WorldWideScience

Sample records for rapidly gaining experience

  1. Determinants of rapid weight gain during infancy: baseline results from the NOURISH randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Mihrshahi Seema

    2011-11-01

    Full Text Available Abstract Background Rapid weight gain in infancy is an important predictor of obesity in later childhood. Our aim was to determine which modifiable variables are associated with rapid weight gain in early life. Methods Subjects were healthy infants enrolled in NOURISH, a randomised, controlled trial evaluating an intervention to promote positive early feeding practices. This analysis used the birth and baseline data for NOURISH. Birthweight was collected from hospital records and infants were also weighed at baseline assessment when they were aged 4-7 months and before randomisation. Infant feeding practices and demographic variables were collected from the mother using a self administered questionnaire. Rapid weight gain was defined as an increase in weight-for-age Z-score (using WHO standards above 0.67 SD from birth to baseline assessment, which is interpreted clinically as crossing centile lines on a growth chart. Variables associated with rapid weight gain were evaluated using a multivariable logistic regression model. Results Complete data were available for 612 infants (88% of the total sample recruited with a mean (SD age of 4.3 (1.0 months at baseline assessment. After adjusting for mother's age, smoking in pregnancy, BMI, and education and infant birthweight, age, gender and introduction of solid foods, the only two modifiable factors associated with rapid weight gain to attain statistical significance were formula feeding [OR = 1.72 (95%CI 1.01-2.94, P = 0.047] and feeding on schedule [OR = 2.29 (95%CI 1.14-4.61, P = 0.020]. Male gender and lower birthweight were non-modifiable factors associated with rapid weight gain. Conclusions This analysis supports the contention that there is an association between formula feeding, feeding to schedule and weight gain in the first months of life. Mechanisms may include the actual content of formula milk (e.g. higher protein intake or differences in feeding styles, such as feeding to schedule

  2. Early rapid weight gain and subsequent overweight and obesity in middle childhood in Peru.

    Science.gov (United States)

    Penny, Mary E; Jimenez, M Michelle; Marin, R Margot

    2016-01-01

    Rapid postnatal weight gain is associated with risk of overweight and obesity, but it's unclear whether this holds in populations exposed to concurrent obesogenic risk factors and for children who have been extensively breastfed. This study investigates whether an increase in weight for age from birth to 1 year (infancy) and from 1 to 5 years (early childhood) predicts overweight and obesity, and waist circumference at 8 years, using data from a longitudinal cohort study in Peru. Generalized estimating equations (GEE) models were constructed for overweight and obesity, obesity alone and waist circumference at 8 years versus rapid weight gain in infancy, and early childhood including adjusted models to account for confounders. Rapid weight gain in both periods was associated with double the risk of overweight and obesity, obesity alone at 8 years and increased waist circumference even after controlling for maternal BMI and education level, sex of child, height-for-age at 8 years, consumption of "fast food" and number of days of active exercise. The association was significant, with some differences, for children in both rural and urban environments. Rapid weight gain in infancy and in early childhood in Peru is associated with overweight and obesity at age 8 years even when considering other determinants of childhood obesity.

  3. High gain requirements and high field Tokamak experiments

    International Nuclear Information System (INIS)

    Cohn, D.R.

    1994-01-01

    Operation at sufficiently high gain (ratio of fusion power to external heating power) is a fundamental requirement for tokamak power reactors. For typical reactor concepts, the gain is greater than 25. Self-heating from alpha particles in deuterium-tritium plasmas can greatly reduce ητ/temperature requirements for high gain. A range of high gain operating conditions is possible with different values of alpha-particle efficiency (fraction of alpha-particle power that actually heats the plasma) and with different ratios of self heating to external heating. At one extreme, there is ignited operation, where all of the required plasma heating is provided by alpha particles and the alpha-particle efficiency is 100%. At the other extreme, there is the case of no heating contribution from alpha particles. ητ/temperature requirements for high gain are determined as a function of alpha-particle heating efficiency. Possibilities for high gain experiments in deuterium-tritium, deuterium, and hydrogen plasmas are discussed

  4. Radiographic and computed tomographic demonstration of pseudotumor cerebri due to rapid weight gain in a child with pelvic rhabdomyosarcoma

    Energy Technology Data Exchange (ETDEWEB)

    Berdon, W.E.; Barker, D.H.; Barash, F.S.

    1982-06-01

    Rapid weight gain in a malnourished child can be associated with suture diastasis in the pattern of pseudotumor cerebri; this has been previously reported in deprivational dwarfism and cystic fibrosis. In a child with pelvic rhabdomyosarcoma, skull radiographs and cranial computed tomographic (CT) scans were available prior to a period of rapid weight gain induced by hyperalimentation. Suture diastasis developed and repeat CT scans showed this to be accompanied by smaller ventricles.

  5. Radiographic and computed tomographic demonstration of pseudotumor cerebri due to rapid weight gain in a child with pelvic rhabdomyosarcoma

    International Nuclear Information System (INIS)

    Berdon, W.E.; Barker, D.H.; Barash, F.S.

    1982-01-01

    Rapid weight gain in a malnourished child can be associated with suture diastasis in the pattern of pseudotumor cerebri; this has been previously reported in deprivational dwarfism and cystic fibrosis. In a child with pelvic rhabdomyosarcoma, skull radiographs and cranial computed tomographic (CT) scans were available prior to a period of rapid weight gain induced by hyperalimentation. Suture diastasis developed and repeat CT scans showed this to be accompanied by smaller ventricles

  6. Extreme Rapid Weight Loss and Rapid Weight Gain Observed in UK Mixed Martial Arts Athletes Preparing for Competition.

    Science.gov (United States)

    Matthews, Joseph John; Nicholas, Ceri

    2017-04-01

    There is a lack of research documenting the weight-making practices of mixed-martial-arts (MMA) competitors. The purpose of the investigation was to quantify the magnitude and identify the methods of rapid weight loss (RWL) and rapid weight gain (RWG) in MMA athletes preparing for competition. Seven athletes (mean ± SD, age 24.6 ± 3.5 yrs, body mass 69.9 ± 5.7 kg, competitive experience 3.1 ± 2.2 yrs) participated in a repeated-measures design. Measures of dietary intake, urinary hydration status, and body mass were recorded in the week preceding competition. Body mass decreased significantly (p < .0005) from baseline by 5.6 ± 1.4 kg (8 ± 1.8%). During the RWG period (32 ± 1 hr) body mass increased significantly (p < .001) by 7.4 ± 2.8 kg (11.7 ± 4.7%), exceeding RWL. Mean energy and carbohydrate intake were 3176 ± 482 kcal・day -1 and 471 ± 124 g・day -1 , respectively. At the official weigh-in 57% of athletes were dehydrated (1033 ± 19 mOsmol・kg -1 ) and the remaining 43% were severely dehydrated (1267 ± 47 mOsmol・kg -1 ). Athletes reported using harmful dehydration-based RWL strategies, including sauna (43%) and training in plastic suits (43%). Results demonstrated RWG greater than RWL, this is a novel finding and may be attributable to the 32 hr duration from weigh-in till competition. The observed magnitude of RWL and strategies used are comparable to those which have previously resulted in fatalities. Rule changes which make RWL impractical should be implemented with immediate effect to ensure the health, safety and wellbeing of competitors.

  7. Prenatal organochlorine compound exposure, rapid weight gain, and overweight in infancy.

    Science.gov (United States)

    Mendez, Michelle A; Garcia-Esteban, Raquel; Guxens, Mónica; Vrijheid, Martine; Kogevinas, Manolis; Goñi, Fernando; Fochs, Silvia; Sunyer, Jordi

    2011-02-01

    Although it has been hypothesized that fetal exposure to endocrine-disrupting chemicals may increase obesity risk, empirical data are limited, and it is uncertain how early in life any effects may begin. We explored whether prenatal exposure to several organochlorine compounds (OCs) is associated with rapid growth in the first 6 months of life and body mass index (BMI) later in infancy. Data come from the INMA (Infancia y Medio-Ambiente) Child and Environment birth cohort in Spain, which recruited 657 women in early pregnancy. Rapid growth during the first 6 months was defined as a change in weight-for-age z-scores > 0.67, and elevated BMI at 14 months, as a z-score ≥ the 85th percentile. Generalized linear models were used to estimate the risk of rapid growth or elevated BMI associated with 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene (DDE), hexachlorobenzene, β-hexachlorohexane, and polychlorinated biphenyls in first-trimester maternal serum. After multivariable adjustment including other OCs, DDE exposure above the first quartile was associated with doubling of the risk of rapid growth among children of normal-weight (BMI < 25 kg/m2), but not overweight, mothers. DDE was also associated with elevated BMI at 14 months (relative risk per unit increase in log DDE = 1.50; 95% confidence interval, 1.11-2.03). Other OCs were not associated with rapid growth or elevated BMI after adjustment. In this study we found prenatal DDE exposure to be associated with rapid weight gain in the first 6 months and elevated BMI later in infancy, among infants of normal-weight mothers. More research exploring the potential role of chemical exposures in early-onset obesity is needed.

  8. Transition Program: The Challenges Faced by Special Needs Students in Gaining Work Experience

    Science.gov (United States)

    Alias, Aliza

    2014-01-01

    Transition program for special needs students is known to open opportunities for students with learning disabilities to gain work experience in actual work environment. The program provides training activities and also an opportunity to go for internship to gain work experience. Therefore, this study is to identify the challenges faced by special…

  9. Prenatal exposure to traffic pollution: associations with reduced fetal growth and rapid infant weight gain.

    Science.gov (United States)

    Fleisch, Abby F; Rifas-Shiman, Sheryl L; Koutrakis, Petros; Schwartz, Joel D; Kloog, Itai; Melly, Steven; Coull, Brent A; Zanobetti, Antonella; Gillman, Matthew W; Gold, Diane R; Oken, Emily

    2015-01-01

    Prenatal air pollution exposure inhibits fetal growth, but implications for postnatal growth are unknown. We assessed weights and lengths of US infants in the Project Viva cohort at birth and 6 months. We estimated 3rd-trimester residential air pollution exposures using spatiotemporal models. We estimated neighborhood traffic density and roadway proximity at birth address using geographic information systems. We performed linear and logistic regression adjusted for sociodemographic variables, fetal growth, and gestational age at birth. Mean birth weight-for-gestational age z-score (fetal growth) was 0.17 (standard deviation [SD] = 0.97; n = 2,114), 0- to 6-month weight-for-length gain was 0.23 z-units (SD = 1.11; n = 689), and 17% had weight-for-length ≥95th percentile at 6 months of age. Infants exposed to the highest (vs. lowest) quartile of neighborhood traffic density had lower fetal growth (-0.13 units [95% confidence interval (CI) = -0.25 to -0.01]), more rapid 0- to 6-month weight-for-length gain (0.25 units [95% CI = 0.01 to 0.49]), and higher odds of weight-for-length ≥95th percentile at 6 months (1.84 [95% CI = 1.11 to 3.05]). Neighborhood traffic density was additionally associated with an infant being in both the lowest quartile of fetal growth and the highest quartile of 0- to 6-month weight-for-length gain (Q4 vs. Q1, odds ratio = 3.01 [95% CI = 1.08 to 8.44]). Roadway proximity and 3rd-trimester black carbon exposure were similarly associated with growth outcomes. For 3rd-trimester particulate matter (PM2.5), effect estimates were in the same direction, but smaller and imprecise. Infants exposed to higher traffic-related pollution in early life may exhibit more rapid postnatal weight gain in addition to reduced fetal growth.

  10. Early rapid weight gain and subsequent overweight and obesity in middle childhood in Peru

    OpenAIRE

    Penny, Mary E.; Jimenez, M. Michelle; Marin, R. Margot

    2016-01-01

    Background Rapid postnatal weight gain is associated with risk of overweight and obesity, but it?s unclear whether this holds in populations exposed to concurrent obesogenic risk factors and for children who have been extensively breastfed. This study investigates whether an increase in weight for age from birth to 1?year (infancy) and from 1 to 5?years (early childhood) predicts overweight and obesity, and waist circumference at 8?years, using data from a longitudinal cohort study in Peru. M...

  11. EBO feed water distribution system, experience gained from operation

    Energy Technology Data Exchange (ETDEWEB)

    Matal, O. [Energovyzkum, Brno (Switzerland); Schmidt, S.; Mihalik, M. [Atomove Elektrarne Bohunice, Jaslovske Bohunice (Switzerland)

    1997-12-31

    Advanced feed water distribution systems of the EBO design have been installed into steam generators at Units 3 and 4 of the NPP Jaslovske Bohunice (VVER 440). Experiences gained from the operation of steam generators with the advanced feed water distribution systems are discussed in the paper. (orig.). 4 refs.

  12. EBO feed water distribution system, experience gained from operation

    Energy Technology Data Exchange (ETDEWEB)

    Matal, O [Energovyzkum, Brno (Switzerland); Schmidt, S; Mihalik, M [Atomove Elektrarne Bohunice, Jaslovske Bohunice (Switzerland)

    1998-12-31

    Advanced feed water distribution systems of the EBO design have been installed into steam generators at Units 3 and 4 of the NPP Jaslovske Bohunice (VVER 440). Experiences gained from the operation of steam generators with the advanced feed water distribution systems are discussed in the paper. (orig.). 4 refs.

  13. Impediments to User Gains: Experiences from a Critical Participatory Design Project

    DEFF Research Database (Denmark)

    Bossen, Claus; Dindler, Christian; Iversen, Ole Sejer

    2012-01-01

    interviews with participants in a project aimed at developing technology that fosters engaging museum experiences, and rethinking cultural heritage communication. Despite the use of established PD techniques by experienced PD practitioners, a significant number of frustrations relating to the PD process were...... prominent in the research study. Based on these findings, we provide an analysis of impediments for users gains in PD projects: Differences between aims were unresolved, absence of a shared set-up for collaboration and different conceptions of technology.......Actual studies of user gains from involvement in design processes are few, although a concern for users’ gains is a core characteristic of participatory design (PD). We explore the question of user gains through a retrospective evaluation of a critical PD project. We conducted ten qualitative...

  14. Rapid pile load tests in the geotechnical centrifuge

    NARCIS (Netherlands)

    Holscher, P.; Van Tol, A.F.; Huy, N.Q.

    2012-01-01

    Centrifiige experiments were carried out to gain insight into the factors that affect the mobilized resistance during rapid load testing on piles in sand. The influence of generated pore water pressure during rapid load tests is shidied, and its effect on the commonly used unloadmg point method to

  15. Experience gained in enhancing operational safety at ComEd's nuclear power plants

    International Nuclear Information System (INIS)

    Elias, D.

    1997-01-01

    The following aspects of experience gained in enhancing operational safety at Comed's nuclear power plants are discussed: nuclear safety policy; centralization/decentralization; typical nuclear operating organization; safety review boards; human performance enhancement; elements of effective nuclear oversight

  16. Experience and Methodology gained from 4 years of Student Satellite Projects

    DEFF Research Database (Denmark)

    Alminde, Lars; Bisgaard, Morten; Bhanderi, Dan

    2005-01-01

    The AAU Cubesat student satellite project at Aalborg University was initiated in September 2001 and led to the launch of the satellite on the 30th of June 2003 with a “Rockot” rocket from Plesetsk in Russia. The satellite survived three months in orbit and based on the experiences gained the next...

  17. First lasing of a high-gain harmonic generation free-electron laser experiment.

    Energy Technology Data Exchange (ETDEWEB)

    Babzien, M.; Ben-Zvi, I.; Biedron, S. G.; DiMauro, L. F.; Douryan, A.; Galayda, J. N.; Gluskin, E.; Graves, W.; Jagger, J.; Johnson, E.; Krinsky, S.; Malone, R.; Pogorelsky, I.; Rakowsky, G.; Sajaev, V.; Skaritka, J.; Solomon, L.; Vasserman, I.; Wang, X. L.; Woodle, M.; Yakimenko, V.; Yu, L.-H.

    1999-09-11

    We report on the first lasing of a high-gain harmonic generation (HGHG) free-electron laser (FEL). The experiment was conducted at the Accelerator Test Facility (ATF) at Brookhaven National Laboratory (BNL). This is a BNL experiment in collaboration with the Advanced Photon Source (APS) at Argonne National Laboratory. A preliminary measurement gives a high-gain harmonic generation (HGHG) pulse energy that is 2 x 10{sup 7} times larger than the spontaneous radiation, In a purely self-amplified spontaneous emission (SASE) mode of operation, the signal was measured as 10 times larger than the spontaneous radiation in the same distance ({approximately}2 m) through the same wiggler. This means the HGHG signal is 2 x 10{sup 6} times larger than the SASE signal. To obtain the same saturated output power by the SASE process, the radiator would have to be 3 times longer (6 m).

  18. Regional Advection Perturbations in an Irrigated Desert (RAPID) Experiment

    NARCIS (Netherlands)

    Debruin, H.A.R.; Hartogensis, O.K.; Allen, R.G.; Kramer, J.W.J.L.

    2005-01-01

    The RAPID field experiment took place in August - September 1999 at a site 25km south of Twin Falls, Idaho, USA. The experiment concerned micrometeorological observations over extensive, well-irrigated fields covered with the fast-growing crop alfalfa. During daytime, on a number of days the

  19. Controlling gain one photon at a time

    Science.gov (United States)

    Schwartz, Gregory W; Rieke, Fred

    2013-01-01

    Adaptation is a salient property of sensory processing. All adaptational or gain control mechanisms face the challenge of obtaining a reliable estimate of the property of the input to be adapted to and obtaining this estimate sufficiently rapidly to be useful. Here, we explore how the primate retina balances the need to change gain rapidly and reliably when photons arrive rarely at individual rod photoreceptors. We find that the weakest backgrounds that decrease the gain of the retinal output signals are similar to those that increase human behavioral threshold, and identify a novel site of gain control in the retinal circuitry. Thus, surprisingly, the gain of retinal signals begins to decrease essentially as soon as background lights are detectable; under these conditions, gain control does not rely on a highly averaged estimate of the photon count, but instead signals from individual photon absorptions trigger changes in gain. DOI: http://dx.doi.org/10.7554/eLife.00467.001 PMID:23682314

  20. Radiation cooling and gain calculation for C VI 182 A line in C/Se plasma

    International Nuclear Information System (INIS)

    Nam, C.H.; Valeo, E.; Suckewer, S.; Feldman, U.

    1986-04-01

    A model is developed which is capable of describing the evolution of gain resulting from both rapid radiative and expansion cooling of a recombining, freely expanding plasma. It is demonstrated for the particular case of a carbon/selenium plasma that the cooling rate which leads to optimal gain can be achieved by adjusting the admixture of an efficiently radiating material (selenium) in the gain medium (carbon). Comparison is made to a recent observation of gain in a recent NRL/Rochester experiment with carbon/selenium plasma for the n = 3 → 2 transition in C VI occurring at 182 A. The predicted maximum gain is approx.10 cm -1 , as compared to observation of 2 to 3 cm -1

  1. Experience gained in enhancing operational safety at ComEd`s nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Elias, D [Commonwealth Edison Co. (United States)

    1997-09-01

    The following aspects of experience gained in enhancing operational safety at Comed`s nuclear power plants are discussed: nuclear safety policy; centralization/decentralization; typical nuclear operating organization; safety review boards; human performance enhancement; elements of effective nuclear oversight.

  2. Rapid acceleration leads to rapid weakening in earthquake-like laboratory experiments

    Science.gov (United States)

    Chang, J. C.; Lockner, D. A.; Reches, Z.

    2012-12-01

    We simulated the slip of a fault-patch during a large earthquake by rapidly loading an experimental, ring-shaped fault with energy stored in a spinning flywheel. The flywheel abruptly delivers a finite amount of energy by spinning the fault-patch that spontaneously dissipates the energy without operator intervention. We conducted 42 experiments on Sierra White granite (SWG) samples, and 24 experiments on Kasota dolomite (KD) samples. Each experiment starts by spinning a 225 kg disk-shaped flywheel to a prescribed angular velocity. We refer to this experiment as an "earthquake-like slip-event" (ELSE). The strength-evolution in ELSE experiments is similar to the strength-evolution proposed for earthquake models and observed in stick-slip experiments. Further, we found that ELSE experiments are similar to earthquakes in at least three ways: (1) slip driven by the release of a finite amount of stored energy; (2) pattern of fault strength evolution; and (3) seismically observed values, such as average slip, peak-velocity and rise-time. By assuming that the measured slip, D, in ELSE experiments is equivalent to the average slip during an earthquake, we found that ELSE experiments (D = 0.003-4.6 m) correspond to earthquakes in moment-magnitude range of Mw = 4-8. In ELSE experiments, the critical-slip-distance, dc, has mean values of 2.7 cm and 1.2 cm for SWG and KD, that are much shorter than the 1-10 m in steady-state classical experiments in rotary shear systems. We attribute these dc values, to ELSE loading in which the fault-patch is abruptly loaded by impact with a spinning flywheel. Under this loading, the friction-velocity relations are strikingly different from those under steady-state loading on the same rock samples with the same shear system (Reches and Lockner, Nature, 2010). We further note that the slip acceleration in ELSE evolves systematically with fault strength and wear-rate, and that the dynamic weakening is restricted to the period of intense

  3. Intra-pulse laser absorption sensor with cavity enhancement for oxidation experiments in a rapid compression machine

    KAUST Repository

    Nasir, Ehson Fawad

    2018-05-23

    A sensor based on a mid-IR pulsed quantum cascade laser (QCL) and off-axis cavity enhanced absorption spectroscopy (OA-CEAS) has been developed for highly sensitive concentration measurements of carbon monoxide (CO) in a rapid compression machine. The duty cycle and the pulse repetition rate of the laser were optimized for increased tuning range, high chirp rate, and small line width to achieve effective laser-cavity coupling. This enabled spectrally resolved CO line-shape measurements at high pressures (P ~10 bar). A gain factor of 133 and a time resolution of 10 μs were demonstrated. CO concentration-time profiles during the oxidation of highly dilute n-octane/air mixtures were recorded, illustrating new opportunities in RCM experiments for chemical kinetics.

  4. Best Practices for Achieving High, Rapid Reading Gains

    Science.gov (United States)

    Carbo, Marie

    2008-01-01

    The percentage of students who read at the proficient level on the National Assessment of Educational Progress (NAEP) has not improved, and is appallingly low. In order for students to achieve high reading gains and become life-long readers, reading comprehension and reading enjoyment must be the top two goals. This article presents several…

  5. Rapid acceleration leads to rapid weakening in earthquake-like laboratory experiments

    Science.gov (United States)

    Chang, Jefferson C.; Lockner, David A.; Reches, Z.

    2012-01-01

    After nucleation, a large earthquake propagates as an expanding rupture front along a fault. This front activates countless fault patches that slip by consuming energy stored in Earth’s crust. We simulated the slip of a fault patch by rapidly loading an experimental fault with energy stored in a spinning flywheel. The spontaneous evolution of strength, acceleration, and velocity indicates that our experiments are proxies of fault-patch behavior during earthquakes of moment magnitude (Mw) = 4 to 8. We show that seismically determined earthquake parameters (e.g., displacement, velocity, magnitude, or fracture energy) can be used to estimate the intensity of the energy release during an earthquake. Our experiments further indicate that high acceleration imposed by the earthquake’s rupture front quickens dynamic weakening by intense wear of the fault zone.

  6. The experience gained at various stages of the Atucha nuclear power plant project

    International Nuclear Information System (INIS)

    Cosentino, J.O.

    1977-01-01

    The paper describes the experience gained in Argentina at the successive stages of planning, feasibility study, decision-making, awarding of contracts, construction and operation of the first nuclear power plant in Latin America. In particular, the operating experience accumulated so far is summarized together with the requirements for preparing operating tables for the plant. The role of the Atucha plant is also described in connection with the second plant under construction and the third in the planning stage [es

  7. Gain attenuation of gated framing camera

    International Nuclear Information System (INIS)

    Xiao Shali; Liu Shenye; Cao Zhurong; Li Hang; Zhang Haiying; Yuan Zheng; Wang Liwei

    2009-01-01

    The theoretic model of framing camera's gain attenuation is analyzed. The exponential attenuation curve of the gain along the pulse propagation time is simulated. An experiment to measure the coefficient of gain attenuation based on the gain attenuation theory is designed. Experiment result shows that the gain follows an exponential attenuation rule with a quotient of 0.0249 nm -1 , the attenuation coefficient of the pulse is 0.00356 mm -1 . The loss of the pulse propagation along the MCP stripline is the leading reason of gain attenuation. But in the figure of a single stripline, the gain dose not follow the rule of exponential attenuation completely, instead, there is a gain increase at the stripline bottom. That is caused by the reflection of the pulse. The reflectance is about 24.2%. Combining the experiment and theory, which design of the stripline MCP can improved the gain attenuation. (authors)

  8. High gain direct drive target designs and supporting experiments with KrF

    International Nuclear Information System (INIS)

    Karasik, Max; Bates, Jason W.; Aglitskiy, Yefim

    2013-01-01

    Krypton-fluoride laser is an attractive inertial fusion energy driver from the standpoint of target physics. Target designs taking advantage of zooming, shock ignition, and favorable physics with KrF reach energy gains of 200 with sub-MJ laser energy. The designs are robust under 2D simulations. Experiments on the Nike KrF laser support the physics basis. (author)

  9. Observing floods from space: Experience gained from COSMO-SkyMed observations

    Science.gov (United States)

    Pierdicca, N.; Pulvirenti, L.; Chini, M.; Guerriero, L.; Candela, L.

    2013-03-01

    The COSMO-SkyMed mission offers a unique opportunity to obtain all weather radar images characterized by short revisit time, thus being useful for flood evolution mapping. The COSMO-SkyMed system has been activated several times in the last few years in occasion of flood events all over the world in order to provide very high resolution X-band SAR images useful for flood detection purposes. This paper discusses the major outcomes of the experience gained, within the framework of the OPERA Pilot Project funded by the Italian Space Agency, from using COSMO-SkyMed data for the purpose of near real time generation of flood maps. A review of the mechanisms which determine the imprints of the inundation on the radar images and of the fundamental simulation tools able to predict these imprints and help image interpretation is provided. The approach developed to process the data and to generate the flood maps is also summarized. Then, the paper illustrates the experience gained with COSMO-SkyMed by describing and discussing a number of significant examples. These examples demonstrate the potential of the COSMO-SkyMed system and the suitability of the approach developed for generating the final products, but they also highlight some critical aspects that require further investigations to improve the reliability of the flood maps.

  10. Gaining a Child: Comparing the Experiences of Biological Parents, Adoptive Parents, and Stepparents

    Science.gov (United States)

    Ceballo, Rosario; Lansford, Jennifer E.; Abbey, Antonia; Stewart, Abigail J.

    2004-01-01

    This study compares the experience of gaining a child through birth, adoption, or marriage, extending the focus of investigation beyond biological parenthood and the transition made by first-time parents. Using a subsample from the National Survey of Families and Households N=204, we compared reasons for having children, parental well-being,…

  11. Experience gained from the operation of two α-monitors in ''PUTE''

    International Nuclear Information System (INIS)

    Groll, P.; Persohn, M.; Roeder, L.; Roemer, J.; Schuler, B.

    1983-04-01

    The operation of two α-monitors of the ''drum-cell''-type in the plutonium facility ''PUTE'' is described. The instruments were installed in the AW- and the BW-stream. After a short description of the monitor, the different operating modes and of installation details, the experience gained from two weeks of continuous operation is described. The advantages of the use of in-line-instruments compared with laboratory analyses of samples are discussed. The instruments were available for 97 or 94% of the time. (orig.) [de

  12. Pains and Gains from China’s Experiences with Emerging Epidemics: From SARS to H7N9

    Directory of Open Access Journals (Sweden)

    Pengfei Wei

    2016-01-01

    Full Text Available Over the recent decades, China experienced several emerging virus outbreaks including those caused by the severe acute respiratory syndrome- (SARS- coronavirus (Cov, H5N1 virus, and H7N9 virus. The SARS tragedy revealed faults in China’s infectious disease prevention system, propelling the Chinese government to enact reforms that enabled better combating of the subsequent H1N1 and H7N9 avian flu epidemics. The system is buttressed by three fundamental, mutually reinforcing components: (1 enduring government administration reforms, including legislation establishing a unified public health emergency management system; (2 prioritized funding for biotechnology and biomedicine industrialization, especially in the areas of pathogen identification, drug production, and the development of vaccines and diagnostics; and (3 increasing investment for public health and establishment of a rapid-response infectious diseases prevention and control system. China is now using its hard-gained experience to support the fight against Ebola in Africa and the Middle East Respiratory Syndrome in its own country.

  13. Gain and loss learning differentially contribute to life financial outcomes.

    Directory of Open Access Journals (Sweden)

    Brian Knutson

    Full Text Available Emerging findings imply that distinct neurobehavioral systems process gains and losses. This study investigated whether individual differences in gain learning and loss learning might contribute to different life financial outcomes (i.e., assets versus debt. In a community sample of healthy adults (n = 75, rapid learners had smaller debt-to-asset ratios overall. More specific analyses, however, revealed that those who learned rapidly about gains had more assets, while those who learned rapidly about losses had less debt. These distinct associations remained strong even after controlling for potential cognitive (e.g., intelligence, memory, and risk preferences and socioeconomic (e.g., age, sex, ethnicity, income, education confounds. Self-reported measures of assets and debt were additionally validated with credit report data in a subset of subjects. These findings support the notion that different gain and loss learning systems may exert a cumulative influence on distinct life financial outcomes.

  14. Experience gained from fires in nuclear power plants: Lessons learned

    International Nuclear Information System (INIS)

    2004-11-01

    In 1993, the IAEA launched a programme to assist Member States in improving fire safety in nuclear power plants (NPPs). The review of fire safety assessment in many plants has shown that fire is one of the most important risk contributors for NPPs. Moreover, operational experience has confirmed that many events have a similar root cause, initiation and development mechanism. Therefore, many States have improved the analysis of their operational experience and its feedback. States that operate NPPs play an important role in the effort to improve fire safety by circulating their experience internationally - this exchange of information can effectively prevent potential events. When operating experience is well organized and made accessible, it can feed an improved fire hazard assessment on a probabilistic basis. The practice of exchanging operational experience seems to be bearing fruit: serious events initiated by fire are on the decline at plants in operating States. However, to maximize this effort, means for communicating operational experience need to be continuously improved and the pool of recipients of operational experience data enlarged. The present publication is the third in a series started in 1998 on fire events, the first two were: Root Cause Analysis for Fire Events (IAEA-TECDOC-1112) and Use of Operational Experience in Fire Safety Assessment of Nuclear Power Plants (IAEA-TECDOC-1134). This TECDOC summarizes the experience gained and lessons learned from fire events at operating plants, supplemented by specific Member State experiences. In addition, it provides a possible structure of an international fire and explosion event database aimed at the analysis of experience from fire events and the evaluation of fire hazard. The intended readership of this is operators of plants and regulators. The present report includes a detailed analysis of the most recent events compiled with the IAEA databases and other bibliographic sources. It represents a

  15. The ICAP Active Learning Framework Predicts the Learning Gains Observed in Intensely Active Classroom Experiences

    Directory of Open Access Journals (Sweden)

    Benjamin L. Wiggins

    2017-05-01

    Full Text Available STEM classrooms (science, technology, engineering, and mathematics in postsecondary education are rapidly improved by the proper use of active learning techniques. These techniques occupy a descriptive spectrum that transcends passive teaching toward active, constructive, and, finally, interactive methods. While aspects of this framework have been examined, no large-scale or actual classroom-based data exist to inform postsecondary education STEM instructors about possible learning gains. We describe the results of a quasi-experimental study to test the apex of the ICAP framework (interactive, constructive, active, and passive in this ecological classroom environment. Students in interactive classrooms demonstrate significantly improved learning outcomes relative to students in constructive classrooms. This improvement in learning is relatively subtle; similar experimental designs without repeated measures would be unlikely to have the power to observe this significance. We discuss the importance of seemingly small learning gains that might propagate throughout a course or departmental curriculum, as well as improvements with the necessity for faculty to develop and implement similar activities.

  16. Heavy inertial particles in turbulent flows gain energy slowly but lose it rapidly.

    Science.gov (United States)

    Bhatnagar, Akshay; Gupta, Anupam; Mitra, Dhrubaditya; Pandit, Rahul

    2018-03-01

    We present an extensive numerical study of the time irreversibility of the dynamics of heavy inertial particles in three-dimensional, statistically homogeneous, and isotropic turbulent flows. We show that the probability density function (PDF) of the increment, W(τ), of a particle's energy over a time scale τ is non-Gaussian, and skewed toward negative values. This implies that, on average, particles gain energy over a period of time that is longer than the duration over which they lose energy. We call this slow gain and fast loss. We find that the third moment of W(τ) scales as τ^{3} for small values of τ. We show that the PDF of power-input p is negatively skewed too; we use this skewness Ir as a measure of the time irreversibility and we demonstrate that it increases sharply with the Stokes number St for small St; this increase slows down at St≃1. Furthermore, we obtain the PDFs of t^{+} and t^{-}, the times over which p has, respectively, positive or negative signs, i.e., the particle gains or loses energy. We obtain from these PDFs a direct and natural quantification of the slow gain and fast loss of the energy of the particles, because these PDFs possess exponential tails from which we infer the characteristic loss and gain times t_{loss} and t_{gain}, respectively, and we obtain t_{loss}gain} for all the cases we have considered. Finally, we show that the fast loss of energy occurs with greater probability in the strain-dominated region than in the vortical one; in contrast, the slow gain in the energy of the particles is equally likely in vortical or strain-dominated regions of the flow.

  17. Designing Skin Cancer Prevention Messages: Should We Emphasize Gains or Losses? Message Framing, Risk Type, and Prior Experience.

    Science.gov (United States)

    Lee, Moon J; Kang, Hannah

    2018-05-01

    To test whether message framing (ie, gain vs. loss) and risk type (ie, health vs appearance risk) in skin cancer prevention messages interact with one's prior experience. Two experiments with a 2 (message framing: gain vs loss) × 2 (risk type: health vs appearance risk) factorial design were conducted. The participants were given a URL to the experiment website via e-mail. On the first page of the website, the participants were told that they would be asked to evaluate a skin cancer print public service announcement (PSA): Online experiments. A total of 397 individuals participated (236 for experiment 1 and 161 for experiment 2). Apparatus: Four versions of the skin cancer print PSAs were developed. Four PSAs were identical except for the 2 manipulated components: message framing and risk type. Measures were adopted from Cho and Boster (message framing), Jones and Leary and Kiene et al. (risk type), De Vries, Mesters, van't Riet, Willems, and Reubsaet and Knight, Kirincich, Farmer, and Hood (prior experience), and Hammond, Fong, Zanna, Thrasher, and Borland and Hoffner and Ye (behavioral intent). General linear models were used to test hypotheses. Three-way interactions among message framing, risk type, and prior experience were found: When the intent of the message was to encourage sunscreen use, the effects of message framing and risk type were shown to be the exact opposite directions from when the intent was to discourage indoor/outdoor tanning. To discourage tanning among those with prior experience, messages emphasizing losses in terms of one's health will work better. For those with no prior experience, messages emphasizing potential appearance losses will work better for discouraging tanning while messages emphasizing gains like improving appearance will do a better job in encouraging sunscreen use.

  18. Operational experience gained from the Central Brae subsea field

    International Nuclear Information System (INIS)

    Sapp, S.J.; Gomersall, S.D.

    1994-01-01

    The size of the field discoveries made in the North Sea in recent years has declined dramatically. With the low oil price many small fields are not viable stand alone developments. The North Sea has a large, well developed infrastructure of production facilities and pipelines. With many platforms now operating below optimum production rate, subsea tieback of these small fields utilizing the available processing capacity is the most economically attractive means of development. This paper presents a history of such a field development. The Central Brae field is located within the Brae complex of fields, 155 miles north east of Aberdeen, and has been developed by means of a subsea facility tied back to the Brae Alpha platform. A great deal of experience has been gained through the field development, not only in subsea operations but also in completion and template design and operating philosophy

  19. Predictors of rapid high weight gain in schizophrenia: Longitudinal analysis of the French FACE-SZ cohort.

    Science.gov (United States)

    Godin, O; Leboyer, M; Schürhoff, F; Boyer, L; Andrianarisoa, M; Brunel, L; Bulzacka, E; Aouizerate, B; Berna, F; Capdevielle, D; D'Amato, T; Denizot, H; Dubertret, C; Dubreucq, J; Faget, C; Gabayet, F; Llorca, P M; Mallet, J; Misdrahi, D; Passerieux, C; Rey, R; Richieri, R; Schandrin, A; Urbach, M; Vidailhet, P; Costagliola, D; Fond, G

    2017-11-01

    Metabolic syndrome (MetS) is highly prevalent in schizophrenia. However very little is known about the time course of MetS and its components. The few longitudinal studies that have been carried out had small sample sizes and a short follow-up. The aim of our study was to evaluate the prevalence of MetS and its components, at baseline and one year later, and to investigate predictors of weight gain (WG) in a cohort of individuals with schizophrenia. We followed 167 schizophrenia patients from the FACE-SZ cohort for one year. The Structured Clinical Interview for DSM-IV (SCID) was used to confirm the diagnosis of schizophrenia. Data on socio-demographic and clinical characteristics, antipsychotic treatment, and comorbidities were collected, and a blood sample was drawn. We found that the prevalence of MetS increased from 21.0% to 26.6% after one year. Patients with baseline depressive symptoms had a 4.5-fold higher risk of WG at the one-year follow-up (p = 0.02) than those without depressive symptoms, after adjusting for confounding variables. WG also correlated with high levels of metabolic parameters and peripheral inflammation. These findings highlight the need to systematically diagnose depression in Schizophrenia. Future studies should determine whether specific pharmacological and non-pharmacological interventions for depression in SZ subjects are effective in preventing rapid high weight gain. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Experience gained during Manufacture and Testing of the W7-X Superconducting Magnets

    International Nuclear Information System (INIS)

    Wanner, M.; Sborchia, C.; Risse, K.; Viebke, H.; Baldzuhn, J.

    2006-01-01

    The W7-X basic device is presently being assembled at the Greifswald branch of IPP. The specific field configurations of this helical advanced stellarator are realised by a symmetric arrangement of 50 non-planar and 20 planar superconducting coils. In order to sustain the large electromagnetic forces and moments, all coils are bolted to a massive coil support structure and supported against each other by inter-coil support elements. Cooling of superconductor and the casing is provided by supercritical helium. For all coils the same cable-in-conduit conductor is used. This conductor is formed by a NbTi cable which is co-extruded in an aluminium jacket. Low-resistive electrical joints connect the conductor layers within a winding package and potential break provide electrical insulation of the helium pipes. After insulation and vacuum pressure impregnation, the winding packages are embedded in stainless steel casings, which are then finish-machined and equipped with cooling pipes. During a rapid shut-down of the magnet system the windings may experience voltages up to several kilovolts. High voltage tests under degraded vacuum conditions (Paschen tests) provide a sensitive method to detect weak points in the electrical insulation. Manufacture of the magnets is in a well advanced stage. All winding packages are completed, many of them are integrated in the casings and several coils have already been delivered for cold testing. These tests are performed in a cryogenic test facility at CEA Saclay. Tests at nominal operating conditions and quench tests confirmed the electric layout and the specified margin. Design changes have been implemented during fabrication due to more detailed structural analyses. Some manufacturing processes had to be modified and re-qualified to allow repair of weaknesses defects found during tests. The presentation will give an overview of the production status of the superconducting coils, the experiences gained during fabrication of the

  1. A Laboratory Experiment for Rapid Determination of the Stability of Vitamin C

    Science.gov (United States)

    Adem, Seid M.; Lueng, Sam H.; Elles, Lisa M. Sharpe; Shaver, Lee Alan

    2016-01-01

    Experiments in laboratory manuals intended for general, organic, and biological (GOB) chemistry laboratories include few opportunities for students to engage in instrumental methods of analysis. Many of these students seek careers in modern health-related fields where experience in spectroscopic techniques would be beneficial. A simple, rapid,…

  2. Experience gained with energy taxes in Europe - Lessons for Switzerland

    International Nuclear Information System (INIS)

    Peter, M.; Lueckge, H.; Iten, R.; Trageser, J.; Goerlach, B.; Blobel, D.; Kraemer, A.

    2007-12-01

    This comprehensive final report for the Swiss Federal Office of Energy (SFOE) takes a look at experience gained with energy taxes in Europe and the lessons that can be learned for Switzerland. The variety of energy and CO 2 taxes that have been introduced in Europe since the early 1990s is reviewed. These are intended to reduce energy consumption and CO 2 emissions and complement conventional mineral oil taxes. Some of these non-fiscal energy and CO 2 taxes that have been created within the scope of the EU directive on energy taxation are examined and commented on, as is their impact on energy consumption. The situation in EU member states is described and commented on. Success-factors and general conditions are examined and conclusions that can be drawn for Switzerland are examined.

  3. Heavy inertial particles in turbulent flows gain energy slowly but lose it rapidly

    Science.gov (United States)

    Bhatnagar, Akshay; Gupta, Anupam; Mitra, Dhrubaditya; Pandit, Rahul

    2018-03-01

    We present an extensive numerical study of the time irreversibility of the dynamics of heavy inertial particles in three-dimensional, statistically homogeneous, and isotropic turbulent flows. We show that the probability density function (PDF) of the increment, W (τ ) , of a particle's energy over a time scale τ is non-Gaussian, and skewed toward negative values. This implies that, on average, particles gain energy over a period of time that is longer than the duration over which they lose energy. We call this slow gain and fast loss. We find that the third moment of W (τ ) scales as τ3 for small values of τ . We show that the PDF of power-input p is negatively skewed too; we use this skewness Ir as a measure of the time irreversibility and we demonstrate that it increases sharply with the Stokes number St for small St; this increase slows down at St≃1 . Furthermore, we obtain the PDFs of t+ and t-, the times over which p has, respectively, positive or negative signs, i.e., the particle gains or loses energy. We obtain from these PDFs a direct and natural quantification of the slow gain and fast loss of the energy of the particles, because these PDFs possess exponential tails from which we infer the characteristic loss and gain times tloss and tgain, respectively, and we obtain tlossprobability in the strain-dominated region than in the vortical one; in contrast, the slow gain in the energy of the particles is equally likely in vortical or strain-dominated regions of the flow.

  4. Experience gained at the CEA by thermal effluent utilization for agriculture and fish-breeding

    International Nuclear Information System (INIS)

    Balligand.

    1976-01-01

    Results obtained at the CEA for waste heat utilization are examined. Water at T+10 0 C is used for open air soil heating (forest, agriculture), eel breeding and greenhouse, heating (with the help of heat pumps). Water at T+23 0 C or 30 0 C is used for greenhouses. Facilities are described experience gained and results of the different exploitations are given [fr

  5. Land use impacts of rapid transit: implications of recent experience. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Knight, R.L.; Trygg, L.L.

    1977-08-01

    Evidence of land use impacts of recent major rapid transit improvements are reviewed and conclusions drawn concerning the extent and nature of such impacts and the conditions under which they have occurred. Transit improvements studied are primarily post-World War II in origin. American and Canadian examples are stressed, although European experience is teated briefly. Virtually all major modern American and Canadian rapid transit investments are included, covering conventional rapid rail, commuter rail, light rail and bus/busway. In addition to conclusions on general patterns of land use impact and causes, research recommendations and Federal policy implications are drawn.

  6. Gain characteristics of a multiatmosphere uv-preionized CO2 laser

    International Nuclear Information System (INIS)

    Alcock, A.J.; Fedosejevs, R.; Walker, A.C.

    1975-01-01

    The small-signal gain of a transverse-discharge UV-preionized CO 2 laser was investigated at pressures in the 1 to 15-atm range. Measurements were carried out on the P(18) and R(16) lines of both the 10.4- and 9.4-μm bands, and data on the pressure dependence of the peak gain and gain rise time are presented. The results demonstrate that small-signal gains in excess of 5-percent cm -1 are readily obtained at pressures of approximately 12 atm and confirm that the relaxation times of the energy levels relevant to laser action scale inversely with pressure. In addition, it is found that the gain of both R branches increases more rapidly with pressure than that of the P branches, while there are indications that the 9.4- and 10.4-μm gain values become comparable at pressures of approximately 15 atm. The experimental results are compared with the dependence of gain on pressure predicted by a relatively simple theoretical model. On the basis of this model it is found that the experimentally determined gain rises more rapidly with pressure than one would expect and a number of possible reasons for this discrepancy are discussed

  7. Sudden gains in group cognitive-behavioral therapy for panic disorder.

    Science.gov (United States)

    Clerkin, Elise M; Teachman, Bethany A; Smith-Janik, Shannan B

    2008-11-01

    The current study investigates sudden gains (rapid symptom reduction) in group cognitive-behavioral therapy for panic disorder. Sudden gains occurring after session 2 of treatment predicted overall symptom reduction at treatment termination and some changes in cognitive biases. Meanwhile, sudden gains occurring immediately following session 1 were not associated with symptom reduction or cognitive change. Together, this research points to the importance of examining sudden gains across the entire span of treatment, as well as the potential role of sudden gains in recovery from panic disorder.

  8. Operational experience gained with the failed fuel rod detection system in nuclear power plants

    International Nuclear Information System (INIS)

    Boehm, H.H.; Forch, H.

    1985-01-01

    Brown Boveri Reaktor GmbH together with Krautkramer Company developed such a FAILED FUEL ROD DETECTION SYSTEM (FFRDS) which allows to located defective fuel rods without dismantling the fuel assembly or pulling of individual rods. Since 1979 the FFRDS is employed successfully in various nuclear power plants in Europe, USA, Japan, and Korea. The short inspection time and the high reliability of the method make the FFRDS a true competitor to the sipping method. In this paper the authors discuss the method and the design of the system, the equipment set-up, its features and the experience gained so far. The system has been performed and automated to such an extent that within a short installation period series of fuel assemblies can be tested with relatively short intervals of time (5 minutes for BWR and 7 minutes for PWR fuel assemblies per side). The ability of the system for deployment under various conditions and the experience gained during the past six years have made this system universally applicable and highly sensitive to the requirements of NDT during outages and for transport of FAs to intermediate storage facilities. Comparison of FFRDS to conventional sipping has indicated in several instances that the FFRDS is superior to the latter technique

  9. Proton therapy detector studies under the experience gained at the CATANA facility

    International Nuclear Information System (INIS)

    Cuttone, G.; Cirrone, G.A.P.; Di Rosa, F.; Lojacono, P.A.; Lo Nigro, S.; Marino, C.; Mongelli, V.; Patti, I.V.; Pittera, S.; Raffaele, L.; Russo, G.; Sabini, M.G.; Salamone, V.; Valastro, L.M.

    2007-01-01

    Proton therapy represents the most promising radiotherapy technique for external tumor treatments. At Laboratori Nazionali del Sud of the Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania (I), a proton therapy facility is active since March 2002 and 140 patients, mainly affected by choroidal and iris melanoma, have been successfully treated. Proton beams are characterized by higher dose gradients and linear energy transfer with respect to the conventional photon and electron beams, commonly used in medical centers for radiotherapy. In this paper, we report the experience gained in the characterization of different dosimetric systems, studied and/or developed during the last ten years in our proton therapy facility

  10. Proton therapy detector studies under the experience gained at the CATANA facility

    Energy Technology Data Exchange (ETDEWEB)

    Cuttone, G.; Cirrone, G.A.P.; Di Rosa, F. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Lojacono, P.A. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Dipartimento di Fisica ed Astronomia, Universita degli Studi di Catania (Italy); Lo Nigro, S.; Marino, C. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Dipartimento di Fisica ed Astronomia, Universita degli Studi di Catania (Italy); Centro Siciliano di Fisica Nucleare e Struttura della Materia, Catania (Italy); Mongelli, V. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Dipartimento di Fisica ed Astronomia, Universita degli Studi di Catania (Italy); Patti, I.V. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Pittera, S. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Dipartimento di Fisica ed Astronomia, Universita degli Studi di Catania (Italy); Centro Siciliano di Fisica Nucleare e Struttura della Materia, Catania (Italy); Raffaele, L. [A.O.U. Policlinico, Universita degli Studi di Catania (Italy); Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Russo, G. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Dipartimento di Fisica ed Astronomia, Universita degli Studi di Catania (Italy); Sabini, M.G. [A.O. Cannizzaro, Catania (Italy); Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Salamone, V.; Valastro, L.M. [A.O.U. Policlinico, Universita degli Studi di Catania (Italy); Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy)

    2007-10-15

    Proton therapy represents the most promising radiotherapy technique for external tumor treatments. At Laboratori Nazionali del Sud of the Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania (I), a proton therapy facility is active since March 2002 and 140 patients, mainly affected by choroidal and iris melanoma, have been successfully treated. Proton beams are characterized by higher dose gradients and linear energy transfer with respect to the conventional photon and electron beams, commonly used in medical centers for radiotherapy. In this paper, we report the experience gained in the characterization of different dosimetric systems, studied and/or developed during the last ten years in our proton therapy facility.

  11. Proton therapy detector studies under the experience gained at the CATANA facility

    Science.gov (United States)

    Cuttone, G.; Cirrone, G. A. P.; Di Rosa, F.; Lojacono, P. A.; Lo Nigro, S.; Marino, C.; Mongelli, V.; Patti, I. V.; Pittera, S.; Raffaele, L.; Russo, G.; Sabini, M. G.; Salamone, V.; Valastro, L. M.

    2007-10-01

    Proton therapy represents the most promising radiotherapy technique for external tumor treatments. At Laboratori Nazionali del Sud of the Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania (I), a proton therapy facility is active since March 2002 and 140 patients, mainly affected by choroidal and iris melanoma, have been successfully treated. Proton beams are characterized by higher dose gradients and linear energy transfer with respect to the conventional photon and electron beams, commonly used in medical centers for radiotherapy.In this paper, we report the experience gained in the characterization of different dosimetric systems, studied and/or developed during the last ten years in our proton therapy facility.

  12. Supporting deployed operations: are military nurses gaining the relevant experience from MDHUs to be competent in deployed operations?

    Science.gov (United States)

    Beaumont, Steven P; Allan, Helen T

    2014-01-01

    To explore how peacetime employment of military nurses in the UK National Health Service Medical Defence Hospital Units prepares them to be competent to practise in their role on deployment. Military secondary care nurses are employed within UK National Health Service Trusts to gain clinical experience that will be relevant to their military nursing role. A two-stage grounded theory study using mixed methods: postal questionnaire survey and in-depth interviews. In stage one a postal questionnaire was distributed to all serving military nurses. Stage two involved 12 semi-structured interviews. The data from both parts of the study were analysed using grounded theory. Four categories and one core category were identified, which suggested that participants did not feel fully prepared for deployment. Their feelings of preparedness increased with deployment experience and decreased when the nature of injuries seen on deployment changed. Respondents argued that even when unprepared, they did not feel incompetent. The findings suggest that the peacetime clinical experience gained in the National Health Service did not always develop the necessary competencies to carry out roles as military nurses on deployment. This study highlights the unique role of military nurses. We discuss these findings in the light of the literature on competency and expertise. The military nurses in this study did not feel fully prepared for deployed operations. We propose a new model for how military nurses could gain relevant experience from their National Health Service placements. National Health Service clinical placements need to be reassessed regularly to ensure that they are meeting military nurses' clinical requirements. Experiences of nurses returning from deployment could be shared and used as a basis for reflection and learning within National Health Service Trusts and also inform decisions regarding the appropriateness of clinical placements for qualified military nurses. © 2012

  13. Material science experience gained from the space nuclear rocket program: Insulators

    International Nuclear Information System (INIS)

    Wagner, P.

    1992-07-01

    Although Rover reactors are viewed as the ultimate in high-temperature operating systems, many of the materials used in these reactors (for example, support rods, control drums, and the reflector) have to be held at relatively low temperatures while the reactor operates, in order to maintain their structural integrity. Thus the insulators needed to separate these temperature domains are crucial to the reactor's ultimate operating times and temperatures. All of the reactors that were tested used pyrolytic graphite as the primary insulator. However, it had been long planned to replace the graphite with zirconium carbide and a lengthy and intensive effort to develop the zirconium carbide insulators had been made at the time Rover was terminated. This report details research and development and the experience we gained with both these insulator materials

  14. Learning Experiences and Gains from Continuing Professional Education and Their Applicability to Work for Japanese Government Officials

    Science.gov (United States)

    Noda, Ayaka; Kim, Mikyong Minsun

    2014-01-01

    This study aims to understand the perceived learning experiences and gains for Japanese government officials from US and Japanese graduate and professional schools, and how applicable their continuing professional education (CPE) is to professional performance. Interview participants were drawn from long-term overseas and domestic fellowship…

  15. The present state of the HTR concept based on experience gained from AVR and THTR

    International Nuclear Information System (INIS)

    Wachholz, W.

    1989-01-01

    During the past ten years the development of a specific HTR concept has made remarkable progress. This has been mainly characterized by making use of the safety characteristics typical of the High-Temperature Reactor (HTR). In the design, construction and operation of High-Temperature Reactors - especially AVR (15 MWe plant in Juelich, FRG) and THTR (300 MWe plant in Hamm-Uentrop, FRG) - comprehensive experience has been gained in the field of operational availability and safety, accident topology and plant risk of HTRs in recent years. This experience is relevant for the entire HTR line independent of specific projects. (author). 3 refs, 5 figs, 1 tab

  16. Rapid weight gain in professional boxing and correlation with fight decisions: analysis from 71 title fights.

    Science.gov (United States)

    Daniele, Gianlorenzo; Weinstein, Richard N; Wallace, Paul Wesley; Palmieri, Vincenzo; Bianco, Massimiliano

    2016-11-01

    Boxing is a sport where athletes compete in several weight categories. Professional boxers typically dehydrate to cut their weight for the weigh-in (24 h before the contest) and then rehydrate before the fight. The International Boxing Federation (IBF) mandates a second weigh-in 12 h before the fight. Our objectives were: 1) To quantify the weight gain (WG) from the 1st to the 2nd weigh-in; 2) to investigate whether rapid WG affects boxing performance (win/loss rate) and 3) whether weight discrepancy (WD) 15 between boxers exposes them to increased health risks (rate of fights ended before time limit). From official weigh-in reports of 71 IBF fights (142 fighters) the following data were gathered/calculated for each boxer: age, weight division, 1st weight, 2nd weight, WG between weigh-ins (kg and %), WD between opponents, and fight decision. Between the weigh-ins, the average WG was 2.52 ± 1.37 kg (range -0.3/6.4 kg) and 3.8 ± 2.2% of the initial body weight (range -0.4/9.3%) and the average WD 1.94 ± 1.50 kg (maximum 7.10 kg). Both WG and WD did not affect match outcomes. We observed tendencies for higher loss rate among boxers gaining more weight, and for higher victory rate in boxers with larger WD, however without reaching significance. A significant negative correlation was found between the 1st weight and the WG, both in absolute (r = -0.278, p = 0.001) and relative value (r = -0.497, p boxing performance were not found, single cases with an alarming high WG and WD were noted.

  17. Can LENR Energy Gains Exceed 1000?

    Science.gov (United States)

    Nagel, David J.

    2011-03-01

    Energy gain is defined as the energy realized from reactions divided by the energy required to produce those reactions. Low Energy Nuclear Reactions (LENR) have already been measured to significantly exceed the energy gain of 10 projected from ITER,possibly 15 years from now. Electrochemical experiments using the Pd-D system have shown energy gains exceeding 10. Gas phase experiments with the Ni-H system were reported to yield energy gains of over 100. Neither of these reports has been adequately verified or reproduced. However, the question in the title still deserves consideration. If, as thought by many, it is possible to trigger nuclear reactions that yield MeV energies with chemical energies of the order of eV, then the most optimistic expectation is that LENR gains could approach one million. Hence, the very tentative answer to the question above is yes. However, if LENR could be initiated with some energy cost, and then continue to ``burn,'' very high energy gains might be realized. Consider a match and a pile of dry logs. The phenomenon termed ``heat after death'' will be examined to see if it might be the initial evidence for nuclear ``burning.''

  18. Rapid innovation diffusion in social networks.

    Science.gov (United States)

    Kreindler, Gabriel E; Young, H Peyton

    2014-07-22

    Social and technological innovations often spread through social networks as people respond to what their neighbors are doing. Previous research has identified specific network structures, such as local clustering, that promote rapid diffusion. Here we derive bounds that are independent of network structure and size, such that diffusion is fast whenever the payoff gain from the innovation is sufficiently high and the agents' responses are sufficiently noisy. We also provide a simple method for computing an upper bound on the expected time it takes for the innovation to become established in any finite network. For example, if agents choose log-linear responses to what their neighbors are doing, it takes on average less than 80 revision periods for the innovation to diffuse widely in any network, provided that the error rate is at least 5% and the payoff gain (relative to the status quo) is at least 150%. Qualitatively similar results hold for other smoothed best-response functions and populations that experience heterogeneous payoff shocks.

  19. Robust Optimal Adaptive Control Method with Large Adaptive Gain

    Science.gov (United States)

    Nguyen, Nhan T.

    2009-01-01

    In the presence of large uncertainties, a control system needs to be able to adapt rapidly to regain performance. Fast adaptation is referred to the implementation of adaptive control with a large adaptive gain to reduce the tracking error rapidly. However, a large adaptive gain can lead to high-frequency oscillations which can adversely affect robustness of an adaptive control law. A new adaptive control modification is presented that can achieve robust adaptation with a large adaptive gain without incurring high-frequency oscillations as with the standard model-reference adaptive control. The modification is based on the minimization of the Y2 norm of the tracking error, which is formulated as an optimal control problem. The optimality condition is used to derive the modification using the gradient method. The optimal control modification results in a stable adaptation and allows a large adaptive gain to be used for better tracking while providing sufficient stability robustness. Simulations were conducted for a damaged generic transport aircraft with both standard adaptive control and the adaptive optimal control modification technique. The results demonstrate the effectiveness of the proposed modification in tracking a reference model while maintaining a sufficient time delay margin.

  20. Monitoring of radioactivity in imported foodstuffs - experience gained and recommendations

    International Nuclear Information System (INIS)

    Abdul-Fattah, A.F.; Mamoon, A.M.; Abdul-Majid, S.

    1987-01-01

    Saudi Arabia has had a unique experience in radiation monitoring of imported foodstuffs for possible contamination due to the Chernobyl reactor accident. A considerable amount of various food items is imported by Saudi Arabia and much of it comes from European countries. The quantity of imported food items is greatly increased around the time of the Moslem pilgrimage to Holy Mecca. Furthermore, many additional thousands of live animals (mainly sheep and cows) are imported for sacrificing on a certain day for religious reasons. The radiation monitoring of food items at inlets to the county was not done before and a lot of preparatory work and planning had to be done to initiate the monitoring process. The experience gained in this respect might be of value to other developing countries in a similar position. King Abdulaziz Univ. (KAU) was directed by the government in about mid-June 1986 to carry out radiological inspection of food items reaching the Jeddah, Yanbu, and Jizan seaports as well as food arrivals at King Abdulaziz International Airport at Jeddah. The KAU team has met with some difficulties in carrying out its inspection responsibilities. These difficulties are of a general nature and might occur, in a similar inspection process, in other developing countries. The problems can be classified essentially into the two categories discussed: (1) problems of an administrative and management nature, and (2) problems of a technical nature

  1. Cleavings: Critical Losses in the Politics of Gain

    Directory of Open Access Journals (Sweden)

    Michael Davidson

    2016-05-01

    Full Text Available Many of Emily Dickinson's best known poems deal with the loss of sight, based on her own experiences with temporary blindness in the mid 1860s, but they are less about the absence of sight than about how she experiences the limits of consciousness: "I could not see to see." She probed the loss of sensation for what it could teach her about what is most familiar—and thus invisible. Using poems by Emily Dickinson and recent work in cultural and queer theory, this essay explores the fine line between "gain" and "loss" in disability studies. Using the author's experience of sudden hearing loss, "Cleavings" argues that recent claims for "deaf gain" have vaunted possibilities of cultural inclusiveness to the exclusion of affective realms of frustration, loss, and failure that are seldom acknowledged experiences of deaf and hard-of-hearing persons. While endorsing the general thrust of deaf gain and its implications for the larger context of disability, "Cleavings" argues for a more critical understanding of loss in the politics of gain.

  2. Gains and losses of exclusivity in grocery retailing

    NARCIS (Netherlands)

    Gielens, K.J.P.; Gijsbrechts, E.; Dekimpe, M.G.

    Conventional wisdom dictates that convenience goods should be distributed as intensively as possible. Still, exclusivity arrangements are rapidly gaining way in grocery retailing. We discuss the possible performance outcomes of exclusivity deals, and propose a unified framework (i) to quantify the

  3. Maternal smoking during pregnancy and rapid weight gain from birth to early infancy

    Directory of Open Access Journals (Sweden)

    Tomosa Mine

    2017-04-01

    Full Text Available Background: Although several studies have focused on the association between maternal smoking during pregnancy and rapid weight gain (RWG during infancy, the dose-response relationship has not yet been confirmed, and very few studies have included Asian populations. Using a record-linkage method, we examined the association between maternal smoking during pregnancy and RWG in infants at around 4 months of age to clarify the dose-response relationship. Methods: Two databases were used: maternal check-ups during pregnancy and early infancy check-ups (between April 1, 2013 and March 31, 2014 in Okinawa, Japan were linked via IDs and provided to us after unlinkable anonymizing. For 10,433 subjects (5229 boys and 5204 girls, we calculated the change in infants' weight z-score by subtracting the z-score of their birth weight from their weight at early infancy check-ups. Smoking exposure was categorized into five groups. We used Poisson regression to examine the association of maternal smoking during pregnancy with RWG in early infancy. Results: Overall, 1524 (14.6% were ex-smoker and 511 (4.9% were current smoker. Compared with the reference category of non-smokers, the adjusted risk ratio of RWG was 1.18 (95% confidence interval [CI], 1.06–1.32 for ex-smokers, 1.18 (95% CI, 0.93–1.50 for those who smoked 1–5 cigarettes per day, 1.57 (95% CI, 1.24–2.00 for those who smoked 6–10 cigarettes per day, and 2.13 (95% CI, 1.51–3.01 for those who smoked ≥11 cigarettes per day. There was a clear dose-response relationship. Conclusion: Our study suggests that maternal smoking during pregnancy is associated in a dosedependent manner with increased risk of RWG in early infancy.

  4. Intrinsic gain modulation and adaptive neural coding.

    Directory of Open Access Journals (Sweden)

    Sungho Hong

    2008-07-01

    Full Text Available In many cases, the computation of a neural system can be reduced to a receptive field, or a set of linear filters, and a thresholding function, or gain curve, which determines the firing probability; this is known as a linear/nonlinear model. In some forms of sensory adaptation, these linear filters and gain curve adjust very rapidly to changes in the variance of a randomly varying driving input. An apparently similar but previously unrelated issue is the observation of gain control by background noise in cortical neurons: the slope of the firing rate versus current (f-I curve changes with the variance of background random input. Here, we show a direct correspondence between these two observations by relating variance-dependent changes in the gain of f-I curves to characteristics of the changing empirical linear/nonlinear model obtained by sampling. In the case that the underlying system is fixed, we derive relationships relating the change of the gain with respect to both mean and variance with the receptive fields derived from reverse correlation on a white noise stimulus. Using two conductance-based model neurons that display distinct gain modulation properties through a simple change in parameters, we show that coding properties of both these models quantitatively satisfy the predicted relationships. Our results describe how both variance-dependent gain modulation and adaptive neural computation result from intrinsic nonlinearity.

  5. Rapid-Growing Mycobacteria Infections in Medical Tourists: Our Experience and Literature Review.

    Science.gov (United States)

    Singh, Mansher; Dugdale, Caitlin M; Solomon, Isaac H; Huang, Anne; Montgomery, Mary W; Pomahac, Bohdan; Yawetz, Sigal; Maguire, James H; Talbot, Simon G

    2016-09-01

    "Medical tourism" has gained popularity over the past few decades. This is particularly common with patients seeking elective cosmetic surgery in the developing world. However, the risk of severe and unusual infectious complications appears to be higher than for patients undergoing similar procedures in the United States. The authors describe their experience with atypical mycobacterial infections in cosmetic surgical patients returning to the United States postoperatively. A review of patient medical records presenting with infectious complications after cosmetic surgery between January 2010 and July 2015 was performed. Patients presenting with mycobacterial infections following cosmetic surgery were reviewed in detail. An extensive literature review was performed for rapid-growing mycobacteria (RGM) related to cosmetic procedures. Between January 2010 and July 2015, three patients presented to our institution with culture-proven Mycobacterium abscessus at the sites of recent cosmetic surgery. All had surgery performed in the developing world. The mean age of these patients was 36 years (range, 29-44 years). There was a delay of up to 16 weeks between the initial presentation and correct diagnosis. All patients were treated with surgical drainage and combination antibiotics with complete resolution. We present series of patients with mycobacterial infections after cosmetic surgery in the developing world. This may be related to the endemic nature of these bacteria and/or inadequate sterilization or sterile technique. Due to low domestic incidence of these infections, diagnosis may be difficult and/or delayed. Consulting physicians should have a low threshold to consider atypical etiologies in such scenarios. 5 Therapeutic. © 2016 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com.

  6. Gaining environmental resource consents: a New Zealand experience

    International Nuclear Information System (INIS)

    Hopkins, K.N.; Pritchard, N.E.

    1995-01-01

    In 1991 the Electricity Corporation of New Zealand was faced with the renewal of existing permits and rights under the requirements of the newly-passed Resource Management Act. Specifically for Huntly Power Station a strategy was required to ensure new Consents were gained to replace Water Rights and a Clean Air Act Licence due to expire in 1994. Key aspects of the Act are environmental protection, a requirement to consider Maori cultural concerns, and the need for a public participation stage in the Consents process. This paper documents aspects of the work completed to ensure Huntly gained its new Air and Water Resource Consents and indicates follow-up work in progress. Most attention in the water area focused on the discharge of condenser cooling water into the Waikato River with studies on fish health, migration and breeding habits being carried out. A novel solution involving the installation of 'Iowa Vanes' in the river has been decided on to optimize effective mixing of the cooling water with the river channel in front of the Station and thus minimize the effect of warm water entering the river. (author). 3 figs., 3 refs

  7. Experience gained at the NEA Data Bank with a commercial data base management system

    International Nuclear Information System (INIS)

    Johnson, D.; Pellegrino, L.; Schuler, W.; Tubbs, N.

    1981-01-01

    The Nuclear Energy Agency Data Bank of the OECD has recently converted the computer storage of large numerical and bibliographic files to a commecial data base management system (DBMS). Such systems are relatively new in scientific use, but they are well-developed and are widely applied in commercial and industrial environments. This application is of particular interest in that it involves scientific information and the size of the data approaches what is feasible with a DBMS on a small computer. In this paper, the experience gained throughout the project is documented for the benefit of others who way be contemplating a similar application. Some of the points considered with be specific to this actual base and to the system used, but the paper also contains much information of general interest. Our viewpoint is that of applications software developers with limited previous DBMS experience and the emphasis is on the practical details of establishing a CODASYL-type data base

  8. Initial experience gained with the balance-group system of the Swiss power supply legislation

    International Nuclear Information System (INIS)

    Waldner, M.; Rechsteiner, S.

    2010-01-01

    This article takes a look at the initial experience gained with the Swiss balance-group system. This system was introduced within the framework of Swiss power supply legislation (StromVG - Stromversorgungsgesetz). The balance-group system was considered to be an essential precondition for the implementation of an energy trading business in a liberalised power market. The associated rights and responsibilities and the economic risks involved are discussed in detail. The partners and structures involved in such a balance-group are looked at and basic models for the associated contracts are examined. The relationship between balance-groups and the national power grid Swissgrid are discussed

  9. Experience gained with Euratom's nuclear materials accounting and reporting system

    International Nuclear Information System (INIS)

    Schmitt, M.; Kschwendt, H.; Maxwell, A.G.; Littlejohn, M.

    1979-01-01

    The entry into force of the Verification Agreement in early 1977, linked to the wish to update the old Euratom System created in 1959, required that a new Euratom system (Community Regulation) be established. The main aspects of this new system, together with the practical experience gained in one and a half years operation, are presented. Certain basic accounting principles incorporated in the Euratom system, which are somewhat different from IAEA principles, are discussed in detail. This includes the notion of accounting date, some correction procedure aspects as well as the continuous updating of the book inventory to the physical reality in form of inventory changes. The effect of these differences when comparing IAEA and Euratom data is also mentioned. Furthermore, certain of the verifications carried out routinely on the operator's reports as well as on the reports submitted by Euratom to IAEA, are described and quantifications are given. Some mention is also made of areas where Euratom's role goes beyond that of the IAEA, i.e. the reporting implications of accounting for material by origin and control of particular use of the materials as well as verification of ore production and processing activities. Finally, improvements and simplifications concerning reports to the IAEA are proposed. (author)

  10. Gaining hope and self-confidence-An interview study of women's experience of treatment by art therapy for severe fear of childbirth.

    Science.gov (United States)

    Wahlbeck, Helén; Kvist, Linda J; Landgren, Kajsa

    2017-10-31

    Fear of childbirth is a serious problem that can have negative effects on both women and babies and to date treatment options are limited. The aim of this study was to elucidate the experience of undergoing art therapy in women with severe fear of childbirth. Nineteen women residing in Sweden, who had undergone art therapy for severe fear of childbirth, were interviewed during 2011-2013 about their experiences of the treatment. All women had received both support from a specialist team of midwives and treatment by an art therapist who was also a midwife. The women were interviewed three months after giving birth. The transcribed interviews were analysed with a phenomenological hermeneutical method. A main theme and three themes emerged from the analysis. The main theme was Gaining hope and self confidence. The three themes were; Carrying heavy baggage, Creating images as a catalyst for healing and Gaining new insights and abilities. Through the use of images and colours the women gained access to difficult emotions and the act of painting helped them visualize these emotions and acted as a catalyst for the healing process. Art therapy was well accepted by the women. Through sharing their burden of fear by creating visible images, they gained hope and self-confidence in the face of their impending childbirth. The results may contribute to knowledge about the feasibility of treating fear of childbirth by art therapy. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. Clad failure detection in G 3 - operational feedback; Detection de rupture de gaines G 3 - experience d'exploitation

    Energy Technology Data Exchange (ETDEWEB)

    Plisson, J [CEA Marcoule, Centre de Production de Plutonium, 30 (France)

    1964-07-01

    After briefly reviewing the role and the principles of clad failure detection, the author describes the working conditions and the conclusions reached after 4 years operation of this installation on the reactor G 3. He mentions also the modifications made to the original installation as well as the tests carried out and the experiments under way. (author) [French] Apres un rappel succinct du role et des principes de la detection de rupture de gaines, l'auteur fait un expose des conditions de fonctionnement et de l'experience tiree de 4 annees d'exploitation de cette installation sur le reacteur G 3. Il signale au passage les modifications apportees a l'installation d'origine, ainsi que les essais effectues, et les experiences en cours.

  12. Faculty experiences with rapid integration of male nursing students within a patriarchal societal context.

    Science.gov (United States)

    Kulakac, Ozen; Arslan, Ilkay; Sucu Dag, Gülten; O'Lynn, Chad

    2015-11-01

    In 2007, reforms by the Turkish government forced a rapid integration of male nursing students into previously all-female schools. The minimal amount of time for faculty preparation, little guidance from nursing leaders and the extant literature, and a societal context of patriarchy created unique challenges for faculty. The purpose of this qualitative study was to explore and interpret the experiences of nursing faculty as they adapted to the sudden inclusion of men in schools of nursing. A qualitative descriptive study Nine schools from six regions across Turkey 99 nursing faculty who were 22 to 55years of age, primarily female (97.8%), married (65.6%). Focus groups were used to collect data. Data were analyzed using constant comparison and tripartite discussion. Analysis yielded three categories, seven themes, and seven subthemes describing variable experiences, perceptions, and adaptive strategies. The findings presented contradictions characterized by both optimism and concern following the rapid infusion of men into schools of nursing. Concerns primarily centered on the state of gender relations in a larger patriarchal society. The findings foster reflection and discourse as societies characterized by relatively rigid and traditional gender roles confront rapid cultural change and growing calls for diversity within nursing. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Characterization of transient gain x-ray lasers

    International Nuclear Information System (INIS)

    Dunn, J.; Osterheld, A.; Shlyaptsev, V.

    1999-01-01

    We have performed numerical simulations of the transient collisional excitation Ni-like Pd 4d → 4p J = 0 → 1 147 angstrom laser transition recently observed at Lawrence Livermore National Laboratory (LLNL). The high gain ∼35 cm results from the experiment are compared with detailed modeling simulations from the 1-D RADEX code in order to better understand the main physics issues affecting the measured gain and x-ray laser propagation along the plasma column. Simulations indicate that the transient gain lifetime associated with the short pulse pumping and refraction of the x-ray laser beam out of the gain region are the main detrimental effects. Gain lifetimes of ∼7 ps(1/e decay) are inferred from the smoothly changing gain experimental observations and are in good agreement with the simulations. Furthermore, the modeling results indicate the presence of a longer-lived but lower gain later in time associated with the transition from transient to quasi-steady state excitation

  14. Improving the user experience through practical data analytics gain meaningful insight and increase your bottom line

    CERN Document Server

    Fritz, Mike

    2015-01-01

    Improving the User Experience through Practical Data Analytics is your must-have resource for making UX design decisions based on data, rather than hunches. Authors Fritz and Berger help the UX professional recognize and understand the enormous potential of the ever-increasing user data that is often accumulated as a by-product of routine UX tasks, such as conducting usability tests, launching surveys, or reviewing clickstream information. Then, step-by-step, they explain how to utilize both descriptive and predictive statistical techniques to gain meaningful insight with that data. You'll be

  15. Dynamic excitatory and inhibitory gain modulation can produce flexible, robust and optimal decision-making.

    Directory of Open Access Journals (Sweden)

    Ritwik K Niyogi

    Full Text Available Behavioural and neurophysiological studies in primates have increasingly shown the involvement of urgency signals during the temporal integration of sensory evidence in perceptual decision-making. Neuronal correlates of such signals have been found in the parietal cortex, and in separate studies, demonstrated attention-induced gain modulation of both excitatory and inhibitory neurons. Although previous computational models of decision-making have incorporated gain modulation, their abstract forms do not permit an understanding of the contribution of inhibitory gain modulation. Thus, the effects of co-modulating both excitatory and inhibitory neuronal gains on decision-making dynamics and behavioural performance remain unclear. In this work, we incorporate time-dependent co-modulation of the gains of both excitatory and inhibitory neurons into our previous biologically based decision circuit model. We base our computational study in the context of two classic motion-discrimination tasks performed in animals. Our model shows that by simultaneously increasing the gains of both excitatory and inhibitory neurons, a variety of the observed dynamic neuronal firing activities can be replicated. In particular, the model can exhibit winner-take-all decision-making behaviour with higher firing rates and within a significantly more robust model parameter range. It also exhibits short-tailed reaction time distributions even when operating near a dynamical bifurcation point. The model further shows that neuronal gain modulation can compensate for weaker recurrent excitation in a decision neural circuit, and support decision formation and storage. Higher neuronal gain is also suggested in the more cognitively demanding reaction time than in the fixed delay version of the task. Using the exact temporal delays from the animal experiments, fast recruitment of gain co-modulation is shown to maximize reward rate, with a timescale that is surprisingly near the

  16. Containment integrity and leak testing. Procedures applied and experiences gained in European countries

    International Nuclear Information System (INIS)

    1987-01-01

    Containment systems are the ultimate safety barrier for preventing the escape of gaseous, liquid and solid radioactive materials produced in normal operation, not retained in process systems, and for keeping back radioactive materials released by system malfunction or equipment failure. A primary element of the containment shell is therefore its leak-tight design. The report describes the present containment concepts mostly used in European countries. The leak-testing procedures applied and the experiences gained in their application are also discussed. The report refers more particularly to pre-operational testing, periodic testing and extrapolation methods of leak rates measured at test conditions to expected leak rates at calculated accident conditions. The actual problems in periodic containment leak rate testing are critically reviewed. In the appendix to the report a summary is given of the regulations and specifications applied in different member countries

  17. The Impact of Sudden Gains in Cognitive Behavioral Therapy for Posttraumatic Stress Disorder

    Science.gov (United States)

    Kelly, Kacie A.; Rizvi, Shireen L.; Monson, Candice M.; Resick, Patricia A.

    2009-01-01

    This study investigated sudden gains, i.e., rapid and stable improvements, in posttraumatic stress disorder (PTSD) symptoms that may occur in cognitive–behavioral therapy. Twenty-nine of 72 participants (39.2%) experienced a sudden gain during treatment. Mixed model ANOVAs analyzed sudden gains impact on clinician-rated PTSD symptom severity, patient-rated PTSD symptom severity, and patient-rated depressive symptom severity. Sudden gains in PTSD symptomology were associated with greater reductions in PTSD symptom severity for the avoidance/numbing and hyperarousal symptom clusters at posttreatment. By 6-month follow-up, the sudden gains group had maintained those reductions in symptoms, but the nonsudden gains group had achieved equal reductions in symptom severity. Participants experiencing sudden gains on PTSD measures had lower depression severity at posttreatment and follow-up. PMID:19637322

  18. Experience gained in running the EPRI MMS code with an in-house simulation language

    International Nuclear Information System (INIS)

    Weber, D.S.

    1987-01-01

    The EPRI Modular Modeling System (MMS) code represents a collection of component models and a steam/water properties package. This code has undergone extensive verification and validation testing. Currently, the code requires a commercially available simulation language to run. The Philadelphia Electric Company (PECO) has been modeling power plant systems for over the past sixteen years. As a result, an extensive number of models have been developed. In addition, an extensive amount of experience has been developed and gained using an in-house simulation language. The objective of this study was to explore the possibility of developing an MMS pre-processor which would allow the use of the MMS package with other simulation languages such as the PECO in-house simulation language

  19. Receiver gain function: the actual NMR receiver gain

    OpenAIRE

    Mo, Huaping; Harwood, John S.; Raftery, Daniel

    2010-01-01

    The observed NMR signal size depends on the receiver gain parameter. We propose a receiver gain function to characterize how much the raw FID is amplified by the receiver as a function of the receiver gain setting. Although the receiver is linear for a fixed gain setting, the actual gain of the receiver may differ from what the gain setting suggests. Nevertheless, for a given receiver, we demonstrate that the receiver gain function can be calibrated. Such a calibration enables accurate compar...

  20. Experience gained in gamma spectroscopy

    International Nuclear Information System (INIS)

    Jeanmaire, L.

    1960-01-01

    There are two types of method which make it possible to estimate the internal contamination of individuals. On the one hand these are the indirect techniques based on measurements of the excreted products, on the other there are the direct techniques in which attempts are made to measure directly the radio-activity existing in the organism. We propose to give a few of the results obtained by the direct method using equipment built by the Commissariat a l'Energie Atomique. The apparatus consists of a γ spectrometer. It includes: 1) A crystal of sodium iodide 20 cm in diameter and 10 cm high. The large size of this crystal ensures a good sensitivity and makes it possible to carry out rapid measurements. 2) A 25 channel type SAE 25 selector which classifies the pulses according to their amplitude. It is therefore possible to distinguish between γ rays of varying energy. 3) A comparatively very light radiation protection, consisting of only 5 cm thickness of lead which diminishes the ambient γ ray intensity to a sufficient level for the majority of the measurements. A certain collimation is thus obtained which makes it possible to localise the source approximately and to reduce the undesirable effects of external contamination. (author) [fr

  1. Gained experiences concerning the treatment of radioactive metal scrap from German NPP'S in Studsvik - Gained experience concerning the treatment of radioactive metal scrap from German nuclear power plants

    International Nuclear Information System (INIS)

    Westerwinter, Boris; Buckanie, Niemma

    2014-01-01

    The company Gesellschaft fuer Nuklear-Service mbH, Essen/Germany (GNS), operates on behalf of the utilities E.ON, RWE, EnBW and VENE since the nineteen-nineties - amongst its other duties - on the waste management of metal scrap which originates from German nuclear power plants. The main objective within this responsibility is to maximize the value of recyclable fractions for re-use while minimizing the resulting radioactive waste. To achieve the aforementioned objective, melting of metallic scrap proved to be an outstanding choice. The use of this technique combined with all accompanying processes and regulations is accepted by the competent authorities and independent experts as a qualified treatment method over the entire time period. The motivation of this paper is to reflect on the experiences gained concerning the planning, implementation and results, acquired by GNS by using the Studsvik service. The focus will be on characteristics within processing of such campaigns. (authors)

  2. The narrative structure as a way to gain insight into peoples' experiences: one methodological approach.

    Science.gov (United States)

    Rejnö, Åsa; Berg, Linda; Danielson, Ella

    2014-09-01

    The narrative method is used in healthcare research, mostly in data collection but also in the analysis. Narrative approaches draw attention to how people tell about and create meaning of experiences. The aim of the article was to examine the narrative structure, the elements in the structure and their function and how these can be used in research to gain insights into experiences. Examples are taken from a material of narratives from a study where next of kin were asked to narrate their experiences of sudden and unexpected death from stroke. The narratives had a clear beginning, midpoint and ending. In the beginning, orientation of the narrated events was given. The narrated events were told to have a turning point constituted of complicating actions that lead to a resolution that solved the narrated event. The narratives were built up by multiple recaps into the narrated events and also consisted of asides - side narratives and flashbacks - events back in time. Use of a narrative structure can contribute with valuable information that might be missed with other analysis. The analysis can be used on its own, as a complement to other narrative analysis or even as a complement to other qualitative analysis. © 2013 Nordic College of Caring Science.

  3. Subpicosecond gain dynamics in GaAlAs laser diodes

    Energy Technology Data Exchange (ETDEWEB)

    Kesler, M.P.; Ippen, E.P.

    1987-11-30

    Ultrafast gain dynamics in GaAlAs diode amplifiers have been studied using 100 fs optical pulses. Pulse propagation through the amplifier resulted in temporal broadening and pulse shaping due to both gain saturation and material dispersion. Pump-probe experiments indicate the presence of two processes contributing to the gain dynamics but give no evidence of spectral hole burning. A dynamic carrier heating model is presented to explain all of the observed gain nonlinearities, and the implications of our results on the dynamic response of laser diodes are discussed.

  4. Computerisation of general practice in the Republic of Croatia: experience gained in general practice use

    Directory of Open Access Journals (Sweden)

    Biserka Bergman-Markovi_

    2007-09-01

    Full Text Available Well-organised medical records are the prerequisite for achieving a high level of performance in primary healthcare settings. Recording balanced structured and coded data as well as free text can improve both quality and organisation of work in the office. It provides a more substantiated support of financial transactions and accountancy, allows better communication with other facilities and institutions, and is a source of valuable scientific research material. This article is the result of an individual experience gained in general practice use of various programs/ systems employed within the family medicine frame, and the frame of evaluation of available and commonly- exploited program solutions. The use of various programs allows for systematic adjustments as to the increasingly complex requirements imposed on electronic medical records (EMRs. The experience of a general practitioner, presented in this paper, confirms the assumption that an adequate program to be employed with EMRs should be developed, provided that family medicine practitioners, that is, the final users, have been involved in each and every stage of its development, adjustment, implementation and evaluation.

  5. Low Birthweight, Rapid Weight Gain and Metabolic Syndrome in Adolescence: An Illustrative Case Report

    Directory of Open Access Journals (Sweden)

    Onyiriuka Alphonsus N.

    2015-12-01

    Full Text Available A 16-year-old boy whose diabetes mellitus was diagnosed 3 months previously in a private hospital but was not placed on medication. The presenting complaints were fast breathing for 24 hours, weakness for 2 hours, and unresponsiveness to calls for 0.5 hours. His father was obese with type 2 diabetes mellitus and died 8 months earlier from cardiac arrest. His birthweight was low, 2.2kg. At first presentation, his weight, BMI and blood pressure were 60kg (25th-50th percentile, 19.4kg/m2 (25thpercentile and 110/70mmHg (systolic BP 50th percentile, diastolic BP 50th-90th percentile, respectively. He was managed for diabetic ketoacidosis and was discharged on subcutaneous premixed insulin, 1 Unit/kg/day. At point of discharge, weight and BP were 60.5 kg and 120/70 mmHg, respectively. The patient defaulted but presented again 6 months later at the age of 17 years. At second presentation, his weight, BMI and BP were 89 kg (95th percentile, 27.5 kg/m2 (90th-95th percentile and 180/80 mmHg (systolic 99th percentile; diastolic 90th percentile, respectively. His waist circumference was 98.7cm (> 90th percentile. We had no record of previous waist circumference. His lipid profile showed low HDL-cholesterol 0.7252 mmol/L [(28mg/dl; <5thpercentile]. His fasting blood glucose and HbA1C were 6.5 mmol/L (117mg/dl and 34 mol/mol (5.3%, respectively. A diagnosis of metabolic syndrome in a patient with ketosis-prone type 2 diabetes was made. He was referred to the pediatric cardiologist for management of his hypertension. He defaulted again and was lost to follow up. Conclusion: This report illustrates the association of low birth weight and rapid weight gain with metabolic syndrome in adolescence.

  6. NMR experiments for the rapid identification of P=O···H-X type hydrogen bonds in nucleic acids.

    Science.gov (United States)

    Duchardt-Ferner, Elke; Wöhnert, Jens

    2017-10-01

    Hydrogen bonds involving the backbone phosphate groups occur with high frequency in functional RNA molecules. They are often found in well-characterized tertiary structural motifs presenting powerful probes for the rapid identification of these motifs for structure elucidation purposes. We have shown recently that stable hydrogen bonds to the phosphate backbone can in principle be detected by relatively simple NMR-experiments, providing the identity of both the donor hydrogen and the acceptor phosphorous within the same experiment (Duchardt-Ferner et al., Angew Chem Int Ed Engl 50:7927-7930, 2011). However, for imino and hydroxyl hydrogen bond donor groups rapidly exchanging with the solvent as well as amino groups broadened by conformational exchange experimental sensitivity is severely hampered by extensive line broadening. Here, we present improved methods for the rapid identification of hydrogen bonds to phosphate groups in nucleic acids by NMR. The introduction of the SOFAST technique into 1 H, 31 P-correlation experiments as well as a BEST-HNP experiment exploiting 3h J N,P rather than 2h J H,P coupling constants enables the rapid and sensitive identification of these hydrogen bonds in RNA. The experiments are applicable for larger RNAs (up to ~ 100-nt), for donor groups influenced by conformational exchange processes such as amino groups and for hydrogen bonds with rather labile hydrogens such as 2'-OH groups as well as for moderate sample concentrations. Interestingly, the size of the through-hydrogen bond scalar coupling constants depends not only on the type of the donor group but also on the structural context. The largest coupling constants were measured for hydrogen bonds involving the imino groups of protonated cytosine nucleotides as donors.

  7. IAEA Safeguards: Present status and experience gained

    International Nuclear Information System (INIS)

    Thorne, L.; Buechler, C.; Haegglund, E.

    1983-01-01

    IAEA safeguards are at the present under critical review with regard to their purpose and effectiveness. This paper describes the development of the IAEA Safeguards System from the early days, when procedures were developed on an ad hoc basis, to the present day. The development of State Systems of Accounting for and Control of Nuclear Material (SSAC), and of sophisticated instrumentation, has been necessary to deal with the rapid growth in the quantities of nuclear material and in the number of facilities under safeguards. The paper also discusses some of the managerial and organizational issues that are inherent in such a large international inspectorate. (author)

  8. Experience gained during 10 years transmutation experiments in Dubna

    Science.gov (United States)

    Zamani, M.; Fragopoulou, M.; Manolopoulou, M.; Stoulos, S.; Brandt, R.; Westmeier, W.; Krivopustov, M.; Sosnin, A.; Golovatyuk, S.

    2006-05-01

    Transmutation, the procedure of transforming long-lived radioactive isotopes into stable or short-lived, was proposed for reducing the amount of radioactive waste resulting from technological applications of nuclear fission. The Accelerator Driven Systems (ADS) provide the possibility to generate intense neutron spectrum yielding in an effective transmutation of unwanted isotopes. Such experiments are being carried out for the last 10 years in Synchrophasotron / Nuclotron accelerators at the Veksler-Baldin Laboratory of High Energies of the Joint Institute for Nuclear Research in Dubna, Russia. Thick Pb and Pb-U targets, surrounded by moderators, have been irradiated by protons in the energy range of 0.5-7.4 GeV. Neutron fluence measurements have been performed by different techniques of passive detectors (neutron activation detectors, solid state nuclear track detectors). Transmutation of 129I, 237Np, 239Pu was studied. The results of these experiments are presented and discussed.

  9. Gasoline surrogate modeling of gasoline ignition in a rapid compression machine and comparison to experiments

    Energy Technology Data Exchange (ETDEWEB)

    Mehl, M; Kukkadapu, G; Kumar, K; Sarathy, S M; Pitz, W J; Sung, S J

    2011-09-15

    The use of gasoline in homogeneous charge compression ignition engines (HCCI) and in duel fuel diesel - gasoline engines, has increased the need to understand its compression ignition processes under engine-like conditions. These processes need to be studied under well-controlled conditions in order to quantify low temperature heat release and to provide fundamental validation data for chemical kinetic models. With this in mind, an experimental campaign has been undertaken in a rapid compression machine (RCM) to measure the ignition of gasoline mixtures over a wide range of compression temperatures and for different compression pressures. By measuring the pressure history during ignition, information on the first stage ignition (when observed) and second stage ignition are captured along with information on the phasing of the heat release. Heat release processes during ignition are important because gasoline is known to exhibit low temperature heat release, intermediate temperature heat release and high temperature heat release. In an HCCI engine, the occurrence of low-temperature and intermediate-temperature heat release can be exploited to obtain higher load operation and has become a topic of much interest for engine researchers. Consequently, it is important to understand these processes under well-controlled conditions. A four-component gasoline surrogate model (including n-heptane, iso-octane, toluene, and 2-pentene) has been developed to simulate real gasolines. An appropriate surrogate mixture of the four components has been developed to simulate the specific gasoline used in the RCM experiments. This chemical kinetic surrogate model was then used to simulate the RCM experimental results for real gasoline. The experimental and modeling results covered ultra-lean to stoichiometric mixtures, compressed temperatures of 640-950 K, and compression pressures of 20 and 40 bar. The agreement between the experiments and model is encouraging in terms of first

  10. Hard X-ray techniques suitable for polymer experiments

    Energy Technology Data Exchange (ETDEWEB)

    Bras, W; Goossens, H; Goderis, B, E-mail: Wim.Bras@esrf.fr [Netherlands Organisation for Scientific Research (NWO) (Netherlands); DUBBLE-ESRF, BP 220, F38043 Grenoble Cedex (France); Department of Chemical Engineering and Chemistry, Eindhoven University of Technology, PO Box 513, 5600 MB Eindhoven (Netherlands); Molecular and Nanomaterials, Chemistry Department, Catholic University of Leuven, Celestijnenlaan 200F (Belgium)

    2010-11-15

    Polymers have been studied since 1979 with 8-12 keV synchrotron radiation X-ray scattering methods and the number and sophistication of the experiments have rapidly grown ever since. More recently, new experimental techniques have been developed that use softer or harder X-rays in less conventional ways. This article provides a brief overview of the possibilities of hard X-ray techniques and indicates some areas that might gain from further developments.

  11. Hard X-ray techniques suitable for polymer experiments

    International Nuclear Information System (INIS)

    Bras, W; Goossens, H; Goderis, B

    2010-01-01

    Polymers have been studied since 1979 with 8-12 keV synchrotron radiation X-ray scattering methods and the number and sophistication of the experiments have rapidly grown ever since. More recently, new experimental techniques have been developed that use softer or harder X-rays in less conventional ways. This article provides a brief overview of the possibilities of hard X-ray techniques and indicates some areas that might gain from further developments.

  12. Visually induced gains in pitch discrimination

    DEFF Research Database (Denmark)

    Møller, Cecilie; Højlund, Andreas; Bærentsen, Klaus B.

    2018-01-01

    Perception is fundamentally a multisensory experience. The principle of inverse effectiveness (PoIE) states how the multisensory gain is maximal when responses to the unisensory constituents of the stimuli are weak. It is one of the basic principles underlying multisensory processing of spatiotem...

  13. Phase and gain measurements in a distributed-loss cyclotron-resonance maser amplifier

    International Nuclear Information System (INIS)

    Kesar, Amit; Jerby, Eli

    2002-01-01

    The control of gain and phase delay in a cyclotron-resonance maser (CRM) amplifier is essential for a variety of applications. In this experiment, the gain and phase-delay variations are measured with respect to controlling parameters; the electron-beam current and the axial magnetic field. Following Chu et al. [Phys. Rev. Lett. 74, 1103 (1995)], the CRM amplifier comprises of a distributed-loss waveguide to enable high gain without oscillations. Our experiment yields an amplification up to 26 dB, and a phase-delay control range of 360 deg. In order to keep a fixed gain with the varying phase delay, the two controlling parameters (i.e., the solenoid field and the beam current) are operated together in a compensating mode. The experiment is conducted in a frequency of 7.3 GHz, with an electron beam of 18-kV voltage and 0.25-0.4-A current. The experimental results are compared with a theoretical model. Practical implementations of gain and phase control in CRM devices are discussed

  14. Computer simulation of gain fluctuations in proportional counters

    International Nuclear Information System (INIS)

    Demir, Nelgun; Tapan, . Ilhan

    2004-01-01

    A computer simulation code has been developed in order to examine the fluctuation in gas amplification in wire proportional counters which are common in detector applications in particle physics experiments. The magnitude of the variance in the gain dominates the statistical portion of the energy resolution. In order to compare simulation and experimental results, the gain and its variation has been calculated numerically for the well known Aleph Inner Tracking Detector geometry. The results show that the bias voltage has a strong influence on the variance in the gain. The simulation calculations are in good agreement with experimental results. (authors)

  15. Fast reactor operating experience gained in Russia: Analysis of anomalies and abnormal operation cases

    International Nuclear Information System (INIS)

    Ashurko, Y.M.; Baklushin, R.P.; Zagorulko, Y.I.; Ivanenko, V.N.; Matveyev, V.P.; Vasilyev, B.A.

    2000-01-01

    Review of various anomalous events and abnormal operation experience gained in the process of Russian fast reactors operation is given in the paper. The main information refers to the BN-600 demonstration reactor operation. Statistical data on sodium leaks and steam generator failures are presented, and sources of these events and countermeasures taken to avoid their appearance on the operating reactors as well as related changes made in the BN-800 reactor design are considered. In the paper, some features of impurities behaviour are considered in various modes of the BN-600 reactor operation. Information is given on the impurities ingress into the circuits, on abnormal situation emerged in the process of the BN-600 reactor operation and its probable cause. Information is presented on the event related to the increased torque of the BN-600 reactor central rotating column and repair works performed. (author)

  16. Learning from Educator Experiences in a Hawaiian School: Peak Professional Learning and A'O

    Science.gov (United States)

    Seto, Laurie U'ilani

    2016-01-01

    Due to rapid advancements in the world and shifting priorities at the school level, educators must keep abreast of current developments and how to continue to engage and challenge students in creative ways. This study examined the experiences 21 Kamehameha Schools educators indicated best support their professional learning to gain further…

  17. Feedback Loop Gains and Feedback Behavior (1996)

    DEFF Research Database (Denmark)

    Kampmann, Christian Erik

    2012-01-01

    Linking feedback loops and system behavior is part of the foundation of system dynamics, yet the lack of formal tools has so far prevented a systematic application of the concept, except for very simple systems. Having such tools at their disposal would be a great help to analysts in understanding...... large, complicated simulation models. The paper applies tools from graph theory formally linking individual feedback loop strengths to the system eigenvalues. The significance of a link or a loop gain and an eigenvalue can be expressed in the eigenvalue elasticity, i.e., the relative change...... of an eigenvalue resulting from a relative change in the gain. The elasticities of individual links and loops may be found through simple matrix operations on the linearized system. Even though the number of feedback loops can grow rapidly with system size, reaching astronomical proportions even for modest systems...

  18. A new reactor core monitoring system. First experience gained at the Dukovany NPP

    International Nuclear Information System (INIS)

    Pecka, M.; Svarny, J.; Kment, J.

    2001-01-01

    The article deals with methods of interpretation of in-core measurements that are based on the determination of the three-dimensional (3D) power distribution within the reactor core, discusses on-line mode calculations, and describes the results obtained during the trial operation of the new SCORPIO-VVER reactor core monitoring system. The principles of the method of determination of the fuel assembly subchannel parameters are outlined. Alternative methods of self-powered detector signal conversion to local power are given, and some results of their testing are presented. Emphasis is put on self-powered detectors supplied by the US firm IST, which were first deployed at the Dukovany NPP in 1998. The predictive function of the SCORPIO-VVER system, whose implementation was inspired by favourable experience gained on some PWR reactors (such as the products of the Halden reactor project at Ringhals and Sizewell B) were adapted to the specific needs of WWER-440 reactors. The main results of validation of the functions are described and presented in detail. (author)

  19. [原著]Effect of Meal-Timing on Body Weight Gain in Young Women

    OpenAIRE

    Wang, Ming-Fu; Huang, Sheng-Chi; Chung, Hei-Mei; Lo, Shuen-Fang; Haeno, Fumiyo; Nomura, Satomi; Ikemiyasiro, Midori; Shinjo, Sumie; Asato, Liu; Yamamoto, Shigeru; Department of Food and Nutrition, Providence University, Taichung, Taiwan; Research Center of Comprehensive Medicine. Faculty of Medicine, University of the Ryukyus, Okinawa, Japan

    1993-01-01

    This study was designed to find when to eat for better weight control. Five experiments of 10 days duration were done with 7 young women volunteers. The daily energy intake was 33 kcal/kg in all the experiments but the time or size of meals was different in each experiment. We observed that the later the time of dinner, the more the weight gain; breakfast did not have any effect on the weight gain and an evening snack before dinner prevented weight gain due to a late dinner. These results sug...

  20. Population inversion and gain measurements for soft x-ray-laser development in a magnetically confined plasma column

    International Nuclear Information System (INIS)

    Suckewer, S.; Skinner, C.H.; Voorhees, D.; Milchberg, H.; Keane, C.; Semet, A.

    1983-06-01

    We present population inversion and gain measurements from an experimental investigation of possibilities to obtain high gain and lasing action in the soft x-ray region. Our approach to soft x-ray-laser development is based on rapid plasma cooling after the laser pulse by radiation losses, leading to fast recombination and collisional cascade into upper excited levels of CVI, for example, while the lower excited levels depopulate rapidly by radiative transitions, thus creating population inversions and gain. A approx. = 0.5 kJ CO 2 laser was focused onto a target of solid carbon or teflon; or CO 2 , O 2 , Ne gas, and the resulting plasma confined in a 50 to 90 kG magnetic field. Spectroscopic diagnostics with absolute intensity calibration were used to measure level populations

  1. Use of Genomic Estimated Breeding Values Results in Rapid Genetic Gains for Drought Tolerance in Maize

    Directory of Open Access Journals (Sweden)

    B.S. Vivek

    2017-03-01

    Full Text Available More than 80% of the 19 million ha of maize ( L. in tropical Asia is rainfed and prone to drought. The breeding methods for improving drought tolerance (DT, including genomic selection (GS, are geared to increase the frequency of favorable alleles. Two biparental populations (CIMMYT-Asia Population 1 [CAP1] and CAP2 were generated by crossing elite Asian-adapted yellow inbreds (CML470 and VL1012767 with an African white drought-tolerant line, CML444. Marker effects of polymorphic single-nucleotide polymorphisms (SNPs were determined from testcross (TC performance of F families under drought and optimal conditions. Cycle 1 (C1 was formed by recombining the top 10% of the F families based on TC data. Subsequently, (i C2[PerSe_PS] was derived by recombining those C1 plants that exhibited superior per se phenotypes (phenotype-only selection, and (ii C2[TC-GS] was derived by recombining a second set of C1 plants with high genomic estimated breeding values (GEBVs derived from TC phenotypes of F families (marker-only selection. All the generations and their top crosses to testers were evaluated under drought and optimal conditions. Per se grain yields (GYs of C2[PerSe_PS] and that of C2[TC-GS] were 23 to 39 and 31 to 53% better, respectively, than that of the corresponding F population. The C2[TC-GS] populations showed superiority of 10 to 20% over C2[PerSe-PS] of respective populations. Top crosses of C2[TC-GS] showed 4 to 43% superiority of GY over that of C2[PerSe_PS] of respective populations. Thus, GEBV-enabled selection of superior phenotypes (without the target stress resulted in rapid genetic gains for DT.

  2. Flooding in central Switzerland - Crisis management, experience gained and lessons learned; Hochwasser in der Zentralschweiz

    Energy Technology Data Exchange (ETDEWEB)

    Tresch, F.

    2006-07-01

    This comprehensive article discusses how the Central Switzerland gas, water and power utility ewl, which was stricken in August 2005 by heavy precipitation, flooding and landslides, dealt with the crises thus triggered. Drinking-water pump stations were flooded, a local river tore away a bridge with a natural-gas pipeline and three hydro-power stations had to be powered down. The experience gained in handling this situation was analysed and led to the development of a package of know-how and measures to be taken under similar circumstances. This illustrated article describes the events that happened in detail, with details on the disruption of service and how improvisation helped return supplies of gas, electricity and water to the affected areas as soon as possible. Finally, the article discusses crisis-management aspects and the lessons learned from the disaster.

  3. Slow-light-enhanced gain in active photonic crystal waveguides

    DEFF Research Database (Denmark)

    Ek, Sara; Hansen, Per Lunnemann; Chen, Yaohui

    2014-01-01

    Passive photonic crystals have been shown to exhibit a multitude of interesting phenomena, including slow-light propagation in line-defect waveguides. It was suggested that by incorporating an active material in the waveguide, slow light could be used to enhance the effective gain of the material......, which would have interesting application prospects, for example enabling ultra-compact optical amplifiers for integration in photonic chips. Here we experi- mentally investigate the gain of a photonic crystal membrane structure with embedded quantum wells. We find that by solely changing the photonic...... crystal structural parameters, the maximum value of the gain coefficient can be increased compared with a ridge waveguide structure and at the same time the spectral position of the peak gain be controlled. The experimental results are in qualitative agreement with theory and show that gain values similar...

  4. [Rapid malnutrition in patient with anorexia nervosa: experience of a general pediatric department].

    Science.gov (United States)

    Cros, G; Sznajder, M; Meuric, S; Mignot, C; Chevallier, B; Stheneur, C

    2010-02-01

    Rapid undernutrition in patients with anorexia nervosa can compromise vital functions, notably due to cardiac complications. The aim of this study was to analyze the clinical parameters of anorexic patients, hospitalized for substantial weight loss, in a general pediatric inpatient unit, in order to determine which parameters should be tested by the medical doctor. We performed a retrospective study on 20 consecutive patients (18 girls), median age of 13.75 (+/-2.3) years, admitted for the first time in our pediatric inpatient unit for anorexia nervosa. Symptoms evolved for a median duration of 11.5 (+/-10.2) months before admittance and was shorter for the youngest patients (r = 0.42, p = 0.067). The mean BMI was 13.3 (+/-0.6) kg/m(2) (-3.0+/-1.2 Z-score) and was inversely correlated with serum creatinine levels (74+/-15 micromol/l) (r = 0.44, p case. Mean serum glucose was 3.5+/-1.2 mmol/l. At admittance, an electrocardiogram, performed for 16 patients, showed sinusal bradycardia without conduction impairment. Enteral nutrition was necessary for 14 patients (70%) for a mean duration of 18.1 days (range, 6-56 days). The mean weight gain was 3.1+/-2 kg and was inversely correlated to the BMI at admittance (r = 0.49, p anorexia nervosa is above all clinical, as hematological and biological parameters remain normal for a long time. The cardiac complications found in our study appeared to be more related to the rapid rate of weight loss than to the amount of weight loss itself. Copyright 2009 Elsevier Masson SAS. All rights reserved.

  5. Preliminary Analysis of Rapid Condensation Experiment with MARS-KS Code

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Jae Ho; Jun, Hwang Yong; Jeong, Hae Yong [Sejong University, Seoul (Korea, Republic of)

    2016-05-15

    In the present study, the rapid condensation experiment performed in MANOTEA facility is analyzed with the MARS-KS code. It is known that there exists some limitation with a system code to predict this kind of a very active condensation due to direct mixing of cold injection flow and steam. Through the analysis we investigated the applicability of MARS-KS code for the design of various passive safety systems in the future. The configuration of the experimental facility MANOTEA, which has been constructed at the University of Maryland - United States Naval Academy, is described and the modeling approach using the MARS-KS code is also provided. The preliminary result shows that the MARS-KS predicts the general trend of pressure and temperature in the condensing part correctly. However, it is also found that there exist some limitations in the simulation such as an unexpected pressure peak or a sudden temperature change.

  6. Gain calibration of n-XYTER 1.0 - a prototype readout ASIC for the silicon tracking system of the CBM experiment

    Energy Technology Data Exchange (ETDEWEB)

    Sorokin, Iurii [Goethe Univ. Frankfurt am Main (Germany); Kiev Institute for Nuclear Research (Ukraine); Collaboration: CBM-Collaboration

    2013-07-01

    n-XYTER is a 128-channel readout ASIC which measures both the integral signal charge and the time of occurance. Due to its self-triggering design, high gain, high rate capability and bipolar front-end, the chip has found a use as a prototype readout for the Silicon Tracking System, Muon and Cherenkov detectors of the CBM experiment. It is also going to be applied in other projects in Darmstadt, Heidelberg and Dubna. To perform gain calibration of n-XYTER, reference charge pulses of a very small (down to 3000 e{sup -}), yet precisely known amplitude had to be generated. This was achieved by attenuating a voltage step to a sub-millivolt level and passing it through a tiny (1 pF) capacitor. Special care had to be taken to check for possible systematic errors in the measurements of the attenuation factor and of the coupling capacitance. In addition, the system had to be well shielded against RF pickup, the parasitic capacitances had to be minimized and ensured to stay invariable. Correct estimate of the systematic error was confirmed by performing a measurement with a different signal source - a planar silicon detector, exposed to γ-radiation of {sup 241}Am. Finally, the dominating error came from the channel-to-channel gain variation.

  7. Optical gain in InAs/InGaAs quantum-dot structures: Experiments and theoretical model

    International Nuclear Information System (INIS)

    Eliseev, P G; Li, H; Liu, G T; Stintz, A; Newell, T C; Lester, L E; Malloy, K J

    2000-01-01

    The dependence of the mode optical gain on current in InAs/InGaAs quantum-dot structures grown by the method of molecular-beam epitaxy is obtained from the experimental study of ultra-low-threshold laser diodes. The record lowest inversion threshold at room temperature was about 13 A cm -2 . A theoretical model is proposed that relates the optical gain to the ground-state transitions in quantum dots. The effective gain cross section is estimated to be ∼7 x 10 -15 cm -2 . (lasers)

  8. Implementation of the SSHAC Guidelines for Level 3 and 4 PSHAs - Experience Gained from Actual Applications

    Science.gov (United States)

    Hanks, Thomas C.; Abrahamson, Norm A.; Boore, David M.; Coppersmith, Kevin J.; Knepprath, Nichole E.

    2009-01-01

    In April 1997, after four years of deliberations, the Senior Seismic Hazard Analysis Committee released its report 'Recommendations for Probabilistic Seismic Hazard Analysis: Guidance on Uncertainty and Use of Experts' through the U.S. Nuclear Regulatory Commission as NUREG/CR-6372, hereafter SSHAC (1997). Known informally ever since as the 'SSHAC Guidelines', SSHAC (1997) addresses why and how multiple expert opinions - and the intrinsic uncertainties that attend them - should be used in Probabilistic Seismic Hazard Analyses (PSHA) for critical facilities such as commercial nuclear power plants. Ten years later, in September 2007, the U.S. Geological Survey (USGS) entered into a 13-month agreement with the U.S. Nuclear Regulatory Commission (NRC) titled 'Practical Procedures for Implementation of the SSHAC Guidelines and for Updating PSHAs'. The NRC was interested in understanding and documenting lessons learned from recent PSHAs conducted at the higher SSHAC Levels (3 and 4) and in gaining input from the seismic community for updating PSHAs as new information became available. This study increased in importance in anticipation of new applications for nuclear power facilities at both existing and new sites. The intent of this project was not to replace the SSHAC Guidelines but to supplement them with the experience gained from putting the SSHAC Guidelines to work in practical applications. During the course of this project, we also learned that updating PSHAs for existing nuclear power facilities involves very different issues from the implementation of the SSHAC Guidelines for new facilities. As such, we report our findings and recommendations from this study in two separate documents, this being the first. The SSHAC Guidelines were written without regard to whether the PSHAs to which they would be applied were site-specific or regional in scope. Most of the experience gained to date from high-level SSHAC studies has been for site-specific cases, although three

  9. Mesothelioma as a rapidly developing Giant Abdominal Cyst

    Directory of Open Access Journals (Sweden)

    Vyas Dinesh

    2012-12-01

    Full Text Available Abstract The benign cystic mesothelioma of the peritoneum is a rare lesion and is known for local recurrence. This is first case report of a rapidly developing massive abdominal tumor with histological finding of benign cystic mesothelioma (BCM. We describe a BCM arising in the retroperitoneal tis[sue on the right side, lifting ascending colon and cecum to the left side of abdomen. Patient was an active 58-year-old man who noticed a rapid abdominal swelling within a two month time period with a weight gain of 40 pounds. Patient had no risk factors including occupational (asbestos, cadmium, family history, social (alcohol, smoking or history of trauma. We will discuss the clinical, radiologic, intra-operative, immunohistochemical, pathologic findings, and imaging six months after surgery. Patient has no recurrence and no weight gain on follow up visits and imaging.

  10. The experience of seeking, gaining and maintaining employment after traumatic spinal cord injury and the vocational pathways involved.

    Science.gov (United States)

    Hilton, Gillean; Unsworth, Carolyn A; Stuckey, Ruth; Murphy, Gregory C

    2018-01-01

    Vocational potential in people with spinal cord injury (SCI) are unrealised with rates of employment substantially lower than in the labour force participation of the general population and the pre-injury employment rates. To understand the experience and pathway of people achieving employment outcome after traumatic spinal cord injury by; classifying participants into employment outcome groups of stable, unstable and without employment; identifying pre and post-injury pathways for participants in each group and, exploring the experiences of people of seeking, gaining and maintaining employment. Thirty-one participants were interviewed. Mixed methods approach including interpretive phenomenological analysis and vocational pathway mapping of quantitative data. The most common pathway identified was from study and work pre-injury to stable employment post-injury. Four super-ordinate themes were identified from the interpretive phenomenological analysis; expectations of work, system impacts, worker identity and social supports. Implications for clinical practice include fostering cultural change, strategies for system navigation, promotion of worker identity and optimal use of social supports. The findings increase insight and understanding of the complex experience of employment after spinal cord injury. There is opportunity to guide experimental research, policy development and education concerning the complexity of the return to work experience and factors that influence pathways.

  11. Fetal Programming of Obesity: Maternal Obesity and Excessive Weight Gain

    Directory of Open Access Journals (Sweden)

    Seray Kabaran

    2014-10-01

    Full Text Available The prevalence of obesity is an increasing health problem throughout the world. Maternal pre-pregnancy weight, maternal nutrition and maternal weight gain are among the factors that can cause childhood obesity. Both maternal obesity and excessive weight gain increase the risks of excessive fetal weight gain and high birth weight. Rapid weight gain during fetal period leads to changes in the newborn body composition. Specifically, the increase in body fat ratio in the early periods is associated with an increased risk of obesity in the later periods. It was reported that over-nutrition during fetal period could cause excessive food intake during postpartum period as a result of metabolic programming. By influencing the fetal metabolism and tissue development, maternal obesity and excessive weight gain change the amounts of nutrients and metabolites that pass to the fetus, thus causing excessive fetal weight gain which in turn increases the risk of obesity. Fetal over-nutrition and excessive weight gain cause permanent metabolic and physiologic changes in developing organs. While mechanisms that affect these organs are not fully understood, it is thought that the changes may occur as a result of the changes in fetal energy metabolism, appetite control, neuroendocrine functions, adipose tissue mass, epigenetic mechanisms and gene expression. In this review article, the effects of maternal body weight and weight gain on fetal development, newborn birth weight and risk of obesity were evaluated, and additionally potential mechanisms that can explain the effects of fetal over-nutrition on the risk of obesity were investigated [TAF Prev Med Bull 2014; 13(5.000: 427-434

  12. The experience of dentists who gained enhanced skills in endodontics within a novel pilot training programme.

    Science.gov (United States)

    Eliyas, S; Briggs, P; Gallagher, J E

    2017-02-24

    Objective To explore the experiences of primary care dentists following training to enhance endodontic skills and their views on the implications for the NHS.Design Qualitative study using anonymised free text questionnaires.Setting Primary care general dental services within the National Health Service (NHS) in London, United Kingdom.Subjects and methods Eight primary care dentists who completed this training were asked about factors affecting participant experience of the course, perceived impact on themselves, their organisation, their patients and barriers/facilitators to providing endodontic treatment in NHS primary care. Data were transferred verbatim to a spreadsheet and thematically analysed.Intervention 24-month part-time educational and service initiative to provide endodontics within the NHS, using a combination of training in simulation lab and treatment of patients in primary care.Results Positive impacts were identified at individual (gains in knowledge, skills, confidence, personal development), patient (more teeth saved, quality of care improved) and system levels (access, value for money). Suggested developments for future courses included more case discussions, teaching of practical skills earlier in the course and refinement of the triaging processes. Barriers to using the acquired skills in providing endodontic treatment in primary care within the NHS were perceived to be resources (remuneration, time, skills) and accountability. Facilitators included appropriately remunerated contracts, necessary equipment and time.Conclusion This novel pilot training programme in endodontics combining general practice experience with education/training, hands-on experience and a portfolio was perceived by participants as beneficial for extending skills and service innovation in primary dental care. The findings provide insight into primary dental care practitioners' experience with education/training and have implications for future educational initiatives in

  13. High-resolution stimulated Brillouin gain spectroscopy in glasses and crystals

    International Nuclear Information System (INIS)

    Faris, G.W.; Jusinski, L.E.; Hickman, A.P.

    1993-01-01

    Theory and measurements are presented for stimulated Brillouin gain spectroscopy in anisotropic media. The coupling between arbitrary pump and Stokes waves and the corresponding acoustic wave is formulated in terms of the elastic displacement vector and the photoelastic tensor. A propagation equation that fully includes transient effects is obtained for the Stokes wave. In the limit of small-signal gains this propagation equation can be solved analytically, yielding expressions that relate experimentally accessible quantities to material properties. Absolute Brillouin steady-state gain coefficients, linewidths, and frequency shifts are thereby determined in a number of optical materials at 532 nm. The Brillouin gain coefficient for fused silica is measured by three techniques, providing the reference for absolute gain measurements. Quantitative agreement is found between theory and experiment for transient effects on stimulated Brillouin scattering

  14. Measurement of amplitude fluctuations in a rapid response photomultiplier; Mesure des fluctuations d'amplitude d'un photo multiplicateur a reponse rapide

    Energy Technology Data Exchange (ETDEWEB)

    Raimbault, P [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1961-07-01

    In order to measure amplitude fluctuations in a rapid response photomultiplier, two independent random variables are introduced which determine the shape of the anode pulse. The energy of each pulse, which depends directly on the gain and the variance, is the first variable; amplitude fluctuations, functions of the first variable, depend as well on the pulse width which in turn constitutes the second variable. The results obtained on the variations of the maximum impulse, using a steep-edged pulse broadening circuit, and those obtained on the statistical variations of the gain, are compared to show that the variance relative to the maximum amplitude of the signal is greater than that of the gain. Within the limits of these fluctuations are shown the contribution of the secondary emission coefficient of the first dynode, and that of the mean secondary emission coefficient of the multiplier. (author) [French] Pour etudier les fluctuations d'amplitude d'un photomultiplicateur a reponse rapide, on introduit deux variables aleatoires independantes qui determinent la forme de l'impulsion anodique. L'energie de chaque impulsion, directement fonction du gain et de sa variance, est la premiere variable; les fluctuations d'amplitude, fonctions de la premiere variable, dependent egalement de la largeur de l'impulsion qui, elle, constitue la deuxieme variable. Les resultats obtenus sur les variations de l'amplitude maximale, a l'aide d'un circuit elargisseur d'impulsions a front raide, et les resultats des variations statistiques du gain sont compares pour mettre en evidence le fait que la variance relative a l'amplitude maximale du signal est plus grande que celle du gain. Dans la mesure de ces fluctuations, sont mises en evidence la contribution du coefficient d'emission secondaire de la premiere dynode et celle du coefficient d'emission secondaire moyen du multiplicateur. (auteur)

  15. Sound pressure gain produced by the human middle ear.

    Science.gov (United States)

    Kurokawa, H; Goode, R L

    1995-10-01

    The acoustic function of the middle ear is to match sound passing from the low impedance of air to the high impedance of cochlear fluid. Little information is available on the actual middle ear pressure gain in human beings. This article describes experiments on middle ear pressure gain in six fresh human temporal bones. Stapes footplate displacement and phase were measured with a laser Doppler vibrometer before and after removal of the tympanic membrane, malleus, and incus. Acoustic insulation of the round window with clay was performed. Umbo displacement was also measured before tympanic membrane removal to assess baseline tympanic membrane function. The middle ear has its major gain in the lower frequencies, with a peak near 0.9 kHz. The mean gain was 23.0 dB below 1.0 kHz, the resonant frequency of the middle ear; the mean peak gain was 26.6 dB. Above 1.0 kHz, the second pressure gain decreased at a rate of -8.6 dB/octave, with a mean gain of 6.5 dB at 4.0 kHz. Only a small amount of gain was present above 7.0 kHz. Significant individual differences in pressure gain were found between ears that appeared related to variations in tympanic membrane function and not to variations in cochlear impedance.

  16. Potential gains from hospital mergers in Denmark.

    Science.gov (United States)

    Kristensen, Troels; Bogetoft, Peter; Pedersen, Kjeld Moeller

    2010-12-01

    The Danish hospital sector faces a major rebuilding program to centralize activity in fewer and larger hospitals. We aim to conduct an efficiency analysis of hospitals and to estimate the potential cost savings from the planned hospital mergers. We use Data Envelopment Analysis (DEA) to estimate a cost frontier. Based on this analysis, we calculate an efficiency score for each hospital and estimate the potential gains from the proposed mergers by comparing individual efficiencies with the efficiency of the combined hospitals. Furthermore, we apply a decomposition algorithm to split merger gains into technical efficiency, size (scale) and harmony (mix) gains. The motivation for this decomposition is that some of the apparent merger gains may actually be available with less than a full-scale merger, e.g., by sharing best practices and reallocating certain resources and tasks. Our results suggest that many hospitals are technically inefficient, and the expected "best practice" hospitals are quite efficient. Also, some mergers do not seem to lower costs. This finding indicates that some merged hospitals become too large and therefore experience diseconomies of scale. Other mergers lead to considerable cost reductions; we find potential gains resulting from learning better practices and the exploitation of economies of scope. To ensure robustness, we conduct a sensitivity analysis using two alternative returns-to-scale assumptions and two alternative estimation approaches. We consistently find potential gains from improving the technical efficiency and the exploitation of economies of scope from mergers.

  17. Response time distributions in rapid chess: a large-scale decision making experiment.

    Science.gov (United States)

    Sigman, Mariano; Etchemendy, Pablo; Slezak, Diego Fernández; Cecchi, Guillermo A

    2010-01-01

    Rapid chess provides an unparalleled laboratory to understand decision making in a natural environment. In a chess game, players choose consecutively around 40 moves in a finite time budget. The goodness of each choice can be determined quantitatively since current chess algorithms estimate precisely the value of a position. Web-based chess produces vast amounts of data, millions of decisions per day, incommensurable with traditional psychological experiments. We generated a database of response times (RTs) and position value in rapid chess games. We measured robust emergent statistical observables: (1) RT distributions are long-tailed and show qualitatively distinct forms at different stages of the game, (2) RT of successive moves are highly correlated both for intra- and inter-player moves. These findings have theoretical implications since they deny two basic assumptions of sequential decision making algorithms: RTs are not stationary and can not be generated by a state-function. Our results also have practical implications. First, we characterized the capacity of blunders and score fluctuations to predict a player strength, which is yet an open problem in chess softwares. Second, we show that the winning likelihood can be reliably estimated from a weighted combination of remaining times and position evaluation.

  18. Response time distributions in rapid chess: A large-scale decision making experiment

    Directory of Open Access Journals (Sweden)

    Mariano Sigman

    2010-10-01

    Full Text Available Rapid chess provides an unparalleled laboratory to understand decision making in a natural environment. In a chess game, players choose consecutively around 40 moves in a finite time budget. The goodness of each choice can be determined quantitatively since current chess algorithms estimate precisely the value of a position. Web-based chess produces vast amounts of data, millions of decisions per day, incommensurable with traditional psychological experiments. We generated a database of response times and position value in rapid chess games. We measured robust emergent statistical observables: 1 Response time (RT distributions are long-tailed and show qualitatively distinct forms at different stages of the game, 2 RT of successive moves are highly correlated both for intra- and inter-player moves. These findings have theoretical implications since they deny two basic assumptions of sequential decision making algorithms: RTs are not stationary and can not be generated by a state function. Our results also have practical implications. First, we characterized the capacity of blunders and score fluctuations to predict a player strength, which is yet an open problem in chess softwares. Second, we show that the winning likelihood can be reliably estimated from a weighted combination of remaining times and position evaluation.

  19. Temporal dynamics of contrast gain in single cells of the cat striate cortex.

    Science.gov (United States)

    Bonds, A B

    1991-03-01

    The response amplitude of cat striate cortical cells is usually reduced after exposure to high-contrast stimuli. The temporal characteristics and contrast sensitivity of this phenomenon were explored by stimulating cortical cells with drifting gratings in which contrast sequentially incremented and decremented in stepwise fashion over time. All responses showed a clear hysteresis, in which contrast gain dropped on average 0.36 log unit and then returned to baseline values within 60 s. Noticeable gain adjustments were seen in as little as 3 s and with peak contrasts as low as 3%. Contrast adaptation was absent in responses from LGN cells. Adaptation was found to depend on temporal frequency of stimulation, with greater and more rapid adaptation at higher temporal frequencies. Two different tests showed that the mechanism controlling response reduction was influenced primarily by stimulus contrast rather than response amplitude. These results support the existence of a rapid and sensitive cortically based system that normalizes the output of cortical cells as a function of local mean contrast. Control of the adaptation appears to arise at least in part across a population of cells, which is consistent with the idea that the gain control serves to limit the information converging from many cells onto subsequent processing areas.

  20. Kaizen Costing: Experience and Prospects of Implementation at Industrial Enterprises of Ukraine

    OpenAIRE

    Kachalay Valeriy V.

    2013-01-01

    The article focuses on a necessity to apply effective methods of cost accounting of products for gaining competitive advantages by the Ukrainian industrial enterprises in the world market of goods and services. It describes the essence of the kaizen costing as a process of continuous and gradual improvement and also identifies factors, which de-stimulate rapid propagation of these methods of cost accounting at domestic enterprises. It provides experience of its implementation at the Ukrainian...

  1. Gestational weight gain.

    Science.gov (United States)

    Kominiarek, Michelle A; Peaceman, Alan M

    2017-12-01

    Prenatal care providers are advised to evaluate maternal weight at each regularly scheduled prenatal visit, monitor progress toward meeting weight gain goals, and provide individualized counseling if significant deviations from a woman's goals occur. Today, nearly 50% of women exceed their weight gain goals with overweight and obese women having the highest prevalence of excessive weight gain. Risks of inadequate weight gain include low birthweight and failure to initiate breast-feeding whereas the risks of excessive weight gain include cesarean deliveries and postpartum weight retention for the mother and large-for-gestational-age infants, macrosomia, and childhood overweight or obesity for the offspring. Prenatal care providers have many resources and tools to incorporate weight and other health behavior counseling into routine prenatal practices. Because many women are motivated to improve health behaviors, pregnancy is often considered the optimal time to intervene for issues related to eating habits and physical activity to prevent excessive weight gain. Gestational weight gain is a potentially modifiable risk factor for a number of adverse maternal and neonatal outcomes and meta-analyses of randomized controlled trials report that diet or exercise interventions during pregnancy can help reduce excessive weight gain. However, health behavior interventions for gestational weight gain have not significantly improved other maternal and neonatal outcomes and have limited effectiveness in overweight and obese women. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC - the Hot Start experience

    Directory of Open Access Journals (Sweden)

    Paul A. De Sousa

    2017-04-01

    eTOC: The report focuses on the EBiSC experience of rapidly establishing an operational capacity to procure, bank and distribute a foundational collection of established hiPSC lines. It validates the feasibility and defines the challenges of harnessing and integrating the capability and productivity of centres across Europe using commonly available resources currently in the field.

  3. Operational gain : measuring the capture of genetic gain ...

    African Journals Online (AJOL)

    The concept of operational gain is more than the weighted average of the genetic quality of planted hectares, and encompasses tree breeding efficiencies, propagation efficiencies, matching of species and genotype to site, plant use efficiency and early measures of stand density and growth. To test the operational gain ...

  4. Individual language experience modulates rapid formation of cortical memory circuits for novel words

    Science.gov (United States)

    Kimppa, Lilli; Kujala, Teija; Shtyrov, Yury

    2016-01-01

    Mastering multiple languages is an increasingly important ability in the modern world; furthermore, multilingualism may affect human learning abilities. Here, we test how the brain’s capacity to rapidly form new representations for spoken words is affected by prior individual experience in non-native language acquisition. Formation of new word memory traces is reflected in a neurophysiological response increase during a short exposure to novel lexicon. Therefore, we recorded changes in electrophysiological responses to phonologically native and non-native novel word-forms during a perceptual learning session, in which novel stimuli were repetitively presented to healthy adults in either ignore or attend conditions. We found that larger number of previously acquired languages and earlier average age of acquisition (AoA) predicted greater response increase to novel non-native word-forms. This suggests that early and extensive language experience is associated with greater neural flexibility for acquiring novel words with unfamiliar phonology. Conversely, later AoA was associated with a stronger response increase for phonologically native novel word-forms, indicating better tuning of neural linguistic circuits to native phonology. The results suggest that individual language experience has a strong effect on the neural mechanisms of word learning, and that it interacts with the phonological familiarity of the novel lexicon. PMID:27444206

  5. Baby Jupiters Must Gain Weight Fast

    Science.gov (United States)

    2009-01-01

    This photograph from NASA's Spitzer Space Telescope shows the young star cluster NGC 2362. By studying it, astronomers found that gas giant planet formation happens very rapidly and efficiently, within less than 5 million years, meaning that Jupiter-like worlds experience a growth spurt in their infancy.

  6. The effects of control-display gain on performance of race car drivers in an isometric braking task.

    Science.gov (United States)

    de Winter, J C F; de Groot, S

    2012-12-01

    To minimise lap times during car racing, it is important to build up brake forces rapidly and maintain precise control. We examined the effect of the amplification factor (gain) between brake pedal force and a visually represented output value on a driver's ability to track a target value. The test setup was a formula racing car cockpit fitted with an isometric brake pedal. Thirteen racing drivers performed tracking tasks with four control-display gains and two target functions: a step function (35 trials per gain) and a multisine function (15 trials per gain). The control-display gain had only minor effects on root mean-squared error between output value and target value, but it had large effects on build-up speed, overshoot, within-participants variability, and self-reported physical load. The results confirm the hypothesis that choosing an optimum gain involves balancing stability against physical effort.

  7. Antipsychotic-associated weight gain: management strategies and impact on treatment adherence

    Directory of Open Access Journals (Sweden)

    Dayabandara M

    2017-08-01

    Full Text Available Madhubhashinee Dayabandara, Raveen Hanwella, Suhashini Ratnatunga, Sudarshi Seneviratne, Chathurie Suraweera, Varuni A de Silva Department of Psychiatry, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka Abstract: Antipsychotic-induced weight gain is a major management problem for clinicians. It has been shown that weight gain and obesity lead to increased cardiovascular and cerebrovascular morbidity and mortality, reduced quality of life and poor drug compliance. This narrative review discusses the propensity of various antipsychotics to cause weight gain, the pharmacologic and nonpharmacologic interventions available to counteract this effect and its impact on adherence. Most antipsychotics cause weight gain. The risk appears to be highest with olanzapine and clozapine. Weight increases rapidly in the initial period after starting antipsychotics. Patients continue to gain weight in the long term. Children appear to be particularly vulnerable to antipsychotic-induced weight gain. Tailoring antipsychotics according to the needs of the individual and close monitoring of weight and other metabolic parameters are the best preventive strategies at the outset. Switching to an agent with lesser tendency to cause weight gain is an option, but carries the risk of relapse of the illness. Nonpharmacologic interventions of dietary counseling, exercise programs and cognitive and behavioral strategies appear to be equally effective in individual and group therapy formats. Both nonpharmacologic prevention and intervention strategies have shown modest effects on weight. Multiple compounds have been investigated as add-on medications to cause weight loss. Metformin has the best evidence in this respect. Burden of side effects needs to be considered when prescribing weight loss medications. There is no strong evidence to recommend routine prescription of add-on medication for weight reduction. Heterogeneity of study methodologies and other

  8. Experience gained in gamma spectroscopy; Experience acquise dans la spectrometrie gamma

    Energy Technology Data Exchange (ETDEWEB)

    Jeanmaire, L [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    There are two types of method which make it possible to estimate the internal contamination of individuals. On the one hand these are the indirect techniques based on measurements of the excreted products, on the other there are the direct techniques in which attempts are made to measure directly the radio-activity existing in the organism. We propose to give a few of the results obtained by the direct method using equipment built by the Commissariat a l'Energie Atomique. The apparatus consists of a {gamma} spectrometer. It includes: 1) A crystal of sodium iodide 20 cm in diameter and 10 cm high. The large size of this crystal ensures a good sensitivity and makes it possible to carry out rapid measurements. 2) A 25 channel type SAE 25 selector which classifies the pulses according to their amplitude. It is therefore possible to distinguish between {gamma} rays of varying energy. 3) A comparatively very light radiation protection, consisting of only 5 cm thickness of lead which diminishes the ambient {gamma} ray intensity to a sufficient level for the majority of the measurements. A certain collimation is thus obtained which makes it possible to localise the source approximately and to reduce the undesirable effects of external contamination. (author) [French] Deux types de methodes permettent d'apprecier la contamination interne d'un individu. D'une part, les techniques indirectes basees sur la mesure des produits excretes, d'autre part, les techniques directes au moyen desquelles on essaie de mesurer directement la radioactivite existant dans l'organisme. Nous nous proposons d'indiquer quelques resultats obtenus par la methode directe, au moyen d'ensembles realises par le Commissariat a l'Energie Atomique. L'appareillage est un spectrometre {gamma}. II comprend: 1) Un cristal d'iodure de sodium de 20 cm de diametre et 10 cm de hauteur. La grande taille de ce cristal assure une bonne sensibilite et permet d'effectuer des mesures rapides. 2) Un selecteur a 25 canaux

  9. Rapid and sustained cost management

    International Nuclear Information System (INIS)

    Hanson, D.

    2009-01-01

    Accenture helps clients develop comprehensive, process-driven strategies for rapid and sustained cost management that leverage deep insights and analytics. This approach enables companies to gain operating cost advantages by rationalizing, simplifying and automating current operating capabilities. It drives structural cost advantages by optimizing business mix, capital structure, organizational structure and geographic presence. This paper discussed how successful companies achieve high performance during times of economic turmoil. It also discussed the value of the winner's strategy in terms of rapid and sustained cost management (RSCM). It discussed how Accenture operates and its leveraged capabilities, improved efficiency, margins and cash flow while maintaining customer service levels. Building structural advantage and the Accenture difference were also discussed. It was concluded that RSCM is one vital way that Accenture can help companies achieve success. 4 figs

  10. Risk Insights Gained from Fire Incidents

    International Nuclear Information System (INIS)

    Kazarians, Mardy; Nowlen, Steven P.

    1999-01-01

    There now exist close to 20 years of history in the application of Probabilistic Risk Assessment (PRA) for the analysis of fire risk at nuclear power plants. The current methods are based on various assumptions regarding fire phenomena, the impact of fire on equipment and operator response, and the overall progression of a fire event from initiation through final resolution. Over this same time period, a number of significant fire incidents have occurred at nuclear power plants around the world. Insights gained from US experience have been used in US studies as the statistical basis for establishing fire initiation frequencies both as a function of the plant area and the initiating fire source.To a lesser extent, the fire experience has also been used to assess the general severity and duration of fires. However, aside from these statistical analyses, the incidents have rarely been scrutinized in detail to verify the underlying assumptions of fire PRAs. This paper discusses an effort, under which a set of fire incidents are being reviewed in order to gain insights directly relevant to the methods, data, and assumptions that form the basis for current fire PRAs. The paper focuses on the objectives of the effort, the specific fire events being reviews methodology, and anticipated follow-on activities

  11. MOS current gain cells with electronically variable gain and constant bandwidth

    NARCIS (Netherlands)

    Klumperink, Eric A.M.; Seevinck, Evert

    1989-01-01

    Two MOS current gain cells are proposed that provide linear amplification of currents supplied by several linear MOS V-I converters. The gain is electronically variable by a voltage or a current and can be made insensitive to temperature and IC processing. The gain cells have a constant

  12. Gain dynamics of quantum dot devices for dual-state operation

    Energy Technology Data Exchange (ETDEWEB)

    Kaptan, Y., E-mail: yuecel.kaptan@physik.tu-berlin.de; Herzog, B.; Kolarczik, M.; Owschimikow, N.; Woggon, U. [Institut für Optik und Atomare Physik, Technische Universität Berlin, Berlin (Germany); Schmeckebier, H.; Arsenijević, D.; Bimberg, D. [Institut für Festkörperphysik, Technische Universität Berlin, Berlin (Germany); Mikhelashvili, V.; Eisenstein, G. [Technion Institute of Technology, Faculty of Electrical Engineering, Haifa (Israel)

    2014-06-30

    Ground state gain dynamics of In(Ga)As-quantum dot excited state lasers are investigated via single-color ultrafast pump-probe spectroscopy below and above lasing threshold. Two-color pump-probe experiments are used to localize lasing and non-lasing quantum dots within the inhomogeneously broadened ground state. Single-color results yield similar gain recovery rates of the ground state for lasing and non-lasing quantum dots decreasing from 6 ps to 2 ps with increasing injection current. We find that ground state gain dynamics are influenced solely by the injection current and unaffected by laser operation of the excited state. This independence is promising for dual-state operation schemes in quantum dot based optoelectronic devices.

  13. Rapid prototyping using CBCT: an initial experience

    International Nuclear Information System (INIS)

    Yovchev, D.; Deliverska, E.; Indjova, J.; Ugrinov, R.

    2011-01-01

    This report presents a case of fibrous dysplasia in the left lower jaw of a 12-year-old girl, scanned with CBCT. On the basis of CBCT scan a model of affected jaw was produced using a rapid-prototyping three-dimensional printer. The case demonstrates the possibility to get a prototype by CBCT data. Prototypes can be used to support the diagnosis, planning, training (students and postgraduates) and to obtain informed consent from the patient.

  14. Syndromes of rapidly progressive cognitive decline-our experience

    Directory of Open Access Journals (Sweden)

    Sadanandavalli Retnaswami Chandra

    2017-01-01

    Full Text Available Background: Dementias are fairly slowly progressive degenerative diseases of brain for which treatment options are very less and carry a lot of burden on family and society. A small percentage of them are rapidly progressive and mostly carry a different course outcome. However, there are no definite criteria other than the time line for these patients. Aims: The aim of this was to identify and categorize the causes and course of rapidly progressive dementias seen in our center. Settings and Design: Patients who presented with rapid deterioration of cognitive functions within weeks to 1 year between 2011 and December 2016 were evaluated. Patients and Methods: All patients underwent all mandatory tests for dementia including brain imaging. Complete vasculitis workup, autoimmune encephalitis profile including Voltage Gated Potassium Channel, N-methyl-D-aspartic acid receptor, glutamic acid-decarboxylase, thyroid-peroxidase antibody, cerebrospinal fluid, and other special tests such as duodenal biopsy and paraneoplastic workup were done based on clinical indications. Results and Conclusions: Out of 144 patients 42 had immune-mediated encephalopathy, 18 had Creutzfeldt-Jakob disease, 3 had Vitamin B12 deficiency, 63 had infection with neurocysticercosis, 7 had tuberculosis, 2 had HIV, 1 had herpes simplex encephalitis, 1 had neurosyphilis, 1 Whipples disease, 1 had Subacute Sclerosing Panencephalitis, 1 had Mass lesion, 3 had Frontotemporal dementia, and 3 had small vessel disease. Good majority of these patients have infective and immune-mediated causes and less number belong to degenerative group. Therefore, caution is needed to look for treatable cause as it carries a different treatment options and outcome.

  15. Using Rapid Improvement Events for Disaster After-Action Reviews: Experience in a Hospital Information Technology Outage and Response.

    Science.gov (United States)

    Little, Charles M; McStay, Christopher; Oeth, Justin; Koehler, April; Bookman, Kelly

    2018-02-01

    The use of after-action reviews (AARs) following major emergency events, such as a disaster, is common and mandated for hospitals and similar organizations. There is a recurrent challenge of identified problems not being resolved and repeated in subsequent events. A process improvement technique called a rapid improvement event (RIE) was used to conduct an AAR following a complete information technology (IT) outage at a large urban hospital. Using RIE methodology to conduct the AAR allowed for the rapid development and implementation of major process improvements to prepare for future IT downtime events. Thus, process improvement methodology, particularly the RIE, is suited for conducting AARs following disasters and holds promise for improving outcomes in emergency management. Little CM , McStay C , Oeth J , Koehler A , Bookman K . Using rapid improvement events for disaster after-action reviews: experience in a hospital information technology outage and response. Prehosp Disaster Med. 2018;33(1):98-100.

  16. Coating process optimization through in-line monitoring for coating weight gain using Raman spectroscopy and design of experiments.

    Science.gov (United States)

    Kim, Byungsuk; Woo, Young-Ah

    2018-05-30

    In this study the authors developed a real-time Process Analytical Technology (PAT) of a coating process by applying in-line Raman spectroscopy to evaluate the coating weight gain, which is a quantitative analysis of the film coating layer. The wide area illumination (WAI) Raman probe was connected to the pan coater for real-time monitoring of changes in the weight gain of coating layers. Under the proposed in-line Raman scheme, a non-contact, non-destructive analysis was performed using WAI Raman probes with a spot size of 6 mm. The in-line Raman probe maintained a focal length of 250 mm, and a compressed air line was designed to protect the lens surface from spray droplets. The Design of Experiment (DOE) was applied to identify factors affecting the Raman spectra background of laser irradiation. The factors selected for DOE were the strength of compressed air connected to the probe, and the shielding of light by the transparent door connecting the probe to the pan coater. To develop a quantitative model, partial least squares (PLS) models as multivariate calibration were developed based on the three regions showing the specificity of TiO 2 individually or in combination. For the three single peaks (636 cm -1 , 512 cm -1 , 398 cm -1 ), least squares method (LSM) was applied to develop three univariate quantitative analysis models. One of best multivariate quantitative model having a factor of 1 gave the lowest RMSEP of 0.128, 0.129, and 0.125, respectively for prediction batches. When LSM was applied to the single peak at 636 cm -1 , the univariate quantitative model with an R 2 of 0.9863, slope of 0.5851, and y-intercept of 0.8066 had the lowest RMSEP of 0.138, 0.144, and 0.153, respectively for prediction batches. The in-line Raman spectroscopic method for the analysis of coating weight gain was verified by considering system suitability and parameters such as specificity, range, linearity, accuracy, and precision in accordance with ICH Q2 regarding

  17. Polygenic Risk, Appetite Traits, and Weight Gain in Middle Childhood

    Science.gov (United States)

    Steinsbekk, Silje; Belsky, Daniel; Guzey, Ismail Cuneyt; Wardle, Jane; Wichstrøm, Lars

    2018-01-01

    weight and fat mass more rapidly during follow-up. Each SD increase in genetic risk score was associated with a 0.22-point increase in BMI at age-4 baseline (for the intercept, unstandardized path coefficient B = 0.22 [95%CI, 0.06–0.38]; P = .008. Children with higher genetic risk scores also gained BMI points more rapidly from ages 4 to 6 years (B = 0.11 [95% CI, 0.03–0.20]; P = .01 ; β = 0.12) and from 6 to 8 years (B = 0.09 [95%CI, 0.00–0.19]; P = .05; β = 0.10), compared with their lower genetic risk peers. Children at higher genetic risk had higher levels of alleged obesogenic appetite traits than peers with lower genetic risk at age 6 years, but appetite traits did not mediate genetic associations with weight gain. The sum of the 5 indirect effects was B = −0.001 (95%CI, −0.02 –0.01); P = .86; β = 0.00. CONCLUSIONS AND RELEVANCE Genetic risk for obesity is associated with accelerated childhood weight gain. Interventions targeting childhood weight gain may provide one path to mitigating genetic risk. However, middle childhood appetite traits may not be a promising target for such interventions. Studies of early-childhood samples are needed to test whether appetite traits explain how genetic risks accelerate growth earlier in development. PMID:26830872

  18. The effect of above average weight gains on the incidence of radiographic bone aberrations and epiphysitis in growing horses

    International Nuclear Information System (INIS)

    Thompson, K.N.; Jackson, S.G.; Rooney, J.R.

    1988-01-01

    The relationship between body weight gain and the onset of bone aberrations (e.g. epiphysitis) is described. A model was derived which described the increase in transverse epiphyseal width, and the major factor found to affect epiphyseal width was average daily gain in body weight. In addition, a radiographic examination of the epiphyseal areas showed a larger number of bone aberrations in groups gaining weight at an above-average rate. Thus, a rapid increase in body weight can be suggested as a significant factor in the onset of epiphysitis

  19. The Rapid Perceptual Impact of Emotional Distractors.

    Directory of Open Access Journals (Sweden)

    Briana L Kennedy

    Full Text Available The brief presentation of an emotional distractor can temporarily impair perception of a subsequent, rapidly presented target, an effect known as emotion-induced blindness (EIB. How rapidly does this impairment unfold? To probe this question, we examined EIB for targets that immediately succeeded ("lag-1" emotional distractors in a rapid stream of items relative to EIB for targets at later serial positions. Experiments 1 and 2 suggested that emotional distractors interfere with items presented very soon after them, with impaired target perception emerging as early as lag-1. Experiment 3 included an exploratory examination of individual differences, which suggested that EIB onsets more rapidly among participants scoring high in measures linked to negative affect.

  20. Optical gain and gain suppression of quantum-well lasers with valence band mixing

    International Nuclear Information System (INIS)

    Ahn, D.; Chuang, S.L.

    1990-01-01

    The effects of valence band mixing on the nonlinear gains of quantum-well lasers are studied theoretically. The authors' analysis is based on the multiband effective-mass theory and the density matrix formalism with intraband relaxation taken into account. The gain and the gain-suppression coefficient of a quantum-well laser are calculated from the complex optical susceptibility obtained by the density matrix formulation with the theoretical dipole moments obtained from the multiband effective-mass theory. The calculated gain spectrum shows that there are remarkable differences (both in peak amplitude and spectral shape) between our model with valence band mixing and the conventional parabolic band model. The shape of the gain spectrum calculated by the authors' model becomes more symmetric due to intraband relaxation together with nonparabolic energy dispersions and is closer to the experimental observations when compared with the conventional method using the parabolic band model and the multiband effective-mass calculation without intraband relaxation. Both give quite asymmetric gain spectra. Optical intensity in the GaAs active region is estimated by solving rate equations for the stationary states with nonlinear gain suppression. The authors calculate the mode gain for the resonant mode including the gain suppression, which results in spectral hole burning of the gain spectrum

  1. Experience Learning and Community Development

    Directory of Open Access Journals (Sweden)

    Nena Mijoč

    1996-12-01

    Full Text Available Research in the field of education, carried out in living and working environment, which has undergone so profound changes recently, is of extreme importance. In schools, courses and seminars, one cannot prepare him/herself for the changes as these are often so rapid that it is impossible to foresee them. Therefore, one can only learn by experience. In defining the term 'experience learning', the teoreticians vary greatly. In this paper, experience learning is understood as a process of learning taking part mainly outside the planned educational process and including an active and participative attitude towards environment and people. Original and direct experience can thus serve as a basis for gaining new comprehensions, for planning future activities as well as for a reinterpretation of the past experiences. Let us first mention the basic factors of successful experience learning, such as an individual's character features, possibilities for learning, learning atmosphere and positive stimulations. It has been estimated that local community can increase or decrease the possibilities for experience learning. However, the relation is active in other direction too: the more experience learning bas been asserted in a community, the greater its influence on social and cultural development of the community. On has to bear in mind that well-planned education for local community and stimulating sociocultural animation can facilitate the development of local community.

  2. Rapid improvement teams.

    Science.gov (United States)

    Alemi, F; Moore, S; Headrick, L; Neuhauser, D; Hekelman, F; Kizys, N

    1998-03-01

    Suggestions, most of which are supported by empirical studies, are provided on how total quality management (TQM) teams can be used to bring about faster organizationwide improvements. Ideas are offered on how to identify the right problem, have rapid meetings, plan rapidly, collect data rapidly, and make rapid whole-system changes. Suggestions for identifying the right problem include (1) postpone benchmarking when problems are obvious, (2) define the problem in terms of customer experience so as not to blame employees nor embed a solution in the problem statement, (3) communicate with the rest of the organization from the start, (4) state the problem from different perspectives, and (5) break large problems into smaller units. Suggestions for having rapid meetings include (1) choose a nonparticipating facilitator to expedite meetings, (2) meet with each team member before the team meeting, (3) postpone evaluation of ideas, and (4) rethink conclusions of a meeting before acting on them. Suggestions for rapid planning include reducing time spent on flowcharting by focusing on the future, not the present. Suggestions for rapid data collection include (1) sample patients for surveys, (2) rely on numerical estimates by process owners, and (3) plan for rapid data collection. Suggestions for rapid organizationwide implementation include (1) change membership on cross-functional teams, (2) get outside perspectives, (3) use unfolding storyboards, and (4) go beyond self-interest to motivate lasting change in the organization. Additional empirical investigations of time saved as a consequence of the strategies provided are needed. If organizations solve their problems rapidly, fewer unresolved problems may remain.

  3. Predicting the gain from deliquification measures for European wells

    NARCIS (Netherlands)

    Nennie, E.D.; Boer, J.P. de; Schiferli, W.

    2014-01-01

    Various Dutch operators have identified a need for increased application of deliquification measures in their North Sea wells. To help meet this need a Joint Industry Project (JIP) was set up to identify knowledge and experience gained in the United States on gas well deliquification and transfer

  4. New experiment to gain unparalleled insight into antimatter

    CERN Multimedia

    Katarina Anthony

    2013-01-01

    At last week’s Research Board meeting, the Baryon Antibaryon Symmetry Experiment (BASE) was approved for installation at CERN. The experiment will be diving into the search for matter-antimatter asymmetry, as it aims to take ultra-high precision measurements of the antiproton magnetic moment.   CERN's AD Hall: the new home of the BASE double Penning trap set-up. The BASE collaboration will be setting up shop in the AD Hall this September with its first CERN-based experimental set-up. Using the novel double-Penning trap set-up developed at the University of Mainz, GSI Darmstadt and the Max Plank Institute for Nuclear Physics (Germany), the BASE team will be able to measure the antiproton magnetic moment with hitherto unreachable part-per-billion precision. “We constructed the first double-Penning trap at our companion facility in Germany, and made the first ever direct observations of single spin flips of a single proton,” explains Stefan Ulmer from RIKE...

  5. A new approach to assess student perceptions of gains from an REU program

    Science.gov (United States)

    Houser, C.; Cahill, A. T.; Lemmons, K.

    2013-12-01

    Research Experience for Undergraduate (REU) programs are designed to recruit students to science and engineering research careers by allowing the students to conduct research with faculty mentors. The success of REU programs is commonly assessed based on student perceptions of gains using a simple Likert scale. Because students tend to be positive about all aspects of their research experience, the results of the Likert scale tend to be meaningless. An alternative assessment technique, similar to Q-analysis, is used to assess the perceived outcomes of an international REU program hosted by Texas A&M University. Students were required to sort commonly identified REU outcomes into a normal distribution, from most agree to least agree, based on what they perceive as their personal gains from the program. Factor analysis reveals 3 groups of students who believe that they gained field and analytical skills (Group 1), greater competence in research and self-confidence (Group 2), and an improved understanding of the scientific method (Group 3). Student perceptions appear to depend on whether the student had previous research experience through classes and/or as a research assistant at their home institution. A comparison to a similar sort of REU outcomes by the faculty mentors suggests that there is a slight disconnect in the perceived gains by the students between the student participants and the faculty mentors.

  6. Rapid Adaptation in Digital Transformation

    DEFF Research Database (Denmark)

    Hansen, Anne Mette; Kræmmergaard, Pernille; Mathiassen, Lars

    2011-01-01

    landscape. In this article, we share insights gained from two public sector organizations in which IS and business leaders used the Participatory Process Model (PPM) designed by the authors to share their assumptions about IS leadership, challenge existing IT strategies and collaboration patterns and adapt...... the organization’s digitization approach. We demonstrate in detail how the leaders within these two organizations were engaged and offer recommendations for how other organizations can use the PPM to rapidly adapt their approaches to digital transformation through more effective IS leadership roles....

  7. The Neural Responses to Social Cooperation in Gain and Loss Context.

    Directory of Open Access Journals (Sweden)

    Peng Sun

    Full Text Available Cooperation is pervasive and constitutes the core behavioral principle of human social life. Previous studies have revealed that mutual cooperation was reliably correlated with two reward-related brain regions, the ventral striatum and the orbitofrontal cortex. Using functional magnetic resonance imaging (fMRI, this study sought to investigate how the loss and gain contexts modulated the neural responses to mutual cooperation. Twenty-five female participants were scanned when they played a series of one-shot prisoner's dilemma games in the loss and gain contexts. Specifically, participants and partners independently chose to either cooperate with each other or not, and each was awarded or deprived of (in the gain context or the loss context, respectively a sum of money which depended upon the interaction of their choices. Behavioral results indicated that participants cooperated in nearly half of the experiment trials and reported higher level of positive emotions for mutual cooperation in both contexts, but they cooperated more in the gain than in the loss context. At the neural level, stronger activities in the orbitofrontal cortex were observed for mutual cooperation compared with the other three outcomes in both contexts, while stronger activation in ventral striatum associated with mutual cooperation was observed in the gain context only. Together, our data indicated that, even in the one-shot interaction under loss context, participants still exhibited preference for cooperation and the rewarding experience from a mutually cooperative social interaction activated the ventral striatum and the orbitofrontal cortex, but the loss context weakened the association between the ventral striatum activation and mutual cooperation.

  8. Rapid growth and childhood obesity are strongly associated with lysoPC(14:0).

    Science.gov (United States)

    Rzehak, Peter; Hellmuth, Christian; Uhl, Olaf; Kirchberg, Franca F; Peissner, Wolfgang; Harder, Ulrike; Grote, Veit; Weber, Martina; Xhonneux, Annick; Langhendries, Jean-Paul; Ferre, Natalia; Closa-Monasterolo, Ricardo; Verduci, Elvira; Riva, Enrica; Socha, Piotr; Gruszfeld, Dariusz; Koletzko, Berthold

    2014-01-01

    Despite the growing interest in the early-origins-of-later-disease hypothesis, little is known about the metabolic underpinnings linking infant weight gain and childhood obesity. To discover biomarkers reflective of weight change in the first 6 months and overweight/obesity at age 6 years via a targeted metabolomics approach. This analysis comprised 726 infants from a European multicenter randomized trial (Childhood Obesity Programme, CHOP) for whom plasma blood samples at age 6 months and anthropometric data up to the age of 6 years were available. 'Rapid growth' was defined as a positive difference in weight within the first 6 months of life standardized to WHO growth standards. Weight change was regressed on each of 168 metabolites (acylcarnitines, lysophosphatidylcholines, sphingomyelins, and amino acids). Metabolites significant after Bonferroni's correction were tested as predictors of later overweight/obesity. Among the overall 19 significant metabolites, 4 were associated with rapid growth and 15 were associated with a less-than-ideal weight change. After adjusting for feeding group, only the lysophosphatidylcholine LPCaC14:0 remained significantly associated with rapid weight gain (β = 0.18). Only LPCaC14:0 at age 6 months was predictive of overweight/obesity at age 6 years (OR 1.33; 95% CI 1.04-1.69). LPCa14:0 is strongly related to rapid growth in infancy and childhood overweight/obesity. This suggests that LPCaC14:0 levels may represent a metabolically programmed effect of infant weight gain on the later obesity risk. However, these results require confirmation by independent cohorts. © 2014 S. Karger AG, Basel.

  9. Should I Gain Weight?

    Science.gov (United States)

    ... Videos for Educators Search English Español Should I Gain Weight? KidsHealth / For Teens / Should I Gain Weight? ... something about it. Why Do People Want to Gain Weight? Some of the reasons people give for ...

  10. Teaching Knowledge Engineering: Experiences

    DEFF Research Database (Denmark)

    Andersen, Tom; Hartvig, Susanne C

    1998-01-01

    Includes description of experiences gained by teaching KE in construction domains. It outlines good starting points and overall guidance to education in applied AI.......Includes description of experiences gained by teaching KE in construction domains. It outlines good starting points and overall guidance to education in applied AI....

  11. Developmental gains in visuospatial memory predict gains in mathematics achievement.

    Directory of Open Access Journals (Sweden)

    Yaoran Li

    Full Text Available Visuospatial competencies are related to performance in mathematical domains in adulthood, but are not consistently related to mathematics achievement in children. We confirmed the latter for first graders and demonstrated that children who show above average first-to-fifth grade gains in visuospatial memory have an advantage over other children in mathematics. The study involved the assessment of the mathematics and reading achievement of 177 children in kindergarten to fifth grade, inclusive, and their working memory capacity and processing speed in first and fifth grade. Intelligence was assessed in first grade and their second to fourth grade teachers reported on their in-class attentive behavior. Developmental gains in visuospatial memory span (d = 2.4 were larger than gains in the capacity of the central executive (d = 1.6 that in turn were larger than gains in phonological memory span (d = 1.1. First to fifth grade gains in visuospatial memory and in speed of numeral processing predicted end of fifth grade mathematics achievement, as did first grade central executive scores, intelligence, and in-class attentive behavior. The results suggest there are important individual differences in the rate of growth of visuospatial memory during childhood and that these differences become increasingly important for mathematics learning.

  12. Developmental gains in visuospatial memory predict gains in mathematics achievement.

    Science.gov (United States)

    Li, Yaoran; Geary, David C

    2013-01-01

    Visuospatial competencies are related to performance in mathematical domains in adulthood, but are not consistently related to mathematics achievement in children. We confirmed the latter for first graders and demonstrated that children who show above average first-to-fifth grade gains in visuospatial memory have an advantage over other children in mathematics. The study involved the assessment of the mathematics and reading achievement of 177 children in kindergarten to fifth grade, inclusive, and their working memory capacity and processing speed in first and fifth grade. Intelligence was assessed in first grade and their second to fourth grade teachers reported on their in-class attentive behavior. Developmental gains in visuospatial memory span (d = 2.4) were larger than gains in the capacity of the central executive (d = 1.6) that in turn were larger than gains in phonological memory span (d = 1.1). First to fifth grade gains in visuospatial memory and in speed of numeral processing predicted end of fifth grade mathematics achievement, as did first grade central executive scores, intelligence, and in-class attentive behavior. The results suggest there are important individual differences in the rate of growth of visuospatial memory during childhood and that these differences become increasingly important for mathematics learning.

  13. Developmental Gains in Visuospatial Memory Predict Gains in Mathematics Achievement

    Science.gov (United States)

    Li, Yaoran; Geary, David C.

    2013-01-01

    Visuospatial competencies are related to performance in mathematical domains in adulthood, but are not consistently related to mathematics achievement in children. We confirmed the latter for first graders and demonstrated that children who show above average first-to-fifth grade gains in visuospatial memory have an advantage over other children in mathematics. The study involved the assessment of the mathematics and reading achievement of 177 children in kindergarten to fifth grade, inclusive, and their working memory capacity and processing speed in first and fifth grade. Intelligence was assessed in first grade and their second to fourth grade teachers reported on their in-class attentive behavior. Developmental gains in visuospatial memory span (d = 2.4) were larger than gains in the capacity of the central executive (d = 1.6) that in turn were larger than gains in phonological memory span (d = 1.1). First to fifth grade gains in visuospatial memory and in speed of numeral processing predicted end of fifth grade mathematics achievement, as did first grade central executive scores, intelligence, and in-class attentive behavior. The results suggest there are important individual differences in the rate of growth of visuospatial memory during childhood and that these differences become increasingly important for mathematics learning. PMID:23936154

  14. Detective quantum efficiency gains compared with speed gains for hypersensitized astronomical plates

    International Nuclear Information System (INIS)

    Kaye, A.L.

    1977-01-01

    It is reasonable to assume that gains in detective quantum efficiency (DQE) are far better criteria for assessing the performance of hypersensitizing techniques than gains in speed. It is shown here that gains in speed can be misleading, for some methods of hypersensitization give plates of increased speed but reduced detective quantum efficiency. (author)

  15. Design issues for a laboratory high gain fusion facility

    International Nuclear Information System (INIS)

    Hogan, W.J.

    1987-01-01

    In an inertial fusion laboratory high gain facility, experiments will be carried out with up to 1000 MJ of thermonuclear yield. The experiment area of such a facility will include many systems and structures that will have to operate successfully in the difficult environment created by the sudden large energy release. This paper estimates many of the nuclear effects that will occur, discusses the implied design issues and suggests possible solutions so that a useful experimental facility can be built. 4 figs

  16. Preventing Weight Gain

    Science.gov (United States)

    ... Local Programs Related Topics Diabetes Nutrition Preventing Weight Gain Language: English (US) Español (Spanish) Recommend on Facebook ... cancer. Choosing an Eating Plan to Prevent Weight Gain So, how do you choose a healthful eating ...

  17. Gain of a Smith-Purcell free-electron laser

    Directory of Open Access Journals (Sweden)

    H. L. Andrews

    2004-07-01

    Full Text Available A formula is derived for the small-signal gain of a Smith-Purcell free-electron laser. The theory describes the electron beam as a moving plasma dielectric, and assumes that the electron beam interacts with an evanescent mode traveling along the surface of a periodic waveguide with a rectangular profile. The phase velocity of the evanescent wave is synchronous with the electron velocity, but the group velocity is actually negative. The electron beam amplifies the evanescent wave, which does not itself radiate. According to this picture, the radiation observed emanating from the grating is Smith-Purcell radiation enhanced by the bunching of the electrons due to the interaction with the evanescent mode. There will also be radiation from the part of the evanescent mode that is outcoupled from the ends of the grating. This radiation appears at a lower frequency than the Smith-Purcell radiation. The new results explain both the gain and the radiation observed in the experiments of Urata and Walsh, and the cube-root current dependence of the gain inferred by Bakhtyari, Walsh, and Brownell.

  18. X-ray imaging with amorphous selenium: Pulse height measurements of avalanche gain fluctuations

    International Nuclear Information System (INIS)

    Lui, Brian J. M.; Hunt, D. C.; Reznik, A.; Tanioka, K.; Rowlands, J. A.

    2006-01-01

    Avalanche multiplication in amorphous selenium (a-Se) can provide a large, adjustable gain for active matrix flat panel imagers (AMFPI), enabling quantum noise limited x-ray imaging during both radiography and fluoroscopy. In the case of direct conversion AMFPI, the multiplication factor for each x ray is a function of its depth of interaction, and the resulting variations in gain can reduce the detective quantum efficiency (DQE) of the system. An experimental method was developed to measure gain fluctuations by analyzing images of individual x rays that were obtained using a video camera with an a-Se target operated in avalanche mode. Pulse height spectra (PHS) of the charge produced per x ray were recorded for monoenergetic 30.9, 49.4, and 73.8 keV x-ray sources. The rapid initial decay and long tail of each PHS can be explained by a model in which positive charge dominates the initiation of avalanche. The Swank information factor quantifies the effect of gain fluctuation on DQE and was calculated from the PHS. The information factor was found to be 0.5 for a 25 μm a-Se layer with a maximum gain of ∼300. Changing the energy of the incident x ray influenced the range of the primary photoelectron and noticeably affected the tail of the experimental PHS, but did not significantly change the avalanche Swank factor

  19. Student perception of travel service learning experience in Morocco.

    Science.gov (United States)

    Puri, Aditi; Kaddoura, Mahmoud; Dominick, Christine

    2013-08-01

    This study explores the perceptions of health profession students participating in academic service learning in Morocco with respect to adapting health care practices to cultural diversity. Authors utilized semi-structured, open-ended interviews to explore the perceptions of health profession students. Nine dental hygiene and nursing students who traveled to Morocco to provide oral and general health services were interviewed. After interviews were recorded, they were transcribed verbatim to ascertain descriptive validity and to generate inductive and deductive codes that constitute the major themes of the data analysis. Thereafter, NVIVO 8 was used to rapidly determine the frequency of applied codes. The authors compared the codes and themes to establish interpretive validity. Codes and themes were initially determined independently by co-authors and applied to the data subsequently. The authors compared the applied codes to establish intra-rater reliability. International service learning experiences led to perceptions of growth as a health care provider among students. The application of knowledge and skills learned in academic programs and service learning settings were found to help in bridging the theory-practice gap. The specific experience enabled students to gain an understanding of diverse health care and cultural practices in Morocco. Students perceived that the experience gained in international service learning can heighten awareness of diverse cultural and health care practices to foster professional growth of health professionals.

  20. JINR rapid communications

    International Nuclear Information System (INIS)

    1998-01-01

    The present collection of rapid communications from JINR, Dubna, contains seven separate records on relativistic multiparticle processes in the central rapidity region at asymptotically high energies, a new experimental study of charged K→3π decays, pre-Cherenkov radiation as a phenomenon of 'light barrier', stable S=-2 H dibaryon found in Dubna, calculation of Green functions and gluon top in some unambiguous gauges, a method of a fast selection of inelastic nucleus-nucleus collisions for the CMS experiment and the manifestation of jet quenching in differential distributions of the total transverse energy in nucleus-nucleus collisions

  1. Omega experiments and preparation for moderate-gain direct-drive experiments on Nif

    International Nuclear Information System (INIS)

    Mr Crory, R.L.; Bahr, R.E.; Boehly, T.R.

    2000-01-01

    Direct-drive laser-fusion ignition experiments rely on detailed understanding and control of irradiation uniformity, Rayleigh-Taylor instability, and target fabrication. LLE is investigating various theoretical aspects of a direct-drive NIF ignition target based on an 'all-DT' design: a spherical target of ∼ 3.5 mm diameter, 1 to 2 μm if CH wall thickness, and a ∼ 350 μm DT-ice layer near the triple point of DT (μ19K). OMEGA experiments are designed to address the critical issues related to direct-drive laser fusion and to provide the necessary data to validate the predictive capability of LLE computer codes. The future cryogenic targets used on OMEGA are hydrodynamically equivalent to those planned for the NIF. The current experimental studies on OMEGA address all of the essential components of direct-drive laser fusion: irradiation uniformity and laser imprinting, Rayleigh-Taylor growth and saturation, compressed core performance and shell-fuel mixing, laser-plasma interactions and their effect on target performance, and cryogenic target fabrication and handling. (authors)

  2. Infant weight gain and adolescent body mass index: comparison across two British cohorts born in 1946 and 2001.

    Science.gov (United States)

    Johnson, William; Bann, David; Hardy, Rebecca

    2018-04-19

    To investigate how the relationship of infant weight gain with adolescent body mass index (BMI) differs for individuals born during and before the obesity epidemic era. Data from two British birth cohorts, the 1946 National Survey of Health and Development (NSHD, n=4199) and the 2001 Millennium Cohort Study (MCS, n=9417), were used to estimate and compare associations of infant weight gain between ages 0 and 3 years with adolescent outcomes. BMI Z-scores and overweight/obesity at ages 11 and 14 years. Infant weight gain, in Z-scores, was positively associated with adolescent BMI Z-scores in both cohorts. Non-linearity in the MCS meant that associations were only stronger than in the NSHD when infant weight gain was above -1 Z-score. Using decomposition analysis, between-cohort differences in association accounted for 20%-30% of the differences (secular increases) in BMI Z-scores, although the underlying estimates were not precise with 95% CIs crossing 0. Conversely, between-cohort differences in the distribution of infant weight gain accounted for approximately 9% of the differences (secular increases) in BMI Z-scores, and the underlying estimates were precise with 95% CI not crossing 0. Relative to normal weight gain (change of -0.67 to +0.67 Z-scores between ages 0 and 3 years), very rapid infant weight gain (>1.34), but not rapid weight gain (+0.67 to +1.34), was associated with higher BMI Z-scores more strongly in the MCS (β=0.790; 95% CI 0.717 to 0.862 at age 11 years) than in the NSHD (0.573; 0.466 to 0.681) (pgain (gain was not, however, more strongly associated with increased risk of adolescent overweight/obesity or thinness, respectively, in the more recently born cohort. Greater infant weight gain, at the middle/upper end of the distribution, was more strongly associated with higher adolescent BMI among individuals born during (compared with before) the obesity epidemic. Combined with a secular change towards greater infant weight gain, these

  3. Influences of finite gain bandwidth on pulse propagation in parabolic fiber amplifiers with distributed gain profiles

    International Nuclear Information System (INIS)

    Zhao Jia-Sheng; Li Pan; Chen Xiao-Dong; Feng Su-Juan; Mao Qing-He

    2012-01-01

    The evolutions of the pulses propagating in decreasing and increasing gain distributed fiber amplifiers with finite gain bandwidths are investigated by simulations with the nonlinear Schrödinger equation. The results show that the parabolic pulse propagations in both the decreasing and the increasing gain amplifiers are restricted by the finite gain bandwidth. For a given input pulse, by choosing a small initial gain coefficient and gain variation rate, the whole gain for the pulse amplification limited by the gain bandwidth may be higher, which is helpful for the enhancement of the output linearly chirped pulse energy. Compared to the decreasing gain distributed fiber amplifier, the increasing gain distributed amplifier may be more conducive to suppress the pulse spectral broadening and increase the critical amplifier length for achieving a larger output linearly chirped pulse energy

  4. Evaluation of a nationwide mass media campaign aimed at prevention of weight gain in Dutch young adults

    NARCIS (Netherlands)

    B.M. Wammes (Birgitte)

    2007-01-01

    textabstractThe prevalence of overweight and obesity is increasing rapidly. In the Netherlands, the prevalence of obesity has roughly doubled over the last decade and now more than 40% of the Dutch adult population is overweight and more than 10% obese. To promote weight-gain preventive actions

  5. Measurement of amplitude fluctuations in a rapid response photomultiplier

    International Nuclear Information System (INIS)

    Raimbault, P.

    1961-01-01

    In order to measure amplitude fluctuations in a rapid response photomultiplier, two independent random variables are introduced which determine the shape of the anode pulse. The energy of each pulse, which depends directly on the gain and the variance, is the first variable; amplitude fluctuations, functions of the first variable, depend as well on the pulse width which in turn constitutes the second variable. The results obtained on the variations of the maximum impulse, using a steep-edged pulse broadening circuit, and those obtained on the statistical variations of the gain, are compared to show that the variance relative to the maximum amplitude of the signal is greater than that of the gain. Within the limits of these fluctuations are shown the contribution of the secondary emission coefficient of the first dynode, and that of the mean secondary emission coefficient of the multiplier. (author) [fr

  6. Rapid detox: understanding new treatment approaches for the addicted patient.

    Science.gov (United States)

    McCabe, S

    2000-01-01

    Despite substantive advances in understanding of genetic and biochemical basis of substance abuse and addiction in the last decade, little information has been translated into alternative treatment models for the addicted patient. Rapid detox, an alternative form of detox treatment, is gaining in both acceptance and popularity. To increase readers' understanding of the neurobiology of addiction and the mode of action of new detox approaches for patients addicted to opiate drugs. A review of the current literature pertaining to rapid detox. Rapid detox is a viable alternative for selected patients attempting to detox from opiate agents of abuse. Increasing knowledge of new treatment approaches allows nurses working to assist addicted patients in planning and receiving treatment based on new awareness of the neurobiology of addiction.

  7. Brand Experience in Banking Industry: Direct and Indirect Relationship to Loyalty

    Directory of Open Access Journals (Sweden)

    Nuri WULANDARI

    2016-02-01

    Full Text Available In marketing, the meaning of value is rapidly shifting from service and relationships to experiences. It is believed that the traditional value proposition is no longer effective to compete in the market and to gain customer loyalty. By adapting the brand experience model, this study tries to validate the model in the banking industry, which is currently facing intense competition to retain customers. The brand experience construct is tested for its direct and indirect relationship toward loyalty. It is postulated that satisfaction and brand authenticity might be instrumental in mediating brand experience to loyalty. Research was conducted via in-depth interview and quantitative survey, targeting bank customers in Jakarta. The result confirmed that brand experience has direct and indirect contribution to loyalty in significant and positive manner. The research contributes in validating previous studies with a rare emphasis in banking sector. The result implies that brand experience is an important value to lead to customer loyalty in this area and subject to growing research on experience marketing.

  8. RapidEye constellation relative radiometric accuracy measurement using lunar images

    Science.gov (United States)

    Steyn, Joe; Tyc, George; Beckett, Keith; Hashida, Yoshi

    2009-09-01

    The RapidEye constellation includes five identical satellites in Low Earth Orbit (LEO). Each satellite has a 5-band (blue, green, red, red-edge and near infrared (NIR)) multispectral imager at 6.5m GSD. A three-axes attitude control system allows pointing the imager of each satellite at the Moon during lunations. It is therefore possible to image the Moon from near identical viewing geometry within a span of 80 minutes with each one of the imagers. Comparing the radiometrically corrected images obtained from each band and each satellite allows a near instantaneous relative radiometric accuracy measurement and determination of relative gain changes between the five imagers. A more traditional terrestrial vicarious radiometric calibration program has also been completed by MDA on RapidEye. The two components of this program provide for spatial radiometric calibration ensuring that detector-to-detector response remains flat, while a temporal radiometric calibration approach has accumulated images of specific dry dessert calibration sites. These images are used to measure the constellation relative radiometric response and make on-ground gain and offset adjustments in order to maintain the relative accuracy of the constellation within +/-2.5%. A quantitative comparison between the gain changes measured by the lunar method and the terrestrial temporal radiometric calibration method is performed and will be presented.

  9. Polymerase Chain Reaction/Rapid Methods Are Gaining a Foothold in Developing Countries.

    Science.gov (United States)

    Ragheb, Suzan Mohammed; Jimenez, Luis

    Detection of microbial contamination in pharmaceutical raw materials and finished products is a critical factor to guarantee their safety, stability, and potency. Rapid microbiological methods-such as polymerase chain reaction-have been widely applied to clinical and food quality control analysis. However, polymerase chain reaction applications to pharmaceutical quality control have been rather slow and sporadic. Successful implementation of these methods in pharmaceutical companies in developing countries requires important considerations to provide sensitive and robust assays that will comply with good manufacturing practices. In recent years several publications have encouraged the application of molecular techniques in the microbiological assessment of pharmaceuticals. One of these techniques is polymerase chain reaction (PCR). The successful application of PCR in the pharmaceutical industry in developing countries is governed by considerable factors and requirements. These factors include the setting up of a PCR laboratory and the choice of appropriate equipment and reagents. In addition, the presence of well-trained analysts and establishment of quality control and quality assurance programs are important requirements. The pharmaceutical firms should take into account these factors to allow better chances for regulatory acceptance and wide application of this technique. © PDA, Inc. 2014.

  10. Cognitive-Behavioral Therapy for Rapid Cycling Bipolar Disorder

    Science.gov (United States)

    Reilly-Harrington, Noreen A.; Knauz, Robert O.

    2005-01-01

    This article describes the application of cognitive-behavioral therapy (CBT) to the treatment of rapid cycling bipolar disorder. Between 10% and 24% of bipolar patients experience a rapid cycling course, with 4 or more mood episodes occurring per year. Characterized by nonresponse to standard mood-stabilizing medications, rapid cyclers are…

  11. Increase in H-reflex gain following 1 week of immobilization

    DEFF Research Database (Denmark)

    Jensen, Jesper Lundbye; Sørensen, Mie; Nielsen, Jens Bo

    It is well established that motor experience induces structural and functional plasticity within the central nervous system. It is less well investigated whether reduced motor activity in relation to immobilization is also associated with plastic neuronal changes. The present experiment examined ...... removal all measurements had returned to preimmobilization levels. These results show that immobilization of only one week duration is associated with reversible adaptive changes in the gain of the central part of the monosynaptic stretch reflex....

  12. Rapid-cycle testing cuts bed turnaround by 85%.

    Science.gov (United States)

    2004-11-01

    You can use rapid-cycle testing to try out new approaches to overcrowding much more frequently than with more traditional process improvement strategies. Improving bed turnaround notification can yield dramatic improvements. Telling staff they have to try a new process only for three days makes it easier to gain buy-in. Look for old policies that are no longer needed, yet continue to keep your staff bogged down.

  13. High gain L-band erbium-doped fiber amplifier with two-stage ...

    Indian Academy of Sciences (India)

    stage erbium-doped fiber amplifier; amplified spontaneous emission. Abstract. An experiment on gain enhancement in the long wavelength band erbium-doped fiber amplifier (L-band EDFA) is demonstrated using dual forward pumping scheme ...

  14. Ultrafast Gain Dynamics in Quantum Dot Amplifiers: Theoretical Analysis and Experimental Investigations

    DEFF Research Database (Denmark)

    Poel, Mike van der; Gehrig, Edeltraud; Hess, Ortwin

    2005-01-01

    Ultrafast gain dynamics in an optical amplifier with an active layer of self-organized quantum dots (QDs) emitting near 1.3$muhbox m$is characterized experimentally in a pump-probe experiment and modeled theoretically on the basis of QD Maxwell–Bloch equations. Experiment and theory are in good......$factor) is theoretically predicted and demonstrated in the experiments. The fundamental analysis reveals the underlying physical processes and indicates limitations to QD-based devices....

  15. Experiment study on the thick GEM-like multiplier for X-ray photoelectrons energy deposition gaining

    International Nuclear Information System (INIS)

    Zhu Pengfei; Ye Yan; Long Yan; Cao Ningxiang; Jia Xing; Li Jianfeng

    2009-01-01

    The GEM is a novel detector with high gain,high time and location resolution. Imitating the structure of the GEM, a thick GEM-like multiplier which has the similar function with that of the GEM is designed and manufactured. The characteristics of the thick GEM-like multiplier increasing electron energy deposition in absorbing medium has been experimentally studied. The results indicate that the energy deposition gain of x-ray photoelectron in medium is apparent, and the maximum energy deposition can increase by more than 40%. Some suggestions of further increasing the energy deposition are given, and the future application of the way of increasing the x-ray photoelectron energy deposition by the thick GEM-like multiplier in hard x-ray imaging is prospected. (authors)

  16. Experience gained with energy taxes in Europe - Lessons for Switzerland; Erfahrungen mit Energiesteuern in Europa. Lehren fuer die Schweiz

    Energy Technology Data Exchange (ETDEWEB)

    Peter, M.; Lueckge, H.; Iten, R.; Trageser, J. [Infras, Zuerich (Switzerland); Goerlach, B.; Blobel, D.; Kraemer, A. [Ecologic Institut fuer Internationale und Europaeische Umweltpolitik, Berlin (Germany)

    2007-12-15

    This comprehensive final report for the Swiss Federal Office of Energy (SFOE) takes a look at experience gained with energy taxes in Europe and the lessons that can be learned for Switzerland. The variety of energy and CO{sub 2} taxes that have been introduced in Europe since the early 1990s is reviewed. These are intended to reduce energy consumption and CO{sub 2} emissions and complement conventional mineral oil taxes. Some of these non-fiscal energy and CO{sub 2} taxes that have been created within the scope of the EU directive on energy taxation are examined and commented on, as is their impact on energy consumption. The situation in EU member states is described and commented on. Success-factors and general conditions are examined and conclusions that can be drawn for Switzerland are examined.

  17. EGRET Unidentified Source Radio Observations and Performance of Receiver Gain Calibration

    International Nuclear Information System (INIS)

    Niinuma, Kotaro; Asuma, Kuniyuki; Kuniyoshi, Masaya; Matsumura, Nobuo; Takefuji, Kazuhiro; Kida, Sumiko; Takeuchi, Akihiko; Ichikawa, Hajime; Sawano, Akihiro; Yoshimura, Naoya; Suzuki, Shigehiro; Nakamura, Ryosuke; Nakayama, Yu; Daishido, Tsuneaki

    2006-01-01

    Last year, we have developed the receiver gain calibration system by using Johnson-Nyquist noise, for accuracy flux measurement, because we have been starting radio identification program of transient radio sources, blazars and radio counterpart of The Energetic Gamma Ray Experiment Telescope (EGRET) unidentified γ-ray sources in Waseda Nasu Pulsar Observatory. It is shown that there are a few low correlation data between receiver gain and ambient temperature around receiver for anything troubles of receiver, because we can detect gain and ambient temperature through a day by developed system. Estimated fluctuations of daily data of steady sources decrease by removing low correlation data before analysing. As the result of our analysis by using above system, radio counterpart of EGRET identified source showed fading light-curve for a week

  18. Genetic parameters and estimated genetic gains in young rubber tree progenies

    Directory of Open Access Journals (Sweden)

    Cecília Khusala Verardi

    2013-04-01

    Full Text Available The objective of this work was to assess the genetic parameters and to estimate genetic gains in young rubber tree progenies. The experiments were carried out during three years, in a randomized block design, with six replicates and ten plants per plot, in three representative Hevea crop regions of the state of São Paulo, Brazil. Twenty-two progenies were evaluated, from three to five years old, for rubber yield and annual girth growth. Genetic gain was estimated with the multi-effect index (MEI. Selection by progenies means provided greater estimated genetic gain than selection based on individuals, since heritability values of progeny means were greater than the ones of individual heritability, for both evaluated variables, in all the assessment years. The selection of the three best progenies for rubber yield provided a selection gain of 1.28 g per plant. The genetic gains estimated with MEI using data from early assessments (from 3 to 5-year-old were generally high for annual girth growth and rubber yield. The high genetic gains for annual girth growth in the first year of assessment indicate that progenies can be selected at the beginning of the breeding program. Population effective size was consistent with the three progenies selected, showing that they were not related and that the population genetic variability is ensured. Early selection with the genetic gains estimated by MEI can be made on rubber tree progenies.

  19. Active rc filter permits easy trade-off of amplifier gain and sensitivity to gain

    Science.gov (United States)

    Kerwin, W. J.; Shaffer, C. V.

    1968-01-01

    Passive RC network was designed with zeros of transmission in the right half of the complex frequency plane in the feedback loop of a simple negative-gain amplifier. The proper positioning provides any desired trade-off between amplifier gain and sensitivity to amplifier gain.

  20. Gain uniformity, linearity, saturation and depletion in gated microchannel-plate x-ray framing cameras

    International Nuclear Information System (INIS)

    Landen, O.L.; Bell, P.M.; Satariano, J.J.; Oertel, J.A.; Bradley, D.K.

    1994-01-01

    The pulsed characteristics of gated, stripline configuration microchannel-plate (MCP) detectors used in X-ray framing cameras deployed on laser plasma experiments worldwide are examined in greater detail. The detectors are calibrated using short (20 ps) and long (500 ps) pulse X-ray irradiation and 3--60 ps, deep UV (202 and 213 nm), spatially-smoothed laser irradiation. Two-dimensional unsaturated gain profiles show 5 in irradiation and fitted using a discrete dynode model. Finally, a pump-probe experiment quantifying for the first time long-suspected gain depletion by strong localized irradiation was performed. The mechanism for the extra voltage and hence gain degradation is shown to be associated with intense MCP irradiation in the presence of the voltage pulse, at a fluence at least an order of magnitude above that necessary for saturation. Results obtained for both constant pump area and constant pump fluence are presented. The data are well modeled by calculating the instantaneous electrical energy loss due to the intense charge extraction at the pump site and then recalculating the gain downstream at the probe site given the pump-dependent degradation in voltage amplitude

  1. Polygenic Risk, Appetite Traits, and Weight Gain in Middle Childhood: A Longitudinal Study.

    Science.gov (United States)

    Steinsbekk, Silje; Belsky, Daniel; Guzey, Ismail Cuneyt; Wardle, Jane; Wichstrøm, Lars

    2016-02-01

    Genome-wide association studies have identified genetic risks for obesity. These genetic risks influence development of obesity partly by accelerating weight gain in childhood. Research is needed to identify mechanisms to inform intervention. Cross-sectional studies suggest appetite traits as a candidate mechanism. Longitudinal studies are needed to test whether appetite traits mediate genetic influences on children's weight gain. To test whether genetic risk for obesity predicts accelerated weight gain in middle childhood (ages 4-8 years) and whether genetic association with accelerated weight gain is mediated by appetite traits. Longitudinal study of a representative birth cohort at the Trondheim Early Secure Study, Trondheim, Norway, enrolled at age 4 years during 2007 to 2008, with follow-ups at ages 6 and 8 years. Participants were sampled from all children born in 2003 or 2004 who attended regular community health checkups for 4-year-olds (97.2% attendance; 82.0% consent rate, n = 2475). Nine hundred ninety-five children participated at age 4 years, 795 at age 6 years, and 699 at age 8 years. Analyses included 652 children with genotype, adiposity, and appetite data. Outcomes were body mass index and body-fat phenotypes measured from anthropometry (ages 4, 6, and 8 years) and bioelectrical impedance (ages 6 and 8 years). Genetic risk for obesity was measured using a genetic risk score composed of 32 single-nucleotide polymorphisms previously discovered in genome-wide association studies of adult body mass index. Appetite traits were measured at age 6 years with the Children's Eating Behavior Questionnaire. Of the 652 genotyped child participants, 323 (49.5%) were female, 58 (8.9%) were overweight, and 1 (0.2%) was obese. Children at higher genetic risk for obesity had higher baseline body mass index and fat mass compared with lower genetic risk peers, and they gained weight and fat mass more rapidly during follow-up. Each SD increase in genetic risk score was

  2. An output amplitude configurable wideband automatic gain control with high gain step accuracy

    International Nuclear Information System (INIS)

    He Xiaofeng; Ye Tianchun; Mo Taishan; Ma Chengyan

    2012-01-01

    An output amplitude configurable wideband automatic gain control (AGC) with high gain step accuracy for the GNSS receiver is presented. The amplitude of an AGC is configurable in order to cooperate with baseband chips to achieve interference suppression and be compatible with different full range ADCs. And what's more, the gain-boosting technology is introduced and the circuit is improved to increase the step accuracy. A zero, which is composed by the source feedback resistance and the source capacity, is introduced to compensate for the pole. The AGC is fabricated in a 0.18 μm CMOS process. The AGC shows a 62 dB gain control range by 1 dB each step with a gain error of less than 0.2 dB. The AGC provides 3 dB bandwidth larger than 80 MHz and the overall power consumption is less than 1.8 mA, and the die area is 800 × 300 μm 2 . (semiconductor integrated circuits)

  3. Weak effect of ion cyclotron acceleration on rapidly chirping beam-driven instabilities in the National Spherical Torus Experiment

    International Nuclear Information System (INIS)

    Heidbrink, W W; Ruskov, E; Fredrickson, E D; Gorelenkov, N; Medley, S S; Berk, H L; Harvey, R W

    2006-01-01

    The fast-ion distribution function in the National Spherical Torus Experiment is modified from shot to shot while keeping the total injected power at ∼2 MW. Deuterium beams of different energy and tangency radius are injected into helium L-mode plasmas, producing a rich set of instabilities, including compressional Alfven eigenmodes, toroidicity-induced Alfven eigenmodes (TAE), 50-100 kHz instabilities with rapid frequency sweeps or chirps, and strong, low frequency (10-20 kHz) fishbones. The experiment was motivated by a theory that attributes frequency chirping to the formation of holes and clumps in phase-space. In the theory, increasing the effective collision frequency of the fast ions that drive the instability can suppress frequency chirping. In the experiment, high-power (∼<3 MW) high harmonic fast wave (HHFW) heating accelerates the fast ions in an attempt to alter the nonlinear dynamics. Steady-frequency TAE modes diminish during the HHFW heating but there is little evidence that frequency chirping is suppressed

  4. Weak effect of ion cyclotron acceleration on rapidly chirping beam-driven instabilities in the National Spherical Torus Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Heidbrink, W W [University of California, Irvine, California (United States); Ruskov, E [University of California, Irvine, California (United States); Fredrickson, E D [Princeton Plasma Physics Laboratory, Princeton, New Jersey (United States); Gorelenkov, N [Princeton Plasma Physics Laboratory, Princeton, New Jersey (United States); Medley, S S [Princeton Plasma Physics Laboratory, Princeton, New Jersey (United States); Berk, H L [University of Texas, Austin, Texas (United States); Harvey, R W [CompX, Del Mar, California (United States)

    2006-09-15

    The fast-ion distribution function in the National Spherical Torus Experiment is modified from shot to shot while keeping the total injected power at {approx}2 MW. Deuterium beams of different energy and tangency radius are injected into helium L-mode plasmas, producing a rich set of instabilities, including compressional Alfven eigenmodes, toroidicity-induced Alfven eigenmodes (TAE), 50-100 kHz instabilities with rapid frequency sweeps or chirps, and strong, low frequency (10-20 kHz) fishbones. The experiment was motivated by a theory that attributes frequency chirping to the formation of holes and clumps in phase-space. In the theory, increasing the effective collision frequency of the fast ions that drive the instability can suppress frequency chirping. In the experiment, high-power ({approx}<3 MW) high harmonic fast wave (HHFW) heating accelerates the fast ions in an attempt to alter the nonlinear dynamics. Steady-frequency TAE modes diminish during the HHFW heating but there is little evidence that frequency chirping is suppressed.

  5. Weak effect of ion cyclotron acceleration on rapidly chirping beam-driven instabilities in the National Spherical Torus Experiment

    Energy Technology Data Exchange (ETDEWEB)

    W W,Heidbrink; E,Ruskov; E D,Fredrickson; N,Gorelenkov; S S,Medley; H L,Berk; R W,Harvey

    2006-09-01

    The fast-ion distribution function in the National Spherical Torus Experiment is modified from shot to shot while keeping the total injected power at ~2 MW. Deuterium beams of different energy and tangency radius are injected into helium L-mode plasmas, producing a rich set of instabilities, including compressional Alfven eigenmodes, toroidicity-induced Alfven eigenmodes (TAE), 50–100 kHz instabilities with rapid frequency sweeps or chirps, and strong, low frequency (10–20 kHz) fishbones. The experiment was motivated by a theory that attributes frequency chirping to the formation of holes and clumps in phase-space. In the theory, increasing the effective collision frequency of the fast ions that drive the instability can suppress frequency chirping. In the experiment, high-power (≤3MW) high harmonic fast wave (HHFW) heating accelerates the fast ions in an attempt to alter the nonlinear dynamics. Steady-frequency TAE modes diminish during the HHFW heating but there is little evidence that frequency chirping is suppressed.

  6. Clinical undergraduate training and assessment in primary health care: Experiences gained from Crete, Greece

    Directory of Open Access Journals (Sweden)

    Fioretos Michael

    2005-05-01

    Full Text Available Abstract Background Primary Health Care (PHC is increasingly being introduced into undergraduate medical education. In Greece, the Faculty of Medicine of the University of Crete was the first to introduce a 4-week long training in primary health care. This paper presents the experiences gained from the initial implementation of the teaching of practice-based primary care in rural Crete and reports on the assessment scale that was developed. Methods 284 students' case write-ups from the 6 primary care units (PCUs where they were allocated for the period 1990 to 1994 were analysed. The demographic data of the students and patients and the number of home visits were studied. Content analysis of the students' write-ups was carried out, using an assessment scale consisting of 10 dichotomous variables, in order to quantify eight (8 primary qualitative criteria. Results Internal reliability was estimated by the index KR20 = 0.67. Face and content validity was found to conform to the standards set for the course, while logistic linear regression analysis showed that the quality criteria could be used as an assessment scale. The number of home visits carried out varied between the various different PCUs (p Conclusion The primary health care course achieved the objectives of introducing students to comprehensive, community oriented care, although there was variation between the PCUs. The assessment scale that was developed to analyse the case-write ups of the students provided data that can be used to evaluate the course.

  7. The Impact of Kangaroo Care on Premature Infant Weight Gain.

    Science.gov (United States)

    Evereklian, Melvina; Posmontier, Bobbie

    Preterm births occur among 11.4% of all live infant births. Without steady weight gain, premature infants may experience lengthy hospitalizations, neurodevelopmental deficits and hospital readmissions, which can increase the financial burden on the health care system and their families. The total U.S. health-related costs linked to preterm infant deliveries are estimated at $4.33 billion. Kangaroo care is a feasible practice that can improve preterm infant weight gain. However, this intervention is utilized less often throughout the U.S. due to numerous barriers including a lack of consistent protocols, inadequate knowledge, and decreased level of confidence in demonstrating the proper kangarooing technique. An integrative review was conducted to evaluate the impact of kangaroo care on premature infant weight gain in order to educate nurses about its efficacy among preterm infants. A literature search was conducted using CINAHL, PubMed, Cochrane Reviews, ClinicalKey and Google Scholar. Large volume searches were restricted using appropriate filters and limiters. Most of the evaluated studies determined that weight gain was greater among the kangarooing premature infants. Kangaroo care is a low-tech low-cost modality that can facilitate improved preterm infant weight gain even in low-resource settings. Despite its current efficacy, kangaroo care is not widely utilized due to several barriers including an absence of standardized protocols and a lack of knowledge about its benefits. Kangaroo care can become a widespread formalized practice after nurses and parents learn about the technique and its numerous benefits for premature infants, including its association with improved weight gain. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Design and Experiment of Nonlinear Observer with Adaptive Gains for Battery State of Charge Estimation

    Directory of Open Access Journals (Sweden)

    Linhui Zhao

    2017-12-01

    Full Text Available State of charge (SOC is an important evaluation index for lithium-ion batteries (LIBs in electric vehicles (EVs. This paper proposes a nonlinear observer with a new adaptive gain structure for SOC estimation based on a second-order RC model. It is able to dynamically adjust the gains and obtain a better balance between convergence speed and estimation accuracy with less computational time. A sufficient condition is derived to guarantee the uniform asymptotic stability of the observer, and its robustness with respect to disturbances and uncertainties is analyzed with the help of input-to-state stability (ISS theory. A selection guide of the observer gains in practical application is presented. The estimation accuracy and convergence rate of the observer are evaluated and compared with those of extended Kalman filter (EKF based on multi-temperature datasets from two different types of LIB cells. The robustness against different disturbances and uncertainties that may appear in a real vehicle is validated and discussed in detail. The experimental results show that the proposed observer is capable of achieving better performance with less computational time in comparison to EKF for different types of LIB cells under various working conditions. The observer is also capable of estimating SOC accurately for real life conditions according to the validation results of datasets from a battery management system (BMS in an EV battery pack. Furthermore, the observer is simple enough, and is suitable for implementation on embedded hardware for LIB cells of EVs.

  9. Prior exercise training blunts short-term high-fat diet-induced weight gain.

    Science.gov (United States)

    Snook, Laelie A; MacPherson, Rebecca E K; Monaco, Cynthia M F; Frendo-Cumbo, Scott; Castellani, Laura; Peppler, Willem T; Anderson, Zachary G; Buzelle, Samyra L; LeBlanc, Paul J; Holloway, Graham P; Wright, David C

    2016-08-01

    High-fat diets rapidly cause weight gain and glucose intolerance. We sought to determine whether these changes could be mitigated with prior exercise training. Male C57BL/6J mice were exercise-trained by treadmill running (1 h/day, 5 days/wk) for 4 wk. Twenty-four hours after the final bout of exercise, mice were provided with a high-fat diet (HFD; 60% kcal from lard) for 4 days, with no further exercise. In mice fed the HFD prior to exercise training, the results were blunted weight gain, reduced fat mass, and a slight attenuation in glucose intolerance that was mirrored by greater insulin-induced Akt phosphorylation in skeletal muscle compared with sedentary mice fed the HFD. When ad libitum-fed sedentary mice were compared with sedentary high-fat fed mice that were calorie restricted (-30%) to match the weight gain of the previously trained high-fat fed mice, the same attenuated impairments in glucose tolerance were found. Blunted weight gain was associated with a greater capacity to increase energy expenditure in trained compared with sedentary mice when challenged with a HFD. Although mitochondrial enzymes in white adipose tissue and UCP-1 protein content in brown adipose tissue were increased in previously exercised compared with sedentary mice fed a HFD, ex vivo mitochondrial respiration was not increased in either tissue. Our data suggest that prior exercise training attenuates high-fat diet-induced weight gain and glucose intolerance and is associated with a greater ability to increase energy expenditure in response to a high-fat diet. Copyright © 2016 the American Physiological Society.

  10. Automatic gain control of neural coupling during cooperative hand movements.

    Science.gov (United States)

    Thomas, F A; Dietz, V; Schrafl-Altermatt, M

    2018-04-13

    Cooperative hand movements (e.g. opening a bottle) are controlled by a task-specific neural coupling, reflected in EMG reflex responses contralateral to the stimulation site. In this study the contralateral reflex responses in forearm extensor muscles to ipsilateral ulnar nerve stimulation was analyzed at various resistance and velocities of cooperative hand movements. The size of contralateral reflex responses was closely related to the level of forearm muscle activation required to accomplish the various cooperative hand movement tasks. This indicates an automatic gain control of neural coupling that allows a rapid matching of corrective forces exerted at both sides of an object with the goal 'two hands one action'.

  11. Weight Gain during Pregnancy

    Science.gov (United States)

    ... Global Map Premature Birth Report Cards Careers Archives Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal ... fitness > Weight gain during pregnancy Weight gain during pregnancy E-mail to a friend Please fill in ...

  12. Rapid binge-like eating and body weight gain driven by zona incerta GABA neuron activation.

    Science.gov (United States)

    Zhang, Xiaobing; van den Pol, Anthony N

    2017-05-26

    The neuronal substrate for binge eating, which can at times lead to obesity, is not clear. We find that optogenetic stimulation of mouse zona incerta (ZI) γ-aminobutyric acid (GABA) neurons or their axonal projections to paraventricular thalamus (PVT) excitatory neurons immediately (in 2 to 3 seconds) evoked binge-like eating. Minimal intermittent stimulation led to body weight gain; ZI GABA neuron ablation reduced weight. ZI stimulation generated 35% of normal 24-hour food intake in just 10 minutes. The ZI cells were excited by food deprivation and the gut hunger signal ghrelin. In contrast, stimulation of excitatory axons from the parasubthalamic nucleus to PVT or direct stimulation of PVT glutamate neurons reduced food intake. These data suggest an unexpected robust orexigenic potential for the ZI GABA neurons. Copyright © 2017, American Association for the Advancement of Science.

  13. Gain monitoring of telescope array photomultiplier cameras for the first 4 years of operation

    Energy Technology Data Exchange (ETDEWEB)

    Shin, B.K., E-mail: bkshin@hanyang.ac.kr [Hanyang University, Seongdong-gu, Seoul (Korea, Republic of); Tokuno, H.; Tsunesada, Y. [Tokyo Institute of Technology, Meguro, Tokyo (Japan); Abu-Zayyad, T. [University of Utah, High Energy Astrophysics Institute, Salt Lake City, UT (United States); Aida, R. [University of Yamanashi, Interdisciplinary Graduate School of Medicine and Engineering, Kofu, Yamanashi (Japan); Allen, M.; Anderson, R. [University of Utah, High Energy Astrophysics Institute, Salt Lake City, UT (United States); Azuma, R. [Tokyo Institute of Technology, Meguro, Tokyo (Japan); Barcikowski, E.; Belz, J.W.; Bergman, D.R.; Blake, S.A.; Cady, R. [University of Utah, High Energy Astrophysics Institute, Salt Lake City, UT (United States); Cheon, B.G., E-mail: bgcheon@hanyang.ac.kr [Hanyang University, Seongdong-gu, Seoul (Korea, Republic of); Chiba, J. [Tokyo University of Science, Noda, Chiba (Japan); Chikawa, M. [Kinki University, Higashi Osaka, Osaka (Japan); Cho, E.J. [Hanyang University, Seongdong-gu, Seoul (Korea, Republic of); Cho, W.R. [Yonsei University, Seodaemun-gu, Seoul (Korea, Republic of); Fujii, H. [Institute of Particle and Nuclear Studies, KEK, Tsukuba, Ibaraki (Japan); Fujii, T. [Osaka City University, Osaka, Osaka (Japan); and others

    2014-12-21

    The stability of the gain of the photomultiplier (PMT) camera for the Fluorescence Detector (FD) of the Telescope Array experiment was monitored using an {sup 241}Am loaded scintillator pulsers (YAP) and a diffused xenon flasher (TXF) for a selected set of 35 PMT-readout channels. From the monitoring of YAP pulses over four years of FD operation, we found slow monotonic drifts of PMT gains at a rate of −1.7∼+1.7%/year. An average of the PMT gains over the 35 channels stayed nearly constant with a rate of change measured at −0.01±0.31(stat)±0.21(sys)%/year. No systematic decrease of the PMT gain caused by the night sky background was observed. Monitoring by the TXF also tracked the PMT gain drift of the YAP at 0.88±0.14(stat)%/year.

  14. Human capital in European peripheral regions: brain - drain and brain - gain

    NARCIS (Netherlands)

    Coenen, Franciscus H.J.M.

    2004-01-01

    Project goal - The overall goal of the project is to build a legitimate transnational network to transfer ideas and experiences and implement measures to reduce brain drain and foster brain gain while reinforcing the economical and spatial development of peripheral regions in NWE. This means a

  15. First Aid and Transportation Course Contents Based on Experience gained in the Iran-Iraq War: a Qualitative Study.

    Science.gov (United States)

    Sarhangi, Forogh; Gholami, Hamid Reza; Khaghanizade, Morteza; Najafi Mehri, Soheil

    2015-02-01

    Effective first aid and transportation influences injury-induced mortality. But few qualitative studies have been conducted so far in this area. The aim of this study was to identify the content of the first aid and patient transportation course based on experience gained from the Iran-Iraq war. This was a conventional qualitative content analysis study; a purposeful sample of 14 first aid and transportation experts who had worked during the Iran-Iraq war was recruited. We collected and analyzed the study data by using the semi-structured interview method and the conventional content analysis approach respectively. Each interview transcript was reviewed several times. Words, sentences, and paragraphs were labeled with codes. Codes were compared with each other and categorized according to their similarities. Similar sub-categories and categories were also grouped together and formed themes. Study participants' experiences of wartime first aid and transportation (FAT) education fell into two main themes including 'the congruence of education and educational needs' and 'managers' engagement in FAT education. The four main categories of these two themes were use of appropriate educational facilities, adopting effective teaching strategies, universal FAT education and specialized training skills. The two key requirements of the first aid and transportation courses are practicality and managerial engagement. We developed and provided specific guidance of FAT curriculum by using the study findings. This curriculum is recommended for educating FAT staffs, paramedics, emergency technicians, and military nurses.

  16. Rapid Wall-Breaching Kit, Ingress Hole Determination Experiment

    National Research Council Canada - National Science Library

    Turner, Daniel D; Carstens, Christian B; Redden, Elizabeth S; Whalen, Joseph B

    2003-01-01

    .... The experiment was conducted at McKenna Military Operations in Urban Terrain (MOUT) site Ft. Benning, Georgia. Soldiers from the Ranger Training Brigade and Headquarters Company 3/11th Infantry participated in the experiment...

  17. Interactions Between Suspended Kaolinite Deposition and Hyporheic Exchange Flux Under Losing and Gaining Flow Conditions

    Science.gov (United States)

    Fox, Aryeh; Packman, Aaron I.; Boano, Fulvio; Phillips, Colin B.; Arnon, Shai

    2018-05-01

    Fine particle deposition and streambed clogging affect many ecological and biogeochemical processes, but little is known about the effects of groundwater flow into and out of rivers on clogging. We evaluated the effects of losing and gaining flow on the deposition of suspended kaolinite clay particles in a sand streambed and the resulting changes in rates and patterns of hyporheic exchange flux (HEF). Observations of clay deposition from the water column, clay accumulation in the streambed sediments, and water exchange with the bed demonstrated that clay deposition in the bed substantially reduced both HEF and the size of the hyporheic zone. Clay deposition and HEF were strongly coupled, leading to rapid clogging in areas of water and clay influx into the bed. Local clogging diverted exchanged water laterally, producing clay deposit layers that reduced vertical hyporheic flow and favored horizontal flow. Under gaining conditions, HEF was spatially constrained by upwelling water, which focused clay deposition in a small region on the upstream side of each bed form. Because the area of inflow into the bed was smallest under gaining conditions, local clogging required less clay mass under gaining conditions than neutral or losing conditions. These results indicate that losing and gaining flow conditions need to be considered in assessments of hyporheic exchange, fine particle dynamics in streams, and streambed clogging and restoration.

  18. The Chinese experience of rapid modernization: sociocultural changes, psychological consequences?

    Directory of Open Access Journals (Sweden)

    Jiahong eSun

    2016-04-01

    Full Text Available Mainland China has undergone profound changes dating back to the nineteenth century, including a contemporary period of rapid modernization that began in the 1980s. The result has been dramatic social, cultural, and economic shifts impacting the daily lives of Chinese people. In this paper, we explore the psychological implications of sociocultural transformation in China, emphasizing two central themes. First, rising individualism: findings from social and developmental psychology suggest that China’s rapid development has been accompanied by ever-increasing adherence to individualistic values. Second, rising rates of depression: findings from psychiatric epidemiology point to increasing prevalence of depression over this same time period, particularly in rural settings. We argue that links between sociocultural and psychological shifts in China can be usefully studied through a cultural psychology lens, emphasizing the mutual constitution of culture, mind, and brain. In particular, we note that the link between social change, individualism, and rising mental illness deserves careful attention. Our review suggests that shifting values and socialization practices shape emotion norms of concealment and display, with implications for depressive symptom presentation. The challenge comes with interpretation. Increasing prevalence rates of depression may indeed be a general response to the rapidity of sociocultural change, or a specific consequence of rising individualism—but may also result from increasingly ‘Western’ patterns of symptom presentation, or improvements in diagnostic practice. We conclude by considering the challenges posed to standard universal models of psychological phenomena.

  19. The Chinese Experience of Rapid Modernization: Sociocultural Changes, Psychological Consequences?

    Science.gov (United States)

    Sun, Jiahong; Ryder, Andrew G.

    2016-01-01

    Mainland China has undergone profound changes dating back to the nineteenth century, including a contemporary period of rapid modernization that began in the 1980s. The result has been dramatic social, cultural, and economic shifts impacting the daily lives of Chinese people. In this paper, we explore the psychological implications of sociocultural transformation in China, emphasizing two central themes. First, rising individualism: findings from social and developmental psychology suggest that China’s rapid development has been accompanied by ever-increasing adherence to individualistic values. Second, rising rates of depression: findings from psychiatric epidemiology point to increasing prevalence of depression over this same time period, particularly in rural settings. We argue that links between sociocultural and psychological shifts in China can be usefully studied through a cultural psychology lens, emphasizing the mutual constitution of culture, mind, and brain. In particular, we note that the link between social change, individualism, and rising mental illness deserves careful attention. Our review suggests that shifting values and socialization practices shape emotion norms of concealment and display, with implications for depressive symptom presentation. The challenge comes with interpretation. Increasing prevalence rates of depression may indeed be a general response to the rapidity of sociocultural change, or a specific consequence of rising individualism—but may also result from increasingly ‘Western’ patterns of symptom presentation, or improvements in diagnostic practice. We conclude by considering the challenges posed to standard universal models of psychological phenomena. PMID:27092093

  20. Study of the MWPC gas gain behaviour as a function of the gas pressure and temperature

    CERN Document Server

    Pinci, D

    2005-01-01

    The Muon System of the LHCb experiment is composed of five detection stations (M1-M5) equipped with 1368 Multi-Wire Proportional Chambers (MWPC) and 24 Triple-GEM detectors. The Multi Wire Proportional Chamber (MWPC) performances (detection efficiency, time resolution, pad-cluster size and ageing properties) are heavily dependent on the gas gain. The chamber gain depends on the gas density and therefore on the gas temperature and pressure. The impact of the environmental parameters on the MWPC gain has been studied in detail. The results, togheter with a simple method proposed to account for the gain variations, are reported in this note. The absolute gas gain at the testing voltage of 2750 V was also measured to be (1.2 +- 0.1)*10^5.

  1. Photomultipliers gain monitoring at the one percent level with a blue light pulser

    International Nuclear Information System (INIS)

    Berger, J.; Bermond, M.; Besson, P.; Favier, J.; Pessard, H.; Poulet, M.

    1988-07-01

    We describe a method and an experimental layout allowing the monitoring of photomultipliers gain. We use artificial blue light (Spark-gap with filter: 436 ± 20 nm) and three reference detectors. Short term and long term measurements are presented. The results indicate a precision better than 0.5% for the short term and 1.4% for the long term determinations. This gain monitoring system has been developed for a new neutrino oscillation reactor experiment (600 photomultipliers) starting at the Bugey nuclear plant

  2. When size matters: attention affects performance by contrast or response gain.

    Science.gov (United States)

    Herrmann, Katrin; Montaser-Kouhsari, Leila; Carrasco, Marisa; Heeger, David J

    2010-12-01

    Covert attention, the selective processing of visual information in the absence of eye movements, improves behavioral performance. We found that attention, both exogenous (involuntary) and endogenous (voluntary), can affect performance by contrast or response gain changes, depending on the stimulus size and the relative size of the attention field. These two variables were manipulated in a cueing task while stimulus contrast was varied. We observed a change in behavioral performance consonant with a change in contrast gain for small stimuli paired with spatial uncertainty and a change in response gain for large stimuli presented at one location (no uncertainty) and surrounded by irrelevant flanking distracters. A complementary neuroimaging experiment revealed that observers' attention fields were wider with than without spatial uncertainty. Our results support important predictions of the normalization model of attention and reconcile previous, seemingly contradictory findings on the effects of visual attention.

  3. Leading Gainful Employment Metric Reporting

    Science.gov (United States)

    Powers, Kristina; MacPherson, Derek

    2016-01-01

    This chapter will address the importance of intercampus involvement in reporting of gainful employment student-level data that will be used in the calculation of gainful employment metrics by the U.S. Department of Education. The authors will discuss why building relationships within the institution is critical for effective gainful employment…

  4. Polyploidy can drive rapid adaptation in yeast

    Science.gov (United States)

    Selmecki, Anna M.; Maruvka, Yosef E.; Richmond, Phillip A.; Guillet, Marie; Shoresh, Noam; Sorenson, Amber L.; de, Subhajyoti; Kishony, Roy; Michor, Franziska; Dowell, Robin; Pellman, David

    2015-03-01

    Polyploidy is observed across the tree of life, yet its influence on evolution remains incompletely understood. Polyploidy, usually whole-genome duplication, is proposed to alter the rate of evolutionary adaptation. This could occur through complex effects on the frequency or fitness of beneficial mutations. For example, in diverse cell types and organisms, immediately after a whole-genome duplication, newly formed polyploids missegregate chromosomes and undergo genetic instability. The instability following whole-genome duplications is thought to provide adaptive mutations in microorganisms and can promote tumorigenesis in mammalian cells. Polyploidy may also affect adaptation independently of beneficial mutations through ploidy-specific changes in cell physiology. Here we perform in vitro evolution experiments to test directly whether polyploidy can accelerate evolutionary adaptation. Compared with haploids and diploids, tetraploids undergo significantly faster adaptation. Mathematical modelling suggests that rapid adaptation of tetraploids is driven by higher rates of beneficial mutations with stronger fitness effects, which is supported by whole-genome sequencing and phenotypic analyses of evolved clones. Chromosome aneuploidy, concerted chromosome loss, and point mutations all provide large fitness gains. We identify several mutations whose beneficial effects are manifest specifically in the tetraploid strains. Together, these results provide direct quantitative evidence that in some environments polyploidy can accelerate evolutionary adaptation.

  5. Abnormal Auditory Gain in Hyperacusis: Investigation with a Computational Model

    Directory of Open Access Journals (Sweden)

    Peter U. Diehl

    2015-07-01

    Full Text Available Hyperacusis is a frequent auditory disorder that is characterized by abnormal loudness perception where sounds of relatively normal volume are perceived as too loud or even painfully loud. As Hyperacusis patients show decreased loudness discomfort levels (LDLs and steeper loudness growth functions, it has been hypothesized that hyperacusis might be caused by an increase in neuronal response gain in the auditory system. Moreover, since about 85% of hyperacusis patients also experience tinnitus, the conditions might be caused by a common mechanism. However, the mechanisms that give rise to hyperacusis have remained unclear.Here we have used a computational model of the auditory system to investigate candidate mechanisms for hyperacusis. Assuming that perceived loudness is proportional to the summed activity of all auditory nerve fibers, the model was tuned to reproduce normal loudness perception. We then evaluated a variety of potential hyperacusis gain mechanisms by determining their effects on model equal-loudness contours and comparing the results to the LDLs of hyperacusis patients with normal hearing thresholds. Hyperacusis was best accounted for by an increase in nonlinear gain in the central auditory system. Good fits to the average patient LDLs were obtained for a general increase in gain that affected all frequency channels to the same degree, and also for a frequency-specific gain increase in the high-frequency range. Moreover, the gain needed to be applied after subtraction of spontaneous activity of the auditory nerve, which is in contrast to current theories of tinnitus generation based on amplification of spontaneous activity. Hyperacusis and tinnitus might therefore be caused by different changes in neuronal processing in the central auditory system.

  6. Can Beta Blockers Cause Weight Gain?

    Science.gov (United States)

    ... cause weight gain? Can beta blockers cause weight gain? Answers from Sheldon G. Sheps, M.D. Yes. Weight gain can occur as a side effect of some ... and metoprolol (Lopressor, Toprol-XL). The average weight gain is about 2.6 pounds (about 1.2 ...

  7. The Benefits of Multi-Year Research Experiences: Differences in Novice and Experienced Students’ Reported Gains from Undergraduate Research

    Science.gov (United States)

    Thiry, Heather; Weston, Timothy J.; Laursen, Sandra L.; Hunter, Anne-Barrie

    2012-01-01

    This mixed-methods study explores differences in novice and experienced undergraduate students’ perceptions of their cognitive, personal, and professional gains from engaging in scientific research. The study was conducted in four different undergraduate research (UR) programs at two research-extensive universities; three of these programs had a focus on the biosciences. Seventy-three entry-level and experienced student researchers participated in in-depth, semi-structured interviews and completed the quantitative Undergraduate Research Student Self-Assessment (URSSA) instrument. Interviews and surveys assessed students’ developmental outcomes from engaging in UR. Experienced students reported distinct personal, professional, and cognitive outcomes relative to their novice peers, including a more sophisticated understanding of the process of scientific research. Students also described the trajectories by which they developed not only the intellectual skills necessary to advance in science, but also the behaviors and temperament necessary to be a scientist. The findings suggest that students benefit from multi-year UR experiences. Implications for UR program design, advising practices, and funding structures are discussed. PMID:22949423

  8. Estimating the potential gains from mergers

    DEFF Research Database (Denmark)

    Bogetoft, Peter; Wang, Dexiang

    2005-01-01

    We introduce simple production economic models to estimate the potential gains from mergers. We decompose the gains into technical ef¿ciency, size (scale) and harmony (mix) gains, and we discuss alternative ways to capture these gains. We propose to approximate the production processes using...... the non-parametric. Data Envelopment Analysis (DEA) approach, and we use the resulting operational approach to estimate the potential gains from merging agricultural extension of¿ces in Denmark....

  9. Light ion beam approach to ICF ignition, gain, and energy production

    International Nuclear Information System (INIS)

    Olson, R.; Allshouse, G.; Cook, D.

    1993-01-01

    The US Department of Energy is supporting research oriented toward both near-term defense applications as well as long-term energy applications of inertial confinement fusion (ICF). The ICF programs at Sandia National Laboratories (SNL) is directed toward validating light ions as an efficient driver for these applications. The light ion laboratory microfusion facility (LMF) is envisioned as a facility in which high gain ICF targets could be developed and utilized in defense-related experiments. The LIBRA light ion beam commercial reactor study provides a baseline approach towards the use of the high gain light ion ICF technology as a source of commercial electrical energy

  10. Light ion beam approach to ICF ignition, gain, and energy production

    International Nuclear Information System (INIS)

    Olson, R.; Allshouse, G.; Cook, D.

    1994-01-01

    The U.S. Department of Energy is supporting research oriented toward both near-term defense applications as well as long-term energy applications of inertial confinement fusion (ICF). The ICF program at Sandia National Laboratories (SNL) is directed toward validating light ions as an efficient driver for these applications. The light ion laboratory microfusion facility (LMF) is envisioned as a facility in which high gain ICF targets could be developed and utilized in defense-related experiments. The LIBRA light ion beam commercial reactor study provides a baseline approach towards the use of the high gain light ion ICF technology as a source of commercial electrical energy. (author)

  11. Gaining perspective on own illness - the lived experiences of a patient education programme for women with treated coeliac disease.

    Science.gov (United States)

    Ring Jacobsson, Lisa; Milberg, Anna; Hjelm, Katarina; Friedrichsen, Maria

    2016-05-01

    To explore the lived experiences of women with coeliac disease after attending a patient education programme, to gain a broader perspective of its influence. Adults, particularly women, with coeliac disease report suffering from poor well-being and reduced quality of life in terms of health. Patient education programmes might support and encourage them in the search for possible improvements in lifestyle and in their approach to the disease. A qualitative phenomenological study. Personal narrative interviews with 14 women suffering from coeliac disease who had participated in an educational programme. Data analysis in accordance with Giorgi was performed. The essential structure of women's lived experiences following their participation in the patient education programme was found to be an interaction with others with the same disease, which left the women feeling individually strengthened. The interaction enabled the participants to acquire a broader view of their life with coeliac disease. As a result, this realigned their sense of self in relation to their own disease. In coping with coeliac disease, it seems that women need interaction with others with the disease to experience togetherness within a group, get the opportunity to compare themselves with others and to exchange knowledge. The interaction appears to result in that women acquire an overview of life with the disease, develop a greater confidence and dare to try new things in life. When designing a patient education programme it seems important to consider the needs of persons to meet others with the same disease, and to ask them about their need for knowledge, rather than simply assuming that health care professionals know what they need. © 2016 John Wiley & Sons Ltd.

  12. Prediction of direct and indirect genetic gains and genotypic correlations in rubber tree progenies

    Directory of Open Access Journals (Sweden)

    Cecília Khusala Verardi

    2011-09-01

    Full Text Available The objective of this work was to estimate the genetic parameters, genotypic and phenotypic correlations, and direct and indirect genetic gains among and within rubber tree (Hevea brasiliensis progenies. The experiment was set up at the Municipality of Jaú, SP, Brazil. A randomized complete block design was used, with 22 treatments (progenies, 6 replicates, and 10 plants per plot at a spacing of 3x3 m. Three‑year‑old progenies were assessed for girth, rubber yield, and bark thickness by direct and indirect gains and genotypic correlations. The number of latex vessel rings showed the best correlations, correlating positively and significantly with girth and bark thickness. Selection gains among progenies were greater than within progeny for all the variables analyzed. Total gains obtained were high, especially for girth increase and rubber yield, which were 93.38 and 105.95%, respectively. Young progeny selection can maximize the expected genetic gains, reducing the rubber tree selection cycle.

  13. Obesity, weight gain, and ovarian cancer risk in African American women.

    Science.gov (United States)

    Bandera, Elisa V; Qin, Bo; Moorman, Patricia G; Alberg, Anthony J; Barnholtz-Sloan, Jill S; Bondy, Melissa; Cote, Michele L; Funkhouser, Ellen; Peters, Edward S; Schwartz, Ann G; Terry, Paul; Schildkraut, Joellen M

    2016-08-01

    Although there is growing evidence that higher adiposity increases ovarian cancer risk, little is known about its impact in African American (AA) women, the racial/ethnic group with the highest prevalence of obesity. We evaluated the impact of body mass index (BMI) 1 year before diagnosis and weight gain since age 18 years on ovarian cancer risk in a population-based case-control study in AA women in 11 geographical areas in the US. Cases (n = 492) and age and site matched controls (n = 696) were identified through rapid case ascertainment and random-digit-dialing, respectively. Information was collected on demographic and lifestyle factors, including self-reported height, weight at age 18 and weight 1 year before diagnosis/interview. Multivariable logistic regression was used to compute odds ratios (OR) and 95% confidence intervals (CI), adjusting for potential covariates. Obese women had elevated ovarian cancer risk, particularly for BMI ≥ 40 kg/m(2) compared to BMI Obesity and excessive adult weight gain may increase ovarian cancer risk in post-menopausal AA women. © 2016 UICC.

  14. Experimental characteristics of a high-gain free-electron laser amplifier operating at 8-mm and 2-mm wavelengths

    International Nuclear Information System (INIS)

    Throop, A.L.; Orzechowski, T.J.; Anderson, B.R.

    1987-01-01

    The Electron Laser Facility (ELF) at the Lawrence Livermore National Laboratory (LLNL) uses a high-current induction linac (3.5 MeV, 1000 A), in conjunction with a pulsed electromagnetic wiggler (4.0 M, 4000 G), to operate a free electron laser (FEL) that produces intense radiation in the microwave regime (2 to 8 mm). ELF is a high-gain, single-pass amplifier, using a commercial microwave source as an oscillator input (200 W-50 kW). Previous experiments at 35 GHz produced exponential gains of 40 dB/m, peak powers exceeding 1 GW, and beam-to-rf conversion efficiencies of 34%. Recent experiments at 140 GHz have demonstrated exponential gains of 22 dB/m, peak powers exceeding 50 MW, and total gains of 65 dB. In this paper, we describe the experimental results at these two frequencies and compare then with the predictions of simulation codes

  15. Rapid Statistical Learning Supporting Word Extraction From Continuous Speech.

    Science.gov (United States)

    Batterink, Laura J

    2017-07-01

    The identification of words in continuous speech, known as speech segmentation, is a critical early step in language acquisition. This process is partially supported by statistical learning, the ability to extract patterns from the environment. Given that speech segmentation represents a potential bottleneck for language acquisition, patterns in speech may be extracted very rapidly, without extensive exposure. This hypothesis was examined by exposing participants to continuous speech streams composed of novel repeating nonsense words. Learning was measured on-line using a reaction time task. After merely one exposure to an embedded novel word, learners demonstrated significant learning effects, as revealed by faster responses to predictable than to unpredictable syllables. These results demonstrate that learners gained sensitivity to the statistical structure of unfamiliar speech on a very rapid timescale. This ability may play an essential role in early stages of language acquisition, allowing learners to rapidly identify word candidates and "break in" to an unfamiliar language.

  16. Assigning probability gain for precursors of four large Chinese earthquakes

    Energy Technology Data Exchange (ETDEWEB)

    Cao, T.; Aki, K.

    1983-03-10

    We extend the concept of probability gain associated with a precursor (Aki, 1981) to a set of precursors which may be mutually dependent. Making use of a new formula, we derive a criterion for selecting precursors from a given data set in order to calculate the probability gain. The probabilities per unit time immediately before four large Chinese earthquakes are calculated. They are approximately 0.09, 0.09, 0.07 and 0.08 per day for 1975 Haicheng (M = 7.3), 1976 Tangshan (M = 7.8), 1976 Longling (M = 7.6), and Songpan (M = 7.2) earthquakes, respectively. These results are encouraging because they suggest that the investigated precursory phenomena may have included the complete information for earthquake prediction, at least for the above earthquakes. With this method, the step-by-step approach to prediction used in China may be quantified in terms of the probability of earthquake occurrence. The ln P versus t curve (where P is the probability of earthquake occurrence at time t) shows that ln P does not increase with t linearly but more rapidly as the time of earthquake approaches.

  17. Rapid prototyping model for percutaneous nephrolithotomy training.

    Science.gov (United States)

    Bruyère, Franck; Leroux, Cecile; Brunereau, Laurent; Lermusiaux, Patrick

    2008-01-01

    Rapid prototyping is a technique used for creating computer images in three dimensions more efficiently than classic techniques. Percutaneous nephrolithotomy (PCNL) is a popular method to remove kidney stones; however, broader use by the urologic community has been hampered by the morbidity associated with needle puncture to gain access to the renal calix (bleeding, pneumothorax, hydrothorax, inadvertent colon injury). A training model to improve technique and understanding of renal anatomy could improve complications related to renal puncture; however, no model currently exists for resident training. We created a training model using the rapid prototyping technique based on abdominal CT images of a patient scheduled to undergo PCNL. This allowed our staff and residents to train on the model before performing the operation. This model allowed anticipation of particular difficulties inherent to the patient's anatomy. After training, the procedure proceeded without complication, and the patient was discharged at postoperative day 1 without problems. We hypothesize that rapid prototyping could be useful for resident education, allowing the creation of numerous models for research and surgical training. In addition, we anticipate that experienced urologists could find this technique helpful in preparation for difficult PCNL operations.

  18. Application of gain scheduling to the control of batch bioreactors

    Science.gov (United States)

    Cardello, Ralph; San, Ka-Yiu

    1987-01-01

    The implementation of control algorithms to batch bioreactors is often complicated by the inherent variations in process dynamics during the course of fermentation. Such a wide operating range may render the performance of fixed gain PID controllers unsatisfactory. In this work, a detailed study on the control of batch fermentation is performed. Furthermore, a simple batch controller design is proposed which incorporates the concept of gain-scheduling, a subclass of adaptive control, with oxygen uptake rate as an auxiliary variable. The control of oxygen tension in the biorector is used as a vehicle to convey the proposed idea, analysis and results. Simulation experiments indicate significant improvement in controller performance can be achieved by the proposed approach even in the presence of measurement noise.

  19. Using Multilayered Substrate Integrated Waveguide to Design Microwave Gain Equalizer

    Directory of Open Access Journals (Sweden)

    Yongfei Wang

    2014-01-01

    Full Text Available This paper presents the design and experiment of a novel microwave gain equalizer based on the substrate integrated waveguide (SIW technique. The proposed equalizer is formed by an SIW loaded by SIW resonators, which has very compact structure and can compensate for gain slope of microwave systems. Equivalent circuit analysis is given about the proposed structure for a better insight into the structure’s response. A Ku-Band equalizer with four SIW resonators is simulated and fabricated with a multilayer printed circuit board process. The measured results show good performance and agreement with the simulated results; an attenuation slope of −4.5 dB over 12.5–13.5 GHz is reached with a size reduction of 76%.

  20. Sequence specific motor performance gains after memory consolidation in children and adolescents.

    Directory of Open Access Journals (Sweden)

    Shoshi Dorfberger

    Full Text Available Memory consolidation for a trained sequence of finger opposition movements, in 9- and 12-year-old children, was recently found to be significantly less susceptible to interference by a subsequent training experience, compared to that of 17-year-olds. It was suggested that, in children, the experience of training on any sequence of finger movements may affect the performance of the sequence elements, component movements, rather than the sequence as a unit; the latter has been implicated in the learning of the task by adults. This hypothesis implied a possible childhood advantage in the ability to transfer the gains from a trained to the reversed, untrained, sequence of movements. Here we report the results of transfer tests undertaken to test this proposal in 9-, 12-, and 17-year-olds after training in the finger-to-thumb opposition sequence (FOS learning task. Our results show that the performance gains in the trained sequence partially transferred from the left, trained hand, to the untrained hand at 48-hours after a single training session in the three age-groups tested. However, there was very little transfer of the gains from the trained to the untrained, reversed, sequence performed by either hand. The results indicate sequence specific post-training gains in FOS performance, as opposed to a general improvement in performance of the individual, component, movements that comprised both the trained and untrained sequences. These results do not support the proposal that the reduced susceptibility to interference, in children before adolescence, reflects a difference in movement syntax representation after training.

  1. Sequence specific motor performance gains after memory consolidation in children and adolescents.

    Science.gov (United States)

    Dorfberger, Shoshi; Adi-Japha, Esther; Karni, Avi

    2012-01-01

    Memory consolidation for a trained sequence of finger opposition movements, in 9- and 12-year-old children, was recently found to be significantly less susceptible to interference by a subsequent training experience, compared to that of 17-year-olds. It was suggested that, in children, the experience of training on any sequence of finger movements may affect the performance of the sequence elements, component movements, rather than the sequence as a unit; the latter has been implicated in the learning of the task by adults. This hypothesis implied a possible childhood advantage in the ability to transfer the gains from a trained to the reversed, untrained, sequence of movements. Here we report the results of transfer tests undertaken to test this proposal in 9-, 12-, and 17-year-olds after training in the finger-to-thumb opposition sequence (FOS) learning task. Our results show that the performance gains in the trained sequence partially transferred from the left, trained hand, to the untrained hand at 48-hours after a single training session in the three age-groups tested. However, there was very little transfer of the gains from the trained to the untrained, reversed, sequence performed by either hand. The results indicate sequence specific post-training gains in FOS performance, as opposed to a general improvement in performance of the individual, component, movements that comprised both the trained and untrained sequences. These results do not support the proposal that the reduced susceptibility to interference, in children before adolescence, reflects a difference in movement syntax representation after training.

  2. Study of gain variation as a function of physical parameters of GEM foil

    CERN Document Server

    Das, Supriya

    2015-01-01

    The ALICE experiment at LHC has planned to upgrade the TPC by replacing the MWPC with GEM based detecting elements to restrict the IBF to a tolerable value. However the variation of the gain as a function of physical parameters of industrially produced large size GEM foils is needed to be studied as a part of the QA procedure for the detector. The size of the electron avalanche and consequently the gain for GEM based detectors depend on the electric field distribution inside the holes. Geometry of a hole plays an important role in defining the electric field inside it. In this work we have studied the variation of the gain as a function of the hole diameters using Garfield++ simulation package.

  3. Gain variation of phototube in the frequency domain at very short term

    Energy Technology Data Exchange (ETDEWEB)

    Celani, F; Codino, A; Cora, U; Falcioni, R; Felici, G; Levy, G [Istituto Nazionale di Fisica Nucleare, Frascati (Italy); D' Ettorre Piazzoli, B; Mannocchi, G [Consiglio Nazionale delle Ricerche, Turin (Italy). Lab. di Cosmo-Geofisica; Bologna, G; Picchi, P [Turin Univ. (Italy). Ist. di Fisica

    1981-11-15

    A new very fast pulse generator with injected charge control is used to drive a LED-phototube configuration, reproducing the working conditions of many experiments in high energy physics which make use of fast plastic scintillators. We have studied the behavior of the Phillips XP 2008 phototube operated under such experimental conditions. We find a gain shift vs. frequency that is a function of intensity of the light incident on the PM. For an output ranging between 83 and 450 pC the gain shift at about 33 kHz varies in the range 15-33%.

  4. Rapid Software Development for Experiment Control at OPAL

    International Nuclear Information System (INIS)

    Hathaway, P.V.; Lam, Tony; Franceschini, Ferdi; Hauser, Nick; Rayner, Hugh

    2005-01-01

    Full text: ANSTO is undertaking the parallel development of instrument control and graphical experiment interface software for seven neutron beam instruments at OPAL. Each instrument poses several challenges for a common system solution, including custom detector interfaces, a range of motion and beamline optics schema, and a spectrum of online data reduction requirements. To provide a superior system with the least development effort, the computing team have adopted proven, configurable, server-based control software (SICS)1., a highly Integrated Scientific Experimental Environment (GumTree)2. and industry-standard database management systems. The resulting graphical interfaces allow operation in a familiar experiment domain, with monitoring of data and parameters independent of control system specifics. GumTree presents the experimenter with a consistent interface for experiment management, instrument control and data reduction tasks. The facility instrument scientists can easily reconfigure instruments and add ancillaries. The user community can expect a reduced learning curve for performing each experiment. GumTree can be installed anywhere for pre-experiment familiarisation, postprocessing of acquired data sets, and integration with third party analysis tools. Instrument scientists are seeing faster software development iterations and have a solid basis to prepare for the next suite of instruments. 1. SICS from PSI (lns00.psi.ch). 2. GumTree (gumtree.sourceforge.net), new site: http://gumtree.sourceforge.net/wiki/index.php/Main_Page

  5. Advanced Communication Technology Satellite (ACTS) multibeam antenna technology verification experiments

    Science.gov (United States)

    Acosta, Roberto J.; Larko, Jeffrey M.; Lagin, Alan R.

    1992-01-01

    The Advanced Communication Technology Satellite (ACTS) is a key to reaching NASA's goal of developing high-risk, advanced communications technology using multiple frequency bands to support the nation's future communication needs. Using the multiple, dynamic hopping spot beams, and advanced on board switching and processing systems, ACTS will open a new era in communications satellite technology. One of the key technologies to be validated as part of the ACTS program is the multibeam antenna with rapidly reconfigurable hopping and fixed spot beam to serve users equipped with small-aperature terminals within the coverage areas. The proposed antenna technology experiments are designed to evaluate in-orbit ACTS multibeam antenna performance (radiation pattern, gain, cross pol levels, etc.).

  6. A gain-coefficient switched Alexandrite laser

    International Nuclear Information System (INIS)

    Lee, Chris J; Van der Slot, Peter J M; Boller, Klaus-J

    2013-01-01

    We report on a gain-coefficient switched Alexandrite laser. An electro-optic modulator is used to switch between high and low gain states by making use of the polarization dependent gain of Alexandrite. In gain-coefficient switched mode, the laser produces 85 ns pulses with a pulse energy of 240 mJ at a repetition rate of 5 Hz.

  7. Enhancing genetic gain in the era of molecular breeding.

    Science.gov (United States)

    Xu, Yunbi; Li, Ping; Zou, Cheng; Lu, Yanli; Xie, Chuanxiao; Zhang, Xuecai; Prasanna, Boddupalli M; Olsen, Michael S

    2017-05-17

    As one of the important concepts in conventional quantitative genetics and breeding, genetic gain can be defined as the amount of increase in performance that is achieved annually through artificial selection. To develop pro ducts that meet the increasing demand of mankind, especially for food and feed, in addition to various industrial uses, breeders are challenged to enhance the potential of genetic gain continuously, at ever higher rates, while they close the gaps that remain between the yield potential in breeders' demonstration trials and the actual yield in farmers' fields. Factors affecting genetic gain include genetic variation available in breeding materials, heritability for traits of interest, selection intensity, and the time required to complete a breeding cycle. Genetic gain can be improved through enhancing the potential and closing the gaps, which has been evolving and complemented with modern breeding techniques and platforms, mainly driven by molecular and genomic tools, combined with improved agronomic practice. Several key strategies are reviewed in this article. Favorable genetic variation can be unlocked and created through molecular and genomic approaches including mutation, gene mapping and discovery, and transgene and genome editing. Estimation of heritability can be improved by refining field experiments through well-controlled and precisely assayed environmental factors or envirotyping, particularly for understanding and controlling spatial heterogeneity at the field level. Selection intensity can be significantly heightened through improvements in the scale and precision of genotyping and phenotyping. The breeding cycle time can be shortened by accelerating breeding procedures through integrated breeding approaches such as marker-assisted selection and doubled haploid development. All the strategies can be integrated with other widely used conventional approaches in breeding programs to enhance genetic gain. More transdisciplinary

  8. Study of gain-coupled distributed feedback laser based on high order surface gain-coupled gratings

    Science.gov (United States)

    Gao, Feng; Qin, Li; Chen, Yongyi; Jia, Peng; Chen, Chao; Cheng, LiWen; Chen, Hong; Liang, Lei; Zeng, Yugang; Zhang, Xing; Wu, Hao; Ning, Yongqiang; Wang, Lijun

    2018-03-01

    Single-longitudinal-mode, gain-coupled distributed feedback (DFB) lasers based on high order surface gain-coupled gratings are achieved. Periodic surface metal p-contacts with insulated grooves realize gain-coupled mechanism. To enhance gain contrast in the quantum wells without the introduction of effective index-coupled effect, groove length and depth were well designed. Our devices provided a single longitudinal mode with the maximum CW output power up to 48.8 mW/facet at 971.31 nm at 250 mA without facet coating, 3dB linewidth (39 dB). Optical bistable characteristic was observed with a threshold current difference. Experimentally, devices with different cavity lengths were contrasted on power-current and spectrum characteristics. Due to easy fabrication technique and stable performance, it provides a method of fabricating practical gain-coupled distributed feedback lasers for commercial applications.

  9. Rapid, autonomous analysis of He spectra I: Overview of the RadID program, user experience, and structure

    Energy Technology Data Exchange (ETDEWEB)

    Gosnell, Thomas B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Chavez, Joseph R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rowland, Mark S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wong, James L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2014-02-26

    RadID is a new gamma-ray spectrum analysis program for rapid screening of HPGe gamma-ray data to reveal the presence of radionuclide signatures. It is an autonomous, rule-based heuristic system that can identify well over 200 radioactive sources with particular interest in uranium and plutonium characteristics. It executes in about one second. RadID does not require knowledge of the detector efficiency, the source-to-detector distance, or the geometry of the inspected radiation source—including any shielding. In this first of a three-document series we sketch the RadID program’s origin, its minimal requirements, the user experience, and the program operation.

  10. Comparing the cost-per-QALYs gained and cost-per-DALYs averted literatures.

    Science.gov (United States)

    Neumann, Peter J; Anderson, Jordan E; Panzer, Ari D; Pope, Elle F; D'Cruz, Brittany N; Kim, David D; Cohen, Joshua T

    2018-01-18

    Background : We examined the similarities and differences between studies using two common metrics used in cost-effectiveness analyses (CEAs): cost per quality-adjusted life years (QALYs) gained and cost per disability-adjusted life year (DALY) averted. Methods : We used the Tufts Medical Center CEA Registry, which contains English-language cost-per-QALY gained studies, and  Global Cost-Effectiveness Analysis (GHCEA) Registry, which contains cost-per-DALY averted studies. We examined study characteristics including intervention type, sponsor, country, and primary disease, and also analysed the number of CEAs versus disease burden estimates for major diseases and conditions across three geographic regions. Results : We identified 6,438 cost-per-QALY and 543 cost-per-DALY studies published through 2016 and observed rapid growth in publication rates for both literatures. Cost-per-QALY studies were most likely to examine pharmaceuticals and interventions in high-income countries. Cost-per-DALY studies predominantly focused on infectious disease interventions and interventions in low and lower-middle income countries. We found discrepancies in the number of published CEAs for certain diseases and conditions in certain regions, suggesting "under-studied" areas (e.g., cardiovascular disease in Southeast Asia, East Asia, and Oceania and "overstudied" areas (e.g., HIV in Sub Saharan Africa) relative to disease burden in those regions. Conclusions : The number of cost-per QALY and cost-per-DALY analyses has grown rapidly with applications to diverse interventions and diseases.  Discrepancies between the number of published studies and disease burden suggest funding opportunities for future cost-effectiveness research.

  11. Brief Parenteral Nutrition Accelerates Weight Gain, Head Growth Even in Healthy VLBWs

    Science.gov (United States)

    Morisaki, Naho; Belfort, Mandy B.; McCormick, Marie C.; Mori, Rintaro; Noma, Hisashi; Kusuda, Satoshi; Fujimura, Masanori

    2014-01-01

    Introduction Whether parenteral nutrition benefits growth of very low birth weight (VLBW) preterm infants in the setting of rapid enteral feeding advancement is unclear. Our aim was to examine this issue using data from Japan, where enteral feeding typically advances at a rapid rate. Methods We studied 4005 hospitalized VLBW, very preterm (23–32 weeks' gestation) infants who reached full enteral feeding (100 ml/kg/day) by day 14, from 75 institutions in the Neonatal Research Network Japan (2003–2007). Main outcomes were weight gain, head growth, and extra-uterine growth restriction (EUGR, measurement parenteral nutrition. Adjusting for maternal, infant, and institutional characteristics, infants who received parenteral nutrition had greater weight gain [0.09 standard deviation (SD), 95% CI: 0.02, 0.16] and head growth (0.16 SD, 95% CI: 0.05, 0.28); lower odds of EUGR by head circumference (OR 0.66, 95% CI: 0.49, 0.88). No statistically significant difference was seen in the proportion of infants with EUGR at discharge. SGA infants and infants who took more than a week until full feeding had larger estimates. Discussion Even in infants who are able to establish enteral nutrition within 2 weeks, deprivation of parenteral nutrition in the first weeks of life could lead to under nutrition, but infants who reached full feeding within one week benefit least. It is important to predict which infants are likely or not likely to advance on enteral feedings within a week and balance enteral and parenteral nutrition for these infants. PMID:24586323

  12. Rapid structural analysis of nanomaterials in aqueous solutions

    Science.gov (United States)

    Ryuzaki, Sou; Tsutsui, Makusu; He, Yuhui; Yokota, Kazumichi; Arima, Akihide; Morikawa, Takanori; Taniguchi, Masateru; Kawai, Tomoji

    2017-04-01

    Rapid structural analysis of nanoscale matter in a liquid environment represents innovative technologies that reveal the identities and functions of biologically important molecules. However, there is currently no method with high spatio-temporal resolution that can scan individual particles in solutions to gain structural information. Here we report the development of a nanopore platform realizing quantitative structural analysis for suspended nanomaterials in solutions with a high z-axis and xy-plane spatial resolution of 35.8 ± 1.1 and 12 nm, respectively. We used a low thickness-to-diameter aspect ratio pore architecture for achieving cross sectional areas of analyte (i.e. tomograms). Combining this with multiphysics simulation methods to translate ionic current data into tomograms, we demonstrated rapid structural analysis of single polystyrene (Pst) beads and single dumbbell-like Pst beads in aqueous solutions.

  13. Rapid response learning of brand logo priming: Evidence that brand priming is not dominated by rapid response learning.

    Science.gov (United States)

    Boehm, Stephan G; Smith, Ciaran; Muench, Niklas; Noble, Kirsty; Atherton, Catherine

    2017-08-31

    Repetition priming increases the accuracy and speed of responses to repeatedly processed stimuli. Repetition priming can result from two complementary sources: rapid response learning and facilitation within perceptual and conceptual networks. In conceptual classification tasks, rapid response learning dominates priming of object recognition, but it does not dominate priming of person recognition. This suggests that the relative engagement of network facilitation and rapid response learning depends on the stimulus domain. Here, we addressed the importance of the stimulus domain for rapid response learning by investigating priming in another domain, brands. In three experiments, participants performed conceptual decisions for brand logos. Strong priming was present, but it was not dominated by rapid response learning. These findings add further support to the importance of the stimulus domain for the relative importance of network facilitation and rapid response learning, and they indicate that brand priming is more similar to person recognition priming than object recognition priming, perhaps because priming of both brands and persons requires individuation.

  14. Anatomical knowledge gain through a clay-modeling exercise compared to live and video observations.

    Science.gov (United States)

    Kooloos, Jan G M; Schepens-Franke, Annelieke N; Bergman, Esther M; Donders, Rogier A R T; Vorstenbosch, Marc A T M

    2014-01-01

    Clay modeling is increasingly used as a teaching method other than dissection. The haptic experience during clay modeling is supposed to correspond to the learning effect of manipulations during exercises in the dissection room involving tissues and organs. We questioned this assumption in two pretest-post-test experiments. In these experiments, the learning effects of clay modeling were compared to either live observations (Experiment I) or video observations (Experiment II) of the clay-modeling exercise. The effects of learning were measured with multiple choice questions, extended matching questions, and recognition of structures on illustrations of cross-sections. Analysis of covariance with pretest scores as the covariate was used to elaborate the results. Experiment I showed a significantly higher post-test score for the observers, whereas Experiment II showed a significantly higher post-test score for the clay modelers. This study shows that (1) students who perform clay-modeling exercises show less gain in anatomical knowledge than students who attentively observe the same exercise being carried out and (2) performing a clay-modeling exercise is better in anatomical knowledge gain compared to the study of a video of the recorded exercise. The most important learning effect seems to be the engagement in the exercise, focusing attention and stimulating time on task. © 2014 American Association of Anatomists.

  15. The order of information processing alters economic gain-loss framing effects.

    Science.gov (United States)

    Kwak, Youngbin; Huettel, Scott

    2018-01-01

    Adaptive decision making requires analysis of available information during the process of choice. In many decisions that information is presented visually - which means that variations in visual properties (e.g., salience, complexity) can potentially influence the process of choice. In the current study, we demonstrate that variation in the left-right positioning of risky and safe decision options can influence the canonical gain-loss framing effect. Two experiments were conducted using an economic framing task in which participants chose between gambles and certain outcomes. The first experiment demonstrated that the magnitude of the gain-loss framing effect was greater when the certain option signaling the current frame was presented on the left side of the visual display. Eye-tracking data during task performance showed a left-gaze bias for initial fixations, suggesting that the option presented on the left side was processed first. Combination of eye-tracking and choice data revealed that there was a significant effect of direction of first gaze (i.e. left vs. right) as well as an interaction between gaze direction and identity of the first fixated information (i.e. certain vs. gamble) regardless of frame. A second experiment presented the gamble and certain options in a random order, with a temporal delay between their presentations. We found that the magnitude of gain-loss framing was larger when the certain option was presented first, regardless of left and right positioning, only in individuals with lower risk-taking tendencies. The effect of presentation order on framing was not present in high risk-takers. These results suggest that the sequence of visual information processing as well as their left-right positioning can bias choices by changing the impact of the presented information during risky decision making. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Sucrose exposure in early life alters adult motivation and weight gain.

    Directory of Open Access Journals (Sweden)

    Cristianne R M Frazier

    2008-09-01

    Full Text Available The cause of the current increase in obesity in westernized nations is poorly understood but is frequently attributed to a 'thrifty genotype,' an evolutionary predisposition to store calories in times of plenty to protect against future scarcity. In modern, industrialized environments that provide a ready, uninterrupted supply of energy-rich foods at low cost, this genetic predisposition is hypothesized to lead to obesity. Children are also exposed to this 'obesogenic' environment; however, whether such early dietary experience has developmental effects and contributes to adult vulnerability to obesity is unknown. Using mice, we tested the hypothesis that dietary experience during childhood and adolescence affects adult obesity risk. We gave mice unlimited or no access to sucrose for a short period post-weaning and measured sucrose-seeking, food consumption, and weight gain in adulthood. Unlimited access to sucrose early in life reduced sucrose-seeking when work was required to obtain it. When high-sugar/high-fat dietary options were made freely-available, however, the sucrose-exposed mice gained more weight than mice without early sucrose exposure. These results suggest that early, unlimited exposure to sucrose reduces motivation to acquire sucrose but promotes weight gain in adulthood when the cost of acquiring palatable, energy dense foods is low. This study demonstrates that early post-weaning experience can modify the expression of a 'thrifty genotype' and alter an adult animal's response to its environment, a finding consistent with evidence of pre- and peri-natal programming of adult obesity risk by maternal nutritional status. Our findings suggest the window for developmental effects of diet may extend into childhood, an observation with potentially important implications for both research and public policy in addressing the rising incidence of obesity.

  17. Sucrose exposure in early life alters adult motivation and weight gain.

    Science.gov (United States)

    Frazier, Cristianne R M; Mason, Peggy; Zhuang, Xiaoxi; Beeler, Jeff A

    2008-09-17

    The cause of the current increase in obesity in westernized nations is poorly understood but is frequently attributed to a 'thrifty genotype,' an evolutionary predisposition to store calories in times of plenty to protect against future scarcity. In modern, industrialized environments that provide a ready, uninterrupted supply of energy-rich foods at low cost, this genetic predisposition is hypothesized to lead to obesity. Children are also exposed to this 'obesogenic' environment; however, whether such early dietary experience has developmental effects and contributes to adult vulnerability to obesity is unknown. Using mice, we tested the hypothesis that dietary experience during childhood and adolescence affects adult obesity risk. We gave mice unlimited or no access to sucrose for a short period post-weaning and measured sucrose-seeking, food consumption, and weight gain in adulthood. Unlimited access to sucrose early in life reduced sucrose-seeking when work was required to obtain it. When high-sugar/high-fat dietary options were made freely-available, however, the sucrose-exposed mice gained more weight than mice without early sucrose exposure. These results suggest that early, unlimited exposure to sucrose reduces motivation to acquire sucrose but promotes weight gain in adulthood when the cost of acquiring palatable, energy dense foods is low. This study demonstrates that early post-weaning experience can modify the expression of a 'thrifty genotype' and alter an adult animal's response to its environment, a finding consistent with evidence of pre- and peri-natal programming of adult obesity risk by maternal nutritional status. Our findings suggest the window for developmental effects of diet may extend into childhood, an observation with potentially important implications for both research and public policy in addressing the rising incidence of obesity.

  18. Weight gain following treatment of hyperthyroidism.

    Science.gov (United States)

    Dale, J; Daykin, J; Holder, R; Sheppard, M C; Franklyn, J A

    2001-08-01

    Patients frequently express concern that treating hyperthyroidism will lead to excessive weight gain. This study aimed to determine the extent of, and risk factors for, weight gain in an unselected group of hyperthyroid patients. We investigated 162 consecutive hyperthyroid patients followed for at least 6 months. Height, weight, clinical features, biochemistry and management were recorded at each clinic visit. Documented weight gain was 5.42 +/- 0.46 kg (mean +/- SE) and increase in BMI was 8.49 +/- 0.71%, over a mean 24.2 +/- 1.6 months. Pre-existing obesity, Graves' disease causing hyperthyroidism, weight loss before presentation and length of follow-up each independently predicted weight gain. Patients treated with thionamides or radioiodine gained a similar amount of weight (thionamides, n = 87, 5.16 +/- 0.63 kg vs. radioiodine, n = 62, 4.75 +/- 0.57 kg, P = 0.645), but patients who underwent thyroidectomy (n = 13) gained more weight (10.27 +/- 2.56 kg vs. others, P = 0.007). Development of hypothyroidism (even transiently) was associated with weight gain (never hypothyroid, n = 102, 4.57 +/- 0.52 kg, transiently hypothyroid, n = 29, 5.37 +/- 0.85 kg, on T4, n = 31, 8.06 +/- 1.42 kg, P = 0.014). This difference remained after correcting for length of follow-up. In the whole cohort, weight increased by 3.95 +/- 0.40 kg at 1 year (n = 144) to 9.91 +/- 1.62 kg after 4 years (n = 27) (P = 0.008), representing a mean weight gain of 3.66 +/- 0.44 kg/year. We have demonstrated marked weight gain after treatment of hyperthyroidism. Pre-existing obesity, a diagnosis of Graves' disease and prior weight loss independently predicted weight gain and weight continued to rise with time. Patients who became hypothyroid, despite T4 replacement, gained most weight.

  19. [Experience of rapid drug desensitization therapy in the treatment of mycobacterial disease].

    Science.gov (United States)

    Sasaki, Yuka; Kurashima, Atsuyuki; Morimoto, Kozo; Okumura, Masao; Watanabe, Masato; Yoshiyama, Takashi; Ogata, Hideo; Gotoh, Hajime; Kudoh, Shoji; Suzuki, Hiroaki

    2014-11-01

    Drugs for tuberculosis and non-tuberculosis mycobacterial diseases are limited. In particular, no new drugs for non-tuberculosis mycobacterial disease have been developed in recent years. Antimycobacterial drugs have many adverse reactions, for which drug desensitization therapy has been used. Rapid drug desensitization (RDD) therapy, including antituberculosis drugs and clarithromycin, has been implemented in many regions in Europe and the United States. We investigated the validity of RDD therapy in Japan. We report our experience with RDD therapy in 13 patients who developed severe drug allergy to antimycobacterial treatment. The desensitization protocol reported by Holland and Cernandas was adapted. The underlying diseases were 7 cases of pulmonary Mycobacterium avium complex disease and 6 cases of pulmonary tuberculosis. Isoniazid was readministered in 2 (100%) of 2 patients; rifampicin, in 8 (67.7%) of 12 patients; ethambutol, in 4 (67.7%) of 6 patients; and clarithromycin, in 2 (100%) of 2 patients. In Japan, the desensitization therapy recommended by the Treatment Committee of the Japanese Society for Tuberculosis have been implemented generally. We think RDD therapy is effective and safe as the other desensitization therapy. We will continue to investigate the efficiency of RDD therapy in patients who had discontinued antimycobacterial treatment because of the drug allergic reaction.

  20. Food (In)Security in Rapidly Urbanising, Low-Income Contexts

    OpenAIRE

    Cecilia Tacoli

    2017-01-01

    Urbanisation in low and middle-income nations presents both opportunities and immense challenges. As urban centres grow rapidly, inadequate housing and the lack of basic infrastructure and services affect a large and growing proportion of their population. There is also a growing body of evidence on urban poverty and its links with environmental hazards. There is, however, limited knowledge of how these challenges affect the ways in which poor urban residents gain access to food and secure he...

  1. When gains loom larger than losses: reversed loss aversion for small amounts of money.

    Science.gov (United States)

    Harinck, Fieke; Van Dijk, Eric; Van Beest, Ilja; Mersmann, Paul

    2007-12-01

    Previous research has generally shown that people are loss averse; that is, they weigh losses more heavily than gains. In a series of three experiments, we found that for small outcomes, this pattern is reversed, and gains loom larger than losses. We explain this reversal on the basis of (a) the hedonic principle, which states that individuals are motivated to maximize pleasure and to minimize pain, and (b) the assumption that small losses are more easily discounted cognitively than large losses are.

  2. Survey of methods for rapid spin reversal

    International Nuclear Information System (INIS)

    McKibben, J.L.

    1980-01-01

    The need for rapid spin reversal technique in polarization experiments is discussed. The ground-state atomic-beam source equipped with two rf transitions for hydrogen can be reversed rapidly, and is now in use on several accelerators. It is the optimum choice provided the accelerator can accept H + ions. At present all rapid reversal experiments using H - ions are done with Lamb-shift sources; however, this is not a unique choice. Three methods for the reversal of the spin of the atomic beam within the Lamb-shift source are discussed in order of development. Coherent intensity and perhaps focus modulation seem to be the biggest problems in both types of sources. Methods for reducing these modulations in the Lamb-shift source are discussed. The same Lamb-shift apparatus is easily modified to provide information on the atomic physics of quenching of the 2S/sub 1/2/ states versus spin orientation, and this is also discussed. 2 figures

  3. Life after unsuccessful IVF treatment in an assisted reproduction unit: a qualitative analysis of gains through loss among Chinese persons in Hong Kong.

    Science.gov (United States)

    Lee, Geok Ling; Hui Choi, W H; Chan, Celia H Y; Chan, Cecilia L W; Ng, Ernest H Y

    2009-08-01

    Previous studies examining experiences of infertility focused mainly on the aspect of loss but neglected the possible gains realized through surviving the experience of infertility. The success rate of IVF remains relatively low, and we used the strengths perspective to examine adjustment after unsuccessful treatment. This study aims to provide an in-depth description of the gains perceived by Chinese men and women and how they re-constructed their lives after unsuccessful IVF treatment. Four couples and another six women who experienced unsuccessful IVF treatment were recruited from an assisted reproduction clinic. Data were collected through in-depth interviews, using a grounded theory constructivist approach. Of the 10 women and 4 men interviewed, 9 remained childless, 3 had adopted a child and 2 had conceived naturally. They reported gains on a personal level, interpersonal level and transpersonal level through surviving the experience of infertility. All, regardless of the eventual outcome, reported at least one form of personal gain: in personality or knowledge gain. Interpersonal gains were perceived in relationships with their spouses, children, parents, friends, colleagues and fellow IVF service users. More than half of them reported spiritual growth and a change in identity through integrating their experiences and offering help to others. Despite the small sample size, this study makes a significant contribution by suggesting that while negative feelings provoked by the failure to conceive should be acknowledged, people in this situation should also be enabled to consolidate their negative experiences of IVF constructively, helping them to move on with their lives.

  4. Experience gained in the process of the variable mass heat flow control implemented in the district heat supply system of the city of Gyor

    Energy Technology Data Exchange (ETDEWEB)

    Nagy, F.; Milanovich, L.; Lelek, J.; Kekk, I. [District Heating LTD. of Gyor (Hungary)

    1996-11-01

    The district heating system of the city of Gyor is fed from a hot water boiler plant. The total heat demand for 23,000 residential homes and several public facilities is 260 MW. The variable mass flow control was implemented in 1991 through 1992. Design, preparatory job and the majority of implementation was carried out without external involvement. The paper presents historical background and brief project presentation which is followed by comparative presentation of the variable mass flow control and constant mass flow control. This comparative survey has been conducted on the basis of operating data for 1993 and those for 1988. In the conclusion the gained experience is summarized.

  5. Gain control mechanisms in spinal motoneurons

    Directory of Open Access Journals (Sweden)

    Michael David Johnson

    2014-07-01

    Full Text Available Motoneurons provide the only conduit for motor commands to reach muscles. For many years, motoneurons were in fact considered to be little more than passive wires. Systematic studies in the past 25 years however have clearly demonstrated that the intrinsic electrical properties of motoneurons are under strong neuromodulatory control via multiple sources. The discovery of potent neuromodulation from the brainstem and its ability to change the gain of motoneurons shows that the passive view of the motor output stage is no longer tenable. A mechanism for gain control at the motor output stage makes good functional sense considering our capability of generating an enormous range of forces, from very delicate (e.g. putting in a contact lens to highly forceful (emergency reactions. Just as sensory systems need gain control to deal with a wide dynamic range of inputs, so to might motor output need gain control to deal with the wide dynamic range of the normal movement repertoire. Two problems emerge from the potential use of the brainstem monoaminergic projection to motoneurons for gain control. First, the projection is highly diffuse anatomically, so that independent control of the gains of different motor pools is not feasible. In fact, the system is so diffuse that gain for all the motor pools in a limb likely increases in concert. Second, if there is a system that increases gain, probably a system to reduce gain is also needed. In this review, we summarize recent studies that show local inhibitory circuits within the spinal cord, especially reciprocal and recurrent inhibition, have the potential to solve both of these problems as well as constitute another source of gain modulation.

  6. Short-Term Study Abroad: Perspectives on Speaking Gains and Language Contact

    Science.gov (United States)

    Hernández, Todd A.

    2016-01-01

    Previous studies have shown that study abroad has a positive effect on second language (L2) learning outcomes for students who spend at least a semester abroad. It is unclear, however, whether a short-term experience also has a measurable impact on L2 development. The present study examines the relationship between speaking proficiency gains made…

  7. Sensitivity and environmental response of the CMS RPC gas gain monitoring system

    CERN Document Server

    Benussi, L.; Colafranceschi, S.; Fabbri, F.L.; Giardoni, M.; Ortenzi, B.; Paolozzi, A.; Passamonti, L.; Pierluigi, D.; Ponzio, B.; Russo, A.; Colaleo, A.; Loddo, F.; Maggi, M.; Ranieri, A.; Abbrescia, M.; Iaselli, G.; Marangelli, B.; Natali, S.; Nuzzo, S.; Pugliese, G.; Romano, F.; Roselli, G.; Trentadue, R.; Tupputi, S.; Guida, R.; Polese, G.; Sharma, A.; Cimmino, A.; Lomidze, D.; Paolucci, D.; Piccolo, P.; Baesso, P.; Necchi, M.; Pagano, D.; Ratti, S.P.; Vitulo, P.; Viviani, C.

    Results from the gas gain monitoring (GGM) system for the muon detector using RPC in the CMS experiment at the LHC is presented. The system is designed to provide fast and accurate determination of any shift in the working point of the chambers due to gas mixture changes.

  8. Receiver Gain Modulation Circuit

    Science.gov (United States)

    Jones, Hollis; Racette, Paul; Walker, David; Gu, Dazhen

    2011-01-01

    A receiver gain modulation circuit (RGMC) was developed that modulates the power gain of the output of a radiometer receiver with a test signal. As the radiometer receiver switches between calibration noise references, the test signal is mixed with the calibrated noise and thus produces an ensemble set of measurements from which ensemble statistical analysis can be used to extract statistical information about the test signal. The RGMC is an enabling technology of the ensemble detector. As a key component for achieving ensemble detection and analysis, the RGMC has broad aeronautical and space applications. The RGMC can be used to test and develop new calibration algorithms, for example, to detect gain anomalies, and/or correct for slow drifts that affect climate-quality measurements over an accelerated time scale. A generalized approach to analyzing radiometer system designs yields a mathematical treatment of noise reference measurements in calibration algorithms. By treating the measurements from the different noise references as ensemble samples of the receiver state, i.e. receiver gain, a quantitative description of the non-stationary properties of the underlying receiver fluctuations can be derived. Excellent agreement has been obtained between model calculations and radiometric measurements. The mathematical formulation is equivalent to modulating the gain of a stable receiver with an externally generated signal and is the basis for ensemble detection and analysis (EDA). The concept of generating ensemble data sets using an ensemble detector is similar to the ensemble data sets generated as part of ensemble empirical mode decomposition (EEMD) with exception of a key distinguishing factor. EEMD adds noise to the signal under study whereas EDA mixes the signal with calibrated noise. It is mixing with calibrated noise that permits the measurement of temporal-functional variability of uncertainty in the underlying process. The RGMC permits the evaluation of EDA by

  9. Use of knowledge and experience gained from the Fukushima Daiichi Nuclear Power Station accident to establish the technical basis for strategic off-site response

    International Nuclear Information System (INIS)

    Miyahara, Kaname; Saito, Kimiaki; Iijima, Kazuki; McKinley, Ian; Hardie, Susan

    2015-03-01

    This report provides a concise overview of knowledge and experience gained from the activities for environmental remediation after the Fukushima Daiichi (1F) accident. It is specifically tailored for international use, to establish or refine the technical basis for strategic, off-site response to nuclear incidents. It reflects JAEA's key role in the research associated with both remediation of contaminated areas and also the natural contamination migration processes in non-remediated areas, in collaboration with other Japanese and international organisations and research institutes. Environmental monitoring and mapping to define boundary conditions in terms of the distribution of radioactivity and resultant doses, guides the resultant response. Radiation protection considerations set constraints, with approaches developed to estimate doses to different critical groups and set appropriate dose reduction targets. Decontamination activities, with special emphasis on associated waste management, provide experience in evaluation of the effectiveness of decontamination and the pros and cons of different approaches / technologies. The assessment of the natural behaviour of contaminant radionuclides and their mobility in the environment is now focused almost entirely on radiocaesium. Here, the impact of natural mobility in terms of self-cleaning / re-concentration in cleaned areas is discussed, along with possible actions to modify such transport or manage potential areas of radiocaesium accumulation. Many of the conditions in Fukushima are similar to those following past contamination events in other countries, where natural self-cleaning alone has allowed recovery to such an extent that the original incident is now largely forgotten. Decontamination efforts in Japan will certainly accelerate this process. On-going remediation work is based on a good technical understanding of the movement of radiocaesium in the environment and this understanding is being translated into

  10. Rapid growth in early childhood associated with young adult overweight and obesity--evidence from a community based cohort study.

    Science.gov (United States)

    Sutharsan, Ratneswary; O'Callaghan, Michael J; Williams, Gail; Najman, Jake M; Mamun, Abdullah A

    2015-08-08

    Rapid weight gain in early life may increase the risk of overweight and obesity in adulthood. We investigated the association between the rate of growth during early childhood and the development of overweight and obesity in young adults. We used a prospective cohort study of 2077 young adults who were born between 1981 and 1984 in Brisbane, Australia and had anthropometry measurements available at birth, 6 months, 5 years, 14 years and 21 years of age. The associations of rate of early growth with body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) and their categories at 21 years were studied using multivariate analysis. We found that rapid weight gain [> + 0.67 standard deviation score (SDS)] in the first 5 years of life was associated with young adults' overweight status (BMI: adjusted OR = 2.35, 95% CI, 1.82-3.03; WC: adjusted OR = 2.20, 95% CI, 1.65-2.95). We also observed that slow weight gain in the first 5 years of age (young adulthood, in contrast slow weight gain was inversely associated with weight status at 21 years.

  11. Sweet taste of saccharin induces weight gain without increasing caloric intake, not related to insulin-resistance in Wistar rats.

    Science.gov (United States)

    Foletto, Kelly Carraro; Melo Batista, Bruna Aparecida; Neves, Alice Magagnin; de Matos Feijó, Fernanda; Ballard, Cíntia Reis; Marques Ribeiro, Maria Flávia; Bertoluci, Marcello Casaccia

    2016-01-01

    In a previous study, we showed that saccharin can induce weight gain when compared with sucrose in Wistar rats despite similar total caloric intake. We now question whether it could be due to the sweet taste of saccharin per se. We also aimed to address if this weight gain is associated with insulin-resistance and to increases in gut peptides such as leptin and PYY in the fasting state. In a 14 week experiment, 16 male Wistar rats received either saccharin-sweetened yogurt or non-sweetened yogurt daily in addition to chow and water ad lib. We measured daily food intake and weight gain weekly. At the end of the experiment, we evaluated fasting leptin, glucose, insulin, PYY and determined insulin resistance through HOMA-IR. Cumulative weight gain and food intake were evaluated through linear mixed models. Results showed that saccharin induced greater weight gain when compared with non-sweetened control (p = 0.027) despite a similar total caloric intake. There were no differences in HOMA-IR, fasting leptin or PYY levels between groups. We conclude that saccharin sweet taste can induce mild weight gain in Wistar rats without increasing total caloric intake. This weight gain was not related with insulin-resistance nor changes in fasting leptin or PYY in Wistar rats. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. The French experience

    CERN Document Server

    Bougard, Marie-Thérèse

    2003-01-01

    Developed for beginners, The French Experience 1 course book is designed to accompany the French Experience 1 CDs (9780563472582) but can also be used on its own to develop your reading and writing skills. You’ll gain valuable insights into French culture too.

  13. Undergraduate experiments on statistical optics

    International Nuclear Information System (INIS)

    Scholz, Ruediger; Friege, Gunnar; Weber, Kim-Alessandro

    2016-01-01

    Since the pioneering experiments of Forrester et al (1955 Phys. Rev. 99 1691) and Hanbury Brown and Twiss (1956 Nature 177 27; Nature 178 1046), along with the introduction of the laser in the 1960s, the systematic analysis of random fluctuations of optical fields has developed to become an indispensible part of physical optics for gaining insight into features of the fields. In 1985 Joseph W Goodman prefaced his textbook on statistical optics with a strong commitment to the ‘tools of probability and statistics’ (Goodman 2000 Statistical Optics (New York: John Wiley and Sons Inc.)) in the education of advanced optics. Since then a wide range of novel undergraduate optical counting experiments and corresponding pedagogical approaches have been introduced to underpin the rapid growth of the interest in coherence and photon statistics. We propose low cost experimental steps that are a fair way off ‘real’ quantum optics, but that give deep insight into random optical fluctuation phenomena: (1) the introduction of statistical methods into undergraduate university optical lab work, and (2) the connection between the photoelectrical signal and the characteristics of the light source. We describe three experiments and theoretical approaches which may be used to pave the way for a well balanced growth of knowledge, providing students with an opportunity to enhance their abilities to adapt the ‘tools of probability and statistics’. (paper)

  14. JINR rapid communications

    International Nuclear Information System (INIS)

    1996-01-01

    The present collection of rapid communications from JINR, Dubna, contains seven separate reports on the identification of events with a secondary vertex in the experiment EXCHARM, the zero degree calorimeter for CERN WA-98 experiment, a new approach to increase the resource of installation elements for super-high energy physics, a method of the in-flight production of exotic systems in the charge-exchange reactions, the neutron activation analysis for monitoring northern terrestrial ecosystems, a search for 28 O and study of the neutron-rich nuclei near the neutron closure N=20, a search for new neutron-rich nuclei with a 70A MeV 48 Ca beam. 33 figs., 4 tabs

  15. JINR rapid communications

    International Nuclear Information System (INIS)

    1997-01-01

    The present collection of rapid communications from JINR, Dubna, contains seven separate reports on observation of transversal handedness in the diffractive production of pion triples, a possible experiment on the research of dibaryon states, Cherenkov beam counter system of the CERES/NA45 spectrometer for investigation with 160 GeV/n. lead ions, a profile-based gaseous detector with capacitive pad readout as the prototype of the shower maximum detector for the end-cap electromagnetic calorimeter for the STAR experiment, what DELPHI can get with an upgraded position for the very small angle tagger, estimation of the radiation environment and the shielding aspect for the point 2 area of the LHC and the orthopositronium decay puzzle

  16. Energy Gaining Windows for Residental Buildings

    DEFF Research Database (Denmark)

    Kragh, Jesper; Laustsen, Jacob Birck; Svendsen, Svend

    2008-01-01

    This paper presents some of the research done during the last 8 years at the Technical University of Denmark developing improved low-energy window solutions. The focus has been on maximizing the net energy gain of windows for residential buildings. The net energy gain of windows is the solar gain...... minus the heat loss integrated over the heating season. It is assumed that in northern cold climates all of the solar gain during the heating season can be utilized for space heating. Problems with overheating in the summer period must be solved with overhang or moveable solar shading devices. Two...... and longer durability of the window. The glazing in these fiber reinforced polyester windows is both unsealed and sealed triple glazing units. To increase the net energy gain slim frame profiles have been developed to increase the glazing area and thereby the solar gain. The challenge when developing slim...

  17. RapidIO as a multi-purpose interconnect

    Science.gov (United States)

    Baymani, Simaolhoda; Alexopoulos, Konstantinos; Valat, Sébastien

    2017-10-01

    RapidIO (http://rapidio.org/) technology is a packet-switched high-performance fabric, which has been under active development since 1997. Originally meant to be a front side bus, it developed into a system level interconnect which is today used in all 4G/LTE base stations world wide. RapidIO is often used in embedded systems that require high reliability, low latency and scalability in a heterogeneous environment - features that are highly interesting for several use cases, such as data analytics and data acquisition (DAQ) networks. We will present the results of evaluating RapidIO in a data analytics environment, from setup to benchmark. Specifically, we will share the experience of running ROOT and Hadoop on top of RapidIO. To demonstrate the multi-purpose characteristics of RapidIO, we will also present the results of investigating RapidIO as a technology for high-speed DAQ networks using a generic multi-protocol event-building emulation tool. In addition we will present lessons learned from implementing native ports of CERN applications to RapidIO.

  18. A new facility for rapid neutron activation analysis

    International Nuclear Information System (INIS)

    Zeisler, R.; Makarewicz, M.; Grass, F.; Casta, J.

    1996-01-01

    Many research groups have undertaken efforts on the utilization of short-lived nuclides in a broad spectrum of neutron activation analysis (NAA) applications. The advantages of these approaches are obvious because the information on the sample can be extracted more rapidly. In addition to its other advantages, NAA can become extremely competitive in price and analysis time. Nevertheless, NAA with short-lived nuclides has not gained broad popularity, perhaps because of some difficulties in accuracy and the availability of suitable irradiation facilities. This report discusses the ASTRA reactor for neutron activation analysis capabilities

  19. Is wartime mobilisation a suitable policy model for rapid national climate mitigation?

    International Nuclear Information System (INIS)

    Delina, Laurence L.; Diesendorf, Mark

    2013-01-01

    Climate science suggests that, to have a high probability of limiting global warming to an average temperature increase of 2 °C, global greenhouse gas emissions must peak by 2020 and be reduced to close to zero by 2040. However, the current trend is heading towards at least 4 °C by 2100 and little effective action is being taken. This paper commences the process of developing contingency plans for a scenario in which a sudden major global climate impact galvanises governments to implement emergency climate mitigation targets and programs. Climate activists assert that rapid mitigation is feasible, invoking the scale and scope of wartime mobilisation strategies. This paper draws upon historical accounts of social, technological and economic restructurings in several countries during World War 2 in order to investigate potential applications of wartime experience to radical, rigorous and rapid climate mitigation strategies. We focus on the energy sector, the biggest single contributor to global climate change, in developed and rapidly developing countries. We find that, while wartime experience suggests some potential strategies for rapid climate mitigation in the areas of finance and labour, it also has severe limitations, resulting from its lack of democratic processes. - Highlights: • The paper explores the strengths and weaknesses of using wartime experience as a model for rapid climate mitigation. • Wartime experience suggests some potential strategies for rapid climate mitigation in the areas of finance and labour. • Wartime experience also has severe limitations, resulting from its lack of democratic processes

  20. Optimal weight gain in triplet pregnancies.

    Science.gov (United States)

    Johnston, Robert C; Erfani, Hadi; Shamshirsaz, Amir A; Spiel, Melissa; Ravangard, Sam F; Shaman, Majid; Allaf, M Baraa; Shamshirsaz, Alireza A; Haeri, Sina

    2017-08-01

    To identify appropriate weight gain in triplet gestations, which may aid in reducing the risk of perinatal morbidity within this high-risk cohort. This retrospective cohort study evaluated all non-anomalous triplet pregnancies between 23 and 40 weeks' gestation resulting in live births at five tertiary-care medical centers between 1991 and 2011. Subjects were divided by pre-pregnancy BMI into underweight, normal-weight, overweight, and obese groups, and then stratified by low (gain (≥1.5 lbs/week). Primary outcomes included spontaneous preterm birth and preeclampsia. We included 116 mothers and 348 corresponding neonates for final analysis. The incidence of preeclampsia and preterm delivery less than 32 weeks' gestation was 37% and 41%, respectively. The incidence of preeclampsia increased with weight gain per week, but was not statistically different from subjects who gained less weight. We found no statistical correlation between weight gain per week and preterm delivery. We found no association between preeclampsia or preterm delivery and increasing weight gain in triplet pregnancies. The association with increased risk for preeclampsia was predominantly due to BMI effect. Based on the current study, recommendations for optimal weight gain in mothers with triplet gestations could not be defined.

  1. EXPERIENCE WITH RAPTEN RAPID USING IN THE TREATMENT OF ARTICULAR SYNDROME IN RHEUMATOID ARTHRITIS

    Directory of Open Access Journals (Sweden)

    A. B. Zborovsky

    2001-01-01

    Full Text Available Summary Our aim was to study the clinical efjicacy of Rapten rapid, its effect on the activity of inflammatory process, parameters of immunity in rheumatoid arthritis as compared with other widely used NSAIDs: sodium diclofenac, Indometacin, Ibuprofen and also to clarify the mechanism of action of above drugs. The study included 110 RA patients which were divided into 4 groups. Pts of the I s' group toolc Rapten rapid (n=50, 2 ml - sodium diclofenac (n—20, 3d - Indometacin (n—20, 4' h - Ibuprofen (n—20. Al the result of the study it was found that Rapten rapid effectively reduces pain syndrome in rheumatoid arthritis, does not give preference to other anti-inflammatory drugs on analgetic and anti-inflammatory effect, has positive influence on laboratory indices of inflammation rendering thus more speedy analgetic effect demonstrated averagely 2 days faster as compared with other NSAJDs. Frequency of side-effects during Rapten rapid application does not reliably differ from other NSAIDs. Rapten rapid possesses immunomodulatory effect demonstrated by decreasing the level of serum IgA, activity of 5‘nucleotidase in lymphocytes, neutrophils, monocytes and myeloperoxidase in monocytes.

  2. Reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report

    Directory of Open Access Journals (Sweden)

    Okazaki K

    2017-11-01

    Full Text Available Kosuke Okazaki, Kazuhiko Yamamuro, Toshifumi Kishimoto Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Japan Aims: Antipsychotics are effective for treating schizophrenia, but atypical antipsychotics can cause several adverse side effects including weight gain, hyperprolactinemia, and extrapyramidal symptoms. Moreover, weight gain increases the risk of metabolic diseases.Methods: We treated a case of olanzapine-induced weight gain in a 41-year-old man with schizophrenia by switching his medication from olanzapine to asenapine.Results: The weight gain improved after switching the medication, from 80.3 to 75.0 kg, a weight loss of 6.6%, and there was no significant worsening of psychological symptoms or other adverse effects.Conclusions: Asenapine might be effective for treating patients with schizophrenia who experience olanzapine-induced weight gain. Keywords: olanzapine, weight gain, schizophrenia, asenapine

  3. Weight suppression predicts total weight gain and rate of weight gain in outpatients with anorexia nervosa.

    Science.gov (United States)

    Carter, Frances A; Boden, Joseph M; Jordan, Jennifer; McIntosh, Virginia V W; Bulik, Cynthia M; Joyce, Peter R

    2015-11-01

    The present study sought to replicate the finding of Wildes and Marcus, Behav Res Ther, 50, 266-274, 2012 that higher levels of weight suppression at pretreatment predict greater total weight gain, faster rate of weight gain, and bulimic symptoms amongst patients admitted with anorexia nervosa. Participants were 56 women with anorexia nervosa diagnosed by using strict or lenient weight criteria, who were participating in a randomized controlled psychotherapy trial (McIntosh et al., Am J Psychiatry, 162, 741-747, 2005). Thirty-five women completed outpatient treatment and post-treatment assessment. Weight suppression was the discrepancy between highest lifetime weight at adult height and weight at pretreatment assessment. Outcome variables were total weight gain, rate of weight gain, and bulimic symptoms in the month prior to post-treatment assessment [assessed using the Eating Disorders Examination (Fairburn et al., Binge-Eating: Nature, Assessment and Treatment. New York: Guilford, 1993)]. Weight suppression was positively associated with total weight gain and rate of weight gain over treatment. Regression models showed that this association could not be explained by covariates (age at onset of anorexia nervosa and treatment modality). Weight suppression was not significantly associated with bulimic symptoms in the month prior to post-treatment assessment, regardless of whether bulimic symptoms were examined as continuous or dichotomous variables. The present study reinforces the previous finding that weight suppression predicts total weight gain and rate of weight gain amongst patients being treated for anorexia nervosa. Methodological issues may explain the failure of the present study to find that weight suppression predicts bulimic symptoms. Weight suppression at pretreatment for anorexia nervosa should be assessed routinely and may inform treatment planning. © 2015 Wiley Periodicals, Inc.

  4. BN-600 power unit 15-year operating experience

    International Nuclear Information System (INIS)

    Saraev, O.M.; Oshkanov, N.N.; Vylomov, V.V.

    1996-01-01

    Comprehensive experience has been gained with the operating fast reactor BN-600 with a power out of 600 MWe. This paper includes important performance results and gives also an overview of the experience gained from BN-600 NPP commercial operation during 15 years. (author). 2 figs, 1 tab

  5. Measurement of Antenna Bore-Sight Gain

    Science.gov (United States)

    Fortinberry, Jarrod; Shumpert, Thomas H.

    2016-01-01

    The absolute or free-field gain of a simple antenna can be approximated using standard antenna theory formulae or for a more accurate prediction, numerical methods may be employed to solve for antenna parameters including gain. Both of these methods will result in relatively reasonable estimates but in practice antenna gain is usually verified and documented via measurements and calibration. In this paper, a relatively simple and low-cost, yet effective means of determining the bore-sight free-field gain of a VHF/UHF antenna is proposed by using the Brewster angle relationship.

  6. Experiences gained in implementing a broad-based risk-informed application

    International Nuclear Information System (INIS)

    Schinzel, G.E.

    2004-01-01

    The South Texas Project was granted a first-of-kind exemption from special treatment requirements contained in 10-CFR Parts 21, 50, and 100 in August 2001. Since that time, South Texas has pursued a cautious, deliberate approach to implement these risk-informed exemption allowances. Over the past two years, South Texas has gained a unique insight into the challenges and benefits that exist in pursuing a broad-based risk-informed application. The American nuclear industry is currently pursuing similar capabilities through proposed rule 10-CFR 50.69 which is scheduled for NRC final review and approval in the July, 2004 time-frame. This proposed rule closely resembles the approach taken by South Texas in the exemption process and the allowances granted. For nuclear utilities that wish to pursue a similar broad-based risk-informed application, a well-conceived strategic approach is needed to prioritize the implementation activities as well as engage stake-holders in the implementation process. Cultural and communication challenges exist which must be addressed and effectively overcome. The goal of this paper is to communicate these challenges to the attendees, inform attendees of the safety and economic benefits to be recognized through this risk-informed approach, and to provide insight into continuing application opportunities that were not readily apparent when the broad-based exemption was originally conceived. This paper and presentation will be beneficial for both domestic and international attendees, as well as for personnel with utility or regulatory backgrounds. (author)

  7. Gain scheduling using the Youla parameterization

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik; Stoustrup, Jakob

    1999-01-01

    Gain scheduling controllers are considered in this paper. The gain scheduling problem where the scheduling parameter vector cannot be measured directly, but needs to be estimated is considered. An estimation of the scheduling vector has been derived by using the Youla parameterization. The use...... in connection with H_inf gain scheduling controllers....

  8. High Gain Advanced GPS Receiver

    National Research Council Canada - National Science Library

    Brown, Alison; Zhang, Gengsheng

    2006-01-01

    NAVSYS High Gain Advanced GPS Receiver (HAGR) uses a digital beam-steering antenna array to enable up to eight GPS satellites to be tracked, each with up to 10 dBi of additional antenna gain over a conventional receiver solution...

  9. New results of the high-gain harmonic generation free-electron laser experiment

    International Nuclear Information System (INIS)

    Doyuran, A.; Babzien, M.; Shaftan, T.; Biedron, S.G.; Yu, L.H.; Ben-Zvi, I.; DiMauro, L.F.; Graves, W.; Johnson, E.; Krinsky, S.; Malone, R.; Pogorelsky, I.; Skaritka, J.; Rakowsky, G.; Wang, X.J.; Woodle, M.; Yakimenko, V.; Jagger, J.; Sajaev, V.; Vasserman, I.

    2001-01-01

    We report on the experimental investigation of high-gain harmonic generation carried out at the Accelerator Test Facility at Brookhaven National Laboratory. A seed CO 2 laser at a wavelength of 10.6 μm was used to generate FEL output at a 5.3-μm wavelength. The duration of the output pulse was measured using a second-harmonic intensity autocorrelator, and the coherence length was measured using an interferometer. We also measured the energy distribution of the electron beam after it exited the second undulator, observing behavior consistent with that is expected at saturation. The intensity of the harmonic components of the output at 2.65 and 1.77 μm was determined relative to that of the 5.3-μm fundamental. Finally, using a corrector magnet upstream of the radiator, steering effects on the trajectories of the electron and light beams were studied

  10. Relative contributions of energy expenditure on physical activity, body composition and weight gain to the evolution of impaired glucose tolerance to Frank diabetes

    International Nuclear Information System (INIS)

    Forrester, T.; Wilks, R.; Jahoor, F.; Adeyemo, A.

    1999-01-01

    In modem technological societies the requirement for physical work is diminished and access to food is unrestricted. Under these circumstances a large proportion of the population will gain weight and develop obesity and diabetes. At the individual level, genetic and behavioural factors must combine to lead to an imbalance between energy intake and its expenditure. Weight gain, especially rapid weight gain in a population appears to increase the risk of diabetes sharply. Thus understanding the route to weight gain and obesity, and the modulatory effects of physical activity on development of glucose intolerance is critical to credible intervention strategies to reverse or prevent diabetes in populations especially those in transitional societies. In this proposal we will examine the quantitative importance of non-resting energy expenditure (EE) in populations with rising levels of obesity and high prevalence of diabetes. (author)

  11. Determination of the STIS CCD Gain

    Science.gov (United States)

    Riley, Allyssa; Monroe, TalaWanda; Lockwood, Sean

    2016-09-01

    This report summarizes the analysis and absolute gain results of the STIS Cycle 23 special calibration program 14424 that was designed to measure the gain of amplifiers A, C and D at nominal gain settings of 1 and 4 e-/DN. We used the mean-variance technique and the results indicate a mean-variance technique.

  12. Multimodal Pilot Behavior in Multi-Axis Tracking Tasks with Time-Varying Motion Cueing Gains

    Science.gov (United States)

    Zaal, P. M. T; Pool, D. M.

    2014-01-01

    In a large number of motion-base simulators, adaptive motion filters are utilized to maximize the use of the available motion envelope of the motion system. However, not much is known about how the time-varying characteristics of such adaptive filters affect pilots when performing manual aircraft control. This paper presents the results of a study investigating the effects of time-varying motion filter gains on pilot control behavior and performance. An experiment was performed in a motion-base simulator where participants performed a simultaneous roll and pitch tracking task, while the roll and/or pitch motion filter gains changed over time. Results indicate that performance increases over time with increasing motion gains. This increase is a result of a time-varying adaptation of pilots' equalization dynamics, characterized by increased visual and motion response gains and decreased visual lead time constants. Opposite trends are found for decreasing motion filter gains. Even though the trends in both controlled axes are found to be largely the same, effects are less significant in roll. In addition, results indicate minor cross-coupling effects between pitch and roll, where a cueing variation in one axis affects the behavior adopted in the other axis.

  13. Rates of mass gain and energy deposition in red knot on their final spring staging site is both time- and condition-dependent

    NARCIS (Netherlands)

    Atkinson, Philip W.; Baker, Allan J.; Bennett, Karen A.; Clark, Nigel A.; Clark, Jacquie A.; Cole, Kimberly B.; Dekinga, Anne; Dey, Amanda; Gillings, Simon; Gonzalez, Patricia M.; Kalasz, Kevin; Minton, Clive D. T.; Newton, Jason; Niles, Lawrence J.; Piersma, Theunis; Robinson, Robert A.; Sitters, Humphrey P.; Stevens, Phil

    1. Millions of shorebirds migrate each year through a small number of highly productive staging areas where they often conflict with fisheries interests. Delaware Bay, USA, is a major shorebird stopover site where, in spring, many thousands of shorebirds undergo rapid mass gain by feeding on the

  14. Resolved discrepancies between visible spontaneous Raman cross-section and direct near-infrared Raman gain measurements in TeO2-based glasses.

    Science.gov (United States)

    Rivero, Clara; Stegeman, Robert; Couzi, Michel; Talaga, David; Cardinal, Thierry; Richardson, Kathleen; Stegeman, George

    2005-06-13

    Disagreements on the Raman gain response of different tellurite-based glasses, measured at different wavelengths, have been recently reported in the literature. In order to resolve this controversy, a multi-wavelength Raman cross-section experiment was conducted on two different TeO2-based glass samples. The estimated Raman gain response of the material shows good agreement with the directly-measured Raman gain data at 1064 nm, after correction for the dispersion and wavelength-dependence of the Raman gain process.

  15. Nonunity gain minimal-disturbance measurement

    DEFF Research Database (Denmark)

    Sabuncu, Metin; Mišta, L.; Fiurášek, J.

    2007-01-01

    We propose and experimentally demonstrate an optimal nonunity gain Gaussian scheme for partial measurement of an unknown coherent state that causes minimal disturbance of the state. The information gain and the state disturbance are quantified by the noise added to the measurement outcomes...

  16. Binocular contrast-gain control for natural scenes: Image structure and phase alignment.

    Science.gov (United States)

    Huang, Pi-Chun; Dai, Yu-Ming

    2018-05-01

    In the context of natural scenes, we applied the pattern-masking paradigm to investigate how image structure and phase alignment affect contrast-gain control in binocular vision. We measured the discrimination thresholds of bandpass-filtered natural-scene images (targets) under various types of pedestals. Our first experiment had four pedestal types: bandpass-filtered pedestals, unfiltered pedestals, notch-filtered pedestals (which enabled removal of the spatial frequency), and misaligned pedestals (which involved rotation of unfiltered pedestals). Our second experiment featured six types of pedestals: bandpass-filtered, unfiltered, and notch-filtered pedestals, and the corresponding phase-scrambled pedestals. The thresholds were compared for monocular, binocular, and dichoptic viewing configurations. The bandpass-filtered pedestal and unfiltered pedestals showed classic dipper shapes; the dipper shapes of the notch-filtered, misaligned, and phase-scrambled pedestals were weak. We adopted a two-stage binocular contrast-gain control model to describe our results. We deduced that the phase-alignment information influenced the contrast-gain control mechanism before the binocular summation stage and that the phase-alignment information and structural misalignment information caused relatively strong divisive inhibition in the monocular and interocular suppression stages. When the pedestals were phase-scrambled, the elimination of the interocular suppression processing was the most convincing explanation of the results. Thus, our results indicated that both phase-alignment information and similar image structures cause strong interocular suppression. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. Energy gains from lattice-enabled nuclear reactions

    International Nuclear Information System (INIS)

    Nagel, David J.

    2015-01-01

    The energy gain of a system is defined as the ratio of its output energy divided by the energy provided to operate the system. Most familiar systems have energy gains less than one due to various inefficiencies. By contrast, lattice-enabled nuclear reactions (LENR) offer high energy gains. Theoretical values in excess of 1000 are possible. Energy gains over 100 have already been reported. But, they have not yet been sustained for commercially significant durations. This article summarizes the current status of LENR energy gains. (author)

  18. Gaining Efficiency of Computational Experiments in Modeling the Flight Vehicle Movement

    Directory of Open Access Journals (Sweden)

    I. K. Romanova

    2017-01-01

    Full Text Available The paper considers one of the important aspects to gain efficiency of conducted computational experiments, namely to provide grid optimization. The problem solution will ultimately create a more perfect system, because just a multivariate simulation is a basis to apply optimization methods by the specified criteria and to identify problems in functioning of technical systems.The paper discusses a class of the moving objects, representing a body of revolution, which, for one reason or another, endures deformation of casing. Analyses using the author's techniques have shown that there are the following complex functional dependencies of aerodynamic characteristics of the studied class of deformed objects.Presents a literature review on new ways for organizing the calculations, data storage and transfer. Provides analysing the methods of forming grids, including those used in initial calculations and visualization of information. In addition to the regular grids, are offered unstructured grids, including those for dynamic spatial-temporal information. Attention is drawn to the problem of an efficient retrieval of information. The paper shows a relevant capability to run with large data volumes, including an OLAP technology, multidimensional cubes (Data Cube, and finally, an integrated Date Mining approach.Despite the huge number of successful modern approaches to the solution of problems of formation, storage and processing of multidimensional data, it should be noted that computationally these tools are quite expensive. Expenditure for using the special tools often exceeds the cost of directly conducted computational experiments as such. In this regard, it was recognized that it is unnecessary to abandon the use of traditional tools and focus on a direct increase of their efficiency. Within the framework of the applied problem under consideration such a tool was to form the optimal grids.The optimal grid was understood to be a grid in the N

  19. Charge Gain, Voltage Gain, and Node Capacitance of the SAPHIRA Detector Pixel by Pixel

    Science.gov (United States)

    Pastrana, Izabella M.; Hall, Donald N. B.; Baker, Ian M.; Jacobson, Shane M.; Goebel, Sean B.

    2018-01-01

    The University of Hawai`i Institute for Astronomy has partnered with Leonardo (formerly Selex) in the development of HgCdTe linear mode avalanche photodiode (L-APD) SAPHIRA detectors. The SAPHIRA (Selex Avalanche Photodiode High-speed Infra-Red Array) is ideally suited for photon-starved astronomical observations, particularly near infrared (NIR) adaptive optics (AO) wave-front sensing. I have measured the stability, and linearity with current, of a 1.7-um (10% spectral bandpass) infrared light emitting diode (IR LED) used to illuminate the SAPHIRA and have then utilized this source to determine the charge gain (in e-/ADU), voltage gain (in uV/ADU), and node capacitance (in fF) for each pixel of the 320x256@24um SAPHIRA. These have previously only been averages over some sub-array. Determined from the ratio of the temporal averaged signal level to variance under constant 1.7-um LED illumination, I present the charge gain pixel-by-pixel in a 64x64 sub-array at the center of the active area of the SAPHIRA (analyzed separately as four 32x32 sub-arrays) to be about 1.6 e-/ADU (σ=0.5 e-/ADU). Additionally, the standard technique of varying the pixel reset voltage (PRV) in 10 mV increments and recording output frames for the same 64x64 subarray found the voltage gain per pixel to be about 11.7 uV/ADU (σ=0.2 uV/ADU). Finally, node capacitance was found to be approximately 23 fF (σ=6 fF) utilizing the aforementioned charge and voltage gain measurements. I further discuss the linearity measurements of the 1.7-um LED used in the charge gain characterization procedure.

  20. Gain- and Loss-Related Brain Activation Are Associated with Information Search Differences in Risky Gambles: An fMRI and Eye-Tracking Study.

    Science.gov (United States)

    Häusler, Alexander Niklas; Oroz Artigas, Sergio; Trautner, Peter; Weber, Bernd

    2016-01-01

    People differ in the way they approach and handle choices with unsure outcomes. In this study, we demonstrate that individual differences in the neural processing of gains and losses relates to attentional differences in the way individuals search for information in gambles. Fifty subjects participated in two independent experiments. Participants first completed an fMRI experiment involving financial gains and losses. Subsequently, they performed an eye-tracking experiment on binary choices between risky gambles, each displaying monetary outcomes and their respective probabilities. We find that individual differences in gain and loss processing relate to attention distribution. Individuals with a stronger reaction to gains in the ventromedial prefrontal cortex paid more attention to monetary amounts, while a stronger reaction in the ventral striatum to losses was correlated with an increased attention to probabilities. Reaction in the posterior cingulate cortex to losses was also found to correlate with an increased attention to probabilities. Our data show that individual differences in brain activity and differences in information search processes are closely linked.

  1. Matching time and spatial scales of rapid solidification: dynamic TEM experiments coupled to CALPHAD-informed phase-field simulations

    Science.gov (United States)

    Perron, Aurelien; Roehling, John D.; Turchi, Patrice E. A.; Fattebert, Jean-Luc; McKeown, Joseph T.

    2018-01-01

    A combination of dynamic transmission electron microscopy (DTEM) experiments and CALPHAD-informed phase-field simulations was used to study rapid solidification in Cu-Ni thin-film alloys. Experiments—conducted in the DTEM—consisted of in situ laser melting and determination of the solidification kinetics by monitoring the solid-liquid interface and the overall microstructure evolution (time-resolved measurements) during the solidification process. Modelling of the Cu-Ni alloy microstructure evolution was based on a phase-field model that included realistic Gibbs energies and diffusion coefficients from the CALPHAD framework (thermodynamic and mobility databases). DTEM and post mortem experiments highlighted the formation of microsegregation-free columnar grains with interface velocities varying from ˜0.1 to ˜0.6 m s-1. After an ‘incubation’ time, the velocity of the planar solid-liquid interface accelerated until solidification was complete. In addition, a decrease of the temperature gradient induced a decrease in the interface velocity. The modelling strategy permitted the simulation (in 1D and 2D) of the solidification process from the initially diffusion-controlled to the nearly partitionless regimes. Finally, results of DTEM experiments and phase-field simulations (grain morphology, solute distribution, and solid-liquid interface velocity) were consistent at similar time (μs) and spatial scales (μm).

  2. Approaches to gaining public acceptance of repository siting

    International Nuclear Information System (INIS)

    Numark, N.J.; Wonder, E.F.

    1989-01-01

    An eight-country survey reveals a diversity of strategies that have been followed for siting radioactive waste repositories, as well as a range of levels of public acceptance of siting efforts. Although the strategies are not necessarily interchangeable from country to country, certain inferences may be drawn from worldwide siting experience regarding ways to maximize public acceptance. Furthermore, waste management organizations in these countries have placed varying amounts of stock in technical review by outside experts and in a range of communications strategies as means of improving public acceptance. Our survey of worldwide experience also allows some general observations to be made regarding the effectiveness of these efforts. Combining a strategy that elevates public acceptance to part of the overall mission of siting a waste management facility with strategies for appropriate communications and external technical review may be necessary and sufficient for gaining improvements in public acceptance of proposed repository sites

  3. Experience gained in the cryodistillation unit for krypton removal

    International Nuclear Information System (INIS)

    Geens, L.; Collard, G.; Goossens, W.R.A.; Vaesen, P.J.

    1981-08-01

    This unit with a nominal gas throughput of 8.5 g.s -1 has been used to investigate the removal of krypton from reprocessing off-gases under non-radioactive conditions. During the investigation a total operation time of more than 13.000 hours was reached with an average availability factor of 99.36%. The trapping efficiency for krypton was higher than 99.9%. The operation experience acquired indicates some critical aspects for the design of such a unit. The experimental results obtained allow to show the influence of feed pressure and temperature, reflux flow rate and noble gas concentrations on the performance of the unit. (author)

  4. Comparison of Video Head Impulse Test (vHIT) Gains Between Two Commercially Available Devices and by Different Gain Analytical Methods.

    Science.gov (United States)

    Lee, Sang Hun; Yoo, Myung Hoon; Park, Jun Woo; Kang, Byung Chul; Yang, Chan Joo; Kang, Woo Suk; Ahn, Joong Ho; Chung, Jong Woo; Park, Hong Ju

    2018-06-01

    To evaluate whether video head impulse test (vHIT) gains are dependent on the measuring device and method of analysis. Prospective study. vHIT was performed in 25 healthy subjects using two devices simultaneously. vHIT gains were compared between these instruments and using five different methods of comparing position and velocity gains during head movement intervals. The two devices produced different vHIT gain results with the same method of analysis. There were also significant differences in the vHIT gains measured using different analytical methods. The gain analytic method that compares the areas under the velocity curve (AUC) of the head and eye movements during head movements showed lower vHIT gains than a method that compared the peak velocities of the head and eye movements. The former method produced the vHIT gain with the smallest standard deviation among the five procedures tested in this study. vHIT gains differ in normal subjects depending on the device and method of analysis used, suggesting that it is advisable for each device to have its own normal values. Gain calculations that compare the AUC of the head and eye movements during the head movements show the smallest variance.

  5. Experience gained during commissioning and trial operation of Mochovce Nuclear Power Plant

    International Nuclear Information System (INIS)

    GaL, P.; Adamica, T.; Marosik, V.; Rehak, A.

    2000-01-01

    In this paper authors describe the experience gained during commissioning and trial operation of Mochovce NPP (EMO). The first year of EMO operation from the point of view of safety and reliability was successful. Evidently we were challenged with certain problems characteristic to this stage of operation which resulted in automatic reactor shutdown. There were 11 automatic shutdowns in 1998 by action of the quick emergency protection AO-1 and two manual shutdowns by the AO-1 key. In 1999, there were 6 automatic shutdowns by action of the quick emergency protection AO-1. Three of them was connected to the falsely activated binary signal of MCP switch of, in two cases the reason came out from the turbo-generator (TG) cooling water system. Very positive trend in the operation of both units shows the fact that during all commissioning period of the second unit there were only three automatic reactor shutdowns by the signal AO-1. All these actions were done in frame of commissioning tests. All causes which activated the automatic unit shutdowns were found out and rectified, the overall tuning of the cooling water system is on the process now. The solution of this problem is possible only power commissioning, and in the stage of the trial operation had no direct impacts on the nuclear, radiation, or technical safety respectively. In 1998 two events according to the INES scale after second unit commissioning because of two unit links of the cooling water system. The operational events during the commissioning tests, start-up tests, physical commissioning, were ranked the category 1 ('Action of SIS U040 p po <8,34 MPa at the system 2 and 3' and 'Breaching the L and C'). In 1999 only events occurred that were ranked in the category safety insignificant events and lower (category 0, or off the scale respectively). In the frame of the safety culture principles adopted, such as critical attitude, exact and careful approach, and communication, these problems were given the

  6. Rapidity dependence of strangeness enhancement factor at FAIR energies

    International Nuclear Information System (INIS)

    Dey, Kalyan; Bhattacharjee, B.

    2014-01-01

    Strange particles are produced only at the time of collisions and thus expected to carry important information of collision dynamics. Strangeness enhancement is considered to be one of the traditional signatures of formation of Quark Gluon Plasma (QGP). Due to the limitation of the detector acceptance, the past and ongoing heavy ion experiments could measure the strangeness enhancement at midrapidity only. But the future heavy ion experiment CBM at FAIR will have the access to the entire forward rapidity hemisphere and thus the experimental determination of rapidity dependent strangeness enhancement is a possibility. In this work, an attempt has therefore been made to study the rapidity dependent strangeness enhancement at FAIR energies with the help of a string based hadronic model (UrQMD). A sum of 93 million minimum biased UrQMD events have been used for the present analysis

  7. Fast estimation of expected information gains for Bayesian experimental designs based on Laplace approximations

    KAUST Repository

    Long, Quan; Scavino, Marco; Tempone, Raul; Wang, Suojin

    2013-01-01

    Shannon-type expected information gain can be used to evaluate the relevance of a proposed experiment subjected to uncertainty. The estimation of such gain, however, relies on a double-loop integration. Moreover, its numerical integration in multi-dimensional cases, e.g., when using Monte Carlo sampling methods, is therefore computationally too expensive for realistic physical models, especially for those involving the solution of partial differential equations. In this work, we present a new methodology, based on the Laplace approximation for the integration of the posterior probability density function (pdf), to accelerate the estimation of the expected information gains in the model parameters and predictive quantities of interest. We obtain a closed-form approximation of the inner integral and the corresponding dominant error term in the cases where parameters are determined by the experiment, such that only a single-loop integration is needed to carry out the estimation of the expected information gain. To deal with the issue of dimensionality in a complex problem, we use a sparse quadrature for the integration over the prior pdf. We demonstrate the accuracy, efficiency and robustness of the proposed method via several nonlinear numerical examples, including the designs of the scalar parameter in a one-dimensional cubic polynomial function, the design of the same scalar in a modified function with two indistinguishable parameters, the resolution width and measurement time for a blurred single peak spectrum, and the boundary source locations for impedance tomography in a square domain. © 2013 Elsevier B.V.

  8. Fast estimation of expected information gains for Bayesian experimental designs based on Laplace approximations

    KAUST Repository

    Long, Quan

    2013-06-01

    Shannon-type expected information gain can be used to evaluate the relevance of a proposed experiment subjected to uncertainty. The estimation of such gain, however, relies on a double-loop integration. Moreover, its numerical integration in multi-dimensional cases, e.g., when using Monte Carlo sampling methods, is therefore computationally too expensive for realistic physical models, especially for those involving the solution of partial differential equations. In this work, we present a new methodology, based on the Laplace approximation for the integration of the posterior probability density function (pdf), to accelerate the estimation of the expected information gains in the model parameters and predictive quantities of interest. We obtain a closed-form approximation of the inner integral and the corresponding dominant error term in the cases where parameters are determined by the experiment, such that only a single-loop integration is needed to carry out the estimation of the expected information gain. To deal with the issue of dimensionality in a complex problem, we use a sparse quadrature for the integration over the prior pdf. We demonstrate the accuracy, efficiency and robustness of the proposed method via several nonlinear numerical examples, including the designs of the scalar parameter in a one-dimensional cubic polynomial function, the design of the same scalar in a modified function with two indistinguishable parameters, the resolution width and measurement time for a blurred single peak spectrum, and the boundary source locations for impedance tomography in a square domain. © 2013 Elsevier B.V.

  9. Living without Boys: A Retrospective Analysis of the Benefits and Skills Gained at All-Female Camps

    Science.gov (United States)

    Whittington, Anja; Garst, Barry A.; Gagnon, Ryan J.; Baughman, Sarah

    2017-01-01

    The purpose of this study was to investigate the outcomes of all-female camp experiences on women's lives. Using a retrospective approach, this study collected qualitative data from 131 women to examine the benefits of all-female camp experiences, to analyze the skills they gained at camp, and to understand how they apply these skills to their…

  10. Relative Gains, Losses, and Reference Points in Probabilistic Choice in Rats

    Science.gov (United States)

    Marshall, Andrew T.; Kirkpatrick, Kimberly

    2015-01-01

    Theoretical reference points have been proposed to differentiate probabilistic gains from probabilistic losses in humans, but such a phenomenon in non-human animals has yet to be thoroughly elucidated. Three experiments evaluated the effect of reward magnitude on probabilistic choice in rats, seeking to determine reference point use by examining the effect of previous outcome magnitude(s) on subsequent choice behavior. Rats were trained to choose between an outcome that always delivered reward (low-uncertainty choice) and one that probabilistically delivered reward (high-uncertainty). The probability of high-uncertainty outcome receipt and the magnitudes of low-uncertainty and high-uncertainty outcomes were manipulated within and between experiments. Both the low- and high-uncertainty outcomes involved variable reward magnitudes, so that either a smaller or larger magnitude was probabilistically delivered, as well as reward omission following high-uncertainty choices. In Experiments 1 and 2, the between groups factor was the magnitude of the high-uncertainty-smaller (H-S) and high-uncertainty-larger (H-L) outcome, respectively. The H-S magnitude manipulation differentiated the groups, while the H-L magnitude manipulation did not. Experiment 3 showed that manipulating the probability of differential losses as well as the expected value of the low-uncertainty choice produced systematic effects on choice behavior. The results suggest that the reference point for probabilistic gains and losses was the expected value of the low-uncertainty choice. Current theories of probabilistic choice behavior have difficulty accounting for the present results, so an integrated theoretical framework is proposed. Overall, the present results have implications for understanding individual differences and corresponding underlying mechanisms of probabilistic choice behavior. PMID:25658448

  11. Relative gains, losses, and reference points in probabilistic choice in rats.

    Directory of Open Access Journals (Sweden)

    Andrew T Marshall

    Full Text Available Theoretical reference points have been proposed to differentiate probabilistic gains from probabilistic losses in humans, but such a phenomenon in non-human animals has yet to be thoroughly elucidated. Three experiments evaluated the effect of reward magnitude on probabilistic choice in rats, seeking to determine reference point use by examining the effect of previous outcome magnitude(s on subsequent choice behavior. Rats were trained to choose between an outcome that always delivered reward (low-uncertainty choice and one that probabilistically delivered reward (high-uncertainty. The probability of high-uncertainty outcome receipt and the magnitudes of low-uncertainty and high-uncertainty outcomes were manipulated within and between experiments. Both the low- and high-uncertainty outcomes involved variable reward magnitudes, so that either a smaller or larger magnitude was probabilistically delivered, as well as reward omission following high-uncertainty choices. In Experiments 1 and 2, the between groups factor was the magnitude of the high-uncertainty-smaller (H-S and high-uncertainty-larger (H-L outcome, respectively. The H-S magnitude manipulation differentiated the groups, while the H-L magnitude manipulation did not. Experiment 3 showed that manipulating the probability of differential losses as well as the expected value of the low-uncertainty choice produced systematic effects on choice behavior. The results suggest that the reference point for probabilistic gains and losses was the expected value of the low-uncertainty choice. Current theories of probabilistic choice behavior have difficulty accounting for the present results, so an integrated theoretical framework is proposed. Overall, the present results have implications for understanding individual differences and corresponding underlying mechanisms of probabilistic choice behavior.

  12. Optical gain coefficients of silicon: a theoretical study

    Science.gov (United States)

    Tsai, Chin-Yi

    2018-05-01

    A theoretical model is presented and an explicit formula is derived for calculating the optical gain coefficients of indirect band-gap semiconductors. This model is based on the second-order time-dependent perturbation theory of quantum mechanics by incorporating all the eight processes of photon/phonon emission and absorption between the band edges of the conduction and valence bands. Numerical calculation results are given for Si. The calculated absorption coefficients agree well with the existing fitting formula of experiment data with two modes of phonons: optical phonons with energy of 57.73 meV and acoustic phonons with energy of 18.27 meV near (but not exactly at) the zone edge of the X-point in the dispersion relation of phonons. These closely match with existing data of 57.5 meV transverse optical (TO) phonons at the X4-point and 18.6 meV transverse acoustic (TA) phonons at the X3-point of the zone edge. The calculated results show that the material optical gain of Si will overcome free-carrier absorption if the energy separation of quasi-Fermi levels between electrons and holes exceeds 1.15 eV.

  13. Socially-marketed rapid diagnostic tests and ACT in the private sector: ten years of experience in Cambodia

    Directory of Open Access Journals (Sweden)

    Allen Henrietta

    2011-08-01

    Full Text Available Abstract Whilst some populations have recently experienced dramatic declines in malaria, the majority of those most at risk of Plasmodium falciparum malaria still lack access to effective treatment with artemisinin combination therapy (ACT and others are already facing parasites resistant to artemisinins. In this context, there is a crucial need to improve both access to and targeting of ACT through greater availability of good quality ACT and parasitological diagnosis. This is an issue of increasing urgency notably in the private commercial sector, which, in many countries, plays an important role in the provision of malaria treatment. The Affordable Medicines Facility for malaria (AMFm is a recent initiative that aims to increase the provision of affordable ACT in public, private and NGO sectors through a manufacturer-level subsidy. However, to date, there is little documented experience in the programmatic implementation of subsidized ACT in the private sector. Cambodia is in the unique position of having more than 10 years of experience not only in implementing subsidized ACT, but also rapid diagnostic tests (RDT as part of a nationwide social marketing programme. The programme includes behaviour change communication and the training of private providers as well as the sale and distribution of Malarine, the recommended ACT, and Malacheck, the RDT. This paper describes and evaluates this experience by drawing on the results of household and provider surveys conducted since the start of the programme. The available evidence suggests that providers' and consumers' awareness of Malarine increased rapidly, but that of Malacheck much less so. In addition, improvements in ACT and RDT availability and uptake were relatively slow, particularly in more remote areas. The lack of standardization in the survey methods and the gaps in the data highlight the importance of establishing a clear system for monitoring and evaluation for similar initiatives

  14. Rapidity gaps in jet events at D0

    International Nuclear Information System (INIS)

    Abbott, B.; Abolins, M.; Acharya, B.S.

    1997-07-01

    Preliminary results from the D0 experiment on jet production with rapidity gaps in p anti p collisions are presented. A class of dijet events with a forward rapidity gap is observed at center-of-mass energies √s = 1800 GeV and 630 GeV. The number of events with rapidity gaps at both center-of-mass energies is significantly greater than the expectation from multiplicity fluctuations and is consistent with a hard diffractive process. A class of events with two forward gaps and central dijets is also observed at 1800 GeV. This topology is consistent with hard double pomeron exchange

  15. Elevated CO2 stimulates marsh elevation gain, counterbalancing sea-level rise.

    Science.gov (United States)

    Langley, J Adam; McKee, Karen L; Cahoon, Donald R; Cherry, Julia A; Megonigal, J Patrick

    2009-04-14

    Tidal wetlands experiencing increased rates of sea-level rise (SLR) must increase rates of soil elevation gain to avoid permanent conversion to open water. The maximal rate of SLR that these ecosystems can tolerate depends partly on mineral sediment deposition, but the accumulation of organic matter is equally important for many wetlands. Plant productivity drives organic matter dynamics and is sensitive to global change factors, such as rising atmospheric CO(2) concentration. It remains unknown how global change will influence organic mechanisms that determine future tidal wetland viability. Here, we present experimental evidence that plant response to elevated atmospheric [CO(2)] stimulates biogenic mechanisms of elevation gain in a brackish marsh. Elevated CO(2) (ambient + 340 ppm) accelerated soil elevation gain by 3.9 mm yr(-1) in this 2-year field study, an effect mediated by stimulation of below-ground plant productivity. Further, a companion greenhouse experiment revealed that the CO(2) effect was enhanced under salinity and flooding conditions likely to accompany future SLR. Our results indicate that by stimulating biogenic contributions to marsh elevation, increases in the greenhouse gas, CO(2), may paradoxically aid some coastal wetlands in counterbalancing rising seas.

  16. Elevated CO2 stimulates marsh elevation gain, counterbalancing sea-level rise

    Science.gov (United States)

    Langley, J. Adam; McKee, Karen L.; Cahoon, Donald R.; Cherry, Julia A.; Megonigal, J. Patrick

    2009-01-01

    Tidal wetlands experiencing increased rates of sea-level rise (SLR) must increase rates of soil elevation gain to avoid permanent conversion to open water. The maximal rate of SLR that these ecosystems can tolerate depends partly on mineral sediment deposition, but the accumulation of organic matter is equally important for many wetlands. Plant productivity drives organic matter dynamics and is sensitive to global change factors, such as rising atmospheric CO2 concentration. It remains unknown how global change will influence organic mechanisms that determine future tidal wetland viability. Here, we present experimental evidence that plant response to elevated atmospheric [CO2] stimulates biogenic mechanisms of elevation gain in a brackish marsh. Elevated CO2 (ambient + 340 ppm) accelerated soil elevation gain by 3.9 mm yr−1 in this 2-year field study, an effect mediated by stimulation of below-ground plant productivity. Further, a companion greenhouse experiment revealed that the CO2 effect was enhanced under salinity and flooding conditions likely to accompany future SLR. Our results indicate that by stimulating biogenic contributions to marsh elevation, increases in the greenhouse gas, CO2, may paradoxically aid some coastal wetlands in counterbalancing rising seas. PMID:19325121

  17. Association between gestational weight gain and perinatal outcomes in women with chronic hypertension.

    Science.gov (United States)

    Yee, Lynn M; Caughey, Aaron B; Cheng, Yvonne W

    2017-09-01

    over guidelines was associated with similar fetal growth outcomes although with a smaller effect size. In contrast, weight gain less than National Academy of Medicine guidelines was not associated with adverse maternal outcomes but was associated with increased odds of small for gestational age (adjusted odds ratio, 1.31; 95% confidence interval, 1.21-1.52) and decreased odds of large-for-gestational-age status (adjusted odds ratio, 0.86; 95% confidence interval, 0.81-0.92). Analysis of maternal and neonatal outcomes stratified by body mass index demonstrated similar findings. Women with chronic hypertension who gain less weight than National Academy of Medicine guidelines experience increased odds of small-for-gestational-age neonates, whereas excess weight gain ≥20 lb over National Academy of Medicine guidelines is associated with cesarean delivery, eclampsia, 5-minute Apgar <7, neonatal intensive care unit admission, and large-for-gestational-age neonates. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. An S-band high gain relativistic klystron amplifier with high phase stability

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Y. [Institute of Applied Electronics, China Academy of Engineering Physics, Mianyang 621900 (China); Science and Technology on High Power Microwave Laboratory, Mianyang 621900 (China); Li, Z. H.; Xu, Z.; Ma, Q. S. [Institute of Applied Electronics, China Academy of Engineering Physics, Mianyang 621900 (China); Xie, H. Q. [College of Science, Southwestern University of Science and Technology, Mianyang 621010 (China)

    2014-11-15

    For the purpose of coherent high power microwave combining, an S-band high gain relativistic klystron amplifier with high phase stability is presented and studied. By the aid of 3D particle-in-cell code and circuit simulation software, the mechanism of parasitic oscillation in the device is investigated. And the RF lossy material is adopted in the simulation and experiment to suppress the oscillation. The experimental results show that with an input RF power of 10 kW, a microwave pulse with power of 1.8 GW is generated with a gain of 52.6 dB. And the relative phase difference fluctuation between output microwave and input RF signal is less than ±10° in 90 ns.

  19. Estimation of body tissue gain of entire and castrated male pigs at ...

    African Journals Online (AJOL)

    Rates of tissue gain and body composition of 18 entire (E) and 18 castrated (C) male pigs, fed at one of two levels of feeding (high (H) or low (L)), were investigated in a 2x2 factorial experiment. Calorimetric, energy and nitrogen balances were carried out on each animal at 30, 60 and 90 kg live weight. The animals were ...

  20. JINR rapid communications

    International Nuclear Information System (INIS)

    1995-01-01

    The present collection of rapid communications from JINR, Dubna, contains twelve separate reports on an estimation of the possibility of fusion reactions in water molecules, an analysis of pion spectra of the charge-exchange reaction Mg(t, 3 He), the results of simulation of e + e - pair production and detection in the ALICE experiment, the data on the edge effects in multiwire proportional chambers, standard and nonstandard applications of wavelet analysis, the design and study of light readout system for scintillator shower maximum detector for the endcap electromagnetic calorimeter for the STAR experiment at RHIC, a study of multiparticle azimuthal correlations in high energy interactions, coherent multifragmentation of relativistic nuclei, superposition of neutrino eigenstates and neutrino oscillation, simulation results and suggestions for possible design of gaseous shower maximum detector for the endcap electromagnetic calorimeter for the STAR experiment at RHIC, determination of the sizes of the pion emission region in np-interactions at P n =(5.2±0.16)GeV/c using the interference correlation method for identical particles, inelasticity of nucleus-nucleus collisions in the CMS experiment. 65 figs., 19 tabs

  1. Frequency-asymmetric gain profile in a seeded Raman amplifier

    International Nuclear Information System (INIS)

    Repasky, K.S.; Carlsten, J.L.

    1996-01-01

    This paper examines the effect of index guiding on Raman gain. The slowly varying Maxwell wave equation including both the real and imaginary parts of the Raman susceptibility for a seeded Raman amplifier is explored. Using a Gauss-Laguerre mode expansion for the Stokes field, the output Stokes energy is numerically studied as a function of gain and detuning from the Raman resonance. The calculations indicate that the real part of the Raman susceptibility causes the Raman medium to act as a lens when the Stokes seed is detuned from the Raman resonance. This focusing effect leads to higher peak Stokes energy when the Stokes seed is tuned to the blue side of the Raman resonance. Specifically for Raman scattering in H 2 with a pump laser at 532 nm and an input seed near 683 nm, the peak Stokes energy can shift by as much as 300 MHz from the Raman resonance. An experiment which confirms these predictions is also presented. copyright 1996 The American Physical Society

  2. Predictive Variable Gain Iterative Learning Control for PMSM

    Directory of Open Access Journals (Sweden)

    Huimin Xu

    2015-01-01

    Full Text Available A predictive variable gain strategy in iterative learning control (ILC is introduced. Predictive variable gain iterative learning control is constructed to improve the performance of trajectory tracking. A scheme based on predictive variable gain iterative learning control for eliminating undesirable vibrations of PMSM system is proposed. The basic idea is that undesirable vibrations of PMSM system are eliminated from two aspects of iterative domain and time domain. The predictive method is utilized to determine the learning gain in the ILC algorithm. Compression mapping principle is used to prove the convergence of the algorithm. Simulation results demonstrate that the predictive variable gain is superior to constant gain and other variable gains.

  3. How architecture students gain and apply knowledge of sustainable architecture

    DEFF Research Database (Denmark)

    Donovan, Elizabeth; Holder, Anna

    2016-01-01

    understandings of how architects synthesise different types of knowledge while designing, raising questions about the ‘match’ between educational experiences and subsequent behaviours in practice. Taking an example from Denmark, we outline the approach of Aarhus School of Architecture, where sustainability...... teaching is partially integrated within the design studio courses. We compare the institution’s philosophy for sustainability with pedagogical approaches as practiced within the school. An empirical study was made of 2nd year architecture student experiences of a one-month introduction course to ‘Reuse...... to be supported in gaining different types of knowledge (ie. propositional, experiential, applied) through different modes of learning. There are gaps to be bridged in education in order for the sustainability agenda to be fully integrated in architectural practice....

  4. Weight gain - unintentional

    Science.gov (United States)

    ... diabetes Hormone changes or medical problems can also cause unintentional weight gain. This may be due to: Cushing syndrome Underactive thyroid, or low thyroid (hypothyroidism) Polycystic ovary syndrome Menopause Pregnancy Bloating, or swelling ...

  5. Nonlinear gain of a millimetre wave antenna array mounted on a re-entry vehicle

    International Nuclear Information System (INIS)

    Sharma, Ashok Kumar; Kumar, Ashok

    2007-01-01

    A millimetre wave antenna array, mounted on a space vehicle re-entering the Earth's atmosphere, encounters a high density plasma around it. At high antenna power, the millimetre wave field heats the electrons nonuniformly. The electron temperature, T e , follows the antenna pattern, being maximum along the direction of the principal maximum (z-axis) and falling off rapidly across it. The ambipolar plasma diffusion under the pressure gradient force creates a refractive index profile with maximum on the z-axis, leading to self-convergence of the millimetre wave and enhancement in the effective gain of the antenna

  6. CONDITIONS FOR CSR MICROBUNCHING GAIN SUPPRESSION

    Energy Technology Data Exchange (ETDEWEB)

    Tsai, Cheng Ying [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Douglas, David R. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Li, Rui [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Tennant, Christopher D. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); di Mitri, Simone [Elettra–Sincrotrone Trieste, 34149 Basovizza, Trieste, Italy

    2016-05-01

    The coherent synchrotron radiation (CSR) of a high brightness electron beam traversing a series of dipoles, such as transport arcs, may result in phase space degradation. On one hand, the CSR can perturb electron transverse motion in dispersive regions along the beamline, causing emittance growth. On the other hand, the CSR effect on the longitudinal beam dynamics could result in microbunching gain enhancement. For transport arcs, several schemes have been proposed* to suppress the CSR-induced emittance growth. Similarly, several scenarios have been introduced** to suppress CSR-induced microbunching gain, which however mostly aim for linac-based machines. In this paper we try to provide sufficient conditions for suppression of CSR-induced microbunching gain along a transport arc, analogous to*. Several example lattices are presented, with the relevant microbunching analyses carried out by our semi-analytical Vlasov solver***. The simulation results show that lattices satisfying the proposed conditions indeed have microbunching gain suppressed. We expect this analysis can shed light on lattice design approach that could suppress the CSR-induced microbunching gain.

  7. [Rapid karyotyping in the 2nd and 3rd trimester: results and experiences].

    Science.gov (United States)

    Claussen, U; Voigt, H J; Ulmer, R; Beinder, E

    1995-01-01

    Rapid karyotyping in the second and third trimester is an increasing field of collaboration between women's hospitals and human genetics. Techniques available for rapid karyotyping are: 1. Amniocentesis; to obtain amniotic fluid cells for culturing and subsequent chromosome harvesting using the pipette method or the "in situ" technique. The average time between preparation of the amniotic fluid and the verbal notification of the analysed karyotype is 4.65 days for the pipette method and 5.97 days for the "in situ" technique. The major advantages are that amniocentesis can be handled safely by many gynaecologist, and the amniotic fluid samples can be posted easily to cytogenetic units familiar with rapid karyotyping. The main disadvantage is that currently only a few laboratories are able to handle the pipette method or the "in situ" technique for rapid karyotyping. 2. Fetal blood sampling (cordocentesis); and subsequent chromosome analysis on cultivated fetal lymphocytes leading to results within 2 to 4 days. The main advantage of this procedure is the reliability of the results obtained. Fetal blood sampling, however, is restricted to specialists; this may involve scheduling delays. 3. Placental biopsy; with subsequent direct preparation and long term culturing. In comparison to both other techniques this procedure is faster if direct preparation is used. Results can be obtained even on the same day. The main disadvantage, however, is the problem with the reliability of the direct preparation results. They must be confirmed by time-consuming long-term culturing. Data are presented on the likelihood of abnormal ultrasound findings being caused by chromosomal aberrations.(ABSTRACT TRUNCATED AT 250 WORDS)

  8. To break the weight gain-A qualitative study on the experience of school nurses working with overweight children in elementary school.

    Science.gov (United States)

    Thorstensson, Stina; Blomgren, Carola; Sundler, Annelie J; Larsson, Margaretha

    2018-01-01

    To describe the experiences of school nurses working with overweight schoolchildren. School nurses play an important role in health promotion of overweight children. Lifestyle changes and interventions to address being overweight can improve health outcomes and decrease the risk for future health problems. A descriptive and qualitative design with a phenomenological approach was used. Data were gathered through interviews with school nurses working with overweight schoolchildren in Swedish elementary school; the data were subsequently analysed for meanings. Working with overweight children was perceived as demanding and challenging by the school nurses who found conversations on this topic emotionally loaded and complex. In addition, the school nurses needed to be sensitive and supportive to succeed in their support for a healthier everyday life for the schoolchildren. It was stated as important to find ways to break the child's weight gain and to cooperate with the parents in this work. The children's decrease in weight was experienced to be more successful when making small, step-by-step changes together with the child and his or her parents. This study concludes that health talks about being overweight may be a challenge for school nurses. Strategies used to manage and succeed in this work included engaging in motivational conversations, working step by step and cooperating with the child's parents. Furthermore, the nurses experienced that they needed to provide emotional support for overweight children during school time. The school nurses' health promotion needs to focus on how to break weight gain in overweight children. In this work, the nurses' sensitiveness seems pivotal. Further research is needed on school nurses' work with health promotion and support of overweight children concerning how to perform efficient communication and cooperation with the children and their parents. © 2017 John Wiley & Sons Ltd.

  9. A strontium-incorporated nanoporous titanium implant surface for rapid osseointegration

    Science.gov (United States)

    Zhang, Wenjie; Cao, Huiliang; Zhang, Xiaochen; Li, Guanglong; Chang, Qing; Zhao, Jun; Qiao, Yuqin; Ding, Xun; Yang, Guangzheng; Liu, Xuanyong; Jiang, Xinquan

    2016-02-01

    Rapid osseointegration of dental implants will shorten the period of treatment and enhance the comfort of patients. Due to the vital role of angiogenesis played during bone development and regeneration, it might be feasible to promote rapid osseointegration by modifying the implant surface to gain a combined angiogenesis/osteogenesis inducing capacity. In this study, a novel coating (MAO-Sr) with strontium-incorporated nanoporous structures on titanium implants was generated via a new micro-arc oxidation, in an attempt to induce angiogenesis and osteogenesis to enhance rapid osseointegration. In vitro, the nanoporous structure significantly enhanced the initial adhesion of canine BMSCs. More importantly, sustained release of strontium ions also displayed a stronger effect on the BMSCs in facilitating their osteogenic differentiation and promoting the angiogenic growth factor secretion to recruit endothelial cells and promote blood vessel formation. Advanced mechanism analyses indicated that MAPK/Erk and PI3K/Akt signaling pathways were involved in these effects of the MAO-Sr coating. Finally, in the canine dental implantation study, the MAO-Sr coating induced faster bone formation within the initial six weeks and the osseointegration effect was comparable to that of the commercially available ITI implants. These results suggest that the MAO-Sr coating has the potential for future use in dental implants.Rapid osseointegration of dental implants will shorten the period of treatment and enhance the comfort of patients. Due to the vital role of angiogenesis played during bone development and regeneration, it might be feasible to promote rapid osseointegration by modifying the implant surface to gain a combined angiogenesis/osteogenesis inducing capacity. In this study, a novel coating (MAO-Sr) with strontium-incorporated nanoporous structures on titanium implants was generated via a new micro-arc oxidation, in an attempt to induce angiogenesis and osteogenesis to

  10. FEL gain optimisation and spontaneous radiation

    Energy Technology Data Exchange (ETDEWEB)

    Bali, L.M.; Srivastava, A.; Pandya, T.P. [Lucknow Univ. (India)] [and others

    1995-12-31

    Colson have evaluated FEL gains for small deviations from perfect electron beam injection, with radiation of the same polarisation as that of the wiggler fields. We find that for optimum gain the polarisation of the optical field should be the same as that of the spontaneous emission under these conditions. With a helical wiggler the axial oscillations resulting from small departures from perfect electron beam injection lead to injection dependent unequal amplitudes and phases of the spontaneous radiation in the two transverse directions. Viewed along the axis therefore the spontaneous emission is elliptically polarised. The azimuth of the ellipse varies with the difference of phase of the two transverse components of spontaneous emission but the eccentricity remains the same. With planar wigglers the spontaneous emission viewed in the axial direction is linearly polarised, again with an injection dependent azimuth. For optimum coherent gain of a radiation field its polarisation characteristics must be the same as those of the spontaneous radiation with both types of wiggler. Thus, with a helical wiggler and the data reported earlier, an increase of 10% in the FEL gain at the fundamental frequency and of 11% at the fifth harmonic has been calculated in the small gain per pass limit. Larger enhancements in gain may result from more favourable values of input parameters.

  11. JINR rapid communications

    International Nuclear Information System (INIS)

    1995-01-01

    The present collection of rapid communications from JINR, Dubna, contains six separate reports on Monte Carlo simulation of silicon detectors for the ALICE experiment at LHC, a study of single tagged multihadronic γγ* events at an average Q 2 of 90 GeV 2 , epithermal neutron activation analysis of moss, lichen and pine needles in atmospheric deposition monitoring, the theory of neutrino oscillation, coupled quadrupole and monopole vibrations of large amplitude and test of the Ellis-Jaffe sum rule using parametrization of the measured lepton-proton asymmetry. 21 figs., 18 tabs

  12. Gain investigation of Perylene-Red-doped PMMA for stimulated luminescent solar concentrators.

    Science.gov (United States)

    Kaysir, Md Rejvi; Fleming, Simon; Argyros, Alexander

    2018-04-01

    Luminescent solar concentrators (LSCs) utilizing stimulated emission by a seed laser are a promising approach to overcome the limitations of conventional LSCs, with a significant reduction of the photovoltaic material. In our previous work, we demonstrated the principle of a stimulated LSC (s-LSC) and correspondingly developed a model for quantifying the output power of such a system, taking into account different important physical parameters. The model suggested Perylene Red (PR) dye as a potential candidate for s-LSCs. Here, we experimentally investigate the gain of PR-doped polymethyl methacrylate (PMMA) required for s-LSCs using a single pump wavelength (instead of the solar spectrum) as a proof of principle. The results found from the experiment are well matched with the previously developed numerical model except for gain saturation, which occurs at a comparatively small seed laser signal power. To investigate the gain saturation, two approaches were taken: investigating (i) spectral hole burning and (ii) triplet state absorption. Experimental investigation of spectral hole burning with PR dyes showed a small effect on the gain saturation. We developed a general state model considering triplet state absorption of the PR dyes for the second approach. The state model suggests that the PR dyes suffer from significant triplet state absorption loss, which obstructs the normal operation of the PR-based s-LSC system.

  13. Impacts of SST Patterns on Rapid Intensification of Typhoon Megi (2010)

    Science.gov (United States)

    Kanada, Sachie; Tsujino, Satoki; Aiki, Hidenori; Yoshioka, Mayumi K.; Miyazawa, Yasumasa; Tsuboki, Kazuhisa; Takayabu, Izuru

    2017-12-01

    Typhoon Megi (2010), a very intense tropical cyclone with a minimum central pressure of 885 hPa, was characterized by especially rapid intensification. We investigated this intensification process by a simulation experiment using a high-resolution (0.02° × 0.02°) three-dimensional atmosphere-ocean coupled regional model. We also performed a sensitivity experiment with a time-fixed sea surface temperature (SST). The coupled model successfully simulated the minimum central pressure of Typhoon Megi, whereas the fixed SST experiment simulated an excessively low minimum central pressure of 839 hPa. The simulation results also showed a close relationship between the radial SST profiles and the rapid intensification process. Because the warm sea increased near-surface water vapor and hence the convective available potential energy, the high SST in the eye region facilitated tall and intense updrafts inside the radius of maximum wind speed and led to the start of rapid intensification. In contrast, high SST outside this radius induced local secondary updrafts that inhibited rapid intensification even if the mean SST in the core region exceeded 29.0°C. These secondary updrafts moved inward and eventually merged with the primary eyewall updrafts. Then the storm intensified rapidly when the high SST appeared in the eye region. Thus, the changes in the local SST pattern around the storm center strongly affected the rapid intensification process by modulating the radial structure of core convection. Our results also show that the use of a high-resolution three-dimensional atmosphere-ocean coupled model offers promise for improving intensity forecasts of tropical cyclones.

  14. The influence of loss and gain of body mass on ovarian activity in ...

    African Journals Online (AJOL)

    Ovarian activity was studied in 36 dry, Bos taurus cows fed to achieve different rates of body mass loss and gain in a 2 x 2 factorial experiment. Cows were fed hay to supply either 70% (Treatments 1, 2) or 40% (Treatments. 3,4) of their ME requirements for maintenance until they became anoestrus. Following a 90-day ...

  15. 24 CFR 3280.507 - Comfort heat gain.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Comfort heat gain. 3280.507 Section... gain. Information necessary to calculate the home cooling load shall be provided as specified in this part. (a) Transmission heat gains. Homes complying with this section shall meet the minimum heat loss...

  16. Fluorescence-enhanced optical imaging in large tissue volumes using a gain-modulated ICCD camera

    International Nuclear Information System (INIS)

    Godavarty, Anuradha; Eppstein, Margaret J; Zhang, Chaoyang; Theru, Sangeeta; Thompson, Alan B; Gurfinkel, Michael; Sevick-Muraca, Eva M

    2003-01-01

    A novel image-intensified charge-coupled device (ICCD) imaging system has been developed to perform 3D fluorescence tomographic imaging in the frequency-domain using near-infrared contrast agents. The imager is unique since it (i) employs a large tissue-mimicking phantom, which is shaped and sized to resemble a female breast and part of the extended chest-wall region, and (ii) enables rapid data acquisition in the frequency-domain by using a gain-modulated ICCD camera. Diffusion model predictions are compared to experimental measurements using two different referencing schemes under two different experimental conditions of perfect and imperfect uptake of fluorescent agent into a target. From these experimental measurements, three-dimensional images of fluorescent absorption were reconstructed using a computationally efficient variant of the approximate extended Kalman filter algorithm. The current work represents the first time that 3D fluorescence-enhanced optical tomographic reconstructions have been achieved from experimental measurements of the time-dependent light propagation on a clinically relevant breast-shaped tissue phantom using a gain-modulated ICCD camera

  17. Portable Diagnostics and Rapid Germination

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, Zachary Spencer [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-12-01

    In the Bioenergy and Defense Department of Sandia National Laboratories, characterization of the BaDx (Bacillus anthracis diagnostic cartridge) was performed and rapid germination chemistry was investigated. BaDx was tested with complex sample matrixes inoculated with Bacillus anthracis, and the trials proved that BaDx will detect Bacillus anthracis in a variety of the medium, such as dirt, serum, blood, milk, and horse fluids. The dimensions of the device were altered to accommodate an E. coli or Listeria lateral flow immunoassay, and using a laser printer, BaDx devices were manufactured to identify E. coli and Listeria. Initial testing with E. coli versions of BaDx indicate that the device will be viable as a portable diagnostic cartridge. The device would be more effective with faster bacteria germination; hence studies were performed the use of rapid germination chemistry. Trials with calcium dipicolinic acid displayed increased cell germination, as shown by control studies using a microplate reader. Upon lyophilization the rapid germination chemistry failed to change growth patterns, indicating that the calcium dipicolinic acid was not solubilized under the conditions tested. Although incompatible with the portable diagnostic device, the experiments proved that the rapid germination chemistry was effective in increasing cell germination.

  18. Spontaneous indices are inconsistent with arterial baroreflex gain.

    Science.gov (United States)

    Lipman, Ruth D; Salisbury, Julie K; Taylor, J Andrew

    2003-10-01

    Spontaneously occurring, parallel fluctuations in arterial pressure and heart period are frequently used as indices of baroreflex function. Despite the convenience of spontaneous indices, their relation to the arterial baroreflex remains unclear. Therefore, in 97 volunteers, we derived 5 proposed indices (sequence method, alpha-index, transfer function, low-frequency transfer function, and impulse response function), compared them with arterial baroreflex gain (by the modified Oxford pharmacologic technique), and examined their relation to carotid distensibility and respiratory sinus arrhythmia. The subjects comprised men and women (n=41) aged 25 to 86 years, 30% of whom had established coronary artery disease. Generally, the indices were correlated with each other (except alpha-index and low-frequency transfer function) and with baroreflex gain. However, the Bland-Altman method demonstrated that the spontaneous indices had limits of agreement as large as the baroreflex gain itself. Even in individuals within the lowest tertile of baroreflex gain for whom baroreflex gain appears to be the most clinically relevant, spontaneous indices failed to relate to baroreflex gain. In fact, for these individuals, there was no correlation between any index and baroreflex gain. Forward stepwise linear regression showed that all spontaneous indices and baroreflex gain were related to respiratory sinus arrhythmia, but only baroreflex gain was related to carotid distensibility. Therefore, these data suggest that spontaneous indices are inadequate estimates of gain and are inconsistent with arterial baroreflex function.

  19. Review of High Gain FELs

    International Nuclear Information System (INIS)

    Shintake, Tsumoru

    2007-01-01

    For understanding on basic radiation mechanism of the high-gain FEL based on SASE, the author presents electron-crystal interpretation of FEL radiation. In the electron-crystal, electrons are localized at regularly spaced multi-layers, which represents micro-bunching, whose spacing is equal to the radiation wavelength, and the multi-layers are perpendicular to beam axis, thus, diffracted wave creates Bragg's spots in forward and backward directions. Due to the Doppler's effect, frequency of the back-scattered wave is up-converted, generates forwardly focused X-ray. The Bragg's effect contributes focusing the X-ray beam into a spot, thus peak power becomes extremely higher by factor of typically 107. This is the FEL radiation. As well known, the total numbers of scattered photons in Bragg's spots is equal to the total elastic scattering photons from the atoms contained in the crystal. Therefore, total power in the FEL laser is same as the spontaneous radiation power from the undulator for the same beam parameter. The FEL radiation phenomenon is simple interference effect. In today's presentations, we use the laser pointer, and we frequently experience difficulty in pointing precisely or steadily in one place on the screen, since the laser spot is very small and does not spread. Exactly same to this, X-ray FEL is a highly focused beam, and pointing stability dominates productivity of experiment, thus we need special care on beam stability from linear accelerator

  20. Insulin detemir attenuates food intake, body weight gain and fat mass gain in diet-induced obese Sprague-Dawley rats.

    Science.gov (United States)

    Rojas, J M; Printz, R L; Niswender, K D

    2011-07-04

    Initiation and intensification of insulin therapy commonly causes weight gain, a barrier to therapy. A contrasting body of evidence indicates that insulin functions as an adiposity negative feedback signal and reduces food intake, weight gain and adiposity via action in the central nervous system. Basal insulin analogs, detemir (Det) and glargine (Glar), have been associated with less hypoglycemia compared with neutral protamine hagedorn insulin, and Det with less weight gain, especially in patients with higher body mass index (BMI). We sought to determine whether insulin therapy per se causes body weight and fat mass gain when delivered via a clinically relevant subcutaneous (SC) route in the absence of hypoglycemia and glycosuria in non-diabetic lean and diet-induced obese rats. Rats were exposed to either a low-fat diet (LFD; 13.5% fat) or high-fat diet (HFD; 60% fat), and received Det (0.5 U kg(-1)), Glar (0.2 U kg(-1)) or vehicle (Veh) SC once daily for 4 weeks. These dosages of insulin were equipotent in rats with respect to blood-glucose concentration and did not induce hypoglycemia. As predicted by current models of energy homeostasis, neither insulin Det nor Glar therapy affected food intake and weight gain in LFD rats. Det treatment significantly attenuated food intake, body weight gain and fat mass gain relative to the Glar and Veh in high-fat fed animals, mirroring observations in humans. That neither insulin group gained excess weight, suggests weight gain with SC basal insulin therapy may not be inevitable. Our data further suggest that Det possesses a unique property to attenuate the development of obesity associated with a HFD.

  1. The effect of experience on the hunting success of newly emerged spiderlings.

    Science.gov (United States)

    Morse

    2000-12-01

    Initial interactions with prey may affect a predator's subsequent foraging success. With experience, second-instar Misumena vatia spiderlings (Thomisidae) that had recently emerged from their egg sacs oriented faster to fruit flies (Drosophila melanogaster) than näive individuals. Orientation time of these spiderlings decreased rapidly for the first two to three runs (every third day) in a simple laboratory setting, and then remained low and relatively constant. Time to capture a fly also declined initially, but subsequently became extremely variable, increasing prior to moult. Increase in capture time and the failure to capture prey appeared associated with impending moult, rather than satiation. Spiderlings oriented to prey more rapidly at the beginning of the third instar than at the start of the second instar, suggesting that experience still enhanced performance after a moult cycle. Overall capture times at the beginning of the third instar decreased from those at the end of the second instar, but did not differ significantly from the beginning of the second instar, although spiderlings gaining the most biomass had the shortest mean capture times. In a second experiment, time to orient and time to capture prey did not differ in näive, second-instar siblings run 1 and 3 days after emergence from their egg sacs. However, 3-day individuals that had captured prey each day (confiscated before they could feed) oriented faster than näive 3-day-old siblings, but did not differ in the time taken to capture prey. Experience, rather than age or energetic condition, best explains these changes in performance. Copyright 2000 The Association for the Study of Animal Behaviour.

  2. The effect of holiday weight gain on body weight.

    Science.gov (United States)

    Schoeller, Dale A

    2014-07-01

    The topic of holiday weight gain has been a frequent subject of the lay media; however, scientific interest has only been recent. Multiple studies in Western societies have reported average weight gains among adults during the period between mid-November and mid-January that were about 0.5 kg. The range in individual weight changes was large, however, and the already overweight and obese gain more weight than those who are healthy weight. When the average gain across the year was also measured, the holiday weight was the major contributor to annual excess weight gain. Efforts patterned to increase awareness to energy balance and body weight have been shown to be successful at reducing such gain. An exception to holiday weight gain being a major contributor to annual excess gain has been children, in whom summer weight gains have been observed to be the major contributor to average excess weight gain. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. Pocket pathologist: A mobile application for rapid diagnostic surgical pathology consultation

    Directory of Open Access Journals (Sweden)

    Douglas J Hartman

    2014-01-01

    Full Text Available Introduction: Telepathology allows the digital transmission of images for rapid access to pathology experts. Recent technologic advances in smartphones have allowed them to be used to acquire and transmit digital images of the glass slide, representing cost savings and efficiency gains over traditional forms of telepathology. We report our experience with developing an iPhone application (App - Pocket Pathologist to facilitate rapid diagnostic pathology teleconsultation utilizing a smartphone. Materials and Methods: A secure, web-based portal (http://pathconsult.upmc.com/ was created to facilitate remote transmission of digital images for teleconsultation. The App augments functionality of the web-based portal and allows the user to quickly and easily upload digital images for teleconsultation. Image quality of smartphone cameras was evaluated by capturing images using different adapters that directly attach phones to a microscope ocular lens. Results: The App was launched in August 2013. The App facilitated easy submission of cases for teleconsultation by limiting the number of data entry fields for users and enabling uploading of images from their smartphone′s gallery wirelessly. Smartphone cameras properly attached to a microscope create static digital images of similar quality to a commercial digital microscope camera. Conclusion: Smartphones have great potential to support telepathology because they are portable, provide ubiquitous internet connectivity, contain excellent digital cameras, and can be easily attached to a microscope. The Pocket Pathologist App represents a significant reduction in the cost of creating digital images and submitting them for teleconsultation. The iPhone App provides an easy solution for global users to submit digital pathology images to pathology experts for consultation.

  4. Self-administered nicotine differentially impacts body weight gain in obesity-prone and obesity-resistant rats.

    Science.gov (United States)

    Rupprecht, Laura E; Smith, Tracy T; Donny, Eric C; Sved, Alan F

    2017-07-01

    Obesity and tobacco smoking represent the largest challenges to public health, but the causal relationship between nicotine and obesity is poorly understood. Nicotine suppresses body weight gain, a factor impacting smoking initiation and the failure to quit, particularly among obese smokers. The impact of nicotine on body weight regulation in obesity-prone and obesity-resistant populations consuming densely caloric diets is unknown. In the current experiment, body weight gain of adult male rats maintained on a high energy diet (31.8% kcal from fat) distributed into obesity-prone (OP), obesity-resistant (OR) and an intermediate group, which was placed on standard rodent chow (Chow). These rats were surgically implanted with intravenous catheters and allowed to self-administer nicotine (0 or 60μg/kg/infusion, a standard self-administration dose) in 1-h sessions for 20 consecutive days. Self-administered nicotine significantly suppressed body weight gain but not food intake in OP and Chow rats. Self-administered nicotine had no effect on body weight gain in OR rats. These data suggest that: 1) OR rats are also resistant to nicotine-induced suppression of body weight gain; and 2) nicotine may reduce levels of obesity in a subset of smokers prone to obesity. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Personality type influence the gestational weight gain.

    Science.gov (United States)

    Franik, Grzegorz; Lipka, Nela; Kopyto, Katarzyna; Kopocińska, Joanna; Owczarek, Aleksander; Sikora, Jerzy; Madej, Paweł; Chudek, Jerzy; Olszanecka-Glinianowicz, Magdalena

    2017-08-01

    Pregnancy is frequently followed by the development of obesity. Aside from psychological factors, hormonal changes influence weight gain in pregnant women. We attempted to assess the potential association between personality type and the extent of gestational weight gain. The study group involved 773 women after term delivery (age 26.3 ± 3.9 years, body mass before pregnancy 61.2 ± 11.1 kg). Weight gain during pregnancy was calculated by using self-reported body mass prior to and during the 38th week of pregnancy. Personality type was assessed using the Polish version of the Framingham Type A Behavior Patterns Questionnaire (adapted by Juczynski). Two hundred forty-six (31.8%) study subjects represented type A personalities, 272 (35.2%) type B and 255 (33.0%) an indirect type. Gestational weight gain was related to the behavior patterns questionnaire score and age. In women gain was higher than in women with type B behavior of the same age. In women >30, the gestational weight gain was larger for type B personalities. Type A personality and increased urgency in younger pregnant women increases the risk of developing obesity during pregnancy in women below 30 years old. A higher level of competitiveness demonstrates a risk factor of excessive weight gain during pregnancy regardless of age.

  6. Spatially resolved x-ray laser spectra and demonstration of gain in nickel-like systems

    Energy Technology Data Exchange (ETDEWEB)

    Whelan, D.A.; Keane, C.J.; MacGowan, B.J.; Matthews, D.L.; Trebes, J.E.; Eckart, M.J.

    1987-09-25

    A recent series of experiments have provided spatially resolved near field images of several candidate x-ray lasing transition in neon-like, nickel-like, and hydrogen-like ions from laser-produced plasmas. From these time-gated, spatially, and spectrally resolved measurements the source size for the J = 0 - 1 and the J = 2 - 1 transitions in Ne-like selenium have been determined. Source regions as small as 50 ..mu..m have been observed on transitions with gain-length products >9. In addition, we have obtained the first experimental evidence for the amplification of spontaneous emission in the nickel-like ions of europium and ytterbium. Gains of order 1 cm/sup -1/ and gain-length products of up to 3.8 are observed on the J = 0 - 1, 4d-4p transitions in Eu + 35 at 65.26 and 71.00 A. Analogous transitions in Yb = +42 have been identified and some evidence for ASE has been observed. 7 refs., 11 figs.

  7. Spatially resolved X-ray laser spectra and demonstration of gain in nickel-like systems

    International Nuclear Information System (INIS)

    Whelan, D.A.; Keane, C.J.; MacGowan, B.J.; Matthews, D.L.; Trebes, J.E.; Eckart, M.J.

    1987-01-01

    A recent series of experiments have provided spatially resolved near field images of several candidate x-ray lasing transition in neon-like, nickel-like, and hydrogen-like ions from laser-produced plasmas. From these time-gated, spatially, and spectrally resolved measurements the source size for the J=0-1 and the J=2-1 transitions in Ne-like selenium have been determined. Source regions as small as 50 μm have been observed on transitions with gain-length products >9. In addition, the authors have obtained the first experimental evidence for the amplification of spontaneous emission in the nickel-like ions of europium and ytterbium. Gains of order 1 cm/sup -1/ and gain-length products of up to 3.8 are observed on the J=0-1,4d-4p transitions in Eu/sup +35/ at 65.83 and 71.00A. Analogous transitions in Yb/sup +42/ have been identified and some evidence for ASE has been observed

  8. IQ Gains in Argentina between 1964 and 1998

    Science.gov (United States)

    Flynn, James R.; Rossi-Case, Lilia

    2012-01-01

    The literature on IQ gains in Latin America is sparse. We estimate gains on Raven's Progressive Matrices in the city of La Plata (Argentina) between 1964 and 1998. The gains are robust at the top of the curve as well as at the bottom. Therefore, they are contrary to the hypothesis that nutrition played a major role in recent Argentine IQ gains.…

  9. Loss restlessness and gain calmness: durable effects of losses and gains on choice switching.

    Science.gov (United States)

    Yechiam, Eldad; Zahavi, Gal; Arditi, Eli

    2015-08-01

    While the traditional conceptualization of the effect of losses focuses on bias in the subjective weight of losses compared with respective gains, some accounts suggest more global task-related effects of losses. Based on a recent attentional theory, we predicted a positive after-effect of losses on choice switching in later tasks. In two experimental studies, we found increased choice switching rates in tasks with losses compared to tasks with no losses. Additionally, this heightened shifting behavior was maintained in subsequent tasks that do not include losses, a phenomenon we refer to as "loss restlessness." Conversely, gains were found to have an opposite "calming" effect on choice switching. Surprisingly, the loss restlessness phenomenon was observed following an all-losses payoff regime but not after a task with symmetric mixed gains and losses. This suggests that the unresolved mental account following an all-losses regime increases search behavior. Potential implications to macro level phenomena, such as the leverage effect, are discussed.

  10. Rapid Structural Design Change Evaluation with AN Experiment Based FEM

    Science.gov (United States)

    Chu, C.-H.; Trethewey, M. W.

    1998-04-01

    The work in this paper proposes a dynamic structural design model that can be developed in a rapid fashion. The approach endeavours to produce a simplified FEM developed in conjunction with an experimental modal database. The FEM is formulated directly from the geometry and connectivity used in an experimental modal test using beam/frame elements. The model sacrifices fine detail for a rapid development time. The FEM is updated at the element level so the dynamic response replicates the experimental results closely. The physical attributes of the model are retained, making it well suited to evaluate the effect of potential design changes. The capabilities are evaluated in a series of computational and laboratory tests. First, a study is performed with a simulated cantilever beam with a variable mass and stiffness distribution. The modal characteristics serve as the updating target with random noise added to simulate experimental uncertainty. A uniformly distributed FEM is developed and updated. The results show excellent results, all natural frequencies are within 0·001% with MAC values above 0·99. Next, the method is applied to predict the dynamic changes of a hardware portal frame structure for a radical design change. Natural frequency predictions from the original FEM differ by as much as almost 18% with reasonable MAC values. The results predicted from the updated model produce excellent results when compared to the actual hardware changes, the first five modal natural frequency difference is around 5% and the corresponding mode shapes producing MAC values above 0·98.

  11. Central gain control in tinnitus and hyperacusis

    Directory of Open Access Journals (Sweden)

    Benjamin D Auerbach

    2014-10-01

    Full Text Available Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural activity transmitted from the cochlea to the central auditory system. Despite a reduced cochlear output, neural activity from more central auditory structures is paradoxically enhanced at suprathreshold intensities. This compensatory increase in the central auditory activity in response to the loss of sensory input is referred to as central gain enhancement. Enhanced central gain is hypothesized to be a potential mechanism that gives rise to hyperacusis and tinnitus, two debilitating auditory perceptual disorders that afflict millions of individuals. This review will examine the evidence for gain enhancement in the central auditory system in response to cochlear damage. Further, it will address the potential cellular and molecular mechanisms underlying this enhancement and discuss the contribution of central gain enhancement to tinnitus and hyperacusis. Current evidence suggests that multiple mechanisms with distinct temporal and spectral profiles are likely to contribute to central gain enhancement. Dissecting the contributions of these different mechanisms at different levels of the central auditory system is essential for elucidating the role of central gain enhancement in tinnitus and hyperacusis and, most importantly, the development of novel treatments for these disorders.

  12. Central Gain Control in Tinnitus and Hyperacusis

    Science.gov (United States)

    Auerbach, Benjamin D.; Rodrigues, Paulo V.; Salvi, Richard J.

    2014-01-01

    Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural activity transmitted from the cochlea to the central auditory system. Despite a reduced cochlear output, neural activity from more central auditory structures is paradoxically enhanced at suprathreshold intensities. This compensatory increase in the central auditory activity in response to the loss of sensory input is referred to as central gain enhancement. Enhanced central gain is hypothesized to be a potential mechanism that gives rise to hyperacusis and tinnitus, two debilitating auditory perceptual disorders that afflict millions of individuals. This review will examine the evidence for gain enhancement in the central auditory system in response to cochlear damage. Further, it will address the potential cellular and molecular mechanisms underlying this enhancement and discuss the contribution of central gain enhancement to tinnitus and hyperacusis. Current evidence suggests that multiple mechanisms with distinct temporal and spectral profiles are likely to contribute to central gain enhancement. Dissecting the contributions of these different mechanisms at different levels of the central auditory system is essential for elucidating the role of central gain enhancement in tinnitus and hyperacusis and, most importantly, the development of novel treatments for these disorders. PMID:25386157

  13. Pregnant women's perceptions of gestational weight gain: A systematic review and meta-synthesis of qualitative research.

    Science.gov (United States)

    Vanstone, Meredith; Kandasamy, Sujane; Giacomini, Mita; DeJean, Deirdre; McDonald, Sarah D

    2017-10-01

    Excess gestational weight gain has numerous negative health outcomes for women and children, including high blood pressure, diabetes, and cesarean section (maternal) and high birth weight, trauma at birth, and asphyxia (infants). Excess weight gain in pregnancy is associated with a higher risk of long-term obesity in both mothers and children. Despite a concerted public health effort, the proportion of pregnant women gaining weight in excess of national guidelines continues to increase. To understand this phenomenon and offer suggestions for improving interventions, we conducted a systematic review of qualitative research on pregnant women's perceptions and experiences of weight gain in pregnancy. We used the methodology of qualitative meta-synthesis to analyze 42 empirical qualitative research studies conducted in high-income countries and published between 2005 and 2015. With this synthesis, we provide an account of the underlying factors and circumstances (barriers, facilitators, and motivators) that pregnant women identify as important for appropriate weight gain. We also offer a description of the strategies identified by pregnant women as acceptable and appropriate ways to promote healthy weight gain. Through our integrative analysis, we identify women's common perception on the struggle to enact health behaviors and physical, social, and environmental factors outside of their control. Effective and sensitive interventions to encourage healthy weight gain in pregnancy must consider the social environment in which decisions about weight take place. © 2016 John Wiley & Sons Ltd.

  14. Patient–Provider Communication and Counseling about Gestational Weight Gain and Physical Activity: A Qualitative Study of the Perceptions and Experiences of Latinas Pregnant with their First Child

    Directory of Open Access Journals (Sweden)

    Ana Cristina Lindsay

    2017-11-01

    Full Text Available Latina women in the United States (U.S. are disproportionately affected by obesity and are more likely to begin pregnancy overweight and gain excessive weight during pregnancy. The prenatal care period represents a window of opportunity for women to access the healthcare system and receive preventive services, education, nutritional support, and other social services to improve pregnancy outcomes. Excessive gestational weight gain (GWG has numerous negative short- and long-term consequences for both the mother and newborn. We explored nulliparous Latina women’s perceptions about their experiences communicating with their primary healthcare provider about GWG and physical activity (PA to identify possible intervention targets using in-depth, semi-structured interviews. Bilingual, trained research staff conducted 23 interviews with first-time pregnant Latinas between 22 and 36 weeks of gestation. Interviews were transcribed verbatim and analyzed using content analysis. Salient text passages were extracted, shortened, coded, and grouped into categories. Women, including those who self-identified as being overweight or obese prior to pregnancy, reported receiving limited or no advice from their healthcare providers about GWG or PA. Additionally, analysis revealed that although participants value information received from the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC program counselors, they would like to receive more information from their primary healthcare providers about adequate GWG. Furthermore, study findings indicate that some participants received conflicting information regarding PA during pregnancy. Study findings suggest the need for increased integration of communication and counseling about GWG and PA into prenatal care services to promote healthy weight gain and PA among low-income Latina women.

  15. Spin-Label CW Microwave Power Saturation and Rapid Passage with Triangular Non-Adiabatic Rapid Sweep (NARS) and Adiabatic Rapid Passage (ARP) EPR Spectroscopy

    Science.gov (United States)

    Kittell, Aaron W.; Hyde, James S.

    2015-01-01

    Non-adiabatic rapid passage (NARS) electron paramagnetic resonance (EPR) spectroscopy was introduced by Kittell, A.W., Camenisch, T.G., Ratke, J.J. Sidabras, J.W., Hyde, J.S., 2011 as a general purpose technique to collect the pure absorption response. The technique has been used to improve sensitivity relative to sinusoidal magnetic field modulation, increase the range of inter-spin distances that can be measured under near physiological conditions, and enhance spectral resolution in copper (II) spectra. In the present work, the method is extended to CW microwave power saturation of spin-labeled T4 Lysozyme (T4L). As in the cited papers, rapid triangular sweep of the polarizing magnetic field was superimposed on slow sweep across the spectrum. Adiabatic rapid passage (ARP) effects were encountered in samples undergoing very slow rotational diffusion as the triangular magnetic field sweep rate was increased. The paper reports results of variation of experimental parameters at the interface of adiabatic and non-adiabatic rapid sweep conditions. Comparison of the forward (up) and reverse (down) triangular sweeps is shown to be a good indicator of the presence of rapid passage effects. Spectral turning points can be distinguished from spectral regions between turning points in two ways: differential microwave power saturation and differential passage effects. Oxygen accessibility data are shown under NARS conditions that appear similar to conventional field modulation data. However, the sensitivity is much higher, permitting, in principle, experiments at substantially lower protein concentrations. Spectral displays were obtained that appear sensitive to rotational diffusion in the range of rotational correlation times of 10−3 to 10−7 s in a manner that is analogous to saturation transfer spectroscopy. PMID:25917132

  16. Nocturnal Anxiety in a Youth with Rapid-onset Obesity, Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD).

    Science.gov (United States)

    Grudnikoff, Eugene; Foley, Carmel; Poole, Claudette; Theodosiadis, Eva

    2013-08-01

    Behavioral and psychiatric disorders are common in youth with rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD). We outline a rational approach to psychiatric treatment of a patient with a complex medical condition. We report the course of symptoms in a teen with ROHHAD, the inpatient treatment, and review current evidence for use of psychopharmacologic agents in youth with sleep and anxiety disturbances. A 14-year-old female began rapidly gaining weight as a preschooler, developed hormonal imbalance, and mixed sleep apnea. Consultation was requested after a month of ROHHAD exacerbation, with severe anxiety, insomnia, and auditory hallucinations. Olanzapine and citalopram were helpful in controlling the symptoms. Following discharge, the patient gained weight and olanzapine was discontinued. Lorazepam was started in coordination with pulmonary service. Relevant pharmacologic considerations included risk of respiratory suppression, history of paradoxical reaction to hypnotics, hepatic isoenzyme interactions and side effects of antipsychotics. Core symptoms of ROHHAD may precipitate psychiatric disorders. A systematic evidence-based approach to psychopharmacology is necessary in the setting of psychiatric consultation.

  17. Validation of Tilt Gain under Realistic Path Loss Model and Network Scenario

    DEFF Research Database (Denmark)

    Nguyen, Huan Cong; Rodriguez, Ignacio; Sørensen, Troels Bundgaard

    2013-01-01

    Despite being a simple and commonly-applied radio optimization technique, the impact on practical network performance from base station antenna downtilt is not well understood. Most published studies based on empirical path loss models report tilt angles and performance gains that are far higher...... than practical experience suggests. We motivate in this paper, based on a practical LTE scenario, that the discrepancy partly lies in the path loss model, and shows that a more detailed semi-deterministic model leads to both lower gains in terms of SINR, outage probability and downlink throughput...... settings, including the use of electrical and/or mechanical antenna downtilt, and therefore it is possible to find multiple optimum tilt profiles in a practical case. A broader implication of this study is that care must be taken when using the 3GPP model to evaluate advanced adaptive antenna techniques...

  18. Nurses' perception of the strategies to gaining professional power: A qualitative study.

    Science.gov (United States)

    Sepasi, Rana Rezai; Borhani, Fariba; Abbaszadeh, Abbas

    2017-07-01

    Power in nursing is a broad concept that has a determining effect on the achievement of professional goals. Gaining power is essential for promoting the roles of nurses, improving their professional image and the consistent improvement of healthcare systems. This study was conducted to identify and clarify strategies for gaining power in the nursing profession through the experiences of Iranian nurses. The present qualitative grounded theory study was conducted on fifteen participants selected through purposive sampling. Data were collected through individual, in-depth, semi-structured interviews. The data obtained were analyzed using the guidelines provided by Corbin and Strauss, (2008 edition). This study was carried out in Qazvin city of Iran and lasted fourteen months (2015-2016). The analysis of the data were classified under the main theme of gaining human-professional power based on individual and organizational capacities, divided into four main categories, including respecting human values and ethical principles (with two subcategories, keeping the human symbols of power and commitment to moral obligations of power), promoting professional interactions (with two subcategories, paying attention to intraprofessional communication and paying attention to interprofessional communication), attempting professional endurance (with two subcategories, raising self-confidence and having professional commitment), and valuing potential capacities (with two subcategories, regard for individual capacities and regard for organizational capacities). The findings obtained suggest that success in gaining power in nursing, requires a cumulative focus on human, ethical, professional, individual and organizational capacities.

  19. Measured stimulated Raman gain in methane

    International Nuclear Information System (INIS)

    Lopert, R.B.

    1983-01-01

    This report is about the stimulated Raman effect in methane due to the nu 1 vibration. For various gas pressures between 150 torr and 30 atm, the Raman lineshape function was both experimentally measured and synthesized using a computer model. The stimulated Raman gain was measured by sending a pump laser beam provided by an argon-ion laser and a weak probe beam provided by a tunable dye laser through a cell of methane gas. The stimulated Raman effect caused some of the energy from the pump beam to be transferred to the probe beam. The intensity of the pump beam was low so the gain of the probe beam was on the order of parts per million. A two detector arrangement and a differential amplifier system that had a feedback loop to balance the detectors was constructed to measure the small gains. A detailed description of this detection system that was able to measure gains as small as 0.2 parts per million is provided

  20. Rapid Cycling Genomic Selection in a Multiparental Tropical Maize Population.

    Science.gov (United States)

    Zhang, Xuecai; Pérez-Rodríguez, Paulino; Burgueño, Juan; Olsen, Michael; Buckler, Edward; Atlin, Gary; Prasanna, Boddupalli M; Vargas, Mateo; San Vicente, Félix; Crossa, José

    2017-07-05

    Genomic selection (GS) increases genetic gain by reducing the length of the selection cycle, as has been exemplified in maize using rapid cycling recombination of biparental populations. However, no results of GS applied to maize multi-parental populations have been reported so far. This study is the first to show realized genetic gains of rapid cycling genomic selection (RCGS) for four recombination cycles in a multi-parental tropical maize population. Eighteen elite tropical maize lines were intercrossed twice, and self-pollinated once, to form the cycle 0 (C 0 ) training population. A total of 1000 ear-to-row C 0 families was genotyped with 955,690 genotyping-by-sequencing SNP markers; their testcrosses were phenotyped at four optimal locations in Mexico to form the training population. Individuals from families with the best plant types, maturity, and grain yield were selected and intermated to form RCGS cycle 1 (C 1 ). Predictions of the genotyped individuals forming cycle C 1 were made, and the best predicted grain yielders were selected as parents of C 2 ; this was repeated for more cycles (C 2 , C 3 , and C 4 ), thereby achieving two cycles per year. Multi-environment trials of individuals from populations C 0, C 1 , C 2 , C 3 , and C 4 , together with four benchmark checks were evaluated at two locations in Mexico. Results indicated that realized grain yield from C 1 to C 4 reached 0.225 ton ha -1 per cycle, which is equivalent to 0.100 ton ha -1  yr -1 over a 4.5-yr breeding period from the initial cross to the last cycle. Compared with the original 18 parents used to form cycle 0 (C 0 ), genetic diversity narrowed only slightly during the last GS cycles (C 3 and C 4 ). Results indicate that, in tropical maize multi-parental breeding populations, RCGS can be an effective breeding strategy for simultaneously conserving genetic diversity and achieving high genetic gains in a short period of time. Copyright © 2017 Zhang et al.

  1. Gain-loss frequency and final outcome in the Soochow Gambling Task: A Reassessment

    Directory of Open Access Journals (Sweden)

    Lin Ching-Hung

    2009-11-01

    Full Text Available Abstract Background Behavioral decision making literature suggests that decision makers are guided less by final outcome than by immediate gain-loss. However, studies of the Iowa Gambling Task (IGT under dynamic and uncertain conditions reveal very different conclusions about the role of final outcome. Another research group designed a similar yet simpler game, the Soochow Gambling Task (SGT, which demonstrated that, in dynamic decision making, the effect of gain-loss frequency is more powerful than that of final outcome. Further study is needed to determine the precise effect of final outcome on decision makers. This experiment developed two modified SGTs to explore the effect of final outcome under the same gain-loss frequency context. Methods Each version of the SGT was performed by twenty-four undergraduate Soochow University students. A large-value (± $200, ± $550 and ± $1050 and a small-value (± $100, ± $150 and ± $650 contrast of SGT were conducted to investigate the final outcome effect. The computerized SGT was launched to record and analyze the choices of the participants. Results The results of both SGT versions consistently showed that the preferred decks A and B to decks C and D. Analysis of learning curves also indicated that, throughout the game, final outcome had a minimal effect on the choices of decision makers. Conclusion Experimental results indicated that, in both the frequent-gain context and the frequent-loss context, final outcome has little effect on decision makers. Most decision makers are guided by gain-loss frequency but not by final outcome.

  2. The Use of Rapid Review Methods for the U.S. Preventive Services Task Force.

    Science.gov (United States)

    Patnode, Carrie D; Eder, Michelle L; Walsh, Emily S; Viswanathan, Meera; Lin, Jennifer S

    2018-01-01

    Rapid review products are intended to synthesize available evidence in a timely fashion while still meeting the needs of healthcare decision makers. Various methods and products have been applied for rapid evidence syntheses, but no single approach has been uniformly adopted. Methods to gain efficiency and compress the review time period include focusing on a narrow clinical topic and key questions; limiting the literature search; performing single (versus dual) screening of abstracts and full-text articles for relevance; and limiting the analysis and synthesis. In order to maintain the scientific integrity, including transparency, of rapid evidence syntheses, it is imperative that procedures used to streamline standard systematic review methods are prespecified, based on sound review principles and empiric evidence when possible, and provide the end user with an accurate and comprehensive synthesis. The collection of clinical preventive service recommendations maintained by the U.S. Preventive Services Task Force, along with its commitment to rigorous methods development, provide a unique opportunity to refine, implement, and evaluate rapid evidence synthesis methods and add to an emerging evidence base on rapid review methods. This paper summarizes the U.S. Preventive Services Task Force's use of rapid review methodology, its criteria for selecting topics for rapid evidence syntheses, and proposed methods to streamline the review process. Copyright © 2018 American Journal of Preventive Medicine. All rights reserved.

  3. Experience in education and training of gas engineers in Russia

    International Nuclear Information System (INIS)

    Basniev, K.; Vladimirov, A.

    1997-01-01

    Experience gained in training and retraining of engineers for gas industry is considered in the report. The report contains the material on modern state of higher technical education in Russia in view of the reforms taking place in this country. The report deals with questions concerning the experience gained in a specialized training of gas engineers at higher educational establishments of Russia including training of specialists for foreign countries. Conditions under which retraining of engineers involved in gas industry takes place are presented in the report. The report is based mainly on the experience gained by the Russian leading higher educational establishment of oil and gas profile, that is the State Gubkin Oil and Gas Academy. (au)

  4. Inappropriate gestational weight gain among teenage pregnancies: prevalence and pregnancy outcomes.

    Science.gov (United States)

    Vivatkusol, Yada; Thavaramara, Thaovalai; Phaloprakarn, Chadakarn

    2017-01-01

    To study the prevalence and pregnancy outcomes of inappropriate gestational weight gain (GWG) among teenage pregnant women. A retrospective descriptive study was conducted on 2,165 teenage pregnant women who attended our antenatal clinic between January 2007 and August 2015. Adverse pregnancy outcomes, including maternal and neonatal outcomes of women with inappropriate GWG, including underweight and overweight, were studied and compared with those of women with appropriate GWG. Complete data of 1,943 women were obtained. Among these women, the mean age was 17.4±1.4 years and mean body mass index at first visit was 19.1±3.0 kg/m 2 . The prevalence of inappropriate GWG was 61.7%. Underweight women were more likely to experience anemia and preterm delivery, whereas overweight women required more cesarean sections because of cephalopelvic disproportion and preeclampsia, compared to women with appropriate weight gain (all P teenage pregnancies showed inappropriate GWG. GWG had a significant impact on pregnancy outcomes.

  5. A qualitative study of gestational weight gain goal setting.

    Science.gov (United States)

    Criss, Shaniece; Oken, Emily; Guthrie, Lauren; Hivert, Marie-France

    2016-10-20

    Gestational weight gain (GWG) is an important predictor of short and long-term pregnancy outcomes for both mother and child, and women who set a GWG goal are more likely to gain within recommended ranges. Little information is available regarding potentially modifiable factors that underlie a woman's GWG goals. Our aims were to explore women's perceptions regarding factors that affect GWG, their understanding of appropriate GWG, their goal-setting experiences including patient-health care provider (HCP) conversations, and supportive interventions they would most like to help them achieve the recommended GWG. We conducted nine in-depth interviews and seven focus groups with a total of 33 Boston, Massachusetts (MA) area women who were pregnant and had delivered within the prior 6 months. We recorded and transcribed all interviews. Two investigators independently coded resulting transcripts. We managed data using MAXQDA2 and conducted a content analysis. Perceived factors that contributed to GWG goal-setting included the mother's weight control behaviors concerning exercise and diet-including a "new way of eating for two" and "semblance of control", experiences during prior pregnancies, conversations with HCPs, and influence from various information sources. Women focused on behaviors with consistent messaging across multiple sources of information, but mainly trusted their HCP, valued one-to-one conversations with them about GWG, preferred that the HCP initiate the conversation about GWG goals, and would be open to have the conversation started based on visual aid based on their own GWG progression. Pregnant women highly value discussions with their HCP to set GWG goals. Pregnant women view their clinicians as the most reliable source of information and believe that clinicians should open weight-related discussions throughout pregnancy.

  6. Radiation hardness of thin Low Gain Avalanche Detectors

    Science.gov (United States)

    Kramberger, G.; Carulla, M.; Cavallaro, E.; Cindro, V.; Flores, D.; Galloway, Z.; Grinstein, S.; Hidalgo, S.; Fadeyev, V.; Lange, J.; Mandić, I.; Medin, G.; Merlos, A.; McKinney-Martinez, F.; Mikuž, M.; Quirion, D.; Pellegrini, G.; Petek, M.; Sadrozinski, H. F.-W.; Seiden, A.; Zavrtanik, M.

    2018-05-01

    Low Gain Avalanche Detectors (LGAD) are based on a n++-p+-p-p++ structure where an appropriate doping of the multiplication layer (p+) leads to high enough electric fields for impact ionization. Gain factors of few tens in charge significantly improve the resolution of timing measurements, particularly for thin detectors, where the timing performance was shown to be limited by Landau fluctuations. The main obstacle for their operation is the decrease of gain with irradiation, attributed to effective acceptor removal in the gain layer. Sets of thin sensors were produced by two different producers on different substrates, with different gain layer doping profiles and thicknesses (45, 50 and 80 μm). Their performance in terms of gain/collected charge and leakage current was compared before and after irradiation with neutrons and pions up to the equivalent fluences of 5 ṡ 1015 cm-2. Transient Current Technique and charge collection measurements with LHC speed electronics were employed to characterize the detectors. The thin LGAD sensors were shown to perform much better than sensors of standard thickness (∼300 μm) and offer larger charge collection with respect to detectors without gain layer for fluences gain prolongs the beneficial performance of LGADs. Pions were found to be more damaging than neutrons at the same equivalent fluence, while no significant difference was found between different producers. At very high fluences and bias voltages the gain appears due to deep acceptors in the bulk, hence also in thin standard detectors.

  7. Rapid contextual conditioning in autoshaping.

    Science.gov (United States)

    Balsam, P D; Schwartz, A L

    1981-10-01

    Two experiments are reported which investigate the speed of contextual conditioning in autoshaping. In both experiments, a procedure was employed in which ring doves were magazine trained in one context prior to the manipulation of background values in a second context. In Experiment 1, subjects were exposed to 4, 8, 64, 128, or 256 US-only presentations prior to autoshaping. Acquisition speed and maintained response measures were monotonically related to the number of pretraining trials. Subjects in Group 4 acquired the key-peck response fastest, and retardation was maximal within 64 pretraining trials. In Experiment 2, subjects given 20 pretraining trials were significantly more retarded than subjects given 2 pretraining trials, but only when pretraining and testing were conducted in the same context. Overall, the results of these experiments show that in autoshaping, contextual conditioning is very rapid; this demonstrates the plausibility of theoretical accounts of Pavlovian conditioning which assert that the development of the conditioned response depends on the associative values of both the CS and background stimuli.

  8. Space-Time Trellis Coded 8PSK Schemes for Rapid Rayleigh Fading Channels

    Directory of Open Access Journals (Sweden)

    Salam A. Zummo

    2002-05-01

    Full Text Available This paper presents the design of 8PSK space-time (ST trellis codes suitable for rapid fading channels. The proposed codes utilize the design criteria of ST codes over rapid fading channels. Two different approaches have been used. The first approach maximizes the symbol-wise Hamming distance (HD between signals leaving from or entering to the same encoder′s state. In the second approach, set partitioning based on maximizing the sum of squared Euclidean distances (SSED between the ST signals is performed; then, the branch-wise HD is maximized. The proposed codes were simulated over independent and correlated Rayleigh fading channels. Coding gains up to 4 dB have been observed over other ST trellis codes of the same complexity.

  9. From struggles to resource gains in interprofessional service networks: Key findings from a multiple case study.

    Science.gov (United States)

    Toiviainen, Hanna; Kira, Mari

    2017-07-01

    In interprofessional service networks, employees cross professional boundaries to collaborate with colleagues and clients with expertise and values different from their own. It can be a struggle to adopt shared work practices and deal with "multivoicedness." At the same time, networks allow members to engage in meaningful service provision, gain a broader understanding of the service provided, and obtain social support. Intertwined network struggles and resource gains have received limited attention in the interprofessional care literature to date. The aim of the study was to investigate the learning potential of the co-existing struggles and resource gains. This article reports findings from two interprofessional networks. Interviews were conducted with 19 employees and thematically analysed. Three types of struggles and six types of resource gains of networking were identified. The struggles relate, first, to the assumptions of networking following similar practices to those in a home organisation; second, to the challenges of dealing with the multivoicedness of networking; and, third, to the experienced gap between the networking ideals and the reality of cooperation. At the same time, the network members experience gains in emotional resources (e.g., stronger sense of meaningfulness at work), cognitive resources (e.g., understanding the customer needs from alternative perspectives), and social resources (e.g., being able to rely on other professionals' competence). Learning potential emerged from the dynamics between coexisting struggles and resource gains.

  10. Ricardian Productivity Differences and the Gains from Trade

    OpenAIRE

    Andrei A. Levchenko; Jing Zhang

    2013-01-01

    This paper evaluates the role of sectoral heterogeneity in determining the gains from trade. We first show analytically that in the presence of sectoral Ricardian comparative advantage, a one- sector sufficient statistic formula that uses total trade volumes as a share of total absorption systematically understates the true gains from trade. Greater relative sectoral productivity differences lead to larger disparities between the gains implied by the one-sector formula and the true gains. Usi...

  11. Active Microwave Metamaterials Incorporating Ideal Gain Devices

    Directory of Open Access Journals (Sweden)

    Hao Xin

    2010-12-01

    Full Text Available Incorporation of active devices/media such as transistors for microwave and gain media for optics may be very attractive for enabling desired low loss and broadband metamaterials. Such metamaterials can even have gain which may very well lead to new and exciting physical phenomena. We investigate microwave composite right/left-handed transmission lines (CRLH-TL incorporating ideal gain devices such as constant negative resistance. With realistic lumped element values, we have shown that the negative phase constant of this kind of transmission lines is maintained (i.e., left-handedness kept while gain can be obtained (negative attenuation constant of transmission line simultaneously. Possible implementation and challenging issues of the proposed active CRLH-TL are also discussed.

  12. Nucleus accumbens response to gains in reputation for the self relative to gains for others predicts social media use.

    Science.gov (United States)

    Meshi, Dar; Morawetz, Carmen; Heekeren, Hauke R

    2013-01-01

    Our reputation is important to us; we've experienced natural selection to care about our reputation. Recently, the neural processing of gains in reputation (positive social feedback concerning one's character) has been shown to occur in the human ventral striatum. It is still unclear, however, how individual differences in the processing of gains in reputation may lead to individual differences in real-world behavior. For example, in the real-world, one way that people currently maintain their reputation is by using social media websites, like Facebook. Furthermore, Facebook use consists of a social comparison component, where users observe others' behavior and can compare it to their own. Therefore, we hypothesized a relationship between the way the brain processes specifically self-relevant gains in reputation and one's degree of Facebook use. We recorded functional neuroimaging data while participants received gains in reputation, observed the gains in reputation of another person, or received monetary reward. We demonstrate that across participants, when responding to gains in reputation for the self, relative to observing gains for others, reward-related activity in the left nucleus accumbens predicts Facebook use. However, nucleus accumbens activity in response to monetary reward did not predict Facebook use. Finally, a control step-wise regression analysis showed that Facebook use primarily explains our results in the nucleus accumbens. Overall, our results demonstrate how individual sensitivity of the nucleus accumbens to the receipt of self-relevant social information leads to differences in real-world behavior.

  13. THE EFFECT OF CALF STARTER RATION FOR PRE-WEANING ONGOLE GRADE (PO CALVES ON BODY WEIGHT GAIN

    Directory of Open Access Journals (Sweden)

    E. Winarti

    2016-12-01

    Full Text Available The objective of study was to determine the effect of calf starter in the pre-weaning calves against the daily body weight gain. Twenty Ongole grade (PO calves age of 1 month divided into 4 treatment groups of feed, 5 calves for each treatment. Treatment (P1 fed with extra soybean groats; (P2 soybean groats 50% + Gliricidia 50%; (P3 soybean groats 50%+ rice bran 50%; (P4 soybean groats 50%+ rejected bread 50%. Calf starter was given at age 1 month to 3 months. Observation was carried out on calves daily weight gain. This experiment was designed in Completely Randomized Design. Data was  analyzed by analysis of variance and continued Least Significant Difference Test. Statistical analysis showed that feed of (P <0.05 significantly affected the daily weight gain of the calves. Results of the study can be concluded that calf starter with soya groats provide the best daily weight gain of pre-weaning calf.

  14. Preventing Excessive Gestational Weight Gain and Postpartum Weight Retention.

    LENUS (Irish Health Repository)

    O’Dwyer, V

    2017-10-01

    regnancy and the postpartum period are unique opportunities to promote healthy lifestyle choices including a healthy diet and regular exercise. This is especially important for those who are overweight or obese. Women are weighed at their first antenatal visit and body mass index (BMI) calculated, but not all hospitals routinely weigh women throughout pregnancy. A qualitative Dublin study examined experiences of routine weighing during antenatal care. This study found that women expected to be weighed during pregnancy and postpartum. The benefits of this included providing reassurance and minimising postpartum weight retention. Furthermore, women were eager to receive more information about healthy lifestyle interventions and gestational weight gain (GWG) from healthcare professionals

  15. Rapid determination of strontium-89 and strontium-90

    International Nuclear Information System (INIS)

    Hellmuth, K.H.

    1987-05-01

    The main purpose of this study was to run experiments on rapid methods for radiostrontium determination. The aim was also to check the order of magnitude of radiostrontium directly available to plant uptake by roots. A brief inspection of the methods available showed that there is no ideal rapid method. Paying attention to interference from other nuclides, the 90 Sr content of a variety of substances, such as milk, grass and soil could be determined by a two step extraction method with tributyl phosphate. Despite the short waiting time needed for the necessary ingrowth of 90 Y, the first results were available soon after the accident. Comparison with the results obtained by the conventional nitrate separation method later showed the firs results to be fairly accurate. One of the important radionuclides, 89 Sr, could not be determined with the rapid methods used. It was evident from our results that the fallout from Chernobyl contained only a negligible amount of 90 Sr. The levels in soil, grass and milk indicated that the increase of 90 Sr as a result of the accident was within the limits of error of the measurements. The few air-filter samples analysed, however, could not be assessed because of interference from Ce isotopes. Another rapid separation method used for samples with a low Ca content, such as wet and dry deposition using the extraction of Sr as thenoyltrifluoracetylacetonate and subsequent liquid scintillation counting, was not successful under conditions of fresh fallout. Experiences after the reactor accident clearly show that there is a need to develop rapid methods for 89,90 Sr determination

  16. Online Dynamic Balance Technology for High Speed Spindle Based on Gain Parameter Adaption and Scheduling Control

    Directory of Open Access Journals (Sweden)

    Shihai Zhang

    2018-06-01

    Full Text Available Unbalance vibration is one of the main vibration forms of a high speed machine tool spindle. The overlarge unbalance vibration will have some adverse effects on the working life of the spindle system and the surface quality of the work-piece. In order to reduce the unbalance of a high speed spindle system, a pneumatic online dynamic balance device and its control system are presented in the paper. To improve the balance accuracy and adaptation of the balance system, the gain parameter adaption and scheduling control method are proposed first, and then the different balance effects of the influence coefficient method and the gain scheduling control method are compared through many dynamic balance experiments of the high speed spindle. The experimental results indicate that the gain parameters can be changed timely according to the transformation of the speed and kinetic parameters of the spindle system. The balance accuracy can be improved for a high speed spindle with time-varying characteristics, based on the adaptive gain scheduling control method.

  17. Classroom Evaluation of a Rapid Prototyping System.

    Science.gov (United States)

    Tennyson, Stephen A.; Krueger, Thomas J.

    2001-01-01

    Introduces rapid prototyping which creates virtual models through a variety of automated material additive processes. Relates experiences using JP System 5 in freshman and sophomore engineering design graphics courses. Analyzes strengths and limitations of the JP System 5 and discusses how to use it effectively. (Contains 15 references.)…

  18. Antenatal weight management: Diet, physical activity, and gestational weight gain in early pregnancy.

    Science.gov (United States)

    Swift, Judy A; Langley-Evans, Simon C; Pearce, Jo; Jethwa, Preeti H; Taylor, Moira A; Avery, Amanda; Ellis, Sarah; McMullen, Sarah; Elliott-Sale, Kirsty J

    2017-06-01

    to investigate women's physical activity levels, diet and gestational weight gain, and their experiences and motivations of behavior change. analysis of cross-sectional data collected during a longitudinal, cohort study examining physiological, psychological, sociodemographic, and self-reported behavioural measures relating to bodyweight. women recruited from routine antenatal clinics at the Nottingham University Hospitals NHS Trust. 193 women ≤27 weeks gestation and aged 18 years or over. MEASUREMENTS & FINDINGS: measurements included weight and height, the Dietary Instrument for Nutrition Education (Brief Version), the International Physical Activity Questionnaire (Short Form), and open questions of perceptions of behaviour change. 50.3% (n=97) were overweight/obese, and women gained 0.26kg/wk (IQR 0.34kg/wk) since conception. The majority consumed low levels of fat (n=121; 63.4%), high levels of unsaturated fat (n=103; 53.9%), and used a dietary supplement (n=166; 86.5%). However, 41% (n=76) were inactive, 74.8% (n=143) did not consume high levels of fibre, and 90.0% (n=171) consumed less than 5 portions of fruit and vegetables a day. Body mass index category was not associated with diet, physical activity levels, or gestational weight gain. Themes generated from open-questions relating to behaviour change were: (1) Risk management, (2) Coping with symptoms, (3) Self-control, (4) Deviation from norm, (5) Nature knows best. early pregnancy is a period of significant and heterogeneous behaviour change, influenced by perceptions of risk and women's lived experience. Behaviour was influenced not only by perceptions of immediate risk to the fetus, but also by the women's lived experience of being pregnant. There are exciting opportunities to constructively reframe health promotion advice relating to physical activity and diet in light of women's priorities. The need for individualized advice is highlighted, and women across all body mass index categories would

  19. Brillouin gain enhancement in nano-scale photonic waveguide

    Science.gov (United States)

    Nouri Jouybari, Soodabeh

    2018-05-01

    The enhancement of stimulated Brillouin scattering in nano-scale waveguides has a great contribution in the improvement of the photonic devices technology. The key factors in Brillouin gain are the electrostriction force and radiation pressure generated by optical waves in the waveguide. In this article, we have proposed a new scheme of nano-scale waveguide in which the Brillouin gain is considerably improved compared to the previously-reported schemes. The role of radiation pressure in the Brillouin gain was much higher than the role of the electrostriction force. The Brillouin gain strongly depends on the structural parameters of the waveguide and the maximum value of 12127 W-1 m-1 is obtained for the Brillouin gain.

  20. Surface plasmon enhancement in gold nanoparticles in the presence of an optical gain medium: an analysis

    Energy Technology Data Exchange (ETDEWEB)

    Sathiyamoorthy, K; Sreekanth, K V; Sidharthan, R; Murukeshan, V M [School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798 (Singapore); Xing Bengang, E-mail: mmurukeshan@ntu.edu.sg [Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 (Singapore)

    2011-10-26

    The localized surface plasmon (LSP) enhancement in a gold nanoparticle is demonstrated in this paper. The enhancement of LSP is influenced by both size and the dielectric gain medium surrounding the nanoparticles. The nanoparticle is found to induce plasmonic enhancement of varying degrees depending on its size, and it is inferred that a gold nanoparticle of size 60 nm exhibits the maximum LSP for 532 nm excitation. Singularity due to cancellation of SP loss by an infinite gain medium and LSP enhancement are studied using a pump-probe Rayleigh scattering experiment. Gold nanoparticles of average size 60 nm exhibit the lowest threshold power to observe Rayleigh scattering. Furthermore, compared with the bare nanoparticles, a 12.5 fold enhancement of LSP is observed when the nanoparticle of average size 60 nm is kept in the gain medium.

  1. Method and system for edge cladding of laser gain media

    Science.gov (United States)

    Bayramian, Andrew James; Caird, John Allyn; Schaffers, Kathleen Irene

    2014-03-25

    A gain medium operable to amplify light at a gain wavelength and having reduced transverse ASE includes an input surface and an output surface opposing the input surface. The gain medium also includes a central region including gain material and extending between the input surface and the output surface along a longitudinal optical axis of the gain medium. The gain medium further includes an edge cladding region surrounding the central region and extending between the input surface and the output surface along the longitudinal optical axis of the gain medium. The edge cladding region includes the gain material and a dopant operable to absorb light at the gain wavelength.

  2. Monitoring of radioactivity in foodstuffs: experience gained and recommendations

    International Nuclear Information System (INIS)

    Mamoon, A.M.; Abdulfattah, A.F.; Abulfaraj, W.H.; Abdul-Majid, S.; Al-Johani, M.; Abubakar, K.M.

    1988-01-01

    The Chernobyl reactor accident released large amounts of radioactivity that was carried by winds across international boundaries. Soils and surface waters as well as vegetation and grazing animals in neighbouring countries to the Soviet Union were subject to radioactive contamination in various degrees. Saudi Arabia imports much of its foodstuffs from European countries and about 75% of the imported foodstuffs come through western ports of the country. Hence the Government of Saudi Arabia took appropriate measures to ensure safety of imported foodstuffs. King Abdulaziz University (KAU) was directed by the government at about mid-June 1986, to carry out radioactivity inspections of food items reaching Jeddah, Yanbu and Jizan seaports as well as food arrivals at King Abdulaziz International Airport at Jeddah. Parallel responsibilities were assigned to other universities and King Abdulaziz City for Science and Technology, for radioactivity inspections of imported foodstuffs reaching ports or inlets in their respective areas. In applying the measures and controls enacted by the government against importation of radioactively contaminated foodstuffs, much management experience was acquired and some of it is rather unique to Saudi Arabia

  3. How invasive is TMJ double-contrast arthrography in combination with cinematography? Patient discomfort versus known diagnostic gain.

    Science.gov (United States)

    Engelke, W; Mommaerts, M

    1990-04-01

    There is no doubt that double-contrast TMJ fluoroscopic tomography enables a differential diagnosis and treatment in internal derangement pathosis. Its indication is, apart from the expected diagnostic gain, also determined by the degree of its invasiveness, and other alternative diagnostics being available (nuclear magnetic resonance). Data on patient discomfort and complications were gathered in 63 arthrotomographies; pain sensations and mandibular mobility, during and after the procedure in particular, were studied. We consider, along with Westesson, the procedure to be less invasive than commonly considered, once the surgeon-radiologist has gained enough experience.

  4. Inappropriate gestational weight gain among teenage pregnancies: prevalence and pregnancy outcomes

    Directory of Open Access Journals (Sweden)

    Vivatkusol Y

    2017-05-01

    Full Text Available Yada Vivatkusol, Thaovalai Thavaramara, Chadakarn Phaloprakarn Department of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand Objective: To study the prevalence and pregnancy outcomes of inappropriate gestational weight gain (GWG among teenage pregnant women.Methods: A retrospective descriptive study was conducted on 2,165 teenage pregnant women who attended our antenatal clinic between January 2007 and August 2015. Adverse pregnancy outcomes, including maternal and neonatal outcomes of women with inappropriate GWG, including underweight and overweight, were studied and compared with those of women with appropriate GWG.Results: Complete data of 1,943 women were obtained. Among these women, the mean age was 17.4±1.4 years and mean body mass index at first visit was 19.1±3.0 kg/m2. The prevalence of inappropriate GWG was 61.7%. Underweight women were more likely to experience anemia and preterm delivery, whereas overweight women required more cesarean sections because of cephalopelvic disproportion and preeclampsia, compared to women with appropriate weight gain (all P<0.001. The rates of gestational diabetes mellitus among women who were underweight, overweight, or appropriate weight were not significantly different.Conclusion: More than 60% of teenage pregnancies showed inappropriate GWG. GWG had a significant impact on pregnancy outcomes. Keywords: prevalence, pregnancy outcome, inappropriate gestational weight gain, teenage pregnancy

  5. Predictors of Language Gains Among School-Age Children With Language Impairment in the Public Schools.

    Science.gov (United States)

    Justice, Laura M; Jiang, Hui; Logan, Jessica A; Schmitt, Mary Beth

    2017-06-10

    This study aimed to identify child-level characteristics that predict gains in language skills for children with language impairment who were receiving therapy within the public schools. The therapy provided represented business-as-usual speech/language treatment provided by speech-language pathologists in the public schools. The sample included 272 kindergartners and first-graders with language impairment who participated in a larger study titled "Speech-Therapy Experiences in the Public Schools." Multilevel regression analyses were applied to examine the extent to which select child-level characteristics, including age, nonverbal cognition, memory, phonological awareness, vocabulary, behavior problems, and self-regulation, predicted children's language gains over an academic year. Pratt indices were computed to establish the relative importance of the predictors of interest. Phonological awareness and vocabulary skill related to greater gains in language skills, and together they accounted for nearly 70% of the explained variance, or 10% of total variance at child level. Externalizing behavior, nonverbal cognition, and age were also potentially important predictors of language gains. This study significantly advances our understanding of the characteristics of children that may contribute to their language gains while receiving therapy in the public schools. Researchers can explore how these characteristics may serve to moderate treatment outcomes, whereas clinicians can assess how these characteristics may factor into understanding treatment responses.

  6. Net energy gain from DT fusion

    International Nuclear Information System (INIS)

    Buende, R.

    1985-01-01

    The net energy which can be gained from an energy raw material by means of a certain conversion system is deduced as the figure-of-merit which adequately characterizes the net energy balance of utilizing an energy source. This potential net energy gain is determined for DT fusion power plants. It is represented as a function of the degree of exploitation of the energy raw material lithium ore and is compared with the net energy which can be gained with LW and FBR power plants by exploiting uranium ore. The comparison clearly demonstrates the net energetic advantage of DT fusion. A sensitivity study shows that this holds even if the energy expenditure for constructing and operating is drastically increased

  7. WELFARE GAIN FROM CARBON TAX APPLIED TO LEISURE AIR TRAFFIC

    Directory of Open Access Journals (Sweden)

    Roberto Rendeiro Martín-Cejas

    2017-12-01

    Full Text Available ABSTRACTThe rapid growth in the air transport required satisfying the increased demand for tourism become a factor of unsustainability due to the substantial environmental impact that supports such a development. There is the need to establish an alternative to the traditional air transport pricing structure that reflects the true cost that air market operators impose on others. This paper analyses one application of a Carbon tax by considering the CO2 emission costs as a valuable input. A tentative tax on CO2 emissions from air transport is calculated considering its applications in leisure air transport market. Finally, one of the main conclusions of the analysis performed is that the available evidence suggests that international aviation emissions should be restricted. In this case, a Ramsey pricing structure, which involved aviation users bearing the environmental costs, would work reasonably well at restricting inefficient demand and produce a reasonable welfare gain respect to the do-nothing scenerywill be pointed out.

  8. Nucleus accumbens response to gains in reputation for the self relative to gains for others predicts social media use

    Directory of Open Access Journals (Sweden)

    Dar eMeshi

    2013-08-01

    Full Text Available Our reputation is important to us; we’ve experienced natural selection to care about our reputation. Recently, the neural processing of gains in reputation (positive social feedback concerning one’s character has been shown to occur in the human ventral striatum. It is still unclear, however, how individual differences in the processing of gains in reputation may lead to individual differences in real-world behavior. For example, in the real-world, one way that people currently maintain their reputation is by using social media websites, like Facebook. Furthermore, Facebook use consists of a social comparison component, where users observe others’ behavior and can compare it to their own. Therefore, we hypothesized a relationship between the way the brain processes specifically self-relevant gains in reputation and one’s degree of Facebook use. We recorded functional neuroimaging data while participants received gains in reputation, observed the gains in reputation of another person, or received monetary reward. We demonstrate that across participants, when responding to gains in reputation for the self, relative to observing gains for others, reward-related activity in the left nucleus accumbens predicts Facebook use. However, nucleus accumbens activity in response to monetary reward did not predict Facebook use. Finally, a control step-wise regression analysis showed that Facebook use primarily explains our results in the nucleus accumbens. Overall, our results demonstrate how individual sensitivity of the nucleus accumbens to the receipt of self-relevant social information leads to differences in real-world behavior.

  9. Rapidity distributions of hadrons in proton-nucleus collisions

    Science.gov (United States)

    Pirner, H. J.; Kopeliovich, B. Z.

    2018-05-01

    We study proton-lead collisions with a new model for the Fock states of the incoming proton. The number of collisions that the proton experiences selects the appropriate Fock state of the proton, which generates a multiple of p p -like rapidity distributions. We take as input the p p maximum entropy distributions, shifting the respective center-of-mass rapidities and reducing the available energies. A comparison with existing data at 5 TeV is made, and results for 8 TeV are presented. We also explore the high multiplicity data in this model.

  10. Photomultiplier gain stabilisation

    International Nuclear Information System (INIS)

    Le Baud, P.; Sautiez, B.

    1958-07-01

    By the control and adjustment of magnetic deflection applied to the electron beam of a photomultiplier it has proved possible to flatten the gain curve, forming plateaux at levels dependent upon the voltage at intake. It should be possible to add this simple device to most photomultipliers on the market today. (author) [fr

  11. When, How and Why is Loss-Framing More Effective than Gain- and Non-Gain-Framing in the Promotion of Detection Behaviors?

    OpenAIRE

    Bosone, Lucia; Martinez, Frédéric

    2017-01-01

    This short paper aims to untangle the effect of loss-framing versus gain and non-gain; explaining when, how and why it influences individuals’ intentions to engage in cholesterol screening. We argue that framing-effects are (1) significant only when individuals perceive the issue to be highly relevant and (2) are mediated by perceived negative consequences (resulting from undergoing the test) and response-efficacy. In a 2(issue-relevance: high vs low) × 3(framing: gain vs non-gain vs loss) ex...

  12. P300 amplitude variation is related to ventral striatum BOLD response during gain and loss anticipation: an EEG and fMRI experiment.

    Science.gov (United States)

    Pfabigan, Daniela M; Seidel, Eva-Maria; Sladky, Ronald; Hahn, Andreas; Paul, Katharina; Grahl, Arvina; Küblböck, Martin; Kraus, Christoph; Hummer, Allan; Kranz, Georg S; Windischberger, Christian; Lanzenberger, Rupert; Lamm, Claus

    2014-08-01

    The anticipation of favourable or unfavourable events is a key component in our daily life. However, the temporal dynamics of anticipation processes in relation to brain activation are still not fully understood. A modified version of the monetary incentive delay task was administered during separate functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) sessions in the same 25 participants to assess anticipatory processes with a multi-modal neuroimaging set-up. During fMRI, gain and loss anticipation were both associated with heightened activation in ventral striatum and reward-related areas. EEG revealed most pronounced P300 amplitudes for gain anticipation, whereas CNV amplitudes distinguished neutral from gain and loss anticipation. Importantly, P300, but not CNV amplitudes, were correlated to neural activation in the ventral striatum for both gain and loss anticipation. Larger P300 amplitudes indicated higher ventral striatum blood oxygen level dependent (BOLD) response. Early stimulus evaluation processes indexed by EEG seem to be positively related to higher activation levels in the ventral striatum, indexed by fMRI, which are usually associated with reward processing. The current results, however, point towards a more general motivational mechanism processing salient stimuli during anticipation. Copyright © 2014. Published by Elsevier Inc.

  13. Testing theory in practice: a simple experiment

    NARCIS (Netherlands)

    Terpstra, R.; Brezocnik, Z.; Kapus, T.; Ferreira Pires, Luis; Heerink, A.W.; Tretmans, G.J.

    1996-01-01

    In this paper we discuss the experiences gained in conducting a simple testing experiment. The goal of this experiment is to apply the abstract, formal testing framework [8] in a practical setting, and to indicate the critical aspects in its application to realistic testing situations. For that

  14. Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD) Syndrome: A Case Report

    OpenAIRE

    Bagheri; Pourbakhtyaran; Talebi Kiasari; Taherkhanchi; Salarian; Sadeghi

    2016-01-01

    Introduction Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (ROHHAD) is a rare disease. To date, there have been only few reported cases of ROHHAD syndrome. Case Presentation We report a 5-year-old- Iranian girl who had normal growth and development until her 4th year of life. At that time, the patient developed weight gain, constipation, coldness in the extremities, and hyperhidros...

  15. 24 CFR 3280.506 - Heat loss/heat gain.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Heat loss/heat gain. 3280.506... URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.506 Heat loss/heat gain. The manufactured home heat loss/heat gain shall be determined by methods outlined in...

  16. Discrimination and excessive weight gain during pregnancy among Black and Latina young women.

    Science.gov (United States)

    Reid, Allecia E; Rosenthal, Lisa; Earnshaw, Valerie A; Lewis, Tené T; Lewis, Jessica B; Stasko, Emily C; Tobin, Jonathan N; Ickovics, Jeannette R

    2016-05-01

    Excessive weight gain during pregnancy is a major determinant of later life obesity among both Black and Latina women and their offspring. However, psychosocial determinants of this risk, including everyday discrimination, and potential moderators of such effects remain unexplored. We examined the influence of discrimination, a culturally relevant stressor, on odds of gaining weight beyond Institute of Medicine recommendations during pregnancy. Whether the effect was moderated by race/ethnicity, age, or depressive symptoms was also examined. Participants were 413 Black and Latina pregnant young women, ages 14-21 years. Experience with discrimination and all moderators were assessed in the second trimester. Last weight recorded in the third trimester was abstracted from medical records and used to determine excessive weight gain. Ever experiencing discrimination was associated with a 71% increase in the odds of excessive weight gain. The effect of discrimination was primarily present among women who attributed this treatment to membership in a historically oppressed group (e.g., ethnic minority, female) or to membership in other stigmatized groups (e.g., overweight). The effect of ever experiencing discrimination was not moderated by race/ethnicity or age but was moderated by depressive symptoms. Supporting the perspective of the environmental affordances model, discrimination strongly predicted excessive weight gain when women were low in depressive symptoms but had no effect when women were high in depressive symptoms. The moderating role of depressive symptoms was equivalent for Black and Latina women. Results highlight the role of discrimination in perpetuating weight-related health disparities and suggest opportunities for improving health outcomes among young pregnant women. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Discrimination and Excessive Weight Gain During Pregnancy Among Black and Latina Young Women

    Science.gov (United States)

    Reid, Allecia E.; Rosenthal, Lisa; Earnshaw, Valerie A.; Lewis, Tené T.; Lewis, Jessica B.; Stasko, Emily C.; Tobin, Jonathan N.; Ickovics, Jeannette R.

    2016-01-01

    Rationale Excessive weight gain during pregnancy is a major determinant of later life obesity among both Black and Latina women and their offspring. However, psychosocial determinants of this risk, including everyday discrimination, and potential moderators of such effects remain unexplored. Objective We examined the influence of discrimination, a culturally relevant stressor, on odds of gaining weight beyond Institute of Medicine recommendations during pregnancy. Whether the effect was moderated by race/ethnicity, age, or depressive symptoms was also examined. Method Participants were 413 Black and Latina pregnant young women, ages 14-21 years. Experience with discrimination and all moderators were assessed in the second trimester. Last weight recorded in the third trimester was abstracted from medical records and used to determine excessive weight gain. Results Ever experiencing discrimination was associated with a 71% increase in the odds of excessive weight gain. The effect of discrimination was primarily present among women who attributed this treatment to membership in a historically oppressed group (e.g., ethnic minority, female) or to membership in other stigmatized groups (e.g., overweight). The effect of ever experiencing discrimination was not moderated by race/ethnicity or age but was moderated by depressive symptoms. Supporting the perspective of the environmental affordances model, discrimination strongly predicted excessive weight gain when women were low in depressive symptoms but had no effect when women were high in depressive symptoms. The moderating role of depressive symptoms was equivalent for Black and Latina women. Conclusion Results highlight the role of discrimination in perpetuating weight-related health disparities and suggest opportunities for improving health outcomes among young pregnant women. PMID:27038321

  18. Determinants of Weight Gain During Adjuvant Endocrine Therapy and Association of Such Weight Gain With Recurrence in Long-term Breast Cancer Survivors.

    Science.gov (United States)

    Raghavendra, Akshara; Sinha, Arup K; Valle-Goffin, Janeiro; Shen, Yu; Tripathy, Debu; Barcenas, Carlos H

    2018-02-01

    Weight gain is a negative prognostic factor in breast cancer (BC) patients. The risk factors for weight gain during adjuvant endocrine therapy (ET) and the extent to which such weight gain is associated with disease recurrence remain unclear. We retrospectively identified a cohort of women with a diagnosis of stage I-III, hormone receptor-positive, human epidermal growth factor receptor 2-negative BC from January 1997 to August 2008, who had received initial treatment at the MD Anderson Cancer Center, had completed 5 years of ET, and had remained free of locoregional or distant relapse or contralateral BC for ≥ 5 years after diagnosis. The weight change at the end of 5 years of ET was measured as the percentage of the change in weight from the start of ET, with a weight gain of > 5% considered clinically significant. Multivariable logistic regression and Cox proportional hazards models were used to assess the determinants of such weight gain and the risk of recurrence after 5 years. Of 1282 long-term BC survivors, 432 (33.7%) had a weight gain of > 5% after 5 years of ET. Women who were premenopausal at diagnosis were 1.40 times more likely than women who were postmenopausal at diagnosis to have a weight gain of > 5%. Asian women had the lowest risk of gaining weight. The recurrence risks of patients who had gained weight and those who had not were not significantly different. Premenopausal BC patients had an increased risk of weight gain after 5 years of ET; however, BC patients with a weight gain of > 5% did not have an increased risk of disease recurrence. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Transient optical gain in germanium quantum wells

    Energy Technology Data Exchange (ETDEWEB)

    Chatterjee, Sangam; Lange, Christoph; Koester, Niko S.; Schaefer, Martin; Kira, Mackillo; Koch, Stephan W. [Faculty of Physics and Materials Sciences Center, Philipps-Universitaet Marburg (Germany); Chrastina, Daniel; Isella, Giovanni; Kaenel, Hans von [CNISM, Como (Italy); L-NESS, Dipartimento di Fisica del Politecnico di Milano, Como (Italy); Sigg, Hans [Laboratory for Micro and Nanotecnology, Paul Scherrer Institut, Villigen PSI (Switzerland)

    2010-07-01

    One of today's most-sought goals in semiconductor technology is the monolithic integration of microelectronics and photonics on Si. Optical gain is, in general, not expected for Si and Ge or its alloys due to the indirect nature of the band gap in this material system. Here, we show that Ge/SiGe QWs show transient optical gain and may thus be used as an optically-pumped amplifier at room temperature. Further, the nonequilibrium effects which govern the relaxation dynamics of the optically injected carrier distributions in this material were observed and analyzed using a microscopic many-body theory. Strong non-equilibrium gain was obtained on a sub-100 fs time scale. Long-lived gain arising from {gamma}-point transitions is overcompensated by a process bearing the character of free carrier absorption.

  20. Optical properties of nanowire metamaterials with gain

    DEFF Research Database (Denmark)

    Isidio de Lima, Joaquim Junior; Adam, Jost; Rego, Davi

    2016-01-01

    The transmittance, reflectance and absorption of a nanowire metamaterial with optical gain are numerically simulated and investigated. It is assumed that the metamaterial is represented by aligned silver nanowires embedded into a semiconductor matrix, made of either silicon or gallium phosphide....... The gain in the matrix is modeled by adding a negative imaginary part to the dielectric function of the semiconductor. It is found that the optical coefficients of the metamaterial depend on the gain magnitude in a non-trivial way: they can both increase and decrease with gain depending on the lattice...... constant of the metamaterial. This peculiar behavior is explained by the field redistribution between the lossy metal nanowires and the amplifying matrix material. These findings are significant for a proper design of nanowire metamaterials with low optical losses for diverse applications....

  1. Learning to walk with an adaptive gain proportional myoelectric controller for a robotic ankle exoskeleton.

    Science.gov (United States)

    Koller, Jeffrey R; Jacobs, Daniel A; Ferris, Daniel P; Remy, C David

    2015-11-04

    humans to adopt gait patterns different from their normal choices for locomotion. In our specific experiment, subjects increased ankle power and decreased hip power to walk with a reduction in metabolic cost. Future exoskeleton devices that rely on proportional myolectric control are likely to demonstrate improved performance by including an adaptive gain.

  2. Design of a high-power, high-gain, 2nd harmonic, 22.848 GHz gyroklystron

    Energy Technology Data Exchange (ETDEWEB)

    Veale, M. [University of California, Berkeley, CA, 24720 (United States); Purohit, P. [Qualcomm Technologies, Inc. USA (United States); Lawson, W. [University of Maryland, College Park, MD 20742 (United States)

    2013-08-15

    In this paper we consider the design of a four-cavity, high-gain K-band gyroklystron experiment for high gradient structure testing. The frequency doubling gyroklystron utilizes a beam voltage of 500 kV and a beam current of 200 A from a magnetron injection gun (MIG) originally designed for a lower-frequency device. The microwave circuit features input and gain cavities in the circular TE{sub 011} mode and penultimate and output cavities that operate at the second harmonic in the TE{sub 021} mode. We investigate the MIG performance and study the behavior of the circuit for different values of perpendicular to parallel velocity ratio (α= V{sub ⊥}/ V{sub z}). This microwave tube is expected to be able to produce at least 20 MW of power in 1μs pulses at a repetition rate of at least 120 Hz. A maximum efficiency of 26% and a large signal gain of 58 dB under zero-drive stable conditions were simulated for a velocity ratio equal to 1.35.

  3. Rapid web development using AJAX and Python

    Energy Technology Data Exchange (ETDEWEB)

    Dolgert, A; Gibbons, L; Kuznetsov, V [Cornell University, Ithaca, NY 14853 (United States)], E-mail: vkuznet@gmail.com

    2008-07-15

    We discuss the rapid development of a large scale data discovery service for the CMS experiment using modern AJAX techniques and the Python language. To implement a flexible interface capable of accommodating several different versions of the DBS database, we used a 'stack' approach. Asynchronous JavaScript and XML (AJAX) together with an SQL abstraction layer, template engine, code generation tool and dynamic queries provide powerful tools for constructing interactive interfaces to large amounts of data. We show how the use of these tools, with rapid development in a modern scripting language, improved the scalability and usability of the the search interface for different user communities.

  4. Rapid web development using AJAX and Python

    International Nuclear Information System (INIS)

    Dolgert, A; Gibbons, L; Kuznetsov, V

    2008-01-01

    We discuss the rapid development of a large scale data discovery service for the CMS experiment using modern AJAX techniques and the Python language. To implement a flexible interface capable of accommodating several different versions of the DBS database, we used a 'stack' approach. Asynchronous JavaScript and XML (AJAX) together with an SQL abstraction layer, template engine, code generation tool and dynamic queries provide powerful tools for constructing interactive interfaces to large amounts of data. We show how the use of these tools, with rapid development in a modern scripting language, improved the scalability and usability of the the search interface for different user communities

  5. Experience gained in France on heat recovery from nuclear plants for agriculture and pisciculture

    International Nuclear Information System (INIS)

    Balligand, P.; Le Gouellec, P.; Dumont, M.; Grauby, A.

    1978-01-01

    Since 1972, the Commissariat a l'Energie Atomique, Electricite de France, and the French Ministry of Agriculture have jointly examined the possibility of using thermal wastes from nuclear power plants for the benefit of agricultural production. A new process to heat greenhouses with water at 303 K using a double-wall plastic mulching laid directly on the soil has been successfully used for a few years on several hectares. When necessary, heat pumps are utilized. Very good results have been obtained for tomatoes, cucumbers, flowers, and strawberries, etc. Outdoor soil heating with buried pipes has been tested in Cadarache near an experimental pressurized water reactor for market garden crops and forestry. Gains in precocity and yield have been excellent, especially for asparagus, strawberries, and potatoes. Growing of eels has been four times faster in warm water over one year

  6. Weight gain in women diagnosed with breast cancer.

    Science.gov (United States)

    Demark-Wahnefried, W; Rimer, B K; Winer, E P

    1997-05-01

    This review of the literature indicates that weight gain is a common observation among women after the diagnosis of breast cancer. Gains in weight range from 0 to 50 lb and are influenced by menopausal status; nodal status; and the type, duration, and intensity of treatment. Weight gain appears to be greater among premenopausal women; among those who are node positive; and among those receiving higher dose, longer duration, and multiagent regimens. Psychosocial research suggests that weight gain has a profoundly negative impact on quality of life in patients with breast cancer. Recent findings also suggest that weight gain during therapy may increase the risk of recurrence and decrease survival. Although weight gain in patients with breast cancer is clinically well appreciated, little research has been conducted to investigate the underlying mechanisms of energy imbalance. Changes in rates of metabolism, physical activity, and dietary intake are all plausible mechanisms and call for more research. Further study will provide valuable insight into the problem of weight gain and encourage effective interventions to improve the quality and quantity of life for the woman with breast cancer. Until more is known, however, dietetics practitioners will have to monitor and work individually with patients with breast cancer and use empirical approaches to achieve the important goal of weight management.

  7. Evaluation of performance of select fusion experiments and projected reactors. Final report

    International Nuclear Information System (INIS)

    Miley, G.H.

    1978-10-01

    The performance of NASA Lewis fusion experiments (SUMMA and Bumpy Torus) is compared with other experiments and that necessary for a power reactor. Key parameters cited are gain (fusion power/input power) and the time average fusion power, both of which may be more significant for real fusion reactors than the commonly used Lawson parameter. The NASA devices are over 10 orders of magnitude below the required powerplant values in both gain and time average power. The best experiments elsewhere are also as much as 4 to 5 orders of magnitude low. However, the NASA experiments compare favorably with other alternate approaches that have received less funding than the mainline experiments. The steady-state character and efficiency of plasma heating are strong advantages of the NASA approach. The problem, though, is to move ahead to experiments of sufficient size to advance in gain and average power parameters

  8. Gain Shift Corrections at Chi-Nu

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Tristan Brooks [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Univ. of Massachusetts, Lowell, MA (United States). Dept. of Physics and Applied Physics; Devlin, Matthew James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-08-30

    Ambient conditions have the potential to cause changes in liquid scintillator detector gain that vary with time and temperature. These gain shifts can lead to poor resolution in both energy as well as pulse shape discrimination. In order to correct for these shifts in the Chi-Nu high energy array, a laser system has been developed for calibration of the pulse height signals.

  9. Maximum gain of Yagi-Uda arrays

    DEFF Research Database (Denmark)

    Bojsen, J.H.; Schjær-Jacobsen, Hans; Nilsson, E.

    1971-01-01

    Numerical optimisation techniques have been used to find the maximum gain of some specific parasitic arrays. The gain of an array of infinitely thin, equispaced dipoles loaded with arbitrary reactances has been optimised. The results show that standard travelling-wave design methods are not optimum....... Yagi–Uda arrays with equal and unequal spacing have also been optimised with experimental verification....

  10. Hypercholesterolemia Induced by a PCSK9 Gain-of-Function Mutation Augments Angiotensin II-Induced Abdominal Aortic Aneurysms in C57BL/6 Mice-Brief Report.

    Science.gov (United States)

    Lu, Hong; Howatt, Deborah A; Balakrishnan, Anju; Graham, Mark J; Mullick, Adam E; Daugherty, Alan

    2016-09-01

    Gain-of-function mutations of PCSK9 (proprotein convertase subtilisin/kexin type 9) lead to hypercholesterolemia. This study was to determine whether infection of normocholesterolemic mice with an adeno-associated viral (AAV) vector expressing a gain-of-function mutation of mouse PCSK9 increased angiotensin II (AngII)-induced abdominal aortic aneurysms. In an initial study, male C57BL/6 mice were injected intraperitoneally with either an empty vector or PCSK9 gain-of-function mutation (D377Y). AAV at 3 doses and fed a saturated fat-enriched diet for 6 weeks. Two weeks after AAV injection, mice were infused with AngII for 4 weeks. Plasma PCSK9 concentrations were increased dose dependently in mice injected with AAV containing PCSK9D377Y mutation and positively associated with elevations of plasma cholesterol concentrations. Infection with intermediate and high doses of PCSK9D377Y.AAV led to equivalent increases of maximal width of abdominal aortas in C57BL/6 mice infused with AngII. Therefore, the intermediate dose was used in subsequent experiments. We then determined effects of PCSK9D377Y.AAV infection on 5 normolipidemic mouse strains, demonstrating that C57BL/6 mice were the most susceptible to this AAV infection. PCSK9D377Y.AAV infected male C57BL/6 mice were also compared with age-matched male low-density lipoprotein receptor(-/-) mice. Although plasma cholesterol concentrations were lower in mice infected with PCSK9D377Y.AAV, these mice had equivalent abdominal aortic aneurysmal formation, compared to low-density lipoprotein receptor(-/-) mice. In a separate study, reduced plasma PCSK9 concentrations by PCSK9 antisense oligonucleotides in male low-density lipoprotein receptor(-/-) mice did not influence AngII-induced abdominal aortic aneurysms. AAV-mediated infection with a mouse PCSK9 gain-of-function mutation is a rapid, easy, and efficient approach for inducing hypercholesterolemia and promoting abdominal aortic aneurysms in C57BL/6 mice infused with Ang

  11. Radiation protection aspects gained from the operation of FBTR. Basis for approach and criteria for future LMFBRs

    International Nuclear Information System (INIS)

    Meenakshisundaram, V.; Jose, M. T.

    2008-01-01

    Health Physics experience gained from the operation of Fast Breeder Test Reactor since more than twenty years is outlined. These include area monitoring, stack monitoring, annual discharge of activity released vis-a-vis technical specification limits, personnel monitoring that include man-rem expenditure, waste disposal etc. Basic aspects of Radiation and Air Activity Monitoring System (RAAMS), meant to monitor and record the radiation and air activity levels at various controlled areas in FBTR complex are given. Installation, calibration and usefulness of special monitors, unique to LMFBRs, such as gas flow ion chambers in the Clad Rupture Detection (CRD) argon circuit for detection of gaseous fission products, fume activity monitors in the ventilation ducts to indicate sodium leak / fire, sodium aerosol detection monitors in the primary double envelop sampling line and gas activity monitors are highlighted. Radiologically significant incidents such as minor sodium leak in the primary purification system in 2002 and special operations are reported. The experience gained during successful handling, treatment, and disposal of active primary sodium and decontamination of active sodium bearing components following steam-nitrogen process is brought out. Towards controlling external exposures to occupational workers during maintenance work, the salient features of the study conducted to assess the deposition of radioactive corrosion and activation products and dose rates in the primary sodium pipelines and various components of FBTR, which are housed in B-cells, are highlighted. The environmental aspects of LMFBRs are also briefly outlined. The lessons learnt from the experience gained such as lowering of alarm limit for particulate activity monitors to enable detection of primary sodium leak within reactor containment building, identification of deposition of 54 Mn in the interiors of primary sodium lines as a major contributor to the external dose component, the

  12. Vergence increases the gain of the human angular vestibulo-ocular reflex during peripheral hyposensitivity elicited by cold thermal irrigation.

    Science.gov (United States)

    Tamás, László T; Lundberg, Yunxia W; Büki, Béla

    2018-01-01

    When viewing a far target, the gain of the horizontal vestibulo-ocular reflex (VOR) is around 1.0, but when viewing a near target there is an increased response. It has been shown that while this convergence-mediated modulation is unaffected by canal plugging and clinically practical transmastoid galvanic stimulation, it is eliminated by a partial peripheral gentamicin lesion. The aim of this study was to determine if convergence increases the gain during peripheral hyposensitivity elicited by cold thermal irrigation. The high frequency VOR gain was measured using video head impulse testing immediately after the cold caloric stimulus in 9 healthy human subjects with the lateral semicircular canals oriented approximately earth-vertical. Before caloric irrigation, near viewing (15 cm) increased the average VOR gain by 28% (from 1 to 1.28). Cold (24°C) water irrigation of the right ear decreased the gain to 0.66 (far viewing) and 0.82 (near viewing) (22% difference). Although vergence also increased the gain for impulses to the left to the same degree before caloric stimulus, the caloric irrigation itself (applied to the right ear) did not influence the gain for contralateral impulses. In our experiments vergence increased the gain of the human angular VOR during peripheral hyposensitivity elicited by cold thermal irrigation. These results suggest that cold irrigation does not abolish the function of the nonlinear/phasic vestibular afferent pathway.

  13. Point Information Gain and Multidimensional Data Analysis

    Directory of Open Access Journals (Sweden)

    Renata Rychtáriková

    2016-10-01

    Full Text Available We generalize the point information gain (PIG and derived quantities, i.e., point information gain entropy (PIE and point information gain entropy density (PIED, for the case of the Rényi entropy and simulate the behavior of PIG for typical distributions. We also use these methods for the analysis of multidimensional datasets. We demonstrate the main properties of PIE/PIED spectra for the real data with the examples of several images and discuss further possible utilizations in other fields of data processing.

  14. Adequacy of Prenatal Care and Gestational Weight Gain.

    Science.gov (United States)

    Yeo, SeonAe; Crandell, Jamie L; Jones-Vessey, Kathleen

    2016-02-01

    The goal of prenatal care is to maximize health outcomes for a woman and her fetus. We examined how prenatal care is associated with meeting the 2009 Institute of Medicine (IOM) guidelines for gestational weight gain. The study used deidentified birth certificate data supplied by the North Carolina State Center for Health Statistics. The sample included 197,354 women (≥18 years) who delivered singleton full-term infants in 2011 and 2012. A generalized multinomial model was used to identify how adequate prenatal care was associated with the odds of gaining excessive or insufficient weight during pregnancy according to the 2009 IOM guidelines. The model adjusted for prepregnancy body size, sociodemographic factors, and birth weight. A total of 197,354 women (≥18 years) delivered singleton full-term infants. The odds ratio (OR) for excessive weight gain was 2.44 (95% CI 2.37-2.50) in overweight and 2.33 (95% CI 2.27-2.40) in obese women compared with normal weight women. The OR for insufficient weight gain was 1.15 (95% CI 1.09-1.22) for underweight and 1.34 (95% CI 1.30-1.39) for obese women compared with normal weight women. Prenatal care at the inadequate or intermediate levels was associated with insufficient weight gain (OR: 1.32, 95% CI 1.27-1.38; OR: 1.15, 95% CI 1.09-1.21, respectively) compared with adequate prenatal care. Women with inadequate care were less likely to gain excessive weight (OR: 0.88, 95% CI 0.86-0.91). Whereas prenatal care was effective for preventing insufficient weight gain regardless of prepregnancy body size, educational background, and racial/ethnic group, there were no indications that adequate prenatal care was associated with reduced risk for excessive gestational weight gain. Further research is needed to improve prenatal care programs for preventing excess weight gain.

  15. Qualification Testing Versus Quantitative Reliability Testing of PV - Gaining Confidence in a Rapidly Changing Technology: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, Sarah [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Repins, Ingrid L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hacke, Peter L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Jordan, Dirk [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kempe, Michael D [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Whitfield, Kent [Underwriters Laboratories; Phillips, Nancy [DuPont; Sample, Tony [European Commission; Monokroussos, Christos [TUV Rheinland; Hsi, Edward [Swiss RE; Wohlgemuth, John [PowerMark Corporation; Seidel, Peter [First Solar; Jahn, Ulrike [TUV Rheinland; Tanahashi, Tadanori [National Institute of Advanced Industrial Science and Technology; Chen, Yingnan [China General Certification Center; Jaeckel, Bengt [Underwriters Laboratories; Yamamichi, Masaaki [RTS Corporation

    2017-10-05

    Continued growth of PV system deployment would be enhanced by quantitative, low-uncertainty predictions of the degradation and failure rates of PV modules and systems. The intended product lifetime (decades) far exceeds the product development cycle (months), limiting our ability to reduce the uncertainty of the predictions for this rapidly changing technology. Yet, business decisions (setting insurance rates, analyzing return on investment, etc.) require quantitative risk assessment. Moving toward more quantitative assessments requires consideration of many factors, including the intended application, consequence of a possible failure, variability in the manufacturing, installation, and operation, as well as uncertainty in the measured acceleration factors, which provide the basis for predictions based on accelerated tests. As the industry matures, it is useful to periodically assess the overall strategy for standards development and prioritization of research to provide a technical basis both for the standards and the analysis related to the application of those. To this end, this paper suggests a tiered approach to creating risk assessments. Recent and planned potential improvements in international standards are also summarized.

  16. Quality control of the SiPM in the application of large HEP experiments

    International Nuclear Information System (INIS)

    Li Yongzheng; Cheng Yue; Wang Kaijun; Li Bocheng; Liang Kun; Yang Ru; Han Dejun

    2012-01-01

    Large-scale high-energy physics (HEP) experiments have strict requirements on the reliability, consistency and service life for the detectors, it is imperative to set up a quality control system for the involved Silicon Photomultipliers (SiPMs). The essential parameters of the SiPMs are numerous, including reversed leakage current, breakdown voltage, dark count rate, gain, photon detection efficiency, pulse high distribution, temperature coefficient and optical crosstalk etc., characterizing of SiPM should follow an optimal measurement procedures and rules to realize the rapid screening and strict quality control. This paper will introduce the new progress of 1 mm × 1 mm large dynamic range SiPM developed in the Novel Device Laboratory, Beijing Normal University, as well as the measurement guidelines and procedures from chips to packaged devices. (authors)

  17. Net requirements of energy, protein and macrominerals for weight gain of grazing beef cattle castrated at different ages, with and without supplementation

    Directory of Open Access Journals (Sweden)

    Anilza Andréia da Rocha

    2012-02-01

    Full Text Available The objective of this experiment was to estimate the requirements of energy, protein and macrominerals of grazing crossbreds calves, in Brachiaria decumbens Stapf pasture, castrated at different ages, with and without supplementation. Forty-seven young calves at initial age of 120±30.1 days and 115.3±1.97 kg of live weight were used. To estimate net energy requirements for weight gain, a regression equation between energy retained in the gain and empty body weight gain and metabolic empty body weight was obtained. For estimation of net protein requirements for weight gain, a regression equation was adjusted between protein retained in gain and empty body weight gain and energy content of this gain. Net requirements of Ca, P, Mg and Na for weight gain were determined by the equation Y' = a.b. Xb-1, in which a and b represent the intercept and the coefficient of the alometric equation of macromineral body content prediction, respectively. Neither castration nor concentrate supplementation affects body weight gain net requirements, except the ones of Ca, which were higher for non-castrated animals.

  18. ERP evidence for rapid hedonic evaluation of logos.

    Science.gov (United States)

    Handy, Todd C; Smilek, Daniel; Geiger, Lena; Liu, Cindy; Schooler, Jonathan W

    2010-01-01

    We know that human neurocognitive systems rapidly and implicitly evaluate emotionally charged stimuli. But what about more everyday, frequently encountered kinds of objects, such as computer desktop icons and business logos? Do we rapidly and implicitly evaluate these more prosaic visual images, attitude objects that might only engender a mild sense of liking or disliking, if at all? To address this question, we asked participants to view a set of unfamiliar commercial logos in the context of a target identification task as brain electrical responses to these objects were recorded via event-related potentials (ERPs). Following this task, participants individually identified those logos that were most liked or disliked, allowing us to then compare how ERP responses to logos varied as a function of hedonic evaluation-a procedure decoupling evaluative responses from any normative classification of the logos themselves. In Experiment 1, we found that visuocortical processing manifest a specific bias for disliked logos that emerged within the first 200 msec of stimulus onset. In Experiment 2, we replicated this effect while dissociating normative- and novelty-related influences. Taken together, our results provide direct electrophysiological evidence suggesting that we rapidly and implicitly evaluate commercial branding images at a hedonic level.

  19. Optomechanical transistor with mechanical gain

    Science.gov (United States)

    Zhang, X. Z.; Tian, Lin; Li, Yong

    2018-04-01

    We study an optomechanical transistor, where an input field can be transferred and amplified unidirectionally in a cyclic three-mode optomechanical system. In this system, the mechanical resonator is coupled simultaneously to two cavity modes. We show that it only requires a finite mechanical gain to achieve the nonreciprocal amplification. Here the nonreciprocity is caused by the phase difference between the linearized optomechanical couplings that breaks the time-reversal symmetry of this system. The amplification arises from the mechanical gain, which provides an effective phonon bath that pumps the mechanical mode coherently. This effect is analogous to the stimulated emission of atoms, where the probe field can be amplified when its frequency is in resonance with that of the anti-Stokes transition. We show that by choosing optimal parameters, this optomechanical transistor can reach perfect unidirectionality accompanied with strong amplification. In addition, the presence of the mechanical gain can result in ultralong delay in the phase of the probe field, which provides an alternative to controlling light transport in optomechanical systems.

  20. The OTSC®-clip in revisional endoscopy against weight gain after bariatric gastric bypass surgery.

    Science.gov (United States)

    Heylen, Alex Marie Florent; Jacobs, Anja; Lybeer, Monika; Prosst, Ruediger L

    2011-10-01

    The maintenance of the restrictive component of the Fobi pouch gastric bypass is essential for permanent weight control. Dilatation of the pouch-outlet and of the pouch itself is responsible for substantial weight gain by an increased volume per meal and binge-eating due to the rapid emptying. An endoscopic over-the-scope clip (OTSC®; Ovesco AG, Tübingen, Germany) was applied in 94 patients following gastric bypass and unintended weight gain by dilated gastro-jejunostomy to narrow the pouch-outlet. The OTSC®-clip application was safe and efficient to reduce the pouch-outlet in all cases. Best clinical results were obtained by narrowing the gastro-jejunostomy by placing two clips at opposite sites, hence reducing the outlet of more than 80%. Preferably, the clip approximated the whole thickness of the wall to avoid further dilatation of the anastomosis. Between surgery and OTSC®-clip application the mean BMI dropped from 45.8 (±3.6) to 32.8 (±1.9). At the first follow-up about 3 months (mean 118 days, ±46 days) after OTSC®-clip application the mean BMI was 29.7 (±1.8). At the second follow-up about 1 year (mean 352 days, ±66 days) after OTSC®-clip application the mean BMI was 27.4 (±3.8). The OTSC®-clip for revisional endoscopy after gastric bypass is reliable and effective in treating weight gain due to a dilated pouch-outlet with favorable short- and midterm results.

  1. Stability, gain, and robustness in quantum feedback networks

    International Nuclear Information System (INIS)

    D'Helon, C.; James, M. R.

    2006-01-01

    In this paper we are concerned with the problem of stability for quantum feedback networks. We demonstrate in the context of quantum optics how stability of quantum feedback networks can be guaranteed using only simple gain inequalities for network components and algebraic relationships determined by the network. Quantum feedback networks are shown to be stable if the loop gain is less than one--this is an extension of the famous small gain theorem of classical control theory. We illustrate the simplicity and power of the small gain approach with applications to important problems of robust stability and robust stabilization

  2. Postpartum Depressive Symptoms: Gestational Weight Gain as a Risk Factor for Adolescents Who Are Overweight or Obese.

    Science.gov (United States)

    Cunningham, Shayna D; Mokshagundam, Shilpa; Chai, Hannah; Lewis, Jessica B; Levine, Jessica; Tobin, Jonathan N; Ickovics, Jeannette R

    2018-03-01

    Obesity is a risk factor for adverse physical health outcomes during pregnancy. Much less is known about the association between obesity and maternal mental health. Evidence suggests that prenatal depression is associated with excessive weight gain during pregnancy and that this relationship may vary according to pregravid body mass index (BMI). Young women may be particularly vulnerable to postpartum depression. The objective of this study is to examine the association between prepregnancy BMI, gestational weight gain, and postpartum depressive symptoms among adolescents. Participants were 505 pregnant adolescents aged 14 to 21 years followed during pregnancy and 6 months postpartum. Data were collected via interviews and medical record abstraction. Multilevel linear mixed models were used to test the association between excessive gestational weight gain as defined by National Academy of Medicine Guidelines and postpartum depressive symptoms measured via the validated Center for Epidemiologic Studies Depression (CES-D) scale. Analyses controlled for sociodemographic factors (maternal age, race, ethnicity, relationship status), health behaviors (nutrition, physical activity), prenatal depressive symptoms, and postpartum weight retention. Prepregnancy BMI was classified as follows: 11% underweight, 53% healthy weight, 19% overweight, and 18% obese. One-half (50%) of participants exceeded recommended guidelines for gestational weight gain. Adolescents with excessive gestational weight gain who entered pregnancy overweight or obese had significantly higher postpartum depressive symptoms (β, 2.41; SE, 1.06 vs β, 2.58; SE, 1.08, respectively; both P gain. Adolescents who gained gestational weight within clinically recommended guidelines were not at risk for increased depressive symptoms. Adolescents who enter pregnancy overweight or obese and experience excessive weight gain may be at increased risk for postpartum depressive symptoms. Health care providers should

  3. Gain curves and hydrodynamic modeling for shock ignition

    International Nuclear Information System (INIS)

    Lafon, M.; Ribeyre, X.; Schurtz, G.

    2010-01-01

    Ignition of a precompressed thermonuclear fuel by means of a converging shock is now considered as a credible scheme to obtain high gains for inertial fusion energy. This work aims at modeling the successive stages of the fuel time history, from compression to final thermonuclear combustion, in order to provide the gain curves of shock ignition (SI). The leading physical mechanism at work in SI is pressure amplification, at first by spherical convergence, and by collision with the shock reflected at center during the stagnation process. These two effects are analyzed, and ignition conditions are provided as functions of the shock pressure and implosion velocity. Ignition conditions are obtained from a non-isobaric fuel assembly, for which we present a gain model. The corresponding gain curves exhibit a significantly lower ignition threshold and higher target gains than conventional central ignition.

  4. 5-Aminoimidazole-4-carboxamide ribonucleotide prevents fat gain following the cessation of voluntary physical activity.

    Science.gov (United States)

    Ruegsegger, Gregory N; Sevage, Joseph A; Childs, Thomas E; Grigsby, Kolter B; Booth, Frank W

    2017-11-01

    What is the central question of this study? We investigated whether 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) could prevent acute increases in body fat and changes in omental and subcutaneous adipose tissue following the sudden transition from physical activity to physical inactivity. What is the main finding and its importance? AICAR prevented fat gains following the transition from physical activity to inactivity to levels comparable to rats that remained physically active. AICAR and continuous physical activity produced depot-specific changes in cyclin A1 mRNA and protein that were associated with the prevention of fat gain. These findings suggest that targeting AMP-activated protein kinase signalling could oppose rapid adipose mass growth. The transition from physical activity to inactivity is associated with drastic increases in 'catch-up' fat that in turn foster the development of many obesity-associated maladies. We tested whether 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) treatment would prevent gains in body fat following the sudden transition from a physically active state to an inactive state by locking a voluntary running wheel. Male Wistar rats were either sedentary (SED) or given wheel access for 4 weeks, at which time rats with wheels continued running (RUN), had their wheel locked (WL) or had WL with daily AICAR injection (WL + AICAR) for 1 week. RUN and WL + AICAR prevented gains in body fat compared with SED and WL (P RUN and WL + AICAR compared with SED and WL groups (P run, and that together, continuous physical activity and AICAR could, at least initially in these conditions, exert similar inhibitory effects on adipogenesis in a depot-specific manner. © 2017 The Authors. Experimental Physiology © 2017 The Physiological Society.

  5. Perception of gain in U.S.-Soviet arms control

    International Nuclear Information System (INIS)

    D'Anieri, P.J.

    1991-01-01

    Most current work in the field of international cooperation focuses on the resolution of the 'prisoners dilemma.' Such work begins by assuming that the issues under consideration are defined by absolute gains, where both sides can gain simultaneously. But the realist strand of international relations literature holds that this assumption is suspect - that international relations are usually characterized by relative gains, where gain for one side comes only at the others expense. The model developed here uses the question of absolute versus relative gains not as a theoretical assumption, but as a variable to be measured empirically. The hypothesis is that whether or not the US and the Soviet Union cooperate to limit arms competition is largely determined by whether the two sides define the issue in question as one of absolute or relative gains. The 'perception of gain' hypothesis is compared to explanations at the levels of the international system (rational choice), domestic politics, and individual belief systems. Three case studies are used to compare the strengths and weaknesses of each hypothesis. The findings confirmed that perception of gain is an important independent variable affecting arms control outcomes, but none of the theories were completely supported or rejected

  6. Antidepressants and Weight Gain

    Science.gov (United States)

    ... 2015;37:46. Blumenthal SR, et al. An electronic health records study of long-term weight gain following antidepressant ... your agreement to the Terms and Conditions and Privacy Policy linked below. Terms and Conditions Privacy Policy ...

  7. Exponential gain of randomness certified by quantum contextuality

    Science.gov (United States)

    Um, Mark; Zhang, Junhua; Wang, Ye; Wang, Pengfei; Kim, Kihwan

    2017-04-01

    We demonstrate the protocol of exponential gain of randomness certified by quantum contextuality in a trapped ion system. The genuine randomness can be produced by quantum principle and certified by quantum inequalities. Recently, randomness expansion protocols based on inequality of Bell-text and Kochen-Specker (KS) theorem, have been demonstrated. These schemes have been theoretically innovated to exponentially expand the randomness and amplify the randomness from weak initial random seed. Here, we report the experimental evidence of such exponential expansion of randomness. In the experiment, we use three states of a 138Ba + ion between a ground state and two quadrupole states. In the 138Ba + ion system, we do not have detection loophole and we apply a methods to rule out certain hidden variable models that obey a kind of extended noncontextuality.

  8. Tunable Broadband Acoustic Gain in Piezoelectric Semiconductors at ε-Near-Zero Response

    DEFF Research Database (Denmark)

    Christensen, Johan; Willatzen, Morten

    2015-01-01

    Piezoelectric semiconductors have emerged as materials capable to amplify sound waves when electrons are set to drift at supersonic speeds. Several experiments have demonstrated this behaviour at moderate amplification levels for some intrinsic semiconductors and carrier concentrations......-compensation in metamaterials and applicable for sensing such as nonlinear devices. The paper contains a detailed derivation and discussion of transmission and reflection coefficients for pressure pulses impinging on a semiconductor slab and the acoustic gain enhancement that can be achieved by dynamic switching...

  9. 26 CFR 1.1374-2 - Net recognized built-in gain.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Net recognized built-in gain. 1.1374-2 Section 1...-in gain. (a) In general. An S corporation's net recognized built-in gain for any taxable year is the... considering only its recognized built-in gain, recognized built-in loss, and recognized built-in gain...

  10. Efficiency gains, bounds, and risk in finance

    NARCIS (Netherlands)

    Sarisoy, Cisil

    2015-01-01

    This thesis consists of three chapters. The first chapter analyzes efficiency gains in the estimation of expected returns based on asset pricing models and examines the economic implications of such gains in portfolio allocation exercises. The second chapter provides nonparametric efficiency bounds

  11. Does Adoption of Management Standards Deliver Efficiency Gain in Firms’ Pursuit of Sustainability Performance? An Empirical Investigation of Chinese Manufacturing Firms

    Directory of Open Access Journals (Sweden)

    Xiaoling Wang

    2016-07-01

    Full Text Available Building on longitudinal data from 73 Chinese manufacturing firms during 2009–2012, we assess whether and how firms gain higher efficiency in achieving their sustainability goals by adopting management practice standards (ISO 9001, ISO 14001, and/or OHSAS 18001. We propose four pathways for firms to gain sustainability efficiency in their certification journey: participation, qualitative integration, quantitative expansion, and temporal accumulation. Our results confirm that firms certifying management standards gain higher efficiency in pursuing their sustainability goals than firms without these standards. We also find some support for increased efficiency effect in firms with diverse management systems over firms with only a single certificate in 2011. Finally, our results highlight the experiential and temporal accumulation effect of such efficiency gains, that is, firms with prior certification experience or having a longer certification history demonstrate higher efficiency gains in pursuing their sustainability goals.

  12. Control of the inversionless gain and refractive index in a V-type atom via squeezed vacuum and quantum interference

    International Nuclear Information System (INIS)

    Anton, M.A.; Calderon, Oscar G.; Carreno, F.

    2004-01-01

    In this paper we analyze the steady-state populations and gain lineshape of a V-type three-level atom with a closely spaced excited doublet. The atom is driven by a strong coherent field, a weak probe, and a single broadband squeezed vacuum. We focus our attention in the interplay between the quantum interference and the squeezed field on the probe gain. It is shown that the relative phases between the two coherent fields and the squeezed field play an important role in the optical properties of the atom. Specifically, we find that the probe can experience gain without population inversion for proper values of the parameters characterizing the squeezed field and in the absence of incoherent pumping. The system can be tailored to exhibit multiple dispersion regimes accompanied by negligible gain or absorption over a large bandwidth, a desirable feature for obtaining propagation of pulses with negligible distortion

  13. Extensive intron gain in the ancestor of placental mammals

    Science.gov (United States)

    2011-01-01

    Background Genome-wide studies of intron dynamics in mammalian orthologous genes have found convincing evidence for loss of introns but very little for intron turnover. Similarly, large-scale analysis of intron dynamics in a few vertebrate genomes has identified only intron losses and no gains, indicating that intron gain is an extremely rare event in vertebrate evolution. These studies suggest that the intron-rich genomes of vertebrates do not allow intron gain. The aim of this study was to search for evidence of de novo intron gain in domesticated genes from an analysis of their exon/intron structures. Results A phylogenomic approach has been used to analyse all domesticated genes in mammals and chordates that originated from the coding parts of transposable elements. Gain of introns in domesticated genes has been reconstructed on well established mammalian, vertebrate and chordate phylogenies, and examined as to where and when the gain events occurred. The locations, sizes and amounts of de novo introns gained in the domesticated genes during the evolution of mammals and chordates has been analyzed. A significant amount of intron gain was found only in domesticated genes of placental mammals, where more than 70 cases were identified. De novo gained introns show clear positional bias, since they are distributed mainly in 5' UTR and coding regions, while 3' UTR introns are very rare. In the coding regions of some domesticated genes up to 8 de novo gained introns have been found. Intron densities in Eutheria-specific domesticated genes and in older domesticated genes that originated early in vertebrates are lower than those for normal mammalian and vertebrate genes. Surprisingly, the majority of intron gains have occurred in the ancestor of placentals. Conclusions This study provides the first evidence for numerous intron gains in the ancestor of placental mammals and demonstrates that adequate taxon sampling is crucial for reconstructing intron evolution. The

  14. A wide range and high speed automatic gain control

    International Nuclear Information System (INIS)

    Tacconi, E.; Christiansen, C.

    1993-05-01

    Automatic gain control (AGC) techniques have been largely used since the beginning of electronics, but in most of the applications the dynamic response is slow compared with the carrier frequency. The problem of developing an automatic gain control with high dynamic response and wide control range simultaneously is analyzed in this work. An ideal gain control law, with the property that the total loop gain remains constant independent of the carrier amplitude, is obtained. The resulting AGC behavior is compared by computer simulations with a linear multiplier AGC. The ideal gain control law can be approximated using a transconductance amplifier. A practical circuit that has been used at CERN in the radio frequency loops of the Booster Synchrotron is presented. The circuit has high speed and 80-dB gain control range

  15. Enhanced Gain in Photonic Crystal Amplifiers

    DEFF Research Database (Denmark)

    Ek, Sara; Semenova, Elizaveta; Hansen, Per Lunnemann

    2012-01-01

    We experimentally demonstrate enhanced gain in the slow-light regime of quantum well photonic crystal amplifiers. A strong gain enhancement is observed with the increase of the group refractive index, due to light slow-down. The slow light enhancement is shown in a amplified spontaneous emission....... These results are promising for short and efficient semiconductor optical amplifiers. This effect will also benefit other devices, such as mode locked lasers....

  16. Changes in job strain and subsequent weight gain

    DEFF Research Database (Denmark)

    Vesterlund, Gitte Kingo; Keller, Amélie Cléo; Heitmann, Berit Lilienthal

    2018-01-01

    in 1999 between those who were rarely v. sometimes v. often busy in 1993 (P=0·03), with the largest weight gain in individuals with sustained high busyness in both years. Loss of influence between 1993 and 1999 was associated with larger subsequent weight gain than sustained high influence (P=0......Objective: Obesity as well as job strain is increasing, and job strain might contribute to weight gain. The objective of the current study was to examine associations between longitudinal alterations in the components of job strain and subsequent weight gain. Design: The study was designed...... as a prospective cohort study with three questionnaire surveys enabling measurement of job-strain alterations over 6 years and subsequent measurements of weight gain after further 10 years of follow-up. ANCOVA and trend analyses were conducted. Job demands were measured as job busyness and speed, and control...

  17. Do Gains in Secondary Teachers’ Content Knowledge Provide an ASSET to Student Learning?

    Science.gov (United States)

    Hites, Travis

    2015-01-01

    During the Summer of 2013, a group of East Texas middle and high school science teachers attended the first year of the Astronomy Summer School of East Texas (ASSET), a two-week NASA funded workshop. This workshop focused on providing area teachers with a rigorous two-week experience loaded with interactive content lessons combined with hands-on activities, all relating to the universal laws of astronomy as well as solar system concepts.The effectiveness of this workshop was gauged in part through a series of content surveys given to each participating educator at the beginning and end of the workshop. Similar content surveys were also administered to each teacher's students as pre/post-content surveys in an effort to determine the extent to which teacher gains were transferred into student gains, as well as to judge the effectiveness of the teachers' lessons in conveying these concepts to the students.Overall, students performed best on concepts where teachers exhibited the highest gains in their learning and focused most of their emphasis. A question-by-question analysis, though, suggests that a broad analysis paints an incomplete picture of student learning. We will present an item analysis of student gains by topic along with a comparison of content coverage and teacher gains. Looking beyond these numbers will present results that demonstrate that giving secondary teachers professional development opportunities to increase content knowledge, and tools to present such knowledge to their students, can improve student learning and performance, but is dependent on teacher confidence and level of coverage.This project is supported by the NASA Science Mission Directorate Education and Public Outreach for Earth and Space Science (EPOESS), which is part of the Research Opportunities in Space and Earth Sciences (ROSES), Grant Number NNX12AH11G.

  18. Capital gains in economic theory and national accounting

    Directory of Open Access Journals (Sweden)

    J. STEINDL

    1998-12-01

    Full Text Available Capital gains are ironically one of the least studied concepts in economics despite their crucial role in national accounting. Although capital gains are technically not involved in the circular flow of production and incomes, they are a vital determinants of consumer credit and personal savings. Recent findings, in fact, correlate capital gains with the prevalence of inflationary pressures and gyrations on spending in assets.

  19. Rapid thermal annealing of phosphorus implanted silicon

    International Nuclear Information System (INIS)

    Lee, Y.H.; Pogany, A.; Harrison, H.B.; Williams, J.S.

    1985-01-01

    Rapid thermal annealing (RTA) of phosphorus-implanted silicon has been investigated by four point probe, Van der Pauw methods and transmission electron microscopy. The results have been compared to furnace annealing. Experiments show that RTA, even at temperatures as low as 605 deg C, results in good electrical properties with little remnant damage and compares favourably with furnace annealing

  20. An Experiment on Wind Energy

    Science.gov (United States)

    Lombardo, Vincenzo; Fiordilino, Emilio; Gallitto, Aurelio Agliolo; Aglieco, Pasquale

    2012-01-01

    We discuss an experiment on wind energy performed with home-made apparatus. The experiment reproduces a laboratory windmill, which can pump water from a lower level to a higher one. By measuring the gain of the gravitational potential energy of the pumped water, one can determine the power extracted from the wind. The activity was carried out with…

  1. Adequacy of Prenatal Care and Gestational Weight Gain

    Science.gov (United States)

    Crandell, Jamie L.; Jones-Vessey, Kathleen

    2016-01-01

    Abstract Background: The goal of prenatal care is to maximize health outcomes for a woman and her fetus. We examined how prenatal care is associated with meeting the 2009 Institute of Medicine (IOM) guidelines for gestational weight gain. Sample: The study used deidentified birth certificate data supplied by the North Carolina State Center for Health Statistics. The sample included 197,354 women (≥18 years) who delivered singleton full-term infants in 2011 and 2012. Methods: A generalized multinomial model was used to identify how adequate prenatal care was associated with the odds of gaining excessive or insufficient weight during pregnancy according to the 2009 IOM guidelines. The model adjusted for prepregnancy body size, sociodemographic factors, and birth weight. Results: A total of 197,354 women (≥18 years) delivered singleton full-term infants. The odds ratio (OR) for excessive weight gain was 2.44 (95% CI 2.37–2.50) in overweight and 2.33 (95% CI 2.27–2.40) in obese women compared with normal weight women. The OR for insufficient weight gain was 1.15 (95% CI 1.09–1.22) for underweight and 1.34 (95% CI 1.30–1.39) for obese women compared with normal weight women. Prenatal care at the inadequate or intermediate levels was associated with insufficient weight gain (OR: 1.32, 95% CI 1.27–1.38; OR: 1.15, 95% CI 1.09–1.21, respectively) compared with adequate prenatal care. Women with inadequate care were less likely to gain excessive weight (OR: 0.88, 95% CI 0.86–0.91). Conclusions: Whereas prenatal care was effective for preventing insufficient weight gain regardless of prepregnancy body size, educational background, and racial/ethnic group, there were no indications that adequate prenatal care was associated with reduced risk for excessive gestational weight gain. Further research is needed to improve prenatal care programs for preventing excess weight gain. PMID:26741198

  2. Developmental Gains in Visuospatial Memory Predict Gains in Mathematics Achievement

    OpenAIRE

    Li, Yaoran; Geary, David C.

    2013-01-01

    Visuospatial competencies are related to performance in mathematical domains in adulthood, but are not consistently related to mathematics achievement in children. We confirmed the latter for first graders and demonstrated that children who show above average first-to-fifth grade gains in visuospatial memory have an advantage over other children in mathematics. The study involved the assessment of the mathematics and reading achievement of 177 children in kindergarten to fifth grade, inclusiv...

  3. COSY Control Status. First results with rapid prototyped man-machine interface for accelerator control

    Energy Technology Data Exchange (ETDEWEB)

    Hacker, U [Forschungszentrum Juelich, Postfach 1913, 52425 Juelich (Germany); Haberbosch, C [Forschungszentrum Juelich, Postfach 1913, 52425 Juelich (Germany); Henn, K [Forschungszentrum Juelich, Postfach 1913, 52425 Juelich (Germany); Weinert, A [Forschungszentrum Juelich, Postfach 1913, 52425 Juelich (Germany)

    1994-12-15

    The experience gained with the COSY Control System after a six month commissioning period followed by a six month production period will be presented. The COSY Control System runs approximately 300 VME and VXI target systems using a total of about 1000 CPUs, the systems are driven by the diskless operating environment RT/OS, hosted by eight workcells. Application software is implemented using Object-Orientated programming paradigms. All accelerator components become interface functions as instances of an abstract device model class. Methods defined here present an abstract picture of the accelerator giving immediate access to device states and parameters. Operator interaction is defined by building views and controllers for the model. Higher level functions, such as defining an acceleration cycle, are easily developed and modified with the accelerator connected on-line to the model. In the first year of COSY operation the object based approach for a control system, together with a rapid prototyped man-machine interface has brought to light the potential of new functions such as on-line, real time programming on a running system yielding high programming performance. The advantages of this approach have not been, until now, fully appreciated. ((orig.))

  4. Quantifying the mechanisms of domain gain in animal proteins.

    Science.gov (United States)

    Buljan, Marija; Frankish, Adam; Bateman, Alex

    2010-01-01

    Protein domains are protein regions that are shared among different proteins and are frequently functionally and structurally independent from the rest of the protein. Novel domain combinations have a major role in evolutionary innovation. However, the relative contributions of the different molecular mechanisms that underlie domain gains in animals are still unknown. By using animal gene phylogenies we were able to identify a set of high confidence domain gain events and by looking at their coding DNA investigate the causative mechanisms. Here we show that the major mechanism for gains of new domains in metazoan proteins is likely to be gene fusion through joining of exons from adjacent genes, possibly mediated by non-allelic homologous recombination. Retroposition and insertion of exons into ancestral introns through intronic recombination are, in contrast to previous expectations, only minor contributors to domain gains and have accounted for less than 1% and 10% of high confidence domain gain events, respectively. Additionally, exonization of previously non-coding regions appears to be an important mechanism for addition of disordered segments to proteins. We observe that gene duplication has preceded domain gain in at least 80% of the gain events. The interplay of gene duplication and domain gain demonstrates an important mechanism for fast neofunctionalization of genes.

  5. Effects of having a baby on weight gain.

    Science.gov (United States)

    Brown, Wendy J; Hockey, Richard; Dobson, Annette J

    2010-02-01

    Women often blame weight gain in early adulthood on having a baby. The aim was to estimate the weight gain attributable to having a baby, after disentangling the effects of other factors that influence weight change at this life stage. A longitudinal study of a randomly selected cohort of 6458 Australian women, aged 18-23 years in 1996, was conducted. Self-report mailed surveys were completed in 1996, 2000, 2003, and 2006, and data were analyzed in 2008. On average, women gained weight at the rate of 0.93% per year (95% CI=0.89, 0.98) or 605 g/year (95% CI=580, 635) for a 65-kg woman. Over the 10-year study period, partnered women with one baby gained almost 4 kg more, and those with a partner but no baby gained 1.8 kg more, than unpartnered childless women (after adjustment for other significant factors: initial BMI and age; physical activity, sitting time, energy intake (2003); education level, hours in paid work, and smoking). Having a baby has a marked effect on 10-year weight gain, but there is also an effect attributable to getting married or living with a partner. Social and lifestyle as well as energy balance variables should be considered when developing strategies to prevent weight gain in young adult women. Copyright 2010 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  6. Temporal Gain Correction for X-Ray Calorimeter Spectrometers

    Science.gov (United States)

    Porter, F. S.; Chiao, M. P.; Eckart, M. E.; Fujimoto, R.; Ishisaki, Y.; Kelley, R. L.; Kilbourne, C. A.; Leutenegger, M. A.; McCammon, D.; Mitsuda, K.

    2016-01-01

    Calorimetric X-ray detectors are very sensitive to their environment. The boundary conditions can have a profound effect on the gain including heat sink temperature, the local radiation temperature, bias, and the temperature of the readout electronics. Any variation in the boundary conditions can cause temporal variations in the gain of the detector and compromise both the energy scale and the resolving power of the spectrometer. Most production X-ray calorimeter spectrometers, both on the ground and in space, have some means of tracking the gain as a function of time, often using a calibration spectral line. For small gain changes, a linear stretch correction is often sufficient. However, the detectors are intrinsically non-linear and often the event analysis, i.e., shaping, optimal filters etc., add additional non-linearity. Thus for large gain variations or when the best possible precision is required, a linear stretch correction is not sufficient. Here, we discuss a new correction technique based on non-linear interpolation of the energy-scale functions. Using Astro-HSXS calibration data, we demonstrate that the correction can recover the X-ray energy to better than 1 part in 104 over the entire spectral band to above 12 keV even for large-scale gain variations. This method will be used to correct any temporal drift of the on-orbit per-pixel gain using on-board calibration sources for the SXS instrument on the Astro-H observatory.

  7. Assessment of learning gains in a flipped biochemistry classroom.

    Science.gov (United States)

    Ojennus, Deanna Dahlke

    2016-01-01

    The flipped classroom has become an increasingly popular pedagogical approach to teaching and learning. In this study, learning gains were assessed in a flipped biochemistry course and compared to gains in a traditional lecture. Although measured learning gains were not significantly different between the two courses, student perception of learning gains did differ and indicates a higher level of satisfaction with the flipped lecture format. © 2015 The International Union of Biochemistry and Molecular Biology.

  8. Ultra-high gain diffusion-driven organic transistor

    Science.gov (United States)

    Torricelli, Fabrizio; Colalongo, Luigi; Raiteri, Daniele; Kovács-Vajna, Zsolt Miklós; Cantatore, Eugenio

    2016-01-01

    Emerging large-area technologies based on organic transistors are enabling the fabrication of low-cost flexible circuits, smart sensors and biomedical devices. High-gain transistors are essential for the development of large-scale circuit integration, high-sensitivity sensors and signal amplification in sensing systems. Unfortunately, organic field-effect transistors show limited gain, usually of the order of tens, because of the large contact resistance and channel-length modulation. Here we show a new organic field-effect transistor architecture with a gain larger than 700. This is the highest gain ever reported for organic field-effect transistors. In the proposed organic field-effect transistor, the charge injection and extraction at the metal–semiconductor contacts are driven by the charge diffusion. The ideal conditions of ohmic contacts with negligible contact resistance and flat current saturation are demonstrated. The approach is general and can be extended to any thin-film technology opening unprecedented opportunities for the development of high-performance flexible electronics. PMID:26829567

  9. Renyi information gain on quantum key

    International Nuclear Information System (INIS)

    Brandt, Howard E

    2007-01-01

    The concept of maximum Renyi information gain from quantum key is important in eavesdropping and security analyses of quantum key distribution. It is particularly useful in the design optimization of eavesdropping probes. The present work reviews the quantitative measure of Renyi information gain, its optimization, and application to the design of eavesdropping probes in which single-photon probe states become optimally entangled with the signal states on their way between the legitimate transmitter and receiver

  10. Small Satellite Mechanical Design Experience

    OpenAIRE

    Meyers, Stewart

    1993-01-01

    The design approach used and the experience gained in the building of four small satellite payloads is explained. Specific recommendations are made and the lessons learned on the SAMPEX program are detailed.

  11. Pump-beam-instability limits to Raman-gain-doublet ''fast-light'' pulse propagation

    International Nuclear Information System (INIS)

    Stenner, Michael D.; Gauthier, Daniel J.

    2003-01-01

    We investigate the behavior of a system for generating ''fast-light'' pulses in which a bichromatic Raman pumping beam is used to generate optical gain at two frequencies and a region of anomalous dispersion between them. It is expected that increasing the gain will increase the pulse advancement. However, as the gain increases, the pumping field becomes increasingly distorted, effectively limiting the pulse advancement. We observe as much as 12% of the input pump power converted to orthogonal polarization, broadening of the initially bichromatic pump field (25 MHz initial frequency separation) to more than 2.5 GHz, and a temporal collapse of the pump beam into an erratic train of sub-500-ps pulses. The instability is attributed to the combined effects of the cross modulation instability and stimulated Raman scattering. Extreme distortion of an injected pulse that should (absent the instability) experience an advancement of 21% of its width is observed. We conclude that the fast-light pulse advancement is limited to just a few percent of the pulse width using this pulse advancement technique. The limitation imposed by the instability is important because careful study of the information velocity in fast-light pulses requires that pulse advancement be large enough to distinguish the velocities of different pulse features. Possible methods for achieving pulse advancement by avoiding the distortion caused by the instability are discussed

  12. An approach for evaluating the repeatability of rapid wetland assessment methods: The effects of training and experience

    Science.gov (United States)

    We sampled 92 wetlands from four different basins in the United States to quantify observer repeatability in rapid wetland condition assessment using the Delaware Rapid Assessment Protocol (DERAP). In the Inland Bays basin of Delaware, 58 wetland sites were sampled by multiple ob...

  13. Cupriavidus necator JMP134 rapidly reduces furfural with a Zn-dependent alcohol dehydrogenase.

    Science.gov (United States)

    Li, Qunrui; Metthew Lam, L K; Xun, Luying

    2011-11-01

    Ethanol is a renewable biofuel, and it can be produced from lignocellulosic biomass. The biomass is usually converted to hydrolysates that consist of sugar and sugar derivatives, such as furfural. Yeast ferments sugar to ethanol, but furfural higher than 3 mM is inhibitory. It can take several days for yeast cells to reduce furfural to non-inhibitory furfuryl alcohol before producing ethanol. Bioreduction of furfural to furfuryl alcohol before fermentation may relieve yeast from furfural toxicity. We observed that Cupriavidus necator JMP134, a strict aerobe, rapidly reduced 17 mM furfural to less than 3 mM within 14 min with cell turbidity of 1.0 at 600 nm at 50°C. The rapid reduction consumed ethanol. The "furfural reductase" (FurX) was purified, and it oxidized ethanol to acetaldehyde and reduced furfural to furfuryl alcohol with NAD(+) as the cofactor. The protein was identified with mass spectrometry fingerprinting to be a hypothetical protein belonging to Zn-dependent alcohol dehydrogenase family. The furX-inactivation mutant of C. necator JMP134 lost the ability to rapidly reduce furfural, and Escherichia coli producing recombinant FurX gained the ability. Thus, an alcohol dehydrogenase enabled bacteria to rapidly reduce furfural with ethanol as the reducing power.

  14. Evidence-based medicine in rapidly changing technologies

    DEFF Research Database (Denmark)

    Schroeder, Torben Veith

    2008-01-01

    Evidence-based medicine (EBM) is not a randomised controlled trial (RCT), but EBM seeks to apply evidence gained from scientific methods - which could be RCT - to daily medical practice. Any surgical treatment reflects a certain development technically as well as skills based. The procedure may....... Special considerations should be given in rapidly developing fields. If started too early the resulting comparison will likely turn out to be irrelevant because the new technology is not fully developed, not mastered or the device may have undergone major modifications rendering the results obsolete....... On the other hand, if started too late there is a chance that data may be lost because the technology has already been introduced into the daily clinics and physicians may be unwilling to recruit patients. Or the opposite, that the technique may have been rejected without a proper trial. In this situation...

  15. DNA gains at 8q23.2

    DEFF Research Database (Denmark)

    da Silva Veiga, Luciana Caricati; Bérgamo, Nádia Aparecida; dos Reis, Patrícia Pintor

    2003-01-01

    Gains or amplifications involving chromosome arm 8q are one of the most recurrent chromosomal alterations in head and neck tumors. To characterize previously reported gains, we performed fluorescence in situ hybridization (FISH) using the sequences BAC RP1179E1 and 8-centromere PMJ 128 as probes....

  16. Experience with technology dynamics of user experience with mobile media devices

    CERN Document Server

    al-Azzawi, Ali

    2013-01-01

    With a focus on gaining an empirically derived understanding of the underlying psychological dimensions and processes behind people’s experiences with technology, this book contributes to the debate of user experience (UX) within several disciplines, including HCI, design and marketing. It analyses UX dynamics at various time scales, and explores the very nature of time and meaning in the context of UX.Experience with Technology uses personal construct theory (PCT) as a theoretical and methodological starting point to this project. Major case-studies are described that examine people’s exp

  17. Rapid analysis and exploration of fluorescence microscopy images.

    Science.gov (United States)

    Pavie, Benjamin; Rajaram, Satwik; Ouyang, Austin; Altschuler, Jason M; Steininger, Robert J; Wu, Lani F; Altschuler, Steven J

    2014-03-19

    Despite rapid advances in high-throughput microscopy, quantitative image-based assays still pose significant challenges. While a variety of specialized image analysis tools are available, most traditional image-analysis-based workflows have steep learning curves (for fine tuning of analysis parameters) and result in long turnaround times between imaging and analysis. In particular, cell segmentation, the process of identifying individual cells in an image, is a major bottleneck in this regard. Here we present an alternate, cell-segmentation-free workflow based on PhenoRipper, an open-source software platform designed for the rapid analysis and exploration of microscopy images. The pipeline presented here is optimized for immunofluorescence microscopy images of cell cultures and requires minimal user intervention. Within half an hour, PhenoRipper can analyze data from a typical 96-well experiment and generate image profiles. Users can then visually explore their data, perform quality control on their experiment, ensure response to perturbations and check reproducibility of replicates. This facilitates a rapid feedback cycle between analysis and experiment, which is crucial during assay optimization. This protocol is useful not just as a first pass analysis for quality control, but also may be used as an end-to-end solution, especially for screening. The workflow described here scales to large data sets such as those generated by high-throughput screens, and has been shown to group experimental conditions by phenotype accurately over a wide range of biological systems. The PhenoBrowser interface provides an intuitive framework to explore the phenotypic space and relate image properties to biological annotations. Taken together, the protocol described here will lower the barriers to adopting quantitative analysis of image based screens.

  18. Gain maximization in a probabilistic entanglement protocol

    Science.gov (United States)

    di Lorenzo, Antonio; Esteves de Queiroz, Johnny Hebert

    Entanglement is a resource. We can therefore define gain as a monotonic function of entanglement G (E) . If a pair with entanglement E is produced with probability P, the net gain is N = PG (E) - (1 - P) C , where C is the cost of a failed attempt. We study a protocol where a pair of quantum systems is produced in a maximally entangled state ρm with probability Pm, while it is produced in a partially entangled state ρp with the complementary probability 1 -Pm . We mix a fraction w of the partially entangled pairs with the maximally entangled ones, i.e. we take the state to be ρ = (ρm + wUlocρpUloc+) / (1 + w) , where Uloc is an appropriate unitary local operation designed to maximize the entanglement of ρ. This procedure on one hand reduces the entanglement E, and hence the gain, but on the other hand it increases the probability of success to P =Pm + w (1 -Pm) , therefore the net gain N may increase. There may be hence, a priori, an optimal value for w, the fraction of failed attempts that we mix in. We show that, in the hypothesis of a linear gain G (E) = E , even assuming a vanishing cost C -> 0 , the net gain N is increasing with w, therefore the best strategy is to always mix the partially entangled states. Work supported by CNPq, Conselho Nacional de Desenvolvimento Científico e Tecnológico, proc. 311288/2014-6, and by FAPEMIG, Fundação de Amparo à Pesquisa de Minas Gerais, proc. IC-FAPEMIG2016-0269 and PPM-00607-16.

  19. L2-gain and passivity techniques in nonlinear control

    CERN Document Server

    van der Schaft, Arjan

    2017-01-01

    This standard text gives a unified treatment of passivity and L2-gain theory for nonlinear state space systems, preceded by a compact treatment of classical passivity and small-gain theorems for nonlinear input-output maps. The synthesis between passivity and L2-gain theory is provided by the theory of dissipative systems. Specifically, the small-gain and passivity theorems and their implications for nonlinear stability and stabilization are discussed from this standpoint. The connection between L2-gain and passivity via scattering is detailed. Feedback equivalence to a passive system and resulting stabilization strategies are discussed. The passivity concepts are enriched by a generalised Hamiltonian formalism, emphasising the close relations with physical modeling and control by interconnection, and leading to novel control methodologies going beyond passivity. The potential of L2-gain techniques in nonlinear control, including a theory of all-pass factorizations of nonlinear systems, and of parametrization...

  20. Unconventional modes in lasers with spatially varying gain and loss

    International Nuclear Information System (INIS)

    Ge Li; Tuereci, H. E.; Chong, Y. D.; Stone, A. D.; Rotter, S.

    2011-01-01

    We discuss a class of lasing modes created by a spatially inhomogeneous gain profile. These lasing modes are ''extra modes,'' in addition to, and very different from, conventional lasing modes, which arise from the passive cavity resonances. These new modes do not have high intensity across the entire gain region, but instead are localized at the gain boundary and throughout the gain-free region. They are surface modes, originating from the transmission resonances of the gain-free region. Using an S-matrix description we connect these surface modes to the lasing modes in PT-symmetric (balanced gain-loss) cavities.

  1. Maternal Obesity, Gestational Weight Gain, and Asthma in Offspring.

    Science.gov (United States)

    Polinski, Kristen J; Liu, Jihong; Boghossian, Nansi S; McLain, Alexander C

    2017-11-09

    Obesity is common among women of childbearing age; intrauterine exposure to maternal obesity or gestational weight gain may influence the development of asthma in early childhood. We examined the relationships of maternal obesity and gestational weight gain with asthma in offspring. We used data from the Early Childhood Longitudinal Study-Birth Cohort, which has a nationally representative sample of children followed from birth in 2001 through age 4 (n = 6,450). Asthma was based on parental report of a medical professional's diagnosis. We used generalized estimating equation binomial models to compute adjusted odds ratios (ORs) of childhood asthma with maternal obesity and 4 measures of gestational weight gain. Compared with children of normal-weight mothers, children of obese mothers had increased risk of asthma (adjusted OR, 1.63; 95% confidence interval [CI], 1.26-2.12) by age 4, and children born to overweight mothers had similar risk (adjusted OR, 1.25; 95% CI, 0.99-1.59). Extreme-low weight gain (gain (≥25 kg) were associated with increased risk of asthma; however, the following measures were not significant predictors of asthma: meeting gestational weight gain recommendations of the Institute of Medicine, total gestational weight gain, and weekly rate of weight gain in the second and third trimesters. Extreme-low or extreme-high gestational weight gain and maternal obesity are risk factors for early childhood asthma, further evidence of the long-term impact of intrauterine exposure on children and the need to target preconception care to improve child health indicators.

  2. Rapid-Cycling Bubble-Chamber, details

    CERN Multimedia

    CERN PhotoLab

    1980-01-01

    Parts of the hydraulic expansion system of the Rapid-Cycling Bubble-Chamber (RCBC). RCBC was the largest of 3 rapid-cycling bubble-chambers (the others were LEBC and HOLEBC), used as target- and vertex-detectors within the European Hybrid Spectrometer (EHS) in the SPS North Area (EHN1). RCBC contained 250 l of liquid hydrogen and was located inside a 3 T superconducting magnet. It was designed for 30 expansions/s (100 times faster than BEBC), the system shown here allowed 50 expansions/s. RCBC operated from 1981 to 1983 for experiments NA21, NA22 and NA23 at a rate of 15 expansions/s, clocking up a total of over 4 million. In the rear, at left, is bearded Lucien Veillet; Augustin Didona is at the right. See also 8001009. The installation of the piston assembly in the RCBC chamber body is shown in the Annual Report 1980, p.65.

  3. TCAD simulation of Low Gain Avalanche Detectors

    Science.gov (United States)

    Dalal, Ranjeet; Jain, Geetika; Bhardwaj, Ashutosh; Ranjan, Kirti

    2016-11-01

    In the present work, detailed simulation using Technology Computer Aided Design (TCAD) tool, Silvaco for non-irradiated and irradiated LGAD (Low Gain Avalanche Detector) devices has been carried out. The effects of different design parameters and proton irradiation on LGAD operation are discussed in detail. An already published effective two trap bulk damage model is used to simulate the radiation damage without implementing any acceptor removal term. The TCAD simulation for irradiated LGAD devices produce decreasing gain with increasing fluence, similar to the measurement results. The space charge density and electric field distribution are used to illustrate the possible reasons for the degradation of gain of the irradiated LGAD devices.

  4. TCAD simulation of Low Gain Avalanche Detectors

    Energy Technology Data Exchange (ETDEWEB)

    Dalal, Ranjeet; Jain, Geetika; Bhardwaj, Ashutosh, E-mail: ashutosh.bhardwaj@cern.ch; Ranjan, Kirti

    2016-11-11

    In the present work, detailed simulation using Technology Computer Aided Design (TCAD) tool, Silvaco for non-irradiated and irradiated LGAD (Low Gain Avalanche Detector) devices has been carried out. The effects of different design parameters and proton irradiation on LGAD operation are discussed in detail. An already published effective two trap bulk damage model is used to simulate the radiation damage without implementing any acceptor removal term. The TCAD simulation for irradiated LGAD devices produce decreasing gain with increasing fluence, similar to the measurement results. The space charge density and electric field distribution are used to illustrate the possible reasons for the degradation of gain of the irradiated LGAD devices.

  5. TCAD simulation of Low Gain Avalanche Detectors

    International Nuclear Information System (INIS)

    Dalal, Ranjeet; Jain, Geetika; Bhardwaj, Ashutosh; Ranjan, Kirti

    2016-01-01

    In the present work, detailed simulation using Technology Computer Aided Design (TCAD) tool, Silvaco for non-irradiated and irradiated LGAD (Low Gain Avalanche Detector) devices has been carried out. The effects of different design parameters and proton irradiation on LGAD operation are discussed in detail. An already published effective two trap bulk damage model is used to simulate the radiation damage without implementing any acceptor removal term. The TCAD simulation for irradiated LGAD devices produce decreasing gain with increasing fluence, similar to the measurement results. The space charge density and electric field distribution are used to illustrate the possible reasons for the degradation of gain of the irradiated LGAD devices.

  6. Gain tuning and fidelity in continuous-variable quantum teleportation

    International Nuclear Information System (INIS)

    Ide, Toshiki; Hofmann, Holger F.; Furusawa, Akira; Kobayashi, Takayoshi

    2002-01-01

    The fidelity of continuous-variable teleportation can be optimized by changing the gain in the modulation of the output field. We discuss the gain dependence of fidelity for coherent, vacuum, and one-photon inputs and propose optimal gain tuning strategies for corresponding input selections

  7. Undergraduates' Perceived Gains and Ideas about Teaching and Learning Science from Participating in Science Education Outreach Programs

    Science.gov (United States)

    Carpenter, Stacey L.

    2015-01-01

    This study examined what undergraduate students gain and the ideas about science teaching and learning they develop from participating in K-12 science education outreach programs. Eleven undergraduates from seven outreach programs were interviewed individually about their experiences with outreach and what they learned about science teaching and…

  8. Energy Gaining Windows for Residental Buildings

    DEFF Research Database (Denmark)

    Kragh, Jesper; Laustsen, Jacob Birck; Svendsen, Svend

    2008-01-01

    window is made of fiber-reinforced plastic (plastic reinforced by fine fibers made of glass). This composite material is a weatherproof material with very low thermal conductivity and high mechanical strength. These properties make the material very suitable for frame profiles due to lower heat loss...... minus the heat loss integrated over the heating season. It is assumed that in northern cold climates all of the solar gain during the heating season can be utilized for space heating. Problems with overheating in the summer period must be solved with overhang or moveable solar shading devices. Two...... and longer durability of the window. The glazing in these fiber reinforced polyester windows is both unsealed and sealed triple glazing units. To increase the net energy gain slim frame profiles have been developed to increase the glazing area and thereby the solar gain. The challenge when developing slim...

  9. Advances in developing rapid, reliable and portable detection systems for alcohol.

    Science.gov (United States)

    Thungon, Phurpa Dema; Kakoti, Ankana; Ngashangva, Lightson; Goswami, Pranab

    2017-11-15

    Development of portable, reliable, sensitive, simple, and inexpensive detection system for alcohol has been an instinctive demand not only in traditional brewing, pharmaceutical, food and clinical industries but also in rapidly growing alcohol based fuel industries. Highly sensitive, selective, and reliable alcohol detections are currently amenable typically through the sophisticated instrument based analyses confined mostly to the state-of-art analytical laboratory facilities. With the growing demand of rapid and reliable alcohol detection systems, an all-round attempt has been made over the past decade encompassing various disciplines from basic and engineering sciences. Of late, the research for developing small-scale portable alcohol detection system has been accelerated with the advent of emerging miniaturization techniques, advanced materials and sensing platforms such as lab-on-chip, lab-on-CD, lab-on-paper etc. With these new inter-disciplinary approaches along with the support from the parallel knowledge growth on rapid detection systems being pursued for various targets, the progress on translating the proof-of-concepts to commercially viable and environment friendly portable alcohol detection systems is gaining pace. Here, we summarize the progress made over the years on the alcohol detection systems, with a focus on recent advancement towards developing portable, simple and efficient alcohol sensors. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Sleeve Push Technique: A Novel Method of Space Gaining.

    Science.gov (United States)

    Verma, Sanjeev; Bhupali, Nameksh Raj; Gupta, Deepak Kumar; Singh, Sombir; Singh, Satinder Pal

    2018-01-01

    Space gaining is frequently required in orthodontics. Multiple loops were initially used for space gaining and alignment. The most common used mechanics for space gaining is the use of nickel-titanium open coil springs. The disadvantage of nickel-titanium coil spring is that they cannot be used until the arches are well aligned to receive the stiffer stainless steel wires. Therefore, a new method of gaining space during initial alignment and leveling has been developed and named as sleeve push technique (SPT). The nickel-titanium wires, i.e. 0.012 inches and 0.014 inches along with archwire sleeve (protective tubing) can be used in a modified way to gain space along with alignment. This method helps in gaining space right from day 1 of treatment. The archwire sleeve and nickel-titanium wire in this new SPT act as a mutually synergistic combination and provide the orthodontist with a completely new technique for space opening.

  11. Sleeve push technique: A novel method of space gaining

    Directory of Open Access Journals (Sweden)

    Sanjeev Verma

    2018-01-01

    Full Text Available Space gaining is frequently required in orthodontics. Multiple loops were initially used for space gaining and alignment. The most common used mechanics for space gaining is the use of nickel–titanium open coil springs. The disadvantage of nickel–titanium coil spring is that they cannot be used until the arches are well aligned to receive the stiffer stainless steel wires. Therefore, a new method of gaining space during initial alignment and leveling has been developed and named as sleeve push technique (SPT. The nickel–titanium wires, i.e. 0.012 inches and 0.014 inches along with archwire sleeve (protective tubing can be used in a modified way to gain space along with alignment. This method helps in gaining space right from day 1 of treatment. The archwire sleeve and nickel–titanium wire in this new SPT act as a mutually synergistic combination and provide the orthodontist with a completely new technique for space opening.

  12. Development of a 3D FEL code for the simulation of a high-gain harmonic generation experiment

    International Nuclear Information System (INIS)

    Biedron, S. G.

    1999-01-01

    Over the last few years, there has been a growing interest in self-amplified spontaneous emission (SASE) free-electron lasers (FELs) as a means for achieving a fourth-generation light source. In order to correctly and easily simulate the many configurations that have been suggested, such as multi-segmented wigglers and the method of high-gain harmonic generation, we have developed a robust three-dimensional code. The specifics of the code, the comparison to the linear theory as well as future plans will be presented

  13. Assessment of Learning Gains in a Flipped Biochemistry Classroom

    Science.gov (United States)

    Ojennus, Deanna Dahlke

    2016-01-01

    The flipped classroom has become an increasingly popular pedagogical approach to teaching and learning. In this study, learning gains were assessed in a flipped biochemistry course and compared to gains in a traditional lecture. Although measured learning gains were not significantly different between the two courses, student perception of…

  14. Stimulated Raman gain scattering in thin planar dielectric waveguides

    NARCIS (Netherlands)

    Kanger, Johannes S.; Otto, Cornelis; Greve, Jan

    1995-01-01

    The stimulated Raman gain effect in planar dielectric waveguides is analyzed for the study of thin layers. Calculations show high gain factors and predict the possibility of detecting monolayers. Compared with those for methods based on ref lection, the gain can be 4 orders of magnitude higher for a

  15. Limitations of Experiments in Education Research

    Science.gov (United States)

    Schanzenbach, Diane Whitmore

    2012-01-01

    Research based on randomized experiments (along with high-quality quasi-experiments) has gained traction in education circles in recent years. There is little doubt this has been driven in large part by the shift in research funding strategy by the Department of Education's Institute of Education Sciences under Grover Whitehurst's lead, described…

  16. It is Time to Ban Rapid Weight Loss from Combat Sports.

    Science.gov (United States)

    Artioli, Guilherme G; Saunders, Bryan; Iglesias, Rodrigo T; Franchini, Emerson

    2016-11-01

    Most competitions in combat sports are divided into weight classes, theoretically allowing for fairer and more evenly contested disputes between athletes of similar body size, strength and agility. It has been well documented that most athletes, regardless of the combat sports discipline, reduce significant amounts of body weight in the days prior to competition to qualify for lighter weight classes. Rapid weight loss is characterised by the reduction of a significant amount of body weight (typically 2-10 %, although larger reductions are often seen) in a few days prior to weigh-in (mostly in the last 2-3 days) achieved by a combination of methods that include starvation, severe restriction of fluid intake and intentional sweating. In doing so, athletes try to gain a competitive advantage against lighter, smaller and weaker opponents. Such a drastic and rapid weight reduction is only achievable via a combination of aggressive strategies that lead to hypohydration and starvation. The negative impact of these procedures on health is well described in the literature. Although the impact of rapid weight loss on performance is debated, there remains robust evidence showing that rapid weight loss may not impair performance, and translates into an actual competitive advantage. In addition to the health and performance implications, rapid weight loss clearly breaches fair play and stands against the spirit of the sport because an athlete unwilling to compete having rapidly reduced weight would face unfair contests against opponents who are 'artificially' bigger and stronger. The World Anti-Doping Agency Code states that a prohibited method must meet at least two of the following criteria: (1) enhances performance; (2) endangers an athlete's health; and (3) violates the spirit of the sport. We herein argue that rapid weight loss clearly meets all three criteria and, therefore, should be banned from the sport. To quote the World Anti-Doping Agency Code, this would "protect

  17. Maximizing gain in high-throughput screening using conformal prediction.

    Science.gov (United States)

    Svensson, Fredrik; Afzal, Avid M; Norinder, Ulf; Bender, Andreas

    2018-02-21

    Iterative screening has emerged as a promising approach to increase the efficiency of screening campaigns compared to traditional high throughput approaches. By learning from a subset of the compound library, inferences on what compounds to screen next can be made by predictive models, resulting in more efficient screening. One way to evaluate screening is to consider the cost of screening compared to the gain associated with finding an active compound. In this work, we introduce a conformal predictor coupled with a gain-cost function with the aim to maximise gain in iterative screening. Using this setup we were able to show that by evaluating the predictions on the training data, very accurate predictions on what settings will produce the highest gain on the test data can be made. We evaluate the approach on 12 bioactivity datasets from PubChem training the models using 20% of the data. Depending on the settings of the gain-cost function, the settings generating the maximum gain were accurately identified in 8-10 out of the 12 datasets. Broadly, our approach can predict what strategy generates the highest gain based on the results of the cost-gain evaluation: to screen the compounds predicted to be active, to screen all the remaining data, or not to screen any additional compounds. When the algorithm indicates that the predicted active compounds should be screened, our approach also indicates what confidence level to apply in order to maximize gain. Hence, our approach facilitates decision-making and allocation of the resources where they deliver the most value by indicating in advance the likely outcome of a screening campaign.

  18. Evaluating realized genetic gains from tree improvement.

    Science.gov (United States)

    J.B. St. Clair

    1993-01-01

    Tree improvement has become an essential part of the management of forest lands for wood production, and predicting yields and realized gains from forests planted with genetically-improved trees will become increasingly important. This paper discusses concepts of tree improvement and genetic gain important to growth and yield modeling, and reviews previous studies of...

  19. Rapid application development using the Tcl/Tk language

    International Nuclear Information System (INIS)

    van Zeijts, J.

    1995-01-01

    During the last year, high level applications at CEBAF were written using the Tcl/Tk scripting language. This language is rapidly gaining in popularity, in part due to ease of constructing programs with X11 graphical user interfaces, and in part to ease of adding compiled user code for specialized purposes. Extensions to the language provide object oriented programming, which was used to develop a hierarchy of classes relevant for high level accelerator control. We describe basic language features, some 3rd party add-on packages, and local additions to the toolbox. Next we describe features of the accelerator object hierarchy, and finally describe applications written using this toolbox such as the ModelServer prototype, Slow Orbit and Energy Lock, the Linac Energy Management System, and other applications

  20. Capital Gains Taxation and House Price Fluctuations

    DEFF Research Database (Denmark)

    Fuest, Clemens; Nielsen, Søren Bo

    2004-01-01

    Recent years have seen large swings in house prices in many countries. Motivated by housing price variations, proposals for taxing capital gains on housing have repeatedly been put forth. The idea seems to be that such taxes would curb the redistribution occurring between those owning houses...... and those trying to get into the market for owner-occupied housing. Our paper shows that at least in simple settings, a tax on real capital gains on housing will only lead to even bigger price swings and will not be able to redistribute between people appearing on either side of the housing market.......Keywords: capital gains tax, housing market, price fluctuationsJEL-Classification: H23, H24, R 31.Addresses:...

  1. Rapidity and multiplicity correlations in high energy hadronic collisions

    International Nuclear Information System (INIS)

    Heiselberg, H.

    1993-01-01

    Rapidity and multiplicity correlations of particle production in high energy hadronic collisions are studied. A simple model including short range correlations in rapidity due to clustering and long range correlations due to energy conservation is able to describe the two-body correlation functions well hadron-nucleon collisions around lab energies of 250 GeV. In this model fractional moments are calculated and compared to data. The strong rise of the factorial moments in rapidity intervals by size δy∝1 can be explained by long and short range correlation alone whereas the factorial moments approach a constant value at very small δy due to lack of correlations also in agreement with experiment. There is therefore no need for introducing intermittency in the particle production in hadronic collisions at these energies. (orig.)

  2. 46 CFR 287.12 - Election as to nonrecognition of gain.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Election as to nonrecognition of gain. 287.12 Section... of gain. (a) Election requirements. As a prerequisite to the nonrecognition of gain on the sale or... partnership, in the partnership return of income) for the taxable year in which the gain with respect to the...

  3. Heliostat-field gain-scheduling control applied to a two-step solar hydrogen production plant

    International Nuclear Information System (INIS)

    Roca, Lidia; Calle, Alberto de la; Yebra, Luis J.

    2013-01-01

    Highlights: ► A control system is proposed for a solar reactor system which produces hydrogen. ► The controller chooses which heliostats from the solar field must be focused. ► A gain scheduling scheme is included to deal with different system dynamics. ► The scheme is tested and tunned in simulation. ► Real experiments show the promising results of this work. -- Abstract: This article describes a temperature control structure designed for the interior of a solar hydrogen reactor based on a two-step ferrite-redox technology. Until now, this temperature has been controlled by manual selection of the heliostats to be focused on the receiver targets. However, the strong system dependency on operating conditions suggests that the procedure be automated in order to ensure the desired setpoint change response. The aims are to maintain the desired temperatures and to make the setpoint switch as fast as possible, keeping plant conditions within the margins of safety. The scheme proposed includes a procedure for selecting the heliostats to be focused on the reactor by using a simple model of the solar field and a gain scheduling control system which changes the control tuning parameters to deal with the varying dynamics observed during the process. Real experiments show the promising results of this work.

  4. Variety Gains and the Extensive Margin of Trade

    OpenAIRE

    Mohler, Lukas

    2012-01-01

    Findings from the literature suggest that previous estimates of the variety gains from trade are too small because of the imprecise measurement of the imported variety set under the Armington assumption. In this contribution, I use results from the literature on multi-product firms to obtain variety gain estimates that account for the entry and exit of firms as well as for product turnover within firms and find that welfare gains increase by a factor of 2.5 compared to the baseline Armington ...

  5. 26 CFR 1.737-1 - Recognition of precontribution gain.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Recognition of precontribution gain. 1.737-1... gain. (a) Determination of gain—(1) In general. A partner that receives a distribution of property (other than money) must recognize gain under section 737 and this section in an amount equal to the...

  6. Optimizing beam transport in rapidly compressing beams on the neutralized drift compression experiment – II

    Directory of Open Access Journals (Sweden)

    Anton D. Stepanov

    2018-03-01

    Full Text Available The Neutralized Drift Compression Experiment-II (NDCX-II is an induction linac that generates intense pulses of 1.2 MeV helium ions for heating matter to extreme conditions. Here, we present recent results on optimizing beam transport. The NDCX-II beamline includes a 1-m-long drift section downstream of the last transport solenoid, which is filled with charge-neutralizing plasma that enables rapid longitudinal compression of an intense ion beam against space-charge forces. The transport section on NDCX-II consists of 28 solenoids. Finding optimal field settings for a group of solenoids requires knowledge of the envelope parameters of the beam. Imaging the beam on the scintillator gives the radius of the beam, but the envelope angle is not measured directly. We demonstrate how the parameters of the beam envelope (radius, envelop angle, and emittance can be reconstructed from a series of images taken by varying the B-field strengths of a solenoid upstream of the scintillator. We use this technique to evaluate emittance at several points in the NDCX-II beamline and for optimizing the trajectory of the beam at the entry of the plasma-filled drift section. Keywords: Charged-particle beams, Induction accelerators, Beam dynamics, Beam emittance, Ion beam diagnostics, PACS Codes: 41.75.-i, 41.85.Ja, 52.59.Sa, 52.59.Wd, 29.27.Eg

  7. Study of a large rapid ashing apparatus and a rapid dry ashing method for biological samples and its application

    International Nuclear Information System (INIS)

    Jin Meisun; Wang Benli; Liu Wencang

    1988-04-01

    A large rapid-dry-ashing apparatus and a rapid ashing method for biological samples are described. The apparatus consists of specially made ashing furnace, gas supply system and temperature-programming control cabinet. The following adventages have been showed by ashing experiment with the above apparatus: (1) high speed of ashing and saving of electric energy; (2) The apparatus can ash a large amount of samples at a time; (3) The ashed sample is pure white (or spotless), loose and easily soluble with few content of residual char; (4) The fresh sample can also be ashed directly. The apparatus is suitable for ashing a large amount of the environmental samples containing low level radioactivity trace elements and the medical, food and agricultural research samples

  8. 26 CFR 1.1247-3 - Treatment of capital gains.

    Science.gov (United States)

    2010-04-01

    ... portion of the excess capital gains were designated. The amount so includible by the partnership shall be... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Treatment of capital gains. 1.1247-3 Section 1... (CONTINUED) INCOME TAXES Special Rules for Determining Capital Gains and Losses § 1.1247-3 Treatment of...

  9. Comparing weight gain in the year prior to treatment for overweight and obese patients with and without binge eating disorder in primary care.

    Science.gov (United States)

    Ivezaj, Valentina; Kalebjian, Roushig; Grilo, Carlos M; Barnes, Rachel D

    2014-08-01

    To examine weight change trajectories among overweight and obese patients with binge eating disorder (BED) versus without (NBO) during the year prior to seeking treatment. Participants were 97 (75 women, 22 men) overweight and obese patients recruited for the same weight-loss treatment in primary care; 26 (27%) met DSM-5 BED criteria. Participants were assessed with the Eating Disorder Examination and completed self-report questionnaires about their weight histories and the Beck Depression Inventory-II. Participants' self-reported current weight and measured current weight were significantly correlated and did not statistically differ. Reported weight changes during the year prior to seeking treatment differed significantly by group: BED patients gained an average of 18.3lb (8.2kg) whereas NBO patients gained an average of 1.5lb (0.7kg). Among BED patients, but not NBO, weight change during the prior year was positively correlated with greater eating-disorder psychopathology, binge-eating frequency, frequency of overeating at lunch and dinner, and depression scores. For the overall group, BED status and binge-eating frequency each made independent significant contributions to predicting weight change in the past year. Findings suggest BED patients are gaining considerably more weight during the year prior to treatment than NBO patients. BED treatment may interrupt a steep weight gain trajectory and prevent further weight gain for BED patients suggesting need for early intervention. Primary care physicians should screen for BED when overweight and obese patients present with rapid weight gain. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Active metamaterial: Gain and stability, and microfluidic chip for THz cell spectroscopy

    Science.gov (United States)

    Tang, Qi

    Metamaterials are artificially designed composite materials which can exhibit unique and unusual properties such as the negative refractive index, negative phase velocity, etc. The concept of metamaterials becomes prevalent in the electromagnetic society since the first experimental implementation in the early 2000s. Many fascinated potential applications, e.g. super lens, invisibility cloaking, and novel antennas that are electrically small, have been proposed based on metamaterials. However, most of the applications still remain in theory and are not suitable for practical applications mainly due to the intrinsic loss and narrow bandwidth (large dispersion) determined by the fundamental physics of metamaterials. In this dissertation, we incorporate active gain devices into conventional passive metamaterials to overcome loss and even provide gain. Two types of active gain negative refractive index metamaterials are proposed, designed and experimentally demonstrated, including an active composite left-/right-handed transmission line and an active volumetric metamaterial. In addition, we investigate the non-Foster circuits for broadband matching of electrically small antennas. A rigorous way of analyzing the stability of non-Foster circuits by normalized determinant function is proposed. We study the practical factors that may affect the stability of non-Foster circuits, including the device parasitics, DC biasing, layouts and load impedance. A stable floating negative capacitor is designed, fabricated and tested. Moreover, it is important to resolve the sign of refractive index for active gain media which can be quite challenging. We investigate the analytical solution of a gain slab system, and apply the Nyquist criterion to analyze the stability of a causal gain medium. We then emphasize that the result of frequency domain simulation has to be treated with care. Lastly, this dissertation discusses another interesting topic about THz spectroscopy of live cells

  11. Exploring the diet and lifestyle changes contributing to weight gain among Australian West African women following migration: A qualitative study.

    Science.gov (United States)

    Babatunde-Sowole, Olutoyin O; Power, Tamara; Davidson, Patricia; Ballard, Charlotte; Jackson, Debra

    2018-04-10

    This paper reports on women's experiences of weight gain and obesity as they became acculturated to the Australian diet and lifestyle. Migrants from sub-Saharan Africa have a much higher risk of obesity than the native population when settling in industrialised countries. Qualitative. Women in this study reported weight gain post-migration. This was attributed to increased access to a wide variety of food including takeaway food and more sedentary lifestyles. Obesity has long-term consequences for health and well-being. Further research is needed to support a healthy transition to life in Australia. Gaining insight into the underlying reasons that West African immigrants to Australia become obese could contribute to assisting health professionals design culturally appropriate interventions and health education programmes to support new arrivals.

  12. Dissociation of rapid response learning and facilitation in perceptual and conceptual networks of person recognition.

    Science.gov (United States)

    Valt, Christian; Klein, Christoph; Boehm, Stephan G

    2015-08-01

    Repetition priming is a prominent example of non-declarative memory, and it increases the accuracy and speed of responses to repeatedly processed stimuli. Major long-hold memory theories posit that repetition priming results from facilitation within perceptual and conceptual networks for stimulus recognition and categorization. Stimuli can also be bound to particular responses, and it has recently been suggested that this rapid response learning, not network facilitation, provides a sound theory of priming of object recognition. Here, we addressed the relevance of network facilitation and rapid response learning for priming of person recognition with a view to advance general theories of priming. In four experiments, participants performed conceptual decisions like occupation or nationality judgments for famous faces. The magnitude of rapid response learning varied across experiments, and rapid response learning co-occurred and interacted with facilitation in perceptual and conceptual networks. These findings indicate that rapid response learning and facilitation in perceptual and conceptual networks are complementary rather than competing theories of priming. Thus, future memory theories need to incorporate both rapid response learning and network facilitation as individual facets of priming. © 2014 The British Psychological Society.

  13. Parametric Design and Rapid Prototyping of Installation Box for Vehicle Terminal PCB

    Directory of Open Access Journals (Sweden)

    Wang Xingxing

    2016-01-01

    Full Text Available Installation box for vehicle terminal PCB (Printed Circuit Board was took as research object, which is encountered in the process of project developing. Vehicle terminal PCB in actual development process was set as an example, point cloud data were acquired by three coordinate measuring method; Imageware software was used to reconstruct the vehicle terminal PCB model, basic size parameters of vehicle terminal PCB can be got and then design parameters of installation box for vehicle terminal PCB can be determined. Design of the installation box for vehicle terminal PCB was completed based on Solidworks software, then 3D modeling and 2D drawing of installation box for vehicle terminal PCB was gained. Up Plus 2 rapid prototype machine was used to manufacture installation box for vehicle terminal PCB rapidly based on 3D printing technology, then prototype of installation box for vehicle terminal PCB was obtained. It is of certain engineering significant for single (small amount manufacturing of installation box for general PCB.

  14. Rapid characterization of superconducting wires and tapes in strong pulsed magnetic fields

    International Nuclear Information System (INIS)

    Bockstal, L. van; Keyser, A. de; Deschagt, J.; Hopkins, S.C.; Glowacki, B.A.

    2007-01-01

    A new measurement system for rapid characterization of superconducting wires and tapes is developed. The CryoPulse-BI is a system to provide a direct measurement of critical material parameters for superconducting materials when high long pulsed magnetic fields and strong currents are applied. In the experiments, synchronized magnetic fields up to 30 T and current pulses up to 5 kA are generated with adjustable timing. Varying the magnetic field strength, the current through the sample and the BI timing allows for a thorough characterization of the sample and the determination of critical currents. The rapid cycle time of the experiments yields a rapid and thorough determination of the critical parameters. The method has been tested on low T c as well as high T c materials with the field parallel or perpendicular to the current. The discussion covers the current state of the art including a comparison of our results to classical DC characterization measurements

  15. SiPM Gain Stabilization Studies for Adaptive Power Supply

    CERN Document Server

    AUTHOR|(CDS)2074257; Zalieckas, Justas; Cvach, Jaroslav; Kvasnicka, Jiri; Polak, Ivo

    2016-01-01

    We present herein gain stabilization studies of SiPMs using a climate chamber at CERN. We present results for four detectors not tested before, three from Hamamatsu and one from KETEK. Two of the Hamamatsu SiPMs are novel sensors with trenches that reduce cross talk. We use an improved readout system with a digital oscilloscope controlled with a dedicated LabView program. We improved and automized the analysis to deal with large datasets. We have measured the gain-versus-bias-voltage dependence at fixed temperature and gain-versus-temperature dependence at fixed bias voltage to determine the bias voltage dependence on temperature $V(T)$ for stable gain. We show that the gain remains stable to better than $\\pm 0.5\\%$ in the $20^\\circ \\rm C - 30^\\circ C$ temperature range if the bias voltage is properly adjusted with temperature.

  16. LASL experience in decontamination of the environment

    International Nuclear Information System (INIS)

    Ahlquist, A.J.

    1979-01-01

    Since 1972 the Los Alamos Scientific Laboratory (LASL) has been actively involved in land area surveys for radioactive contamination and has gained considerable experience in cleanup of lands considered to have unacceptable levels of radioactive contamination. This paper describes our experience and means of arriving at recommendations for ALARA

  17. Polarization dependence of the optical modal gain in ZnO

    International Nuclear Information System (INIS)

    Kim, Bumjin; Kyhm, Kwangseuk; Cho, Chaeryong

    2010-01-01

    The modal gain spectrum due to the electron-hole plasma in ZnO was measured using a variable stripe length method. A modal gain contour map for energy and stripe length allowed the modal gain saturation to be analyzed in terms of the spectral and the stripe length dependences. The modal gain was observed to be more significant in the TE mode than in the TM mode due to the polarization asymmetry of the wurtzite structure. We also found that the degree of polarization are enhanced as the stripe length increased, despite of modal gain saturation.

  18. Time Difference Amplifier with Robust Gain Using Closed-Loop Control

    Science.gov (United States)

    Nakura, Toru; Mandai, Shingo; Ikeda, Makoto; Asada, Kunihiro

    This paper presents a Time Difference Amplifier (TDA) that amplifies the input time difference into the output time difference. Cross coupled chains of variable delay cells with the same number of stages are applicable for TDA, and the gain is adjusted via the closed-loop control. The TDA was fabricated using 65nm CMOS and the measurement results show that the time difference gain is 4.78 at a nominal power supply while the designed gain is 4.0. The gain is stable enough to be less than 1.4% gain shift under ±10% power supply voltage fluctuation.

  19. Gain beyond cosmesis: Demonstration of psychosocial and functional gains following successful strabismus surgery using the adult strabismus questionnaire adult strabismus 20

    Directory of Open Access Journals (Sweden)

    Danish Alam

    2014-01-01

    Full Text Available Background: Strabismus adversely affects psychosocial and functional aspects; while its correction impacts positively. Aim: The aim was to evaluate the gains in scores: Overall scores (OASs, psychosocial subscale scores (PSSs and functional subscale scores (FSSs following successful surgical alignment. Settings and Design: We evaluated changed scores in the adult strabismus 20 (AS-20 questionnaire, administered before and after successful surgery. Materials and Methods: Thirty adults horizontal strabismics, were administered the AS-20, at baseline, and at 6-week and 3-month. Group-wise analysis was carried out based on gender, strabismus type (esotropia [ET] or exotropia [XT], back-ground and amblyopia. Statistical Analysis: We used Wilcoxon, and Mann-Whitney U-tests. Significance was set at P ≤ 0.05. Results: At baseline, there were no significant differences within the groups, except that those with amblyopia significantly scored less than nonamblyopes in OAS (median scores: 53.8 vs. 71.3; P = 0.009 and FSS (56.3 vs. 85.3; P = 0.009. OAS, PSS and FSS showed significant gains at 6-week and 3-month (all Wilcoxon P < 0.001. Compared with males, females showed significantly more gain at 3-month (OAS: 37.9 vs. 28.7; P = 0.02, on account of PSS gain (49.6 vs. 37.5; P = 0.01. The ET performed better than XT only on the FSS at 6-week (28.7 vs. 15.0; P = 0.02. Vis-à-vis the nonamblyopes, the amblyopes showed significantly more benefit at 6-week alone (OAS: 18.7 vs. 28.7; P = 0.04, largely due to gains in PSS. Conclusions: Successful strabismus surgery has demonstrated significant gains in psychosocial, functional and overall functions. There is some evidence that gains may be more in females; with a trend to better outcomes in ET and amblyopes up to 6-week.

  20. A course-based research experience: how benefits change with increased investment in instructional time.

    Science.gov (United States)

    Shaffer, Christopher D; Alvarez, Consuelo J; Bednarski, April E; Dunbar, David; Goodman, Anya L; Reinke, Catherine; Rosenwald, Anne G; Wolyniak, Michael J; Bailey, Cheryl; Barnard, Daron; Bazinet, Christopher; Beach, Dale L; Bedard, James E J; Bhalla, Satish; Braverman, John; Burg, Martin; Chandrasekaran, Vidya; Chung, Hui-Min; Clase, Kari; Dejong, Randall J; Diangelo, Justin R; Du, Chunguang; Eckdahl, Todd T; Eisler, Heather; Emerson, Julia A; Frary, Amy; Frohlich, Donald; Gosser, Yuying; Govind, Shubha; Haberman, Adam; Hark, Amy T; Hauser, Charles; Hoogewerf, Arlene; Hoopes, Laura L M; Howell, Carina E; Johnson, Diana; Jones, Christopher J; Kadlec, Lisa; Kaehler, Marian; Silver Key, S Catherine; Kleinschmit, Adam; Kokan, Nighat P; Kopp, Olga; Kuleck, Gary; Leatherman, Judith; Lopilato, Jane; Mackinnon, Christy; Martinez-Cruzado, Juan Carlos; McNeil, Gerard; Mel, Stephanie; Mistry, Hemlata; Nagengast, Alexis; Overvoorde, Paul; Paetkau, Don W; Parrish, Susan; Peterson, Celeste N; Preuss, Mary; Reed, Laura K; Revie, Dennis; Robic, Srebrenka; Roecklein-Canfield, Jennifer; Rubin, Michael R; Saville, Kenneth; Schroeder, Stephanie; Sharif, Karim; Shaw, Mary; Skuse, Gary; Smith, Christopher D; Smith, Mary A; Smith, Sheryl T; Spana, Eric; Spratt, Mary; Sreenivasan, Aparna; Stamm, Joyce; Szauter, Paul; Thompson, Jeffrey S; Wawersik, Matthew; Youngblom, James; Zhou, Leming; Mardis, Elaine R; Buhler, Jeremy; Leung, Wilson; Lopatto, David; Elgin, Sarah C R

    2014-01-01

    There is widespread agreement that science, technology, engineering, and mathematics programs should provide undergraduates with research experience. Practical issues and limited resources, however, make this a challenge. We have developed a bioinformatics project that provides a course-based research experience for students at a diverse group of schools and offers the opportunity to tailor this experience to local curriculum and institution-specific student needs. We assessed both attitude and knowledge gains, looking for insights into how students respond given this wide range of curricular and institutional variables. While different approaches all appear to result in learning gains, we find that a significant investment of course time is required to enable students to show gains commensurate to a summer research experience. An alumni survey revealed that time spent on a research project is also a significant factor in the value former students assign to the experience one or more years later. We conclude: 1) implementation of a bioinformatics project within the biology curriculum provides a mechanism for successfully engaging large numbers of students in undergraduate research; 2) benefits to students are achievable at a wide variety of academic institutions; and 3) successful implementation of course-based research experiences requires significant investment of instructional time for students to gain full benefit.

  1. Storytelling tools in support of user experience design

    NARCIS (Netherlands)

    Peng, Qiong

    2017-01-01

    Storytelling has been proposed as an intuitive way to support communication in user experience design. With story-based thinking, designers can gain a better understanding of the potential user experience, developing and discussing design ideas within an (imagined) context. This proposal introduces

  2. Transformation in Graduates of Hakomi Therapy Training: A Mindful, Body-Centered Approach

    Science.gov (United States)

    Himanen, Caren

    2015-01-01

    Corrective experiences (CEs) in psychotherapy are important curative factors and clients who experience transformation post rapid gains and thrive as a result. Although transformations are important indicators of growth, less than half of clients experience them. This qualitative study explored the experience of transformation in graduates of a…

  3. Fast Estimation of Expected Information Gain for Bayesian Experimental Design Based on Laplace Approximation

    KAUST Repository

    Long, Quan; Scavino, Marco; Tempone, Raul; Wang, Suojin

    2014-01-01

    Shannon-type expected information gain is an important utility in evaluating the usefulness of a proposed experiment that involves uncertainty. Its estimation, however, cannot rely solely on Monte Carlo sampling methods, that are generally too computationally expensive for realistic physical models, especially for those involving the solution of stochastic partial differential equations. In this work we present a new methodology, based on the Laplace approximation of the posterior probability density function, to accelerate the estimation of expected information gain in the model parameters and predictive quantities of interest. Furthermore, in order to deal with the issue of dimensionality in a complex problem, we use sparse quadratures for the integration over the prior. We show the accuracy and efficiency of the proposed method via several nonlinear numerical examples, including a single parameter design of one dimensional cubic polynomial function and the current pattern for impedance tomography.

  4. Fast Estimation of Expected Information Gain for Bayesian Experimental Design Based on Laplace Approximation

    KAUST Repository

    Long, Quan

    2014-01-06

    Shannon-type expected information gain is an important utility in evaluating the usefulness of a proposed experiment that involves uncertainty. Its estimation, however, cannot rely solely on Monte Carlo sampling methods, that are generally too computationally expensive for realistic physical models, especially for those involving the solution of stochastic partial differential equations. In this work we present a new methodology, based on the Laplace approximation of the posterior probability density function, to accelerate the estimation of expected information gain in the model parameters and predictive quantities of interest. Furthermore, in order to deal with the issue of dimensionality in a complex problem, we use sparse quadratures for the integration over the prior. We show the accuracy and efficiency of the proposed method via several nonlinear numerical examples, including a single parameter design of one dimensional cubic polynomial function and the current pattern for impedance tomography.

  5. Weight Gain, Schizophrenia and Antipsychotics: New Findings from Animal Model and Pharmacogenomic Studies

    Directory of Open Access Journals (Sweden)

    Fabio Panariello

    2011-01-01

    Full Text Available Excess body weight is one of the most common physical health problems among patients with schizophrenia that increases the risk for many medical problems, including type 2 diabetes mellitus, coronary heart disease, osteoarthritis, and hypertension, and accounts in part for 20% shorter life expectancy than in general population. Among patients with severe mental illness, obesity can be attributed to an unhealthy lifestyle, personal genetic profile, as well as the effects of psychotropic medications, above all antipsychotic drugs. Novel “atypical” antipsychotic drugs represent a substantial improvement on older “typical” drugs. However, clinical experience has shown that some, but not all, of these drugs can induce substantial weight gain. Animal models of antipsychotic-related weight gain and animal transgenic models of knockout or overexpressed genes of antipsychotic receptors have been largely evaluated by scientific community for changes in obesity-related gene expression or phenotypes. Moreover, pharmacogenomic approaches have allowed to detect more than 300 possible candidate genes for antipsychotics-induced body weight gain. In this paper, we summarize current thinking on: (1 the role of polymorphisms in several candidate genes, (2 the possible roles of various neurotransmitters and neuropeptides in this adverse drug reaction, and (3 the state of development of animal models in this matter. We also outline major areas for future research.

  6. Low-Gain, Low-Noise Integrated Neuronal Amplifier for Implantable Artifact-Reduction Recording System

    Directory of Open Access Journals (Sweden)

    Abdelhamid Benazzouz

    2013-09-01

    Full Text Available Brain neuroprostheses for neuromodulation are being designed to monitor the neural activity of the brain in the vicinity of the region being stimulated using a single macro-electrode. Using a single macro-electrode, recent neuromodulation studies show that recording systems with a low gain neuronal amplifier and successive amplifier stages can reduce or reject stimulation artifacts. These systems were made with off-the-shelf components that are not amendable for future implant design. A low-gain, low-noise integrated neuronal amplifier (NA with the capability of recording local field potentials (LFP and spike activity is presented. In vitro and in vivo characterizations of the tissue/electrode interface, with equivalent impedance as an electrical model for recording in the LFP band using macro-electrodes for rodents, contribute to the NA design constraints. The NA occupies 0.15 mm2 and dissipates 6.73 µW, and was fabricated using a 0.35 µm CMOS process. Test-bench validation indicates that the NA provides a mid-band gain of 20 dB and achieves a low input-referred noise of 4 µVRMS. Ability of the NA to perform spike recording in test-bench experiments is presented. Additionally, an awake and freely moving rodent setup was used to illustrate the integrated NA ability to record LFPs, paving the pathway for future implantable systems for neuromodulation.

  7. College Freshmen Students' Perspectives on Weight Gain Prevention in the Digital Age: Web-Based Survey.

    Science.gov (United States)

    Monroe, Courtney M; Turner-McGrievy, Gabrielle; Larsen, Chelsea A; Magradey, Karen; Brandt, Heather M; Wilcox, Sara; Sundstrom, Beth; West, Delia Smith

    2017-10-12

    College freshmen are highly vulnerable to experiencing weight gain, and this phenomenon is associated with an increased risk of chronic diseases and mortality in older adulthood. Technology offers an attractive and scalable way to deliver behavioral weight gain prevention interventions for this population. Weight gain prevention programs that harness the appeal and widespread reach of Web-based technologies (electronic health or eHealth) are increasingly being evaluated in college students. Yet, few of these interventions are informed by college students' perspectives on weight gain prevention and related lifestyle behaviors. The objective of this study was to assess college freshmen students' concern about weight gain and associated topics, as well as their interest in and delivery medium preferences for eHealth programs focused on these topics. Web-based surveys that addressed college freshmen students' (convenience sample of N=50) perspectives on weight gain prevention were administered at the beginning and end of the fall 2015 semester as part of a longitudinal investigation of health-related issues and experiences in first semester college freshmen. Data on weight gain prevention-related concerns and corresponding interest in eHealth programs targeting topics of potential concern, as well as preferred program delivery medium and current technology use were gathered and analyzed using descriptive statistics. A considerable proportion of the freshmen sample expressed concern about weight gain (74%, 37/50) and both traditional (healthy diet: 86%, 43/50; physical activity: 64%, 32/50) and less frequently addressed (stress: 82%, 41/50; sleep: 74%, 37/50; anxiety and depression: 60%, 30/50) associated topics within the context of behavioral weight gain prevention. The proportion of students who reported interest in eHealth promotion programs targeting these topics was also generally high (ranging from 52% [26/50] for stress management to 70% [35/50] for eating a

  8. FEL small signal gain reduction due to phase error of undulator

    International Nuclear Information System (INIS)

    Jia Qika

    2002-01-01

    The effects of undulator phase errors on the Free Electron Laser small signal gain is analyzed and discussed. The gain reduction factor due to the phase error is given analytically for low-gain regimes, it shows that degradation of the gain is similar to that of the spontaneous radiation, has a simple exponential relation with square of the rms phase error, and the linear variation part of phase error induces the position shift of maximum gain. The result also shows that the Madey's theorem still hold in the presence of phase error. The gain reduction factor due to the phase error for high-gain regimes also can be given in a simple way

  9. Association of Group Prenatal Care With Gestational Weight Gain.

    Science.gov (United States)

    Kominiarek, Michelle A; Crockett, Amy; Covington-Kolb, Sarah; Simon, Melissa; Grobman, William A

    2017-04-01

    To compare gestational weight gain among women in group prenatal care with that of women in individual prenatal care. In this retrospective cohort study, women who participated in group prenatal care from 2009 to 2015 and whose body mass indexes (BMIs) and gestational weight gain were recorded were matched with the next two women who had the same payer type, were within 2-kg/m prepregnancy BMI and 2-week gestational age at delivery, and had received individual prenatal care. Bivariate comparisons of demographics and antenatal complications were performed for women in group and individual prenatal care, and weight gain was categorized as "below," "met," or "exceeded" goals according to the 2009 Institute of Medicine guidelines. Logistic regression analysis estimated the association between excessive weight gain and model of care, with adjustment for confounders, stratified by BMI. Women in group prenatal care (n=2,117) were younger and more commonly non-Hispanic black, nulliparous, and without gestational diabetes (P≤.005 for all). Women in group prenatal care more commonly exceeded the weight gain goals (55% compared with 48%, Pprenatal care, compared with individual prenatal care, is associated with excessive gestational weight gain.

  10. 26 CFR 1.669(f)-1A - Character of capital gain.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Character of capital gain. 1.669(f)-1A Section 1... Before January 1, 1969 § 1.669(f)-1A Character of capital gain. Amounts distributed as a capital gain... the gain had with respect to the trust. Thus, a capital gain that was taxed to the trust as a “long...

  11. Gain reduction measurements in transient stimulated Raman scattering

    NARCIS (Netherlands)

    Heeman, R.J.; Godfried, H.P

    1995-01-01

    Threshold energy measurements of transient rotational stimulated Raman scattering are compared to Raman conversion calculations from semiclassical theories using a simple concept of a gain reduction factor which expresses the reduction of the gain from its steady-state value due to transient

  12. Automated rapid chemistry in heavy element research

    International Nuclear Information System (INIS)

    Schaedel, M.

    1994-01-01

    With the increasingly short half-lives of the heavy element isotopes in the transition region from the heaviest actinides to the transactinide elements the demand for automated rapid chemistry techniques is also increasing. Separation times of significantly less than one minute, high chemical yields, high repetition rates, and an adequate detection system are prerequisites for many successful experiments in this field. The development of techniques for separations in the gas phase and in the aqueous phase for applications of chemical or nuclear studies of the heaviest elements are briefly outlined. Typical examples of results obtained with automated techniques are presented for studies up to element 105, especially those obtained with the Automated Rapid Chemistry Apparatus, ARCA. The prospects to investigate the properties of even heavier elements with chemical techniques are discussed

  13. Technology developments and first measurements of Low Gain Avalanche Detectors (LGAD) for high energy physics applications

    International Nuclear Information System (INIS)

    Pellegrini, G.; Fernández-Martínez, P.; Baselga, M.; Fleta, C.; Flores, D.; Greco, V; Hidalgo, S.; Mandić, I.; Kramberger, G.; Quirion, D.; Ullan, M.

    2014-01-01

    This paper introduces a new concept of silicon radiation detector with intrinsic multiplication of the charge, called Low Gain Avalanche Detector (LGAD). These new devices are based on the standard Avalanche Photo Diodes (APD) normally used for optical and X-ray detection applications. The main differences to standard APD detectors are the low gain requested to detect high energy charged particles, and the possibility to have fine segmentation pitches: this allows fabrication of microstrip or pixel devices which do not suffer from the limitations normally found [1] in avalanche detectors. In addition, a moderate multiplication value will allow the fabrication of thinner devices with the same output signal of standard thick substrates. The investigation of these detectors provides important indications on the ability of such modified electrode geometry to control and optimize the charge multiplication effect, in order to fully recover the collection efficiency of heavily irradiated silicon detectors, at reasonable bias voltage, compatible with the voltage feed limitation of the CERN High Luminosity Large Hadron Collider (HL-LHC) experiments [2]. For instance, the inner most pixel detector layers of the ATLAS tracker will be exposed to fluences up to 2×10 16 1 MeV n eq /cm 2 , while for the inner strip detector region fluences of 1×10 15 n eq /cm 2 are expected. The gain implemented in the non-irradiated devices must retain some effect also after irradiation, with a higher multiplication factor with respect to standard structures, in order to be used in harsh environments such those expected at collider experiments

  14. Gain-assisted control of the Goos-Haenchen shift

    Energy Technology Data Exchange (ETDEWEB)

    Ziauddin,; Qamar, Sajid [Centre for Quantum Physics, COMSATS Institute of Information Technology, Islamabad (Pakistan); Department of Physics, COMSATS Institute of Information Technology, Islamabad (Pakistan)

    2011-11-15

    A gain-assisted model is considered to study the Goos-Haenchen (GH) shift behavior in the reflected and transmitted light. In this model, a probe light is incident on a cavity containing three-level dilute gaseous atomic medium. The atom-field interaction follows two-photon Raman transitions, and the dielectric susceptibility of the medium exhibits dispersion and gain properties [L. J. Wang, A. Kuzmich, and A. Dogariu, Nature (London) 406, 227 (2000)]. Under appropriate conditions, two gain peaks are observed with anomalous dispersion between the peaks, whereas normal dispersion can be observed at and around the gain maxima. The manipulation of the detuning associated with the probe light field which interacts with the intracavity medium during its propagation through the cavity can lead to a control over negative and positive GH shift in the reflected and transmitted light beam via the anomalous and normal dispersion of the medium.

  15. Light propagation in composite materials with gain layers

    International Nuclear Information System (INIS)

    Dorofeenko, Aleksandr V; Zyablovsky, A A; Pukhov, Aleksandr A; Lisyansky, A A; Vinogradov, Aleksei P

    2012-01-01

    Light propagation through a single gain layer and a multilayer system with gain layers is studied. Results obtained using the Fresnel formulas, Airy's series summation, and the numerical solution of the nonlinear Maxwell-Bloch equations by the finite difference time domain (FDTD) method are analyzed and compared. Normal and oblique propagation of a wave through a gain layer and a slab of a photonic crystal are examined. For the latter problem, the gain line may be situated in either the pass or stop band of the photonic crystal. It is shown that the monochromatic plane-wave approximation is generally inapplicable for active media, because it leads to results that violate causality. But the problem becomes physically meaningful and correct results can be obtained for all three approaches once the structure of the wavefront and the finite aperture of the beam are taken into account. (reviews of topical problems)

  16. Thermogravimetric experiments with titanium

    International Nuclear Information System (INIS)

    Porter, L.J.; Longhurst, G.R.

    1991-02-01

    In the process of preparing for pyrophoricity experiments involving uranium, we conducted hydriding and air-exposure experiments on titanium. In these experiments the hydriding reactions and response to air-exposure was generally within the range expected based on work reported by others. One aberrant behavior was a sudden weight gain followed by a significant weight loss. We speculate that loss may be due to hydrogen evolution from the TiH 2 resulting from local heating by oxidation reactions. We verified that titanium is not pyrophoric at temperatures less than 750 degree C. 18 refs. 1 fig

  17. Antimicrobial susceptibility testing of rapidly growing mycobacteria by microdilution - Experience of a tertiary care centre

    Directory of Open Access Journals (Sweden)

    Set R

    2010-01-01

    Full Text Available Purpose: The objective of the study was to perform antimicrobial susceptibility testing of rapidly growing mycobacteria (RGM isolated from various clinically suspected cases of extrapulmonary tuberculosis, from January 2007 to April 2008, at a tertiary care centre in Mumbai. Materials and Methods: The specimens were processed for microscopy and culture using the standard procedures. Minimum inhibitory concentrations (MIC were determined by broth microdilution, using Sensititre CA MHBT. Susceptibility testing was also carried out on Mueller Hinton agar by the Kirby Bauer disc diffusion method. Results: Of the 1062 specimens received for mycobacterial cultures, 104 (9.79% grew mycobacteria. Of the mycobacterial isolates, six (5.76% were rapid growers. M. abscessus and M. chelonae appeared to be resistant organisms, with M. chelonae showing intermediate resistance to amikacin and minocycline. However, all the six isolates showed sensitivity to vancomycin and gentamicin by the disc diffusion test. Also all three isolates of M. abscessus were sensitive to piperacillin and erythromycin. Further studies are required to test their sensitivity to these four antimicrobials by using the microbroth dilution test, before they can be prescribed to patients. Conclusions: We wish to emphasize that reporting of rapidly growing mycobacteria from clinical settings, along with their sensitivity patterns, is an absolute need of the hour.

  18. Frijolito Watershed: Integrated investigations of a rapidly eroding pinyon-juniper hillslope

    International Nuclear Information System (INIS)

    Wilcox, B.P.; Pitlick, J.

    1995-01-01

    The dramatic acceleration of erosion associated with the expansion of pinyon-juniper woodlands over the past 100 years has been widely recognized, but few process-based studies of this phenomenon have been undertaken. In an attempt to identify the underlying causes, and the factors that affect erosion processes, we have initiated an interdisciplinary study of a rapidly eroding pinyon-juniper woodland in northern New Mexico. Since July 1993, we have collected data on runoff, erosion, and weather conditions from a 1-ha catchment study area and have conducted surveys of topography, soils, and vegetation. Our preliminary results indicate that although runoff makes up less than 10% of the annual water budget, runoff events - which are frequent in the summer - are capable of moving large amounts of sediment. We estimate that between July 1993 and October 1994, between 25,000 and 50,000 kg of sediment has eroded and been transported from the catchment. The information gained from such studies is essential to our ability to formulate effective strategies for managing these rapidly eroding woodlands

  19. Gain control network conditions in early sensory coding.

    Directory of Open Access Journals (Sweden)

    Eduardo Serrano

    Full Text Available Gain control is essential for the proper function of any sensory system. However, the precise mechanisms for achieving effective gain control in the brain are unknown. Based on our understanding of the existence and strength of connections in the insect olfactory system, we analyze the conditions that lead to controlled gain in a randomly connected network of excitatory and inhibitory neurons. We consider two scenarios for the variation of input into the system. In the first case, the intensity of the sensory input controls the input currents to a fixed proportion of neurons of the excitatory and inhibitory populations. In the second case, increasing intensity of the sensory stimulus will both, recruit an increasing number of neurons that receive input and change the input current that they receive. Using a mean field approximation for the network activity we derive relationships between the parameters of the network that ensure that the overall level of activity of the excitatory population remains unchanged for increasing intensity of the external stimulation. We find that, first, the main parameters that regulate network gain are the probabilities of connections from the inhibitory population to the excitatory population and of the connections within the inhibitory population. Second, we show that strict gain control is not achievable in a random network in the second case, when the input recruits an increasing number of neurons. Finally, we confirm that the gain control conditions derived from the mean field approximation are valid in simulations of firing rate models and Hodgkin-Huxley conductance based models.

  20. Learn and gain

    CERN Document Server

    Al-Alami, Suhair Eyad Jamal

    2013-01-01

    Initiating the slogan ""love it, live it"", Learn and Gain includes eight short stories, chosen to illustrate various modes of narration, as well as to provoke reflection and discussion on a range of issues. All texts utilized here illustrate how great writers can, with their insight and gift for words, help us to see the world we live in, in new probing and exciting ways. What characterises the book, the author believes, is the integration of the skills of literary competence, communicative c...