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Sample records for rb feshbach molecules

  1. Formation of ultracold NaRb Feshbach molecules

    International Nuclear Information System (INIS)

    Wang, Fudong; He, Xiaodong; Li, Xiaoke; Zhu, Bing; Chen, Jun; Wang, Dajun

    2015-01-01

    We report the creation of ultracold bosonic 23 Na 87 Rb Feshbach molecules via magneto-association. By ramping the magnetic field across an interspecies Feshbach resonance (FR), at least 4000 molecules can be produced out of the near degenerate ultracold mixture. Fast loss due to inelastic atom–molecule collisions is observed, which limits the pure molecule number, after residual atoms removal, to 1700. The pure molecule sample can live for 21.8(8) ms in the optical trap, long enough for future molecular spectroscopy studies toward coherently transferring to the singlet ro-vibrational ground state, where these molecules are stable against chemical reaction and have a permanent electric dipole moment of 3.3 Debye. We have also measured the Feshbach molecule’s binding energy near the FR by the oscillating magnetic field method and found these molecules have a large closed-channel fraction. (paper)

  2. Role of Feshbach resonances in enhancing the production of deeply bound ultracold LiRb molecules with laser pulses

    Science.gov (United States)

    Gacesa, Marko; Ghosal, Subhas; Côté, Robin

    2010-03-01

    We investigate the possibility of forming deeply bound LiRb molecules in a two-color photoassociation experiment. Ultracold ^6Li and ^87Rb atoms colliding in the vicinity of a magnetic Feshbach resonance are photoassociated into an excited electronic state. A wavepacket is then formed by exciting a few vibrational levels of the excited state and allowed to propagate. We calculate the time-dependent overlaps between the wave packet and the lowest vibrational levels of the ground state. After the optimal overlap is obtained we use the second laser pulse to dump the wave packet and efficiently populate the deeply bound ro-vibrational levels of ^6Li^87Rb in the ground state. The resulting combination of Feshbach-optimized photoassociation (FOPA) with the time-dependent pump-dump approach will produce a large number of stable ultracold molecules in the ground state. This technique is general and applicable to other systems.

  3. Observation of Resonant Effects in Ultracold Collisions between Heteronuclear Feshbach Molecules

    Science.gov (United States)

    Ye, Xin; Wang, Fudong; Zhu, Bing; Guo, Mingyang; Lu, Bo; Wang, Dajun

    2016-05-01

    Magnetic field dependent dimer-dimer collisional losses are studied with ultracold 23 Na87 Rb Feshbach molecules. By ramping the magnetic field across the 347.8 G inter-species Feshbach resonance and removing residual atoms with a magnetic field gradient, ~ 8000 pure NaRb Feshbach molecules with a temperature below 1 μK are produced. By holding the pure molecule sample in a crossed optical dipole trap and measuring the time-dependent loss curves under different magnetic fields near the Feshbach resonance, the dimer-dimer loss rates with respect to the atomic scattering length a are mapped out. We observe a resonant feature at around a = 600a0 and a rising tail at above a = 1600a0 . This behavior resembles previous theoretical works on homonuclear Feshbach molecule, where resonant effects between dimer-dimer collisions tied to tetramer bound states were predicted. Our work shows the possibility of exploring four-body physics within a heteronuclear system. We are supported by Hong Kong RGC General Research Fund no. CUHK403813.

  4. Optical trapping and Feshbach spectroscopy of an ultracold Rb-Cs mixture

    International Nuclear Information System (INIS)

    Pilch, K.

    2009-01-01

    We investigate quantum-mechanical interactions between ultracold rubidium and cesium in an optical trap at temperatures of a few micro kelvin. Our results provide, on the one hand, an experimental key to understand the collisional properties and, on the other hand, a tool to control the interspecies interactions. By performing loss measurements we locate several Feshbach resonances, which provide insight into the energy structure of weakly bound RbCs molecules near the dissociation threshold and allow for the production of such heteronuclear Feshbach molecules. In the future we will transfer these loosely-bound molecules into the absolute internal ground state. The availability of ultracold heteronuclear ground state molecules will open the door to investigate phenomena associated with ultracold polar quantum gases. In our new experimental set-up we are able to trap and cool rubidium and cesium atoms in their lowest internal states. First we load both species into a two-color magneto-optical trap, having full control over the single-species atom number. We extend the technique of degenerate Raman-sideband cooling to a two-color version, which is able to simultaneously cool and polarize both rubidium and cesium. Thereafter we load the atoms into a levitated crossed optical dipole trap. Because of the presence of the gradient magnetic field the trap is highly state selective and consequently provides perfect spin-polarization of the sample. Furthermore, a coincidence of the magnetic-moment-to-mass ratios of the two species allows for simultaneous levitation of both, which assures an almost perfect spatial overlap between the species. We perform Feshbach spectroscopy in two dierent spin channels of the mixture within a magnetic field ranging from 20 to 300 Gauss. In the lowest spin combination of the species we locate 23 interspecies Feshbach resonances, while in a higher spin mixture we find 2 resonances. The high number of resonances found within this range of

  5. Exploring strategies for the production of ultracold RbYb molecules in conservative traps

    Energy Technology Data Exchange (ETDEWEB)

    Bruni, Cristian

    2015-07-14

    Within the scope of this thesis, the production of ultracold molecules at a temperature of a few μK with various isotopes of rubidium (Rb) and ytterbium (Yb) was examined by means of photoassociation spectroscopy and magnetic Feshbach resonances in combined conservative traps. The long-term goal of this experiment is the production of ultracold RbYb molecules in the rovibronic ground state. It was possible to produce electronically excited {sup 87}Rb {sup 176}Yb molecules in a novel hybrid trap (HT) at a combined temperature of 1.7 μK by means of 1-photon photoassociation close to the Rb D1 line at 795 nm. This HT takes advantage of the different magnetic properties of Rb and Yb and allows for independent trapping and manipulation of the atomic species. It combines an Ioffe-Pritchard type magnetic trap for Rb and a near-resonant optical dipole trap for Yb. The excited molecular {sup 2}Π{sub 1/2} state could be characterized further extending previous works in a combined MOT and vibrational levels reaching binding energies up to E{sub b}=-h x 2.2 THz could be assigned by trap-loss spectroscopy. Almost every detected vibrational state consists of two resonances that could be assigned to the molecular analogue of the hyperfine structure of {sup 87}Rb. An important experimental observation is a decrease in hyperfine splitting with increasing binding energy of a vibrational level. For the deepest found vibrational state the hyperfine splitting amounts only 70 % of the atomic value (817 MHz) which emphasizes a gradual passage from weakly to tightly bound molecules. Furthermore, detailed attempts were undertaken to induce magnetic Feshbach resonances in {sup 85}Rb and different Yb isotopes, especially {sup 171}Yb in a crossed optical dipole trap at 1064 nm at temperatures of 10 μK. For this purpose, a homogeneous magnetic field was applied and scanned in small steps over the range of 495 G ∼ 640 G. Unfortunately, our efforts were without success. Additionally, well

  6. Long-Lived Feshbach Molecules in a Three-Dimensional Optical Lattice

    International Nuclear Information System (INIS)

    Thalhammer, G.; Winkler, K.; Lang, F.; Schmid, S.; Denschlag, J. Hecker; Grimm, R.

    2006-01-01

    We have created and trapped a pure sample of 87 Rb 2 Feshbach molecules in a three-dimensional optical lattice. Compared to previous experiments without a lattice, we find dramatic improvements such as long lifetimes of up to 700 ms and a near unit efficiency for converting tightly confined atom pairs into molecules. The lattice shields the trapped molecules from collisions and, thus, overcomes the problem of inelastic decay by vibrational quenching. Furthermore, we have developed an advanced purification scheme that removes residual atoms, resulting in a lattice in which individual sites are either empty or filled with a single molecule in the vibrational ground state of the lattice

  7. Precision spectroscopy with ultracold 87Rb2 triplet molecules

    International Nuclear Information System (INIS)

    Strauss, Christoph

    2011-01-01

    In this thesis I report precision spectroscopy with ultracold 87 Rb 2 triplet molecules where we use lasers to couple the states in different molecular potentials. We study in detail states of the a 3 sum + u and (1) 3 sum + g potentials. These states are of great importance for transferring weakly bound molecules to the ro-vibrational triplet ground state via states of the excited potential. As most experiments start from molecules in their X 1 sum + g ground state, the triplet states were hard to access via dipole transitions and remained largely unexplored. The measurements presented in this thesis are the first detailed study of diatomic 87 Rb 2 molecules in these states. Our experiments start with an ultracold cloud of 87 Rb atoms. We then load this cloud into an optical lattice where we use a magnetic Feshbach resonance at 1007.4 G to perform a Feshbach association. After we have removed all unbound atoms, we end up with a pure sample of weakly bound Feshbach molecules inside the optical lattice. The optical lattice prevents these molecules from colliding with each other which results in molecular lifetimes on the order of a few hundred milliseconds. In the first set of experiments, we use a laser coupling the Feshbach state to the excited (1) 3 sum + g triplet state to map out its low-lying vibrational (v = 0.. 15), rotational, hyperfine, and Zeeman structure. The experimental results are in good agreement with calculations done by Marius Lysebo and Prof. Leif Veseth. We then map out in detail the vibrational, rotational, hyperfine, and Zeeman structure of the a 3 sum + u triplet ground state using dark state spectroscopy with levels in the (1) 3 sum + g potential as an intermediate state. In this scheme we are able to access molecules in triplet states because our Feshbach state has strong triplet character. Interestingly, it happens that some deeply bound states which belong to the X 1 sum + g potential are close to levels in the a 3 sum + u potential. In

  8. Precision spectroscopy with ultracold {sup 87}Rb{sub 2} triplet molecules

    Energy Technology Data Exchange (ETDEWEB)

    Strauss, Christoph

    2011-10-19

    In this thesis I report precision spectroscopy with ultracold {sup 87}Rb{sub 2} triplet molecules where we use lasers to couple the states in different molecular potentials. We study in detail states of the a {sup 3} sum {sup +}{sub u} and (1) {sup 3} sum {sup +}{sub g} potentials. These states are of great importance for transferring weakly bound molecules to the ro-vibrational triplet ground state via states of the excited potential. As most experiments start from molecules in their X {sup 1} sum {sup +}{sub g} ground state, the triplet states were hard to access via dipole transitions and remained largely unexplored. The measurements presented in this thesis are the first detailed study of diatomic {sup 87}Rb{sub 2} molecules in these states. Our experiments start with an ultracold cloud of {sup 87}Rb atoms. We then load this cloud into an optical lattice where we use a magnetic Feshbach resonance at 1007.4 G to perform a Feshbach association. After we have removed all unbound atoms, we end up with a pure sample of weakly bound Feshbach molecules inside the optical lattice. The optical lattice prevents these molecules from colliding with each other which results in molecular lifetimes on the order of a few hundred milliseconds. In the first set of experiments, we use a laser coupling the Feshbach state to the excited (1) {sup 3} sum {sup +}{sub g} triplet state to map out its low-lying vibrational (v = 0.. 15), rotational, hyperfine, and Zeeman structure. The experimental results are in good agreement with calculations done by Marius Lysebo and Prof. Leif Veseth. We then map out in detail the vibrational, rotational, hyperfine, and Zeeman structure of the a {sup 3} sum {sup +}{sub u} triplet ground state using dark state spectroscopy with levels in the (1) {sup 3} sum {sup +}{sub g} potential as an intermediate state. In this scheme we are able to access molecules in triplet states because our Feshbach state has strong triplet character. Interestingly, it

  9. Precision spectroscopy with ultracold {sup 87}Rb{sub 2} triplet molecules

    Energy Technology Data Exchange (ETDEWEB)

    Strauss, Christoph

    2011-10-19

    In this thesis I report precision spectroscopy with ultracold {sup 87}Rb{sub 2} triplet molecules where we use lasers to couple the states in different molecular potentials. We study in detail states of the a {sup 3} sum {sup +}{sub u} and (1) {sup 3} sum {sup +}{sub g} potentials. These states are of great importance for transferring weakly bound molecules to the ro-vibrational triplet ground state via states of the excited potential. As most experiments start from molecules in their X {sup 1} sum {sup +}{sub g} ground state, the triplet states were hard to access via dipole transitions and remained largely unexplored. The measurements presented in this thesis are the first detailed study of diatomic {sup 87}Rb{sub 2} molecules in these states. Our experiments start with an ultracold cloud of {sup 87}Rb atoms. We then load this cloud into an optical lattice where we use a magnetic Feshbach resonance at 1007.4 G to perform a Feshbach association. After we have removed all unbound atoms, we end up with a pure sample of weakly bound Feshbach molecules inside the optical lattice. The optical lattice prevents these molecules from colliding with each other which results in molecular lifetimes on the order of a few hundred milliseconds. In the first set of experiments, we use a laser coupling the Feshbach state to the excited (1) {sup 3} sum {sup +}{sub g} triplet state to map out its low-lying vibrational (v = 0.. 15), rotational, hyperfine, and Zeeman structure. The experimental results are in good agreement with calculations done by Marius Lysebo and Prof. Leif Veseth. We then map out in detail the vibrational, rotational, hyperfine, and Zeeman structure of the a {sup 3} sum {sup +}{sub u} triplet ground state using dark state spectroscopy with levels in the (1) {sup 3} sum {sup +}{sub g} potential as an intermediate state. In this scheme we are able to access molecules in triplet states because our Feshbach state has strong triplet character. Interestingly, it

  10. Electric-field-modified Feshbach resonances in ultracold atom–molecule collision

    International Nuclear Information System (INIS)

    Cheng Dong; Li Ya; Feng Eryin; Huang Wuying

    2017-01-01

    We present a detailed analysis of near zero-energy Feshbach resonances in ultracold collisions of atom and molecule, taking the He–PH system as an example, subject to superimposed electric and magnetic static fields. We find that the electric field can induce Feshbach resonance which cannot occur when only a magnetic field is applied, through couplings of the adjacent rotational states of different parities. We show that the electric field can shift the position of the magnetic Feshbach resonance, and change the amplitude of resonance significantly. Finally, we demonstrate that, for narrow magnetic Feshbach resonance as in most cases of ultracold atom–molecule collision, the electric field may be used to modulate the resonance, because the width of resonance in electric field scale is relatively larger than that in magnetic field scale. (paper)

  11. High-resolution internal state control of ultracold 23Na87Rb molecules

    Science.gov (United States)

    Guo, Mingyang; Ye, Xin; He, Junyu; Quéméner, Goulven; Wang, Dajun

    2018-02-01

    We report the full internal state control of ultracold 23Na87Rb molecules, including vibrational, rotational, and hyperfine degrees of freedom. Starting from a sample of weakly bound Feshbach molecules, we realize the creation of molecules in single hyperfine levels of both the rovibrational ground and excited states with a high-efficiency and high-resolution stimulated Raman adiabatic passage. This capability brings broad possibilities for investigating ultracold polar molecules with different chemical reactivities and interactions with a single molecular species. Moreover, starting from the rovibrational and hyperfine ground state, we achieve rotational and hyperfine control with one- and two-photon microwave spectroscopy to reach levels not accessible by the stimulated Raman transfer. The combination of these two techniques results in complete control over the internal state of ultracold polar molecules, which paves the way to study state-dependent molecular collisions and state-controlled chemical reactions.

  12. Collective molecule formation in a degenerate Fermi gas via a Feshbach resonance

    International Nuclear Information System (INIS)

    Javanainen, Juha; Kostrun, Marijan; Zheng Yi; Carmichael, Andrew; Shrestha, Uttam; Meinel, Patrick J.; Mackie, Matt; Dannenberg, Olavi; Suominen, Kalle-Antti

    2004-01-01

    We model collisionless collective conversion of a degenerate Fermi gas of atoms into bosonic molecules via a Feshbach resonance, treating the bosonic molecules as a classical field and seeding the pairing amplitudes with random phases. A dynamical instability of the Fermi sea against association with molecules drives the conversion. The model qualitatively reproduces several experimental observations [Regal et al., Nature (London) 424, 47 (2003)]. We predict that the initial temperature of the Fermi gas sets the limit for the efficiency of atom-molecule conversion

  13. Molecule condensate production from an atomic Bose-Einstein condensate via Feshbach scattering in an optical lattice: Gap solitons

    International Nuclear Information System (INIS)

    Tasgal, Richard S.; Menabde, G.; Band, Y. B.

    2006-01-01

    We propose a scheme for making a Bose-Einstein condensate (BEC) of molecules from a BEC of atoms in a strongly confining two-dimensional optical lattice and a weak one-dimensional optical lattice in the third dimension. The stable solutions obtained for the order parameters take the form of a different type of gap soliton, with both atomic and molecular BECs, and also standard gap solitons with only a molecular BEC. The strongly confining dimensions of the lattice stabilize the BEC against inelastic energy transfer in atom-molecule collisions. The solitons with atoms and molecules may be obtained by starting with an atomic BEC, and gradually tuning the resonance by changing the external magnetic-field strength until the desired atom-molecule soliton is obtained. A gap soliton of a BEC of only molecules may be obtained nonadiabatically by starting from an atom-only gap soliton, far from a Feshbach resonance and adjusting the magnetic field to near Feshbach resonance. After a period of time in which the dimer field grows, change the magnetic field such that the detuning is large and negative and Feshbach effects wash out, turn off the optical lattice in phase with the atomic BEC, and turn on an optical lattice in phase with the molecules. The atoms disperse, leaving a gap soliton composed of a molecular BEC. Regarding instabilities in the dimension of the weak optical lattice, the solitons which are comprised of both atoms and molecules are sometimes stable and sometimes unstable--we present numerically obtained results. Gap solitons comprised of only molecules have the same stability properties as the standard gap solitons: stable from frequencies slightly below the middle of the band gap to the top, and unstable below that point. Instabilities are only weakly affected by the soliton velocities, and all instabilities are oscillatory

  14. Multiple-state Feshbach resonances mediated by high-order couplings

    International Nuclear Information System (INIS)

    Hemming, Christopher J.; Krems, Roman V.

    2008-01-01

    We present a study of multistate Feshbach resonances mediated by high-order couplings. Our analysis focuses on a system with one open scattering state and multiple bound states. The scattering state is coupled to one off-resonant bound state and multiple Feshbach resonances are induced by a sequence of indirect couplings between the closed channels. We derive a general recursive expression that can be used to fit the experimental data on multistate Feshbach resonances involving one continuum state and several bound states and present numerical solutions for several model systems. Our results elucidate general features of multistate Feshbach resonances induced by high-order couplings and suggest mechanisms for controlling collisions of ultracold atoms and molecules with external fields

  15. A Mott-like State of Molecules

    International Nuclear Information System (INIS)

    Duerr, S.; Volz, T.; Syassen, N.; Bauer, D. M.; Hansis, E.; Rempe, G.

    2006-01-01

    We prepare a quantum state where each site of an optical lattice is occupied by exactly one molecule. This is the same quantum state as in a Mott insulator of molecules in the limit of negligible tunneling. Unlike previous Mott insulators, our system consists of molecules which can collide inelastically. In the absence of the optical lattice these collisions would lead to fast loss of the molecules from the sample. To prepare the state, we start from a Mott insulator of atomic 87Rb with a central region, where each lattice site is occupied by exactly two atoms. We then associate molecules using a Feshbach resonance. Remaining atoms can be removed using blast light. Our method does not rely on the molecule-molecule interaction properties and is therefore applicable to many systems

  16. Satellite bands of the RbCs molecule in the range of highly excited states

    Energy Technology Data Exchange (ETDEWEB)

    Rakić, Mario; Beuc, Robert; Skenderović, Hrvoje, E-mail: hrvoje@ifs.hr [Institute of Physics, Bijenička cesta 46, Zagreb 10000 (Croatia); Bouloufa-Maafa, Nadia; Dulieu, Olivier; Vexiau, Romain [Laboratoire Aimé Cotton, CNRS, Université Paris-Sud, ENS Cachan, Université Paris-Saclay, Bât. 505, Campus d’Orsay, Orsay Cedex 91405 (France); Pichler, Goran [Physics Department, Kuwait University, PO Box 5969, Safat—13060 (Kuwait)

    2016-05-28

    We report on the observation of three RbCs satellite bands in the blue and green ranges of the visible spectrum. Absorption measurements are performed using all-sapphire cell filled with a mixture of Rb and Cs. We compare high resolution absorption spectrum of Rb-Cs vapor mixture with pure Rb and Cs vapor spectra from the literature. After detailed analysis, the new satellite bands of RbCs molecule at 418.3 nm, 468.3, and 527.5 nm are identified. The origin of these bands is discussed by direct comparison with difference potentials derived from quantum chemistry calculations of RbCs potential energy curves. These bands originate from the lower Rydberg states of the RbCs molecule. This study thus provides further insight into photoassociation of lower Rydberg molecular states, approximately between Cs(7s) + Rb(5s) and Cs(6s) + Rb(6p) asymptotes, in ultracold gases.

  17. Ultracold fermion cooling cycle using heteronuclear Feshbach resonances

    DEFF Research Database (Denmark)

    Morales, M. A.; Nygaard, Nicolai; Williams, J. E.

    2005-01-01

    We consider an ideal gas of Bose and Fermi atoms in a harmonic trap, with a Feshbach resonance in the interspecies atomic scattering that can lead to the formation of fermionic molecules. We map out the phase diagram for this three-component mixture in chemical and thermal equilibrium. Considering...... adiabatic association and dissociation of the molecules, we identify a possible cooling cycle, which in ideal circumstances can yield an exponential increase of the phase-space density....

  18. Magnetic field modification of ultracold molecule-molecule collisions

    International Nuclear Information System (INIS)

    Tscherbul, T V; Suleimanov, Yu V; Aquilanti, V; Krems, R V

    2009-01-01

    We present an accurate quantum mechanical study of molecule-molecule collisions in the presence of a magnetic field. The work focuses on the analysis of elastic scattering and spin relaxation in collisions of O 2 ( 3 Σ g - ) molecules at cold (∼0.1 K) and ultracold (∼10 -6 K) temperatures. Our calculations show that magnetic spin relaxation in molecule-molecule collisions is extremely efficient except at magnetic fields below 1 mT. The rate constant for spin relaxation at T=0.1 K and a magnetic field of 0.1 T is found to be as large as 6.1x10 -11 cm -3 s -1 . The magnetic field dependence of elastic and inelastic scattering cross sections at ultracold temperatures is dominated by a manifold of Feshbach resonances with the density of ∼100 resonances per Tesla for collisions of molecules in the absolute ground state. This suggests that the scattering length of ultracold molecules in the absolute ground state can be effectively tuned in a very wide range of magnetic fields. Our calculations demonstrate that the number and properties of the magnetic Feshbach resonances are dramatically different for molecules in the absolute ground and excited spin states. The density of Feshbach resonances for molecule-molecule scattering in the low-field-seeking Zeeman state is reduced by a factor of 10.

  19. Polaronic and dressed molecular states in orbital Feshbach resonances

    Science.gov (United States)

    Xu, Junjun; Qi, Ran

    2018-04-01

    We consider the impurity problem in an orbital Feshbach resonance (OFR), with a single excited clock state | e ↑⟩ atom immersed in a Fermi sea of electronic ground state | g ↓⟩. We calculate the polaron effective mass and quasi-particle residue, as well as the polaron to molecule transition. By including one particle-hole excitation in the molecular state, we find significant correction to the transition point. This transition point moves toward the BCS side for increasing particle densities, which suggests that the corresponding many-body physics is similar to a narrow resonance.

  20. Measurement of optical Feshbach resonances in an ideal gas.

    Science.gov (United States)

    Blatt, S; Nicholson, T L; Bloom, B J; Williams, J R; Thomsen, J W; Julienne, P S; Ye, J

    2011-08-12

    Using a narrow intercombination line in alkaline earth atoms to mitigate large inelastic losses, we explore the optical Feshbach resonance effect in an ultracold gas of bosonic (88)Sr. A systematic measurement of three resonances allows precise determinations of the optical Feshbach resonance strength and scaling law, in agreement with coupled-channel theory. Resonant enhancement of the complex scattering length leads to thermalization mediated by elastic and inelastic collisions in an otherwise ideal gas. Optical Feshbach resonance could be used to control atomic interactions with high spatial and temporal resolution.

  1. Measurement of Optical Feshbach Resonances in an Ideal Gas

    International Nuclear Information System (INIS)

    Blatt, S.; Nicholson, T. L.; Bloom, B. J.; Williams, J. R.; Thomsen, J. W.; Ye, J.; Julienne, P. S.

    2011-01-01

    Using a narrow intercombination line in alkaline earth atoms to mitigate large inelastic losses, we explore the optical Feshbach resonance effect in an ultracold gas of bosonic 88 Sr. A systematic measurement of three resonances allows precise determinations of the optical Feshbach resonance strength and scaling law, in agreement with coupled-channel theory. Resonant enhancement of the complex scattering length leads to thermalization mediated by elastic and inelastic collisions in an otherwise ideal gas. Optical Feshbach resonance could be used to control atomic interactions with high spatial and temporal resolution.

  2. Ultracold Polar Molecules

    Science.gov (United States)

    2016-04-01

    done was that the Innsbruck experimental group (under Hanns-Christoph Nägerl and Rudi Grimm ) had measured a Feshbach resonance spec- trum for 87Rb + Cs...R. Rameshan, F. Ferlaino, R. Grimm , H.-C. Nägerl, C. R. Le Sueur, J. M. Hutson, P. S. Julienne, S. Kotochigova, and E. Tiemann, Phys. Rev. A 85... Grimm , and H.-C. Nägerl, Phys. Rev. Lett. 113, 205301 (2014). [4] P. K. Molony, P. D. Gregory, Z. Ji, B. Lu, M. P. Köppinger, C. R. Le Sueur, C. L

  3. Investigation on ultracold RbCs molecules in (2)0{sup +} long-range state below the Rb(5S{sub 1/2}) + Cs(6P{sub 1/2}) asymptote by high resolution photoassociation spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Jinpeng; Ji, Zhonghua; Li, Zhonghao; Zhao, Yanting, E-mail: zhaoyt@sxu.edu.cn; Xiao, Liantuan; Jia, Suotang [State Key Laboratory of Quantum Optics and Quantum Optics Devices, Institute of Laser Spectroscopy, Shanxi University, Taiyuan 030006 (China)

    2015-07-28

    We present high resolution photoassociation spectroscopy of RbCs molecules in (2)0{sup +} long-range state below the Rb(5S{sub 1/2}) + Cs(6P{sub 1/2}) asymptote and derive the corresponding C{sub 6} coefficient, which is used to revise the potential energy curves. The excited state molecules are produced in a dual-species dark spontaneous force optical trap and detected by ionizing ground state molecules after spontaneous decay, using a high sensitive time-of-flight mass spectrum. With the help of resonance-enhanced two-photon ionization technique, we obtain considerable high resolution photoassociation spectrum with rovibrational states, some of which have never been observed before. By applying the LeRoy-Bernstein method, we assign the vibrational quantum numbers and deduce C{sub 6} coefficient, which agrees with the theoretical value of A{sup 1}Σ{sup +} state correlated to Rb(5S{sub 1/2}) + Cs(6P{sub 1/2}) asymptote. The obtained C{sub 6} coefficient is used to revise the long-range potential energy curve for (2)0{sup +} state, which possesses unique A − b mixing characteristic and can be a good candidate for the production of absolutely ground state molecule.

  4. Production and spectroscopy of ultracold YbRb* molecules

    International Nuclear Information System (INIS)

    Nemitz, Nils

    2008-11-01

    This thesis describes the formation of electronically excited but translationally cold molecules formed from rubidium atoms and two isotopes of ytterbium ( 176 Yb and 174 Yb) by means of photoassociation. The experiments were performed in a combined MOT with 10 9 rubidium atoms and 2.10 6 ytterbium atoms at temperatures of less than 1 mK. Photoassociation lines were found by trap loss spectroscopy throughout a wavelength range of 2 nm near the 795 nm D1 transition in rubidium. The majority of lines belong to two vibrational series in the excited YbRb * molecule, converging on a system of a ground state ytterbium atom and an excited rubidium atom. The strong variation of line strength between different vibrational lines is explained through the Franck-Condon principle. An improved version of the Leroy-Bernstein equation was used to extract the leading dispersion coefficient of the potential from the vibrational progression. Most of the observed lines show a resolved rotational structure as expected from a basic quantum mechanical model. The series terminates with the third or forth rotational component due to the ground state centrifugal barrier.The measured rotational constants agree very well with calculations based on the C 6 coefficient. The discovery of a splitting of the rotational components into subcomponents indicates an uncommon angular momentum coupling described by Hund's case. Variations in the depth of the subcomponents indicates a similar splitting in the ground state, with the energies of the substates based on the alignment of the rubidium atom's magnetic dipole moment relative to the angular momentum carried by an approaching ytterbium atom. This creates an additional ground state barrier, partially suppressing some of the subcomponents. Using a rate equation model developed for this purpose, a maximum formation rate of 2.5.10 6 molecules per second was calculated over the volume of the entire trap. The work presented here is an important step on

  5. Rovibrational dynamics of the RbCs molecule in static electric fields. Classical study

    Energy Technology Data Exchange (ETDEWEB)

    Arnaiz, Pedro F.; Iñarrea, Manuel [Área de Física, Universidad de la Rioja, E-26006 Logroño (Spain); Salas, J. Pablo, E-mail: josepablo.salas@unirioja.es [Área de Física, Universidad de la Rioja, E-26006 Logroño (Spain)

    2012-04-02

    We study the classical dynamics of the RbCs molecule in the presence of a static electric field. Under the Born–Oppenheimer approximation, we perform a rovibrational investigation which includes the interaction of the field with the molecular polarizability. The stability of the equilibrium points and the phase space structure of the system are explored in detail. We find that, for strong electric fields or for energies close to the dissociation threshold, the molecular polarizability causes relevant effects on the system dynamics. -- Highlights: ► We study the classical rovibrational dynamics of the alkali polar dimer RbCs. ► In the model we consider the interaction of the field with the molecular polarizability. ► The potential energy surface is studied depending on the electric field strength. ► Using surfaces of section we study the phase space structure. ► We find that the molecular polarizability causes relevant effects on the system dynamics.

  6. Rovibrational dynamics of the RbCs molecule in static electric fields. Classical study

    International Nuclear Information System (INIS)

    Arnaiz, Pedro F.; Iñarrea, Manuel; Salas, J. Pablo

    2012-01-01

    We study the classical dynamics of the RbCs molecule in the presence of a static electric field. Under the Born–Oppenheimer approximation, we perform a rovibrational investigation which includes the interaction of the field with the molecular polarizability. The stability of the equilibrium points and the phase space structure of the system are explored in detail. We find that, for strong electric fields or for energies close to the dissociation threshold, the molecular polarizability causes relevant effects on the system dynamics. -- Highlights: ► We study the classical rovibrational dynamics of the alkali polar dimer RbCs. ► In the model we consider the interaction of the field with the molecular polarizability. ► The potential energy surface is studied depending on the electric field strength. ► Using surfaces of section we study the phase space structure. ► We find that the molecular polarizability causes relevant effects on the system dynamics.

  7. P-wave Feshbach resonances of ultracold 6Li

    International Nuclear Information System (INIS)

    Zhang, J.; Kempen, E.G.M. van; Bourdel, T.; Cubizolles, J.; Chevy, F.; Teichmann, M.; Tarruell, L.; Salomon, C.; Khaykovich, L.; Kokkelmans, S.J.J.M.F.

    2004-01-01

    We report the observation of three p-wave Feshbach resonances of 6 Li atoms in the lowest hyperfine state f=1/2. The positions of the resonances are in good agreement with theory. We study the lifetime of the cloud in the vicinity of the Feshbach resonances and show that, depending on the spin states, two- or three-body mechanisms are at play. In the case of dipolar losses, we observe a nontrivial temperature dependence that is well explained by a simple model

  8. An efficient nonlinear Feshbach engine

    Science.gov (United States)

    Li, Jing; Fogarty, Thomás; Campbell, Steve; Chen, Xi; Busch, Thomas

    2018-01-01

    We investigate a thermodynamic cycle using a Bose-Einstein condensate (BEC) with nonlinear interactions as the working medium. Exploiting Feshbach resonances to change the interaction strength of the BEC allows us to produce work by expanding and compressing the gas. To ensure a large power output from this engine these strokes must be performed on a short timescale, however such non-adiabatic strokes can create irreversible work which degrades the engine’s efficiency. To combat this, we design a shortcut to adiabaticity which can achieve an adiabatic-like evolution within a finite time, therefore significantly reducing the out-of-equilibrium excitations in the BEC. We investigate the effect of the shortcut to adiabaticity on the efficiency and power output of the engine and show that the tunable nonlinearity strength, modulated by Feshbach resonances, serves as a useful tool to enhance the system’s performance.

  9. Systematic assignment of Feshbach resonances via an asymptotic bound state model

    NARCIS (Netherlands)

    Goosen, M.; Kokkelmans, SJ.J.M.F.

    2008-01-01

    We present an Asymptotic Bound state Model (ABM), which is useful to predict Feshbach resonances. The model utilizes asymptotic properties of the interaction potentials to represent coupled molecular wavefunctions. The bound states of this system give rise to Feshbach resonances, localized at the

  10. Dissociation and decay of ultracold sodium molecules

    International Nuclear Information System (INIS)

    Mukaiyama, T.; Abo-Shaeer, J.R.; Xu, K.; Chin, J.K.; Ketterle, W.

    2004-01-01

    The dissociation of ultracold molecules was studied by ramping an external magnetic field through a Feshbach resonance. The observed dissociation energies directly yielded the strength of the atom-molecule coupling. They showed nonlinear dependence on the ramp speed. This was explained by a Wigner threshold law which predicts that the decay rate of the molecules above threshold increases with the density of states. In addition, inelastic molecule-molecule and molecule-atom collisions were characterized

  11. Production and spectroscopy of ultracold YbRb{sup *} molecules

    Energy Technology Data Exchange (ETDEWEB)

    Nemitz, Nils

    2008-11-15

    This thesis describes the formation of electronically excited but translationally cold molecules formed from rubidium atoms and two isotopes of ytterbium ({sup 176}Yb and {sup 174}Yb) by means of photoassociation. The experiments were performed in a combined MOT with 10{sup 9} rubidium atoms and 2.10{sup 6} ytterbium atoms at temperatures of less than 1 mK. Photoassociation lines were found by trap loss spectroscopy throughout a wavelength range of 2 nm near the 795 nm D1 transition in rubidium. The majority of lines belong to two vibrational series in the excited YbRb{sup *} molecule, converging on a system of a ground state ytterbium atom and an excited rubidium atom. The strong variation of line strength between different vibrational lines is explained through the Franck-Condon principle. An improved version of the Leroy-Bernstein equation was used to extract the leading dispersion coefficient of the potential from the vibrational progression. Most of the observed lines show a resolved rotational structure as expected from a basic quantum mechanical model. The series terminates with the third or forth rotational component due to the ground state centrifugal barrier.The measured rotational constants agree very well with calculations based on the C{sub 6} coefficient. The discovery of a splitting of the rotational components into subcomponents indicates an uncommon angular momentum coupling described by Hund's case. Variations in the depth of the subcomponents indicates a similar splitting in the ground state, with the energies of the substates based on the alignment of the rubidium atom's magnetic dipole moment relative to the angular momentum carried by an approaching ytterbium atom. This creates an additional ground state barrier, partially suppressing some of the subcomponents. Using a rate equation model developed for this purpose, a maximum formation rate of 2.5.10{sup 6} molecules per second was calculated over the volume of the entire trap. The

  12. Dressed molecules in resonantly interacting ultracold atomic Fermi gases

    NARCIS (Netherlands)

    Falco, G.M.; Stoof, H.T.C.

    2007-01-01

    We present a detailed analysis of the two-channel atom-molecule effective Hamiltonian for an ultracold two-component homogeneous Fermi gas interacting near a Feshbach resonance. We particularly focus on the two-body and many-body properties of the dressed molecules in such a gas. An exact result

  13. RB1CC1 activates RB1 pathway and inhibits proliferation and cologenic survival in human cancer.

    Directory of Open Access Journals (Sweden)

    Tokuhiro Chano

    2010-06-01

    Full Text Available RB1-inducible coiled-coil 1 (RB1CC1, also known as FIP200 plays a role in the enhancement of the RB1 pathway through the direct binding to a GC-rich region 201bp upstream (from the initiation ATG of the RB1 promoter. Here, we identified hSNF5 and p53 as the binding partners of RB1CC1 by immunoprecipitation and immunofluorescence assays. Interaction between these molecules and the RB1 pathway was analyzed by the assays of chromatin immunoprecipitation, luciferase-reporter, reverse transcription-polymerase chain reaction and immunoblot. The tumor growth suppression by RB1CC1 was evaluated by flow cytometry or by a cell growth assay. The nuclear RB1CC1 complex involving hSNF5 and/or p53 activated transcription of RB1, p16 and p21, and suppressed tumor cell growth. Furthermore, nuclear RB1CC1 expression significantly correlated with those of RB1 and p16 in breast cancer tissue in vivo, and the Ki-67 proliferation index was dependent on p53 as well as RB1CC1. The present study indicates that RB1CC1 together with hSNF5 and/or p53 enhances the RB1 pathway through transcriptional activation of RB1, p16 and p21. Evaluation of RB1CC1 expression combined with RB1 and p53 status is expected to provide useful information in clinical practice and future therapeutic strategies in breast cancer.

  14. Feshbach resonances in cold collisions of potassium atoms

    International Nuclear Information System (INIS)

    Bambini, A.; Geltman, S.

    2002-01-01

    In this paper we briefly review the basic steps that allow the calculation of the scattering length in the collision of two alkali-metal atoms in a well defined magnetic polarization state, and in the presence of a static magnetic field. Calculations are actually done for the low-field seeking state F=1, μ F =-1 of bosonic potassium atoms. The electrostatic potentials obtained through Rydberg-Klein-Rees data are connected to a dispersive, long range tail in which the dominant dipole-dipole C 6 term may take different values within a specified range. We show the occurrence of Feshbach resonances in the ultra cold collision of two identical atoms, belonging either to the bosonic species 39 K or 41 K. Our results demonstrate that there is a range of C 6 values for which the collision of two 39 K atoms displays a single resonance, while for other values of C 6 no resonance occurs. On the other hand, Feshbach resonances are present in the collision of two 41 K atoms for almost all values of the dispersion coefficient C 6 in that range. We also show the origin of the different types of Feshbach resonances that occur in the cold collision of two 41 K atoms. The detection of such resonances can help establish the actual value of the dispersive coefficient

  15. Determination of dissociation enthalpies of KPbF3, RbPbF3, CsPbF3 complex molecules

    International Nuclear Information System (INIS)

    Boltalin, A.I.; Rykov, A.N.; Korenev, Yu.M.

    1990-01-01

    Isomolecular reactions in MPbF 3(g) -BeF 2(g) systems where M=K, Rb, Cs are studied using Knudsen effusion technique with mass-spectral analysis of evaporation products. Enthalpy values of dissociation of MPbF 3 molecules per lead difluoride and alkali metal fluoride which are equal to 212.1±12.6 kJ/mol for CsPbF 3 are determined

  16. Feshbach and Efimov Resonances in A 6Li- 133Cs Atomic Mixture

    Science.gov (United States)

    Johansen, Jacob

    This thesis reports measurements of interactions in Fermi-Bose 6Li-133Cs mixtures. Precise control of this Bose-Fermi mixture allowed us to probe few-body physics in regimes which were previously inaccessible. In particular, we performed the first model-independent test of geometric scaling of Efimov physics and probed Efimov resonances farther in the weakly coupled, narrow resonance regime than previously possible. For this work, we built a new apparatus which overcomes the many challenges faced by Li-Cs mixtures. We developed several novel dipole trapping schemes which overcome the difficulties of mixing Li and Cs, including the large differences in initial trapping and cooling between these atomic species and a large differential gravitational sag. We also achieved part per million level magnetic field control near 900 G, necessary for the precise measurements near narrow Feshbach resonances undertaken in this thesis, by pioneering a tomographic magnetic field calibration technique. With this apparatus, we first probed the Feshbach resonances of the Li-Cs mixture. This is an essential first step, allowing us to understand and control the two-body interactions between our atoms. Next we began to probe Efimov physics, an important three-body phenomenon wherein an infinite series of three-body bound states arise near two-body scattering resonances, such as Feshbach resonances. We demonstrated the universal scaling expected theoretically for Efimov states near a Feshbach resonance. This task was made feasible in our system by a reduced Efimov scaling constant, yet still required precise magnetic field control. Finally, additional universal behavior of the first Efimov resonance has been observed empirically in a variety of atomic systems. While theory has explained this observed universality, predictions also indicate departures for narrow Feshbach resonances, contrary to previous experimental results. By further improving our magnetic field control to probe a very

  17. Fractional Bateman—Feshbach Tikochinsky Oscillator

    Science.gov (United States)

    Dumitru, Baleanu; Jihad, H. Asad; Ivo, Petras

    2014-02-01

    In the last few years the numerical methods for solving the fractional differential equations started to be applied intensively to real world phenomena. Having these things in mind in this manuscript we focus on the fractional Lagrangian and Hamiltonian of the complex Bateman—Feshbach Tikochinsky oscillator. The numerical analysis of the corresponding fractional Euler-Lagrange equations is given within the Grünwald—Letnikov approach, which is power series expansion of the generating function.

  18. Theoretical study of the influence of intense femtosecond laser field on the evolution of the wave packet and the population of NaRb molecule

    International Nuclear Information System (INIS)

    Ning, Ma; Mei-Shan, Wang; Chuan-Lu, Yang; Xiao-Guang, Ma; De-Hua, Wang

    2010-01-01

    Employing the two-state model and the time-dependent wave packet method, we have investigated the influences of the parameters of the intense femtosecond laser field on the evolution of the wave packet, as well as the population of ground and double-minimum electronic states of the NaRb molecule. For the different laser wavelengths, the evolution of the wave packet of 6 1 σ + state with time and internuclear distance is different, and the different laser intensity brings different influences on the population of the electronic states of the NaRb molecule. One can control the evolutions of wave packet and the population in each state by varying the laser parameters appropriately, which will be a benefit for the light manipulation of atomic and molecular processes. (atomic and molecular physics)

  19. Fractional Bateman—Feshbach Tikochinsky Oscillator

    International Nuclear Information System (INIS)

    Baleanu, Dumitru; Asad, Jihad H.; Petras Ivo

    2014-01-01

    In the last few years the numerical methods for solving the fractional differential equations started to be applied intensively to real world phenomena. Having these things in mind in this manuscript we focus on the fractional Lagrangian and Hamiltonian of the complex Bateman—Feshbach Tikochinsky oscillator. The numerical analysis of the corresponding fractional Euler-Lagrange equations is given within the Grünwald—Letnikov approach, which is power series expansion of the generating function. (physics of elementary particles and fields)

  20. Feshbach shape resonance for high Tc superconductivity in superlattices of nanotubes

    International Nuclear Information System (INIS)

    Bianconi, Antonio

    2006-01-01

    The case of a Feshbach shape resonance in the pairing mechanism for high T c superconductivity in a crystalline lattice of doped metallic nanotubes is described. The superlattice of doped metallic nanotubes provides a superconductor with a strongly asymmetric gap. The disparity and different spatial locations of the wave functions of electrons in different subbands at the Fermi level should suppress the single electron impurity interband scattering giving multiband superconductivity in the clean limit. The Feshbach resonances will arise from the component single-particle wave functions out of which the electron pair wave function is constructed: pairs of wave functions which are time inverse of each other. The Feshbach shape resonance increases the critical temperature by tuning the chemical potential at the Lifshitz electronic topological transition (ETT) where the Fermi surface of one of the bands changes from the one dimensional (1D) to the two dimensional (2D) topology (1D/2D ETT). (copyright 2006 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (Abstract Copyright [2006], Wiley Periodicals, Inc.)

  1. Emission characteristics of Xe-RbBr plasma

    Science.gov (United States)

    Heneral, A. A.; Avtaeva, S. V.

    2017-12-01

    The luminescence spectra of the longitudinal pulsed-periodic discharge in Xe-RbBr gas-vapour mixtures at low pressures are experimentally studied. Conditions for obtaining strong UV radiation of XeBr* exiplex molecules in the spectral range of 200-425 nm are found. The greatest output of the XeBr* UV radiation is provided at temperature of the gas-discharge tube walls of ~1000 K. The maximum UV emission power of the whole plasma volume is 4.8 W. Formation of XeBr* exciplex molecules in the pulsed-periodic discharge in Xe-RbBr gas-vapour mixtures at low pressures is discussed.

  2. Analysis of experimental positron-molecule binding energies

    International Nuclear Information System (INIS)

    Danielson, J R; Surko, C M; Young, J A

    2010-01-01

    Experiments show that positron annihilation on molecules frequently occurs via capture into vibrational Feshbach resonances. In these cases, the downshifts in the annihilation spectra from the vibrational mode spectra provide measures of the positron-molecule binding energies. An analysis of these binding energy data is presented in terms of the molecular dipole polarizability, the permanent dipole moment, and the number of π bonds in aromatic molecules. The results of this analysis are in reasonably good agreement with other information about positron-molecule bound states. Predictions for other targets and promising candidate molecules for further investigation are discussed.

  3. Global transmission coefficients in Hauser-Feshbach calculations for astrophysics

    Energy Technology Data Exchange (ETDEWEB)

    Rauscher, T [Inst. fuer Physik, Univ. Basel, Basel (Switzerland)

    1998-06-01

    The current status of optical potentials employed in the prediction of thermonuclear reaction rates for astrophysics in the Hauser-Feshbach formalism is discussed. Special emphasis is put on {alpha}+nucleus potentials. Further experimental efforts are motivated. (orig.)

  4. EDITORIAL: Focus on Cold and Ultracold Molecules FOCUS ON COLD AND ULTRACOLD MOLECULES

    Science.gov (United States)

    Carr, Lincoln D.; Ye, Jun

    2009-05-01

    Robin Côté Single-photon molecular cooling Edvardas Narevicius, S Travis Bannerman and Mark G Raizen Quantum simulations of extended Hubbard models with dipolar crystals M Ortner, A Micheli, G Pupillo and P Zoller Collisional and molecular spectroscopy in an ultracold Bose-Bose mixture G Thalhammer, G Barontini, J Catani, F Rabatti, C Weber, A Simoni, F Minardi and M Inguscio Multi-channel modelling of the formation of vibrationally cold polar KRb molecules Svetlana Kotochigova, Eite Tiesinga and Paul S Julienne Formation of ultracold, highly polar X1Σ+ NaCs molecules C Haimberger, J Kleinert, P Zabawa, A Wakim and N P Bigelow Quantum polarization spectroscopy of correlations in attractive fermionic gases T Roscilde, M Rodríguez, K Eckert, O Romero-Isart, M Lewenstein, E Polzik and A Sanpera Inelastic semiclassical collisions in cold dipolar gases Michael Cavagnero and Catherine Newell Quasi-universal dipolar scattering in cold and ultracold gases J L Bohn, M Cavagnero and C Ticknor Stark deceleration of lithium hydride molecules S K Tokunaga, J M Dyne, E A Hinds and M R Tarbutt Molecular vibrational cooling by optical pumping with shaped femtosecond pulses D Sofikitis, S Weber, A Fioretti, R Horchani, M Allegrini, B Chatel, D Comparat and P Pillet Deeply bound ultracold molecules in an optical lattice Johann G Danzl, Manfred J Mark, Elmar Haller, Mattias Gustavsson, Russell Hart, Andreas Liem, Holger Zellmer and Hanns-Christoph Nägerl Toward the production of quantum degenerate bosonic polar molecules, 41K87Rb K Aikawa, D Akamatsu, J Kobayashi, M Ueda, T Kishimoto and S Inouye Influence of a Feshbach resonance on the photoassociation of LiCs J Deiglmayr, P Pellegrini, A Grochola, M Repp, R Côté, O Dulieu, R Wester and M Weidemüller The kinematic cooling of molecules with laser-cooled atoms Ken Takase, Larry A Rahn, David W Chandler and Kevin E Strecker Coherent collapses of dipolar Bose-Einstein condensates for different trap geometries J Metz, T Lahaye, B Fr

  5. Novel Feshbach resonances in a ^40K spin-mixture

    Science.gov (United States)

    Walraven, J. T. M.; Ludewig, A.; Tiecke, T. G.

    2010-03-01

    We present experimental results on novel s-wave Feshbach resonances in ^40K spin-mixtures. Using an extended version of the Asymptotic Bound-state Model (ABM) [1] we predict Feshbach resonances with more promising characteristics than the commonly used resonances in the (|F,mF>) |9/2,-9/2>+|9/2,-7/2> and |9/2,-9/2>+|9/2,-5/2> spin mixtures. We report on an s-wave resonance in the |9/2,-5/2>+|9/2,-3/2> mixture. We have experimentally observed the corresponding loss-feature at B0˜178 G with a width of ˜10G. This resonance is promising due to its large predicted width and the absence of an overlapping p-wave resonance. We present our recent results on measurements of the resonance width and the stability of the system around this and other observed s-wave and p-wave resonances. [4pt] [1] T.G. Tiecke, et al., Phys. Rev. Lett. 104, 053202 (2010).

  6. Efimov Trimers near the Zero-crossing of a Feshbach Resonance

    DEFF Research Database (Denmark)

    Zinner, Nikolaj Thomas

    2012-01-01

    Near a Feshbach resonance, the two-body scattering length can assume any value. When it approaches zero, the next-order term given by the effective range is known to diverge. We consider the question of whether this divergence (and the vanishing of the scattering length) is accompanied by an anom...... by an anomalous solution of the three-boson Schr\\"odinger equation similar to the one found at infinite scattering length by Efimov. Within a simple zero-range model, we find no such solutions, and conclude that higher-order terms do not support Efimov physics.......Near a Feshbach resonance, the two-body scattering length can assume any value. When it approaches zero, the next-order term given by the effective range is known to diverge. We consider the question of whether this divergence (and the vanishing of the scattering length) is accompanied...

  7. Atom-molecule dark states in a Bose-Einstein condensate

    International Nuclear Information System (INIS)

    Winkler, K.; Thalhammer, G.; Theis, M.; Ritsch, H.; Grimm, R.

    2005-01-01

    Full text: We have created a dark quantum superposition state of a Rb Bose-Einstein condensate (BEC) and a degenerate gas of Rb 2 ground state molecules in a specific ro-vibrational state using two-color photoassociation. We infer the presence of this coherent atom-molecule gas from a strong resonant suppression of photoassociation loss. In our experiment the maximal molecule population in the dark state is limited to about 100 Rb 2 molecules due to laser induced decay. The experimental findings can be well described by a simple three mode model. (author)

  8. Trapping and interactions of an ultracold gas of Cs2 molecules

    International Nuclear Information System (INIS)

    Mark, M.; Kraemer, T.; Herbig, J.; Waldburger, P.; Naegerl, H.C.; Chin, C.; Grimm, R.

    2005-01-01

    Full text: We investigate dynamics and interactions of Cs 2 dimers in a CO2-laser dipole trap. Starting with a Bose-Einstein condensate (BEC) of 2.2 x 10 5 Cs atoms, we create ultracold molecules in a single, weakly bound quantum state by sweeping the magnetic field across a narrow Feshbach resonance. When the molecules are created in free space, the conversion efficiency exceeds 30 %, yielding up to 50000 molecules. In our trapping experiments, about 6000 ultracold Cs 2 dimers are prepared in the optical trap at a temperature of 200 nK. We transfer the trapped molecules from the initial molecular state to other molecular states by following avoided crossings. We find two magnetically tunable resonances in collisions between the molecules for one of the molecular states. We interpret these Feshbach-liKEX resonances as being induced by Cs 4 bound states near the molecular scattering continuum. Further, we have discovered a new molecular state with very large orbital angular momentum of l = 8. This state is very weakly coupled to one of the initial molecular states. We use the associated avoided crossing as a molecular beam splitter to realize a molecular Ramsey-type interferometer. Refs. 2 (author)

  9. Canonical quantization of the Bateman-Morse-Feshbach damped oscillator

    International Nuclear Information System (INIS)

    Rideau, G.; Anderson, R.L.; Hebda, P.W.

    1991-01-01

    The Bateman-Morse-Feshbach classical formulation of the damped oscillator is canonically quantized. The spectrum of the Hamiltonian is given. It is shown that the wavefunctions behave asymptotically as a superposition of damped oscillators when their initial values belong to an appropriately-selected dense subset of the Hilbert space. (orig.)

  10. Kohn's theorem in a superfluid Fermi gas with a Feshbach resonance

    International Nuclear Information System (INIS)

    Ohashi, Y.

    2004-01-01

    We investigate the dipole mode in a superfluid gas of Fermi atoms trapped in a harmonic potential. According to Kohn's theorem, the frequency of this collective mode is not affected by an interaction between the atoms and is always equal to the trap frequency. This remarkable property, however, does not necessarily hold in an approximate theory. We explicitly prove that the Hartree-Fock-Bogoliubov generalized random phase approximation (HFB-GRPA), including a coupling between fluctuations in the density and Cooper channels, is consistent with both Kohn's theorem as well as Goldstone's theorem. This proof can be immediately extended to the strong-coupling superfluid theory developed by Nozieres and Schmitt-Rink (NSR), where the effect of superfluid fluctuations is included within the Gaussian level. As a result, the NSR-GRPA formalism can be used to study collective modes in the BCS-BEC crossover region in a manner which is consistent with Kohn's theorem. We also include the effect of a Feshbach resonance and a condensate of the associated molecular bound states. A detailed discussion is given of the unusual nature of the Kohn mode eigenfunctions in a Fermi superfluid, in the presence and absence of a Feshbach resonance. When the molecular bosons feel a different trap frequency from the Fermi atoms, the dipole frequency is shown to depend on the strength of effective interaction associated with the Feshbach resonance

  11. Dark and bright solitons in a Bose-Einstein condensate with a Feshbach resonance

    International Nuclear Information System (INIS)

    Yuce, C; Kilic, A

    2007-01-01

    Both dark and bright solitons are constructed exactly for a Bose-Einstein condensation with a time-dependent scattering length in an expulsive parabolic potential. It is shown analytically how the size of the cloud and the sharp peak of the condensate changes via the Feshbach resonance. It is also found that the atom loss due to three-body recombination can be controlled with the help of Feshbach resonance. The exact calculation is performed to compare the rate of the atom loss between the system with time-dependent scattering length in an expulsive parabolic potential and the system with constant scattering length

  12. Dark and bright solitons in a Bose-Einstein condensate with a Feshbach resonance

    Energy Technology Data Exchange (ETDEWEB)

    Yuce, C; Kilic, A [Department of Physics, Anadolu University, Eskisehir (Turkey)

    2007-02-15

    Both dark and bright solitons are constructed exactly for a Bose-Einstein condensation with a time-dependent scattering length in an expulsive parabolic potential. It is shown analytically how the size of the cloud and the sharp peak of the condensate changes via the Feshbach resonance. It is also found that the atom loss due to three-body recombination can be controlled with the help of Feshbach resonance. The exact calculation is performed to compare the rate of the atom loss between the system with time-dependent scattering length in an expulsive parabolic potential and the system with constant scattering length.

  13. Detecting high-density ultracold molecules using atom–molecule collision

    International Nuclear Information System (INIS)

    Chen, Jun-Ren; Kao, Cheng-Yang; Chen, Hung-Bin; Liu, Yi-Wei

    2013-01-01

    Utilizing single-photon photoassociation, we have achieved ultracold rubidium molecules with a high number density that provides a new efficient approach toward molecular quantum degeneracy. A new detection mechanism for ultracold molecules utilizing inelastic atom–molecule collision is demonstrated. The resonant coupling effect on the formation of the X 1 Σ + g ground state 85 Rb 2 allows for a sufficient number of more deeply bound ultracold molecules, which induced an additional trap loss and heating of the co-existing atoms owing to the inelastic atom–molecule collision. Therefore, after the photoassociation process, the ultracold molecules can be investigated using the absorption image of the ultracold rubidium atoms mixed with the molecules in a crossed optical dipole trap. The existence of the ultracold molecules was then verified, and the amount of accumulated molecules was measured. This method detects the final produced ultracold molecules, and hence is distinct from the conventional trap loss experiment, which is used to study the association resonance. It is composed of measurements of the time evolution of an atomic cloud and a decay model, by which the number density of the ultracold 85 Rb 2 molecules in the optical trap was estimated to be >5.2 × 10 11 cm −3 . (paper)

  14. Alpha-decay within Feshbach theory of nuclear reactions

    International Nuclear Information System (INIS)

    Sandulescu, A.; Silisteanu, I.; Wunsch, R.

    1977-01-01

    In the frame of Feshbach theory of nuclear reactions the alpha-decay widths are determined by the alpha-daughter nucleus optical potential and by the formation factors. It is shown that the calculated absolute values of the alpha widths for Po light isotopes are in good agreement with experimental data, if the real part of the optical potential with the parameters fitted by the low energy α-scattering is used

  15. Spectroscopy of the hghest Rb2 bound states with 10 kHz precision

    NARCIS (Netherlands)

    Verhaar, B.J.; Kokkelmans, S.J.J.M.F.; van Kempen, E.G.M.; Freeland, R.S.; Wynar, R.; Comparat, D.; Ryu, C.; Heinzen, D.J.

    2001-01-01

    We have measured the binding energy of four of the highest bound vibrational levels of the ground electronic states of the ^87Rb2 molecule with a precision better than 10 kHz. The measurements were carried out using stimulated Raman photoassociation in an ^87Rb Bose-Einstein condensate. We have

  16. Integrability of the Gross-Pitaevskii equation with Feshbach resonance management

    International Nuclear Information System (INIS)

    Zhao Dun; Luo Honggang; Chai Huayue

    2008-01-01

    In this Letter we study the integrability of a class of Gross-Pitaevskii equations managed by Feshbach resonance in an expulsive parabolic external potential. By using WTC test, we find a condition under which the Gross-Pitaevskii equation is completely integrable. Under the present model, this integrability condition is completely consistent with that proposed by Serkin, Hasegawa, and Belyaeva [V.N. Serkin, A. Hasegawa, T.L. Belyaeva, Phys. Rev. Lett. 98 (2007) 074102]. Furthermore, this integrability can also be explicitly shown by a transformation, which can convert the Gross-Pitaevskii equation into the well-known standard nonlinear Schroedinger equation. By this transformation, each exact solution of the standard nonlinear Schroedinger equation can be converted into that of the Gross-Pitaevskii equation, which builds a systematical connection between the canonical solitons and the so-called nonautonomous ones. The finding of this transformation has a significant contribution to understanding the essential properties of the nonautonomous solitons and the dynamics of the Bose-Einstein condensates by using the Feshbach resonance technique

  17. Fluorescence of RbH and RbD formed by irradiating the mixed gases Rb + H2 and Rb + D2 with laser light

    International Nuclear Information System (INIS)

    Kato, Hajime; Toyosaka, Yukiko; Suzuki, Tomonari

    1985-01-01

    When a mixture of 85 Rb, 85 Rb 2 , and D 2 was irradiated by laser light at 5145 or 4880 A, small visible particles appeared and the fluorescence spectra were observed. By analyzing these spectra, we determined the rotational constants B v and the centrifugal distortion constants D v and H v for the X 1 Σ + and A 1 Σ + states of 85 RbD. By considering the isotopic dependence of the Dunham coefficients, we determined various molecular constants of 85 RbH whose values were in good agreement with the observed fluorescence spectra of 85 RbH excited by laser lines at 4762, 4765, and 4880 A. The process of RbH formation is discussed. (author)

  18. Studies of inelastic cross-section in Rb(7S) + Rb(5S) collisions

    International Nuclear Information System (INIS)

    Caiyan, L.; Ekers, A.; Latvia Univ., Riga; Klavins, J.; Jansons, M.

    1996-01-01

    The cross section σ = (8 ± 4) x 10 -15 cm 2 was determined for the Rb(7S) + Rb(5S) → Rb(5D) + Rb(5S) excitation energy transfer process, and the quenching cross section σ q = (2 ± 1) x 10 -14 cm 2 for the Rb(5D) state in collisions with ground state Rb atoms. Applying rubidium quasimolecular asymptotic potential curves at relatively large internuclear distances, a qualitative interpretation of the experimental results is presented. It is shown that the quenching of the Rb(5D) atoms in collisions may be explained by a reversed energy pooling process Rb(5D) + Rb(5S) → Rb(5P) + Rb(5P). (orig.)

  19. Single and double charge transfer in Be/sup 4+/+He collisions: A molecular (Feshbach) approach

    International Nuclear Information System (INIS)

    Martin, F.; Riera, A.; Yaez, M.

    1986-01-01

    In recent articles, we pointed out the fundamental difference between the molecular treatment of processes involving a multicharged ion and hydrogen or helium atoms, which is the (formal) autoionizing character of the molecular channels, and we reported a (new) implementation of the Feshbach method to calculate the molecular energies and couplings. In the present work we use the wave functions calculated with this Feshbach method for the BeHe/sup 4+/ quasimolecule, introduce a common translation factor in the formalism, and calculate the single and double charge-exchange cross sections in Be/sup 4+/+He(1s 2 ) collisions for impact energies 0.2--20 keV/amu. The mechanisms of the processes are discussed in detail

  20. Single and double charge transfer in Be/sup 4+/+He collisions: A molecular (Feshbach) approach

    Energy Technology Data Exchange (ETDEWEB)

    Martin, F.; Riera, A.; Yaez, M.

    1986-12-01

    In recent articles, we pointed out the fundamental difference between the molecular treatment of processes involving a multicharged ion and hydrogen or helium atoms, which is the (formal) autoionizing character of the molecular channels, and we reported a (new) implementation of the Feshbach method to calculate the molecular energies and couplings. In the present work we use the wave functions calculated with this Feshbach method for the BeHe/sup 4+/ quasimolecule, introduce a common translation factor in the formalism, and calculate the single and double charge-exchange cross sections in Be/sup 4+/+He(1s/sup 2/) collisions for impact energies 0.2--20 keV/amu. The mechanisms of the processes are discussed in detail.

  1. Semiclassical theory of resonance inelastic electron-molecule collisions

    International Nuclear Information System (INIS)

    Kazanskij, A.K.

    1986-01-01

    Semiclassical approach to the theory of resonance electron-molecule collisions, unlocal with respect to interatomic distance was developed. Two problems were considered: modified adiabatic approach for sigle-pole approximation of R-matrix and Fano-Feshbach-Bardsley theory. It is shown that these problems are similar in semiclassical approximation. A simple equation system with coefficients expressed in quadratures was obtained. It enables to determine amplitudes of all processes (including dissociation adhesion, association ejection, free-free and free-bound transitions) in energetic representation with respect to nucleus vibrations in molecule with allowance for both descrete and continuous spectra of nucleus motion in molecule. Quantitative investigation of the system results to the notion of dynamic energy curve of intermediate state, generalizing the motion of such curve in boomerang theory

  2. Long-Lived Ultracold Molecules with Electric and Magnetic Dipole Moments

    Science.gov (United States)

    Rvachov, Timur M.; Son, Hyungmok; Sommer, Ariel T.; Ebadi, Sepehr; Park, Juliana J.; Zwierlein, Martin W.; Ketterle, Wolfgang; Jamison, Alan O.

    2017-10-01

    We create fermionic dipolar 23Na 6Li molecules in their triplet ground state from an ultracold mixture of 23Na and 6Li. Using magnetoassociation across a narrow Feshbach resonance followed by a two-photon stimulated Raman adiabatic passage to the triplet ground state, we produce 3 ×1 04 ground state molecules in a spin-polarized state. We observe a lifetime of 4.6 s in an isolated molecular sample, approaching the p -wave universal rate limit. Electron spin resonance spectroscopy of the triplet state was used to determine the hyperfine structure of this previously unobserved molecular state.

  3. Fundamental and high-order anapoles in all-dielectric metamaterials via Fano–Feshbach modes competition

    KAUST Repository

    Gongora, J. S. Totero; Favraud, Gael; Fratalocchi, Andrea

    2017-01-01

    by applying a Fano-Feshbach projection scheme, a general technique widely used in the study of quantum mechanical open systems. By expressing the total scattering from the structure in terms of an orthogonal set of internal and external modes, defined

  4. Efficient production of long-lived ultracold Sr2 molecules

    Science.gov (United States)

    Ciamei, Alessio; Bayerle, Alex; Chen, Chun-Chia; Pasquiou, Benjamin; Schreck, Florian

    2017-07-01

    We associate Sr atom pairs on sites of a Mott insulator optically and coherently into weakly bound ground-state molecules, achieving an efficiency above 80%. This efficiency is 2.5 times higher than in our previous work [S. Stellmer, B. Pasquiou, R. Grimm, and F. Schreck, Phys. Rev. Lett. 109, 115302 (2012), 10.1103/PhysRevLett.109.115302] and obtained through two improvements. First, the lifetime of the molecules is increased beyond one minute by using an optical lattice wavelength that is further detuned from molecular transitions. Second, we compensate undesired dynamic light shifts that occur during the stimulated Raman adiabatic passage (STIRAP) used for molecule association. We also characterize and model STIRAP, providing insights into its limitations. Our work shows that significant molecule association efficiencies can be achieved even for atomic species or mixtures that lack Feshbach resonances suitable for magnetoassociation.

  5. Towards 6Li-40K ground state molecules

    International Nuclear Information System (INIS)

    Brachmann, Johannes Felix Simon

    2013-01-01

    The production of a quantum gas with strong long - range dipolar interactions is a major scientific goal in the research field of ultracold gases. In their ro - vibrational ground state Li-K dimers possess a large permanent dipole moment, which could possibly be exploited for the realization of such a quantum gas. A production of these molecules can be achieved by the association of Li and K at a Feshbach resonance, followed by a coherent state transfer. In this thesis, detailed theoretical an experimental preparations to achieve state transfer by means of Stimulated Raman Adiabatic Passage (STIRAP) are described. The theoretical preparations focus on the selection of an electronically excited molecular state that is suitable for STIRAP transfer. In this context, molecular transition dipole moments for both transitions involved in STIRAP transfer are predicted for the first time. This is achieved by the calculation of Franck-Condon factors and a determination of the state in which the 6 Li- 40 K Feshbach molecules are produced. The calculations show that state transfer by use of a single STIRAP sequence is experimentally very well feasible. Further, the optical wavelengths that are needed to address the selected states are calculated. The high accuracy of the data will allow to carry out the molecular spectroscopy in a fast and efficient manner. Further, only a comparatively narrow wavelength tuneability of the spectroscopy lasers is needed. The most suitable Feshbach resonance for the production of 6 Li- 40 K molecules at experimentally manageable magnetic field strengths is occurring at 155 G. Experimentally, this resonance is investigated by means of cross-dimensional relaxation. The application of the technique at various magnetic field strengths in the vicinity of the 155 G Feshbach resonance allows a determination of the resonance position and width with so far unreached precision. This reveals the production of molecules on the atomic side of the resonance

  6. Phase diagrams for an ideal gas mixture of fermionic atoms and bosonic molecules

    DEFF Research Database (Denmark)

    Williams, J. E.; Nygaard, Nicolai; Clark, C. W.

    2004-01-01

    We calculate the phase diagrams for a harmonically trapped ideal gas mixture of fermionic atoms and bosonic molecules in chemical and thermal equilibrium, where the internal energy of the molecules can be adjusted relative to that of the atoms by use of a tunable Feshbach resonance. We plot...... diagrams obtained in recent experiments on the Bose-Einstein condensation to Bardeen-Cooper-Schrieffer crossover, in which the condensate fraction is plotted as a function of the initial temperature of the Fermi gas measured before a sweep of the magnetic field through the resonance region....

  7. Andiamo, a Graphical User Interface for Ohio University's Hauser-Feshbach Implementation

    Science.gov (United States)

    Brooks, Matthew

    2017-09-01

    First and foremost, I am not a physicist. I am an undergraduate computer science major/Japanese minor at Ohio University. However, I am working for Zach Meisel, in the Ohio University's physics department. This is the first software development project I've ever done. My charge is/was to create a graphical program that can be used to more easily set up Hauser-Feshbach equation input files. The input files are of the format expected by the Hauser-Feshbach 2002 code developed by a handful of people at the university. I regularly attend group meetings with Zach and his other subordinates, but these are mostly used as a way for us to discuss our progress and any troubles or roadblocks we may have encountered. I was encouraged to try to come with his group to this event because it could help expose me to the scientific culture of astrophysics research. While I know very little about particles and epic space events, my poster would be an informative and (hopefully) inspiring one that could help get other undergraduates interested in doing object oriented programming. This could be more exposure for them, as I believe a lot of physics majors only learn scripting languages.

  8. Hyperfine structure of 2Σ molecules containing alkaline-earth-metal atoms

    Science.gov (United States)

    Aldegunde, Jesus; Hutson, Jeremy M.

    2018-04-01

    Ultracold molecules with both electron spin and an electric dipole moment offer new possibilities in quantum science. We use density-functional theory to calculate hyperfine coupling constants for a selection of molecules important in this area, including RbSr, LiYb, RbYb, CaF, and SrF. We find substantial hyperfine coupling constants for the fermionic isotopes of the alkaline-earth-metal and Yb atoms. We discuss the hyperfine level patterns and Zeeman splittings expected for these molecules. The results will be important both to experiments aimed at forming ultracold open-shell molecules and to their applications.

  9. Direct fit of spectroscopic data of diatomic molecules by using genetic algorithms: II. The ground state of RbCs

    International Nuclear Information System (INIS)

    Almeida, Marcos M; Prudente, Frederico V; Fellows, Carlos E; Marques, Jorge M C; Pereira, Francisco B

    2011-01-01

    We extend our previous methodology based on genetic algorithms (Marques et al 2008 J. Phys. B: At. Mol. Opt. Phys. 41 085103) to carry out the challenging fit of the RbCs potential curve to spectroscopic data. Specifically, we have fitted an analytic functional form to line positions of the high-resolution Fourier transform spectrum of RbCs obtained by a laser-induced fluorescence technique. The results for the ground electronic state of RbCs show that the present method provides an efficient way to obtain diatomic potentials with great accuracy.

  10. Towards {sup 6}Li-{sup 40}K ground state molecules

    Energy Technology Data Exchange (ETDEWEB)

    Brachmann, Johannes Felix Simon

    2013-02-08

    The production of a quantum gas with strong long - range dipolar interactions is a major scientific goal in the research field of ultracold gases. In their ro - vibrational ground state Li-K dimers possess a large permanent dipole moment, which could possibly be exploited for the realization of such a quantum gas. A production of these molecules can be achieved by the association of Li and K at a Feshbach resonance, followed by a coherent state transfer. In this thesis, detailed theoretical an experimental preparations to achieve state transfer by means of Stimulated Raman Adiabatic Passage (STIRAP) are described. The theoretical preparations focus on the selection of an electronically excited molecular state that is suitable for STIRAP transfer. In this context, molecular transition dipole moments for both transitions involved in STIRAP transfer are predicted for the first time. This is achieved by the calculation of Franck-Condon factors and a determination of the state in which the {sup 6}Li-{sup 40}K Feshbach molecules are produced. The calculations show that state transfer by use of a single STIRAP sequence is experimentally very well feasible. Further, the optical wavelengths that are needed to address the selected states are calculated. The high accuracy of the data will allow to carry out the molecular spectroscopy in a fast and efficient manner. Further, only a comparatively narrow wavelength tuneability of the spectroscopy lasers is needed. The most suitable Feshbach resonance for the production of {sup 6}Li-{sup 40}K molecules at experimentally manageable magnetic field strengths is occurring at 155 G. Experimentally, this resonance is investigated by means of cross-dimensional relaxation. The application of the technique at various magnetic field strengths in the vicinity of the 155 G Feshbach resonance allows a determination of the resonance position and width with so far unreached precision. This reveals the production of molecules on the atomic side

  11. Electronic properties and orbital-filling mechanism in Rb-intercalated copper phthalocyanine

    NARCIS (Netherlands)

    Evangelista, F.; Gotter, R.; Mahne, N.; Nannarone, S.; Ruocco, A.; Rudolf, P.

    2008-01-01

    The evolution of the electronic properties of a thin film of copper phthalocyanine deposited on Al(100) and progressively intercalated with rubidium atoms was followed by photoemission and X-ray absorption spectroscopies. Electron donation from the Rb atoms to the C32H16N8Cu molecules results in the

  12. RB4CD12 epitope expression and heparan sulfate disaccharide composition in brain vasculature.

    Science.gov (United States)

    Hosono-Fukao, Tomomi; Ohtake-Niimi, Shiori; Nishitsuji, Kazuchika; Hossain, Md Motarab; van Kuppevelt, Toin H; Michikawa, Makoto; Uchimura, Kenji

    2011-11-01

    RB4CD12 is a phage display antibody that recognizes a heparan sulfate (HS) glycosaminoglycan epitope. The epitope structure is proposed to contain a trisulfated disaccharide, [-IdoA(2-OSO(3))-GlcNSO(3) (6-OSO(3))-], which supports HS binding to various macromolecules such as growth factors and cytokines in central nervous tissues. Chemically modified heparins that lack the trisulfated disaccharides failed to inhibit the RB4CD12 recognition of HS chains. To determine the localization of the RB4CD12 anti-HS epitope in the brain, we performed an immunohistochemical analysis for cryocut sections of mouse brain. The RB4CD12 staining signals were colocalized with laminin and were detected abundantly in the vascular basement membrane. Bacterial heparinases eliminated the RB4CD12 staining signals. The RB4CD12 epitope localization was confirmed by immunoelectron microscopy. Western blotting analysis revealed that the size of a major RB4CD12-positive molecule is ∼460 kDa in a vessel-enriched fraction of the mouse brain. Disaccharide analysis with reversed-phase ion-pair HPLC showed that [-IdoA(2-OSO(3))-GlcNSO(3) (6-OSO(3))-] trisulfated disaccharide residues are present in HS purified from the vessel-enriched brain fraction. These results indicated that the RB4CD12 anti-HS epitope exists in large quantities in the brain vascular basement membrane. Copyright © 2011 Wiley-Liss, Inc.

  13. Theory of Feshbach molecule formation in a dilute gas during a magnetic field ramp

    DEFF Research Database (Denmark)

    Williams, J. E.; Nygaard, Nicolai; Clark, C. W.

    2006-01-01

    Starting with coupled atom-molecule Boltzmann equations, we develop a simplified model to understand molecule formation observed in recent experiments. Our theory predicts several key features: (1) the effective adiabatic rate constant is proportional to density; (2) in an adiabatic ramp...... show qualitative agreement with the data from [Hodby et al, Phys. Rev. Lett. 94, 120402 (2005)] without the use of adjustable parameters....

  14. Rb-129Xe spin-exchange rates due to binary and three-body collisions at high Xe pressures

    International Nuclear Information System (INIS)

    Cates, G.D.; Fitzgerald, R.J.; Barton, A.S.; Bogorad, P.; Gatzke, M.; Newbury, N.R.; Saam, B.

    1992-01-01

    We have studied the spin relaxation of 129 Xe nuclei due to collisions with Rb atoms at Xe pressures of 245--1817 Torr. Our results can be characterized by two parameters, the Rb- 129 Xe velocity-averaged binary spin-exchange cross section left-angle σv right-angle and a rate γ M that characterizes spin relaxation due to van der Waals molecules. Our results complement earlier studies performed at Xe pressures of about 1 Torr and N 2 pressures of 10--100 Torr. This work is useful for predicting spin-exchange rates between polarized Rb atoms and 129 Xe nuclei

  15. Mobility of Rb{sup +} and Cs{sup +} ions in gases at high pressures; Mobilite des ions Rb{sup +} et Cs{sup +} dans les gaz a haute pression

    Energy Technology Data Exchange (ETDEWEB)

    Bacconnet, E [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    A theoretical study and mobility measurements have been made of Rb{sup +} and Cs{sup +} ions moving in gases at high pressures (10{sup -2} to 25 kg/cm{sup 2}). The theoretical study has been effected using the results of P. Langevin who considers the ions and molecules as elastic spheres and takes into account the electrical polarization forces. The practical work has been carried out using the Rb{sup +} and Cs{sup +} ions emitted by a thermal source; for the measurement of their velocity the method using an ionic beam cut by four grids was employed. Since the source does not work in atmospheres containing oxygen (even in the combined state) the tests only involved pure gases: nitrogen, argon, helium at pressures of from 10{sup -2} to 12 kg/cm{sup 2}. The overall results show that the Rb{sup +} and Cs{sup +} ionic mobilities are very similar and that for fairly-short times spent by the ions in the gas, the measurement results are in agreement with theory. An increase in these times favours a degradation of the ions, which always leads to a decrease in the mobility. This effect is most marked in helium. The gases argon and nitrogen behave identically towards Rb{sup +} and Cs{sup +} ions. (author) [French] Une etude theorique et des mesures de mobilite ont ete effectuees pour des ions Rb{sup +} et Cs{sup +} se deplacant dans des gaz a haute pression (10{sup -2} a 25 kg/cm{sup 2}). L'etude theorique a ete effectuee en utilisant les resultats de P. Langevin qui assimile les ions et les molecules a des spheres elastiques et tient compte des forces de polarisation electrique. L'etude pratique a ete realisee en utilisant des ions Rb{sup +} et Cs{sup +} emis par une source thermique et pour la mesure de leur vitesse, la methode de coupure du faisceau ionique au moyen de quatre grilles a ete adoptee. La source ne fonctionnant pas dans des atmospheres contenant de l'oxygene (meme a l'etat combine) les essais ont seulement porte sur des gaz purs: azote, argon, helium et pour

  16. Efimov states near a Feshbach resonance and the limits of van der Waals universality at finite background scattering length

    Science.gov (United States)

    Langmack, Christian; Schmidt, Richard; Zwerger, Wilhelm

    2018-03-01

    We calculate the spectrum of three-body Efimov bound states near a Feshbach resonance within a model which accounts both for the finite range of interactions and the presence of background scattering. The latter may be due to direct interactions in an open channel or a second overlapping Feshbach resonance. It is found that background scattering gives rise to substantial changes in the trimer spectrum as a function of the detuning away from a Feshbach resonance, in particular in the regime where the background channel supports Efimov states on its own. Compared to the situation with negligible background scattering, the regime where van der Waals universality applies is shifted to larger values of the resonance strength if the background scattering length is positive. For negative background scattering lengths, in turn, van der Waals universality extends to even small values of the resonance strength parameter, consistent with experimental results on Efimov states in 39K. Within a simple model, we show that short-range three-body forces do not affect van der Waals universality significantly. Repulsive three-body forces may, however, explain the observed variation between around -8 and -10 of the ratio between the scattering length where the first Efimov trimer appears and the van der Waals length.

  17. Nuclear-excited Feshbach resonances in the electron scattering from hydrogen halides

    International Nuclear Information System (INIS)

    Knoth, G.; Gote, M.; Radle, M.; Jung, K.; Ehrhardt, H.

    1989-01-01

    The energy dependences of the differential cross sections for the electron impact excitation of the higher vibrational levels (v=2 and v=3) of HF and HCl have been measured. Besides the threshold peak a resonance structure has been observed in the v=3 excitation functions of HF below the cusp structure at the opening of the v=4 channel. This resonance structure is the first experimental proof for the existence of the nuclear-excited Feshbach resonances which are interpreted to be the origin of the threshold peaks in the vibrational excitation channels

  18. PELINSCA, Elastic Scattering and Total Cross-Sections and Polarization by Hauser-Feshbach

    International Nuclear Information System (INIS)

    Engelbrecht, C.A.; Fiedeldey, H.; Tepel, J.W.

    1979-01-01

    1 - Nature of the physical problem solved: Calculates differential and total Cross sections as well as polarization for nuclear elastic scattering of spin 0 or spin 1/2 particles. Calculates Cross sections (differential and total) and decay gamma ray angular correlation for inelastic processes by means of standard Hauser-Feshbach (HF) theory or with modified HF theory including width fluctuation corrections. In elastic scattering optical model parameters may be optimized in a least squares procedure involving experimental measurements. 2 - Method of solution: Schroedinger equation for complex potentials is solved according to Fox-Goodwin method of numerical integration. Coulomb wave functions are calculated by using recurrence relations depending on range of Coulomb and energy parameters. Least squares fits are made using parameter grid and direction of steepest descent. Statistical model calculations are made using closed mathematical expressions. 3 - Restrictions on the complexity of the problem: Elastic scattering calculations limited to spin 0 or spin 1/2 particles. Number of partial waves limited to 51. Statistical model calculations on targets with spin less or equal to 5 and with partial waves up to l=6. Not suitable for heavy-ion Hauser- Feshbach calculations without first removing dimensional limitations. Program handles up to 3 reaction types simultaneously, e.g. (p,p), (p,n) and (p,alpha), each reaction channel having up to 33 final nuclear states

  19. Low-energy positron interactions with atoms and molecules

    International Nuclear Information System (INIS)

    Surko, C M; Gribakin, G F; Buckman, S J

    2005-01-01

    This paper is a review of low-energy positron interactions with atoms and molecules. Processes of interest include elastic scattering, electronic and vibrational excitation, ionization, positronium formation and annihilation. An overview is presented of the currently available theoretical and experimental techniques to study these phenomena, including the use of trap-based positron beam sources to study collision processes with improved energy resolution. State-resolved measurements of electronic and vibrational excitation cross sections and measurement of annihilation rates in atoms and molecules as a function of incident positron energy are discussed. Where data are available, comparisons are made with analogous electron scattering cross sections. Resonance phenomena, common in electron scattering, appear to be less common in positron scattering. Possible exceptions include the sharp onsets of positron-impact electronic and vibrational excitation of selected molecules. Recent energy-resolved studies of positron annihilation in hydrocarbons containing more than a few carbon atoms provide direct evidence that vibrational Feshbach resonances underpin the anomalously large annihilation rates observed for many polyatomic species. We discuss open questions regarding this process in larger molecules, as well as positron annihilation in smaller molecules where the theoretical picture is less clear. (topical review)

  20. RB975242 and RB975201 - Late maturation sugarcane varieties

    Directory of Open Access Journals (Sweden)

    Monalisa Sampaio Carneiro

    2016-11-01

    Full Text Available The sugarcane varieties RB975201 and RB975242 were developed and released for harvest at the end of the season (late maturation in the CentralSouth region of Brazil. In specific environments, these varieties were compared with commercial standards in sugar yield per area. They are resistant to major sugarcane diseases and present the Bru1 gene of resistance to brown rust.

  1. Hauser-Feshbach cross-section calculations for elastic and inelastic scattering of alpha particles-program CORA

    International Nuclear Information System (INIS)

    Hartman, A.; Siemaszko, M.; Zipper, W.

    1975-01-01

    The program CORA was prepared on the basis of Hauser and Feshbach compound reaction formalism. It allows the differential cross-section distributions for the elastic and inelastic scattering of alpha particles (via compound nucleus state) to be calculated. The transmission coefficients are calculated on the basis of a four parameter optical model. The search procedure is also included. (author)

  2. Mobility of Rb{sup +} and Cs{sup +} ions in gases at high pressures; Mobilite des ions Rb{sup +} et Cs{sup +} dans les gaz a haute pression

    Energy Technology Data Exchange (ETDEWEB)

    Bacconnet, E. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    A theoretical study and mobility measurements have been made of Rb{sup +} and Cs{sup +} ions moving in gases at high pressures (10{sup -2} to 25 kg/cm{sup 2}). The theoretical study has been effected using the results of P. Langevin who considers the ions and molecules as elastic spheres and takes into account the electrical polarization forces. The practical work has been carried out using the Rb{sup +} and Cs{sup +} ions emitted by a thermal source; for the measurement of their velocity the method using an ionic beam cut by four grids was employed. Since the source does not work in atmospheres containing oxygen (even in the combined state) the tests only involved pure gases: nitrogen, argon, helium at pressures of from 10{sup -2} to 12 kg/cm{sup 2}. The overall results show that the Rb{sup +} and Cs{sup +} ionic mobilities are very similar and that for fairly-short times spent by the ions in the gas, the measurement results are in agreement with theory. An increase in these times favours a degradation of the ions, which always leads to a decrease in the mobility. This effect is most marked in helium. The gases argon and nitrogen behave identically towards Rb{sup +} and Cs{sup +} ions. (author) [French] Une etude theorique et des mesures de mobilite ont ete effectuees pour des ions Rb{sup +} et Cs{sup +} se deplacant dans des gaz a haute pression (10{sup -2} a 25 kg/cm{sup 2}). L'etude theorique a ete effectuee en utilisant les resultats de P. Langevin qui assimile les ions et les molecules a des spheres elastiques et tient compte des forces de polarisation electrique. L'etude pratique a ete realisee en utilisant des ions Rb{sup +} et Cs{sup +} emis par une source thermique et pour la mesure de leur vitesse, la methode de coupure du faisceau ionique au moyen de quatre grilles a ete adoptee. La source ne fonctionnant pas dans des atmospheres contenant de l'oxygene (meme a l'etat combine) les essais ont seulement porte sur des gaz purs: azote

  3. Prospects for transferring 87Rb84Sr dimers to the rovibrational ground state based on calculated molecular structures

    Science.gov (United States)

    Chen, Tao; Zhu, Shaobing; Li, Xiaolin; Qian, Jun; Wang, Yuzhu

    2014-06-01

    Using fitted model potential curves of the ground and lowest three excited states yielded by the relativistic Kramers-restricted multireference configuration interaction method with 19 electrons correlated, we theoretically investigate the rovibrational properties including the number of vibrational state and diagonally distributed Franck-Condon factors for a 87Rb84Sr molecule. Benefiting from a turning point at about v'=20 for the Franck-Condon factors between the ground state and spin-orbit 2(Ω=1/2) excited state, we choose |2(Ω=1/2),v'=21,J'=1> as the intermediate state in the three-level model to theoretically analyze the possibility of performing stimulated Raman adiabatic passage to transfer weakly bound RbSr molecules to the rovibrational ground state. With 1550 nm pump laser (2 W/cm2) and 1342 nm dump laser (10 mW/cm2) employed and appropriate settings of pulse time length (about 300 μs), we have formalistically achieved a round-trip transfer efficiency of 60%, namely 77% for one-way transfer. The results demonstrate the possibility of producing polar 87Rb84Sr molecules efficiently in a submicrokelvin regime, and further provide promising directions for future theoretical and experimental studies on alkali-alkaline(rare)-earth dimers.

  4. Ultra-cold molecules in an atomic Bose-Einstein condensate

    Science.gov (United States)

    Wynar, Roahn Helden

    2000-08-01

    This thesis is about photoassociation of Bose-condensed 87Rb. Most importantly we report that state selected 87Rb2 molecules were created at rest in a condensate of 87Rb using two-photon photoassociation. Additionally, we have identified three weakly bound states of the 87Rb2 S+u3 , potential for the |1, -1> + |1, - 1> collisional channel. The binding energies of these states are 529.4 +/- .07, 636.0094 +/- .0012, and 24.24 +/- .01 MHz respectively. We have also carried out a detailed study of the density dependence of the shift and width of the two-photon lineshape. This shift and width is modeled using the theory of Bohn and Julienne [34] and in addition to the precise measurement of binding energy we also report the first measurement of an atom molecule scattering length, aam, which we conclude is -180 +/- 150 a0, and the inelastic collision rate, Kinel dependent coherent coupling between atoms and molecules. This theory yields two coupled equations, one for the evolution of atomic condensate amplitude and one for the evolution of molecular condensate amplitude. The nature of the atomic-molecular condensate evolution is shown to depend on six, model parameters including the coherent coupling, given by cn . The other five parameters can be interpreted as light-shifts and incoherent loss rates. We present a calculation intended to estimate the values of these six parameters for the 87Rb - 87Rb 2 system. Based on the results of this calculation we identify two locations in the 87Rb2 spectrum where coherent transfer of population from atomic condensate to molecular condensate is plausible. Finally, we examine the credibility of the theoretical model used to estimate the six parameters used by the mean field theory. By comparing the measured Stark shifts of two-color resonances with predictions based on our theoretical model we conclude that the model is satisfactory for the v = 37 level of the S+u3 potential. This work also describes the experimental details of

  5. Evidence of three-body correlation functions in Rb+ and Sr2+ acetonitrile solutions

    Science.gov (United States)

    D'Angelo, P.; Pavel, N. V.

    1999-09-01

    The local structure of Sr2+ and Rb+ ions in acetonitrile has been investigated by x-ray absorption spectroscopy (XAS) and molecular dynamics simulations. The extended x-ray absorption fine structure above the Sr and Rb K edges has been interpreted in the framework of multiple scattering (MS) formalism and, for the first time, clear evidence of MS contributions has been found in noncomplexing ion solutions. Molecular dynamics has been used to generate the partial pair and triangular distribution functions from which model χ(k) signals have been constructed. The Sr2+ and Rb+ acetonitrile pair distribution functions show very sharp and well-defined first peaks indicating the presence of a well organized first solvation shell. Most of the linear acetonitrile molecules have been found to be distributed like hedgehog spines around the Sr2+ and Rb+ ions. The presence of three-body correlations has been singled out by the existence of well-defined peaks in the triangular configurations. Excellent agreement has been found between the theoretical and experimental data enforcing the reliability of the interatomic potentials used in the simulations. These results demonstrate the ability of the XAS technique in probing the higher-order correlation functions in solution.

  6. Mimicking multi-channel scattering with single-channel approaches

    OpenAIRE

    Grishkevich, Sergey; Schneider, Philipp-Immanuel; Vanne, Yulian V.; Saenz, Alejandro

    2009-01-01

    The collision of two atoms is an intrinsic multi-channel (MC) problem as becomes especially obvious in the presence of Feshbach resonances. Due to its complexity, however, single-channel (SC) approximations, which reproduce the long-range behavior of the open channel, are often applied in calculations. In this work the complete MC problem is solved numerically for the magnetic Feshbach resonances (MFRs) in collisions between generic ultracold 6Li and 87Rb atoms in the ground state and in the ...

  7. Final report on the IAEA research contracts No. 1194/RB, 1194/R1/RB and 1194/R2/RB

    International Nuclear Information System (INIS)

    Zobor, E.; Janosy, J.S.; Szentgali, A.

    1980-09-01

    The final report summarizes the research activities made in the framework of the IAEA Research Contracts No. 1194/RB, 1194/R1/RB and 1194/R2/RB. A multilevel hierarchical control system is treated which uses weakly-coupled low dimensional subsystems under the supervision of a dynamic coordinator program. This self-organizing adaptive control system was checked by a 5 MW research reactor. As an example the paper describes the experimental computer control system of the 5 MW WWR-SM research reactor, where the reactor power and outlet temperature have been controlled on the basis of the treated control concept since 1978. (author)

  8. A full dimensional investigation of infrared spectroscopy of the RbCs dimer using the multi-configuration time-dependent Hartree method

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Huihui; Yang, Yonggang, E-mail: ygyang@sxu.edu.cn; Xiao, Liantuan; Jia, Suotang [State Key Laboratory of Quantum Optics and Quantum Optics Devices, Institute of Laser Spectroscopy, Shanxi University, Taiyuan 030006 (China)

    2013-12-28

    The geometry and infrared absorption spectrum of (RbCs){sub 2} have been studied by full dimensional quantum dynamics simulations. For this purpose, the potential energy and dipole moment surfaces are generated by means of a cluster expansion with all two and three mode correlations, and fitted to analytical expressions with negligible deviations. Accordingly, the ground state (RbCs){sub 2} has a diamond geometry with D{sub 2h} symmetry. The infrared spectrum with frequencies up to 120 cm{sup −1}, exhibits rich details of the fundamentals, overtones, and combination bands; the highest fundamental frequency of (RbCs){sub 2} is only 40.26 cm{sup −1}. The present study unravels important details of the interactions between the widely investigated ultracold RbCs molecules.

  9. Characterization of recombinant B. abortus strain RB51SOD towards understanding the uncorrelated innate and adaptive immune responses induced by RB51SOD compared to its parent vaccine strain RB51

    Directory of Open Access Journals (Sweden)

    Jianguo eZhu

    2011-11-01

    Full Text Available Brucella abortus is a Gram-negative, facultative intracellular pathogen for several mammals, including humans. Live attenuated B. abortus strain RB51 is currently the official vaccine used against bovine brucellosis in the United States and several other countries. Overexpression of protective B. abortus antigen Cu/Zn superoxide dismutase (SOD in a recombinant strain of RB51 (strain RB51SOD significantly increases its vaccine efficacy against virulent B. abortus challenge in a mouse model. An attempt has been made to better understand the mechanism of the enhanced protective immunity of RB51SOD compared to its parent strain RB51. We previously reported that RB51SOD stimulated enhanced Th1 immune response. In this study, we further found that T effector cells derived from RB51SOD-immunized mice exhibited significantly higher cytotoxic T lymphocyte (CTL activity than T effector cells derived from RB51-immunized mice against virulent B. abortus-infected target cells. Meanwhile, the macrophage responses to these two strains were also studied. Compared to RB51, RB51SOD cells had a lower survival rate in macrophages and induced lower levels of macrophage apoptosis and necrosis. The decreased survival of RB51SOD cells correlates with the higher sensitivity of RB51SOD, compared to RB51, to the bactericidal action of either Polymyxin B or sodium dodecyl sulfate (SDS. Furthermore, a physical damage to the outer membrane of RB51SOD was observed by electron microscopy. Possibly due to the physical damage, overexpressed Cu/Zn SOD in RB51SOD was found to be released into the bacterial cell culture medium. Therefore, the stronger adaptive immunity induced by RB51SOD did not correlate with the low level of innate immunity induced by RB51SOD compared to RB51. This unique and apparently contradictory profile is likely associated with the differences in outer membrane integrity and Cu/Zn SOD release.

  10. Dynamics of Rb{sup +}-benzene and Rb{sup +}-benzene-Ar {sub n} (n {<=} 3) clusters

    Energy Technology Data Exchange (ETDEWEB)

    Alberti, M. [Centre de Recerca en Quimica Teorica, Departament de Quimica Fisica, Parc Cientific, Universitat de Barcelona, Marti i Franques, 1, 08028 Barcelona (Spain)], E-mail: m.alberti@ub.edu; Aguilar, A. [Centre de Recerca en Quimica Teorica, Departament de Quimica Fisica, Parc Cientific, Universitat de Barcelona, Marti i Franques, 1, 08028 Barcelona (Spain); Lucas, J.M. [Centre de Recerca en Quimica Teorica, Departament de Quimica Fisica, Parc Cientific, Universitat de Barcelona, Marti i Franques, 1, 08028 Barcelona (Spain); Cappelletti, D. [Dipartimento di Ingegneria Civile ed Ambientale, Universita di Perugia, 06123 Perugia (Italy); Lagana, A. [Dipartimento di Chimica, Universita di Perugia, 06123 Perugia (Italy); Pirani, F. [Dipartimento di Chimica, Universita di Perugia, 06123 Perugia (Italy)

    2006-09-29

    The potential energy function of the Rb{sup +}-benzene cluster and of some of its Ar solvated variants is here modeled using a combination (pairwise sum) of ion(atom)-molecular bond and ion-molecular charges interaction contributions which provide, respectively, the non electrostatic and the electrostatic terms of the total non covalent intermolecular potential energy. In particular, such interaction contributions have been represented using, in addition to the ion(atom) polarizability, the bond polarizability tensor components and the charge distribution which account, respectively, for the polarizability and the quadrupolar moment of the benzene molecule. On the resulting potential energy surface, dynamical calculations have been carried out for the microcanonical ensemble by focusing on isomerization processes and on the effect of the mass of the cation.

  11. First-principles calculations of two cubic fluoropervskite compounds: RbFeF3 and RbNiF3

    International Nuclear Information System (INIS)

    Mubarak, A.A.; Al-Omari, Saleh

    2015-01-01

    We present first-principles calculations of the structural, elastic, electronic, magnetic and optical properties for RbFeF 3 and RbNiF 3 . The full-potential linear augmented plan wave (FP-LAPW) method within the density functional theory was utilized to perform the present calculations. We employed the generalized gradient approximation as exchange-correlation potential. It was found that the calculated analytical lattice parameters agree with previous studies. The analysis of elastic constants showed that the present compounds are elastically stable and anisotropic. Moreover, both compounds are classified as a ductile compound. The calculations of the band structure and density functional theory revealed that the RbFeF 3 compound has a half-metallic behavior while the RbNiF 3 compound has a semiconductor behavior with indirect (M–Γ) band gap. The ferromagnetic behavior was studied for both compounds. The optical properties were calculated for the radiation of up to 40 eV. A beneficial optics technology is predicted as revealed from the optical spectra. - Highlights: • RbFeF 3 and RbNiCl 3 compounds are elastically stable. • RbFeF 3 and RbNiCl 3 compounds are classified as a ductile compound. • The RbFeF 3 compound has a half-metallic behavior while the RbNiF 3 compound has a semiconductor behavior. • The optical properties were calculated for the radiation of up to 40 eV

  12. STAX-2, Neutron Scattering Cross-Sections by Optical Model and Moldauer Theory with Hauser-Feshbach

    International Nuclear Information System (INIS)

    Tomita, Y.

    1972-01-01

    1 - Nature of physical problem solved: The program calculates neutron scattering cross sections by means of the optical model and Moldauer's theory, and can search for potential parameters which reproduce measured cross sections. The Hauser-Feshbach calculation is also possible. 2 - Restrictions on the complexity of the problem: The maximum number of levels is 25. The largest value of the orbital angular momentum is 10

  13. Synthesis and Characterization of the Rubidium Thiophosphate Rb 6 (PS 5 )(P 2 S 10 ) and the Rubidium Silver Thiophosphates Rb 2 AgPS 4 , RbAg 5 (PS 4 ) 2 and Rb 3 Ag 9 (PS 4 ) 4

    KAUST Repository

    Alahmary, Fatimah S.; Davaasuren, Bambar; Khanderi, Jayaprakash; Rothenberger, Alexander

    2016-01-01

    The metal thiophosphates Rb2AgPS4 (2), RbAg5(PS4)2 (3), and Rb3Ag9(PS4)4 (4) were synthesized by stoichiometric reactions, whereas Rb6(PS5)(P2S10) (1) was prepared with excess amount of sulfur. The compounds crystallize as follows: 1 monoclinic, P21

  14. Molecular dissociation and nascent product state distributions detected with atomic wavepacket interferometry and parametric four-wave mixing: Rb2 predissociation observed by quantum beating in Rb at 18.2 THz

    International Nuclear Information System (INIS)

    Xiao, Y; Senin, A A; Ricconi, B J; Kogler, R; Zhu, C J; Eden, J G

    2008-01-01

    Dissociation of a diatomic molecule and the excited-state distribution of the nascent atomic fragments can be detected and characterized by atomic wavepacket interferometry and a coherent nonlinear optical process, such as parametric four-wave mixing (PFWM), in ultrafast pump-probe experiments. Underlying these experiments is a reliance on atom-atom interaction to alter the properties of an atomic wavepacket which, in turn, impacts the phase and amplitude of a coherent optical signal. Specifically, quantum beating in the atomic species provides a sensitive, in situ probe of molecular dissociation by detecting approaching dissociation fragments through long-range dipole-dipole interaction. The resulting influence of this interaction on the amplitude and phase of the quantum beating is observed in temporal or Fourier domains by probing the wavepacket by interferometry and PFWM with 100-150 fs laser pulses. The wavepacket thus serves as a detector of molecular dissociation fragments and the dynamics of atom-atom interactions are converted into the macroscopic domain by the PFWM signal and idler waves. Femtosecond pump-probe experiments are described in which the predissociation of electronically excited Rb 2 states in the ∼24 000-28 000 cm -1 interval, and the distribution of nascent atomic fragments into Rb excited states (7s, 5d, 6s, 4d and 5p) spanning an energy range >1.25 eV, have been observed in Rb vapour with atomic number densities of ∼6 x 10 13 -3 x 10 17 cm -3 . Quantum beating at 18.2 THz (corresponding to the Rb 7s-5d J (J = 5/2) energy defect of ∼608 cm -1 ) is superimposed onto the axially phase matched PFWM signal wave generated at λ S ∼ 420 nm (Rb 6 2 P J → 5 2 S 1/2 transitions) and recovered by Fourier analysis of the signal wave intensity as the pump-probe time delay (Δt) is scanned. The dominant exit channels for Rb 2 predissociation are found to be sensitive to the interval of internuclear separation R in which the molecular

  15. Exploring an ultracold Fermi-Fermi mixture: Interspecies Feshbach resonances and scattering properties of 6Li and 40K

    NARCIS (Netherlands)

    Wille, E.; Spiegelhalder, F.M.; Kerner, G.; Naik, D.; Trenkwalder, A.; Hendl, G.; Schreck, F.; Grimm, R.; Tiecke, T.G.; Walraven, J.T.M.; Kokkelmans, S.J.J.M.F.; Tiesinga, E.; Julienne, P.S.

    2008-01-01

    We report on the observation of Feshbach resonances in an ultracold mixture of two fermionic species, 6Li and 40K. The experimental data are interpreted using a simple asymptotic bound state model and full coupled channels calculations. This unambiguously assigns the observed resonances in terms of

  16. SASSI, Total and Differential Elastic and Inelastic Neutron Cross-Sections by Hauser-Feshbach

    International Nuclear Information System (INIS)

    Benzi, V.; Fabbri, F.; Zuffi, L.

    2001-01-01

    1 - Nature of physical problem solved: Neutron total and differential elastic and inelastic cross-section evaluation by means of the statistical model of Hauser-Feshbach (1) as modified by D. Goldman (2) (3). The Goldman modification includes the effect of spin-orbit coupling on transmission coefficients. 2 - Method of solution: For numerical integration the Fox-Goodwins method is used. 3 - Restrictions on the complexity of the problem: Angular momentum I less than or equal to 50. Number of excited levels less than or equal to 30

  17. International nuclear model code comparison study of Hauser-Feshbach calculations

    International Nuclear Information System (INIS)

    Hodgson, P.E.

    1991-03-01

    The present comparison concerns Hauser-Feshbach calculations with and without the width fluctuation correction. Participants were invited to calculate the elastic and inelastic scattering of neutrons from a fictitious nucleus Co60 (Z=27, N=33) at incident laboratory energies of 0.2, 0.5, 1 and 2 MeV. The optical potential was specified. The differential shape elastic, compound elastic and inelastic cross-sections were tabulated. Among the twenty-five sets of results, twelve were sufficiently consistent with each other to be accepted as benchmark values. These fell into two sets, corresponding to calculations with and without the width fluctuation correction. The differences between the results corresponding to different forms of the width fluctuation correction were less than 2 percent

  18. An adiabatic spectroscopic investigation of the CsRb system in ground and numerous excited states

    Science.gov (United States)

    Souissi, Hanen; Jellali, Soulef; Maha, Chaieb; Habli, Héla; Oujia, Brahim; Gadéa, Florent Xavier

    2017-10-01

    Via ab-initio approximations, we investigate the electronic and structural features of the CsRb molecule. Adiabatic potential energy curves of 261,3Σ+, 181,3Π and 61,3Δ electronic states with their derived spectroscopic constants as well as vibrational levels spacing have been carried out and well explained. Our approach is founded on an Effective Core Potential (ECP) describing the valence electrons of the system. Using a large Gaussian basis set, the full valence Configuration Interaction can be applied easily on the two-effective valence electrons of the CsRb system. Furthermore, a detailed analysis of the electric dipolar properties has been made through the investigation of both permanent and transition dipole moments (PDM and TDM). It is significant that the ionic character connected with electron transfer that is linked to Cs+ Rb- state has been clearly illustrated in the adiabatic permanent dipole moment.

  19. Multichannel modeling and two-photon coherent transfer paths in NaK

    Science.gov (United States)

    Schulze, T. A.; Temelkov, I. I.; Gempel, M. W.; Hartmann, T.; Knöckel, H.; Ospelkaus, S.; Tiemann, E.

    2013-08-01

    We explore possible pathways for the creation of ultracold polar NaK molecules in their absolute electronic and rovibrational ground state starting from ultracold Feshbach molecules. In particular, we present a multichannel analysis of the electronic ground and K(4p)+Na(3s) excited-state manifold of NaK, analyze the spin character of both the Feshbach molecular state and the electronically excited intermediate states and discuss possible coherent two-photon transfer paths from Feshbach molecules to rovibronic ground-state molecules. The theoretical study is complemented by the demonstration of stimulated Raman adiabatic passage from the X1Σ+(v=0) state to the a3Σ+ manifold on a molecular beam experiment.

  20. Studies on the decoupled rotation bands in the nuclei 79Rb, 81Rb, and 79Kr

    International Nuclear Information System (INIS)

    Panqueva Alvarez, J.H.

    1982-01-01

    High spin states in 79 Rb, 81 Rb, and 79 Kr were studied by means of the following reactions: 63 Cu( 19 F,p2n) 79 Rb, 70 Ge( 12 C,p2n) 79 Rb, 65 Cu( 16 O,2n) 79 Rb, 65 Cu( 19 F,p2n) 81 Rb, 63 Cu( 19 F,2pn) 79 Kr, and 70 Ge( 12 C,2pn) 79 Kr. On the base of γ single spectra, excitation functions, γ angular distributions, γγ and nγ coincidences, RDDS- and DSA lifetime measurements a level scheme of 79 Rb with 13 new found excited states is proposed. Also a series of stretched E2-transitions between posivite parity states in 79 Kr could be identified. The observed M1 and E2 transition probabilities, which were obtained via the experimental determination of the lifetime as well the branching ratio of 26 excited states, form the base for a comprehensive discussion of the nuclear structure of the studied isotopes. For this reason theoretical calculations with the asymmetric rotor-plus-quasiparticle with variable moment of inertia (AROVMI) as well with the interacting boson-fermion (IBVM) model were performed. The good agreement between experiment and theory permits to relate the decrease of the B(E2)-values in 79 Rb to a finite dimensional (N=8) boson space, to cancel the discrepancies stated by Friederichs et.al., and to analyze 79 Kr the influence of a gsub(9/2) neutron on the deformation of the 78 Kr core. (orig./HSI) [de

  1. Multichannel coupling with supersymmetric quantum mechanics and exactly-solvable model for the Feshbach resonance

    International Nuclear Information System (INIS)

    Sparenberg, Jean-Marc; Samsonov, Boris F; Foucart, Francois; Baye, Daniel

    2006-01-01

    A new type of supersymmetric transformations of the coupled-channel radial Schroedinger equation is introduced, which do not conserve the vanishing behaviour of solutions at the origin. Contrary to the usual transformations, these 'non-conservative' transformations allow, in the presence of thresholds, the construction of well-behaved potentials with coupled scattering matrices from uncoupled potentials. As an example, an exactly-solvable potential matrix is obtained which provides a very simple model of the Feshbach-resonance phenomenon. (letter to the editor)

  2. Stability condition of a strongly interacting boson-fermion mixture across an interspecies Feshbach resonance

    International Nuclear Information System (INIS)

    Yu Zengqiang; Zhai Hui; Zhang Shizhong

    2011-01-01

    We study the properties of dilute bosons immersed in a single-component Fermi sea across a broad boson-fermion Feshbach resonance. The stability of the mixture requires that the bare interaction between bosons exceeds a critical value, which is a universal function of the boson-fermion scattering length, and exhibits a maximum in the unitary region. We calculate the quantum depletion, momentum distribution, and the boson contact parameter across the resonance. The transition from condensate to molecular Fermi gas is also discussed.

  3. On the chemical resolution of the {sup 87}Rb{sup +} (s{sup 0})/{sup 87}Sr{sup +} (s{sup 1}) isobaric interference: A kinetic search for an optimum reagent

    Energy Technology Data Exchange (ETDEWEB)

    Cheng Ping; Koyanagi, Gregory K. [Department of Chemistry, Centre for Research in Mass Spectrometry and Centre for Research in Earth and Space Science, York University, Toronto, Ontario, M3J 1P3 (Canada); Bohme, Diethard K. [Department of Chemistry, Centre for Research in Mass Spectrometry and Centre for Research in Earth and Space Science, York University, Toronto, Ontario, M3J 1P3 (Canada)], E-mail: dkbohme@yorku.ca

    2008-10-03

    Room-temperature reactions of the atomic cations Sr{sup +} and Rb{sup +} have been surveyed systematically with a variety of gases using an Inductively-Coupled Plasma/Selected-Ion Flow Tube (ICP/SIFT) tandem mass spectrometer. Rate coefficients and product distributions have been measured in He buffer gas at 0.35 Torr and 295 K for reactions of Sr{sup +} and Rb{sup +} with CH{sub 3}F, CH{sub 3}Cl, N{sub 2}O, CO{sub 2}, CS{sub 2}, SF{sub 6}, D{sub 2}O and NH{sub 3}. Rb{sup +} (s{sup 0}) is seen to be quite inert with these molecules and reacts either slowly by molecule addition or not at all, while Sr{sup +} (s{sup 1}) is much more reactive with all these 8 molecules, especially with CH{sub 3}F, CH{sub 3}Cl, N{sub 2}O and SF{sub 6}. Sr{sup +} reacts with CH{sub 3}F and SF{sub 6} by F-atom transfer, with CH{sub 3}Cl by Cl-atom transfer and with N{sub 2}O by O-atom transfer, and the reaction rate coefficients are all quite high, k {>=} 1.4 x 10{sup -11} cm{sup 3} molecules{sup -1} s{sup -1}. The extreme differences in reactivity with CH{sub 3}F, SF{sub 6}, CH{sub 3}Cl and N{sub 2}O provide a chemical basis for the separation of isobaric interferences of {sup 87}Rb{sup +} and {sup 87}Sr{sup +} often encountered in ICP-MS. Among these four molecules, SF{sub 6} exhibits the largest difference in reactivity, almost a factor of 10{sup 4}, and so is identified as the kinetically recommended reagent for the chemical resolution of the isobaric interference of {sup 87}Rb{sup +} and {sup 87}Sr{sup +}.

  4. Controlling interactions between highly magnetic atoms with Feshbach resonances.

    Science.gov (United States)

    Kotochigova, Svetlana

    2014-09-01

    This paper reviews current experimental and theoretical progress in the study of dipolar quantum gases of ground and meta-stable atoms with a large magnetic moment. We emphasize the anisotropic nature of Feshbach resonances due to coupling to fast-rotating resonant molecular states in ultracold s-wave collisions between magnetic atoms in external magnetic fields. The dramatic differences in the distribution of resonances of magnetic (7)S3 chromium and magnetic lanthanide atoms with a submerged 4f shell and non-zero electron angular momentum is analyzed. We focus on dysprosium and erbium as important experimental advances have been recently made to cool and create quantum-degenerate gases for these atoms. Finally, we describe progress in locating resonances in collisions of meta-stable magnetic atoms in electronic P-states with ground-state atoms, where an interplay between collisional anisotropies and spin-orbit coupling exists.

  5. Calibration of RB reactor power; Kalibrisanje snage reaktora RB

    Energy Technology Data Exchange (ETDEWEB)

    Sotic, O; Markovic, H; Ninkovic, M; Strugar, P; Dimitrijevic, Z; Takac, S; Stefanovic, D; Kocic, A; Vranic, S [Boris Kidric Institute of Nuclear Sciences Vinca, Beograd (Yugoslavia)

    1976-09-15

    The first and only calibration of RB reactor power was done in 1962, and the obtained calibration ratio was used irrespective of the lattice pitch and core configuration. Since the RB reactor is being prepared for operation at higher power levels it was indispensable to reexamine the calibration ratio, estimate its dependence on the lattice pitch, critical level of heavy water and thickness of the side reflector. It was necessary to verify the reliability of control and dosimetry instruments, and establish neutron and gamma dose dependence on reactor power. Two series of experiments were done in June 1976. First series was devoted to tests of control and dosimetry instrumentation and measurements of radiation in the RB reactor building dependent on reactor power. Second series covered measurement of thermal and epithermal neuron fluxes in the reactor core and calculation of reactor power. Four different reactor cores were chosen for these experiments. Reactor pitches were 8, 8{radical}2, and 16 cm with 40, 52 and 82 fuel channels containing 2% enriched fuel. Obtained results and analysis of these results are presented in this document with conclusions related to reactor safe operation.

  6. Control of the dynamics of coupled atomic-molecular Bose-Einstein condensates: Modified Gross-Pitaevskii approach

    International Nuclear Information System (INIS)

    Gupta, Moumita; Dastidar, Krishna Rai

    2009-01-01

    We study the dynamics of the atomic and molecular Bose-Einstein condensates (BECs) of 87 Rb in a spherically symmetric trap coupled by stimulated Raman photoassociation process. Considering the higher order nonlinearity in the atom-atom interaction we analyze the dynamics of the system using coupled modified Gross-Pitaevskii (MGP) equations and compare it with mean-field coupled Gross-Pitaevskii (GP) dynamics. Considerable differences in the dynamics are obtained in these two approaches at large scattering length, i.e., for large values of peak-gas parameter x pk ≥10 -3 . We show how the dynamics of the coupled system is affected when the atom-molecule and molecule-molecule interactions are considered together with the atom-atom interaction and also when the strengths of these three interactions are increased. The effect of detuning on the efficiency of conversion of atomic fractions into molecules is demonstrated and the feasibility of maximum molecular BEC formation by varying the Raman detuning parameter at different values of time is explored. Thus by varying the Raman detuning and the scattering length for atom-atom interaction one can control the dynamics of the coupled atomic-molecular BEC system. We have also solved coupled Gross-Pitaevskii equations for atomic to molecular condensate formation through magnetic Feshbach resonance in a BEC of 85 Rb. We found similar features for oscillations between atomic and molecular condensates noted in previous theoretical study and obtained fairly good agreement with the evolution of total atomic condensate observed experimentally.

  7. Analysis list: RB1 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available RB1 Prostate,Uterus + hg19 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/R...B1.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/RB1.5.tsv http://dbarchive.biosciencedbc.jp/...kyushu-u/hg19/target/RB1.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/RB1.Prostate.tsv,http://dbarchive.bioscience...dbc.jp/kyushu-u/hg19/colo/RB1.Uterus.tsv http://dbarchive.bioscience...dbc.jp/kyushu-u/hg19/colo/Prostate.gml,http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/Uterus.gml ...

  8. Feshbach-Kerman-Koonin analysis of 93Nb reactions: P→Q transitions and reduced importance of multistep compound emission

    International Nuclear Information System (INIS)

    Chadwick, M.B.; Young, P.G.

    1993-01-01

    We have implemented multistep compound (MSC) and multistep direct (MSD) preequilibrium theories of Feshbach, Kerman, and Koonin (FKK) for the calculation of nucleon-induced reactions. Unlike most previous analyses, which have concentrated on just one of these multistep mechanisms, we consider both mechanisms as well as subsequent Hauser-Feshbach equilibrium emission, and describe the complete nucleon emission spectra and angular distributions quantum mechanically. We compare theoretical calculations of (n,n') and (n,p) reactions on 93 Nb at energies of 14, 20, and 25.7 MeV with experimental data. Our analysis suggests that the FKK theory should be modified to allow transitions from the MSD to MSC preequilibrium chains, and shows MSC processes to be less important than previously thought. We find that the MSD mechanism dominates preequilibrium emission even for incident neutron energies as low as 14 MeV. A model to account for preequilibrium flux cascading from the MSD to MSC chain is presented, and we check its validity with a least-squares fit to data which establishes the experimentally observed partitioning between MSD and MSC

  9. Phase diagram of a polarized Fermi gas across a Feshbach resonance in a potential trap

    International Nuclear Information System (INIS)

    Yi, W.; Duan, L.-M.

    2006-01-01

    We map out the detailed phase diagram of a trapped ultracold Fermi gas with population imbalance across a wide Feshbach resonance. We show that under the local density approximation, the properties of the atoms in any (anisotropic) harmonic traps are universally characterized by three dimensionless parameters: the normalized temperature, the dimensionless interaction strength, and the population imbalance. We then discuss the possible quantum phases in the trap, and quantitatively characterize their phase boundaries in various typical parameter regions

  10. Regulations and instructions for RB reactor operation; Propisi i uputstva za rad reaktora RB

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1977-07-01

    This document includes regulations for reactor RB operation, behaviour and presence of staff in the reactor building; regulations for performing experiments at the RB reactor, regulations and int ructions for the reactor operators and other staff on duty. A chapter is devoted to instruction for reactor operation with the operating documentation and special duties of the operators. Regulations and instruction concerned with accidents are described with classification of accidents and evacuation plan. Annexes to this document include: the present status of the reactor; program for training the reactor operators; forms which are obligatory to be signed for any operating activity, and the certificate of the RB reactor lattice.

  11. Ground state of the polar alkali-metal-atom-strontium molecules: Potential energy curve and permanent dipole moment

    International Nuclear Information System (INIS)

    Guerout, R.; Aymar, M.; Dulieu, O.

    2010-01-01

    In this study, we investigate the structure of the polar alkali-metal-atom-strontium diatomic molecules as possible candidates for the realization of samples of ultracold polar molecular species not yet investigated experimentally. Using a quantum chemistry approach based on effective core potentials and core polarization potentials, we model these systems as effective three-valence-electron systems, allowing for calculation of electronic properties with full configuration interaction. The potential curve and the permanent dipole moment of the 2 Σ + ground state are determined as functions of the internuclear distance for LiSr, NaSr, KSr, RbSr, and CsSr molecules. These molecules are found to exhibit a significant permanent dipole moment, though smaller than those of the alkali-metal-atom-Rb molecules.

  12. Cold Rydberg molecules

    Science.gov (United States)

    Raithel, Georg; Zhao, Jianming

    2017-04-01

    Cold atomic systems have opened new frontiers at the interface of atomic and molecular physics. These include research on novel types of Rydberg molecules. Three types of molecules will be reviewed. Long-range, homonuclear Rydberg molecules, first predicted in [1] and observed in [2], are formed via low-energy electron scattering of the Rydberg electron from a ground-state atom within the Rydberg atom's volume. The binding mostly arises from S- and P-wave triplet scattering. We use a Fermi model that includes S-wave and P-wave singlet and triplet scattering, the fine structure coupling of the Rydberg atom and the hyperfine structure coupling of the 5S1/2 atom (in rubidium [3]). The hyperfine structure gives rise to mixed singlet-triplet potentials for both low-L and high-L Rydberg molecules [3]. A classification into Hund's cases [3, 4, 5] will be discussed. The talk further includes results on adiabatic potentials and adiabatic states of Rydberg-Rydberg molecules in Rb and Cs. These molecules, which have even larger bonding length than Rydberg-ground molecules, are formed via electrostatic multipole interactions. The leading interaction term of neutral Rydberg-Rydberg molecules is between two dipoles, while for ionic Rydberg molecules it is between a dipole and a monopole. NSF (PHY-1506093), NNSF of China (61475123).

  13. Theoretical model for ultracold molecule formation via adaptive feedback control

    OpenAIRE

    Poschinger, Ulrich; Salzmann, Wenzel; Wester, Roland; Weidemueller, Matthias; Koch, Christiane P.; Kosloff, Ronnie

    2006-01-01

    We investigate pump-dump photoassociation of ultracold molecules with amplitude- and phase-modulated femtosecond laser pulses. For this purpose a perturbative model for the light-matter interaction is developed and combined with a genetic algorithm for adaptive feedback control of the laser pulse shapes. The model is applied to the formation of 85Rb2 molecules in a magneto-optical trap. We find for optimized pulse shapes an improvement for the formation of ground state molecules by more than ...

  14. RB Research nuclear reactor RB reactor, Annual report for 2000

    International Nuclear Information System (INIS)

    Milosevic, M.

    2000-12-01

    Report on RB reactor operation during 2000 contains 3 parts. Part one contains a brief description of reactor operation and reactor components, relevant dosimetry data and radiation protection issues, personnel and financial data. Part two is devoted to maintenance of the reactor components, namely, fuel, heavy water, reactor vessel, heavy water circulation system, absorption rods and heavy water level-meters, maintenance of electronic, mechanical, electrical and auxiliary equipment. Part three contains data concerned with reactor operation and utilization with a comprehensive list of publications resulting from experiments done at the RB reactor. It contains data about reactor operation during previous 14 years, i.e. from 1986 - 2000

  15. Conversion of a Degenerate Fermi Gas of 6Li Atoms to a Molecular BEC

    International Nuclear Information System (INIS)

    Strecker, K.E.; Partridge, G.B.; Kamar, R.I.; Jack, M.W.; Hulet, R.G.

    2005-01-01

    Atomic Feshbach resonances have recently been used to produce a strongly interacting Fermi gas, where the BCS/BEC crossover can be explored. We have used both narrow and broad Feshbach resonances to convert a quantum degenerate Fermi gas of 6Li atoms into an ultracold gas of Li2 molecules. For the narrow resonances, the molecules are formed by coherent adiabatic passage through the resonance. We find that 50% of the atoms are converted to molecules. Furthermore, the lifetime of these molecules was measured to be surprisingly long, 1 s. We will discuss these measurements in the context of the present theoretical understanding. Molecules can also be formed using static fields near the broad Feshbach resonance. The lifetime of these molecules is again long, and sufficient to enable their evaporation to a Bose-Einstein condensate. Phase contrast images of the molecular condensate are presented. The BCS/BEC crossover may be explored by starting with a pure molecular condensate on the low-field side of the Feshbach resonance, and adiabatically changing the field to any final value around resonance. We combine this ability with optical spectroscopy on a bound-bound molecular transition to probe the nature of the many-body wavefunction in the crossover regime

  16. Half-life measurement of 89Rb

    International Nuclear Information System (INIS)

    Guo Xiaoqing; Yuan Daqing; Xu Lijun; Chen Kesheng; Wu Yongle; Zheng Yanming; Yao Shunhe

    2013-01-01

    89 Rb is an important fission product used for monitoring possible release of fission products from fuel element. The half-life is one of important nuclear parameters. The half-life of 89 Rb was determined using reference source method with two sets of HPGe detectors by place-relay way. In reference source method, the ratio of net full- energy peak areas from the measure nuclide and the reference source was used to avoid the count correction caused by dead time and pileup. For the very short half-life of 89 Rb, the half-life iterative method was used in data analysis and the translation method was used in data unification. Finally, the measured half-life of 89 Rb is (14.41±0.04) min. (authors)

  17. 82Sr--82Rb radioisotope generator

    International Nuclear Information System (INIS)

    Grant, P.M.; Erdal, B.R.; O'Brien, H.A.

    1976-01-01

    An improved 82 Sr- 82 Rb radioisotope generator system, based upon the complexing ion exchange resin Chelex-100, has been developed. Columns of this material can be easily and rapidly milked, and the Rb-Sr separation factor for a fresh generator was found to be greater than 10 7 . Approximately 80 percent of the 82 Rb present was delivered in a 15-ml volume of aqueous 0.2 M NH 4 Cl solution. After more than 6 liters of eluant had been put through the generator, the Rb-Sr separation factor was still observed to be greater than 10 5 , and no unusual strontium breakthrough behavior was seen in the system over nearly three 82 Sr half lives. 2 claims, no drawings

  18. RV Ronald H. Brown Cruise RB1201 (EM122)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Cruise RB1201 was led by Chief Scientist Molly Baringer (AOML, NOAA, Miami) as per previous cruises RB0602, RB0701 and RB0901. The three main objectives were:...

  19. Production, quality control and initial imaging studies of [82mRb]RbCl for PET studies

    International Nuclear Information System (INIS)

    Rowshanfarzad, P.; Jalilian, A.R.; Kiyomarsi, M.; Sabet, M.; Karimian, A.R.; Moradkhani, S.; Mirzaii, M.

    2006-01-01

    Rubidium-82m was prepared via 15.4 MeV proton irradiation of a krypton-82 gaseous target (30% enrichment). Washing the target chamber with hot water yielded a Rb-82m containing solution, which was further purified using short column chromatography in order to remove organic/inorganic impurities. The flowthrough was formulated in normal saline for injection. Radionuclide, radiochemical and chemical purity tests were performed prior to administration to rats for imaging (radiochemical yield: 95-97%, radiochemical purity > 97%). Preliminary dual-head coincidence studies were performed to determine the distribution of [ 82m Rb]Rb in normal rats. For biodistribution studies, Rb-81 was injected to rats and tracer accumulation in heart, GI and bladder was determined after sacrification in time intervals. A yield of 1.3 GBq at EOB, 235.7 MBq/μAh was obtained. (authors)

  20. Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma

    Science.gov (United States)

    2013-01-01

    Background Alveolar rhabdomyosarcoma (aRMS) is a myogenic childhood sarcoma frequently associated with a translocation-mediated fusion gene, Pax3:Foxo1a. Methods We investigated the complementary role of Rb1 loss in aRMS tumor initiation and progression using conditional mouse models. Results Rb1 loss was not a necessary and sufficient mutational event for rhabdomyosarcomagenesis, nor a strong cooperative initiating mutation. Instead, Rb1 loss was a modifier of progression and increased anaplasia and pleomorphism. Whereas Pax3:Foxo1a expression was unaltered, biomarkers of aRMS versus embryonal rhabdomyosarcoma were both increased, questioning whether these diagnostic markers are reliable in the context of Rb1 loss. Genome-wide gene expression in Pax3:Foxo1a,Rb1 tumors more closely approximated aRMS than embryonal rhabdomyosarcoma. Intrinsic loss of pRb function in aRMS was evidenced by insensitivity to a Cdk4/6 inhibitor regardless of whether Rb1 was intact or null. This loss of function could be attributed to low baseline Rb1, pRb and phospho-pRb expression in aRMS tumors for which the Rb1 locus was intact. Pax3:Foxo1a RNA interference did not increase pRb or improve Cdk inhibitor sensitivity. Human aRMS shared the feature of low and/or heterogeneous tumor cell pRb expression. Conclusions Rb1 loss from an already low pRb baseline is a significant disease modifier, raising the possibility that some cases of pleomorphic rhabdomyosarcoma may in fact be Pax3:Foxo1a-expressing aRMS with Rb1 or pRb loss of function. PMID:24274149

  1. Continuous all-optical deceleration of molecular beams and demonstration with Rb atoms

    Science.gov (United States)

    Long, Xueping; Jayich, Andrew; Campbell, Wesley

    2017-04-01

    Ultracold samples of molecules are desirable for a variety of applications, such as many-body physics, precision measurement and quantum information science. However, the pursuit of ultracold molecules has achieved limited success: spontaneous emission into many different dark states makes it hard to optically decelerate molecules to trappable speed. We propose to address this problem with a general optical deceleration technique that exploits a pump-dump pulse pair from a mode-locked laser. A molecular beam is first excited by a counter-propagating ``pump'' pulse. The molecular beam is then driven back to the initial ground state by a co-propagating ``dump'' pulse via stimulated emission. The delay between the pump and dump pulse is set to be shorter than the excited state lifetimes in order to limit decays to dark states. We report progress benchmarking this stimulated force by accelerating a cold sample of neutral Rb atoms.

  2. Resonance reactions and enhancement of weak interactions in collisions of cold molecules

    International Nuclear Information System (INIS)

    Flambaum, V. V.; Ginges, J. S. M.

    2006-01-01

    With the creation of ultracold atoms and molecules, a new type of chemistry - 'resonance' chemistry - emerges: chemical reactions can occur when the energy of colliding atoms and molecules matches a bound state of the combined molecule (Feshbach resonance). This chemistry is rather similar to reactions that take place in nuclei at low energies. In this paper we suggest some problems for future experimental and theoretical work related to the resonance chemistry of ultracold molecules. Molecular Bose-Einstein condensates are particularly interesting because in this system collisions and chemical reactions are extremely sensitive to weak fields; also, a preferred reaction channel may be enhanced due to a finite number of final states. The sensitivity to weak fields arises due to the high density of narrow compound resonances and the macroscopic number of molecules with kinetic energy E=0 (in the ground state of a mean-field potential). The high sensitivity to the magnetic field may be used to measure the distribution of energy intervals, widths, and magnetic moments of compound resonances and study the onset of quantum chaos. A difference in the production rate of right-handed and left-handed chiral molecules may be produced by external electric E and magnetic B fields and the finite width Γ of the resonance (correlation ΓE·B). The same effect may be produced by the parity-violating energy difference in chiral molecules

  3. Theoretical study on the ground state of the polar alkali-metal-barium molecules: Potential energy curve and permanent dipole moment

    International Nuclear Information System (INIS)

    Gou, Dezhi; Kuang, Xiaoyu; Gao, Yufeng; Huo, Dongming

    2015-01-01

    In this paper, we systematically investigate the electronic structure for the 2 Σ + ground state of the polar alkali-metal-alkaline-earth-metal molecules BaAlk (Alk = Li, Na, K, Rb, and Cs). Potential energy curves and permanent dipole moments (PDMs) are determined using power quantum chemistry complete active space self-consistent field and multi-reference configuration interaction methods. Basic spectroscopic constants are derived from ro-vibrational bound state calculation. From the calculations, it is shown that BaK, BaRb, and BaCs molecules have moderate values of PDM at the equilibrium bond distance (BaK:1.62 D, BaRb:3.32 D, and BaCs:4.02 D). Besides, the equilibrium bond length (4.93 Å and 5.19 Å) and dissociation energy (0.1825 eV and 0.1817 eV) for the BaRb and BaCs are also obtained

  4. Synthesis and characterization of the superonic-based secondary battery cell Ag/RbAg4I5/RbI3

    International Nuclear Information System (INIS)

    Effendi Nurdin; Jahja, A.K.; Purnama, S.

    2000-01-01

    The solid electrolyte material silver based, RbAg 4 I 5 had been used as electrolyte in making a secondary rechargeable battery cell with silver (Ag) as the anode and rubidium tri-iodide (RbI 3 ) as the cathode.The charge-discharge characteristics measurements and the battery polarization in normal atmospheric pressure, at ambient temperature had been carried out. It can be deduced that the cell configuration Ag/RbAg 4I5/ RbI 3 has performed as a secondary battery. The cell performed well with current density up to 230 μA/cm 2

  5. Production of 83Rb and development of a generator for the separation of sup(83m)Kr from 83Rb

    International Nuclear Information System (INIS)

    Krueger, A.; Lieser, K.H.

    1975-01-01

    83 Rb was produced from rubidium by a (γ,2n)-reaction. The specific activity in the irradiated samples of RbCl was 0.2 to 0.3mCi 83 Rb/gRb. For the separation of the sup(83m)Kr in the liquid phase the cation exchanger Dowex-50WX12 proved to be a suitable carrier. sup(83m)Kr was eluted by bidistilled water. The yield ranged from 85-95%, at an elution time of 3 minutes. The decontamination factor was > 10 6 . The separation of sup(83m)Kr in the gaseous phase was effected by floating a 83 Rb loaded column with an elution gas. The best results were obtained with a generator containing aluminium oxide as carrier for 83 Rb. The yield of sup(83m)Kr was 90-100%, the decontamination factor > 10 4 , the time needed for the separation 20-60 seconds. All generators proved to be very safe even after long time of use. (orig.) [de

  6. Three-Body Recombination near a Narrow Feshbach Resonance in Li 6

    Science.gov (United States)

    Li, Jiaming; Liu, Ji; Luo, Le; Gao, Bo

    2018-05-01

    We experimentally measure and theoretically analyze the three-atom recombination rate, L3, around a narrow s -wave magnetic Feshbach resonance of Li 6 - Li 6 at 543.3 G. By examining both the magnetic field dependence and, especially, the temperature dependence of L3 over a wide range of temperatures from a few μ K to above 200 μ K , we show that three-atom recombination through a narrow resonance follows a universal behavior determined by the long-range van der Waals potential and can be described by a set of rate equations in which three-body recombination proceeds via successive pairwise interactions. We expect the underlying physical picture to be applicable not only to narrow s wave resonances, but also to resonances in nonzero partial waves, and not only at ultracold temperatures, but also at much higher temperatures.

  7. Relationship between Feshbach's and Green's function theories of the nucleon-nucleus mean field

    International Nuclear Information System (INIS)

    Capuzzi, F.; Mahaux, C.

    1995-01-01

    We clarify the relationship and difference between theories of the optical-model potential which had previously been developed in the framework of Feshbach's projection operator approach to nuclear reactions and of Green's function theory, respectively. For definiteness, we consider the nucleon-nucleus system but all results can readily be adapted to the atomic case. The effects of antisymmetrization are properly taken into account. It is shown that one can develop along closely parallel lines the theories of open-quotes holeclose quotes and open-quotes particleclose quotes mean fields. The open-quotes holeclose quotes one-body Hamiltonians describe the single-particle properties of the system formed when one nucleon is taken away from the target ground state, for instance in knockout of pickup processes. The particle one-body Hamiltonians are associated with the system formed when one nucleon is elastically scattered from the ground state, or is added to it by means of stripping reactions. An infinite number of particle, as well as of hole, Hamiltonians are constructed which all yield exactly the same single-particle wave functions. Many open-quotes equivalentclose quotes one-body Hamiltonians can coexist because these operators have a complicated structure: they are nonlocal, complex, and energy-dependent. They do not have the same analytic properties in the complex energy plane. Their real and imaginary parts fulfill dispersion relations which may be different. It is shown that hole and particle Hamiltonians can also be constructed by decomposing any vector of the Hilbert space into two parts which are not orthogonal to one another, in contrast to Feshbach's original theory; one interest of this procedure is that the construction and properties of the corresponding hole Hamiltonian can be justified in a mathematically rigorous way. We exhibit the relationship between the hole and particle Hamiltonians and the open-quotes mass operator.close quotes

  8. Differential gene expression profiling of endometrium during the mid-luteal phase of the estrous cycle between a repeat breeder (RB) and non-RB cows.

    Science.gov (United States)

    Hayashi, Ken-Go; Hosoe, Misa; Kizaki, Keiichiro; Fujii, Shiori; Kanahara, Hiroko; Takahashi, Toru; Sakumoto, Ryosuke

    2017-03-23

    Repeat breeding directly affects reproductive efficiency in cattle due to an increase in services per conception and calving interval. This study aimed to investigate whether changes in endometrial gene expression profile are involved in repeat breeding in cows. Differential gene expression profiles of the endometrium were investigated during the mid-luteal phase of the estrous cycle between repeat breeder (RB) and non-RB cows using microarray analysis. The caruncular (CAR) and intercaruncular (ICAR) endometrium of both ipsilateral and contralateral uterine horns to the corpus luteum were collected from RB (inseminated at least three times but not pregnant) and non-RB cows on Day 15 of the estrous cycle (4 cows/group). Global gene expression profiles of these endometrial samples were analyzed with a 15 K custom-made oligo-microarray for cattle. Immunohistochemistry was performed to investigate the cellular localization of proteins of three identified transcripts in the endometrium. Microarray analysis revealed that 405 and 397 genes were differentially expressed in the CAR and ICAR of the ipsilateral uterine horn of RB, respectively when compared with non-RB cows. In the contralateral uterine horn, 443 and 257 differentially expressed genes were identified in the CAR and ICAR of RB, respectively when compared with non-RB cows. Gene ontology analysis revealed that genes involved in development and morphogenesis were mainly up-regulated in the CAR of RB cows. In the ICAR of both the ipsilateral and contralateral uterine horns, genes related to the metabolic process were predominantly enriched in the RB cows when compared with non-RB cows. In the analysis of the whole uterus (combining the data above four endometrial compartments), RB cows showed up-regulation of 37 genes including PRSS2, GSTA3 and PIPOX and down-regulation of 39 genes including CHGA, KRT35 and THBS4 when compared with non-RB cows. Immunohistochemistry revealed that CHGA, GSTA3 and PRSS2 proteins

  9. Feshbach shape resonance for high Tc pairing in superlattices of quantum stripes and quantum wells

    Directory of Open Access Journals (Sweden)

    A Bianconi

    2006-09-01

    Full Text Available   The Feshbach shape resonances in the interband pairing in superconducting superlattices of quantum wells or quantum stripes is shown to provide the mechanism for high Tc superconductivity. This mechanism provides the Tc amplification driven by the architecture of material: superlattices of quantum wells (intercalated graphite or diborides and superlattices of quantum stripes (doped high Tc cuprate perovskites where the chemical potential is tuned to a Van Hove-Lifshitz singularity (vHs in the electronic energy spectrum of the superlattice associated with the change of the Fermi surface dimensionality in one of the subbands.

  10. Ab initio study of the RbSr electronic structure: Potential energy curves, transition dipole moments, and permanent electric dipole moments

    Energy Technology Data Exchange (ETDEWEB)

    Pototschnig, Johann V., E-mail: johann.pototschnig@tugraz.at; Krois, Günter; Lackner, Florian; Ernst, Wolfgang E., E-mail: wolfgang.ernst@tugraz.at [Institute of Experimental Physics, Graz University of Technology, Petersgasse 16, A-8010 Graz (Austria)

    2014-12-21

    Excited states and the ground state of the diatomic molecule RbSr were calculated by post Hartree-Fock molecular orbital theory up to 22 000 cm{sup −1}. We applied a multireference configuration interaction calculation based on multiconfigurational self-consistent field wave functions. Both methods made use of effective core potentials and core polarization potentials. Potential energy curves, transition dipole moments, and permanent electric dipole moments were determined for RbSr and could be compared with other recent calculations. We found a good agreement with experimental spectra, which have been obtained recently by helium nanodroplet isolation spectroscopy. For the lowest two asymptotes (Rb (5s {sup 2}S) + Sr (5s4d {sup 3}P°) and Rb (5p {sup 2}P°) + Sr (5s{sup 2} {sup 1}S)), which exhibit a significant spin-orbit coupling, we included relativistic effects by two approaches, one applying the Breit-Pauli Hamiltonian to the multireference configuration interaction wave functions, the other combining a spin-orbit Hamiltonian and multireference configuration interaction potential energy curves. Using the results for the relativistic potential energy curves that correspond to the Rb (5s {sup 2}S) + Sr (5s4d {sup 3}P°) asymptote, we have simulated dispersed fluorescence spectra as they were recently measured in our lab. The comparison with experimental data allows to benchmark both methods and demonstrate that spin-orbit coupling has to be included for the lowest states of RbSr.

  11. Ab initio study of the RbSr electronic structure: potential energy curves, transition dipole moments, and permanent electric dipole moments.

    Science.gov (United States)

    Pototschnig, Johann V; Krois, Günter; Lackner, Florian; Ernst, Wolfgang E

    2014-12-21

    Excited states and the ground state of the diatomic molecule RbSr were calculated by post Hartree-Fock molecular orbital theory up to 22 000 cm(-1). We applied a multireference configuration interaction calculation based on multiconfigurational self-consistent field wave functions. Both methods made use of effective core potentials and core polarization potentials. Potential energy curves, transition dipole moments, and permanent electric dipole moments were determined for RbSr and could be compared with other recent calculations. We found a good agreement with experimental spectra, which have been obtained recently by helium nanodroplet isolation spectroscopy. For the lowest two asymptotes (Rb (5s (2)S) + Sr (5s4d (3)P°) and Rb (5p (2)P°) + Sr (5s(2) (1)S)), which exhibit a significant spin-orbit coupling, we included relativistic effects by two approaches, one applying the Breit-Pauli Hamiltonian to the multireference configuration interaction wave functions, the other combining a spin-orbit Hamiltonian and multireference configuration interaction potential energy curves. Using the results for the relativistic potential energy curves that correspond to the Rb (5s (2)S) + Sr (5s4d (3)P°) asymptote, we have simulated dispersed fluorescence spectra as they were recently measured in our lab. The comparison with experimental data allows to benchmark both methods and demonstrate that spin-orbit coupling has to be included for the lowest states of RbSr.

  12. HAUFES : a FORTRAN code for the calculation of compound nuclear cross-sections by Hauser-Feshbach theory

    International Nuclear Information System (INIS)

    Viyogi, Y.P.; Ganguly, N.K.

    1975-01-01

    The FORTRAN code described in the report has been developed for the BESM-6 computer with a view to calculate the cross-section of reactions proceeding via the formation of compound nucleus for all open two-body reaction channels using Hauser-Feshbach theory with Moldauer's correction for the fluctuation of level widths. The code can also be used to analyse data from 'crystal blocking' experiments to obtain nuclear level densities. The report describes the input-output specifications along with a short account of the algorithm of the program. (author)

  13. First-principles calculations of two cubic fluoropervskite compounds: RbFeF3 and RbNiF3

    Science.gov (United States)

    Mubarak, A. A.; Al-Omari, Saleh

    2015-05-01

    We present first-principles calculations of the structural, elastic, electronic, magnetic and optical properties for RbFeF3 and RbNiF3. The full-potential linear augmented plan wave (FP-LAPW) method within the density functional theory was utilized to perform the present calculations. We employed the generalized gradient approximation as exchange-correlation potential. It was found that the calculated analytical lattice parameters agree with previous studies. The analysis of elastic constants showed that the present compounds are elastically stable and anisotropic. Moreover, both compounds are classified as a ductile compound. The calculations of the band structure and density functional theory revealed that the RbFeF3 compound has a half-metallic behavior while the RbNiF3 compound has a semiconductor behavior with indirect (M-Γ) band gap. The ferromagnetic behavior was studied for both compounds. The optical properties were calculated for the radiation of up to 40 eV. A beneficial optics technology is predicted as revealed from the optical spectra.

  14. RB research nuclear reactor - Annual report for 1986, I - III; Istrazivacki nuklearni reaktor RB (Izvestaj o radu u 1986. godini), I-III

    Energy Technology Data Exchange (ETDEWEB)

    Markovic, H; Pesic, M; Vranic, S; Petronijevic, M; Jevremovic, M; Ilic, I [Boris Kidric Institute of Nuclear Sciences Vinca, Beograd (Yugoslavia)

    1987-07-01

    This report includes data concerning the RB reactor operation in 1986, state of the reactor components, data about the employed personnel and the database of experimental and other reactor related devices. It is made of 3 parts: Engineering description and operation of the RB reactor including dosimetry, reactor staff data and financial report; Reactor facility components and maintenance; RB reactor operation and utilization in 1986. Izvestaj pokazuje podatke o radu reaktora RB u toku 1986. godine, stanje reaktorske opreme, podatke o angazovanom osoblju na reaktoru i datoteku sa podacima o eksperimentalnoj i drugoj opremi reaktora RB. Sastoji se od 3 dela: tehnicki opis, pogon i rad reaktora, oprema postrojenja i njeno odrzavanje, koriscenje reaktora u 1986. godini.

  15. RB reactor noise analysis; Analiza sumova reaktora RB

    Energy Technology Data Exchange (ETDEWEB)

    Petrovic, M; Velickovic, Lj; Markovic, V; Jovanovic, S [Institut za nuklearne nauke Boris Kidric, Vinca, Beograd (Yugoslavia)

    1964-07-01

    Statistical fluctuations of reactivity represent reactor noise. Analysis of reactor noise enables determining a series of reactor kinetic parameters. Fluctuations of power was measured by ionization chamber placed next to the tank of the RB reactor. The signal was digitized by an analog-digital converter. After calculation of the mean power, 3000 data obtained by sampling were analysed.

  16. Manipulating ultracold polar molecules with microwave radiation: The influence of hyperfine structure

    International Nuclear Information System (INIS)

    Aldegunde, J.; Hutson, Jeremy M.; Ran Hong

    2009-01-01

    We calculate the microwave spectra of ultracold 40 K 87 Rb alkali-metal dimers, including hyperfine interactions and in the presence of electric and magnetic fields. We show that microwave transitions may be used to transfer molecules between different hyperfine states, but only because of the presence of nuclear quadrupole interactions. Hyperfine splittings may also complicate the use of ultracold molecules for quantum computing. The spectrum of molecules oriented in electric fields may be simplified dramatically by applying a simultaneous magnetic field.

  17. Silencing of RB1 and RB2/P130 during adipogenesis of bone marrow stromal cells results in dysregulated differentiation.

    Science.gov (United States)

    Capasso, Stefania; Alessio, Nicola; Di Bernardo, Giovanni; Cipollaro, Marilena; Melone, Mariarosa Ab; Peluso, Gianfranco; Giordano, Antonio; Galderisi, Umberto

    2014-01-01

    Bone marrow adipose tissue (BMAT) is different from fat found elsewhere in the body, and only recently have some of its functions been investigated. BMAT may regulate bone marrow stem cell niche and plays a role in energy storage and thermogenesis. BMAT may be involved also in obesity and osteoporosis onset. Given the paramount functions of BMAT, we decided to better clarify the human bone marrow adipogenesis by analyzing the role of the retinoblastoma gene family, which are key players in cell cycle regulation. Our data provide evidence that the inactivation of RB1 or RB2/P130 in uncommitted bone marrow stromal cells (BMSC) facilitates the first steps of adipogenesis. In cultures with silenced RB1 or RB2/P130, we observed an increase of clones with adipogenic potential and a higher percentage of cells accumulating lipid droplets. Nevertheless, the absence of RB1 or RB2/P130 impaired the terminal adipocyte differentiation and gave rise to dysregulated adipose cells, with alteration in lipid uptake and release. For the first time, we evidenced that RB2/P130 plays a role in bone marrow adipogenesis. Our data suggest that while the inactivation of retinoblastoma proteins may delay the onset of last cell division and allow more BMSC to be committed to adipocyte, it did not allow a permanent cell cycle exit, which is a prerequisite for adipocyte terminal maturation.

  18. Spectroscopy of Rb atoms in hollow-core fibers

    International Nuclear Information System (INIS)

    Slepkov, Aaron D.; Bhagwat, Amar R.; Venkataraman, Vivek; Londero, Pablo; Gaeta, Alexander L.

    2010-01-01

    Recent demonstrations of light-matter interactions with atoms and molecules confined to hollow waveguides offer great promise for ultralow-light-level applications. The use of waveguides allows for tight optical confinement over interaction lengths much greater than what could be achieved in bulk geometries. However, the combination of strong atom-photon interactions and nonuniformity of guided light modes gives rise to spectroscopic features that must be understood in order to take full advantage of the properties of such systems. We use light-induced atomic desorption to generate an optically dense Rb vapor at room temperature inside a hollow-core photonic band-gap fiber. Saturable-absorption spectroscopy and passive slow-light experiments reveal large ac Stark shifts, power broadening, and transit-time broadening, that are present in this system even at nanowatt powers.

  19. Radiation protection at reactors RA and RB

    International Nuclear Information System (INIS)

    Ninkovic, M.

    2003-02-01

    Radiation protection activities at the RA and RB reactors are imposed by the existing legal regulations and international recommendations in this field. This annual report contains five parts which cover the following topics: Radiation safety, dosimetry control and technical radiation protection at reactors RA and RB; Handling of radioactive waste, actions and decontamination; Control of the environment (surroundings of RA and RB reactors) and meteorological measurements; Control of internal contamination and internal exposure; Health control od personnel exposed to radiation. Personnel as well as financial data are part of this report

  20. Formation of H_2^+ and its Isotopomers by Radiative Association: the Role of Shape and Feshbach Resonances

    Science.gov (United States)

    Beyer, Maximilian; Merkt, Frederic

    2017-06-01

    The recent observations [1,2] of shape and Feshbach resonances in the high-resolution photoelectron spectra of H_2, HD and D_2 in the vicinity of the dissociation thresholds of H_2^+, HD^+ and D_2^+ raise questions concerning their potential role in the formation of H_2^+ and its isotopomers in the early universe by radiative association, a topic of astrophysical interest [3]. Close-coupling calculations for the cross sections of the reactions {H}^+ + {H} &\\to {H}_2^+ + hν {H}^+ + {D} &\\to {HD}^+ + hν {D}^+ + {H} &\\to {HD}^+ + hν {D}^+ + {D} &\\to {D}_2^+ + hν, will be presented which take into account nonadiabatic couplings involving rovibronic and hyperfine interactions, as well as relativistic and radiative corrections. The calculated energies and widths will be compared with the experimental results of Ref. [1,2] for H_2^+ and new data for HD^+ and D_2^+. The effect of the resonances on the radiative association rate coefficients will be discussed, also in comparison with earlier studies [4]. [1] M. Beyer and F. Merkt, Phys. Rev. Lett. 116, 093001 (2016). [2] M. Beyer and F. Merkt, J. Mol. Spectrosc. 330, 147 (2016). [3] Molecule formation in dust-poor environments, J. F. Babb and K. P. Kirby, in "The molecular astrophysics of stars and galaxies", T. W. Hartquist and D. A. Williams, eds., Oxford University Press, Oxford, 1998, pp. 11-34. [4] D. E. Ramaker and J. M. Peek, Phys. Rev. A 13, 58 (1976).

  1. Radiative neutron capture: Hauser Feshbach vs. statistical resonances

    Energy Technology Data Exchange (ETDEWEB)

    Rochman, D., E-mail: dimitri-alexandre.rochman@psi.ch [Reactor Physics and Systems Behavior Laboratory, Paul Scherrer Institute, Villigen (Switzerland); Goriely, S. [Institut d' Astronomie et d' Astrophysique, CP-226, Université Libre de Bruxelles, 1050 Brussels (Belgium); Koning, A.J. [Nuclear Data Section, IAEA, Vienna (Austria); Uppsala University, Uppsala (Sweden); Ferroukhi, H. [Reactor Physics and Systems Behavior Laboratory, Paul Scherrer Institute, Villigen (Switzerland)

    2017-01-10

    The radiative neutron capture rates for isotopes of astrophysical interest are commonly calculated on the basis of the statistical Hauser Feshbach (HF) reaction model, leading to smooth and monotonically varying temperature-dependent Maxwellian-averaged cross sections (MACS). The HF approximation is known to be valid if the number of resonances in the compound system is relatively high. However, such a condition is hardly fulfilled for keV neutrons captured on light or exotic neutron-rich nuclei. For this reason, a different procedure is proposed here, based on the generation of statistical resonances. This novel technique, called the “High Fidelity Resonance” (HFR) method is shown to provide similar results as the HF approach for nuclei with a high level density but to deviate and be more realistic than HF predictions for light and neutron-rich nuclei or at relatively low sub-keV energies. The MACS derived with the HFR method are systematically compared with the traditional HF calculations for some 3300 neutron-rich nuclei and shown to give rise to significantly larger predictions with respect to the HF approach at energies of astrophysical relevance. For this reason, the HF approach should not be applied to light or neutron-rich nuclei. The Doppler broadening of the generated resonances is also studied and found to have a negligible impact on the calculated MACS.

  2. Dosimetry system of the RB reactor; Dozimetarski sistem reaktora RB

    Energy Technology Data Exchange (ETDEWEB)

    Lolic, B; Vukadin, D [Boris Kidric Institute of nuclear sciences, Vinca, Belgrade (Yugoslavia)

    1962-07-01

    Although RB reactor is operated at very low power levels, safety and dosimetry systems have high importance. This paper shows detailed dosimetry system with fundamental typical components. Estimated radiation doses dependent on reactor power are given at some characteristic points in the rooms nearby reactor.

  3. Lattice Dynamics of NaCI, KCI, RbCl and RbF

    Energy Technology Data Exchange (ETDEWEB)

    Raunio, G; Rolandson, S [Physics Dept., Chalmers Univ. of Technology, Goet eborg (Sweden)

    1970-07-01

    In a series of earlier papers experimental results on phonon dispersion relations at 80 K in NaCl, KCl, RbCl and RbF have been reported. We now present calculations on these halides using the extended shell model approach with both ions polarizable and including next-nearest neighbour interactions. The parameters obtained in a least squares fit to the experimental points in the symmetry directions have been used to calculate the phonon frequencies in 512,000 equally spaced points in an octant of the Brillouin zone, -whereby, after sorting these into intervals of width {delta}{omega} = 2 x 10{sup 11} rad/sec , the frequency spectrum was obtained. From these spectra the variation of the Debye temperature with temperature was also calculated. The agreement with results from specific heat measurements for NaCl and KCl is quite satisfactory at low temperatures.

  4. RB Research nuclear reactor, 30 years of operation; Istrazivacki nuclearni reaktor RB, povodom 30 godina rada

    Energy Technology Data Exchange (ETDEWEB)

    Pesic, M; Stefanovic, D [Boris Kidric Institute of nuclear sciences Vinca, Belgrade (Yugoslavia)

    1988-06-15

    Paper describes utilization, modifications and changes of construction and control-safety systems done at the RB reactor during 30 years of operation. Experiments performed at the reactor are summarized, new reactor equipment is described and the future plans are shown. Rad prikazuje eksploataciju reaktora RB tokom 30 godina rada, modifikacije i izmene u konstruktivnim i upravljacko-sigurnosnim sistemima. Sumirani su eksperimenti izvedeni na njemu, prikazana je nova oprema i planovi za buduci rad.

  5. Simple discretization method for autoionization widths. III. Molecules

    International Nuclear Information System (INIS)

    Macas, A.; Martn, F.; Riera, A.; Yanez, M.

    1987-01-01

    We apply a new method to calculate widths of two-electron Feshbach resonances, which was described in detail and applied to atomic systems in preceding articles (this issue), to molecular and quasimolecular autoionizing states. For simplicity in the programming effort, we restrict our calculations to the small-R region where one-centered expansions are sufficiently accurate to describe the wave functions. As test cases, positions and widths for the H 2 , He 2 /sup 2+/, HeH + , and LiHe/sup 3+/ resonances of lowest energy are computed for R<0.6 a.u. The advantage of using block-diagonalization techniques to define diabatic resonant states instead of generalizing the Feshbach formalism is pointed out

  6. Molecular (Feshbach) treatment of charge exchange Li3++He collisions. I. Energies and couplings

    International Nuclear Information System (INIS)

    Martin, F.; Riera, A.; Yanez, M.

    1986-01-01

    We point out a fundamental difference between the molecular treatment of charge exchange X/sup n/++H(1s) and X/sup n/++He(1s 2 ) collisions, which is that the latter process involves molecular states that are formally autoionizing. Then standard ab initio methods do not, in general, yield the relevant wave functions that are needed in the collision treatment, irrespective of whether quasimolecular autoionization be significant or not during the collision. We implement a particularly simple and useful form of the Feshbach formalism to calculate the energies of those two electron systems, and a method to evaluate the corresponding dynamical couplings is presented for the first time. Our implementation of this formalism together with the new computational techniques involved are presented in detail

  7. RB research nuclear reactor, Annual report for 1981; Istrazivacki nuklearni reaktor RB, Izvestaj o radu u 1981. godini

    Energy Technology Data Exchange (ETDEWEB)

    Markovic, H; Sotic, O; Pesic, M; Vranic, S; Zivkovic, B; Bogdanovic, M; Petronijevic, M [Boris Kidric Institute of Nuclear Sciences Vinca, Beograd (Yugoslavia)

    1981-07-01

    The annual report for 1981 includes the following: utilization of the RB reactor; accident and incidents analysis; description of the reactor equipment status; dosimetry and radiation protection; RB reactor staff; financial data. Seven Annexes to this report are concerned with: maintenance of the reactor components and equipment, including nuclear fuel, heavy water, reactor vessel, heavy water coolant circuit, experimental platforms, absorption rods; maintenance of the electric power supply system, neutron source equipment, crane; control and maintenance of ventilation and heating systems, gas and comprised gas systems, fire protection system; plan for renewal of the reactor components; contents of the RB reactor safety report; reactor staff; review of measured radiation doses; experimental methods; training of the staff; and financial report.

  8. 87Rb-NMR in Rb2ZnCl4 below the incommensurable phase

    International Nuclear Information System (INIS)

    Grande, S.; Moskvich, Yu.N.; Aleksandrova, I.P.

    1983-01-01

    In Rb 2 ZnCl 4 crystals the curly polar phase, which changes into the incommensurable phase below 192 K, has been investigated by pulsed NMR. The angular correlations of the second-order quadrupole shifts have been measured and the corresponding tensors of the electric field gradient have been calculated. The six Rb layers change differently in magnitude and orientation compared to the paraelectric phase. The temperature dependences within the C-phase are also different. The spin-lattice relaxation times have been measured and discussed for each layer in the C-phase. All relaxation times show an anomaly at a further phase transition occurring at 72 K connected with an increase of the number of spectral lines

  9. Soft X-ray synchrotron radiation spectroscopy study of molecule-based nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Lee, E. S.; Kim, D. H.; Kang, J. S.; Kim, P. [The Catholic University of Korea, Bucheon (Korea, Republic of); Kim, K. H. [Korea University, Jochiwon (Korea, Republic of); Baik, J. Y.; Shin, H. J. [POSTECH, Pohang (Korea, Republic of)

    2014-11-15

    The electronic structures of molecule-based nanoparticles, such as biomineralized Helicobacter pylori ferritin (Hpf), Heme, and RbCo[Fe(CN){sub 6}]H{sub 2}O (RbCoFe) Prussian blue analogue, have been investigated by employing photoemission spectroscopy and soft X-ray absorption spectroscopy. Fe ions are found to be nearly trivalent in Hpf and Heme nanoparticles, which provides evidence that the amount of magnetite (Fe{sub 3}O{sub 4}) should be negligible in the Hpf core and that the biomineralization of Fe oxides in the high-Fe-bound-state Hpf core arises from a hematite-like formation. On the other hand, Fe ions are nearly divalent and Co ions are Co{sup 2+}-Co{sup 3+} mixed-valent in RbCoFe. Therefore this finding suggests that the mechanism of the photo-induced transition in RbCoFe Prussian blue analogue is not a simple spin-state transition of Fe{sup 2+}-Co{sup 3+} → Fe{sup 3+}-Co{sup 2+}. It is likely that Co{sup 2+} ions have the high-spin configuration while Fe{sup 2+} ions have the low-spin configuration.

  10. Universal relations between Feshbach resonances and molecules

    NARCIS (Netherlands)

    Goosen, M.R.

    2011-01-01

    The susceptibility of ultracold gases to precise manipulation via external fields makes them ideal systems to study fundamental quantum mechanical phenomena. Various regimes, which are not possible to reach in condensed matter or nuclear physics, can be probed with these quantum gases. Especially

  11. A consistent analysis of (p,p`) and (n,n`) reactions using the Feshbach-Kerman-Koonin model

    Energy Technology Data Exchange (ETDEWEB)

    Yoshioka, S.; Watanabe, Y.; Harada, M. [Kyushu Univ., Fukuoka (Japan)] [and others

    1997-03-01

    Double-differential proton emission cross sections were measured for proton-induced reactions on several medium-heavy nuclei ({sup 54,56}Fe, {sup 60}Ni, {sup 90}Zr, and {sup 93}Nb) at two incident energies of 14.1 and 26 MeV. The (p,p`) data for {sup 56}Fe and {sup 93}Nb were compared with available data of (n,n`) scattering for the same target nuclei and incident energies, and both data were analyzed using the Feshbach-Kerman-Koonin model to extract the strength V{sub 0} of the effective N-N interaction which is the only free parameter used in multistep direct calculations. (author)

  12. Time-dependent quantum chemistry of laser driven many-electron molecules

    International Nuclear Information System (INIS)

    Nguyen-Dang, Thanh-Tung; Couture-Bienvenue, Étienne; Viau-Trudel, Jérémy; Sainjon, Amaury

    2014-01-01

    A Time-Dependent Configuration Interaction approach using multiple Feshbach partitionings, corresponding to multiple ionization stages of a laser-driven molecule, has recently been proposed [T.-T. Nguyen-Dang and J. Viau-Trudel, J. Chem. Phys. 139, 244102 (2013)]. To complete this development toward a fully ab-initio method for the calculation of time-dependent electronic wavefunctions of an N-electron molecule, we describe how tools of multiconfiguration quantum chemistry such as the management of the configuration expansion space using Graphical Unitary Group Approach concepts can be profitably adapted to the new context, that of time-resolved electronic dynamics, as opposed to stationary electronic structure. The method is applied to calculate the detailed, sub-cycle electronic dynamics of BeH 2 , treated in a 3–21G bound-orbital basis augmented by a set of orthogonalized plane-waves representing continuum-type orbitals, including its ionization under an intense λ = 800 nm or λ = 80 nm continuous-wave laser field. The dynamics is strongly non-linear at the field-intensity considered (I ≃ 10 15 W/cm 2 ), featuring important ionization of an inner-shell electron and strong post-ionization bound-electron dynamics

  13. 76 FR 24793 - Airworthiness Directives; Rolls-Royce plc (RR) RB211-524 Series and RB211 Trent 500, 700, and 800...

    Science.gov (United States)

    2011-05-03

    ... Airworthiness Directives; Rolls-Royce plc (RR) RB211-524 Series and RB211 Trent 500, 700, and 800 Series... the AD. Costs of Compliance Based on the service information, we estimate that this AD would affect...

  14. New neutron and gamma dosimetry equipment at the RB reactor; Nova merna neutronska i gama dozimetrijska oprema na reaktoru RB

    Energy Technology Data Exchange (ETDEWEB)

    Pesic, M; Stefanovic, D; Jevremovic, M; Petronijevic, M; Vranic, S; Ilic, I [Boris Kidric Institute of Nuclear Sciences Vinca, Beograd (Yugoslavia)

    1992-07-15

    In the frame of bilateral cooperation between Germany and Yugoslavia, complete control, safety and dosimetry equipment of the shut-down SNEAK reactor was donated to Vinca Institute and transported to be installed at the RB reactor. This report contains detailed description of instrumentation components including detectors, electronic components and electronic circuits. Experimental data which verified correct functioning of the installed devices are part of this document. The objective of the RB reactor staff is to achieve new safety and dosimetry system in order to improve the reliability and availability of the RB reactor for future experiments.

  15. Realizing Fulde-Ferrell Superfluids via a Dark-State Control of Feshbach Resonances

    Science.gov (United States)

    He, Lianyi; Hu, Hui; Liu, Xia-Ji

    2018-01-01

    We propose that the long-sought Fulde-Ferrell superfluidity with nonzero momentum pairing can be realized in ultracold two-component Fermi gases of K 40 or Li 6 atoms by optically tuning their magnetic Feshbach resonances via the creation of a closed-channel dark state with a Doppler-shifted Stark effect. In this scheme, two counterpropagating optical fields are applied to couple two molecular states in the closed channel to an excited molecular state, leading to a significant violation of Galilean invariance in the dark-state regime and hence to the possibility of Fulde-Ferrell superfluidity. We develop a field theoretical formulation for both two-body and many-body problems and predict that the Fulde-Ferrell state has remarkable properties, such as anisotropic single-particle dispersion relation, suppressed superfluid density at zero temperature, anisotropic sound velocity, and rotonic collective mode. The latter two features can be experimentally probed using Bragg spectroscopy, providing a smoking-gun proof of Fulde-Ferrell superfluidity.

  16. Precision study of the $\\beta$-decay of $^{74}$Rb

    CERN Multimedia

    Van Duppen, P L E; Lunney, D

    2002-01-01

    We are proposing a high-resolution study of the $\\beta$-decay of $^{74}$Rb in order to extrapolate our precision knowledge of the superallowed $\\beta$-decays from the sd and fp shells towards the medium-heavy Z=N nuclei. The primary goal is to provide new data for testing the CVC hypothesis and the unitarity condition of the CKM matrix of the Standard Model. The presented programme would involve the careful measurements of the decay properties of $^{74}$Rb including the branching ratios to the excited states as well as the precise determination of the decay energy of $^{74}$Rb. The experimental methods readily available at ISOLDE include high-transmission conversion electron spectroscopy, $\\gamma$-ray spectroscopy as well as the measurements of the masses of $^{74}$Rb and $^{74}$Kr using two complementary techniques, ISOLTRAP and MISTRAL. The experiment would rely on a high-quality $^{74}$Rb beam available at ISOLDE with adequate intensity.

  17. A structural phase transition coupled to the Fe{sup 3+} spin-state crossover in anhydrous RbMn[Fe(CN){sub 6}

    Energy Technology Data Exchange (ETDEWEB)

    Rykov, A. I., E-mail: rykov3@yahoo.com; Wang, J., E-mail: wangjh@dicp.ac.cn; Zhang, T. [Chinese Academy of Sciences, Moessbauer Effect Data Center, Dalian Institute of Chemical Physics (China); Nomura, K. [University of Tokyo, Graduate School of Engineering (Japan)

    2013-04-15

    Linkage isomerism is the coexistence of iso-compositional molecules or solids differing by connectivity of the metal to a ligand. In a crystalline solid state, the rotation is possible for asymmetric ligands, e.g., for cyanide ligand. Here we report on our observation of a phase transition in anhydrous RbMn[Fe(CN){sub 6}] (nearly stoichiometric) and on the effect of linkage isomerism ensuing our interpretation of the results of Moessbauer study in which we observe the iron spin state crossover among two phases involved into this transition. The anhydrous RbMn[Fe(CN){sub 6}] can be prepared via prolonged thermal treatment (1 week at at 80 Degree-Sign C) of the as-synthesized hydrated RbMn[Fe(CN){sub 6}]{center_dot}H{sub 2}O. The latter compound famous for its charge-transfer phase transition is a precursor in our case. As the temperature is raising above 80 Degree-Sign C (remaining below 100 Degree-Sign C) we observe RbMn[Fe(CN){sub 6}] that inherited its F-43 m symmetry from RbMn[Fe(CN){sub 6}]{center_dot}H{sub 2}O transforming to a phase of the Fm-3 m symmetry. In the latter, more than half of Fe{sup 3 + } ions are in high-spin state. We suggest a plausible way to explain the spin-crossover that is to allow the linkage isomerism by rotation of the cyanide ligands.

  18. Hydrothermal synthesis and polymorphism of RbPr(MoO4)2

    International Nuclear Information System (INIS)

    Protasova, V.I.; Kharchenko, L.Yu.; Klevtsov, P.V.

    1977-01-01

    Hydrothermal method has been successfully used to obtain crystals of rubidium-rare-earth molibdates of RbLn(MoO 4 ) 2 composition (Ln is a rare earth element). In Rb 2 MoO 4 solutions at 575-600degC the RbPr(MoO 4 ) 2 crystals were obtained in a modification new for Rb-Ln-molibdates, i.e. isostructural to triclinic α-KEu(MoO 4 ) 2 , and in a structural modification of laminated rhombic KY(MoO 4 ) 2 type. Polymorphism of RbPr(MoO 4 ) 2 has been studied, four crystalline modifications found and their complex interchanges investigated

  19. The RB/E2F pathway and regulation of RNA processing

    Energy Technology Data Exchange (ETDEWEB)

    Ahlander, Joseph [Department of Molecular and Cellular Biology, 1007 East Lowell Street, University of Arizona, Tucson, AZ 85721 (United States); Bosco, Giovanni, E-mail: gbosco@email.arizona.edu [Department of Molecular and Cellular Biology, 1007 East Lowell Street, University of Arizona, Tucson, AZ 85721 (United States)

    2009-07-03

    The retinoblastoma tumor suppressor protein (RB) is inactivated in a majority of cancers. RB restricts cell proliferation by inhibiting the E2F family of transcription factors. The current model for RB/E2F function describes its role in regulating transcription at gene promoters. Whether the RB or E2F proteins might play a role in gene expression beyond transcription initiation is not well known. This review describes evidence that points to a novel role for the RB/E2F network in the regulation of RNA processing, and we propose a model as a framework for future research. The elucidation of a novel role of RB in RNA processing will have a profound impact on our understanding of the role of this tumor suppressor family in cell and developmental biology.

  20. Ouabain-sensitive Rb+ uptake in mouse eggs and preimplantation conceptuses

    International Nuclear Information System (INIS)

    Van Winkle, L.J.; Campione, A.L.

    1991-01-01

    The results of histochemical and immunocytochemical studies have been used elsewhere to support the hypothesis that Na+/K(+)-ATPase expression is initiated or increases dramatically in preimplantation mouse conceptuses just before they begin to cavitate. Moreover, localization of the enzyme in the inner membrane of the mural trophoblast is thought to be involved directly in formation and maintenance of the blastocyst cavity. Presumably, Na+/K(+)-ATPase extrudes the cation, Na+, and therefore water into the cavity. The cation transporting activity of the enzyme can be determined by measuring ouabain-sensitive Rb+ uptake by cells. Therefore, we measured Rb+ uptake in mouse eggs and preimplantation conceptuses at various stages of development. 86Rb+ uptake by conceptuses increased linearly with time for at least 60 min in medium containing 0.7 mM total Rb+ plus K+ in the absence or presence of 1.0 mM ouabain, and ouabain inhibited more than 70% of 86Rb+ uptake. The ouabain concentration at 1/2 of maximum inhibition of the ouabain-sensitive component of 86Rb+ uptake was about 10-20 microM in eggs and conceptuses at all stages of preimplantation development. Moreover, ouabain-sensitive Rb+ uptake had a twofold higher Vmax value in blastocysts than in eggs or conceptuses at earlier stages of development (i.e., approximately 173 vs 70-100 fmole.conceptus-1.min-1), although the total cell surface area also was probably about two times greater in blastocysts than in eggs or other conceptuses. Ouabain-sensitive Rb+ transport in eggs and conceptuses may have occurred via a single ouabain-sensitive Rb+ transporter with a Hill coefficient of 1.5-1.8 (Hill plots). When it was assumed that the Hill coefficient had a value of 2.0, however, eggs and conceptuses appeared to contain at least two forms of Na+/K(+)-ATPase activity

  1. Nuclear RB research reactor. Thirty years of anniversary; Istrazhivacki nuklearni reaktor RB. Povodom 30 godina rada

    Energy Technology Data Exchange (ETDEWEB)

    Pesic, M; Stefanovic, D [Institut za Nuklearne Nauke Boris Kidric, Belgrade (Yugoslavia)

    1988-07-01

    Nuclear research reactor RB in the Nuclear Engineering Laboratory - NET at the 'Boris Kidric' Institute of Nuclear Sciences in Vinca is the first reactor system built in Yugoslavia in 1958. This year is the thirtieth anniversary of the RB reactor operation, which has survived a series of modifications trying to follow a contemporary nuclear research directions. This report describes its basic technical characteristics and experimental possibilities. Especially, the modifications in the last 25 years are underlined, the experiences gained, and new plans for the future are presented. (author)

  2. Thermodynamic studies of (RbF + RbCl + H2O) and (CsF + CsCl + H2O) ternary systems from potentiometric measurements at T = 298.2 K

    International Nuclear Information System (INIS)

    Huang, Xiaoting; Li, Shu’ni; Zhai, Quanguo; Jiang, Yucheng; Hu, Mancheng

    2016-01-01

    Graphical abstract: Thermodynamic properties, such as mean activity coefficients, osmotic coefficients and excess Gibbs free energies, of the RbF + RbCl + H 2 O and CsF + CsCl + H 2 O ternary systems were determined from potentiometric measurement at 298.2 K. The Pitzer model and the Harned rule were used to fit the experimental data. - Highlights: • Thermodynamic properties of RbF + RbCl + H 2 O and CsF + CsCl + H 2 O ternary systems were determined. • The Pitzer model and the Harned rule were used to correlate the experimental data. • The mean activity coefficients, osmotic coefficients, and the excess Gibbs free energy were also obtained. - Abstract: Thermodynamic properties of (RbF + RbCl + H 2 O) and (CsF + CsCl + H 2 O) systems were determined by the potentiometric method for different ionic strength fractions y B of RbCl/CsCl at 298.2 K. The Pitzer model and the Harned rule were used to fit the experimental values. The Pitzer mixing parameters and the Harned coefficients were evaluated. In addition, the mean ionic activity coefficients of RbF/CsF and RbCl/CsCl, the osmotic coefficients, and the excess Gibbs energies of the systems studied were calculated.

  3. Calibration of RB reactor power

    International Nuclear Information System (INIS)

    Sotic, O.; Markovic, H.; Ninkovic, M.; Strugar, P.; Dimitrijevic, Z.; Takac, S.; Stefanovic, D.; Kocic, A.; Vranic, S.

    1976-09-01

    The first and only calibration of RB reactor power was done in 1962, and the obtained calibration ratio was used irrespective of the lattice pitch and core configuration. Since the RB reactor is being prepared for operation at higher power levels it was indispensable to reexamine the calibration ratio, estimate its dependence on the lattice pitch, critical level of heavy water and thickness of the side reflector. It was necessary to verify the reliability of control and dosimetry instruments, and establish neutron and gamma dose dependence on reactor power. Two series of experiments were done in June 1976. First series was devoted to tests of control and dosimetry instrumentation and measurements of radiation in the RB reactor building dependent on reactor power. Second series covered measurement of thermal and epithermal neuron fluxes in the reactor core and calculation of reactor power. Four different reactor cores were chosen for these experiments. Reactor pitches were 8, 8√2, and 16 cm with 40, 52 and 82 fuel channels containing 2% enriched fuel. Obtained results and analysis of these results are presented in this document with conclusions related to reactor safe operation

  4. RB research nuclear reactor, Annual report for 1982; Istrazivacki nuklearni reaktor RB, Izvestaj o radu u 1981. godini

    Energy Technology Data Exchange (ETDEWEB)

    Markovic, H; Pesic, M; Vranic, S; Petronijevic, M; Zivkovic, B [Boris Kidric Institute of Nuclear Sciences Vinca, Beograd (Yugoslavia)

    1982-12-15

    This report includes data concerned with reactor operation and utilization, status of reactor components and equipment, refurbishment of the equipment, dosimetry and radiation protection, reactor staff, financing. It includes 7 Annexes as follows: Maintenance of reactor equipment in 1982; contents of the RB reactor safety report; review of radiation doses in the reactor building and exposure doses for the reactor staff; utilization of the RB reactor in 1982; and financial data.

  5. Human biodistribution and radiation dosimetry of 82Rb.

    Science.gov (United States)

    Senthamizhchelvan, Srinivasan; Bravo, Paco E; Esaias, Caroline; Lodge, Martin A; Merrill, Jennifer; Hobbs, Robert F; Sgouros, George; Bengel, Frank M

    2010-10-01

    Prior estimates of radiation-absorbed doses from (82)Rb, a frequently used PET perfusion tracer, yielded discrepant results. We reevaluated (82)Rb dosimetry using human in vivo biokinetic measurements. Ten healthy volunteers underwent dynamic PET/CT (6 contiguous table positions, each with separate (82)Rb infusion). Source organ volumes of interest were delineated on the CT images and transferred to the PET images to obtain time-integrated activity coefficients. Radiation doses were estimated using OLINDA/EXM 1.0. The highest mean absorbed organ doses (μGy/MBq) were observed for the kidneys (5.81), heart wall (3.86), and lungs (2.96). Mean effective doses were 1.11 ± 0.22 and 1.26 ± 0.20 μSv/MBq using the tissue-weighting factors of the International Commission on Radiological Protection (ICRP), publications 60 and 103, respectively. Our current (82)Rb dosimetry suggests reasonably low radiation exposure. On the basis of this study, a clinical (82)Rb injection of 2 × 1,480 MBq (80 mCi) would result in a mean effective dose of 3.7 mSv using the weighting factors of the ICRP 103-only slightly above the average annual natural background exposure in the United States (3.1 mSv).

  6. 86Rb Distribution in the Lung of the Rabbit with Pneumothorax

    International Nuclear Information System (INIS)

    Huh, Kap To

    1972-01-01

    86 Rb uptake of some organs and tissues, eg. both lungs, both renal cortices. small intestine, liver and skeletal muscle were studied in the control and the rabbit subjected to pneumothorax. 86 Rb in the form of chloride mixed with physiological saline was intravenously injected. The doses were 100 μc for a rabbit. The rabbits were sacrificed at intervals of 10, 20, 40, and 60 seconds after the injection of 86 Rb, by the injection of saturated KCI solution. After scarification, the organ and tissue sample were quickly removed. 86 Rb uptake in gm of the organs and tissues were measured. On the basis of uptake value, administered doses and body weight, % dose/gm tissues per 200 gm body weight was calculated. Followings were the results: 1. Pneumothorax resulted in a marked elevation in 86 Rb uptake value of collapsed lung and returned to normal level lately. 2. Contralateral lung of pneumothorax also showed marked elevation in 86 Rb uptake value and recovered to normal level. 3. Initial 86 Rb uptake value of liver, small intestine of the rabbit with pneumothorax showed some elevation as compared to control, but that of late stage were similar with control. 4. Local blood flow determination by means of 86 Rb uptake were inadequate in the collapsed lung of pneumothorax. 5. It was suggested that the mechanism for the initial elevation of 86 Rb uptake value in each organs and tissue were different from each other.

  7. RB1 mutation spectrum in a comprehensive nationwide cohort of retinoblastoma patients

    NARCIS (Netherlands)

    Dommering, Charlotte J.; Mol, Berber M.; Moll, Annette C.; Burton, Margaret; Cloos, Jacqueline; Dorsman, Josephine C.; Meijers-Heijboer, Hanne; van der Hout, Annemarie H.

    Background Retinoblastoma (Rb) is a childhood cancer of the retina, commonly initiated by biallelic inactivation of the RB1 gene. Knowledge of the presence of a heritable RB1 mutation can help in risk management and reproductive decision making. We report here on RB1 mutation scanning in a unique

  8. Fast neutron fields at the RB reactor; Polja brzih neutron na reacktoru RB

    Energy Technology Data Exchange (ETDEWEB)

    Strugar, P; Pesic, M; Dasic, N [Institut za nuklearne nauke Boris Kidric Vinca, Beograd (Yugoslavia)

    1984-07-01

    Paper deals with the reasons and methods of realization of the RB neutron converters. The methods and results of neutron flux intensities and spectra measurements as well as gamma dose determination are presented. (author)

  9. Molecular (Feshbach) treatment of charge exchange Li/sup 3 +/+He collisions. I. Energies and couplings

    Energy Technology Data Exchange (ETDEWEB)

    Martin, F.; Riera, A.; Yanez, M.

    1986-05-15

    We point out a fundamental difference between the molecular treatment of charge exchange X/sup n/++H(1s) and X/sup n/++He(1s/sup 2/) collisions, which is that the latter process involves molecular states that are formally autoionizing. Then standard ab initio methods do not, in general, yield the relevant wave functions that are needed in the collision treatment, irrespective of whether quasimolecular autoionization be significant or not during the collision. We implement a particularly simple and useful form of the Feshbach formalism to calculate the energies of those two electron systems, and a method to evaluate the corresponding dynamical couplings is presented for the first time. Our implementation of this formalism together with the new computational techniques involved are presented in detail.

  10. Synthesis and Characterization of the Rubidium Thiophosphate Rb 6 (PS 5 )(P 2 S 10 ) and the Rubidium Silver Thiophosphates Rb 2 AgPS 4 , RbAg 5 (PS 4 ) 2 and Rb 3 Ag 9 (PS 4 ) 4

    KAUST Repository

    Alahmary, Fatimah S.

    2016-02-18

    The metal thiophosphates Rb2AgPS4 (2), RbAg5(PS4)2 (3), and Rb3Ag9(PS4)4 (4) were synthesized by stoichiometric reactions, whereas Rb6(PS5)(P2S10) (1) was prepared with excess amount of sulfur. The compounds crystallize as follows: 1 monoclinic, P21/c (no. 14), a = 17.0123(7) Å, b = 6.9102(2) Å, c = 23.179(1) Å, β = 94.399(4)°; 2 triclinic, P ¯ (no. 2), a = 6.600(1) Å, b = 6.856(1) Å, c = 10.943(3) Å, α = 95.150(2)°, β = 107.338(2)°, γ = 111.383(2)°; 3 orthorhombic, Pbca (no. 61), a = 12.607(1) Å, b = 12.612(1) Å, c = 17.759(2) Å; 4 orthorhombic, Pbcm (no. 57), a = 6.3481(2) Å, b = 12.5782(4) Å, c = 35.975(1) Å. The crystal structures contain discrete units, chains, and 3D polyanionic frameworks composed of PS4 tetrahedral units arranged and connected in different manner. Compounds 1-3 melt congruently, whereas incongruent melting behavior was observed for compound 4. 1-4 are semiconductors with bandgaps between 2.3 and 2.6 eV and thermally stable up to 450 °C in an inert atmosphere. Copyright © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Optical pumping in a microfabricated Rb vapor cell using a microfabricated Rb discharge light source

    International Nuclear Information System (INIS)

    Venkatraman, V.; Kang, S.; Affolderbach, C.; Mileti, G.; Shea, H.

    2014-01-01

    Miniature ( 3 ) vapor-cell based devices using optical pumping of alkali atoms, such as atomic clocks and magnetometers, today mostly employ vertical-cavity surface-emitting lasers as pump light sources. Here, we report on the demonstration of optical pumping in a microfabricated alkali vapor resonance cell using (1) a microfabricated Rb discharge lamp light source, as well as (2) a conventional glass-blown Rb discharge lamp. The microfabricated Rb lamp cell is a dielectric barrier discharge (DBD) light source, having the same inner cell volume of around 40 mm 3 as that of the resonance cell, both filled with suitable buffer gases. A miniature (∼2 cm 3 volume) test setup based on the M z magnetometer interrogation technique was used for observation of optical-radiofrequency double-resonance signals, proving the suitability of the microfabricated discharge lamp to introduce efficient optical pumping. The pumping ability of this light source was found to be comparable to or even better than that of a conventional glass-blown lamp. The reported results indicate that the micro-fabricated DBD discharge lamp has a high potential for the development of a new class of miniature atomic clocks, magnetometers, and quantum sensors

  12. Study of compoisiton of saturated vapor of MF-CuF2 systems, where M=K, Rb, Cs

    International Nuclear Information System (INIS)

    Morozov, I.V.; Korenev, Yu.M.

    1993-01-01

    Investigation into composition of saturated vapor of MF-CuF 2 systems where M=K, Rb, Cs is conducted using high-temperature mass-spectrometry. Existence of MCuF 3 molecules in gas phase is determined. MCuF 3(r) dissociation enthalpies are calculated using the first law-of thermodynamics and are compared with theoretically determined values. Value Δ D G 0 944 (CsCuF 3(r) =105.6±6.3 kj/mol is determined

  13. 75 FR 51654 - Airworthiness Directives; Rolls-Royce plc (RR) RB211-22B and RB211-524 Series Turbofan Engines

    Science.gov (United States)

    2010-08-23

    ... Airworthiness Directives; Rolls-Royce plc (RR) RB211-22B and RB211-524 Series Turbofan Engines AGENCY: Federal... that air safety and the public interest require adopting the AD as proposed. Costs of Compliance Based... labor rate is $85 per work-hour. Required parts will cost about $15,000 per product. Based on these...

  14. Biosafety of parenteral Brucella abortus RB51 vaccine in bison calves

    Science.gov (United States)

    Roffe, T.J.; Olsen, S.C.; Gidlewski, T.; Jensen, A.E.; Palmer, M.V.; Huber, R.

    1999-01-01

    Vaccination is considered among the primary management tools for reducing brucellosis prevalence in Greater Yellowstone Area (GYA) ungulates. Before their use, however, vaccine safety and efficacy must be demonstrated. Twenty-seven female bison (Bison bison) calves (approx 5 months old) were vaccinated with Brucella abortus Strain RB51 (1.5 x 1010 colony forming units [CFU], subcutaneously) as part of routine management. We assessed the persistence, pathology, shedding, and transmission associated with RB51 by serial necropsy, bacteriology, histopathology, and serology of 20 of these 27 vaccinated calves, and RB51 serology of 10 nonvaccinated, commingling adult females. With the exception of 1 calf, RB51 dot-blot titers at necropsy were <1:80. Strain RB51 was cultured from lymph nodes in 4 of 4 calves at 14 weeks postvaccination (PV), 4 of 4 calves at 18 weeks PV, 1 of 4 calves at 22 weeks PV, 3 of 4 at 26 weeks PV, and 0 of 4 calves at 30 weeks PV. No gross lesions were observed. Mild histologic changes occurred only in a few draining lymph nodes early in sampling. Adverse clinical effects were not observed in vaccinates. Swabs from nasopharynx, conjunctiva, rectum, and vagina were uniformly culture negative for RB51. Strain RB51 dot-blot assays of bison cows were negative at a 1:20 dilution at 26 weeks PV. Our results suggest that RB51 persists longer in bison calves than in domestic cattle and is systemically distributed within lymphatic tissues. However, bison apparently clear the RB51 vaccine strain without shedding, transmission, or significant adverse reactions.

  15. Absolute transition intensities in decay of 92Rb

    International Nuclear Information System (INIS)

    Lhersonneau, G.; Rizzi, V.; Barzakh, A.

    2005-01-01

    In a first step studied the evolution of the ion current of 92 Rb and 94 Sr produced by surface ionisation versus temperature. Ratios of peak areas of γ lines emitted in Sr (1428 keV) and Rb (837 keV) decays are shown. The temperature is decreased from working conditions until the ion currents become very weak. The plateau at low temperature can be understood by the fact that Sr is not ionised anymore and there is no more decease possible. Then, the only contribution to the Sr decay peak is from the decay of Rb collected before transport of the activity to the counting station

  16. RB research nuclear reactor - Annual report for 1986, I - III

    International Nuclear Information System (INIS)

    Markovic, H.; Pesic, M.; Vranic, S.; Petronijevic, M.; Jevremovic, M.; Ilic, I.

    1987-01-01

    This report includes data concerning the RB reactor operation in 1986, state of the reactor components, data about the employed personnel and the database of experimental and other reactor related devices. It is made of 3 parts: Engineering description and operation of the RB reactor including dosimetry, reactor staff data and financial report; Reactor facility components and maintenance; RB reactor operation and utilization in 1986 [sr

  17. Emission spectra of Rb*Hen exciplexes in a cold 4He gas

    International Nuclear Information System (INIS)

    Hirano, K.; Enomoto, K.; Kumakura, M.; Takahashi, Y.; Yabuzaki, T.

    2003-01-01

    We report on the systematic observation of emission spectra of Rb * He n exciplexes (n=1,2,...,6), realized by exciting Rb atoms to the 5 2 P states (Rb * ) in a cold 4 He gas. The observed broad spectral components are assigned to Rb * He n (n=1-6) using theoretical spectra obtained from ab initio potential curves. The dynamics of the exciplex formation is discussed, based on the observed temperature dependence of the spectra. The He gas density dependence of the spectra of Rb * He is understood as a change in the population distribution over the vibrational levels. The present results are compared with our previous work with Cs [K. Enomoto et al., Phys. Rev. A 66, 042505 (2002)], and differences are explained in terms of the difference in the fine-structure splitting. Furthermore, we show the emission spectrum observed after the excitation of Rb in liquid He and conclude that it is the fluorescence from the exciplex Rb * He 6

  18. Crystal structure of 4-RbHo(PO3)4, 4-RbTm(PO3)4 and 4-CsEr(PO3)4

    International Nuclear Information System (INIS)

    Maksimova, S.I.; Palkina, K.K.; Chibiskova, N.T.

    1982-01-01

    X-ray structural study of 4-RbLn(PO 3 ) 4 (Ln=Mo, Tm) and 4-CsEr(PO 3 ) 4 is carried out. The compounds are crystallized in monoclinic crystal system, sp. gr P2 1 /n. Parameters of their unit cell, atom coordinates, anisotropic heat parameters, interatomic distances and valent angles are given. 4-RbHo(PO 3 ) 4 , 4-RbTm(PO 3 ) 4 , 4-CsEr(PO 3 ) 4 are isostructural to previously studied TlNd(PO 3 ) and 4-RbNd(PO 3 ) 4 . Using as an example the structural type 4-M 1 Ln(PO 3 ) 4 it is shown that the change of the shortest distances Ln-Ln, M 1 -M 1 and M 1 -Ln, as well as of degree of polymorphous chain corrugation to a higher extent depends on rare earth atom dimensions, than on monovalent metal ion dimensions [ru

  19. Deregulation of the RB pathway in human testicular germ cell tumours

    DEFF Research Database (Denmark)

    Bartkova, Jirina; Lukas, Claudia; Sørensen, Claus S

    2003-01-01

    Deregulation of the RB pathway is shared by most human malignancies. Components upstream of the retinoblastoma tumour suppressor (pRB), namely the INK4 family of cyclin-dependent kinase (CDK) inhibitors, the D-type cyclins, their partner kinases CDK4/CDK6, and pRB as their critical substrate...

  20. Research Project 'RB research nuclear reactor' (operation and maintenance), Final report; Naucnoistrazivacki projekt 'Istrazivacki nuclearni reaktor RB, (pogon i odrzavanje), Zavrsni elaborat projekta

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1985-07-01

    This final report covers operation and maintenance activities at the RB reactor during period from 1981-1985. First part covers the RB reactor operation, detailed description of reactor components, fuel, heavy water, reactor vessel, cooling system, equipment and instrumentation, auxiliary systems. It contains data concerned with dosimetry and radiation protection, reactor staff, and financial data. Second part deals maintenance, regular control and testing of reactor equipment and instrumentation. Third part is devoted to basic experimental options and utilization of the RB reactor including training.

  1. Exact eigenstates and open-quotes trivialityclose quotes of λ(var-phi *var-phi)2 theory in the Feshbach-Villars formulation

    International Nuclear Information System (INIS)

    Darewych, J.W.

    1997-01-01

    The complex scalar (Klein-Gordon) quantum field theory (QFT) with a λ(var-phi * var-phi) 2 interaction is considered in the Feshbach-Villars formulation. It is shown that exact few-particle eigenstates of the QFT Hamiltonian can be obtained. The resulting relativistic few-body equations correspond to Klein-Gordon particles interacting via delta-function, or open-quotes contact,close quotes potentials. Momentum-space solutions of the two-body equation yield a open-quotes trivialclose quotes unity S matrix. copyright 1997 The American Physical Society

  2. The immunological response of RB51 vaccinated buffalo calves ...

    African Journals Online (AJOL)

    radosova

    2011-09-07

    Sep 7, 2011 ... Consequently, cattle vaccinated with RB51 do not sero- convert on conventional .... 1997), iELISAs using a 5% optical density heat-killed whole RB51 .... In: Yousef MK (Ed.), Stress Physiology in Livestock,. Ungulates, vol. 2.

  3. The Feshbach-Kerman-Koonin multistep reaction theory and its application to data evaluation

    International Nuclear Information System (INIS)

    Hodgson, P.E.; Chadwick, M.B.

    1994-01-01

    The development of the multistep nuclear reaction theory of Feshbach, Kerman, and Koonin (FKK) is reviewed, with particular attention to recent work. We present methodologies for unambiguously separating multistep direct and multistep compound contributions, and analyze neutron inelastic scattering by 93 Nb at 14: MeV to illustrate the approaches. Modification of the FKK theory to include transitions from the multistep direct to the multistep compound chain (''P→Q transitions'') is discussed. We also describe developments to the theory in order to calculate inelastic cross sections for incident nucleon energies to 200 MeV. At these high energies multiple preequilibrium emission processes must be included, and a theory for their determination is described and compared with experimental measurements of proton reactions on 90 Zr. The usefulness of the FKK theory for a range of nuclear data applications, including intermediate energy reactions of importance in Accelerator Transmutation of Waste, reactions on biologically-important elements for cancer radiation treatment, and reactions of importance in fusion technology, is assessed

  4. RB research nuclear reactor, Annual report for 1981

    International Nuclear Information System (INIS)

    Markovic, H.; Sotic, O.; Pesic, M.; Vranic, S.; Zivkovic, B.; Bogdanovic, M.; Petronijevic, M.

    1981-01-01

    The annual report for 1981 includes the following: utilization of the RB reactor; accident and incidents analysis; description of the reactor equipment status; dosimetry and radiation protection; RB reactor staff; financial data. Seven Annexes to this report are concerned with: maintenance of the reactor components and equipment, including nuclear fuel, heavy water, reactor vessel, heavy water coolant circuit, experimental platforms, absorption rods; maintenance of the electric power supply system, neutron source equipment, crane; control and maintenance of ventilation and heating systems, gas and comprised gas systems, fire protection system; plan for renewal of the reactor components; contents of the RB reactor safety report; reactor staff; review of measured radiation doses; experimental methods; training of the staff; and financial report

  5. Optical pumping in a microfabricated Rb vapor cell using a microfabricated Rb discharge light source

    Energy Technology Data Exchange (ETDEWEB)

    Venkatraman, V.; Kang, S.; Affolderbach, C.; Mileti, G., E-mail: gaetano.mileti@unine.ch [Laboratoire Temps-Fréquence, University of Neuchâtel, Neuchâtel 2000 (Switzerland); Shea, H. [Microsystems for Space Technologies Laboratory, Ecole Polytechnique Fédérale de Lausanne (EPFL), Neuchâtel 2002 (Switzerland)

    2014-02-03

    Miniature (Rb discharge lamp light source, as well as (2) a conventional glass-blown Rb discharge lamp. The microfabricated Rb lamp cell is a dielectric barrier discharge (DBD) light source, having the same inner cell volume of around 40 mm{sup 3} as that of the resonance cell, both filled with suitable buffer gases. A miniature (∼2 cm{sup 3} volume) test setup based on the M{sub z} magnetometer interrogation technique was used for observation of optical-radiofrequency double-resonance signals, proving the suitability of the microfabricated discharge lamp to introduce efficient optical pumping. The pumping ability of this light source was found to be comparable to or even better than that of a conventional glass-blown lamp. The reported results indicate that the micro-fabricated DBD discharge lamp has a high potential for the development of a new class of miniature atomic clocks, magnetometers, and quantum sensors.

  6. Spectroscopic properties of the low-lying electronic states of RbHen (n = 1, 2) and their comparison with lighter alkali metal-helium systems

    International Nuclear Information System (INIS)

    Chattopadhyay, Anjan

    2012-01-01

    Ab initio-based configuration interaction studies on RbHe and He–Rb–He have explored some key features of the low-lying electronic states of these van der Waals systems. The radiative lifetime of the Rb*He exciplex has been calculated to be around 24.5 ns, which is slightly higher than the HeRb*He lifetime (∼20 ns) and lower than the atomic fluorescence lifetime of Rb, by roughly 3.5 ns. Better exciplex stability of the symmetric triatomic system is evidenced by its higher binding energy value in comparison to the diatomic system by a substantial margin. BSSE-corrected spin–orbit calculations of RbHe have predicted a potential barrier of the 1 2 Π 1/2 state with a height of 15 cm −1 and width of 2.57 Å. The 2 Π u state of the triatomic molecule shows a conical intersection of its Renner–Teller components (1 2 A 1 and 1 2 B 2 ) near a 99° bond angle along the bending path. Their unstable higher excited states (1 2 Σ + 1/2 or 1 2 Σ + g, 1/2 ) can trigger the pumping of the blue side of the ns 2 S 1/2 → np 2 P 3/2 transition, and this may eventually lead to the np 2 P 1/2 →ns 2 S 1/2 lasing transition. The broad fluorescence band with a peak near 11 900 cm −1 is found to arise from the 1 2 Π 3/2 –X 2 Σ + 1/2 transition of RbHe. (paper)

  7. Intermediate-range chemical ordering of cations in molten RbCl-AgCl

    Energy Technology Data Exchange (ETDEWEB)

    Tahara, S. [Department of Physics and Earth Sciences, Faculty of Science, University of the Ryukyus, Okinawa 903-0213 (Japan); Research and Utilization Division, Japan Synchrotron Radiation Research Institute (JASRI, SPring-8), Hyogo 679-5198 (Japan); Kawakita, Y. [J-PARC Center, Japan Atomic Energy Agency (JAEA), Ibaraki 319-1195 (Japan); Shimakura, H. [Faculty of Pharmacy, Niigata University of Pharmacy and Applied Life Sciences, Niigata 956-8603 (Japan); Ohara, K. [Research and Utilization Division, Japan Synchrotron Radiation Research Institute (JASRI, SPring-8), Hyogo 679-5198 (Japan); Fukami, T. [Department of Physics and Earth Sciences, Faculty of Science, University of the Ryukyus, Okinawa 903-0213 (Japan); Takeda, S. [Department of Physics, Faculty of Sciences, Kyushu University, Fukuoka 812-8581 (Japan)

    2015-07-28

    A first sharp diffraction peak (FSDP) is observed in the X-ray total structure factor of a molten mixture of RbCl-AgCl, while both pure melts of RbCl and AgCl do not exhibit FSDP individually. Molecular dynamics simulations were performed to investigate the origin of the FSDP with the polarizable ion model (PIM). Coexistence of covalent Ag–Cl and ionic Rb–Cl bonds leads the system to evolve intermediate range ordering, which is simulated by introducing the induced polarization in different ways between Ag–Cl with fully polarizable treatment based on Vashishta-Raman potential and Rb–Cl with suppression over-polarization in the nearest neighbor contribution based on Born-Meyer potential. The partial structure factors for both the Ag–Ag and Rb–Rb correlations, S{sub AgAg}(Q) and S{sub RbRb}(Q), show a positive contribution to the FSDP, while S{sub AgRb}(Q) for the Ag–Rb correlation exhibits a negative contribution, indicating that Ag and Rb ions are distributed in an alternating manner within the intermediate-range length scale. The origin of the intermediate-range chemical ordering of cations can be ascribed to the preferred direction of the dipole moments of anions in the PIM.

  8. Immunohistochemical study of p53, pRb, p16 in esophageal cancer

    International Nuclear Information System (INIS)

    Zo, Jae Ill; Zo, Kyung Ja; Park, Jong Ho; Kim, Mi Hee

    1998-01-01

    To confirm the expression of molecular genetic alterations of p53, pRb, p16 in esophageal cancer and to investigate the expression of p53, pRb, p16 in esophageal cancer according to the pathologic steps of carcinogenesis, immuno-histochemistry was performed in 15 resected esophageal cancer specimens with multiple separated lesions after pathologic mapping. The accumulation of mutant p53 was observed in 60 % of dysplasia and 47 % of invasive cancer, while pRb was not detected in 91 % of dysplasia and 72.7 % of invasive cancer. But p16 was not observed in 0 % in dysplasia and 7 % of invasive cancer. But p16 was not observed in 0 % in dysplasia and 28.6 % in invasive cancer. There was no simultaneous negative pRb and p16 expression. There was no relations between p53 and p16, pRb. As a results, the expression of p53, pRb, p16 was co-related well with molecular genetic changes and inactivation of p53, pRb, p16 was co-related well with molecular genetic changes and inactivation of p53 and pRb was common and early event in esophageal carcinogenesis in Korea, but inactivation of p16 was a infrequent change. (author). 17 refs., 2 tabs., 7 figs

  9. Intermediate-range chemical ordering of cations in molten RbCl-AgCl

    International Nuclear Information System (INIS)

    Tahara, S.; Kawakita, Y.; Shimakura, H.; Ohara, K.; Fukami, T.; Takeda, S.

    2015-01-01

    A first sharp diffraction peak (FSDP) is observed in the X-ray total structure factor of a molten mixture of RbCl-AgCl, while both pure melts of RbCl and AgCl do not exhibit FSDP individually. Molecular dynamics simulations were performed to investigate the origin of the FSDP with the polarizable ion model (PIM). Coexistence of covalent Ag–Cl and ionic Rb–Cl bonds leads the system to evolve intermediate range ordering, which is simulated by introducing the induced polarization in different ways between Ag–Cl with fully polarizable treatment based on Vashishta-Raman potential and Rb–Cl with suppression over-polarization in the nearest neighbor contribution based on Born-Meyer potential. The partial structure factors for both the Ag–Ag and Rb–Rb correlations, S AgAg (Q) and S RbRb (Q), show a positive contribution to the FSDP, while S AgRb (Q) for the Ag–Rb correlation exhibits a negative contribution, indicating that Ag and Rb ions are distributed in an alternating manner within the intermediate-range length scale. The origin of the intermediate-range chemical ordering of cations can be ascribed to the preferred direction of the dipole moments of anions in the PIM

  10. RbCuFe(PO42

    Directory of Open Access Journals (Sweden)

    Mongi Ben Amara

    2013-08-01

    Full Text Available A new iron phosphate, rubidium copper(II iron(III bis(phosphate, RbCuFe(PO42, has been synthesized as single crystals by the flux method. This compound is isostructural with KCuFe(PO42 [Badri et al. (2011, J. Solid State Chem. 184, 937–944]. Its structure is built up from Cu2O8 units of edge-sharing CuO5 polyhedra, interconnected by FeO6 octahedra through common corners to form undulating chains that extend infinitely along the [011] and [01-1] directions. The linkage of such chains is ensured by the PO4 tetraedra and the resulting three-dimensional framework forms quasi-elliptic tunnels parallel to the [101] direction in which the Rb+ cations are located.

  11. One-dimensional gas of bosons with Feshbach-resonant interactions

    International Nuclear Information System (INIS)

    Gurarie, V.

    2006-01-01

    We present a study of a gas of bosons confined in one dimension with Feshbach-resonant interactions, at zero temperature. Unlike the gas of one-dimensional bosons with non resonant interactions, which is known to be equivalent to a system of interacting spinless fermions and can be described using the Luttinger liquid formalism, the resonant gas possesses additional features. Depending on its parameters, the gas can be in one of three possible regimes. In the simplest of those, it can still be described by the Luttinger liquid theory, but its Fermi momentum cannot be larger than a certain cutoff momentum dependent on the details of the interactions. In the other two regimes, it is equivalent to a Luttinger liquid at low density only. At higher densities its excitation spectrum develops a minimum, similar to the roton minimum in helium, at momenta where the excitations are in resonance with the Fermi sea. As the density of the gas is increased further, the minimum dips below the Fermi energy, thus making the ground state unstable. At this point the standard ground state gets replaced by a more complicated one, where not only the states with momentum below the Fermi points, but also the ones with momentum close to that minimum, get filled, and the excitation spectrum develops several branches. We are unable so far to study this regime in detail due to the lack of the appropriate formalism

  12. CENPA overexpression promotes genome instability in pRb-depleted human cells

    Directory of Open Access Journals (Sweden)

    Lentini Laura

    2009-12-01

    Full Text Available Abstract Background Aneuploidy is a hallmark of most human cancers that arises as a consequence of chromosomal instability and it is frequently associated with centrosome amplification. Functional inactivation of the Retinoblastoma protein (pRb has been indicated as a cause promoting chromosomal instability as well centrosome amplification. However, the underlying molecular mechanism still remains to be clarified. Results Here we show that pRb depletion both in wild type and p53 knockout HCT116 cells was associated with the presence of multipolar spindles, anaphase bridges, lagging chromosomes and micronuclei harbouring whole chromosomes. In addition aneuploidy caused by pRb acute loss was not affected by p53 loss. Quantitative real-time RT-PCR showed that pRB depletion altered expression of genes involved in centrosome duplication, kinetochore assembly and in the Spindle Assembly Checkpoint (SAC. However, despite MAD2 up-regulation pRb-depleted cells seemed to have a functional SAC since they arrested in mitosis after treatments with mitotic poisons. Moreover pRb-depleted HCT116 cells showed BRCA1 overexpression that seemed responsible for MAD2 up-regulation. Post-transcriptional silencing of CENPA by RNA interference, resulting in CENP-A protein levels similar to those present in control cells greatly reduced aneuploid cell numbers in pRb-depleted cells. Conclusion Altogether our findings indicate a novel aspect of pRb acute loss that promotes aneuploidy mainly by inducing CENPA overexpression that in turn might induce micronuclei by affecting the correct attachment of spindle microtubules to kinetochores.

  13. Evodiamine selectively targets cancer stem-like cells through the p53-p21-Rb pathway

    International Nuclear Information System (INIS)

    Han, Seula; Woo, Jong Kyu; Jung, Yuchae; Jeong, Dawoon; Kang, Minsook; Yoo, Young-Ji; Lee, Hani; Oh, Seung Hyun; Ryu, Jae-Ha; Kim, Woo-Young

    2016-01-01

    In spite of the recent improvements, the resistance to chemotherapy/radiotherapy followed by relapse is the main hurdle for the successful treatment of breast cancer, a leading cause of death in women. A small population of breast cancer cells that have stem-like characteristics (cancer stem-like cells; CSLC) may contribute to this resistance and relapse. Here, we report on a component of a traditional Chinese medicine, evodiamine, which selectively targets CSLC of breast cancer cell lines MCF7 and MDAMB 231 at a concentration that does show a little or no cytotoxic effect on bulk cancer cells. While evodiamine caused the accumulation of bulk cancer cells at the G2/M phase, it did not hold CSLC in a specific cell cycle phase but instead, selectively killed CSLC. This was not due to the culture of CSLC in suspension or without FBS. A proteomic analysis and western blotting revealed that evodiamine changed the expression of cell cycle regulating molecules more efficiently in CSLC cells than in bulk cancer cells. Surprisingly, evodiamine selectively activated p53 and p21 and decreased inactive Rb, the master molecules in G1/S checkpoint. These data collectively suggest a novel mechanism involving CSLC-specific targeting by evodiamine and its possible use to the therapy of breast cancer. - Highlights: • Evodiamine selectively kills breast cancer stem like cells at G1 phase. • Evodiamine utilizes different mechanism of cell cycle modulation in CSLC and in bulk cancer cells. • Evodiamine activate the p53, p21 and Rb pathway.

  14. Evodiamine selectively targets cancer stem-like cells through the p53-p21-Rb pathway

    Energy Technology Data Exchange (ETDEWEB)

    Han, Seula [The Research Center for Cell Fate Control, College of Pharmacy, Sookmyung Women' s University, Seoul (Korea, Republic of); Woo, Jong Kyu [College of Pharmacy, Gachon University, Incheon (Korea, Republic of); Jung, Yuchae; Jeong, Dawoon; Kang, Minsook; Yoo, Young-Ji; Lee, Hani [The Research Center for Cell Fate Control, College of Pharmacy, Sookmyung Women' s University, Seoul (Korea, Republic of); Oh, Seung Hyun [College of Pharmacy, Gachon University, Incheon (Korea, Republic of); Ryu, Jae-Ha [The Research Center for Cell Fate Control, College of Pharmacy, Sookmyung Women' s University, Seoul (Korea, Republic of); Kim, Woo-Young, E-mail: wykim@sookmyung.ac.kr [The Research Center for Cell Fate Control, College of Pharmacy, Sookmyung Women' s University, Seoul (Korea, Republic of)

    2016-01-22

    In spite of the recent improvements, the resistance to chemotherapy/radiotherapy followed by relapse is the main hurdle for the successful treatment of breast cancer, a leading cause of death in women. A small population of breast cancer cells that have stem-like characteristics (cancer stem-like cells; CSLC) may contribute to this resistance and relapse. Here, we report on a component of a traditional Chinese medicine, evodiamine, which selectively targets CSLC of breast cancer cell lines MCF7 and MDAMB 231 at a concentration that does show a little or no cytotoxic effect on bulk cancer cells. While evodiamine caused the accumulation of bulk cancer cells at the G2/M phase, it did not hold CSLC in a specific cell cycle phase but instead, selectively killed CSLC. This was not due to the culture of CSLC in suspension or without FBS. A proteomic analysis and western blotting revealed that evodiamine changed the expression of cell cycle regulating molecules more efficiently in CSLC cells than in bulk cancer cells. Surprisingly, evodiamine selectively activated p53 and p21 and decreased inactive Rb, the master molecules in G1/S checkpoint. These data collectively suggest a novel mechanism involving CSLC-specific targeting by evodiamine and its possible use to the therapy of breast cancer. - Highlights: • Evodiamine selectively kills breast cancer stem like cells at G1 phase. • Evodiamine utilizes different mechanism of cell cycle modulation in CSLC and in bulk cancer cells. • Evodiamine activate the p53, p21 and Rb pathway.

  15. He 3 -Xe 129 Comagnetometery using Rb 87 Detection and Decoupling

    Science.gov (United States)

    Limes, M. E.; Sheng, D.; Romalis, M. V.

    2018-01-01

    We describe a He 3 -Xe 129 comagnetometer using Rb 87 atoms for noble-gas spin polarization and detection. We use a train of Rb 87 π pulses and σ+/σ- optical pumping to realize a finite-field Rb magnetometer with suppression of spin-exchange relaxation. We suppress frequency shifts from polarized Rb by measuring the He 3 and Xe 129 spin precession frequencies in the dark, while applying π pulses along two directions to depolarize Rb atoms. The plane of the π pulses is rotated to suppress the Bloch-Siegert shifts for the nuclear spins. We measure the ratio of He 3 to Xe 129 spin precession frequencies with sufficient absolute accuracy to resolve Earth's rotation without changing the orientation of the comagnetometer. A frequency resolution of 7 nHz is achieved after integration for 8 h without evidence of significant drift.

  16. Rb-intercalated C60 compounds studied by Inverse Photoemission Spectroscopy

    International Nuclear Information System (INIS)

    Finazzi, M.; Brambilla, A; Biagioni, P.; Cattoni, A.; Duo, L.; Ciccacci, F.; Braicovich, L.; Giovanelli, L.; Goldoni, A.

    2004-01-01

    Full text: Since the discovery of superconductivity in alkali-doped solid C 60 , the electronic structure of the host material (C 60 ) and the doped compounds (A x C 60 , where A is an alkali metal), has been the subject of a considerable amount of work, both theoretical and experimental. The spectroscopic investigations of the alkali-doped C 60 compounds has been mainly focussed on the valence states, while much less information is available on the unoccupied states. In particular, inverse photoemission data on the complete set of stable Rb x C 60 compounds was, so far, still missing. We have performed Inverse Photoemission (IPE) spectroscopy on Rb x C 60 compounds (x = 1, 3, 4, 6). IPE spectra were obtained using a band-pass photon detector (hv = 9.4 eV, FWHM = 0.7 eV) and scanning the kinetic energy of the electrons impinging on the sample. Rb was evaporated on C 60 films (thickness = 6-12 atomic layers) grown in situ on a Cu(100) substrate. The temperature of the substrate was kept equal to T = 100 deg C, which is lower than the C 60 sublimation temperature. The amount of Rb was checked by measuring the intensity of the C1s and Rb3d photoemission lines. After the required amount of Rb had been deposited, the samples were annealed to distillate the desired stable phase

  17. Pump-probe study of the formation of rubidium molecules by ultrafast photoassociation of ultracold atoms

    Science.gov (United States)

    McCabe, David J.; England, Duncan G.; Martay, Hugo E. L.; Friedman, Melissa E.; Petrovic, Jovana; Dimova, Emiliya; Chatel, Béatrice; Walmsley, Ian A.

    2009-09-01

    An experimental pump-probe study of the photoassociative creation of translationally ultracold rubidium molecules is presented together with numerical simulations of the process. The formation of loosely bound excited-state dimers is observed as a first step toward a fully coherent pump-dump approach to the stabilization of Rb2 into its lowest ground vibrational states. The population that contributes to the pump-probe process is characterized and found to be distinct from a background population of preassociated molecules.

  18. ATM/RB1 mutations predict shorter overall survival in urothelial cancer.

    Science.gov (United States)

    Yin, Ming; Grivas, Petros; Emamekhoo, Hamid; Mendiratta, Prateek; Ali, Siraj; Hsu, JoAnn; Vasekar, Monali; Drabick, Joseph J; Pal, Sumanta; Joshi, Monika

    2018-03-30

    Mutations of DNA repair genes, e.g. ATM/RB1 , are frequently found in urothelial cancer (UC) and have been associated with better response to cisplatin-based chemotherapy. Further external validation of the prognostic value of ATM/RB1 mutations in UC can inform clinical decision making and trial designs. In the discovery dataset, ATM/RB1 mutations were present in 24% of patients and were associated with shorter OS (adjusted HR 2.67, 95% CI, 1.45-4.92, p = 0.002). There was a higher mutation load in patients carrying ATM/RB1 mutations (median mutation load: 6.7 versus 5.5 per Mb, p = 0.072). In the validation dataset, ATM/RB1 mutations were present in 22.2% of patients and were non-significantly associated with shorter OS (adjusted HR 1.87, 95% CI, 0.97-3.59, p = 0.06) and higher mutation load (median mutation load: 8.1 versus 7.2 per Mb, p = 0.126). Exome sequencing data of 130 bladder UC patients from The Cancer Genome Atlas (TCGA) dataset were analyzed as a discovery cohort to determine the prognostic value of ATM/RB1 mutations. Results were validated in an independent cohort of 81 advanced UC patients. Cox proportional hazard regression analysis was performed to calculate the hazard ratio (HR) and 95% confidence interval (CI) to compare overall survival (OS). ATM/RB1 mutations may be a biomarker of poor prognosis in unselected UC patients and may correlate with higher mutational load. Further studies are required to determine factors that can further stratify prognosis and evaluate predictive role of ATM/RB1 mutation status to immunotherapy and platinum-based chemotherapy.

  19. Study of positive-parity yrast band in 83Rb

    International Nuclear Information System (INIS)

    Ganguly, S.; Banerjee, P.; Ray, I.; Kshetri, R.; Bhattacharya, S.; Saha Sarkar, M.; Goswami, A.; Muralithar, S.; Singh, R.P.; Kumar, R.; Bhowmik, R.K.

    2005-01-01

    The properties of the positive-parity yrast band in the odd-A 81,83,85 Rb (Z=37) isotopes show remarkable changes as N increases. The objective of the present work is to study the structure of the lowest positive-parity band in 83 Rb from lifetime studies

  20. Microbial conversion of major ginsenoside Rb1 to minor ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-12-15

    Dec 15, 2009 ... minor ginsenoside Rd by Indian fermented food bacteria. Kalaiselvi ... South Korea. Accepted 17 April, 2009. Ginsenoside Rb1 is the predominant secondary metabolite (saponin) in Panax ginseng. Hydrolysis of the sugar .... culture and 200 µl of major ginsenoside Rb1. The reaction mixture was incubated ...

  1. Ginsenoside Rb1 Protects Rat Neural Progenitor Cells against Oxidative Injury

    Directory of Open Access Journals (Sweden)

    Na Ni

    2014-03-01

    Full Text Available Ginseng, the root of Panax ginseng C.A. Meyer, has been used as a tonic to enhance bodily functions against various ailments for hundreds of years in Far Eastern countries without apparent adverse effects. Ginsenoside Rb1, one of the most active ingredients of ginseng, has been shown to possess various pharmacological activities. Here we report that Rb1 exhibits potent neuroprotective effects against oxidative injury induced by tert-butylhydroperoxide (t-BHP. Lactate dehydrogenase (LDH assay demonstrated that incubation with 300 µm t-BHP for 2.5 h led to a significant cell loss of cultured rat embryonic cortex-derived neural progenitor cells (NPCs and the cell viability was pronouncedly increased by 24 h pretreatment of 10 µm Rb1. TUNEL staining further confirmed that pretreatment of Rb1 significantly reduced the cell apoptosis in t-BHP-induced oxidative injury. Real time PCR revealed that pretreatment with Rb1 activated Nrf2 pathway in cultured NPCs and led to an elevated expression of HO-1. The results of the present study demonstrate that Rb1 shows a potent anti-oxidative effect on cultured NPCs by activating Nrf2 pathway.

  2. Dissociation Energies of Diatomic Molecules

    International Nuclear Information System (INIS)

    Qun-Chao, Fan; Wei-Guo, Sun

    2008-01-01

    Molecular dissociation energies of 10 electronic states of alkali molecules of KH, 7 LiD, 7 LiH, 6 LiH, NaK, NaLi and NaRb are studied using the highest three accurate vibrational energies of each electronic state, and an improved parameter-free analytical formula which is obtained starting from the LeRoy–Bernstein vibrational energy expression near the dissociation limit. The results show that as long as the highest three vibrational energies are accurate, the current analytical formula will give accurate theoretical dissociation energies D e theory , which are in excellent agreement with the experimental dissociation energies D e expt . (atomic and molecular physics)

  3. The Rb-Sr system

    International Nuclear Information System (INIS)

    Graham, I.J.

    1983-11-01

    This manual is intended to serve as a guide to the chemical procedures involved in Rb-Sr isotopic analysis as conducted at the Institute of Nuclear Sciences. Included are notes on the experimental developments made over the last 2.5 years, especially those involving rock dissolution and cation exchange chromatography

  4. The Re-evaluation of 84Rb decay data

    International Nuclear Information System (INIS)

    Huang Xiaolong; Zhou Chunmei

    1996-01-01

    The 84 Rb is an important radionuclide and its decay data are fundamental data in nuclear applications. The decay data for 84 Rb were re-evaluated. The energies and intensities of γ rays and their internal conversion coefficients, energies and intensities of Auger electrons, conversion electrons and x-rays, were recommended. The decay scheme was also given. The balance of radiation rays intensities and energies was checked. (9 tabs., 2 figs.)

  5. The Neural Cell Adhesion Molecule NCAM2/OCAM/RNCAM, a Close Relative to NCAM

    DEFF Research Database (Denmark)

    Kulahin, Nikolaj; Walmod, Peter

    2008-01-01

    molecule (NCAM) is a well characterized, ubiquitously expressed CAM that is highly expressed in the nervous system. In addition to mediating cell adhesion, NCAM participates in a multitude of cellular events, including survival, migration, and differentiation of cells, outgrowth of neurites, and formation......Cell adhesion molecules (CAMs) constitute a large class of plasma membrane-anchored proteins that mediate attachment between neighboring cells and between cells and the surrounding extracellular matrix (ECM). However, CAMs are more than simple mediators of cell adhesion. The neural cell adhesion...... and plasticity of synapses. NCAM shares an overall sequence identity of approximately 44% with the neural cell adhesion molecule 2 (NCAM2), a protein also known as olfactory cell adhesion molecule (OCAM) and Rb-8 neural cell adhesion molecule (RNCAM), and the region-for-region sequence homology between the two...

  6. Rb-Sr dating of sphalerites from Mississippi Valley-type (MVT) ore deposits

    Energy Technology Data Exchange (ETDEWEB)

    Nakai, S.; Halliday, A.N.; Kesler, S.E.; Jones, H.D. (Univ. of Michigan, Ann Arbor (United States)); Kyle, J.R. (Univ. of Texas, Austin (United States)); Lane, T.E. (Memorial Univ. of Newfoundland, St. John' s (Canada))

    1993-01-01

    Mississippi Valley-type (MVT) ore deposits are epigenetic carbonate-hosted Pb-Zn deposits that contain galena, sphalerite, fluorite, barite, dolomite, calcite, and quartz. Although they are thought to form from basinal brines, their exact origins are still unclear, partly because of the scarcity of reliable geochronological data. Rb-Sr dating of sphalerites has recently been shown to be a promising technique for the direct dating of ore minerals in MVT deposits. This paper reports the results of a reconnaissance study of sphalerites, their fluid inclusions, and associated minerals from MVT deposits of North America. Sphalerites from Immel mine, Mascot-Jefferson City district, east Tennessee, define a Rb-Sr age of 347 [plus minus] 20 Ma consistent with a Rb-Sr age of 377 [plus minus] 29 Ma for sphalerites from Coy mine in the same district, but inconsistent with models that ascribe their genesis to the effects of the late Paleozoic Alleghenian orogeny. Rb-Sr isotopic analyses of K-feldspar from Immel mine preclude the possibility that the Rb-Sr data reflect feldspar inclusions. Sphalerites from the main ore zone of Daniel's Harbour mine, Newfoundland, do not form a linear isochron and open behavior of the Rb-Sr system is suspected. Sphalerites from the Pine Point district, Northwest Territories, Canada, define a Rb-Sr age of 361 [plus minus] 13 Ma, indicating that the mineralization took place shortly after the deposition of the middle Devonian host carbonate rocks. These results are not compatible with mineralization models based on regional fluid migration related to early Tertiary Cordilleran deformation. Sphalerites from northern Arkansas have very low Rb and Sr concentrations (less than 0.1 ppm). The Rb-Sr data do not form isochrons and the sphalerites have higher [sup 87]Sr/[sup 86]Sr ratios than expected, given their Rb/Sr ratios and reasonable constraints on their ages. 58 refs., 7 figs., 2 tabs.

  7. 50 years of the RB reactor utilization

    International Nuclear Information System (INIS)

    Milosevic, M.; Pesic, M.; Ljubenov, V.

    2008-01-01

    This paper is dedicated to the 50 th anniversary of the RB reactor operation, which was the first nuclear reactor built in former Yugoslavia. Information about the construction period, basic technical characteristics and experimental possibilities of the facility, description of first experiments performed 50 years ago, utilisation and modifications done during the implementation of different state nuclear programs and the most important research results are presented in the paper. Role of the RB reactor in the forthcoming decommissioning of the RA research reactor and some plans for future utilisation are underlined also. (author)

  8. Feshbach Resonance due to Coherent {lambda}-{sigma} Coupling in {sup 7}{sub {lambda}}He

    Energy Technology Data Exchange (ETDEWEB)

    Mon, San San; Nwe, Tin Tin [Department of Physics, Mandalay University (Myanmar); Myint, Khin Swe [Pro-Rector, Mandalay University (Myanmar)], E-mail: pro-rector@mptmail.net.mm; Akaishi, Y. [College of Science and Technology, Nihon University, Chiba, Japan and RIKEN Nishina Center, Saitama (Japan)

    2010-04-01

    Coherent {lambda}-{sigma} coupling effect in {sup 7}{sub {lambda}}He is analyzed within three-body framework of two coupled channels, {lambda}-t-t and {sigma}-{tau}-t, where {tau} represents trinulceon which is either {sup 3}H or {sup 3}He. The hyperon-trinucleon (Y{tau}) and trinucleon-trinucleon ({tau}{tau}) interactions are derived by folding G-matrices of YN and NN interactions with trinucleon density distributions. It is found that the binding energy of {sup 7}{sub {lambda}}He is 4.04 MeV below the {lambda}+t+t threshold without {lambda}-{sigma} coupling and the binding energy is increased to 4.46 MeV when the coupling effect is included. This state is 7.85 MeV above the {sup 6}He+{lambda} threshold and it may have a chance to be observed as a Feshbach resonance in {sup 7}Li (e,e{sup '}K{sup +}){sup 7}{sub {lambda}}He experiment done at Jefferson Lab.

  9. Decay of84fRb

    International Nuclear Information System (INIS)

    Passaro, A.M.P.

    1987-01-01

    For the first time, low intensity beta ramifications were determined in the decay of 84 Rb to 84 Kr. The methodology and apparatus employed are presented as well as the advantages and experimental array. (A.C.A.S.) [pt

  10. Herbarium collection of the Rio de Janeiro Botanical Garden (RB), Brazil.

    Science.gov (United States)

    Lanna, João M; da Silva, Luís Alexandre E; Morim, Marli P; Leitman, Paula M; Queiroz, Natália O; Filardi, Fabiana L R; Dalcin, Eduardo C; Oliveira, Felipe A; Forzza, Rafaela C

    2018-01-01

    This paper provides a quantitative and general description of the Rio de Janeiro Botanical Garden herbarium (RB) dataset. Created over a century ago, the RB currently comprises ca. 750,000 mounted specimens, with a strong representation of Brazilian flora, mainly from the Atlantic and Amazon forests. Nearly 100% of these specimens have been entered into the database and imaged and, at present, about 17% have been geo-referenced. This data paper is focused exclusively on RB's exsiccatae collection of land plants and algae, which is currently increasing by about twenty to thirty thousand specimens per year thanks to fieldwork, exchange and donations. Since 2005, many national and international projects have been implemented, improving the quality and accessibility of the collection. The most important facilitating factor in this process was the creation of the institutional system for plants collection and management, named JABOT. Since the RB is continuously growing, the dataset is updated weekly on SiBBr and GBIF portals. The most represented environments are the Atlantic and Amazon forests, a biodiversity hotspot and the world's largest rain forest, respectively. The dataset described in this article contains the data and metadata of plants and algae specimens in the RB collection and the link to access the respective images. Currently, the RB data is publicly available online at several biodiversity portals, such as our institutional database JABOT, the Reflora Virtual Herbarium, the SiBBr and the GBIF portal. However, a description of the RB dataset as a whole is not available in the literature.

  11. Herbarium collection of the Rio de Janeiro Botanical Garden (RB), Brazil

    Science.gov (United States)

    da Silva, Luís Alexandre E; Morim, Marli P.; Leitman, Paula M.; Queiroz, Natália O.; Filardi, Fabiana L. R.; Dalcin, Eduardo C.; Oliveira, Felipe A.

    2018-01-01

    Abstract Background This paper provides a quantitative and general description of the Rio de Janeiro Botanical Garden herbarium (RB) dataset. Created over a century ago, the RB currently comprises ca. 750,000 mounted specimens, with a strong representation of Brazilian flora, mainly from the Atlantic and Amazon forests. Nearly 100% of these specimens have been entered into the database and imaged and, at present, about 17% have been geo-referenced. This data paper is focused exclusively on RB's exsiccatae collection of land plants and algae, which is currently increasing by about twenty to thirty thousand specimens per year thanks to fieldwork, exchange and donations. Since 2005, many national and international projects have been implemented, improving the quality and accessibility of the collection. The most important facilitating factor in this process was the creation of the institutional system for plants collection and management, named JABOT. Since the RB is continuously growing, the dataset is updated weekly on SiBBr and GBIF portals. New information The most represented environments are the Atlantic and Amazon forests, a biodiversity hotspot and the world's largest rain forest, respectively. The dataset described in this article contains the data and metadata of plants and algae specimens in the RB collection and the link to access the respective images. Currently, the RB data is publicly available online at several biodiversity portals, such as our institutional database JABOT, the Reflora Virtual Herbarium, the SiBBr and the GBIF portal. However, a description of the RB dataset as a whole is not available in the literature. PMID:29674937

  12. Relative volatility of dilute solutions of Rb-Cs system

    International Nuclear Information System (INIS)

    Gromov, P.B.; Izotov, V.P.; Nisel'son, L.A.

    1984-01-01

    Relative volatility of diluted solutions Rb-Cs in the temperature range 650-820 K and pressures 13-200 gPa has been studied. The system Rb-Cs in the range of diluted solutions obeys the Henry law. It is shown, that liquid-vapour equilibrium in diluted solutions of cesium in rubidium is characterized by negative deviation from perfection

  13. Use of ionic model for analysis of intramolecular movement in alkali metal metaborate molecules

    International Nuclear Information System (INIS)

    Ezhov, Yu.S.; Vinogradov, V.S.

    1978-01-01

    To clear out the peculiarities of intramolecular movement in MBO 2 (where M=Li, Na, K, Rb, Cs) molecules the energy dependence of cation electrostatic interaction with BO 2 anion on the charge value of oxygen, values of the MOB valence angle and internuclear distance r(M-O) is calculated. The calculation results on the base of ionic model show that the minimum of potential energy function corresponds to angular configuration of the MBO 2 molecules. Parameters of potential function of deformation oscillation connected with the change of MOB angle, are evaluated

  14. Review of accident analyses of RB experimental reactor

    International Nuclear Information System (INIS)

    Pesic, M.

    2003-01-01

    The RB reactor is a uranium fuel heavy water moderated critical assembly that has been put and kept in operation by the VINCA Institute of Nuclear Sciences, Belgrade, Serbia and Montenegro, since April 1958. The first complete Safety Analysis Report of the RB reactor was prepared in 1961/62; yet, the first accident analysis had been made in late 1958 with the aim to examine a power transition and the total equivalent doses received by the staff during the reactivity accident that occurred on October 15, 1958. Since 1960, the RB reactor has been modified a few times. Beside the initial natural uranium metal fuel rods, new types of fuel (TVR-S types of Russian origin) consisting of 2% enriched uranium metal and 80% enriched U0 2 , dispersed in aluminum matrix, have been available since 1962 and 1976, respectively. Modifications of the control and safety systems of the reactor were made occasionally. Special reactor cores were designed and constructed using all three types of fuel elements, as well as the coupled fast-thermal ones. The Nuclear Safety Committee of the VINCA Institute, an independent regulator)' body, approved for usage all these modifications of the RB reactor on the basis of the Preliminary Safety' Analysis Reports, which, beside proposed technical modifications and new regulation rules, included safety analyses of various possible accidents. A special attention was given (and a new safety methodology was proposed) to thorough analyses of the design-based accidents related to the coupled fast-thermal cores that included central zones of the reactor filled by the fuel elements without any moderator. In this paper, an overview of some accidents, methodologies and computation tools used for the accident analyses of the RB reactor is given. (author)

  15. Some Examples of Accident Analyses for RB Reactor

    International Nuclear Information System (INIS)

    Pesic, M.

    2002-01-01

    The RB reactor is heavy water critical assembly operated in the Vinca Institute of Nuclear Sciences, Belgrade, Yugoslavia, since April 1959. The first Safety Analysis Report of the RB critical assembly was prepared in 1961/62. But, the first accidental analysis was done in late 1958 in aim the examine power transient and total equivalent doses received by the staff during the reactivity accident occurred on October 15, 1958. Since 1960, the RB reactor is modified few times. Beside initial natural uranium metal fuel rods, new fuel (TVR-S types) from 2% enriched metal uranium and 80% enriched UO 2 were available since 1962 and 1976, respectively. Also, modifications in control and safety systems of the reactor were done occasionally. Special reactor cores were created using all three types of fuel elements, among them, the coupled fast-thermal ones. Nuclear Safety Committee of the Vinca Institute, an independent regulatory body approved for usage all these modifications of the RB reactor. For those decisions of the Committee, the Preliminary Safety Analysis Reports were prepared that, beside proposed technical modifications and new regulation rules had included analyses of various possible accidents. Special attention is given and new methodology was proposed for thoroughly analyses of design based accidents related to coupled fast-thermal cores, that include reactor central zones filled by fuel elements without moderator. In these accidents, during assumed flooding of the fast zone by moderator, a very high reactivity could be inserted in the system with very high reactivity rate. It was necessary to provide that the safety system of the reactor had fast response to that accident and had enough high (negative) reactivity to shut down the reactor timely. In this paper, a brief overview of some accidents, methodology and computation tools used for the accident analyses at RB reactor are given. (author)

  16. Review of accident analyses of RB experimental reactor

    Directory of Open Access Journals (Sweden)

    Pešić Milan P.

    2003-01-01

    Full Text Available The RB reactor is a uranium fuel heavy water moderated critical assembly that has been put and kept in operation by the VTNCA Institute of Nuclear Sciences, Belgrade, Serbia and Montenegro, since April 1958. The first complete Safety Analysis Report of the RB reactor was prepared in 1961/62 yet, the first accident analysis had been made in late 1958 with the aim to examine a power transition and the total equivalent doses received by the staff during the reactivity accident that occurred on October 15, 1958. Since 1960, the RB reactor has been modified a few times. Beside the initial natural uranium metal fuel rods, new types of fuel (TVR-S types of Russian origin consisting of 2% enriched uranium metal and 80% enriched UO2 dispersed in aluminum matrix, have been available since 1962 and 1976 respectively. Modifications of the control and safety systems of the reactor were made occasionally. Special reactor cores were designed and constructed using all three types of fuel elements as well as the coupled fast-thermal ones. The Nuclear Safety Committee of the VINĆA Institute, an independent regulatory body, approved for usage all these modifications of the RB reactor on the basis of the Preliminary Safety Analysis Reports, which, beside proposed technical modifications and new regulation rules, included safety analyses of various possible accidents. A special attention was given (and a new safety methodology was proposed to thorough analyses of the design-based accidents related to the coupled fast-thermal cores that included central zones of the reactor filled by the fuel elements without any moderator. In this paper, an overview of some accidents, methodologies and computation tools used for the accident analyses of the RB reactor is given.

  17. Low-dose myocardial blood flow imaging using 82Rb-PET (RUBILOW 2.0)

    DEFF Research Database (Denmark)

    Hoff, Camilla Molich; Tolbod, Lars Poulsen; Harms, Hans

    2017-01-01

    Aim: Relative and absolute measures of myocardial blood flow (MBF) can be derived from a 82Rb PET/CT scan using list mode data to extract static, gated and dynamic PET series. High doses of 82Rb are used to maximize image quality in especially static images. High doses require large eluate volumes......, may degrade scanner dead time performance at first pass and decreases generator lifetime. Lower doses will expand the availability of 82Rb PET/CT and lower doses to personnel and patients. The aim of the current study was to examine MBF with a low dose (LD) 82Rb protocol compared to the institution......’s standard (STD) protocol. Methods: Twenty-one patients referred to 82Rb PET were included in the study. Patients were examined during rest and stress with repeated LD (740 MBq) and STD dose (1110 MBq) Rb-PET during the same imaging session. Regional and global rest and stress MBF values, total perfusion...

  18. Accurate 3He polarimetry using the Rb Zeeman frequency shift due to the Rb-3He spin-exchange collisions

    International Nuclear Information System (INIS)

    Romalis, M.V.; Cates, G.D.

    1998-01-01

    We describe a method of 3 He polarimetry relying on the polarization-dependent frequency shift of the Rb Zeeman resonance. Our method is ideally suited for on-line measurements of the 3 He polarization produced by spin-exchange optical pumping. To calibrate the frequency shift we performed an accurate measurement of the imaginary part of the Rb- 3 He spin-exchange cross section in the temperature range typical for spin-exchange optical pumping of 3 He. We also present a detailed study of possible systematic errors in the frequency shift polarimetry. copyright 1998 The American Physical Society

  19. A measurement of Rb using mutually exclusive tags

    Science.gov (United States)

    Barate, R.; Buskulic, D.; Decamp, D.; Ghez, P.; Goy, C.; Lees, J.-P.; Lucotte, A.; Minard, M.-N.; Nief, J.-Y.; Pietrzyk, B.; Casado, M. P.; Chmeissani, M.; Comas, P.; Crespo, J. M.; Delfino, M.; Fernandez, E.; Fernandez-Bosman, M.; Garrido, Ll.; Juste, A.; Martinez, M.; Miquel, R.; Mir, Ll. M.; Orteu, S.; Padilla, C.; Park, I. C.; Pascual, A.; Perlas, J. A.; Riu, I.; Sanchez, F.; Teubert, F.; Colaleo, A.; Creanza, D.; de Palma, M.; Gelao, G.; Iaselli, G.; Maggi, G.; Maggi, M.; Marinelli, N.; Nuzzo, S.; Ranieri, A.; Raso, G.; Ruggieri, F.; Selvaggi, G.; Silvestris, L.; Tempesta, P.; Tricomi, A.; Zito, G.; Huang, X.; Lin, J.; Ouyang, Q.; Wang, T.; Xie, Y.; Xu, R.; Xue, S.; Zhang, J.; Zhang, L.; Zhao, W.; Abbaneo, D.; Alemany, R.; Becker, U.; Bazarko, A. O.; Bright-Thomas, P.; Cattaneo, M.; Cerutti, F.; Drevermann, H.; Forty, R. W.; Frank, M.; Hagelberg, R.; Harvey, J.; Janot, P.; Jost, B.; Kneringer, E.; Knobloch, J.; Lehraus, I.; Lutters, G.; Mato, P.; Minten, A.; Moneta, L.; Pacheco, A.; Pusztaszeri, J.-F.; Ranjard, F.; Rensing, P.; Rizzo, G.; Rolandi, L.; Schlatter, D.; Schmitt, M.; Schneider, O.; Tejessy, W.; Tomalin, I. R.; Wachsmuth, H.; Wagner, A.; Ajaltouni, Z.; Barrès, A.; Boyer, C.; Falvard, A.; Ferdi, C.; Gay, P.; Guicheney, C.; Henrard, P.; Jousset, J.; Michel, B.; Monteil, S.; Montret, J.-C.; Pallin, D.; Perret, P.; Podlyski, F.; Proriol, J.; Rosnet, P.; Rossignol, J.-M.; Fearnley, T.; Hansen, J. B.; Hansen, J. D.; Hansen, J. R.; Hansen, P. H.; Nilsson, B. S.; Rensch, B.; Wäänänen, A.; Daskalakis, G.; Kyriakis, A.; Markou, C.; Simopoulou, E.; Siotis, I.; Vayaki, A.; Blondel, A.; Bonneaud, G.; Brient, J. C.; Bourdon, P.; Rougé, A.; Rumpf, M.; Valassi, A.; Verderi, M.; Videau, H.; Candlin, D. J.; Parsons, M. I.; Focardi, E.; Parrini, G.; Zachariadou, K.; Corden, M.; Georgiopoulos, C.; Jaffe, D. E.; Antonelli, A.; Bencivenni, G.; Bologna, G.; Bossi, F.; Campana, P.; Capon, G.; Casper, D.; Chiarella, V.; Felici, G.; Laurelli, P.; Mannocchi, G.; Murtas, F.; Murtas, G. P.; Passalacqua, L.; Pepe-Altarelli, M.; Curtis, L.; Dorris, S. J.; Halley, A. W.; Knowles, I. G.; Lynch, J. G.; O'Shea, V.; Raine, C.; Scarr, J. M.; Smith, K.; Teixeira-Dias, P.; Thompson, A. S.; Thomson, E.; Thomson, F.; Turnbull, R. M.; Geweniger, C.; Graefe, G.; Hanke, P.; Hansper, G.; Hepp, V.; Kluge, E. E.; Putzer, A.; Schmidt, M.; Sommer, J.; Tittel, K.; Werner, S.; Wunsch, M.; Beuselinck, R.; Binnie, D. M.; Cameron, W.; Dornan, P. J.; Girone, M.; Goodsir, S.; Martin, E. B.; Moutoussi, A.; Nash, J.; Sedgbeer, J. K.; Stacey, A. M.; Williams, M. D.; Dissertori, G.; Ghete, V. M.; Girtler, P.; Kuhn, D.; Rudolph, G.; Betteridge, A. P.; Bowdery, C. K.; Colrain, P.; Crawford, G.; Finch, A. J.; Foster, F.; Hughes, G.; Sloan, T.; Williams, M. I.; Galla, A.; Giehl, I.; Greene, A. M.; Hoffmann, C.; Jakobs, K.; Kleinknecht, K.; Quast, G.; Renk, B.; Rohne, E.; Sander, H.-G.; van Gemmeren, P.; Zeitnitz, C.; Aubert, J. J.; Benchouk, C.; Bonissent, A.; Bujosa, G.; Calvet, D.; Carr, J.; Coyle, P.; Diaconu, C.; Etienne, F.; Konstantinidis, N.; Leroy, O.; Motsch, F.; Payre, P.; Rousseau, D.; Talby, M.; Sadouki, A.; Thulasidas, M.; Trabelsi, K.; Aleppo, M.; Ragusa, F.; Berlich, R.; Blum, W.; Brown, D.; Büscher, V.; Dietl, H.; Dydak, F.; Ganis, G.; Gotzhein, C.; Kroha, H.; Lütjens, G.; Lutz, G.; Männer, W.; Moser, H.-G.; Richter, R.; Rosado-Schlosser, A.; Schael, S.; Settles, R.; Seywerd, H.; St. Denis, R.; Stenzel, H.; Wiedenmann, W.; Wolf, G.; Boucrot, J.; Callot, O.; Chen, S.; Choi, Y.; Cordier, A.; Davier, M.; Duflot, L.; Grivaz, J.-F.; Heusse, Ph.; Höcker, A.; Jacholkowska, A.; Jacquet, M.; Kim, D. W.; Le Diberder, F.; Lefrançois, J.; Lutz, A.-M.; Nilolic, I.; Schune, M.-H.; Simion, S.; Tournefier, E.; Veillet, J.-J.; Videau, I.; Zerwas, D.; Azzurri, P.; Bagliesi, G.; Batignani, G.; Bettarini, S.; Bozzi, C.; Calderini, G.; Carpinelli, M.; Ciocci, M. A.; Ciulli, V.; dell'Orso, R.; Fantechi, R.; Ferrante, I.; Foà, L.; Forti, F.; Giassi, A.; Giorgi, M. A.; Gregorio, A.; Ligabue, F.; Lusiani, A.; Marrocchesi, P. S.; Messineo, A.; Palla, F.; Sanguinetti, G.; Sciabà, A.; Spagnolo, P.; Steinberger, J.; Tenchini, R.; Tonelli, G.; Vannini, C.; Venturi, A.; Verdini, P. G.; Blair, G. A.; Bryant, L. M.; Chambers, J. T.; Gao, Y.; Green, M. G.; Medcalf, T.; Perrodo, P.; Strong, J. A.; von Wimmersperg-Toeller, J. H.; Botterill, D. R.; Clifft, R. W.; Edgecock, T. R.; Haywood, S.; Maley, P.; Norton, P. R.; Thompson, J. C.; Wright, A. E.; Bloch-Devaux, B.; Colas, P.; Emery, S.; Kozanecki, W.; Lançon, E.; Lemaire, M. C.; Locci, E.; Perez, P.; Rander, J.; Renardy, J.-F.; Roussarie, A.; Schuller, J.-P.; Schwindling, J.; Trabelsi, A.; Vallage, B.; Black, S. N.; Dann, J. H.; Johnson, R. P.; Kim, H. Y.; Litke, A. M.; McNeil, M. A.; Taylor, G.; Booth, C. N.; Boswell, R.; Brew, C. A. J.; Cartwright, S.; Combley, F.; Kelly, M. S.; Lehto, M.; Newton, W. M.; Reeve, J.; Thompson, L. F.; Böhrer, A.; Brandt, S.; Cowan, G.; Grupen, C.; Saraiva, P.; Smolik, L.; Stephan, F.; Apollonio, M.; Bosisio, L.; Della Marina, R.; Giannini, G.; Gobbo, B.; Musolino, G.; Rothberg, J.; Wasserbaech, S.; Armstrong, S. R.; Charles, E.; Elmer, P.; Ferguson, D. P. S.; Gao, Y. S.; González, S.; Greening, T. C.; Hayes, O. J.; Hu, H.; Jin, S.; McNamara, P. A.; Nachtman, J. M.; Nielsen, J.; Orejudos, W.; Pan, Y. B.; Saadi, Y.; Scott, I. J.; Walsh, J.; Sau, Lan Wu; Wu, X.; Yamartino, J. M.; Zobernig, G.

    1997-02-01

    A measurement of Rb using five mutually exclusive hemisphere tags has been performed by ALEPH using the full LEP1 statistics. Three tags are designed to select the decay of the Z0 to b quarks, while the remaining two selectZ0 decays to c and light quarks, and are used to measure the tagging efficiencies. The result, Rb = 0.2159 +/- 0.0009 (stat) +/- 0.0011 (syst), is in agreement with the electroweak theory prediction of 0.2158 +/- 0.0003.

  20. Interpretation of the CABRI-RAFT RB1 and RB2 tests through detailed data evaluation and PAPAS-2S code analysis

    International Nuclear Information System (INIS)

    Fukano, Yoshitaka; Sato, Ikken

    2001-08-01

    The CABRI-RAFT RB1 and RB2 tests were aiming at a study on impact of fuel pin failure under an overpower condition leading to fuel melting. Using a special technique, combination of through-cladding failure and fuel melting was realized. In the RB1 test, fuel ejection was prevented under a limited fuel melting condition. On the other hand, significant fuel melting was applied in the RB2 test so as to get the fuel ejection, thereby obtaining information on the fuel ejection behavior. Interpretation for these tests through the detailed experimental data evaluation and the PAPAS-2S code analysis is performed in this study. Through this study, it is indicated that molten fuel ejection can be prevented with the low smear density fuel as far as the fuel melting is not large for a slit-type cladding defect. Fuel ejection becomes possible in the case of significant fuel melting with a very thin solid fuel shell surrounding the molten fuel cavity. However, the rapidness of the fuel ejection with the low smear density fuel is less pronounced compared with that of the high smear density fuel. It is also confirmed that there is considerable DN-precursor release into the coolant flow already before fuel ejection. The result is very useful for evaluation of anomaly detection with DN signal observation. (author)

  1. Probing the structural and electronic properties of cationic rubidium-gold clusters: [AunRb]+ (n = 1-10)

    Science.gov (United States)

    Zhao, Ya-Ru; Zhang, Hai-Rong; Qian, Yu; Duan, Xu-Chao; Hu, Yan-Fei

    2016-03-01

    Density functional theory has been applied to study the geometric structures, relative stabilities, and electronic properties of cationic [AunRb]+ and Aun + 1+ (n = 1-10) clusters. For the lowest energy structures of [AunRb]+ clusters, the planar to three-dimensional transformation is found to occur at cluster size n = 4 and the Rb atoms prefer being located at the most highly coordinated position. The trends of the averaged atomic binding energies, fragmentation energies, second-order difference of energies, and energy gaps show pronounced even-odd alternations. It indicated that the clusters containing odd number of atoms maintain greater stability than the clusters in the vicinity. In particular, the [Au6Rb]+ clusters are the most stable isomer for [AunRb]+ clusters in the region of n = 1-10. The charges in [AunRb]+ clusters transfer from the Rb atoms to Aun host. Density of states revealed that the Au-5d, Au-5p, and Rb-4p orbitals hardly participated in bonding. In addition, it is found that the most favourable channel of the [AunRb]+ clusters is Rb+ cation ejection. The electronic localisation function (ELF) analysis of the [AunRb]+ clusters shown that strong interactions are not revealed in this study.

  2. Research Project 'RB research nuclear reactor' (operation and maintenance), Final report

    International Nuclear Information System (INIS)

    1985-01-01

    This final report covers operation and maintenance activities at the RB reactor during period from 1981-1985. First part covers the RB reactor operation, detailed description of reactor components, fuel, heavy water, reactor vessel, cooling system, equipment and instrumentation, auxiliary systems. It contains data concerned with dosimetry and radiation protection, reactor staff, and financial data. Second part deals maintenance, regular control and testing of reactor equipment and instrumentation. Third part is devoted to basic experimental options and utilization of the RB reactor including training

  3. Neutron converter at reactor RB; Konvertor neutrona na reaktoru RB

    Energy Technology Data Exchange (ETDEWEB)

    Strugar, P; Sotic, P; Ninkovic, M; Pesic, M [Boris Kidric Institute of nuclear sciences, Vinca, Belgrade (Yugoslavia)

    1977-07-01

    A neutron converter at Reactor RB in the 'Boris Kidric' Institute of Nuclear Sciences - Vinca has been constructed. Preliminary measurements have been shown that the converted neutron spectrum is very similar to the fission neutron spectrum. For the same integral reactor power, the measured neutron radiation dose has been for about ten times larger with the neutron converter. The neutron converter offers wide possibilities, as in investigations in the reactor physics, where the fission neutron spectra have been required, as well as in the field of neutron dosimetry and biological irradiations (author)

  4. Application of Sm/Eu/, Rb/Sr, Ce/Yb and F-Rb ratios to discriminate between Tin mineralized and non-mineralized S-type granites

    International Nuclear Information System (INIS)

    Karimpour, M.H.

    1998-01-01

    Mash had granites and Gran diorites are divided into three groups bas sed on their ages and composition: (1) Deh Now-Vakilabad-Kuhsangi Granodiorites and Quartz monzodiorites, (2) Sang bast Granite and (3) Khalaj- Gheshlagh Biotite-muscovite Granite. All these intrusive s belong to S-type granite, The oldest are in the range of intermediate and the youngest are acidic in composition. Intrusive rocks in the area of Deh now to Kuhsangi show trend of differentiation. Major, trace and rare earth elements within the source rocks of porphyry Sn, Mo, and Cu deposits were compared and very distinct differences were noticed. Differentiation index, Rb/Sr, Ce/Yb, and (Sr 87 /Sr 86 ) ratios can be used to identify the source rocks for porphyry Sn, Mo, or Cu. Major, as well as trace and rare earth elements of Mash had Granites and Granodiorites were compared with tin mineralized granites of the world. As a result, four diagrams were presented to be utilized in order to discriminate between Sn mineralized and non-mineralized granites. Such as Rb to the ratio of Sm/Eu, F to Rb and the three angle of F, Rb, Sr + Ba

  5. Multiple protein biomarker assessment for recombinant bovine somatotropin (rbST abuse in cattle.

    Directory of Open Access Journals (Sweden)

    Susann K J Ludwig

    Full Text Available Biomarker profiling, as a rapid screening approach for detection of hormone abuse, requires well selected candidate biomarkers and a thorough in vivo biomarker evaluation as previously done for detection of growth hormone doping in athletes. The bovine equivalent of growth hormone, called recombinant bovine somatotropin (rbST is (illegally administered to enhance milk production in dairy cows. In this study, first a generic sample pre-treatment and 4-plex flow cytometric immunoassay (FCIA were developed for simultaneous measurement of four candidate biomarkers selected from literature: insulin-like growth factor 1 (IGF-1, its binding protein 2 (IGFBP2, osteocalcin and endogenously produced antibodies against rbST. Next, bovine serum samples from two extensive controlled rbST animal treatment studies were used for in vivo validation and biomarker evaluation. Finally, advanced statistic tools were tested for the assessment of biomarker combination quality aiming to correctly identify rbST-treated animals. The statistical prediction tool k-nearest neighbours using a combination of the biomarkers osteocalcin and endogenously produced antibodies against rbST proved to be very reliable and correctly predicted 95% of the treated samples starting from the second rbST injection until the end of the treatment period and even thereafter. With the same biomarker combination, only 12% of untreated animals appeared false-positive. This reliability meets the requirements of Commission Decision 2002/657/EC for screening methods in veterinary control. From the results of this multidisciplinary study, it is concluded that the osteocalcin - anti-rbST-antibodies combination represent fit-for-purpose biomarkers for screening of rbST abuse in dairy cattle and can be reliably measured in both the developed 4-plex FCIA as well as in a cost-effective 2-plex microsphere-based binding assay. This screening method can be incorporated in routine veterinary monitoring

  6. First observation of isomeric state in {sup 97}Rb

    Energy Technology Data Exchange (ETDEWEB)

    Rudigier, Matthias; Blazhev, Andrey; Regis, Jean-Marc; Warr, Nigel; Jolie, Jan; Fransen, Christoph; Hackstein, Matthias; Pfeiffer, Michael; Rother, Wolfram; Thomas, Tim [IKP, Univ. Koeln (Germany); Simpson, Gary; Ramdhane, Mourad [LPSC, Grenoble (France); Koester, Ulli; Materna, Thomas; Urban, Waldemar [ILL, Grenoble (France); Daugas, Jean-Michel [CEA, DAM, DIF, Arpajon (France)

    2012-07-01

    Data on a new microsecond isomer in {sup 97}Rb are presented. The measurement was conducted at the LOHENGRIN mass separator at the ILL, Grenoble. We were able to deduce the level energy and lifetime of the state. The multipolarity of the transition to the ground state was determined using conversion electron spectroscopy. This information enabled us to assign a spin and parity to the state, based on quasi-particle-rotor model calculations. The nucleus {sup 97}Rb has neutron number 60, and is thus situated in the shape-phase transition line of the mass 100 nuclei. It is discussed how the new state fits into the region and the Rb-isotopic chain. Furthermore some new results on the decay of the 9/2{sup +} microsecond isomer of {sup 97}Sr are presented and discussed.

  7. Rb-intercalated C{sub 60} compounds studied by Inverse Photoemission Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Finazzi, M; Brambilla, A; Biagioni, P; Cattoni, A; Duo, L; Ciccacci, F; Braicovich, L [INFM and Dip di Fisica del Politecnico di Milano, Milano (Italy); Giovanelli, L; Goldoni, A [ELETTRA Basovizza (Italy)

    2004-07-01

    Full text: Since the discovery of superconductivity in alkali-doped solid C{sub 60}, the electronic structure of the host material (C{sub 60}) and the doped compounds (A{sub x}C{sub 60}, where A is an alkali metal), has been the subject of a considerable amount of work, both theoretical and experimental. The spectroscopic investigations of the alkali-doped C{sub 60} compounds has been mainly focussed on the valence states, while much less information is available on the unoccupied states. In particular, inverse photoemission data on the complete set of stable Rb{sub x}C{sub 60} compounds was, so far, still missing. We have performed Inverse Photoemission (IPE) spectroscopy on Rb{sub x}C{sub 60} compounds (x = 1, 3, 4, 6). IPE spectra were obtained using a band-pass photon detector (hv = 9.4 eV, FWHM = 0.7 eV) and scanning the kinetic energy of the electrons impinging on the sample. Rb was evaporated on C{sub 60} films (thickness = 6-12 atomic layers) grown in situ on a Cu(100) substrate. The temperature of the substrate was kept equal to T = 100 deg C, which is lower than the C{sub 60} sublimation temperature. The amount of Rb was checked by measuring the intensity of the C1s and Rb3d photoemission lines. After the required amount of Rb had been deposited, the samples were annealed to distillate the desired stable phase.

  8. Construction of Rb charge exchange cell and characteristic experiment for He- ion production

    International Nuclear Information System (INIS)

    Lee, Hee Seock; Bak, Jun Gyo; Bak, Hae Ill

    1991-01-01

    The Rb charge exchange cell is constructed as the He - ion source of the SNU 1.5-MV Tandem Van de Graaff accelerator. the characteristic experiments is carried out in order to determine the optimum operational conditions of the cell. The He + ion beam with the energy of 1 - 10 keV, extracted from the duoplasmatron ion source, is passed through the Rb vapor to become He - ions by the two step charge exchange reaction, i.e., He + + Rb → He o* + Rb + and He o* + Rb → He - + Rb + . From the experimental results, it is found that the maximum fractional yield of He - ions is produced at He + /ion energy of 7 keV. The optimum temperatures of the oven and the canal are determined to be 370 deg C and 95 deg C respectively. Under the optimum operational condition the maximum fractional yield of He - ions is 2.42 ± 0.02 5. This charge exchange cell is proved to be an effective system for the production of He - ions. (Author)

  9. A Measurement of $R_{b}$ using a Double Tagging Method

    CERN Document Server

    Abbiendi, G.; Alexander, G.; Allison, John; Altekamp, N.; Anderson, K.J.; Anderson, S.; Arcelli, S.; Asai, S.; Ashby, S.F.; Axen, D.; Azuelos, G.; Ball, A.H.; Barberio, E.; Barlow, Roger J.; Bartoldus, R.; Batley, J.R.; Baumann, S.; Bechtluft, J.; Behnke, T.; Bell, Kenneth Watson; Bella, G.; Bellerive, A.; Bentvelsen, S.; Bethke, S.; Betts, S.; Biebel, O.; Biguzzi, A.; Bird, S.D.; Blobel, V.; Bloodworth, I.J.; Bobinski, M.; Bock, P.; Bohme, J.; Bonacorsi, D.; Boutemeur, M.; Braibant, S.; Bright-Thomas, P.; Brigliadori, L.; Brown, Robert M.; Burckhart, H.J.; Burgard, C.; Burgin, R.; Capiluppi, P.; Carnegie, R.K.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, David G.; Chrisman, D.; Ciocca, C.; Clarke, P.E.L.; Clay, E.; Cohen, I.; Conboy, J.E.; Cooke, O.C.; Couyoumtzelis, C.; Coxe, R.L.; Cuffiani, M.; Dado, S.; Dallavalle, G.Marco; Davis, R.; De Jong, S.; del Pozo, L.A.; De Roeck, A.; Desch, K.; Dienes, B.; Dixit, M.S.; Dubbert, J.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Eatough, D.; Estabrooks, P.G.; Etzion, E.; Evans, H.G.; Fabbri, F.; Fanti, M.; Faust, A.A.; Fiedler, F.; Fierro, M.; Fleck, I.; Folman, R.; Furtjes, A.; Futyan, D.I.; Gagnon, P.; Gary, J.W.; Gascon, J.; Gascon-Shotkin, S.M.; Gaycken, G.; Geich-Gimbel, C.; Giacomelli, G.; Giacomelli, P.; Gibson, V.; Gibson, W.R.; Gingrich, D.M.; Glenzinski, D.; Goldberg, J.; Gorn, W.; Grandi, C.; Gross, E.; Grunhaus, J.; Gruwe, M.; Hanson, G.G.; Hansroul, M.; Hapke, M.; Harder, K.; Hargrove, C.K.; Hartmann, C.; Hauschild, M.; Hawkes, C.M.; Hawkings, R.; Hemingway, R.J.; Herndon, M.; Herten, G.; Heuer, R.D.; Hildreth, M.D.; Hill, J.C.; Hillier, S.J.; Hobson, P.R.; Hocker, James Andrew; Homer, R.J.; Honma, A.K.; Horvath, D.; Hossain, K.R.; Howard, R.; Huntemeyer, P.; Igo-Kemenes, P.; Imrie, D.C.; Ishii, K.; Jacob, F.R.; Jawahery, A.; Jeremie, H.; Jimack, M.; Jones, C.R.; Jovanovic, P.; Junk, T.R.; Karlen, D.; Kartvelishvili, V.; Kawagoe, K.; Kawamoto, T.; Kayal, P.I.; Keeler, R.K.; Kellogg, R.G.; Kennedy, B.W.; Klier, A.; Kluth, S.; Kobayashi, T.; Kobel, M.; Koetke, D.S.; Kokott, T.P.; Kolrep, M.; Komamiya, S.; Kowalewski, Robert V.; Kress, T.; Krieger, P.; von Krogh, J.; Kuhl, T.; Kyberd, P.; Lafferty, G.D.; Lanske, D.; Lauber, J.; Lautenschlager, S.R.; Lawson, I.; Layter, J.G.; Lazic, D.; Lee, A.M.; Lellouch, D.; Letts, J.; Levinson, L.; Liebisch, R.; List, B.; Littlewood, C.; Lloyd, A.W.; Lloyd, S.L.; Loebinger, F.K.; Long, G.D.; Losty, M.J.; Ludwig, J.; Lui, D.; Macchiolo, A.; Macpherson, A.; Mader, W.; Mannelli, M.; Marcellini, S.; Markopoulos, C.; Martin, A.J.; Martin, J.P.; Martinez, G.; Mashimo, T.; Mattig, Peter; McDonald, W.John; McKenna, J.; Mckigney, E.A.; McMahon, T.J.; McPherson, R.A.; Meijers, F.; Menke, S.; Merritt, F.S.; Mes, H.; Meyer, J.; Michelini, A.; Mihara, S.; Mikenberg, G.; Miller, D.J.; Mir, R.; Mohr, W.; Montanari, A.; Mori, T.; Nagai, K.; Nakamura, I.; Neal, H.A.; Nellen, B.; Nisius, R.; O'Neale, S.W.; Oakham, F.G.; Odorici, F.; Ogren, H.O.; Oreglia, M.J.; Orito, S.; Palinkas, J.; Pasztor, G.; Pater, J.R.; Patrick, G.N.; Patt, J.; Perez-Ochoa, R.; Petzold, S.; Pfeifenschneider, P.; Pilcher, J.E.; Pinfold, J.; Plane, David E.; Poffenberger, P.; Polok, J.; Przybycien, M.; Rembser, C.; Rick, H.; Robertson, S.; Robins, S.A.; Rodning, N.; Roney, J.M.; Roscoe, K.; Rossi, A.M.; Rozen, Y.; Runge, K.; Runolfsson, O.; Rust, D.R.; Sachs, K.; Saeki, T.; Sahr, O.; Sang, W.M.; Sarkisian, E.K.G.; Sbarra, C.; Schaile, A.D.; Schaile, O.; Scharf, F.; Scharff-Hansen, P.; Schieck, J.; Schmitt, B.; Schmitt, S.; Schoning, A.; Schroder, Matthias; Schumacher, M.; Schwick, C.; Scott, W.G.; Seuster, R.; Shears, T.G.; Shen, B.C.; Shepherd-Themistocleous, C.H.; Sherwood, P.; Siroli, G.P.; Sittler, A.; Skuja, A.; Smith, A.M.; Snow, G.A.; Sobie, R.; Soldner-Rembold, S.; Sproston, M.; Stahl, A.; Stephens, K.; Steuerer, J.; Stoll, K.; Strom, David M.; Strohmer, R.; Surrow, B.; Talbot, S.D.; Tanaka, S.; Taras, P.; Tarem, S.; Teuscher, R.; Thiergen, M.; Thomson, M.A.; von Torne, E.; Torrence, E.; Towers, S.; Trigger, I.; Trocsanyi, Z.; Tsur, E.; Turcot, A.S.; Turner-Watson, M.F.; Van Kooten, Rick J.; Vannerem, P.; Verzocchi, M.; Voss, H.; Wackerle, F.; Wagner, A.; Ward, C.P.; Ward, D.R.; Watkins, P.M.; Watson, A.T.; Watson, N.K.; Wells, P.S.; Wermes, N.; White, J.S.; Wilson, G.W.; Wilson, J.A.; Wyatt, T.R.; Yamashita, S.; Yekutieli, G.; Zacek, V.; Zer-Zion, D.

    1999-01-01

    The fraction of Z to bbbar events in hadronic Z decays has been measured by the OPAL experiment using the data collected at LEP between 1992 and 1995. The Z to bbbar decays were tagged using displaced secondary vertices, and high momentum electrons and muons. Systematic uncertainties were reduced by measuring the b-tagging efficiency using a double tagging technique. Efficiency correlations between opposite hemispheres of an event are small, and are well understood through comparisons between real and simulated data samples. A value of Rb = 0.2178 +- 0.0011 +- 0.0013 was obtained, where the first error is statistical and the second systematic. The uncertainty on Rc, the fraction of Z to ccbar events in hadronic Z decays, is not included in the errors. The dependence on Rc is Delta(Rb)/Rb = -0.056*Delta(Rc)/Rc where Delta(Rc) is the deviation of Rc from the value 0.172 predicted by the Standard Model. The result for Rb agrees with the value of 0.2155 +- 0.0003 predicted by the Standard Model.

  10. Operation and maintenance of the RB reactor, Annual report for 1977; Pogon i odrzavanje reaktora RB, Izvestaj o radu u 1977. godini

    Energy Technology Data Exchange (ETDEWEB)

    Sotic, O; Vranic, S [Boris Kidric Institute of Nuclear Sciences Vinca, Beograd (Yugoslavia)

    1977-07-01

    The annual report for 1977 includes the following: utilization of the RB reactor; new regulations and instructions for reactor operation; improvement of experimental possibilities of the RB reactor; state of the reactor equipment; dosimetry and radiation protection; reactor staff. Five annexes are concerned with: testing the properties of preamplifiers for linear and logarithmic experimental channels; properties of the neutron converter; maintenance of the reactor equipment; purchase of new equipment; and the program for training reactor operators.

  11. Studies of rubidium selenate with secondary phase of RbOH under humidified reducing atmosphere

    International Nuclear Information System (INIS)

    Beyribey, Berceste; Hallinder, Jonathan; Poulsen, Finn Willy; Bonanos, Nikolaos; Mogensen, Mogens

    2012-01-01

    Highlights: ► Degradation of Rb 2 SeO 3 and Rb 2 SeO 4 to form RbOH provide protonic conductivity. ► The conductivity increases by increasing temperature. ► The highest conductivity value of 2.01·10 −4 S cm −1 is observed at 317 °C. ► The work may state conductivity rise in solid acid electrolytes upon decomposition. - Abstract: The high temperature properties of Rb 2 SeO 4 have been studied by calorimetry, impedance spectroscopy and X-ray powder diffraction. As synthesized, Rb 2 SeO 4 includes a second phase of Rb 2 SeO 3 , which can be eliminated upon heating the compound. As expected, no conductivity is observed in dry (pH 2 O 2 O = 0.1 bar) air at 176 °C, the conductivity increases sharply from 8.6·10 −8 to 1.7·10 −6 S cm −1 . Under humidified (pH 2 O = 0.1 bar) reducing atmosphere (9%H 2 in N 2 ), the conductivity increases to 2.0·10 −4 S cm −1 at 317 °C. Degradation of Rb 2 SeO 3 and Rb 2 SeO 4 to form RbOH, which is known as a proton conductor, are thought to be responsible for the observed conductivity in humidified atmospheres. Our observations may explain the conductivity rise in other solid acid electrolytes, including sulfate and selenate groups, around their decomposition temperatures, in humidified atmospheres.

  12. RB Research nuclear reactor, Annual report for 2006

    International Nuclear Information System (INIS)

    Milosevic, M.; Ljubenov, V.; Pesic, M.; Jevremovic, M.; Minic, D.

    2007-01-01

    Report on RB reactor operation during 2006 contains 3 parts. Part one contains a brief description of the reactor, reactor operation and operational capabilities, reactor components, relevant dosimetry and radiation protection issues, personnel and financial data. Part two is devoted to maintenance of the reactor components, namely, fuel, heavy water, reactor vessel, heavy water circulation system, absorption rods and heavy water level meters, maintenance of electronic, mechanical, electrical and auxiliary equipment. Part three contains detailed data concerned with measurements performed at the RB reactor and a number of significant results obtained

  13. R$_{b}$ - R$_{c}$ crisis and new physics

    CERN Document Server

    Bhattacharya, G; Hou Wei Shu; Bhattacharyya, Gautam; Branco, Gustavo C; Hou, Wei Shu

    1996-01-01

    The experimental values of R_b and R_c are the only data which do not seem to agree with Standard Model predictions. Although it is still premature to draw any definite conclusions, it is timely to look for new physics which could explain the excess in R_b and deficit in R_c. We investigate this problem in a simple extension of the Standard Model, where a charge +2/3 isosinglet quark is added to the standard spectrum. Upon the further introduction of an extra scalar doublet, one finds a solution with interesting consequences.

  14. SUNF, Simplified UNF Code, Fast Neutron Calculation by Unified Hauser-Feshbach Theory

    International Nuclear Information System (INIS)

    Zhang Jingshang

    2001-01-01

    1 - Description of program or function: The SUNF code is the simplified version of UNF code and is based on the unified Hauser-Feshbach and exciton model. SUNF code has been developed for calculations of fast neutron data for structural materials with neutron energies below 20 MeV. Besides elastic scattering channel, the code may handle decay sequence up to (n,3n) reaction, including 14 reaction channels. The energy spectra can be obtained and the output form is in the ENDF/B-6 format, but in file 5 form. For the ENDF-B-6 output, the incident energies are divided into two types: only cross section calculation; and those including neutron energy spectra. 2 - Methods: Gaussian integration is used for all numerical integration. 3 - Restrictions on the complexity of the problem: The incident energies of neutrons are from 1 KeV to 20 MeV. There are two parameters in this code: incident neutron energies number 'NEL'; and the number of discrete levels of residual nuclei for the first particle emissions 'NLV'. The users can set the values of NEL and NLV according to the storage size of the computer used. The number of discrete levels of residual nuclei for the multi-particle emissions is not greater than 20

  15. Electronic parameters and top surface chemical stability of RbPb{sub 2}Br{sub 5}

    Energy Technology Data Exchange (ETDEWEB)

    Atuchin, V.V., E-mail: atuchin@thermo.isp.nsc.ru [Laboratory of Optical Materials and Structures, Institute of Semiconductor Physics, SB RAS, Novosibirsk 90, 630090 (Russian Federation); Isaenko, L.I. [Laboratory of Crystal Growth, Institute of Geology and Mineralogy, SB RAS, Novosibirsk 90, 630090 (Russian Federation); Kesler, V.G. [Laboratory of Physical Principles for Integrated Microelectronics, Institute of Semiconductor Physics, SB RAS, Novosibirsk 90, 630090 (Russian Federation); Pokrovsky, L.D. [Laboratory of Optical Materials and Structures, Institute of Semiconductor Physics, SB RAS, Novosibirsk 90, 630090 (Russian Federation); Tarasova, A.Yu. [Laboratory of Crystal Growth, Institute of Geology and Mineralogy, SB RAS, Novosibirsk 90, 630090 (Russian Federation)

    2012-01-16

    Highlights: Black-Right-Pointing-Pointer Bridgman growth of RbPb{sub 2}Br{sub 5} crystal. Black-Right-Pointing-Pointer Electronic structure measurements with XPS. Black-Right-Pointing-Pointer Optical crystalline surface fabrication. - Abstract: The RbPb{sub 2}Br{sub 5} crystal has been grown by Bridgman method. The electronic structure of RbPb{sub 2}Br{sub 5} has been measured with XPS for a powder sample. High chemical stability of RbPb{sub 2}Br{sub 5} surface is verified by weak intensity of O 1s core level recorded by XPS and structural RHEED measurements. Chemical bonding effects have been observed by the comparative analysis of element core levels and crystal structure of RbPb{sub 2}Br{sub 5} and several rubidium- and lead-containing bromides using binding energy difference parameters {Delta}{sub Rb} = (BE Rb 3d - BE Br 3d) and {Delta}{sub Pb} = (BE Pb 4f{sub 7/2} - BE Br 3d).

  16. Weisskopf–Ewing and Hauser–Feshbach calculations of photonuclear cross sections used for electromagnetic dissociation

    International Nuclear Information System (INIS)

    Adamczyk, Anne M.; Norbury, John W.; Townsend, Lawrence W.

    2013-01-01

    The Weisskopf–Ewing (WE) and Hauser–Feshbach (HF) theory are statistical methods, which are often used to calculate photonuclear cross sections for compound nucleus reactions. In our past work, WE methodology was presented and photonuclear reaction cross sections for nucleon emission were calculated using WE theory. Here, our previous results, which neglect pre-equilibrium emissions and do not include multiple particle emission, are compared to those calculated with HF theory and experimental data. For the reactions considered herein, it is found that the WE theory and HF method are in reasonable agreement below the two neutron separation energy assuming an energy dependent branching ratio for intermediate and heavy nuclei. In addition, qualitative confidence of WE theory for electromagnetic dissociation (EMD) cross section calculations was found. - Author-Highlights: • The Weisskopf–Ewing (WE) theory is reviewed. • Photonuclear cross sections calculated with WE theory are compared to HF predictions. • The WE theory and the HF method give similar photonuclear cross sections. • Qualitative confidence of WE theory for EMD cross section calculations is found

  17. Fundamental and high-order anapoles in all-dielectric metamaterials via Fano–Feshbach modes competition

    KAUST Repository

    Gongora, J. S. Totero

    2017-02-01

    One of the most fascinating possibilities enabled by metamaterials is the strong reduction of the electromagnetic scattering from nanostructures. In dielectric nanoparticles, the formation of a minimal scattering state at specific wavelengths is associated with the excitation of photonic anapoles, which represent a peculiar type of radiationless state and whose existence has been demonstrated experimentally. In this work, we investigate the formation of anapole states in generic dielectric structures by applying a Fano-Feshbach projection scheme, a general technique widely used in the study of quantum mechanical open systems. By expressing the total scattering from the structure in terms of an orthogonal set of internal and external modes, defined in the interior and in the exterior of the dielectric structure, respectively, we show how anapole states are the result of a complex interaction among the resonances of the system and the surrounding environment. We apply our approach to a circular resonator, where we observe the formation of higher-order anapole states, which are originated by the superposition of several internal resonances of the system.

  18. A simplified unified Hauser-Feshbach/Pre-Equilibrium model for calculating double differential cross sections

    International Nuclear Information System (INIS)

    Fu, C.Y.

    1988-01-01

    A unified Hauser-Feshbach/Pre-Equilibrium model is extended and simplified. The extension involves the addition of correlations among states of different total quantum numbers (J and J') and the introduction of consistent level density formulas for the H-F and the P-E parts of the calculation. The simplification, aimed at reducing the computational cost, is achieved mainly by keeping only the off-diagonal terms that involve strongly correlated 2p-1h states. A correlation coefficient is introduced to fit the experimental data. The model has been incorporated into the multistep H-F model code TNG. Calculated double differential (n,xn) cross sections at 14 and 25.7 MeV for iron, niobium, and bismuth are in good agreement with experiments. In use at ORNL and JAERI, the TNG code in various stages of development has been applied with success to the evaluation of double differential (n,xn) cross sections from 1 to 20 MeV for the dominant isotopes of chromium, manganese, iron, nickel, copper, and lead. 11 refs., 2 figs

  19. RB1CC1 Protein Suppresses Type II Collagen Synthesis in Chondrocytes and Causes Dwarfism*

    Science.gov (United States)

    Nishimura, Ichiro; Chano, Tokuhiro; Kita, Hiroko; Matsusue, Yoshitaka; Okabe, Hidetoshi

    2011-01-01

    RB1-inducible coiled-coil 1 (RB1CC1) functions in various processes, such as cell growth, differentiation, senescence, apoptosis, and autophagy. The conditional transgenic mice with cartilage-specific RB1CC1 excess that were used in the present study were made for the first time by the Cre-loxP system. Cartilage-specific RB1CC1 excess caused dwarfism in mice without causing obvious abnormalities in endochondral ossification and subsequent skeletal development from embryo to adult. In vitro and in vivo analysis revealed that the dwarf phenotype in cartilaginous RB1CC1 excess was induced by reductions in the total amount of cartilage and the number of cartilaginous cells, following suppressions of type II collagen synthesis and Erk1/2 signals. In addition, we have demonstrated that two kinds of SNPs (T-547C and C-468T) in the human RB1CC1 promoter have significant influence on the self-transcriptional level. Accordingly, human genotypic variants of RB1CC1 that either stimulate or inhibit RB1CC1 transcription in vivo may cause body size variations. PMID:22049074

  20. Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma

    DEFF Research Database (Denmark)

    Møller, Michael Boe; Kania, P W; Ino, Y

    2000-01-01

    In the present study, we analysed 34 de novo diffuse large B cell lymphoma (DLCL) from a population-based lymphoma registry for alterations of the RB1 pathway at the genetic (RB1 and CDK4) and protein (pRb, cyclin D1, cyclin D3, CDK4, and E2F-1) level. The results were correlated with the data fr...

  1. The Re-evaluation of {sup 84}Rb decay data

    Energy Technology Data Exchange (ETDEWEB)

    Xiaolong, Huang; Chunmei, Zhou [Chinese Nuclear Data Center, Beijing, BJ (China)

    1996-06-01

    The {sup 84}Rb is an important radionuclide and its decay data are fundamental data in nuclear applications. The decay data for {sup 84}Rb were re-evaluated. The energies and intensities of {gamma} rays and their internal conversion coefficients, energies and intensities of Auger electrons, conversion electrons and x-rays, were recommended. The decay scheme was also given. The balance of radiation rays intensities and energies was checked. (9 tabs., 2 figs.).

  2. The origin of the RB1 imprint.

    Directory of Open Access Journals (Sweden)

    Deniz Kanber

    Full Text Available The human RB1 gene is imprinted due to a differentially methylated CpG island in intron 2. This CpG island is part of PPP1R26P1, a truncated retrocopy of PPP1R26, and serves as a promoter for an alternative RB1 transcript. We show here by in silico analyses that the parental PPP1R26 gene is present in the analysed members of Haplorrhini, which comprise Catarrhini (Old World Monkeys, Small apes, Great Apes and Human, Platyrrhini (New World Monkeys and tarsier, and Strepsirrhini (galago. Interestingly, we detected the retrocopy, PPP1R26P1, in all Anthropoidea (Catarrhini and Platyrrhini that we studied but not in tarsier or galago. Additional retrocopies are present in human and chimpanzee on chromosome 22, but their distinct composition indicates that they are the result of independent retrotransposition events. Chimpanzee and marmoset have further retrocopies on chromosome 8 and chromosome 4, respectively. To examine the origin of the RB1 imprint, we compared the methylation patterns of the parental PPP1R26 gene and its retrocopies in different primates (human, chimpanzee, orangutan, rhesus macaque, marmoset and galago. Methylation analysis by deep bisulfite sequencing showed that PPP1R26 is methylated whereas the retrocopy in RB1 intron 2 is differentially methylated in all primates studied. All other retrocopies are fully methylated, except for the additional retrocopy on marmoset chromosome 4, which is also differentially methylated. Using an informative SNP for the methylation analysis in marmoset, we could show that the differential methylation pattern of the retrocopy on chromosome 4 is allele-specific. We conclude that the epigenetic fate of a PPP1R26 retrocopy after integration depends on the DNA sequence and selective forces at the integration site.

  3. Special K: testing the potassium link between radioactive rubidium (86Rb) turnover and metabolic rate.

    Science.gov (United States)

    Tomlinson, Sean; Mathialagan, Priya D; Maloney, Shane K

    2014-04-01

    The measurement of (86)Rb turnover recently has been suggested as a useful method for measuring field metabolic rate in small animals. We investigated a proposed mechanism of (86)Rb turnover, its analogy to K(+), by comparing the turnover of (86)Rb in a model insect, the rhinoceros beetle Xylotrupes gideon, fed a diet of plum jam or plum jam enriched with K(+) or Rb(+). The turnover of (86)Rb in the beetles on the K(+) and the Rb(+) diets was higher than that for beetles on the jam diet (F2,311=32.4; P=1.58×10(-13)). We also exposed the beetles to different ambient temperatures to induce differences in metabolic rate ( ) while feeding them the jam and K(+) diets. was higher at higher ambient temperature (Ta) for both jam (F1,11=14.56; P=0.003) and K(+) (F1,8=15.39; P=0.004) dietary groups, and the turnover of (86)Rb was higher at higher Ta for both jam (F1,11=10.80; P=0.007) and K(+) (F1,8=12.34; P=0.008) dietary groups. There was a significant relationship between (86)Rb turnover and for both the jam (F1,11=35.00; P=1.0×10(-3)) and the K(+) (F1,8=64.33; P=4.3×10(-5)) diets, but the relationship differed between the diets (F1,19=14.07; P=0.001), with a higher (86)Rb turnover in beetles on the K(+)-enriched than on the jam diet at all Ta. We conclude that (86)Rb turnover is related to K(+) metabolism, and that this is the mechanism of the relationship between (86)Rb turnover and . Studies relating (86)Rb turnover to should maintain dietary [K] as close as possible to that of natural diets for the most accurate calibrations for free-ranging animals.

  4. Absorption spectra of thin films of triple compounds in the system RbIPbI2

    International Nuclear Information System (INIS)

    Yunakova, O.N.; Miloslavskij, V.K.; Ksenofontova, E.V.; Kovalenko, E.N.

    2012-01-01

    A formation of compounds RbPbI 3 and Rb 4 PbI 6 in the system RbI-PbI 2 is revealed and their absorption spectra are investigated in an energy interval 2-6 eV and a temperatures range 90-500 K. It is established that the low-frequency exciton excitations are localized in PbI 6 4- structural elements of the crystal lattice, they are classified as excitons of intermediate coupling and are of a three-dimensional character in RbPbI 3 and a quasi-two-dimensional one in Rb 4 PbI 6 .

  5. Environmental effects on energy metabolism and 86Rb elimination rates of fishes

    International Nuclear Information System (INIS)

    Peters, E.L.

    1994-01-01

    Relationships between energy metabolism and the turnover rates of number of important chemical and radiological elements (particularly the Group IA alkali metals: K, Rb, and Cs) have been observed in fishes. Using response surface statistics and fractional factorial ANOVA, the author examined the relative influences of temperature, salinity, food intake rate, mass, and their first order interactions on routine energy metabolism and 86 Rb elimination rates. Routine metabolic rates were increased primarily by increased temperature and salinity, with a strong body mass effect and a significant effect of food intake. 86 Rb elimination rates were increased primarily by increased temperature and salinity. There were no interactive effects between mass and either temperature or salinity for either routine energy metabolism or 86 Rb elimination rates. There was a significant interaction effect between temperature and salinity on routine energy metabolism rates, but not on 86 Rb elimination. The authors also observed a relationship between routine energy metabolism and 86 Rb elimination rates that may possibly be exploited as a means of estimating energy metabolic rates of fishes in the field. The statistical techniques used in this experiment have broad potential applications in assessing the contributions of combinations of environmental variables on contaminant kinetics, as well as in multiple toxicity testing, in that they greatly simplify experimental designs compared with traditional full-factorial methods

  6. Perfusion imaging using rubidium-82 ((82)Rb) PET in rats with myocardial infarction

    DEFF Research Database (Denmark)

    Clemmensen, Andreas Ettrup; Ghotbi, Adam Ali; Bodholdt, Rasmus Poul

    2017-01-01

    Assessing myocardial perfusion using 82Rb-PET is emerging as a valuable clinical tool.1,2 The rapid decay (T½ = 76 s) allows for absolute quantification of both rest and stress perfusion within 30 minutes. In addition to evaluation of epicardial disease with perfusion defects, also evaluation...... of balanced coronary and small vessel disease is possible. For further evaluation of how 82Rb-PET can be used clinically, pre-clinical application of the method would be valuable. However, so far no data on the use of 82Rb-PET in small animals have been published nor has the use of 82Rb-PET, to the best...

  7. Coupled fast-thermal system at the 'RB' nuclear reactor

    International Nuclear Information System (INIS)

    Pesic, M.

    1987-04-01

    The results of the analyses of the possibility of the coupled fast-thermal system (CFTS) design at the 'RB' nuclear reactor are shown. As the proof of the theoretical analyses the first stage CFTS-1 has been designed, realized, and tested. The excellent agreement between the results of the CFTS-1 studies and the theoretical predictions opens a straight way to the second, the final stage - realization of the designed CFST at the 'RB' nuclear reactor. (author)

  8. Study of reactor parameters of on critical systems, Phase I: Safety report for RB zero power reactor; Ispitivanje reaktorskih parametara na kriticnim sistemima, I faza: Izvestaj o sigurnosti reaktora nulte snage RB

    Energy Technology Data Exchange (ETDEWEB)

    Raisic, N [Boris Kidric Institute of Nuclear Sciences Vinca, Belgrade (Yugoslavia)

    1962-09-15

    In addition to the safety analysis for the zero power RB reactor, this report contains a general description of the reactor, reactor components, auxiliary equipment and the reactor building. Reactor Rb has been reconstructed during 1961-1962 and supplied with new safety-control system as well as with a complete dosimetry instrumentation. Since RB reactor was constructed without shielding special attention is devoted to safety and protection of the staff performing experiments. Due to changed circumstances in the Institute ( start-up of the RA 7 MW power reactor) the role of the RB reactor was redefined.

  9. Double photoionisation in Rb and Cs in the threshold region

    International Nuclear Information System (INIS)

    Holland, D.M.P.; Codling, K.

    1981-01-01

    The extreme ultraviolet radiation emitted by the Bonn 2.5-GeV electron synchrotron, monochromatised by a 1-m vertically-dispersing Seya. The radiation, of 2 Angstroem band-pass (0.15 eV at 30 eV), was incident on an atomic beam of Rb or Cs vapour produced by a resistively heated oven. To avoid excessive oxidation, the oven was loaded with the alkali metal still under petroleum spirit and the residual spirit removed on evacuation of the system. The drift tube of a time-of-flight (TOF) mass spectrometer was placed at right angles to both the photon and atomic beams. The singly and doubly charged ions were pulsed out of the interaction region and detected by a microchannel-plate assembly placed at the end of the drift tube. The results for Rb are neither so accurate nor extensive as for Cs because a peak at mass number 44 in the TOF spectrum (probably CO 2 ), due to emission from the oven region, obscured the small Rb 2+ peak. The results for both Rb and Cs are shown as the ratios of double-to-single photoionisation. (orig./AH)

  10. Uptake of /sup 86/Rb/sup +/ into photoautotrophic mesophyll cells of Papaver somniferum

    Energy Technology Data Exchange (ETDEWEB)

    Kaiser, W.M.; Jeschke, W.D.; Hartung, W.

    1982-06-01

    Uptake of /sup 86/Rb/sup +/, used as a tracer for potassium, into isolated photoautotrophic mesophyll cells of Papaver somniferum was weakly but consistently stimulated in the light. It showed mono-phasic saturation kinetics with a pH optimum of 7.0, a Vsub(max) of 6.7 ..mu..mol mg/sup -1/ Chl x h/sup -1/ and a Ksub(m) of 2.7 mmol l/sup -1/. Different anions as Cl/sup -/, NO/sub 3//sup -/ and PO/sub 4//sup 3 -/ had no effects on /sup 86/Rb/sup +/ uptake. Sodium ions influenced Rb/sup +/-uptake very weakly, indicating a high K/sup +/ -specificity of the mesophyll cell plasmalemma. Fusicoccin stimulated /sup 86/Rb/sup +/ -uptake strongly whereas abscisic acid inhibited uptake only following preincubation for two hours. Nitrite, CCCP and Dio-9 inhibited /sup 86/Rb/sup +/-uptake which gives evidence that this process is dependent on intact pH-gradients within the cells and on ATP-formation.

  11. Theoretical model for ultracold molecule formation via adaptive feedback control

    International Nuclear Information System (INIS)

    Poschinger, Ulrich; Salzmann, Wenzel; Wester, Roland; Weidemueller, Matthias; Koch, Christiane P; Kosloff, Ronnie

    2006-01-01

    We theoretically investigate pump-dump photoassociation of ultracold molecules with amplitude- and phase-modulated femtosecond laser pulses. For this purpose, a perturbative model for light-matter interaction is developed and combined with a genetic algorithm for adaptive feedback control of the laser pulse shapes. The model is applied to the formation of 85 Rb 2 molecules in a magneto-optical trap. We find that optimized pulse shapes may maximize the formation of ground state molecules in a specific vibrational state at a pump-dump delay time for which unshaped pulses lead to a minimum of the formation rate. Compared to the maximum formation rate obtained for unshaped pulses at the optimum pump-dump delay, the optimized pulses lead to a significant improvement of about 40% for the target level population. Since our model yields the spectral amplitudes and phases of the optimized pulses, the results are directly applicable in pulse shaping experiments

  12. Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase.

    Science.gov (United States)

    McBrayer, Samuel K; Olenchock, Benjamin A; DiNatale, Gabriel J; Shi, Diana D; Khanal, Januka; Jennings, Rebecca B; Novak, Jesse S; Oser, Matthew G; Robbins, Alissa K; Modiste, Rebecca; Bonal, Dennis; Moslehi, Javid; Bronson, Roderick T; Neuberg, Donna; Nguyen, Quang-De; Signoretti, Sabina; Losman, Julie-Aurore; Kaelin, William G

    2018-04-17

    Inactivation of the retinoblastoma gene ( RB1 ) product, pRB, is common in many human cancers. Targeting downstream effectors of pRB that are central to tumorigenesis is a promising strategy to block the growth of tumors harboring loss-of-function RB1 mutations. One such effector is retinoblastoma-binding protein 2 (RBP2, also called JARID1A or KDM5A), which encodes an H3K4 demethylase. Binding of pRB to RBP2 has been linked to the ability of pRB to promote senescence and differentiation. Importantly, genetic ablation of RBP2 is sufficient to phenocopy pRB's ability to induce these cellular changes in cell culture experiments. Moreover, germline Rbp2 deletion significantly impedes tumorigenesis in Rb1 +/- mice. The value of RBP2 as a therapeutic target in cancer, however, hinges on whether loss of RBP2 could block the growth of established tumors as opposed to simply delaying their onset. Here we show that conditional, systemic ablation of RBP2 in tumor-bearing Rb1 +/- mice is sufficient to slow tumor growth and significantly extend survival without causing obvious toxicity to the host. These findings show that established Rb1 -null tumors require RBP2 for growth and further credential RBP2 as a therapeutic target in human cancers driven by RB1 inactivation.

  13. Zero energy reactor 'RB'

    Energy Technology Data Exchange (ETDEWEB)

    Popovic, D; Takac, S; Markovic, H; Raisic, N; Zdravkovic, Z; Radanovic, Lj [Boris Kidric Institute of Nuclear Sciences, Vinca, Beograd (Yugoslavia)

    1959-03-15

    In 1958 the zero energy reactor RB was built with the purpose of enabling critical experiments with various reactor systems to be carried out. The first core assembly built in this reactor consists of heavy water as moderator and natural uranium metal as fuel. In order to be able to obtain very accurate results when measuring the main characteristics of the assembly the reactor was built as a completely bare system. (author)

  14. Rb/Sr establishes an age of 61 to 67 Ma for Colombian emeralds

    International Nuclear Information System (INIS)

    Ordonez, F Romero; Kawashita, Koji; Schultz-Guttler, R

    2001-01-01

    The age of emeralds is related to the environment within which they form and can be dated by geochronological methods of which the rubidium-strontium (Rb-Sr) method (Faure, 1986) is the best to date the emeralds and its host rocks (Vidal et al., 1992). Isotopic studies done by Vidal et al. (1992) established two different geochronological environments for dating emeralds depending on their ages: emeralds from Precambrian rocks in Brazil, Madagascar and Zambia with high radiogenic strontium enrichment due to the older ages and high Rb contents and emeralds hosted by younger rocks in Colombia, Paquistan and Afganistan generally, with low 87 Rb/ 86 Sr range and low radiogenic Sr enrichment, and low content of Rb (au)

  15. Rb-Sr isochrone dating of granitoids from Tribec Mts

    International Nuclear Information System (INIS)

    Bagdasaryan, G.P.; Gukasyan, R.Kh.; Cambel, B.; Broska, I.

    1990-01-01

    The results of Rb-Sr isochrone dating of granitoids from the Tribec-Zobor crystalline complex region are presented. Whole-rock Rb-Sr isochrone indicates an age of 352±5 m.y., the initial ratio being ( 87 Sr/ 86 Sr) 0 =0.70582±0.00008, which approaches the hitherto published initial ratios from the Tatric-Veporide part of the crystalline complex. This indicates a common source of granitoid rocks over the entire region studied. (author). 2 figs., 1 tab., 15 refs

  16. Microbial transformation of ginsenoside Rb1 to compound K by Lactobacillus paralimentarius.

    Science.gov (United States)

    Quan, Lin-Hu; Kim, Yeon-Ju; Li, Guan Hao; Choi, Kwang-Tea; Yang, Deok-Chun

    2013-06-01

    In this study, the major ginsenoside Rb1 was transformed into the more pharmacologically active minor compound K by food grade Lactobacillus paralimentarius LH4, which was isolated from kimchi, a traditional Korean fermented food. The enzymatic reaction was analyzed by TLC, HPLC, and NMR. Using the cell-free enzyme of Lactobacillus paralimentarius LH4 at optimal conditions for 30 °C at pH 6.0, 1.0 mg ml(-1) ginsenoside Rb1 was transformed into 0.52 mg ml(-1) compound K within 72 h, with a corresponding molar conversion yield of 88 %. The cell-free enzyme hydrolyzed the two glucose moieties attached to the C-3 position and the outer glucose moiety attached to the C-20 position of the ginsenoside Rb1. The cell-free enzyme hydrolyzed the ginsenoside Rb1 along the following pathway: ginsenoside Rb1 → gypenoside XVII and ginsenoside Rd → ginsenoside F2 → compound K. Our results indicate that Lactobacillus paralimentarius LH4 has the potential to be applied for the preparation of compound K in the food industry.

  17. Ginsenoside Rb1 for Myocardial Ischemia/Reperfusion Injury: Preclinical Evidence and Possible Mechanisms

    Directory of Open Access Journals (Sweden)

    Qun Zheng

    2017-01-01

    Full Text Available Ginseng is an important herbal drug that has been used worldwide for many years. Ginsenoside Rb1 (G-Rb1, the major pharmacological extract from ginseng, possesses a variety of biological activities in the cardiovascular systems. Here, we conducted a preclinical systematic review to investigate the efficacy of G-Rb1 for animal models of myocardial ischemia/reperfusion injury and its possible mechanisms. Ten studies involving 211 animals were identified by searching 6 databases from inception to May 2017. The methodological quality was assessed by using the CAMARADES 10-item checklist. All the data were analyzed using RevMan 5.3 software. As a result, the score of study quality ranged from 3 to 7 points. Meta-analyses showed that G-Rb1 can significantly decrease the myocardial infarct size and cardiac enzymes (including lactate dehydrogenase, creatine kinase, and creatine kinase-MB when compared with control group (P<0.01. Significant decrease in cardiac troponin T and improvement in the degree of ST-segment depression were reported in one study (P<0.05. Additionally, the possible mechanisms of G-Rb1 for myocardial infarction are antioxidant, anti-inflammatory, antiapoptosis, promoting angiogenesis and improving the circulation. Thus, G-Rb1 is a potential cardioprotective candidate for further clinical trials of myocardial infarction.

  18. RB Research nuclear reactor, Annual report for 1995, I-IV; Istrazivacki nuklearni reaktor RB, Izvestaj o radu u 1995. godini, I-IV

    Energy Technology Data Exchange (ETDEWEB)

    Stefanovic, D; Milosevic, M; Pesic, M [Institute of Nuclear Sciences Vinca, Belgrade (Yugoslavia); Marinkovic, P [Elektrotehnicki fakultet, Beograd (Yugoslavia); Ilic, R; Dasic, N; Milovanovic, S; Ljubenov, V; Petronijevic, M; Jevremovic, M [Institute of Nuclear Sciences Vinca, Belgrade (Yugoslavia)

    1995-12-15

    Report on RB reactor operation during 1995 contains 3 parts. Part one contains a brief description of reactor operation and reactor components, relevant dosimetry data and radiation protection issues, personnel and financial data. Part two is devoted to maintenance of the reactor components, namely, fuel, heavy water, reactor vessel, heavy water circulation system, absorption rods and heavy water level-meters, maintenance of electronic, mechanical, electrical and auxiliary equipment. Part three contains data concerned with reactor operation and utilization with a comprehensive list of publications resulting from experiments done at the RB reactor.

  19. Rb-Sr dating in orthogneisses and the age of Serido group, Brazil

    International Nuclear Information System (INIS)

    Macedo, M.H.F.; Sa, E.F.J. de; Sa, J.M.

    1984-01-01

    The conclusions of the geochronologic study, by Rb-Sr method, of orthogneisses from Serido Group, Northeast of Brazil, are presented. Metamorphic and granitic rocks were analysed by X-ray fluorescence, to determine the Rb and Sr quantity. (M.C.K.) [pt

  20. Studies of rubidium selenate with secondary phase of RbOH under humidified reducing atmosphere

    DEFF Research Database (Denmark)

    Beyribey, Berceste; Hallinder, Jonathan; Poulsen, Finn Willy

    2012-01-01

    The high temperature properties of Rb2SeO4 have been studied by calorimetry, impedance spectroscopy and X-ray powder diffraction. As synthesized, Rb2SeO4 includes a second phase of Rb2SeO3, which can be eliminated upon heating the compound. As expected, no conductivity is observed in dry (pH2O ....001 bar) air. By changing to humidified (pH2O = 0.1 bar) air at 176 deg. C, the conductivity increases sharply from 8.6·10-8 to 1.7·10-6 S cm-1. Under humidified (pH2O = 0.1 bar) reducing atmosphere (9%H2 in N2), the conductivity increases to 2.0·10-4 S cm-1 at 317 C. Degradation of Rb2SeO3 and Rb2SeO4...

  1. NaPdPS{sub 4} and RbPdPS{sub 4}: systems with infinite straight ((1)/({infinity}))[PdPS{sub 4}]{sup -} chains soluble in polar solvents and the structure of cubic RbPdPS{sub 4}{l_brace}Rb{sub 0.33}P{sub 0.4}S{sub 2.23}O{sub x}{r_brace}

    Energy Technology Data Exchange (ETDEWEB)

    Coste, Servane; Hanko, Jason; Bujoli-Doeuff, Martine; Louarn, Guy; Evain, Michel; Brec, Raymond; Alonso, Bruno; Jobic, S; Kanatzidis, Mercouri G

    2003-11-01

    The synthesis, crystal structures, chemical and spectroscopic properties of NaPdPS{sub 4}, RbPdPS{sub 4}, and RbPdPS{sub 4}{l_brace}Rb{sub 0.33}P{sub 0.4}S{sub 2.23}O{sub x}{r_brace} are described. NaPdPS{sub 4}, RbPdPS{sub 4}, are isostructural and crystallize in the tetragonal system I4/mcm with cell parameters a=7.3074(8) A, c=12.2308(14) A and a=8.2954(3) A, c=12.2284(4) A respectively. RbPdPS{sub 4}{l_brace}Rb{sub 0.33}P{sub 0.4}S{sub 2.23}O{sub x}{r_brace} is cubic, space group Pm-3n and a=12.0042(2) A. All compounds contain the same ((1)/({infinity}))[PdPS{sub 4}]{sup -} chains made of alternating square planar Pd{sup 2+} cations and tetrahedral [PS{sub 4}]{sup 3-} anions. RbPdPS{sub 4}{l_brace}Rb{sub 0.33}P{sub 0.4}S{sub 2.23}O{sub x}{r_brace} contains co-crystallized highly disordered molecular species encapsulated within [Rb{sub 8}] cubic cavities. Spectroscopic solid state {sup 31}P NMR, infrared and Raman data as well as elemental analysis suggest that these species could be S{sub n}{sup 2-} (n=3 or 4) anions and possibly cationic [P{sub 4}S{sub 6}O]{sup 6+} fragments. NaPdPS{sub 4} and RbPdPS{sub 4} exhibit exfoliative dissolution in polar solvents giving rise to solutions that show signs of complex fluid behavior.

  2. Production of 81Rb/sup 81m/Kr generators with 60-MeV protons at BLIP

    International Nuclear Information System (INIS)

    Mausner, L.F.; Richards, P.

    1983-01-01

    By bombarding natural krypton gas with approx. 63 MeV protons, 81 Rb is formed by (p,4n) reaction from high abundance 84 Kr (57%) as well as some additional contribution from 83 Kr (11.5%) and 82 Kr (11.6%) by (p,3n) and (p,2n) reactions, respectively. The production rate of 81 Rb is typically 1.5 mCi/μAh. This production rate is sufficient to create up to several hundred millicuries per run if necessary, enough for several high activity 81 Rb/sup 81m/Kr generators. Presently generators that deliver 10 to 20 mCi to the lungs are produced weekly for on-site use. The only other important activity in the solution is Rb-82m (6.4 hr). Small amounts of Br-76 (16.1 hr), Br-77 (57 hr), Br-82 (35.5 hr), Rb-83 (86.2 d), and Rb-84 (33 d) were also present. The bromine impurities pose no problem since they are not trapped on the generator. Rb-82m and Rb-84 decay to stable Kr-82 and Kr-84 in the generator and do not interfere with Kr-81m studies

  3. Topologically identical, but geometrically isomeric layers in hydrous α-, β-Rb[UO2(AsO3OH)(AsO2(OH)2)]·H2O and anhydrous Rb[UO2(AsO3OH)(AsO2(OH)2)

    Science.gov (United States)

    Yu, Na; Klepov, Vladislav V.; Villa, Eric M.; Bosbach, Dirk; Suleimanov, Evgeny V.; Depmeier, Wulf; Albrecht-Schmitt, Thomas E.; Alekseev, Evgeny V.

    2014-07-01

    The hydrothermal reaction of uranyl nitrate with rubidium nitrate and arsenic (III) oxide results in the formation of polymorphic α- and β-Rb[UO2(AsO3OH)(AsO2(OH)2)]·H2O (α-, β-RbUAs) and the anhydrous phase Rb[UO2(AsO3OH)(AsO2(OH)2)] (RbUAs). These phases were structurally, chemically and spectroscopically characterized. The structures of all three compounds are based upon topologically identical, but geometrically isomeric layers. The layers are linked with each other by means of the Rb cations and hydrogen bonding. Dehydration experiments demonstrate that water deintercalation from hydrous α- and β-RbUAs yields anhydrous RbUAs via topotactic reactions.

  4. Derivation of Apollo 14 High-Al Basalts at Discrete Times: Rb-Sr Isotopic Constraints

    Science.gov (United States)

    Hui. Hejiu; Neal, Clive, R.; Shih, Chi-Yu; Nyquist, Laurence E.

    2012-01-01

    Pristine Apollo 14 (A-14) high-Al basalts represent the oldest volcanic deposits returned from the Moon [1,2] and are relatively enriched in Al2O3 (>11 wt%) compared to other mare basalts (7-11 wt%). Literature Rb-Sr isotopic data suggest there are at least three different eruption episodes for the A-14 high-Al basalts spanning the age range approx.4.3 Ga to approx.3.95 Ga [1,3]. Therefore, the high-Al basalts may record lunar mantle evolution between the formation of lunar crust (approx.4.4 Ga) and the main basin-filling mare volcanism (groups [5,6], and then regrouped into three with a possible fourth comprising 14072 based on the whole-rock incompatible trace element (ITE) ratios and Rb-Sr radiometric ages [7]. However, Rb-Sr ages of these basalts from different laboratories may not be consistent with each other because of the use of different 87Rb decay constants [8] and different isochron derivation methods over the last four decades. This study involved a literature search for Rb-Sr isotopic data previously reported for the high-Al basalts. With the re-calculated Rb-Sr radiometric ages, eruption episodes of A-14 high-Al basalts were determined, and their petrogenesis was investigated in light of the "new" Rb-Sr isotopic data and published trace element abundances of these basalts.

  5. Dosimetry system of the RB reactor

    International Nuclear Information System (INIS)

    Lolic, B.; Vukadin, D.

    1962-01-01

    Although RB reactor is operated at very low power levels, safety and dosimetry systems have high importance. This paper shows detailed dosimetry system with fundamental typical components. Estimated radiation doses dependent on reactor power are given at some characteristic points in the rooms nearby reactor

  6. Ab Initio Study of Chemical Reactions of Cold SrF and CaF Molecules with Alkali-Metal and Alkaline-Earth-Metal Atoms: The Implications for Sympathetic Cooling.

    Science.gov (United States)

    Kosicki, Maciej Bartosz; Kędziera, Dariusz; Żuchowski, Piotr Szymon

    2017-06-01

    We investigate the energetics of the atom exchange reaction in the SrF + alkali-metal atom and CaF + alkali-metal atom systems. Such reactions are possible only for collisions of SrF and CaF with the lithium atoms, while they are energetically forbidden for other alkali-metal atoms. Specifically, we focus on SrF interacting with Li, Rb, and Sr atoms and use ab initio methods to demonstrate that the SrF + Li and SrF + Sr reactions are barrierless. We present potential energy surfaces for the interaction of the SrF molecule with the Li, Rb, and Sr atoms in their energetically lowest-lying electronic spin states. The obtained potential energy surfaces are deep and exhibit profound interaction anisotropies. We predict that the collisions of SrF molecules in the rotational or Zeeman excited states most likely have a strong inelastic character. We discuss the prospects for the sympathetic cooling of SrF and CaF molecules using ultracold alkali-metal atoms.

  7. Brain Transport Profiles of Ginsenoside Rb1 by Glucose Transporter 1: In Vitro and in Vivo

    Directory of Open Access Journals (Sweden)

    Yu-Zhu Wang

    2018-04-01

    Full Text Available Ginsenoside Rb1 (Rb1 has been demonstrated its protection for central nervous system and is apparently highly distributed to the brain. The objective of this study was to characterize Rb1 transport at the blood–brain barrier (BBB using primary cultured rat brain microvascular endothelial cells (rBMEC, an in vitro BBB model. The initial uptake velocity of Rb1 in rBMEC was temperature- and concentration-dependent, and was significantly reduced by phloretin, an inhibitor of GLUT1 transporter, but was independent of metabolic inhibitor. Furthermore, the transport of Rb1 into rBMEC was significantly diminished in the presence of natural substrate α-D-glucose, suggesting a facilitated transport of Rb1 via GLUT1 transporter. The impact of GLUT1 on the distribution of Rb1 between brain and plasma was studied experimentally in rats. Administration of phloretin (5 mg/kg, i.v. to normal rats for consecutive 1 week before Rb1 (10 mg/kg, i.v. at 0.5, 2, and 6 h did not alter Rb1 concentrations in plasma, but resulted in significant decreased brain concentrations of Rb1 compared to in the phloretin-untreated normal rats (489.6 ± 58.3 versus 105.1 ± 15.1 ng/g, 193.8 ± 11.1 versus 84.8 ± 4.1 ng/g, and 114.2 ± 24.0 versus 39.9 ± 4.9 ng/g, respectively. The expression of GLUT1 in the phloretin-treated group by western blotting analysis in vitro and in vivo experiments was significantly decreased, indicating that the decreased transport of Rb1 in brain was well related to the down-regulated function and level of GLUT1. Therefore, our in vitro and in vivo results indicate that the transport of Rb1 at the BBB is at least partly mediated by GLUT1 transporter.

  8. Complete neutronic nuclear data evaluation for 85Rb and 87Rb from 10-5 eV to 20 MeV

    International Nuclear Information System (INIS)

    Simon, Gerard; Prince, Augustus; Lalie, Evelyne.

    1981-04-01

    The total, elastic, inelastic, capture, (n,p), (n,d), (n,t), (n, 3 He), (n,α), (n,2n), (n,n'p), (n,n'α) cross-sections have been evaluated for 85 Rb and 87 Rb in the 10 -5 eV - 20 MeV energy range. This evaluation is based on available experimental data and theoretical calculations carried out in the framework of spherical optical model and statistical model. Angular distributions for elastic and discret inelastic scattering, and energy distributions for continuum inelastic scattering and for (n,2n) reaction have also been calculated. This evaluation, set under ENDF/BIV format, completes and plainly improves the corresponding evaluation given in the ENDF/BIV files [fr

  9. Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression.

    Directory of Open Access Journals (Sweden)

    Sathidpak Nantasanti

    Full Text Available The tumor suppressors Retinoblastoma (Rb and p53 are frequently inactivated in liver diseases, such as hepatocellular carcinomas (HCC or infections with Hepatitis B or C viruses. Here, we discovered a novel role for Rb and p53 in xenobiotic metabolism, which represent a key function of the liver for metabolizing therapeutic drugs or toxins. We demonstrate that Rb and p53 cooperate to metabolize the xenobiotic 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC. DDC is metabolized mainly by cytochrome P450 (Cyp3a enzymes resulting in inhibition of heme synthesis and accumulation of protoporphyrin, an intermediate of heme pathway. Protoporphyrin accumulation causes bile injury and ductular reaction. We show that loss of Rb and p53 resulted in reduced Cyp3a expression decreased accumulation of protoporphyrin and consequently less ductular reaction in livers of mice fed with DDC for 3 weeks. These findings provide strong evidence that synergistic functions of Rb and p53 are essential for metabolism of DDC. Because Rb and p53 functions are frequently disabled in liver diseases, our results suggest that liver patients might have altered ability to remove toxins or properly metabolize therapeutic drugs. Strikingly the reduced biliary injury towards the oxidative stress inducer DCC was accompanied by enhanced hepatocellular injury and formation of HCCs in Rb and p53 deficient livers. The increase in hepatocellular injury might be related to reduce protoporphyrin accumulation, because protoporphrin is well known for its anti-oxidative activity. Furthermore our results indicate that Rb and p53 not only function as tumor suppressors in response to carcinogenic injury, but also in response to non-carcinogenic injury such as DDC.

  10. Phase precipitation of Yb 2+ ions in RbCl monocrystals monitored ...

    African Journals Online (AJOL)

    Optical absorption spectra of RbCl:Yb2+ crystals have been measured at several elevated temperatures up to 300C. Results showed that in hot RbCl:Yb2+ crystals, the Yb2+ ions occupied lattice sites with effective octahedral, O, point symmetry. Values of an energy parameter , which is an approximate measure of the ...

  11. Operation of the Ca-dependent K(Rb)-transport in human lymphocytes

    Energy Technology Data Exchange (ETDEWEB)

    Szasz, I.; Sarkadi, B.; Gardos, G. (Orszagos Haematologiai es Vertranszfuzios Intezet, Budapest (Hungary))

    1982-01-01

    The transport pathways of the plasma membrane of human lymphocytes were studied based on /sup 86/Rb and /sup 45/Ca fluxes. Net Ca-uptake increases K(Rb)-permeability (Gardos-effect) and the membrane potential increases due to the subsequent K-efflux, enabling further Ca-uptake. The possible role of the above effects during lymphocyte stimulation is discussed.

  12. Determination of the Rb atomic number density in dense rubidium vapors by absorption measurements of Rb2 triplet bands

    International Nuclear Information System (INIS)

    Horvatic, Vlasta; Veza, Damir; Niemax, Kay; Vadla, Cedomil

    2008-01-01

    A simple and accurate way of determining atom number densities in dense rubidium vapors is presented. The method relies on the experimental finding that the reduced absorption coefficients of the Rb triplet satellite bands between 740 nm and 750 nm and the triplet diffuse band between 600 nm and 610 nm are not temperature dependent in the range between 600 K and 800 K. Therefore, the absolute values of the reduced absorption coefficients of these molecular bands can provide accurate information about atomic number density of the vapor. The rubidium absorption spectrum was measured by spatially resolved white-light absorption in overheated rubidium vapor generated in a heat pipe oven. The absolute values for the reduced absorption coefficients of the triplet bands were determined at lower vapor densities, by using an accurate expression for the reduced absorption coefficient in the quasistatic wing of the Rb D1 line, and measured triplet satellite bands to the resonance wing optical depth ratio. These triplet satellite band data were used to calibrate in absolute scale the reduced absorption coefficients of the triplet diffuse band at higher temperatures. The obtained values for the reduced absorption coefficient of these Rb molecular features can be used for accurate determination of rubidium atomic number densities in the range from about 5 x 10 16 cm -3 to 1 x 10 18 cm -3

  13. /sup 87/Rb NMR study at the cubic to tetragonal phase transition in RbCaF/sub 3/

    Energy Technology Data Exchange (ETDEWEB)

    Bulou, A [Angers Univ., 72 - Le Mans (France). Centre Universitaire; Theveneau, H; Trokiner, A; Papon, P [Ecole Superieure de Physique et Chimie Industrielles, 75 - Paris (France)

    1979-07-01

    The /sup 87/Rb nuclear magnetic resonance spectrum, in perovskite single crystal of RbCaF/sub 3/, is studied above and below the cubic-to-tetragonal phase transition occurring at 198 K. In the high-temperature cubic phase, the temperature dependence of the resonance line amplitude deviates from the Curie law and this can be attributed to the existence of tetragonal domains. In the low temperature tetragonal phase, a second-order quadrupole shift of the central line is observed, from which the CaF/sub 6/ tilt angle (order parameter) is derived. The order parameter temperature dependence is described by a power law with a cross over from exponent 0.5 to exponent 0.32 at 150 K. The tilt angle PHI is compared to the values obtained from X-ray and neutron powder diffraction data.

  14. A Measurement of $R_b$ using Mutually Exclusive Tags

    CERN Document Server

    Barate, R; Décamp, D; Ghez, P; Goy, C; Lees, J P; Lucotte, A; Minard, M N; Nief, J Y; Pietrzyk, B; Casado, M P; Chmeissani, M; Comas, P; Crespo, J M; Delfino, M C; Fernández, E; Fernández-Bosman, M; Garrido, L; Juste, A; Martínez, M; Miquel, R; Mir, L M; Orteu, S; Padilla, C; Park, I C; Pascual, A; Perlas, J A; Riu, I; Sánchez, F; Teubert, F; Colaleo, A; Creanza, D; De Palma, M; Gelao, G; Iaselli, Giuseppe; Maggi, G; Maggi, M; Marinelli, N; Nuzzo, S; Ranieri, A; Raso, G; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Tricomi, A; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Abbaneo, D; Alemany, R; Becker, U; Bazarko, A O; Bright-Thomas, P G; Cattaneo, M; Cerutti, F; Drevermann, H; Forty, Roger W; Frank, M; Hagelberg, R; Harvey, J; Janot, P; Jost, B; Kneringer, E; Knobloch, J; Lehraus, Ivan; Lutters, G; Mato, P; Minten, Adolf G; Moneta, L; Pacheco, A; Pusztaszeri, J F; Ranjard, F; Rensing, P E; Rizzo, G; Rolandi, Luigi; Schlatter, W D; Schmitt, M; Schneider, O; Tejessy, W; Tomalin, I R; Wachsmuth, H W; Wagner, A; Ajaltouni, Ziad J; Barrès, A; Boyer, C; Falvard, A; Ferdi, C; Gay, P; Guicheney, C; Henrard, P; Jousset, J; Michel, B; Monteil, S; Montret, J C; Pallin, D; Perret, P; Podlyski, F; Proriol, J; Rosnet, P; Rossignol, J M; Fearnley, Tom; Hansen, J B; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Rensch, B; Wäänänen, A; Daskalakis, G; Kyriakis, A; Markou, C; Simopoulou, Errietta; Siotis, I; Vayaki, Anna; Blondel, A; Bonneaud, G R; Brient, J C; Bourdon, P; Rougé, A; Rumpf, M; Valassi, Andrea; Verderi, M; Videau, H L; Candlin, D J; Parsons, M I; Focardi, E; Parrini, G; Zachariadou, K; Corden, M; Georgiopoulos, C H; Jaffe, D E; Antonelli, A; Bencivenni, G; Bologna, G; Bossi, F; Campana, P; Capon, G; Casper, David William; Chiarella, V; Felici, G; Laurelli, P; Mannocchi, G; Murtas, F; Murtas, G P; Passalacqua, L; Pepé-Altarelli, M; Curtis, L; Dorris, S J; Halley, A W; Knowles, I G; Lynch, J G; O'Shea, V; Raine, C; Scarr, J M; Smith, K; Teixeira-Dias, P; Thompson, A S; Thomson, E; Thomson, F; Turnbull, R M; Geweniger, C; Graefe, G; Hanke, P; Hansper, G; Hepp, V; Kluge, E E; Putzer, A; Schmidt, M; Sommer, J; Tittel, K; Werner, S; Wunsch, M; Beuselinck, R; Binnie, David M; Cameron, W; Dornan, Peter J; Girone, M; Goodsir, S M; Martin, E B; Moutoussi, A; Nash, J; Sedgbeer, J K; Stacey, A M; Williams, M D; Dissertori, G; Ghete, V M; Girtler, P; Kuhn, D; Rudolph, G; Betteridge, A P; Bowdery, C K; Colrain, P; Crawford, G; Finch, A J; Foster, F; Hughes, G; Sloan, Terence; Williams, M I; Galla, A; Giehl, I; Greene, A M; Hoffmann, C; Jakobs, K; Kleinknecht, K; Quast, G; Renk, B; Rohne, E; Sander, H G; Van Gemmeren, P; Zeitnitz, C; Aubert, Jean-Jacques; Benchouk, C; Bonissent, A; Bujosa, G; Calvet, D; Carr, J; Coyle, P; Diaconu, C A; Etienne, F; Konstantinidis, N P; Leroy, O; Motsch, F; Payre, P; Rousseau, D; Talby, M; Sadouki, A; Thulasidas, M; Trabelsi, K; Aleppo, M; Ragusa, F; Berlich, R; Blum, Walter; Brown, D; Büscher, V; Dietl, H; Dydak, Friedrich; Ganis, G; Gotzhein, C; Kroha, H; Lütjens, G; Lutz, Gerhard; Männer, W; Moser, H G; Richter, R H; Rosado-Schlosser, A; Schael, S; Settles, Ronald; Seywerd, H C J; Saint-Denis, R; Stenzel, H; Wiedenmann, W; Wolf, G; Boucrot, J; Callot, O; Chen, S; Choi, Y; Cordier, A; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Höcker, A; Jacholkowska, A; Jacquet, M; Kim, D W; Le Diberder, F R; Lefrançois, J; Lutz, A M; Nikolic, I A; Schune, M H; Simion, S; Tournefier, E; Veillet, J J; Videau, I; Zerwas, D; Azzurri, P; Bagliesi, G; Batignani, G; Bettarini, S; Bozzi, C; Calderini, G; Carpinelli, M; Ciocci, M A; Ciulli, V; Dell'Orso, R; Fantechi, R; Ferrante, I; Foà, L; Forti, F; Giassi, A; Giorgi, M A; Gregorio, A; Ligabue, F; Lusiani, A; Marrocchesi, P S; Messineo, A; Palla, Fabrizio; Sanguinetti, G; Sciabà, A; Spagnolo, P; Steinberger, Jack; Tenchini, Roberto; Tonelli, G; Vannini, C; Venturi, A; Verdini, P G; Blair, G A; Bryant, L M; Chambers, J T; Gao, Y; Green, M G; Medcalf, T; Perrodo, P; Strong, J A; Von Wimmersperg-Töller, J H; Botterill, David R; Clifft, R W; Edgecock, T R; Haywood, S; Maley, P; Norton, P R; Thompson, J C; Wright, A E; Bloch-Devaux, B; Colas, P; Emery, S; Kozanecki, Witold; Lançon, E; Lemaire, M C; Locci, E; Pérez, P; Rander, J; Renardy, J F; Roussarie, A; Schuller, J P; Schwindling, J; Trabelsi, A; Vallage, B; Black, S N; Dann, J H; Johnson, R P; Kim, H Y; Litke, A M; McNeil, M A; Taylor, G; Booth, C N; Boswell, R; Brew, C A J; Cartwright, S L; Combley, F; Kelly, M S; Lehto, M H; Newton, W M; Reeve, J; Thompson, L F; Böhrer, A; Brandt, S; Cowan, G D; Grupen, Claus; Saraiva, P; Smolik, L; Stephan, F; Apollonio, M; Bosisio, L; Della Marina, R; Giannini, G; Gobbo, B; Musolino, G; Rothberg, J E; Wasserbaech, S R; Armstrong, S R; Charles, E; Elmer, P; Ferguson, D P S; Gao, Y S; González, S; Greening, T C; Hayes, O J; Hu, H; Jin, S; McNamara, P A; Nachtman, J M; Nielsen, J; Orejudos, W; Pan, Y B; Saadi, Y; Scott, I J; Walsh, J; Wu Sau Lan; Wu, X; Yamartino, J M; Zobernig, G

    1997-01-01

    A measurement of $R_b$ using five mutually exclusive hemisphere tags has been pe rformed by ALEPH using the full LEP1 statistics. Three tags are designed to sele ct the decay of the $Z^0$ to $b$ quarks, while the remaining two select $Z^0$ decays to $c$ and light quarks, and are used to measure the tagging efficiencies. The result, {$R_b~=~0.2159~\\pm~0.0009\\mbox{(stat)}~\\pm 0.0011\\mbox{(syst)}$}, is in agreement with the electroweak theory prediction of $0.2158 \\pm 0.0003$.

  15. A measurement of Rb using a lifetime-mass tag

    Science.gov (United States)

    Barate, R.; Buskulic, D.; Decamp, D.; Ghez, P.; Goy, C.; Lees, J.-P.; Lucotte, A.; Minard, M.-N.; Nief, J.-Y.; Pietrzyk, B.; Casado, M. P.; Chmeissani, M.; Comas, P.; Crespo, J. M.; Delfino, M.; Fernandez, E.; Fernandez-Bosman, M.; Garrido, Ll.; Juste, A.; Martinez, M.; Miquel, R.; Mir, Ll. M.; Orteu, S.; Padilla, C.; Park, I. C.; Pascual, A.; Perlas, J. A.; Riu, I.; Sanchez, F.; Teubert, F.; Colaleo, A.; Creanza, D.; de Palma, M.; Gelao, G.; Iaselli, G.; Maggi, G.; Maggi, M.; Marinelli, N.; Nuzzo, S.; Ranieri, A.; Raso, G.; Ruggieri, F.; Selvaggi, G.; Silvestris, L.; Tempesta, P.; Tricomi, A.; Zito, G.; Huang, X.; Lin, J.; Ouyang, Q.; Wang, T.; Xie, Y.; Xu, R.; Xue, S.; Zhang, J.; Zhang, L.; Zhao, W.; Abbaneo, D.; Alemany, R.; Becker, U.; Bazarko, A. O.; Bright-Thomas, P.; Cattaneo, M.; Cerutti, F.; Drevermann, H.; Forty, R. W.; Frank, M.; Hagelberg, R.; Harvey, J.; Janot, P.; Jost, B.; Kneringer, E.; Knobloch, J.; Lehraus, I.; Lutters, G.; Mato, P.; Minten, A.; Moneta, L.; Pacheco, A.; Pusztaszeri, J.-F.; Ranjard, F.; Rensing, P.; Rizzo, G.; Rolandi, L.; Schlatter, D.; Schmitt, M.; Schneider, O.; Tejessy, W.; Tomalin, I. R.; Wachsmuth, H.; Wagner, A.; Ajaltouni, Z.; Barrès, A.; Boyer, C.; Falvard, A.; Ferdi, C.; Gay, P.; Guicheney, C.; Henrard, P.; Jousset, J.; Michel, B.; Monteil, S.; Montret, J.-C.; Pallin, D.; Perret, P.; Podlyski, F.; Proriol, J.; Rosnet, P.; Rossignol, J.-M.; Fearnley, T.; Hansen, J. B.; Hansen, J. D.; Hansen, J. R.; Hansen, P. H.; Nilsson, B. S.; Rensch, B.; Wäänänen, A.; Daskalakis, G.; Kyriakis, A.; Markou, C.; Simopoulou, E.; Siotis, I.; Vayaki, A.; Blondel, A.; Bonneaud, G.; Brient, J. C.; Bourdon, P.; Rougé, A.; Rumpf, M.; Valassi, A.; Verderi, M.; Videau, H.; Candlin, D. J.; Parsons, M. I.; Focardi, E.; Parrini, G.; Zachariadou, K.; Corden, M.; Georgiopoulos, C.; Jaffe, D. E.; Antonelli, A.; Bencivenni, G.; Bologna, G.; Bossi, F.; Campana, P.; Capon, G.; Casper, D.; Chiarella, V.; Felici, G.; Laurelli, P.; Mannocchi, G.; Murtas, F.; Murtas, G. P.; Passalacqua, L.; Pepe-Altarelli, M.; Curtis, L.; Dorris, S. J.; Halley, A. W.; Knowles, I. G.; Lynch, J. G.; O'Shea, V.; Raine, C.; Scarr, J. M.; Smith, K.; Teixeira-Dias, P.; Thompson, A. S.; Thomson, E.; Thomson, F.; Turnbull, R. M.; Geweniger, C.; Graefe, G.; Hanke, P.; Hansper, G.; Hepp, V.; Kluge, E. E.; Putzer, A.; Schmidt, M.; Sommer, J.; Tittel, K.; Werner, S.; Wunsch, M.; Beuselinck, R.; Binnie, D. M.; Cameron, W.; Dornan, P. J.; Girone, M.; Goodsir, S.; Martin, E. B.; Moutoussi, A.; Nash, J.; Sedgbeer, J. K.; Stacey, A. M.; Williams, M. D.; Dissertori, G.; Ghete, V. M.; Girtler, P.; Kuhn, D.; Rudolph, G.; Betteridge, A. P.; Bowdery, C. K.; Colrain, P.; Crawford, G.; Finch, A. J.; Foster, F.; Hughes, G.; Sloan, T.; Williams, M. I.; Galla, A.; Giehl, I.; Greene, A. M.; Hoffmann, C.; Jakobs, K.; Kleinknecht, K.; Quast, G.; Renk, B.; Rohne, E.; Sander, H.-G.; van Gemmeren, P.; Zeitnitz, C.; Aubert, J. J.; Benchouk, C.; Bonissent, A.; Bujosa, G.; Calvet, D.; Carr, J.; Coyle, P.; Diaconu, C.; Etienne, F.; Konstantinidis, N.; Leroy, O.; Motsch, F.; Payre, P.; Rousseau, D.; Talby, M.; Sadouki, A.; Thulasidas, M.; Trabelsi, K.; Aleppo, M.; Ragusa, F.; Berlich, R.; Blum, W.; Brown, D.; Büscher, V.; Dietl, H.; Dydak, F.; Ganis, G.; Gotzhein, C.; Kroha, H.; Lütjens, G.; Lutz, G.; Männer, W.; Moser, H.-G.; Richter, R.; Rosado-Schlosser, A.; Schael, S.; Settles, R.; Seywerd, H.; St. Denis, R.; Stenzel, H.; Wiedenmann, W.; Wolf, G.; Boucrot, J.; Callot, O.; Chen, S.; Choi, Y.; Cordier, A.; Davier, M.; Duflot, L.; Grivaz, J.-F.; Heusse, Ph.; Höcker, A.; Jacholkowska, A.; Jacquet, M.; Kim, D. W.; Le Diberder, F.; Lefrançois, J.; Lutz, A.-M.; Nikolic, I.; Schune, M.-H.; Simion, S.; Tournefier, E.; Veillet, J.-J.; Videau, I.; Zerwas, D.; Azzurri, P.; Bagliesi, G.; Batignani, G.; Bettarini, S.; Bozzi, C.; Calderini, G.; Carpinelli, M.; Ciocci, M. A.; Ciulli, V.; dell'Orso, R.; Fantechi, R.; Ferrante, I.; Foà, L.; Forti, F.; Giassi, A.; Giorgi, M. A.; Gregorio, A.; Ligabue, F.; Lusiani, A.; Marrocchesi, P. S.; Messineo, A.; Palla, F.; Sanguinetti, G.; Sciabà, A.; Spagnolo, P.; Steinberger, J.; Tenchini, R.; Tonelli, G.; Vannini, C.; Venturi, A.; Verdini, P. G.; Blair, G. A.; Bryant, L. M.; Chambers, J. T.; Gao, Y.; Green, M. G.; Medcalf, T.; Perrodo, P.; Strong, J. A.; von Wimmersperg-Toeller, J. H.; Botterill, D. R.; Clifft, R. W.; Edgecock, T. R.; Haywood, S.; Maley, P.; Norton, P. R.; Thompson, J. C.; Wright, A. E.; Bloch-Devaux, B.; Colas, P.; Emery, S.; Kozanecki, W.; Lançon, E.; Lemaire, M. C.; Locci, E.; Perez, P.; Rander, J.; Renardy, J.-F.; Roussarie, A.; Schuller, J.-P.; Schwindling, J.; Trabelsi, A.; Vallage, B.; Black, S. N.; Dann, J. H.; Johnson, R. P.; Kim, H. Y.; Litke, A. M.; McNeil, M. A.; Taylor, G.; Booth, C. N.; Boswell, R.; Brew, C. A. J.; Cartwright, S.; Combley, F.; Kelly, M. S.; Lehto, M.; Newton, W. M.; Reeve, J.; Thompson, L. F.; Böhrer, A.; Brandt, S.; Cowan, G.; Grupen, C.; Saraiva, P.; Smolik, L.; Stephan, F.; Apollonio, M.; Bosisio, L.; Della Marina, R.; Giannini, G.; Gobbo, B.; Musolino, G.; Rothberg, J.; Wasserbaech, S.; Armstrong, S. R.; Charles, E.; Elmer, P.; Ferguson, D. P. S.; Gao, Y. S.; González, S.; Greening, T. C.; Hayes, O. J.; Hu, H.; Jin, S.; McNamara, P. A.; Nachtman, J. M.; Nielsen, J.; Orejudos, W.; Pan, Y. B.; Saadi, Y.; Scott, I. J.; Walsh, J.; Wu, Sau Lan; Wu, X.; Yamartino, J. M.; Zobernig, G.

    1997-02-01

    ALEPH's published measurement of Rb = Γ(Z -> bb)/Γ(Z -> hadrons) using a lifetime tag is updated using the full LEP 1 data sample. Considerable effort has been devoted to understanding systematic effects. Charm background is better controlled by combining the lifetime tag with a tag based on the b/c hadron mass difference. Furthermore, the algorithm used to reconstruct the event primary vertex is designed so as to reduce correlations between the two hemispheres of an event. The value of Rb is measured to be 0.2167 +/- 0.0011 (stat) +/- 0.0013 (syst).

  16. Particle-phonon coupling in the odd-A Rb isotopes

    International Nuclear Information System (INIS)

    Krishan, K.; Basu, S.K.; Sen, S.

    1976-01-01

    The level properties of 83 Rb and 85 Rb have been calculated in a quasiparticle-phonon coupling model which couples the proton quasiparticle motion in the 1fsub(5/2), 2psub(1/2), 2psub(3/2) and 1gsub(9/2) orbitals to the vibrations of the neighbouring even core. The calculated level spectra, spectroscopic factors and B(E2) values for several levels are found to be in good agreement with available experimental data. Branching ratios for transitions originating from several levels are also reproduced. (author)

  17. Rb*Hen exciplexes in solid 4He

    International Nuclear Information System (INIS)

    Hofer, A.; Moroshkin, P.; Nettels, D.; Ulzega, S.; Weis, A.

    2006-01-01

    We report the observation of emission spectra from Rb*He n exciplexes in solid 4 He. Two different excitation channels were experimentally identified, viz., exciplex formation via laser excitation to the atomic 5P 3/2 and to the 5P 1/2 levels. While the former channel was observed before in liquid helium, on helium nanodroplets, and in helium gas by different groups, the latter creation mechanism occurs only in solid helium or in gaseous helium above 10 K. The experimental results are compared to theoretical predictions based on the extension of a model, used earlier by us for the description of Cs*He n exciplexes. We also report the observation of fluorescence from atomic rubidium in solid helium, and discuss striking differences between the spectroscopic features of Rb-He and Cs-He systems

  18. Cloning and Molecular Characterization of the Schistosoma mansoni Genes RbAp48 and Histone H4

    Directory of Open Access Journals (Sweden)

    Patrícia P Souza

    2002-10-01

    Full Text Available The human nuclear protein RbAp48 is a member of the tryptophan/aspartate (WD repeat family, which binds to the retinoblastoma (Rb protein. It also corresponds to the smallest subunit of the chromatin assembly factor and is able to bind to the helix 1 of histone H4, taking it to the DNA in replication. A cDNA homologous to the human gene RbAp48 was isolated from a Schistosoma mansoni adult worm library and named SmRbAp48. The full length sequence of SmRbAp48 cDNA is 1036 bp long, encoding a protein of 308 amino acids. The transcript of SmRbAp48 was detected in egg, cercariae and schistosomulum stages. The protein shows 84% similarity with the human RbAp48, possessing four WD repeats on its C-terminus. A hypothetical tridimensional structure for the SmRbAp48 C-terminal domain was constructed by computational molecular modeling using the b-subunit of the G protein as a model. To further verify a possible interaction between SmRbAp48 and S. mansoni histone H4, the histone H4 gene was amplified from adult worm genomic DNA using degenerated primers. The gene fragment of SmH4 is 294 bp long, encoding a protein of 98 amino acids which is 100% identical to histone H4 from Drosophila melanogaster.

  19. Phase formation in the Li2MoO4-Rb2MoO4-Ln2(MoO4)3 systems and the properties of LiRbLn2(MoO4)4

    International Nuclear Information System (INIS)

    Basovich, O.M.; Khajkina, E.G.; Vasil'ev, E.V.; Frolov, A.M.

    1995-01-01

    Phase equilibria within subsolidus range of ternary salt systems Li 2 MoO 4 -Rb 2 MoO 4 -Ln 2 (MoO 4 ) 4 (Ln - Nd, Er) are analyzed. Formation of ternary molybdate LiRbNd 2 (MoO 4 ) 4 is proved along LiNd(MoO 4 ) 2 -RbNd(MoO 4 )-2 cross-section. Phase diagram of this cross-section is plotted. Similar compounds are synthesized for Ln = La-Eu. The parameters of their monoclinic elementary cells are determined. Luminescent properties of LiRbLa 2 (MoO 4 ) 4 -Nd 3+ are studied. 17 refs., 4 figs., 2 tabs

  20. Spin-interaction effects for ultralong-range Rydberg molecules in a magnetic field

    Science.gov (United States)

    Hummel, Frederic; Fey, Christian; Schmelcher, Peter

    2018-04-01

    We investigate the fine and spin structure of ultralong-range Rydberg molecules exposed to a homogeneous magnetic field. Each molecule consists of a 87Rb Rydberg atom the outer electron of which interacts via spin-dependent s - and p -wave scattering with a polarizable 87Rb ground-state atom. Our model includes also the hyperfine structure of the ground-state atom as well as spin-orbit couplings of the Rydberg and ground-state atom. We focus on d -Rydberg states and principal quantum numbers n in the vicinity of 40. The electronic structure and vibrational states are determined in the framework of the Born-Oppenheimer approximation for varying field strengths ranging from a few up to hundred Gauss. The results show that the interplay between the scattering interactions and the spin couplings gives rise to a large variety of molecular states in different spin configurations as well as in different spatial arrangements that can be tuned by the magnetic field. This includes relatively regularly shaped energy surfaces in a regime where the Zeeman splitting is large compared to the scattering interaction but small compared to the Rydberg fine structure, as well as more complex structures for both weaker and stronger fields. We quantify the impact of spin couplings by comparing the extended theory to a spin-independent model.

  1. RB reactor benchmark cores

    International Nuclear Information System (INIS)

    Pesic, M.

    1998-01-01

    A selected set of the RB reactor benchmark cores is presented in this paper. The first results of validation of the well-known Monte Carlo MCNP TM code and adjoining neutron cross section libraries are given. They confirm the idea for the proposal of the new U-D 2 O criticality benchmark system and support the intention to include this system in the next edition of the recent OECD/NEA Project: International Handbook of Evaluated Criticality Safety Experiment, in near future. (author)

  2. 75 FR 27973 - Airworthiness Directives; Rolls-Royce plc RB211-524C2 Series Turbofan Engines

    Science.gov (United States)

    2010-05-19

    ... RB211-524C2 Series Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice... Rolls-Royce plc (RR) model RB211-524C2-19 and RB211-524C2-B-19 turbofan engines. These engines are...

  3. Luminescence and scintillation properties of Rb2HfCl6 crystals

    International Nuclear Information System (INIS)

    Saeki, Keiichiro; Wakai, Yuki; Fujimoto, Yutaka; Koshimizu, Masanori; Asai, Keisuke; Yanagida, Takayuki; Nakauchi, Daisuke

    2016-01-01

    We developed a scintillator based on a Rb 2 HfCl 6 crystal as a ternary halide crystal with intrinsic luminescence. In the photoluminescence spectra, two emission bands are observed at 383 and 434 nm. The 434 nm emission band for Rb 2 HfCl 6 may be attributed to [HfCl 6 ] 2- complex ion or [ZrCl 6 ] 2- impurity, since the Rb 2 HfCl 6 contained Zr as impurity at 0.62 mol %. The radioluminescence band is observed at 420 nm and can be attributed to the same origin as the photoluminescence band at 434 nm. The scintillation decay-time constants were 0.84 and 5.4 μs. The light yield was estimated to be 24,100 photons/MeV. (author)

  4. Immune responses of bison and efficacy after booster vaccination with Brucella abortus strain RB51

    Science.gov (United States)

    Thirty-one bison heifers were randomly assigned to saline (control; n=7) or single vaccination (n=24) with 1010 CFU of B. abortus strain RB51 (RB51). Some vaccinated bison were randomly selected for booster vaccination with 10**10 CFU of RB51 at 11 months after initial vaccination (n=16). When comp...

  5. The role of p53 and pRB in apoptosis and cancer

    DEFF Research Database (Denmark)

    Hickman, Emma S; Moroni, M Cristina; Helin, Kristian

    2002-01-01

    Loss of function of both the p53 pathway and the retinoblastoma protein (pRB) pathway plays a significant role in the development of most human cancers. Loss of pRB results in deregulated cell proliferation and apoptosis, whereas loss of p53 desensitizes cells to checkpoint signals, including...

  6. Photodissociation of ultracold diatomic strontium molecules with quantum state control.

    Science.gov (United States)

    McDonald, M; McGuyer, B H; Apfelbeck, F; Lee, C-H; Majewska, I; Moszynski, R; Zelevinsky, T

    2016-07-07

    Chemical reactions at ultracold temperatures are expected to be dominated by quantum mechanical effects. Although progress towards ultracold chemistry has been made through atomic photoassociation, Feshbach resonances and bimolecular collisions, these approaches have been limited by imperfect quantum state selectivity. In particular, attaining complete control of the ground or excited continuum quantum states has remained a challenge. Here we achieve this control using photodissociation, an approach that encodes a wealth of information in the angular distribution of outgoing fragments. By photodissociating ultracold (88)Sr2 molecules with full control of the low-energy continuum, we access the quantum regime of ultracold chemistry, observing resonant and nonresonant barrier tunnelling, matter-wave interference of reaction products and forbidden reaction pathways. Our results illustrate the failure of the traditional quasiclassical model of photodissociation and instead are accurately described by a quantum mechanical model. The experimental ability to produce well-defined quantum continuum states at low energies will enable high-precision studies of long-range molecular potentials for which accurate quantum chemistry models are unavailable, and may serve as a source of entangled states and coherent matter waves for a wide range of experiments in quantum optics.

  7. Zebrafish usp39 mutation leads to rb1 mRNA splicing defect and pituitary lineage expansion.

    Directory of Open Access Journals (Sweden)

    Yesenia Ríos

    2011-01-01

    Full Text Available Loss of retinoblastoma (Rb tumor suppressor function is associated with human malignancies. Molecular and genetic mechanisms responsible for tumorigenic Rb downregulation are not fully defined. Through a forward genetic screen and positional cloning, we identified and characterized a zebrafish ubiquitin specific peptidase 39 (usp39 mutation, the yeast and human homolog of which encodes a component of RNA splicing machinery. Zebrafish usp39 mutants exhibit microcephaly and adenohypophyseal cell lineage expansion without apparent changes in major hypothalamic hormonal and regulatory signals. Gene expression profiling of usp39 mutants revealed decreased rb1 and increased e2f4, rbl2 (p130, and cdkn1a (p21 expression. Rb1 mRNA overexpression, or antisense morpholino knockdown of e2f4, partially reversed embryonic pituitary expansion in usp39 mutants. Analysis of pre-mRNA splicing status of critical cell cycle regulators showed misspliced Rb1 pre-mRNA resulting in a premature stop codon. These studies unravel a novel mechanism for rb1 regulation by a neuronal mRNA splicing factor, usp39. Zebrafish usp39 regulates embryonic pituitary homeostasis by targeting rb1 and e2f4 expression, respectively, contributing to increased adenohypophyseal sensitivity to these altered cell cycle regulators. These results provide a mechanism for dysregulated rb1 and e2f4 pathways that may result in pituitary tumorigenesis.

  8. Hamilton's inclusive fitness maintains heritable altruism polymorphism through rb = c.

    Science.gov (United States)

    Wang, Changcao; Lu, Xin

    2018-02-20

    How can altruism evolve or be maintained in a selfish world? Hamilton's rule shows that the former process will occur when rb > c -the benefits to the recipients of an altruistic act b , weighted by the relatedness between the social partners r , exceed the costs to the altruists c -drives altruistic genotypes spreading against nonaltruistic ones. From this rule, we infer that altruistic genotypes will persist in a population by forming a stable heritable polymorphism with nonaltruistic genotypes if rb = c makes inclusive fitness of the two morphs equal. We test this prediction using the data of 12 years of study on a cooperatively breeding bird, the Tibetan ground tit Pseudopodoces humilis , where helping is performed by males only and kin-directed. Individual variation in ever acting as a helper was heritable ( h 2 = 0.47), and the resultant altruism polymorphism remained stable as indicated by low-level annual fluctuation of the percentage of helpers among all adult males (24-28%). Helpers' indirect fitness gains from increased lifetime reproductive success of related breeders statistically fully compensated for their lifetime direct fitness losses, suggesting that rb = c holds. While our work provides a fundamental support for Hamilton's idea, it highlights the equivalent inclusive fitness returns to altruists and nonaltruists mediated by rb = c as a theoretically and realistically important mechanism to maintain social polymorphism.

  9. Brucella abortus Strain RB51 Vaccine: Immune Response after Calfhood Vaccination and Field Investigation in Italian Cattle Population

    Directory of Open Access Journals (Sweden)

    Manuela Tittarelli

    2008-01-01

    Full Text Available Immune response to Brucella abortus strain RB51 vaccine was measured in cattle vaccinated at calfhood. After an increase at day 6 post-vaccination (pv, the antibody level recorded in the 10 vaccinated animals remained constant for two months, and then progressively decreased. All vaccinated animals remained negative from day 162 pv to the end of the study (day 300 pv. Only at days 13 and 14 pv the RB51-CFT showed 100% sensitivity (credibility interval (CI 76.2%–100%. The results indicate that the possibility to use RB51-CFT for the identification of cattle vaccinated at calfhood with RB51 is limited in time. A field investigation was carried out on 26,975 sera collected on regional basis from the Italian cattle population. The study outcomes indicate that in case of RB51-CFT positive results observed in officially Brucellosis-free (OBF areas and, in any case, when an illegal use of RB51 vaccine is suspected, the use of the RB51-CFT alone is not sufficient to identify all the vaccinated animals. The design of a more sophisticated diagnostic protocol including an epidemiological investigation, the use of RB51-CFT, and the use of the skin test with RB51 as antigen is deemed more appropriate for the identification of RB51 vaccinated animals.

  10. Rb suppresses collective invasion, circulation and metastasis of breast cancer cells in CD44-dependent manner.

    Directory of Open Access Journals (Sweden)

    Kui-Jin Kim

    Full Text Available Basal-like breast carcinomas (BLCs present with extratumoral lymphovascular invasion, are highly metastatic, presumably through a hematogenous route, have augmented expression of CD44 oncoprotein and relatively low levels of retinoblastoma (Rb tumor suppressor. However, the causal relation among these features is not clear. Here, we show that Rb acts as a key suppressor of multiple stages of metastatic progression. Firstly, Rb suppresses collective cell migration (CCM and CD44-dependent formation of F-actin positive protrusions in vitro and cell-cluster based lymphovascular invasion in vivo. Secondly, Rb inhibits the release of single cancer cells and cell clusters into the hematogenous circulation and subsequent metastatic growth in lungs. Finally, CD44 expression is required for collective motility and all subsequent stages of metastatic progression initiated by loss of Rb function. Altogether, our results suggest that Rb/CD44 pathway is a crucial regulator of CCM and metastatic progression of BLCs and a promising target for anti-BLCs therapy.

  11. ATM Mediates pRB Function To Control DNMT1 Protein Stability and DNA Methylation

    Science.gov (United States)

    Suzuki, Misa; Hayashi, Naoyuki; Kobayashi, Masahiko; Sasaki, Nobunari; Nishiuchi, Takumi; Doki, Yuichiro; Okamoto, Takahiro; Kohno, Susumu; Muranaka, Hayato; Kitajima, Shunsuke; Yamamoto, Ken-ichi

    2013-01-01

    The retinoblastoma tumor suppressor gene (RB) product has been implicated in epigenetic control of gene expression owing to its ability to physically bind to many chromatin modifiers. However, the biological and clinical significance of this activity was not well elucidated. To address this, we performed genetic and epigenetic analyses in an Rb-deficient mouse thyroid C cell tumor model. Here we report that the genetic interaction of Rb and ATM regulates DNMT1 protein stability and hence controls the DNA methylation status in the promoters of at least the Ink4a, Shc2, FoxO6, and Noggin genes. Furthermore, we demonstrate that inactivation of pRB promotes Tip60 (acetyltransferase)-dependent ATM activation; allows activated ATM to physically bind to DNMT1, forming a complex with Tip60 and UHRF1 (E3 ligase); and consequently accelerates DNMT1 ubiquitination driven by Tip60-dependent acetylation. Our results indicate that inactivation of the pRB pathway in coordination with aberration in the DNA damage response deregulates DNMT1 stability, leading to an abnormal DNA methylation pattern and malignant progression. PMID:23754744

  12. Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo.

    Science.gov (United States)

    Ehmer, Ursula; Zmoos, Anne-Flore; Auerbach, Raymond K; Vaka, Dedeepya; Butte, Atul J; Kay, Mark A; Sage, Julien

    2014-07-24

    In mammals, a cell's decision to divide is thought to be under the control of the Rb/E2F pathway. We previously found that inactivation of the Rb family of cell cycle inhibitors (Rb, p107, and p130) in quiescent liver progenitors leads to uncontrolled division and cancer initiation. Here, we show that, in contrast, deletion of the entire Rb gene family in mature hepatocytes is not sufficient for their long-term proliferation. The cell cycle block in Rb family mutant hepatocytes is independent of the Arf/p53/p21 checkpoint but can be abrogated upon decreasing liver size. At the molecular level, we identify YAP, a transcriptional regulator involved in organ size control, as a factor required for the sustained expression of cell cycle genes in hepatocytes. These experiments identify a higher level of regulation of the cell cycle in vivo in which signals regulating organ size are dominant regulators of the core cell cycle machinery. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  13. Rb and p53 gene deletions in lung adenocarcinomas from irradiated and control mice

    International Nuclear Information System (INIS)

    Zhang, Y.; Woloschak, G.E.

    1997-01-01

    This study was conducted on mouse lung adenocarcinoma tissues that were formalin-treated and paraffin-embedded 25 years ago to investigate the large gene deletions of mRb and p53 in B6CF 1 male mice. A total of 80 lung tissue samples from irradiated mice and 40 lung samples from nonirradiated controls were randomly selected and examined in the mRb portion of this study. The results showed a significant (P 0.05) from that for spontaneous lung adenocarcinomas or lung adenocarcinomas from mice exposed to single-dose γ irradiation at a similar total dose. mRb fragments 3 (71%) and 5 (67%), the parts of the gene that encoded the pocket binding region of Rb protein to adenovirus E1A and SV40 T-antigen, were the most frequently deleted fragments. p53 gene deletion analysis was carried out on normal lungs and lung adenocarcinomas that were initially found to bear mRb deletions. Exons 1,4,5,6, and 9 were chosen to be analyzed

  14. Eu and Rb co-doped LiCaAlF6 scintillators for neutron detection

    International Nuclear Information System (INIS)

    Yamaji, Akihiro; Yanagida, Takayuki; Kawaguchi, Noriaki; Yokota, Yuui; Fujimoto, Yutaka; Kurosawa, Shunsuke; Pejchal, Jan; Watanabe, Kenichi; Yamazaki, Atsushi; Yoshikawa, Akira

    2013-01-01

    Eu and Rb co-doped LiCaAlF 6 (LiCAF) single crystals with different dopant concentrations were grown by the micro-pulling-down method for neutron detection. Their transmittance spectra showed strong absorption bands at 200–220 and 290–350 nm, and under 241 Am alpha-ray excitation, their radioluminescence spectra exhibited an intense emission peak at 373 nm that was attributed to the Eu 2+ 5d–4f transition. These results were consistent with those for the Rb-free Eu:LiCAF. The highest light yield among the grown crystals was 36,000 ph/n, which was 20% greater than that of the Rb-free crystal. In addition, the neutron-excited scintillation decay times were 650–750 ns slower than that of the Rb-free Eu:LiCAF. -- Highlights: •Eu and Rb co-doped LiCaAlF 6 crystals were grown by the micro-pulling down method. •Transmittance, photoluminescence and radioluminescence spectra were measured. •The light yields and scintillation decays were evaluated under 252 Cf neutron irradiation

  15. Functional ablation of pRb activates Cdk2 and causes antiestrogen resistance in human breast cancer cells.

    Directory of Open Access Journals (Sweden)

    Hemant Varma

    2007-12-01

    Full Text Available Estrogens are required for the proliferation of hormone dependent breast cancer cells, making estrogen receptor (ER positive tumors amenable to endocrine therapies such as antiestrogens. However, resistance to these agents remains a significant cause of treatment failure. We previously demonstrated that inactivation of the retinoblastoma protein (pRb family tumor suppressors causes antiestrogen resistance in MCF-7 cells, a widely studied model of estrogen responsive human breast cancers. In this study, we investigate the mechanism by which pRb inactivation leads to antiestrogen resistance. Cdk4 and cdk2 are two key cell cycle regulators that can phosphorylate and inactivate pRb, therefore we tested whether these kinases are required in cells lacking pRb function. pRb family members were inactivated in MCF-7 cells by expressing polyomavirus large tumor antigen (PyLT, and cdk activity was inhibited using the cdk inhibitors p16(INK4A and p21(Waf1/Cip1. Cdk4 activity was no longer required in cells lacking functional pRb, while cdk2 activity was required for proliferation in both the presence and absence of pRb function. Using inducible PyLT cell lines, we further demonstrated that pRb inactivation leads to increased cyclin A expression, cdk2 activation and proliferation in antiestrogen arrested cells. These results demonstrate that antiestrogens do not inhibit cdk2 activity or proliferation of MCF-7 cells in the absence of pRb family function, and suggest that antiestrogen resistant breast cancer cells resulting from pRb pathway inactivation would be susceptible to therapies that target cdk2.

  16. BRCA1: RB Interaction in Breast Cancer Suppression

    National Research Council Canada - National Science Library

    Fan, Saijun

    2000-01-01

    .... Recent studies suggest that the tumor suppressor activity of BRCAl is due, in part, to physical/functional interactions with other tumor suppressors, including p53 and the retinoblastoma (RB) protein...

  17. BRCA1: RB Interaction in Breast Cancer Suppression

    National Research Council Canada - National Science Library

    Fan, Saijun

    2001-01-01

    .... Recent studies suggest that the tumor suppressor activity of BRCAl is due, in part, to physical/functional interactions with other tumor suppressors, including p53 and the retinoblastoma (RB) protein...

  18. Phase equilibrium in the AgI-RbI-H2O system at 25 deg C

    International Nuclear Information System (INIS)

    Stepin, B.D.; Serebrennikova, G.M.; Sazikova, L.A.; Starikova, Z.A.

    1977-01-01

    The triple system of AgI-RbI-H 2 O at 25 deg C was studied by the isothermal method. The formation of the Rb 2 AgI 3 complex compound, which dissolves in water with decomposition, was established. A powder pattern of Rb 2 AgI 3 was indexed

  19. Purification of cyclotron-produced 81Rb for the preparation of small krypton-81m generators

    International Nuclear Information System (INIS)

    Andersen, P.; Haasbroek, F.J.; Venter, S.S.J.; Strelow, F.W.E.

    1981-01-01

    A method is described for the separation of 81 Rb from sodium bromide targets. Ammonium molybdophosphate columns are used and the separation takes only about 20 minutes. More than 90% of the 81 Rb is recovered. The purified 81 Rb enables small Rubidium-81/Krypton-81m generators to be prepared with Bio-Rad 50W-X8 ion-exchange resin (200-400 mesh) [af

  20. Scattering amplitude of ultracold atoms near the p-wave magnetic Feshbach resonance

    International Nuclear Information System (INIS)

    Zhang Peng; Naidon, Pascal; Ueda, Masahito

    2010-01-01

    Most of the current theories on the p-wave superfluid in cold atomic gases are based on the effective-range theory for the two-body scattering, where the low-energy p-wave scattering amplitude f 1 (k) is given by f 1 (k)=-1/[ik+1/(Vk 2 )+1/R]. Here k is the incident momentum, V and R are the k-independent scattering volume and effective range, respectively. However, due to the long-range nature of the van der Waals interaction between two colliding ultracold atoms, the p-wave scattering amplitude of the two atoms is not described by the effective-range theory [J. Math. Phys. 4, 54 (1963); Phys. Rev. A 58, 4222 (1998)]. In this paper we provide an explicit calculation for the p-wave scattering of two ultracold atoms near the p-wave magnetic Feshbach resonance. We show that in this case the low-energy p-wave scattering amplitude f 1 (k)=-1/[ik+1/(V eff k 2 )+1/(S eff k)+1/R eff ] where V eff , S eff , and R eff are k-dependent parameters. Based on this result, we identify sufficient conditions for the effective-range theory to be a good approximation of the exact scattering amplitude. Using these conditions we show that the effective-range theory is a good approximation for the p-wave scattering in the ultracold gases of 6 Li and 40 K when the scattering volume is enhanced by the resonance.

  1. Partial cross sections for Rb- photodetachment in the region of the Rb(5p2Psub(1/2,3/2)) thresholds and their analysis by multichannel quantum defect theory

    International Nuclear Information System (INIS)

    Frey, P.; Lawen, M.; Breyer, F.; Klar, H.; Hotop, H.

    1982-01-01

    A crossed ion-laser beam apparatus has been used to measure accurate relative total and partial cross sections for photodetachment from Rb - ions with high photon energy resolution (0.1-0.6 cm -1 ) in the region of the Rb(5p 2 Psub(1/2,3/2)) thresholds (photon energy range 16.350-16.820 cm -1 ). Satisfactory fits to these data by multichannel quantum defect theory (MQDT) have been obtained, resulting in a reliable set of seven MQDT parameters. The electron angular distribution parameter for the Rb(5s) channel was found to be β(5s)=2, independent of photon energy, MQDT predicts a sharp, window-type variation of β(5s) around the minimum of the 5s-cross section below the Rb(5p 2 Psub(1/2)) threshold (where an accurate experimental measurement of β(5s) was not possible) and a similar behaviour of β(6s) in the case of Cs - photodetachment below the Cs(6p 2 Psub(1/2)) threshold. (orig.)

  2. Topologically identical, but geometrically isomeric layers in hydrous α-, β-Rb[UO2(AsO3OH)(AsO2(OH)2)]·H2O and anhydrous Rb[UO2(AsO3OH)(AsO2(OH)2)

    International Nuclear Information System (INIS)

    Yu, Na; Klepov, Vladislav V.; Villa, Eric M.; Bosbach, Dirk; Suleimanov, Evgeny V.; Depmeier, Wulf; Albrecht-Schmitt, Thomas E.; Alekseev, Evgeny V.

    2014-01-01

    The hydrothermal reaction of uranyl nitrate with rubidium nitrate and arsenic (III) oxide results in the formation of polymorphic α- and β-Rb[UO 2 (AsO 3 OH)(AsO 2 (OH) 2 )]·H 2 O (α-, β-RbUAs) and the anhydrous phase Rb[UO 2 (AsO 3 OH)(AsO 2 (OH) 2 )] (RbUAs). These phases were structurally, chemically and spectroscopically characterized. The structures of all three compounds are based upon topologically identical, but geometrically isomeric layers. The layers are linked with each other by means of the Rb cations and hydrogen bonding. Dehydration experiments demonstrate that water deintercalation from hydrous α- and β-RbUAs yields anhydrous RbUAs via topotactic reactions. - Graphical abstract: Three different layer geometries observed in the structures of Rb[UO 2 (AsO 3 OH)(AsO 2 (OH) 2 )] and α- and β- Rb[UO 2 (AsO 3 OH)(AsO 2 (OH) 2 )]·H 2 O. Two different coordination environments of uranium polyhedra (types I and II) are shown schematically on the top of the figure. - Highlights: • Three new uranyl arsenates were synthesized from the hydrothermal reactions. • The phases consist of the topologically identical but geometrically different layers. • Topotactic transitions were observed in the processes of mono-hyrates dehydration

  3. Lead Discovery for Alzheimer’s Disease Related Target Protein RbAp48 from Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Hung-Jin Huang

    2014-01-01

    Full Text Available Deficiency or loss of function of Retinoblastoma-associated proteins (RbAp48 is related with Alzheimer’s disease (AD, and AD disease is associated with age-related memory loss. During normal function, RbAp48 forms a complex with the peptide FOG-1 (friend of GATA-1 and has a role in gene transcription, but an unstable complex may affect the function of RbAp48. This study utilizes the world’s largest traditional Chinese medicine (TCM database and virtual screening to provide potential compounds for RbAp48 binding. A molecular dynamics (MD simulation was employed to understand the variations after protein-ligand interaction. FOG1 was found to exhibit low stability after RbAp48 binding; the peptide displayed significant movement from the initial docking position, a phenomenon which matched the docking results. The protein structure of the other TCM candidates was not variable during MD simulation and had a greater stable affinity for RbAp48 binding than FOG1. Our results reveal that the protein structure does not affect ligand binding, and the top three TCM candidates Bittersweet alkaloid II, Eicosandioic acid, and Perivine might resolve the instability of the RbAp48-FOG1 complex and thus be used in AD therapy.

  4. Single cell analysis of G1 check points-the relationship between the restriction point and phosphorylation of pRb

    International Nuclear Information System (INIS)

    Martinsson, Hanna-Stina; Starborg, Maria; Erlandsson, Fredrik; Zetterberg, Anders

    2005-01-01

    Single cell analysis allows high resolution investigation of temporal relationships between transition events in G 1 . It has been suggested that phosphorylation of the retinoblastoma tumor suppressor protein (pRb) is the molecular mechanism behind passage through the restriction point (R). We performed a detailed single cell study of the temporal relationship between R and pRb phosphorylation in human fibroblasts using time lapse video-microscopy combined with immunocytochemistry. Four principally different criteria for pRb phosphorylation were used, namely (i) phosphorylation of residues Ser 795 and Ser 780 (ii) degree of pRb-association with the nuclear structure, a property that is closely related with pRb phosphorylation status, (iii) release of the transcription factor E2F-1 from pRb, and (iv) accumulation of cyclin E, which is dependent on phosphorylation of pRb. The analyses of individual cells revealed that passage through R preceded phosphorylation of pRb, which occurs in a gradually increasing proportion of cells in late G 1 . Our data clearly suggest that pRb phosphorylation is not the molecular mechanism behind the passage through R. The restriction point and phosphorylation of pRb thus seem to represent two separate check point in G 1

  5. The collision cross sections for excitation energy transfer in Rb*(5P3/2)+K(4S1/2)→Rb(5S1/2)+K*(4PJ) processes

    International Nuclear Information System (INIS)

    Horvatic, V.; Vadla, C.; Movre, M.

    1993-01-01

    The collisional excitation transfer for the processes Rb * (5P 3/2 ) + K(4S 1/2 ) → Rb(5S 1/2 ) + K * (4P J ), J = 1/2, 3/2, was investigated using two-photon laser excitation techniques with a thermionic heat-pipe diode as a detector. The population densities of the K 4P J levels induced by collisions with excited Rb atoms as well as those produced by direct laser excitation of the potassium atoms were probed through the measurement of the thermionic signals generated due to the ionization of the potassium atoms emerging from the K(4P J ) → K(7S 1/2 ) excitation channel. (orig./WL)

  6. 26Al(n,p)26Mg reaction: Comparison between the Hauser-Feshbach formula and the exact random-matrix result for the cross section

    International Nuclear Information System (INIS)

    Thomas, J.; Zirnbauer, M.R.; Langanke, K.

    1986-01-01

    We have calculated the 26 Al(n,p) 26 Mg reaction rate using an exact expression for the compound-nucleus cross section derived recently by Verbaarschot et al. This reaction is astrophysically important, and it happens to fall in a kinematic regime where the exact expression is expected to yield large deviations from the standard Hauser-Feshbach formula. We find that the exact statistical cross section is 20% lower at energies greater than 300 keV, and drops to 40% lower at 0 energy but still does not describe the available data. These deviations are quite similar to those predicted by the formula of Tepel et al

  7. Documents needed for obtaining the operation licence for the HERBE system at the RB reactor; Dokumentacija za dobijanje dozvole za rad sistema HERBE na reaktoru RB

    Energy Technology Data Exchange (ETDEWEB)

    Pesic, M et al [Boris Kidric Institute of Nuclear Sciences Vinca, Belgrade (Yugoslavia)

    1989-10-15

    Documents included in this volume are needed for obtaining the operation licence for the coupled fast-thermal system HERBE constructed at the RB reactor. It contains the following chapters: description of the system; nuclear calculations; performed changes at the RB reactor; proofs about static and dynamic stability of the built construction; normal operation regime of HERBE; accident analysis; dosimetry data; additional instructions and regulations for reactor operation; program of start-up; program for testing the HERBE system.

  8. K-Ca and Rb-Sr Dating of Lunar Granite 14321 Revisited

    Science.gov (United States)

    Simon, Justin I.; Shih, C.-Y.; Nyquist, L. E.

    2011-01-01

    K-Ca and Rb-Sr age determinations were made for a bulk feldspar-rich portion of an Apollo rock fragment of the pristine lunar granite clast (14321,1062), an acid-leached split of the sample, and the leachate. K-Ca and Rb-Sr data were also obtained for a whole rock sample of Apollo ferroan anorthosite (FAN, 15415). The recent detection [1] of widespread intermediate composition plagioclase indicates that the generation of a diversity of evolved lunar magmas maybe more common and therefore more important to our understanding of crust formation than previously believed. Our new data strengthen the K-Ca and Rb-Sr internal isochrons of the well-studied Apollo sample 14321 [2], which along with a renewed effort to study evolved lunar magmas will provide an improved understanding of the petrogenetic history of evolved rocks on the Moon.

  9. A Faraday laser lasing on Rb 1529 nm transition.

    Science.gov (United States)

    Chang, Pengyuan; Peng, Huanfa; Zhang, Shengnan; Chen, Zhangyuan; Luo, Bin; Chen, Jingbiao; Guo, Hong

    2017-08-21

    We present the design and performance characterization of a Faraday laser directly lasing on the Rb 1529 nm transition (Rb, 5P 3/2  - 4D 5/2 ) with high stability, narrow spectral linewidth and low cost. This system does not need an additional frequency-stabilized pump laser as a prerequisite to preparing Rb atom from 5S to 5P excited state. Just by using a performance-improved electrodeless discharge lamp-based excited-state Faraday anomalous dispersion optical filter (LESFADOF), we realized a heterogeneously Faraday laser with the frequency corresponding to atomic transition, working stably over a range of laser diode (LD) current from 85 mA to 171 mA and the LD temperature from 11 °C to 32 °C, as well as the 24-hour long-term frequency fluctuation range of no more than 600 MHz. Both the laser linewidth and relative intensity noisy (RIN) are measured. The Faraday laser lasing on Rb 1529 nm transition (telecom C-band) can be applied to further research on metrology, microwave photonics and optical communication systems. Besides, since the transitions correspongding to the populated excited-states of alkali atoms within lamp are extraordinarily rich, this scheme can increase the flexibility for choosing proper wavelengths for Faraday laser and greatly expand the coverage of wavelength corresponding to atomic transmission for laser frequency stabilization.

  10. Gamma monitoring system 'Hyperion' at the research nuclear reactor RB

    International Nuclear Information System (INIS)

    Zigic, A.; Saponjic, Dj.; Arandelovic, V. . E-mail address of corresponding author: alex@vin.bg.ac.yu

    2005-01-01

    While performing experiments at the research reactor RB at Vinca institute it is mandatory to measure the intensity of gamma radiation at reactor RB since the reactor has no biological protection. the stationary distributed measurement system 'Hyperion' implemented at reactor RB, performs measurements and monitoring of gamma radiation at 10 specified measuring sites within and in the vicinity of the reactor RB in the required absorbed dose in air range of 50 nGy/h to 10 mGy/h. the 'Hyperion' monitoring system have three hierarchically organized layers. the basic layer consists of the network of 10 intelligent gm probes located at predetermined measuring sites. the medium layer represents the PC-based local control node where measured data from all intelligent probes are separately acquired, stored in the local database and processed for local visualization and printed measurements reports for network operator. the information on the status of the intelligent gm probes are also provided, enabling the verification of measured results at the local control node. the central control node represents the pc-based highest monitoring network layer connected to the local control node using already existing lan infrastructure. the central control node hosts the central database, provides full insight into instantaneous gamma radiation levels at all measuring sites, provides archives on daily bases for all monitored locations and printed reports on measurements for all measuring sites at any time of gamma radiation measurement. (author)

  11. Organ Size Control Is Dominant over Rb Family Inactivation to Restrict Proliferation In Vivo

    Directory of Open Access Journals (Sweden)

    Ursula Ehmer

    2014-07-01

    Full Text Available In mammals, a cell’s decision to divide is thought to be under the control of the Rb/E2F pathway. We previously found that inactivation of the Rb family of cell cycle inhibitors (Rb, p107, and p130 in quiescent liver progenitors leads to uncontrolled division and cancer initiation. Here, we show that, in contrast, deletion of the entire Rb gene family in mature hepatocytes is not sufficient for their long-term proliferation. The cell cycle block in Rb family mutant hepatocytes is independent of the Arf/p53/p21 checkpoint but can be abrogated upon decreasing liver size. At the molecular level, we identify YAP, a transcriptional regulator involved in organ size control, as a factor required for the sustained expression of cell cycle genes in hepatocytes. These experiments identify a higher level of regulation of the cell cycle in vivo in which signals regulating organ size are dominant regulators of the core cell cycle machinery.

  12. Rb-intercalated C60 compounds studied by photoemission spectroscopies

    International Nuclear Information System (INIS)

    Brambilla, A.; Giovanelli, L.; Vilmercati, P.; Cattoni, A.; Biagioni, P.; Goldoni, A.; Finazzi, M.; Duo, L.

    2005-01-01

    We report on a combined photoemission and inverse photoemission spectroscopy analysis on Rb x C 60 compounds with different stoichiometries (0-bar x-bar 6). Apart from shifts and broadening of the spectral features associated to the different phase formed, we observe in the RbC 60 phase the presence of the highest occupied molecular orbital (HOMO) shoulder and of its symmetric (with respect to the Fermi level) empty state. According to calculations, the metallicity of this phase and the presence of these electronic states may be taken as a fingerprint of the interplay between electron-electron and electron-phonon interactions in determining the electronic behavior of alkali metal fullerides

  13. Experimental Model to Study the Role of Retinoblastoma Gene Product (pRb) for Determination of Adipocyte Differentiation.

    Science.gov (United States)

    Popov, B V; Shilo, P S; Zhidkova, O V; Zaichik, A M; Petrov, N S

    2015-06-01

    Using stable constitutive expression of retinoblastoma gene product (pRb) in polypotent mesenchymal 10T1/2 cells we obtained stable cell lines hyperexpressing functionally active or inactive mutant pRb. The cells producing active exogenous pRb demonstrated high sensitivity to adipocyte differentiation inductors, whereas production of inactive form of the exogenous protein suppressed adipocyte differentiation. The obtained lines can serve as the experimental model for studying the role of pRb in determination of adipocyte differentiation.

  14. A Measurement of $R_b$ using a Lifetime-Mass Tag

    CERN Document Server

    Barate, R; Décamp, D; Ghez, P; Goy, C; Lees, J P; Lucotte, A; Minard, M N; Nief, J Y; Pietrzyk, B; Casado, M P; Chmeissani, M; Comas, P; Crespo, J M; Delfino, M C; Fernández, E; Fernández-Bosman, M; Garrido, L; Juste, A; Martínez, M; Miquel, R; Mir, L M; Orteu, S; Padilla, C; Park, I C; Pascual, A; Perlas, J A; Riu, I; Sánchez, F; Teubert, F; Colaleo, A; Creanza, D; De Palma, M; Gelao, G; Iaselli, Giuseppe; Maggi, G; Maggi, M; Marinelli, N; Nuzzo, S; Ranieri, A; Raso, G; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Tricomi, A; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Abbaneo, D; Alemany, R; Becker, U; Bazarko, A O; Bright-Thomas, P G; Cattaneo, M; Cerutti, F; Drevermann, H; Forty, Roger W; Frank, M; Hagelberg, R; Harvey, J; Janot, P; Jost, B; Kneringer, E; Knobloch, J; Lehraus, Ivan; Lutters, G; Mato, P; Minten, Adolf G; Moneta, L; Pacheco, A; Pusztaszeri, J F; Ranjard, F; Rensing, P E; Rizzo, G; Rolandi, Luigi; Schlatter, W D; Schmitt, M; Schneider, O; Tejessy, W; Tomalin, I R; Wachsmuth, H W; Wagner, A; Ajaltouni, Ziad J; Barrès, A; Boyer, C; Falvard, A; Ferdi, C; Gay, P; Guicheney, C; Henrard, P; Jousset, J; Michel, B; Monteil, S; Montret, J C; Pallin, D; Perret, P; Podlyski, F; Proriol, J; Rosnet, P; Rossignol, J M; Fearnley, Tom; Hansen, J B; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Rensch, B; Wäänänen, A; Daskalakis, G; Kyriakis, A; Markou, C; Simopoulou, Errietta; Siotis, I; Vayaki, Anna; Blondel, A; Bonneaud, G R; Brient, J C; Bourdon, P; Rougé, A; Rumpf, M; Valassi, Andrea; Verderi, M; Videau, H L; Candlin, D J; Parsons, M I; Focardi, E; Parrini, G; Zachariadou, K; Corden, M; Georgiopoulos, C H; Jaffe, D E; Antonelli, A; Bencivenni, G; Bologna, G; Bossi, F; Campana, P; Capon, G; Casper, David William; Chiarella, V; Felici, G; Laurelli, P; Mannocchi, G; Murtas, F; Murtas, G P; Passalacqua, L; Pepé-Altarelli, M; Curtis, L; Dorris, S J; Halley, A W; Knowles, I G; Lynch, J G; O'Shea, V; Raine, C; Scarr, J M; Smith, K; Teixeira-Dias, P; Thompson, A S; Thomson, E; Thomson, F; Turnbull, R M; Geweniger, C; Graefe, G; Hanke, P; Hansper, G; Hepp, V; Kluge, E E; Putzer, A; Schmidt, M; Sommer, J; Tittel, K; Werner, S; Wunsch, M; Beuselinck, R; Binnie, David M; Cameron, W; Dornan, Peter J; Girone, M; Goodsir, S M; Martin, E B; Moutoussi, A; Nash, J; Sedgbeer, J K; Stacey, A M; Williams, M D; Dissertori, G; Ghete, V M; Girtler, P; Kuhn, D; Rudolph, G; Betteridge, A P; Bowdery, C K; Colrain, P; Crawford, G; Finch, A J; Foster, F; Hughes, G; Sloan, Terence; Williams, M I; Galla, A; Giehl, I; Greene, A M; Hoffmann, C; Jakobs, K; Kleinknecht, K; Quast, G; Renk, B; Rohne, E; Sander, H G; Van Gemmeren, P; Zeitnitz, C; Aubert, Jean-Jacques; Benchouk, C; Bonissent, A; Bujosa, G; Calvet, D; Carr, J; Coyle, P; Diaconu, C A; Etienne, F; Konstantinidis, N P; Leroy, O; Motsch, F; Payre, P; Rousseau, D; Talby, M; Sadouki, A; Thulasidas, M; Trabelsi, K; Aleppo, M; Ragusa, F; Berlich, R; Blum, Walter; Brown, D; Büscher, V; Dietl, H; Dydak, Friedrich; Ganis, G; Gotzhein, C; Kroha, H; Lütjens, G; Lutz, Gerhard; Männer, W; Moser, H G; Richter, R H; Rosado-Schlosser, A; Schael, S; Settles, Ronald; Seywerd, H C J; Saint-Denis, R; Stenzel, H; Wiedenmann, W; Wolf, G; Boucrot, J; Callot, O; Chen, S; Choi, Y; Cordier, A; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Höcker, A; Jacholkowska, A; Jacquet, M; Kim, D W; Le Diberder, F R; Lefrançois, J; Lutz, A M; Nikolic, I A; Schune, M H; Simion, S; Tournefier, E; Veillet, J J; Videau, I; Zerwas, D; Azzurri, P; Bagliesi, G; Batignani, G; Bettarini, S; Bozzi, C; Calderini, G; Carpinelli, M; Ciocci, M A; Ciulli, V; Dell'Orso, R; Fantechi, R; Ferrante, I; Foà, L; Forti, F; Giassi, A; Giorgi, M A; Gregorio, A; Ligabue, F; Lusiani, A; Marrocchesi, P S; Messineo, A; Palla, Fabrizio; Sanguinetti, G; Sciabà, A; Spagnolo, P; Steinberger, Jack; Tenchini, Roberto; Tonelli, G; Vannini, C; Venturi, A; Verdini, P G; Blair, G A; Bryant, L M; Chambers, J T; Gao, Y; Green, M G; Medcalf, T; Perrodo, P; Strong, J A; Von Wimmersperg-Töller, J H; Botterill, David R; Clifft, R W; Edgecock, T R; Haywood, S; Maley, P; Norton, P R; Thompson, J C; Wright, A E; Bloch-Devaux, B; Colas, P; Emery, S; Kozanecki, Witold; Lançon, E; Lemaire, M C; Locci, E; Pérez, P; Rander, J; Renardy, J F; Roussarie, A; Schuller, J P; Schwindling, J; Trabelsi, A; Vallage, B; Black, S N; Dann, J H; Johnson, R P; Kim, H Y; Litke, A M; McNeil, M A; Taylor, G; Booth, C N; Boswell, R; Brew, C A J; Cartwright, S L; Combley, F; Kelly, M S; Lehto, M H; Newton, W M; Reeve, J; Thompson, L F; Böhrer, A; Brandt, S; Cowan, G D; Grupen, Claus; Saraiva, P; Smolik, L; Stephan, F; Apollonio, M; Bosisio, L; Della Marina, R; Giannini, G; Gobbo, B; Musolino, G; Rothberg, J E; Wasserbaech, S R; Armstrong, S R; Charles, E; Elmer, P; Ferguson, D P S; Gao, Y S; González, S; Greening, T C; Hayes, O J; Hu, H; Jin, S; McNamara, P A; Nachtman, J M; Nielsen, J; Orejudos, W; Pan, Y B; Saadi, Y; Scott, I J; Walsh, J; Wu Sau Lan; Wu, X; Yamartino, J M; Zobernig, G

    1997-01-01

    ALEPH's published measurement of $R_b$ using a lifetime tag, is updated using the full LEP~1 data sample. Considerable effort has been devoted to understanding systematic effects. Charm background is better controlled by combining the lifetime tag with a tag based on the b/c hadron mass difference. Furthermore, the algorithm used to reconstruct the event primary vertex is designed so as to reduce correlations between the two hemispheres of an event. The value of $R_b$ is measured to be $0.2167\\pm 0.0011{\\mathrm (stat)}\\pm 0.0013{\\mathrm (syst)}$.

  15. RB Research nuclear reactor, Annual report for 1996, I-IV

    International Nuclear Information System (INIS)

    Stefanovic, D.; Milosevic, M.; Pesic, M.; Marinkovic, P.; Ilic, R.; Dasic, N.; Milovanovic, S.; Ljubenov, V.; Petronijevic, M.; Jevremovic, M.

    1996-12-01

    Report on RB reactor operation during 1996 contains 3 parts. Part one contains a brief description of reactor operation and reactor components, relevant dosimetry data and radiation protection issues, personnel and financial data. Part two is devoted to maintenance of the reactor components, namely, fuel, heavy water, reactor vessel, heavy water circulation system, absorption rods and heavy water level-meters, maintenance of electronic, mechanical, electrical and auxiliary equipment. Part three contains data concerned with reactor operation and utilization with a list of publications resulting from experiments done at the RB reactor

  16. RB Research nuclear reactor, Annual report for 1995, I-IV

    International Nuclear Information System (INIS)

    Stefanovic, D.; Milosevic, M.; Pesic, M.; Marinkovic, P.; Ilic, R.; Dasic, N.; Milovanovic, S.; Ljubenov, V.; Petronijevic, M.; Jevremovic, M.

    1995-12-01

    Report on RB reactor operation during 1995 contains 3 parts. Part one contains a brief description of reactor operation and reactor components, relevant dosimetry data and radiation protection issues, personnel and financial data. Part two is devoted to maintenance of the reactor components, namely, fuel, heavy water, reactor vessel, heavy water circulation system, absorption rods and heavy water level-meters, maintenance of electronic, mechanical, electrical and auxiliary equipment. Part three contains data concerned with reactor operation and utilization with a comprehensive list of publications resulting from experiments done at the RB reactor

  17. Synthesis, crystal structure, and properties of Na{sub 2}RbAuO{sub 2}; Synthese, Kristallstruktur und Eigenschaften von Na{sub 2}RbAuO{sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Mudring, A.V.; Jansen, M. [Max-Planck-Inst. fuer Festkoerperforschung, Stuttgart (Germany)

    2001-02-01

    Single phase samples of Na{sub 2}RbAuO{sub 2} were prepared by reacting RbAu with Na{sub 2}O{sub 2} in an equimolar ratio in sealed silver cylinders (placed under argon in glas tubes) at 400 C for two weeks. The colourless single crystals of needle shaped habitus decompose immediately when exposed to air. Na{sub 2}RbAuO{sub 2} (Pearsoncode oP12, Pnnm, a = 992.76(6), b = 559.03(3), c = 408.64(3) pm, Z = 2, 414 reflections with I{sub o} > 2{sigma}(I), R{sub 1} = 0.0363, wR{sub 2} = 0.1057) crystallizes isotypic with Na{sub 2}KAuO{sub 2}. Besides linear [O-Au-O] units, which are characteristic for oxoaurate(I), the structure reveals uncommon low coordination numbers for the alkali metal cations. (orig.)

  18. Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells.

    Science.gov (United States)

    Miles, Wayne O; Korenjak, Michael; Griffiths, Lyra M; Dyer, Michael A; Provero, Paolo; Dyson, Nicholas J

    2014-10-01

    Inactivation of the retinoblastoma tumor suppressor (pRb) is a common oncogenic event that alters the expression of genes important for cell cycle progression, senescence, and apoptosis. However, in many contexts, the properties of pRb-deficient cells are similar to wild-type cells suggesting there may be processes that counterbalance the transcriptional changes associated with pRb inactivation. Therefore, we have looked for sets of evolutionary conserved, functionally related genes that are direct targets of pRb/E2F proteins. We show that the expression of NANOS, a key facilitator of the Pumilio (PUM) post-transcriptional repressor complex, is directly repressed by pRb/E2F in flies and humans. In both species, NANOS expression increases following inactivation of pRb/RBF1 and becomes important for tissue homeostasis. By analyzing datasets from normal retinal tissue and pRb-null retinoblastomas, we find a strong enrichment for putative PUM substrates among genes de-regulated in tumors. These include pro-apoptotic genes that are transcriptionally down-regulated upon pRb loss, and we characterize two such candidates, MAP2K3 and MAP3K1, as direct PUM substrates. Our data suggest that NANOS increases in importance in pRb-deficient cells and helps to maintain homeostasis by repressing the translation of transcripts containing PUM Regulatory Elements (PRE). © 2014 The Authors.

  19. Ginsenosides Rb1 and Rg1 Stimulate Melanogenesis in Human Epidermal Melanocytes via PKA/CREB/MITF Signaling

    Directory of Open Access Journals (Sweden)

    Mao Lin

    2014-01-01

    Full Text Available Reduced or defective melanin skin pigmentation may cause many hypopigmentation disorders and increase the risk of damage to the skin triggered by UV irradiation. Ginsenosides Rb1 and Rg1 have many molecular targets including the cAMP-response element-binding protein (CREB, which is involved in melanogenesis. This study aimed to investigate the effects of ginsenosides Rb1 and Rg1 on melanogenesis in human melanocytes and their related mechanisms. The effects of Rb1 and Rg1 on cell viability, tyrosinase activity, cellular melanin content and protein levels of tyrosinase, microphthalmia-associated transcription factor (MITF, and activation of CREB in melanocytes were assessed. Results showed that Rb1 or Rg1 significantly increased cellular melanin content and tyrosinase activity in a dose-dependent manner. By contrast, the cell viability of melanocytes remained unchanged. After exposure to Rb1 or Rg1, the protein levels of tyrosinase, MITF, and phosphorylated CREB were significantly increased. Furthermore, pretreatment with the selective PKA inhibitor H-89 significantly blocked the Rb1- or Rg1-induced increase of melanin content. These findings indicated that Rb1 and Rg1 increased melanogenesis and tyrosinase activity in human melanocytes, which was associated with activation of PKA/CREB/MITF signaling. The effects and mechanisms of Rb1 or Rg1 on skin pigmentation deserve further study.

  20. RNAi mediated acute depletion of Retinoblastoma protein (pRb promotes aneuploidy in human primary cells via micronuclei formation

    Directory of Open Access Journals (Sweden)

    Iovino Flora

    2009-11-01

    Full Text Available Abstract Background Changes in chromosome number or structure as well as supernumerary centrosomes and multipolar mitoses are commonly observed in human tumors. Thus, centrosome amplification and mitotic checkpoint dysfunctions are believed possible causes of chromosomal instability. The Retinoblastoma tumor suppressor (RB participates in the regulation of synchrony between DNA synthesis and centrosome duplication and it is involved in transcription regulation of some mitotic genes. Primary human fibroblasts were transfected transiently with short interfering RNA (siRNA specific for human pRb to investigate the effects of pRb acute loss on chromosomal stability. Results Acutely pRb-depleted fibroblasts showed altered expression of genes necessary for cell cycle progression, centrosome homeostasis, kinetochore and mitotic checkpoint proteins. Despite altered expression of genes involved in the Spindle Assembly Checkpoint (SAC the checkpoint seemed to function properly in pRb-depleted fibroblasts. In particular AURORA-A and PLK1 overexpression suggested that these two genes might have a role in the observed genomic instability. However, when they were post-transcriptionally silenced in pRb-depleted fibroblasts we did not observe reduction in the number of aneuploid cells. This finding suggests that overexpression of these two genes did not contribute to genomic instability triggered by RB acute loss although it affected cell proliferation. Acutely pRb-depleted human fibroblasts showed the presence of micronuclei containing whole chromosomes besides the presence of supernumerary centrosomes and aneuploidy. Conclusion Here we show for the first time that RB acute loss triggers centrosome amplification and aneuploidy in human primary fibroblasts. Altogether, our results suggest that pRb-depleted primary human fibroblasts possess an intact spindle checkpoint and that micronuclei, likely caused by mis-attached kinetochores that in turn trigger

  1. Inhibition of white light of 86Rb+ absorption in the root apex of corn

    International Nuclear Information System (INIS)

    McKendree, W.L.; Smith, R.C.

    1990-01-01

    Measurements of cell lengths made at 0.5 millimeter intervals in median longitudinal sections of the primary roots of corn (Zea mays) were used to construct a growth curve. The region 1.5 to 4.0 millimeters from the apex contained the largest number of elongating cells. Absorption of 86 Rb + was measured using intact, dark-grown corn seedlings. Following uptake and exchange, the terminal 8.0 millimeters of each root was cut into four 2.0 millimeter segments. Maximum 86 Rb + uptake occurred in the region from 0.0 to 4.0 millimeter from the root tip. Washing the intact primary root in fresh 2.0 millimolar CaSO 4 for 2 hours prior to uptake augmented the rate of 86 Rb + uptake in all regions. Illumination with white light during washing caused a reduction of 86 Rb + uptake as compared with controls washing in darkness, and the region of greatest light response was the region of elongation. Removal of the coleoptile prior to washing did not prevent the light inhibition of subsequent 86 Rb + uptake. Removal of the root cap prior to washing in light partially reversed the light-induced inhibition of the washing response

  2. Rb/Sr dating of rock samples from Antarctica

    International Nuclear Information System (INIS)

    Ahmed, A.; Awan, M.A.; Mehjabeen, A.; Jabeen, N.; Majid, C.A.

    1996-01-01

    Soon after the discovery of radioactivity in 1896 by Becquerel, the phenomenon was applied to geochronology. From 1902 onwards, rapid advances were made in this field of science. Using radiometric techniques of Rb/Sr the whole rock granitic pegmatite samples from two localities in the North Eastern Antarctica have been dated. The rock samples have yielded Rb/Sr ages around 200 nd 173 million year. The ages around 200 million year have been correlated to the orogenic/epeirogenic activities associated with the breaking up of the Pangaea which led to the dispersion of the continents to form Gondwanaland and Laurasia which subsequently gave rise to the present day configuration of the globe. The younger age of 173 million year corresponds to Jurassic dole rites from Western queens Maud Land and other areas of Antarctica. (author)

  3. Raman spectra of the solid-solution between Rb sub 2 La sub 2 Ti sub 3 O sub 1 sub 0 and RbCa sub 2 Nb sub 3 O sub 1 sub 0

    CERN Document Server

    Kim, H J; Yun, H S

    2001-01-01

    A site preference of niobium atom in Rb sub 2 sub - sub x La sub 2 Ti sub 3 sub - sub x Nb sub x O sub 1 sub 0 (0.0<=x<=1.0) and RbLa sub 2 sub - sub x Ca sub x Ti sub 2 sub - sub x Nb sub 1 sub + sub x O sub 1 sub 0 (0.0<=x<= 2.0), which are the solid-solutions between Rb sub 2 La sub 2 Ti sub 3 O sub 1 sub 0 are RbCa sub 2 Nb sub 3 O sub 1 sub 0 , has been investigated by Raman spectroscopy. The Raman spectra of Rb sub 2 sub - sub x La sub 2 Ti sub 3 sub - sub x Nb sub x O sub 1 sub 0 (0.0<=x<=1.0) gave an evidence that niobium atoms substituted for titanium atoms preferably occupy the highly distorted outer octahedral sites rather than the central ones in triple-octahedral perovskite layers. In contrast, the Raman spectra of RbLa sub 2 sub - sub x Ca sub x Ti sub 2 sub - sub x Nb sub 1 sub + sub x O sub 1 sub 0 (0.0<=x<= 2.0) showed no clear information for the cationic arrangement in perovskite slabs. This difference indicated that a site preference of niobium atoms is observed onl...

  4. Operation and maintenance of the RB reactor, Annual report for 1977

    International Nuclear Information System (INIS)

    Sotic, O.; Vranic, S.

    1977-01-01

    The annual report for 1977 includes the following: utilization of the RB reactor; new regulations and instructions for reactor operation; improvement of experimental possibilities of the RB reactor; state of the reactor equipment; dosimetry and radiation protection; reactor staff. Five annexes are concerned with: testing the properties of preamplifiers for linear and logarithmic experimental channels; properties of the neutron converter; maintenance of the reactor equipment; purchase of new equipment; and the program for training reactor operators

  5. Rb-Sr mantle isochrons from oceanic regions

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, C; Hart, S R; Hofmann, A; James, D E [Carnegie Institution of Washington, D.C. (USA). Dept. of Terrestrial Magnetism

    1976-09-01

    Existing data for /sup 87/Sr//sup 86/Sr and Rb/Sr ratios of basalts from oceanic islands and mid-ocean spreading ridges show significant positive correlations on a Rb-Sr isochron diagram (when data are averaged by island group). Furthermore, tholeiites and alkali basalts occupy distinct non-overlapping fields on this plot. The tholeiite correlation is interpreted as a mantle isochron, and the agreement of this age (1.6+-0.2 b.y.) with that reported for Pb-Pb isochrons from oceanic basalts lends strong support to the use of such isochrons for tracing mantle evolution. Oceanic basalts are apparently sampling a mantle in which chemical heterogeneities have persisted for at least 1.5-2.0 b.y. The data support a kinematic model for the mantle in which a relatively uniform and non-radiogenic asthenosphere is penetrated by, and mixed with, blobs or plumes derived from an isolated (1.5-2 b.y.) and chemically heterogeneous mesosphere.

  6. Total absorption γ -ray spectroscopy of the β -delayed neutron emitters Br87 , Br88 , and Rb94

    Energy Technology Data Exchange (ETDEWEB)

    Valencia, E.; Tain, J. L.; Algora, A.; Agramunt, J.; Estevez, E.; Jordan, M. D.; Rubio, B.; Rice, S.; Regan, P.; Gelletly, W.; Podolyák, Z.; Bowry, M.; Mason, P.; Farrelly, G. F.; Zakari-Issoufou, A.; Fallot, M.; Porta, A.; Bui, V. M.; Rissanen, J.; Eronen, T.; Moore, I.; Penttilä, H.; Äystö, J.; Elomaa, V. -V.; Hakala, J.; Jokinen, A.; Kolhinen, V. S.; Reponen, M.; Sonnenschein, V.; Cano-Ott, D.; Garcia, A. R.; Martínez, T.; Mendoza, E.; Caballero-Folch, R.; Gomez-Hornillos, B.; Gorlichev, V.; Kondev, F. G.; Sonzogni, A. A.; Batist, L.

    2017-02-01

    We investigate the decay of Br-87,Br-88 and Rb-94 using total absorption gamma-ray spectroscopy. These important fission products are beta-delayed neutron emitters. Our data show considerable beta gamma intensity, so far unobserved in high-resolution gamma-ray spectroscopy, from states at high excitation energy. We also find significant differences with the beta intensity that can be deduced from existing measurements of the beta spectrum. We evaluate the impact of the present data on reactor decay heat using summation calculations. Although the effect is relatively small it helps to reduce the discrepancy between calculations and integral measurements of the photon component for U-235 fission at cooling times in the range 1-100 s. We also use summation calculations to evaluate the impact of present data on reactor antineutrino spectra. We find a significant effect at antineutrino energies in the range of 5 to 9 MeV. In addition, we observe an unexpected strong probability for. emission from neutron unbound states populated in the daughter nucleus. The. branching is compared to Hauser-Feshbach calculations, which allow one to explain the large value for bromine isotopes as due to nuclear structure. However the branching for Rb-94, although much smaller, hints of the need to increase the radiative width gamma by one order of magnitude. This increase in gamma would lead to a similar increase in the calculated (n, gamma) cross section for this very neutron-rich nucleus with a potential impact on r process abundance calculations.

  7. Brucella abortus RB51 in milk of vaccinated adult cattle.

    Science.gov (United States)

    Miranda, Karina Leite; Poester, Fernando Padilla; Dorneles, Elaine Maria Seles; Resende, Thiago Magalhães; Vaz, Adil Knackfuss; Ferraz, Sandra Maria; Lage, Andrey Pereira

    2016-08-01

    The aim of this study was to evaluate the shedding of Brucella abortus in the milk of cows vaccinated with a full dose of RB51 during lactation. Eighteen cows, nine previously vaccinated with S19 as calves and nine non-vaccinated, were immunized subcutaneously with 1.3×10(10)CFU of B. abortus RB51, 30-60days after parturition. Milk samples from all animals were collected daily until day 7, and at weekly interval for the next 9 weeks after vaccination. To evaluate the shedding of B. abortus, milk samples were submitted for culture and PCR. No B. abortus was isolated from any sample tested. Only one sample, collected on first day after vaccination from a cow previously vaccinated, was faintly positive in the PCR. In conclusion, the public health hazard associated with milk consumption from cows vaccinated with RB51 in post-partum is very low, despite vaccination with the full dose and regardless of previous S19 vaccination. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase

    Energy Technology Data Exchange (ETDEWEB)

    Terashima, Minoru; Ishimura, Akihiko; Yoshida, Masakazu [Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Ishikawa (Japan); Suzuki, Yutaka; Sugano, Sumio [Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8561, Chiba (Japan); Suzuki, Takeshi, E-mail: suzuki-t@staff.kanazawa-u.ac.jp [Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Ishikawa (Japan)

    2010-08-20

    Research highlights: {yields} Utx increases expression of Rb and Rbl2 genes through its demethylase activity. {yields} Utx changes histone H3 methylation on the Rb and Rbl2 promoters. {yields} Utx induces decreased cell proliferation of mammalian primary cells. -- Abstract: Utx is a candidate tumor suppressor gene that encodes histone H3 lysine 27 (H3K27) demethylase. In this study, we found that ectopic expression of Utx enhanced the expression of retinoblastoma tumor suppressor gene Rb and its related gene Rbl2. This activation was dependent on the demethylase activity of Utx, and was suggested to contribute to the decreased cell proliferation induced by Utx. A chromatin immunoprecipitation assay showed that over-expressed Utx was associated with the promoter regions of Rb and Rbl2 resulting in the removal of repressive H3K27 tri-methylation and the increase in active H3K4 tri-methylation. Furthermore, siRNA-mediated knockdown of Utx revealed the recruitment of endogenous Utx protein on the promoters of Rb and Rbl2 genes. These results indicate that Rb and Rbl2 are downstream target genes of Utx and may play important roles in Utx-mediated cell growth control.

  9. Molecular screening of compounds to the predicted Protein-Protein Interaction site of Rb1-E7 with p53- E6 in HPV

    Science.gov (United States)

    Shaikh, Faraz; Sanehi, Parvish; Rawal, Rakesh

    2012-01-01

    Cervical cancer is malignant neoplasm of the cervix uteri or cervical area. Human Papillomaviruses (HPVs) which are heterogeneous groups of small double stranded DNA viruses are considered as the primary cause of cervical cancer, involved in 90% of all Cervical Cancers. Two early HPV genes, E6 and E7, are known to play crucial role in tumor formation. E6 binds with p53 and prevents its translocation and thereby inhibit the ability of p53 to activate or repress target genes. E7 binds to hypophosphorylated Rb and thereby induces cells to enter into premature S-phase by disrupting Rb-E2F complexes. The strategy of the research work was to target the site of interaction of Rb1 -E7 & p53-E6. A total of 88 compounds were selected for molecular screening, based on comprehensive literature survey for natural compounds with anti-cancer activity. Molecular docking analysis was carried out with Molegro Virtual Docker, to screen the 88 chosen compounds and rank them according to their binding affinity towards the site of interaction of the viral oncoproteins and human tumor suppressor proteins. The docking result revealed that Nicandrenone a member of Withanolides family of chemical compounds as the most likely molecule that can be used as a candidate drug against HPV induced cervical cancer. Abbreviations HPV - Human Papiloma Virus, HTSP - Human Tumor Suppressor Proteins, VOP - Viral oncoproteins. PMID:22829740

  10. Experimental techniques applied at the RB reactor

    International Nuclear Information System (INIS)

    Markovic, H.; Takac, S.; Sotic, O.; Dimitrijevic, Z.

    1979-12-01

    This paper contains a brief description of research and operations at the RB reactor which are concerned with experiments and results of measuring typical reactor parameters, neutron characteristics as well as parameters related to reactor operation and utilization. Annex contains a list of relevant original papers and publications [sr

  11. Role of diacylglycerol in adrenergic-stimulated sup 86 Rb uptake by proximal tubules

    Energy Technology Data Exchange (ETDEWEB)

    Baines, A.D.; Drangova, R.; Ho, P. (Univ. of Toronto, Ontario (Canada))

    1990-05-01

    We used rat proximal tubule fragments purified by Percoll centrifugation to examine the role of diacylglycerol (DAG) in noradrenergic-stimulated Na+ reabsorption. Tubular DAG concentration and ouabain-inhibitable 86Rb uptake increased within 30 s after adding norepinephrine (NE) and remained elevated for at least 5 min. NE (1 microM) increased DAG content 17% and ouabain-inhibitable 86Rb uptake 23%. Cirazoline-stimulated 86Rb uptake was not inhibited by BaCl, quinidine, or bumetanide (1-10 microM) or by the omission of HCO3- or Cl- from the medium, but it was completely inhibited by ouabain and furosemide. Oleoyl-acetyl glycerol, L-alpha-1,2-dioctanoylglycerol, and L-alpha-1,2-dioleoylglycerol (DOG) increased total 86Rb uptake 8-11%. 12-O-tetradecanoylphorbol-13-acetate (TPA) (5 nM) increased uptake by only 4%. Staurosporine at 5 nM inhibited DOG stimulation completely, whereas 50 nM staurosporine was required to inhibit NE stimulation completely. Sphingosine inhibited DOG stimulation by 66% but did not inhibit NE stimulation. Amiloride (1 mM) completely blocked DOG stimulation. Monensin increased 86Rb uptake 31% and completely blocked the DOG effect but reduced the NE effect by only 26% (P = 0.08). In tubules from salt-loaded rats, NE did not increase DAG concentration, but NE-stimulated 86Rb uptake was reduced by only 23% (P = 0.15). Thus DAG released by NE may stimulate Na+ entry through Na(+)-H+ exchange. NE predominantly stimulates Na(+)-K(+)-adenosinetriphosphatase (ATPase) by activating a protein kinase that is insensitive to DAG and TPA and is inhibited by staurosporine but not by sphingosine. NE may also stimulate K+ efflux through a BaCl-insensitive K+ channel that is inhibited by millimolar furosemide.

  12. Preliminary design characteristics of the RB fast-thermal core 'HERBE'

    International Nuclear Information System (INIS)

    Pesic, M.; Marinkovic, P.

    1989-01-01

    The 'RB' is zero power heavy water critical assembly designed in 1958 in Yugoslavia. The reactor operated using natural metal uranium, 2% enriched metal uranium, and 80% enriched UO 2 fuel of Soviet origin. A study of design of fast neutron fields began in 1976 and three fast neutron fields were designed up to 1983: the external neutron converter, the experimental fuel channel and the internal neutron converter, as the first step to fast-thermal coupled system. The preliminary design characteristics of the HERBE - a new fast - thermal core at the RB reactor are shown in this paper. (author)

  13. The Rb-Sr geochronology of the Colossus kimberlite pipe, Zimbabwe

    International Nuclear Information System (INIS)

    Allsopp, H.L.

    1985-01-01

    The Colossus kimberlite is one of several such occurrences situated in central Zimbabwe. A relationship with alluvial diamond deposits in the same area has been suggested, and on this basis a pre-Permian age has been inferred. The general geology and petrography of the Colossus kimberlite pipe are described. Rb-Sr age measurements on somewhat weathered kimberlite micas are reported, and the best estimate for the age of the kimberlite is reported as 502+-47 Ma. A model Rb-Sr age of 2 630 Ma for the Formona granite, which forms the country rock to the kimberlite, is also reported

  14. Rayleigh scattering of Moessbauer radiation in superionic conductor RbAg4I5

    International Nuclear Information System (INIS)

    Ovanesyan, N.S.; Goffman, V.G.; Sokolov, V.B.; Tkachev, V.V.

    1984-01-01

    The dynamical properties of RbAg 4 I 5 has been investiaated by Rayleigh scattering of Moessbauer radiation (RSMR) with wave-length lambda = 0.86 A. The character of Ag + ion oscillatory motion and diffusion in RbAg 4 I 5 depending on temperature including the phase transitions region is studied. It is shown that in the superionic crystal RbAg 4 I 5 the diffusion process is strongly correlated, i.e. a great number of initial and final states at diffusion jumps coincides. The observed broadening can be less than the expected one by value orders. Diffusion correlation can strongly reduce the activation barrier and lead to anomalously high ionic conduction

  15. Determination of improved myocardial perfusion after aortocoronary bypass surgery by exercise 81Rb scintigraphy

    International Nuclear Information System (INIS)

    Lurie, A.J.; Salel, A.F.; Berman, D.S.; DeNardo, G.L.; Hurley, E.J.; Mason, D.T.

    1976-01-01

    Practical and noninvasive means are needed for evaluating efficacy of coronary bypass surgery (CBS) in improving blood flow (CBF) to ischemic myocardium in coronary patients. Revascularization was assessed in 15 patients by pre- and post-CBS rest and exercise rubidium-81 myocardial images with a scintillation camera equipped with pinhole collimator and high-energy shield. Ischemic areas were detected by decreased 81 Rb activity after exercise compared to rest. Before CBS all patients had exercise angina (EA), positive treadmill ECG (TECG), and abnormal exercise 81 Rb scans. After CBS all 15 patients had increased physical activity before angina or completion of treadmill exercise with increased heart rate-blood pressure product (HRBP) (+63 +/- 3.2 x 10(2) bpm - mm Hg) in 14 of 15 patients indicating increased CBF; four had positive TECG, and five had EA. The increased HRBP in 14 patients was associated with improved post-CBS exercise 81 Rb scans: six had normal patterns while nine were improved with less ischemic patterns. Further, lack of angina and increased exercise tolerance correlated closely with increased 81 Rb myocardial perfusion. Thus pre- and postoperative rest and exercise 81 Rb scintigraphy gives an accurate, noninvasive, objective approach for evaluation of CBF following CBS and demonstrates the usefulness of this revascularization procedure in coronary patients

  16. Leiurus quinquestriatus venom inhibits BRL 34915-induced 86Rb+ efflux from the rat portal vein

    International Nuclear Information System (INIS)

    Quast, U.; Cook, N.S.

    1988-01-01

    The effect of the crude venom of the Israeli scorpion Leiurus quinquestriatus hebraeus on the 86 Rb + efflux stimulated by the K + channel opener BRL 34915 in the rat portal vein was examined. Applied alone, the venom greatly increased the spontaneous mechanical activity of and the concomitant 86 Rb + efflux from the vessel. When the excitability of the vein was suppressed by the dihydropyridine calcium antagonist, PN 200-110, the 86 Rb + efflux stimulated by BRL 34915 could be shown to be inhibited by the venom. From the concentration dependence of this inhibition an IC 50 value of 0.17 +/- 0.01 mg/ml was estimated. This venom is thus the most potent blocker of BRL 34915-evoked 86 Rb + efflux reported so far. 17 references, 2 figures

  17. A pathological study on overexpression of c-fos and Rb proteins in human radiation skin ulcer

    International Nuclear Information System (INIS)

    Du Yuejiao; Wang Dewen; Gao Yabing

    1996-01-01

    We performed an immunohistochemical study on human radiation skin ulcer by using antibodies against c-fos and Rb proteins and antigen-repairing method with a microwave oven. We found that the positive rates of overexpression of c-fos and Rb proteins were 84.0% and 100%, respectively. The overexpression of c-fos protein was mainly observed in cell nuclei of squamous epithelial cells, fibroblasts, endothelial cells, and leiomyocytes in media and fibrocytes in adventitia of arterioles. The location of the Rb protein overexpression was mostly similar to that of c-fos protein. The overexpression of c-fos and Rb proteins may be related to cancer transformation and poor healing of radiation-induced skin ulcers

  18. Operation and maintenance of the RB reactor, Annual report for 1978

    International Nuclear Information System (INIS)

    Sotic, O.; Vranic, S.

    1978-01-01

    The annual report for 1978 includes the following: utilization of the RB reactor; producing the new safety report; improvement of experimental possibilities of the RB reactor; state of the reactor equipment; dosimetry and radiation protection; reactor staff. Four annexes to this report are concerned with: operation of the reactor at higher power levels; performance of the instrumentation, radiation doses during operation; gamma radiation doses after reactor shutdown; properties of the neutron converter (optimization of the rector-converter coupling; maintenance of the reactor equipment; purchase of new equipment

  19. Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion

    Directory of Open Access Journals (Sweden)

    Xiaonan Qiu

    2017-03-01

    Full Text Available Elongation factor, RNA polymerase II, 2 (ELL2 is expressed and regulated by androgens in the prostate. ELL2 and ELL-associated factor 2 (EAF2 form a stable complex, and their orthologs in Caenorhabditis elegans appear to be functionally similar. In C. elegans, the EAF2 ortholog eaf-1 was reported to interact with the retinoblastoma (RB pathway to control development and fertility in worms. Because RB loss is frequent in prostate cancer, ELL2 interaction with RB might be important for prostate homeostasis. The present study explored physical and functional interaction of ELL2 with RB in prostate cancer. ELL2 expression in human prostate cancer specimens was detected using quantitative polymerase chain reaction coupled with laser capture microdissection. Co-immunoprecipitation coupled with deletion mutagenesis was used to determine ELL2 association with RB. Functional interaction between ELL2 and RB was tested using siRNA knockdown, BrdU incorporation, Transwell, and/or invasion assays in LNCaP, C4-2, and 22Rv1 prostate cancer cells. ELL2 expression was downregulated in high–Gleason score prostate cancer specimens. ELL2 could be bound and stabilized by RB, and this interaction was mediated through the N-terminus of ELL2 and the C-terminus of RB. Concurrent siRNA knockdown of ELL2 and RB enhanced cell proliferation, migration, and invasion as compared to knockdown of ELL2 or RB alone in prostate cancer cells. ELL2 and RB can interact physically and functionally to suppress prostate cancer progression.

  20. Investigation of the s-process branch-point nucleus {sup 86}Rb at HIγS

    Energy Technology Data Exchange (ETDEWEB)

    Erbacher, Philipp; Glorius, Jan; Reifarth, Rene; Sonnabend, Kerstin [Goethe Universitaet Frankfurt am Main (Germany); Isaak, Johann; Loeher, Bastian; Savran, Deniz [GSI Helmholzzentrum fuer Schwerionenforschung (Germany); Tornow, Werner [Duke University (United States)

    2016-07-01

    The branch-point nucleus {sup 86}Rb determines the isotopic abundance ratio {sup 86}Sr/{sup 87}Sr in s-process nucleosynthesis. Thus, stellar parameters such as temperature and neutron density and their evolution in time as simulated by modern s-process network calculations can be constrained by a comparison of the calculated isotopic ratio with the one observed in SiC meteoritic grains. To this end, the radiative neutron-capture cross section of the unstable isotope {sup 86}Rb has to be known with sufficient accuracy. Since the short half-life of {sup 86}Rb prohibits the direct measurement, the nuclear-physics input to a calculation of the cross section has to be measured. For this reason, the γ-ray strength function of {sup 87}Rb was measured using the γ{sup 3} setup at the High Intensity γ-ray Source facility at TUNL in Durham, USA. First experimental results are presented.

  1. Study of reactor parameters of on critical systems, Phase I: Safety report for RB zero power reactor

    International Nuclear Information System (INIS)

    Raisic, N.

    1962-09-01

    In addition to the safety analysis for the zero power RB reactor, this report contains a general description of the reactor, reactor components, auxiliary equipment and the reactor building. Reactor Rb has been reconstructed during 1961-1962 and supplied with new safety-control system as well as with a complete dosimetry instrumentation. Since RB reactor was constructed without shielding special attention is devoted to safety and protection of the staff performing experiments. Due to changed circumstances in the Institute ( start-up of the RA 7 MW power reactor) the role of the RB reactor was redefined

  2. Efficacy of dart or booster vaccination with strain RB51 in protecting bison against experimental Brucella abortus challenge

    Science.gov (United States)

    Vaccination is an effective tool for reducing the prevalence of brucellosis in natural hosts. In this study, we characterized the efficacy of the Brucella abortus strain RB51 (RB51) vaccine in bison when delivered by single intramuscular vaccination (Hand RB51), single pneumatic dart delivery (Dart ...

  3. Determination of blood circulation in oral formations using Rb86 distribution method and labelled micropearl method

    International Nuclear Information System (INIS)

    Fazekas, A.; Posch, E.; Harsing, L.

    1979-01-01

    The blood circulation of incisors, dental pulp and tongue was detemined using the measurement of 86 Rb distribution in rats. The results were compared with those obtained by a simultaneous micropearl method. It was found that 37 per cent of 86 Rb in dental tissues is localized in the hard propiodentium, with a high proportion diffusing from the periodontium. The 86 Rb fraction localized in the tongue represents its blood circulation. (author)

  4. Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression

    NARCIS (Netherlands)

    Nantasanti, Sathidpak; Toussaint, Mathilda J. M.; Youssef, Sameh A.; Tooten, Peter C. J.; de Bruin, Alain

    2016-01-01

    The tumor suppressors Retinoblastoma (Rb) and p53 are frequently inactivated in liver diseases, such as hepatocellular carcinomas (HCC) or infections with Hepatitis B or C viruses. Here, we discovered a novel role for Rb and p53 in xenobiotic metabolism, which represent a key function of the liver

  5. Pemanfaatan Mikrotik RB750 Untuk Jaringan Wifi Pada SMK Muhammadiyah Kudus

    Directory of Open Access Journals (Sweden)

    R Rhoedy Setiawan

    2013-06-01

    Full Text Available Abstrak Dengan kendala user yang terbatas dan software pencatatan user yang terdata yang relatif mahal, pendekatan yang dilakukan adalah pembuatan sebuah software yang ke depan bisa menekan biaya.Pengaksesan internet untuk kalangan SMK Muhammadiyah Kudus dibatasi penggunaannya untuk penghematan biaya pembelian bandwidht akses internet.Pengaturan hak akses internet di SMK Muhammadiyah Kudus sekarang ini menggunakan mikrotik RB 750. Diharapkan alat yang digunakan dapat mencapai pengguna yang lebih banyak, diantara alat pilihan lain yang digunakan dalam penelitian jaringan berbasis wifi. Keyword: software, microtic rb750, bandwidht

  6. Investigation of the magnetic structure of KFeCl3, KFeBr3, Rb2MnCl4, and Rb3Mn2Cl7 compounds with magnetic correlations in one and two dimensions

    International Nuclear Information System (INIS)

    Gurewitz, E.

    1976-12-01

    The crystallographic structure of KFeCl 3 and KFeBr 3 consists of (FeCl) - octahedra packed in isolated zigzagging chains. These compounds order antiferromagnetically at Tsub(N) approximately 16 deg K and Tsub(N) approximately 9.5 deg K, respectively. Below Tsub(N) the Fe 2+ magnetic moments within a chain are ferromagnetically coupled, parallel to the chain axis, while the chains are coupled antiferromagnetically. In the temperatures Tsub(N) 3 has magnetic correlations within the chains only, whereas the correlations between the chains are negligible. Moessbauer effect measurements at these temperatures show a distinct hyperfine magnetic splitting, characteristic of relaxation phenomena. Cs 2 MnCl 4 , Rb 2 MnCl 4 and Rb 3 Mn 2 Cl 7 belong to the Asub(n+1)Bsub(n)Xsub(3n+1) family of compounds, with the Dsub(4h)sup(17) space group. These compounds order antiferromagnetically at Tsub(N) approximately 55 deg K for Cs 2 MnCl 4 and Rb 2 MnCl 4 , and Tsub(N) approximately 64.5 deg K for Rb 3 Mn 2 Cl 7 . Below Tsub(N) each Mn 2+ moment is along the c-axis and is coupled antiferromagnetically to the moments of its nearest neighbours (nn). These compounds behave like a two-dimensional antiferromagnet at T >= Tsub(N). Neutron scans of the reciprocal space exhibit rods of reflections along c vectorsup(*). The negligible interactions between next nn sets of MnCl 2 layers, a distance c vector apart, yield both in Rb 2 MnCl 4 and in Rb 3 Mn 2 Cl 7 , two distinctive magnetic structures (polytypes) below Tsub(N). (author)

  7. P53 and Rb tumor suppressor gene alterations in gastric cancer Alterações dos genes supressores tumorais p53 e Rb no câncer gástrico

    Directory of Open Access Journals (Sweden)

    Rejane Mattar

    2004-01-01

    Full Text Available Inactivation of tumor suppressor genes has been frequently observed in gastric carcinogenesis. Our purpose was to study the involvement of p53, APC, DCC, and Rb genes in gastric carcinoma. METHOD: Loss of heterozygosity of the p53, APC, DCC and Rb genes was studied in 22 gastric cancer tissues using polymerase chain reaction; single-strand conformation polymorphism of the p53 gene exons 5-6 and exons 7-8 was studied using 35S-dATP, and p53 expression was detected using a histological immunoperoxidase method with an anti-p53 clone. RESULTS AND DISCUSSION: No loss of heterozygosity was observed in any of these tumor suppressor genes; homozygous deletion was detected in the Rb gene in 23% (3/13 of the cases of intestinal-type gastric carcinoma. Eighteen (81.8% cases showed band mobility shifts in exons 5-6 and/or 7-8 of the p53 gene. The presence of the p53 protein was positive in gastric cancer cells in 14 cases (63.6%. Normal gastric mucosa showed negative staining for p53; thus, the immunoreactivity was likely to represent mutant forms. The correlation of band mobility shift and the immunoreactivity to anti-p53 was not significant (P = .90. There was no correlation of gene alterations with the disease severity. CONCLUSIONS: The inactivation of Rb and p53 genes is involved in gastric carcinogenesis in our environment. Loss of the Rb gene observed only in the intestinal-type gastric cancer should be further evaluated in association with Helicobacter pylori infection. The p53 gene was affected in both intestinal and diffuse histological types of gastric cancer.A inativação de genes supressores tumorais tem sido freqüentemente observada na carcinogênese gástrica. O nosso objetivo foi estudar o envolvimento dos genes p53, APC, DCC e Rb no câncer gástrico. MÉTODO: Vinte e dois casos de câncer gástrico foram estudados por PCR-LOH (reação de polimerase em cadeia- perda de alelo heterozigoto dos genes p53, APC, DCC e Rb; e por PCR-SSCP (rea

  8. Formation times of RbHe exciplexes on the surface of superfluid versus normal fluid helium nanodroplets

    International Nuclear Information System (INIS)

    Droppelmann, G.; Buenermann, O.; Stienkemeier, F.; Schulz, C.P.

    2004-01-01

    Nanodroplets of either superfluid He 4 or normal fluid He 3 are doped with Rb atoms that are bound to the surface of the droplets. The formation of RbHe exciplexes upon 5P 3/2 excitation is monitored in real time by femtosecond pump-probe techniques. We find formation times of 8.5 and 11.6 ps for Rb He 4 and Rb He 3 , respectively. A comparison to calculations based on a tunneling model introduced for these systems by Reho et al. [J. Chem. Phys. 113, 9694 (2000)] shows that the proposed mechanism cannot account for our findings. Apparently, a different relaxation dynamics of the superfluid opposed to the normal fluid surface is responsible for the observed formation times

  9. Structural studies of precursor and partially oxidized conducting complexes. XIII. A neutron diffraction and x-ray diffuse scattering study of the dimerized platinum chain in rubidium tetracyanoplatinate chloride (2:1:0.3) trihydrate, Rb2[Pt(CN)4]Cl03.3.0H2O

    International Nuclear Information System (INIS)

    Williams, J.M.; Johnson, P.L.; Schultz, A.J.; Coffey, C.C.

    1978-01-01

    The crystal structure and molecular formula of the one-dimensional conductor Rb 2 [Pt(CN) 4 ]Cl 0 . 30 . 3.0H 2 O, RbCP(Cl), have been fully characterized using single-crystal neutron diffraction, x-ray diffuse scattering data, and thermogravimetric analysis. RbCP(Cl) is isostructural with KCP(Cl) and KCP(Br) except that only one halide site can be identified. From thermogravimetric analyses RbCP(Cl) is a 3.0 hydrate as is KCP(Br). RbCP(Cl) crystallizes in the tetragonal space group P4mm, with unit cell dimensions a = 10.142 (6) A, c = 5.801 (4) A, V/sub c/ = 596.7 A 3 , and Z = 2. Using x-ray diffuse scattering techniques we have established the Pt oxidation as +2.31 (2) from which the molecular formula Rb 2 [Pt(CN) 4 ]Cl/sub 0.31(2)/ . 3.0H 2 O is obtained. The structure consists of nearly planar Pt(CN) 4 moieties stacked along the c axis forming a perfectly linear Pt-Pt chain. The crystal asymmetric unit contains two independent Pt(CN) 4 1 . 7- groups, two H 2 O sites, one Rb + site, and one Cl - site. The asymmetric ordering of the Rb + ion and the H 2 O molecules constitutes the main source of crystal asymmetry. The two-independent Pt-Pt chain distances are definitely unequal (2.877 (8) and 2.924 (8) A) with the average intrachain separation (2.90 A) being slightly longer than in KCP(Br) (2.88 A) and KCP(Cl) (2.87 A). The replacement of K + by Rb + results in lattice expansion along c, which produces larger Pt-Pt intrachain separations. Thus the unequal and slightly longer Pt-Pt separations in RbCP(Cl), apparently result in increased electron localization along the Pt-atom chain and a concomitant decrease in the electrical conductivity. 10 figures, 3 tables

  10. Long Non-Coding RNAs Embedded in the Rb and p53 Pathways

    Energy Technology Data Exchange (ETDEWEB)

    Subramanian, Murugan; Jones, Matthew F.; Lal, Ashish, E-mail: ashish.lal@nih.gov [Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States)

    2013-12-04

    In recent years, long non-coding RNAs (lncRNAs) have gained significant attention as a novel class of gene regulators. Although a small number of lncRNAs have been shown to regulate gene expression through diverse mechanisms including transcriptional regulation, mRNA splicing and translation, the physiological function and mechanism of action of the vast majority are not known. Profiling studies in cell lines and tumor samples have suggested a potential role of lncRNAs in cancer. Indeed, distinct lncRNAs have been shown to be embedded in the p53 and Rb networks, two of the major tumor suppressor pathways that control cell cycle progression and survival. Given the fact that inactivation of Rb and p53 is a hallmark of human cancer, in this review we discuss recent evidence on the function of lncRNAs in the Rb and p53 signaling pathways.

  11. Long Non-Coding RNAs Embedded in the Rb and p53 Pathways

    International Nuclear Information System (INIS)

    Subramanian, Murugan; Jones, Matthew F.; Lal, Ashish

    2013-01-01

    In recent years, long non-coding RNAs (lncRNAs) have gained significant attention as a novel class of gene regulators. Although a small number of lncRNAs have been shown to regulate gene expression through diverse mechanisms including transcriptional regulation, mRNA splicing and translation, the physiological function and mechanism of action of the vast majority are not known. Profiling studies in cell lines and tumor samples have suggested a potential role of lncRNAs in cancer. Indeed, distinct lncRNAs have been shown to be embedded in the p53 and Rb networks, two of the major tumor suppressor pathways that control cell cycle progression and survival. Given the fact that inactivation of Rb and p53 is a hallmark of human cancer, in this review we discuss recent evidence on the function of lncRNAs in the Rb and p53 signaling pathways

  12. RB research reactor Safety Report

    International Nuclear Information System (INIS)

    Sotic, O.; Pesic, M.; Vranic, S.

    1979-04-01

    This RB reactor safety report is a revised and improved version of the Safety report written in 1962. It contains descriptions of: reactor building, reactor hall, control room, laboratories, reactor components, reactor control system, heavy water loop, neutron source, safety system, dosimetry system, alarm system, neutron converter, experimental channels. Safety aspects of the reactor operation include analyses of accident causes, errors during operation, measures for preventing uncontrolled activity changes, analysis of the maximum possible accident in case of different core configurations with natural uranium, slightly and highly enriched fuel; influence of possible seismic events

  13. Phosphorylation of pRb by cyclin D kinase is necessary for development of cardiac hypertrophy

    DEFF Research Database (Denmark)

    Hinrichsen, Rebecca; Hansen, A.H.; Haunsø, S.

    2008-01-01

    /6-phosphorylated retinoblastoma protein (pRb) during hypertrophy and expression of an unphosphorylatable pRb mutant impaired hypertrophic growth in cardiomyocytes. Transcription factor E2F was activated by hypertrophic elicitors but activation was impaired by pharmacological inhibition of cyclin D-cdk4...

  14. Phase formation in the Li2MoO4–Rb2MoO4–Fe2(MoO4)3 system and crystal structure of a novel triple molybdate LiRb2Fe(MoO4)3

    International Nuclear Information System (INIS)

    Khal'baeva, Klara M.; Solodovnikov, Sergey F.; Khaikina, Elena G.; Kadyrova, Yuliya M.; Solodovnikova, Zoya A.; Basovich, Olga M.

    2013-01-01

    X-ray investigation of solid state interaction of the components in the Li 2 MoO 4 –Rb 2 MoO 4 –Fe 2 (MoO 4 ) 3 system was carried out, and a subsolidus phase diagram of the said system was constructed. The subsystem Rb 2 MoO 4 –LiRbMoO 4 –RbFe(MoO 4 ) 2 was shown to be non-quasiternary. Formation of a novel triple molybdate LiRb 2 Fe(MoO 4 ) 3 was established, conditions of solid state synthesis and crystallization of the compound were found. Its crystal structure (orthorhombic, space group Pnma, Z=4, a=24.3956(6), b=5.8306(1), c=8.4368(2) Å) represents a new structure type and includes infinite two-row ribbons ([Fe(MoO 4 ) 3 ] 3− ) ∞ parallel to the b axis and composed of FeO 6 octahedra, terminal Mo(3)O 4 tetrahedra, and bridge Mo(1)O 4 and Mo(2)O 4 tetrahedra connecting two or three FeO 6 octahedra. The ribbons are connected to form 3D framework via corner-sharing LiO 4 tetrahedra. Rubidium cations are 11- and 13-coordinated and located in cavities of this heterogeneous polyhedral framework. - Graphical abstract: Exploring the Li 2 MoO 4 –Rb 2 MoO 4 –Fe 2 (MoO 4 ) 3 system showed its partial non-quasiternarity and revealed a new compound LiRb 2 Fe(MoO 4 ) 3 which was structurally studied. - Highlights: • The Li 2 MoO 4 –Rb 2 MoO 4 –Fe 2 (MoO 4 ) 3 system study revealed a new compound LiRb 2 Fe(MoO 4 ) 3 . • Its structure of a new type includes ribbons of FeO 6 octahedra and MoO 4 tetrahedra. • The ribbons are connected into a 3D framework via corner-sharing LiO 4 tetrahedra

  15. Effect of enzyme on extraction of ginsenoside Rb1 and Rg3 from Panax notoginseng roots

    Science.gov (United States)

    Phuong, Nguyen Tran Xuan; Thy, Lu Thi Mong; Khang, Nguyen Luu Vinh; My, Huynh Thi Kieu; Tam, Nguyen Le Phuong; Hieu, Nguyen Huu

    2018-04-01

    Panax notoginseng is distributed throughout the north and northwest of Vietnam, especially Ha Giang, Lao Cai, and Cao Bang provinces. The root of this plant contains ginsenosides (Rb1, Rb2, Rd, Rg3), flavonoids, polyacetylene, polysaccharides, amino acids, fatty acids, and peptides. In this study, the ratios of enzyme (Viscozyme, Termamyl, Cellulase), solvent of components, and time extraction were investigated. The results showed that the highest contents of Rb1 and Rg3 were achieved in the sample extracted with the ratio of enzymes V:C:T = 1:0:0, ethanol:water (60:40, v/v) as extracting solvent in 45 minutes. Then, conditions of high performance liquid chromatography with diode array detector method to determine the content of ginsenosides Rb1 and Rg3 in the roots of Panax notoginseng were studied, including wavelength, mobile phase, and flow rate. The separation was subjected on a reversed-phase C18 column using acetonitrile (A) and water (B) as mobile phase. The gradient elution was set as follow: 0-10 min, 15-25% A; 10-20 min, 25-30% A; 20-40 min, 30-60% A; 40-60 min, 60-80% A; and 60-65 min back to 15% A before the next injection, at a flow rate of 0.5 mL/min, and the wavelength was set at 202 nm. The linear range was from 298.59 to 696.72 µg/mL for Rb1 and from 8.19 to 19.10 µg/L for Rg3. The limits of detection for Rb1 and Rg3 obtained were 0.31 µg/mL and 0.33 µg/mL, respectively. The limits of quantification were 0.95 µg/mL and 1.01 µg/mL for Rb1 and Rg3, respectively. Consequently, the high performance liquid chromatography demonstrated the highly sensitive and accurate method for determination of Rb1 and Rg3 in Panax notoginseng.

  16. Immune Responses and Protection against Experimental Brucella suis biovar 1 Challenge in Non-vaccinated or RB51-Vaccinated Cattle

    Science.gov (United States)

    Twenty Hereford heifers, approximately 9 months of age, were vaccinated with saline (control) or 2 x 10**10 CFU of Brucella abortus strain RB51 (RB51) vaccine. Immunologic responses after inoculation demonstrated significantly greater (P<0.05) antibody and proliferative responses to RB51 antigens i...

  17. Rb-intercalated C{sub 60} compounds studied by photoemission spectroscopies

    Energy Technology Data Exchange (ETDEWEB)

    Brambilla, A [INFM - Dipartimento di Fisica, Politecnico di Milano, p.za L. da Vinci 32, I-20133 Milan (Italy); Giovanelli, L [Sincrotrone Trieste S.C.p.A., Strada Statale 14, Km 163.5, I-34012 Basovizza, Trieste (Italy); Vilmercati, P [Sincrotrone Trieste S.C.p.A., Strada Statale 14, Km 163.5, I-34012 Basovizza, Trieste (Italy); Cattoni, A [INFM - Dipartimento di Fisica, Politecnico di Milano, p.za L. da Vinci 32, I-20133 Milan (Italy); Biagioni, P [INFM - Dipartimento di Fisica, Politecnico di Milano, p.za L. da Vinci 32, I-20133 Milan (Italy); Goldoni, A [Sincrotrone Trieste S.C.p.A., Strada Statale 14, Km 163.5, I-34012 Basovizza, Trieste (Italy); Finazzi, M [INFM - Dipartimento di Fisica, Politecnico di Milano, p.za L. da Vinci 32, I-20133 Milan (Italy); Duo, L [INFM - Dipartimento di Fisica, Politecnico di Milano, p.za L. da Vinci 32, I-20133 Milan (Italy)

    2005-06-15

    We report on a combined photoemission and inverse photoemission spectroscopy analysis on Rb{sub x}C{sub 60} compounds with different stoichiometries (0-bar x-bar 6). Apart from shifts and broadening of the spectral features associated to the different phase formed, we observe in the RbC{sub 60} phase the presence of the highest occupied molecular orbital (HOMO) shoulder and of its symmetric (with respect to the Fermi level) empty state. According to calculations, the metallicity of this phase and the presence of these electronic states may be taken as a fingerprint of the interplay between electron-electron and electron-phonon interactions in determining the electronic behavior of alkali metal fullerides.

  18. Bose-Einstein condensate collapse: A comparison between theory and experiment

    International Nuclear Information System (INIS)

    Savage, C.M.; Robins, N.P.; Hope, J.J.

    2003-01-01

    We solve the Gross-Pitaevskii equation numerically for the collapse induced by a switch from positive to negative scattering lengths. We compare our results with experiments performed with Bose-Einstein condensates of 85 Rb, in which the scattering length was controlled using a Feshbach resonance. Building on previous theoretical work we identify quantitative differences between the predictions of mean-field theory and the results of the experiments. In addition to the previously reported difference between the predicted and observed critical atom number for collapse, we also find that the predicted collapse times systematically exceed those observed experimentally

  19. Doing Business Economy Profile 2015 : Venezuela, RB

    OpenAIRE

    World Bank Group

    2014-01-01

    This economy profile for Doing Business 2015 presents the 11 Doing Business indicators for Venezuela RB. To allow for useful comparison, the profile also provides data for other selected economies (comparator economies) for each indicator. Doing Business 2015 is the 12th edition in a series of annual reports measuring the regulations that enhance business activity and those that constrain ...

  20. Cu ion disordering in high ionic conductor Rb4Cu16I7Cl13

    International Nuclear Information System (INIS)

    Kawaji, Hitoshi; Atake, Tooru; Kanno, Ryoji; Izumi, Fujio; Yamamoto, Osamu.

    1993-01-01

    The properties of a high ionic conductor Rb 4 Cu 16 I 7+x Cl 13-x were studied by neutron and X-ray diffraction, and heat capacity measurements. The structure parameters of Rb 4 Cu 16 I 7.2 Cl 12.8 were obtained by the Rietveld analysis of TOF neutron diffraction data between 50 and 300 K, which showed gradual excitation of migration of Cu ions from Cu(3) site into Cu(2) site with increasing temperature from about 100 K to room temperature. The heat capacity was measured between 10 and 300 K using a high precision adiabatic calorimeter. An abnormal increase was observed in the heat capacity curve above about 100 K. The excess heat capacity showed a broad anomaly with a maximum at about 190 K. The measurements were also made of Rb 4 Cu 16 I 7 Cl 13 which showed slight different properties from Rb 4 Cu 16 I 7.2 Cl 12.8 . (author)

  1. Effect of shear stress on 86Rb+ efflux and cytosolic Ca2+ of calf pulmonary artery endothelial cells (CPAEs)

    International Nuclear Information System (INIS)

    Alevriadou, B.R.; Mo, M.; Rickman, D.S.; Eskin, S.G.; McIntire, L.V.; Schilling, W.P.

    1991-01-01

    The effect of flow-induced shear stress (SS) on membrane K + permeability and cytosolic free Ca 2+ , [Ca 2+ ] i , was investigated by measuring 86 Rb + efflux and fura-2 fluorescence in CPAEs using a parallel plate flow chamber. Increasing SS from 1 to 2.4, 4.8 or 10 dyn/cm 2 produced a graded, transient increase in 86 Rb + efflux which peaked within 1 min and subsequently declined rapidly towards pre-stimulus levels. Mathematical modeling confirmed that the transient increase in 86 Rb + efflux did not reflect a washout phenomenon. Upon returning SS to 1 dyn/cm 2 , 86 Rb + efflux initially decreased, but returned slowly to basal values. In contrast, application of bradykinin (BK) at a constant SS of either 0.33 or 1 dyn/cm 2 produced a transient increase in 86 Rb + efflux that was followed by a sustained elevated phase during which time efflux gradually returned to pre-stimulus levels. To determine the mechanism by which shear stress increases K + permeability, the effect of tetrabutylammonium ion (TBA), a selective inhibitor of Ca 2+ -dependent K + channels (K Ca ), on both the BK- and SS-induced increases in 86 Rb + efflux, was examined. TBA inhibited the BK-stimulated increase in 86 Rb + efflux >90% under both stationary and flow conditions and significantly reduced SS-dependent 86 Rb + efflux 38.3%. These results suggest that increased 86 Rb + efflux from CPAEs with SS occurs, at least in part, via K Ca and suggests that SS increases cytosolic Ca 2+ . However, when measured using fura-2-loaded CPAEs, SS was without significant effect on [Ca 2+ ] i

  2. Ginseng Rb fraction protects glia, neurons and cognitive function in a rat model of neurodegeneration.

    Directory of Open Access Journals (Sweden)

    Kangning Xu

    Full Text Available The loss and injury of neurons play an important role in the onset of various neurodegenerative diseases, while both microgliosis and astrocyte loss or dysfunction are significant causes of neuronal degeneration. Previous studies have suggested that an extract enriched panaxadiol saponins from ginseng has more neuroprotective potential than the total saponins of ginseng. The present study investigated whether a fraction of highly purified panaxadiol saponins (termed as Rb fraction was protective for both glia and neurons, especially GABAergic interneurons, against kainic acid (KA-induced excitotoxicity in rats. Rats received Rb fraction at 30 mg/kg (i.p., 40 mg/kg (i.p. or saline followed 40 min later by an intracerebroventricular injection of KA. Acute hippocampal injury was determined at 48 h after KA, and impairment of hippocampus-dependent learning and memory as well as delayed neuronal injury was determined 16 to 21 days later. KA injection produced significant acute hippocampal injuries, including GAD67-positive GABAergic interneuron loss in CA1, paralbumin (PV-positive GABAergic interneuron loss, pyramidal neuron degeneration and astrocyte damage accompanied with reactive microglia in both CA1 and CA3 regions of the hippocampus. There was also a delayed loss of GAD67-positive interneurons in CA1, CA3, hilus and dentate gyrus. Microgliosis also became more severe 21 days later. Accordingly, KA injection resulted in hippocampus-dependent spatial memory impairment. Interestingly, the pretreatment with Rb fraction at 30 or 40 mg/kg significantly protected the pyramidal neurons and GABAergic interneurons against KA-induced acute excitotoxicity and delayed injury. Rb fraction also prevented memory impairments and protected astrocytes from KA-induced acute excitotoxicity. Additionally, microglial activation, especially the delayed microgliosis, was inhibited by Rb fraction. Overall, this study demonstrated that Rb fraction protected both

  3. Immunological network activation by low-dose rate irradiation. Analysis of cell populations and cell surface molecules in whole body irradiated mice

    International Nuclear Information System (INIS)

    Ina, Yasuhiro; Sakai, Kazuo

    2003-01-01

    The effects of low-dose rate whole body irradiation on biodefense and immunological systems were investigated using female C57BL/6 (B6) mice. These B6 mice were exposed continuously to γ-rays from a 137 Cs source in the long-term low-dose rate irradiation facility at CRIEPI for 0 - 12 weeks at a dose rate of 0.95 mGy/hr. In the bone marrow, thymus, spleen, lymph nodes, and peripheral blood of the irradiated mice, changes in cell populations and cell surface molecules were examined. The cell surface functional molecules (CD3, CD4, CD8, CD19, CD45R/B220, ICAM-1, Fas, NK-1.1, CXCR4, and CCR5), and activation molecules (THAM, CD28, CD40, CD44H, CD70, B7-1, B7-2, OX-40 antigen, CTLA-4, CD30 ligand, and CD40 ligand) were analyzed by flow cytometry. The percentage of CD4 + T cells and cell surface CD8 molecule expressions on the CD8 + T cells increased significantly to 120-130% after 3 weeks of the irradiation, compared to non-irradiated control mice. On the other hand, the percentage of CD45R/B220 + CD40 + B cells, which is one of the immunological markers of inflammation, infection, tumor, and autoimmune disease, decreased significantly to 80-90% between the 3rd to 5th week of irradiation. There was no significant difference in other cell population rates and cell surface molecule expression. Furthermore, abnormal T cells bearing mutated T cell receptors induced by high-dose rate irradiation were not observed throughout this study. These results suggest that low-dose rate irradiation activates the immunological status of the whole body. (author)

  4. Pumilio and nanos RNA-binding proteins counterbalance the transcriptional consequences of RB1 inactivation.

    Science.gov (United States)

    Miles, Wayne O; Dyson, Nicholas J

    2014-01-01

    The ability of the retinoblastoma protein (RB) tumor suppressor to repress transcription stimulated by the E2 promoter binding factors (E2F) is integral to its biological functions. Our recent report described a conserved feedback mechanism mediated by the RNA-binding proteins Pumilio and Nanos that increases in importance following RB loss and helps cells to tolerate deregulated E2F.

  5. Uptake of 32P and 86Rb as influenced by temperature, transpiration suppress and shading treatment in rice plants

    International Nuclear Information System (INIS)

    Lee, G.B.; Hong, Y.P.; Im, J.N.; Chung, K.W.

    1989-01-01

    This study was carried out to know the uptake pattern of phosphorous and potassium in rice plants using by two radioisotopes, 32P and 86Rb as tracers for two years, 1987 and 1988. Rice plants were grown in the hydroponic culture with Yoshida's solution, and treated with different temperatures, transpiration suppress, shading, and phosphorous and potassium deletions. The uptake amount of 32P and 86Rb were increased with the increasing temperature in root sphere of rice plant, particularly remarkable increase of 86Rb uptake at 35deg C. The uptake of 32P tended to be promoted at the treatment of low air-high water temperature (17-30deg C), while that of 86Rb was not significantly differenced from different temperature treatments. The effect of transpiration on the uptake of 32P and 86Rb was extremely low. This phenomenon may suggest that the absorption be depending on active uptake rather than passive one by transpiration stream. The total carbohydrate contents of rice root were decreased by shading treatment, resulting significant reduction in the uptake of 32P and 86Rb. The uptake of 86Rb was remarkably increased in the treatment of potassium deletion, but that of 32P was not significantly increased in the delection of phosphorous

  6. Uptake of 32P and 86Rb as influenced by temperature, transpiration suppress and shading treatment in rice plants

    Energy Technology Data Exchange (ETDEWEB)

    Lee, G. B.; Hong, Y. P.; Im, J. N.; Chung, K. W.

    1989-07-01

    This study was carried out to know the uptake pattern of phosphorous and potassium in rice plants using by two radioisotopes, 32P and 86Rb as tracers for two years, 1987 and 1988. Rice plants were grown in the hydroponic culture with Yoshida's solution, and treated with different temperatures, transpiration suppress, shading, and phosphorous and potassium deletions. The uptake amount of 32P and 86Rb were increased with the increasing temperature in root sphere of rice plant, particularly remarkable increase of 86Rb uptake at 35deg C. The uptake of 32P tended to be promoted at the treatment of low air-high water temperature (17-30deg C), while that of 86Rb was not significantly differenced from different temperature treatments. The effect of transpiration on the uptake of 32P and 86Rb was extremely low. This phenomenon may suggest that the absorption be depending on active uptake rather than passive one by transpiration stream. The total carbohydrate contents of rice root were decreased by shading treatment, resulting significant reduction in the uptake of 32P and 86Rb. The uptake of 86Rb was remarkably increased in the treatment of potassium deletion, but that of 32P was not significantly increased in the delection of phosphorous.

  7. 75 FR 801 - Airworthiness Directives; Rolls-Royce plc RB211-Trent 500, 700, and 800 Series Turbofan Engines

    Science.gov (United States)

    2010-01-06

    ...The FAA proposes to supersede an existing airworthiness directive (AD) for Rolls-Royce plc RB211-Trent 800 series turbofan engines. That AD currently requires replacing the fuel-to-oil heat exchanger (FOHE). This proposed AD would require replacing the FOHE on the RB211-Trent 500 and RB211-Trent 700 series turbofan engines in addition to the RB211-Trent 800 series turbofan engines. This proposed AD results from mandatory continuing airworthiness information (MCAI) issued by an aviation authority of another country to identify and correct an unsafe condition on an aviation product, and results from the risk of engine FOHE blockage. The MCAI describes the unsafe condition as:

  8. Crystal structure of RbCe(SeO4)2 · 5H2O

    International Nuclear Information System (INIS)

    Ovanesyan, S.M.; Iskhakova, L.D.; Trunov, V.K.

    1987-01-01

    RbTR(SeO 4 ) 2 x5H 2 O TR=La-Pr are synthesized. Crystal structure of RbCe(SeO 4 ) 2 x5H 2 O is studied. Monoclinic unit parameters are: a=7,200(2), b=8,723(1), c=19,258(6) A, Β=90,88(2), ρ (calc) =3,304 sp.gr. P2 1 /c. Within the structure the Ce nine vertex cages are united by Se(1)- and Se(2)-tetrahedrons in (Ce(SeO 4 ) 2 (H 2 O) 5 ) 2 ∞ n- layers. Some crystal structure regularities of the laminated MTR(EO 4 ) 2 xnH 2 O (M=NH 4 ,K,Rb,Cs; TR=La-Ln, E=S,Se) are considered

  9. Independent fission yields of Rb and Cs from thermal-neutron-induced fission of 239Pu

    International Nuclear Information System (INIS)

    Balestrini, S.J.; Forman, L.

    1975-01-01

    The relative independent fission yields of Rb and Cs from thermal-neutron-induced fission of 239 Pu have been measured on line using a mass spectrograph and thermalized neutrons from a burst reactor. Independent yields were derived by normalizing the measurements to products of chain yields and fractional independent yields, estimating the latter from measured cumulative yields of Kr and Xe. Comparing the independent yields with those from 238 U fission, the 239 Pu results show shifts in isotopic yield distribution toward lower mass for both Rb and Cs and also toward the production of more Cs and less Rb when 239 Pu is fissioned

  10. The tumor suppressors pRB and p53 as regulators of adipocyte differentiation and function

    DEFF Research Database (Denmark)

    Hallenborg, Philip; Feddersen, Søren; Madsen, Lise

    2009-01-01

    BACKGROUND: The retinoblastoma protein (pRB) and p53 are crucial members of regulatory networks controlling the cell cycle and apoptosis, and a hallmark of virtually all cancers is dysregulation of expression or function of pRB or p53. Although they are best known for their role in cancer...

  11. Hypothalamic growth hormone receptor (GHR controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb expressing neurons

    Directory of Open Access Journals (Sweden)

    Gillian Cady

    2017-05-01

    Full Text Available Objective: The GH/IGF-1 axis has important roles in growth and metabolism. GH and GH receptor (GHR are active in the central nervous system (CNS and are crucial in regulating several aspects of metabolism. In the hypothalamus, there is a high abundance of GH-responsive cells, but the role of GH signaling in hypothalamic neurons is unknown. Previous work has demonstrated that the Ghr gene is highly expressed in LepRb neurons. Given that leptin is a key regulator of energy balance by acting on leptin receptor (LepRb-expressing neurons, we tested the hypothesis that LepRb neurons represent an important site for GHR signaling to control body homeostasis. Methods: To determine the importance of GHR signaling in LepRb neurons, we utilized Cre/loxP technology to ablate GHR expression in LepRb neurons (LeprEYFPΔGHR. The mice were generated by crossing the Leprcre on the cre-inducible ROSA26-EYFP mice to GHRL/L mice. Parameters of body composition and glucose homeostasis were evaluated. Results: Our results demonstrate that the sites with GHR and LepRb co-expression include ARH, DMH, and LHA neurons. Leptin action was not altered in LeprEYFPΔGHR mice; however, GH-induced pStat5-IR in LepRb neurons was significantly reduced in these mice. Serum IGF-1 and GH levels were unaltered, and we found no evidence that GHR signaling regulates food intake and body weight in LepRb neurons. In contrast, diminished GHR signaling in LepRb neurons impaired hepatic insulin sensitivity and peripheral lipid metabolism. This was paralleled with a failure to suppress expression of the gluconeogenic genes and impaired hepatic insulin signaling in LeprEYFPΔGHR mice. Conclusion: These findings suggest the existence of GHR-leptin neurocircuitry that plays an important role in the GHR-mediated regulation of glucose metabolism irrespective of feeding. Keywords: Growth hormone receptor, Hypothalamus, Leptin receptor, Glucose production, Liver

  12. Alterations of 86Rb+ fluxes in poliovirus-infected HeLa cells and their dependence on virus replication

    International Nuclear Information System (INIS)

    Schaefer, A.; Geck, P.; Zibirre, R.; Kuehne, J.; Koch, G.

    1984-01-01

    Components of the 86Rb+ influx were investigated subsequent to poliovirus infection in the presence and absence of guanidine-HCl, both under normal steady-state conditions and after Na+ preloading of the cells. Measurements of the ouabain-sensitive 86Rb+ uptake indicated a biphasic change in the activity of the Na+, K+ pump in the course of virus infection: a transient increase in the second hour postinfection, that was detectable only after Na+ preloading and inhibition after 3 hr. The enhanced activity of the Na+, K+ pump was not affected, while the decrease later was fully prevented by the antiviral agent guanidine-HCl. The piretanide-sensitive 86Rb+ uptake due to the Na+, K+, 2 Cl- cotransport system also became strongly inhibited beginning in the second hour postinfection. The inhibition of this transport system was partially antagonized by guanidine-HCl. The remaining 86Rb+ influx in the presence of ouabain and piretanide increased in the third hour postinfection. The latter change in 86Rb+ influx, indicating an increased permeability to monovalent cations was completely abolished by guanidine-HCl

  13. Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons.

    Science.gov (United States)

    Cady, Gillian; Landeryou, Taylor; Garratt, Michael; Kopchick, John J; Qi, Nathan; Garcia-Galiano, David; Elias, Carol F; Myers, Martin G; Miller, Richard A; Sandoval, Darleen A; Sadagurski, Marianna

    2017-05-01

    The GH/IGF-1 axis has important roles in growth and metabolism. GH and GH receptor (GHR) are active in the central nervous system (CNS) and are crucial in regulating several aspects of metabolism. In the hypothalamus, there is a high abundance of GH-responsive cells, but the role of GH signaling in hypothalamic neurons is unknown. Previous work has demonstrated that the Ghr gene is highly expressed in LepRb neurons. Given that leptin is a key regulator of energy balance by acting on leptin receptor (LepRb)-expressing neurons, we tested the hypothesis that LepRb neurons represent an important site for GHR signaling to control body homeostasis. To determine the importance of GHR signaling in LepRb neurons, we utilized Cre/loxP technology to ablate GHR expression in LepRb neurons (Lepr EYFPΔGHR ). The mice were generated by crossing the Lepr cre on the cre-inducible ROSA26-EYFP mice to GHR L/L mice. Parameters of body composition and glucose homeostasis were evaluated. Our results demonstrate that the sites with GHR and LepRb co-expression include ARH, DMH, and LHA neurons. Leptin action was not altered in Lepr EYFPΔGHR mice; however, GH-induced pStat5-IR in LepRb neurons was significantly reduced in these mice. Serum IGF-1 and GH levels were unaltered, and we found no evidence that GHR signaling regulates food intake and body weight in LepRb neurons. In contrast, diminished GHR signaling in LepRb neurons impaired hepatic insulin sensitivity and peripheral lipid metabolism. This was paralleled with a failure to suppress expression of the gluconeogenic genes and impaired hepatic insulin signaling in Lepr EYFPΔGHR mice. These findings suggest the existence of GHR-leptin neurocircuitry that plays an important role in the GHR-mediated regulation of glucose metabolism irrespective of feeding.

  14. Refractometry of LiRbSO4 crystals

    International Nuclear Information System (INIS)

    Stadnyk, V.Y.; Romanyuk, M.O.; Karplyuk, L.T.

    2004-01-01

    Making use of the Obreimov photographic method, the dependences of birefringence Δn i of LiRbSO 4 crystals have been studied in wide spectral (250-800 nm) and temperature (100 - 600 K) ranges, as well as the influence of uniaxial mechanical stresses on them. The anomalies of Δn i at successive phase transitions, namely, paraelectric - incommensurate - commensurate ferroelastic - ferroelectric - paraelectric phases, have been discovered

  15. The refractometry of the mechanically stressed RbNH4SO4 crystals

    International Nuclear Information System (INIS)

    Stadnik, V.J.; Romanyuk, M.O.

    2001-01-01

    The temperature (77-300K) and spectral (300-700hm) dependencies of refractive indices n i of mechanically unstressed and stressed by the pressures along general crystallophysic directions RbNH 4 SO 4 crystals were studied.the refractive indices were observed to decrease under pressure.The temperature and spectral dependencies of piezooptic constants were investigated.The changes of refraction,electron polarizability and the position of ultraviolet absorption effective center were calculated.The temperature and spectral dependencies of birefringence sign inversion of the mechanically unstressed and stressed RbNH 4 SO 4 crystals were analyzed

  16. Study of the excitation bands in 75Br and 77Rb

    International Nuclear Information System (INIS)

    Luehmann, L.

    1985-01-01

    Via the compound-nucleus reactions 62 Ni( 16 O,p2n) 75 Br, 66 Zn( 12 C,p2n) 75 Br, and 40 Ca( 40 Ca,3p) 77 Rb the excitation behaviour of the nuclei 75 Br and 77 Rb was studied. By the application of different gamma-spectroscopic methods as the measurement of γ angular anisotropies, nγ-spectra, excitation functions, and γγ-coincidences the known level schemes could be extended by 10 respectively 16 transitions. Recoil-distance Doppler-shift and Doppler-shift attenuation measurements served for the determination of the lifetimes of 42 nuclear states in the range 0.1 ps [de

  17. Operation and maintenance of the RB reactor, Annual report for 1980

    International Nuclear Information System (INIS)

    Sotic, O.; Vranic, S.; Markovic, H.; Zivkovic, B.; Gogdanovic, M.; Petronijevic, M.

    1980-12-01

    This report includes data concerned with reactor operation and utilization, status of reactor components and equipment, refurbishment of the equipment, dosimetry and radiation protection, reactor staff, financing. It includes 9 Annexes as follows: Utilization of the RB reactor from 1976 - 1980; program of reactor utilization from 1981-1985; contents of the RB reactor safety report; maintenance of the reactor components and equipment in 1980; verification of reactor reliability after the earthquake (May 18 1980); refurbishment of equipment in 1980, and purchasing new equipment from 1981-1985; review of radiation doses in the reactor building and exposure doses for the reactor staff; personnel data and financial data

  18. Magnetic properties of the alkali metal ozonides KO3, RbO3, and CsO3

    International Nuclear Information System (INIS)

    Lueken, H.; Deussen, M.; Jansen, M.; Hesse, W.; Schnick, W.

    1987-01-01

    The magnetic susceptibilities of KO 3 , RbO 3 and CsO 3 have been determined between 3.6 and 250 K. Above 50 K Curie-Weiss behaviour is observed. Magnetic moments of 1.74 μ B (KO 3 , CsO 3 ) and 1.80 μ B (RbO 3 ) calculated from the Curie-Weiss straight lines correspond with spin-only moments expected for isolated O 3 - species with one unpaired electron. The Weiss constants Θ are -34 K (KO 3 ), -23 K (RbO 3 ) and -10 K (CsO 3 ). The low temperature behaviour of KO 3 and RbO 3 (broad maxima in susceptibility at 20 and 17 K, respectively, and minima at 6 K) is typical of systems which show with decreasing temperature low-dimensional antiferromagnetic and three-dimensional magnetic ordering. Inspecting the intermolecular distances between oxygen atoms the pathways of exchange interactions are discussed. (author)

  19. Cellphone-based detection platform for rbST biomarker analysis in milk extracts using a microsphere fluorescence immunoassay.

    Science.gov (United States)

    Ludwig, Susann K J; Zhu, Hongying; Phillips, Stephen; Shiledar, Ashutosh; Feng, Steve; Tseng, Derek; van Ginkel, Leendert A; Nielen, Michel W F; Ozcan, Aydogan

    2014-11-01

    Current contaminant and residue monitoring throughout the food chain is based on sampling, transport, administration, and analysis in specialized control laboratories. This is a highly inefficient and costly process since typically more than 99% of the samples are found to be compliant. On-site simplified prescreening may provide a scenario in which only samples that are suspect are transported and further processed. Such a prescreening can be performed using a small attachment on a cellphone. To this end, a cellphone-based imaging platform for a microsphere fluorescence immunoassay that detects the presence of anti-recombinant bovine somatotropin (rbST) antibodies in milk extracts was developed. RbST administration to cows increases their milk production, but is illegal in the EU and a public health concern in the USA. The cellphone monitors the presence of anti-rbST antibodies (rbST biomarker), which are endogenously produced upon administration of rbST and excreted in milk. The rbST biomarker present in milk extracts was captured by rbST covalently coupled to paramagnetic microspheres and labeled by quantum dot (QD)-coupled detection antibodies. The emitted fluorescence light from these captured QDs was then imaged using the cellphone camera. Additionally, a dark-field image was taken in which all microspheres present were visible. The fluorescence and dark-field microimages were analyzed using a custom-developed Android application running on the same cellphone. With this setup, the microsphere fluorescence immunoassay and cellphone-based detection were successfully applied to milk sample extracts from rbST-treated and untreated cows. An 80% true-positive rate and 95% true-negative rate were achieved using this setup. Next, the cellphone-based detection platform was benchmarked against a newly developed planar imaging array alternative and found to be equally performing versus the much more sophisticated alternative. Using cellphone-based on-site analysis in

  20. 75 FR 15321 - Airworthiness Directives; Rolls-Royce plc RB211-Trent 800 Series Turbofan Engines

    Science.gov (United States)

    2010-03-29

    ... Directives; Rolls-Royce plc RB211-Trent 800 Series Turbofan Engines AGENCY: Federal Aviation Administration... Based on the service information, we estimate that this AD will affect about 138 RB211 Trent 800 series... will cost about $2,000 per engine. Based on these figures, we estimate the cost of the AD on U.S...

  1. Number-Theory in Nuclear-Physics in Number-Theory: Non-Primality Factorization As Fission VS. Primality As Fusion; Composites' Islands of INstability: Feshbach-Resonances?

    Science.gov (United States)

    Siegel, Edward

    2011-10-01

    Numbers: primality/indivisibility/non-factorization versus compositeness/divisibility /factor-ization, often in tandem but not always, provocatively close analogy to nuclear-physics: (2 + 1)=(fusion)=3; (3+1)=(fission)=4[=2 × 2]; (4+1)=(fusion)=5; (5 +1)=(fission)=6[=2 × 3]; (6 + 1)=(fusion)=7; (7+1)=(fission)=8[= 2 × 4 = 2 × 2 × 2]; (8 + 1) =(non: fission nor fusion)= 9[=3 × 3]; then ONLY composites' Islands of fusion-INstability: 8, 9, 10; then 14, 15, 16,... Could inter-digit Feshbach-resonances exist??? Applications to: quantum-information/computing non-Shore factorization, millennium-problem Riemann-hypotheses proof as Goodkin BEC intersection with graph-theory ``short-cut'' method: Rayleigh(1870)-Polya(1922)-``Anderson'' (1958)-localization, Goldbach-conjecture, financial auditing/accounting as quantum-statistical-physics;... abound!!!

  2. A gravimetric and an X-ray fluorescence method for the determination of rubidium in Rb2U(SO4)3

    International Nuclear Information System (INIS)

    Mudher, K.D.S.; Krishnan, K.; Jayadevan, N.C.

    1993-01-01

    Chemical characterization of rubidium uranium(IV) trisulfate, RB 2 U(SO 4 ) 3 , a new chemical assay standard for uranium requires accurate analysis of rubidium. A gravimetric and an X-ray fluorescence method (XRF) for the determination of rubidium in this compound are described. In the gravimetric method, rubidium is determined as Rb 2 Na[Co(NO 2 ) 6 ].H 2 O without separating uranium with a precision of the order of ±0.5%. In the XRF method, the concentration ratio of rubidium to uranium, C Rb /C U , is determined in the solid samples by the binary ratio method using calibration between intensity ratios (I Rb /I U ) and concentration ratios (C Rb /C U ). (author) 6 refs.; 2 figs.; 3 tabs

  3. Rayleigh scattering of Moessbauer radiation in superionic conductor RbAg/sub 4/I/sub 5/

    Energy Technology Data Exchange (ETDEWEB)

    Ovanesyan, N.S.; Goffman, V.G.; Sokolov, V.B.; Tkachev, V.V. (AN SSSR, Chernogolovka. Otdelenie Inst. Khimicheskoj Fiziki)

    1984-04-01

    The dynamical properties of RbAg/sub 4/I/sub 5/ has been investiaated by Rayleigh scattering of Moessbauer radiation (RSMR) with wave-length lambda = 0.86 A. The character of Ag/sup +/ ion oscillatory motion and diffusion in RbAg/sub 4/I/sub 5/ depending on temperature including the phase transitions region is studied. It is shown that in the superionic crystal RbAg/sub 4/I/sub 5/ the diffusion process is strongly correlated, i.e. a great number of initial and final states at diffusion jumps coincide. The observed broadening can be less than the expected one by value orders. Diffusion correlation can strongly reduce the activation barrier and lead to anomalously high ionic conduction.

  4. RB962962, a sugarcane cultivar for late harvest

    Directory of Open Access Journals (Sweden)

    Luiz José Oliveira Tavares de Melo

    2014-07-01

    Full Text Available In the Northeast of Brazil, sugarcane cultivar RB962962 is harvested at the end of the cycle, between December and February, with a high sugar yield per area. Recommended for sandy soils of medium texture and fertility, it is resistant to the major diseases and fast-growing in plant and ratoon crops.

  5. /sup 86/Rb uptake of various organs of the spontaneously hypertensive rats

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, M; Kuroiwa, A; Nakagaki, O; Tomoike, H; Nose, Y [Kyushu Univ., Fukuoka (Japan). Faculty of Medicine

    1975-03-01

    Twenty spontaneously hypertensive rats (SHR) and 20 control rats were used for the measurement of Rb/sup 86/ uptake by various organs. Hemodynamic measurements, and the heart weight to body weight ratio showed a significant and sustained hypertension with an increased heart rate in SHR. The ratio of the Rb/sup 86/ uptake in the kidney, brain, liver, adrenal gland, pancreas, and spleen to that in the right ventricle (RV) was smaller in SHR than it was in the control rats. The ratio of the Rb/sup 86/ uptake of the inner layer to the outer layer of the left ventricle (LV), which represents distribution of blood flow to the endocardial layer and epicardial layer, showed no difference between SHR and the control rats. The regional flow fraction in the outer and inner cortex, juxtamedulla, and medulla of the kidney showed no difference between SHR and the control. The present preliminary study suggests that the myocardial blood flow in SHR is greater than that in the control rats. The relationship between cardiac hypertrophy and myocardial flow was discussed.

  6. Bayesian Penalized Likelihood Image Reconstruction (Q.Clear) in 82Rb Cardiac PET: Impact of Count Statistics

    DEFF Research Database (Denmark)

    Christensen, Nana Louise; Tolbod, Lars Poulsen

    PET scans. 3) Static and dynamic images from a set of 7 patients (BSA: 1.6-2.2 m2) referred for 82Rb cardiac PET was analyzed using a range of beta factors. Results were compared to the institution’s standard clinical practice reconstruction protocol. All scans were performed on GE DMI Digital......Aim: Q.Clear reconstruction is expected to improve detection of perfusion defects in cardiac PET due to the high degree of image convergence and effective noise suppression. However, 82Rb (T½=76s) possess a special problem, since count statistics vary significantly not only between patients...... statistics using a cardiac PET phantom as well as a selection of clinical patients referred for 82Rb cardiac PET. Methods: The study consistent of 3 parts: 1) A thorax-cardiac phantom was scanned for 10 minutes after injection of 1110 MBq 82Rb. Frames at 3 different times after infusion were reconstructed...

  7. Tunable High Q Superconducting Microwave Resonator for Hybrid System with ^87Rb atoms

    Science.gov (United States)

    Kim, Zaeill; Voigt, K. D.; Lee, Jongmin; Hoffman, J. E.; Grover, J. A.; Ravets, S.; Zaretskey, V.; Palmer, B. S.; Hafezi, M.; Taylor, J. M.; Anderson, J. R.; Dragt, A. J.; Lobb, C. J.; Orozco, L. A.; Rolston, S. L.; Wellstood, F. C.

    2012-02-01

    We have developed a frequency tuning system for a ``lumped-element'' thin-film superconducting Al microwave resonator [1] on sapphire intended for coupling to hyperfine ground states of cold trapped ^87Rb atoms, which are separated by about fRb=6.83 GHz. At T=12 mK and on resonance at 6.81 GHz, the loaded quality factor was 120,000. By moving a carefully machined Al pin towards the inductor of the resonator using a piezo stage, we were able to tune the resonance frequency over a range of 35 MHz and within a few kHz of fRb. While measuring the power dependent response of the resonator at each tuned frequency, we observed anomalous decreases in the quality factor at several frequencies. These drops were more pronounced at lower power. We discuss our results, which suggest these resonances are attributable to discrete two-level systems.[4pt] [1] Z. Kim et al., AIP ADVANCES 1, 042107 (2011).

  8. Tet1 is required for Rb phosphorylation during G1/S phase transition

    International Nuclear Information System (INIS)

    Huang, Shengsong; Zhu, Ziqi; Wang, Yiqin; Wang, Yanru; Xu, Longxia; Chen, Xuemei; Xu, Qing; Zhang, Qimin; Zhao, Xin; Yu, Yi; Wu, Denglong

    2013-01-01

    Highlights: •Tet1 was required for NIT3T3 proliferation. •Tet1 depletion inhibited G1-S entry. •Cyclin D1 accumulation and Rb phosphorylation was blocked by Tet1 knockdown. -- Abstract: DNA methylation plays an important role in many biological processes, including regulation of gene expression, maintenance of chromatin conformation and genomic stability. TET-family proteins convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which indicates that these enzymes may participate in DNA demethylation. The function of TET1 has not yet been well characterized in somatic cells. Here, we show that depletion of Tet1 in NIH3T3 cells inhibits cell growth. Furthermore, Tet1 knockdown blocks cyclin D1 accumulation in G1 phase, inhibits Rb phosphorylation and consequently delays entrance to G1/S phase. Taken together, this study demonstrates that Tet1 is required for cell proliferation and that this process is mediated through the Rb pathway

  9. Common window resonance features in K and heavier alkaline atoms Rb and Cs

    International Nuclear Information System (INIS)

    Koide, Michi; Koike, Fumihiro; Nagata, Tetsuo

    2002-01-01

    A previous study of subvalence s-shell photoionization of potassium [Koide et al.: J. Phys. Soc. Jpn. 71 (2002) 1676] has been extended to the cases of heavier alkaline atoms Rb and Cs. We have measured the photoion time-of-flight spectra using monochromatized synchrotron radiation. Dual windows resonance structure previously observed in K was also found in Rb and Cs, suggesting that those structure are general features in alkaline atoms. We have observed also the Rydberg series of resonances that appear in dual windows. Our data analysis shows that the resonance widths are broad when compared with its rare gas neighbors. Based on multiconfiguration Dirac-Fock calculations, the Rydberg series of resonances were assigned to the 4s 1 4p 6 5s5p excitations embedded in the 4p 5 5s continua for Rb and to the 5s 1 5p 6 6s6p excitations embedded in the 5p 5 6s continua for Cs. (author)

  10. Deregulation of p53 and RB Transcriptional Control Leads to Overexpression of DNA Methyltransferases in Lung Cancer

    Directory of Open Access Journals (Sweden)

    Yen-An Tang

    2014-06-01

    Conclusions: This study provides cell and clinical evidence that p53 and RB pathways transcriptionally repress DNMT expression. Normal expression of DNMT3A, RB and MDM2 proteins can be a biomarker for good prognosis in lung cancer.

  11. Rotational dynamics of C60 in Na2RbC60

    International Nuclear Information System (INIS)

    Christides, C.; Prassides, K.; Neumann, D.A.; Copley, J.R.D.; Mizuki, J.; Tanigaki, K.; Hirosawa, I.; Ebbesen, T.W.

    1993-01-01

    We have measured the low-energy neutron inelastic-scattering (NIS) spectra of superconducting Na 2 RbC 60 in the temperature range 50-350 K. Well-defined librational peaks are observed at 50 K at 2.83(17) meV (FWHM = 1.7(5) meV). They soften and broaden with increasing temperature. Their behaviour mimics that found in solid C 60 and differs markedly from K 3 C 60 . The rotational barrier for C 60 reorientations in Na 2 RbC 60 is somewhat higher than in pristine C 60 and approximately half as large as in K 3 C 60 . An order-disorder transition is anticipated at a temperature higher than that found in C 60 . (orig.)

  12. Topologically identical, but geometrically isomeric layers in hydrous α-, β-Rb[UO{sub 2}(AsO{sub 3}OH)(AsO{sub 2}(OH){sub 2})]·H{sub 2}O and anhydrous Rb[UO{sub 2}(AsO{sub 3}OH)(AsO{sub 2}(OH){sub 2})

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Na; Klepov, Vladislav V. [Forschungszentrum Jülich GmbH, Institute for Energy and Climate Research (IEK-6), 52428 Jülich (Germany); Villa, Eric M. [Department of Chemistry, Creighton University, 2500 California Plaza, Omaha NE 68178 (United States); Bosbach, Dirk [Forschungszentrum Jülich GmbH, Institute for Energy and Climate Research (IEK-6), 52428 Jülich (Germany); Suleimanov, Evgeny V. [Department of Chemistry, Lobachevsky State University of Nizhny Novgorod, 603950 Nizhny Novgorod (Russian Federation); Depmeier, Wulf [Institut für Geowissenschaften, Universität zu Kiel, 24118 Kiel (Germany); Albrecht-Schmitt, Thomas E., E-mail: albrecht-schmitt@chem.fsu.edu [Department of Chemistry and Biochemistry, Florida State University, 102 Varsity Way, Tallahassee, FL 32306-4390 (United States); Alekseev, Evgeny V., E-mail: e.alekseev@fz-juelich.de [Forschungszentrum Jülich GmbH, Institute for Energy and Climate Research (IEK-6), 52428 Jülich (Germany); Institut für Kristallographie, RWTH Aachen University, 52066 Aachen (Germany)

    2014-07-01

    The hydrothermal reaction of uranyl nitrate with rubidium nitrate and arsenic (III) oxide results in the formation of polymorphic α- and β-Rb[UO{sub 2}(AsO{sub 3}OH)(AsO{sub 2}(OH){sub 2})]·H{sub 2}O (α-, β-RbUAs) and the anhydrous phase Rb[UO{sub 2}(AsO{sub 3}OH)(AsO{sub 2}(OH){sub 2})] (RbUAs). These phases were structurally, chemically and spectroscopically characterized. The structures of all three compounds are based upon topologically identical, but geometrically isomeric layers. The layers are linked with each other by means of the Rb cations and hydrogen bonding. Dehydration experiments demonstrate that water deintercalation from hydrous α- and β-RbUAs yields anhydrous RbUAs via topotactic reactions. - Graphical abstract: Three different layer geometries observed in the structures of Rb[UO{sub 2}(AsO{sub 3}OH)(AsO{sub 2}(OH){sub 2})] and α- and β- Rb[UO{sub 2}(AsO{sub 3}OH)(AsO{sub 2}(OH){sub 2})]·H{sub 2}O. Two different coordination environments of uranium polyhedra (types I and II) are shown schematically on the top of the figure. - Highlights: • Three new uranyl arsenates were synthesized from the hydrothermal reactions. • The phases consist of the topologically identical but geometrically different layers. • Topotactic transitions were observed in the processes of mono-hyrates dehydration.

  13. Abortion and premature birth in cattle following vaccination with Brucella abortus strain RB51.

    Science.gov (United States)

    Fluegel Dougherty, Amanda M; Cornish, Todd E; O'Toole, Donal; Boerger-Fields, Amy M; Henderson, Owen L; Mills, Ken W

    2013-09-01

    Brucella abortus RB51 is the vaccine strain currently licensed for immunizing cattle against brucellosis in the United States. Most cattle are vaccinated as heifer calves at 4-12 months of age. Adult cattle may be vaccinated in selected high-risk situations. Two herds of pregnant adult cattle in the brucellosis-endemic area of Wyoming were vaccinated with a standard label dose (1.0-3.4 × 10(10) organisms) of RB51. Reproductive losses in the vaccinated herds were 5.3% (herd A) and 0.6% (herd B) and included abortions, stillbirths, premature calves, and unbred cows (presumed early abortion). Brucella abortus was cultured from multiple tissues of aborted and premature calves (7/9), and from placenta. Isolates were identified as B. abortus strain RB51 by standard strain typing procedures and a species-specific polymerase chain reaction. Bronchopneumonia with intralesional bacteria and placentitis were observed microscopically. There was no evidence of involvement of other infectious or toxic causes of abortion. Producers, veterinarians, and laboratory staff should be alert to the risk of abortion when pregnant cattle are vaccinated with RB51, to potential human exposure, and to the importance of distinguishing field from vaccinal strains of B. abortus.

  14. HAGRID/ VANDLE spectroscopy of Rb decays

    Science.gov (United States)

    King, Thomas; Grzywacz, Robert; Taylor, Steven; Paulauskas, Stanley; Smith, Karl; Vandle Collaboration

    2017-09-01

    Many neutron-rich isotopes that contribute in both decay heat production and r-process nucleosynthesis have substantial beta-delayed neutron branching ratios. Beta-delayed neutron emission is a relatively complicated mechanism which can leave the daughter in an gamma-emitting excited state. A comprehensive understanding of their energy output and decay strength, S_beta, therefore requires the detection of both neutrons and gamma rays in coincidence. A series of measurements of delayed neutron precursors were performed at the On-Line Test Facility (OLTF) at the Oak Ridge National Laboratories using chemically selective ion sources and an enhanced VANDLE array. The main goal of this experiment was to revisit the decays of IAEA-marked priority precursors, including bromine, rubidium, cesium, and iodine, that are required to model the global properties in the fission of 238U.The unique data set, with neutron and gamma ray coincidences, benefited from the addition of a high-efficiency gamma-ray array, consisting of 16 LaBr3 crystals (HAGRiD), and a set of large volume NaI detectors to the VANDLE array. Characterization of and preliminary results from the new gamma-ray array for the decays of 94Rb and 97Rb will be presented. National Nuclear Security Administration under the Stewardship Science Academic Alliances program through DOE Award No. DE-NA0002132 and the Office of Nuclear Physics, U.S. Department of Energy under Award No. DE-FG02-96ER40983.

  15. $\\gamma$ -spectroscopy of n-rich $^{95,96}$Rb nuclei by the incomplete fusion reaction of $^{94}$Kr on $^{7}$Li

    CERN Multimedia

    We propose an experiment with MINIBALL coupled to T-REX to investigate n-rich $^{95,96}$Rb nuclei by the incomplete fusion reaction of $^{94}$Kr on $^{7}$Li. The nuclei of interest will be populated by transfer of a triton into $^{94}$Kr, forming the excited $^{97}$Rb nucleus, followed by the emission of an alpha particle, which will be detected in the Si telescopes of T-REX. The $^{97}$Rb product will evaporate 1 or 2 (with the highest probability) neutrons leading to $^{96}$Rb or $^{95}$Rb, respectively. The aim of the experiment is twofold: \\\\ i) to perform a $\\gamma$- spectroscopy study of $^{95,96}$Rb nuclei with N=58,59, the structure of which is of particular interest in investigating the transition towards stable deformation at N=60, \\\\ ii) to acquire experience in using incomplete fusion reactions with the weakly bound $^{7}$Li target, in order to perform, at a later stage with HIE-ISOLDE, similar measurements induced by n-rich radioactive beams of Sn and Hg, for which at least 5 MeV/nucleon are need...

  16. NMR investigation of charge fluctuations in the charge-density-wave (CDW) system Rb_0.3MoO_3

    Science.gov (United States)

    Tanaka, K. B.; Vonlanthen, P.; Clark, W. G.; Kriza, G.; Moulton, W. G.; Kuhns, P.; Reyes, A. P.

    2001-03-01

    We report measurements of the spin-lattice relaxation rate (T_1-1), the spin-spin relaxation rate (T_2-1), and NMR spectra of ^85Rb and ^87Rb in Rb_0.3MoO3 for the temperature (T) range 5-300 K at 9 T and 23 T. The ratio of T_1-1 for ^85Rb and ^87Rb shows that for all T, the dominant coupling for T_1-1 is quadrupolar; i.e., it is driven by charge fluctuations. Prior work assumed that in the metallic phase above 182 K, the relaxation was via magnetic coupling to conduction electrons. Another surprising result is the absence of a strong variation of T_1-1 across the CDW-broadened spectrum. Such a variation is expected for relaxation by thermal CDW phason fluctuations. Our high field measurements also show very little frequency dependence for T_1-1. The observed T-variation of T_1-1 displays five different regimes, which will be presented and discussed. The UCLA part of the work was supported by NSF Grants DMR-9705369 and DMR-0072524.

  17. Insight into the architecture of the NuRD complex: structure of the RbAp48-MTA1 subcomplex.

    Science.gov (United States)

    Alqarni, Saad S M; Murthy, Andal; Zhang, Wei; Przewloka, Marcin R; Silva, Ana P G; Watson, Aleksandra A; Lejon, Sara; Pei, Xue Y; Smits, Arne H; Kloet, Susan L; Wang, Hongxin; Shepherd, Nicholas E; Stokes, Philippa H; Blobel, Gerd A; Vermeulen, Michiel; Glover, David M; Mackay, Joel P; Laue, Ernest D

    2014-08-08

    The nucleosome remodeling and deacetylase (NuRD) complex is a widely conserved transcriptional co-regulator that harbors both nucleosome remodeling and histone deacetylase activities. It plays a critical role in the early stages of ES cell differentiation and the reprogramming of somatic to induced pluripotent stem cells. Abnormalities in several NuRD proteins are associated with cancer and aging. We have investigated the architecture of NuRD by determining the structure of a subcomplex comprising RbAp48 and MTA1. Surprisingly, RbAp48 recognizes MTA1 using the same site that it uses to bind histone H4, showing that assembly into NuRD modulates RbAp46/48 interactions with histones. Taken together with other results, our data show that the MTA proteins act as scaffolds for NuRD complex assembly. We further show that the RbAp48-MTA1 interaction is essential for the in vivo integration of RbAp46/48 into the NuRD complex. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

  18. Feasibility study of applying reactor oscillator phase method at the RB reactor; Razmatranje mogucnosti primene fazne metode reaktorskog oscilatora na reaktoru RB

    Energy Technology Data Exchange (ETDEWEB)

    Petrovic, M; Kocic, A; Markovic, V [Institute of Nuclear Sciences Boris Kidric, Vinca, Beograd (Yugoslavia)

    1965-11-15

    This paper decsribes the principles of amplitude and phase methods for applying reactor oscillator; experimental procedure and choice of optimum parameters for usractor oscillator at the RB reactor, dependent on the values of absorption properties of moderator and construction materials. Short description of the oscillator and the electronic equipment is included.

  19. Measurement of control rods efficiency at the RB reactor by pulse method; Merenje efikasnosti kontrolnih sipki u reaktoru RB impulsnom metodom

    Energy Technology Data Exchange (ETDEWEB)

    Petrovic, M; Markovic, V; Velickovic, Lj [Boris Kidric Institute of nuclear sciences, Vinca, Belgrade (Yugoslavia)

    1963-07-01

    Pulse method was applied for measuring the efficiency of control rods at the RB reactor. This paper describes the theory of experiment, experimental procedure applied and results obtained. Results are considered to be useful for safety analysis. it was found that the influence of delayed neutrons is rather small and could be neglected in estimation of rods efficiency.

  20. Clinicopathological significance of p16, cyclin D1, Rb and MIB-1 levels in skull base chordoma and chondrosarcoma

    Directory of Open Access Journals (Sweden)

    Jun-qi Liu

    2015-09-01

    Full Text Available Objective: To investigate the expression of p16, cyclin D1, retinoblastoma tumor suppressor protein (Rb and MIB-1 in skull base chordoma and chondrosarcoma tissues, and to determine the clinicopathological significance of the above indexes in these diseases. Methods: A total of 100 skull base chordoma, 30 chondrosarcoma, and 20 normal cartilage tissue samples were analyzed by immunohistochemistry. The expression levels of p16, cyclinD1, Rb and MIB-1 proteins were assessed for potential correlation with the clinicopathological features. Results: As compared to normal cartilage specimen (control, there was decreased expression of p16, and increased expression of cyclin D1, Rb and MIB-1 proteins, in both skull base chordoma and chondrosarcoma specimens. MIB-1 LI levels were significantly increased in skull base chordoma specimens with negative expression of p16, and positive expression of cyclin D1 and Rb (P  0.05. However, p16 and MIB-1 levels correlated with the intradural invasion, and expression of p16, Rb and MIB-1 correlated with the number of tumor foci (P < 0.05. Further, the expression of p16 and MIB-1 appeared to correlate with the prognosis of patients with skull base chordoma. Conclusions: The abnormal expression of p16, cyclin D1 and Rb proteins might be associated with the tumorigenesis of skull base chordoma and chondrosarcoma. Keywords: p16, Cyclin D1, Rb, MIB-1, Skull base chordoma, Skull base chondrosarcoma

  1. RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells.

    Science.gov (United States)

    Hesbacher, Sonja; Pfitzer, Lisa; Wiedorfer, Katharina; Angermeyer, Sabrina; Borst, Andreas; Haferkamp, Sebastian; Scholz, Claus-Jürgen; Wobser, Marion; Schrama, David; Houben, Roland

    2016-05-31

    The pocket protein (PP) family consists of the three members RB1, p107 and p130 all possessing tumor suppressive properties. Indeed, the PPs jointly control the G1/S transition mainly by inhibiting E2F transcription factors. Notably, several viral oncoproteins are capable of binding and inhibiting PPs. Merkel cell polyomavirus (MCPyV) is considered as etiological factor for Merkel cell carcinoma (MCC) with expression of the viral Large T antigen (LT) harboring an intact PP binding domain being required for proliferation of most MCC cells. Therefore, we analyzed the interaction of MCPyV-LT with the PPs. Co-IP experiments indicate that MCPyV-LT binds potently only to RB1. Moreover, MCPyV-LT knockdown-induced growth arrest in MCC cells can be rescued by knockdown of RB1, but not by p107 or p130 knockdown. Accordingly, cell cycle arrest and E2F target gene repression mediated by the single PPs can only in the case of RB1 be significantly reverted by MCPyV-LT expression. Moreover, data from an MCC patient indicate that loss of RB1 rendered the MCPyV-positive MCC cells LT independent. Thus, our results suggest that RB1 is the dominant tumor suppressor PP in MCC, and that inactivation of RB1 by MCPyV-LT is largely sufficient for its growth supporting function in established MCPyV-positive MCC cells.

  2. Ginsenoside Rb1 Reduces Nitric Oxide Production via Inhibition of ...

    African Journals Online (AJOL)

    Inhibition of Nuclear Factor-κB Activation in Interleukin-1β- ... 20, 40, 80 µM ginsenoside Rb1. NO concentration was assessed by the Griess reaction. ... International Pharmaceutical Abstract, Chemical Abstracts, Embase, Index Copernicus, ...

  3. Magnetic moment of the 9/2[sup +] 96. 4 keV state in [sup 79] Rb

    Energy Technology Data Exchange (ETDEWEB)

    Dumitru, M; Ionescu-Bujor, M; Iordachescu, A; Ivan, A; Ivanov, E A; Pascovici, G; Plostinaru, D [Institute of Atomic Physics, Institute of Physics and Nuclear Engineering, R-76900 Bucharest, P.O.Box MG-6, (Romania)

    1992-01-01

    The region of nuclei with A [approx equal] 80 is presently of considerable interest as it exhibits a rich variety of phenomena. In the present work, part of a programme of structure investigation in this region through electromagnetic moment measurements, we have determined the magnetic moment of the 9/2[sup +] 96.4 keV state in [sup 79] Rb. The state has been excited by the [sup 79] Br ([sup 3] He , 3 n) reaction on a K Br target with cubic structure, using a 30 MeV pulsed beam of [sup 3] He provided by a U-120 cyclotron. The measurements have been performed by the TDPAD method at several different values of the external magnetic field. From our investigations the half-life T[sub 1/2] = 18.5(5) ns and the gyromagnetic ratio g = +1.12(5) have been established for the 9/2[sup +] 96.4 keV state. The band properties of the odd Rb nuclei indicated a gradual change of the structure along the isotopes, the [sup 79] Rb nucleus being characterized by a deformation significantly larger than that of heavier once. This change in structure is also reflected in the g factor values of the low-lying 9/2[sup +] states, which show a monotonic decrease from [sup 85] Rb to [sup 79] Rb. (Author).

  4. Hydrogen-Bonding Capability of a Templating Difluorotoluene Nucleotide Residue in an RB69 DNA Polymerase Ternary Complex

    Energy Technology Data Exchange (ETDEWEB)

    Xia, Shuangluo; Konigsberg, William H.; Wang, Jimin (Yale)

    2011-08-29

    Results obtained using 2,4-difluorotoluene nucleobase (dF) as a nonpolar thymine isostere by Kool and colleagues challenged the Watson-Crick dogma that hydrogen bonds between complementary bases are an absolute requirement for accurate DNA replication. Here, we report crystal structure of an RB69 DNA polymerase L561A/S565G/Y567A triple mutant ternary complex with a templating dF opposite dTTP at 1.8 {angstrom}-resolution. In this structure, direct hydrogen bonds were observed between: (i) dF and the incoming dTTP, (ii) dF and residue G568 of the polymerase, and (iii) dF and ordered water molecules surrounding the nascent base pair. Therefore, this structure provides evidence that a templating dF can form novel hydrogen bonds with the incoming dTTP and with the enzyme that differ from those formed with a templating dT.

  5. 76 FR 78805 - Airworthiness Directives; Rolls-Royce plc (RR) RB211-Trent 800 Series Turbofan Engines

    Science.gov (United States)

    2011-12-20

    ... Airworthiness Directives; Rolls-Royce plc (RR) RB211-Trent 800 Series Turbofan Engines AGENCY: Federal Aviation... all Rolls-Royce plc (RR) RB211-Trent 800 Series Turbofan Engines. This AD results from mandatory... inspection of the FOHE mounts. We did not change the AD based on this comment. Request To Add Requirement To...

  6. The immunological response of RB51 vaccinated buffalo calves ...

    African Journals Online (AJOL)

    Immune status of RB51 vaccinated buffaloes was evaluated using tube agglutination test (TAT) and ELISA, using both periplasmic protein antigen (PPA) and lipopolysaccharide antigen (LPS). For this purpose, three groups of buffalo calves were used. The first one received S19 vaccine subcutaneously; the second was ...

  7. Unusual centrosymmetric structure of [M(18-crown-6)](+) (M = Rb, Cs and NH4) complexes stabilized in an environment of hexachloridoantimonate(V) anions.

    Science.gov (United States)

    Ponomarova, Vira V; Rusanova, Julia A; Rusanov, Eduard B; Domasevitch, Konstantin V

    2015-10-01

    In (1,4,7,10,13,16-hexaoxacyclooctadecane)rubidium hexachloridoantimonate(V), [Rb(C12H24O6)][SbCl6], (1), and its isomorphous caesium {(1,4,7,10,13,16-hexaoxacyclooctadecane)caesium hexachloridoantimonate(V), [Cs(C12H24O6)][SbCl6]}, (2), and ammonium {ammonium hexachloridoantimonate(V)-1,4,7,10,13,16-hexaoxacyclooctadecane (1/1), (NH4)[SbCl6]·C12H24O6}, (3), analogues, the hexachloridoantimonate(V) anions and 18-crown-6 molecules reside across -3 axes passing through the Sb atoms and the centroids of the 18-crown-6 groups, both of which coincide with centres of inversion. The Rb(+) [in (1)], Cs(+) [in (2)] and NH4(+) [in (3)] cations are situated inside the cavity of the 18-crown-6 ring; they are situated on -3 axes and are equally disordered about centres of inversion, deviating from the centroid of the 18-crown-6 molecule by 0.4808 (13), 0.9344 (7) and 0.515 (8) Å, respectively. Interaction of the ammonium cation and the 18-crown-6 group is supported by three equivalent hydrogen bonds [N...O = 2.928 (3) Å and N-H...O = 162°]. The centrosymmetric structure of [Cs(18-crown-6)](+), with the large Cs(+) cation approaching the centre of the ligand cavity, is unprecedented and accompanied by unusually short Cs-O bonds [2.939 (2) and 3.091 (2) Å]. For all three compounds, the [M(18-crown-6)](+) cations and [SbCl6](-) anions afford linear stacks along the c axis, with the cationic complexes embedded between pairs of inversion-related anions.

  8. Overexpression of Brucella putative glycosyltransferase WbkA in B. abortus RB51 leads to production of exopolysaccharide.

    Science.gov (United States)

    Dabral, Neha; Jain-Gupta, Neeta; Seleem, Mohamed N; Sriranganathan, Nammalwar; Vemulapalli, Ramesh

    2015-01-01

    Brucella spp. are Gram-negative, facultative intracellular bacteria that cause brucellosis in mammals. Brucella strains containing the O-polysaccharide in their cell wall structure exhibit a smooth phenotype whereas the strains devoid of the polysaccharide show rough phenotype. B. abortus strain RB51 is a stable rough attenuated mutant which is used as a licensed live vaccine for bovine brucellosis. Previous studies have shown that the wboA gene, which encodes a glycosyltransferase required for the synthesis of O-polysaccharide, is disrupted in B. abortus RB51 by an IS711 element. Although complementation of strain RB51 with a functional wboA gene results in O-polysaccharide synthesis in the cytoplasm, it does not result in smooth phenotype. The aim of this study was to determine if overexpression of Brucella WbkA or WbkE, two additional putative glycosyltransferases essential for O-polysaccharide synthesis, in strain RB51 would result in the O-polysaccharide synthesis and smooth phenotype. Our results demonstrate that overexpression of wbkA or wbkE gene in RB51 does not result in O-polysaccharide expression as shown by Western blotting with specific antibodies. However, wbkA, but not wbkE, overexpression leads to the development of a clumping phenotype and the production of exopolysaccharide(s) containing mannose, galactose, N-acetylglucosamine, and N-acetylgalactosamine. Moreover, we found that the clumping recombinant strain displays increased adhesion to polystyrene plates. The recombinant strain was similar to strain RB51 in its attenuation characteristic and in its ability to induce protective immunity against virulent B. abortus challenge in mice.

  9. Neuroprotective effects of ginsenoside Rb1 on high glucose-induced neurotoxicity in primary cultured rat hippocampal neurons.

    Science.gov (United States)

    Liu, Di; Zhang, Hong; Gu, Wenjuan; Liu, Yuqin; Zhang, Mengren

    2013-01-01

    Ginsenoside Rb1 is one of the main active principles in traditional herb ginseng and has been reported to have a wide variety of neuroprotective effects. Endoplasmic reticulum (ER) stress has been implicated in neurodegenerative diseases, so the present study aimed to observe the effects of ginsenoside Rb1 on ER stress signaling pathways in high glucose-treated hippocampal neurons. The results from MTT, TUNEL labeling and Annexin V-FITC/PI/Hoechst assays showed that incubating neurons with 50 mM high glucose for 72 h decreased cell viability and increased the number of apoptotic cells whereas treating neurons with 1 μM Rb1 for 72 h protected the neurons against high glucose-induced cell damage. Further molecular mechanism study demonstrated that Rb1 suppressed the activation of ER stress-associated proteins including protein kinase RNA (PKR)-like ER kinase (PERK) and C/EBP homology protein (CHOP) and downregulation of Bcl-2 induced by high glucose. Moreover, Rb1 inhibited both the elevation of intracellular reactive oxygen species (ROS) and the disruption of mitochondrial membrane potential induced by high glucose. In addition, the high glucose-induced cell apoptosis, activation of ER stress, ROS accumulation and mitochondrial dysfunction can also be attenuated by the inhibitor of ER stress 4-phenylbutyric acid (4-PBA) and anti-oxidant N-acetylcysteine(NAC). In conclusion, these results suggest that Rb1 may protect neurons against high glucose-induced cell injury through inhibiting CHOP signaling pathway as well as oxidative stress and mitochondrial dysfunction.

  10. Mimicking multichannel scattering with single-channel approaches

    Science.gov (United States)

    Grishkevich, Sergey; Schneider, Philipp-Immanuel; Vanne, Yulian V.; Saenz, Alejandro

    2010-02-01

    The collision of two atoms is an intrinsic multichannel (MC) problem, as becomes especially obvious in the presence of Feshbach resonances. Due to its complexity, however, single-channel (SC) approximations, which reproduce the long-range behavior of the open channel, are often applied in calculations. In this work the complete MC problem is solved numerically for the magnetic Feshbach resonances (MFRs) in collisions between generic ultracold Li6 and Rb87 atoms in the ground state and in the presence of a static magnetic field B. The obtained MC solutions are used to test various existing as well as presently developed SC approaches. It was found that many aspects even at short internuclear distances are qualitatively well reflected. This can be used to investigate molecular processes in the presence of an external trap or in many-body systems that can be feasibly treated only within the framework of the SC approximation. The applicability of various SC approximations is tested for a transition to the absolute vibrational ground state around an MFR. The conformance of the SC approaches is explained by the two-channel approximation for the MFR.

  11. Mimicking multichannel scattering with single-channel approaches

    International Nuclear Information System (INIS)

    Grishkevich, Sergey; Schneider, Philipp-Immanuel; Vanne, Yulian V.; Saenz, Alejandro

    2010-01-01

    The collision of two atoms is an intrinsic multichannel (MC) problem, as becomes especially obvious in the presence of Feshbach resonances. Due to its complexity, however, single-channel (SC) approximations, which reproduce the long-range behavior of the open channel, are often applied in calculations. In this work the complete MC problem is solved numerically for the magnetic Feshbach resonances (MFRs) in collisions between generic ultracold 6 Li and 87 Rb atoms in the ground state and in the presence of a static magnetic field B. The obtained MC solutions are used to test various existing as well as presently developed SC approaches. It was found that many aspects even at short internuclear distances are qualitatively well reflected. This can be used to investigate molecular processes in the presence of an external trap or in many-body systems that can be feasibly treated only within the framework of the SC approximation. The applicability of various SC approximations is tested for a transition to the absolute vibrational ground state around an MFR. The conformance of the SC approaches is explained by the two-channel approximation for the MFR.

  12. Apollo 17 'melt sheet': chemistry, age and Rb/Sr systematics

    Energy Technology Data Exchange (ETDEWEB)

    Winzer, S R [Martin Marietta Labs., Baltimore, Md. (USA); Nava, D F; Schuhmann, S; Philpotts, J A [National Aeronautics and Space Administration, Greenbelt, Md. (USA). Goddard Space Flight Center; Schuhmann, P J; Lum, R K.L.; Lindstrom, M M; Lindstrom, D J [Maryland Univ., College Park (USA)

    1977-01-01

    Major, minor and trace element compositions, age data and Rb/Sr systematics of Apollo 17 boulders have been compiled, and additional analyses performed on a norite breccia clast (77215) included in the Apollo 17, Station 7 boulder. The Apollo 17 boulders are found to be identical or nearly so in major, minor and trace element composition, suggesting that they all originated as an impact melt analogous to melt sheets found in larger terrestrial craters. The matrix dates (/sup 40/Ar//sup 39/Ar) and Rb/Sr systematics available suggest that this impact melt formed by a single impact about 4 b.y. ago. This impact excavated, shocked, brecciated and melted norites, norite cumulates and possibly anorthositic gabbros and dunites about 4.4 b.y. old. The impact was likely a major one, possibly the Serenitatis basin-forming event.

  13. Measurement of $R_{b}$ and $B_{r}(b \\to l\

    CERN Document Server

    Acciarri, M.; Adriani, O.; Aguilar-Benitez, M.; Alcaraz, J.; Alemanni, G.; Allaby, J.; Aloisio, A.; Alviggi, M.G.; Ambrosi, G.; Anderhub, H.; Andreev, Valery P.; Angelescu, T.; Anselmo, F.; Arefev, A.; Azemoon, T.; Aziz, T.; Bagnaia, P.; Baksay, L.; Balandras, A.; Ball, R.C.; Banerjee, S.; Banerjee, Sw.; Barczyk, A.; Barillere, R.; Barone, L.; Bartalini, P.; Basile, M.; Battiston, R.; Bay, A.; Becattini, F.; Becker, U.; Behner, F.; Bellucci, L.; Berdugo, J.; Berges, P.; Bertucci, B.; Betev, B.L.; Bhattacharya, S.; Biasini, M.; Biland, A.; Blaising, J.J.; Blyth, S.C.; Bobbink, G.J.; Bohm, A.; Boldizsar, L.; Borgia, B.; Bourilkov, D.; Bourquin, M.; Braccini, S.; Branson, J.G.; Brigljevic, V.; Brochu, F.; Buffini, A.; Buijs, A.; Burger, J.D.; Burger, W.J.; Busenitz, J.; Button, A.; Cai, X.D.; Campanelli, Mario; Capell, M.; Cara Romeo, G.; Carlino, G.; Cartacci, A.M.; Casaus, J.; Castellini, G.; Cavallari, F.; Cavallo, N.; Cecchi, C.; Cerrada, M.; Cesaroni, F.; Chamizo, M.; Chang, Y.H.; Chaturvedi, U.K.; Chemarin, M.; Chen, A.; Chen, G.; Chen, G.M.; Chen, H.F.; Chen, H.S.; Chereau, X.; Chiefari, G.; Cifarelli, L.; Cindolo, F.; Civinini, C.; Clare, I.; Clare, R.; Coignet, G.; Colijn, A.P.; Colino, N.; Costantini, S.; Cotorobai, F.; Cozzoni, B.; de la Cruz, B.; Csilling, A.; Cucciarelli, S.; Dai, T.S.; van Dalen, J.A.; D'Alessandro, R.; de Asmundis, R.; Deglon, P.; Degre, A.; Deiters, K.; Della Volpe, D.; Denes, P.; De Notaristefani, F.; De Salvo, A.; Diemoz, M.; van Dierendonck, D.; Di Lodovico, F.; Dionisi, C.; Dittmar, M.; Dominguez, A.; Doria, A.; Dova, M.T.; Duchesneau, D.; Dufournaud, D.; Duinker, P.; Duran, I.; El Mamouni, H.; Engler, A.; Eppling, F.J.; Erne, F.C.; Extermann, P.; Fabre, M.; Faccini, R.; Falagan, M.A.; Falciano, S.; Favara, A.; Fay, J.; Fedin, O.; Felcini, M.; Ferguson, T.; Ferroni, F.; Fesefeldt, H.; Fiandrini, E.; Field, J.H.; Filthaut, F.; Fisher, P.H.; Fisk, I.; Forconi, G.; Fredj, L.; Freudenreich, K.; Furetta, C.; Galaktionov, Iouri; Ganguli, S.N.; Garcia-Abia, Pablo; Gataullin, M.; Gau, S.S.; Gentile, S.; Gheordanescu, N.; Giagu, S.; Gong, Z.F.; Grenier, Gerald Jean; Grimm, O.; Gruenewald, M.W.; Guida, M.; van Gulik, R.; Gupta, V.K.; Gurtu, A.; Gutay, L.J.; Haas, D.; Hasan, A.; Hatzifotiadou, D.; Hebbeker, T.; Herve, Alain; Hidas, P.; Hirschfelder, J.; Hofer, H.; Holzner, G.; Hoorani, H.; Hou, S.R.; Iashvili, I.; Jin, B.N.; Jones, Lawrence W.; de Jong, P.; Josa-Mutuberria, I.; Khan, R.A.; Kamrad, D.; Kaur, M.; Kienzle-Focacci, M.N.; Kim, D.; Kim, D.H.; Kim, J.K.; Kim, S.C.; Kirkby, Jasper; Kiss, D.; Kittel, W.; Klimentov, A.; Konig, A.C.; Kopp, A.; Korolko, I.; Koutsenko, V.; Kraber, M.; Kraemer, R.W.; Krenz, W.; Kunin, A.; Ladron de Guevara, P.; Laktineh, I.; Landi, G.; Lassila-Perini, K.; Laurikainen, P.; Lavorato, A.; Lebeau, M.; Lebedev, A.; Lebrun, P.; Lecomte, P.; Lecoq, P.; Le Coultre, P.; Lee, H.J.; Le Goff, J.M.; Leiste, R.; Leonardi, Emanuele; Levtchenko, P.; Li, C.; Lin, C.H.; Lin, W.T.; Linde, F.L.; Lista, L.; Liu, Z.A.; Lohmann, W.; Longo, E.; Lu, Y.S.; Lubelsmeyer, K.; Luci, C.; Luckey, David; Lugnier, L.; Luminari, L.; Lustermann, W.; Ma, W.G.; Maity, M.; Malgeri, L.; Malinin, A.; Mana, C.; Mangeol, D.; Marchesini, P.; Marian, G.; Martin, J.P.; Marzano, F.; Massaro, G.G.G.; Mazumdar, K.; McNeil, R.R.; Mele, S.; Merola, L.; Meschini, M.; Metzger, W.J.; von der Mey, M.; Mihul, A.; Milcent, H.; Mirabelli, G.; Mnich, J.; Mohanty, G.B.; Molnar, P.; Monteleoni, B.; Moulik, T.; Muanza, G.S.; Muheim, F.; Muijs, A.J.M.; Musy, M.; Napolitano, M.; Nessi-Tedaldi, F.; Newman, H.; Niessen, T.; Nisati, A.; Kluge, Hannelies; Oh, Y.D.; Organtini, G.; Ostonen, R.; Palomares, C.; Pandoulas, D.; Paoletti, S.; Paolucci, P.; Paramatti, R.; Park, H.K.; Park, I.H.; Pascale, G.; Passaleva, G.; Patricelli, S.; Paul, Thomas Cantzon; Pauluzzi, M.; Paus, C.; Pauss, F.; Peach, D.; Pedace, M.; Pensotti, S.; Perret-Gallix, D.; Petersen, B.; Piccolo, D.; Pierella, F.; Pieri, M.; Piroue, P.A.; Pistolesi, E.; Plyaskin, V.; Pohl, M.; Pojidaev, V.; Postema, H.; Pothier, J.; Produit, N.; Prokofev, D.O.; Prokofev, D.; Quartieri, J.; Rahal-Callot, G.; Rahaman, M.A.; Raics, P.; Raja, N.; Ramelli, R.; Rancoita, P.G.; Raven, G.; Razis, P.; Ren, D.; Rescigno, M.; Reucroft, S.; van Rhee, T.; Riemann, S.; Riles, Keith; Robohm, A.; Rodin, J.; Roe, B.P.; Romero, L.; Rosca, A.; Rosier-Lees, S.; Rubio, J.A.; Ruschmeier, D.; Rykaczewski, H.; Sarkar, S.; Salicio, J.; Sanchez, E.; Sanders, M.P.; Sarakinos, M.E.; Schafer, C.; Shchegelskii, V.; Schmidt-Kaerst, S.; Schmitz, D.; Schopper, H.; Schotanus, D.J.; Schwering, G.; Sciacca, C.; Sciarrino, D.; Seganti, A.; Servoli, L.; Shevchenko, S.; Shivarov, N.; Shoutko, V.; Shumilov, E.; Shvorob, A.; Siedenburg, T.; Son, D.; Smith, B.; Spillantini, P.; Steuer, M.; Stickland, D.P.; Stone, A.; Stone, H.; Stoyanov, B.; Straessner, A.; Sudhakar, K.; Sultanov, G.; Sun, L.Z.; Suter, H.; Swain, J.D.; Szillasi, Z.; Sztaricskai, T.; Tang, X.W.; Tauscher, L.; Taylor, L.; Timmermans, Charles; Ting, S.C.C.; Ting, S.M.; Tonwar, S.C.; Toth, J.; Tully, C.; Tung, K.L.; Uchida, Y.; Ulbricht, J.; Valente, E.; Vesztergombi, G.; Vetlitskii, I.; Vicinanza, D.; Viertel, G.; Villa, S.; Vivargent, M.; Vlachos, S.; Vodopianov, I.; Vogel, H.; Vogt, H.; Vorobev, I.; Vorobov, A.A.; Vorvolakos, A.; Wadhwa, M.; Wallraff, W.; Wang, M.; Wang, X.L.; Wang, Z.M.; Weber, A.; Weber, M.; Wienemann, P.; Wilkens, H.; Wu, S.X.; Wynhoff, S.; Xia, L.; Xu, Z.Z.; Yang, B.Z.; Yang, C.G.; Yang, H.J.; Yang, M.; Ye, J.B.; Yeh, S.C.; Zalite, A.; Zalite, Yu.; Zhang, Z.P.; Zhu, G.Y.; Zhu, R.Y.; Zichichi, A.; Ziegler, F.; Zilizi, G.; Zoller, M.

    2000-01-01

    We present a combined measurement of $\\Rb = \\Gamma(\\mathrm{Z \\rightarrow b\\overline{b}}) / \\Gamma(\\mathrm{Z} \\rightarrow\\mbox{hadro ns})$ and the semileptonic branching ratio of b quarks in Z decays, $\\Brbl$, using double-tag methods. Two analyses are performed on one million hadronic Z decays collected in 1994 and 1995. The first analysis exploits the capabilities of the silicon microvertex detector. The tagging of b-events is based on the large impact parameter of tracks from weak b-decays with respect to the $\\mathrm{e^+e^-}$ collision point. In the second analysis, a high-$p_t$ lepton tag is used to enhance the b-component in the sample and its momentum spectrum is used to constrain the model dependent uncertainties in the semileptonic b-decay. The analyses are combined in order to provide precise determinations of $\\Rb$ and $\\Brbl$:

  14. Complexing in the system Rb2SeO4-UO2SeO4-H2O

    International Nuclear Information System (INIS)

    Kuchumova, N.V.; Shtokova, I.P.; Serezhkina, L.B.; Serezhkin, V.N.

    1989-01-01

    Method of isothermal solubility at 25 deg C is used to study interaction of rubidium and uranyl selenates in aqueous solution. Formation of congruently soluble Rb 2 UO 2 (SeO 4 ) 2 x2H 2 O and Rb 2 (UO 2 ) 2 x(SeO 4 ) 3 x6H 2 O is stated. For the last compound crystallographic characteristics (a=10.668; b=14.935(9); c=13.891(7) A; β=104.94(1); Z=4, sp.gr. P2 1 /c) are determined. Thermal decomposition of a compound results in formation of Rb 2 U 2 O 7

  15. Rapid detection of RB1 recurrent mutations in retinoblastoma by ...

    Indian Academy of Sciences (India)

    In about half of the patients, one mutation is inherited via the germinal cells, while in the .... mutational hot spots in the RB1 gene, making genetic testing complex and challenging ... by direct sequencing. High normal background in sequenc-.

  16. Investigation of the weathering effect on Rb-Sr systematics and trace element abundances in Antarctic and non-Antarctic meteorites

    International Nuclear Information System (INIS)

    Nishikawa, Yoshiyuki; Nakamura, Noboru; Misawa, Keiji; Okano, Osamu; Yamamoto, Koshi; Kagami, Hiroo.

    1990-01-01

    In order to examine weathering effects on chondritic meteorites in Antarctic and non-Antarctic environments, the Rb-Sr isotopic ratios and abundances of REE, Ba, Sr, Rb, and K were determined for 8H-group chondrites (Yamato-790986 [H3], Yamato-74492 [H3], Grady [H3], Brownfield [H3], Clovis (No.1) [H3], Yamato-74155 [H4], Allegan [H5] [one whole-rock and two chondrules], and Yamato-74371 [H5]), and partly for the Etter (L5) chondrite. The Allegan whole-rock shows a flat REE pattern with a large negative Eu anomaly and Sr depletion. Analyses of Rb-Sr systematics of one whole-rock and two chondrules show somewhat younger age 4.38±0.12 b.y. It is suggested that REE and Rb-Sr were redistributed during the early thermal metamorphism. Except for Allegan, most other H-chondrites (finds) show the perturbation of the Rb-Sr systematics, indicating recent loss of Rb. It was found that the weathering degree is related with the Rb-Sr disturbance in Antarctic H-chondrite. In spite of different degrees of weathering, all the Antarctic H-chondrites studied (including heavily weathered ones) show flat REE patterns normal as H-chondrite with occasional occurrence of minor Eu anomalies, indicating the tough resistance of REE in H-chondrites to the Antarctic weathering. On the other hand, non-Antarctic finds (particularly the weathered chondrites) indicate light-REE enriched patterns with a large negative Ce anomaly and extreme enrichment of Ba, suggestive of terrestrial contaminations. (author)

  17. Phenomenological study of nuclear structure of neutron-rich 88Rb isotope

    Science.gov (United States)

    Gupta, Surbhi; Gupta, Anuradha; Bharti, Arun

    2018-05-01

    A theoretical study of the nuclear structure of odd-odd 88Rb nucleus in the A ˜100 mass region is carried out by using the angular-momentum-projection technique implemented in the Projected Shell Model (PSM). The influence of the high-j orbitals, h11/2 for neutrons and g9/2 for protons on the structure of 88Rb isotope is investigated in the present case by assuming an axial symmetry in the deformed basis. For this isotope, PSM calculations are performed to obtain the yrast line and also the description of the formation of the yrast level structure from multi-quasi-particle configurations. The back-bending in moment of inertia and transition energies have also been calculated and compared with the experimental data.

  18. Laser cooling of 85Rb atoms to the recoil-temperature limit

    Science.gov (United States)

    Huang, Chang; Kuan, Pei-Chen; Lan, Shau-Yu

    2018-02-01

    We demonstrate the laser cooling of 85Rb atoms in a two-dimensional optical lattice. We follow the two-step degenerate Raman sideband cooling scheme [Kerman et al., Phys. Rev. Lett. 84, 439 (2000), 10.1103/PhysRevLett.84.439], where a fast cooling of atoms to an auxiliary state is followed by a slow cooling to a dark state. This method has the advantage of independent control of the heating rate and cooling rate from the optical pumping beam. We operate the lattice at a Lamb-Dicke parameter η =0.45 and show the cooling of spin-polarized 85Rb atoms to the recoil temperature in both dimensions within 2.4 ms with the aid of adiabatic cooling.

  19. Population of delayed-neutron granddaughter states and the optical potential

    International Nuclear Information System (INIS)

    Schenter, R.E.; Mann, F.M.; Warner, R.A.; Reeder, P.L.

    1982-08-01

    Using a statistical treatment of beta decay and the Hauser-Feshbach model of nuclear reactions, calculations were made and compared to recent experimental measurements of the population of granddaughter states of several delayed neutron precursors ( 144 145 147 Cs and 96 Rb). Emphasis of this paper is on the sensitivity and interpretation of experimental results to various standard low energy neutron optical model potentials and variations in their forms and parameters. Results for these precursors show qualitative agreement with experiment for all the optical potential models used and good quantitative agreement for two (Moldauer and Becchetti-Greenlees). Questions such as (N-Z) terms, deformation and nonlocality dependence are presented

  20. Structure determination, electronic and optical properties of rubidium holmium polyphosphate RbHo(PO3)4

    Science.gov (United States)

    Zhu, Jing; Chen, Hui; Wang, Yude; Guan, Hongtao; Xiao, Xuechun

    2012-12-01

    Structural, optical, and electronic properties of a new alkali metal-rare earth polyphosphate, RbHo(PO3)4, have been investigated by means of single-crystal X-ray diffraction, power X-ray diffraction, elemental analysis, and spectral measurement. RbHo(PO3)4 crystallizes in the monoclinic with space group P21/n and Z = 4. It is described as a three-dimensional (3D) architecture built up of PO4 double spiral chains and HoO8 polyhedra by corner-sharing. The 11-coordinated rubidium atoms are located in infinite tunnels. Additionally, in order to gain further insight into the relationship between property and structure of RbHo(PO3)4, theoretical calculation based on the density functional theory (DFT) was performed using the total-energy code CASTEP.

  1. Decrease in collectivity at high spins in 79Rb nucleus

    International Nuclear Information System (INIS)

    Sinha, Rishi Kumar; Dhal, Anukul; Chaturvedi, L.; Agarwal, Priyanka; Suresh Kumar; Jain, A.K.; Monika; Thind, K.S.; Bikram Singh, Bir; Rajesh Kumar; Govil, I.M.; Bringel, P.; Neusser, A.; Rakesh Kumar; Golda, K.S.; Singh, R.P.; Muralithar, S.; Madhvan, N.; Das, J.J.; Bhowmik, R.K.; Sinha, A.K.; Pancholi, S.C.; Joshi, P.K.

    2004-01-01

    The life time for the +ve and -ve parity πg 9/2 πp 3/2 bands in 79 Rb were measured by the Doppler Shift Attenuation Methods (DSAM) to investigate nuclear collectivity as a function of rotational frequency

  2. Systems of Rb2I2-CdI2-PbI2 and Cs2I2-CdI2-PbI2

    International Nuclear Information System (INIS)

    Volchanskaya, V.V.; Il'yasov, I.I.

    1979-01-01

    The Rb 2 I 2 -CdI 2 -PbI 2 and Cs 2 I 2 -CdI 2 -PbI 2 triple systems have been studied, using the visual-polythermal method. The liquidus of the systems researched consists of the components and compounds crystallization fields: 2RbIxCdI 2 , 2RbIxRbI 2 , RbIxPbI 2 and 2CsIxCdI 2 , 4CsIxPbI 2 , CsIxPbI 2 , respectively. The crystallization fields converge in four non-variant points at 360, 280, 205 and 192 deg C in the Rb 2 I 2 -CdI 2 -PbI 2 system and at 375, 368, 208 and 190 deg C in the CsI 2 -CdI 2 -PbI 2 system

  3. Preliminary measurements of the 87Rb half-life by means of the needle counter

    International Nuclear Information System (INIS)

    Zastawny, A.; Rabsztyn, B.

    1989-01-01

    In order to test the detector and to obtain the experience before starting the exact measurements, the measurements of 87 Rb half-life have been made. RbNO 3 produced by Merck was used to prepare the samples. The samples were prepared by evaporation of RbNO 3 water solution on an aluminium foil of 2,9 mg/cm 2 . The water solutions were changed in the range from (3286,4±1,8) x 10 -6 to (480,85±0,3) x 10 -6 . The background of the aluminium foil was equal to (0,117±0,007) cpm. In other measurements the back-scattering effect of 87 Rb beta rays on the aluminium foil amounted to 4%, as the measurements were performed in the 2π geometry. The diameters of samples were about 10 mm. The specific radioactivities of samples were measured versus the surface changed in the range (60-320) μg/cm 2 . The extrapolated value of the half-life, corrected for the chemical purity of the compound (as declared by the manufacterer) is equal to (4,86±0,1) x 10 10 years. This value is in good agreement with commonly accepted value of 4,88 x 10 10 years and with another last measurements. 10 refs., 1 fig., 2 tabs. (author)

  4. Synthesis and properties of Rb2GeF6:Mn4+ red-emitting phosphors

    Science.gov (United States)

    Sakurai, Shono; Nakamura, Toshihiro; Adachi, Sadao

    2018-02-01

    Rb2GeF6:Mn4+ red-emitting phosphors were synthesized by coprecipitation and their structural and optical properties were investigated by laser microscopy observation, X-ray diffraction (XRD) analysis, photoluminescence (PL) analysis, PL excitation (PLE) spectroscopy, and PL decay measurement. Single-crystalline ingots in the form of a hexagonal pyramid were prepared with a basal plane diameter of ˜2 mm. The XRD analysis suggested that Rb2GeF6 crystallizes in the hexagonal structure (C6v4 = P63mc) with a = 0.5955 nm and c = 0.9672 nm. The phosphor exhibited the strong Mn4+-related zero-phonon line (ZPL) emission peak typically observed in host crystals with piezoelectrically active lattices such as a hexagonal lattice. The quantum efficiencies of the bulk ingot and powdered samples were 87 and 74%, respectively, with nearly the same luminescence decay time of ˜6 ms. The exact ZPL energies and related crystal-field and Racah parameters were obtained from the PL and PLE spectra by Franck-Condon analysis. Temperature-dependent PL intensities were analyzed from T = 20 to 500 K using a thermal quenching model by considering Bose-Einstein phonon statistics. A comparative discussion on the phosphor properties of Rb2GeF6:Mn4+ and Rb2MF6:Mn4+ with M = Si and Ti was also given.

  5. Quantitative analysis of coronary endothelial function with generator-produced {sup 82}Rb PET: comparison with {sup 15}O-labelled water PET

    Energy Technology Data Exchange (ETDEWEB)

    Yoshinaga, Keiichiro [Hokkaido University Graduate School of Medicine, Department of Photobiology, Division of Molecular/Cellular Imaging, Kita-Ku, Sapporo, Hokkaido (Japan); Manabe, Osamu; Tamaki, Nagara [Hokkaido University of Graduate School of Medicine, Department of Nuclear Medicine, Sapporo (Japan); Katoh, Chietsugu [Hokkaido University of Graduate School of Medicine, Department of Health Sciences, Sapporo (Japan); Chen, Li; Kemp, Robert A. de; Williams, Kathryn; Beanlands, Rob S.B. [University of Ottawa Heart Institute, National Cardiac PET Centre, Division of Cardiology, Ottawa, Ontario (Canada); Klein, Ran [Hokkaido University of Graduate School of Medicine, Department of Nuclear Medicine, Sapporo (Japan); University of Ottawa Heart Institute, National Cardiac PET Centre, Division of Cardiology, Ottawa, Ontario (Canada); Naya, Masanao [Hokkaido University of Graduate School of Medicine, Department of Cardiology, Sapporo (Japan)

    2010-12-15

    Endothelial dysfunction is the earliest abnormality in the development of coronary atherosclerosis. {sup 82}Rb is a generator-produced positron emission tomography (PET) myocardial perfusion tracer that is becoming more widely used. We aimed to (1) develop a method for quantitative assessment of coronary endothelial function using the myocardial blood flow (MBF) response during a cold pressor test (CPT) in smokers, measured using {sup 82}Rb PET, and (2) compare the results with those measured using {sup 15}O-water PET. MBF was assessed at rest and during the CPT with {sup 82}Rb and {sup 15}O-water in nine controls and ten smokers. A one-compartment model with tracer extraction correction was used to estimate MBF with both tracers. CPT response was calculated as the ratio of MBF during the CPT to MBF at rest. At rest, measurements of MBF for smokers vs controls were not different using {sup 15}O-water (0.86 {+-} 0.18 vs 0.70 {+-} 0.13, p = 0.426) than they were using {sup 82}Rb (0.83 {+-} 0.23 vs 0.62 {+-} 0.20, p = 0.051). Both methods showed a reduced CPT response in smokers vs controls ({sup 15}O-water, 1.03 {+-} 0.21 vs 1.42 {+-} 0.29, p = 0.006; {sup 82}Rb, 1.02 {+-} 0.28 vs 1.70 {+-} 0.52, p < 0.001). There was high reliability [intraclass correlation coefficients: 0.48 (0.07, 0.75)] of MBF measurement between {sup 82}Rb and {sup 15}O-water during the CPT. Using a CPT, {sup 82}Rb MBF measurements detected coronary endothelial dysfunctions in smokers. {sup 82}Rb MBF measurements were comparable to those made using the {sup 15}O-water approach. Thus, {sup 82}Rb PET may be applicable for risk assessments or evaluation of risk factor modification in subjects with coronary risk factors. (orig.)

  6. A study on criticality of coupled fast-thermal core HERBE at RB reactor

    Energy Technology Data Exchange (ETDEWEB)

    Pesic, M; Zavaljevski, M; Milosevic, M; Stefanovic, D; Nikolic, D; Avdic, S [Boris Kidric Institute of Nuclear Sciences, Vinca, Belgrade (Yugoslavia); Popovic, D; Marinkovic, P [Faculty of Electrical Engineering, Beograd (Yugoslavia)

    1991-07-01

    The coupled fast-thermal core HERBE at the RB zero power heavy water reactor in Vinca was designed with the aim of improving the experimental possibilities in fast neutron fields. The requirements for minimum modifications in the RB construction and the use available fuel, restricted design flexibility of the coupled system. The following core is considered optimal in the light of the foregoing constraints: the central fast core of natural uranium is surrounded by a neutron filter zone (cadmium and natural uranium) and a converter zone (enriched uranium fuel, without moderator). The coupling region is heavy water. The thermal core in the form of the RB heavy water 80% enriched uranium lattice with 12 cm pitch. The criticality of the system is obtained by adjusting the moderator level. The critical heavy water levels were measured for normal reactor operation and some simulated accidental conditions. These data were analyzed by a computer code for the design of thermal and coupled fast-thermal reactor recently developed in IBK Nuclear Engineering Laboratory. Good agreement between the computations and experimental data was achieved. (author)

  7. A study on criticality of coupled fast-thermal core HERBE at RB reactor

    International Nuclear Information System (INIS)

    Pesic, M.; Zavaljevski, M.; Milosevic, M.; Stefanovic, D.; Nikolic, D.; Avdic, S.; Popovic, D.; Marinkovic, P.

    1991-01-01

    The coupled fast-thermal core HERBE at the RB zero power heavy water reactor in Vinca was designed with the aim of improving the experimental possibilities in fast neutron fields. The requirements for minimum modifications in the RB construction and the use available fuel, restricted design flexibility of the coupled system. The following core is considered optimal in the light of the foregoing constraints: the central fast core of natural uranium is surrounded by a neutron filter zone (cadmium and natural uranium) and a converter zone (enriched uranium fuel, without moderator). The coupling region is heavy water. The thermal core in the form of the RB heavy water 80% enriched uranium lattice with 12 cm pitch. The criticality of the system is obtained by adjusting the moderator level. The critical heavy water levels were measured for normal reactor operation and some simulated accidental conditions. These data were analyzed by a computer code for the design of thermal and coupled fast-thermal reactor recently developed in IBK Nuclear Engineering Laboratory. Good agreement between the computations and experimental data was achieved. (author)

  8. The Role of RB in the Therapeutic Response of Breast Cancer

    National Research Council Canada - National Science Library

    Bosco, Emily E

    2005-01-01

    The retinoblastoma tumor suppressor protein (RB) participates in the growth regulation of breast cancer cells by controlling G-S phase progression and mediating cell cycle arrest in response to anti-mitogenic signaling...

  9. Overexpression of Brucella putative glycosyltransferase WbkA in B. abortus RB51 leads to production of exopolysaccharide

    Directory of Open Access Journals (Sweden)

    Neha eDabral

    2015-06-01

    Full Text Available Brucella spp. are Gram-negative, facultative intracellular bacteria that cause brucellosis in mammals. Brucella strains containing the O-polysaccharide in their cell wall structure exhibit a smooth phenotype whereas the strains devoid of the polysaccharide show rough phenotype. B. abortus strain RB51 is a stable rough attenuated mutant which is used as a licensed live vaccine for bovine brucellosis. Previous studies have shown that the wboA gene, which encodes a glycosyltransferase required for the synthesis of O-polysaccharide, is disrupted in B. abortus RB51 by an IS711 element. Although complementation of strain RB51 with a functional wboA gene results in O-polysaccharide synthesis in the cytoplasm, it does not result in smooth phenotype. The aim of this study was to determine if overexpression of Brucella WbkA or WbkE, two additional putative glycosyltransferases essential for O-polysaccharide synthesis, in strain RB51 would result in the O-polysaccharide synthesis and smooth phenotype. Our results demonstrate that overexpression of wbkA or wbkE gene in RB51 does not result in O-polysaccharide expression as shown by Western blotting with specific antibodies. However, wbkA, but not wbkE, overexpression leads to the development of a clumping phenotype and the production of exopolysaccharide(s containing mannose, galactose, N-acetylglucosamine and N-acetylgalactosamine. Moreover, we found that the clumping recombinant strain displays increased adhesion to polystyrene plates. The recombinant strain was similar to strain RB51 in its attenuation characteristic and in its ability to induce protective immunity against virulent B. abortus challenge in mice.

  10. First-principles study of half-metallic properties in RbCaNZ (Z = O, S, and Se) quaternary Heusler compounds

    Science.gov (United States)

    Rezaei, S.; Ahmadian, F.

    2018-06-01

    On the basis of first principles calculations, the electronic structures and magnetic properties of quaternary Heusler alloys RbCaNZ (Z = O, S, and Se) were studied. The negative formation energies indicated that all these compounds were thermodynamically stable and thus may be experimentally synthesized at appropriate conditions in the future. The results showed that YI structure was the most favorable configuration among the three possible structures. All compounds were found to be half-metallic ferromagnets. The characteristic of energy bands and origin of half-metallicity were also verified. The total magnetic moments of RbCaNZ (Z = O, S, and Se) compounds were obtained 2μB per formula unit, which were in an agreement with Slater-Pauling rule (Mtot = 12 - Ztot). Half-metallicity was preserved at ranges of 5.06-8.36 Å, 5.96-8.81 Å, and 6.13-8.73 Å for RbCaNO, RbCaNS, and RbCaNSe compounds, respectively, which show that these quaternary Heusler compounds may be potential candidates in spintronic applications.

  11. Ternary rare-earth halides of the A2MX5 type (A = K, In, NH4, Rb, Cs; X = Cl, Br, I)

    International Nuclear Information System (INIS)

    Meyer, G.; Soose, J.; Moritz, A.; Vitt, V.; Holljes, T.

    1985-01-01

    Ternary rare-earth (=M) chlorides, bromides, and iodides In 2 MCl 5 , (NH 4 ) 2 MCl 5 , Rb 2 MCl 5 , Cs 2 MCl 5 , CsRbMCl 5 , K 2 MBr 5 , Rb 2 MBr 5 , K 2 MI 5 , and Rb 2 MI 5 have been synthesized. Single crystals of In 2 PrCl 5 , Rb 2 PrCl 5 , K 2 PrBr 5 , and K 2 PrI 5 were grown and the structures refined. The other halides were characterized by X-ray powder patterns. They are isotypic either with K 2 PrCl 5 (orthorhombic, Pnma, Z = 4, hexagonal arrangement of chains of edge-connected polyhedra [PrX 7 ]) or with Cs 2 DyCl 5 (orthorhombic, Pbnm, Z = 4, hexagonal arrangement of cis-corner-connected octahedra [DyCl 6 ]) which may be discriminated in structure field diagrams. The thermal expansion was investigated for Cs 2 LuCl 5 and Rb 2 PrX 5 (X = Cl, Br, I). (author)

  12. Syntheses, crystal structure, and electronic properties of the five ABaMQ{sub 4} compounds RbBaPS{sub 4}, CsBaPS{sub 4}, CsBaVS{sub 4}, RbBaVSe{sub 4}, and CsBaVSe{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Mesbah, Adel [Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113 (United States); ICSM, UMR 5257 CEA / CNRS / UM / ENSCM, Site de Marcoule-Bâtiment 426, BP 17171, 30207 Bagnols-sur-Cèze Cedex (France); Prakash, Jai [Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113 (United States); Rocca, Dario; Lebègue, Sébastien [Laboratoire de Cristallographie, Résonance Magnétique, et Modélisations CRM2 (UMR UHP-CNRS 7036), Faculté des Sciences et Techniques, Université de Lorraine, BP 70239, Boulevard des Aiguillettes, 54506 Vandoeuvre-lès-Nancy Cedex (France); Beard, Jessica C.; Lewis, Benjamin A. [Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113 (United States); Ibers, James A., E-mail: ibers@chem.northwestern.edu [Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113 (United States)

    2016-01-15

    Five new compounds belonging to the ABaMQ{sub 4} family were synthesized by solid-state chemistry at 1123 K. The compounds RbBaPS{sub 4}, CsBaPS{sub 4}, CsBaVS{sub 4}, RbBaVSe{sub 4}, and CsBaVSe{sub 4} are isostructural and have the TlEuPS{sub 4} structure type. They crystallize in space group D{sup 16}{sub 2h} – Pnma of the orthorhombic system. Their structure consists isolated MQ{sub 4} tetrahedra separated by A and Ba atoms to form a salt-like structure. Density Functional Theory (DFT) calculations of the electronic structures with the use of the HSE functional suggest that the compounds are semiconductors with calculated band gaps of 3.3 eV (RbBaPS{sub 4}), 3.4 eV (CsBaPS{sub 4}), 2.3 eV (CsBaVS{sub 4}), and 1.6 eV (RbBaVSe{sub 4}). - Graphical abstract: General view of the ABaMQ{sub 4} structure down the a axis. - Highlights: • Five new ABaMQ{sub 4} compounds were synthesized by solid-state chemistry at 1123 K. • RbBaPS{sub 4}, CsBaPS{sub 4}, CsBaVS{sub 4}, RbBaVSe{sub 4}, and CsBaVSe{sub 4} have the TlEuPS{sub 4} structure type. • The compounds are semiconductors with calculated band gaps ranging from 1.6 to 3.4 eV.

  13. MDM2, p53 and pRb Expression Prior to Definitive Chemoradiotherapy in Esophageal Carcinoma

    International Nuclear Information System (INIS)

    Yoon, Mee Sun; Nam, Taek Keun; Lee, Jae Hyuk; Cho, Sang Hee; Song, Ju Young; Ahn, Sung Ja; Chung, Ik Joo; Chung, Woong Ki; Nah, Byung Sik

    2007-01-01

    Purpose: This study evaluated the pretreatment expression patterns of MDM2, p53, and pRb proteins to determine if the expression patterns could predict the outcome of concurrent chemoradiotherapy (CCRT) for esophageal squamous cell carcinoma and aid in the decisions for the selection of treatment modalities. Materials and Methods: Fifty-one patients that were treated with definitive hemoradiotherapy for stage I∼ IVa esohageal squamous cell carcinoma were selected for this study. Radiotherapy was administered with daily 1.8∼2 Gy fractions up to a median dose of 54 Gy for primary tumors, and with four cycles of cisplatin/5-fluorouracil chemotherapy that was administered every 4 weeks, the first two cycles of which were administered concurrently with radiotherapy. Expression of MDM2, p53, and pRb was investigated by immunohistochemical analysis using pretreatment biopsy specimens. Results: MDM2, p53, and pRb were detected with high immunoreactivity in 19.6%, 27.5%, and 66.7% of the patients, respectively. However, there was no significant correlation between expression of these factors and clinical outcome. By the use of multivariate analysis with nine covariates-age, tumor location, tumor length, stage, pathological response, clinical response, MDM2 expression, p53 expression, and pRb expression, only pathological response and stage were significant factors for cause-specific survival. Conclusion: Expression of MDM2, p53, and pRb was not found to be clinically significant for predicting outcomes after CCRT in this study. Further studies with a larger patient population and longer follow-up periods are needed to re-evaluate the expression pattern and to identify new predictors for CCRT response

  14. Synthesis and Characterization of the Ternary Thiobismuthates A9Bi13S24 (A = K, Rb)

    KAUST Repository

    Davaasuren, Bambar; Alahmary, Fatimah S.; Dashjav, Enkhtsetseg; Khanderi, Jayaprakash; Rothenberger, Alexander

    2016-01-01

    .9072(9) Å, β = 105.826(3)° for KBiS (1) and a = 31.823(6) Å, b = 4.1177(8) Å, c = 21.086(4) Å, β = 105.62(3)° for RbBiS (2). The crystal structure of 1 contains a 3D [KBiS] polyanionic framework, whereas 2 consists of 2D [RbBiS] polyanionic slabs stacked

  15. Musa's granite and Rio Maria's granodiorite Rb/Sr isotopic ages and geochemistry

    International Nuclear Information System (INIS)

    Gastal, M.C.P.; Macambira, M.J.B.; Medeiros, H.; Dall'Agnol, R.

    1987-01-01

    The Musa Granite and the Rio Maria Granodiorite are located at the eastern margin of the Amazonian craton, in the Rio Maria region, where a typical granite-greenstone terrain is characterized. Rb-Sr dating of six samples from different facies of Rio Maria Granodiorite furnished an age of 2564 ± 68 Ma with initial 87 Sr/ 86 Sr radio (IR) of 0.70288 ± 0.00092 (whole rock isochron; 1 ο error; MSWD = 2.26). Thirteen samples from the three facies of Musa Granite (monzogranites, syenogranites and intermediate to felsic hypabyssal rocks) gave Rb-Sr whole rock isochron with an age of 1692 ± 11 Ma and IR of 0.70777 ± 0.00023 (1 ο error, MSWD = 1.89). A preliminary attempt to individualize geochronologically the three facies was done resulting different ages and IRs. There is a coincidence between these ages and the emplacement sequence of these facies of the pluton. The actual meaning of the Rio Maria Granodiorite Rb-Sr age is still uncertain. It could be related to the end of the magmatic crystallization of the batholith as well as to the metamorphic-mylonitic event that affect it. Considering that the Jamon and Musa Granites are petrologically similar that they occur in the same area, it is interesting to note that latter is apparently a little older than the former. The IRs obtained for the two plutons are also not coincident. The isotopic Rb-Sr available data show that the exposed rocks of the Rio Maria Granodiorite have not been able to generate magmas with the compositions of the monzongranitic and the hypabyssal facies of the Musa pluton. On the other hand, rocks isotopically similar to the Rio Maria Granodiorite would theorically be able to generate the Jamon and a magma with the characteristics of the syenogranitic facies of the Musa pluton. (author) [pt

  16. Bonding in Mercury-Alkali Molecules: Orbital-driven van der Waals Complexes

    Directory of Open Access Journals (Sweden)

    Dieter Cremer

    2008-06-01

    Full Text Available The bonding situation in mercury-alkali diatomics HgA (2Σ+ (A = Li, Na, K, Rb has been investigated employing the relativistic all-electron method Normalized Elimination of the Small Component (NESC, CCSD(T, and augmented VTZ basis sets. Although Hg,A interactions are typical of van der Waals complexes, trends in calculated De values can be explained on the basis of a 3-electron 2-orbital model utilizing calculated ionization potentials and the De values of HgA+(1Σ+ diatomics. HgA molecules are identified as orbital-driven van der Waals complexes. The relevance of results for the understanding of the properties of liquid alkali metal amalgams is discussed.

  17. Comparative modeling and docking studies of p16ink4/Cyclin D1/Rb pathway genes in lung cancer revealed functionally interactive residue of RB1 and its functional partner E2F1

    Directory of Open Access Journals (Sweden)

    e Zahra Syeda Naqsh

    2013-01-01

    Full Text Available Abstract Background Lung cancer is the major cause of mortality worldwide. Major signalling pathways that could play significant role in lung cancer therapy include (1 Growth promoting pathways (Epidermal Growth Factor Receptor/Ras/ PhosphatidylInositol 3-Kinase (2 Growth inhibitory pathways (p53/Rb/P14ARF, STK11 (3 Apoptotic pathways (Bcl-2/Bax/Fas/FasL. Insilico strategy was implemented to solve the mystery behind selected lung cancer pathway by applying comparative modeling and molecular docking studies. Results YASARA [v 12.4.1] was utilized to predict structural models of P16-INK4 and RB1 genes using template 4ELJ-A and 1MX6-B respectively. WHAT CHECK evaluation tool demonstrated overall quality of predicted P16-INK4 and RB1 with Z-score of −0.132 and −0.007 respectively which showed a strong indication of reliable structure prediction. Protein-protein interactions were explored by utilizing STRING server, illustrated that CDK4 and E2F1 showed strong interaction with P16-INK4 and RB1 based on confidence score of 0.999 and 0.999 respectively. In order to facilitate a comprehensive understanding of the complex interactions between candidate genes with their functional interactors, GRAMM-X server was used. Protein-protein docking investigation of P16-INK4 revealed four ionic bonds illustrating Arg47, Arg80,Cys72 and Met1 residues as actively participating in interactions with CDK4 while docking results of RB1 showed four hydrogen bonds involving Glu864, Ser567, Asp36 and Arg861 residues which interact strongly with its respective functional interactor E2F1. Conclusion This research may provide a basis for understanding biological insights of P16-INK4 and RB1 proteins which will be helpful in future to design a suitable drug to inhibit the disease pathogenesis as we have determined the interacting amino acids which can be targeted in order to design a ligand in-vitro to propose a drug for clinical trials. Protein -protein docking of

  18. Emerging differential roles of the pRb tumor suppressor in trichodysplasia spinulosa-associated polyomavirus and Merkel cell polyomavirus pathogeneses.

    Science.gov (United States)

    Wu, Julie H; Simonette, Rebecca A; Nguyen, Harrison P; Doan, Hung Q; Rady, Peter L; Tyring, Stephen K

    2016-03-01

    Merkel cell carcinoma (MCC) and trichodysplasia spinulosa (TS) are two proliferative cutaneous diseases caused by the Merkel cell polyomavirus (MCPyV) and trichodysplasia spinulosa-associated polyomavirus (TSPyV) respectively. Recently, studies have elucidated a key role of the small tumor (sT) antigen in the proliferative pathogenic mechanisms of MCPyV and likely TSPyV. While both sT antigens have demonstrated a capacity in regulating cellular pathways, it remains unknown whether MCPyV and TSPyV sT antigens contribute similarly or differentially to cell proliferation. The present study aims to explore the proliferative potential of MCPyV and TSPyV sT antigens by investigating their regulatory effects on the retinoblastoma protein (pRb) tumor suppressor. Inducible cell lines expressing MCPyV sT or TSPyV sT were created using a lentiviral packaging system. Cellular proteins were extracted and subjected to SDS-PAGE followed by Western blot detection and densitometric analysis. Expression of TSPyV sT markedly enhanced the phosphorylation of pRb in Western blot experiments. In contrast, expression of MCPyV sT did not alter pRb phosphorylation under the same experimental conditions. Densitometric analysis revealed that TSPyV sT antigen expression nearly doubled the ratio of phosphorylated to total pRb (P<0.001, Student's T-test), while MCPyV sT antigen expression did not cause significant change in pRb phosphorylation status. Given that hyperphosphorylation of pRb is associated with dysregulation of the cell cycle, S-phase induction, and increased cell proliferation, our findings support an important role of TSPyV-mediated pRb deactivation in the development of TS. The observation that the pRb tumor suppressor is inactivated by TSPyV sT but not MCPyV sT provides further insights into the distinct pathobiological mechanisms of MCC and TS. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. RB research reactor safety report; Izvestaj o sigurnsti istrazivackog reaktora RB

    Energy Technology Data Exchange (ETDEWEB)

    Sotic, O; Pesic, M; Vranic, S [Boris Kidric Institute of Nuclear Sciences Vinca, Beograd (Yugoslavia)

    1979-04-15

    This new version of the safety report is a revision of the safety report written in 1962 when the RB reactor started operation after reconstruction. The new safety report was needed because reactor systems and components have been improved and the administrative procedures were changed. the most important improvements and changes were concerned with the use of highly enriched fuel (80% enriched), construction of reactor converter outside the reactor vessel, improved control system by two measuring start-up channels, construction of system for heavy water leak detection, new inter phone connection between control room and other reactor rooms. This report includes description of reactor building with installations, rector vessel, reactor core, heavy water system, control system, safety system, dosimetry and alarm systems, experimental channels, neutron converter, reactor operation. Safety aspects contain analyses of accident reasons, method for preventing reactivity insertions, analyses of maximum hypothetical accidents for cores with natural uranium, 2% enriched and 80% enriched fuel elements. Influence of seismic events on the reactor safety and well as coupling between reactor and the converter are parts of this document.

  20. Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFβ cell cycle arrest

    Directory of Open Access Journals (Sweden)

    Harrison David J

    2007-11-01

    Full Text Available Abstract Background TGFβ is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity. The retinoblastoma protein pRb is a key controller of E2F activity and G1/S transition which can be inhibited in viral hepatitis. It is not known whether the impairment of pRb would alter the growth inhibitory potential of TGFβ in disease. We asked how Rb-deficiency would affect responses to TGFβ-induced cell cycle arrest. Results Primary hepatocytes isolated from Rb-floxed mice were infected with an adenovirus expressing CRE-recombinase to delete the Rb gene. In control cells treatment with TGFβ prevented cells to enter S phase via decreased cMYC activity, activation of P16INK4A and P21Cip and reduction of E2F activity. In Rb-null hepatocytes, cMYC activity decreased slightly but P16INK4A was not activated and the great majority of cells continued cycling. Rb is therefore central to TGFβ-induced cell cycle arrest in hepatocytes. However some Rb-null hepatocytes remained sensitive to TGFβ-induced cell cycle arrest. As these hepatocytes expressed very high levels of P21Cip1 and P53 we investigated whether these proteins regulate pRb-independent signaling to cell cycle arrest by evaluating the consequences of disruption of p53 and p21Cip1. Hepatocytes deficient in p53 or p21Cip1 showed diminished growth inhibition by TGFβ. Double deficiency had a similar impact showing that in cells containing functional pRb; P21Cip and P53 work through the same pathway to regulate G1/S in response to TGFβ. In Rb-deficient cells however, p53 but not p21Cip deficiency had an additive effect highlighting a pRb-independent-P53-dependent effector pathway of inhibition of E2F activity. Conclusion The present results show that otherwise genetically normal hepatocytes with disabled p53, p21Cip1 or Rb genes respond less well to the antiproliferative effects of TGFβ. As the function of

  1. RB1 mutations and second primary malignancies after hereditary retinoblastoma

    NARCIS (Netherlands)

    Dommering, Charlotte J.; Marees, Tamara; van der Hout, Annemarie H.; Imhof, Saskia M.; Meijers-Heijboer, Hanne; Ringens, Peter J.; van Leeuwen, Flora E.; Moll, Annette C.

    2012-01-01

    Survivors of hereditary retinoblastoma have a high risk of second primary malignancies, but it has not been investigated whether specific RB1 germline mutations are associated with greater risk of second primary malignancies in a large cohort. We conducted a retrospective cohort study of 199

  2. RB1 mutations and second primary malignancies after hereditary retinoblastoma

    NARCIS (Netherlands)

    Dommering, Charlotte J.; Marees, Tamara; van der Hout, Annemarie H.; Imhof, Saskia M.; Meijers-Heijboer, Hanne; Ringens, Peter J.; van Leeuwen, Flora E.; Moll, Annette C.

    Survivors of hereditary retinoblastoma have a high risk of second primary malignancies, but it has not been investigated whether specific RB1 germline mutations are associated with greater risk of second primary malignancies in a large cohort. We conducted a retrospective cohort study of 199

  3. Antiferromagnetic CsCrF{sub 5} and canted antiferromagnetism in RbCrF{sub 5} and KCrF{sub 5}

    Energy Technology Data Exchange (ETDEWEB)

    Jagličić, Zvonko, E-mail: zvonko.jaglicic@imfm.si [University of Ljubljana, Faculty of Civil and Geodetic Engineering, and Institute of Mathematics, Physics and Mechanics, Jadranska 19, 1000 Ljubljana (Slovenia); Mazej, Zoran, E-mail: zoran.mazej@ijs.si [Department of Inorganic Chemistry and Technology, Jožef Stefan Institute, Jamova 39, 1000 Ljubljana (Slovenia)

    2017-07-15

    Highlights: • Cr(IV) ions are antiferromagnetically coupled within chains in ACrF{sub 5} (A = Cs, Rb, K). • Small structural difference causes huge difference in magnetic properties below 10 K. • Canted antiferromagnetism has been observed in RbCrF{sub 5} and KCrF{sub 5} at low temperature. - Abstract: In ACrF{sub 5} (A = Cs, Rb, K), Cr(IV) ions are coordinated by six fluoride ligands where the resulting CrF{sub 6} octahedra share cis vertexes to form infinite chains of ([Cr{sup IV}F{sub 5}]{sup −}){sub n}. The geometry of the latter in Cs compound differs from that in K and Rb compounds. The results of investigations of the magnetic behaviour of these compounds have shown that an antiferromagnetic superexchange interaction is present within the chains with J{sub Cs} = −10.2 cm{sup −1}, J{sub Rb} = −13.3 cm{sup −1}, and J{sub K} = −13.1 cm{sup −1}. Additional ferromagnetic-like long-range ordering has been observed in KCrF{sub 5} and RbCrF{sub 5} below 6 K which can be explained, in a correlation with their crystal structures, as canted antiferromagnetism.

  4. First principles study of structural, electronic and optical properties of polymorphic forms of Rb 2Te

    Science.gov (United States)

    Alay-e-Abbas, S. M.; Shaukat, A.

    2011-05-01

    First-principles density functional theory calculations have been performed for structural, electronic and optical properties of three polymorphic forms of rubidium telluride. Our calculations show that the sequence of pressure induced phase transitions for Rb 2Te is Fm3¯m → Pnma → P6 3/mmc which is governed by the coordination numbers of the anions. From our calculated low transition pressure value for the Fm3¯m phase to the Pnma phase transition of Rb 2Te, the experimentally observed meta-stability of Fm3¯m phase at ambient conditions seems reasonable. The electronic band structure has been calculated for all the three phases and the change in the energy band gap is discussed for the transitioning phases. The energy band gaps obtained for the three phases of Rb 2Te decrease on going from the meta-stable phase to the high-pressure phases. Total and partial density of states for the polymorphs of Rb 2Te has been computed to elucidate the contribution of various atomic states on the electronic band structure. Furthermore, optical properties for all the polymorphic forms have been presented in form of the complex dielectric function.

  5. Solvent effect on Rb+ to K+ ion mutation: Monte Carlo simulation study

    International Nuclear Information System (INIS)

    Kim, Hag Sung

    2000-01-01

    The solvent effects on the relative free energies of solvation and the difference in partition coefficients (log P) for Rb + to K + mutation in several solvents have been investigated using Monte Carlo simulation (MCS) of statistical perturbation theory (SPT). In comparing the relative free energies for interconversion of one ion pair, Rb + to K + , in H 2 O (TIP4P) in this study with the relative free energies of the computer simulations and the experimental, we found that the figure in this study is -5.00 ± 0.11 kcal/mol. There is good agreement among various studies, taking into account both methods used to obtain the hydration free energies and standard deviations. There is also good agreement between the calculated structural properties of this study and the simulations, ab initio and the experimental results. We have explained the deviation of the relationship between the free energy difference and the Onsager dielectric function of solvents by the electron pair donor properties of the solvents. For the Rb + and K + ion pair, the Onsager dielectric function of solvents (or solvent permittivity), donor number of solvent and the differences in solvation dominate the differences in the relative free energies of solvation and partition coefficients

  6. Kinetic parameters of the RB and RA reactors

    Energy Technology Data Exchange (ETDEWEB)

    Petrovic, M; Obradovic, D [Institute of nuclear sciences Boris Kidric, Vinca, Beograd (Yugoslavia)

    1965-12-15

    In the paper the expressions for transfer functions of the zero power reactors, as well as power reactors of the RA reactor type are given, based on the space independent model. The modulation method for reactor transfer function measurements is explained. The results of the measurement and interpretation are given. The measurement were done on the RB and RA reactors in 'Boris Kidrich' Institute for Nuclear Sciences in Vincha (author)

  7. Geological, Geochemical 1 and Rb-Sr isotopic studies on tungsten 2 ...

    Indian Academy of Sciences (India)

    37

    Geological, Geochemical and Rb-Sr isotopic studies on tungsten. 1 mineralised ..... From the field relations it is demonstrated that SG (biotite-bearing granitic gneiss) and. 120 ..... cases Ba) and vice-versa for the low concentration. 291.

  8. Relative Renal Blood Flow Measurements With Rb-82 and a Hybrid Gamma Camera Using a Pig Model

    Science.gov (United States)

    Pretorius, P. H.; Fung, L. C. T.; Schell, C. P.; King, M. A.

    2005-02-01

    We have successfully demonstrated with chronically implanted blood flow probes in a pig model that renal uptake of Rb-82 is indeed sensitive to acute renal blood flow changes. Two flow probes were placed around the left and right renal arteries in a surgical procedure nine weeks before the first Rb-82 measurements. Together with the flow probes, a flow restrictor was implanted around the left renal artery. Single bolus infusions of 6 mCi Rb-82 were used to study the uptake in the kidneys approximately 7 minutes apart in hybrid-image limited-angle acquisitions (stationary camera heads posterior and anterior of the pig) while changing the flow to the left kidney between acquisitions. The acquired data were reconstructed into 7.5-s frames using a maximum likelihood (ML) list-mode reconstruction algorithm exploiting timing signals inserted into the list every 0.25 s. Reconstructed data were orientated to coronal views before regions of interest (ROIs) were drawn over both kidneys with a separate background region for each. The data represented are noisy due to the reconstructed 7.5-s frames, and the total imaging time of 5 min (or 4 Rb-82 half-lives). We were able to show a steady decline in uptake of Rb-82 in the left kidney that correlates with the reduction in renal blood flow. The reduced blood flow to the left kidney affects the Rb-82 uptake to the right kidney slightly, while blood flow decreased up to 33%. Comparing the baseline renal blood flow of the left kidney obtained before and after the intervention indicates that some ischemia persists after blood flow was restored. Attenuation compensation better described the contour of the kidney but only scales the time activity curve without changing its shape.

  9. New start-up channels and multichannel analyzer at the RB reactor; Novi start-up kanali i videkanalni analizator na reaktoru Rb

    Energy Technology Data Exchange (ETDEWEB)

    Sotic, O; Markovic, H; Vranic, S; Dimitrijevic, Z; Pesic, M [Boris Kidric Institute of Nuclear Sciences Vinca, Beograd (Yugoslavia)

    1978-01-15

    New start-up channels and a multichannel analyzer were purchased in 1977 for the RB reactor. Both start-up channels contain BF{sub 3} neutron detectors, preamplifier, amplifier, single-channel analyzer, scaler, ratemeter, control unit, recording instrument. This document contains detailed technical description of these devices as well as characteristics of the multichannel analyzer which is being tested and will be used for measuring irradiation in the vicinity of the reactor.

  10. Inoculation of Pichia kudriavzevii RB1 degrades the organic acids present in raw compost material and accelerates composting.

    Science.gov (United States)

    Nakasaki, Kiyohiko; Araya, Shogo; Mimoto, Hiroshi

    2013-09-01

    In this study, the yeast strain Pichia kudriavzevii RB1 was used as an inoculum to accelerate organic matter degradation of rabbit food with added organic acids, which was used as a model food waste for composting. The RB1 strain rapidly degraded the organic acids present in the raw compost material, leading to an increase in pH beyond the neutral level, within 2 days. Both mesophilic and thermophilic bacteria proliferated faster in the compost with RB1 inoculation than in that without inoculation. Although the yeast died with the increase in compost temperature, it affected the early stages of composting prior to the thermophilic stage and accelerated the composting process by 2 days by eliminating the initial lag phase seen in the growth of other microorganisms. Moreover, populations of Bacillus thermoamylovorans, Bacillus foraminis, and Bacillus coagulans became dominant during the thermophilic stages of both composting with and without RB1 inoculation. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Mutation spectrum of RB1 mutations in retinoblastoma cases from Singapore with implications for genetic management and counselling.

    Directory of Open Access Journals (Sweden)

    Swati Tomar

    Full Text Available Retinoblastoma (RB is a rare childhood malignant disorder caused by the biallelic inactivation of RB1 gene. Early diagnosis and identification of carriers of heritable RB1 mutations can improve disease outcome and management. In this study, mutational analysis was conducted on fifty-nine matched tumor and peripheral blood samples from 18 bilateral and 41 unilateral unrelated RB cases by a combinatorial approach of Multiplex Ligation-dependent Probe Amplification (MLPA assay, deletion screening, direct sequencing, copy number gene dosage analysis and methylation assays. Screening of both blood and tumor samples yielded a mutation detection rate of 94.9% (56/59 while only 42.4% (25/59 of mutations were detected if blood samples alone were analyzed. Biallelic mutations were observed in 43/59 (72.9% of tumors screened. There were 3 cases (5.1% in which no mutations could be detected and germline mutations were detected in 19.5% (8/41 of unilateral cases. A total of 61 point mutations were identified, of which 10 were novel. There was a high incidence of previously reported recurrent mutations, occurring at 38.98% (23/59 of all cases. Of interest were three cases of mosaic RB1 mutations detected in the blood from patients with unilateral retinoblastoma. Additionally, two germline mutations previously reported to be associated with low-penetrance phenotypes: missense-c.1981C>T and splice variant-c.607+1G>T, were observed in a bilateral and a unilateral proband, respectively. These findings have implications for genetic counselling and risk prediction for the affected families. This is the first published report on the spectrum of mutations in RB patients from Singapore and shows that further improved mutation screening strategies are required in order to provide a definitive molecular diagnosis for every case of RB. Our findings also underscore the importance of genetic testing in supporting individualized disease management plans for patients and

  12. Rb-Sr ages of Precambrian sediments from the Ovruch mountain range, northwestern Ukraine (U.S.S.R.)

    International Nuclear Information System (INIS)

    Gorokhov, I.M.; Varshavskaya, E.S.; Kutyavin, E.P.; Clauer, N.; Drannik, A.S.

    1981-01-01

    A mineralogical and Rb-Sr geochronological study of Precambrian sediments and metasediments from the Ovruch mountain range (northwestern Ukraine) shows two distinct events: a slight metamorphism of the Belokorovichi Formation 1575 +- 30 Ma ago which precedes the deposition of the Zbranki Formation at 1389 +- 71 Ma (lambda 87 Rb = 1.42 x 10 -11 y -1 ). (Auth.)

  13. Phospho-Rb mediating cell cycle reentry induces early apoptosis following oxygen-glucose deprivation in rat cortical neurons.

    Science.gov (United States)

    Yu, Ying; Ren, Qing-Guo; Zhang, Zhao-Hui; Zhou, Ke; Yu, Zhi-Yuan; Luo, Xiang; Wang, Wei

    2012-03-01

    The aim of this study was to investigate the relationship between cell cycle reentry and apoptosis in cultured cortical neurons following oxygen-glucose deprivation (OGD). We found that the percentage of neurons with BrdU uptake, TUNEL staining, and colocalized BrdU uptake and TUNEL staining was increased relative to control 6, 12 and 24 h after 1 h of OGD. The number of neurons with colocalized BrdU and TUNEL staining was decreased relative to the number of TUNEL-positive neurons at 24 h. The expression of phosphorylated retinoblastoma protein (phospho-Rb) was significantly increased 6, 12 and 24 h after OGD, parallel with the changes in BrdU uptake. Phospho-Rb and TUNEL staining were colocalized in neurons 6 and 12 h after OGD. This colocalization was strikingly decreased 24 h after OGD. Treatment with the cyclin-dependent kinase inhibitor roscovitine (100 μM) decreased the expression of phospho-Rb and reduced neuronal apoptosis in vitro. These results demonstrated that attempted cell cycle reentry with phosphorylation of Rb induce early apoptosis in neurons after OGD and there must be other mechanisms involved in the later stages of neuronal apoptosis besides cell cycle reentry. Phosphoralated Rb may be an important factor which closely associates aberrant cell cycle reentry with the early stages of neuronal apoptosis following ischemia/hypoxia in vitro, and pharmacological interventions for neuroprotection may be useful directed at this keypoint.

  14. The Apollo 17 'melt sheet': chemistry, age and Rb/Sr systematics

    International Nuclear Information System (INIS)

    Winzer, S.R.; Nava, D.F.; Schuhmann, S.; Philpotts, J.A.

    1977-01-01

    Major, minor and trace element compositions, age data and Rb/Sr systematics of Apollo 17 boulders have been compiled, and additional analyses performed on a norite breccia clast (77215) included in the Apollo 17, Station 7 boulder. The Apollo 17 boulders are found to be identical or nearly so in major, minor and trace element composition, suggesting that they all originated as an impact melt analogous to melt sheets found in larger terrestrial craters. The matrix dates ( 40 Ar/ 39 Ar) and Rb/Sr systematics available suggest that this impact melt formed by a single impact about 4 b.y. ago. This impact excavated, shocked, brecciated and melted norites, norite cumulates and possibly anorthositic gabbros and dunites about 4.4 b.y. old. The impact was likely a major one, possibly the Serenitatis basin-forming event. (Auth.)

  15. Operation and maintenance of the RB reactor, Annual report for 1976

    International Nuclear Information System (INIS)

    Sotic, O.; Vranic, S.

    1976-01-01

    Due to its flexibility and relatively simple construction the RB reactor enabled direct measurements of a series of physical parameters. During 1976 the reactor operation exceeded the plan due to preparation of special experiments planned for the next period. It is planned to operate the reactor at higher power levels (50 W - 10 kw). A need for increasing the neutron flux a neutron converter was built in 1976. preliminary measurements showed that placing the neutron converter next to the reactor vessel enables achievement of irradiation and dosimetry measurements in the fast neutron flux. It is planned to purchase highly enriched fuel for the neutron converter. This annual report includes 5 Annexes with data concerning: operation, irradiation field around the RB reactor, maintenance of reactor components and instrumentation, purchase of new equipment, and the program for training reactor operators

  16. Quantification of myocardial blood flow with {sup 82}Rb positron emission tomography: clinical validation with {sup 15}O-water

    Energy Technology Data Exchange (ETDEWEB)

    Prior, John O.; Allenbach, Gilles; Bischof Delaloye, Angelika [Centre Hospitalier Universitaire Vaudois and University of Lausanne, Nuclear Medicine Department, Lausanne (Switzerland); Valenta, Ines; Burger, Cyrill [Cardiac Imaging, Department of Radiology, Zurich (Switzerland); Kosinski, Marek [Centre Hospitalier Universitaire Vaudois and University of Lausanne, Nuclear Medicine Department, Lausanne (Switzerland); Centre Hospitalier Universitaire Vaudois and University of Lausanne, University Institute for Radiation Physics, Lausanne (Switzerland); Verdun, Francis R. [Centre Hospitalier Universitaire Vaudois and University of Lausanne, University Institute for Radiation Physics, Lausanne (Switzerland); Kaufmann, Philipp A. [Cardiac Imaging, Department of Radiology, Zurich (Switzerland); University of Zurich, Zurich Centre for Integrative Human Physiology (ZIHP), Zurich (Switzerland)

    2012-06-15

    Quantification of myocardial blood flow (MBF) with generator-produced {sup 82}Rb is an attractive alternative for centres without an on-site cyclotron. Our aim was to validate {sup 82}Rb-measured MBF in relation to that measured using {sup 15}O-water, as a tracer 100% of which can be extracted from the circulation even at high flow rates, in healthy control subject and patients with mild coronary artery disease (CAD). MBF was measured at rest and during adenosine-induced hyperaemia with {sup 82}Rb and {sup 15}O-water PET in 33 participants (22 control subjects, aged 30 {+-} 13 years; 11 CAD patients without transmural infarction, aged 60 {+-} 13 years). A one-tissue compartment {sup 82}Rb model with ventricular spillover correction was used. The {sup 82}Rb flow-dependent extraction rate was derived from {sup 15}O-water measurements in a subset of 11 control subjects. Myocardial flow reserve (MFR) was defined as the hyperaemic/rest MBF. Pearson's correlation r, Bland-Altman 95% limits of agreement (LoA), and Lin's concordance correlation {rho} {sub c} (measuring both precision and accuracy) were used. Over the entire MBF range (0.66-4.7 ml/min/g), concordance was excellent for MBF (r = 0.90, [{sup 82}Rb-{sup 15}O-water] mean difference {+-} SD = 0.04 {+-} 0.66 ml/min/g, LoA = -1.26 to 1.33 ml/min/g, {rho} {sub c} = 0.88) and MFR (range 1.79-5.81, r = 0.83, mean difference = 0.14 {+-} 0.58, LoA = -0.99 to 1.28, {rho} {sub c} = 0.82). Hyperaemic MBF was reduced in CAD patients compared with the subset of 11 control subjects (2.53 {+-} 0.74 vs. 3.62 {+-} 0.68 ml/min/g, p = 0.002, for {sup 15}O-water; 2.53 {+-} 1.01 vs. 3.82 {+-} 1.21 ml/min/g, p = 0.013, for {sup 82}Rb) and this was paralleled by a lower MFR (2.65 {+-} 0.62 vs. 3.79 {+-} 0.98, p = 0.004, for {sup 15}O-water; 2.85 {+-} 0.91 vs. 3.88 {+-} 0.91, p = 0.012, for {sup 82}Rb). Myocardial perfusion was homogeneous in 1,114 of 1,122 segments (99.3%) and there were no differences in MBF among the

  17. Insight into the structural, electronic, elastic and optical properties of the alkali hydride compounds, XH (X = Rb and Cs)

    Science.gov (United States)

    Jaradat, Raed; Abu-Jafar, Mohammed; Abdelraziq, Issam; Mousa, Ahmad; Ouahrani, Tarik; Khenata, Rabah

    2018-04-01

    The equilibrium structural parameters, electronic and optical properties of the alkali hydrides RbH and CsH compounds in rock-salt (RS) and cesium chloride (CsCl) structures have been studied using the full-potential linearized augmented plane-wave (FP-LAPW) method. Wu and Cohen generalized gradient approximation (WC-GGA) was used for the exchange-correlation potential to compute the equilibrium structural parameters, such as the lattice constant (a0), the bulk modulus (B) and bulk modulus first order pressure derivative (B'). In addition to the WC-GGA, the modified Becke Johnson (mBJ) scheme has been also used to overcome the underestimation of the band gap energies. RbH and CsH compounds are found to be semiconductors (wide energy-band gap) using the WC-GGA method, while they are insulators using the mBJ-GGA method. Elastic constants, mechanical and thermodynamic properties were obtained by using the IRelast package. RbH and CsH compounds at ambient pressure are mechanically stable in RS and CsCl structures; they satisfy the Born mechanical stability criteria. Elastic constants (Cij), bulk modulus (B), shear modulus (S) and Debye temperatures (θD) of RbH and CsH compounds decrease as the alkali radius increases. The RS structure of these compounds at ambient conditions is mechanically stronger than CsCl structure. RbH and CsH in RS and CsCl structures are suitable as dielectric compounds. The wide direct energy band gap for these compounds make them promising compounds for optoelectronic UV device applications. Both RbH and CsH have a wide absorption region, on the other hand RbH absorption is very huge compared to the CsH absorption, RbH is an excellent absorbent material, maximum absorption regions are located in the middle ultraviolet (MUV) region and far ultraviolet (FUV) region. The absorption coefficient α (w), imaginary part of the dielectric constant ɛ2(w) and the extinction coefficient k(w) vary in the same way. The present calculated results are in

  18. Rb-Sr age of a basic dyke, Schirmacher oasis, east Antarctica

    International Nuclear Information System (INIS)

    Dayal, A.M.; Hussain, S.M.

    1996-01-01

    In order to understand the crustal evolution in east Antartica, detailed geological, geochemical and isotopic studies of the various rocks in the area are necessary. This paper reports the Rb-Sr isotopic data on a gabbroic dyke in the Schirmacher oasis

  19. Complete genome of Pandoraea pnomenusa RB-38, an oxalotrophic bacterium isolated from municipal solid waste landfill site.

    Science.gov (United States)

    Lim, Yan-Lue; Ee, Robson; Yong, Delicia; Tee, Kok-Keng; Yin, Wai-Fong; Chan, Kok-Gan

    2015-11-20

    Pandoraea pnomenusa RB-38 is a bacterium isolated from a former sanitary landfill site. Here, we present the complete genome of P. pnomenusa RB38 in which an oxalate utilization pathway was identified. The genome analysis suggested the potential of this strain as an effective biocontrol agent against oxalate-producing phytopathogens. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Evaluation of blood--brain barrier permeability changes in rhesus monkeys and man using 82Rb and positron emission tomography

    International Nuclear Information System (INIS)

    Yen, C.K.; Budinger, T.F.

    1981-01-01

    Dynamic positron tomography of the brain with 82 Rb, obtained from a portable generator [ 82 Sr (25 days) -- 82 Rb (76 sec)], provides a means of studying blood-brain barrier (BBB) permeability in physiological and clinical investigations. The BBB in rhesus monkeys was opened unilaterally by intracarotid infusion of 3 M urea. This osmotic barrier opening allowed entry into the brain of intravenously administered rubidium chloride. The BBB opening was demonstrated noninvasively using 82 Rb and positron emission tomography and corroborated by the accumulation of 86 Rb in tissue samples. Positron emission tomography studies can be repeated every 5 min and indicate that dynamic tomography or static imaging can be used to study BBB permeability changes induced by a wide variety of noxious stimuli. Brain tumors in human subjects are readily detected because of the usual BBB permeability disruption in and around the tumors

  1. The assignment of dissociative electron attachment bands in compounds containing hydroxyl and amino groups

    International Nuclear Information System (INIS)

    Skalicky, Tomas; Allan, Michael

    2004-01-01

    Dissociative electron attachment (DEA) spectra were recorded for methanol, phenol, diethylamine, tetramethylhydrazine, piperazine, pyrrole and N,N-dimethylaniline. Comparison with He I photoelectron spectra permitted the assignment of virtually all DEA bands in the saturated compounds to core excited Feshbach resonances with double occupation of Rydberg-like orbitals and various Koopmans' states of the positive ion as a core. These resonances shift to lower energies with alkyl substitution, in contrast to the shape resonances, and are found at surprisingly low energies in the amines. The DEA spectra in the unsaturated compounds show no or only weak evidence for the Rydberg-type Feshbach resonances. It is proposed that DEA in saturated polyatomic molecules containing hydroxyl and amino groups is in general dominated by this type of resonance

  2. Coupled fast-thermal system at the RB, masters thesis; Spregnuti brzo-termicki sistem na reaktoru RB, magistarski rad

    Energy Technology Data Exchange (ETDEWEB)

    Pesic, M [Boris Kidric Institute of nuclear sciences Vinca, Belgrade (Yugoslavia)

    1984-05-15

    Coupled fast-thermal system at the RB reactor was formed owing to availability of highly enriched fuel. This paper deals with reactor parameters calculations and measurements of coupled core taking into account safety constraints. Validity of applied calculation methods was confirmed. The following parameters were analyzed: critical height of the core; reactivity dependent on heavy water level in the core; fast neutron spectrum in the fast region channel; spatial distribution of thermal. epithermal and fat neutrons in the fast region channel; reactivity of safety rods; neutron and gamma absorption doses in the center of the coupled core.

  3. High-precision branching-ratio measurement for the superallowed β+ emitter 74Rb

    Science.gov (United States)

    Dunlop, R.; Ball, G. C.; Leslie, J. R.; Svensson, C. E.; Towner, I. S.; Andreoiu, C.; Chagnon-Lessard, S.; Chester, A.; Cross, D. S.; Finlay, P.; Garnsworthy, A. B.; Garrett, P. E.; Glister, J.; Hackman, G.; Hadinia, B.; Leach, K. G.; Rand, E. T.; Starosta, K.; Tardiff, E. R.; Triambak, S.; Williams, S. J.; Wong, J.; Yates, S. W.; Zganjar, E. F.

    2013-10-01

    A high-precision branching-ratio measurement for the superallowed β+ decay of 74Rb was performed at the TRIUMF Isotope Separator and Accelerator (ISAC) radioactive ion-beam facility. The scintillating electron-positron tagging array (SCEPTAR), composed of 10 thin plastic scintillators, was used to detect the emitted β particles; the 8π spectrometer, an array of 20 Compton-suppressed HPGe detectors, was used for detecting γ rays that were emitted following Gamow-Teller and nonanalog Fermi β+ decays of 74Rb; and the Pentagonal Array of Conversion Electron Spectrometers (PACES), an array of 5 Si(Li) detectors, was employed for measuring β-delayed conversion electrons. Twenty-three excited states were identified in 74Kr following 8.241(4)×108 detected 74Rb β decays. A total of 58 γ-ray and electron transitions were placed in the decay scheme, allowing the superallowed branching ratio to be determined as B0=99.545(31)%. Combined with previous half-life and Q-value measurements, the superallowed branching ratio measured in this work leads to a superallowed ft value of 3082.8(65) s. Comparisons between this superallowed ft value and the world-average-corrected Ft¯ value, as well as the nonanalog Fermi branching ratios determined in this work, provide guidance for theoretical models of the isospin-symmetry-breaking corrections in this mass region.

  4. Ion-molecular equilibria and activity determination in the RbF-ZrF4 system

    International Nuclear Information System (INIS)

    Skokan, E.V.; Nikitin, M.I.; Sorokin, I.D.; Korenev, Yu.M.; Sidorov, L.N.

    1983-01-01

    Activity of zirconium tetrofluoride in 100-33.3 mol % ZrF 4 concentration range was determined during isothermal evaporation of samples of different initial composition of RbF-ZrF 4 system, using ion-molecular equilibrium method. It became possible, using the exchange ion-molecular reactions to determine ZrF 4 activity approximately 10 -10 in the region of state diagram of RbF-ZrF 4 system, adjoining to rubidium fluoride. The comparative analysis of results, obtained by the methods of isothermal evaporation, ion-molecular equilibria is given; the advantages and restrictions of ion-molecular equilibrium method are presented

  5. Optical conductivity in A3C60 (A=K, Rb)

    NARCIS (Netherlands)

    Brink, J. van den; Gunnarsson, O.; Eyert, V.

    1997-01-01

    Published in: Phys. Rev. B 57 (1998) 2163-2167 Citing articles (CrossRef) citations recorded in [Science Citation Index] Abstract: We study the optical conductivity in A3C60 (A =K, Rb). The effects of the electron-phonon interaction is included to lowest order in the coupling strength lambda. It is

  6. Rb-Sr ages and palaeomagnetic data for some Angolan alkaline intrusives

    International Nuclear Information System (INIS)

    Allsopp, H.L.; Hargraves, R.B.

    1985-01-01

    New Rb-Sr age measurements are reported for a number of intrusives from Angola. Data for the Njoio and Tchivira nepheline syenite bodies yield mineral isochrons indicating ages of 104,3+-0,8 Ma and 130,8+-1,4 Ma respectively. Palaeomagnetic studies on the same occurrences gave marginal and scattered results respectively. Micas from the Camafuca crater-facies kimberlite yielded and apparent age of 1 822+-151 Ma, a result that is far in excess of the Tertiary (or younger) age inferred for this pipe. Similarly conflicting data were obtained for the Nova Lisboa kimberlite. It is likely that older crustal micas incorporated in the kimberlite breccias are responsible for the anomalous ages reported on the kimberlites. Satisfactory palaeomagnetic data are reported for the Zenza and Bailundu occurrences, not dated by the Rb-Sr method. A convenient K-Ar age of 80+-0,8 Ma was obtainable for Zenza

  7. Ginsenoside Rb1 Protects Neonatal Rat Cardiomyocytes from Hypoxia/Ischemia Induced Apoptosis and Inhibits Activation of the Mitochondrial Apoptotic Pathway

    Directory of Open Access Journals (Sweden)

    Xu Yan

    2014-01-01

    Full Text Available Aim. To investigate the effect of Ginsenoside Rb1 (GS-Rb1 on hypoxia/ischemia (H/I injury in cardiomyocytes in vitro and the mitochondrial apoptotic pathway mediated mechanism. Methods. Neonatal rat cardiomyocytes (NRCMs for the H/I groups were kept in DMEM without glucose and serum, and were placed into a hypoxic jar for 24 h. GS-Rb1 at concentrations from 2.5 to 40 µM was given during hypoxic period for 24 h. NRCMs injury was determined by MTT and lactate dehydrogenase (LDH leakage assay. Cell apoptosis, ROS accumulation, and mitochondrial membrane potential (MMP were assessed by flow cytometry. Cytosolic translocation of mitochondrial cytochrome c and Bcl-2 family proteins were determined by Western blot. Caspase-3 and caspase-9 activities were determined by the assay kit. Results. GS-Rb1 significantly reduced cell death and LDH leakage induced by H/I. It also reduced H/I induced NRCMs apoptosis induced by H/I, in accordance with a minimal reactive oxygen species (ROS burst. Moreover, GS-Rb1 markedly decreased the translocation of cytochrome c from the mitochondria to the cytosol, increased the Bcl-2/ Bax ratio, and preserved mitochondrial transmembrane potential (ΔΨm. Its administration also inhibited activities of caspase-9 and caspase-3. Conclusion. Administration of GS-Rb1 during H/I in vitro is involved in cardioprotection by inhibiting apoptosis, which may be due to inhibition of the mitochondrial apoptotic pathway.

  8. Evaluation and application of alumina-based Rb-82 generators charged with high levels of Sr-82/85

    International Nuclear Information System (INIS)

    Yano, Y.; Budinger, T.F.; Chiang, G.; O'Brien, H.A.; Grant, P.M.

    1979-01-01

    Generator-produced Rb-82, a 75-sec positron emitter with potential for myocardial blood-flow imaging, was studied with various ion-exchange columns to evaluate the characteristics of alumina as an adsorber for the 25-day Sr-82 parent. Test columns of alumina, Bio Rex 70, and Chelex 100 were loaded with multimillicurie amounts of no-carrier-added Sr-82/Sr-85 (Sr-85 is a production contaminant). The breakthrough of Sr-82/Sr-85, and the yield of Rb-82, were determined for long-term elutions from each column with up to 4 liter of 2% NaCl solution at pH 8 to 9. The breakthrough of Sr-82/85 was 10 -6 to 10 -5 from alumina and 10 -6 to 10 -4 from Chelex 100 and Bio Rex 70. The effects of eluent flow rate and concentration, and of alumina volume, on the breakthrough and yield were also studied. An improved and automated Rb-82 generator was used for myocardial and brain blood-flow studies in experimental animals and in man; it was equipped with solenoid flow-control valves and five in. of lead shielding for the alumina columns, which were charged with 25 to 50 mCi Sr-82 (100 to 150 mCi Sr-85). The Rb-82 generator with alumina column provided up to 20 to 40 mCi of Rb-82 as often as every 5 to 10 min with -5 breakthrough of Sr-82/85 over the 2- to 3-mo, useful life of the generator

  9. Interaction of xenone difluoride with the fluorocomplexes of lanthanides and rubidium of the Rb3M3F6 composition

    International Nuclear Information System (INIS)

    Goryachenkov, S.A.; Fadeeva, N.E.; Kiselev, Yu.M.; Martynenko, L.I.; Spitsyn, V.I.

    1984-01-01

    The possibility of preparing rubidium fluorocomplexes of tetravalent lanthanides of the Rb 3 M 4 F 7 composition from Rb 3 M 3 F 6 (M 3 =Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho, Er, Tm, Yb) with XeF 2 has been studied. By the DTA method it is shown that Ce and Pr salts are fluorinated respectively at approximately 100 and approximately 235 deg C with a noticeable exoeffect. Tb and Dy salts fluorination proceeds with considerable kinetic difficulties. The fluorination products composition, Rb 3 M 4 F 7 (M 4 =Ce, Pr, Tb, Dy) is confirmed by the methods of chemical, IR-spectroscopic and X-ray phase analyses. XeF 2 interaction with Rb 3 M 3 F 6 salts of other lanthanides up to 400 deg C has not been observed

  10. Thermal, optical, and dielectric properties of fluoride Rb2TaF7

    Science.gov (United States)

    Pogorel'tsev, E. I.; Mel'nikova, S. V.; Kartashev, A. V.; Gorev, M. V.; Flerov, I. N.; Laptash, N. M.

    2017-05-01

    The thermal, optical, and dielectric properties of fluoride Rb2TaF7 were investigated. It was observed that the variation in chemical pressure in fluorides A 2 +TaF7 caused by the cation substitution of rubidium for ammonium does not affect the ferroelastic nature of structural distortions, but leads to stabilization of the high- and low-temperature phases and enhancement of birefringence. The entropy of the phase transition P4/nmm ↔ Cmma is typical of the shift transformations, which is consistent with a model of the initial and distorted phase structures. The anisotropy of chemical pressure causes the change of signs of the anomalous strain and baric coefficient dT/ dp of Rb2TaF7 as compared with the values for its ammonium analog.

  11. Crystal-structural study of zirconium chelates with alkali metals of composition A2[Zr(Nta)2]·xH2O (A=Li, Na, K, Rb, Cs or CH3H6)

    International Nuclear Information System (INIS)

    Sadikov, G.G.; Antsyshkina, A.S.; Sergienko, V.S.

    1997-01-01

    Some zirconium complexes with nitrile triacetate and with alkali metal in the external sphere were studied crystalostructurally. Packing of complexes and extra-sphere cations was studied. Plane or slightly corrugated anion layers of two essentially different types arranged according to the principle of trigonal and square grids represent the standard element of crystal structure. Water molecules are located both in anion and cation layers. CN and coordination polyhedron of cations are different even in case of stereotype nature of reasons of their location in the interlayer space. In Cs-, Rb- and K- compounds polyhedrons of alkali metal form specific doubled chains. These compounds are not isomorphous ones and are characterized by a specific way of water molecule location. Structure of sodium compound differs fundamentally from other ones. Ionic conductivity may be expected in crystals. 4 refs., 6 figs., 2 tabs

  12. Nuclear excitations in plasmas: the case of 84mRb

    International Nuclear Information System (INIS)

    Denis-Petit, David

    2014-01-01

    This experimental and theoretical work deals with the Nuclear Excitation by Electron Transition (NEET) process which involves a coupling between the nucleus and its electron cloud. In this process, an electron de-excitation can induce a nuclear excitation if the atomic and nuclear transitions are resonant and have the same multipolarity. This process could be observed in a laser created plasma of 84 Rb because this nucleus has a low energy transition (around 3 keV) between the isomeric state (J π = 6 - ,T 1/2 = 20,26 m) and the J π p= 5 - (T 1/2 = 9 ns) state. To evaluate a NEET excitation rate, the atomic states in plasma must be described and the nuclear transition must be precisely characterised. To describe the atomic states in plasma, a method based on a MCDF (Multi-Configuration Dirac-Fock) code was developed. This one uses a procedure to select the most probable atomic configurations according to the plasma properties. This method was checked by the interpretation of a X-rays spectrum emitted by a Rb plasma. This plasma was produced by the PHELIX laser of the GSI laboratory at an intensity of 6*10 14 W/cm 2 . The energy of the nuclear transition between the states 6 - and 5 - was not accurate enough for the NEET rate evaluation. Two γ-rays spectroscopy experiments were conducted at the ELSA accelerator from CEA/DAM/DIF and at the Tandem accelerator from the Orsay laboratory. The accuracy of the nuclear transition energy was improved of more than one order of magnitude. In this work, the NEET rate was evaluated to predict an experiment. The Rb plasma must have a high temperature (around 400 eV) to obtain a sufficient number of excited isomers and therefore to make possible the detection. (author)

  13. Short-lived isomers in 94Rb

    International Nuclear Information System (INIS)

    Tsekhanovich, I.; Dare, J. A.; Smith, A. G.; Varley, B. J.; Simpson, G. S.; Urban, W.; Soldner, T.; Jolie, J.; Linnemann, A.; Orlandi, R.; Smith, J. F.; Scherillo, A.; Rzaca-Urban, T.; Zlomaniec, A.; Dorvaux, O.; Gall, B. J. P.; Roux, B.

    2008-01-01

    The medium-spin structure of the neutron-rich, odd-odd nucleus 94 Rb was studied by means of γ-ray spectroscopy. Excited levels were populated in the neutron-induced fission of 235 U and in the spontaneous fission of 252 Cf and 248 Cm. Two isomeric states were found at 1485.2 and 2074.8 keV with half-lives of 18 and 107 ns, respectively. The probable structures of the two isomers involve the fully aligned, proton-neutron configurations [π(g 9/2 ) x ν(g 7/2 )] 8 + and [π(g 9/2 ) x ν(h 11/2 )] 10 - , respectively. These new data give information on the single-particle energies in the region

  14. Parallel beam powder diffraction study on the A1C60 system (A=K, Rb)

    International Nuclear Information System (INIS)

    Faigel, G.; Tegze, M.; Bortel, G.; Forro, L.; Oszlanyi, G.; Stephens, P.W.

    1994-01-01

    We report x-ray powder diffraction studies on Rb x C 60 and K x C 60 . It is shown that at room temperature there exist stoichiometric compounds in the Rb x C 60 and K x C 60 systems at the x = 1 composition. Their equilibrium structures are pseudo body centered orthorhombic. The C 60 -C 60 intermolecular separation (9.1 A) is the shortest among the known alkali-fullerides. A first order phase transition is observed at about 380 K from the high temperature fcc phase to the room temperature orthorhombic phase. (orig.)

  15. Rb-Sr Isotopic Systematics of Alkali-Rich Fragments in the Yamato-74442 LL-Chondritic Breccia

    Science.gov (United States)

    Yokoyama, T.; Misawa, K.; Okano, O.; Shih, C.-Y.; Nyquist, L. E.; Simo, J. I.; Tappa, M. J.; Yoneda, S.

    2012-01-01

    Alkali-rich igneous fragments were identified in the brecciated LL-chondrites, Kr henberg (LL5)], Bhola (LL3-6) and Yamato (Y)-74442 (LL4), and show characteristic fractionation patterns of alkaline elements. The K-Rb-Cs-rich fragments in Kr henberg, Bhola, and Y-74442 are very similar in mineralogy and petrography (olivine + pyroxene + glass), suggesting that they could have come from related precursor materials. We have undertaken Rb-Sr isotopic studies on alkali-rich fragments in Y-74442 to precisely determine their crystallization ages and the isotopic signatures of their precursor material(s).

  16. Booster vaccination with safe, modified, live-attenuated mutants of Brucella abortus strain RB51 vaccine confers protective immunity against virulent strains of B. abortus and Brucella canis in BALB/c mice.

    Science.gov (United States)

    Truong, Quang Lam; Cho, Youngjae; Kim, Kiju; Park, Bo-Kyoung; Hahn, Tae-Wook

    2015-11-01

    Brucella abortus attenuated strain RB51 vaccine (RB51) is widely used in prevention of bovine brucellosis. Although vaccination with this strain has been shown to be effective in conferring protection against bovine brucellosis, RB51 has several drawbacks, including residual virulence for animals and humans. Therefore, a safe and efficacious vaccine is needed to overcome these disadvantages. In this study, we constructed several gene deletion mutants (ΔcydC, ΔcydD and ΔpurD single mutants, and ΔcydCΔcydD and ΔcydCΔpurD double mutants) of RB51 with the aim of increasing the safety of the possible use of these mutants as vaccine candidates. The RB51ΔcydC, RB51ΔcydD, RB51ΔpurD, RB51ΔcydCΔcydD and RB51ΔcydCΔpurD mutants exhibited significant attenuation of virulence when assayed in murine macrophages in vitro or in BALB/c mice. A single intraperitoneal immunization with RB51ΔcydC, RB51ΔcydD, RB51ΔcydCΔcydD or RB51ΔcydCΔpurD mutants was rapidly cleared from mice within 3 weeks, whereas the RB51ΔpurD mutant and RB51 were detectable in spleens until 4 and 7 weeks, respectively. Vaccination with a single dose of RB51 mutants induced lower protective immunity in mice than did parental RB51. However, a booster dose of these mutants provided significant levels of protection in mice against challenge with either the virulent homologous B. abortus strain 2308 or the heterologous Brucella canis strain 26. In addition, these mutants were found to induce a mixed but T-helper-1-biased humoral and cellular immune response in immunized mice. These data suggest that immunization with a booster dose of attenuated RB51 mutants provides an attractive strategy to protect against either bovine or canine brucellosis.

  17. RB Research nuclear reactor, Annual report for 2005

    International Nuclear Information System (INIS)

    Milosevic, M.; Dasic, N.; Ljubenov, V.; Pesic, M.; Nikolic, D; Jevremovic, M.; Minic, D.

    2006-01-01

    Report on RB reactor operation during 2005 contains 3 parts. Part one contains a brief description of the reactor, reactor operation and operational capabilities, reactor components, relevant dosimetry and radiation protection issues, personnel and financial data. Part two is devoted to maintenance of the reactor components, namely, fuel, heavy water, reactor vessel, heavy water circulation system, absorption rods and heavy water level meters, maintenance of electronic, mechanical, electrical and auxiliary equipment. Part three contains data concerned with reactor operation during 2005

  18. Purification and Characterization of a Ginsenoside Rb1-Hydrolyzing β-Glucosidase from Aspergillus niger KCCM 11239

    Directory of Open Access Journals (Sweden)

    Kyung Hoon Chang

    2012-09-01

    Full Text Available Rb1-hydrolyzing β-glucosidase from Aspergillus niger KCCM 11239 was studied to develop a bioconversion process for minor ginsenosides. The specific activity of the purified enzyme was 46.5 times greater than that of the crude enzyme. The molecular weight of the native enzyme was estimated to be approximately 123 kDa. The optimal pH of the purified enzyme was pH 4.0, and the enzyme proved highly stable over a pH range of 5.0–10.0. The optimal temperature was 70 °C, and the enzyme became unstable at temperatures above 60 °C. The enzyme was inhibited by Cu2+, Mg2+, Co2+, and acetic acid (10 mM. In the specificity tests, the enzyme was found to be active against ginsenoside Rb1, but showed very low levels of activity against Rb2, Rc, Rd, Re, and Rg1. The enzyme hydrolyzed the 20-C,β-(1→6-glucoside of ginsenoside Rb1 to generate ginsenoside Rd and Rg3, and hydrolyzed 3-C,β-(1→2-glucoside to generate F2. The properties of the enzyme indicate that it could be a useful tool in biotransformation applications in the ginseng industry, as well as in the development of novel drug compounds.

  19. Computer monitoring of the RB reactor operation

    International Nuclear Information System (INIS)

    Milovanovic, S.; Pesic, M.; Milovanovic, T.

    1998-01-01

    Personal computer based acquisition system designed for monitoring of operation of the RB experimental reactor in the Institute of Nuclear Sciences 'Vinca' (former 'Boris Kidric') and experiences acquired during its use are shown in this paper. The monitoring covers generally all nuclear aspects of the reactor operation (start-up, nominal power operation, power changing, shut down and maintenance), but the emphasis is put on: real time (especially fast changing) reactivity measurement; supervising time dependence of the safety rods positions during shut down, and detection of position inaccuracy or failure operation of safety/control rods during the reactor operation or maintenance. (author)

  20. Data of evolutionary structure change: 1ONAD-2D3RB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ONAD-2D3RB 1ONA 2D3R D B ADTIVAVELDTYPNTDIGDPSYPHIGIDIKSVRSKKTAK...WNMQNGKVGTAHIIYNSVDKRLSAVVSYPNADSATVSYDVDLDNVLPEWVRVGLSASTGLYKETNTILSWSFTSKLKT------NALHFMFNQFSKDQKDLILQGDAT...pdbID>1ONA D 1ONAD TRVSSNGSPQG

  1. Splicing aberrations caused by constitutional RB1 gene mutations in ...

    Indian Academy of Sciences (India)

    in this family revealed skipping of exon 22 in three members of this family. In one proband, a ... This study reveals novel effects of RB1 mutations on splicing and suggests the utility of RNA analysis as an ... of life) and presence of multiple tumors (multifocal). The ..... spliced RNA have been linked to parent of origin as well as.

  2. Collection of $^{83}$Rb at low implantation energy for KATRIN

    CERN Multimedia

    Zboril, M

    KATRIN, the KArlsruhe TRItium Neutrino experiment aims to measure the neutrino mass by spectroscopy of the tritium $\\beta$-decay at the endpoint by means of Magnetic Adiabatic Collimation combined with an Electrostatic filter (MAC-E filter). To monitor the HV-system of the KATRIN-setup, we would need one or two $^{83}$Rb sources roughly every half a year.

  3. Synthesis, Crystal Structure, and Nonlinear Optical Properties of a New Alkali and Alkaline Earth Metal Carbonate RbNa5Ca5(CO38

    Directory of Open Access Journals (Sweden)

    Qiaoling Chen

    2016-12-01

    Full Text Available A new nonlinear optical (NLO material, RbNa5Ca5(CO38, has been synthesized by the hydrothermal method. The crystal structure is established by single-crystal X-ray diffraction. RbNa5Ca5(CO38 crystallizes in the hexagonal crystal system with space group P63mc (No. 186. The structure of RbNa5Ca5(CO38 can be described as the adjacent infinite [CaCO3]∞ layers lying in the a-b plane bridged through standing-on-edge [CO3] groups by sharing O atoms (two-fold coordinated to build a framework with four types of tunnels running through the b-axis. The Rb, Na, and [Na0.67Ca0.33] atoms reside in these tunnels, respectively. The measurement of second harmonic generation (SHG indicated that RbNa5Ca5(CO38 is a phase-matchable material, which had SHG responses of approximately 1×KH2PO4 (KDP. Meanwhile, the results from the UV-VIS diffuse reflectance spectroscopy study of the powder samples indicated that the UV cut-off edges of RbNa5Ca5(CO38 is about 203 nm.

  4. Chemical State of Radiobromine Formed by the Rb{sup 85}(n, {alpha}) Br{sup 82} Reaction; Etat Chimique Du Ra Diobrome Forme Par La Reaction {sup 85}Rb (n, {alpha}) {sup 82}Br; 0425 0418 041c 0418 0427 0415 0421 041a 041e 0415 0421 041e 0421 0422 041e 042f 041d 0418 0415 0420 0410 0414 0418 041e 0410 041a 0422 0418 0412 041d 041e 0413 041e 0411 0420 041e 041c 0410 , 041e 0411 0420 0410 0417 041e 0412 0410 041d 041d 041e 0413 041e 041f 0420 0418 0420 0415 0410 041a 0426 0418 0418 Rb{sup 85}(n, {alpha}) Br{sup 82}; Estado Quimico Del Radiobromo Formado Por La Reaccion {sup 85}Rb (n, {alpha}) {sup 82}Br

    Energy Technology Data Exchange (ETDEWEB)

    Vlatkovic, M.; Kauiic, S. [' ' Ruder Boskovic' ' Institute, Zagreb, Yugoslavia (Croatia)

    1965-04-15

    A study has been made of the chemical distribution of radiobromine between its higher (BrO{sup -}{sub 3}) and lower (Br{sup -}, Br{sub 2}, BrO{sup -}) oxidation states produced by nuclear reaction Rb{sup 85}(n, {alpha}) Br{sup 82} in a number of rubidium inorganic solids. The samples of dried Rb{sub 2}SO{sub 4}, Rb{sub 2}S{sub 2}O{sub 8}, RbMnO{sub 4}, RbNO{sub 3}, Rb{sub 2}CO{sub 3} and RblO{sub 3} were irradiated with 14 MeV neutrons by a (T + d) neutron generator. It appeared that in the case of Rb{sub 2}SO{sub 4} irradiated at room temperature or at -195 C approximately 8% of total Br{sup 82} activity was found in the bromate fraction, the rest following the bromide fraction. The room temperature irradiation of RbMnO{sub 4} and RbNO{sub 3} yielded about 1% of activity in the higher oxidation state of bromine and in the cases of Rb{sub 2}S{sub 2}O{sub 8} , Rb{sub 2}CO{sub 3} and RblO{sub 3} activity could be measured only in the bromide fraction. A small increase of the bromate activity was observed when neutron-irradiated Rb{sub 2}SO{sub 4} was heated up to 250 Degree-Sign C. At higher temperatures (up to 500 Degree-Sign C) the activity passed into the lower oxidation state. Theheating of the irradiated RbMnO{sub 4} and RbNO{sub 3} did not provoke any oxidation of bromine activity. While in the case of RbNO{sub 3} pre-irradiation {gamma}-dose of 22 Mrad had no influence upon the distribution of bromine recoils, the analysis of Rb{sub 2}SO{sub 4} pretreated with {gamma}-rays (55 Mrad) gave higher bromate activity compared with the samples that before neutron irradiation had only been dried at 150 Degree-Sign C. In conclusion the authors stress the significance of the chemical constitution of the target compound and non-isotopic media with regard to the distribution of highly energetic Br{sup 82} atoms and to their inability to anneal in the rubidium compounds investigated. (author) [French] Le memoire traite de la repartition, entre ses etats d

  5. Influence of B-Complex Vitamins on the Pharmacokinetics of Ginsenosides Rg1, Rb1, and Ro After Oral Administration.

    Science.gov (United States)

    Zheng, Peihe; Chen, Yinbin; Fu, Yangyang; Wang, Hecheng; Wang, Jia; Zheng, Siwen; Xiao, Shengyuan; Wang, Yingping

    2017-11-01

    After cultivation of ginseng, ginsenosides, which are the major active ingredients of gingeng, were approved for use by the food industry, and began to be used as added functional ingredients to try to improve the quality and price of functional foods. However, the interaction between different types of ginsenosides and nutrients needs further study. We investigated the effect of B-complex vitamins (which are essential nutrients) on the pharmacokinetics of the ginsenosides protopanaxatriol-type saponin Rg 1 , protopanaxadiol-type saponin Rb 1 , and oleanolic acid-type saponin Ro after oral administration. Ginsenosides Rg 1 , Rb 1 , and Ro, with or without B-complex vitamins, respectively, were administered orally to rats to evaluate their pharmacokinetics. The concentration of ginsenosides in plasma was determined by liquid chromatography/tandem mass spectrometry. Pharmacokinetic parameters were fitted using WinNonlin v6.2. After oral coadministration with B-complex vitamins, the area under the concentration-time curve from zero to infinity (AUC 0-∞ ) of ginsenoside Rg 1 was reduced by 70%, that of ginsenoside Rb 1 was reduced by 43%, and that of ginsenoside Ro was reduced by 34%. The AUC 0-∞ of ginsenosides Rg 1 and Rb 1 showed significant differences between different treatments, but the AUC 0-∞ of ginsenoside Ro did not. These results suggest significant ginsenoside-nutrient interactions between ginsenosides Rg 1 , Rb 1 , and B-complex vitamins.

  6. Rb2Na(NO33: A Congruently Melting UV-NLO Crystal with a Very Strong Second-Harmonic Generation Response

    Directory of Open Access Journals (Sweden)

    Guohong Zou

    2016-04-01

    Full Text Available Crystals of congruently melting noncentrosymmetric (NCS mixed alkali metal nitrate, Rb2Na(NO33, have been grown through solid state reactions. The material possesses layers with NaO8 hexagonal bipyramids and NO3 triangular units. Rb+ cations are residing in the interlayer space. Each NaO8 hexagonal bipyramid shares its corners and edges with two and three NO3 units, respectively, in order to fulfill a highly dense stacking in the unit cell. The NaO8 groups share their six oxygen atoms in equatorial positions with three different NO3 groups to generate a NaO6-NO3 layer with a parallel alignment. The optimized arrangement of the NO3 groups and their high density in the structure together produce a strong second-harmonic generation (SHG response. Powder SHG measurements indicate that Rb2Na(NO33 has a strong SHG efficiency of five times that of KH2PO4 (KDP and is type I phase-matchable. The calculated average nonlinear optical (NLO susceptibility of Rb2Na(NO33 turns out to be the largest value among the NLO materials composed of only [NO3]− anion. In addition, Rb2Na(NO33 exhibits a wide transparency region ranging from UV to near IR, which suggests that the compound is a promising NLO material.

  7. Evidence of nontermination of collective rotation near the maximum angular momentum in Rb75

    Science.gov (United States)

    Davies, P. J.; Afanasjev, A. V.; Wadsworth, R.; Andreoiu, C.; Austin, R. A. E.; Carpenter, M. P.; Dashdorj, D.; Finlay, P.; Freeman, S. J.; Garrett, P. E.; Görgen, A.; Greene, J.; Grinyer, G. F.; Hyland, B.; Jenkins, D. G.; Johnston-Theasby, F. L.; Joshi, P.; Macchiavelli, A. O.; Moore, F.; Mukherjee, G.; Phillips, A. A.; Reviol, W.; Sarantites, D.; Schumaker, M. A.; Seweryniak, D.; Smith, M. B.; Svensson, C. E.; Valiente-Dobon, J. J.; Ward, D.

    2010-12-01

    Two of the four known rotational bands in Rb75 were studied via the Ca40(Ca40,αp)Rb75 reaction at a beam energy of 165 MeV. Transitions were observed up to the maximum spin Imax of the assigned configuration in one case and one-transition short of Imax in the other. Lifetimes were determined using the residual Doppler shift attenuation method. The deduced transition quadrupole moments show a small decrease with increasing spin, but remain large at the highest spins. The results obtained are in good agreement with cranked Nilsson-Strutinsky calculations, which indicate that these rotational bands do not terminate, but remain collective at Imax.

  8. Atom-solid binding energy shifts for K 2p and Rb 3d sublevels

    International Nuclear Information System (INIS)

    Holappa, M.; Aksela, S.; Patanen, M.; Urpelainen, S.; Aksela, H.

    2011-01-01

    Highlights: → Binding energy shifts between atom and solid. K 2p and Rb 3d sublevels were studied. → Simultaneous measurements give accurate results. → Results can be used as a reference for cluster studies. - Abstract: Binding energy shifts between free and solid state atoms for K 2p and Rb 3d photolines have been determined by measuring the vapor and solid state spectra simultaneously in similar experimental conditions applying synchrotron radiation excited photoelectron spectroscopy. This method has the important benefit that the work function is not needed to correct for different reference energy levels, therefore much more accurate values for binding energy shifts are obtained.

  9. Heritable factors for radiation-induced osteosarcoma and the role of Rb1 in telomere maintenance in mesenchymal stem cells

    International Nuclear Information System (INIS)

    Rosemann, M.; Gonzalez-Vasconcellos, I.; Atkinson, M. J.

    2013-01-01

    Full text: Secondary tumors following a pediatric radiotherapy become an ever growing concern, a side effect of the improved therapeutic success leading to extended life span of the patients. Osteosarcoma (OS) and other soft-tissue sarcomas arise over proportionally frequent in the radiation field of former radiooncology patients. In an effort to map and identify inherited factors that govern individual susceptibility for these secondary, therapy associated tumors, we developed a mouse model that after injection of 227 thorium develops high numbers of OS and facilitates whole genome mapping of genetic variants that modify risk. We could identify genetic risk factors on 5 different chromosomes, that by independent segregation in the germline can interact in an additive manner and in combination alter the individual risk more than 3 fold. Using additional in-vitro studies and mouse knockout technology we could confirm that the responsible gene on the principal susceptibility locus is Rb1. Mice with a bone-specific Rb1+/- status exhibits increased bone tumor risk following irradiation. We have shown recently that the Rb1 tumor suppressor gene does not only regulates the cell cycle kinetics of mammalian cells, but that in normal osteoblasts is also crucial to protect telomeres from extensive erosion. An Rb1+/- deficiency therefore exhibit accelerated telomeric loss and, following ionising irradiation an excess of chromosomal defects. In the majority of secondary RT associated human OS, Rb1 was affected by allelic loss, whereas spontaneous human OS with no known radiation etiology show only 15%-20% Rb1 losses. It is assumed that the target cells for malignant transformation leading to OS are not the differentiating osteoblasts, but rather the long-term repopulating and pluripotent mesenchymal stem cells (MSC). These normal tissue stem cells are assumed to maintain a high degree of genome stability throughout the entire life span of an organism. One of the key factors

  10. Mutation of purD and purF genes further attenuates Brucella abortus strain RB51.

    Science.gov (United States)

    Truong, Quang Lam; Cho, Youngjae; Barate, Abhijit Kashinath; Kim, Suk; Watarai, Masahisa; Hahn, Tae-Wook

    2015-02-01

    In the present study, transposon mutagenesis was used to further attenuate Brucella abortus RB51 vaccine strain. Two purD and purF mutants were constructed, characterized and evaluated for attenuation via intracellular survival in murine macrophage-like RAW264.7 and HeLa cells, and by clearance in BALB/c mice. The purD and purF mutants showed significantly decreased intracellular survival, and complementation of these mutants with intact copies of purD or purF genes of RB51 strain was able to restore these defects. In addition, the pur mutants presented significantly lowered persistence in mice. Immunization with purD and purF mutants protected mice against a challenge with the virulent B. abortus strain 544 at a level similar to that of the parent RB51. These data suggest that genes encoding the early stages of purine biosynthesis (purD and purF) are required for intracellular survival and virulence of B. abortus. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Electrical resistance, superconductivity and phase transformations of Rb and Cs under high pressure

    International Nuclear Information System (INIS)

    Ullrich, K.

    1980-01-01

    Four lead electrical resistance measurements were performed on Rb under pressures up to 210 kbar for temperatures in the range 0.05 K to 300 K. Pressure was applied using a Bridgman-anvil-configuration with dense sintered diamond in the highly stressed tip regions of the Carboloy pistons. The sample cell was pressurized at room temperature by a mechanical press connected to the mixing chamber of a 3 He- 4 He-cryostat. The pressure remained essentially constant during cooling. Discontinuous changes in resistance at pressures of 70 and 140 kbar indicate two phase transitions and confirm the results of other authors. The resistance of Rb increases after a minimum at 20 kbar by about two orders of magnitude. (orig.) [de

  12. Magnetic field-induced modification of selection rules for Rb D 2 line monitored by selective reflection from a vapor nanocell

    Science.gov (United States)

    Klinger, Emmanuel; Sargsyan, Armen; Tonoyan, Ara; Hakhumyan, Grant; Papoyan, Aram; Leroy, Claude; Sarkisyan, David

    2017-08-01

    Magnetic field-induced giant modification of the probabilities of five transitions of 5S1 / 2,Fg = 2 → 5P3 / 2,Fe = 4 of 85Rb and three transitions of 5S1 / 2,Fg = 1 → 5P3 / 2,Fe = 3 of 87Rb forbidden by selection rules for zero magnetic field has been observed experimentally and described theoretically for the first time. For the case of excitation with circularly-polarized (σ+) laser radiation, the probability of Fg = 2,mF = - 2 → Fe = 4,mF = - 1 transition becomes the largest among the seventeen transitions of 85Rb Fg = 2 → Fe = 1,2,3,4 group, and the probability of Fg = 1, mF = - 1 → Fe = 3,mF = 0 transition becomes the largest among the nine transitions of 87Rb Fg = 1 → Fe = 0,1,2,3 group, in a wide range of magnetic field 200-1000 G. Complete frequency separation of individual Zeeman components was obtained by implementation of derivative selective reflection technique with a 300 nm-thick nanocell filled with Rb, allowing formation of narrow optical resonances. Possible applications are addressed. The theoretical model is well consistent with the experimental results.

  13. Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects.

    Science.gov (United States)

    Berman, Seth D; West, Julie C; Danielian, Paul S; Caron, Alicia M; Stone, James R; Lees, Jacqueline A

    2009-09-01

    The retinoblastoma tumor-suppressor protein, pRb, is a member of the pocket protein family that includes p107 and p130. These proteins have well-defined roles in regulating entry into and exit from the cell cycle and also have cell cycle-independent roles in facilitating differentiation. Here we investigate the overlap between pocket protein's function during embryonic development by using conditional mutant alleles to generate Rb;p107 double-mutant embryos (DKOs) that develop in the absence of placental defects. These DKOs die between e13.5 and e14.5, much earlier than either the conditional Rb or the germline p107 single mutants, which survive to birth or are largely viable, respectively. Analyses of the e13.5 DKOs shows that p107 mutation exacerbates the phenotypes resulting from pRb loss in the central nervous system and lens, but not in the peripheral nervous system. In addition, these embryos exhibit novel phenotypes, including increased proliferation of blood vessel endothelial cells, and heart defects, including double-outlet right ventricle (DORV). The DORV is caused, at least in part, by a defect in blood vessel endothelial cells and/or heart mesenchymal cells. These findings demonstrate novel, overlapping functions for pRb and p107 in numerous murine tissues.

  14. Geochronological studies by Rb/Sr method in rocks of the Jundiai block and surroundings. [Ampario group

    Energy Technology Data Exchange (ETDEWEB)

    Wernick, E [Faculdade de Filosofia Ciencias e Letras de Rio Claro; Oliveira, M A.F. de; Kawashita, K; Cordani, U G [Sao Paulo Univ. (Brazil). Inst. de Geociencias; Delhal, J [Musee Royal de l' Afrique Centrale, Belgica

    1976-01-01

    Field and petrological data, as well as radiometric results performed in granulitic, gneissic, migmatitic, and granitic rocks from the 'Jundiai tectonic block' (States of Sao Paulo and Minas Gerais), show for that region the existence of two superposed orogeneses. To the older, of transamazonian age whole rock Rb-Sr isochron 2,010 m.y. Rb/sup 87//Sr/sup 86/ initial = 0.702), belongs the Amparo Group, composed of gneisses, migmatites, and granulites, with intercalation of quartzites, schists and calc-silicate rocks. To the younger, of brazilian age whole rock Rb-Sr isochron 690 m.y. (Sr/sup 87//Sr/sup 86/ initial = 0.702), are related the feldspathization and migmatization of the Amparo Group, as well as the intrusion of granitic bodies. Possibly, also the metasediments around Jacarei belong to the brazilian cycle. This pattern of geologic evolution is similar to that observed for the Serra dos Orgaos region (States of Rio de Janeiro and Minas Gerais).

  15. Synthesis and Characterization of the Ternary Thiobismuthates A9Bi13S24 (A = K, Rb)

    KAUST Repository

    Davaasuren, Bambar

    2016-11-16

    Ternary alkali metal thiobismuthates ABiS (A = K, Rb) were synthesized by direct combination reactions at 650 °C. The compounds crystallize in the monoclinic space group C2/m (no. 12) with cell parameters a = 30.919(1) Å, b = 4.1008(2) Å, c = 20.9072(9) Å, β = 105.826(3)° for KBiS (1) and a = 31.823(6) Å, b = 4.1177(8) Å, c = 21.086(4) Å, β = 105.62(3)° for RbBiS (2). The crystal structure of 1 contains a 3D [KBiS] polyanionic framework, whereas 2 consists of 2D [RbBiS] polyanionic slabs stacked along [201]. Both 1 and 2 are semiconductors with a band gap of 1.4 and 1.3 eV, respectively, which is supported by an electronic structure calculation. 1 melts congruently at 580 °C, while 2 melts incongruently at 575 °C. 1 and 2 are airstable and insoluble in water and organic solvents.

  16. Zero energy reactor RB technical characteristics and experimental possibilities

    Energy Technology Data Exchange (ETDEWEB)

    Jovanovic, S; Takac, S; Raisic, N; Lolic, B; Markovic, H [Boris Kidric Institute of Nuclear Sciences Vinca, Beograd (Yugoslavia)

    1963-04-15

    The zero energy reactor RB was constructed in 1958 in accordance with the nuclear reactor development programme of the Boris Kidric Institute of Nuclear Sciences. The reactor was in operation until the middle of 1959 when the heavy water, serving as the moderator, was transported to the high flux reactor RA, built at the same time at the Boris Kidric Institute. Owing to the fact that the purchase of new quantities of heavy water was planned for 1961 it was decided to reconstruct the RB reactor in order to improve the safety of the system and to obtain better flexibility in performing the experiments. New control, safety and radiation monitoring systems were constructed. Some changes were also made on the reactor tank, water circulation system and the water level monitoring equipment. The reconstruction was completed in 1961. and the heavy water was delivered early in 1962. The reconstructed reactor was critical for the first time in summer 1962, and from that time was in continuous operation. This report presents an outline of the design and construction characteristics of the reactor. The main intention is to inform potential users of the reactor about experimental possibilities, advantages and disadvantages of such a critical facility.

  17. Zero energy reactor RB technical characteristics and experimental possibilities

    International Nuclear Information System (INIS)

    Jovanovic, S.; Takac, S.; Raisic, N.; Lolic, B.; Markovic, H.

    1963-04-01

    The zero energy reactor RB was constructed in 1958 in accordance with the nuclear reactor development programme of the Boris Kidric Institute of Nuclear Sciences. The reactor was in operation until the middle of 1959 when the heavy water, serving as the moderator, was transported to the high flux reactor RA, built at the same time at the Boris Kidric Institute. Owing to the fact that the purchase of new quantities of heavy water was planned for 1961 it was decided to reconstruct the RB reactor in order to improve the safety of the system and to obtain better flexibility in performing the experiments. New control, safety and radiation monitoring systems were constructed. Some changes were also made on the reactor tank, water circulation system and the water level monitoring equipment. The reconstruction was completed in 1961. and the heavy water was delivered early in 1962. The reconstructed reactor was critical for the first time in summer 1962, and from that time was in continuous operation. This report presents an outline of the design and construction characteristics of the reactor. The main intention is to inform potential users of the reactor about experimental possibilities, advantages and disadvantages of such a critical facility

  18. Interaction of antiprotons with Rb atoms and a comparison of antiproton stopping powers of the atoms H, Li, Na, K, and Rb

    DEFF Research Database (Denmark)

    Lühr, Armin Christian; Fischer, Nicolas; Saenz, Alejandro

    2009-01-01

    Ionization and excitation cross sections as well as electron-energy spectra and stopping powers of the alkali metal atoms Li, Na, K, and Rb colliding with antiprotons were calculated using a time-dependent channel-coupling approach. An impact-energy range from 0.25 to 4000 keV was considered....... The target atoms are treated as effective one-electron systems using a model potential. The results are compared with calculated cross sections for antiproton-hydrogen atom collisions....

  19. Experimental studies of the NaRb ground-state potential up to the v''=76 level

    International Nuclear Information System (INIS)

    Docenko, O.; Nikolayeva, O.; Tamanis, M.; Ferber, R.; Pazyuk, E.A.; Stolyarov, A.V.

    2002-01-01

    Laser induced fluorescence spectra of the C 1 Σ + -X 1 Σ + system of 23 Na 85 Rb and 23 Na 87 Rb have allowed vibrational levels of the electronic ground state up to v '' =76, spanning 99.85% of the potential well to be observed. The ground-state term values have been fitted to a Dunham polynomial expansion, and also to a direct modified Lennard-Jones (MLJ) potential. The analytical MLJ construction allowed us to match previous measured term values for v '' ≤30 with long-range behavior of the potential through the intermediate internuclear distance region covered by the present investigation

  20. Structural phase transitions in CsPbCl/sub 3/ and RbCdCl/sub 3/

    Energy Technology Data Exchange (ETDEWEB)

    Plesko, S; Kind, R; Roos, J [Swiss Federal Inst. of Technology, Zuerich. Lab. of Solid State Physics

    1978-08-01

    Structural phase transitions in CsPbCl/sub 3/ have been investigated by /sup 133/Cs and /sup 87/Rb nuclear magnetic resonance. The space groups of the room temperature phase in CsPbCl/sub 3/ and of two unknown phases in RbCdCl/sub 3/ could be clarified. Thus both perovskites show the same phase sequence from cubic Pm3m-O sub(h)sup(1) to tetragonal P4/mbm-D sub(4h)sup(5), orthorhombic Cmcm-D sub(2h)sup(17) and further orthorhombic Pnma-D sub(2h)sup(16).