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Sample records for rapid-cycling synchrotrons rcs

  1. Observations of electrons in the Intense Pulse Neutron Source (IPNS) Rapid Cycling Synchrotron (RCS)

    International Nuclear Information System (INIS)

    Dooling, J.C.; Brumwell, F.R.; Czyz, W.S.; Harkay, K.C.; Lien, M.K.; McMichael, G.E.

    2004-01-01

    In the process of accelerating protons from 50 to 450 MeV at 30 Hz, low-energy electrons are generated within the IPNS RCS vacuum chamber. Electrons from background gas stripping are detected using an Ionization Profile Monitor (IPM) to generate integrated, horizontal charge distributions of the single-harmonic bunch during acceleration. Recently, a Retarding Field Analyzer (RFA) was installed in the RCS to look for evidence of beam-induced multipacting by measuring the electrons ejected by the space charge of the beam. A wide-band, high-gain transimpedance amplifier has been built to observe time structure in the electron signal detected with the RFA. Though a noisy power supply prevented full I-V characteristics from being obtained, interesting features are observed; especially, after the period of phase modulation between the rf cavities that is deliberately introduced during the cycle. The phase modulation generates a longitudinal quadrupole oscillation in the bunch, which is believed to enhance beam stability. Preliminary results indicate that electron multipacting is not significant in the RCS. The effects of background gas neutralization are considered and details of the RFA measurements are presented.

  2. Rapid cycling superconducting booster synchrotron

    International Nuclear Information System (INIS)

    Dinev, D.; Agapov, N.; Butenko, A.

    2001-01-01

    The existing set of Nuclotron heavy ion sources, such as duoplasmatron, polarized deuteron, laser and electron beam ion sources permits to have ion beams over a wide range of masses. The main problem for us now is to gain high intensity of accelerator particles. It can be solved by means of multiturn injection of the low current beams into the booster, acceleration up to the intermediate energies, stripping and transferring into the main ring. A design study of this accelerator - the 250 MeV/Amu Nuclotron booster synchrotron at 1 Hz repetition rate and circumference of 84 m, has been completed. The lattice dipole and quadrupole magnets have an iron yoke coils, made of hollow superconductor, are cooled by two-phase Helium flow, as well as the Nuclotron magnets. (authors)

  3. Tune-control improvements on the rapid-cycling synchrotron

    International Nuclear Information System (INIS)

    Potts, C.; Faber, M.; Gunderson, G.; Knott, M.; Voss, D.

    1981-01-01

    The as-built lattice of the Rapid-Cycling Synchrotron (RCS) had two sets of correction sextupoles and two sets of quadrupoles energized by dc power supplies to control the tune and the tune tilt. With this method of powering these magnets, adjustment of tune conditions during the accelerating cycle as needed was not possible. A set of dynamically programmable power supplies has been built and operated to provide the required chromaticity adjustment. The short accelerating time (16.7 ms) of the RCS and the inductance of the magnets dictated large transistor amplifier power supplies. The required time resolution and waveform flexibility indicated the desirability of computer control. Both the amplifiers and controls are described, along with resulting improvements in the beam performance. A set of octupole magnets and programmable power supplies with similar dynamic qualities have been constructed and installed to control the anticipated high-intensity transverse instability. This system will be operational in the spring of 1981

  4. Space-Charge Simulation of Integrable Rapid Cycling Synchrotron

    Energy Technology Data Exchange (ETDEWEB)

    Eldred, Jeffery [Fermilab; Valishev, Alexander [Fermilab

    2017-05-01

    Integrable optics is an innovation in particle accelerator design that enables strong nonlinear focusing without generating parametric resonances. We use a Synergia space-charge simulation to investigate the application of integrable optics to a high-intensity hadron ring that could replace the Fermilab Booster. We find that incorporating integrability into the design suppresses the beam halo generated by a mismatched KV beam. Our integrable rapid cycling synchrotron (iRCS) design includes other features of modern ring design such as low momentum compaction factor and harmonically canceling sextupoles. Experimental tests of high-intensity beams in integrable lattices will take place over the next several years at the Fermilab Integrable Optics Test Accelerator (IOTA) and the University of Maryland Electron Ring (UMER).

  5. Multi-function ring magnet power supply for rapid-cycling synchrotrons

    International Nuclear Information System (INIS)

    Praeg, W.F.

    1985-01-01

    Ring magnet power supply (RMPS) circuits that produce a wide range of magnet current waveshapes for rapid-cycling synchrotrons (RCS) are described. The shapes range from long flat-tops separated by a biased dual frequency cosine wave to those having a flat-bottom (injection), followed by a lower frequency cosine half wave (acceleration), a flat-top (extraction), and a higher frequency cosine half wave (magnet reset). Applications of these circuits for proposed synchrotrons are outlined. Solid-state switching circuits and the results of proof-of-concept tests are shown. 8 refs., 12 figs

  6. The Rapid Cycling Synchrotron of the EURISOL Beta-Beam facility

    CERN Document Server

    Lachaize, A

    During the last two years, several upgrades of the initial baseline scenario were studied with the aim of increasing the average intensity of ion beams in the accelerator chain of the Beta Beam complex. This is the reason why the Rapid Cycling Synchrotron (RCS) specifications were reconsidered many times.General considerations on the optical design were presented at the Beta Beam Task Meetings held at CERN and at Saclay in 2005 (http://beta-beam.web.cern.ch/beta-beam/). More detailed beam optics studies were performed during the next months. Lattices, RF system parameters, multi-turn injection scheme, fast extraction, closed orbit correction and chromaticity correction systems were proposed for different versions of the RCS.Finally, the RCS specifications have stabilized in November 2006 after the fourth Beta Beam Task Meeting when it was decided to fix the maximum magnetic rigidity of ion beams to 14.47 T.m (3.5 GeV equivalent proton energy) and to adopt a ring physical radius of 40 m in order to facilitat...

  7. Dual-harmonic auto voltage control for the rapid cycling synchrotron of the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    Fumihiko Tamura

    2008-07-01

    Full Text Available The dual-harmonic operation, in which the accelerating cavities are driven by the superposition of the fundamental and the second harmonic rf voltage, is useful for acceleration of the ultrahigh intensity proton beam in the rapid cycling synchrotron (RCS of Japan Proton Accelerator Research Complex (J-PARC. However, the precise and fast voltage control of the harmonics is necessary to realize the dual-harmonic acceleration. We developed the dual-harmonic auto voltage control system for the J-PARC RCS. We describe details of the design and the implementation. Various tests of the system are performed with the RCS rf system. Also, a preliminary beam test has been done. We report the test results.

  8. Beam commissioning of the 3-GeV rapid cycling synchrotron of the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    H. Hotchi

    2009-04-01

    Full Text Available The 3-GeV rapid cycling synchrotron (RCS of the Japan Proton Accelerator Research Complex (J-PARC was commissioned in October 2007, and successfully accomplished 3 GeV acceleration on October 31. Six run cycles through February 2008 were dedicated to commissioning the RCS, for which the initial machine parameter tuning and various underlying beam studies were completed. Then since May 2008 the RCS beam has been delivered to the downstream facilities for their beam commissioning. In this paper we describe beam tuning and study results following our beam commissioning scenario and a beam performance and operational experience obtained in the first commissioning phase through June 2008.

  9. Proposed second harmonic acceleration system for the intense pulsed neutron source rapid cycling synchrotron

    International Nuclear Information System (INIS)

    Norem, J.; Brandeberry, F.; Rauchas, A.

    1983-01-01

    The Rapid Cycling Synchrotron (RCS) of the Intense Pulsed Neutron Source (IPNS) operating at Argonne National Laboratory is presently producing intensities of 2 to 2.5 x 10 12 protons per pulse (ppp) with the addition of a new ion source. This intensity is close to the space charge limit of the machine, estimated at approx.3 x 10 12 ppp, depending somewhat on the available aperture. With the present good performance in mind, accelerator improvements are being directed at: (1) increasing beam intensities for neutron science; (2) lowering acceleration losses to minimize activation; and (3) gaining better control of the beam so that losses can be made to occur when and where they can be most easily controlled. On the basis of preliminary measurements, we are now proposing a third cavity for the RF systems which would provide control of the longitudinal bunch shape during the cycle which would permit raising the effective space charge limit of the accelerator and reducing losses

  10. Phase lock of rapid cycling synchrotron and neutron choppers

    International Nuclear Information System (INIS)

    Praeg, W.; McGhee, D.; Volk, G.

    1981-01-01

    The 500-MeV synchrotron of Argonne's Intense Pulsed Neutron Source operates at 30 Hz. Its beam spill must be locked to neutron choppers with a precision of +- 0.5 μs. A chopper and an accelerator have large and different inertias. This makes synchronization by phase lock to the 60-Hz power line extremely difficult. We solved the phasing problems by running both the Ring Magnet Power Supply (RMPS) of the synchrotron and the chopper motors from a common oscillator that is stable to 1 ppM and by controlling five quantities of the RMPS. The quantities controlled by feedback loops are dc current, injection current, ejection current, resonant frequency, and the phase shift between the synchrotron peak field and the chopper window

  11. Thermal analysis of injection beam dump of high-intensity rapid-cycling synchrotron in J-PARC

    Science.gov (United States)

    Kamiya, J.; Saha, P. K.; Yamamoto, K.; Kinsho, M.; Nihei, T.

    2017-10-01

    The beam dump at the beam injection area in the J-PARC 3-GeV rapid cycling synchrotron (RCS) accepts beams that pass through the charge exchange foil without ideal electron stripping during the multi-turn beam injection. The injection beam dump consists of the beam pipe, beam stopper, radiation shield, and cooling mechanism. The ideal beam power into the injection beam dump is 400 W in the case of design RCS extraction beam power of 1 MW with a healthy foil, which has 99.7 % charge stripping efficiency. On the other hand, as a radiation generator, the RCS is permitted to be operated with maximum average beam power of 4 kW into the injection beam dump based on the radiation shielding calculation, in consideration of lower charge stripping efficiency due to the foil deterioration. In this research, to evaluate the health of the RCS injection beam dump system from the perspective of the heat generation, a thermal analysis was performed based on the actual configuration with sufficiently large region, including the surrounding concrete and soil. The calculated temperature and heat flux density distribution showed the validity of the mesh spacing and model range. The calculation result showed that the dumped 4 kW beam causes the temperature to increase up to 330, 400, and 140 °C at the beam pipe, beam stopper, and radiation shield, respectively. Although these high temperatures induce stress in the constituent materials, the calculated stress values were lower than the ultimate tensile strength of each material. Transient temperature analysis of the beam stopper, which simulated the sudden break of the charge stripper foil, demonstrated that one bunched beam pulse with the maximum beam power does not lead to a serious rise in the temperature of the beam stopper. Furthermore, from the measured outgassing rate of stainless steel at high temperature, the rise in beam line pressure due to additive outgassing from the heated beam pipe was estimated to have a negligible

  12. Beam loss reduction by injection painting in the 3-GeV rapid cycling synchrotron of the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    H. Hotchi

    2012-04-01

    Full Text Available The 3-GeV rapid cycling synchrotron (RCS of the Japan Proton Accelerator Research Complex was commissioned in October 2007. Via the initial beam tuning and a series of underlying beam studies with low-intensity beams, since December 2009, we have intermittently been performing beam tuning experiments with higher-intensity beams including the injection painting technique. By optimizing the injection painting parameters, we have successfully achieved a 420 kW-equivalent output intensity at a low-level intensity loss of less than 1%. Also the corresponding numerical simulation well reproduced the observed painting parameter dependence on the beam loss, and captured a characteristic behavior of the high-intensity beam in the injection painting process. In this paper, we present the experimental results obtained in the course of the RCS beam power ramp-up, especially on the beam loss reduction achieved by employing the injection painting, together with the numerical simulation results.

  13. Direct observation of the phase space footprint of a painting injection in the Rapid Cycling Synchrotron at the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    P. K. Saha

    2009-04-01

    Full Text Available The 3 GeV Rapid Cycling Synchrotron (RCS at Japan Proton Accelerator Research Complex is nearly at the operational stage with regard to the beam commissioning aspects. Recently, the design painting injection study has been commenced with the aim of high output beam power at the extraction. In order to observe the phase space footprint of the painting injection, a method was developed utilizing a beam position monitor (BPM in the so-called single pass mode. The turn-by-turn phase space coordinates of the circulating beam directly measured using a pair of BPMs entirely positioned in drift space, and the calculated transfer matrices from the injection point to the pair of BPMs with several successive turns were used together in order to obtain the phase space footprint of the painting injection. There are two such pairs of BPMs placed in two different locations in the RCS, the results from which both agreed and were quite consistent with what was expected.

  14. Direct observation of the phase space footprint of a painting injection in the Rapid Cycling Synchrotron at the Japan Proton Accelerator Research Complex

    Science.gov (United States)

    Saha, P. K.; Shobuda, Y.; Hotchi, H.; Hayashi, N.; Takayanagi, T.; Harada, H.; Irie, Y.

    2009-04-01

    The 3 GeV Rapid Cycling Synchrotron (RCS) at Japan Proton Accelerator Research Complex is nearly at the operational stage with regard to the beam commissioning aspects. Recently, the design painting injection study has been commenced with the aim of high output beam power at the extraction. In order to observe the phase space footprint of the painting injection, a method was developed utilizing a beam position monitor (BPM) in the so-called single pass mode. The turn-by-turn phase space coordinates of the circulating beam directly measured using a pair of BPMs entirely positioned in drift space, and the calculated transfer matrices from the injection point to the pair of BPMs with several successive turns were used together in order to obtain the phase space footprint of the painting injection. There are two such pairs of BPMs placed in two different locations in the RCS, the results from which both agreed and were quite consistent with what was expected.

  15. Design, Manufacture and Test of a 1.3 T / 10 Hz dipole model for Rapid Cycling Synchrotrons

    CERN Document Server

    Newborough, A

    2013-01-01

    The construction of a compact rapid cycling synchrotron has recently been studied at CERN to replace the first stage of its accelerator complex, the proton synchrotron booster. Although currently there are no plans to build this machine, fast cycled accelerator magnets are of general interest for numerous reasons. This has led to the design, manufacture and testing of a scaled model dipole as detailed in this paper to show the capability of producing and characterising a magnet design based on high-silicon content grain-oriented steel able to operate up to 1.3 T at 10 Hz.

  16. Simulation, measurement, and mitigation of beam instability caused by the kicker impedance in the 3-GeV rapid cycling synchrotron at the Japan Proton Accelerator Research Complex

    Science.gov (United States)

    Saha, P. K.; Shobuda, Y.; Hotchi, H.; Harada, H.; Hayashi, N.; Kinsho, M.; Tamura, F.; Tani, N.; Yamamoto, M.; Watanabe, Y.; Chin, Yong Ho; Holmes, J. A.

    2018-02-01

    The transverse impedance of eight extraction pulsed kicker magnets is a strong beam instability source in the 3-GeV rapid cycling synchrotron (RCS) at the Japan Proton Accelerator Research Complex. Significant beam instability occurs even at half of the designed 1 MW beam power when the chromaticity (ξ ) is fully corrected for the entire acceleration cycle by using ac sextupole (SX) fields. However, if ξ is fully corrected only at the injection energy by using dc SX fields, the beam is stable. In order to study realistic beam instability scenarios, including the effect of space charge and to determine practical measures to accomplish 1 MW beam power, we enhance the orbit particle tracking code to incorporate all realistic time-dependent machine parameters, including the time dependence of the impedance itself. The beam stability properties beyond 0.5 MW beam power are found to be very sensitive to a number of parameters in both simulations and measurements. In order to stabilize a beam at 1 MW beam power, two practical measures based on detailed and systematic simulation studies are determined, namely, (i) proper manipulation of the betatron tunes during acceleration and (ii) reduction of the dc SX field to reduce the ξ correction even at injection. The simulation results are well reproduced by measurements, and, as a consequence, an acceleration to 1 MW beam power is successfully demonstrated. In this paper, details of the orbit simulation and the corresponding experimental results up to 1 MW of beam power are presented. To further increase the RCS beam power, beam stability issues and possible measures beyond 1 MW beam power are also considered.

  17. Design study of the large hadron electron collider and a rapid cycling synchrotron as alternative to the PS booster upgrade at CERN

    International Nuclear Information System (INIS)

    Fitterer, Miriam

    2013-01-01

    With the Large Hadron Collider (LHC) the exploration of particle physics at center of mass energies at the TeV scale has begun. To extend the discovery potential of the LHC, a major upgrade is foreseen around 2020 of the LHC itself and the LHC injectors - the chain of accelerators preparing the beam for the LHC. One of the injectors - the second one in the chain - is the Proton Synchrotron (PS) Booster. Its performance is currently limited by the space-charge effect, which is the effect of the electromagnetic field of the particle beam on itself. This effect becomes weaker with higher energy, and therefore an energy upgrade of the PS Booster to 2 GeV maximum beam energy is foreseen. As the PS Booster is with its 40 years already an old machine, the construction of a new accelerator, a Rapid Cycling Synchrotron (RCS), to replace the PS Booster has been proposed. In this thesis different options for the beam guidance in the RCS - referred to as lattice and optics - are studied, followed by a more general comparison of different lattices and optics and their performance under consideration of the space-charge effect. To further complement the LHC physics program, also the possibility of deep inelastic lepton-nucleon scattering at the LHC has been suggested, referred to as Large Hadron Electron Collider (LHeC). In this case the proton beam of the LHC collides with the electron beam, which is accelerated in a separate newly built machine. Two options are considered as electron accelerator: a new energy recovery linac - the Linac-Ring option - and the installation of an electron ring in the existing LHC tunnel - the Ring-Ring option. One of the main challenges of the Ring-Ring option is the integration of the electron ring in the current LHC tunnel. A layout, lattice and optics of the electron accelerator is developed in this thesis, which meets the requirements with regard to integration and reaches the beam parameters demanded by the particle physics experiments.

  18. Design study of the large hadron electron collider and a rapid cycling synchrotron as alternative to the PS booster upgrade at CERN

    Energy Technology Data Exchange (ETDEWEB)

    Fitterer, Miriam

    2013-02-22

    With the Large Hadron Collider (LHC) the exploration of particle physics at center of mass energies at the TeV scale has begun. To extend the discovery potential of the LHC, a major upgrade is foreseen around 2020 of the LHC itself and the LHC injectors - the chain of accelerators preparing the beam for the LHC. One of the injectors - the second one in the chain - is the Proton Synchrotron (PS) Booster. Its performance is currently limited by the space-charge effect, which is the effect of the electromagnetic field of the particle beam on itself. This effect becomes weaker with higher energy, and therefore an energy upgrade of the PS Booster to 2 GeV maximum beam energy is foreseen. As the PS Booster is with its 40 years already an old machine, the construction of a new accelerator, a Rapid Cycling Synchrotron (RCS), to replace the PS Booster has been proposed. In this thesis different options for the beam guidance in the RCS - referred to as lattice and optics - are studied, followed by a more general comparison of different lattices and optics and their performance under consideration of the space-charge effect. To further complement the LHC physics program, also the possibility of deep inelastic lepton-nucleon scattering at the LHC has been suggested, referred to as Large Hadron Electron Collider (LHeC). In this case the proton beam of the LHC collides with the electron beam, which is accelerated in a separate newly built machine. Two options are considered as electron accelerator: a new energy recovery linac - the Linac-Ring option - and the installation of an electron ring in the existing LHC tunnel - the Ring-Ring option. One of the main challenges of the Ring-Ring option is the integration of the electron ring in the current LHC tunnel. A layout, lattice and optics of the electron accelerator is developed in this thesis, which meets the requirements with regard to integration and reaches the beam parameters demanded by the particle physics experiments.

  19. The rapid cycling synchrotron of the Eurisol / Beta-Beam facility

    International Nuclear Information System (INIS)

    Lachaize, A.

    2008-09-01

    In order to ask for physicians requests, some neutrinos facilities are under studies to produce pure, intense, well collimated neutrinos beams with a well determined energy spectrum. One of them, the Beta-Beam project, is based on neutrinos production by radioactive ion beams decay after acceleration. The thesis is focused on one step of the complex, namely the low energy ring required for accumulation and injection of ion beams between the post-acceleration linac of the EURISOL complex (dedicated complex for radioactive ion beam production) and the CERN PS. After the description of the EURISOL complex and the Beta-Beam complex, a description of charged particles beams transport formalism is given. Then, in the second part, studies on the definition and the optimisation of the ring are given, starting by optical structure then different simulations concerning beam dynamics, i.e. multiturn injection, synchronous acceleration with beam losses localization and intensity, fast extraction, chromaticity with eddy currents correction and space charge effects. Finally, a preliminary technical design of the RCS main magnets is proposed. (author)

  20. Control System of 3 GeV Rapid Cycling Synchrotron at J-PARC

    CERN Document Server

    Takahashi, Hiroki; Kato, Yuko; Kawase, Masato; Sakaki, Hironao; Sako, Hiroyuki; Sugimoto, Makoto; Yoshikawa, Hiroshi

    2005-01-01

    Since the 3GeV RCS produces huge beam power of 1 MW, extreme cares must be taken to design the control system in order to minimize radiation due to beam loss. Another complexity appears in the control system, because each beam bunch of 25 Hz is required to be injected either into the MLF* or into the 50GeV MR.** Therefore, each bunch of 25 Hz must be operated separately, and the data acquisition system must collect synchronized data within each pulse. To achieve these goals, a control system via reflective memory and wave endless recorders has been developed. EPICS is adopted in the control system. Since the number of devices is huge, the management of EPICS records and their configurations require huge amount of time and man power. To reduce this work significantly, a RDB*** for static machine information has been developed. This RDB stores (1) EPICS related information of devices, interfaces, and IOC's**** with a capability to generate EPICS records automatically, and (2) machine geometrical information wit...

  1. Conceptual design of a rapid-cycling synchrotron for the KFA-Juelich spallation neutron source: working papers

    International Nuclear Information System (INIS)

    1983-01-01

    An accelerator group was established at ANL by the request of KFA-Juelich to carry out a conceptual design study and cost estimate for a rapid-cycling synchrotron as a possible first stage program on spallation neutron sources at KFA-Juelich. This set of notes is the individual notes which form the basis of the final report under this proposal prepared in January 1983. The topics covered include: SNQ Synchrotron Lattice-I; injection and extraction orbit; extraction from SNQ-SRA; SRA injection; capture and acceleration considerations in the SNQ-SRA; longitudinal coupling impedance; power supplies for SNQ synchrotron proposals; space charge limits in the SNQ-SRA; error analysis; SNQ-SRA ring magnets preliminary designs and cost; summary of CERN booster 4-ring arrangement; V-lattices for SNQ-SRA and extraction from the V-lattices; rf parameters for capture, acceleration and extraction; some parameters of the SNQ-SRA injector system; Keil-Schnell criterion; risetime of longitudinal resistive wall instability; beam scrapers; a design of the vacuum system; some aspects of vacuum consideration for SNQ-SRA; choice working points; ring magnet power supplies for shaped extaction of 1.1 GeV SNQ; ring magnet design and costs; tune shift due to the fringing field of the quadrupoles; coherent instability due to ions in the residual gas; transverse stabilization of bunched beams; rf acceleration system; injection into the SRA; Landau damping to get transverse stability; chromaticity and amplitude dependent tune controls in the SNQ-SRA; conversion of the SNQ-SRA to a compressor ring; comments on beam loss; summary of longitudinal stability study and transverse stability study for the SNQ-SRA; and the beam stay clear regions of the SNQ-SRA

  2. Integrable RCS as a Proposed Replacement for Fermilab Booster

    Energy Technology Data Exchange (ETDEWEB)

    Eldred, Jeffrey [Fermilab; Valishev, Alexander [Fermilab

    2017-03-07

    Integrable optics is an innovation in particle accelerator design that potentially enables a greater betatron tune spread and damps collective instabilities. An integrable rapid-cycling synchrotron (RCS) would be an effective replacement for the Fermilab Booster, as part of a plan to reach multi-MW beam power at 120 GeV for the Fermilab high-energy neutrino program. We provide an example integrable lattice with features of a modern RCS - dispersion-free drifts, low momentum compaction factor, superperiodicity, chromaticity correction, bounded beta functions, and separate-function magnets.

  3. Beam loss caused by edge focusing of injection bump magnets and its mitigation in the 3-GeV rapid cycling synchrotron of the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    H. Hotchi

    2016-01-01

    Full Text Available In the 3-GeV rapid cycling synchrotron of the Japan Proton Accelerator Research Complex, transverse injection painting is utilized not only to suppress space-charge induced beam loss in the low energy region but also to mitigate foil scattering beam loss during charge-exchange injection. The space-charge induced beam loss is well minimized by the combination of modest transverse painting and full longitudinal painting. But, for sufficiently mitigating the foil scattering part of beam loss, the transverse painting area has to be further expanded. However, such a wide-ranging transverse painting had not been realized until recently due to beta function beating caused by edge focusing of pulsed injection bump magnets during injection. This beta function beating additionally excites random betatron resonances through a distortion of the lattice superperiodicity, and its resultant deterioration of the betatron motion stability causes significant extra beam loss when expanding the transverse painting area. To solve this issue, we newly installed pulse-type quadrupole correctors to compensate the beta function beating. This paper presents recent experimental results on this correction scheme for suppressing the extra beam loss, while discussing the beam loss and its mitigation mechanisms with the corresponding numerical simulations.

  4. Low Level RF Control System of J-PARC Synchrotrons

    CERN Document Server

    Tamura, Fumihiko; Ezura, Eizi; Hara, Keigo; Nomura, Masahiro; Ohmori, Chihiro; Schnase, Alexander; Takagi, Akira; Yamamoto, Masanobu; Yoshii, Masahito

    2005-01-01

    We present the concept and the design of the low level RF (LLRF) control system of the J-PARC synchrotrons. The J-PARC synchrotrons are the rapid cycling 3-GeV synchrotron (RCS) and the 50-GeV main ring (MR) which require very precise and stable LLRF control systems to accelerate the ultra-high proton beam current. The LLRF system of the synchrotron is a full-digital system based on the direct digital synthesis (DDS). The functions of the system are (1) the multi-harmonic RF generation for the acceleration and the longitudinal bunch shaping, (2) the feedbacks for stabilizing the beam, (3) the feedforward for compensating the heavy beam loading, and (4) other miscellaneous functions such as the synchronization and chopper timing. The LLRF system of the RCS is now under construction. We present the details of the system. Also, we show preliminary results of performance tests of the control modules.

  5. Design Considerations for Proposed Fermilab Integrable RCS

    Energy Technology Data Exchange (ETDEWEB)

    Eldred, Jeffrey [Fermilab; Valishev, Alexander

    2017-03-02

    Integrable optics is an innovation in particle accelerator design that provides strong nonlinear focusing while avoiding parametric resonances. One promising application of integrable optics is to overcome the traditional limits on accelerator intensity imposed by betatron tune-spread and collective instabilities. The efficacy of high-intensity integrable accelerators will be undergo comprehensive testing over the next several years at the Fermilab Integrable Optics Test Accelerator (IOTA) and the University of Maryland Electron Ring (UMER). We propose an integrable Rapid-Cycling Synchrotron (iRCS) as a replacement for the Fermilab Booster to achieve multi-MW beam power for the Fermilab high-energy neutrino program. We provide a overview of the machine parameters and discuss an approach to lattice optimization. Integrable optics requires arcs with integer-pi phase advance followed by drifts with matched beta functions. We provide an example integrable lattice with features of a modern RCS - long dispersion-free drifts, low momentum compaction, superperiodicity, chromaticity correction, separate-function magnets, and bounded beta functions.

  6. Synchrotron based spallation neutron source concepts

    International Nuclear Information System (INIS)

    Cho, Y.

    1998-01-01

    During the past 20 years, rapid-cycling synchrotrons (RCS) have been used very productively to generate short-pulse thermal neutron beams for neutron scattering research by materials science communities in Japan (KENS), the UK (ISIS) and the US (IPNS). The most powerful source in existence, ISIS in the UK, delivers a 160-kW proton beam to a neutron-generating target. Several recently proposed facilities require proton beams in the MW range to produce intense short-pulse neutron beams. In some proposals, a linear accelerator provides the beam power and an accumulator ring compresses the pulse length to the required ∼ 1 micros. In others, RCS technology provides the bulk of the beam power and compresses the pulse length. Some synchrotron-based proposals achieve the desired beam power by combining two or more synchrotrons of the same energy, and others propose a combination of lower and higher energy synchrotrons. This paper presents the rationale for using RCS technology, and a discussion of the advantages and disadvantages of synchrotron-based spallation sources

  7. VXIbus-based signal generator for resonant power supply system of the 3 GeV RCS

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Fengqing; Watanabe, Yasuhiro; Koseki, Shoichiro; Tani, Norio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Adachi, Toshikazu; Someya, Hirohiko [High Energy Accelerator Reseach Organization, Tsukuba, Ibaraki (Japan)

    2002-03-01

    The 3 GeV Proton RCS of the JAERI-KEK Joint Project is a 25 Hz separate-function rapid cycling synchrotron under design. Bending magnets (BM) and quadrupole magnets (QM) are excited separately. The 3 GeV RCS requests above 10 families of magnets excited independently, far beyond 3 families in practical RCS's. Difficulty of field tracking between BM and QM is significantly increased. Magnet strings are grouped into resonant networks and excited resonantly with power supplies driven by a waveform pattern, typically a DC-biased sinusoidal signal. To achieve a close tracking between many families, the driving signal of each power supply should be adjusted in phase and amplitude flexibly and dynamically. This report proposes a signal generator based on VXIbus. The VXIbus, an extension of VMEbus (VME eXtensions for Instrument), provides an open architecture with shared process bus and timing. The VXIbus-based signal generator facilitates the timing synchronization and is easy to extend to many channels needed by the 3 GeV RCS. Experimental results of the signal generator are reported. (author)

  8. Magnetic fringe field interference between the quadrupole and corrector magnets in the CSNS/RCS

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Mei, E-mail: yangmei@ihep.ac.cn [Key Laboratory of Particle Acceleration Physics and Technology, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China); China Spallation Neutron Source, Institute of High Energy Physics, Chinese Academy of Sciences, Dongguan 523803,China (China); Dongguan Neutron Science Center, Dongguan 523808,China (China); Kang, Wen; Deng, Changdong [Key Laboratory of Particle Acceleration Physics and Technology, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China); China Spallation Neutron Source, Institute of High Energy Physics, Chinese Academy of Sciences, Dongguan 523803,China (China); Dongguan Neutron Science Center, Dongguan 523808,China (China); Sun, Xianjing [Key Laboratory of Particle Acceleration Physics and Technology, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China); Li, Li; Wu, Xi [Key Laboratory of Particle Acceleration Physics and Technology, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China); China Spallation Neutron Source, Institute of High Energy Physics, Chinese Academy of Sciences, Dongguan 523803,China (China); Dongguan Neutron Science Center, Dongguan 523808,China (China); Gong, Lingling; Cheng, Da [Key Laboratory of Particle Acceleration Physics and Technology, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Zhu, Yingshun; Chen, Fusan [Key Laboratory of Particle Acceleration Physics and Technology, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China)

    2017-03-01

    The Rapid Cycling Synchrotron (RCS) of the China Spallation Neutron Source (CSNS) employs large aperture quadrupole and corrector magnets with small aspect ratios and relatively short iron to iron separations; so the fringe field interference becomes serious which results in integral field strength reduction and extra field harmonics. We have performed 3D magnetic field simulations to investigate the magnetic field interference in the magnet assemblies and made some adjustments on the magnet arrangement. The Fourier analysis is used to quantify the integral gradient reduction and field harmonic changes of the quadrupole magnets. Some magnetic field measurements are undertaken to verify the simulation results. The simulation details and the major results are presented in this paper.

  9. Simulation experiment on low-level RF control for dual-harmonic acceleration at CSNS RCS

    International Nuclear Information System (INIS)

    Shen Sirong; Li Xiao; Zhang Chunlin; Sun Hong; Tang Jingyu

    2013-01-01

    The design and test of the low-level RF (LLRF) control system for the dual-harmonic acceleration at the rapid cycling synchrotron (RCS) of China Spallation Neutron Source (CSNS) at phase Ⅰ is introduced. In order to implement the mode switch from the second harmonic to the fundamental during the acceleration cycle for one of the eight RF cavities, the LLRF system for the cavity has been designed differently from the others. Several technical measures such as the opening of the control loops during the mode switch and the reclosing of two tuning circuits of the RF amplifier at different moments, have been taken. The experimental results on the testing platform based on an RF prototype show good dynamic performance of the LLRF system and prove the feasibility of dual-harmonic operation. (authors)

  10. Rapid-Cycling Bubble-Chamber, details

    CERN Multimedia

    CERN PhotoLab

    1980-01-01

    Parts of the hydraulic expansion system of the Rapid-Cycling Bubble-Chamber (RCBC). RCBC was the largest of 3 rapid-cycling bubble-chambers (the others were LEBC and HOLEBC), used as target- and vertex-detectors within the European Hybrid Spectrometer (EHS) in the SPS North Area (EHN1). RCBC contained 250 l of liquid hydrogen and was located inside a 3 T superconducting magnet. It was designed for 30 expansions/s (100 times faster than BEBC), the system shown here allowed 50 expansions/s. RCBC operated from 1981 to 1983 for experiments NA21, NA22 and NA23 at a rate of 15 expansions/s, clocking up a total of over 4 million. In the rear, at left, is bearded Lucien Veillet; Augustin Didona is at the right. See also 8001009. The installation of the piston assembly in the RCBC chamber body is shown in the Annual Report 1980, p.65.

  11. Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients

    NARCIS (Netherlands)

    Kupka, RW; Luckenbaugh, DA; Post, RM; Suppes, T; Altshuler, LL; Keck, PE; Frye, MA; Denicoff, KD; Grunze, H; Leverich, GS; McElroy, SL; Walden, J; Nolen, WA

    Objective: To detect risk factors for rapid cycling in bipolar disorder, the authors compared characteristics of rapid-cycling and non-rapid-cycling patients both from a categorical and a dimensional perspective. Method: Outpatients with bipolar I disorder (N = 419), bipolar II disorder (N = 104),

  12. Cognitive-Behavioral Therapy for Rapid Cycling Bipolar Disorder

    Science.gov (United States)

    Reilly-Harrington, Noreen A.; Knauz, Robert O.

    2005-01-01

    This article describes the application of cognitive-behavioral therapy (CBT) to the treatment of rapid cycling bipolar disorder. Between 10% and 24% of bipolar patients experience a rapid cycling course, with 4 or more mood episodes occurring per year. Characterized by nonresponse to standard mood-stabilizing medications, rapid cyclers are…

  13. Polarized e-bunch acceleration at Cornell RCS: Tentative tracking simulations

    Energy Technology Data Exchange (ETDEWEB)

    Meot, F. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ptitsyn, V. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ranjbar, V. [Brookhaven National Lab. (BNL), Upton, NY (United States); Rubin, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-10-19

    An option as an injector into eRHIC electron storage ring is a rapid-cyclic synchrotron (RCS). Rapid acceleration of polarized electron bunches has never been done, Cornell synchrotron might lend itself to dedicated tests, which is to be first explored based on numerical investigations. This paper is a very preliminary introduction to the topic.

  14. Next Generation Life Support (NGLS): Rapid Cycle Amine Swing Bed

    Data.gov (United States)

    National Aeronautics and Space Administration — The Rapid Cycle Amine (RCA) swingbed has been identified as a technology with high potential to meet the stringent requirements for the next generation spacesuit's...

  15. Rapid-cycle testing cuts bed turnaround by 85%.

    Science.gov (United States)

    2004-11-01

    You can use rapid-cycle testing to try out new approaches to overcrowding much more frequently than with more traditional process improvement strategies. Improving bed turnaround notification can yield dramatic improvements. Telling staff they have to try a new process only for three days makes it easier to gain buy-in. Look for old policies that are no longer needed, yet continue to keep your staff bogged down.

  16. Orbiter OMS and RCS technology

    Science.gov (United States)

    Boudreaux, R. A.

    1982-01-01

    Orbiter Orbital Maneuver Subsystem (OMS) and Reaction Control Subsystem (RCS) tankage has proved to be highly successful in shuttle flights on-orbit propellant transfer tests were done. Tank qualification tests along with flight demonstrations were carried out future uses of storable propellants are cited.

  17. Rapid Cycling Genomic Selection in a Multiparental Tropical Maize Population.

    Science.gov (United States)

    Zhang, Xuecai; Pérez-Rodríguez, Paulino; Burgueño, Juan; Olsen, Michael; Buckler, Edward; Atlin, Gary; Prasanna, Boddupalli M; Vargas, Mateo; San Vicente, Félix; Crossa, José

    2017-07-05

    Genomic selection (GS) increases genetic gain by reducing the length of the selection cycle, as has been exemplified in maize using rapid cycling recombination of biparental populations. However, no results of GS applied to maize multi-parental populations have been reported so far. This study is the first to show realized genetic gains of rapid cycling genomic selection (RCGS) for four recombination cycles in a multi-parental tropical maize population. Eighteen elite tropical maize lines were intercrossed twice, and self-pollinated once, to form the cycle 0 (C 0 ) training population. A total of 1000 ear-to-row C 0 families was genotyped with 955,690 genotyping-by-sequencing SNP markers; their testcrosses were phenotyped at four optimal locations in Mexico to form the training population. Individuals from families with the best plant types, maturity, and grain yield were selected and intermated to form RCGS cycle 1 (C 1 ). Predictions of the genotyped individuals forming cycle C 1 were made, and the best predicted grain yielders were selected as parents of C 2 ; this was repeated for more cycles (C 2 , C 3 , and C 4 ), thereby achieving two cycles per year. Multi-environment trials of individuals from populations C 0, C 1 , C 2 , C 3 , and C 4 , together with four benchmark checks were evaluated at two locations in Mexico. Results indicated that realized grain yield from C 1 to C 4 reached 0.225 ton ha -1 per cycle, which is equivalent to 0.100 ton ha -1  yr -1 over a 4.5-yr breeding period from the initial cross to the last cycle. Compared with the original 18 parents used to form cycle 0 (C 0 ), genetic diversity narrowed only slightly during the last GS cycles (C 3 and C 4 ). Results indicate that, in tropical maize multi-parental breeding populations, RCGS can be an effective breeding strategy for simultaneously conserving genetic diversity and achieving high genetic gains in a short period of time. Copyright © 2017 Zhang et al.

  18. Biological aspects and candidate biomarkers for rapid-cycling in bipolar disorder: A systematic review.

    Science.gov (United States)

    Buoli, Massimiliano; Serati, Marta; Altamura, A Carlo

    2017-12-01

    Rapid-cycling bipolar disorder represents a frequent severe subtype of illness which has been associated with poor response to pharmacological treatment. Aim of the present article is to provide an updated review of biological markers associated with rapid-cycling bipolar disorder. A research in the main database sources has been conducted to identify relevant papers about the topic. Rapid-cycling bipolar disorder patients seem to have a more frequent family history for bipolar spectrum disorders (d range: 0.44-0.74) as well as an increased susceptibility to DNA damage or mRNA hypo-transcription (d range: 0.78-1.67) than non rapid-cycling ones. A susceptibility to hypothyroidism, which is exacerbated by treatment with lithium, is possible in rapid-cycling bipolar disorder, but further studies are needed to draw definitive conclusions. Rapid-cycling bipolar patients might have more insuline resistance as well as more severe brain changes in frontal areas (d range: 0.82-0.94) than non rapid-cycling ones. Many questions are still open about this topic. The first is whether the rapid-cycling is inheritable or is more generally the manifestation of a severe form of bipolar disorder. The second is whether some endocrine dysfunctions (diabetes and hypothyroidism) predispose to rapid-cycling or rapid-cycling is the consequence of drug treatment or medical comorbidities (e.g. obesity). Copyright © 2017 Elsevier B.V. All rights reserved.

  19. On-Orbit Propulsion OMS/RCS

    Science.gov (United States)

    Hurlbert, Eric A.

    2001-01-01

    This slide presentation reviews the Space Shuttle's On-Orbit Propulsion systems: the Orbital Maneuvering System (OMS) and the Reaction Control System (RCS). The functions of each of the systems is described, and the diagrams of the systems are presented. The OMS/RCS thruster is detailed and a trade study comparison of non-toxic propellants is presented.

  20. Rapid Cycle Amine (RCA) 3.0 System Development

    Science.gov (United States)

    Chullen, Cinda; Campbell, Colin; Papale, William; Hawes, Kevin; Wichowski, Robert

    2015-01-01

    The Rapid Cycle Amine (RCA) 3.0 system is currently under development by NASA, the Lyndon B. Johnson Space Center (JSC) in conjunction with United Technologies Corporation Aerospace Systems (UTAS). The RCA technology is a new carbon dioxide (CO2) and humidity removal system that has been baselined for the Advanced Extravehicular Mobility Unit (AEMU) Portable Life Support System. The evolution of the RCA development has progressed through several iterations of technology readiness levels including RCA 1.0, RCA 2.0, and RCA 3.0 test articles. The RCA is an advancement over currently technologies due to its unique regeneration capability. The RCA is capable of simultaneously removing CO2 and humidity from an influent air steam and subsequent regeneration when exposed to a vacuum source. The RCA technology uses two solid amine sorbent beds in an alternating fashion to adsorb CO2 and water (uptake mode) and desorb CO2 and water (regeneration mode) at the same time. The two beds operate in an efficient manner so that while one bed is in the uptake mode, the other is in the regeneration mode, thus continuously providing an on-service sorbent bed by which CO2 and humidity may be removed. The RCA 2.0 and 3.0 test articles were designed with a novel valve assembly which allows for switching between uptake and regeneration modes with only one moving part while minimizing gas volume losses to the vacuum source by means of an internal pressure equalization step during actuation. The RCA technology also is low power, small, and has performed extremely well in all development testing thus far. A final design was selected for the RCA 3.0, fabricated, assembled, and performance tested in 2014 with delivery to NASAJSC in January 2015. This paper will provide an overview on the RCA 3.0 system design and results of pre-delivery testing with references to the development of RCA 1.0 and RCA 2.0.

  1. Preliminary tests of a second harmonic rf system for the intense pulsed neutron source synchrotron

    International Nuclear Information System (INIS)

    Norem, J.; Brandeberry, F.

    1983-01-01

    The Rapid Cycling Synchrotron (RCS) of the Intense Pulsed Neutron Source (IPNS) operating at Argonne National Laboratory is presently producing intensities of 2 to 2.5 x 10 12 protons per pulse (ppp) with the addition of a new ion source. This intensity is close to the space charge limit of the machine, estimated at approx. 3 x 10 12 ppp, depending somewhat on the available aperture. Accelerator improvements are being directed at (1) increasing beam intensities for neutron science, (2) lowering acceleration losses to minimize activation, and (3) gaining better control of the beam so that losses can be made to occur when and where they can be most easily controlled. We are now proposing a third cavity for the RF system which would provide control of the longitudinal bunch shape during the cycle which would permit raising the effective space charge limit of the accelerator and reducing losses by providing more RF voltage at maximum acceleration. This paper presents an outline of the expected benefits together with recent results obtained during low energy operation with one of the two existing cavities operating at the second harmonic

  2. CRY2 is associated with rapid cycling in bipolar disorder patients.

    Directory of Open Access Journals (Sweden)

    Louise K Sjöholm

    2010-09-01

    Full Text Available Bipolar disorder patients often display abnormalities in circadian rhythm, and they are sensitive to irregular diurnal rhythms. CRY2 participates in the core clock that generates circadian rhythms. CRY2 mRNA expression in blood mononuclear cells was recently shown to display a marked diurnal variation and to respond to total sleep deprivation in healthy human volunteers. It was also shown that bipolar patients in a depressive state had lower CRY2 mRNA levels, nonresponsive to total sleep deprivation, compared to healthy controls, and that CRY2 gene variation was associated with winter depression in both Swedish and Finnish cohorts.Four CRY2 SNPs spanning from intron 2 to downstream 3'UTR were analyzed for association to bipolar disorder type 1 (n = 497, bipolar disorder type 2 (n = 60 and bipolar disorder with the feature rapid cycling (n = 155 versus blood donors (n = 1044 in Sweden. Also, the rapid cycling cases were compared with bipolar disorder cases without rapid cycling (n = 422. The haplotype GGAC was underrepresented among rapid cycling cases versus controls and versus bipolar disorder cases without rapid cycling (OR = 0.7, P = 0.006-0.02, whereas overrepresentation among rapid cycling cases was seen for AAAC (OR = 1.3-1.4, P = 0.03-0.04 and AGGA (OR = 1.5, P = 0.05. The risk and protective CRY2 haplotypes and their effect sizes were similar to those recently suggested to be associated with winter depression in Swedes.We propose that the circadian gene CRY2 is associated with rapid cycling in bipolar disorder. This is the first time a clock gene is implicated in rapid cycling, and one of few findings showing a molecular discrimination between rapid cycling and other forms of bipolar disorder.

  3. Comparison of treatment outcome using two definitions of rapid cycling in subjects with bipolar II disorder.

    Science.gov (United States)

    Amsterdam, Jay D; Lorenzo-Luaces, Lorenzo; DeRubeis, Robert J

    2017-02-01

    We examined differences in treatment outcome between Diagnostic and Statistical Manual Fourth Edition (DSM-IV)-defined rapid cycling and average lifetime-defined rapid cycling in subjects with bipolar II disorder. We hypothesized that, compared with the DSM-IV definition, the average lifetime definition of rapid cycling may better identify subjects with a history of more mood lability and a greater likelihood of hypomanic symptom induction during long-term treatment. Subjects ≥18 years old with a bipolar II major depressive episode (n=129) were categorized into DSM-IV- and average lifetime-defined rapid cycling and prospectively treated with either venlafaxine or lithium monotherapy for 12 weeks. Responders (n=59) received continuation monotherapy for six additional months. These exploratory analyses found moderate agreement between the two rapid-cycling definitions (κ=0.56). The lifetime definition captured subjects with more chronic courses of bipolar II depression, whereas the DSM-IV definition captured subjects with more acute symptoms of hypomania. There was no difference between rapid-cycling definitions with respect to the response to acute venlafaxine or lithium monotherapy. However, the lifetime definition was slightly superior to the DSM-IV definition in identifying subjects who went on to experience hypomanic symptoms during continuation therapy. Although sample sizes were limited, the findings suggest that the lifetime definition of rapid cycling may identify individuals with a chronic rapid-cycling course and may also be slightly superior to the DSM-IV definition in identifying individuals with hypomania during relapse-prevention therapy. These findings are preliminary in nature and need replication in larger, prospective, bipolar II studies. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Preliminary Research on RCS Using DGTD

    Directory of Open Access Journals (Sweden)

    Yang Qian

    2015-06-01

    Full Text Available Discontinuous Galerkin Time Domain (DGTD method appears to be very promising which combines the advantages of unstructured mesh in Finite Element Time Domain (FETD and explicit scheme in Finite Difference Time Domain (FDTD. This paper first describes principle of DGTD base on vector basis function. Secondly, Specific method for incident plane wave is given for scattering problem. At last, the monostatic Radar Cross Section (RCS of PEC sphere, medium sphere and the PEC bullet are computed by DGTD method. The numerical results illustrate the feasibility and correctness of the presented scheme. The study of this paper is a foundation for analyzing the RCS of complex target.

  5. Applications and control of air conditioning systems using rapid cycling to modulate capacity

    Energy Technology Data Exchange (ETDEWEB)

    Poort, M.J.; Bullard, C.W. [Department of Mechanical and Industrial Engineering, Air Conditioning and Refrigeration Center, University of Illinois, 1206 W. Green St., Urbana, IL 61801 (United States)

    2006-08-15

    Rapid cycling the compressor of an air conditioning or refrigeration system can be used to modulate capacity, thus offering an alternative to a variable speed compressor. This paper explores design tradeoffs to optimize rapid cycling performance based on experimental results using two different evaporators and changing other components of an air conditioning system. Rapid cycling has inherent compressor lift penalties associated with larger mass flow rates, which need to be minimized. Preventing dryout (superheating) in the evaporator during the off cycle, a major penalty as cycles are lengthened, is also important. Evaporator dryout is minimized by increasing the refrigerant side area and reducing off cycle drainage. Combining a flash gas bypass with a suction line heat exchanger was found to maximize performance during the off cycle while allowing increased cycle lengths without incurring major penalties. (author)

  6. Reliability and validity of four alternative definitions of rapid-cycling bipolar disorder.

    Science.gov (United States)

    Maj, M; Pirozzi, R; Formicola, A M; Tortorella, A

    1999-09-01

    This study tested the reliability and validity of four definitions of rapid cycling. Two trained psychiatrists, using the Schedule for Affective Disorders and Schizophrenia, independently assessed 210 patients with bipolar disorder. They checked whether each patient met four definitions of rapid cycling: one consistent with DSM-IV criteria, one waiving criteria for duration of affective episodes, one waiving such criteria and requiring at least one switch from mania to depression or vice versa during the reference year, and one waiving duration criteria and requiring at least 8 weeks of fully symptomatic affective illness during the reference year. The interrater reliability was calculated by Cohen's kappa statistic. Patients who met each definition according to both psychiatrists were compared to those who did not meet any definition (nonrapid-cycling group) on demographic and clinical variables. All patients were followed up for 1 year. Kappa values were 0.93, 0.73, 0.75, and 0.80, respectively, for the four definitions of rapid cycling. The groups meeting the second and third definitions included significantly more female and bipolar II patients than did the nonrapid-cycling group. Those two groups also had the lowest proportion of patients with a favorable lithium prophylaxis outcome and the highest stability of the rapid-cycling pattern on follow-up. The four groups of rapid-cycling patients did not differ significantly among themselves on any of the assessed variables. The expression "rapid cycling" encompasses a spectrum of conditions. The DSM-IV definition, although quite reliable, covers only part of this spectrum, and the conditions that are excluded are very typical in terms of key validators and are relatively stable over time.

  7. Synchrotron radiation

    CERN Document Server

    Kunz, C

    1974-01-01

    The production of synchrotron radiation as a by-product of circular high-energy electron (positron) accelerators or storage rings is briefly discussed. A listing of existing or planned synchrotron radiation laboratories is included. The following properties are discussed: spectrum, collimation, polarization, and intensity; a short comparison with other sources (lasers and X-ray tubes) is also given. The remainder of the paper describes the experimental installations at the Deutsches Elektronen-Synchrotron (DESY) and DORIS storage rings, presents a few typical examples out of the fields of atomic, molecular, and solid-state spectroscopy, and finishes with an outlook on the use of synchrotron radiation in molecular biology. (21 refs).

  8. Proceedings of the workshop on LAMPF II synchrotron

    International Nuclear Information System (INIS)

    Cooper, R.K.

    1983-01-01

    Topics covered at the workshop include: considerations for a staged approach to synchrotron construction; consideration of energy and cost for a kaon and/or antiproton factory; changing the transition energy in the main ring for the Fermilab antiproton beam; a lattice with 50% undispersed straight sections; bunch width considerations in a stretcher ring; a self-consistent longitudinal distribution; rapid-cycling tuned rf cavity for synchrotron use; considerations on a high-shunt impedance tunable RF cavity; rotating condensers; low extraction from the stretcher ring; an antiproton source for LAMPF II; synchrotron magnet circuit; power supply and ring magnet options; and notes for a kaon factory design

  9. Rapid cycling bipolar affective disorder and recurrent strokes secondary to high blood homocysteine.

    Science.gov (United States)

    Awara, Mahmoud A; Zahid, Shazia; Elnenaei, Manal O

    2014-10-01

    The interface between psychiatric disorders and organicity has been a matter for contentious debate. To report an interesting clinical case of moderate homocystinuria presenting with significant psychiatric and neurological deficits. A case report highlighting the impact of homocystinuria on producing intractable rapid cycling bipolar affective disorder. Homocystinuria is a frequently missed cause for treatment-resistant bipolar affective disorder.

  10. Synchrotron radiation

    International Nuclear Information System (INIS)

    Nave, C.; Quinn, P.; Blake, R.J.

    1988-01-01

    The paper on Synchrotron Radiation contains the appendix to the Daresbury Annual Report 1987/88. The appendix is mainly devoted to the scientific progress reports on the work at the Synchrotron Radiation Source in 1987/8. The parameters of the Experimental Stations and the index to the Scientific Reports are also included in the appendix. (U.K.)

  11. Synchrotron light

    International Nuclear Information System (INIS)

    2001-01-01

    'Synchrotron Light' is an interactive and detailed introduction to the physics and technology of the generation of coherent radiation from accelerators as well as to its widespread high-tech applications in science, medicine and engineering. The topics covered are the interaction of light and matter, the technology of synchrotron light sources, spectroscopy, imaging, scattering and diffraction of X-rays, and applications to materials science, biology, biochemistry, medicine, chemistry, food and pharmaceutical technology. All synchrotron light facilities are introduced with their home-page addresses. 'Synchrotron Light' provides an instructive and comprehensive multimedia learning tool for students, experienced practitioners and novices wishing to apply synchrotron radiation in their future work. Its multiple-entry points permit an easy exploration of the CD-Rom according to the users knowledge and interest. 2-D and 3-D animations and virtual reconstruction with computer-generated images guide visitors into the scientific and technical world of a synchrotron and into the applications of synchrotron radiation. This bilingual (English and French) CD-Rom can be used for self-teaching and in courses at various levels in physics, chemistry, engineering, and biology. (author)

  12. Synchrotron radiation

    International Nuclear Information System (INIS)

    Helliwell, J.R.; Walker, R.P.

    1985-01-01

    A detailed account of the research work associated with the Synchrotron Radiation Source at Daresbury Laboratory, United Kingdom, in 1984/85, is presented in the Appendix to the Laboratory's Annual Report. (U.K.)

  13. Synchrotron radiation

    International Nuclear Information System (INIS)

    Hallmeier, K.H.; Meisel, A.; Ranft, J.

    1982-01-01

    The physical background and the properties of synchrotron radiation are described. The radiation offers many useful applications in the fields of spectroscopy and structural investigations. Some examples are given

  14. Synchrotron radiation

    International Nuclear Information System (INIS)

    Knotek, M.L.

    1987-01-01

    Synchrotron radiation has had a revolutionary effect on a broad range of scientific studies, from physics, chemistry and metallurgy to biology, medicine and geoscience. The situation during the last decade has been one of very rapid growth, there is a great vitality to the field and a capability has been given to a very broad range of scientific disciplines which was undreamed of just a decade or so ago. Here we will discuss some of the properties of synchrotron radiation that makes it so interesting and something of the sources in existence today including the National Synchrotron Light Source (NSLS). The NSLS is one of the new facilities built specifically for synchrotron radiation research and the model that was developed there for involvement of the scientific community is a good one which provides some good lessons for these facilities and others

  15. Synchrotron radiation

    International Nuclear Information System (INIS)

    Poole, M.W.; Lea, K.R.

    1982-01-01

    A report is given on the work involving the Synchrotron Radiation Division of the Daresbury Laboratory during the period January 1981 - March 1982. Development of the source, beamlines and experimental stations is described. Progress reports from individual investigators are presented which reveal the general diversity and interdisciplinary nature of the research which benefits from access to synchrotron radiation and the associated facilities. Information is given on the organisation of the Division and publications written by the staff are listed. (U.K.)

  16. Synchrotron radiation

    International Nuclear Information System (INIS)

    Norman, D.; Walker, R.P.; Durham, P.J.; Ridley, P.A.

    1986-01-01

    The paper on synchrotron radiation is the appendix to the Daresbury (United Kingdom) annual report, 1985/86. The bulk of the volume is made up of the progress reports for the work carried out during the year under review using the Synchrotron Radiation Source (SRS) at Daresbury. The Appendix also contains: the scientific programmes at the the SRS, progress on beamlines, instrumentation and computing developments, and activities connected with accelerator development. (U.K.)

  17. Transient modeling of an air conditioner with a rapid cycling compressor and multi-indoor units

    International Nuclear Information System (INIS)

    Zhang Weijiang; Zhang Chunlu

    2011-01-01

    Rapid cycling the compressor is an alternative of the variable speed compressor to modulate the capacity of refrigeration systems for the purpose of energy saving at part-load conditions. The multi-evaporator air conditioner combined with the rapid cycling compressor brings difficulties in control design because of the sophisticated system physics and dynamics. In this paper the transient model of a multi-split air conditioner with a digital scroll compressor is developed for predicting the system transients under performance modulations. The predicted cycling dynamics are in good agreement with the experimental data. Based on the validated model, the impact of compressor idle power and cycle period to the part load performance is discussed.

  18. Transient modeling of an air conditioner with a rapid cycling compressor and multi-indoor units

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Wei-Jiang [Institute of Refrigeration and Cryogenics, Shanghai Jiaotong University, Shanghai 200240 (China); Zhang, Chun-Lu [College of Mechanical Engineering, Tongji University, 4800 Cao An Highway, Shanghai 201804 (China)

    2011-01-15

    Rapid cycling the compressor is an alternative of the variable speed compressor to modulate the capacity of refrigeration systems for the purpose of energy saving at part-load conditions. The multi-evaporator air conditioner combined with the rapid cycling compressor brings difficulties in control design because of the sophisticated system physics and dynamics. In this paper the transient model of a multi-split air conditioner with a digital scroll compressor is developed for predicting the system transients under performance modulations. The predicted cycling dynamics are in good agreement with the experimental data. Based on the validated model, the impact of compressor idle power and cycle period to the part load performance is discussed. (author)

  19. Transient modeling of an air conditioner with a rapid cycling compressor and multi-indoor units

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Weijiang [Institute of Refrigeration and Cryogenics, Shanghai Jiaotong University, Shanghai 200240 (China); Zhang Chunlu, E-mail: chunlu.zhang@carrier.utc.co [College of Mechanical Engineering, Tongji University, 4800 Cao An Highway, Shanghai 201804 (China)

    2011-01-15

    Rapid cycling the compressor is an alternative of the variable speed compressor to modulate the capacity of refrigeration systems for the purpose of energy saving at part-load conditions. The multi-evaporator air conditioner combined with the rapid cycling compressor brings difficulties in control design because of the sophisticated system physics and dynamics. In this paper the transient model of a multi-split air conditioner with a digital scroll compressor is developed for predicting the system transients under performance modulations. The predicted cycling dynamics are in good agreement with the experimental data. Based on the validated model, the impact of compressor idle power and cycle period to the part load performance is discussed.

  20. Elevated levels of plasma brain derived neurotrophic factor in rapid cycling bipolar disorder patients

    DEFF Research Database (Denmark)

    Munkholm, Klaus; Pedersen, Bente Klarlund; Kessing, Lars Vedel

    2014-01-01

    Impaired neuroplasticity may be implicated in the pathophysiology of bipolar disorder, involving peripheral alterations of the neurotrophins brain derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3). Evidence is limited by methodological issues and is based primarily on case-control desi......Impaired neuroplasticity may be implicated in the pathophysiology of bipolar disorder, involving peripheral alterations of the neurotrophins brain derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3). Evidence is limited by methodological issues and is based primarily on case......-control designs. The aim of this study was to investigate whether BDNF and NT-3 levels differ between patients with rapid cycling bipolar disorder and healthy control subjects and whether BDNF and NT-3 levels alter with affective states in rapid cycling bipolar disorder patients. Plasma levels of BDNF and NT-3......, levels of BDNF were significantly elevated in bipolar disorder patients in euthymic- (pdifference in BDNF levels...

  1. JHF synchrotrons

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The Japan Hadron Facility (JHF) consists of two synchrotrons and an injector linac. First, we will present a brief review of the specifications and lattice of the synchrotrons; one is 3 GeV booster and the other is 50 GeV main ring. Secondly, some detailed results of design study will be discussed, together with the present status of the R and D programs in progress. Among them, an estimate of beam loss is one of critical issues in beam dynamics. The development of a high gradient RF cavity is also crucial for a high intensity machine. (author)

  2. Correlates of historical suicide attempt in rapid-cycling bipolar disorder: a cross-sectional assessment.

    Science.gov (United States)

    Gao, Keming; Tolliver, Bryan K; Kemp, David E; Ganocy, Stephen J; Bilali, Sarah; Brady, Kathleen L; Findling, Robert L; Calabrese, Joseph R

    2009-07-01

    A rapid-cycling course in bipolar disorder has previously been identified as a risk factor for attempted suicide. This study investigated factors associated with suicide attempts in patients with rapid-cycling bipolar I or II disorder. Cross-sectional data at the initial assessment of patients who were enrolled into 4 clinical trials were used to study the factors associated with suicide attempt. An extensive clinical interview and the Mini-International Neuropsychiatric Interview were used to ascertain DSM-IV diagnoses of rapid-cycling bipolar disorder, substance use disorders, anxiety disorders, psychosis, and other clinical variables. Chi-square, t test, and logistic regression or Poisson regression were used to analyze the data where appropriate, with odds ratios (ORs) for relative risk estimate. The data were collected from September 1995 to June 2005. In a univariate analysis, 41% of 561 patients had at least 1 lifetime suicide attempt. Earlier age of depression onset, bipolar I subtype, female sex, unmarried status, and a history of drug use disorder, panic disorder, sexual abuse, and psychosis were associated with significantly higher rates of attempted suicide (all p drug abuse (OR = 1.62, p = .0317) were independent predictors for increased risk of attempted suicide. However, white race was associated with a lower risk for suicide attempt (OR = 0.47, p = .0160). Psychosis during depression (p = .0003), bipolar I subtype (p = .0302), and physical abuse (p = .0195) were associated with increased numbers of suicide attempts by 248%, 166%, and 162%, respectively; white race was associated with a 60% decrease in the number of suicide attempts (p = .0320). In this highly comorbid group of patients with rapid-cycling bipolar disorder, 41% had at least 1 suicide attempt. Among the demographics, female sex was positively associated, but white race was negatively associated, with the risk for suicide attempt. Independent clinical variables for increased risk and

  3. Psychiatric and clinical correlates of rapid cycling bipolar disorder: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Alexandre D. Gigante

    2016-01-01

    Full Text Available Objective: Rapid cycling (RC is a feature of bipolar disorder (BD that has been associated with worse outcome and more severe disability. Our goal was to investigate the association of demographic and clinical factors with RC. Methods: We compared RC and non-rapid cycling (NRC BD patients from the Brazilian Research Network in Bipolar Disorder (BRN-BD regarding age at onset of BD; total number of episodes; previous number of manic, depressive, mixed, and hypomanic episodes; polarity of the first episode; gender; number of suicide attempts; number of lifetime hospitalizations and lifetime history of at least one hospitalization; family history of mood disorder; clinical comorbidities such as hypothyroidism, hyperthyroidism, seizures; and current use of medications such as lithium, anticonvulsants, antipsychotics, and antidepressants. Results: We studied 577 patients and found that 100 (17.3% met the criteria for RC in the year before the investigation. RC patients had earlier age at onset, longer duration of disease, more lifetime depressive and manic episodes, higher number of suicide attempts, and higher rate antidepressant use. Conclusion: The presence of RC in the previous year was associated with specific clinical characteristics closely related to worse outcome in the course of BD.

  4. Metal radomes for reduced RCS performance

    Science.gov (United States)

    Wahid, M.; Morris, S. B.

    A frequency selective surface (FSS) comprising a square grid and a hexagonal array of disks is proposed as a means of reducing the Radar Cross Section (RCS) of a radar bay over a wide (2 GHz to 14.6 GHz) frequency bandwidth. Results are presented in terms of transmission loss for an 'A'-type sandwich radome consisting of two FSS layers for normal and non-normal incidence. A single FSS layer on a GRP flat panel is also considered. Good agreement is found between the predicted and measured results. The proposed FSS shows good performance and is relatively insensitive to angle of incidence between 3.8 GHz and 10.1 GHz. Predicted Insertion Phase Delay (IPD) and cross-polar performances are also given. Parametric studies have indicated the versatility of the proposed structure.

  5. Analysis of effect of late water injection on RCS repressurization

    International Nuclear Information System (INIS)

    Tao Jun; Cao Xuewu

    2011-01-01

    Effect of late water injection on RCS repressurization during high pressure severe accident sequence in a typical PWR was analyzed. As the results shown, late water injection could increase RCS pressure when RPV failed without RCS passive depressurization. Especially in the condition of opening one PORV, RCS pressure could reach high pressure limit when RPV failed and the risk of HPME and DCH was dramatically increased. Integrity of containment could be threatened. However, in the condition of RCS passive depressurization induced by pressurizer surge line creep failure, RCS pressure could be decreased to very low level even only one PORV was opened and two trains of emergency core cooling were implemented. The risk of HPME and DCH was eliminated. The more PORVs were opened, the faster accident progression was and the earlier RPV failed. RCS pressure was a little higher when PRV failed if two trains of emergency core cooling was implemented comparing with the condition with only one train of emergency core cooling. However the time of RPV failure was obviously delayed. From the point of delaying RPV failure and preventing containment early failure of view, the optimized late water injection was opening three PORVs and implementing two trains of emergency core cooling. (authors)

  6. Inferior ectopic pupil and typical ocular coloboma in RCS rats.

    Science.gov (United States)

    Tsuji, Naho; Ozaki, Kiyokazu; Narama, Isao; Matsuura, Tetsuro

    2011-08-01

    Ocular coloboma is sometimes accompanied by corectopia in humans and therefore ectopic pupil may indicate ocular coloboma in experimental animals. The RCS strain of rats has a low incidence of microphthalmia. We found that inferior ectopic pupil is associated exclusively with small-sized eyes in this strain. The objective of the current study was to evaluate whether inferior ectopic pupil is associated with iridal coloboma and other types of ocular coloboma in RCS rats. Both eyes of RCS rats were examined clinically, and those with inferior ectopic pupils underwent morphologic and morphometric examinations. In a prenatal study, coronal serial sections of eyeballs from fetuses at gestational day 16.5 were examined by using light microscopy. Ectopic pupils in RCS rats were found exclusively in an inferior position, where the iris was shortened. Fundic examination revealed severe chorioretinal coloboma in all cases of inferior ectopic pupil. The morphologic characteristics closely resembled those of chorioretinal coloboma in humans. Histopathologic examination of primordia showed incomplete closure of the optic fissure in 4 eyeballs of RCS fetuses. Neither F(1) rats nor N(2) (progeny of RCS × BN matings) displayed any ocular anomalies, including ectopic pupils. The RCS strain is a suitable model for human ocular coloboma, and inferior ectopic pupil appears to be a strong indicator of ocular coloboma.

  7. Synchrotron Radiation

    International Nuclear Information System (INIS)

    Asfour, F.I

    2000-01-01

    Synchrotron light is produced by electron accelerators combined with storage rings. This light is generated over a wide spectral region; from infra-red (IR) through the visible and vacuum ultraviolet (VUV), and into the X-ray region. For relativistic electrons (moving nearly with the speed of light), most radiation is concentrated in a small cone with an opening angle of 1/gamma(some 0.1 to 1 milliradian),where gamma is the electron energy in units of rest energy (typically 10 3 -10 4 ). In synchrotron radiation sources (storage rings) highly relativistic electrons are stored to travel along a circular path for many hours. Radiation is caused by transverse acceleration due to magnetic forces(bending magnets). The radiation is emitted in pulses of 10-20 picosecond, separated by some 2 nanosecond or longer separation

  8. Ultra-wideband RCS reduction using novel configured chessboard metasurface

    International Nuclear Information System (INIS)

    Zhuang Ya-Qiang; Wang Guang-Ming; Xu He-Xiu

    2017-01-01

    A novel artificial magnetic conductor (AMC) metasurface is proposed with ultra-wideband 180° phase difference for radar cross section (RCS) reduction. It is composed of two dual-resonant AMC cells, which enable a broadband phase difference of 180°±30° from 7.9 GHz to 19.2 GHz to be achieved. A novel strategy is devised by dividing each rectangular grid in a chessboard configuration into four triangular grids, leading to a further reduction of peak bistatic RCS. Both full-wave simulation and measurement results show that the proposed metasurface presents a good RCS reduction property over an ultra-wideband frequency range. (paper)

  9. Reconsidering Tree Fruit as Candidate Crops Through the Use of Rapid Cycle Crop Breeding Technologies

    Science.gov (United States)

    Graham, Gary Thomas

    2014-01-01

    Tree fruit, although desirable from a crew nutrition and menu diversity perspective, have long been dismissed as candidate crops based on their long juvenile phase, large architecture, low short-term harvest index, and dormancy requirements. Recent developments in Rapid Cycle Crop Breeding (RCCB) have overcome these historical limitations, opening the door to a new era in candidate crop research. Researchers at the United States Department of Agriculture (USDA) have developed FT-construct (Flowering Locus T) dwarf plum lines that have a very short juvenile phase, vine-like architecture, and no obligate dormancy period. In a collaborative research effort, NASA and the USDA are evaluating the performance of these FT-lines under controlled environment conditions relevant to spaceflight.

  10. Radar Cross Section (RCS) Simulation for Wind Turbines

    Science.gov (United States)

    2013-06-01

    wind turbines are unsafe to operate. Also, helical wind turbines generally have less environmental concerns such as killing birds , especially in...SECTION (RCS) SIMULATION FOR WIND TURBINES by Cuong Ton June 2013 Thesis Advisor: David C. Jenn Second Reader: Ric Romero THIS PAGE...TITLE AND SUBTITLE RADAR CROSS SECTION (RCS) SIMULATION FOR WIND TURBINES 5. FUNDING NUMBERS 6. AUTHOR(S) Cuong Ton 7. PERFORMING ORGANIZATION

  11. Synchrotron radiation

    International Nuclear Information System (INIS)

    Farge, Y.

    1982-01-01

    Synchrotron radiation is produced by electrons accelerated near the velocity of light in storage rings, which are used for high energy Physics experiments. The radiation light exhibits a wide spread continuous spectrum ranging from 01 nanometre to radiofrequency. This radiation is characterized by high power (several kilowatts) and intense brightness. The paper recalls the emission laws and the distinctive properties of the radiation, and gives some of the numerous applications in research, such as molecular spectroscopy, X ray diffraction by heavy proteins and X ray microlithography in LVSI circuit making [fr

  12. Synchrotron radiation

    International Nuclear Information System (INIS)

    Pattison, P.; Quinn, P.

    1990-01-01

    This report details the activities in synchrotron radiation and related areas at Daresbury Laboratory during 1989/90. The number and scope of the scientific reports submitted by external users and in-house staff is a reflection of the large amount of scheduled beamtime and high operating efficiency achieved at the Synchrotron Radiation Source (SRS) during the past year. Over 4000 hours of user beam were available, equivalent to about 80% of the total scheduled time. Many of the reports collected here illustrate the increasing technical complexity of the experiments now being carried out at Daresbury. Provision of the appropriate technical and scientific infrastructure and support is a continuing challenge. The development of the Materials Science Laboratory together with the existing Biological Support Laboratory will extend the range of experiments which can be carried out on the SRS. This will particularly facilitate work in which the sample must be prepared or characterised immediately before or during an experiment. The year 1989/90 has also seen a substantial upgrade of several stations, especially in the area of x-ray optics. Many of the advantages of the High Brightness Lattice can only be exploited effectively with the use of focusing optics. As the performance of these stations improves, the range of experiments which are feasible on the SRS will be extended significantly. (author)

  13. Resonant circuit which provides dual frequency excitation for rapid cycling of an electromagnet

    Science.gov (United States)

    Praeg, Walter F.

    1984-01-01

    Disclosed is a ring magnet control circuit that permits synchrotron repetition rates much higher than the frequency of the cosinusoidal guide field of the ring magnet during particle acceleration. the control circuit generates cosinusoidal excitation currents of different frequencies in the half waves. During radio frequency acceleration of the particles in the synchrotron, the control circuit operates with a lower frequency cosine wave and thereafter the electromagnets are reset with a higher frequency half cosine wave. Flat-bottom and flat-top wave shaping circuits maintain the magnetic guide field in a relatively time-invariant mode during times when the particles are being injected into the ring magnets and when the particles are being ejected from the ring magnets.

  14. DECISION-MAKING ALIGNED WITH RAPID-CYCLE EVALUATION IN HEALTH CARE.

    Science.gov (United States)

    Schneeweiss, Sebastian; Shrank, William H; Ruhl, Michael; Maclure, Malcolm

    2015-01-01

    Availability of real-time electronic healthcare data provides new opportunities for rapid-cycle evaluation (RCE) of health technologies, including healthcare delivery and payment programs. We aim to align decision-making processes with stages of RCE to optimize the usefulness and impact of rapid results. Rational decisions about program adoption depend on program effect size in relation to externalities, including implementation cost, sustainability, and likelihood of broad adoption. Drawing on case studies and experience from drug safety monitoring, we examine how decision makers have used scientific evidence on complex interventions in the past. We clarify how RCE alters the nature of policy decisions; develop the RAPID framework for synchronizing decision-maker activities with stages of RCE; and provide guidelines on evidence thresholds for incremental decision-making. In contrast to traditional evaluations, RCE provides early evidence on effectiveness and facilitates a stepped approach to decision making in expectation of future regularly updated evidence. RCE allows for identification of trends in adjusted effect size. It supports adapting a program in midstream in response to interim findings, or adapting the evaluation strategy to identify true improvements earlier. The 5-step RAPID approach that utilizes the cumulating evidence of program effectiveness over time could increase policy-makers' confidence in expediting decisions. RCE enables a step-wise approach to HTA decision-making, based on gradually emerging evidence, reducing delays in decision-making processes after traditional one-time evaluations.

  15. Plant Growth and Development: An Outline for a Unit Structured Around the Life Cycle of Rapid-Cycling Brassica Rapa.

    Science.gov (United States)

    Becker, Wayne M.

    This outline is intended for use in a unit of 10-12 lectures on plant growth and development at the introductory undergraduate level as part of a course on organismal biology. The series of lecture outlines is structured around the life cycle of rapid-cycling Brassica rapa (RCBr). The unit begins with three introductory lectures on general plant…

  16. Remission of classic rapid cycling bipolar disorder with levothyroxine augmentation therapy in a male patient having clinical hypothyroidism

    Directory of Open Access Journals (Sweden)

    Chen PH

    2015-02-01

    Full Text Available Pao-Huan Chen, Yu-Jui Huang Department of Psychiatry, Taipei Medical University Hospital, Taipei, Taiwan Abstract: The literature suggests that patients with bipolar disorder, particularly females, have greater vulnerability to rapid cycling features. Levothyroxine therapy might be potentially useful to attenuate mood instability in this patient group. In contrast, reports on male patients remain limited and controversial. Herein, we report a 32-year-old male patient who had bipolar 1 disorder for 12 years who developed a breakthrough rapid cycling course and first-onset clinical hypothyroidism at the age of 31 years during lithium therapy. After levothyroxine augmentation therapy was introduced, the patient had remission from the rapid cycling illness course along with normalization of serum levels of free T4 and thyroid stimulating hormone in the subsequent year. This observation suggested that investigation of both levothyroxine pharmacology and thyroid pathology in male patients with rapid cycling bipolar disorder might be of much value. Keywords: mood disorder, therapy, thyroid hormone

  17. RCS Diversity of Electromagnetic Wave Carrying Orbital Angular Momentum.

    Science.gov (United States)

    Zhang, Chao; Chen, Dong; Jiang, Xuefeng

    2017-11-13

    An electromagnetic (EM) wave with orbital angular momentum (OAM) has a helical wave front, which is different from that of the plane wave. The phase gradient can be found perpendicular to the direction of propagation and proportional to the number of OAM modes. Herein, we study the backscattering property of the EM wave with different OAM modes, i.e., the radar cross section (RCS) of the target is measured and evaluated with different OAM waves. As indicated by the experimental results, different OAM waves have the same RCS fluctuation for the simple target, e.g., a small metal ball as the target. However, for complicated targets, e.g., two transverse-deployed small metal balls, different RCSs can be identified from the same incident angle. This valuable fact helps to obtain RCS diversity, e.g., equal gain or selective combining of different OAM wave scattering. The majority of the targets are complicated targets or expanded targets; the RCS diversity can be utilized to detect a weak target traditionally measured by the plane wave, which is very helpful for anti-stealth radar to detect the traditional stealth target by increasing the RCS with OAM waves.

  18. Thermographic Inspections And The Residential Conservation Service Program (RCS)

    Science.gov (United States)

    Ward, Ronald J.

    1983-03-01

    Rhode Islanders Saving Energy (RISE) is a non-profit corporation founded in 1977 to provide Rhode Island residents with a variety of energy conservation services. Since January of 1981, it has been performing energy audits in compliance with the Department of Energy's (DOE) Residential Conservation Service Program (RCS). One aspect of the RCS program is the performance of inspections on energy conservation activities completed according to RCS installation guidelines. This paper will describe both the use and results of thermographic inspections within the RISE program. The primary objective of these inspections has been to assure the quality of the building envelope after completion of retrofit measures. Thermal anamolies have been detected that vary in size, location and probable cause. Approximately 37% of all jobs performed through RISE in conjunction with the RCS program have required remedial work as a result of problems that were identi-fied during the thermographic inspection. This percentage was much higher when infra-red inspections were conducted on "Non-RCS" retrofits. Statistics will be presented that provide an interesting insight on the quality of retrofit work when performed in associa-tion with a constant inspection process.

  19. A Multiple Model SNR/RCS Likelihood Ratio Score for Radar-Based Feature-Aided Tracking

    National Research Council Canada - National Science Library

    Slocumb, Benjamin J; Klusman, III, Michael E

    2005-01-01

    ...) and radar cross section (RCS) for use in narrowband radar tracking. The formulation requires an estimate of the target mean RCS, and a key challenge is the tracking of the mean RCS through significant jumps due to aspect dependencies...

  20. Synchrotron-radiation research

    International Nuclear Information System (INIS)

    Cunningham, J.E.

    1982-01-01

    The use of radiation from synchrotron sources has started a renaissance in materials, physics, chemistry, and biology. Synchrotron radiation has advantages over conventional x rays in that its source brightness is a thousand times greater throughout a continuous energy spectrum, and resonances are produced with specific electron energy levels. Two major synchrotron radiation sources are operated by DOE: the Stanford Synchrotron Radiation Laboratory at SLAC, and the National Synchrotron Light Source at Brookhaven

  1. Synchrotron radiation

    International Nuclear Information System (INIS)

    Seddon, E.A.; Reid, R.J.

    1992-01-01

    Work at the Daresbury SRS has of necessity been interrupted this year (1991/92) due to the incorporation of Wiggler II. However, considerable beamtime was awarded before the shutdown and the major part of this appendix is concerned with the progress reports of the research undertaken then. The reports have been organised under the following broad headings: Molecular Science (19 papers), Surface and Materials Science (169 papers), Biological Science (85 papers), Instrumental and Technique Developments (13 papers) and Accelerator Physics (3 papers). It is hoped that in time the number of contributions on accelerator physics will grow to reflect the in-house activity on, for example, accelerator improvement and design. The research reports are preceded by the Annual Report of the Synchrotron Radiation Facilities Committee, which outlines the research highlights identified by that Committee (also included are details of the current membership of the SRFC and the chairmen of the Beamtime Allocation Panels). Following the reports are the specifications for the beamlines and stations. This year Section 3 contains 289 reports (nearly 100 more than last year) and the number of publications, generated by scientists and engineers who have used or are associated with Daresbury Laboratory facilities, has topped 500 for the first time. (author)

  2. Thermally moderated hollow fiber sorbent modules in rapidly cycled pressure swing adsorption mode for hydrogen purification

    KAUST Repository

    Lively, Ryan P.; Bessho, Naoki; Bhandari, Dhaval A.; Kawajiri, Yoshiaki; Koros, William J.

    2012-01-01

    We describe thermally moderated multi-layered pseudo-monolithic hollow fiber sorbents entities, which can be packed into compact modules to provide small-footprint, efficient H2 purification/CO2 removal systems for use in on-site steam methane reformer product gas separations. Dual-layer hollow fibers are created via dry-jet, wet-quench spinning with an inner "active" core of cellulose acetate (porous binder) and zeolite NaY (69 wt% zeolite NaY) and an external sheath layer of pure cellulose acetate. The co-spun sheath layer reduces the surface porosity of the fiber and was used as a smooth coating surface for a poly(vinyl-alcohol) post-treatment, which reduced the gas permeance through the fiber sorbent by at least 7 orders of magnitude, essentially creating an impermeable sheath layer. The interstitial volume between the individual fibers was filled with a thermally-moderating paraffin wax. CO2 breakthrough experiments on the hollow fiber sorbent modules with and without paraffin wax revealed that the "passively" cooled paraffin wax module had 12.5% longer breakthrough times than the "non-isothermal" module. The latent heat of fusion/melting of the wax offsets the released latent heat of sorption/desorption of the zeolites. One-hundred rapidly cycled pressure swing adsorption cycles were performed on the "passively" cooled hollow fiber sorbents using 25 vol% CO2/75 vol% He (H2 surrogate) at 60 °C and 113 psia, resulting in a product purity of 99.2% and a product recovery of 88.1% thus achieving process conditions and product quality comparable to conventional pellet processes. Isothermal and non-isothermal dynamic modeling of the hollow fiber sorbent module and a traditional packed bed using gPROMS® indicated that the fiber sorbents have sharper fronts (232% sharper) and longer adsorbate breakthrough times (66% longer), further confirming the applicability of the new fiber sorbent approach for H2 purification. © 2012, Hydrogen Energy Publications, LLC

  3. Thermally moderated hollow fiber sorbent modules in rapidly cycled pressure swing adsorption mode for hydrogen purification

    KAUST Repository

    Lively, Ryan P.

    2012-10-01

    We describe thermally moderated multi-layered pseudo-monolithic hollow fiber sorbents entities, which can be packed into compact modules to provide small-footprint, efficient H2 purification/CO2 removal systems for use in on-site steam methane reformer product gas separations. Dual-layer hollow fibers are created via dry-jet, wet-quench spinning with an inner "active" core of cellulose acetate (porous binder) and zeolite NaY (69 wt% zeolite NaY) and an external sheath layer of pure cellulose acetate. The co-spun sheath layer reduces the surface porosity of the fiber and was used as a smooth coating surface for a poly(vinyl-alcohol) post-treatment, which reduced the gas permeance through the fiber sorbent by at least 7 orders of magnitude, essentially creating an impermeable sheath layer. The interstitial volume between the individual fibers was filled with a thermally-moderating paraffin wax. CO2 breakthrough experiments on the hollow fiber sorbent modules with and without paraffin wax revealed that the "passively" cooled paraffin wax module had 12.5% longer breakthrough times than the "non-isothermal" module. The latent heat of fusion/melting of the wax offsets the released latent heat of sorption/desorption of the zeolites. One-hundred rapidly cycled pressure swing adsorption cycles were performed on the "passively" cooled hollow fiber sorbents using 25 vol% CO2/75 vol% He (H2 surrogate) at 60 °C and 113 psia, resulting in a product purity of 99.2% and a product recovery of 88.1% thus achieving process conditions and product quality comparable to conventional pellet processes. Isothermal and non-isothermal dynamic modeling of the hollow fiber sorbent module and a traditional packed bed using gPROMS® indicated that the fiber sorbents have sharper fronts (232% sharper) and longer adsorbate breakthrough times (66% longer), further confirming the applicability of the new fiber sorbent approach for H2 purification. © 2012, Hydrogen Energy Publications, LLC

  4. The Center For Medicare And Medicaid Innovation's blueprint for rapid-cycle evaluation of new care and payment models.

    Science.gov (United States)

    Shrank, William

    2013-04-01

    The Affordable Care Act established the Center for Medicare and Medicaid Innovation to test innovative payment and service delivery models. The goal is to reduce program expenditures while preserving or improving the quality of care provided to beneficiaries of Medicare, Medicaid, and the Children's Health Insurance Program. Central to the success of the Innovation Center is a new, rapid-cycle approach to evaluation. This article describes that approach--setting forth how the Rapid Cycle Evaluation Group aims to deliver frequent feedback to providers in support of continuous quality improvement, while rigorously evaluating the outcomes of each model tested. This article also describes the relationship between the group's work and that of the Office of the Actuary at the Centers for Medicare and Medicaid Services, which plays a central role in the assessment of new models.

  5. Elevated levels of IL-6 and IL-18 in manic and hypomanic states in rapid cycling bipolar disorder patients

    DEFF Research Database (Denmark)

    Munkholm, Klaus; Weikop, Pia; Kessing, Lars Vedel

    2015-01-01

    obtained in affective states of varying polarity during 6-12 months in 37 rapid cycling bipolar disorder patients and compared with repeated measurements in 40 age- and gender matched healthy control subjects, using rigorous laboratory-, clinical- and statistical methodology. Adjusting for demographical...... were to assess alterations of peripheral cytokine levels between affective states in rapid cycling bipolar disorder patients and to compare these with levels in healthy control subjects. In a longitudinal design, repeated measurements of plasma levels of IL-6, IL-10, IL-18, IL-1β and TNF-α were......, clinical- and lifestyle factors, levels of IL-6 (prapid cycling bipolar disorder patients in a manic/hypomanic state, compared with a depressed and a euthymic state. Compared with healthy control subjects, unadjusted levels of IL-6 (p

  6. Verification of the CADRCS RCS tool for NCTR work

    CSIR Research Space (South Africa)

    Botha, L

    2007-03-01

    Full Text Available This paper looks at the suitability of using the CADRCS RCS prediction tool for research into a class of NCTR work where the radar will give a high resolution output of the target, either a High Range Resolution (HRR) plot or Inverse Synthetic...

  7. Study on alumina-alumina brazing for application in vacuum chambers of proton synchrotron

    International Nuclear Information System (INIS)

    Yadav, D.P.; Kaul, R.; Ganesh, P.; Shiroman, Ram; Tiwari, Pragya; Sridhar, R.; Kukreja, L.M.

    2013-01-01

    The paper describes an experimental study to standardize vacuum brazing process to obtain satisfactory high purity alumina brazed joints for application in rapid cycle proton synchrotron machine. Two different brazing routes, adopted for making alumina-alumina brazed joints, included (i) multi-step Mo-Mn metallization and brazing with BVAg-8 alloy and (ii) advanced single-step active brazing with CuSil-ABA alloy. Brazed alumina specimens, prepared by both the routes, yielded ultra high vacuum compatible, helium leak tight and bakeable joints. Active-brazed specimens exhibited satisfactory strength values in tensile and four-point bend tests. Metallized-brazed specimens, although exhibited relatively lower tensile strength than the targeted value, displayed satisfactory flexural strength in four-point bend test. The results of the study demonstrated that active brazing is the simple and cost effective alternative to conventional metallization route for producing satisfactory brazed joints for application in rapid cycle proton synchrotron machine. (author)

  8. Magnetic losses and instabilities in ferrite garnet tuned RF cavities for synchrotrons

    International Nuclear Information System (INIS)

    Shapiro, V.E.

    1994-01-01

    The aim of this paper is to introduce basic notions and elucidate the main features of magnetic losses and nonlinear effects in high power rf cavities with perpendicularly biased ferrite garnet used for varying the frequency in rapid cycling synchrotrons. A method of analysis is developed using a minimum of specific details. Simple formulae and estimates of the trend of magnetic loss, nonlinear frequency shift and possible instabilities in the cavities as a function of rf power level and ferrite garnet parameters are presented. Numerical examples correspond to the TRIUMF KAON Booster synchrotron. (author). 14 refs., 5 figs

  9. Transient protective effect of caspase inhibitors in RCS rat.

    Science.gov (United States)

    Perche, O; Doly, M; Ranchon-Cole, I

    2008-03-01

    In most retinal degenerations in humans and in animal models, photoreceptor cells die by apoptosis. Although the biochemical features are similar in all apoptotic cells, different molecular events lead the cell to death. In the present study we used a rat model of inherited retinal degeneration, the RCS rats, to investigate the involvement of the proteases, caspases and/or calpains, in photoreceptor apoptosis. In the first experiments, rats were untreated or injected intravitreally at post natal day 27 (P27) with the large broad spectrum caspase inhibitor, ZVAD, the calpain inhibitor, MuhPhe, or with the vehicle, DMSO. Retinal status was evaluated at P35 and P42 by electroretinography, morphometry and apoptotic nuclei detection. DMSO and MuhPhe had no effect on RCS retinas as evidenced by equivalent loss of function and equivalent number of apoptotic cells than in untreated group. ZVAD transiently reduced apoptotic cells and preserved photoreceptor function at P35 but not at P42. These results suggest that caspases but not calpains are involved in retinal degeneration in the RCS. In the second experiments, RCS rats were injected twice at P27 and P35 with ZVAD or DMSO. Although ZVAD-treated retinas were preserved at P35 compared to the DMSO controls, the second injection of ZVAD did not extend the preserving effect to P42. Moreover, a single injection of ZVAD at P35 had no preserving effect at P42. All these data taken together suggest that caspases do not play a pivotal role after P35. In a fourth set of experiments, we used specific caspase inhibitors to elucidate which caspase was activated. The caspase-1/4 inhibitor (YVAD) or the caspase-3/7 inhibitor (DEVD) were injected intravitreally at P27 and retinal status was evaluated at P35 and P42. Electroretinograms and apoptotic nuclei detection demonstrated that YVAD and DEVD preserved photoreceptors at P35 but not at P42. These results suggest that both caspase-1/4 and caspase-3/7 play a major role in the apoptotic

  10. Synchrotron radiation in Australia

    International Nuclear Information System (INIS)

    Garrett, R.F.

    2002-01-01

    Full text: Synchrotron radiation research in Australia is entering a new era with the commencement of the Australian synchrotron project, which will construct a 3 GeV third generation synchrotron facility at Monash University in Victoria. To date Australian scientists have used overseas facilities, primarily those managed by the Australian Synchrotron Research Program in Japan and the USA. A fast developing and maturing Australian synchrotron user program has developed around these overseas facilities. The field of synchrotron radiation and its importance to a wide range of research will be introduced and Australia's current involvement and facilities will be described. The current status and technical specifications of the Australian synchrotron will be presented. Copyright (2002) Australian X-ray Analytical Association Inc

  11. Numerical simulation of RCS for carrier electronic warfare airplanes

    OpenAIRE

    Yue Kuizhi; Liu Wenlin; Li Guanxiong; Ji Jinzu; Yu Dazhao

    2015-01-01

    This paper studies the radar cross section (RCS) of carrier electronic warfare airplanes. Under the typical naval operations section, the mathematical model of the radar wave’s pitch angle incidence range analysis is established. Based on the CATIA software, considering dynamic deflections of duck wing leading edge flaps, flaperons, horizontal tail, and rudder, as well as aircraft with air-to-air missile, anti-radiation missile, electronic jamming pod, and other weapons, the 3D models of carr...

  12. Fuzzy-4D/RCS for Unmanned Aerial Vehicles

    OpenAIRE

    Olivares Mendez, Miguel Angel; Campoy, Pascual; Mondragon, Ivan F.; Martinez, Carol

    2010-01-01

    Abstract This paper presents an improvement of the cognitive architecture, 4D/RCS, developed by the NIST. This improvement consist of the insertion of Fuzzy Logic cells (FLCs), in different parts and hierarchy levels of the architecture, and the adaptation of this architecture for Unmanned Aerial Vehicles (UAVs). This advance provides an improvement in the functionality of the system based on the uses of the Miguel Olivares’ Fuzzy Software for the definition of the FLCs and its...

  13. Overall view of PLB and OMS / RCS engine thrusting

    Science.gov (United States)

    1983-01-01

    Overall payload bay (PLB) view shows Inertial Upper Stage (IUS) Airborne Support Equipment (ASE) forward frame and aft frame tilt actuator (AFTA) table after IUS Tracking and Data Relay Satellite (TDRS) deploy. Vertical tail and Orbital Maneuvering System (OMS) pods with rear reaction control system (RCS) thruster firing (sidefiring) appears in background against blackness of space. Right right jet firing was photographed from more than 18 meters (60 feet) away in the cabin of the Earth-orbiting Challenger, Orbiter Vehicle (OV) 099.

  14. Injection and capture simulations for a high intensity proton synchrotron

    International Nuclear Information System (INIS)

    Cho, Y.; Lessner, E.; Symon, K.; Univ. of Wisconsin, Madison, WI

    1994-01-01

    The injection and capture processes in a high intensity, rapid cycling, proton synchrotron are simulated by numerical integration. The equations of motion suitable for rapid numerical simulation are derived so as to maintain symplecticity and second-order accuracy. By careful bookkeeping, the authors can, for each particle that is lost, determine its initial phase space coordinates. They use this information as a guide for different injection schemes and rf voltage programming, so that a minimum of particle losses and dilution are attained. A fairly accurate estimate of the space charge fields is required, as they influence considerably the particle distribution and reduce the capture efficiency. Since the beam is represented by a relatively coarse ensemble of macro particles, the authors study several methods of reducing the statistical fluctuations while retaining the fine structure (high intensity modulations) of the beam distribution. A pre-smoothing of the data is accomplished by the cloud-in-cell method. The program is checked by making sure that it gives correct answers in the absence of space charge, and that it reproduces the negative mass instability properly. Results of simulations for stationary distributions are compared to their analytical predictions. The capture efficiency for the rapid-cycling synchrotron is analyzed with respect to variations in the injected beam energy spread, bunch length, and rf programming

  15. Dam methylation participates in the regulation of PmrA/PmrB and RcsC/RcsD/RcsB two component regulatory systems in Salmonella enterica serovar Enteritidis.

    Directory of Open Access Journals (Sweden)

    Sebastián Hernán Sarnacki

    Full Text Available The absence of Dam in Salmonella enterica serovar Enteritidis causes a defect in lipopolysaccharide (LPS pattern associated to a reduced expression of wzz gene. Wzz is the chain length regulator of the LPS O-antigen. Here we investigated whether Dam regulates wzz gene expression through its two known regulators, PmrA and RcsB. Thus, the expression of rcsB and pmrA was monitored by quantitative real-time RT-PCR and Western blotting using fusions with 3×FLAG tag in wild type (wt and dam strains of S. Enteritidis. Dam regulated the expression of both rcsB and pmrA genes; nevertheless, the defect in LPS pattern was only related to a diminished expression of RcsB. Interestingly, regulation of wzz in serovar Enteritidis differed from that reported earlier for serovar Typhimurium; RcsB induces wzz expression in both serovars, whereas PmrA induces wzz in S. Typhimurium but represses it in serovar Enteritidis. Moreover, we found that in S. Enteritidis there is an interaction between both wzz regulators: RcsB stimulates the expression of pmrA and PmrA represses the expression of rcsB. Our results would be an example of differential regulation of orthologous genes expression, providing differences in phenotypic traits between closely related bacterial serovars.

  16. Synchrotron radiation facilities

    CERN Multimedia

    1972-01-01

    Particularly in the past few years, interest in using the synchrotron radiation emanating from high energy, circular electron machines has grown considerably. In our February issue we included an article on the synchrotron radiation facility at Frascati. This month we are spreading the net wider — saying something about the properties of the radiation, listing the centres where synchrotron radiation facilities exist, adding a brief description of three of them and mentioning areas of physics in which the facilities are used.

  17. Effect of natural circulation on RCS depressurization strategy in PWR NPP

    International Nuclear Information System (INIS)

    Zhang Kun; Tong Lili; Cao Xuewu

    2009-01-01

    The natural circulation model of Chinese Qinshan Nuclear Power Plant (NPP) Unit 2 is built using SCDAP/RELAP5 code. Selecting TMLB' accident as the base sequence, this paper analyzes the natural circulation phenomena in high-pressure core melt severe accident. In order to study the effect of natural circulation on RCS depressurization strategy, the accident progressions of RCS depressurization with and without natural circulation are simulated, respectively. According to the results, the natural circulation can delay the initiation of RCS depressurization and the whole accident progression, but it does not evidently influence the results of RCS depressurization. (authors)

  18. Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator.

    Science.gov (United States)

    Casino, Patricia; Miguel-Romero, Laura; Huesa, Juanjo; García, Pablo; García-Del Portillo, Francisco; Marina, Alberto

    2018-01-09

    The RcsCDB phosphorelay system controls an extremely large regulon in Enterobacteriaceae that involves processes such as biofilm formation, flagella production, synthesis of extracellular capsules and cell division. Therefore, fine-tuning of this system is essential for virulence in pathogenic microorganisms of this group. The final master effector of the RcsCDB system is the response regulator (RR) RcsB, which activates or represses multiple genes by binding to different promoter regions. This regulatory activity of RcsB can be done alone or in combination with additional transcriptional factors in phosphorylated or dephosphorylated states. The capacity of RcsB to interact with multiple promoters and partners, either dephosphorylated or phosphorylated, suggests an extremely conformational dynamism for this RR. To shed light on the activation mechanism of RcsB and its implication on promoter recognition, we solved the crystal structure of full-length RcsB from Salmonella enterica serovar Typhimurium in the presence and absence of a phosphomimetic molecule BeF3-. These two novel structures have guided an extensive site-directed mutagenesis study at the structural and functional level that confirms RcsB conformational plasticity and dynamism. Our data allowed us to propose a β5-T switch mechanism where phosphorylation is coupled to alternative DNA binding ways and which highlights the conformational dynamism of RcsB to be so pleiotropic. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  19. A Novel Low RCS Design Method for X-Band Vivaldi Antenna

    Directory of Open Access Journals (Sweden)

    XiaoXiang He

    2012-01-01

    Full Text Available A novel low radar cross-section (RCS design method is proposed, and its application on Vivaldi antenna that covers the entire X band is investigated. According to the difference of the current distribution on the radiator when the antenna radiates or scatters, the shape of the metal radiator is modified, so that maximally 19.2 dBsm RCS reduction is achieved which satisfied radiation performance. Simulated and measured results about gain, S11, and RCS are presented. As a result, the effectiveness of the presented low RCS design method is validated.

  20. The World of Synchrotrons

    Indian Academy of Sciences (India)

    de Ciencias Fisicas,. Universidad Nacional. Autonoma de Mexico. Sameen Ahmed Khan. A summary of results on synchrotron radiation is presented along with notes on its properties and applications. Quantum aspects are briefly mentioned. Synchrotron radiation facilities are described briefly with a detailed coverage of ...

  1. Synchrotron radiation sources

    Energy Technology Data Exchange (ETDEWEB)

    van Steenbergen, A.

    1979-01-01

    As a result of the exponential growth of the utilization of synchrotron radiation for research in the domain of the material sciences, atomic and molecular physics, biology and technology, a major construction activity has been generated towards new dedicated electron storage rings, designed optimally for synchrotron radiation applications, also, expansion programs are underway at the existing facilities, such as DORIS, SPEAR, and VEPP. In this report the basic properties of synchrotron radiation will be discussed, a short overview will be given of the existing and new facilities, some aspects of the optimization of a structure for a synchrotron radiation source will be discussed and the addition of wigglers and undulators for spectrum enhancement will be described. Finally, some parameters of an optimized synchrotron radiation source will be given.

  2. Synchrotron radiation from protons

    International Nuclear Information System (INIS)

    Dutt, S.K.

    1992-12-01

    Synchrotron radiation from protons, though described by the same equations as the radiation from electrons, exhibits a number of interesting features on account of the parameters reached in praxis. In this presentation, we shall point out some of the features relating to (i) normal synchrotron radiation from dipoles in proton machines such as the High Energy Booster and the Superconducting Super Collider; (ii) synchrotron radiation from short dipoles, and its application to light monitors for proton machines, and (iii) synchrotron radiation from undulators in the limit when, the deflection parameter is much smaller than unity. The material for this presentation is taken largely from the work of Hofmann, Coisson, Bossart, and their collaborators, and from a paper by Kim. We shall emphasize the qualitative aspects of synchrotron radiation in the cases mentioned above, making, when possible, simple arguments for estimating the spectral and angular properties of the radiation. Detailed analyses can be found in the literature

  3. Space Shuttle RCS Oxidizer Leak Repair for STS-26

    Science.gov (United States)

    Delventhal, R. A.; Faget, N. M.

    1989-01-01

    Following propellant loading of the Space Shuttle's reaction control system (RCS) for mission STS 26, an oxidizer leak was detected in the left orbital maneuvering system (OMS) pod, where the RCS is located. Subsequent investigation determined that the leak was isolated at a mechanical Dynatube fitting near the RCS nitrogen tetroxide tank. An intense effort was initiated to design, fabricate, and qualify a sealing device to stop the oxidizer leak externally so that the Space Shuttle launch could proceed. It was discovered that sealing devices called clamshells were widely used throughout the petrochemical and power generation industries to stop leaks developed in large diameter pipes which carry steam or other hazardous fluids. These clamshells are available in different diameters and strengths and are placed around the pipe at the location of the leak. A sealing compound is then injected under high pressure into the clamshell to stop the leak. This technology was scaled down and applied to the problem of stopping the leak on the Orbiter, which was on a half-inch diameter line in a nearly inaccessible location. Many obstacles had to be overcome such as determining that the sealing material would be compatible with the nitrogen tetroxide and ensuring that the clamshell would actually fit around the Dynatube fitting without interfering with other lines which were in close proximity. The effort at the NASA Johnson Space Center included materials compatibility testing of several sealants, design of a clamshell to fit in the confined compartment, and manufacture and qualification of the flight hardware. A clamshell was successfully placed around the Dynatube fitting on the Orbiter and the oxidizer leak was terminated. Then it was decided to apply this technology further and design clamshells for other mechanical fittings onboard the Orbiter and develop sealing compounds which will be compatible with fuels such as monomethyl hydrazine (MMH). The potential exists for

  4. Proteomic profiling of early degenerative retina of RCS rats.

    Science.gov (United States)

    Zhu, Zhi-Hong; Fu, Yan; Weng, Chuan-Huang; Zhao, Cong-Jian; Yin, Zheng-Qin

    2017-01-01

    To identify the underlying cellular and molecular changes in retinitis pigmentosa (RP). Label-free quantification-based proteomics analysis, with its advantages of being more economic and consisting of simpler procedures, has been used with increasing frequency in modern biological research. Dystrophic RCS rats, the first laboratory animal model for the study of RP, possess a similar pathological course as human beings with the diseases. Thus, we employed a comparative proteomics analysis approach for in-depth proteome profiling of retinas from dystrophic RCS rats and non-dystrophic congenic controls through Linear Trap Quadrupole - orbitrap MS/MS, to identify the significant differentially expressed proteins (DEPs). Bioinformatics analyses, including Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway annotation and upstream regulatory analysis, were then performed on these retina proteins. Finally, a Western blotting experiment was carried out to verify the difference in the abundance of transcript factor E2F1. In this study, we identified a total of 2375 protein groups from the retinal protein samples of RCS rats and non-dystrophic congenic controls. Four hundred thirty-four significantly DEPs were selected by Student's t -test. Based on the results of the bioinformatics analysis, we identified mitochondrial dysfunction and transcription factor E2F1 as the key initiation factors in early retinal degenerative process. We showed that the mitochondrial dysfunction and the transcription factor E2F1 substantially contribute to the disease etiology of RP. The results provide a new potential therapeutic approach for this retinal degenerative disease.

  5. Proteomic profiling of early degenerative retina of RCS rats

    Directory of Open Access Journals (Sweden)

    Zhi-Hong Zhu

    2017-06-01

    Full Text Available AIM: To identify the underlying cellular and molecular changes in retinitis pigmentosa (RP. METHODS: Label-free quantification-based proteomics analysis, with its advantages of being more economic and consisting of simpler procedures, has been used with increasing frequency in modern biological research. Dystrophic RCS rats, the first laboratory animal model for the study of RP, possess a similar pathological course as human beings with the diseases. Thus, we employed a comparative proteomics analysis approach for in-depth proteome profiling of retinas from dystrophic RCS rats and non-dystrophic congenic controls through Linear Trap Quadrupole - orbitrap MS/MS, to identify the significant differentially expressed proteins (DEPs. Bioinformatics analyses, including Gene ontology (GO and Kyoto Encyclopedia of Genes and Genomes (KEGG pathway annotation and upstream regulatory analysis, were then performed on these retina proteins. Finally, a Western blotting experiment was carried out to verify the difference in the abundance of transcript factor E2F1. RESULTS: In this study, we identified a total of 2375 protein groups from the retinal protein samples of RCS rats and non-dystrophic congenic controls. Four hundred thirty-four significantly DEPs were selected by Student’s t-test. Based on the results of the bioinformatics analysis, we identified mitochondrial dysfunction and transcription factor E2F1 as the key initiation factors in early retinal degenerative process. CONCLUSION: We showed that the mitochondrial dysfunction and the transcription factor E2F1 substantially contribute to the disease etiology of RP. The results provide a new potential therapeutic approach for this retinal degenerative disease.

  6. Systemic administration of erythropoietin inhibits retinopathy in RCS rats.

    Directory of Open Access Journals (Sweden)

    Weiyong Shen

    Full Text Available OBJECTIVE: Royal College of Surgeons (RCS rats develop vasculopathy as photoreceptors degenerate. The aim of this study was to examine the effect of erythropoietin (EPO on retinopathy in RCS rats. METHODS: Fluorescein angiography was used to monitor retinal vascular changes over time. Changes in retinal glia and vasculature were studied by immunostaining. To study the effects of EPO on retinal pathology, EPO (5000 IU/kg was injected intraperitoneally in 14 week old normal and RCS rats twice a week for 4 weeks. Changes in the retinal vasculature, glia and microglia, photoreceptor apoptosis, differential expression of p75 neurotrophin receptor (p75NTR, pro-neurotrophin 3 (pro-NT3, tumour necrosis factor-α (TNFα, pigment epithelium derived factor (PEDF and vascular endothelial growth factor-A (VEGF-A, the production of CD34(+ cells and mobilization of CD34(+/VEGF-R2(+ cells as well as recruitment of CD34(+ cells into the retina were examined after EPO treatment. RESULTS: RCS rats developed progressive capillary dropout and subretinal neovascularization which were accompanied by retinal gliosis. Systemic administration of EPO stabilized the retinal vasculature and inhibited the development of focal vascular lesions. Further studies showed that EPO modulated retinal gliosis, attenuated photoreceptor apoptosis and p75NTR and pro-NT3 upregulation, promoted the infiltration of ramified microglia and stimulated VEGF-A expression but had little effect on TNFα and PEDF expression. EPO stimulated the production of red and white blood cells and CD34(+ cells along with effective mobilization of CD34(+/VEGF-R2(+ cells. Immunofluorescence study demonstrated that EPO enhanced the recruitment of CD34+ cells into the retina. CONCLUSIONS: Our results suggest that EPO has therapeutic potentials in treatment of neuronal and vascular pathology in retinal disease. The protective effects of EPO on photoreceptors and the retinal vasculature may involve multiple

  7. Calculation of beam neutralization in the IPNS-Upgrade RCS

    International Nuclear Information System (INIS)

    Chae, Yong-Chul.

    1995-01-01

    The author calculated the neutralization of circulating beam in this report. In the calculation it is assumed that all electrons liberated from the background molecules due to the collisional processes are trapped in the potential well of the proton beam. Including the dependence of ionization cross sections on the kinetic energy of the incident particle, the author derived the empirical formula for beam neutralization as a function of time and baseline vacuum pressure, which is applicable to the one acceleration cycle of the IPNS-Upgrade RCS

  8. Anti-AMPA-Receptor Encephalitis Presenting as a Rapid-Cycling Bipolar Disorder in a Young Woman with Turner Syndrome

    Directory of Open Access Journals (Sweden)

    Giuseppe Quaranta

    2015-01-01

    Full Text Available Background. Autoimmune encephalitis is a disorder characterised by the subacute onset of seizures, short-term memory loss, and psychiatric and behavioural symptoms. Initially, it was recognised as a paraneoplastic disorder, but recently a subgroup of patients without systemic cancer was identified. Case Description. We describe a 20-year-old woman with Turner syndrome presenting with a treatment-resistant rapid cycling bipolar disorder with cognitive impairment. She was diagnosed with anti-AMPA-receptor encephalitis. She showed marked improvement after starting memantine and valproic acid. Conclusion. This case description emphasises the importance of timely recognition of autoimmune limbic encephalitis in patients with psychiatric manifestations and a possible predisposition to autoimmune conditions, in order to rule out malignancy and to quickly initiate treatment.

  9. Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB.

    Science.gov (United States)

    Filippova, Ekaterina V; Zemaitaitis, Bozena; Aung, Theint; Wolfe, Alan J; Anderson, Wayne F

    2018-02-27

    RcsB is a highly conserved transcription regulator of the Rcs phosphorelay system, a complex two-component signal transduction system (N. Majdalani and S. Gottesman, Annu Rev Microbiol 59:379-405, 2005; A. J. Wolfe, Curr Opin Microbiol 13:204-209, 2010, https://doi.org/10.1016/j.mib.2010.01.002; D. J. Clarke, Future Microbiol 5:1173-1184, 2010, https://doi.org/10.2217/fmb.10.83). RcsB plays an important role in virulence and pathogenicity in human hosts by regulating biofilm formation. RcsB can regulate transcription alone or together with its auxiliary transcription regulators by forming heterodimers. This complexity allows RcsB to regulate transcription of more than 600 bacterial genes in response to different stresses (D. Wang et al., Mol Plant Microbe Interact 25:6-17, 2012, https://doi.org/10.1094/MPMI-08-11-0207). Despite increasing knowledge of RcsB importance, molecular mechanisms that drive the ability of RcsB to control transcription of a large number of genes remain unclear. Here, we present crystal structures of unphosphorylated RcsB in complex with the consensus DNA-binding sequence of 22-mer (DNA22) and 18-mer (DNA18) of the flhDC operon from Escherichia coli determined at 3.15- and 3.37-Å resolution, respectively. The results of our structural analysis combined with the results of in vitro binding assays provide valuable insights to the protein regulatory mechanism, demonstrate how RcsB recognizes target DNA sequences, and reveal a unique oligomeric state that allows RcsB to form homo- and heterodimers. This information will help us understand the complex mechanisms of transcriptional regulation by RcsB in bacteria. IMPORTANCE RcsB is a well-studied two-component response regulator of the Rcs phosphorelay system, conserved within the family Enterobacteriaceae , which includes many pathogens. It is a global regulator, controlling more than 5% of bacterial genes associated with capsule biosynthesis, flagellar biogenesis, cell wall biosynthesis

  10. Status and schedule of J-PARC 50 GeV synchrotron

    International Nuclear Information System (INIS)

    Oogoe, Takao; Yoshioka, Masakazu; Kobayashi, Hitoshi; Takeuchi, Yasunori; Shirakata, Masashi; Shirakabe, Yoshihisa; Kuniyasu, Yuu; Oki, Hiroshi; Takiyama, Youichi

    2005-01-01

    Japan Proton Accelerator Research Complex (J-PARC) is the research complex based on three high intensity proton Accelerators: a linac, a 3 GeV synchrotron (RCS), and a 50 GeV synchrotron (MR). The construction of the MR started in 2002, and its beam commissioning is scheduled in January of 2008. The accelerator tunnel of the J-PARC 50 GeV Synchrotron is still under construction, and will be completed at the end of 2006. Installation of accelerator-components is scheduled to start in July 2005 in parallel with civil and utility construction. This document describes how to install accelerator components in the tunnel and civil engineering of the tunnel. (author)

  11. Chemistry with synchrotron radiation

    International Nuclear Information System (INIS)

    Preses, J.; Grover, J.R.; White, M.G.; Kvick, A.

    1990-01-01

    An accidental by-product of high-energy physics, synchrotron radiation, has emerged as one of the most powerful tools for the understanding of chemical reactions. Advances made by using synchrotron radiation in physical chemistry are reviewed herein. Descriptions of experiments exploiting the many ways that synchrotron radiation can be manipulated are presented. These manipulations include intensification of the radiation and compression or shifting of its spectral structure. Combinations of the use of synchrotron radiation, which provides access to very short wavelengths and is, at the same time, continuously and easily tunable, with laser radiation, which offers much higher resolution and much more intense radiation per pulse, but is difficult to tune in the ultraviolet region of the spectra, gives the chemist a way to map a molecule's potential energy curve, to note the lengths and strengths of chemical bonds, and to predict and explain novel reactions of more complex molecules. The use of diffraction of x-rays to study the spacing of atoms in crystals is discussed. Various applications of synchrotron radiation to studies of the fluorescence of hydrocarbons and to the chiral dichroism studies of other natural products like DNA and RNA are described. Methods for enhancing synchrotron light sources by insertion devices, such as wigglers and undulators, that increase the available photo flux and construction of new sources of synchrotron radiation are mentioned

  12. RCS Leak Rate Calculation with High Order Least Squares Method

    International Nuclear Information System (INIS)

    Lee, Jeong Hun; Kang, Young Kyu; Kim, Yang Ki

    2010-01-01

    As a part of action items for Application of Leak before Break(LBB), RCS Leak Rate Calculation Program is upgraded in Kori unit 3 and 4. For real time monitoring of operators, periodic calculation is needed and corresponding noise reduction scheme is used. This kind of study was issued in Korea, so there have upgraded and used real time RCS Leak Rate Calculation Program in UCN unit 3 and 4 and YGN unit 1 and 2. For reduction of the noise in signals, Linear Regression Method was used in those programs. Linear Regression Method is powerful method for noise reduction. But the system is not static with some alternative flow paths and this makes mixed trend patterns of input signal values. In this condition, the trend of signal and average of Linear Regression are not entirely same pattern. In this study, high order Least squares Method is used to follow the trend of signal and the order of calculation is rearranged. The result of calculation makes reasonable trend and the procedure is physically consistence

  13. Numerical simulation of RCS for carrier electronic warfare airplanes

    Directory of Open Access Journals (Sweden)

    Yue Kuizhi

    2015-04-01

    Full Text Available This paper studies the radar cross section (RCS of carrier electronic warfare airplanes. Under the typical naval operations section, the mathematical model of the radar wave’s pitch angle incidence range analysis is established. Based on the CATIA software, considering dynamic deflections of duck wing leading edge flaps, flaperons, horizontal tail, and rudder, as well as aircraft with air-to-air missile, anti-radiation missile, electronic jamming pod, and other weapons, the 3D models of carrier electronic warfare airplanes Model A and Model B with weapons were established. Based on the physical optics method and the equivalent electromagnetic flow method, by the use of the RCSAnsys software, the characteristics of carrier electronic warfare airplanes’ RCS under steady and dynamic flights were simulated under the UHF, X, and S radar bands. This paper researches the detection probability of aircraft by radars under the condition of electronic warfare, and completes the mathematical statistical analysis of the simulation results. The results show that: The Model A of carrier electronic warfare airplane is better than Model B on stealth performance and on discover probability by radar detection effectively.

  14. Dynamic radar cross section measurements of a full-scale aircraft for RCS modelling validation

    CSIR Research Space (South Africa)

    Van Schalkwyk, Richard F

    2017-10-01

    Full Text Available In this paper the process followed in generating a high fidelity reference data set for radar cross section (RCS) modelling validation for a full-scale aircraft, is presented. An overview of two dynamic RCS measurement campaigns, involving both...

  15. The Rcs regulon in Proteus mirabilis: implications for motility, biofilm formation, and virulence.

    Science.gov (United States)

    Howery, Kristen E; Clemmer, Katy M; Rather, Philip N

    2016-11-01

    The overall role of the Rcs phosphorelay in Proteus mirabilis is largely unknown. Previous work had demonstrated that the Rcs phosphorelay represses the flhDC operon and activates the minCDE cell division inhibition system. To identify additional cellular functions regulated by the Rcs phosphorelay, an analysis of RNA-seq data was undertaken. In this report, the results of the RNA-sequencing are discussed with an emphasis on the predicted roles of the Rcs phosphorelay in swarmer cell differentiation, motility, biofilm formation, and virulence. RcsB is shown to activate genes important for differentiation and fimbriae formation, while repressing the expression of genes important for motility and virulence. Additionally, to follow up on the RNA-Seq data, we demonstrate that an rcsB mutant is deficient in its ability to form biofilm and exhibits enhanced virulence in a Galleria mellonella waxworm model. Overall, these results indicate the Rcs regulon in P. mirabilis extends beyond flagellar genes to include those involved in biofilm formation and virulence. Furthermore, the information presented in this study may provide clues to additional roles of the Rcs phosphorelay in other members of the Enterobacteriaceae.

  16. Synchrotron radiation at Trieste

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1986-06-15

    The fast developing field of synchrotron radiation has its origins in the mastery of storage rings in high energy physics and is a prime example of spinoff from pure science. Intense electromagnetic radiation streams off when beams of high energy electrons are bent or shaken. This synchrotron radiation was once an annoying waste of energy in particle storage rings, but now the wheel has turned full circle, with dedicated machines supplying this radiation for a wide range of science. The astonishing growth rate in this field was highlighted at an International Conference on Synchrotron Radiation, held at the International Centre for Theoretical Physics (ICTP), Trieste, Italy from 7-11 April.

  17. National Synchrotron Light Source

    International Nuclear Information System (INIS)

    van Steenbergen, A.

    1979-01-01

    The National Synchrotron Light Source comprises two high intensity electron storage rings for the generation of intense fluxes of synchrotron radiation in the vuv wavelength domain (700 MeV e - ring) and in the x-ray wavelength domain (2.5 GeV e - ring). A description is presented of the basic facility and the characteristics of the synchrotron radiation sources. The present plans for specific beam lines will be enumerated and the planned use of beam wigglers and undulators will be discussed

  18. Synchrotron radiation at Trieste

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    The fast developing field of synchrotron radiation has its origins in the mastery of storage rings in high energy physics and is a prime example of spinoff from pure science. Intense electromagnetic radiation streams off when beams of high energy electrons are bent or shaken. This synchrotron radiation was once an annoying waste of energy in particle storage rings, but now the wheel has turned full circle, with dedicated machines supplying this radiation for a wide range of science. The astonishing growth rate in this field was highlighted at an International Conference on Synchrotron Radiation, held at the International Centre for Theoretical Physics (ICTP), Trieste, Italy from 7-11 April

  19. National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Hulbert, S.L.; Lazarz, N.M.

    1991-04-01

    This report discussion research being conducted at the National Synchrotron light source. In particular, this report contains operations summaries; symposia, workshops, and projects; NSLS highlights; and abstracts of science at the NSLS

  20. Uses of synchrotron radiation

    International Nuclear Information System (INIS)

    Gordon, B.M.

    1982-01-01

    X-ray fluorescence has long been used as a technique for elemental analysis. X-ray fluorescence techniques have a number of features that make them attractive for application to biomedical samples. In the past few years synchrotron radiation x-ray sources have been developed and, because of their properties, their use can improve the sensitivity for trace element analysis by two to three orders of magnitude. Also, synchrotron radiation will make possible an x-ray microprobe with resolution in the micrometer range. The National Synchrotron Light Source (NSLS), a dedicated synchrotron radiation source recently built at Brookhaven National Laboratory, will have a facility for trace element analysis by x-ray fluorescence and will be available to all interested users

  1. The Australian synchrotron

    International Nuclear Information System (INIS)

    Farhi, R.

    2005-06-01

    This document recalls the historical aspects of the Australian Synchrotron which will be implemented in 2007. It presents then the objectives of this program, the specifications of the ring and the light lines. (A.L.B.)

  2. Inauguration of Proton Synchrotron

    CERN Multimedia

    1960-01-01

    On 5 February 1960, the Proton Synchrotron (PS) was formally inaugurated. The great Danish physicist, Niels Bohr, releases a bottle of champagne against a shielding block to launch the PS on its voyage in physics.

  3. A Disulfide Bond in the Membrane Protein IgaA Is Essential for Repression of the RcsCDB System

    Directory of Open Access Journals (Sweden)

    M. Graciela Pucciarelli

    2017-12-01

    Full Text Available IgaA is an integral inner membrane protein that was discovered as repressor of the RcsCDB phosphorelay system in the intracellular pathogen Salmonella enterica serovar Typhimurium. The RcsCDB system, conserved in many members of the family Enterobacteriaceae, regulates expression of varied processes including motility, biofilm formation, virulence and response to envelope stress. IgaA is an essential protein to which, in response to envelope perturbation, the outer membrane lipoprotein RcsF has been proposed to bind in order to activate the RcsCDB phosphorelay. Envelope stress has also been reported to be sensed by a surface exposed domain of RcsF. These observations support a tight control of the RcsCDB system by RcsF and IgaA via mechanisms that, however, remain unknown. Interestingly, RcsF and IgaA have four conserved cysteine residues in loops exposed to the periplasmic space. Two non-consecutive disulfide bonds were shown to be required for RcsF function. Here, we report mutagenesis studies supporting the presence of one disulfide bond (C404-C425 in the major periplasmic loop of IgaA that is essential for repression of the RcsCDB phosphorelay. Our data therefore suggest that the redox state of the periplasm may be critical for the control of the RcsCDB system by its two upstream regulators, RcsF and IgaA.

  4. European Synchrotron Radiation Facility

    International Nuclear Information System (INIS)

    Buras, B.

    1985-01-01

    How a European Synchrotron Radiation Facility has developed into a detailed proposal recently accepted as the basis for construction of the facility at Grenoble is discussed. In November 1977, the General Assembly of the European Science Foundation (ESF) approved the report of the ESF working party on synchrotron radiation entitled Synchrotron Radiation - a Perspective View for Europe. This report contained as one of its principal recommendations that work should commence on a feasibility study for a European synchrotron radiation laboratory having a dedicated hard X-ray storage ring and appropriate advanced instrumentation. In order to prepare a feasibility study the European Science Foundation set up the Ad-hoc Committee on Synchrotron Radiation, which in turn formed two working groups: one for the machine and another for instrumentation. This feasibility study was completed in 1979 with the publication of the Blue Book describing in detail the so called 1979 European Synchrotron Radiation Facility. The heart of the facility was a 5 GeV electron storage ring and it was assumed that mainly the radiation from bending magnets will be used. The facility is described

  5. Reduced mRNA expression of PTGDS in peripheral blood mononuclear cells of rapid-cycling bipolar disorder patients compared with healthy control subjects

    DEFF Research Database (Denmark)

    Munkholm, Klaus; Peijs, Lone; Kessing, Lars Vedel

    2015-01-01

    was measured in 37 rapid-cycling bipolar disorder patients and 40 age- and gender-matched healthy control subjects using reverse transcription quantitative real-time polymerase chain reaction. Repeated measurements of PTGDS and AKR1C3 mRNA expression were obtained in various affective states during 6-12 months...... and compared with repeated measurements in healthy control subjects. RESULTS: Adjusted for age and gender, PTGDS mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects. No difference in PTGDS m...

  6. A Hybrid Optimization Algorithm for Low RCS Antenna Design

    Directory of Open Access Journals (Sweden)

    W. Shao

    2012-12-01

    Full Text Available In this article, a simple and efficient method is presented to design low radar cross section (RCS patch antennas. This method consists of a hybrid optimization algorithm, which combines a genetic algorithm (GA with tabu search algorithm (TSA, and electromagnetic field solver. The TSA, embedded into the GA frame, defines the acceptable neighborhood region of parameters and screens out the poor-scoring individuals. Thus, the repeats of search are avoided and the amount of time-consuming electromagnetic simulations is largely reduced. Moreover, the whole design procedure is auto-controlled by programming the VBScript language. A slot patch antenna example is provided to verify the accuracy and efficiency of the proposed method.

  7. Improvement on RCS reduction using flat lossy focusing reflectors.

    Science.gov (United States)

    Chin, Cheng-Yuan; Jou, Christina F

    2013-12-30

    In this paper, we propose a planar non-periodic subwavelength resistive grating (SWRG). The phase front of the scattered fields can be completely manipulated through non-periodic design of the grating while high absorptivity is preserved. The SWRG has an interesting property similar to a resistive concave reflecting lens. Scattered wave is focused in the near-field region, and spread out in the far-field. This feature of non-periodic resistive grating can improve the original radar cross section (RCS) reduction up to 22.86 dB in the boresight direction comparing to the periodic counterpart. Non-periodic design of SWRG could have a substantial impact on stealth technology, aerospace engineering, and microwave anechoic chamber.

  8. Analysis of specific factors causing RCS pressure boundary cracking

    International Nuclear Information System (INIS)

    Song, Taek-Ho; Jeong, Il-Seok

    2007-01-01

    As nuclear power plants become aged, pressure boundary integrity has become so important issue in domestic and foreign nuclear industry that many related research projects are on-going. KEPRI is going to embark a new research project for managing and preventing these kinds of cracks in nuclear power plants (NPPs). Many nuclear power plants experienced pressure boundary stress corrosion cracking (SCC) and shut downed because of it. In USA, V.C. Summer plant experienced reactor coolant pipe SCC near reactor outlet nozzle and Davis Vesse plant experienced reactor head crack around penetration pipe which is used to control rod drive mechanism. In this paper, RCS pressure boundary cracking cases and corrosion potential have been studied to find out what are the specific factors that have affected crack initiations in the reactor coolant pressure boundaries

  9. Genetic analysis of morphological traits in a new, versatile, rapid-cycling Brassica rapa recombinant inbred line population

    Directory of Open Access Journals (Sweden)

    Hedayat eBagheri

    2012-08-01

    Full Text Available A recombinant inbred line (RIL population was produced based on a wide cross between the rapid-cycling and self-compatible genotypes L58, a Caixin vegetable type, and R-o-18, a yellow sarson oil type. A linkage map based on 160 F7 lines was constructed using 100 SNP, 130 AFLP®, 27 InDel and 13 publicly available SSR markers. The map covers a total length of 1150 cM with an average resolution of 4.3 cM/marker. To demonstrate the versatility of this new population, 17 traits, related to plant architecture and seed characteristics, were subjected to QTL analysis. A total of 47 QTLs were detected, each explaining between 6 to 54% of the total phenotypic variance for the concerned trait. The genetic analysis shows that this population is a useful new tool for analyzing genetic variation for interesting traits in B. rapa, and for further exploitation of the recent availability of the B. rapa whole genome sequence for gene cloning and gene function analysis.

  10. DNA-based genetic markers for Rapid Cycling Brassica rapa (Fast Plants type designed for the teaching laboratory.

    Directory of Open Access Journals (Sweden)

    Eryn E. Slankster

    2012-06-01

    Full Text Available We have developed DNA-based genetic markers for rapid-cycling Brassica rapa (RCBr, also known as Fast Plants. Although markers for Brassica rapa already exist, ours were intentionally designed for use in a teaching laboratory environment. The qualities we selected for were robust amplification in PCR, polymorphism in RCBr strains, and alleles that can be easily resolved in simple agarose slab gels. We have developed two single nucleotide polymorphism (SNP based markers and 14 variable number tandem repeat (VNTR-type markers spread over four chromosomes. The DNA sequences of these markers represent variation in a wide range of genomic features. Among the VNTR-type markers, there are examples of variation in a nongenic region, variation within an intron, and variation in the coding sequence of a gene. Among the SNP-based markers there are examples of polymorphism in intronic DNA and synonymous substitution in a coding sequence. Thus these markers can serve laboratory exercises in both transmission genetics and molecular biology.

  11. Future Synchrotron Radiation Sources

    CERN Document Server

    Winick, Herman

    2003-01-01

    Sources of synchrotron radiation (also called synchrotron light) and their associated research facilities have experienced a spectacular growth in number, performance, and breadth of application in the past two to three decades. In 1978 there were eleven electron storage rings used as light sources. Three of these were small rings, all below 500 mega-electron volts (MeV), dedicated to this purpose; the others, with energy up to 5 giga-electron volts (GeV), were used parasitically during the operation of the ring for high energy physics research. In addition, at that time synchrotron radiation from nine cyclic electron synchrotrons, with energy up to 5 GeV, was also used parasitically. At present no cyclic synchrotrons are used, while about 50 electron storage rings are in operation around the world as fully dedicated light sources for basic and applied research in a wide variety of fields. Among these fields are structural molecular biology, molecular environmental science, materials, analytic chemistry, micr...

  12. Australian synchrotron radiation science

    International Nuclear Information System (INIS)

    White, J.W.

    1996-01-01

    Full text: The Australian Synchrotron Radiation Program, ASRP, has been set up as a major national research facility to provide facilities for scientists and technologists in physics, chemistry, biology and materials science who need access to synchrotron radiation. Australia has a strong tradition in crystallography and structure determination covering small molecule crystallography, biological and protein crystallography, diffraction science and materials science and several strong groups are working in x-ray optics, soft x-ray and vacuum ultra-violet physics. A number of groups whose primary interest is in the structure and dynamics of surfaces, catalysts, polymer and surfactant science and colloid science are hoping to use scattering methods and, if experience in Europe, Japan and USA can be taken as a guide, many of these groups will need third generation synchrotron access. To provide for this growing community, the Australian National Beamline at the Photon Factory, Tsukuba, Japan, has been established since 1990 through a generous collaboration with Japanese colleagues, the beamline equipment being largely produced in Australia. This will be supplemented in 1997 with access to the world's most powerful synchrotron x-ray source at the Advanced Photon Source, Argonne National Laboratory, USA. Some recent experiments in surface science using neutrons as well as x-rays from the Australian National Beamline will be used to illustrate one of the challenges that synchrotron x-rays may meet

  13. On the radar cross section (RCS) prediction of vehicles moving on the ground

    International Nuclear Information System (INIS)

    Sabihi, Ahmad

    2014-01-01

    As readers should be aware, Radar Cross Section depends on the factors such as: Wave frequency and polarization, Target dimension, angle of ray incidence, Target’s material and covering, Type of radar system as monostatic or bistatic, space in which contains target and propagating waves, and etc. Having moved or stationed in vehicles can be effective in RCS values. Here, we investigate effective factors in RCS of moving targets on the ground or sea. Image theory in electromagnetic applies to be taken into account RCS of a target over the ground or sea

  14. On the radar cross section (RCS) prediction of vehicles moving on the ground

    Energy Technology Data Exchange (ETDEWEB)

    Sabihi, Ahmad [Department of Mathematical Sciences, Sharif University of Technology, Tehran (Iran, Islamic Republic of)

    2014-12-10

    As readers should be aware, Radar Cross Section depends on the factors such as: Wave frequency and polarization, Target dimension, angle of ray incidence, Target’s material and covering, Type of radar system as monostatic or bistatic, space in which contains target and propagating waves, and etc. Having moved or stationed in vehicles can be effective in RCS values. Here, we investigate effective factors in RCS of moving targets on the ground or sea. Image theory in electromagnetic applies to be taken into account RCS of a target over the ground or sea.

  15. Precision synchrotron radiation detectors

    International Nuclear Information System (INIS)

    Levi, M.; Rouse, F.; Butler, J.

    1989-03-01

    Precision detectors to measure synchrotron radiation beam positions have been designed and installed as part of beam energy spectrometers at the Stanford Linear Collider (SLC). The distance between pairs of synchrotron radiation beams is measured absolutely to better than 28 /mu/m on a pulse-to-pulse basis. This contributes less than 5 MeV to the error in the measurement of SLC beam energies (approximately 50 GeV). A system of high-resolution video cameras viewing precisely-aligned fiducial wire arrays overlaying phosphorescent screens has achieved this accuracy. Also, detectors of synchrotron radiation using the charge developed by the ejection of Compton-recoil electrons from an array of fine wires are being developed. 4 refs., 5 figs., 1 tab

  16. Properties of synchrotron radiation

    International Nuclear Information System (INIS)

    Materlik, G.

    1982-01-01

    This paper forms the introductory chapter to a book concerning the use of synchrotron radiation for investigation of the structure and mechanism of biological macromolecules. After a historical section, the physics of synchrotron radiation is summarized so that the most promising experiments may be extrapolated. Irradiated power and intensity, polarization and angular distribution, brilliance of a real source, and developments such as wigglers and undulators are briefly dealt with. The paper includes a tabulated compilation of proposed and operating machines in 1982, with some of their characteristics. (U.K.)

  17. RCS estimation of linear and planar dipole phased arrays approximate model

    CERN Document Server

    Singh, Hema; Jha, Rakesh Mohan

    2016-01-01

    In this book, the RCS of a parallel-fed linear and planar dipole array is derived using an approximate method. The signal propagation within the phased array system determines the radar cross section (RCS) of phased array. The reflection and transmission coefficients for a signal at different levels of the phased-in scattering array system depend on the impedance mismatch and the design parameters. Moreover the mutual coupling effect in between the antenna elements is an important factor. A phased array system comprises of radiating elements followed by phase shifters, couplers, and terminating load impedance. These components lead to respective impedances towards the incoming signal that travels through them before reaching receive port of the array system. In this book, the RCS is approximated in terms of array factor, neglecting the phase terms. The mutual coupling effect is taken into account. The dependence of the RCS pattern on the design parameters is analyzed. The approximate model is established as a...

  18. Mutual Coupling Effects for Radar Cross Section (RCS of a Series-Fed Dipole Antenna Array

    Directory of Open Access Journals (Sweden)

    H. L. Sneha

    2012-01-01

    Full Text Available The estimation of RCS of a phased array depends on various parameters, namely, array geometry, operational frequency, feed network, mutual coupling between the antenna elements and so fourth. This paper presents the estimation of RCS of linear dipole array with series-feed network by tracing the signal path from the antenna aperture into the feed network. The effect of mutual coupling exhibited by the dipole antenna is considered for three configurations namely, side by side, collinear, and parallel in echelon. It is shown that the mutual coupling affects the antenna pattern (and hence RCS significantly for larger scan angles. Further it is inferred that the RCS of phased array can be optimized by (i reducing the length of the dipole, (ii termination of the isolation port of the coupler with a suitable load, and (iii using suitable amplitude distribution.

  19. Detailed evaluation of RCS boundary rupture during high-pressure severe accident sequences

    International Nuclear Information System (INIS)

    Park, Rae-Joon; Hong, Seong-Wan

    2011-01-01

    A depressurization possibility of the reactor coolant system (RCS) before a reactor vessel rupture during a high-pressure severe accident sequence has been evaluated for the consideration of direct containment heating (DCH) and containment bypass. A total loss of feed water (TLOFW) and a station blackout (SBO) of the advanced power reactor 1400 (APR 1400) has been evaluated from an initiating event to a creep rupture of the RCS boundary by using the SCDAP/RELAP5 computer code. In addition, intentional depressurization of the RCS using power-operated safety relief valves (POSRVs) has been evaluated. The SCDAPRELAP5 results have shown that the pressurizer surge line broke before the reactor vessel rupture failure, but a containment bypass did not occur because steam generator U tubes did not break. The intentional depressurization of the RCS using POSRV was effective for the DCH prevention at a reactor vessel rupture. (author)

  20. Research on the Scattering Characteristics and the RCS Reduction of Circularly Polarized Microstrip Antenna

    Directory of Open Access Journals (Sweden)

    W. Jiang

    2013-01-01

    Full Text Available Based on the study of the radiation and scattering of the circularly polarized (CP antenna, a novel radar cross-section (RCS reduction technique is proposed for CP antenna in this paper. Quasi-fractal slots are applied in the design of the antenna ground plane to reduce the RCS of the CP antenna. Both prototype antenna and array are designed, and their time-, frequency-, and space-domain characteristics are studied to authenticate the proposed technique. The simulated and measured results show that the RCS of the prototype antenna and array is reduced up to 7.85 dB and 6.95 dB in the band of 1 GHz–10 GHz. The proposed technique serves a candidate in the design of low RCS CP antennas and arrays.

  1. Radar cross-section (RCS) analysis of high frequency surface wave radar targets

    OpenAIRE

    ÇAKIR, Gonca; SEVGİ, Levent

    2010-01-01

    Realistic high frequency surface wave radar (HFSWR) targets are investigated numerically in terms of electromagnetic wave -- target interactions. Radar cross sections (RCS) of these targets are simulated via both the finite-difference time-domain (FDTD) method and the Method of Moments (MoM). The virtual RCS prediction tool that was introduced in previous work is used for these investigations. The virtual tool automatically creates the discrete FDTD model of the target under investi...

  2. Reflectometry with synchrotron radiation

    International Nuclear Information System (INIS)

    Krumrey, Michael; Cibik, Levent; Fischer, Andreas; Gottwald, Alexander; Kroth, Udo; Scholze, Frank

    2014-01-01

    The measurement of the reflectivity for VUV, XUV, and X-radiation at the PTB synchrotron radiation sources is described. The corresponding data of the used beams are presented. Results of experiments on a Cu-Ni double-layer, SiO 2 , Si, and MgF 2 are presented. (HSI)

  3. Coherent synchrotron radiation

    International Nuclear Information System (INIS)

    Agoh, Tomonori

    2006-01-01

    This article presents basic properties of coherent synchrotron radiation (CSR) with numerical examples and introduces the reader to important aspects of CSR in future accelerators with short bunches. We show interesting features of the single bunch instability due to CSR in storage rings and discuss the longitudinal CSR field via the impedance representation. (author)

  4. Characteristics of synchrotron radiation

    International Nuclear Information System (INIS)

    Brown, G.S.

    1984-01-01

    The characteristics and production of synchrotron radiation are qualitatively discussed. The spectral properties of wigglers and undulators are briefly described. Possible applications in condensed matter physics are outlined. These include atomic and molecular studies, crystallography, impurities in solids and radiographic imaging

  5. Synchrotron radiation research

    International Nuclear Information System (INIS)

    Markus, N.

    1995-01-01

    In the many varied application fields of accelerators, synchrotron radiation ranks as one of the most valuable and widely useful tools. Synchrotron radiation is produced in multi-GeV electron synchrotrons and storage rings, and emerges tangentially in a narrow vertical fan. Synchrotron radiation has been used extensively for basic studies and, more recently, for applied research in the chemical, materials, biotechnology and pharmaceutical industries. Initially, the radiation was a byproduct of high energy physics laboratories but the high demand soon resulted in the construction of dedicated electron storage rings. The accelerator technology is now well developed and a large number of sources have been constructed, with energies ranging from about 1.5 to 8 GeV including the 6 GeV European Synchrotron Radiation Facility (ESRF) source at Grenoble, France. A modern third-generation synchrotron radiation source has an electron storage ring with a complex magnet lattice to produce ultra-low emittance beams, long straights for 'insertion devices', and 'undulator' or 'wiggler' magnets to generate radiation with particular properties. Large beam currents are necessary to give high radiation fluxes and long beam lifetimes require ultra high vacuum systems. Industrial synchrotron radiation research programmes use either Xray diffraction or spectroscopy to determine the structures of a wide range of materials. Biological and pharmaceutical applications study the functions of various proteins. With this knowledge, it is possible to design molecules to change protein behaviour for pharmaceuticals, or to configure more active proteins, such as enzymes, for industrial processes. Recent advances in molecular biology have resulted in a large increase in protein crystallography studies, with researchers using crystals which, although small and weakly diffracting, benefit from the high intensity. Examples with commercial significance include the study of

  6. An efficient hybrid technique in RCS predictions of complex targets at high frequencies

    Science.gov (United States)

    Algar, María-Jesús; Lozano, Lorena; Moreno, Javier; González, Iván; Cátedra, Felipe

    2017-09-01

    Most computer codes in Radar Cross Section (RCS) prediction use Physical Optics (PO) and Physical theory of Diffraction (PTD) combined with Geometrical Optics (GO) and Geometrical Theory of Diffraction (GTD). The latter approaches are computationally cheaper and much more accurate for curved surfaces, but not applicable for the computation of the RCS of all surfaces of a complex object due to the presence of caustic problems in the analysis of concave surfaces or flat surfaces in the far field. The main contribution of this paper is the development of a hybrid method based on a new combination of two asymptotic techniques: GTD and PO, considering the advantages and avoiding the disadvantages of each of them. A very efficient and accurate method to analyze the RCS of complex structures at high frequencies is obtained with the new combination. The proposed new method has been validated comparing RCS results obtained for some simple cases using the proposed approach and RCS using the rigorous technique of Method of Moments (MoM). Some complex cases have been examined at high frequencies contrasting the results with PO. This study shows the accuracy and the efficiency of the hybrid method and its suitability for the computation of the RCS at really large and complex targets at high frequencies.

  7. Design and Development Comparison of Rapid Cycle Amine 1.0, 2.0, and 3.0

    Science.gov (United States)

    Chullen, Cinda; Campbell, Colin; Papale, William; Murray, Sean; Wichowski, Robert; Conger, Bruce; McMillin, Summer

    2016-01-01

    The development of the Rapid Cycle Amine (RCA) swing-bed technology for carbon dioxide (CO2) removal has been in progress since favorable results were published in 1996. Shortly thereafter, a prototype was designed, developed, and tested successfully and delivered to Johnson Space Center in 1999. An improved prototype (RCA 1.0) was delivered to NASA in 2006 and sized for the extravehicular activity (EVA). The RCA swing-bed technology is a regenerative system which employs two alternating solid-amine sorbent beds to remove CO2 and water. The two-bed design employs a chemisorption process whereby the beds alternate between adsorption and desorption. This process provides for an efficient RCA operation that enables one bed to be in adsorb (uptake) mode, while the other is in the desorb (regeneration) mode. The RCA has progressed through several iterations of technology readiness levels. Test articles have now been designed, developed, and tested for the advanced space suit portable life support system (PLSS) including RCA 1.0, RCA 2.0, and RCA 3.0. The RCA 3.0 was the most recent RCA fabrication and was delivered to NASA-JSC in June 2015. The RCA 1.0 test article was designed with a pneumatically actuated linear motion spool valve. The RCA 2.0 and 3.0 test articles were designed with a valve assembly which allows for switching between uptake and regeneration modes while minimizing gas volume losses to the vacuum source. RCA 2.0 and 3.0 also include an embedded controller design to control RCA operation and provide the capability of interfacing with various sensors and other ventilation loop components. The RCA technology is low power, small, and has fulfilled all test requirements levied upon the technology during development testing thus far. This paper will provide an overview of the design and development of RCA 1.0, 2.0 and 3.0 including detail differences between the design specifications of each. Nomenclature.

  8. Regulation of the Min Cell Division Inhibition Complex by the Rcs Phosphorelay in Proteus mirabilis.

    Science.gov (United States)

    Howery, Kristen E; Clemmer, Katy M; Şimşek, Emrah; Kim, Minsu; Rather, Philip N

    2015-08-01

    A key regulator of swarming in Proteus mirabilis is the Rcs phosphorelay, which represses flhDC, encoding the master flagellar regulator FlhD4C2. Mutants in rcsB, the response regulator in the Rcs phosphorelay, hyperswarm on solid agar and differentiate into swarmer cells in liquid, demonstrating that this system also influences the expression of genes central to differentiation. To gain a further understanding of RcsB-regulated genes involved in swarmer cell differentiation, transcriptome sequencing (RNA-Seq) was used to examine the RcsB regulon. Among the 133 genes identified, minC and minD, encoding cell division inhibitors, were identified as RcsB-activated genes. A third gene, minE, was shown to be part of an operon with minCD. To examine minCDE regulation, the min promoter was identified by 5' rapid amplification of cDNA ends (5'-RACE), and both transcriptional lacZ fusions and quantitative real-time reverse transcriptase (qRT) PCR were used to confirm that the minCDE operon was RcsB activated. Purified RcsB was capable of directly binding the minC promoter region. To determine the role of RcsB-mediated activation of minCDE in swarmer cell differentiation, a polar minC mutation was constructed. This mutant formed minicells during growth in liquid, produced shortened swarmer cells during differentiation, and exhibited decreased swarming motility. This work describes the regulation and role of the MinCDE cell division system in P. mirabilis swarming and swarmer cell elongation. Prior to this study, the mechanisms that inhibit cell division and allow swarmer cell elongation were unknown. In addition, this work outlines for the first time the RcsB regulon in P. mirabilis. Taken together, the data presented in this study begin to address how P. mirabilis elongates upon contact with a solid surface. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  9. CORNELL: Synchrotron 25

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    A recent celebration marked the twenty-fifth anniversary of the Cornell Electron Synchrotron. The major milestone in the commissioning of the synchrotron was on October 11, 1967 when Helen Edwards, Boyce McDaniel, and Maury Tigner achieved a 7 GeV beam, a worldrecord energy for electron synchrotrons at that time. Like so many advances in experimental physics, this occurred early in the morning - 3 a.m.! The transition from accelerator commissioning to high energy physics operation was extremely rapid; 7 GeV operation for data collection was routine just five weeks later. Throughout its life as a source of photon and electron beams for fixed target experiments, the synchrotron maintained energy leadership for circular electron machines. Originally designed for operation at 10 GeV, eventually it consistently provided beams for experiments at energies up to 11.6 GeV. It now operates at 5 GeV, serving as the injector for the CESR electron-positron storage ring. Robert Wilson was director of the laboratory during the design and most of the construction of the machine. He left near the end of the construction to become the first director of Fermilab and was replaced by Boyce McDaniel, who guided the laboratory from the completion of the synchrotron to the construction and early operation of CESR. Wilson recalled how the laboratory had originally proposed a 3 GeV turnkey machine to be built entirely by industry and would fit in the space previously occupied by earlier Cornell accelerators. However, members of the laboratory realized that 3 GeV would not open new physics frontiers, that the construction of the accelerator was much of the fun of doing high energy physics experiments, and that a more challenging project was needed. This led to the proposal for the 10 GeV synchrotron which was built in the ''Cornell Style'' with many of the components fabricated and nearly all of the assembly done at Cornell

  10. CORNELL: Synchrotron 25

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1993-03-15

    A recent celebration marked the twenty-fifth anniversary of the Cornell Electron Synchrotron. The major milestone in the commissioning of the synchrotron was on October 11, 1967 when Helen Edwards, Boyce McDaniel, and Maury Tigner achieved a 7 GeV beam, a worldrecord energy for electron synchrotrons at that time. Like so many advances in experimental physics, this occurred early in the morning - 3 a.m.! The transition from accelerator commissioning to high energy physics operation was extremely rapid; 7 GeV operation for data collection was routine just five weeks later. Throughout its life as a source of photon and electron beams for fixed target experiments, the synchrotron maintained energy leadership for circular electron machines. Originally designed for operation at 10 GeV, eventually it consistently provided beams for experiments at energies up to 11.6 GeV. It now operates at 5 GeV, serving as the injector for the CESR electron-positron storage ring. Robert Wilson was director of the laboratory during the design and most of the construction of the machine. He left near the end of the construction to become the first director of Fermilab and was replaced by Boyce McDaniel, who guided the laboratory from the completion of the synchrotron to the construction and early operation of CESR. Wilson recalled how the laboratory had originally proposed a 3 GeV turnkey machine to be built entirely by industry and would fit in the space previously occupied by earlier Cornell accelerators. However, members of the laboratory realized that 3 GeV would not open new physics frontiers, that the construction of the accelerator was much of the fun of doing high energy physics experiments, and that a more challenging project was needed. This led to the proposal for the 10 GeV synchrotron which was built in the ''Cornell Style'' with many of the components fabricated and nearly all of the assembly done at Cornell.

  11. Expression of nitric oxide synthase during the development of RCS rat retinas.

    Science.gov (United States)

    Sharma, R K; Warfvinge, K; Ehinger, B

    2001-01-01

    Nitric oxide (NO) has been reported to be both neurodestructive and neuroprotective in the central nervous system and could possibly play an important role in neurodegenerative disorders. On the assumption that NO synthesis may influence degenerative processes in the retina, we have examined the development and distribution of nitric-oxide-synthase(NOS)-immunoreactive cells in developing Royal College of Surgeons (RCS) rat retinas, which is an animal model for retinal degeneration. An antibody against constitutive neuronal NOS was used for immunocytochemistry on RCS rat retinas from postnatal (PN) days 3, 7, 10, 14, 35, 70 and 281 and compared with that in the normal rats of PN days 3, 7, 10, 14, 54 and adults. Immunoreactive cells were not seen in PN 3 retinas but were distinctly seen in the PN 7 retina along with a plexus in the inner plexiform layer. In both groups (normal and RCS rats) a distinct sublayering of the plexus in the inner plexiform layer could be seen at PN 10, which became more distinct at PN 14. The immunoreactive cells were detected also in the oldest retina examined, which was PN 281 in the case of RCS rats. In both groups, certain amacrine cells, certain bipolar cells and certain horizontal cells were found to be immunoreactive. In conclusion, the developmental timetable of the NOS immunoreactivity was identical in the normal and the RCS rat retinas. The NOS-immunoreactive cells persisted in the RCS retinas even when the retina had degenerated extensively. Abnormalities with the inducible isoforms of NOS cannot be ruled out from this study. We conclude that the chronological and qualitative development of the constitutive neuronal NOS immunoreactivity is normal in RCS rat retinas. Copyright 2001 S. Karger AG, Basel

  12. Evaluation of High-Pressure RCS Natural Circulations Under Severe Accident Conditions

    International Nuclear Information System (INIS)

    Lee, Byung Chul; Bang, Young Suk; Suh, Nam Duk

    2006-01-01

    Since TMI-2 accident, the occurrence of severe accident natural circulations inside RCS during entire in-vessel core melt progressions before the reactor vessel breach had been emphasized and tried to clarify its thermal-hydraulic characteristics. As one of consolidated outcomes of these efforts, sophisticated models have been presented to explain the effects of a variety of engineering and phenomenological factors involved during severe accident mitigation on the integrity of RCS pressure boundaries, i.e. reactor pressure vessel(RPV), RCS coolant pipe and steam generator tubes. In general, natural circulation occurs due to density differences, which for single phase flow, is typically generated by temperature differences. Three natural circulation flows can be formed during severe accidents: in-vessel, hot leg countercurrent flow and flow through the coolant loops. Each of these flows may be present during high-pressure transients such as station blackout (SBO) and total loss of feedwater (TLOFW). As a part of research works in order to contribute on the completeness of severe accident management guidance (SAMG) in domestic plants by quantitatively assessing the RCS natural circulations on its integrity, this study presents basic approach for this work and some preliminary results of these efforts with development of appropriately detailed RCS model using MELCOR computer code

  13. Metasurface base on uneven layered fractal elements for ultra-wideband RCS reduction

    Science.gov (United States)

    Su, Jianxun; Cui, Yueyang; Li, Zengrui; Yang, Yaoqing Lamar; Che, Yongxing; Yin, Hongcheng

    2018-03-01

    A novel metasurface based on uneven layered fractal elements is designed and fabricated for ultra-wideband radar cross section (RCS) reduction in this paper. The proposed metasurface consists of two fractal subwavelength elements with different layer thickness. The reflection phase difference of 180° (±37°) between two unit cells covers an ultra-wide frequency range. Ultra-wideband RCS reduction results from the phase cancellation between two local waves produced by these two unit cells. The diffuse scattering of electromagnetic (EM) waves is caused by the randomized phase distribution, leading to a low monostatic and bistatic RCS simultaneously. This metasurface can achieve -10dB RCS reduction in an ultra-wide frequency range from 6.6 to 23.9 GHz with a ratio bandwidth (fH/fL) of 3.62:1 under normal incidences for both x- and y-polarized waves. Both the simulation and the measurement results are consistent to verify this excellent RCS reduction performance of the proposed metasurface.

  14. Wideband RCS Reduction of Microstrip Array Antenna Based on Absorptive Frequency Selective Surface and Microstrip Resonators

    Directory of Open Access Journals (Sweden)

    Jingjing Xue

    2017-01-01

    Full Text Available An approach for wideband radar cross section (RCS reduction of a microstrip array antenna is presented and discussed. The scheme is based on the microstrip resonators and absorptive frequency selective surface (AFSS with a wideband absorptive property over the low band 1.9–7.5 GHz and a transmission characteristic at high frequency 11.05 GHz. The AFSS is designed to realize the out-of-band RCS reduction and preserve the radiation performance simultaneously, and it is placed above the antenna with the operating frequency of 11.05 GHz. Moreover, the microstrip resonators are loaded to obtain the in-band RCS reduction. As a result, a significant RCS reduction from 1.5 GHz to 13 GHz for both types of polarization has been accomplished. Compared with the reference antenna, the simulated results exhibit that the monostatic RCS of the proposed array antenna in x- and y-polarization can be reduced as much as 17.6 dB and 21.5 dB, respectively. And the measured results agree well with the simulated ones.

  15. Subretinally transplanted embryonic stem cells rescue photoreceptor cells from degeneration in the RCS rats.

    Science.gov (United States)

    Schraermeyer, U; Thumann, G; Luther, T; Kociok, N; Armhold, S; Kruttwig, K; Andressen, C; Addicks, K; Bartz-Schmidt, K U

    2001-01-01

    The Royal College of Surgeons (RCS) rat is an animal model for retinal degeneration such as the age-related macular degeneration. The RCS rat undergoes a progressive retinal degeneration during the early postnatal period. A potential treatment to prevent this retinal degeneration is the transplantation into the subretinal space of cells that would replace functions of the degenerating retinal pigment epithelium (RPE) cells or may form neurotrophic factors. In this study we have investigated the potential of subretinally transplanted embryonic stem cells to prevent the genetically determined photoreceptor cell degeneration in the RCS rat. Embryonic stem cells from the inner cell mass of the mouse blastocyst were allowed to differentiate to neural precursor cells in vitro and were then transplanted into the subretinal space of 20-day-old RCS rats. Transplanted and sham-operated rats were sacrificed 2 months following cell transplantation. The eyes were enucleated and photoreceptor degeneration was quantified by analyzing and determining the thickness of the outer nuclear layer by light and electron microscopy. In the eyes transplanted with embryonic cells up to 8 rows of photoreceptor cell nuclei were observed, whereas in nontreated control eyes the outer nuclear layer had degenerated completely. Transplantation of embryonic stem cells appears to delay photoreceptor cell degeneration in RCS rats.

  16. Fault-tolerant control with mixed aerodynamic surfaces and RCS jets for hypersonic reentry vehicles

    Directory of Open Access Journals (Sweden)

    Jingjing He

    2017-04-01

    Full Text Available This paper proposes a fault-tolerant strategy for hypersonic reentry vehicles with mixed aerodynamic surfaces and reaction control systems (RCS under external disturbances and subject to actuator faults. Aerodynamic surfaces are treated as the primary actuator in normal situations, and they are driven by a continuous quadratic programming (QP allocator to generate torque commanded by a nonlinear adaptive feedback control law. When aerodynamic surfaces encounter faults, they may not be able to provide sufficient torque as commanded, and RCS jets are activated to augment the aerodynamic surfaces to compensate for insufficient torque. Partial loss of effectiveness and stuck faults are considered in this paper, and observers are designed to detect and identify the faults. Based on the fault identification results, an RCS control allocator using integer linear programming (ILP techniques is designed to determine the optimal combination of activated RCS jets. By treating the RCS control allocator as a quantization element, closed-loop stability with both continuous and quantized inputs is analyzed. Simulation results verify the effectiveness of the proposed method.

  17. Coronary angiography using synchrotron radiation

    International Nuclear Information System (INIS)

    Akatsuka, Takao; Hiranaka, Yukio; Takeda, Tohru; Hyodo, Kazuyuki.

    1990-01-01

    Invasive coronary angiography is the imaging technique of choice for diagnosis of ischemic heart disease. Recently, the application of synchrotron radiation in coronary angiography has been investigated in the world, with the aim of developing the noninvasive technique for visualizing the heart. In this article, backgrounds and present situation of coronary angiography using synchrotron radiation are reviewed. Firstly, visual imaging techniques of the cardiovascular system are discussed in terms of angiography and digital subtraction angiography (DSA). Conventional temporal, energy, and hybrid subtraction modes used in DSA are referred to. Secondly, the application of synchrotron radiation is presented, focusing on the property of synchrotron radiation and K-edge subtraction angiography. Two kinds of synchrotron radiation beam methods are outlined. Interpretation of image data and various subtraction procedures remain unestablished. There is much to be done before coronary angiography using synchrotron radiation comes into a clinical practice. (N.K.)

  18. An Ultra-wideband and Polarization-independent Metasurface for RCS Reduction.

    Science.gov (United States)

    Su, Pei; Zhao, Yongjiu; Jia, Shengli; Shi, Wenwen; Wang, Hongli

    2016-02-11

    In this paper, an ultra-wideband and polarization-independent metasurface for radar cross section (RCS) reduction is proposed. The unit cell of the metasurface operates in a linear cross-polarization scheme in a broad band. The phase and amplitude of cross-polarized reflection can be separately controlled by its geometry and rotation angle. Based on the diffuse reflection theory, a 3-bit coding metasurface is designed to reduce the RCS in an ultra-wide band. The wideband property of the metasurface benefits from the wideband cross polarization conversion and flexible phase modulation. In addition, the polarization-independent feature of the metasurface is achieved by tailoring the rotation angle of each element. Both the simulated and measured results demonstrate that the proposed metasurface can reduce the RCS significantly in an ultra-wide frequency band for both normal and oblique incidences, which makes it promising in the applications such as electromagnetic cloaking.

  19. Parallel Computation of RCS of Electrically Large Platform with Coatings Modeled with NURBS Surfaces

    Directory of Open Access Journals (Sweden)

    Ying Yan

    2012-01-01

    Full Text Available The significance of Radar Cross Section (RCS in the military applications makes its prediction an important problem. This paper uses large-scale parallel Physical Optics (PO to realize the fast computation of RCS to electrically large targets, which are modeled by Non-Uniform Rational B-Spline (NURBS surfaces and coated with dielectric materials. Some numerical examples are presented to validate this paper’s method. In addition, 1024 CPUs are used in Shanghai Supercomputer Center (SSC to perform the simulation of a model with the maximum electrical size 1966.7 λ for the first time in China. From which, it can be found that this paper’s method can greatly speed the calculation and is capable of solving the real-life problem of RCS prediction.

  20. Experimental Results and Numerical Simulation of the Target RCS using Gaussian Beam Summation Method

    Directory of Open Access Journals (Sweden)

    Ghanmi Helmi

    2018-05-01

    Full Text Available This paper presents a numerical and experimental study of Radar Cross Section (RCS of radar targets using Gaussian Beam Summation (GBS method. The purpose GBS method has several advantages over ray method, mainly on the caustic problem. To evaluate the performance of the chosen method, we started the analysis of the RCS using Gaussian Beam Summation (GBS and Gaussian Beam Launching (GBL, the asymptotic models Physical Optic (PO, Geometrical Theory of Diffraction (GTD and the rigorous Method of Moment (MoM. Then, we showed the experimental validation of the numerical results using experimental measurements which have been executed in the anechoic chamber of Lab-STICC at ENSTA Bretagne. The numerical and experimental results of the RCS are studied and given as a function of various parameters: polarization type, target size, Gaussian beams number and Gaussian beams width.

  1. Compact synchrotron radiation source

    International Nuclear Information System (INIS)

    Liu, N.; Wang, T.; Tian, J.; Lin, Y.; Chen, S.; He, W.; Hu, Y.; Li, Q.

    1985-01-01

    A compact 800 MeV synchrotron radiation source is discussed. The storage ring has a circumference of 30.3 m, two 90 degree and four 45 degree bending magnet sections, two long straight sections and four short straight sections. The radius of the bending magnet is 2.224m. The critical wave length is 24A. The injector is a 15 Mev Microtron Electrons are accelerated from 15 Mev to 800 Mev by ramping the field of the ring. The expected stored current will be around 100 ma

  2. The synchrotron radiation

    International Nuclear Information System (INIS)

    Chevallier, P.

    1994-01-01

    Synchrotron Radiation is a fantastic source of electromagnetic radiation the energy spectrum of which spreads continuously from the far infrared to hard X-rays. For this reason a wide part of the scientific community, fundamentalists as well as industry, is concerned by its use. We shall describe here the main properties of this light source and give two examples of application in the field of characterization of materials: EXAFS (Extended X-Ray Absorption Fine Structure) and X-ray fluorescence. (author). 8 figs., 21 refs

  3. Synchrotron Moessbauer reflectometry

    Energy Technology Data Exchange (ETDEWEB)

    Nagy, D.L.; Bottyan, L.; Deak, L.; Szilagyi, E. [KFKI Research Institute for Particle and Nuclear Physics (Hungary); Spiering, H. [Johannes Gutenberg Universitaet Mainz, Institut fuer Anorganische und Analytische Chemie (Germany); Dekoster, J.; Langouche, G. [K.U. Leuven, Instituut voor Kern- en Stralingsfysica (Belgium)

    2000-07-15

    Grazing incidence nuclear resonant scattering of synchrotron radiation can be applied to perform depth-selective phase analysis and to determine the isotopic and magnetic structure of thin films and multilayers. Principles and recent experiments of this new kind of reflectometry are briefly reviewed. Methodological aspects are discussed. Model calculations demonstrate how the orientations of the sublattice magnetisation in ferro- and antiferromagnetic multilayers affect time-integral and time-differential spectra. Experimental examples show the efficiency of the method in investigating finite-stacking, in-plane and out-of-plane anisotropy and spin-flop effects in magnetic multilayers.

  4. Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk.

    Science.gov (United States)

    Vollrath, D; Feng, W; Duncan, J L; Yasumura, D; D'Cruz, P M; Chappelow, A; Matthes, M T; Kay, M A; LaVail, M M

    2001-10-23

    The Royal College of Surgeons (RCS) rat is a widely studied animal model of retinal degeneration in which the inability of the retinal pigment epithelium (RPE) to phagocytize shed photoreceptor outer segments leads to a progressive loss of rod and cone photoreceptors. We recently used positional cloning to demonstrate that the gene Mertk likely corresponds to the retinal dystrophy (rdy) locus of the RCS rat. In the present study, we sought to determine whether gene transfer of Mertk to a RCS rat retina would result in correction of the RPE phagocytosis defect and preservation of photoreceptors. We used subretinal injection of a recombinant replication-deficient adenovirus encoding rat Mertk to deliver the gene to the eyes of young RCS rats. Electrophysiological assessment of animals 30 days after injection revealed an increased sensitivity of treated eyes to low-intensity light. Histologic and ultrastructural assessment demonstrated substantial sparing of photoreceptors, preservation of outer segment structure, and correction of the RPE phagocytosis defect in areas surrounding the injection site. Our results provide definitive evidence that mutation of Mertk underlies the RCS retinal dystrophy phenotype, and that the phenotype can be corrected by treatment of juvenile animals. To our knowledge, this is the first demonstration of complementation of both a functional cellular defect (phagocytosis) and a photoreceptor degeneration by gene transfer to the RPE. These results, together with the recent discovery of MERTK mutations in individuals with retinitis pigmentosa, emphasize the importance of the RCS rat as a model for gene therapy of diseases that arise from RPE dysfunction.

  5. Synchrotron light beam and a synchrotron light experiment facility

    International Nuclear Information System (INIS)

    Ando, Masami

    1980-01-01

    In the National Laboratory for High Energy Physics, about two years ago, the requirements of synchrotron light beam in respective measuring instruments were discussed. Then, also the arrangement (lattice) of a storage ring, the nature of synchrotron light beam, a synchrotron light experiment facility and the arrangement of the beam lines were studied. During the period of two years since then, due to the changes in the circumstances, the design of the lattice was altered. Accordingly, the arrangement of the beam lines and of measuring instruments were largely changed. At this point, the results of discussions in various meetings are described, though they may still be subject to future changes, with due consideration to beam, environment and beam lines required for the design of the measuring instruments: (1) storage ring and synchrotron light beam, (2) requirements on small beam size and beam stability, (3) a synchrotron light experiment facility. (J.P.N.)

  6. Classical and modern power spectrum estimation for tune measurement in CSNS RCS

    International Nuclear Information System (INIS)

    Yang Xiaoyu; Xu Taoguang; Fu Shinian; Zeng Lei; Bian Xiaojuan

    2013-01-01

    Precise measurement of betatron tune is required for good operating condition of CSNS RCS. The fractional part of betatron tune is important and it can be measured by analyzing the signals of beam position from the appointed BPM. Usually these signals are contaminated during the acquisition process, therefore several power spectrum methods are used to improve the frequency resolution. In this article classical and modern power spectrum methods are used. In order to compare their performance, the results of simulation data and IQT data from J-PARC RCS are discussed. It is shown that modern power spectrum estimation has better performance than the classical ones, though the calculation is more complex. (authors)

  7. TMI-2 RCS activity and solids loading from aggressive defueling techniques

    International Nuclear Information System (INIS)

    Baston, V.F.; Hofstetter, K.J.

    1987-01-01

    One of the tasks performed in support of defueling operations has involved mechanical degradation of resolidified material (core crust layer) utilizing the core drilling equipment. Prior to actual drilling operations, an engineering estimate was made for the anticipated increase in radioactivity and particulate loading to the Three Mile Island Unit 2 (TMI-2) reactor coolant system (RCS). Predictions for RCS activity and particulate loading increases were important to evaluate the cleanup requirements for the defueling water cleanup system to minimize both the dose rates for defueling personnel and water turbidity

  8. Synchrotron Elettra. Status and perspectives

    International Nuclear Information System (INIS)

    Remec, I.

    1992-01-01

    Synchrotron radiation and the possibilities for its applications are shortly presented. Elettra, the third generation synchrotron, now under construction in Trieste, Italy, is briefly described and its main characteristics are given. Current activities in Slovenia, related to Elettra, are presented. (author) [sl

  9. Basis of medical accelerator. Synchrotron

    International Nuclear Information System (INIS)

    Kawachi, Kiyomitsu

    2014-01-01

    On the synchrotron as a medical accelerator, this paper introduces the basic principle, basic techniques and the like. The accelerator, when synchrotron is adopted as an ion beam radiotherapy system, is the composite accelerator composed of ion sources, injector, and synchrotron. This paper introduces the overall structure of synchrotron, and conceptually explains the basic behavior of high-frequency waves and magnetic field of synchrotron, as well as the deflection electromagnet of medical synchrotron and the operation pattern of high-frequency acceleration system. The types of synchrotron can be classified to the function combination type and function separation type, and this paper introduces the features of each type and various types of synchrotrons. It also explains beam dynamics important for ensuring the stability of beams, with a focus on the coordinate system, vertical movement, and lateral movement. In addition, it explains the incidence and outgoing of beams that are important for properly operating the accelerator, with a focus on their techniques. (A.O.)

  10. Experience with synchrotron radiation sources

    International Nuclear Information System (INIS)

    Krinsky, S.

    1987-01-01

    The development of synchrotron radiation sources is discussed, emphasizing characteristics important for x-ray microscopy. Bending magnets, wigglers and undulators are considered as sources of radiation. Operating experience at the national Synchrotron Light Source on the VUV and XRAY storage rings is reviewed, with particular consideration given to achieved current and lifetime, transverse bunch dimensions, and orbit stability. 6 refs., 3 figs

  11. Proton synchrotron accelerator theory

    International Nuclear Information System (INIS)

    Wilson, E.J.N.

    1977-01-01

    This is the text of a series of lectures given as part of the CERN Academic Training Programme and primarily intended for young engineers and technicians in preparation for the running-in of the 400 GeV Super Proton Synchrotron (SPS). Following the definition of basic quantities, the problems of betatron motion and the effect of momentum spread and orbital errors on the transverse motion of the beam are reviewed. Consideration is then given to multipole fields, chromaticity and non-linear resonances. After dealing with basic relations governing longitudinal beam dynamics, the space-charge, resistive-wall and other collective effects are treated, with reference to precautions in the SPS to prevent their occurrence. (Auth.)

  12. Changes in intrinsic excitability of ganglion cells in degenerated retinas of RCS rats

    Directory of Open Access Journals (Sweden)

    Yi-Ming Ren

    2018-05-01

    Full Text Available AIM: To evaluate the intrinsic excitability of retinal ganglion cells (RGCs in degenerated retinas. METHODS: The intrinsic excitability of various morphologically defined RGC types using a combination of patch-clamp recording and the Lucifer yellow tracer in retinal whole-mount preparations harvested from Royal College of Surgeons (RCS rats, a common retinitis pigmentosa (RP model, in a relatively late stage of retinal degeneration (P90 were investigated. Several parameters of RGC morphologies and action potentials (APs were measured and compared to those of non-dystrophic control rats, including dendritic stratification, dendritic field diameter, peak amplitude, half width, resting membrane potential, AP threshold, depolarization to threshold, and firing rates. RESULTS: Compared with non-dystrophic control RGCs, more depolarizations were required to reach the AP threshold in RCS RGCs with low spontaneous spike rates and in RCS OFF cells (especially A2o cells, and RCS RGCs maintained their dendritic morphologies, resting membrane potentials and capabilities to generate APs. CONCLUSION: RGCs are relatively well preserved morphologically and functionally, and some cells are more susceptible to decreased excitability during retinal degeneration. These findings provide valuable considerations for optimizing RP therapeutic strategies.

  13. A comparison on radar range profiles between in-flight measurements and RCS-predictions

    NARCIS (Netherlands)

    Heiden, R. van der; Ewijk, L.J. van; Groen, F.C.A.

    1998-01-01

    The validation of Radar Cross Section (RCS) prediction techniques against real measurements is crucial to acquire confidence in predictions when measurements are nut available. In this paper we present the results of a comparison on one-dimensional signatures, i.e. radar range profiles. The profiles

  14. Observations of a cold front with strong vertical undulations during the ARM RCS-IOP

    Energy Technology Data Exchange (ETDEWEB)

    Starr, D.O`C.; Whiteman, D.N. [Goddard Space Flight Center, Greenbelt, MD (United States); Melfi, S.H. [Univ. of Maryland, Baltimore, MD (United States)] [and others

    1996-04-01

    Passage of a cold front was observed on the night of April 14-15, 1994, during the Atmospheric Radiation Measurement (ARM) Remote Cloud Sensing (RCS) Intensive Observatios Period (IOP) at the Southern Great Plains Cloud and Radiation Testbed (CART) site near Lamont, Oklahoma. The observations are described.

  15. Investigation of 3-D RCS Image formation of ships using ISAR

    CSIR Research Space (South Africa)

    Lord, RT

    2006-05-01

    Full Text Available Conventional Inverse Synthetic Aperture Radar (ISAR) utilises the rotational motion of a target such as a ship or an aircraft to obtain a 2-D image of the target’s radar cross section (RCS) profile from a coherent radar system. This concept can...

  16. Layer-specific blood-flow MRI of retinitis pigmentosa in RCS rats☆

    Science.gov (United States)

    Li, Guang; Garza, Bryan De La; Shih, Yen-Yu I.; Muir, Eric R.; Duong, Timothy Q.

    2013-01-01

    The Royal College of Surgeons (RCS) rat is an established animal model of retinitis pigmentosa, a family of inherited retinal diseases which starts with loss of peripheral vision and progresses to eventual blindness. Blood flow (BF), an important physiological parameter, is intricately coupled to metabolic function under normal physiological conditions and is perturbed in many neurological and retinal diseases. This study reports non-invasive high-resolution MRI (44 × 44 × 600 μm) to image quantitative retinal and choroidal BF and layer-specific retinal thicknesses in RCS rat retinas at different stages of retinal degeneration compared with age-matched controls. The unique ability to separate retinal and choroidal BF was made possible by the depth-resolved MRI technique. RBF decreased with progressive retinal degeneration, but ChBF did not change in RCS rats up to post-natal day 90. We concluded that choroidal and retinal circulations have different susceptibility to progressive retinal degeneration in RCS rats. Layer-specific retinal thickness became progressively thinner and was corroborated by histological analysis in the same animals. MRI can detect progressive anatomical and BF changes during retinal degeneration with laminar resolution. PMID:22721720

  17. Layer-specific blood-flow MRI of retinitis pigmentosa in RCS rats.

    Science.gov (United States)

    Li, Guang; De La Garza, Bryan; Shih, Yen-Yu I; Muir, Eric R; Duong, Timothy Q

    2012-08-01

    The Royal College of Surgeons (RCS) rat is an established animal model of retinitis pigmentosa, a family of inherited retinal diseases which starts with loss of peripheral vision and progresses to eventual blindness. Blood flow (BF), an important physiological parameter, is intricately coupled to metabolic function under normal physiological conditions and is perturbed in many neurological and retinal diseases. This study reports non-invasive high-resolution MRI (44 × 44 × 600 μm) to image quantitative retinal and choroidal BF and layer-specific retinal thicknesses in RCS rat retinas at different stages of retinal degeneration compared with age-matched controls. The unique ability to separate retinal and choroidal BF was made possible by the depth-resolved MRI technique. RBF decreased with progressive retinal degeneration, but ChBF did not change in RCS rats up to post-natal day 90. We concluded that choroidal and retinal circulations have different susceptibility to progressive retinal degeneration in RCS rats. Layer-specific retinal thickness became progressively thinner and was corroborated by histological analysis in the same animals. MRI can detect progressive anatomical and BF changes during retinal degeneration with laminar resolution. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. Dynamic RCS Simulation of a Missile Target Group Based on the High-frequency Asymptotic Method

    Directory of Open Access Journals (Sweden)

    Zhao Tao

    2014-04-01

    Full Text Available To simulate dynamic Radar Cross Section (RCS of missile target group, an efficient RCS prediction approach is proposed based on the high-frequency asymptotic theory. The minimal energy trajectory and coordinate transformation is used to get trajectories of the missile, decoys and roll booster, and establish the dynamic scene for the separate procedure of the target group, and the dynamic RCS including specular reflection, edge diffraction and multi-reflection from the target group are obtained by Physical Optics (PO, Equivalent Edge Currents (EEC and Shooting-and-Bouncing Ray (SBR methods. Compared with the dynamic RCS result with the common interpolation method, the proposed method is consistent with the common method when the targets in the scene are far away from each other and each target is not sheltered by others in the incident direction. When the target group is densely distributed and the shelter effect can not be neglected, the interpolation method is extremely difficult to realize, whereas the proposed method is successful.

  19. Glow experiment documentation of OMS/RCS pod and vertical stabilizer

    Science.gov (United States)

    1982-01-01

    Glow experiment documentation of one of the orbital maneuvering system (OMS) reaction control system (RCS) pods and a portion of the vertical stabilizer shows chemoluminescent effectresulting from atomic oxygen impacting the spacecraft and building to the point that the atomic oxygen atoms combine to form molecules of oxygen. The Image Intensifier on NIKON 35mm camera was used to record the glow.

  20. Glow experiment documentation of OMS/RCS pods and vertical stabilizer

    Science.gov (United States)

    1982-01-01

    Glow experiment documentation of orbital maneuvering system (OMS) reaction control system (RCS) pods and vertical stabilizer shows chemo-luminescent effect resulting from atomic oxygen impacting the spacecraft and building to the point that the atomic oxygen atoms combine to form molecules of oxygen. Image intensifier on NIKON 35mm camera was used to record glow on vertical tail and OMS pods.

  1. Bcl-2 expression during the development and degeneration of RCS rat retinae.

    Science.gov (United States)

    Sharma, R K

    2001-12-14

    In various hereditary retinal degenerations, including that in Royal College of Surgeons (RCS) rats, the photoreceptors ultimately die by apoptosis. Bcl-2 is one of the genes, which regulates apoptosis and is thought to promote survival of cells. This study has investigated the developmental expression of Bcl-2 in RCS rat, which is a well-studied animal model for hereditary retinal degeneration. An antibody against Bcl-2 was used for its immunohistochemical localization in dystrophic RCS rat retinae from postnatal (PN) days 4, 7, 13, 35, 45, 70, 202 and 14 months. Results were compared with Bcl-2 localization in congenic non-dystrophic rats from PN 4, 7, 13, 44, 202 and 14 months. Bcl-2 immunoreactivity in non-dystrophic retinae was already present in PN 4 retinae in the nerve fiber layer (presumably in the endfeet of immature Müller cells) and in the proximal parts of certain radially aligned neuroepithelial cells/immature Müller cell radial processes. With increasing age the immunoreactivity in relatively more mature Müller cell radial processes spread distally towards the outer retina and between PN 13 and 44 it reached the adult distribution. No cell bodies in the ganglion cell layer were found to be immunoreactive. Expression of Bcl-2 immunoreactivity in dystrophic RCS rat retinae closely resembled that of non-dystrophic retinae. No immunoreactivity was seen in photoreceptors or retinal pigment epithelium in dystrophic or non-dystrophic retinae. In conclusion, Bcl-2 expression is not altered, either in terms of its chronology or the cell type expressing it, during retinal degeneration in RCS rats.

  2. The analysis of SCS return momentum effects on the RCS water level during mid-loop operations

    Energy Technology Data Exchange (ETDEWEB)

    swang Seo, J.; Young Yang, J.; Tack Hwang, S. [Seoul National Univ. (Korea, Republic of)

    1995-09-01

    An accurate prediction of Reactor Coolant System (RCS) water levels is of importance in the determination of allowable operating range to ensure the safety during the mid-loop operations. However, complex hydraulic phenomena induced by Shutdown Cooling System (SCS) return momentum cause different water levels from those in the loop where the water level indicators are located. This was apparantly observed at the pre-core cold hydro test of the Younggwang Nuclear Unit 3 (YGN 3) in Korea. In this study, in order to analytically understand the effect of the SCS return momentum on the RCS water level and its general trend, a model using one-dimensional momentum equation, hydraulic jump, Bernoulli equation, flow resistance coefficient, and total water volume conservation has been developed to predict the RCS water levels at various RCS locations during the mid-loop conditions and the simulation results were compared with the test data. The analysis shows that the hydraulic jump in the operating cold legs in conjunction with the momentum loss throughout the RCS is the main cause creating the water level differences at various RCS locations. The prediction results provide good explanations for the test data and show the significant effect of the SCS return momentum on the RCS water levels.

  3. The analysis of SCS return momentum effects on the RCS water level during mid-loop operations

    International Nuclear Information System (INIS)

    swang Seo, J.; Young Yang, J.; Tack Hwang, S.

    1995-01-01

    An accurate prediction of Reactor Coolant System (RCS) water levels is of importance in the determination of allowable operating range to ensure the safety during the mid-loop operations. However, complex hydraulic phenomena induced by Shutdown Cooling System (SCS) return momentum cause different water levels from those in the loop where the water level indicators are located. This was apparantly observed at the pre-core cold hydro test of the Younggwang Nuclear Unit 3 (YGN 3) in Korea. In this study, in order to analytically understand the effect of the SCS return momentum on the RCS water level and its general trend, a model using one-dimensional momentum equation, hydraulic jump, Bernoulli equation, flow resistance coefficient, and total water volume conservation has been developed to predict the RCS water levels at various RCS locations during the mid-loop conditions and the simulation results were compared with the test data. The analysis shows that the hydraulic jump in the operating cold legs in conjunction with the momentum loss throughout the RCS is the main cause creating the water level differences at various RCS locations. The prediction results provide good explanations for the test data and show the significant effect of the SCS return momentum on the RCS water levels

  4. Synchrotron light source data book

    International Nuclear Information System (INIS)

    Murphy, J.

    1989-01-01

    The ''Synchrotron Light Source Data Book'' is as its name implies a collection of data on existing and planned synchrotron light sources. The intention was to provide a compendium of tools for the design of electron storage rings as synchrotron radiation sources. The slant is toward the accelerator physicist as other booklets such as the X-ray Data Booklet, edited by D. Vaughan (LBL PUB-490), address the 'use' of synchrotron radiation. It is hoped that the booklet serves as a pocket sized reference to facilitate back of the envelope type calculations. It contains some useful formulae in 'practical units' and a brief description of many of the existing and planned light source lattices

  5. Biomedical applications of synchrotron radiation

    International Nuclear Information System (INIS)

    Kwiatek, W.M.; Galka, M.; Hanson, A.L.; Paluszkiewicz, Cz.; Cichocki, T.

    2001-01-01

    Synchrotron radiation techniques application in medical diagnostics have been presented especially for: trace element analysis in tissues, elemental mapping, chemical speciation at trace levels, chemical structure determination. Presented techniques are very useful for early cancer discovery

  6. Inverse comptonization vs. thermal synchrotron

    International Nuclear Information System (INIS)

    Fenimore, E.E.; Klebesadel, R.W.; Laros, J.G.

    1983-01-01

    There are currently two radiation mechanisms being considered for gamma-ray bursts: thermal synchrotron and inverse comptonization. They are mutually exclusive since thermal synchrotron requires a magnetic field of approx. 10 12 Gauss whereas inverse comptonization cannot produce a monotonic spectrum if the field is larger than 10 11 and is too inefficient relative to thermal synchrotron unless the field is less than 10 9 Gauss. Neither mechanism can explain completely the observed characteristics of gamma-ray bursts. However, we conclude that thermal synchrotron is more consistent with the observations if the sources are approx. 40 kpc away whereas inverse comptonization is more consistent if they are approx. 300 pc away. Unfortunately, the source distance is still not known and, thus, the radiation mechanism is still uncertain

  7. Regions compete for French synchrotron

    CERN Multimedia

    2000-01-01

    Ten regions in France have placed bids to host the planned national synchrotron Soleil. Leading contenders include a joint bid from Ile-de-France and Essonne for Orsay, offering FF 1 billion towards the construction costs (2 paragraphs).

  8. Reshuffle lifts French synchrotron hopes

    CERN Multimedia

    McCabe, H

    2000-01-01

    The sacking of Claude Allegre as research minister has raised doubts over the level of France's promised participation in the construction of Diamond but reawakened French hopes that the synchrotron Soleil may now be built (1 page).

  9. Macromolecular crystallography using synchrotron radiation

    International Nuclear Information System (INIS)

    Bartunik, H.D.; Phillips, J.C.; Fourme, R.

    1982-01-01

    The use of synchrotron X-ray sources in macromolecular crystallography is described. The properties of synchrotron radiation relevant to macromolecular crystallography are examined. The applications discussed include anomalous dispersion techniques, the acquisition of normal and high resolution data, and kinetic studies of structural changes in macromolecules; protein data are presented illustrating these applications. The apparatus used is described including information on the electronic detectors, the monitoring of the incident beam and crystal cooling. (U.K.)

  10. Manufacturability of compact synchrotron mirrors

    Science.gov (United States)

    Douglas, Gary M.

    1997-11-01

    While many of the government funded research communities over the years have put their faith and money into increasingly larger synchrotrons, such as Spring8 in Japan, and the APS in the United States, a viable market appears to exist for smaller scale, research and commercial grade, compact synchrotrons. These smaller, and less expensive machines, provide the research and industrial communities with synchrotron radiation beamline access at a portion of the cost of their larger and more powerful counterparts. A compact synchrotron, such as the Aurora-2D, designed and built by Sumitomo Heavy Industries, Ltd. of japan (SHI), is a small footprint synchrotron capable of sustaining 20 beamlines. Coupled with a Microtron injector, with 150 MeV of injection energy, an entire facility fits within a 27 meter [88.5 ft] square floorplan. The system, controlled by 2 personal computers, is capable of producing 700 MeV electron energy and 300 mA stored current. Recently, an Aurora-2D synchrotron was purchased from SHI by the University of Hiroshima. The Rocketdyne Albuquerque Operations Beamline Optics Group was approached by SHI with a request to supply a group of 16 beamline mirrors for this machine. These mirrors were sufficient to supply 3 beamlines for the Hiroshima machine. This paper will address engineering issues which arose during the design and manufacturing of these mirrors.

  11. Using the Consolidated Framework for Implementation Research (CFIR) to produce actionable findings: a rapid-cycle evaluation approach to improving implementation.

    Science.gov (United States)

    Keith, Rosalind E; Crosson, Jesse C; O'Malley, Ann S; Cromp, DeAnn; Taylor, Erin Fries

    2017-02-10

    Much research does not address the practical needs of stakeholders responsible for introducing health care delivery interventions into organizations working to achieve better outcomes. In this article, we present an approach to using the Consolidated Framework for Implementation Research (CFIR) to guide systematic research that supports rapid-cycle evaluation of the implementation of health care delivery interventions and produces actionable evaluation findings intended to improve implementation in a timely manner. To present our approach, we describe a formative cross-case qualitative investigation of 21 primary care practices participating in the Comprehensive Primary Care (CPC) initiative, a multi-payer supported primary care practice transformation intervention led by the Centers for Medicare and Medicaid Services. Qualitative data include observational field notes and semi-structured interviews with primary care practice leadership, clinicians, and administrative and medical support staff. We use intervention-specific codes, and CFIR constructs to reduce and organize the data to support cross-case analysis of patterns of barriers and facilitators relating to different CPC components. Using the CFIR to guide data collection, coding, analysis, and reporting of findings supported a systematic, comprehensive, and timely understanding of barriers and facilitators to practice transformation. Our approach to using the CFIR produced actionable findings for improving implementation effectiveness during this initiative and for identifying improvements to implementation strategies for future practice transformation efforts. The CFIR is a useful tool for guiding rapid-cycle evaluation of the implementation of practice transformation initiatives. Using the approach described here, we systematically identified where adjustments and refinements to the intervention could be made in the second year of the 4-year intervention. We think the approach we describe has broad

  12. Ultra-Wideband RCS Reduction and Gain Enhancement of Aperture-Coupled Antenna Based on Hybrid-FSS

    Directory of Open Access Journals (Sweden)

    L. L. Cong

    2017-12-01

    Full Text Available A novel design of aperture-coupled microstrip antenna with ultra-wideband low radar cross section (RCS is proposed. Hybrid frequency selective surface (FSS structures consisting of two kinds of polarization-dependent folded split ring resonators (PDFSRRs and square patches are utilized to replace the conventional metallic ground. By orthogonally arranging the PDFSRRs in a chessboard-like configuration, the band-stop characteristic contributes to the gain enhancement, while the zero degree points of reflection phase and wave-transmission characteristic are utilized to achieve RCS reduction both in-band and out-of-band. Furthermore, with square patches periodically etched on the bottom of FSS structure, a new zero degree reflection phase is introduced to enhance the effect of RCS reduction. Full wave simulations and measurements demonstrate that the proposed antenna achieves RCS reduction from 1 GHz to 18 GHz and gain enhancement compared with traditional microstrip antenna.

  13. Changes of the vasculature and innervation in the anterior segment of the RCS rat eye.

    Science.gov (United States)

    May, Christian Albrecht

    2011-12-01

    Investigating the anterior eye segment vasculature and innervation of dystrophic RCS rats, two major unique findings were observed: in the iris, young adult animals with retinal dystrophy showed an increase in substance P nerve fibres and a dilation of arterioles and capillaries. This finding continued during ageing. In the pars plana region, the surface covered by venules decreased continuously with age. In older animals, this decrease was parallelled by a local decrease of sympathetic TH-positive nerve fibres supplying these venules. For both conditions, no comparable data exists so far in the literature. They might point to a unique situation in the anterior eye segment of the dystrophic RCS rat. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. Seismic analysis of APR1400 RCS for site envelope using big mass method

    International Nuclear Information System (INIS)

    Kim, J. Y.; Jeon, J. H.; Lee, D. H.; Park, S. H.

    2002-01-01

    One of design concepts of APR1400 is the site envelope considering various soil sites as well as rock site. The KSNP's are constructed on the rock site where only the translational excitations are directly transferred to the plant. On the other hand, the rotational motions affect the responses of the structures in the soil cases. In this study, a Big Mass Method is used to consider rotational motions as excitations at the foundation in addition to translational ones to obtain seismic responses of the APR1400 RCS main components. The seismic analyses for the APR1400 excited simultaneously by translation and rotational motions were performed. The results show that the effect of soil sites is not significant for the design of main components and supports of the RCS, but it may be considerable for the design of reactor vessel internals, piping, and nozzles which have lower natural frequencies

  15. PROCEEDINGS ON SYNCHROTRON RADIATION: China Spallation Neutron Source - an overview of application prospects

    Science.gov (United States)

    Wei, Jie; Fu, Shi-Nian; Tang, Jing-Yu; Tao, Ju-Zhou; Wang, Ding-Sheng; Wang, Fang-Wei; Wang, Sheng

    2009-11-01

    The China Spallation Neutron Source (CSNS) is an accelerator-based multidisciplinary user facility to be constructed in Dongguan, Guangdong, China. The CSNS complex consists of an H- linear accelerator, a rapid cycling synchrotron accelerating the beam to 1.6 GeV, a solid-tungsten target station, and instruments for spallation neutron applications. The facility operates at 25 Hz repetition rate with an initial design beam power of 120 kW and is upgradeable to 500 kW. Construction of the CSNS project will lay the foundation of a leading national research center based on advanced proton-accelerator technology, pulsed neutron-scattering technology, and related programs including muon, fast neutron, and proton applications as well as medical therapy and accelerator-driven subcritical reactor (ADS) applications to serve China's strategic needs in scientific research and technological innovation for the next 30 plus years.

  16. Regulations, Codes, and Standards (RCS) Template for California Hydrogen Dispensing Stations

    Energy Technology Data Exchange (ETDEWEB)

    Rivkin, C.; Blake, C.; Burgess, R.; Buttner, W.; Post, M.

    2012-11-01

    This report explains the Regulations, Codes, and Standards (RCS) requirements for hydrogen dispensing stations in the State of California. The reports shows the basic components of a hydrogen dispensing station in a simple schematic drawing; the permits and approvals that would typically be required for the construction and operation of a hydrogen dispensing station; and a basic permit that might be employed by an Authority Having Jurisdiction (AHJ).

  17. Alterations in NMDA receptor expression during retinal degeneration in the RCS rat.

    Science.gov (United States)

    Gründer, T; Kohler, K; Guenther, E

    2001-01-01

    To determine how a progressive loss of photoreceptor cells and the concomitant loss of glutamatergic input to second-order neurons can affect inner-retinal signaling, glutamate receptor expression was analyzed in the Royal College of Surgeons (RCS) rat, an animal model of retinitis pigmentosa. Immunohistochemistry was performed on retinal sections of RCS rats and congenic controls between postnatal (P) day 3 and the aged adult (up to P350) using specific antibodies against N-methyl-D-aspartate (NMDA) subunits. All NMDA subunits (NR1, NR2A-2D) were expressed in control and dystrophic retinas at all ages, and distinct patterns of labeling were found in horizontal cells, subpopulations of amacrine cells and ganglion cells, as well as in the outer and inner plexiform layer (IPL). NRI immunoreactivity in the inner plexiform layer of adult control retinas was concentrated in two distinct bands, indicating a synaptic localization of NMDA receptors in the OFF and ON signal pathways. In the RCS retina, these bands of NRI immunoreactivity in the IPL were much weaker in animals older than P40. In parallel, NR2B immunoreactivity in the outer plexiform layer (OPL) of RCS rats was always reduced compared to controls and vanished between P40 and P120. The most striking alteration observed in the degenerating retina, however, was a strong expression of NRI immunoreactivity in Müller cell processes in the inner retina which was not observed in control animals and which was present prior to any visible sign of photoreceptor degeneration. The results suggest functional changes in glutamatergic receptor signaling in the dystrophic retina and a possible involvement of Müller cells in early processes of this disease.

  18. An advanced regulator for the helium pressurization systems of the Space Shuttle OMS and RCS

    Science.gov (United States)

    Wichmann, H.

    1973-01-01

    The Space Shuttle Orbit Maneuvering System and Reaction Control System are pressure-fed rocket propulsion systems utilizing earth storable hypergolic propellants and featuring engines of 6000 lbs and 900 lbs thrust, respectively. The helium pressurization system requirements for these propulsion systems are defined and the current baseline pressurization systems are described. An advanced helium pressure regulator capable of meeting both OMS and RCS helium pressurization system requirements is presented and its operating characteristics and predicted performance characteristics are discussed.

  19. [Blue-light induced expression of S-adenosy-L-homocysteine hydrolase-like gene in Mucor amphibiorum RCS1].

    Science.gov (United States)

    Gao, Ya; Wang, Shu; Fu, Mingjia; Zhong, Guolin

    2013-09-04

    To determine blue-light induced expression of S-adenosyl-L-homocysteine hydrolase-like (sahhl) gene in fungus Mucor amphibiorum RCS1. In the random process of PCR, a sequence of 555 bp was obtained from M. amphibiorum RCS1. The 555 bp sequence was labeled with digoxin to prepare the probe for northern hybridization. By northern hybridization, the transcription of sahhl gene was analyzed in M. amphibiorum RCS1 mycelia culture process from darkness to blue light to darkness. Simultaneously real-time PCR method was used to the sahhl gene expression analysis. Compared with the sequence of sahh gene from Homo sapiens, Mus musculus and some fungi species, a high homology of the 555 bp sequence was confirmed. Therefore, the preliminary confirmation has supported that the 555 bp sequence should be sahhl gene from M. amphibiorum RCS1. Under the dark pre-culture in 24 h, a large amounts of transcript of sahhl gene in the mycelia can be detected by northern hybridization and real-time PCR in the condition of 24 h blue light. But a large amounts of transcript of sahhl gene were not found in other detection for the dark pre-culture of 48 h, even though M. amphibiorum RCS1 mycelia were induced by blue light. Blue light can induce the expression of sahhl gene in the vigorous growth of M. amphibiorum RCS1 mycelia.

  20. Spin dynamics in electron synchrotrons

    International Nuclear Information System (INIS)

    Schmidt, Jan Felix

    2017-01-01

    Providing spin polarized particle beams with circular accelerators requires the consideration of depolarizing resonances which may significantly reduce the desired degree of polarization at specific beam energies. The corresponding spin dynamical effects are typically analyzed with numerical methods. In case of electron beams the influence of the emission of synchrotron radiation has to be taken into account. On short timescales, as in synchrotrons with a fast energy ramp or in damping rings, spin dynamics are investigated with spin tracking algorithms. This thesis presents the spin tracking code Polematrix as a versatile tool to study the impact of synchrotron radiation on spin dynamics. Spin tracking simulations have been performed based on the well established particle tracking code Elegant. The numerical studies demonstrate effects which are responsible for beam depolarization: Synchrotron side bands of depolarizing resonances and decoherence of spin precession. Polematrix can be utilized for any electron accelerator with minimal effort as it imports lattice files from the tracking programs MAD-X or Elegant. Polematrix has been published as open source software. Currently, the Electron Stretcher Accelerator ELSA at Bonn University is the only electron synchrotron worldwide providing a polarized beam. Integer and intrinsic depolarizing resonances are compensated with dedicated countermeasures during the fast energy ramp. Polarization measurements from ELSA demonstrate the particular spin dynamics of electrons and confirm the results of the spin tracking code Polematrix.

  1. Uneven-Layered Coding Metamaterial Tile for Ultra-wideband RCS Reduction and Diffuse Scattering.

    Science.gov (United States)

    Su, Jianxun; He, Huan; Li, Zengrui; Yang, Yaoqing Lamar; Yin, Hongcheng; Wang, Junhong

    2018-05-25

    In this paper, a novel uneven-layered coding metamaterial tile is proposed for ultra-wideband radar cross section (RCS) reduction and diffuse scattering. The metamaterial tile is composed of two kinds of square ring unit cells with different layer thickness. The reflection phase difference of 180° (±37°) between two unit cells covers an ultra-wide frequency range. Due to the phase cancellation between two unit cells, the metamaterial tile has the scattering pattern of four strong lobes deviating from normal direction. The metamaterial tile and its 90-degree rotation can be encoded as the '0' and '1' elements to cover an object, and diffuse scattering pattern can be realized by optimizing phase distribution, leading to reductions of the monostatic and bi-static RCSs simultaneously. The metamaterial tile can achieve -10 dB RCS reduction from 6.2 GHz to 25.7 GHz with the ratio bandwidth of 4.15:1 at normal incidence. The measured and simulated results are in good agreement and validate the proposed uneven-layered coding metamaterial tile can greatly expanding the bandwidth for RCS reduction and diffuse scattering.

  2. An investigation of the RCS (radar cross section) computation of grid cavities

    International Nuclear Information System (INIS)

    Sabihi, Ahmad

    2014-01-01

    In this paper, the aperture of a cavity is covered by a metallic grid net. This metallic grid is to reduce RCS deduced by impinging radar ray on the aperture. A radar ray incident on a grid net installed on a cavity may create six types of propagation. 1-Incident rays entering inside the cavity and backscattered from it.2-Incidebnt rays on the grid net and created reection rays as an array of scatterers. These rays may create a wave with phase difference of 180 degree with respect to the exiting rays from the cavity.3-Incident rays on the grid net create surface currents owing on the net and make travelling waves, which regenerate the magnetic and electric fields. These fields make again propagated waves against incident ones.4-Creeping waves.5-Diffracted rays due to leading edges of net’s elements.6-Mutual impedance among elements of the net could be effective on the resultant RCS. Therefore, the author compares the effects of three out of six properties to a cavity without grid net. This comparison shows that RCS prediction of cavity having a grid net is much more reduced than that of without one

  3. An investigation of the RCS (radar cross section) computation of grid cavities

    Energy Technology Data Exchange (ETDEWEB)

    Sabihi, Ahmad [Department of Mathematical Sciences, Sharif University of Technology, Tehran (Iran, Islamic Republic of)

    2014-12-10

    In this paper, the aperture of a cavity is covered by a metallic grid net. This metallic grid is to reduce RCS deduced by impinging radar ray on the aperture. A radar ray incident on a grid net installed on a cavity may create six types of propagation. 1-Incident rays entering inside the cavity and backscattered from it.2-Incidebnt rays on the grid net and created reection rays as an array of scatterers. These rays may create a wave with phase difference of 180 degree with respect to the exiting rays from the cavity.3-Incident rays on the grid net create surface currents owing on the net and make travelling waves, which regenerate the magnetic and electric fields. These fields make again propagated waves against incident ones.4-Creeping waves.5-Diffracted rays due to leading edges of net’s elements.6-Mutual impedance among elements of the net could be effective on the resultant RCS. Therefore, the author compares the effects of three out of six properties to a cavity without grid net. This comparison shows that RCS prediction of cavity having a grid net is much more reduced than that of without one.

  4. Location Privacy on DVB-RCS using a “Spatial-Timing” Approach

    Directory of Open Access Journals (Sweden)

    A. Aggelis

    2011-09-01

    Full Text Available DVB-RCS synchronization scheme on the Return Channel requires the RCSTs to be programmed with their location coordinates with an accuracy of no more than a few kilometers. RCSTs use this location information in their ranging calculation to the servicing satellite. For certain users this location information disclosure to the network operator can be seen as a serious security event. Recent work of the authors overcame this requirement by cloaking the location of an RCST in such a way (based on "spatial/geometric" symmetries of the network that the respective ranging calculations are not affected. In this work we argue that timing tolerances in the Return Channel synchronization scheme, accepted by the DVB-RCS standard, can be used in combination to the "spatial" method, further enhancing the location privacy of an RCST. Theoretical findings of the proposed "spatial-timing" approach were used to develop a practical method that can be used by workers in the field. Finally this practical method was successfully tested on a real DVB-RCS system.

  5. Intraocular gene transfer of ciliary neurotrophic factor rescues photoreceptor degeneration in RCS rats.

    Science.gov (United States)

    Huang, Shun-Ping; Lin, Po-Kang; Liu, Jorn-Hon; Khor, Chin-Ni; Lee, Yih-Jing

    2004-01-01

    Ciliary neurotrophic factor (CNTF) is known as an important factor in the regulation of retinal cell growth. We used both recombinant CNTF and an adenovirus carrying the CNTF gene to regulate retinal photoreceptor expression in a retinal degenerative animal, Royal College of Surgeons (RCS) rats. Cells in the outer nuclear layer of the retinae from recombinant-CNTF-treated, adenoviral-CNTF-treated, saline-operated, and contralateral untreated preparations were examined for those exhibiting CNTF photoreceptor protective effects. Cell apoptosis in the outer nuclear layer of the retinae was also detected. It was found that CNTF had a potent effect on delaying the photoreceptor degeneration process in RCS rats. Furthermore, adenovirus CNTF gene transfer was proven to be better at rescuing photoreceptors than that when using recombinant CNTF, since adenoviral CNTF prolonged the photoreceptor protection effect. The function of the photoreceptors was also examined by taking electroretinograms of different animals. Adenoviral-CNTF-treated eyes showed better retinal function than did the contralateral control eyes. This study indicates that adenoviral CNTF effectively rescues degenerating photoreceptors in RCS rats. Copyright 2004 National Science Council, ROC and S. Karger AG, Basel

  6. Preservation of photoreceptors in dystrophic RCS rats following allo- and xenotransplantation of IPE cells.

    Science.gov (United States)

    Thumann, Gabriele; Salz, Anna Katharina; Walter, Peter; Johnen, Sandra

    2009-03-01

    To examine whether iris pigment epithelial (IPE) cells transplanted into the subretinal space of Royal College of Surgeons (RCS) rats have the ability to rescue photoreceptors. Rat IPE (rIPE) or human IPE (hIPE) cells were transplanted subretinally in 23-day-old RCS rats. Sham injection and transplantation of ARPE-19 cells served as controls. After 12 weeks, eyes were evaluated for photoreceptor survival by morphometric analysis and electron microscopy. Morphometric analysis showed photoreceptor rescue in all transplanted and sham-injected animals (number of photoreceptors/300 microm retina+/-sd: rIPE 41.67 +/- 28; hIPE 29.50 +/- 16; ARPE-19 36.12 +/- 21; sham 16.56 +/- 6) compared to age-matched, control rats (number of photoreceptors/300 microm retina+/-sd: 9.71 +/- 4). Photoreceptor rescue was prominent in IPE cell-transplanted rats and was significantly greater than sham-injected eyes (p = 0.02 for rIPE and p = 0.04 for hIPE). Since IPE cells transplanted into the subretinal space have the ability to rescue photoreceptors from degeneration in the RCS rat without any harmful effects, IPE cells may represent an ideal cell to genetically modify and thus carry essential genetic information for the repair of defects in the subretinal space.

  7. Homeostatic Plasticity Mediated by Rod-Cone Gap Junction Coupling in Retinal Degenerative Dystrophic RCS Rats

    Science.gov (United States)

    Hou, Baoke; Fu, Yan; Weng, Chuanhuang; Liu, Weiping; Zhao, Congjian; Yin, Zheng Qin

    2017-01-01

    Rod-cone gap junctions open at night to allow rod signals to pass to cones and activate the cone-bipolar pathway. This enhances the ability to detect large, dim objects at night. This electrical synaptic switch is governed by the circadian clock and represents a novel form of homeostatic plasticity that regulates retinal excitability according to network activity. We used tracer labeling and ERG recording in the retinae of control and retinal degenerative dystrophic RCS rats. We found that in the control animals, rod-cone gap junction coupling was regulated by the circadian clock via the modulation of the phosphorylation of the melatonin synthetic enzyme arylalkylamine N-acetyltransferase (AANAT). However, in dystrophic RCS rats, AANAT was constitutively phosphorylated, causing rod-cone gap junctions to remain open. A further b/a-wave ratio analysis revealed that dystrophic RCS rats had stronger synaptic strength between photoreceptors and bipolar cells, possibly because rod-cone gap junctions remained open. This was despite the fact that a decrease was observed in the amplitude of both a- and b-waves as a result of the progressive loss of rods during early degenerative stages. These results suggest that electric synaptic strength is increased during the day to allow cone signals to pass to the remaining rods and to be propagated to rod bipolar cells, thereby partially compensating for the weak visual input caused by the loss of rods. PMID:28473754

  8. Contact microscopy with synchrotron radiation

    International Nuclear Information System (INIS)

    Panessa-Warren, B.J.

    1985-10-01

    Soft x-ray contact microscopy with synchrotron radiation offers the biologist and especially the microscopist, a way to morphologically study specimens that could not be imaged by conventional TEM, STEM or SEM methods (i.e. hydrated samples, samples easily damaged by an electron beam, electron dense samples, thick specimens, unstained low contrast specimens) at spatial resolutions approaching those of the TEM, with the additional possibility to obtain compositional (elemental) information about the sample as well. Although flash x-ray sources offer faster exposure times, synchrotron radiation provides a highly collimated, intense radiation that can be tuned to select specific discrete ranges of x-ray wavelengths or specific individual wavelengths which optimize imaging or microanalysis of a specific sample. This paper presents an overview of the applications of x-ray contact microscopy to biological research and some current research results using monochromatic synchrotron radiation to image biological samples. 24 refs., 10 figs

  9. The synchrotron light source ROSY

    International Nuclear Information System (INIS)

    Einfeld, D.; Buettig, H.; Dienel, S.; Glaeser, W.; Goetz, T.; Guratzsch, H.; Hartmann, B.; Janssen, D.; Krug, H.; Linnemann, J.; Matz, W.; Murphy, J.B.; Neumann, W.; Oehme, W.; Picard, M.; Plesko, M.; Proehl, D.; Schlenk, R.; Tomassini, D.; Tyrroff, H.

    1994-01-01

    ROSY, a 3rd generation synchrotron light source, has been proposed to be built at the Research Center Rossendorf/Dresden in Germany. With its low emittance and optimized space for installing insertion devices ROSY will be the first synchrotron radiation source in the 3 GeV range in Europe, dedicated to materials research and industrial application. The critical wavelength of the synchrotron radiation spectra was designed to be 0.15 nm corresponding to a critical photon energy of 8.4 keV. It is proposed to use a ''modified multiple bend achromat'' (MBA) lattice in order to get a compact machine as well as a low emittance. For 3 GeV an emittance smaller than 30π nm rad can be obtained. With a fourfold symmetry and two larger straight sections within the achromatic arcs the circumference is 148 m. 23% of the circumference can be used for installing insertion devices. (orig.)

  10. Rapid Cycling and Its Treatment

    Science.gov (United States)

    ... their career goals. These struggles may contribute to self-esteem problems. That’s why it’s helpful for people with ... more discoveries are expected in the years ahead. Education Mood Disorders Depression Bipolar Disorder Anxiety Screening Center ...

  11. Synchrotron radiation and structural proteomics

    CERN Document Server

    Pechkova, Eugenia

    2011-01-01

    This book presents an overview of the current state of research in both synchrotron radiation and structural proteomics from different laboratories worldwide. The book presents recent research results in the most advanced methods of synchrotron radiation analysis, protein micro- and nano crystallography, X-ray scattering and X-ray optics, coherent X-Ray diffraction, and laser cutting and contactless sample manipulation are described in details. The book focuses on biological applications and highlights important aspects such as radiation damage and molecular modeling.

  12. Atoms, molecules, clusters and synchrotron radiation

    International Nuclear Information System (INIS)

    Kui Rexi; Ju Xin

    1995-01-01

    The importance of synchrotron radiation, especially the third generation synchrotron radiation light source, in atomic, molecular and cluster physics is discussed and some views are presented on new methods which may become available for research in the above fields

  13. PHOTOACOUSTIC SPECTROSCOPY USING A SYNCHROTRON LIGHT SOURCE

    International Nuclear Information System (INIS)

    JACKSON, R.S.; MICHAELIAN, K.H.; HOMES, C.C.

    2001-01-01

    We have investigated the use of a synchrotron as a source for infrared photoacoustic spectroscopy. A synchrotron has an intrinsically high radiance, which is beneficial when photoacoustic spectroscopy is applied to small samples, especially at long wavelengths

  14. Synchrotron X-Ray Footprinting on Tour

    OpenAIRE

    Bohon, Jen; Ralston, Corie; D'Mello, Rhijuta; Gupta, Sayan; Chance, Mark R.

    2014-01-01

    Synchrotron X-ray footprinting resources were investigated at a variety of beamlines and synchrotron facilities to understand their potential for a mobile general user. Results indicate that viable resources exist at each synchrotron investigated such that a prospective user need only provide a simple flow apparatus and sample handling accessories to perform this technique.

  15. DESY: Synchrotron and storage rings

    CERN Multimedia

    1972-01-01

    An improvement programme has been under way for several years at the 7.5 GeV électron synchrotron at DESY. In particular it has been designed to increase the accelerated beam intensity, to achieve better quality of the ejected électron beams and photon beams and to improve machine reliability.

  16. Synchrotron radiation and biomedical imaging

    International Nuclear Information System (INIS)

    Luccio, A.

    1986-08-01

    In this lecture we describe the characteristics of Synchrotron radiation as a source of X rays. We discuss the properties of SR arc sources, wigglers, undulators and the use of backscattering of laser light. Applications to angiography, X ray microscopy and tomography are reviewed. 16 refs., 23 figs

  17. Biological physics and synchrotron radiation

    International Nuclear Information System (INIS)

    Filhol, J.M.; Chavanne, J.; Weckert, E.

    2001-01-01

    This conference deals with the applications of synchrotron radiation to current problems in biology and medicine. Seven sessions take stock on the subject: sources and detectors; inelastic scattering and dynamics; muscle diffraction; reaction mechanisms; macromolecular assemblies; medical applications; imaging and spectroscopy. The document presents the papers abstracts. (A.L.B.)

  18. The Australian synchrotron research program

    International Nuclear Information System (INIS)

    Garrett, R.F.

    1998-01-01

    Full text: The Australian Synchrotron Research Program (ASRP) was established in 1996 under a 5 year grant from the Australian Government, and is managed by ANSTO on behalf of a consortium of Australian universities and research organisations. It has taken over the operation of the Australian National Beamline Facility (ANBF) at the Photon Factory, and has joined two CATS at the Advanced Photon Source: the Synchrotron Radiation Instrumentation CAT (SRI-CAT) and the Consortium for Advanced Radiation Sources (CARS). The ASRP thus manages a comprehensive range of synchrotron radiation research facilities for Australian science. The ANBF is a general purpose hard X-ray beamline which has been in operation at the Photon Factory since 1993. It currently caters for about 35 Australian research teams per year. The facilities available at the ANBF will be presented and the research program will be summarised. The ASRP facilities at the APS comprise the 5 sectors operated by SRI-CAT, BioCARS and ChemMatCARS. A brief description will be given of the ASRP research programs at the APS, which will considerably broaden the scope of Australian synchrotron science

  19. Tandems as injectors for synchrotrons

    International Nuclear Information System (INIS)

    Ruggiero, A.G.

    1993-01-01

    This is a review on the use of tandem electrostatic accelerators for injection and fitting of synchrotrons to accelerate intense beams of heavy ions to relativistic energies. The paper emphasizes the need of operating the tandems in pulsed mode for this application. It has been experimentally demonstrated that at present this type of accelerator still provides the most reliable and best performance. (orig.)

  20. Biological physics and synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Filhol, J M; Chavanne, J [European Synchrotron Radiation Facility, 38 - Grenoble (France); Weckert, E [Hasylab at Desy, Hamburg (Germany); and others

    2001-07-01

    This conference deals with the applications of synchrotron radiation to current problems in biology and medicine. Seven sessions take stock on the subject: sources and detectors; inelastic scattering and dynamics; muscle diffraction; reaction mechanisms; macromolecular assemblies; medical applications; imaging and spectroscopy. The document presents the papers abstracts. (A.L.B.)

  1. Synchrotron radiation in material science

    International Nuclear Information System (INIS)

    Zanotto, E.D.

    1983-01-01

    A brief review on the several experimental techniques (XRD, SAXS, EXAFS, IRRS, etc...) which, utilizing of synchrotron radiation can be applied in glass structural studies, is presented. The major part of these techniques can be also used for studies of other materials such as polymers, metals, etc... (L.C.) [pt

  2. Synchrotron Radiation and Faraday Rotation

    NARCIS (Netherlands)

    Heald, George

    2015-01-01

    Synchrotron radiation and its degree of linear polarization are powerful tracers of magnetic fields that are illuminated by cosmic ray electrons. Faraday rotation of the linearly polarized radiation is induced by intervening line-of-sight magnetic fields that are embedded in ionized plasmas. For

  3. Subretinal electrical stimulation preserves inner retinal function in RCS rat retina.

    Science.gov (United States)

    Ciavatta, Vincent T; Mocko, Julie A; Kim, Moon K; Pardue, Machelle T

    2013-01-01

    Previously, studies showed that subretinal electrical stimulation (SES) from a microphotodiode array (MPA) preserves electroretinography (ERG) b-wave amplitude and regional retinal structure in the Royal College of Surgeons (RCS) rat and simultaneously upregulates Fgf2 expression. This preservation appears to be associated with the increased current produced when the MPA is exposed to ERG test flashes, as weekly ERG testing produces greater neuroprotection than biweekly or no testing. Using an infrared source to stimulate the MPA while avoiding potential confounding effects from exposing the RCS retina to high luminance white light, this study examined whether neuroprotective effects from SES increased with subretinal current in a dose-dependent manner. RCS rats (n=49) underwent subretinal implantation surgery at P21 with MPA devices in one randomly selected eye, and the other eye served as the control. Naïve RCS rats (n=25) were also studied. To increase SES current levels, implanted eyes were exposed to 15 min per session of flashing infrared light (IR) of defined intensity, frequency, and duty cycle. Rats were divided into four SES groups that received ERG testing only (MPA only), about 450 µA/cm2 once per week (Low 1X), about 450 µA/cm2 three times per week (Low 3X), and about 1350 µA/cm2 once per week (High 1X). One eye of the control animals was randomly chosen for IR exposure. All animals were followed for 4 weeks with weekly binocular ERGs. A subset of the eyes was used to measure retina Fgf2 expression with real-time reverse-transcription PCR. Eyes receiving SES showed significant preservation of b-wave amplitude, a- and b-wave implicit times, oscillatory potential amplitudes, and post-receptoral parameters (Vmax and log σ) compared to untreated eyes. All SES-treated eyes had similar preservation, regardless of increased SES from IR light exposure. SES-treated eyes tended to have greater retinal Fgf2 expression than untreated eyes, but Fgf2 expression

  4. Resolution of issues related to alternative RCS injection in the absence of containment sump recirculation

    International Nuclear Information System (INIS)

    Charles L Kling; Stephen S Barshay; Mathew C Jacob; Michael J Friedman

    2005-01-01

    Full text of publication follows: On June 9, 2003 the US NRC issued Bulletin No. 2003-01 that deals with the potential impact of debris blockage on containment sump recirculation at PWRs during a Loss-of-Coolant Accident (LOCA). In response to the bulletin, the Omaha Public Power District (OPPD) is in the process of developing procedural and operational strategies for their Fort Calhoun Station (FCS) to address the issues raised. Westinghouse provided engineering support to OPPD in identifying and resolving issues related to alternative means of supplying safety injection water to the reactor coolant system (RCS) in the absence of containment sump recirculation. Nuclear power plants are designed to protect the core following a LOCA by providing a continuous supply of cooling water to the core. In the long term, the Refueling Water Storage Tank (RWST) inventory will be depleted and core heat removal accomplished via recirculation of water previously injected into the Reactor Coolant System (RCS) and collected in the containment sump. Debris generated within the containment as a result of the impingement of fluid jets in the Zone of Influence (ZOI) of the RCS break and containment wash down may find its way into the containment sump. As the safety injection pumps take suction from the sump, in the recirculation mode of operation, the debris suspended in the sump water could begin to accumulate in the sump screen that is located in the recirculation path. Should sufficient debris accumulate on the sump screen, a flow blockage could potentially develop. This would result in insufficient safety injection pump NPSH, thereby impairing the recirculation mode of injection into RCS. Potential debris blockage and prevention of sump recirculation may be addressed by refilling the RWST with water and injecting this water directly into the core. This paper identifies and attempts to resolve several issues related to this alternative mode of RCS injection. In particular, the

  5. ESTIMATION OF WIDE BAND RADAR CROSS SECTION (RCS OF REGULAR SHAPED OBJECTS USING METHOD OF MOMENTS (MOM

    Directory of Open Access Journals (Sweden)

    M. Madheswaran

    2012-06-01

    Full Text Available Modern fighter aircrafts, ships, missiles etc need to be very low Radar Cross Section (RCS designs, to avoid detection by hostile radars. Hence accurate prediction of RCS of complex objects like aircrafts is essential to meet this requirement. A simple and efficient numerical procedure for treating problems of wide band RCS prediction Perfect Electric Conductor (PEC objects is developed using Method of Moment (MoM. Implementation of MoM for prediction of RCS involves solving Electric Field Integral Equation (EFIE for electric current using the vector and scalar potential solutions, which satisfy the boundary condition that the tangential electric field at the boundary of the PEC body is zero. For numerical purposes, the objects are modeled using planar triangular surfaces patches. Set of special sub-domain type basis functions are defined on pairs of adjacent triangular patches. These basis functions yield a current representation free of line or point charges at sub-domain boundaries. Once the current distribution is obtained, dipole model is used to find Scattering field in free space. RCS can be calculated from the scattered and incident fields. Numerical results for a square plate, a cube, and a sphere are presented over a bandwidth.

  6. The Quantitative Reasoning for College Science (QuaRCS) Assessment in non-Astro 101 Courses II

    Science.gov (United States)

    Kirkman, Thomas W.; Jensen, Ellen

    2017-06-01

    The Quantitative Reasoning for College Science (QuaRCS) Assessment[1] aims to measure the pre-algebra mathematical skills that are often part of "general education" science courses like Astro 101. In four majors STEM classes, we report comparisons between QuaRCS metrics, ACT math, GPAO, and the course grade. In three of four classes QuaRCS QR score and ACT math were statistically significantly correlated (with r˜.6), however in the fourth course —a senior-level microbiology course— there was no statistically significantly correlation (in fact, rPhysics courses showed fractional sigma gains in QR, self-estimated math fluency and math importance, but not all of those increases were statistically significant. Using a QuaRCS map relating the questions to skill areas, we found graph reading, percentages, and proportional reasoning to be the most misunderstood skills in all four courses.[1] QuaRCS, Follette, et al.,2015, DOI: http://dx.doi.org/10.5038/1936-4660.8.2.2

  7. Activation of retinal stem cells in the proliferating marginal region of RCS rats during development of retinitis pigmentosa.

    Science.gov (United States)

    Jian, Qian; Xu, Haiwei; Xie, Hanping; Tian, Chunyu; Zhao, Tongtao; Yin, ZhengQin

    2009-11-06

    Retinal stem cells (RSCs) have been demonstrated at the proliferating marginal regions from the pars plana of ciliary body to the ciliary marginal zone (CMZ) in adult lower vertebrates and mammals. Investigations in the lower vertebrates have provided some evidence that RSCs can proliferate following retinal damage; however, the evidence that this occurs in mammals is not clear. In this study, we explored RSCs proliferation potential of adult mammalian in proliferating marginal regions of Royal College of Surgeons (RCS) rats, an animal model for retinitis pigmentosa (RP). The proliferation was evaluated using BrdU labeling, and Chx-10 as markers to discern progenitor cell of CMZ in Long-Evan's and RCS rats at different postnatal day (PND) after eye opening. We found that few Chx-10 and BrdU labeled cells in the proliferating marginal regions of Long-Evan's rats, which significantly increased in RCS rats at PND30 and PND60. Consistent with this, Chx-10/Vimentin double staining cells in the center retina of RCS rats increased significantly at PND30 after eye opening. In addition, mRNA expression of Shh, Ptch1 and Smo was up-regulated in RCS rats at PND60 compared to age-matched Long-Evan's rats, which revealed Shh/ptc pathway involving in the activation of RSCs. These results suggest that RSCs in the mammalian retinal proliferating marginal regions has the potential to regenerate following degeneration.

  8. Grafting of ARPE-19 and Schwann cells to the subretinal space in RCS rats.

    Science.gov (United States)

    Wang, Shaomei; Lu, Bin; Wood, Patrick; Lund, Raymond D

    2005-07-01

    To study the distribution of the human retinal pigment epithelium (hRPE) cell line ARPE-19 and human Schwann (hSC) cells grafted to the subretinal space of the Royal College of Surgeon (RCS) rat and the relation of graft cell distribution to photoreceptor rescue. Cell suspensions of both donor types were injected into the subretinal space of 3-week-old dystrophic RCS rats through a transscleral approach, human fibroblast and medium were used as control grafts. All animals were maintained on oral cyclosporine. At 1, 2, 4, 6, 15, 28, and 36 weeks after grafting, animals were killed. Human cell-specific markers were used to localize donor cells. Both donor cell types, as revealed by antibodies survived for a substantial time. Their distribution was very different: hRPE cells formed a large clump early on and, with time, spread along the host RPE in a layer one to two cells deep, whereas hSCs formed many smaller clumps, mainly in the subretinal space. Both cells rescued photoreceptors beyond the area of donor cell distribution. The number of surviving cells declined with time. Both hRPE and hSC grafts can survive and rescue photoreceptors for a substantial time after grafting. The number of both donor cell types declined with time, which could be an immune-related problem and/or due to other factors intrinsic to the host RCS retina. The fact that rescue occurred beyond the area of donor cell distribution suggests that diffusible factors are involved, raising the possibility that the two cell types function in a similar manner to rescue photoreceptors.

  9. Research using synchrotron radiation at the National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Thomlinson, W.

    1982-01-01

    The National Synchrotron Light Source (NSLS) is now becoming operational with synchrotron radiation experiments beginning on the 700 MeV VUV electron storage ring. Commissioning of the 2.5 GeV x-ray storage ring has also begun with the experimental program expected to begin in 1983. The current status of the experimental program and instrumentation and the plans for future developments, will be discussed. Although some early results have been obtained on VUV beam lines no attempt will be made in this paper to describe them. Instead, an overview of the beam line characteristics will be given, with an indication of those already operational. In the oral presentation some initial experimental results will be discussed

  10. Cone function studied with flicker electroretinogram during progressive retinal degeneration in RCS rats.

    Science.gov (United States)

    Pinilla, I; Lund, R D; Sauvé, Y

    2005-01-01

    The Royal College of Surgeons (RCS) rat has a primary defect in retinal pigment epithelial cells that leads to the progressive loss of photoreceptors and central visual responsiveness. While most rods are lost by 90 days of age (P90), cones degenerate more slowly, and can be detected anatomically up to 2 years of age, despite massive neuronal death and retinal remodelling. To examine how this progressive degenerative process impacts on cone function, we recorded the electroretingram to white light flashes (1.37 log cd s m(-2)) presented at frequencies ranging from 3 to 50 Hz, under light adapted conditions (29.8 cd m(-2)). Pigmented dystrophic and congenic non-dystrophic RCS rats aged from 18 to 300 days were studied. In all responsive animals at all ages, maximal amplitudes were obtained at 3 Hz. In both non-dystrophic and dystrophic rats, there was an increase from P18 to P21 in response amplitude and critical fusion frequency. After P21, these two parameters declined progressively with age in dystrophic rats. Other changes included prolongation in latency, which was first detected prior to the initiation of amplitude reduction. While phase shifts were also detected in dystrophic RCS rats, they appeared at later degenerative stages. The latest age at which responses could be elicited in dystrophic rats was at P200, with positive waves being replaced by negative deflections. The effect of increments in the intensity of background illumination was tested at P50 in both groups. This caused a diminution in flicker response amplitude and critical fusion frequencies in non-dystrophics, while in dystrophic animals, response amplitudes were reduced only at low frequencies and critical fusion frequencies were unaltered. In conclusion, although dystrophic RCS rats undergo a progressive decline in cone function with age, the flicker responsiveness at P21 is comparable to that of non-dystrophic congenic rats, suggesting normal developmental maturation of the cone system in

  11. Summary of LO2/Ethanol OMS/RCS Technology and Advanced Development 99-2744

    Science.gov (United States)

    Curtis, Leslie A.; Hurlbert, Eric A.

    1999-01-01

    NASA is pursuing non-toxic propellant technologies applicable to RLV and Space Shuttle orbital maneuvering system (OMS) and reaction control system (RCS). The primary objectives of making advancements in an OMS/RCS system are improved safety, reliability, and reduced operations and maintenance cost, while meeting basic operational and performance requirements. An OMS/RCS has a high degree of direct interaction with the vehicle and crew and requires subsystem and components that are compatible with integration into the vehicle with regard to external mold-line, power, and thermal control. In July 1997, a Phase I effort for the technology and advanced development of an upgrade of the space shuttle was conducted to define the system architecture, propellant tank, feed system, RCS thrusters, and OMS engine. Phase I of the project ran from July 1997 to October 1998. Phase II is currently being planned for the development and test of full-scale prototype of the system in 1999 and 2000. The choice of pressure-fed liquid oxygen (LO2) and ethanol is the result of numerous trade studies conducted from 1980 to 1996. Liquid oxygen and ethanol are clean burning, high-density propellants that provide a high degree of commonality with other spacecraft subsystems including life support, power, and thermal control, and with future human exploration and development of space missions. The key to this pressure-fed system is the use of subcooled liquid oxygen at 350 psia. In this approach, there is 80 degrees R of subcooling, which means that boil-off will not occur until the temperature has risen 80 R. The sub-cooling results naturally from loading propellants at 163 R, which is the saturation temperature at 14.7 psia, and then pressurizing to 350 psia on the launch pad. Thermal insulation and conditioning techniques are then used to limit the LO2 temperature to 185 R maximum, and maintain the sub-cooling. The other key is the wide temperature range of ethanol, -173 F to +300 F, which

  12. Yield and seed oil content response of dwarf, rapid-cycling Brassica to nitrogen treatments, planting density, and carbon dioxide enrichment

    Science.gov (United States)

    Frick, J.; Nielsen, S. S.; Mitchell, C. A.

    1994-01-01

    Effects of N level (15 to 30 mM), time of N increase (14 to 28 days after planting), and planting density (1163 to 2093 plants/m2) were determined for crop yield responses of dwarf, rapid-cycling brassica (Brassica napus L., CrGC 5-2, Genome: ACaacc). Crops were grown in solid-matrix hydroponic systems and under controlled-environment conditions, including nonsupplemented (ambient) or elevated CO2 concentrations (998 +/- 12 micromoles mol-1). The highest seed yield rate obtained (4.4 g m-2 day-1) occurred with the lowest N level (15 mM) applied at the latest treatment time (day 28). In all trials, CO2 enrichment reduced seed yield rate and harvest index by delaying the onset of flowering and senescence and stimulating vegetative shoot growth. The highest shoot biomass accumulation rate (55.5 g m-2 day-1) occurred with the highest N level (30 mM) applied at the earliest time (day 14). Seed oil content was not significantly affected by CO2 enrichment. Maximum seed oil content (30% to 34%, dry weight basis) was obtained using the lowest N level (15 mM) initiated at the latest treatment time (day 28). In general, an increase in seed oil content was accompanied by a decrease in seed protein. Seed carbohydrate, moisture, and ash contents did not vary significantly in response to experimental treatments. Effects of N level and time of N increase were consistently significant for most crop responses. Planting density was significant only under elevated CO2 conditions.

  13. Electron beam ion sources for use in second generation synchrotrons for medical particle therapy

    Science.gov (United States)

    Zschornack, G.; Ritter, E.; Schmidt, M.; Schwan, A.

    2014-02-01

    Cyclotrons and first generation synchrotrons are the commonly applied accelerators in medical particle therapy nowadays. Next generation accelerators such as Rapid Cycling Medical Synchrotrons (RCMS), direct drive accelerators, or dielectric wall accelerators have the potential to improve the existing accelerator techniques in this field. Innovative accelerator concepts for medical particle therapy can benefit from ion sources which meet their special requirements. In the present paper we report on measurements with a superconducting Electron Beam Ion Source, the Dresden EBIS-SC, under the aspect of application in combination with RCMS as a well proven technology. The measurements indicate that this ion source can offer significant advantages for medical particle therapy. We show that a superconducting EBIS can deliver ion pulses of medically relevant ions such as protons, C4 + and C6 + ions with intensities and frequencies required for RCMS [S. Peggs and T. Satogata, "A survey of Hadron therapy accelerator technology," in Proceedings of PAC07, BNL-79826- 2008-CP, Albuquerque, New Mexico, USA, 2007; A. Garonna, U. Amaldi et al., "Cyclinac medical accelerators using pulsed C6 +/H+_2 ion sources," in Proceedings of EBIST 2010, Stockholm, Sweden, July 2010]. Ion extraction spectra as well as individual ion pulses have been measured. For example, we report on the generation of proton pulses with up to 3 × 109 protons per pulse and with frequencies of up to 1000 Hz at electron beam currents of 600 mA.

  14. Design and Implementation of Adaptive Turbo Encoder for Quantized Software Defined Low-Power DVB-RCS Radios

    Directory of Open Access Journals (Sweden)

    S. H. Elramly

    2010-11-01

    Full Text Available Turbo codes are employed in every robust wireless digital communications system. Those codes have been adopted for the satellite return channel in DVB-RCS (Return Channel via Satellite standard. In Software Defined Radios (SDRs, Field Programmable Gate Array technology (FPGA is considered a highly configurable option for implementing many sophisticated signal processing tasks. The implementation for such codes is complex and dissipates a large amount of power. This paper studies the efficient implementation of quantized DVB-RCS turbo coding. Also, a low-power, turbo encoder for DVB-RCS is described using a VHDL code. The proposed encoder design is implemented on Xilinx Virtex-II Pro, XC2vpx30 FPGA chip. FPGA Advantage Pro package provided by Mentor Graphics is used for VHDL description and ISE 10.1 by Xilinx is used for synthetization.

  15. Moessbauer spectroscopy with synchrotron radiation

    International Nuclear Information System (INIS)

    Bergmann, U.

    1994-01-01

    The short pulse nature of synchrotron radiation makes it possible to perform Moessbauer spectroscopy in the time domain, i.e. instead of measuring the transmitted intensity time integrated as a function of source/absorber velocity, the intensity of the scattered radiation is measured time differential. The resulting time spectrum is essentially source independent and complications in the data analysis which are related to the radioactive source are completely removed. Furthermore, the large brightness and well defined polarization of the synchrotron radiation can, e.g., speed up the data collection and facilitate studies of polarization phenomena. To illustrate these new spectroscopic possibilities, measurements of the temperature dependence and polarization dependence of forward scattering from alpha - sup 5 sup 7 Fe nuclei are presented and discussed 26 refs., 5 figs. (author)

  16. Australian synchrotron light source - (boomerang)

    International Nuclear Information System (INIS)

    Boldeman, J.

    2001-01-01

    The Australian National Synchrotron Light Source - (Boomerang) is to be installed at the Monash University in Victoria. This report provides some background to the proposed facility and discusses aspects of a prospective design. Recently, significant effort was devoted to refining the in principle design and a lattice providing an emittance od 18 nm rad was obtained with a distributed dispersion in the straight section of 0.29m. Exhaustive studies have been made of the economic benefits that would accrue to Australia to Australia following the installation of this facility. This design is a refinement of the design concept presented to the SRI -2000, Berlin (Boldeman, Einfeld et al), to the meeting of the 4th Asian Forum and the Preliminary Design Study presented to the Australian Synchrotron Research Program

  17. Medical applications of synchrotron radiation

    International Nuclear Information System (INIS)

    Thomlinson, W.

    1992-01-01

    Ever since the first diagnostic X-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become incrasingly important. Both in clinical medicine and basic research the use of X-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved. (orig.)

  18. Synchrotron radiation in atomic physics

    International Nuclear Information System (INIS)

    Crasemann, B.

    1998-01-01

    Much of present understanding of atomic and molecular structure and dynamics was gained through studies of photon-atom interactions. In particular, observations of the emission, absorption, and scattering of X rays have complemented particle-collision experiments in elucidating the physics of atomic inner shells. Grounded on Max von Laue's theoretical insight and the invention of the Bragg spectrometer, the field's potential underwent a step function with the development of synchrotron-radiation sources. Notably current third-generation sources have opened new horizons in atomic and molecular physics by producing radiation of wide tunability and exceedingly high intensity and polarization, narrow energy bandwidth, and sharp time structure. In this review, recent advances in synchrotron-radiation studies in atomic and molecular science are outlined. Some tempting opportunities are surveyed that arise for future studies of atomic processes, including many-body effects, aspects of fundamental photon-atom interactions, and relativistic and quantum-electrodynamic phenomena. (author)

  19. Medical applications of synchrotron radiation

    International Nuclear Information System (INIS)

    Thomlinson, W.

    1991-10-01

    Ever since the first diagnostic x-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become increasingly important. Both in clinical medicine and basic research the use of x-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved

  20. Synchrotron X-radiation research

    International Nuclear Information System (INIS)

    Kabler, M.N.; Nagel, D.J.; Skelton, E.F.

    1990-05-01

    The Naval Research Laboratory (NRL) has been involved in the exploitation of X rays since the 1920s. The report gives a brief description of the generation and characteristics of synchrotron radiation, and review highlights of current research. Research examples include soft-X-ray optics, semiconductor surface passivation, surface electron dynamics, space-charge dynamics on silicon, photochemistry on GaAs, local atomic structure, crystal structures from X-ray diffraction. The report then discusses emerging research opportunities

  1. Threedimensional microfabrication using synchrotron radiation

    International Nuclear Information System (INIS)

    Ehrfeld, W.

    1990-01-01

    For fabricating microstructures with extreme structural heights a technology has been developed which is based on deep-etch lithography and subsequent replication processes. A particularly high precision is achieved if the lithographic process is carried out by means of synchrotron radiation. Electroforming and molding processes are used for the replication of microstructures from a large variety of materials. The field of application comprises sensors, electrical and optical microconnectors, components for fluid technology, microfiltration systems and novel composite materials. (author)

  2. Synchrotron/crystal sample preparation

    Science.gov (United States)

    Johnson, R. Barry

    1993-01-01

    The Center for Applied Optics (CAO) of the University of Alabama in Huntsville (UAH) prepared this final report entitled 'Synchrotron/Crystal Sample Preparation' in completion of contract NAS8-38609, Delivery Order No. 53. Hughes Danbury Optical Systems (HDOS) is manufacturing the Advanced X-ray Astrophysics Facility (AXAF) mirrors. These thin-walled, grazing incidence, Wolter Type-1 mirrors, varying in diameter from 1.2 to 0.68 meters, must be ground and polished using state-of-the-art techniques in order to prevent undue stress due to damage or the presence of crystals and inclusions. The effect of crystals on the polishing and grinding process must also be understood. This involves coating special samples of Zerodur and measuring the reflectivity of the coatings in a synchrotron system. In order to gain the understanding needed on the effect of the Zerodur crystals by the grinding and polishing process, UAH prepared glass samples by cutting, grinding, etching, and polishing as required to meet specifications for witness bars for synchrotron measurements and for investigations of crystals embedded in Zerodur. UAH then characterized these samples for subsurface damage and surface roughness and figure.

  3. Infrared microspectroscopy with synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Carr, G.L.; Williams, G.P. [Brookhaven National Lab., Upton, NY (United States). National Synchrotron Light Source

    1997-09-01

    Infrared microspectroscopy with a high brightness synchrotron source can achieve a spatial resolution approaching the diffraction limit. However, in order to realize this intrinsic source brightness at the specimen location, some care must be taken in designing the optical system. Also, when operating in diffraction limited conditions, the effective spatial resolution is no longer controlled by the apertures typically used for a conventional (geometrically defined) measurement. Instead, the spatial resolution depends on the wavelength of light and the effective apertures of the microscope`s Schwarzchild objectives. The authors have modeled the optical system from the synchrotron source up to the sample location and determined the diffraction-limited spatial distribution of light. Effects due to the dependence of the synchrotron source`s numerical aperture on wavelength, as well as the difference between transmission and reflection measurement modes, are also addressed. Lastly, they examine the benefits (when using a high brightness source) of an extrinsic germanium photoconductive detector with cone optics as a replacement for the standard MCT detector.

  4. Seabrook simulator model upgrade: Implementation and validation of two-phase, nonequilibrium RCS and steam generator models

    International Nuclear Information System (INIS)

    Kao, S.

    1990-01-01

    A number of deficiencies in the original RCS and steam generator models on the Seabrook simulator were found to give unrealistic results under some off-normal and accident conditions. These deficiencies are attributed to the simplistic assumptions used in the original models, such as the homogeneous, equilibrium equations used in the pressurizer and steam generator models, and the single-phase flow model used in the RCS thermal-hydraulic model. To improve the fidelity of the simulator, efforts have been made to upgrade the RCS and steam generator models to include two-phase, nonequilibrium features. In the new RCS model, the following major assumptions are used to derive the finite difference form of the conservation equations: a donor-cell differencing scheme is adopted to allow flow reversal; a single pressure is used to evaluate properties; a single mass flow rate is assumed in each loop; enthalpy is assumed to vary linearly within each control volume; a homogeneous flow is assumed under two-phase conditions. The pressurizer is divided into a vapor region and a liquid region, each of which is represented by a set of mass and energy conservation equations. Interfacial mass and energy exchange mechanisms (condensation and flashing), thermal interactions between the vessel and fluids, and thermal nonequilibrium between the phases are included in the pressurizer model. The steam generator is divided into the vapor dome, riser, and downcomer regions. The assumptions applied are similar to those of the RCS and pressurizer models. A momentum model is incorporated to calculate the recirculation flow and simulate the downcomer level shrink/swell phenomenon. The new RCS and steam generator models are validated by comparing the simulator calculations against sister plant data and FSAR vendor analysis. The results show the new models give realistic and reliable calculations under off-normal and accident conditions

  5. Localization and Developmental Expression Patterns of CSPG in the RCS Rat Retina

    Directory of Open Access Journals (Sweden)

    Li-Feng Chen

    2011-05-01

    Full Text Available Purpose: Investigate changes in chondroitin sulfate proteoglycan (CSPG distribution in Royal College of Surgeons (RCS rat retinae. Could CSPGs distribution act as a physical barrier to transplanted cell migration in degenerating retinae? Methods: CSPG expression was examined in RCS and Long-Evans rat retinae from birth to postnatal day 150 (PND150 using immunofluorescence and western-blots. Results: Both groups showed a rapid rise in CSPG expression on PND14, which peaked on PND21 before declining to lower levels by PND35. CSPG expression had risen again by PND90 and remained elevated for the duration of the study (PND150. However, from PND21, CSPG expression was significantly higher (p ≤ 0.05, n = 5 in Long-Evans rat retinae. CSPG-positive cells were localized in the ganglion cell layer (GCL and the photoreceptor outer segment debris zone (DZ; CSPG expression in the DZ was the main contributor to the higher expression in older animals for both groups. Conclusions: Increased expression of CSPGs in the DZ may act as a physical barrier following retinal cellular transplantation. CSPGs in the GCL is probably related to dendritic changes. CSPG accumulation in the older retinae suggests that aging influences the microenvironment in the retina, which may affect the efficacy of cell transplantation.

  6. In situ degassing of the kicker magnet in J-PARC RCS

    International Nuclear Information System (INIS)

    Kamiya, Junichiro; Ogiwara, Norio; Hikichi, Yusuke; Yanagibashi, Toru; Kinsho, Michikazu

    2015-01-01

    The usual way to reduce outgassing from a device in vacuum is to heat up a whole vacuum chamber containing the device. However, the situation, where this method can be applied, is limited due to the heat expansion of the chamber. Especially in accelerators, where the vacuum chambers are connected with nearby beam pipes, this normal bake-out method may not be applied. If a heat source and heat shields are appropriately installed inside the chamber, heat flux is directed to the device. Therefore the device can be baked out without raising the temperature of the vacuum chamber. One candidate for such bake-out method to be applied is kicker magnets in J-PARC RCS, which are installed in large vacuum chambers. We performed the heating tests with some types of heaters in order to examine the effectiveness of this method and to decide the material and configuration of the heater. As a result, the graphite heater was selected for in-situ bake-out of the kickers in the RCS beam line. Using the method, the each material of kicker magnet was heated up above 100degC with keeping the temperature rise of the vacuum chamber below 30degC. (author)

  7. Reduction of the In-Band RCS of Microstrip Patch Antenna by Using Offset Feeding Technique

    Directory of Open Access Journals (Sweden)

    Weiwei Xu

    2014-01-01

    Full Text Available This paper presents a method for implementing a low in-band scattering design for microstrip patch antennas based on the analysis of structural mode scattering and radiation characteristics. The antenna structure is first designed to have the lowest structural mode scattering in a desired frequency band. The operating frequency band of the antenna is then changed to coincide with that of the lowest structural mode scattering by adjusting the feed position on the antenna (offset feeding to achieve an antenna with low in-band radar cross section (RCS. In order to reduce the level of cross polarization of the antenna caused by offset feeding, symmetry feeding structures for both single patch antennas and two-patch arrays are proposed. Examples that show the efficiency of the method are given, and the results illustrate that the in-band RCS of the proposed antennas can be reduced by as much as 17 dBsm for plane waves impinging from the normal direction compared to patch antennas fed by conventional methods.

  8. Error Analysis of Relative Calibration for RCS Measurement on Ground Plane Range

    Directory of Open Access Journals (Sweden)

    Wu Peng-fei

    2012-03-01

    Full Text Available Ground plane range is a kind of outdoor Radar Cross Section (RCS test range used for static measurement of full-size or scaled targets. Starting from the characteristics of ground plane range, the impact of environments on targets and calibrators is analyzed during calibration in the RCS measurements. The error of relative calibration produced by the different illumination of target and calibrator is studied. The relative calibration technique used in ground plane range is to place the calibrator on a fixed and auxiliary pylon somewhere between the radar and the target under test. By considering the effect of ground reflection and antenna pattern, the relationship between the magnitude of echoes and the position of calibrator is discussed. According to the different distances between the calibrator and target, the difference between free space and ground plane range is studied and the error of relative calibration is calculated. Numerical simulation results are presented with useful conclusions. The relative calibration error varies with the position of calibrator, frequency and antenna beam width. In most case, set calibrator close to the target may keep the error under control.

  9. Loss of calretinin immunoreactive fibers in subcortical visual recipient structures of the RCS dystrophic rat.

    Science.gov (United States)

    Vugler, Anthony A; Coffey, Peter J

    2003-11-01

    The retinae of dystrophic Royal College of Surgeons (RCS) rats exhibit progressive photoreceptor degeneration accompanied by pathology of ganglion cells. To date, little work has examined the consequences of retinal degeneration for central visual structures in dystrophic rats. Here, we use immunohistochemistry for calretinin (CR) to label retinal afferents in the superior colliculus (SC), lateral geniculate nucleus, and olivary pretectal nucleus of RCS rats aged between 2 and 26 months of age. Early indications of fiber loss in the medial dystrophic SC were apparent between 9 and 13 months. Quantitative methods reveal a significant reduction in the level of CR immunoreactivity in visual layers of the medial dystrophic SC at 13 months (P animals aged 19-26 months the loss of CR fibers in SC was dramatic, with well-defined patches of fiber degeneration predominating in medial aspects of the structure. This fiber degeneration in SC was accompanied by increased detection of cells immunoreactive for CR. In several animals, regions of fiber loss were also found to contain strongly parvalbumin-immunoreactive cells. Loss of CR fibers was also observed in the lateral geniculate nucleus and olivary pretectal nucleus. Patterns of fiber loss in the dystrophic SC compliment reports of ganglion cell degeneration in these animals and the response of collicular neurons to degeneration is discussed in terms of plasticity of the dystrophic visual system and properties of calcium binding proteins.

  10. National demonstration of full reactor coolant system (RCS) chemical decontamination at Indian Point 2

    Energy Technology Data Exchange (ETDEWEB)

    Trovato, S.A.; Parry, J.O. [Consolidated Edison Co., New York, NY (United States)

    1995-03-01

    Key to the safe and efficient operation of the nation`s civilian nuclear power plants is the performance of maintenance activities within regulations and guidelines for personnel radiation exposure. However, maintenance activities, often performed in areas of relatively high radiation fields, will increase as the nation`s plant age. With the Nuclear Regulatory Commission (NRC) lowering the allowable radiation exposure to plant workers in 1994 and considering further reductions and regulations in the future, it is imperative that new techniques be developed and applied to reduce personnel exposure. Full primary system chemical decontamination technology offers the potential to be single most effective method of maintaining workers exposure {open_quotes}as low as reasonably achievable{close_quotes} (ALARA) while greatly reducing plant operation and maintenance (O&M) costs. A three-phase program underway since 1987, has as its goal to demonstrate that full RCS decontamination is a visible technology to reduce general plant radiation levels without threatening the long term reliability and operability of a plant. This paper discusses research leading to and plans for a National Demonstration of Full RCS Chemical Decontamination at Indian Point 2 nuclear generating station in 1995.

  11. Possible sources of neuroprotection following subretinal silicon chip implantation in RCS rats

    Science.gov (United States)

    Pardue, Machelle T.; Phillips, Michael J.; Yin, Hang; Fernandes, Alcides; Cheng, Yian; Chow, Alan Y.; Ball, Sherry L.

    2005-03-01

    Current retinal prosthetics are designed to stimulate existing neural circuits in diseased retinas to create a visual signal. However, implantation of retinal prosthetics may create a neurotrophic environment that also leads to improvements in visual function. Possible sources of increased neuroprotective effects on the retina may arise from electrical activity generated by the prosthetic, mechanical injury due to surgical implantation, and/or presence of a chronic foreign body. This study evaluates these three neuroprotective sources by implanting Royal College of Surgeons (RCS) rats, a model of retinitis pigmentosa, with a subretinal implant at an early stage of photoreceptor degeneration. Treatment groups included rats implanted with active and inactive devices, as well as sham-operated. These groups were compared to unoperated controls. Evaluation of retinal function throughout an 18 week post-implantation period demonstrated transient functional improvements in eyes implanted with an inactive device at 6, 12 and 14 weeks post-implantation. However, the number of photoreceptors located directly over or around the implant or sham incision was significantly increased in eyes implanted with an active or inactive device or sham-operated. These results indicate that in the RCS rat localized neuroprotection of photoreceptors from mechanical injury or a chronic foreign body may provide similar results to subretinal electrical stimulation at the current output evaluated here.

  12. THYDE-P2 code: RCS (reactor-coolant system) analysis code

    International Nuclear Information System (INIS)

    Asahi, Yoshiro; Hirano, Masashi; Sato, Kazuo

    1986-12-01

    THYDE-P2, being characterized by the new thermal-hydraulic network model, is applicable to analysis of RCS behaviors in response to various disturbances including LB (large break)-LOCA(loss-of-coolant accident). In LB-LOCA analysis, THYDE-P2 is capable of through calculation from its initiation to complete reflooding of the core without an artificial change in the methods and models. The first half of the report is the description of the methods and models for use in the THYDE-P2 code, i.e., (1) the thermal-hydraulic network model, (2) the various RCS components models, (3) the heat sources in fuel, (4) the heat transfer correlations, (5) the mechanical behavior of clad and fuel, and (6) the steady state adjustment. The second half of the report is the user's mannual for the THYDE-P2 code (version SV04L08A) containing items; (1) the program control (2) the input requirements, (3) the execution of THYDE-P2 job, (4) the output specifications and (5) the sample problem to demonstrate capability of the thermal-hydraulic network model, among other things. (author)

  13. Synchrotron Environmental Science-I Workshop Report

    International Nuclear Information System (INIS)

    1999-01-01

    Attendees of the Synchrotrons Environmental Science 1 (SES-1) workshop represented a broad spectrum of environmental science research areas and expertise in all of the current synchrotrons techniques (X-ray scattering and diffraction, X-ray absorption spectroscopy, and two- and three-dimensional X-ray imaging). These individuals came together to discuss current measurement obstacles in environmental research and, more specifically, ways to overcome such obstacles by applying synchrotrons radiation techniques. Significant obstacles in measurement affect virtually all of the research issues described. Attendees identified synchrotrons approaches of potential value in their research. A number of the environmental research studies discussed are currently being addressed with some success by synchrotron-based approaches. Nevertheless, improvements in low-Z measurement capabilities are needed to facilitate the use of synchrotrons radiation methodologies in environmental research

  14. Synchrotron Environmental Science-I Workshop Report.

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-08

    Attendees of the Synchrotrons Environmental Science 1 (SES-1) workshop represented a broad spectrum of environmental science research areas and expertise in all of the current synchrotrons techniques (X-ray scattering and diffraction, X-ray absorption spectroscopy, and two- and three-dimensional X-ray imaging). These individuals came together to discuss current measurement obstacles in environmental research and, more specifically, ways to overcome such obstacles by applying synchrotrons radiation techniques. Significant obstacles in measurement affect virtually all of the research issues described. Attendees identified synchrotrons approaches of potential value in their research. A number of the environmental research studies discussed are currently being addressed with some success by synchrotron-based approaches. Nevertheless, improvements in low-Z measurement capabilities are needed to facilitate the use of synchrotrons radiation methodologies in environmental research.

  15. Light source for synchrotron radiation x-ray topography study at Beijing Synchrotron Radiation Laboratory (BSRL)

    International Nuclear Information System (INIS)

    Zhao Jiyong; Jiang Jianhua; Tian Yulian

    1992-01-01

    Characteristics of the synchrotron radiation source for X-ray topography study at Beijing Synchrotron Radiation Laboratory (BSRL) is described, local geometrical resolution of topographies is discussed, and the diffracting intensities of white beam topography is given

  16. Support for Synchrotron Access by Environmental Scientists

    International Nuclear Information System (INIS)

    Daly, Michael; Madden, Andrew; Palumbo, Anthony; Qafoku, N.

    2006-01-01

    To support ERSP-funded scientists in all aspects of synchrotron-based research at the Advanced Photon Source (APS). This support comes in one or more of the following forms: (1) writing proposals to the APS General User (GU) program, (2) providing time at MRCAT/EnviroCAT beamlines via the membership of the Molecular Environmental Science (MES) Group in MRCAT/EnviroCAT, (3) assistance in experimental design and sample preparation, (4) support at the beamline during the synchrotron experiment, (5) analysis and interpretation of the synchrotron data, and (6) integration of synchrotron experimental results into manuscripts

  17. Atomic physics research with synchrotron radiation

    International Nuclear Information System (INIS)

    Crasemann, B.; Wuilleumier, F.

    1985-01-01

    This chapter discusses applications of synchrotron light in atomic and molecular physics. Use of the radiation from storage rings has expanded and lent access to new areas of absorption and photoemission spectroscopy and scattering experiments. Techniques applied in connection with synchrotron radiation are discussed including absorption spectroscopy, photoelectron spectroscopy, fluorescence spectroscopy and X-ray scattering. Problem areas that are being studied by the techniques mentioned above are discussed. Synchrotron radiation has provided the means for measuring the threshold-excitation and interference effects that signal the breakdown of the two-step model of atomic excitation/deexcitation. Synchrotron radiation provides more means of excited-state photoionization measurements

  18. Synchrotron Radiation in Biology and Medicine

    International Nuclear Information System (INIS)

    Pelka, J.B.

    2008-01-01

    This work is focused on a present status of synchrotron radiation X-ray applications in medicine and biology to imaging, diagnostics, and radio- therapy. Properties of X-ray beams generated by synchrotron sources are compared with radiation produced by classical laboratory X-ray tubes. A list of operating and planned synchrotron facilities applicable to biomedical purposes is given, together with their basic characteristics. A concise overview of typical X-ray synchrotron techniques in biology and medicine is carried out with discussion of their specific properties and examples of typical results. (author)

  19. The Stanford Synchrotron Radiation Laboratory, 20 years of synchrotron light

    International Nuclear Information System (INIS)

    Cantwell, K.

    1993-08-01

    The Stanford Synchrotron Radiation Laboratory (SSRL) is now operating as a fully dedicated light source with low emittance electron optics, delivering high brightness photon beams to 25 experimental stations six to seven months per year. On October 1, 1993 SSRL became a Division of the Stanford Linear Accelerator Center, rather than an Independent Laboratory of Stanford University, so that high energy physics and synchrotron radiation now function under a single DOE contract. The SSRL division of SLAC has responsibility for operating, maintaining and improving the SPEAR accelerator complex, which includes the storage ring and a 3 GeV injector. SSRL has thirteen x-ray stations and twelve VUV/Soft x-ray stations serving its 600 users. Recently opened to users is a new spherical grating monochromator (SGM) and a multiundulator beam line. Circularly polarized capabilities are being exploited on a second SGM line. New YB 66 crystals installed in a vacuum double-crystal monochromator line have sparked new interest for Al and Mg edge studies. One of the most heavily subscribed stations is the rotation camera, which has been recently enhanced with a MAR imaging plate detector system for protein crystallography on a multipole wiggler. Under construction is a new wiggler-based structural molecular biology beam line with experimental stations for crystallography, small angle scattering and x-ray absorption spectroscopy. Plans for new developments include wiggler beam lines and associated facilities specialized for environmental research and materials processing

  20. Sensitivities in synchrotron radiation TXRF

    International Nuclear Information System (INIS)

    Pianetta, P.; Baur, K.; Brennan, S.

    2000-01-01

    This work describes the progress we achieved at the Stanford Synchrotron Radiation Laboratory (SSRL) in improving the sensitivity for both the transition metals and light elements such as Al and Na. The transition metal work has matured to the point where a facility exists at SSRL in which semiconductor companies are able to perform industrially relevant measurements at state of the art detection limits. This facility features clean wafer handling and automated data acquisition making routine analytical measurements possible. The best sensitivity demonstrated so far is 3.4 E7 atoms/cm 2 for a 5000 second count time corresponding to 7.6 E7 atoms/cm 2 for a standard 1000 second count time. This is more than a factor of 100 better than what can be achieved with conventional TXRF systems. The detection of light elements such as Al and Na is challenging due to the presence of the h stronger Si fluorescence peak. For traditional energy-dispersive detection only the tunability of synchrotron radiation to excitation energies below the Si-K absorption edge leads to an acceptable sensitivity for Al detection which is limited by a large background due to inelastic x-ray Raman scattering. An alternative approach to overcome the Raman contribution and the strong Si fluorescence is to use a wavelength-dispersive spectrometer for fluorescence detection. The benefits of such a multilayer spectrometer over a solid state detector are its higher energy resolution and greater dynamic range. This strategy allows primary excitation above the Si K absorption edge, eliminating the background due to Raman scattering, and a gracing emission geometry to guarantee high surface sensitivity. Studies testing this concept in combination with high flux synchrotron radiation are underway and first results will be presented. (author)

  1. Synchrotron light and its uses

    International Nuclear Information System (INIS)

    Blewett, J.P.

    1978-01-01

    It was known for a century that charged particles radiate when accelerated and that relativistic electrons in the energy range between 100 MeV and several GeV and constrained to travel in circular orbits emit concentrated, intense beams with broad continuous spectra that can cover the electromagnetic spectrum from infrared through hard x-rays. Recently the possible applications of this radiation were appreciated and electron synchrotrons and electron storage rings are now being used in many centers for studies of the properties of matter in the solid, liquid and gaseous states. 10 references

  2. Vacuum system for HIMAC synchrotrons

    International Nuclear Information System (INIS)

    Kanazawa, M.; Sudou, M.; Sato, K.

    1994-01-01

    HIMAC synchrotrons are now under construction, which require vacuum chambers of large aperture and high vacuum of about 10 -9 torr. Wide thin wall vacuum chamber of 0.3 mm thickness reinforced with ribs has been developed as the chamber at dipole magnet. We have just now started to evacuate the lower ring. The obtained average value was about 5x10 -8 torr with turbo-molecular and sputter ion pumps, and 1.1x10 -9 torr after baking. (author)

  3. Barrier rf systems in synchrotrons

    International Nuclear Information System (INIS)

    Bhat, Chandra M.

    2004-01-01

    Recently, many interesting applications of the barrier RF system in hadron synchrotrons have been realized. A remarkable example of this is the development of longitudinal momentum mining and implementation at the Fermilab Recycler for extraction of low emittance pbars for the Tevatron shots. At Fermilab, we have barrier RF systems in four different rings. In the case of Recycler Ring, all of the rf manipulations are carried out using a barrier RF system. Here, the author reviews various uses of barrier rf systems in particle accelerators including some new schemes for producing intense proton beam and possible new applications

  4. Longitudinal tune control in synchrotrons

    International Nuclear Information System (INIS)

    Colton, E.P.

    1984-01-01

    Dual rf systems that use fundamental and higher-harmonic cavities can be used to control the longitudinal tune in synchrotrons. The equations of motion and the Hamiltonian are defined for particle motion using dual rf systems. An example is considered using a second-harmonic system - it is shown, that as phi/sub s/ is increased, a substantial gain in bucket area over a single rf system can be realized by proper relative phasing of the first- and second-harmonic voltages

  5. Synchrotron radiation and fusion materials

    International Nuclear Information System (INIS)

    Nielsen, S.F.

    2009-01-01

    The development of fusion energy is approaching a stage where the capabilities of materials will be dictating the further progress and the time scale for the attainment of fusion power. EU has therefore funded the Fusion Energy Materials Science project Coordination Action (FEMaS - CA) with the intension to utilise the know-how in the materials community to help overcome the material science problems with the fusion related materials. The FEMaS project and some of the possible applications of synchrotron radiation for materials characterisation are described in this paper. (au)

  6. Accumulation of neurocan, a brain chondroitin sulfate proteoglycan, in association with the retinal vasculature in RCS rats.

    Science.gov (United States)

    Zhang, Yiqin; Rauch, Uwe; Perez, Maria-Thereza R

    2003-03-01

    To examine whether and how the retinal distribution of the chondroitin sulfate proteoglycan neurocan is affected after photoreceptor cell loss and whether it correlates with the multiple secondary cellular changes that accompany the photoreceptor degeneration. Retinas from normal rats (Sprague-Dawley; postnatal days [P]0-P70), RCS rats with dystrophic retinas (P0-P300), RCS-rdy(+) congenic rats with nondystrophic retinas (P0-202), and rhodopsin mutant rats, P23H (P0-P257) and S334ter (P0-P220), were processed for immunohistochemistry using a polyclonal antibody to rat neurocan. The overall distribution of neurocan was similar in all retinas examined. Neurocan immunostaining was detected over the nerve fiber layer, the plexiform layers, the photoreceptor outer segments region, and the ciliary epithelium. With age, labeling throughout the plexiform layers decreased continuously. In RCS rats however, conspicuous labeling was also seen in association with retinal vessels, from P15 onward. Accumulation of neurocan in association with the retinal vasculature does not correlate with photoreceptor cell loss, because it was not observed in the rhodopsin mutant rats. During the earliest stages of the disease, accumulation of debris in the subretinal space in RCS rats may be sufficient per se to initiate a cascade of metabolic changes that result in accumulation of neurocan. With time, the neurocan accumulated perivascularly may, by interaction with other matrix molecules, modulate at least some of the vascular alterations observed in this animal model.

  7. STS-46 Atlantis', OV-104's, vertical tail and OMS pods lit up by RCS jet firing

    Science.gov (United States)

    1992-01-01

    STS-46 Atlantis', Orbiter Vehicle (OV) 104's, vertical tail and orbital maneuvering system (OMS) pods are highlighted by the glow of the reaction control system (RCS) jet firings. OV-104 was at an altitude of 128 nautical miles. The remote manipulator system (RMS) arm is partially visible stowed along the port side sill longeron.

  8. Malignant mast cell tumor of the thymus in an Royal College of Surgeons (RCS) rat.

    Science.gov (United States)

    Terayama, Yui; Matsuura, Tetsuro; Ozaki, Kiyokazu

    2017-01-01

    A 152-week-old male Royal College of Surgeons (RCS) rat kept as a non-treated animal in a long-term animal study presented with a soft mass in the anterior mediastinum, which adhered to the pleura of the lung. Histopathologically, the mass mainly consisted of round to short spindle-shaped tumor cells that had infiltrated through the hyperplastic thymic tissue. The tumor cells were arranged in loose to dense sheets. Nuclei were moderate in size and round to spindle-shaped, with small nucleoli. Almost all tumor cells exhibited abundant eosinophilic cytoplasm, including eosinophilic granules of a range of sizes. The granules of tumor cells exhibited metachromasia with toluidine blue stain and were positive for c-kit and mast cell protease II. These findings indicate that the tumor described here represents a rare case of spontaneous malignant mast cell tumor with thymic epithelial hyperplasia.

  9. The third generation French synchrotron

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    This short paper gives a concise presentation of the SOLEIL project of the LURE synchrotron radiation national laboratory at Orsay (France). This new accelerator is devoted to replace the DCI and Super ACO rings of first and second generation, respectively. The main research domains of this project concern: the micro-fluorescence and micro-diffraction characterization of materials, and in particular the electronic components; the study of matter in extreme conditions (high temperature and high pressure); the bio-crystallography; the study of aggregates; and the manufacturing of micro-instruments for micro-electronics or medical applications. SOLEIL will be equipped with special magnetic wigglers to obtain very high brightness sources. The source will be a 336 m circumference ring for 2.5 GeV electron storage, able to produce a large spectrum synchrotron radiation. The injection system will comprise a low energy-high current linear electron accelerator and two electron beam transport lines. The installation will be buried at a 4 m depth to ensure the environmental protection and to limit vibrations. (J.S.)

  10. Photoemission spectroscopy using synchrotron radiation

    International Nuclear Information System (INIS)

    Kobayashi, K.L.I.

    1980-01-01

    It is an epoch making event for photoemission spectroscopy that the light sources of continuous wavelength from vacuum ultra-violet to X-ray region have become available by the advent of synchrotron radiation. Specifically the progress after stable intense light has become obtainable from storage rings is very significant. One of the features of these synchrotron radiation is its extreme polarization of radiating pattern. Though the elementary processes of photoemission out of solids are the basic themes, phenomenalistic 3-stage model is usually applied to the analysis of experiments. In this model, the process of photoemission is considered by dividing into three stages, namely the generation of photoelectrons due to optical transition between electron status -- the transportation of photoelectrons to solid surfaces -- breaking away from the surfaces. The spectrometers, the energy analyzers of photoelectrons, and sample-preparing room used for photoemission spectroscopy are described. Next, energy distribution curves are explained. At the end, photoelectron yield spectroscopy, CFS (constant final energy spectroscopy) and CIS (constant initial energy spectroscopy), Auger yield and interatomic Auger yield, the determination of surface structure by normal emission CIS, and surface EXAFS (extended X-ray absorption fine structure) are described. As seen above, the application specifically to surface physics is promising in the future. (Wakatsuki, Y.)

  11. Synchrotron-driven spallation sources

    CERN Document Server

    Bryant, P J

    1996-01-01

    The use of synchrotrons for pulsed neutron spallation sources is an example of scientific and technological spin-off from the accelerator development for particle physics. Accelerator-driven sources provide an alternative to the continuous-flux, nuclear reactors that currently furnish the majority of neutrons for research and development. Although the present demand for neutrons can be adequately met by the existing reactors, this situation is unlikely to continue due to the increasing severity of safety regulations and the declared policies of many countries to close down their reactors within the next decade or so. Since the demand for neutrons as a research tool is, in any case,expected to grow, there has been a corresponding interest in sources that are synchrotron-driven or linac-driven with a pulse compression ring and currently several design studies are being made. These accelerator-driven sources also have the advantage of a time structure with a high peak neutron flux. The basic requirement is for a...

  12. Sirepo for Synchrotron Radiation Workshop

    Energy Technology Data Exchange (ETDEWEB)

    2016-10-25

    Sirepo is an open source framework for cloud computing. The graphical user interface (GUI) for Sirepo, also known as the client, executes in any HTML5 compliant web browser on any computing platform, including tablets. The client is built in JavaScript, making use of the following open source libraries: Bootstrap, which is fundamental for cross-platform web applications; AngularJS, which provides a model–view–controller (MVC) architecture and GUI components; and D3.js, which provides interactive plots and data-driven transformations. The Sirepo server is built on the following Python technologies: Flask, which is a lightweight framework for web development; Jinja, which is a secure and widely used templating language; and Werkzeug, a utility library that is compliant with the WSGI standard. We use Nginx as the HTTP server and proxy, which provides a scalable event-driven architecture. The physics codes supported by Sirepo execute inside a Docker container. One of the codes supported by Sirepo is the Synchrotron Radiation Workshop (SRW). SRW computes synchrotron radiation from relativistic electrons in arbitrary magnetic fields and propagates the radiation wavefronts through optical beamlines. SRW is open source and is primarily supported by Dr. Oleg Chubar of NSLS-II at Brookhaven National Laboratory.

  13. High pressure and synchrotron radiation satellite workshop

    Energy Technology Data Exchange (ETDEWEB)

    Bass, J.; Guignot, N.; Morard, G.; Mezouar, M.; Andrault, D.; Bolfan-Casanova, N.; Sturhahn, W.; Daniel, I.; Reynard, B.; Simionovici, A.; Sanchez Valle, C.; Martinez, I.; Kantor, I.; Dubrovinsky, I.; Mccammon, C.; Dubrovinskaia, N.; Kurnosiv, A.; Kuznetsov, A.; Goncharenko, I.; Loubeyre, P.; Desgreniers, S.; Weck, G.; Yoo, C.S.; Iota, V.; Park, J.; Cynn, H.; Gorelli, F.; Toulemonde, P.; Machon, D.; Merlen, A.; San Miguel, A.; Amboage, M.; Aquilanti, G.; Mathon, O.; Pascarelli, S.; Itie, J.P.; Mcmillan, P.F.; Trapananti, A.; Di Cicco, A.; Panfilis, S. de; Filipponi, A.; Kreisel, J.; Bouvier, P.; Dkhil, B.; Chaabane, B.; Rosner, H.; Koudela, D.; Schwarz, U.; Handestein, A.; Hanfland, M.; Opahle, I.; Koepernik, K.; Kuzmin, M.; Mueller, K.H.; Mydosh, J.; Richter, M.; Hejny, C.; Falconi, S.; Lundegaard, L.F.; Mcmahon, M.I; Loa, I.; Syassen, K.; Wang, X.; Roth, H.; Lorenz, T.; Farber Daniel, I.; Antonangeli Daniele, I.; Krisch, M.; Badro, J.; Fiquet, G.; Occelli, F.; Mao, W.L.; Mao, H.K.; Eng, P.; Kao, C.C.; Shu, J.F.; Hemley, R.J.; Tse, J.S.; Yao, Y.; Deen, P.P.; Paolasini, I.; Braithwaite, D.; Kernavanois, N.; Lapertot, G.; Rupprecht, K.; Leupold, O.; Ponkratz, U.; Wortmann, G.; Beraud, A.; Krisch, M.; Farber, D.; Antonangeli, D.; Aracne, C.; Zarestky, J.L.; Mcqueeney, R.; Mathon, O.; Baudelet, F.; Decremps, F.; Itie, J.P.; Nataf, I.; Pascarelli, S.; Polian, A

    2006-07-01

    The workshop is dedicated to recent advances on science at high pressure at third generation synchrotron sources. A variety of experiments using synchrotron radiation techniques including X-ray diffraction, EXAFS (extended X-ray absorption fine structure), inelastic X-ray scattering, Compton scattering and Moessbauer spectroscopy of crystalline, liquid or amorphous samples, are reported. This document gathers the abstracts of the presentations.

  14. Synchrotron applications in wood preservation and deterioration

    Science.gov (United States)

    Barbara L. Illman

    2003-01-01

    Several non-intrusive synchrotron techniques are being used to detect and study wood decay. The techniques use high intensity synchrotron-generated X-rays to determine the atomic structure of materials with imaging, diffraction, and absorption. Some of the techniques are X-ray absorption near edge structure (XANES), X-ray fluorescence spectroscopy (XFS), X-ray...

  15. The Synchrotron Radiation Facility ESFR in Grenoble

    International Nuclear Information System (INIS)

    Haensel, R.

    1994-01-01

    The European Synchrotron Radiation Facility (ESFR) is the first synchrotron radiation source of the 3-th generation for Roentgen radiations.It permits a new series of experiments in the domains of physics, chemistry, materials studies, micromechanics, biology, medicine and crystallography. The main part of device represents the 850 meter storage ring of 6 GeV electrons. (MSA)

  16. Current status of Hiroshima Synchrotron Radiation Center

    International Nuclear Information System (INIS)

    Taniguchi, Masaki

    2000-01-01

    The Hiroshima Synchrotron Radiation Center is a common facility for both research and education in the field of synchrotron radiation science. The role of the center is to promote original research, training of young scientists, international exchange and cooperative research with neighbouring universities, public organizations and industries. (author)

  17. Infrared spectroscopy by use of synchrotron radiation

    International Nuclear Information System (INIS)

    Nanba, Takao

    1991-01-01

    During five years since the author wrote the paper on the utilization of synchrotron radiation in long wavelength region, it seems to be recognized that in synchrotron radiation, the light from infrared to milli wave can be utilized, and is considerably useful. Recently the research on coherent synchrotron radiation in this region using electron linac has been developed by Tohoku University group, and the high capability of synchrotron radiation as light source is verified. This paper is the report on the infrared spectroscopic research using incoherent synchrotron radiation obtained from the deflection electromagnet part of electron storage rings. Synchrotron radiation is high luminance white light source including from X-ray to micro wave. The example of research that the author carried out at UVSOR is reported, and the perspective in near future is mentioned. Synchrotron radiation as the light source for infrared spectroscopy, the intensity and dimensions of the light source, far infrared region and mid infrared region, far infrared high pressure spectroscopic experiment, and the heightening of luminance of synchrotron radiation as infrared light source are described. (K.I.)

  18. High pressure and synchrotron radiation satellite workshop

    International Nuclear Information System (INIS)

    Bass, J.; Guignot, N.; Morard, G.; Mezouar, M.; Andrault, D.; Bolfan-Casanova, N.; Sturhahn, W.; Daniel, I.; Reynard, B.; Simionovici, A.; Sanchez Valle, C.; Martinez, I.; Kantor, I.; Dubrovinsky, I.; Mccammon, C.; Dubrovinskaia, N.; Kurnosiv, A.; Kuznetsov, A.; Goncharenko, I.; Loubeyre, P.; Desgreniers, S.; Weck, G.; Yoo, C.S.; Iota, V.; Park, J.; Cynn, H.; Gorelli, F.; Toulemonde, P.; Machon, D.; Merlen, A.; San Miguel, A.; Amboage, M.; Aquilanti, G.; Mathon, O.; Pascarelli, S.; Itie, J.P.; Mcmillan, P.F.; Trapananti, A.; Di Cicco, A.; Panfilis, S. de; Filipponi, A.; Kreisel, J.; Bouvier, P.; Dkhil, B.; Chaabane, B.; Rosner, H.; Koudela, D.; Schwarz, U.; Handestein, A.; Hanfland, M.; Opahle, I.; Koepernik, K.; Kuzmin, M.; Mueller, K.H.; Mydosh, J.; Richter, M.; Hejny, C.; Falconi, S.; Lundegaard, L.F.; Mcmahon, M.I; Loa, I.; Syassen, K.; Wang, X.; Roth, H.; Lorenz, T.; Farber Daniel, I.; Antonangeli Daniele, I.; Krisch, M.; Badro, J.; Fiquet, G.; Occelli, F.; Mao, W.L.; Mao, H.K.; Eng, P.; Kao, C.C.; Shu, J.F.; Hemley, R.J.; Tse, J.S.; Yao, Y.; Deen, P.P.; Paolasini, I.; Braithwaite, D.; Kernavanois, N.; Lapertot, G.; Rupprecht, K.; Leupold, O.; Ponkratz, U.; Wortmann, G.; Beraud, A.; Krisch, M.; Farber, D.; Antonangeli, D.; Aracne, C.; Zarestky, J.L.; Mcqueeney, R.; Mathon, O.; Baudelet, F.; Decremps, F.; Itie, J.P.; Nataf, I.; Pascarelli, S.; Polian, A.

    2006-01-01

    The workshop is dedicated to recent advances on science at high pressure at third generation synchrotron sources. A variety of experiments using synchrotron radiation techniques including X-ray diffraction, EXAFS (extended X-ray absorption fine structure), inelastic X-ray scattering, Compton scattering and Moessbauer spectroscopy of crystalline, liquid or amorphous samples, are reported. This document gathers the abstracts of the presentations

  19. Funding problems threaten Middle East's synchrotron

    CERN Multimedia

    McCabe, H

    1999-01-01

    Scientists will tour the Middle East to try to raise support for the Synchrotron radiation for Experimental Science and Applications in the Middle East project. The plan is to dismantle and move a decommissioned synchrotron from Berlin to the Middle East where scientists of any nationality would be able to use it (3 paragraphs).

  20. Medical applications with synchrotron radiation in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, T.; Itai, Y. [Univ. of Tsukuba, Inst. of Clinical Medicine, Tsukuba (Japan); Hyodo, K.; Ando, M. [KEK, Tsukuba (Japan); Akatsuka, T. [Yamagata Univ., Faculty of Engineering, Yamagata (Japan); Uyama, C. [National Cardiovascular Centre, Suita (Japan)

    1998-05-01

    In Japan, various medical applications of synchrotron X-ray imaging, such as angiography, monochromatic X-ray computed tomography (CT), radiography and radiation therapy, are being developed. In particular, coronary arteriography (CAG) is quite an important clinical application of synchrotron radiation. Using a two-dimensional imaging method, the first human intravenous CAG was carried out at KEK in May 1996; however, further improvements of image quality are required in clinical practice. On the other hand, two-dimensional aortographic CAG revealed canine coronary arteries as clearly as those on selective CAG, and coronary arteries less than 0.2 mm in diameter. Among applications of synchrotron radiation to X-ray CT, phase-contrast X-ray CT and fluorescent X-ray CT are expected to be very interesting future applications of synchrotron radiation. For actual clinical applications of synchrotron radiation, a medical beamline and a laboratory are now being constructed at SPring-8 in Harima. 55 refs.

  1. Infrared synchrotron radiation from electron storage rings

    International Nuclear Information System (INIS)

    Duncan, W.D.; Williams, G.P.

    1983-01-01

    Simple and useful approximations, valid at infrared wavelengths, to the equations for synchrotron radiation are presented and used to quantify the brightness and power advantage of current synchrotron radiation light sources over conventional infrared broadband laboratory sources. The Daresbury Synchrotron Radiation Source (SRS) and the Brookhaven National Synchrotron Light Source (vacuum ultraviolet) [NSLS(VUV)] storage rings are used as examples in the calculation of the properties of infrared synchrotron radiation. The pulsed nature of the emission is also discussed, and potential areas of application for the brightness, power, and time structure advantages are presented. The use of infrared free electron lasers and undulators on the next generation of storage ring light sources is briefly considered

  2. Protein Data Bank depositions from synchrotron sources.

    Science.gov (United States)

    Jiang, Jiansheng; Sweet, Robert M

    2004-07-01

    A survey and analysis of Protein Data Bank (PDB) depositions from international synchrotron radiation facilities, based on the latest released PDB entries, are reported. The results (http://asdp.bnl.gov/asda/Libraries/) show that worldwide, every year since 1999, more than 50% of the deposited X-ray structures have used synchrotron facilities, reaching 75% by 2003. In this web-based database, all PDB entries among individual synchrotron beamlines are archived, synchronized with the weekly PDB release. Statistics regarding the quality of experimental data and the refined model for all structures are presented, and these are analysed to reflect the impact of synchrotron sources. The results confirm the common impression that synchrotron sources extend the size of structures that can be solved with equivalent or better quality than home sources.

  3. Protein Data Bank Depositions from Synchrotron Sources

    International Nuclear Information System (INIS)

    Jiang, J.; Sweet, R.

    2004-01-01

    A survey and analysis of Protein Data Bank (PDB) depositions from international synchrotron radiation facilities, based on the latest released PDB entries, are reported. The results ( ) show that worldwide, every year since 1999, more than 50% of the deposited X-ray structures have used synchrotron facilities, reaching 75% by 2003. In this web-based database, all PDB entries among individual synchrotron beamlines are archived, synchronized with the weekly PDB release. Statistics regarding the quality of experimental data and the refined model for all structures are presented, and these are analysed to reflect the impact of synchrotron sources. The results confirm the common impression that synchrotron sources extend the size of structures that can be solved with equivalent or better quality than home sources

  4. Extinction correction and synchrotron radiation

    International Nuclear Information System (INIS)

    Suortti, P.

    1983-01-01

    The primary extinction factor ysub(p) is defined as the ratio of the integrated reflection from a coherently diffracting domain to the integrated kinematical reflection from the same domain. When ysub(p) is larger than 0.5 it may be approximated by ysub(p)= exp[-(αdelta) 2 ], where α is about 0.5 and delta the average size of the coherent domain when measured in units of the extinction length Λ, delta = D/Λ. Transfer equations are applied to symmetrical Laue diffraction, and the reflectivity per unit length, sigma(epsilon) is solved from the measured reflecting ratio as a function of the rocking angle epsilon = theta -thetasub(B). Measurements with conventional x-ray sources are made on single crystal slabs of Be and Si using AgKβ, MoKα 1 and CuKα radiation. The primary extinction factor ysub(p)(epsilon) is solved from a point-by-point comparison of two measurements where the extinction length Λ is changed by varying the polarization and/or wavelength of the x-ray beam. The results show that primary and secondary extinction are strongly correlated, and that the customary assumption of independent size and orientation distributions of crystal mosaics is unjustified. The structure factors for Be and Si show close agreement with other recent measurements and calculations. The limitations of the method are discussed in length, particularly the effects of beam divergences and incoherence of the rays in the crystal. It is concluded that under typical experimental conditions the requirements of the theory are met. Practical limitations arising from the use of characteristic wavelengths and unpolarized radiation prohibit the use of the full potential of the method. The properties of a synchrotron radiation source are compared with a conventional x-ray source, and it is demonstrated that the experimental limitations can be removed by the use of synchrotron radiation. A diffraction experiment with synchrotron radiation is outlined, as well as generalization of the

  5. High heat load synchrotron optics

    International Nuclear Information System (INIS)

    Mills, D.M.

    1993-01-01

    Third generation synchrotron radiation sources currently being constructed worldwide will produce x-ray beams of unparalleled power and power density. These high heat fluxes coupled with the stringent dimensional requirements of the x-ray optical components pose a prodigious challenge to designers of x-ray optical elements, specifically x-ray mirrors and crystal monochromators. Although certain established techniques for the cooling of high heat flux components can be directly applied to this problem, the thermal management of high heat load x-ray optical components has several unusual aspects that may ultimately lead to unique solutions. This manuscript attempts to summarize the various approaches currently being applied to this undertaking and to point out the areas of research that require further development

  6. Medical application of Synchrotron Radiation

    International Nuclear Information System (INIS)

    Hyodo, Kazuyuki; Nishimura, Katsuyuki.

    1990-01-01

    The number of patients suffering from ischemic heart disease is also increasing rapidly in Japan. The standard method for assessing coronary artery diseases is the coronary angiography. Excellent images are taken by this method, however, it is an invasive method in which a catheter into a peripheral artery. The patients would obtain great benefit if the coronary arteries could be distinguished by intravenous injection of the contrast material. The K-edge subtraction method, which uses the K-edge discontinuity in the attenuation coefficient of the contrast material, is considered to be the most suitable method for coronary angiography by peripheral venous injection. Synchrotron Radiation (SR) is so intense that it allows selection of monochromatic X-rays, and studies on K-edge subtraction using SR has been started at some facilities. Recent activities K-edge subtraction method at the Accumulation Ring are briefly described here. (author)

  7. Synchrotron radiation and industrial research

    International Nuclear Information System (INIS)

    Townsend, R.P.

    1995-01-01

    Fundamental studies on the properties of many different materials are of prime importance to most industrial concerns. For Unilever, solids (crystalline and amorphous), soft solids and complex fluids are the materials of primary interest. Synchrotron radiation has proved of great value for the analysis of a variety of such materials, because the intense and highly collimated radiation source has enabled us to obtain structural information rapidly as well as in time-resolved mode. In this paper are outlined the types of materials problems faced, and how we use different techniques to elucidate structure (both short and long range order) in zeolites, amorphous solids, as well as in biomaterials such as skin and hair containing lipid phases. Both equilibrium and time-resolved studies are described. (orig.)

  8. Application of synchrotron radiation to elemental analysis

    International Nuclear Information System (INIS)

    Jones, K.W.; Gordon, B.M.; Hanson, A.L.; Hastings, J.B.; Howells, M.R.; Kraner, H.W.; Chen, J.R.

    1983-01-01

    The use of a synchrotron storage ring as a high brightness source for production of monoergic, variable energy, and highly polarized x-ray beams promises to revolutionize the field of elemental analysis. The results of exploratory work using the Cornell synchrotron facility, CHESS, will be described. Design considerations and features of the new X-Ray Microprobe Facility now under construction at the Brookhaven National Synchrotron Light Source will be presented. This facility will be used for bulk analysis and for microanalysis with an initial spatial resolution of the order of 30 μm

  9. Report of the Synchrotron Radiation Vacuum Workshop

    International Nuclear Information System (INIS)

    Avery, R.T.

    1984-06-01

    The Synchrotron Radiation Vacuum Workshop was held to consider two vacuum-related problems that bear on the design of storage rings and beam lines for synchrotron radiation facilities. These problems are gas desorption from the vacuum chamber walls and carbon deposition on optical components. Participants surveyed existing knowledge on these topics and recommended studies that should be performed as soon as possible to provide more definitive experimental data on these topics. This data will permit optimization of the final design of the Advanced Light Source (ALS) and its associated beam lines. It also should prove useful for other synchrotron radiation facilities as well

  10. Synchrotron radiation applications in biophysics and medicine

    International Nuclear Information System (INIS)

    Burattini, E.

    1985-01-01

    The peculiar properties of synchrotron radiation are briefly summarized. A short review on the possible applications of synchrotron radiation in two important fields like Biophysics and Medicine is presented. Details are given on experiments both in progress and carried out in many synchrotron radiation facilities, all over the world, using different techniques like X-ray absorption and fluorescence spectroscopy, X-ray fluorescence microanalysis, X-ray microscopy and digital subtraction angiography. Some news about the photon-activation therapy are briefly reported too

  11. Synchrotron power supply of TARN II

    International Nuclear Information System (INIS)

    Watanabe, Shin-ichi.

    1991-07-01

    The construction and performance of synchrotron power supply of TARN II are described. The 1.1 GeV synchrotron-cooler TARN II has been constructed at Institute for Nuclear Study, University of Tokyo. Constructed power supply for the dipole magnets is 600 V, 2500 A operated in the mode of trapezoid wave form with the repetition cycle of 0.1 Hz. The stability of magnetic field within 10 -3 and tracking error of 10 -4 have been attained with the aid of computer control system. First trial of synchrotron acceleration of He 2+ beam has been done up to 600 MeV in April, 1991. (author)

  12. The study of gravity makeup to RCS for the loss of RHR event during mid-loop operation

    International Nuclear Information System (INIS)

    Oh, H. S.; Yoon, D. J.; Ha, S. J.; Lee, C. S.

    2004-01-01

    In case of the loss of residual heat removal system (RHR) event during mid-loop operation, one of the mitigation actions to prevent core uncovery is gravity makeup to the RCS. This study includes the mitigation actions for gravity makeup to the RCS for 3-loop nuclear power plant, minimum gravity makeup flow for prevention of core boiling and core uncovery and possible pass of gravity make up. Also, the evaluation of minimum gravity makeup to prevent core boiling and core uncovery was performed using the RELAP/MOD3.2.2beta code. The results of this study show that the minimum flow to prevent core uncovery in case of cold leg injection (about 20m 3 /hr) is too small to recover the core water level. So, our conclusion is that the minimum flow to prevent core boiling (about 170m 3 /hr) is enough to recover core water level

  13. Electrophysiological studies of the feasibility of suprachoroidal-transretinal stimulation for artificial vision in normal and RCS rats.

    Science.gov (United States)

    Kanda, Hiroyuki; Morimoto, Takeshi; Fujikado, Takashi; Tano, Yasuo; Fukuda, Yutaka; Sawai, Hajime

    2004-02-01

    Assessment of a novel method of retinal stimulation, known as suprachoroidal-transretinal stimulation (STS), which was designed to minimize insult to the retina by implantation of stimulating electrodes for artificial vision. In 17 normal hooded rats and 12 Royal College of Surgeons (RCS) rats, a small area of the retina was focally stimulated with electric currents through an anode placed on the fenestrated sclera and a cathode inserted into the vitreous chamber. Evoked potentials (EPs) in response to STS were recorded from the surface of the superior colliculus (SC) with a silver-ball electrode, and their physiological properties and localization were studied. In both normal and RCS rats, STS elicited triphasic EPs that were vastly diminished by changing polarity of stimulating electrodes and abolished by transecting the optic nerve. The threshold intensity (C) of the EP response to STS was approximately 7.2 +/- 2.8 nC in normal and 12.9 +/- 7.7 nC in RCS rats. The responses to minimal STS were localized in an area on the SC surface measuring 0.12 +/- 0.07 mm(2) in normal rats and 0.24 +/- 0.12 mm(2) in RCS rats. The responsive area corresponded retinotopically to the retinal region immediately beneath the anodic stimulating electrode. STS is less invasive in the retina than stimulation through epiretinal or subretinal implants. STS can generate focal excitation in retinal ganglion cells in normal animals and in those with degenerated photoreceptors, which suggests that this method of retinal stimulation is suitable for artificial vision.

  14. Recommendations to increase customer conversion rates through website optimization and online marketing Case company: RCS Training Center

    OpenAIRE

    Bogdanova, Daria

    2016-01-01

    The goal of this thesis is to establish effective online marketing strategy for a small B2C wellness studio. The commissioning company RCS Training Center wishes to attract more customers through their website and social media sites, such as Facebook and Instagram. This objective is justified by the popularity of the wellness and fitness niche online, which creates big market potential in the homeland and internationally. However, popularity also means high competition. A lack of experience i...

  15. World Register of marine Cave Species (WoRCS: a new Thematic Species Database for marine and anchialine cave biodiversity

    Directory of Open Access Journals (Sweden)

    Vasilis Gerovasileiou

    2016-09-01

    Full Text Available Scientific exploration of marine cave environments and anchialine ecosystems over recent decades has led to outstanding discoveries of novel taxa, increasing our knowledge of biodiversity. However, biological research on underwater caves has taken place only in a few areas of the world and relevant information remains fragmented in isolated publications and databases. This fragmentation makes assessing the conservation status of marine cave species especially problematic, and this issue should be addressed urgently given the stresses resulting from planned and rampant development in the coastal zone worldwide. The goal of the World Register of marine Cave Species (WoRCS initiative is to create a comprehensive taxonomic and ecological database of known species from marine caves and anchialine systems worldwide and to present this as a Thematic Species Database (TSD of the World Register of marine Species (WoRMS. WoRCS will incorporate ecological data (e.g., type of environment, salinity regimes, and cave zone as well as geographical information on the distribution of species in cave and anchialine environments. Biodiversity data will be progressively assembled from individual database sources at regional, national or local levels, as well as from literature sources (estimate: >20,000 existing records of cave-dwelling species scattered in several databases. Information will be organized in the WoRCS database following a standard glossary based on existing terminology. Cave-related information will be managed by the WoRCS thematic editors with all data dynamically linked to WoRMS and its team of taxonomic editors. In order to mobilize data into global biogeographic databases, a Gazetteer of the Marine and Anchialine Caves of the World will be established. The presence records of species could be eventually georeferenced for submission to the Ocean Biogeographic Information System (OBIS and constitute an important dataset for biogeographical and

  16. Geological applications of synchrotron radiation

    Science.gov (United States)

    Henderson, C. M. B.; Cressey, G.; Redfern, S. A. T.

    1995-03-01

    Synchrotron-based, Earth sciences research carried out over the last 5 years is reviewed with special attention being given to X-ray absorption studies; X-ray diffraction and X-ray fluorescence microprobe applications are considered more briefly. A comprehensive bibliography is included. The main part of the paper summarizes recent work carried out at the Daresbury SRS. K-edge XAS studies of glasses as models for silicate melts provide information on the local structural environments of Si, Fe 2+ and Fe 3+. By analogy with synthetic "leucites" which contain Fe 2+ and Fe 3+ in tetrahedral framework sites, it seems that many model glasses also contain both oxidation states of Fe in the network, rather than as network modifiers. The structural sites occupied by the minor elements Mn, Zn and Ti in staurolite have been identified using XAFS; Mn and Zn substitute for Fe 2+ in the tetrahedral T2 site, while Ti occupies the distorted M2 octahedral site. L-edge spectroscopy is used to identify the valencies and electronic structures of Mn and Fe in minerals and the Fe 2+:Fe 3+ ratio in a natural spinel is determined. The polarized nature of the synchrotron beam is exploited in determining the Fe X-ray absorption anisotropy in single crystal tourmaline and epidote. XRD powder studies include Rietveld-refinement structure determination and compressibility studies. Synthetic "leucites" having the stoichiometry K 2MgSi 5O 12 have distinctly different structures. The dry-synthesized form is cubic Ia3d with Si and Mg fully disordered on tetrahedral framework sites, while the hydrothermally-synthesized polymorph is monoclinic P2 1/c with Si and Mg fully disordered on, respectively, 10 and 2 tetrahedral sites. The reversible tetragonal to orthorhombic phase transition in gillespite (BaFeSi 4O 10) has been studied in a diamond anvil cell using ED detection and found to occur at 1.2 ± 0.1 GPa. The anomalous compressibility observed has been interpreted in terms of ferroelastic and

  17. Stanford Synchrotron Radiation Light Source (SSRL)

    Data.gov (United States)

    Federal Laboratory Consortium — The SSRL at SLAC National Accelerator Laboratory was built in 1974 to take and use for synchrotron studies the intense x-ray beams from the SPEAR storage ring that...

  18. Molecular photoemission studies using synchrotron radiation

    International Nuclear Information System (INIS)

    Truesdale, C.M.

    1983-04-01

    The angular distributions of photoelectrons and Auger electrons were measured by electron spectroscopy using synchrotron radiation. The experimental results are compared with theoretical calculations to interpret the electronic behavior of photoionization for molecular systems

  19. National synchrotron light source VUV storage ring

    International Nuclear Information System (INIS)

    Blumberg, L.; Bittner, J.; Galayda, J.; Heese, R.; Krinsky, S.; Schuchman, J.; van Steenbergen, A.

    1979-01-01

    A 700 MeV electron storage ring designed for synchrotron radiation applications is described. Lattice and stability calculations are presented and the vacuum, correction and injection systems are discussed

  20. Applications of synchrotron radiation in Biophysics

    International Nuclear Information System (INIS)

    Bemski, G.

    1983-01-01

    A short introduction to the generation of the synchrotron radiation is made. Following, the applications of such a radiation in biophysics with emphasis to the study of the hemoglobin molecule are presented. (L.C.) [pt

  1. Simulation of synchrotron motion with rf noise

    International Nuclear Information System (INIS)

    Leemann, B.T.; Forest, E.; Chattopadhyay, S.

    1986-08-01

    The theoretical formulation is described that is behind an algorithm for synchrotron phase-space tracking with rf noise and some preliminary simulation results of bunch diffusion under rf noise obtained by actual tracking

  2. National Synchrotron Light Source annual report 1988

    Energy Technology Data Exchange (ETDEWEB)

    Hulbert, S.; Lazarz, N.; Williams, G. (eds.)

    1988-01-01

    This report discusses the experiment done at the National Synchrotron Light Source. Most experiments discussed involves the use of the x-ray beams to study physical properties of solid materials. (LSP)

  3. Synchrotron light sources in developing countries

    Science.gov (United States)

    Mtingwa, Sekazi K.; Winick, Herman

    2018-03-01

    We discuss the role that synchrotron light sources, such as SESAME, could play in improving the socioeconomic conditions in developing countries. After providing a brief description of a synchrotron light source, we discuss the important role that they played in the development of several economically emerging countries. Then we describe the state of synchrotron science in South Africa and that country’s leadership role in founding the African Light Source initiative. Next, we highlight a new initiative called Lightsources for Africa, the Americas & Middle East Project, which is a global initiative led by the International Union of Pure and Applied Physics and the International Union of Crystallography, with initial funding provided by the International Council for Science. Finally, we comment on a new technology called the multibend achromat that has launched a new paradigm for the design of synchrotron light sources that should be attractive for construction in developing countries.

  4. Synchrotrons are also devoted to the society

    International Nuclear Information System (INIS)

    Gacoin, M.P.; Cornuejols, D.; Cotte, M.; Deblay, P.; Mitchell, E.P.; McCarthy, J.; Fraissard, F.

    2013-01-01

    The ESRF and the SOLEIL synchrotrons are not only scientific instruments but also active players in the cultural and economic fields. This document gathers 6 short articles. The 2 first present the actions of SOLEIL and ESRS scientific teams towards the spreading of scientific knowledge in the public. The third article is dedicated to the uses of synchrotron radiation to the study of cultural objects to learn more about their fabrication, present state or the remedial actions that could be used to renovate them. The fourth and fifth articles present the contributions of ESRF and SOLEIL to the industrial world, in fact these contributions are not limited to the research field but also appear for quality assurance or the control of aging processes. Partnerships have been signed between both synchrotrons and enterprises to develop industrial products based on instrumentation or on the use of synchrotron radiation. The last article describes the procedure to have access to both facilities. (A.C.)

  5. Synchrotrons are also devoted to society

    International Nuclear Information System (INIS)

    Gacoin, M.P.; Cornuejols, D.; Cotte, M.; Deblay, P.; Mitchell, E.P.; McCarthy, J.; Fraissard, F.

    2013-01-01

    The ESRF and the SOLEIL synchrotrons are not only scientific instruments but also active players in the cultural and economic fields. This document gathers 6 short articles. The 2 first present the actions of SOLEIL and ESRS scientific teams towards the spreading of scientific knowledge in the public. The third article is dedicated to the uses of synchrotron radiation to the study of cultural objects to learn more about their fabrication, present state or the remedial actions that could be used to renovate them. The fourth and fifth articles present the contributions of ESRF and SOLEIL to the industrial world, in fact these contributions are not limited to the research field but also appear for quality assurance or the control of aging processes. Partnerships have been signed between both synchrotrons and enterprises to develop industrial products based on instrumentation or on the use of synchrotron radiation. The last article describes the procedure to have access to both facilities. (A.C.)

  6. Evaluation of the synchrotron close orbit

    International Nuclear Information System (INIS)

    Bashmakov, Yu.A.; Karpov, V.A.

    1991-01-01

    The knowledge of the closed orbit position is an essential condition for the effective work of any accelerator. Therefore questions of calculations, measurements and controls have great importance. For example, during injection of particles into a synchrotron, the amplitudes of their betatron oscillations may become commensurable with the working region of the synchrotron. This makes one pay attention at the problem of formation of the optimum orbit with use of correcting optical elements. In addition, it is often necessary to calculate such an orbit at the end of the acceleration cycle when particles are deposited at internal targets or removed from the synchrotron. In this paper, the computation of the close orbit is reduced to a determination at an arbitrarily chosen azimuth of the eigenvector of the total transfer matrix of the synchrotron ring and to tracing with this vector desired orbit. The eigenvector is found as a result of an iteration

  7. Fiber structural analysis by synchrotron radiation

    CERN Document Server

    Kojima, J I; Kikutani, T

    2003-01-01

    Topics of fiber structural analysis by synchrotron radiation are explained. There are only three synchrotron radiation facilities in the world, SPring-8 (Super Photon ring-8) in Japan, APS (Advanced Photon Source) in U.S.A. and ESRF (European Synchrotron Radiation Facility) in France. Online measurement of melt spinning process of PET and Nylon6 is explained in detail. Polypropylene and PBO (poly-p-phenylenebenzobisoxazole) was measured by WAXD (Wide Angle X-ray Diffraction)/SAXS (Small Angle X-ray Scattering) at the same time. Some examples of measure of drawing process of fiber are described. The structure formation process of spider's thread was measured. Micro beam of X-ray of synchrotron facility was improved and it attained to 65nm small angle resolving power by 10 mu m beamsize. (S.Y.)

  8. Panel backs next-generation synchrotron

    CERN Multimedia

    Service, R F

    1999-01-01

    A key federal panel recommended continued research into development of a fourth-generation synchrotron. It would be capable of creating x-ray pulses billions of times more intense than current designs (1 page).

  9. A Study on Temperature Distribution in the Hot Leg Pipes considering the Variation of Flow Rate in RCS

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Hyuksu; Yi, Kunwoo; Choe, Yoonjae; Jang, Hocheol; Yune, Seokjeong; Park, Seongchan [KEPCO Engineering and Construction, Daejeon (Korea, Republic of)

    2016-10-15

    In this study, a computational analysis is performed to predict the deviation in the temperature distribution in the hot leg pipe according to the flow rate variation in RCS. In the hot leg pipes of Reactor Coolant System (RCS) of APR1400, four Resistance Temperature Detectors (RTDs), to obtain the average hot leg temperature, are installed at each hot leg pipe (two in the upper region and the other two in the lower region around the wall of the hot leg pipe). There is a deviation in temperature distribution in the hot leg pipe due to the sudden changes in the flow direction and area from the reactor core exit to the hot leg pipe. The non-uniform temperature distribution in the hot leg pipe can affect the measurement of the plant parameters such as the reactor power and the reactor coolant flow rate. The following conclusions are reached 1) The non-uniform temperature distribution in the core exit is sustained to some extent through the entire region of hot leg pipe. 2) The temperature ranges having a uniform pattern are 45 - 120° and 240 - 315°. The sensor positions of RTDs are located in this interval (45 - 120° and 240 - 315°) and this sensor positions of RTDs show the appropriate temperature measurement. Also, the temperature distribution shows the similar pattern without reference to the flow rate variation in RCS.

  10. Evaluation of a coolant injection into the in-vessel with a RCS depressurization by using SCDAP/RELAP5

    International Nuclear Information System (INIS)

    Rae-Joon, Park; Sang-Baik, Kim; Hee-Dong, Kim

    2007-01-01

    As part of the evaluations of a severe accident management strategy, a coolant injection in the vessel with a reactor coolant system (RCS) depressurization has been evaluated by using the SCDAP/RELAP5 computer code. Two high pressure sequences of a small break loss of coolant accident (LOCA) without safety injection (SI) and a total loss of feed water (LOFW) accident have been analyzed in optimized power reactor OPR-1000. The SCDAP/RELAP5 results have shown that only one train operation of a high pressure safety injection at 30,000 seconds with a RCS depressurization by using one condenser dump valve at 6 minutes after an entrance of the severe accident management guidance prevents a reactor vessel failure for the small break LOCA without SI. In this case, only train operation of the low pressure safety injection (LPSI) without the high pressure safety injection (HPSI) does not prevent a reactor vessel failure. Only one train operation of the HPSI at 20,208 seconds with a RCS depressurization by using two safety depressurization system valves at 40 minutes after an initial opening of the safety relief valve prevents a reactor vessel failure for the total LOFW. (authors)

  11. New theoretical results in synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Bagrov, V.G. [Tomsk State University, Lenin Avenue 36, 634050 Tomsk (Russian Federation)]. E-mail: bagrov@phys.tsu.ru; Gitman, D.M. [Instituto de Fisica, Universidade de Sao Paulo, C.P. 66318, 05315-970 Sao Paulo, SP (Brazil); Tlyachev, V.B. [Tomsk Institute of High Current Electronics, Akademicheskiy Avenue 4, Tomsk (Russian Federation); Jarovoi, A.T. [Tomsk State University, Lenin Avenue 36, 634050 Tomsk (Russian Federation)

    2005-11-15

    One of the remarkable features of the relativistic electron synchrotron radiation is its concentration in small angle {delta}{approx}1/{gamma} (here {gamma}-relativistic factor: {gamma}=E/mc{sup 2}, E - energy, m - electron rest mass, c - light velocity) near rotation orbit plane [V.G. Bagrov, V.A. Bordovitsyn, V.G. Bulenok, V. Ya. Epp, Kinematical projection of pulsar synchrotron radiation profiles, in: Proceedings of IV ISTC Scientific Advisory Commitee Seminar on Basic Science in ISTC Aktivities, Akademgorodok, Novosibirsk, April 23-27, 2001, p. 293-300]. This theoretically predicted and experimentally confirmed feature is peculiar to total (spectrum summarized) radiating intensity. This angular distribution property has been supposed to be (at least qualitatively) conserved and for separate spectrum synchrotron radiation components. In the work of V.G. Bagrov, V.A. Bordovitsyn, V. Ch. Zhukovskii, Development of the theory of synchrotron radiation and related processes. Synchrotron source of JINR: the perspective of research, in: The Materials of the Second International Work Conference, Dubna, April 2-6, 2001, pp. 15-30 and in Angular dependence of synchrotron radiation intensity. http://lanl.arXiv.org/abs/physics/0209097, it is shown that the angular distribution of separate synchrotron radiation spectrum components demonstrates directly inverse tendency - the angular distribution deconcentration relatively the orbit plane takes place with electron energy growth. The present work is devoted to detailed investigation of this situation. For exact quantitative estimation of angular concentration degree of synchrotron radiation the definition of radiation effective angle and deviation angle is proposed. For different polarization components of radiation the dependence of introduced characteristics was investigated as a functions of electron energy and number of spectrum component.

  12. Experimental demonstration of the KEK induction synchrotron

    International Nuclear Information System (INIS)

    Takayama, Ken; Torikai, Kota; Shimosaki, Yoshito; Kono, Tadaaki; Iwashita, Taiki; Arakida, Yoshio; Nakamura, Eiji; Shirakata, Masashi; Sueno, Takeshi; Wake, Masayoshi; Otsuka, Kazunori

    2007-01-01

    Recent progress in the KEK induction synchrotron is presented. In the recent experiment, by using a newly developed induction acceleration system instead of radio-wave acceleration devices, a single proton bunch injected from the 500 MeV Booster ring and captured by the barrier bucket created by the induction step-voltages was accelerated to 6 GeV in the KEK proton synchrotron

  13. Early British synchrotrons, an informal history

    International Nuclear Information System (INIS)

    Lawson, J.D.

    1997-02-01

    An historical account of the design and construction of early synchrotrons in the United Kingdom, based partly on personal reminiscences, is presented. Material is also drawn from archives at Birmingham and CERN. The document covers the period from plans for the world's first synchrotron at Malvern after the Second World War to work done at Harwell Laboratory for CERN in the period 1951-1953. (UK)

  14. Synchrotron control system of the HIMAC

    International Nuclear Information System (INIS)

    Takada, E.; Sato, K.; Itano, A.

    1994-01-01

    A structural design synopsis and the present status of the HIMAC synchrotron control system are described. The control system comprises of Timing System, (ring magnet) Power-supply Controller, Programmable Logic Controller, Static Var Compensator controller, Monitor Controller, RF control computer, Beam Transport control computer and the synchrotron main computer (denoted as CS, hereafter) that forms a local area cluster with man-machine interfacing computers, and communicates with HIMAC supervisor computer. (author)

  15. Recent Developments in Synchrotron Moessbauer Reflectometry

    Energy Technology Data Exchange (ETDEWEB)

    Deak, L.; Bottyan, L.; Major, M.; Nagy, D. L. [KFKI Research Institute for Particle and Nuclear Physics (Hungary); Spiering, H. [Johannes Gutenberg Universitaet, Mainz, Institute fuer Anorganische und Analytische Chemie (Germany); Szilagyi, E.; Tancziko, F. [KFKI Research Institute for Particle and Nuclear Physics (Hungary)

    2002-12-15

    Synchrotron Moessbauer Reflectometry (SMR), the grazing incidence nuclear resonant scattering of synchrotron radiation, can be applied to perform depth-selective phase analysis and to determine the isotopic and magnetic structure of thin films and multilayers. Principles and methodological aspects of SMR are briefly reviewed. Off-specular SMR provides information from the lateral structure of multilayers. In anti-ferromagneticly coupled systems the size of magnetic domains can be measured.

  16. National Laboratory of Synchrotron Radiation: technologic potential

    International Nuclear Information System (INIS)

    Silva, C.E.T.G. da; Rodrigues, A.R.D.

    1987-01-01

    The technological or industrial developments based on the accumulated experience by research group of condensed matter physics, in Brazil, are described. The potential of a National Laboratory of Synchrotron Radiation for personnel training, absorption and adaptation of economically important technologies for Brazil, is presented. Examples of cooperations between the Laboratory and some national interprises, and some industrial applications of the synchrotron radiation are done. (M.C.K.) [pt

  17. Effects on RCS of a perfect electromagnetic conductor sphere in the presence of anisotropic plasma layer

    Science.gov (United States)

    Ghaffar, A.; Hussan, M. M.; Illahi, A.; Alkanhal, Majeed A. S.; Ur Rehman, Sajjad; Naz, M. Y.

    2018-01-01

    Effects on RCS of perfect electromagnetic conductor (PEMC) sphere by coating with anisotropic plasma layer are studied in this paper. The incident, scattered and transmitted electromagnetic fields are expanded in term of spherical vector wave functions using extended classical theory of scattering. Co and cross-polarized scattered field coefficients are obtained at the interface of free space-anisotropic plasma and at anisotropic plasma-PEMC sphere core by scattering matrices method. The presented analytical expressions are general for any perfect conducting sphere (PMC, PEC, or PEMC) with general anisotropic/isotropic material coatings that include plasma and metamaterials. The behavior of the forward and backscattered radar cross section of PEMC sphere with the variation of the magnetic field strength, incident frequency, plasma density, and effective collision frequency for the co-polarized and the cross polarized fields are investigated. It is also observed from the obtained results that anisotropic layer on PEMC sphere shows reciprocal behavior as compared to isotopic plasma layer on PEMC sphere. The comparisons of the numerical results of the presented analytical expressions with available results of some special cases show the correctness of the analysis.

  18. Chronic intravitreous infusion of ciliary neurotrophic factor modulates electrical retinal stimulation thresholds in the RCS rat.

    Science.gov (United States)

    Kent, Tiffany L; Glybina, Inna V; Abrams, Gary W; Iezzi, Raymond

    2008-01-01

    To determine whether the sustained intravitreous delivery of CNTF modulates cortical response thresholds to electrical retinal stimulation in the RCS rat model of retinal degeneration. Animals were assigned to four groups: untreated, nonsurgical control and infusion groups of 10 ng/d CNTF, 1 ng/d CNTF, and PBS vehicle control. Thresholds for electrically evoked cortical potentials (EECPs) were recorded in response to transcorneal electrical stimulation of the retina at p30 and again at p60, after a three-week infusion. As the retina degenerated over time, EECP thresholds in response to electrical retinal stimulation increased. Eyes treated with 10 ng/d CNTF demonstrated significantly greater retinal sensitivity to electrical stimulation when compared with all other groups. In addition, eyes treated with 1 ng/d CNTF demonstrated significantly greater retinal sensitivity than both PBS-treated and untreated control groups. Retinal sensitivity to electrical stimulation was preserved in animals treated with chronic intravitreous infusion of CNTF. These data suggest that CNTF-mediated retinal neuroprotection may be a novel therapy that can lower stimulus thresholds in patients about to undergo retinal prosthesis implantation. Furthermore, it may maintain the long-term efficacy of these devices in patients.

  19. Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats.

    Science.gov (United States)

    Lund, Raymond D; Wang, Shaomei; Klimanskaya, Irina; Holmes, Toby; Ramos-Kelsey, Rebeca; Lu, Bin; Girman, Sergej; Bischoff, N; Sauvé, Yves; Lanza, Robert

    2006-01-01

    Embryonic stem cells promise to provide a well-characterized and reproducible source of replacement tissue for human clinical studies. An early potential application of this technology is the use of retinal pigment epithelium (RPE) for the treatment of retinal degenerative diseases such as macular degeneration. Here we show the reproducible generation of RPE (67 passageable cultures established from 18 different hES cell lines); batches of RPE derived from NIH-approved hES cells (H9) were tested and shown capable of extensive photoreceptor rescue in an animal model of retinal disease, the Royal College of Surgeons (RCS) rat, in which photoreceptor loss is caused by a defect in the adjacent retinal pigment epithelium. Improvement in visual performance was 100% over untreated controls (spatial acuity was approximately 70% that of normal nondystrophic rats) without evidence of untoward pathology. The use of somatic cell nuclear transfer (SCNT) and/or the creation of banks of reduced complexity human leucocyte antigen (HLA) hES-RPE lines could minimize or eliminate the need for immunosuppressive drugs and/or immunomodulatory protocols.

  20. Applications of β-gal-III isozyme from Bacillus coagulans RCS3, in lactose hydrolysis.

    Science.gov (United States)

    Batra, Navneet; Singh, Jagtar; Joshi, Amit; Bhatia, Sonu

    2011-12-01

    Bacillus coagulans RCS3 isolated from hot water springs secreted five isozymes i.e. β-gal I-V of β-galactosidase. β-gal III isozyme was purified using DEAE cellulose and Sephadex G 100 column chromatography. Its molecular weight characterization showed a single band at 315kD in Native PAGE, while two subunits of 50.1 and 53.7 kD in SDS PAGE. β-Gal III had pH optima in the range of 6-7 and temperature optima at 65°C. It preferred nitro-aryl-β-d-galactoside as substrate having K(m) of 4.16 mM with ONPG. More than 85% and 80% hydrolysis of lactose (1-5%, w/v) was recorded within 48 h of incubation at 55°C and 50°C respectively and pH range of 6-7. About 78-86% hydrolysis of lactose in various brands of standardized milk was recorded at incubation temperature of 50°C. These results marked the applications of β-gal III in processing of milk/whey industry. Copyright © 2011 Elsevier B.V. All rights reserved.

  1. Alumina Ceramics Vacuum Duct for the 3GeV-RCS of the J-PARC

    CERN Document Server

    Kinsho, Michikazu; Ogiwara, Norio; Saito, Yoshio

    2005-01-01

    It was success to develop alumina ceramics vacuum ducts for the 3GeV-RCS of J-PARC at JAERI. There are two types of alumina ceramics vacuum ducts needed, one being 1.5m-long duct with a circular cross section for use in the quadrupole magnet, the other being 3.5m-long and bending 15 degrees, with a race-track cross section for use in the dipole magnet. These ducts could be manufactured by joining several duct segments of 0.5-0.8 m in length by brazing. The alumina ceramics ducts have copper stripes on the outside surface of the ducts to reduce the duct impedance. One of the ends of each stripe is connected to a titanium flange by way of a capacitor so to interrupt an eddy current circuit. The copper stripes are produced by an electroforming method in which a stripe pattern formed by Mo-Mn metallization is first sintered on the exterior surface and then overlaid by PR-electroformed copper (Periodic current Reversal electroforming method). In order to reduce emission of secondary electrons when protons or elect...

  2. Synchrotron radiation from spherically accreting black holes

    International Nuclear Information System (INIS)

    Ipser, J.R.; Price, R.H.

    1982-01-01

    Spherical accretion onto a Schwartzchild black hole, of gas with frozen-in magnetic field, is studied numerically and analytically for a range of hole masses and accretion rates in which synchrotron emission is the dominant radiative mechanism. At small radii the equipartition of magnetic, kinetic, and gravitational energy is assumed to apply, and the gas is heated by dissipation of infalling magnetic energy, turbulent energy, etc. The models can be classified into three types: (a) synchrotron cooling negligible, (b) synchrotron cooling important but synchrotron self-absorption negligible, (c) synchrotron cooling and self-absorption important. In the first case gas temperatures become very high near the horizon but luminosity efficiencies (luminosity/mass-energy accretion rate) are low. In cases (b) and (c) the gas flow near the horizon is essentially isothermal and luminosity efficiencies are fairly high. The analysis and results for the isothermal cases (b) and (c) are valid only for moderate dissipative heating and synchrotron self-absorption. If self-absorption is very strong or if dissipated energy is comparable to infall energy, Comptonization effects, not included in the analysis, become important

  3. Starting up the Saturne synchrotron

    International Nuclear Information System (INIS)

    Salvat, M.

    1958-02-01

    Illustrated by many drawings and graphs, this report describes and comments all operations and measurements to be performed for starting up the Saturne synchrotron until particle acceleration exclusively. The author reports the study of beam as it goes out of the Van de Graaff: experiment of position and stability of the beam axis, study of beam current and geometric characteristics (calibration of the induction probe), experiment of mass separation and proton percentage, and adjustment of regulation and Van de Graaff fall law. In a second part, he reports the optics alignment and the study of optics property (installation of the different sectors, study of inflector end voltage, and influence of inflector position in the chamber). The third part addresses the examination of phenomena associated with injection: injection method and definition of the initial instant, search for injection optimum conditions, study of particle lifetime and of phenomena on the inner probe. The fourth part proposes theoretical additional elements regarding the movement of particles at the injection in the useful area, and phenomena occurring on targets and on the inner probe

  4. ROSY - Rossendorf synchrotron radiation source

    International Nuclear Information System (INIS)

    Einfeld, D.; Matz, W.

    1993-11-01

    The electron energy of the storage ring will be 3 GeV and the emitted synchrotron radiation is in the hard X-ray region with a critical energy of the spectrum of E c =8,4 keV (λ c =0,14 nm). With a natural emittance of 28 π nm rad ROSY emits high brilliance radiation. Besides the radiation from bending magnets there will be the possibility for using radiation from wigglers and undulators. For the insertion devices 8 places are foreseen four of which are located in non-dispersion-free regions. The storage ring is of fourfold symmetry, has a circumference of 148 m and is designed in a modified FODO structure. An upgrade of ROSY with superconducting bending magnets in order to shift the spectrum to higher energy can easily be done. Part I contains the scientific case and a description of the planned use of the beam lines. Part II describes the design of the storage ring and its components in more detail. (orig.) [de

  5. Synchrotron radiation applications in medical research

    International Nuclear Information System (INIS)

    Thomlinson, W.

    1995-01-01

    The medical projects employing synchrotron radiation as discussed in this paper are, for the most part, still in their infancies and no one can predict the direction in which they will develop. Both the basic research and applied medical programs are sure to be advanced at the new facilities coming on line, especially the ESRF and Spring- 8. However, success is not guaranteed. There is a lot of competition from advances in conventional imaging with the development of digital angiography, computed tomography, functional magnetic resonance imaging and ultrasound. The synchrotron programs will have to provide significant advantages over these modalities in order to be accepted by the medical profession. Advances in image processing and potentially the development of compact sources will be required in order to move the synchrotron developed imaging technologies into the clinical world. In any event, it can be expected that the images produced by the synchrotron technologies will establish ''gold standards'' to be targeted by conventional modalities. A lot more work needs to be done in order to bring synchrotron radiation therapy and surgery to the level of human studies and, subsequently, to clinical applications

  6. Metrology of reflection optics for synchrotron radiation

    International Nuclear Information System (INIS)

    Takacs, P.Z.

    1985-09-01

    Recent years have seen an almost explosive growth in the number of beam lines on new and existing synchrotron radiation facilities throughout the world. The need for optical components to utilize the unique characteristics of synchrotron radiation has increased accordingly. Unfortunately, the technology to manufacture and measure the large, smooth, exotic optical surfaces required to focus and steer the synchrotron radiation beam has not progressed as rapidly as the operational demands on these components. Most companies do not wish to become involved with a project that requires producing a single, very expensive, aspheric optic with surface roughness and figure tolerances that are beyond their capabilities to measure. This paper will review some of the experiences of the National Synchrotron Light Source in procuring grazing incidence optical components over the past several years. We will review the specification process - how it is related to the function of the optic, and how it relates to the metrology available during the manufacturing process and after delivery to the user's laboratory. We will also discuss practical aspects of our experience with new technologies, such as single point diamond turning of metal mirrors and the use of SiC as a mirror material. Recent advances in metrology instrumentation have the potential to move the measurement of surface figure and finish from the research laboratory into the optical shop, which should stimulate growth and interest in the manufacturing of optics to meet the needs of the synchrotron radiation user community

  7. Synchrotron radiation and prospects of its applications

    Energy Technology Data Exchange (ETDEWEB)

    Kulipanov, G; Skrinskii, A

    1981-04-01

    Current and prospective applications are described of synchrotron radiation resulting from the motion of high-energy electrons or positrons in a magnetic field and covering a wide spectral range from the infrared to X-ray. The advantages of the synchrotron radiation include a big source luminance, a small angular divergence, the possibility of calculating the absolute intensity and the spectral distribution of the radiation. Special storage rings are most suitable as a source. Synchrotron radiation is applied in X-ray microscopy, energy diffractometry, atomic and molecular spectroscopy, in the structural analysis of microcrystals, very rapid diffractometry of biological objects and crystals, and in Moessbauer spectroscopy. The prospective applications include uses in metrology, medicine, X-ray lithography, elemental analysis, molecular microsurgery, and in radiation technology.

  8. Chemical applications of synchrotron radiation: Workshop report

    International Nuclear Information System (INIS)

    1989-04-01

    The most recent in a series of topical meetings for Advanced Photon Source user subgroups, the Workshop on Chemical Applications of Synchrotron Radiation (held at Argonne National Laboratory, October 3-4, 1988) dealt with surfaces and kinetics, spectroscopy, small-angle scattering, diffraction, and topography and imaging. The primary objectives were to provide an educational resource for the chemistry community on the scientific research being conducted at existing synchrotron sources and to indicate some of the unique opportunities that will be made available with the Advanced Photon Source. The workshop organizers were also interested in gauging the interest of chemists in the field of synchrotron radiation. Interest expressed at the meeting has led to initial steps toward formation of a Chemistry Users Group at the APS. Individual projects are processed separately for the data bases

  9. Space-charge calculations in synchrotrons

    Energy Technology Data Exchange (ETDEWEB)

    Machida, S.

    1993-05-01

    One obvious bottleneck of achieving high luminosity in hadron colliders, such as the Superconducting Super Collider (SSC), is the beam emittance growth, due to space-charge effects in low energy injector synchrotrons. Although space-charge effects have been recognized since the alternating-gradient synchrotron was invented, and the Laslett tune shift usually calculated to quantify these effects, our understanding of the effects is limited, especially when the Laslett tune shift becomes a large fraction of the integer. Using the Simpsons tracking code, which we developed to study emittance preservation issues in proton synchrotrons, we investigated space-charge effects in the SSC Low Energy Booster (LEB). We observed detailed dependence on parameters such as beam intensity, initial emittance, injection energy, lattice function, and longitudinal motion. A summary of those findings, as well as the tracking technique we developed for the study, are presented.

  10. Fifth school on Magnetism and Synchrotron Radiation

    CERN Document Server

    Beaurepaire, Eric; Scheurer, Fabrice; Kappler, Jean-Paul; Magnetism and Synchrotron Radiation : New Trends

    2010-01-01

    Advances in the synthesis of new materials with often complex, nano-scaled structures require increasingly sophisticated experimental techniques that can probe the electronic states, the atomic magnetic moments and the magnetic microstructures responsible for the properties of these materials. At the same time, progress in synchrotron radiation techniques has ensured that these light sources remain a key tool of investigation, e.g. synchrotron radiation sources of the third generation are able to support magnetic imaging on a sub-micrometer scale. With the Fifth Mittelwihr School on Magnetism and Synchrotron Radiation the tradition of teaching the state-of-the-art on modern research developments continues and is expressed through the present set of extensive lectures provided in this volume. While primarily aimed at postgraduate students and newcomers to the field, this volume will also benefit researchers and lecturers actively working in the field.

  11. Chemical applications of synchrotron radiation: Workshop report

    Energy Technology Data Exchange (ETDEWEB)

    1989-04-01

    The most recent in a series of topical meetings for Advanced Photon Source user subgroups, the Workshop on Chemical Applications of Synchrotron Radiation (held at Argonne National Laboratory, October 3-4, 1988) dealt with surfaces and kinetics, spectroscopy, small-angle scattering, diffraction, and topography and imaging. The primary objectives were to provide an educational resource for the chemistry community on the scientific research being conducted at existing synchrotron sources and to indicate some of the unique opportunities that will be made available with the Advanced Photon Source. The workshop organizers were also interested in gauging the interest of chemists in the field of synchrotron radiation. Interest expressed at the meeting has led to initial steps toward formation of a Chemistry Users Group at the APS. Individual projects are processed separately for the data bases.

  12. Characterization of the rcsA Gene from Pantoea sp. Strain PPE7 and Its Influence on Extracellular Polysaccharide Production and Virulence on Pleurotus eryngii

    Directory of Open Access Journals (Sweden)

    Min Keun Kim

    2017-06-01

    Full Text Available RcsA is a positive activator of extracellular polysaccharide (EPS synthesis in the Enterobacteriaceae. The rcsA gene of the soft rot pathogen Pantoea sp. strain PPE7 in Pleurotus eryngii was cloned by PCR amplification, and its role in EPS synthesis and virulence was investigated. The RcsA protein contains 3 highly conserved domains, and the C-terminal end of the open reading frame shared significant amino acid homology to the helix-turn-helix DNA binding motif of bacterial activator proteins. The inactivation of rcsA by insertional mutagenesis created mutants that had decreased production of EPS compared to the wild-type strain and abolished the virulence of Pantoea sp. strain PPE7 in P. eryngii. The Pantoea sp. strain PPE7 rcsA gene was shown to strongly affect the formation of the disease symptoms of a mushroom pathogen and to act as the virulence factor to cause soft rot disease in P. eryngii.

  13. Coherent Synchrotron Radiation: Theory and Simulations

    International Nuclear Information System (INIS)

    Novokhatski, Alexander

    2012-01-01

    The physics of coherent synchrotron radiation (CSR) emitted by ultra-relativistic electron bunches, known since the last century, has become increasingly important with the development of high peak current free electron lasers and shorter bunch lengths in storage rings. Coherent radiation can be described as a low frequency part of the familiar synchrotron radiation in bending magnets. As this part is independent of the electron energy, the fields of different electrons of a short bunch can be in phase and the total power of the radiation will be quadratic with the number of electrons. Naturally the frequency spectrum of the longitudinal electron distribution in a bunch is of the same importance as the overall electron bunch length. The interest in the utilization of high power radiation from the terahertz and far infrared region in the field of chemical, physical and biological processes has led synchrotron radiation facilities to pay more attention to the production of coherent radiation. Several laboratories have proposed the construction of a facility wholly dedicated to terahertz production using the coherent radiation in bending magnets initiated by the longitudinal instabilities in the ring. Existing synchrotron radiation facilities also consider such a possibility among their future plans. There is a beautiful introduction to CSR in the 'ICFA Beam Dynamics Newsletter' N 35 (Editor C. Biscari). In this paper we recall the basic properties of CSR from the theory and what new effects, we can get from the precise simulations of the coherent radiation using numerical solutions of Maxwell's equations. In particular, transverse variation of the particle energy loss in a bunch, discovered in these simulations, explains the slice emittance growth in bending magnets of the bunch compressors and transverse de-coherence in undulators. CSR may play same the role as the effect of quantum fluctuations of synchrotron radiation in damping rings. It can limit the minimum

  14. Synchrotron environmental laboratory (SUL) at Anka

    International Nuclear Information System (INIS)

    Denecke, M.A.

    2002-01-01

    A research facility dedicated to environmental/geochemical research, the Synchrotron Environmental Laboratory (SUL), is planned to be installed and operated at ANKA. ANKA is the new synchrotron facility at the Research Centre Karlsruhe (FZK), Karlsruhe, Germany. ANKA is now in commissioning and planning operations for the fall of 2000. As the Institute for Nuclear Waste Disposal (INE) at FZK conducts a vigorous synchrotron-based research programme, INE was instrumental in the original impetus for installing such a facility at ANKA. These research activities at INE concentrate on actinide speciation in nuclear waste forms, geological media and geochemical model systems. In order for INE to direct their synchrotron research activities to ANKA, equipment and licensing required for performing experiments on actinide-containing samples is required. One great advantage of performing experiments on actinide-containing samples at ANKA is that the INE radiological laboratories lie in the near vicinity of the facility. This will minimise transport hazards and costs and allow experiments to be performed on samples whose characteristics may change with time. Experiments on radioactive samples with activities below the exemption level, according to German regulations, will be possible at ANKA at the start of operations. Licensing for work on higher levels of activity will be applied for in the future. The decades of experience in radiological work at FZK will facilitate development of procedure and equipment as prerequisites to licensing. A consortium of synchrotron radiation-user groups with environmental research interests has specified their requirements and needs for this facility. This scientific case serves as the foundation for the SUL design and is the basis for an application for federal funding. The SUL design reflects the heterogeneity and complexity of challenges facing researchers in the environmental/geochemical sciences. X-ray absorption fine structure (XAFS

  15. Overview of Industrial Synchrotron Radiation Use

    Science.gov (United States)

    Laderman, Stephen S.

    1996-03-01

    Relevant, reliable and accessible synchrotron radiation methods can play an important role in industrial activities. To date, the application of synchrotron radiation based materials characterization methods by industrial concerns has followed the path of laboratory based x-ray methods: early adoption, continuous improvement, and a high degree of specialization to meet specific goals, which may change over time. Like all x-ray methods, their applicability to segments of the biotechnology, chemical, electronics, medical and metallurgical industries arises from a need to develop sophisticated processes for precisely controlling microstructures. An increasing number of those processes are being developed in ways which can, in principle, be more effectively studied if synchrotron radiation based analyses are performed. Technical limitations confined the efforts of early synchrotron radiation users to long-range research investigations. Nowadays, progress in data collection methods, analysis algorithims, accelerator performance, and worker training, have removed many constraints. However, commercial technologies are being improved at steadily higher rates, shortening the time between research, development and manufacturing and, in many cases, blurring their distinctions. Certainly, rapid rates of innovation increase the opportunities for synchrotron radiation techniques to bring competitive advantage since they can be used to shrink development times, to maintain yields and, perhaps, as part of advanced manufacturing. At the same time, rapid rates of innovation also impose stringent criteria on the reliability and timeliness of the supporting methods. Successful conventional x-ray methods have resulted from efforts to create useful new capabilities that effectively balance such forces. Currently, synchrotron radiation users throughout the world are pursuing analogous goals.

  16. Analytical research using synchrotron radiation based techniques

    International Nuclear Information System (INIS)

    Jha, Shambhu Nath

    2015-01-01

    There are many Synchrotron Radiation (SR) based techniques such as X-ray Absorption Spectroscopy (XAS), X-ray Fluorescence Analysis (XRF), SR-Fourier-transform Infrared (SRFTIR), Hard X-ray Photoelectron Spectroscopy (HAXPS) etc. which are increasingly being employed worldwide in analytical research. With advent of modern synchrotron sources these analytical techniques have been further revitalized and paved ways for new techniques such as microprobe XRF and XAS, FTIR microscopy, Hard X-ray Photoelectron Spectroscopy (HAXPS) etc. The talk will cover mainly two techniques illustrating its capability in analytical research namely XRF and XAS. XRF spectroscopy: XRF spectroscopy is an analytical technique which involves the detection of emitted characteristic X-rays following excitation of the elements within the sample. While electron, particle (protons or alpha particles), or X-ray beams can be employed as the exciting source for this analysis, the use of X-ray beams from a synchrotron source has been instrumental in the advancement of the technique in the area of microprobe XRF imaging and trace level compositional characterisation of any sample. Synchrotron radiation induced X-ray emission spectroscopy, has become competitive with the earlier microprobe and nanoprobe techniques following the advancements in manipulating and detecting these X-rays. There are two important features that contribute to the superb elemental sensitivities of microprobe SR induced XRF: (i) the absence of the continuum (Bremsstrahlung) background radiation that is a feature of spectra obtained from charged particle beams, and (ii) the increased X-ray flux on the sample associated with the use of tunable third generation synchrotron facilities. Detection sensitivities have been reported in the ppb range, with values of 10 -17 g - 10 -14 g (depending on the particular element and matrix). Keeping in mind its demand, a microprobe XRF beamline has been setup by RRCAT at Indus-2 synchrotron

  17. Spectroscopic characterization of galaxy clusters in RCS-1: spectroscopic confirmation, redshift accuracy, and dynamical mass-richness relation

    Science.gov (United States)

    Gilbank, David G.; Barrientos, L. Felipe; Ellingson, Erica; Blindert, Kris; Yee, H. K. C.; Anguita, T.; Gladders, M. D.; Hall, P. B.; Hertling, G.; Infante, L.; Yan, R.; Carrasco, M.; Garcia-Vergara, Cristina; Dawson, K. S.; Lidman, C.; Morokuma, T.

    2018-05-01

    We present follow-up spectroscopic observations of galaxy clusters from the first Red-sequence Cluster Survey (RCS-1). This work focuses on two samples, a lower redshift sample of ˜30 clusters ranging in redshift from z ˜ 0.2-0.6 observed with multiobject spectroscopy (MOS) on 4-6.5-m class telescopes and a z ˜ 1 sample of ˜10 clusters 8-m class telescope observations. We examine the detection efficiency and redshift accuracy of the now widely used red-sequence technique for selecting clusters via overdensities of red-sequence galaxies. Using both these data and extended samples including previously published RCS-1 spectroscopy and spectroscopic redshifts from SDSS, we find that the red-sequence redshift using simple two-filter cluster photometric redshifts is accurate to σz ≈ 0.035(1 + z) in RCS-1. This accuracy can potentially be improved with better survey photometric calibration. For the lower redshift sample, ˜5 per cent of clusters show some (minor) contamination from secondary systems with the same red-sequence intruding into the measurement aperture of the original cluster. At z ˜ 1, the rate rises to ˜20 per cent. Approximately ten per cent of projections are expected to be serious, where the two components contribute significant numbers of their red-sequence galaxies to another cluster. Finally, we present a preliminary study of the mass-richness calibration using velocity dispersions to probe the dynamical masses of the clusters. We find a relation broadly consistent with that seen in the local universe from the WINGS sample at z ˜ 0.05.

  18. Morphological and functional rescue in RCS rats after RPE cell line transplantation at a later stage of degeneration.

    Science.gov (United States)

    Wang, Shaomei; Lu, Bin; Girman, Sergej; Holmes, Toby; Bischoff, Nicolas; Lund, Raymond D

    2008-01-01

    It is well documented that grafting of cells in the subretinal space of Royal College of Surgeons (RCS) rats limits deterioration of vision and loss of photoreceptors if performed early in postnatal life. What is unclear is whether cells introduced later, when photoreceptor degeneration is already advanced, can still be effective. This possibility was examined in the present study, using the human retinal pigment epithelial cell line, ARPE-19. Dystrophic RCS rats (postnatal day [P] 60) received subretinal injection of ARPE-19 cells (2 x 10(5)/3 microL/eye). Spatial frequency was measured by recording optomotor responses at P100 and P150, and luminance threshold responses were recorded from the superior colliculus at P150. Retinas were stained with cresyl violet, retinal cell-specific markers, and a human nuclear marker. Control animals were injected with medium alone. Animals comparably treated with grafts at P21 were available for comparison. All animals were treated with immunosuppression. Later grafts preserved both spatial frequency and threshold responses over the control and delayed photoreceptor degeneration. There were two to three layers of rescued photoreceptors even at P150, compared with a scattered single layer in sham and untreated control retinas. Retinal cell marker staining showed an orderly array of the inner retinal lamination. The morphology of the second-order neurons was better preserved around the grafted area than in regions distant from graft. Sham injection had little effect in rescuing the photoreceptors. RPE cell line transplants delivered later in the course of degeneration can preserve not only the photoreceptors and inner retinal lamination but also visual function in RCS rats. However, early intervention can achieve better rescue.

  19. A microRNA, mir133b, suppresses melanopsin expression mediated by failure dopaminergic amacrine cells in RCS rats.

    Science.gov (United States)

    Li, Yaochen; Li, Chunshi; Chen, Zhongshan; He, Jianrong; Tao, Zui; Yin, Zheng Qin

    2012-03-01

    The photopigment melanopsin and melanopsin-containing RGCs (mRGCs or ipRGCs) represent a brand-new and exciting direction in the field of visual field. Although the melanopsin is much less sensitive to light and has far less spatial resolution, mRGCs have the unique ability to project to brain areas by the retinohypothalamic tract (RHT) and communicate directly with the brain. Unfortunately, melanopsin presents lower expression levels in many acute and chronic retinal diseases. The molecular mechanisms underlying melanopsin expression are not yet really understood. MicroRNAs play important roles in the control of development. Most importantly, the link of microRNA biology to a diverse set of cellular processes, ranging from proliferation, apoptosis and malignant transformation to neuronal development and fate specification is emerging. We employed Royal College of Surgeon (RCS) rats as animal model to investigate the underlying molecular mechanism regulating melanopsin expression using a panel of miRNA by quantitative real-time reverse transcription polymerase chain reaction. We identified a microRNA, mir133b, that is specifically expressed in retinal dopaminergic amacrine cells as well as markedly increased expression at early stage during retinal degeneration in RCS rats. The overexpression of mir133b downregulates the important transcription factor Pitx3 expression in dopaminergic amacrine cells in RCS rats retinas and makes amacrine cells stratification deficit in IPL. Furthermore, deficient dopaminergic amacrine cells presented decreased TH expression and dopamine production, which lead to a failure to direct mRGCs dendrite to stratify and enter INL and lead to the reduced correct connections between amacrine cells and mRGCs. Our study suggested that overexpression of mir133b and downregulated Pitx3 suppress maturation and function of dopaminergic amacrine cells, and overexpression of mir133b decreased TH and D2 receptor expression as well as dopamine

  20. Proposal for a national synchrotron light source

    International Nuclear Information System (INIS)

    Blewett, J.P.

    1977-02-01

    Since 1971 discussions have been held at Brookhaven National Laboratory on the desirability of construction of a storage ring which would be used exclusively for production of intense beams of photons with wavelengths in the ultraviolet and X-ray ranges. A proposal is given which discusses in detail the machine, its characteristics, and its expected uses. The proposal includes: (1) characteristics of synchrotron radiation; (2) scientific justification for a synchrotron radiation facility; (3) facility design; (4) wiggler magnets; (5) experimental facilities; (6) buildings and utilities; (7) construction schedules, costs, and manpower; and (8) environmental assessment

  1. Challenges and opportunities in synchrotron radiation optics

    Science.gov (United States)

    Rehn, V.

    Design necessities germaine to advances in optics for experimentation with synchrotron radiation are explored. Objectives for development include improved beam-line performance using new mirror materials or coatings, filtering and order-sorting enhancement, and lower surface scattering. A summary is presented of optical systems currently in use, together with requirements imposed by storage rings and experimental design. Advances are recommended in intensity, collimation, focus, and spectral purity of synchrotron beam lines. Any new storage ring mirror is noted to be required to dissipate several hundred watts, something which polished Cu is mentioned as being capable of handling, while standard SiO2 mirrors cannot.

  2. Atomic collision experiments using pulsed synchrotron radiation

    International Nuclear Information System (INIS)

    Arikawa, Tatsuo; Watanabe, Tsutomu.

    1982-01-01

    High intensity and continuous nature of the synchrotron radiation are the properties that are fundamentally important for studies of some atomic collision experiments, and many processes have been investigated by using these characteristics. However, so far the property that the radiation is highly polarized and pulsed in time has not been exploited significantly in atomic physics. As an example of the atomic processes relevant to such polarized and pulsed features of the synchrotron radiation, collisions involving optically-allowed excited atoms and molecules will be presented. (author)

  3. 12 Experimental Techniques at Synchrotron Lightsource Beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Peter L [US Department of Energy Office of Science Office Basic Energy Sciences; Rhyne, James J [US Department of Energy Office of Science Office of Basic Energy Sciences

    2015-01-01

    The unique properties of synchrotron radiation are its continuous spectrum, high flux and brightness, and high coherence, which make it an indispensable tool in the exploration of matter. The wavelengths of the emitted photons span a range of dimensions from the atomic level to biological cells, thereby providing incisive probes for advanced research in materials science, physical and chemical sciences, metrology, geosciences, environmental sciences, biosciences, medical sciences, and pharmaceutical sciences. The features of synchrotron radiation are especially well matched to the needs of nanoscience.

  4. RF control system of the HIMAC synchrotron

    International Nuclear Information System (INIS)

    Kanazawa, M.; Sato, K.; Itano, A.

    1992-01-01

    An RF control system of the HIMAC synchrotron has been constructed. In this control system we have adopted a digital feed back system with a digital synthesizer (DS). Combining a high power system, performance of the control system have been tested in a factory (Toshiba) with a simulator circuit of the synchrotron oscillation. Following this test, We had beam acceleration test with this control system at TARN-II in INS (Institute for Nuclear Study, University of Tokyo). This paper describes the RF control system and its tested results. (author)

  5. Automation and Remote Synchrotron Data Collection

    International Nuclear Information System (INIS)

    Gilski, M.

    2008-01-01

    X-ray crystallography is the natural choice for macromolecular structure determination by virtue of its accuracy, speed, and potential for further speed gains, while synchrotron radiation is indispensable because of its intensity and tuneability. Good X-ray crystallographic diffraction patterns are essential and frequently this is achievable through using the few large synchrotrons located worldwide. Beamline time on these facilities have long queues, and increasing the efficiency of utilization of these facilities will help in expediting the structure determination process. Automation and remote data collection are therefore essential steps in ensuring that macromolecular structure determination becomes a very high throughput process. (author)

  6. Bunch heating by coherent synchrotron radiation

    International Nuclear Information System (INIS)

    Heifets, S.A.; Zolotorev, M.

    1995-10-01

    The authors discuss here effects which define the steady-state rms energy spread of a microbunch in a storage ring. It is implied that the longitudinal microwave instability is controlled by low α lattice. In this case the coherent synchrotron radiation, if exists, may be the main factor defining the bunch temperature. Another effect comes from the fact that a nonlinear momentum compaction of such lattices makes Haissinskii equation not applicable, and the coherent synchrotron radiation may effect not only bunch lengthening but the energy spread as well

  7. Technique of infrared synchrotron acceleration diagnostics

    International Nuclear Information System (INIS)

    Mal'tsev, A.A.; Mal'tsev, M.A.

    1997-01-01

    Techniques of measuring of current and geometric parameters and evaluating of energy parameters of the ring bunch of relativistic low-energy electrons have been presented. They have been based on using the synchrotron radiation effect in its infrared spectral part. Fast infrared detectors have provided radiation detection in the spectral range Δλ ≅ 0.3-45 μm. The descriptions of some data monitoring and measuring systems developed in JINR for the realization of techniques of the infrared synchrotron acceleration diagnostics have been given. Infrared optics elements specially developed have been used in these systems

  8. Development of Probability Evaluation Methodology for High Pressure/Temperature Gas Induced RCS Boundary Failure and SG Creep Rupture

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Chul; Hong, Soon Joon; Lee, Jin Yong; Lee, Kyung Jin; Lee, Kuh Hyung [FNC Tech. Co., Seoul (Korea, Republic of)

    2008-04-15

    Existing MELCOR 1.8.5 model was improved in view of severe accident natural circulation and MELCOR 1.8.6 input model was developed and calculation sheets for detailed MELCOR 1.8.6 model were produced. Effects of natural circulation modeling were found by simulating SBO accident by comparing existing model with detailed model. Major phenomenon and system operations which affect on natural circulation by high temperature and high pressure gas were investigated and representative accident sequences for creep rupture model of RCS pipeline and SG tube were selected.

  9. Preliminar plan of a machine for the synchrotron radiation production

    International Nuclear Information System (INIS)

    Moscati, G.; Takahashi, J.; Miyao, Y.

    1985-01-01

    A preliminar plan, with all the technical specifications, for the construction of a machine for the synchrotron radiation production to be done by the National Synchrotron Radiation Laboratory in Brazil is presented. (L.C.) [pt

  10. What is a synchrotron and why does Australia need one?

    CERN Document Server

    Nugent, K A

    2002-01-01

    Construction of a $157 million synchrotron will soon begin in Melbourne. The author describes what this facility means for Australian science. The Australian synchrotron is a third generation device. The facility would have the capacity to do a wide range of science and technology at the same time. A number of applications, which are the priority for the Australian synchrotron project are briefly described. The huge technological spin-offs of this knowledge have made synchrotrons an attractive proposition to state governments

  11. Synchrotron radiation and free electron laser activities in Novosibirsk

    International Nuclear Information System (INIS)

    Korchuganov, V.N.; Kulipanov, G.N.; Mezentsev, N.A.; Oreshkov, A.D.; Panchenko, V.E.; Pindyurin, V.F.; Skrinskij, A.N.; Sheromov, M.A.; Vinokurov, N.A.; Zolotarev, K.V.

    1994-01-01

    The results of studies realized in the Siberian synchrotron radiation centre within the frameworks of wide program of synchrotron radiation and free electron laser research are summarized. The technical information on the VEPP-2M, VEPP-3 and VEPP-4M storage rings used as synchrotron radiation sources is given. 10 refs.; 8 figs.; 12 tabs

  12. Coherence Inherent in an Incoherent Synchrotron Radio Source ...

    Indian Academy of Sciences (India)

    It is well known that synchrotron radiation mechanism does not allow MASER type coherent emission (Pacholczyk 1970). Here we show that coherence can naturally occur in a synchrotron ... cally thick region (Fig. 1), then divides the synchrotron spectrum into an incoherent. 1A thin flat circular unleavened Indian bread.

  13. Photonuclear physics at the Bonn synchrotrons. Present status and future plans at the Bonn synchrotron

    International Nuclear Information System (INIS)

    Mecking, B.A.

    1983-11-01

    The activities in the field of photonuclear physics at the Bonn 500 MeV and 2.5 GeV synchrotrons are reviewed. The experiments concentrate on photodisintegration and pion-photoproduction reactions on light nuclei. (orig.)

  14. Wellcome Trust backs Rutherford to host synchrotron

    CERN Document Server

    Leder, N

    1999-01-01

    The Wellcome Trust has stated its preference for the site of the new Anglo-French synchrotron to be at RAL in Oxfordshire. But the statement coincides with an announcement from the UK government that a decision on the location of 'Diamond' will be delayed to allow two new reports on the canditate sites to be commissioned (1/2 page).

  15. Atomic physics research with synchrotron radiation

    International Nuclear Information System (INIS)

    Crasemann, B.

    1981-01-01

    Applications of synchrotron radiation to research in high-energy atomic physics are summarized. These lie in the areas of photoelectron spectrometry, photon scattering, x-ray absorption spectroscopy, time-resolved measurements, resonance spectroscopy and threshold excitation, and future, yet undefined studies

  16. Nuclear Bragg diffraction using synchrotron radiation

    International Nuclear Information System (INIS)

    Rueffer, R.; Gerdau, E.; Grote, M.; Hollatz, R.; Roehlsberger, R.; Rueter, H.D.; Sturhahn, W.

    1990-01-01

    Nuclear Bragg diffraction with synchrotron radiation as source will become a powerful new X-ray source in the A-region. This source exceeds by now the brilliance of conventional Moessbauer sources giving hyperfine spectroscopy further momentum. As examples applications to yttrium iron garnet (YIG) and iron borate will be discussed. (author)

  17. Reflectometry with synchrotron radiation; Reflektometrie mit Synchrotronstrahlung

    Energy Technology Data Exchange (ETDEWEB)

    Krumrey, Michael [Physikalisch-Technische Bundesanstalt (PTB), Berlin (Germany). Arbeitsgruppe ' Roentgenradiometrie' ; Cibik, Levent; Fischer, Andreas; Gottwald, Alexander; Kroth, Udo; Scholze, Frank

    2014-09-15

    The measurement of the reflectivity for VUV, XUV, and X-radiation at the PTB synchrotron radiation sources is described. The corresponding data of the used beams are presented. Results of experiments on a Cu-Ni double-layer, SiO{sub 2}, Si, and MgF{sub 2} are presented. (HSI)

  18. Internal magnetic target of proton synchrotron

    International Nuclear Information System (INIS)

    Gachurin, V.V.; Kats, M.M.; Kondrat'ev, L.N.; Rogal', A.D.; Rusinov, V.Yu.

    1988-01-01

    Proton extraction from a synchrotron by means of an internal target of magnetized iron is described. The particles that are aimed at the target pass directly through it and are deflected by the internal magnetic field of the target in the extraction direction. The general properties of magnetic targets are examined theoretically and a specific devices and results of its testing are described

  19. HIDE working groups: synchrotron based system: summary

    International Nuclear Information System (INIS)

    Barton, M.Q.

    1978-01-01

    A brief overview is given of the work resulting from a one-week workshop on the use of synchrotrons in heavy ion fusion, i.e., a Heavy Ion Demonstration Experiment (HIDE). Topics discussed concerned the number of beams on target, space charge limitations, choice of ion charge state, and areas identified as needing further work

  20. Overview of United States synchrotron radiation facilities

    International Nuclear Information System (INIS)

    Watson, R.E.

    1983-01-01

    There has been considerable activity within the past year involving the creation of new and the improvement of existing capabilities for research with synchrotron light. The purpose of this review is to summarize what has happened within the United States. Being a status report, some of the information necessarily has a date attached to it - the date, in this case, being early September 1983

  1. HIDE working groups. A. Synchrotron based system

    International Nuclear Information System (INIS)

    Barton, M.Q.

    1977-01-01

    A summary is given of a week's discussions on an ion source to target scenario for a synchrotron for heavy ion fusion. Topics considered include: the number of beams on the target; beam dynamics; and a number of areas explicitly identified as needing further work

  2. Materials science and technology by synchrotron radiation

    International Nuclear Information System (INIS)

    Chikawa, J.

    1990-01-01

    In the present paper, features of the Photon Factory, a facility for synchrotron research installed at the National Laboratory for High Energy Physics in Japan, are outlined, and then the impact of the advent of synchrotron radiation is discussed in relation to its outcome during the past seven years. Prospects for future development of synchrotron radiation are also presented. The facility consists of an injector linac to accelerate electrons up to 2.5 GeV and a ring to store the accelerated electrons in a closed orbit. In the Photon Factory, a 400m-long linac has been constructed for use as injector for both the Photon Factory and the TRISTAN electron-positron collider. The storage ring is operated at the same electron energy of 2.5 GeV. The present report also describes some applications of synchrotron radiation, focusing on spectroscopy (X-ray fluorescence technique and time-resolved X-ray absorption spectroscopy), diffraction and scattering (surface structure studies and protein crystallography), and photo-chemical processing. (N.K.)

  3. Studies on the role of molybdenum on iodine transport in the RCS in nuclear severe accident conditions

    International Nuclear Information System (INIS)

    Grégoire, A.-C.; Kalilainen, J.; Cousin, F.; Mutelle, H.; Cantrel, L.; Auvinen, A.; Haste, T.; Sobanska, S.

    2015-01-01

    Highlights: • In oxidising conditions, Mo reacts with Cs and thus promotes gaseous iodine release. • In reducing conditions, CsI remains the dominant form for released iodine. • The nature of released iodine is well reproduced by the ASTEC code. - Abstract: The effect of molybdenum on iodine transport in the reactor coolant system (RCS) under PWR severe accident conditions was investigated in the framework of the EU SARNET project. Experiments were conducted at the VTT-Institute and at IRSN and simulations of the experimental results were performed with the ASTEC severe accident simulation code. As molybdenum affects caesium chemistry by formation of molybdates, it may have a significant impact on iodine transport in the RCS. Experimentally it has been shown that the formation of gaseous iodine is promoted in oxidising conditions, as caesium can be completely consumed to form caesium polymolybdates and is thus not available for reacting with gaseous iodine and leading to CsI aerosols. In reducing conditions, CsI remains the dominant form of iodine, as the amount of oxygen is not sufficient to allow formation of quantitative caesium polymolybdates. An I–Mo–Cs model has been developed and it reproduces well the experimental trends on iodine transport

  4. The Quantitative Reasoning for College Science (QuaRCS) Assessment: Emerging Themes from 5 Years of Data

    Science.gov (United States)

    Follette, Katherine; Dokter, Erin; Buxner, Sanlyn

    2018-01-01

    The Quantitative Reasoning for College Science (QuaRCS) Assessment is a validated assessment instrument that was designed to measure changes in students' quantitative reasoning skills, attitudes toward mathematics, and ability to accurately assess their own quantitative abilities. It has been administered to more than 5,000 students at a variety of institutions at the start and end of a semester of general education college science instruction. I will begin by briefly summarizing our published work surrounding validation of the instrument and identification of underlying attitudinal factors (composite variables identified via factor analysis) that predict 50% of the variation in students' scores on the assessment. I will then discuss more recent unpublished work, including: (1) Development and validation of an abbreviated version of the assessment (The QuaRCS Light), which results in marked improvements in students' ability to maintain a high effort level throughout the assessment and has broad implications for quantitative reasoning assessments in general, and (2) Our efforts to revise the attitudinal portion of the assessment to better assess math anxiety level, another key factor in student performance on numerical assessments.

  5. The profile of the electron beam in the PTB synchrotron, and its influence on radiometric measurements with synchrotron radiation

    International Nuclear Information System (INIS)

    Kaase, H.

    1976-01-01

    A simple method is described to determine the beam profile in an electron synchrotron; the measured results are compared with calculated values. Moreover, the influence of synchrotron- and betatron-oscillations on synchrotron radiation measurements is discussed, and a method is given to correct this. (orig.) [de

  6. 50 years of synchrotrons. Early synchrotrons in Britain, and early work for CERN. - The CERN synchrotrons. Lectures

    International Nuclear Information System (INIS)

    Lawson, J.; Brianti, G.

    1997-01-01

    In the first report, 'Early synchrotrons in Britain, and early work for CERN', John Lawson gives an extended account of the material presented at the John Adams lecture, and at the same time a revised and shortened version of RAL report 97-011, which contains fuller archival references and notes. During the period covered by this report there was extensive work in Russia, where the principle of phase stability had been discovered in 1944 by Veksler. Unfortunately, all experimental work was kept secret until Veksler's talk at the first 'Atoms for Peace' conference at Geneva in August 1955. In the second lecture, 'The CERN Synchrotrons', Giorgio Brianti outlines the history of alternating-gradient synchrotrons from 1953/54 until today. In preparing this lecture he was confronted with a vast amount of material, while the time at his disposal was not even one minute per year, implying a time compression factor close to one million. Therefore, he had to exercise drastic choices, which led him to concentrate on CERN hadron synchrotrons and colliders and leave aside the Large Electron-Positron storage ring (LEP). Indeed, LEP was the subject of the John Adams Memorial Lecture in 1990, and it may be treated again in the future in connection with its energy upgrade. Even with these severe limitations, it was impossible to do justice to the number and variety of events and to the ingenuity of the people who have carved the history of CERN and of particle physics on the magnets, radiofrequency cavities, vacuum etc., and on the record performance of our machines. (orig./WL)

  7. Control Loops for the J-PARC RCS Digital Low-Level RF Control

    CERN Document Server

    Schnase, Alexander; Ezura, Eizi; Hara, Keigo; Nomura, Masahiro; Ohmori, Chihiro; Takagi, Akira; Tamura, Fumihiko; Yamamoto, Masanobu; Yoshii, Masahito

    2005-01-01

    The low-level radiofrequency control for the Rapic Cycling Synchrotron of J-PARC is based on digital signal processing. This system controls the acceleration voltages of 12 magnetic alloy loaded cavities. To achive a short overall delay, mandatory for stable loop operation, the data-processing is based on distributed arithmetics in FPGA. Due to the broadband characteristic of the acceleration cavities, no tuning loop is needed. To handle the large beam current, the RF system operates simultaneously with dual harmonics (h=2) and (h=4). The stability of the amplitude loops is limited by the delay of the FIR filters used after downconversion. The phase loop offers several operation modes to define the phase relation of (h=2) and (h=4) between the longitudinal beam signal and the vector-sum of the cavity voltages. Besides the FIR filters, we provide cascaded CIC filters with smoothly varying coefficients. Such a filter tracks the revolution frequency and has a substantially shorter delay, thereby increasing the s...

  8. Ideas for future synchrotron light sources

    International Nuclear Information System (INIS)

    Jackson, A.; Hassenzahl, W.; Meddahi, M.

    1992-03-01

    Synchrotron light sources have advanced in the past two-to-three decades through three ''generations,'' from irritating parasitic sources on high-energy physics accelerators to dedicated electron and position storage rings of unprecedented low emittance, utilizing undulator and wiggler magnets. The evolution through these three generations followed a predicable, science-driven, course towards brighter beams of VUV- and x-radiation. The requirements of future light sources is not so clear. The limit on how emittance has certainly not been reached, and diffraction-limited sources at shorter wavelengths would be the natural progression from previous generations. However, scientists are now looking at other radiation characteristics that might better serve their needs, for example, more coherent power, fast switching polarization, ultra-short (sub-picosecond) time structure, and synchronized beams for pump-probe experiments. This paper discusses some current ideas that might drive the fourth-generation synchrotron light source

  9. Applications of Indus-1 synchrotron radiation source

    International Nuclear Information System (INIS)

    Nandedkar, R.V.

    2003-01-01

    Indus-1 is a 450 MeV electron storage ring. This is a soft X-ray and Vacuum Ultra Violet radiation source with the critical wavelength being 61 A. In this source, the first beam was stored in mid-1999 and was then made available, after initial storage and beam cleaning of the vacuum components, for beamline installation in the early 2000. Two beamlines are commissioned and are working. Other beamlines are in the advanced stage of commissioning. For Indus-1, the injection system consists of a 20 MeV classical microtron as a preinjector and a booster synchrotron that can go up to 700 MeV. For Indus-1, the injection into the storage ring is at full 450 MeV from this booster synchrotron

  10. The 400 GeV proton synchrotron

    International Nuclear Information System (INIS)

    1976-05-01

    A general account is given of the 400-GeV proton synchrotron, known as Super Proton Synchrotron (SPS), of the European Organization for Nuclear Research (CERN) at Geneva. A brief chapter on the history of the project covers the steps leading to the earlier plan for a 300-GeV accelerator at a new CERN laboratory elsewhere in Europe, abandoned in 1971 in favour of the present machine, and the progress of construction of the latter. The general features of the SPS design are outlined, illustrated by an aerial view of the CERN site, a plan of the SPS, and interior views of the SPS ring tunnel and main control room. (WSN)

  11. Materials science created by synchrotron radiation

    International Nuclear Information System (INIS)

    Oshima, Masaharu

    2015-01-01

    We survey the use of synchrotron radiation for studies on oxides. High luminosity enables the spectroscopy with high energy-resolution in soft X-ray and vacuum ultraviolet region. Element analysis is possible by examining absorption edge in the X-ray absorption spectra. Time-resolved measurements are possible due to the pulsed nature of the radiation. The radiation can bear linear or circular polarization. The feature of molecules adhered on a surface can be clarified by using linearly polarized radiation. The circularly polarized radiation, on the other hand, clarifies the magnetic structure. The structure information so far unknown can be obtained by using space- or time-coherent radiation. We show studies using synchrotron radiation on LSI gate oxide foils, variable resistance RAM, strongly correlated oxide foils, and the oxide as positive electrode of Li ion battery. (J.P.N.)

  12. The relativistic foundations of synchrotron radiation.

    Science.gov (United States)

    Margaritondo, Giorgio; Rafelski, Johann

    2017-07-01

    Special relativity (SR) determines the properties of synchrotron radiation, but the corresponding mechanisms are frequently misunderstood. Time dilation is often invoked among the causes, whereas its role would violate the principles of SR. Here it is shown that the correct explanation of the synchrotron radiation properties is provided by a combination of the Doppler shift, not dependent on time dilation effects, contrary to a common belief, and of the Lorentz transformation into the particle reference frame of the electromagnetic field of the emission-inducing device, also with no contribution from time dilation. Concluding, the reader is reminded that much, if not all, of our argument has been available since the inception of SR, a research discipline of its own standing.

  13. Propagation of synchrotron radiation through nanocapillary structures

    International Nuclear Information System (INIS)

    Bjeoumikhov, A.; Bjeoumikhova, S.; Riesemeier, H.; Radtke, M.; Wedell, R.

    2007-01-01

    The propagation of synchrotron radiation through nanocapillary structures with channel sizes of 200 nm and periods in the micrometer size has been studied experimentally. It was shown that the propagation through individual capillary channels has a mode formation character. Furthermore it was shown that during the propagation through capillary channels the coherence of synchrotron radiation is partially conserved. Interference of beams propagating through different capillary channels is observed which leads to a periodically modulated distribution of the radiation intensity in a plane far from the exit of the structure. These investigations are of high relevance for the understanding of X-ray transmission through nanocapillaries and the appearance of wave properties at this size scale

  14. Synchrotron Applications of High Magnetic Fields

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This workshop aims at discussing the scientific potential of X-ray diffraction and spectroscopy in magnetic fields above 30 T. Pulsed magnetic fields in the range of 30 to 40 T have recently become available at Spring-8 and the ESRF (European synchrotron radiation facility). This document gathers the transparencies of the 6 following presentations: 1) pulsed magnetic fields at ESRF: first results; 2) X-ray spectroscopy and diffraction experiments by using mini-coils: applications to valence state transition and frustrated magnet; 3) R{sub 5}(Si{sub x}Ge{sub 1-x}){sub 4}: an ideal system to be studied in X-ray under high magnetic field?; 4) high field studies at the Advanced Photon Source: present status and future plans; 5) synchrotron X-ray diffraction studies under extreme conditions; and 6) projects for pulsed and steady high magnetic fields at the ESRF.

  15. ANKA - new horizons with synchrotron radiation

    International Nuclear Information System (INIS)

    Hagelstein, M.; Czolk, R.

    2001-01-01

    ANKA GmbH operates a state-of-the-art electron storage ring (2.5 GeV energy, 400 mA maximum current) for the production of high-intensity synchrotron radiation. The produced 'superlight' ranges from the hard X-ray to the infrared region of the electromagnetic spectrum. To use the light for microfabrication and analysis a number of modern, high quality production and experimental facilities exist on this circular (diameter about 35 m) synchrotron radiation sources. The experimental facilities are consolidated by a young, experienced and highly motivated team of experts. For the patterning of polymers by deep X-ray lithography three end-stations (so-called beamlines) are available. For analytical tasks five beamlines are established where different experiments can be made based on X-ray methods such as X-ray absorption, diffraction and fluorescence spectroscopy as well as IR-spectroscopy. (orig.)

  16. Synchrotron radiation. Basics, methods and applications

    International Nuclear Information System (INIS)

    Mobilio, Settimio; Meneghini, Carlo; Boscherini, Federico

    2015-01-01

    Synchrotron radiation is today extensively used for fundamental and applied research in many different fields of science. Its exceptional characteristics in terms of intensity, brilliance, spectral range, time structure and now also coherence pushed many experimental techniques to previously un-reachable limits, enabling the performance of experiments unbelievable only few years ago. The book gives an up-to-date overview of synchrotron radiation research today with a view to the future, starting from its generation and sources, its interaction with matter, illustrating the main experimental technique employed and provides an overview of the main fields of research in which new and innovative results are obtained. The book is addressed to PhD students and young researchers to provide both an introductory and a rather deep knowledge of the field. It will also be helpful to experienced researcher who want to approach the field in a professional way.

  17. Single-mode coherent synchrotron radiation instability

    Directory of Open Access Journals (Sweden)

    S. Heifets

    2003-06-01

    Full Text Available The microwave instability driven by the coherent synchrotron radiation (CSR has been previously studied [S. Heifets and G. V. Stupakov, Phys. Rev. ST Accel. Beams 5, 054402 (2002] neglecting effect of the shielding caused by the finite beam pipe aperture. In practice, the unstable mode can be close to the shielding threshold where the spectrum of the radiation in a toroidal beam pipe is discrete. In this paper, the CSR instability is studied in the case when it is driven by a single synchronous mode. A system of equations for the beam-wave interaction is derived and its similarity to the 1D free-electron laser theory is demonstrated. In the linear regime, the growth rate of the instability is obtained and a transition to the case of continuous spectrum is discussed. The nonlinear evolution of the single-mode instability, both with and without synchrotron damping and quantum diffusion, is also studied.

  18. In-flight measurements and RCS-predictions: A comparison on broad-side radar range profiles of a Boeing 737

    NARCIS (Netherlands)

    Heiden, R. van der; Ewijk, L.J. van; Groen, F.C.A.

    1997-01-01

    The validation of Radar Cross Section (RCS) prediction techniques against real measurements is crucial to acquire confidence in predictions when measurements are not available. In this paper we present the first results of a comparison on one dimensional images, i.e., radar range profiles. The

  19. Raman lidar measurements of water vapor and aerosols during the atmospheric radiation measurement (ARM) remote clouds sensing (RCS) intensive observation period (IOP)

    Energy Technology Data Exchange (ETDEWEB)

    Melfi, S.H.; Starr, D.O`C.; Whiteman, D. [NASA Goddard Space Flight Center, Greenbelt, MD (United States)] [and others

    1996-04-01

    The first Atmospheric Radiation Measurement (ARM) remote Cloud Study (RCS) Intensive Operations Period (IOP) was held during April 1994 at the Southern Great Plains (SGP) site. This experiment was conducted to evaluate and calibrate state-of-the-art, ground based remote sensing instruments and to use the data acquired by these instruments to validate retrieval algorithms developed under the ARM program.

  20. Structural analysis with high brilliance synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Ohno, Hideo [Japan Atomic Energy Research Inst., Kamigori, Hyogo (Japan). Kansai Research Establishment

    1997-11-01

    The research subjects in diffraction and scattering of materials with high brilliance synchrotron radiation such as SPring-8 (Super Photon ring 8 GeV) are summarized. The SPring-8 project is going well and 10 public beamlines will be opened for all users in October, 1997. Three JAERI beamlines are also under construction for researches of heavy element science, physical and structural properties under extreme conditions such as high temperature and high pressure. (author)

  1. The Australian synchrotron - a progress report

    International Nuclear Information System (INIS)

    Boldeman, J.; Jackson, A.; Seaborne, G.; Hobbs, R.; Garrett, R.

    2003-01-01

    This paper summarises progress with the development of the Australian Synchrotron. The facility is based on the Boomerang Storage Ring which has a DBA structure with 14 superperiods. The design objective was to achieve a low emittance in a relatively compact circumference that had an excellent dynamic aperture and was obust with respect to potential construction aberrations. The potential suite of beamline and instrument stations is discussed and some examples are given

  2. Trace element measurements with synchrotron radiation

    International Nuclear Information System (INIS)

    Hanson, A.L.; Kraner, H.W.; Jones, K.W.; Gordon, B.M.; Mills, R.E.

    1982-01-01

    Aspects of the application of synchrotron radiation to trace element determinations by x-ray fluorescence have been investigated using beams from the Cornell facility, CHESS. Fluoresced x rays were detected with a Si(Li) detector placed 4 cm from the target at 90 0 to the beam. Thick samples of NBS Standard Reference Materials were used to calibrate trace element sensitivity and estimate minimum detectable limits for this method

  3. Plasma diagnostics using synchrotron radiation in tokamaks

    International Nuclear Information System (INIS)

    Fidone, I.; Giruzzi, G.; Granata, G.

    1995-09-01

    This report deal with the use of synchrotron radiation in tokamaks. The main advantage of this new method is that it enables to overcome several deficiencies, caused by cut-off, refraction, and harmonic overlap. It also makes it possible to enhance the informative contents of the familiar low harmonic scheme. The basic theory of the method is presented and illustrated by numerical applications, for plasma parameters of relevance in present and next step tokamaks. (TEC). 10 refs., 13 figs

  4. Synchrotron radiation sources in the Soviet Union

    International Nuclear Information System (INIS)

    Kapitza, S.P.

    1987-01-01

    Synchrotron radiation (SR) is now recognized to be an important instrument for experimental work in many fields of science. Recently the application of SR in medicine and industry, especially as a light source for microelectronics production have been demonstrated. Thus the development of SR sources has now grown to become a significant and independent dimension for accelerator research and technology. This article describes SR work in the Soviet Union

  5. Review of beamloading and compensation in synchrotrons

    International Nuclear Information System (INIS)

    Koscielniak, S.

    2001-10-01

    This paper discusses the theory and state-of-the-art applications of beam loading and compensation in synchrotrons. In particular it discusses the developments in the introduction of Magnetic Alloy (e.g. Finemet) cores and adoption of low Q cavities; e plus-e minus factories with very large current (e.g. KEKB, PEP II) and developments at p,p factories (e.g. LHC) and simulation codes

  6. Synchrotron radiation: its characteristics and applications

    International Nuclear Information System (INIS)

    Blewett, J.P.; Chasman, R.; Green, G.K.

    1977-01-01

    It has been known for a century that charged particles radiate when accelerated and that relativistic electrons in the energy range between 100 MeV and several GeV and constrained to travel in circular orbits emit concentrated, intense beams with broad continuous spectra that can cover the electromagnetic spectrum from infrared through hard X-rays. Recently the possible applications of this radiation have been appreciated and electron synchrotrons and electron storage rings are now being used in many centers for studies of the properties of matter in the solid, liquid and gaseous states. A brief history is presented of ''synchrotron radiation'' as it is now called. The basic properties of this radiation are described and the world-wide distribution is indicated of facilities for its production. Particular attention is given to the proposed facility at Brookhaven which will be the first major installation to be dedicated only to the production and use of synchrotron radiation. Finally, typical examples are given of applications in the areas of radiation absorption studies, techniques based on scattering of radiation, and advances based on X-ray lithography

  7. Tabletop synchrotron and its unique features

    CERN Document Server

    Yamada, H

    2002-01-01

    Two synchrotrons, AURORA and MIRRORCLE, were built in Ritsumeikan University. MIRRORCLE-20 is the smallest normal conduction synchrotron (15 cm orbit radius and 1.2 m outer diameter) in the world. It uses 2/3 resonance method for electron beam incidence but is not optimized for X-ray generation. MIRRORCLE-6 shall be optimized for X-ray generation. X-ray generated by MIRRORCLE shows very flat white light, rich in hard X-ray, pulse with width changeable from a few mu s to a few ms , wide radiation angle of 25 mrad at MIRRORCLE-20 and 80 mrad at MIRRORCLE-8 and high coherence. The feature such as pulsed light and high coherence is expected to new application which photon radiation cannot practice. Imaging experiments by MIRRORCLE were carried out by Cu plate, Al plate, Teflon and acryl plate. We took a photograph of insect, electric lamp, connector, and cyclotron. New X-ray generation mechanism, X-ray strength, development of tabletop synchrotron and features of X-ray beam are explained. (S.Y.)

  8. Paraxial Green's functions in synchrotron radiation theory

    International Nuclear Information System (INIS)

    Geloni, G.; Saldin, E.; Scheidmiller, E.; Yurkov, M.

    2005-02-01

    This work contains a systematic treatment of single particle synchrotron radiation and some application to realistic beams with given cross section area, divergence and energy spread. Standard theory relies on several approximations whose applicability limits and accuracy are often forgotten. We begin remarking that on the one hand, a paraxial approximation can always be applied without loss of generality and with ultra relativistic accuracy. On the other hand, dominance of the acceleration field over the velocity part in the Lienard-Wiechert expressions is not always guaranteed and constitutes a separate assumption, whose applicability is discussed. Treating synchrotron radiation in paraxial approximation we derive the equation for the slow varying envelope function of the Fourier components of the electric field vector. Calculations of Synchrotron Radiation properties performed by others showed that the phase of the Fourier components of the electric field vector differs from the phase of a virtual point source. In this paper we present a systematic, analytical description of this phase shift, calculating amplitude and phase of electric field from bending magnets, short magnets, two bending magnet system separated by a straight section (edge radiation) and undulator devices. We pay particular attention to region of applicability and accuracy of approximations used. Finally, taking advantage of results of analytical calculation presented in reduced form we analyze various features of radiation from a complex insertion device (set of two undulators with a focusing triplet in between) accounting for the influence of energy spread and electron beam emittance. (orig.)

  9. MICROANALYSIS OF MATERIALS USING SYNCHROTRON RADIATION.

    Energy Technology Data Exchange (ETDEWEB)

    JONES,K.W.; FENG,H.

    2000-12-01

    High intensity synchrotron radiation produces photons with wavelengths that extend from the infrared to hard x rays with energies of hundreds of keV with uniquely high photon intensities that can be used to determine the composition and properties of materials using a variety of techniques. Most of these techniques represent extensions of earlier work performed with ordinary tube-type x-ray sources. The properties of the synchrotron source such as the continuous range of energy, high degree of photon polarization, pulsed beams, and photon flux many orders of magnitude higher than from x-ray tubes have made possible major advances in the possible chemical applications. We describe here ways that materials analyses can be made using the high intensity beams for measurements with small beam sizes and/or high detection sensitivity. The relevant characteristics of synchrotron x-ray sources are briefly summarized to give an idea of the x-ray parameters to be exploited. The experimental techniques considered include x-ray fluorescence, absorption, and diffraction. Examples of typical experimental apparatus used in these experiments are considered together with descriptions of actual applications.

  10. Photoemission studies using laboratory and synchrotron sources

    International Nuclear Information System (INIS)

    Phase, D.M.

    2012-01-01

    Synchrotron radiation sources, providing intense, polarized and stable beams of ultra violet soft and hard X-ray photons, are having great impact on physics, chemistry, biology materials science and other areas research. In particular synchrotron radiation has revolutionized photoelectron spectroscopy by enhancing its capabilities for investigating the electronic properties of solids. The first Indian synchrotron storage ring, Indus- 1 is in operation at RRCAT, Indore. The UGC-DAE CSR with the help of university scientist had designed and developed an angle integrated photoelectron spectroscopy (PES) beamline on this 450 MeV storage ring. A storage ring of this kind is most suitable for investigation in the energy range from few electron volts to around five hundred electron volts. In this lecture we will describe the details of PES beamline and its experimental station. Till date the different university users carried out photoemission measurements on variety of samples. Some of the spectra recorded by users will be presented in order to show the capability of this beamline. In the later part we will report a review of our recent research work carried out on dilute magnetic thin films using this beamline. (author)

  11. 50 Years of synchrotrons Adams' Memorial lecture

    CERN Document Server

    Lawson, J D; CERN. Geneva

    1996-01-01

    Fifty years ago Frank Goward of the Atomic Energy Research Establishment Group at Malvern converted a small American betatron to make the worldÕs first synchrotron. At the same time Marcus Oliphant was planning to build at Birmingham a large proton machine with a ring magnet and variable magnetic field. Ideas for this had come to him during night-shifts tending the electromagnetic separators at Oak Ridge during the war. Some seven years later, in 1953, a group gathered together in Geneva to build the PS. A major contributor to the design work which had made this possible was John Adams. An account of some of the achievements in these eventful years will be presented. CERN has built nine synchrotrons/colliders and two temporary test rings. Eight machines are still running. The review will start with the PS, the first proton synchrotron based on the alternating gradient principle invented in 1952 at BNL. The design work of the PS team, under the enlightened leadership of J.B. Adams, and the construction of the...

  12. Ultrafast molecular dynamics illuminated with synchrotron radiation

    International Nuclear Information System (INIS)

    Bozek, John D.; Miron, Catalin

    2015-01-01

    Highlights: • Ultrafast molecular dynamics probed with synchrotron radiation. • Core-excitation as probe of ultrafast dynamics through core-hole lifetime. • Review of experimental and theoretical methods in ultrafast dynamics using core-level excitation. - Abstract: Synchrotron radiation is a powerful tool for studying molecular dynamics in small molecules in spite of the absence of natural matching between the X-ray pulse duration and the time scale of nuclear motion. Promoting core level electrons to unoccupied molecular orbitals simultaneously initiates two ultrafast processes, nuclear dynamics on the potential energy surfaces of the highly excited neutral intermediate state of the molecule on the one hand and an ultrafast electronic decay of the intermediate excited state to a cationic final state, characterized by a core hole lifetime. The similar time scales of these processes enable core excited pump-probe-type experiments to be performed with long duration X-ray pulses from a synchrotron source. Recent results obtained at the PLIEADES beamline concerning ultrafast dissociation of core excited states and molecular potential energy curve mapping facilitated by changes in the geometry of the short-lived intermediate core excited state are reviewed. High brightness X-ray beams combined with state-of-the art electron and ion-electron coincidence spectrometers and highly sophisticated theoretical methods are required to conduct these experiments and to achieve a full understanding of the experimental results.

  13. Tabletop synchrotron and its unique features

    International Nuclear Information System (INIS)

    Yamada, Hironari

    2002-01-01

    Two synchrotrons, AURORA and MIRRORCLE, were built in Ritsumeikan University. MIRRORCLE-20 is the smallest normal conduction synchrotron (15 cm orbit radius and 1.2 m outer diameter) in the world. It uses 2/3 resonance method for electron beam incidence but is not optimized for X-ray generation. MIRRORCLE-6 shall be optimized for X-ray generation. X-ray generated by MIRRORCLE shows very flat white light, rich in hard X-ray, pulse with width changeable from a few μs to a few ms , wide radiation angle of 25 mrad at MIRRORCLE-20 and 80 mrad at MIRRORCLE-8 and high coherence. The feature such as pulsed light and high coherence is expected to new application which photon radiation cannot practice. Imaging experiments by MIRRORCLE were carried out by Cu plate, Al plate, Teflon and acryl plate. We took a photograph of insect, electric lamp, connector, and cyclotron. New X-ray generation mechanism, X-ray strength, development of tabletop synchrotron and features of X-ray beam are explained. (S.Y.)

  14. Synchrotron-radiation experiments with recoil ions

    International Nuclear Information System (INIS)

    Levin, J.C.

    1989-01-01

    Studies of atoms, ions and molecules with synchrotron radiation have generally focused on measurements of properties of the electrons ejected during, or after, the photoionization process. Much can also be learned, however, about the atomic or molecular relaxation process by studies of the residual ions or molecular fragments following inner-shell photoionization. Measurements are reported of mean kinetic energies of highly charged argon, krypton, and xenon recoil ions produced by vacancy cascades following inner-shell photoionization using white and monochromatic synchrotron x radiation. Energies are much lower than for the same charge-state ions produced by charged-particle impact. The results may be applicable to design of future angle-resolved ion-atom collision experiments. Photoion charge distributions are presented and compared with other measurements and calculations. Related experiments with synchrotron-radiation produced recoil ion, including photoionization of stored ions and measurement of shakeoff in near-threshold excitation, are briefly discussed. 24 refs., 6 figs., 1 tab

  15. Overview and perspective of materials characterization by using synchrotron radiation

    International Nuclear Information System (INIS)

    Kamitsubo, Hiromichi

    2009-01-01

    A peculiarity of techniques and the methods of synchrotron radiation are explained. It consists of five sections such as introduction, synchrotron radiation, interaction between X-ray and materials, analytical methods of materials using synchrotron radiation and perspective and problems. The second section described the principles of synchrotron orbit radiation, synchrotron light source, the main formulae and schematic drawing of undulator, and the synchrotron radiation facilities in Japan. The third section explained behavior of X-ray in materials, absorption, reflection, refraction and scattering of X-ray. The fourth section stated many analytical methods of materials; the surface diffractometer, powder diffractometer, high-energy X-ray diffraction, core-electron absorption spectroscopy, micro-beam diffraction, X-ray fluorescence, X-ray absorption fine structure (XAFS), and photoemission spectroscopy (PES). A characteristic feature of synchrotron radiation contains the large wave length ranges from infrared to X-ray, high directivity and brightness, linear (circular) polarization, pulsed light, good control and stability. The brightness spectra of Spring-8 and SAGA-LS, concept of synchrotron light source, undulator and wiggler, nine synchrotron radiation facilities in Japan, mass absorption coefficients of Cu and Au, and analysis of materials using synchrotron radiation are illustrated. (S.Y.)

  16. Transparent Gap Filler Solution over a DVB-RCS2 Satellite Platform in a Railway Scenario: Performance Evaluation Study

    Directory of Open Access Journals (Sweden)

    Peppino Fazio

    2015-01-01

    Full Text Available In this work, a performance study of a system equipped with a transparent Gap Filler solution in a DVB-RCS2 satellite platform has been provided. In particular, a simulation model based on a 3-state Markov chain, overcoming the blockage status through the introduction of a transparent Gap Filler (using devices on both tunnel sides has been implemented. The handover time, due to switching mechanism between satellite and Gap Filler, has been taken into account. As reference scenario, the railway market has been considered, which is characterized by a N-LOS condition, due to service disruptions caused by tunnels, vegetation and buildings. The system performance, in terms of end-to-end delay, queue size and packet loss percentage, have been evaluated, in order to prove the goodness of communications in a real railroad path.

  17. Effect of injection energy on residual dose around the charge exchange foil

    Directory of Open Access Journals (Sweden)

    Kazami Yamamoto

    2012-12-01

    Full Text Available The rapid cycling synchrotron (RCS of Japan Proton Accelerator Research Complex (J-PARC and the accumulator ring (AR of Spallation Neutron Source (SNS can be used as high-power pulsed neutron sources. In both cases, the injection region becomes one of the highest activation areas in the ring. However, residual dose distributions have revealed that the highest activation points in the J-PARC RCS and the SNS AR are different in detail. The dose of the charge exchange chamber in the SNS is more than 100 times larger than that of the RCS though the ratio of beam power is less than 10. We investigated the reason of this difference by Geant4 and MARS, and the calculation results indicated that the difference was due to the dependence of the neutron and pion production rate on the injection energy.

  18. Serratia marcescens ShlA pore-forming toxin is responsible for early induction of autophagy in host cells and is transcriptionally regulated by RcsB.

    Science.gov (United States)

    Di Venanzio, Gisela; Stepanenko, Tatiana M; García Véscovi, Eleonora

    2014-09-01

    Serratia marcescens is a Gram-negative bacterium that thrives in a wide variety of ambient niches and interacts with an ample range of hosts. As an opportunistic human pathogen, it has increased its clinical incidence in recent years, being responsible for life-threatening nosocomial infections. S. marcescens produces numerous exoproteins with toxic effects, including the ShlA pore-forming toxin, which has been catalogued as its most potent cytotoxin. However, the regulatory mechanisms that govern ShlA expression, as well as its action toward the host, have remained unclear. We have shown that S. marcescens elicits an autophagic response in host nonphagocytic cells. In this work, we determine that the expression of ShlA is responsible for the autophagic response that is promoted prior to bacterial internalization in epithelial cells. We show that a strain unable to express ShlA is no longer able to induce this autophagic mechanism, while heterologous expression of ShlA/ShlB suffices to confer on noninvasive Escherichia coli the capacity to trigger autophagy. We also demonstrate that shlBA harbors a binding motif for the RcsB regulator in its promoter region. RcsB-dependent control of shlBA constitutes a feed-forward regulatory mechanism that allows interplay with flagellar-biogenesis regulation. At the top of the circuit, activated RcsB downregulates expression of flagella by binding to the flhDC promoter region, preventing FliA-activated transcription of shlBA. Simultaneously, RcsB interaction within the shlBA promoter represses ShlA expression. This circuit offers multiple access points to fine-tune ShlA production. These findings also strengthen the case for an RcsB role in orchestrating the expression of Serratia virulence factors. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  19. National Synchrotron Light Source: vacuum system for National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Schuchman, J.C.; Godel, J.B.; Jordan, W.; Oversluizen, T.

    1978-01-01

    The National Synchrotron Light Source (NSLS), a 24 million dollar project under construction at Brookhaven National Laboratory (BNL), is a research facility dedicated to the production of synchrotron radiation. Synchrotron radiation is that radiation produced by the acceleration of charged particles at near the speed of light. This facility will provide a continuous spectrum of radiation from the vacuum ultraviolet to the hard x-ray range. The radiation will be highly intense, 100% polarized, extremely well collimated and will have a pulsed time structure. The radiation will be produced in two electron storage rings at energies of 700 MeV and 2.5 GeV, respectively. A maximum of one ampere at 2 GeV, or one-half ampere at 2.5 GeV, of electron beam will be stored

  20. Alterations of sodium and potassium channels of RGCs in RCS rat with the development of retinal degeneration.

    Science.gov (United States)

    Chen, Zhongshan; Song, Yanping; Yao, Junping; Weng, Chuanhuang; Yin, Zheng Qin

    2013-11-01

    All know that retinitis pigmentosa (RP) is a group of hereditary retinal degenerative diseases characterized by progressive dysfunction of photoreceptors and associated with progressive cells loss; nevertheless, little is known about how rods and cones loss affects the surviving inner retinal neurons and networks. Retinal ganglion cells (RGCs) process and convey visual information from retina to visual centers in the brain. The healthy various ion channels determine the normal reception and projection of visual signals from RGCs. Previous work on the Royal College of Surgeons (RCS) rat, as a kind of classical RP animal model, indicated that, at late stages of retinal degeneration in RCS rat, RGCs were also morphologically and functionally affected. Here, retrograde labeling for RGCs with Fluorogold was performed to investigate the distribution, density, and morphological changes of RGCs during retinal degeneration. Then, patch clamp recording, western blot, and immunofluorescence staining were performed to study the channels of sodium and potassium properties of RGCs, so as to explore the molecular and proteinic basis for understanding the alterations of RGCs membrane properties and firing functions. We found that the resting membrane potential, input resistance, and capacitance of RGCs changed significantly at the late stage of retinal degeneration. Action potential could not be evoked in a part of RGCs. Inward sodium current and outward potassium current recording showed that sodium current was impaired severely but only slightly in potassium current. Expressions of sodium channel protein were impaired dramatically at the late stage of retinal degeneration. The results suggested that the density of RGCs decreased, process ramification impaired, and sodium ion channel proteins destructed, which led to the impairment of electrophysiological functions of RGCs and eventually resulted in the loss of visual function.

  1. Distribution of Synthetic Cannabinoids JWH-210, RCS-4 and Δ 9-Tetrahydrocannabinol After Intravenous Administration to Pigs.

    Science.gov (United States)

    Schaefer, Nadine; Kettner, Mattias; Laschke, Matthias W; Schlote, Julia; Ewald, Andreas H; Menger, Michael D; Maurer, Hans H; Schmidt, Peter H

    2017-01-01

    Synthetic cannabinoids (SCs) have become an increasing issue in forensic toxicology. Controlled human studies evaluating pharmacokinetic data of SCs are lacking and only few animal studies have been published. Thus, an interpretation of analytical results found in intoxicated or poisoned individuals is difficult. Therefore, the distribution of two selected SCs, namely 4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-210) and 2-(4-methoxyphenyl)-1-(1- pentyl-indol-3-yl)methanone (RCS-4) as well as Δ9-tetrahydrocannabinol (THC) as reference were examined in pigs. Pigs (n = 6 per drug) received a single intravenous 200 μg/kg BW dose of JWH-210, RCS- 4, or THC. Six hours after administration, the animals were exsanguinated and relevant organs, important body fluids such as bile, and tissues such as muscle and adipose tissue, as well as the bradytrophic specimens dura and vitreous humor were collected. After hydrolysis and solid phase extraction, analysis was performed by LC-MS/MS. To overcome matrix effects of the LC-MS/MS analysis, a standard addition method was applied for quantification. The parent compounds could be detected in every analyzed specimen with the exception of THC that was not present in dura and vitreous humor. Moderate concentrations were present in brain, the site of biological effect. Metabolite concentrations were highest in tissues involved in metabolism and/or elimination Conclusions: Besides kidneys and lungs routinely analyzed in postmortem toxicology, brain, adipose, and muscle tissue could serve as alternative sources, particularly if other specimens are not available. Bile fluid is the most appropriate specimen for SCs and THC metabolites detection. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  2. Distribution of Synthetic Cannabinoids JWH-210, RCS-4 and ∆ 9-Tetrahydrocannabinol After Intravenous Administration to Pigs

    Science.gov (United States)

    Schaefer, Nadine; Kettner, Mattias; Laschke, Matthias W.; Schlote, Julia; Ewald, Andreas H.; Menger, Michael D.; Maurer, Hans H.; Schmidt, Peter H.

    2017-01-01

    Background: Synthetic cannabinoids (SCs) have become an increasing issue in forensic toxicology. Controlled human studies evaluating pharmacokinetic data of SCs are lacking and only few animal studies have been published. Thus, an interpretation of analytical results found in intoxicated or poisoned individuals is difficult. Therefore, the distribution of two selected SCs, namely 4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-210) and 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone (RCS-4) as well as ∆9-tetrahydrocannabinol (THC) as reference were examined in pigs. Methods: Pigs (n = 6 per drug) received a single intravenous 200 µg/kg BW dose of JWH-210, RCS-4, or THC. Six hours after administration, the animals were exsanguinated and relevant organs, important body fluids such as bile, and tissues such as muscle and adipose tissue, as well as the bradytrophic specimens dura and vitreous humor were collected. After hydrolysis and solid phase extraction, analysis was performed by LC-MS/MS. To overcome matrix effects of the LC-MS/MS analysis, a standard addition method was applied for quantification. Results: The parent compounds could be detected in every analyzed specimen with the exception of THC that was not present in dura and vitreous humor. Moderate concentrations were present in brain, the site of biological effect. Metabolite concentrations were highest in tissues involved in metabolism and/or elimination. Conclusions: Besides kidneys and lungs routinely analyzed in postmortem toxicology, brain, adipose, and muscle tissue could serve as alternative sources, particularly if other specimens are not available. Bile fluid is the most appropriate specimen for SCs and THC metabolites detection. PMID:27834143

  3. Relativistic Turbulence with Strong Synchrotron and Synchrotron-Self-Compton Cooling

    Science.gov (United States)

    Uzdensky, D. A.

    2018-03-01

    Many relativistic plasma environments in high-energy astrophysics, including pulsar wind nebulae, hot accretion flows onto black holes, relativistic jets in active galactic nuclei and gamma-ray bursts, and giant radio lobes, are naturally turbulent. The plasma in these environments is often so hot that synchrotron and inverse-Compton (IC) radiative cooling becomes important. In this paper we investigate the general thermodynamic and radiative properties (and hence the observational appearance) of an optically thin relativistically hot plasma stirred by driven magnetohydrodynamic (MHD) turbulence and cooled by radiation. We find that if the system reaches a statistical equilibrium where turbulent heating is balanced by radiative cooling, the effective electron temperature tends to attain a universal value θ = kT_e/m_e c^2 ˜ 1/√{τ_T}, where τT = neσTL ≪ 1 is the system's Thomson optical depth, essentially independent of the strength of turbulent driving and hence of the magnetic field. This is because both MHD turbulent dissipation and synchrotron cooling are proportional to the magnetic energy density. We also find that synchrotron self-Compton (SSC) cooling and perhaps a few higher-order IC components are automatically comparable to synchrotron in this regime. The overall broadband radiation spectrum then consists of several distinct components (synchrotron, SSC, etc.), well separated in photon energy (by a factor ˜ τ_T^{-1}) and roughly equal in power. The number of IC peaks is checked by Klein-Nishina effects and depends logarithmically on τT and the magnetic field. We also examine the limitations due to synchrotron self-absorption, explore applications to Crab PWN and blazar jets, and discuss links to radiative magnetic reconnection.

  4. New synchrotron radiation facility project. Panel on new synchrotron radiation facility project

    CERN Document Server

    Sato, S; Kimura, Y

    2003-01-01

    The project for constructing a new synchrotron radiation facility dedicated to the science in VUV (or EUV) and Soft X-ray (SX) region has been discussed for these two years at the Panel on New Synchrotron Radiation Facility Project. The Panel together with the Accelerator Design Working Group (WG), Beamline Design WG and Research Program WG suggested to the Ministry of Education, Science, Culture and Sports the construction of a 1.8 GeV electron storage ring suitable for 'Top-Up' operation and beamlines and monochromators designed for undulator radiation. The scientific programs proposed by nationwide scientists are summarized with their requirements of the characteristics of the beam. (author)

  5. PERFORMANCE ANALYSIS OF MULTI-TURN EXTRACTION FROM THE PROTON SYNCHROTRON TO THE SUPER PROTON SYNCHROTRON

    CERN Document Server

    Abernethy, Samuel

    2016-01-01

    Within CERN's accelerator complex, the extraction from the Proton Synchrotron to the Super Proton Synchrotron has been done using the so-called ``Continuous Transfer" (CT) method since the 1970's. A new technique, known as Multi-Turn Extraction (MTE), has now been implemented and is in full operation. This report examines a holistic performance analysis of the novel technique in multiple aspects of the accelerator complex, as well as a direct comparison with its predecessor, CT, from the implementation of MTE in 2010 until the end of 2015.

  6. Around the laboratories: Dubna: Physics results and progress on bubble chamber techniques; Stanford (SLAC): Operation of a very rapid cycling bubble chamber; Daresbury: Photographs of visitors to the Laboratory; Argonne: Charge exchange injection tests into the ZGS in preparation for a proposed Booster

    CERN Multimedia

    1969-01-01

    Around the laboratories: Dubna: Physics results and progress on bubble chamber techniques; Stanford (SLAC): Operation of a very rapid cycling bubble chamber; Daresbury: Photographs of visitors to the Laboratory; Argonne: Charge exchange injection tests into the ZGS in preparation for a proposed Booster

  7. CHESS-the Cornell High Energy Synchrotron Source

    International Nuclear Information System (INIS)

    Batterman, B.W.; Cornell Univ., Ithaca, NY

    1980-01-01

    The Wilson Laboratory at Cornell University has done pioneering work on development of high energy synchrotrons. In the last decade, the 12 GeV synchrotron has been the most energetic electron synchrotron in the world. In 1975 plans were formulated to build a 4-8 GeV storage ring in the same tunnel as the synchrotron and to use the latter as the injector for the storage ring. This small radius (the normal bend magnets have R = 87 m), coupled with the relatively high electron energy of the storage ring, makes these magnets potent sources of synchrotron radiation. In June of 1978 the National Science Foundation funded a project to create CHESS, the Cornell High Energy Synchrotron Source. (orig./FKS)

  8. Historical development of synchrotron x-ray diffraction topography

    International Nuclear Information System (INIS)

    Kawado, Seiji

    2011-01-01

    After a short history of X-ray diffraction topography, from the early stage of laboratory X-ray topography to recent synchrotron-radiation applications, is described, the development of science and technology for the synchrotron X-ray topography and its industrial applications are reviewed in more detail. In addition, the recent trend to synchrotron topography research is clarified on the basis of several data obtained from 256 papers which have been published since 2000. (author)

  9. Techniques for materials research with synchrotron radiation x-rays

    International Nuclear Information System (INIS)

    Bowen, D.K.

    1983-01-01

    A brief introductory survey is presented of the properties and generation of synchrotron radiation and the main techniques developed so far for its application to materials problems. Headings are:synchrotron radiation; X-ray techniques in synchrotron radiation (powder diffraction; X-ray scattering; EXAFS (Extended X-ray Absorption Fine Structure); X-ray fluorescent analysis; microradiography; white radiation topography; double crystal topography); future developments. (U.K.)

  10. Atomic photoelectron-spectroscopy studies using synchrotron radiation

    International Nuclear Information System (INIS)

    Kobrin, P.H.

    1983-02-01

    Photoelectron spectroscopy combined with tunable synchrotron radiation has been used to study the photoionization process in several atomic systems. The time structure of the synchrotron radiation source at the Stanford Synchrotron Radiation Laboratory (SSRL) was used to record time-of-flight (TOF) photoelectron spectra of gaseous Cd, Hg, Ne, Ar, Ba, and Mn. The use of two TOF analyzers made possible the measurement of photoelectron angular distributions as well as branching ratios and partial cross sections

  11. Planning study for advanced national synchrotron-radiation facilities

    International Nuclear Information System (INIS)

    1984-01-01

    A new generation of synchrotron-radiation sources based on insertion devices offers gains in photon-beam brilliance as large as the gains that present-day synchrotron sources provided over conventional sources. This revolution in synchrotron capability and its impact on science and technology will be as significant as the original introduction of synchrotron radiation. This report recommends that insertion-device technology be pursued as our highest priority, both through the full development of insertion-device potential on existing machines and through the building of new facilities

  12. SOFT: a synthetic synchrotron diagnostic for runaway electrons

    Science.gov (United States)

    Hoppe, M.; Embréus, O.; Tinguely, R. A.; Granetz, R. S.; Stahl, A.; Fülöp, T.

    2018-02-01

    Improved understanding of the dynamics of runaway electrons can be obtained by measurement and interpretation of their synchrotron radiation emission. Models for synchrotron radiation emitted by relativistic electrons are well established, but the question of how various geometric effects—such as magnetic field inhomogeneity and camera placement—influence the synchrotron measurements and their interpretation remains open. In this paper we address this issue by simulating synchrotron images and spectra using the new synthetic synchrotron diagnostic tool SOFT (Synchrotron-detecting Orbit Following Toolkit). We identify the key parameters influencing the synchrotron radiation spot and present scans in those parameters. Using a runaway electron distribution function obtained by Fokker-Planck simulations for parameters from an Alcator C-Mod discharge, we demonstrate that the corresponding synchrotron image is well-reproduced by SOFT simulations, and we explain how it can be understood in terms of the parameter scans. Geometric effects are shown to significantly influence the synchrotron spectrum, and we show that inherent inconsistencies in a simple emission model (i.e. not modeling detection) can lead to incorrect interpretation of the images.

  13. Bystander Effects During Synchrotron Imaging Procedures?

    International Nuclear Information System (INIS)

    Schueltke, Elisabeth; Nikkhah, Guido; Bewer, Brian; Wysokinski, Tomasz; Chapman, Dean

    2010-01-01

    Using monochromatic beam and synchrotron phase-contrast technique at the biomedical beamline of the Italian synchrotron facility Elettra (SYRMEP), we have shown in a small animal model of malignant brain tumor that it is possible to obtain high-resolution images of very small tumors when they have developed from implanted tumor cells loaded with colloidal gold nanoparticles (GNP). All previous experiments were conducted in post-mortem samples. We have now designed a cell culture experiment to investigate the effects of synchrotron radiation with an energy and dose profile similar to that expected in our first in vivo imaging studies according to the protocol developed at SYRMEP.Materials and Methods: Culture flasks containing either gold-loaded or naieve C6 glioma cells were exposed to a dose of 0.5 Gy at 24 keV. The irradiated medium was aspirated and replaced with fresh growth medium. Twenty-four hours later this non-irradiated medium exposed to irradiated cells was aspirated, then added to non-irradiated C6 cells in order to investigate whether bystander effects are seen under the conditions of our image acquisition protocol. The irradiated medium was added to a number of other non-irradiated cell cultures. Cell counts were followed until 72 hrs after irradiation. Western blots were conducted with H2AX antibodies. This experiment was one of the first biomedical experiments conducted at BMIT, the new biomedical imaging and therapy beamline of the Canadian Light Source.Results: No significant differences in proliferation were seen between cells that were directly irradiated, exposed to irradiated medium or exposed to the non-irradiated 24-hr-medium from the irradiated cells. However, there was a tendency towards a higher number of double strand breaks in previously irradiated cells when they were exposed to non-irradiated medium that had been in contact with irradiated cells for 24 hrs.

  14. Handbook on synchrotron radiation, v.2

    CERN Document Server

    1987-01-01

    Volume 2 of this series concentrates on the use of synchrotron radiation which covers that region of the electromagnetic spectrum which extends from about 10eV to 3keV in photon energy and is essentially the region where the radiation is strongly absorbed by atmospheric gases. It therefore has to make extensive use of a high vacuum to transport the radiation to the workstation where the presence of hard X-rays can cause extensive damage to both the optics and the targets used in the experimental rigs. The topics chosen for this volume have been limited to the disciplines of physics and chemi

  15. Bent approximations to synchrotron radiation optics

    International Nuclear Information System (INIS)

    Heald, S.

    1981-01-01

    Ideal optical elements can be approximated by bending flats or cylinders. This paper considers the applications of these approximate optics to synchrotron radiation. Analytic and raytracing studies are used to compare their optical performance with the corresponding ideal elements. It is found that for many applications the performance is adequate, with the additional advantages of lower cost and greater flexibility. Particular emphasis is placed on obtaining the practical limitations on the use of the approximate elements in typical beamline configurations. Also considered are the possibilities for approximating very long length mirrors using segmented mirrors

  16. Atomic electron spectrometry with synchrotron radiation

    International Nuclear Information System (INIS)

    Sorensen, S.L.

    1989-01-01

    Techniques of atomic electron spectrometry were applied to atoms in the gaseous and solid states to derive information about fundamental atomic properties. A new method was developed to measure Coster-Kronig yields in metals by photoionization with synchrotron radiation. Photon-energy sensitive Si L-VV Auger satellites were investigated via electron spectrometry. The krypton 1s photoionization spectrum was measured in an experiment which was motivated by the need to understand the krypton 1s satellite spectrum for calibration of an experiment to measure the mass of the electron antineutrino

  17. Effective spectrum width of the synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Bagrov, V. G., E-mail: bagrov@phys.tsu.ru [Department of Physics, Tomsk State University, Tomsk (Russian Federation); Institute of High Current Electronics, SB RAS, Tomsk (Russian Federation); Gitman, D. M., E-mail: gitman@if.usp.br [Department of Physics, Tomsk State University, Tomsk (Russian Federation); Institute of Physics, University of São Paulo, São Paulo (Brazil); P.N.Lebedev Physical Institute, Moscow (Russian Federation); Levin, A. D., E-mail: alevin@if.usp.br [Institute of Physics, University of São Paulo, São Paulo (Brazil); Loginov, A. S.; Saprykin, A. D. [Department of Physics, Tomsk State University, Tomsk (Russian Federation)

    2015-11-25

    For an exact quantitative description of spectral properties of synchrotron radiation (SR), the concept of effective width of the spectrum is introduced. In the most interesting case, which corresponds to the ultrarelativistic limit of SR, the effective width of the spectrum is calculated for the polarization components, and new physically important quantitative information on the structure of spectral distributions is obtained. For the first time, the spectral distribution for the circular polarization component of the SR for the upper half-space is obtained within classical theory.

  18. Effective spectrum width of the synchrotron radiation

    International Nuclear Information System (INIS)

    Bagrov, V. G.; Gitman, D. M.; Levin, A. D.; Loginov, A. S.; Saprykin, A. D.

    2015-01-01

    For an exact quantitative description of spectral properties of synchrotron radiation (SR), the concept of effective width of the spectrum is introduced. In the most interesting case, which corresponds to the ultrarelativistic limit of SR, the effective width of the spectrum is calculated for the polarization components, and new physically important quantitative information on the structure of spectral distributions is obtained. For the first time, the spectral distribution for the circular polarization component of the SR for the upper half-space is obtained within classical theory

  19. Effective spectrum width of the synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Bagrov, V.G. [Tomsk State University, Department of Physics, Tomsk (Russian Federation); SB RAS, Institute of High Current Electronics, Tomsk (Russian Federation); Gitman, D.M. [Tomsk State University, Department of Physics, Tomsk (Russian Federation); University of Sao Paulo, Institute of Physics, Sao Paulo (Brazil); P.N. Lebedev Physical Institute, Moscow (Russian Federation); Levin, A.D. [University of Sao Paulo, Institute of Physics, Sao Paulo (Brazil); Loginov, A.S.; Saprykin, A.D. [Tomsk State University, Department of Physics, Tomsk (Russian Federation)

    2015-11-15

    For an exact quantitative description of spectral properties of synchrotron radiation (SR), the concept of effective width of the spectrum is introduced. In the most interesting case, which corresponds to the ultrarelativistic limit of SR, the effective width of the spectrum is calculated for the polarization components, and new physically important quantitative information on the structure of spectral distributions is obtained. For the first time, the spectral distribution for the circular polarization component of the SR for the upper half-space is obtained within classical theory. (orig.)

  20. Scanning photoemission microscopy with synchrotron radiation

    Science.gov (United States)

    Ade, Harald W.

    1992-08-01

    Progress in photoemission spectro-microscopy at various synchrotron radiation facilities is reviewed. Microprobe devices such as MAXIMUM at the SRC in Wisconsin, the X1-SPEM at the NSLS at BNL, as well as the ellipsoidal ring mirror microscope at DESY in Hamburg, recorded first images during the last few years. The present status of these devices which achieve their lateral resolution by focusing X-rays to a small spot is the primary focus of this paper, but work representing other approaches to spectro-microscopy is also discussed.

  1. Synchrotron-radiation plane-wave topography

    International Nuclear Information System (INIS)

    Riglet, P.; Sauvage, M.; Petroff, J.F.; Epelboin, Y.

    1980-01-01

    A computer program based on the Takagi-Taupin differential equations for X-ray propagation in distorted crystals has been developed in order to simulate dislocation images in the Bragg case. The program is valid both for thin and thick crystals. Simulated images of misfit dislocations formed either in a thin epilayer or in a thick substrate are compared with experimental images obtained by synchrotron-radiation plane-wave topography. The influence of the various strain components on the image features is discussed. (author)

  2. Femto-second pulses of synchrotron radiation

    International Nuclear Information System (INIS)

    Zholents, A.A.; Zolotorev, M.S.

    1995-07-01

    A method capable of producing femto-second pulses of synchrotron radiation is proposed. It is based on the interaction of femto-second light pulses with electrons in a storage ring. The application of the method to the generation of ultra-short x-ray pulses at the Advance Light Source of Lawrence Berkeley National Laboratory has been considered. The same method can also be used for extraction of electrons from a storage ring in ultra-short series of microbunches spaced by the periodicity of light wavelength

  3. Glancing angle synchrotron X-ray diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Cernik, R J [Daresbury Lab., Warrington, WA (United States)

    1996-09-01

    This paper describes in basic detail some of the techniques that can be used to study thin films and surfaces. These are all in the X-ray region and cover reflectivity, diffraction form polycrystalline films, textured films and single crystal films. Other effects such as fluorescence and diffuse scattering are mentioned but not discussed in detail. Two examples of the reflectivity from multilayers and the diffraction from iron oxide films are discussed. The advantages of the synchrotron for these studies is stressed and the experimental geometries that can be employed are described i detail. A brief bibliography is provided at the end to accompany this part of the 1996 Frascati school.

  4. Variable-Period Undulators for Synchrotron Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Shenoy, Gopal; Lewellen, John; Shu, Deming; Vinokurov, Nikolai

    2005-02-22

    A new and improved undulator design is provided that enables a variable period length for the production of synchrotron radiation from both medium-energy and high energy storage rings. The variable period length is achieved using a staggered array of pole pieces made up of high permeability material, permanent magnet material, or an electromagnetic structure. The pole pieces are separated by a variable width space. The sum of the variable width space and the pole width would therefore define the period of the undulator. Features and advantages of the invention include broad photon energy tunability, constant power operation and constant brilliance operation.

  5. Medical applications of synchrotron radiation. Ch. 10

    International Nuclear Information System (INIS)

    Giacomini, J.C.; Gordon, H.J.

    1991-01-01

    Synchrotron radiation has a number of properties which make it uniquely suited for medical diagnostic imaging. The radiation is intense and can be readily monochromatized. With these highly intense, mono-chromatized X-ray beams, iodine K-edge di-chromatography can yield images which greatly enhance the visualization of iodine containing structures. As this technology continues to improve, the possibility of performing diagnostic cardiac, neuroradiological, and other vascular examinations with minimally invasive peripheral venous injections of iodinated contrast agent becomes increasingly practical. (author). 10 refs.; 6 figs

  6. Coherent Synchrotron Radiation in Storage Rings

    International Nuclear Information System (INIS)

    Venturini, Marco

    2002-01-01

    We take a detour from the main theme of this volume and present a discussion of coherent synchrotron radiation (CSR) in the context of storage rings rather than single-pass systems. Interest in this topic has been revived by a series of measurements carried out at several light source facilities. There is strong evidence that the observed coherent signal is accompanied by a beam instability, possibly driven by CSR itself. In this paper we review a ''self-consistent'' model of longitudinal beam dynamics in which CSR is the only agent of collective forces. The model yields numerical solutions that appear to reproduce the main features of the observations

  7. Variable-Period Undulators For Synchrotron Radiation

    Science.gov (United States)

    Shenoy, Gopal; Lewellen, John; Shu, Deming; Vinokurov, Nikolai

    2005-02-22

    A new and improved undulator design is provided that enables a variable period length for the production of synchrotron radiation from both medium-energy and high-energy storage rings. The variable period length is achieved using a staggered array of pole pieces made up of high permeability material, permanent magnet material, or an electromagnetic structure. The pole pieces are separated by a variable width space. The sum of the variable width space and the pole width would therefore define the period of the undulator. Features and advantages of the invention include broad photon energy tunability, constant power operation and constant brilliance operation.

  8. 3D IMAGING USING COHERENT SYNCHROTRON RADIATION

    Directory of Open Access Journals (Sweden)

    Peter Cloetens

    2011-05-01

    Full Text Available Three dimensional imaging is becoming a standard tool for medical, scientific and industrial applications. The use of modem synchrotron radiation sources for monochromatic beam micro-tomography provides several new features. Along with enhanced signal-to-noise ratio and improved spatial resolution, these include the possibility of quantitative measurements, the easy incorporation of special sample environment devices for in-situ experiments, and a simple implementation of phase imaging. These 3D approaches overcome some of the limitations of 2D measurements. They require new tools for image analysis.

  9. Coherent reflectivity using white synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Panzner, Tobias; Sant, Tushar; Pietsch, Ullrich [Universitaet Siegen (Germany). Festkoerperphysik

    2008-07-01

    Using coherent white synchrotron radiation in the hard X-ray region for reflectivity experiments one have access to sample properties on a nanometer scale in principle. To extract the wanted information from the performed measurements so called phase retrieval algorithms are necessary. The authors developed a straight forward simulation program based on a spatial limited atomic flat surface to evaluate the influence of different parameters on the coherent scattered signal in the detector plane. These simulations can explain some interesting features of the measurements and shows unexpected results for the influence of the so called illumination function.

  10. Microangiography in Living Mice Using Synchrotron Radiation

    International Nuclear Information System (INIS)

    Yuan Falei; Wang Yongting; Xie Bohua; Tang Yaohui; Guan Yongjing; Lu Haiyan; Yang Guoyuan; Xie Honglan; Du Guohao; Xiao Tiqiao

    2010-01-01

    Traditionally, there are no methods available to detect the fine morphologic changes of cerebrovasculature in small living animals such as rats and mice. Newly developed synchrotron radiation microangiography can achieve a fine resolution of several micrometers and had provided us with a powerful tool to study the cerebral vasculature in small animals. The purpose of this study is to identify the morphology of cerebrovasculature especially the structure of Lenticulostriate arteries (LSAs) in living mice using the synchrotron radiation source at Shanghai Synchrotron Radiation Facility (SSRF) in Shanghai, China. Adult CD-1 mice weighing 35-40 grams were anesthetized. Nonionic iodine (Omnipaque, 350 mg I /mL) was used as a contrast agent. The study was performed at the BL13W1 beam line at SSRF. The beam line was derived from a storage ring of electrons with an accelerated energy of 3.5 GeV and an average beam current of 200 mA. X-ray energy of 33.3 keV was used to produce the highest contrast image. Images were acquired every 172 ms by a x-ray camera (Photonic-Science VHR 1.38) with a resolution of 13 μm/pixel. The optimal dose of contrast agent is 100 μl per injection and the injecting rate is 33 μl/sec. The best position for imaging is to have the mouse lay on its right or left side, with ventral side facing the X-ray source. We observed the lenticulostriate artery for the first time in living mice. Our result show that there are 4 to 5 lenticulostriate branches originating from the root of middle cerebral artery in each hemisphere. LSAs have an average diameter of 43±6.8 μm. There were no differences between LSAs from the left and right hemisphere (p<0.05). These results suggest that synchrotron radiation may provide a unique tool for experimental stroke research.

  11. Microangiography in Living Mice Using Synchrotron Radiation

    Science.gov (United States)

    Yuan, Falei; Wang, Yongting; Guan, Yongjing; Lu, Haiyan; Xie, Bohua; Tang, Yaohui; Xie, Honglan; Du, Guohao; Xiao, Tiqiao; Yang, Guo-Yuan

    2010-07-01

    Traditionally, there are no methods available to detect the fine morphologic changes of cerebrovasculature in small living animals such as rats and mice. Newly developed synchrotron radiation microangiography can achieve a fine resolution of several micrometers and had provided us with a powerful tool to study the cerebral vasculature in small animals. The purpose of this study is to identify the morphology of cerebrovasculature especially the structure of Lenticulostriate arteries (LSAs) in living mice using the synchrotron radiation source at Shanghai Synchrotron Radiation Facility (SSRF) in Shanghai, China. Adult CD-1 mice weighing 35-40 grams were anesthetized. Nonionic iodine (Omnipaque, 350 mg I /mL) was used as a contrast agent. The study was performed at the BL13W1 beam line at SSRF. The beam line was derived from a storage ring of electrons with an accelerated energy of 3.5 GeV and an average beam current of 200 mA. X-ray energy of 33.3 keV was used to produce the highest contrast image. Images were acquired every 172 ms by a x-ray camera (Photonic-Science VHR 1.38) with a resolution of 13 μm/pixel. The optimal dose of contrast agent is 100 μl per injection and the injecting rate is 33 μl/sec. The best position for imaging is to have the mouse lay on its right or left side, with ventral side facing the X-ray source. We observed the lenticulostriate artery for the first time in living mice. Our result show that there are 4 to 5 lenticulostriate branches originating from the root of middle cerebral artery in each hemisphere. LSAs have an average diameter of 43±6.8 μm. There were no differences between LSAs from the left and right hemisphere (p<0.05). These results suggest that synchrotron radiation may provide a unique tool for experimental stroke research.

  12. Glancing angle synchrotron X-ray diffraction

    International Nuclear Information System (INIS)

    Cernik, R.J.

    1996-01-01

    This paper describes in basic detail some of the techniques that can be used to study thin films and surfaces. These are all in the X-ray region and cover reflectivity, diffraction form polycrystalline films, textured films and single crystal films. Other effects such as fluorescence and diffuse scattering are mentioned but not discussed in detail. Two examples of the reflectivity from multilayers and the diffraction from iron oxide films are discussed. The advantages of the synchrotron for these studies is stressed and the experimental geometries that can be employed are described i detail. A brief bibliography is provided at the end to accompany this part of the 1996 Frascati school

  13. WE7000 network for KEK Proton Synchrotron

    International Nuclear Information System (INIS)

    Yamaguchi, Yuji; Yagyu, Hiroshi

    2000-01-01

    A new PC-Based measurement system, WE7000, has been developed. The WE7000 is based on a new concept and the leading-edge technologies, such as 250 Mbps high speed optical fiber network and complete Plug and Play mechanism. This paper describes an application to the betatron oscillation monitor and a magnetic field monitor of beam extraction system for neutrino experiment at 12 GeV Proton Synchrotron (PS) Accelerator in High Energy Accelerator Organization (KEK). It was found that these system are very effective in the operation of the accelerator. (author)

  14. Medical applications of synchrotron radiation in Australia

    International Nuclear Information System (INIS)

    Lewis, R.A.

    2005-01-01

    The Australian synchrotron is being built at Monash University near Melbourne. The 3 GeV machine is well-suited to the mid X-ray region and will have nine beamlines in its initial phase. The high level of biomedical research in Australia has led to the demand for a beamline capable of supporting medical research in both imaging and therapy. The design features for a versatile imaging and hard X-ray beamline capable of operating in the energy range 10-120 keV are outlined here together with a short review of some of the science that is envisaged

  15. High resolution synchrotron light analysis at ELSA

    Energy Technology Data Exchange (ETDEWEB)

    Switka, Michael; Zander, Sven; Hillert, Wolfgang [Bonn Univ. (Germany). Elektronen-Stretcher Anlage ELSA-Facility (ELSA)

    2013-07-01

    The pulse stretcher ring ELSA provides polarized electrons with energies up to 3.5 GeV for external hadron experiments. In order to suffice the need of stored beam intensities towards 200 mA, advanced beam instability studies need to be carried out. An external diagnostic beamline for synchrotron light analysis has been set up and provides the space for multiple diagnostic tools including a streak camera with time resolution of <1 ps. Beam profile measurements are expected to identify instabilities and reveal their thresholds. The effect of adequate countermeasures is subject to analysis. The current status of the beamline development is presented.

  16. Synchrotron radiation research facility conceptual design report

    International Nuclear Information System (INIS)

    1976-06-01

    A report is presented to define, in general outline, the extent and proportions, the type of construction, the schedule for accomplishment, and the estimated cost for a new Synchrotron Radiation Facility, as proposed to the Energy Research and Development Administration by the Brookhaven National Laboratory. The report is concerned only indirectly with the scientific and technological justification for undertaking this project; the latter is addressed explicitly in separate documents. The report does consider user requirements, however, in order to establish a basis for design development. Preliminary drawings, outline specifications, estimated cost data, and other descriptive material are included as supporting documentation on the current status of the project in this preconstruction phase

  17. Emittance growth from transient coherent synchrotron radiation

    International Nuclear Information System (INIS)

    Bohn, C.L.; Li, R.; Bisognano, J.J.

    1996-01-01

    If the energies of individual particles in a bunch change as the bunch traverses a bending system, even if it is achromatic, betatron oscillations can be excited. Consequently, the transverse emittance of the bunch will grow as it moves downstream. Short bunches may be particularly susceptible to emission of coherent synchrotron radiation which can act back on the particles to change their energies and trajectories. Because a bend spans a well-defined length and angle, the bunch-excited wakefield and its effect back on the bunch are inherently transient. We outline a recently developed theory of this effect and apply it to example bending systems

  18. Synchrotron radiation facilities in the USA

    International Nuclear Information System (INIS)

    Decker, G.

    1996-01-01

    With the successful commissioning and achievement of significant milestones at both the 7-GeV Advanced Photon Source (APS) and the 1.5- GeV Advanced Light Source (ALS) at Lawrence Berkeley National Laboratory, synchrotron radiation research capability in the United States holds the promise of many important discoveries in the decade to come. An overview of current accelerator commissioning performance at the American third-generation light sources, state-of-the-art developments at first- and second-generation sources, and a preview of fourth-generation source progress is presented

  19. Coherent Synchrotron Radiation effect in damping rings

    International Nuclear Information System (INIS)

    Raubenheimer, T

    2004-01-01

    Coherent Synchrotron Radiation (CSR) can play an important role by not only increasing the energy spread and emittance of a beam, but also leading to a potential instability. Previous studies of the CSR induced longitudinal instability were carried out for the CSR impedance due to dipole magnets. In this paper, the instability due to the CSR impedance from a wiggler is studied assuming a large wiggler parameter K. The primary consideration is a low frequency microwave-like instability in the damping rings of several linear collider projects. The threshold is determined by the instability with the longest possible wavelength

  20. CSNS magnet system and prototypes fabrication

    International Nuclear Information System (INIS)

    Deng Changdong; Chen Fusan; Sun Xianjing; Chen Wan; Sun Yaolin; Shi Caitu

    2008-01-01

    The 1.6 GeV synchrotron of China Spallation Neutron Source (CSNS) project is a Rapid Cycling Synchrotron (RCS), which accelerates a high-intensity proton beam from 80 MeV to 1.6 GeV at a repetition rate of 25 Hz. The RCS magnet system consists of 24 dipole magnets (main dipoles), 48 quadrupole magnets (main quadrupoles), 16 sextupole magnets, some tune shift quadrupoles and corrector magnets. All the magnets are of large aperture for a high beam power of 0.1 MW, one design issue is the fringe field at pole end. And the main dipoles and main quadrupoles work at 25 Hz repetition rate, the eddy current is an additional issue. In this paper the magnet design of the two kinds of main magnets will be described. (authors)

  1. Ferroelectrics under the Synchrotron Light: A Review

    Science.gov (United States)

    Fuentes-Cobas, Luis E.; Montero-Cabrera, María E.; Pardo, Lorena; Fuentes-Montero, Luis

    2015-01-01

    Currently, an intensive search for high-performance lead-free ferroelectric materials is taking place. ABO3 perovskites (A = Ba, Bi, Ca, K and Na; B = Fe, Nb, Ti, and Zr) appear as promising candidates. Understanding the structure–function relationship is mandatory, and, in this field, the roles of long- and short-range crystal orders and interactions are decisive. In this review, recent advances in the global and local characterization of ferroelectric materials by synchrotron light diffraction, scattering and absorption are analyzed. Single- and poly-crystal synchrotron diffraction studies allow high-resolution investigations regarding the long-range average position of ions and subtle global symmetry break-downs. Ferroelectric materials, under the action of electric fields, undergo crystal symmetry, crystallite/domain orientation distribution and strain condition transformations. Methodological aspects of monitoring these processes are discussed. Two-dimensional diffraction clarify larger scale ordering: polycrystal texture is measured from the intensities distribution along the Debye rings. Local order is investigated by diffuse scattering (DS) and X-ray absorption fine structure (XAFS) experiments. DS provides information about thermal, chemical and displacive low-dimensional disorders. XAFS investigation of ferroelectrics reveals local B-cation off-centering and oxidation state. This technique has the advantage of being element-selective. Representative reports of the mentioned studies are described. PMID:28787814

  2. Ferroelectrics under the Synchrotron Light: A Review

    Directory of Open Access Journals (Sweden)

    Luis E. Fuentes-Cobas

    2015-12-01

    Full Text Available Currently, an intensive search for high-performance lead-free ferroelectric materials is taking place. ABO3 perovskites (A = Ba, Bi, Ca, K and Na; B = Fe, Nb, Ti, and Zr appear as promising candidates. Understanding the structure–function relationship is mandatory, and, in this field, the roles of long- and short-range crystal orders and interactions are decisive. In this review, recent advances in the global and local characterization of ferroelectric materials by synchrotron light diffraction, scattering and absorption are analyzed. Single- and poly-crystal synchrotron diffraction studies allow high-resolution investigations regarding the long-range average position of ions and subtle global symmetry break-downs. Ferroelectric materials, under the action of electric fields, undergo crystal symmetry, crystallite/domain orientation distribution and strain condition transformations. Methodological aspects of monitoring these processes are discussed. Two-dimensional diffraction clarify larger scale ordering: polycrystal texture is measured from the intensities distribution along the Debye rings. Local order is investigated by diffuse scattering (DS and X-ray absorption fine structure (XAFS experiments. DS provides information about thermal, chemical and displacive low-dimensional disorders. XAFS investigation of ferroelectrics reveals local B-cation off-centering and oxidation state. This technique has the advantage of being element-selective. Representative reports of the mentioned studies are described.

  3. Synchrotrons for hadron therapy: Part I

    CERN Document Server

    Badano, L; Bryant, P; Crescenti, M; Holy, P; Knaus, P; Maier, A; Pullia, M; Rossi, S

    1999-01-01

    The treatment of cancer with accelerator beams has a long history with betatrons, linacs, cyclotrons and now synchrotrons being exploited for this purpose. Treatment techniques can be broadly divided into the use of spread-out beams and scanned 'pencil' beams. The Bragg-peak behaviour of hadrons makes them ideal candidates for the latter. The combination of precisely focused 'pencil' beams with controllable penetration (Bragg peak) and high, radio-biological efficiency (light ions) opens the way to treating the more awkward tumours that are radio-resistant, complex in shape and lodged against critical organs. To accelerate light ions (probably carbon) with pulse-to-pulse energy variation, a synchrotron is the natural choice. The beam scanning system is controlled via an on-line measurement of the particle flux entering the patient and, for this reason, the beam spill must be extended in time (seconds) by a slow-extraction scheme. The quality of the dose intensity profile ultimately depends on the uniformity o...

  4. Analytical fits to the synchrotron functions

    Science.gov (United States)

    Fouka, Mourad; Ouichaoui, Saad

    2013-06-01

    Accurate fitting formulae to the synchrotron function, F(x), and its complementary function, G(x), are performed and presented. The corresponding relative errors are less than 0.26% and 0.035% for F(x) and G(x), respectively. To this end we have, first, fitted the modified Bessel functions, K5/3(x) and K2/3(x). For all the fitted functions, the general fit expression is the same, and is based on the well known asymptotic forms for low and large values of x for each function. It consists of multiplying each asymptotic form by a function that tends to unity or zero for low and large values of x. Simple formulae are suggested in this paper, depending on adjustable parameters. The latter have been determined by adopting the Levenberg-Marquardt algorithm. The proposed formulae should be of great utility and simplicity for computing spectral powers and the degree of polarization for synchrotron radiation, both for laboratory and astrophysical applications.

  5. Long term ground movement of TRISTAN synchrotron

    International Nuclear Information System (INIS)

    Endo, K.; Ohsawa, Y.; Miyahara, M.

    1989-01-01

    The long term ground movement is estimated through the geological survey before a big accelerator is planned. For the case of TRISTAN-MR (main ring), its site was surveyed to reflect the underground information to the building prior to the construction. The movement of the synchrotron magnet mainly results from the structure of the tunnel. If an individual movement of the magnet exceeds a certain threshold limit, it gives a significant effect on the particle behavior in a synchrotron. Height of the quadrupole magnets were observed periodically during past two years at the TRISTAN-MR and their height differences along the 3 km circumference of the accelerator ring were decomposed into the Fourier components depicting the causes of the movements. Results shows the movement of the tunnel foundation which was also observed by the simultaneous measurement of both magnets and fiducial marks on the tunnel wall. The long term movement of the magnets is summarized with the geological survey prior to construction. 1 ref., 6 figs., 1 tab

  6. Impact system for ultrafast synchrotron experiments

    International Nuclear Information System (INIS)

    Jensen, B. J.; Owens, C. T.; Ramos, K. J.; Yeager, J. D.; Saavedra, R. A.; Luo, S. N.; Hooks, D. E.; Iverson, A. J.; Fezzaa, K.

    2013-01-01

    The impact system for ultrafast synchrotron experiments, or IMPULSE, is a 12.6-mm bore light-gas gun (<1 km/s projectile velocity) designed specifically for performing dynamic compression experiments using the advanced imaging and X-ray diffraction methods available at synchrotron sources. The gun system, capable of reaching projectile velocities up to 1 km/s, was designed to be portable for quick insertion/removal in the experimental hutch at Sector 32 ID-B of the Advanced Photon Source (Argonne, IL) while allowing the target chamber to rotate for sample alignment with the beam. A key challenge in using the gun system to acquire dynamic data on the nanosecond time scale was synchronization (or bracketing) of the impact event with the incident X-ray pulses (80 ps width). A description of the basic gun system used in previous work is provided along with details of an improved launch initiation system designed to significantly reduce the total system time from launch initiation to impact. Experiments were performed to directly measure the gun system time and to determine the gun performance curve for projectile velocities ranging from 0.3 to 0.9 km/s. All results show an average system time of 21.6 ± 4.5 ms, making it possible to better synchronize the gun system and detectors to the X-ray beam.

  7. Mapping prehistoric ghosts in the synchrotron

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, N.P.; Wogelius, R.A. [University of Manchester, School of Earth, Atmospheric, and Environmental Sciences, Manchester (United Kingdom); University of Manchester, Williamson Research Centre for Molecular Environmental Science, Manchester (United Kingdom); Bergmann, U. [SLAC National Accelerator Laboratory, Linac Coherent Light Source, Menlo Park, CA (United States); Larson, P. [Black Hills Institute of Geological Research, Inc., Hill City, SD (United States); Sellers, W.I. [University of Manchester, Faculty of Life Sciences, Manchester (United Kingdom); Manning, P.L. [University of Manchester, School of Earth, Atmospheric, and Environmental Sciences, Manchester (United Kingdom); University of Manchester, Williamson Research Centre for Molecular Environmental Science, Manchester (United Kingdom); University of Pennsylvania, Department of Earth and Environmental Science, Philadelphia, PA (United States)

    2013-04-15

    The detailed chemical analysis of fossils has the potential to reveal great insight to the composition, preservation and biochemistry of ancient life. Such analyses would ideally identify, quantify, and spatially resolve the chemical composition of preserved bone and soft tissue structures, but also the embedding matrix. Mapping the chemistry of a fossil in situ can place constraints on mass transfer between the enclosing matrix and the preserved organism(s), and therefore aid in distinguishing taphonomic processes from original chemical zonation remnant within the fossils themselves. Conventional analytical methods, such as scanning electron microscopy (SEM) and pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) have serious limitations in this case, primarily, an inability to provide large (i.e., decimeter) scale chemical maps. Additionally, vacuum chamber size and the need for destructive sampling preclude analysis of large and precious fossil specimens. However, the recent development of Synchrotron Rapid Scanning X-ray Fluorescence (SRS-XRF) at the Stanford Synchrotron Radiation Lightsource (SSRL) allows the non-destructive chemical analysis and imaging of major, minor, and trace element concentrations of large paleontological and archeological specimens in rapid scanning times. Here we present elemental maps of a fossil reptile produced using the new SRS-XRF method. Our results unequivocally show that preserved biological structures are not simply impressions or carbonized remains, but possess a remnant of the original organismal biochemistry. We show that SRS-XRF is a powerful new tool for the study of paleontological and archaeological samples. (orig.)

  8. Synchrotron radiation from a Helical Wiggler

    International Nuclear Information System (INIS)

    Irani, A.A.

    1979-01-01

    The use of Wiggler magnets as an improved source of synchrotron radiation from high energy electron storage rings was proposed a few years ago. Since then it has also been suggested that synchrotron radiation from Wiggler magnets placed in proton machines can be used to monitor energy, dimensions and position of the beam and that this effect is even more interesting in proton storage rings where the need to see the beam is greater. Most of the calculations carried out so far consider radiation from a single particle in a Wiggler which is appropriate when the beam is radiating incoherently. In this paper a general formalism is developed for the case when the beam radiates coherently. These results are then applied to both electron and proton storage rings. For the electron case, an expression is derived for the length of the bunch to be used as a more intense coherent radiation source. For proton machines the radiation can be used to measure energy, current, transverse dimensions and longitudinal density variations in the beam

  9. Synchrotron radiation from a helical wiggler

    International Nuclear Information System (INIS)

    Irani, A.A.

    1979-01-01

    The use of wiggler magnets as an improved source of synchrotron radiation from high energy electron storage rings was proposed a few years age. Since then it has also been suggested that synchrotron radiation from wiggler magnets placed in proton machines can be used to monitor energy, dimensions and position of the beam and that this effect is even more interesting in proton storage rings where the need to see the beam is greater. Most of the calculations carried out so far consider radiation from a single particle in a wiggler which is appropriate when the beam is radiating incoherently. A general formalism is presented for the case when the beam radiates coherently. These results are applied to both electron and proton storage rings. For the electron case, an expression is derived for the length of the bunch to use it as a more intense coherent radiation source. For proton machines the radiation can be used to measure energy, current, transverse dimensions and longitudinal density variations in the beam

  10. Compact synchrotron radiation depth lithography facility

    Science.gov (United States)

    Knüppel, O.; Kadereit, D.; Neff, B.; Hormes, J.

    1992-01-01

    X-ray depth lithography allows the fabrication of plastic microstructures with heights of up to 1 mm but with the smallest possible lateral dimensions of about 1 μm. A resist is irradiated with ``white'' synchrotron radiation through a mask that is partially covered with x-ray absorbing microstructures. The plastic microstructure is then obtained by a subsequent chemical development of the irradiated resist. In order to irradiate a reasonably large resist area, the mask and the resist have to be ``scanned'' across the vertically thin beam of the synchrotron radiation. A flexible, nonexpensive and compact scanner apparatus has been built for x-ray depth lithography at the beamline BN1 at ELSA (the 3.5 GeV Electron Stretcher and Accelerator at the Physikalisches Institut of Bonn University). Measurements with an electronic water level showed that the apparatus limits the scanner-induced structure precision to not more than 0.02 μm. The whole apparatus is installed in a vacuum chamber thus allowing lithography under different process gases and pressures.

  11. Application of circular polarized synchrotron radiation

    International Nuclear Information System (INIS)

    Miyahara, Tsuneaki; Kawata, Hiroshi

    1988-03-01

    The idea of using the polarizing property of light for physical experiment by controlling it variously has been known from old time, and the Faraday effect and the research by polarizing microscopy are its examples. The light emitted from the electron orbit of an accelerator has the different polarizing characteristics from those of the light of a laboratory light source, and as far as observing it within the electron orbit plane, it becomes linearly polarized light. By utilizing this property well, research is carried out at present in synchrotron experimental facilities. Recently, the technology related to the insert type light cources using permanent magnets has advanced remarkably, and circular polarized light has become to be producible. If the light like this can be obtained with the energy not only in far ultraviolet region but also to x-ray region at high luminance, new possibility should open. At the stage that the design of an insert type light source was finished, and its manufacture was started, the research on the method of evaluating the degree of circular polarization and the research on the utilization of circular polarized synchrotron radiation are earnestly carried out. In this report, the results of researches presented at the study meeting are summarized. Moreover, the design and manufacture of the beam lines for exclusive use will be carried out. (Kako, I.)

  12. Berkeley Lab's ALS generates femtosecond synchrotron radiation

    CERN Document Server

    Robinson, A L

    2000-01-01

    A team at Berkeley's Advanced Light Source has shown how a laser time-slicing technique provides a path to experiments with ultrafast time resolution. A Lawrence Berkeley National Laboratory team has succeeded in generating 300 fs pulses of synchrotron radiation at the ALS synchrotron radiation machine. The team's members come from the Materials Sciences Division (MSD), the Center for Beam Physics in the Accelerator and Fusion Research Division and the Advanced Light Source (ALS). Although this proof-of principle experiment made use of visible light on a borrowed beamline, the laser "time-slicing" technique at the heart of the demonstration will soon be applied in a new bend magnet beamline that was designed specially for the production of femtosecond pulses of X-rays to study long-range and local order in condensed matter with ultrafast time resolution. An undulator beamline based on the same technique has been proposed that will dramatically increase the flux and brightness. The use of X-rays to study the c...

  13. Calibration of AXAF Mirrors Using Synchrotron Radiation

    Science.gov (United States)

    Graessle, D. E.; Fitch, J.; Harris, B.; Hsieh, P.; Nguyen, D.; Hughes, J.; Schwartz, D.; Blake, R.

    1995-12-01

    Over the past five years, the SAO AXAF Mission Support Team has been developing methods and systems to provide a tunable, narrow-energy-bandwidth calibration of the reflecting efficiency of the AXAF High Resolution Mirror Assembly. A group of synchrotron beamlines at the National Synchrotron Light Source was selected for this calibration. Measurements and analysis are now available for the 2-12 keV energy range. An X-ray beam with energy purity E/Delta E ~ 5000 has been used to calibrate several witness flats which were coated simultaneously with elements of the flight mirror. In the iridium-edge range, (2010-3200 eV), these may be the first measurements ever to be reported. Optical constants for the iridium have been derived from a fit of reflectance versus grazing angle to a Fresnel equation model for the 2-12 keV energy range. The eight AXAF HRMA elements are being coated individually; however reflectance results are quite consistent from coating run to coating run for the first few pieces. The measurement precision is approximately 0.2%-0.4%. Residuals of the fit are nearly always within 1.0% of the data values, in the angle ranges of interest to AXAF.

  14. Molecular environmental science and synchrotron radiation sources

    Energy Technology Data Exchange (ETDEWEB)

    Brown, G.E. Jr. [Stanford Univ., CA (United States)

    1995-12-31

    Molecular environmental science is a relatively new field but focuses on the chemical and physical forms of toxic and/or radioactive contaminants in soils, sediments, man-made waste forms, natural waters, and the atmosphere; their possible reactions with inorganic and organic compounds, plants, and organisms in the environment; and the molecular-level factors that control their toxicity, bioavailability, and transport. The chemical speciation of a contaminant is a major factor in determining its behavior in the environment, and synchrotron-based X-ray absorption fine structure (XAFS) spectroscopy is one of the spectroscopies of choice to quantitatively determine speciation of heavy metal contaminants in situ without selective extraction or other sample treatment. The use of high-flux insertion device beam lines at synchrotron sources and multi-element array detectors has permitted XAFS studies of metals such as Se and As in natural soils at concentration levels as low as 50 ppm. The X-ray absorption near edge structure of these metals is particularly useful in determining their oxidation state. Examples of such studies will be presented, and new insertion device beam lines under development at SSRL and the Advanced Photon Source for molecular environmental science applications will be discussed.

  15. Performances of BNL high-intensity synchrotrons

    International Nuclear Information System (INIS)

    Weng, W.T.

    1998-03-01

    The AGS proton synchrotron was completed in 1960 with initial intensity in the 10 to the 10th power proton per pulse (ppp) range. Over the years, through many upgrades and improvements, the AGS now reached an intensity record of 6.3 x 10 13 ppp, the highest world intensity record for a proton synchrotron on a single pulse basis. At the same time, the Booster reached 2.2 x 10 13 ppp surpassing the design goal of 1.5 x 10 13 ppp due to the introduction of second harmonic cavity during injection. The intensity limitation caused by space charge tune spread and its relationship to injection energy at 50 MeV, 200 MeV, and 1,500 MeV will be presented as well as many critical accelerator manipulations. BNL currently participates in the design of an accumulator ring for the SNS project at Oak Ridge. The status on the issues of halo formation, beam losses and collimation are also presented

  16. Synchrotron radiation in art and archaeology SRA 2005

    International Nuclear Information System (INIS)

    Pollard, A.M.; Janssens, K.; Artioli, G.; Young, M.L.; Casadio, F.; Schnepp, S.; Marvin, J.; Dunand, D.C.; Almer, J.; Fezzaa, K.; Lee, W.K.; Haeffner, D.R.; Reguer, S.; Dillmann, Ph.; Mirambet, F.; Susini, J.; Lagarde, P.; Pradell, T.; Molera, J.; Brunetti, B.; D'acapito, F.; Maurizio, C.; Mazzoldi, P.; Padovani, S.; Sgamellotti, A.; Garges, F.; Etcheverry, M.P.; Flank, A.M.; Lagarde, P.; Marcus, M.A.; Scheidegger, A.M.; Grolimund, D.; Pallot-Frossard, I.; Smith, A.D.; Jones, M.; Gliozzo, E.; Memmi-Turbanti, I.; Molera, J.; Vendrell, M.; Mcconachie, G.; Skinner, T.; Kirkman, I.W.; Pantos, E.; Wallert, A.; Kanngiesser, B.; Hahn, O.; Wilke, M.; NekaT, B.; Malzer, W.; Erko, A.; Chalmin, E.; Vignaud, C.; Farges, F.; Susini, J.; Menu, M.; Sandstrom, M.; Cotte, M.; Kennedy, C.J.; Wess, T.J.; Muller, M.; Murphy, B.; Roberts, M.A.; Burghammer, M.; Riekel, C.; Gunneweg, J.; Pantos, E.; Dik, J.; Tafforeau, P.; Boistel, R.; Boller, E.; Bravin, A.; Brunet, M.; Chaimanee, Y.; Cloetens, P.; Feist, M.; Hoszowska, J.; Jaeger, J.J.; Kay, R.F.; Lazzari, V.; Marivaux, L.; Nel, A.; Nemoz, C.; Thibault, X.; Vignaud, P.; Zabler, S.; Sciau, P.; Goudeau, P.; Tamura, N.; Doormee, E.; Kockelmann, W.; Adriaens, A.; Ryck, I. de; Leyssens, K.; Hochleitner, B.; Schreiner, M.; Drakopoulos, M.; Snigireva, I.; Snigirev, A.; Sanchez Del Rio, M.; Martinetto, P.; Dooryhee, E.; Suarez, M.; Sodo, A.; Reyes-Valerio, C.; Haro Poniatowski, E.; Picquart, M.; Lima, E.; Reguera, E.; Gunneweg, J.; Reiche, I.; Berger, A.; Bevers, H.; Duval, A.

    2005-01-01

    Materials - bones, artifacts, artwork,.... - lie at the heart of both archaeology and art conservation. Synchrotron radiation techniques provide powerful ways to interrogate these records of our physical and cultural past. In this workshop we will discuss and explore the current and potential applications of synchrotron radiation science to problems in archaeology and art conservation. This document gathers the abstracts of the presentations

  17. National synchrotron light source basic design and project status

    International Nuclear Information System (INIS)

    van Steenbergen, A.

    1981-01-01

    A summary description and the basic design parameters of the National Synchrotron Light Source, a facility for the generation of intense synchrotron radiation in the vuv and x-ray range is presented, the parameters of the sources are given, the presently planned facility beam lines are tabulated and the status of the project is indicated

  18. Third generation synchrotron radiation applied to materials science

    International Nuclear Information System (INIS)

    Kaufmann, E.N.; Yun, W.

    1993-01-01

    Utility of synchrotron radiation for characterization of materials and ramifications of availability of new third-generation, high-energy, high-intensity sources of synchrotron radiation are discussed. Examples are given of power of x-ray analysis techniques to be expected with these new machines

  19. Synchrotron radiation facilities at DESY, a status report

    International Nuclear Information System (INIS)

    Koch, E.E.

    1979-12-01

    A short summary of the developments which have led to the present extensive use of Synchrotron Radiation at DESY is presented and a description of the Synchrotron Radiation facilities presently available and under development is given with emphasis on the new HASYLAB project at the storage ring DORIS. (orig.) 891 HSI/orig. 892 MKO

  20. First turn simulations in the cooler synchrotron COSY

    International Nuclear Information System (INIS)

    Dinev, D.

    1991-07-01

    This paper is devoted to the first turn correction and related problems in particle accelerators of synchrotron type. The paper consists of two parts. The first part is a survey of the existing methods for first turn steering. The second part is entirely devoted to the first turn in the cooler synchrotron COSY which is under assembling in KFA-Julich, Germany. (orig.)

  1. A synchrotron radiation facility for x-ray astronomy

    DEFF Research Database (Denmark)

    Hall, C.J.; Lewis, R.A.; Christensen, Finn Erland

    1997-01-01

    A proposal for an x-ray optics test facility based at a synchrotron radiation source is presented. The facility would incorporate a clean preparation area, and a large evacuable test area. The advantages of using a synchrotron as the source of the test radiation are discussed. These include the a...

  2. Status of the National Synchrotron Light Source project

    International Nuclear Information System (INIS)

    Heese, R.N.

    1981-01-01

    The National Synchrotron Light Source is in its final stages of construction, and as the turn-on time for the 700 MeV vuv storage ring draws near, an overview of the project is presented. Emphasis is placed on the linac and booster synchrotron performance and the status of major subsystems

  3. Low frequency interference between short synchrotron radiation sources

    Directory of Open Access Journals (Sweden)

    F. Méot

    2001-06-01

    Full Text Available A recently developed analytical formalism describing low frequency far-field synchrotron radiation (SR is applied to the calculation of spectral angular radiation densities from interfering short sources (edge, short magnet. This is illustrated by analytical calculation of synchrotron radiation from various assemblies of short dipoles, including an “isolated” highest density infrared SR source.

  4. Synchrotron radiation X-ray microfluorescence techniques

    Indian Academy of Sciences (India)

    Synchrotron X-ray imaging systems with fluorescence techniques was developed for biomedical researches in Brazilian Synchrotron Laboratory. An X-ray fluorescence microtomography system was implemented to analyse human prostate and breast samples and an X-ray microfluorescence system was implemented to ...

  5. Synchrotron radiation in art and archaeology SRA 2005

    Energy Technology Data Exchange (ETDEWEB)

    Pollard, A M; Janssens, K; Artioli, G; Young, M L; Casadio, F; Schnepp, S; Marvin, J; Dunand, D C; Almer, J; Fezzaa, K; Lee, W K; Haeffner, D R; Reguer, S; Dillmann, Ph; Mirambet, F; Susini, J; Lagarde, P; Pradell, T; Molera, J; Brunetti, B; D' acapito, F; Maurizio, C; Mazzoldi, P; Padovani, S; Sgamellotti, A; Garges, F; Etcheverry, M P; Flank, A M; Lagarde, P; Marcus, M A; Scheidegger, A M; Grolimund, D; Pallot-Frossard, I; Smith, A D; Jones, M; Gliozzo, E; Memmi-Turbanti, I; Molera, J; Vendrell, M; Mcconachie, G; Skinner, T; Kirkman, I W; Pantos, E; Wallert, A; Kanngiesser, B; Hahn, O; Wilke, M; NekaT, B; Malzer, W; Erko, A; Chalmin, E; Vignaud, C; Farges, F; Susini, J; Menu, M; Sandstrom, M; Cotte, M; Kennedy, C J; Wess, T J; Muller, M; Murphy, B; Roberts, M A; Burghammer, M; Riekel, C; Gunneweg, J; Pantos, E; Dik, J; Tafforeau, P; Boistel, R; Boller, E; Bravin, A; Brunet, M; Chaimanee, Y; Cloetens, P; Feist, M; Hoszowska, J; Jaeger, J J; Kay, R F; Lazzari, V; Marivaux, L; Nel, A; Nemoz, C; Thibault, X; Vignaud, P; Zabler, S; Sciau, P; Goudeau, P; Tamura, N; Doormee, E; Kockelmann, W; Adriaens, A; Ryck, I de; Leyssens, K; Hochleitner, B; Schreiner, M; Drakopoulos, M; Snigireva, I; Snigirev, A; Sanchez Del Rio, M; Martinetto, P; Dooryhee, E; Suarez, M; Sodo, A; Reyes-Valerio, C; Haro Poniatowski, E; Picquart, M; Lima, E; Reguera, E; Gunneweg, J; Reiche, I; Berger, A; Bevers, H; Duval, A

    2005-07-01

    Materials - bones, artifacts, artwork,.... - lie at the heart of both archaeology and art conservation. Synchrotron radiation techniques provide powerful ways to interrogate these records of our physical and cultural past. In this workshop we will discuss and explore the current and potential applications of synchrotron radiation science to problems in archaeology and art conservation. This document gathers the abstracts of the presentations.

  6. Dynamic J-R Characteristics of RCS Pipe Materials for Ulchin Unit 3/4. (Evaluation of Dynamic Strain Aging Effects)

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jun Hwa; Lee, Bong Sang; Yoon, Ji Hyun; Oh, Jong Myung; Kim, Jin Won [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1997-09-01

    5 materials (45 1T-CT specimens) were tested to evaluate dynamic J-R characteristics of RCS Pipe Materials for Ulchin Unit 3/4 (Evaluation of Dynamic Strain Aging Effects). The tests were performed by DCPD method at 316 deg C and 25 deg C. The loading rates were 1000mm/min and 2000mm/min. The objectives of this project were to obtain the dynamic J-R curves data of ferritic steels for application of LBB to the RCS pipes of Ulchin Unit 3/4. The test results showed that all of the tested dynamic J-R curves of 5 materials were above the lower bound curve of static J-R curve of pipe materials for Ulchin Unit 3/4. 10 refs., 4 tabs., 16 figs. (author)

  7. Engineering description of the OMS/RCS/DAP modes used in the HP-9825A High Fidelity Relative Motion Program (HFRMP)

    Science.gov (United States)

    Wilson, S. W.

    1978-01-01

    Simplified mathematical models are reported for the space shuttle's Orbital Maneuvering System (OMS), Reaction Control System (RCS), and on-orbit Digital Autopilot (DAP) that have been incorporated in the High-Fidelity Relative Motion Program (HFRMP) for the HP-9825A desk-top calculator. Comparisons were made between data generated by the HFRMP and by the Space Shuttle Functional Simulator (SSFS), which models the cited shuttle systems in much greater detail. These data include propellant requirements for representative translational maneuvers, rotational maneuvers, and attitude maintenance options. Also included are data relating to on-orbit trajectory deviations induced by RCS translational cross coupling. Potential close-range stationkeeping problems that are suggested by HFRMP simulations of 80 millisecond (as opposed to 40 millisecond) DAP cycle effects are described. The principal function of the HFRMP is to serve as a flight design tool in the area of proximity operations.

  8. A Perspective on Reagent Diversity and Non-covalent Binding of Reactive Carbonyl Species (RCS and Effector Reagents in Non-enzymatic Glycation (NEG: Mechanistic Considerations and Implications for Future Research

    Directory of Open Access Journals (Sweden)

    Kenneth J. Rodnick

    2017-06-01

    Full Text Available This perspective focuses on illustrating the underappreciated connections between reactive carbonyl species (RCS, initial binding in the nonenzymatic glycation (NEG process, and nonenzymatic covalent protein modification (here termed NECPM. While glucose is the central species involved in NEG, recent studies indicate that the initially-bound glucose species in the NEG of human hemoglobin (HbA and human serum albumin (HSA are non-RCS ring-closed isomers. The ring-opened glucose, an RCS structure that reacts in the NEG process, is most likely generated from previously-bound ring-closed isomers undergoing concerted acid/base reactions while bound to protein. The generation of the glucose RCS can involve concomitantly-bound physiological species (e.g., inorganic phosphate, water, etc.; here termed effector reagents. Extant NEG schemes do not account for these recent findings. In addition, effector reagent reactions with glucose in the serum and erythrocyte cytosol can generate RCS (e.g., glyoxal, glyceraldehyde, etc.. Recent research has shown that these RCS covalently modify proteins in vivo via NECPM mechanisms. A general scheme that reflects both the reagent and mechanistic diversity that can lead to NEG and NECPM is presented here. A perspective that accounts for the relationships between RCS, NEG, and NECPM can facilitate the understanding of site selectivity, may help explain overall glycation rates, and may have implications for the clinical assessment/control of diabetes mellitus. In view of this perspective, concentrations of ribose, fructose, Pi, bicarbonate, counter ions, and the resulting RCS generated within intracellular and extracellular compartments may be of importance and of clinical relevance. Future research is also proposed.

  9. Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy.

    Science.gov (United States)

    Tschernutter, M; Schlichtenbrede, F C; Howe, S; Balaggan, K S; Munro, P M; Bainbridge, J W B; Thrasher, A J; Smith, A J; Ali, R R

    2005-04-01

    The Royal College of Surgeons (RCS) rat is a well-characterized model of autosomal recessive retinitis pigmentosa (RP) due to a defect in the retinal pigment epithelium (RPE). It is homozygous for a null mutation in the gene encoding , a receptor tyrosine kinase found in RPE cells, that is required for phagocytosis of shed photoreceptor outer segments. The absence of Mertk results in accumulation of outer segment debris. This subsequently leads to progressive loss of photoreceptor cells. In order to evaluate the efficacy of lentiviral-mediated gene replacement therapy in the RCS rat, we produced recombinant VSV-G pseudotyped HIV-1-based lentiviruses containing a murine Mertk cDNA driven by a spleen focus forming virus (SFFV) promoter. The vector was subretinally injected into the right eye of 10-day-old RCS rats; the left eye was left untreated as an internal control. Here, we present a detailed assessment of the duration and extent of the morphological rescue and the resulting functional benefits. We examined animals at various time points over a period of 7 months by light and electron microscopy, and electroretinography. We observed correction of the phagocytic defect, slowing of photoreceptor cell loss and preservation of retinal function for up to 7 months. This study demonstrates the potential of gene therapy approaches for the treatment of retinal degenerations caused by defects specific to the RPE and supports the use of lentiviral vectors for the treatment of such disorders.

  10. Excitation of nuclear states by synchrotron radiation

    International Nuclear Information System (INIS)

    Olariu, Albert

    2003-01-01

    We study the excitation of nuclear states by gamma ray beams of energy up to 200 keV produced as synchrotron radiation. We consider the possibility to populate an excited state |i> in two steps, from the ground state |g> to an intermediary state |n> which decays by gamma emission or internal conversion to a lower state |i>. The aim of this study is to establish that the probability P 2 of the two-step transition |g> → |n> → |i> should be greater than the probability P 1 of the direct transition |g> → |i>. The probabilities P 1 and P 2 correspond to a radiation pulse of duration equal to the half-time of the state |i>. We have written a computer program in C++ which computes the probability P 2 , the ratio P 2 /P 1 and the rate C 2 of the two-step transitions for any nuclei and different configurations of states. The program uses a database which contains information on the energy levels, half-lives, spins and parities of nuclear states and on the relative intensities of the nuclear transitions. If the half-lives or the relative intensities are not known the program uses the Weisskopf estimates for the transition half-lives. An interpolation program of internal conversion coefficients has also been used. We listed the values obtained for P 2 , P 2 /P 1 and C 2 in a number of cases in which P 2 is significant from the 2900 considered cases. The states |i> and |n> have the energies E i and E n , the corresponding half-lives being t i and t n . The spectral density of the synchrotron radiation has been considered to be 10 12 photons cm -2 s -1 eV -1 . We listed only the cases for which the relative intensities of the transitions from levels |n> and |i> to lower states are known. The calculations carried out in this study allowed us to identify nuclei for which P 2 has relatively great values. In the listed cases P 2 /P 1 >>1, so that the two-step excitation by synchrotron radiation is more efficient than the direct excitation |g> → |i>. For a sample having 10

  11. Remote Cloud Sensing Intensive Observation Period (RCS-IOP) millimeter-wave radar calibration and data intercomparison

    Energy Technology Data Exchange (ETDEWEB)

    Sekelsky, S.M.; Firda, J.M.; McIntosh, R.E. [Univ. of Massachusetts, Amherst, MA (United States)] [and others

    1996-04-01

    During April 1994, the University of Massachusetts (UMass) and the Pennsylvania State University (Penn State) fielded two millimeter-wave atmospheric radars in the Atmospheric Radiation Measurement Remote Cloud Sensing Intensive Operation Period (RCS-IOP) experiment. The UMass Cloud Profiling Radar System (CPRS) operates simultaneously at 33.12 GHz and 94.92 GHz through a single antenna. The Penn State radar operates at 93.95 GHz and has separate transmitting and receiving antennas. The two systems were separated by approximately 75 meters and simultaneously observed a variety of cloud types at verticle incidence over the course of the experiment. This abstract presents some initial results from our calibration efforts. An absolute calibration of the UMass radar was made from radar measurements of a trihedral corner reflector, which has a known radar cross-section. A relative calibration of between the Penn State and UMass radars is made from the statistical comparison of zenith pointing measurements of low altitude liquid clouds. Attenuation is removed with the aid of radiosonde data, and the difference in the calibration between the UMass and Penn State radars is determined by comparing the ratio of 94-GHz and 95-GHz reflectivity values to a model that accounts for parallax effects of the two antennas used in the Penn State system.

  12. Preservation of visual cortical function following retinal pigment epithelium transplantation in the RCS rat using optical imaging techniques.

    Science.gov (United States)

    Gias, Carlos; Jones, Myles; Keegan, David; Adamson, Peter; Greenwood, John; Lund, Ray; Martindale, John; Johnston, David; Berwick, Jason; Mayhew, John; Coffey, Peter

    2007-04-01

    The aim of this study was to determine the extent of cortical functional preservation following retinal pigment epithelium (RPE) transplantation in the Royal College of Surgeons (RCS) rat using single-wavelength optical imaging and spectroscopy. The cortical responses to visual stimulation in transplanted rats at 6 months post-transplantation were compared with those from age-matched untreated dystrophic and non-dystrophic rats. Our results show that cortical responses were evoked in non-dystrophic rats to both luminance changes and pattern stimulation, whereas no response was found in untreated dystrophic animals to any of the visual stimuli tested. In contrast, a cortical response was elicited in most of the transplanted rats to luminance changes and in many of those a response was also evoked to pattern stimulation. Although the transplanted rats did not respond to high spatial frequency information we found evidence of preservation in the cortical processing of luminance changes and low spatial frequency stimulation. Anatomical sections of transplanted rat retinas confirmed the capacity of RPE transplantation to rescue photoreceptors. Good correlation was found between photoreceptor survival and the extent of cortical function preservation determined with optical imaging techniques. This study determined the efficacy of RPE transplantation to preserve visual cortical processing and established optical imaging as a powerful technique for its assessment.

  13. A model for calculation of RCS pressure during reflux boiling under reduced inventory conditions and its assessment against PKL data

    International Nuclear Information System (INIS)

    Palmrose, D.E.; Mandl, R.

    1991-01-01

    Based on the occurrence of a number of plant incidents during low power and shutdown operating conditions, the Nuclear Regulatory Commission (NRC) has initiated several programs to better quantify risk during these periods. One specific issue of interest is the loss of residual heat removal (RHR) under reduced coolant inventory conditions. This issue is also of interest in the Federal Republic of Germany and an experiment was performed in the integral PKL-3 experimental facility at Siemens-KWU to supply applicable data. Recently, an effort has been undertaken at the Idaho National Engineering Laboratory (INEL) to identify and analyze the important thermal-hydraulic phenomena in pressurized water reactors following loss of vital AC power and consequent loss of the RHR system during reduced inventory operation. The thermal-hydraulic response of a nuclear steam supply system (NSSS) with a closed reactor coolant system (RCS) to loss of residual heat removal cooling capability is investigated in this report. The specific processes investigated include: boiling of the coolant in the core and reflux condensation in the steam generators, the corresponding pressure increase in the reactor coolant system, the heat transfer mechanisms on the primary and secondary sides of the steam generators, the effects of air or other noncondensible gas on the heat transfer processes, and void fraction distributions on the primary side of the system. Mathematical models of these physical processes were developed and validated against experimental data from the PKL 3B 4.5 Experiment

  14. The Synchrotron Topography Project (STP) at the National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Bilello, J.C.; Hmelo, A.B.; Liu, J.M.; Herley, P.J.; Chen, H.; Birnbaum, H.K.; Illinois Univ., Urbana; Green, R.E. Jr.

    1983-01-01

    The collaborators have participated in the Synchrotron Topography Project (STP) which has designed and developed instrumentation for an X-ray topography station at the National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory (BNL). The two principle instruments constructed consist of a White Beam Camera (WBC) and a Multiple Crystal Camera (MCC) with high planar collimation and wide area image coverage. It is possible to perform in situ studies in a versatile environmental chamber equipped with a miniature mechanical testing stage for both the WBC and MCC systems. Real-time video imaging plus a rapid feed cassette holder for high resolution photographic plates is available for recording topographs. Provisions are made for other types of photon detection as well as spectroscopy. The facilities for the entire station have been designed for remote operation using a LSI-11/23 plus suitable interfacing. These instruments will be described briefly and the current status of the program will be reviewed. (orig.)

  15. Plane grating monochromators for synchrotron radiation

    International Nuclear Information System (INIS)

    Howells, M.R.

    1979-01-01

    The general background and theoretical basis of plane grating monochromators (PGM's) is reviewed and the particular case of grazing incidence PGM's suitable for use with synchrotron radiation is considered in detail. The theory of reflection filtering is described and the problem of the finite source distance is shown to be of special importance with high brightness storage rings. The design philosophy of previous instruments is discussed and a new scheme proposed, aimed at dealing with the problem of the finite source distance. This scheme, involving a parabolic collimating mirror fabricated by diamond turning, is considered in the context of Wolter-type telescopes and microscopes. Some practical details concerning an instrument presently under construction using the new design are presented

  16. 3D Detectors for Synchrotron Applications

    CERN Document Server

    Pennicard, D

    2009-01-01

    3D detectors are a novel variety of photodiode radiation detector, invented by Parker, Kenney and Segal (1997). Instead of having n- and p-type contacts on the front and back surfaces of a silicon substrate, like a standard photodiode, they have columns of doped material passing through the thickness of the silicon. This structure means that the detector can combine a reasonable substrate thickness with a very small electrode spacing, resulting in a low depletion voltage, fast charge collection and low charge sharing. These detectors have a couple of promising applications. Their fast charge collection and low depletion voltage should make them very radiation-tolerant. So, they could be used for future particle physics experiments at the Super Large Hadron Collider (SLHC), where high levels of radiation damage are expected. Also, their low charge sharing means they could potentially improve X-ray diffraction measurements at synchrotrons such as Diamond Light Source. This would allow these experiments, for exa...

  17. Synchrotron radiation facilities for chemical applications

    International Nuclear Information System (INIS)

    Hatano, Yoshihiko

    1995-01-01

    Synchrotron radiation (SR) research is of great importance in understanding radiation chemistry, physics, and biology. It is also clearly recognized in the international chemical community that chemical applications of SR are greatly advanced and divided into 1) Molecular Spectroscopy and Dynamics Studies-Gases, Surfaces, and Condensed Matter- , 2) Radiation Chemistry and Photochemistry, 3) X-ray Structural and XAFS Studies-Crystals, Surfaces, and Liquids- , 4) Analytical Chemistry, and 5) Synthesis or R and D of New Materials. In this paper, a survey is given of recent advances in the application of SR to the chemistry of excitation and ionization of molecules, i.e., SR chemistry, in the wavelength region between near-ultraviolet and hard X-rays. The topics will be chosen from those obtained at some leading SR facilities. (J.P.N.)

  18. Coherent synchrotron radiation experiments for the LCLS

    International Nuclear Information System (INIS)

    Carlsten, B.E.; Russell, S.J.

    1998-01-01

    The authors describe a coherent synchrotron radiation experiment planned at Los Alamos to support the design of the Linac Coherent Light Source (LCLS) x-ray FEL. Preliminary simulations of the LCLS compressors show that a clever tuning strategy can be used to minimize the electron's beam emittance growth due to noninertial space-charge forces by employing a delicate cancellation of these forces. The purpose of the Los Alamos experiment, using a sub-picosecond chicane compressor, is to benchmark these simulations tools. In this paper, the authors present detailed numerical simulations of the experiment, and point out unique signatures of this effect that are measurable. As predicted previously, the largest emittance growths and induced energy spreads result from the nonradiative components of this space-charge force

  19. Electron beam spectrum monitor using synchrotron light

    International Nuclear Information System (INIS)

    Reagan, D.; Hostetler, T.E.

    1979-03-01

    This instrument shows the positions, widths, and shapes of momentum spectra of SLAC beams. It uses synchrotron light produced when the beam is deflected by a magnet. Some of the light is focused on the face of an image splitter consisting of acrylic light pipes. The light pipes illuminate twelve photomultiplier tubes. Pulses from the PM tubes are integrated, multiplexed, and displayed on an oscilloscope. The resolution of the instrument is usually better than 0.2%. It has some advantages over the secondary emitter foil spectrum monitors (SEM's) currently in use at SLAC. It need never be put out of service to avoid disturbing the beam. It is as sensitive as the most sensitive SLAC SEM. (Its performance has been optimized for high-current beams; it can easily be made much more sensitive.) It provides information on a pulse-to-pulse basis and, with better cables, could indicate electron beam pulse shapes

  20. Optical substrate materials for synchrotron radiation beamlines

    International Nuclear Information System (INIS)

    Howells, M.R.; Paquin, R.A.

    1997-06-01

    The authors consider the materials choices available for making optical substrates for synchrotron radiation beam lines. They find that currently the optical surfaces can only be polished to the required finish in fused silica and other glasses, silicon, CVD silicon carbide, electroless nickel and 17-4 PH stainless steel. Substrates must therefore be made of one of these materials or of a metal that can be coated with electroless nickel. In the context of material choices for mirrors they explore the issues of dimensional stability, polishing, bending, cooling, and manufacturing strategy. They conclude that metals are best from an engineering and cost standpoint while the ceramics are best from a polishing standpoint. They then give discussions of specific materials as follows: silicon carbide, silicon, electroless nickel, Glidcop trademark, aluminum, precipitation-hardening stainless steel, mild steel, invar and superinvar. Finally they summarize conclusions and propose ideas for further research

  1. Microfabrication of crosslinked PTFE by synchrotron radiation

    International Nuclear Information System (INIS)

    Sato, Yasunori; Yamaguchi, Daichi; Oshima, Akihiro; Washio, Masakazu; Katoh, Takanori; Aoki, Yasushi; Ikeda, Shigetoshi; Tanaka, Shigeru

    2003-01-01

    Microfabrication of crosslinked polytetrafluoroethylene (PTFE) using synchrotron radiation (SR) has been demonstrated for production of micro-components applicable to radiation fields. The method of microfabrication was readily capable of obtaining a microstructure with aspect-ratio of 25 made of crosslinked PTFE. The etching rate of crosslinked PTFE was higher than that of non-crosslinked PTFE. The results show that the etching rate of crosslinked PTFE depends only on the degree of crosslinking. The effect of molecular motion on etching process was discussed from temperature dependence on etching rate. Moreover, in order to examine whether any change of chemical structures and crystallinity would be induced by SR-irradiation on PTFE, SR-irradiated PTFE was measured by NMR spectroscopy and DSC analysis. The results showed that the crosslinking reaction of PTFE would be induced by SR-irradiation in the solid state. (author)

  2. Channels in cell membranes and synchrotron radiation

    International Nuclear Information System (INIS)

    Yan Xiaohui; Tian Liang; Zhang Xinyi

    2004-01-01

    For long time a lot of scientists have devoted to study how matter, such as water molecules and K + , Na + , Ca 2+ , Cl - ions, move through cell membranes and complete the matter exchange between the inside and outside of cells. Peter Agre discovered and characterized the first water channel protein in 1988 and Roderick MacKinnon elucidated the structural and mechanistic basis for ion channel function in 1998. These achievements have made it possible for us to 'see' these exquisitely designed molecular machines in action at the atomic level. The Nobel Prize in Chemistry for 2003 is shared between these two scientists. In determining the high resolution 3D structure of these channels, the synchrotron X-ray diffraction plays an important role

  3. Synchrotron radiation total reflection for rainwater analysis

    International Nuclear Information System (INIS)

    Simabuco, Silvana M.; Matsumoto, Edson

    1999-01-01

    Total reflection X-ray fluorescence analysis excited with synchrotron radiation (SR-TXRF) has been used for rainwater trace element analysis. The samples were collected in four different sites at Campinas City, SP. Standard solutions with gallium as internal standard were prepared for the calibration system. Rainwater samples of 10 μl were putted onto Perspex reflector disk, dried on vacuum and analyzed for 100 s measuring time. The detection limits obtained for K-shell varied from 29 ng.ml -1 for sulfur to 1.3 ng.ml -1 for zinc and copper, while for L-shell the values were 4.5 ng.ml -1 for mercury and 7.0 ng.ml -1 for lead. (author)

  4. A guide to synchrotron radiation science

    CERN Document Server

    Sato, Shigeru; Munro, Ian; Lodha, G S

    2015-01-01

    Synchrotron Radiation (SR), as a light source is now in use around the world to provide brilliant radiation from the infrared into the soft and hard X-ray regions. It is an indispensible and essential tool to establish the physic-chemical characteristics of materials and surfaces from an atomic and molecular view point. It is being applied to topics which range from mineralogy to protein crystallography, embracing research in areas from the physical to the life sciences. This new guide is a concise yet comprehensive and easily readable introduction to an expanding area of science. It presents in a readily assimilable form the basic concepts of SR science from its generation principles, through source design and operation to the principles of instruments for SR exploitation followed by a survey of its actual applications in selected research fields, including spectroscopy, diffractometry, microanalysis and chemical processing.

  5. Helical magnetized wiggler for synchrotron radiation laser

    International Nuclear Information System (INIS)

    Wang Mei; Park, S.Y.; Hirshfield, J.L.

    1999-01-01

    A helical magnetized iron wiggler has been built for a novel infrared synchrotron radiation laser (SRL) experiment. The wiggler consists of four periods of helical iron structure immersed in a solenoid field. This wiggler is to impart transverse velocity to a prebunched 6 MeV electron beam, and thus to obtain a desired high orbit pitch ratio for the SRL. Field tapering at beam entrance is considered and tested on a similar wiggler. Analytic and simulated characteristics of wigglers of this type are discussed and the performance of the fabricated wigglers is demonstrated experimentally. A 4.7 kG peak field was measured for a 6.4 mm air gap and a 5.4 cm wiggler period at a 20 kG solenoid field. The measured helical fields compare favorably with the analytical solution. This type of helical iron wigglers has the potential to be scaled to small periods with strong field amplitude

  6. Synchrotron radiation in solid state chemistry

    International Nuclear Information System (INIS)

    Ghigna, Paolo; Pin, Sonia; Spinolo, Giorgio; Newton, Mark A.; Chiara Tarantino, Serena; Zema, Michele

    2011-01-01

    An approach towards the reactivity in the solid state is proposed, primarily based on recognizing the crucial role played by the interfacial free energy and by the topotactical relationship between the two reactants, which in turn control formation of the new phase and its spatial and orientational relationships with respect to the parent phases. Using one of the reactants in the form of film, the ratio between bulk and interfacial free energy can be changed, and the effect of interfacial free energy is maximized. The role of Synchrotron Radiation in such an approach is exemplified by using a new developed technique for μ-XANES mapping with nanometric resolution for studying the reactivity of thin films of NiO onto differently oriented Al 2 O 3 single crystals. The result obtained allowed us to speculate about the rate determining step of the NiO+Al 2 O 3 →NiAl 2 O 4 interfacial reaction.

  7. Mirrors for synchrotron-radiation beamlines

    International Nuclear Information System (INIS)

    Howells, M.R.

    1993-09-01

    The authors consider the role of mirrors in synchrotron-radiation beamlines and discuss the optical considerations involved in their design. They discuss toroidal, spherical, elliptical, and paraboloidal mirrors in detail with particular attention to their aberration properties. They give a treatment of the sine condition and describe its role in correcting the coma of axisymmetric systems. They show in detail how coma is inevitable in single-reflection, grazing-incidence systems but correctable in two-reflection systems such as those of the Wolter type. In an appendix, they give the theory of point aberrations of reflectors of a general shape and discuss the question of correct naming of aberrations. In particular, a strict definition of coma is required if attempts at correction are to be based on the sine condition

  8. CVD diamond windows for infrared synchrotron applications

    International Nuclear Information System (INIS)

    Sussmann, R.S.; Pickles, C.S.J.; Brandon, J.R.; Wort, C.J.H.; Coe, S.E.; Wasenczuk, A.; Dodge, C.N.; Beale, A.C.; Krehan, A.J.; Dore, P.; Nucara, A.; Calvani, P.

    1998-01-01

    This paper describes the attributes that make diamond a unique material for infrared synchrotron beam experiments. New developments in diamond synthesised by Chemical Vapour Deposition (CVD) promise to extend the range of applications which have been hitherto limited by the availability and cost of large-size single-crystal diamond. Polycrystalline CVD diamond components such as large (100 mm) diameter windows with extremely good transparency over a wide spectral range are now commercially available. Properties of CVD diamond of relevance to optical applications, such as mechanical strength, thermal conductivity and absolute bulk absorption, are discussed. It is shown that although some of the properties of CVD diamond (similar to other polycrystalline industrial ceramics) are affected by the grain structure, currently produced CVD diamond optical components have the quality and performance required for numerous demanding applications

  9. A synchrotron radiation study of strontium titanate

    International Nuclear Information System (INIS)

    Maslen, E.N.; Spadaccini, N.; Ito, T.; Marumo, F.; Satow, Y.

    1995-01-01

    Electron deformation densities Δρ for SrTiO 3 have been determined from diffraction data measured using focused synchrotron radiation with λ = 0.7000 (2) A at the Photon Factory, KEK, Japan. Corrections for secondary extinction were estimated from the variation of diffraction intensity with path length, and checked from the λ-dependence of the strong intensities indicated by measurements using a weaker parallel beam with λ = 0.5000 (2) A. The 0.7 A study is more precise than earlier analyses with Mo Kα radiation. The difference density near the Ti nucleus is mildly anisotropic, and the Δρ topography is similar to those for closed-shell atoms in related perovskite structures. (orig.)

  10. Helical magnetized wiggler for synchrotron radiation laser

    CERN Document Server

    Wang Mei; Hirshfield, J L

    1999-01-01

    A helical magnetized iron wiggler has been built for a novel infrared synchrotron radiation laser (SRL) experiment. The wiggler consists of four periods of helical iron structure immersed in a solenoid field. This wiggler is to impart transverse velocity to a prebunched 6 MeV electron beam, and thus to obtain a desired high orbit pitch ratio for the SRL. Field tapering at beam entrance is considered and tested on a similar wiggler. Analytic and simulated characteristics of wigglers of this type are discussed and the performance of the fabricated wigglers is demonstrated experimentally. A 4.7 kG peak field was measured for a 6.4 mm air gap and a 5.4 cm wiggler period at a 20 kG solenoid field. The measured helical fields compare favorably with the analytical solution. This type of helical iron wigglers has the potential to be scaled to small periods with strong field amplitude.

  11. Application of synchrotron radiation in archaeology

    Energy Technology Data Exchange (ETDEWEB)

    Nakai, Izumi [Science University of Tokyo, Faculty of Science, Department of Applied Chemistry, Tokyo (Japan)

    2002-07-01

    This paper reports current status of archaeological application of synchrotron radiation (SR). The advantages of SR in archaeological research and various application possibilities of X-ray powder diffraction (XPD), X-ray fluorescence (XRF) and X-ray absorption fine structure (XAFS) analyses of objects and materials of cultural heritage value are demonstrated through a number of case studies from literatures. They include XPD characterizations of Egyptian cosmetic powder, Attic Black Gloss, and pigments in Gothic altarpieces, provenance analysis of Old-Kutani china wares by high energy XRF, and XAFS analyses to reveal to origin of red color in Satsuma copper-ruby glass and role of iron in Maya blue. (author)

  12. Illuminating magma shearing processes via synchrotron imaging

    Science.gov (United States)

    Lavallée, Yan; Cai, Biao; Coats, Rebecca; Kendrick, Jackie E.; von Aulock, Felix W.; Wallace, Paul A.; Le Gall, Nolwenn; Godinho, Jose; Dobson, Katherine; Atwood, Robert; Holness, Marian; Lee, Peter D.

    2017-04-01

    Our understanding of geomaterial behaviour and processes has long fallen short due to inaccessibility into material as "something" happens. In volcanology, research strategies have increasingly sought to illuminate the subsurface of materials at all scales, from the use of muon tomography to image the inside of volcanoes to the use of seismic tomography to image magmatic bodies in the crust, and most recently, we have added synchrotron-based x-ray tomography to image the inside of material as we test it under controlled conditions. Here, we will explore some of the novel findings made on the evolution of magma during shearing. These will include observations and discussions of magma flow and failure as well as petrological reaction kinetics.

  13. Gravitational perturbation theory and synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Breuer, R A [Max-Planck-Institut fuer Physik und Astrophysik, Muenchen (F.R. Germany). Inst. fuer Astrophysik

    1975-01-01

    This article presents methods and results for a gravitational perturbation theory which treats massless fields as linearized perturbations of an arbitrary gravitational vacuum background spacetime. The formalism is outlined for perturbations of type (22) spacetimes. As an application, high-frequency radiation emitted by particles moving approximately on relativistic circular geodesic orbits is computed. More precisely, the test particle assumption is made; throughout it is therefore assumed that the reaction of the radiation on the particle motion is negligible. In particular, these orbits are studied in the gravitational field of a spherically symmetric (Schwarzschild-) black hole as well as of a rotating (Kerr-) black hole. In this model, the outgoing radiation is highly focussed and of much higher fequency than the orbital frequency, i.e. one is dealing with 'gravitational synchrotron radiation'.

  14. Tune measurement in the NSLS booster synchrotron

    International Nuclear Information System (INIS)

    Blum, E.B.; Nawrocky, R.

    1993-01-01

    The NSLS booster synchrotron can accelerate an electron beam from approximately 80 to 750 MeV in 0.7 sec. The betatron tunes can change during acceleration by as much as 0.1 units, causing beam loss as they cross resonance lines. Precise measurements with a conventional swept spectrum analyzer have always been difficult because of the rapid variation of tune as the magnets are ramped. We are now using a system based on a Tektronix 3052 digital spectrum analyzer that can obtain a complete frequency spectrum over a 10 MHz bandwidth in 200 μsec. Betatron oscillations are stimulated for the measurements by applying white noise to the beam through stripline electrodes. We will describe the instrumentation, our measurements of tune as a function time during the acceleration cycle, and the resulting improvements to the booster operation

  15. Silicon Pixel Detectors for Synchrotron Applications

    CERN Document Server

    Stewart, Graeme Douglas

    Recent advances in particle accelerators have increased the demands being placed on detectors. Novel detector designs are being implemented in many different areas including, for example, high luminosity experiments at the LHC or at next generation synchrotrons. The purpose of this thesis was to characterise some of these novel detectors. The first of the new detector types is called a 3D detector. This design was first proposed by Parker, Kenney and Segal (1997). In this design, doped electrodes are created that extend through the silicon substrate. When compared to a traditional photodiode with electrodes on the opposing surfaces, the 3D design can combine a reasonable detector thickness with a small electrode spacing resulting in fast charge collection and limited charge sharing. The small electrode spacing leads to the detectors having lower depletion voltages. This, combined with the fast collection time, makes 3D detectors a candidate for radiation hard applications. These applications include the upgra...

  16. European synchrotron radiation facility at Risoe

    International Nuclear Information System (INIS)

    1981-07-01

    The results of the feasibility study on a potential European Synchrotron Radiation Facility site at Risoe, Denmark, can be summarized as follows: The site is located in a geologically stable area. The ground is fairly flat, free from vibrations and earth movements, and the foundation properties are considered generally good. The study is based upon the machine concept and main geometry as presented in the ESF feasibility study of May 1979. However, the proposed site could accomodate a larger machine (e.g. 900 m of circumference) or a multi-facility centre. The site is located in the vicinity of Risoe National Laboratory, a R and D establishment with 850 employees and a well-developed technical and scientific infrastructure, which can provide support to the ESRF during the plant construction and operation. In particular the possible combination of synchrotron radiation with the existing neutron scattering facilities in DR 3 is emphasized. The site is located 35 km west of Copenhagen with easy access to the scientific, technological and industrial organizations in the metropolitan area. The regional infrastructure ensures easy and fast communication between the ESRF and locations in the host country as well as abroad. The site is located 35 minutes drive from Copenhagen International Airport and on a main communication route out of Copenhagen. The estimated time duration for the design, construction and commissioning of ESRF phase 1 - taking into account national regulatory procedures - is consistent with that of the ESF feasibility study, i.e. approx. 6 years. The estimated captal costs associated with site-specific structures are consistent with those of the ESF feasibility study, taking into account price increase between 1979 and 1981. It should be emphasized that the study is based upon technical and scientific assessments only, and does not reflect any official position or approval from appropriate authorities. (author)

  17. Brightness of synchrotron radiation from wigglers

    International Nuclear Information System (INIS)

    Geloni, Gianluca; Kocharyan, Vitali; Saldin, Evgeni

    2014-12-01

    According to literature, while calculating the brightness of synchrotron radiation from wigglers, one needs to account for the so called 'depth-of-field' effects. In fact, the particle beam cross section varies along the wiggler. It is usually stated that the effective photon source size increases accordingly, while the brightness is reduced. Here we claim that this is a misconception originating from an analysis of the wiggler source based on geometrical arguments, regarded as almost self-evident. According to electrodynamics, depth-of-field effects do not exist: we demonstrate this statement both theoretically and numerically, using a well-known first-principle computer code. This fact shows that under the usually accepted approximations, the description of the wiggler brightness turns out to be inconsistent even qualitatively. Therefore, there is a need for a well-defined procedure for computing the brightness from a wiggler source. We accomplish this task based on the use of a Wigner function formalism. In the geometrical optics limit computations can be performed analytically. Within this limit, we restrict ourselves to the case of the beam size-dominated regime, which is typical for synchrotron radiation facilities in the X-ray wavelength range. We give a direct demonstration of the fact that the apparent horizontal source size is broadened in proportion to the beamline opening angle and to the length of the wiggler. While this effect is well-understood, a direct proof appears not to have been given elsewhere. We consider the problem of the calculation of the wiggler source size by means of numerical simulations alone, which play the same role of an experiment. We report a significant numerical disagreement between exact calculations and approximations currently used in literature.

  18. Liquid metal cooling of synchrotron optics

    International Nuclear Information System (INIS)

    Smither, R.K.

    1993-01-01

    The installation of insertion devices at existing synchrotron facilities around the world has stimulated the development of new ways to cool the optical elements in the associated x-ray beamlines. Argonne has been a leader in the development of liquid metal cooling for high heat load x-ray optics for the next generation of synchrotron facilities. The high thermal conductivity, high volume specific heat, low kinematic viscosity, and large working temperature range make liquid metals a very efficient heat transfer fluid. A wide range of liquid metals were considered in the initial phase of this work. The most promising liquid metal cooling fluid identified to date is liquid gallium, which appears to have all the desired properties and the fewest number of undesired features of the liquid metals examined. Besides the special features of liquid metals that make them good heat transfer fluids, the very low vapor pressure over a large working temperature range make liquid gallium an ideal cooling fluid for use in a high vacuum environment. A leak of the liquid gallium into the high vacuum and even into very high vacuum areas will not result in any detectable vapor pressure and may even improve the vacuum environment as the liquid gallium combines with any water vapor or oxygen present in the system. The practical use of a liquid metal for cooling silicon crystals and other high heat load applications depends on having a convenient and efficient delivery system. The requirements for a typical cooling system for a silicon crystal used in a monochromator are pumping speeds of 2 to 5 gpm (120 cc per sec to 600 cc per sec) at pressures up to 100 psi. No liquid metal pump with these capabilities was available commercially when this project was started, so it was necessary to develop a suitable pump in house

  19. Constitutively reduced sensory capacity promotes better recovery after spinal cord-injury (SCI) in blind rats of the dystrophic RCS strain.

    Science.gov (United States)

    Rink, Svenja; Bendella, Habib; Alsolivany, Kurdin; Meyer, Carolin; Woehler, Aliona; Jansen, Ramona; Isik, Zeynep; Stein, Gregor; Wennmachers, Sina; Nakamura, Makoto; Angelov, Doychin N

    2018-01-01

    We compared functional, electrophysiological and morphological parameters after SCI in two groups of rats Sprague Dawley (SD) rats with normal vision and blind rats from a SD-substrain "Royal College of Surgeons" (SD/RCS) who lose their photoreceptor cells after birth due to a genetic defect in the retinal pigment epithelium. For these animals skin-, intramuscular-, and tendon receptors are major available means to resolve spatial information. The purpose of this study was to check whether increased sensitivity in SD/RCS rats would promote an improved recovery after SCI. All rats were subjected to severe compression of the spinal cord at vertebra Th8, spinal cord segment Th10. Recovery of locomotion was analyzed at 1, 3, 6, 9, and 12 weeks after SCI using video recordings of beam walking and inclined ladder climbing. Five functional parameters were studied: foot-stepping angle (FSA), rump-height index (RHI) estimating paw placement and body weight support, respectively, number of correct ladder steps (CLS) assessing skilled hindlimb movements, the BBB-locomotor score and an established urinary bladder score (BS). Sensitivity tests were followed by electrophysiological measurement of M- and H-wave amplitudes from contractions of the plantar musculature after stimulation of the tibial nerve. The closing morphological measurements included lesion volume and expression of astro- and microglia below the lesion. Numerical assessments of BBB, FSA, BS, lesion volume and GFAP-expression revealed no significant differences between both strains. However, compared to SD-rats, the blind SD/RCS animals significantly improved RHI and CLS by 6 - 12 weeks after SCI. To our surprise the withdrawal latencies in the blind SD/RCS rats were longer and the amplitudes of M- and H-waves lower. The expression of IBA1-immunoreactivity in the lumbar enlargement was lower than in the SD-animals. The longer withdrawal latencies suggest a decreased sensitivity in the blind SD/RCS rats, which

  20. Dynamic response of a typical synchrotron magnet/girder assembly

    International Nuclear Information System (INIS)

    Jendrzejczyk, J.A.; Smith, R.K.; Vogt, M.E.

    1993-06-01

    In the Advanced Photon Source, the synchrotron booster ring accelerates positrons to the required energy level of 7 GeV. The positrons are then injected into the storage ring where they continue to orbit for 10--15 h. The storage ring quadrupoles have very stringent vibration criteria that must be satisfied to ensure that beam emittance growth is within acceptable limits, viz., <10%. Because the synchrotron booster ring is not operated after particle insertion into the storage ring, its vibration response is not a critical issue relative to the performance of the storage ring beam. Nevertheless, the synchrotron pulses at a frequency of 2 Hz, and if a vibration response frequency of the synchrotron magnet/girder assembly were to coincide with the pulsation frequency or its near harmonics, large-amplitude motion could result, with the effect that it could compromise the operation of the synchrotron. Due to the complex dynamics of the synchrotron magnet/girder assembly, it is necessary to measure the dynamic response of a prototypic assembly and its components to ensure that the inherent dynamic response frequencies are not equal to 2 Hz or any near harmonics. Dynamic-response measurement of the synchrotron girder assembly and component magnets is the subject of this report