WorldWideScience

Sample records for real life problems

  1. A Real-Life Case Study of Audit Interactions--Resolving Messy, Complex Problems

    Science.gov (United States)

    Beattie, Vivien; Fearnley, Stella; Hines, Tony

    2012-01-01

    Real-life accounting and auditing problems are often complex and messy, requiring the synthesis of technical knowledge in addition to the application of generic skills. To help students acquire the necessary skills to deal with these problems effectively, educators have called for the use of case-based methods. Cases based on real situations (such…

  2. A Simple Method for Solving Fully Intuitionistic Fuzzy Real Life Assignment Problem

    OpenAIRE

    Senthil Kumar, P.; Jahir Hussain, R.

    2016-01-01

    In solving real life assignment problem we often face the state of uncertainty as well as hesitation due to various uncontrollable factors. To deal with uncertainty and hesitation many authors have suggested the intuitionistic fuzzy representations for the data. So, in this paper, the authors consider the assignment problem having uncertainty and hesitation in cost/time/profit. They formulate the problem and utilize triangular intuitionistic fuzzy numbers (TIFNs) to deal with uncertainty and ...

  3. Bringing Reality into Calculus Classrooms: Mathematizing a Real-life Problem Simulated in a Virtual Environment

    Directory of Open Access Journals (Sweden)

    Olga V. Shipulina

    2013-01-01

    Full Text Available The study explores how students, who had completed the AP calculus course, mathematized the optimal navigation real-life problem simulated in the Second Life Virtual Environment. The particular research interest was to investigate whether/how students’ empirical activity in VE influences the way of their mathematizing.

  4. The Use of a Real Life Simulated Problem Based Learning Activity in a Corporate Environment

    Science.gov (United States)

    Laurent, Mark A.

    2013-01-01

    This narrative study examines using a real life simulated problem base learning activity during education of clinical staff, which is expected to design and develop clinically correct electronic charting systems. Expertise in healthcare does not readily transcend to the realm of manipulating software to collect patient data that is pertinent to…

  5. Do children do what they say? Responses to hypothetical and real-life social problems in children with mild intellectual disabilities and behaviour problems

    NARCIS (Netherlands)

    van Nieuwenhuijzen, M; Bijman, ER; Lamberix, ICW; Wijnroks, L; de Castro, BO; Vermeer, A; Matthys, W

    Background Most research on children's social problem-solving skills is based on responses to hypothetical vignettes. Just how these responses relate to actual behaviour in real-life social situations is, however, unclear, particularly for children with mild intellectual disabilities (MID). Method

  6. Do Children Do What They Say? Responses to Hypothetical and Real-Life Social Problems in Children with Mild Intellectual Disabilities and Behaviour Problems

    Science.gov (United States)

    van Nieuwenhuijzen, M.; Bijman, E. R.; Lamberix, I. C. W.; Wijnroks, L.; de Castro, B. Orobio; Vermeer, A.; Matthys, W.

    2005-01-01

    Abstract: Background Most research on children's social problem-solving skills is based on responses to hypothetical vignettes. Just how these responses relate to actual behaviour in real-life social situations is, however, unclear, particularly for children with mild intellectual disabilities (MID). Method: In the present study, the spontaneous…

  7. Solving real-life problems: future mobile technology sophistication

    International Nuclear Information System (INIS)

    Shafiq, F.; Ahsan, K.; Nadeem, A.

    2016-01-01

    Almost all the human being real life concerned domains are taking advantage of latest technologies for enhancing their process, procedures and operations. This integration of technological innovations provides ease of access, flexibility, transparency, reliability and speed for the concerned process and procedures. Rapid growth of ICT (Information and Communication Technology) and MT (Mobile Technology) provides opportunity to redesign and re-engineered the human routines life activities process and procedures. Technology integration and adoption in routine life activities may serves compensatory mechanism to assist the population in different manner such as monitoring older adults and children at homes, provides security assistance, monitoring and recording patients vital signs automatically, controlling and monitoring equipments and devices, providing assistance in shopping, banking and education as well. Disasters happened suddenly, destroy everything indiscriminately. Adoption and integration of latest technologies including ICT and MT can enhance the current disaster management process, procedures and operations. This research study focuses the impacts of latest and emerging technology trends in routine life activities and surrounds their potential strength to improve and enhance disaster management activities. MT is providing a promising platform for facilitating people to enhance their routine life activities. This research argue that integration and adoption of mobile computing in disaster management domain can enhance disaster management activities with promising minimizing error, quick information assembling, quick response based on technology manipulation and prioritizing action. (author)

  8. Solving Real-Life Problems: Future Mobile Technology Sophistication

    Directory of Open Access Journals (Sweden)

    FARHAN SHAFIQ

    2016-07-01

    Full Text Available Almost all the human being real life concerned domains are taking advantage of latest technologies for enhancing their process, procedures and operations. This integration of technological innovations provides ease of access, flexibility, transparency, reliability and speed for the concerned process and procedures. Rapid growth of ICT (Information and Communication Technology and MT (Mobile Technology provides opportunity to redesign and reengineered the human routines? life activities process and procedures. Technology integration and adoption in routine life activities may serves compensatory mechanism to assist the population in different manner such as monitoring older adults and children at homes, provides security assistance, monitoring and recording patients vital signs automatically, controlling and monitoring equipments and devices, providing assistance in shopping, banking and education as well. Disasters happened suddenly, destroy everything indiscriminately. Adoption and integration of latest technologies including ICT and MT can enhance the current disaster management process, procedures and operations. This research study focuses the impacts of latest and emerging technology trends in routine life activities and surrounds their potential strength to improve and enhance disaster management activities. MT is providing a promising platform for facilitating people to enhance their routine life activities. This research argue that integration and adoption of mobile computing in disaster management domain can enhance disaster management activities with promising minimizing error, quick information assembling, quick response based on technology manipulation and prioritizing action.

  9. Real-Life Research: Project Runway Makeover Model

    Science.gov (United States)

    Jaeger, Paige; Nesi, Olga M.

    2014-01-01

    Real-life research is incredibly varied. We research cars. We research lawn problems. We research child behavior problems, health issues, possible vacation destinations, and prices to stretch our budgets. No two scenarios are ever alike, and no two health issues should be assumed to be the same. That is reality, and that is a picture of what the…

  10. Generalized Artificial Life Structure for Time-dependent Problems

    Institute of Scientific and Technical Information of China (English)

    TSAU Minhe; KAO Weiwen; CHANG Albert

    2009-01-01

    In recent years, more attention has been paid on artificial life researches. Artificial life(AL) is a research on regulating gene parameters of digital organisms under complicated problematic environments through natural selections and evolutions to achieve the final emergence of intelligence. Most recent studies focused on solving certain real problems by artificial life methods, yet without much address on the AL life basic mechanism. The real problems are often very complicated, and the proposed methods sometimes seem too simple to handle those problems. This study proposed a new approach in AL research, named "generalized artificial life structure(GALS)", in which the traditional "gene bits" in genetic algorithms is first replaced by "gene parameters", which could appear anywhere in GALS. A modeling procedure is taken to normalize the input data, and AL "tissue" is innovated to make AL more complex. GALS is anticipated to contribute significantly to the fitness of AL evolution. The formation of"tissue" begins with some different AL basic cells, and then tissue is produced by the casual selections of one or several of these cells. As a result, the gene parameters, represented by "tissues", could become highly diversified. This diversification should have obvious effects on improving gene fitness. This study took the innovative method of GALS in a stock forecasting problem under a carefully designed manipulating platform. And the researching results verify that the GALS is successful in improving the gene evolution fitness.

  11. Communication patterns and satisfaction levels in three-dimensional versus real-life intimate relationships.

    Science.gov (United States)

    Gilbert, Richard L; Murphy, Nora A; Ávalos, M Clementina

    2011-10-01

    The present study compared communication patterns and satisfaction levels between three-dimensional (3D) and real-life intimate relationships using a sample of 71 participants who were concurrently involved in an intimate relationship within Second Life and a separate real-life romantic relationship. Participants indicated that the quality of their communication was significantly better in their Second-Life relationship and that they experienced higher levels of satisfaction with their virtual partners. The more positive or idealized view of the 3D relationships may have been due to higher levels of focused interaction and reduced stressors in the virtual world and the greater length, and associated problems, in participant's real-life relationships. In addition, the presence of a concurrent relationship within Second Life could have negatively affected participant's judgments of their real-life relationships. These data offer the first detailed assessment of communication patterns and satisfaction levels in intimate relationships across the real and 3D virtual realms as the number of users and romantic partners in immersive virtual environments continue to grow.

  12. PROBLEMS OF BUSINESS MANAGEMENT WITHIN A REAL ESTATE DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Dmitriy A. Bryksin

    2013-01-01

    Full Text Available This article describes problems of organization management within a real estate development, the analysis of this problems and the methods of its solution based on the Balanced Scorecard. In present unsteady conditions of business development, commercial activity faces a number of problems. The main types are: the problem of lack of funding, the problem of the growth of a company, the company’s management problem, the problem of business processes, and the problem of the decision-making. As a method to solve the problems is proposed an introduction of the balanced scorecard (BSC, which allows accurately feel the slightest changes in the company, deviation from the planned strategies and adjust the direction of the motion during the life of the company.

  13. Efficient and Flexible KNN Query Processing in Real-Life Road Networks

    DEFF Research Database (Denmark)

    Lu, Yang; Bui, Bin; Zhao, Jiakui

    2008-01-01

    are included into the RNG index, which enables the index to support both distance-based and time-based KNN queries and continuous KNN queries. Our work extends previous ones by taking into account more practical scenarios, such as complexities in real-life road networks and time-based KNN queries. Extensive......Along with the developments of mobile services, effectively modeling road networks and efficiently indexing and querying network constrained objects has become a challenging problem. In this paper, we first introduce a road network model which captures real-life road networks better than previous...

  14. Assessing the Value of Real-life Brands in Virtual Worlds

    DEFF Research Database (Denmark)

    Mattsson, Jan; Barnes, Stuart; Hartley, Nicole

    2015-01-01

    World. A key finding is the difficulty in creating emotional brand value in Second Life which has serious implications for the sustainability of current real-life brands in Virtual Worlds. The paper rounds off with conclusions and implications for future research and practice in this very new area.......Virtual Worlds are a significant new market environment for brand-building through experiential customer service interactions. Using value theory, this paper aims to assess the experiential brand value of real-life brands that have moved to the Virtual World of Second Life. A key premise...... is that current brand offerings in Virtual Worlds do not offer consumers adequate experiential value. The results demonstrate both the validity of an axiological approach to examining brand value, and highlight significant problems in consumer perceptions of the experiential value of brands within the Virtual...

  15. Shelf Life of Food Products: From Open Labeling to Real-Time Measurements.

    Science.gov (United States)

    Corradini, Maria G

    2018-03-25

    The labels currently used on food and beverage products only provide consumers with a rough guide to their expected shelf lives because they assume that a product only experiences a limited range of predefined handling and storage conditions. These static labels do not take into consideration conditions that might shorten a product's shelf life (such as temperature abuse), which can lead to problems associated with food safety and waste. Advances in shelf-life estimation have the potential to improve the safety, reliability, and sustainability of the food supply. Selection of appropriate kinetic models and data-analysis techniques is essential to predict shelf life, to account for variability in environmental conditions, and to allow real-time monitoring. Novel analytical tools to determine safety and quality attributes in situ coupled with modern tracking technologies and appropriate predictive tools have the potential to provide accurate estimations of the remaining shelf life of a food product in real time. This review summarizes the necessary steps to attain a transition from open labeling to real-time shelf-life measurements.

  16. A method for strategic technical life cycle management of real estates

    OpenAIRE

    Koskelo, Taina

    2005-01-01

    This research study focuses on the strategic technical life cycle management (TLCM) of real estate. In the early phases of the study it became clear that very often the performance of TLCM was not perceived as satisfactory: there were problems in the purchasing and provision of technical services, TLCM was not performed according to real estate specific needs and objective-setting for building characteristics did not serve cost-effective ownership. The study focuses on four research quest...

  17. Learning from Dealing with Real World Problems

    Science.gov (United States)

    Akcay, Hakan

    2017-01-01

    The purpose of this article is to provide an example of using real world issues as tools for science teaching and learning. Using real world issues provides students with experiences in learning in problem-based environments and encourages them to apply their content knowledge to solving current and local problems.

  18. Bringing real-world problems into the classroom

    NARCIS (Netherlands)

    Enserink, B.; De Haan, A.R.C.; Hermans, L.M.

    2012-01-01

    Real world problems are a challenge and a motivator for students to learn understanding and using the concepts of systems and actors. But using real world problems in the classroom is not without challenges and dilemmas. In the paper we explicitly address the issue of the need for quite intense

  19. Problem-Based Learning in the Life Science Classroom, K-12

    Science.gov (United States)

    McConnell, Tom; Parker, Joyce; Eberhardt, Janet

    2016-01-01

    "Problem-Based Learning in the Life Science Classroom, K-12" offers a great new way to ignite your creativity. Authors Tom McConnell, Joyce Parker, and Janet Eberhardt show you how to engage students with scenarios that represent real-world science in all its messy, thought-provoking glory. The scenarios prompt K-12 learners to immerse…

  20. Group Creativity Development by Solving Real-life Project in Engineering Education

    DEFF Research Database (Denmark)

    Zhou, Chunfang; Kolmos, Anette; Du, Xiangyun

    2011-01-01

    In recent years, problem and project based learning (PBL) has been employed by a growing number of educational institutions to foster creative engineers. Among the diverse pedagogical practices of PBL, there has been an emergence of real-life project for students. Based on literature of creativity...... along with the learning activities etc., which are necessary for group creativity development in engineering students....

  1. Real life working shift assignment problem

    Science.gov (United States)

    Sze, San-Nah; Kwek, Yeek-Ling; Tiong, Wei-King; Chiew, Kang-Leng

    2017-07-01

    This study concerns about the working shift assignment in an outlet of Supermarket X in Eastern Mall, Kuching. The working shift assignment needs to be solved at least once in every month. Current approval process of working shifts is too troublesome and time-consuming. Furthermore, the management staff cannot have an overview of manpower and working shift schedule. Thus, the aim of this study is to develop working shift assignment simulation and propose a working shift assignment solution. The main objective for this study is to fulfill manpower demand at minimum operation cost. Besides, the day off and meal break policy should be fulfilled accordingly. Demand based heuristic is proposed to assign working shift and the quality of the solution is evaluated by using the real data.

  2. Problems in real and functional analysis

    CERN Document Server

    Torchinsky, Alberto

    2015-01-01

    It is generally believed that solving problems is the most important part of the learning process in mathematics because it forces students to truly understand the definitions, comb through the theorems and proofs, and think at length about the mathematics. The purpose of this book is to complement the existing literature in introductory real and functional analysis at the graduate level with a variety of conceptual problems (1,457 in total), ranging from easily accessible to thought provoking, mixing the practical and the theoretical aspects of the subject. Problems are grouped into ten chapters covering the main topics usually taught in courses on real and functional analysis. Each of these chapters opens with a brief reader's guide stating the needed definitions and basic results in the area and closes with a short description of the problems. The Problem chapters are accompanied by Solution chapters, which include solutions to two-thirds of the problems. Students can expect the solutions to be written in ...

  3. The Real Problem (Humans) and Some Potentially Effective Alternatives and New Tools

    Energy Technology Data Exchange (ETDEWEB)

    Hanlon, Edward; Capece, John

    2011-01-07

    The presentation offers a wider perspective, where on the example of Everglades’ restoration efforts, the real problem – humans – is exposed. Some potentially effective alternatives and new tools are offered and discussed. Everglades’s problems are primarily caused to human activity, whether these are related to poor water quality, land use changes or cheap short-sighted fixes. Ground rules need to be set in order to have a real discussion and seek real solutions to such problems. The difference between facts and opinions is explained, so is the difference between interests and positions. These terms are often partly coinciding in human minds, thus causing further misunderstandings in pursuing real solutions. Some confounding factors in the Everglades restoration efforts are listed, with one of the main examples being the assignment of a monetary value to all factors. Some of these factors are priceless, but not being valued easily and properly (such as water). The proposed alternative to monetary value is assigning energy as the unit of measurement. The two main methods for such alternate approach are (1) Embodied energy (Emergy) and (2) Life Cycle Analysis. Agriculturally-based ecosystems services are different from natural ecosystems services. Pursuing agriculturally-based ecosystems services (such as e.g. water storage on farms, reducing nutrients in water, using flood-tolerant crops cultivars, etc.) can develop eco-services into agricultural operations and systems, addressing everyone’s interest and benefiting the society.

  4. Competence and Quality in Real-Life Decision Making.

    Science.gov (United States)

    Geisler, Martin; Allwood, Carl Martin

    2015-01-01

    What distinguishes a competent decision maker and how should the issue of decision quality be approached in a real-life context? These questions were explored in three studies. In Study 1, using a web-based questionnaire and targeting a community sample, we investigated the relationships between objective and subjective indicators of real-life decision-making success. In Study 2 and 3, targeting two different samples of professionals, we explored if the prevalent cognitively oriented definition of decision-making competence could be beneficially expanded by adding aspects of competence in terms of social skills and time-approach. The predictive power for each of these three aspects of decision-making competence was explored for different indicators of real-life decision-making success. Overall, our results suggest that research on decision-making competence would benefit by expanding the definition of competence, by including decision-related abilities in terms of social skills and time-approach. Finally, the results also indicate that individual differences in real-life decision-making success profitably can be approached and measured by different criteria.

  5. Competence and Quality in Real-Life Decision Making

    Science.gov (United States)

    2015-01-01

    What distinguishes a competent decision maker and how should the issue of decision quality be approached in a real-life context? These questions were explored in three studies. In Study 1, using a web-based questionnaire and targeting a community sample, we investigated the relationships between objective and subjective indicators of real-life decision-making success. In Study 2 and 3, targeting two different samples of professionals, we explored if the prevalent cognitively oriented definition of decision-making competence could be beneficially expanded by adding aspects of competence in terms of social skills and time-approach. The predictive power for each of these three aspects of decision-making competence was explored for different indicators of real-life decision-making success. Overall, our results suggest that research on decision-making competence would benefit by expanding the definition of competence, by including decision-related abilities in terms of social skills and time-approach. Finally, the results also indicate that individual differences in real-life decision-making success profitably can be approached and measured by different criteria. PMID:26545239

  6. Some "Real" Problems of "Virtual" Organisation.

    Science.gov (United States)

    Hughes, John A.; O'Brien, Jon; Randall, Dave; Rouncefield, Mark; Tolmie, Peter

    2001-01-01

    An ethnographic study of organizational change in a bank considered issues surrounding virtual teamwork in virtual organizations. Problems in communication, management control, and approach to customer service were found. An underlying cause is that "virtual" work involves "real" customers, workers, and problems. (Contains 36 references.) (SK)

  7. On-Board Real-Time Optimization Control for Turbo-Fan Engine Life Extending

    Science.gov (United States)

    Zheng, Qiangang; Zhang, Haibo; Miao, Lizhen; Sun, Fengyong

    2017-11-01

    A real-time optimization control method is proposed to extend turbo-fan engine service life. This real-time optimization control is based on an on-board engine mode, which is devised by a MRR-LSSVR (multi-input multi-output recursive reduced least squares support vector regression method). To solve the optimization problem, a FSQP (feasible sequential quadratic programming) algorithm is utilized. The thermal mechanical fatigue is taken into account during the optimization process. Furthermore, to describe the engine life decaying, a thermal mechanical fatigue model of engine acceleration process is established. The optimization objective function not only contains the sub-item which can get fast response of the engine, but also concludes the sub-item of the total mechanical strain range which has positive relationship to engine fatigue life. Finally, the simulations of the conventional optimization control which just consider engine acceleration performance or the proposed optimization method have been conducted. The simulations demonstrate that the time of the two control methods from idle to 99.5 % of the maximum power are equal. However, the engine life using the proposed optimization method could be surprisingly increased by 36.17 % compared with that using conventional optimization control.

  8. Gamer Girls, Gold Farmers, and Activism "In Real Life"

    Science.gov (United States)

    Musgrave, Megan L.

    2016-01-01

    This essay analyzes the graphic novel "In Real Life" as an example of Cory Doctorow and Jen Wang's intention to raise young people's awareness about gender and economic disparities within the gaming industry. Broadly, "In Real Life" combats the pervasive cultural anxiety that Jane McGonigal challenges in her book "Reality…

  9. Age related differences of executive functioning problems in everyday life of children and adolescents in the autism spectrum

    NARCIS (Netherlands)

    van den Bergh, S.F.W.M.; Scheeren, A.M.; Begeer, S.; Koot, H.M.; Geurts, H.M.

    2014-01-01

    Numerous studies investigated executive functioning (EF) problems in people with autism spectrum disorders (ASD) using laboratory EF tasks. As laboratory task performances often differ from real life observations, the current study focused on EF in everyday life of 118 children and adolescents with

  10. Competence and Quality in Real-Life Decision Making

    OpenAIRE

    Geisler, Martin; Allwood, Carl Martin

    2015-01-01

    What distinguishes a competent decision maker and how should the issue of decision quality be approached in a real-life context? These questions were explored in three studies. In Study 1, using a web-based questionnaire and targeting a community sample, we investigated the relationships between objective and subjective indicators of real-life decision-making success. In Study 2 and 3, targeting two different samples of professionals, we explored if the prevalent cognitively oriented definiti...

  11. An adaptation framework for turning real life events into games

    DEFF Research Database (Denmark)

    Therkildsen, Sacha Kjærhus; Bunkenborg, Nanna Cassøe; Larsen, Lasse Juel

    2017-01-01

    Many games are inspired by real life events. The presented adaptation framework is based on the design of a board game with a companion app that addresses the Syrian refugee crisis. The aim of the game is to allow players to simulate the experience of being a Syrian refugee traveling through Europe....... We applied an agile development method and participatory design to achieve our ambition. In conclusion we found that turning real life events into board games can be advanced by the following game design adaptation framework, which balances four interrelated layers: (1) real life events (game fiction...

  12. Emotional and Physiological Desensitization to Real-Life and Movie Violence

    Science.gov (United States)

    Mrug, Sylvie; Madan, Anjana; Cook, Edwin W.; Wright, Rex A.

    2014-01-01

    Youth are exposed to large amounts of violence in real life and media, which may lead to desensitization. Given evidence of curvilinear associations between exposure to violence and emotional distress, we examined linear and curvilinear associations of exposure to real-life and movie violence with PTSD symptoms, empathy, and physiological arousal, as well emotional and physiological reactivity to movie violence. College students (N=209; mean age=18.74) reported on their exposure to real-life and televised violence, PTSD symptoms, and empathy. Then, students were randomly assigned to view a series of violent or nonviolent high-action movie scenes, providing ratings of emotional distress after each clip. Blood pressure was measured at rest and during video viewing. Results showed that with increasing exposure to real-life violence, youth reported more PTSD symptoms and greater identification with fictional characters. Cognitive and emotional empathy increased from low to medium levels of exposure to violence, but declined at higher levels. For males, exposure to higher levels of real-life violence was associated with diminishing (vs. increasing) emotional distress when viewing violent videos. Exposure to televised violence was generally unrelated to emotional functioning. However, those with medium levels of exposure to TV/movie violence experienced lower elevations of blood pressure when viewing violent videos compared to those with low exposure, and those with higher levels of exposure evidenced rapid increase in blood pressure that quickly declined over time. The results point to diminished empathy and reduced emotional reactivity to violence as key aspects of desensitization to real-life violence, and more limited evidence of physiological desensitization to movie violence among those exposed to high levels of televised violence. PMID:25326900

  13. Real-Life Stories About Addiction Struggles | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... on. Feature: Preventing Drug Abuse and Addiction Real-Life Stories About Addiction Struggles Past Issues / Fall 2011 ... TO PLAY THE VIDEO NIHSeniorHealth Videos Offer Real-Life Stories About Addiction Struggles—and Much More Many ...

  14. Disruption Management for the Real-Time Home Caregiver Scheduling and Routing Problem

    Directory of Open Access Journals (Sweden)

    Biao Yuan

    2017-11-01

    Full Text Available The aggravating trend of the aging population, the miniaturization of the family structure, and the increase of families with empty nesters greatly affect the sustainable development of the national economy and social old-age security system of China. The emergence of home health care or home care (HHC/HC service mode provides an alternative for elderly care. How to develop and apply this new mobile service mode is crucial for the government. Therefore, the pertinent optimization problems regarding HHC/HC have constantly attracted the attention of researchers. Unexpected events, such as new requests of customers, cancellations of customers’ services, and changes of customers’ time windows, may occur during the process of executing an a priori visiting plan. These events may sometimes make the original plan non-optimal or even infeasible. To cope with this situation, we introduce disruption management to the real-time home caregiver scheduling and routing problem. The deviation measurements on customers, caregivers, and companies are first defined. A mathematical model that minimizes the weighted sum of deviation measurements is then constructed. Next, a tabu search (TS heuristic is developed to efficiently solve the problem, and a cost recorded mechanism is used to strengthen the performance. Finally, by performing computational experiments on three real-life instances, the effectiveness of the TS heuristic is tested, and the advantages of disruption management are analyzed.

  15. Solving math and science problems in the real world with a computational mind

    Directory of Open Access Journals (Sweden)

    Juan Carlos Olabe

    2014-07-01

    Full Text Available This article presents a new paradigm for the study of Math and Sciences curriculum during primary and secondary education. A workshop for Education undergraduates at four different campuses (n=242 was designed to introduce participants to the new paradigm. In order to make a qualitative analysis of the current school methodologies in mathematics, participants were introduced to a taxonomic tool for the description of K-12 Math problems. The tool allows the identification, decomposition and description of Type-A problems, the characteristic ones in the traditional curriculum, and of Type-B problems in the new paradigm. The workshops culminated with a set of surveys where participants were asked to assess both the current and the new proposed paradigms. The surveys in this study revealed that according to the majority of participants: (i The K-12 Mathematics curricula are designed to teach students exclusively the resolution of Type-A problems; (ii real life Math problems respond to a paradigm of Type-B problems; and (iii the current Math curriculum should be modified to include this new paradigm.

  16. Mathematics and engineering in real life through mathematical competitions

    Science.gov (United States)

    More, M.

    2018-02-01

    We bring out an experience of organizing mathematical competitions that can be used as a medium to motivate the student and teacher minds in new directions of thinking. This can contribute to fostering research, innovation and provide a hands-on experience of mathematical concepts with the real world. Mathematical competitions can be used to build curiosity and give an understanding of mathematical applications in real life. Participation in the competition has been classified under four broad categories. Student can showcase their findings in various forms of expression like model, poster, soft presentation, animation, live performance, art and poetry. The basic focus of the competition is on using open source computation tools and modern technology, to emphasize the relationship of mathematical concepts with engineering applications in real life.

  17. The effects of stating problems in bilingual students' first and second languages on solving mathematical word problems.

    Science.gov (United States)

    Bernardo, Allan B I; Calleja, Marissa O

    2005-03-01

    Researchers have suggested that among bilinguals, solving word problems in mathematics is influenced by linguistic factors (K. Durkin & B. Shire, 1991; L. Verschaffel, B. Greer, & E. De Corte, 2000). Others have suggested that students exhibit a strong tendency to exclude real-world constraints in solving mathematics word problems (L. Verschaffel, E. De Corte, & S. Lasure, 1994). In the present study, the authors explored the effects of stating word problems in either Filipino or English on how Filipino-English bilingual students solved word problems in which the solution required the application of real-world knowledge. The authors asked bilingual students to solve word problems in either their first or second language. For some of the word problems, real-life constraints prevented straightforward application of mathematical procedures. The authors analyzed the students' solutions to determine whether the language of the word problems affected the tendency to apply real-life constraints in the solution. Results showed that the bilingual students (a) rarely considered real-life constraints in their solutions, (b) were more successful in understanding and solving word problems that were stated in their first language, and (c) were more likely to experience failure in finding a solution to problems stated in their second language. The results are discussed in terms of the relationship between linguistic and mathematical problem-solving processes among bilinguals.

  18. Real-Life Efficacy, Immunogenicity and Safety of Biosimilar Infliximab.

    Science.gov (United States)

    Vegh, Zsuzsanna; Kurti, Zsuzsanna; Lakatos, Peter L

    2017-01-01

    Recently, the use of biosimilar infliximab (IFX) in the treatment of inflammatory bowel diseases has become widespread in some European and non-European countries. Data on the efficacy, safety and immunogenicity from real-life cohorts are accumulating. The first reports showed similar outcomes in the induction and maintenance of remission, mucosal healing, safety and immunogenicity profile to the originator IFX. In the present review, we aimed to summarize the existing knowledge on the efficacy, safety and immunogenicity profile of biosimilar IFX reported from real-life cohorts. © 2017 S. Karger AG, Basel.

  19. Metaheuristics progress as real problem solvers

    CERN Document Server

    Nonobe, Koji; Yagiura, Mutsunori

    2005-01-01

    Metaheuristics: Progress as Real Problem Solvers is a peer-reviewed volume of eighteen current, cutting-edge papers by leading researchers in the field. Included are an invited paper by F. Glover and G. Kochenberger, which discusses the concept of Metaheuristic agent processes, and a tutorial paper by M.G.C. Resende and C.C. Ribeiro discussing GRASP with path-relinking. Other papers discuss problem-solving approaches to timetabling, automated planograms, elevators, space allocation, shift design, cutting stock, flexible shop scheduling, colorectal cancer and cartography. A final group of methodology papers clarify various aspects of Metaheuristics from the computational view point.

  20. Virtual Worlds: Relationship between Real Life and Experience in Second Life

    Science.gov (United States)

    Anstadt, Scott P.; Bradley, Shannon; Burnette, Ashley; Medley, Lesley L.

    2013-01-01

    Due to the unique applications of virtual reality in many modern contexts, Second Life (SL) offers inimitable opportunities for research and exploration and experiential learning as part of a distance learning curriculum assignment. A review of current research regarding SL examined real world social influences in online interactions and what the…

  1. Knowledge Management and Problem Solving in Real Time: The Role of Swarm Intelligence

    Directory of Open Access Journals (Sweden)

    Chris W Callaghan

    2016-06-01

    Full Text Available Knowledge management research applied to the development of real-time research capability, or capability to solve societal problems in hours and days instead of years and decades, is perhaps increasingly important, given persistent global problems such as the Zika virus and rapidly developing antibiotic resistance. Drawing on swarm intelligence theory, this paper presents an approach to real-time research problem-solving in the form of a framework for understanding the complexity of real-time research and the challenges associated with maximizing collaboration. The objective of this research is to make explicit certain theoretical, methodological, and practical implications deriving from new literature on emerging technologies and new forms of problem solving and to offer a model of real-time problem solving based on a synthesis of the literature. Drawing from ant colony, bee colony, and particle swarm optimization, as well as other population-based metaheuristics, swarm intelligence principles are derived in support of improved effectiveness and efficiency for multidisciplinary human swarm problem-solving. This synthesis seeks to offer useful insights into the research process, by offering a perspective of what maximized collaboration, as a system, implies for real-time problem solving.

  2. Nuclear energy; real problems of the long term development

    International Nuclear Information System (INIS)

    Knapp, V.

    1996-01-01

    Whilst general public accepts the operation of western designed nuclear power stations as safe, waste management and decommission still figure as open problems, although such views are not in agreement with technical and economic status of these operations. A concern with imagined problems can have the effect of neglecting the real ones. In considering the long term development of nuclear energy the real problems can be associated with the wide use of plutonium and multiplication of national reprocessing and enrichment installations. Nuclear proliferation safety could be retained and developed through establishment of international nuclear fuel centres. Their operation would be particularly beneficial for small or medium nuclear countries. Several arguments are given why it is not premature to initiate a study which would identify and analyze the problems of establishing an international nuclear fuel centre. Central Europe could be a region which could be served by one of such nuclear fuel centres. (author)

  3. Implementation Process of 5S for a Company in Real Life - Problems, Solutions, Successes

    Science.gov (United States)

    Czifra, György

    2017-09-01

    Developed in Japan, 5S is a system of organizing workplace for efficiency, effectiveness and safety. Is 5s important? The answer is: "YES", because the implementation is about empowering employees to control their work area and create an environment where they want to work every day. It is a program that only works with grass roots level engagement. With commitment to safety, we are equally committed to 5S to ensure a safe place to work. It enabled us to indicate where waste was occurring and thus improve the work area sustainably. We recognized real problems, found solutions and ultimately we were successful in our endeavors. Throughout different companies, various words of similar meaning are used. No matter what specific words are used to identify the steps in 5S, the purpose remains the same: create a clean, organized and efficient work environment.

  4. Implementation Process of 5S for a Company in Real Life - Problems, Solutions, Successes

    Directory of Open Access Journals (Sweden)

    Czifra György

    2017-09-01

    Full Text Available Developed in Japan, 5S is a system of organizing workplace for efficiency, effectiveness and safety. Is 5s important? The answer is: “YES”, because the implementation is about empowering employees to control their work area and create an environment where they want to work every day. It is a program that only works with grass roots level engagement. With commitment to safety, we are equally committed to 5S to ensure a safe place to work. It enabled us to indicate where waste was occurring and thus improve the work area sustainably. We recognized real problems, found solutions and ultimately we were successful in our endeavors. Throughout different companies, various words of similar meaning are used. No matter what specific words are used to identify the steps in 5S, the purpose remains the same: create a clean, organized and efficient work environment.

  5. Transition to life--a sendoff to the real world for graduating medical students.

    Science.gov (United States)

    Coates, Wendy C; Spector, Tahlia S; Uijtdehaage, Sebastian

    2012-01-01

    Graduating medical students will enter the workforce, often for the first time. Many have spent the past 20 years as students, receiving financial support from parents, and have not managed real-life issues such as financial planning, real estate, balancing well-being with employment, and integrating into a new community with stressful working conditions. To address a perceived need, we designed an intervention to introduce graduating medical students to financial planning, real estate choices, physician wellness during relocation/internship, and traits of efficient interns. The objectives of this study are to (a) assess baseline experience, knowledge, and comfort of seniors about "real-life" experiences, and (b) assess the efficacy of a 4-hr educational intervention on perceptions of understanding financial planning, real estate choices, intern preparedness, and physician wellness. Acute Care College seniors (classes of 2009 and 2010) attended the intervention after match day and completed a survey to gather demographic data and assess preexisting knowledge and a postintervention survey (1-7 Likert scale). Forty-nine students (45% male; M age = 25.5 years) participated. Prior experiences: 43% no break in education, 51% no full-time job, 38% never signed a rental lease and 94% had not purchased real estate, 90% did not have (or were not aware of having) disability insurance, and 82% had educational debt exceeding $50,000. Following the workshop, students felt more confident in their understanding of life skills topics (real estate, 83%; financial planning, 94%; well-being, 86%). Our workshop assisted in preparing for life after medical school for 98% of the participants. Graduating medical students can gain knowledge about real-life responsibilities and confidence during an educational session prior to starting residency.

  6. Endangered Species: Real Life in Two Dimensions

    Science.gov (United States)

    Henderson, Lynette K.

    2012-01-01

    The focus of "Endangered Species: Real Life in Two Dimensions" is to create awareness about a critical environmental issue. There is a special urgency to this project because large numbers of animal species are currently endangered or on the brink of extinction. In addition to being enlightened about this important topic through research, students…

  7. Towards a conceptual framework for identifying student difficulties with solving Real-World Problems in Physics

    DEFF Research Database (Denmark)

    Niss, Martin

    2012-01-01

    This paper develops a conceptual framework for identifying the challenges and obstacles university students encounter when solving real-world problems involving Physics. The framework is based on viewing problem solving as a modelling process. In order to solve a real-world problem, the problem...... solver has to go through the steps and do the tasks of such a process. The paper presents a theoretical analysis of what it takes to solve three real-world problems, demonstrating how the framework presented captures the essential aspects of solving them. Moreover, it is argued that three steps critical...... for real-world problem solving – initial analysis of the problem situation, choice of relevant physical theory (the so-called paradigmatic choice) and mathematization – are not covered by existing models of problem solving in Physics. Finally, the existing research on student difficulties with problem...

  8. Non-Stop Lab Week: A Real Laboratory Experience for Life Sciences Postgraduate Courses

    Science.gov (United States)

    Freitas, Maria João; Silva, Joana Vieira; Korrodi-Gregório, Luís; Fardilha, Margarida

    2016-01-01

    At the Portuguese universities, practical classes of life sciences are usually professor-centered 2-hour classes. This approach results in students underprepared for a real work environment in a research/clinical laboratory. To provide students with a real-life laboratory environment, the Non-Stop Lab Week (NSLW) was created in the Molecular…

  9. Idiopathic pulmonary fibrosis: from clinical trials to real-life experiences

    Directory of Open Access Journals (Sweden)

    Sergio Harari

    2015-09-01

    Full Text Available Randomised controlled clinical trials are fundamental in medicine to develop new effective drugs and new therapeutic regimens and are the strength of evidence-based medicine. These studies allow us to avoid the repetition of misleading experiences that have been reported in the past, where drugs or associations were utilised without compelling evidence and ultimately proven to be ineffective. In recent years, randomised clinical trials have been conducted and concluded for many rare diseases, including idiopathic pulmonary fibrosis. However, clinical trials do not always reflect the real-life scenario. Patients selected for clinical trials present fewer comorbidities, they fall between certain age limits, and the severity of their disease is defined; therefore, they do not always reflect the whole of the population affected by a specific disease. These are the reasons why we also need data that mirror real-life experience. The limitations that these kind of studies present are always several and the studies should be interpreted with caution, although they can fill the important gap between efficacy and effectiveness. In this article, we will review the existing clinical data on real-life treatment of idiopathic pulmonary fibrosis.

  10. Social Anxiety in Online and Real-Life Interaction and Their Associated Factors

    OpenAIRE

    Yen, Ju-Yu; Yen, Cheng-Fang; Chen, Cheng-Sheng; Wang, Peng-Wei; Chang, Yi-Hsin; Ko, Chih-Hung

    2012-01-01

    Social anxiety was compared between online and real-life interaction in a sample of 2,348 college students. Severity of social anxiety in both real-life and online interaction was tested for associations with depression, Internet addiction, Internet activity type (gaming versus chatting), and scores on Behavioral Inhibition System (BIS)/Behavioral Activation System (BAS) scales. The results showed that social anxiety was lower when interacting online than when interacting offline. Depression,...

  11. Research on Life Science and Life Support Engineering Problems of Manned Deep Space Exploration Mission

    Science.gov (United States)

    Qi, Bin; Guo, Linli; Zhang, Zhixian

    2016-07-01

    Space life science and life support engineering are prominent problems in manned deep space exploration mission. Some typical problems are discussed in this paper, including long-term life support problem, physiological effect and defense of varying extraterrestrial environment. The causes of these problems are developed for these problems. To solve these problems, research on space life science and space medical-engineering should be conducted. In the aspect of space life science, the study of space gravity biology should focus on character of physiological effect in long term zero gravity, co-regulation of physiological systems, impact on stem cells in space, etc. The study of space radiation biology should focus on target effect and non-target effect of radiation, carcinogenicity of radiation, spread of radiation damage in life system, etc. The study of basic biology of space life support system should focus on theoretical basis and simulating mode of constructing the life support system, filtration and combination of species, regulation and optimization method of life support system, etc. In the aspect of space medical-engineering, the study of bio-regenerative life support technology should focus on plants cultivation technology, animal-protein production technology, waste treatment technology, etc. The study of varying gravity defense technology should focus on biological and medical measures to defend varying gravity effect, generation and evaluation of artificial gravity, etc. The study of extraterrestrial environment defense technology should focus on risk evaluation of radiation, monitoring and defending of radiation, compound prevention and removal technology of dust, etc. At last, a case of manned lunar base is analyzed, in which the effective schemes of life support system, defense of varying gravity, defense of extraterrestrial environment are advanced respectively. The points in this paper can be used as references for intensive study on key

  12. Virtually numbed: immersive video gaming alters real-life experience.

    Science.gov (United States)

    Weger, Ulrich W; Loughnan, Stephen

    2014-04-01

    As actors in a highly mechanized environment, we are citizens of a world populated not only by fellow humans, but also by virtual characters (avatars). Does immersive video gaming, during which the player takes on the mantle of an avatar, prompt people to adopt the coldness and rigidity associated with robotic behavior and desensitize them to real-life experience? In one study, we correlated participants' reported video-gaming behavior with their emotional rigidity (as indicated by the number of paperclips that they removed from ice-cold water). In a second experiment, we manipulated immersive and nonimmersive gaming behavior and then likewise measured the extent of the participants' emotional rigidity. Both studies yielded reliable impacts, and thus suggest that immersion into a robotic viewpoint desensitizes people to real-life experiences in oneself and others.

  13. Life satisfaction and mental health problems (18 to 35 years).

    Science.gov (United States)

    Fergusson, D M; McLeod, G F H; Horwood, L J; Swain, N R; Chapple, S; Poulton, R

    2015-08-01

    Previous research has found that mental health is strongly associated with life satisfaction. In this study we examine associations between mental health problems and life satisfaction in a birth cohort studied from 18 to 35 years. Data were gathered during the Christchurch Health and Development Study, which is a longitudinal study of a birth cohort of 1265 children, born in Christchurch, New Zealand, in 1977. Assessments of psychiatric disorder (major depression, anxiety disorder, suicidality, alcohol dependence and illicit substance dependence) using DSM diagnostic criteria and life satisfaction were obtained at 18, 21, 25, 30 and 35 years. Significant associations (p life satisfaction and the psychiatric disorders major depression, anxiety disorder, suicidality, alcohol dependence and substance dependence. After adjustment for non-observed sources of confounding by fixed effects, statistically significant associations (p life satisfaction and major depression, anxiety disorder, suicidality and substance dependence. Overall, those reporting three or more mental health disorders had mean life satisfaction scores that were nearly 0.60 standard deviations below those without mental health problems. A structural equation model examined the direction of causation between life satisfaction and mental health problems. Statistically significant (p life satisfaction and mental health problems. After adjustment for confounding, robust and reciprocal associations were found between mental health problems and life satisfaction. Overall, this study showed evidence that life satisfaction influences mental disorder, and that mental disorder influences life satisfaction.

  14. Problems and Perspectives of Life Management Theory

    OpenAIRE

    Hirata, Michinori

    2001-01-01

    This paper examines the problems of life management theory and shows the directions of researches in this field. I examine the directions of research in home management theory, which is antecedents of life management theory. There are three directions of research in home management theory. The first direction is to make clear the problems of people's family lives in terms of time use, money expenditure, family relations and so on. The second direction is to examine the home management itself....

  15. Late-life and life history predictors of older adults' high-risk alcohol consumption and drinking problems.

    Science.gov (United States)

    Moos, Rudolf H; Schutte, Kathleen K; Brennan, Penny L; Moos, Bernice S

    2010-04-01

    This prospective, longitudinal study focused on late-life and life history predictors of high-risk alcohol consumption and drinking problems during a 20-year interval as adults matured from age 55-65 to 75-85. A sample of older community residents (N=719) who had consumed alcohol in the past year or shortly before was surveyed at baseline and 10 and 20 years later. At each contact point, participants completed an inventory that assessed their alcohol consumption, drinking problems, and personal and life context factors. Participants also provided information about their life history of drinking and help-seeking. Older adults who, at baseline, had more friends who approved of drinking, relied on substances for tension reduction, and had more financial resources were more likely to engage in high-risk alcohol consumption and to incur drinking problems at 10- and 20-year follow-ups. With respect to life history factors, drinking problems by age 50 were associated with a higher likelihood of late-life high-risk alcohol consumption and drinking problems; having tried to cut down on drinking and participation in Alcoholics Anonymous were associated with a lower likelihood of high-risk consumption and problems. Specific late-life and life history factors can identify older adults likely to engage in excessive alcohol consumption 10 and 20 years later. Targeted screening that considers current alcohol consumption and life context, and history of drinking problems and help-seeking, could help identify older adults at higher risk for excessive or problematic drinking. Published by Elsevier Ireland Ltd.

  16. Improvisation of Real-Life Scenarios through Intercultural Competence

    Science.gov (United States)

    Okten, Celile Eren; Griffin, Banu Ozer

    2016-01-01

    This paper describes tasks based on real-life scenarios, which triggered reflective thinking, verbalization, and writing, leading to the creation of natural dialogues rather than artificial, dull monologues. One of the main aims of this approach is to engage students in a dynamic process of both learning about multicultural participants and…

  17. From real life to real life

    DEFF Research Database (Denmark)

    Svalgaard, Lotte

    2017-01-01

    In Action Learning programmes, it is held central to work on real business challenges (task) while learning about team and self (process); staying mindful aware of the process is referred to in this paper as ‘double awareness’, and emphasises noticing and acting on process cues while working on t...

  18. Virtual Worlds: Relationship Between Real Life and Experience in Second Life

    Directory of Open Access Journals (Sweden)

    Scott P. Anstadt

    2013-09-01

    Full Text Available Due to the unique applications of virtual reality in many modern contexts, Second Life (SL offers inimitable opportunities for research and exploration and experiential learning as part of a distance learning curriculum assignment. A review of current research regarding SL examined real world social influences in online interactions and what the effects on users may be. This aids students in understanding the social constructionist perceptions and worldview of those persons they may serve in social services. This suggests the importance of developing an understanding of the relationship between users’ real life (RL and their SL. Some research has begun to reveal the effectiveness of telecommunication and computer simulation with certain clients in the fields of mental health and social work, yet there is a lack of sufficient research done within the context of virtual worlds. The current study surveyed users of several educationally and health focused SIMS (simulations as to what motivates their SL and RL interactions. The data explores associations between users’ RL and their SL in several areas,potentially addressing the future role of educating social work students regarding research methodology in online virtual reality interactions. Implications for social work are discussed including engaging clients using incentives for social participation built into the SL milieu.

  19. Children's Eyewitness Memory for Multiple Real-Life Events

    Science.gov (United States)

    Odegard, Timothy N.; Cooper, Crystal M.; Lampinen, James M.; Reyna, Valerie F.; Brainerd, Charles J.

    2009-01-01

    The present research examined the influence of prior knowledge on children's free recall, cued recall, recognition memory, and source memory judgments for a series of similar real-life events. Forty children (5-12 years old) attended 4 thematic birthday parties and were later interviewed about the events that transpired during the parties using…

  20. Rendezvous with IQ: Metacognition in Real-Life Situations

    Science.gov (United States)

    Al-Hilawani, Yasser A.

    2018-01-01

    The purpose of this study was to examine the relationship between metacognition as measured in real-life situations and IQ scores as reflected by performance on the Raven Standard Progressive Matrices Scale. It is also intended in this study to report on whether or not there were significant differences in performance on the metacognitive…

  1. Modified Approach for Optimization of Real Life Transportation Problem in Neutrosophic Environment

    Directory of Open Access Journals (Sweden)

    Akanksha Singh

    2017-01-01

    Full Text Available To the best of our knowledge, there is only one approach for solving neutrosophic cost minimization transportation problems. Since neutrosophic transportation problems are a new area of research, other researchers may be attracted to extend this approach for solving other types of neutrosophic transportation problems like neutrosophic solid transportation problems, neutrosophic time minimization transportation problems, neutrosophic transshipment problems, and so on. However, after a deep study of the existing approach, it is noticed that a mathematical incorrect assumption has been used in these existing approaches; therefore there is a need to modify these existing approaches. Keeping the same in mind, in this paper, the existing approach is modified. Furthermore, the exact results of some existing transportation problems are obtained by the modified approach.

  2. Cognitive constraints on high school students' representations of real environmental problems

    Science.gov (United States)

    Barnes, Ervin Kenneth

    One class of juniors and seniors was studied through one semester in the investigation of how students think about, learn from, and solve real environmental problems. The intention was to listen to student voices while researching the features of their representations of these problems, the beliefs they held (tenets), the cognitive processes they employed, and the principles of science, ecology, problem solving, and ethics they held as tenets. The focus was upon two self-selected groups as they perceived, engaged, analyzed, and proposed solutions for problems. Analysis of the student representations involved interpretation of the features to include both the perspective tenets and the envisioning processes. These processes included the intentive and attentive constraints as tenet acquisition and volitive and agential constraints as tenet affirmation. The perspective tenets included a variety of conceptual (basic science, ecological, ethical, and problem-solving) constraints as well as ontological, epistemological, and other cultural (role, status, power, and community) constraints. The perspective tenets were interpreted thematically including the ways populations of people cause and care about environmental problems, the magnitude of environmental problems and the science involved, the expectations and limitations students perceive for themselves, and the importance of community awareness and cooperation to addressing these problems. Some of these tenets were interpreted to be principles in that they were rules that were accepted by some people as true. The perspective tenets, along with the envisioning processes, were perceived to be the constraints that determined the environmental problems and limited the solution possibilities. The students thought about environmental problems in mature and principled ways using a repertoire of cognitive processes. They learned from them as they acquired and affirmed tenets. They solved them through personal choices and

  3. Clinical and economic impact of etanercept in real-life

    DEFF Research Database (Denmark)

    Larsen, Christian Grønhøj; Andersen, Peter Hundevadt; Lorentzen, Henrik

    2013-01-01

    BACKGROUND: Real-life data on the therapeutic effectiveness and costs of etanercept are scarce. Objectives: To assess the clinical and economic impact of etanercept in patients with psoriasis in Denmark and Norway. MATERIAL & METHODS: This prospective, non-interventional study in a private...

  4. Teaching problem solving using non-routine tasks

    Science.gov (United States)

    Chong, Maureen Siew Fang; Shahrill, Masitah; Putri, Ratu Ilma Indra; Zulkardi

    2018-04-01

    Non-routine problems are related to real-life context and require some realistic considerations and real-world knowledge in order to resolve them. This study examines several activity tasks incorporated with non-routine problems through the use of an emerging mathematics framework, at two junior colleges in Brunei Darussalam. The three sampled teachers in this study assisted in selecting the topics and the lesson plan designs. They also recommended the development of the four activity tasks: incorporating the use of technology; simulation of a reality television show; designing real-life sized car park spaces for the school; and a classroom activity to design a real-life sized dustpan. Data collected from all four of the activity tasks were analyzed based on the students' group work. The findings revealed that the most effective activity task in teaching problem solving was to design a real-life sized car park. This was because the use of real data gave students the opportunity to explore, gather information and give or receive feedback on the effect of their reasons and proposed solutions. The second most effective activity task was incorporating the use of technology as it enhanced the students' understanding of the concepts learnt in the classroom. This was followed by the classroom activity that used real data as it allowed students to work and assess the results mathematically. The simulation of a television show was found to be the least effective since it was viewed as not sufficiently challenging to the students.

  5. Using Video Prompting to Teach Mathematical Problem Solving of Real-World Video-Simulation Problems

    Science.gov (United States)

    Saunders, Alicia F.; Spooner, Fred; Ley Davis, Luann

    2018-01-01

    Mathematical problem solving is necessary in many facets of everyday life, yet little research exists on how to teach students with more severe disabilities higher order mathematics like problem solving. Using a multiple probe across participants design, three middle school students with moderate intellectual disability (ID) were taught to solve…

  6. Electrochemical dehalogenisation of chlorinated aromatics - from model substances to practice-relevant ''real life'' samples

    International Nuclear Information System (INIS)

    Voss, I.; Altrogge, M.; Francke, W.

    1993-01-01

    Building on methods for the dehalogenisation of chlorinated benzoles known from the literature, an investigation was carried out whether polychlorinated biphenyls, dibenzo furane and dibenzo-p-dioxin can be dehalogenated electrochemically. The experiments were carried out with pure substances and transferred to mixed substances (real life samples). The investigations showed that both pure substances and complex mixtures can be dehalogenated without problems. Even in the presence of a clear oil matrix (e.g.: Oil trickled through a deposit), dehalogenisation of the xenobiotica present is possible. First attempts at 'scaling up' show that the method is also suitable in principle, for the disposal of large quantities of contaminated liquids. (BBR) [de

  7. [The influences of interaction during online gaming on sociability and aggression in real life].

    Science.gov (United States)

    Fuji, Kei; Yoshida, Fujio

    2010-02-01

    This study examined the influences of online gaming on sociability and aggression in real life. It was hypothesized that the effects of online gaming would differ depending on the interaction style of the online-gamers. Online-gamers in Japan (n = 1 477) were asked to respond to questionnaires that measured interaction style during online gaming, the effects of sociability and aggression, as well as social and individual orientation in real life. Factor analysis of the scores for interaction style extracted five factors. Covariance structure analysis indicated that sociable interactions such as "Broadening relations" and "Feeling of belonging" promoted sociability in real life. In addition, "Release from daily hassles" promoted sociability and decreased aggression. In contrast, non-sociable and aggressive interactions decreased sociability and increased aggression. The results also suggested that a social orientation in real life promoted sociable interactions during game playing, while an individual orientation promoted non-sociable and aggressive interactions. These results supported the hypotheses and suggested that online gaming resulted in positive outcomes for those who are socially, but negative outcomes for those who are not.

  8. Rich Vehicle Routing Problems and Applications

    DEFF Research Database (Denmark)

    Wen, Min

    very short computational time on real-life data involving up to 200 pairs of suppliers and customers. The second problem we consider is a dynamic vehicle routing problem with multiple objectives over a planning horizon that consists of multiple periods. In this problem, customer orders are revealed...... the company’s solution in terms of all the objectives, including the travel time, customer waiting and daily workload balances, under the given constraints considered in the work. Finally, we address an integrated vehicle routing and driver scheduling problem, in which a large number of practical constraints....... The method is implemented and tested on real-life data involving up to 2000 orders. It is shown that the method is able to provide solutions of good quality within reasonable running time....

  9. Real Life Lab BIPV field testing in the Netherlands

    NARCIS (Netherlands)

    Ritzen, M.; Vroon, Z.; Rovers, R.; Geurts, C.; Blocken, B.

    2015-01-01

    Integration of PV in the Building Envelope (BIPV) is one of the four key developments necessary for large market PV penetration, together with PV efficiency improvement, price decrease and electricity storage [1]. In the course of BIPV development, Real-Life Lab demonstration projects are realized

  10. Real life lab BIPV field testing in the Netherlands

    NARCIS (Netherlands)

    Ritzen, M.J.; Vroon, Z.; Geurts, C.P.W.; Rovers, R.; Blocken, B.J.E.

    2015-01-01

    Integration of PV in the Building Envelope (BIPV) is one of the four key developments necessary for large market PV penetration, together with PV efficiency improvement, price decrease and electricity storage [1]. In the course of BIPV development, Real-Life Lab demonstration projects are realized

  11. Late-Life and Life History Predictors of Older Adults of High-Risk Alcohol Consumption and Drinking Problems

    Science.gov (United States)

    Moos, Rudolf H.; Schutte, Kathleen K.; Brennan, Penny L.; Moos, Bernice S.

    2009-01-01

    Aims This prospective, longitudinal study focused on late-life and life history predictors of high-risk alcohol consumption and drinking problems during a 20-year interval as adults matured from age 55–65 to age 75–85. Design, Setting, Participants A sample of older community residents (N=719) who had consumed alcohol in the past year or shortly before was surveyed at baseline and 10 years and 20 years later. Measurements At each contact point, participants completed an inventory that assessed their alcohol consumption, drinking problems, and personal and life context factors. Participants also provided information about their life history of drinking and help-seeking. Results Older adults who, at baseline, had more friends who approved of drinking, relied on substances for tension reduction, and had more financial resources were more likely to engage in high-risk alcohol consumption and to incur drinking problems at 10-year and 20-year follow-ups. With respect to life history factors, drinking problems by age 50 were associated with a higher likelihood of late-life high-risk alcohol consumption and drinking problems; having tried to cut down on drinking and participation in Alcoholics Anonymous were associated with a lower likelihood of high-risk consumption and problems. Conclusion Specific late-life and life history factors can identify older adults likely to engage in excessive alcohol consumption 10 and 20 years later. Targeted screening that considers current alcohol consumption and life context, and history of drinking problems and help-seeking, could help identify older adults at higher risk for excessive or problematic drinking. PMID:19969428

  12. The Cost of Your Shirt. A Simulation Exercise for Secondary Students and Adults, Based on the Real-Life Drama of Guatemalan Textile Workers.

    Science.gov (United States)

    Swenson, Mary, Comp.; Austin, Jane, Comp.

    This simulation exercise requires participants to practice critical thinking, problem solving, and negotiating skills as they role play real-life conflicts concerning working conditions in a factory in Guatemala City, Guatemala. Participants also learn about Guatemala's history, its social, economic, and political status as of April 1994. Based on…

  13. In Patients with Cirrhosis, Driving Simulator Performance is Associated With Real-life Driving

    DEFF Research Database (Denmark)

    Lauridsen, Mette Enok Munk; Thacker, Leroy R; White, Melanie B

    2016-01-01

    BACKGROUND & AIMS: Minimal hepatic encephalopathy (MHE) has been linked to higher real-life rates of automobile crashes and poor performance in driving simulation studies, but the link between driving simulator performance and real-life automobile crashes has not been clearly established. Further......, not all patients with MHE are unsafe drivers, but it is unclear how to distinguish them from unsafe drivers. We investigated the link between performance on driving simulators and real-life automobile accidents and traffic violations. We also aimed to identify features of unsafe drivers with cirrhosis...... and evaluated changes in simulated driving skills and MHE status after 1 year. METHODS: We performed a study of outpatients with cirrhosis (n=205; median 55 years old; median model for end-stage liver disease score, 9.5; none with overt hepatic encephalopathy or alcohol or illicit drug use within previous 6...

  14. The Home Care Crew Scheduling Problem:

    DEFF Research Database (Denmark)

    Rasmussen, Matias Sevel; Justesen, Tor; Dohn, Anders

    In the Home Care Crew Scheduling Problem a staff of caretakers has to be assigned a number of visits to patients' homes, such that the overall service level is maximised. The problem is a generalisation of the vehicle routing problem with time windows. Required travel time between visits and time...... preference constraints. The algorithm is tested both on real-life problem instances and on generated test instances inspired by realistic settings. The use of the specialised branching scheme on real-life problems is novel. The visit clustering decreases run times significantly, and only gives a loss...... windows of the visits must be respected. The challenge when assigning visits to caretakers lies in the existence of soft preference constraints and in temporal dependencies between the start times of visits. We model the problem as a set partitioning problem with side constraints and develop an exact...

  15. Parallelization of mathematical library for generalized eigenvalue problem for real band matrices

    International Nuclear Information System (INIS)

    Tanaka, Yasuhisa.

    1997-05-01

    This research has focused on a parallelization of the mathematical library for a generalized eigenvalue problem for real band matrices on IBM SP and Hitachi SR2201. The origin of the library is LASO (Lanczos Algorithm with Selective Orthogonalization), which was developed on the basis of Block Lanczos method for standard eigenvalue problem for real band matrices at Texas University. We adopted D.O.F. (Degree Of Freedom) decomposition method for a parallelization of this library, and evaluated its parallel performance. (author)

  16. Speed Biases With Real-Life Video Clips

    Directory of Open Access Journals (Sweden)

    Federica Rossi

    2018-03-01

    Full Text Available We live almost literally immersed in an artificial visual world, especially motion pictures. In this exploratory study, we asked whether the best speed for reproducing a video is its original, shooting speed. By using adjustment and double staircase methods, we examined speed biases in viewing real-life video clips in three experiments, and assessed their robustness by manipulating visual and auditory factors. With the tested stimuli (short clips of human motion, mixed human-physical motion, physical motion and ego-motion, speed underestimation was the rule rather than the exception, although it depended largely on clip content, ranging on average from 2% (ego-motion to 32% (physical motion. Manipulating display size or adding arbitrary soundtracks did not modify these speed biases. Estimated speed was not correlated with estimated duration of these same video clips. These results indicate that the sense of speed for real-life video clips can be systematically biased, independently of the impression of elapsed time. Measuring subjective visual tempo may integrate traditional methods that assess time perception: speed biases may be exploited to develop a simple, objective test of reality flow, to be used for example in clinical and developmental contexts. From the perspective of video media, measuring speed biases may help to optimize video reproduction speed and validate “natural” video compression techniques based on sub-threshold temporal squeezing.

  17. Systems engineering real estate development projects

    Science.gov (United States)

    Gusakova, Elena; Titarenko, Boris; Stepanov, Vitaliy

    2017-10-01

    In recent years, real estate development has accumulated a wealth of experience in implementing major projects, which requires comprehension and systematization. The scientific instrument of system engineering is studied in the article and is substantively interpreted with reference to real estate development projects. The most perspective approaches and models are substantiated, allowing strategically to plan the life cycle of the project as a whole, and also to solve the engineering butt problems of the project. The relevance of further scientific studies of regularities and specifics of the life cycle of real estate development projects conducted at the Moscow State University of Economics and Management at the ISTA department is shown.

  18. Acoustic Coordinated Reset Neuromodulation in a Real Life Patient Population with Chronic Tonal Tinnitus

    Science.gov (United States)

    Hauptmann, Christian; Ströbel, Armin; Williams, Mark; Patel, Nitesh; Wurzer, Hannes; von Stackelberg, Tatjana; Brinkmann, Uwe; Langguth, Berthold; Tass, Peter A.

    2015-01-01

    Purpose. Primary tinnitus has a severe negative influence on the quality of life of a significant portion of the general population. Acoustic coordinated reset neuromodulation is designed to induce a long-lasting reduction of tinnitus symptoms. To test acoustic coordinated reset neuromodulation as a treatment for chronic, tonal tinnitus under real life conditions, an outpatient study “RESET Real Life” was commissioned by ANM GmbH. Herein we present the results of this study. Methods. In a prospective, open-label, nonrandomized, noncontrolled multicenter clinical study with 200 chronic tinnitus patients, tinnitus questionnaire TBF-12 and Global Clinical Improvement-Impression Scale (CGI-I7) are used to study the safety and efficacy of acoustic coordinated reset neuromodulation. 189 patients completed the last 12-month visit, 11 patients dropped out (8 because of nontreatment related reasons; 2 because tinnitus did not change; and 1 because tinnitus got louder). Results. Acoustic coordinated reset neuromodulation caused a statistically and clinically significant decrease in TBF-12 scores as well as in CGI-I7 after 12 months of therapy under real life conditions. There were no persistent adverse events reported that were related to the therapy. Conclusion. The field study “RESET Real Life” provides evidence for safety and efficacy of acoustic coordinated reset neuromodulation in a prospective, open-label, real life setting. PMID:26568958

  19. Life events, locus of control, and behavioral problems among Chinese adolescents.

    Science.gov (United States)

    Liu, X; Kurita, H; Uchiyama, M; Okawa, M; Liu, L; Ma, D

    2000-12-01

    This study examined associations of life events and locus of control with behavioral problems among 1,365 Chinese adolescents by using the Youth Self-Report (YSR), Adolescent Self-Rating Life Events Checklist (ASLEC), and the Nowicki-Strickland Locus of Control Scale for Children. Results indicated that the overall prevalence of behavioral and emotional problems was 10.7% (95% CI = 9.9-11.5%). Logistic-regression analyses showed that a total of 13 negative life events mainly coming from academic domain and interpersonal relationships, high life-stress score, and high external locus score significantly increased the risk for behavioral problems. Life stress and locus of control significantly interacted with behavioral problems. These findings support the linkage between stressful life events and psychopathology in a general population of adolescents from mainland China, and demonstrate the stress-moderating effects of locus of control on psychopathology as well.

  20. Intriguingly Real Life of the Queen of Crime

    Directory of Open Access Journals (Sweden)

    Branka Kovačević

    2016-12-01

    Full Text Available This December it will be ninety years since Agatha Christie disappeared for eleven days and despite the fact that there are many biographical books about her life and work, nobody knows for sure what provoked her to vanish, sending shockwaves in British society in 1926. Whatever the cause may be, this disappearance has remained a mystery and inspired French authors Anne Martinetti and Guillaume Lebeau, along with the illustrator Alexandre Franc, to create a graphic novel: Agatha: The Real Life of Agatha Christie. Marinetti has also written a cookbook inspired by Agatha Christie, entitled Creams and Punishments, while together with Lebeau, she has co-authored the encyclopedia Agatha Christie from A to Z.Agatha: The Real Life of Agatha Christie was originally released in 2014 as a French-language Kindle edition and was first published in English in May, 2016 by the UK press SelfMadeHero, which specializes in graphic novels and manga adaptations of classic literature, like those of Shakespeare, Poe and Kafka. The story is told through 112 illustrated pages and concludes with a thorough timeline of key events in Agatha Christie’s life, as well as a complete bibliography. It is noticeable that novels and story collections featuring Hercule Poirot take up the greater part of her bibliography. The authors of this biography assume a similar approach in showing the significance of this fictional character in Christie's career (and life, representing Poirot throughout the text as her companion and advisor without using any graphic techniques to stress the fictionality of his character. The authors make strong attempts to convey the close relationship that Christie built with her most prominent character, one who always seems to appear in this biography during her moments of extreme loneliness, and one to whom Christie owed a great deal – as she admited herself when she decided to buy the Greenway House in December 1938 (Martinetti, Lebeau, and Franc

  1. How Accumulated Real Life Stress Experience and Cognitive Speed Interact on Decision-Making Processes

    Directory of Open Access Journals (Sweden)

    Eva Friedel

    2017-06-01

    Full Text Available Rationale: Advances in neurocomputational modeling suggest that valuation systems for goal-directed (deliberative on one side, and habitual (automatic decision-making on the other side may rely on distinct computational strategies for reinforcement learning, namely model-free vs. model-based learning. As a key theoretical difference, the model-based system strongly demands cognitive functions to plan actions prospectively based on an internal cognitive model of the environment, whereas valuation in the model-free system relies on rather simple learning rules from operant conditioning to retrospectively associate actions with their outcomes and is thus cognitively less demanding. Acute stress reactivity is known to impair model-based but not model-free choice behavior, with higher working memory capacity protecting the model-based system from acute stress. However, it is not clear which impact accumulated real life stress has on model-free and model-based decision systems and how this influence interacts with cognitive abilities.Methods: We used a sequential decision-making task distinguishing relative contributions of both learning strategies to choice behavior, the Social Readjustment Rating Scale questionnaire to assess accumulated real life stress, and the Digit Symbol Substitution Test to test cognitive speed in 95 healthy subjects.Results: Individuals reporting high stress exposure who had low cognitive speed showed reduced model-based but increased model-free behavioral control. In contrast, subjects exposed to accumulated real life stress with high cognitive speed displayed increased model-based performance but reduced model-free control.Conclusion: These findings suggest that accumulated real life stress exposure can enhance reliance on cognitive speed for model-based computations, which may ultimately protect the model-based system from the detrimental influences of accumulated real life stress. The combination of accumulated real life

  2. How Accumulated Real Life Stress Experience and Cognitive Speed Interact on Decision-Making Processes.

    Science.gov (United States)

    Friedel, Eva; Sebold, Miriam; Kuitunen-Paul, Sören; Nebe, Stephan; Veer, Ilya M; Zimmermann, Ulrich S; Schlagenhauf, Florian; Smolka, Michael N; Rapp, Michael; Walter, Henrik; Heinz, Andreas

    2017-01-01

    Rationale: Advances in neurocomputational modeling suggest that valuation systems for goal-directed (deliberative) on one side, and habitual (automatic) decision-making on the other side may rely on distinct computational strategies for reinforcement learning, namely model-free vs. model-based learning. As a key theoretical difference, the model-based system strongly demands cognitive functions to plan actions prospectively based on an internal cognitive model of the environment, whereas valuation in the model-free system relies on rather simple learning rules from operant conditioning to retrospectively associate actions with their outcomes and is thus cognitively less demanding. Acute stress reactivity is known to impair model-based but not model-free choice behavior, with higher working memory capacity protecting the model-based system from acute stress. However, it is not clear which impact accumulated real life stress has on model-free and model-based decision systems and how this influence interacts with cognitive abilities. Methods: We used a sequential decision-making task distinguishing relative contributions of both learning strategies to choice behavior, the Social Readjustment Rating Scale questionnaire to assess accumulated real life stress, and the Digit Symbol Substitution Test to test cognitive speed in 95 healthy subjects. Results: Individuals reporting high stress exposure who had low cognitive speed showed reduced model-based but increased model-free behavioral control. In contrast, subjects exposed to accumulated real life stress with high cognitive speed displayed increased model-based performance but reduced model-free control. Conclusion: These findings suggest that accumulated real life stress exposure can enhance reliance on cognitive speed for model-based computations, which may ultimately protect the model-based system from the detrimental influences of accumulated real life stress. The combination of accumulated real life stress exposure

  3. The Real World around me – Life within the Pixel?

    Directory of Open Access Journals (Sweden)

    Aleksandra Bokan

    2015-09-01

    Full Text Available Modern era, the famous 21st century is full of options. Never more features and never greater alienation. Is it really so? While living in their standard-progress that, but when it towered over the black shadow, and when you are able to save someone’s life, tripping locked mechanisms for social survival. It no longer matters whether someone look at someone elses’s pictures from the wedding, showing a new hairstyle on FB or Twitter etc. Simply put, life on the Internet becomes a means of saving someone’s real, tangible life.

  4. High correlation between performance on a virtual-reality simulator and real-life cataract surgery

    DEFF Research Database (Denmark)

    Thomsen, Ann Sofia Skou; Smith, Phillip; Subhi, Yousif

    2017-01-01

    -tracking software of cataract surgical videos with a Pearson correlation coefficient of -0.70 (p = 0.017). CONCLUSION: Performance on the EyeSi simulator is significantly and highly correlated to real-life surgical performance. However, it is recommended that performance assessments are made using multiple data......PURPOSE: To investigate the correlation in performance of cataract surgery between a virtual-reality simulator and real-life surgery using two objective assessment tools with evidence of validity. METHODS: Cataract surgeons with varying levels of experience were included in the study. All...... antitremor training, forceps training, bimanual training, capsulorhexis and phaco divide and conquer. RESULTS: Eleven surgeons were enrolled. After a designated warm-up period, the proficiency-based test on the EyeSi simulator was strongly correlated to real-life performance measured by motion...

  5. Cognitive Backgrounds of Problem Solving: A Comparison of Open-Ended vs. Closed Mathematics Problems

    Science.gov (United States)

    Bahar, Abdulkadir; Maker, C. June

    2015-01-01

    Problem solving has been a core theme in education for several decades. Educators and policy makers agree on the importance of the role of problem solving skills for school and real life success. A primary purpose of this study was to investigate the influence of cognitive abilities on mathematical problem solving performance of elementary…

  6. Violence exposure in real-life, video games, television, movies, and the internet: is there desensitization?

    Science.gov (United States)

    Funk, Jeanne B; Baldacci, Heidi Bechtoldt; Pasold, Tracie; Baumgardner, Jennifer

    2004-02-01

    It is believed that repeated exposure to real-life and to entertainment violence may alter cognitive, affective, and behavioral processes, possibly leading to desensitization. The goal of the present study was to determine if there are relationships between real-life and media violence exposure and desensitization as reflected in related characteristics. One hundred fifty fourth and fifth graders completed measures of real-life violence exposure, media violence exposure, empathy, and attitudes towards violence. Regression analyses indicated that only exposure to video game violence was associated with (lower) empathy. Both video game and movie violence exposure were associated with stronger proviolence attitudes. The active nature of playing video games, intense engagement, and the tendency to be translated into fantasy play may explain negative impact, though causality was not investigated in the present design. The samples' relatively low exposure to real-life violence may have limited the identification of relationships. Although difficult to quantify, desensitization to violence should be further studied using related characteristics as in the present study. Individual differences and causal relationships should also be examined.

  7. Quality of life improvement after a three-year course of sublingual immunotherapy in patients with house dust mite and grass pollen induced allergic rhinitis: results from real-life.

    Science.gov (United States)

    Novakova, Silviya Mihaylova; Staevska, Maria Toncheva; Novakova, Plamena Ivanova; Yoncheva, Manuela Dimitrova; Bratoycheva, Maria Stoykova; Musurlieva, Nina Mihaylova; Tzekov, Valeri Dimitrov; Nicolov, Dimitar Georgiev

    2017-09-29

    Along with its high prevalence, the burden of allergic rhinitis rests upon the serious impact on quality of life of patients. Allergic rhinitis is associated with impairments in daily activities, work and school performance, and practical problems. Patients suffer from sleep disorders and emotional problems. Тhe advantages of sublingual immunotherapy on quality of life have only recently begun to emerge. The objective of this prospective real-life study was to evaluate the effect of a three-year course of sublingual immunotherapy with house dust mite (HDM) and grass pollen extracts on quality of life in adults with allergic rhinitis. A total number of 191 adult patients [105 (54,979%) men; mean age 27.3 years (SD-6.14)] with moderate to severe allergic rhinitis and clinically relevant sensitization to house dust mites or grass pollen were prospectively evaluated in the course of management of their disease. Health-related quality of life was assessed by Rhinoconjunctivitis Quality of Life Questionnaire at baseline and after three-year course of sublingual immunotherapy. The mean overall Qol score assessed at baseline and at the end of the third year of treatment decreased significantly in patients treated with HDM extract (from 2.95 to 0.76) as well as with Grass pollen extract (from 2.83 to 1.22) (р life provided evidence that a three-year course of SLIT with HDM extract as well as with grass pollen extract significantly increased QoL in patients with allergic rhinitis.

  8. Methods of modeling TCO residential real estate in the life cycles of buildings as a promising energy efficiency management tool

    Directory of Open Access Journals (Sweden)

    Kulakov Kirill

    2017-01-01

    Full Text Available Building and developing an affordable housing market is a huge challenge for Russia’s national economy. Today, the housing construction industry finds itself in a situation torn by a conflict caused by the simultaneous needs to minimize the housing construction costs in order to make housing more affordable for Russians and to increase the energy efficiency of the housing projects, which is associated with additional costs for developers. To find solutions to this contradictory situation, one needs new theoretical and practical approaches and economic tools. The global economic trend of managing goods and services on the basis of the value of goods and services over the life cycle is also manifested in the construction industry in Russia. The problem of forming a new economic thinking in the housing sector predetermines the perception of the value of housing not only as the price of purchased real estate, but as the equivalent of the total cost of ownership of real estate throughout its life cycle. This approach allows to compensate the initial rise in the cost of construction resulting from the introduction of energy-efficient technologies by savings in the operational phase of the life cycle of the property. In this regard, management of the total cost of real estate ownership based on energy modeling is of high research and practical relevance.

  9. Sharing skills and knowledge to confront real-world problems | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sharing skills and knowledge to confront real-world problems ... because 1.3 billion people cannot read English, and only 163 million people (a fraction ... childhood obesity in urban areas, caused by increases in junk food and lack of exercise.

  10. The balanced academic curriculum problem revisited

    DEFF Research Database (Denmark)

    Chiarandini, Marco; Di Gaspero, Luca; Gualandi, Stefano

    2012-01-01

    The Balanced Academic Curriculum Problem (BACP) consists in assigning courses to teaching terms satisfying prerequisites and balancing the credit course load within each term. The BACP is part of the CSPLib with three benchmark instances, but its formulation is simpler than the problem solved...... in practice by universities. In this article, we introduce a generalized version of the problem that takes different curricula and professor preferences into account, and we provide a set of real-life problem instances arisen at University of Udine. Since the existing formulation based on a min-max objective...... function does not balance effectively the credit load for the new instances, we also propose alternative objective functions. Whereas all the CSPLib instances are efficiently solved with Integer Linear Programming (ILP) state-of-the-art solvers, our new set of real-life instances turns out to be much more...

  11. Operation of ULCS - real life

    Directory of Open Access Journals (Sweden)

    Jasna Prpić-Oršić

    2014-12-01

    Full Text Available In this paper the real life operation of ULCS (Ultra Large Container Ships is presented from the point of view of shipmasters. The paper provides interpretation of results of questionnaire filled by masters of large container ships during Tools for Ultra Large Container Ships (TULC EUI FP7 project. This is done in a way that results of questionnaire are further reviewed and commented by experienced master of ULCS. Following phenomena are subject of questionnaire and further discussed in the paper: parametric rolling, slamming, whipping, springing, green water and rogue waves. Special attention is given to the definition of rough sea states as well as to measures that ship masters take to avoid them as well as to the manoeuvring in heavy seas. The role of the wave forecast and weather routing software is also discussed.

  12. An adaptation framework for turning Real-Life Events into Games

    DEFF Research Database (Denmark)

    Kjærhus Therkildsen, Sacha; Cassøe Bunkenborg, Nanna; Larsen, Lasse Juel

    method and participatory design to achieve our ambition. In conclusion we found that a framework for persuasive board games can be advanced by balancing five interrelated layers: 1) real life events (game fiction), 2) rules (formal game elements), 3) movement system (game mechanisms), 4) destiny...

  13. Is fear in your head? A comparison of instructed and real-life expressions of emotion in the face and body.

    Science.gov (United States)

    Abramson, Lior; Marom, Inbal; Petranker, Rotem; Aviezer, Hillel

    2017-04-01

    The majority of emotion perception studies utilize instructed and stereotypical expressions of faces or bodies. While such stimuli are highly standardized and well-recognized, their resemblance to real-life expressions of emotion remains unknown. Here we examined facial and body expressions of fear and anger during real-life situations and compared their recognition to that of instructed expressions of the same emotions. In order to examine the source of the affective signal, expressions of emotion were presented as faces alone, bodies alone, and naturally, as faces with bodies. The results demonstrated striking deviations between recognition of instructed and real-life stimuli, which differed as a function of the emotion expressed. In real-life fearful expressions of emotion, bodies were far better recognized than faces, a pattern not found with instructed expressions of emotion. Anger reactions were better recognized from the body than from the face in both real-life and instructed stimuli. However, the real-life stimuli were overall better recognized than their instructed counterparts. These results indicate that differences between instructed and real-life expressions of emotion are prevalent and raise caution against an overreliance of researchers on instructed affective stimuli. The findings also demonstrate that in real life, facial expression perception may rely heavily on information from the contextualizing body. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  14. METHOD FOR SOLVING FUZZY ASSIGNMENT PROBLEM USING MAGNITUDE RANKING TECHNIQUE

    OpenAIRE

    D. Selvi; R. Queen Mary; G. Velammal

    2017-01-01

    Assignment problems have various applications in the real world because of their wide applicability in industry, commerce, management science, etc. Traditional classical assignment problems cannot be successfully used for real life problem, hence the use of fuzzy assignment problems is more appropriate. In this paper, the fuzzy assignment problem is formulated to crisp assignment problem using Magnitude Ranking technique and Hungarian method has been applied to find an optimal solution. The N...

  15. Problem based learning: the effect of real time data on the website to student independence

    Science.gov (United States)

    Setyowidodo, I.; Pramesti, Y. S.; Handayani, A. D.

    2018-05-01

    Learning science developed as an integrative science rather than disciplinary education, the reality of the nation character development has not been able to form a more creative and independent Indonesian man. Problem Based Learning based on real time data in the website is a learning method focuses on developing high-level thinking skills in problem-oriented situations by integrating technology in learning. The essence of this study is the presentation of authentic problems in the real time data situation in the website. The purpose of this research is to develop student independence through Problem Based Learning based on real time data in website. The type of this research is development research with implementation using purposive sampling technique. Based on the study there is an increase in student self-reliance, where the students in very high category is 47% and in the high category is 53%. This learning method can be said to be effective in improving students learning independence in problem-oriented situations.

  16. Definition of life law and the situation with problems of China's life jurisprudence.

    Science.gov (United States)

    Liu, Changqiu

    2008-12-01

    Life law is a new conception brought by the development of modern life science and biotechnology. There are many different ideas on the conception of life law in academy. The definition of life law should be footed on the domain of bioethics. Based on bioethics, life law is a group of legislations which are enacted or acknowledged by the state and implemented by the state compulsively with the goal of regulating all types of relations revolving the survival as well as terminal of human beings and some other creatures which play important roles in the maintenance of human's life and health. There are many problems in China's study on science of life law, which need paying special attention to by China's scholars.

  17. The quality of life of adolescents with menstrual problems.

    Science.gov (United States)

    Nur Azurah, Abdul Ghani; Sanci, Lena; Moore, Elya; Grover, Sonia

    2013-04-01

    To date, very few publications have examined the health related quality of life (HRQL) in the younger population with menstrual problems, despite their high prevalence in adolescent girls. We describe the health-related quality of life (HRQL) among adolescents with menstrual problems and identified factors that have an impact on it. The study was a questionnaire study (using PedsQL 4.0) of adolescents aged 13-18 referred to a tertiary gynecology center for menstrual problems between June 2009 and August 2010. One hundred eighty-four adolescents completed the questionnaires. The mean age was 15.10 ± 1.49 with the mean body mass index (BMI) of 22.83 ± 4.82 kg/m(2). The most common menstrual problems seen in the clinic were dysmenorrhea (38.6%) followed by heavy bleeding (33.6%), oligomenorrhea (19.6%), and amenorrhea (8.2%). The mean overall score was 70.40 ± 16.36 with 42.3% having a score below 1 standard deviation (SD) from the norms. Adolescents with dysmenorrhea had the poorest score in physical function, whereas those with amenorrhea had the lowest score in psychosocial function. Maternal parenting style, parental anxiety, adolescents' ill-health behavior, and BMI have been found to have impact on the girls' quality of life (QoL). Although menstrual problems are not life threatening, they can pose a significant impact on the quality of life of these patients. Identification of these impacts might lead to the recognition of potential services or education to improve this. Understanding the characteristics that predict QoL may help a clinician identify patients who are risk for poor QoL. Copyright © 2013 North American Society for Pediatric and Adolescent Gynecology. All rights reserved.

  18. Wrongful life: the problem of causation.

    Science.gov (United States)

    Mason, J K

    2004-01-01

    The paper considers the status of the wrongful life action particularly in the light of the recent acceptance of such actions in continental Europe. It is considered that the hurdle of causation is still not adequately overcome in these cases and, in a search for an answer to the difficulty, the author re-examines the Canadian case of Cherry v Borsman. This case was originally thought of as one of wrongful life associated with a negligently performed abortion and the paper attempts to overcome the problems of causation by comparing and contrasting the roles of the genetic counsellor and the abortionist. While the attempt is by no means wholly successful, it also serves to draw attention to some significant differences between wrongful life actions based on physical and mental disability in the neonate.

  19. Using Problem-solving Therapy to Improve Problem-solving Orientation, Problem-solving Skills and Quality of Life in Older Hemodialysis Patients.

    Science.gov (United States)

    Erdley-Kass, Shiloh D; Kass, Darrin S; Gellis, Zvi D; Bogner, Hillary A; Berger, Andrea; Perkins, Robert M

    2017-08-24

    To determine the effectiveness of Problem-Solving Therapy (PST) in older hemodialysis (HD) patients by assessing changes in health-related quality of life and problem-solving skills. 33 HD patients in an outpatient hemodialysis center without active medical and psychiatric illness were enrolled. The intervention group (n = 15) received PST from a licensed social worker for 6 weeks, whereas the control group (n = 18) received usual care treatment. In comparison to the control group, patients receiving PST intervention reported improved perceptions of mental health, were more likely to view their problems with a positive orientation and were more likely to use functional problem-solving methods. Furthermore, this group was also more likely to view their overall health, activity limits, social activities and ability to accomplish desired tasks with a more positive mindset. The results demonstrate that PST may positively impact mental health components of quality of life and problem-solving coping among older HD patients. PST is an effective, efficient, and easy to implement intervention that can benefit problem-solving abilities and mental health-related quality of life in older HD patients. In turn, this will help patients manage their daily living activities related to their medical condition and reduce daily stressors.

  20. In Patients With Cirrhosis, Driving Simulator Performance Is Associated With Real-life Driving.

    Science.gov (United States)

    Lauridsen, Mette M; Thacker, Leroy R; White, Melanie B; Unser, Ariel; Sterling, Richard K; Stravitz, Richard T; Matherly, Scott; Puri, Puneet; Sanyal, Arun J; Gavis, Edith A; Luketic, Velimir; Siddiqui, Muhammad S; Heuman, Douglas M; Fuchs, Michael; Bajaj, Jasmohan S

    2016-05-01

    Minimal hepatic encephalopathy (MHE) has been linked to higher real-life rates of automobile crashes and poor performance in driving simulation studies, but the link between driving simulator performance and real-life automobile crashes has not been clearly established. Furthermore, not all patients with MHE are unsafe drivers, but it is unclear how to distinguish them from unsafe drivers. We investigated the link between performance on driving simulators and real-life automobile accidents and traffic violations. We also aimed to identify features of unsafe drivers with cirrhosis and evaluated changes in simulated driving skills and MHE status after 1 year. We performed a study of outpatients with cirrhosis (n = 205; median 55 years old; median model for end-stage liver disease score, 9.5; none with overt hepatic encephalopathy or alcohol or illicit drug use within previous 6 months) seen at the Virginia Commonwealth University and McGuire Veterans Administration Medical Center, from November 2008 through April 2014. All participants were given paper-pencil tests to diagnose MHE (98 had MHE; 48%), and 163 patients completed a standardized driving simulation. Data were collected on traffic violations and automobile accidents from the Virginia Department of Motor Vehicles and from participants' self-assessments when they entered the study, and from 73 participants 1 year later. Participants also completed a questionnaire about alcohol use and cessation patterns. The driving simulator measured crashes, run-time, road center and edge excursions, and illegal turns during navigation; before and after each driving simulation session, patients were asked to rate their overall driving skills. Drivers were classified as safe or unsafe based on crashes and violations reported on official driving records; simulation results were compared with real-life driving records. Multivariable regression analyses of real-life crashes and violations was performed using data on

  1. Problem-solving with multiple interdependent criteria: better solution to complex problems

    International Nuclear Information System (INIS)

    Carlsson, C.; Fuller, R.

    1996-01-01

    We consider multiple objective programming (MOP) problems with additive interdependencies, this is when the states of some chosen objective are attained through supportive or inhibitory feed-backs from several other objectives. MOP problems with independent objectives (when the cause-effect relations between the decision variables and the objectives are completely known) will be treated as special cases of the MOP in which we have interdependent objectives. We illustrate our ideas by a simple three-objective real-life problem

  2. The Forms and Functions of Real-Life Moral Decision-Making.

    Science.gov (United States)

    Krebs, Dennis L.; Denton, Kathy; Wark, Gillian

    1997-01-01

    Observes that the Kohlbergian model of morality does not give a good account of the ways in which people make moral decisions in their everyday lives. Argues that a functional model of moral judgment and moral behavior derived from evolutionary theory may supply a better account of real-life morality. (DSK)

  3. AVEC 2017 - Real-life depression, and affect recognition workshop and challenge

    NARCIS (Netherlands)

    Ringeval, Fabien; Schuller, Bjorn; Valstar, Michel; Gratch, Jonathan; Cowie, Roddy; Scherer, Stefan; Mozgai, Sharon; Cummins, Nicholas; Schmitt, Maximilian; Pantic, Maja

    2017-01-01

    The Audio/Visual Emotion Challenge and Workshop (AVEC 2017) "Real-life depression, and affect" will be the seventh competition event aimed at comparison of multimedia processing and machine learning methods for automatic audiovisual depression and emotion analysis, with all participants competing

  4. Real-Life/Real-Time Elderly Fall Detection with a Triaxial Accelerometer.

    Science.gov (United States)

    Sucerquia, Angela; López, José David; Vargas-Bonilla, Jesús Francisco

    2018-04-05

    The consequences of a fall on an elderly person can be reduced if the accident is attended by medical personnel within the first hour. Independent elderly people often stay alone for long periods of time, being in more risk if they suffer a fall. The literature offers several approaches for detecting falls with embedded devices or smartphones using a triaxial accelerometer. Most of these approaches have not been tested with the target population or cannot be feasibly implemented in real-life conditions. In this work, we propose a fall detection methodology based on a non-linear classification feature and a Kalman filter with a periodicity detector to reduce the false positive rate. This methodology requires a sampling rate of only 25 Hz; it does not require large computations or memory and it is robust among devices. We tested our approach with the SisFall dataset achieving 99.4% of accuracy. We then validated it with a new round of simulated activities with young adults and an elderly person. Finally, we give the devices to three elderly persons for full-day validations. They continued with their normal life and the devices behaved as expected.

  5. Effects of stress management training and problem solving on quality of life and life expectancy among infertile women

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Zarbakhsh Bahri

    2013-08-01

    Full Text Available Introduction: This study aims to evaluate the effectiveness of stress management training and problem-solving training on quality of life and life expectancy of infertile women was conducted.Material and Methods: The method of this study was experimental with pretest – posttest design with a control group. population of 400 infertile women who referred to infertility center in Rasht were randomized to 250 of them were selected and the quality of life and life expectancy of the study were the 45 members of the quality of life and life expectancy lower were more randomly in three groups of 15 people, including two experimental groups and one control group were replaced. Each experimental groups were trained for 10 sessions of 90 minutes, respectively, stress management and problem-solving. Upon completion of the training program, participants were assessed again.Results: The result of present study showed that there was a significant difference between the experimental groups and control group in the scores of quality of life and life expectancy (p0.05.Conclusion: Stress management and problem solving training were effective on life expectancy and quality of life of infertile women but there was no significant difference between the effectiveness of these two methods on life expectancy and quality of life of infertile women.

  6. Emotional Problems, Quality of Life, and Symptom Burden in Patients With Lung Cancer.

    Science.gov (United States)

    Morrison, Eleshia J; Novotny, Paul J; Sloan, Jeff A; Yang, Ping; Patten, Christi A; Ruddy, Kathryn J; Clark, Matthew M

    2017-09-01

    Lung cancer is associated with a greater symptom burden than other cancers, yet little is known about the prevalence of emotional problems and how emotional problems may be related to the physical symptom burden and quality of life in newly diagnosed patients with lung cancer. This study aimed to identify the patient and disease characteristics of patients with lung cancer experiencing emotional problems and to examine how emotional problems relate to quality of life and symptom burden. A total of 2205 newly diagnosed patients with lung cancer completed questionnaires on emotional problems, quality of life, and symptom burden. Emotional problems at diagnosis were associated with younger age, female gender, current cigarette smoking, current employment, advanced lung cancer disease, surgical or chemotherapy treatment, and a lower Eastern Cooperative Oncology Group performance score. Additionally, strong associations were found between greater severity of emotional problems, lower quality of life, and greater symptom burden. Certain characteristics place patients with lung cancer at greater risk for emotional problems, which are associated with a reduced quality of life and greater symptom burden. Assessment of the presence of emotional problems at the time of lung cancer diagnosis provides the opportunity to offer tailored strategies for managing negative mood, and for improving the quality of life and symptom burden management of patients with lung cancer. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Rehabilitation in the real-life environment of a shopping mall.

    Science.gov (United States)

    Labbé, Delphine; Poldma, Tiiu; Fichten, Catherine; Havel, Alice; Kehayia, Eva; Mazer, Barbara; McKinley, Patricia; Rochette, Annie; Swaine, Bonnie

    2018-04-01

    The aim of this study was to explore how shopping malls could be used during rehabilitation and to identify the facilitators and barriers to their use. Two focus groups, conducted with 15 rehabilitation professionals from various disciplines and working with people with disabilities of all ages were structured around two topics: (i) The usage of malls for rehabilitation and (ii) Factors that facilitate or limit rehabilitation professionals' use of the mall as an environment for clinical assessment and/or intervention. The thematic analysis revealed that shopping malls were used to achieve several rehabilitation goals targeting physical and cognitive skills, psychological health and socialization. This real-life environment is motivating and helps foster independence and normalization. Factors affecting mall use during rehabilitation included personal factors (e.g. clients' personality and level of readiness) and environmental factors (e.g. clinical context, accessibility of the mall and social attitudes of store owners). Shopping malls may be a relevant rehabilitation assessment and treatment environment that could contribute to optimizing community integration of people with disabilities. Implications for rehabilitation To ensure successful community reintegration, clients could be trained at some point during their rehabilitation, to perform activities in real-life settings, such as a shopping mall. Shopping malls appear to enable the attainment of rehabilitation goals targeting a variety of skills. This real-life environment appears to be motivating and helps foster independence and normalization. Factors felt to affect mall use during rehabilitation include personal factors (e.g. clients' personality and level of readiness) and environmental factors (e.g. clinical context, accessibility of the mall and social attitudes of store owners). The shopping mall may be an untapped resource as it appears to be a relevant rehabilitation assessment and treatment

  8. A Comparison of Online Social Networks and Real-Life Social Networks: A Study of Sina Microblogging

    Directory of Open Access Journals (Sweden)

    Dayong Zhang

    2014-01-01

    Full Text Available Online social networks appear to enrich our social life, which raises the question whether they remove cognitive constraints on human communication and improve human social capabilities. In this paper, we analyze the users' following and followed relationships based on the data of Sina Microblogging and reveal several structural properties of Sina Microblogging. Compared with real-life social networks, our results confirm some similar features. However, Sina Microblogging also shows its own specialties, such as hierarchical structure and degree disassortativity, which all mark a deviation from real-life social networks. The low cost of the online network forms a broader perspective, and the one-way link relationships make it easy to spread information, but the online social network does not make too much difference in the creation of strong interpersonal relationships. Finally, we describe the mechanisms for the formation of these characteristics and discuss the implications of these structural properties for the real-life social networks.

  9. Learning based upon projects of architectural conservation: from university to real life

    OpenAIRE

    Mileto, Camilla; Vegas López-Manzanares, Fernando; Cristini, Valentina; Diodato, Maria

    2011-01-01

    Mileto, C.; Vegas López-Manzanares, F.; Cristini, V.; Diodato, M. (2011). Learning based upon projects of architectural conservation: from university to real life. IATED. 1-8. http://hdl.handle.net/10251/50072 Senia 1 8

  10. Between life and death: problems with live forensics between life and death

    CSIR Research Space (South Africa)

    Lessing, M

    2008-11-01

    Full Text Available stream_source_info Lessing1_2008.pdf.txt stream_content_type text/plain stream_size 6415 Content-Encoding UTF-8 stream_name Lessing1_2008.pdf.txt Content-Type text/plain; charset=UTF-8 Between Life and Death Problems...

  11. Accounting Theory: An Ethical Perspective of Real Life Scenarios

    Directory of Open Access Journals (Sweden)

    Shivneil Kumar Raj

    2016-11-01

    Full Text Available Decisions are made daily in businesses and individuals do encounter situations where they are faced with ethical issues. The subject is how one evaluates whether an act is ethical or unethical. This research article discusses real life ethical dilemmas that could be faced in accounting or business environment and applicability of various theories of ethics that were taught in accounting theory course in the undergraduate accounting program. The researcher employs a number of case studies highlighting the stories related to ethics that have been experienced in the past working life. Teleological and deontological theories are being used to explain how one could identify that a particular act is ethical or unethical. The work of accountants requires them to maintain high level of ethics to ensure integrity of the profession.

  12. Solving Real Community Problems to Improve the Teaching of Public Affairs

    Science.gov (United States)

    Yaghi, Abdulfattah; Alibeli, Madalla

    2014-01-01

    In order to achieve their course learning outcomes, public affairs instructors can train students to solve real community problems (SRCP). This approach focuses on the learners themselves and aims to transform the role of college professors from traditional teaching (lecturing) to facilitating and coaching students' learning activities. This study…

  13. Speech Recognition in Real-Life Background Noise by Young and Middle-Aged Adults with Normal Hearing

    OpenAIRE

    Lee, Ji Young; Lee, Jin Tae; Heo, Hye Jeong; Choi, Chul-Hee; Choi, Seong Hee; Lee, Kyungjae

    2015-01-01

    Background and Objectives People usually converse in real-life background noise. They experience more difficulty understanding speech in noise than in a quiet environment. The present study investigated how speech recognition in real-life background noise is affected by the type of noise, signal-to-noise ratio (SNR), and age. Subjects and Methods Eighteen young adults and fifteen middle-aged adults with normal hearing participated in the present study. Three types of noise [subway noise, vacu...

  14. British pharmacists' work-life balance - is it a problem?

    Science.gov (United States)

    Seston, Elizabeth; Hassell, Karen

    2014-04-01

    Using a validated tool, the study aimed to explore pharmacists' experiences of maintaining work/life balance in a large, nationally representative sample of pharmacists in Great Britain (GB). A two-page postal questionnaire was sent in 2008 to all GB-domiciled pharmacists who were registered with the regulatory body for pharmacy in GB (just over 44 000 pharmacists). Demographic information, work patterns and other employment data were collected and analysed using regression techniques to explore the link between these characteristics and a validated measure of work/life balance. The response rate to the census was 69.6% (n = 30 517). Eighty-three per cent (n = 25 243) of respondents were working as a pharmacist and were therefore eligible to complete the work/life balance statements. The results reported here relate to 12 364 individuals who had full data for the work/life balance scale and the demographic and work variables. Findings indicate that age, ethnicity, having caring responsibilities, sector of practice, hours of work and type of job are significant predictors of work/life balance problems. Pharmacy employers and government should recognise the changing demographic characteristics of the profession and consider what support might be available to the workforce to help alleviate work/life balance problems being experienced by certain groups of pharmacists. © 2013 Royal Pharmaceutical Society.

  15. Psychological needs, purpose in life, and problem video game playing among Chinese young adults.

    Science.gov (United States)

    Wu, Anise M S; Lei, Lamis L M; Ku, Lisbeth

    2013-01-01

    The negative impacts of excessive and problematic video game playing on both children and adults are attracting increasing concern. Based on self-determination theory (SDT; Ryan & Deci, 2000), this study hypothesized that the three basic psychological needs of autonomy, competence, and relatedness are positively associated with purpose in life, which in turn acts as a protective factor against problem video game playing among Chinese young adult players. Through a questionnaire survey with a sample of 165 Chinese adults aged between 18 and 30 years (mean age = 22.7 years), we found that perceived autonomy, competence, relatedness, and purpose in life were all negatively correlated with problem game playing. The demographic and psychological factors explained 38% of the variances of problem game playing. Specifically, gender, perceived relatedness, and purpose in life emerged as the three most salient predictors of problem game playing among the Chinese young adults. The mediating role of purpose in life was evidenced and it was found that purpose in life mediated the influences of the psychological needs proposed by SDT on problem game playing. Moreover, young men were significantly more susceptible to problem game playing than their female counterparts. To conclude, psychological needs and purpose in life influenced Chinese young adults' vulnerability to problem game playing directly or indirectly. Intervention programs that encourage social involvement and voluntary work, as well as counseling service that helps clients to search for life purpose, are suggested for intervening in problem game playing among Chinese young adults.

  16. Integrating Problem-Based Learning and Simulation: Effects on Student Motivation and Life Skills.

    Science.gov (United States)

    Roh, Young Sook; Kim, Sang Suk

    2015-07-01

    Previous research has suggested that a teaching strategy integrating problem-based learning and simulation may be superior to traditional lecture. The purpose of this study was to assess learner motivation and life skills before and after taking a course involving problem-based learning and simulation. The design used repeated measures with a convenience sample of 83 second-year nursing students who completed the integrated course. Data from a self-administered questionnaire measuring learner motivation and life skills were collected at pretest, post-problem-based learning, and post-simulation time points. Repeated-measures analysis of variance determined that the mean scores for total learner motivation (F=6.62, P=.003), communication (F=8.27, Plearning (F=4.45, P=.016) differed significantly between time points. Post hoc tests using the Bonferroni correction revealed that total learner motivation and total life skills significantly increased both from pretest to postsimulation and from post-problem-based learning test to postsimulation test. Subscales of learner motivation and life skills, intrinsic goal orientation, self-efficacy for learning and performance, problem-solving skills, and self-directed learning skills significantly increased both from pretest to postsimulation test and from post-problem-based learning test to post-simulation test. The results demonstrate that an integrating problem-based learning and simulation course elicits significant improvement in learner motivation and life skills. Simulation plus problem-based learning is more effective than problem-based learning alone at increasing intrinsic goal orientation, task value, self-efficacy for learning and performance, problem solving, and self-directed learning.

  17. Real-life applications with membrane computing

    CERN Document Server

    Zhang, Gexiang; Gheorghe, Marian

    2017-01-01

    This book thoroughly investigates the underlying theoretical basis of membrane computing models, and reveals their latest applications. In addition, to date there have been no illustrative case studies or complex real-life applications that capitalize on the full potential of the sophisticated membrane systems computational apparatus; gaps that this book remedies. By studying various complex applications – including engineering optimization, power systems fault diagnosis, mobile robot controller design, and complex biological systems involving data modeling and process interactions – the book also extends the capabilities of membrane systems models with features such as formal verification techniques, evolutionary approaches, and fuzzy reasoning methods. As such, the book offers a comprehensive and up-to-date guide for all researchers, PhDs and undergraduate students in the fields of computer science, engineering and the bio-sciences who are interested in the applications of natural computing models.

  18. Mood effects on memory and executive control in a real-life situation.

    Science.gov (United States)

    Lagner, Prune; Kliegel, Matthias; Phillips, Louise H; Ihle, Andreas; Hering, Alexandra; Ballhausen, Nicola; Schnitzspahn, Katharina M

    2015-01-01

    In the laboratory, studies have shown an inconsistent pattern of whether, and how, mood may affect cognitive functions indicating both mood-related enhancement as well as decline. Surprisingly, little is known about whether there are similar effects in everyday life. Hence, the present study aimed to investigate possible mood effects on memory and executive control in a real-life situation. Mood effects were examined in the context of winning in a sports competition. Sixty-one male handball players were tested with an extensive cognitive test battery (comprising memory and executive control) both after winning a match and after training as neutral baseline. Mood differed significantly between the two testing situations, while physiological arousal and motivation were comparable. Results showed lowered performance after the win compared with training in selected cognitive measures. Specifically, short-term and episodic memory performance was poorer following a win, whereas executive control performance was unaffected by condition. Differences in memory disappeared when emotional states after the match were entered as covariates into the initial analyses. Thus, findings suggest mood-related impairments in memory, but not in executive control processes after a positive real-life event.

  19. Social anxiety in online and real-life interaction and their associated factors.

    Science.gov (United States)

    Yen, Ju-Yu; Yen, Cheng-Fang; Chen, Cheng-Sheng; Wang, Peng-Wei; Chang, Yi-Hsin; Ko, Chih-Hung

    2012-01-01

    Social anxiety was compared between online and real-life interaction in a sample of 2,348 college students. Severity of social anxiety in both real-life and online interaction was tested for associations with depression, Internet addiction, Internet activity type (gaming versus chatting), and scores on Behavioral Inhibition System (BIS)/Behavioral Activation System (BAS) scales. The results showed that social anxiety was lower when interacting online than when interacting offline. Depression, Internet addiction, and high BIS and BAS scores were associated with high social anxiety. The social anxiety decreased more in online interaction among subjects with high social anxiety, depression, BIS, and BAS. This result suggests that the Internet has good potential as an alternative medium for delivering interventions for social anxiety. Further, the effect of BIS on social anxiety is decreased in online interaction. More attention should be paid for BIS when the treatment for social anxiety is delivered online.

  20. Self-disclosure through weblogs and perceptions of online and "real-life" friendships among female bloggers.

    Science.gov (United States)

    Bane, Cynthia M H; Cornish, Marilyn; Erspamer, Nicole; Kampman, Lia

    2010-04-01

    The current study examined female bloggers' perceptions of online and "real-life" same-sex friendships and examined relationships between self-disclosure through blogs and perceptions of the two types of friendships. Three hundred seven female bloggers (M age = 34.56 years) completed an online survey regarding friendship satisfaction and perceptions of intimacy-promoting interaction patterns in friendships. One hundred respondents' weblogs were analyzed for self-disclosure. Self-reported self-disclosure was positively correlated with number of online friendships and satisfaction with online friendships. Although participants reported having close online friends, they perceived real-life friendships as more likely than online friendships to possess intimacy-promoting interaction patterns. These perceptions did not differ as a function of self-disclosure through blogging, although bloggers who were categorized as higher in disclosure were more satisfied with online friendships than were bloggers who were categorized as lower in disclosure. These results suggest a relationship between self-disclosure through blogging and online relationship satisfaction among women in middle adulthood but that these women perceive real-life friendships as more likely to offer interaction patterns that foster intimacy.

  1. The Oral Language Process in Writing: A Real-Life Writing Session.

    Science.gov (United States)

    Shuy, Roger W.; Robinson, David G.

    1990-01-01

    Analyzes a real-life writing session involving a male executive in the construction business, his female secretary, and a male representing himself as a state official, working collaboratively to write a letter to a state official urging action on a long overdue claim. Discusses the quality of the drafts and the participants' roles. (KEH)

  2. REAL-LIFE ACTIVITIES: BOOSTING MY STUDENTS’ AWARENESS OF HONESTY IN CREATING GENRE

    Directory of Open Access Journals (Sweden)

    Rr. Dewi Wahyu Mustikasari

    2017-04-01

    Full Text Available My students was strugled to write genre without copypasting sentences or texts from the internet. On the other hand, it was a huge challange for me to teach five big writing classes. Each class consisted of 25-30 students who tended (mostly collecting unoriginal writing works. This paper discusses the real-life activities that can be used to enhance my students’ aweareness of honesty in creating genre. My students must write some genres namely recount, descriptive (optional, spoof (optional, procedure, hortatory (optional and analytical exposition (optional text. I also took some benefits of ICT to equip the learning process. Browsing and experiencing the menu of premierskills.britishcouncil.org were the real-life activities that explore their personal memories to be told as the recount text. Then they defined the feature of one of the menu of the previous website to be informed as the descriptive text. Furthermore, they wrote their personal funny experiences which were related to the Indonesian culture as the spoof text. The procedure text can be produced by exploring the daily activities in the pictures such as how to make a cup of tea/coffee, cook a sunny side-up egg, insert sim card into mobile phone, etc. Next, my students visited the tourism and public places in Salatiga, and they observed the strength and weekness of those places as the production of hortatory or analytical exposition text. The real-life activities were able to foster my students’ awareness of honesty. It was fantastic that my students were able to create the genre honestly.

  3. Can virtual reality exposure therapy gains be generalized to real-life? : A meta-analysis of studies applying behavioral assessments

    NARCIS (Netherlands)

    Morina, Nexhmedin; Ijntema, Hiske; Meyerbröker, Katharina; Emmelkamp, Paul M G

    2015-01-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials

  4. Can virtual reality exposure therapy gains be generalized to real life? A meta-analysis of studies applying behavioral assessments

    NARCIS (Netherlands)

    Morina, N.; Ijntema, H.; Meyerbröker, K.; Emmelkamp, P.M.G.

    2015-01-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials

  5. Social Anxiety in Online and Real-Life Interaction and Their Associated Factors

    Science.gov (United States)

    Yen, Ju-Yu; Yen, Cheng-Fang; Chen, Cheng-Sheng; Wang, Peng-Wei; Chang, Yi-Hsin

    2012-01-01

    Abstract Social anxiety was compared between online and real-life interaction in a sample of 2,348 college students. Severity of social anxiety in both real-life and online interaction was tested for associations with depression, Internet addiction, Internet activity type (gaming versus chatting), and scores on Behavioral Inhibition System (BIS)/Behavioral Activation System (BAS) scales. The results showed that social anxiety was lower when interacting online than when interacting offline. Depression, Internet addiction, and high BIS and BAS scores were associated with high social anxiety. The social anxiety decreased more in online interaction among subjects with high social anxiety, depression, BIS, and BAS. This result suggests that the Internet has good potential as an alternative medium for delivering interventions for social anxiety. Further, the effect of BIS on social anxiety is decreased in online interaction. More attention should be paid for BIS when the treatment for social anxiety is delivered online. PMID:22175853

  6. Online Game Player Personality and Real-life Need Fulfillment

    Directory of Open Access Journals (Sweden)

    Ching-I Teng

    2009-12-01

    Full Text Available This study investigates the relationship between personality and real-life need fulfillment of 114 online game adolescent players, who had an average of 14.86 years in age and a standard deviation of 1.40 years. Of the sample, 73.7% were male and 88.8% had a monthly income below US $90. Results indicate that openness negatively correlated to fulfillment of needs for achievement and affiliation. Conscientiousness positively correlated to fulfillment of needs for achievement, affiliation, autonomy, and dominance. Extraversion positively correlated to fulfillment of needs for affiliation and dominance.

  7. Associations among everyday stress, critical life events, and sexual problems.

    Science.gov (United States)

    Bodenmann, Guy; Ledermann, Thomas; Blattner, Denise; Galluzzo, Claudia

    2006-07-01

    This study addresses the question of how stress is linked to sexual problems among women and men in close relationships. Psychological symptoms, relationship quality, internal daily stress (i.e., originating within the couple such as conflicts, worry for the partner), external daily stress (i.e., stress arising outside the couple such as job stress, stressful relatives, and so forth), and critical life events were examined with regard to their association with different sexual problems. The results support the hypotheses that (1) there is an incremental effect of stress on sexual problems after controlling for psychological symptoms and relationship quality, and that (2) it is primarily internal daily stress and in some cases critical life events rather than external daily stress that are related to sexual problems, particularly hypoactive sexual desire in women and men, sexual aversion in women, vaginismus in women, and premature ejaculation in men. Our findings indicate that the treatment of these sexual problems should address relationship issues and include a focus on helping individuals improve their stress management skills within their couple relationship.

  8. A novel dataset for real-life evaluation of facial expression recognition methodologies

    NARCIS (Netherlands)

    Siddiqi, Muhammad Hameed; Ali, Maqbool; Idris, Muhammad; Banos Legran, Oresti; Lee, Sungyoung; Choo, Hyunseung

    2016-01-01

    One limitation seen among most of the previous methods is that they were evaluated under settings that are far from real-life scenarios. The reason is that the existing facial expression recognition (FER) datasets are mostly pose-based and assume a predefined setup. The expressions in these datasets

  9. Real-life data for the optimization of the geometric layout of an intersection

    NARCIS (Netherlands)

    Fleuren, S.T.G.; Lefeber, A.A.J.

    2016-01-01

    This document contains the data of ten real-life intersections. This data can be used for the optimization of the geometric layout of the intersection, e.g., optimizing the arrival lanes, departure lanes and lane markings at the intersection.

  10. Treated and Untreated Remission from Problem Drinking in Late Life: Post-Remission Functioning and Health-Related Quality of Life

    Science.gov (United States)

    Schutte, Kathleen K.; Brennan, Penny L.; Moos, Rudolf H.

    2009-01-01

    Objective To evaluate the post-remission status of older remitted problem drinkers who achieved stable remission without treatment. Method The post-remission drinking behavior, health-related functioning, life context, coping, and help-seeking of older, untreated (n = 330) and treated (n = 120) former problem drinkers who had been remitted for a minimum of six years were compared twice over the course of six-years to each other and to lifetime nonproblem drinkers (n = 232). Analyses considered the impact of severity of drinking problem history. Results Untreated remitters were more likely than treated remitters to continue to drink, exhibited fewer chronic health problems and less depressive symptomatology, and were less likely to smoke. Untreated remitters’ life contexts were somewhat more benign than those of treated ones, and they were less likely to describe a coping motive for drinking and engage in post-remission help-seeking. Although untreated remitters more closely resembled lifetime nonproblem drinkers than did treated remitters, both untreated and treated remitter groups exhibited worse health-related functioning, more financial and interpersonal stressors, and more post-remission help-seeking than did lifetime nonproblem drinkers. Conclusions Regardless of whether late-life remission was gained without or with treatment, prior drinking problems conveyed a legacy of health-related and life context deficits. PMID:18829184

  11. Creating Machinima (3D) and Real Life Videos in an ESP Classroom

    Science.gov (United States)

    Ochoa Alpala, Carol Anne; Ortíz García, William Ricardo

    2018-01-01

    This research paper reports on the development of oral presentation skills in a 3D virtual world called "Moviestorm" machinima, in contrast with real-life videos. In this way, the implementation of both types of videos sought to promote the improvement of oral communication skills, specifically oral presentations in a foreign language,…

  12. How 4 Colleges Take on Veterans' Issues, in Research and Real Life

    Science.gov (United States)

    Sander, Libby

    2012-01-01

    This article features four colleges and how they take on veterans' issues in research and real life. These colleges are (1) Syracuse University; (2) Purdue University; (3) University of Southern California; and (4) University of North Carolina at Chapel Hill. Last year Syracuse established the Institute for Veterans and Military Families to focus…

  13. Ambiguity and risk measures in the lab and students’ real-life borrowing behavior

    NARCIS (Netherlands)

    Fairley, Kim; Weitzel, Utz

    This study analyzes the external validity of experimentally elicited ambiguity aversion, likelihood insensitivity and risk aversion on real-life decision-making in the field of student loans. Our main finding is that ambiguity aversion, likelihood insensitivity and risk aversion are not related to

  14. Quality of bystander cardiopulmonary resuscitation during real-life out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Gyllenborg, Tore; Granfeldt, Asger; Lippert, Freddy

    2017-01-01

    BACKGROUND: Cardiopulmonary resuscitation (CPR) can increase survival in out-of-hospital cardiac arrest (OHCA). However, little is known about bystander CPR quality in real-life OHCA. AIM: To describe bystander CPR quality based on automated external defibrillator (AED) CPR process data during OH...

  15. A Tentative Organizational Schema for Decision-Making Problems.

    Science.gov (United States)

    Osborn, William C.; Goodman, Barbara Ettinger

    This report presents the results of research that examined widely diverse decision problems and attempted to specify their common behavior elements. To take into account the psychological complexity of most real-life decision problems, and to develop a tentative organization of decision behavior that will embrace the many, highly diverse types of…

  16. Adverse life events and emotional and behavioural problems in adolescence: the role of coping and emotion regulation.

    Science.gov (United States)

    Flouri, Eirini; Mavroveli, Stella

    2013-12-01

    We tested whether emotion regulation (cognitive reappraisal and expressive suppression) and coping (distraction, avoidance, support seeking and active coping) mediate or moderate the association between change in life stress (change in number of adverse life events) and change in adolescent problem behaviour. We used prospective and retrospective longitudinal data from a community sample. We measured change in problem behaviour as emotional and behavioural problems at Time 2 controlling for emotional and behavioural problems at Time 1, a year earlier. We measured change in life stress as life stress between Times 1 and 2, controlling for total previous life stress (before Time 1). Neither coping nor emotion regulation mediated the association between change in life stress and change in problem behaviour. Avoidance and expressive suppression were related to an increase in problem behaviour. Only cognitive reappraisal moderated the effect of increase in life stress on worsening of problem behaviour, suggesting that, as expected, cognitive reappraisal was a protective factor. In adolescents who reported they habitually reappraise, the association between change in life stress and change in emotional and behavioural problems was non-significant. Copyright © 2012 John Wiley & Sons, Ltd.

  17. The Home Care Crew Scheduling Problem: Preference-based visit clustering and temporal dependencies

    DEFF Research Database (Denmark)

    Rasmussen, Matias Sevel; Justesen, Tor Fog; Dohn, Anders Høeg

    2012-01-01

    In the Home Care Crew Scheduling Problem a staff of home carers has to be assigned a number of visits to patients’ homes, such that the overall service level is maximised. The problem is a generalisation of the vehicle routing problem with time windows. Required travel time between visits and time...... preference constraints. The algorithm is tested both on real-life problem instances and on generated test instances inspired by realistic settings. The use of the specialised branching scheme on real-life problems is novel. The visit clustering decreases run times significantly, and only gives a loss...... windows of the visits must be respected. The challenge when assigning visits to home carers lies in the existence of soft preference constraints and in temporal dependencies between the start times of visits.We model the problem as a set partitioning problem with side constraints and develop an exact...

  18. Using mathematics to solve real world problems: the role of enablers

    Science.gov (United States)

    Geiger, Vincent; Stillman, Gloria; Brown, Jill; Galbriath, Peter; Niss, Mogens

    2018-03-01

    The purpose of this article is to report on a newly funded research project in which we will investigate how secondary students apply mathematical modelling to effectively address real world situations. Through this study, we will identify factors, mathematical, cognitive, social and environmental that "enable" year 10/11 students to successfully begin the modelling process, that is, formulate and mathematise a real world problem. The 3-year study will take a design research approach in working intensively with six schools across two educational jurisdictions. It is anticipated that this research will generate new theoretical and practical insights into the role of "enablers" within the process of mathematisation, leading to the development of principles for the design and implementation for tasks that support students' development as modellers.

  19. Reperfusion Treatment for STEMI in Age Over 75 Years: Unsatisfactory Real-Life Practice

    Czech Academy of Sciences Publication Activity Database

    Monhart, Z.; Grünfeldová, H.; Zvárová, Jana; Janský, P.

    2010-01-01

    Roč. 122, č. 2 (2010), e69 ISSN 0009-7322. [World Congress of Cardiology . 16.06.2010-19.06.2010, Beijing] Institutional research plan: CEZ:AV0Z10300504 Keywords : cardiology * reperfusion treatment * real-life practice Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

  20. Disease spreading in real-life networks

    Science.gov (United States)

    Gallos, Lazaros; Argyrakis, Panos

    2002-08-01

    In recent years the scientific community has shown a vivid interest in the network structure and dynamics of real-life organized systems. Many such systems, covering an extremely wide range of applications, have been recently shown to exhibit scale-free character in their connectivity distribution, meaning that they obey a power law. Modeling of epidemics on lattices and small-world networks suffers from the presence of a critical infection threshold, above which the entire population is infected. For scale-free networks, the original assumption was that the formation of a giant cluster would lead to an epidemic spreading in the same way as in simpler networks. Here we show that modeling epidemics on a scale-free network can greatly improve the predictions on the rate and efficiency of spreading, as compared to lattice models and small-world networks. We also show that the dynamics of a disease are greatly influenced by the underlying population structure. The exact same model can describe a plethora of networks, such as social networks, virus spreading in the Web, rumor spreading, signal transmission etc.

  1. Importance of leadership in cardiac arrest situations: from simulation to real life and back.

    Science.gov (United States)

    Hunziker, Sabnina; Tschan, Franziska; Semmer, Norbert K; Marsch, Stephan

    2013-04-18

    The 2010 American Heart Association guidelines now recommend leadership training in Advanced Cardiac Life Support courses. In this review we provide a comprehensive summary of data derived from clinical studies that investigated the importance of leadership in cardiopulmonary resuscitation (CPR). Only a few, mostly observational, studies have been conducted under real-life conditions because of the high heterogeneity of the situations, difficulties in capturing the initial phase of CPR, and ethical issues. Well-controlled studies in the human simulator can fill existing gaps and provide important insights. High-fidelity video-assisted simulator studies from different research groups have shown that a prolonged process of teambuilding is associated with significant shortcomings in CPR, whereas effective leadership improves team performance. In addition, randomised controlled studies have provided evidence that medical students receiving leadership training subsequently showed improved CPR performance, which was sustained after a follow up of 4 months. In addition, leadership is influenced by gender and other factors such as emotional stress. Future studies are needed to investigate cultural differences and how findings from the simulator can be transferred to real-life situations.

  2. The Influence of Cognitive Abilities on Mathematical Problem Solving Performance

    Science.gov (United States)

    Bahar, Abdulkadir

    2013-01-01

    Problem solving has been a core theme in education for several decades. Educators and policy makers agree on the importance of the role of problem solving skills for school and real life success. A primary purpose of this study was to investigate the influence of cognitive abilities on mathematical problem solving performance of students. The…

  3. Coping and social problem solving correlates of asthma control and quality of life.

    Science.gov (United States)

    McCormick, Sean P; Nezu, Christine M; Nezu, Arthur M; Sherman, Michael; Davey, Adam; Collins, Bradley N

    2014-02-01

    In a sample of adults with asthma receiving care and medication in an outpatient pulmonary clinic, this study tested for statistical associations between social problem-solving styles, asthma control, and asthma-related quality of life. These variables were measured cross sectionally as a first step toward more systematic application of social problem-solving frameworks in asthma self-management training. Recruitment occurred during pulmonology clinic service hours. Forty-four adults with physician-confirmed diagnosis of asthma provided data including age, gender, height, weight, race, income, and comorbid conditions. The Asthma Control Questionnaire, the Mini Asthma Quality of Life Questionnaire (Short Form), and peak expiratory force measures offered multiple views of asthma health at the time of the study. Maladaptive coping (impulsive and careless problem-solving styles) based on transactional stress models of health were assessed with the Social Problem-Solving Inventory-Revised: Short Form. Controlling for variance associated with gender, age, and income, individuals reporting higher impulsive-careless scores exhibited significantly lower scores on asthma control (β = 0.70, p = 0.001, confidence interval (CI) [0.37-1.04]) and lower asthma-related quality of life (β = 0.79, p = 0.017, CI [0.15-1.42]). These findings suggest that specific maladaptive problem-solving styles may uniquely contribute to asthma health burdens. Because problem-solving coping strategies are both measureable and teachable, behavioral interventions aimed at facilitating adaptive coping and problem solving could positively affect patient's asthma management and quality of life.

  4. Modern social life and never-married women's health problems

    Directory of Open Access Journals (Sweden)

    Patrapan Tamdee

    2016-01-01

    Full Text Available This study explored the health problems of never-married women as they relate to modern social life. In-depth interviews were conducted with a purposive sample of 45 never-married women aged 30–50 working or living in Bangkok and having health problems. It was found that never-married women in this modern era have experienced a variety of illnesses, such as “office syndrome” symptoms, chronic illnesses, and psychological and psychosomatic symptoms. Their social life resulted from the response to the context of modernity and was made through careful thought and deliberation. Whichever choice of social life they make, the consequences may lead them to a state of illness, distress, anxiety, and paranoia. These choices involve work, living conditions/environments, and intimacy aspects of their modern social life. This is the result of procuring by “husky modernity” which seems to be merely a “husk” or superficial modernization and changes so rapidly, but there is no core and it is full of double standards of traditional and new norms that have mixed together and fight against each other. Supporting health-related knowledge and information exchange within the network coupled with experience sharing essential for living in the modern society will enable them to sensibly decide on a path to good health.

  5. Real-life effectiveness of smoking-cessation treatments in general practice clinics in Denmark. The Escape Smoke project

    DEFF Research Database (Denmark)

    Poulsen, Peter Bo; Spillemose, Heidi; Nielsen, Gerda

    2015-01-01

    BACKGROUND: The smoking prevalence has not decreased in the last years in Denmark. General practice (GP) offers smoking cessation (SC) treatment. Studies of real-life effectiveness of daily practice SC-activities from the GP-setting opposed to efficacy results from randomized clinical trials...... are few. The study aim was to evaluate the real-life effectiveness of SC-treatments for daily smokers among Danish GP-clinics. METHODS: In a multi-centre-based observational study design Danish GP-clinics with prior SC-activity recruited daily smokers motivated for quitting. As per usual clinical practice...

  6. Real-life memory and spatial navigation in patients with focal epilepsy: ecological validity of a virtual reality supermarket task.

    Science.gov (United States)

    Grewe, P; Lahr, D; Kohsik, A; Dyck, E; Markowitsch, H J; Bien, C G; Botsch, M; Piefke, M

    2014-02-01

    Ecological assessment and training of real-life cognitive functions such as visual-spatial abilities in patients with epilepsy remain challenging. Some studies have applied virtual reality (VR) paradigms, but external validity of VR programs has not sufficiently been proven. Patients with focal epilepsy (EG, n=14) accomplished an 8-day program in a VR supermarket, which consisted of learning and buying items on a shopping list. Performance of the EG was compared with that of healthy controls (HCG, n=19). A comprehensive neuropsychological examination was administered. Real-life performance was investigated in a real supermarket. Learning in the VR supermarket was significantly impaired in the EG on different VR measures. Delayed free recall of products did not differ between the EG and the HCG. Virtual reality scores were correlated with neuropsychological measures of visual-spatial cognition, subjective estimates of memory, and performance in the real supermarket. The data indicate that our VR approach allows for the assessment of real-life visual-spatial memory and cognition in patients with focal epilepsy. The multimodal, active, and complex VR paradigm may particularly enhance visual-spatial cognitive resources. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. Problems Related to the Abolition of Divided Real Estate Ownership

    Directory of Open Access Journals (Sweden)

    Dinsberga Jolanta

    2016-12-01

    Full Text Available Legal relationship between apartment owners in residential buildings and the land owners, that is, divided real estate ownership, was created in the Republic of Latvia in 1990, within the framework of the Land Reform, restoring property rights of the former owners or their heirs or privatising apartments in multi-apartment residential buildings. The existence of such legal relationship created different lease problems and restrictions on the property rights to the owners of both the building and the land. To abolish the legal relationship related to divided real estate ownership, the Ministry of Justice of the Republic of Latvia has developed a draft law Regarding the Abolition of Mandatory Divided Real Estate Ownership in Multi-Apartment Buildings (hereinafter referred to as Draft Law. Unfortunately, in the opinion of authors of this article, there are serious shortcomings to the Draft Law which must be corrected. The aim of the research is to identify the problematic issues by selecting and analysing the legislation on the abolition of the divided real estate ownership, which is related to the calculation of redemption price, payment method and consequences of non-payment, which are not regulated by the new Draft Law. The article reflects research on the determination and calculation of redemption price reglamented by the Draft Law and also analyses the Law of December 8, 1938, On the Abolition of Divided Real Estate Ownership and its practical implementation, which may significantly influence the redemption price and the method of its calculation; however, the mentioned law has been disregarded in developing the Draft Law. Thus the research has both theoretical and practical significance. For the research purposes general research methods, such as historical, analytical, inductive, deductive, logical-constructive and descriptive methods, are used. For the interpretation of legislation norms, grammatical, systemic, teleological and historical

  8. "It happened, what’s the problem?" and "A guide through the problem": A model for consideration of ecological issues in chemistry education

    Directory of Open Access Journals (Sweden)

    Korolija Jasminka N.

    2015-01-01

    Full Text Available In order to improve the ability for application of knowledge of chemistry (acquired in the existing educational system in real life the Model for Consideration of Ecological Issues was developed and applied in high school. The Model consists of the continuous text (“It Happened, What’s the Problem?” and the test with non-continuous text (“A Guide Through the Problem”, which are prepared for consideration of the problem of eutrophication. All results obtained (average achievement of 70.9±14.3 % showed that the application of the Model enabled: understanding of an ecological problem based on scientific representations of the term eutrophication given in the continuous text, realization that the pollution of our environment may be directly related to modern life, application of acquired knowledge of chemistry to observe and understand the cause and effect of eutrophication in our environment, to draw a scientific conclusion, and understanding the importance of science and technology discoveries for solving ecological problems. In addition, Model contributed to the development of student’s environmental literacy (ecological knowledge and cognitive skills, ability to think critically, and provided possibilities for classroom knowledge to become applicable in real life. [Projekat Ministarstva nauke Republike Srbije, br. 179048

  9. Effects of cooperative and problem-solving learning strategies on ...

    African Journals Online (AJOL)

    Learning is internalised faster and better when students are given opportunity to interact with one another in small groups; when topics are structured to solve real life problems, studying becomes fun and learning is facilitated and internalised; students learn better when a problem is used as a starting point for new ...

  10. Relating the Learned Knowledge and Acquired Skills to Real Life: Function Sample

    Science.gov (United States)

    Albayrak, Mustafa; Yazici, Nurullah; Simsek, Mertkan

    2017-01-01

    Considering that Mathematics is a multidimensional problem-solving method that can be effective in all areas of cultural life, it is of great importance because of its contribution to other sciences such as physical and social sciences. It is known that the basic concepts of mathematics, which can also be expressed as a way of life, have helped to…

  11. Programming and Tuning a Quantum Annealing Device to Solve Real World Problems

    Science.gov (United States)

    Perdomo-Ortiz, Alejandro; O'Gorman, Bryan; Fluegemann, Joseph; Smelyanskiy, Vadim

    2015-03-01

    Solving real-world applications with quantum algorithms requires overcoming several challenges, ranging from translating the computational problem at hand to the quantum-machine language to tuning parameters of the quantum algorithm that have a significant impact on the performance of the device. In this talk, we discuss these challenges, strategies developed to enhance performance, and also a more efficient implementation of several applications. Although we will focus on applications of interest to NASA's Quantum Artificial Intelligence Laboratory, the methods and concepts presented here apply to a broader family of hard discrete optimization problems, including those that occur in many machine-learning algorithms.

  12. Excel 2016 for biological and life sciences statistics a guide to solving practical problems

    CERN Document Server

    Quirk, Thomas J; Horton, Howard F

    2016-01-01

    This book is a step-by-step exercise-driven guide for students and practitioners who need to master Excel to solve practical biological and life science problems. If understanding statistics isn’t your strongest suit, you are not especially mathematically-inclined, or if you are wary of computers, this is the right book for you. Excel is an effective learning tool for quantitative analyses in biological and life sciences courses. Its powerful computational ability and graphical functions make learning statistics much easier than in years past. However, Excel 2016 for Biological and Life Sciences Statistics: A Guide to Solving Practical Problems is the first book to capitalize on these improvements by teaching students and managers how to apply Excel 2016 to statistical techniques necessary in their courses and work. Each chapter explains statistical formulas and directs the reader to use Excel commands to solve specific, easy-to-understand biological and life science problems. Practice problems are provided...

  13. Emotional Creativity and Real-Life Involvement in Different Types of Creative Leisure Activities

    Science.gov (United States)

    Trnka, Radek; Zahradnik, Martin; Kuška, Martin

    2016-01-01

    The role of emotional creativity in practicing creative leisure activities and in the preference of college majors remains unknown. This study aims to explore how emotional creativity measured by the Emotional Creativity Inventory (ECI; Averill, 1999) is interrelated with the real-life involvement in different types of specific creative leisure…

  14. The Orienteering Problem under Uncertainty Stochastic Programming and Robust Optimization compared

    NARCIS (Netherlands)

    L. Evers (Lanah); K.M. Glorie (Kristiaan); S. van der Ster (Suzanne); A.I. Barros (Ana); H. Monsuur (Herman)

    2012-01-01

    textabstractThe Orienteering Problem (OP) is a generalization of the well-known traveling salesman problem and has many interesting applications in logistics, tourism and defense. To reflect real-life situations, we focus on an uncertain variant of the OP. Two main approaches that deal with

  15. Can virtual reality exposure therapy gains be generalized to real-life? A meta-analysis of studies applying behavioral assessments.

    Science.gov (United States)

    Morina, Nexhmedin; Ijntema, Hiske; Meyerbröker, Katharina; Emmelkamp, Paul M G

    2015-11-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials applying VRET to specific phobias and measuring treatment outcome by means of behavioral laboratory tests or recordings of behavioral activities in real-life. Data sources were searches of databases (Medline, PsycInfo, and Cochrane). We included in total 14 clinical trials on specific phobias. Results revealed that patients undergoing VRET did significantly better on behavioral assessments following treatment than before treatment, with an aggregated uncontrolled effect size of g = 1.23. Furthermore, patients undergoing VRET performed better on behavioral assessments at post-treatment than patients on wait-list (g = 1.41). Additionally, results of behavioral assessment at post-treatment and at follow-up revealed no significant differences between VRET and exposure in vivo (g = -0.09 and 0.53, respectively). Finally, behavioral measurement effect sizes were similar to those calculated from self-report measures. The findings demonstrate that VRET can produce significant behavior change in real-life situations and support its application in treating specific phobias. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. An Improved Real-Coded Population-Based Extremal Optimization Method for Continuous Unconstrained Optimization Problems

    Directory of Open Access Journals (Sweden)

    Guo-Qiang Zeng

    2014-01-01

    Full Text Available As a novel evolutionary optimization method, extremal optimization (EO has been successfully applied to a variety of combinatorial optimization problems. However, the applications of EO in continuous optimization problems are relatively rare. This paper proposes an improved real-coded population-based EO method (IRPEO for continuous unconstrained optimization problems. The key operations of IRPEO include generation of real-coded random initial population, evaluation of individual and population fitness, selection of bad elements according to power-law probability distribution, generation of new population based on uniform random mutation, and updating the population by accepting the new population unconditionally. The experimental results on 10 benchmark test functions with the dimension N=30 have shown that IRPEO is competitive or even better than the recently reported various genetic algorithm (GA versions with different mutation operations in terms of simplicity, effectiveness, and efficiency. Furthermore, the superiority of IRPEO to other evolutionary algorithms such as original population-based EO, particle swarm optimization (PSO, and the hybrid PSO-EO is also demonstrated by the experimental results on some benchmark functions.

  17. Exploring the relationship between quality of life and mental health problems in children: implications for measurement and practice.

    Science.gov (United States)

    Sharpe, Helen; Patalay, Praveetha; Fink, Elian; Vostanis, Panos; Deighton, Jessica; Wolpert, Miranda

    2016-06-01

    Quality of life is typically reduced in children with mental health problems. Understanding the relationship between quality of life and mental health problems and the factors that moderate this association is a pressing priority. This was a cross-sectional study involving 45,398 children aged 8-13 years from 880 schools in England. Self-reported quality of life was assessed using nine items from the KIDSCREEN-10 and mental health was assessed using the Me and My School Questionnaire. Demographic information (gender, age, ethnicity, socio-economic status) was also recorded. Quality of life was highest in children with no problems and lowest in children with both internalising and externalising problems. There was indication that quality of life may be reduced in children with internalising problems compared with externalising problems. Approximately 12 % children with mental health problems reported high quality of life. The link between mental health and quality of life was moderated by gender and age but not by socio-economic status or ethnicity. This study supports previous work showing mental health and quality of life are related but not synonymous. The findings have implications for measuring quality of life in child mental health settings and the need for approaches to support children with mental health problems that are at particular risk of poor quality of life.

  18. Development of a diagnostic decision tree for obstructive pulmonary diseases based on real-life data

    Directory of Open Access Journals (Sweden)

    Esther I. Metting

    2016-01-01

    Full Text Available The aim of this study was to develop and explore the diagnostic accuracy of a decision tree derived from a large real-life primary care population. Data from 9297 primary care patients (45% male, mean age 53±17 years with suspicion of an obstructive pulmonary disease was derived from an asthma/chronic obstructive pulmonary disease (COPD service where patients were assessed using spirometry, the Asthma Control Questionnaire, the Clinical COPD Questionnaire, history data and medication use. All patients were diagnosed through the Internet by a pulmonologist. The Chi-squared Automatic Interaction Detection method was used to build the decision tree. The tree was externally validated in another real-life primary care population (n=3215. Our tree correctly diagnosed 79% of the asthma patients, 85% of the COPD patients and 32% of the asthma–COPD overlap syndrome (ACOS patients. External validation showed a comparable pattern (correct: asthma 78%, COPD 83%, ACOS 24%. Our decision tree is considered to be promising because it was based on real-life primary care patients with a specialist's diagnosis. In most patients the diagnosis could be correctly predicted. Predicting ACOS, however, remained a challenge. The total decision tree can be implemented in computer-assisted diagnostic systems for individual patients. A simplified version of this tree can be used in daily clinical practice as a desk tool.

  19. Development of a diagnostic decision tree for obstructive pulmonary diseases based on real-life data

    Science.gov (United States)

    in ’t Veen, Johannes C.C.M.; Dekhuijzen, P.N. Richard; van Heijst, Ellen; Kocks, Janwillem W.H.; Muilwijk-Kroes, Jacqueline B.; Chavannes, Niels H.; van der Molen, Thys

    2016-01-01

    The aim of this study was to develop and explore the diagnostic accuracy of a decision tree derived from a large real-life primary care population. Data from 9297 primary care patients (45% male, mean age 53±17 years) with suspicion of an obstructive pulmonary disease was derived from an asthma/chronic obstructive pulmonary disease (COPD) service where patients were assessed using spirometry, the Asthma Control Questionnaire, the Clinical COPD Questionnaire, history data and medication use. All patients were diagnosed through the Internet by a pulmonologist. The Chi-squared Automatic Interaction Detection method was used to build the decision tree. The tree was externally validated in another real-life primary care population (n=3215). Our tree correctly diagnosed 79% of the asthma patients, 85% of the COPD patients and 32% of the asthma–COPD overlap syndrome (ACOS) patients. External validation showed a comparable pattern (correct: asthma 78%, COPD 83%, ACOS 24%). Our decision tree is considered to be promising because it was based on real-life primary care patients with a specialist's diagnosis. In most patients the diagnosis could be correctly predicted. Predicting ACOS, however, remained a challenge. The total decision tree can be implemented in computer-assisted diagnostic systems for individual patients. A simplified version of this tree can be used in daily clinical practice as a desk tool. PMID:27730177

  20. Quality of life of people with mental health problems: a synthesis of qualitative research.

    Science.gov (United States)

    Connell, Janice; Brazier, John; O'Cathain, Alicia; Lloyd-Jones, Myfanwy; Paisley, Suzy

    2012-11-22

    To identify the domains of quality of life important to people with mental health problems. A systematic review of qualitative research undertaken with people with mental health problems using a framework synthesis. We identified six domains: well-being and ill-being; control, autonomy and choice; self-perception; belonging; activity; and hope and hopelessness. Firstly, symptoms or 'ill-being' were an intrinsic aspect of quality of life for people with severe mental health problems. Additionally, a good quality of life was characterised by the feeling of being in control (particularly of distressing symptoms), autonomy and choice; a positive self-image; a sense of belonging; engagement in meaningful and enjoyable activities; and feelings of hope and optimism. Conversely, a poor quality life, often experienced by those with severe mental health difficulties, was characterized by feelings of distress; lack of control, choice and autonomy; low self-esteem and confidence; a sense of not being part of society; diminished activity; and a sense of hopelessness and demoralization. Generic measures fail to address the complexity of quality of life measurement and the broad range of domains important to people with mental health problems.

  1. Quality of life of people with mental health problems: a synthesis of qualitative research

    Directory of Open Access Journals (Sweden)

    Connell Janice

    2012-11-01

    Full Text Available Abstract Purpose To identify the domains of quality of life important to people with mental health problems. Method A systematic review of qualitative research undertaken with people with mental health problems using a framework synthesis. Results We identified six domains: well-being and ill-being; control, autonomy and choice; self-perception; belonging; activity; and hope and hopelessness. Firstly, symptoms or ‘ill-being’ were an intrinsic aspect of quality of life for people with severe mental health problems. Additionally, a good quality of life was characterised by the feeling of being in control (particularly of distressing symptoms, autonomy and choice; a positive self-image; a sense of belonging; engagement in meaningful and enjoyable activities; and feelings of hope and optimism. Conversely, a poor quality life, often experienced by those with severe mental health difficulties, was characterized by feelings of distress; lack of control, choice and autonomy; low self-esteem and confidence; a sense of not being part of society; diminished activity; and a sense of hopelessness and demoralization. Conclusions Generic measures fail to address the complexity of quality of life measurement and the broad range of domains important to people with mental health problems.

  2. Measurement of Walking Ground Reactions in Real-Life Environments: A Systematic Review of Techniques and Technologies.

    Science.gov (United States)

    Shahabpoor, Erfan; Pavic, Aleksandar

    2017-09-12

    Monitoring natural human gait in real-life environments is essential in many applications, including quantification of disease progression, monitoring the effects of treatment, and monitoring alteration of performance biomarkers in professional sports. Nevertheless, developing reliable and practical techniques and technologies necessary for continuous real-life monitoring of gait is still an open challenge. A systematic review of English-language articles from scientific databases including Scopus, ScienceDirect, Pubmed, IEEE Xplore, EBSCO and MEDLINE were carried out to analyse the 'accuracy' and 'practicality' of the current techniques and technologies for quantitative measurement of the tri-axial walking ground reactions outside the laboratory environment, and to highlight their strengths and shortcomings. In total, 679 relevant abstracts were identified, 54 full-text papers were included in the paper and the quantitative results of 17 papers were used for meta-analysis and comparison. Three classes of methods were reviewed: (1) methods based on measured kinematic data; (2) methods based on measured plantar pressure; and (3) methods based on direct measurement of ground reactions. It was found that all three classes of methods have competitive accuracy levels with methods based on direct measurement of the ground reactions showing highest accuracy while being least practical for long-term real-life measurement. On the other hand, methods that estimate ground reactions using measured body kinematics show highest practicality of the three classes of methods reviewed. Among the most prominent technical and technological challenges are: (1) reducing the size and price of tri-axial load-cells; (2) improving the accuracy of orientation measurement using IMUs; (3) minimizing the number and optimizing the location of required IMUs for kinematic measurement; (4) increasing the durability of pressure insole sensors, and (5) enhancing the robustness and versatility of the

  3. Measurement of Walking Ground Reactions in Real-Life Environments: A Systematic Review of Techniques and Technologies

    Directory of Open Access Journals (Sweden)

    Erfan Shahabpoor

    2017-09-01

    Full Text Available Monitoring natural human gait in real-life environments is essential in many applications, including quantification of disease progression, monitoring the effects of treatment, and monitoring alteration of performance biomarkers in professional sports. Nevertheless, developing reliable and practical techniques and technologies necessary for continuous real-life monitoring of gait is still an open challenge. A systematic review of English-language articles from scientific databases including Scopus, ScienceDirect, Pubmed, IEEE Xplore, EBSCO and MEDLINE were carried out to analyse the ‘accuracy’ and ‘practicality’ of the current techniques and technologies for quantitative measurement of the tri-axial walking ground reactions outside the laboratory environment, and to highlight their strengths and shortcomings. In total, 679 relevant abstracts were identified, 54 full-text papers were included in the paper and the quantitative results of 17 papers were used for meta-analysis and comparison. Three classes of methods were reviewed: (1 methods based on measured kinematic data; (2 methods based on measured plantar pressure; and (3 methods based on direct measurement of ground reactions. It was found that all three classes of methods have competitive accuracy levels with methods based on direct measurement of the ground reactions showing highest accuracy while being least practical for long-term real-life measurement. On the other hand, methods that estimate ground reactions using measured body kinematics show highest practicality of the three classes of methods reviewed. Among the most prominent technical and technological challenges are: (1 reducing the size and price of tri-axial load-cells; (2 improving the accuracy of orientation measurement using IMUs; (3 minimizing the number and optimizing the location of required IMUs for kinematic measurement; (4 increasing the durability of pressure insole sensors, and (5 enhancing the robustness and

  4. Engineers and the Web: An analysis of real life gaps in information usage

    NARCIS (Netherlands)

    Kraaijenbrink, Jeroen

    2007-01-01

    Engineers face a wide range of gaps when trying to identify, acquire, and utilize information from the Web. To be able to avoid creating such gaps, it is essential to understand them in detail. This paper reports the results of a study of the real life gaps in information usage processes of 17

  5. A framework for dynamic rescheduling problems

    DEFF Research Database (Denmark)

    Larsen, Rune; Pranzo, Marco

    2018-01-01

    . Extensive tests are carried out for the job shop problem, and we demonstrate that the framework can be used to ascertain the benefit of using rescheduling over static methods, decide between rescheduling policies, and finally we show that it can be applied in real-life applications due to a low time...

  6. Virginia Tech's Center For Real Life Kitchen Design Is A Success!

    OpenAIRE

    Todd, Jane Anne

    2003-01-01

    Explore Your Dream Kitchen, a two-day workshop offered in Virginia Tech's Center for Real Life Kitchen Design, will be offered twice in May to participants who want to learn about planning and designing a kitchen that really meets their needs. Attendees explore and experience kitchens with a wide variety of designs, products, materials, and technologies during this fun and interactive course. Participants are asked to bring plans, ideas, and questions about their homes and kitchens as everyon...

  7. Uncertain multi-objective multi-product solid transportation problems

    Indian Academy of Sciences (India)

    Deepika Rani

    ... made more effective by incorporating some other factors, which make it useful in real life .... For the above problem to be balanced it should satisfy: ..... Now, first step is to balance the ...... In this work, the fuzzy optimal compromise solution is.

  8. Sleep Characteristics, Sleep Problems, and Associations to Quality of Life among Psychotherapists.

    Science.gov (United States)

    Schlarb, Angelika A; Reis, Dorota; Schröder, Annette

    2012-01-01

    Sleep problems, especially insomnia, are a common complaint among adults. International studies have shown prevalence rates between 4.7 and 36.2% for sleep difficulties in general, whereas 13.1-28.1% report insomnia symptoms. Sleep problems are associated with lower social and academic performance and can have a severe impact on psychological and physical health. Psychotherapists are suppliers within the public health system. The goal of this study was to outline sleep characteristics, prevalence of sleep problems, insomnia, and associations of quality of life among psychotherapists. A total of 774 psychotherapists (74.7% women; mean age 46 years) participated in the study. Sleep characteristics, sleep problems, well-being, life satisfaction and workload, as well as specific job demands, were assessed via a questionnaire. Analyses revealed that more than 4.2% of the surveyed psychotherapists have difficulties falling asleep, 12.7% often wake up in the night, and 26.6% feel tired, and 3.4% think that their interrupted sleep affects work performance. About 44.1% of them suffer from symptoms of insomnia. Path models showed that insomnia is significantly related to well-being and life satisfaction.

  9. Sleep Characteristics, Sleep Problems, and Associations to Quality of Life among Psychotherapists

    Directory of Open Access Journals (Sweden)

    Angelika A. Schlarb

    2012-01-01

    Full Text Available Sleep problems, especially insomnia, are a common complaint among adults. International studies have shown prevalence rates between 4.7 and 36.2% for sleep difficulties in general, whereas 13.1–28.1% report insomnia symptoms. Sleep problems are associated with lower social and academic performance and can have a severe impact on psychological and physical health. Psychotherapists are suppliers within the public health system. The goal of this study was to outline sleep characteristics, prevalence of sleep problems, insomnia, and associations of quality of life among psychotherapists. A total of 774 psychotherapists (74.7% women; mean age 46 years participated in the study. Sleep characteristics, sleep problems, well-being, life satisfaction and workload, as well as specific job demands, were assessed via a questionnaire. Analyses revealed that more than 4.2% of the surveyed psychotherapists have difficulties falling asleep, 12.7% often wake up in the night, and 26.6% feel tired, and 3.4% think that their interrupted sleep affects work performance. About 44.1% of them suffer from symptoms of insomnia. Path models showed that insomnia is significantly related to well-being and life satisfaction.

  10. The Orienteering Problem under Uncertainty Stochastic Programming and Robust Optimization compared

    NARCIS (Netherlands)

    Evers, L.; Glorie, K.; Ster, S. van der; Barros, A.I.; Monsuur, H.

    2012-01-01

    The Orienteering Problem (OP) is a generalization of the well-known traveling salesman problem and has many interesting applications in logistics, tourism and defense. To reflect real-life situations, we focus on an uncertain variant of the OP. Two main approaches that deal with optimization under

  11. The sign problem in real-time path integral simulations: Using the cumulant action to implement multilevel blocking

    International Nuclear Information System (INIS)

    Mak, C. H.

    2009-01-01

    A practical method to tackle the sign problem in real-time path integral simulations is proposed based on the multilevel blocking idea. The formulation is made possible by using a cumulant expansion of the action, which in addition to addressing the sign problem, provides an unbiased estimator for the action from a statistically noisy sample of real-time paths. The cumulant formulation also allows the analytical gradients of the action to be computed with little extra computational effort, and it can easily be implemented in a massively parallel environment.

  12. Images of eyes enhance investments in a real-life public good.

    Directory of Open Access Journals (Sweden)

    Damien Francey

    Full Text Available A key issue in cooperation research is to determine the conditions under which individuals invest in a public good. Here, we tested whether cues of being watched increase investments in an anonymous public good situation in real life. We examined whether individuals would invest more by removing experimentally placed garbage (paper and plastic bottles from bus stop benches in Geneva in the presence of images of eyes compared to controls (images of flowers. We provided separate bins for each of both types of garbage to investigate whether individuals would deposit more items into the appropriate bin in the presence of eyes. The treatment had no effect on the likelihood that individuals present at the bus stop would remove garbage. However, those individuals that engaged in garbage clearing, and were thus likely affected by the treatment, invested more time to do so in the presence of eyes. Images of eyes had a direct effect on behaviour, rather than merely enhancing attention towards a symbolic sign requesting removal of garbage. These findings show that simple images of eyes can trigger reputational effects that significantly enhance on non-monetary investments in anonymous public goods under real life conditions. We discuss our results in the light of previous findings and suggest that human social behaviour may often be shaped by relatively simple and potentially unconscious mechanisms instead of very complex cognitive capacities.

  13. Everyday problem solving across the adult life span: solution diversity and efficacy

    Science.gov (United States)

    Mienaltowski, Andrew

    2013-01-01

    Everyday problem solving involves examining the solutions that individuals generate when faced with problems that take place in their everyday experiences. Problems can range from medication adherence and meal preparation to disagreeing with a physician over a recommended medical procedure or compromising with extended family members over where to host Thanksgiving dinner. Across the life span, research has demonstrated divergent patterns of change in performance based on the type of everyday problems used as well as based on the way that problem-solving efficacy is operationally defined. Advancing age is associated with worsening performance when tasks involve single-solution or fluency-based definitions of effectiveness. However, when efficacy is defined in terms of the diversity of strategies used, as well as by the social and emotional impact of solution choice on the individual, performance is remarkably stable and sometimes even improves in the latter half of life. This article discusses how both of these approaches to everyday problem solving inform research on the influence that aging has on everyday functioning. PMID:22023569

  14. Control of asthma in real life: still a valuable goal?

    Directory of Open Access Journals (Sweden)

    Andriana I. Papaioannou

    2015-06-01

    Full Text Available Although studies show that control of asthma can be achieved in the majority of patients, surveys repeatedly show that this is not the case in real life. Important measures to implement in order to achieve asthma control are trained healthcare professionals, a good patient–doctor relationship, patient education, avoidance of exposure to triggers, personalised management and adherence to treatment. These measures help the majority of asthma patients but have not yet been widely implemented and there should be a concerted action for their implementation. Moreover, further and focused research is needed in severe/refractory asthma.

  15. Technical life cycle of real estates

    OpenAIRE

    Taina Koskelo

    2001-01-01

    Real estate business is developing fast. Development needs are challenging because of interdiciplinariness and diverseness of the branch. The main mission of real estate business is to provide premises for its customers. Designers are planning the buildings, contractors are building them and owners are supplying premises for users. During the use the real estate market needs different kinds of facilitating services directed to users or owner of buildings. Facilities Management services (FM) c...

  16. Chronic urticaria in the real-life clinical practice setting in Sweden, Norway and Denmark

    DEFF Research Database (Denmark)

    Thomsen, S F; Pritzier, E C; Anderson, C D

    2017-01-01

    ]; chronic urticaria quality of life questionnaire [CU-Q2 oL; Danish patients only]) and work productivity and activity impairment (WPAI) scores were also assessed. RESULTS: Overall, 158 CU patients from seven centres in Denmark (n = 80), Norway (n = 50) and Sweden (n = 28) were included in this baseline......BACKGROUND: Chronic urticaria (CU) is characterized by the recurrence of itchy hives and/or angioedema for more than 6 weeks. AWARE (A World-wide Antihistamine-Refractory Chronic Urticaria Patient Evaluation) is a multinational study designed to document the real-life treatment situation, burden...... (>2 months) that is refractory to H1-antihistamines. Baseline patient characteristics, disease activity (urticaria control test [UCT]), pharmacological treatment, comorbidities and healthcare usage were documented by the treating physician. Quality of life (QoL; dermatology life quality index [DLQI...

  17. Internally controlled, generic real-time PCR for quantification and multiplex real-time PCR with serotype-specific probes for serotyping of dengue virus infections

    NARCIS (Netherlands)

    Menting, Sandra; Thai, Khoa T. D.; Nga, Tran T. T.; Phuong, Hoang L.; Klatser, Paul; Wolthers, Katja C.; Binh, Tran Q.; de Vries, Peter J.; Beld, Marcel

    2011-01-01

    Dengue has become a global public health problem and a sensitive diagnostic test for early phase detection can be life saving. An internally controlled, generic real-time PCR was developed and validated by testing serial dilutions of a DENV positive control RNA in the presence of a fixed amount of

  18. Real Time Systems

    DEFF Research Database (Denmark)

    Christensen, Knud Smed

    2000-01-01

    Describes fundamentals of parallel programming and a kernel for that. Describes methods for modelling and checking parallel problems. Real time problems.......Describes fundamentals of parallel programming and a kernel for that. Describes methods for modelling and checking parallel problems. Real time problems....

  19. Spouses of older adults with late-life drinking problems: health, family, and social functioning.

    Science.gov (United States)

    Moos, Rudolf H; Brennan, Penny L; Schutte, Kathleen K; Moos, Bernice S

    2010-07-01

    This study focuses on the health, family, and social functioning of spouses of late-life remitted and continuing problem drinkers, and on predictors of spouses' alcohol-related functioning and depressive symptoms. Three groups of spouses were compared at baseline and a 10-year follow-up: (a) spouses (n = 73) of older adults who had no drinking problems at baseline or follow-up, (b) spouses (n = 25) of older adults who had drinking problems at baseline but not follow-up, and (c) spouses (n = 69) of older adults who had drinking problems at both baseline and follow-up. At each contact point, spouses completed an inventory that assessed their alcohol-related, health, family, and social functioning. At baseline, compared with spouses of problem-free individuals, spouses of older adults whose drinking problems later remitted reported more alcohol consumption, poorer health, more depressive symptoms, and less involvement in domestic tasks and social and religious activities. At the 10-year follow-up, spouses of remitted problem drinkers were comparable to spouses of problem-free individuals, but spouses of continuing problem drinkers consumed more alcohol, incurred more alcohol-related consequences, and had friends who approved more of drinking. Overall, spouses whose friends approved more of drinking and whose partners consumed more alcohol and had drinking problems were likely to consume more alcohol and to have drinking problems themselves. Spouses of older adults whose late-life drinking problems remit can attain normal functioning; however, spouses of older adults with continuing late-life drinking problems experience some ongoing deficits.

  20. Spouses of Older Adults With Late-Life Drinking Problems: Health, Family, and Social Functioning*

    Science.gov (United States)

    Moos, Rudolf H.; Brennan, Penny L.; Schutte, Kathleen K.; Moos, Bernice S.

    2010-01-01

    Objective: This study focuses on the health, family, and social functioning of spouses of late-life remitted and continuing problem drinkers, and on predictors of spouses' alcohol-related functioning and depressive symptoms. Method: Three groups of spouses were compared at baseline and a 10-year follow-up: (a) spouses (n = 73) of older adults who had no drinking problems at baseline or follow-up, (b) spouses (n = 25) of older adults who had drinking problems at baseline but not follow-up, and (c) spouses (n = 69) of older adults who had drinking problems at both baseline and follow-up. At each contact point, spouses completed an inventory that assessed their alcohol-related, health, family, and social functioning. Results: At baseline, compared with spouses of problem-free individuals, spouses of older adults whose drinking problems later remitted reported more alcohol consumption, poorer health, more depressive symptoms, and less involvement in domestic tasks and social and religious activities. At the 10-year follow-up, spouses of remitted problem drinkers were comparable to spouses of problem-free individuals, but spouses of continuing problem drinkers consumed more alcohol, incurred more alcohol-related consequences, and had friends who approved more of drinking. Overall, spouses whose friends approved more of drinking and whose partners consumed more alcohol and had drinking problems were likely to consume more alcohol and to have drinking problems themselves. Conclusions: Spouses of older adults whose late-life drinking problems remit can attain normal functioning; however, spouses of older adults with continuing late-life drinking problems experience some ongoing deficits. PMID:20553658

  1. Life Satisfaction among High School Students with Social, Emotional, and Behavioral Problems

    Science.gov (United States)

    State, Talida M.; Kern, Lee

    2017-01-01

    Over the last decade, there has been increased interest in measuring life satisfaction among children and adolescents as an indicator of broad well-being and happiness. Although limited, existing research with students with social, emotional, and behavioral (SEB) problems indicates they experience lower life satisfaction compared with their…

  2. Health behaviour changes and onset of chronic health problems in later life

    Directory of Open Access Journals (Sweden)

    Marijke Veenstra

    2012-11-01

    Full Text Available Objectives: To assess five-year changes in health behaviours in later life and associations with onset of chronic health problems. The results may inform policy and interventions to promote healthy life years in ageing populations.Methods: Data are derived from the Norwegian study on Life-course, Ageing and Generation (NorLAG, a five-year (2002-2007 panel survey comprising a nation wide community sample. The present analyses include a sample of 1,019 respondents aged 60 years and older. Five-year changes in smoking, alcohol use, physical exercise and Body Mass Index (BMI are assessed according to prevalent and incident chronic health problems. Multivariate logistic analyses of “healthy” behavioural changes are conducted.Results: A total of 453 respondents (45% reported at least one chronic condition and 13% (N=133 reported onset of chronic conditions in the course of the past five years. Over a five-year period, there was an overall reduction in smoking rates and a decrease in regular physical activity. Alcohol consumption in older people slightly increased over time, but the incidence of chronic health problems tended to reduce alcohol intake. Older persons experiencing chronic health problems were less likely to initiate physical activity.Conclusions: The results provide limited support for the assumption that the onset of a chronic health condition triggers improved health behaviours. This suggests that the health care system could do more in targeting a potential “window of opportunity” for individuals to adopt new healthy behaviours in later life.

  3. Effect on marital satisfaction and life skills training in problem-solving styles housewives in Iran

    OpenAIRE

    Javadi Z.; Khanzadeh A.; Mousavi V.; Golandam A. K.

    2012-01-01

    Background and objective: Family is the most important and suitable system to resolve physical, psychological, and spiritual requirements of human being. Today, In spite of some cultural shifts and life style changes, many of the individuals, encountering life problems lack the basic and required abilities which result in family dissatisfaction and inability due to marital life's stresses that create problems and significant challenges in family system. For this reason,a better and more effec...

  4. Long-term Course of Alzheimer Disease in Patients Treated According to the Dutch Dementia Guideline at a Memory Clinic A "Real-Life" Study

    NARCIS (Netherlands)

    Droogsma, Erika; van Asselt, Dieneke; van Steijn, Jolanda; Diekhuis, Marjolein; Veeger, Nic; De Deyn, Peter P.

    2016-01-01

    Introduction:There is little knowledge of the long-term course of Alzheimer disease (AD) in light of current pharmacological and nonpharmacological interventions provided in a real-life setting.Methods:The Frisian Alzheimer's Disease Cohort study is a real-life study of the course of AD in patients

  5. Metacognition in Real Life Situations and Study Skills and Habits: Two Types of Processes

    Science.gov (United States)

    Al-Hilawani, Yasser A.

    2016-01-01

    The relationship between metacognition in real life situations and study skills and habits was examined using a sample of college students. Results showed no significant relationship between these two variables nor was there a significant relationship between study skills and reaction time as measured on the metacognitive test. However, there was…

  6. Moral Emotions and Moral Judgments in Children's Narratives: Comparing Real-Life and Hypothetical Transgressions

    Science.gov (United States)

    Gutzwiller-Helfenfinger, Eveline; Gasser, Luciano; Malti, Tina

    2010-01-01

    How children make meaning of their own social experiences in situations involving moral issues is central to their subsequent affective and cognitive moral learning. Our study of young children's narratives describing their interpersonal conflicts shows that the emotions and judgments constructed in the course of these real-life narratives differ…

  7. Contextualizing Performances: Comparing Performances during TOEFL iBT™ and Real-Life Academic Speaking Activities

    Science.gov (United States)

    Brooks, Lindsay; Swain, Merrill

    2014-01-01

    In this study we compare test takers' performance on the Speaking section of the TOEFL iBT™and their performances during their real-life academic studies. Thirty international graduate students from mixed language backgrounds in two different disciplines (Sciences and Social Sciences) responded to two independent and four integrated speaking tasks…

  8. A life course perspective on mental health problems, employment, and work outcomes

    NARCIS (Netherlands)

    Veldman, Karin; Reijneveld, Sijmen A; Verhulst, Frank C; Ortiz, Josue Almansa; Bültmann, Ute

    Objectives Little is known about how employment and work outcomes among young adults are influenced by their life-course history of mental health problems. Therefore, the aims of this study were to (i) identify trajectories of mental health problems from childhood to young adulthood and (ii)

  9. Math word problems for dummies

    CERN Document Server

    Sterling, Mary Jane

    2008-01-01

    Covers percentages, probability, proportions, and moreGet a grip on all types of word problems by applying them to real lifeAre you mystified by math word problems? This easy-to-understand guide shows you how to conquer these tricky questions with a step-by-step plan for finding the right solution each and every time, no matter the kind or level of problem. From learning math lingo and performing operations to calculating formulas and writing equations, you''ll get all the skills you need to succeed!Discover how to: * Translate word problems into plain English* Brush up on basic math skills* Plug in the right operation or formula* Tackle algebraic and geometric problems* Check your answers to see if they work

  10. "Real life" longevity of implantable cardioverter-defibrillator devices.

    Science.gov (United States)

    Manolis, Antonis S; Maounis, Themistoklis; Koulouris, Spyridon; Vassilikos, Vassilios

    2017-09-01

    Manufacturers of implantable cardioverter-defibrillators (ICDs) promise a 5- to 9-year projected longevity; however, real-life data indicate otherwise. The aim of the present study was to assess ICD longevity among 685 consecutive patients over the last 20 years. Real-life longevity of ICDs may differ from that stated by the manufacturers. The study included 601 men and 84 women (mean age, 63.1 ± 13.3 years). The underlying disease was coronary (n = 396) or valvular (n = 15) disease, cardiomyopathy (n = 220), or electrical disease (n = 54). The mean ejection fraction was 35%. Devices were implanted for secondary (n = 562) or primary (n = 123) prevention. Single- (n = 292) or dual-chamber (n = 269) or cardiac resynchronization therapy (CRT) devices (n = 124) were implanted in the abdomen (n = 17) or chest (n = 668). Over 20 years, ICD pulse generator replacements were performed in 238 patients (209 men; age 63.7 ± 13.9 years; ejection fraction, 37.7% ± 14.0%) who had an ICD for secondary (n = 210) or primary (n = 28) prevention. The mean ICD longevity was 58.3 ± 18.7 months. In 20 (8.4%) patients, devices exhibited premature battery depletion within 36 months. Most (94%) patients had none, minor, or modest use of ICD therapy. Longevity was longest for single-chamber devices and shortest for CRT devices. Latest-generation devices replaced over the second decade lasted longer compared with devices replaced during the first decade. When analyzed by manufacturer, Medtronic devices appeared to have longer longevity by 13 to 18 months. ICDs continue to have limited longevity of 4.9 ± 1.6 years, and 8% demonstrate premature battery depletion by 3 years. CRT devices have the shortest longevity (mean, 3.8 years) by 13 to 17 months, compared with other ICD devices. These findings have important implications, particularly in view of the high expense involved with this type of electrical

  11. Mixing problem based learning and conventional teaching methods in an analog electronics course

    NARCIS (Netherlands)

    Podges, J M; Kommers, P A M; Winnips, K; van Joolingen, W R

    2014-01-01

    This study, undertaken at the Walter Sisulu University of Technology (WSU) in South Africa, describes how problem-based learning (PBL) affects the first year 'analog electronics course', when PBL and the lecturing mode is compared. Problems were designed to match real-life situations. Data between

  12. Time-Frequency Feature Representation Using Multi-Resolution Texture Analysis and Acoustic Activity Detector for Real-Life Speech Emotion Recognition

    Directory of Open Access Journals (Sweden)

    Kun-Ching Wang

    2015-01-01

    Full Text Available The classification of emotional speech is mostly considered in speech-related research on human-computer interaction (HCI. In this paper, the purpose is to present a novel feature extraction based on multi-resolutions texture image information (MRTII. The MRTII feature set is derived from multi-resolution texture analysis for characterization and classification of different emotions in a speech signal. The motivation is that we have to consider emotions have different intensity values in different frequency bands. In terms of human visual perceptual, the texture property on multi-resolution of emotional speech spectrogram should be a good feature set for emotion classification in speech. Furthermore, the multi-resolution analysis on texture can give a clearer discrimination between each emotion than uniform-resolution analysis on texture. In order to provide high accuracy of emotional discrimination especially in real-life, an acoustic activity detection (AAD algorithm must be applied into the MRTII-based feature extraction. Considering the presence of many blended emotions in real life, in this paper make use of two corpora of naturally-occurring dialogs recorded in real-life call centers. Compared with the traditional Mel-scale Frequency Cepstral Coefficients (MFCC and the state-of-the-art features, the MRTII features also can improve the correct classification rates of proposed systems among different language databases. Experimental results show that the proposed MRTII-based feature information inspired by human visual perception of the spectrogram image can provide significant classification for real-life emotional recognition in speech.

  13. Generalized production planning problem under interval uncertainty

    Directory of Open Access Journals (Sweden)

    Samir A. Abass

    2010-06-01

    Full Text Available Data in many real life engineering and economical problems suffer from inexactness. Herein we assume that we are given some intervals in which the data can simultaneously and independently perturb. We consider the generalized production planning problem with interval data. The interval data are in both of the objective function and constraints. The existing results concerning the qualitative and quantitative analysis of basic notions in parametric production planning problem. These notions are the set of feasible parameters, the solvability set and the stability set of the first kind.

  14. Effects of Healthy Aging and Mild Cognitive Impairment on a Real-Life Decision-Making Task.

    Science.gov (United States)

    Pertl, Marie-Theres; Benke, Thomas; Zamarian, Laura; Delazer, Margarete

    2017-01-01

    In this study, we investigated the effects of age and of mild cognitive impairment (MCI) on decision making under risk by adopting a task representing real-life health-related situations and involving complex numerical information. Moreover, we assessed the relationship of real-life decision making to other cognitive functions such as number processing, executive functions, language, memory, and attention. For this reason, we compared the performance of 19 healthy, relatively younger adults with that of 18 healthy older adults and the performance of the 18 healthy older adults with that of 17 patients with MCI. Results indicated difficulties in real-life decision making for the healthy older adults compared with the healthy, relatively younger adults. Difficulties of patients with MCI relative to the healthy older adults arose in particular in difficult items requiring processing of frequencies and fractions. Significant effects of age and of MCI in processing frequencies were also evident in a ratio number comparison task. Decision-making performance of healthy participants and of the patient group correlated significantly with number processing. There was a further significant correlation with executive functions for the healthy participants and with reading comprehension for the patients. Our results suggest that healthy older individuals and patients with MCI make less advantageous decisions when the information is complex and high demands are put on executive functions and numerical abilities. Moreover, we show that executive functions and numerical abilities are not only essential in laboratory gambling tasks but also in more realistic and ecological decision situations within the health context.

  15. Relationship Between Sleep Problems and Quality of Life in Children With ADHD.

    Science.gov (United States)

    Yürümez, Esra; Kılıç, Birim Günay

    2016-01-01

    The purpose of this study is to assess the sleep behaviors, sleep problems and frequency, and relationship with psychiatric comorbidities in ADHD Combined type and to evaluate the effect of sleep problems on quality of life. Forty-six boys, aged 7 to 13 years, with ADHD-combined type and 31 healthy boys were included. ADHD children were never treated for sleep or psychiatric disorders. Intelligence quotient (IQ) test scores were minimum 80, body mass index were normal and did not have medical disorders. Parents completed Children's Sleep Habits Questionnaire, Conners' Parent Rating Scale and The Pediatric Quality of Life Inventory (PedsQL) and participants were asked about sleep behaviors and were administered PedsQL and Schedule for Affective Disorders and Schizophrenia. The frequency of sleep problems in ADHD is 84.8%, higher than the control group (p = .002). Evaluating PedsQL scores, the quality of life is worse in physical, psychosocial health, and total life quality (p children with ADHD compared with healthy control participants. As the ADHD group have more night wakings than the control group through the night, it is thought that night wakings that cause a partitioned sleep may be important signs seen in ADHD. That could be suggested by two hypotheses. First one is that, daytime sleepiness is more common in ADHD and those children present excessive hyperactivity during the day to stay awake and the second one is the improvement of ADHD signs when the drugs for sleepiness are used. Usage of standardized and valid diagnostic criteria, exclusion of adolescence, gender, socioeconomic level, primary sleep problems, medical disorders and low IQ level, making allowances for effect of comorbidities and having compared with the control group are the important methodological features of this study. The most important limitation of this study is small sample size that makes the findings less generalizable to other groups of children with ADHD, and another one is not

  16. Adapting the SLIM diabetes prevention intervention to a Dutch real-life setting: joint decision making by science and practice.

    Science.gov (United States)

    Jansen, Sophia C; Haveman-Nies, Annemien; Duijzer, Geerke; Ter Beek, Josien; Hiddink, Gerrit J; Feskens, Edith J M

    2013-05-08

    Although many evidence-based diabetes prevention interventions exist, they are not easily applicable in real-life settings. Moreover, there is a lack of examples which describe the adaptation process of these interventions to practice. In this paper we present an example of such an adaptation. We adapted the SLIM (Study on Lifestyle intervention and Impaired glucose tolerance Maastricht) diabetes prevention intervention to a Dutch real-life setting, in a joint decision making process of intervention developers and local health care professionals. We used 3 adaptation steps in accordance with current adaptation frameworks. In the first step, the elements of the SLIM intervention were identified. In the second step, these elements were judged for their applicability in a real-life setting. In the third step, adaptations were proposed and discussed for those elements which were deemed not applicable. Participants invited for this process included intervention developers and local health care professionals (n=19). In the first adaptation step, a total of 22 intervention elements were identified. In the second step, 12 of these 22 intervention elements were judged as inapplicable. In the third step, a consensus was achieved for the adaptations of all 12 elements. The adapted elements were in the following categories: target population, techniques, intensity, delivery mode, materials, organisational structure, and political and financial conditions. The adaptations either lay in changing the SLIM protocol (6 elements) or the real-life working procedures (1 element), or a combination of both (4 elements). The positive result of this study is that a consensus was achieved within a relatively short time period (nine months) between the developers of the SLIM intervention and local health care professionals on the adaptations needed to make SLIM applicable in a Dutch real-life setting. Our example shows that it is possible to combine the perspectives of scientists and

  17. Impact of omalizumab in children from a middle-income country with severe therapy-resistant asthma: A real-life study.

    Science.gov (United States)

    Pitrez, Paulo M; de Souza, Rodrigo G; Roncada, Cristian; Heinzmann-Filho, Joao P; Santos, Giovana; Pinto, Leonardo A; Jones, Marcus H; Stein, Renato T

    2017-11-01

    Severe asthma in children is a global health problem. Severe therapy-resistant asthma (STRA) in children is a major clinical challenge due to persistent symptoms despite high doses of corticosteroids and results in high public health costs. Omalizumab (anti-IgE monoclonal antibody) has been described as an effective add-on therapy in these patients. The characteristics of children with STRA from low- and middle-income countries have scarcely been reported, and no real-life study has been published on the effects of omalizumab in this group of patients. The aim of our study is to report the first clinical real-life experiences with omalizumab in Brazilian children with STRA. Children (6-18 years old) from a referral center who were diagnosed with STRA were included in this retrospective study based on our clinical databases. The included children had undergone at least 6 months of omalizumab treatment and fulfilled the following initial criteria: 1) >6 years old; 2) a positive skin-prick test for at least one aeroallergen; and 3) a serum total IgE level between 30 and 1500 IU/mL. Clinical and lung function variables were analyzed before and after treatment. Fourteen children (mean age: 11.9 years; percentage female: 72%) were included in this study. Omalizumab treatment significantly increased control of the disease according to a standardized questionnaire administered at every visit (P omalizumab in Brazilian children with STRA significantly improved disease control, decreased hospitalizations, and allowed suspension of continuous oral corticosteroids. © 2017 Wiley Periodicals, Inc.

  18. Exposure to stressful life events during pregnancy predicts psychotic experiences via behaviour problems in childhood.

    Science.gov (United States)

    Betts, Kim S; Williams, Gail M; Najman, Jakob M; Scott, James; Alati, Rosa

    2014-12-01

    Exposure to stressful life events during pregnancy has been associated with later schizophrenia in offspring. We explore how prenatal stress and neurodevelopmental abnormalities in childhood associate to increase the risk of later psychotic experiences. Participants from the Mater University Study of Pregnancy (MUSP), an Australian based, pre-birth cohort study were examined for lifetime DSM-IV positive psychotic experiences at 21 years by a semi-structured interview (n = 2227). Structural equation modelling suggested psychotic experiences were best represented with a bifactor model including a general psychosis factor and two group factors. We tested for an association between prenatal stressful life events with the psychotic experiences, and examined for potential moderation and mediation by behaviour problems and cognitive ability in childhood. Prenatal stressful life events predicted psychotic experiences indirectly via behaviour problems at child age five years, and this relationship was not confounded by maternal stressful life events at child age five. We found no statistical evidence for an interaction between prenatal stressful life events and behaviour problems or cognitive ability. The measurable effect of prenatal stressful life events on later psychotic experiences in offspring manifested as behaviour problems by age 5. By identifying early abnormal behavioural development as an intermediary, this finding further confirms the role of prenatal stress to later psychotic disorders. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Mixing Problem Based Learning And Conventional Teaching Methods In An Analog Electronics Course

    NARCIS (Netherlands)

    Podges, J.M.; Kommers, Petrus A.M.; Winnips, K.; van Joolingen, Wouter

    2014-01-01

    This study, undertaken at the Walter Sisulu University of Technology (WSU) in South Africa, describes how problem-based learning (PBL) affects the first year ‘analog electronics course’, when PBL and the lecturing mode is compared. Problems were designed to match real-life situations. Data between

  20. Center for Real Life Kitchen Design open house to showcase latest in residential kitchens

    OpenAIRE

    Elliott, Jean

    2007-01-01

    Virginia Tech will unveil its newly refurbished Center for Real Life Kitchen Design at an open house set for Monday, April 2. The 1,500-square foot center, located in 247 Wallace Hall, features six fully functional residential kitchen designs that reflect a variety of price levels, lifestyles, and use of space for today's homeowner.

  1. Working as simulated patient has effects on real patient life – Preliminary insights from a qualitative study

    Directory of Open Access Journals (Sweden)

    Simmenroth-Nayda, Anne

    2016-05-01

    Full Text Available Background: Persons who simulate patients during medical education understand the routines and the underlying script of medical consultations better. We aimed to explore how simulated patients (SPs integrated this new understanding into their daily life, how this work affected their private life as patients, and what we can learn from these changes for concepts of empowerment.Design, setting, and participants: A qualitative interview study. All SPs of Göttingen medical school who had been working longer than three semesters (n=14 were invited and agreed to take part in an open interview about their daily experience with real doctors. Documentary method was used to identify the main issues. Several cases were chosen according to maximum contrast and analysed by in-depth analysis to provide vivid examples of how simulations may affect the real life of the SPs as patients.Results: Our analysis revealed three main changes in the behaviour of SPs as real patients. They were more attentive, had a better understanding of the circumstances under which doctors work, and acted more self-confidently. From the selected cases it became apparent that working as a SP may lead to a constant and significant decrease of fear of hospitals and medical procedures or, in other cases, may enable the SPs to develop new abilities for giving feedback, questioning procedures, and explanations for real doctors.Conclusion: working as a simulated patient seems to be well-suited to understand own progression of diseases, to increase self-responsibility and to a confident attitude as patient.

  2. Does Playing Sports Video Games Predict Increased Involvement in Real-Life Sports Over Several Years Among Older Adolescents and Emerging Adults?

    Science.gov (United States)

    Adachi, Paul J C; Willoughby, Teena

    2016-02-01

    Given the extreme popularity of video games among older adolescents and emerging adults, the investigation of positive outcomes of video game play during these developmental periods is crucial. An important direction for research in this area is the investigation of a link between sports video game play and involvement in real-life sports among youth. Yet, this association has not been examined in the long-term among older adolescents and emerging adults, and thus represents an exciting new area for discovery. The primary goal of the current study, therefore, was to examine the long-term association between sports video game play and involvement in real-life sports clubs among older adolescents and emerging adults. In addition, we examined whether self-esteem was an underlying mechanism of this longitudinal association. We surveyed older adolescents and emerging adults (N = 1132; 70.6 % female; M age = 19.06 years, range of 17-25 years at the first assessment) annually over 3 years about their video game play, self-esteem, and involvement in real-life sports. We found a long-term predictive effect of sports video game play on increased involvement in real-life sports over the 3 years. Furthermore, we demonstrated that self-esteem was an underlying mechanism of this long-term association. Our findings make an important contribution to an emerging body of literature on the positive outcomes of video game play, as they suggest that sports video game play may be an effective tool to promote real-life sports participation and physical activity among older adolescents and emerging adults.

  3. The Other Side of the Screen - Simultaneously maintaining social relationships in real life and on social media

    OpenAIRE

    Gruenke, Solveig Wiland

    2017-01-01

    Social media as a social concept is becoming a prominent fixture in social life and is taking on a significant increase in social relevance, both academically and in popular discourse. The academic research is often focused on either the online content itself or the macro societal implications, more than the real-life social aspect of social media. People using social media are now simultaneously producing content about their life online, whilst they are, in fact, living it. The new social fe...

  4. The Time-Dependent Multiple-Vehicle Prize-Collecting Arc Routing Problem

    DEFF Research Database (Denmark)

    Black, Daniel; Eglese, Richard; Wøhlk, Sanne

    2015-01-01

    -life traffic situations where the travel times change with the time of day are taken into account. Two metaheuristic algorithms, one based on Variable Neighborhood Search and one based on Tabu Search, are proposed and tested for a set of benchmark problems, generated from real road networks and travel time......In this paper, we introduce a multi vehicle version of the Time-Dependent Prize-Collecting Arc Routing Problem (TD-MPARP). It is inspired by a situation where a transport manager has to choose between a number of full truck load pick-ups and deliveries to be performed by a fleet of vehicles. Real...

  5. Mapping real-life applications on run-time reconfigurable NoC-based MPSoC on FPGA.

    NARCIS (Netherlands)

    Singh, A.K.; Kumar, A.; Srikanthan, Th.; Ha, Y.

    2010-01-01

    Multiprocessor systems-on-chip (MPSoC) are required to fulfill the performance demand of modern real-life embedded applications. These MPSoCs are employing Network-on-Chip (NoC) for reasons of efficiency and scalability. Additionally, these systems need to support run-time reconfiguration of their

  6. Real-Life Challenges in Using Augmentative and Alternative Communication by Persons with Amyotrophic Lateral Sclerosis

    Science.gov (United States)

    Ray, Jayanti

    2015-01-01

    Given the linguistic and cognitive demands of communication, adult Augmentative and Alternative Communication (AAC) users with acquired communication disorders may have difficulty using AAC systems consistently and effectively in "real-life" situations. The process of recommending AAC systems and strategies is an area of exploration,…

  7. A review of simheuristics: Extending metaheuristics to deal with stochastic combinatorial optimization problems

    Directory of Open Access Journals (Sweden)

    Angel A. Juan

    2015-12-01

    Full Text Available Many combinatorial optimization problems (COPs encountered in real-world logistics, transportation, production, healthcare, financial, telecommunication, and computing applications are NP-hard in nature. These real-life COPs are frequently characterized by their large-scale sizes and the need for obtaining high-quality solutions in short computing times, thus requiring the use of metaheuristic algorithms. Metaheuristics benefit from different random-search and parallelization paradigms, but they frequently assume that the problem inputs, the underlying objective function, and the set of optimization constraints are deterministic. However, uncertainty is all around us, which often makes deterministic models oversimplified versions of real-life systems. After completing an extensive review of related work, this paper describes a general methodology that allows for extending metaheuristics through simulation to solve stochastic COPs. ‘Simheuristics’ allow modelers for dealing with real-life uncertainty in a natural way by integrating simulation (in any of its variants into a metaheuristic-driven framework. These optimization-driven algorithms rely on the fact that efficient metaheuristics already exist for the deterministic version of the corresponding COP. Simheuristics also facilitate the introduction of risk and/or reliability analysis criteria during the assessment of alternative high-quality solutions to stochastic COPs. Several examples of applications in different fields illustrate the potential of the proposed methodology.

  8. Children with Imaginary Companions Focus on Mental Characteristics When Describing Their Real-life Friends

    Science.gov (United States)

    Davis, Paige E.; Meins, Elizabeth; Fernyhough, Charles

    2014-01-01

    Relations between having an imaginary companion (IC) and (i) descriptions of a real-life friend, (ii) theory of mind performance, and (iii) reported prosocial behaviour and behavioural difficulties were investigated in a sample of 5-year-olds (N?=?159). Children who had an IC were more likely than their peers without an IC to describe their best…

  9. Mathematical Abstraction in the Solving of Ill-Structured Problems by Elementary School Students in Korea

    Science.gov (United States)

    Hong, Jee Yun; Kim, Min Kyeong

    2016-01-01

    Ill-structured problems can be regarded as one of the measures that meet recent social needs emphasizing students' abilities to solve real-life problems. This study aimed to analyze the mathematical abstraction process in solving such problems, and to identify the mathematical abstraction level ([I] Recognition of mathematical structure through…

  10. Gender differences in the pathway from adverse life events to adolescent emotional and behavioural problems via negative cognitive errors.

    Science.gov (United States)

    Flouri, Eirini; Panourgia, Constantina

    2011-06-01

    The aim of this study was to test for gender differences in how negative cognitive errors (overgeneralizing, catastrophizing, selective abstraction, and personalizing) mediate the association between adverse life events and adolescents' emotional and behavioural problems (measured with the Strengths and Difficulties Questionnaire). The sample consisted of 202 boys and 227 girls (aged 11-15 years) from three state secondary schools in disadvantaged areas in one county in the South East of England. Control variables were age, ethnicity, special educational needs, exclusion history, family structure, family socio-economic disadvantage, and verbal cognitive ability. Adverse life events were measured with Tiet et al.'s (1998) Adverse Life Events Scale. For both genders, we assumed a pathway from adverse life events to emotional and behavioural problems via cognitive errors. We found no gender differences in life adversity, cognitive errors, total difficulties, peer problems, or hyperactivity. In both boys and girls, even after adjustment for controls, cognitive errors were related to total difficulties and emotional symptoms, and life adversity was related to total difficulties and conduct problems. The life adversity/conduct problems association was not explained by negative cognitive errors in either gender. However, we found gender differences in how adversity and cognitive errors produced hyperactivity and internalizing problems. In particular, life adversity was not related, after adjustment for controls, to hyperactivity in girls and to peer problems and emotional symptoms in boys. Cognitive errors fully mediated the effect of life adversity on hyperactivity in boys and on peer and emotional problems in girls.

  11. Real Life Active Gaming Practices of 7-11-Year-Old Children.

    Science.gov (United States)

    Allsop, Susan; Rumbold, Penny Louise Sheena; Debuse, Dorothée; Dodd-Reynolds, Caroline

    2013-12-01

    In the laboratory, active gaming has been shown to increase physical activity levels in children compared with seated media activities. The information is sparse, however, about children's real life active gaming practices, and the laboratory protocols used thus far might not be representative. The purpose of the present study was to establish the sociodemographic characteristics, real life active gaming practices, and reasons for gameplay, to later inform intervention studies. An "Active Gaming Questionnaire" was purposely developed and distributed to 44 7-11-year-old children and their parents. Forty questionnaires were completed and returned. Analysis found 95 percent of the children had access to active gaming consoles "at home." The favorite console was the Nintendo (Kyoto, Japan) Wii™, and the favorite game was Nintendo "Wii Sports." The majority of children frequently played active games against other people. The average reported gameplay time was 81 minutes on 1-2 days per week, usually on a Saturday. More than half of the children (52.5 percent) consumed foods and/or drinks during play, which was significantly associated (P=0.000) with an extended average gameplay time (increased by 25 minutes). The majority of participants (65 percent) considered active gaming to be an alternative form of exercise, and main reasons for active videogame play included for entertainment, health benefits, and the environment. In conclusion, children 9.3±1.4 years old typically play Nintendo "Wii Sports," once or twice per week for 81 minutes. Reported active gameplay time is extended by 25 minutes when food and/or drinks are consumed.

  12. A Cellular Automata-Based Simulation Tool for Real Fire Accident Prevention

    Directory of Open Access Journals (Sweden)

    Jacek M. Czerniak

    2018-01-01

    Full Text Available Many serious real-life problems could be simulated using cellular automata theory. There were a lot of fires in public places which kill many people. Proposed method, called Cellular Automata Evaluation (CAEva in short, is using cellular automata theory and could be used for checking buildings conditions for fire accident. The tests performed on real accident showed that an appropriately configured program allows obtaining a realistic simulation of human evacuation. The authors analyze some real accidents and proved that CAEva method appears as a very promising solution, especially in the cases of building renovations or temporary unavailability of escape routes.

  13. Commentary: getting real on addressing health care disparities and other systems problems.

    Science.gov (United States)

    Madara, James L

    2012-06-01

    Physician membership organizations vary in the extent of their engagement in activities to address health disparities. Increasing engagement of those organizations not already highly active in this critical area is, thus, an opportunity. Studies that provide definitional contours of key issues, like disparities, are necessary and must be iteratively refined. However, parallel activities of intervention with measured outcomes to assess the effects of these interventions are necessary to truly address major problems in the health care system. To date, work in the problem definition category exceeds work toward intervention in and mitigation of these problems with measured outcomes. Many problems in health care, including disparities, are now sufficiently understood that it is time to shift focus toward bold intervention with measured outcomes. Optimal approaches that yield superior outcomes generally require collaboration across the provider-payer spectrum and the private sectors, including physicians, hospitals, insurers, etc. Stakeholders are now free to act in such coordinated fashion; it only requires social capital that permits cooperation and compromise. Interventions for problems such as health care disparities can be developed in the private sector and mirrored by government payers if physicians and organizations can get real about collaborating to implement outcomes-based initiatives to improve the health of all patients.

  14. The art and science of problem solving

    DEFF Research Database (Denmark)

    Vidal, Rene Victor Valqui

    2005-01-01

    In this paper we will document that real-life problem solving in complex situations demands both rational (scientific) and intuitive (artistic) thinking. First, the concepts of art and science will be discussed; differences and similarities will be enhanced. Thereafter the concept of group problem...... solving facilitation both as science and art will be presented. A case study related to examination's planning will be discussed to illustrate the main concepts in practice. In addition, other cases studies will also be shortly presented....

  15. Quality of life of people with mental health problems: a synthesis of qualitative research

    OpenAIRE

    Connell, Janice; Brazier, John; O?Cathain, Alicia; Lloyd-Jones, Myfanwy; Paisley, Suzy

    2012-01-01

    Abstract Purpose To identify the domains of quality of life important to people with mental health problems. Method A systematic review of qualitative research undertaken with people with mental health problems using a framework synthesis. Results We identified six domains: well-being and ill-being; control, autonomy and choice; self-perception; belonging; activity; and hope and hopelessness. Firstly, symptoms or ‘ill-being’ were an intrinsic aspect of quality of life for people with severe m...

  16. Registration accuracy and quality of real-life images.

    Directory of Open Access Journals (Sweden)

    Wei-Yen Hsu

    Full Text Available BACKGROUND: A common registration problem for the application of consumer device is to align all the acquired image sequences into a complete scene. Image alignment requires a registration algorithm that will compensate as much as possible for geometric variability among images. However, images captured views from a real scene usually produce different distortions. Some are derived from the optic characteristics of image sensors, and others are caused by the specific scenes and objects. METHODOLOGY/PRINCIPAL FINDINGS: An image registration algorithm considering the perspective projection is proposed for the application of consumer devices in this study. It exploits a multiresolution wavelet-based method to extract significant features. An analytic differential approach is then proposed to achieve fast convergence of point matching. Finally, the registration accuracy is further refined to obtain subpixel precision by a feature-based modified Levenberg-Marquardt method. Due to its feature-based and nonlinear characteristic, it converges considerably faster than most other methods. In addition, vignette compensation and color difference adjustment are also performed to further improve the quality of registration results. CONCLUSIONS/SIGNIFICANCE: The performance of the proposed method is evaluated by testing the synthetic and real images acquired by a hand-held digital still camera and in comparison with two registration techniques in terms of the squared sum of intensity differences (SSD and correlation coefficient (CC. The results indicate that the proposed method is promising in registration accuracy and quality, which are statistically significantly better than other two approaches.

  17. Various forms of indexing HDMR for modelling multivariate classification problems

    Energy Technology Data Exchange (ETDEWEB)

    Aksu, Çağrı [Bahçeşehir University, Information Technologies Master Program, Beşiktaş, 34349 İstanbul (Turkey); Tunga, M. Alper [Bahçeşehir University, Software Engineering Department, Beşiktaş, 34349 İstanbul (Turkey)

    2014-12-10

    The Indexing HDMR method was recently developed for modelling multivariate interpolation problems. The method uses the Plain HDMR philosophy in partitioning the given multivariate data set into less variate data sets and then constructing an analytical structure through these partitioned data sets to represent the given multidimensional problem. Indexing HDMR makes HDMR be applicable to classification problems having real world data. Mostly, we do not know all possible class values in the domain of the given problem, that is, we have a non-orthogonal data structure. However, Plain HDMR needs an orthogonal data structure in the given problem to be modelled. In this sense, the main idea of this work is to offer various forms of Indexing HDMR to successfully model these real life classification problems. To test these different forms, several well-known multivariate classification problems given in UCI Machine Learning Repository were used and it was observed that the accuracy results lie between 80% and 95% which are very satisfactory.

  18. Development of a diagnostic decision tree for obstructive pulmonary diseases based on real-life data

    NARCIS (Netherlands)

    Metting, Esther I; In 't Veen, Johannes C C M; Dekhuijzen, P N Richard; van Heijst, Ellen; Kocks, Janwillem W H; Muilwijk-Kroes, Jacqueline B; Chavannes, Niels H; van der Molen, Thys

    2016-01-01

    The aim of this study was to develop and explore the diagnostic accuracy of a decision tree derived from a large real-life primary care population. Data from 9297 primary care patients (45% male, mean age 53±17 years) with suspicion of an obstructive pulmonary disease was derived from an

  19. Real-geographic-scenario-based virtual social environments: integrating geography with social research

    OpenAIRE

    Min Chen; Li He; Hui Lin; Chunxiao Zhang; Mingyuan Hu

    2013-01-01

    Existing online virtual worlds, or electronic environments, are of great significance to social science research, but are somewhat lacking in rigour. One reason is that users might not participate in those virtual worlds in the way they act in real daily life, communicating with each other in familiar environments and interacting with natural phenomena under the constraints of the human–land relationship. To help solve this problem we propose the real-geographic-scenario-based virtual social ...

  20. [Required Framework for the Collection of Real-life Data: An Example from University Eye Hospital Munich].

    Science.gov (United States)

    Kortüm, Karsten; Kern, Christoph; Meyer, Gerhard; Priglinger, Siegfried; Hirneiß, Christoph

    2017-12-01

    Background The importance of evaluating real-life data is constantly increasing. Currently available computer systems better allow for analyses of data, as more and more data is available in a digital form. Before a project for real-life data analyses is started, technical considerations and staff, legal, and data protection procedures need to be addressed. In this manuscript, experiences made at the University Eye Hospital in Munich will be shared. Materials and Methods Legal requirements, as found in laws and guidelines governing documentation and data privacy, are highlighted. Technical requirements for information technology infrastructure and software are defined. A survey conducted by the German Ophthalmological Society, among German eye hospitals investigating the current state of digitalization, was conducted. Also, staff requirements are outlined. Results A database comprising results of 330,801 patients was set up. It includes all diagnoses, procedures, clinical findings and results from diagnostic devices. This database was approved by the local data protection officer. In less than half of German eye hospitals (n = 21) that participated in the survey (n = 54), a complete electronic documentation is done. Fourteen institutions are completely paper-based, and the remainder of the hospitals used a mixed system. Conclusion In this work, we examined the framework that is required to develop a comprehensive database containing real-life data from clinics. In future, these databases will become increasingly important as more and more innovation are made in decision support systems. The base for this is comprehensive and well-curated databases. Georg Thieme Verlag KG Stuttgart · New York.

  1. Nonlinear Heart Rate Variability features for real-life stress detection. Case study: students under stress due to university examination.

    Science.gov (United States)

    Melillo, Paolo; Bracale, Marcello; Pecchia, Leandro

    2011-11-07

    This study investigates the variations of Heart Rate Variability (HRV) due to a real-life stressor and proposes a classifier based on nonlinear features of HRV for automatic stress detection. 42 students volunteered to participate to the study about HRV and stress. For each student, two recordings were performed: one during an on-going university examination, assumed as a real-life stressor, and one after holidays. Nonlinear analysis of HRV was performed by using Poincaré Plot, Approximate Entropy, Correlation dimension, Detrended Fluctuation Analysis, Recurrence Plot. For statistical comparison, we adopted the Wilcoxon Signed Rank test and for development of a classifier we adopted the Linear Discriminant Analysis (LDA). Almost all HRV features measuring heart rate complexity were significantly decreased in the stress session. LDA generated a simple classifier based on the two Poincaré Plot parameters and Approximate Entropy, which enables stress detection with a total classification accuracy, a sensitivity and a specificity rate of 90%, 86%, and 95% respectively. The results of the current study suggest that nonlinear HRV analysis using short term ECG recording could be effective in automatically detecting real-life stress condition, such as a university examination.

  2. Optimal portfolio selection for general provisioning and terminal wealth problems

    NARCIS (Netherlands)

    van Weert, K.; Dhaene, J.; Goovaerts, M.

    2010-01-01

    In Dhaene et al. (2005), multiperiod portfolio selection problems are discussed, using an analytical approach to find optimal constant mix investment strategies in a provisioning or a savings context. In this paper we extend some of these results, investigating some specific, real-life situations.

  3. Optimal portfolio selection for general provisioning and terminal wealth problems

    NARCIS (Netherlands)

    van Weert, K.; Dhaene, J.; Goovaerts, M.

    2009-01-01

    In Dhaene et al. (2005), multiperiod portfolio selection problems are discussed, using an analytical approach to find optimal constant mix investment strategies in a provisioning or savings context. In this paper we extend some of these results, investigating some specific, real-life situations. The

  4. Trial efficacy vs real world effectiveness in first line treatment of multiple myeloma

    NARCIS (Netherlands)

    Liwing, J.; Heeg, B.M.; Karstorp, S.; Postma, M.; Silvennoinen, R.; Putkonen, M.; Anttila, P.; Remes, K.; Abildgaard, N.; Waage, A.; Nahi, H.

    2015-01-01

    Background: Large randomized clinical trials (RCT) are the foundation of the registration of newly developed drugs. A potential problem with RCTs is that the inclusion/exclusion criteria will make the population different from the actual population treated in real life. Hence, it is important to

  5. What is the problem? A taxonomy of life problems and their relation to subjective well-being in middle and late adulthood

    NARCIS (Netherlands)

    Westerhof, G.J.; Thissen, A.J.C.; Dittmann-Kohli, F.; Stevens, N.L.

    2006-01-01

    Research on subjective well-being has focused mainly on positive values and goals. This article studies the structure and content of life problems from a theory of personal meaning as well as the relation of these problems to subjective well-being. Data from the German Aging Survey, a representative

  6. Critical Care Nurses Inadequately Assess SAPS II Scores of Very Ill Patients in Real Life

    Directory of Open Access Journals (Sweden)

    Andreas Perren

    2012-01-01

    Full Text Available Background. Reliable ICU severity scores have been achieved by various healthcare workers but nothing is known regarding the accuracy in real life of severity scores registered by untrained nurses. Methods. In this retrospective multicentre audit, three reviewers independently reassessed 120 SAPS II scores. Correlation and agreement of the sum-scores/variables among reviewers and between nurses and the reviewers’ gold standard were assessed globally and for tertiles. Bland and Altman (gold standard—nurses of sum scores and regression of the difference were determined. A logistic regression model identifying risk factors for erroneous assessments was calculated. Results. Correlation for sum scores among reviewers was almost perfect (mean ICC = 0.985. The mean (±SD nurse-registered SAPS II sum score was 40.3±20.2 versus 44.2±24.9 of the gold standard (32 points scores. The lowest agreement was found in high SAPS II tertiles for haemodynamics (k = 0.45–0.51. Conclusions. In real life, nurse-registered SAPS II scores of very ill patients are inaccurate. Accuracy of scores was not associated with nurses’ characteristics.

  7. Work Dissatisfaction and Sleep Problems among Canadians in the Latter Half of Life.

    Science.gov (United States)

    Brown, Kyla; Bierman, Alex

    2017-09-01

    This study examined the relationship between work dissatisfaction and sleep problems among Canadian adults in the latter half of life, as well as how gender and social contact moderate this relationship. Data were obtained from the Canadian General Social Survey, Cycle 21 (2007), which sampled adults aged 45 and older in 2007. Analyses focused on individuals with employment as their main activity. Analyses show that work dissatisfaction positively predicts trouble sleeping. There are no significant gender differences in this relationship. Social contact with friends buffers this relationship, but social contact with family does not, and buffering does not vary significantly between men and women. This research contributes to knowledge on sleep problems by showing that work dissatisfaction is adversely associated with sleep problems among Canadians in the latter half of life, but social contact with friends can weaken this deleterious relationship.

  8. Drop-out rate among patients treated with omalizumab for severe asthma: Literature review and real-life experience.

    Science.gov (United States)

    Caminati, M; Senna, G; Stefanizzi, G; Bellamoli, R; Longhi, S; Chieco-Bianchi, F; Guarnieri, G; Tognella, S; Olivieri, M; Micheletto, C; Festi, G; Bertocco, E; Mazza, M; Rossi, A; Vianello, A

    2016-08-25

    In patients with asthma, particularly severe asthma, poor adherence to inhaled drugs negatively affects the achievement of disease control. A better adherence rate is expected in the case of injected drugs, such as omalizumab, as they are administered only in a hospital setting. However, adherence to omalizumab has never been systematically investigated. The aim of this study was to review the omalizumab drop-out rate in randomized controlled trials (RCTs) and real-life studies. A comparative analysis was performed between published data and the Italian North East Omalizumab Network (NEONet) database. In RCTs the drop-out rate ranged from 7.1 to 19.4 %. Although the reasons for withdrawal were only occasionally reported, patient decision and adverse events were the most frequently reported causes. In real-life studies the drop-out rate ranged from 0 to 45.5 %. In most cases lack of efficacy was responsible for treatment discontinuation. According to NEONet data, 32 % of treated patients dropped out, with an increasing number of drop outs observed over time. Patient decision and lack of efficacy accounted for most treatment withdrawals. Treatment adherence is particularly crucial in patients with severe asthma considering the clinical impact of the disease and the cost of non-adherence. The risk of treatment discontinuation has to be carefully considered both in the experimental and real-life settings. Increased knowledge regarding the main reasons for patient withdrawal is important to improve adherence in clinical practice.

  9. Real-Life Treatment Paradigms Show Adalimumab Is Cost-Effective for the Management of Ulcerative Colitis

    Directory of Open Access Journals (Sweden)

    Candace L. Beilman

    2016-01-01

    Full Text Available Background. Adalimumab is effective for the maintenance of remission in patients with moderate-to-severe ulcerative colitis (UC. Currently, biologic therapies are used in cases where patients fail conventional medical therapies. If biologic therapies are not available, patients often choose to remain in an unwell state rather than undergo colectomy. Objective. The aim of the study was to evaluate the cost-effectiveness of adalimumab in patients with UC where adalimumab was readily available compared to not available. Methods. A previously validated Markov model was used to simulate disease progression of patients with UC who are corticosteroid-dependent and/or did not respond to thiopurine therapy. Utility scores and transition probabilities between health states were determined by using data from randomized controlled trials and real-life observational studies. Costs were obtained from the Ontario Case Costing Initiative and the Alberta Health Schedule of Medical Benefits. Results. The incremental cost-effectiveness ratios for readily available adalimumab treatment of UC were $40,000 and $59,000 per quality-adjusted life year, compared with ongoing medical therapy in an unwell state, at 5-year and 10-year treatment time horizons, respectively. Conclusion. Considering real-life patient preferences to avoid colectomy, adalimumab is cost-effective according to a willingness-to-pay threshold of $80,000 for treatment of UC.

  10. The role of general cognitive ability in moderating the relation of adverse life events to emotional and behavioural problems.

    Science.gov (United States)

    Flouri, Eirini; Mavroveli, Stella; Panourgia, Constantina

    2013-02-01

    Previous studies have established the role of various measures of cognitive functioning in dampening the association between adverse life events ('life stress') and adolescents' emotional and behavioural problems. However, it is not yet clear if general cognitive ability ('intelligence') is a protective factor. In this study of 1,175 10- to 19-year-olds in five secondary schools in England, we explored this issue. We found that even after controlling for sex, age, family poverty, and special educational needs, the association of life stress with emotional, hyperactivity, and conduct problems was significant. General cognitive ability moderated the association between life stress and conduct problems; among adolescents with higher than average general cognitive ability, the association between life stress and conduct problems was non-significant. © 2012 The British Psychological Society.

  11. What do we know about real exchange rate non-linearities?

    DEFF Research Database (Denmark)

    Kruse, Robinson; Frömmel, Michael; Menkhoff, Lukas

    correctly and misspecified non-linear alternatives is analyzed by means of a Monte Carlo study. The chosen parametrization is obtained by real-life exchange rates. The test against ESTAR has low power against all alternatives whereas the proposed unit root test against a Markov Switching autoregressive......This research points to the serious problem of potentially misspecified alternative hypotheses when testing for unit roots in real exchange rates. We apply a popular unit root test against nonlinear ESTAR and develop a Markov Switching unit root test. The empirical power of these tests against...... model performs clearly better. An empirical application of these tests suggests that real exchange rates may indeed be explained by Markov-Switching dynamics....

  12. 3D Interactions between Virtual Worlds and Real Life in an E-Learning Community

    Directory of Open Access Journals (Sweden)

    Ulrike Lucke

    2011-01-01

    Full Text Available Virtual worlds became an appealing and fascinating component of today's internet. In particular, the number of educational providers that see a potential for E-Learning in such new platforms increases. Unfortunately, most of the environments and processes implemented up to now do not exceed a virtual modelling of real-world scenarios. In particular, this paper shows that Second Life can be more than just another learning platform. A flexible and bidirectional link between the reality and the virtual world enables synchronous and seamless interaction between users and devices across both worlds. The primary advantages of this interconnection are a spatial extension of face-to-face and online learning scenarios and a closer relationship between virtual learners and the real world.

  13. The correlation between pedestrian injury severity in real-life crashes and Euro NCAP pedestrian test results.

    Science.gov (United States)

    Strandroth, Johan; Rizzi, Matteo; Sternlund, Simon; Lie, Anders; Tingvall, Claes

    2011-12-01

    The aim of the present study was to estimate the correlation between Euro NCAP pedestrian rating scores and injury outcome in real-life car-to-pedestrian crashes, with special focus on long-term disability. Another aim was to determine whether brake assist (BA) systems affect the injury outcome in real-life car-to-pedestrian crashes and to estimate the combined effects in injury reduction of a high Euro NCAP ranking score and BA. In the current study, the Euro NCAP pedestrian scoring was compared with the real-life outcome in pedestrian crashes that occurred in Sweden during 2003 to 2010. The real-life crash data were obtained from the data acquisition system Swedish Traffic Accident Data Acquisition (STRADA), which combines police records and hospital admission data. The medical data consisted of International Classification of Diseases (ICD) diagnoses and Abbreviated Injury Scale (AIS) scoring. In all, approximately 500 pedestrians submitted to hospital were included in the study. Each car model was coded according to Euro NCAP pedestrian scores. In addition, the presence or absence of BA was coded for each car involved. Cars were grouped according to their scoring. Injury outcomes were analyzed with AIS and, at the victim level, with permanent medical impairment. This was done by translating the injury scores for each individual to the risk of serious consequences (RSC) at 1, 5, and 10 percent risk of disability level. This indicates the total risk of a medical disability for each victim, given the severity and location of injuries. The mean RSC (mRSC) was then calculated for each car group and t-tests were conducted to falsify the null hypothesis at p ≤ .05 that the mRSC within the groups was equal. The results showed a significant reduction of injury severity for cars with better pedestrian scoring, although cars with a high score could not be studied due to lack of cases. The reduction in RSC for medium-performing cars in comparison with low-performing cars

  14. The art and science of participative problem solving

    DEFF Research Database (Denmark)

    Vidal, Rene Victor Valqui

    In this paper we will document that real-life problem solving in complex situations demands both rational (scientific) and intuitive (artistic) thinking. First, the concepts of art and science will be discussed; differences and similarities will be enhanced. Thereafter the concept of group problem...... solving facilitation both as science and art will be presented. A case study related to examinations planning will be discussed to illustrate the main concepts in practice. In addition, other cases studies will also be shortly presented....

  15. Computational Chemistry Laboratory: Calculating the Energy Content of Food Applied to a Real-Life Problem

    Science.gov (United States)

    Barbiric, Dora; Tribe, Lorena; Soriano, Rosario

    2015-01-01

    In this laboratory, students calculated the nutritional value of common foods to assess the energy content needed to answer an everyday life application; for example, how many kilometers can an average person run with the energy provided by 100 g (3.5 oz) of beef? The optimized geometries and the formation enthalpies of the nutritional components…

  16. Desiderio e scrittura in "The Real Life of Sebastian Knight" di Vladimir Nabokov

    Directory of Open Access Journals (Sweden)

    Valeria Invernizzi

    2014-12-01

    This paper examines, from a psychoanalytic standpoint, the intersection between identity and writing in the novel The Real Life of Sebastian Knight (1941 by Vladimir Nabokov. In particular, in the wake of Freud and Lacan, the following contribution will take the notions of desire, signifier, and the process of sublimation involved in artistic creation as interpretative devices. The main focus of the analysis will be the relationship between the two half-brothers of the novel, V (the narrator and Sebastian. First, I will show that Sebastian Knight holds the role of the object of desire for the characters who have established a close relationship with him and, in particular, for V. Secondly, the paper will be devoted to the analysis of the trauma experienced by the characters because of Sebastian's death, with a particular focus on the narrator's mourning through writing (the fictional biography we read in the novel; in the end, I will give evidence of the so-called signifier’s fallacy, crucial episodes in which the narrator can experience an insight into the truth of desire. Because of the not negligible question of the fictional paternity of The Real Life and the equally essential matter of V’s ‘stylistic touch’, metaliterary aspects of the novel will also be part of the following reading of the text.

  17. Alcohol-related problems and life satisfaction predict motivation to change among mandated college students.

    Science.gov (United States)

    Diulio, Andrea R; Cero, Ian; Witte, Tracy K; Correia, Christopher J

    2014-04-01

    The present study investigated the role specific types of alcohol-related problems and life satisfaction play in predicting motivation to change alcohol use. Participants were 548 college students mandated to complete a brief intervention following an alcohol-related policy violation. Using hierarchical multiple regression, we tested for the presence of interaction and quadratic effects on baseline data collected prior to the intervention. A significant interaction indicated that the relationship between a respondent's personal consequences and his/her motivation to change differs depending upon the level of concurrent social consequences. Additionally quadratic effects for abuse/dependence symptoms and life satisfaction were found. The quadratic probes suggest that abuse/dependence symptoms and poor life satisfaction are both positively associated with motivation to change for a majority of the sample; however, the nature of these relationships changes for participants with more extreme scores. Results support the utility of using a multidimensional measure of alcohol related problems and assessing non-linear relationships when assessing predictors of motivation to change. The results also suggest that the best strategies for increasing motivation may vary depending on the types of alcohol-related problems and level of life satisfaction the student is experiencing and highlight potential directions for future research. Copyright © 2014. Published by Elsevier Ltd.

  18. Genetic influence on blood pressure measured in the office, under laboratory stress and during real life

    NARCIS (Netherlands)

    Wang, Xiaoling; Ding, Xiuhua; Su, Shaoyong; Harshfield, Gregory; Treiber, Frank; Snieder, Harold

    To determine to what extent the genetic influences on blood pressure (BP) measured in the office, under psychologically stressful conditions in the laboratory and during real life are different from each other. Office BP, BP during a video game challenge and a social stressor interview, and 24-h

  19. Profiles of Observed Infant Anger Predict Preschool Behavior Problems: Moderation by Life Stress

    Science.gov (United States)

    Brooker, Rebecca J.; Buss, Kristin A.; Lemery-Chalfant, Kathryn; Aksan, Nazan; Davidson, Richard J.; Goldsmith, H. Hill

    2014-01-01

    Using both traditional composites and novel profiles of anger, we examined associations between infant anger and preschool behavior problems in a large, longitudinal data set (N = 966). We also tested the role of life stress as a moderator of the link between early anger and the development of behavior problems. Although traditional measures of…

  20. EVALUATION OF LAND BASED ON MARKET PRICE OBJECTS OF REAL ESTATE IN UKRAINE: PROBLEMS AND WAYS OF THEIR SOLUTIONS

    Directory of Open Access Journals (Sweden)

    MARTYN А. G.

    2017-03-01

    Full Text Available Summary. Raising of problem. During the reform of land and property relations, has been carried out in Ukraine since the early 1990s, land plots and buildings received the status of goods, participate in economic turnover, have value and price. At the same time, not the most important prerequisite for the introduction in Ukraine of a mass valuation of real estate, which is intended to become a base for the fair taxation of land plots and other real estate, should be the systematic collection of mass data on the market prices of real estate. Constant changes, additions and improvements to the current normative monetary assessment of land do not give a real change in the methodology of assessment because it is based on regulatory indicators, there is a non-market based assessment. This approach does not give positive results and in the overwhelming majority we distort the evaluation indicators. As a result, there is a situation where in some places the price of a square meter is much lower than the market (real price, while in others it is much higher than the actual price. Thus, the transition to the use of monetary land valuation, which is based on mass market indicators (mass valuation, will get rid of the regulatory indicators by introducing a market valuation base. Purpose. Conduct an analysis of the current state of monetary valuation of land in Ukraine, form the main problems of the modern land assessment area and guide the ways to improve and transition to market valuation of land based on widespread use of mass data on market prices of real estate. Conclusion. The analysis of the current state of the monetary valuation of land shows a significant deviation of the evaluation results with real market prices, indicating the imperfection of the existing method of normative monetary evaluation. Mass evaluation in the short term can solve the problems with the reliability of the estimates and improve the system of land taxation.

  1. Constraint satisfaction problems CSP formalisms and techniques

    CERN Document Server

    Ghedira, Khaled

    2013-01-01

    A Constraint Satisfaction Problem (CSP) consists of a set of variables, a domain of values for each variable and a set of constraints. The objective is to assign a value for each variable such that all constraints are satisfied. CSPs continue to receive increased attention because of both their high complexity and their omnipresence in academic, industrial and even real-life problems. This is why they are the subject of intense research in both artificial intelligence and operations research. This book introduces the classic CSP and details several extensions/improvements of both formalisms a

  2. Framing Mass Shootings: Fictional Depictions of Real-life Gun Massacres in American Cinema

    OpenAIRE

    Tryggeseid, Ane Johannessen

    2017-01-01

    This thesis examines the concept of real-life mass shootings and its depiction in American fictional cinema. The issue of mass shootings is a highly controversial subject of discussion, both within the public and political sphere, as it necessarily touches upon rigid perceptions of civil liberties – specifically those of the Second Amendment – which further permeates the field of fictional cinema. As opposed to assessing the issue of mass shootings as a product of a prevailing culture of guns...

  3. A Genre-Specific Investigation of Video Game Engagement and Problem Play in the Early Life Course.

    Science.gov (United States)

    Ream, Geoffrey L; Elliott, Luther C; Dunlap, Eloise

    2013-05-21

    This study explored predictors of engagement with specific video game genres, and degree of problem play experienced by players of specific genres, during the early life course. Video game players ages 18-29 (n = 692) were recruited in and around video game retail outlets, arcades, conventions, and other video game related contexts in New York City. Participants completed a Computer-Assisted Personal Interview (CAPI) of contemporaneous demographic and personality measures and a Life-History Calendar (LHC) measuring video gaming, school/work engagement, and caffeine and sugar consumption for each year of life ages 6 - present. Findings were that likelihood of engagement with most genres rose during childhood, peaked at some point during the second decade of life, and declined through emerging adulthood. Cohorts effects on engagement also emerged which were probably attributable to changes in the availability and popularity of various genres over the 12-year age range of our participants. The relationship between age and problem play of most genres was either negative or non-significant. Sensation-seeking was the only consistent positive predictor of problem play. Relationships between other variables and engagement with and problem play of specific genres are discussed in detail.

  4. Validation of performance of real-time kinematic PPP. A possible tool for deformation monitoring

    OpenAIRE

    Martín Furones, Ángel Esteban; Anquela Julián, Ana Belén; DIMAS PAGÉS, ALEJANDRO; Cos-Gayón López, Fernando José

    2015-01-01

    Structural failures (bridge or building collapses) and geohazards (landslides, ground subsi- dence or earthquakes) are worldwide problems that often lead to significant economic and loss of life. Monitoring the deformation of both natural phenomena and man-made struc- tures is a major key to assessing structural dynamic responses. Actually, this monitoring process is under real-time demand for developing warning and alert systems. One of the most used techniques for real-time deformation m...

  5. A Delphi Study to Detect Deficiencies and Propose Actions in Real Life Treatment of Neovascular Age-Related Macular Degeneration

    Directory of Open Access Journals (Sweden)

    Alfredo García-Layana

    2014-01-01

    Full Text Available Purpose. Spanish retina specialists were surveyed in order to propose actions to decrease deficiencies in real-life neovascular age macular degeneration treatment (nv-AMD. Methods. One hundred experts, members of the Spanish Vitreoretinal Society (SERV, were invited to complete an online survey of 52 statements about nv-AMD management with a modified Delphi methodology. Four rounds were performed using a 5-point Linkert scale. Recommendations were developed after analyzing the differences between the results and the SERV guidelines recommendations. Results. Eighty-seven specialists completed all the Delphi rounds. Once major potential deficiencies in real-life nv-AMD treatment were identified, 15 recommendations were developed with a high level of agreement. Consensus statements to reduce the burden of the disease included the use of treat and extend regimen and to reduce the amount of diagnostic tests during the loading phase and training technical staff to perform these tests and reduce the time between relapse detection and reinjection, as well as establishing patient referral protocols to outside general ophthalmology clinics. Conclusion. The level of agreement with the final recommendations for nv-AMD treatment among Spanish retinal specialist was high indicating that some actions could be applied in order to reduce the deficiencies in real-life nv-AMD treatment.

  6. Discrete harmony search algorithm for scheduling and rescheduling the reprocessing problems in remanufacturing: a case study

    Science.gov (United States)

    Gao, Kaizhou; Wang, Ling; Luo, Jianping; Jiang, Hua; Sadollah, Ali; Pan, Quanke

    2018-06-01

    In this article, scheduling and rescheduling problems with increasing processing time and new job insertion are studied for reprocessing problems in the remanufacturing process. To handle the unpredictability of reprocessing time, an experience-based strategy is used. Rescheduling strategies are applied for considering the effect of increasing reprocessing time and the new subassembly insertion. To optimize the scheduling and rescheduling objective, a discrete harmony search (DHS) algorithm is proposed. To speed up the convergence rate, a local search method is designed. The DHS is applied to two real-life cases for minimizing the maximum completion time and the mean of earliness and tardiness (E/T). These two objectives are also considered together as a bi-objective problem. Computational optimization results and comparisons show that the proposed DHS is able to solve the scheduling and rescheduling problems effectively and productively. Using the proposed approach, satisfactory optimization results can be achieved for scheduling and rescheduling on a real-life shop floor.

  7. Menu-engineering in restaurants - adapting portion sizes on plates to enhance vegetable consumption: a real-life experiment.

    NARCIS (Netherlands)

    Reinders, M.J.; Huitink, M.; Dijkstra, S.C.; Maaskant, A.J.; Heijnen, J.

    2017-01-01

    Background: The aim of this research was to investigate whether increased portion sizes of vegetables and decreased portion sizes of meat on main dishes increased the amount of vegetables consumed in a real-life restaurant setting without affecting customer satisfaction. The participants were

  8. Management of bipolar disorder in the intercontinental region: an international, multicenter, non-interventional, cross-sectional study in real-life conditions.

    Science.gov (United States)

    Samalin, Ludovic; Vieta, Eduard; Okasha, Tarek Ahmed; Uddin, Mm Jalal; Ahmadi Abhari, Seyed Ali; Nacef, Fethi; Mishyiev, Vyacheslav; Aizenberg, Dovi; Ratner, Yaël; Melas-Melt, Lydie; Sedeki, Idir; Llorca, Pierre Michel

    2016-05-16

    Most of the existing data on real-life management of bipolar disorder are from studies conducted in western countries (mostly United States and Europe). This multinational, observational cohort study aimed to describe the management and clinical outcomes of bipolar patients in real-life conditions across various intercontinental countries (Bangladesh, Egypt, Iran, Israel, Tunisia, and Ukraine). Data on socio-demographic and disease characteristics, current symptomatology, and pharmacological treatment were collected. Comparisons between groups were performed using standard statistical tests. Overall, 1180 patients were included. The median time from initial diagnosis was 80 months. Major depressive disorder was the most common initial diagnosis. Mood stabilizers and antipsychotics were the most common drugs being prescribed at the time of the study. Antidepressants (mainly selective serotonin uptake inhibitors [SSRIs]) were administered to 36.1% of patients. Patients with bipolar I disorder received higher number of antipsychotics and anxiolytics than those with bipolar II disorder (p Bipolar disorder real-life management practice, irrespective of region, shows a delay in diagnosis and an overuse of antidepressants. Clinical decision-making appears to be based on a multidimensional approach related to current symptomatology and type of bipolar disorder.

  9. Enhancing Problem-Based Learning Designs with a Single E-Learning Scaffolding Tool: Two Case Studies Using Challenge FRAP

    Science.gov (United States)

    Stewart, Terry M.; MacIntyre, William R.; Galea, Victor J.; Steel, Caroline H.

    2007-01-01

    Problem-based learning (PBL) is a powerful instructional approach. By working through assessable complex problem-solving tasks learners can be encouraged to actively engage in investigation and inquiry and to use high level cognitive thought processes to solve real-life problems in professional contexts. A critical element of a successful PBL…

  10. Simplified neural networks for solving linear least squares and total least squares problems in real time.

    Science.gov (United States)

    Cichocki, A; Unbehauen, R

    1994-01-01

    In this paper a new class of simplified low-cost analog artificial neural networks with on chip adaptive learning algorithms are proposed for solving linear systems of algebraic equations in real time. The proposed learning algorithms for linear least squares (LS), total least squares (TLS) and data least squares (DLS) problems can be considered as modifications and extensions of well known algorithms: the row-action projection-Kaczmarz algorithm and/or the LMS (Adaline) Widrow-Hoff algorithms. The algorithms can be applied to any problem which can be formulated as a linear regression problem. The correctness and high performance of the proposed neural networks are illustrated by extensive computer simulation results.

  11. Temporal compression in episodic memory for real-life events.

    Science.gov (United States)

    Jeunehomme, Olivier; Folville, Adrien; Stawarczyk, David; Van der Linden, Martial; D'Argembeau, Arnaud

    2018-07-01

    Remembering an event typically takes less time than experiencing it, suggesting that episodic memory represents past experience in a temporally compressed way. Little is known, however, about how the continuous flow of real-life events is summarised in memory. Here we investigated the nature and determinants of temporal compression by directly comparing memory contents with the objective timing of events as measured by a wearable camera. We found that episodic memories consist of a succession of moments of prior experience that represent events with varying compression rates, such that the density of retrieved information is modulated by goal processing and perceptual changes. Furthermore, the results showed that temporal compression rates remain relatively stable over one week and increase after a one-month delay, particularly for goal-related events. These data shed new light on temporal compression in episodic memory and suggest that compression rates are adaptively modulated to maintain current goal-relevant information.

  12. Psychosocial stress based on public speech in humans: is there a real life/laboratory setting cross-adaptation?

    Science.gov (United States)

    Jezova, D; Hlavacova, N; Dicko, I; Solarikova, P; Brezina, I

    2016-07-01

    Repeated or chronic exposure to stressors is associated with changes in neuroendocrine responses depending on the type, intensity, number and frequency of stress exposure as well as previous stress experience. The aim of the study was to test the hypothesis that salivary cortisol and cardiovascular responses to real-life psychosocial stressors related to public performance can cross-adapt with responses to psychosocial stress induced by public speech under laboratory setting. The sample consisted of 22 healthy male volunteers, which were either actors, more precisely students of dramatic arts or non-actors, students of other fields. The stress task consisted of 15 min anticipatory preparation phase and 15 min of public speech on an emotionally charged topic. The actors, who were accustomed to public speaking, responded with a rise in salivary cortisol as well as blood pressure to laboratory public speech. The values of salivary cortisol, systolic blood pressure and state anxiety were lower in actors compared to non-actors. Unlike non-actors, subjects with experience in public speaking did not show stress-induced rise in the heart rate. Evaluation of personality traits revealed that actors scored significantly higher in extraversion than the subjects in the non-actor group. In conclusion, neuroendocrine responses to real-life stressors in actors can partially cross-adapt with responses to psychosocial stress under laboratory setting. The most evident adaptation was at the level of heart rate responses. The public speech tasks may be of help in evaluation of the ability to cope with stress in real life in artists by simple laboratory testing.

  13. Composite Differential Evolution with Modified Oracle Penalty Method for Constrained Optimization Problems

    Directory of Open Access Journals (Sweden)

    Minggang Dong

    2014-01-01

    Full Text Available Motivated by recent advancements in differential evolution and constraints handling methods, this paper presents a novel modified oracle penalty function-based composite differential evolution (MOCoDE for constrained optimization problems (COPs. More specifically, the original oracle penalty function approach is modified so as to satisfy the optimization criterion of COPs; then the modified oracle penalty function is incorporated in composite DE. Furthermore, in order to solve more complex COPs with discrete, integer, or binary variables, a discrete variable handling technique is introduced into MOCoDE to solve complex COPs with mix variables. This method is assessed on eleven constrained optimization benchmark functions and seven well-studied engineering problems in real life. Experimental results demonstrate that MOCoDE achieves competitive performance with respect to some other state-of-the-art approaches in constrained optimization evolutionary algorithms. Moreover, the strengths of the proposed method include few parameters and its ease of implementation, rendering it applicable to real life. Therefore, MOCoDE can be an efficient alternative to solving constrained optimization problems.

  14. Health related quality of life, cognitive functioning and behaviour problems in children

    NARCIS (Netherlands)

    Vrijmoet-Wiersma, C.M.J.; Kooloos, V.M.; Koopman, H.M.; Kolk, A.M.; van der Laan, I.; Grootenhuis, M.A.; Egeler, R.M.

    2009-01-01

    Background: This study was designed to evaluate generic and disease-specific health-related quality of life (HRQoL), cognitive functioning and behaviour problems of children with Langerhans Cell Histiocytosis (LCH). Furthermore, we investigated which medical determinants and social demographic

  15. Students without Borders: Global Collaborative Learning Connects School to the Real World

    Science.gov (United States)

    Bickley, Mali; Carleton, Jim

    2009-01-01

    Kids can't help but get engaged when they're collaborating with peers across the globe to solve real-life problems. Global collaborative learning is about connecting students in communities of learners around the world so they can work together on projects that make a difference locally and globally. It is about building relationships and…

  16. Holistic Mathematics Instruction: Interactive Problem Solving and Real Life Situations Help Learners Understand Math Concepts.

    Science.gov (United States)

    Archambeault, Betty

    1993-01-01

    Holistic math focuses on problem solving with numbers and concepts. Whole math activities for adults include shopping for groceries, eating in restaurants, buying gas, taking medicine, measuring a room, estimating servings, and compiling a family cookbook. (SK)

  17. Mental Health Problems in Adults with Down Syndrome and Their Association with Life Circumstances

    Science.gov (United States)

    Mallardo, Mariarosa; Cuskelly, Monica; White, Paul; Jobling, Anne

    2014-01-01

    This study focused on current life circumstances, previous life events, and engagement with productive and enjoyable activities. It examined the association of these variables with mental health problems and mood in a cohort of young adults with Down syndrome. Participants were 49 adults with Down syndrome (age range 20-31 years) and their…

  18. Towards a Framework of Using Knowledge Tools for Teaching by Solving Problems in Technology-Enhanced Learning Environment

    Science.gov (United States)

    Kostousov, Sergei; Kudryavtsev, Dmitry

    2017-01-01

    Problem solving is a critical competency for modern world and also an effective way of learning. Education should not only transfer domain-specific knowledge to students, but also prepare them to solve real-life problems--to apply knowledge from one or several domains within specific situation. Problem solving as teaching tool is known for a long…

  19. Strategies of solving arithmetic word problems in students with learning difficulties in mathematics

    OpenAIRE

    Kalan, Marko

    2015-01-01

    Problem solving as an important skill is, beside arithmetic, measure and algebra, included in standards of school mathematics (National Council of Teachers of Mathematics) (NCTM, 2000) and needed as a necessary skill for successfulness in science, technology, engineering and mathematics (STEM) (National Mathematics Advisory Panel, 2008). Since solving of human problems is connected to the real life, the arithmetic word problems (in short AWP) are an important kind of mathematics tasks in scho...

  20. Personal attitudes toward time: The relationship between temporal focus, space-time mappings and real life experiences.

    Science.gov (United States)

    Li, Heng; Cao, Yu

    2017-06-01

    What influences how people implicitly associate "past" and "future" with "front" and "back?" Whereas previous research has shown that cultural attitudes toward time play a role in modulating space-time mappings in people's mental models (de la Fuente, Santiago, Román, Dumitrache & Casasanto, 2014), we investigated real life experiences as potential additional influences on these implicit associations. Participants within the same single culture, who are engaged in different intermediate-term educational experiences (Study 1), long-term living experiences (Study 2), and short-term visiting experiences (Study 3), showed their distinct differences in temporal focus, thereby influencing their implicit spatializations of time. Results across samples suggest that personal attitudes toward time related to real life experiences may influence people's space-time mappings. The findings we report on shed further light on the high flexibility of human conceptualization system. While culture may exert an important influence on temporal focus, a person's conceptualization of time may be attributed to a culmination of factors. © 2017 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  1. [Study on the correlation between adolescents' emotional and behavioral problems and life events].

    Science.gov (United States)

    Huang, Xue-zhu; Guo, Lan-ting; Tang, Guang-zheng

    2006-03-01

    To study the life events which are correlated with adolescent's emotion and behavior problems, and to provide evidence for clinicians and school staff to develop intervention for those problems. Youth's Self Report (YSR) and Adolescent Self-Rating Life Events Check List (ASLEC) were used to assess adolescent's emotional and behavioral problems and life events by 'spot' study. The referred group consisted of 585 patients from 11 to 18 years old in a Mental Health Centre of West China Hospital of Sichuan University from July in 2002 to March in 2004. Level of IQ was above 5th grade of primary school among the study subjects who were willing to fill in the YSR and ASLEC. The non-referred group was selected in a 1280 students cluster-sample from the schools of Chengdu city, whose sex, age and father's career were matched with the referred group. Variance inflation factor (VIF) was used to verify that there was no collinearity to each other in the 6 factors of ASLEC: interpersonal relationship, learning pressure, being punished, losing good adaptation and other. Linear stepwise regression was adopted. The YSR scores in referred group were higher than those in non-referred group, and the referred group had more emotional and behavioral problems than the non-referred one. Partial correlations ranged from 0.124 to 0.418 in referred group, and from 0.104 to 0.388 in non-referred group. Unsatisfied interpersonal relationship, heavy learning pressure, having been punished and poor adaptation were likely to increase the risk of youth's emotional and behavioral problems. More attention should be paid to help adolescents in the following areas: solving intrapersonal affairs, relieving pressure from learning, avoiding punishment, and improving ability to fit themselves to their surroundings.

  2. The Inverse Contagion Problem (ICP) vs.. Predicting site contagion in real time, when network links are not observable

    Science.gov (United States)

    Mushkin, I.; Solomon, S.

    2017-10-01

    We study the inverse contagion problem (ICP). As opposed to the direct contagion problem, in which the network structure is known and the question is when each node will be contaminated, in the inverse problem the links of the network are unknown but a sequence of contagion histories (the times when each node was contaminated) is observed. We consider two versions of the ICP: The strong problem (SICP), which is the reconstruction of the network and has been studied before, and the weak problem (WICP), which requires "only" the prediction (at each time step) of the nodes that will be contaminated at the next time step (this is often the real life situation in which a contagion is observed and predictions are made in real time). Moreover, our focus is on analyzing the increasing accuracy of the solution, as a function of the number of contagion histories already observed. For simplicity, we discuss the simplest (deterministic and synchronous) contagion dynamics and the simplest solution algorithm, which we have applied to different network types. The main result of this paper is that the complex problem of the convergence of the ICP for a network can be reduced to an individual property of pairs of nodes: the "false link difficulty". By definition, given a pair of unlinked nodes i and j, the difficulty of the false link (i,j) is the probability that in a random contagion history, the nodes i and j are not contaminated at the same time step (or at consecutive time steps). In other words, the "false link difficulty" of a non-existing network link is the probability that the observations during a random contagion history would not rule out that link. This probability is relatively straightforward to calculate, and in most instances relies only on the relative positions of the two nodes (i,j) and not on the entire network structure. We have observed the distribution of false link difficulty for various network types, estimated it theoretically and confronted it

  3. Managing in the Virtual World: How Second Life is Rewriting the Rules of "Real Life" Business

    Science.gov (United States)

    Wyld, David C.

    In this paper, we will explore the growth of virtual worlds - one of the most exciting and fast-growing concepts in the Web 2.0 era. We will see that while there has been significant growth across all demographic groups, online gaming in MMOGs (Massively Multiplayer Online Games) are finding particular appeal in today's youth - the so-called "digital native" generation. We then overview the today's virtual world marketplace, both in the youth and adult-oriented markets. Second Life is emerging as the most important virtual world today, due to the intense interest amongst both large organizations and individual entrepreneurs to conduct real business in the virtual environment. Due to its prominence today and its forecasted growth over the next decade, we take a look at the unscripted world of Second Life, examining the corporate presence in-world, as well as the economic, technical, legal, ethical and security issues involved for companies doing business in the virtual world. In conclusion, we present an analysis of where we stand in terms of virtual world development today and a projection of where we will be heading in the near future. Finally, we present advice to management practitioners and academicians on how to learn about virtual worlds and explore the world of opportunities in them.

  4. Designing and using multiple-possibility physics problems in physics courses

    Science.gov (United States)

    Shekoyan, Vazgen

    2012-02-01

    One important aspect of physics instruction is helping students develop better problem solving expertise. Besides enhancing the content knowledge, problems help students develop different cognitive abilities and skills. This presentation focuses on multiple-possibility problems (alternatively called ill-structured problems). These problems are different from traditional ``end of chapter'' single-possibility problems. They do not have one right answer and thus the student has to examine different possibilities, assumptions and evaluate the outcomes. To solve such problems one has to engage in a cognitive monitoring called epistemic cognition. It is an important part of thinking in real life. Physicists routinely use epistemic cognition when they solve problems. I have explored the instructional value of using such problems in introductory physics courses.

  5. Effects of an explicit problem-solving skills training program using a metacomponential approach for outpatients with acquired brain injury.

    Science.gov (United States)

    Fong, Kenneth N K; Howie, Dorothy R

    2009-01-01

    We investigated the effects of an explicit problem-solving skills training program using a metacomponential approach with 33 outpatients with moderate acquired brain injury, in the Hong Kong context. We compared an experimental training intervention with this explicit problem-solving approach, which taught metacomponential strategies, with a conventional cognitive training approach that did not have this explicit metacognitive training. We found significant advantages for the experimental group on the Metacomponential Interview measure in association with the explicit metacomponential training, but transfer to the real-life problem-solving measures was not evidenced in statistically significant findings. Small sample size, limited time of intervention, and some limitations with these tools may have been contributing factors to these results. The training program was demonstrated to have a significantly greater effect than the conventional training approach on metacomponential functioning and the component of problem representation. However, these benefits were not transferable to real-life situations.

  6. Overvoltage Protection of Large Power Transformers - A Real-Life Study Case

    DEFF Research Database (Denmark)

    Bak, Claus Leth; Einarsdottir, K. E.; Andresson, E.

    2008-01-01

    This paper demonstrates the results from a detailed study of the overvoltage protection of a particular 400/150-kV 400-MVA power transformer. The work presented here is based on a real-life power system substation design and data and initiated by Danish TSO Energinet.dk as a consequence of serious...... transformer overvoltage damage. A simulation model for the entire system consisting of overhead line, transformer, surge arrester, and earth grid has been created in PSCAD/EMTDC. The main focus has been put on the earth grid, which has been submodeled in detail in MATLAB using an electromagnetic transient...... exceeded. It is clearly illustrated that the transient performance of the earth grid plays an important role in the overall overvoltage protection system design....

  7. Solutions to time variant problems of real-time expert systems

    Science.gov (United States)

    Yeh, Show-Way; Wu, Chuan-Lin; Hung, Chaw-Kwei

    1988-01-01

    Real-time expert systems for monitoring and control are driven by input data which changes with time. One of the subtle problems of this field is the propagation of time variant problems from rule to rule. This propagation problem is even complicated under a multiprogramming environment where the expert system may issue test commands to the system to get data and to access time consuming devices to retrieve data for concurrent reasoning. Two approaches are used to handle the flood of input data. Snapshots can be taken to freeze the system from time to time. The expert system treats the system as a stationary one and traces changes by comparing consecutive snapshots. In the other approach, when an input is available, the rules associated with it are evaluated. For both approaches, if the premise condition of a fired rule is changed to being false, the downstream rules should be deactivated. If the status change is due to disappearance of a transient problem, actions taken by the fired downstream rules which are no longer true may need to be undone. If a downstream rule is being evaluated, it should not be fired. Three mechanisms for solving this problem are discussed: tracing, backward checking, and censor setting. In the forward tracing mechanism, when the premise conditions of a fired rule become false, the premise conditions of downstream rules which have been fired or are being evaluated due to the firing of that rule are reevaluated. A tree with its root at the rule being deactivated is traversed. In the backward checking mechanism, when a rule is being fired, the expert system checks back on the premise conditions of the upstream rules that result in evaluation of the rule to see whether it should be fired. The root of the tree being traversed is the rule being fired. In the censor setting mechanism, when a rule is to be evaluated, a censor is constructed based on the premise conditions of the upstream rules and the censor is evaluated just before the rule is

  8. Real Time Revisited

    Science.gov (United States)

    Allen, Phillip G.

    1985-12-01

    The call for abolishing photo reconnaissance in favor of real time is once more being heard. Ten years ago the same cries were being heard with the introduction of the Charge Coupled Device (CCD). The real time system problems that existed then and stopped real time proliferation have not been solved. The lack of an organized program by either DoD or industry has hampered any efforts to solve the problems, and as such, very little has happened in real time in the last ten years. Real time is not a replacement for photo, just as photo is not a replacement for infra-red or radar. Operational real time sensors can be designed only after their role has been defined and improvements made to the weak links in the system. Plodding ahead on a real time reconnaissance suite without benefit of evaluation of utility will allow this same paper to be used ten years from now.

  9. Hearts and Minds: Real-Life Cardiotoxicity With Clozapine in Psychosis.

    Science.gov (United States)

    Joy, George; Whiskey, Eromona; Bolstridge, Mark; Porras-Segovia, Alejandro; McDonagh, Theresa A; Plymen, Carla M; Shergill, Sukhi S

    2017-12-01

    Schizophrenia has a 1% prevalence in the population; 30% of these patients are treatment refractory. Clozapine is the only drug licensed to treat treatment refractory psychosis, but concerns about potential adverse effects result in only a proportion of eligible patients being treated. Although a well-documented neutropenia risk is mitigated by routine blood testing, cardiac toxicity is a commonly cited reason to discontinue clozapine treatment. However, there is little data on the real-life cardiac outcomes in those receiving clozapine treatment. Retrospective review of electrocardiogram, echocardiogram, and clinical outcomes in 39 inpatients with treatment-refractory schizophrenia, treated with clozapine and other antipsychotic medication, referred for cardiology opinion. Commonest reasons for referral were development of left ventricular (LV) impairment or sinus tachycardia with normal LV function. Patients were reviewed by a range of cardiologists, receiving varied interventions.Median LV ejection fraction in the clozapine group was normal (52%). Serial echocardiograms demonstrated that clozapine-treated patients with LV impairment had no change in LV ejection fraction over a 4-month follow-up. Left ventricular ejection fraction did not differ between patients treated with clozapine and other antipsychotics. However, over an 11-year follow-up period, 48% of patients had discontinued clozapine treatment. This naturalistic study demonstrates that clozapine is not associated with significant cardiac mortality or morbidity. There is a real need for multidisciplinary working between specialist cardiologists and psychiatrists caring for these complex patients to facilitate optimal long-term physical and mental health outcomes.

  10. Schizophrenia, Narrative, and Neurocognition: The Utility of Life-Stories in Understanding Social Problem-Solving Skills.

    Science.gov (United States)

    Moe, Aubrey M; Breitborde, Nicholas J K; Bourassa, Kyle J; Gallagher, Colin J; Shakeel, Mohammed K; Docherty, Nancy M

    2018-01-22

    Schizophrenia researchers have focused on phenomenological aspects of the disorder to better understand its underlying nature. In particular, development of personal narratives-that is, the complexity with which people form, organize, and articulate their "life stories"-has recently been investigated in individuals with schizophrenia. However, less is known about how aspects of narrative relate to indicators of neurocognitive and social functioning. The objective of the present study was to investigate the association of linguistic complexity of life-story narratives to measures of cognitive and social problem-solving abilities among people with schizophrenia. Thirty-two individuals with a diagnosis of schizophrenia completed a research battery consisting of clinical interviews, a life-story narrative, neurocognitive testing, and a measure assessing multiple aspects of social problem solving. Narrative interviews were assessed for linguistic complexity using computerized technology. The results indicate differential relationships of linguistic complexity and neurocognition to domains of social problem-solving skills. More specifically, although neurocognition predicted how well one could both describe and enact a solution to a social problem, linguistic complexity alone was associated with accurately recognizing that a social problem had occurred. In addition, linguistic complexity appears to be a cognitive factor that is discernible from other broader measures of neurocognition. Linguistic complexity may be more relevant in understanding earlier steps of the social problem-solving process than more traditional, broad measures of cognition, and thus is relevant in conceptualizing treatment targets. These findings also support the relevance of developing narrative-focused psychotherapies. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  11. Absent yet Present: On the Paradoxical Nature of Characters in Nabokov’s The Real Life of Sebastian Knight

    Directory of Open Access Journals (Sweden)

    Irina Marchesini

    2016-11-01

    Full Text Available The present research is focused on the theme of absence, an area of inquiry that might seem dominant in the field of Nabokov Studies. The analysis, which concentrates in particular on the key figures of the novel The Real Life of Sebastian Knight (1941, notably the narrator V. and the poet Sebastian Knight, interprets the characters’ construction through the paradigm of absence. Arguably, the construction of characters in The Real Life of Sebastian Knight is paradoxical: absence constitutes their essence at a core level, as it often happens in the context of the self-conscious genre. Moreover, absence plays a key role in characters’ design, linking them to all Nabokovian novels. However, despite their innermost ‘flatness’, to use Edward M. Forster’s terminology, they still appear to be ‘round’, i.e. plausible, mimetic figures.

  12. Removal of Dissolved Silica using Calcinated Hydrotalcite in Real-life Applications.

    Energy Technology Data Exchange (ETDEWEB)

    Sasan, Koroush [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brady, Patrick Vane. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Krumhansl, James L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Nenoff, Tina M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sasan, Koroush [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sasan, Koroush [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-09-01

    Water shortages are a growing global problem. Reclamation of industrial and municipal wastewater will be necessary in order to mitigate water scarcity. However, many operational challenges, such as silica scaling, prevent large scale water reuse. Previously, our team at Sandia has demonstrated the use of selective ion exchange materials, such as calcinated hydrotalcite (HTC, (Mg 6 Al 2 (OH) 16 (CO 3 )*4H 2 O)), for the low cost removal of silica from synthetic cooling tower water. However, it is not currently know if calcinated HTC has similar capabilities in realistic applications. The purpose of this study was to investigate the ability of calcinated HTC to remove silica from real cooling tower water. This was investigated under both batch and continuous conditions, and in the presence of competing ions. It was determined that calcinated HTC behaved similarly in real and synthetic cooling tower water; the HTC is highly selective for the silica even in the presence of competing cations. Therefore, the data concludes that calcinated HTC is a viable anti-scaling pretreatment for the reuse of industrial wastewaters.

  13. Evaluation of RPL-compliant routing solutions in real-life WSNs

    Directory of Open Access Journals (Sweden)

    Zahariadis Theodore

    2016-01-01

    Full Text Available Wireless Sensor Networks (WSN applications continue to expand and already cover almost all our daily activities improving from security and environmental efficiency to gaming experience. The diverse applications running on top of WSNs have led to the design of an immense number of routing protocols. Few years ago, the IETF standardized the IPv6 routing protocol for low-power and lossy networks (RPL which is based on routing metrics to build communication paths between a source and the destination node. While significant efforts have focused on the design of routing metrics that satisfy the various applications, limited work has been reported on validating their performance using real-life motes. In this paper, we focus on validating the simulation results (obtained through the JSim simulator using TelosB motes for a set of routing metrics that have been proposed in our previous articles.

  14. Does a 20-week aerobic exercise training programme increase our capabilities to buffer real-life stressors? A randomized, controlled trial using ambulatory assessment.

    Science.gov (United States)

    von Haaren, Birte; Ottenbacher, Joerg; Muenz, Julia; Neumann, Rainer; Boes, Klaus; Ebner-Priemer, Ulrich

    2016-02-01

    The cross-stressor adaptation hypothesis suggests that regular exercise leads to adaptations in the stress response systems that induce decreased physiological responses to psychological stressors. Even though an exercise intervention to buffer the detrimental effects of psychological stressors on health might be of utmost importance, empirical evidence is mixed. This may be explained by the use of cross-sectional designs and non-personally relevant stressors. Using a randomized controlled trial, we hypothesized that a 20-week aerobic exercise training does reduce physiological stress responses to psychological real-life stressors in sedentary students. Sixty-one students were randomized to either a control group or an exercise training group. The academic examination period (end of the semester) served as a real-life stressor. We used ambulatory assessment methods to assess physiological stress reactivity of the autonomic nervous system (heart rate variability: LF/HF, RMSSD), physical activity and perceived stress during 2 days of everyday life and multilevel models for data analyses. Aerobic capacity (VO2max) was assessed pre- and post-intervention via cardiopulmonary exercise testing to analyze the effectiveness of the intervention. During real-life stressors, the exercise training group showed significantly reduced LF/HF (β = -0.15, t = -2.59, p = .01) and increased RMSSD (β = 0.15, t = 2.34, p = .02) compared to the control group. Using a randomized controlled trial and a real-life stressor, we could show that exercise appears to be a useful preventive strategy to buffer the effects of stress on the autonomic nervous system, which might result into detrimental health outcomes.

  15. Using Real-Worldness and Cultural Difference to Enhance Student Learning in a Foundation Phase Life Skills Module

    Science.gov (United States)

    Koen, Mariette; Ebrahim, Hasina Banu

    2013-01-01

    Our aim was to explore how real-world experience, inclusive of engagement with cultural differences, influences the quality of students' learning in a Life Skills module in pre-service Foundation Phase teacher education. The study was conducted with 147 students in their final year of the Bachelor of Education (Foundation Phase specialisation), at…

  16. ADOLESCENTS WITH BEHAVIORAL PROBLEMS: PERSONALITY, QUALITY OF LIFE AND SOCIAL HEALTH CARE

    Directory of Open Access Journals (Sweden)

    S. Ya. Volgina

    2013-01-01

    Full Text Available Deviant behavior of adolescents is a serious social problem in today's society because of the significant prevalence of this phenomenon. Authors present the results of the study of adolescents with behavioral problems. Aim: optimization of medical and social care for adolescents with behavioral problems. Patients and methods: the authors studied the incidence of this condition among children aged from 15 to 17 years using the software package «SOC/PEDIATRIA-2». The features of the personality structure of adolescents with deviant behavior were revealed using the adopted Russian short version of MMPI-MINI-MULT. Demographic and social characteristics of the families of adolescents were assessed. SF-36 questionnaire was applied for the quality of life assessment of the studied category. Results: increasing morbidity among adolescents was revealed due to various reasons: economic, medical and social. The study allowed to develop personal characteristics of the criteria in order to timely identify adolescents with accentuated and psychopathological features. The characteristics of quality of life were used as criteria of health care for adolescents with behavioral problems. The measures for the prevention and correction of deviant behavior among adolescents were proposed, including intersectoral integration and active participation of family in the process of rehabilitation. Conclusions: it is necessary to identify adolescents with deviant behavior timely, followed by a set of measures to provide them with health and social care to protect their health.

  17. Numerical simulations of coupled problems in engineering

    CERN Document Server

    2014-01-01

    This book presents and discusses mathematical models, numerical methods and computational techniques used for solving coupled problems in science and engineering. It takes a step forward in the formulation and solution of real-life problems with a multidisciplinary vision, accounting for all of the complex couplings involved in the physical description. Simulation of multifaceted physics problems is a common task in applied research and industry. Often a suitable solver is built by connecting together several single-aspect solvers into a network. In this book, research in various fields was selected for consideration: adaptive methodology for multi-physics solvers, multi-physics phenomena and coupled-field solutions, leading to computationally intensive structural analysis. The strategies which are used to keep these problems computationally affordable are of special interest, and make this an essential book.

  18. New methods for solving a vertex p-center problem with uncertain demand-weighted distance: A real case study

    Directory of Open Access Journals (Sweden)

    Javad Nematian

    2015-04-01

    Full Text Available Vertex and p-center problems are two well-known types of the center problem. In this paper, a p-center problem with uncertain demand-weighted distance will be introduced in which the demands are considered as fuzzy random variables (FRVs and the objective of the problem is to minimize the maximum distance between a node and its nearest facility. Then, by introducing new methods, the proposed problem is converted to deterministic integer programming (IP problems where these methods will be obtained through the implementation of the possibility theory and fuzzy random chance-constrained programming (FRCCP. Finally, the proposed methods are applied for locating bicycle stations in the city of Tabriz in Iran as a real case study. The computational results of our study show that these methods can be implemented for the center problem with uncertain frameworks.

  19. Differences between clinical "snap-shot" and "real-life" assessments of lumbar spine alignment and motion - What is the "real" lumbar lordosis of a human being?

    Science.gov (United States)

    Dreischarf, Marcel; Pries, Esther; Bashkuev, Maxim; Putzier, Michael; Schmidt, Hendrik

    2016-03-21

    The individual lumbar lordosis and lumbar motion have been identified to play an important role in pathogenesis of low back pain and are essential references for preoperative planning and postoperative evaluation. The clinical "gold-standard" for measuring lumbar lordosis and its motion are radiological "snap-shots" taken while standing and during upper-body flexion and extension. The extent to which these clinically assessed values characterise lumbar alignment and its motion in daily life merits discussion. A non-invasive measurement-system was employed to measure lumbar lordosis and lumbar motion in 208 volunteers (age: 20-74yrs; ♀/♂: 115/93). For an initial short-term measurement, comparable with the clinical "snap-shot", lumbar lordosis and its motion were assessed while standing and during flexion and extension. Subsequently, volunteers were released to their daily lives while wearing the device, and measurements were performed during the following 24h. The average lumbar lordosis during 24h (8.0°) differed significantly from the standardised measurement while standing (33.3°). Ranges of motion were significantly different throughout the day compared to standing measurements. The influence of the factors age and gender on lordosis and its motion resulted in conflicting results between long- and short-term-measurements. In conclusion, results of short-term examinations differ considerably from the average values during real-life. These findings might be important for surgical planning and increase the awareness of the biomechanical challenges that spinal structures and implants face in real-life. Furthermore, long-term assessments of spinal alignment and motion during daily life can provide valid data on spinal function and can reveal the importance of influential factors. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Simulation Optimization for Transportation System: A Real Case Application

    Directory of Open Access Journals (Sweden)

    Muhammet Enes Akpınar

    2017-02-01

    Full Text Available Simulation applications help decision makers to give right decisions to eliminate some problems such as: create a new firm, need some changes inside a factory; improve the process of a hospital etc. In this engineering simulation study, there are two points which are used by students to arrive at the University. Initial point is the train station and the final point is the arrival point. Students’ transportation is provided with buses. The main problem is to decide the number of buses by taking number of student into consideration. To be able to solve this real-life application PROMODEL pack software is used.

  1. The use of questionnaires in colour research in real-life settings : In search of validity and methodological pitfalls

    NARCIS (Netherlands)

    Bakker, I.C.; van der Voordt, Theo; Vink, P.; de Boon, J

    2014-01-01

    This research discusses the validity of applying questionnaires in colour research in real life settings.
    In the literature the conclusions concerning the influences of colours on human performance and well-being are often conflicting. This can be caused by the artificial setting of the test

  2. Solving Optimization Problems via Vortex Optimization Algorithm and Cognitive Development Optimization Algorithm

    OpenAIRE

    Ahmet Demir; Utku kose

    2017-01-01

    In the fields which require finding the most appropriate value, optimization became a vital approach to employ effective solutions. With the use of optimization techniques, many different fields in the modern life have found solutions to their real-world based problems. In this context, classical optimization techniques have had an important popularity. But after a while, more advanced optimization problems required the use of more effective techniques. At this point, Computer Science took an...

  3. EDITORIAL Wireless sensor networks: design for real-life deployment and deployment experiences Wireless sensor networks: design for real-life deployment and deployment experiences

    Science.gov (United States)

    Gaura, Elena; Roedig, Utz; Brusey, James

    2010-12-01

    modalities and (iv) system solutions with high end-user added value and cost benefits. The common thread is deployment and deployment evaluation. In particular, satisfaction of application requirements, involvement of the end-user in the design and deployment process, satisfactory system performance and user acceptance are concerns addressed in many of the contributions. The contributions form a valuable set, which help to identify the priorities for research in this burgeoning area: Robust, reliable and efficient data collection in embedded wireless multi-hop networks are essential elements in creating a true deploy-and-forget user experience. Maintaining full connectivity within a WSN, in a real world environment populated by other WSNs, WiFi networks or Bluetooth devices that constitute sources of interference is a key element in any application, but more so for those that are safety-critical, such as disaster response. Awareness of the effects of wireless channel, physical position and line-of-sight on received signal strength in real-world, outdoor environments will shape the design of many outdoor applications. Thus, the quantification of such effects is valuable knowledge for designers. Sensors' failure detection, scalability and commercialization are common challenges in many long-term monitoring applications; transferable solutions are evidenced here in the context of pollutant detection and water quality. Innovative, alternative thinking is often needed to achieve the desired long-lived networks when power-hungry sensors are foreseen components; in some instances, the very problems of wireless technology, such as RF irregularity, can be transformed into advantages. The importance of an iterative design and evaluation methodology—from analysis to simulation to real-life deployment—should be well understood by all WSN developers. The value of this is highlighted in the context of a challenging WPAN video-surveillance application based on a novel Nomadic Access

  4. The Home Care Crew Scheduling Problem

    DEFF Research Database (Denmark)

    Rasmussen, Matias Sevel; Justesen, Tor

    In the Home Care Crew Scheduling Problem (HCCSP) a staff of caretakers has to be assigned a number of visits, such that the total number of assigned visits is maximised. The visits have different locations and positions in time, and travelling time and time windows must be respected. The challenge...... when assigning visits to caretakers lies in the existence of soft constraints and indeed also in temporal dependencies between the starting times of visits. Most former approaches to solving the HCCSP involve the use of heuristic methods. Here we develop an exact branch-and-price algorithm that uses...... clustering of the visits based on the problem structure. The algorithm is tested on real-life problem instances and we obtain solutions that are better than current practice in all cases....

  5. The Geometric Construction Abilities Of Gifted Students In Solving Real - World Problems: A Case From Turkey

    Directory of Open Access Journals (Sweden)

    Avni YILDIZ

    2016-10-01

    Full Text Available Geometric constructions have already been of interest to mathematicians. However, studies on geometric construction are not adequate in the relevant literature. Moreover, these studies generally focus on how secondary school gifted students solve non-routine mathematical problems. The present study aims to examine the geometric construction abilities of ninth-grade (15 years old gifted students in solving real-world geometry problems; thus a case study was conducted. Six gifted students participated in the study. The data consisted of voice records, solutions, and models made by the students on the GeoGebra screen. Results indicate that gifted students use their previous knowledge effectively during the process of geometric construction. They modeled the situations available in the problems through using mathematical concepts and the software in coordination. Therefore, it is evident that gifted students think more creatively while solving problems using GeoGebra.

  6. Numerical simulation of a cabin ventilation subsystem in a space station oriented real-time system

    Directory of Open Access Journals (Sweden)

    Zezheng QIU

    2017-12-01

    Full Text Available An environment control and life support system (ECLSS is an important system in a space station. The ECLSS is a typical complex system, and the real-time simulation technology can help to accelerate its research process by using distributed hardware in a loop simulation system. An implicit fixed time step numerical integration method is recommended for a real-time simulation system with time-varying parameters. However, its computational efficiency is too low to satisfy the real-time data interaction, especially for the complex ECLSS system running on a PC cluster. The instability problem of an explicit method strongly limits its application in the ECLSS real-time simulation although it has a high computational efficiency. This paper proposes an improved numerical simulation method to overcome the instability problem based on the explicit Euler method. A temperature and humidity control subsystem (THCS is firstly established, and its numerical stability is analyzed by using the eigenvalue estimation theory. Furthermore, an adaptive operator is proposed to avoid the potential instability problem. The stability and accuracy of the proposed method are investigated carefully. Simulation results show that this proposed method can provide a good way for some complex time-variant systems to run their real-time simulation on a PC cluster. Keywords: Numerical integration method, Real-time simulation, Stability, THCS, Time-variant system

  7. Performance Evaluation of State of the Art Systems for Physical Activity Classification of Older Subjects Using Inertial Sensors in a Real Life Scenario: A Benchmark Study.

    Science.gov (United States)

    Awais, Muhammad; Palmerini, Luca; Bourke, Alan K; Ihlen, Espen A F; Helbostad, Jorunn L; Chiari, Lorenzo

    2016-12-11

    The popularity of using wearable inertial sensors for physical activity classification has dramatically increased in the last decade due to their versatility, low form factor, and low power requirements. Consequently, various systems have been developed to automatically classify daily life activities. However, the scope and implementation of such systems is limited to laboratory-based investigations. Furthermore, these systems are not directly comparable, due to the large diversity in their design (e.g., number of sensors, placement of sensors, data collection environments, data processing techniques, features set, classifiers, cross-validation methods). Hence, the aim of this study is to propose a fair and unbiased benchmark for the field-based validation of three existing systems, highlighting the gap between laboratory and real-life conditions. For this purpose, three representative state-of-the-art systems are chosen and implemented to classify the physical activities of twenty older subjects (76.4 ± 5.6 years). The performance in classifying four basic activities of daily life (sitting, standing, walking, and lying) is analyzed in controlled and free living conditions. To observe the performance of laboratory-based systems in field-based conditions, we trained the activity classification systems using data recorded in a laboratory environment and tested them in real-life conditions in the field. The findings show that the performance of all systems trained with data in the laboratory setting highly deteriorates when tested in real-life conditions, thus highlighting the need to train and test the classification systems in the real-life setting. Moreover, we tested the sensitivity of chosen systems to window size (from 1 s to 10 s) suggesting that overall accuracy decreases with increasing window size. Finally, to evaluate the impact of the number of sensors on the performance, chosen systems are modified considering only the sensing unit worn at the lower back

  8. Performance Evaluation of State of the Art Systems for Physical Activity Classification of Older Subjects Using Inertial Sensors in a Real Life Scenario: A Benchmark Study

    Directory of Open Access Journals (Sweden)

    Muhammad Awais

    2016-12-01

    Full Text Available The popularity of using wearable inertial sensors for physical activity classification has dramatically increased in the last decade due to their versatility, low form factor, and low power requirements. Consequently, various systems have been developed to automatically classify daily life activities. However, the scope and implementation of such systems is limited to laboratory-based investigations. Furthermore, these systems are not directly comparable, due to the large diversity in their design (e.g., number of sensors, placement of sensors, data collection environments, data processing techniques, features set, classifiers, cross-validation methods. Hence, the aim of this study is to propose a fair and unbiased benchmark for the field-based validation of three existing systems, highlighting the gap between laboratory and real-life conditions. For this purpose, three representative state-of-the-art systems are chosen and implemented to classify the physical activities of twenty older subjects (76.4 ± 5.6 years. The performance in classifying four basic activities of daily life (sitting, standing, walking, and lying is analyzed in controlled and free living conditions. To observe the performance of laboratory-based systems in field-based conditions, we trained the activity classification systems using data recorded in a laboratory environment and tested them in real-life conditions in the field. The findings show that the performance of all systems trained with data in the laboratory setting highly deteriorates when tested in real-life conditions, thus highlighting the need to train and test the classification systems in the real-life setting. Moreover, we tested the sensitivity of chosen systems to window size (from 1 s to 10 s suggesting that overall accuracy decreases with increasing window size. Finally, to evaluate the impact of the number of sensors on the performance, chosen systems are modified considering only the sensing unit worn

  9. Exploring Marine Ecosystems with Elementary School Portuguese Children: Inquiry-Based Project Activities Focused on "Real-Life" Contexts

    Science.gov (United States)

    Guilherme, Elsa; Faria, Cláudia; Boaventura, Diana

    2016-01-01

    The purpose of the study was to investigate how young students engage in an inquiry-based project driven by real-life contexts. Elementary school children were engaged in a small inquiry project centred on marine biodiversity and species adaptations. All activities included the exploration of an out-of-school setting as a learning context. A total…

  10. Capacitated arc routing problem and its extensions in waste collection

    International Nuclear Information System (INIS)

    Fadzli, Mohammad; Najwa, Nurul; Luis, Martino

    2015-01-01

    Capacitated arc routing problem (CARP) is the youngest generation of graph theory that focuses on solving the edge/arc routing for optimality. Since many years, operational research devoted to CARP counterpart, known as vehicle routing problem (VRP), which does not fit to several real cases such like waste collection problem and road maintenance. In this paper, we highlighted several extensions of capacitated arc routing problem (CARP) that represents the real-life problem of vehicle operation in waste collection. By purpose, CARP is designed to find a set of routes for vehicles that satisfies all pre-setting constraints in such that all vehicles must start and end at a depot, service a set of demands on edges (or arcs) exactly once without exceeding the capacity, thus the total fleet cost is minimized. We also addressed the differentiation between CARP and VRP in waste collection. Several issues have been discussed including stochastic demands and time window problems in order to show the complexity and importance of CARP in the related industry. A mathematical model of CARP and its new version is presented by considering several factors such like delivery cost, lateness penalty and delivery time

  11. Capacitated arc routing problem and its extensions in waste collection

    Energy Technology Data Exchange (ETDEWEB)

    Fadzli, Mohammad; Najwa, Nurul [Institut Matematik Kejuruteraan, Universiti Malaysia Perlis, Kampus Pauh Putra, 02600 Arau, Perlis (Malaysia); Luis, Martino [Othman Yeop Abdullah Graduate School of Business, Universiti Utara Malaysia, 06010 Sintok, Kedah (Malaysia)

    2015-05-15

    Capacitated arc routing problem (CARP) is the youngest generation of graph theory that focuses on solving the edge/arc routing for optimality. Since many years, operational research devoted to CARP counterpart, known as vehicle routing problem (VRP), which does not fit to several real cases such like waste collection problem and road maintenance. In this paper, we highlighted several extensions of capacitated arc routing problem (CARP) that represents the real-life problem of vehicle operation in waste collection. By purpose, CARP is designed to find a set of routes for vehicles that satisfies all pre-setting constraints in such that all vehicles must start and end at a depot, service a set of demands on edges (or arcs) exactly once without exceeding the capacity, thus the total fleet cost is minimized. We also addressed the differentiation between CARP and VRP in waste collection. Several issues have been discussed including stochastic demands and time window problems in order to show the complexity and importance of CARP in the related industry. A mathematical model of CARP and its new version is presented by considering several factors such like delivery cost, lateness penalty and delivery time.

  12. Effectiveness and tolerability of second-line therapy with vildagliptin vs. other oral agents in type 2 diabetes: A real-life worldwide observational study (EDGE)

    Science.gov (United States)

    Mathieu, C; Barnett, A H; Brath, H; Conget, I; de Castro, J J; Göke, R; Márquez Rodriguez, E; Nilsson, P M; Pagkalos, E; Penfornis, A; Schaper, NC; Wangnoo, S K; Kothny, W; Bader, G

    2013-01-01

    Aim Real-life studies are needed to confirm the clinical relevance of findings from randomised controlled trials (RCTs). This study aimed to assess the effectiveness and tolerability of vildagliptin add-on vs. other oral antihyperglycaemic drugs (OADs) added to OAD monotherapy in a real-life setting, and to explore the advantages and limitations of large-scale ‘pragmatic’ trials. Methods EDGE was a prospective, 1-year, worldwide, real-life observational study in which 2957 physicians reported on the effects of second-line OADs in 45,868 patients with T2DM not reaching glycaemic targets with monotherapy. Physicians could add any OAD, and patients entered either vildagliptin or (pooled) comparator cohort. The primary effectiveness and tolerability end-point (PEP) evaluated proportions of patients decreasing HbA1c > 0.3%, without hypoglycaemia, weight gain, peripheral oedema or gastrointestinal side effects. The most clinically relevant secondary end-point (SEP 3) was attainment of end-point HbA1c vildagliptin-based regimen. The adjusted odds ratio was 1.49 (95% CI: 1.42, 1.55; p vildagliptin-based combination and by 23% of those receiving comparator combinations. The adjusted odds ratio was 1.96 (95% CI: 1.85, 2.07; p vildagliptin and other OADs were consistent with previous data. Conclusion EDGE demonstrates that in a ‘real-life’ setting, vildagliptin as second OAD can lower HbA1c to target without well-recognised OAD side effects, more frequently than comparator OADs. In addition, EDGE illustrates that conducting large-scale, prospective, real-life studies poses challenges but yields valuable clinical information complementary to RCTs. PMID:23961850

  13. On Wigner's problem, computability theory, and the definition of life

    International Nuclear Information System (INIS)

    Swain, J.

    1998-01-01

    In 1961, Eugene Wigner presented a clever argument that in a world which is adequately described by quantum mechanics, self-reproducing systems in general, and perhaps life in particular, would be incredibly improbable. The problem and some attempts at its solution are examined, and a new solution is presented based on computability theory. In particular, it is shown that computability theory provides limits on what can be known about a system in addition to those which arise from quantum mechanics. (author)

  14. A Branch and Cut algorithm for the container shipping network design problem

    DEFF Research Database (Denmark)

    Reinhardt, Line Blander; Pisinger, David

    2012-01-01

    The network design problem in liner shipping is of increasing importance in a strongly competitive market where potential cost reductions can influence market share and profits significantly. In this paper the network design and fleet assignment problems are combined into a mixed integer linear...... programming model minimizing the overall cost. To better reflect the real-life situation we take into account the cost of transhipment, a heterogeneous fleet, route dependant capacities, and butterfly routes. To the best of our knowledge it is the first time an exact solution method to the problem considers...

  15. A granular tabu search algorithm for a real case study of a vehicle routing problem with a heterogeneous fleet and time windows

    Directory of Open Access Journals (Sweden)

    Jose Bernal

    2017-10-01

    Full Text Available Purpose: We consider a real case study of a vehicle routing problem with a heterogeneous fleet and time windows (HFVRPTW for a franchise company bottling Coca-Cola products in Colombia. This study aims to determine the routes to be performed to fulfill the demand of the customers by using a heterogeneous fleet and considering soft time windows. The objective is to minimize the distance traveled by the performed routes. Design/methodology/approach: We propose a two-phase heuristic algorithm. In the proposed approach, after an initial phase (first phase, a granular tabu search is applied during the improvement phase (second phase. Two additional procedures are considered to help that the algorithm could escape from local optimum, given that during a given number of iterations there has been no improvement. Findings: Computational experiments on real instances show that the proposed algorithm is able to obtain high-quality solutions within a short computing time compared to the results found by the software that the company currently uses to plan the daily routes. Originality/value: We propose a novel metaheuristic algorithm for solving a real routing problem by considering heterogeneous fleet and time windows. The efficiency of the proposed approach has been tested on real instances, and the computational experiments shown its applicability and performance for solving NP-Hard Problems related with routing problems with similar characteristics. The proposed algorithm was able to improve some of the current solutions applied by the company by reducing the route length and the number of vehicles.

  16. Design Optimization of Multi-Cluster Embedded Systems for Real-Time Applications

    DEFF Research Database (Denmark)

    Pop, Paul; Eles, Petru; Peng, Zebo

    2004-01-01

    We present an approach to design optimization of multi-cluster embedded systems consisting of time-triggered and event-triggered clusters, interconnected via gateways. In this paper, we address design problems which are characteristic to multi-clusters: partitioning of the system functionality...... into time-triggered and event-triggered domains, process mapping, and the optimization of parameters corresponding to the communication protocol. We present several heuristics for solving these problems. Our heuristics are able to find schedulable implementations under limited resources, achieving...... an efficient utilization of the system. The developed algorithms are evaluated using extensive experiments and a real-life example....

  17. Design Optimization of Multi-Cluster Embedded Systems for Real-Time Applications

    DEFF Research Database (Denmark)

    Pop, Paul; Eles, Petru; Peng, Zebo

    2006-01-01

    We present an approach to design optimization of multi-cluster embedded systems consisting of time-triggered and event-triggered clusters, interconnected via gateways. In this paper, we address design problems which are characteristic to multi-clusters: partitioning of the system functionality...... into time-triggered and event-triggered domains, process mapping, and the optimization of parameters corresponding to the communication protocol. We present several heuristics for solving these problems. Our heuristics are able to find schedulable implementations under limited resources, achieving...... an efficient utilization of the system. The developed algorithms are evaluated using extensive experiments and a real-life example....

  18. Ostomy-related problems and their impact on quality of life of colorectal cancer ostomates: a systematic review

    NARCIS (Netherlands)

    Sylvia M. Vonk-Klaassen; Hilde M. de Vocht; Erik Hans Eddes; Prof. Dr. Marieke J. Schuurmans; Marjolein E.M. den Ouden

    2016-01-01

    Aim Many long-term ostomates are ‘out-of-sight’ of healthcare, and it is unknown how ostomates deal with ostomy- related problems and how these problems affect their quality of life (QOL). The aim is to examine patient-related studies describing ostomy-related problems and their impact on the

  19. Ostomy-related problems and their impact on quality of life of colorectal cancer ostomates : a systematic review

    NARCIS (Netherlands)

    Vonk-Klaassen, Sylvia M.; de Vocht, Hilde M.; den Ouden, Marjolein E M; Eddes, Eric Hans; Schuurmans, Marieke J.

    2016-01-01

    Aim: Many long-term ostomates are ‘out-of-sight’ of healthcare, and it is unknown how ostomates deal with ostomy-related problems and how these problems affect their quality of life (QOL). The aim is to examine patient-related studies describing ostomy-related problems and their impact on the

  20. A Local Search Modeling for Constrained Optimum Paths Problems (Extended Abstract

    Directory of Open Access Journals (Sweden)

    Quang Dung Pham

    2009-10-01

    Full Text Available Constrained Optimum Path (COP problems appear in many real-life applications, especially on communication networks. Some of these problems have been considered and solved by specific techniques which are usually difficult to extend. In this paper, we introduce a novel local search modeling for solving some COPs by local search. The modeling features the compositionality, modularity, reuse and strengthens the benefits of Constrained-Based Local Search. We also apply the modeling to the edge-disjoint paths problem (EDP. We show that side constraints can easily be added in the model. Computational results show the significance of the approach.

  1. "Real-life" treatment of chronic pain: Targets and goals.

    Science.gov (United States)

    Ablin, Jacob N; Buskila, Dan

    2015-02-01

    Treating chronic pain is a complex challenge. While textbooks and medical education classically categorize pain as originating from peripheral (nociceptive), neuropathic, or centralized origins, in real life each and every patient may present a combination of various pain sources, types, and mechanisms. Moreover, individual patients may evolve and develop differing types of pain throughout their clinical follow-up, further emphasizing the necessity to maintain clinical diligence during the evaluation and follow-up of these patients. Rational treatment of patients suffering from chronic pain must attempt at deconstructing complex pain cases, identifying variegate pain generators, and targeting them with appropriate interventions, while incorporating both pharmacological and non-pharmacological strategies, rather than focusing on the total pain level, which represents an integral of all pain types. Failing to recognize the coexistence of different types of pain in an individual patient and escalating medications only on the basis of total pain intensity are liable to lead to both ineffective control of pain and increased untoward effects. In the current review, we outline strategies for deconstructing complex pain and therapeutic suggestions. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Estimation of Tri-Axial Walking Ground Reaction Forces of Left and Right Foot from Total Forces in Real-Life Environments

    Directory of Open Access Journals (Sweden)

    Erfan Shahabpoor

    2018-06-01

    Full Text Available Continuous monitoring of natural human gait in real-life environments is essential in many applications including disease monitoring, rehabilitation, and professional sports. Wearable inertial measurement units are successfully used to measure body kinematics in real-life environments and to estimate total walking ground reaction forces GRF(t using equations of motion. However, for inverse dynamics and clinical gait analysis, the GRF(t of each foot is required separately. Using an experimental dataset of 1243 tri-axial separate-foot GRF(t time histories measured by the authors across eight years, this study proposes the ‘Twin Polynomial Method’ (TPM to estimate the tri-axial left and right foot GRF(t signals from the total GRF(t signals. For each gait cycle, TPM fits polynomials of degree five, eight, and nine to the known single-support part of the left and right foot vertical, anterior-posterior, and medial-lateral GRF(t signals, respectively, to extrapolate the unknown double-support parts of the corresponding GRF(t signals. Validation of the proposed method both with force plate measurements (gold standard in the laboratory, and in real-life environment showed a peak-to-peak normalized root mean square error of less than 2.5%, 6.5% and 7.5% for the estimated GRF(t signals in the vertical, anterior-posterior and medial-lateral directions, respectively. These values show considerable improvement compared with the currently available GRF(t decomposition methods in the literature.

  3. Enhancement of problem solving ability of high school students through learning with real engagement in active problem solving (REAPS) model on the concept of heat transfer

    Science.gov (United States)

    Yulindar, A.; Setiawan, A.; Liliawati, W.

    2018-05-01

    This study aims to influence the enhancement of problem solving ability before and after learning using Real Engagement in Active Problem Solving (REAPS) model on the concept of heat transfer. The research method used is quantitative method with 35 high school students in Pontianak as sample. The result of problem solving ability of students is obtained through the test in the form of 3 description questions. The instrument has tested the validity by the expert judgment and field testing that obtained the validity value of 0.84. Based on data analysis, the value of N-Gain is 0.43 and the enhancement of students’ problem solving ability is in medium category. This was caused of students who are less accurate in calculating the results of answers and they also have limited time in doing the questions given.

  4. Mild cognitive impairment in early life and mental health problems in adulthood.

    Science.gov (United States)

    Chen, Chuan-Yu; Lawlor, John P; Duggan, Anne K; Hardy, Janet B; Eaton, William W

    2006-10-01

    We assessed the extent to which borderline mental retardation and mental retardation at preschool ages are related to emotional and behavioral problems in young adulthood. We also explored early risk factors for having mental health problems as a young adult that might be related to preschool differences in cognitive ability. We used data from a cohort of births studied in the Johns Hopkins Collaborative Perinatal Study and followed up in the Pathways to Adulthood Study. Preschool cognitive functioning was assessed at 4 years of age. Individual characteristics, psychosocial factors, and mental problems were prospectively evaluated from birth through young adulthood. Children with subaverage cognitive abilities were more likely to develop mental health problems than their counterparts with IQs above 80. Inadequate family interactions were shown to increase 2- to 4-fold the risk of emotional or behavioral problems among children with borderline mental retardation. Subaverage cognitive functioning in early life increases later risk of mental health problems. Future research may help to delineate possible impediments faced at different developmental stages and guide changes in supportive services to better address the needs of children with borderline mental retardation.

  5. Authentic Education by Providing a Situation for Student-Selected Problem-Based Learning

    Science.gov (United States)

    Strimel, Greg

    2014-01-01

    Students are seldom given an authentic experience within school that allows them the opportunity to solve real-life complex engineering design problems that have meaning to their lives and/ or the greater society. They are often confined to learning environments that are limited by the restrictions set by course content for assessment purposes and…

  6. Living with psoriasis: prevalence of shame, anger, worry, and problems in daily activities and social life.

    Science.gov (United States)

    Sampogna, Francesca; Tabolli, Stefano; Abeni, Damiano

    2012-05-01

    Psychosocial problems are frequent among patients with psoriasis. The aim of this study was to analyse the prevalence of some specific psychosocial issues. These were evaluated in 936 patients using the emotions and functioning scales of the Skindex-29 questionnaire. The problems most frequently experienced were: shame, anger, worry, difficulties in daily activities and social life. All problems were associated with the severity of psoriasis and with depression or anxiety. Shame, worry and annoyance were more frequent in women than in men, and shame and anger were associated with a low level of education. Impairment in work/hobbies was significantly higher in patients with palmoplantar psoriasis and those with arthro-pathic psoriasis. In conclusion, clinicians could gain important insights about their patients by looking at the single items of a quality of life instrument, to identify patients with high levels of emotional and social problems, in order to improve quality of care.

  7. An introduction to real analysis

    CERN Document Server

    Ball, Derek G

    1973-01-01

    An Introduction to Real Analysis presents the concepts of real analysis and highlights the problems which necessitate the introduction of these concepts. Topics range from sets, relations, and functions to numbers, sequences, series, derivatives, and the Riemann integral. This volume begins with an introduction to some of the problems which are met in the use of numbers for measuring, and which provide motivation for the creation of real analysis. Attention then turns to real numbers that are built up from natural numbers, with emphasis on integers, rationals, and irrationals. The chapters tha

  8. Perceived motor problems in daily life: Focus group interviews with people with Noonan syndrome and their relatives.

    Science.gov (United States)

    Croonen, Ellen A; Harmsen, Mirjam; Van der Burgt, Ineke; Draaisma, Jos M; Noordam, Kees; Essink, Marlou; Nijhuis-van der Sanden, Maria W G

    2016-09-01

    Studies from a patient perspective on motor performance problems in Noonan syndrome in daily life are lacking. The aims of this study were to provide insight into the motor performance problems that people with Noonan syndrome and/or their relatives experienced, the major consequences they suffered, the benefits of interventions they experienced, and the experiences with healthcare professionals they mentioned. We interviewed 10 adults with Noonan syndrome (two were joined by their parent), and 23 mothers (five of whom had Noonan syndrome), nine fathers (one of whom had Noonan syndrome) and one cousin who reported on 28 children with Noonan syndrome. People with Noonan syndrome reported particular problems related to pain, decreased muscle strength, fatigue, and clumsiness, which had an evident impact on functioning in daily life. Most participants believed that problems with motor performance improved with exercise, appropriate physiotherapy guidance, and other supportive interventions. Nevertheless, people with Noonan syndrome and/or their relatives did not feel heard and supported and experienced no understanding of their problems by healthcare professionals. This was the first study from a patient perspective that described the motor performance problems in people with Noonan syndrome, the major consequences in daily life, the positive experiences of interventions and the miscommunication with healthcare professionals. To achieve optimal support, healthcare professionals, as well as people with Noonan syndrome and/or their relatives themselves, should be aware of these frequently presented problems with motor performance. Research on these different aspects is needed to better understand and support people with Noonan syndrome.© 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  9. Junior High School Students’ Perception about Simple Environmental Problem as an Impact of Problem based Learning

    Science.gov (United States)

    Tapilouw, M. C.; Firman, H.; Redjeki, S.; Chandra, D. T.

    2017-09-01

    Environmental problem is a real problem that occur in student’s daily life. Junior high school students’ perception about environmental problem is interesting to be investigated. The major aim of this study is to explore junior high school students’ perception about environmental problems around them and ways to solve the problem. The subject of this study is 69 Junior High School Students from two Junior High School in Bandung. This study use two open ended question. The core of first question is environmental problem around them (near school or house). The core of second question is the way to prevent or to solve the problem. These two question are as an impact of problem based learning in science learning. There are two major findings in this study. The first finding, based on most students’ perception, plastic waste cause an environmental problem. The second finding, environmental awareness can be a solution to prevent environmental pollution. The third finding, most student can classify environmental pollution into land, water and air pollution. We can conclude that Junior High School Students see the environmental problem as a phenomenon and teacher can explore environmental problem to guide the way of preventing and resolving environmental problem.

  10. Linking the microscopic view of chemistry to real-life experiences: Intertextuality in a high-school science classroom

    Science.gov (United States)

    Wu, Hsin-Kai

    2003-11-01

    Chemistry learning involves establishing conceptual relationships among macroscopic, microscopic, and symbolic representations. Employing the notion of intertextuality to conceptualize these relationships, this study investigates how class members interactionally construct meanings of chemical representations by connecting them to real-life experiences and how the teachers' content knowledge shapes their ways to coconstruct intertextual links with students. Multiple sources of data were collected over 7 weeks with a participation of 25 eleventh graders, an experienced teacher, and a student teacher. An examination of classroom discourse shows that the intertextual links between the microscopic view of chemistry and students' real-life experiences could be initiated by students and instigated by the teachers. The teachers applied several discursive strategies to scaffold students building meaningful links based on their prior knowledge and experiences. Additionally, the experienced teacher with stronger content knowledge tended to present links in both dialogic and monologic discourses. Yet, the relatively limited content knowledge did not necessarily constrain the student teacher's interactions with students. The findings of this study provide a backdrop for further research to explore how chemistry is learned and taught in a class through the social constructivist lens.

  11. Recent trends in robot-assisted therapy environments to improve real-life functional performance after stroke.

    Science.gov (United States)

    Johnson, Michelle J

    2006-12-18

    Upper and lower limb robotic tools for neuro-rehabilitation are effective in reducing motor impairment but they are limited in their ability to improve real world function. There is a need to improve functional outcomes after robot-assisted therapy. Improvements in the effectiveness of these environments may be achieved by incorporating into their design and control strategies important elements key to inducing motor learning and cerebral plasticity such as mass-practice, feedback, task-engagement, and complex problem solving. This special issue presents nine articles. Novel strategies covered in this issue encourage more natural movements through the use of virtual reality and real objects and faster motor learning through the use of error feedback to guide acquisition of natural movements that are salient to real activities. In addition, several articles describe novel systems and techniques that use of custom and commercial games combined with new low-cost robot systems and a humanoid robot to embody the " supervisory presence" of the therapy as possible solutions to exercise compliance in under-supervised environments such as the home.

  12. Recent trends in robot-assisted therapy environments to improve real-life functional performance after stroke

    Directory of Open Access Journals (Sweden)

    Johnson Michelle J

    2006-12-01

    Full Text Available Abstract Upper and lower limb robotic tools for neuro-rehabilitation are effective in reducing motor impairment but they are limited in their ability to improve real world function. There is a need to improve functional outcomes after robot-assisted therapy. Improvements in the effectiveness of these environments may be achieved by incorporating into their design and control strategies important elements key to inducing motor learning and cerebral plasticity such as mass-practice, feedback, task-engagement, and complex problem solving. This special issue presents nine articles. Novel strategies covered in this issue encourage more natural movements through the use of virtual reality and real objects and faster motor learning through the use of error feedback to guide acquisition of natural movements that are salient to real activities. In addition, several articles describe novel systems and techniques that use of custom and commercial games combined with new low-cost robot systems and a humanoid robot to embody the " supervisory presence" of the therapy as possible solutions to exercise compliance in under-supervised environments such as the home.

  13. Viable Solutions for seemingly Intractable Problems

    Directory of Open Access Journals (Sweden)

    Ashok Natarajan

    2015-10-01

    Full Text Available Life is filled with seemingly intractable problems. But life wisdom affirms that if there is a problem, there must be a solution. Or better yet, the solution to the problem lies within the problem itself. Problems have their roots in disharmony. Disharmony arises when a part separates itself from the whole and acts independently of the wider reality of which it is a part, as financial markets have separated themselves from the real economy and economy has detached itself from social and ecological consequences. Insistence on out-moded approaches under new conditions generates intractable problems, as when the framework of a heterogeneous nation-state is employed for the dominance of a single ethnic or religious group. Knowledge and culture are the supreme values of a society and core element of its capacity for accomplishment and development, yet both tend to be exclusively possessed by elites for their own benefit, rather than freely distributed to maximize their impact on society as a whole. Society evolves by the transformation of ignorance into knowledge. Life evolves by organization. The linking and integration of social organizations spur development. Mind itself is an organization and powerful force for development. Energy makes organization more efficient. Any problem can be solved by raising the effectiveness of energy by converting it into skill or capacity and transforming it into power through organization. What one person sees as a problem is an opportunity for another with wider vision. The difference in perception accounts for the difference in levels of accomplishment. So, those with the right perspective see opportunities where others see insolvable problems. Current problems are the result of irrationality, refusal to benefit from past experience and insistence on repeating past errors. Modern science, which was born to fight the superstition of religion, has become a source of superstition. Fully availing of the latest

  14. Rationale and design of the PREDICE project: cost-effectiveness of type 2 diabetes prevention among high-risk Spanish individuals following lifestyle intervention in real-life primary care setting.

    Science.gov (United States)

    Costa, Bernardo; Cabré, Joan J; Sagarra, Ramon; Solà-Morales, Oriol; Barrio, Francisco; Piñol, Josep L; Cos, Xavier; Bolíbar, Bonaventura; Castell, Conxa; Kissimova-Skarbek, Katarzyna; Tuomilehto, Jaakko

    2011-08-04

    Type 2 diabetes is an important preventable disease and a growing public health problem. Based on information provided by clinical trials, we know that Type 2 diabetes can be prevented or delayed by lifestyle intervention. In view of translating the findings of diabetes prevention research into real-life it is necessary to carry out community-based evaluations so as to learn about the feasibility and effectiveness of locally designed and implemented programmes. The aim of this project was to assess the effectiveness of an active real-life primary care strategy in high-risk individuals for developing diabetes, and then evaluate its efficiency. Cost-Effectiveness analysis of the DE-PLAN (Diabetes in Europe - Prevention using Lifestyle, physical Activity and Nutritional intervention) project when applied to a Mediterranean population in Catalonia (DE-PLAN-CAT). Multicenter, longitudinal cohort assessment (4 years) conducted in 18 primary health-care centres (Catalan Health Institute). Individuals without diabetes aged 45-75 years were screened using the Finnish Diabetes Risk Score - FINDRISC - questionnaire and a 2-h oral glucose tolerance test. All high risk tested individuals were invited to participate in either a usual care intervention (information on diet and cardiovascular health without individualized programme), or the intensive DE-PLAN educational program (individualized or group) periodically reinforced. Oral glucose tolerance test was repeated yearly to determine diabetes incidence. Besides measuring the accumulated incidence of diabetes, information was collected on economic impact of the interventions in both cohorts (using direct and indirect cost questionnaires) and information on utility measures (Quality Adjusted Life Years). A cost-utility and a cost-effectiveness analysis will be performed and data will be modelled to predict long-term cost-effectiveness. The project was intended to evidence that a substantial reduction in Type 2 diabetes incidence

  15. Real/Life: New British Art and the Reception of Contemporary British Art in Japan

    Directory of Open Access Journals (Sweden)

    Kajiya Kenji

    2016-07-01

    Full Text Available This essay explores the ways in which the exhibition Real/Life: New British Art was conceived and received in Japan, where contemporary British art has been shown since the 1960s. Taking place at five museums in the country between 1998 and 1999, the exhibition aimed to showhow British artists in the 1990s struggled with realities, internal and external, but its response was not as satisfactory as was expected. The essay examines the exhibition as a turning point for the transformation of exhibition culture in Japan from nationally themed exhibitions to showcases of contemporary art in the global context.

  16. Sexual functioning, beliefs about sexual functioning and quality of life of women with infertility problems

    Directory of Open Access Journals (Sweden)

    Prathibha Agustus

    2017-01-01

    Full Text Available Background: The study was conducted in the background of paucity of studies examining the sexual and psychosocial functioning of women with infertility. Aims: The study explored sexual functioning in women with infertility problems, their beliefs about sexuality and their quality of life. Settings and Design: A single group exploratory design with non-probability purposive sampling was used. A total of 30 participants diagnosed with primary infertility were included in the study. Materials and Methods: The data were obtained by individual administration of the following tools: Semi-structured interview schedule, Female Sexual Functioning Inventory, Sexual Dysfunctional Beliefs Questionnaire, World Health Organization Quality of Life Scale − BREF Version and General Health Questionnaire-12. The data obtained were analyzed using descriptive statistics and non-parametric tests. Results: About half of the participants had sexual dysfunction. Pain-related problems were most commonly reported (50%. Factors contributing to dysfunction included inadequate knowledge about sex, sexual stimulation and sexual communication. Along with inadequate self-image, negative childhood experiences, financial difficulties and marital discord in parents influenced the perception of self. Majority of the women had dysfunctional beliefs about sexuality (56%, and greater beliefs were found to be in the domain of sexual conservatism. The overall quality of life was poor, and 56% of women experienced psychological distress. There was significant positive correlation between sexual conservatism and experience of pain and overall sexual functioning. Conclusion: Women with infertility bear dysfunctional beliefs and suffer from problems in sexual functioning, have low quality of life and high psychological distress.

  17. Problem-Based Learning in the Earth and Space Science Classroom, K-12

    Science.gov (United States)

    McConnell, Tom J.; Parker, Joyce; Eberhardt, Janet

    2017-01-01

    If you've ever asked yourself whether problem-based learning (PBL) can bring new life to both your teaching and your students' learning, here's your answer: Yes. This all-in-one guide will help you engage your students in scenarios that represent real-world science in all its messy, thought-provoking glory. The scenarios will prompt K-12 students…

  18. The fragrance hand immersion study - an experimental model simulating real-life exposure for allergic contact dermatitis on the hands

    DEFF Research Database (Denmark)

    Heydorn, S; Menné, T; Andersen, K E

    2003-01-01

    .p.m.), whilst during the following 2 weeks, the concentration was relatively high (approximately 250 p.p.m.), imitating real-life exposure to a household product like dishwashing liquid diluted in water and the undiluted product, respectively. Evaluation was made using a clinical scale and laser Doppler flow...

  19. Real-life compliance and persistence among users of subcutaneous and sublingual allergen immunotherapy.

    Science.gov (United States)

    Kiel, Menno A; Röder, Esther; Gerth van Wijk, Roy; Al, Maiwenn J; Hop, Wim C J; Rutten-van Mölken, Maureen P M H

    2013-08-01

    Subcutaneous allergen immunotherapy (SCIT) and sublingual allergen immunotherapy (SLIT) are safe and effective treatments of allergic rhinitis, but high levels of compliance and persistence are crucial to achieving the desired clinical effects. Our objective was to assess levels and predictors of compliance and persistence among grass pollen, tree pollen, and house dust mite immunotherapy users in real life and to estimate the costs of premature discontinuation. We performed a retrospective analysis of a community pharmacy database from The Netherlands containing data from 6486 patients starting immunotherapy for 1 or more of the allergens of interest between 1994 and 2009. Two thousand seven hundred ninety-six patients received SCIT, and 3690 received SLIT. Time to treatment discontinuation was analyzed and included Cox proportional hazard models with time-dependent covariates, where appropriate. Overall, only 18% of users reached the minimally required duration of treatment of 3 years (SCIT, 23%; SLIT, 7%). Median durations for SCIT and SLIT users were 1.7 and 0.6 years, respectively (P < .001). Other independent predictors of premature discontinuation were prescriber, with patients of general practitioners demonstrating longer persistence than those of allergologists and other medical specialists; single-allergen immunotherapy, lower socioeconomic status; and younger age. Of the persistent patients, 56% were never late in picking up their medication from the pharmacy. Direct medication costs per nonpersistent patient discontinuing in the third year of treatment were €3800, an amount that was largely misspent. Real-life persistence is better in SCIT users than in SLIT users, although it is low overall. There is an urgent need for further identification of potential barriers and measures that will enhance persistence and compliance. Copyright © 2013 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

  20. A granular t abu search algorithm for a real case study of a vehicle routing problem with a heterogeneous fleet and time windows

    Energy Technology Data Exchange (ETDEWEB)

    Bernal, Jose; Escobar, John Willmer; Linfati, Rodrigo

    2017-07-01

    We consider a real case study of a vehicle routing problem with a heterogeneous fleet and time windows (HFVRPTW) for a franchise company bottling Coca-Cola products in Colombia. This study aims to determine the routes to be performed to fulfill the demand of the customers by using a heterogeneous fleet and considering soft time windows. The objective is to minimize the distance traveled by the performed routes. Design/methodology/approach: We propose a two-phase heuristic algorithm. In the proposed approach, after an initial phase (first phase), a granular tabu search is applied during the improvement phase (second phase). Two additional procedures are considered to help that the algorithm could escape from local optimum, given that during a given number of iterations there has been no improvement. Findings: Computational experiments on real instances show that the proposed algorithm is able to obtain high-quality solutions within a short computing time compared to the results found by the software that the company currently uses to plan the daily routes. Originality/value: We propose a novel metaheuristic algorithm for solving a real routing problem by considering heterogeneous fleet and time windows. The efficiency of the proposed approach has been tested on real instances, and the computational experiments shown its applicability and performance for solving NP-Hard Problems related with routing problems with similar characteristics. The proposed algorithm was able to improve some of the current solutions applied by the company by reducing the route length and the number of vehicles.

  1. A granular t abu search algorithm for a real case study of a vehicle routing problem with a heterogeneous fleet and time windows

    International Nuclear Information System (INIS)

    Bernal, Jose; Escobar, John Willmer; Linfati, Rodrigo

    2017-01-01

    We consider a real case study of a vehicle routing problem with a heterogeneous fleet and time windows (HFVRPTW) for a franchise company bottling Coca-Cola products in Colombia. This study aims to determine the routes to be performed to fulfill the demand of the customers by using a heterogeneous fleet and considering soft time windows. The objective is to minimize the distance traveled by the performed routes. Design/methodology/approach: We propose a two-phase heuristic algorithm. In the proposed approach, after an initial phase (first phase), a granular tabu search is applied during the improvement phase (second phase). Two additional procedures are considered to help that the algorithm could escape from local optimum, given that during a given number of iterations there has been no improvement. Findings: Computational experiments on real instances show that the proposed algorithm is able to obtain high-quality solutions within a short computing time compared to the results found by the software that the company currently uses to plan the daily routes. Originality/value: We propose a novel metaheuristic algorithm for solving a real routing problem by considering heterogeneous fleet and time windows. The efficiency of the proposed approach has been tested on real instances, and the computational experiments shown its applicability and performance for solving NP-Hard Problems related with routing problems with similar characteristics. The proposed algorithm was able to improve some of the current solutions applied by the company by reducing the route length and the number of vehicles.

  2. Learning mechanisms in multidisciplinary teamwork with real customers and open-ended problems

    Science.gov (United States)

    Heikkinen, Juho; Isomöttönen, Ville

    2015-11-01

    Recently, there has been a trend towards adding a multidisciplinary or multicultural element to traditional monodisciplinary project courses in computing and engineering. In this article, we examine the implications of multidisciplinarity for students' learning experiences during a one-semester project course for real customers. We use a qualitative research approach and base our analysis on students' learning reports on three instances of a project course titled Multidisciplinary working life project. The main contribution of this article is the unified theoretical picture of the learning mechanisms stemming from multidisciplinarity. Our main conclusions are that (1) students generally have a positive view of multidisciplinarity; (2) multidisciplinary teams enable students to better identify their own expertise, which leads to increased occupational identity; and (3) learning experiences are not fixed, as team spirit and student attitude play an important role in how students react to challenging situations arising from introduction of the multidisciplinarity.

  3. BRAIN Journal - Solving Optimization Problems via Vortex Optimization Algorithm and Cognitive Development Optimization Algorithm

    OpenAIRE

    Ahmet Demir; Utku Kose

    2016-01-01

    ABSTRACT In the fields which require finding the most appropriate value, optimization became a vital approach to employ effective solutions. With the use of optimization techniques, many different fields in the modern life have found solutions to their real-world based problems. In this context, classical optimization techniques have had an important popularity. But after a while, more advanced optimization problems required the use of more effective techniques. At this point, Computer Sc...

  4. An application of robust ridge regression model in the presence of outliers to real data problem

    Science.gov (United States)

    Shariff, N. S. Md.; Ferdaos, N. A.

    2017-09-01

    Multicollinearity and outliers are often leads to inconsistent and unreliable parameter estimates in regression analysis. The well-known procedure that is robust to multicollinearity problem is the ridge regression method. This method however is believed are affected by the presence of outlier. The combination of GM-estimation and ridge parameter that is robust towards both problems is on interest in this study. As such, both techniques are employed to investigate the relationship between stock market price and macroeconomic variables in Malaysia due to curiosity of involving the multicollinearity and outlier problem in the data set. There are four macroeconomic factors selected for this study which are Consumer Price Index (CPI), Gross Domestic Product (GDP), Base Lending Rate (BLR) and Money Supply (M1). The results demonstrate that the proposed procedure is able to produce reliable results towards the presence of multicollinearity and outliers in the real data.

  5. Natalizumab treatment reduces fatigue in multiple sclerosis. Results from the TYNERGY trial; a study in the real life setting

    DEFF Research Database (Denmark)

    Svenningsson, Anders; Falk, Eva; Celius, Elisabeth G

    2013-01-01

    . The TYNERGY study aimed to further evaluate the effects of natalizumab treatment on MS-related fatigue. In this one-armed clinical trial including 195 MS patients, natalizumab was prescribed in a real-life setting, and a validated questionnaire, the Fatigue Scale for Motor and Cognitive functions (FSMC......), was used both before and after 12 months of treatment to evaluate a possible change in the fatigue experienced by the patients. In the treated cohort all measured variables, that is, fatigue score, quality of life, sleepiness, depression, cognition, and disability progression were improved from baseline...

  6. A lower bound for the node, edge, and arc routing problem

    DEFF Research Database (Denmark)

    Bach, Lukas; Hasle, Geir; Wøhlk, Sanne

    2013-01-01

    The Node, Edge, and Arc Routing Problem (NEARP) was defined by Prins and Bouchenoua in 2004, although similar problems have been studied before. This problem, also called the Mixed Capacitated General Routing Problem (MCGRP), generalizes the classical Capacitated Vehicle Routing Problem (CVRP......), the Capacitated Arc Routing Problem (CARP), and the General Routing Problem. It captures important aspects of real-life routing problems that were not adequately modeled in previous Vehicle Routing Problem (VRP) variants. The authors also proposed a memetic algorithm procedure and defined a set of test instances...... called the CBMix benchmark. The NEARP definition and investigation contribute to the development of rich VRPs. In this paper we present the first lower bound procedure for the NEARP. It is a further development of lower bounds for the CARP. We also define two novel sets of test instances to complement...

  7. Real-time video analysis for retail stores

    Science.gov (United States)

    Hassan, Ehtesham; Maurya, Avinash K.

    2015-03-01

    With the advancement in video processing technologies, we can capture subtle human responses in a retail store environment which play decisive role in the store management. In this paper, we present a novel surveillance video based analytic system for retail stores targeting localized and global traffic estimate. Development of an intelligent system for human traffic estimation in real-life poses a challenging problem because of the variation and noise involved. In this direction, we begin with a novel human tracking system by an intelligent combination of motion based and image level object detection. We demonstrate the initial evaluation of this approach on available standard dataset yielding promising result. Exact traffic estimate in a retail store require correct separation of customers from service providers. We present a role based human classification framework using Gaussian mixture model for this task. A novel feature descriptor named graded colour histogram is defined for object representation. Using, our role based human classification and tracking system, we have defined a novel computationally efficient framework for two types of analytics generation i.e., region specific people count and dwell-time estimation. This system has been extensively evaluated and tested on four hours of real-life video captured from a retail store.

  8. Blue Tigers, Black Tapirs, & the Pied Raven of the Faroe Islands: Teaching Genetic Drift Using Real-Life Animal Examples

    Science.gov (United States)

    Robischon, Marcel

    2015-01-01

    Genetic drift is a concept of population genetics that is central to understanding evolutionary processes and aspects of conservation biology. It is frequently taught using rather abstract representations. I introduce three real-life zoological examples, based on historical and recent color morphs of tigers, tapirs, and ravens, that can complement…

  9. Economic Stress, Emotional Quality of Life, and Problem Behavior in Chinese Adolescents with and without Economic Disadvantage

    Science.gov (United States)

    Shek, Daniel T. L.

    2005-01-01

    The relationships between perceived economic stress (current economic hardship and future economic worry) and emotional quality of life (existential well-being, life satisfaction, self-esteem, sense of mastery, psychological morbidity) as well as problem behavior (substance abuse and delinquency) were examined in 1519 Chinese adolescents with and…

  10. Bringing Curriculum to Life. Enacting Project-Based Learning in Music Programs

    Science.gov (United States)

    Tobias, Evan S.; Campbell, Mark Robin; Greco, Phillip

    2015-01-01

    At its core, project-based learning is based on the idea that real-life problems capture student interest, provoke critical thinking, and develop skills as they engage in and complete complex undertakings that typically result in a realistic product, event, or presentation to an audience. This article offers a starting point for music teachers who…

  11. A novel heuristic algorithm for capacitated vehicle routing problem

    Science.gov (United States)

    Kır, Sena; Yazgan, Harun Reşit; Tüncel, Emre

    2017-09-01

    The vehicle routing problem with the capacity constraints was considered in this paper. It is quite difficult to achieve an optimal solution with traditional optimization methods by reason of the high computational complexity for large-scale problems. Consequently, new heuristic or metaheuristic approaches have been developed to solve this problem. In this paper, we constructed a new heuristic algorithm based on the tabu search and adaptive large neighborhood search (ALNS) with several specifically designed operators and features to solve the capacitated vehicle routing problem (CVRP). The effectiveness of the proposed algorithm was illustrated on the benchmark problems. The algorithm provides a better performance on large-scaled instances and gained advantage in terms of CPU time. In addition, we solved a real-life CVRP using the proposed algorithm and found the encouraging results by comparison with the current situation that the company is in.

  12. Measuring life by real people

    DEFF Research Database (Denmark)

    Hansen, Ellen Kathrine

    2010-01-01

    This article describes how information about Active House is obtained through tests done on demonstration buildings. Tests in which life in intelligent and energy-optimised homes takes centre stage, and where ratings are obtained via human behaviour and wellbeing. The article also describes exper...

  13. The Status and Problems of Women in Working Life in Turkey

    Directory of Open Access Journals (Sweden)

    Hulya Gul

    2014-04-01

    Full Text Available The situation of woman in working life is a multidimensional public health issue and should be investigated related with many factors such as economic, social, biological, cultural factors. Women have been working in each step of production through history, but are still evaluated as a disadvantaged group. Nowadays, many new legal arrangements for regulating the working life have been made in Turkey. The participation of women to the labor force is accepted to be an important element of sustainable progress, social development and prosperity of the community, however, women participation ratios in the manpower in Turkey are not yet at desired level. Attentively, evaluation of the problems women encounter in working life indicates that occupational discrimination due to gender inequality is one of the leading problems. The working environment consists of many physical, chemical, biological and psychological factors known to be harmful to the general and reproductive health of women. Recognizing of these factors, which affect the health, is important for developing programs and policies intending to prevent them. Improvement of the working conditions of women and enhancing the employment opportunities are the most important steps for the economic and social prosperity of a country. A woman working happily in good conditions and earning her own money contributes the family budget, also spends most of her income and her spare time on her children, so that it will contribute to more healthy and educated generations. In order to improve of working conditions for women, all the rules and laws should be applied totally, and all concerned sides should carry out their responsibilities completely. Firstly, the working conditions should be offered to women with the least discomfort. Also, they should be supported with continuous occupational education, opportunities for their awareness and self-development should be created. [TAF Prev Med Bull 2014; 13

  14. Dried blood spots, valid screening for viral hepatitis and human immunodeficiency virus in real-life

    DEFF Research Database (Denmark)

    Mössner, Belinda K; Staugaard, Benjamin; Jensen, Janne

    2016-01-01

    AIM: To detect chronic hepatitis B (CHB), chronic hepatitis C (CHC) and human immunodeficiency virus (HIV) infections in dried blood spot (DBS) and compare these samples to venous blood sampling in real-life. METHODS: We included prospective patients with known viral infections from drug treatment......, but correctly classified 95% of the anti-HCV-positive patients with chronic and past infections. Anti-HBc and anti-HBS showed low sensitivity in DBS (68% and 42%). CONCLUSION: DBS sampling, combined with an automated analysis system, is a feasible screening method to diagnose chronic viral hepatitis and HIV...

  15. Peer Victimization among Classmates-Associations with Students' Internalizing Problems, Self-Esteem, and Life Satisfaction.

    Science.gov (United States)

    Låftman, Sara B; Modin, Bitte

    2017-10-13

    Bullying is a major problem in schools and a large number of studies have demonstrated that victims have a high excess risk of poor mental health. It may however also affect those who are not directly victimized by peers. The present study investigates whether peer victimization among classmates is linked to internalizing problems, self-esteem, and life satisfaction at the individual level, when the student's own victimization has been taken into account. The data were derived from the first wave of the Swedish part of Youth in Europe Study (YES!), including information on 4319 students in grade 8 (14-15 years of age) distributed across 242 classes. Results from multilevel analyses show a significant association between classes with a high proportion of students being victimized and higher levels of internalizing problems, lower self-esteem, and lower life satisfaction at the student level. This association holds when the student's own victimization has been taken into account. This suggests that peer victimization negatively affects those who are directly exposed, as well as their classmates. We conclude that efficient methods and interventions to reduce bullying in school are likely to benefit not only those who are victimized, but all students.

  16. SAROTA: application of specific absorption rate (SAR) and over-the-air (OTA) data for the characterization of the real-life exposure due to mobile phones

    International Nuclear Information System (INIS)

    Monebhurrun, Vikass

    2013-01-01

    The RF exposure level of a mobile phone is quantified by the measurement of the specific absorption rate (SAR) under laboratory conditions. The SAR which is measured while the mobile phone is operated at maximum power level does not reflect the real-life exposure scenario since the mobile phone typically re-adjusts its power level and frequency depending on the quality of the communication link with the nearest base station. The choice of a low RF exposure device based on the comparison of the relative SAR values of mobile phones can be misleading. The real-life RF exposure also depends on the over-the-air (OTA) performance of the mobile phone. Taken independently, the two sets of data do not allow a straightforward comparison of the global RF performance amongst mobile phones. A unique and simple parameter denoted as the SAROTA index is proposed for the characterization of mobile phones with regard to both RF exposure and OTA performance. The SAROTA index provides the real-life exposure index of the mobile phone.

  17. Son, you’re smoking on Facebook! College students’ disclosures on social networking sites as indicators of real-life risk behaviors

    NARCIS (Netherlands)

    van Hoof, Joris Jasper; Bekkers, Jeroen; van Vuuren, Hubrecht A.

    2014-01-01

    Health risk behavior in student populations is an issue of major concern, and students’ risk levels are difficult to determine. In this study, we explore the extent to which information disclosed publicly on Facebook provides reliable indications of five real-life health behaviors. Questionnaire

  18. Partially specified physics problems: university students' attitudes and performance

    International Nuclear Information System (INIS)

    Marusic, M; Erceg, N; Slisko, J

    2011-01-01

    In this research we asked the fourth year students (N = 50) of a technical faculty of the University of Split (Republic of Croatia) to solve a partially specified physics problem related to gravitational force. The task for the students was to decide whether the situation described in the problem is feasible or not. Nevertheless, the formulation of the problem is such that it does not give students any explicit advice regarding what to calculate or how to judge the feasibility of the given situation in the real world. The research was carried out using a structured written exam method. The worksheet was structured in order to assess explicitly a few elements of the students' problem-solving performance. Based on their results, the examinees were classified into four categories, depending on what they could or could not accomplish during problem solving. A majority of students were not able to solve the given physical problem completely. A selection of students' and professors' observations is also included. Our results show that traditionally formulated numerical exercises, which are mostly used in physics teaching, do not develop students' abilities in higher-order thinking (i.e. planning, decision making or result evaluation) to a desirable extent. We suggest that partially specified problems should be given to students, both in problem-solving sessions and exams, in order to prepare them for dealing with ill-structured tasks in real life.

  19. On real structures on rigid surfaces

    International Nuclear Information System (INIS)

    Kulikov, Vik S; Kharlamov, V M

    2002-01-01

    We construct examples of rigid surfaces (that is, surfaces whose deformation class consists of a unique surface) with a particular behaviour with respect to real structures. In one example the surface has no real structure. In another it has a unique real structure, which is not maximal with respect to the Smith-Thom inequality. These examples give negative answers to the following problems: the existence of real surfaces in each deformation class of complex surfaces, and the existence of maximal real surfaces in every complex deformation class that contains real surfaces. Moreover, we prove that there are no real surfaces among surfaces of general type with p g =q=0 and K 2 =9. These surfaces also provide new counterexamples to the 'Dif = Def' problem

  20. Problem solving performance and learning strategies of undergraduate students who solved microbiology problems using IMMEX educational software

    Science.gov (United States)

    Ebomoyi, Josephine Itota

    The objectives of this study were as follows: (1) Determine the relationship between learning strategies and performance in problem solving, (2) Explore the role of a student's declared major on performance in problem solving, (3) Understand the decision making process of high and low achievers during problem solving. Participants (N = 65) solved problems using the Interactive multimedia exercise (IMMEX) software. All participants not only solved "Microquest," which focuses on cellular processes and mode of action of antibiotics, but also "Creeping Crud," which focuses on the cause, origin and transmission of diseases. Participants also responded to the "Motivated Strategy Learning Questionnaire" (MSLQ). Hierarchical multiple regression was used for analysis with GPA (Gracie point average) as a control. There were 49 (78.6%) that successfully solved "Microquest" while 52 (82.5%) successfully solved "Creeping Crud". Metacognitive self regulation strategy was significantly (p low achievers. Common strategies and attributes included metacognitive skills, writing to keep track, using prior knowledge. Others included elements of frustration/confusion and self-esteem problems. The implications for educational and relevance to real life situations are discussed.

  1. Improving Group Work Practices in Teaching Life Sciences: Trialogical Learning

    Science.gov (United States)

    Tammeorg, Priit; Mykkänen, Anna; Rantamäki, Tomi; Lakkala, Minna; Muukkonen, Hanni

    2017-08-01

    Trialogical learning, a collaborative and iterative knowledge creation process using real-life artefacts or problems, familiarizes students with working life environments and aims to teach skills required in the professional world. We target one of the major limitation factors for optimal trialogical learning in university settings, inefficient group work. We propose a course design combining effective group working practices with trialogical learning principles in life sciences. We assess the usability of our design in (a) a case study on crop science education and (b) a questionnaire for university teachers in life science fields. Our approach was considered useful and supportive of the learning process by all the participants in the case study: the students, the stakeholders and the facilitator. Correspondingly, a group of university teachers expressed that the trialogical approach and the involvement of stakeholders could promote efficient learning. In our case in life sciences, we identified the key issues in facilitating effective group work to be the design of meaningful tasks and the allowance of sufficient time to take action based on formative feedback. Even though trialogical courses can be time consuming, the experience of applying knowledge in real-life cases justifies using the approach, particularly for students just about to enter their professional careers.

  2. An Analyses and Solution Proposals Toward Social Gender Equality Problems in Business Life at Work Place in Turkey

    Directory of Open Access Journals (Sweden)

    Ayse Kocabacak

    2015-11-01

    Full Text Available Gender inequality is a problem in the World as well as in Turkey. What is referred by this problem here is the gender discrimination and thus inequality and injustice in opportunities that women face in a society. It appears in different forms in business life or at work place (inequalities in employment, wages, social benefits and education as well as obstacles in career rise, easy dismissal or layoff, sexual harassment / persecution / mobbing, etc.. In this study, this problem is investigated and evaluated in terms of gender equality issues that women face in Turkey especially in business life. For this purpose, current situation analysis and findings in Turkey from past to present have been made, statistical comparisons have been given against global averages, in which areas of business life it appears the most and from what reasons it originates, reason for its persistence and improvement over time has been researched, and based on our findings, recommendations for possible solutions have been presented.

  3. Can the response to Omalizumab be influenced by treatment duration? A real-life study.

    Science.gov (United States)

    Sposato, Bruno; Scalese, Marco; Latorre, Manuela; Novelli, Federica; Scichilone, Nicola; Milanese, Manlio; Olivieri, Carmela; Perrella, Antonio; Paggiaro, Pierluigi

    2017-06-01

    It is unknown whether Omalizumab effectiveness changes over the course of time. Our retrospective real-life study tried to analyze whether Omalizumab response may be influenced by treatment duration. 340 severe asthmatics treated with Omalizumab for different periods of time were recruited. They were subdivided into 4 groups according to the Omalizumab treatment length: 60 months. Omalizumab treatment results (FEV 1 , exacerbations, ACT, SABA use, asthma control levels, medications used e and ICS doses) were compared. ACT, exacerbations, GINA control levels, ICS doses and SABA use were similar in all groups with different Omalizumab treatment durations. Using a linear regression model, corrected for all confounding variables, a higher significant positive increase in FEV 1 % in subjects treated for 12-24 (β = 9.49; p = 0.034) or 24-60 months (β = 8.56; p = 0.043) was found when compared with subjects treated for a shorter period. Treatment duration was positively associated with a step down of the other associated therapies (OR: 1.013; p = 0.019). This association was more relevant (OR: 4.167; p = 0.005) when we considered Omalizumab treatment duration >60 months compared to the shorter therapy. In particular, the percentage of subjects that were taking Montelukast, LABAs and oral corticosteroids was lower in the group treated with Omalizumab for a longer period of time. In real-life, the positive Omalizumab response remained stable for over 60 months. Long term Omalizumab treatment may lead to a discontinuation of some associated medications and to a slowing down of FEV 1 decline. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. A multi-level variable neighborhood search heuristic for a practical vehicle routing and driver scheduling problem

    DEFF Research Database (Denmark)

    Wen, Min; Krapper, Emil; Larsen, Jesper

    things, predefined workdays, fixed starting time, maximum weekly working duration, break rule. The objective is to minimize the total delivery cost. The real-life case study is fi rst introduced and modelled as a mixed integer linear program. A multilevel variable neighborhood search heuristic...... is then proposed for the problem. At the first level, the problem size is reduced through an aggregation procedure. At the second level, the aggregated weekly planning problem is decomposed into daily planning problems, each of which is solved by a variable neighborhood search. At the last level, the solution...

  5. A set packing inspired method for real-time junction train routing

    DEFF Research Database (Denmark)

    Lusby, Richard Martin; Larsen, Jesper; Ehrgott, Matthias

    2013-01-01

    Efficiently coordinating the often large number of interdependent, timetabled train movements on a railway junction, while satisfying a number of operational requirements, is one of the most important problems faced by a railway company. The most critical variant of the problem arises on a daily...... basis at major railway junctions where disruptions to rail traffic make the planned schedule/routing infeasible and rolling stock planners are forced to re-schedule/re-route trains in order to recover feasibility. The dynamic nature of the problem means that good solutions must be obtained quickly....... In this paper we describe a set packing inspired formulation of this problem and develop a branch-and-price based solution approach. A real life test instance arising in Germany and supplied by the major German railway company, Deutsche Bahn, indicates the efficiency of the proposed approach by confirming...

  6. A Set Packing Inspired Method for Real-Time Junction Train Routing

    DEFF Research Database (Denmark)

    Lusby, Richard Martin; Larsen, Jesper; Ehrgott, Matthias

    Efficiently coordinating the often large number of interdependent, timetabled train movements on a railway junction, while satisfying a number of operational requirements, is one of the most important problems faced by a railway company. The most critical variant of the problem arises on a daily...... basis at major railway junctions where disruptions to rail traffi c make the planned schedule/routing infeasible and rolling stock planners are forced to reschedule/re-route trains in order to recover feasibility. The dynamic nature of the problem means that good solutions must be obtained quickly....... In this paper we describe a set packing inspired formulation of this problem and develop a branch-and-price based solution approach. A real life test instance arising in Germany and supplied by the major German railway company, Deutsche Bahn, indicates the efficiency of the proposed approach by confirming...

  7. A basic period approach to the economic lot scheduling problem with shelf life considerations

    NARCIS (Netherlands)

    Soman, C.A.; van Donk, D.P.; Gaalman, G.J.C.

    2004-01-01

    Almost all the research on the economic lot scheduling problem (ELSP) considering limited shelf life of products has assumed a common cycle approach and an unrealistic assumption of possibility of deliberately reducing the production rate. In many cases, like in food processing industry where

  8. Perceived motor problems in daily life: Focus group interviews with people with Noonan syndrome and their relatives

    NARCIS (Netherlands)

    Croonen, E.A.; Harmsen, M.; Burgt, I. van der; Draaisma, J.M.T.; Noordam, C.; Essink, M.; Nijhuis-Van der Sanden, M.W.G.

    2016-01-01

    Studies from a patient perspective on motor performance problems in Noonan syndrome in daily life are lacking. The aims of this study were to provide insight into the motor performance problems that people with Noonan syndrome and/or their relatives experienced, the major consequences they suffered,

  9. Omalizumab for severe allergic asthma in clinical trials and real-life studies: what we know and what we should address.

    Science.gov (United States)

    Caminati, Marco; Senna, Gianenrico; Guerriero, Massimo; Dama, Anna Rita; Chieco-Bianchi, Fulvia; Stefanizzi, Giorgia; Montagni, Marcello; Ridolo, Erminia

    2015-04-01

    Randomized clinical trials (RCTs) are the gold standard for the assessment of any therapeutic intervention. Real-life (R-L) studies are needed to verify the provided results beyond the experimental setting. This review aims at comparing RCTs and R-L studies on omalizumab in adult severe allergic asthma, in order to highlight the concurring results and the discordant/missing data. The results of a selective literature research, including "omalizumab, controlled studies, randomized trial, real-life studies" as key words are discussed. Though some similarities between RCTs and R-L studies strengthen omalizumab efficacy and safety outcomes, significant differences concerning study population features, follow-up duration, local adverse events and drop-out rate for treatment inefficacy emerge between the two study categories. Furthermore the comparative analysis between RCTs and R-L studies highlights the need for further research, concerning in particular long-term effects of omalizumab and its impact on asthma comorbidities. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Description of Anomalous Noise Events for Reliable Dynamic Traffic Noise Mapping in Real-Life Urban and Suburban Soundscapes

    Directory of Open Access Journals (Sweden)

    Francesc Alías

    2017-02-01

    Full Text Available Traffic noise is one of the main pollutants in urban and suburban areas. European authorities have driven several initiatives to study, prevent and reduce the effects of exposure of population to traffic. Recent technological advances have allowed the dynamic computation of noise levels by means of Wireless Acoustic Sensor Networks (WASN such as that developed within the European LIFE DYNAMAP project. Those WASN should be capable of detecting and discarding non-desired sound sources from road traffic noise, denoted as anomalous noise events (ANE, in order to generate reliable noise level maps. Due to the local, occasional and diverse nature of ANE, some works have opted to artificially build ANE databases at the cost of misrepresentation. This work presents the production and analysis of a real-life environmental audio database in two urban and suburban areas specifically conceived for anomalous noise events’ collection. A total of 9 h 8 min of labelled audio data is obtained differentiating among road traffic noise, background city noise and ANE. After delimiting their boundaries manually, the acoustic salience of the ANE samples is automatically computed as a contextual signal-to-noise ratio (SNR. The analysis of the real-life environmental database shows high diversity of ANEs in terms of occurrences, durations and SNRs, as well as confirming both the expected differences between the urban and suburban soundscapes in terms of occurrences and SNRs, and the rare nature of ANE.

  11. Project selection problem under uncertainty: An application of utility theory and chance constrained programming to a real case

    Directory of Open Access Journals (Sweden)

    Reza Hosnavi Atashgah

    2013-06-01

    Full Text Available Selecting from a pool of interdependent projects under certainty, when faced with resource constraints, has been studied well in the literature of project selection problem. After briefly reviewing and discussing popular modeling approaches for dealing with uncertainty, this paper proposes an approach based on chance constrained programming and utility theory for a certain range of problems and under some practical assumptions. Expected Utility Programming, as the proposed modeling approach, will be compared with other well-known methods and its meaningfulness and usefulness will be illustrated via two numerical examples and one real case.

  12. Real life experimental determination of platinum group metals content in automotive catalytic converters

    Science.gov (United States)

    Yakoumis, I.; Moschovi, A. M.; Giannopoulou, I.; Panias, D.

    2018-03-01

    The real life experimental protocol for the preparation of spent automobile catalyst samples for elemental analysis is thoroughly described in the following study. Collection, sorting and dismantling, homogenization and sample preparation for X-Ray fluorescence spectroscopy and Atomic Adsorption Spectroscopy combined with Inductive coupled plasma mass spectrometry are discussed in detail for both ceramic and metallic spent catalysts. The concentrations of Platinum Group Metals (PGMs) in spent catalytic converters are presented based on typical consignments of recycled converters (more than 45,000 pieces) from the Greek Market. The conclusions clearly denoted commercial metallic catalytic foil contains higher PGMs loading than ceramic honeycombs. On the other hand, the total PGMs loading in spent ceramic catalytic converters has been found higher than the corresponding value for the metallic ones.

  13. Research on the optimization of quota design in real estate

    Science.gov (United States)

    Sun, Chunling; Ma, Susu; Zhong, Weichao

    2017-11-01

    Quota design is one of the effective methods of cost control in real estate development project and widely used in the current real estate development project to control the engineering construction cost, but quota design have many deficiencies in design process. For this purpose, this paper put forward a method to achieve investment control of real estate development project, which combine quota design and value engineering(VE) at the stage of design. Specifically, it’s an optimizing for the structure of quota design. At first, determine the design limits by investment estimate value, then using VE to carry on initial allocation of design limits and gain the functional target cost, finally, consider the whole life cycle cost (LCC) and operational problem in practical application to finish complex correction for the functional target cost. The improved process can control the project cost more effectively. It not only can control investment in a certain range, but also make the project realize maximum value within investment.

  14. The impact of real life treatment strategies for Candida peritonitis-A retrospective analysis.

    Science.gov (United States)

    Dubler, S; Laun, M; Koch, C; Hecker, A; Weiterer, S; Siegler, B H; Röhrig, R; Weigand, M A; Lichtenstern, C

    2017-07-01

    Candida species are commonly detected isolates from abdominal foci. The question remains as to who would benefit from early empiric treatment in cases of Candida peritonitis. This study collected real-life data on critically ill patients with Candida peritonitis to estimate the relevance of the chosen treatment strategy on the outcome of these patients. One hundred and thirty-seven surgical intensive care unit (ICU) patients with intra-abdominal invasive Candidiasis were included in the study. Fifty-six patients did not get any antifungal agent. Twenty-nine patients were empirically treated, and 52 patients were specifically treated. In the group without, with empiric and with specific antifungal treatment, the 30-day mortality rate was 33.9, 48.3 and 44.2 respectively. Candida albicans was the most frequently found species. Seven patients in the specific treatment group and one patient in the empiric treatment group emerged with candidaemia. Age, leucocyte count, APACHE II Score and acute liver failure were independent predictors of 30-day mortality in patients with Candida peritonitis. Not all patients with Candida peritonitis received antifungal treatment in real clinical practice. Patients with higher morbidity more often got antifungals. Early empirical therapy has not been associated with a better 30-day mortality. © 2017 Blackwell Verlag GmbH.

  15. Solution Methods for the Periodic Petrol Station Replenishment Problem

    Directory of Open Access Journals (Sweden)

    C Triki

    2013-12-01

    Full Text Available In this paper we introduce the Periodic Petrol Station Replenishment Problem (PPSRP over a T-day planning horizon and describe four heuristic methods for its solution. Even though all the proposed heuristics belong to the common partitioning-then-routing paradigm, they differ in assigning the stations to each day of the horizon. The resulting daily routing problems are then solved exactly until achieving optimalization. Moreover, an improvement procedure is also developed with the aim of ensuring a better quality solution. Our heuristics are tested and compared in two real-life cases, and our computational results show encouraging improvements with respect to a human planning solution

  16. The Relationship between Satisfaction with Life, ADHD Symptoms, and Associated Problems among University Students

    Science.gov (United States)

    Gudjonsson, Gisli H.; Sigurdsson, Jon Fridrik; Eyjolfsdottir, Gudrun Agusta; Smari, Jakob; Young, Susan

    2009-01-01

    Objective: To ascertain whether ADHD symptoms, and associated problems, are negatively related to subjective well-being. Method: The Satisfaction With Life Scale (SWLS) was completed by 369 university students, along with the Reasoning & Rehabilitation (R&R) ADHD Training Evaluation (RATE), the "Diagnostic and Statistical Manual of…

  17. Evaluating a "Second Life" Problem-Based Learning (PBL) Demonstrator Project: What Can We Learn?

    Science.gov (United States)

    Beaumont, Chris; Savin-Baden, Maggi; Conradi, Emily; Poulton, Terry

    2014-01-01

    This article reports the findings of a demonstrator project to evaluate how effectively Immersive Virtual Worlds (IVWs) could support problem-based learning. The project designed, created and evaluated eight scenarios within "Second Life" (SL) for undergraduate courses in health care management and paramedic training. Evaluation was…

  18. Optimal Housing, Consumption, and Investment Decisions over the Life Cycle

    DEFF Research Database (Denmark)

    Kraft, Holger; Munk, Claus

    2011-01-01

    We derive explicit solutions to life-cycle utility maximization problems involving stock and bond investment, perishable consumption, and the rental and ownership of residential real estate. Prices of houses, stocks and bonds, and labor income are correlated. Because of a positive correlation...... between house prices and labor income, young individuals want little exposure to house price risk and tend to rent their home. Later in life the desired housing investment increases and will eventually reach and exceed the desired consumption, suggesting that the individual should buy his home—and either...... additional housing units (for renting out) or house price–linked financial assets. In the final years, preferences shift back to home rental. The derived strategies are still useful if housing positions are only reset infrequently. Our results suggest that markets for real estate investment trusts or other...

  19. Using Dynamic Geometry and Computer Algebra Systems in Problem Based Courses for Future Engineers

    Science.gov (United States)

    Tomiczková, Svetlana; Lávicka, Miroslav

    2015-01-01

    It is a modern trend today when formulating the curriculum of a geometric course at the technical universities to start from a real-life problem originated in technical praxis and subsequently to define which geometric theories and which skills are necessary for its solving. Nowadays, interactive and dynamic geometry software plays a more and more…

  20. On real structures on rigid surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Kulikov, Vik S [Steklov Mathematical Institute, Russian Academy of Sciences (Russian Federation); Kharlamov, V M [Institut de Recherche Matematique Avanee Universite Louis Pasteur et CNRS 7 rue Rene Descartes (France)

    2002-02-28

    We construct examples of rigid surfaces (that is, surfaces whose deformation class consists of a unique surface) with a particular behaviour with respect to real structures. In one example the surface has no real structure. In another it has a unique real structure, which is not maximal with respect to the Smith-Thom inequality. These examples give negative answers to the following problems: the existence of real surfaces in each deformation class of complex surfaces, and the existence of maximal real surfaces in every complex deformation class that contains real surfaces. Moreover, we prove that there are no real surfaces among surfaces of general type with p{sub g}=q=0 and K{sup 2}=9. These surfaces also provide new counterexamples to the 'Dif = Def' problem.

  1. Improved Ant Colony Optimization for Seafood Product Delivery Routing Problem

    Directory of Open Access Journals (Sweden)

    Baozhen Yao

    2014-02-01

    Full Text Available This paper deals with a real-life vehicle delivery routing problem, which is a seafood product delivery routing problem. Considering the features of the seafood product delivery routing problem, this paper formulated this problem as a multi-depot open vehicle routing problem. Since the multi-depot open vehicle routing problem is a very complex problem, a method is used to reduce the complexity of the problem by changing the multi-depot open vehicle routing problem into an open vehicle routing problem with a dummy central depot in this paper. Then, ant colony optimization is used to solve the problem. To improve the performance of the algorithm, crossover operation and some adaptive strategies are used. Finally, the computational results for the benchmark problems of the multi-depot vehicle routing problem indicate that the proposed ant colony optimization is an effective method to solve the multi-depot vehicle routing problem. Furthermore, the computation results of the seafood product delivery problem from Dalian, China also suggest that the proposed ant colony optimization is feasible to solve the seafood product delivery routing problem.

  2. A Branch and Cut algorithm for the container shipping network design problem

    DEFF Research Database (Denmark)

    Reinhardt, Line Blander; Kallehauge, Brian; Pisinger, David

    The network design problem in liner shipping is of increasing importance in a strongly competitive market where potential cost reductions can influence market share and profits significantly. In this paper the network design and fleet assignment problems are combined into a mixed integer linear...... programming model minimizing the overall cost. To better reflect the real-life situation we take into account the cost of transhipment, a heterogeneous fleet, route dependant capacities, and butterfly routes. To the best of our knowledge it is the first time an exact solution method to the problem considers...... transhipment cost. The problem is solved with branch-and-cut using clover and transhipment inequalities. Computational results are reported for instances with up to 15 ports....

  3. Integrated Concentration in Science (iCons): Undergraduate Education Through Interdisciplinary, Team-Based, Real-World Problem Solving

    Science.gov (United States)

    Tuominen, Mark

    2013-03-01

    Attitude, Skills, Knowledge (ASK) - In this order, these are fundamental characteristics of scientific innovators. Through first-hand practice in using science to unpack and solve complex real-world problems, students can become self-motivated scientific leaders. This presentation describes the pedagogy of a recently developed interdisciplinary undergraduate science education program at the University of Massachusetts Amherst focused on addressing global challenges with scientific solutions. Integrated Concentration in Science (iCons) is an overarching concentration program that supplements the curricula provided within each student's chosen major. iCons is a platform for students to perform student-led research in interdisciplinary collaborative teams. With a schedule of one course per year over four years, the cohort of students move through case studies, analysis of real-world problems, development of potential solutions, integrative communication, laboratory practice, and capstone research projects. In this presentation, a track emphasizing renewable energy science is used to illustrate the iCons pedagogical methods. This includes discussion of a third-year laboratory course in renewable energy that is educationally scaffolded: beginning with a boot camp in laboratory techniques and culminating with student-designed research projects. Among other objectives, this course emphasizes the practice of using reflection and redesign, as a means of generating better solutions and embedding learning for the long term. This work is supported in part by NSF grant DUE-1140805.

  4. Concepts of real time and semi-real time material control

    International Nuclear Information System (INIS)

    Lovett, J.E.

    1975-01-01

    After a brief consideration of the traditional material balance accounting on an MBA basis, this paper explores the basic concepts of real time and semi-real time material control, together with some of the major problems to be solved. Three types of short-term material control are discussed: storage, batch processing, and continuous processing. (DLC)

  5. Peer Victimization among Classmates—Associations with Students’ Internalizing Problems, Self-Esteem, and Life Satisfaction

    Directory of Open Access Journals (Sweden)

    Sara B. Låftman

    2017-10-01

    Full Text Available Bullying is a major problem in schools and a large number of studies have demonstrated that victims have a high excess risk of poor mental health. It may however also affect those who are not directly victimized by peers. The present study investigates whether peer victimization among classmates is linked to internalizing problems, self-esteem, and life satisfaction at the individual level, when the student’s own victimization has been taken into account. The data were derived from the first wave of the Swedish part of Youth in Europe Study (YES!, including information on 4319 students in grade 8 (14–15 years of age distributed across 242 classes. Results from multilevel analyses show a significant association between classes with a high proportion of students being victimized and higher levels of internalizing problems, lower self-esteem, and lower life satisfaction at the student level. This association holds when the student’s own victimization has been taken into account. This suggests that peer victimization negatively affects those who are directly exposed, as well as their classmates. We conclude that efficient methods and interventions to reduce bullying in school are likely to benefit not only those who are victimized, but all students.

  6. Detection of Common Problems in Real-Time and Multicore Systems Using Model-Based Constraints

    Directory of Open Access Journals (Sweden)

    Raphaël Beamonte

    2016-01-01

    Full Text Available Multicore systems are complex in that multiple processes are running concurrently and can interfere with each other. Real-time systems add on top of that time constraints, making results invalid as soon as a deadline has been missed. Tracing is often the most reliable and accurate tool available to study and understand those systems. However, tracing requires that users understand the kernel events and their meaning. It is therefore not very accessible. Using modeling to generate source code or represent applications’ workflow is handy for developers and has emerged as part of the model-driven development methodology. In this paper, we propose a new approach to system analysis using model-based constraints, on top of userspace and kernel traces. We introduce the constraints representation and how traces can be used to follow the application’s workflow and check the constraints we set on the model. We then present a number of common problems that we encountered in real-time and multicore systems and describe how our model-based constraints could have helped to save time by automatically identifying the unwanted behavior.

  7. Impact of chronic urticaria on quality of life and work in Japan: Results of a real-world study.

    Science.gov (United States)

    Itakura, Asako; Tani, Yumiko; Kaneko, Naoko; Hide, Michihiro

    2018-06-13

    Little attention has been given to the burden of chronic urticaria (CU) in Japan compared with other skin diseases, such as atopic dermatitis (AD) and psoriasis. The primary objective of the RELEASE study was to evaluate the real-life quality-of-life impairment in CU patients in Japan. Data were collected from 1443 urticaria, 1668 AD and 435 psoriatic patients; 552 urticaria patients who presented urticaria symptoms for over 6 weeks were defined as CU. The mean Dermatology Life Quality Index (DLQI) total score was 4.8, 6.1 and 4.8 in CU, AD and psoriatic patients, respectively. Disease control of urticaria evaluated by the Urticaria Control Test (UCT) and DLQI exhibited a strong correlation with a Spearman's rank correlation coefficient of -0.7158. CU and AD patients had relatively higher scores in all Work Productivity and Activity Impairment - General Health subscales except for absenteeism. At the time of the survey, approximately 64% of CU patients reported UCT scores of <12 and demonstrated higher work productivity loss and activity impairment versus patients with UCT scores of ≥12. Patients with lower UCT scores also displayed a higher percentage of dissatisfaction with their health state and the treatment they received. Approximately 85% of patients with CU had visited dermatology clinics, and less than 20% had visited hospital, indicating existence of a highly burdened population outside specialized centers. These results highlight the unmet medical needs of CU patients, suggesting the need to increase awareness of CU burden among both physicians and patients and to pursue improved real-life patient care. © 2018 Novartis K.K. The Journal of Dermatology published by John Wiley & Sons Australia, Ltd on behalf of Japanese Dermatological Association.

  8. Real solutions to equations from geometry

    CERN Document Server

    Sottile, Frank

    2011-01-01

    Understanding, finding, or even deciding on the existence of real solutions to a system of equations is a difficult problem with many applications outside of mathematics. While it is hopeless to expect much in general, we know a surprising amount about these questions for systems which possess additional structure often coming from geometry. This book focuses on equations from toric varieties and Grassmannians. Not only is much known about these, but such equations are common in applications. There are three main themes: upper bounds on the number of real solutions, lower bounds on the number of real solutions, and geometric problems that can have all solutions be real. The book begins with an overview, giving background on real solutions to univariate polynomials and the geometry of sparse polynomial systems. The first half of the book concludes with fewnomial upper bounds and with lower bounds to sparse polynomial systems. The second half of the book begins by sampling some geometric problems for which all ...

  9. Comparative life cycle assessment of real pilot reactors for microalgae cultivation in different seasons

    International Nuclear Information System (INIS)

    Pérez-López, Paula; De Vree, Jeroen H.; Feijoo, Gumersindo; Bosma, Rouke; Barbosa, Maria J.; Moreira, María Teresa; Wijffels, René H.; Van Boxtel, Anton J.B.; Kleinegris, Dorinde M.M.

    2017-01-01

    Highlights: •Life cycle assessment was used to compare 3 real pilot systems for algae cultivation. •The temperature control system was the main contributor to environmental impacts. •Tubular reactors had lower impacts per unit of biomass produced than open pond. •Meteorological conditions on the reactors played a critical role in LCA results. •Environmental impact reductions of 17–90% were estimated for optimized full-scale reactors. -- Abstract: Microalgae are promising natural resources for biofuels, chemical, food and feed products. Besides their economic potential, the environmental sustainability must be examined. Cultivation has a significant environmental impact that depends on reactor selection and operating conditions. To identify the main environmental bottlenecks for scale-up to industrial facilities this study provides a comparative life cycle assessment (LCA) of open raceway ponds and tubular photobioreactors at pilot scale. The results are based on experimental data from real pilot plants operated in summer, fall and winter at AlgaePARC (Wageningen, The Netherlands). The energy consumption for temperature regulation presented the highest environmental burden. The production of nutrients affected some categories. Despite limited differences compared to the vertical system, the horizontal PBR was found the most efficient in terms of productivity and environmental impact. The ORP was, given the Dutch climatic conditions, only feasible under summer operation. The results highlight the relevance of LCA as a tool for decision-making in process design. Weather conditions and availability of sources for temperature regulation were identified as essential factors for the selection of geographic locations and for microalgal cultivation systems based on environmental criteria. Simulation of large-scale reactors with optimized temperature regulation systems lead to environmental improvements and energy demand reductions ranging from 17% up to 90% for

  10. Acceptance Sampling Plans Based on Truncated Life Tests for Sushila Distribution

    Directory of Open Access Journals (Sweden)

    Amer Ibrahim Al-Omari

    2018-03-01

    Full Text Available An acceptance sampling plan problem based on truncated life tests when the lifetime following a Sushila distribution is considered in this paper. For various acceptance numbers, confidence levels and values of the ratio between fixed experiment time and particular mean lifetime, the minimum sample sizes required to ascertain a specified mean life were found. The operating characteristic function values of the suggested sampling plans and the producer’s risk are presented. Some tables are provided and the results are illustrated by an example of a real data set.

  11. Partially specified physics problems: university students' attitudes and performance

    Energy Technology Data Exchange (ETDEWEB)

    Marusic, M [Prva Gimnazija, Teslina 10, 21000 Split (Croatia); Erceg, N [Department of Physics, University of Rijeka, Omladinska 14, 51000 Rijeka (Croatia); Slisko, J, E-mail: mirko@marusic.inf, E-mail: nerceg@phy.uniri.hr, E-mail: jslisko@fcfm.buap.mx [Benemerita Universidad Autonoma de Puebla, Apartado Postal 1152, Puebla, Puebla CP 72000 (Mexico)

    2011-05-15

    In this research we asked the fourth year students (N = 50) of a technical faculty of the University of Split (Republic of Croatia) to solve a partially specified physics problem related to gravitational force. The task for the students was to decide whether the situation described in the problem is feasible or not. Nevertheless, the formulation of the problem is such that it does not give students any explicit advice regarding what to calculate or how to judge the feasibility of the given situation in the real world. The research was carried out using a structured written exam method. The worksheet was structured in order to assess explicitly a few elements of the students' problem-solving performance. Based on their results, the examinees were classified into four categories, depending on what they could or could not accomplish during problem solving. A majority of students were not able to solve the given physical problem completely. A selection of students' and professors' observations is also included. Our results show that traditionally formulated numerical exercises, which are mostly used in physics teaching, do not develop students' abilities in higher-order thinking (i.e. planning, decision making or result evaluation) to a desirable extent. We suggest that partially specified problems should be given to students, both in problem-solving sessions and exams, in order to prepare them for dealing with ill-structured tasks in real life.

  12. Spatial Transformation of Equality – Generalized Travelling Salesman Problem to Travelling Salesman Problem

    Directory of Open Access Journals (Sweden)

    Mohammed Zia

    2018-03-01

    Full Text Available The Equality-Generalized Travelling Salesman Problem (E-GTSP, which is an extension of the Travelling Salesman Problem (TSP, is stated as follows: given groups of points within a city, like banks, supermarkets, etc., find a minimum cost Hamiltonian cycle that visits each group exactly once. It can model many real-life combinatorial optimization scenarios more efficiently than TSP. This study presents five spatially driven search-algorithms for possible transformation of E-GTSP to TSP by considering the spatial spread of points in a given urban city. Presented algorithms are tested over 15 different cities, classified by their street-network’s fractal-dimension. Obtained results denote that the R-Search algorithm, which selects the points from each group based on their radial separation with respect to the start–end point, is the best search criterion for any E-GTSP to TSP conversion modelled for a city street network. An 8.8% length error has been reported for this algorithm.

  13. A heterogeneous fleet vehicle routing model for solving the LPG distribution problem: A case study

    International Nuclear Information System (INIS)

    Onut, S; Kamber, M R; Altay, G

    2014-01-01

    Vehicle Routing Problem (VRP) is an important management problem in the field of distribution and logistics. In VRPs, routes from a distribution point to geographically distributed points are designed with minimum cost and considering customer demands. All points should be visited only once and by one vehicle in one route. Total demand in one route should not exceed the capacity of the vehicle that assigned to that route. VRPs are varied due to real life constraints related to vehicle types, number of depots, transportation conditions and time periods, etc. Heterogeneous fleet vehicle routing problem is a kind of VRP that vehicles have different capacity and costs. There are two types of vehicles in our problem. In this study, it is used the real world data and obtained from a company that operates in LPG sector in Turkey. An optimization model is established for planning daily routes and assigned vehicles. The model is solved by GAMS and optimal solution is found in a reasonable time

  14. A heterogeneous fleet vehicle routing model for solving the LPG distribution problem: A case study

    Science.gov (United States)

    Onut, S.; Kamber, M. R.; Altay, G.

    2014-03-01

    Vehicle Routing Problem (VRP) is an important management problem in the field of distribution and logistics. In VRPs, routes from a distribution point to geographically distributed points are designed with minimum cost and considering customer demands. All points should be visited only once and by one vehicle in one route. Total demand in one route should not exceed the capacity of the vehicle that assigned to that route. VRPs are varied due to real life constraints related to vehicle types, number of depots, transportation conditions and time periods, etc. Heterogeneous fleet vehicle routing problem is a kind of VRP that vehicles have different capacity and costs. There are two types of vehicles in our problem. In this study, it is used the real world data and obtained from a company that operates in LPG sector in Turkey. An optimization model is established for planning daily routes and assigned vehicles. The model is solved by GAMS and optimal solution is found in a reasonable time.

  15. Real-life decision making in college students. I: Consistency across specific decisions.

    Science.gov (United States)

    Galotti, Kathleen M; Wiener, Hillary J D; Tandler, Jane M

    2014-01-01

    First-year undergraduates participated in a short-term longitudinal study of real-life decision making over their first 14 months of college. They were surveyed about 7 different decisions: choosing courses for an upcoming term (3 different terms), choosing an academic major (twice), planning for the upcoming summer, and planning for sophomore-year housing. Participants showed moderate levels of consistency in the options they considered and in the criteria they used to decide between options, with about half of the options or criteria being used at 2 different points on the decision repeatedly studied. Participants varied somewhat in structural consistency, the tendency to consider the same number of options or criteria across decisions. They also varied in the way they integrated information across decision-making tasks. We suggest that people attempt to keep the information demands of the task within workable limits, sometimes sacrificing consistency as a result.

  16. Coping, problem solving, depression, and health-related quality of life in patients receiving outpatient stroke rehabilitation.

    Science.gov (United States)

    Visser, Marieke M; Heijenbrok-Kal, Majanka H; Spijker, Adriaan Van't; Oostra, Kristine M; Busschbach, Jan J; Ribbers, Gerard M

    2015-08-01

    To investigate whether patients with high and low depression scores after stroke use different coping strategies and problem-solving skills and whether these variables are related to psychosocial health-related quality of life (HRQOL) independent of depression. Cross-sectional study. Two rehabilitation centers. Patients participating in outpatient stroke rehabilitation (N=166; mean age, 53.06±10.19y; 53% men; median time poststroke, 7.29mo). Not applicable. Coping strategy was measured using the Coping Inventory for Stressful Situations; problem-solving skills were measured using the Social Problem Solving Inventory-Revised: Short Form; depression was assessed using the Center for Epidemiologic Studies Depression Scale; and HRQOL was measured using the five-level EuroQol five-dimensional questionnaire and the Stroke-Specific Quality of Life Scale. Independent samples t tests and multivariable regression analyses, adjusted for patient characteristics, were performed. Compared with patients with low depression scores, patients with high depression scores used less positive problem orientation (P=.002) and emotion-oriented coping (Pproblem orientation (Pproblem orientation was independently related to psychosocial HRQOL (β=.086; P=.018) and total HRQOL (β=.058; P=.031). Patients with high depression scores use different coping strategies and problem-solving skills than do patients with low depression scores. Independent of depression, positive problem-solving skills appear to be most significantly related to better HRQOL. Copyright © 2015 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  17. Private Data -- The Real Story: A Huge Problem with Education Research

    Directory of Open Access Journals (Sweden)

    R. James Milgram

    2012-12-01

    Full Text Available A very influential paper on improving math outcomes was published in 2008. The authors refused to divulge their data claiming that agreements with the schools and Family Educational Rights and Privacy Act rules (FERPA prevented it.● It turns out that this is not true.● The claimed legal foundations do not say what these authors said they do, this this is a widespread misconception among education researchers.When we found the identities of the schools by other means, serious problems with the conclusions of the article were quickly revealed.● The 2008 paper was far from unique in this respect.● There are many papers that have had enormous influences on K-12 mathematics curricula, and could not be independently verified because the authors refused to reveal their data.In this article we describe how we were able to find the real data for the 2008 paper, and point out the legal constraints that should make it very difficult for authors of such papers to withhold their data in the future.

  18. Reversal of Dabigatran Using Idarucizumab in a Septic Patient with Impaired Kidney Function in Real-Life Practice

    Directory of Open Access Journals (Sweden)

    Thomas C. Sauter

    2016-01-01

    Full Text Available Background. Immediate reversal of anticoagulation is essential when facing severe bleeding or emergency surgery. Although idarucizumab is approved for the reversal of dabigatran in many countries, clinical experiences are lacking, particularly in special patient-populations such as sepsis and impaired renal function. Case Presentation. We present the case of a 67-year-old male septic patient with a multilocular facial abscess and chronic kidney disease (GFR 36.5 mL/min. Thrombin time (TT and activated partial thromboplastin time (aPTT 15 hours after the last intake of 150 mg dabigatran were both prolonged (>120 sec, resp., 61 sec, as well as unbound dabigatran concentration (119.05 ng/mL. Before immediate emergency surgery dabigatran was antagonised using idarucizumab 2 × 2.5 g. Dabigatran concentration was not detectable 10 min after idarucizumab administration (<30 ng/mL. TT and aPTT time were normalised (16.2 sec, resp., 30.2 sec. Sepsis was controlled after surgery and kidney function remained stable. In the absence of postoperative bleeding, dabigatran was restarted 36 hours after admission. Conclusion. Idarucizumab successfully reversed the effect of dabigatran in real-life practice in a patient with sepsis and renal impairment and allowed emergency surgery with normal haemostasis. Efficacy and safety in real-life practice will nevertheless require prospective registries monitoring.

  19. Quality of life improvement in HIV-1 patients treated with raltegravir in a real-life observational study: RACING.

    Science.gov (United States)

    Spire, Bruno; Nait-Ighil, Lella; Pugliese, Pascal; Poizot-Martin, Isabelle; Jullien, Vincent; Marcelin, Anne-Geneviève; Billaud, Eric

    2017-01-01

    Good efficacy and safety of raltegravir in person living with HIV was demonstrated in clinical trials over five years, but real-life data, particularly about quality of life (QoL), are lacking. QoL was evaluated over time in adult patients first treated or switched to regimens containing raltegravir in an observational cohort study. Patient QoL was evaluated using the Fatigue Impact Scale (FIS) and the HIV Symptom Index (HSI). Data were collected at baseline and at 1, 3, 6, 12, 18, and 24 months. Baseline FIS and HSI subscores were compared with the scores at each visit using the paired Wilcoxon test. The impact of time, sociodemographic and medical variables upon patient-perceived fatigue and symptoms was also assessed using mixed multivariate models. From baseline, all FIS and HSI subscores improved significantly after one month of treatment. In addition, psychosocial FIS subscores and both the frequency of bothersome symptoms and HSI subscores improved significantly at each visit. Physical FIS subscores also improved significantly, except at month 18, whereas both cognitive and total FIS subscores improved only after 6 months and 24 months, respectively. In multivariate analysis, employment was independently associated over time with improved improvement in both FIS and HSI subscores. Patient QoL improved significantly over a 24-month period of treatment with a raltegravir-containing regimen. FIS and HSI are sensitive tools to measure the impact of new antiretroviral combinations on a patient's perception of QoL.

  20. Application of Neutrosophic Set Theory in Generalized Assignment Problem

    Directory of Open Access Journals (Sweden)

    Supriya Kar

    2015-09-01

    Full Text Available This paper presents the application of Neutrosophic Set Theory (NST in solving Generalized Assignment Problem (GAP. GAP has been solved earlier under fuzzy environment. NST is a generalization of the concept of classical set, fuzzy set, interval-valued fuzzy set, intuitionistic fuzzy set. Elements of Neutrosophic set are characterized by a truth-membership function, falsity and also indeterminacy which is a more realistic way of expressing the parameters in real life problem. Here the elements of the cost matrix for the GAP are considered as neutrosophic elements which have not been considered earlier by any other author. The problem has been solved by evaluating score function matrix and then solving it by Extremum Difference Method (EDM [1] to get the optimal assignment. The method has been demonstrated by a suitable numerical example.

  1. Decreased health-related quality of life in patients with diabetic foot problems

    Directory of Open Access Journals (Sweden)

    Sothornwit J

    2018-03-01

    Full Text Available Jin Sothornwit,1 Gulapar Srisawasdi,2 Atchara Suwannakin,2 Apiradee Sriwijitkamol1 1Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok Noi, Bangkok, Thailand; 2Foot Clinic, Department of Rehabilitation Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok Noi, Bangkok, Thailand Purpose: The aim of this study was to investigate health-related quality of life (HRQoL in patients with diabetic foot problems and compare the HRQoL between diabetic patients with: 1 diabetic foot problems (DF, including diabetic foot ulcer (DFU or amputation (AMPU; 2 other diabetic complications (COM, such as diabetic retinopathy (DR, end-stage renal disease (ESRD, or coronary artery disease (CAD; and 3 no diabetic complication (CON.Patients and methods: A total of 254 diabetic patients were studied in a cross-sectional setting. HRQoL was evaluated using Thai version of the Euro Quality of Life Questionnaire (EuroQoL, with five dimensions and five-level scale (EQ-5D-5L. Utility scores were calculated using time trade-off methods.Results: A total of 141 patients in the DF group (98 DFU and 43 AMPU groups, 82 in the COM group (27 DR, 28 ESRD, and 27 CAD groups, and 31 in the CON group were interviewed. The mean age was 63.2±12.1 years, body mass index was 24.9±4.7 kg/m2, mean hemoglobin A1c was 7.7±2.1%, duration of diabetes was 13.1±9.9 years, and the mean utility scores were 0.799±0.25. After having DF, 21% of patients had lost their jobs. The COM group had lower utility scores than the CON group. Among the diabetic complications, the DF group had the lowest mean utility scores as compared to the COM and CON groups (0.703±0.28 in the DF group, 0.903±0.15 in the COM group, and 0.961±0.06 in the CON group, P<0.01. There was no difference in the mean utility scores between DFU and AMPU groups. Patients in the DF group reported moderate-to-severe problem in all

  2. Surface enhanced raman spectroscopy analytical, biophysical and life science applications

    CERN Document Server

    Schlücker, Sebastian

    2013-01-01

    Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analytical and life science applications, this monograph shows how to apply surface-enhanced Raman scattering (SERS) for solving real world problems. From the contents: * Theory and practice of SERS * Analytical applications * SERS combined with other analytical techniques * Biophysical applications * Life science applications including various microscopies Aimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists. Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor-in-Chief of the Journal of Raman Spectroscopy.

  3. A Parallel Biological Optimization Algorithm to Solve the Unbalanced Assignment Problem Based on DNA Molecular Computing.

    Science.gov (United States)

    Wang, Zhaocai; Pu, Jun; Cao, Liling; Tan, Jian

    2015-10-23

    The unbalanced assignment problem (UAP) is to optimally resolve the problem of assigning n jobs to m individuals (m applied mathematics, having numerous real life applications. In this paper, we present a new parallel DNA algorithm for solving the unbalanced assignment problem using DNA molecular operations. We reasonably design flexible-length DNA strands representing different jobs and individuals, take appropriate steps, and get the solutions of the UAP in the proper length range and O(mn) time. We extend the application of DNA molecular operations and simultaneity to simplify the complexity of the computation.

  4. Deceleration during 'real life' motor vehicle collisions – a sensitive predictor for the risk of sustaining a cervical spine injury?

    Directory of Open Access Journals (Sweden)

    Hartwig Erich

    2009-03-01

    Full Text Available Abstract Background The predictive value of trauma impact for the severity of whiplash injuries has mainly been investigated in sled- and crash-test studies. However, very little data exist for real-life accidents. Therefore, the predictive value of the trauma impact as assessed by the change in velocity of the car due to the collision (ΔV for the resulting cervical spine injuries were investigated in 57 cases after real-life car accidents. Methods ΔV was determined for every car and clinical findings related to the cervical spine were assessed and classified according to the Quebec Task Force (QTF. Results In our study, 32 (56% subjects did not complain about symptoms and were therefore classified as QTF grade 0; 25 (44% patients complained of neck pain: 8 (14% were classified as QTF grade I, 6 (10% as QTF grade II, and 11 (19% as QTF grade IV. Only a slight correlation (r = 0.55 was found between the reported pain and ΔV. No relevant correlation was found between ΔV and the neck disability index (r = 0.46 and between ΔV and the QTF grade (r = 0.45 for any of the collision types. There was no ΔV threshold associated with acceptable sensitivity and specificity for the prognosis of a cervical spine injury. Conclusion The results of this study indicate that ΔV is not a conclusive predictor for cervical spine injury in real-life motor vehicle accidents. This is of importance for surgeons involved in medicolegal expertise jobs as well as patients who suffer from whiplash-associated disorders (WADs after motor vehicle accidents. Trial registration The study complied with applicable German law and with the principles of the Helsinki Declaration and was approved by the institutional ethics commission.

  5. An energy-efficient transmission scheme for real-time data in wireless sensor networks.

    Science.gov (United States)

    Kim, Jin-Woo; Barrado, José Ramón Ramos; Jeon, Dong-Keun

    2015-05-20

    The Internet of things (IoT) is a novel paradigm where all things or objects in daily life can communicate with other devices and provide services over the Internet. Things or objects need identifying, sensing, networking and processing capabilities to make the IoT paradigm a reality. The IEEE 802.15.4 standard is one of the main communication protocols proposed for the IoT. The IEEE 802.15.4 standard provides the guaranteed time slot (GTS) mechanism that supports the quality of service (QoS) for the real-time data transmission. In spite of some QoS features in IEEE 802.15.4 standard, the problem of end-to-end delay still remains. In order to solve this problem, we propose a cooperative medium access scheme (MAC) protocol for real-time data transmission. We also evaluate the performance of the proposed scheme through simulation. The simulation results demonstrate that the proposed scheme can improve the network performance.

  6. Plutonium: real and false problems

    International Nuclear Information System (INIS)

    Bemden, E. van den

    1981-01-01

    This paper deals with technical and technological state of the possibilities of using plutonium as fuel in the thermal and fast reactors. It also describes the political blockage restraining its use and the reasons for it. The accent is put on some fundamental lacks of international coordination and on some problems of commercial policy, which impede, in a certain way, the industrial use of plutonium as a fuel. (author)

  7. Issues of Application of Machine Learning Models for Virtual and Real-Life Buildings

    Directory of Open Access Journals (Sweden)

    Young Min Kim

    2016-06-01

    Full Text Available The current Building Energy Performance Simulation (BEPS tools are based on first principles. For the correct use of BEPS tools, simulationists should have an in-depth understanding of building physics, numerical methods, control logics of building systems, etc. However, it takes significant time and effort to develop a first principles-based simulation model for existing buildings—mainly due to the laborious process of data gathering, uncertain inputs, model calibration, etc. Rather than resorting to an expert’s effort, a data-driven approach (so-called “inverse” approach has received growing attention for the simulation of existing buildings. This paper reports a cross-comparison of three popular machine learning models (Artificial Neural Network (ANN, Support Vector Machine (SVM, and Gaussian Process (GP for predicting a chiller’s energy consumption in a virtual and a real-life building. The predictions based on the three models are sufficiently accurate compared to the virtual and real measurements. This paper addresses the following issues for the successful development of machine learning models: reproducibility, selection of inputs, training period, outlying data obtained from the building energy management system (BEMS, and validation of the models. From the result of this comparative study, it was found that SVM has a disadvantage in computation time compared to ANN and GP. GP is the most sensitive to a training period among the three models.

  8. Healthy food choices are happy food choices : evidence from a real life sample using smartphone based assessments

    OpenAIRE

    Wahl, Deborah R.; Villinger, Karoline; König, Laura M.; Ziesemer, Katrin; Schupp, Harald T.; Renner, Britta

    2017-01-01

    Research suggests that "healthy" food choices such as eating fruits and vegetables have not only physical but also mental health benefits and might be a long-term investment in future well-being. This view contrasts with the belief that high-caloric foods taste better, make us happy, and alleviate a negative mood. To provide a more comprehensive assessment of food choice and well-being, we investigated in-the-moment eating happiness by assessing complete, real life dietary behaviour across ei...

  9. A review on fuzzy and stochastic extensions of the multi index transportation problem

    Directory of Open Access Journals (Sweden)

    Singh Sungeeta

    2017-01-01

    Full Text Available The classical transportation problem (having source and destination as indices deals with the objective of minimizing a single criterion, i.e. cost of transporting a commodity. Additional indices such as commodities and modes of transport led to the Multi Index transportation problem. An additional fixed cost, independent of the units transported, led to the Multi Index Fixed Charge transportation problem. Criteria other than cost (such as time, profit etc. led to the Multi Index Bi-criteria transportation problem. The application of fuzzy and stochastic concept in the above transportation problems would enable researchers to not only introduce real life uncertainties but also obtain solutions of these transportation problems. The review article presents an organized study of the Multi Index transportation problem and its fuzzy and stochastic extensions till today, and aims to help researchers working with complex transportation problems.

  10. An IP Framework for the Crew Pairing Problem Using Subsequence Generation

    DEFF Research Database (Denmark)

    Rasmussen, Matias Sevel; Lusby, Richard Martin; Ryan, David

    In this paper we consider an important problem for the airline industry. The widely studied crew pairing problem is typically formulated as a set partitioning problem and solved using the branch-and-price methodology. Here we develop a new integer programming framework, based on the concept...... of subsequence generation, for solving the set partitioning formulation. In subsequence generation one restricts the number of permitted subsequent flights, that a crew member can turn to after completing any particular flight. By restricting the number of subsequences, the number of pairings in the problem...... decreases. The aim is then to dynamically add attractive subsequences to the problem, thereby increasing the number of possible pairings and improving the solution quality. Encouraging results are obtained on 19 real-life instances supplied by Air New Zealand and show that the described methodology...

  11. Solving the Single-Sink, Fixed-Charge, Multiple-Choice Transportation Problem by Dynamic Programming

    DEFF Research Database (Denmark)

    Rauff Lind Christensen, Tue; Klose, Andreas; Andersen, Kim Allan

    important aspects of supplier selection, an important application of the SSFCTP, this does not reflect the real life situation. First, transportation costs faced by many companies are in fact piecewise linear. Secondly, when suppliers offer discounts, either incremental or all-unit discounts, such savings......The Single-Sink, Fixed-Charge, Multiple-Choice Transportation Problem (SSFCMCTP) is a problem with versatile applications. This problem is a generalization of the Single-Sink, Fixed-Charge Transportation Problem (SSFCTP), which has a fixed-charge, linear cost structure. However, in at least two...... are neglected in the SSFCTP. The SSFCMCTP overcome this problem by incorporating a staircase cost structure in the cost function instead of the usual one used in SSFCTP. We present a dynamic programming algorithm for the resulting problem. To enhance the performance of the generic algorithm a number...

  12. Proposal for the 4th Workshop on Mobile Gaming, Mobile Life – Interweaving the Virtual and the Real

    OpenAIRE

    Grüter , Barbara; Mügge , Holger; Oppermann , Leif; Billinghurst , Mark

    2012-01-01

    Part 18: Mobile Gaming, Mobile Life - Interweaving the Virtual and the Real; International audience; Over the last few years we have witnessed the smartphone dominating the market, the rapid growth of mobile apps, a surge in mobile augmented reality and location-based apps, and burgeoning mobile communities. While mobile topics continue to provide rich research challenges, people and companies outside academia already use these apps regularly. This is due to the increased availability of affo...

  13. Constraint-Based Local Search for Constrained Optimum Paths Problems

    Science.gov (United States)

    Pham, Quang Dung; Deville, Yves; van Hentenryck, Pascal

    Constrained Optimum Path (COP) problems arise in many real-life applications and are ubiquitous in communication networks. They have been traditionally approached by dedicated algorithms, which are often hard to extend with side constraints and to apply widely. This paper proposes a constraint-based local search (CBLS) framework for COP applications, bringing the compositionality, reuse, and extensibility at the core of CBLS and CP systems. The modeling contribution is the ability to express compositional models for various COP applications at a high level of abstraction, while cleanly separating the model and the search procedure. The main technical contribution is a connected neighborhood based on rooted spanning trees to find high-quality solutions to COP problems. The framework, implemented in COMET, is applied to Resource Constrained Shortest Path (RCSP) problems (with and without side constraints) and to the edge-disjoint paths problem (EDP). Computational results show the potential significance of the approach.

  14. Rehabilitation of Executive Functions in a Real-Life Setting: Goal Management Training Applied to a Person with Schizophrenia

    Directory of Open Access Journals (Sweden)

    M.-N. Levaux

    2012-01-01

    Full Text Available The aim was to assess the efficacy of a modified version of Goal Management Training (GMT in a person with schizophrenia who had difficulties in attaining the final goal for new and multitasking daily-life situations. GMT is designed to improve abilities in establishing goal-directed plans and carrying them out effectively. Beneficial effects of GMT were measured for several clinical questionnaires, laboratory tasks, and three real-life situations: meal preparation (trained, familiar; washing (nontrained, familiar; meeting preparation (nontrained, unfamiliar. The results revealed improvement in planning and on trained laboratory and meal preparation tasks and a generalization of GMT effects on nontrained laboratory and everyday tasks. Self-esteem also improved. Finally, a two-year followup indicated the durability of the beneficial effects.

  15. A novel approach for inventory problem in the pharmaceutical supply chain.

    Science.gov (United States)

    Candan, Gökçe; Yazgan, Harun Reşit

    2016-02-24

    In pharmaceutical enterprises, keeping up with global market conditions is possible with properly selected supply chain management policies. Generally; demand-driven classical supply chain model is used in the pharmaceutical industry. In this study, a new mathematical model is developed to solve an inventory problem in the pharmaceutical supply chain. Unlike the studies in literature, the "shelf life and product transition times" constraints are considered, simultaneously, first time in the pharmaceutical production inventory problem. The problem is formulated as a mixed-integer linear programming (MILP) model with a hybrid time representation. The objective is to maximize total net profit. Effectiveness of the proposed model is illustrated considering a classical and a vendor managed inventory (VMI) supply chain on an experimental study. To show the effectiveness of the model, an experimental study is performed; which contains 2 different supply chain policy (Classical and VMI), 24 and 30 months planning horizon, 10 and 15 different cephalosporin products. Finally the mathematical model is compared to another model in literature and the results show that proposed model is superior. This study suggest a novel approach for solving pharmaceutical inventory problem. The developed model is maximizing total net profit while determining optimal production plan under shelf life and product transition constraints in the pharmaceutical industry. And we believe that the proposed model is much more closed to real life unlike the other studies in literature.

  16. Monoamine oxidase A polymorphism moderates stability of attention problems and susceptibility to life stress during adolescence.

    Science.gov (United States)

    Zohsel, K; Bianchi, V; Mascheretti, S; Hohm, E; Schmidt, M H; Esser, G; Brandeis, D; Banaschewski, T; Nobile, M; Laucht, M

    2015-11-01

    Attention problems affect a substantial number of children and adolescents and are predictive of academic underachievement and lower global adaptive functioning. Considerable variability has been observed with regard to the individual development of attention problems over time. In particular, the period of adolescence is characterized by substantial maturation of executive functioning including attentional processing, with the influence of genetic and environmental factors on individual trajectories not yet well understood. In the present investigation, we evaluated whether the monoamine oxidase A functional promoter polymorphism, MAOA-LPR, plays a role in determining continuity of parent-rated attention problems during adolescence. At the same time, a potential effect of severe life events (SLEs) was taken into account. A multi-group path analysis was used in a sample of 234 adolescents (149 males, 85 females) who took part in an epidemiological cohort study at the ages of 11 and 15 years. Attention problems during early adolescence were found to be a strong predictor of attention problems in middle adolescence. However, in carriers of the MAOA-LPR low-activity variant (MAOA-L), stability was found to be significantly higher than in carriers of the high-activity variant (MAOA-H). Additionally, only in MAOA-L carriers did SLEs during adolescence significantly impact on attention problems at the age of 15 years, implying a possible gene × environment interaction. To conclude, we found evidence that attention problems during adolescence in carriers of the MAOA-L allele are particularly stable and malleable to life stressors. The present results underline the usefulness of applying a more dynamic GxE perspective. © 2015 John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society.

  17. Comparison of three problem-based learning conditions (real patients, digital and paper) with lecture-based learning in a dermatology course: a prospective randomized study from China.

    Science.gov (United States)

    Li, Jie; Li, Qing Ling; Li, Ji; Chen, Ming Liang; Xie, Hong Fu; Li, Ya Ping; Chen, Xiang

    2013-01-01

    The precise effect and the quality of different cases used in dermatology problem-based learning (PBL) curricula are yet unclear. To prospectively compare the impact of real patients, digital, paper PBL (PPBL) and traditional lecture-based learning (LBL) on academic results and student perceptions. A total of 120 students were randomly allocated into either real-patients PBL (RPBL) group studied via real-patient cases, digital PBL (DPBL) group studied via digital-form cases, PPBL group studied via paper-form cases, or conventional group who received didactic lectures. Academic results were assessed through review of written examination, objective structured clinical examination and student performance scores. A five-point Likert scale questionnaire was used to evaluate student perceptions. Compared to those receiving lectures only, all PBL participants had better results for written examination, clinical examination and overall performance. Students in RPBL group exhibited better overall performance than those in the other two PBL groups. Real-patient cases were more effective in helping develop students' self-directed learning skills, improving their confidence in future patient encounters and encouraging them to learn more about the discussed condition, compared to digital and paper cases. Both real patient and digital triggers are helpful in improving students' clinical problem-handling skills. However, real patients provide greater benefits to students.

  18. Predictors for the initiation of a basal supported oral therapy (BOT) in type 2 diabetic patients under real-life conditions in Germany.

    Science.gov (United States)

    Kostev, Karel; Dippel, Franz-Werner

    2012-12-01

    To assess the predictors for the initiation of a basal supported oral therapy (BOT) in type 2 diabetic patients under real-life conditions in Germany. A historical cohort study based on representative German real life data (IMS(®) Disease Analyzer) was performed. The study included patients with type 2 diabetes who started an oral antidiabetic drug (OAD) treatment between 01/1995 and 12/2011. Patients with consecutive treatment data for at least 12 months before the initiation of an OAD treatment were eligible for the analysis. The time-dependent rate of patients starting an insulin therapy with a long-acting insulin was calculated by use of the Kaplan-Meier method. Multivariate Cox regression analyses were applied to identify associated factors. The study included 194,967 patients with type 2 diabetes mellitus being on OAD therapy. 24,964 patients were switched to BOT during the observational period. The probability of switching to insulin therapy was associated with three main predictors such as (1) poor metabolic control, (2) midlife age and (3) number and type of the OAD before insulinization. The variation of the HbA1c threshold to HbA1c≥7.5 leads to comparable outcomes with significant HR. The highest probability of initiating a basal supported oral therapy (BOT) under real life conditions was found for patients with poor metabolic control, midlife age and pre-treatment with specific OADs such as SU, GLI or AGI before initiation of insulin therapy. Copyright © 2012 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

  19. A robust decision-making approach for p-hub median location problems based on two-stage stochastic programming and mean-variance theory : a real case study

    NARCIS (Netherlands)

    Ahmadi, T.; Karimi, H.; Davoudpour, H.

    2015-01-01

    The stochastic location-allocation p-hub median problems are related to long-term decisions made in risky situations. Due to the importance of this type of problems in real-world applications, the authors were motivated to propose an approach to obtain more reliable policies in stochastic

  20. Who Am I? A Life Story Intervention for Persons With Intellectual Disability and Psychiatric Problems

    NARCIS (Netherlands)

    Westerhof, Gerben Johan; Beernink, Janny; Sools, Anna Maria

    2016-01-01

    This article describes an innovative intervention based on narrative and life review therapy that is tailored to people with intellectual disability (ID) and psychiatric problems. The current study provides a first evaluation of the intervention. A symptom checklist (SCL-90) was used in a pre- and

  1. Family factors and life events as risk factors for behavioural and emotional problems in children

    NARCIS (Netherlands)

    Harland, P.; Reijneveld, S.A.; Brugman, E.; Verloove-Vanhorick, S.P.; Verhulst, F.C.

    2002-01-01

    Abstract The aim of this study was to identify groups of children at increased risk of behavioural or emotional problems on the basis of socio-demographic characteristics, family characteristics, and recent life events with a focus on unemployment and divorce or separation. We obtained data on the

  2. Comparing the happiness effects of real and on-line friends.

    Directory of Open Access Journals (Sweden)

    John F Helliwell

    Full Text Available A recent large Canadian survey permits us to compare face-to-face ('real-life' and on-line social networks as sources of subjective well-being. The sample of 5,000 is drawn randomly from an on-line pool of respondents, a group well placed to have and value on-line friendships. We find three key results. First, the number of real-life friends is positively correlated with subjective well-being (SWB even after controlling for income, demographic variables and personality differences. Doubling the number of friends in real life has an equivalent effect on well-being as a 50% increase in income. Second, the size of online networks is largely uncorrelated with subjective well-being. Third, we find that real-life friends are much more important for people who are single, divorced, separated or widowed than they are for people who are married or living with a partner. Findings from large international surveys (the European Social Surveys 2002-2008 are used to confirm the importance of real-life social networks to SWB; they also indicate a significantly smaller value of social networks to married or partnered couples.

  3. Safety and efficacy of venom immunotherapy: a real life study.

    Science.gov (United States)

    Kołaczek, Agnieszka; Skorupa, Dawid; Antczak-Marczak, Monika; Kuna, Piotr; Kupczyk, Maciej

    2017-04-01

    Venom immunotherapy (VIT) is recommended as the first-line treatment for patients allergic to Hymenoptera venom. To analyze the safety and efficacy of VIT in a real life setting. One hundred and eighty patients undergoing VIT were studied to evaluate the safety, efficacy, incidence and nature of symptoms after field stings and adverse reactions to VIT. Significantly more patients were allergic to wasp than bee venom (146 vs. 34, p bees, and were not associated with angiotensin convertase inhibitors (ACEi) or β-adrenergic antagonists use. Systemic reactions were observed in 4 individuals on wasp VIT (2.7%) and in 6 patients allergic to bees (17.65%). The VIT was efficacious as most patients reported no reactions (50%) or reported only mild local reactions (43.75%) to field stings. The decrease in sIgE at completion of VIT correlated with the dose of vaccine received ( r = 0.53, p = 0.004). Beekeeping (RR = 29.54, p venom allergy. Venom immunotherapy is highly efficacious and safe as most of the adverse events during the induction and maintenance phase are mild and local. Side effects of VIT are more common in subjects on bee VIT. Beekeeping and female sex are associated with a higher risk of allergy to Hymenoptera venom.

  4. Exploring sustainability transitions in households: insights from real-life experiments

    Science.gov (United States)

    Baedeker, Carolin; Buhl, Johannes; Greiff, Kathrin; Hasselkuß, Marco; Liedtke, Christa; Lukas, Melanie

    2016-04-01

    Societal transformation towards sustainable consumption and production, especially in urban areas, is a key challenge. The design and implementation of sustainable product service systems (PSS) might be the initial point, in which private households play a major role. The Sustainable LivingLab research infrastructure was developed as an experimental setting for investigating consumption and production patterns in private households, especially to explore socio-technical innovations which are helpful to guide sustainability transitions. The suggested presentation describes results of several real-life experiments conducted in German households, e.g. the project SusLabNRW (North-Rhine Westphalia as part of the European SusLabNWE-Project), the EnerTransRuhr project as well as the PATHWAYS project that explore patterns of action, time use, social practices and the related resource use in private households. The presentation gives an overview of the employed methods and analysed data (qualitative interviews, social network analysis, survey on household activities and inventories and a sustainability assessment (resource profiles - MIPS household analysis). Households' resource consumption was calculated in all fields of activity to analyse social practices' impact. The presentation illustrates how aggregated data can inform scenario analysis and concludes with an outlook onto transition pathways at household level and socio-technical innovations in the fields of housing, nutrition and mobility.

  5. Real Heroes.

    Science.gov (United States)

    Denenberg, Dennis

    2001-01-01

    Presents stories taken from the book, "50 American Heroes Every Kid Should Meet," explaining that children need to learn about the value of real-life human accomplishments (versus those of athletes, television personalities, and rock stars). The heroes include Elizabeth Blackwell, first American woman doctor; George C. Marshall,…

  6. Numerical solution of system of boundary value problems using B-spline with free parameter

    Science.gov (United States)

    Gupta, Yogesh

    2017-01-01

    This paper deals with method of B-spline solution for a system of boundary value problems. The differential equations are useful in various fields of science and engineering. Some interesting real life problems involve more than one unknown function. These result in system of simultaneous differential equations. Such systems have been applied to many problems in mathematics, physics, engineering etc. In present paper, B-spline and B-spline with free parameter methods for the solution of a linear system of second-order boundary value problems are presented. The methods utilize the values of cubic B-spline and its derivatives at nodal points together with the equations of the given system and boundary conditions, ensuing into the linear matrix equation.

  7. Motivational valence alters memory formation without altering exploration of a real-life spatial environment

    Science.gov (United States)

    Hashemi, Jordan; Gans, Lee K.; Lerebours, Laura; Clement, Nathaniel J.; Vu, Mai-Anh T.; Sapiro, Guillermo; Heller, Nicole E.; Adcock, R. Alison

    2018-01-01

    motivated learning implies that dissociable behavioral and biological mechanisms, here varying as a function of valence, contribute to memory outcomes in complex, real-life environments. PMID:29558526

  8. Motivational valence alters memory formation without altering exploration of a real-life spatial environment.

    Directory of Open Access Journals (Sweden)

    Kimberly S Chiew

    characterization of motivated learning implies that dissociable behavioral and biological mechanisms, here varying as a function of valence, contribute to memory outcomes in complex, real-life environments.

  9. Motivational valence alters memory formation without altering exploration of a real-life spatial environment.

    Science.gov (United States)

    Chiew, Kimberly S; Hashemi, Jordan; Gans, Lee K; Lerebours, Laura; Clement, Nathaniel J; Vu, Mai-Anh T; Sapiro, Guillermo; Heller, Nicole E; Adcock, R Alison

    2018-01-01

    motivated learning implies that dissociable behavioral and biological mechanisms, here varying as a function of valence, contribute to memory outcomes in complex, real-life environments.

  10. The Effectiveness of Life Skills Training on the MotherـChild Relationship in Mothers of Children with Hearing Problems

    Directory of Open Access Journals (Sweden)

    خلیل کاکاوندی

    2017-01-01

    Full Text Available The purpose of present study was to investigate the effect of life skills training on the mother-child relationship in mothers of children with hearing problems. The study’s procedure was experimental with pretest-posttest design employing a control group. The participants include 36 mothers of children with hearing problems in Shiraz who were selected by an available sampling method and assigned into experimental and control group, randomly; hence, each group included 18 mothers. Both groups had undergone a pre-test. The experimental group received life skills training in 12 sessions while the control group did not. After the intervention period the post-test was administered for both groups. The Roth mother-child relationship strategies scale (1961 was employed to assess the mother-child relationship strategies. The data analyses by ANCOVA showed that there was a significant effect in the mean score of mother-child relationship in mothers of children with hearing problems in the experimental group (p<0/0001 and increased the acceptance of child and reduced the overprotection, the overindulgence and the child rejection among the mothers of experimental group. Therefore, life skills training program construction and employment are highly recommendable to improve mother-child relationship strategies among mothers of children with hearing problems.

  11. Health-related quality of life, cognitive functioning and behaviour problems in children with Langerhans cell histiocytosis

    NARCIS (Netherlands)

    Vrijmoet-Wiersma, C. M. Jantien; Kooloos, Vicky M.; Koopman, Hendrik M.; Kolk, Annemarie M.; van der Laan, Ingrid; Grootenhuis, Martha A.; Egeler, R. Maarten

    2009-01-01

    BACKGROUND: This study was designed to evaluate generic and disease-specific health-related quality of life (HRQoL), cognitive functioning and behaviour problems of children with Langerhans Cell Histiocytosis (LCH). Furthermore, we investigated which medical determinants and social demographic

  12. 'Real-life' effectiveness studies of omalizumab in adult patients with severe allergic asthma: systematic review.

    Science.gov (United States)

    Abraham, I; Alhossan, A; Lee, C S; Kutbi, H; MacDonald, K

    2016-05-01

    We reviewed 24 'real-life' effectiveness studies of omalizumab in the treatment of severe allergic asthma that included 4117 unique patients from 32 countries with significant heterogeneity in patients, clinicians and settings. The evidence underscores the short- and long-term benefit of anti-IgE therapy in terms of the following: improving lung function; achieving asthma control and reducing symptomatology, severe exacerbations and associated work/school days lost; reducing healthcare resource utilizations, in particular hospitalizations, hospital lengths of stay and accident specialist or emergency department visits; reducing or discontinuing other asthma medications; and improving quality of life - thus confirming, complementing and extending evidence from randomized trials. Thus, omalizumab therapy is associated with signal improvements across the full objective and subjective burden of illness chain of severe allergic asthma. Benefits of omalizumab may extend up to 2-4 years, and the majority of omalizumab-treated patients may benefit for many years. Omalizumab has positive short- and long-term safety profiles similar to what is known from randomized clinical trials. Initiated patients should be monitored for treatment response at 16 weeks. Those showing positive response at that time are highly likely to show sustained treatment response and benefit in terms of clinical, quality of life and health resource utilization outcomes. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. PROBLEM PENDIDIKAN VIDEO GAMES DALAM PERSPEKTIF TEORI SIMULACRA JEAN BAUDRILLARD

    OpenAIRE

    Siti Murtiningsih, Joko Siswanto, M. Mukhtasar Syamsudin

    2013-01-01

    Abstract: Education Problems of Video Games in the Perspective of Jean Baudrillard’s Theory of Simulacra. In the era of digital age, we are witnessing how video games penetrate children’s daily life and it is believed to have some impacts on their cognitive and affective processes. Referring to hermeneutical approach, the present library research seeks to answer the question whether video games create a real identity or simply forge false consciousness in children. In the first step, the data...

  14. Off the fence, onto the bandwagon? A large-scale survey experiment on effect of real-life poll outcomes on subsequent vote intentions

    NARCIS (Netherlands)

    van der Meer, T.W.G.; Hakhverdian, A.; Aaldering, L.

    2016-01-01

    Despite decades of scholarly inquiry, the debate on the existence of a bandwagon effect in politics remains undecided. This article aims to overcome the limitations of previous experimental and survey research. We test to what extent success in real-life polling outcomes of the previous weeks

  15. A Hybrid ACO Approach to the Matrix Bandwidth Minimization Problem

    Science.gov (United States)

    Pintea, Camelia-M.; Crişan, Gloria-Cerasela; Chira, Camelia

    The evolution of the human society raises more and more difficult endeavors. For some of the real-life problems, the computing time-restriction enhances their complexity. The Matrix Bandwidth Minimization Problem (MBMP) seeks for a simultaneous permutation of the rows and the columns of a square matrix in order to keep its nonzero entries close to the main diagonal. The MBMP is a highly investigated {NP}-complete problem, as it has broad applications in industry, logistics, artificial intelligence or information recovery. This paper describes a new attempt to use the Ant Colony Optimization framework in tackling MBMP. The introduced model is based on the hybridization of the Ant Colony System technique with new local search mechanisms. Computational experiments confirm a good performance of the proposed algorithm for the considered set of MBMP instances.

  16. Cybersex addiction: Experienced sexual arousal when watching pornography and not real-life sexual contacts makes the difference.

    Science.gov (United States)

    Laier, Christian; Pawlikowski, Mirko; Pekal, Jaro; Schulte, Frank P; Brand, Matthias

    2013-06-01

    Background and aims Cybersex addiction is discussed controversially, while empirical evidence is widely missing. With respect to its mechanisms of development and maintenance Brand et al. (2011) assume that reinforcement due to cybersex should lead to the development of cue-reactivity and craving explaining recurrent cybersex use in the face of growing but neglected negative consequences. To support this hypothesis, two experimental studies were conducted. Methods In a cue-reactivity paradigm 100 pornographic cues were presented to participants and indicators of sexual arousal and craving were assessed. The first study aimed at identifying predictors of cybersex addiction in a freely recruited sample of 171 heterosexual males. The aim of the second study was to verify the findings of the first study by comparing healthy (n = 25) and problematic (n = 25) cybersex users. Results The results show that indicators of sexual arousal and craving to Internet pornographic cues predicted tendencies towards cybersex addiction in the first study. Moreover, it was shown that problematic cybersex users report greater sexual arousal and craving reactions resulting from pornographic cue presentation. In both studies, the number and subjective quality of real-life sexual contacts were not associated to cybersex addiction. Discussion The results support the gratification hypothesis, which assumes reinforcement, learning mechanisms, and craving to be relevant processes in the development and maintenance of cybersex addiction. Poor or unsatisfying sexual real-life contacts cannot sufficiently explain cybersex addiction. Conclusions Positive reinforcement in terms of gratification plays a major role in cybersex addiction.

  17. A Life Course Model of Self-Reported Violence Exposure and Ill-health with A Public Health Problem Perspective.

    Science.gov (United States)

    Olofsson, Niclas

    2014-01-01

    Violence has probably always been part of the human experience. Its impact can be seen, in various forms, in all parts of the world. In 1996, WHO:s Forty-Ninth World Health Assembly adopted a resolution, declaring violence a major and growing public health problem around the world. Public health work centers around health promotion and disease prevention activities in the population and public health is an expression of the health status of the population taking into account both the level and the distribution of health. Exposure to violence can have many aspects, differing throughout the life course - deprivation of autonomy, financial exploitation, psychological and physical neglect or abuse - but all types share common characteristics: the use of destructive force to control others by depriving them of safety, freedom, health and, in too many instances, life; the epidemic proportions of the problem, particularly among vulnerable groups; a devastating impact on individuals, families, neighborhoods, communities, and society. There is considerable evidence that stressful early life events influence a variety of physical and/or psychological health problems later in life. Childhood adversity has been linked to elevated rates of morbidity and mortality from number of chronic diseases. A model outlining potential biobehavioural pathways is put forward that may be a potential explanation of how exposure to violence among both men and women work as an important risk factor for ill health and should receive greater attention in public health work.

  18. Towards real energy economics: Energy policy driven by life-cycle carbon emission

    International Nuclear Information System (INIS)

    Kenny, R.; Law, C.; Pearce, J.M.

    2010-01-01

    Alternative energy technologies (AETs) have emerged as a solution to the challenge of simultaneously meeting rising electricity demand while reducing carbon emissions. However, as all AETs are responsible for some greenhouse gas (GHG) emissions during their construction, carbon emission 'Ponzi Schemes' are currently possible, wherein an AET industry expands so quickly that the GHG emissions prevented by a given technology are negated to fabricate the next wave of AET deployment. In an era where there are physical constraints to the GHG emissions the climate can sustain in the short term this may be unacceptable. To provide quantitative solutions to this problem, this paper introduces the concept of dynamic carbon life-cycle analyses, which generate carbon-neutral growth rates. These conceptual tools become increasingly important as the world transitions to a low-carbon economy by reducing fossil fuel combustion. In choosing this method of evaluation it was possible to focus uniquely on reducing carbon emissions to the recommended levels by outlining the most carbon-effective approach to climate change mitigation. The results of using dynamic life-cycle analysis provide policy makers with standardized information that will drive the optimization of electricity generation for effective climate change mitigation.

  19. A life course perspective on mental health problems, employment, and work outcomes.

    Science.gov (United States)

    Veldman, Karin; Reijneveld, Sijmen A; Verhulst, Frank C; Ortiz, Josue Almansa; Bültmann, Ute

    2017-07-01

    Objectives Little is known about how employment and work outcomes among young adults are influenced by their life-course history of mental health problems. Therefore, the aims of this study were to (i) identify trajectories of mental health problems from childhood to young adulthood and (ii) investigate the association between these trajectories and employment and work outcomes among young adults. Methods Data were used from 360 participants of the Tracking Adolescents' Individual Lives Survey (TRAILS), a Dutch prospective cohort study, with 12-year follow-up. Trajectories of externalizing and internalizing problems were identified with latent class growth models. Employment conditions and work outcomes (ie, psychosocial work characteristics) were measured at age 22. We assessed the association between mental health trajectories and employment conditions and work outcomes. Results Four trajectories of mental health problems were identified: high-stable, decreasing, moderate-stable and low-stable. Young adults with high-stable trajectories of externalizing problems worked over six hours more [B=6.71, 95% confidence interval (95% CI) 2.82-10.6] and had a higher income [odds ratio (OR) 0.33, 95% CI 0.15-0.71], than young adults with low-stable trajectories. Young adults with high-stable trajectories of internalizing problems worked six hours less per week (B=-6.07, 95% CI -10.1- -2.05) and reported lower income (OR 3.44, 95% CI 1.53-7.74) and poorer psychosocial work characteristics, compared to young adults with low-stable trajectories. Conclusions Among young adults who had a paid job at the age of 22 (and were not a student or unemployed), those with a history of internalizing problems are less likely to transition successfully into the labor market, compared to other young adults.

  20. The Italian compassionate use of sofosbuvir in HCV patients waitlisted for liver transplantation: A national real-life experience.

    Science.gov (United States)

    Martini, Silvia; Donato, Maria Francesca; Mazzarelli, Chiara; Rendina, Maria; Visco-Comandini, Ubaldo; Filì, Daniela; Gianstefani, Alice; Fagiuoli, Stefano; Melazzini, Mario; Montilla, Simona; Pani, Luca; Petraglia, Sandra; Russo, Pierluigi; Trotta, Maria Paola; Carrai, Paola; Caraceni, Paolo

    2018-04-01

    This study aimed to assess the real-life clinical and virological outcomes of HCV waitlisted patients for liver transplantation (LT) who received sofosbuvir/ribavirin (SOF/R) within the Italian compassionate use program. Clinical and virological data were collected in 224 patients with decompensated cirrhosis and/or hepatocellular carcinoma (HCC) receiving daily SOF/R until LT or up a maximum of 48 weeks. Of 100 transplanted patients, 51 were HCV-RNA negative for >4 weeks before LT (SVR12: 88%) and 49 negative for <4 weeks or still viraemic at transplant: 34 patients continued treatment after LT (bridging therapy) (SVR12: 88%), while 15 stopped treatment (SVR12: 53%). 98 patients completed SOF/R without LT (SVR12: 73%). In patients with advanced decompensated cirrhosis (basal MELD ≥15 and/or C-P ≥B8), a marked improvement of the scores occurred in about 50% of cases and almost 20% of decompensated patients without HCC reached a condition suitable for inactivation and delisting. These real-life data indicate that in waitlisted patients: (i) bridging antiviral therapy can be an option for patients still viraemic or negative <4 weeks at LT; and (ii) clinical improvement to a condition suitable for delisting can occur even in patients with advanced decompensated cirrhosis. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Numerical simulation of real-world flows

    Energy Technology Data Exchange (ETDEWEB)

    Hayase, Toshiyuki, E-mail: hayase@ifs.tohoku.ac.jp [Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, 980-8577 (Japan)

    2015-10-15

    Obtaining real flow information is important in various fields, but is a difficult issue because measurement data are usually limited in time and space, and computational results usually do not represent the exact state of real flows. Problems inherent in the realization of numerical simulation of real-world flows include the difficulty in representing exact initial and boundary conditions and the difficulty in representing unstable flow characteristics. This article reviews studies dealing with these problems. First, an overview of basic flow measurement methodologies and measurement data interpolation/approximation techniques is presented. Then, studies on methods of integrating numerical simulation and measurement, namely, four-dimensional variational data assimilation (4D-Var), Kalman filters (KFs), state observers, etc are discussed. The first problem is properly solved by these integration methodologies. The second problem can be partially solved with 4D-Var in which only initial and boundary conditions are control parameters. If an appropriate control parameter capable of modifying the dynamical structure of the model is included in the formulation of 4D-Var, unstable modes are properly suppressed and the second problem is solved. The state observer and KFs also solve the second problem by modifying mathematical models to stabilize the unstable modes of the original dynamical system by applying feedback signals. These integration methodologies are now applied in simulation of real-world flows in a wide variety of research fields. Examples are presented for basic fluid dynamics and applications in meteorology, aerospace, medicine, etc. (topical review)

  2. Managing Inflections in Life and Career: Tale from a Physicist

    Science.gov (United States)

    Bhattacharya, Santanu

    2010-03-01

    By training, a physicist possesses one of the rarest qualities ever imparted in an educational degree program, namely, the ability to take on complex problems, divide them into ``solvable'' parts, derive solutions and put them back as insightful outputs. Dr Bhattacharya, CEO of Salorix, a research, analytics and consulting firm, explains how he has used these skills learned at the graduate school to build a career as a scientist, management consultant and entrepreneur. He will also speak about how the real-life skillsets of understanding and dealing with ``Inflections'', self discovery and introspection can be a great tool for managing one's life and career progression.

  3. Prototyping real-time systems

    OpenAIRE

    Clynch, Gary

    1994-01-01

    The traditional software development paradigm, the waterfall life cycle model, is defective when used for developing real-time systems. This thesis puts forward an executable prototyping approach for the development of real-time systems. A prototyping system is proposed which uses ESML (Extended Systems Modelling Language) as a prototype specification language. The prototyping system advocates the translation of non-executable ESML specifications into executable LOOPN (Language of Object ...

  4. Severe interpersonal violence against children in sport: Associated mental health problems and quality of life in adulthood.

    Science.gov (United States)

    Vertommen, Tine; Kampen, Jarl; Schipper-van Veldhoven, Nicolette; Uzieblo, Kasia; Van Den Eede, Filip

    2018-02-01

    In a recent large-scale prevalence study of interpersonal violence (IV) against child athletes in the Netherlands and Belgium we found that 9% of adult respondents who participated in organized sports before the age of 18 had experienced severe psychological violence, 8% severe physical violence, and 6% severe sexual violence in various sport settings. While the general literature has repeatedly shown that exposure to IV during childhood is associated with mental health problems in adulthood and to a lesser extent with reduced quality of life (QOL), these relationships have not been demonstrated in (former) athletes. Thus, the current study aims to assess the association of severe childhood IV in sport and adult wellbeing. Depression, anxiety, and somatization were assessed in the same general population sample (N = 4043) using the Brief Symptom Inventory (BSI-18) and QOL with the World Health Organization Quality of Life questionnaire (WHOQOL-Brèf). The association between severe IV in sport and adult wellbeing was investigated using multiple linear regression while controlling for demographics, recent life events, and relatives' psychological problems. We found severe sexual, physical, and psychological childhood IV in sport to be associated with more adult psychological distress and reduced QOL. Polyvictimization shows the strongest correlation with poorer wellbeing and QOL. Recent life events, relatives' psychological problems, marital status, and level of education were significant covariates in the psychological symptoms and QOL assessed. We hope that these new insights prompt sport administrators to implement broad spectrum child protection measures and raise the awareness of mental health professionals about the necessity to also screen for adverse childhood experiences in the sport context. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Adverse life events as risk factors for behavioural and emotional problems in a 7-year follow-up of a population-based child cohort.

    Science.gov (United States)

    Rasmussen, Cathrine Skovmand; Nielsen, Louise Gramstrup; Petersen, Dorthe Janne; Christiansen, Erik; Bilenberg, Niels

    2014-04-01

    The aim of the study was to identify risk factors for significant changes in emotional and behavioural problem load in a community-based cohort of Danish children aged 9-16 years, the risk factors being seven parental and two child-related adverse life events. Data on emotional and behavioural problems was obtained from parents filling in the Child Behavior Checklist (CBCL) when the child was 8-9 and again when 15 years old. Data on risk factors was drawn from Danish registers. Analysis used was logistic regression for crude and adjusted change. Parental divorce significantly raised the odds ratio of an increase in emotional and behavioural problems; furthermore, the risk of deterioration in problem behaviour rose significantly with increasing number of adverse life events. By dividing the children into four groups based on the pathway in problem load (increasers, decreasers, high persisters and low persisters), we found that children with a consistently high level of behavioural problems also had the highest number of adverse life events compared with any other group. Family break-up was found to be a significant risk factor. This supports findings in previous studies. The fact that no other risk factor proved to be of significance might be due to lack of power in the study. Children experiencing high levels of adverse life events are at high risk of chronic problem behaviour. Thus these risk factors should be assessed in daily clinical practice.

  6. Who Am I? A Life Story Intervention for Persons with Intellectual Disability and Psychiatric Problems

    Science.gov (United States)

    Westerhof, Gerben J.; Beernink, Janny; Sools, Anneke

    2016-01-01

    This article describes an innovative intervention based on narrative and life review therapy that is tailored to people with intellectual disability (ID) and psychiatric problems. The current study provides a first evaluation of the intervention. A symptom checklist (SCL-90) was used in a pre- and post-follow-up design, and a qualitative…

  7. Assessing acupuncture effect in the real world study

    Directory of Open Access Journals (Sweden)

    Qi-Wen Zhang

    2017-04-01

    Full Text Available Acupuncture, with its unique set of theories and its evident results in clinical practice is an important part of traditional Chinese medicine (TCM, and gaining recognition worldwide for the past few years. Although acupuncture treatment is generally accepted by the public, a few western researchers believe that sufficient evidence of its efficiency is still currently lacking, therefore creating a challenge of its acceptance on a wider scale. This article suggests the concepts of acupuncture behind clinical researches by reviewing the clinical researches done, analyzing the existing problems, and integrating real life acupuncture into the research process. By increasing the credibility of acupuncture, its reach can be extended globally and to more countries and regions.

  8. Comparison of cortical activation during Mahjong game play in a video game setting and a real-life setting

    OpenAIRE

    Fujimori, Satomi; Terasawa, Koji; Murata, Yuki; Ogawa, Kishiko; Tabuchi, Hisaaki; Yanagisawa, Hiroki; Terasawa, Saiki; Shinohara, Kikunori; Yanagisawa, Akitaka

    2015-01-01

    The purpose of this study was to compare the hemodynamic changes that occur during Mahjong game play in virtual and real-life settings. Fourteen healthy right-handed men (average age ± standard deviation; 36.7 ± 14.9 years) played: 1) a Mahjong solitaire game on a video console against virtual rivals; 2) a Mahjong game against human opponents without conversation; and 3) a Mahjong game against human opponents with conversation. We measured oxygenated hemoglobin concentration at 44 locations o...

  9. A duality approach for solving bounded linear programming problems with fuzzy variables based on ranking functions and its application in bounded transportation problems

    Science.gov (United States)

    Ebrahimnejad, Ali

    2015-08-01

    There are several methods, in the literature, for solving fuzzy variable linear programming problems (fuzzy linear programming in which the right-hand-side vectors and decision variables are represented by trapezoidal fuzzy numbers). In this paper, the shortcomings of some existing methods are pointed out and to overcome these shortcomings a new method based on the bounded dual simplex method is proposed to determine the fuzzy optimal solution of that kind of fuzzy variable linear programming problems in which some or all variables are restricted to lie within lower and upper bounds. To illustrate the proposed method, an application example is solved and the obtained results are given. The advantages of the proposed method over existing methods are discussed. Also, one application of this algorithm in solving bounded transportation problems with fuzzy supplies and demands is dealt with. The proposed method is easy to understand and to apply for determining the fuzzy optimal solution of bounded fuzzy variable linear programming problems occurring in real-life situations.

  10. Older adults' alcohol consumption and late-life drinking problems: a 20-year perspective.

    Science.gov (United States)

    Moos, Rudolf H; Schutte, Kathleen K; Brennan, Penny L; Moos, Bernice S

    2009-08-01

    The aim of this study was to identify changes in patterns of alcohol consumption over a 20-year interval among older women and men, and to examine the associations between guideline-defined excessive drinking and late-life drinking problems. DESIGN, PARTICIPANTS AND MEASURES: A community sample of 719 adults between 55 and 65 years of age who consumed alcohol at or prior to baseline participated in a survey of alcohol consumption and drinking problems and was followed 10 years and 20 years later. The likelihood of excessive drinking declined over the 20-year interval as adults matured into their 70s and 80s. However, at ages 75-85, 27.1% of women and 48.6% of men consumed more than two drinks per day or seven drinks per week. At comparable guideline levels of alcohol consumption, older men were more likely to have drinking problems than were older women. Consumption of more than two drinks per day or seven drinks per week was identified as a potential conservative guideline for identifying excessive drinking associated with an elevated likelihood of drinking problems. A substantial percentage of older adults who consume alcohol engage in guideline-defined excessive drinking and incur drinking problems. The finding that older men may be more likely than older women to experience problems when they drink beyond guideline levels suggests that alcohol guidelines for men should not be set higher than those for women.

  11. Older Adults’ Alcohol Consumption and Late-Life Drinking Problems: A 20-Year Perspective

    Science.gov (United States)

    Moos, Rudolf H.; Schutte, Kathleen K.; Brennan, Penny L.; Moos, Bernice S.

    2009-01-01

    Aims The aim was to identify changes in patterns of alcohol consumption over a 20-year interval among older women and men, and to examine the associations between guideline-defined excessive drinking and late-life drinking problems. Design, Participants, and Measures A community sample of 719 adults between 55 and 65 years of age who consumed alcohol at or prior to baseline participated in a survey of alcohol consumption and drinking problems and was followed 10 years and 20 years later. Findings The likelihood of excessive drinking declined over the 20-year interval as adults matured into their 70s and 80s. However, at ages 75–85, 27% of women and 49% of men consumed more than 2 drinks per day or 7 drinks per week. At comparable guideline levels of alcohol consumption, older men were more likely to have drinking problems than were older women. Consumption of more than 2 drinks per day or 7 drinks per week was identified as a potential conservative guideline for identifying excessive drinking associated with an elevated likelihood of drinking problems. Conclusions A substantial percentage of older adults who consume alcohol engage in guideline-defined excessive drinking and incur drinking problems. The finding that older men may be more likely than older women to experience problems when they drink beyond guideline levels suggests that alcohol guidelines for men should not be set higher than those for women. PMID:19438836

  12. Life Stressors as Mediators of the Relation Between Socioeconomic Position and Mental Health Problems in Early Adolescence : The TRAILS Study

    NARCIS (Netherlands)

    Amone-P'Olak, K.; Ormel, J.; Huisman, Martijn; Verhulst, F.C.; Oldehinkel, A.J.; Burger, Huib

    2009-01-01

    Objective: Life stressors and family socioeconomic position have often been associated with mental health status. The aim of the present study is to contribute to the understanding of the pathways from low socioeconomic position and life stressors to mental problems. Method: In a cross-sectional

  13. Students' satisfaction to hybrid problem-based learning format for basic life support/advanced cardiac life support teaching.

    Science.gov (United States)

    Chilkoti, Geetanjali; Mohta, Medha; Wadhwa, Rachna; Saxena, Ashok Kumar; Sharma, Chhavi Sarabpreet; Shankar, Neelima

    2016-11-01

    Students are exposed to basic life support (BLS) and advanced cardiac life support (ACLS) training in the first semester in some medical colleges. The aim of this study was to compare students' satisfaction between lecture-based traditional method and hybrid problem-based learning (PBL) in BLS/ACLS teaching to undergraduate medical students. We conducted a questionnaire-based, cross-sectional survey among 118 1 st -year medical students from a university medical college in the city of New Delhi, India. We aimed to assess the students' satisfaction between lecture-based and hybrid-PBL method in BLS/ACLS teaching. Likert 5-point scale was used to assess students' satisfaction levels between the two teaching methods. Data were collected and scores regarding the students' satisfaction levels between these two teaching methods were analysed using a two-sided paired t -test. Most students preferred hybrid-PBL format over traditional lecture-based method in the following four aspects; learning and understanding, interest and motivation, training of personal abilities and being confident and satisfied with the teaching method ( P < 0.05). Implementation of hybrid-PBL format along with the lecture-based method in BLS/ACLS teaching provided high satisfaction among undergraduate medical students.

  14. An Analyses and Solution Proposals Toward Social Gender Equality Problems in Business Life at Work Place in Turkey

    OpenAIRE

    Ayse Kocabacak; Cumali Kalkan

    2015-01-01

    Gender inequality is a problem in the World as well as in Turkey. What is referred by this problem here is the gender discrimination and thus inequality and injustice in opportunities that women face in a society. It appears in different forms in business life or at work place (inequalities in employment, wages, social benefits and education as well as obstacles in career rise, easy dismissal or layoff, sexual harassment / persecution / mobbing, etc.). In this study, this problem is investiga...

  15. Physiologically based pharmacokinetic toolkit to evaluate environmental exposures: Applications of the dioxin model to study real life exposures

    Energy Technology Data Exchange (ETDEWEB)

    Emond, Claude, E-mail: claude.emond@biosmc.com [BioSimulation Consulting Inc, Newark, DE (United States); Ruiz, Patricia; Mumtaz, Moiz [Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States)

    2017-01-15

    Chlorinated dibenzo-p-dioxins (CDDs) are a series of mono- to octa-chlorinated homologous chemicals commonly referred to as polychlorinated dioxins. One of the most potent, well-known, and persistent member of this family is 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). As part of translational research to make computerized models accessible to health risk assessors, we present a Berkeley Madonna recoded version of the human physiologically based pharmacokinetic (PBPK) model used by the U.S. Environmental Protection Agency (EPA) in the recent dioxin assessment. This model incorporates CYP1A2 induction, which is an important metabolic vector that drives dioxin distribution in the human body, and it uses a variable elimination half-life that is body burden dependent. To evaluate the model accuracy, the recoded model predictions were compared with those of the original published model. The simulations performed with the recoded model matched well with those of the original model. The recoded model was then applied to available data sets of real life exposure studies. The recoded model can describe acute and chronic exposures and can be useful for interpreting human biomonitoring data as part of an overall dioxin and/or dioxin-like compounds risk assessment. - Highlights: • The best available dioxin PBPK model for interpreting human biomonitoring data is presented. • The original PBPK model was recoded from acslX to the Berkeley Madonna (BM) platform. • Comparisons were made of the accuracy of the recoded model with the original model. • The model is a useful addition to the ATSDR's BM based PBPK toolkit that supports risk assessors. • The application of the model to real-life exposure data sets is illustrated.

  16. A nationwide study of health-related quality of life, stress, pain or discomfort and the use of medicine among problem gamblers

    DEFF Research Database (Denmark)

    Ekholm, Ola; Davidsen, Michael; Larsen, Christina Viskum Lytken

    2018-01-01

    AIM: The aim of this study was to investigate the associations between problem gambling and health-related quality of life, stress, pain or discomfort and the use of analgesics and sleeping pills. METHODS: Data derives from the Danish Health and Morbidity Survey 2010. The survey was based......, high perception of stress, headache, fatigue and sleeping problems. Furthermore, previous problem gambling was generally associated with poorer health outcomes. Thus, current and previous problem gamblers had 2.36 times (95% confidence interval [CI] 1.44-3.87) and 1.66 times (95% CI 1.07-2.55) higher...... included topics such as health-related quality of life (Short Form-12), perceived stress, pain and discomforts within the past two weeks, as well as the use of medication within the past two weeks. RESULTS: Current problem gambling was strongly associated with negative outcomes such as poor mental health...

  17. The Impact of Life Skills Training on Behavior Problems in Left-Behind Children in Rural China: A Pilot Study

    Science.gov (United States)

    Liu, Jia; Liu, Shan; Yan, Jin; Lee, Elizabeth; Mayes, Linda

    2016-01-01

    A randomized controlled experimental pilot study was conducted in order to investigate the effect of life skills training on behavior problems in left-behind children (LBC) in rural China. Sixty-eight LBC were recruited from a middle school in rural China. The intervention group took a ten-week-long life skills training course. The Child Behavior…

  18. Y2K issues for real time computer systems for fast breeder test reactor

    International Nuclear Information System (INIS)

    Swaminathan, P.

    1999-01-01

    Presentation shows the classification of real time systems related to operation, control and monitoring of the fast breeder test reactor. Software life cycle includes software requirement specification, software design description, coding, commissioning, operation and management. A software scheme in supervisory computer of fast breeder test rector is described with the twenty years of experience in design, development, installation, commissioning, operation and maintenance of computer based supervision control system for nuclear installation with a particular emphasis on solving the Y2K problem

  19. A Novel Computational Tool for Mining Real-Life Data: Application in the Metastatic Colorectal Cancer Care Setting.

    Science.gov (United States)

    Siegelmann-Danieli, Nava; Farkash, Ariel; Katzir, Itzhak; Vesterman Landes, Janet; Rotem Rabinovich, Hadas; Lomnicky, Yossef; Carmeli, Boaz; Parush-Shear-Yashuv, Naama

    2016-01-01

    Randomized clinical trials constitute the gold-standard for evaluating new anti-cancer therapies; however, real-life data are key in complementing clinically useful information. We developed a computational tool for real-life data analysis and applied it to the metastatic colorectal cancer (mCRC) setting. This tool addressed the impact of oncology/non-oncology parameters on treatment patterns and clinical outcomes. The developed tool enables extraction of any computerized information including comorbidities and use of drugs (oncological/non-oncological) per individual HMO member. The study in which we evaluated this tool was a retrospective cohort study that included Maccabi Healthcare Services members with mCRC receiving bevacizumab with fluoropyrimidines (FP), FP plus oxaliplatin (FP-O), or FP plus irinotecan (FP-I) in the first-line between 9/2006 and 12/2013. The analysis included 753 patients of whom 15.4% underwent subsequent metastasectomy (the Surgery group). For the entire cohort, median overall survival (OS) was 20.5 months; in the Surgery group, median duration of bevacizumab-containing therapy (DOT) pre-surgery was 6.1 months; median OS was not reached. In the Non-surgery group, median OS and DOT were 18.7 and 11.4 months, respectively; no significant OS differences were noted between FP-O and FP-I, whereas FP use was associated with shorter OS (12.3 month; p controlling for age and gender) identified several non-oncology parameters associated with poorer clinical outcomes including concurrent use of diuretics and proton-pump inhibitors. Our tool provided insights that confirmed/complemented information gained from randomized-clinical trials. Prospective tool implementation is warranted.

  20. Exploring and modelling impacts of third molar experience on quality of life: a real-time qualitative study using Twitter.

    Science.gov (United States)

    Hanna, Kamal; Sambrook, Paul; Armfield, Jason M; Brennan, David S

    2017-10-01

    This study had two objectives: (i) to explore and model domains describing the real-time impact of third molars (TMs) on quality of life (QoL); and (ii) to assess the percentage coverage, in some generic health-related quality of life (HRQoL) and oral health-related quality of life (OHRQoL) instruments, of the TM QoL domains identified in this study. A global cross-sectional sample of tweets containing 'wisdom tooth' over a 1-week period retrieved 3,537 tweets. After random quota sampling, classification and filtering, only 843 tweets were included in the thematic analysis. A TM QoL model was constructed based on the associations of the identified domains. Domains for the selected generic HRQoL and OHRQoL instruments were plotted against the domains identified in the study to calculate the percentage coverage for each. The QoL domains identified were pain (n = 348, 41%), mood (n = 173, 20%), anxiety and fear (n = 54, 7%), enjoying food (n = 41, 4%), coping (n = 37, 4%), daily activities (n = 34, 4%), sleep (n = 24, 2%), social life (n = 19, 2%), physical health (n = 17, 2%), ability to think (n = 9, 1%), self-care (n = 8, 1%) and sporting & recreation (n = 2, <1%). The Assessment Quality of Life instrument (AQoL-8D) covers 87% of the TM QoL domains, while the rest of the HRQoL and OHRQoL instruments cover 33-60%. This study shows how Twitter can be used to obtain real-time QoL data, which might be used to model how TMs impact on QoL. The TM QoL domains identified in the study were generally under-represented among the generic OHRQoL instruments assessed while, the HRQoL AQoL-8D covered most of the TM QoL domains. The QoL domains identified in the study might be used to develop a new OHRQoL measure for TMs. © 2017 FDI World Dental Federation.

  1. Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human leukemia CCRF-CEM and Nalm-6 cell lines

    Directory of Open Access Journals (Sweden)

    Barredo Julio C

    2002-03-01

    Full Text Available Abstract Background We describe an alternative method to determine mRNA half-life (t1/2 based on the Real-Time RT-PCR procedure. This approach was evaluated by using the β-actin gene as a reference molecule for measuring of mRNA stability. Results Human leukemia Nalm-6 and CCRF-CEM cells were treated with various concentrations of Actinomycin D to block transcription and aliquots were removed periodically. Total RNA was isolated and quantified using the RiboGreen® fluorescent dye with the VersaFluor Fluorometer System. One μg of total RNA was reverse transcribed and used as template for the amplification of a region of the β-actin gene (231 bp. To generate the standard curve, serial ten-fold dilutions of the pBactin-231 vector containing the cDNA amplified fragment were employed, β-actin mRNAs were quantified by Real-Time RT-PCR using the SYBR® Green I fluorogenic dye and data analyzed using the iCycle iQ system software. Using this method, the β-actin mRNA exhibited a half-life of 6.6 h and 13.5 h in Nalm-6 and CCRF-CEM cells, respectively. The t1/2 value obtained for Nalm-6 is comparable to those estimated from Northern blot studies, using normal human leukocytes (5.5 h. Conclusions We have developed a rapid, sensitive, and reliable method based on Real-Time RT-PCR for measuring mRNA half-life. Our results confirm that β-actin mRNA half-life can be affected by the cellular growth rate.

  2. The real limits to marine life: a further critique of the Respiration Index

    Science.gov (United States)

    Seibel, B. A.; Childress, J. J.

    2013-05-01

    The recently proposed "Respiration Index" (RI = log PO2/PCO2) suggests that aerobic metabolism is limited by the ratio of reactants (oxygen) to products (carbon dioxide) according to the thermodynamics of cellular respiration. Here, we demonstrate further that, because of the large standard free energy change for organic carbon oxidation (ΔG° = -686 kcal mol-1), carbon dioxide can never reach concentrations that would limit the thermodynamics of this reaction. A PCO2 to PO2 ratio of 10503 would be required to reach equilibrium (equilibrium constant, Keq = 10503), where ΔG = 0. Thus, a Respiration Index of -503 would be the real thermodynamic limit to aerobic life. Such a Respiration Index is never reached, either in the cell or in the environment. Moreover, cellular respiration and oxygen provision are kinetically controlled such that, within limits, environmental oxygen and CO2 concentrations have little to do with intracellular concentrations. The RI is fundamentally different from the aragonite saturation state, a thermodynamic index used to quantify the potential effect of CO2 on calcification rates, because of its failure to incorporate the equilibrium constant of the reaction. Not only is the RI invalid, but its use leads to incorrect and misleading predictions of the threat of changing oxygen and carbon dioxide to marine life. We provide a physiological framework that identifies oxygen thresholds and allows for synergistic effects of ocean acidification and global warming.

  3. The real limits to marine life: a further critique of the Respiration Index

    Directory of Open Access Journals (Sweden)

    B. A. Seibel

    2013-05-01

    Full Text Available The recently proposed "Respiration Index" (RI = log PO2/PCO2 suggests that aerobic metabolism is limited by the ratio of reactants (oxygen to products (carbon dioxide according to the thermodynamics of cellular respiration. Here, we demonstrate further that, because of the large standard free energy change for organic carbon oxidation (ΔG° = −686 kcal mol−1, carbon dioxide can never reach concentrations that would limit the thermodynamics of this reaction. A PCO2 to PO2 ratio of 10503 would be required to reach equilibrium (equilibrium constant, Keq = 10503, where ΔG = 0. Thus, a Respiration Index of −503 would be the real thermodynamic limit to aerobic life. Such a Respiration Index is never reached, either in the cell or in the environment. Moreover, cellular respiration and oxygen provision are kinetically controlled such that, within limits, environmental oxygen and CO2 concentrations have little to do with intracellular concentrations. The RI is fundamentally different from the aragonite saturation state, a thermodynamic index used to quantify the potential effect of CO2 on calcification rates, because of its failure to incorporate the equilibrium constant of the reaction. Not only is the RI invalid, but its use leads to incorrect and misleading predictions of the threat of changing oxygen and carbon dioxide to marine life. We provide a physiological framework that identifies oxygen thresholds and allows for synergistic effects of ocean acidification and global warming.

  4. Real life narratives enhance learning about the 'art and science' of midwifery practice.

    Science.gov (United States)

    Gilkison, Andrea; Giddings, Lynne; Smythe, Liz

    2016-03-01

    Health professional educators have long grappled with how to teach the more elusive art of practice alongside the science (a term that encompasses the sort of professional knowledge that can be directly passed on). A competent practitioner is one who knows when, how and for whom to apply knowledge and skills, thereby making the links between theory and practice. They combine art and science in such a way that integrates knowledge with insight. This participatory hermeneutic study explored the experience of teachers and students of implementing a narrative-centred curriculum in undergraduate midwifery education. It revealed that when real life narratives were central to the learning environment, students' learning about the art of midwifery practice was enhanced as they learned about midwifery decisions, reflected on their own values and beliefs and felt an emotional connection with the narrator. Further, art and science became melded together in the context specific wisdom of practice (phronesis).

  5. The potential of clustering methods to define intersection test scenarios: Assessing real-life performance of AEB.

    Science.gov (United States)

    Sander, Ulrich; Lubbe, Nils

    2018-04-01

    Intersection accidents are frequent and harmful. The accident types 'straight crossing path' (SCP), 'left turn across path - oncoming direction' (LTAP/OD), and 'left-turn across path - lateral direction' (LTAP/LD) represent around 95% of all intersection accidents and one-third of all police-reported car-to-car accidents in Germany. The European New Car Assessment Program (Euro NCAP) have announced that intersection scenarios will be included in their rating from 2020; however, how these scenarios are to be tested has not been defined. This study investigates whether clustering methods can be used to identify a small number of test scenarios sufficiently representative of the accident dataset to evaluate Intersection Automated Emergency Braking (AEB). Data from the German In-Depth Accident Study (GIDAS) and the GIDAS-based Pre-Crash Matrix (PCM) from 1999 to 2016, containing 784 SCP and 453 LTAP/OD accidents, were analyzed with principal component methods to identify variables that account for the relevant total variances of the sample. Three different methods for data clustering were applied to each of the accident types, two similarity-based approaches, namely Hierarchical Clustering (HC) and Partitioning Around Medoids (PAM), and the probability-based Latent Class Clustering (LCC). The optimum number of clusters was derived for HC and PAM with the silhouette method. The PAM algorithm was both initiated with random start medoid selection and medoids from HC. For LCC, the Bayesian Information Criterion (BIC) was used to determine the optimal number of clusters. Test scenarios were defined from optimal cluster medoids weighted by their real-life representation in GIDAS. The set of variables for clustering was further varied to investigate the influence of variable type and character. We quantified how accurately each cluster variation represents real-life AEB performance using pre-crash simulations with PCM data and a generic algorithm for AEB intervention. The

  6. Interplay Among Psychopathologic Variables, Personal Resources, Context-Related Factors, and Real-life Functioning in Individuals With Schizophrenia: A Network Analysis.

    Science.gov (United States)

    Galderisi, Silvana; Rucci, Paola; Kirkpatrick, Brian; Mucci, Armida; Gibertoni, Dino; Rocca, Paola; Rossi, Alessandro; Bertolino, Alessandro; Strauss, Gregory P; Aguglia, Eugenio; Bellomo, Antonello; Murri, Martino Belvederi; Bucci, Paola; Carpiniello, Bernardo; Comparelli, Anna; Cuomo, Alessandro; De Berardis, Domenico; Dell'Osso, Liliana; Di Fabio, Fabio; Gelao, Barbara; Marchesi, Carlo; Monteleone, Palmiero; Montemagni, Cristiana; Orsenigo, Giulia; Pacitti, Francesca; Roncone, Rita; Santonastaso, Paolo; Siracusano, Alberto; Vignapiano, Annarita; Vita, Antonio; Zeppegno, Patrizia; Maj, Mario

    2018-04-01

    Enhanced understanding of factors associated with symptomatic and functional recovery is instrumental to designing personalized treatment plans for people with schizophrenia. To date, this is the first study using network analysis to investigate the associations among cognitive, psychopathologic, and psychosocial variables in a large sample of community-dwelling individuals with schizophrenia. To assess the interplay among psychopathologic variables, cognitive dysfunctions, functional capacity, personal resources, perceived stigma, and real-life functioning in individuals with schizophrenia, using a data-driven approach. This multicenter, cross-sectional study involved 26 university psychiatric clinics and/or mental health departments. A total of 921 community-dwelling individuals with a DSM-IV diagnosis of schizophrenia who were stabilized on antipsychotic treatment were recruited from those consecutively presenting to the outpatient units of the sites between March 1, 2012, and September 30, 2013. Statistical analysis was conducted between July 1 and September 30, 2017. Measures covered psychopathologic variables, neurocognition, social cognition, functional capacity, real-life functioning, resilience, perceived stigma, incentives, and service engagement. Of 740 patients (221 women and 519 men; mean [SD] age, 40.0 [10.9] years) with complete data on the 27 study measures, 163 (22.0%) were remitted (with a score of mild or better on 8 core symptoms). The network analysis showed that functional capacity and everyday life skills were the most central and highly interconnected nodes in the network. Psychopathologic variables split in 2 domains, with positive symptoms being one of the most peripheral and least connected nodes. Functional capacity bridged cognition with everyday life skills; the everyday life skills node was connected to disorganization and expressive deficits. Interpersonal relationships and work skills were connected to avolition; the interpersonal

  7. An asthma-related quality of life instrument is unable to identify asthmatic children with major psychosocial problems.

    NARCIS (Netherlands)

    Tibosch, M.M.; Reidsma, C.; Landstra, A.; Hugen, C.A.C.; Gerrits, P.; Brouwer, M.; Gent, R. van; Merkus, P.J.F.M.; Verhaak, C.M.

    2010-01-01

    Evidence shows that psychosocial problems among children and adolescents with asthma interfere with adherence to treatment and therefore need attention in asthma care. It is unknown whether the already frequently implemented asthma-related quality of life (QoL) instruments reflect psychosocial

  8. Application of a Mathematical Model to an Advertisement Reservation Problem

    Directory of Open Access Journals (Sweden)

    Ozlem COSGUN

    2013-01-01

    Full Text Available Television networks provide TV programs free of charge to the public. However, they acquire their revenue by telecasting advertisements in the midst of continuing programs or shows. A key problem faced by the TV networks in Turkey is how to accept and televise the advertisements reserved by a client on a specified advertisement break which we called “Advertisement Reservation Problem” (ARP. The problem is complicated by limited time inventory, by different rating points for different target groups, competition avoidance and the relationship between TV networks and clients. In this study we have developed a mathematical model for advertisement reservation problem and extended this model for some cases encountered in real business life. We have also discussed how these cases affect the decisions of a TV network. Mixed integer linear programming approach is proposed to solve these problems. This approach has been implemented to a case taken from one of the biggest TV networks of Turkey.

  9. Issues Involved in Developing Ada Real-Time Systems

    Science.gov (United States)

    1989-02-15

    expensive modifications to the compiler or Ada runtime system to fit a particular application. Whether we can solve the problems of programming real - time systems in...lock in solutions to problems that are not yet well understood in standards as rigorous as the Ada language. Moreover, real - time systems typically have

  10. Understanding sleep problems in children with epilepsy: Associations with quality of life, Attention-Deficit Hyperactivity Disorder and maternal emotional symptoms.

    Science.gov (United States)

    Ekinci, Ozalp; Isik, Uğur; Gunes, Serkan; Ekinci, Nuran

    2016-08-01

    This study aimed to (1) compare sleep problems between children and adolescents with epilepsy and non-epileptic controls, and (2) examine whether there is an association between sleep problems and quality of life, Attention-Deficit Hyperactivity Disorder (ADHD) and mothers' emotional symptoms. Fifty-three patients from a cohort of epilepsy (aged 7-18 years) and 28 controls with minor medical problems (aged 7-18 years) were included. Parents completed Children's Sleep Habits Questionnaire (CSHQ) and Kinder Lebensqualitätsfragebogen: Children's Quality of Life Questionnaire-revised (KINDL-R) for patients and controls. Turgay DSM-IV Disruptive Behavior Disorders Rating Scale (T-DSM-IV-S) parent and teacher forms were used to assess ADHD symptoms for patients. Mothers of the patients completed Beck Depression Inventory and State-Trait Anxiety Inventory (STAI). Neurology clinic charts were reviewed for the epilepsy-related variables. Children with epilepsy had a higher CSHQ Total score than the control group. Those with a CSHQ score >56 (which indicates moderate to severe sleep problems) had lower scores on KINDL-R. Parent-rated T-DSM-IV-S Total and Hyperactivity-Impulsivity scores, STAI trait and Beck scores were found to be higher in those with a CSHQ score >56. Significant positive correlations were found between CSHQ Total score and T-DSM-IV-S, STAI trait and Beck scores. Binary logistic regression analysis revealed that T-DSM-IV-S Total, Inattention and Hyperactivity-Impulsivity scores were significantly associated with a higher CSHQ Total score. None of the epilepsy-related variables were found to be related with the CSHQ Total score. Among children with epilepsy, sleep problems lead to a poor quality of life. The link between sleep problems and psychiatric symptoms must be conceptualized as a bilateral relationship. ADHD appears to be the strongest predictor of sleep problems. Copyright © 2016 British Epilepsy Association. Published by Elsevier Ltd. All rights

  11. I/O-Efficient Algorithms for Problems on Grid-Based Terrains

    DEFF Research Database (Denmark)

    Arge, Lars Allan; Toma, Laura; Vitter, Jeffrey Scott

    2001-01-01

    The potential and use of Geographic Information Systems is rapidly increasing due to the increasing availability of massive amounts of geospatial data from projects like NASA's Mission to Planet Earth. However, the use of these massive datasets also exposes scalability problems with existing GIS...... hydrologic attributes of a terrain. We present the results of an extensive set of experiments on real-life terrain datasets of different sizes and characteristics. Our experiments show that while our new algorithm scales nicely with dataset size, the previously known algorithm "breaks down" once the size...

  12. Life: Here? There? Elsewhere? The Search for Life on Venus and Mars. Life in the Universe Series.

    Science.gov (United States)

    1996

    This classroom kit, designed by curriculum developers working with teachers and scientists from the SETI (Search for Extraterrestrial Intelligence) Institute, helps teachers guide students in the exploration of life through the multidisciplinary sciences of paleontology and exobiology. It reflects the real-life methods of science: making…

  13. Psychological needs, purpose in life, and problem video game playing among Chinese young adults

    OpenAIRE

    Wu, Anise M. S.; Lei, Lamis L. M.; Ku, L.

    2012-01-01

    The negative impacts of excessive and problematic video game playing on both children and adults are attracting increasing concern. Based on self-determination theory (SDT; Ryan & Deci, 2000), this study hypothesized that the three basic psychological needs of autonomy, competence, and relatedness are positively associated with purpose in life, which in turn acts as a protective factor against problem video game playing among Chinese young adult players. Through a questionnaire survey with a ...

  14. Evaluating usability of the Halden Reactor Large Screen Display. Is the Information Rich Design concept suitable for real-world installations?

    International Nuclear Information System (INIS)

    Braseth, Alf Ove

    2013-01-01

    Large Screen Displays (LSDs) are beginning to supplement desktop displays in modern control rooms, having the potential to display the big picture of complex processes. Information Rich Design (IRD) is a LSD concept used in many real-life installations in the petroleum domain, and more recently in nuclear research applications. The objectives of IRD are to provide the big picture, avoiding keyhole related problems while supporting fast visual perception of larger data sets. Two LSDs based on the IRD concept have been developed for large-scale nuclear simulators for research purposes; they have however suffered from unsatisfying user experience. The new Halden Reactor LSD, used to monitor a nuclear research reactor, was designed according to recent proposed Design Principles compiled in this paper to mitigate previously experienced problems. This paper evaluates the usability of the Halden Reactor LSD, comparing usability data with the replaced analogue panel, and data for an older IRD large screen display. The results suggest that the IRD concept is suitable for use in real-life applications from a user experience point of view, and that the recently proposed Design Principles have had a positive effect on usability. (author)

  15. Towards Real-Time Argumentation

    Directory of Open Access Journals (Sweden)

    Vicente JULIÁN

    2016-07-01

    Full Text Available In this paper, we deal with the problem of real-time coordination with the more general approach of reaching real-time agreements in MAS. Concretely, this work proposes a real-time argumentation framework in an attempt to provide agents with the ability of engaging in argumentative dialogues and come with a solution for their underlying agreement process within a bounded period of time. The framework has been implemented and evaluated in the domain of a customer support application. Concretely, we consider a society of agents that act on behalf of a group of technicians that must solve problems in a Technology Management Centre (TMC within a bounded time. This centre controls every process implicated in the provision of technological and customer support services to private or public organisations by means of a call centre. The contract signed between the TCM and the customer establishes penalties if the specified time is exceeded.

  16. An Introduction to Optimal Control Problems in Life Sciences and Economics From Mathematical Models to Numerical Simulation with MATLAB®

    CERN Document Server

    Anita, Sebastian; Capasso, Vincenzo

    2011-01-01

    Combining control theory and modeling, this textbook introduces and builds on methods for simulating and tackling concrete problems in a variety of applied sciences. Emphasizing "learning by doing," the authors focus on examples and applications to real-world problems. An elementary presentation of advanced concepts, proofs to introduce new ideas, and carefully presented MATLAB(R) programs help foster an understanding of the basics, but also lead the way to new, independent research. With minimal prerequisites and exercises in each chapter, this work serves as an excellent textbook a

  17. An economic lot and delivery scheduling problem with the fuzzy shelf life in a flexible job shop with unrelated parallel machines

    Directory of Open Access Journals (Sweden)

    S. Dousthaghi

    2012-08-01

    Full Text Available This paper considers an economic lot and delivery scheduling problem (ELDSP in a fuzzy environment with the fuzzy shelf life for each product. This problem is formulated in a flexible job shop with unrelated parallel machines, when the planning horizon is finite and it determines lot sizing, scheduling and sequencing, simultaneously. The proposed model of this paper is based on the basic period (BP approach. In this paper, a mixed-integer nonlinear programming (MINLP model is presented and then it is changed into two models in the fuzzy shelf life. The main model is dependent to the multiple basic periods and it is difficult to solve the resulted proposed model for large-scale problems in reasonable amount of time; thus, an efficient heuristic method is proposed to solve the problem. The performance of the proposed model is demonstrated using some numerical examples.

  18. Basic real analysis

    CERN Document Server

    Sohrab, Houshang H

    2014-01-01

    This expanded second edition presents the fundamentals and touchstone results of real analysis in full rigor, but in a style that requires little prior familiarity with proofs or mathematical language. The text is a comprehensive and largely self-contained introduction to the theory of real-valued functions of a real variable. The chapters on Lebesgue measure and integral have been rewritten entirely and greatly improved. They now contain Lebesgue’s differentiation theorem as well as his versions of the Fundamental Theorem(s) of Calculus. With expanded chapters, additional problems, and an expansive solutions manual, Basic Real Analysis, Second Edition, is ideal for senior undergraduates and first-year graduate students, both as a classroom text and a self-study guide. Reviews of first edition: The book is a clear and well-structured introduction to real analysis aimed at senior undergraduate and beginning graduate students. The prerequisites are few, but a certain mathematical sophistication is required. ....

  19. Emotional and behavioural problems in childhood and distress in adult life: risk and protective factors.

    Science.gov (United States)

    Buchanan, Ann; Flouri, Eirini; Ten Brinke, JoAnn

    2002-08-01

    To assess the relationship between risk and protective factors and the continuity of psychological problems from age 7 to age 33. Data on 5,591 cohort members of the National Child Development Study were used to track continuity and discontinuity between internalizing and externalizing problems at age 7, as assessed by the Rutter 'A' Health and Behaviour Checklist, and psychological distress at age 33, as assessed by the Malaise Inventory, controlling for risk and protective groupings present at age 7. There was no association between malaise in adulthood and internalizing problems in childhood. However, people who had externalizing problems in childhood were nearly twice as likely as those without such problems to have high Malaise scores in adulthood. A grouping of risk factors (police/probation experience by family, agency referral for difficulties in school, social services involvement, domestic tension) did not predict malaise in adulthood. Also a grouping of protective factors (outings with mother, father reads to child, good creative skills, good numeric skills) predicted that women were less likely to have high Malaise scores in adult life. Protective factors in childhood were strongly associated with lower Malaise scores in adulthood. Research on factors associated with discontinuity of psychological problems may prove fruitful.

  20. Gendered emotion work around physical health problems in mid- and later-life marriages.

    Science.gov (United States)

    Thomeer, Mieke Beth; Reczek, Corinne; Umberson, Debra

    2015-01-01

    The provision and receipt of emotion work-defined as intentional activities done to promote another's emotional well-being-are central dimensions of marriage. However, emotion work in response to physical health problems is a largely unexplored, yet likely important, aspect of the marital experience. We analyze dyadic in-depth interviews with husbands and wives in 21 mid- to later-life couples to examine the ways that health-impaired people and their spouses provide, interpret, and explain emotion work. Because physical health problems, emotion work, and marital dynamics are gendered, we consider how these processes differ for women and men. We find that wives provide emotion work regardless of their own health status. Husbands provide emotion work less consistently, typically only when the husbands see themselves as their wife's primary source of stability or when the husbands view their marriage as balanced. Notions of traditional masculinity preclude some husbands from providing emotion work even when their wife is health-impaired. This study articulates emotion work around physical health problems as one factor that sustains and exacerbates gender inequalities in marriage with implications for emotional and physical well-being. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Gendered emotion work around physical health problems in mid- and later-life marriages☆

    Science.gov (United States)

    Thomeer, Mieke Beth; Reczek, Corinne; Umberson, Debra

    2015-01-01

    The provision and receipt of emotion work—defined as intentional activities done to promote another’s emotional well-being—are central dimensions of marriage. However, emotion work in response to physical health problems is a largely unexplored, yet likely important, aspect of the marital experience. We analyze dyadic in-depth interviews with husbands and wives in 21 mid-to later-life couples to examine the ways that health-impaired people and their spouses provide, interpret, and explain emotion work. Because physical health problems, emotion work, and marital dynamics are gendered, we consider how these processes differ for women and men. We find that wives provide emotion work regardless of their own health status. Husbands provide emotion work less consistently, typically only when the husbands see themselves as their wife’s primary source of stability or when the husbands view their marriage as balanced. Notions of traditional masculinity preclude some husbands from providing emotion work even when their wife is health-impaired. This study articulates emotion work around physical health problems as one factor that sustains and exacerbates gender inequalities in marriage with implications for emotional and physical well-being. PMID:25661852

  2. Long-term treatment of ADHD with stimulants: A large observational study of real-life patients

    DEFF Research Database (Denmark)

    Powell, Shelagh G.; Thomsen, Per Hove; Frydenberg, Morten

    2011-01-01

    : The diversity of ADHD patients was evident from the comorbidity, age at start, comedication, and treatment needs over time. Dosages corresponded to guidelines in most patients, but some needed higher dosages or got along on lower dosages for long periods. Age at start and comorbidity influenced dosage......, and dosage was associated to differential outcome groups. Conclusion: The study findings underscored the diversity of ADHD patients and that individual factors should be taken into account when tailoring individual treatment schedules. Findings further showed that stimulant dosages are dynamic over time......Objective: To evaluate 410 real-life patients treated with stimulants and assessed systematically over several years. Method: Naturalistic observational study. A database was compiled on the basis of a review of the medical charts of patients attending a specialized ADHD clinic. Results...

  3. Facilitating Teacher Students’ Innovation Competence through Problem-Based Game Design Processes

    DEFF Research Database (Denmark)

    Hanghøj, Thorkild; Hovmand Sørensen, Sia

    2013-01-01

    and the interplay of different knowledge domains “inside” and “outside” of teacher education. By taking a mixed methods approach, we combine qualitative and quantitative methodologies for studying our case. This involved observations and interviews with selected groups as well as a post-camp survey with all......The aim of this paper is to describe how new teacher students develop innovation competence through problem-based game design processes by participating in an intro camp. The intro camp was held for 350 new teacher students at a Danish university college in 2011, which were asked to solve the real......-life problems of local schools by designing game solutions to be presented for and assessed by participating school directors and pupils. Based upon a pragmatist theoretical framework, we conceptualize the students’ development of innovation competence in relation to creative problem-solving, game frames...

  4. Bringing problem based learning to life using virtual reality.

    Science.gov (United States)

    Nelson, Linda; Sadler, Lynne; Surtees, Geoffrey

    2005-03-01

    Recent UK government policy advocates the need for a more flexible approach to nurse education and ;Fitness for Practice' stresses the importance of information technology and computer mediated learning facilities in the future of nursing education [Department of Health, Making a Difference, Strengthening the Nursing, Midwifery and Health Visiting Contribution to Health Care, Department of Health, 1999; The United Kingdom Central Council For Nursing, Fitness for Practice, The UKCC Commission for Nursing and Midwifery Education, 1999]. In response to this recommendation, a virtual reality package has been designed as a learning resource within adult pre-registration nursing education. This learning and teaching strategy is used in conjunction with problem based learning, enabling students to visualise individual/family life in a community setting. Students are encouraged to consider wider issues such as social and environmental factors and their impact upon health. The virtual reality package acts as one of a number of triggers. This paper will discuss the early development and offer an example of its use as a learning and teaching strategy within year two of a three year programme.

  5. TOUR CONSTRUCTION HEURISTICS FOR AN ORDER SEQUENCING PROBLEM

    Directory of Open Access Journals (Sweden)

    De Villiers, A. P.

    2012-11-01

    Full Text Available An order picking system that requires pickers to move in a clockwise direction around a picking line with fixed locations is considered. The problem is divided into three tiers. The tier in which orders must be sequenced is addressed. Eight tour construction heuristics are developed and implemented for an order picking system operating in unidirectional picking lines. Two classes of tour construction heuristics the tour construction starting position ( and the tour construction ending position ( are developed to sequence orders in a picking line. All algorithms are tested and compared using real life data sets. The best solution quality was obtained by a heuristic with adaptations.

  6. Adverse Life Events and Emotional and Behavioral Problems in Adolescence: The Role of Non-Verbal Cognitive Ability and Negative Cognitive Errors

    Science.gov (United States)

    Flouri, Eirini; Panourgia, Constantina

    2011-01-01

    The aim of this study was to test whether negative cognitive errors (overgeneralizing, catastrophizing, selective abstraction, and personalizing) mediate the moderator effect of non-verbal cognitive ability on the association between adverse life events (life stress) and emotional and behavioral problems in adolescence. The sample consisted of 430…

  7. Unified heuristics to solve routing problem of reverse logistics in sustainable supply chain

    Science.gov (United States)

    Anbuudayasankar, S. P.; Ganesh, K.; Lenny Koh, S. C.; Mohandas, K.

    2010-03-01

    A reverse logistics problem, motivated by many real-life applications, is examined where bottles/cans in which products are delivered from a processing depot to customers in one period are available for return to the depot in the following period. The picked-up bottles/cans need to be adjusted in the place of delivery load. This problem is termed as simultaneous delivery and pick-up problem with constrained capacity (SDPC). We develop three unified heuristics based on extended branch and bound heuristic, genetic algorithm and simulated annealing to solve SDPC. These heuristics are also designed to solve standard travelling salesman problem (TSP) and TSP with simultaneous delivery and pick-up (TSDP). We tested the heuristics on standard, derived and randomly generated datasets of TSP, TSDP and SDPC and obtained satisfying results with high convergence in reasonable time.

  8. Large neighborhood search for the double traveling salesman problem with multiple stacks

    Energy Technology Data Exchange (ETDEWEB)

    Bent, Russell W [Los Alamos National Laboratory; Van Hentenryck, Pascal [BROWN UNIV

    2009-01-01

    This paper considers a complex real-life short-haul/long haul pickup and delivery application. The problem can be modeled as double traveling salesman problem (TSP) in which the pickups and the deliveries happen in the first and second TSPs respectively. Moreover, the application features multiple stacks in which the items must be stored and the pickups and deliveries must take place in reserve (LIFO) order for each stack. The goal is to minimize the total travel time satisfying these constraints. This paper presents a large neighborhood search (LNS) algorithm which improves the best-known results on 65% of the available instances and is always within 2% of the best-known solutions.

  9. Lower and Upper Bounds for the Node, Edge, and Arc Routing Problem

    DEFF Research Database (Denmark)

    Bach, Lukas; Wøhlk, Sanne; Hasle, Geir

    The Node, Edge, and Arc Routing Problem (NEARP) was defined by Prins and Bouchenoua in 2004. They also proposed a memetic algorithm procedure and defined a set of test instances: the so-called CBMix benchmark. The NEARP generalizes the classical CVRP, the CARP, and the General Routing Problem...... for the CARP. We also define two novel sets of test instances to complement the CBMix benchmark. The first is based on well-known CARP instances; the second consists of real life cases of newspaper delivery routing. We provide numerical results in the form 1 of lower and best known upper bounds for all...... instances of all three benchmarks. For two of the instances, the gap is closed....

  10. Real cases study through computer applications for futures Agricultural Engineers

    Science.gov (United States)

    Moratiel, R.; Durán, J. M.; Tarquis, A. M.

    2010-05-01

    One of the huge concerns on the higher engineer education is the lag of real cases study that the future professionals need in the work and corporation market. This concern was reflected in Bologna higher education system including recommendations in this respect. The knowhow as why this or other methodology is one of the keys to resolve this problem. In the last courses given in Department of Crop Production, at the Agronomy Engineer School of Madrid (Escuela Técnica Superior de Ingenieros Agrónomos, UPM) we have developed more than one hundred applications in Microsoft Excel®. Our aim was to show different real scenarios which the future Agronomic Engineers can be found in their professional life and with items related to crop production field. In order to achieve our target, each application in Excel presents a file text in which is explained the theoretical concepts and the objectives, as well as some resources used from Excel syntax. In this way, the student can understand and use of such application, even they can modify and customize it for a real case presented in their context and/or master project. This electronic monograph gives an answer to the need to manage data in several real scenarios showed in lectures, calculus resolution, information analysis and manage worksheets in a professional and student level.

  11. A Parallel Biological Optimization Algorithm to Solve the Unbalanced Assignment Problem Based on DNA Molecular Computing

    Directory of Open Access Journals (Sweden)

    Zhaocai Wang

    2015-10-01

    Full Text Available The unbalanced assignment problem (UAP is to optimally resolve the problem of assigning n jobs to m individuals (m < n, such that minimum cost or maximum profit obtained. It is a vitally important Non-deterministic Polynomial (NP complete problem in operation management and applied mathematics, having numerous real life applications. In this paper, we present a new parallel DNA algorithm for solving the unbalanced assignment problem using DNA molecular operations. We reasonably design flexible-length DNA strands representing different jobs and individuals, take appropriate steps, and get the solutions of the UAP in the proper length range and O(mn time. We extend the application of DNA molecular operations and simultaneity to simplify the complexity of the computation.

  12. Multiobjective Two-Stage Stochastic Programming Problems with Interval Discrete Random Variables

    Directory of Open Access Journals (Sweden)

    S. K. Barik

    2012-01-01

    Full Text Available Most of the real-life decision-making problems have more than one conflicting and incommensurable objective functions. In this paper, we present a multiobjective two-stage stochastic linear programming problem considering some parameters of the linear constraints as interval type discrete random variables with known probability distribution. Randomness of the discrete intervals are considered for the model parameters. Further, the concepts of best optimum and worst optimum solution are analyzed in two-stage stochastic programming. To solve the stated problem, first we remove the randomness of the problem and formulate an equivalent deterministic linear programming model with multiobjective interval coefficients. Then the deterministic multiobjective model is solved using weighting method, where we apply the solution procedure of interval linear programming technique. We obtain the upper and lower bound of the objective function as the best and the worst value, respectively. It highlights the possible risk involved in the decision-making tool. A numerical example is presented to demonstrate the proposed solution procedure.

  13. DETERMINATION OF THE STRUCTURAL COMPONENTS OF LIFE COMPETENCE IN STUDENTS OF CLASSICAL UNIVERSITIES

    Directory of Open Access Journals (Sweden)

    Liudmyla Zubkova

    2016-11-01

    Full Text Available Nowadays, life competence of a person plays a very important role as it helps to solve effectively problems that every person can face in his/her life. Nevertheless, contemporary students show an unsatisfactory level of life competence, so it is very important for teachers in high education to pay attention to its formation. It was found that structural components of life competence have been researched by such scientists as M. Stepanenko, N. Nischeta, L. Scherbakova and others. However, in our opinion structural components of life competence should be generalized, so it is the purpose of our article. It is in studies revealing that there is no unified point of view of life competence structural components. In particular, scientists have distinguished such life competence structural components as 1 meta anthropologic, individual and personal, contextual, and social components (M. Stepanenko; 2 self-conception, axiological values, emotional and characterful components (V. Nischeta, 3 social, educative, communicative, and auto psychological components (L. Scherbakova. It should be noticed that the meta anthropologic component concentrates on the ability of a person to reflect individually main attributes of a human life; the individual and personal component focuses on self-identification and self-realization; the contextual component considers the ability of an individual to take real-life situations in good sense; the social component focuses on personal ability to solve real-life tasks regarding to social circumstances. The educative component of life competence includes knowledge of educational process essence and specific features of higher educational establishments. The communicative component represents knowledge about the role of communication in life success strategy. Taking into account scientists’ opinion and the author’s consideration it is concluded that the elucidation and generalization of life competence structural components

  14. Excel 2013 for biological and life sciences statistics a guide to solving practical problems

    CERN Document Server

    Quirk, Thomas J; Horton, Howard F

    2015-01-01

    This is the first book to show the capabilities of Microsoft Excel to teach biological and life sciences statistics effectively.  It is a step-by-step exercise-driven guide for students and practitioners who need to master Excel to solve practical science problems.  If understanding statistics isn’t your strongest suit, you are not especially mathematically-inclined, or if you are wary of computers, this is the right book for you.  Each chapter explains statistical formulas and directs the reader to use Excel commands to solve specific, easy-to-understand science problems.  Practice problems are provided at the end of each chapter with their solutions in an appendix.  Separately, there is a full Practice Test (with answers in an Appendix) that allows readers to test what they have learned.  Includes 164 illustrations in color Suitable for undergraduates or graduate student Prof. Tom Quirk is currently a Professor of Marketing at The Walker School of Business and Technology at Webster University in St....

  15. Clinical Characteristics of Patients with Newly Diagnosed Diabetic Macular Edema in Turkey: A Real-Life Registry Study—TURK-DEM

    Directory of Open Access Journals (Sweden)

    Bora Eldem

    2017-01-01

    Full Text Available Purpose. To evaluate the clinical and diagnostic characteristics of patients with newly diagnosed diabetic macular edema (DME in Turkey in a real-life setting. Methods. A total of 945 consecutive patients (mean (SD age: 61.3 (9.9 years, 55.2% male with newly diagnosed DME were included. Data on patient demographics, comorbidities, ocular history, ophthalmic examination findings including type of DME, central macular thickness (CMT via time domain (TD and spectral domain (SD optical coherence tomography (OCT, and planned treatments were recorded. Results. OCT (98.8% and fundoscopy (92.9% were the two most common diagnostic methods. Diffuse and focal DMEs were detected in 39.2% and 36.9% of cases, respectively. Laser photocoagulation (32.1% and antivascular endothelial growth factors (anti-VEGF; 31.8% were the most commonly planned treatments. The median CMT in the right eye was significantly greater in untreated than in treated patients [376.5 μm (range: 160–840 versus 342 μm (range: 146–999 (p=0.002] and in the left eye [370 μm (range: 201–780 versus 329 μm (range: 148–999 (p<0.001]. Conclusions. This study is the first large-scale real-life registry of DME patients in Turkey. SD-OCT and fundoscopy were the most common diagnostic methods. Laser photocoagulation and anti-VEGF therapy were the most common treatments.

  16. The assessment of recalled parental rearing behavior and its relationship to life satisfaction and interpersonal problems: a general population study

    Directory of Open Access Journals (Sweden)

    Hinz Andreas

    2009-03-01

    Full Text Available Abstract Background Parental rearing behavior is a significant etiological factor for the vulnerability of psychopathology and has been an issue of clinical research for a long time. For this scope instruments are important who asses economically recalled parental rearing behavior in a clinical practice. Therefore, a short German instrument for the assessment of the recalled parental rearing behavior Fragebogen zum erinnerten elterlichen Erziehungsverhalten (FEE was psychometrically evaluated [Recalled Parental Rearing Behavior]. Methods This questionnaire was evaluated in a representative population sample (N = 2.948 in Germany which included 44.2% male and 55.8% female persons with a mean age of M = 47.35 (SD = 17.10, range = 18–92. For the content evaluation of the FEE the Life Satisfaction Questionnaire (FLZ and the Inventory of Interpersonal Problems (IIP was filled out by the participants. Results The FEE scales yielded a good to satisfactory internal consistency and split-half reliability. Its three factors (rejection/punishment, emotional warmth, control/overprotection correlated positively with most of the areas of life satisfaction. Furthermore, positive associations between interpersonal problems and parental rejection and control could be identified. Conclusion The FEE is a short, reliable and valid instrument that can be applied in the clinical practice. In addition, the data proved an association between recalled parental rearing behavior, life satisfaction and interpersonal problems conform to the literature. Finally, specific problems with the retrospective assessment of parental rearing behavior were addressed as well.

  17. Modeling of the fatigue damage accumulation processes in the material of NPP design units under thermomechanical unstationary effects. Estimation of spent life and forecast of residual life

    International Nuclear Information System (INIS)

    Kiriushin, A.I.; Korotkikh, Yu.G.; Gorodov, G.F.

    2002-01-01

    Full text: The estimation problems of spent life and forecast of residual life of NPP equipment design units, operated at unstationary thermal force loads are considered. These loads are, as a rule, unregular and cause rotation of main stress tensor platforms of the most loaded zones of structural elements and viscoelastic plastic deformation of material in the places of stresses concentrations. The existing engineering approaches to the damages accumulation processes calculation in the material of structural units, their advantages and disadvantages are analyzed. For the processes of fatigue damages accumulation a model is proposed, which allows to take into account the unregular pattern of deformation multiaxiality of stressed state, rotation of main platforms, non-linear summation of damages at the loading mode change. The model in based on the equations of damaged medium mechanics, including the equations of viscoplastic deformation of the material and evolutionary equations of damages accumulation. The algorithms of spent life estimation and residual life forecast of the controlled equipment and systems zones are made on the bases of the given model by the known real history of loading, which is determined by real model of NPP operation. The results of numerical experiments on the basis of given model for various processes of thermal force loads and their comparison with experimental results are presented. (author)

  18. Slowed ageing, welfare, and population problems.

    Science.gov (United States)

    Wareham, Christopher

    2015-10-01

    Biological studies have demonstrated that it is possible to slow the ageing process and extend lifespan in a wide variety of organisms, perhaps including humans. Making use of the findings of these studies, this article examines two problems concerning the effect of life extension on population size and welfare. The first--the problem of overpopulation--is that as a result of life extension too many people will co-exist at the same time, resulting in decreases in average welfare. The second--the problem of underpopulation--is that life extension will result in too few people existing across time, resulting in decreases in total welfare. I argue that overpopulation is highly unlikely to result from technologies that slow ageing. Moreover, I claim that the problem of underpopulation relies on claims about life extension that are false in the case of life extension by slowed ageing. The upshot of these arguments is that the population problems discussed provide scant reason to oppose life extension by slowed ageing.

  19. Health-related quality of life among children with mental health problems: a population-based approach

    Directory of Open Access Journals (Sweden)

    Dey Michelle

    2012-06-01

    Full Text Available Abstract Background Children with mental health problems have been neglected in health-related quality of life (HRQOL studies. Therefore, the aims of the current study were 1 to assess the influence of the presence of mental or physical health problems on HRQOL; and 2 to analyze the effects of item overlap between mental health problems and HRQOL-measurements. Methods Proxy- and self-rated HRQOL (KIDSCREEN-27 of children 9–14 years old was assessed across children with mental health problems (n = 535, children with physical health problems (n = 327, and healthy controls (n = 744. Multiple linear regression analyses were conducted with health status, severity of symptoms, status of medication use, gender and nationality as independent, and HRQOL scores as dependent variables. The effects of item overlap were analyzed by repeating regression analyses while excluding those HRQOL items that contextually overlapped the most frequently-occurring mental health problem (attention deficits. Results Severity of symptoms was the strongest predictor of reduced HRQOL. However, all other predictors (except for the status of medication use also contributed to the prediction of some HRQOL scores. Controlling for item overlap did not meaningfully alter the results. Conclusions When children with different health constraints are compared, the severity of their particular health problems should be considered. Furthermore, item overlap seems not to be a major problem when the HRQOL of children with mental health problems is studied. Hence, HRQOL assessments are useful to gather information that goes beyond the clinical symptoms of a health problem. This information can, for instance, be used to improve clinical practice.

  20. Decreased health-related quality of life in patients with diabetic foot problems

    Science.gov (United States)

    Sothornwit, Jin; Srisawasdi, Gulapar; Suwannakin, Atchara; Sriwijitkamol, Apiradee

    2018-01-01

    Purpose The aim of this study was to investigate health-related quality of life (HRQoL) in patients with diabetic foot problems and compare the HRQoL between diabetic patients with: 1) diabetic foot problems (DF), including diabetic foot ulcer (DFU) or amputation (AMPU); 2) other diabetic complications (COM), such as diabetic retinopathy (DR), end-stage renal disease (ESRD), or coronary artery disease (CAD); and 3) no diabetic complication (CON). Patients and methods A total of 254 diabetic patients were studied in a cross-sectional setting. HRQoL was evaluated using Thai version of the Euro Quality of Life Questionnaire (EuroQoL), with five dimensions and five-level scale (EQ-5D-5L). Utility scores were calculated using time trade-off methods. Results A total of 141 patients in the DF group (98 DFU and 43 AMPU groups), 82 in the COM group (27 DR, 28 ESRD, and 27 CAD groups), and 31 in the CON group were interviewed. The mean age was 63.2±12.1 years, body mass index was 24.9±4.7 kg/m2, mean hemoglobin A1c was 7.7±2.1%, duration of diabetes was 13.1±9.9 years, and the mean utility scores were 0.799±0.25. After having DF, 21% of patients had lost their jobs. The COM group had lower utility scores than the CON group. Among the diabetic complications, the DF group had the lowest mean utility scores as compared to the COM and CON groups (0.703±0.28 in the DF group, 0.903±0.15 in the COM group, and 0.961±0.06 in the CON group, Pdiabetic foot care should be emphasized in clinical practice to prevent foot complications. PMID:29563821

  1. Decreased health-related quality of life in patients with diabetic foot problems.

    Science.gov (United States)

    Sothornwit, Jin; Srisawasdi, Gulapar; Suwannakin, Atchara; Sriwijitkamol, Apiradee

    2018-01-01

    The aim of this study was to investigate health-related quality of life (HRQoL) in patients with diabetic foot problems and compare the HRQoL between diabetic patients with: 1) diabetic foot problems (DF), including diabetic foot ulcer (DFU) or amputation (AMPU); 2) other diabetic complications (COM), such as diabetic retinopathy (DR), end-stage renal disease (ESRD), or coronary artery disease (CAD); and 3) no diabetic complication (CON). A total of 254 diabetic patients were studied in a cross-sectional setting. HRQoL was evaluated using Thai version of the Euro Quality of Life Questionnaire (EuroQoL), with five dimensions and five-level scale (EQ-5D-5L). Utility scores were calculated using time trade-off methods. A total of 141 patients in the DF group (98 DFU and 43 AMPU groups), 82 in the COM group (27 DR, 28 ESRD, and 27 CAD groups), and 31 in the CON group were interviewed. The mean age was 63.2±12.1 years, body mass index was 24.9±4.7 kg/m 2 , mean hemoglobin A1c was 7.7±2.1%, duration of diabetes was 13.1±9.9 years, and the mean utility scores were 0.799±0.25. After having DF, 21% of patients had lost their jobs. The COM group had lower utility scores than the CON group. Among the diabetic complications, the DF group had the lowest mean utility scores as compared to the COM and CON groups (0.703±0.28 in the DF group, 0.903±0.15 in the COM group, and 0.961±0.06 in the CON group, P diabetic foot care should be emphasized in clinical practice to prevent foot complications.

  2. Calculus problems

    CERN Document Server

    Baronti, Marco; van der Putten, Robertus; Venturi, Irene

    2016-01-01

    This book, intended as a practical working guide for students in Engineering, Mathematics, Physics, or any other field where rigorous calculus is needed, includes 450 exercises. Each chapter starts with a summary of the main definitions and results, which is followed by a selection of solved exercises accompanied by brief, illustrative comments. A selection of problems with indicated solutions rounds out each chapter. A final chapter explores problems that are not designed with a single issue in mind but instead call for the combination of a variety of techniques, rounding out the book’s coverage. Though the book’s primary focus is on functions of one real variable, basic ordinary differential equations (separation of variables, linear first order and constant coefficients ODEs) are also discussed. The material is taken from actual written tests that have been delivered at the Engineering School of the University of Genoa. Literally thousands of students have worked on these problems, ensuring their real-...

  3. Problem Based Internship in Surveying and Planning Curricula

    DEFF Research Database (Denmark)

    Sørensen, Esben Munk; Enemark, Stig

    2006-01-01

    Programme has been divided into a 3 year Bachelor-Programme and after this a 2 year Master-Programme. It has been done as a part of a governmental policy to adapt and fulfil the Bologna-charter in all University Curricula in Denmark. A new element in the Master Programme is a problem-based internship...... economy and – leadership”. This course is organized as an e-Learning course and the student has to develop and document their skills to follow distance e-learning courses. It will prepare them to follow and organize self paced learning in virtual environment which will develop their capacity for life...... by the society to serve the community with still more new knowledge and technology transfer from the international research community. The internship and still more real world influenced problem based learning by writing thesis will be and important bridge builder in the following years....

  4. A Rule-Based Local Search Algorithm for General Shift Design Problems in Airport Ground Handling

    DEFF Research Database (Denmark)

    Clausen, Tommy

    We consider a generalized version of the shift design problem where shifts are created to cover a multiskilled demand and fit the parameters of the workforce. We present a collection of constraints and objectives for the generalized shift design problem. A local search solution framework with mul......We consider a generalized version of the shift design problem where shifts are created to cover a multiskilled demand and fit the parameters of the workforce. We present a collection of constraints and objectives for the generalized shift design problem. A local search solution framework...... with multiple neighborhoods and a loosely coupled rule engine based on simulated annealing is presented. Computational experiments on real-life data from various airport ground handling organization show the performance and flexibility of the proposed algorithm....

  5. Computer Virus: Their Problems & Major at-tacks in Real Life

    OpenAIRE

    Milind. J. Joshi; Bhaskar Vijayrao patil

    2012-01-01

    Today's enterprise networks are distributed to different geographical locations and applications are more centrally located, information represents the most important asset. With the growing number of data communication services, channels and available software applications, data are processed in large quantities and in a more efficient manner. This technological enhancement offers new flexible opportunities also measure security threats poses in the networks. These threats can external or In...

  6. Adverse life events as risk factors for behavioural and emotional problems in a 7-year follow-up of a population-based child cohort

    DEFF Research Database (Denmark)

    Rasmussen, Cathrine Skovmand; Nielsen, Louise Gramstrup; Petersen, Dorthe Janne

    2014-01-01

    on emotional and behavioural problems was obtained from parents filling in the Child Behavior Checklist (CBCL) when the child was 8-9 and again when 15 years old. Data on risk factors was drawn from Danish registers. Analysis used was logistic regression for crude and adjusted change. Results: Parental divorce......Background and aim: The aim of the study was to identify risk factors for significant changes in emotional and behavioural problem load in a community-based cohort of Danish children aged 9-16 years, the risk factors being seven parental and two child-related adverse life events. Methods: Data...... significantly raised the odds ratio of an increase in emotional and behavioural problems; furthermore, the risk of deterioration in problem behaviour rose significantly with increasing number of adverse life events. By dividing the children into four groups based on the pathway in problem load (increasers...

  7. A Cost Assessment of the Dayton Public Schools Vehicle Routing Problem

    Science.gov (United States)

    2009-03-01

    known problems: the Traveling Salesman Problem (TSP) and the Bin Packing Problem ( BPP ) (Ralphs, 2003). The VRP has a plethora of real world...well known problems: the Traveling Salesman Problem (TSP) and the Bin Packing Problem ( BPP ) (Ralphs, 2003). The VRP has a plethora of real world

  8. From combinatorial optimization to real algebraic geometry and back

    Directory of Open Access Journals (Sweden)

    Janez Povh

    2014-12-01

    Full Text Available In this paper, we explain the relations between combinatorial optimization and real algebraic geometry with a special focus to the quadratic assignment problem. We demonstrate how to write a quadratic optimization problem over discrete feasible set as a linear optimization problem over the cone of completely positive matrices. The latter formulation enables a hierarchy of approximations which rely on results from polynomial optimization, a sub-eld of real algebraic geometry.

  9. Grating-based guided-mode resonance devices and degradation of their performance in real-life conditions

    DEFF Research Database (Denmark)

    Ivinskaya, Aliaksandra; Bergmann, René; Kafka, Jan Robert

    2014-01-01

    Guided-mode resonances in structures having periodicity along at least one dimension were widely employed in the last decade in various optical devices. Initially it was shown that at frequencies close to the second order band gap periodic structures can feature total reflection of light due...... to the guided modes propagating along the surface of the grating. As an application, this allows to substitute a thick multilayer Bragg mirror in VCSELs by a thin grating-based mirror. Most devices utilizing guided-mode resonances were theoretically and numerically investigated with the idealized model...... of an infinite periodic structure illuminated by a plane wave. To see how grating-based components can perform in real life we take into account two critical factors: the finite size of the grating and the Gaussian shape of the light source replacing a plane wave. These factors can significantly change...

  10. Mathematical models and heuristic solutions for container positioning problems in port terminals

    DEFF Research Database (Denmark)

    Kallehauge, Louise Sibbesen

    2008-01-01

    presents an efficient solution algorithm for the CPP. Based on a number of new concepts, an event-based construction heuristic is developed and its ability to solve real-life problem instances is established. The backbone of the algorithm is a list of events, corresponding to a sequence of operations...... by constructing mathematical programming formulations of the problem and developing an efficient heuristic algorithm for its solution. The thesis consists of an introduction, two main chapters concerning new mathematical formulations and a new heuristic for the CPP, technical issues, computational results...... concerning the subject is reviewed. The research presented in this thesis is divided into two main parts: Construction and investigation of new mathematical programming formulations of the CPP and development and implementation of a new event-based heuristic for the problem. The first part presents three...

  11. Developing authentic problems through lived experiences in nature

    Science.gov (United States)

    Gürel, Zeynep

    2017-02-01

    This study's main objective is to develop a theoretical and ontological basis for experimentation in contact with the real life, oriented to physics education. Physics is built upon the observation of nature, where our experience provides opportunity to deal with science in natural environment to those learners who have background in the very basics and essentials of physics. Physics in Nature course includes visiting and camping experiences situated in nature and organizing camp with educational purposes. The course has been integrated with indoor and outdoor settings interactively and the authentic problems, which have been taken from outdoor settings, have been brought into the class without well-defined structure (Ill-structured problems). Within the period of ten years, there were plethora of events and problems that would provide sufficient material for many researchers. Because every problem is an event and has a story. The philosophical event concept of Deleuze and Guattari has been used in the events of Physics in Nature courses. Post-qualitative research methodology has been used in order to put forward how to construct the relation between physics and nature and become the main problem in the physics in nature, thereby it has been the basis of the course and our academic research

  12. Problem solving in relation to resources in everyday life in families of children with disabilities: a pilot study.

    Science.gov (United States)

    Ylvén, Regina; Granlund, Mats; Persson, Carina

    2012-06-01

    Problem solving is recognized as a skill, helping families of children with disabilities to manage problems in everyday life. Family problem-solving skills may therefore be seen as an important outcome of a child and youth habilitation service. The aim of this pilot feasibility study was to examine the design of a future web-based questionnaire study focusing on problem-solving patterns in relation to resources in families of children with disabilities. The descriptive statistical analyses built on data from 13 families and findings showed an overall satisfactory score distribution for three of the included instruments, whereas two instruments showed floor effects in one third of the items. Findings indicated design problems with data collection related to adapting questionnaires to a web-based survey format and to problems with the stop function that was added. Implementing the main study using web-based surveys needs critical considerations according to the choice of the web tool and the recruitment process.

  13. Complex analogues of real problems

    DEFF Research Database (Denmark)

    Esdahl-Schou, Rune

    This thesis will be a mix of different problems in number theory. As such it is split into two natural parts. The rst part focuses on normal numbers and construction of numbers that are normal to a given complex base. It is written in the style of a thorough and introductory paper on that subject....... Certain classical theorems are stated without proof but with a reference instead, though usually a proof is given. This part of the thesis represents the pinnacle of the authors work during the first two years of his PhD study. The work presented is greatly inspired by the work of Madritsch, Thuswaldner...... and Tichy in [Madritsch et al., 2008] and [Madritsch, 2008] and contains a generalisation of the main theorem in [Madritsch, 2008]. The second part of the thesis focuses on Diophantine approximation, mainly on a famous conjecture by Schmidt from the 1980s. This conjecture was solved by Badziahin, Pollington...

  14. The numbers game: quantitative analysis of Neorickettsia sp. propagation through complex life cycle of its digenean host using real-time qPCR.

    Science.gov (United States)

    Greiman, Stephen E; Tkach, Vasyl V

    2016-07-01

    Bacteria of the genus Neorickettsia are obligate intracellular endosymbionts of parasitic flukes (Digenea) and are passed through the entire complex life cycle of the parasite by vertical transmission. Several species of Neorickettsia are known to cause diseases in domestic animals, wildlife, and humans. Quantitative data on the transmission of the bacteria through the digenean life cycle is almost completely lacking. This study quantified for the first time the abundance of Neorickettsia within multiple stages of the life cycle of the digenean Plagiorchis elegans. Snails Lymnaea stagnalis collected from a pond in North Dakota were screened for the presence of digenean cercariae, which were subsequently tested for the presence of Neorickettsia. Three L. stagnalis were found shedding P. elegans cercariae infected with Neorickettsia. These snails were used to initiate three separate laboratory life cycles and obtain all life cycle stages for bacterial quantification. A quantitative real-time PCR assay targeting the GroEL gene was developed to enumerate Neorickettsia sp. within different stages of the digenean life cycle. The number of bacteria significantly increased throughout all stages, from eggs to adults. The two largest increases in number of bacteria occurred during the period from eggs to cercariae and from 6-day metacercariae to 48-h juvenile worms. These two periods seem to be the most important for Neorickettsia propagation through the complex digenean life cycle and maturation in the definitive host.

  15. Incorporating technology-based learning tools into teaching and learning of optimization problems

    Science.gov (United States)

    Yang, Irene

    2014-07-01

    The traditional approach of teaching optimization problems in calculus emphasizes more on teaching the students using analytical approach through a series of procedural steps. However, optimization normally involves problem solving in real life problems and most students fail to translate the problems into mathematic models and have difficulties to visualize the concept underlying. As an educator, it is essential to embed technology in suitable content areas to engage students in construction of meaningful learning by creating a technology-based learning environment. This paper presents the applications of technology-based learning tool in designing optimization learning activities with illustrative examples, as well as to address the challenges in the implementation of using technology in teaching and learning optimization. The suggestion activities in this paper allow flexibility for educator to modify their teaching strategy and apply technology to accommodate different level of studies for the topic of optimization. Hence, this provides great potential for a wide range of learners to enhance their understanding of the concept of optimization.

  16. The Vessel Schedule Recovery Problem (VSRP) – A MIP model for handling disruptions in liner shipping

    DEFF Research Database (Denmark)

    Brouer, Berit Dangaard; Dirksen, Jakob; Pisinger, David

    2013-01-01

    or even omitting one. We present the Vessel Schedule Recovery Problem (VSRP) to evaluate a given disruption scenario and to select a recovery action balancing the trade off between increased bunker consumption and the impact on cargo in the remaining network and the customer service level. It is proven...... due to adverse weather conditions, port contingencies, and many other issues. A common scenario for recovering a schedule is to either increase the speed at the cost of a significant increase in the fuel consumption or delaying cargo. Advanced recovery options might exist by swapping two port calls...... that the VSRP is NP-hard. The model is applied to four real life cases from Maersk Line and results are achieved in less than 5seconds with solutions comparable or superior to those chosen by operations managers in real life. Cost savings of up to 58% may be achieved by the suggested solutions compared...

  17. An Anomalous Noise Events Detector for Dynamic Road Traffic Noise Mapping in Real-Life Urban and Suburban Environments

    Directory of Open Access Journals (Sweden)

    Joan Claudi Socoró

    2017-10-01

    Full Text Available One of the main aspects affecting the quality of life of people living in urban and suburban areas is their continued exposure to high Road Traffic Noise (RTN levels. Until now, noise measurements in cities have been performed by professionals, recording data in certain locations to build a noise map afterwards. However, the deployment of Wireless Acoustic Sensor Networks (WASN has enabled automatic noise mapping in smart cities. In order to obtain a reliable picture of the RTN levels affecting citizens, Anomalous Noise Events (ANE unrelated to road traffic should be removed from the noise map computation. To this aim, this paper introduces an Anomalous Noise Event Detector (ANED designed to differentiate between RTN and ANE in real time within a predefined interval running on the distributed low-cost acoustic sensors of a WASN. The proposed ANED follows a two-class audio event detection and classification approach, instead of multi-class or one-class classification schemes, taking advantage of the collection of representative acoustic data in real-life environments. The experiments conducted within the DYNAMAP project, implemented on ARM-based acoustic sensors, show the feasibility of the proposal both in terms of computational cost and classification performance using standard Mel cepstral coefficients and Gaussian Mixture Models (GMM. The two-class GMM core classifier relatively improves the baseline universal GMM one-class classifier F1 measure by 18.7% and 31.8% for suburban and urban environments, respectively, within the 1-s integration interval. Nevertheless, according to the results, the classification performance of the current ANED implementation still has room for improvement.

  18. Treatment Efficacy and Compliance in Patients with Diabetic Macular Edema Treated with Ranibizumab in a Real-Life Setting

    Directory of Open Access Journals (Sweden)

    Anne-Laurence Best

    2018-01-01

    Full Text Available Purpose. To assess real-life efficacy of ranibizumab and treatment compliance of patients with vision loss secondary to diabetic macular edema (DME. Methods. A retrospective study was conducted in DME patients treated with ranibizumab. Patients were monitored every 4 weeks for visual acuity (VA and central retinal thickness (CRT by SD-OCT. All patients received a loading dose of 3 monthly injections followed by retreatments on an as-needed basis. The primary endpoint was the change in VA at M12. Patient compliance to the follow-up and the correlation between the injection number and VA were also investigated. Compliance was compared to that of neovascular age-related macular degeneration (nAMD patients. Results. Seventy-two eyes of 55 consecutive DME patients were included. At baseline, the mean VA was 56.5 letters and CRT was 470 μm. At M12, the mean VA was 63.4 letters (p 70 letters, the mean VA change was +6.9 letters, and the mean CRT was 361.9 μm (p=0.0001 after a mean number of 5.33 intravitreal injections. In patients who received ≥7 injections, the VA gain and final VA were significantly higher than in patients who received <7 injections. At M12, 25.45% of DME patients were lost to follow-up versus 16.8% of nAMD patients (n=55. Discussion/Conclusion. Our study confirms the real-life efficacy of ranibizumab in DME at M12 and the need for a large number of injections to achieve better visual outcomes. We also showed a trend to a lower compliance in diabetic versus nAMD patients.

  19. Introduction to Real Analysis An Educational Approach

    CERN Document Server

    Bauldry, William C

    2011-01-01

    An accessible introduction to real analysis and its connection to elementary calculus Bridging the gap between the development and history of real analysis, Introduction to Real Analysis: An Educational Approach presents a comprehensive introduction to real analysis while also offering a survey of the field. With its balance of historical background, key calculus methods, and hands-on applications, this book provides readers with a solid foundation and fundamental understanding of real analysis. The book begins with an outline of basic calculus, including a close examination of problems illust

  20. Moving through time: the role of personality in three real-life contexts.

    Science.gov (United States)

    Duffy, Sarah E; Feist, Michele I; McCarthy, Steven

    2014-01-01

    In English, two deictic space-time metaphors are in common usage: the Moving Ego metaphor conceptualizes the ego as moving forward through time and the Moving Time metaphor conceptualizes time as moving forward toward the ego (Clark, 1973). Although earlier research investigating the psychological reality of these metaphors has typically examined spatial influences on temporal reasoning (e.g., Boroditsky & Ramscar, 2002), recent lines of research have extended beyond this, providing initial evidence that personality differences and emotional experiences may also influence how people reason about events in time (Duffy & Feist, 2014; Hauser, Carter, & Meier, 2009; Richmond, Wilson, & Zinken, 2012). In this article, we investigate whether these relationships have force in real life. Building on the effects of individual differences in self-reported conscientiousness and procrastination found by Duffy and Feist (2014), we examined whether, in addition to self-reported conscientiousness and procrastination, there is a relationship between conscientious and procrastinating behaviors and temporal perspective. We found that participants who adopted the Moving Time perspective were more likely to exhibit conscientious behaviors, while those who adopted the Moving Ego perspective were more likely to procrastinate, suggesting that the earlier effects reach beyond the laboratory. Copyright © 2014 Cognitive Science Society, Inc.