The Cognition of Maximal Reach Distance in Parkinson’s Disease
Satoru Otsuki
2016-01-01
Full Text Available This study aimed to investigate whether the cognition of spatial distance in reaching movements was decreased in patients with Parkinson’s disease (PD and whether this cognition was associated with various symptoms of PD. Estimated and actual maximal reaching distances were measured in three directions in PD patients and healthy elderly volunteers. Differences between estimated and actual measurements were compared within each group. In the PD patients, the associations between “error in cognition” of reaching distance and “clinical findings” were also examined. The results showed that no differences were observed in any values regardless of dominance of hand and severity of symptoms. The differences between the estimated and actual measurements were negatively deviated in the PD patients, indicating that they tended to underestimate reaching distance. “Error in cognition” of reaching distance correlated with the items of posture in the motor section of the Unified Parkinson’s Disease Rating Scale. This suggests that, in PD patients, postural deviation and postural instability might affect the cognition of the distance from a target object.
Determinants of maximal oxygen uptake in severe acute hypoxia
Calbet, J A L; Boushel, Robert Christopher; Rådegran, G
2003-01-01
To unravel the mechanisms by which maximal oxygen uptake (VO2 max) is reduced with severe acute hypoxia in humans, nine Danish lowlanders performed incremental cycle ergometer exercise to exhaustion, while breathing room air (normoxia) or 10.5% O2 in N2 (hypoxia, approximately 5,300 m above sea...... level). With hypoxia, exercise PaO2 dropped to 31-34 mmHg and arterial O2 content (CaO2) was reduced by 35% (P ..., as reflected by the higher alveolar-arterial O2 difference in hypoxia (P stroke VOlume (P
Very slow search and reach: failure to maximize expected gain in an eye-hand coordination task.
Hang Zhang
Full Text Available We examined an eye-hand coordination task where optimal visual search and hand movement strategies were inter-related. Observers were asked to find and touch a target among five distractors on a touch screen. Their reward for touching the target was reduced by an amount proportional to how long they took to locate and reach to it. Coordinating the eye and the hand appropriately would markedly reduce the search-reach time. Using statistical decision theory we derived the sequence of interrelated eye and hand movements that would maximize expected gain and we predicted how hand movements should change as the eye gathered further information about target location. We recorded human observers' eye movements and hand movements and compared them with the optimal strategy that would have maximized expected gain. We found that most observers failed to adopt the optimal search-reach strategy. We analyze and describe the strategies they did adopt.
A comparison of the spine posture among several sit-and-reach test protocols.
Miñarro, Pedro A López; Andújar, Pilar Sáinz de Baranda; García, Pedro L Rodríguez; Toro, Enrique Ortega
2007-12-01
The purpose of the study was to compare the thoracic and lumbar spine posture among different sit-and-reach tests. Fifty-eight men and 47 women were asked to perform three trials of sit-and-reach test (SR), toe-touch test (TT), back-saver sit-and-reach test (BS) right and left, unilateral seated sit-and-reach test (USR) right and left, and V sit-and-reach test (VSR). Thoracic and lumbar angles were assessed with an inclinometer when subjects reached forward maximally. Women had a lower thoracic angle than men on all tests (pspine when compared to other tests (30.5 degrees in men and 32.0 degrees in women). Unilateral seated sit-and-reach test presented the lowest lumbar angle in men (24.2 degrees for right leg and 23.9 degrees for left leg) and women (23.9 degrees in both legs) and there were significant differences with respect to the other tests. Characteristics and administration procedures of tests, such us uni- or bilateral, sitting or standing, measuring with or without box, parallel or V position, and hip position influence thoracic and lumbar postures.
Maximal respiratory static pressures in patients with different stages of COPD severity
Ricci Alberto
2008-01-01
Full Text Available Abstract Background In this study, we analyzed maximal inspiratory pressure (MIP and maximal expiratory pressure (MEP values in a stable COPD population compared with normal subjects. We evaluated the possible correlation between functional maximal respiratory static pressures and functional and anthropometric parameters at different stages of COPD. Furthermore, we considered the possible correlation between airway obstruction and MIP and MEP values. Subject and methods 110 patients with stable COPD and 21 age-matched healthy subjects were enrolled in this study. Patients were subdivided according to GOLD guidelines: 31 mild, 39 moderate and 28 severe. Results Both MIP and MEP were lower in patients with severe airway impairment than in normal subjects. Moreover, we found a correlation between respiratory muscle function and some functional and anthropometric parameters: FEV1 (forced expiratory volume in one second, FVC (forced vital capacity, PEF (peak expiratory flow, TLC (total lung capacity and height. MIP and MEP values were lower in patients with severe impairment than in patients with a slight reduction of FEV1. Conclusion The measurement of MIP and MEP indicates the state of respiratory muscles, thus providing clinicians with a further and helpful tool in monitoring the evolution of COPD.
Elisabeth Edvardsen
Full Text Available OBJECTIVE: To describe different end criteria for reaching maximal oxygen uptake (VO2max during a continuous graded exercise test on the treadmill, and to explore the manner by which different end criteria have an impact on the magnitude of the VO2max result. METHODS: A sample of 861 individuals (390 women aged 20-85 years performed an exercise test on a treadmill until exhaustion. Gas exchange, heart rate, blood lactate concentration and Borg Scale6-20 rating were measured, and the impact of different end criteria on VO2max was studied;VO2 leveling off, maximal heart rate (HRmax, different levels of respiratory exchange ratio (RER, and postexercise blood lactate concentration. RESULTS: Eight hundred and four healthy participants (93% fulfilled the exercise test until voluntary exhaustion. There were no sex-related differences in HRmax, RER, or Borg Scale rating, whereas blood lactate concentration was 18% lower in women (P<0.001. Forty-two percent of the participants achieved a plateau in VO2; these individuals had 5% higher ventilation (P = 0.033, 4% higher RER (P<0.001, and 5% higher blood lactate concentration (P = 0.047 compared with participants who did not reach a VO2 plateau. When using RER ≥1.15 or blood lactate concentration ≥8.0 mmol•L(-1, VO2max was 4% (P = 0.012 and 10% greater (P<0.001, respectively. A blood lactate concentration ≥8.0 mmol•L(-1 excluded 63% of the participants in the 50-85-year-old cohort. CONCLUSIONS: A range of typical end criteria are presented in a random sample of subjects aged 20-85 years. The choice of end criteria will have an impact on the number of the participants as well as the VO2max outcome. Suggestions for new recommendations are given.
Ellis, Michael D; Schut, Ingrid; Dewald, Julius P A
2017-07-01
Pharmaceutical intervention targets arm flexor spasticity with an often-unsuccessful goal of improving function. Flexion synergy is a related motor impairment that may be inadvertently neglected. Here, flexor spasticity and flexion synergy are disentangled to determine their contributions to reaching dysfunction. Twenty-six individuals participated. A robotic device systematically modulated shoulder abduction loading during ballistic reaching. Elbow muscle electromyography data were partitioned into windows delineated by elbow joint velocity allowing for the separation of synergy- and spasticity-related activation. Reaching velocity decreased with abduction loading (pstroke recovery trials. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.
Zhou, Meirong; Xia, Junqiang; Lu, Jinyou; Deng, Shanshan; Lin, Fenfen
2017-05-01
In the past 50 years, the Shishou reach in the middle Yangtze River underwent significant channel evolution owing to the implementation of an artificial cutoff, the construction of bank revetment works and the operation of the Three Gorges Project (TGP). Based on the measured hydrological data and topographic data, the processes of channel evolution in this reach were investigated mainly from the adjustments in planform and cross-sectional geometries. The variation in planform geometry obtained in this study indicates that (i) the artificial cutoff at Zhongzhouzi caused the river regime to adjust drastically, with the mean rate of thalweg migration at reach scale of 42.0 m/a over the period 1966-1975; (ii) then the effect of this artificial cutoff reduced gradually, with the mean migration rate decreasing to 40 m/a owing to the occurrence of high water levels in 1993-1998; and (iii) the average annual rate of thalweg migration decreased to 29.3 m/a because of the impacts of various bank protection engineering and the TGP operation during the period 2002-2015. However, remarkable thalweg migration processes still occurred in local regions after the TGP operation, which resulted in significant bankline migration in local reaches of Beimenkou, Shijiatai, and Tiaoxiankou. In addition, the adjustments of bankfull channel geometry were investigated at section and reach scales after the TGP operation. Calculated results show that lateral channel migration in this reach was restricted by various river regulation works and that channel evolution was mainly characterized by an increase in bankfull depth and cross-sectional area. Empirical relationships were developed between the reach-scale bankfull dimensions (depth and area), the bankfull widths at specified sections, and the previous 5-year average fluvial erosion intensity during flood seasons, with high correlation degrees between them being obtained.
Villadsen, Allan; Roos, Ewa M.; Overgaard, Søren
Abstract : Purpose To evaluate the reliability of single-joint and multi-joint maximal leg muscle power and functional performance measures in patients with severe OA. Background Muscle power, taking both strength and velocity into account, is a more functional measure of lower extremity muscle a...
Brendle, Joerg
2016-01-01
We show that, consistently, there can be maximal subtrees of P (omega) and P (omega) / fin of arbitrary regular uncountable size below the size of the continuum. We also show that there are no maximal subtrees of P (omega) / fin with countable levels. Our results answer several questions of Campero, Cancino, Hrusak, and Miranda.
Maximizing cost-effectiveness by adjusting treatment strategy according to glaucoma severity
Guedes, Ricardo Augusto Paletta; Guedes, Vanessa Maria Paletta; Gomes, Carlos Eduardo de Mello; Chaoubah, Alfredo
2016-01-01
Abstract Background: The aim of this study is to determine the most cost-effective strategy for the treatment of primary open-angle glaucoma (POAG) in Brazil, from the payer's perspective (Brazilian Public Health System) in the setting of the Glaucoma Referral Centers. Methods: Study design was a cost-effectiveness analysis of different treatment strategies for POAG. We developed 3 Markov models (one for each glaucoma stage: early, moderate and advanced), using a hypothetical cohort of POAG patients, from the perspective of the Brazilian Public Health System (SUS) and a horizon of the average life expectancy of the Brazilian population. Different strategies were tested according to disease severity. For early glaucoma, we compared observation, laser and medications. For moderate glaucoma, medications, laser and surgery. For advanced glaucoma, medications and surgery. Main outcome measures were ICER (incremental cost-effectiveness ratio), medical direct costs and QALY (quality-adjusted life year). Results: In early glaucoma, both laser and medical treatment were cost-effective (ICERs of initial laser and initial medical treatment over observation only, were R$ 2,811.39/QALY and R$ 3,450.47/QALY). Compared to observation strategy, the two alternatives have provided significant gains in quality of life. In moderate glaucoma population, medical treatment presented the highest costs among treatment strategies. Both laser and surgery were highly cost-effective in this group. For advanced glaucoma, both tested strategies were cost-effective. Starting age had a great impact on results in all studied groups. Initiating glaucoma therapy using laser or surgery were more cost-effective, the younger the patient. Conclusion: All tested treatment strategies for glaucoma provided real gains in quality of life and were cost-effective. However, according to the disease severity, not all strategies provided the same cost-effectiveness profile. Based on our findings, there should be a
Mary P McGowan
Full Text Available OBJECTIVES: Mipomersen, an antisense oligonucleotide targeting apolipoprotein B synthesis, significantly reduces LDL-C and other atherogenic lipoproteins in familial hypercholesterolemia when added to ongoing maximally tolerated lipid-lowering therapy. Safety and efficacy of mipomersen in patients with severe hypercholesterolemia was evaluated. METHODS AND RESULTS: Randomized, double-blind, placebo-controlled, multicenter trial. Patients (n = 58 were ≥18 years with LDL-C ≥7.8 mmol/L or LDL-C ≥5.1 mmol/L plus CHD disease, on maximally tolerated lipid-lowering therapy that excluded apheresis. Weekly subcutaneous injections of mipomersen 200 mg (n = 39 or placebo (n = 19 were added to lipid-lowering therapy for 26 weeks. MAIN OUTCOME: percent reduction in LDL-C from baseline to 2 weeks after the last dose of treatment. Mipomersen (n = 27 reduced LDL-C by 36%, from a baseline of 7.2 mmol/L, for a mean absolute reduction of 2.6 mmol/L. Conversely, mean LDL-C increased 13% in placebo (n = 18 from a baseline of 6.5 mmol/L (mipomersen vs placebo p<0.001. Mipomersen produced statistically significant (p<0.001 reductions in apolipoprotein B and lipoprotein(a, with no change in high-density lipoprotein cholesterol. Mild-to-moderate injection site reactions were the most frequently reported adverse events with mipomersen. Mild-to-moderate flu-like symptoms were reported more often with mipomersen. Alanine transaminase increase, aspartate transaminase increase, and hepatic steatosis occurred in 21%, 13% and 13% of mipomersen treated patients, respectively. Adverse events by category for the placebo and mipomersen groups respectively were: total adverse events, 16(84.2%, 39(100%; serious adverse events, 0(0%, 6(15.4%; discontinuations due to adverse events, 1(5.3%, 8(20.5% and cardiac adverse events, 1(5.3%, 5(12.8%. CONCLUSION: Mipomersen significantly reduced LDL-C, apolipoprotein B, total cholesterol and non
Speers-Roesch, Ben; Lague, Sabine L; Farrell, Anthony P; Richards, Jeffrey G
2013-08-01
The ability to maintain stable cardiac function during environmental hypoxia exposure is crucial for hypoxia tolerance in animals and depends upon the maintenance of cardiac energy balance as well as the state of the heart's extracellular environment (e.g., availability of metabolic fuels). Hypoxic depression of plasma [non-esterified fatty acids] (NEFA), an important cardiac aerobic fuel, is a common response in many species of hypoxia-tolerant fishes, including tilapia. We tested the hypothesis that decreased plasma [NEFA] is important for maintaining stable cardiac function during and following hypoxia exposure, based on the premise that continued reliance upon cardiac fatty acid metabolism under such conditions could impair cardiac function. We examined the effect of severe hypoxia exposure (PO2 tilapia heart under conditions of routine (400 μmol L(-1)) and low (75 μmol L(-1)) [palmitate], which mimicked the in vivo levels of plasma [NEFA] found in normoxic and hypoxic tilapia, respectively. Under both concentrations of palmitate, the in situ tilapia heart showed exceptional hypoxic performance as a result of a high maximum glycolytic potential, confirming our previous results using a perfusate without fatty acids. We additionally provide evidence suggesting that non-contractile ATP demand is depressed in tilapia heart during hypoxia exposure. Cardiac performance during and following severe hypoxia exposure was unaffected by the level of palmitate. Thus, we conclude that hypoxic depression of plasma [NEFA] in fishes does not play a role in cardiac hypoxia tolerance.
Maximizing without difficulty: A modified maximizing scale and its correlates
Linda Lai
2010-01-01
This article presents several studies that replicate and extend previous research on maximizing. A modified scale for measuring individual maximizing tendency is introduced. The scale has adequate psychometric properties and reflects maximizers' aspirations for high standards and their preference for extensive alternative search, but not the decision difficulty aspect included in several previous studies. Based on this scale, maximizing is positively correlated with optimism, need for cogniti...
K B Athreya
2009-09-01
It is shown that (i) every probability density is the unique maximizer of relative entropy in an appropriate class and (ii) in the class of all pdf that satisfy $\\int fh_id_=_i$ for $i=1,2,\\ldots,\\ldots k$ the maximizer of entropy is an $f_0$ that is proportional to $\\exp(\\sum c_i h_i)$ for some choice of $c_i$. An extension of this to a continuum of constraints and many examples are presented.
Kaffarnik, Magnus F; Ahmadi, Navid; Lock, Johan F; Wuensch, Tilo; Pratschke, Johann; Stockmann, Martin; Malinowski, Maciej
2017-01-01
To investigate the relationship between the degree of liver dysfunction, quantified by maximal liver function capacity (LiMAx test) and endothelin-1, TNF-α and IL-6 in septic surgical patients. 28 septic patients (8 female, 20 male, age range 35-80y) were prospectively investigated on a surgical intensive care unit. Liver function, defined by LiMAx test, and measurements of plasma levels of endothelin-1, TNF-α and IL-6 were carried out within the first 24 hours after onset of septic symptoms, followed by day 2, 5 and 10. Patients were divided into 2 groups (group A: LiMAx ≥100 μg/kg/h, moderate liver dysfunction; group B: LiMAx <100 μg/kg/h, severe liver dysfunction) for analysis and investigated regarding the correlation between endothelin-1 and the severity of liver failure, quantified by LiMAx test. Group B showed significant higher results for endothelin-1 than patients in group A (P = 0.01, d5; 0.02, d10). For TNF-α, group B revealed higher results than group A, with a significant difference on day 10 (P = 0.005). IL-6 showed a non-significant trend to higher results in group B. The Spearman's rank correlation coefficient revealed a significant correlation between LiMAx and endothelin-1 (-0.434; P <0.001), TNF-α (-0.515; P <0.001) and IL-6 (-0.590; P <0.001). Sepsis-related hepatic dysfunction is associated with elevated plasma levels of endothelin-1, TNF-α and IL-6. Low LiMAx results combined with increased endothelin-1 and TNF-α and a favourable correlation between LiMAx and cytokine values support the findings of a crucial role of Endothelin-1 and TNF-α in development of septic liver failure.
On the maximal efficiency of the collisional Penrose process
Leiderschneider, Elly
2015-01-01
The center of mass (CM) energy in a collisional Penrose process - a collision taking place within the ergosphere of a Kerr black hole - can diverge under suitable extreme conditions (maximal Kerr, near horizon collision and suitable impact parameters). We present an analytic expression for the CM energy, refining expressions given in the literature. Even though the CM energy diverges, we show that the maximal energy attained by a particle that escapes the black hole's gravitational pull and reaches infinity is modest. We obtain an analytic expression for the energy of an escaping particle resulting from a collisional Penrose process, and apply it to derive the maximal energy and the maximal efficiency for several physical scenarios: pair annihilation, Compton scattering, and the elastic scattering of two massive particles. In all physically reasonable cases (in which the incident particles initially fall from infinity towards the black hole) the maximal energy (and the corresponding efficiency) are only one o...
Total Colors Maximal Cliques Chromatic Numbers of Several Classes of Graphs%若干图类的全色极大团色数
韩淑芹
2015-01-01
On the basis of the graph M(G) which is a Mycielski graph,a class of diagram Sm(G) that similar to the graph M(G) in structure were defined. The total colors maximal cliques chromatic numbers of the graph M(C3 ),a special sub-graph of graph M(G) and Sm(G) were obtained,where C3 represents 3 order circle.%在图 G 的 Mycielski 图 M(G)的基础上,定义了结构类似的一类图 Sm(G),研究了 M(C3),M(G)的一个特殊子图以及 Sm(G)的全色极大团染色,得到了相应的染色数,其中 C3表示3阶圈。
Yu Wanying; Zhang Hua; Huang Weidong; Chen Jiping; Liang Xinmiao
2006-01-01
Gas chromatography/quadrupole mass spectrometry (GC/qMS),gas chromatography/Fourier transform infrared spectrometry(CC/FTIR)and gas chromatography/orthogonal acceleration time-of-flight mass spectrometry(GC/oaTOFMS)were applied to analyze the volatile oil from the stem of Acanthopanax Senticosus(Rupr.et Maxim.)Harms.Based on the mass spectra search function of GC/qMS with the aid of the discriminability of the geometrical isomer by GC/FTIR and the ability to determine the accurate mass charge ratio(m/z)by GC/oaTOFMS,68 GC eluants were identified successfully.Compared with the results obtained by GC/qMS only,the analytical results obtained by these hyphenated methods of gas chromatography are more credible.
Maximizing without difficulty: A modified maximizing scale and its correlates
Lai, Linda
2010-01-01
... included in several previous studies. Based on this scale, maximizing is positively correlated with optimism, need for cognition, desire for consistency, risk aversion, intrinsic motivation, self-efficacy and perceived workload, whereas...
Combeau, H.; Appolaire, B. [Institut Jean Lamour, Departement SI2 M, CNRS - Nancy-Universite - UPV-Metz, Ecole des Mines de Nancy, Parc de Saurupt CS 14234, F-54042 Nancy Cedex (France); Seiler, J.M., E-mail: jean-marie.seiler@cea.f [CEA/DEN Grenoble, DTN/SE2T/LPTM, 17 rue des Martyrs, 38054 Grenoble Cedex 9 (France)
2010-08-15
T{sub liquidus} was proposed as the interface temperature, for various severe accident situations for thermalhydraulic steady state. This proposal was made on the basis of the analysis of solidification front stability in thermalhydraulic steady state for volumetrically heated corium pools and was extended to reactor transients with slow solidification rates that are controlled by the long-term decrease in residual power. The conclusions were corroborated by prototypic corium and variable solidification rates obtained by experimental approaches for corium containing small amounts of silica or none at all. When the concentration in silica increases (approximately above 10 wt%), it was concluded from the experiments that a plane-front situation could not be obtained. The present work offers a theoretical approach to the maximum time delay that is necessary for mass transfer and full phase-segregation in volumetrically heated liquid pools bounded by a crust. It is concluded that full segregation is obtained for in-vessel situations within time delays that are shorter or of the same order of magnitude as the characteristic time for the corium pool to form and evolve to a quasi-steady-state situation. The characteristic time delay for mass transfer associated with simulant material experiments is also determined. Phase segregation can also be obtained for corium-concrete interaction, provided that the silica content is less than approximately 10 wt%. However in the latter case, more complex phenomena occur at the interface due to the interaction with sparging gas (such as porous medium formation) which requires a different model approach.
Brandes, U; Gaertler, M; Goerke, R; Hoefer, M; Nikoloski, Z; Wagner, D
2006-01-01
Several algorithms have been proposed to compute partitions of networks into communities that score high on a graph clustering index called modularity. While publications on these algorithms typically contain experimental evaluations to emphasize the plausibility of results, none of these algorithms has been shown to actually compute optimal partitions. We here settle the unknown complexity status of modularity maximization by showing that the corresponding decision version is NP-complete in the strong sense. As a consequence, any efficient, i.e. polynomial-time, algorithm is only heuristic and yields suboptimal partitions on many instances.
All maximally entangling unitary operators
Cohen, Scott M. [Department of Physics, Duquesne University, Pittsburgh, Pennsylvania 15282 (United States); Department of Physics, Carnegie-Mellon University, Pittsburgh, Pennsylvania 15213 (United States)
2011-11-15
We characterize all maximally entangling bipartite unitary operators, acting on systems A and B of arbitrary finite dimensions d{sub A}{<=}d{sub B}, when ancillary systems are available to both parties. Several useful and interesting consequences of this characterization are discussed, including an understanding of why the entangling and disentangling capacities of a given (maximally entangling) unitary can differ and a proof that these capacities must be equal when d{sub A}=d{sub B}.
Profit maximization mitigates competition
Dierker, Egbert; Grodal, Birgit
1996-01-01
We consider oligopolistic markets in which the notion of shareholders' utility is well-defined and compare the Bertrand-Nash equilibria in case of utility maximization with those under the usual profit maximization hypothesis. Our main result states that profit maximization leads to less price...... competition than utility maximization. Since profit maximization tends to raise prices, it may be regarded as beneficial for the owners as a whole. Moreover, if profit maximization is a good proxy for utility maximization, then there is no need for a general equilibrium analysis that takes the distribution...... of profits among consumers fully into account and partial equilibrium analysis suffices...
Maximally incompatible quantum observables
Heinosaari, Teiko, E-mail: teiko.heinosaari@utu.fi [Turku Centre for Quantum Physics, Department of Physics and Astronomy, University of Turku, FI-20014 Turku (Finland); Schultz, Jussi, E-mail: jussi.schultz@gmail.com [Dipartimento di Matematica, Politecnico di Milano, Piazza Leonardo da Vinci 32, I-20133 Milano (Italy); Toigo, Alessandro, E-mail: alessandro.toigo@polimi.it [Dipartimento di Matematica, Politecnico di Milano, Piazza Leonardo da Vinci 32, I-20133 Milano (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Milano, Via Celoria 16, I-20133 Milano (Italy); Ziman, Mario, E-mail: ziman@savba.sk [RCQI, Institute of Physics, Slovak Academy of Sciences, Dúbravská cesta 9, 84511 Bratislava (Slovakia); Faculty of Informatics, Masaryk University, Botanická 68a, 60200 Brno (Czech Republic)
2014-05-01
The existence of maximally incompatible quantum observables in the sense of a minimal joint measurability region is investigated. Employing the universal quantum cloning device it is argued that only infinite dimensional quantum systems can accommodate maximal incompatibility. It is then shown that two of the most common pairs of complementary observables (position and momentum; number and phase) are maximally incompatible.
Parker, Andrew M.; Wandi Bruine de Bruin; Baruch Fischhoff
2007-01-01
Our previous research suggests that people reporting a stronger desire to maximize obtain worse life outcomes (Bruine de Bruin et al., 2007). Here, we examine whether this finding may be explained by the decision-making styles of self-reported maximizers. Expanding on Schwartz et al. (2002), we find that self-reported maximizers are more likely to show problematic decision-making styles, as evidenced by self-reports of less behavioral coping, greater dependence on others when making decisions...
U.S. Environmental Protection Agency — The Reach Address Database (RAD) stores the reach address of each Water Program feature that has been linked to the underlying surface water features (streams,...
Ming Yi WANG; Guo ZHAO
2005-01-01
A right R-module E over a ring R is said to be maximally injective in case for any maximal right ideal m of R, every R-homomorphism f : m → E can be extended to an R-homomorphism f' : R → E. In this paper, we first construct an example to show that maximal injectivity is a proper generalization of injectivity. Then we prove that any right R-module over a left perfect ring R is maximally injective if and only if it is injective. We also give a partial affirmative answer to Faith's conjecture by further investigating the property of maximally injective rings. Finally, we get an approximation to Faith's conjecture, which asserts that every injective right R-module over any left perfect right self-injective ring R is the injective hull of a projective submodule.
Andrew M. Parker
2007-12-01
Full Text Available Our previous research suggests that people reporting a stronger desire to maximize obtain worse life outcomes (Bruine de Bruin et al., 2007. Here, we examine whether this finding may be explained by the decision-making styles of self-reported maximizers. Expanding on Schwartz et al. (2002, we find that self-reported maximizers are more likely to show problematic decision-making styles, as evidenced by self-reports of less behavioral coping, greater dependence on others when making decisions, more avoidance of decision making, and greater tendency to experience regret. Contrary to predictions, self-reported maximizers were more likely to report spontaneous decision making. However, the relationship between self-reported maximizing and worse life outcomes is largely unaffected by controls for measures of other decision-making styles, decision-making competence, and demographic variables.
Brüstle, Thomas; Pérotin, Matthieu
2012-01-01
Maximal green sequences are particular sequences of quiver mutations which were introduced by Keller in the context of quantum dilogarithm identities and independently by Cecotti-Cordova-Vafa in the context of supersymmetric gauge theory. Our aim is to initiate a systematic study of these sequences from a combinatorial point of view. Interpreting maximal green sequences as paths in various natural posets arising in representation theory, we prove the finiteness of the number of maximal green sequences for cluster finite quivers, affine quivers and acyclic quivers with at most three vertices. We also give results concerning the possible numbers and lengths of these maximal green sequences. Finally we describe an algorithm for computing maximal green sequences for arbitrary valued quivers which we used to obtain numerous explicit examples that we present.
Are all maximally entangled states pure?
Cavalcanti, D; Terra-Cunha, M O
2005-01-01
In this Letter we study if all maximally entangled states are pure through several entanglement monotones. Our conclusions allow us to generalize the idea of monogamy of entanglement. Then we propose a polygamy of entanglement, which express that if a general multipartite state is maximally entangled it is necessarily factorized by any other system.
Rudiger Bubner
1998-12-01
Full Text Available Even though the maxims' theory is not at thecenter of Kant's ethics, it is the unavoidable basis of the categoric imperative's formulation. Kant leanson the transmitted representations of modem moral theory. During the last decades, the notion of maxims has deserved more attention, due to the philosophy of language's debates on rules, and due to action theory's interest in this notion. I here by brietly expound my views in these discussions.
2016-09-01
Popular culture reflects both the interests of and the issues affecting the general public. As concerns regarding climate change and its impacts grow, is it permeating into popular culture and reaching that global audience?
Teratology testing under REACH.
Barton, Steve
2013-01-01
REACH guidelines may require teratology testing for new and existing chemicals. This chapter discusses procedures to assess the need for teratology testing and the conduct and interpretation of teratology tests where required.
Reaching affects saccade trajectories.
Tipper, S P; Howard, L A; Paul, M A
2001-01-01
The pre-motor theory suggests that, when attention is oriented to a location, the motor systems that are involved in achieving current behavioural goals are activated. For example, when a task requires accurate reaching, attention to a location activates the motor circuits controlling saccades and manual reaches. These actions involve separate neural systems for the control of eye and hand, but we believe that the selection processes acting on neural population codes within these systems are similar and can affect each other. The attentional effect can be revealed in the subsequent movement. The present study shows that the path the eye takes as it saccades to a target is affected by whether a reach to the target is also produced. This effect is interpreted as the influence of a hand-centred frame used in reaching on the spatial frame of reference required for the saccade.
Maximal Hypersurfaces in Spacetimes with Translational Symmetry
Bulawa, Andrew
2016-01-01
We consider four-dimensional vacuum spacetimes which admit a free isometric spacelike R-action. Taking a quotient with respect to the R-action produces a three-dimensional quotient spacetime. We establish several results regarding maximal hypersurfaces (spacelike hypersurfaces of zero mean curvature) in quotient spacetimes. First, we show that complete noncompact maximal hypersurfaces must either be flat cylinders S^1 x R or conformal to the Euclidean plane. Second, we establish a positive mass theorem for certain maximal hypersurfaces. Finally, while it is meaningful to use a bounded lapse when adopting the maximal hypersurface gauge condition in the four-dimensional (asymptotically flat) setting, it is shown here that nontrivial quotient spacetimes admit the maximal hypersurface gauge only with an unbounded lapse.
Michael E Reichenheim
2001-02-01
hospitals. To determine the ideal cut-off point of weight-for-age (WFA, the following estimators are of interest: the proportion of false negatives (PFN, false positives (PFP and the percentage of total gain by time (ptg. Weight-for-height (WFH (cut-off point at -2 SDs is used as reference for establishing severe acute malnutrition. RESULTS: The magnitude of false negatives declines steadily until the 3rd WFA percentile (P3 and reaches zero close to P9. At this point, the PFP is around 0.4. The ptg decreases sharply up to P4, declining smoothly towards P10 thereafter (54.5%. CONCLUSIONS: The WFA P10 can be recommended for the screening phase. At this cut-off point, there is still efficiency whereas losses of true cases of severe acute malnutrition are minimized.
Are all maximally entangled states pure?
Cavalcanti, D.; Brandão, F. G. S. L.; Terra Cunha, M. O.
2005-10-01
We study if all maximally entangled states are pure through several entanglement monotones. In the bipartite case, we find that the same conditions which lead to the uniqueness of the entropy of entanglement as a measure of entanglement exclude the existence of maximally mixed entangled states. In the multipartite scenario, our conclusions allow us to generalize the idea of the monogamy of entanglement: we establish the polygamy of entanglement, expressing that if a general state is maximally entangled with respect to some kind of multipartite entanglement, then it is necessarily factorized of any other system.
Janusz Brzozowski
2014-05-01
Full Text Available The atoms of a regular language are non-empty intersections of complemented and uncomplemented quotients of the language. Tight upper bounds on the number of atoms of a language and on the quotient complexities of atoms are known. We introduce a new class of regular languages, called the maximally atomic languages, consisting of all languages meeting these bounds. We prove the following result: If L is a regular language of quotient complexity n and G is the subgroup of permutations in the transition semigroup T of the minimal DFA of L, then L is maximally atomic if and only if G is transitive on k-subsets of 1,...,n for 0 <= k <= n and T contains a transformation of rank n-1.
Andersen, Klaus Ejner
1985-01-01
Guinea pig maximization tests (GPMT) with chlorocresol were performed to ascertain whether the sensitization rate was affected by minor changes in the Freund's complete adjuvant (FCA) emulsion used. Three types of emulsion were evaluated: the oil phase was mixed with propylene glycol, saline with...... to the saline/oil emulsion. Placing of the challenge patches affected the response, as simultaneous chlorocresol challenge on the flank located 2 cm closer to the abdomen than the usual challenge site gave decreased reactions....
Terry, Dorothy Givens
2012-01-01
Dr. Mae Jemison is the world's first woman astronaut of color who continues to reach for the stars. Jemison was recently successful in leading a team that has secured a $500,000 federal grant to make interstellar space travel a reality. The Dorothy Jemison Foundation for Excellence (named after Jemison's mother) was selected in June by the Defense…
REACH. Air Conditioning Units.
Garrison, Joe; And Others
As a part of the REACH (Refrigeration, Electro-Mechanical, Air-Conditioning, Heating) electromechanical cluster, this student manual contains individualized instructional units in the area of air conditioning. The instructional units focus on air conditioning fundamentals, window air conditioning, system and installation, troubleshooting and…
REACH. Air Conditioning Units.
Garrison, Joe; And Others
As a part of the REACH (Refrigeration, Electro-Mechanical, Air-Conditioning, Heating) electromechanical cluster, this student manual contains individualized instructional units in the area of air conditioning. The instructional units focus on air conditioning fundamentals, window air conditioning, system and installation, troubleshooting and…
Reaching into Pictorial Spaces
Volcic, Robert; Vishwanath, Dhanraj; Domini, Fulvio
2014-02-01
While binocular viewing of 2D pictures generates an impression of 3D objects and space, viewing a picture monocularly through an aperture produces a more compelling impression of depth and the feeling that the objects are "out there", almost touchable. Here, we asked observers to actually reach into pictorial space under both binocular- and monocular-aperture viewing. Images of natural scenes were presented at different physical distances via a mirror-system and their retinal size was kept constant. Targets that observers had to reach for in physical space were marked on the image plane, but at different pictorial depths. We measured the 3D position of the index finger at the end of each reach-to-point movement. Observers found the task intuitive. Reaching responses varied as a function of both pictorial depth and physical distance. Under binocular viewing, responses were mainly modulated by the different physical distances. Instead, under monocular viewing, responses were modulated by the different pictorial depths. Importantly, individual variations over time were minor, that is, observers conformed to a consistent pictorial space. Monocular viewing of 2D pictures thus produces a compelling experience of an immersive space and tangible solid objects that can be easily explored through motor actions.
Snow, Rufus; And Others
As a part of the REACH (Refrigeration, Electro-Mechanical, Air-Conditioning, Heating) electromechanical cluster, this student manual contains individualized instructional units in the area of refrigeration. The instructional units focus on refrigeration fundamentals, tubing and pipe, refrigerants, troubleshooting, window air conditioning, and…
Terry, Dorothy Givens
2012-01-01
Dr. Mae Jemison is the world's first woman astronaut of color who continues to reach for the stars. Jemison was recently successful in leading a team that has secured a $500,000 federal grant to make interstellar space travel a reality. The Dorothy Jemison Foundation for Excellence (named after Jemison's mother) was selected in June by the Defense…
Zak, Michail
2008-01-01
A report discusses an algorithm for a new kind of dynamics based on a quantum- classical hybrid-quantum-inspired maximizer. The model is represented by a modified Madelung equation in which the quantum potential is replaced by different, specially chosen 'computational' potential. As a result, the dynamics attains both quantum and classical properties: it preserves superposition and entanglement of random solutions, while allowing one to measure its state variables, using classical methods. Such optimal combination of characteristics is a perfect match for quantum-inspired computing. As an application, an algorithm for global maximum of an arbitrary integrable function is proposed. The idea of the proposed algorithm is very simple: based upon the Quantum-inspired Maximizer (QIM), introduce a positive function to be maximized as the probability density to which the solution is attracted. Then the larger value of this function will have the higher probability to appear. Special attention is paid to simulation of integer programming and NP-complete problems. It is demonstrated that the problem of global maximum of an integrable function can be found in polynomial time by using the proposed quantum- classical hybrid. The result is extended to a constrained maximum with applications to integer programming and TSP (Traveling Salesman Problem).
Social group utility maximization
Gong, Xiaowen; Yang, Lei; Zhang, Junshan
2014-01-01
This SpringerBrief explains how to leverage mobile users' social relationships to improve the interactions of mobile devices in mobile networks. It develops a social group utility maximization (SGUM) framework that captures diverse social ties of mobile users and diverse physical coupling of mobile devices. Key topics include random access control, power control, spectrum access, and location privacy.This brief also investigates SGUM-based power control game and random access control game, for which it establishes the socially-aware Nash equilibrium (SNE). It then examines the critical SGUM-b
Solar Hydrogen Reaching Maturity
Rongé Jan
2015-09-01
Full Text Available Increasingly vast research efforts are devoted to the development of materials and processes for solar hydrogen production by light-driven dissociation of water into oxygen and hydrogen. Storage of solar energy in chemical bonds resolves the issues associated with the intermittent nature of sunlight, by decoupling energy generation and consumption. This paper investigates recent advances and prospects in solar hydrogen processes that are reaching market readiness. Future energy scenarios involving solar hydrogen are proposed and a case is made for systems producing hydrogen from water vapor present in air, supported by advanced modeling.
HEMI: Hyperedge Majority Influence Maximization
Gangal, Varun; Narayanam, Ramasuri
2016-01-01
In this work, we consider the problem of influence maximization on a hypergraph. We first extend the Independent Cascade (IC) model to hypergraphs, and prove that the traditional influence maximization problem remains submodular. We then present a variant of the influence maximization problem (HEMI) where one seeks to maximize the number of hyperedges, a majority of whose nodes are influenced. We prove that HEMI is non-submodular under the diffusion model proposed.
Andersen, Klaus Ejner
1985-01-01
Guinea pig maximization tests (GPMT) with chlorocresol were performed to ascertain whether the sensitization rate was affected by minor changes in the Freund's complete adjuvant (FCA) emulsion used. Three types of emulsion were evaluated: the oil phase was mixed with propylene glycol, saline...... with 30% (v/v) ethanol or saline, respectively. Relative viscosity was used as one measure of physical properties of the emulsion. Higher degrees of sensitization (but not rates) were obtained at the 48 h challenge reading with the oil/propylene glycol and oil/saline + ethanol emulsions compared...... to the saline/oil emulsion. Placing of the challenge patches affected the response, as simultaneous chlorocresol challenge on the flank located 2 cm closer to the abdomen than the usual challenge site gave decreased reactions....
Westar reaches critical crossroads
1992-06-01
Westar Mining Ltd. has applied for court protection until September 30, 1992 to gain time to draw up a final reorganization plan. The Companies' Creditors Arrangement Act is a federal statute that allows a business to restructure financially without having to declare bankruptcy. Normal trade terms with suppliers are usually maintained during this period. The company is struggling under the effects of falling coal prices, a high Canadian dollar and a high debt burden. Changes in work practices at the company's Balmer mine are a major part of the restructuring. An agreement must be reached with the United Mineworkers of America and other stakeholders or the Balmer mine will close permanently. Employees have been locked out since May 1, 1992 when union members rejected the company's final offer.
MAXIMS VIOLATIONS IN LITERARY WORK
Widya Hanum Sari Pertiwi
2015-12-01
Full Text Available This study was qualitative research action that focuses to find out the flouting of Gricean maxims and the functions of the flouting in the tales which are included in collection of children literature entitled My Giant Treasury of Stories and Rhymes. The objective of the study is generally to identify the violation of maxims of quantity, quality, relevance, and manner in the data sources and also to analyze the use of the flouting in the tales which are included in the book. Qualitative design using categorizing strategies, specifically coding strategy, was applied. Thus, the researcher as the instrument in this investigation was selecting the tales, reading them, and gathering every item which reflects the violation of Gricean maxims based on some conditions of flouting maxims. On the basis of the data analysis, it was found that the some utterances in the tales, both narration and conversation, flouting the four maxims of conversation, namely maxim of quality, maxim of quantity, maxim of relevance, and maxim of manner. The researcher has also found that the flouting of maxims has one basic function that is to encourage the readers’ imagination toward the tales. This one basic function is developed by six others functions: (1 generating specific situation, (2 developing the plot, (3 enlivening the characters’ utterance, (4 implicating message, (5 indirectly characterizing characters, and (6 creating ambiguous setting. Keywords: children literature, tales, flouting maxims
Speeded reaching movements around invisible obstacles.
Todd E Hudson
Full Text Available We analyze the problem of obstacle avoidance from a Bayesian decision-theoretic perspective using an experimental task in which reaches around a virtual obstacle were made toward targets on an upright monitor. Subjects received monetary rewards for touching the target and incurred losses for accidentally touching the intervening obstacle. The locations of target-obstacle pairs within the workspace were varied from trial to trial. We compared human performance to that of a Bayesian ideal movement planner (who chooses motor strategies maximizing expected gain using the Dominance Test employed in Hudson et al. (2007. The ideal movement planner suffers from the same sources of noise as the human, but selects movement plans that maximize expected gain in the presence of that noise. We find good agreement between the predictions of the model and actual performance in most but not all experimental conditions.
Reaching Fleming's dicrimination bound
Gruebl, Gebhard
2012-01-01
Any rule for identifying a quantum system's state within a set of two non-orthogonal pure states by a single measurement is flawed. It has a non-zero probability of either yielding the wrong result or leaving the query undecided. This also holds if the measurement of an observable $A$ is repeated on a finite sample of $n$ state copies. We formulate a state identification rule for such a sample. This rule's probability of giving the wrong result turns out to be bounded from above by $1/n\\delta_{A}^{2}$ with $\\delta_{A}=|_{1}-_{2}|/(\\Delta_{1}A+\\Delta_{2}A).$ A larger $\\delta_{A}$ results in a smaller upper bound. Yet, according to Fleming, $\\delta_{A}$ cannot exceed $\\tan\\theta$ with $\\theta\\in(0,\\pi/2) $ being the angle between the pure states under consideration. We demonstrate that there exist observables $A$ which reach the bound $\\tan\\theta$ and we determine all of them.
2001-01-01
The creation of the world's largest sandstone cavern, not a small feat! At the bottom, cave-in preventing steel mesh can be seen clinging to the top of the tunnel. The digging of UX-15, the cavern that will house ATLAS, reached the upper ceiling of LEP on October 10th. The breakthrough which took place nearly 100 metres underground occurred precisely on schedule and exactly as planned. But much caution was taken beforehand to make the LEP breakthrough clean and safe. To prevent the possibility of cave-ins in the side tunnels that will eventually be attached to the completed UX-15 cavern, reinforcing steel mesh was fixed into the walls with bolts. Obviously no people were allowed in the LEP tunnels below UX-15 as the breakthrough occurred. The area was completely evacuated and fences were put into place to keep all personnel out. However, while personnel were being kept out of the tunnels below, this has been anything but the case for the work taking place up above. With the creation of the world's largest...
Maximal respiratory pressures among adolescent swimmers.
Rocha Crispino Santos, M A; Pinto, M L; Couto Sant'Anna, C; Bernhoeft, M
2011-01-01
Maximal inspiratory pressures (MIP) and maximal expiratory pressures (MEP) are useful indices of respiratory muscle strength in athletes. The aims of this study were: to describe the strength of the respiratory muscles of Olympic junior swim team, at baseline and after a standard physical training; and to determine if there is a differential inspiratory and expiratory pressure response to the physical training. A cross-sectional study evaluated 28 international-level swimmers with ages ranging from 15 to 17 years, 19 (61 %) being males. At baseline, MIP was found to be lower in females (P = .001). The mean values reached by males and females were: MIP(cmH2O) = M: 100.4 (± 26.5)/F: 67.8 (± 23.2); MEP (cmH2O) = M: 87.4 (± 20.7)/F: 73.9 (± 17.3). After the physical training they reached: MIP (cmH2O) = M: 95.3 (± 30.3)/F: 71.8 (± 35.6); MEP (cmH2O) = M: 82.8 (± 26.2)/F: 70.4 (± 8.3). No differential pressure responses were observed in either males or females. These results suggest that swimmers can sustain the magnitude of the initial maximal pressures. Other studies should be developed to clarify if MIP and MEP could be used as a marker of an athlete's performance.
Swanepoel, Konrad J
2011-01-01
A subset of a normed space X is called equilateral if the distance between any two points is the same. Let m(X) be the smallest possible size of an equilateral subset of X maximal with respect to inclusion. We first observe that Petty's construction of a d-dimensional X of any finite dimension d >= 4 with m(X)=4 can be generalised to show that m(X\\oplus_1\\R)=4 for any X of dimension at least 2 which has a smooth point on its unit sphere. By a construction involving Hadamard matrices we then show that both m(\\ell_p) and m(\\ell_p^d) are finite and bounded above by a function of p, for all 1 1 such that m(X) <= d+1 for all d-dimensional X with Banach-Mazur distance less than c from \\ell_p^d. Using Brouwer's fixed-point theorem we show that m(X) <= d+1 for all d-\\dimensional X with Banach-Mazur distance less than 3/2 from \\ell_\\infty^d. A graph-theoretical argument furthermore shows that m(\\ell_\\infty^d)=d+1. The above results lead us to conjecture that m(X) <= 1+\\dim X.
Unified Maximally Natural Supersymmetry
Huang, Junwu
2016-01-01
Maximally Natural Supersymmetry, an unusual weak-scale supersymmetric extension of the Standard Model based upon the inherently higher-dimensional mechanism of Scherk-Schwarz supersymmetry breaking (SSSB), possesses remarkably good fine tuning given present LHC limits. Here we construct a version with precision $SU(2)_{\\rm L} \\times U(1)_{\\rm Y} $ unification: $\\sin^2 \\theta_W(M_Z) \\simeq 0.231$ is predicted to $\\pm 2\\%$ by unifying $SU(2)_{\\rm L} \\times U(1)_{\\rm Y} $ into a 5D $SU(3)_{\\rm EW}$ theory at a Kaluza-Klein scale of $1/R_5 \\sim 4.4\\,{\\rm TeV}$, where SSSB is simultaneously realised. Full unification with $SU(3)_{\\rm C}$ is accommodated by extending the 5D theory to a $N=4$ supersymmetric $SU(6)$ gauge theory on a 6D rectangular orbifold at $1/R_6 \\sim 40 \\,{\\rm TeV}$. TeV-scale states beyond the SM include exotic charged fermions implied by $SU(3)_{\\rm EW}$ with masses lighter than $\\sim 1.2\\,{\\rm TeV}$, and squarks in the mass range $1.4\\,{\\rm TeV} - 2.3\\,{\\rm TeV}$, providing distinct signature...
Gradient dynamics and entropy production maximization
Janečka, Adam
2016-01-01
Gradient dynamics describes irreversible evolution by means of a dissipation potential, which leads to several advantageous features like Maxwell--Onsager relations, distinguishing between thermodynamic forces and fluxes or geometrical interpretation of the dynamics. Entropy production maximization is a powerful tool for predicting constitutive relations in engineering. In this paper, both approaches are compared and their shortcomings and advantages are discussed.
Maximal temperature in a simple thermodynamical system
Dai, De-Chang
2016-01-01
Temperature in a simple thermodynamical system is not limited from above. It is also widely believed that it does not make sense talking about temperatures higher than the Planck temperature in the absence of the full theory of quantum gravity. Here, we demonstrate that there exist a maximal achievable temperature in a system where particles obey the laws of quantum mechanics and classical gravity before we reach the realm of quantum gravity. Namely, if two particles with a given center of mass energy come at the distance shorter than the Schwarzschild diameter apart, according to classical gravity they will form a black hole. It is possible to calculate that a simple thermodynamical system will be dominated by black holes at a critical temperature which is about three times lower than the Planck temperature. That represents the maximal achievable temperature in a simple thermodynamical system.
Carnot cycle at finite power: attainability of maximal efficiency.
Allahverdyan, Armen E; Hovhannisyan, Karen V; Melkikh, Alexey V; Gevorkian, Sasun G
2013-08-01
We want to understand whether and to what extent the maximal (Carnot) efficiency for heat engines can be reached at a finite power. To this end we generalize the Carnot cycle so that it is not restricted to slow processes. We show that for realistic (i.e., not purposefully designed) engine-bath interactions, the work-optimal engine performing the generalized cycle close to the maximal efficiency has a long cycle time and hence vanishing power. This aspect is shown to relate to the theory of computational complexity. A physical manifestation of the same effect is Levinthal's paradox in the protein folding problem. The resolution of this paradox for realistic proteins allows to construct engines that can extract at a finite power 40% of the maximally possible work reaching 90% of the maximal efficiency. For purposefully designed engine-bath interactions, the Carnot efficiency is achievable at a large power.
Maximal subgroups of finite groups
S. Srinivasan
1990-01-01
Full Text Available In finite groups maximal subgroups play a very important role. Results in the literature show that if the maximal subgroup has a very small index in the whole group then it influences the structure of the group itself. In this paper we study the case when the index of the maximal subgroups of the groups have a special type of relation with the Fitting subgroup of the group.
Finding Maximal Quasiperiodicities in Strings
Brodal, Gerth Stølting; Pedersen, Christian N. S.
2000-01-01
of length n in time O(n log n) and space O(n). Our algorithm uses the suffix tree as the fundamental data structure combined with efficient methods for merging and performing multiple searches in search trees. Besides finding all maximal quasiperiodic substrings, our algorithm also marks the nodes......Apostolico and Ehrenfeucht defined the notion of a maximal quasiperiodic substring and gave an algorithm that finds all maximal quasiperiodic substrings in a string of length n in time O(n log2 n). In this paper we give an algorithm that finds all maximal quasiperiodic substrings in a string...
Maximizing Entropy over Markov Processes
Biondi, Fabrizio; Legay, Axel; Nielsen, Bo Friis
2013-01-01
computation reduces to finding a model of a specification with highest entropy. Entropy maximization for probabilistic process specifications has not been studied before, even though it is well known in Bayesian inference for discrete distributions. We give a characterization of global entropy of a process...... as a reward function, a polynomial algorithm to verify the existence of an system maximizing entropy among those respecting a specification, a procedure for the maximization of reward functions over Interval Markov Chains and its application to synthesize an implementation maximizing entropy. We show how...
Maximizing entropy over Markov processes
Biondi, Fabrizio; Legay, Axel; Nielsen, Bo Friis
2014-01-01
computation reduces to finding a model of a specification with highest entropy. Entropy maximization for probabilistic process specifications has not been studied before, even though it is well known in Bayesian inference for discrete distributions. We give a characterization of global entropy of a process...... as a reward function, a polynomial algorithm to verify the existence of a system maximizing entropy among those respecting a specification, a procedure for the maximization of reward functions over Interval Markov Chains and its application to synthesize an implementation maximizing entropy. We show how...
Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes.
Burger, Alexa; Lindsay, Helen; Felker, Anastasia; Hess, Christopher; Anders, Carolin; Chiavacci, Elena; Zaugg, Jonas; Weber, Lukas M; Catena, Raul; Jinek, Martin; Robinson, Mark D; Mosimann, Christian
2016-06-01
CRISPR-Cas9 enables efficient sequence-specific mutagenesis for creating somatic or germline mutants of model organisms. Key constraints in vivo remain the expression and delivery of active Cas9-sgRNA ribonucleoprotein complexes (RNPs) with minimal toxicity, variable mutagenesis efficiencies depending on targeting sequence, and high mutation mosaicism. Here, we apply in vitro assembled, fluorescent Cas9-sgRNA RNPs in solubilizing salt solution to achieve maximal mutagenesis efficiency in zebrafish embryos. MiSeq-based sequence analysis of targeted loci in individual embryos using CrispRVariants, a customized software tool for mutagenesis quantification and visualization, reveals efficient bi-allelic mutagenesis that reaches saturation at several tested gene loci. Such virtually complete mutagenesis exposes loss-of-function phenotypes for candidate genes in somatic mutant embryos for subsequent generation of stable germline mutants. We further show that targeting of non-coding elements in gene regulatory regions using saturating mutagenesis uncovers functional control elements in transgenic reporters and endogenous genes in injected embryos. Our results establish that optimally solubilized, in vitro assembled fluorescent Cas9-sgRNA RNPs provide a reproducible reagent for direct and scalable loss-of-function studies and applications beyond zebrafish experiments that require maximal DNA cutting efficiency in vivo.
Gonzalez-Sanchez, Jon
2010-01-01
Let $w = w(x_1,..., x_n)$ be a word, i.e. an element of the free group $F =$ on $n$ generators $x_1,..., x_n$. The verbal subgroup $w(G)$ of a group $G$ is the subgroup generated by the set $\\{w (g_1,...,g_n)^{\\pm 1} | g_i \\in G, 1\\leq i\\leq n \\}$ of all $w$-values in $G$. We say that a (finite) group $G$ is $w$-maximal if $|G:w(G)|> |H:w(H)|$ for all proper subgroups $H$ of $G$ and that $G$ is hereditarily $w$-maximal if every subgroup of $G$ is $w$-maximal. In this text we study $w$-maximal and hereditarily $w$-maximal (finite) groups.
Maximizing and customer loyalty: Are maximizers less loyal?
Linda Lai
2011-06-01
Full Text Available Despite their efforts to choose the best of all available solutions, maximizers seem to be more inclined than satisficers to regret their choices and to experience post-decisional dissonance. Maximizers may therefore be expected to change their decisions more frequently and hence exhibit lower customer loyalty to providers of products and services compared to satisficers. Findings from the study reported here (N = 1978 support this prediction. Maximizers reported significantly higher intentions to switch to another service provider (television provider than satisficers. Maximizers' intentions to switch appear to be intensified and mediated by higher proneness to regret, increased desire to discuss relevant choices with others, higher levels of perceived knowledge of alternatives, and higher ego involvement in the end product, compared to satisficers. Opportunities for future research are suggested.
Are maximizers really unhappy? The measurement of maximizing tendency,
Dalia L. Diab
2008-06-01
Full Text Available Recent research suggesting that people who maximize are less happy than those who satisfice has received considerable fanfare. The current study investigates whether this conclusion reflects the construct itself or rather how it is measured. We developed an alternative measure of maximizing tendency that is theory-based, has good psychometric properties, and predicts behavioral outcomes. In contrast to the existing maximization measure, our new measure did not correlate with life (dissatisfaction, nor with most maladaptive personality and decision-making traits. We conclude that the interpretation of maximizers as unhappy may be due to poor measurement of the construct. We present a more reliable and valid measure for future researchers to use.
Principles of maximally classical and maximally realistic quantum mechanics
S M Roy
2002-08-01
Recently Auberson, Mahoux, Roy and Singh have proved a long standing conjecture of Roy and Singh: In 2-dimensional phase space, a maximally realistic quantum mechanics can have quantum probabilities of no more than + 1 complete commuting cets (CCS) of observables coexisting as marginals of one positive phase space density. Here I formulate a stationary principle which gives a nonperturbative deﬁnition of a maximally classical as well as maximally realistic phase space density. I show that the maximally classical trajectories are in fact exactly classical in the simple examples of coherent states and bound states of an oscillator and Gaussian free particle states. In contrast, it is known that the de Broglie–Bohm realistic theory gives highly nonclassical trajectories.
A Class of Maximal Functions with Oscillating Kernels
Ahmad AL-SALMAN
2007-01-01
The author studies the Lp mapping properties of a class of maximal functions that are related to oscillatory singular integral operators. Lp estimates, as well as the corresponding weighted estimates of such maximal functions, are obtained. Moreover, several applications of our results are highlighted.
Maximizing petrochemicals from refineries
Glover, B.; Foley, T.; Frey, S. [UOP, Des Plaines, IL (United States)
2007-07-01
New fuel quality requirements and high growth rates for petrochemicals are providing both challenges and opportunities for refineries. A key challenge in refineries today is to improve of the value of the products from the FCC unit. In particular, light FCC naphtha and LCO are prime candidates for improved utilization. Processing options have been developed focusing on new opportunities for these traditional fuel components. The Total Petrochemicals/UOP Olefin Cracking Process cracks C4-C8 olefins to produce propylene and ethylene. This process can be integrated into FCC units running at all severity levels to produce valuable light olefins while reducing the olefin content of the light FCC naphtha. Integration of the Olefin Cracking Process with an FCC unit can be accomplished to allow a range of operating modes which can accommodate changing demand for propylene, cracked naphtha and alkylate. Other processes developed by UOP allow for upgrading LCO into a range of products including petrochemical grade xylenes, benzene, high cetane diesel and low sulfur high octane gasoline. Various processing options are available which allow the products from LCO conversion to be adjusted based on the needs and opportunities of an individual refinery, as well as the external petrochemical demand cycles. This presentation will examine recent refining and petrochemical trends and highlight new process technologies that can be used to generate additional revenue from petrochemical production while addressing evolving clean fuel demands. (orig.)
Maximizing ROI with yield management
Neil Snyder
2001-01-01
.... the technology is based on the concept of yield management, which aims to sell the right product to the right customer at the right price and the right time therefore maximizing revenue, or yield...
Are CEOs Expected Utility Maximizers?
John List; Charles Mason
2009-01-01
Are individuals expected utility maximizers? This question represents much more than academic curiosity. In a normative sense, at stake are the fundamental underpinnings of the bulk of the last half-century's models of choice under uncertainty. From a positive perspective, the ubiquitous use of benefit-cost analysis across government agencies renders the expected utility maximization paradigm literally the only game in town. In this study, we advance the literature by exploring CEO's preferen...
Gaussian maximally multipartite entangled states
Facchi, Paolo; Lupo, Cosmo; Mancini, Stefano; Pascazio, Saverio
2009-01-01
We introduce the notion of maximally multipartite entangled states (MMES) in the context of Gaussian continuous variable quantum systems. These are bosonic multipartite states that are maximally entangled over all possible bipartitions of the system. By considering multimode Gaussian states with constrained energy, we show that perfect MMESs, which exhibit the maximum amount of bipartite entanglement for all bipartitions, only exist for systems containing n=2 or 3 modes. We further numerically investigate the structure of MMESs and their frustration for n <= 7.
Salvio, Alberto; Strumia, Alessandro; Urbano, Alfredo
2016-01-01
Motivated by the 750 GeV diphoton excess found at LHC, we compute the maximal width into $\\gamma\\gamma$ that a neutral scalar can acquire through a loop of charged fermions or scalars as function of the maximal scale at which the theory holds, taking into account vacuum (meta)stability bounds. We show how an extra gauge symmetry can qualitatively weaken such bounds, and explore collider probes and connections with Dark Matter.
Time of day has no effect on maximal aerobic and peak power
Sesboüé B
2011-08-01
Full Text Available N Bessot1,3, S Moussay1,2, B Dufour1,2, D Davenne1,2, B Sesboüé1,3, A Gauthier1,21Inserm, ERI27, Caen, France; 2University Caen, Caen, France; 3CHRU Caen, Explorations Fonctionnelles, Caen, FranceBackground: The aim of this study was to explore the effect of time of day on peak power reached during an exercise test and maximal aerobic power achieved when the subject reached maximal oxygen uptake.Methods: Fifteen male competitive endurance cyclists performed a standardized maximal incremental exercise test at 06:00 hours and 18:00 hours. The test began with a 5-minute warmup period at a workload of 150 W. The work rate was then increased by incremental steps of 30 W per minute until the respiratory exchange ratio reached 1.00. Thereafter, workload was increased in steps of 15 W per minute until exhaustion was reached.Results: No significant diurnal variation was detected in physiological parameters (maximal oxygen uptake and maximal heart rate or biomechanical parameters (maximal aerobic power, peak power.Conclusion: Circadian variations classically reported in competitive aerobic performances could be due to fluctuations in maximal aerobic endurance and/or improvement in gestural efficiency (pattern of muscle activity, effective force production, and kinematics.Keywords: chronobiology, maximal aerobic power, peak power, maximal oxygen uptake, maximal incremental test
A. Garmroodi Asil
2017-09-01
To further reduce the sulfur dioxide emission of the entire refining process, two scenarios of acid gas or air preheats are investigated when either of them is used simultaneously with the third enrichment scheme. The maximum overall sulfur recovery efficiency and highest combustion chamber temperature is slightly higher for acid gas preheats but air preheat is more favorable because it is more benign. To the best of our knowledge, optimization of the entire GTU + enrichment section and SRU processes has not been addressed previously.
Modularity maximization using completely positive programming
Yazdanparast, Sakineh; Havens, Timothy C.
2017-04-01
Community detection is one of the most prominent problems of social network analysis. In this paper, a novel method for Modularity Maximization (MM) for community detection is presented which exploits the Alternating Direction Augmented Lagrangian (ADAL) method for maximizing a generalized form of Newman's modularity function. We first transform Newman's modularity function into a quadratic program and then use Completely Positive Programming (CPP) to map the quadratic program to a linear program, which provides the globally optimal maximum modularity partition. In order to solve the proposed CPP problem, a closed form solution using the ADAL merged with a rank minimization approach is proposed. The performance of the proposed method is evaluated on several real-world data sets used for benchmarks community detection. Simulation results shows the proposed technique provides outstanding results in terms of modularity value for crisp partitions.
Algebraic curves of maximal cyclicity
Caubergh, Magdalena; Dumortier, Freddy
2006-01-01
The paper deals with analytic families of planar vector fields, studying methods to detect the cyclicity of a non-isolated closed orbit, i.e. the maximum number of limit cycles that can locally bifurcate from it. It is known that this multi-parameter problem can be reduced to a single-parameter one, in the sense that there exist analytic curves in parameter space along which the maximal cyclicity can be attained. In that case one speaks about a maximal cyclicity curve (mcc) in case only the number is considered and of a maximal multiplicity curve (mmc) in case the multiplicity is also taken into account. In view of obtaining efficient algorithms for detecting the cyclicity, we investigate whether such mcc or mmc can be algebraic or even linear depending on certain general properties of the families or of their associated Bautin ideal. In any case by well chosen examples we show that prudence is appropriate.
Balance between noise and information flow maximizes set complexity of network dynamics.
Tuomo Mäki-Marttunen
Full Text Available Boolean networks have been used as a discrete model for several biological systems, including metabolic and genetic regulatory networks. Due to their simplicity they offer a firm foundation for generic studies of physical systems. In this work we show, using a measure of context-dependent information, set complexity, that prior to reaching an attractor, random Boolean networks pass through a transient state characterized by high complexity. We justify this finding with a use of another measure of complexity, namely, the statistical complexity. We show that the networks can be tuned to the regime of maximal complexity by adding a suitable amount of noise to the deterministic Boolean dynamics. In fact, we show that for networks with Poisson degree distributions, all networks ranging from subcritical to slightly supercritical can be tuned with noise to reach maximal set complexity in their dynamics. For networks with a fixed number of inputs this is true for near-to-critical networks. This increase in complexity is obtained at the expense of disruption in information flow. For a large ensemble of networks showing maximal complexity, there exists a balance between noise and contracting dynamics in the state space. In networks that are close to critical the intrinsic noise required for the tuning is smaller and thus also has the smallest effect in terms of the information processing in the system. Our results suggest that the maximization of complexity near to the state transition might be a more general phenomenon in physical systems, and that noise present in a system may in fact be useful in retaining the system in a state with high information content.
Greene, Nicholas
2012-01-01
ABOUT THE BOOK Halo Reach is the latest installment, and goes back to Halo's roots in more ways than one. Set around one of the most frequently referenced events in the Haloverse-The Fall of Reach-Reach puts you in the shoes of Noble 6, an unnamed Spartan, fighting a doomed battle to save the planet. Dual-wielding's gone, health is back, and equipment now takes the form of different "classes," with different weapon loadouts and special abilities (such as sprinting, cloaking, or flight). If you're reading this guide, you're either new to the Halo franchise and looking to get a leg up on all
BOUNDEDNESS OF MAXIMAL SINGULAR INTEGRALS
CHEN JIECHENG; ZHU XIANGRONG
2005-01-01
The authors study the singular integrals under the Hormander condition and the measure not satisfying the doubling condition. At first, if the corresponding singular integral is bounded from L2 to itseff, it is proved that the maximal singu lar integral is bounded from L∞ to RBMO except that it is infinite μ-a.e. on Rd. A sufficient condition and a necessary condition such that the maximal singular integral is bounded from L2 to itself are also obtained. There is a small gap between the two conditions.
Lunar Probe Reaches Deep Space
2011-01-01
@@ China's second lunar probe, Chang'e-2, has reached an orbit 1.5 million kilometers from Earth for an additional mission of deep space exploration, the State Administration for Science, Technology and Industry for National Defense announced.
Maximal energy extraction under discrete diffusive exchange
Hay, M. J., E-mail: hay@princeton.edu [Department of Astrophysical Sciences, Princeton University, Princeton, New Jersey 08544 (United States); Schiff, J. [Department of Mathematics, Bar-Ilan University, Ramat Gan 52900 (Israel); Fisch, N. J. [Department of Astrophysical Sciences, Princeton University, Princeton, New Jersey 08544 (United States); Princeton Plasma Physics Laboratory, Princeton, New Jersey 08543 (United States)
2015-10-15
Waves propagating through a bounded plasma can rearrange the densities of states in the six-dimensional velocity-configuration phase space. Depending on the rearrangement, the wave energy can either increase or decrease, with the difference taken up by the total plasma energy. In the case where the rearrangement is diffusive, only certain plasma states can be reached. It turns out that the set of reachable states through such diffusive rearrangements has been described in very different contexts. Building upon those descriptions, and making use of the fact that the plasma energy is a linear functional of the state densities, the maximal extractable energy under diffusive rearrangement can then be addressed through linear programming.
Maximal energy extraction under discrete diffusive exchange
Hay, Michael J; Fisch, Nathaniel J
2015-01-01
Waves propagating through a bounded plasma can rearrange the densities of states in the six-dimensional velocity-configuration phase space. Depending on the rearrangement, the wave energy can either increase or decrease, with the difference taken up by the total plasma energy. In the case where the rearrangement is diffusive, only certain plasma states can be reached. It turns out that the set of reachable states through such diffusive rearrangements has been described in very different contexts. Building upon those descriptions, and making use of the fact that the plasma energy is a linear functional of the state densities, the maximal extractable energy under diffusive rearrangement can then be addressed through linear programming.
Computing Maximally Supersymmetric Scattering Amplitudes
Stankowicz, James Michael, Jr.
This dissertation reviews work in computing N = 4 super-Yang--Mills (sYM) and N = 8 maximally supersymmetric gravity (mSUGRA) scattering amplitudes in D = 4 spacetime dimensions in novel ways. After a brief introduction and overview in Ch. 1, the various techniques used to construct amplitudes in the remainder of the dissertation are discussed in Ch. 2. This includes several new concepts such as d log and pure integrand bases, as well as how to construct the amplitude using exactly one kinematic point where it vanishes. Also included in this chapter is an outline of the Mathematica package on shell diagrams and numerics.m (osdn) that was developed for the computations herein. The rest of the dissertation is devoted to explicit examples. In Ch. 3, the starting point is tree-level sYM amplitudes that have integral representations with residues that obey amplitude relations. These residues are shown to have corresponding residue numerators that allow a double copy prescription that results in mSUGRA residues. In Ch. 4, the two-loop four-point sYM amplitude is constructed in several ways, showcasing many of the techniques of Ch. 2; this includes an example of how to use osdn. The two-loop five-point amplitude is also presented in a pure integrand representation with comments on how it was constructed from one homogeneous cut of the amplitude. On-going work on the two-loop n-point amplitude is presented at the end of Ch. 4. In Ch. 5, the three-loop four-point amplitude is presented in the d log representation and in the pure integrand representation. In Ch. 6, there are several examples of four- through seven-loop planar diagrams that illustrate how considerations of the singularity structure of the amplitude underpin dual-conformal invariance. Taken with the previous examples, this is additional evidence that the structure known to exist in the planar sector extends to the full theory. At the end of this chapter is a proof that all mSUGRA amplitudes have a pole at
Extended-reach wells tap outlying reserves
Nazzal, G. (Eastman Teleco, Houston, TX (United States))
1993-03-01
Extended-reach drilling (ERD) is being used to exploit fields and reserves that are located far from existing platforms. Effective wellbore placement from fewer platforms can reduce development costs, maximize production and increase reserve recovery. Six wells drilled offshore in the US, North Sea and Australia illustrate how to get the most economic benefit from available infrastructure. These wells are divided into three categories by depth (shallow, medium and deep). Vertical depth of these wells range from 963 to 12,791 ft TVD and displacements range from 4,871 to 23,917 ft. Important factors for successful extended-reach drilling included: careful, comprehensive pre-planning; adequate cuttings removal in all sections; hole stability in long, exposed intervals; torque and drag modeling of drilling BHAs, casing and liners; buoyancy-assisted casing techniques where appropriate; critical modifications to drilling rig and top drive, for medium and deep ERD; modified power swivels for shallow operations; drill pipe rubbers or other casing protection during extended periods of drill string rotation; heavy-wall casting across anticipated high-wear areas; survey accuracy and frequency; sound drilling practices and creativity to accomplish goals and objectives. This paper reviews the case history of these sites and records planning and design procedures.
Understanding maximal repetitions in strings
Crochemore, Maxime
2008-01-01
The cornerstone of any algorithm computing all repetitions in a string of length n in O(n) time is the fact that the number of runs (or maximal repetitions) is O(n). We give a simple proof of this result. As a consequence of our approach, the stronger result concerning the linearity of the sum of exponents of all runs follows easily.
Maximizing results in reconstruction of cheek defects.
Mureau, Marc A M; Hofer, Stefan O P
2009-07-01
The face is exceedingly important, as it is the medium through which individuals interact with the rest of society. Reconstruction of cheek defects after trauma or surgery is a continuing challenge for surgeons who wish to reliably restore facial function and appearance. Important in aesthetic facial reconstruction are the aesthetic unit principles, by which the face can be divided in central facial units (nose, lips, eyelids) and peripheral facial units (cheeks, forehead, chin). This article summarizes established options for reconstruction of cheek defects and provides an overview of several modifications as well as tips and tricks to avoid complications and maximize aesthetic results.
The Gribov ambiguity for maximal abelian and center gauges in SU(2) lattice gauge theory
Stack, John D.; Tucker, William W
2001-03-01
We present results for the fundamental string tension in SU(2) lattice gauge theory after projection to maximal abelian and direct maximal center gauges. We generate 20 Gribov copies/configuration. Abelian and center projected string tensions slowly decrease as higher values of the gauge functionals are reached.
Note on maximal distance separable codes
YANG Jian-sheng; WANG De-xiu; JIN Qing-fang
2009-01-01
In this paper, the maximal length of maximal distance separable(MDS)codes is studied, and a new upper bound formula of the maximal length of MDS codes is obtained. Especially, the exact values of the maximal length of MDS codes in some parameters are given.
Maximization, learning, and economic behavior.
Erev, Ido; Roth, Alvin E
2014-07-22
The rationality assumption that underlies mainstream economic theory has proved to be a useful approximation, despite the fact that systematic violations to its predictions can be found. That is, the assumption of rational behavior is useful in understanding the ways in which many successful economic institutions function, although it is also true that actual human behavior falls systematically short of perfect rationality. We consider a possible explanation of this apparent inconsistency, suggesting that mechanisms that rest on the rationality assumption are likely to be successful when they create an environment in which the behavior they try to facilitate leads to the best payoff for all agents on average, and most of the time. Review of basic learning research suggests that, under these conditions, people quickly learn to maximize expected return. This review also shows that there are many situations in which experience does not increase maximization. In many cases, experience leads people to underweight rare events. In addition, the current paper suggests that it is convenient to distinguish between two behavioral approaches to improve economic analyses. The first, and more conventional approach among behavioral economists and psychologists interested in judgment and decision making, highlights violations of the rational model and proposes descriptive models that capture these violations. The second approach studies human learning to clarify the conditions under which people quickly learn to maximize expected return. The current review highlights one set of conditions of this type and shows how the understanding of these conditions can facilitate market design.
J. de Haan; W.P. Knulst
2000-01-01
Original title: Het bereik van de kunsten. The reach of the arts (Het bereik van de kunsten) is the fourth study in a series which periodically analyses the status of cultural participation, reading and use of other media. The series, Support for culture (Het culturele draagvlak) is sponsored by th
Symmetry and approximability of submodular maximization problems
Vondrak, Jan
2011-01-01
A number of recent results on optimization problems involving submodular functions have made use of the multilinear relaxation of the problem. These results hold typically in the value oracle model, where the objective function is accessible via a black box returning f(S) for a given S. We present a general approach to deriving inapproximability results in the value oracle model, based on the notion of symmetry gap. Our main result is that for any fixed instance that exhibits a certain symmetry gap in its multilinear relaxation, there is a naturally related class of instances for which a better approximation factor than the symmetry gap would require exponentially many oracle queries. This unifies several known hardness results for submodular maximization, and implies several new ones. In particular, we prove that there is no constant-factor approximation for the problem of maximizing a non-negative submodular function over the bases of a matroid. We also provide a closely matching approximation algorithm for...
González, Claudio D
2016-01-01
The objectives of this work were to investigate the frequency of severe asthma (SA) according to WHO definition and to compare SA patients' characteristics with those of non-severe asthma (NSA); secondly, to investigate the level of control reached throughout a period of regular treatment. Between 1-1-2005 and 12-31-2014, 471 medical records from patients with bronchial asthma assisted in Buenos Aires City were analyzed. SA frequency was 40.1% (189/471), being significantly higher among patients from the public health system (47.7%, 108/226 vs. 33%, 81/245, p = 0.001). SA patients were older than NSA ones (51.3 ± 17.4 vs. 42.6 ± 17.1 years, p = 0.000), presented longer time since onset of the disease (median 30 vs. 20 years, p = 0.000), lower educational levels (secondary level or higher 41.7% vs. 58.1%, p = 0.000), lower frequency of rhinitis (47% vs. 60.6%, p = 0.004), more severe levels of airway obstruction (FEV% 50.2 ± 13.7 vs. 77.7 ± 12.4, p = 0.000), more frequent antecedents of Near Fatal Asthma (11.1% vs. 2.8%, p = 0.000), higher levels of serum IgE (median of 410 vs. 279 UI/l, p = 0.01) and higher demand of systemic steroids requirements and hospitalizations (68.7% vs. 50.7%, p = 0.000 and 37.5% vs. 15.9%, p = 0.000, respectively). A 30.6% of SA patients (58/189) reached a follow-up period of 12 months, 13 (22.5%) of whom reached the controlled asthma level. The frequency of SA found seems to be considerable. Multicenter studies to investigate the levels of control reached by SA patients with access to proper treatment are recommended.
Maximizing production rates of the Linde Hampson machine
Maytal, B.-Z.
2006-01-01
In contrast to the ideal case of unlimited size recuperator, any real Linde-Hampson machine of finite size recuperator can be optimized to reach the extreme rates of performance. The group of cryocoolers sharing the same size recuperator is optimized in a closed form by determining the corresponding flow rate which maximizes its rate of cold production. For a similar group of liquefiers an optimal flow rate is derived to maximize the rate of production of liquid cryogen. The group of cryocoolers sharing a constant and given flow rate is optimized by shortening the recuperator for reaching a maximum compactness measured by the cooling power per unit size of the recuperator. The optimum conditions are developed for nitrogen and argon. The relevance of this analysis is discussed in the context of practice of fast cooldown Joule-Thomson cryocooling.
Freudenburg, William R.
2006-01-01
Rather than seeking ivory-tower isolation, members of the Rural Sociological Society have always been distinguished by a willingness to work with specialists from a broad range of disciplines, and to work on some of the world's most challenging problems. What is less commonly recognized is that the willingness to reach beyond disciplinary…
Asymptotics of robust utility maximization
Knispel, Thomas
2012-01-01
For a stochastic factor model we maximize the long-term growth rate of robust expected power utility with parameter $\\lambda\\in(0,1)$. Using duality methods the problem is reformulated as an infinite time horizon, risk-sensitive control problem. Our results characterize the optimal growth rate, an optimal long-term trading strategy and an asymptotic worst-case model in terms of an ergodic Bellman equation. With these results we propose a duality approach to a "robust large deviations" criterion for optimal long-term investment.
Multivariate residues and maximal unitarity
Søgaard, Mads; Zhang, Yang
2013-12-01
We extend the maximal unitarity method to amplitude contributions whose cuts define multidimensional algebraic varieties. The technique is valid to all orders and is explicitly demonstrated at three loops in gauge theories with any number of fermions and scalars in the adjoint representation. Deca-cuts realized by replacement of real slice integration contours by higher-dimensional tori encircling the global poles are used to factorize the planar triple box onto a product of trees. We apply computational algebraic geometry and multivariate complex analysis to derive unique projectors for all master integral coefficients and obtain compact analytic formulae in terms of tree-level data.
Beeping a Maximal Independent Set
Afek, Yehuda; Alon, Noga; Bar-Joseph, Ziv; Cornejo, Alejandro; Haeupler, Bernhard; Kuhn, Fabian
2012-01-01
We consider the problem of computing a maximal independent set (MIS) in an extremely harsh broadcast model that relies only on carrier sensing. The model consists of an anonymous broadcast network in which nodes have no knowledge about the topology of the network or even an upper bound on its size. Furthermore, it is assumed that an adversary chooses at which time slot each node wakes up. At each time slot a node can either beep, that is, emit a signal, or be silent. At a particular time slot...
Maximal Congruences on Some Semigroups
Jintana Sanwong; R.P. Sullivan
2007-01-01
In 1976 Howie proved that a finite congruence-free semigroup is a simple group if it has at least three elements but no zero elementInfinite congruence-free semigroups are far more complicated to describe, but some have been constructed using semigroups of transformations (for example, by Howie in 1981 and by Marques in 1983)Here, forcertain semigroups S of numbers and of transformations, we determine all congruences p on S such that S/p is congruence-free, that is, we describe all maximal congruences on such semigroups S.
Maximal muscular vascular conductances during whole body upright exercise in humans
Calbet, J A L; Jensen-Urstad, M; Van Hall, Gerrit;
2004-01-01
That muscular blood flow may reach 2.5 l kg(-1) min(-1) in the quadriceps muscle has led to the suggestion that muscular vascular conductance must be restrained during whole body exercise to avoid hypotension. The main aim of this study was to determine the maximal arm and leg muscle vascular...... conductances (VC) during leg and arm exercise, to find out if the maximal muscular vasodilatory response is restrained during maximal combined arm and leg exercise. Six Swedish elite cross-country skiers, age (mean +/-s.e.m.) 24 +/- 2 years, height 180 +/- 2 cm, weight 74 +/- 2 kg, and maximal oxygen uptake...
Knowledge discovery by accuracy maximization.
Cacciatore, Stefano; Luchinat, Claudio; Tenori, Leonardo
2014-04-01
Here we describe KODAMA (knowledge discovery by accuracy maximization), an unsupervised and semisupervised learning algorithm that performs feature extraction from noisy and high-dimensional data. Unlike other data mining methods, the peculiarity of KODAMA is that it is driven by an integrated procedure of cross-validation of the results. The discovery of a local manifold's topology is led by a classifier through a Monte Carlo procedure of maximization of cross-validated predictive accuracy. Briefly, our approach differs from previous methods in that it has an integrated procedure of validation of the results. In this way, the method ensures the highest robustness of the obtained solution. This robustness is demonstrated on experimental datasets of gene expression and metabolomics, where KODAMA compares favorably with other existing feature extraction methods. KODAMA is then applied to an astronomical dataset, revealing unexpected features. Interesting and not easily predictable features are also found in the analysis of the State of the Union speeches by American presidents: KODAMA reveals an abrupt linguistic transition sharply separating all post-Reagan from all pre-Reagan speeches. The transition occurs during Reagan's presidency and not from its beginning.
Inapproximability of maximal strip recovery
Jiang, Minghui
2009-01-01
In comparative genomic, the first step of sequence analysis is usually to decompose two or more genomes into syntenic blocks that are segments of homologous chromosomes. For the reliable recovery of syntenic blocks, noise and ambiguities in the genomic maps need to be removed first. Maximal Strip Recovery (MSR) is an optimization problem proposed by Zheng, Zhu, and Sankoff for reliably recovering syntenic blocks from genomic maps in the midst of noise and ambiguities. Given $d$ genomic maps as sequences of gene markers, the objective of \\msr{d} is to find $d$ subsequences, one subsequence of each genomic map, such that the total length of syntenic blocks in these subsequences is maximized. For any constant $d \\ge 2$, a polynomial-time 2d-approximation for \\msr{d} was previously known. In this paper, we show that for any $d \\ge 2$, \\msr{d} is APX-hard, even for the most basic version of the problem in which all gene markers are distinct and appear in positive orientation in each genomic map. Moreover, we provi...
Maximal right smooth extension chains
Huang, Yun Bao
2010-01-01
If $w=u\\alpha$ for $\\alpha\\in \\Sigma=\\{1,2\\}$ and $u\\in \\Sigma^*$, then $w$ is said to be a \\textit{simple right extension}of $u$ and denoted by $u\\prec w$. Let $k$ be a positive integer and $P^k(\\epsilon)$ denote the set of all $C^\\infty$-words of height $k$. Set $u_{1},\\,u_{2},..., u_{m}\\in P^{k}(\\epsilon)$, if $u_{1}\\prec u_{2}\\prec ...\\prec u_{m}$ and there is no element $v$ of $P^{k}(\\epsilon)$ such that $v\\prec u_{1}\\text{or} u_{m}\\prec v$, then $u_{1}\\prec u_{2}\\prec...\\prec u_{m}$ is said to be a \\textit{maximal right smooth extension (MRSE) chains}of height $k$. In this paper, we show that \\textit{MRSE} chains of height $k$ constitutes a partition of smooth words of height $k$ and give the formula of the number of \\textit{MRSE} chains of height $k$ for each positive integer $k$. Moreover, since there exist the minimal height $h_1$ and maximal height $h_2$ of smooth words of length $n$ for each positive integer $n$, we find that \\textit{MRSE} chains of heights $h_1-1$ and $h_2+1$ are good candidates t...
Clemente, Christofer J; Withers, Philip C; Thompson, Graham
2012-01-01
Studies of locomotor performance often link variation in morphology with ecology. While maximum sprint speed is a commonly used performance variable, the absolute limits for this performance trait are not completely understood. Absolute maximal speed has often been shown to increase linearly with body size, but several comparative studies covering a large range of body sizes suggest that maximal speed does not increase indefinitely with body mass but rather reaches an optimum after which speed declines. Because of the comparative nature of these studies, it is difficult to determine whether this decrease is due to biomechanical constraints on maximal speed or is a consequence of phylogenetic inertia or perhaps relaxed selection for lower maximal speed at large body size. To explore this issue, we have examined intraspecific variations in morphology, maximal sprint speed, and kinematics for the yellow-spotted monitor lizard Varanus panoptes, which varied in body mass from 0.09 to 5.75 kg. We show a curvilinear relationship between body size and absolute maximal sprint speed with an optimal body mass with respect to speed of 1.245 kg. This excludes the phylogenetic inertia hypothesis, because this effect should be absent intraspecifically, while supporting the biomechanical constraints hypothesis. The relaxed selection hypothesis cannot be excluded if there is a size-based behavioral shift intraspecifically, but the biomechanical constraints hypothesis is better supported from kinematic analyses. Kinematic measurements of hind limb movement suggest that the distance moved by the body during the stance phase may limit maximum speed. This limit is thought to be imposed by a decreased ability of the bones and muscles to support body mass for larger lizards.
Sampling hard to reach populations.
Faugier, J; Sargeant, M
1997-10-01
Studies on 'hidden populations', such as homeless people, prostitutes and drug addicts, raise a number of specific methodological questions usually absent from research involving known populations and less sensitive subjects. This paper examines the advantages and limitations of nonrandom methods of data collection such as snowball sampling. It reviews the currently available literature on sampling hard to reach populations and highlights the dearth of material currently available on this subject. The paper also assesses the potential for using these methods in nursing research. The sampling methodology used by Faugier (1996) in her study of prostitutes, HIV and drugs is used as a current example within this context.
How to reach library users who cannot reach libraries?
Dragana Ljuić
2002-01-01
Full Text Available The article discusses the ways of getting library activities closer to the individuals or groups of users who have difficulties to or cannot visit the library themselves. The author presents the services offered by the Maribor Public Library and discusses how one of the basic human rights – the right to the access of cultural goods, knowledge and information - is exercised also through library activities. By enabling access to library material and information, public libraries help to fulfill basic human rights and thus raise the quality of living in a social environment. The following forms of library activities are presented in the article: »distance library« – borrowing books at home, in hospital, station for the bibliobus for disabled users, »mobile collections« in the institutions where users, due to their age or illness, have difficulties in accessing or even cannot reach library materials and information by themselves.
The maximal D = 4 supergravities
Wit, Bernard de [Institute for Theoretical Physics and Spinoza Institute, Utrecht University, Postbus 80.195, NL-3508 TD Utrecht (Netherlands); Samtleben, Henning [Laboratoire de Physique, ENS Lyon, 46 allee d' Italie, F-69364 Lyon CEDEX 07 (France); Trigiante, Mario [Dept. of Physics, Politecnico di Torino, Corso Duca degli Abruzzi 24, I-10129 Turin (Italy)
2007-06-15
All maximal supergravities in four space-time dimensions are presented. The ungauged Lagrangians can be encoded in an E{sub 7(7)}-Sp(56; R)/GL(28) matrix associated with the freedom of performing electric/magnetic duality transformations. The gauging is defined in terms of an embedding tensor {theta} which encodes the subgroup of E{sub 7(7)} that is realized as a local invariance. This embedding tensor may imply the presence of magnetic charges which require corresponding dual gauge fields. The latter can be incorporated by using a recently proposed formulation that involves tensor gauge fields in the adjoint representation of E{sub 7(7)}. In this formulation the results take a universal form irrespective of the electric/magnetic duality basis. We present the general class of supersymmetric and gauge invariant Lagrangians and discuss a number of applications.
Maximizing profit using recommender systems
Das, Aparna; Ricketts, Daniel
2009-01-01
Traditional recommendation systems make recommendations based solely on the customer's past purchases, product ratings and demographic data without considering the profitability the items being recommended. In this work we study the question of how a vendor can directly incorporate the profitability of items into its recommender so as to maximize its expected profit while still providing accurate recommendations. Our approach uses the output of any traditional recommender system and adjust them according to item profitabilities. Our approach is parameterized so the vendor can control how much the recommendation incorporating profits can deviate from the traditional recommendation. We study our approach under two settings and show that it achieves approximately 22% more profit than traditional recommendations.
The maximal D=5 supergravities
de Wit, Bernard; Trigiante, M; Wit, Bernard de; Samtleben, Henning; Trigiante, Mario
2007-01-01
The general Lagrangian for maximal supergravity in five spacetime dimensions is presented with vector potentials in the \\bar{27} and tensor fields in the 27 representation of E_6. This novel tensor-vector system is subject to an intricate set of gauge transformations, describing 3(27-t) massless helicity degrees of freedom for the vector fields and 3t massive spin degrees of freedom for the tensor fields, where the (even) value of t depends on the gauging. The kinetic term of the tensor fields is accompanied by a unique Chern-Simons coupling which involves both vector and tensor fields. The Lagrangians are completely encoded in terms of the embedding tensor which defines the E_6 subgroup that is gauged by the vectors. The embedding tensor is subject to two constraints which ensure the consistency of the combined vector-tensor gauge transformations and the supersymmetry of the full Lagrangian. This new formulation encompasses all possible gaugings.
Constraint Propagation as Information Maximization
Abdallah, A Nait
2012-01-01
Dana Scott used the partial order among partial functions for his mathematical model of recursively defined functions. He interpreted the partial order as one of information content. In this paper we elaborate on Scott's suggestion of regarding computation as a process of information maximization by applying it to the solution of constraint satisfaction problems. Here the method of constraint propagation can be interpreted as decreasing uncertainty about the solution -- that is, as gain in information about the solution. As illustrative example we choose numerical constraint satisfaction problems to be solved by interval constraints. To facilitate this approach to constraint solving we formulate constraint satisfaction problems as formulas in predicate logic. This necessitates extending the usual semantics for predicate logic so that meaning is assigned not only to sentences but also to formulas with free variables.
Maurice Schiff
1995-03-01
Full Text Available The traditional literature derives optimum and revenue-maximizing export taxes within two-country models. with one exporter and one importer (Johnson 1950-51, Tower 1977. In reality, most products, including primary products. are exported by several countries. In this paper, we present a theory of trade taxes in a three-country framework. This enables us to deal with strategic interactions among exporting countries. We show that (i if one of the countries is a Stackelberg leader, both countries improve their welfare relative to Nash equilibrium, and in the symmetric case, the follower's welfare is higher than that of the leader; (ii the revenue-maximizing Nash tax is larger than the optimum tax for each country; and (iii welfare may be higher in the revenue-maximizing Nash equilibrium than in the welfare-maximizing Nash equilibrium, a result which cannot arise in two-country models. The traditional literature derives optimum and revenue-maximizing export taxes within two-country models. with one exporter and one importer (Johnson 1950-51, Tower 1977. In reality, most products, including primary products. are exported by several countries. In this paper, we present a theory of trade taxes in a three-country framework. This enables us to deal with strategic interactions among exporting countries. We show that (i if one of the countries is a Stackelberg leader, both countries improve their welfare relative to Nash equilibrium, and in the symmetric case, the follower's welfare is higher than that of the leader; (ii the revenue-maximizing Nash tax is larger than the optimum tax for each country; and (iii welfare may be higher in the revenue-maximizing Nash equilibrium than in the welfare-maximizing Nash equilibrium, a result which cannot arise in two-country models.
Reaching Diverse Audiences through NOAO Education Programs
Pompea, Stephen M.; Sparks, R. T.; Walker, C. E.
2009-01-01
NOAO education programs are designed to reach diverse audiences. Examples described in this poster include the Hands-On Optics Project nationwide, an extension of the Hands-On Optics program at Boys and Girls Clubs in Arizona and in Hawaii, a professional development program for Navajo and Hopi teachers, a number of programs for the Tohono O'odham Nation, and a project collecting and reviewing Spanish language astronomy materials. Additionally NOAO is also involved in several local outreach projects for diverse and underserved audiences.
MAXIMIZING THE BENEFITS OF ERP SYSTEMS
Paulo André da Conceição Menezes
2010-04-01
Full Text Available The ERP (Enterprise Resource Planning systems have been consolidated in companies with different sizes and sectors, allowing their real benefits to be definitively evaluated. In this study, several interactions have been studied in different phases, such as the strategic priorities and strategic planning defined as ERP Strategy; business processes review and the ERP selection in the pre-implementation phase, the project management and ERP adaptation in the implementation phase, as well as the ERP revision and integration efforts in the post-implementation phase. Through rigorous use of case study methodology, this research led to developing and to testing a framework for maximizing the benefits of the ERP systems, and seeks to contribute for the generation of ERP initiatives to optimize their performance.
MAXIMIZING THE BENEFITS OF ERP SYSTEMS
Paulo André Da Conceiçao Menezes
2010-04-01
Full Text Available The ERP (Enterprise Resource Planning systems have been consolidated in companies with different sizes and sectors, allowing their real benefits to be definitively evaluated. In this study, several interactions have been studied in different phases, such as the strategic priorities and strategic planning defined as ERP Strategy; business processes review and the ERP selection in the pre-implementation phase, the project management and ERP adaptation in the implementation phase, as well as the ERP revision and integration efforts in the post-implementation phase. Through rigorous use of case study methodology, this research led to developing and to testing a framework for maximizing the benefits of the ERP systems, and seeks to contribute for the generation of ERP initiatives to optimize their performance.
Reach Envelope of Human Extremities
YANG Jingzhou(杨景周); ZHANG Yunqing(张云清); CHEN Liping(陈立平); ABDEL-MALEK Karim
2004-01-01
Significant attention in recent years has been given to obtain a better understanding of human joint ranges, measurement, and functionality, especially in conjunction with commands issued by the central nervous system. While researchers have studied motor commands needed to drive a limb to follow a path trajectory, various computer algorithms have been reported that provide adequate analysis of limb modeling and motion. This paper uses a rigorous mathematical formulation to model human limbs, understand their reach envelope, delineate barriers therein where a trajectory becomes difficult to control, and help visualize these barriers. Workspaces of a typical forearm with 9 degrees of freedom, a typical finger modeled as a 4- degree-of-freedom system, and a lower extremity with 4 degrees of freedom are discussed. The results show that using the proposed formulation, joint limits play an important role in distinguishing the barriers.
Beeping a Maximal Independent Set
Afek, Yehuda; Bar-Joseph, Ziv; Cornejo, Alejandro; Haeupler, Bernhard; Kuhn, Fabian
2012-01-01
We consider the problem of computing a maximal independent set (MIS) in an extremely harsh broadcast model that relies only on carrier sensing. The model consists of an anonymous broadcast network in which nodes have no knowledge about the topology of the network or even an upper bound on its size. Furthermore, it is assumed that an adversary chooses at which time slot each node wakes up. At each time slot a node can either beep, that is, emit a signal, or be silent. At a particular time slot, beeping nodes receive no feedback, while silent nodes can only differentiate between none of its neighbors beeping, or at least one of its neighbors beeping. We start by proving a lower bound that shows that in this model, it is not possible to locally converge to an MIS in sub-polynomial time. We then study four different relaxations of the model which allow us to circumvent the lower bound and find an MIS in polylogarithmic time. First, we show that if a polynomial upper bound on the network size is known, it is possi...
Maximal switchability of centralized networks
Vakulenko, Sergei; Morozov, Ivan; Radulescu, Ovidiu
2016-08-01
We consider continuous time Hopfield-like recurrent networks as dynamical models for gene regulation and neural networks. We are interested in networks that contain n high-degree nodes preferably connected to a large number of N s weakly connected satellites, a property that we call n/N s -centrality. If the hub dynamics is slow, we obtain that the large time network dynamics is completely defined by the hub dynamics. Moreover, such networks are maximally flexible and switchable, in the sense that they can switch from a globally attractive rest state to any structurally stable dynamics when the response time of a special controller hub is changed. In particular, we show that a decrease of the controller hub response time can lead to a sharp variation in the network attractor structure: we can obtain a set of new local attractors, whose number can increase exponentially with N, the total number of nodes of the nework. These new attractors can be periodic or even chaotic. We provide an algorithm, which allows us to design networks with the desired switching properties, or to learn them from time series, by adjusting the interactions between hubs and satellites. Such switchable networks could be used as models for context dependent adaptation in functional genetics or as models for cognitive functions in neuroscience.
A Maximally Supersymmetric Kondo Model
Harrison, Sarah; Kachru, Shamit; Torroba, Gonzalo; /Stanford U., Phys. Dept. /SLAC
2012-02-17
We study the maximally supersymmetric Kondo model obtained by adding a fermionic impurity to N = 4 supersymmetric Yang-Mills theory. While the original Kondo problem describes a defect interacting with a free Fermi liquid of itinerant electrons, here the ambient theory is an interacting CFT, and this introduces qualitatively new features into the system. The model arises in string theory by considering the intersection of a stack of M D5-branes with a stack of N D3-branes, at a point in the D3 worldvolume. We analyze the theory holographically, and propose a dictionary between the Kondo problem and antisymmetric Wilson loops in N = 4 SYM. We perform an explicit calculation of the D5 fluctuations in the D3 geometry and determine the spectrum of defect operators. This establishes the stability of the Kondo fixed point together with its basic thermodynamic properties. Known supergravity solutions for Wilson loops allow us to go beyond the probe approximation: the D5s disappear and are replaced by three-form flux piercing a new topologically non-trivial S3 in the corrected geometry. This describes the Kondo model in terms of a geometric transition. A dual matrix model reflects the basic properties of the corrected gravity solution in its eigenvalue distribution.
Maximal exercise performance in patients with postcancer fatigue
Prinsen, H.; Hopman, M.T.E.; Zwarts, M.J.; Leer, J.W.H.; Heerschap, A.; Bleijenberg, G.; Laarhoven, H.W.M. van
2013-01-01
PURPOSE: The aim of this study is to examine whether physical fitness of severely fatigued and non-fatigued cancer survivors, as measured by maximal exercise performance, is different between both groups and, if so, whether this difference can be explained by differences in physical activity, self-e
How to Maximize Learning for Gifted Math Students
Chamberlin, Scott A.
2008-01-01
Having a gifted math or science student in the family or classroom is a fascination as well as a significant challenge and responsibility for many parents and teachers. In order to help maximize student learning, several questions need to be asked. What should be the role of technology? How well do traditional schools serve gifted students? What…
Neuromuscular fatigue after maximal exercise in patients with cystic fibrosis.
Vallier, J M; Gruet, M; Mely, L; Pensini, M; Brisswalter, J
2011-04-01
The aim of this study was to determine whether patients with cystic fibrosis (CF), despite their ventilatory limitation, would develop neuromuscular fatigue of quadriceps muscles following a maximal cycling exercise. Eleven adults with CF (age=26.8±6.9years; forced expiratory volume in 1s=54.1±12.8% predicted) and 11 age-matched healthy subjects performed a maximal incremental cycle test with respiratory gas exchange measurements. Maximal voluntary contraction (MVC) and electromyographic (EMG) activity of the vastus medialis muscle were recorded before and after exercise. Neural and contractile properties of the quadriceps were also investigated using femoral nerve electrical stimulation. Patients had lower exercise capacity, peak oxygen uptake and MVC than controls. MVC fell significantly postexercise in both groups (CF: -20±10%, controls: -19±6%; ppattern (-38.4±14.4%, -42.1±14.7% and -15±20.4%) but the statistical significance was not reached for the maximal rate of twitch torque relaxation. In conclusion, CF patients demonstrated lower limb fatigue following symptom-limited cycle exercise, which was comparable to that exhibited by healthy controls. This fatigue may be due to contractile impairments and not to transmission failure. Further studies should be conducted in a larger sample to confirm these preliminary results.
How Do Chinese Enterprises Look at REACH?
无
2007-01-01
@@ The new European REACH (Registration, Evaluation, Authorization of Chemicals) regulation has come into force. As soon as the REACH white paper was issued, Chinese enterprises started to research the possible impacts of REACH and prepare to cope with them. How then do these Chinese enterprises look at REACH? Following are views of some Chinese enterprises exporting chemical products to the European Union.
The reach of INO for atmospheric neutrino oscillation parameters
Thakore, Tarak; Ghosh, Anushree; Choubey, Sandhya; Dighe, Amol
2013-05-01
The India-based Neutrino Observatory (INO) will host a 50 kt magnetized iron calorimeter (ICAL@INO) for the study of atmospheric neutrinos. Using the detector resolutions and efficiencies obtained by the INO collaboration from a full-detector GEANT4-based simulation, we determine the reach of this experiment for the measurement of the atmospheric neutrino mixing parameters ( {sin^2 {θ_{23 }}and| {\\varDelta m_{32}^2} |} ) . We also explore the sensitivity of this experiment to the octant of θ 23, and its deviation from maximal mixing.
The Reach of INO for Atmospheric Neutrino Oscillation Parameters
Thakore, Tarak; Choubey, Sandhya; Dighe, Amol
2013-01-01
The India-based Neutrino Observatory (INO) will host a 50 kt magnetized iron calorimeter (ICAL@INO) for the study of atmospheric neutrinos. Using the detector resolutions and efficiencies obtained by the INO collaboration from a full-detector GEANT4-based simulation, we determine the reach of this experiment for the measurement of the atmospheric neutrino mixing parameters ($\\sin^2 \\theta_{23}$ and $|\\Delta m_{32}^2 |$). We also explore the sensitivity of this experiment to the deviation of $\\theta_{23}$ from maximal mixing, and its octant.
Adaptive maximal poisson-disk sampling on surfaces
Yan, Dongming
2012-01-01
In this paper, we study the generation of maximal Poisson-disk sets with varying radii on surfaces. Based on the concepts of power diagram and regular triangulation, we present a geometric analysis of gaps in such disk sets on surfaces, which is the key ingredient of the adaptive maximal Poisson-disk sampling framework. Moreover, we adapt the presented sampling framework for remeshing applications. Several novel and efficient operators are developed for improving the sampling/meshing quality over the state-of-theart. © 2012 ACM.
Maximally entangled mixed states for qubit-qutrit systems
Mendonça, Paulo E. M. F.; Marchiolli, Marcelo A.; Hedemann, Samuel R.
2017-02-01
We consider the problems of maximizing the entanglement negativity of X-form qubit-qutrit density matrices with (i) a fixed spectrum and (ii) a fixed purity. In the first case, the problem is solved in full generality whereas, in the latter, partial solutions are obtained by imposing extra spectral constraints such as rank deficiency and degeneracy, which enable a semidefinite programming treatment for the optimization problem at hand. Despite the technically motivated assumptions, we provide strong numerical evidence that threefold degenerate X states of purity P reach the highest entanglement negativity accessible to arbitrary qubit-qutrit density matrices of the same purity, hence characterizing a sparse family of likely qubit-qutrit maximally entangled mixed states.
Efficient Conservation in a Utility-Maximization Framework
Frank W. Davis
2006-06-01
Full Text Available Systematic planning for biodiversity conservation is being conducted at scales ranging from global to national to regional. The prevailing planning paradigm is to identify the minimum land allocations needed to reach specified conservation targets or maximize the amount of conservation accomplished under an area or budget constraint. We propose a more general formulation for setting conservation priorities that involves goal setting, assessing the current conservation system, developing a scenario of future biodiversity given the current conservation system, and allocating available conservation funds to alter that scenario so as to maximize future biodiversity. Under this new formulation for setting conservation priorities, the value of a site depends on resource quality, threats to resource quality, and costs. This planning approach is designed to support collaborative processes and negotiation among competing interest groups. We demonstrate these ideas with a case study of the Sierra Nevada bioregion of California.
Luoto, S; Hupli, M; Alaranta, H; Hurri, H
1996-12-01
It has been claimed that with the aid of isokinetic trunk strength measuring devices it is possible to distinguish true muscular weakness from submaximal effort in the test. This proposition is based on the presumption that in the isokinetic trunk strength test identical performances can only be reproduced by maximal effort. The purpose of this study was to investigate whether it is possible to distinguish maximal effort from submaximal with the aid of the coefficient of variation (CV) in an isokinetic trunk muscle strength test. The study group included 35 (21 male and 14 female) subjects of whom 12 were healthy, 10 had a mild low-back pain and 13 had a more severe chronic low-back pain. The subjects performed five consecutive bendings both with maximal (100%) and submaximal (50%) efforts at a speed of 90 degrees/second. In maximal effort only healthy subjects reached an average level of CV close to 10% both in extension and in flexion. In the chronic low-back pain group the average CV was close to 20%. The difference in CV was statistically significant (p < 0.05-0.02) between the healthy and the chronic low-back pain subjects. In the submaximal effort all health groups had a CV of approximately 20% or more and no significant differences were found. The group of slightly variable measurements (CV = 11-20%) was remarkably large in both the maximal and submaximal effort. The results suggest that an effort with a CV of 11-20% cannot be classified as definitely submaximal or maximal. When the CV is less than 10% the effort can be fairly certainly classified as maximal.
Maximal inequalities for demimartingales and their applications
WANG XueJun; HU ShuHe
2009-01-01
In this paper,we establish some maximal inequalities for demimartingales which generalize and improve the results of Christofides.The maximal inequalities for demimartingales are used as key inequalities to establish other results including Doob's type maximal inequality for demimartingales,strong laws of large numbers and growth rate for demimartingales and associated random variables.At last,we give an equivalent condition of uniform integrability for demisubmartingales.
Maximal inequalities for demimartingales and their applications
无
2009-01-01
In this paper, we establish some maximal inequalities for demimartingales which generalize and improve the results of Christofides. The maximal inequalities for demimartingales are used as key inequalities to establish other results including Doob’s type maximal inequality for demimartingales, strong laws of large numbers and growth rate for demimartingales and associated random variables. At last, we give an equivalent condition of uniform integrability for demisubmartingales.
Long Maximal Incremental Tests Accurately Assess Aerobic Fitness in Class II and III Obese Men
Lanzi, Stefano; Codecasa, Franco; Cornacchia, Mauro; Maestrini, Sabrina; Capodaglio, Paolo; Brunani, Amelia; Fanari, Paolo; Salvadori, Alberto; Malatesta, Davide
2015-01-01
This study aimed to compare two different maximal incremental tests with different time durations [a maximal incremental ramp test with a short time duration (8-12 min) (STest) and a maximal incremental test with a longer time duration (20-25 min) (LTest)] to investigate whether an LTest accurately assesses aerobic fitness in class II and III obese men. Twenty obese men (BMI≥35 kg.m-2) without secondary pathologies (mean±SE; 36.7±1.9 yr; 41.8±0.7 kg*m-2) completed an STest (warm-up: 40 W; increment: 20 W*min-1) and an LTest [warm-up: 20% of the peak power output (PPO) reached during the STest; increment: 10% PPO every 5 min until 70% PPO was reached or until the respiratory exchange ratio reached 1.0, followed by 15 W.min-1 until exhaustion] on a cycle-ergometer to assess the peak oxygen uptake V˙O2peak and peak heart rate (HRpeak) of each test. There were no significant differences in V˙O2peak (STest: 3.1±0.1 L*min-1; LTest: 3.0±0.1 L*min-1) and HRpeak (STest: 174±4 bpm; LTest: 173±4 bpm) between the two tests. Bland-Altman plot analyses showed good agreement and Pearson product-moment and intra-class correlation coefficients showed a strong correlation between V˙O2peak (r=0.81 for both; p≤0.001) and HRpeak (r=0.95 for both; p≤0.001) during both tests. V˙O2peak and HRpeak assessments were not compromised by test duration in class II and III obese men. Therefore, we suggest that the LTest is a feasible test that accurately assesses aerobic fitness and may allow for the exercise intensity prescription and individualization that will lead to improved therapeutic approaches in treating obesity and severe obesity. PMID:25875746
Long maximal incremental tests accurately assess aerobic fitness in class II and III obese men.
Lanzi, Stefano; Codecasa, Franco; Cornacchia, Mauro; Maestrini, Sabrina; Capodaglio, Paolo; Brunani, Amelia; Fanari, Paolo; Salvadori, Alberto; Malatesta, Davide
2015-01-01
This study aimed to compare two different maximal incremental tests with different time durations [a maximal incremental ramp test with a short time duration (8-12 min) (STest) and a maximal incremental test with a longer time duration (20-25 min) (LTest)] to investigate whether an LTest accurately assesses aerobic fitness in class II and III obese men. Twenty obese men (BMI≥35 kg.m-2) without secondary pathologies (mean±SE; 36.7±1.9 yr; 41.8±0.7 kg*m-2) completed an STest (warm-up: 40 W; increment: 20 W*min-1) and an LTest [warm-up: 20% of the peak power output (PPO) reached during the STest; increment: 10% PPO every 5 min until 70% PPO was reached or until the respiratory exchange ratio reached 1.0, followed by 15 W.min-1 until exhaustion] on a cycle-ergometer to assess the peak oxygen uptake [Formula: see text] and peak heart rate (HRpeak) of each test. There were no significant differences in [Formula: see text] (STest: 3.1±0.1 L*min-1; LTest: 3.0±0.1 L*min-1) and HRpeak (STest: 174±4 bpm; LTest: 173±4 bpm) between the two tests. Bland-Altman plot analyses showed good agreement and Pearson product-moment and intra-class correlation coefficients showed a strong correlation between [Formula: see text] (r=0.81 for both; p≤0.001) and HRpeak (r=0.95 for both; p≤0.001) during both tests. [Formula: see text] and HRpeak assessments were not compromised by test duration in class II and III obese men. Therefore, we suggest that the LTest is a feasible test that accurately assesses aerobic fitness and may allow for the exercise intensity prescription and individualization that will lead to improved therapeutic approaches in treating obesity and severe obesity.
Long maximal incremental tests accurately assess aerobic fitness in class II and III obese men.
Stefano Lanzi
Full Text Available This study aimed to compare two different maximal incremental tests with different time durations [a maximal incremental ramp test with a short time duration (8-12 min (STest and a maximal incremental test with a longer time duration (20-25 min (LTest] to investigate whether an LTest accurately assesses aerobic fitness in class II and III obese men. Twenty obese men (BMI≥35 kg.m-2 without secondary pathologies (mean±SE; 36.7±1.9 yr; 41.8±0.7 kg*m-2 completed an STest (warm-up: 40 W; increment: 20 W*min-1 and an LTest [warm-up: 20% of the peak power output (PPO reached during the STest; increment: 10% PPO every 5 min until 70% PPO was reached or until the respiratory exchange ratio reached 1.0, followed by 15 W.min-1 until exhaustion] on a cycle-ergometer to assess the peak oxygen uptake [Formula: see text] and peak heart rate (HRpeak of each test. There were no significant differences in [Formula: see text] (STest: 3.1±0.1 L*min-1; LTest: 3.0±0.1 L*min-1 and HRpeak (STest: 174±4 bpm; LTest: 173±4 bpm between the two tests. Bland-Altman plot analyses showed good agreement and Pearson product-moment and intra-class correlation coefficients showed a strong correlation between [Formula: see text] (r=0.81 for both; p≤0.001 and HRpeak (r=0.95 for both; p≤0.001 during both tests. [Formula: see text] and HRpeak assessments were not compromised by test duration in class II and III obese men. Therefore, we suggest that the LTest is a feasible test that accurately assesses aerobic fitness and may allow for the exercise intensity prescription and individualization that will lead to improved therapeutic approaches in treating obesity and severe obesity.
Task-oriented maximally entangled states
Agrawal, Pankaj; Pradhan, B, E-mail: agrawal@iopb.res.i, E-mail: bpradhan@iopb.res.i [Institute of Physics, Sachivalaya Marg, Bhubaneswar, Orissa 751 005 (India)
2010-06-11
We introduce the notion of a task-oriented maximally entangled state (TMES). This notion depends on the task for which a quantum state is used as the resource. TMESs are the states that can be used to carry out the task maximally. This concept may be more useful than that of a general maximally entangled state in the case of a multipartite system. We illustrate this idea by giving an operational definition of maximally entangled states on the basis of communication tasks of teleportation and superdense coding. We also give examples and a procedure to obtain such TMESs for n-qubit systems.
Inflation in maximal gauged supergravities
Kodama, Hideo [Theory Center, KEK,Tsukuba 305-0801 (Japan); Department of Particles and Nuclear Physics,The Graduate University for Advanced Studies,Tsukuba 305-0801 (Japan); Nozawa, Masato [Dipartimento di Fisica, Università di Milano, and INFN, Sezione di Milano,Via Celoria 16, 20133 Milano (Italy)
2015-05-18
We discuss the dynamics of multiple scalar fields and the possibility of realistic inflation in the maximal gauged supergravity. In this paper, we address this problem in the framework of recently discovered 1-parameter deformation of SO(4,4) and SO(5,3) dyonic gaugings, for which the base point of the scalar manifold corresponds to an unstable de Sitter critical point. In the gauge-field frame where the embedding tensor takes the value in the sum of the 36 and 36’ representations of SL(8), we present a scheme that allows us to derive an analytic expression for the scalar potential. With the help of this formalism, we derive the full potential and gauge coupling functions in analytic forms for the SO(3)×SO(3)-invariant subsectors of SO(4,4) and SO(5,3) gaugings, and argue that there exist no new critical points in addition to those discovered so far. For the SO(4,4) gauging, we also study the behavior of 6-dimensional scalar fields in this sector near the Dall’Agata-Inverso de Sitter critical point at which the negative eigenvalue of the scalar mass square with the largest modulus goes to zero as the deformation parameter s approaches a critical value s{sub c}. We find that when the deformation parameter s is taken sufficiently close to the critical value, inflation lasts more than 60 e-folds even if the initial point of the inflaton allows an O(0.1) deviation in Planck units from the Dall’Agata-Inverso critical point. It turns out that the spectral index n{sub s} of the curvature perturbation at the time of the 60 e-folding number is always about 0.96 and within the 1σ range n{sub s}=0.9639±0.0047 obtained by Planck, irrespective of the value of the η parameter at the critical saddle point. The tensor-scalar ratio predicted by this model is around 10{sup −3} and is close to the value in the Starobinsky model.
Can donated media placements reach intended audiences?
Cooper, Crystale Purvis; Gelb, Cynthia A; Chu, Jennifer; Polonec, Lindsey
2013-09-01
Donated media placements for public service announcements (PSAs) can be difficult to secure, and may not always reach intended audiences. Strategies used by the Centers for Disease Control and Prevention's (CDC) Screen for Life: National Colorectal Cancer Action Campaign (SFL) to obtain donated media placements include producing a diverse mix of high-quality PSAs, co-branding with state and tribal health agencies, securing celebrity involvement, monitoring media trends to identify new distribution opportunities, and strategically timing the release of PSAs. To investigate open-ended recall of PSAs promoting colorectal cancer screening, CDC conducted 12 focus groups in three U.S. cities with men and women either nearing age 50 years, when screening is recommended to begin, or aged 50-75 years who were not in compliance with screening guidelines. In most focus groups, multiple participants recalled exposure to PSAs promoting colorectal cancer screening, and most of these individuals reported having seen SFL PSAs on television, in transit stations, or on the sides of public buses. Some participants reported exposure to SFL PSAs without prompting from the moderator, as they explained how they learned about the disease. Several participants reported learning key campaign messages from PSAs, including that colorectal cancer screening should begin at age 50 years and screening can find polyps so they can be removed before becoming cancerous. Donated media placements can reach and educate mass audiences, including millions of U.S. adults who have not been screened appropriately for colorectal cancer.
Reach Scale Sediment Balance of Goodwin Creek Watershed, Mississippi
Ran, L.; Garcia, T.; Ye, S.; Harman, C. J.; Hassan, M. A.; Simon, A.
2010-12-01
Several reaches of Goodwin Creek, an experimental watershed within the Mississippi river basin, were analyzed for the period 1977-2007 in terms of long-term trends in sediment gain and loss in each reach, the relation of input and output to within-reach sediment fluxes, and the impacts of land use and bank erosion on reach sediment dynamics. Over the period 1977-2007, degradational and aggradational reaches were identified indicating slight vertical adjustment along the mainstream. Lateral adjustment was the main response of the channel to changes in flow and sediment regimes. Event-based sediment load was estimated using suspended concentration data, bedload transport rate, and changes in cross-sectional data. Bank erosion was estimated using cross-sectional data and models. The spatial and temporal patterns of within-reach sediment dynamics correspond closely with river morphology and also reflect basin conditions over the last three decades; thus they are conditioned by coeval trends in climate, hydrology, and land use. The sediment exchange within the mainstream was calculated by the development of reach sediment balances that reveal complex spatial and temporal patterns of sediment dynamics. Sediment load during the rising limb of the hydrograph was slightly higher than those estimated for the falling limb indicating the relative importance of sediment supply on reach sediment dynamic in the basin. Cumulative plots of sediment exchange reveal that major changes in within reach sediment storage are associated with large floods or major inputs from bank erosion.
Priority setting in the REACH system.
Hansson, Sven Ove; Rudén, Christina
2006-04-01
Due to the large number of chemicals for which toxicological and ecotoxicological information is lacking, priority setting for data acquisition is a major concern in chemicals regulation. In the current European system, two administrative priority-setting criteria are used, namely novelty (i.e., time of market introduction) and production volume. In the proposed Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) system, the novelty criterion is no longer used, and production volume will be the main priority-setting criterion for testing requirements, supplemented in some cases with hazard indications obtained from QSAR modelling. This system for priority setting has severe weaknesses. In this paper we propose that a multicriteria system should be developed that includes at least three additional criteria: chemical properties, results from initial testing in a tiered system, and voluntary testing for which efficient incentives can be created. Toxicological and decision-theoretical research is needed to design testing systems with validated priority-setting mechanisms.
ALMA telescope reaches new heights
2009-09-01
of the Array Operations Site. This means surviving strong winds and temperatures between +20 and -20 Celsius whilst being able to point precisely enough that they could pick out a golf ball at a distance of 15 km, and to keep their smooth reflecting surfaces accurate to better than 25 micrometres (less than the typical thickness of a human hair). Once the transporter reached the high plateau it carried the antenna to a concrete pad - a docking station with connections for power and fibre optics - and positioned it with an accuracy of a few millimetres. The transporter is guided by a laser steering system and, just like some cars today, also has ultrasonic collision detectors. These sensors ensure the safety of the state-of-the-art antennas as the transporter drives them across what will soon be a rather crowded plateau. Ultimately, ALMA will have at least 66 antennas distributed over about 200 pads, spread over distances of up to 18.5 km and operating as a single, giant telescope. Even when ALMA is fully operational, the transporters will be used to move the antennas between pads to reconfigure the telescope for different kinds of observations. "Transporting our first antenna to the Chajnantor plateau is a epic feat which exemplifies the exciting times in which ALMA is living. Day after day, our global collaboration brings us closer to the birth of the most ambitious ground-based astronomical observatory in the world", said Thijs de Graauw, ALMA Director. This first ALMA antenna at the high site will soon be joined by others and the ALMA team looks forward to making their first observations from the Chajnantor plateau. They plan to link three antennas by early 2010, and to make the first scientific observations with ALMA in the second half of 2011. ALMA will help astronomers answer important questions about our cosmic origins. The telescope will observe the Universe using light with millimetre and submillimetre wavelengths, between infrared light and radio waves in
[Treatment of severe scoliosis].
Helenius, Ilkka; Pajulo, Olli
2015-01-01
Untreated severe scoliosis results in a serious malposition of the back, restrictive lung disease and increases mortality compared with the normal population. Idiopathic scoliosis rarely reaches a severe degree. In the treatment of severe scoliosis, preoperative head traction of several weeks' duration has proven a safe and effective method of correcting the malposition, and will also make scoliosis surgery technically easier. Most cases of severe scoliosis can be treated with anterior pedicle screw instrumentation, and vertebrectomy is only seldom required.
Sampling and Representation Complexity of Revenue Maximization
Dughmi, Shaddin; Han, Li; Nisan, Noam
2014-01-01
We consider (approximate) revenue maximization in auctions where the distribution on input valuations is given via "black box" access to samples from the distribution. We observe that the number of samples required -- the sample complexity -- is tightly related to the representation complexity of an approximately revenue-maximizing auction. Our main results are upper bounds and an exponential lower bound on these complexities.
Lisonek, Petr
1996-01-01
our classifications confirmthe maximality of previously known sets, the results in E^7 and E^8are new. Their counterpart in dimension larger than 10is a set of unit vectors with only two values of inner products in the Lorentz space R^{d,1}.The maximality of this set again follows from a bound due...
An ethical justification of profit maximization
Koch, Carsten Allan
2010-01-01
In much of the literature on business ethics and corporate social responsibility, it is more or less taken for granted that attempts to maximize profits are inherently unethical. The purpose of this paper is to investigate whether an ethical argument can be given in support of profit maximizing b...
Alternative trailer configurations for maximizing payloads
Jason D. Thompson; Dana Mitchell; John Klepac
2017-01-01
In order for harvesting contractors to stay ahead of increasing costs, it is imperative that they employ all options to maximize productivity and efficiency. Transportation can account for half the cost to deliver wood to a mill. Contractors seek to maximize truck payload to increase productivity. The Forest Operations Research Unit, Southern Research Station, USDA...
Cohomology of Weakly Reducible Maximal Triangular Algebras
董浙; 鲁世杰
2000-01-01
In this paper, we introduce the concept of weakly reducible maximal triangular algebras φwhich form a large class of maximal triangular algebras. Let B be a weakly closed algebra containing 5φ, we prove that the cohomology spaces Hn(φ, B) (n≥1) are trivial.
Impact of Redd Loss at Vernita Bar on Hanford Reach Chinook Salmon Production: Final Report 1988.
Rogers, Donald E.
1988-10-01
This report describes the effect on chinook salmon production within the Hanford Reach of redd loss at Vernita Bar. The current target escapement of 40,000 chinook past McNary dam has no real biological justification because the wrong data were used in the analysis and the methods used are now known to be very unreliable for the type of data available. The escapement that maximizes MSY may be lower than 40,000, or much higher, and reliable estimates of optimum escapement are unlikely to be available for several more years. If the optimum escapement is truly 40,000 (or less), then loss of a few hundred redds on Vernita Bar would have no detrimental, and possibly beneficial consequences on total chinook production from the Hanford Reach, so long as escapements are in excess of 40,000. If the optimal escapement is actually much higher (60,000+), the biological cost of redd loss when escapements are in excess of 40,000 would be about two fish in the adult return for every redd lost. So long as escapements exceed 40,000, the issue of redd loss at Vernita Bar is simply a question of losing a few dozen or hundred adult fish in the next brood and is not an issue of stock conservation. 12 refs., 6 figs., 12 tabs.
Inclusive fitness maximization: An axiomatic approach.
Okasha, Samir; Weymark, John A; Bossert, Walter
2014-06-07
Kin selection theorists argue that evolution in social contexts will lead organisms to behave as if maximizing their inclusive, as opposed to personal, fitness. The inclusive fitness concept allows biologists to treat organisms as akin to rational agents seeking to maximize a utility function. Here we develop this idea and place it on a firm footing by employing a standard decision-theoretic methodology. We show how the principle of inclusive fitness maximization and a related principle of quasi-inclusive fitness maximization can be derived from axioms on an individual׳s 'as if preferences' (binary choices) for the case in which phenotypic effects are additive. Our results help integrate evolutionary theory and rational choice theory, help draw out the behavioural implications of inclusive fitness maximization, and point to a possible way in which evolution could lead organisms to implement it. Copyright © 2014 Elsevier Ltd. All rights reserved.
Stream Habitat Reach Summary - NCWAP [ds158
California Department of Resources — The Stream Habitat - NCWAP - Reach Summary [ds158] shapefile contains in-stream habitat survey data summarized to the stream reach level. It is a derivative of the...
A valid and reproducible protocol for testing maximal oxygen uptake in rabbits.
Gaustad, Svein Erik; Rolim, Natale; Wisløff, Ulrik
2010-02-01
Physiological studies of long-term cardiovascular adaptation to exercise require adequate testing procedures to quantify the outcome. Such test procedures are well established in rats and mice. However, the use of these species may have limitations, and to study several physiological parameters mimicking 'the human adaptation' larger animal models may be preferable. Here, we established a valid and reproducible exercise test protocol for measuring maximal oxygen uptake (VO2max) in rabbits. The VO2max protocol was studied in six adult female New Zealand White rabbits running on a treadmill at inclinations ranging from 0 to 20 degrees. VO2max was reached at all inclinations indicating that the rabbits reach exhaustion independent of inclination. Average VO2max for test and retest were 35.1+/-4.2 and 35.8+/-4.0 ml/kg per min, respectively. Oxygen uptake and heart rate increased linearly with increased running speed. Average running speed at VO2max was 0.51+/-0.09 m/s, and there was an increase oxygen pulse up to the intensity corresponding to VO2max, where it leveled off and declined. This study shows that rabbit is a suitable species for studying responses to training and could be of great importance for showing novel cellular cardiac adaptations to training.
Is there a maximal anabolic response to protein intake with a meal?
Deutz, Nicolaas EP; Wolfe, Robert R.
2012-01-01
Several recent publications indicate that the maximum stimulation of muscle protein fractional synthetic rate occurs with intake of 20 to 30 gms protein. This finding has led to the concept that there is a maximal anabolic response to protein intake with a meal, and that the normal amount of protein eaten with dinner will generally exceed the maximally-effective intake of protein.
An ethical justification of profit maximization
Koch, Carsten Allan
2010-01-01
In much of the literature on business ethics and corporate social responsibility, it is more or less taken for granted that attempts to maximize profits are inherently unethical. The purpose of this paper is to investigate whether an ethical argument can be given in support of profit maximizing...... behaviour. It is argued that some form of consequential ethics must be applied, and that both profit seeking and profit maximization can be defended from a rule-consequential point of view. It is noted, however, that the result does not apply unconditionally, but requires that certain form of profit (and...
Robust utility maximization in a discontinuous filtration
Jeanblanc, Monique; Ngoupeyou, Armand
2012-01-01
We study a problem of utility maximization under model uncertainty with information including jumps. We prove first that the value process of the robust stochastic control problem is described by the solution of a quadratic-exponential backward stochastic differential equation with jumps. Then, we establish a dynamic maximum principle for the optimal control of the maximization problem. The characterization of the optimal model and the optimal control (consumption-investment) is given via a forward-backward system which generalizes the result of Duffie and Skiadas (1994) and El Karoui, Peng and Quenez (2001) in the case of maximization of recursive utilities including model with jumps.
HEALTH INSURANCE: CONTRIBUTIONS AND REIMBURSEMENT MAXIMAL
HR Division
2000-01-01
Affected by both the salary adjustment index on 1.1.2000 and the evolution of the staff members and fellows population, the average reference salary, which is used as an index for fixed contributions and reimbursement maximal, has changed significantly. An adjustment of the amounts of the reimbursement maximal and the fixed contributions is therefore necessary, as from 1 January 2000.Reimbursement maximalThe revised reimbursement maximal will appear on the leaflet summarising the benefits for the year 2000, which will soon be available from the divisional secretariats and from the AUSTRIA office at CERN.Fixed contributionsThe fixed contributions, applicable to some categories of voluntarily insured persons, are set as follows (amounts in CHF for monthly contributions):voluntarily insured member of the personnel, with complete coverage:815,- (was 803,- in 1999)voluntarily insured member of the personnel, with reduced coverage:407,- (was 402,- in 1999)voluntarily insured no longer dependent child:326,- (was 321...
Maximizing throughput by evaluating critical utilization paths
Weeda, P.J.
1991-01-01
Recently the relationship between batch structure, bottleneck machine and maximum throughput has been explored for serial, convergent and divergent process configurations consisting of two machines and three processes. In three of the seven possible configurations a multiple batch structure maximize
Relationship between maximal exercise parameters and individual ...
Relationship between maximal exercise parameters and individual time trial ... It is widely accepted that the ventilatory threshold (VT) is an important ... This study investigated whether the physiological responses during a 20km time trial (TT) ...
Simple technique for maximal thoracic muscle harvest.
Marshall, M Blair; Kaiser, Larry R; Kucharczuk, John C
2004-04-01
We present a modification of technique for standard muscle flap harvest, the placement of cutaneous traction sutures. This technique allows for maximal dissection of the thoracic muscles even through minimal incisions. Through improved exposure and traction, complete dissection of the muscle bed can be performed and the tissue obtained maximized. Because more muscle bulk is obtained with this technique, the need for a second muscle may be prevented.
MAXIMAL POINTS OF A REGULAR TRUTH FUNCTION
Every canonical linearly separable truth function is a regular function, but not every regular truth function is linearly separable. The most...promising method of determining which of the regular truth functions are linearly separable r quires finding their maximal and minimal points. In this...report is developed a quick, systematic method of finding the maximal points of any regular truth function in terms of its arithmetic invariants. (Author)
Maximal Subgroups of Skew Linear Groups
M. Mahdavi-Hezavehi
2002-01-01
Let D be an infinite division algebra of finite dimension over its centre Z(D) = F, and n a positive integer. The structure of maximal subgroups of skew linear groups are investigated. In particular, assume N is a normal subgroup of GLn(D) and M is a maximal subgroup of N containing Z(N). It is shown that if M/Z(N) is finite, then N is central.
Additive Approximation Algorithms for Modularity Maximization
Kawase, Yasushi; Matsui, Tomomi; Miyauchi, Atsushi
2016-01-01
The modularity is a quality function in community detection, which was introduced by Newman and Girvan (2004). Community detection in graphs is now often conducted through modularity maximization: given an undirected graph $G=(V,E)$, we are asked to find a partition $\\mathcal{C}$ of $V$ that maximizes the modularity. Although numerous algorithms have been developed to date, most of them have no theoretical approximation guarantee. Recently, to overcome this issue, the design of modularity max...
Maximal Frequent Itemset Generation Using Segmentation Apporach
M.Rajalakshmi
2011-09-01
Full Text Available Finding frequent itemsets in a data source is a fundamental operation behind Association Rule Mining.Generally, many algorithms use either the bottom-up or top-down approaches for finding these frequentitemsets. When the length of frequent itemsets to be found is large, the traditional algorithms find all thefrequent itemsets from 1-length to n-length, which is a difficult process. This problem can be solved bymining only the Maximal Frequent Itemsets (MFS. Maximal Frequent Itemsets are frequent itemsets whichhave no proper frequent superset. Thus, the generation of only maximal frequent itemsets reduces thenumber of itemsets and also time needed for the generation of all frequent itemsets as each maximal itemsetof length m implies the presence of 2m-2 frequent itemsets. Furthermore, mining only maximal frequentitemset is sufficient in many data mining applications like minimal key discovery and theory extraction. Inthis paper, we suggest a novel method for finding the maximal frequent itemset from huge data sourcesusing the concept of segmentation of data source and prioritization of segments. Empirical evaluationshows that this method outperforms various other known methods.
Natural selection and the maximization of fitness.
Birch, Jonathan
2016-08-01
The notion that natural selection is a process of fitness maximization gets a bad press in population genetics, yet in other areas of biology the view that organisms behave as if attempting to maximize their fitness remains widespread. Here I critically appraise the prospects for reconciliation. I first distinguish four varieties of fitness maximization. I then examine two recent developments that may appear to vindicate at least one of these varieties. The first is the 'new' interpretation of Fisher's fundamental theorem of natural selection, on which the theorem is exactly true for any evolving population that satisfies some minimal assumptions. The second is the Formal Darwinism project, which forges links between gene frequency change and optimal strategy choice. In both cases, I argue that the results fail to establish a biologically significant maximization principle. I conclude that it may be a mistake to look for universal maximization principles justified by theory alone. A more promising approach may be to find maximization principles that apply conditionally and to show that the conditions were satisfied in the evolution of particular traits.
Maurice Schiff; Arvind Panagariya
1995-01-01
The traditional literature derives optimum and revenue-maximizing export taxes within two-country models. with one exporter and one importer (Johnson 1950-51, Tower 1977). In reality, most products, including primary products. are exported by several countries. In this paper, we present a theory of trade taxes in a three-country framework. This enables us to deal with strategic interactions among exporting countries. We show that (i) if one of the countries is a Stackelberg leader, both count...
Prange, Grada Berendina; Stienen, Arno; Jannink, M.J.A.; van der Kooij, Herman; IJzerman, Maarten Joost; Hermens, Hermanus J.; G.J. Gelderblom Bart Driessen, Just L. Herder
2007-01-01
To stimulate restoration of arm function after stroke, active movement is important, which can be facilitated by supporting the weight of the hemiparetic arm, either in conventional treatment or in other approaches such as robot-aided therapy. During arm support, the active range of motion during
Delagran, Louise; Vihstadt, Corrie; Evans, Roni
2015-09-01
Online educational interventions to teach evidence-based practice (EBP) are a promising mechanism for overcoming some of the barriers to incorporating research into practice. However, attention must be paid to aligning strategies with adult learning theories to achieve optimal outcomes. We describe the development of a series of short self-study modules, each covering a small set of learning objectives. Our approach, informed by design-based research (DBR), involved 6 phases: analysis, design, design evaluation, redesign, development/implementation, and evaluation. Participants were faculty and students in 3 health programs at a complementary and integrative educational institution. We chose a reusable learning object approach that allowed us to apply 4 main learning theories: events of instruction, cognitive load, dual processing, and ARCS (attention, relevance, confidence, satisfaction). A formative design evaluation suggested that the identified theories and instructional approaches were likely to facilitate learning and motivation. Summative evaluation was based on a student survey (N=116) that addressed how these theories supported learning. Results suggest that, overall, the selected theories helped students learn. The DBR approach allowed us to evaluate the specific intervention and theories for general applicability. This process also helped us define and document the intervention at a level of detail that covers almost all the proposed Guideline for Reporting Evidence-based practice Educational intervention and Teaching (GREET) items. This thorough description will facilitate the interpretation of future research and implementation of the intervention. Our approach can also serve as a model for others considering online EBP intervention development.
New symmetry of intended curved reaches
Torres Elizabeth B
2010-04-01
Full Text Available Abstract Background Movement regularities are inherently present in automated goal-directed motions of the primate's arm system. They can provide important signatures of intentional behaviours driven by sensory-motor strategies, but it remains unknown if during motor learning new regularities can be uncovered despite high variability in the temporal dynamics of the hand motions. Methods We investigated the conservation and violation of new movement regularity obtained from the hand motions traced by two untrained monkeys as they learned to reach outwardly towards spatial targets while avoiding obstacles in the dark. The regularity pertains to the transformation from postural to hand paths that aim at visual goals. Results In length-minimizing curves the area enclosed between the Euclidean straight line and the curve up to its point of maximum curvature is 1/2 of the total area. Similar trend is found if one examines the perimeter. This new movement regularity remained robust to striking changes in arm dynamics that gave rise to changes in the speed of the reach, to changes in the hand path curvature, and to changes in the arm's postural paths. The area and perimeter ratios characterizing the regularity co-varied across repeats of randomly presented targets whenever the transformation from posture to hand paths was compliant with the intended goals. To interpret this conservation and the cases in which the regularity was violated and recovered, we provide a geometric model that characterizes arm-to-hand and hand-to-arm motion paths as length minimizing curves (geodesics in a non-Euclidean space. Whenever the transformation from one space to the other is distance-metric preserving (isometric the two symmetric ratios co-vary. Otherwise, the symmetric ratios and their co-variation are violated. As predicted by the model we found empirical evidence for the violation of this movement regularity whenever the intended goals mismatched the actions. This
Welfare-maximizing and revenue-maximizing tariffs with a few domestic firms
Bruno Larue; Jean-Philippe Gervais
2002-01-01
In this paper we compare the orthodox optimal tariff formula with the appropriate welfare-maximizing tariff when there are a few producing or importing firms. The welfare-maximizing tariff can be very low, voire negative in some cases, while in others it can even exceed the maximum-revenue tariff. The relationship between the welfare-maximizing tariff and the number of firms need not be monotonically increasing, because the tariff is not strictly used to internalize terms of trade externality...
Reach preparation enhances visual performance and appearance.
Rolfs, Martin; Lawrence, Bonnie M; Carrasco, Marisa
2013-10-19
We investigated the impact of the preparation of reach movements on visual perception by simultaneously quantifying both an objective measure of visual sensitivity and the subjective experience of apparent contrast. Using a two-by-two alternative forced choice task, observers compared the orientation (clockwise or counterclockwise) and the contrast (higher or lower) of a Standard Gabor and a Test Gabor, the latter of which was presented during reach preparation, at the reach target location or the opposite location. Discrimination performance was better overall at the reach target than at the opposite location. Perceived contrast increased continuously at the target relative to the opposite location during reach preparation, that is, after the onset of the cue indicating the reach target. The finding that performance and appearance do not evolve in parallel during reach preparation points to a distinction with saccade preparation, for which we have shown previously there is a parallel temporal evolution of performance and appearance. Yet akin to saccade preparation, this study reveals that overall reach preparation enhances both visual performance and appearance.
Maximizing Complementary Quantities by Projective Measurements
M. Souza, Leonardo A.; Bernardes, Nadja K.; Rossi, Romeu
2017-04-01
In this work, we study the so-called quantitative complementarity quantities. We focus in the following physical situation: two qubits ( q A and q B ) are initially in a maximally entangled state. One of them ( q B ) interacts with a N-qubit system ( R). After the interaction, projective measurements are performed on each of the qubits of R, in a basis that is chosen after independent optimization procedures: maximization of the visibility, the concurrence, and the predictability. For a specific maximization procedure, we study in detail how each of the complementary quantities behave, conditioned on the intensity of the coupling between q B and the N qubits. We show that, if the coupling is sufficiently "strong," independent of the maximization procedure, the concurrence tends to decay quickly. Interestingly enough, the behavior of the concurrence in this model is similar to the entanglement dynamics of a two qubit system subjected to a thermal reservoir, despite that we consider finite N. However, the visibility shows a different behavior: its maximization is more efficient for stronger coupling constants. Moreover, we investigate how the distinguishability, or the information stored in different parts of the system, is distributed for different couplings.
Polyploidy Induction of Pteroceltis tatarinowii Maxim
Lin ZHANG; Feng WANG; Zhongkui SUN; Cuicui ZHU; Rongwei CHEN
2015-01-01
3%Objective] This study was conducted to obtain tetraploid Pteroceltis tatari-nowi Maxim. with excel ent ornamental traits. [Method] The stem apex growing points of Pteroceltis tatarinowi Maxim. were treated with different concentrations of colchicine solution for different hours to figure out a proper method and obtain poly-ploids. [Result] The most effective induction was obtained by treatment with 0.6%-0.8% colchicine for 72 h with 34.2% mutation rate. Flow cytometry and chromosome observation of the stem apex growing point of P. tatarinowi Maxim. proved that the tetraploid plants were successful y obtained with chromosome number 2n=4x=36. [Conclusion] The result not only fil s the blank of polyploid breeding of P. tatarinowi , but also provides an effective way to broaden the methods of cultivation of fast-growing, high-quality, disease-resilience, new varieties of Pteroceltis.
Quantum theory allows for absolute maximal contextuality
Amaral, Barbara; Cunha, Marcelo Terra; Cabello, Adán
2015-12-01
Contextuality is a fundamental feature of quantum theory and a necessary resource for quantum computation and communication. It is therefore important to investigate how large contextuality can be in quantum theory. Linear contextuality witnesses can be expressed as a sum S of n probabilities, and the independence number α and the Tsirelson-like number ϑ of the corresponding exclusivity graph are, respectively, the maximum of S for noncontextual theories and for the theory under consideration. A theory allows for absolute maximal contextuality if it has scenarios in which ϑ /α approaches n . Here we show that quantum theory allows for absolute maximal contextuality despite what is suggested by the examination of the quantum violations of Bell and noncontextuality inequalities considered in the past. Our proof is not constructive and does not single out explicit scenarios. Nevertheless, we identify scenarios in which quantum theory allows for almost-absolute-maximal contextuality.
The maximal process of nonlinear shot noise
Eliazar, Iddo; Klafter, Joseph
2009-05-01
In the nonlinear shot noise system-model shots’ statistics are governed by general Poisson processes, and shots’ decay-dynamics are governed by general nonlinear differential equations. In this research we consider a nonlinear shot noise system and explore the process tracking, along time, the system’s maximal shot magnitude. This ‘maximal process’ is a stationary Markov process following a decay-surge evolution; it is highly robust, and it is capable of displaying both a wide spectrum of statistical behaviors and a rich variety of random decay-surge sample-path trajectories. A comprehensive analysis of the maximal process is conducted, including its Markovian structure, its decay-surge structure, and its correlation structure. All results are obtained analytically and in closed-form.
Energy Band Calculations for Maximally Even Superlattices
Krantz, Richard; Byrd, Jason
2007-03-01
Superlattices are multiple-well, semiconductor heterostructures that can be described by one-dimensional potential wells separated by potential barriers. We refer to a distribution of wells and barriers based on the theory of maximally even sets as a maximally even superlattice. The prototypical example of a maximally even set is the distribution of white and black keys on a piano keyboard. Black keys may represent wells and the white keys represent barriers. As the number of wells and barriers increase, efficient and stable methods of calculation are necessary to study these structures. We have implemented a finite-element method using the discrete variable representation (FE-DVR) to calculate E versus k for these superlattices. Use of the FE-DVR method greatly reduces the amount of calculation necessary for the eigenvalue problem.
Absence of parasympathetic reactivation after maximal exercise.
de Oliveira, Tiago Peçanha; de Alvarenga Mattos, Raphael; da Silva, Rhenan Bartels Ferreira; Rezende, Rafael Andrade; de Lima, Jorge Roberto Perrout
2013-03-01
The ability of the human organism to recover its autonomic balance soon after physical exercise cessation has an important impact on the individual's health status. Although the dynamics of heart rate recovery after maximal exercise has been studied, little is known about heart rate variability after this type of exercise. The aim of this study is to analyse the dynamics of heart rate and heart rate variability recovery after maximal exercise in healthy young men. Fifteen healthy male subjects (21·7 ± 3·4 years; 24·0 ± 2·1 kg m(-2) ) participated in the study. The experimental protocol consisted of an incremental maximal exercise test on a cycle ergometer, until maximal voluntary exhaustion. After the test, recovery R-R intervals were recorded for 5 min. From the absolute differences between peak heart rate values and the heart rate values at 1 and 5 min of the recovery, the heart rate recovery was calculated. Postexercise heart rate variability was analysed from calculations of the SDNN and RMSSD indexes, in 30-s windows (SDNN(30s) and RMSSD(30s) ) throughout recovery. One and 5 min after maximal exercise cessation, the heart rate recovered 34·7 (±6·6) and 75·5 (±6·1) bpm, respectively. With regard to HRV recovery, while the SDNN(30s) index had a slight increase, RMSSD(30s) index remained totally suppressed throughout the recovery, suggesting an absence of vagal modulation reactivation and, possibly, a discrete sympathetic withdrawal. Therefore, it is possible that the main mechanism associated with the fall of HR after maximal exercise is sympathetic withdrawal or a vagal tone restoration without vagal modulation recovery. © 2012 The Authors Clinical Physiology and Functional Imaging © 2012 Scandinavian Society of Clinical Physiology and Nuclear Medicine.
Maximizing band gaps in plate structures
Halkjær, Søren; Sigmund, Ole; Jensen, Jakob Søndergaard
2006-01-01
Band gaps, i.e., frequency ranges in which waves cannot propagate, can be found in elastic structures for which there is a certain periodic modulation of the material properties or structure. In this paper, we maximize the band gap size for bending waves in a Mindlin plate. We analyze an infinite...... periodic plate using Bloch theory, which conveniently reduces the maximization problem to that of a single base cell. Secondly, we construct a finite periodic plate using a number of the optimized base cells in a postprocessed version. The dynamic properties of the finite plate are investigated...
Maximal and Minimal Congruences on Some Semigroups
Jintana SANWONG; Boorapa SINGHA; R.P.SULLIVAN
2009-01-01
In 2006,Sanwong and Sullivan described the maximal congruences on the semigroup N consisting of all non-negative integers under standard multiplication,and on the semigroup T(X) consisting of all total transformations of an infinite set X under composition. Here,we determine all maximal congruences on the semigroup Zn under multiplication modulo n. And,when Y X,we do the same for the semigroup T(X,Y) consisting of all elements of T(X) whose range is contained in Y. We also characterise the minimal congruences on T(X,Y).
Maximizing oil yields may not optimize economics
1987-03-01
The Los Alamos National Laboratory has used the ASPEN computer code to calculate the economics of different hydroretorting conditions. When the oil yield was maximized and a oil shale plant designed around this process, the costs turned out much higher than expected. However, calculations based on runs of less than maximum yields showed lower cost estimates. It is recommended that future efforts should be concentrated on minimizing production costs rather than maximizing yields. An oil shale plant has been designed around minimum production cost, but has not been able to be tested experimentally.
Maximal Inequalities for Dependent Random Variables
Hoffmann-Jorgensen, Jorgen
2016-01-01
Maximal inequalities play a crucial role in many probabilistic limit theorem; for instance, the law of large numbers, the law of the iterated logarithm, the martingale limit theorem and the central limit theorem. Let X-1, X-2,... be random variables with partial sums S-k = X-1 + ... + X-k. Then a......Maximal inequalities play a crucial role in many probabilistic limit theorem; for instance, the law of large numbers, the law of the iterated logarithm, the martingale limit theorem and the central limit theorem. Let X-1, X-2,... be random variables with partial sums S-k = X-1 + ... + X...
Singularity Structure of Maximally Supersymmetric Scattering Amplitudes
Arkani-Hamed, Nima; Bourjaily, Jacob L.; Cachazo, Freddy
2014-01-01
We present evidence that loop amplitudes in maximally supersymmetric (N=4) Yang-Mills theory (SYM) beyond the planar limit share some of the remarkable structures of the planar theory. In particular, we show that through two loops, the four-particle amplitude in full N=4 SYM has only logarithmic ...... singularities and is free of any poles at infinity—properties closely related to uniform transcendentality and the UV finiteness of the theory. We also briefly comment on implications for maximal (N=8) supergravity theory (SUGRA)....
Improving exposure scenario definitions within REACH
Lee, Jihyun; Pizzol, Massimo; Thomsen, Marianne
instruments to support a precautionary chemicals management system and to protect receptor’s health have also been increasing. Since 2007, the European Union adopted REACH (the Regulation on Registration, Evaluation, Authorisation and Restriction of Chemicals): REACH makes industry responsible for assessing...... the different background exposure between two countries allows in fact the definition of a common framework for improving exposure scenarios within REACH system, for monitoring environmental health, and for increasing degree of circularity of resource and substance flows. References 1. European Commission...
Compact muon solenoid magnet reaches full field
2006-01-01
Scientist of the U.S. Department of Energy in Fermilab and collaborators of the US/CMS project announced that the world's largest superconducting solenoid magnet has reached full field in tests at CERN. (1 apge)
Hanford Reach - Ringold Russian Knapweed Treatment
US Fish and Wildlife Service, Department of the Interior — Increase the diversity of the seed mix on approximately 250 acres in the Ringold Unit of the Hanford Reach National Monument (Monument) treated with aminopyralid as...
RICHY
Expanded Program on Immunisation (EPI) training in. Zambia and critically analyses ... excellence in skills such as sport, music or dance, so it is ... only improve through reaching every child both physically and in .... Non-verbal communication.
Women Reaching Equality in Dubious Habit: Drinking
... page: https://medlineplus.gov/news/fullstory_161640.html Women Reaching Equality in Dubious Habit: Drinking Females also ... 25, 2016 MONDAY, Oct. 24, 2016 (HealthDay News) -- Women have made major strides towards equality with men, ...
Reaching the Overlooked Student in Physical Education
Esslinger, Keri; Esslinger, Travis; Bagshaw, Jarad
2015-01-01
This article describes the use of live action role-playing, or "LARPing," as a non-traditional activity that has the potential to reach students who are not interested in traditional physical education.
Entropic anomaly and maximal efficiency of microscopic heat engines.
Bo, Stefano; Celani, Antonio
2013-05-01
The efficiency of microscopic heat engines in a thermally heterogenous environment is considered. We show that-as a consequence of the recently discovered entropic anomaly-quasistatic engines, whose efficiency is maximal in a fluid at uniform temperature, have in fact vanishing efficiency in the presence of temperature gradients. For slow cycles the efficiency falls off as the inverse of the period. The maximum efficiency is reached at a finite value of the cycle period that is inversely proportional to the square root of the gradient intensity. The relative loss in maximal efficiency with respect to the thermally homogeneous case grows as the square root of the gradient. As an illustration of these general results, we construct an explicit, analytically solvable example of a Carnot stochastic engine. In this thought experiment, a Brownian particle is confined by a harmonic trap and immersed in a fluid with a linear temperature profile. This example may serve as a template for the design of real experiments in which the effect of the entropic anomaly can be measured.
A New Algorithm to Optimize Maximal Information Coefficient.
Yuan Chen
Full Text Available The maximal information coefficient (MIC captures dependences between paired variables, including both functional and non-functional relationships. In this paper, we develop a new method, ChiMIC, to calculate the MIC values. The ChiMIC algorithm uses the chi-square test to terminate grid optimization and then removes the restriction of maximal grid size limitation of original ApproxMaxMI algorithm. Computational experiments show that ChiMIC algorithm can maintain same MIC values for noiseless functional relationships, but gives much smaller MIC values for independent variables. For noise functional relationship, the ChiMIC algorithm can reach the optimal partition much faster. Furthermore, the MCN values based on MIC calculated by ChiMIC can capture the complexity of functional relationships in a better way, and the statistical powers of MIC calculated by ChiMIC are higher than those calculated by ApproxMaxMI. Moreover, the computational costs of ChiMIC are much less than those of ApproxMaxMI. We apply the MIC values tofeature selection and obtain better classification accuracy using features selected by the MIC values from ChiMIC.
Cycle-maximal triangle-free graphs
Durocher, Stephane; Gunderson, David S.; Li, Pak Ching;
2015-01-01
Abstract We conjecture that the balanced complete bipartite graph K ⌊ n / 2 ⌋ , ⌈ n / 2 ⌉ contains more cycles than any other n -vertex triangle-free graph, and we make some progress toward proving this. We give equivalent conditions for cycle-maximal triangle-free graphs; show bounds...
Robust Utility Maximization Under Convex Portfolio Constraints
Matoussi, Anis, E-mail: anis.matoussi@univ-lemans.fr [Université du Maine, Risk and Insurance institut of Le Mans Laboratoire Manceau de Mathématiques (France); Mezghani, Hanen, E-mail: hanen.mezghani@lamsin.rnu.tn; Mnif, Mohamed, E-mail: mohamed.mnif@enit.rnu.tn [University of Tunis El Manar, Laboratoire de Modélisation Mathématique et Numérique dans les Sciences de l’Ingénieur, ENIT (Tunisia)
2015-04-15
We study a robust maximization problem from terminal wealth and consumption under a convex constraints on the portfolio. We state the existence and the uniqueness of the consumption–investment strategy by studying the associated quadratic backward stochastic differential equation. We characterize the optimal control by using the duality method and deriving a dynamic maximum principle.
Maximizing the Motivated Mind for Emergent Giftedness.
Rea, Dan
2001-01-01
This article explains how the theory of the motivated mind conceptualizes the productive interaction of intelligence, creativity, and achievement motivation and how this theory can help educators to maximize students' emergent potential for giftedness. It discusses the integration of cold-order thinking and hot-chaotic thinking into fluid-adaptive…
The Winning Edge: Maximizing Success in College.
Schmitt, David E.
This book offers college students ideas on how to maximize their success in college by examining the personal management techniques a student needs to succeed. Chapters are as follows: "Getting and Staying Motivated"; "Setting Goals and Tapping Your Resources"; "Conquering Time"; "Think Yourself to College Success"; "Understanding and Remembering…
MAXIMAL ELEMENTS AND EQUILIBRIUM OF ABSTRACT ECONOMY
刘心歌; 蔡海涛
2001-01-01
An existence theorem of maximal elements for a new type of preference correspondences which are Qθ-majorized is given. Then some existence theorems of equilibrium for abstract economy and qualitative game in which the constraint or preference correspondences are Qθ-majorized are obtained in locally convex topological vector spaces.
DNA solution of the maximal clique problem.
Ouyang, Q; Kaplan, P D; Liu, S; Libchaber, A
1997-10-17
The maximal clique problem has been solved by means of molecular biology techniques. A pool of DNA molecules corresponding to the total ensemble of six-vertex cliques was built, followed by a series of selection processes. The algorithm is highly parallel and has satisfactory fidelity. This work represents further evidence for the ability of DNA computing to solve NP-complete search problems.
Maximal workload capacity on moving platforms
Heus, R.; Wertheim, A.H.
1996-01-01
Physical tasks on a moving platform required more energy than the same tasks on a non-moving platform. In this study the maximum aerobic performance (defined as V_O2max) of people working on a moving floor was established compared to the maximal aerobic performance on a non-moving floor. The main
Maximal workload capacity on moving platforms
Heus, R.; Wertheim, A.H.
1996-01-01
Physical tasks on a moving platform required more energy than the same tasks on a non-moving platform. In this study the maximum aerobic performance (defined as V_O2max) of people working on a moving floor was established compared to the maximal aerobic performance on a non-moving floor. The main qu
Maximizing Resource Utilization in Video Streaming Systems
Alsmirat, Mohammad Abdullah
2013-01-01
Video streaming has recently grown dramatically in popularity over the Internet, Cable TV, and wire-less networks. Because of the resource demanding nature of video streaming applications, maximizing resource utilization in any video streaming system is a key factor to increase the scalability and decrease the cost of the system. Resources to…
Maximizing throughput in an automated test system
朱君
2007-01-01
@@ Overview This guide is collection of whitepapers designed to help you develop test systems that lower your cost, increase your test throughput, and can scale with future requirements. This whitepaper provides strategies for maximizing system throughput. To download the complete developers guide (120 pages), visit ni. com/automatedtest.
The gaugings of maximal D=6 supergravity
Bergshoeff, E.; Samtleben, H.; Sezgin, E.
2008-01-01
We construct the most general gaugings of the maximal D = 6 supergravity. The theory is ( 2, 2) supersymmetric, and possesses an on-shell SO( 5, 5) duality symmetry which plays a key role in determining its couplings. The field content includes 16 vector fields that carry a chiral spinor representat
WEIGHTED BOUNDEDNESS OF A ROUGH MAXIMAL OPERATOR
无
2000-01-01
In this note the authors give the weighted Lp-boundedness fora class of maximal singular integral operators with rough kernel.The result in this note is an improvement and extension ofthe result obtained by Chen and Lin in 1990.
Maximizing the Range of a Projectile.
Brown, Ronald A.
1992-01-01
Discusses solutions to the problem of maximizing the range of a projectile. Presents three references that solve the problem with and without the use of calculus. Offers a fourth solution suitable for introductory physics courses that relies more on trigonometry and the geometry of the problem. (MDH)
Ehrenfest's Lottery--Time and Entropy Maximization
Ashbaugh, Henry S.
2010-01-01
Successful teaching of the Second Law of Thermodynamics suffers from limited simple examples linking equilibrium to entropy maximization. I describe a thought experiment connecting entropy to a lottery that mixes marbles amongst a collection of urns. This mixing obeys diffusion-like dynamics. Equilibrium is achieved when the marble distribution is…
Testing maximality in muon neutrino flavor mixing
Choubey, S; Choubey, Sandhya; Roy, Probir
2003-01-01
The small difference between the survival probabilities of muon neutrino and antineutrino beams, traveling through earth matter in a long baseline experiment such as MINOS, is shown to be an important measure of any possible deviation from maximality in the flavor mixing of those states.
Average utility maximization: A preference foundation
A.V. Kothiyal (Amit); V. Spinu (Vitalie); P.P. Wakker (Peter)
2014-01-01
textabstractThis paper provides necessary and sufficient preference conditions for average utility maximization over sequences of variable length. We obtain full generality by using a new algebraic technique that exploits the richness structure naturally provided by the variable length of the sequen
On the Hardy-Littlewood maximal theorem
Shinji Yamashita
1982-01-01
Full Text Available The Hardy-Littlewood maximal theorem is extended to functions of class PL in the sense of E. F. Beckenbach and T. Radó, with a more precise expression of the absolute constant in the inequality. As applications we deduce some results on hyperbolic Hardy classes in terms of the non-Euclidean hyperbolic distance in the unit disk.
Maximal Cartel Pricing and Leniency Programs
Houba, H.E.D.; Motchenkova, E.; Wen, Q.
2008-01-01
For a general class of oligopoly models with price competition, we analyze the impact of ex-ante leniency programs in antitrust regulation on the endogenous maximal-sustainable cartel price. This impact depends upon industry characteristics including its cartel culture. Our analysis disentangles the
How to Generate Good Profit Maximization Problems
Davis, Lewis
2014-01-01
In this article, the author considers the merits of two classes of profit maximization problems: those involving perfectly competitive firms with quadratic and cubic cost functions. While relatively easy to develop and solve, problems based on quadratic cost functions are too simple to address a number of important issues, such as the use of…
Ehrenfest's Lottery--Time and Entropy Maximization
Ashbaugh, Henry S.
2010-01-01
Successful teaching of the Second Law of Thermodynamics suffers from limited simple examples linking equilibrium to entropy maximization. I describe a thought experiment connecting entropy to a lottery that mixes marbles amongst a collection of urns. This mixing obeys diffusion-like dynamics. Equilibrium is achieved when the marble distribution is…
Maximally entangled mixed states made easy
Aiello, A; Voigt, D; Woerdman, J P
2006-01-01
We show that, contrarily to a recent claim [M. Ziman and V. Bu\\v{z}ek, Phys. Rev. A. \\textbf{72}, 052325 (2005)], it is possible to achieve maximally entangled mixed states of two qubits from the singlet state via the action of local nonunital quantum channels. Moreover, we present a simple, feasible linear optical implementation of one of such channels.
Maximizing Resource Utilization in Video Streaming Systems
Alsmirat, Mohammad Abdullah
2013-01-01
Video streaming has recently grown dramatically in popularity over the Internet, Cable TV, and wire-less networks. Because of the resource demanding nature of video streaming applications, maximizing resource utilization in any video streaming system is a key factor to increase the scalability and decrease the cost of the system. Resources to…
Maximizing scientific knowledge from randomized clinical trials
Gustafsson, Finn; Atar, Dan; Pitt, Bertram
2010-01-01
Trialists have an ethical and financial responsibility to plan and conduct clinical trials in a manner that will maximize the scientific knowledge gained from the trial. However, the amount of scientific information generated by randomized clinical trials in cardiovascular medicine is highly...
Maximal Heat Generation in Nanoscale Systems
ZHOU Li-Ling; LI Shu-Shen; ZENG Zhao-Yang
2009-01-01
We investigate the heat generation in a nanoscale system coupled to normal leads and find that it is maximal when the average occupation of the electrons in the nanoscale system is 0.5,no matter what mechanism induces the heat generation.
Understanding violations of Gricean maxims in preschoolers and adults.
Okanda, Mako; Asada, Kosuke; Moriguchi, Yusuke; Itakura, Shoji
2015-01-01
This study used a revised Conversational Violations Test to examine Gricean maxim violations in 4- to 6-year-old Japanese children and adults. Participants' understanding of the following maxims was assessed: be informative (first maxim of quantity), avoid redundancy (second maxim of quantity), be truthful (maxim of quality), be relevant (maxim of relation), avoid ambiguity (second maxim of manner), and be polite (maxim of politeness). Sensitivity to violations of Gricean maxims increased with age: 4-year-olds' understanding of maxims was near chance, 5-year-olds understood some maxims (first maxim of quantity and maxims of quality, relation, and manner), and 6-year-olds and adults understood all maxims. Preschoolers acquired the maxim of relation first and had the greatest difficulty understanding the second maxim of quantity. Children and adults differed in their comprehension of the maxim of politeness. The development of the pragmatic understanding of Gricean maxims and implications for the construction of developmental tasks from early childhood to adulthood are discussed.
Understanding Violations of Gricean Maxims in Preschoolers and Adults
Mako eOkanda
2015-07-01
Full Text Available This study used a revised Conversational Violations Test to examine Gricean maxim violations in 4- to 6-year-old Japanese children and adults. Participants’ understanding of the following maxims was assessed: be informative (first maxim of quantity, avoid redundancy (second maxim of quantity, be truthful (maxim of quality, be relevant (maxim of relation, avoid ambiguity (second maxim of manner, and be polite (maxim of politeness. Sensitivity to violations of Gricean maxims increased with age: 4-year-olds’ understanding of maxims was near chance, 5-year-olds understood some maxims (first maxim of quantity and maxims of quality, relation, and manner, and 6-year-olds and adults understood all maxims. Preschoolers acquired the maxim of relation first and had the greatest difficulty understanding the second maxim of quantity. Children and adults differed in their comprehension of the maxim of politeness. The development of the pragmatic understanding of Gricean maxims and implications for the construction of developmental tasks from early childhood to adulthood are discussed.
Impact of the REACH II and REACH VA Dementia Caregiver Interventions on Healthcare Costs.
Nichols, Linda O; Martindale-Adams, Jennifer; Zhu, Carolyn W; Kaplan, Erin K; Zuber, Jeffrey K; Waters, Teresa M
2017-05-01
Examine caregiver and care recipient healthcare costs associated with caregivers' participation in Resources for Enhancing Alzheimer's Caregivers Health (REACH II or REACH VA) behavioral interventions to improve coping skills and care recipient management. RCT (REACH II); propensity-score matched, retrospective cohort study (REACH VA). Five community sites (REACH II); 24 VA facilities (REACH VA). Care recipients with Alzheimer's disease and related dementias (ADRD) and their caregivers who participated in REACH II study (analysis sample of 110 caregivers and 197 care recipients); care recipients whose caregivers participated in REACH VA and a propensity matched control group (analysis sample of 491). Previously collected data plus Medicare expenditures (REACH II) and VA costs plus Medicare expenditures (REACH VA). There was no increase in VA or Medicare expenditures for care recipients or their caregivers who participated in either REACH intervention. For VA care recipients, REACH was associated with significantly lower total VA costs of care (33.6%). VA caregiver cost data was not available. In previous research, both REACH II and REACH VA have been shown to provide benefit for dementia caregivers at a cost of less than $5/day; however, concerns about additional healthcare costs may have hindered REACH's widespread adoption. Neither REACH intervention was associated with additional healthcare costs for caregivers or patients; in fact, for VA patients, there were significantly lower healthcare costs. The VA costs savings may be related to the addition of a structured format for addressing the caregiver's role in managing complex ADRD care to an existing, integrated care system. These findings suggest that behavioral interventions are a viable mechanism to support burdened dementia caregivers without additional healthcare costs. © 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics Society.
Reference values of maximal oxygen uptake for polish rowers.
Klusiewicz, Andrzej; Starczewski, Michał; Ładyga, Maria; Długołęcka, Barbara; Braksator, Wojciech; Mamcarz, Artur; Sitkowski, Dariusz
2014-12-09
The aim of this study was to characterize changes in maximal oxygen uptake over several years and to elaborate current reference values of this index based on determinations carried out in large and representative groups of top Polish rowers. For this study 81 female and 159 male rowers from the sub-junior to senior categories were recruited from the Polish National Team and its direct backup. All the subjects performed an incremental exercise test on a rowing ergometer. During the test maximal oxygen uptake was measured with the BxB method. The calculated reference values for elite Polish junior and U23 rowers allowed to evaluate the athletes' fitness level against the respective reference group and may aid the coach in controlling the training process. Mean values of VO2max achieved by members of the top Polish rowing crews who over the last five years competed in the Olympic Games or World Championships were also presented. The results of the research on the "trainability" of the maximal oxygen uptake may lead to a conclusion that the growth rate of the index is larger in case of high-level athletes and that the index (in absolute values) increases significantly between the age of 19-22 years (U23 category).
Memory-guided reaching in a patient with visual hemiagnosia.
Cornelsen, Sonja; Rennig, Johannes; Himmelbach, Marc
2016-06-01
The two-visual-systems hypothesis (TVSH) postulates that memory-guided movements rely on intact functions of the ventral stream. Its particular importance for memory-guided actions was initially inferred from behavioral dissociations in the well-known patient DF. Despite of rather accurate reaching and grasping movements to visible targets, she demonstrated grossly impaired memory-guided grasping as much as impaired memory-guided reaching. These dissociations were later complemented by apparently reversed dissociations in patients with dorsal damage and optic ataxia. However, grasping studies in DF and optic ataxia patients differed with respect to the retinotopic position of target objects, questioning the interpretation of the respective findings as a double dissociation. In contrast, the findings for reaching errors in both types of patients came from similar peripheral target presentations. However, new data on brain structural changes and visuomotor deficits in DF also questioned the validity of a double dissociation in reaching. A severe visuospatial short-term memory deficit in DF further questioned the specificity of her memory-guided reaching deficit. Therefore, we compared movement accuracy in visually-guided and memory-guided reaching in a new patient who suffered a confined unilateral damage to the ventral visual system due to stroke. Our results indeed support previous descriptions of memory-guided movements' inaccuracies in DF. Furthermore, our data suggest that recently discovered optic-ataxia like misreaching in DF is most likely caused by her parieto-occipital and not by her ventral stream damage. Finally, multiple visuospatial memory measurements in HWS suggest that inaccuracies in memory-guided reaching tasks in patients with ventral damage cannot be explained by visuospatial short-term memory or perceptual deficits, but by a specific deficit in visuomotor processing.
... take place on hard surfaces, such as track, basketball, soccer, and gymnastics. Sever's disease also can result ... diagnosing Sever's disease, some doctors order them to rule out other problems, such as fractures. Sever's disease ...
Maximal power output estimates the MLSS before and after aerobic training
Carolina Franco Wilke; Guilherme Passos Ramos; André Maia Lima; Christian Emmanuel Torres Cabido; Cristiano Lino Monteiro de Barros; Thiago Teixeira Mendes; Emerson Silami Garcia
2014-01-01
The purpose of this study is to present an equation to predict the maximal lactate steady state (MLSS) through a VO2peak incremental protocol. Twenty-six physically active men were divided in two groups (G1 and G2). They performed one maximal incremental test to determine their VO2peak and maximal power output (Wpeak), and also several constant intensity tests to determine MLSS intensity (MLSSw) on a cycle ergometer. Group G2 underwent six weeks of aerobic training at MLSSw. A regression equa...
Do working environment interventions reach shift workers?
Nabe-Nielsen, Kirsten; Jørgensen, Marie Birk; Garde, Anne Helene
2016-01-01
workers were less likely to be reached by workplace interventions. For example, night workers less frequently reported that they had got more flexibility (OR 0.5; 95 % CI 0.3-0.7) or that they had participated in improvements of the working procedures (OR 0.6; 95 % CI 0.5-0.8). Quality of leadership......PURPOSE: Shift workers are exposed to more physical and psychosocial stressors in the working environment as compared to day workers. Despite the need for targeted prevention, it is likely that workplace interventions less frequently reach shift workers. The aim was therefore to investigate whether...... the reach of workplace interventions varied between shift workers and day workers and whether such differences could be explained by the quality of leadership exhibited at different times of the day. METHODS: We used questionnaire data from 5361 female care workers in the Danish eldercare sector...
Measurable Maximal Energy and Minimal Time Interval
Dahab, Eiman Abou El
2014-01-01
The possibility of finding the measurable maximal energy and the minimal time interval is discussed in different quantum aspects. It is found that the linear generalized uncertainty principle (GUP) approach gives a non-physical result. Based on large scale Schwarzshild solution, the quadratic GUP approach is utilized. The calculations are performed at the shortest distance, at which the general relativity is assumed to be a good approximation for the quantum gravity and at larger distances, as well. It is found that both maximal energy and minimal time have the order of the Planck time. Then, the uncertainties in both quantities are accordingly bounded. Some physical insights are addressed. Also, the implications on the physics of early Universe and on quantized mass are outlined. The results are related to the existence of finite cosmological constant and minimum mass (mass quanta).
Hamiltonian formalism and path entropy maximization
Davis, Sergio; González, Diego
2015-10-01
Maximization of the path information entropy is a clear prescription for constructing models in non-equilibrium statistical mechanics. Here it is shown that, following this prescription under the assumption of arbitrary instantaneous constraints on position and velocity, a Lagrangian emerges which determines the most probable trajectory. Deviations from the probability maximum can be consistently described as slices in time by a Hamiltonian, according to a nonlinear Langevin equation and its associated Fokker-Planck equation. The connections unveiled between the maximization of path entropy and the Langevin/Fokker-Planck equations imply that missing information about the phase space coordinate never decreases in time, a purely information-theoretical version of the second law of thermodynamics. All of these results are independent of any physical assumptions, and thus valid for any generalized coordinate as a function of time, or any other parameter. This reinforces the view that the second law is a fundamental property of plausible inference.
Predicting Contextual Sequences via Submodular Function Maximization
Dey, Debadeepta; Hebert, Martial; Bagnell, J Andrew
2012-01-01
Sequence optimization, where the items in a list are ordered to maximize some reward has many applications such as web advertisement placement, search, and control libraries in robotics. Previous work in sequence optimization produces a static ordering that does not take any features of the item or context of the problem into account. In this work, we propose a general approach to order the items within the sequence based on the context (e.g., perceptual information, environment description, and goals). We take a simple, efficient, reduction-based approach where the choice and order of the items is established by repeatedly learning simple classifiers or regressors for each "slot" in the sequence. Our approach leverages recent work on submodular function maximization to provide a formal regret reduction from submodular sequence optimization to simple cost-sensitive prediction. We apply our contextual sequence prediction algorithm to optimize control libraries and demonstrate results on two robotics problems: ...
Nonlinear trading models through Sharpe Ratio maximization.
Choey, M; Weigend, A S
1997-08-01
While many trading strategies are based on price prediction, traders in financial markets are typically interested in optimizing risk-adjusted performance such as the Sharpe Ratio, rather than the price predictions themselves. This paper introduces an approach which generates a nonlinear strategy that explicitly maximizes the Sharpe Ratio. It is expressed as a neural network model whose output is the position size between a risky and a risk-free asset. The iterative parameter update rules are derived and compared to alternative approaches. The resulting trading strategy is evaluated and analyzed on both computer-generated data and real world data (DAX, the daily German equity index). Trading based on Sharpe Ratio maximization compares favorably to both profit optimization and probability matching (through cross-entropy optimization). The results show that the goal of optimizing out-of-sample risk-adjusted profit can indeed be achieved with this nonlinear approach.
Maximally Symmetric Spacetimes emerging from thermodynamic fluctuations
Bravetti, A; Quevedo, H
2015-01-01
In this work we prove that the maximally symmetric vacuum solutions of General Relativity emerge from the geometric structure of statistical mechanics and thermodynamic fluctuation theory. To present our argument, we begin by showing that the pseudo-Riemannian structure of the Thermodynamic Phase Space is a solution to the vacuum Einstein-Gauss-Bonnet theory of gravity with a cosmological constant. Then, we use the geometry of equilibrium thermodynamics to demonstrate that the maximally symmetric vacuum solutions of Einstein's Field Equations -- Minkowski, de-Sitter and Anti-de-Sitter spacetimes -- correspond to thermodynamic fluctuations. Moreover, we argue that these might be the only possible solutions that can be derived in this manner. Thus, the results presented here are the first concrete examples of spacetimes effectively emerging from the thermodynamic limit over an unspecified microscopic theory without any further assumptions.
Consistent 4-form fluxes for maximal supergravity
Godazgar, Hadi; Krueger, Olaf; Nicolai, Hermann
2015-01-01
We derive new ansaetze for the 4-form field strength of D=11 supergravity corresponding to uplifts of four-dimensional maximal gauged supergravity. In particular, the ansaetze directly yield the components of the 4-form field strength in terms of the scalars and vectors of the four-dimensional maximal gauged supergravity---in this way they provide an explicit uplift of all four-dimensional consistent truncations of D=11 supergravity. The new ansaetze provide a substantially simpler method for uplifting d=4 flows compared to the previously available method using the 3-form and 6-form potential ansaetze. The ansatz for the Freund-Rubin term allows us to conjecture a `master formula' for the latter in terms of the scalar potential of d=4 gauged supergravity and its first derivative. We also resolve a long-standing puzzle concerning the antisymmetry of the flux obtained from uplift ansaetze.
REACH. Analytical characterisation of petroleum UVCB substances
De Graaff, R.; Forbes, S.; Gennart, J.P.; Gimeno Cortes, M.J.; Hovius, H.; King, D.; Kleise, H.; Martinez Martin, C.; Montanari, L.; Pinzuti, M.; Pollack, H.; Ruggieri, P.; Thomas, M.; Walton, A.; Dmytrasz, B.
2012-10-15
The purpose of this report is to summarise the findings of the scientific and technical work undertaken by CONCAWE to assess the feasibility and potential benefit of characterising petroleum UVCB substances (Substances of Unknown or Variable Composition, Complex reaction products or Biological Materials) beyond the recommendations issued by CONCAWE for the substance identification of petroleum substances under REACH. REACH is the European Community Regulation on chemicals and their safe use (EC 1907/2006). It deals with the Registration, Evaluation, Authorisation and Restriction of Chemical substances. The report is based on Member Company experience of the chemical analysis of petroleum UVCB substances, including analysis in support of REACH registrations undertaken in 2010. This report is structured into four main sections, namely: Section 1 which provides an introduction to the subject of petroleum UVCB substance identification including the purpose of the report, regulatory requirements, the nature of petroleum UVCB substances, and CONCAWE's guidance to Member Companies and other potential registrants. Section 2 provides a description of the capabilities of each of the analytical techniques described in the REACH Regulation. This section also includes details on the type of analytical information obtained by each technique and an evaluation of what each technique can provide for the characterisation of petroleum UVCB substances. Section 3 provides a series of case studies for six petroleum substance categories (low boiling point naphthas, kerosene, heavy fuel oils, other lubricant base oils, residual aromatic extracts and bitumens) to illustrate the value of the information derived from each analytical procedure, and provide an explanation for why some techniques are not scientifically necessary. Section 4 provides a summary of the conclusions reached from the technical investigations undertaken by CONCAWE Member Companies, and summarising the
Utility maximization in incomplete markets with default
Lim, Thomas
2008-01-01
We adress the maximization problem of expected utility from terminal wealth. The special feature of this paper is that we consider a financial market where the price process of risky assets can have a default time. Using dynamic programming, we characterize the value function with a backward stochastic differential equation and the optimal portfolio policies. We separately treat the cases of exponential, power and logarithmic utility.
Operational Modal Analysis using Expectation Maximization Algorithm
Cara Cañas, Francisco Javier; Carpio Huertas, Jaime; Juan Ruiz, Jesús; Alarcón Álvarez, Enrique
2011-01-01
This paper presents a time-domain stochastic system identification method based on Maximum Likelihood Estimation and the Expectation Maximization algorithm. The effectiveness of this structural identification method is evaluated through numerical simulation in the context of the ASCE benchmark problem on structural health monitoring. Modal parameters (eigenfrequencies, damping ratios and mode shapes) of the benchmark structure have been estimated applying the proposed identification method...
Revenue Maximizing Head Starts in Contests
Franke, Jörg; Leininger, Wolfgang; Wasser, Cédric
2014-01-01
We characterize revenue maximizing head starts for all-pay auctions and lottery contests with many heterogeneous players. We show that under optimal head starts all-pay auctions revenue-dominate lottery contests for any degree of heterogeneity among players. Moreover, all-pay auctions with optimal head starts induce higher revenue than any multiplicatively biased all-pay auction or lottery contest. While head starts are more effective than multiplicative biases in all-pay auctions, they are l...
Approximate Revenue Maximization in Interdependent Value Settings
Chawla, Shuchi; Fu, Hu; Karlin, Anna
2014-01-01
We study revenue maximization in settings where agents' values are interdependent: each agent receives a signal drawn from a correlated distribution and agents' values are functions of all of the signals. We introduce a variant of the generalized VCG auction with reserve prices and random admission, and show that this auction gives a constant approximation to the optimal expected revenue in matroid environments. Our results do not require any assumptions on the signal distributions, however, ...
Maximal supersymmetry and B-mode targets
Kallosh, Renata; Linde, Andrei; Wrase, Timm; Yamada, Yusuke
2017-04-01
Extending the work of Ferrara and one of the authors [1], we present dynamical cosmological models of α-attractors with plateau potentials for 3 α = 1, 2, 3, 4, 5, 6, 7. These models are motivated by geometric properties of maximally supersymmetric theories: M-theory, superstring theory, and maximal N = 8 supergravity. After a consistent truncation of maximal to minimal supersymmetry in a seven-disk geometry, we perform a two-step procedure: 1) we introduce a superpotential, which stabilizes the moduli of the seven-disk geometry in a supersymmetric minimum, 2) we add a cosmological sector with a nilpotent stabilizer, which breaks supersymmetry spontaneously and leads to a desirable class of cosmological attractor models. These models with n s consistent with observational data, and with tensor-to-scalar ratio r ≈ 10-2 - 10-3, provide natural targets for future B-mode searches. We relate the issue of stability of inflationary trajectories in these models to tessellations of a hyperbolic geometry.
Can factitious disorder reach delusional level? A case study
Dubiel Rafał
2016-12-01
Full Text Available The paper describes a patient, who has been consulted and hospitalized multiple times, due to dermatological lesions on his face. We will present his medical history and describe circumstances leading to the final diagnosis of factitious disorder. In the theoretical part we will try to answer the question, whether the extreme severity of the factitious disorders can, at some point, reach the level of delusions.
In vivo maximal fascicle-shortening velocity during plantar flexion in humans.
Hauraix, Hugo; Nordez, Antoine; Guilhem, Gaël; Rabita, Giuseppe; Dorel, Sylvain
2015-12-01
Interindividual variability in performance of fast movements is commonly explained by a difference in maximal muscle-shortening velocity due to differences in the proportion of fast-twitch fibers. To provide a better understanding of the capacity to generate fast motion, this study aimed to 1) measure for the first time in vivo the maximal fascicle-shortening velocity of human muscle; 2) evaluate the relationship between angular velocity and fascicle-shortening velocity from low to maximal angular velocities; and 3) investigate the influence of musculo-articular features (moment arm, tendinous tissues stiffness, and muscle architecture) on maximal angular velocity. Ultrafast ultrasound images of the gastrocnemius medialis were obtained from 31 participants during maximal isokinetic and light-loaded plantar flexions. A strong linear relationship between fascicle-shortening velocity and angular velocity was reported for all subjects (mean R(2) = 0.97). The maximal shortening velocity (V(Fmax)) obtained during the no-load condition (NLc) ranged between 18.8 and 43.3 cm/s. V(Fmax) values were very close to those of the maximal shortening velocity (V(max)), which was extrapolated from the F-V curve (the Hill model). Angular velocity reached during the NLc was significantly correlated with this V(Fmax) (r = 0.57; P < 0.001). This finding was in agreement with assumptions about the role of muscle fiber type, whereas interindividual comparisons clearly support the fact that other parameters may also contribute to performance during fast movements. Nevertheless, none of the biomechanical features considered in the present study were found to be directly related to the highest angular velocity, highlighting the complexity of the upstream mechanics that lead to maximal-velocity muscle contraction.
Cardiorespiratory Coordination in Repeated Maximal Exercise
Sergi Garcia-Retortillo
2017-06-01
Full Text Available Increases in cardiorespiratory coordination (CRC after training with no differences in performance and physiological variables have recently been reported using a principal component analysis approach. However, no research has yet evaluated the short-term effects of exercise on CRC. The aim of this study was to delineate the behavior of CRC under different physiological initial conditions produced by repeated maximal exercises. Fifteen participants performed 2 consecutive graded and maximal cycling tests. Test 1 was performed without any previous exercise, and Test 2 6 min after Test 1. Both tests started at 0 W and the workload was increased by 25 W/min in males and 20 W/min in females, until they were not able to maintain the prescribed cycling frequency of 70 rpm for more than 5 consecutive seconds. A principal component (PC analysis of selected cardiovascular and cardiorespiratory variables (expired fraction of O2, expired fraction of CO2, ventilation, systolic blood pressure, diastolic blood pressure, and heart rate was performed to evaluate the CRC defined by the number of PCs in both tests. In order to quantify the degree of coordination, the information entropy was calculated and the eigenvalues of the first PC (PC1 were compared between tests. Although no significant differences were found between the tests with respect to the performed maximal workload (Wmax, maximal oxygen consumption (VO2 max, or ventilatory threshold (VT, an increase in the number of PCs and/or a decrease of eigenvalues of PC1 (t = 2.95; p = 0.01; d = 1.08 was found in Test 2 compared to Test 1. Moreover, entropy was significantly higher (Z = 2.33; p = 0.02; d = 1.43 in the last test. In conclusion, despite the fact that no significant differences were observed in the conventionally explored maximal performance and physiological variables (Wmax, VO2 max, and VT between tests, a reduction of CRC was observed in Test 2. These results emphasize the interest of CRC
Cardiorespiratory Coordination in Repeated Maximal Exercise.
Garcia-Retortillo, Sergi; Javierre, Casimiro; Hristovski, Robert; Ventura, Josep L; Balagué, Natàlia
2017-01-01
Increases in cardiorespiratory coordination (CRC) after training with no differences in performance and physiological variables have recently been reported using a principal component analysis approach. However, no research has yet evaluated the short-term effects of exercise on CRC. The aim of this study was to delineate the behavior of CRC under different physiological initial conditions produced by repeated maximal exercises. Fifteen participants performed 2 consecutive graded and maximal cycling tests. Test 1 was performed without any previous exercise, and Test 2 6 min after Test 1. Both tests started at 0 W and the workload was increased by 25 W/min in males and 20 W/min in females, until they were not able to maintain the prescribed cycling frequency of 70 rpm for more than 5 consecutive seconds. A principal component (PC) analysis of selected cardiovascular and cardiorespiratory variables (expired fraction of O2, expired fraction of CO2, ventilation, systolic blood pressure, diastolic blood pressure, and heart rate) was performed to evaluate the CRC defined by the number of PCs in both tests. In order to quantify the degree of coordination, the information entropy was calculated and the eigenvalues of the first PC (PC1) were compared between tests. Although no significant differences were found between the tests with respect to the performed maximal workload (Wmax), maximal oxygen consumption (VO2 max), or ventilatory threshold (VT), an increase in the number of PCs and/or a decrease of eigenvalues of PC1 (t = 2.95; p = 0.01; d = 1.08) was found in Test 2 compared to Test 1. Moreover, entropy was significantly higher (Z = 2.33; p = 0.02; d = 1.43) in the last test. In conclusion, despite the fact that no significant differences were observed in the conventionally explored maximal performance and physiological variables (Wmax, VO2 max, and VT) between tests, a reduction of CRC was observed in Test 2. These results emphasize the interest of CRC evaluation in
Polishing Difficult-To-Reach Cavities
Malinzak, R. Michael; Booth, Gary N.
1990-01-01
Springy abrasive tool used to finish surfaces of narrow cavities made by electrical-discharge machining. Robot arm moves vibrator around perimeters of cavities, polishing walls of cavities as it does so. Tool needed because such cavities inaccessible or at least difficult to reach with most surface-finishing tools.
REACH. Electricity Units, Post-Secondary.
Smith, Gene; And Others
As a part of the REACH (Refrigeration, Electro-Mechanical, Air-Conditioning, Heating) electromechanical cluster, this postsecondary student manual contains individualized instructional units in the area of electricity. The instructional units focus on electricity fundamentals, electric motors, electrical components, and controls and installation.…
Reliability of the Advanced REACH Tool (ART)
Schinkel, J.; Fransman, W.; McDonnell, P.E.; Entink, R.K.; Tielemans, E.; Kromhout, H.
2014-01-01
Objectives: The aim of this study was to assess the reliability of the Advanced REACH Tool (ART) by (i) studying interassessor agreement of the resulting exposure estimates generated by the ART mechanistic model, (ii) studying interassessor agreement per model parameters of the ART mechanistic model
Reliability of the Advanced REACH Tool (ART)
Schinkel, J.; Fransman, W.; McDonnell, P.E.; Entink, R.K.; Tielemans, E.; Kromhout, H.
2014-01-01
Objectives: The aim of this study was to assess the reliability of the Advanced REACH Tool (ART) by (i) studying interassessor agreement of the resulting exposure estimates generated by the ART mechanistic model, (ii) studying interassessor agreement per model parameters of the ART mechanistic
Guiding Warfare to Reach Sustainable Peace
Vestenskov, David; Drewes, Line
The conference report Guiding Warfare to Reach Sustainable Peace constitutes the primary outcome of the conference It is based on excerpts from the conference presenters and workshop discussions. Furthermore, the report contains policy recommendations and key findings, with the ambition of develo...
ATLAS Barrel Toroid magnet reached nominal field
2006-01-01
Â OnÂ 9 November the barrel toroid magnet reached its nominal field of 4 teslas, with an electrical current of 21 000 amperes (21 kA) passing through the eight superconducting coils as shown on this graph
Science Experiments: Reaching Out to Our Users
Nolan, Maureen; Tschirhart, Lori; Wright, Stephanie; Barrett, Laura; Parsons, Matthew; Whang, Linda
2008-01-01
As more users access library services remotely, it has become increasingly important for librarians to reach out to their user communities and promote the value of libraries. Convincing the faculty and students in the sciences of the value of libraries and librarians can be a particularly "hard sell" as more and more of their primary…
The REACH Youth Program Learning Toolkit
Sierra Health Foundation, 2011
2011-01-01
Believing in the value of using video documentaries and data as learning tools, members of the REACH technical assistance team collaborated to develop this toolkit. The learning toolkit was designed using and/or incorporating components of the "Engaging Youth in Community Change: Outcomes and Lessons Learned from Sierra Health Foundation's…
Cardiac Function in Patients with Early Cirrhosis during Maximal Beta-Adrenergic Drive
Krag, Aleksander; Bendtsen, Flemming; Dahl, Emilie Kristine
2014-01-01
with cirrhosis and controls had an equal stress response, the heart rate and ejection fraction increased similarly and maximal heart rate was reached in all. At rest CO was higher in Child B patients than controls. During maximal stress, Child B patients had higher CO (10.6±2.7 vs. 8.0±1.8 L/min), left ventricle...... A and B cirrhosis (9 with non-alcoholic cirrhosis) and 7 matched controls were included. We used cardiac magnetic resonance imaging to assess left ventricular volumes and cardiac output (CO) at rest and during maximal heart rate induced by increasing dosages of dobutamine and atropine. RESULTS: Patients...... stress induced by dobutamine is normal. With progression of the disease, the mass of the heart increases along with increase in cardiac volumes....
Several topics in complex variables
Smit, I.M.
2015-01-01
This thesis is based on three articles in the field of Several Complex Variables. The first article, which is joint work with M. El Kadiri, defines and studies the concept of maximality for plurifinely plurisubharmonic functions. Its main result is that a finite plurifinely plurisubharmonic function
Profit maximization, industry structure, and competition: A critique of neoclassical theory
Keen, Steve; Standish, Russell
2006-10-01
Neoclassical economics has two theories of competition between profit-maximizing firms-Marshallian and Cournot-Nash-that start from different premises about the degree of strategic interaction between firms, yet reach the same result, that market price falls as the number of firms in an industry increases. The Marshallian argument is strictly false. We integrate the different premises, and establish that the optimal level of strategic interaction between competing firms is zero. Simulations support our analysis and reveal intriguing emergent behaviors.
Postactivation Potentiation Biases Maximal Isometric Strength Assessment
Leonardo Coelho Rabello Lima
2014-01-01
Full Text Available Postactivation potentiation (PAP is known to enhance force production. Maximal isometric strength assessment protocols usually consist of two or more maximal voluntary isometric contractions (MVCs. The objective of this study was to determine if PAP would influence isometric strength assessment. Healthy male volunteers (n=23 performed two five-second MVCs separated by a 180-seconds interval. Changes in isometric peak torque (IPT, time to achieve it (tPTI, contractile impulse (CI, root mean square of the electromyographic signal during PTI (RMS, and rate of torque development (RTD, in different intervals, were measured. Significant increases in IPT (240.6 ± 55.7 N·m versus 248.9 ± 55.1 N·m, RTD (746 ± 152 N·m·s−1versus 727 ± 158 N·m·s−1, and RMS (59.1 ± 12.2% RMSMAX versus 54.8 ± 9.4% RMSMAX were found on the second MVC. tPTI decreased significantly on the second MVC (2373 ± 1200 ms versus 2784 ± 1226 ms. We conclude that a first MVC leads to PAP that elicits significant enhancements in strength-related variables of a second MVC performed 180 seconds later. If disconsidered, this phenomenon might bias maximal isometric strength assessment, overestimating some of these variables.
Maximizing versus satisficing: happiness is a matter of choice.
Schwartz, Barry; Ward, Andrew; Monterosso, John; Lyubomirsky, Sonja; White, Katherine; Lehman, Darrin R
2002-11-01
Can people feel worse off as the options they face increase? The present studies suggest that some people--maximizers--can. Study 1 reported a Maximization Scale, which measures individual differences in desire to maximize. Seven samples revealed negative correlations between maximization and happiness, optimism, self-esteem, and life satisfaction, and positive correlations between maximization and depression, perfectionism, and regret. Study 2 found maximizers less satisfied than nonmaximizers (satisficers) with consumer decisions, and more likely to engage in social comparison. Study 3 found maximizers more adversely affected by upward social comparison. Study 4 found maximizers more sensitive to regret and less satisfied in an ultimatum bargaining game. The interaction between maximizing and choice is discussed in terms of regret, adaptation, and self-blame.
Cycle-maximal triangle-free graphs
Durocher, Stephane; Gunderson, David S.; Li, Pak Ching
2015-01-01
Abstract We conjecture that the balanced complete bipartite graph K ⌊ n / 2 ⌋ , ⌈ n / 2 ⌉ contains more cycles than any other n -vertex triangle-free graph, and we make some progress toward proving this. We give equivalent conditions for cycle-maximal triangle-free graphs; show bounds...... on the numbers of cycles in graphs depending on numbers of vertices and edges, girth, and homomorphisms to small fixed graphs; and use the bounds to show that among regular graphs, the conjecture holds. We also consider graphs that are close to being regular, with the minimum and maximum degrees differing...
ON THE SPACES OF THE MAXIMAL POINTS
梁基华; 刘应明
2003-01-01
For a continuous domain D, some characterization that the convex powerdomain CD is adomain hull of Max(CD) is given in terms of compact subsets of D. And in this case, it isproved that the set of the maximal points Max(CD) of CD with the relative Scott topology ishomeomorphic to the set of all Scott compact subsets of Max(D) with the topology induced bythe Hausdorff metric derived from a metric on Max(D) when Max(D) is metrizable.
Understanding of English Contracts though Relation Maxims
XU Chi-ying; JIANG Li-hui
2013-01-01
Contract is the legal evidence of the concerning parties of business. And this lead to its unique characteristics:technical terms, archaism, borrowed words, juxtaposition, and abbreviation. The understanding of contracts is of vital importance for each party, because it concerns the share of interests. In order to avoid ambiguity that some words or sentence in English contracts may lead to, and achieve“best relevance and least effort”of communication, this paper, by applying relation maxim, deeply analyze how to understand English contracts though selection of words, modification, the complexity and simplicity of sentence.
Maximizing policy learning in international committees
Nedergaard, Peter
2007-01-01
, this article demonstrates that valuable lessons can be learned about policy learning, in practice and theoretically, by analysing the cooperation in the OMC committees. Using the Advocacy Coalition Framework as the starting point of analysis, 15 hypotheses on policy learning are tested. Among other things......, it is concluded that in order to maximize policy learning in international committees, empirical data should be made available to committees and provided by sources close to the participants (i.e. the Commission). In addition, the work in the committees should be made prestigious in order to attract well...
Does workplace health promotion reach shift workers?
Nabe-Nielsen, Kirsten; Garde, Anne Helene; Clausen, Thomas;
2015-01-01
OBJECTIVES: One reason for health disparities between shift and day workers may be that workplace health promotion does not reach shift workers to the same extent as it reaches day workers. This study aimed to investigate the association between shift work and the availability of and participation...... in workplace health promotion. METHODS: We used cross-sectional questionnaire data from a large representative sample of all employed people in Denmark. We obtained information on the availability of and participation in six types of workplace health promotion. We also obtained information on working hours, ie......). RESULTS: In the general working population, fixed evening and fixed night workers, and employees working variable shifts including night work reported a higher availability of health promotion, while employees working variable shifts without night work reported a lower availability of health promotion...
Olefins and chemical regulation in Europe: REACH.
Penman, Mike; Banton, Marcy; Erler, Steffen; Moore, Nigel; Semmler, Klaus
2015-11-05
REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) is the European Union's chemical regulation for the management of risk to human health and the environment (European Chemicals Agency, 2006). This regulation entered into force in June 2007 and required manufacturers and importers to register substances produced in annual quantities of 1000 tonnes or more by December 2010, with further deadlines for lower tonnages in 2013 and 2018. Depending on the type of registration, required information included the substance's identification, the hazards of the substance, the potential exposure arising from the manufacture or import, the identified uses of the substance, and the operational conditions and risk management measures applied or recommended to downstream users. Among the content developed to support this information were Derived No-Effect Levels or Derived Minimal Effect Levels (DNELs/DMELs) for human health hazard assessment, Predicted No Effect Concentrations (PNECs) for environmental hazard assessment, and exposure scenarios for exposure and risk assessment. Once registered, substances may undergo evaluation by the European Chemicals Agency (ECHA) or Member State authorities and be subject to requests for additional information or testing as well as additional risk reduction measures. To manage the REACH registration and related activities for the European olefins and aromatics industry, the Lower Olefins and Aromatics REACH Consortium was formed in 2008 with administrative and technical support provided by Penman Consulting. A total of 135 substances are managed by this group including 26 individual chemical registrations (e.g. benzene, 1,3-butadiene) and 13 categories consisting of 5-26 substances. This presentation will describe the content of selected registrations prepared for 2010 in addition to the significant post-2010 activities. Beyond REACH, content of the registrations may also be relevant to other European activities, for
Distance Reached in the Anteromedial Reach Test as a Function of Learning and Leg Length
Bent, Nicholas P.; Rushton, Alison B.; Wright, Chris C.; Batt, Mark E.
2012-01-01
The Anteromedial Reach Test (ART) is a new outcome measure for assessing dynamic knee stability in anterior cruciate ligament-injured patients. The effect of learning and leg length on distance reached in the ART was examined. Thirty-two healthy volunteers performed 15 trials of the ART on each leg. There was a moderate correlation (r = 0.44-0.50)…
An information-theoretic analysis of return maximization in reinforcement learning.
Iwata, Kazunori
2011-12-01
We present a general analysis of return maximization in reinforcement learning. This analysis does not require assumptions of Markovianity, stationarity, and ergodicity for the stochastic sequential decision processes of reinforcement learning. Instead, our analysis assumes the asymptotic equipartition property fundamental to information theory, providing a substantially different view from that in the literature. As our main results, we show that return maximization is achieved by the overlap of typical and best sequence sets, and we present a class of stochastic sequential decision processes with the necessary condition for return maximization. We also describe several examples of best sequences in terms of return maximization in the class of stochastic sequential decision processes, which satisfy the necessary condition.
Maximal subbundles, quot schemes, and curve counting
Gillam, W D
2011-01-01
Let $E$ be a rank 2, degree $d$ vector bundle over a genus $g$ curve $C$. The loci of stable pairs on $E$ in class $2[C]$ fixed by the scaling action are expressed as products of $\\Quot$ schemes. Using virtual localization, the stable pairs invariants of $E$ are related to the virtual intersection theory of $\\Quot E$. The latter theory is extensively discussed for an $E$ of arbitrary rank; the tautological ring of $\\Quot E$ is defined and is computed on the locus parameterizing rank one subsheaves. In case $E$ has rank 2, $d$ and $g$ have opposite parity, and $E$ is sufficiently generic, it is known that $E$ has exactly $2^g$ line subbundles of maximal degree. Doubling the zero section along such a subbundle gives a curve in the total space of $E$ in class $2[C]$. We relate this count of maximal subbundles with stable pairs/Donaldson-Thomas theory on the total space of $E$. This endows the residue invariants of $E$ with enumerative significance: they actually \\emph{count} curves in $E$.
Maximal coherence in a generic basis
Yao, Yao; Dong, G. H.; Ge, Li; Li, Mo; Sun, C. P.
2016-12-01
Since quantum coherence is an undoubted characteristic trait of quantum physics, the quantification and application of quantum coherence has been one of the long-standing central topics in quantum information science. Within the framework of a resource theory of quantum coherence proposed recently, a fiducial basis should be preselected for characterizing the quantum coherence in specific circumstances, namely, the quantum coherence is a basis-dependent quantity. Therefore, a natural question is raised: what are the maximum and minimum coherences contained in a certain quantum state with respect to a generic basis? While the minimum case is trivial, it is not so intuitive to verify in which basis the quantum coherence is maximal. Based on the coherence measure of relative entropy, we indicate the particular basis in which the quantum coherence is maximal for a given state, where the Fourier matrix (or more generally, complex Hadamard matrices) plays a critical role in determining the basis. Intriguingly, though we can prove that the basis associated with the Fourier matrix is a stationary point for optimizing the l1 norm of coherence, numerical simulation shows that it is not a global optimal choice.
Hand preferences in preschool children: Reaching, pointing and symbolic gestures.
Cochet, Hélène; Centelles, Laurie; Jover, Marianne; Plachta, Suzy; Vauclair, Jacques
2015-01-01
Manual asymmetries emerge very early in development and several researchers have reported a significant right-hand bias in toddlers although this bias fluctuates depending on the nature of the activity being performed. However, little is known about the further development of asymmetries in preschoolers. In this study, patterns of hand preference were assessed in 50 children aged 3-5 years for different activities, including reaching movements, pointing gestures and symbolic gestures. Contrary to what has been reported in children before 3 years of age, we did not observe any difference in the mean handedness indices obtained in each task. Moreover, the asymmetry of reaching was found to correlate with that of pointing gestures, but not with that of symbolic gestures. In relation to the results reported in infants and adults, this study may help deciphering the mechanisms controlling the development of handedness by providing measures of manual asymmetries in an age range that has been so far rather neglected.
Lamothe, Alain R.
2014-01-01
This article investigates the possibility that e-journal collections can reach a maximum size that satisfies long-term patron needs without further significant expansion. The study included collection and usage data taken from 2000 to 2013. In terms of the e-journal collection, the occurrence of a maximal mass appears to be very real. The…
Lamothe, Alain R.
2014-01-01
This article investigates the possibility that e-journal collections can reach a maximum size that satisfies long-term patron needs without further significant expansion. The study included collection and usage data taken from 2000 to 2013. In terms of the e-journal collection, the occurrence of a maximal mass appears to be very real. The…
Maximal lattice free bodies, test sets and the Frobenius problem
Jensen, Anders Nedergaard; Lauritzen, Niels; Roune, Bjarke Hammersholt
Maximal lattice free bodies are maximal polytopes without interior integral points. Scarf initiated the study of maximal lattice free bodies relative to the facet normals in a fixed matrix. In this paper we give an efficient algorithm for computing the maximal lattice free bodies of an integral...... method is inspired by the novel algorithm by Einstein, Lichtblau, Strzebonski and Wagon and the Groebner basis approach by Roune....
Maximizing scientific knowledge from randomized clinical trials
Gustafsson, Finn; Atar, Dan; Pitt, Bertram;
2010-01-01
Trialists have an ethical and financial responsibility to plan and conduct clinical trials in a manner that will maximize the scientific knowledge gained from the trial. However, the amount of scientific information generated by randomized clinical trials in cardiovascular medicine is highly...... variable. Generation of trial databases and/or biobanks originating in large randomized clinical trials has successfully increased the knowledge obtained from those trials. At the 10th Cardiovascular Trialist Workshop, possibilities and pitfalls in designing and accessing clinical trial databases were......, in particular with respect to collaboration with the trial sponsor and to analytic pitfalls. The advantages of creating screening databases in conjunction with a given clinical trial are described; and finally, the potential for posttrial database studies to become a platform for training young scientists...
Characterizing maximally singular phase-space distributions
Sperling, J.
2016-07-01
Phase-space distributions are widely applied in quantum optics to access the nonclassical features of radiations fields. In particular, the inability to interpret the Glauber-Sudarshan distribution in terms of a classical probability density is the fundamental benchmark for quantum light. However, this phase-space distribution cannot be directly reconstructed for arbitrary states, because of its singular behavior. In this work, we perform a characterization of the Glauber-Sudarshan representation in terms of distribution theory. We address important features of such distributions: (i) the maximal degree of their singularities is studied, (ii) the ambiguity of representation is shown, and (iii) their dual space for nonclassicality tests is specified. In this view, we reconsider the methods for regularizing the Glauber-Sudarshan distribution for verifying its nonclassicality. This treatment is supported with comprehensive examples and counterexamples.
Maximization of eigenvalues using topology optimization
Pedersen, Niels Leergaard
2000-01-01
Topology optimization is used to optimize the eigenvalues of plates. The results are intended especially for MicroElectroMechanical Systems (MEMS) but call be seen as more general. The problem is not formulated as a case of reinforcement of an existing structure, so there is a problem related...... to localized modes in low density areas. The topology optimization problem is formulated using the SIMP method. Special attention is paid to a numerical method for removing localized eigenmodes in low density areas. The method is applied to numerical examples of maximizing the first eigenfrequency, One example...... is a practical MEMS application; a probe used in an Atomic Force Microscope (AFM). For the AFM probe the optimization is complicated by a constraint on the stiffness and constraints on higher order eigenvalues....
Reflection Quasilattices and the Maximal Quasilattice
Boyle, Latham
2016-01-01
We introduce the concept of a {\\it reflection quasilattice}, the quasiperiodic generalization of a Bravais lattice with irreducible reflection symmetry. Among their applications, reflection quasilattices are the reciprocal (i.e. Bragg diffraction) lattices for quasicrystals and quasicrystal tilings, such as Penrose tilings, with irreducible reflection symmetry and discrete scale invariance. In a follow-up paper, we will show that reflection quasilattices can be used to generate tilings in real space with properties analogous to those in Penrose tilings, but with different symmetries and in various dimensions. Here we prove that reflection quasilattices only exist in dimensions two, three and four, and we prove that there is a unique reflection quasilattice in dimension four: the "maximal reflection quasilattice" in terms of dimensionality and symmetry. We further show that, unlike crystallographic Bravais lattices, all reflection quasilattices are invariant under rescaling by certain discrete scale factors. W...
Distributed Maximality based CTL Model Checking
Djamel Eddine Saidouni
2010-05-01
Full Text Available In this paper we investigate an approach to perform a distributed CTL Model checker algorithm on a network of workstations using Kleen three value logic, the state spaces is partitioned among the network nodes, We represent the incomplete state spaces as a Maximality labeled Transition System MLTS which are able to express true concurrency. we execute in parallel the same algorithm in each node, for a certain property on an incomplete MLTS , this last compute the set of states which satisfy or which if they fail are assigned the value .The third value mean unknown whether true or false because the partial state space lacks sufficient information needed for a precise answer concerning the complete state space .To solve this problem each node exchange the information needed to conclude the result about the complete state space. The experimental version of the algorithm is currently being implemented using the functional programming language Erlang.
Evolution of correlated multiplexity through stability maximization
Dwivedi, Sanjiv K
2016-01-01
Investigating relation between various structural patterns found in real-world networks and stability of underlying systems is crucial to understand importance and evolutionary origin of such patterns. We evolve multiplex networks, comprising of anti-symmetric couplings in one layer, depicting predator-prey relation, and symmetric couplings in the other, depicting mutualistic (or competitive) relation, based on stability maximization through the largest eigenvalue. We find that the correlated multiplexity emerges as evolution progresses. The evolved values of the correlated multiplexity exhibit a dependence on the inter-link coupling strength. Furthermore, the inter-layer coupling strength governs the evolution of disassortativity property in the individual layers. We provide analytical understanding to these findings by considering star like networks in both the layers. The model and tools used here are useful for understanding the principles governing the stability as well as importance of such patterns in ...
Witten spinors on maximal, conformally flat hypersurfaces
Frauendiener, Jörg; Szabados, László B
2011-01-01
The boundary conditions that exclude zeros of the solutions of the Witten equation (and hence guarantee the existence of a 3-frame satisfying the so-called special orthonormal frame gauge conditions) are investigated. We determine the general form of the conformally invariant boundary conditions for the Witten equation, and find the boundary conditions that characterize the constant and the conformally constant spinor fields among the solutions of the Witten equations on compact domains in extrinsically and intrinsically flat, and on maximal, intrinsically globally conformally flat spacelike hypersurfaces, respectively. We also provide a number of exact solutions of the Witten equation with various boundary conditions (both at infinity and on inner or outer boundaries) that single out nowhere vanishing spinor fields on the flat, non-extreme Reissner--Nordstr\\"om and Brill--Lindquist data sets. Our examples show that there is an interplay between the boundary conditions, the global topology of the hypersurface...
Greedy Maximal Scheduling in Wireless Networks
Li, Qiao
2010-01-01
In this paper we consider greedy scheduling algorithms in wireless networks, i.e., the schedules are computed by adding links greedily based on some priority vector. Two special cases are considered: 1) Longest Queue First (LQF) scheduling, where the priorities are computed using queue lengths, and 2) Static Priority (SP) scheduling, where the priorities are pre-assigned. We first propose a closed-form lower bound stability region for LQF scheduling, and discuss the tightness result in some scenarios. We then propose an lower bound stability region for SP scheduling with multiple priority vectors, as well as a heuristic priority assignment algorithm, which is related to the well-known Expectation-Maximization (EM) algorithm. The performance gain of the proposed heuristic algorithm is finally confirmed by simulations.
Dispatch Scheduling to Maximize Exoplanet Detection
Johnson, Samson; McCrady, Nate; MINERVA
2016-01-01
MINERVA is a dedicated exoplanet detection telescope array using radial velocity measurements of nearby stars to detect planets. MINERVA will be a completely robotic facility, with a goal of maximizing the number of exoplanets detected. MINERVA requires a unique application of queue scheduling due to its automated nature and the requirement of high cadence observations. A dispatch scheduling algorithm is employed to create a dynamic and flexible selector of targets to observe, in which stars are chosen by assigning values through a weighting function. I designed and have begun testing a simulation which implements the functions of a dispatch scheduler and records observations based on target selections through the same principles that will be used at the commissioned site. These results will be used in a larger simulation that incorporates weather, planet occurrence statistics, and stellar noise to test the planet detection capabilities of MINERVA. This will be used to heuristically determine an optimal observing strategy for the MINERVA project.
A New Biflavone from Selaginella pulvinata Maxim
XU Kang-Ping; XU Zhi; DENG Yin-Hua; LI Fu-Shuang; ZHOU Ying-Jun; HU Gao-Yun; TAN Gui-Shan
2003-01-01
@@ Selaginella pulvinata Maxim. distributes all over the country of China and is used for the treatment for haemor rhage. [1] We studied on the chemical constituents of S. pulvinata in order to find the active compounds. Dried stems and leaves of S. pulvinata (6.5 kg) were extracted with 70% ethanol twice. The extract was evaporated under vacuum and than suspended in water, extracted with petroleum and EtOAc sequentially. The EtOAc extract was chromatographed on silica gel, eluted with CHCl3-MeOH. As a result, a novel biflavone, named pulvinatabiflavone, was obtained from fractions 75 ～ 78. Its structure was determined on the basis of spectroscopic analysis as 5,5″, 4′″ trihydroxy-7,7″-dimethoxy-[4′-O-6″]-biflavone (compound 1).
Maximally reliable Markov chains under energy constraints.
Escola, Sean; Eisele, Michael; Miller, Kenneth; Paninski, Liam
2009-07-01
Signal-to-noise ratios in physical systems can be significantly degraded if the outputs of the systems are highly variable. Biological processes for which highly stereotyped signal generations are necessary features appear to have reduced their signal variabilities by employing multiple processing steps. To better understand why this multistep cascade structure might be desirable, we prove that the reliability of a signal generated by a multistate system with no memory (i.e., a Markov chain) is maximal if and only if the system topology is such that the process steps irreversibly through each state, with transition rates chosen such that an equal fraction of the total signal is generated in each state. Furthermore, our result indicates that by increasing the number of states, it is possible to arbitrarily increase the reliability of the system. In a physical system, however, an energy cost is associated with maintaining irreversible transitions, and this cost increases with the number of such transitions (i.e., the number of states). Thus, an infinite-length chain, which would be perfectly reliable, is infeasible. To model the effects of energy demands on the maximally reliable solution, we numerically optimize the topology under two distinct energy functions that penalize either irreversible transitions or incommunicability between states, respectively. In both cases, the solutions are essentially irreversible linear chains, but with upper bounds on the number of states set by the amount of available energy. We therefore conclude that a physical system for which signal reliability is important should employ a linear architecture, with the number of states (and thus the reliability) determined by the intrinsic energy constraints of the system.
Napa River Restoration Project: Rutherford Reach Completion and Oakville to Oak Knoll Reach
Information about the SFBWQP Napa River Restoration Project: Rutherford Reach Completion/Oakville to Oak Knoll, part of an EPA competitive grant program to improve SF Bay water quality focused on restoring impaired waters and enhancing aquatic resources.
Wyse, Adam E.; Babcock, Ben
2016-01-01
A common suggestion made in the psychometric literature for fixed-length classification tests is that one should design tests so that they have maximum information at the cut score. Designing tests in this way is believed to maximize the classification accuracy and consistency of the assessment. This article uses simulated examples to illustrate…
From entropy-maximization to equality-maximization: Gauss, Laplace, Pareto, and Subbotin
Eliazar, Iddo
2014-12-01
The entropy-maximization paradigm of statistical physics is well known to generate the omnipresent Gauss law. In this paper we establish an analogous socioeconomic model which maximizes social equality, rather than physical disorder, in the context of the distributions of income and wealth in human societies. We show that-on a logarithmic scale-the Laplace law is the socioeconomic equality-maximizing counterpart of the physical entropy-maximizing Gauss law, and that this law manifests an optimized balance between two opposing forces: (i) the rich and powerful, striving to amass ever more wealth, and thus to increase social inequality; and (ii) the masses, struggling to form more egalitarian societies, and thus to increase social equality. Our results lead from log-Gauss statistics to log-Laplace statistics, yield Paretian power-law tails of income and wealth distributions, and show how the emergence of a middle-class depends on the underlying levels of socioeconomic inequality and variability. Also, in the context of asset-prices with Laplace-distributed returns, our results imply that financial markets generate an optimized balance between risk and predictability.
THE EFFECTS MAXIMAL AND SUB MAXIMAL AEROBIC EXERCISE ON THE BRONCHOSPASM INDICES IN NON ATHLETIC
Amir GANJİ
2012-08-01
Full Text Available Background: Exercise-induced bronchospasm (EIB is a transient airway obstruction that occurs during and after the exercise. Exercise-induced bronchospasm is observed in healthy individuals as well as the asthmatic and allergic rhinitis patients. Research question: The study compared the effects of one session of submaximal aerobic exercise and a maximal one on the prevalence of exercise-induced bronchospasm in non-athletic students. Type of study: An experimental study, using human subjects, was designed. Methods: 20 non-athletic male students participated in two sessions of aerobic exercise. The prevalence of EIB was investigated among them. The criteria for assessing exercise-induced bronchospasm were ≥10% fall in FEV1, ≥15% fall in FEF25-75%, or ≥25% fall in PEFR. Results: The results revealed that the maximal exercise did not affect FEF25-75% and PEF, but it led to a meaningful reduction in FEV1. Contrarily, the submaximal exercise affected none of these indices. That is, in both protocols the same result was obtained for PEF and FEF25-75. Moreover, the prevalence of EIB was 15% in the submaximal exercise and 20% in the maximal one. Actually, this difference was significant. Conclusion: This study demonstrated that in contrast to the subjects who performed submaximal exercise, those who participated in the maximal protocol showed more changes in the pulmonary function indices and the prevalence of EIB was greater among them.
Maximal elements of non necessarily acyclic binary relations
Josep Enric Peris Ferrando; Begoña Subiza Martínez
1992-01-01
The existence of maximal elements for binary preference relations is analyzed without imposing transitivity or convexity conditions. From each preference relation a new acyclic relation is defined in such a way that some maximal elements of this new relation characterize maximal elements of the original one. The result covers the case whereby the relation is acyclic.
Optimized Superconducting Nanowire Single Photon Detectors to Maximize Absorptance
Csete, Maria; Szenes, Andras; Banhelyi, Balazs; Csendes, Tibor; Szabo, Gabor
2015-01-01
Dispersion characteristics of four types of superconducting nanowire single photon detectors, nano-cavity-array- (NCA-), nano-cavity-deflector-array- (NCDA-), nano-cavity-double-deflector-array- (NCDDA-) and nano-cavity-trench-array- (NCTA-) integrated (I-A-SNSPDs) devices was optimized in three periodicity intervals commensurate with half-, three-quarter- and one SPP wavelength. The optimal configurations capable of maximizing NbN absorptance correspond to periodicity dependent tilting in S-orientation (90{\\deg} azimuthal orientation). In NCAI-A-SNSPDs absorptance maxima are reached at the plasmonic Brewster angle (PBA) due to light tunneling. The absorptance maximum is attained in a wide plasmonic-pass-band in NCDAI_1/2*lambda-A, inside a flat-plasmonic-pass-band in NCDAI_3/4*lambda-A and inside a narrow plasmonic-band in NCDAI_lambda-A. In NCDDAI_1/2*lambda-A bands of strongly-coupled cavity and plasmonic modes cross, in NCDDAI_3/4*lambda-A an inverted-plasmonic-band-gap develops, while in NCDDAI_lambda-A ...
Defining a controller architecture for the Long-Reach Manipulator
Ford, W.E. [Sandia National Labs., Albuquerque, NM (United States). Intelligent Systems Dept. III
1994-06-01
To draft a procurement specification for the Long-Reach Manipulator (LRM), the benefits and limitations of the various robotic control system architectures available need to be determined. This report identifies and describes the advantages and potential disadvantages of using an open control system versus a closed (or proprietary) system, focusing on integration of interfaces for sensors, end effectors, tooling, and operator interfaces. In addition, the various controls methodologies of several recent systems are described. Finally, the reasons behind the recommendation to procure an open control system are discussed.
Community Detection via Maximization of Modularity and Its Variants
Chen, Mingming; Szymanski, Boleslaw K
2015-01-01
In this paper, we first discuss the definition of modularity (Q) used as a metric for community quality and then we review the modularity maximization approaches which were used for community detection in the last decade. Then, we discuss two opposite yet coexisting problems of modularity optimization: in some cases, it tends to favor small communities over large ones while in others, large communities over small ones (so called the resolution limit problem). Next, we overview several community quality metrics proposed to solve the resolution limit problem and discuss Modularity Density (Qds) which simultaneously avoids the two problems of modularity. Finally, we introduce two novel fine-tuned community detection algorithms that iteratively attempt to improve the community quality measurements by splitting and merging the given network community structure. The first of them, referred to as Fine-tuned Q, is based on modularity (Q) while the second one is based on Modularity Density (Qds) and denoted as Fine-tu...
Retinal Microaneursym Detection using Maximally Stable External Region Algorithm
Diana Tri Susetianingtias
2016-10-01
Full Text Available The growth of diabetics’ worldwide increased drastically. Diabetic can cause blindness due to retinopathy diabetic. Often the patients of retinopathy diabetic do not experience the sign and the symptoms at early stage of their symptoms, even in the severe stages where the bleeding start to occur. One indicator of patients that has diabetic retinopathy can be seen from the blood vessel that experienced microaneurysm and hemorrhage due to a swelling blood vessels in the retina. The study in this paper will implement the Maximally Stable External Region (MSER algorithm to detect microaneursym. Microaneursym is one of the main indicators that causes retinopathy diabetic. This study uses HRF dataset. The results are expected to improve the accuracy microaneursym detection.
Accurate and efficient maximal ball algorithm for pore network extraction
Arand, Frederick; Hesser, Jürgen
2017-04-01
The maximal ball (MB) algorithm is a well established method for the morphological analysis of porous media. It extracts a network of pores and throats from volumetric data. This paper describes structural modifications to the algorithm, while the basic concepts are preserved. Substantial improvements to accuracy and efficiency are achieved as follows: First, all calculations are performed on a subvoxel accurate distance field, and no approximations to discretize balls are made. Second, data structures are simplified to keep memory usage low and improve algorithmic speed. Third, small and reasonable adjustments increase speed significantly. In volumes with high porosity, memory usage is improved compared to classic MB algorithms. Furthermore, processing is accelerated more than three times. Finally, the modified MB algorithm is verified by extracting several network properties from reference as well as real data sets. Runtimes are measured and compared to literature.
Hazard and risk assessment of teratogenic chemicals under REACH.
Prutner, Wiebke
2013-01-01
In 2007, a new European chemicals legislation was implemented: Regulation (EC) No. 1907/2006, also known as "REACH." It obliges companies to take the main responsibility for the valid information on the safe use of the chemicals they manufacture and/or place on the European market. So they must, for example, register their chemicals at the European Chemicals Agency (ECHA) and submit extensive substance-related registration dossiers containing information on the substances' intrinsic hazardous properties and documentation of their risk assessment. REACH regulates the registration and evaluation process as well as the authorization and restriction procedure. In addition, classification, labeling, and packaging of chemicals apply in accordance with Regulation (EC) No. 1272/2008 ("CLP Regulation"). It implements almost completely the provisions of the United Nations Globally Harmonised System of Classification and Labelling of Chemicals (UN GHS) into European legislation and will fully replace the Dangerous Substances Directive (67/548/EEC) and the Dangerous Preparations Directive (1999/45/EC) by 2015. According to both the old and the new classification system, teratogenic chemicals are classified as developmental toxicants, with developmental toxicity falling within the hazard class of reproductive toxicity. REACH as well as the CLP Regulation provide several procedures in which reproductive toxicants take a special position because their harmful effects are considered particularly serious. Teratogenic substances are not explicitly named by these legal texts but, as they constitute as developmental toxicants a hazard differentiation of reproductive toxicity, they are implicitly always included by the provisions.
Reach and get capability in a computing environment
Bouchard, Ann M [Albuquerque, NM; Osbourn, Gordon C [Albuquerque, NM
2012-06-05
A reach and get technique includes invoking a reach command from a reach location within a computing environment. A user can then navigate to an object within the computing environment and invoke a get command on the object. In response to invoking the get command, the computing environment is automatically navigated back to the reach location and the object copied into the reach location.
Maximizing as a predictor of job satisfaction and performance: A tale of three scales
Nicole M. Giacopelli
2013-07-01
Full Text Available Research on individual differences in maximizing (versus satisficing has recently proliferated in the Judgment and Decision Making literature, and high scores on this construct have been linked to lower life satisfaction as well as, in some cases, to worse decision-making performance. The current study exported this construct to the organizational domain and evaluated the utility of the three most widely used measures of maximizing in predicting several criteria of interest to organizational researchers: job satisfaction, intentions to quit the organization, performance in the job role, and income. Moreover, this study used relative weight analyses to determine the relative importance of maximizing and two dispositional variables (conscientiousness and core self-evaluations that are traditionally used to predict these criteria in the organizational literature. Results indicate that relationships between maximizing and these criteria are influenced by the way in which maximizing is measured. Yet, regardless of how it is measured, maximizing is not a particularly strong predictor of these criteria compared to traditional organizational predictors. Limitations and future research directions are discussed.
Maximizing the Economic Benefits of a Multi-Spectral Mission
Kamoun, P.; Martimort, Ph.
Several multi-spectral Space missions have been proposed worldwide to meet the requirements of various applications with hopes of substantial return on investment. However experience has shown that up till today, with very few exceptions, most have not reached expectations and several multi-spectral projects are even staying only at the prospective stage. In this paper the results of a thorough analysis of the requirements of several key thematic domains will be presented ( in particular vegetation monitoring, geology, oceanography, urbanism, ... ). This analysis will be followed by the identification of optimum system specifications to establish a commercially viable system. A description of the technical characteristcs of the optimum system in terms of mission, satellite, platform, instrument and ground segment will then be given. Finally a treatment of the business case will be shown and its economic benefits will be qualitatively and quantitatively indicated. The relationship between such a program and its counterparts worldwide will be explored to identify redundancies or synergies.
Reaching Consensus by Allowing Moments of Indecision
Svenkeson, A.; Swami, A.
2015-10-01
Group decision-making processes often turn into a drawn out and costly battle between two opposing subgroups. Using analytical arguments based on a master equation description of the opinion dynamics occurring in a three-state model of cooperatively interacting units, we show how the capability of a social group to reach consensus can be enhanced when there is an intermediate state for indecisive individuals to pass through. The time spent in the intermediate state must be relatively short compared to that of the two polar states in order to create the beneficial effect. Furthermore, the cooperation between individuals must not be too low, as the benefit to consensus is possible only when the cooperation level exceeds a specific threshold. We also discuss how zealots, agents that remain in one state forever, can affect the consensus among the rest of the population by counteracting the benefit of the intermediate state or making it virtually impossible for an opposition to form.
Morphodynamics of a pseudomeandering gravel bar reach
Bartholdy, J.; Billi, P.
2002-01-01
A large number of rivers in Tuscany have channel planforms, which are neither straight nor what is usually understood as meandering. In the typical case, they consist of an almost straight, slightly incised main channel fringed with large lateral bars and lunate-shaped embayments eroded into the former flood plain. In the past, these rivers have not been recognised as an individual category and have often been considered to be either braided or meandering. It is suggested here that this type of river planform be termed pseudomeandering. A typical pseudomeandering river (the Cecina River) is described and analysed to investigate the main factors responsible for producing this channel pattern. A study reach (100×300 m) was surveyed in detail and related to data on discharge, channel changes after floods and grain-size distribution of bed sediments. During 18 months of topographic monitoring, the inner lateral bar in the study reach expanded and migrated towards the concave outer bank which, concurrently, retreated by as much as 25 m. A sediment balance was constructed to analyse bar growth and bank retreat in relation to sediment supply and channel morphology. The conditions necessary to maintain the pseudomeandering morphology of these rivers by preventing them from developing a meandering planform, are discussed and interpreted as a combination of a few main factors such as the flashy character of floods, sediment supply (influenced by both natural processes and human impact), the morphological effects of discharges with contrasting return intervals and the short duration of flood events. Finally, the channel response to floods with variable sediment transport capacity (represented by bed shear stress) is analysed using a simple model. It is demonstrated that bend migration is associated with moderate floods while major floods are responsible for the development of chute channels, which act to suppress bend growth and maintain the low sinuosity configuration of
Solving Maximal Clique Problem through Genetic Algorithm
Rajawat, Shalini; Hemrajani, Naveen; Menghani, Ekta
2010-11-01
Genetic algorithm is one of the most interesting heuristic search techniques. It depends basically on three operations; selection, crossover and mutation. The outcome of the three operations is a new population for the next generation. Repeating these operations until the termination condition is reached. All the operations in the algorithm are accessible with today's molecular biotechnology. The simulations show that with this new computing algorithm, it is possible to get a solution from a very small initial data pool, avoiding enumerating all candidate solutions. For randomly generated problems, genetic algorithm can give correct solution within a few cycles at high probability.
Maximization Paradox: Result of Believing in an Objective Best.
Luan, Mo; Li, Hong
2017-05-01
The results from four studies provide reliable evidence of how beliefs in an objective best influence the decision process and subjective feelings. A belief in an objective best serves as the fundamental mechanism connecting the concept of maximizing and the maximization paradox (i.e., expending great effort but feeling bad when making decisions, Study 1), and randomly chosen decision makers operate similar to maximizers once they are manipulated to believe that the best is objective (Studies 2A, 2B, and 3). In addition, the effect of a belief in an objective best on the maximization paradox is moderated by the presence of a dominant option (Study 3). The findings of this research contribute to the maximization literature by demonstrating that believing in an objective best leads to the maximization paradox. The maximization paradox is indeed the result of believing in an objective best.
EXPLANATORY VARIANCE IN MAXIMAL OXYGEN UPTAKE
Jacalyn J. Robert McComb
2006-06-01
Full Text Available The purpose of this study was to develop a prediction equation that could be used to estimate maximal oxygen uptake (VO2max from a submaximal water running protocol. Thirty-two volunteers (n =19 males, n = 13 females, ages 18 - 24 years, underwent the following testing procedures: (a a 7-site skin fold assessment; (b a land VO2max running treadmill test; and (c a 6 min water running test. For the water running submaximal protocol, the participants were fitted with an Aqua Jogger Classic Uni-Sex Belt and a Polar Heart Rate Monitor; the participants' head, shoulders, hips and feet were vertically aligned, using a modified running/bicycle motion. A regression model was used to predict VO2max. The criterion variable, VO2max, was measured using open-circuit calorimetry utilizing the Bruce Treadmill Protocol. Predictor variables included in the model were percent body fat (% BF, height, weight, gender, and heart rate following a 6 min water running protocol. Percent body fat accounted for 76% (r = -0.87, SEE = 3.27 of the variance in VO2max. No other variables significantly contributed to the explained variance in VO2max. The equation for the estimation of VO2max is as follows: VO2max ml.kg-1·min-1 = 56.14 - 0.92 (% BF.
Reflection quasilattices and the maximal quasilattice
Boyle, Latham; Steinhardt, Paul J.
2016-08-01
We introduce the concept of a reflection quasilattice, the quasiperiodic generalization of a Bravais lattice with irreducible reflection symmetry. Among their applications, reflection quasilattices are the reciprocal (i.e., Bragg diffraction) lattices for quasicrystals and quasicrystal tilings, such as Penrose tilings, with irreducible reflection symmetry and discrete scale invariance. In a follow-up paper, we will show that reflection quasilattices can be used to generate tilings in real space with properties analogous to those in Penrose tilings, but with different symmetries and in various dimensions. Here we explain that reflection quasilattices only exist in dimensions two, three, and four, and we prove that there is a unique reflection quasilattice in dimension four: the "maximal reflection quasilattice" in terms of dimensionality and symmetry. Unlike crystallographic Bravais lattices, all reflection quasilattices are invariant under rescaling by certain discrete scale factors. We tabulate the complete set of scale factors for all reflection quasilattices in dimension d >2 , and for all those with quadratic irrational scale factors in d =2 .
Viral quasispecies assembly via maximal clique enumeration.
Töpfer, Armin; Marschall, Tobias; Bull, Rowena A; Luciani, Fabio; Schönhuth, Alexander; Beerenwinkel, Niko
2014-03-01
Virus populations can display high genetic diversity within individual hosts. The intra-host collection of viral haplotypes, called viral quasispecies, is an important determinant of virulence, pathogenesis, and treatment outcome. We present HaploClique, a computational approach to reconstruct the structure of a viral quasispecies from next-generation sequencing data as obtained from bulk sequencing of mixed virus samples. We develop a statistical model for paired-end reads accounting for mutations, insertions, and deletions. Using an iterative maximal clique enumeration approach, read pairs are assembled into haplotypes of increasing length, eventually enabling global haplotype assembly. The performance of our quasispecies assembly method is assessed on simulated data for varying population characteristics and sequencing technology parameters. Owing to its paired-end handling, HaploClique compares favorably to state-of-the-art haplotype inference methods. It can reconstruct error-free full-length haplotypes from low coverage samples and detect large insertions and deletions at low frequencies. We applied HaploClique to sequencing data derived from a clinical hepatitis C virus population of an infected patient and discovered a novel deletion of length 357±167 bp that was validated by two independent long-read sequencing experiments. HaploClique is available at https://github.com/armintoepfer/haploclique. A summary of this paper appears in the proceedings of the RECOMB 2014 conference, April 2-5.
Network channel allocation and revenue maximization
Hamalainen, Timo; Joutsensalo, Jyrki
2002-09-01
This paper introduces a model that can be used to share link capacity among customers under different kind of traffic conditions. This model is suitable for different kind of networks like the 4G networks (fast wireless access to wired network) to support connections of given duration that requires a certain quality of service. We study different types of network traffic mixed in a same communication link. A single link is considered as a bottleneck and the goal is to find customer traffic profiles that maximizes the revenue of the link. Presented allocation system accepts every calls and there is not absolute blocking, but the offered data rate/user depends on the network load. Data arrival rate depends on the current link utilization, user's payment (selected CoS class) and delay. The arrival rate is (i) increasing with respect to the offered data rate, (ii) decreasing with respect to the price, (iii) decreasing with respect to the network load, and (iv) decreasing with respect to the delay. As an example, explicit formula obeying these conditions is given and analyzed.
Evolution of correlated multiplexity through stability maximization
Dwivedi, Sanjiv K.; Jalan, Sarika
2017-02-01
Investigating the relation between various structural patterns found in real-world networks and the stability of underlying systems is crucial to understand the importance and evolutionary origin of such patterns. We evolve multiplex networks, comprising antisymmetric couplings in one layer depicting predator-prey relationship and symmetric couplings in the other depicting mutualistic (or competitive) relationship, based on stability maximization through the largest eigenvalue of the corresponding adjacency matrices. We find that there is an emergence of the correlated multiplexity between the mirror nodes as the evolution progresses. Importantly, evolved values of the correlated multiplexity exhibit a dependence on the interlayer coupling strength. Additionally, the interlayer coupling strength governs the evolution of the disassortativity property in the individual layers. We provide analytical understanding to these findings by considering starlike networks representing both the layers. The framework discussed here is useful for understanding principles governing the stability as well as the importance of various patterns in the underlying networks of real-world systems ranging from the brain to ecology which consist of multiple types of interaction behavior.
Viral quasispecies assembly via maximal clique enumeration.
Armin Töpfer
2014-03-01
Full Text Available Virus populations can display high genetic diversity within individual hosts. The intra-host collection of viral haplotypes, called viral quasispecies, is an important determinant of virulence, pathogenesis, and treatment outcome. We present HaploClique, a computational approach to reconstruct the structure of a viral quasispecies from next-generation sequencing data as obtained from bulk sequencing of mixed virus samples. We develop a statistical model for paired-end reads accounting for mutations, insertions, and deletions. Using an iterative maximal clique enumeration approach, read pairs are assembled into haplotypes of increasing length, eventually enabling global haplotype assembly. The performance of our quasispecies assembly method is assessed on simulated data for varying population characteristics and sequencing technology parameters. Owing to its paired-end handling, HaploClique compares favorably to state-of-the-art haplotype inference methods. It can reconstruct error-free full-length haplotypes from low coverage samples and detect large insertions and deletions at low frequencies. We applied HaploClique to sequencing data derived from a clinical hepatitis C virus population of an infected patient and discovered a novel deletion of length 357±167 bp that was validated by two independent long-read sequencing experiments. HaploClique is available at https://github.com/armintoepfer/haploclique. A summary of this paper appears in the proceedings of the RECOMB 2014 conference, April 2-5.
Maximal respiratory pressure in healthy Japanese children
Tagami, Miki; Okuno, Yukako; Matsuda, Tadamitsu; Kawamura, Kenta; Shoji, Ryosuke; Tomita, Kazuhide
2017-01-01
[Purpose] Normal values for respiratory muscle pressures during development in Japanese children have not been reported. The purpose of this study was to investigate respiratory muscle pressures in Japanese children aged 3–12 years. [Subjects and Methods] We measured respiratory muscle pressure values using a manovacuometer without a nose clip, with subjects in a sitting position. Data were collected for ages 3–6 (Group I: 68 subjects), 7–9 (Group II: 86 subjects), and 10–12 (Group III: 64 subjects) years. [Results] The values for respiratory muscle pressures in children were significantly higher with age in both sexes, and were higher in boys than in girls. Correlation coefficients were significant at values of 0.279 to 0.471 for each gender relationship between maximal respiratory pressure and age, height, and weight, respectively. [Conclusion] In this study, we showed pediatric respiratory muscle pressure reference value for each age. In the present study, values for respiratory muscle pressures were lower than Brazilian studies. This suggests that differences in respiratory muscle pressures vary with ethnicity. PMID:28356644
Maximizing exosome colloidal stability following electroporation.
Hood, Joshua L; Scott, Michael J; Wickline, Samuel A
2014-03-01
Development of exosome-based semisynthetic nanovesicles for diagnostic and therapeutic purposes requires novel approaches to load exosomes with cargo. Electroporation has previously been used to load exosomes with RNA. However, investigations into exosome colloidal stability following electroporation have not been considered. Herein, we report the development of a unique trehalose pulse media (TPM) that minimizes exosome aggregation following electroporation. Dynamic light scattering (DLS) and RNA absorbance were employed to determine the extent of exosome aggregation and electroextraction post electroporation in TPM compared to common PBS pulse media or sucrose pulse media (SPM). Use of TPM to disaggregate melanoma exosomes post electroporation was dependent on both exosome concentration and electric field strength. TPM maximized exosome dispersal post electroporation for both homogenous B16 melanoma and heterogeneous human serum-derived populations of exosomes. Moreover, TPM enabled heavy cargo loading of melanoma exosomes with 5nm superparamagnetic iron oxide nanoparticles (SPION5) while maintaining original exosome size and minimizing exosome aggregation as evidenced by transmission electron microscopy. Loading exosomes with SPION5 increased exosome density on sucrose gradients. This provides a simple, label-free means of enriching exogenously modified exosomes and introduces the potential for MRI-driven theranostic exosome investigations in vivo.
Continental reach: The Westcoast Energy story
Newman, P. C.
2002-07-01
A historical account is given of the spectacular success that was Westcoast Energy Inc., a Canadian natural gas giant that charted a wilderness pipeline from natural gas fields in Canada's sub-arctic solitude. The beginning of the company is traced to an event in 1934 when near the bank of the Pouce Coupe River, close to the Alberta-British Columbia border, Frank McMahon, a solitary wildcatter and the eventual founder of the company, first sighted the fiery inferno of a runaway wildcat well, drilled by geologists of the Imperial Oil Company during their original search for the Canadian petroleum basin's motherlode. It was on this occasion in 1934 that McMahon first conceived a geological profile that connected the gas-bearing sandstone of Pouce Coupe with the reservoir rock of the biggest natural gas field of Alberta, and a pipeline from this sandstone storehouse across the rugged heart of British Columbia to Vancouver, and south into the United States. It took the better part of a quarter century to realize the dream of that pipeline which, in due course, turned out to be only the first step towards reaching the top rank of Canadian corporations in operational and financial terms, and becoming one of only a handful in terms of a story that became a Canadian corporate legend. By chronicling the lives and contributions of the company's founder and senior officials over the years, the book traces the company's meteoric rise from a gleam in its founder's eye to a cautious regional utility, and to the aggressive Canadian adventurer that went on to burst the boundaries of its Pacific Coast world, until the continental reach of its operations and interests run from Canada's Pacific shoreline to its Atlantic basins and Mexico's Campeche Bay to Alaska's Prudhoe Bay. The company's independent existence came to an end in 2002 when Westcoast Energy, by then a $15 billion operation, was acquired by Duke Energy Limited of North
Holographic CFTs on maximally symmetric spaces: Correlators, integral transforms, and applications
Hinterbichler, Kurt; Stokes, James; Trodden, Mark
2015-09-01
We study one- and two-point functions of conformal field theories (CFTs) on spaces of maximal symmetry with and without boundaries and investigate their spectral representations. Integral transforms are found, relating the spectral decomposition to renormalized position-space correlators. Several applications are presented, including the holographic boundary CFTs as well as spacelike boundary CFTs, which provide realizations of the pseudoconformal universe.
Important ATLAS Forward Calorimeter Milestone Reached
Loch, P.
The ATLAS Forward Calorimeter working group has reached an important milestone in the production of their detectors. The mechanical assembly of the first electromagnetic module (FCal1C) has been completed at the University of Arizona on February 25, 2002, only ten days after the originally scheduled date. The photo shows the University of Arizona FCal group in the clean room, together with the assembled FCal1C module. The module consists of a stack of 18 round copper plates, each about one inch thick. Each plate is about 90 cm in diameter, and has 12260 precision-drilled holes in it, to accommodate the tube/rod electrode assembly. The machining of the plates, which was done at the Science Technology Center (STC) at Carleton University, Ottawa, Canada, required high precision to allow for easy insertion of the electrode copper tube. The plates have been carefully cleaned at the University of Arizona, to remove any machining residue and metal flakes. This process alone took about eleven weeks. Exactly 122...
LEP Dismantling Reaches Half-Way Stage
2001-01-01
LEP's last superconducting module leaves its home port... Just seven months into the operation, LEP dismantling is forging ahead. Two of the eight arcs which form the tunnel have already been emptied and the last of the accelerator's radiofrequency (RF) cavities has just been raised to the surface. The 160 people working on LEP dismantling have reason to feel pleased with their progress. All of the accelerator's 72 superconducting RF modules have already been brought to the surface, with the last one being extracted on 2nd May. This represents an important step in the dismantling process, as head of the project, John Poole, explains. 'This was the most delicate part of the project, because the modules are very big and they could only come out at one place', he says. The shaft at point 1.8 through which the RF cavity modules pass is 18 metres in diameter, while each module is 11.5 metres long. Some modules had to travel more than 10 kilometres to reach the shaft. ... is lifted up the PM 1.8 shaft, after a m...
CAST reaches milestone but keeps on searching
CERN Courier (september 2011 issue)
2011-01-01
After eight years of searching for the emission of a dark matter candidate particle, the axion, from the Sun, the CERN Axion Solar Telescope (CAST) has fulfilled its original physics programme. Members of the CAST collaboration in July, together with dipole-based helioscope. CAST, the world’s most sensitive axion helioscope, points a recycled prototype LHC dipole magnet at the Sun at dawn and dusk, looking for the conversion of axions to X-rays. It incorporates four state-of-the-art X-ray detectors: three Micromegas detectors and a pn-CCD imaging camera attached to a focusing X-ray telescope that was recovered from the German space programme (see CERN Courier April 2010). Over the years, CAST has operated with the magnet bores - the location of the axion conversion - in different conditions: first in vacuum, covering axion masses up to 20 meV/c2, and then with a buffer gas (4He and later 3He) at various densities, finally reaching the goal of 1.17 eV/c2 on 22 ...
Media perspective - new opportunities for reaching audiences
Haswell, Katy
2007-08-01
The world of media is experiencing a period of extreme and rapid change with the rise of internet television and the download generation. Many young people no longer watch standard TV. Instead, they go on-line, talking to friends and downloading pictures, videos, music clips to put on their own websites and watch/ listen to on their laptops and mobile phones. Gone are the days when TV controllers determined what you watched and when you watched it. Now the buzzword is IPTV, Internet Protocol Television, with companies such as JOOST offering hundreds of channels on a wide range of subjects, all of which you can choose to watch when and where you wish, on your high-def widescreen with stereo surround sound at home or on your mobile phone on the train. This media revolution is changing the way organisations get their message out. And it is encouraging companies such as advertising agencies to be creative about new ways of accessing audiences. The good news is that we have fresh opportunities to reach young people through internet-based media and material downloaded through tools such as games machines, as well as through the traditional media. And it is important for Europlanet to make the most of these new and exciting developments.
Planning of the Extended Reach well Dieksand 2; Planung der Extended Reach Bohrung Dieksand 2
Frank, U.; Berners, H. [RWE-DEA AG, Hamburg (Germany). Drilling Team Mittelplate und Dieksand; Hadow, A.; Klop, G.; Sickinger, W. [Wintershall AG Erdoelwerke, Barnstdorf (Germany); Sudron, K.
1998-12-31
The Mittelplate oil field is located 7 km offshore the town of Friedrichskoog. Reserves are estimated at 30 million tonnes of oil. At a production rate of 2,500 t/d, it will last about 33 years. The transport capacity of the offshore platform is limited, so that attempts were made to enhance production by constructing the extended reach borehole Dieksand 2. Details are presented. (orig.) [Deutsch] Das Erdoelfeld Mittelplate liegt am suedlichen Rand des Nationalparks Schleswig Holsteinisches Wattenmeer, ca. 7000 m westlich der Ortschaft Friedrichskoog. Die gewinnbaren Reserven betragen ca. 30 Millionen t Oel. Bei einer Foerderkapazitaet von 2.500 t/Tag betraegt die Foerderdauer ca. 33 Jahre. Aufgrund der begrenzten Transportkapazitaeten von der Insel, laesst sich durch zusaetzliche Bohrungen von der kuenstlichen Insel Mittelplate keine entscheidende Erhoehung der Foerderkapazitaet erzielen. Ab Sommer 1996 wurde erstmals die Moeglichkeit der Lagerstaettenerschliessung von Land untersucht. Ein im Mai 1997 in Hamburg etabliertes Drilling Team wurde mit der Aufgabe betraut, die Extended Reach Bohrung Dieksand 2 zu planen und abzuteufen. Die Planungsphasen fuer die Extended Reach Bohrung Dieksand 2 wurden aufgezeigt. Die fuer den Erfolg einer Extended Reach Bohrung wichtigen Planungsparameter wurden erlaeutert. Es wurden Wege gezeigt, wie bei diesem Projekt technische und geologische Risiken in der Planung mit beruecksichtigt und nach Beginn der Bohrung weiter bearbeitet werden koennen. (orig.)
[Severe depression : psychoanalysis].
Bouvet de la Maisonneuve, O
2009-12-01
The indication for psychoanalysis in severe depression is not clear. And yet, demands for this type of intervention are increasing, despite the absence of any form of consensus on the subject. Freud considered depression as a failure of analytical efforts and, based on this observation, revised his theory, in particular to include the notions of narcissism and the death drive. Many analysts have been reluctant to follow his teachings on this last point and provide depressed patients with analytical-type therapies aimed at restoring narcissism. Melanie Klein pushed Freud's ideas about depression even further and brought such therapies back to the heart of analytical practice. Jacques Lacan took the debate to another level by proposing an overhaul of the principles on which analysis has been based. Today, while following certain precautionary rules, true psychoanalyses can be proposed to patients with severe depression, whether of the bipolar, recurring or even neurotic type that can reach this level of severity.
Columbia River Estuary Ecosystem Classification Hydrogeomorphic Reach
Cannon, Charles M.; Ramirez, Mary F.; Heatwole, Danelle W.; Burke, Jennifer L.; Simenstad, Charles A.; O'Connor, Jim E.; Marcoe, Keith
2012-01-01
Estuarine ecosystems are controlled by a variety of processes that operate at multiple spatial and temporal scales. Understanding the hierarchical nature of these processes will aid in prioritization of restoration efforts. This hierarchical Columbia River Estuary Ecosystem Classification (henceforth "Classification") of the Columbia River estuary is a spatial database of the tidally-influenced reaches of the lower Columbia River, the tidally affected parts of its tributaries, and the landforms that make up their floodplains for the 230 kilometers between the Pacific Ocean and Bonneville Dam. This work is a collaborative effort between University of Washington School of Aquatic and Fishery Sciences (henceforth "UW"), U.S. Geological Survey (henceforth "USGS"), and the Lower Columbia Estuary Partnership (henceforth "EP"). Consideration of geomorphologic processes will improve the understanding of controlling physical factors that drive ecosystem evolution along the tidal Columbia River. The Classification is organized around six hierarchical levels, progressing from the coarsest, regional scale to the finest, localized scale: (1) Ecosystem Province; (2) Ecoregion; (3) Hydrogeomorphic Reach; (4) Ecosystem Complex; (5) Geomorphic Catena; and (6) Primary Cover Class. For Levels 4 and 5, we mapped landforms within the Holocene floodplain primarily by visual interpretation of Light Detection and Ranging (LiDAR) topography supplemented with aerial photographs, Natural Resources Conservation Service (NRCS) soils data, and historical maps. Mapped landforms are classified as to their current geomorphic function, the inferred process regime that formed them, and anthropogenic modification. Channels were classified primarily by a set of depth-based rules and geometric relationships. Classification Level 5 floodplain landforms ("geomorphic catenae") were further classified based on multivariate analysis of land-cover within the mapped landform area and attributed as "sub
Parallel explicit and implicit control of reaching.
Pietro Mazzoni
Full Text Available BACKGROUND: Human movement can be guided automatically (implicit control or attentively (explicit control. Explicit control may be engaged when learning a new movement, while implicit control enables simultaneous execution of multiple actions. Explicit and implicit control can often be assigned arbitrarily: we can simultaneously drive a car and tune the radio, seamlessly allocating implicit or explicit control to either action. This flexibility suggests that sensorimotor signals, including those that encode spatially overlapping perception and behavior, can be accurately segregated to explicit and implicit control processes. METHODOLOGY/PRINCIPAL FINDINGS: We tested human subjects' ability to segregate sensorimotor signals to parallel control processes by requiring dual (explicit and implicit control of the same reaching movement and testing for interference between these processes. Healthy control subjects were able to engage dual explicit and implicit motor control without degradation of performance compared to explicit or implicit control alone. We then asked whether segregation of explicit and implicit motor control can be selectively disrupted by studying dual-control performance in subjects with no clinically manifest neurologic deficits in the presymptomatic stage of Huntington's disease (HD. These subjects performed successfully under either explicit or implicit control alone, but were impaired in the dual-control condition. CONCLUSION/SIGNIFICANCE: The human nervous system can exert dual control on a single action, and is therefore able to accurately segregate sensorimotor signals to explicit and implicit control. The impairment observed in the presymptomatic stage of HD points to a possible crucial contribution of the striatum to the segregation of sensorimotor signals to multiple control processes.
O'Neill, Barry J
2011-07-20
Abstract Background Tensioning of anterior cruciate ligament (ACL) reconstruction grafts affects the clinical outcome of the procedure. As yet, no consensus has been reached regarding the optimum initial tension in an ACL graft. Most surgeons rely on the maximal sustained one-handed pull technique for graft tension. We aim to determine if this technique is reproducible from patient to patient. Findings We created a device to simulate ACL reconstruction surgery using Ilizarov components and porcine flexor tendons. Six experienced ACL reconstruction surgeons volunteered to tension porcine grafts using the device to see if they could produce a consistent tension. None of the surgeons involved were able to accurately reproduce graft tension over a series of repeat trials. Conclusions We conclude that the maximal sustained one-handed pull technique of ACL graft tensioning is not reproducible from trial to trial. We also conclude that the initial tension placed on an ACL graft varies from surgeon to surgeon.
Hirpara Kieran M
2011-07-01
Full Text Available Abstract Background Tensioning of anterior cruciate ligament (ACL reconstruction grafts affects the clinical outcome of the procedure. As yet, no consensus has been reached regarding the optimum initial tension in an ACL graft. Most surgeons rely on the maximal sustained one-handed pull technique for graft tension. We aim to determine if this technique is reproducible from patient to patient. Findings We created a device to simulate ACL reconstruction surgery using Ilizarov components and porcine flexor tendons. Six experienced ACL reconstruction surgeons volunteered to tension porcine grafts using the device to see if they could produce a consistent tension. None of the surgeons involved were able to accurately reproduce graft tension over a series of repeat trials. Conclusions We conclude that the maximal sustained one-handed pull technique of ACL graft tensioning is not reproducible from trial to trial. We also conclude that the initial tension placed on an ACL graft varies from surgeon to surgeon.
Stanford, Jack A.; Lorang, Mark N.; Matson, Phillip L. (University of Montana, Flathead Lake Biological Station, Poison, MT)
2002-10-01
The Yakima River system historically produced robust annual runs of chinook, sockeye, chum and coho salmon and steelhead. Many different stocks or life history types existed because the physiography of the basin is diverse, ranging from very dry and hot in the high desert of the lower basin to cold and wet in the Cascade Mountains of the headwaters (Snyder and Stanford 2001). Habitat diversity and life history diversity of salmonids are closely correlated in the Yakima Basin. Moreover, habitat diversity for salmonids and many other fishes maximizes in floodplain reaches of river systems (Ward and Stanford 1995, Independent Scientific Group 2000). The flood plains of Yakima River likely were extremely important for spawning and rearing of anadromous salmonids (Snyder and Stanford 2001). However, Yakima River flood plains are substantially degraded. Primary problems are: revetments that disconnect main and side channel habitats; dewatering associated with irrigation that changes base flow conditions and degrades the shallow-water food web; chemical and thermal pollution that prevents proper maturation of eggs and juveniles; and extensive gravel mining within the floodplain reaches that has severed groundwater-channel connectivity, increased thermal loading and increased opportunities for invasions of nonnative species. The Yakima River is too altered from its natural state to allow anything close to the historical abundance and diversity of anadromous fishes. Habitat loss, overharvest and dam and reservoir passage problems in the mainstem Columbia River downstream of the Yakima, coupled with ocean productivity variation, also are implicated in the loss of Yakima fisheries. Nonetheless, in an earlier analysis, Snyder and Stanford (2001) concluded that a significant amount of physical habitat remains in the five floodplain reaches of the mainstem river because habitat-structuring floods do still occur on the remaining expanses of floodplain environment. Assuming main
Spiking and LFP activity in PRR during symbolically instructed reaches
2011-01-01
The spiking activity in the parietal reach region (PRR) represents the spatial goal of an impending reach when the reach is directed toward or away from a visual object. The local field potentials (LFPs) in this region also represent the reach goal when the reach is directed to a visual object. Thus PRR is a candidate area for reading out a patient's intended reach goals for neural prosthetic applications. For natural behaviors, reach goals are not always based on the location of a visual obj...
Catalan Number and Enumeration of Maximal Outerplanar Graphs
无
2000-01-01
Catalan number is an important class of combinatorial numbers. The maximal outerplanar graphs are important in graph theory. In this paper some formulas to enumerate the numbers of maximal outerplanar graphs by means of the compressing graph and group theory method are given first. Then the relationships between Catalan numbers and the numbers of labeled and unlabeled maximal outerplanar graphs are presented. The computed results verified these formulas.
Maximality-Based Structural Operational Semantics for Petri Nets
Saīdouni, Djamel Eddine; Belala, Nabil; Bouneb, Messaouda
2009-03-01
The goal of this work is to exploit an implementable model, namely the maximality-based labeled transition system, which permits to express true-concurrency in a natural way without splitting actions on their start and end events. One can do this by giving a maximality-based structural operational semantics for the model of Place/Transition Petri nets in terms of maximality-based labeled transition systems structures.
Relative advantage, queue jumping, and welfare maximizing wealth distribution
2006-01-01
Suppose individuals get utilities from the total amount of wealth they hold and from their wealth relative to those immediately below them. This paper studies the distribution of wealth that maximizes an additive welfare function made up of these utilities. It interprets wealth distribution in a control theory framework to show that the welfare maximizing distribution may have unexpected properties. In some circumstances it requires that inequality be maximized at the poorest and richest ends...
Maximizers versus satisficers: Decision-making styles, competence, and outcomes
Parker, Andrew M.; Wändi Bruine de Bruin; Baruch Fischhoff
2007-01-01
Our previous research suggests that people reporting a stronger desire to maximize obtain worse life outcomes (Bruine de Bruin et al., 2007). Here, we examine whether this finding may be explained by the decision-making styles of self-reported maximizers. Expanding on Schwartz et al.\\ (2002), we find that self-reported maximizers are more likely to show problematic decision-making styles, as evidenced by self-reports of less behavioral coping, greater dependence on others when making decision...
Maximally entangled states in pseudo-telepathy games
Mančinska, Laura
2015-01-01
A pseudo-telepathy game is a nonlocal game which can be won with probability one using some finite-dimensional quantum strategy but not using a classical one. Our central question is whether there exist two-party pseudo-telepathy games which cannot be won with probability one using a maximally entangled state. Towards answering this question, we develop conditions under which maximally entangled states suffice. In particular, we show that maximally entangled states suffice for weak projection...
Influence of repeated maximal exercise testing on biomarkers and fatigue in sarcoidosis.
Braam, A W E; de Haan, S N; Vorselaars, A D M; Rijkers, G T; Grutters, J C; van den Elshout, F J J; Korenromp, I H E
2013-10-01
Fatigue in the immune mediated inflammatory disease sarcoidosis is thought to be associated with impaired exercise tolerance. This prospective study assessed fatigue and recuperative capacity after repeated exercise, and examined whether changing concentrations in biomarkers upon exercise are associated with fatigue. Twenty sarcoidosis patients and 10 healthy volunteers performed maximal cardiopulmonary exercise tests on two successive days. Concentrations of cytokines, stress hormones, ACE and CK were assessed before and after the two exercise tests, and 3 days thereafter. All participants completed a sleep diary. Severely fatigued patients showed significant lower VO2 max (p=0.038, p=0.022) and maximal workload (p=0.034, p=0.028) on both exercise tests compared to healthy controls. No impairment of maximal exercise testing was demonstrated during the second cycling test in any group. Fatigue was not correlated with changes in concentrations of biomarkers upon exercise. Severely fatigued patients rated both tests as significantly more fatiguing, and reported significant lower mean subjective night sleeping time during the testing period. Fatigue in sarcoidosis patients cannot be objectified by reduction of exercise capacity after repeated maximal exercise testing, and is not correlated with significant changes in biomarkers. Severe fatigue is only and consistently featured by patient reported outcomes. Copyright © 2013 Elsevier Inc. All rights reserved.
Reaching remote areas in Latin America.
Jaimes, R
1994-01-01
Poor communities in remote and inaccessible areas tend to not only be cut off from family planning education and services, but they are also deprived of basic primary health care services. Efforts to bring family planning to such communities and populations should therefore be linked with other services. The author presents three examples of programs to bring effective family planning services to remote communities in Central and South America. Outside of the municipal center in the Tuxtlas region of Mexico, education and health levels are low and people live according to ancient customs. Ten years ago with the help of MEXFAM, the IPPF affiliate in Mexico, two social promoters established themselves in the town of Catemaco to develop a community program of family planning and health care offering education and prevention to improve the quality of people's lives. Through their health brigades taking health services to towns without an established health center, the program has influenced an estimated 100,000 people in 50 villages and towns. The program also has a clinic. In Guatemala, the Family Welfare Association (APROFAM) gave bicycles to 240 volunteer health care workers to facilitate their outreach work in rural areas. APROFAM since 1988 has operated an integrated program to treat intestinal parasites and promote family planning in San Lucas de Toliman, an Indian town close to Lake Atitlan. Providing health care to more than 10,000 people, the volunteer staff has covered the entire department of Solola, reaching each family in the area. Field educators travel on motorcycles through the rural areas of Guatemala coordinating with the health volunteers the distribution of contraceptives at the community level. The Integrated Project's Clinic was founded in 1992 and currently carries out pregnancy and Pap tests, as well as general lab tests. Finally, Puna is an island in the middle of the Gulf of Guayaquil, Ecuador. Women on the island typically have 10
Sums of magnetic eigenvalues are maximal on rotationally symmetric domains
Laugesen, Richard S; Roy, Arindam
2011-01-01
The sum of the first n energy levels of the planar Laplacian with constant magnetic field of given total flux is shown to be maximal among triangles for the equilateral triangle, under normalization of the ratio (moment of inertia)/(area)^3 on the domain. The result holds for both Dirichlet and Neumann boundary conditions, with an analogue for Robin (or de Gennes) boundary conditions too. The square similarly maximizes the eigenvalue sum among parallelograms, and the disk maximizes among ellipses. More generally, a domain with rotational symmetry will maximize the magnetic eigenvalue sum among all linear images of that domain. These results are new even for the ground state energy (n=1).
Sums of Laplace eigenvalues - rotationally symmetric maximizers in the plane
Laugesen, R S
2010-01-01
The sum of the first $n \\geq 1$ eigenvalues of the Laplacian is shown to be maximal among triangles for the equilateral triangle, maximal among parallelograms for the square, and maximal among ellipses for the disk, provided the ratio $\\text{(area)}^3/\\text{(moment of inertia)}$ for the domain is fixed. This result holds for both Dirichlet and Neumann eigenvalues, and similar conclusions are derived for Robin boundary conditions and Schr\\"odinger eigenvalues of potentials that grow at infinity. A key ingredient in the method is the tight frame property of the roots of unity. For general convex plane domains, the disk is conjectured to maximize sums of Neumann eigenvalues.
Maximal Cohen-Macaulay modules over non-isolated surface singularities and matrix problems
Burban, Igor
2017-01-01
In this article the authors develop a new method to deal with maximal Cohen-Macaulay modules over non-isolated surface singularities. In particular, they give a negative answer on an old question of Schreyer about surface singularities with only countably many indecomposable maximal Cohen-Macaulay modules. Next, the authors prove that the degenerate cusp singularities have tame Cohen-Macaulay representation type. The authors' approach is illustrated on the case of \\mathbb{k} x,y,z/(xyz) as well as several other rings. This study of maximal Cohen-Macaulay modules over non-isolated singularities leads to a new class of problems of linear algebra, which the authors call representations of decorated bunches of chains. They prove that these matrix problems have tame representation type and describe the underlying canonical forms.
A short note on the maximal point-biserial correlation under non-normality.
Cheng, Ying; Liu, Haiyan
2016-11-01
The aim of this paper is to derive the maximal point-biserial correlation under non-normality. Several widely used non-normal distributions are considered, namely the uniform distribution, t-distribution, exponential distribution, and a mixture of two normal distributions. Results show that the maximal point-biserial correlation, depending on the non-normal continuous variable underlying the binary manifest variable, may not be a function of p (the probability that the dichotomous variable takes the value 1), can be symmetric or non-symmetric around p = .5, and may still lie in the range from -1.0 to 1.0. Therefore researchers should exercise caution when they interpret their sample point-biserial correlation coefficients based on popular beliefs that the maximal point-biserial correlation is always smaller than 1, and that the size of the correlation is always further restricted as p deviates from .5. © 2016 The British Psychological Society.
Maximizing Experiential Learning for Student Success
Coker, Jeffrey Scott; Porter, Desiree Jasmine
2015-01-01
Several years ago, Elon University set out to better understand experiential learning on campus. At the time, there was a pragmatic need to collect data that would inform revisions to the core curriculum, including an experiential-learning requirement (ELR) that had been in place since 1994. The question was whether it made sense to raise the…
Public Private Partnerships: Managing Risk, Maximizing Value
Davidson, Steve
2012-01-01
This session will examine current practices in evaluating P3 projects, enabling legislation in Indiana and other states, financing options and appropriate timeframes for engaging concessionaires. Several P3 projects from across North America will be discussed in terms of their successes and failures from the perspective of both owners and concessionaires.
Fluvial geomorphology of the Middle Reach of the Huai River
Bang-yi YU; Peng WU; Jue-yi SUI; Xing-ju YANG; Jin NI
2014-01-01
The Middle Reach of the Huai River (MRHR) flows northeast into the Hongzehu Lake. Before entering the Hongzehu Lake, the Huai River has a braided channel which is shallow and wide, and the riverbed has a negative slope. Based on the characteristics of the MRHR, this river reach can be divided into the following sections: a quasi-straight (or mildly curved) section, a bend section, and a braided section. The majority of the MRHR is quasi-straight. In this paper, several parameters are used to assess the geomorphology of the MRHR. Statistical analyses are performed to establish a relationship between the span length“L”and channel width“B”for different channel patterns. The relationship between the meandering length “S” and bankfull channel width “B” is also derived. Results indicate that the bankfull channel width “B”, the bankfull cross sectional area “A” and the average flow depth“H”are mainly dependent on the dominant discharge in the channel. A relationship is derived that describes the dependency of the curvature radius“R”on the dominant discharge“Q”, water surface slope“J”and the turning angle“α”.
Livestock First Reached Southern Africa in Two Separate Events.
Karim Sadr
Full Text Available After several decades of research on the subject, we now know when the first livestock reached southern Africa but the question of how they got there remains a contentious topic. Debate centres on whether they were brought with a large migration of Khoe-speakers who originated from East Africa; or whether the livestock were traded down-the-line among hunter-gatherer communities; or indeed whether there was a long history of diverse small scale population movements in this part of the world, one or more of which 'infiltrated' livestock into southern Africa. A new analysis of the distribution of stone toolkits from a sizeable sample of sub-equatorial African Later Stone Age sites, coupled with existing knowledge of the distribution of the earliest livestock remains and ceramics vessels, has allowed us to isolate two separate infiltration events that brought the first livestock into southern Africa just over 2000 years ago; one infiltration was along the Atlantic seaboard and another entered the middle reaches of the Limpopo River Basin. These findings agree well with the latest results of genetic research which together indicate that multiple, small-scale infiltrations probably were responsible for bringing the first livestock into southern Africa.
Observations of improvement of reaching in five subjects with left hemiparesis.
Trombly, C A
1993-01-01
Kinematic analysis and surface electromyography were used to study reaching by five subjects with left hemiparesis as they attempted to touch each of three targets. The targets were placed to require movement within and out of extensor synergy. Each subject was tested five times over a nine week period. Over this time, amplitude of peak velocity and sense of limb position significantly improved in the paretic arms. The increase of amplitude of peak velocity was more strongly related to a decrease in the discontinuity of movement (r = -0.48) than to maximal level of contraction of the prime movers (anterior deltoid: r = 0.25; biceps: r = 0.39). This finding may be a sign of learning or increased maturity of reach. These results, if replicated in a larger sample, would support therapy designed to improve learning of new sensorimotor relationships in the hemiparetic limb.
The “Fallacy” of Maximizing the Geometric Mean in Long Sequences of Investing or Gambling
Samuelson, Paul A.
1971-01-01
Because the outcomes of repeated investments or gambles involve products of variables, authorities have repeatedly been tempted to the belief that, in a long sequence, maximization of the expected value of terminal utility can be achieved or well-approximated by a strategy of maximizing at each stage the geometric mean of outcome (or its equivalent, the expected value of the logarithm of principal plus return). The law of large numbers or of the central limit theorem as applied to the logs can validate the conclusion that a maximum-geometric-mean strategy does indeed make it “virtually certain” that, in a “long” sequence, one will end with a higher terminal wealth and utility. However, this does not imply the false corollary that the geometric-mean strategy is optimal for any finite number of periods, however long, or that it becomes asymptotically a good approximation. As a trivial counter-example, it is shown that for utility proportional to xγ/γ, whenever γ ≠ 0, the geometric strategy is suboptimal for all T and never a good approximation. For utility bounded above, as when γ < 0, the same conclusion holds. If utility is bounded above and finite at zero wealth, no uniform strategy can be optimal, even though it can be that the best uniform strategy will be that of the maximum geometric mean. However, asymptotically the same level of utility can be reached by an infinity of nearby uniform strategies. The true optimum in the bounded case involves nonuniform strategies, usually being more risky than the geometric-mean maximizer's strategy at low wealths and less risky at high wealths. The novel criterion of maximizing the expected average compound return, which asymptotically leads to maximizing of geometric mean, is shown to be arbitrary. PMID:16591949
[How to reach the right size?].
Roisin-Bouffay, Céline; Gomer, Richard H
2004-02-01
Very little is known about how the size of an organism, or a specific tissue in an organism, is regulated. Coordinating and regulating the size of tissues is necessary for proper development, wound healing, and regeneration. Defects in a tissue-size regulation mechanism could lead to birth defects or cancer. In addition, there is a strong psychological aspect to some areas of tissue size regulation, as many cosmetic surgery procedures involve enlarging or reducing the size of some body parts. This review addresses the little bit that we know about size regulation. A key concept is that the size of a tissue is the size of the component cells multiplied by the number of those cells. This breaks the size regulation problem down to two parts. The size of cells can be regulated by nutrient sensing and secreted factors, and may have an upper limit due to an upper limit of a genome's ability to produce mRNA's and thus proteins. To regulate the number of cells in a tissue, there are several simple theoretical models involving secreted factors. In one case, the cells can secrete a characteristic factor and the concentration of the factor will increase with the number of cells secreting it, allowing the tissue to sense its own size. In another scenario, a specific cell secretes a limited amount of a factor necessary for the survival of a target population, and this then limits the size of the target population. There are currently several examples of secreted factors that regulate tissue size, including myostatin, which regulates the amount of muscles, leptin, which regulates adipose tissue, and growth hormone and insulin-like growth factors which regulate total mass. In addition, there are factors such as the found in Dictyostelium that regulate the breakup of a tissue into sub-groups. A better understanding of how these factors regulate size will hopefully allow us to develop new therapeutic procedures to treat birth defects or diseases that affect tissue size.
Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors
Pedro Caruso
2008-01-01
Full Text Available INTRODUCTION: It is known that mechanical ventilation and many of its features may affect the evolution of inspiratory muscle strength during ventilation. However, this evolution has not been described, nor have its predictors been studied. In addition, a probable parallel between inspiratory and limb muscle strength evolution has not been investigated. OBJECTIVE: To describe the variation over time of maximal inspiratory pressure during mechanical ventilation and its predictors. We also studied the possible relationship between the evolution of maximal inspiratory pressure and limb muscle strength. METHODS: A prospective observational study was performed in consecutive patients submitted to mechanical ventilation for > 72 hours. The maximal inspiratory pressure trend was evaluated by the linear regression of the daily maximal inspiratory pressure and a logistic regression analysis was used to look for independent maximal inspiratory pressure trend predictors. Limb muscle strength was evaluated using the Medical Research Council score. RESULTS: One hundred and sixteen patients were studied, forty-four of whom (37.9% presented a decrease in maximal inspiratory pressure over time. The members of the group in which maximal inspiratory pressure decreased underwent deeper sedation, spent less time in pressure support ventilation and were extubated less frequently. The only independent predictor of the maximal inspiratory pressure trend was the level of sedation (OR=1.55, 95% CI 1.003 - 2.408; p = 0.049. There was no relationship between the maximal inspiratory pressure trend and limb muscle strength. CONCLUSIONS: Around forty percent of the mechanically ventilated patients had a decreased maximal inspiratory pressure during mechanical ventilation, which was independently associated with deeper levels of sedation. There was no relationship between the evolution of maximal inspiratory pressure and the muscular strength of the limb.
Study on New Approaches for extended chemical management and REACH
Lee, Jihyun
2014-01-01
For several decades, the use of chemicals has been rapidly increasing and widely spread in our daily life. To cope with this trend, the paradigm of chemical management system has changed: from hazard criteria which is based on their intrinsic hazardous properties, to the actual risk of chemicals...... which is based on both the hazard of the substance and the possible exposure level of human to the substance, and from single substance-oriented to multiple chemical (e.g. mixture toxicity)–oriented management system (EC, 2012; Moeller and Biwer, 2014). This study aims to examine the limitations...... of existing chemical regulations in view of protecting vulnerable populations from “excessive total risk” and to explore the possibilities for improvement. Firstly, the completeness of the REACH exposure scenario was reviewed with the finding that the current scenario does not take into account territorial...
Reaching Rural Canadian Communities in the Yukon and Alberta
Van Laerhoven, Christa L.
2016-10-01
Canada is very large geographically, so many rural communities are very far from major centers. People in such communities are at a severe disadvantage when it comes to in-person interaction with science or scientists because resources tend to be directed at large population centers, where more people can be reached for the same amount of effort. While this geographic distance can be mitigated by doing outreach over the internet, there is at some level no substitute for showing up in person with e.g. meteorites in hand. Due to where various members of my family are located, I have occasion to visit Whitehorse, YT and Andrew, AB (~1.5 hour drive north-east of Edmonton) and have taken advantage of trips to these locations to do astronomy outreach in both schools and public libraries. I will discuss how I arranged school and library visits and general observations from my experience doing outreach in rural Canadian communities.
D2-brane Chern-Simons theories: F-maximization = a-maximization
Fluder, Martin
2015-01-01
We study a system of N D2-branes probing a generic Calabi-Yau three-fold singularity in the presence of a non-zero quantized Romans mass n. We argue that the low-energy effective N = 2 Chern-Simons quiver gauge theory flows to a superconformal fixed point in the IR, and construct the dual AdS_4 solution in massive IIA supergravity. We compute the free energy F of the gauge theory on S^3 using localization. In the large N limit we find F = c(nN)^{1/3}a^{2/3}, where c is a universal constant and a is the a-function of the "parent" four-dimensional N = 1 theory on N D3-branes probing the same Calabi-Yau singularity. It follows that maximizing F over the space of admissible R-symmetries is equivalent to maximizing a for this class of theories. Moreover, we show that the gauge theory result precisely matches the holographic free energy of the supergravity solution, and provide a similar matching of the VEV of a BPS Wilson loop operator.
Detrimental Relations of Maximization with Academic and Career Attitudes
Dahling, Jason J.; Thompson, Mindi N.
2013-01-01
Maximization refers to a decision-making style that involves seeking the single best option when making a choice, which is generally dysfunctional because people are limited in their ability to rationally evaluate all options and identify the single best outcome. The vocational consequences of maximization are examined in two samples, college…
An Overview of Maximal Unitarity at Two Loops
Johansson, Henrik; Larsen, Kasper J.
2012-01-01
We discuss the extension of the maximal-unitarity method to two loops, focusing on the example of the planar double box. Maximal cuts are reinterpreted as contour integrals, with the choice of contour fixed by the requirement that integrals of total derivatives vanish on it. The resulting formulae, like their one-loop counterparts, can be applied either analytically or numerically.
The Negative Consequences of Maximizing in Friendship Selection.
Newman, David B; Schug, Joanna; Yuki, Masaki; Yamada, Junko; Nezlek, John B
2017-02-27
Previous studies have shown that the maximizing orientation, reflecting a motivation to select the best option among a given set of choices, is associated with various negative psychological outcomes. In the present studies, we examined whether these relationships extend to friendship selection and how the number of options for friends moderated these effects. Across 5 studies, maximizing in selecting friends was negatively related to life satisfaction, positive affect, and self-esteem, and was positively related to negative affect and regret. In Study 1, a maximizing in selecting friends scale was created, and regret mediated the relationships between maximizing and well-being. In a naturalistic setting in Studies 2a and 2b, the tendency to maximize among those who participated in the fraternity and sorority recruitment process was negatively related to satisfaction with their selection, and positively related to regret and negative affect. In Study 3, daily levels of maximizing were negatively related to daily well-being, and these relationships were mediated by daily regret. In Study 4, we extended the findings to samples from the U.S. and Japan. When participants who tended to maximize were faced with many choices, operationalized as the daily number of friends met (Study 3) and relational mobility (Study 4), the opportunities to regret a decision increased and further diminished well-being. These findings imply that, paradoxically, attempts to maximize when selecting potential friends is detrimental to one's well-being. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
Haemodynamics during maximal exercise after coronary bypass surgery
P.W.J.C. Serruys (Patrick); M.F. Rousseau (Francois); J. Cosyns; R. Ponlot; L.A. Brasseur; J-M.R. Detry (Jean-Marie)
1978-01-01
textabstractFifty patients underwent an objective measurement of physical working capacity by means of a multistage test of maximally tolerated exertion before and after coronary bypass surgery; 29 patients also had haemodynamic measurements during maximal exercise before and after coronary bypass s
Utility maximization under solvency constraints and unhedgeable risks
T. Kleinow; A. Pelsser
2008-01-01
We consider the utility maximization problem for an investor who faces a solvency or risk constraint in addition to a budget constraint. The investor wishes to maximize her expected utility from terminal wealth subject to a bound on her expected solvency at maturity. We measure solvency using a solv
Detrimental Relations of Maximization with Academic and Career Attitudes
Dahling, Jason J.; Thompson, Mindi N.
2013-01-01
Maximization refers to a decision-making style that involves seeking the single best option when making a choice, which is generally dysfunctional because people are limited in their ability to rationally evaluate all options and identify the single best outcome. The vocational consequences of maximization are examined in two samples, college…
On a discrete version of Tanaka's theorem for maximal functions
Bober, Jonathan; Hughes, Kevin; Pierce, Lillian B
2010-01-01
In this paper we prove a discrete version of Tanaka's Theorem \\cite{Ta} for the Hardy-Littlewood maximal operator in dimension $n=1$, both in the non-centered and centered cases. For the discrete non-centered maximal operator $\\wM $ we prove that, given a function $f: \\Z \\to \\R$ of bounded variation,
Haemodynamics during maximal exercise after coronary bypass surgery
P.W.J.C. Serruys (Patrick); M.F. Rousseau (Francois); J. Cosyns; R. Ponlot; L.A. Brasseur; J-M.R. Detry (Jean-Marie)
1978-01-01
textabstractFifty patients underwent an objective measurement of physical working capacity by means of a multistage test of maximally tolerated exertion before and after coronary bypass surgery; 29 patients also had haemodynamic measurements during maximal exercise before and after coronary bypass
ESTIMATES FOR THE MAXIMAL MULTILINEAR SINGULAR INTEGRAL OPERATORS
Yulan Jiao
2010-01-01
In this paper,some mapping properties are considered for the maximal multilinear singular integral operator whose kernel satisfies certain minimum regularity condition.It is proved that certain uniform local estimate for doubly truncated operators implies the LP(Rn)(1
maximal operator.
Maximally Flat Waveforms Operation of Class-F Power Amplifiers
V. Krizhanovski
2001-04-01
Full Text Available The requirements to output network's impedance on higher harmoniccomponents and appropriate input driving for formation maximally flatwaveforms of drain current and voltage were presented. Using suchwaveforms allows obtaining maximal efficiency and output powercapability of class-F power amplifiers.
Entanglement of Superpositions of Orthogonal Maximally Entangled States
ZHANG Dao-Hua; ZHOU Duan-Lu; FAN Heng
2010-01-01
@@ We study the entanglement properties of the superposed state of orthogonal maximally entangled states.It is shown that the superposed state is maximally entangled and the superposed state is separable.The relation between the superposed state and the mutually unbiased state is discussed.
CHROMATIC NUMBER OF SQUARE OF MAXIMAL OUTERPLANAR GRAPHS
Luo Xiaofang
2007-01-01
Let χ(G2) denote the chromatic number of the square of a maximal outerplanar graph G and Q denote a maximal outerplanar graph obtained by adding three chords and χ(G2) = Δ + 2 if and only if G is Q, where Δ represents the maximum degree of G.
SAR image target segmentation based on entropy maximization and morphology
柏正尧; 刘洲峰; 何佩琨
2004-01-01
Entropy maximization thresholding is a simple, effective image segmentation method. The relation between the histogram entropy and the gray level of an image is analyzed. An approach, which speeds the computation of optimal threshold based on entropy maximization, is proposed. The suggested method has been applied to the synthetic aperture radar (SAR) image targets segmentation. Mathematical morphology works well in reducing the residual noise.
Effect of Age and Other Factors on Maximal Heart Rate.
Londeree, Ben R.; Moeschberger, Melvin L.
1982-01-01
To reduce confusion regarding reported effects of age on maximal exercise heart rate, a comprehensive review of the relevant English literature was conducted. Data on maximal heart rate after exercising with a bicycle, a treadmill, and after swimming were analyzed with regard to physical fitness and to age, sex, and racial differences. (Authors/PP)
Economic interpretation of environmental flow regime downstream diverted river reaches.
Gorla, Lorenzo; Perona, Paolo
2013-04-01
Water demand for hydropower production is increasing together with the consciousness of the importance of riparian ecosystems and biodiversity. Some Cantons in Switzerland and other alpine regions in Austria and in Sud Tirol (Italy) started replacing the inadequate concept of Minimum Flow Requirement (MFR) with a dynamic one, by releasing a fix percentage of the total inflow (e.g. 25 %) to the environment. In the same direction Perona et al. (in revision) mathematically formulated a method particularly suitable for small hydropower plants, handling the environment as a non-traditional water use, which competes with exploitators. This model uses the Principle of Equal Marginal Utility (PEMU) as optimal water allocation rule for generating like-natural flow releases while maximizing the aggregate economic benefit of all uses (Gorla and Perona, in revision). In this paper we show how redistribution policies can be interpreted in terms of PEMU, particularly we focus at traditional water repartition rules, such as the MFR, but also to dynamic ones like proportional redistribution. For the first case we show both ecological and economical arguments suggesting its inappropriateness; in the second case we highlight explicit points of strength and weakness, and suggest ways of improvement. For example the flow release allocation rule can be changed from inflow-independent ones (e.g., proportional redistribution), to inflow-dependent ones (e.g., non-proportional). The latters, having fewer constraints, can generally lead to better both ecological and economical performances. A class of simple functions, based on the PEMU, is then proposed as a suitable solution in run-of-river or small hydropower plants. Each water repartition policy underlies an ecosystem monetization. We explicit the value of the ecosystem health underlying each policy by means of the PEMU under a few assumptions, and discuss how the theoretic efficient redistribution law obtained by our approach is
Glioma Surgery: Technological Advances to Achieve a Maximal Safe Resection.
Altieri, Roberto; Zenga, Francesco; Fontanella, Marco Maria; Cofano, Fabio; Agnoletti, Alessandro; Spena, Giannantonio; Crobeddu, Emanuela; Fornaro, Riccardo; Ducati, Alessandro; Garbossa, Diego
2015-11-01
Glioblastoma multiforme (GBM) is the most frequent primary central nervous system (CNS) tumor. Despite the best treatment and advances in therapy, prognosis remains poor. One of the mainstays of therapy in GBM is surgical excision. Several studies have confirmed that the extent of resection (EOR) positively influences overall survival (OS) in patients with high-grade gliomas (HGGs). A literature search was performed using PubMed to assess the useful neurosurgical tools to achieve the best neurosurgical performance. In order to achieve the major extent of resection, preserving neurological function, many tools are now available, especially neuronavigation, intraoperative fluorescence, intraoperative ultrasound, and neuromonitoring. In addition to the maximal excision of tumor, the neurosurgeon can use photodynamic therapy (PTD) and local drug delivery (LDD) to improve the local control and bridge conventional radio and chemotherapy. EOR improves OS in patients with HGGs. There are technological possibilities for achieving a complete resection preserving neurological function, and it is not acceptable to perform only biopsy of these lesions.
System to maximize inventory performance in a small hospital.
VanDerLinde, L P
1983-01-01
A computerized system to maximize inventory performance in a small hospital is described. An inventory control system, which integrates economic order quantity (EOQ) and ABC inventory models was implemented in a 146-bed hospital. The perpetual inventory control data base, supported by the hospital's mainframe computer, generates monthly inventory statistics that are segregated into A, B, and C reports. Using a hand-held computer that interfaces with the perpetual inventory system, a series of inventory management reports were developed. These reports, which are based on the EOQ model, provide the following information for each drug line item: EOQ, EOQ proposed carrying cost, actual inventory carrying costs, safety stock, order point, average inventory, and the "on hand/on order" point. Several supplemental inventory management reports were also developed. While implementing the computerized inventory system, the pharmacy also changed its purchasing strategy from predominantly direct accounts to a progressive prime-vendor wholesaler. From December 1980 to December 1981, the ABC/EOQ system with progressive prime-vendor involvement essentially doubled total aggregate inventory turnover. A 46.5% reduction in standing inventory levels occurred. The drug cost per line item dispersed remained relatively constant over the one-year period, despite price increases. The application of the computerized ABC/EOQ inventory model to an online perpetual inventory control data base effectively reduced the inventory operation costs.
Paracellular epithelial sodium transport maximizes energy efficiency in the kidney.
Pei, Lei; Solis, Glenn; Nguyen, Mien T X; Kamat, Nikhil; Magenheimer, Lynn; Zhuo, Min; Li, Jiahua; Curry, Joshua; McDonough, Alicia A; Fields, Timothy A; Welch, William J; Yu, Alan S L
2016-07-01
Efficient oxygen utilization in the kidney may be supported by paracellular epithelial transport, a form of passive diffusion that is driven by preexisting transepithelial electrochemical gradients. Claudins are tight-junction transmembrane proteins that act as paracellular ion channels in epithelial cells. In the proximal tubule (PT) of the kidney, claudin-2 mediates paracellular sodium reabsorption. Here, we used murine models to investigate the role of claudin-2 in maintaining energy efficiency in the kidney. We found that claudin-2-null mice conserve sodium to the same extent as WT mice, even during profound dietary sodium depletion, as a result of the upregulation of transcellular Na-K-2Cl transport activity in the thick ascending limb of Henle. We hypothesized that shifting sodium transport to transcellular pathways would lead to increased whole-kidney oxygen consumption. Indeed, compared with control animals, oxygen consumption in the kidneys of claudin-2-null mice was markedly increased, resulting in medullary hypoxia. Furthermore, tubular injury in kidneys subjected to bilateral renal ischemia-reperfusion injury was more severe in the absence of claudin-2. Our results indicate that paracellular transport in the PT is required for efficient utilization of oxygen in the service of sodium transport. We speculate that paracellular permeability may have evolved as a general strategy in epithelial tissues to maximize energy efficiency.
ERF1 -- Enhanced River Reach File 1.2
U.S. Geological Survey, Department of the Interior — U.S. Environmental Protection Agency's River Reach File 1 (RF1)to ensure the hydrologic integrity of the digital reach traces and to quantify the mean water time of...
Berthon, P; Fellmann, N
2002-09-01
The maximal aerobic velocity concept developed since eighties is considered as either the minimal velocity which elicits the maximal aerobic consumption or as the "velocity associated to maximal oxygen consumption". Different methods for measuring maximal aerobic velocity on treadmill in laboratory conditions have been elaborated, but all these specific protocols measure V(amax) either during a maximal oxygen consumption test or with an association of such a test. An inaccurate method presents a certain number of problems in the subsequent use of the results, for example in the elaboration of training programs, in the study of repeatability or in the determination of individual limit time. This study analyzes 14 different methods to understand their interests and limits in view to propose a general methodology for measuring V(amax). In brief, the test should be progressive and maximal without any rest period and of 17 to 20 min total duration. It should begin with a five min warm-up at 60-70% of the maximal aerobic power of the subjects. The beginning of the trial should be fixed so that four or five steps have to be run. The duration of the steps should be three min with a 1% slope and an increasing speed of 1.5 km x h(-1) until complete exhaustion. The last steps could be reduced at two min for a 1 km x h(-1) increment. The maximal aerobic velocity is adjusted in relation to duration of the last step.
Maximization of Growth Rates During Czochralski Pulling
Wargo, M. J.
1984-01-01
It was suggested from theory(1-4) that silicon can be grown from the melt at rates far exceeding the current state of the art. Previous theoretical and experimental investigations which predict maximum rates of pulling during Czochralski growth are reviewed. Several experimental methods are proposed to modify the temperature distribution in a growing crystal to achieve higher rates of pulling. A physical model of a Czochralski crystal of germanium in contact with its melt was used to quantitatively determine, by direct measurement of the axial temperature distribution in the solid, the increase in axial temperature gradients effected by an inverted conical heat reflector located above the melt and coaxially about the physical model. Preliminary results indicate that this is an effective method of increasing the thermal resistance between the hot melt and crucible wall and a growing crystal. Under these conditions the enhancement of the interfacial temperature gradients permit a commensurate increase in the rate of crystal pulling.
Cell Culture Microfluidic Biochips: Experimental Throughput Maximization
Minhass, Wajid Hassan; Pop, Paul; Madsen, Jan
2011-01-01
Microfluidic biochips offer a promising alternative to a conventional biochemical laboratory, integrating all necessary functionalities on-chip in order to perform biochemical applications. Researchers have started to propose computer-aided design tools for the synthesis of such biochips. Our foc...... metaheuristic for experimental design generation for the cell culture microfluidic biochips, and we have evaluated our approach using multiple experimental setups....... in this paper is on the optimization of how a biochemical application is performed on a biochip. In this paper, we consider cell culture biochips, where several cell colonies are exposed to soluble compounds and monitored in real-time to determine the right combination of factors that leads to the desired...
Minetti, Andrea; Hurtado, Northan; Grais, Rebecca F; Ferrari, Matthew
2014-01-15
Current mass vaccination campaigns in measles outbreak response are nonselective with respect to the immune status of individuals. However, the heterogeneity in immunity, due to previous vaccination coverage or infection, may lead to potential bias of such campaigns toward those with previous high access to vaccination and may result in a lower-than-expected effective impact. During the 2010 measles outbreak in Malawi, only 3 of the 8 districts where vaccination occurred achieved a measureable effective campaign impact (i.e., a reduction in measles cases in the targeted age groups greater than that observed in nonvaccinated districts). Simulation models suggest that selective campaigns targeting hard-to-reach individuals are of greater benefit, particularly in highly vaccinated populations, even for low target coverage and with late implementation. However, the choice between targeted and nonselective campaigns should be context specific, achieving a reasonable balance of feasibility, cost, and expected impact. In addition, it is critical to develop operational strategies to identify and target hard-to-reach individuals.
Barene, Svein; Holtermann, Andreas; Oseland, Harald
2016-01-01
lean mass (0.4 kg; P vertical jump height or sit-and-reach flexibility. The present study indicates that workplace-initiated soccer and Zumba exercise may be beneficial for improvement of the neck and trunk strength, which may......This 9-month randomised controlled workplace physical activity trial investigated the effects of soccer and Zumba exercise, respectively, on muscle strength, maximal jump height, sit-and-reach flexibility and postural sway among female workers. A total of 107 female hospital employees aged 25...
Proprioceptive recalibration arises slowly compared to reach adaptation.
Zbib, Basel; Henriques, Denise Y P; Cressman, Erin K
2016-08-01
When subjects reach in a novel visuomotor environment (e.g. while viewing a cursor representing their hand that is rotated from their hand's actual position), they typically adjust their movements (i.e. bring the cursor to the target), thus reducing reaching errors. Additionally, research has shown that reaching with altered visual feedback of the hand results in sensory changes, such that proprioceptive estimates of hand position are shifted in the direction of the visual feedback experienced (Cressman and Henriques in J Neurophysiol 102:3505-3518, 2009). This study looked to establish the time course of these sensory changes. Additionally, the time courses of implicit sensory and motor changes were compared. Subjects reached to a single visual target while seeing a cursor that was either aligned with their hand position (50 trials) or rotated 30° clockwise relative to their hand (150 trials). Reach errors and proprioceptive estimates of felt hand position were assessed following the aligned reach training trials and at seven different times during the rotated reach training trials by having subjects reach to the target without visual feedback, and provide estimates of their hand relative to a visual reference marker, respectively. Results revealed a shift in proprioceptive estimates throughout the rotated reach training trials; however, significant sensory changes were not observed until after 70 trials. In contrast, results showed a greater change in reaches after a limited number of reach training trials with the rotated cursor. These findings suggest that proprioceptive recalibration arises more slowly than reach adaptation.
Reach/frequency for printed media: Personal probabilities or models
Mortensen, Peter Stendahl
2000-01-01
The author evaluates two different ways of estimating reach and frequency of plans for printed media. The first assigns reading probabilities to groups of respondents and calculates reach and frequency by simulation. the second estimates parameters to a model for reach/frequency. It is concluded...
Francica, Juliana V; Heeren, Marcelo V; Tubaldini, Márcio; Sartori, Michelle; Mostarda, Cristiano; Araujo, Rubens C; Irigoyen, Maria-Cláudia; De Angelis, Kátia
2013-06-01
The objective of the present study was to compare cardiovascular and autonomic responses to a mental stress test and to a maximal isometric exercise test between offspring of normotensive (ON, n = 10) and hypertensive parents (OH, n = 10). Subjects underwent a 3-min Stroop Color Word Test and a maximal isometric exercise test performed in an isokinetic dynamometer with continuous RR interval monitoring. At rest, arterial pressure and heart rate were similar between groups, but there was a significant reduction in total RR interval variance (ON: 5933 ± 493 vs. OH: 2967 ± 390 ms(2)) and an increase in low-high frequency components ratio of heart rate variability (ON: 2.3 ± 0.4 vs. OH: 4.6 ± 0.8) in OH group. In the first minute of the mental stress test and after both tests, the OH group presented increased heart rate as compared with the ON group. After both tests, only the ON group presented an increase in sympathetic component, thus reaching resting values similar to those of the OH group. Our data demonstrated increased resting cardiac sympathetic modulation in offspring of hypertensive parents at similar levels to that observed in offspring of normotensive parents after a mental stress test or a maximal isometric exercise test. Additionally, the exacerbated heart rate responses to these physiological tests in OH subjects may be associated with resting autonomic dysfunction, thus reinforcing these evaluations as important tools for detecting early dysfunctions in this genetically predisposed population.
Gil eScaglioni
2016-02-01
Full Text Available This study aimed at testing the hypothesis that differences in neural activation strategy during submaximal but not maximal plantarflexions exist between young and older men. Eleven young men (YM, 26±4 yr and 13 OM (76±3 yr volunteered for the investigation. Maximal voluntary torque (MVT was 38.2%, lower (P<0.001 in OM than in YM, while voluntary activation was equivalent (~97%. The relationship between the interpolated twitch-torque and the voluntary torque (IT-VT relationship was composite (curvilinear+exponential for both age-groups. However, the OM showed accentuated concavity, as attested by the occurrence of the deviation from linearity at a lower contraction intensity (OM: 54.9 vs. YM: 71.9% MVT. In conclusion, ageing does not affect the capacity to fully activate the plantar flexors during maximal performances, but it alters the activation pattern for submaximal levels of effort. The greater age-related concavity of the IT-VT relationship suggests that, during submaximal contractions, OM need to reach a level of activation higher than YM to develop an equivalent relative torque.
Hahn, D; Bakenecker, P; Zinke, F
2016-12-28
Torque production during maximal voluntary explosive contractions is considered to be a functionally more relevant neuromuscular measure than steady-state torque, but little is known about accelerated concentric contractions. This study investigated torque, muscle activity, and fascicle behavior during isometric and fast concentric contractions of quadriceps femoris. Ten participants performed maximal voluntary explosive isometric, isovelocity, and additional concentric knee extensions at angular accelerations ranging from 700 to 4000° s(-2) that resulted in an angular velocity of 300° s(-1) at 40° knee flexion. Concentric torque at 40° knee flexion was corrected for inertia, and the corresponding isometric torque was matched to the time when the target knee angle of 40° was reached during concentric contractions. Electromyography of quadriceps femoris and hamstrings and ultrasound of vastus lateralis were measured to determine muscle activity, fascicle length, and fascicle velocity (FV). The faster the acceleration, the more torque was produced during concentric contractions at 40° knee flexion, which was accompanied by a reduction in FV. In comparison with isometric conditions, concentric quadriceps muscle activity was increased and torque during accelerations ≥3000° s(-2) equaled the time-matched isometric torque. Our results provide novel evidence that acceleration influences torque production during maximal voluntary explosive concentric contractions. This is suggested to be due to series elasticity and reduced force depression.
Inquiry in bibliography some of the bustan`s maxim
sajjad rahmatian
2016-12-01
Full Text Available Sa`di is on of those poets who`s has placed a special position to preaching and guiding the people and among his works, allocated throughout the text of bustan to advice and maxim on legal and ethical various subjects. Surely, sa`di on the way of to compose this work and expression of its moral point, direct or indirect have been affected by some previous sources and possibly using their content. The main purpose of this article is that the pay review of basis and sources of bustan`s maxims and show that sa`di when expression the maxims of this work has been affected by which of the texts and works. For this purpose is tried to with search and research on the resources that have been allocated more or less to the aphorisms, to discover and extract traces of influence sa`di from their moral and didactic content. From the most important the finding of this study can be mentioned that indirect effect of some pahlavi books of maxim (like maxims of azarbad marespandan and bozorgmehr book of maxim and also noted sa`di directly influenced of moral and ethical works of poets and writers before him, and of this, sa`di`s influence from abo- shakur balkhi maxims, ferdowsi and keikavus is remarkable and noteworthy.
Maximal strength training improves cycling economy in competitive cyclists.
Sunde, Arnstein; Støren, Oyvind; Bjerkaas, Marius; Larsen, Morten H; Hoff, Jan; Helgerud, Jan
2010-08-01
The purpose of the present study was to investigate the effect of maximal strength training on cycling economy (CE) at 70% of maximal oxygen consumption (Vo2max), work efficiency in cycling at 70% Vo2max, and time to exhaustion at maximal aerobic power. Responses in 1 repetition maximum (1RM) and rate of force development (RFD) in half-squats, Vo2max, CE, work efficiency, and time to exhaustion at maximal aerobic power were examined. Sixteen competitive road cyclists (12 men and 4 women) were randomly assigned into either an intervention or a control group. Thirteen (10 men and 3 women) cyclists completed the study. The intervention group (7 men and 1 woman) performed half-squats, 4 sets of 4 repetitions maximum, 3 times per week for 8 weeks, as a supplement to their normal endurance training. The control group continued their normal endurance training during the same period. The intervention manifested significant (p < 0.05) improvements in 1RM (14.2%), RFD (16.7%), CE (4.8%), work efficiency (4.7%), and time to exhaustion at pre-intervention maximal aerobic power (17.2%). No changes were found in Vo2max or body weight. The control group exhibited an improvement in work efficiency (1.4%), but this improvement was significantly (p < 0.05) smaller than that in the intervention group. No changes from pre- to postvalues in any of the other parameters were apparent in the control group. In conclusion, maximal strength training for 8 weeks improved CE and efficiency and increased time to exhaustion at maximal aerobic power among competitive road cyclists, without change in maximal oxygen uptake, cadence, or body weight. Based on the results from the present study, we advise cyclists to include maximal strength training in their training programs.
Spiking and LFP activity in PRR during symbolically instructed reaches.
Hwang, Eun Jung; Andersen, Richard A
2012-02-01
The spiking activity in the parietal reach region (PRR) represents the spatial goal of an impending reach when the reach is directed toward or away from a visual object. The local field potentials (LFPs) in this region also represent the reach goal when the reach is directed to a visual object. Thus PRR is a candidate area for reading out a patient's intended reach goals for neural prosthetic applications. For natural behaviors, reach goals are not always based on the location of a visual object, e.g., playing the piano following sheet music or moving following verbal directions. So far it has not been directly tested whether and how PRR represents reach goals in such cognitive, nonlocational conditions, and knowing the encoding properties in various task conditions would help in designing a reach goal decoder for prosthetic applications. To address this issue, we examined the macaque PRR under two reach conditions: reach goal determined by the stimulus location (direct) or shape (symbolic). For the same goal, the spiking activity near reach onset was indistinguishable between the two tasks, and thus a reach goal decoder trained with spiking activity in one task performed perfectly in the other. In contrast, the LFP activity at 20-40 Hz showed small but significantly enhanced reach goal tuning in the symbolic task, but its spatial preference remained the same. Consequently, a decoder trained with LFP activity performed worse in the other task than in the same task. These results suggest that LFP decoders in PRR should take into account the task context (e.g., locational vs. nonlocational) to be accurate, while spike decoders can robustly provide reach goal information regardless of the task context in various prosthetic applications.
Maximizing the Impact of e-Therapy and Serious Gaming: Time for a Paradigm Shift.
Fleming, Theresa M; de Beurs, Derek; Khazaal, Yasser; Gaggioli, Andrea; Riva, Giuseppe; Botella, Cristina; Baños, Rosa M; Aschieri, Filippo; Bavin, Lynda M; Kleiboer, Annet; Merry, Sally; Lau, Ho Ming; Riper, Heleen
2016-01-01
Internet interventions for mental health, including serious games, online programs, and apps, hold promise for increasing access to evidence-based treatments and prevention. Many such interventions have been shown to be effective and acceptable in trials; however, uptake and adherence outside of trials is seldom reported, and where it is, adherence at least, generally appears to be underwhelming. In response, an international Collaboration On Maximizing the impact of E-Therapy and Serious Gaming (COMETS) was formed. In this perspectives' paper, we call for a paradigm shift to increase the impact of internet interventions toward the ultimate goal of improved population mental health. We propose four pillars for change: (1) increased focus on user-centered approaches, including both user-centered design of programs and greater individualization within programs, with the latter perhaps utilizing increased modularization; (2) Increased emphasis on engagement utilizing processes such as gaming, gamification, telepresence, and persuasive technology; (3) Increased collaboration in program development, testing, and data sharing, across both sectors and regions, in order to achieve higher quality, more sustainable outcomes with greater reach; and (4) Rapid testing and implementation, including the measurement of reach, engagement, and effectiveness, and timely implementation. We suggest it is time for researchers, clinicians, developers, and end-users to collaborate on these aspects in order to maximize the impact of e-therapies and serious gaming.
Maximizing the Impact of e-Therapy and Serious Gaming: Time for a Paradigm Shift
Fleming, Theresa M.; de Beurs, Derek; Khazaal, Yasser; Gaggioli, Andrea; Riva, Giuseppe; Botella, Cristina; Baños, Rosa M.; Aschieri, Filippo; Bavin, Lynda M.; Kleiboer, Annet; Merry, Sally; Lau, Ho Ming; Riper, Heleen
2016-01-01
Internet interventions for mental health, including serious games, online programs, and apps, hold promise for increasing access to evidence-based treatments and prevention. Many such interventions have been shown to be effective and acceptable in trials; however, uptake and adherence outside of trials is seldom reported, and where it is, adherence at least, generally appears to be underwhelming. In response, an international Collaboration On Maximizing the impact of E-Therapy and Serious Gaming (COMETS) was formed. In this perspectives’ paper, we call for a paradigm shift to increase the impact of internet interventions toward the ultimate goal of improved population mental health. We propose four pillars for change: (1) increased focus on user-centered approaches, including both user-centered design of programs and greater individualization within programs, with the latter perhaps utilizing increased modularization; (2) Increased emphasis on engagement utilizing processes such as gaming, gamification, telepresence, and persuasive technology; (3) Increased collaboration in program development, testing, and data sharing, across both sectors and regions, in order to achieve higher quality, more sustainable outcomes with greater reach; and (4) Rapid testing and implementation, including the measurement of reach, engagement, and effectiveness, and timely implementation. We suggest it is time for researchers, clinicians, developers, and end-users to collaborate on these aspects in order to maximize the impact of e-therapies and serious gaming. PMID:27148094
Maximizing the impact of e-therapy and serious gaming: Time for a paradigm shift
Theresa M Fleming
2016-04-01
Full Text Available Internet interventions for mental health, including serious games, online programs and apps, hold promise for increasing access to evidence-based treatments and prevention. Many such interventions have been shown to be effective and acceptable in trials; however, uptake and adherence outside of trials is seldom reported, and where it is, adherence at least, generally appears to be underwhelming. In response, an international Collaboration On Maximizing the impact of E-Therapy and Serious Gaming (COMETS was formed. In this perspectives paper, we call for a paradigm shift to increase the impact of internet interventions towards the ultimate goal of improved population mental health. We propose four pillars for change: 1. Increased focus on user-centered approaches, including both user-centered design of programs and greater individualization within programs, with the latter perhaps utilizing increased modulariziation. 2. Increased emphasis on engagement; utilizing processes such as gaming, gamification, telepresence, and persuasive technology. 3. Increased collaboration in program development, testing and data sharing, across both sectors and regions, in order to achieve higher quality, more sustainable outcomes with greater reach. 4. Rapid testing and implementation, including the measurement of reach, engagement and effectiveness, and timely implementation. We suggest it is time for researchers, clinicians, developers and end-users to collaborate on these aspects in order to maximize the impact of e-therapies and serious gaming.
On maximally supersymmetric Yang-Mills theories
Movshev, M
2004-01-01
We consider ten-dimensional supersymmetric Yang-Mills theory (10D SUSY YM theory) and its dimensional reductions, in particular, BFSS and IKKT models. We formulate these theories using algebraic techniques based on application of differential graded Lie algebras and associative algebras as well as of more general objects, L_{\\infty}- and A_{\\infty}- algebras. We show that using pure spinor formulation of 10D SUSY YM theory equations of motion and isotwistor formalism one can interpret these equations as Maurer-Cartan equations for some differential Lie algebra. This statement can be used to write BV action functional of 10D SUSY YM theory in Chern-Simons form. The differential Lie algebra we constructed is closely related to differential associative algebra Omega of (0, k)-forms on some supermanifold; the Lie algebra is tensor product of Omega and matrix algebra . We construct several other algebras that are quasiisomorphic to Omega and, therefore, also can be used to give BV formulation of 10D SUSY YM theory...
The Maximal Graded Left Quotient Algebra of a Graded Algebra
Gonzalo ARANDA PINO; Mercedes SILES MOLINA
2006-01-01
We construct the maximal graded left quotient algebra of every graded algebra A without homogeneous total right zero divisors as the direct limit of graded homomorphisms (of left A-modules)from graded dense left ideals of A into a graded left quotient algebra of A. In the case of a superalgebra,and with some extra hypothesis, we prove that the component in the neutral element of the group of the maximal graded left quotient algebra coincides with the maximal left quotient algebra of the component in the neutral element of the group of the superalgebra.
Maximal regularity of second order delay equations in Banach spaces
无
2010-01-01
We give necessary and sufficient conditions of Lp-maximal regularity(resp.B sp ,q-maximal regularity or F sp ,q-maximal regularity) for the second order delay equations:u″(t)=Au(t) + Gu’t + F u t + f(t), t ∈ [0, 2π] with periodic boundary conditions u(0)=u(2π), u′(0)=u′(2π), where A is a closed operator in a Banach space X,F and G are delay operators on Lp([-2π, 0];X)(resp.Bsp ,q([2π, 0];X) or Fsp,q([-2π, 0;X])).
Building hospital TQM teams: effective polarity analysis and maximization.
Hurst, J B
1996-09-01
Building and maintaining teams require careful attention to and maximization of such polar opposites (¿polarities¿) as individual and team, directive and participatory leadership, task and process, and stability and change. Analyzing systematic elements of any polarity and listing blocks, supports, and flexible ways to maximize it will prevent the negative consequences that occur when treating a polarity like a solvable problem. Flexible, well-timed shifts from pole to pole result in the maximization of upside and minimization of downside consequences.
People believe each other to be selfish hedonic maximizers.
De Vito, Stefania; Bonnefon, Jean-François
2014-10-01
Current computational models of theory of mind typically assume that humans believe each other to selfishly maximize utility, for a conception of utility that makes it indistinguishable from personal gains. We argue that this conception is at odds with established facts about human altruism, as well as the altruism that humans expect from each other. We report two experiments showing that people expect other agents to selfishly maximize their pleasure, even when these other agents behave altruistically. Accordingly, defining utility as pleasure permits us to reconcile the assumption that humans expect each other to selfishly maximize utility with the fact that humans expect each other to behave altruistically.
Lp Estimates of Rough Maximal Functions Along Surfaces with Applications
Ahmad AL-SALMAN; Abdulla M. JARRAH
2016-01-01
In this paper, we study the Lp mapping properties of certain class of maximal oscillatory singular integral operators. We prove a general theorem for a class of maximal functions along surfaces. As a consequence of such theorem, we establish the Lp boundedness of various maximal oscillatory singular integrals provided that their kernels belong to the natural space L log L(Sn−1). Moreover, we highlight some additional results concerning operators with kernels in certain block spaces. The results in this paper substantially improve previously known results.
Changes in context and perception of maximum reaching height.
Wagman, Jeffrey B; Day, Brian M
2014-01-01
Successfully performing a given behavior requires flexibility in both perception and behavior. In particular, doing so requires perceiving whether that behavior is possible across the variety of contexts in which it might be performed. Three experiments investigated how (changes in) context (ie point of observation and intended reaching task) influenced perception of maximum reaching height. The results of experiment 1 showed that perceived maximum reaching height more closely reflected actual reaching ability when perceivers occupied a point of observation that was compatible with that required for the reaching task. The results of experiments 2 and 3 showed that practice perceiving maximum reaching height from a given point of observation improved perception of maximum reaching height from a different point of observation, regardless of whether such practice occurred at a compatible or incompatible point of observation. In general, such findings show bounded flexibility in perception of affordances and are thus consistent with a description of perceptual systems as smart perceptual devices.
Embeddings of maximal tori in classical groups over local and global fields
Bayer-Fluckiger, E.; Lee, T.-Y.; Parimala, R.
2016-08-01
Embeddings of maximal tori in classical groups over fields of characteristic not 2 are the subject matter of several recent papers. The aim of the present paper is to give necessary and sufficient conditions for such an embedding to exist, when the base field is a local field, or the field of real numbers. This completes the results of [3], where a complete criterion is given for the Hasse principle to hold when the base field is a global field.
Maximally entangled state can be a mixed state
Li, Zong-Guo; Fei, Shao-Ming; Fan, Heng; Liu, W M
2009-01-01
We present mixed maximally entangled states in d\\otimes d' (d'\\geq 2d) spaces. This result is beyond the generally accepted fact that all maximally entangled states are pure. These states possess important properties of the pure maximally entangled states in $d\\otimes d$ systems, for example, they can be used as a resource for faithful teleportation, their local distinguishability property is also the same as the pure states case. On the other hand, one advantage of these mixed maximally entangled states is that the decoherence induced by certain noisy quantum channel does not destroy their entanglement. Thus one party of these mixed states can be sent through this channel to arbitrary distance while still keeping them as a valuable resource for quantum information processing. We also propose a scheme to prepare these states and confirm their advantage in NMR physical system.
Groups Satisfying the Maximal Condition on Non-modular Subgroups
Maria De Falco; Carmela Musella
2005-01-01
In this paper, (generalized) soluble groups for which the set of non-modular subgroups verifies the maximal condition and groups for which the set of non-permutable subgroups satisfies the same property are classified.
Maximizing antimalarial efficacy and the importance of dosing strategies
Beeson, James G; Boeuf, Philippe; Fowkes, Freya J I
2015-01-01
.... Without new drugs to replace artemisinins, it is essential to define dosing strategies that maximize therapeutic efficacy, limit the spread of resistance, and preserve the clinical value of ACTs...
Maximal entanglement versus entropy for mixed quantum states
Wei, T C; Goldbart, P M; Kwiat, P G; Munro, W J; Verstraete, F; Wei, Tzu-Chieh; Nemoto, Kae; Goldbart, Paul M.; Kwiat, Paul G.; Munro, William J.; Verstraete, Frank
2003-01-01
Maximally entangled mixed states are those states that, for a given mixedness, achieve the greatest possible entanglement. For two-qubit systems and for various combinations of entanglement and mixedness measures, the form of the corresponding maximally entangled mixed states is determined primarily analytically. As measures of entanglement, we consider entanglement of formation, relative entropy of entanglement, and negativity; as measures of mixedness, we consider linear and von Neumann entropies. We show that the forms of the maximally entangled mixed states can vary with the combination of (entanglement and mixedness) measures chosen. Moreover, for certain combinations, the forms of the maximally entangled mixed states can change discontinuously at a specific value of the entropy.
Maximal induced paths and minimal percolating sets in hypercubes
Anil M. Shende
2015-01-01
Full Text Available For a graph $G$, the \\emph{$r$-bootstrap percolation} process can be described as follows: Start with an initial set $A$ of "infected'' vertices. Infect any vertex with at least $r$ infected neighbours, and continue this process until no new vertices can be infected. $A$ is said to \\emph{percolate in $G$} if eventually all the vertices of $G$ are infected. $A$ is a \\emph{minimal percolating set} in $G$ if $A$ percolates in $G$ and no proper subset of $A$ percolates in $G$. An induced path, $P$, in a hypercube $Q_n$ is maximal if no induced path in $Q_n$ properly contains $P$. Induced paths in hypercubes are also called snakes. We study the relationship between maximal snakes and minimal percolating sets (under 2-bootstrap percolation in hypercubes. In particular, we show that every maximal snake contains a minimal percolating set, and that every minimal percolating set is contained in a maximal snake.
Sensitivity to conversational maxims in deaf and hearing children.
Surian, Luca; Tedoldi, Mariantonia; Siegal, Michael
2010-09-01
We investigated whether access to a sign language affects the development of pragmatic competence in three groups of deaf children aged 6 to 11 years: native signers from deaf families receiving bimodal/bilingual instruction, native signers from deaf families receiving oralist instruction and late signers from hearing families receiving oralist instruction. The performance of these children was compared to a group of hearing children aged 6 to 7 years on a test designed to assess sensitivity to violations of conversational maxims. Native signers with bimodal/bilingual instruction were as able as the hearing children to detect violations that concern truthfulness (Maxim of Quality) and relevance (Maxim of Relation). On items involving these maxims, they outperformed both the late signers and native signers attending oralist schools. These results dovetail with previous findings on mindreading in deaf children and underscore the role of early conversational experience and instructional setting in the development of pragmatics.
Classification of conformal representations induced from the maximal cuspidal parabolic
Dobrev, V. K., E-mail: dobrev@inrne.bas.bg [Scuola Internazionale Superiore di Studi Avanzati (Italy)
2017-03-15
In the present paper we continue the project of systematic construction of invariant differential operators on the example of representations of the conformal algebra induced from the maximal cuspidal parabolic.
dos Santos, Gilberto Monteiro; Montrezol, Fábio Tanil; Pauli, Luciana Santos Souza; Sartori-Cintra, Angélica Rossi; Colantonio, Emilson; Gomes, Ricardo José; Marinho, Rodolfo; de Moura, Leandro Pereira; Pauli, José Rodrigo
2014-01-01
Objective To investigate the effects of a specific protocol of undulatory physical resistance training on maximal strength gains in elderly type 2 diabetics. Methods The study included 48 subjects, aged between 60 and 85 years, of both genders. They were divided into two groups: Untrained Diabetic Elderly (n=19) with those who were not subjected to physical training and Trained Diabetic Elderly (n=29), with those who were subjected to undulatory physical resistance training. The participants were evaluated with several types of resistance training’s equipment before and after training protocol, by test of one maximal repetition. The subjects were trained on undulatory resistance three times per week for a period of 16 weeks. The overload used in undulatory resistance training was equivalent to 50% of one maximal repetition and 70% of one maximal repetition, alternating weekly. Statistical analysis revealed significant differences (p<0.05) between pre-test and post-test over a period of 16 weeks. Results The average gains in strength were 43.20% (knee extension), 65.00% (knee flexion), 27.80% (supine sitting machine), 31.00% (rowing sitting), 43.90% (biceps pulley), and 21.10% (triceps pulley). Conclusion Undulatory resistance training used with weekly different overloads was effective to provide significant gains in maximum strength in elderly type 2 diabetic individuals. PMID:25628192
Santos, Gilberto Monteiro dos; Montrezol, Fábio Tanil; Pauli, Luciana Santos Souza; Sartori-Cintra, Angélica Rossi; Colantonio, Emilson; Gomes, Ricardo José; Marinho, Rodolfo; Moura, Leandro Pereira de; Pauli, José Rodrigo
2014-01-01
To investigate the effects of a specific protocol of undulatory physical resistance training on maximal strength gains in elderly type 2 diabetics. The study included 48 subjects, aged between 60 and 85 years, of both genders. They were divided into two groups: Untrained Diabetic Elderly (n=19) with those who were not subjected to physical training and Trained Diabetic Elderly (n=29), with those who were subjected to undulatory physical resistance training. The participants were evaluated with several types of resistance training's equipment before and after training protocol, by test of one maximal repetition. The subjects were trained on undulatory resistance three times per week for a period of 16 weeks. The overload used in undulatory resistance training was equivalent to 50% of one maximal repetition and 70% of one maximal repetition, alternating weekly. Statistical analysis revealed significant differences (pUndulatory resistance training used with weekly different overloads was effective to provide significant gains in maximum strength in elderly type 2 diabetic individuals.
A New Augmentation Based Algorithm for Extracting Maximal Chordal Subgraphs.
Bhowmick, Sanjukta; Chen, Tzu-Yi; Halappanavar, Mahantesh
2015-02-01
A graph is chordal if every cycle of length greater than three contains an edge between non-adjacent vertices. Chordal graphs are of interest both theoretically, since they admit polynomial time solutions to a range of NP-hard graph problems, and practically, since they arise in many applications including sparse linear algebra, computer vision, and computational biology. A maximal chordal subgraph is a chordal subgraph that is not a proper subgraph of any other chordal subgraph. Existing algorithms for computing maximal chordal subgraphs depend on dynamically ordering the vertices, which is an inherently sequential process and therefore limits the algorithms' parallelizability. In this paper we explore techniques to develop a scalable parallel algorithm for extracting a maximal chordal subgraph. We demonstrate that an earlier attempt at developing a parallel algorithm may induce a non-optimal vertex ordering and is therefore not guaranteed to terminate with a maximal chordal subgraph. We then give a new algorithm that first computes and then repeatedly augments a spanning chordal subgraph. After proving that the algorithm terminates with a maximal chordal subgraph, we then demonstrate that this algorithm is more amenable to parallelization and that the parallel version also terminates with a maximal chordal subgraph. That said, the complexity of the new algorithm is higher than that of the previous parallel algorithm, although the earlier algorithm computes a chordal subgraph which is not guaranteed to be maximal. We experimented with our augmentation-based algorithm on both synthetic and real-world graphs. We provide scalability results and also explore the effect of different choices for the initial spanning chordal subgraph on both the running time and on the number of edges in the maximal chordal subgraph.
IMRank: Influence Maximization via Finding Self-Consistent Ranking
Cheng, Suqi; Shen, Hua-Wei; Huang, Junming; Chen, Wei; Cheng, Xue-Qi
2014-01-01
Influence maximization, fundamental for word-of-mouth marketing and viral marketing, aims to find a set of seed nodes maximizing influence spread on social network. Early methods mainly fall into two paradigms with certain benefits and drawbacks: (1)Greedy algorithms, selecting seed nodes one by one, give a guaranteed accuracy relying on the accurate approximation of influence spread with high computational cost; (2)Heuristic algorithms, estimating influence spread using efficient heuristics,...
Probing the deviation from maximal mixing of atmospheric neutrinos
Choubey, S; Choubey, Sandhya; Roy, Probir
2006-01-01
Pioneering atmospheric muon neutrino experiments have demonstrated the near-maximal magnitude of the flavor mixing angle $\\theta_{23}$. But the precise value of the deviation $D \\equiv 1/2 - \\sin^2 \\theta_{23}$ from maximality (if nonzero) needs to be known, being of great interest -- especially to builders of neutrino mass and mixing models. We quantitatively investigate in a three generation framework the feasibility of determining $D$ in a statistically significant manner from studies of the atmospheric $\
Shareholder, stakeholder-owner or broad stakeholder maximization
Mygind, Niels
2004-01-01
including the shareholders of a company. Although it may be the ultimate goal for Corporate Social Responsibility to achieve this kind of maximization, broad stakeholder maximization is quite difficult to give a precise definition. There is no one-dimensional measure to add different stakeholder benefits...... by other stakeholders' interests. These constraints vary for dif-ferent stakeholder owners and new standards for Corporate Social Responsibility and more active political consumers will strengthen these constraints....
Maximal speed of particles in super-Lévy process
LIN Zheng-yan; CHENG Zong-mao
2008-01-01
We introduce a super-Lévy process and study maximal speed of all particles process is a measure on the set of paths.We study the maximal speed of all particles during a given time period,which turns out to be a function of the packing dimension of the time period.We calculate the Hausdorff dimension of the set of a-fast patlls in the support and the range of the historical super-lévy process.
Chair Talk: Resources to Maximize Administrative Efforts
MacDonald, H.; Chan, M. A.; Bierly, E. W.; Manduca, C. A.; Ormand, C. J.
2009-12-01
Earth science department chairs are generally scientists who have little/no formal administrative training. The common rotation of faculty members in three-six year cycles distributes the heavy leadership responsibilities but involves little preparation beforehand to deal with budgets, fundraising, personnel issues, confrontations, and crises. The amount of information exchange and support upon exit and handoff to the next chair is variable. Resources for chairs include workshops, meetings (ranging from annual meetings of geoscience chairs to monthly meetings of small groups of chairs from various disciplines on a campus), discussions, and online resources. These resources, some of which we designed in the past several years, provide information and support for chairs, help them share best practices, and reduce time spent “reinventing the wheel”. Most of these resources involve groups of chairs in our discipline who meet together. The AGU Board of Heads and Chairs of Earth and Space Science Departments offers annual one-day workshops at the Fall AGU meeting. The specific topics vary from year to year; they have included goals and roles of heads and chairs, fundraising and Advisory Boards, student recruitment, interdisciplinarity, dual-career couples, and undergraduate research. The workshop provides ample opportunities for open discussion. Annual one-two day meetings of groups of geoscience department chairs (e.g., research universities in a particular region) provide an opportunity for chairs to share specific data about their departments (e.g., salaries, graduate student stipends, information about facilities) and discuss strategies. At the College of William and Mary, a small group of chairs meets monthly throughout the year; each session includes time for open discussion as well as a more structured discussion on a particular topic (e.g., merit review, development and fundraising, mentoring early career faculty and the tenure process, leadership styles
Hatem A. Emara
2015-10-01
Full Text Available Background: The most critical feature of motor development is the ability to balance the body in sitting or standing. Impaired balance limits a child’s ability to recover from unexpected threats to stability. The functional reach test (FRT defines the maximal distance an individual is able to reach forward beyond arm’s length in a standing position without loss of balance, taking a step, or touching the wall. The Purpose of this study was to establish the normal values for FRT in Saudi Arabia school children with typical development and to study the correlation of anthropometric measures with FRT values. Methods: This cross-sectional study was conducted in Almadinah Almonawarah, Kingdom of Saudi Arabia. A total of 280 children without disabilities aged 6 to 12 years were randomly selected. Functional reach was assessed by having subjects extend their arms to 90 degrees and reach as far forward as they could without taking a step. Reach distance was recorded by noting the beginning and final position of the subject's extended arm parallel to a yard stick attached to the wall. Three successive trials of FRT were performed and the mean of the three trials was calculated. Pearson product moment correlation was used to examine the association of FR to age, and anthropometric measures. Results: Normal mean values of FR ranged from 24.2cm to 33.95cm. Age, height and weight significantly correlate with FRT. Conclusion: The FRT is a feasible test to examine the balance of 6-12 year-old children. FRT may be useful for detecting balance impairment, change in balance performance over time.
Jay R. Hoffman
2007-03-01
Full Text Available Maximal strength and power testing are common assessments that are used to evaluate strength/power athletes. The validity and reliability of these tests have been well established (Hoffman, 2006, however the order of testing may have a profound effect on test performance outcome. It is generally recommended that the least fatiguing and highly-skilled tests are performed first, while highly fatiguing tests are performed last (Hoffman, 2006. Recent research has demonstrated that maximal isometric contractions and maximal or near- maximal dynamic exercise can augment the rate of force development, increase jump height and enhance sprint cycle performance (Chiu et al., 2003; French et al., 2003. The use of a maximal or near-maximal activity to enhance strength and power performance has been termed "muscle postactivation potentiation", and appears to be more common in the experienced resistance-trained athletes than in the recreationally-trained population (Chiu et al., 2003. It is believed that postactivation potentiation can enhance muscle performance by increasing the neural signal that activates the muscle (Hamada et al., 2000. Since heavy loading in a similar movement pattern of exercise appears to enhance maximal strength and power performance in the experienced resistance-trained athlete, it may be hypothesized that the postactivation potentiation associated with heavy loading has the potential to augment subsequent performance of tests utilizing similar motion. Therefore, consideration of an appropriate sequence of athletic performance testing in strength and power athletes is warranted. We would like to share our experience on the effect of performing a maximal lower body strength test on vertical jump performance in experienced resistance-trained strength/power athletes.We examined 64 NCAA Division III American collegiate football players (age = 20.1 ± 1.9 yr; body mass = 97.5 ± 17.8 kg; height = 1.80 ± 0.12 m. All testing was performed
Postural control during standing reach in children with Down syndrome.
Chen, Hao-Ling; Yeh, Chun-Fu; Howe, Tsu-Hsin
2015-03-01
The purpose of the present study was to investigate the dynamic postural control of children with Down syndrome (DS). Specifically, we compared postural control and goal-directed reaching performance between children with DS and typically developing children during standing reach. Standing reach performance was analyzed in three main phases using the kinematic and kinetic data collected from a force plate and a motion capture system. Fourteen children with DS, age and gender matched with fourteen typically developing children, were recruited for this study. The results showed that the demand of the standing reach task affected both dynamic postural control and reaching performance in children with DS, especially in the condition of beyond arm's length reaching. More postural adjustment strategies were recruited when reaching distance was beyond arm's length. Children with DS tended to use inefficient and conservative strategies for postural stability and reaching. That is, children with DS perform standing reach with increased reaction and execution time and decreased amplitudes of center of pressure displacements. Standing reach resembled functional balance that is required in daily activities. It is suggested to be considered as a part of strength and balance training program with graded task difficulty.
Evolution of Shanghai STOCK Market Based on Maximal Spanning Trees
Yang, Chunxia; Shen, Ying; Xia, Bingying
2013-01-01
In this paper, using a moving window to scan through every stock price time series over a period from 2 January 2001 to 11 March 2011 and mutual information to measure the statistical interdependence between stock prices, we construct a corresponding weighted network for 501 Shanghai stocks in every given window. Next, we extract its maximal spanning tree and understand the structure variation of Shanghai stock market by analyzing the average path length, the influence of the center node and the p-value for every maximal spanning tree. A further analysis of the structure properties of maximal spanning trees over different periods of Shanghai stock market is carried out. All the obtained results indicate that the periods around 8 August 2005, 17 October 2007 and 25 December 2008 are turning points of Shanghai stock market, at turning points, the topology structure of the maximal spanning tree changes obviously: the degree of separation between nodes increases; the structure becomes looser; the influence of the center node gets smaller, and the degree distribution of the maximal spanning tree is no longer a power-law distribution. Lastly, we give an analysis of the variations of the single-step and multi-step survival ratios for all maximal spanning trees and find that two stocks are closely bonded and hard to be broken in a short term, on the contrary, no pair of stocks remains closely bonded for a long time.
Maximizing ammonium nitrogen removal from solution using different zeolites.
Penn, Chad J; Warren, Jason G; Smith, Savannah
2010-01-01
Zeolite minerals are ideal for removing ammonium nitrogen (NH4(+)-N) from animal wastes, leachates, and industrial effluents. The objectives of this study were to compare NH4+ removal and kinetics among several commercially available zeolites under various conditions and determine if calorimetry could provide information regarding kinetics of NH4+ removal. Ammonium sorption onto potassium (K) saturated zeolites was compared using synthetic vs. natural swine effluent and with either traditional batch-shaken system or a "tea bag" approach in which zeolites were contained in a mesh sack and suspended in a solution of swine effluent. Ammonium sorption was measured at four retention times using a flow-through system, and the resulting heat response was measured using isothermal calorimetry. Ammonium removal was not significantly different in synthetic vs. natural swine effluent. Ammonium removal was lower in batch-stirred compared to batch-shaken systems, suggesting that diffusion between particles was rate-limiting in the former system. Flow-through cells possessing contact times > 100 s displayed greater NH4+ sorption than batch systems, suggesting that maintaining high NH4+ concentration in solution, removal of exchange products, and sufficient reaction time are critical to maximizing NH4+ removal by zeolites. Within 100 s after NH4+ addition, endothermic heat responses indicated that NH4(+)-K+ exchange had peaked; this was followed by significant heat rate reduction for 50 min. This confirmed findings of an initial fast NH4(+)-K+ exchange followed by a slower one and suggests the 100-s period of rapid reaction is an indicator of the minimum flow through retention time required to optimize NH4+ sorption to zeolites used in this study.
Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look.
Davydov, M; Krikorian, A D
2000-10-01
The adaptogen concept is examined from an historical, biological, chemical, pharmacological and medical perspective using a wide variety of primary and secondary literature. The definition of an adaptogen first proposed by Soviet scientists in the late 1950s, namely that an adaptogen is any substance that exerts effects on both sick and healthy individuals by 'correcting' any dysfunction(s) without producing unwanted side effects, was used as a point of departure. We attempted to identify critically what an adaptogen supposedly does and to determine whether the word embodies in and of itself any concept(s) acceptable to western conventional (allopathic) medicine. Special attention was paid to the reported pharmacological effects of the 'adaptogen-containing plant' Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae), referred to by some as 'Siberian ginseng', and to its secondary chemical composition. We conclude that so far as specific pharmacological activities are concerned there are a number of valid arguments for equating the action of so-called adaptogens with those of medicinal agents that have activities as anti-oxidants, and/or anti-cancerogenic, immunomodulatory and hypocholesteroletic as well as hypoglycemic and choleretic action. However, 'adaptogens' and 'anti-oxidants' etc. also show significant dissimilarities and these are discussed. Significantly, the classical definition of an adaptogen has much in common with views currently being invoked to describe and explain the 'placebo effect'. Nevertheless, the chemistry of the secondary compounds of Eleutherococcus isolated thus far and their pharmacological effects support our hypothesis that the reported beneficial effects of adaptogens derive from their capacity to exert protective and/or inhibitory action against free radicals. An inventory of the secondary substances contained in Eleutherococcus discloses a potential for a wide range of activities reported from work on cultured cell lines
Reaching the Students: A New Approach to Enhancing Science Literacy
McNamara, B. J.; Burnham, C. C.
2002-05-01
Most NSF supported programs directed at improving science literacy among university students who are not majoring in SMET normally target instruction in introductory science or math classes. Unfortunately these efforts seldom reach the vast majority of students at a university because students can fulfil their science requirement by taking several other classes or class sections that are not impacted by the NSF program. Ideally it would be desirable to address the issues of science literacy and science anxiety among non-science majors in a single class that is required of essentially all undergraduates. We describe such a program which is being tested at NMSU. The targeted class is the university's freshman level English class. The idea behind this effort is to provide students with the skills they will need to be successful in their science classes in a less threatening humanities environment. We describe the problems that this approach raises, suggest solutions to these problems, and then discuss the overall status of this effort.
Reach/frequency for printed media: Personal probabilities or models
Mortensen, Peter Stendahl
2000-01-01
that, in order to prevent bias, ratings per group must be used as reading probabilities. Nevertheless, in most cases, the estimates are still biased compared with panel data, thus overestimating net ´reach. Models with the same assumptions as with assignments of reading probabilities are presented......The author evaluates two different ways of estimating reach and frequency of plans for printed media. The first assigns reading probabilities to groups of respondents and calculates reach and frequency by simulation. the second estimates parameters to a model for reach/frequency. It is concluded...
Nueva política europea en productos químicos. REACH New European policy on chemical products. REACH
Francisco Vargas Marcos
2005-12-01
Regulation concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH. This proposal creates a European Chemicals Agency and establishes the REACH system with the following elements:Registration requires industry to obtain relevant information on their substances and to use data to manage them safely.Evaluation provides confidence that industry is meeting its obligations and prevents unnecessary testing.Authorisation of substances with properties of very high concern (CMRs, PBTs, endocrine disrupters for particular uses.Restriction as a safety net to manage risks that have not been addressed previously in the system.This system will provide information in several phases in order to know and reduce the risks derived from use of around 30,000 chemical substances that are manufactured/imported in the European Union in quantities over one ton per year. The information will be saved in a database after validation and may be used to establish a causal relationship between the environmental factors and the negative effects on health associated to the production and use of chemical products.
Lateral biases and fluctuations in infants' spontaneous arm movements and reaching.
Corbetta, D; Thelen, E
1999-05-01
The development of hand preference in infant reaching is marked by several lateral fluctuations. This study investigated whether similar lateral fluctuations were present in infants' spontaneous, nonreaching, and freely performed movements. We collected reaching and nonreaching movements kinematics in 4 infants that we followed longitudinally during their 1st year. In their 4th year, we assessed the direction of their hand preference. We found that lateral biases in spontaneous, nonreaching movements in the 1st year showed several shifts that were similar to those observed in reaching. Despite these shifts, all 4 infants traversed a short period of right-handedness. This right-handedness matched the direction of their hand preference at 3 years of age. We propose that shifts in the development of hand preference in the 1st year are linked to successive reorganizations of the motor system. These reorganizations take place as infants learn to sit, crawl, and walk.
Far-Reaching Impacts of African Dust- A Calipso Perspective
Yu, Hongbin; Chin, Mian; Yuan, Tianle; Bian, Huisheng; Prospero, Joseph; Omar, Ali; Remer, Lorraine; Winker, David; Yang, Yuekui; Zhang, Yan; Zhang, Zhibo
2014-01-01
African dust can transport across the tropical Atlantic and reach the Amazon basin, exerting far-reaching impacts on climate in downwind regions. The transported dust influences the surface-atmosphere interactions and cloud and precipitation processes through perturbing the surface radiative budget and atmospheric radiative heating and acting as cloud condensation nuclei and ice nuclei. Dust also influences biogeochemical cycle and climate through providing nutrients vital to the productivity of ocean biomass and Amazon forests. Assessing these climate impacts relies on an accurate quantification of dust transport and deposition. Currently model simulations show extremely large diversity, which calls for a need of observational constraints. Kaufman et al. (2005) estimated from MODIS aerosol measurements that about 144 Tg of dust is deposited into the tropical Atlantic and 50 Tg of dust into the Amazon in 2001. This estimated dust import to Amazon is a factor of 3-4 higher than other observations and models. However, several studies have argued that the oversimplified characterization of dust vertical profile in the study would have introduced large uncertainty and very likely a high bias. In this study we quantify the trans-Atlantic dust transport and deposition by using 7 years (2007-2013) observations from CALIPSO lidar. CALIPSO acquires high-resolution aerosol extinction and depolarization profiles in both cloud-free and above-cloud conditions. The unique CALIPSO capability of profiling aerosols above clouds offers an unprecedented opportunity of examining uncertainties associated with the use of MODIS clear-sky data. Dust is separated from other types of aerosols using the depolarization measurements. We estimated that on the basis of 7-year average, 118142 Tg of dust is deposited into the tropical Atlantic and 3860 Tg of dust into the Amazon basin. Substantial interannual variations are observed during the period, with the maximum to minimum ratio of about 1
Should these potential CMR substances have been registered under REACH?
Wedebye, Eva Bay; Nikolov, Nikolai Georgiev; Dybdahl, Marianne;
2013-01-01
(Q)SAR models were applied to screen around 68,000 REACH pre-registered substances for CMR properties (carcinogenic, mutagenic or toxic to reproduction). Predictions from 14 relevant models were combined to reach overall calls for C, M and R. Combining predictions may reduce “noise” and increase...
Guaranteed performance in reaching mode of sliding mode controlled systems
G K Singh; K E Holé
2004-02-01
Conventionally, the parameters of a sliding mode controller (SMC) are selected so as to reduce the time spent in the reaching mode. Although, an upper bound on the time to reach (reaching time) the sliding surface is easily derived, performance guarantee in the state/error space needs more consideration. This paper addresses the design of constant plus proportional rate reaching law-based SMC for second-order nonlinear systems. It is shown that this controller imposes a bounding second-order error-dynamics, and thus guarantees robust performance during the reaching phase. The choice of the controller parameters based on the time to reach a desirable level of output tracking error (OTE), rather than on the reaching time is proposed. Using the Lyapunov theory, it is shown that parameter selections, based on the reaching time criterion, may need substantially larger time to achieve the OTE. Simulation results are presented for a nonlinear spring-massdamper system. It is seen that parameter selections based on the proposed OTE criterion, result in substantially quicker tracking, while using similar levels of control effort.
MEI Yu-Xue; CHEN Lin; CHEN Yi-Xin
2006-01-01
@@ In a process of remote state preparation, the universality of quantum channel is an essential ingredient. That is, one quantum channel should be feasible to remotely prepare any given qubit state. This problem appears in a process where one uses non-maximally entangled state as the passage. We present a scheme in which any given qubit |φ〉 = cosθ|0〉 + sinθeiψ|1〉 could be remotely prepared by using minimum classical bits and the previously shared non-maximally entangled state with a high fidelity, under the condition that the receiver holds the knowledge of θ. This condition is helpful to reduce the necessary amount of quantum channels, which is proven to be a low quantity to realize the universality. We also give several methods to investigate the trade-off between this amount and the achievable fidelity of the protocol.
Using the "Zone" to Help Reach Every Learner
Silver, Debbie
2011-01-01
Basically everything associated with maximizing student engagement, achievement, optimal learning environment, learning zone, and the like can be attributed to the work of Lev Vygotsky (1978). A Russian psychologist and social constructivist, Vygotsky (1896-1934) proposed a concept so fundamental to the theory of motivation that it undergirds…
Using the "Zone" to Help Reach Every Learner
Silver, Debbie
2011-01-01
Basically everything associated with maximizing student engagement, achievement, optimal learning environment, learning zone, and the like can be attributed to the work of Lev Vygotsky (1978). A Russian psychologist and social constructivist, Vygotsky (1896-1934) proposed a concept so fundamental to the theory of motivation that it undergirds…
The Automorphism Groups of a Family of Maximal Curves
Guralnick, Robert; Pries, Rachel
2011-01-01
The Hasse Weil bound restricts the number of points of a curve which are defined over a finite field; if the number of points meets this bound, the curve is called maximal. Giulietti and Korchmaros introduced a curve C_3 which is maximal over F_{q^6} and determined its automorphism group. Garcia, Guneri, and Stichtenoth generalized this construction to a family of curves C_n, indexed by an odd integer n greater than or equal to 3, such that C_n is maximal over F_{q^{2n}}. In this paper, we determine the automorphism group Aut(C_n) when n > 3; in contrast with the case n=3, it fixes the point at infinity on C_n. The proof requires a new structural result about automorphism groups of curves in characteristic p such that each Sylow p-subgroup has exactly one fixed point. MSC:11G20, 14H37.
Online Learning of Assignments that Maximize Submodular Functions
Golovin, Daniel; Streeter, Matthew
2009-01-01
Which ads should we display in sponsored search in order to maximize our revenue? How should we dynamically rank information sources to maximize value of information? These applications exhibit strong diminishing returns: Selection of redundant ads and information sources decreases their marginal utility. We show that these and other problems can be formalized as repeatedly selecting an assignment of items to positions to maximize a sequence of monotone submodular functions that arrive one by one. We present an efficient algorithm for this general problem and analyze it in the no-regret model. Our algorithm possesses strong theoretical guarantees, such as a performance ratio that converges to the optimal constant of 1-1/e. We empirically evaluate our algorithm on two real-world online optimization problems on the web: ad allocation with submodular utilities, and dynamically ranking blogs to detect information cascades.
Optimal bounded control for maximizing reliability of Duhem hysteretic systems
Ming XU; Xiaoling JIN; Yong WANG; Zhilong HUANG
2015-01-01
The optimal bounded control of stochastic-excited systems with Duhem hysteretic components for maximizing system reliability is investigated. The Duhem hysteretic force is transformed to energy-depending damping and stiffness by the energy dissipation balance technique. The controlled system is transformed to the equivalent non-hysteretic system. Stochastic averaging is then implemented to obtain the Itˆo stochastic equation associated with the total energy of the vibrating system, appropriate for eval-uating system responses. Dynamical programming equations for maximizing system re-liability are formulated by the dynamical programming principle. The optimal bounded control is derived from the maximization condition in the dynamical programming equa-tion. Finally, the conditional reliability function and mean time of first-passage failure of the optimal Duhem systems are numerically solved from the Kolmogorov equations. The proposed procedure is illustrated with a representative example.
Eccentric exercise decreases maximal insulin action in humans
Asp, Svend; Daugaard, J R; Kristiansen, S
1996-01-01
1. Unaccustomed eccentric exercise decreases whole-body insulin action in humans. To study the effects of one-legged eccentric exercise on insulin action in muscle and systemically, the euglycaemic clamp technique combined with arterial and bilateral femoral venous catheterization was used. Seven...... subjects participated in two euglycaemic clamps, performed in random order. One clamp was preceded 2 days earlier by one-legged eccentric exercise (post-eccentric exercise clamp (PEC)) and one was without the prior exercise (control clamp (CC)). 2. During PEC the maximal insulin-stimulated glucose uptake......) necessary to maintain euglycaemia during maximal insulin stimulation was lower during PEC compared with CC (15.7%, 81.3 +/- 3.2 vs. 96.4 +/- 8.8 mumol kg-1 min-1, P eccentric exercise, muscle and whole-body insulin action is impaired at maximal...
Cross-Order Integral Relations from Maximal Cuts
Johansson, Henrik; Larsen, Kasper J.; Søgaard, Mads
2015-01-01
We study the ABDK relation using maximal cuts of one- and two-loop integrals with up to five external legs. We show how to find a special combination of integrals that allows the relation to exist, and how to reconstruct the terms with one-loop integrals squared. The reconstruction relies on the observation that integrals across different loop orders can have support on the same generalized unitarity cuts and can share global poles. We discuss the appearance of nonhomologous integration contours in multivariate residues. Their origin can be understood in simple terms, and their existence enables us to distinguish contributions from different integrals. Our analysis suggests that maximal and near-maximal cuts can be used to infer the existence of integral identities more generally.
Cycle length maximization in PWRs using empirical core models
Okafor, K.C.; Aldemir, T.
1987-01-01
The problem of maximizing cycle length in nuclear reactors through optimal fuel and poison management has been addressed by many investigators. An often-used neutronic modeling technique is to find correlations between the state and control variables to describe the response of the core to changes in the control variables. In this study, a set of linear correlations, generated by two-dimensional diffusion-depletion calculations, is used to find the enrichment distribution that maximizes cycle length for the initial core of a pressurized water reactor (PWR). These correlations (a) incorporate the effect of composition changes in all the control zones on a given fuel assembly and (b) are valid for a given range of control variables. The advantage of using such correlations is that the cycle length maximization problem can be reduced to a linear programming problem.
The F-Theorem and F-Maximization
Pufu, Silviu S
2016-01-01
This contribution contains a review of the role of the three-sphere free energy F in recent developments related to the F-theorem and F-maximization. The F-theorem states that for any Lorentz-invariant RG trajectory connecting a conformal field theory CFT_UV in the ultraviolet to a conformal field theory CFT_IR, the F-coefficient decreases: F_UV > F_IR. I provide many examples of CFTs where one can compute F, approximately or exactly, and discuss various checks of the F-theorem. F-maximization is the principle that in an N=2 SCFT, viewed as the deep IR limit of an RG trajectory preserving N=2 supersymmetry, the superconformal R-symmetry maximizes F within the set of all R-symmetries preserved by the RG trajectory. I review the derivation of this result and provide examples.
Viscosity and density dependence during maximal flow in man.
Staats, B A; Wilson, T A; Lai-Fook, S J; Rodarte, J R; Hyatt, R E
1980-02-01
Maximal expiratory flow curves were obtained from ten healthy subjects white breathing air and three other gas mixtures with different densities and viscosities. From these data, the magnitudes of the dependence of maximal flow on gas density and viscosity were obtained. The scaling laws of fluid mechanics, together with a model for the flow-limiting mechanism, were used to obtain a prediction of the relationship between the density dependence and the viscosity dependence of maximal flow. Although the data for individual subjects were too variable to allow a precise comparison with this prediction, the relationship between the mean density dependence and the mean viscosity dependence of all usbjects agreed with the theoretic prediction. This agreement supports the assumption, which is frequently made, that flow resistance rather than tissue visoelasticity is the dominant contributor to peripheral resistance. Information on the relationships between the pressure drop to the flow-limiting segment and flow, gas density and viscosity, and lung volume were also obtained.
Maximal supports and Schur-positivity among connected skew shapes
McNamara, Peter R W
2011-01-01
The Schur-positivity order on skew shapes is defined by B \\leq A if the difference s_A - s_B is Schur-positive. It is an open problem to determine those connected skew shapes that are maximal with respect to this ordering. A strong sufficient condition for the Schur-positivity of s_A - s_B is that the support of B is contained in that of A, where the support of B is defined to be the set of partitions lambda for which s_lambda appears in the Schur expansion of s_B. We show that to determine the maximal connected skew shapes in the Schur-positivity order and this support containment order, it suffices to consider a special class of ribbon shapes. We explicitly determine the support for these ribbon shapes, thereby determining the maximal connected skew shapes in the support containment order.
Cardiovascular consequences of bed rest: effect on maximal oxygen uptake
Convertino, V. A.
1997-01-01
Maximal oxygen uptake (VO2max) is reduced in healthy individuals confined to bed rest, suggesting it is independent of any disease state. The magnitude of reduction in VO2max is dependent on duration of bed rest and the initial level of aerobic fitness (VO2max), but it appears to be independent of age or gender. Bed rest induces an elevated maximal heart rate which, in turn, is associated with decreased cardiac vagal tone, increased sympathetic catecholamine secretion, and greater cardiac beta-receptor sensitivity. Despite the elevation in heart rate, VO2max is reduced primarily from decreased maximal stroke volume and cardiac output. An elevated ejection fraction during exercise following bed rest suggests that the lower stroke volume is not caused by ventricular dysfunction but is primarily the result of decreased venous return associated with lower circulating blood volume, reduced central venous pressure, and higher venous compliance in the lower extremities. VO2max, stroke volume, and cardiac output are further compromised by exercise in the upright posture. The contribution of hypovolemia to reduced cardiac output during exercise following bed rest is supported by the close relationship between the relative magnitude (% delta) and time course of change in blood volume and VO2max during bed rest, and also by the fact that retention of plasma volume is associated with maintenance of VO2max after bed rest. Arteriovenous oxygen difference during maximal exercise is not altered by bed rest, suggesting that peripheral mechanisms may not contribute significantly to the decreased VO2max. However reduction in baseline and maximal muscle blood flow, red blood cell volume, and capillarization in working muscles represent peripheral mechanisms that may contribute to limited oxygen delivery and, subsequently, lowered VO2max. Thus, alterations in cardiac and vascular functions induced by prolonged confinement to bed rest contribute to diminution of maximal oxygen uptake
Munch, G D W; Svendsen, J H; Damsgaard, R; Secher, N H; González-Alonso, J; Mortensen, S P
2014-01-15
In humans, maximal aerobic power (VO2 max ) is associated with a plateau in cardiac output (Q), but the mechanisms regulating the interplay between maximal heart rate (HRmax) and stroke volume (SV) are unclear. To evaluate the effect of tachycardia and elevations in HRmax on cardiovascular function and capacity during maximal exercise in healthy humans, 12 young male cyclists performed incremental cycling and one-legged knee-extensor exercise (KEE) to exhaustion with and without right atrial pacing to increase HR. During control cycling, Q and leg blood flow increased up to 85% of maximal workload (WLmax) and remained unchanged until exhaustion. SV initially increased, plateaued and then decreased before exhaustion (P rate pressure product and RAP (P heart can be paced to a higher HR than observed during maximal exercise, suggesting that HRmax and myocardial work capacity do not limit VO2 max in healthy individuals. A limited left ventricular filling and possibly altered contractility reduce SV during atrial pacing, whereas a plateau in LVFP appears to restrict Q close to VO2 max .
Kakeya sets and directional maximal operators in the plane
Bateman, Michael
2009-01-01
We completely characterize the boundedness of planar directional maximal operators on $L^p$ . More precisely, if $\\Omega$ is a set of directions, we show that $M_{\\Omega}$ , the maximal operator associated to line segments in the directions $\\Omega$ , is unbounded on $L^p$ for all $p \\lt \\infty$ precisely when $\\Omega$ admits Kakeya-type sets. In fact, we show that if $\\Omega$ does not admit Kakeya sets, then $\\Omega$ is a generalized lacunary set, and hence, $M_{\\Omega}$ is bounded on $L^p$ ...
Maximal slicings in spherical symmetry: local existence and construction
Cordero-Carrión, Isabel; Morales-Lladosa, Juan Antonio; 10.1063/1.3658864
2011-01-01
We show that any spherically symmetric spacetime locally admits a maximal spacelike slicing and we give a procedure allowing its construction. The construction procedure that we have designed is based on purely geometrical arguments and, in practice, leads to solve a decoupled system of first order quasi-linear partial differential equations. We have explicitly built up maximal foliations in Minkowski and Friedmann spacetimes. Our approach admits further generalizations and efficient computational implementation. As by product, we suggest some applications of our work in the task of calibrating Numerical Relativity complex codes, usually written in Cartesian coordinates.
How High Might the Revenue-maximizing Tax Rate Be?
Usher, Dan
2014-01-01
Through tax evasion, through the labour-leisure choice or in other ways, taxpayers reduce the tax base in response to an increase in the tax rate. The process is commonly-believed to generate a humped Laffer curve with a revenue-maximizing tax rate well short of 100%. That need not be so. In the â€œnew tax responsiveness literatureâ€ , the revenue-maximizing tax rate is inferred from the observed â€œelasticity of taxable incomeâ€ . It is shown in this article 1) that the inference is unwarran...
Maximizing opto‐mechanical interaction using topology optimization
Gersborg, Allan Roulund; Sigmund, Ole
2011-01-01
This paper studies topology optimization of a coupled opto‐mechanical problem with the goal of finding the material layout which maximizes the optical modulation, i.e. the difference between the optical response for the mechanically deformed and undeformed configuration. The optimization is perfo......This paper studies topology optimization of a coupled opto‐mechanical problem with the goal of finding the material layout which maximizes the optical modulation, i.e. the difference between the optical response for the mechanically deformed and undeformed configuration. The optimization...
Constraining Torsion in Maximally symmetric (sub)spaces
Sur, Sourav
2013-01-01
We look into the general aspects of space-time symmetries in presence of torsion, and how the latter is affected by such symmetries. Focusing in particular to space-times which either exhibit maximal symmetry on their own, or could be decomposed to maximally symmetric subspaces, we work out the constraints on torsion in two different theoretical schemes. We show that at least for a completely antisymmetric torsion tensor (for e.g. the one motivated from string theory), an equivalence is set between these two schemes, as the non-vanishing independent torsion tensor components turn out to be the same.
Gap processing for adaptive maximal Poisson-disk sampling
Yan, Dongming
2013-09-01
In this article, we study the generation of maximal Poisson-disk sets with varying radii. First, we present a geometric analysis of gaps in such disk sets. This analysis is the basis for maximal and adaptive sampling in Euclidean space and on manifolds. Second, we propose efficient algorithms and data structures to detect gaps and update gaps when disks are inserted, deleted, moved, or when their radii are changed.We build on the concepts of regular triangulations and the power diagram. Third, we show how our analysis contributes to the state-of-the-art in surface remeshing. © 2013 ACM.
Approximation algorithms for indefinite complex quadratic maximization problems
无
2010-01-01
In this paper,we consider the following indefinite complex quadratic maximization problem: maximize zHQz,subject to zk ∈ C and zkm = 1,k = 1,...,n,where Q is a Hermitian matrix with trQ = 0,z ∈ Cn is the decision vector,and m 3.An (1/log n) approximation algorithm is presented for such problem.Furthermore,we consider the above problem where the objective matrix Q is in bilinear form,in which case a 0.7118 cos mπ 2approximation algorithm can be constructed.In the context of quadratic optimization,various extensions and connections of the model are discussed.
Anatomy of maximal stop mixing in the MSSM
Bruemmer, Felix [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Kraml, Sabine; Kulkarni, Suchita [CNRS/IN2P3, INPG, Grenoble (France). Laboratoire de Physique Subatomique et de Cosmologie
2012-05-15
A Standard Model-like Higgs near 125 GeV in the MSSM requires multi-TeV stop masses, or a near-maximal contribution to its mass from stop mixing. We investigate the maximal mixing scenario, and in particular its prospects for being realized it in potentially realistic GUT models. We work out constraints on the possible GUT-scale soft terms, which we compare with what can be obtained from some well-known mechanisms of SUSY breaking mediation. Finally, we analyze two promising scenarios in detail, namely gaugino mediation and gravity mediation with non-universal Higgs masses.
Greedy SINR Maximization in Collaborative Multibase Wireless Systems
Popescu Otilia
2004-01-01
Full Text Available We present a codeword adaptation algorithm for collaborative multibase wireless systems. The system is modeled with multiple inputs and multiple outputs (MIMO in which information is transmitted using multicode CDMA, and codewords are adapted based on greedy maximization of the signal-to-interference-plus-noise ratio. The procedure monotonically increases the sum capacity and, when repeated iteratively for all codewords in the system, converges to a fixed point. Fixed-point properties and a connection with sum capacity maximization, along with a discussion of simulations that corroborate the basic analytic results, are included in the paper.
Weighted Inequalities for the Generalized Maximal Operator in Martingale Spaces
Wei CHEN; Peide LIU
2011-01-01
The generalized maximal operator M in martingale spaces is considered.For 1 ＜ p ≤ q ＜ ∞,the authors give a necessary and sufficient condition on the pair (（μ),v)for M to be a bounded operator from martingale space LP(v) into Lq(（μ）) or weak-Lq(（μ）),where （μ） is a measure on Ω× N and v a weight on Ω.Moreover,the similar inequalities for usual maximal operator are discussed.
Simulating Entangling Unitary Operator Using Non-maximally Entangled States
LI Chun-Xian; WANG Cheng-Zhi; NIE Liu-Ying; LI Jiang-Fan
2009-01-01
We use non-maximally entangled states (NMESs) to simulate an entangling unitary operator (EUO) w/th a certain probability. Given entanglement resources, the probability of the success we achieve is a decreasing function of the parameters of the EUO. Given an EUO, for certain entanglement resources the result is optimal, i.e., the probability obtains a maximal value, and for optimal result higher parameters of the EUO match more amount of entanglement resources. The probability of the success we achieve is higher than the known results under some condition.
Has the Brain Maximized its Information Storage Capacity?
Stepanyants, A L
2003-01-01
Learning and memory may rely on the ability of neuronal circuits to reorganize by dendritic spine remodeling. We have looked for geometrical parameters of cortical circuits, which maximize information storage capacity associated with this mechanism. In particular, we calculated optimal volume fractions of various neuropil components. The optimal axonal and dendritic volume fractions are not significantly different from anatomical measurements in the mouse and rat neocortex, and the rat hippocampus. This has led us to propose that the maximization of information storage capacity associated with dendritic spine remodeling may have been an important driving force in the evolution of the cortex.
Maximal expiratory flow volume curve in quarry workers.
Subhashini, Arcot Sadagopa; Satchidhanandam, Natesa
2002-01-01
Maximal Expiratory Flow Volume (MEFV) curves were recorded with a computerized Spirometer (Med Spiror). Forced Vital Capacity (FVC), Forced Expiratory Volumes (FEV), mean and maximal flow rates were obtained in 25 quarry workers who were free from respiratory disorders and 20 healthy control subjects. All the functional values are lower in quarry workers than in the control subject, the largest reduction in quarry workers with a work duration of over 15 years, especially for FEF75. The effects are probably due to smoking rather than dust exposure.
Efficient maximal Poisson-disk sampling and remeshing on surfaces
Guo, Jianwei
2015-02-01
Poisson-disk sampling is one of the fundamental research problems in computer graphics that has many applications. In this paper, we study the problem of maximal Poisson-disk sampling on mesh surfaces. We present a simple approach that generalizes the 2D maximal sampling framework to surfaces. The key observation is to use a subdivided mesh as the sampling domain for conflict checking and void detection. Our approach improves the state-of-the-art approach in efficiency, quality and the memory consumption.
Chiara eBegliomini
2014-09-01
Full Text Available Experimental evidence suggests the existence of a sophisticated brain circuit specifically dedicated to reach-to-grasp planning and execution, both in human and non human primates (Castiello, 2005. Studies accomplished by means of neuroimaging techniques suggest the hypothesis of a dichotomy between a reach-to-grasp circuit, involving the intraparietal area (AIP, the dorsal and ventral premotor cortices (PMd and PMv - Castiello and Begliomini, 2008; Filimon, 2010 and a reaching circuit involving the medial intraparietal area (mIP and the Superior Parieto-Occipital Cortex (SPOC (Culham et al., 2006. However, the time course characterizing the involvement of these regions during the planning and execution of these two types of movements has yet to be delineated. A functional magnetic resonance imaging (fMRI study has been conducted, including reach-to grasp and reaching only movements, performed towards either a small or a large stimulus, and Finite Impulse Response model (FIR - Henson, 2003 was adopted to monitor activation patterns from stimulus onset for a time window of 10 seconds duration. Data analysis focused on brain regions belonging either to the reaching or to the grasping network, as suggested by Castiello & Begliomini (2008.Results suggest that reaching and grasping movements planning and execution might share a common brain network, providing further confirmation to the idea that the neural underpinnings of reaching and grasping may overlap in both spatial and temporal terms (Verhagen et al., 2013.
Proprioceptive body illusions modulate the visual perception of reaching distance.
Agustin Petroni
Full Text Available The neurobiology of reaching has been extensively studied in human and non-human primates. However, the mechanisms that allow a subject to decide-without engaging in explicit action-whether an object is reachable are not fully understood. Some studies conclude that decisions near the reach limit depend on motor simulations of the reaching movement. Others have shown that the body schema plays a role in explicit and implicit distance estimation, especially after motor practice with a tool. In this study we evaluate the causal role of multisensory body representations in the perception of reachable space. We reasoned that if body schema is used to estimate reach, an illusion of the finger size induced by proprioceptive stimulation should propagate to the perception of reaching distances. To test this hypothesis we induced a proprioceptive illusion of extension or shrinkage of the right index finger while participants judged a series of LEDs as reachable or non-reachable without actual movement. Our results show that reach distance estimation depends on the illusory perceived size of the finger: illusory elongation produced a shift of reaching distance away from the body whereas illusory shrinkage produced the opposite effect. Combining these results with previous findings, we suggest that deciding if a target is reachable requires an integration of body inputs in high order multisensory parietal areas that engage in movement simulations through connections with frontal premotor areas.
The impact of REACH on classification for human health hazards.
Oltmanns, J; Bunke, D; Jenseit, W; Heidorn, C
2014-11-01
The REACH Regulation represents a major piece of chemical legislation in the EU and requires manufacturers and importers of chemicals to assess the safety of their substances. The classification of substances for their hazards is one of the crucial elements in this process. We analysed the effect of REACH on classification for human health endpoints by comparing information from REACH registration dossiers with legally binding, harmonised classifications. The analysis included 142 chemicals produced at very high tonnages in the EU, the majority of which have already been assessed in the past. Of 20 substances lacking a harmonised classification, 12 chemicals were classified in REACH registration dossiers. More importantly, 37 substances with harmonised classifications for human health endpoints had stricter classifications in registration dossiers and 29 of these were classified for at least one additional endpoint not covered by the harmonised classification. Substance-specific analyses suggest that one third of these additional endpoints emerged from experimental studies performed to fulfil information requirements under REACH, while two thirds resulted from a new assessment of pre-REACH studies. We conclude that REACH leads to an improved hazard characterisation even for substances with a potentially good data basis.
Proprioceptive Body Illusions Modulate the Visual Perception of Reaching Distance
Petroni, Agustin; Carbajal, M. Julia; Sigman, Mariano
2015-01-01
The neurobiology of reaching has been extensively studied in human and non-human primates. However, the mechanisms that allow a subject to decide—without engaging in explicit action—whether an object is reachable are not fully understood. Some studies conclude that decisions near the reach limit depend on motor simulations of the reaching movement. Others have shown that the body schema plays a role in explicit and implicit distance estimation, especially after motor practice with a tool. In this study we evaluate the causal role of multisensory body representations in the perception of reachable space. We reasoned that if body schema is used to estimate reach, an illusion of the finger size induced by proprioceptive stimulation should propagate to the perception of reaching distances. To test this hypothesis we induced a proprioceptive illusion of extension or shrinkage of the right index finger while participants judged a series of LEDs as reachable or non-reachable without actual movement. Our results show that reach distance estimation depends on the illusory perceived size of the finger: illusory elongation produced a shift of reaching distance away from the body whereas illusory shrinkage produced the opposite effect. Combining these results with previous findings, we suggest that deciding if a target is reachable requires an integration of body inputs in high order multisensory parietal areas that engage in movement simulations through connections with frontal premotor areas. PMID:26110274
2010-04-01
... Employment and Training Administration Maxim Integrated Products, Formerly Known as Dallas Semiconductor...). Information shows that Maxim Integrated Products was formerly known as Dallas Semiconductor. Some workers... insurance (UI) tax accounts under the names Maxim Integrated Products, Inc. and Dallas...
Advanced Reach Tool (ART): development of the mechanistic model.
Fransman, Wouter; Van Tongeren, Martie; Cherrie, John W; Tischer, Martin; Schneider, Thomas; Schinkel, Jody; Kromhout, Hans; Warren, Nick; Goede, Henk; Tielemans, Erik
2011-11-01
This paper describes the development of the mechanistic model within a collaborative project, referred to as the Advanced REACH Tool (ART) project, to develop a tool to model inhalation exposure for workers sharing similar operational conditions across different industries and locations in Europe. The ART mechanistic model is based on a conceptual framework that adopts a source receptor approach, which describes the transport of a contaminant from the source to the receptor and defines seven independent principal modifying factors: substance emission potential, activity emission potential, localized controls, segregation, personal enclosure, surface contamination, and dispersion. ART currently differentiates between three different exposure types: vapours, mists, and dust (fumes, fibres, and gases are presently excluded). Various sources were used to assign numerical values to the multipliers to each modifying factor. The evidence used to underpin this assessment procedure was based on chemical and physical laws. In addition, empirical data obtained from literature were used. Where this was not possible, expert elicitation was applied for the assessment procedure. Multipliers for all modifying factors were peer reviewed by leading experts from industry, research institutes, and public authorities across the globe. In addition, several workshops with experts were organized to discuss the proposed exposure multipliers. The mechanistic model is a central part of the ART tool and with advancing knowledge on exposure, determinants will require updates and refinements on a continuous basis, such as the effect of worker behaviour on personal exposure, 'best practice' values that describe the maximum achievable effectiveness of control measures, the intrinsic emission potential of various solid objects (e.g. metal, glass, plastics, etc.), and extending the applicability domain to certain types of exposures (e.g. gas, fume, and fibre exposure).
Yeh, C. H.; Chow, C. W.; Shih, F. Y.; Pan, C. L.
2012-08-01
The wavelength division multiplexing-time division multiplexing (WDM-TDM) passive optical network (PON) using reflective semiconductor optical amplifier (RSOA)-based colorless optical networking units (ONUs) is considered as a promising candidate for the realization of fiber-to-the-home (FTTH). And this architecture is actively considered by Industrial Technology Research Institute (ITRI) for the realization of FTTH in Taiwan. However, different fiber distances and optical components would introduce different power budgets to different ONUs in the PON. Besides, due to the aging of optical transmitter (Tx), the power decay of the distributed optical carrier from the central office (CO) could also reduce the injection power into each ONU. The situation will be more severe in the long-reach (LR) PON, which is considered as an option for the future access. In this work, we investigate a WDM-TDM PON using RSOA-based ONU for upstream data rate adjustment depending on different continuous wave (CW) injection powers. Both standard-reach (25 km) and LR (100 km) transmissions are evaluated. Moreover, a detail analysis of the upstream signal bit-error rate (BER) performances at different injection powers, upstream data rates, PON split-ratios under stand-reach and long-reach is presented.
50 years sets with positive reach - a survey -
Christoph Thäle
2008-09-01
Full Text Available The purpose of this paper is to summarize results on various aspects of sets with positive reach, which are up to now not available in such a compact form. After recalling briefly the results before 1959, sets with positive reach and their associated curvature measures are introduced. We develop an integral and current representation of these curvature measures and show how the current representation helps to prove integralgeometric formulas, such as the principal kinematic formula. Also random sets with positive reach and random mosaics (or the more general random cell-complexes with general cell shape are considered.
REACH Basics for Chinese Producers of Electric Household Appliances
Dr.Klaus W.Mehl
2008-01-01
The following article explains the EU chemical regulation "REACH', explicates the requirements that Chinese producers are facing, and shows how they can fulfill the requirements and secure their access to the EU market. The consequences of failing to fulfill REACH requirements are given in REACH Article 5: No data, no market: ... substances ... in articles ... shall not be ... placed on the market unless they have been registered In other words: Without registration of chemicals Chinese producers of electric household appliances may loose their EU market.
Biochemical changes in relation to a maximal exercise test in patients with fibromyalgia
Nørregaard, J; Bülow, P M; Mehlsen, J
1994-01-01
-1 was reached at a heart rate of 124 min-1 in the patients with fibromyalgia as compared to 140 min-1 in the controls (P = 0.02). In relation to workload, the patients scored higher on a Borg scale for perceived exertion during exercise, but if the Borg score was related to lactate no significant......Patients with fibromyalgia often complain of fatigue and pain during exercise and of worsening of pain days after exercise. The aim of the study described here was to determine if abnormal changes in potassium or lactate could be observed during an exercise test in fibromyalgia. Whether an abnormal...... incline in plasma creatine kinase or myoglobin could be observed days after the test was studied also. Fifteen female fibromyalgia patients and 15 age- and sex-matched controls performed a stepwise incremental maximal bicycle-ergometer test. Blood samples were collected from a catheter in a cubital vein...
An Expectation Maximization Algorithm to Model Failure Times by Continuous-Time Markov Chains
Qihong Duan
2010-01-01
Full Text Available In many applications, the failure rate function may present a bathtub shape curve. In this paper, an expectation maximization algorithm is proposed to construct a suitable continuous-time Markov chain which models the failure time data by the first time reaching the absorbing state. Assume that a system is described by methods of supplementary variables, the device of stage, and so on. Given a data set, the maximum likelihood estimators of the initial distribution and the infinitesimal transition rates of the Markov chain can be obtained by our novel algorithm. Suppose that there are m transient states in the system and that there are n failure time data. The devised algorithm only needs to compute the exponential of m×m upper triangular matrices for O(nm2 times in each iteration. Finally, the algorithm is applied to two real data sets, which indicates the practicality and efficiency of our algorithm.
Maximizing Science in the Era of LSST: A Community-Based Study of Needed US Capabilities
Najita, Joan; Finkbeiner, Douglas P; Foley, Ryan J; Hawley, Suzanne; Newman, Jeffrey A; Rudnick, Gregory; Simon, Joshua D; Trilling, David; Street, Rachel; Bolton, Adam; Angus, Ruth; Bell, Eric F; Buzasi, Derek; Ciardi, David; Davenport, James R A; Dawson, Will; Dickinson, Mark; Drlica-Wagner, Alex; Elias, Jay; Erb, Dawn; Feaga, Lori; Fong, Wen-fai; Gawiser, Eric; Giampapa, Mark; Guhathakurta, Puragra; Hoffman, Jennifer L; Hsieh, Henry; Jennings, Elise; Johnston, Kathryn V; Kashyap, Vinay; Li, Ting S; Linder, Eric; Mandelbaum, Rachel; Marshall, Phil; Matheson, Thomas; Meibom, Soren; Miller, Bryan W; O'Meara, John; Reddy, Vishnu; Ridgway, Steve; Rockosi, Constance M; Sand, David J; Schafer, Chad; Schmidt, Sam; Sesar, Branimir; Sheppard, Scott S; Thomas, Cristina A; Tollerud, Erik J; Trump, Jon; von der Linden, Anja
2016-01-01
The Large Synoptic Survey Telescope (LSST) will be a discovery machine for the astronomy and physics communities, revealing astrophysical phenomena from the Solar System to the outer reaches of the observable Universe. While many discoveries will be made using LSST data alone, taking full scientific advantage of LSST will require ground-based optical-infrared (OIR) supporting capabilities, e.g., observing time on telescopes, instrumentation, computing resources, and other infrastructure. This community-based study identifies, from a science-driven perspective, capabilities that are needed to maximize LSST science. Expanding on the initial steps taken in the 2015 OIR System Report, the study takes a detailed, quantitative look at the capabilities needed to accomplish six representative LSST-enabled science programs that connect closely with scientific priorities from the 2010 decadal surveys. The study prioritizes the resources needed to accomplish the science programs and highlights ways that existing, planne...
Baryogenesis, Dark Matter and the Maximal Temperature of the Early Universe
Buchmuller, Wilfried
2012-01-01
Mechanisms for the generation of the matter-antimatter asymmetry and dark matter strongly depend on the reheating temperature T_R, the maximal temperature reached in the early universe. Forthcoming results from the LHC, low energy experiments, astrophysical observations and the Planck satellite will significantly constrain baryogenesis and the nature of dark matter, and thereby provide valuable information about the very early hot universe. At present, a wide range of reheating temperatures is still consistent with observations. We illustrate possible origins of matter and dark matter with four examples: moduli decay, electroweak baryogenesis, leptogenesis in the nuMSM and thermal leptogenesis. Finally, we discuss the connection between baryogenesis, dark matter and inflation in the context of supersymmetric spontaneous B-L breaking.
Baryogenesis, dark matter and the maximal temperature of the early universe
Buchmueller, Wilfried
2012-12-15
Mechanisms for the generation of the matter-antimatter asymmetry and dark matter strongly depend on the reheating temperature T{sub R}, the maximal temperature reached in the early universe. Forthcoming results from the LHC, low energy experiments, astrophysical observations and the Planck satellite will significantly constrain baryogenesis and the nature of dark matter, and thereby provide valuable information about the very early hot universe. At present, a wide range of reheating temperatures is still consistent with observations. We illustrate possible origins of matter and dark matter with four examples: moduli decay, electroweak baryogenesis, leptogenesis in the {nu}MSM and thermal leptogenesis. Finally, we discuss the connection between baryogenesis, dark matter and inflation in the context of supersymmetric spontaneous B-L breaking.
Kordík J.
2016-01-01
Full Text Available The goal of this paper is to find an optimal nozzle size of an axisymmetric synthetic jet actuator based on a loudspeaker. The desirable maximized output quantities are: volumetric flow, momentum flux, and kinetic energy flux. To evaluate these quantities velocity profiles were measured using a hot-wire probe at the actuator nozzle exit. Six different nozzle diameters and three supplied real power levels were tested to find the maxima of the quantities. The actuator operated always at resonance during experiments. It was found out that the momentum flux and the kinetic energy flux reach distinguishable local maxima at particular diameters of the nozzle. Besides, the maxima of the particular quantities do not coincide and the best nozzle size slightly increases with the supplied real power to the actuator.
Komura Taku
2007-06-01
Full Text Available Abstract Background The purpose of this study was to investigate the coordination strategy of maximal-effort horizontal jumping in comparison with vertical jumping, using the methodology of computer simulation. Methods A skeletal model that has nine rigid body segments and twenty degrees of freedom was developed. Thirty-two Hill-type lower limb muscles were attached to the model. The excitation-contraction dynamics of the contractile element, the tissues around the joints to limit the joint range of motion, as well as the foot-ground interaction were implemented. Simulations were initiated from an identical standing posture for both motions. Optimal pattern of the activation input signal was searched through numerical optimization. For the horizontal jumping, the goal was to maximize the horizontal distance traveled by the body's center of mass. For the vertical jumping, the goal was to maximize the height reached by the body's center of mass. Results As a result, it was found that the hip joint was utilized more vigorously in the horizontal jumping than in the vertical jumping. The muscles that have a function of joint flexion such as the m. iliopsoas, m. rectus femoris and m. tibialis anterior were activated to a greater level during the countermovement in the horizontal jumping with an effect of moving the body's center of mass in the forward direction. Muscular work was transferred to the mechanical energy of the body's center of mass more effectively in the horizontal jump, which resulted in a greater energy gain of the body's center of mass throughout the motion. Conclusion These differences in the optimal coordination strategy seem to be caused from the requirement that the body's center of mass needs to be located above the feet in a vertical jumping, whereas this requirement is not so strict in a horizontal jumping.
McNeil, Chris J; Allen, Matti D; Olympico, Eric; Shoemaker, J Kevin; Rice, Charles L
2015-09-01
A reduction of blood flow to active muscle will precipitate fatigue, and sustained isometric contractions produce intramuscular and compartmental pressures that can limit flow. The present study explored how blood flow and muscle oxygenation respond to isometric contractions at low, moderate, and maximal intensities. Over two visits, 10 males (26 ± 2 yr; means ± SD) performed 1-min dorsiflexion contractions at 30, 60, and 100% of maximal voluntary contraction (MVC) torque. Doppler ultrasound of the anterior tibial artery was used to record arterial diameter and mean blood velocity and to calculate absolute blood flow. The tissue oxygenation index (TOI) of tibialis anterior was acquired with near-infrared spectroscopy (NIRS). There was a progressive increase in blood flow at 30% MVC (peak of 289 ± 139% resting value), no change from rest until an increase in the final 10 s of exercise at 60% MVC (peak of 197 ± 102% rest), and an initial decrease (59 ± 30% resting value) followed by a progressive increase at 100% MVC (peak of 355 ± 133% rest). Blood flow was greater at 30 and 100% than 60% MVC during the last 30 s of exercise. TOI was ∼63% at rest and, within 30 s of exercise, reached steady-state values of ∼42%, ∼22%, and ∼22% for 30, 60, and 100% MVC, respectively. Even maximal contraction of the dorsiflexors is unable to cause more than a transient decrease of flow in the anterior tibial artery. Unlike dynamic or intermittent isometric exercise, our results indicate blood flow is not linearly graded with intensity or directly coupled with oxygenation during sustained isometric contractions.
Reliability of the calculated maximal lactate steady state in amateur cyclists
Jennifer Adam
2015-01-01
Full Text Available Complex performance diagnostics in sports medicine should contain maximal aerobic and maximal anaerobic performance. The requirements on appropriate stress protocols are high. To validate a test protocol quality criteria like objectivity and reliability are necessary. Therefore, the present study was performed in intention to analyze the reliability of maximal lactate production rate ( VLamax by using a sprint test, maximum oxygen consumption ( VO 2max by using a ramp test and, based on these data, resulting power in calculated maximum lactate-steady-state (PMLSS especially for amateur cyclists. All subjects (n=23, age 26 ± 4 years were leisure cyclists. At three different days they completed first a sprint test to approximate VLamax. After 60 min of recreation time a ramp test to assess VO 2max was performed. The results of VLamax-test and VO 2max -test and the body weight were used to calculate PMLSS for all subjects. The intra class correlation (ICC for VLamax and VO 2max was 0.904 and 0.987, respectively, coefficient of variation (CV was 6.3 % and 2.1 %, respectively. Between the measurements the reliable change index of 0.11 mmol∙l-1∙s-1 for VLamax and 3.3 ml∙kg-1∙min-1 for VO 2max achieved significance. The mean of the calculated PMLSS was 237 ± 72 W with an RCI of 9 W and reached with ICC = 0.985 a very high reliability. Both metabolic performance tests and the calculated PMLSS are reliable for leisure cyclists.
K. Montague
2000-02-23
The purpose of this calculation is to develop additional Biosphere Dose Conversion Factors (BDCFs) for a reasonably maximally exposed individual (RMEI) for the periods 10,000 years and 1,000,000 years after the repository closure. In addition, Biosphere Dose Conversion Factors for the average member of a critical group are calculated for those additional radionuclides postulated to reach the environment during the period after 10,000 years and up to 1,000,000 years. After the permanent closure of the repository, the engineered systems within the repository will eventually lose their abilities to contain radionuclide inventory, and the radionuclides will migrate through the geosphere and eventually enter the local water table moving toward inhabited areas. The primary release scenario is a groundwater well used for drinking water supply and irrigation, and this calculation takes these postulated releases and follows them through various pathways until they result in a dose to either a member of critical group or a reasonably maximally exposed individual. The pathways considered in this calculation include inhalation, ingestion, and direct exposure.
Research on the evolution of stock correlation based on maximal spanning trees
Yang, Chunxia; Zhu, Xueshuai; Li, Qian; Chen, Yanhua; Deng, Qiangqiang
2014-12-01
In this study, we choose the daily closing price of 268 constituent stocks of the S&P 500 index, 221 stocks of London Stock Exchange, 148 constituent stocks of the Shanghai Composite index and 152 constituent stocks of the Hang Seng index as the research objects and select the sample of all the stock markets from 2 January, 2003, to 16 September, 2013. For each stock market, first, using a moving window to scan through every stock return series and mutual information to measure the statistical interdependence between stock returns, we construct a corresponding weighted network in every given window. Then we study the evolution of stock correlation by analyzing the average mutual information, mutual information distribution and topology structure’s variation of the maximal spanning tree extracting from every weighted network. All the obtained results indicate that for all the stock markets, both the average mutual information and the standard deviation of mutual information distribution first gradually increase and they reach a peak during the full-outbreak periods, and finally, they decrease again. In addition, the topology structure of the maximal spanning tree also changes from compact star-like to loose chain-like first and then turns to compact star-like once more. All the facts tell us that the crisis does change the stock correlation and the stock correlation is from weak to strong first, and then becomes weak again.
2012-01-01
Background Synchronized bursting activity (SBA) is a remarkable dynamical behavior in both ex vivo and in vivo neural networks. Investigations of the underlying structural characteristics associated with SBA are crucial to understanding the system-level regulatory mechanism of neural network behaviors. Results In this study, artificial pulsed neural networks were established using spike response models to capture fundamental dynamics of large scale ex vivo cortical networks. Network simulations with synaptic parameter perturbations showed the following two findings. (i) In a network with an excitatory ratio (ER) of 80-90%, its connective ratio (CR) was within a range of 10-30% when the occurrence of SBA reached the highest expectation. This result was consistent with the experimental observation in ex vivo neuronal networks, which were reported to possess a matured inhibitory synaptic ratio of 10-20% and a CR of 10-30%. (ii) No SBA occurred when a network does not contain any all-positive-interaction feedback loop (APFL) motif. In a neural network containing APFLs, the number of APFLs presented an optimal range corresponding to the maximal occurrence of SBA, which was very similar to the optimal CR. Conclusions In a neural network, the evolutionarily selected CR (10-30%) optimizes the occurrence of SBA, and APFL serves a pivotal network motif required to maximize the occurrence of SBA. PMID:22462685
Maximization of learning speed in the motor cortex due to neuronal redundancy.
Ken Takiyama
2012-01-01
Full Text Available Many redundancies play functional roles in motor control and motor learning. For example, kinematic and muscle redundancies contribute to stabilizing posture and impedance control, respectively. Another redundancy is the number of neurons themselves; there are overwhelmingly more neurons than muscles, and many combinations of neural activation can generate identical muscle activity. The functional roles of this neuronal redundancy remains unknown. Analysis of a redundant neural network model makes it possible to investigate these functional roles while varying the number of model neurons and holding constant the number of output units. Our analysis reveals that learning speed reaches its maximum value if and only if the model includes sufficient neuronal redundancy. This analytical result does not depend on whether the distribution of the preferred direction is uniform or a skewed bimodal, both of which have been reported in neurophysiological studies. Neuronal redundancy maximizes learning speed, even if the neural network model includes recurrent connections, a nonlinear activation function, or nonlinear muscle units. Furthermore, our results do not rely on the shape of the generalization function. The results of this study suggest that one of the functional roles of neuronal redundancy is to maximize learning speed.
Dong Chao-Yi
2012-03-01
Full Text Available Abstract Background Synchronized bursting activity (SBA is a remarkable dynamical behavior in both ex vivo and in vivo neural networks. Investigations of the underlying structural characteristics associated with SBA are crucial to understanding the system-level regulatory mechanism of neural network behaviors. Results In this study, artificial pulsed neural networks were established using spike response models to capture fundamental dynamics of large scale ex vivo cortical networks. Network simulations with synaptic parameter perturbations showed the following two findings. (i In a network with an excitatory ratio (ER of 80-90%, its connective ratio (CR was within a range of 10-30% when the occurrence of SBA reached the highest expectation. This result was consistent with the experimental observation in ex vivo neuronal networks, which were reported to possess a matured inhibitory synaptic ratio of 10-20% and a CR of 10-30%. (ii No SBA occurred when a network does not contain any all-positive-interaction feedback loop (APFL motif. In a neural network containing APFLs, the number of APFLs presented an optimal range corresponding to the maximal occurrence of SBA, which was very similar to the optimal CR. Conclusions In a neural network, the evolutionarily selected CR (10-30% optimizes the occurrence of SBA, and APFL serves a pivotal network motif required to maximize the occurrence of SBA.
Twitch interpolation technique in testing of maximal muscle strength
Bülow, P M; Nørregaard, J; Danneskiold-Samsøe, B
1993-01-01
The aim was to study the methodological aspects of the muscle twitch interpolation technique in estimating the maximal force of contraction in the quadriceps muscle utilizing commercial muscle testing equipment. Six healthy subjects participated in seven sets of experiments testing the effects on...
Octonionization of three player, two strategy maximally entangled quantum games
Ahmed, Aden; Bleiler, Steve; Khan, Faisal Shah
2008-01-01
We develop an octonionic representation of the payoff function for three player, two strategy, maximally entangled quantum games in order to obtain computationally friendly version of this function. This computational capability is then exploited to analyze and potentially classify the Nash equilibria in the quantum games.
Applications of expectation maximization algorithm for coherent optical communication
Carvalho, L.; Oliveira, J.; Zibar, Darko
2014-01-01
In this invited paper, we present powerful statistical signal processing methods, used by machine learning community, and link them to current problems in optical communication. In particular, we will look into iterative maximum likelihood parameter estimation based on expectation maximization al...
Joint Iterative Carrier Synchronization and Signal Detection Employing Expectation Maximization
Zibar, Darko; de Carvalho, Luis Henrique Hecker; Estaran Tolosa, Jose Manuel
2014-01-01
In this paper, joint estimation of carrier frequency, phase, signal means and noise variance, in a maximum likelihood sense, is performed iteratively by employing expectation maximization. The parameter estimation is soft decision driven and allows joint carrier synchronization and data detection...
Quantitative approaches for profit maximization in direct marketing
van der Scheer, H.R.
1998-01-01
An effective direct marketing campaign aims at selecting those targets, offer and communication elements - at the right time - that maximize the net profits. The list of individuals to be mailed, i.e. the targets, is considered to be the most important component. Therefore, a large amount of direct
The Boundary Crossing Theorem and the Maximal Stability Interval
Jorge-Antonio López-Renteria
2011-01-01
useful tools in the study of the stability of family of polynomials. Although both of these theorem seem intuitively obvious, they can be used for proving important results. In this paper, we give generalizations of these two theorems and we apply such generalizations for finding the maximal stability interval.
Optimal technique for maximal forward rotating vaults in men's gymnastics.
Hiley, Michael J; Jackson, Monique I; Yeadon, Maurice R
2015-08-01
In vaulting a gymnast must generate sufficient linear and angular momentum during the approach and table contact to complete the rotational requirements in the post-flight phase. This study investigated the optimization of table touchdown conditions and table contact technique for the maximization of rotation potential for forwards rotating vaults. A planar seven-segment torque-driven computer simulation model of the contact phase in vaulting was evaluated by varying joint torque activation time histories to match three performances of a handspring double somersault vault by an elite gymnast. The closest matching simulation was used as a starting point to maximize post-flight rotation potential (the product of angular momentum and flight time) for a forwards rotating vault. It was found that the maximized rotation potential was sufficient to produce a handspring double piked somersault vault. The corresponding optimal touchdown configuration exhibited hip flexion in contrast to the hyperextended configuration required for maximal height. Increasing touchdown velocity and angular momentum lead to additional post-flight rotation potential. By increasing the horizontal velocity at table touchdown, within limits obtained from recorded performances, the handspring double somersault tucked with one and a half twists, and the handspring triple somersault tucked became theoretically possible. Copyright © 2015 Elsevier B.V. All rights reserved.
Two-Loop Maximal Unitarity with External Masses
Johansson, Henrik; Larsen, Kasper J
2013-01-01
We extend the maximal unitarity method at two loops to double-box basis integrals with up to three external massive legs. We use consistency equations based on the requirement that integrals of total derivatives vanish. We obtain unique formulae for the coefficients of the master double-box integrals. These formulae can be used either analytically or numerically.
The influence of body position on maximal performance in cycling.
Welbergen, E; Clijsen, L P
1990-01-01
Six healthy male subjects performed a 3-min supramaximal test in four different cycling positions: two with different trunk angles and two with different saddle-tube angles. Maximal power output and maximal oxygen uptake (VO2max) were measured. Maximal power output was significantly higher in a standard sitting (SS, 381 W, SD 49) upright position compared to all other positions: standard racing (SR, 364 W, SD 49), recumbent backwards (RB, 355 W, SD 44) and recumbent forwards (RF, 341 W, SD 54). Although VO2max was also highest in SS (4.31 l.min-1, SD 0.5) upright position, the differences in VO2max were not significant (SR, 4.2 l.min-1, SD 0.53; RB, 4.17 l.min-1, SD 0.58; RF, 4.11 l.min-1, SD 0.66). It is concluded that (supra)maximal tests on a cycle ergometer should be performed in a sitting upright position and not in a racing position. In some cases when cycling on the road, higher speeds can be attained when sitting upright. This is especially true when cycling uphill when high power must be generated to overcome gravity but the road speed, and hence the power required to overcome air resistance, is relatively low.
A Revenue Maximization Approach for Provisioning Services in Clouds
Li Pan
2015-01-01
Full Text Available With the increased reliability, security, and reduced cost of cloud services, more and more users are attracted to having their jobs and applications outsourced into IAAS data centers. For a cloud provider, deciding how to provision services to clients is far from trivial. The objective of this decision is maximizing the provider’s revenue, while fulfilling its IAAS resource constraints. The above problem is defined as IAAS cloud provider revenue maximization (ICPRM problem in this paper. We formulate a service provision approach to help a cloud provider to determine which combination of clients to admit and in what Quality-of-Service (QoS levels and to maximize provider’s revenue given its available resources. We show that the overall problem is a nondeterministic polynomial- (NP- hard one and develop metaheuristic solutions based on the genetic algorithm to achieve revenue maximization. The experimental simulations and numerical results show that the proposed approach is both effective and efficient in solving ICPRM problems.
Teacher Praise: Maximizing the Motivational Impact. Teaching Strategies.
McVey, Mary D.
2001-01-01
Recognizes the influence of praise on human behavior, and provides specific suggestions on how to maximize the positive effects of praise when intended as positive reinforcement. Examines contingency, specificity, and selectivity aspects of praise. Cautions teachers to avoid the controlling effects of praise and the possibility that praise may…
Maximizing Access, Equity, and Inclusion in General and Special Education
Obiakor, Festus E.
2011-01-01
The goal of any educational program is to help its students to maximize their fullest potential in inclusive environments. For many students with disabilities, having an inclusive environment seems to be an ideal policy. Ironically, this policy continues to be debatable and controversial. Sometimes, the controversy or debate dominates the real…
Curriculum and Testing Strategies to Maximize Special Education STAAR Achievement
Johnson, William L.; Johnson, Annabel M.; Johnson, Jared W.
2015-01-01
This document is from a presentation at the 2015 annual conference of the Science Teachers Association of Texas (STAT). The two sessions (each listed as feature sessions at the state conference) examined classroom strategies the presenter used in his chemistry classes to maximize Texas end-of-course chemistry test scores for his special population…
Simplicity and maximal commutative subalgebras of twisted generalized Weyl algebras
Hartwig, J.T.; Öinert, Per Johan
2013-01-01
conditions for certain TGWAs to be simple, in the case when R is commutative. We illustrate our theorems by considering some special classes of TGWAs and providing concrete examples. We also discuss how simplicity of a TGWA is related to the maximal commutativity of R and the (non-)existence of non...
Lifetime maximization routing with network coding in wireless multihop networks
DING LiangHui; WU Ping; WANG Hao; PAN ZhiWen; YOU XiaoHu
2013-01-01
In this paper, we consider the lifetime maximization routing with network coding in wireless mul- tihop networks. We first show that lifetime maximization with network coding is different from pure routing, throughput maximization with network coding and energy minimization with network coding. Then we formulate lifetime maximization problems in three different cases of （i） no network coding, （ii） two-way network coding, and （iii） overhearing network coding. To solve these problems, we use flow augmenting routing （FA） for the first case, and then extend the FA with network coding （FANC） by using energy minimized one-hop network coding. After that, we investigate the influence of parameters of FANC, evaluate the performance of FANC with two-way and overhearing network coding schemes and compare it with that without network coding under two different power control models, namely, protocol and physical ones. The results show that the lifetime can be improved significantly by using network coding, and the performance gain of network coding decreases with the increase of flow asymmetry and the power control ability.
The Long Conversation Maximizing Business Value from Information Technology Investment
Lorenzo, Oswaldo; González, Gastón; Ramdani, Boumediene
2011-01-01
For many years companies have been investing in enterprise systems and IT initiatives but they are now struggling to achieve the desired results. It takes a long time to make the best of your enterprise systems so businesses must stop looking for the next technology 'silver bullet' and instead maximize the value of existing IT investments.
5D Maximally Supersymmetric Yang-Mills on the Lattice
Joseph, Anosh
2016-01-01
We provide details of the lattice construction of five-dimensional maximally supersymmetric Yang-Mills theory. The lattice theory is supersymmetric, gauge invariant and free from spectrum doublers. Such a supersymmetric lattice formulation is interesting as it can be used for non-perturbative explorations of the five-dimensional theory, which has a known gravitational dual.
Entropy Maximization and the Spatial Distribution of Species
Haegeman, Bart; Etienne, Rampal S.
2010-01-01
Entropy maximization (EM, also known as MaxEnt) is a general inference procedure that originated in statistical mechanics. It has been applied recently to predict ecological patterns, such as species abundance distributions and species-area relationships. It is well known in physics that the EM resu
AN EXISTENCE THEOREM FOR MAXIMAL ELEMENTS AND ITS APPLICATIONS
Hou Jicheng; He Wei
2007-01-01
An existence theorem of maximal elements for an L*-majorized correspondence de-fined on a non-paracompact H-space is established. As applications of the result, an equilibrium existence theorem for a non-paracompact generalized game in H-spaces with infinitely many players and with L*-majorized correspondences is given.
Successive superalgebraic truncations from the four-dimensional maximal supergravity
Kim, C H; Kim, K Y; Kim, Y; Kim, Chang Ho; Park, Young Jai; Kim, Kee Yong; Kim, Yongduk
1994-01-01
We study the four-dimensional {\\it N}=8 maximal supergravity in the context of Lie superalgebra SU(8/1). All possible successive superalgebraic truncations from four-dimensional {\\it N}=8 theory to {\\it N}=7, 6, \\cdots, 1 supergravity theories are systematically realized as sub-superalgebra chains of SU(8/1) by using the Kac-Dynkin weight techniques.
Maximal Regularity of the Discrete Harmonic Oscillator Equation
Airton Castro
2009-01-01
Full Text Available We give a representation of the solution for the best approximation of the harmonic oscillator equation formulated in a general Banach space setting, and a characterization of lp-maximal regularity—or well posedness—solely in terms of R-boundedness properties of the resolvent operator involved in the equation.
Statistical mechanics of influence maximization with thermal noise
Lynn, Christopher W.; Lee, Daniel D.
2017-03-01
The problem of optimally distributing a budget of influence among individuals in a social network, known as influence maximization, has typically been studied in the context of contagion models and deterministic processes, which fail to capture stochastic interactions inherent in real-world settings. Here, we show that by introducing thermal noise into influence models, the dynamics exactly resemble spins in a heterogeneous Ising system. In this way, influence maximization in the presence of thermal noise has a natural physical interpretation as maximizing the magnetization of an Ising system given a budget of external magnetic field. Using this statistical mechanical formulation, we demonstrate analytically that for small external-field budgets, the optimal influence solutions exhibit a highly non-trivial temperature dependence, focusing on high-degree hub nodes at high temperatures and on easily influenced peripheral nodes at low temperatures. For the general problem, we present a projected gradient ascent algorithm that uses the magnetic susceptibility to calculate locally optimal external-field distributions. We apply our algorithm to synthetic and real-world networks, demonstrating that our analytic results generalize qualitatively. Our work establishes a fruitful connection with statistical mechanics and demonstrates that influence maximization depends crucially on the temperature of the system, a fact that has not been appreciated by existing research.
Determinants of maximally attained level of pulmonary function
Wang, XB; Mensinga, TT; Schouten, JP; Rijcken, B; Weiss, ST
2004-01-01
This study investigated the determinants of sex-specific maximally attained levels of FEV1, VC, and the ratio of FEV1 to VC. Subjects were between the ages of 15 and 35 years (1,818 males and 1,732 females), participating in the Vlagtwedde/Vlaardingen study in The Netherlands. The subjects were foll
Modifying Softball for Maximizing Learning Outcomes in Physical Education
Brian, Ali; Ward, Phillip; Goodway, Jacqueline D.; Sutherland, Sue
2014-01-01
Softball is taught in many physical education programs throughout the United States. This article describes modifications that maximize learning outcomes and that address the National Standards and safety recommendations. The modifications focus on tasks and equipment, developmentally appropriate motor-skill acquisition, increasing number of…
Should I Stay or Should I Go? Maximizers versus Satisficers
Buri, John R.; Gunty, Amy; King, Stephanie L.
2008-01-01
In the present study, university students were presented a scenario in which a married couple was struggling in their marriage. These students were asked how likely it is that they would stay in a difficult marriage like the one described in the scenario. Each student also completed Schwartz's (2004) Maximization Scale. High scorers on this scale…
Nursing Students' Awareness and Intentional Maximization of Their Learning Styles
Mayfield, Linda Riggs
2012-01-01
This small, descriptive, pilot study addressed survey data from four levels of nursing students who had been taught to maximize their learning styles in a first-semester freshman success skills course. Bandura's Agency Theory supports the design. The hypothesis was that without reinforcing instruction, the students' recall and application of that…
The Effects of Leniency on Maximal Cartel Pricing
Houba, H.E.D.; Motchenkova, E.; Wen, Q.
2009-01-01
We analyze maximal cartel prices in infnitely-repeated oligopoly models under leniency where fines are linked to illegal gains, as often outlined in existing antitrust regulation, and detection probabilities depend on the degree of collusion. We introduce cartel culture that describes how likely car
A Data-Based Approach to Social Influence Maximization
Goyal, Amit; Lakshmanan, Laks V S
2011-01-01
Influence maximization is the problem of finding a set of users in a social network, such that by targeting this set, one maximizes the expected spread of influence in the network. Most of the literature on this topic has focused exclusively on the social graph, overlooking historical data, i.e., traces of past action propagations. In this paper, we study influence maximization from a novel data-based perspective. In particular, we introduce a new model, which we call credit distribution, that directly leverages available propagation traces to learn how influence flows in the network and uses this to estimate expected influence spread. Our approach also learns the different levels of influenceability of users, and it is time-aware in the sense that it takes the temporal nature of influence into account. We show that influence maximization under the credit distribution model is NP-hard and that the function that defines expected spread under our model is submodular. Based on these, we develop an approximation ...
Principle of Entropy Maximization for Nonequilibrium Steady States
Shapiro, Alexander; Stenby, Erling Halfdan
2002-01-01
The goal of this contribution is to find out to what extent the principle of entropy maximization, which serves as a basis for the equilibrium thermodynamics, may be generalized onto non-equilibrium steady states. We prove a theorem that, in the system of thermodynamic coordinates, where entropy...
Optoelectronic plethysmography compared to spirometry during maximal exercise.
Layton, Aimee M; Moran, Sienna L; Garber, Carol Ewing; Armstrong, Hilary F; Basner, Robert C; Thomashow, Byron M; Bartels, Matthew N
2013-01-15
The purpose of this study was to compare simultaneous measurements of tidal volume (Vt) by optoelectronic plethysmography (OEP) and spirometry during a maximal cycling exercise test to quantify possible differences between methods. Vt measured simultaneously by OEP and spirometry was collected during a maximal exercise test in thirty healthy participants. The two methods were compared by linear regression and Bland-Altman analysis at submaximal and maximal exercise. The average difference between the two methods and the mean percentage discrepancy were calculated. Submaximal exercise (SM) and maximal exercise (M) Vt measured by OEP and spirometry had very good correlation, SM R=0.963 (pspirometry. OEP could measure exercise Vt as much as 0.188 L above and -0.017 L below that of spirometry. The discrepancy between measurements was -2.0 ± 7.2% at SM and -2.4 ± 3.9% at M. In conclusion, Vt measurements at during exercise by OEP and spirometry are closely correlated and the difference between measurements was insignificant.
Entropy Maximization and the Spatial Distribution of Species
Haegeman, Bart; Etienne, Rampal S.
Entropy maximization (EM, also known as MaxEnt) is a general inference procedure that originated in statistical mechanics. It has been applied recently to predict ecological patterns, such as species abundance distributions and species-area relationships. It is well known in physics that the EM
On Maximal Subgroups of a Finite Solvable Group
Gritsuk, D V
2011-01-01
The following result is received: Let $H$ be a non-normal maximal subgroup of a finite solvable group $G$ and let $q \\in \\pi(F(H/\\mathrm{Core}_GH))$, then $G$ has a Sylow $q$-subgroup $Q$ such that $N_{G}(Q) \\subseteq H$.
The Effects of Leniency on Maximal Cartel Pricing
Houba, H.E.D.; Motchenkova, E.; Wen, Q.
2009-01-01
We analyze maximal cartel prices in infnitely-repeated oligopoly models under leniency where fines are linked to illegal gains, as often outlined in existing antitrust regulation, and detection probabilities depend on the degree of collusion. We introduce cartel culture that describes how likely
Emotional Control and Instructional Effectiveness: Maximizing a Timeout
Andrews, Staci R.
2015-01-01
This article provides recommendations for best practices for basketball coaches to maximize the instructional effectiveness of a timeout during competition. Practical applications are derived from research findings linking emotional intelligence to effective coaching behaviors. Additionally, recommendations are based on the implications of the…
Quantitative approaches for profit maximization in direct marketing
van der Scheer, H.R.
1998-01-01
An effective direct marketing campaign aims at selecting those targets, offer and communication elements - at the right time - that maximize the net profits. The list of individuals to be mailed, i.e. the targets, is considered to be the most important component. Therefore, a large amount of direct
The Bianchi classification of maximal D=8 gauged supergravities
Bergshoeff, E; Gran, U; Linares, R; Nielsen, M; Ortin, T; Roest, D
2004-01-01
We construct maximal D = 8 gauged supergravities by the reduction of D = 11 supergravity over three-dimensional group manifolds. Such manifolds have been classified by Bianchi. We divide the corresponding gauged supergravities into two classes: class A (with a Lagrangian) and class B (without a Lagr
The Bianchi classification of maximal D = 8 gauged supergravities
Bergshoeff, E.; Gran, U.; Linares, R.; Nielsen, M.; Ortín, T.; Roest, D.
2004-01-01
We construct maximal D = 8 gauged supergravities by the reduction of D = 11 supergravity over three-dimensional group manifolds. Such manifolds have been classified by Bianchi. We divide the corresponding gauged supergravities into two classes: class A (with a Lagrangian) and class B (without a Lagr
Minimal fusion systems with a unique maximal parabolic
Henke, Ellen
2011-01-01
We define minimal fusion systems in a way that every non-solvable fusion system has a section which is minimal. Minimal fusion systems can also be seen as analogs of Thompson's N-groups. In this paper, we consider a minimal fusion system F on a finite p-group S that has a unique maximal p-local s...
Neural network approach for solving the maximal common subgraph problem.
Shoukry, A; Aboutabl, M
1996-01-01
A new formulation of the maximal common subgraph problem (MCSP), that is implemented using a two-stage Hopfield neural network, is given. Relative merits of this proposed formulation, with respect to current neural network-based solutions as well as classical sequential-search-based solutions, are discussed.
Maximally parallel attribute on P Systems:Properties and applications
Chunyi Huang; Xiaoju Dong
2008-01-01
In this paper,we investigate the maximally parallel attribute of P Systems.Some properties of P Systems are introduced,which are the filter property and the enumeration property.The two properties are applied to solving the sorting problem and the Hamilton cycle problem.respectively.