodiment one or more first coil rows are formed. The assembly has multiple coil rows about an axis with outer coil rows formed about inner coil rows. A determination is made of deviations from specifications associated with the formed one or more first coil rows. One or more deviations correspond to a magnitude of a multipole field component which departs from a field specification. Based on the deviations, one or more wiring patterns are generated for one or more second coil rows to be formed about the one or more first coil rows. The one or more second coil rows are formed in the assembly. The magnitude of each multipole field component that departs from the field specification is offset.

  14. Innovation in product design as a factor for reducing logistic and production costs

    Directory of Open Access Journals (Sweden)

    Luciana Fighera Marzall

    2016-03-01

    Full Text Available Innovation has been considered of fundamental importance for organizations competing in dynamic environments, which along with cost management has been shown as an organizational strategy that allows the company to measure its results and implement measures that impact on the organization's performance as a whole. This paper, carried out in a metal mechanical industry of a telecommunications engineering branch, aims to analyse cost reduction in logistics raw materials areas through innovation in the product design, which are antennas and towers for telephone networks. In terms of methodology, this study presents itself as a qualitative and quantitative research-action, which from the link between theory and practice allows for intervention in the middle of the researchers studied. As a result, an innovative project was developed, which allowed for the reduction costs of production by 68% and logistics by 32%. Despite the significant decrease in costs, the quality of manufactured products not declined and customer needs were met, thus making the company more competitive against competitors. Not widespread in the literature, this analysis of the impact on logistics and production costs due to improvements in the project is the main contribution theoretical of this paper.

  15. Optimizing power plant cycling operations while reducing generating plant damage and costs

    Energy Technology Data Exchange (ETDEWEB)

    Lefton, S.A.; Besuner, P.H.; Grimsrud, P. [Aptech Engineering Services, Inc., Sunnyvale, CA (United States); Bissel, A. [Electric Supply Board, Dublin (Ireland)

    1998-12-31

    This presentation describes a method for analyzing, quantifying, and minimizing the total cost of fossil, combined cycle, and pumped hydro power plant cycling operation. The method has been developed, refined, and applied during engineering studies at some 160 units in the United States and 8 units at the Irish Electric Supply Board (ESB) generating system. The basic premise of these studies was that utilities are underestimating the cost of cycling operation. The studies showed that the cost of cycling conventional boiler/turbine fossil power plants can range from between $2,500 and $500,000 per start-stop cycle. It was found that utilities typically estimate these costs by factors of 3 to 30 below actual costs and, thus, often significantly underestimate their true cycling costs. Knowledge of the actual, or total, cost of cycling will reduce power production costs by enabling utilities to more accurately dispatch their units to manage unit life expectancies, maintenance strategies and reliability. Utility management responses to these costs are presented and utility cost savings have been demonstrated. (orig.) 7 refs.

  16. System-Cost-Optimized Smart EVSE for Residential Application: Final Technical Report including Manufacturing Plan

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Charles [Delta Products, Triangle Park, NC (United States)

    2015-05-15

    In the 2nd quarter of 2012, a program was formally initiated at Delta Products to develop smart-grid-enabled Electric Vehicle Supply Equipment (EVSE) product for residential use. The project was funded in part by the U.S. Department of Energy (DOE), under award DE-OE0000590. Delta products was the prime contractor to DOE during the three year duration of the project. In addition to Delta Products, several additional supplier-partners were engaged in this research and development (R&D) program, including Detroit Edison DTE, Mercedes Benz Research and Development North America, and kVA. This report summarizes the program and describes the key research outcomes of the program. A technical history of the project activities is provided, which describes the key steps taken in the research and the findings made at successive stages in the multi-stage work. The evolution of an EVSE prototype system is described in detail, culminating in prototypes shipped to Department of Energy Laboratories for final qualification. After the program history is reviewed, the key attributes of the resulting EVSE are described in terms of functionality, performance, and cost. The results clearly demonstrate the ability of this EVSE to meet or exceed DOE's targets for this program, including: construction of a working product-intent prototype of a smart-grid-enabled EVSE, with suitable connectivity to grid management and home-energy management systems, revenue-grade metering, and related technical functions; and cost reduction of 50% or more compared to typical market priced EVSEs at the time of DOE's funding opportunity announcement (FOA), which was released in mid 2011. In addition to meeting all the program goals, the program was completed within the original budget and timeline established at the time of the award. The summary program budget and timeline, comparing plan versus actual values, is provided for reference, along with several supporting explanatory notes. Technical

  17. The costs and benefits of getting the ISO 9000 certification in the manufacturing sector in Saudi Arabia.

    Science.gov (United States)

    Mezher, T; Ramadan, H

    1998-01-01

    Many Saudi companies, in their journey to improve quality, efficiency and competitiveness, are pursuing and obtaining the ISO 9000 certificate. Many studies have evaluated how to implement ISO 9000 in different sectors, but none have analyzed the effectiveness of ISO 9000 certification (costs and benefits) on improving the overall quality and on meeting expectations. This study addressed these issues by investigating manufacturing organizations in Saudi Arabia that have the ISO 9000 certification. A survey questionnaire was distributed to firms throughout the kingdom. Thirty-two firms participated in the study. Results indicate that increased consistency of operations, improved service, and product quality are among the top motivators for pursuing the ISO certificate. The benefits most often experienced were improved awareness of procedural problems, better management control, keeping existing customers, increased customer satisfaction, and improved customer service. Difficulties experienced during the certification process involved time and cost, but these were not considered to be major problems. A high volume of paperwork was the main problem experienced following initial certification. Respondents in general said that the ISO 9000 certification met their expectations and that their level of satisfaction regarding the impact of ISO 9000 was high. Most recommended that other organizations pursue the certificate.

  18. Laser generated microstructures in tape cast electrodes for rapid electrolyte wetting: new technical approach for cost efficient battery manufacturing

    Science.gov (United States)

    Pfleging, W.; Kohler, R.; Pröll, J.

    2014-03-01

    Three-dimensional (3D) battery architectures are under current scientific investigation since they can achieve large areal energy capacities while maintaining high power densities. A main objective of surface patterning is the enhancement of lithium-ion diffusion which is often a limiting factor in lithium-ion cells. By using a rather new approach, laser material processing of thick-film electrodes has been investigated for the precise adjustment of 3D surface topography. Besides lithium-ion diffusion in electrode materials as an electrochemically limited process, a critical step in lithium-ion pouch cell manufacturing is the homogeneous electrolyte wetting of stacked electrodes and separators. This process requires cost expensive and time-consuming vacuum and storage processes at elevated temperatures. A new and cost efficient laser process has been successfully applied in order to significantly improve the electrode wetting and the battery operation. Preliminary investigations for testing the process on pouch cell geometry revealed higher capacities and increased cell life-time compared to standard cells without storage processes at elevated temperatures. The laser structuring process can be applied to commercial electrode materials and integrated into existing production lines.

  19. Photovoltaic manufacturing cost and throughput improvements for thin-film CIGS-based modules: Phase 1 technical report, July 1998--July 1999

    Energy Technology Data Exchange (ETDEWEB)

    Wiedeman, S.; Wendt, R.G.

    2000-03-01

    The primary objectives of the Global Solar Energy (GSE) Photovoltaic Manufacturing Technology (PVMaT) subcontract are directed toward reducing cost and expanding the production rate of thin-film CuInGaSe{sub 2} (CIGS)-based PV modules on flexible substrates. Improvements will be implemented in monolithic integration, CIGS deposition, contact deposition, and in-situ CIGS control and monitoring. In Phase 1, GSE has successfully attacked many of the highest risk aspects of each task. All-laser, selective scribing processes for CIGS have been developed, and many end-of-contract goals for scribing speed have been exceeded in the first year. High-speed ink-jet deposition of insulating material in the scribes now appears to be a viable technique, again exceeding some end-of-contract goals in the first year. Absorber deposition of CIGS was reduced corresponding to throughput speeds of up to 24-in/min, also exceeding an end-of-contract goal. Alternate back-contact materials have been identified that show potential as candidates for replacement of higher-cost molybdenum, and a novel, real-time monitoring technique (parallel-detector spectroscopic ellipsometry) has shown remarkable sensitivity to relevant properties of the CIGS absorber layer for use as a diagnostic tool. Currently, one of the bilayers has been baselined by GSE for flexible CIGS on polymeric substrates. Resultant back-contacts meet sheet-resistance goals and exhibit much less intrinsic stress than Mo. CIGS has been deposited, and resultant devices are comparable in performance to pure Mo back-contacts. Debris in the chamber has been substantially reduced, allowing longer roll-length between system cleaning.

  20. Manufacturing cost analysis of a parabolic dish concentrator (General Electric design) for solar thermal electric power systems in selected production volumes

    Science.gov (United States)

    1981-01-01

    The manufacturing cost of a General Electric 12 meter diameter concentrator was estimated. This parabolic dish concentrator for solar thermal system was costed in annual production volumes of 100 - 1,000 - 5,000 - 10,000 - 50,000 100,000 - 400,000 and 1,000,000 units. Presented for each volume are the costs of direct labor, material, burden, tooling, capital equipment and buildings. Also presented is the direct labor personnel and factory space requirements. All costs are based on early 1981 economics.

  1. Spatial analyses of cost efficient measures to reduce N-leaching

    DEFF Research Database (Denmark)

    Jacobsen, Brian H.; Abildtrup, Jens; Ørum, Jens Erik

    (WFD). The analysis shows that the geographical position of the measures are very important in order to achieve the expected nutrient reduction. The current income varies a lot in the River basin and this might influence the choice of cost effective measures to reduce nutrient load. Furthermore a close......The Nitrate Directive has only been implemented satisfactorily in a few EU countries. The Commission have accepted the Danish implementation of the directive based on the Plan for the Aquatic Environment II. The costs of this plan has been calculated to 70 million € or 2,0 € per kg N in reduced...... leaching. The farmers have paid 60% of the costs. The paper then describes an example of a regional analysis covering the River Basin of Ringkøbing Fjord in Denmark, which indicates the type of calculations needed to find the measures and costs in order to comply with parts of the Water Framework Directive...

  2. Surgeon ownership in medical device distribution: does it actually reduce healthcare costs?

    Science.gov (United States)

    Steinmann, John C; Edwards, Charles; Eickmann, Thomas; Carlson, Angela; Blight, Alexis

    2015-01-01

    Surgeon ownership in medical device distribution is a new model that proposes to reduce the costs associated with surgical implants. In surgeon-owned distributorships (SDs), the surgeon becomes the purchaser through ownership and management of a distributorship. The purpose of this study is to determine whether significant cost savings can result from SDs. Five existing SDs were retrospectively reviewed, and their implant pricing was compared with non-SDs. The hospital pricing for implants supplied by the SDs was compared with 2010 pricing from the best contract/capitated rate for like implants from non-SDs. The average first-year cost savings for the SDs was 36%, with US$2,456,521 total savings in 2010. For distributorships in business for over 2 years, the average annual price from the SDs actually decreased by 1.41%. This study demonstrates that SDs are capable of providing substantial healthcare savings through lower implant costs and reduced annual price escalations.

  3. A New Method for Low Cost Production of Titanium Alloys for Reducing Energy Consumption of Mechanical Systems

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Z. Zak [Univ. of Utah, Salt Lake City, UT (United States); Chandran, Ravi [Univ. of Utah, Salt Lake City, UT (United States); Koopman, Mark [Univ. of Utah, Salt Lake City, UT (United States)

    2016-02-29

    This project investigated an innovative manufacturing process intended to minimize the cost of production of titanium materials and components, and increase the adoption of Ti components for energy consuming applications, such as automobiles. A key innovation of the proposed manufacturing approach is a novel Ti powder sintering technology for making titanium materials with ultrafine grain microstructure in the as-sintered state with minimum, or an absence, of post-sintering processes. The new sintering technology is termed Hydrogen Sintering and Phase Transformations (HSPT), and constitutes a promising manufacturing technology that can be used to produce titanium (Ti) materials and components in a near-net-shape form, thus also minimizing machining costs. Our objective was to meet, or possibly surpass, the mechanical property levels for ASTM B348 Grade 5 for wrought Ti-6Al-4V. Although specific applications call for varying mechanical property requirements, ASTM B348 was created for the demanding applications of the aerospace industry, and is the established standard for Ti-6Al-4V. While the primary goal was to meet, or exceed this standard, the team also had the goal of demonstrating this could be done at a significantly lower cost of production. Interim goals of the project were to fully develop this novel sintering process, and provide sufficient baseline testing to make the method practical and attractive to industry. By optimizing the process parameters for the sintering of titanium hydride (TiH2) powders in a hydrogen atmosphere and controlling the phase transformations during and after sintering, the HSPT process was expected to reduce the energy consumption, and thus cost, of making Ti alloys and fabricating Ti components. The process was designed such that no high temperature melting is required for producing Ti alloys; little or no post-sintering processing is needed for producing desired microstructures (and therefore enhanced mechanical

  4. The cost of reducing CO2 emissions - methodological approach, illustrated by the Danish energy plan

    DEFF Research Database (Denmark)

    Morthorst, P.E.

    1998-01-01

    available. One of the tools available for this purpose is the construction of cost-reduction curves, relating the marginal cost of CO2 reduction and the quantity of the reduced emission to specific technology options. This paper outlines different approaches for establishing cost-reduction curves for CO2...... those technological options that have the highest reduction potential and the lowest marginal costs, and vice versa. Based on the case of the Danish energy plan, the results of the analyses show that a number of reduction options with significant reduction potentials are available at relatively low...... marginal costs. Among others can be mentioned increased use of combined heat and power (CHP), substituting conventional coal-fired CHP plants with biomass ones and the development of offshore wind turbines: (C) 1998 Elsevier Science Ltd. All rights reserved....

  5. Using adhesives as a means to reduce costs and increase performance in the production of photovoltaic electricity.

    Science.gov (United States)

    Thorey, Claire

    2013-01-01

    Although adhesives have been used for many years to manufacture cars in more efficient ways, their potential has not yet been fully exploited by the renewable energy industry. We argue in this article that photovoltaic module manufacturers can save costs and differentiate from competition by careful selection and use of their bonding systems. Clever adhesives can enable new, more effective product designs and can play a major role in the longevity of the complete product.

  6. Costs of Reducing Greenhouse Gas Emissions: A Case Study of India’s Power Generation Sector

    OpenAIRE

    Gupta, Manish

    2006-01-01

    If India were to participate in any international effort towards mitigating CO2 emissions, the power sector which is one of the largest emitters of CO2 in the country would be required to play a major role. In this context the study estimates the marginal abatement costs, which correspond to the costs incurred by the power plants to reduce one unit of CO2 from the current level. The study uses an output distance function approach and its duality with the revenue function to derive these costs...

  7. A Simple Exoskeleton That Assists Plantarflexion Can Reduce the Metabolic Cost of Human Walking

    Science.gov (United States)

    Malcolm, Philippe; Derave, Wim; Galle, Samuel; De Clercq, Dirk

    2013-01-01

    Background Even though walking can be sustained for great distances, considerable energy is required for plantarflexion around the instant of opposite leg heel contact. Different groups attempted to reduce metabolic cost with exoskeletons but none could achieve a reduction beyond the level of walking without exoskeleton, possibly because there is no consensus on the optimal actuation timing. The main research question of our study was whether it is possible to obtain a higher reduction in metabolic cost by tuning the actuation timing. Methodology/Principal Findings We measured metabolic cost by means of respiratory gas analysis. Test subjects walked with a simple pneumatic exoskeleton that assists plantarflexion with different actuation timings. We found that the exoskeleton can reduce metabolic cost by 0.18±0.06 W kg−1 or 6±2% (standard error of the mean) (p = 0.019) below the cost of walking without exoskeleton if actuation starts just before opposite leg heel contact. Conclusions/Significance The optimum timing that we found concurs with the prediction from a mathematical model of walking. While the present exoskeleton was not ambulant, measurements of joint kinetics reveal that the required power could be recycled from knee extension deceleration work that occurs naturally during walking. This demonstrates that it is theoretically possible to build future ambulant exoskeletons that reduce metabolic cost, without power supply restrictions. PMID:23418524

  8. The Dynamics of Bertrand Price Competition with Cost-Reducing Investments

    DEFF Research Database (Denmark)

    Iskhakov, Fedor; Rust, John; Schjerning, Bertel

    We present a dynamic extension of the classic static model of Bertrand price competition that allows competing duopolists to undertake cost-reducing investments in an attempt to “leapfrog” their rival to attain low-cost leadership – at least temporarily. We show that leapfrogging occurs in equili......We present a dynamic extension of the classic static model of Bertrand price competition that allows competing duopolists to undertake cost-reducing investments in an attempt to “leapfrog” their rival to attain low-cost leadership – at least temporarily. We show that leapfrogging occurs...... in equilibrium, resolving the Bertrand investment paradox., i.e. leapfrogging explains why firms have an ex ante incentive to undertake cost-reducing investments even though they realize that simultaneous investments to acquire the state of the art production technology would result in Bertrand price competition...... in the product market that drives their ex post profits to zero. Our analysis provides a new interpretation of “price wars”. Instead of constituting a punishment for a breakdown of tacit collusion, price wars are fully competitive outcomes that occur when one firm leapfrogs its rival to become the new low cost...

  9. A simple exoskeleton that assists plantarflexion can reduce the metabolic cost of human walking.

    Directory of Open Access Journals (Sweden)

    Philippe Malcolm

    Full Text Available BACKGROUND: Even though walking can be sustained for great distances, considerable energy is required for plantarflexion around the instant of opposite leg heel contact. Different groups attempted to reduce metabolic cost with exoskeletons but none could achieve a reduction beyond the level of walking without exoskeleton, possibly because there is no consensus on the optimal actuation timing. The main research question of our study was whether it is possible to obtain a higher reduction in metabolic cost by tuning the actuation timing. METHODOLOGY/PRINCIPAL FINDINGS: We measured metabolic cost by means of respiratory gas analysis. Test subjects walked with a simple pneumatic exoskeleton that assists plantarflexion with different actuation timings. We found that the exoskeleton can reduce metabolic cost by 0.18±0.06 W kg(-1 or 6±2% (standard error of the mean (p = 0.019 below the cost of walking without exoskeleton if actuation starts just before opposite leg heel contact. CONCLUSIONS/SIGNIFICANCE: The optimum timing that we found concurs with the prediction from a mathematical model of walking. While the present exoskeleton was not ambulant, measurements of joint kinetics reveal that the required power could be recycled from knee extension deceleration work that occurs naturally during walking. This demonstrates that it is theoretically possible to build future ambulant exoskeletons that reduce metabolic cost, without power supply restrictions.

  10. Reducing Emissions from Deforestation and Forest Degradation (REDD+: Transaction Costs of Six Peruvian Projects

    Directory of Open Access Journals (Sweden)

    Olivia R. Rendón Thompson

    2013-03-01

    Full Text Available Reduced Emissions from Deforestation and Forest Degradation (REDD+ has received strong support as a major component of future global climate change policy. The financial mechanism of REDD+ is payment for the ecosystem service of carbon sequestration in tropical forests that is expected to create incentives for conservation of forest cover and condition. However, the costs of achieving emissions reduction by these means remain largely unknown. We assess the set-up, implementation, and monitoring costs, i.e., collectively the transaction costs, of six of the first seven REDD+ project designs from the Peruvian Amazon and compare them with established projects in Brazil and Bolivia. The estimated costs vary greatly among the assessed projects from US$0.16 to 1.44 ha-1 yr-1, with an average of US$0.73 ha-1 yr-1, though they are comparable to earlier published estimates. The results indicate that the costs of implementing REDD+ are highly uncertain for participating developing countries because of issues such as inadequate project design and how additionality is determined. Furthermore, some insight is obtained into how different activities to reduce deforestation and forest degradation, the type of implementer, and project location affect implementation costs of REDD+ projects. Even with these first estimates, the cost of preserving existing intact forests in the Peruvian Amazon may have been underestimated.

  11. Context-aware computing-based reducing cost of service method in resource discovery and interaction

    Institute of Scientific and Technical Information of China (English)

    TANG Shan-cheng; HOU Yi-bin

    2004-01-01

    Reducing cost of service is an important goal for resource discovery and interaction technologies. The shortcomings of transhipment-method and hibernation-method are to increase holistic cost of service and to slower resource discovery respectively. To overcome these shortcomings, a context-aware computing-based method is developed. This method, firstly,analyzes the courses of devices using resource discovery and interaction technologies to identify some types of context related to reducing cost of service, then, chooses effective methods such as stopping broadcast and hibernation to reduce cost of service according to information supplied by the context but not the transhipment-method's simple hibernations. The results of experiments indicate that under the worst condition this method overcomes the shortcomings of transhipment-method, makes the "poor" devices hibernate longer than hibernation-method to reduce cost of service more effectively, and discovers resources faster than hibernation-method; under the best condition it is far better than hibernation-method in all aspects.

  12. A method for manufacturing superior set yogurt under reduced oxygen conditions.

    Science.gov (United States)

    Horiuchi, H; Inoue, N; Liu, E; Fukui, M; Sasaki, Y; Sasaki, T

    2009-09-01

    The yogurt starters Lactobacillus delbrueckii ssp. bulgaricus and Streptococcus thermophilus are well-known facultatively anaerobic bacteria that can grow in oxygenated environments. We found that they removed dissolved oxygen (DO) in a yogurt mix as the fermentation progressed and that they began to produce acid actively after the DO concentration in the yogurt mix was reduced to 0 mg/kg, suggesting that the DO retarded the production of acid. Yogurt fermentation was carried out at 43 or 37 degrees C both after the DO reduction treatment and without prior treatment. Nitrogen gas was mixed and dispersed into the yogurt mix after inoculation with yogurt starter culture to reduce the DO concentration in the yogurt mix. The treatment that reduced DO concentration in the yogurt mix to approximately 0 mg/kg beforehand caused the starter culture LB81 used in this study to enter into the exponential growth phase earlier. Furthermore, the combination of reduced DO concentration in the yogurt mix beforehand and incubation at a lower temperature (37 degrees C) resulted in a superior set yogurt with a smooth texture and strong curd structure.

  13. 27 CFR 479.32a - Reduced rate of tax for small importers and manufacturers.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Reduced rate of tax for... BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES, AND CERTAIN OTHER FIREARMS Special (Occupational) Taxes §...

  14. Does recyclable separation reduce the cost of municipal waste management in Japan?

    Science.gov (United States)

    Chifari, Rosaria; Lo Piano, Samuele; Matsumoto, Shigeru; Tasaki, Tomohiro

    2017-02-01

    Municipal solid waste (MSW) management is a system involving multiple sub-systems that typically require demanding inputs, materials and resources to properly process generated waste throughput. For this reason, MSW management is generally one of the most expensive services provided by municipalities. In this paper, we analyze the Japanese MSW management system and estimate the cost elasticity with respect to the waste volumes at three treatment stages: collection, processing, and disposal. Although we observe economies of scale at all three stages, the collection cost is less elastic than the disposal cost. We also examine whether source separation at home affects the cost of MSW management. The empirical results show that the separate collection of the recyclable fraction leads to reduced processing costs at intermediate treatment facilities, but does not change the overall waste management cost. Our analysis also reveals that the cost of waste management systems decreases when the service is provided by private companies through a public tender. The cost decreases even more when the service is performed under the coordination of adjacent municipalities. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. 基于SD的制造企业物流运作成本仿真与优化%Manufacturing enterprise's logistics operational cost simulation and optimization based on system dynamics

    Institute of Scientific and Technical Information of China (English)

    王超; 穆东

    2012-01-01

    Logistics cost control is always an academic and business circles' hot topic and the enterprise can effectively reduces business costs by controlling this "black continent". This paper built the structure model of manufacturing enterprise's logistics operational cost, and simulated the model: a case study of Tianjin handicraft firm, finally proposed some optimizational tactics. The research results indicated that the complex relation among factors of manufacturing enterprise's logistics operational cost system could be better revealed with the use of system dynamics methodology and the method proposed can provide guides and references for logistics cost control.%本文使用系统动力学方法构建制造企业物流运作成本的结构模型,并以天津手工艺品制造企业——THF为例,进行模拟仿真并提出优化方案.结果表明:将系统动力学应用于制造企业物流运作成本控制可以较好地反映所研究系统内因素间的复杂关系,该方法可为物流成本控制提供指导与借鉴.

  16. Cost analysis of roll-to-roll fabricated ITO free single and tandem organic solar modules based on data from manufacture

    DEFF Research Database (Denmark)

    Machui, Florian; Hösel, Markus; Li, Ning

    2014-01-01

    We present a cost analysis based on state of the art printing and coating processes to fully encapsulated, flexible ITO- and vacuum-free polymer solar cell modules. Manufacturing data for both single junctions and tandem junctions are presented and analyzed. Within this calculation the most expen...

  17. Subthalamic Nucleus Deep Brain Stimulation May Reduce Medication Costs in Early Stage Parkinson's Disease.

    Science.gov (United States)

    Hacker, Mallory L; Currie, Amanda D; Molinari, Anna L; Turchan, Maxim; Millan, Sarah M; Heusinkveld, Lauren E; Roach, Jonathon; Konrad, Peter E; Davis, Thomas L; Neimat, Joseph S; Phibbs, Fenna T; Hedera, Peter; Byrne, Daniel W; Charles, David

    2016-01-01

    Subthalamic nucleus deep brain stimulation (STN-DBS) is well-known to reduce medication burden in advanced stage Parkinson's disease (PD). Preliminary data from a prospective, single blind, controlled pilot trial demonstrated that early stage PD subjects treated with STN-DBS also required less medication than those treated with optimal drug therapy (ODT). The purpose of this study was to analyze medication cost and utilization from the pilot trial of DBS in early stage PD and to project 10 year medication costs. Medication data collected at each visit were used to calculate medication costs. Medications were converted to levodopa equivalent daily dose, categorized by medication class, and compared. Medication costs were projected to advanced stage PD, the time when a typical patient may be offered DBS. Medication costs increased 72% in the ODT group and decreased 16% in the DBS+ODT group from baseline to 24 months. This cost difference translates into a cumulative savings for the DBS+ODT group of $7,150 over the study period. Projected medication cost savings over 10 years reach $64,590. Additionally, DBS+ODT subjects were 80% less likely to require polypharmacy compared with ODT subjects at 24 months (p early PD reduced medication cost over the two-year study period. DBS may offer substantial long-term reduction in medication cost by maintaining a simplified, low dose medication regimen. Further study is needed to confirm these findings, and the FDA has approved a pivotal, multicenter clinical trial evaluating STN-DBS in early PD.

  18. Subthalamic Nucleus Deep Brain Stimulation May Reduce Medication Costs in Early Stage Parkinson’s Disease

    Science.gov (United States)

    Hacker, Mallory L.; Currie, Amanda D.; Molinari, Anna L.; Turchan, Maxim; Millan, Sarah M.; Heusinkveld, Lauren E.; Roach, Jonathon; Konrad, Peter E.; Davis, Thomas L.; Neimat, Joseph S.; Phibbs, Fenna T.; Hedera, Peter; Byrne, Daniel W.; Charles, David

    2016-01-01

    Background: Subthalamic nucleus deep brain stimulation (STN-DBS) is well-known to reduce medication burden in advanced stage Parkinson’s disease (PD). Preliminary data from a prospective, single blind, controlled pilot trial demonstrated that early stage PD subjects treated with STN-DBS also required less medication than those treated with optimal drug therapy (ODT). Objective: The purpose of this study was to analyze medication cost and utilization from the pilot trial of DBS in early stage PD and to project 10 year medication costs. Methods: Medication data collected at each visit were used to calculate medication costs. Medications were converted to levodopa equivalent daily dose, categorized by medication class, and compared. Medication costs were projected to advanced stage PD, the time when a typical patient may be offered DBS. Results: Medication costs increased 72% in the ODT group and decreased 16% in the DBS+ODT group from baseline to 24 months. This cost difference translates into a cumulative savings for the DBS+ODT group of $7,150 over the study period. Projected medication cost savings over 10 years reach $64,590. Additionally, DBS+ODT subjects were 80% less likely to require polypharmacy compared with ODT subjects at 24 months (p <  0.05; OR = 0.2; 95% CI: 0.04–0.97). Conclusions: STN-DBS in early PD reduced medication cost over the two-year study period. DBS may offer substantial long-term reduction in medication cost by maintaining a simplified, low dose medication regimen. Further study is needed to confirm these findings, and the FDA has approved a pivotal, multicenter clinical trial evaluating STN-DBS in early PD. PMID:26967937

  19. Reduced fecundity is the cost of cheating in RNA virus phi6.

    Science.gov (United States)

    Dennehy, John J.; Turner, Paul E.

    2004-01-01

    Co-infection by multiple viruses affords opportunities for the evolution of cheating strategies to use intracellular resources. Cheating may be costly, however, when viruses infect cells alone. We previously allowed the RNA bacteriophage phi6 to evolve for 250 generations in replicated environments allowing co-infection of Pseudomonas phaseolicola bacteria. Derived genotypes showed great capacity to compete during co-infection, but suffered reduced performance in solo infections. Thus, the evolved viruses appear to be cheaters that sacrifice between-host fitness for within-host fitness. It is unknown, however, which stage of the lytic growth cycle is linked to the cost of cheating. Here, we examine the cost through burst assays, where lytic infection can be separated into three discrete phases (analogous to phage life history): dispersal stage, latent period (juvenile stage), and burst (adult stage). We compared growth of a representative cheater and its ancestor in environments where the cost occurs. The cost of cheating was shown to be reduced fecundity, because cheaters feature a significantly smaller burst size (progeny produced per infected cell) when infecting on their own. Interestingly, latent period (average burst time) of the evolved virus was much longer than that of the ancestor, indicating the cost does not follow a life history trade-off between timing of reproduction and lifetime fecundity. Our data suggest that interference competition allows high fitness of derived cheaters in mixed infections, and we discuss preferential encapsidation as one possible mechanism. PMID:15539353

  20. Costs and efficacy of public health interventions to reduce aflatoxin–induced human disease

    Science.gov (United States)

    Khlangwiset, Pornsri; Wu, Felicia

    2010-01-01

    This study reviews available information on the economics and efficacy of aflatoxin risk-reduction interventions, and provides an approach for analysis of the cost-effectiveness of public health interventions to reduce aflatoxin-induced human disease. Many strategies have been developed to reduce aflatoxin or its adverse effects in the body. However, a question that has been under-addressed is how likely these strategies will be adopted in the countries that need them most to improve public health. This study evaluates two aspects crucial to adoption of new technologies and methods: the costs and the efficacy of different strategies. First, we describe and categorize different aflatoxin risk-reduction strategies into preharvest, postharvest, dietary, and clinical settings. Then we compile and discuss relevant data on the costs and efficacy of each strategy, in reducing either aflatoxin in food or its metabolites in the body. In addition, we describe which crops are affected by each intervention, who is likely to pay for the control strategy, and who is likely to benefit. A framework is described for how to evaluate cost-effectiveness of strategies according to World Health Organization standards. Finally, we discuss which strategies are likely to be cost-effective and helpful under different conditions worldwide of regulations, local produce and soil ecology, and potential health emergencies. PMID:20419532

  1. Cost-effectiveness of universal rotavirus vaccination in reducing rotavirus gastroenteritis in Ireland.

    LENUS (Irish Health Repository)

    Tilson, L

    2011-10-06

    We evaluated the cost-effectiveness of universal infant rotavirus (RV) vaccination compared to current standard of care of "no vaccination". Two RV vaccines are currently licensed in Ireland: Rotarix and RotaTeq. A cohort model used in several European countries was adapted using Irish epidemiological, resource utilisation and cost data. The base case model considers the impact of Rotarix vaccination on health-related quality of life of children under five years old from a healthcare payer perspective. Other scenarios explored the use of RotaTeq, impact on one caregiver, on societal costs and on cases that do not seek medical attention. Cost was varied between the vaccine list price (€100\\/course) in the base case and an assumed tender price (€70\\/course). One-way and probabilistic sensitivity analyses were conducted. Implementing universal RV vaccination may prevent around 1970 GP visits, 3280 A&E attendances and 2490 hospitalisations. A vaccination programme was estimated to cost approximately €6.54 million per year but €4.65 million of this would be offset by reducing healthcare resource use. The baseline ICER was €112,048\\/QALY and €72,736\\/QALY from the healthcare payer and societal perspective, respectively, falling to €68,896 and €43,916\\/QALY, respectively, if the impact on one caregiver was considered. If the price fell to €70 per course, universal RV vaccination would be cost saving under all scenarios. Results were sensitive to vaccination costs, incidence of RV infection and direct medical costs. Universal RV vaccination would not be cost-effective under base case assumptions. However, it could be cost-effective at a lower vaccine price or from a wider societal perspective.

  2. Linking Reduced Deforestation and a Global Carbon Market: Impacts on Costs, Financial Flows, and Technological Innovation

    OpenAIRE

    Bosetti, Valentina; Lubowski, Ruben; Golub, Alexander; Markandya, Anil

    2010-01-01

    Discussions of tropical deforestation are currently at the forefront of climate change policy negotiations at national, regional, and international levels. This paper analyzes the effects of linking Reduced Emissions from Deforestation and Forest Degradation (REDD) to a global market for greenhouse gas emission reductions. We supplement a global climate-energy-economy model with alternative cost estimates for reducing deforestation emissions in order to examine a global program for stabilizin...

  3. The role of technology in reducing health care costs. Phase II and phase III.

    Energy Technology Data Exchange (ETDEWEB)

    Cilke, John F.; Parks, Raymond C.; Funkhouser, Donald Ray; Tebo, Michael A.; Murphy, Martin D.; Hightower, Marion Michael; Gallagher, Linda K.; Craft, Richard Layne, II; Garcia, Rudy John

    2004-04-01

    In Phase I of this project, reported in SAND97-1922, Sandia National Laboratories applied a systems approach to identifying innovative biomedical technologies with the potential to reduce U.S. health care delivery costs while maintaining care quality. The effort provided roadmaps for the development and integration of technology to meet perceived care delivery requirements and an economic analysis model for development of care pathway costs for two conditions: coronary artery disease (CAD) and benign prostatic hypertrophy (BPH). Phases II and III of this project, which are presented in this report, were directed at detailing the parameters of telemedicine that influence care delivery costs and quality. These results were used to identify and field test the communication, interoperability, and security capabilities needed for cost-effective, secure, and reliable health care via telemedicine.

  4. Reduce operational cost and extend the life of pipeline infrastructure by automating remote cathodic protection systems

    Energy Technology Data Exchange (ETDEWEB)

    Rosado, Elroy [Freewave Technologies, Inc., Boulder, CO (United States). Latin America

    2009-07-01

    Energy and Pipeline Companies wrestle to control operating costs largely affected by new government regulations, ageing buried metal assets, rising steel prices, expanding pipeline operations, new interference points, HCA encroachment, restrictive land use policies, heightened network security, and an ageing soon-to-retire work force. With operating costs on the rise, seemingly out of control, many CP and Operations Professionals look to past best practices in cost containment through automation. Many companies achieve solid business results through deployment of telemetry and SCADA automation of remote assets and now hope to expand this success to further optimize operations by automating remote cathodic protection systems. This presentation will provide examples of how new remote cathodic protection systems are helping energy and pipeline companies address the growing issue of the aging pipeline infrastructure and reduce their costs while optimizing their operations. (author)

  5. Reducing operating costs for struvite formation with a carbon dioxide stripper.

    Science.gov (United States)

    Fattah, K P; Sabrina, N; Mavinic, D S; Koch, F A

    2008-01-01

    One of the major operational costs of phosphorus recovery as struvite is the cost of caustic chemical that is added to maintain a desired level of operative pH. A study was conducted at the Lulu Island Wastewater Treatment Plant (LIWWTP), Richmond, BC, using a struvite crystallizer and a cascade stripper designed at the University of British Columbia (UBC). The stripper was tested under different operating conditions to determine the effectiveness of CO(2) stripping in increasing the pH of the water matrix and thereby reducing caustic chemical use. This reduction is expected to reduce the operational costs of struvite production. Throughout the project, a high percentage (90%) of phosphorus removal was achieved under each condition. The cascade stripper was very effective in saving caustic usage, ranging from 35% to 86%, depending on the operating conditions. However, the stripper showed relatively poor performance regarding ammonia stripping.

  6. An Active Learning Classifier for Further Reducing Diabetic Retinopathy Screening System Cost

    Directory of Open Access Journals (Sweden)

    Yinan Zhang

    2016-01-01

    Full Text Available Diabetic retinopathy (DR screening system raises a financial problem. For further reducing DR screening cost, an active learning classifier is proposed in this paper. Our approach identifies retinal images based on features extracted by anatomical part recognition and lesion detection algorithms. Kernel extreme learning machine (KELM is a rapid classifier for solving classification problems in high dimensional space. Both active learning and ensemble technique elevate performance of KELM when using small training dataset. The committee only proposes necessary manual work to doctor for saving cost. On the publicly available Messidor database, our classifier is trained with 20%–35% of labeled retinal images and comparative classifiers are trained with 80% of labeled retinal images. Results show that our classifier can achieve better classification accuracy than Classification and Regression Tree, radial basis function SVM, Multilayer Perceptron SVM, Linear SVM, and K Nearest Neighbor. Empirical experiments suggest that our active learning classifier is efficient for further reducing DR screening cost.

  7. An assessment of monitoring requirements and costs of 'Reduced Emissions from Deforestation and Degradation'

    Directory of Open Access Journals (Sweden)

    McCallum Ian

    2009-08-01

    Full Text Available Abstract Background Negotiations on a future climate policy framework addressing Reduced Emissions from Deforestation and Degradation (REDD are ongoing. Regardless of how such a framework will be designed, many technical solutions of estimating forest cover and forest carbon stock change exist to support policy in monitoring and accounting. These technologies typically combine remotely sensed data with ground-based inventories. In this article we assess the costs of monitoring REDD based on available technologies and requirements associated with key elements of REDD policy. Results We find that the design of a REDD policy framework (and specifically its rules can have a significant impact on monitoring costs. Costs may vary from 0.5 to 550 US$ per square kilometre depending on the required precision of carbon stock and area change detection. Moreover, they follow economies of scale, i.e. single country or project solutions will face relatively higher monitoring costs. Conclusion Although monitoring costs are relatively small compared to other cost items within a REDD system, they should be shared not only among countries but also among sectors, because an integrated monitoring system would have multiple benefits for non-REDD management. Overcoming initialization costs and unequal access to monitoring technologies is crucial for implementation of an integrated monitoring system, and demands for international cooperation.

  8. SunShot solar power reduces costs and uncertainty in future low-carbon electricity systems.

    Science.gov (United States)

    Mileva, Ana; Nelson, James H; Johnston, Josiah; Kammen, Daniel M

    2013-08-20

    The United States Department of Energy's SunShot Initiative has set cost-reduction targets of $1/watt for central-station solar technologies. We use SWITCH, a high-resolution electricity system planning model, to study the implications of achieving these targets for technology deployment and electricity costs in western North America, focusing on scenarios limiting carbon emissions to 80% below 1990 levels by 2050. We find that achieving the SunShot target for solar photovoltaics would allow this technology to provide more than a third of electric power in the region, displacing natural gas in the medium term and reducing the need for nuclear and carbon capture and sequestration (CCS) technologies, which face technological and cost uncertainties, by 2050. We demonstrate that a diverse portfolio of technological options can help integrate high levels of solar generation successfully and cost-effectively. The deployment of GW-scale storage plays a central role in facilitating solar deployment and the availability of flexible loads could increase the solar penetration level further. In the scenarios investigated, achieving the SunShot target can substantially mitigate the cost of implementing a carbon cap, decreasing power costs by up to 14% and saving up to $20 billion ($2010) annually by 2050 relative to scenarios with Reference solar costs.

  9. Cost-effectiveness of newborn circumcision in reducing lifetime HIV risk among U.S. males.

    Directory of Open Access Journals (Sweden)

    Stephanie L Sansom

    Full Text Available BACKGROUND: HIV incidence was substantially lower among circumcised versus uncircumcised heterosexual African men in three clinical trials. Based on those findings, we modeled the potential effect of newborn male circumcision on a U.S. male's lifetime risk of HIV, including associated costs and quality-adjusted life-years saved. METHODOLOGY/PRINCIPAL FINDINGS: Given published estimates of U.S. males' lifetime HIV risk, we calculated the fraction of lifetime risk attributable to heterosexual behavior from 2005-2006 HIV surveillance data. We assumed 60% efficacy of circumcision in reducing heterosexually-acquired HIV over a lifetime, and varied efficacy in sensitivity analyses. We calculated differences in lifetime HIV risk, expected HIV treatment costs and quality-adjusted life years (QALYs among circumcised versus uncircumcised males. The main outcome measure was cost per HIV-related QALY saved. Circumcision reduced the lifetime HIV risk among all males by 15.7% in the base case analysis, ranging from 7.9% for white males to 20.9% for black males. Newborn circumcision was a cost-saving HIV prevention intervention for all, black and Hispanic males. The net cost of newborn circumcision per QALY saved was $87,792 for white males. Results were most sensitive to the discount rate, and circumcision efficacy and cost. CONCLUSIONS/SIGNIFICANCE: Newborn circumcision resulted in lower expected HIV-related treatment costs and a slight increase in QALYs. It reduced the 1.87% lifetime risk of HIV among all males by about 16%. The effect varied substantially by race and ethnicity. Racial and ethnic groups who could benefit the most from circumcision may have least access to it due to insurance coverage and state Medicaid policies, and these financial barriers should be addressed. More data on the long-term protective effect of circumcision on heterosexual males as well as on its efficacy in preventing HIV among MSM would be useful.

  10. Fitness costs of animal medication: antiparasitic plant chemicals reduce fitness of monarch butterfly hosts.

    Science.gov (United States)

    Tao, Leiling; Hoang, Kevin M; Hunter, Mark D; de Roode, Jacobus C

    2016-09-01

    The emerging field of ecological immunology demonstrates that allocation by hosts to immune defence against parasites is constrained by the costs of those defences. However, the costs of non-immunological defences, which are important alternatives to canonical immune systems, are less well characterized. Estimating such costs is essential for our understanding of the ecology and evolution of alternative host defence strategies. Many animals have evolved medication behaviours, whereby they use antiparasitic compounds from their environment to protect themselves or their kin from parasitism. Documenting the costs of medication behaviours is complicated by natural variation in the medicinal components of diets and their covariance with other dietary components, such as macronutrients. In the current study, we explore the costs of the usage of antiparasitic compounds in monarch butterflies (Danaus plexippus), using natural variation in concentrations of antiparasitic compounds among plants. Upon infection by their specialist protozoan parasite Ophryocystis elektroscirrha, monarch butterflies can selectively oviposit on milkweed with high foliar concentrations of cardenolides, secondary chemicals that reduce parasite growth. Here, we show that these antiparasitic cardenolides can also impose significant costs on both uninfected and infected butterflies. Among eight milkweed species that vary substantially in their foliar cardenolide concentration and composition, we observed the opposing effects of cardenolides on monarch fitness traits. While high foliar cardenolide concentrations increased the tolerance of monarch butterflies to infection, they reduced the survival rate of caterpillars to adulthood. Additionally, although non-polar cardenolide compounds decreased the spore load of infected butterflies, they also reduced the life span of uninfected butterflies, resulting in a hump-shaped curve between cardenolide non-polarity and the life span of infected butterflies

  11. Radically Reducing the Costs of Panel Critical Reviews According to ISO 14040

    DEFF Research Database (Denmark)

    Weidema, Bo Pedersen; Christiansen, Kim; Wernet, Gregor

    2013-01-01

    We suggest a procedure that radically reduces the critical review costs without compromising their thoroughness and overall quality. This procedure has 3 elements: A fixed panel for all reviews, an already critically reviewed background database, and a software-supported review procedure. The pre....... The presentation discusses these elements in the light of the upcoming ISO 14071 on critical review....

  12. Texas hospitals share creative uses of non-clinical staff to reduce ER costs.

    Science.gov (United States)

    2006-01-01

    Texas hospitals share creative uses of non-clinical staff to reduce ER costs. In central Texas, Christus Spohn Hospital and Seton Health Care are independently exploring the use of non-clinical staff to improve utilization of clinical and emergency services, but their existing programs employ different structures and outcomes measurements.

  13. Development of Advanced Technologies to Reduce Design, Fabrication and Construction Costs for Future Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    DiNunzio, Camillo A. [Framatome ANP DE& S, Marlborough, MA (United States); Gupta, Abhinav [Univ. of North Carolina, Raleigh, NC (United States); Golay, Michael [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Luk, Vincent [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Turk, Rich [Westinghouse Electric Company Nuclear Systems, Windsor, CT (United States); Morrow, Charles [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jin, Geum-Taek [Korea Power Engineering Company Inc., Yongin-si, Gyeonggi-do (Korea, Republic of)

    2002-11-30

    This report presents a summation of the third and final year of a three-year investigation into methods and technologies for substantially reducing the capital costs and total schedule for future nuclear plants. In addition, this is the final technical report for the three-year period of studies.

  14. Strategies used by adults to reduce their prescription drug costs: United States, 2013.

    Science.gov (United States)

    Cohen, Robin A; Villarroel, Maria A

    2015-01-01

    Among U.S. adults aged 18-64, strategies for reducing prescription drug costs were more commonly practiced by those who were uninsured than those who had public or private coverage. Lack of health insurance coverage and poverty are recognized risk factors for not taking medication as prescribed due to cost. This cost-saving strategy may result in poorer health status and increased emergency room use and hospitalizations, compared with adults who follow their recommended pharmacotherapy. It is unknown whether adverse health outcomes and higher health care costs are also associated with the cost-reduction strategies of alternative therapy use or obtaining prescription drugs from abroad. Among adults aged 65 and over, those covered by both Medicare and Medicaid were more likely to have not taken their medication as prescribed to save money, but were less likely to have asked their doctor for a lower-cost prescription, than those who had private insurance coverage. Differences in cost-saving strategies by insurance coverage may be interrelated with socioeconomic and other patient characteristics. Belief that the recommended pharmacotherapy is needed, and an understanding of the recommended treatment, have been found to be lower among older adults who are economically vulnerable, compared with those with higher income. Income was also associated with the use of cost-reduction strategies. Among adults aged 65 and over, those living with incomes at 139%-400% FPL were more likely than adults living in lower or higher income thresholds to have asked their provider for a lower-cost prescription to save money. These patterns in the estimates by insurance status and poverty level are similar to those previously reported using the 2011 NHIS data.

  15. Reducing six-month inpatient psychiatric recidivism and costs through case management.

    Science.gov (United States)

    Kolbasovsky, Andrew; Reich, Leonard; Meyerkopf, Neil

    2010-01-01

    The objective of this study is to determine the reduction in inpatient psychiatric recidivism and costs associated with an intensive case management (ICM) program among high-risk adults with chronic mental health conditions. An intent-to-treat, historical control design was used to examine utilization differences between 306 intervention group (IG) members eligible to receive ICM services and a cohort of 290 baseline group (BG) members over a six-month outcome period. Members were identified retrospectively using identical criteria during one year prior to implementation of the program. The six-month recidivism rate for BG members was 49.67% compared to 22.07% among IG members. Forward stepwise regression results indicated a significant main effect for the ICM intervention on inpatient psychiatric costs. Inpatient psychiatric costs for the six-month outcome period were $4,982.90 lower per member in the IG group. Additional models demonstrated that the ICM intervention was associated with significantly lower inpatient substance abuse costs and psychiatric emergency department costs. There were no statistically significant increases in utilization associated with the ICM intervention. After factoring in program costs, it is estimated that the ICM services contributed to almost $1,500,000 in cost savings over the six-month outcome period. The ICM intervention was associated with significant reductions in inpatient, psychiatric six-month readmission rates and associated costs among adult members who are at elevated risk of inpatient, psychiatric recidivism. The intervention, enrollment process, and measurement strategies can be adapted for use by health plans looking to reduce psychiatric costs.

  16. Reducing door-to-needle times using Toyota's lean manufacturing principles and value stream analysis.

    Science.gov (United States)

    Ford, Andria L; Williams, Jennifer A; Spencer, Mary; McCammon, Craig; Khoury, Naim; Sampson, Tomoko R; Panagos, Peter; Lee, Jin-Moo

    2012-12-01

    Earlier tissue-type plasminogen activator (tPA) treatment for acute ischemic stroke increases efficacy, prompting national efforts to reduce door-to-needle times. We used lean process improvement methodology to develop a streamlined intravenous tPA protocol. In early 2011, a multidisciplinary team analyzed the steps required to treat patients with acute ischemic stroke with intravenous tPA using value stream analysis (VSA). We directly compared the tPA-treated patients in the "pre-VSA" epoch with the "post-VSA" epoch with regard to baseline characteristics, protocol metrics, and clinical outcomes. The VSA revealed several tPA protocol inefficiencies: routing of patients to room, then to CT, then back to the room; serial processing of workflow; and delays in waiting for laboratory results. On March 1, 2011, a new protocol incorporated changes to minimize delays: routing patients directly to head CT before the patient room, using parallel process workflow, and implementing point-of-care laboratories. In the pre and post-VSA epochs, 132 and 87 patients were treated with intravenous tPA, respectively. Compared with pre-VSA, door-to-needle times and percent of patients treated ≤60 minutes from hospital arrival were improved in the post-VSA epoch: 60 minutes versus 39 minutes (PLean process improvement methodology can expedite time-dependent stroke care without compromising safety.

  17. Micro Manufacturing

    DEFF Research Database (Denmark)

    Hansen, Hans Nørgaard

    2003-01-01

    . If a micro manufacturing system isn’t designed rationally and correctly, it will be high-cost, unreliable, and not robust. For micro products and systems it is a continuously increasing challenge to create the operational basis for an industrial production. As the products through product development...... processes are made applicable to a large number of customers, the pressure in regard to developing production technologies that make it possible to produce the products at a reasonable price and in large numbers is growing. The micro/nano manufacturing programme at the Department of Manufacturing...

  18. Can home care for homebound patients with chronic heart failure reduce hospitalizations and costs?

    Science.gov (United States)

    Punchik, Boris; Komarov, Roman; Gavrikov, Dmitry; Semenov, Anna; Freud, Tamar; Kagan, Ella; Goldberg, Yury

    2017-01-01

    Background Congestive heart failure (CHF), a common problem in adults, is associated with multiple hospitalizations, high mortality rates and high costs. Purpose To evaluate whether home care for homebound patients with CHF reduces healthcare service utilization and overall costs. Methods A retrospective study of healthcare utilization among homebound patients who received home care for CHF from 2012–1015. The outcome measures were number of hospital admissions per month, total number of hospitalization days and days for CHF only, emergency room visits, and overall costs. A comparison was conducted between the 6-month period prior to entry into home care and the time in home care. Results Over the study period 196 patients were treated by home care for CHF with a mean age of 79.4±9.5 years. 113 (57.7%) were women. Compared to the six months prior to home care, there were statistically significant decreases in hospitalizations (46.3%), in the number of total in-hospital days (28.7%), in the number of in-hospital days for CHF (66.7%), in emergency room visits (47%), and in overall costs (23.9%). Conclusion Home care for homebound adults with CHF can reduce healthcare utilization and healthcare costs. PMID:28753675

  19. IFMIF (International Fusion Materials Irradiation Facility) conceptual design activity reduced cost report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-02-01

    This report describes the results of a preliminary reevaluation of the design and cost of the International Fusion Materials Irradiation Facility (IFMIF) Project in response to the request from the 28th FPCC meeting in January 1999. Two major ideas have been considered: 1) reduction of the total construction cost through elimination of the previously planned facility upgrade and 2) a facility deployment in 3 stages with capabilities for limited experiments in the first stage. As a result, the size and complexity of the facility could be significantly reduced, leading to substantial cost savings. In addition to these two ideas, this study also included a critical review of the original CDA specification with the objective of elimination of nonessential items. For example, the number of lithium targets was reduced from two to one. As a result of these changes in addition to the elimination of the upgrade, the total cost estimate was very substantially reduced from 797.2 MICF to 487.8 MICF, where 1 MICF = 1 Million of the IFMIF Conversion Units (approximately $1M US January, 1996). (author)

  20. Increased costs reduce reciprocal helping behaviour of humans in a virtual evacuation experiment.

    Science.gov (United States)

    Bode, Nikolai W F; Miller, Jordan; O'Gorman, Rick; Codling, Edward A

    2015-11-06

    Altruistic behaviour is widespread and highly developed in humans and can also be found in some animal species. It has been suggested that altruistic tendencies can depend on costs, benefits and context. Here, we investigate the changes in the occurrence of helping behaviour in a computer-based experiment that simulates an evacuation from a building exploring the effect of varying the cost to help. Our findings illuminate a number of key mechanistic aspects of human decision-making about whether to help or not. In a novel situation where it is difficult to assess the risks associated with higher costs, we reproduce the finding that increasing costs reduce helping and find that the reduction in the frequency of helping behaviour is gradual rather than a sudden transition for a threshold cost level. Interestingly, younger and male participants were more likely to help. We provide potential explanations for this result relating to the nature of our experiment. Finally, we find no evidence that participants in our experiment plan ahead over two consecutive, inter-dependent helping opportunities when conducting cost-benefit trade-offs in spontaneous decisions. We discuss potential applications of our findings to research into decision-making during evacuations.

  1. Two ideas to increase innovation and reduce pharmaceutical costs and prices.

    Science.gov (United States)

    Jayadev, Arjun; Stiglitz, Joseph

    2009-01-01

    The pharmaceutical industry is undergoing a period of uncertainty. Profits are being squeezed by increasing costs and competitive pressures, and new drug production is slowing down. This Perspective reviews two policies that could assist in realigning incentives toward genuine innovation while also keeping drug spending growth under check. Value-based pricing can incentivize genuinely new discoveries and align research and development with social welfare. Public funding of clinical trials likewise can reduce both pharmaceutical costs and prices and direct research effort in a manner that is more socially productive than the current state of affairs.

  2. Reducing the company weighted cost-of-capital by use of Management Commentary transparency in SMEs

    DEFF Research Database (Denmark)

    Schøler, Finn

    the cost of financing through credit institutions or improve the supplier accepted creditworthiness. This paper demonstrates empirically that there is a strong relationship between corporate transparency through use of an extensive management commentary and partly the financial costs, partly creditor......In a stakeholder perspective, this paper deals with information transparency through use of the management commentary as a means to improve the relation to other stakeholders than shareholders in (smaller) non-listed companies (SME’s). Some of the main incentives for doing this could be to reduce...

  3. Installation, Operation, and Maintenance Strategies to Reduce the Cost of Offshore Wind Energy

    Energy Technology Data Exchange (ETDEWEB)

    Maples, B.; Saur, G.; Hand, M.; van de Pieterman, R.; Obdam, T.

    2013-07-01

    Currently, installation, operation, and maintenance (IO&M) costs contribute approximately 30% to the LCOE of offshore wind plants. To reduce LCOE while ensuring safety, this paper identifies principal cost drivers associated with IO&M and quantifies their impacts on LCOE. The paper identifies technology improvement opportunities and provides a basis for evaluating innovative engineering and scientific concepts developed subsequently to the study. Through the completion of a case study, an optimum IO&M strategy for a hypothetical offshore wind project is identified.

  4. Reducing the company weighted cost-of-capital by use of Management Commentary transparency in SMEs

    DEFF Research Database (Denmark)

    Schøler, Finn

    In a stakeholder perspective, this paper deals with information transparency through use of the management commentary as a means to improve the relation to other stakeholders than shareholders in (smaller) non-listed companies (SME’s). Some of the main incentives for doing this could be to reduce...... the cost of financing through credit institutions or improve the supplier accepted creditworthiness. This paper demonstrates empirically that there is a strong relationship between corporate transparency through use of an extensive management commentary and partly the financial costs, partly creditor...

  5. Installation, Operation, and Maintenance Strategies to Reduce the Cost of Offshore Wind Energy

    Energy Technology Data Exchange (ETDEWEB)

    Maples, B. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Saur, G. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hand, M. [National Renewable Energy Lab. (NREL), Golden, CO (United States); van de Pietermen, R. [Energy Research Center of the Netherlands (Netherlands); Obdam, T. [Energy Research Center of the Netherlands (Netherlands)

    2013-07-01

    Currently, installation, operation, and maintenance (IO&M) costs contribute approximately 30% to the LCOE of offshore wind plants. To reduce LCOE while ensuring safety, this paper identifies principal cost drivers associated with IO&M and quantifies their impacts on LCOE. The paper identifies technology improvement opportunities and provides a basis for evaluating innovative engineering and scientific concepts developed subsequently to the study. Through the completion of a case study, an optimum IO&M strategy for a hypothetical offshore wind project is identified.

  6. An Insurer's Care Transition Program Emphasizes Medication Reconciliation, Reduces Readmissions And Costs.

    Science.gov (United States)

    Polinski, Jennifer M; Moore, Janice M; Kyrychenko, Pavlo; Gagnon, Michael; Matlin, Olga S; Fredell, Joshua W; Brennan, Troyen A; Shrank, William H

    2016-07-01

    Adverse drug events and the challenges of clarifying and adhering to complex medication regimens are central drivers of hospital readmissions. Medication reconciliation programs can reduce the incidence of adverse drug events after discharge, but evidence regarding the impact of medication reconciliation on readmission rates and health care costs is less clear. We studied an insurer-initiated care transition program based on medication reconciliation delivered by pharmacists via home visits and telephone and explored its effects on high-risk patients. We examined whether voluntary program participation was associated with improved medication use, reduced readmissions, and savings net of program costs. Program participants had a 50 percent reduced relative risk of readmission within thirty days of discharge and an absolute risk reduction of 11.1 percent. The program saved $2 for every $1 spent. These results represent real-world evidence that insurer-initiated, pharmacist-led care transition programs, focused on but not limited to medication reconciliation, have the potential to both improve clinical outcomes and reduce total costs of care. Project HOPE—The People-to-People Health Foundation, Inc.

  7. Users guide for WoodCite, a product cost quotation tool for wood component manufacturers [computer program

    Science.gov (United States)

    Jeff Palmer; Adrienn Andersch; Jan Wiedenbeck; Urs. Buehlmann

    2014-01-01

    WoodCite is a Microsoft® Access-based application that allows wood component manufacturers to develop product price quotations for their current and potential customers. The application was developed by the U.S. Forest Service and Virginia Polytechnic Institute and State University, in cooperation with the Wood Components Manufacturers Association.

  8. "Losing ground" : Japanese labour productivity and unit laboour cost manufacturing in comparison to the U.S.

    NARCIS (Netherlands)

    Inklaar, Robert; Wu, Harry; Ark, Bart van

    2003-01-01

    This paper looks at several measures of competitiveness for the Japanese manufacturing sector relative to the United States over the period 1980-2000. Using industry-specific unit-value ratios (UVRs) we show that labour productivity in Japanese manufacturing lags considerably behind the U.S. and

  9. Income Tax Returns: Reducing Compliance Costs for Personal Income Taxpayers in Slovenia

    Directory of Open Access Journals (Sweden)

    Maja Klun

    2009-06-01

    Full Text Available Simplifying procedures and improving legislation generally lead to a reduction in the compliance costs. The introduction of pre-filled tax returns clearly simplifies the tax compliance procedure. Before the introduction of pre-filled tax returns for personal income taxpayers in Slovenia, tax legislation was also modified. This paper presents the results of research into the compliance costs for personal income taxpayers before and after the simplification of the compliance procedure in Slovenia, irrespective of tax legislation itself not being simplified. The results indicate that pre-filled tax returns reduce compliance costs for personal income taxpayers by around 73%. Nevertheless, this is only a tentative estimate, since several assumptions are taken into account.

  10. Reducing Inbound Logistics Costs- A Case Study in the Chinese Automobile Industry

    OpenAIRE

    Feng, Mengying

    2006-01-01

    Globalization has made company competition more intense. Supply chain management has developed to enable companies to compete effectively. Logistics supports competitiveness of the supply chain as a whole by meeting customer demand both timely and at a competitive cost and inbound logistics cost management is considered to be a priority in reducing costs. As the Chinese automobile industry is ChinaÃ�Æ�Ã�Æ�Ã�â��Ã�Æ�Ã�Æ�Ã�â��Ã�â��Ã�¢Ã�Æ�Ã�Æ�Ã�â��Ã�â��Ã�Æ�Ã�â��Ã�â��Ã�â�¬Ã�Æ�Ã�Æ�Ã�â��Ã�â��Ã...

  11. Reducing Health Cost: Health Informatics and Knowledge Management as a Business and Communication Tool

    Science.gov (United States)

    Gyampoh-Vidogah, Regina; Moreton, Robert; Sallah, David

    Health informatics has the potential to improve the quality and provision of care while reducing the cost of health care delivery. However, health informatics is often falsely regarded as synonymous with information management (IM). This chapter (i) provides a clear definition and characteristic benefits of health informatics and information management in the context of health care delivery, (ii) identifies and explains the difference between health informatics (HI) and managing knowledge (KM) in relation to informatics business strategy and (iii) elaborates the role of information communication technology (ICT) KM environment. This Chapter further examines how KM can be used to improve health service informatics costs, and identifies the factors that could affect its implementation and explains some of the reasons driving the development of electronic health record systems. This will assist in avoiding higher costs and errors, while promoting the continued industrialisation of KM delivery across health care communities.

  12. Role of geothermal reservoir engineering in reducing costs per kilowatt-hour

    Energy Technology Data Exchange (ETDEWEB)

    Pritchett, J.W. [Maxwell Technologies, San Diego, CA (United States)

    1997-12-31

    Reservoir characterization and monitoring constitute small but finite components of the total cost of geothermal power, and also have substantial implications for overall cost reduction. There are at least three roles which reservoir engineering can play in improving the competitive position of the geothermal power industry. First, techniques are now being developed which will reduce the costs associated with the early part of field characterization--after the resource has been tentatively identified, but prior to exploitation. For example, the use of slimholes for exploration and preliminary assessment offers major cost savings compared to conventional drilling practice. Slim holes drilled originally for exploration may also serve as monitor wells during production. Second, using unconventional measurements (usually associated with exploration) for reservoir monitoring will substantially improve the reliability of reservoir models by providing more data for history-matching as the reservoir is exploited. Although not yet in routine use, surface microgravity changes have long been known to provide insights into quantity and character of reservoir recharge. Changes in electrical measurements (including self-potential and resistivity) and possibly even seismic techniques also appear promising. Improving the understanding of events which are actually taking place under-ground during field production will permit the development of improved exploitation strategies, reducing the need for makeup drilling, postponing or avoiding cold-water invasion of production wells, and prolonging reservoir life.

  13. Cost/benefit tradeoffs for reducing the energy consumption of the commercial air transportation system

    Science.gov (United States)

    Kraus, E. F.; Vanabkoude, J. C.

    1976-01-01

    The fuel saving potential and cost effectiveness of numerous operational and technical options proposed for reducing the fuel consumption of the U.S. commercial airline fleet was examined and compared. The impact of the most promising fuel conserving options on fuel consumption, passenger demand, operating costs and airline profits when implemented in the U.S. domestic and international airline fleets was determined. A forecast estimate was made of the potential fuel savings achievable in the U.S. scheduled air transportation system. Specifically, the means for reducing the jet fuel consumption of the U.S. scheduled airlines in domestic and international passenger operations were investigated. A design analysis was made of two turboprop aircraft as possible fuel conserving derivatives of the DC-9-30.

  14. A comparison of response cost and differential reinforcement of other behavior to reduce disruptive behavior in a preschool classroom.

    Science.gov (United States)

    Conyers, Carole; Miltenberger, Raymond; Maki, Amber; Barenz, Rebecca; Jurgens, Mandy; Sailer, Angela; Haugen, Meredith; Kopp, Brandon

    2004-01-01

    This study investigated the effectiveness of response cost and differential reinforcement of other behavior (DRO) in reducing the disruptive behaviors of 25 children in a preschool classroom. Using an alternating treatments design, disruptive behavior was reduced when the participants earned tokens for the absence of disruptive behavior (DRO) or lost tokens for the occurrence of disruptive behavior (response cost). Initially, DRO was more successful in reducing the number of disruptive behaviors; however, over time, response cost proved to be more effective.

  15. Test sequencing problem arising at the design stage for reducing life cycle cost

    Institute of Scientific and Technical Information of China (English)

    Zhang Shigang; Hu Zheng; Wen Xisen

    2013-01-01

    Previous test sequencing algorithms only consider the execution cost of a test at the application stage.Due to the fact that the placement cost of some tests at the design stage is considerably high compared with the execution cost,the sequential diagnosis strategy obtained by previous methods is actually not optimal from the view of life cycle.In this paper,the test sequencing problem based on life cycle cost is presented.It is formulated as an optimization problem,which is non-deterministic polynomial-time hard (NP-hard).An algorithm and a strategy to improve its computational efficiency are proposed.The formulation and algorithms are tested on various simulated systems and comparisons are made with the extant test sequencing methods.Application on a pump rotational speed control (PRSC) system of a spacecraft is studied in detail.Both the simulation results and the real-world case application results suggest that the solution proposed in this paper can significantly reduce the life cycle cost of a sequential fault diagnosis strategy.

  16. Marketplace Subsidies: Changing The 'Family Glitch' Reduces Family Health Spending But Increases Government Costs.

    Science.gov (United States)

    Buettgens, Matthew; Dubay, Lisa; Kenney, Genevieve M

    2016-07-01

    Under the Affordable Care Act, if one family member has an employer offer of single coverage deemed to be affordable-that is, costing less than 9.66 percent of family income in 2016-then all family members are ineligible for tax credits for Marketplace coverage, even if the cost of providing coverage to the whole family is greater than 9.66 percent of income. More than six million people live in such families and as a result are ineligible for premium tax credits. These families face premiums that can amount to 15.8 percent of income, or 12.0 percent after the tax advantages of employer-sponsored health coverage are factored in. We modeled the potential impact of changing the affordability test to take into account the cost of family coverage. Doing so would reduce spending on premiums from 12.0 percent to 6.3 percent of income, significantly alleviating financial burdens, but would generate little additional coverage. We estimated the additional costs to the federal government for premium tax credits and cost-sharing reductions to be between $3.7 billion and $6.5 billion in 2016.

  17. A female-biased sex ratio reduces the twofold cost of sex

    Science.gov (United States)

    Kobayashi, Kazuya; Hasegawa, Eisuke

    2016-04-01

    The evolution of sexual reproduction remains a fascinating enigma in biology. Theoretically, populations of sexual organisms investing half of their resources into producing male offspring that don’t contribute to reproduction should grow at only half the rate of their asexual counterparts. This demographic disadvantage due to male production is known as the twofold cost of sex. However, the question of whether this cost is truly twofold for sexual females remains unanswered. The cost of producing males should decrease when the number of male offspring is reduced. Here, we report a case where the cost of males is actually less than twofold. By measuring the numbers of sexual strain coexisting with asexual strain among thrips, our survey revealed that the sexual strain showed female-biased sex ratios and that the relative frequency of sexual strain is negatively correlated with the proportion of males in the sexual strain. Using computer simulations, we confirmed that a female-biased sex ratio evolves in sexual individuals due to the coexistence of asexual individuals. Our results demonstrate that there is a cost of producing males that depends on the number of males. We therefore conclude that sexual reproduction can evolve with far fewer benefits than previously assumed.

  18. Root phenes that reduce the metabolic costs of soil exploration: opportunities for 21st century agriculture.

    Science.gov (United States)

    Lynch, Jonathan P

    2015-09-01

    Crop genotypes with reduced metabolic costs of soil exploration would have improved water and nutrient acquisition. Three strategies to achieve this goal are (1) production of the optimum number of axial roots; (2) greater biomass allocation to root classes that are less metabolically demanding; and (3) reduction of the respiratory requirement of root tissue. An example of strategy 1 is the case of reduced crown root number in maize, which is associated with greater rooting depth, N capture and yield in low N soil. An example of strategy 2 is the case of increased hypocotyl-borne rooting in bean, which decreases root cost and increases P capture from low P soil. Examples of strategy 3 are the cases of increased formation of root cortical aerenchyma, decreased cortical cell file number and increased cortical cell size in maize, which decrease specific root respiration, increase rooting depth and increase water capture and yield under water stress. Root cortical aerenchyma also increases N capture and yield under N stress. Root phenes that reduce the metabolic cost of soil exploration are promising, underexploited avenues to the climate-resilient, resource-efficient crops that are urgently needed in global agriculture.

  19. Low-Cost, Class D Testing of Spacecraft Photovoltaic Systems Can Reduce Risk

    Science.gov (United States)

    Forgione, Joshua B.; Kojima, Gilbert K.; Hanel, Robert; Mallinson, Mark V.

    2014-01-01

    The end-to-end verification of a spacecraft photovoltaic power generation system requires light! Specifically, the standard practice for doing so is the Large Area Pulsed Solar Simulation (LAPSS). A LAPSS test can characterize a photovoltaic system's efficiency via its response to rapidly applied impulses of simulated sunlight. However, a Class D program on a constrained budget and schedule may not have the resources to ship an entire satellite for a LAPSS test alone. Such was the case with the Lunar Atmospheric and Dust Environment Explorer (LADEE) program, which was also averse to the risk of hardware damage during shipment. When the Electrical Power System (EPS) team was denied a spacecraft-level LAPSS test, the lack of an end-to-end power generation test elevated to a project-level technical risk. The team pulled together very limited resources to not only eliminate the risk, but build a process to monitor the health of the system through mission operations. We discuss a process for performing a low-cost, end-to-end test of the LADEE photovoltaic system. The approach combines system-level functional test, panel-level performance results, and periodic inspection (and repair) up until launch. Following launch, mission operations tools are utilized to assess system performance based on a scant amount of data. The process starts in manufacturing at the subcontractor. The panel manufacturer provides functional test and LAPSS data on each individual panel. We apply an initial assumption that the per-panel performance is sufficient to meet the power generation requirements. The manufacturer's data is also carried as the performance allocation for each panel during EPS system modeling and initial mission operations. During integration and test, a high-power, professional theater lamp system provides simulated sunlight to each panel on the spacecraft, thereby permitting a true end-to-end system test. A passing test results in a step response to nearly full-rated current

  20. Photovoltaic Manufacturing Technology, Phase 1, Final report

    Energy Technology Data Exchange (ETDEWEB)

    Easoz, J.R.; Herlocher, R.H. (Westinghouse Electric Corp., Pittsburgh, PA (United States))

    1991-12-01

    This report examines the cost-effective manufacture of dendritic-web-based photovoltaic modules. It explains how process changes can increase production and reduce manufacturing costs. Long-range benefits of these improved processes are also discussed. Problems are identified that could impede increasing production and reducing costs; approaches to solve these problems are presented. These approaches involve web growth throughput, cell efficiency, process yield, silicon use, process control, automation, and module efficiency. Also discussed are the benefits of bifacial module design, unique to the dendritic web process.

  1. Make or Buy: Cost Impacts of Additive Manufacturing, 3D Laser Scanning Technology, and Collaborative Product Lifecycle Management on Ship Maintenance and Modernization

    Science.gov (United States)

    2015-05-01

    1 Make or Buy: Cost Impacts of Additive Manufacturing, 3D Laser Scanning Technology, and Collaborative Product Lifecycle Management on Ship...and Collaborative Product Lifecycle Management on Ship Maintenance and Modernization 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER...plants 3 Potential Technology 2: Collaborative Product Lifecycle Management • To “integrate people, processes, and information” • Electronically

  2. Final Rule to Reduce Toxic Air Emissions from Asphalt Processing and Asphalt Roofing Manufacturing Facilities Fact Sheet

    Science.gov (United States)

    This page contains a February 2003 fact sheet with information regarding the National Emissions Standards for Hazardous Air Pollutants (NESHAP) for Asphalt Processing and Asphalt Roofing Manufacturing.

  3. Micro Manufacturing

    DEFF Research Database (Denmark)

    Hansen, Hans Nørgaard

    2003-01-01

    Manufacturing deals with systems that include products, processes, materials and production systems. These systems have functional requirements, constraints, design parameters and process variables. They must be decomposed in a systematic manner to achieve the best possible system performance....... If a micro manufacturing system isn’t designed rationally and correctly, it will be high-cost, unreliable, and not robust. For micro products and systems it is a continuously increasing challenge to create the operational basis for an industrial production. As the products through product development...... processes are made applicable to a large number of customers, the pressure in regard to developing production technologies that make it possible to produce the products at a reasonable price and in large numbers is growing. The micro/nano manufacturing programme at the Department of Manufacturing...

  4. Labor compensation,labor productivity and labor cost advantage—An empirical study of Chinese manufacturing enterprises during 2000-2007

    Institute of Scientific and Technical Information of China (English)

    都阳; 曲玥

    2009-01-01

    Unlike the usual practice of equating wages or labor compensation with labor cost,this paper incorporates labor productivity into an analytical framework and holds that the labor cost advantage is the relative relationship between labor compensation and labor productivity.Based on an empirical study of the data of Chinese manufacturing firms that include all state-owned enterprises and non-state-owned enterprises with their annual revenue greater than 5 million yuan from 2000 to 2007,this paper finds that labor compensation growth was accompanied by faster labor productivity growth.Hence,the labor cost advantage was not weakened during this period.Furthermore,this paper conducts an exploration of how to sustain labor cost advantages in the future and proposes that they can be sustained by upgrading the industrial structure and improving the education system.

  5. A multidisciplinary approach to reducing alarm fatigue and cost through appropriate use of cardiac telemetry.

    Science.gov (United States)

    Alsaad, Ali A; Alman, Carly R; Thompson, Kristine M; Park, Shin H; Monteau, Rebecca E; Maniaci, Michael J

    2017-07-01

    Alarm fatigue (AF) is a distressing factor for staff and patients in the hospital. Using cardiac telemetry (CT) without clinical indications can create unnecessary alarms, and increase AF and cost of healthcare. We sought to reduce AF and cost associated with CT monitoring. After implementing a new protocol for CT placement, data were collected on telemetry orders, alarms and bed cost for 13 weeks from 1 January 2015 through 31 March 2015. We also retrospectively collected data on the same variables for the 13 weeks prior to the intervention. A survey was administered to nurses to assess past and present perceptions of AF. Interventions included protocol creation and education for participants. At baseline, 77% of patients were monitored with CT. A total of 145 (31%) order discrepancies were discovered during data collection, of which 72% had no indication for CT, so CT was discontinued. The other 28% had indications, so orders were placed. A total of 8336 alarms were recorded during 4 weeks of data collection, of which 333 (4%) were classified as true actionable alarms. Postintervention data showed 67% CT assignment with 10% reduction in CT usage, with no increase in mortality (p0.05, respectively). A 42% cost reduction was achieved after adjusting the patient status. Nurses reported 27% perceived reduction in AF. One-year follow-up revealed that 69% of patients were being monitored by CT, and the rate of order discrepancies due to lack of indication was 9%. All hospital units may benefit from the protocols created during this study. If applied appropriately, these protocols can lead to reduced AF and cost per episode of care. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  6. Building Commissioning: A Golden Opportunity for Reducing Energy Costs and Greenhouse-gas Emissions

    Energy Technology Data Exchange (ETDEWEB)

    Mills, Evan

    2009-07-16

    data are available revealed over 10,000 energy-related problems, resulting in 16% median whole-building energy savings in existing buildings and 13% in new construction, with payback time of 1.1 years and 4.2 years, respectively. In terms of other cost-benefit indicators, median benefit-cost ratios of 4.5 and 1.1, and cash-on-cash returns of 91% and 23% were attained for existing and new buildings, respectively. High-tech buildings were particularly cost-effective, and saved higher amounts of energy due to their energy-intensiveness. Projects with a comprehensive approach to commissioning attained nearly twice the overall median level of savings and five-times the savings of the least-thorough projects. It is noteworthy that virtually all existing building projects were cost-effective by each metric (0.4 years for the upper quartile and 2.4 years for the lower quartile), as were the majority of new-construction projects (1.5 years and 10.8 years, respectively). We also found high cost-effectiveness for each specific measure for which we have data. Contrary to a common perception, cost-effectiveness is often achieved even in smaller buildings. Thanks to energy savings valued more than the cost of the commissioning process, associated reductions in greenhouse gas emissions come at 'negative' cost. In fact, the median cost of conserved carbon is negative - -$110 per tonne for existing buildings and -$25/tonne for new construction - as compared with market prices for carbon trading and offsets in the +$10 to +$30/tonne range. Further enhancing the value of commissioning, its non-energy benefits surpass those of most other energy-management practices. Significant first-cost savings (e.g., through right-sizing of heating and cooling equipment) routinely offset at least a portion of commissioning costs - fully in some cases. When accounting for these benefits, the net median commissioning project cost was reduced by 49% on average, while in many cases they exceeded

  7. A New Method for Low Cost Production of Titanium Alloys for Reducing Energy Consumption of Mechanical Systems

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Z. Zak [Univ. of Utah, Salt Lake City, UT (United States); Chandran, Ravi [Univ. of Utah, Salt Lake City, UT (United States); Koopman, Mark [Univ. of Utah, Salt Lake City, UT (United States)

    2016-02-29

    This project investigated an innovative manufacturing process intended to minimize the cost of production of titanium materials and components, and increase the adoption of Ti components for energy consuming applications, such as automobiles. A key innovation of the proposed manufacturing approach is a novel Ti powder sintering technology for making titanium materials with ultrafine grain microstructure in the as-sintered state with minimum, or an absence, of post-sintering processes. The new sintering technology is termed Hydrogen Sintering and Phase Transformations (HSPT), and constitutes a promising manufacturing technology that can be used to produce titanium (Ti) materials and components in a near-net-shape form, thus also minimizing machining costs. Our objective was to meet, or possibly surpass, the mechanical property levels for ASTM B348 Grade 5 for wrought Ti-6Al-4V. Although specific applications call for varying mechanical property requirements, ASTM B348 was created for the demanding applications of the aerospace industry, and is the established standard for Ti-6Al-4V. While the primary goal was to meet, or exceed this standard, the team also had the goal of demonstrating this could be done at a significantly lower cost of production. Interim goals of the project were to fully develop this novel sintering process, and provide sufficient baseline testing to make the method practical and attractive to industry. By optimizing the process parameters for the sintering of titanium hydride (TiH2) powders in a hydrogen atmosphere and controlling the phase transformations during and after sintering, the HSPT process was expected to reduce the energy consumption, and thus cost, of making Ti alloys and fabricating Ti components. The process was designed such that no high temperature melting is required for producing Ti alloys; little or no post-sintering processing is needed for producing desired microstructures (and therefore enhanced mechanical

  8. Reduced cost alternatives to premise wiring using ATM and microcellular technologies

    Science.gov (United States)

    Gejji, Raghvendra R.

    1993-01-01

    The cost of premises wiring keeps increasing due to personnel moves, new equipment, capacity upgrades etc. It would be desirable to have a wireless interface from the workstations to the fixed network, so as to minimize the wiring changes needed. New technologies such as microcellular personal communication systems are promising to bring down the cost of wireless communication. Another promising technology is Code Division Multiple Access (CDMA), which could dramatically increase the bandwidth available for wireless connections. In addition, Asynchronous Transfer Mode (ATM) technology is emerging as a technique for integrated management of voice, data, and video traffic on a single network. The focus of this investigation will be to assess the future utility of these new technologies for reducing the premise wiring cost at KSC. One of the issues to be studied is the cost comparison of 'old' versus 'new,' especially as time and technology progress. An additional issue for closer study is a feasible time-line for progress in technological capability.

  9. Reducing annotation cost and uncertainty in computer-aided diagnosis through selective iterative classification

    Science.gov (United States)

    Riely, Amelia; Sablan, Kyle; Xiaotao, Thomas; Furst, Jacob; Raicu, Daniela

    2015-03-01

    Medical imaging technology has always provided radiologists with the opportunity to view and keep records of anatomy of the patient. With the development of machine learning and intelligent computing, these images can be used to create Computer-Aided Diagnosis (CAD) systems, which can assist radiologists in analyzing image data in various ways to provide better health care to patients. This paper looks at increasing accuracy and reducing cost in creating CAD systems, specifically in predicting the malignancy of lung nodules in the Lung Image Database Consortium (LIDC). Much of the cost in creating an accurate CAD system stems from the need for multiple radiologist diagnoses or annotations of each image, since there is rarely a ground truth diagnosis and even different radiologists' diagnoses of the same nodule often disagree. To resolve this issue, this paper outlines an method of selective iterative classification that predicts lung nodule malignancy by using multiple radiologist diagnoses only for cases that can benefit from them. Our method achieved 81% accuracy while costing only 46% of the method that indiscriminately used all annotations, which achieved a lower accuracy of 70%, while costing more.

  10. Reduced metabolic cost of locomotion in Svalbard rock ptarmigan (Lagopus muta hyperborea during winter.

    Directory of Open Access Journals (Sweden)

    John Lees

    Full Text Available The Svalbard rock ptarmigan, Lagopus muta hyperborea experiences extreme photoperiodic and climatic conditions on the Arctic archipelago of Svalbard. This species, however, is highly adapted to live in this harsh environment. One of the most striking adaptations found in these birds is the deposition, prior to onset of winter, of fat stores which may comprise up to 32% of body mass and are located primarily around the sternum and abdominal region. This fat, while crucial to the birds' survival, also presents a challenge in that the bird must maintain normal physiological function with this additional mass. In particular these stores are likely to constrain the respiratory system, as the sternum and pelvic region must be moved during ventilation and carrying this extra load may also impact upon the energetic cost of locomotion. Here we demonstrate that winter birds have a reduced cost of locomotion when compared to summer birds. A remarkable finding given that during winter these birds have almost twice the body mass of those in summer. These results suggest that Svalbard ptarmigan are able to carry the additional winter fat without incurring any energetic cost. As energy conservation is paramount to these birds, minimising the costs of moving around when resources are limited would appear to be a key adaptation crucial for their survival in the barren Arctic environment.

  11. Costs of reducing water use of concentrating solar power to sustainable levels: Scenarios for North Africa

    Energy Technology Data Exchange (ETDEWEB)

    Damerau, Kerstin, E-mail: damerau@iiasa.ac.at [International Institute for Applied Systems Analysis (Austria); Williges, Keith; Patt, Anthony G. [International Institute for Applied Systems Analysis (Austria); Gauche, Paul [Department of Mechanical and Mechatronic Engineering, Stellenbosch University (South Africa)

    2011-07-15

    Concentrating solar power (CSP) has the potential to become a leading sustainable energy technology for the European electricity system. In order to reach a substantial share in the energy mix, European investment in CSP appears most profitable in North Africa, where solar potential is significantly higher than in southern Europe. As well as sufficient solar irradiance, however, the majority of today's CSP plants also require a considerable amount of water, primarily for cooling purposes. In this paper we examine water usage associated with CSP in North Africa, and the cost penalties associated with technologies that could reduce those needs. We inspect four representative sites to compare the ecological and economical drawbacks from conventional and alternative cooling systems, depending on the local environment, and including an outlook with climate change to the mid-century. Scaling our results up to a regional level indicates that the use of wet cooling technologies would likely be unsustainable. Dry cooling systems, as well as sourcing of alternative water supplies, would allow for sustainable operation. Their cost penalty would be minor compared to the variance in CSP costs due to different average solar irradiance values. - Highlights: > Scaling up CSP with wet cooling from ground water will be unsustainable in North Africa. > Desalination and alternative cooling systems can assure a sustainable water supply. > On large-scale, the cost penalties of alternative cooling technologies appear minor.

  12. Estimating Potential and Costs of Reducing CO2 Emissions in Lithuanian Buildings

    Directory of Open Access Journals (Sweden)

    Eglė Jaraminienė

    2012-03-01

    Full Text Available The EU is considering increasing the GHG emissions reduction target by 2020 from 20% to 30% by committing each member state to tighten up its emission reduction goals. According to the recent study such decision could cost some 2 365 million LTL to Lithuanian economy. Evaluation and comparison of CO2 abatement costs incurred by the state implementing a variety of measures in different sectors allow choosing a most cost effective policy scenario. The paper focuses on CO2 emissions related to energy use in buildings. First, this paper reviews the role of the Lithuanian building stock in overall GHG emissions. Then the paper examines the existing studies on the CO2 mitigation potential and cost in buildings. Given the limitations of existing evaluation and lack of comprehensive modelling in the existing studies, this paper proposes a framework for examining the technology options aimed to inform policy making on the options to reduce CO2 emissions in Lithuanian housing and service sectors.DOI: http://dx.doi.org/10.5755/j01.erem.59.1.680

  13. Evaluation of a Reduced Cost Active NDVI Sensor for Crop Nutrient Management

    Directory of Open Access Journals (Sweden)

    Jared Crain

    2012-01-01

    Full Text Available There are methods to increase fertilizer nitrogen use efficiency through optical sensor-based nitrogen application; however, the sensors are expensive and cost prohibitive to farmers in the developing world. This study evaluated a novel, reduced cost, prototype, and optical sensor to determine if it could be used with the same level of accuracy as a commercial sensor. The stability of the prototype sensor (pocket sensor to maintain an accurate calibration over time, the effect of operator on sensor readings, and sensor performance in maize and wheat were assessed. Evaluation of the sensor performance was conducted in existing wheat and maize trials, as well as turf grass canopies at the International Maize and Wheat Improvement Center, Ciudad Obregon, Mexico.The prototype sensors were highly correlated to the commercial GreenSeeker NDVI sensor in turf grass, wheat, and maize canopies (r2>0.97, r2>0.95, and r2>0.91, resp.. The Pocket Sensors lacked some precision in comparison to the commercial sensor; however, even with the reduced precision, the cost of the sensor and robustness of N fertilizer algorithms compensate for this apparent weakness. The pocket sensor is a new and viable tool to assess wheat and maize nitrogen status and make nitrogen recommendations based upon the data collected with this sensor.

  14. Comparing climate and cost impacts of reference levels for reducing emissions from deforestation

    Energy Technology Data Exchange (ETDEWEB)

    Busch, Jonah [Center for Applied Biodiversity Science, Conservation International, 2011 Crystal Drive, Suite 500, Arlington, VA (United States); Strassburg, Bernardo [Center for Social and Economic Research on the Global Environment, University of East Anglia, Norwich NR4 7TJ (United Kingdom); Cattaneo, Andrea [Woods Hole Research Center, 149 Woods Hole Road, Falmouth, MA 02540-1644 (United States); Lubowski, Ruben [Environmental Defense Fund, 1875 Connecticut Avenue NW, Washington, DC (United States); Bruner, Aaron; Rice, Richard; Boltz, Frederick [Conservation International, 2011 Crystal Drive, Suite 500, Arlington, VA (United States); Creed, Anna; Ashton, Ralph, E-mail: jbusch@conservation.or [Terrestrial Carbon Group, 900 17th Street NW, Suite 700, Washington, DC (United States)

    2009-10-15

    The climate benefit and economic cost of an international mechanism for reducing emissions from deforestation and degradation (REDD) will depend on the design of reference levels for crediting emission reductions. We compare the impacts of six proposed reference level designs on emission reduction levels and on cost per emission reduction using a stylized partial equilibrium model (the open source impacts of REDD incentives spreadsheet; OSIRIS). The model explicitly incorporates national incentives to participate in an international REDD mechanism as well as international leakage of deforestation emissions. Our results show that a REDD mechanism can provide cost-efficient climate change mitigation benefits under a broad range of reference level designs. We find that the most effective reference level designs balance incentives to reduce historically high deforestation emissions with incentives to maintain historically low deforestation emissions. Estimates of emission reductions under REDD depend critically on the degree to which demand for tropical frontier agriculture generates leakage. This underscores the potential importance to REDD of complementary strategies to supply agricultural needs outside of the forest frontier.

  15. THE ROLE OF TIPPING IN REDUCING LABOUR COSTS: CASE OF SECTOR RETAIL PETROLEUM PRODUCTS

    Directory of Open Access Journals (Sweden)

    Andrej Raspor

    2014-05-01

    Full Text Available The purpose of this paper was to determine whether tipping could reduce labour costs in the petroleum products retail sector. The research we present was designed on the basis of survey results gathered from Slovenian petrol stations in 2009 and 2010. We have identified the following factors in the tipping process: job satisfaction, flexibility, service quality, satisfaction, motivation and the factor of receiving tips. The analysis showed correlation between methods used to increase the value of tips and better service quality, increased financial and numerical flexibility, motivation, satisfaction upon receipt of tips and the method used to increase the value of tips. In order to decrease labour costs we propose that the management take control of tipping and integrates tips into the reward system. Also, the employees should be made aware about how tipping improves service and increases their income.

  16. The role of technology in reducing health care costs. Final project report

    Energy Technology Data Exchange (ETDEWEB)

    Sill, A.E.; Warren, S.; Dillinger, J.D.; Cloer, B.K.

    1997-08-01

    Sandia National Laboratories applied a systems approach to identifying innovative biomedical technologies with the potential to reduce U.S. health care delivery costs while maintaining care quality. This study was conducted by implementing both top-down and bottom-up strategies. The top-down approach used prosperity gaming methodology to identify future health care delivery needs. This effort provided roadmaps for the development and integration of technology to meet perceived care delivery requirements. The bottom-up approach identified and ranked interventional therapies employed in existing care delivery systems for a host of health-related conditions. Economic analysis formed the basis for development of care pathway interaction models for two of the most pervasive, chronic disease/disability conditions: coronary artery disease (CAD) and benign prostatic hypertrophy (BPH). Societal cost-benefit relationships based on these analyses were used to evaluate the effect of emerging technology in these treatment areas. 17 figs., 48 tabs.

  17. Using Biomass as Fuel Substitute to Reduce Fuel Cost in Locomotive

    Directory of Open Access Journals (Sweden)

    Gunjan De

    2013-10-01

    Full Text Available The biological waste poses some characteristics which indicate that they have the calorific value up to some extent which can be used as a fuel. Jute sticks, Jute caddies, cow dung dust, Dhaincha stick, wood etc. can be used as a raw material. By application of proper technologies the potential of these materials can be exploited. The study will show that the one ton of any of these bio wastes can easily substitute coal and oil which will also reduce the fuel cost as well. The process implies supply of producer gas from gasifier to engine to generate power in space of diesel engine to run locomotives, in industries, in power generation, etc. This will result in utilization of green energy and cost effective operation.

  18. Crime and punishment. Can the NHIN reduce the cost of healthcare fraud?

    Science.gov (United States)

    Parente, Stephen T; Mandelbaum, Karen; Hanson, Susan P; Cassidy, Bonnie S; Simborg, Donald W

    2008-01-01

    In his 2004 State of the Union Address, President Bush called for the adoption of the electronic health record (EHR) to increase efficiency and improve the quality of healthcare. This system could reduce healthcare costs by 20 percent or more per year. Some of those savings would be attributed to a dramatic reduction in losses due to fraud. Though IT by itself cannot solve the problem of healthcare fraud, developing an interoperable National Health Information Network (NHIN) can provide a platform to implement real-time anti-fraud controls. In this paper we inventory the costs and benefits of fraud detection from the NHIN and conclude that such an infrastructure investment has the potential to produce significant national savings.

  19. What Strategies Do Physicians and Patients Discuss to Reduce Out-of-Pocket Costs? Analysis of Cost-Saving Strategies in 1,755 Outpatient Clinic Visits.

    Science.gov (United States)

    Hunter, Wynn G; Zhang, Cecilia Z; Hesson, Ashley; Davis, J Kelly; Kirby, Christine; Williamson, Lillie D; Barnett, Jamison A; Ubel, Peter A

    2016-10-01

    More than 1 in 4 Americans report difficulty paying medical bills. Cost-reducing strategies discussed during outpatient physician visits remain poorly characterized. We sought to determine how often patients and physicians discuss health care costs during outpatient visits and what strategies, if any, they discussed to lower patient out-of-pocket costs. Retrospective analysis of dialogue from 1,755 outpatient visits in community-based practices nationwide from 2010 to 2014. The study population included 677 patients with breast cancer, 422 with depression, and 656 with rheumatoid arthritis visiting 56 oncologists, 36 psychiatrists, and 26 rheumatologists, respectively. Thirty percent of visits contained cost conversations (95% confidence interval [CI], 28 to 32). Forty-four percent of cost conversations involved discussion of cost-saving strategies (95% CI, 40 to 48; median duration, 68 s). We identified 4 strategies to lower costs without changing the care plan. They were, in order of overall frequency: 1) changing logistics of care, 2) facilitating co-pay assistance, 3) providing free samples, and 4) changing/adding insurance plans. We also identified 4 strategies to reduce costs by changing the care plan: 1) switching to lower-cost alternative therapy/diagnostic, 2) switching from brand name to generic, 3) changing dosage/frequency, and 4) stopping/withholding interventions. Strategies were relatively consistent across health conditions, except for switching to a lower-cost alternative (more common in breast oncology) and providing free samples (more common in depression). Focus on 3 conditions with potentially high out-of-pocket costs. Despite price opacity, physicians and patients discuss a variety of out-of-pocket cost reduction strategies during clinic visits. Almost half of cost discussions mention 1 or more cost-saving strategies, with more frequent mention of those not requiring care-plan changes. © The Author(s) 2016.

  20. Costs and cost-effectiveness of training traditional birth attendants to reduce neonatal mortality in the Lufwanyama Neonatal Survival study (LUNESP.

    Directory of Open Access Journals (Sweden)

    Lora L Sabin

    Full Text Available BACKGROUND: The Lufwanyama Neonatal Survival Project ("LUNESP" was a cluster randomized, controlled trial that showed that training traditional birth attendants (TBAs to perform interventions targeting birth asphyxia, hypothermia, and neonatal sepsis reduced all-cause neonatal mortality by 45%. This companion analysis was undertaken to analyze intervention costs and cost-effectiveness, and factors that might improve cost-effectiveness. METHODS AND FINDINGS: We calculated LUNESP's financial and economic costs and the economic cost of implementation for a forecasted ten-year program (2011-2020. In each case, we calculated the incremental cost per death avoided and disability-adjusted life years (DALYs averted in real 2011 US dollars. The forecasted 10-year program analysis included a base case as well as 'conservative' and 'optimistic' scenarios. Uncertainty was characterized using one-way sensitivity analyses and a multivariate probabilistic sensitivity analysis. The estimated financial and economic costs of LUNESP were $118,574 and $127,756, respectively, or $49,469 and $53,550 per year. Fixed costs accounted for nearly 90% of total costs. For the 10-year program, discounted total and annual program costs were $256,455 and $26,834 respectively; for the base case, optimistic, and conservative scenarios, the estimated cost per death avoided was $1,866, $591, and $3,024, and cost per DALY averted was $74, $24, and $120, respectively. Outcomes were robust to variations in local costs, but sensitive to variations in intervention effect size, number of births attended by TBAs, and the extent of foreign consultants' participation. CONCLUSIONS: Based on established guidelines, the strategy of using trained TBAs to reduce neonatal mortality was 'highly cost effective'. We strongly recommend consideration of this approach for other remote rural populations with limited access to health care.

  1. Low Cost Automated Manufacture of High Efficiency THINS ZTJ PV Blanket Technology (P-NASA12-007) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA needs lower cost solar arrays with high performance for a variety of missions. While high efficiency, space-qualified solar cells are in themselves costly, >...

  2. Photovoltaic manufacturing technology, Phase 1

    Energy Technology Data Exchange (ETDEWEB)

    1992-10-01

    This report describes subcontracted research by the Chronar Corporation, prepared by Advanced Photovoltaic Systems, Inc. (APS) for Phase 1 of the Photovoltaic Manufacturing Technology Development project. Amorphous silicon is chosen as the PV technology that Chronar Corporation and APS believe offers the greatest potential for manufacturing improvements, which, in turn, will result in significant cost reductions and performance improvements in photovoltaic products. The APS Eureka'' facility was chosen as the manufacturing system that can offer the possibility of achieving these production enhancements. The relationship of the Eureka'' facility to Chronar's batch'' plants is discussed. Five key areas are also identified that could meet the objectives of manufacturing potential that could lead to improved performance, reduced manufacturing costs, and significantly increased production. The projected long-term potential benefits of these areas are discussed, as well as problems that may impede the achievement of the hoped-for developments. A significant number of the problems discussed are of a generic nature and could be of general interest to the industry. The final section of this document addresses the cost and time estimates for achieving the solutions to the problems discussed earlier. Emphasis is placed on the number, type, and cost of the human resources required for the project.

  3. Graphic Warning Labels and the Cost Savings from Reduced Smoking among Pregnant Women

    Directory of Open Access Journals (Sweden)

    John A. Tauras

    2017-02-01

    Full Text Available Introduction: The U.S. Food and Drug Administration (FDA has estimated the economic impact of Graphic Warning Labels (GWLs. By omitting the impact on tobacco consumption by pregnant women, the FDA analysis underestimates the economic benefits that would occur from the proposed regulations. There is a strong link between the occurrence of low birth weight babies and smoking while pregnant. Low birth weight babies in turn generate much higher hospital costs than normal birth weight babies. This study aims to fill the gap by quantifying the national hospital cost savings from the reductions in prenatal smoking that will arise if GWLs are implemented in the U.S. Data and Methods: This study uses several data sources. It uses Natality Data from the National Vital Statistics System of the National Center for Health Statistics (NCHS in 2013 to estimate the impact of prenatal smoking on the likelihood of having a low-birth-weight baby, controlling for socio-economic and demographic characteristics as well as medical and non-medical risk factors. Using these estimates, along with the estimates of Huang et al. (2014 regarding the effect of GWLs on smoking, we calculate the change in the number of LBW (low birth weight babies resulting from decreased prenatal smoking due to GWLs. Using this estimated change and the estimates from Russell et al. (2007 and AHRQ (2013 on the excess hospital costs of LBW babies, we calculate cost saving that arises from reduced prenatal smoking in response of GWLs. Results and Conclusions: Our results indicated that GWLs for this population could lead to hospital cost savings of 1.2 billion to 2.0 billion dollars over a 30 year horizon.

  4. Reducing Logistics Costs%降低企业物流成本

    Institute of Scientific and Technical Information of China (English)

    李振发

    2013-01-01

      The facts that China's logistics enterprises have high costs in terms of inventory and transportation, and lagging information technology are indisputable. The reason is that accounting is imperfect and logistics cost management falls short of comprehensive control means. In order to reduce the cost, the enterprises should plan logistics nodes scientifically, improving the level of rationalization;gain cost-effectiveness by means of a supply chain;speed up the logistics operation, improving the utilization efficiency of funds;constantly im-prove the quality of logistics services;build modern logistics networks and information systems;and enhance the ability of cost control.%  目前,我国物流企业费用高、库存成本及运输成本高,物流信息技术落后是不争的事实。其原因是会计核算不健全,物流成本管理缺乏综合控制手段。降低物流企业成本,应科学规划物流节点,提高物流合理化水平,采用供应链方式追求成本效益,加快物流运行速度,提高资金利用效率,不断提高物流服务质量,构建现代化物流网络和信息系统,增强物流企业成本控制能力。

  5. Effectiveness and cost of failure mode and effects analysis methodology to reduce neurosurgical site infections.

    Science.gov (United States)

    Hover, Alexander R; Sistrunk, William W; Cavagnol, Robert M; Scarrow, Alan; Finley, Phillip J; Kroencke, Audrey D; Walker, Judith L

    2014-01-01

    Mercy Hospital Springfield is a tertiary care facility with 32 000 discharges and 15 000 inpatient surgeries in 2011. From June 2009 through January 2011, a stable inpatient elective neurosurgery infection rate of 2.15% was observed. The failure mode and effects analysis (FMEA) methodology to reduce inpatient neurosurgery infections was utilized. Following FMEA implementation, overall elective neurosurgery infection rates were reduced to 1.51% and sustained through May 2012. Compared with baseline, the post-FMEA deep-space and organ infection rate was reduced by 41% (P = .052). Overall hospital inpatient clean surgery infection rates for the same time frame did not decrease to the same extent, suggesting a specific effect of the FMEA. The study team believes that the FMEA interventions resulted in 14 fewer expected infections, $270 270 in savings, a 168-day reduction in expected length of stay, and 22 fewer readmissions. Given the serious morbidity and cost of health care-associated infections, the study team concludes that FMEA implementation was clinically cost-effective.

  6. Reducing the cost of Ca-based direct air capture of CO2.

    Science.gov (United States)

    Zeman, Frank

    2014-10-07

    Direct air capture, the chemical removal of CO2 directly from the atmosphere, may play a role in mitigating future climate risk or form the basis of a sustainable transportation infrastructure. The current discussion is centered on the estimated cost of the technology and its link to "overshoot" trajectories, where atmospheric CO2 levels are actively reduced later in the century. The American Physical Society (APS) published a report, later updated, estimating the cost of a one million tonne CO2 per year air capture facility constructed today that highlights several fundamental concepts of chemical air capture. These fundamentals are viewed through the lens of a chemical process that cycles between removing CO2 from the air and releasing the absorbed CO2 in concentrated form. This work builds on the APS report to investigate the effect of modifications to the air capture system based on suggestions in the report and subsequent publications. The work shows that reduced carbon electricity and plastic packing materials (for the contactor) may have significant effects on the overall price, reducing the APS estimate from $610 to $309/tCO2 avoided. Such a reduction does not challenge postcombustion capture from point sources, estimated at $80/tCO2, but does make air capture a feasible alternative for the transportation sector and a potential negative emissions technology. Furthermore, air capture represents atmospheric reductions rather than simply avoided emissions.

  7. A decentralized approach to reducing the social costs of cascading failures

    Science.gov (United States)

    Hines, Paul

    Large cascading failures in electrical power networks come with enormous social costs. These can be direct financial costs, such as the loss of refrigerated foods in grocery stores, or more indirect social costs, such as the traffic congestion that results from the failure of traffic signals. While engineers and policy makers have made numerous technical and organizational changes to reduce the frequency and impact of large cascading failures, the existing data, as described in Chapter 2 of this work, indicate that the overall frequency and impact of large electrical blackouts in the United States are not decreasing. Motivated by the cascading failure problem, this thesis describes a new method for Distributed Model Predictive Control and a power systems application. The central goal of the method, when applied to power systems, is to reduce the social costs of cascading failures by making small, targeted reductions in load and generation and changes to generator voltage set points. Unlike some existing schemes that operate from centrally located control centers, the method is operated by software agents located at substations distributed throughout the power network. The resulting multi-agent control system is a new approach to decentralized control, combining Distributed Model Predictive Control and Reciprocal Altruism. Experimental results indicate that this scheme can in fact decrease the average size, and thus social costs, of cascading failures. Over 100 randomly generated disturbances to a model of the IEEE 300 bus test network, the method resulted in nearly an order of magnitude decrease in average event size (measured in cost) relative to cascading failure simulations without remedial control actions. Additionally, the communication requirements for the method are measured, and found to be within the bandwidth capabilities of current communications technology (on the order of 100kB/second). Experiments on several resistor networks with varying structures

  8. A way for reducing drug supply chain cost for a hospital district: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Postacchini, L.; Ciarapica, F.E.; Bevilacqua, M.; Mazzuto, G.; Paciarotti, C.

    2016-07-01

    This work aims at providing insights to optimise healthcare logistic of the drug management, in order to deal with the healthcare expenditure cut. In this paper the effects of different drug supply chain configurations, on the resulting average stock, service level and Bullwhip effect, of the studied supply chain, is quantitatively assessed. A case study of an Italian district has been studied, taking into account three echelons: suppliers, central stock, and hospitals. A model of the various supply chain configurations has been created with the use of the simulation. Specifically, 24 supply chain configurations have been examined, stemming from the combination of several supply chain design parameters, namely: transshipment policies (Emergency Lateral Transshipment or Total Inventory Equalization); re-order and inventory management policies (Economic Order Quantity or Economic Order Interval); required service levels (90% or 95%); the number of available vans (one or two). For each configuration, hospital average stock, service level and a “Bullwhip effect” analysis are computed. To know which input variables are statistically significant, a DoE (Design of Experiments) analysis has been executed. The output of this paper provides useful insights and suggestions to optimize the healthcare logistic and drug supply chain. According to the developed DoE analysis, it can be stated that the introduction of transshipment policies provides important improvement in terms of service and stock levels. To reduce the Bullwhip effect, which results in a service level decreasing, and in a managing stock costs increasing, it is worth to adopt an EOQ re-order policy. This research gives practical recommendations to the studied system, in order to reduce costs and maintain a very satisfactory service level. This paper fulfils an identified need to study which combination of transshipment policies, re-order/inventory management policies and required service levels, can be the

  9. Reducing the metabolic cost of walking with an ankle exoskeleton: interaction between actuation timing and power.

    Science.gov (United States)

    Galle, Samuel; Malcolm, Philippe; Collins, Steven Hartley; De Clercq, Dirk

    2017-04-27

    Powered ankle-foot exoskeletons can reduce the metabolic cost of human walking to below normal levels, but optimal assistance properties remain unclear. The purpose of this study was to test the effects of different assistance timing and power characteristics in an experiment with a tethered ankle-foot exoskeleton. Ten healthy female subjects walked on a treadmill with bilateral ankle-foot exoskeletons in 10 different assistance conditions. Artificial pneumatic muscles assisted plantarflexion during ankle push-off using one of four actuation onset timings (36, 42, 48 and 54% of the stride) and three power levels (average positive exoskeleton power over a stride, summed for both legs, of 0.2, 0.4 and 0.5 W∙kg(-1)). We compared metabolic rate, kinematics and electromyography (EMG) between conditions. Optimal assistance was achieved with an onset of 42% stride and average power of 0.4 W∙kg(-1), leading to 21% reduction in metabolic cost compared to walking with the exoskeleton deactivated and 12% reduction compared to normal walking without the exoskeleton. With suboptimal timing or power, the exoskeleton still reduced metabolic cost, but substantially less so. The relationship between timing, power and metabolic rate was well-characterized by a two-dimensional quadratic function. The assistive mechanisms leading to these improvements included reducing muscular activity in the ankle plantarflexors and assisting leg swing initiation. These results emphasize the importance of optimizing exoskeleton actuation properties when assisting or augmenting human locomotion. Our optimal assistance onset timing and average power levels could be used for other exoskeletons to improve assistance and resulting benefits.

  10. MANAGE THE ZONES OF UNCERTAINTIES TO REDUCE THE COST OF THE TRAINING IN THE ORGANIZATION

    Directory of Open Access Journals (Sweden)

    Bakhouche SEDDIK

    2017-06-01

    Full Text Available During the presentation of this study, we try to show a model that allows the upgrade of human resources and skills development in the workplace with a reduced cost. Through this proposal, we put emphasis on the actors and the areas of uncertainty in the organization, according to the theory of strategic analysis of Michel Crozier, on one part. Targeting, on the other part, the reliable transfer of knowledge, modern technologies and skills by the actors, as they have important influences on group members.

  11. Reducing costs of wind power with a gearless permanent-magnet generator

    Energy Technology Data Exchange (ETDEWEB)

    Vihriaelae, H.; Peraelae, R.; Soederlund, L.; Eriksson, J.T. [Tampere Univ. of Technology (Finland). Lab. of Electricity and Magnetism

    1995-12-31

    This article examines a disc-type axial-field permanent magnet generator (PMG) utilizing the latest generation of permanent magnet material, namely Nd{sub 15}B{sub 8}Fe{sub 77}. A frequency converter (FC) is needed to keep the system synchronized with the grid. It also offers a possibility to use variable speed. The main advantages of this novel system compared to the conventional one are a higher overall efficiency, better reliability, reduced weight and diminished need for maintenance, all contributing to the cost-reduction of wind power. (author)

  12. Building Commissioning: A Golden Opportunity for Reducing Energy Costs and Greenhouse-gas Emissions

    Energy Technology Data Exchange (ETDEWEB)

    Mills, Evan

    2009-07-16

    data are available revealed over 10,000 energy-related problems, resulting in 16% median whole-building energy savings in existing buildings and 13% in new construction, with payback time of 1.1 years and 4.2 years, respectively. In terms of other cost-benefit indicators, median benefit-cost ratios of 4.5 and 1.1, and cash-on-cash returns of 91% and 23% were attained for existing and new buildings, respectively. High-tech buildings were particularly cost-effective, and saved higher amounts of energy due to their energy-intensiveness. Projects with a comprehensive approach to commissioning attained nearly twice the overall median level of savings and five-times the savings of the least-thorough projects. It is noteworthy that virtually all existing building projects were cost-effective by each metric (0.4 years for the upper quartile and 2.4 years for the lower quartile), as were the majority of new-construction projects (1.5 years and 10.8 years, respectively). We also found high cost-effectiveness for each specific measure for which we have data. Contrary to a common perception, cost-effectiveness is often achieved even in smaller buildings. Thanks to energy savings valued more than the cost of the commissioning process, associated reductions in greenhouse gas emissions come at 'negative' cost. In fact, the median cost of conserved carbon is negative - -$110 per tonne for existing buildings and -$25/tonne for new construction - as compared with market prices for carbon trading and offsets in the +$10 to +$30/tonne range. Further enhancing the value of commissioning, its non-energy benefits surpass those of most other energy-management practices. Significant first-cost savings (e.g., through right-sizing of heating and cooling equipment) routinely offset at least a portion of commissioning costs - fully in some cases. When accounting for these benefits, the net median commissioning project cost was reduced by 49% on average, while in many cases they exceeded

  13. Stem transcriptome reveals mechanisms to reduce the energetic cost of shade-avoidance responses in tomato.

    Science.gov (United States)

    Cagnola, Juan Ignacio; Ploschuk, Edmundo; Benech-Arnold, Tomás; Finlayson, Scott A; Casal, Jorge José

    2012-10-01

    While the most conspicuous response to low red/far-red ratios (R:FR) of shade light perceived by phytochrome is the promotion of stem growth, additional, less obvious effects may be discovered by studying changes in the stem transcriptome. Here, we report rapid and reversible stem transcriptome responses to R:FR in tomato (Solanum lycopersicum). As expected, low R:FR promoted the expression of growth-related genes, including those involved in the metabolism of cell wall carbohydrates and in auxin responses. In addition, genes involved in flavonoid synthesis, isoprenoid metabolism, and photosynthesis (dark reactions) were overrepresented in clusters showing reduced expression in the stem of low R:FR-treated plants. Consistent with these responses, low R:FR decreased the levels of flavonoids (anthocyanin, quercetin, kaempferol) and selected isoprenoid derivatives (chlorophyll, carotenoids) in the stem and severely reduced the photosynthetic capacity of this organ. However, lignin contents were unaffected. Low R:FR reduced the stem levels of jasmonate, which is a known inducer of flavonoid synthesis. The rate of stem respiration was also reduced in low R:FR-treated plants, indicating that by downsizing the stem photosynthetic apparatus and the levels of photoprotective pigments under low R:FR, tomato plants reduce the energetic cost of shade-avoidance responses.

  14. Cost-utility analysis of interventions to reduce the burden of cervical cancer in Israel.

    Science.gov (United States)

    Ginsberg, Gary M

    2013-11-22

    Using World health Organization, CHOosing Interventions that are Cost Effective (WHO-CHOICE) methodology, cost-utility ratios were calculated for various interventions (Papanicolaou [Pap] smear, human papillomavirus [HPV]-DNA testing, visual inspection with acetic acid [VIA] and vaccination against HPV) at various frequencies to reduce the burden of cervical cancer and condyloma (in the case of the HPV vaccination) in Israel, which has a low prevalence of cervical cancer. All of the screening and/or vaccine interventions were very cost-effective. Attempts should be made to raise compliancy with Pap smears from the current opportunistic 12.1% per annum to screen everyone aged 20-64 once every 5 years in combination with HPV-DNA testing for persons aged 30-64 both before and/or after HPV vaccination is introduced. This article forms part of a regional report entitled "Comprehensive Control of HPV Infections and Related Diseases in Israel" Vaccine Volume 31, Supplement 8, 2013. Updates of the progress in the field are presented in a separate monograph entitled "Comprehensive Control of HPV Infections and Related Diseases" Vaccine Volume 30, Supplement 5, 2012. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Do female Nicrophorus vespilloides reduce direct costs by choosing males that mate less frequently?

    Science.gov (United States)

    Mazué, G. P. F.; Carter, M. J.; Head, M. L.; Moore, A. J.; Royle, N. J.

    2016-01-01

    Sexual conflict occurs when selection to maximize fitness in one sex does so at the expense of the other sex. In the burying beetle Nicrophorus vespilloides, repeated mating provides assurance of paternity at a direct cost to female reproductive productivity. To reduce this cost, females could choose males with low repeated mating rates or smaller, servile males. We tested this by offering females a dichotomous choice between males from lines selected for high or low mating rate. Each female was then allocated her preferred or non-preferred male to breed. Females showed no preference for males based on whether they came from lines selected for high or low mating rates. Pairs containing males from high mating rate lines copulated more often than those with low line males but there was a negative relationship between female size and number of times she mated with a non-preferred male. When females bred with their preferred male the number of offspring reared increased with female size but there was no such increase when breeding with non-preferred males. Females thus benefited from being choosy, but this was not directly attributable to avoidance of costly male repeated mating. PMID:26979560

  16. Phosphorus binding with ferric citrate is associated with fewer hospitalizations and reduced hospitalization costs.

    Science.gov (United States)

    Rodby, Roger; Umanath, Kausik; Niecestro, Robert; Jackson, James H; Sika, Mohammed; Lewis, Julia B; Dwyer, Jamie P

    2015-06-01

    Ferric citrate (FC) is a new phosphorus binder shown to increase serum iron stores while reducing intravenous iron and erythropoiesis-stimulating agent usage. Such reductions could lower hospitalization rates and associated costs. Hospitalizations during a Phase III trial were compared between FC and active control (AC). Hospitalization costs were estimated using the 2013 US Renal Data System Annual Data Report. 34.6% of FC patients were hospitalized at least once versus 45.6% of the AC group (risk reduction 24.2%; p = 0.02). There were 181 unique hospitalizations in the FC group versus 239 in the AC group, for a difference of 58 hospitalizations. Total potential savings was US$ 867,622 in hospitalization costs in the FC group. If the hospitalization reduction in our study was applied to the general end-stage renal disease population, this could translate into a savings of US$ 3002/patient/year. Patients receiving FC experienced fewer hospitalizations with the potential for significant savings.

  17. Pilot plant investigations on cleaning efficiencies to reduce hazelnut cross-contamination in industrial manufacture of cookies.

    Science.gov (United States)

    Röder, Martin; Ibach, Anja; Baltruweit, Iris; Gruyters, Helwig; Janise, Annabella; Suwelack, Carola; Matissek, Reinhard; Vieths, Stefan; Holzhauser, Thomas

    2008-11-01

    Shared equipment in industrial food manufacture has repeatedly been described as a potential source of unlabeled food allergens, i.e., hidden allergens. However, the impact of shared equipment on allergen cross-contamination is basically unknown. Therefore, we sought to investigate systematically the extent of hazelnut cross-contamination in fine bakery wares as a model. A product change from cookies with 10% hazelnut to cookies without hazelnuts was simulated on pilot plant equipment. The extent of hazelnut cross-contamination (HNCC) was analyzed by enzyme-linked immunosorbent assay (ELISA) for each production device (kneaders, rotary molder, wire cutting machine, and steel band oven) and various cleaning procedures used between products. The experiments were performed repeatedly with finely ground hazelnuts and with roughly chopped hazelnut kernels. Cross-contamination from chopped kernels was distributed statistically but not homogeneously, and sampling and analysis with the ELISA was therefore not reproducible. Further analysis concentrated on homogenously distributed HNCC from ground hazelnut. Apart from product changes without intermediate cleaning, the highest HNCC was found after mechanical scraping: Up to 100 mg/kg hazelnut protein was found in the follow-up product after processing by one machine. After additional cleaning with hot water, the HNCC decreased regardless of the processing device to levels at or below 1 mg/kg hazelnut protein. In our pilot plant study, the application of an appropriate wet cleaning procedure in combination with quantitative monitoring of the cleaning efficiency reduced the hazelnut protein cross-contamination to a level at which severe hazelnut-related allergic reactions are unlikely to occur.

  18. A comparison of response cost and differential reinforcement of other behavior to reduce disruptive behavior in a preschool classroom.

    OpenAIRE

    Conyers, Carole; Miltenberger, Raymond; Maki, Amber; Barenz, Rebecca; Jurgens, Mandy; Sailer, Angela; Haugen, Meredith; Kopp, Brandon

    2004-01-01

    This study investigated the effectiveness of response cost and differential reinforcement of other behavior (DRO) in reducing the disruptive behaviors of 25 children in a preschool classroom. Using an alternating treatments design, disruptive behavior was reduced when the participants earned tokens for the absence of disruptive behavior (DRO) or lost tokens for the occurrence of disruptive behavior (response cost). Initially, DRO was more successful in reducing the number of disruptive behavi...

  19. Reduced cost design of liquid lithium target for international fusion material irradiation facility (IFMIF)

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Hiroo; Ida, Mizuho; Sugimoto, Masayoshi; Takeuchi, Hiroshi [Department of Fussion Engineering Research, Naka Fusion Research Establishment, Japan Atomic Energy Research Institute, Tokai, Ibaraki (Japan); Yutani, Toshiaki [Toshiba Corp., Tokyo (Japan)

    2001-01-01

    The International Fusion Materials Irradiation Facility (IFMIF) is being jointly planned to provide an accelerator-based D-Li neutron source to produce intense high energy neutrons (2 MW/m{sup 2}) up to 200 dpa and a sufficient irradiation volume (500 cm{sup 3}) for testing the candidate materials and components up to about a full lifetime of their anticipated use in ITER and DEMO. To realize such a condition, 40 MeV deuteron beam with a current of 250 mA is injected into high speed liquid lithium flow with a speed of 20 m/s. Following Conceptual Design Activity (1995-1998), a design study with focus on cost reduction without changing its original mission has been done in 1999. The following major changes to the CAD target design have been considered in the study and included in the new design: i) number of the Li target has been changed from 2 to 1, ii) spare of impurity traps of the Li loop was removed although the spare will be stored in a laboratory for quick exchange, iii) building volume was reduced via design changes in lithium loop length. This paper describes the reduced cost design of the lithium target system and recent status of Key Element Technology activities. (author)

  20. Autonomous exoskeleton reduces metabolic cost of human walking during load carriage.

    Science.gov (United States)

    Mooney, Luke M; Rouse, Elliott J; Herr, Hugh M

    2014-05-09

    Many soldiers are expected to carry heavy loads over extended distances, often resulting in physical and mental fatigue. In this study, the design and testing of an autonomous leg exoskeleton is presented. The aim of the device is to reduce the energetic cost of loaded walking. In addition, we present the Augmentation Factor, a general framework of exoskeletal performance that unifies our results with the varying abilities of previously developed exoskeletons. We developed an autonomous battery powered exoskeleton that is capable of providing substantial levels of positive mechanical power to the ankle during the push-off region of stance phase. We measured the metabolic energy consumption of seven subjects walking on a level treadmill at 1.5 m/s, while wearing a 23 kg vest. During the push-off portion of the stance phase, the exoskeleton applied positive mechanical power with an average across the gait cycle equal to 23 ± 2 W (11.5 W per ankle). Use of the autonomous leg exoskeleton significantly reduced the metabolic cost of walking by 36 ± 12 W, which was an improvement of 8 ± 3% (p = 0.025) relative to the control condition of not wearing the exoskeleton. In the design of leg exoskeletons, the results of this study highlight the importance of minimizing exoskeletal power dissipation and added limb mass, while providing substantial positive power during the walking gait cycle.

  1. Effective information channels for reducing costs of environmentally- friendly technologies: evidence from residential PV markets

    Science.gov (United States)

    Rai, Varun; Robinson, Scott A.

    2013-03-01

    Realizing the environmental benefits of solar photovoltaics (PV) will require reducing costs associated with perception, informational gaps and technological uncertainties. To identify opportunities to decrease costs associated with residential PV adoption, in this letter we use multivariate regression models to analyze a unique, household-level dataset of PV adopters in Texas (USA) to systematically quantify the effect of different information channels on aspiring PV adopters’ decision-making. We find that the length of the decision period depends on the business model, such as whether the system was bought or leased, and on special opportunities to learn, such as the influence of other PV owners in the neighborhood. This influence accrues passively through merely witnessing PV systems in the neighborhood, increasing confidence and motivation, as well as actively through peer-to-peer communications. Using these insights we propose a new framework to provide public information on PV that could drastically reduce barriers to PV adoption, thereby accelerating its market penetration and environmental benefits. This framework could also serve as a model for other distributed generation technologies.

  2. Origin of how steam rockets can reduce space transport cost by orders of magnitude

    Science.gov (United States)

    Zuppero, Anthony; Larson, Thomas K.; Schnitzler, Bruce G.; Werner, James E.; Rice, John W.; Hill, Thomas J.; Richins, William D.; Parlier, Lynn

    1999-01-01

    A brief sketch shows the origin of why and how thermal rocket propulsion has the unique potential to dramatically reduce the cost of space transportation for most inner solar system missions of interest. Orders of magnitude reduction in cost are apparently possible when compared to all processes requiring electrolysis for the production of rocket fuels or propellants and to all electric propulsion systems. An order of magnitude advantage can be attributed to rocket propellant tank factors associated with storing water propellant, compared to cryogenic liquids. An order of magnitude can also be attributed to the simplicity of the extraction and processing of ice on the lunar surface, into an easily stored, non-cryogenic rocket propellant (water). A nuclear heated thermal rocket can deliver thousands of times its mass to Low Earth Orbit from the Lunar surface, providing the equivalent to orders of magnitude drop in launch cost for mass in Earth orbit. Mass includes water ice. These cost reductions depend (exponentially) on the mission delta-v requirements being less than about 6 km/s, or about 3 times the specific velocity of steam rockets (2 km/s, from Isp 200 sec). Such missions include: from the lunar surface to Low Lunar Orbit, (LLO), from LLO to lunar escape, from Low Earth Orbit (LEO) to Geosynchronous Orbit (GEO), from LEO to Earth Escape, from LEO to Mars Transfer Orbit, from LLO to GEO, missions returning payloads from about 10% of the periodic comets using propulsive capture to orbits around Earth itself, and fast, 100 day missions from Lunar Escape to Mars. All the assertions depend entirely and completely on the existence of abundant, nearly pure ice at the permanently dark North and South Poles of the Moon.

  3. Cost Effectiveness of a Novel Attempt to Reduce Readmission after Ileostomy Creation

    Science.gov (United States)

    Raza, Ahsan; Huang, Emina; Goldstein, Lindsey; Hughes, Steven J.; Tan, Sanda A.

    2017-01-01

    Background and Objectives: Dehydration is a common complication after ileostomy creation and is the most frequent reason for postoperative readmission to the hospital. We sought to determine the clinical and economic impact of an outpatient intervention to decrease readmissions for dehydration after ileostomy creation. Methods: All new ileostomates from 09/2011 through 10/2012 at the University of Florida were enrolled to receive an ileostomy education and management protocol and a daily telephone call for 3 weeks after discharge. Counseling and medication adjustments were provided, with a satisfaction survey at the end. Outcomes of these patients were compared to those in a historical control cohort. A cost analysis was conducted to calculate the savings to the hospital. Results: Thirty-eight patients were enrolled. All patients required telephone counseling, and the mean satisfaction score rating was 4.69, on a scale of 1 to 5. The readmission rate for dehydration within 30 days of discharge decreased significantly from 65% before intervention to 16% (5/32 patients) after intervention (P = .002). The length of readmission hospital stay decreased from a mean of 4.2 days before the introduction of the intervention to 3 days after. Cost analysis revealed that the actual total hospital cost of dehydration-specific readmission decreased from $88,858 to $25,037, a saving of $63,821. Conclusion: A standardized ileostomy pathway with comprehensive patient education and outpatient telephone follow-up is cost effective, has a positive influence on patient satisfaction, and reduces dehydration-related readmission rates. PMID:28144122

  4. Older adults learn less, but still reduce metabolic cost, during motor adaptation

    Science.gov (United States)

    Huang, Helen J.

    2013-01-01

    The ability to learn new movements and dynamics is important for maintaining independence with advancing age. Age-related sensorimotor changes and increased muscle coactivation likely alter the trial-and-error-based process of adapting to new movement demands (motor adaptation). Here, we asked, to what extent is motor adaptation to novel dynamics maintained in older adults (≥65 yr)? We hypothesized that older adults would adapt to the novel dynamics less well than young adults. Because older adults often use muscle coactivation, we expected older adults to use greater muscle coactivation during motor adaptation than young adults. Nevertheless, we predicted that older adults would reduce muscle activity and metabolic cost with motor adaptation, similar to young adults. Seated older (n = 11, 73.8 ± 5.6 yr) and young (n = 15, 23.8 ± 4.7 yr) adults made targeted reaching movements while grasping a robotic arm. We measured their metabolic rate continuously via expired gas analysis. A force field was used to add novel dynamics. Older adults had greater movement deviations and compensated for just 65% of the novel dynamics compared with 84% in young adults. As expected, older adults used greater muscle coactivation than young adults. Last, older adults reduced muscle activity with motor adaptation and had consistent reductions in metabolic cost later during motor adaptation, similar to young adults. These results suggest that despite increased muscle coactivation, older adults can adapt to the novel dynamics, albeit less accurately. These results also suggest that reductions in metabolic cost may be a fundamental feature of motor adaptation. PMID:24133222

  5. The costs of reducing loss to follow-up in South African cervical cancer screening

    Directory of Open Access Journals (Sweden)

    Kuhn Louise

    2005-11-01

    Full Text Available Abstract Background This study was designed to quantify the resources used in reestablishing contact with women who missed their scheduled cervical cancer screening visits and to assess the success of this effort in reducing loss to follow-up in a developing country setting. Methods Women were enrolled in this Cape Town, South Africa-based screening study between 2000 and 2003, and all had scheduled follow-up visits in 2003. Community health worker (CHW time, vehicle use, maintenance, and depreciation were estimated from weekly logs and cost accounting systems. The percentage of women who attended their scheduled visit, those who attended after CHW contact(s, and those who never returned despite attempted contact(s were determined. The number of CHW visits per woman was also estimated. Results 3,711 visits were scheduled in 2003. Of these, 2,321 (62.5% occurred without CHW contact, 918 (24.8% occurred after contact(s, and 472 (12.7% did not occur despite contact(s. Loss to follow-up was reduced from 21% to 6%, 39% to 10%, and 50% to 24% for 6, 12, and 24-month visits. CHWs attempted 3,200 contacts in 530 trips. On average, 3 CHWs attempted to contact 6 participants over each 111 minute trip. The per-person cost (2003 Rand for these activities was 12.75, 24.92, and 40.50 for 6, 12, and 24-month visits. Conclusion CHW contact with women who missed scheduled visits increased their return rate. Cost-effectiveness analyses aimed at policy decisions about cervical cancer screening in developing countries should incorporate these findings.

  6. Low cost back contact heterojunction solar cells on thin c-Si wafers. integrating laser and thin film processing for improved manufacturability

    Energy Technology Data Exchange (ETDEWEB)

    Hegedus, Steven S. [Univ. of Delaware, Newark, DE (United States)

    2015-09-08

    An interdigitated back contact (IBC) Si wafer solar cell with deposited a-Si heterojunction (HJ) emitter and contacts is considered the ultimate single junction Si solar cell design. This was confirmed in 2014 by both Panasonic and Sharp Solar producing IBC-HJ cells breaking the previous record Si solar cell efficiency of 25%. But manufacturability at low cost is a concern for the complex IBC-HJ device structure. In this research program, our goals were to addressed the broad industry need for a high-efficiency c-Si cell that overcomes the dominant module cost barriers by 1) developing thin Si wafers synthesized by innovative, kerfless techniques; 2) integrating laser-based processing into most aspects of solar cell fabrication, ensuring high speed and low thermal budgets ; 3) developing an all back contact cell structure compatible with thin wafers using a simplified, low-temperature fabrication process; and 4) designing the contact patterning to enable simplified module assembly. There were a number of significant achievements from this 3 year program. Regarding the front surface, we developed and applied new method to characterize critical interface recombination parameters including interface defect density Dit and hole and electron capture cross-section for use as input for 2D simulation of the IBC cell to guide design and loss analysis. We optimized the antireflection and passivation properties of the front surface texture and a-Si/a-SiN/a-SiC stack depositions to obtain a very low (< 6 mA/cm2) front surface optical losses (reflection and absorption) while maintaining excellent surface passivation (SRV<5 cm/s). We worked with kerfless wafer manufacturers to apply defect-engineering techniques to improve bulk minority-carrier lifetime of thin kerfless wafers by both reducing initial impurities during growth and developing post-growth gettering techniques. This led insights about the kinetics of nickel, chromium, and dislocations in PV-grade silicon and to

  7. Low cost back contact heterojunction solar cells on thin c-Si wafers. Integrating laser and thin film processing for improved manufacturability

    Energy Technology Data Exchange (ETDEWEB)

    Hegedus, Steven S. [Univ. of Delaware, Newark, DE (United States)

    2015-09-08

    An interdigitated back contact (IBC) Si wafer solar cell with deposited a-Si heterojunction (HJ) emitter and contacts is considered the ultimate single junction Si solar cell design. This was confirmed in 2014 by both Panasonic and Sharp Solar producing IBC-HJ cells breaking the previous record Si solar cell efficiency of 25%. But manufacturability at low cost is a concern for the complex IBC-HJ device structure. In this research program, our goals were to addressed the broad industry need for a high-efficiency c-Si cell that overcomes the dominant module cost barriers by 1) developing thin Si wafers synthesized by innovative, kerfless techniques; 2) integrating laser-based processing into most aspects of solar cell fabrication, ensuring high speed and low thermal budgets ; 3) developing an all back contact cell structure compatible with thin wafers using a simplified, low-temperature fabrication process; and 4) designing the contact patterning to enable simplified module assembly. There were a number of significant achievements from this 3 year program. Regarding the front surface, we developed and applied new method to characterize critical interface recombination parameters including interface defect density Dit and hole and electron capture cross-section for use as input for 2D simulation of the IBC cell to guide design and loss analysis. We optimized the antireflection and passivation properties of the front surface texture and a-Si/a-SiN/a-SiC stack depositions to obtain a very low (< 6 mA/cm2) front surface optical losses (reflection and absorption) while maintaining excellent surface passivation (SRV<5 cm/s). We worked with kerfless wafer manufacturers to apply defect-engineering techniques to improve bulk minority-carrier lifetime of thin kerfless wafers by both reducing initial impurities during growth and developing post-growth gettering techniques. This led insights about the kinetics of nickel, chromium, and dislocations in PV-grade silicon and to

  8. Use of Biostratigraphy to Increase Production, Reduce Operating Costs and Risks and Reduce Environmental Concerns in Oil Well Drilling

    Energy Technology Data Exchange (ETDEWEB)

    Edward Marks

    2005-09-09

    out at the top of the late Miocene, early Mohnian: Bolivina aff hughesi, Rotalia becki, Suggrunda californica, Virgulina grandis, Virgulina ticensis, Bulimina ecuadorana, Denticula lauta and Nonion medio-costatum. Please see Appendix B, Fig. 1, Neogene Zones, p. 91 and Appendix C, chart 5, p. 99 By the use of Stratigraphy, employing both Paleontology and Lithology, we can increase hydrocarbon production, reduce operating costs and risks by the identification of the productive sections, and reduce environmental concerns by drilling less dry holes needlessly.

  9. Methodology and Technology for Design to Cost

    Institute of Scientific and Technical Information of China (English)

    姜华; 曾庆良; 熊光楞

    2001-01-01

    Product cost is one of the most important factors affectingproduct market share. Traditionally, product costs are estimated after they are manufactured. However, in this way, the best opportunity to control product cost is lost. In this paper, a method trying to reduce product cost at the design stage is proposed. This method is called Design to Cost (DTC). According to this method, product structure can be optimized with the application of value engineering and Design for Manufacturing/Assembly (DFMA) criteria in the conceptual stage of product design. During embodiment design, products are evaluated economically on the basis of the product model which includes manufacturing, assembly and test cost information. According to the results, products are redesigned before manufacture, and the production cost is reduced.

  10. A conceptual framework for the evaluation of cost-effectiveness of projects to reduce GHG emissions and sequester carbon

    Energy Technology Data Exchange (ETDEWEB)

    Sathaye, J.; Norgaard, R.; Makundi, W.

    1993-07-01

    This paper proposes a conceptual framework for evaluating the cost of projects to reduce atmospheric greenhouse gases (GHGs). The evaluation of cost-effectiveness should account for both the timing of carbon emissions and the damage caused by the atmospheric stock of carbon. We develop a conceptual basis to estimate the cost-effectiveness of projects in terms of the cost of reducing atmospheric carbon (CRAC) and other GHGs. CRAC accounts for the economic discount rate, alternative functional forms of the shadow price, the residence period of carbon in the atmosphere, and the multiple monetary benefits of projects. The last item is of particular importance to the developing countries.

  11. A cost effectiveness analysis of salt reduction policies to reduce coronary heart disease in four Eastern Mediterranean countries.

    Directory of Open Access Journals (Sweden)

    Helen Mason

    Full Text Available BACKGROUND: Coronary Heart Disease (CHD is rising in middle income countries. Population based strategies to reduce specific CHD risk factors have an important role to play in reducing overall CHD mortality. Reducing dietary salt consumption is a potentially cost-effective way to reduce CHD events. This paper presents an economic evaluation of population based salt reduction policies in Tunisia, Syria, Palestine and Turkey. METHODS AND FINDINGS: Three policies to reduce dietary salt intake were evaluated: a health promotion campaign, labelling of food packaging and mandatory reformulation of salt content in processed food. These were evaluated separately and in combination. Estimates of the effectiveness of salt reduction on blood pressure were based on a literature review. The reduction in mortality was estimated using the IMPACT CHD model specific to that country. Cumulative population health effects were quantified as life years gained (LYG over a 10 year time frame. The costs of each policy were estimated using evidence from comparable policies and expert opinion including public sector costs and costs to the food industry. Health care costs associated with CHDs were estimated using standardized unit costs. The total cost of implementing each policy was compared against the current baseline (no policy. All costs were calculated using 2010 PPP exchange rates. In all four countries most policies were cost saving compared with the baseline. The combination of all three policies (reducing salt consumption by 30% resulted in estimated cost savings of $235,000,000 and 6455 LYG in Tunisia; $39,000,000 and 31674 LYG in Syria; $6,000,000 and 2682 LYG in Palestine and $1,3000,000,000 and 378439 LYG in Turkey. CONCLUSION: Decreasing dietary salt intake will reduce coronary heart disease deaths in the four countries. A comprehensive strategy of health education and food industry actions to label and reduce salt content would save both money and lives.

  12. A cost effectiveness analysis of salt reduction policies to reduce coronary heart disease in four Eastern Mediterranean countries.

    Science.gov (United States)

    Mason, Helen; Shoaibi, Azza; Ghandour, Rula; O'Flaherty, Martin; Capewell, Simon; Khatib, Rana; Jabr, Samer; Unal, Belgin; Sözmen, Kaan; Arfa, Chokri; Aissi, Wafa; Ben Romdhane, Habiba; Fouad, Fouad; Al-Ali, Radwan; Husseini, Abdullatif

    2014-01-01

    Coronary Heart Disease (CHD) is rising in middle income countries. Population based strategies to reduce specific CHD risk factors have an important role to play in reducing overall CHD mortality. Reducing dietary salt consumption is a potentially cost-effective way to reduce CHD events. This paper presents an economic evaluation of population based salt reduction policies in Tunisia, Syria, Palestine and Turkey. Three policies to reduce dietary salt intake were evaluated: a health promotion campaign, labelling of food packaging and mandatory reformulation of salt content in processed food. These were evaluated separately and in combination. Estimates of the effectiveness of salt reduction on blood pressure were based on a literature review. The reduction in mortality was estimated using the IMPACT CHD model specific to that country. Cumulative population health effects were quantified as life years gained (LYG) over a 10 year time frame. The costs of each policy were estimated using evidence from comparable policies and expert opinion including public sector costs and costs to the food industry. Health care costs associated with CHDs were estimated using standardized unit costs. The total cost of implementing each policy was compared against the current baseline (no policy). All costs were calculated using 2010 PPP exchange rates. In all four countries most policies were cost saving compared with the baseline. The combination of all three policies (reducing salt consumption by 30%) resulted in estimated cost savings of $235,000,000 and 6455 LYG in Tunisia; $39,000,000 and 31674 LYG in Syria; $6,000,000 and 2682 LYG in Palestine and $1,3000,000,000 and 378439 LYG in Turkey. Decreasing dietary salt intake will reduce coronary heart disease deaths in the four countries. A comprehensive strategy of health education and food industry actions to label and reduce salt content would save both money and lives.

  13. Alternative Strategies to Reduce Maternal Mortality in India: A Cost-Effectiveness Analysis

    Science.gov (United States)

    Goldie, Sue J.; Sweet, Steve; Carvalho, Natalie; Natchu, Uma Chandra Mouli; Hu, Delphine

    2010-01-01

    Background Approximately one-quarter of all pregnancy- and delivery-related maternal deaths worldwide occur in India. Taking into account the costs, feasibility, and operational complexity of alternative interventions, we estimate the clinical and population-level benefits associated with strategies to improve the safety of pregnancy and childbirth in India. Methods and Findings Country- and region-specific data were synthesized using a computer-based model that simulates the natural history of pregnancy (both planned and unintended) and pregnancy- and childbirth-associated complications in individual women; and considers delivery location, attendant, and facility level. Model outcomes included clinical events, population measures, costs, and cost-effectiveness ratios. Separate models were adapted to urban and rural India using survey-based data (e.g., unmet need for birth spacing/limiting, facility births, skilled birth attendants). Model validation compared projected maternal indicators with empiric data. Strategies consisted of improving coverage of effective interventions that could be provided individually or packaged as integrated services, could reduce the incidence of a complication or its case fatality rate, and could include improved logistics such as reliable transport to an appropriate referral facility as well as recognition of referral need and quality of care. Increasing family planning was the most effective individual intervention to reduce pregnancy-related mortality. If over the next 5 y the unmet need for spacing and limiting births was met, more than 150,000 maternal deaths would be prevented; more than US$1 billion saved; and at least one of every two abortion-related deaths averted. Still, reductions in maternal mortality reached a threshold (∼23%–35%) without including strategies that ensured reliable access to intrapartum and emergency obstetrical care (EmOC). An integrated and stepwise approach was identified that would ultimately

  14. Alternative strategies to reduce maternal mortality in India: a cost-effectiveness analysis.

    Science.gov (United States)

    Goldie, Sue J; Sweet, Steve; Carvalho, Natalie; Natchu, Uma Chandra Mouli; Hu, Delphine

    2010-04-20

    Approximately one-quarter of all pregnancy- and delivery-related maternal deaths worldwide occur in India. Taking into account the costs, feasibility, and operational complexity of alternative interventions, we estimate the clinical and population-level benefits associated with strategies to improve the safety of pregnancy and childbirth in India. Country- and region-specific data were synthesized using a computer-based model that simulates the natural history of pregnancy (both planned and unintended) and pregnancy- and childbirth-associated complications in individual women; and considers delivery location, attendant, and facility level. Model outcomes included clinical events, population measures, costs, and cost-effectiveness ratios. Separate models were adapted to urban and rural India using survey-based data (e.g., unmet need for birth spacing/limiting, facility births, skilled birth attendants). Model validation compared projected maternal indicators with empiric data. Strategies consisted of improving coverage of effective interventions that could be provided individually or packaged as integrated services, could reduce the incidence of a complication or its case fatality rate, and could include improved logistics such as reliable transport to an appropriate referral facility as well as recognition of referral need and quality of care. Increasing family planning was the most effective individual intervention to reduce pregnancy-related mortality. If over the next 5 y the unmet need for spacing and limiting births was met, more than 150,000 maternal deaths would be prevented; more than US$1 billion saved; and at least one of every two abortion-related deaths averted. Still, reductions in maternal mortality reached a threshold ( approximately 23%-35%) without including strategies that ensured reliable access to intrapartum and emergency obstetrical care (EmOC). An integrated and stepwise approach was identified that would ultimately prevent four of five

  15. Interest of a prescreening questionnaire to reduce the cost of bone densitometry.

    Science.gov (United States)

    Ben Sedrine, W; Broers, P; Devogelaer, J P; Depresseux, G; Kaufman, J M; Goemaere, S; Reginster, J Y

    2002-05-01

    subjects who would be recommended for a densitometry test, only a small fraction were identified correctly (the positive predictive values varied from 11.3% at the total hip to 34.8% at any site). In this first setting, the suggested criteria seem useful chiefly for excluding subjects who do not need a DXA scan rather than selecting osteoporotic patients. When applied only to patients aged 61 years or more, the positive predictive values rose to 15.1% (total hip) and 42.9% (any site), whereas the corresponding negative predictive values were set at 93% and 68.6%. In comparison, with a mass screening scenario the estimated diagnostic costs (costs associated with the DXA procedure) per osteoporotic patient detected at any of the considered sites would be reduced by more than 9% (59.4 instead of 65.3 Euros) if the suggested indications are taken into account for prescreening patients. And when the questionnaire is applied only to women over the age of 60 years these costs would be further reduced to 50.6 Euros, representing a 23% decrease. Then, a prescreening strategy based on these indications concomitantly with an age-selective criterion could represent a promising way toward a more rational use of BMD measurement.

  16. Alternative strategies to reduce maternal mortality in India: a cost-effectiveness analysis.

    Directory of Open Access Journals (Sweden)

    Sue J Goldie

    2010-04-01

    Full Text Available BACKGROUND: Approximately one-quarter of all pregnancy- and delivery-related maternal deaths worldwide occur in India. Taking into account the costs, feasibility, and operational complexity of alternative interventions, we estimate the clinical and population-level benefits associated with strategies to improve the safety of pregnancy and childbirth in India. METHODS AND FINDINGS: Country- and region-specific data were synthesized using a computer-based model that simulates the natural history of pregnancy (both planned and unintended and pregnancy- and childbirth-associated complications in individual women; and considers delivery location, attendant, and facility level. Model outcomes included clinical events, population measures, costs, and cost-effectiveness ratios. Separate models were adapted to urban and rural India using survey-based data (e.g., unmet need for birth spacing/limiting, facility births, skilled birth attendants. Model validation compared projected maternal indicators with empiric data. Strategies consisted of improving coverage of effective interventions that could be provided individually or packaged as integrated services, could reduce the incidence of a complication or its case fatality rate, and could include improved logistics such as reliable transport to an appropriate referral facility as well as recognition of referral need and quality of care. Increasing family planning was the most effective individual intervention to reduce pregnancy-related mortality. If over the next 5 y the unmet need for spacing and limiting births was met, more than 150,000 maternal deaths would be prevented; more than US$1 billion saved; and at least one of every two abortion-related deaths averted. Still, reductions in maternal mortality reached a threshold ( approximately 23%-35% without including strategies that ensured reliable access to intrapartum and emergency obstetrical care (EmOC. An integrated and stepwise approach was

  17. Use of operating room information system data to predict the impact of reducing turnover times on staffing costs.

    Science.gov (United States)

    Dexter, Franklin; Abouleish, Amr E; Epstein, Richard H; Whitten, Charles W; Lubarsky, David A

    2003-10-01

    Potential benefits to reducing turnover times are both quantitative (e.g., complete more cases and reduce staffing costs) and qualitative (e.g., improve professional satisfaction). Analyses have shown the quantitative arguments to be unsound except for reducing staffing costs. We describe a methodology by which each surgical suite can use its own numbers to calculate its individual potential reduction in staffing costs from reducing its turnover times. Calculations estimate optimal allocated operating room (OR) time (based on maximizing OR efficiency) before and after reducing the maximum and average turnover times. At four academic tertiary hospitals, reductions in average turnover times of 3 to 9 min would result in 0.8% to 1.8% reductions in staffing cost. Reductions in average turnover times of 10 to 19 min would result in 2.5% to 4.0% reductions in staffing costs. These reductions in staffing cost are achieved predominantly by reducing allocated OR time, not by reducing the hours that staff work late. Heads of anesthesiology groups often serve on OR committees that are fixated on turnover times. Rather than having to argue based on scientific studies, this methodology provides the ability to show the specific quantitative effects (small decreases in staffing costs and allocated OR time) of reducing turnover time using a surgical suite's own data. Many anesthesiologists work at hospitals where surgeons and/or operating room (OR) committees focus repeatedly on turnover time reduction. We developed a methodology by which the reductions in staffing cost as a result of turnover time reduction can be calculated for each facility using its own data. Staffing cost reductions are generally very small and would be achieved predominantly by reducing allocated OR time to the surgeons.

  18. Trade in the US and Mexico helps reduce environmental costs of agriculture

    Science.gov (United States)

    Martinez-Melendez, Luz A.; Bennett, Elena M.

    2016-05-01

    Increasing international crop trade has enlarged global shares of cropland, water and fertilizers used to grow crops for export. Crop trade can reduce the environmental burden on importing countries, which benefit from embedded environmental resources in imported crops, and from avoided environmental impacts of production in their territory. International trade can also reduce the universal environmental impact of food production if crops are grown where they are produced in the most environmentally efficient way. We compared production efficiencies for the same crops in the US and Mexico to determine whether current crop trade between these two countries provides an overall benefit to the environment. Our economic and environmental accounting for the key traded crops from 2010 to 2014 shows that exports to Mexico are just 3% (∼16 thousand Gg) of the total production of these crops in the US, and exports to US represent roughly 0.13% (∼46 Gg) of Mexican total production of the same crops. Yields were higher in US than Mexico for all crops except wheat. Use of nitrogen fertilizer was higher in US than in Mexico for all crops except corn. Current trade reduces some, but not all, environmental costs of agriculture. A counterfactual trade scenario showed that an overall annual reduction in cultivated land (∼371 thousand ha), water use (∼923 million m3), fertilizer use (∼122 Gg; ∼68 Gg nitrogen) and pollution (∼681 tonnes of N2O emissions to the atmosphere and ∼511 tonnes of leached nitrogen) can be achieved by changing the composition of food products traded. In this case, corn, soybeans and rice should be grown in the US, while wheat, sorghum and barley should be grown in Mexico. Assigning greater economic weight to the environmental costs of agriculture might improve the balance of trade to be more universally beneficial, environmentally.

  19. Cost of production. Maximize profitability in the manufacture of solar modules; Maximizar la rentabilidad en la fabricacion de modulos solares

    Energy Technology Data Exchange (ETDEWEB)

    King, G. R.

    2011-07-01

    Plus the cost of photovoltaic energy production, parity with the network also consider the total investment made to generate a certain amount of energy. Some factors to consider include production, labor, initial cost of system components, installation, operation and maintenance. (Author)

  20. Manufacture of ammonium sulfate fertilizer from gypsum-rich byproduct of flue gas desulfurization - A prefeasibility cost estimate

    Science.gov (United States)

    Chou, I.-Ming; Rostam-Abadi, M.; Lytle, J.M.; Achorn, F.P.

    1996-01-01

    Costs for constructing and operating a conceptual plant based on a proposed process that converts flue gas desulfurization (FGD)-gypsum to ammonium sulfate fertilizer has been calculated and used to estimate a market price for the product. The average market price of granular ammonium sulfate ($138/ton) exceeds the rough estimated cost of ammonium sulfate from the proposed process ($111/ ton), by 25 percent, if granular size ammonium sulfate crystals of 1.2 to 3.3 millimeters in diameters can be produced by the proposed process. However, there was at least ??30% margin in the cost estimate calculations. The additional costs for compaction, if needed to create granules of the required size, would make the process uneconomical unless considerable efficiency gains are achieved to balance the additional costs. This study suggests the need both to refine the crystallization process and to find potential markets for the calcium carbonate produced by the process.

  1. Designing using manufacturing features

    Science.gov (United States)

    Szecsi, T.; Hoque, A. S. M.

    2012-04-01

    This paper presents a design system that enables the composition of a part using manufacturing features. Features are selected from feature libraries. Upon insertion, the system ensures that the feature does not contradict the design-for-manufacture rules. This helps eliminating costly manufacturing problems. The system is developed as an extension to a commercial CAD/CAM system Pro/Engineer.

  2. The impact of unit cost reductions on gross profit: Increasing or decreasing returns?

    Directory of Open Access Journals (Sweden)

    Ely Dahan

    2011-09-01

    Full Text Available We suggest that marketers actively participate in reducing unit costs during new product development, consistent with the theme of integrated marketing and manufacturing. Most marketing managers misjudge the impact on gross profit of reducing variable unit manufacturing costs, mistakenly believing that such cost reductions yield decreasing or linear returns while they actually generate increasing returns.

  3. The Role of Patient Financial Assistance Programs in Reducing Costs for Cancer Patients.

    Science.gov (United States)

    Zullig, Leah L; Wolf, Steven; Vlastelica, Lisa; Shankaran, Veena; Zafar, S Yousuf

    2017-04-01

    Limited transparency exists regarding eligibility and benefits for patient financial assistance programs (PAPs). To describe oral anticancer medication costs, insurance coverage, and the degree of financial assistance provided by PAPs. This was a retrospective study of prescription anticancer medication costs and PAP coverage. The study used data from an academic cancer center's specialty pharmacy. Medication, cost, and coverage data were collected from the specialty pharmacy database for prescriptions filled from January 2013 to November 2015. Prescriptions with missing copayments, insurance, or financial assistance amounts were excluded. Descriptive statistics summarized prescription characteristics. Of 9,388 anticancer medication prescriptions filled, 8,212 (87%) had complete cost data and were included. The 5 most common medications prescribed were capecitabine (20%), temozolomide (13%), enzalutamide (10%), letrozole (6%), and tamoxifen (4%). Most prescriptions were covered by commercial insurance or Part D (41.6%, n = 3,418). The median copayment was $20 per prescription (interquartile range [IQR] = $10.00-$80.30). When considering all prescriptions that received PAP assistance, the median amount of financial assistance provided by PAPs per prescription was $411.0 (IQR = $302.80-$523.40), amounting to 15% of the median prescription cash price. When considering all prescriptions, the median amount of financial assistance provided by PAPs per prescription was $0, and the mean was $79.30 (SD = $389.90). A minority of prescriptions received financial assistance from PAPs. The proportion of financial assistance was small relative to the price billed to insurance. PAPs play a modest role in reducing anticancer prescription-related costs. Support of this project by The Duke Biostatistics Core was made possible by Grant Number UL1TR001117 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health (NIH), and

  4. An Investigation into the Comparative Costs of Additive Manufacture vs. Machine from Solid for Aero Engine Parts

    Science.gov (United States)

    2006-05-01

    Shape Processing (Rentabilite de fabrication par un traitement de finition immediate), The original document contains color images. 14. ABSTRACT 15...removal of surface finish effects and to allow for slight thermal distortion effects on cooling. 1.2.2 Additive Manufacturing Process The method of...its forming temperature. A machining allowance is also provided to allow surface effects such as skin stresses and oxidation caused by the forging

  5. A way for reducing drug supply chain cost for a hospital district: A case study

    Directory of Open Access Journals (Sweden)

    Leonardo Postacchini

    2016-03-01

    Full Text Available Purpose: This work aims at providing insights to optimise healthcare logistic of the drug management, in order to deal with the healthcare expenditure cut. In this paper the effects of different drug supply chain configurations, on the resulting average stock, service level and Bullwhip effect, of the studied supply chain, is quantitatively assessed. Design/methodology/approach: A case study of an Italian district has been studied, taking into account three echelons: suppliers, central stock, and hospitals. A model of the various supply chain configurations has been created with the use of the simulation. Specifically, 24 supply chain configurations have been examined, stemming from the combination of several supply chain design parameters, namely: transshipment policies (Emergency Lateral Transshipment or Total Inventory Equalization; re-order and inventory management policies (Economic Order Quantity or Economic Order Interval; required service levels (90% or 95%; the number of available vans (one or two. For each configuration, hospital average stock, service level and a “Bullwhip effect” analysis are computed. To know which input variables are statistically significant, a DoE (Design of Experiments analysis has been executed. Findings: The output of this paper provides useful insights and suggestions to optimize the healthcare logistic and drug supply chain. According to the developed DoE analysis, it can be stated that the introduction of transshipment policies provides important improvement in terms of service and stock levels. To reduce the Bullwhip effect, which results in a service level decreasing, and in a managing stock costs increasing, it is worth to adopt an EOQ re-order policy. Practical implications: This research gives practical recommendations to the studied system, in order to reduce costs and maintain a very satisfactory service level. Originality/value: This paper fulfils an identified need to study which combination of

  6. Innovative Manufacturing of Launch Vehicle Structures - Integrally Stiffened Cylinder Process

    Science.gov (United States)

    Wagner, John; Domack, Marcia; Tayon, Wesley; Bird, Richard K.

    2017-01-01

    Reducing launch costs is essential to ensuring the success of NASA's visions for planetary exploration and earth science, economical support of the International Space Station, and competitiveness of the U.S. commercial launch industry. Reducing launch vehicle manufacturing cost supports NASA's budget and technology development priorities.

  7. Manufacturing technology

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, J.A.; Floyd, H.L.; Goetsch, B.; Doran, L. [eds.

    1993-08-01

    This bulletin depicts current research on manufacturing technology at Sandia laboratories. An automated, adaptive process removes grit overspray from jet engine turbine blades. Advanced electronic ceramics are chemically prepared from solution for use in high- voltage varistors. Selective laser sintering automates wax casting pattern fabrication. Numerical modeling improves performance of photoresist stripper (simulation on Cray supercomputer reveals path to uniform plasma). And mathematical models help make dream of low- cost ceramic composites come true.

  8. Reducing Cost of Rabies Post Exposure Prophylaxis: Experience of a Tertiary Care Hospital in Pakistan.

    Directory of Open Access Journals (Sweden)

    Naseem Salahuddin

    2016-02-01

    Full Text Available Rabies is a uniformly fatal disease, but preventable by timely and correct use of post exposure prophylaxis (PEP. Unfortunately, many health care facilities in Pakistan do not carry modern life-saving vaccines and rabies immunoglobulin (RIG, assuming them to be prohibitively expensive and unsafe. Consequently, Emergency Department (ED health care professionals remain untrained in its application and refer patients out to other hospitals. The conventional Essen regimen requires five vials of cell culture vaccine (CCV per patient, whereas Thai Red Cross intradermal (TRC-id regimen requires only one vial per patient, and gives equal seroconversion as compared with Essen regimen.This study documents the cost savings in using the Thai Red Cross intradermal regimen with cell culture vaccine instead of the customary 5-dose Essen intramuscular regimen for eligible bite victims. All patients presenting to the Indus Hospital ED between July 2013 to June 2014 with animal bites received WHO recommended PEP. WHO Category 2 bites received intradermal vaccine alone, while Category 3 victims received vaccine plus wound infiltration with Equine RIG. Patients were counseled, and subsequent doses of the vaccine administered on days 3, 7 and 28. Throughput of cases, consumption utilization of vaccine and ERIG and the cost per patient were recorded.Government hospitals in Pakistan are generally underfinanced and cannot afford treatment of the enormous burden of dog bite victims. Hence, patients are either not treated at all, or asked to purchase their own vaccine, which most cannot afford, resulting in neglect and high incidence of rabies deaths. TRC-id regimen reduced the cost of vaccine to 1/5th of Essen regimen and is strongly recommended for institutions with large throughput. Training ED staff would save lives through a safe, effective and affordable technique.

  9. Feasibility studies to improve plant availability and reduce total installed cost in IGCC plants

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, Kevin [General Electric Company, Houston, TX (United States); Anasti, William [General Electric Company, Houston, TX (United States); Fang, Yichuan [General Electric Company, Houston, TX (United States); Subramanyan, Karthik [General Electric Company, Houston, TX (United States); Leininger, Tom [General Electric Company, Houston, TX (United States); Zemsky, Christine [General Electric Company, Houston, TX (United States)

    2015-03-30

    The main purpose of this project is to look at technologies and philosophies that would help reduce the costs of an Integrated Gasification Combined Cycle (IGCC) plant, increase its availability or do both. GE’s approach to this problem is to consider options in three different areas: 1) technology evaluations and development; 2) constructability approaches; and 3) design and operation methodologies. Five separate tasks were identified that fall under the three areas: Task 2 – Integrated Operations Philosophy; Task 3 – Slip Forming of IGCC Components; Task 4 – Modularization of IGCC Components; Task 5 – Fouling Removal; and Task 6 – Improved Slag Handling. Overall, this project produced results on many fronts. Some of the ideas could be utilized immediately by those seeking to build an IGCC plant in the near future. These include the considerations from the Integrated Operations Philosophy task and the different construction techniques of Slip Forming and Modularization (especially if the proposed site is in a remote location or has a lack of a skilled workforce). Other results include ideas for promising technologies that require further development and testing to realize their full potential and be available for commercial operation. In both areas GE considers this project to be a success in identifying areas outside the core IGCC plant systems that are ripe for cost reduction and ity improvement opportunities.

  10. Complementarity in the provision of ecosystem services reduces the cost of mitigating amplified natural disturbance events.

    Science.gov (United States)

    Sims, Charles; Aadland, David; Powell, James; Finnoff, David C; Crabb, Ben

    2014-11-25

    Climate change has been implicated as a root cause of the recent surge in natural disturbance events such as storms, wildfires, and insect outbreaks. This climate-based surge has led to a greater focus on disturbance-mitigating benefits of ecosystem management. Quantifying these benefits requires knowledge of the relationship between natural and anthropogenic disturbances, which is lacking at the temporal and spatial scales needed to inform ecosystem-based management. This study investigates a specific relationship between timber harvesting and climate-amplified outbreaks of mountain pine beetle. If harvesting is located to mitigate long-distance insect dispersal, there is potential for a win-win outcome in which both timber production and forest conservation can be increased. This spatially targeted harvesting strategy lowers the cost of providing disturbance-mitigating ecosystem services, because valuable timber products are also produced. Mitigating long-distance dispersal also produces net gains in forest conservation across various stakeholder groups. These results speak to ongoing federal efforts to encourage forest vegetation removal on public forestlands to improve forest health. These efforts will lower the cost of responding to climate-amplified natural disturbance events but only if vegetation removal efforts are spatially located to reduce disturbance risk. Otherwise, efforts to improve forest health may be converting forest conservation services to timber services.

  11. Back to Back: A Focus on Reducing the Logistics Costs and Tax

    Directory of Open Access Journals (Sweden)

    Rogério João Lunkes

    2012-06-01

    Full Text Available The objective is to identify the main aspects related to the operation of Back to Back set out in international trade, which enables reduction of logistics costs and taxes. The operation of Back to Back is an excellent opportunity to increase foreign exchange gain and offer greater flexibility to commercial operations that the business requires. The methodology used in preparing this study was qualitative research according to the characteristics and nature of the problem. From the use of descriptive research study aims to demonstrate the main theoretical aspects underlying the subject in reference. This study aimed to identify the main aspects related to the operation of Back to Back set out in international trade and tax effects in an organization and logistics of industrial electronics segment of the State of Santa Catarina. The study demonstrated that the benefits of the operation of Back to Back is of paramount importance for companies having a positive impact in financial terms by reducing the need for tax payments and logistics costs which affect the processes of import and export. The results presented showed that the company studied the operation of Back to Back is essential for international negotiations.

  12. Reducing cost of repair materials for automatic melt injection furnace. Jido chutoro no hoshuyo zairyohi no sakugen

    Energy Technology Data Exchange (ETDEWEB)

    Yasushita, Y.; Nouchi, T.; Nagano, T.; Tamaru, I.; Hasei, S.; Hamano, K.; Suimizu, T.; Okamoto, M. (Nippon Kokan Pipe Fitting Co. Ltd., Osaka (Japan))

    1992-08-25

    This paper summarizes discussion intended of reducing material cost implemented at a casting department which produces materials for pipe joints covering 600 to 650 models. Targets were placed on reducing the current material cost by 30%, the currently used repair jigs by 30%, as well as reducing repair works and manpower. First, a Pareto chart was sought on monetary amount of materials used, to identify items requiring sizable material costs. Items identified include reduction of amount of heat insulating materials used for sensor protection, slug removal cost, and refractories. With respect to the heat insulating materials, the cut sizes were discussed, and as a result , difference among individuals was eliminated molten face levels were prevented from being positioned too high , and the number of replacement due to damages was reduces. The rate of heat insulating material reduction was 39%. As regards the slug removal cost, the cost was reduced by reusing waste materials, the inductor channels were changed, and the method of operating the automatic molten metal pouring furnace was improved. With regard to the refractories, the shell width of troughs was covered with steel plates to reduce the use amount, the replacement manpower was reduced, and the use of expensive refractories was minimized. 10 figs., 5 tabs.

  13. Recycling Flight Hardware Components and Systems to Reduce Next Generation Research Costs

    Science.gov (United States)

    Turner, Wlat

    2011-01-01

    With the recent 'new direction' put forth by President Obama identifying NASA's new focus in research rather than continuing on a path to return to the Moon and Mars, the focus of work at Kennedy Space Center (KSC) may be changing dramatically. Research opportunities within the micro-gravity community potentially stands at the threshold of resurgence when the new direction of the agency takes hold for the next generation of experimenters. This presentation defines a strategy for recycling flight experiment components or part numbers, in order to reduce research project costs, not just in component selection and fabrication, but in expediting qualification of hardware for flight. A key component of the strategy is effective communication of relevant flight hardware information and available flight hardware components to researchers, with the goal of 'short circuiting' the design process for flight experiments

  14. Cesarean Delivery Rates Vary 10-Fold Among US Hospitals; Reducing Variation May Address Quality, Cost Issues

    Science.gov (United States)

    Kozhimannil, Katy Backes; Law, Michael R.; Virnig, Beth A.

    2013-01-01

    Cesarean delivery is the most commonly performed surgical procedure in the United States, and cesarean rates are increasing. Working with 2009 data from 593 US hospitals nationwide, we found that cesarean rates varied tenfold across hospitals, from 7.1 percent to 69.9 percent. Even for women with lower-risk pregnancies, in which more limited variation might be expected, cesarean rates varied fifteen-fold, from 2.4 percent to 36.5 percent. Thus, vast differences in practice patterns are likely to be driving the costly overuse of cesarean delivery in many US hospitals. Because Medicaid pays for nearly half of US births, government efforts to decrease variation are warranted. We focus on four promising directions for reducing these variations, including better coordination of maternity care, more data collection and measurement, tying Medicaid payment to quality improvement, and enhancing patient-centered decision making through public reporting. PMID:23459732

  15. Enhanced methods for operating refueling station tube-trailers to reduce refueling cost

    Energy Technology Data Exchange (ETDEWEB)

    Elgowainy, Amgad; Reddi, Krishna

    2017-08-22

    A method and apparatus are provided for operating a refueling station including source tube-trailers and at least one compressor to reduce refueling cost. The refueling station includes a gaseous fuel supply source including a plurality of tanks on a tube trailer coupled to a first control unit, and high pressure buffer storage having predefined capacity coupled to a second control unit and the first tanks by a pressure control valve and the first control unit, and at least one compressor. The refueling station is operated at different modes depending on a state of the refueling station at the beginning of each operational mode. The refueling system is assessed at the end of each operational mode to identify the state of the system and select a next mode of operation. The operational modes include consolidating hydrogen, or any gaseous fuel, within the tubes mounted on the trailer.

  16. Synthesis of medicinally relevant terpenes: reducing the cost and time of drug discovery.

    Science.gov (United States)

    Jansen, Daniel J; Shenvi, Ryan A

    2014-06-01

    Terpenoids constitute a significant fraction of molecules produced by living organisms that have found use in medicine and other industries. Problems associated with their procurement and adaptation for human use can be solved using chemical synthesis, which is an increasingly economical option in the modern era of chemistry. This article documents, by way of individual case studies, strategies for reducing the time and cost of terpene synthesis for drug discovery. A major trend evident in recent syntheses is that complex terpenes are increasingly realistic starting points for both medicinal chemistry campaigns and large-scale syntheses, at least in the context of the academic laboratory, and this trend will likely penetrate the commercial sector in the near future.

  17. Dark chocolate supplementation reduces the oxygen cost of moderate intensity cycling.

    Science.gov (United States)

    Patel, Rishikesh Kankesh; Brouner, James; Spendiff, Owen

    2015-01-01

    Dark chocolate (DC) is abundant in flavanols which have been reported to increase the bioavailability and bioactivity of nitric oxide (NO). Increasing NO bioavailability has often demonstrated reduced oxygen cost and performance enhancement during submaximal exercise. Nine moderately-trained male participants volunteered to undertake baseline (BL) measurements that comprised a cycle V̇O(2max) test followed by cycling at 80% of their established gas exchange threshold (GET) for 20-min and then immediately followed by a two-minute time-trial (TT). Using a randomised crossover design participants performed two further trials, two weeks apart, with either 40 g of DC or white chocolate (WC) being consumed daily. Oxygen consumption, RER, heart rate and blood lactate (BLa) were measured during each trial. DC consumption increased GET and TT performance compared to both BL and WC (P < 0.05). DC consumption increased V̇O(2max) by 6% compared to BL (P < 0.05), but did not reach statistical significance compared to WC. There were no differences in the moderate-intensity cycling for V̇O₂, RER, BLa and heart rate between conditions, although, V̇O₂ and RER exhibited consistently lower trends following DC consumption compared to BL and WC, these did not reach statistical significance. Chronic supplementation with DC resulted in a higher GET and enhanced TT performance. Consequently, ingestion of DC reduced the oxygen cost of moderate intensity exercise and may be an effective ergogenic aid for short-duration moderate intensity exercise.

  18. Reducing Nitrogen Pollution while Decreasing Farmers' Costs and Increasing Fertilizer Industry Profits.

    Science.gov (United States)

    Kanter, David R; Zhang, Xin; Mauzerall, Denise L

    2015-03-01

    Nitrogen (N) pollution is emerging as one of the most important environmental issues of the 21st Century, contributing to air and water pollution, climate change, and stratospheric ozone depletion. With agriculture being the dominant source, we tested whether it is possible to reduce agricultural N pollution in a way that benefits the environment, reduces farmers' costs, and increases fertilizer industry profitability, thereby creating a "sweet spot" for decision-makers that could significantly increase the viability of improved N management initiatives. Although studies of the economic impacts of improved N management have begun to take into account farmers and the environment, this is the first study to consider the fertilizer industry. Our "sweet spot" hypothesis is evaluated via a cost-benefit analysis of moderate and ambitious N use efficiency targets in U.S. and China corn sectors over the period 2015-2035. We use a blend of publicly available crop and energy price projections, original time-series modeling, and expert elicitation. The results present a mixed picture: although the potential for a "sweet spot" exists in both countries, it is more likely that one occurs in China due to the currently extensive overapplication of fertilizer, which creates a greater potential for farmers and the fertilizer industry to gain economically from improved N management. Nevertheless, the environmental benefits of improving N management consistently dwarf the economic impacts on farmers and the fertilizer industry in both countries, suggesting that viable policy options could include incentives to farmers and the fertilizer industry to increase their support for N management policies.

  19. Human Responding on Random-Interval Schedules of Response-Cost Punishment: The Role of Reduced Reinforcement Density

    Science.gov (United States)

    Pietras, Cynthia J.; Brandt, Andrew E.; Searcy, Gabriel D.

    2010-01-01

    An experiment with adult humans investigated the effects of response-contingent money loss (response-cost punishment) on monetary-reinforced responding. A yoked-control procedure was used to separate the effects on responding of the response-cost contingency from the effects of reduced reinforcement density. Eight adults pressed buttons for money…

  20. Advanced Manufacturing Process for Lower Cost Rechargeable Lithium-ion Batteries for DOD Including the BB2590

    Science.gov (United States)

    2013-11-30

    Nickelate in 18650 Cell 24 8. Installation of Resistance Welder 25 9. Bi-Cell Vacuum Dryer and with Activation Box 26 10. Semi...DOD lithium-ion rechargeable cells/batteries are composed of combinations using Asian 18650 cells including the BB2590. This dependence is due to the...much lower cost of the Asian and particularly the Chinese 18650 cells which are made on very large scale and also with lower labor costs. LithChem

  1. Dynamic Cost-Contingency Management: A Method for Reducing Project Costs While Increasing the Probability of Success

    Science.gov (United States)

    2007-04-30

    with Goldratt’s observation that negative human behavior is a major cause of the project-scheduling problem. Goldratt (1997) developed the Critical...2002). Assessment of cost uncertainties for large technology projects: A methodology and an application. Interfaces 32(4), 52-66. Goldratt , E.M

  2. A cost-effectiveness analysis of reducing ventilator-associated pneumonia at a Danish ICU with ventilator bundle

    DEFF Research Database (Denmark)

    Møller, Anders Holmen; Hansen, Louise; Jensen, Morten Sall;

    2012-01-01

    -based routine treatment or standard procedures. OBJECTIVE: To determine cost-effectiveness of implementing the Ventilator bundle (VB), thereby reducing ventilator-associated pneumonia (VAP), when treating a ventilated patient, compared to standard procedure. SETTING AND PATIENTS: A hypothetical population...

  3. The Capital Intensity of Photovoltaics Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Basore, Paul

    2015-10-19

    Factory capital expenditure (capex) for photovoltaic (PV) module manufacturing strongly influences the per-unit cost of a c-Si module. This provides a significant opportunity to address the U.S. DOE SunShot module price target through capex innovation. Innovation options to reduce the capex of PV manufacturing include incremental and disruptive process innovation with c-Si, platform innovations, and financial approaches. and financial approaches.

  4. Reducing rotor weight

    Energy Technology Data Exchange (ETDEWEB)

    Cheney, M.C. [PS Enterprises, Inc., Glastonbury, CT (United States)

    1997-12-31

    The cost of energy for renewables has gained greater significance in recent years due to the drop in price in some competing energy sources, particularly natural gas. In pursuit of lower manufacturing costs for wind turbine systems, work was conducted to explore an innovative rotor designed to reduce weight and cost over conventional rotor systems. Trade-off studies were conducted to measure the influence of number of blades, stiffness, and manufacturing method on COE. The study showed that increasing number of blades at constant solidity significantly reduced rotor weight and that manufacturing the blades using pultrusion technology produced the lowest cost per pound. Under contracts with the National Renewable Energy Laboratory and the California Energy Commission, a 400 kW (33m diameter) turbine was designed employing this technology. The project included tests of an 80 kW (15.5m diameter) dynamically scaled rotor which demonstrated the viability of the design.

  5. Reducing the energy cost of human walking using an unpowered exoskeleton.

    Science.gov (United States)

    Collins, Steven H; Wiggin, M Bruce; Sawicki, Gregory S

    2015-06-11

    With efficiencies derived from evolution, growth and learning, humans are very well-tuned for locomotion. Metabolic energy used during walking can be partly replaced by power input from an exoskeleton, but is it possible to reduce metabolic rate without providing an additional energy source? This would require an improvement in the efficiency of the human-machine system as a whole, and would be remarkable given the apparent optimality of human gait. Here we show that the metabolic rate of human walking can be reduced by an unpowered ankle exoskeleton. We built a lightweight elastic device that acts in parallel with the user's calf muscles, off-loading muscle force and thereby reducing the metabolic energy consumed in contractions. The device uses a mechanical clutch to hold a spring as it is stretched and relaxed by ankle movements when the foot is on the ground, helping to fulfil one function of the calf muscles and Achilles tendon. Unlike muscles, however, the clutch sustains force passively. The exoskeleton consumes no chemical or electrical energy and delivers no net positive mechanical work, yet reduces the metabolic cost of walking by 7.2 ± 2.6% for healthy human users under natural conditions, comparable to savings with powered devices. Improving upon walking economy in this way is analogous to altering the structure of the body such that it is more energy-effective at walking. While strong natural pressures have already shaped human locomotion, improvements in efficiency are still possible. Much remains to be learned about this seemingly simple behaviour.

  6. Wire + Arc Additive Manufacturing

    OpenAIRE

    Williams, Stewart W.; Martina, Filomeno; Addison, Adrian C.; Ding, Jialuo; Pardal, Goncalo; Colegrove, Paul A.

    2016-01-01

    Depositing large components (>10 kg) in titanium, aluminium, steel and other metals is possible using Wire + Arc Additive Manufacturing. This technology adopts arc welding tools and wire as feedstock for additive manufacturing purposes. High deposition rates, low material and equipment costs, and good structural integrity make Wire+Arc Additive Manufacturing a suitable candidate for replacing the current method of manufacturing from solid billets or large forgings, especially with regards to ...

  7. Reducing health disparities by removing cost, access, and knowledge barriers.

    Science.gov (United States)

    Goodman, Melody; Onwumere, Ojiugo; Milam, Laurel; Peipert, Jeffrey F

    2017-04-01

    While the rate of unintended pregnancy has declined in the United States in recent years, unintended pregnancy among teens in the United States is the highest among industrialized nations, and disproportionately affects minority teens. Our objective of this secondary analysis was to estimate the risk of unintended pregnancy for both Black and White teens age 15-19 years when barriers to access, cost, and knowledge are removed. Our hypothesis was that the Black-White disparities would be reduced when access, education, and cost barriers are removed. We performed an analysis of the Contraceptive CHOICE Project database. CHOICE is a longitudinal cohort study of 9256 sexually active girls and women ages 14-45 years in the St Louis, MO, region from 2007 through 2013. Two measures of disparities were used to analyze teenage pregnancy rates and pregnancy risk from 2008 through 2013 among teens ages 15-19 years. These rates were then compared to the rates of pregnancy among all sexually active teens in the United States during the years 2008, 2009, 2010, and 2011. We estimated an absolute measure (rate difference) and a relative measure (rate ratio) to examine Black-White disparities in the rates of unintended pregnancy. While national rates of unintended pregnancy are decreasing, racial disparities in these rates persist. The Black-White rate difference dropped from 158.5 per 1000 in 2008 to 120.1 per 1000 in 2011; however, the relative ratio disparity decreased only from 2.6-2.5, suggesting that Black sexually active teens in the United States have 2.5 times the rate of unintended pregnancy as White teenagers. In the CHOICE Project, there was a decreasing trend in racial disparities in unintended pregnancy rates among sexually active teens (age 15-19 years): 2008 through 2009 (rate difference, 18.2; rate ratio, 3.7), 2010 through 2011 (rate difference, 4.3; rate ratio, 1.2), and 2012 through 2013 (rate difference, -1.5; rate ratio, 1.0). When barriers to cost, access

  8. Reduced use of erythropoiesis-stimulating agents and intravenous iron with ferric citrate: a managed care cost-offset model

    Directory of Open Access Journals (Sweden)

    Mutell R

    2013-04-01

    Full Text Available Richard Mutell, Jaime L Rubin, T Christopher Bond, Tracy Mayne DaVita Clinical Research, Minneapolis, MN, USA Background: Ferric citrate (FC is a phosphate binder in development for the treatment of hyperphosphatemia in patients with end-stage renal disease (ESRD. In clinical trials, FC improved patient serum phosphorus levels and increased serum ferritin and percent transferrin saturation. Because nephrologists respond to increases in these iron measures by reducing intravenous (IV iron and erythropoiesis-stimulating agent (ESA doses, the decreased use of iron and ESA associated with FC may reduce costs. Objectives: To develop a cost-offset model from a managed care perspective estimating the cost savings associated with FC use. Methods: We created a cost-offset model from the managed care payer perspective that compared the treatment costs of ESRD for patients given FC. The model considered the number of dialysis sessions per month; number of ESRD patients enrolled in the health plan; cost of ESAs, iron, and dialysis sessions; and the proportion of patients on phosphate binder therapy. The model assumed equivalent efficacy and cost neutrality between FC and other phosphate binders. Monte Carlo simulations were conducted by varying model inputs. Results: When FC was compared to other phosphate binders, the monthly cost of ESA and IV iron per 500 patients with ESRD (85% treated with phosphate binders was reduced by 8.15% and 33.2%, respectively. When incorporated into the total cost of dialysis for patients with ESRD (dialysis, ESA, and IV iron, the decrease in the monthly cost of dialysis care was US$80,214 per 500 ESRD patients. Monte Carlo simulations suggest that a plan serving 500 dialysis patients could save between US$626,000 and US$1,106,000 annually with the use of FC. Conclusion: The use of FC in ESRD patients with hyperphosphatemia may help reduce treatment costs. Keywords: phosphate binders, hyperphosphatemia, end-stage renal disease

  9. Reduced use of erythropoiesis-stimulating agents and intravenous iron with ferric citrate: a managed care cost-offset model.

    Science.gov (United States)

    Mutell, Richard; Rubin, Jaime L; Bond, T Christopher; Mayne, Tracy

    2013-01-01

    Ferric citrate (FC) is a phosphate binder in development for the treatment of hyperphosphatemia in patients with end-stage renal disease (ESRD). In clinical trials, FC improved patient serum phosphorus levels and increased serum ferritin and percent transferrin saturation. Because nephrologists respond to increases in these iron measures by reducing intravenous (IV) iron and erythropoiesis-stimulating agent (ESA) doses, the decreased use of iron and ESA associated with FC may reduce costs. To develop a cost-offset model from a managed care perspective estimating the cost savings associated with FC use. We created a cost-offset model from the managed care payer perspective that compared the treatment costs of ESRD for patients given FC. The model considered the number of dialysis sessions per month; number of ESRD patients enrolled in the health plan; cost of ESAs, iron, and dialysis sessions; and the proportion of patients on phosphate binder therapy. The model assumed equivalent efficacy and cost neutrality between FC and other phosphate binders. Monte Carlo simulations were conducted by varying model inputs. When FC was compared to other phosphate binders, the monthly cost of ESA and IV iron per 500 patients with ESRD (85% treated with phosphate binders) was reduced by 8.15% and 33.2%, respectively. When incorporated into the total cost of dialysis for patients with ESRD (dialysis, ESA, and IV iron), the decrease in the monthly cost of dialysis care was US$80,214 per 500 ESRD patients. Monte Carlo simulations suggest that a plan serving 500 dialysis patients could save between US$626,000 and US$1,106,000 annually with the use of FC. The use of FC in ESRD patients with hyperphosphatemia may help reduce treatment costs.

  10. Life-cycle and cost of goods assessment of fed-batch and perfusion-based manufacturing processes for mAbs.

    Science.gov (United States)

    Bunnak, Phumthep; Allmendinger, Richard; Ramasamy, Sri V; Lettieri, Paola; Titchener-Hooker, Nigel J

    2016-09-01

    Life-cycle assessment (LCA) is an environmental assessment tool that quantifies the environmental impact associated with a product or a process (e.g., water consumption, energy requirements, and solid waste generation). While LCA is a standard approach in many commercial industries, its application has not been exploited widely in the bioprocessing sector. To contribute toward the design of more cost-efficient, robust and environmentally-friendly manufacturing process for monoclonal antibodies (mAbs), a framework consisting of an LCA and economic analysis combined with a sensitivity analysis of manufacturing process parameters and a production scale-up study is presented. The efficiency of the framework is demonstrated using a comparative study of the two most commonly used upstream configurations for mAb manufacture, namely fed-batch (FB) and perfusion-based processes. Results obtained by the framework are presented using a range of visualization tools, and indicate that a standard perfusion process (with a pooling duration of 4 days) has similar cost of goods than a FB process but a larger environmental footprint because it consumed 35% more water, demanded 17% more energy, and emitted 17% more CO2 than the FB process. Water consumption was the most important impact category, especially when scaling-up the processes, as energy was required to produce process water and water-for-injection, while CO2 was emitted from energy generation. The sensitivity analysis revealed that the perfusion process can be made more environmentally-friendly than the FB process if the pooling duration is extended to 8 days. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 32:1324-1335, 2016. © 2016 The Authors Biotechnology Progress published by Wiley Periodicals, Inc. on behalf of American Institute of Chemical Engineers.

  11. Novel manufacturing techniques for microstructured reactors in industrial dimensions

    OpenAIRE

    Krtschil, Ulrich; Hofmann, Christian; Löb, Patrick; Schütt, Christian; Schorcht, Peter; Streuber, Michael

    2013-01-01

    The results of the development of novel manufacturing techniques for microstructured reactors in the framework of the European project CoPIRIDE are reported. The work was aimed at promoting the application of microstructured chemical reactors in the chemical industry. This can be achieved by completely new ways of production of microstructured plates, as manufactured by the roll embossing technique. This opens the door to mass manufacturing capability, which is a common enabler for cost reduc...

  12. 论企业成本及降低成本的几种途径%On Enterprise Cost and Several Ways of Reducing En-terprise Cost

    Institute of Scientific and Technical Information of China (English)

    崔小艳

    2014-01-01

    我国企业管理者忽视了以全局的高度来审视企业成本,而真正的控制点是经济成本。成本的经济实质决定了成本在经济管理工作中具有十分重要的作用,降低成本对企业的经营效益至关重要。因此,公司需要从单纯控制自身的经营成本,转向与战略成本共同管理控制。在控制成本的途径中,通过基本途径和战略途径来减低企业成本,如实行成本否决,提高劳动生产率,选择规模效应,均衡生产作业和调节市场需求波动,长期维持、巩固成本优势等方法来进行控制。成本管理工作是企业经营管理的核心,是企业增加盈利的根本途径,直接服务于企业的目的。%Chinese enterprise managers have ignored the inspec-tion of enterprise cost from an overall level, while the real control point is economic cost. The economic essence of cost determines the importance of cost in economic management, so reducing cost plays a crucial role in the economic benefits of an enterprise. Therefore, the enterprise should transform from the mere control of operating cost to the management and control of both operating cost and strategic cost. In ways of cost control, basic ways and strategic ways can be used to reduce enterprise cost, such as im-plementing cost rejection, improving productivity of labor, choos-ing scale effect, balancing production, adjusting the fluctuation of market demand, maintaining and consolidating cost advantage over a long period of time. Cost management is the core of enter-prise operation and management, as well as the basic way of in-creasing profits, and it directly serves enterprise goals.

  13. U.S. Wind Energy Manufacturing & Supply Chain: A Competitive Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Fullenkamp, Patrick [Global WindNetwork, Cleveland, OH (United States)

    2014-06-15

    The Global Wind Network (GLWN) assessed the key factors that determine wind energy component manufacturing costs and pricing on a global basis in order to provide a better understanding of the factors that will help enhance the competitiveness of U.S. manufacturers, and reduce installed system costs.

  14. Detectors with Improved Near-to-Mid IR Performance and Reduced Cooling Requirements Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This program will develop an ultra-high performance infrared detector manufacturing technology with improved performance and cost effectiveness, and reduced cooling...

  15. Does NGAL reduce costs? A cost analysis of urine NGAL (uNGAL) & serum creatinine (sCr) for acute kidney injury (AKI) diagnosis.

    Science.gov (United States)

    Parikh, Amay; Rizzo, John A; Canetta, Pietro; Forster, Catherine; Sise, Meghan; Maarouf, Omar; Singer, Eugenia; Elger, Antje; Elitok, Saban; Schmidt-Ott, Kai; Barasch, Jonathon; Nickolas, Thomas L

    2017-01-01

    Urine neutrophil gelatinase-associated lipocalin (uNGAL) is a sensitive and specific diagnostic test for acute kidney injury (AKI) in the Emergency Department (ED), but its economic impact has not been investigated. We hypothesized that uNGAL used in combination with serum creatinine (sCr) would reduce costs in the management of AKI in patients presenting to the ED in comparison to using sCr alone. A cost simulation model was developed for clinical algorithms to diagnose AKI based on sCr alone vs. uNGAL plus sCr (uNGAL+sCr). A cost minimization analysis was performed to determine total expected costs for patients with AKI. uNGAL test characteristics were validated with eight-hundred forty-nine patients with sCr ≥1.5 from a completed study of 1635 patients recruited from EDs at two U.S. hospitals from 2007-8. Biomarker test, AKI work-up, and diagnostic imaging costs were incorporated. For a hypothetical cohort of 10,000 patients, the model predicted that the expected costs were $900 per patient (pp) in the sCr arm and $950 in the uNGAL+sCr arm. uNGAL+sCr resulted in 1,578 fewer patients with delayed diagnosis and treatment than sCr alone (2,013 vs. 436 pts) at center 1 and 1,973 fewer patients with delayed diagnosis and treatment than sCr alone at center 2 (2,227 vs. 254 patients). Although initial evaluation costs at each center were $50 pp higher in with uNGAL+sCr, total costs declined by $408 pp at Center 1 and by $522 pp at Center 2 due to expected reduced delays in diagnosis and treatment. Sensitivity analyses confirmed savings with uNGAL + sCr for a range of cost inputs. Using uNGAL with sCr as a clinical diagnostic test for AKI may improve patient management and reduce expected costs. Any cost savings would likely result from avoiding delays in diagnosis and treatment and from avoidance of unnecessary testing in patients given a false positive AKI diagnosis by use of sCr alone.

  16. Evaluation of Fermented Sausages Manufactured with Reduced-fat and Functional Starter Cultures on Physicochemical, Functional and Flavor Characteristics

    OpenAIRE

    Kim, Young Joo; Park,Sung Yong; Lee, Hong Cheol; Yoo, Seung Seok; Oh, Se Jong; Kim, Hyeong Sang; Chin, Koo Bok

    2014-01-01

    Fermented foods with probiotics having functional properties may provide beneficial effects on health. These effects are varied, depending on the type of lactic acid bacteria (LAB). Different probiotic LAB might have different functional properties. Thus, this study was performed to evaluate the quality of fermented sausages manufactured with functional starter cultures (Lactobacillus plantarum 115 and 167, and Pediococcus damnosus L12) and different fat levels, and to determine the optimum c...

  17. Talking about how to strengthen cost management and reduce project cost%谈如何加强成本管理降低项目成本

    Institute of Scientific and Technical Information of China (English)

    李元英

    2011-01-01

    This paper summarizes many building construction project cost management experience, describes cost influences and controlling from aspects of organization setting, cost check, technological progress, quality and security etc, and proposes several measures on how to reduce project cost, with a view to improve enterprise economic benefits.%总结了众多建筑施工项目成本管理的经验,从机构设置、成本核算、技术进步、质量和安全等方面对成本的影响和控制进行了阐述,提出了如何降低项目成本的几个措施,以提高企业经济效益。

  18. Creative Shenzhen? A critical view on Shenzhen's transformation from a low-cost manufacturing hub to a creative megacity

    NARCIS (Netherlands)

    Bontje, M.

    2014-01-01

    Since 1980, Shenzhen has grown in a record-breaking pace to the megacity it is today. Initially, Shenzhen’s growth was based on low-cost mass industrial production. In recent years, however, the Shenzhen city government is trying to modernize and diversify its economy. Shenzhen has embraced the crea

  19. Creative Shenzhen? A critical view on Shenzhen's transformation from a low-cost manufacturing hub to a creative megacity

    NARCIS (Netherlands)

    Bontje, M.

    2014-01-01

    Since 1980, Shenzhen has grown in a record-breaking pace to the megacity it is today. Initially, Shenzhen’s growth was based on low-cost mass industrial production. In recent years, however, the Shenzhen city government is trying to modernize and diversify its economy. Shenzhen has embraced the crea

  20. Technical cost modelling for a novel semi-solid metal (SSM) casting processes for automotive component manufacturing

    CSIR Research Space (South Africa)

    Tlale, NS

    2008-09-01

    Full Text Available The cost structure and benefits of a new billet preparation process in semi-solid metal (SSM) casting of automotive components were investigated. The process was developed by the CSIR, a government research and development agency in South Africa...

  1. Multiple EFG silicon ribbon technology as the basis for manufacturing low-cost terrestrial solar cells. [Epitaxial Film Growth

    Science.gov (United States)

    Mackintosh, B.; Kalejs, J. P.; Ho, C. T.; Wald, F. V.

    1981-01-01

    Mackintosh et al. (1978) have reported on the development of a multiple ribbon furnace based on the 'edge defined film fed growth' (EFG) process for the fabrication of silicon ribbon. It has been demonstrated that this technology can meet the requirements for a silicon substrate material to be used in the manufacture of solar panels which can meet requirements regarding a selling price of $0.70/Wp when certain goals in terms of throughput and quality are achieved. These goals for the multiple ribbon technology using 10 cm wide ribbon require simultaneous growth of 12 ribbons by one operator at average speeds of 4 to 4.5 cm/min, and 13% efficient solar cells. A description is presented of the progress made toward achieving these goals. It is concluded that the required performance levels have now been achieved. The separate aspects of technology must now be integrated into a single prototype furnace.

  2. Cost and Performance Report Low Impact Technologies to Reduce Pollution from Storm Water Runoff SI-200405

    Science.gov (United States)

    2008-09-01

    and will likely require earthwork to remove the lids over the media bed. 44 5.2 Cost Analysis The economic analysis performed on the NRRC dual...pump system. Given these two scenarios, the economic evaluation was constructed and compared. 5.3.2 Cost Drivers The cost of the implementing a...report 7374 National Defense Center for Enviromental Exellence, 1999, Environmental Cost Analysis Methodology (CECAM) handbook, March 29, 1999

  3. A Partnership between Value Engineering and the Diminishing Manufacturing Sources and Material Shortages Community to Reduce Ownership Costs

    Science.gov (United States)

    2008-09-01

    Engineering Proposals ( VEPs ) and Value Engineering Change Proposals (VECPs). A VEP is a specific proposal developed internally by DoD personnel for...total value improvement from the use of VE techniques. Since VEPs are developed and implemented by Government personnel, all resulting savings...accrue to the Government. A VEP can also be the result of a technical support contractor effort if it is funded by the Government specifically to

  4. Cost-effectiveness analysis of salt reduction policies to reduce coronary heart disease in Syria, 2010-2020.

    Science.gov (United States)

    Wilcox, Meredith L; Mason, Helen; Fouad, Fouad M; Rastam, Samer; al Ali, Radwan; Page, Timothy F; Capewell, Simon; O'Flaherty, Martin; Maziak, Wasim

    2015-01-01

    This study presents a cost-effectiveness analysis of salt reduction policies to lower coronary heart disease in Syria. Costs and benefits of a health promotion campaign about salt reduction (HP); labeling of salt content on packaged foods (L); reformulation of salt content within packaged foods (R); and combinations of the three were estimated over a 10-year time frame. Policies were deemed cost-effective if their cost-effectiveness ratios were below the region's established threshold of $38,997 purchasing power parity (PPP). Sensitivity analysis was conducted to account for the uncertainty in the reduction of salt intake. HP, L, and R+HP+L were cost-saving using the best estimates. The remaining policies were cost-effective (CERs: R=$5,453 PPP/LYG; R+HP=$2,201 PPP/LYG; R+L=$2,125 PPP/LYG). R+HP+L provided the largest benefit with net savings using the best and maximum estimates, while R+L was cost-effective with the lowest marginal cost using the minimum estimates. This study demonstrated that all policies were cost-saving or cost effective, with the combination of reformulation plus labeling and a comprehensive policy involving all three approaches being the most promising salt reduction strategies to reduce CHD mortality in Syria.

  5. A Comparison of Response Cost and Differential Reinforcement of Other Behavior to Reduce Disruptive Behavior in a Preschool Classroom

    Science.gov (United States)

    Conyers, Carole; Miltenberger, Raymond; Maki, Amber; Barenz, Rebecca; Jurgens, Mandy; Sailer, Angela; Haugen, Meredith; Kopp, Brandon

    2004-01-01

    This study investigated the effectiveness of response cost and differential reinforcement of other behavior (DRO) in reducing the disruptive behaviors of 25 children in a preschool classroom. Using an alternating treatments design, disruptive behavior was reduced when the participants earned tokens for the absence of disruptive behavior (DRO) or…

  6. Capsiate supplementation reduces oxidative cost of contraction in exercising mouse skeletal muscle in vivo.

    Directory of Open Access Journals (Sweden)

    Kazuya Yashiro

    Full Text Available Chronic administration of capsiate is known to accelerate whole-body basal energy metabolism, but the consequences in exercising skeletal muscle remain very poorly documented. In order to clarify this issue, the effect of 2-week daily administration of either vehicle (control or purified capsiate (at 10- or 100-mg/kg body weight on skeletal muscle function and energetics were investigated throughout a multidisciplinary approach combining in vivo and in vitro measurements in mice. Mechanical performance and energy metabolism were assessed strictly non-invasively in contracting gastrocnemius muscle using magnetic resonance (MR imaging and 31-phosphorus MR spectroscopy (31P-MRS. Regardless of the dose, capsiate treatments markedly disturbed basal bioenergetics in vivo including intracellular pH alkalosis and decreased phosphocreatine content. Besides, capsiate administration did affect neither mitochondrial uncoupling protein-3 gene expression nor both basal and maximal oxygen consumption in isolated saponin-permeabilized fibers, but decreased by about twofold the Km of mitochondrial respiration for ADP. During a standardized in vivo fatiguing protocol (6-min of repeated maximal isometric contractions electrically induced at a frequency of 1.7 Hz, both capsiate treatments reduced oxidative cost of contraction by 30-40%, whereas force-generating capacity and fatigability were not changed. Moreover, the rate of phosphocreatine resynthesis during the post-electrostimulation recovery period remained unaffected by capsiate. Both capsiate treatments further promoted muscle mass gain, and the higher dose also reduced body weight gain and abdominal fat content. These findings demonstrate that, in addition to its anti-obesity effect, capsiate supplementation improves oxidative metabolism in exercising muscle, which strengthen this compound as a natural compound for improving health.

  7. The role of photoperiods on photobioreactors - A potential strategy to reduce costs.

    Science.gov (United States)

    Maroneze, Mariana Manzoni; Siqueira, Stefania Fortes; Vendruscolo, Raquel Guidetti; Wagner, Roger; de Menezes, Cristiano Ragagnin; Zepka, Leila Queiroz; Jacob-Lopes, Eduardo

    2016-11-01

    The aim of this work was evaluate the role of photoperiods (long-term, frequencies and short) on the growth and lipid content of microalgae Scenedesmus obliquus CPCC05. The results showed that Scenedesmus obliquus can store sufficient energy to sustain cell growth for continuous periods of up to 2h in the dark, without affecting the photosynthetic rate. The values for maximum biomass (9.58mg/Lh) and lipid productivities (2.56mg/Lh) were obtained at photoperiod of 0.91:0.09s (light:dark) and 48 t/d, respectively. Moreover, the best trade-offs between biomass productivity and light energy economy occurred in photoperiods of 0.5:0.5s and 0.91:0.09s (light:dark), and those between lipid productivity and light energy economy occurred in the frequency photoperiod of 24 and 48 t/d. Thus, the use of the photoperiods are an effective strategy for reducing costs of microalgal biomass production.

  8. Assessment of xylanase activity in dry storage as a potential method of reducing feedstock cost.

    Science.gov (United States)

    Smith, William A; Thompson, David N; Thompson, Vicki S; Radtke, Corey W; Carter, Brady

    2009-05-01

    Enzymatic preprocessing of lignocellulosic biomass in dry storage systems has the potential to improve feedstock characteristics and lower ethanol production costs. To assess the potential for endoxylanase activity at low water contents, endoxylanase activity was tested using a refined wheat arabinoxylan substrate and three commercial endoxylanases over the water activity range 0.21-1.0, corresponding to water contents of 5% to >60% (dry basis). Homogeneously mixed dry samples were prepared at a fixed enzyme to substrate ratio and incubated in chambers at a variety of fixed water activities. Replicates were sacrificed periodically, and endoxylanase activity was quantified as an increase in reducing sugar relative to desiccant-stored controls. Endoxylanase activity was observed at water activities over 0.91 in all enzyme preparations in less than 4 days and at a water activity of 0.59 in less than 1 week in two preparations. Endoxylanase activity after storage was confirmed for selected desiccant-stored controls by incubation at 100% relative humidity. Water content to water activity relationships were determined for three lignocellulosic substrates, and results indicate that two endoxylanase preparations retained limited activity as low as 7% to 13% water content (dry basis), which is well within the range of water contents representative of dry biomass storage. Future work will examine the effects of endoxylanase activity toward substrates such as corn stover, wheat straw, and switchgrass in low water content environments.

  9. Selection for reduced translation costs at the intronic 5′ end in fungi

    Science.gov (United States)

    Zafrir, Zohar; Zur, Hadas; Tuller, Tamir

    2016-01-01

    It is generally believed that introns are not translated; therefore, the potential intronic features that may be related to the translation step (occurring after splicing) have yet to be thoroughly studied. Here, focusing on four fungi, we performed for the first time a comprehensive study aimed at characterizing how translation efficiency is encoded in introns and affects their evolution. By analysing their intronome we provide evidence of selection for STOP codons close to the intronic 5′ end, and show that the beginning of introns are selected for significantly high translation, presumably to reduce translation and metabolic costs in cases of non-spliced introns. Ribosomal profiling data analysis in Saccharomyces cerevisiae supports the conjecture that in this organism intron retention frequently occurs, introns are partially translated, and their translation efficiency affects organismal fitness. We show that the reported results are more significant in highly translated and highly spliced genes, but are not associated only with genes with a specific function. We also discuss the potential relation of the reported signals to efficient nonsense-mediated decay due to splicing errors. These new discoveries are supported by population-genetics considerations. In addition, they are contributory steps towards a broader understanding of intron evolution and the effect of silent mutations on gene expression and organismal fitness. PMID:27260512

  10. The AskIT Service Desk: A Model for Improving Productivity and Reducing Costs

    Energy Technology Data Exchange (ETDEWEB)

    Ashcraft, Phillip Lynn [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fogle, Blythe G. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cummings, Susan M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lopez, Leon [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-07-29

    This was prepared for the business process improvement presentation to the Department of Energy. Los Alamos National Laboratory provides a single point of contact, the AskIT Service Desk, to address issues that impact customer productivity. At the most basic level, what customers want is for their calls to be received, to get a response from a knowledgeable analyst, and to have their issues resolved and their requests fulfilled. Providing a centralized, single point of contact service desk makes initiating technical or business support simple for the customer and improves the odds of immediately resolving the issue or correctly escalating the request to the next support level when necessary. Fulfilling customer requests through automated workflow also improves customer productivity and reduces costs. Finally, customers should be provided the option to solve their own problems through easy access to self-help resources such as frequently asked questions (FAQs) and how-to guides. To accomplish this, everyone who provides and supports services must understand how these processes and functions work together. Service providers and those who support services must “speak the same language” and share common objectives. The Associate Directorate for Business Innovation (ADBI) began the journey to improve services by selecting a known service delivery framework (Information Technology Infrastructure Library, or ITIL). From this framework, components that contribute significant business value were selected.

  11. Rapid growth cost in "all-fish" growth hormone gene transgenic carp: Reduced critical swimming speed

    Institute of Scientific and Technical Information of China (English)

    LI DeLiang; FU CuiZhang; HU Wei; ZHONG Shan; WANG YaPing; ZHU ZuoYan

    2007-01-01

    Evidence has accumulated that there is a trade-off between benefits and costs associated with rapid growth. A trade-off between growth rates and critical swimming speed (Ucrit) had been also reported to be common in teleost fish. We hypothesize that growth acceleration in the F3 generation of "all-fish"growth hormone gene (GH) transgenic common carp (Cyprinus carpio L.) would reduce the swimming abilities. Growth and swimming performance between transgenic fish and non-transgenic controls were compared. The results showed that transgenic fish had a mean body weight 1.4-1.9-fold heavier,and a mean specific growth rate (SGR) value 6%-10% higher than the controls. Transgenic fish,however, had a mean absolute Ucrit (cm/s) value 22% or mean relative Ucrit (BL/s) value 24% lower than the controls. It suggested that fast-growing "all-fish" GH-transgenic carp were inferior swimmers. It is also supported that there was a trade-off between growth rates and swimming performance, i.e.faster-growing individuals had lower critical swimming speed.

  12. Real-time motion analytics during brain MRI improve data quality and reduce costs.

    Science.gov (United States)

    Dosenbach, Nico U F; Koller, Jonathan M; Earl, Eric A; Miranda-Dominguez, Oscar; Klein, Rachel L; Van, Andrew N; Snyder, Abraham Z; Nagel, Bonnie J; Nigg, Joel T; Nguyen, Annie L; Wesevich, Victoria; Greene, Deanna J; Fair, Damien A

    2017-08-10

    Head motion systematically distorts clinical and research MRI data. Motion artifacts have biased findings from many structural and functional brain MRI studies. An effective way to remove motion artifacts is to exclude MRI data frames affected by head motion. However, such post-hoc frame censoring can lead to data loss rates of 50% or more in our pediatric patient cohorts. Hence, many scanner operators collect additional 'buffer data', an expensive practice that, by itself, does not guarantee sufficient high-quality MRI data for a given participant. Therefore, we developed an easy-to-setup, easy-to-use Framewise Integrated Real-time MRI Monitoring (FIRMM) software suite that provides scanner operators with head motion analytics in real-time, allowing them to scan each subject until the desired amount of low-movement data has been collected. Our analyses show that using FIRMM to identify the ideal scan time for each person can reduce total brain MRI scan times and associated costs by 50% or more. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  13. Solvent-free dry powder coating process for low-cost manufacturing of LiNi1/3Mn1/3Co1/3O2 cathodes in lithium-ion batteries

    Science.gov (United States)

    Al-Shroofy, Mohanad; Zhang, Qinglin; Xu, Jiagang; Chen, Tao; Kaur, Aman Preet; Cheng, Yang-Tse

    2017-06-01

    We report a solvent-free dry powder coating process for making LiNi1/3Mn1/3Co1/3O2 (NMC) positive electrodes in lithium-ion batteries. This process eliminates volatile organic compound emission and reduces thermal curing time from hours to minutes. A mixture of NMC, carbon black, and poly(vinylidene difluoride) was electrostatically sprayed onto an aluminum current collector, forming a uniformly distributed electrode with controllable thickness and porosity. Charge/discharge cycling of the dry-powder-coated electrodes in lithium-ion half cells yielded a discharge specific capacity of 155 mAh g-1 and capacity retention of 80% for more than 300 cycles when the electrodes were tested between 3.0 and 4.3 V at a rate of C/5. The long-term cycling performance and durability of dry-powder coated electrodes are similar to those made by the conventional wet slurry-based method. This solvent-free dry powder coating process is a potentially lower-cost, higher-throughput, and more environmentally friendly manufacturing process compared with the conventional wet slurry-based electrode manufacturing method.

  14. Development of technology for thin substrate polycrystalline solar cells for practical use. Development of manufacturing technologies for low-cost substrates (technical development for production of high purity silicon); Usugata takessho taiyo denchi seizo gijutsu no jitsuyoka kenkyu. Tei cost kiban seizo gijutsu kaihatsu (taiyo denchiyo silicon seizo gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    Tatsuta, M. [New Energy and Industrial Technology Development Organization, Tokyo (Japan)

    1994-12-01

    This paper reports the study results on development of manufacturing technologies of Si for solar cells in fiscal 1994. (1) P in Si could be successfully reduced to 0.1ppmw by EB melting method. The condition possible to reduce P in Si while continuously supplying metal Si was found. The 20kg class EB melting equipment was also designed and manufactured which can be connected with solidifying rough refining process. (2) Use of a water-cooling copper mold was studied using a small melting equipment for cost reduction in solidifying rough refining process. As a result, the prospect of crucible-free technology for removal of P and solidifying rough refining was obtained. (3) B in Si could be successfully reduced to the target of 0.1ppmw by vapor addition method using a plasma melting equipment. (4) The prototype SOG-Si achieved a conversion efficiency of 14.1% as solar cell. In addition, the advanced solar cell prepared by efficiency enhancement process achieved a conversion efficiency of 15.9%. 3 figs.

  15. Life‐cycle and cost of goods assessment of fed‐batch and perfusion‐based manufacturing processes for mAbs

    Science.gov (United States)

    Bunnak, Phumthep; Allmendinger, Richard; Ramasamy, Sri V.; Lettieri, Paola

    2016-01-01

    Life‐cycle assessment (LCA) is an environmental assessment tool that quantifies the environmental impact associated with a product or a process (e.g., water consumption, energy requirements, and solid waste generation). While LCA is a standard approach in many commercial industries, its application has not been exploited widely in the bioprocessing sector. To contribute toward the design of more cost‐efficient, robust and environmentally‐friendly manufacturing process for monoclonal antibodies (mAbs), a framework consisting of an LCA and economic analysis combined with a sensitivity analysis of manufacturing process parameters and a production scale‐up study is presented. The efficiency of the framework is demonstrated using a comparative study of the two most commonly used upstream configurations for mAb manufacture, namely fed‐batch (FB) and perfusion‐based processes. Results obtained by the framework are presented using a range of visualization tools, and indicate that a standard perfusion process (with a pooling duration of 4 days) has similar cost of goods than a FB process but a larger environmental footprint because it consumed 35% more water, demanded 17% more energy, and emitted 17% more CO2 than the FB process. Water consumption was the most important impact category, especially when scaling‐up the processes, as energy was required to produce process water and water‐for‐injection, while CO2 was emitted from energy generation. The sensitivity analysis revealed that the perfusion process can be made more environmentally‐friendly than the FB process if the pooling duration is extended to 8 days. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 32:1324–1335, 2016 PMID:27390260

  16. Potential cost-effectiveness of schistosomiasis treatment for reducing HIV transmission in Africa--the case of Zimbabwean women.

    Directory of Open Access Journals (Sweden)

    Martial L Ndeffo Mbah

    Full Text Available BACKGROUND: Epidemiological data from Zimbabwe suggests that genital infection with Schistosoma haematobium may increase the risk of HIV infection in young women. Therefore, the treatment of Schistosoma haematobium with praziquantel could be a potential strategy for reducing HIV infection. Here we assess the potential cost-effectiveness of praziquantel as a novel intervention strategy against HIV infection. METHODS: We developed a mathematical model of female genital schistosomiasis (FGS and HIV infections in Zimbabwe that we fitted to cross-sectional data of FGS and HIV prevalence of 1999. We validated our epidemic projections using antenatal clinic data on HIV prevalence. We simulated annual praziquantel administration to school-age children. We then used these model predictions to perform a cost-effectiveness analysis of annual administration of praziquantel as a potential measure to reduce the burden of HIV in sub-Saharan Africa. FINDINGS: We showed that for a variation of efficacy between 30-70% of mass praziquantel administration for reducing the enhanced risk of HIV transmission per sexual act due to FGS, annual administration of praziquantel to school-age children in Zimbabwe could result in net savings of US$16-101 million compared with no mass treatment of schistosomiasis over a ten-year period. For a variation in efficacy between 30-70% of mass praziquantel administration for reducing the acquisition of FGS, annual administration of praziquantel to school-age children could result in net savings of US$36-92 million over a ten-year period. CONCLUSIONS: In addition to reducing schistosomiasis burden, mass praziquantel administration may be a highly cost-effective way of reducing HIV infections in sub-Saharan Africa. Program costs per case of HIV averted are similar to, and under some conditions much better than, other interventions that are currently implemented in Africa to reduce HIV transmission. As a cost-saving strategy, mass

  17. The role of exhaust ventilation systems in reducing occupational exposure to organic solvents in a paint manufacturing factory

    Directory of Open Access Journals (Sweden)

    Jafari Mohammad

    2008-01-01

    Full Text Available This paper presents the successful design and implementation of several exhaust ventilation systems in a paint manufacturing factory. The ventilation systems were designed based on American Conference of Governmental Industrial Hygienists recommendations. The duct works, fans, and other parts were made and mounted by local manufacturers. The concentrations of toluene and xylene as the common solvents used in paint mixing factories were measured to evaluate the role of ventilation systems in controlling the organic solvents. Occupational exposure to toluene and xylene as the major pollutants was assessed with and without applying ventilation systems. For this purpose, samples were taken from breathing zone of exposed workers using personal samples. The samples were analyzed using Occupational Safety and Health Administration analytical method No.12. The samples were quantified using gas chromatography. The results showed that the ventilation systems successfully controlled toluene and xylene vapors in workplace, air well below the recommended threshold limit value of Iran (44.49 and 97.73 ppm, respectively. It was also discovered that benzene concentration in workplace air was higher than its allowable concentrations. This could be from solvents impurities that require more investigations.

  18. Newly developed surface modification punches treated with alloying techniques reduce sticking during the manufacture of ibuprofen tablets.

    Science.gov (United States)

    Uchimoto, Takeaki; Iwao, Yasunori; Yamamoto, Tatsuya; Sawaguchi, Kazuo; Moriuchi, Toshiaki; Noguchi, Shuji; Itai, Shigeru

    2013-01-30

    Sticking is a serious problem during the manufacturing process of tablets. In order to prevent this, we used alloying techniques to prepare metal hardening (MH) and electron beam processing infinite product (EIP) punches with rougher asperity of surfaces than a hard chrome plated (HCr) punch. This study evaluated the anti-sticking properties of the MH and EIP punches compared to the HCr punch, using quantitative scraper force measurements and visual observation, for the manufacture of ibuprofen (Ibu) tablets. The anti-sticking property mechanism of the MH and EIP punches was also confirmed. The amount of Ibu adhering to the punch surface was 66% lower for the MH and EIP punches than for the HCr punch, suggesting a superior anti-sticking property of the MH and EIP punches. The scraper force of the HCr punch was 2.60-4.28 N, while that for the MH and EIP punches was 0.54-1.64 N and 0.42-1.33 N, respectively. The result of X-ray photoelectron spectroscopy suggested that the anti-sticking property of the EIP punch was attributed by the rough asperity as well as existence of low friction substance carbon fluoride on the punch surface. In conclusion, this study provides new evidence for the mechanisms behind the superior anti-sticking property of the MH and EIP punches. Copyright © 2013 Elsevier B.V. All rights reserved.

  19. Cost-effectiveness of preventive interventions to reduce alcohol consumption in Denmark.

    Directory of Open Access Journals (Sweden)

    Astrid Ledgaard Holm

    Full Text Available INTRODUCTION: Excessive alcohol consumption increases the risk of many diseases and injuries, and the Global Burden of Disease 2010 study estimated that 6% of the burden of disease in Denmark is due to alcohol consumption. Alcohol consumption thus places a considerable economic burden on society. METHODS: We analysed the cost-effectiveness of six interventions aimed at preventing alcohol abuse in the adult Danish population: 30% increased taxation, increased minimum legal drinking age, advertisement bans, limited hours of retail sales, and brief and longer individual interventions. Potential health effects were evaluated as changes in incidence, prevalence and mortality of alcohol-related diseases and injuries. Net costs were calculated as the sum of intervention costs and cost offsets related to treatment of alcohol-related outcomes, based on health care costs from Danish national registers. Cost-effectiveness was evaluated by calculating incremental cost-effectiveness ratios (ICERs for each intervention. We also created an intervention pathway to determine the optimal sequence of interventions and their combined effects. RESULTS: Three of the analysed interventions (advertising bans, limited hours of retail sales and taxation were cost-saving, and the remaining three interventions were all cost-effective. Net costs varied from € -17 million per year for advertisement ban to € 8 million for longer individual intervention. Effectiveness varied from 115 disability-adjusted life years (DALY per year for minimum legal drinking age to 2,900 DALY for advertisement ban. The total annual effect if all interventions were implemented would be 7,300 DALY, with a net cost of € -30 million. CONCLUSION: Our results show that interventions targeting the whole population were more effective than individual-focused interventions. A ban on alcohol advertising, limited hours of retail sale and increased taxation had the highest probability of being cost

  20. HUMAN RESPONDING ON RANDOM-INTERVAL SCHEDULES OF RESPONSE-COST PUNISHMENT: THE ROLE OF REDUCED REINFORCEMENT DENSITY

    OpenAIRE

    Pietras, Cynthia J; Brandt, Andrew E; Searcy, Gabriel D

    2010-01-01

    An experiment with adult humans investigated the effects of response-contingent money loss (response-cost punishment) on monetary-reinforced responding. A yoked-control procedure was used to separate the effects on responding of the response-cost contingency from the effects of reduced reinforcement density. Eight adults pressed buttons for money on a three-component multiple reinforcement schedule. During baseline, responding in all components produced money gains according to a random-inter...