WorldWideScience

Sample records for rapid prototyping capability

  1. Rapid prototyping for biomedical engineering: current capabilities and challenges.

    Science.gov (United States)

    Lantada, Andrés Díaz; Morgado, Pilar Lafont

    2012-01-01

    A new set of manufacturing technologies has emerged in the past decades to address market requirements in a customized way and to provide support for research tasks that require prototypes. These new techniques and technologies are usually referred to as rapid prototyping and manufacturing technologies, and they allow prototypes to be produced in a wide range of materials with remarkable precision in a couple of hours. Although they have been rapidly incorporated into product development methodologies, they are still under development, and their applications in bioengineering are continuously evolving. Rapid prototyping and manufacturing technologies can be of assistance in every stage of the development process of novel biodevices, to address various problems that can arise in the devices' interactions with biological systems and the fact that the design decisions must be tested carefully. This review focuses on the main fields of application for rapid prototyping in biomedical engineering and health sciences, as well as on the most remarkable challenges and research trends.

  2. Rapid Prototyping Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The ARDEC Rapid Prototyping (RP) Laboratory was established in December 1992 to provide low cost RP capabilities to the ARDEC engineering community. The Stratasys,...

  3. Review on CNC-Rapid Prototyping

    International Nuclear Information System (INIS)

    M Nafis O Z; Nafrizuan M Y; Munira M A; Kartina J

    2012-01-01

    This article reviewed developments of Computerized Numerical Control (CNC) technology in rapid prototyping process. Rapid prototyping (RP) can be classified into three major groups; subtractive, additive and virtual. CNC rapid prototyping is grouped under the subtractive category which involves material removal from the workpiece that is larger than the final part. Richard Wysk established the use of CNC machines for rapid prototyping using sets of 2½-D tool paths from various orientations about a rotary axis to machine parts without refixturing. Since then, there are few developments on this process mainly aimed to optimized the operation and increase the process capabilities to stand equal with common additive type of RP. These developments include the integration between machining and deposition process (hybrid RP), adoption of RP to the conventional machine and optimization of the CNC rapid prototyping process based on controlled parameters. The article ended by concluding that the CNC rapid prototyping research area has a vast space for improvement as in the conventional machining processes. Further developments and findings will enhance the usage of this method and minimize the limitation of current approach in building a prototype.

  4. Patient specific ankle-foot orthoses using rapid prototyping.

    Science.gov (United States)

    Mavroidis, Constantinos; Ranky, Richard G; Sivak, Mark L; Patritti, Benjamin L; DiPisa, Joseph; Caddle, Alyssa; Gilhooly, Kara; Govoni, Lauren; Sivak, Seth; Lancia, Michael; Drillio, Robert; Bonato, Paolo

    2011-01-12

    Prefabricated orthotic devices are currently designed to fit a range of patients and therefore they do not provide individualized comfort and function. Custom-fit orthoses are superior to prefabricated orthotic devices from both of the above-mentioned standpoints. However, creating a custom-fit orthosis is a laborious and time-intensive manual process performed by skilled orthotists. Besides, adjustments made to both prefabricated and custom-fit orthoses are carried out in a qualitative manner. So both comfort and function can potentially suffer considerably. A computerized technique for fabricating patient-specific orthotic devices has the potential to provide excellent comfort and allow for changes in the standard design to meet the specific needs of each patient. In this paper, 3D laser scanning is combined with rapid prototyping to create patient-specific orthoses. A novel process was engineered to utilize patient-specific surface data of the patient anatomy as a digital input, manipulate the surface data to an optimal form using Computer Aided Design (CAD) software, and then download the digital output from the CAD software to a rapid prototyping machine for fabrication. Two AFOs were rapidly prototyped to demonstrate the proposed process. Gait analysis data of a subject wearing the AFOs indicated that the rapid prototyped AFOs performed comparably to the prefabricated polypropylene design. The rapidly prototyped orthoses fabricated in this study provided good fit of the subject's anatomy compared to a prefabricated AFO while delivering comparable function (i.e. mechanical effect on the biomechanics of gait). The rapid fabrication capability is of interest because it has potential for decreasing fabrication time and cost especially when a replacement of the orthosis is required.

  5. Patient specific ankle-foot orthoses using rapid prototyping

    Directory of Open Access Journals (Sweden)

    Sivak Seth

    2011-01-01

    Full Text Available Abstract Background Prefabricated orthotic devices are currently designed to fit a range of patients and therefore they do not provide individualized comfort and function. Custom-fit orthoses are superior to prefabricated orthotic devices from both of the above-mentioned standpoints. However, creating a custom-fit orthosis is a laborious and time-intensive manual process performed by skilled orthotists. Besides, adjustments made to both prefabricated and custom-fit orthoses are carried out in a qualitative manner. So both comfort and function can potentially suffer considerably. A computerized technique for fabricating patient-specific orthotic devices has the potential to provide excellent comfort and allow for changes in the standard design to meet the specific needs of each patient. Methods In this paper, 3D laser scanning is combined with rapid prototyping to create patient-specific orthoses. A novel process was engineered to utilize patient-specific surface data of the patient anatomy as a digital input, manipulate the surface data to an optimal form using Computer Aided Design (CAD software, and then download the digital output from the CAD software to a rapid prototyping machine for fabrication. Results Two AFOs were rapidly prototyped to demonstrate the proposed process. Gait analysis data of a subject wearing the AFOs indicated that the rapid prototyped AFOs performed comparably to the prefabricated polypropylene design. Conclusions The rapidly prototyped orthoses fabricated in this study provided good fit of the subject's anatomy compared to a prefabricated AFO while delivering comparable function (i.e. mechanical effect on the biomechanics of gait. The rapid fabrication capability is of interest because it has potential for decreasing fabrication time and cost especially when a replacement of the orthosis is required.

  6. Automated Loading and Unloading of the Stratasys FDM 1600 Rapid Prototyping System

    OpenAIRE

    Brockmeier, Oivind

    2000-01-01

    Rapid prototyping systems have advanced significantly with respect to material capabilities, fabrication speed, and surface quality. However, build jobs are still manually activated one at a time. The result is non-productive machine time whenever an operator is not at hand to make a job changeover. A low-cost auxiliary system, named Continuous Layered Manufacturing (CLM), has been developed to automatically load and unload the FDM 1600 rapid prototyping system (Stratasys, Inc.). The modifica...

  7. Rapid prototyping: een veelbelovende methode

    NARCIS (Netherlands)

    Haverman, T.M.; Karagozoglu, K.H.; Prins, H.; Schulten, E.A.J.M.; Forouzanfar, T.

    2013-01-01

    Rapid prototyping is a method which makes it possible to produce a three-dimensional model based on two-dimensional imaging. Various rapid prototyping methods are available for modelling, such as stereolithography, selective laser sintering, direct laser metal sintering, two-photon polymerization,

  8. [Rapid prototyping: a very promising method].

    Science.gov (United States)

    Haverman, T M; Karagozoglu, K H; Prins, H-J; Schulten, E A J M; Forouzanfar, T

    2013-03-01

    Rapid prototyping is a method which makes it possible to produce a three-dimensional model based on two-dimensional imaging. Various rapid prototyping methods are available for modelling, such as stereolithography, selective laser sintering, direct laser metal sintering, two-photon polymerization, laminated object manufacturing, three-dimensional printing, three-dimensional plotting, polyjet inkjet technology,fused deposition modelling, vacuum casting and milling. The various methods currently being used in the biomedical sector differ in production, materials and properties of the three-dimensional model which is produced. Rapid prototyping is mainly usedforpreoperative planning, simulation, education, and research into and development of bioengineering possibilities.

  9. Rapid Prototyping: An Alternative Instructional Design Strategy.

    Science.gov (United States)

    Tripp, Steven D.; Bichelmeyer, Barbara

    1990-01-01

    Discusses the nature of instructional design and describes rapid prototyping as a feasible model for instructional system design (ISD). The use of prototyping in software engineering is described, similarities between software design and instructional design are discussed, and an example is given which uses rapid prototyping in designing a…

  10. Rapid Prototyping and the Human Factors Engineering Process

    Science.gov (United States)

    2016-08-29

    conventional systems development techniques. It is not clear, however, exactly how rapid prototyping could be used in relation to conventional human...factors engineering analyses. Therefore, an investigation of the use of the V APS virtual prototyping system was carried out in five organizations. The...results show that a variety of task analysis approaches can be used to initiate rapid prototyping . Overall, it appears that rapid prototyping

  11. Using the adaptive blockset for simulation and rapid prototyping

    DEFF Research Database (Denmark)

    Ravn, Ole

    1999-01-01

    the gap between simulation and prototype controller implementation. This is done using the code generation capabilities of Real Time Workshop in combination with C s-function blocks for adaptive control in Simulink. In the paper the design of each group of blocks normally fund in adaptive controllers...... is outlined. The block types are, identification, controller design, controller and state variable filter.The use of the Adaptive Blockset is demonstrated using a simple laboratory setup. Both the use of the blockset for simulation and for rapid prototyping of a real-time controller are shown.......The paper presents the design considerations and implementational aspects of the Adaptive Blockset for Simulink which has been developed in a prototype implementation. The basics of indirect adaptive controllers are summarized. The concept behind the Adaptive Blockset for Simulink is to bridge...

  12. Designing Instructor-Led Schools with Rapid Prototyping.

    Science.gov (United States)

    Lange, Steven R.; And Others

    1996-01-01

    Rapid prototyping involves abandoning many of the linear steps of traditional prototyping; it is instead a series of design iterations representing each major stage. This article describes the development of an instructor-led course for midlevel auditors using the principles and procedures of rapid prototyping, focusing on the savings in time and…

  13. Rapid Prototyping in Instructional Design: Creating Competencies

    Science.gov (United States)

    Fulton, Carolyn D.

    2010-01-01

    Instructional designers working in rapid prototyping environments currently do not have a list of competencies that help to identify the knowledge, skills, and attitudes (KSAs) required in these workplaces. This qualitative case study used multiple cases in an attempt to identify rapid prototyping competencies required in a rapid prototyping…

  14. Application of rapid prototyping technology in the prototype manufacturing for evaluation of NPP components and equipments

    International Nuclear Information System (INIS)

    Park, C. Y.; Kim, J. W.; Shon, H. K.; Choi, H. S.; Yang, D. Y.

    2001-01-01

    A brief overview of rapid prototyping technology in which a part with complex shape can be produced easily and rapidly in a layer-by-layer additive manner is given in this article. In addition, a prototype model of a complex fan is manufactured using three-dimensional solid CAD modeling and Laminated Object Manufacturing (LOM), a rapid prototyping technology. This enables designers to verify and modify design rapidly at an early stage of product development; and the prototype model of a fan can be used as a pattern for various secondary casting process such as vacumm casting, lost-paper casting to make prototypes of a fan. It has been shown that the combination of three-dimensional solid CAD modeling and rapid prototyping technology can reduce greatly the cost and time of prototyping of fans and turbine blades in comparison with conventional CNC machining. It should also be noted that rapid prototyping technology enables the visualization of various physical and chemical defects at a nuclear power plant so that it can help engineers understand those defects in an effective way

  15. Rapid prototyping using robot welding : process description

    OpenAIRE

    Ribeiro, António Fernando; Norrish, John

    1997-01-01

    Rapid Prototyping is a relatively recent technique to produce component prototypes for industry in a much shorter period of time, since the time to market a product is essential to its success. A new Rapid Prototyping process which uses metal as the raw material had been under development at Cranfield University in the last few years. The process uses a Gas Metal Arc fusion welding robot which deposits successive layers of metal in such way that it forms a 3D solid component. Firstly, a CAD s...

  16. [A new method of fabricating photoelastic model by rapid prototyping].

    Science.gov (United States)

    Fan, Li; Huang, Qing-feng; Zhang, Fu-qiang; Xia, Yin-pei

    2011-10-01

    To explore a novel method of fabricating the photoelastic model using rapid prototyping technique. A mandible model was made by rapid prototyping with computerized three-dimensional reconstruction, then the photoelastic model with teeth was fabricated by traditional impression duplicating and mould casting. The photoelastic model of mandible with teeth, which was fabricated indirectly by rapid prototyping, was very similar to the prototype in geometry and physical parameters. The model was of high optical sensibility and met the experimental requirements. Photoelastic model of mandible with teeth indirectly fabricated by rapid prototyping meets the photoelastic experimental requirements well.

  17. Rapid prototyping of soil moisture estimates using the NASA Land Information System

    Science.gov (United States)

    Anantharaj, V.; Mostovoy, G.; Li, B.; Peters-Lidard, C.; Houser, P.; Moorhead, R.; Kumar, S.

    2007-12-01

    The Land Information System (LIS), developed at the NASA Goddard Space Flight Center, is a functional Land Data Assimilation System (LDAS) that incorporates a suite of land models in an interoperable computational framework. LIS has been integrated into a computational Rapid Prototyping Capabilities (RPC) infrastructure. LIS consists of a core, a number of community land models, data servers, and visualization systems - integrated in a high-performance computing environment. The land surface models (LSM) in LIS incorporate surface and atmospheric parameters of temperature, snow/water, vegetation, albedo, soil conditions, topography, and radiation. Many of these parameters are available from in-situ observations, numerical model analysis, and from NASA, NOAA, and other remote sensing satellite platforms at various spatial and temporal resolutions. The computational resources, available to LIS via the RPC infrastructure, support e- Science experiments involving the global modeling of land-atmosphere studies at 1km spatial resolutions as well as regional studies at finer resolutions. The Noah Land Surface Model, available with-in the LIS is being used to rapidly prototype soil moisture estimates in order to evaluate the viability of other science applications for decision making purposes. For example, LIS has been used to further extend the utility of the USDA Soil Climate Analysis Network of in-situ soil moisture observations. In addition, LIS also supports data assimilation capabilities that are used to assimilate remotely sensed soil moisture retrievals from the AMSR-E instrument onboard the Aqua satellite. The rapid prototyping of soil moisture estimates using LIS and their applications will be illustrated during the presentation.

  18. ADVANCEMENT OF RAPID PROTOTYPING IN AEROSPACE INDUSTRY -A REVIEW

    OpenAIRE

    Vineet Kumar Vashishtha,; Rahul Makade,; Neeraj Mehla

    2011-01-01

    Rapid prototyping technology have emerged a new innovation to reduced the time cost of moulds fabrication by creating 3D product directly from computer aided design thus the designer is able to perform design validation and accuracy analysis easily in a virtual environment as if using a physical model. The primary aim of this paper is to give the reader an overview of the current state of the art in rapid prototyping technology .The paper also deal with feature’s of rapid prototyping in Aeros...

  19. How Rapid is Rapid Prototyping? Analysis of ESPADON Programme Results

    Directory of Open Access Journals (Sweden)

    Ian D. Alston

    2003-05-01

    Full Text Available New methodologies, engineering processes, and support environments are beginning to emerge for embedded signal processing systems. The main objectives are to enable defence industry to field state-of-the-art products in less time and with lower costs, including retrofits and upgrades, based predominately on commercial off the shelf (COTS components and the model-year concept. One of the cornerstones of the new methodologies is the concept of rapid prototyping. This is the ability to rapidly and seamlessly move from functional design to the architectural design to the implementation, through automatic code generation tools, onto real-time COTS test beds. In this paper, we try to quantify the term “rapid” and provide results, the metrics, from two independent benchmarks, a radar and sonar beamforming application subset. The metrics show that the rapid prototyping process may be sixteen times faster than a conventional process.

  20. Rapid prototyping using CBCT: an initial experience

    International Nuclear Information System (INIS)

    Yovchev, D.; Deliverska, E.; Indjova, J.; Ugrinov, R.

    2011-01-01

    This report presents a case of fibrous dysplasia in the left lower jaw of a 12-year-old girl, scanned with CBCT. On the basis of CBCT scan a model of affected jaw was produced using a rapid-prototyping three-dimensional printer. The case demonstrates the possibility to get a prototype by CBCT data. Prototypes can be used to support the diagnosis, planning, training (students and postgraduates) and to obtain informed consent from the patient.

  1. Customer-experienced rapid prototyping

    Science.gov (United States)

    Zhang, Lijuan; Zhang, Fu; Li, Anbo

    2008-12-01

    In order to describe accurately and comprehend quickly the perfect GIS requirements, this article will integrate the ideas of QFD (Quality Function Deployment) and UML (Unified Modeling Language), and analyze the deficiency of prototype development model, and will propose the idea of the Customer-Experienced Rapid Prototyping (CE-RP) and describe in detail the process and framework of the CE-RP, from the angle of the characteristics of Modern-GIS. The CE-RP is mainly composed of Customer Tool-Sets (CTS), Developer Tool-Sets (DTS) and Barrier-Free Semantic Interpreter (BF-SI) and performed by two roles of customer and developer. The main purpose of the CE-RP is to produce the unified and authorized requirements data models between customer and software developer.

  2. Rapid Prototyping in Orthopaedic Surgery: A User's Guide

    OpenAIRE

    Frame, Mark; Huntley, James S.

    2012-01-01

    Rapid prototyping (RP) is applicable to orthopaedic problems involving three dimensions, particularly fractures, deformities, and reconstruction. In the past, RP has been hampered by cost and difficulties accessing the appropriate expertise. Here we outline the history of rapid prototyping and furthermore a process using open-source software to produce a high fidelity physical model from CT data. This greatly mitigates the expense associated with the technique, allowing surgeons to produce pr...

  3. Rapid Prototyping Enters Mainstream Manufacturing.

    Science.gov (United States)

    Winek, Gary

    1996-01-01

    Explains rapid prototyping, a process that uses computer-assisted design files to create a three-dimensional object automatically, speeding the industrial design process. Five commercially available systems and two emerging types--the 3-D printing process and repetitive masking and depositing--are described. (SK)

  4. Rapid mask prototyping for microfluidics.

    Science.gov (United States)

    Maisonneuve, B G C; Honegger, T; Cordeiro, J; Lecarme, O; Thiry, T; Fuard, D; Berton, K; Picard, E; Zelsmann, M; Peyrade, D

    2016-03-01

    With the rise of microfluidics for the past decade, there has come an ever more pressing need for a low-cost and rapid prototyping technology, especially for research and education purposes. In this article, we report a rapid prototyping process of chromed masks for various microfluidic applications. The process takes place out of a clean room, uses a commercially available video-projector, and can be completed in less than half an hour. We quantify the ranges of fields of view and of resolutions accessible through this video-projection system and report the fabrication of critical microfluidic components (junctions, straight channels, and curved channels). To exemplify the process, three common devices are produced using this method: a droplet generation device, a gradient generation device, and a neuro-engineering oriented device. The neuro-engineering oriented device is a compartmentalized microfluidic chip, and therefore, required the production and the precise alignment of two different masks.

  5. Study of electroless nickel plating on PerFactoryTM rapid prototype model

    OpenAIRE

    J.C. Rajaguru; C. Au, M. Duke

    2012-01-01

    This paper presents an investigation of electroless nickel plating on PerFactoryTM rapid prototype model built on PerFactoryTM R05 material. PerFactoryTM R05 is acrylic based photo sensitive resin. It is a popular material in rapid prototyping using PerFactoryTM method which employs addictive manufacturing technique to build prototypes for visual inspection, assembly etc. Metallization of such a prototype can extend the application envelop of the rapid prototyping technique as they can be use...

  6. A Rapid Prototyping Environment for Wireless Communication Embedded Systems

    Directory of Open Access Journals (Sweden)

    Bryan A. Jones

    2003-05-01

    Full Text Available This paper introduces a rapid prototyping methodology which overcomes important barriers in the design and implementation of digital signal processing (DSP algorithms and systems on embedded hardware platforms, such as cellular phones. This paper describes rapid prototyping in terms of a simulation/prototype bridge and in terms of appropriate language design. The simulation/prototype bridge combines the strengths of simulation and of prototyping, allowing the designer to develop and evaluate next-generation communications systems, partly in simulation on a host computer and partly as a prototype on embedded hardware. Appropriate language design allows designers to express a communications system as a block diagram, in which each block represents an algorithm specified by a set of equations. Software tools developed for this paper implement both concepts, and have been successfully used in the development of a next-generation code division multiple access (CDMA cellular wireless communications system.

  7. Solid modeling and applications rapid prototyping, CAD and CAE theory

    CERN Document Server

    Um, Dugan

    2016-01-01

    The lessons in this fundamental text equip students with the theory of Computer Assisted Design (CAD), Computer Assisted Engineering (CAE), the essentials of Rapid Prototyping, as well as practical skills needed to apply this understanding in real world design and manufacturing settings. The book includes three main areas: CAD, CAE, and Rapid Prototyping, each enriched with numerous examples and exercises. In the CAD section, Professor Um outlines the basic concept of geometric modeling, Hermite and Bezier Spline curves theory, and 3-dimensional surface theories as well as rendering theory. The CAE section explores mesh generation theory, matrix notion for FEM, the stiffness method, and truss Equations. And in Rapid Prototyping, the author illustrates stereo lithographic theory and introduces popular modern RP technologies. Solid Modeling and Applications: Rapid Prototyping, CAD and CAE Theory is ideal for university students in various engineering disciplines as well as design engineers involved in product...

  8. Rapid prototyping model for percutaneous nephrolithotomy training.

    Science.gov (United States)

    Bruyère, Franck; Leroux, Cecile; Brunereau, Laurent; Lermusiaux, Patrick

    2008-01-01

    Rapid prototyping is a technique used for creating computer images in three dimensions more efficiently than classic techniques. Percutaneous nephrolithotomy (PCNL) is a popular method to remove kidney stones; however, broader use by the urologic community has been hampered by the morbidity associated with needle puncture to gain access to the renal calix (bleeding, pneumothorax, hydrothorax, inadvertent colon injury). A training model to improve technique and understanding of renal anatomy could improve complications related to renal puncture; however, no model currently exists for resident training. We created a training model using the rapid prototyping technique based on abdominal CT images of a patient scheduled to undergo PCNL. This allowed our staff and residents to train on the model before performing the operation. This model allowed anticipation of particular difficulties inherent to the patient's anatomy. After training, the procedure proceeded without complication, and the patient was discharged at postoperative day 1 without problems. We hypothesize that rapid prototyping could be useful for resident education, allowing the creation of numerous models for research and surgical training. In addition, we anticipate that experienced urologists could find this technique helpful in preparation for difficult PCNL operations.

  9. Rapid Prototyping Technologies for Manufacturing and Maintenance Activities

    Science.gov (United States)

    Pfeifer, Marcel Rolf

    2017-12-01

    The paper deals with the direct application of Rapid Prototyping technologies for parts and spare parts production in production companies and the economic effect by making use of this technology. Traditional production technologies are technologies such as forging, cutting, machining, etc. These technologies are widely accepted and the teething troubles are solved. Rapid Prototyping technologies such as 3D printing on the other hand came into the focus in the recent years when the technologies and the produced quality gradually advanced. Providing flexibility and time efficiency the technology should also have a practical application in production. This paper has the aim to provide a case-study based on existing cost figures to show that these technologies are not limited to prototype developments.

  10. Software testing for evolutionary iterative rapid prototyping

    OpenAIRE

    Davis, Edward V., Jr.

    1990-01-01

    Approved for public release; distribution unlimited. Rapid prototyping is emerging as a promising software development paradigm. It provides a systematic and automatable means of developing a software system under circumstances where initial requirements are not well known or where requirements change frequently during development. To provide high software quality assurance requires sufficient software testing. The unique nature of evolutionary iterative prototyping is not well-suited for ...

  11. Materials Selection and Their Characteristics as Used in Rapid Prototyping

    Science.gov (United States)

    Cooper, K.; Salvail, P.; Vesely, E.; Wells, D.

    1999-01-01

    NASA's Marshall Space Flight Center (MSFC) conducted a program to evaluate six technologies used in Rapid Prototyping (RP) to produce investment casting patterns. In this paper, RP refers to the collective additive fabrication technologies known as Solid Free-Form Fabrication. Such technologies are being used with increasing frequency in manufacturing applications, due in part to their rapidly expanding capabilities to fabricate models from many types of materials. This study used ABS plastic, polycarbonate, TrueForm PM6, epoxy resin, paper, starch, and wax. The baseline model was a semi-complex prototype fuel pump housing, intended for use in the X-33 reusable launch vehicle. All models were shelled in a production- grade colloidal silica ceramic. Primary coats were zircon-base flour with zircon backup, while secondary coats were silica grains with a tabular alumina backup. Each model was shelled in an identical manner, using the same atmospheric conditions and drying times, as well as the same number of layers. Bake-outs and firing cycles were consistent with the leach ability of each material. Preheat and bath temperatures were also kept consistent. All molds were cast in vacuum using a hydrogen-resistant superalloy (NASA- 23) that was developed in-house. The final technical evaluation included detailed measurements of the model and the final casting, in order to determine any dimensional changes caused by different pattern materials, as well as documentation of all defects and any obvious refractory/model reactions. Prototype production costs were estimated for each method and taken into consideration during trade-off analysis.

  12. Using rapid prototyping to design a smoking cessation website with end-users

    OpenAIRE

    Ronquillo, C. E.; Currie, L.; Rowsell, D.; Phillips, J. C.

    2016-01-01

    Rapid prototyping is an iterative approach to design involving cycles of prototype building, review by end-users, and refinement, and can be a valuable tool in user-centered website design. Informed by various user-centered approaches, we used rapid prototyping as a tool to collaborate with users in building a peer-support focused smoking-cessation website for gay men living with HIV. Rapid prototyping was effective in eliciting feedback on the needs of this group of potential end-users\\ud fr...

  13. Biomimetic composite coating on rapid prototyped scaffolds for bone tissue engineering.

    Science.gov (United States)

    Arafat, M Tarik; Lam, Christopher X F; Ekaputra, Andrew K; Wong, Siew Yee; Li, Xu; Gibson, Ian

    2011-02-01

    The objective of this present study was to improve the functional performance of rapid prototyped scaffolds for bone tissue engineering through biomimetic composite coating. Rapid prototyped poly(ε-caprolactone)/tri-calcium phosphate (PCL/TCP) scaffolds were fabricated using the screw extrusion system (SES). The fabricated PCL/TCP scaffolds were coated with a carbonated hydroxyapatite (CHA)-gelatin composite via biomimetic co-precipitation. The structure of the prepared CHA-gelatin composite coating was studied by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy. Compressive mechanical testing revealed that the coating process did not have any detrimental effect on the mechanical properties of the scaffolds. The cell-scaffold interaction was studied by culturing porcine bone marrow stromal cells (BMSCs) on the scaffolds and assessing the proliferation and bone-related gene and protein expression capabilities of the cells. Confocal laser microscopy and SEM images of the cell-scaffold constructs showed a uniformly distributed cell sheet and accumulation of extracellular matrix in the interior of CHA-gelatin composite-coated PCL/TCP scaffolds. The proliferation rate of BMSCs on CHA-gelatin composite-coated PCL/TCP scaffolds was about 2.3 and 1.7 times higher than that on PCL/TCP scaffolds and CHA-coated PCL/TCP scaffolds, respectively, by day 10. Furthermore, reverse transcription polymerase chain reaction and Western blot analysis revealed that CHA-gelatin composite-coated PCL/TCP scaffolds stimulate osteogenic differentiation of BMSCs the most, compared with PCL/TCP scaffolds and CHA-coated PCL/TCP scaffolds. These results demonstrate that CHA-gelatin composite-coated rapid prototyped PCL/TCP scaffolds are promising for bone tissue engineering. Copyright © 2010 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  14. Rapid Prototyping in Orthopaedic Surgery: A User's Guide

    Science.gov (United States)

    Frame, Mark; Huntley, James S.

    2012-01-01

    Rapid prototyping (RP) is applicable to orthopaedic problems involving three dimensions, particularly fractures, deformities, and reconstruction. In the past, RP has been hampered by cost and difficulties accessing the appropriate expertise. Here we outline the history of rapid prototyping and furthermore a process using open-source software to produce a high fidelity physical model from CT data. This greatly mitigates the expense associated with the technique, allowing surgeons to produce precise models for preoperative planning and procedure rehearsal. We describe the method with an illustrative case. PMID:22666160

  15. Rapid Prototyping: Technologies, Materials and Advances

    Directory of Open Access Journals (Sweden)

    Dudek P.

    2016-06-01

    Full Text Available In the context of product development, the term rapid prototyping (RP is widely used to describe technologies which create physical prototypes directly from digital data. Recently, this technology has become one of the fastest-growing methods of manufacturing parts. The paper provides brief notes on the creation of composites using RP methods, such as stereolithography, selective laser sintering or melting, laminated object modelling, fused deposition modelling or three-dimensional printing. The emphasis of this work is on the methodology of composite fabrication and the variety of materials used in these technologies.

  16. Using Rapid Prototyping to Design a Smoking Cessation Website with End-Users.

    Science.gov (United States)

    Ronquillo, Charlene; Currie, Leanne; Rowsell, Derek; Phillips, J Craig

    2016-01-01

    Rapid prototyping is an iterative approach to design involving cycles of prototype building, review by end-users and refinement, and can be a valuable tool in user-centered website design. Informed by various user-centered approaches, we used rapid prototyping as a tool to collaborate with users in building a peer-support focused smoking-cessation website for gay men living with HIV. Rapid prototyping was effective in eliciting feedback on the needs of this group of potential end-users from a smoking cessation website.

  17. Use of rapid prototyping in prosthetic auricular restoration.

    Science.gov (United States)

    Turgut, Gursel; Sacak, Bulent; Kiran, Kazim; Bas, Lutfu

    2009-03-01

    Reconstructing auricular defects is a challenging task for facial reconstructive surgeons. Although autologous reconstruction is the first choice for reconstruction, there may be circumstances of inconvenience such as previously attempted surgery, radiotherapy, systemic conditions, or patient's wish. Auricular restorations with facial prosthesis have produced promising results, but there are still problems to be tackled for improved results. Rapid prototyping in the production of an auricular prosthesis uses the mirror image of contralateral ear and produces excellent forms, eliminating the subjective perception of the prosthodontist. Rapid prototyping also lowers the production costs by reducing the need for several sessions in the process of producing the prostheses. Between 2004 and 2007, 10 patients applied to our department with the absence of an ear on a single side. All patients were male, with an average age of 23.1 years. The etiology for the loss of the ear was mostly tumors, followed by congenital deformities and trauma, respectively. In this study, we present our application of rapid prototyping technique and report our case series of 10 patients, two of which are presented in detail.

  18. Simulation and Rapid Prototyping of Adaptive Control Systems using the Adaptive Blockset for Simulink

    DEFF Research Database (Denmark)

    Ravn, Ole

    1998-01-01

    The paper describes the design considerations and implementational aspects of the Adaptive Blockset for Simulink which has been developed in a prototype implementation. The concept behind the Adaptive Blockset for Simulink is to bridge the gap between simulation and prototype controller implement...... design, controller and state variable filter.The use of the Adaptive Blockset is demonstrated using a simple laboratory setup. Both the use of the blockset for simulation and for rapid prototyping of a real-time controller are shown.......The paper describes the design considerations and implementational aspects of the Adaptive Blockset for Simulink which has been developed in a prototype implementation. The concept behind the Adaptive Blockset for Simulink is to bridge the gap between simulation and prototype controller...... implementation. This is done using the code generation capabilities of Real Time Workshop in combination with C s-function blocks for adaptive control in Simulink. In the paper the design of each group of blocks normally found in adaptive controllers is outlined. The block types are, identification, controller...

  19. Advanced Propulsion and TPS for a Rapidly-Prototyped CEV

    Science.gov (United States)

    Hudson, Gary C.

    2005-02-01

    Transformational Space Corporation (t/Space) is developing for NASA the initial designs for the Crew Exploration Vehicle family, focusing on a Launch CEV for transporting NASA and civilian passengers from Earth to orbit. The t/Space methodology is rapid prototyping of major vehicle systems, and deriving detailed specifications from the resulting hardware, avoiding "written-in-advance" specs that can force the costly invention of new capabilities simply to meet such specs. A key technology shared by the CEV family is Vapor Pressurized propulsion (Vapak) for simplicity and reliability, which provides electrical power, life support gas and a heat sink in addition to propulsion. The CEV family also features active transpiration cooling of re-entry surfaces (for reusability) backed up by passive thermal protection.

  20. Rapid Prototyping and its Application in Dentistry

    Directory of Open Access Journals (Sweden)

    V. N. V. Madhav

    2013-01-01

    Full Text Available Medical implants and biological models have three main characteristics: low volume, complex shape, and can be customized. These characteristics suit very well with Rapid Prototyping (RP and Rapid Manufacturing (RM processes. RP/RM processes are fabricated part layer- by-layer until complete shape finished from 3D model. Biocompatible materials, such as Titanium and Titanium alloy, Zirconium, Cobalt Chromium, PEEK, etc, are used for fabrication process. Reverse Engineering (RE technology greatly affects RP/RM processes. RE is used to capture or scan image of the limb, cranium, tooth, and other biological objects. Three common methods to get the image are 3D laser scanning, Computer Tomography (CT, and Magnetic Resonance Imaging (MRI. Main RP/RM techniques used in Dentistry are Stereotype Lithography Apparatus (SLA, Fused Deposition Modeling (FDM, Selective Laser Sintering (SLS, and ink jet printing. This article reviews the changing scenario of technology in dentistry with special emphasis on Rapid Prototyping and its various applications in Dentistry.

  1. Characteristics of products generated by selective sintering and stereolithography rapid prototyping processes

    Science.gov (United States)

    Cariapa, Vikram

    1993-01-01

    The trend in the modern global economy towards free market policies has motivated companies to use rapid prototyping technologies to not only reduce product development cycle time but also to maintain their competitive edge. A rapid prototyping technology is one which combines computer aided design with computer controlled tracking of focussed high energy source (eg. lasers, heat) on modern ceramic powders, metallic powders, plastics or photosensitive liquid resins in order to produce prototypes or models. At present, except for the process of shape melting, most rapid prototyping processes generate products that are only dimensionally similar to those of the desired end product. There is an urgent need, therefore, to enhance the understanding of the characteristics of these processes in order to realize their potential for production. Currently, the commercial market is dominated by four rapid prototyping processes, namely selective laser sintering, stereolithography, fused deposition modelling and laminated object manufacturing. This phase of the research has focussed on the selective laser sintering and stereolithography rapid prototyping processes. A theoretical model for these processes is under development. Different rapid prototyping sites supplied test specimens (based on ASTM 638-84, Type I) that have been measured and tested to provide a data base on surface finish, dimensional variation and ultimate tensile strength. Further plans call for developing and verifying the theoretical models by carefully designed experiments. This will be a joint effort between NASA and other prototyping centers to generate a larger database, thus encouraging more widespread usage by product designers.

  2. Rapid prototyping and stereolithography in dentistry

    Science.gov (United States)

    Nayar, Sanjna; Bhuminathan, S.; Bhat, Wasim Manzoor

    2015-01-01

    The word rapid prototyping (RP) was first used in mechanical engineering field in the early 1980s to describe the act of producing a prototype, a unique product, the first product, or a reference model. In the past, prototypes were handmade by sculpting or casting, and their fabrication demanded a long time. Any and every prototype should undergo evaluation, correction of defects, and approval before the beginning of its mass or large scale production. Prototypes may also be used for specific or restricted purposes, in which case they are usually called a preseries model. With the development of information technology, three-dimensional models can be devised and built based on virtual prototypes. Computers can now be used to create accurately detailed projects that can be assessed from different perspectives in a process known as computer aided design (CAD). To materialize virtual objects using CAD, a computer aided manufacture (CAM) process has been developed. To transform a virtual file into a real object, CAM operates using a machine connected to a computer, similar to a printer or peripheral device. In 1987, Brix and Lambrecht used, for the first time, a prototype in health care. It was a three-dimensional model manufactured using a computer numerical control device, a type of machine that was the predecessor of RP. In 1991, human anatomy models produced with a technology called stereolithography were first used in a maxillofacial surgery clinic in Viena. PMID:26015715

  3. Rapid prototyping and stereolithography in dentistry.

    Science.gov (United States)

    Nayar, Sanjna; Bhuminathan, S; Bhat, Wasim Manzoor

    2015-04-01

    The word rapid prototyping (RP) was first used in mechanical engineering field in the early 1980s to describe the act of producing a prototype, a unique product, the first product, or a reference model. In the past, prototypes were handmade by sculpting or casting, and their fabrication demanded a long time. Any and every prototype should undergo evaluation, correction of defects, and approval before the beginning of its mass or large scale production. Prototypes may also be used for specific or restricted purposes, in which case they are usually called a preseries model. With the development of information technology, three-dimensional models can be devised and built based on virtual prototypes. Computers can now be used to create accurately detailed projects that can be assessed from different perspectives in a process known as computer aided design (CAD). To materialize virtual objects using CAD, a computer aided manufacture (CAM) process has been developed. To transform a virtual file into a real object, CAM operates using a machine connected to a computer, similar to a printer or peripheral device. In 1987, Brix and Lambrecht used, for the first time, a prototype in health care. It was a three-dimensional model manufactured using a computer numerical control device, a type of machine that was the predecessor of RP. In 1991, human anatomy models produced with a technology called stereolithography were first used in a maxillofacial surgery clinic in Viena.

  4. Manufacturing of ceramic microcomponents by a rapid prototyping process chain

    International Nuclear Information System (INIS)

    Knitter, R.; Bauer, W.; Goehring, D.; Hausselt, J.

    2001-01-01

    Manufacturing of new ceramic components may be improved significantly by the use of rapid prototyping processes especially in the development of miniaturized or micropatterned components. Most known generative ceramic molding processes do not provide a sufficient resolution for the fabrication of microstructured components. In contrast to this, a rapid prototyping process chain that for example, combines micro-stereolithography and low-pressure injection molding, allows the rapid manufacturing of ceramic microcomponents from functional models to preliminary or small-lot series. (orig.)

  5. Integrating Rapid Prototyping into Graphic Communications

    Science.gov (United States)

    Xu, Renmei; Flowers, Jim

    2015-01-01

    Integrating different science, technology, engineering, and mathematics (STEM) areas can help students learn and leverage both the equipment and expertise at a single school. In comparing graphic communications classes with classes that involve rapid prototyping (RP) technologies like 3D printing, there are sufficient similarities between goals,…

  6. CO2 Laser-Based Rapid Prototyping of Micropumps

    Directory of Open Access Journals (Sweden)

    Zachary Strike

    2018-05-01

    Full Text Available The fabrication of microdevices for fluidic control often requires the use of flexible diaphragms in a way that requires cleanroom equipment and compromises performance. We use a CO 2 laser to perform the standard ablative techniques of cutting and engraving materials, but we also apply a method that we call laser placement. This allows us to fabricate precisely-positioned and precisely-sized, isolated diaphragms. This in turn enables the rapid prototyping of integrated multilayer microfluidic devices to form complex structures without the need for manual positioning or cleanroom equipment. The fabrication process is also remarkably rapid and capable of being scaled to manufacturing levels of production. We explore the use of these devices to construct a compact system of peristaltic pumps that can form water in oil droplets without the use of the non-pulsatile pumping systems typically required. Many devices can be fabricated at a time on a sheet by sheet basis with a fabrication process that, to our knowledge, is the fastest reported to date for devices of this type (requiring only 3 h. Moreover, this system is unusually compact and self-contained.

  7. Towards rapid prototyped convective microfluidic DNA amplification platform

    Science.gov (United States)

    Ajit, Smrithi; Praveen, Hemanth Mithun; Puneeth, S. B.; Dave, Abhishek; Sesham, Bharat; Mohan, K. N.; Goel, Sanket

    2017-02-01

    Today, Polymerase Chain Reaction (PCR) based DNA amplification plays an indispensable role in the field of biomedical research. Its inherent ability to exponentially amplify sample DNA has proven useful for the identification of virulent pathogens like those causing Multiple Drug-Resistant Tuberculosis (MDR-TB). The intervention of Microfluidics technology has revolutionized the concept of PCR from being a laborious and time consuming process into one that is faster, easily portable and capable of being multifunctional. The Microfluidics based PCR outweighs its traditional counterpart in terms of flexibility of varying reaction rate, operation simplicity, need of a fraction of volume and capability of being integrated with other functional elements. The scope of the present work involves the development of a real-time continuous flow microfluidic device, fabricated by 3D printing-governed rapid prototyping method, eventually leading to an automated and robust platform to process multiple DNA samples for detection of MDRTB-associated mutations. The thermal gradient characteristic to the PCR process is produced using peltier units appropriate to the microfluidic environment fully monitored and controlled by a low cost controller driven by a Data Acquisition System. The process efficiency achieved in the microfluidic environment in terms of output per cycle is expected to be on par with the traditional PCR and capable of earning the additional advantages of being faster and minimizing the handling.

  8. Utilizing Rapid Prototyping for Architectural Modeling

    Science.gov (United States)

    Kirton, E. F.; Lavoie, S. D.

    2006-01-01

    This paper will discuss our approach to, success with and future direction in rapid prototyping for architectural modeling. The premise that this emerging technology has broad and exciting applications in the building design and construction industry will be supported by visual and physical evidence. This evidence will be presented in the form of…

  9. Numerical modelling of laser rapid prototyping by fusion wire deposit

    OpenAIRE

    Arbaoui , Larbi; Masse , J.E.; Barrallier , Laurent; Mocellin , Katia

    2010-01-01

    International audience; A finite element model has been developed to simulate an innovative laser rapid prototyping process. Several numerical developments have been implemented in order to simulate the main steps of the rapid prototyping process: injection, heating, phase change and deposit. The numerical model also takes into account different phenomena: surface tension in the liquid state, asborptivity and plasma effects during materiallaser interaction. The threedimensional model is based...

  10. A computational tool for the rapid design and prototyping of propellers for underwater vehicles

    OpenAIRE

    D'Epagnier, Kathryn Port.

    2007-01-01

    An open source, MATLAB (trademarked)-based propeller design code MPVL was improved to include rapid prototyping capabilities as well as other upgrades as part of this effort. The resulting code, OpenPVL is described in this thesis. In addition, results from the development code BasicPVL are presented. An intermediate code, BasicPVL, was created by the author while OpenPVL was under development, and it provides guidance for initial propeller designs and propeller efficiency analysis. OpenPVL i...

  11. Pen-on-paper strategy for point-of-care testing: Rapid prototyping of fully written microfluidic biosensor.

    Science.gov (United States)

    Li, Zedong; Li, Fei; Xing, Yue; Liu, Zhi; You, Minli; Li, Yingchun; Wen, Ting; Qu, Zhiguo; Ling Li, Xiao; Xu, Feng

    2017-12-15

    Paper-based microfluidic biosensors have recently attracted increasing attentions in point-of-care testing (POCT) territories benefiting from their affordable, accessible and eco-friendly features, where technologies for fabricating such biosensors are preferred to be equipment free, easy-to-operate and capable of rapid prototyping. In this work, we developed a pen-on-paper (PoP) strategy based on two custom-made pens, i.e., a wax pen and a conductive-ink pen, to fully write paper-based microfluidic biosensors through directly writing both microfluidic channels and electrodes. Particularly, the proposed wax pen is competent to realize one-step fabrication of wax channels on paper, as the melted wax penetrates into paper during writing process without any post-treatments. The practical applications of the fabricated paper-based microfluidic biosensors are demonstrated by both colorimetric detection of Salmonella typhimurium DNA with detection limit of 1nM and electrochemical measurement of glucose with detection limit of 1mM. The developed PoP strategy for making microfluidic biosensors on paper characterized by true simplicity, prominent portability and excellent capability for rapid prototyping shows promising prospect in POCT applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Ceramic microfabrication by rapid prototyping process chains

    Indian Academy of Sciences (India)

    Ceramic microfabrication by rapid prototyping process chains ... is nearly impossible, shaping has to be done by a replication step in the green, unfired state. ... This process chain combines the fast and inexpensive supply of master models by ...

  13. Rapid prototyping: An innovative technique in dentistry

    Directory of Open Access Journals (Sweden)

    Shakeba Quadri

    2017-01-01

    Full Text Available Emergence of advanced digital technology has opened up new perspectives for design and production in the field of dentistry. Rapid prototyping (RP is a technique to quickly and automatically construct a three-dimensional (3D model of a part or product using 3D printers or stereolithography machines. RP has various dental applications, such as fabrication of implant surgical guides, zirconia prosthesis and molds for metal castings, maxillofacial prosthesis and frameworks for fixed and removable partial dentures, wax patterns for the dental prosthesis and complete denture. Rapid prototyping presents fascinating opportunities, but the process is difficult as it demands a high level of artistic skill, which means that the dental technicians should be able to work with the models obtained after impression to form a mirror image and achieve good esthetics. This review aims to focus on various RP methods and its application in dentistry.

  14. Expectation of rapid prototyping; Rapiddo/puroto taipingu gijutsu no tenbo

    Energy Technology Data Exchange (ETDEWEB)

    Kishinami, T. [Hokkaido Univ., Sapporo (Japan). Faculty of Engineering

    1997-04-05

    Prototyping can be defined as the physical and imaginable product model formation process used for verification of production guideline of functional component. Rapid prototyping means the combination of technology forming directly the physical model from CAD data. It is a summarization of technology composed of design assistant technology, model production technology, and integration technology. In 1980`s, 3D System Corp. proposed the stereo lithography. Since then its research and development were promptly carried out as for the technology of rapid formation o physical model. Resultantly, it became possible to fabricate the model designed by the three dimensional CAD within a day using a rapid prototyping system. This can be roughly divided into the following three: (1) stereo lithography, (2) method of melting and hardening by laser irradiation of the powder plastic and wax, (3) 3D-printing method consisting of selectively coating of ceramic powder with binder. 4 refs., 3 figs.

  15. Relatively Inexpensive Rapid Prototyping of Small Parts

    Science.gov (United States)

    Swan, Scott A.

    2003-01-01

    Parts with complex three-dimensional shapes and with dimensions up to 8 by 8 by 10 in. (20.3 by 20.3 by 25.4 cm) can be made as unitary pieces of a room-temperature-curing polymer, with relatively little investment in time and money, by a process now in use at Johnson Space Center. The process is one of a growing number of processes and techniques that are known collectively as the art of rapid prototyping. The main advantages of this process over other rapid-prototyping processes are greater speed and lower cost: There is no need to make paper drawings and take them to a shop for fabrication, and thus no need for the attendant paperwork and organizational delays. Instead, molds for desired parts are made automatically on a machine that is guided by data from a computer-aided design (CAD) system and can reside in an engineering office.

  16. Classroom Evaluation of a Rapid Prototyping System.

    Science.gov (United States)

    Tennyson, Stephen A.; Krueger, Thomas J.

    2001-01-01

    Introduces rapid prototyping which creates virtual models through a variety of automated material additive processes. Relates experiences using JP System 5 in freshman and sophomore engineering design graphics courses. Analyzes strengths and limitations of the JP System 5 and discusses how to use it effectively. (Contains 15 references.)…

  17. Habitat Demonstration Unit Project: Leadership and Management Strategies for a Rapid Prototyping Project

    Science.gov (United States)

    Kennedy, Kriss J.; Toup, Larry; Gill, Tracy; Tri, Terry; Howe, Scott; Smitherman, David

    2011-01-01

    This paper gives an overview of the National Aeronautics and Space Administration (NASA) led multi-center Habitat Demonstration Unit (HDU) project leadership and management strategies being used by the NASA HDU team for a rapid prototyping project. The HDU project team constructed and tested an analog prototype lunar surface habitat/laboratory called the Pressurized Excursion Module (PEM) during 2010. The prototype unit subsystems were integrated in a short amount of time, utilizing a tiger team rapid prototyping approach that brought together over 20 habitation-related technologies and innovations from a variety of NASA centers. This paper describes the leadership and management strategies as well as lessons learned pertaining to leading and managing a multi-center diverse team in a rapid prototype environment. The PEM configuration went from a paper design to an operational surface habitat demonstration unit in less than 12 months. The HDU project is part of the strategic plan from the Exploration Systems Mission Directorate (ESMD) Directorate Integration Office (DIO) and the Exploration Mission Systems Office (EMSO) to test destination elements in analog environments. The 2011 HDU-Deep Space Habitat (DSH) configuration will build upon the PEM work, and emphasize validity of crew operations (remote working and living), EVA operations, mission operations, logistics operations, and science operations that might be required in a deep space context for Near Earth Object (NEO) exploration mission architectures. The 2011 HDU-DSH will be field-tested during the 2011 Desert Research and Technologies Studies (DRaTS) field tests. The HDU project is a "technology-pull" project that integrates technologies and innovations from multiple NASA centers. This project will repurpose the HDU 2010 demo unit that was field tested in the 2010 DRaTS, adding habitation functionality to the prototype unit. This paper will describe the strategy of establishing a multi-center project

  18. Manufacturing implant supported auricular prostheses by rapid prototyping techniques.

    Science.gov (United States)

    Karatas, Meltem Ozdemir; Cifter, Ebru Demet; Ozenen, Didem Ozdemir; Balik, Ali; Tuncer, Erman Bulent

    2011-08-01

    Maxillofacial prostheses are usually fabricated on the models obtained following the impression procedures. Disadvantages of conventional impression techniques used in production of facial prosthesis are deformation of soft tissues caused by impression material and disturbance of the patient due to. Additionally production of prosthesis by conventional methods takes longer time. Recently, rapid prototyping techniques have been developed for extraoral prosthesis in order to reduce these disadvantages of conventional methods. Rapid prototyping technique has the potential to simplify the procedure and decrease the laboratory work required. It eliminates the need for measurement impression procedures and preparation of wax model to be performed by prosthodontists themselves In the near future this technology will become a standard for fabricating maxillofacial prostheses.

  19. Rapid prototyping technology and its application in bone tissue engineering.

    Science.gov (United States)

    Yuan, Bo; Zhou, Sheng-Yuan; Chen, Xiong-Sheng

    Bone defects arising from a variety of reasons cannot be treated effectively without bone tissue reconstruction. Autografts and allografts have been used in clinical application for some time, but they have disadvantages. With the inherent drawback in the precision and reproducibility of conventional scaffold fabrication techniques, the results of bone surgery may not be ideal. This is despite the introduction of bone tissue engineering which provides a powerful approach for bone repair. Rapid prototyping technologies have emerged as an alternative and have been widely used in bone tissue engineering, enhancing bone tissue regeneration in terms of mechanical strength, pore geometry, and bioactive factors, and overcoming some of the disadvantages of conventional technologies. This review focuses on the basic principles and characteristics of various fabrication technologies, such as stereolithography, selective laser sintering, and fused deposition modeling, and reviews the application of rapid prototyping techniques to scaffolds for bone tissue engineering. In the near future, the use of scaffolds for bone tissue engineering prepared by rapid prototyping technology might be an effective therapeutic strategy for bone defects.

  20. Rapid prototyping technology and its application in bone tissue engineering*

    Science.gov (United States)

    YUAN, Bo; ZHOU, Sheng-yuan; CHEN, Xiong-sheng

    2017-01-01

    Bone defects arising from a variety of reasons cannot be treated effectively without bone tissue reconstruction. Autografts and allografts have been used in clinical application for some time, but they have disadvantages. With the inherent drawback in the precision and reproducibility of conventional scaffold fabrication techniques, the results of bone surgery may not be ideal. This is despite the introduction of bone tissue engineering which provides a powerful approach for bone repair. Rapid prototyping technologies have emerged as an alternative and have been widely used in bone tissue engineering, enhancing bone tissue regeneration in terms of mechanical strength, pore geometry, and bioactive factors, and overcoming some of the disadvantages of conventional technologies. This review focuses on the basic principles and characteristics of various fabrication technologies, such as stereolithography, selective laser sintering, and fused deposition modeling, and reviews the application of rapid prototyping techniques to scaffolds for bone tissue engineering. In the near future, the use of scaffolds for bone tissue engineering prepared by rapid prototyping technology might be an effective therapeutic strategy for bone defects. PMID:28378568

  1. The use of an automated flight test management system in the development of a rapid-prototyping flight research facility

    Science.gov (United States)

    Duke, Eugene L.; Hewett, Marle D.; Brumbaugh, Randal W.; Tartt, David M.; Antoniewicz, Robert F.; Agarwal, Arvind K.

    1988-01-01

    An automated flight test management system (ATMS) and its use to develop a rapid-prototyping flight research facility for artificial intelligence (AI) based flight systems concepts are described. The ATMS provides a flight test engineer with a set of tools that assist in flight planning and simulation. This system will be capable of controlling an aircraft during the flight test by performing closed-loop guidance functions, range management, and maneuver-quality monitoring. The rapid-prototyping flight research facility is being developed at the Dryden Flight Research Facility of the NASA Ames Research Center (Ames-Dryden) to provide early flight assessment of emerging AI technology. The facility is being developed as one element of the aircraft automation program which focuses on the qualification and validation of embedded real-time AI-based systems.

  2. A low cost rapid prototype platform for a three phase PFC rectifier application

    DEFF Research Database (Denmark)

    Haase, Frerk; Kouchaki, Alireza; Nymand, Morten

    2015-01-01

    In this paper the design and development of a low cost rapid prototype platform for a Three Phase PFC rectifier application is presented. The active rectifier consists of a SiC-MOSFET based PWM converter and a low cost rapid prototype platform for simulating and implementing the digital control...

  3. Rapid Prototyping of Electrically Small Spherical Wire Antennas

    DEFF Research Database (Denmark)

    Kim, Oleksiy S.

    2014-01-01

    It is shown how modern rapid prototyping technologies can be applied for quick and inexpensive, but still accurate, fabrication of electrically small wire antennas. A well known folded spherical helix antenna and a novel spherical zigzag antenna have been fabricated and tested, exhibiting...

  4. Rapid prototyping framework for robot-assisted training of autistic children

    NARCIS (Netherlands)

    Kim, Mingyu; Barakova, E.I.; Lourens, T.

    2014-01-01

    Research in uptake and actual use of robots in socially assistive tasks is rapidly growing. However, practical applications lack behind due to the enormous effort to create meaningful behaviours. This paper describes a rapid prototyping framework for robot-assisted training of children with Autism

  5. The scope of application of incremental rapid prototyping methods in foundry engineering

    Directory of Open Access Journals (Sweden)

    M. Stankiewicz

    2010-01-01

    Full Text Available The article presents the scope of application of selected incremental Rapid Prototyping methods in the process of manufacturing casting models, casting moulds and casts. The Rapid Prototyping methods (SL, SLA, FDM, 3DP, JS are predominantly used for the production of models and model sets for casting moulds. The Rapid Tooling methods, such as: ZCast-3DP, ProMetalRCT and VoxelJet, enable the fabrication of casting moulds in the incremental process. The application of the RP methods in cast production makes it possible to speed up the prototype preparation process. This is particularly vital to elements of complex shapes. The time required for the manufacture of the model, the mould and the cast proper may vary from a few to several dozen hours.

  6. Rapid Prototyping of Tangibles with a Capacitive Mouse

    DEFF Research Database (Denmark)

    Ramos, Juan David Hincapie; Esbensen, Morten; Kogutowska, Magdalena

    2011-01-01

    lays the capacitive surface and communication capa- bilities of a Microsoft TouchMouse, both of which are ap- propriated to fulfill the mentined requirements. Unlike ex- isting approaches for rapid prototyping of tangibles like the Arduino boards, using the Toki toolkit does not require de- velopers...

  7. Design and prototype of an augmented reality display with per-pixel mutual occlusion capability.

    Science.gov (United States)

    Wilson, Austin; Hua, Hong

    2017-11-27

    State-of-the-art optical see-through head-mounted displays for augmented reality (AR) applications lack mutual occlusion capability, which refers to the ability to render correct light blocking relationship when merging digital and physical objects, such that the virtual views appear to be ghost-like and lack realistic appearance. In this paper, using off-the-shelf optical components, we present the design and prototype of an AR display which is capable of rendering per-pixel mutual occlusion. Our prototype utilizes a miniature organic light emitting display coupled with a liquid crystal on silicon type spatial light modulator to achieve an occlusion capable AR display offering a 30° diagonal field of view and an angular resolution of 1.24 arcminutes, with an optical performance of > 0.4 contrast over the full field at the Nquist frequency of 24.2 cycles/degree. We experimentally demonstrate a monocular prototype achieving >100:1 dynamic range in well-lighted environments.

  8. Using 3D Printing for Rapid Prototyping of Characterization Tools for Investigating Powder Blend Behavior

    DEFF Research Database (Denmark)

    Hirschberg, Cosima; Boetker, Johan P; Rantanen, Jukka

    2018-01-01

    of complex powder behavior, such as mixing process and segregation phenomenon. An approach based on the fast prototyping of new powder handling geometries and interfacing solutions for process analytical tools is reported. This study utilized 3D printing for rapid prototyping of customized geometries...... the percolation thresholds. Blends with a paracetamol wt% above the percolation threshold were subsequently investigated in relation to their segregation behavior. Rapid prototyping using 3D printing allowed designing two funnels with tailored flow behavior (funnel flow) of model formulations, which could...... blend were monitored during blending. Rapid prototyping allowed for fast modification of powder testing geometries and easy interfacing with process analytical tools, opening new possibilities for more detailed powder characterization....

  9. Low-Cost Rotating Experimentation in Compressor Aerodynamics Using Rapid Prototyping

    Directory of Open Access Journals (Sweden)

    Mathias Michaud

    2016-01-01

    Full Text Available With the rapid evolution of additive manufacturing, 3D printed parts are no longer limited to display purposes but can also be used in structural applications. The objective of this paper is to show that 3D prototyping can be used to produce low-cost rotating turbomachinery rigs capable of carrying out detailed flow measurements that can be used, among other things, for computational fluid dynamics (CFD code validation. A fully instrumented polymer two-stage axial-mixed flow compressor test rig was designed and fabricated with stereolithography (SLA technology by a team of undergraduate students as part of a senior-year design course. Experiments were subsequently performed on this rig to obtain both the overall pressure rise characteristics of the compressor and the stagnation pressure distributions downstream of the blade rows for comparison with CFD simulations. In doing so, this work provides a first-of-a-kind assessment of the use of polymer additive technology for low-cost rotating turbomachinery experimentation with detailed measurements.

  10. Rapid Prototyping High-Performance MR Safe Pneumatic Stepper Motors

    NARCIS (Netherlands)

    Groenhuis, Vincent; Stramigioli, Stefano

    2018-01-01

    In this paper we show that pneumatic stepper motors for MR safe robots can be constructed using rapid prototyping techniques such as 3-D printing and laser-cutting. The designs are lightweight, completely metal-free and fully customizable. Besides MR safe robotic systems, other potential

  11. Rapid prototyping of complete systems, the case study of a smart parking

    OpenAIRE

    Ducreux , Laurent-Frédéric; Guyon-Gardeux , Claire; Louvel , Maxime; Pacull , François; Safietou Raby , Thior; Vergara-Gallego , Maria Isabel

    2015-01-01

    International audience; This paper details how LINC a coordination middle-ware, can fasten the development of prototypes that integrate several equipment. A case study of rapid prototyping is presented. It illustrates how a smart parking prototype has been built from several independent and autonomous equipment, coming from different vendors. This has been achieved by parallel development thanks to the resource based approach offered by LINC. This paper also describes how LINC helps building ...

  12. ModGrasp: An open-source rapid-prototyping framework for designing low-cost sensorised modular hands

    OpenAIRE

    Sanfilippo, Filippo; Zhang, Houxiang; Pettersen, Kristin Ytterstad; Salvietti, G.; Prattichizzo, Domenico

    2014-01-01

    This paper introduces ModGrasp, an open-source virtual and physical rapid-prototyping framework that allows for the design, simulation and control of low-cost sensorised modular hands. By combining the rapid-prototyping approach with the modular concept, different manipulator configurations can be modelled. A real-time one-to-one correspondence between virtual and physical prototypes is established. Different control algorithms can be implemented for the models. By using a low-cost sensing ap...

  13. Rapid control prototyping - new technologies and tools; Rapid Control Prototyping - neue Moeglichkeiten und Werkzeuge

    Energy Technology Data Exchange (ETDEWEB)

    Otterbach, R.; Eckmann, M.; Mertens, F. [dSPACE GmbH, Paderborn (Germany)

    2004-06-01

    The paper presents the status quo in rapid control prototyping (RCP) and discusses further developments of this technology. The complete functional chain, from sensors to data preprocessing and the real-time processor, right through to control of the actuators, is created as an integrated hardware and software solution. The greatest flexibility and configurability are achieved with a modular platform concept that includes signal conditioning and power stages. The architecture of modern microcontrollers and electronic control units (ECUs) result in new requirements in the field of bypassing. These are fulfilled by appropriate solutions based on on-chip debug interfaces and standardized data protocols on serial busses. RCP support for developing networked, time-triggered vehicle systems, and the particular requirements for the tool environment, are described using FlexRay as an example. (orig.)

  14. Removable partial dentures: use of rapid prototyping.

    Science.gov (United States)

    Lima, Julia Magalhaes Costa; Anami, Lilian Costa; Araujo, Rodrigo Maximo; Pavanelli, Carlos A

    2014-10-01

    The CAD/CAM technology associated with rapid prototyping (RP) is already widely used in the fabrication of all-ceramic fixed prostheses and in the biomedical area; however, the use of this technology for the manufacture of metal frames for removable dentures is new. This work reports the results of a literature review conducted on the use of CAD/CAM and RP in the manufacture of removable partial dentures. © 2014 by the American College of Prosthodontists.

  15. Rapid Prototyping 3D Model in Treatment of Pediatric Hip Dysplasia: A Case Report.

    Science.gov (United States)

    Holt, Andrew M; Starosolski, Zbigniew; Kan, J Herman; Rosenfeld, Scott B

    2017-01-01

    Rapid prototyping is an emerging technology that integrates common medical imaging with specialized production mechanisms to create detailed anatomic replicas. 3D-printed models of musculoskeletal anatomy have already proven useful in orthopedics and their applications continue to expand. We present the case of a 10 year-old female with Down syndrome and left acetabular dysplasia and chronic hip instability who underwent periacetabular osteotomy. A rapid prototyping 3D model was created to better understand the anatomy, counsel the family about the problem and the surgical procedure, as well as guide surgical technique. The intricate detail and size match of the model with the patient's anatomy offered unparalleled, hands-on experience with the patient's anatomy pre-operatively and improved surgical precision. Our experience with rapid prototyping confirmed its ability to enhance orthopedic care by improving the surgeon's ability to understand complex anatomy. Additionally, we report a new application utilizing intraoperative fluoroscopic comparison of the model and patient to ensure surgical precision and minimize the risk of complications. This technique could be used in other challenging cases. The increasing availability of rapid prototyping welcomes further use in all areas of orthopedics.

  16. Application of Rapid Prototyping Methods to High-Speed Wind Tunnel Testing

    Science.gov (United States)

    Springer, A. M.

    1998-01-01

    This study was undertaken in MSFC's 14-Inch Trisonic Wind Tunnel to determine if rapid prototyping methods could be used in the design and manufacturing of high speed wind tunnel models in direct testing applications, and if these methods would reduce model design/fabrication time and cost while providing models of high enough fidelity to provide adequate aerodynamic data, and of sufficient strength to survive the test environment. Rapid prototyping methods utilized to construct wind tunnel models in a wing-body-tail configuration were: fused deposition method using both ABS plastic and PEEK as building materials, stereolithography using the photopolymer SL-5170, selective laser sintering using glass reinforced nylon, and laminated object manufacturing using plastic reinforced with glass and 'paper'. This study revealed good agreement between the SLA model, the metal model with an FDM-ABS nose, an SLA nose, and the metal model for most operating conditions, while the FDM-ABS data diverged at higher loading conditions. Data from the initial SLS model showed poor agreement due to problems in post-processing, resulting in a different configuration. A second SLS model was tested and showed relatively good agreement. It can be concluded that rapid prototyping models show promise in preliminary aerodynamic development studies at subsonic, transonic, and supersonic speeds.

  17. [Mandibular-driven simultaneous maxillo-mandibular distraction for hemifacial microsomia with rapid prototyping technology].

    Science.gov (United States)

    Gao, Quan-Wen; Song, Hui-Feng; Xu, Ming-Huo; Liu, Chun-Ming; Chai, Jia-Ke

    2013-11-01

    To explore the clinical application of mandibular-driven simultaneous maxillo-mandihular distraction to correct hemifacial microsomia with rapid prototyping technology. The patient' s skull resin model was manufactured with rapid prototyping technology. The osteotomy was designed on skull resin model. According to the preoperative design, the patients underwent Le Fort I osteotomy and mandibular ramus osteotomy. The internal mandible distractor was embedded onto the osteotomy position. The occlusal titanium pin was implanted. Distraction were carried out by mandibular-driven simultaneous maxillo-mandihular distraction 5 days after operation. The distraction in five patients was complete as designed. No infection and dysosteogenesis happened. The longest distance of distraction was 28 mm, and the shortest distance was 16 mm. The facial asymmetry deformity was significantly improved at the end of distraction. The ocelusal plane of patients obviously improved. Rapid prototyping technology is helpful to design precisely osteotomy before operation. Mandibular-driven simultaneous maxillo-mandibular distraction can correct hemifacial microsomia. It is worth to clinical application.

  18. Rapid Prototyping — A Tool for Presenting 3-Dimensional Digital Models Produced by Terrestrial Laser Scanning

    Directory of Open Access Journals (Sweden)

    Juho-Pekka Virtanen

    2014-07-01

    Full Text Available Rapid prototyping has received considerable interest with the introduction of affordable rapid prototyping machines. These machines can be used to manufacture physical models from three-dimensional digital mesh models. In this paper, we compare the results obtained with a new, affordable, rapid prototyping machine, and a traditional professional machine. Two separate data sets are used for this, both of which were acquired using terrestrial laser scanning. Both of the machines were able to produce complex and highly detailed geometries in plastic material from models based on terrestrial laser scanning. The dimensional accuracies and detail levels of the machines were comparable, and the physical artifacts caused by the fused deposition modeling (FDM technique used in the rapid prototyping machines could be found in both models. The accuracy of terrestrial laser scanning exceeded the requirements for manufacturing physical models of large statues and building segments at a 1:40 scale.

  19. Rapid prototyping-assisted maxillofacial reconstruction.

    Science.gov (United States)

    Peng, Qian; Tang, Zhangui; Liu, Ousheng; Peng, Zhiwei

    2015-05-01

    Rapid prototyping (RP) technologies have found many uses in dentistry, and especially oral and maxillofacial surgery, due to its ability to promote product development while at the same time reducing cost and depositing a part of any degree of complexity theoretically. This paper provides an overview of RP technologies for maxillofacial reconstruction covering both fundamentals and applications of the technologies. Key fundamentals of RP technologies involving the history, characteristics, and principles are reviewed. A number of RP applications to the main fields of oral and maxillofacial surgery, including restoration of maxillofacial deformities and defects, reduction of functional bone tissues, correction of dento-maxillofacial deformities, and fabrication of maxillofacial prostheses, are discussed. The most remarkable challenges for development of RP-assisted maxillofacial surgery and promising solutions are also elaborated.

  20. Additive manufacturing technologies 3D printing, rapid prototyping, and direct digital manufacturing

    CERN Document Server

    Gibson, Ian; Stucker, Brent

    2015-01-01

    This book covers in detail the various aspects of joining materials to form parts. A conceptual overview of rapid prototyping and layered manufacturing is given,  beginning with the fundamentals so that readers can get up to speed quickly. Unusual and emerging applications such as micro-scale manufacturing, medical applications, aerospace, and rapid manufacturing are also discussed. This book provides a comprehensive overview of rapid prototyping technologies as well as support technologies such as software systems, vacuum casting, investment casting, plating, infiltration and other systems. This book also: Reflects recent developments and trends and adheres to the ASTM, SI, and other standards Includes chapters on automotive technology, aerospace technology and low-cost AM technologies Provides a broad range of technical questions to ensure comprehensive understanding of the concepts covered  

  1. Extending NASA Research Results to Benefit Society: Rapid Prototyping for Coastal Applications

    Science.gov (United States)

    Glorioso, Mark V.; Miller, Richard L.; Hall, Callie M.; McPherson, Terry R.

    2006-01-01

    The mission of the NASA Applied Sciences Program is to expand and accelerate the use of NASA research results to benefit society in 12 application areas of national priority. ONe of the program's major challenges is to perform a quick, efficient, and detailed review (i.e., prototyping) of the large number of combinations of NASA observations and results from Earth system models that may be used by a wide range of decision support tools. A Rapid Prototyping Capacity (RPC) is being developed to accelerate the use of NASA research results. Here, we present the conceptual framework of the Rapid Prototyping Capacity within the context of quickly assessing the efficacy of NASA research results and technologies to support the Coastal Management application. An initial RPC project designed to quickly evaluate the utility of moderate-resolution MODIS products for calibrating/validating coastal sediment transport models is also presented.

  2. Open-Source Wax RepRap 3-D Printer for Rapid Prototyping Paper-Based Microfluidics.

    Science.gov (United States)

    Pearce, J M; Anzalone, N C; Heldt, C L

    2016-08-01

    The open-source release of self-replicating rapid prototypers (RepRaps) has created a rich opportunity for low-cost distributed digital fabrication of complex 3-D objects such as scientific equipment. For example, 3-D printable reactionware devices offer the opportunity to combine open hardware microfluidic handling with lab-on-a-chip reactionware to radically reduce costs and increase the number and complexity of microfluidic applications. To further drive down the cost while improving the performance of lab-on-a-chip paper-based microfluidic prototyping, this study reports on the development of a RepRap upgrade capable of converting a Prusa Mendel RepRap into a wax 3-D printer for paper-based microfluidic applications. An open-source hardware approach is used to demonstrate a 3-D printable upgrade for the 3-D printer, which combines a heated syringe pump with the RepRap/Arduino 3-D control. The bill of materials, designs, basic assembly, and use instructions are provided, along with a completely free and open-source software tool chain. The open-source hardware device described here accelerates the potential of the nascent field of electrochemical detection combined with paper-based microfluidics by dropping the marginal cost of prototyping to nearly zero while accelerating the turnover between paper-based microfluidic designs. © 2016 Society for Laboratory Automation and Screening.

  3. Low-Cost Rapid Prototyping of Whole-Glass Microfluidic Devices

    Science.gov (United States)

    Yuen, Po Ki; Goral, Vasiliy N.

    2012-01-01

    A low-cost, straightforward, rapid prototyping of whole-glass microfluidic devices is presented using glass-etching cream that can be easily purchased in local stores. A self-adhered vinyl stencil cut out by a desktop digital craft cutter was used as an etching mask for patterning microstructures in glass using the glass-etching cream. A specific…

  4. A review of rapid prototyping techniques for tissue engineering purposes

    NARCIS (Netherlands)

    Peltola, Sanna M.; Melchels, Ferry P. W.; Grijpma, Dirk W.; Kellomaki, Minna

    2008-01-01

    Rapid prototyping (RP) is a common name for several techniques, which read in data from computer-aided design (CAD) drawings and manufacture automatically three-dimensional objects layer-by-layer according to the virtual design. The utilization of RP in tissue engineering enables the production of

  5. Development of Experimental Setup of Metal Rapid Prototyping Machine using Selective Laser Sintering Technique

    Science.gov (United States)

    Patil, S. N.; Mulay, A. V.; Ahuja, B. B.

    2018-04-01

    Unlike in the traditional manufacturing processes, additive manufacturing as rapid prototyping, allows designers to produce parts that were previously considered too complex to make economically. The shift is taking place from plastic prototype to fully functional metallic parts by direct deposition of metallic powders as produced parts can be directly used for desired purpose. This work is directed towards the development of experimental setup of metal rapid prototyping machine using selective laser sintering and studies the various parameters, which plays important role in the metal rapid prototyping using SLS technique. The machine structure in mainly divided into three main categories namely, (1) Z-movement of bed and table, (2) X-Y movement arrangement for LASER movements and (3) feeder mechanism. Z-movement of bed is controlled by using lead screw, bevel gear pair and stepper motor, which will maintain the accuracy of layer thickness. X-Y movements are controlled using timing belt and stepper motors for precise movements of LASER source. Feeder mechanism is then developed to control uniformity of layer thickness metal powder. Simultaneously, the study is carried out for selection of material. Various types of metal powders can be used for metal RP as Single metal powder, mixture of two metals powder, and combination of metal and polymer powder. Conclusion leads to use of mixture of two metals powder to minimize the problems such as, balling effect and porosity. Developed System can be validated by conducting various experiments on manufactured part to check mechanical and metallurgical properties. After studying the results of these experiments, various process parameters as LASER properties (as power, speed etc.), and material properties (as grain size and structure etc.) will be optimized. This work is mainly focused on the design and development of cost effective experimental setup of metal rapid prototyping using SLS technique which will gives the feel of

  6. Low-cost rapid prototyping of flexible plastic paper based microfluidic devices

    KAUST Repository

    Fan, Yiqiang; Li, Huawei; Yi, Ying; Foulds, Ian G.

    2013-01-01

    This research presents a novel rapid prototyping method for paper-based flexible microfluidic devices. The microchannels were fabricated using laser ablation on a piece of plastic paper (permanent paper), the dimensions of the microchannels

  7. Teaching Tip: Using Rapid Game Prototyping for Exploring Requirements Discovery and Modeling

    Science.gov (United States)

    Dalal, Nikunj

    2012-01-01

    We describe the use of rapid game prototyping as a pedagogic technique to experientially explore and learn requirements discovery, modeling, and specification in systems analysis and design courses. Students have a natural interest in gaming that transcends age, gender, and background. Rapid digital game creation is used to build computer games…

  8. Obtention of hydroxyapatite submicrometric of bovine origin by vibratory grinding for rapid prototyping

    International Nuclear Information System (INIS)

    Meira, C.R.; Purquerio, B.M.; Fortulan, C.A.

    2011-01-01

    Submicron bovine hydroxyapatite was obtained for rapid prototyping. Hydroxyapatite structure originated from bovine mineral bone has great importance among the biomaterials and biocompatibility due to its great similarity with the human bone structure. This study aims to obtain powder for manufacture by rapid prototyping of scaffolds. This technique manufacture requires highly reactive powders to compensate for the absence of pressure forming. Hydroxyapatite was milled in a ball mill and vibratory mill, and analyzed for their average equivalent spherical diameter and surface area. Test specimens were isostatically pressed at 100 MPa and machined into cylindrical test specimens. These specimens were sintered at several temperatures to determine the optimal sintering temperature based on densification and chemistry stability. In grinding ball mill was obtained particles of equivalent diameter of 0.74 micron in vibratory mill of 0.46 micrometers. An average flexural strength of 100 MPa and 99,8% of real density was attained for the sample sintered at 1300 deg C/2h, signaling potential for use in rapid prototyping. (author)

  9. Rapid Control Prototyping Plataform for Didactic Plant Motor DC

    Directory of Open Access Journals (Sweden)

    Cristian Bazán-Orobio

    2013-06-01

    Full Text Available In this paper a design, implementation and validation of a Rapid Control Prototype platform for a plant based on a DC motor is proposed. This low-cost prototype provides of an electronic card (with a motor DC and sensors manipulated by PC with free software tools using Linux, Scilab / Scicos and RTAI-Lab. This RCP System allows developing speed -position control trainings by using different types of PID industrial controllers with anti – wind up and bump less transfer schemes. We develop a speed control application structured in four steps: identification, controller design, simulation and real time control, where there are pedagogical advantages of a platform that not only allows simulation but also real-time control of a plant.

  10. Bio rapid prototyping by extruding/aspirating/refilling thermoreversible hydrogel

    International Nuclear Information System (INIS)

    Iwami, K; Noda, T; Ishida, K; Umeda, N; Morishima, K; Nakamura, M

    2010-01-01

    This paper reports a method for rapid prototyping of cell tissues, which is based on a system that extrudes, aspirates and refills a mixture of cells and thermoreversible hydrogel as a scaffold. In the extruding mode, a cell-mixed scaffold solution in the sol state is extruded from a cooled micronozzle into a temperature-controlled substrate, which keeps the scaffold in the gel state. In the aspiration mode, the opposite process is performed by Bernoulli suction. In the refilling mode, the solution is extruded into a groove created in the aspiration mode. The minimum width of extruded hydrogel pattern is 114 ± 15 μm by employing a nozzle of diameter 100 μm, and that of aspirated groove was 355 ± 10 μm using a 500 μm-diameter nozzle. Gum arabic is mixed with the scaffold solution to avoid peeling-off of the gel pattern from the substrate. Patterning of Sf-9 cell tissue is demonstrated, and the stability of the patterned cell is investigated. This system offers a procedure for rapid prototyping and local modification of cell scaffolds for tissue engineering.

  11. Surface quality in rapid prototype MMD process

    Directory of Open Access Journals (Sweden)

    Lisandro Vargas Henríquez

    2004-09-01

    Full Text Available This article summarises a Manufacturing Materials and Processes MSc thesis written for the Mechanical and Electrical Engineering Department. The paper shows the interaction of process, gap (deposition distance and extursion terminal velocity modelled process parameters for CEIF's (Centro de Equipos Interfacultades rapid prototype molten material deposit (MMD Titan SH-1 machine by analysing prototupes improved surface quality and resistence to tension and characterising material. The project applies experimental design criteria for orientating the selection of experimental process parameters. Acrylonitrile-buttadin-styrene (ABS had alredy been mechanically and physicochemically characterised (i.e the material used in the MMD process.

  12. High-throughput, temperature-controlled microchannel acoustophoresis device made with rapid prototyping

    DEFF Research Database (Denmark)

    Adams, Jonathan D; Ebbesen, Christian L.; Barnkob, Rune

    2012-01-01

    -slide format using low-cost, rapid-prototyping techniques. This high-throughput acoustophoresis chip (HTAC) utilizes a temperature-stabilized, standing ultrasonic wave, which imposes differential acoustic radiation forces that can separate particles according to size, density and compressibility. The device...

  13. Manufacturing Implant Supported Auricular Prostheses by Rapid Prototyping Techniques

    OpenAIRE

    Karatas, Meltem Ozdemir; Cifter, Ebru Demet; Ozenen, Didem Ozdemir; Balik, Ali; Tuncer, Erman Bulent

    2011-01-01

    Maxillofacial prostheses are usually fabricated on the models obtained following the impression procedures. Disadvantages of conventional impression techniques used in production of facial prosthesis are deformation of soft tissues caused by impression material and disturbance of the patient due to. Additionally production of prosthesis by conventional methods takes longer time. Recently, rapid prototyping techniques have been developed for extraoral prosthesis in order to reduce these disadv...

  14. The development of an autonomous rendezvous and docking simulation using rapid integration and prototyping technology

    Science.gov (United States)

    Shackelford, John H.; Saugen, John D.; Wurst, Michael J.; Adler, James

    1991-01-01

    A generic planar 3 degree of freedom simulation was developed that supports hardware in the loop simulations, guidance and control analysis, and can directly generate flight software. This simulation was developed in a small amount of time utilizing rapid prototyping techniques. The approach taken to develop this simulation tool, the benefits seen using this approach to development, and on-going efforts to improve and extend this capability are described. The simulation is composed of 3 major elements: (1) Docker dynamics model, (2) Dockee dynamics model, and (3) Docker Control System. The docker and dockee models are based on simple planar orbital dynamics equations using a spherical earth gravity model. The docker control system is based on a phase plane approach to error correction.

  15. Design Principles for Rapid Prototyping Forces Sensors using 3D Printing.

    Science.gov (United States)

    Kesner, Samuel B; Howe, Robert D

    2011-07-21

    Force sensors provide critical information for robot manipulators, manufacturing processes, and haptic interfaces. Commercial force sensors, however, are generally not adapted to specific system requirements, resulting in sensors with excess size, cost, and fragility. To overcome these issues, 3D printers can be used to create components for the quick and inexpensive development of force sensors. Limitations of this rapid prototyping technology, however, require specialized design principles. In this paper, we discuss techniques for rapidly developing simple force sensors, including selecting and attaching metal flexures, using inexpensive and simple displacement transducers, and 3D printing features to aid in assembly. These design methods are illustrated through the design and fabrication of a miniature force sensor for the tip of a robotic catheter system. The resulting force sensor prototype can measure forces with an accuracy of as low as 2% of the 10 N measurement range.

  16. TUTORIAL: Focused-ion-beam-based rapid prototyping of nanoscale magnetic devices

    Science.gov (United States)

    Khizroev, S.; Litvinov, D.

    2004-03-01

    In this tutorial, focused-ion-beam (FIB)-based fabrication is considered from a very unconventional angle. FIB is considered not as a fabrication tool that can be used for mass production of electronic devices, similar to optical and E-beam—based lithography, but rather as a powerful tool to rapidly fabricate individual nanoscale magnetic devices for prototyping future electronic applications. Among the effects of FIB-based fabrication of magnetic devices, the influence of Ga+-ion implantation on magnetic properties is presented. With help of magnetic force microscopy (MFM), it is shown that there is a critical doze of ions that a magnetic material can be exposed to without experiencing a change in the magnetic properties. Exploiting FIB from such an unconventional perspective is especially favourable today when the future of so many novel technologies depends on the ability to rapidly fabricate prototype nanoscale magnetic devices. As one of the most illustrative examples, the multi-billion-dollar data storage industry is analysed as the technology field that strongly benefited from implementing FIB in the above-described role. The essential role of FIB in the most recent trend of the industry towards perpendicular magnetic recording is presented. Moreover, other emerging and fast-growing technologies are considered as examples of nanoscale technologies whose future could strongly depend on the implementation of FIB in the role of a nanoscale fabrication tool for rapid prototyping. Among the other described technologies are 'ballistic' magnetoresistance, patterned magnetic media, magnetoresistive RAM (MRAM), and magnetic force microscopy.

  17. A novel technique for presurgical nasoalveolar molding using computer-aided reverse engineering and rapid prototyping.

    Science.gov (United States)

    Yu, Quan; Gong, Xin; Wang, Guo-Min; Yu, Zhe-Yuan; Qian, Yu-Fen; Shen, Gang

    2011-01-01

    To establish a new method of presurgical nasoalveolar molding (NAM) using computer-aided reverse engineering and rapid prototyping technique in infants with unilateral cleft lip and palate (UCLP). Five infants (2 males and 3 females with mean age of 1.2 w) with complete UCLP were recruited. All patients were subjected to NAM before the cleft lip repair. The upper denture casts were recorded using a three-dimensional laser scanner within 2 weeks after birth in UCLP infants. A digital model was constructed and analyzed to simulate the NAM procedure with reverse engineering software. The digital geometrical data were exported to print the solid model with rapid prototyping system. The whole set of appliances was fabricated based on these solid models. Laser scanning and digital model construction simplified the NAM procedure and estimated the treatment objective. The appliances were fabricated based on the rapid prototyping technique, and for each patient, the complete set of appliances could be obtained at one time. By the end of presurgical NAM treatment, the cleft was narrowed, and the malformation of nasoalveolar segments was aligned normally. We have developed a novel technique of presurgical NAM based on a computer-aided design. The accurate digital denture model of UCLP infants could be obtained with laser scanning. The treatment design and appliance fabrication could be simplified with a computer-aided reverse engineering and rapid prototyping technique.

  18. Rapid Prototyping Technologies and their Applications in Prosthodontics, a Review of Literature.

    Science.gov (United States)

    Torabi, Kianoosh; Farjood, Ehsan; Hamedani, Shahram

    2015-03-01

    The early computer-aided design/computer-aided manufacturing (CAD/CAM) systems were relied exclusively on subtractive methods. In recent years, additive methods by employing rapid prototyping (RP) have progressed rapidly in various fields of dentistry as they have the potential to overcome known drawbacks of subtractive techniques such as fit problems. RP techniques have been exploited to build complex 3D models in medicine since the 1990s. RP has recently proposed successful applications in various dental fields, such as fabrication of implant surgical guides, frameworks for fixed and removable partial dentures, wax patterns for the dental prosthesis, zirconia prosthesis and molds for metal castings, and maxillofacial prosthesis and finally, complete dentures. This paper aimed to offer a comprehensive literature review of various RP methods, particularly in dentistry, that are expected to bring many improvements to the field. A search was made through MEDLINE database and Google scholar search engine. The keywords; 'rapid prototyping' and 'dentistry' were searched in title/abstract of publications; limited to 2003 to 2013, concerning past decade. The inclusion criterion was the technical researches that predominately included laboratory procedures. The exclusion criterion was meticulous clinical and excessive technical procedures. A total of 106 articles were retrieved, recited by authors and only 50 met the specified inclusion criteria for this review. Selected articles had used rapid prototyping techniques in various fields in dentistry through different techniques. This review depicted the different laboratory procedures employed in this method and confirmed that RP technique have been substantially feasible in dentistry. With advancement in various RP systems, it is possible to benefit from this technique in different dental practices, particularly in implementing dental prostheses for different applications.

  19. Rapid Prototyping Amphiphilic Polymer/Hydroxyapatite Composite Scaffolds with Hydration-Induced Self-Fixation Behavior

    Science.gov (United States)

    Kutikov, Artem B.; Gurijala, Anvesh

    2015-01-01

    Two major factors hampering the broad use of rapid prototyped biomaterials for tissue engineering applications are the requirement for custom-designed or expensive research-grade three-dimensional (3D) printers and the limited selection of suitable thermoplastic biomaterials exhibiting physical characteristics desired for facile surgical handling and biological properties encouraging tissue integration. Properly designed thermoplastic biodegradable amphiphilic polymers can exhibit hydration-dependent hydrophilicity changes and stiffening behavior, which may be exploited to facilitate the surgical delivery/self-fixation of the scaffold within a physiological tissue environment. Compared to conventional hydrophobic polyesters, they also present significant advantages in blending with hydrophilic osteoconductive minerals with improved interfacial adhesion for bone tissue engineering applications. Here, we demonstrated the excellent blending of biodegradable, amphiphilic poly(D,L-lactic acid)-poly(ethylene glycol)-poly(D,L-lactic acid) (PLA-PEG-PLA) (PELA) triblock co-polymer with hydroxyapatite (HA) and the fabrication of high-quality rapid prototyped 3D macroporous composite scaffolds using an unmodified consumer-grade 3D printer. The rapid prototyped HA-PELA composite scaffolds and the PELA control (without HA) swelled (66% and 44% volume increases, respectively) and stiffened (1.38-fold and 4-fold increases in compressive modulus, respectively) in water. To test the hypothesis that the hydration-induced physical changes can translate into self-fixation properties of the scaffolds within a confined defect, a straightforward in vitro pull-out test was designed to quantify the peak force required to dislodge these scaffolds from a simulated cylindrical defect at dry versus wet states. Consistent with our hypothesis, the peak fixation force measured for the PELA and HA-PELA scaffolds increased 6-fold and 15-fold upon hydration, respectively. Furthermore, we showed that

  20. Modeling of welded bead profile for rapid prototyping by robotic MAG welding

    Institute of Scientific and Technical Information of China (English)

    CAO Yong; ZHU Sheng; WANG Tao; WANG Wanglong

    2009-01-01

    As a deposition technology, robotic metal active gas(MAG) welding has shown new promise for rapid prototyping (RP) of metallic parts. During the process of metal forming using robotic MAG welding, sectional profile of single-pass welded bead is critical to formed accuracy and quality of metal pans. In this paper, the experiments of single-pass welded bead for rapid prototyping using robotic MAG welding were carried out. The effect of some edge detectors on the cross-sectional edge of welded bead was discussed and curve fitting was applied using leat square fitting. Consequently, the mathematical model of welded bead profile was developed. The experimental results show that good shape could be obtained under suitable welding parameters. Canny operawr is suitable to edge detection of welded bead profile, and the mathematical model of welded bead profile developed is approximately parabola.

  1. A Practical Approach to Rapid Prototyping of SCA Waveforms

    OpenAIRE

    DePriest, Jacob Andrew

    2006-01-01

    With the growing interest in software defined radios (SDRs), cognitive radios, the Joint Tactical Radio System (JTRS), and the Software Communication Architecture (SCA) comes the need for a rapid prototyping approach to radio design. In the past, radios have traditionally been designed to have a static implementation with the express goal of implementing a specific type of communication, such as 802.11b, CDMA voice communication, or just a simple FM tuner. However, when designing an ...

  2. [Osteogenic activity of porous calcium phosphate ceramics fabricated by rapid prototyping].

    Science.gov (United States)

    He, Chenguang; Zhao, Li; Lin, Liulan; Gu, Huijie; Zhou, Heng; Cui, Lei

    2010-07-01

    Calcium phosphate bioceramics has a broad application prospect because of good biocompatibility, but porous scaffolds with complex shape can not be prepared by the traditional methods. To fabricate porous calcium phosphate ceramics by rapid prototyping and to investigate the in vitro osteogenic activities. The porous calcium phosphate ceramics was fabricated by rapid prototyping. The bone marrow mesenchymal stem cells (BMSCs) were isolated from bone marrow of Beagle canine, and the 3rd passage BMSCs were seeded onto the porous ceramics. The cell/ceramics composite cultured in osteogenic medium were taken as the experimental group (group A) and the cell/ceramics composite cultured in growth medium were taken as the control group (group B). Meanwhile, the cells seeded on the culture plate were cultured in osteogenic medium or growth medium respectively as positive control (group C) or negative control (group D). After 1, 3, and 7 days of culture, the cell proliferation and osteogenic differentiation on the porous ceramics were evaluated by DNA quantitative analysis, histochemical staining and alkaline phosphatase (ALP) activity. After DiO fluorescent dye, the cell adhesion, growth, and proliferation on the porous ceramics were also observed by confocal laser scanning microscope (CLSM). DNA quantitative analysis results showed that the number of BMSCs in all groups increased continuously with time. Plateau phase was not obvious in groups A and B, but it was clearly observed in groups C and D. The CLSM observation indicated that the activity of BMSCs was good and the cells spread extensively, showing good adhesion and proliferation on the porous calcium phosphate ceramics prepared by rapid prototyping. ALP quantitative analysis results showed that the stain of cells on the ceramics became deeper and deeper with time in groups A and B, the staining degree in group A were stronger than that in group B. There was no significant difference in the change of the ALP activity

  3. New Strategies for Powder Compaction in Powder-based Rapid Prototyping Techniques

    NARCIS (Netherlands)

    Budding, A.; Vaneker, Thomas H.J.

    2013-01-01

    In powder-based rapid prototyping techniques, powder compaction is used to create thin layers of fine powder that are locally bonded. By stacking these layers of locally bonded material, an object is made. The compaction of thin layers of powder mater ials is of interest for a wide range of

  4. Rapid prototyping of centrifugal microfluidic modules for point of care blood testing

    CSIR Research Space (South Africa)

    Madzivhandila, Phophi

    2016-11-01

    Full Text Available We present modular centrifugal microfluidic devices that enable a series of blood tests to be performed towards a full blood count. The modular approach allows for rapid prototyping of device components in a generic format to complete different...

  5. Performance of a Micro-UAV lifting system built with the usage of rapid prototyping methods

    International Nuclear Information System (INIS)

    Dalewski, R T; Gumowski, K; Barczak, T; Godek, J

    2014-01-01

    This article presents results of the aerodynamic testing of a micro unmanned aerial vehicle rotor efficiency. The rotors were prepared as a set of two rotors in a counter-rotating ducted drive. Prototypes of the drives were made using two rapid prototyping techniques – FDM – fused deposition modelling method and SLS – selective laser sintering. Rotors were made then treated by introducing additional finishing cyanoacrylate coating and abrasive processing. Main differences between those models were observed in fan shape, porosity, surface roughness and mechanical properties – stiffness. An influence of these factors was observed on an aerodynamic efficiency. For the obtained prototypes both simulations and experimental testing were conducted with thrust, power, torque measurements, as well as the measurement of velocity and pressure distribution at the outlet of the duct. The results show the possibility of using rapid prototyping techniques to produce prototypes of drives operating in the low and medium Reynolds numbers (6000-60000), and the aerodynamic shape relevant factors affecting the preparation and performance of such drives. In addition, simulation studies were performed using the Fluent environment where experimental results were confronted with the results of simulation studies.

  6. Uranus: a rapid prototyping tool for FPGA embedded computer vision

    Science.gov (United States)

    Rosales-Hernández, Victor; Castillo-Jimenez, Liz; Viveros-Velez, Gilberto; Zuñiga-Grajeda, Virgilio; Treviño Torres, Abel; Arias-Estrada, M.

    2007-01-01

    The starting point for all successful system development is the simulation. Performing high level simulation of a system can help to identify, insolate and fix design problems. This work presents Uranus, a software tool for simulation and evaluation of image processing algorithms with support to migrate them to an FPGA environment for algorithm acceleration and embedded processes purposes. The tool includes an integrated library of previous coded operators in software and provides the necessary support to read and display image sequences as well as video files. The user can use the previous compiled soft-operators in a high level process chain, and code his own operators. Additional to the prototyping tool, Uranus offers FPGA-based hardware architecture with the same organization as the software prototyping part. The hardware architecture contains a library of FPGA IP cores for image processing that are connected with a PowerPC based system. The Uranus environment is intended for rapid prototyping of machine vision and the migration to FPGA accelerator platform, and it is distributed for academic purposes.

  7. Rapid Prototyping of Nanofluidic Slits in a Silicone Bilayer

    Science.gov (United States)

    Kole, Thomas P.; Liao, Kuo-Tang; Schiffels, Daniel; Ilic, B. Robert; Strychalski, Elizabeth A.; Kralj, Jason G.; Liddle, J. Alexander; Dritschilo, Anatoly; Stavis, Samuel M.

    2015-01-01

    This article reports a process for rapidly prototyping nanofluidic devices, particularly those comprising slits with microscale widths and nanoscale depths, in silicone. This process consists of designing a nanofluidic device, fabricating a photomask, fabricating a device mold in epoxy photoresist, molding a device in silicone, cutting and punching a molded silicone device, bonding a silicone device to a glass substrate, and filling the device with aqueous solution. By using a bilayer of hard and soft silicone, we have formed and filled nanofluidic slits with depths of less than 400 nm and aspect ratios of width to depth exceeding 250 without collapse of the slits. An important attribute of this article is that the description of this rapid prototyping process is very comprehensive, presenting context and details which are highly relevant to the rational implementation and reliable repetition of the process. Moreover, this process makes use of equipment commonly found in nanofabrication facilities and research laboratories, facilitating the broad adaptation and application of the process. Therefore, while this article specifically informs users of the Center for Nanoscale Science and Technology (CNST) at the National Institute of Standards and Technology (NIST), we anticipate that this information will be generally useful for the nanofabrication and nanofluidics research communities at large, and particularly useful for neophyte nanofabricators and nanofluidicists. PMID:26958449

  8. Studying the Technology of Creating Cortical Electrode Instruments using the Rapid Prototyping Technology

    Directory of Open Access Journals (Sweden)

    Ablyaz T. R.

    2017-06-01

    Full Text Available This paper shows the results of studying the technology of manufacturing cortical electrode-instruments (EI with the use of indirect methods of the Rapid Prototyping technology. Functional EI prototypes were made by layered synthesis of the photopolymer material with the use of the stereolithography technology (SLA - Stereo Lithography Apparatus. The article is focused on two methods of indirect EI manufacturing. One of the EI prototypes was used for making a molded wax model for hot investment casting, followed by applying copper coating. The second prototype was used for applying copper plating to a prepared current-conductive layer. As a result of EDMing a steel workpiece, both EIs reached the desired depth, which is 1 mm. The copper plating applied to the EI preserves its integrity. Through the use of the casting technology, there is a possibility to cut the economic costs by 35%. Using a prototype with preliminarily applied conductive coating makes it possible to make geometrically-complex EIs.

  9. Comparative study of manufacturing condyle implant using rapid prototyping and CNC machining

    Science.gov (United States)

    Bojanampati, S.; Karthikeyan, R.; Islam, MD; Venugopal, S.

    2018-04-01

    Injuries to the cranio-maxillofacial area caused by road traffic accidents (RTAs), fall from heights, birth defects, metabolic disorders and tumors affect a rising number of patients in the United Arab Emirates (UAE), and require maxillofacial surgery. Mandibular reconstruction poses a specific challenge in both functionality and aesthetics, and involves replacement of the damaged bone by a custom made implant. Due to material, design cycle time and manufacturing process time, such implants are in many instances not affordable to patients. In this paper, the feasibility of designing and manufacturing low-cost, custom made condyle implant is assessed using two different approaches, consisting of rapid prototyping and three-axis computer numerically controlled (CNC) machining. Two candidate rapid prototyping techniques are considered, namely fused deposition modeling (FDM) and three-dimensional printing followed by sand casting The feasibility of the proposed manufacturing processes is evaluated based on manufacturing time, cost, quality, and reliability.

  10. Integration of image guidance and rapid prototyping technology in craniofacial surgery.

    Science.gov (United States)

    Bullock, P; Dunaway, D; McGurk, L; Richards, R

    2013-08-01

    This technical note demonstrates the benefits of preoperative planning, involving the use of rapid prototype models and rehearsal of the surgical procedure, using image-guided navigational surgery. Optimum reconstruction of large defects can be achieved with this technique. Copyright © 2013 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  11. A pilot biomedical engineering course in rapid prototyping for mobile health.

    Science.gov (United States)

    Stokes, Todd H; Venugopalan, Janani; Hubbard, Elena N; Wang, May D

    2013-01-01

    Rapid prototyping of medically assistive mobile devices promises to fuel innovation and provides opportunity for hands-on engineering training in biomedical engineering curricula. This paper presents the design and outcomes of a course offered during a 16-week semester in Fall 2011 with 11 students enrolled. The syllabus covered a mobile health design process from end-to-end, including storyboarding, non-functional prototypes, integrated circuit programming, 3D modeling, 3D printing, cloud computing database programming, and developing patient engagement through animated videos describing the benefits of a new device. Most technologies presented in this class are open source and thus provide unlimited "hackability". They are also cost-effective and easily transferrable to other departments.

  12. Rapid Prototyping of an Electrically-Small Antenna for Binaural-Hearing Instruments

    DEFF Research Database (Denmark)

    Ruaro, Andrea; Thaysen, Jesper; Jakobsen, Kaj Bjarne

    2015-01-01

    Rapid prototyping is emerging as a technology that can provide detailed mechanical parts, e.g., for use in antenna mock-ups, in a short lead time. Nevertheless, one of the main issues associated with it is that the materials suitable for 3D printing are not characterized at radio frequencies (RF......). This study analyzes the main RF parameters (dielectric constant, loss tangent, surface roughness) and applies the results to the modeling of the prototype of an electrically small (ESA) antenna for binaural hearing instruments applications. After discussing the specific technology choices...... and their relevancies, it is shown how the analyzed parameters can be used to obtain good correlation between simulations and measurements....

  13. Rapid prototyping of an EEG-based brain-computer interface (BCI).

    Science.gov (United States)

    Guger, C; Schlögl, A; Neuper, C; Walterspacher, D; Strein, T; Pfurtscheller, G

    2001-03-01

    The electroencephalogram (EEG) is modified by motor imagery and can be used by patients with severe motor impairments (e.g., late stage of amyotrophic lateral sclerosis) to communicate with their environment. Such a direct connection between the brain and the computer is known as an EEG-based brain-computer interface (BCI). This paper describes a new type of BCI system that uses rapid prototyping to enable a fast transition of various types of parameter estimation and classification algorithms to real-time implementation and testing. Rapid prototyping is possible by using Matlab, Simulink, and the Real-Time Workshop. It is shown how to automate real-time experiments and perform the interplay between on-line experiments and offline analysis. The system is able to process multiple EEG channels on-line and operates under Windows 95 in real-time on a standard PC without an additional digital signal processor (DSP) board. The BCI can be controlled over the Internet, LAN or modem. This BCI was tested on 3 subjects whose task it was to imagine either left or right hand movement. A classification accuracy between 70% and 95% could be achieved with two EEG channels after some sessions with feedback using an adaptive autoregressive (AAR) model and linear discriminant analysis (LDA).

  14. Design of rapid prototype of UAV line-of-sight stabilized control system

    Science.gov (United States)

    Huang, Gang; Zhao, Liting; Li, Yinlong; Yu, Fei; Lin, Zhe

    2018-01-01

    The line-of-sight (LOS) stable platform is the most important technology of UAV (unmanned aerial vehicle), which can reduce the effect to imaging quality from vibration and maneuvering of the aircraft. According to the requirement of LOS stability system (inertial and optical-mechanical combined method) and UAV's structure, a rapid prototype is designed using based on industrial computer using Peripheral Component Interconnect (PCI) and Windows RTX to exchange information. The paper shows the control structure, and circuit system including the inertial stability control circuit with gyro and voice coil motor driven circuit, the optical-mechanical stability control circuit with fast-steering-mirror (FSM) driven circuit and image-deviation-obtained system, outer frame rotary follower, and information-exchange system on PC. Test results show the stability accuracy reaches 5μrad, and prove the effectiveness of the combined line-of-sight stabilization control system, and the real-time rapid prototype runs stable.

  15. Parametric Design and Rapid Prototyping of Installation Box for Vehicle Terminal PCB

    Directory of Open Access Journals (Sweden)

    Wang Xingxing

    2016-01-01

    Full Text Available Installation box for vehicle terminal PCB (Printed Circuit Board was took as research object, which is encountered in the process of project developing. Vehicle terminal PCB in actual development process was set as an example, point cloud data were acquired by three coordinate measuring method; Imageware software was used to reconstruct the vehicle terminal PCB model, basic size parameters of vehicle terminal PCB can be got and then design parameters of installation box for vehicle terminal PCB can be determined. Design of the installation box for vehicle terminal PCB was completed based on Solidworks software, then 3D modeling and 2D drawing of installation box for vehicle terminal PCB was gained. Up Plus 2 rapid prototype machine was used to manufacture installation box for vehicle terminal PCB rapidly based on 3D printing technology, then prototype of installation box for vehicle terminal PCB was obtained. It is of certain engineering significant for single (small amount manufacturing of installation box for general PCB.

  16. Using three-dimensional rapid prototyping in the design and development of orthopaedic screws in standardised pull-out tests.

    Science.gov (United States)

    Leslie, Laura Jane; Connolly, Ashley; Swadener, John G; Junaid, Sarah; Theivendran, Kanthan; Deshmukh, Subodh C

    2018-05-01

    The majority of orthopaedic screws are designed, tested and manufactured by existing orthopaedics companies and are predominantly developed with healthy bone in mind. The timescales and costs involved in the development of a new screw design, for example, for osteoporotic bone, are high. In this study, standard wood screws were used to analyse the concept of using three-dimensional printing, or rapid prototyping, as a viable stage of development in the design of a new bone screw. Six wood screws were reverse engineered and printed in polymeric material using stereolithography. Three of the designs were also printed in Ti6Al4V using direct metal laser sintering; however, these were not of sufficient quality to test further. Both the original metal screws (metal) and polymeric rapid prototyping screws were then tested using standard pull-out tests from low-density polyurethane blocks (Sawbones). Results showed the highest pull-out strengths for screws with the longest thread length and the smallest inner diameter. Of the six screw designs tested, five showed no more than a 17% variance between the metal and rapid prototyping results. A similar pattern of results was shown between the screw designs for both the metal and rapid prototyping screws in five of the six cases. While not producing fully comparable pull-out results to orthopaedic screws, the results from this study do provide evidence of the potential usefulness and cost-effectiveness of rapid prototyping in the early stages of design and testing of orthopaedic screws.

  17. Rapid Prototyping of Formally Modelled Distributed Systems

    OpenAIRE

    Buchs, Didier; Buffo, Mathieu; Titsworth, Frances M.

    1999-01-01

    This paper presents various kinds of prototypes, used in the prototyping of formally modelled distributed systems. It presents the notions of prototyping techniques and prototype evolution, and shows how to relate them to the software life-cycle. It is illustrated through the use of the formal modelling language for distributed systems CO-OPN/2.

  18. Rapid Prototyping of High Performance Signal Processing Applications

    Science.gov (United States)

    Sane, Nimish

    Advances in embedded systems for digital signal processing (DSP) are enabling many scientific projects and commercial applications. At the same time, these applications are key to driving advances in many important kinds of computing platforms. In this region of high performance DSP, rapid prototyping is critical for faster time-to-market (e.g., in the wireless communications industry) or time-to-science (e.g., in radio astronomy). DSP system architectures have evolved from being based on application specific integrated circuits (ASICs) to incorporate reconfigurable off-the-shelf field programmable gate arrays (FPGAs), the latest multiprocessors such as graphics processing units (GPUs), or heterogeneous combinations of such devices. We, thus, have a vast design space to explore based on performance trade-offs, and expanded by the multitude of possibilities for target platforms. In order to allow systematic design space exploration, and develop scalable and portable prototypes, model based design tools are increasingly used in design and implementation of embedded systems. These tools allow scalable high-level representations, model based semantics for analysis and optimization, and portable implementations that can be verified at higher levels of abstractions and targeted toward multiple platforms for implementation. The designer can experiment using such tools at an early stage in the design cycle, and employ the latest hardware at later stages. In this thesis, we have focused on dataflow-based approaches for rapid DSP system prototyping. This thesis contributes to various aspects of dataflow-based design flows and tools as follows: 1. We have introduced the concept of topological patterns, which exploits commonly found repetitive patterns in DSP algorithms to allow scalable, concise, and parameterizable representations of large scale dataflow graphs in high-level languages. We have shown how an underlying design tool can systematically exploit a high

  19. Rapid prototyping of nanotube-based devices using topology-optimized microgrippers

    DEFF Research Database (Denmark)

    Sardan, Özlem; Eichhorn, Volkmar; Petersen, D.H.

    2008-01-01

    Nanorobotic handling of carbon nanotubes (CNTs) using microgrippers is one of the most promising approaches for the rapid characterization of the CNTs and also for the assembly of prototypic nanotube-based devices. In this paper, we present pick-and-place nanomanipulation of multi-walled CNTs...... in a rapid and a reproducible manner. We placed CNTs on copper TEM grids for structural analysis and on AFM probes for the assembly of AFM super-tips. We used electrothermally actuated polysilicon microgrippers designed using topology optimization in the experiments. The microgrippers are able to open...... with an amorphous carbon layer, which is locally removed at the contact points with the microgripper. The assembled AFM super-tips are used for AFM measurements of microstructures with high aspect ratios....

  20. [Reliability of three dimensional resin model by rapid prototyping manufacturing and digital modeling].

    Science.gov (United States)

    Zeng, Fei-huang; Xu, Yuan-zhi; Fang, Li; Tang, Xiao-shan

    2012-02-01

    To describe a new technique for fabricating an 3D resin model by 3D reconstruction and rapid prototyping, and to analyze the precision of this method. An optical grating scanner was used to acquire the data of silastic cavity block , digital dental cast was reconstructed with the data through Geomagic Studio image processing software. The final 3D reconstruction was saved in the pattern of Stl. The 3D resin model was fabricated by fuse deposition modeling, and was compared with the digital model and gypsum model. The data of three groups were statistically analyzed using SPSS 16.0 software package. No significant difference was found in gypsum model,digital dental cast and 3D resin model (P>0.05). Rapid prototyping manufacturing and digital modeling would be helpful for dental information acquisition, treatment design, appliance manufacturing, and can improve the communications between patients and doctors.

  1. Software for rapid prototyping in the pharmaceutical and biotechnology industries.

    Science.gov (United States)

    Kappler, Michael A

    2008-05-01

    The automation of drug discovery methods continues to develop, especially techniques that process information, represent workflow and facilitate decision-making. The magnitude of data and the plethora of questions in pharmaceutical and biotechnology research give rise to the need for rapid prototyping software. This review describes the advantages and disadvantages of three solutions: Competitive Workflow, Taverna and Pipeline Pilot. Each of these systems processes large amounts of data, integrates diverse systems and assists novice programmers and human experts in critical decision-making steps.

  2. Rapid prototyping of the Central Safety System for Nuclear Risk in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Scibile, L. [ITER Organization, CS 90 046, St. Paul-lez-Durance, Cedex (France); Ambrosino, G. [Consorzio CREATE, Universita degli Studi di Napoli Federico II, via Claudio 21, 80125, Napoli (Italy); De Tommasi, G., E-mail: detommas@unina.i [Consorzio CREATE, Universita degli Studi di Napoli Federico II, via Claudio 21, 80125, Napoli (Italy); Pironti, A. [Consorzio CREATE, Universita degli Studi di Napoli Federico II, via Claudio 21, 80125, Napoli (Italy)

    2010-07-15

    The Central Safety System for Nuclear Risk (CSS-N) coordinates the safety control systems to ensure nuclear safety for the ITER complex. Since the CSS-N is a safety critical system, its validation and commissioning play a very important role; in particular the required level of reliability must be demonstrated. In such a scenario, it is strongly recommended to use modeling and simulation tools since the early design phase. Indeed, the modeling tools will help in the definition of the control system requirements. Furthermore the models can than be used for the rapid prototyping of the safety system. Hardware-in-the-loop simulations can also be performed in order to assess the performance of the control hardware against a plant simulator. The proposed approach relies on the availability of a plant simulator to develop the prototype of the control system. This paper introduces the methodology used to design and develop both the CSS-N Oriented Plant Simulator and the CSS-N Prototype.

  3. Rapid prototyping of the Central Safety System for Nuclear Risk in ITER

    International Nuclear Information System (INIS)

    Scibile, L.; Ambrosino, G.; De Tommasi, G.; Pironti, A.

    2010-01-01

    The Central Safety System for Nuclear Risk (CSS-N) coordinates the safety control systems to ensure nuclear safety for the ITER complex. Since the CSS-N is a safety critical system, its validation and commissioning play a very important role; in particular the required level of reliability must be demonstrated. In such a scenario, it is strongly recommended to use modeling and simulation tools since the early design phase. Indeed, the modeling tools will help in the definition of the control system requirements. Furthermore the models can than be used for the rapid prototyping of the safety system. Hardware-in-the-loop simulations can also be performed in order to assess the performance of the control hardware against a plant simulator. The proposed approach relies on the availability of a plant simulator to develop the prototype of the control system. This paper introduces the methodology used to design and develop both the CSS-N Oriented Plant Simulator and the CSS-N Prototype.

  4. A high performance, high precision, low cost rapid prototyping and manufacturing technology

    OpenAIRE

    Viacheslav R. Shulunov

    2014-01-01

    A novel roll powder sintering (RPS) technology is proposed for processing real plastic, ceramic, metal and other 3-D objects 1m³ (or more) in volume directly from a CAD model within several hours. The breakthrough advantages of the technology are compared to the dominant rapid prototyping and manufacturing (RP&M) processes that are currently on the market.

  5. CAD – CAM PROCEDURE USING FOR RAPID PROTOTYPING WITH APPLICATION IN BIOMECHANICS

    Directory of Open Access Journals (Sweden)

    BRAUN Barbu

    2015-06-01

    Full Text Available The paper presents a new and efficient method for modeling some components with application in Biomechanics. It is shown the way in which this method could be successfully applied for orthopedic shoes, namely for foot insoles to correct any plantar deformities. The main advantages of the proposed method refer to low costs, successfully applying for different products for Biomechanics. The prototyped models via CAD/CAM method allowed a rapid and efficient improvement of their design. Another advantage refer to the fact that these can be properly and efficiently tested before prototyping by the point of view of mechanical stress, due to prior simulations, eliminating all costs meaning wastes or adjustments.

  6. Automated Test Case Generation for an Autopilot Requirement Prototype

    Science.gov (United States)

    Giannakopoulou, Dimitra; Rungta, Neha; Feary, Michael

    2011-01-01

    Designing safety-critical automation with robust human interaction is a difficult task that is susceptible to a number of known Human-Automation Interaction (HAI) vulnerabilities. It is therefore essential to develop automated tools that provide support both in the design and rapid evaluation of such automation. The Automation Design and Evaluation Prototyping Toolset (ADEPT) enables the rapid development of an executable specification for automation behavior and user interaction. ADEPT supports a number of analysis capabilities, thus enabling the detection of HAI vulnerabilities early in the design process, when modifications are less costly. In this paper, we advocate the introduction of a new capability to model-based prototyping tools such as ADEPT. The new capability is based on symbolic execution that allows us to automatically generate quality test suites based on the system design. Symbolic execution is used to generate both user input and test oracles user input drives the testing of the system implementation, and test oracles ensure that the system behaves as designed. We present early results in the context of a component in the Autopilot system modeled in ADEPT, and discuss the challenges of test case generation in the HAI domain.

  7. Rapid prototyping prosthetic hand acting by a low-cost shape-memory-alloy actuator.

    Science.gov (United States)

    Soriano-Heras, Enrique; Blaya-Haro, Fernando; Molino, Carlos; de Agustín Del Burgo, José María

    2018-06-01

    The purpose of this article is to develop a new concept of modular and operative prosthetic hand based on rapid prototyping and a novel shape-memory-alloy (SMA) actuator, thus minimizing the manufacturing costs. An underactuated mechanism was needed for the design of the prosthesis to use only one input source. Taking into account the state of the art, an underactuated mechanism prosthetic hand was chosen so as to implement the modifications required for including the external SMA actuator. A modular design of a new prosthesis was developed which incorporated a novel SMA actuator for the index finger movement. The primary objective of the prosthesis is achieved, obtaining a modular and functional low-cost prosthesis based on additive manufacturing executed by a novel SMA actuator. The external SMA actuator provides a modular system which allows implementing it in different systems. This paper combines rapid prototyping and a novel SMA actuator to develop a new concept of modular and operative low-cost prosthetic hand.

  8. EasyInterface: A toolkit for rapid development of GUIs for research prototype tools

    OpenAIRE

    Doménech, Jesús; Genaim, Samir; Johnsen, Einar Broch; Schlatte, Rudolf

    2017-01-01

    In this paper we describe EasyInterface, an open-source toolkit for rapid development of web-based graphical user interfaces (GUIs). This toolkit addresses the need of researchers to make their research prototype tools available to the community, and integrating them in a common environment, rapidly and without being familiar with web programming or GUI libraries in general. If a tool can be executed from a command-line and its output goes to the standard output, then in few minutes one can m...

  9. PENGARUH POSISI ORIENTASI OBJEK PADA PROSES RAPID PROTOTYPING 3D PRINTING TERHADAP KEKUATAN TARIK MATERIAL POLYMER

    Directory of Open Access Journals (Sweden)

    Lubis Sobron

    2016-12-01

    Full Text Available Pembuatan prototipe pada industri manufaktur berkembang dengan pesat, berawal dari pembuatan secara konvensional, kemudian dilakukan dengan menggunakan mesin-mesin perkakas, dan berkembang dengan pemanfaatan komputer sebagai alat kontrol pada mesin tersebut sehingga dikenal dengan istilah CNC (computer numerically control. Pada awalnya, pembuatan prototipe dilakukan menggunakan mesin perkakas yang membentuk kontur permukaan dengan melakukan pemotongan pada  benda kerja, tentunya dalam hal ini terdapat bahan tersisa yang dikenal dengan chip. Dewasa ini perkembangan dalam pembuatan prototipe maju dengan pesat yang dikenal dengan pembuatan prototipe cepat (rapid prorotyping. Keunggulan dari rapid prototyping dalam bidang manufaktur adalah kemudahannya dalam menghasilkan suatu produk yang kompleks dengan tepat dan efisien. Proses rapid prototyping mampu merealisasikan hasil permodelan 3D software dalam bentuk nyata tanpa intervensi apapun. Dalam penelitian ini, dikaji tentang pengaruh penentuan posisi orientasi secara vertical dan horizontal terhadap kekuatan Tarik material polymer yang digunakan. Penelitian dilakukan dengan dengan menggunakan perangkat rapid prototyping tipe fused deposition modeling yakni 3D printing. Bahan filament yang digunakan jenis polymer PLA dan ABS. Proses printing dilakukan terhadap bentuk objek uji Tarik ASTM D638. Proses 3D printing dilakukan dengan memvariasikan posisi orientasi objek secara vertikal dan horizontal. Spesimen yang dihasilkan selanjutnya dilakukan uji tarik. Berdasarkan hasil pengujian yang dilakukan dapat diketahui bahwa penentuan orientasi posisi objek spesimen memberi pengaruh terhadap tegangan tarik spesimen.

  10. Development Of A Data Assimilation Capability For RAPID

    Science.gov (United States)

    Emery, C. M.; David, C. H.; Turmon, M.; Hobbs, J.; Allen, G. H.; Famiglietti, J. S.

    2017-12-01

    The global decline of in situ observations associated with the increasing ability to monitor surface water from space motivates the creation of data assimilation algorithms that merge computer models and space-based observations to produce consistent estimates of terrestrial hydrology that fill the spatiotemporal gaps in observations. RAPID is a routing model based on the Muskingum method that is capable of estimating river streamflow over large scales with a relatively short computing time. This model only requires limited inputs: a reach-based river network, and lateral surface and subsurface flow into the rivers. The relatively simple model physics imply that RAPID simulations could be significantly improved by including a data assimilation capability. Here we present the early developments of such data assimilation approach into RAPID. Given the linear and matrix-based structure of the model, we chose to apply a direct Kalman filter, hence allowing for the preservation of high computational speed. We correct the simulated streamflows by assimilating streamflow observations and our early results demonstrate the feasibility of the approach. Additionally, the use of in situ gauges at continental scales motivates the application of our new data assimilation scheme to altimetry measurements from existing (e.g. EnviSat, Jason 2) and upcoming satellite missions (e.g. SWOT), and ultimately apply the scheme globally.

  11. GIS/RS-based Rapid Reassessment for Slope Land Capability Classification

    Science.gov (United States)

    Chang, T. Y.; Chompuchan, C.

    2014-12-01

    Farmland resources in Taiwan are limited because about 73% is mountainous and slope land. Moreover, the rapid urbanization and dense population resulted in the highly developed flat area. Therefore, the utilization of slope land for agriculture is more needed. In 1976, "Slope Land Conservation and Utilization Act" was promulgated to regulate the slope land utilization. Consequently, slope land capability was categorized into Class I-IV according to 4 criteria, i.e., average land slope, effective soil depth, degree of soil erosion, and parent rock. The slope land capability Class I-VI are suitable for cultivation and pasture. Whereas, Class V should be used for forestry purpose and Class VI should be the conservation land which requires intensive conservation practices. The field survey was conducted to categorize each land unit as the classification scheme. The landowners may not allow to overuse land capability limitation. In the last decade, typhoons and landslides frequently devastated in Taiwan. The rapid post-disaster reassessment of the slope land capability classification is necessary. However, the large-scale disaster on slope land is the constraint of field investigation. This study focused on using satellite remote sensing and GIS as the rapid re-evaluation method. Chenyulan watershed in Nantou County, Taiwan was selected to be a case study area. Grid-based slope derivation, topographic wetness index (TWI) and USLE soil loss calculation were used to classify slope land capability. The results showed that GIS-based classification give an overall accuracy of 68.32%. In addition, the post-disaster areas of Typhoon Morakot in 2009, which interpreted by SPOT satellite imageries, were suggested to classify as the conservation lands. These tools perform better in the large coverage post-disaster update for slope land capability classification and reduce time-consuming, manpower and material resources to the field investigation.

  12. Development of a prototype for dissolved CO2 rapid measurement and preliminary tests

    Science.gov (United States)

    Li, Meng; Guo, Jinjia; Zhang, Zhihao; Luo, Zhao; Qin, Chuan; Zheng, Ronger

    2017-10-01

    The measurements of dissolved CO2 in seawater is of great significance for the study of global carbon cycle. At present, the commercial sensors used for dissolved CO2 measurements are mostly equipped with permeable membranes for the purpose of gas-liquid separation, with the advantages of easy operation, low cost, etc.. However, most of these devices measure CO2 after reaching gas equilibrium, so it takes a few minutes to respond, which limited its applications in rapid measurements. In this paper, a set of prototype was developed for the rapid measurements of dissolved CO2. The system was built basing the direct absorption TDLAS. To detect the CO2 absorption line located at 4991.26 cm-1 , a fiber-coupled DFB laser operating at 2004 nm was selected as the light source. A Herriott type multi-pass cavity with an effective optical path length of 10 m and an inner volume of 90 mL was used for absorption measurements. A detection limit of 26 μatm can be obtained with this compact cavity. To realize the rapid measurements of dissolved CO2, a degasser with high degassing rate was necessary. A hollow fiber membrane with a large permeable area used in this paper can achieve degassing rate up to 2.88 kPa/min. Benefitted from the high degassing rate of the degasser and high sensitivity of the compact TDLAS system, a rapid measurement of dissolved CO2 in water can be achieved within 1s time, and the response time of the prototype when the dissolved CO2 concentration changed abruptly in actual measurement was 15 s. To evaluate the performance of the prototype, comparison measurements were carried out with a commercial mass spectrometer. The dissolved CO2 in both seawater and tap-water was measured, and the experimental results showed good consistent trends with R2 of 0.973 and 0.931. The experimental results proved the feasibility of dissolved CO2 rapid measurement. In the near future, more system evaluation experiments will be carried out and the system will be further

  13. TOPAZ II Anti-Criticality Device Rapid Prototype

    Science.gov (United States)

    Campbell, Donald R.; Otting, William D.

    1994-07-01

    The Ballistic Missile Defense Organization (BMDO) has been working on a Nuclear Electric Propulsion Space Test Project (NEPSTP) using an existing Russian Topaz II reactor system to power the NEPSTP satellite. Safety investigations have shown that it will be possible to safely launch the Topaz II system in the United States with some modification to preclude water flooded criticality. A ``fuel-out'' water subcriticality concept was selected by the Los Alamos National Laboratory (LANL) as the baseline concept. A fuel-out anti-criticality device (ACD) conceptual design was developed by Rockwell. The concept functions to hold the fuel from the four centermost thermionic fuel elements (TFEs) outside the reactor during launch and reliably inserts the fuel into the reactor once the operational orbit is achieved. A four-tenths scale ACD rapid prototype model, fabricated from the CATIA solids design model, clearly shows in three dimensions the relative size and spatial relationship of the ACD components.

  14. Software Prototyping

    Science.gov (United States)

    Del Fiol, Guilherme; Hanseler, Haley; Crouch, Barbara Insley; Cummins, Mollie R.

    2016-01-01

    Summary Background Health information exchange (HIE) between Poison Control Centers (PCCs) and Emergency Departments (EDs) could improve care of poisoned patients. However, PCC information systems are not designed to facilitate HIE with EDs; therefore, we are developing specialized software to support HIE within the normal workflow of the PCC using user-centered design and rapid prototyping. Objective To describe the design of an HIE dashboard and the refinement of user requirements through rapid prototyping. Methods Using previously elicited user requirements, we designed low-fidelity sketches of designs on paper with iterative refinement. Next, we designed an interactive high-fidelity prototype and conducted scenario-based usability tests with end users. Users were asked to think aloud while accomplishing tasks related to a case vignette. After testing, the users provided feedback and evaluated the prototype using the System Usability Scale (SUS). Results Survey results from three users provided useful feedback that was then incorporated into the design. After achieving a stable design, we used the prototype itself as the specification for development of the actual software. Benefits of prototyping included having 1) subject-matter experts heavily involved with the design; 2) flexibility to make rapid changes, 3) the ability to minimize software development efforts early in the design stage; 4) rapid finalization of requirements; 5) early visualization of designs; 6) and a powerful vehicle for communication of the design to the programmers. Challenges included 1) time and effort to develop the prototypes and case scenarios; 2) no simulation of system performance; 3) not having all proposed functionality available in the final product; and 4) missing needed data elements in the PCC information system. PMID:27081404

  15. Rapid prototyping of microfluidic systems using a PDMS/polymer tape composite.

    Science.gov (United States)

    Kim, Jungkyu; Surapaneni, Rajesh; Gale, Bruce K

    2009-05-07

    Rapid prototyping of microfluidic systems using a combination of double-sided tape and PDMS (polydimethylsiloxane) is introduced. PDMS is typically difficult to bond using adhesive tapes due to its hydrophobic nature and low surface energy. For this reason, PDMS is not compatible with the xurography method, which uses a knife plotter and various adhesive coated polymer tapes. To solve these problems, a PDMS/tape composite was developed and demonstrated in microfluidic applications. The PDMS/tape composite was created by spinning it to make a thin layer of PDMS over double-sided tape. Then the PDMS/tape composite was patterned to create channels using xurography, and bonded to a PDMS slab. After removing the backing paper from the tape, a complete microfluidic system could be created by placing the construct onto nearly any substrate; including glass, plastic or metal-coated glass/silicon substrates. The bond strength was shown to be sufficient for the pressures that occur in typical microfluidic channels used for chemical or biological analysis. This method was demonstrated in three applications: standard microfluidic channels and reactors, a microfluidic system with an integrated membrane, and an electrochemical biosensor. The PDMS/tape composite rapid prototyping technique provides a fast and cost effective fabrication method and can provide easy integration of microfluidic channels with sensors and other components without the need for a cleanroom facility.

  16. Rapid prototyping tools and methods for all-Topas (R) cyclic olefin copolymer fluidic microsystems

    DEFF Research Database (Denmark)

    Bundgaard, Frederik; Perozziello, Gerardo; Geschke, Oliver

    2006-01-01

    , good machinability, and good optical properties. A number of different processes for rapid and low-cost prototyping of all-Topas microfluidic systems, made with desktop machinery, are presented. Among the processes are micromilling of fluidic structures with a width down to 25 p,m and sealing...

  17. New Strategies for Powder Compaction in Powder-based Rapid Prototyping Techniques

    OpenAIRE

    Budding, A.; Vaneker, T.H.J.

    2013-01-01

    In powder-based rapid prototyping techniques, powder compaction is used to create thin layers of fine powder that are locally bonded. By stacking these layers of locally bonded material, an object is made. The compaction of thin layers of powder mater ials is of interest for a wide range of applications, but this study solely focuses on the application for powder -based three-dimensional printing (e.g. SLS, 3DP). This research is primarily interested in powder compaction for creating membrane...

  18. Combined use of rapid-prototyping model and surgical guide in correction of mandibular asymmetry malformation patients with normal occlusal relationship.

    Science.gov (United States)

    Xu, Haisong; Zhang, Ce; Shim, Yoong Hoon; Li, Hongliang; Cao, Dejun

    2015-03-01

    The aim of this study is to discuss the application of rapid-prototyping model and surgical guide in the treatment of mandibular asymmetry malformation with normal occlusal relationship. Twenty-four mandibular asymmetry malformation patients with relatively normal occlusal relationship were included in this study. Surgical 3-dimensional rapid-prototyping mandibular models were made for all patients from the computed tomography (CT) DICOM data. The presurgical plan was designed on the model, and the surgical guiders for the osteotomy lines were manufactured. Genioplasty and/or mandibular osteotomy based on the presurgical plan were performed on these patients with the combined use of the rapid-prototyping model and surgical guides. All patients underwent postoperative CT scan and had at least 3-month follow-up. All patients were satisfied with the final results. According to the postoperative CT images and 3-month follow-up, all patients' mandibular asymmetry malformation was significantly improved, and the operation time was distinctly shortened relative to the conventional method. Rapid-prototyping model and surgical guide are viable auxiliary devices for the treatment of mandibular asymmetry malformation with relatively normal occlusal relationship. Combined use of them can make precise preoperative design, improve effects of operation, and shorten operating time.

  19. A three-dimensional mediastinal model created with rapid prototyping in a patient with ectopic thymoma.

    Science.gov (United States)

    Akiba, Tadashi; Nakada, Takeo; Inagaki, Takuya

    2015-01-01

    Preoperative three-dimensional (3D) imaging of a mediastinal tumor using two-dimensional (2D) axial computed tomography is sometimes difficult, and an unexpected appearance of the tumor may be encountered during surgery. In order to evaluate the preoperative feasibility of a 3D mediastinal model that used the rapid prototyping technique, we created a model and report its results. The 2D image showed some of the relationship between the tumor and the pericardium, but the 3D mediastinal model that was created using the rapid prototyping technique showed the 3D lesion in the outer side of the extrapericardium. The patient underwent a thoracoscopic resection of the tumor, and the pathological examination showed a rare middle mediastinal ectopic thymoma. We believe that the construction of mediastinal models is useful for thoracoscopic surgery and other complicated surgeries of the chest diseases.

  20. A microcontroller platform for the rapid prototyping of functional electrical stimulation-based gait neuroprostheses.

    Science.gov (United States)

    Luzio de Melo, Paulo; da Silva, Miguel Tavares; Martins, Jorge; Newman, Dava

    2015-05-01

    Functional electrical stimulation (FES) has been used over the last decades as a method to rehabilitate lost motor functions of individuals with spinal cord injury, multiple sclerosis, and post-stroke hemiparesis. Within this field, researchers in need of developing FES-based control solutions for specific disabilities often have to choose between either the acquisition and integration of high-performance industry-level systems, which are rather expensive and hardly portable, or develop custom-made portable solutions, which despite their lower cost, usually require expert-level electronic skills. Here, a flexible low-cost microcontroller-based platform for rapid prototyping of FES neuroprostheses is presented, designed for reduced execution complexity, development time, and production cost. For this reason, the Arduino open-source microcontroller platform was used, together with off-the-shelf components whenever possible. The developed system enables the rapid deployment of portable FES-based gait neuroprostheses, being flexible enough to allow simple open-loop strategies but also more complex closed-loop solutions. The system is based on a modular architecture that allows the development of optimized solutions depending on the desired FES applications, even though the design and testing of the platform were focused toward drop foot correction. The flexibility of the system was demonstrated using two algorithms targeting drop foot condition within different experimental setups. Successful bench testing of the device in healthy subjects demonstrated these neuroprosthesis platform capabilities to correct drop foot. Copyright © 2015 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  1. Low-cost rapid prototyping of flexible plastic paper based microfluidic devices

    KAUST Repository

    Fan, Yiqiang

    2013-04-01

    This research presents a novel rapid prototyping method for paper-based flexible microfluidic devices. The microchannels were fabricated using laser ablation on a piece of plastic paper (permanent paper), the dimensions of the microchannels was carefully studied for various laser powers and scanning speeds. After laser ablation of the microchannels on the plastic paper, a transparent poly (methyl methacrylate)(PMMA) film was thermally bonded to the plastic paper to enclose the channels. After connection of tubing, the device was ready to use. An example microfluidic device (droplet generator) was also fabricated using this technique. Due to the flexibility of the fabricated device, this technique can be used to fabricate 3D microfluidic devices. The fabrication process was simple and rapid without any requirement of cleanroom facilities. © 2013 IEEE.

  2. Rapid Prototyping Technologies and their Applications in Prosthodontics, a Review of Literature

    Science.gov (United States)

    Torabi, Kianoosh; Farjood, Ehsan; Hamedani, Shahram

    2015-01-01

    The early computer-aided design/computer-aided manufacturing (CAD/CAM) systems were relied exclusively on subtractive methods. In recent years, additive methods by employing rapid prototyping (RP) have progressed rapidly in various fields of dentistry as they have the potential to overcome known drawbacks of subtractive techniques such as fit problems. RP techniques have been exploited to build complex 3D models in medicine since the 1990s. RP has recently proposed successful applications in various dental fields, such as fabrication of implant surgical guides, frameworks for fixed and removable partial dentures, wax patterns for the dental prosthesis, zirconia prosthesis and molds for metal castings, and maxillofacial prosthesis and finally, complete dentures. This paper aimed to offer a comprehensive literature review of various RP methods, particularly in dentistry, that are expected to bring many improvements to the field. A search was made through MEDLINE database and Google scholar search engine. The keywords; ‘rapid prototyping’ and ‘dentistry’ were searched in title/abstract of publications; limited to 2003 to 2013, concerning past decade. The inclusion criterion was the technical researches that predominately included laboratory procedures. The exclusion criterion was meticulous clinical and excessive technical procedures. A total of 106 articles were retrieved, recited by authors and only 50 met the specified inclusion criteria for this review. Selected articles had used rapid prototyping techniques in various fields in dentistry through different techniques. This review depicted the different laboratory procedures employed in this method and confirmed that RP technique have been substantially feasible in dentistry. With advancement in various RP systems, it is possible to benefit from this technique in different dental practices, particularly in implementing dental prostheses for different applications. PMID:25759851

  3. Rapid Prototyping Modules for Remote Engineering Applications

    Directory of Open Access Journals (Sweden)

    Karsten Henke

    2008-07-01

    Full Text Available This contribution describes the concept and implementation for an integration of microcontroller and FPGA based Rapid Prototyping modules into a Remote Lab system. This implementation enables a Web-based access to electro-mechanical models. A student uploads a source file implementation to the Remote Lab server in order to test an implementation directly within a hardware environment. The Remote Lab server offers the interfaces to integrate specific project and hardware plug-ins. These plug-ins access a hardware specific software environment to automatically compile and program the resulting firmware. To stimulate this design, the Remote Lab server exchanges digital signals via a serial interface. To allow the student to compare architectures of different designs using the same hardware model, a specific controller (using the Remote Lab interface can be selected. For this, an IP-based multiplexer provides the control connection between the respective controller and the hardware model. In our contribution we would like to give examples of such a complex design task and how the students can use different tools during several design steps.

  4. Creation of an in vitro biomechanical model of the trachea using rapid prototyping.

    Science.gov (United States)

    Walenga, Ross L; Longest, P Worth; Sundaresan, Gobalakrishnan

    2014-06-03

    Previous in vitro models of the airways are either rigid or, if flexible, have not matched in vivo compliance characteristics. Rapid prototyping provides a quickly evolving approach that can be used to directly produce in vitro airway models using either rigid or flexible polymers. The objective of this study was to use rapid prototyping to directly produce a flexible hollow model that matches the biomechanical compliance of the trachea. The airway model consisted of a previously developed characteristic mouth-throat region, the trachea, and a portion of the main bronchi. Compliance of the tracheal region was known from a previous in vivo imaging study that reported cross-sectional areas over a range of internal pressures. The compliance of the tracheal region was matched to the in vivo data for a specific flexible resin by iteratively selecting the thicknesses and other dimensions of tracheal wall components. Seven iterative models were produced and illustrated highly non-linear expansion consisting of initial rapid size increase, a transition region, and continued slower size increase as pressure was increased. Thickness of the esophageal interface membrane and initial trachea indention were identified as key parameters with the final model correctly predicting all phases of expansion within a value of 5% of the in vivo data. Applications of the current biomechanical model are related to endotracheal intubation and include determination of effective mucus suctioning and evaluation of cuff sealing with respect to gases and secretions. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. The utilization of cranial models created using rapid prototyping techniques in the development of models for navigation training.

    Science.gov (United States)

    Waran, V; Pancharatnam, Devaraj; Thambinayagam, Hari Chandran; Raman, Rajagopal; Rathinam, Alwin Kumar; Balakrishnan, Yuwaraj Kumar; Tung, Tan Su; Rahman, Z A

    2014-01-01

    Navigation in neurosurgery has expanded rapidly; however, suitable models to train end users to use the myriad software and hardware that come with these systems are lacking. Utilizing three-dimensional (3D) industrial rapid prototyping processes, we have been able to create models using actual computed tomography (CT) data from patients with pathology and use these models to simulate a variety of commonly performed neurosurgical procedures with navigation systems. To assess the possibility of utilizing models created from CT scan dataset obtained from patients with cranial pathology to simulate common neurosurgical procedures using navigation systems. Three patients with pathology were selected (hydrocephalus, right frontal cortical lesion, and midline clival meningioma). CT scan data following an image-guidance surgery protocol in DIACOM format and a Rapid Prototyping Machine were taken to create the necessary printed model with the corresponding pathology embedded. The ability in registration, planning, and navigation of two navigation systems using a variety of software and hardware provided by these platforms was assessed. We were able to register all models accurately using both navigation systems and perform the necessary simulations as planned. Models with pathology utilizing 3D rapid prototyping techniques accurately reflect data of actual patients and can be used in the simulation of neurosurgical operations using navigation systems. Georg Thieme Verlag KG Stuttgart · New York.

  6. Rapid prototyped porous titanium coated with calcium phosphate as a scaffold for bone tissue engineering.

    NARCIS (Netherlands)

    Lopez, M.A.; Sohier, J.; Gaillard, C.A.J.M.; Quillard, S.; Dorget, M.; Layrolle, P.

    2008-01-01

    High strength porous scaffolds and mesenchymal stem cells are required for bone tissue engineering applications. Porous titanium scaffolds (TiS) with a regular array of interconnected pores of 1000 microm in diameter and a porosity of 50% were produced using a rapid prototyping technique. A calcium

  7. Utilizing a Rapid Prototyping Approach in the Building of a Hypermedia-Based Reference Station.

    Science.gov (United States)

    Sell, Dan

    This paper discusses the building of a hypermedia-based reference station at the Wright Laboratory Technical Library, Wright-Patterson Air Force Base, Ohio. Following this, the paper focuses on an electronic user survey from which data is collected and analysis is made. The survey data is used in a rapid prototyping approach, which is defined as…

  8. Rapid world modeling

    International Nuclear Information System (INIS)

    Little, Charles; Jensen, Ken

    2002-01-01

    Sandia National Laboratories has designed and developed systems capable of large-scale, three-dimensional mapping of unstructured environments in near real time. This mapping technique is called rapid world modeling and has proven invaluable when used by prototype systems consisting of sensory detection devices mounted on mobile platforms. These systems can be deployed into previously unmapped environments and transmit real-time 3-D visual images to operators located remotely. This paper covers a brief history of the rapid world modeling system, its implementation on mobile platforms, and the current state of the technology. Applications to the nuclear power industry are discussed. (author)

  9. Micromachining Lithium Niobate for Rapid Prototyping of Resonant Biosensors

    International Nuclear Information System (INIS)

    Al-Shibaany, Zeyad Yousif Abdoon; Hedley, John; Huo, Dehong; Hu, Zhongxu

    2014-01-01

    Lithium niobate material is widely used in MEMS application due to its piezoelectric properties. This paper presents the micromachining process of lithium niobate to rapid prototype a resonant biosensor design. A high precision CNC machine was used to machine a sample of lithium niobate material at 5 different spindle speeds to find out the best conditions to machine this brittle material. A qualitative visual check of the surface was performed by using scanning electron microscopy, surface roughness was quantitatively investigated using an optical surface profiler and Raman spectroscopy to check the strain of the surface. Results show that the surface quality of the lithium niobate was significantly affected by the spindle speed with optimum conditions at 70k rpm giving a strained surface with 500 nm rms roughness

  10. Simulation of the fissureless technique for thoracoscopic segmentectomy using rapid prototyping.

    Science.gov (United States)

    Akiba, Tadashi; Nakada, Takeo; Inagaki, Takuya

    2015-01-01

    The fissureless lobectomy or anterior fissureless technique is a novel surgical technique, which avoids dissection of the lung parenchyma over the pulmonary artery during lobectomy by open thoracotomy approach or direct vision thoracoscopic surgery. This technique is indicated for fused lobes. We present two cases where thoracoscopic pulmonary segmentectomy was performed using the fissureless technique simulated by three-dimensional (3D) pulmonary models. The 3D model and rapid prototyping provided an accurate anatomical understanding of the operative field in both cases. We believe that the construction of these models is useful for thoracoscopic and other complicated surgeries of the chest.

  11. Simulation of the Fissureless Technique for Thoracoscopic Segmentectomy Using Rapid Prototyping

    Science.gov (United States)

    Nakada, Takeo; Inagaki, Takuya

    2014-01-01

    The fissureless lobectomy or anterior fissureless technique is a novel surgical technique, which avoids dissection of the lung parenchyma over the pulmonary artery during lobectomy by open thoracotomy approach or direct vision thoracoscopic surgery. This technique is indicated for fused lobes. We present two cases where thoracoscopic pulmonary segmentectomy was performed using the fissureless technique simulated by three-dimensional (3D) pulmonary models. The 3D model and rapid prototyping provided an accurate anatomical understanding of the operative field in both cases. We believe that the construction of these models is useful for thoracoscopic and other complicated surgeries of the chest. PMID:24633132

  12. Mirror-Imaged Rapid Prototype Skull Model and Pre-Molded Synthetic Scaffold to Achieve Optimal Orbital Cavity Reconstruction.

    Science.gov (United States)

    Park, Sung Woo; Choi, Jong Woo; Koh, Kyung S; Oh, Tae Suk

    2015-08-01

    Reconstruction of traumatic orbital wall defects has evolved to restore the original complex anatomy with the rapidly growing use of computer-aided design and prototyping. This study evaluated a mirror-imaged rapid prototype skull model and a pre-molded synthetic scaffold for traumatic orbital wall reconstruction. A single-center retrospective review was performed of patients who underwent orbital wall reconstruction after trauma from 2012 to 2014. Patients were included by admission through the emergency department after facial trauma or by a tertiary referral for post-traumatic orbital deformity. Three-dimensional (3D) computed tomogram-based mirror-imaged reconstruction images of the orbit and an individually manufactured rapid prototype skull model by a 3D printing technique were obtained for each case. Synthetic scaffolds were anatomically pre-molded using the skull model as guide and inserted at the individual orbital defect. Postoperative complications were assessed and 3D volumetric measurements of the orbital cavity were performed. Paired samples t test was used for statistical analysis. One hundred four patients with immediate orbital defect reconstructions and 23 post-traumatic orbital deformity reconstructions were included in this study. All reconstructions were successful without immediate postoperative complications, although there were 10 cases with mild enophthalmos and 2 cases with persistent diplopia. Reoperations were performed for 2 cases of persistent diplopia and secondary touchup procedures were performed to contour soft tissue in 4 cases. Postoperative volumetric measurement of the orbital cavity showed nonsignificant volume differences between the damaged orbit and the reconstructed orbit (21.35 ± 1.93 vs 20.93 ± 2.07 cm(2); P = .98). This protocol was extended to severe cases in which more than 40% of the orbital frame was lost and combined with extensive soft tissue defects. Traumatic orbital reconstruction can be optimized and

  13. Rapid prototyping modelling in oral and maxillofacial surgery: A two year retrospective study.

    Science.gov (United States)

    Suomalainen, Anni; Stoor, Patricia; Mesimäki, Karri; Kontio, Risto K

    2015-12-01

    The use of rapid prototyping (RP) models in medicine to construct bony models is increasing. The aim of the study was to evaluate retrospectively the indication for the use of RP models in oral and maxillofacial surgery at Helsinki University Central Hospital during 2009-2010. Also, the used computed tomography (CT) examination - multislice CT (MSCT) or cone beam CT (CBCT) - method was evaluated. In total 114 RP models were fabricated for 102 patients. The mean age of the patients at the time of the production of the model was 50.4 years. The indications for the modelling included malignant lesions (29%), secondary reconstruction (25%), prosthodontic treatment (22%), orthognathic surgery or asymmetry (13%), benign lesions (8%), and TMJ disorders (4%). MSCT examination was used in 92 and CBCT examination in 22 cases. Most of the models (75%) were conventional hard tissue models. Models with colored tumour or other structure(s) of interest were ordered in 24%. Two out of the 114 models were soft tissue models. The main benefit of the models was in treatment planning and in connection with the production of pre-bent plates or custom made implants. The RP models both facilitate and improve treatment planning and intraoperative efficiency. Rapid prototyping, radiology, computed tomography, cone beam computed tomography.

  14. Micro rapid prototyping system for micro components

    International Nuclear Information System (INIS)

    Li Xiaochun; Choi Hongseok; Yang Yong

    2002-01-01

    Similarities between silicon-based micro-electro-mechanical systems (MEMS) and Shape Deposition Manufacturing (SDM) processes are obvious: both integrate additive and subtractive processes and use part and sacrificial materials to obtain functional structures. These MEMS techniques are two-dimensional (2-D) processes for a limited number of materials while SDM enables the building of parts that have traditionally been impossible to fabricate because of their complex shapes or of their variety in materials. This work presents initial results on the development of a micro rapid prototyping system that adapts SDM methodology to micro-fabrication. This system is designed to incorporate microdeposition and laser micromachining. In the hope of obtaining a precise microdeposition, an ultrasonic-based micro powder-feeding mechanism was developed in order to form thin patterns of dry powders that can be cladded or sintered onto a substrate by a micro-sized laser beam. Furthermore, experimental results on laser micromachining using a laser beam with a wavelength of 355 nm are also presented. After further improvement, the developed micro manufacturing system could take computer-aided design (CAD) output to reproduce 3-D heterogeneous micro-components from a wide selection of materials

  15. Prompt and Precise Prototyping

    Science.gov (United States)

    2003-01-01

    For Sanders Design International, Inc., of Wilton, New Hampshire, every passing second between the concept and realization of a product is essential to succeed in the rapid prototyping industry where amongst heavy competition, faster time-to-market means more business. To separate itself from its rivals, Sanders Design aligned with NASA's Marshall Space Flight Center to develop what it considers to be the most accurate rapid prototyping machine for fabrication of extremely precise tooling prototypes. The company's Rapid ToolMaker System has revolutionized production of high quality, small-to-medium sized prototype patterns and tooling molds with an exactness that surpasses that of computer numerically-controlled (CNC) machining devices. Created with funding and support from Marshall under a Small Business Innovation Research (SBIR) contract, the Rapid ToolMaker is a dual-use technology with applications in both commercial and military aerospace fields. The advanced technology provides cost savings in the design and manufacturing of automotive, electronic, and medical parts, as well as in other areas of consumer interest, such as jewelry and toys. For aerospace applications, the Rapid ToolMaker enables fabrication of high-quality turbine and compressor blades for jet engines on unmanned air vehicles, aircraft, and missiles.

  16. An FPGA-based rapid prototyping platform for wavelet coprocessors

    Science.gov (United States)

    Vera, Alonzo; Meyer-Baese, Uwe; Pattichis, Marios

    2007-04-01

    MatLab/Simulink-based design flows are being used by DSP designers to improve time-to-market of FPGA implementations. 1 Commonly, digital signal processing cores are integrated in an embedded system as coprocessors. Existing CAD tools do not fully address the integration of a DSP coprocessor into an embedded system design. This integration might prove to be time consuming and error prone. It also requires that the DSP designer has an excellent knowledge of embedded systems and computer architecture details. We present a prototyping platform and design flow that allows rapid integration of embedded systems with a wavelet coprocessor. The platform comprises of software and hardware modules that allow a DSP designer a painless integration of a coprocessor with a PowerPC-based embedded system. The platform has a wide range of applications, from industrial to educational environments.

  17. Rapid prototyping compliant arterial phantoms for in-vitro studies and device testing

    Directory of Open Access Journals (Sweden)

    Biglino Giovanni

    2013-01-01

    Full Text Available Abstract Background Compliant vascular phantoms are desirable for in-vitro patient-specific experiments and device testing. TangoPlus FullCure 930® is a commercially available rubber-like material that can be used for PolyJet rapid prototyping. This work aims to gather preliminary data on the distensibility of this material, in order to assess the feasibility of its use in the context of experimental cardiovascular modelling. Methods The descending aorta anatomy of a volunteer was modelled in 3D from cardiovascular magnetic resonance (CMR images and rapid prototyped using TangoPlus. The model was printed with a range of increasing wall thicknesses (0.6, 0.7, 0.8, 1.0 and 1.5 mm, keeping the lumen of the vessel constant. Models were also printed in both vertical and horizontal orientations, thus resulting in a total of ten specimens. Compliance tests were performed by monitoring pressure variations while gradually increasing and decreasing internal volume. Knowledge of distensibility was thus derived and then implemented with CMR data to test two applications. Firstly, a patient-specific compliant model of hypoplastic aorta suitable for connection in a mock circulatory loop for in-vitro tests was manufactured. Secondly, the right ventricular outflow tract (RVOT of a patient necessitating pulmonary valve replacement was printed in order to physically test device insertion and assess patient’s suitability for percutaneous pulmonary valve intervention. Results The distensibility of the material was identified in a range from 6.5 × 10-3 mmHg-1 for the 0.6 mm case, to 3.0 × 10-3 mmHg-1 for the 1.5 mm case. The models printed in the vertical orientation were always more compliant than their horizontal counterpart. Rapid prototyping of a compliant hypoplastic aorta and of a RVOT anatomical model were both feasible. Device insertion in the RVOT model was successful. Conclusion Values of distensibility, compared with literature data, show that Tango

  18. Rapid prototyping compliant arterial phantoms for in-vitro studies and device testing.

    Science.gov (United States)

    Biglino, Giovanni; Verschueren, Peter; Zegels, Raf; Taylor, Andrew M; Schievano, Silvia

    2013-01-16

    Compliant vascular phantoms are desirable for in-vitro patient-specific experiments and device testing. TangoPlus FullCure 930 is a commercially available rubber-like material that can be used for PolyJet rapid prototyping. This work aims to gather preliminary data on the distensibility of this material, in order to assess the feasibility of its use in the context of experimental cardiovascular modelling. The descending aorta anatomy of a volunteer was modelled in 3D from cardiovascular magnetic resonance (CMR) images and rapid prototyped using TangoPlus. The model was printed with a range of increasing wall thicknesses (0.6, 0.7, 0.8, 1.0 and 1.5 mm), keeping the lumen of the vessel constant. Models were also printed in both vertical and horizontal orientations, thus resulting in a total of ten specimens. Compliance tests were performed by monitoring pressure variations while gradually increasing and decreasing internal volume. Knowledge of distensibility was thus derived and then implemented with CMR data to test two applications. Firstly, a patient-specific compliant model of hypoplastic aorta suitable for connection in a mock circulatory loop for in-vitro tests was manufactured. Secondly, the right ventricular outflow tract (RVOT) of a patient necessitating pulmonary valve replacement was printed in order to physically test device insertion and assess patient's suitability for percutaneous pulmonary valve intervention. The distensibility of the material was identified in a range from 6.5 × 10(-3) mmHg(-1) for the 0.6 mm case, to 3.0 × 10(-3) mmHg(-1) for the 1.5 mm case. The models printed in the vertical orientation were always more compliant than their horizontal counterpart. Rapid prototyping of a compliant hypoplastic aorta and of a RVOT anatomical model were both feasible. Device insertion in the RVOT model was successful. Values of distensibility, compared with literature data, show that TangoPlus is suitable for manufacturing arterial phantoms, with

  19. Effects of Hydrocarbon-Based Grease on Rapid Prototype Material Used for Grease Retention Shrouds

    Science.gov (United States)

    Zakrajsek, Andrew J.; Valco, Daniel J.; Street, Kenneth W., Jr.

    2010-01-01

    Effects of hydrocarbon-based greases on specific rapid prototype (RP) materials used to fabricate grease retention shrouds (GRS) were explored in this study. Grease retention shrouds are being considered as a way to maintain adequate grease lubrication at the gear mesh in a prototype research transmission system. Due to their design and manufacturing flexibility, rapid prototype materials were chosen for the grease retention shrouds. In order to gain a better understanding of the short and long term effects grease pose on RP materials, research was conducted on the interaction of hydrocarbon-based grease with RP materials. The materials used in this study were durable polyamide (nylon), acrylonitrile butadiene styrene (ABS), and WaterClear 10120. Testing was conducted using Mobilgrease 28 and Syn-Tech 3913G grease (gear coupling grease). These greases were selected due to their regular use with mechanical components. To investigate the effect that grease has on RP materials, the following methods were used to obtain qualitative and quantitative data: Fourier transform infrared spectroscopy (FT-IR), interference profilometer measurements, digital camera imaging, physical shape measurement, and visual observations. To record the changes in the RP materials due to contact with the grease, data was taken before and after the grease application. Results showed that the WaterClear 10120 RP material provided the best resistance to grease penetration as compared to nylon and ABS RP materials. The manufacturing process, and thus resulting surface conditions of the RP material, played a key role in the grease penetration properties and resilience of these materials.

  20. Dimensional Error in Rapid Prototyping with Open Source Software and Low-cost 3D-printer.

    Science.gov (United States)

    Rendón-Medina, Marco A; Andrade-Delgado, Laura; Telich-Tarriba, Jose E; Fuente-Del-Campo, Antonio; Altamirano-Arcos, Carlos A

    2018-01-01

    Rapid prototyping models (RPMs) had been extensively used in craniofacial and maxillofacial surgery, especially in areas such as orthognathic surgery, posttraumatic or oncological reconstructions, and implantology. Economic limitations are higher in developing countries such as Mexico, where resources dedicated to health care are limited, therefore limiting the use of RPM to few selected centers. This article aims to determine the dimensional error of a low-cost fused deposition modeling 3D printer (Tronxy P802MA, Shenzhen, Tronxy Technology Co), with Open source software. An ordinary dry human mandible was scanned with a computed tomography device. The data were processed with open software to build a rapid prototype with a fused deposition machine. Linear measurements were performed to find the mean absolute and relative difference. The mean absolute and relative difference was 0.65 mm and 1.96%, respectively ( P = 0.96). Low-cost FDM machines and Open Source Software are excellent options to manufacture RPM, with the benefit of low cost and a similar relative error than other more expensive technologies.

  1. Dimensional Error in Rapid Prototyping with Open Source Software and Low-cost 3D-printer

    Directory of Open Access Journals (Sweden)

    Marco A. Rendón-Medina

    2018-01-01

    Full Text Available Summary:. Rapid prototyping models (RPMs had been extensively used in craniofacial and maxillofacial surgery, especially in areas such as orthognathic surgery, posttraumatic or oncological reconstructions, and implantology. Economic limitations are higher in developing countries such as Mexico, where resources dedicated to health care are limited, therefore limiting the use of RPM to few selected centers. This article aims to determine the dimensional error of a low-cost fused deposition modeling 3D printer (Tronxy P802MA, Shenzhen, Tronxy Technology Co, with Open source software. An ordinary dry human mandible was scanned with a computed tomography device. The data were processed with open software to build a rapid prototype with a fused deposition machine. Linear measurements were performed to find the mean absolute and relative difference. The mean absolute and relative difference was 0.65 mm and 1.96%, respectively (P = 0.96. Low-cost FDM machines and Open Source Software are excellent options to manufacture RPM, with the benefit of low cost and a similar relative error than other more expensive technologies.

  2. Rapid prototyping modelling in oral and maxillofacial surgery: a two year retrospective study

    OpenAIRE

    Suomalainen, Anni; Stoor, Patricia; Mesimäki, Karri; Kontio, Risto K.

    2015-01-01

    Background The use of rapid prototyping (RP) models in medicine to construct bony models is increasing. Material and Methods The aim of the study was to evaluate retrospectively the indication for the use of RP models in oral and maxillofacial surgery at Helsinki University Central Hospital during 2009-2010. Also, the used computed tomography (CT) examination ? multislice CT (MSCT) or cone beam CT (CBCT) - method was evaluated. Results In total 114 RP models were fabricated for 102 patients. ...

  3. Rapid prototyping systems for the development of new fuel-injection concepts for diesel engines; Einspritz-Prototyping-System zur Entwicklung neuer Einspritzkonzepte bei Dieselmotoren

    Energy Technology Data Exchange (ETDEWEB)

    Kasper, M. [ETAS GmbH, Stuttgart (Germany)

    2004-10-01

    The article uses the example of solenoid-based fuel injectors for diesel engines to demonstrate how a combination of reconfigurable logic and microcontrollers may be employed towards the rapid implementation of new control concepts for timely testing either directly on the engine or in the vehicle. Emphasis is given to the development and optimization of electronic engine management components. In contrast to the nonexistent modification options on conventional production ECUs, the new concept allows for the modification and fine-tuning of a number of injection parameters. The rapid prototyping system is a joint development of the Research and Advanced Engineering Department of Robert Bosch GmbH and ETAS GmbH. (orig.)

  4. Rapid Prototyping Human Interfaces Using Stretchable Strain Sensor

    Directory of Open Access Journals (Sweden)

    Tokiya Yamaji

    2017-01-01

    Full Text Available In the modern society with a variety of information electronic devices, human interfaces increase their importance in a boundary of a human and a device. In general, the human is required to get used to the device. Even if the device is designed as a universal device or a high-usability device, the device is not suitable for all users. The usability of the device depends on the individual user. Therefore, personalized and customized human interfaces are effective for the user. To create customized interfaces, we propose rapid prototyping human interfaces using stretchable strain sensors. The human interfaces comprise parts formed by a three-dimensional printer and the four strain sensors. The three-dimensional printer easily makes customized human interfaces. The outputs of the interface are calculated based on the sensor’s lengths. Experiments evaluate three human interfaces: a sheet-shaped interface, a sliding lever interface, and a tilting lever interface. We confirm that the three human interfaces obtain input operations with a high accuracy.

  5. A Rapid Prototyping Environment for Cooperative Advanced Driver Assistance Systems

    Directory of Open Access Journals (Sweden)

    Kay Massow

    2018-01-01

    Full Text Available Advanced Driver Assistance Systems (ADAS were strong innovation drivers in recent years, towards the enhancement of traffic safety and efficiency. Today’s ADAS adopt an autonomous approach with all instrumentation and intelligence on board of one vehicle. However, to further enhance their benefit, ADAS need to cooperate in the future, using communication technologies. The resulting combination of vehicle automation and cooperation, for instance, enables solving hazardous situations by a coordinated safety intervention on multiple vehicles at the same point in time. Since the complexity of such cooperative ADAS grows with each vehicle involved, very large parameter spaces need to be regarded during their development, which necessitate novel development approaches. In this paper, we present an environment for rapidly prototyping cooperative ADAS based on vehicle simulation. Its underlying approach is either to bring ideas for cooperative ADAS through the prototyping stage towards plausible candidates for further development or to discard them as quickly as possible. This is enabled by an iterative process of refining and assessment. We reconcile the aspects of automation and cooperation in simulation by a tradeoff between precision and scalability. Reducing precise mapping of vehicle dynamics below the limits of driving dynamics enables simulating multiple vehicles at the same time. In order to validate this precision, we also present a method to validate the vehicle dynamics in simulation against real world vehicles.

  6. Rapid prototyping of biodegradable microneedle arrays by integrating CO2 laser processing and polymer molding

    International Nuclear Information System (INIS)

    Tu, K T; Chung, C K

    2016-01-01

    An integrated technology of CO 2 laser processing and polymer molding has been demonstrated for the rapid prototyping of biodegradable poly-lactic-co-glycolic acid (PLGA) microneedle arrays. Rapid and low-cost CO 2 laser processing was used for the fabrication of a high-aspect-ratio microneedle master mold instead of conventional time-consuming and expensive photolithography and etching processes. It is crucial to use flexible polydimethylsiloxane (PDMS) to detach PLGA. However, the direct CO 2 laser-ablated PDMS could generate poor surfaces with bulges, scorches, re-solidification and shrinkage. Here, we have combined the polymethyl methacrylate (PMMA) ablation and two-step PDMS casting process to form a PDMS female microneedle mold to eliminate the problem of direct ablation. A self-assembled monolayer polyethylene glycol was coated to prevent stiction between the two PDMS layers during the peeling-off step in the PDMS-to-PDMS replication. Then the PLGA microneedle array was successfully released by bending the second-cast PDMS mold with flexibility and hydrophobic property. The depth of the polymer microneedles can range from hundreds of micrometers to millimeters. It is linked to the PMMA pattern profile and can be adjusted by CO 2 laser power and scanning speed. The proposed integration process is maskless, simple and low-cost for rapid prototyping with a reusable mold. (paper)

  7. Rapid prototyping of biodegradable microneedle arrays by integrating CO2 laser processing and polymer molding

    Science.gov (United States)

    Tu, K. T.; Chung, C. K.

    2016-06-01

    An integrated technology of CO2 laser processing and polymer molding has been demonstrated for the rapid prototyping of biodegradable poly-lactic-co-glycolic acid (PLGA) microneedle arrays. Rapid and low-cost CO2 laser processing was used for the fabrication of a high-aspect-ratio microneedle master mold instead of conventional time-consuming and expensive photolithography and etching processes. It is crucial to use flexible polydimethylsiloxane (PDMS) to detach PLGA. However, the direct CO2 laser-ablated PDMS could generate poor surfaces with bulges, scorches, re-solidification and shrinkage. Here, we have combined the polymethyl methacrylate (PMMA) ablation and two-step PDMS casting process to form a PDMS female microneedle mold to eliminate the problem of direct ablation. A self-assembled monolayer polyethylene glycol was coated to prevent stiction between the two PDMS layers during the peeling-off step in the PDMS-to-PDMS replication. Then the PLGA microneedle array was successfully released by bending the second-cast PDMS mold with flexibility and hydrophobic property. The depth of the polymer microneedles can range from hundreds of micrometers to millimeters. It is linked to the PMMA pattern profile and can be adjusted by CO2 laser power and scanning speed. The proposed integration process is maskless, simple and low-cost for rapid prototyping with a reusable mold.

  8. Hypervapotron flow testing with rapid prototype models

    International Nuclear Information System (INIS)

    Driemeyer, D.; Hellwig, T.; Kubik, D.; Langenderfer, E.; Mantz, H.; McSmith, M.; Jones, B.; Butler, J.

    1995-01-01

    A flow test model of the inlet section of a three channel hypervapotron plate that has been proposed as a heat sink in the ITER divertor was prepared using a rapid prototyping stereolithography process that is widely used for component development in US industry. An existing water flow loop at the University of Illinois is being used for isothermal flow tests to collect pressure drop data for comparison with proposed vapotron friction factor correlations. Differential pressure measurements are taken, across the test section inlet manifold, the vapotron channel (about a seven inch length), the outlet manifold and the inlet-to-outlet. The differential pressures are currently measured with manometers. Tests were conducted at flow velocities from 1--10 m/s to cover the full range of ITER interest. A tap was also added for a small hypodermic needle to inject dye into the flow channel at several positions to examine the nature of the developing flow field at the entrance to the vapotron section. Follow-on flow tests are planned using a model with adjustable flow channel dimensions to permit more extensive pressure drop data to be collected. This information will be used to update vapotron design correlations for ITER

  9. A new UV-curing elastomeric substrate for rapid prototyping of microfluidic devices

    Science.gov (United States)

    Alvankarian, Jafar; Yeop Majlis, Burhanuddin

    2012-03-01

    Rapid prototyping in the design cycle of new microfluidic devices is very important for shortening time-to-market. Researchers are facing the challenge to explore new and suitable substrates with simple and efficient microfabrication techniques. In this paper, we introduce and characterize a UV-curing elastomeric polyurethane methacrylate (PUMA) for rapid prototyping of microfluidic devices. The swelling and solubility of PUMA in different chemicals is determined. Time-dependent measurements of water contact angle show that the native PUMA is hydrophilic without surface treatment. The current monitoring method is used for measurement of the electroosmotic flow mobility in the microchannels made from PUMA. The optical, physical, thermal and mechanical properties of PUMA are evaluated. The UV-lithography and molding process is used for making micropillars and deep channel microfluidic structures integrated to the supporting base layer. Spin coating is characterized for producing different layer thicknesses of PUMA resin. A device is fabricated and tested for examining the strength of different bonding techniques such as conformal, corona treating and semi-curing of two PUMA layers in microfluidic application and the results show that the bonding strengths are comparable to that of PDMS. We also report fabrication and testing of a three-layer multi inlet/outlet microfluidic device including a very effective fluidic interconnect for application demonstration of PUMA as a promising new substrate. A simple micro-device is developed and employed for observing the pressure deflection of membrane made from PUMA as a very effective elastomeric valve in microfluidic devices.

  10. Rapid Control Prototyping and PIL Co-Simulation of a Quadrotor UAV Based on NI myRIO-1900 Board

    OpenAIRE

    Soufiene Bouallègue; Rabii Fessi

    2016-01-01

    In this paper, a new Computer Aided Design (CAD) methodology for the Processor-In-the-Loop (PIL) co-simulation and Rapid Control Prototyping (RCP) of a Quadrotor Vertical Take-Off and Landing (VTOL) type of Unmanned Arial Vehicle (UAV) is proposed and successfully implemented around an embedded NI myRIO-1900 target and a host PC. The developed software (SW) and hardware (HW) prototyping platform is based on the Control Design and Simulation (CDSim) module of LabVIEW environment and an establi...

  11. Rapid sealing of porcine renal blood vessels, ex vivo, using a high power, 1470-nm laser, and laparoscopic prototype

    Science.gov (United States)

    Hardy, Luke A.; Hutchens, Thomas C.; Larson, Eric R.; Gonzalez, David A.; Chang, Chun-Hung; Nau, William H.; Fried, Nathaniel M.

    2017-05-01

    Energy-based, radiofrequency (RF) and ultrasonic (US) devices currently provide rapid sealing of blood vessels during laparoscopic procedures. We are exploring infrared lasers as an alternate energy modality for vessel sealing, capable of generating less collateral thermal damage. Previous studies demonstrated feasibility of sealing vessels in an in vivo porcine model using a 1470-nm laser. However, the initial prototype was designed for testing in open surgery and featured tissue clasping and light delivery mechanisms incompatible with laparoscopic surgery. In this study, a laparoscopic prototype similar to devices currently in surgical use was developed, and performance tests were conducted on porcine renal blood vessels, ex vivo. The 5-mm outer-diameter laparoscopic prototype featured a traditional Maryland jaw configuration that enables tissue manipulation and blunt dissection. Laser energy was delivered through a 550-μm-core-diameter optical fiber with side-delivery from the lower jaw and beam dimensions of 18-mm length×1.2-mm width. The 1470-nm diode laser delivered 68 W with 3-s activation time, consistent with vessel seal times associated with RF and US-based devices. A total of 69 fresh porcine renal vessels with mean diameter of 3.3±1.7 mm were tested, ex vivo. Vessels smaller than 5-mm diameter were consistently sealed (48/51) with burst pressures greater than malignant hypertension blood pressure (180 mmHg), averaging 1038±474 mmHg. Vessels larger than 5 mm were not consistently sealed (6/18), yielding burst pressures of only 174±221 mmHg. Seal width, thermal damage zone, and thermal spread averaged 1.7±0.8, 3.4±0.7, and 1.0±0.4 mm, respectively. Results demonstrated that the 5-mm optical laparoscopic prototype consistently sealed vessels less than 5-mm diameter with low thermal spread. Further in vivo studies are planned to test the performance across a variety of vessels and tissues.

  12. Rapid and Low-cost Prototyping of Medical Devices Using 3D Printed Molds for Liquid Injection Molding

    Science.gov (United States)

    Chung, Philip; Heller, J. Alex; Etemadi, Mozziyar; Ottoson, Paige E.; Liu, Jonathan A.; Rand, Larry; Roy, Shuvo

    2014-01-01

    Biologically inert elastomers such as silicone are favorable materials for medical device fabrication, but forming and curing these elastomers using traditional liquid injection molding processes can be an expensive process due to tooling and equipment costs. As a result, it has traditionally been impractical to use liquid injection molding for low-cost, rapid prototyping applications. We have devised a method for rapid and low-cost production of liquid elastomer injection molded devices that utilizes fused deposition modeling 3D printers for mold design and a modified desiccator as an injection system. Low costs and rapid turnaround time in this technique lower the barrier to iteratively designing and prototyping complex elastomer devices. Furthermore, CAD models developed in this process can be later adapted for metal mold tooling design, enabling an easy transition to a traditional injection molding process. We have used this technique to manufacture intravaginal probes involving complex geometries, as well as overmolding over metal parts, using tools commonly available within an academic research laboratory. However, this technique can be easily adapted to create liquid injection molded devices for many other applications. PMID:24998993

  13. Selected laboratory evaluations of the whole-water sample-splitting capabilities of a prototype fourteen-liter Teflon churn splitter

    Science.gov (United States)

    Horowitz, A.J.; Smith, J.J.; Elrick, K.A.

    2001-01-01

    A prototype 14-L Teflon? churn splitter was evaluated for whole-water sample-splitting capabilities over a range of sediment concentratons and grain sizes as well as for potential chemical contamination from both organic and inorganic constituents. These evaluations represent a 'best-case' scenario because they were performed in the controlled environment of a laboratory, and used monomineralic silica sand slurries of known concentration made up in deionized water. Further, all splitting was performed by a single operator, and all the requisite concentration analyses were performed by a single laboratory. The prototype Teflon? churn splitter did not appear to supply significant concentrations of either organic or inorganic contaminants at current U.S. Geological Survey (USGS) National Water Quality Laboratory detection and reporting limits when test samples were prepared using current USGS protocols. As with the polyethylene equivalent of the prototype Teflon? churn, the maximum usable whole-water suspended sediment concentration for the prototype churn appears to lie between 1,000 and 10,000 milligrams per liter (mg/L). Further, the maximum grain-size limit appears to lie between 125- and 250-microns (m). Tests to determine the efficacy of the valve baffle indicate that it must be retained to facilitate representative whole-water subsampling.

  14. Rapid prototyping of 2D glass microfluidic devices based on femtosecond laser assisted selective etching process

    Science.gov (United States)

    Kim, Sung-Il; Kim, Jeongtae; Koo, Chiwan; Joung, Yeun-Ho; Choi, Jiyeon

    2018-02-01

    Microfluidics technology which deals with small liquid samples and reagents within micro-scale channels has been widely applied in various aspects of biological, chemical, and life-scientific research. For fabricating microfluidic devices, a silicon-based polymer, PDMS (Polydimethylsiloxane), is widely used in soft lithography, but it has several drawbacks for microfluidic applications. Glass has many advantages over PDMS due to its excellent optical, chemical, and mechanical properties. However, difficulties in fabrication of glass microfluidic devices that requires multiple skilled steps such as MEMS technology taking several hours to days, impedes broad application of glass based devices. Here, we demonstrate a rapid and optical prototyping of a glass microfluidic device by using femtosecond laser assisted selective etching (LASE) and femtosecond laser welding. A microfluidic droplet generator was fabricated as a demonstration of a microfluidic device using our proposed prototyping. The fabrication time of a single glass chip containing few centimeter long and complex-shaped microfluidic channels was drastically reduced in an hour with the proposed laser based rapid and simple glass micromachining and hermetic packaging technique.

  15. Rapid Prototyping with Fourth Generation Systems - an Empirical Study

    DEFF Research Database (Denmark)

    Grønbæk, Kaj

    1989-01-01

    Discusses experiences on the development and use of horizontal and vertical prototypes. Explains the difference. Resolves that horizontal prototypes can be developed with 'little effort', but end users are reluctant to become involved in the development process. Contrastingly resolves that vertical...... prototypes appear to stimulate constructive response. Reasons that developers should be aware of the tacit knowledge which plays an important part in users' work practices and should be involved early in the development process. Proposes three techniques to meet the requirements – participation, simulation...

  16. The Java Image Science Toolkit (JIST) for Rapid Prototyping and Publishing of Neuroimaging Software

    Science.gov (United States)

    Lucas, Blake C.; Bogovic, John A.; Carass, Aaron; Bazin, Pierre-Louis; Prince, Jerry L.; Pham, Dzung

    2010-01-01

    Non-invasive neuroimaging techniques enable extraordinarily sensitive and specific in vivo study of the structure, functional response and connectivity of biological mechanisms. With these advanced methods comes a heavy reliance on computer-based processing, analysis and interpretation. While the neuroimaging community has produced many excellent academic and commercial tool packages, new tools are often required to interpret new modalities and paradigms. Developing custom tools and ensuring interoperability with existing tools is a significant hurdle. To address these limitations, we present a new framework for algorithm development that implicitly ensures tool interoperability, generates graphical user interfaces, provides advanced batch processing tools, and, most importantly, requires minimal additional programming or computational overhead. Java-based rapid prototyping with this system is an efficient and practical approach to evaluate new algorithms since the proposed system ensures that rapidly constructed prototypes are actually fully-functional processing modules with support for multiple GUI's, a broad range of file formats, and distributed computation. Herein, we demonstrate MRI image processing with the proposed system for cortical surface extraction in large cross-sectional cohorts, provide a system for fully automated diffusion tensor image analysis, and illustrate how the system can be used as a simulation framework for the development of a new image analysis method. The system is released as open source under the Lesser GNU Public License (LGPL) through the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC). PMID:20077162

  17. The Java Image Science Toolkit (JIST) for rapid prototyping and publishing of neuroimaging software.

    Science.gov (United States)

    Lucas, Blake C; Bogovic, John A; Carass, Aaron; Bazin, Pierre-Louis; Prince, Jerry L; Pham, Dzung L; Landman, Bennett A

    2010-03-01

    Non-invasive neuroimaging techniques enable extraordinarily sensitive and specific in vivo study of the structure, functional response and connectivity of biological mechanisms. With these advanced methods comes a heavy reliance on computer-based processing, analysis and interpretation. While the neuroimaging community has produced many excellent academic and commercial tool packages, new tools are often required to interpret new modalities and paradigms. Developing custom tools and ensuring interoperability with existing tools is a significant hurdle. To address these limitations, we present a new framework for algorithm development that implicitly ensures tool interoperability, generates graphical user interfaces, provides advanced batch processing tools, and, most importantly, requires minimal additional programming or computational overhead. Java-based rapid prototyping with this system is an efficient and practical approach to evaluate new algorithms since the proposed system ensures that rapidly constructed prototypes are actually fully-functional processing modules with support for multiple GUI's, a broad range of file formats, and distributed computation. Herein, we demonstrate MRI image processing with the proposed system for cortical surface extraction in large cross-sectional cohorts, provide a system for fully automated diffusion tensor image analysis, and illustrate how the system can be used as a simulation framework for the development of a new image analysis method. The system is released as open source under the Lesser GNU Public License (LGPL) through the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC).

  18. Learning Over Time: Using Rapid Prototyping Generative Analysis Experts and Reduction of Scope to Operationalize Design

    Science.gov (United States)

    2010-05-04

    during the Vietnam Conflict. 67 David A. Kolb , Experiential Learning : Experience as the Source of Learning and Development. (Upper Saddle River, NJ...Essentials for Military Applications. Newport Paper #10. Newport: Newport War College Press. 1996. Kolb , David A. Experiential Learning : Experience... learning over analysis. A broad review of design theory suggests that four techniques - rapid prototyping, generative analysis, use of experts, and

  19. Rapid prototyping of robotic platforms

    CSIR Research Space (South Africa)

    De Ronde, Willis

    2016-11-01

    Full Text Available of thickness up to 200mm can be cut to create prototype chassis/ bodies or even the final product. One of the few limitations is the cutting of certain laminated materials, as this tends to produce delaminated cutting edges or even fractures in the case... mine inspection robot (Shongololo). Shongololo’s frame is made from engineering plastics while the chassis of Dassie was made from aluminium and cut using abrasive waterjet machining. The advantage of using abrasive waterjet machining is the speed...

  20. Rapid prototyping of flexible intrafascicular electrode arrays by picosecond laser structuring.

    Science.gov (United States)

    Mueller, Matthias; de la Oliva, Natalia; Del Valle, Jaume; Delgado-Martínez, Ignacio; Navarro, Xavier; Stieglitz, Thomas

    2017-12-01

    Interfacing the peripheral nervous system can be performed with a large variety of electrode arrays. However, stimulating and recording a nerve while having a reasonable amount of channels limits the number of available systems. Translational research towards human clinical trial requires device safety and biocompatibility but would benefit from design flexibility in the development process to individualize probes. We selected established medical grade implant materials like precious metals and Parylene C to develop a rapid prototyping process for novel intrafascicular electrode arrays using a picosecond laser structuring. A design for a rodent animal model was developed in conjunction with an intrafascicular implantation strategy. Electrode characterization and optimization was performed first in saline solution in vitro before performance and biocompatibility were validated in sciatic nerves of rats in chronic implantation. The novel fabrication process proved to be suitable for prototyping and building intrafascicular electrode arrays. Electrochemical properties of the electrode sites were enhanced and tested for long-term stability. Chronic implantation in the sciatic nerve of rats showed good biocompatibility, selectivity and stable stimulation thresholds. Established medical grade materials can be used for intrafascicular nerve electrode arrays when laser structuring defines structure size in the micro-scale. Design flexibility reduces re-design cycle time and material certificates are beneficial support for safety studies on the way to clinical trials.

  1. Rapid prototyping of flexible intrafascicular electrode arrays by picosecond laser structuring

    Science.gov (United States)

    Mueller, Matthias; de la Oliva, Natalia; del Valle, Jaume; Delgado-Martínez, Ignacio; Navarro, Xavier; Stieglitz, Thomas

    2017-12-01

    Objective. Interfacing the peripheral nervous system can be performed with a large variety of electrode arrays. However, stimulating and recording a nerve while having a reasonable amount of channels limits the number of available systems. Translational research towards human clinical trial requires device safety and biocompatibility but would benefit from design flexibility in the development process to individualize probes. Approach. We selected established medical grade implant materials like precious metals and Parylene C to develop a rapid prototyping process for novel intrafascicular electrode arrays using a picosecond laser structuring. A design for a rodent animal model was developed in conjunction with an intrafascicular implantation strategy. Electrode characterization and optimization was performed first in saline solution in vitro before performance and biocompatibility were validated in sciatic nerves of rats in chronic implantation. Main results. The novel fabrication process proved to be suitable for prototyping and building intrafascicular electrode arrays. Electrochemical properties of the electrode sites were enhanced and tested for long-term stability. Chronic implantation in the sciatic nerve of rats showed good biocompatibility, selectivity and stable stimulation thresholds. Significance. Established medical grade materials can be used for intrafascicular nerve electrode arrays when laser structuring defines structure size in the micro-scale. Design flexibility reduces re-design cycle time and material certificates are beneficial support for safety studies on the way to clinical trials.

  2. Indirect rapid prototyping of antibacterial acid anhydride copolymer microneedles

    International Nuclear Information System (INIS)

    Boehm, Ryan D; Miller, Philip R; Singh, Ritika; Narayan, Roger J; Shah, Akash; Stafslien, Shane; Daniels, Justin

    2012-01-01

    Microneedles are needle-like projections with microscale features that may be used for transdermal delivery of a variety of pharmacologic agents, including antibacterial agents. In the study described in this paper, an indirect rapid prototyping approach involving a combination of visible light dynamic mask micro-stereolithography and micromolding was used to prepare microneedle arrays out of a biodegradable acid anhydride copolymer, Gantrez® AN 169 BF. Fourier transform infrared spectroscopy, energy dispersive x-ray spectrometry and nanoindentation studies were performed to evaluate the chemical and mechanical properties of the Gantrez® AN 169 BF material. Agar plating studies were used to evaluate the in vitro antimicrobial performance of these arrays against Bacillus subtilis, Candida albicans, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. Large zones of growth inhibition were noted for Escherichia coli, S. aureus, Enterococcus faecalis and B. subtilis. The performance of Gantrez® AN 169 BF against several bacteria suggests that biodegradable acid anhydride copolymer microneedle arrays prepared using visible light dynamic mask micro-stereolithography micromolding may be useful for treating a variety of skin infections. (communication)

  3. Accuracy of using computer-aided rapid prototyping templates for mandible reconstruction with an iliac crest graft

    Science.gov (United States)

    2014-01-01

    Background This study aimed to evaluate the accuracy of surgical outcomes in free iliac crest mandibular reconstructions that were carried out with virtual surgical plans and rapid prototyping templates. Methods This study evaluated eight patients who underwent mandibular osteotomy and reconstruction with free iliac crest grafts using virtual surgical planning and designed guiding templates. Operations were performed using the prefabricated guiding templates. Postoperative three-dimensional computer models were overlaid and compared with the preoperatively designed models in the same coordinate system. Results Compared to the virtual osteotomy, the mean error of distance of the actual mandibular osteotomy was 2.06 ± 0.86 mm. When compared to the virtual harvested grafts, the mean error volume of the actual harvested grafts was 1412.22 ± 439.24 mm3 (9.12% ± 2.84%). The mean error between the volume of the actual harvested grafts and the shaped grafts was 2094.35 ± 929.12 mm3 (12.40% ± 5.50%). Conclusions The use of computer-aided rapid prototyping templates for virtual surgical planning appears to positively influence the accuracy of mandibular reconstruction. PMID:24957053

  4. Plug-and-play paper-based toolkit for rapid prototyping of microfluidics and electronics towards point-of-care diagnostic solutions

    CSIR Research Space (South Africa)

    Smith, S

    2015-11-01

    Full Text Available We present a plug-and-play toolkit for the rapid assembly of paper-based microfluidic and electronic components for quick prototyping of paper-based components towards point-of-care diagnostic solutions. Individual modules, each with a specific...

  5. A Case Series of Rapid Prototyping and Intraoperative Imaging in Orbital Reconstruction

    Science.gov (United States)

    Lim, Christopher G.T.; Campbell, Duncan I.; Cook, Nicholas; Erasmus, Jason

    2014-01-01

    In Christchurch Hospital, rapid prototyping (RP) and intraoperative imaging are the standard of care in orbital trauma and has been used since February 2013. RP allows the fabrication of an anatomical model to visualize complex anatomical structures which is dimensionally accurate and cost effective. This assists diagnosis, planning, and preoperative implant adaptation for orbital reconstruction. Intraoperative imaging involves a computed tomography scan during surgery to evaluate surgical implants and restored anatomy and allows the clinician to correct errors in implant positioning that may occur during the same procedure. This article aims to demonstrate the potential clinical and cost saving benefits when both these technologies are used in orbital reconstruction which minimize the need for revision surgery. PMID:26000080

  6. A case series of rapid prototyping and intraoperative imaging in orbital reconstruction.

    Science.gov (United States)

    Lim, Christopher G T; Campbell, Duncan I; Cook, Nicholas; Erasmus, Jason

    2015-06-01

    In Christchurch Hospital, rapid prototyping (RP) and intraoperative imaging are the standard of care in orbital trauma and has been used since February 2013. RP allows the fabrication of an anatomical model to visualize complex anatomical structures which is dimensionally accurate and cost effective. This assists diagnosis, planning, and preoperative implant adaptation for orbital reconstruction. Intraoperative imaging involves a computed tomography scan during surgery to evaluate surgical implants and restored anatomy and allows the clinician to correct errors in implant positioning that may occur during the same procedure. This article aims to demonstrate the potential clinical and cost saving benefits when both these technologies are used in orbital reconstruction which minimize the need for revision surgery.

  7. Virtual Simulator for Autonomous Mobile Robots Navigation System Using Concepts of Control Rapid Prototyping

    Directory of Open Access Journals (Sweden)

    Leonimer Flavio de Melo

    2013-09-01

    Full Text Available This work presents the proposal of virtual environment implementation for project simulation and conception of supervision and control systems for mobile robots, that are capable to operate and adapting in different environments and conditions. This virtual system has as purpose to facilitate the development of embedded architecture systems, emphasizing the implementation of tools that allow the simulation of the kinematic conditions, dynamic and control, with real time monitoring of all important system points. For this, open control architecture is proposal, integrating the two main techniques of robotic control implementation in the hardware level: systems microprocessors and reconfigurable hardware devices. The implemented simulator system is composed of a trajectory generating module, a kinematic and dynamic simulator module and of a analysis module of results and errors. The kinematic and dynamic simulator module makes all simulation of the mobile robot following the pre-determined trajectory of the trajectory generator. All the kinematic and dynamic results shown during the simulation can be evaluated and visualized in graphs and tables formats, in the results analysis module, allowing an improvement in the system, minimizing the errors with the necessary adjustments optimization. For controller implementation in the embedded system, it uses the rapid prototyping, which is the technology that allows, in set with the virtual simulation environment, the development of a controller project for mobile robots. The validation and tests had been accomplishing with nonholonomics mobile robots models with differential transmission.

  8. Rapid, Reliable Shape Setting of Superelastic Nitinol for Prototyping Robots.

    Science.gov (United States)

    Gilbert, Hunter B; Webster, Robert J

    Shape setting Nitinol tubes and wires in a typical laboratory setting for use in superelastic robots is challenging. Obtaining samples that remain superelastic and exhibit desired precurvatures currently requires many iterations, which is time consuming and consumes a substantial amount of Nitinol. To provide a more accurate and reliable method of shape setting, in this paper we propose an electrical technique that uses Joule heating to attain the necessary shape setting temperatures. The resulting high power heating prevents unintended aging of the material and yields consistent and accurate results for the rapid creation of prototypes. We present a complete algorithm and system together with an experimental analysis of temperature regulation. We experimentally validate the approach on Nitinol tubes that are shape set into planar curves. We also demonstrate the feasibility of creating general space curves by shape setting a helical tube. The system demonstrates a mean absolute temperature error of 10°C.

  9. A prototype stationary Fourier transform spectrometer for near-infrared absorption spectroscopy.

    Science.gov (United States)

    Li, Jinyang; Lu, Dan-feng; Qi, Zhi-mei

    2015-09-01

    A prototype stationary Fourier transform spectrometer (FTS) was constructed with a fiber-coupled lithium niobate (LiNbO3) waveguide Mach-Zehnder interferometer (MZI) for the purpose of rapid on-site spectroscopy of biological and chemical measurands. The MZI contains push-pull electrodes for electro-optic modulation, and its interferogram as a plot of intensity against voltage was obtained by scanning the modulating voltage from -60 to +60 V in 50 ms. The power spectrum of input signal was retrieved by Fourier transform processing of the interferogram combined with the wavelength dispersion of half-wave voltage determined for the MZI used. The prototype FTS operates in the single-mode wavelength range from 1200 to 1700 nm and allows for reproducible spectroscopy. A linear concentration dependence of the absorbance at λmax = 1451 nm for water in ethanolic solution was obtained using the prototype FTS. The near-infrared spectroscopy of solid samples was also implemented, and the different spectra obtained with different materials evidenced the chemical recognition capability of the prototype FTS. To make this prototype FTS practically applicable, work on improving its spectral resolution by increasing the maximum optical path length difference is in progress.

  10. A comparison of different silver inks for printing of conductive tracks on paper substrates for rapid prototyping of electronic circuits

    CSIR Research Space (South Africa)

    Bezuidenhout, PH

    2015-11-01

    Full Text Available This study compares the performance between two commercially-available electrically conductive silver inks, Harima NPS-J nanopaste and the NBSIJ-FD02 Mitsubishi conductive ink, used in rapid prototyping of electronic circuits. The comparative...

  11. Development of novel hybrid poly(l-lactide)/chitosan scaffolds using the rapid freeze prototyping technique

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, N; Chen, X B [Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, Saskatchewan (Canada); Li, M G [Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, Saskatchewan (Canada); Cooper, D, E-mail: xbc719@mail.usask.ca [Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, Saskatchewan (Canada)

    2011-09-15

    Engineered scaffolds have been shown to be critical to various tissue engineering applications. This paper presents the development of a novel three-dimensional scaffold made from a mixture of chitosan microspheres (CMs) and poly(l-lactide) by means of the rapid freeze prototyping (RFP) technique. The CMs were used to encapsulate bovine serum albumin (BSA) and improve the scaffold mechanical properties. Experiments to examine the BSA release were carried out; the BSA release could be controlled by adjusting the crosslink degree of the CMs and prolonged after the CMs were embedded into the PLLA scaffolds, while the examination of the mechanical properties of the scaffolds illustrates that they depend on the ratio of CMs to PLLA in the scaffolds as well as the cryogenic temperature used in the RFP fabrication process. The chemical characteristics of the PLLA/chitosan scaffolds were evaluated by Fourier transform infrared (FTIR) spectroscopy. The morphological and pore structure of the scaffolds were also examined by scanning electron microscopy and micro-tomography. The results obtained show that the scaffolds have higher porosity and enhanced pore size distribution compared to those fabricated by the dispensing-based rapid prototyping technique. This study demonstrates that the novel scaffolds have not only enhanced porous structure and mechanical properties but also showed the potential to preserve the bioactivities of the biomolecules and to control the biomolecule distribution and release rate.

  12. Communication and logging hub for rapid prototyping of environmental sensors: presenting the Smartphone.

    Science.gov (United States)

    Hut, R.

    2017-12-01

    When desiging prototype sensors for environmental variables a critical step is a comparison campaign where the new sensor is compared to current state of the art sensors. In this step one of the headaches for researchers can be connecting their sensor to a logging or communication device. I present a simple solution: to use smartphone that scans for Bluetooth Low Energy transmissions and uploads any measurement to a data server. In this way the prototype sensor only has to transmit its measurement values over BLE, which can be done using off-the-shelf components. The sensors don't have to be physically connected to the phone, allowing for very rapid deployment of sensors in locations that have a communication hub (ie. phone) installed. The communication and logging hub consists of nothing more than a low cost Android smartphone running a dedicated app. The phone is encased in a waterproof box with a large powerbank and a solar panel. I will demonstrate this live at the Fall Meeting. By installing these phones along permanent WMO certified station locations, comparisons campaigns can use the "golden standard" from the WMO without much problems.

  13. Photogrammetry for rapid prototyping: development of noncontact 3D reconstruction technologies

    Science.gov (United States)

    Knyaz, Vladimir A.

    2002-04-01

    An important stage of rapid prototyping technology is generating computer 3D model of an object to be reproduced. Wide variety of techniques for 3D model generation exists beginning with manual 3D models generation and finishing with full-automated reverse engineering system. The progress in CCD sensors and computers provides the background for integration of photogrammetry as an accurate 3D data source with CAD/CAM. The paper presents the results of developing photogrammetric methods for non-contact spatial coordinates measurements and generation of computer 3D model of real objects. The technology is based on object convergent images processing for calculating its 3D coordinates and surface reconstruction. The hardware used for spatial coordinates measurements is based on PC as central processing unit and video camera as image acquisition device. The original software for Windows 9X realizes the complete technology of 3D reconstruction for rapid input of geometry data in CAD/CAM systems. Technical characteristics of developed systems are given along with the results of applying for various tasks of 3D reconstruction. The paper describes the techniques used for non-contact measurements and the methods providing metric characteristics of reconstructed 3D model. Also the results of system application for 3D reconstruction of complex industrial objects are presented.

  14. Reusable Rapid Prototyped Blunt Impact Simulator

    Science.gov (United States)

    2016-08-01

    of a few weeks instead of the months it would have taken to prototype and pursue a conventionally manufactured solution. 3. Future Work In the...NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Douglas A Petrick 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER...impact area geometries were manufactured using selective laser sintering RP technology. These projectiles were launched with a compressed air cannon

  15. Three-dimensional pulmonary model using rapid-prototyping in patient with lung cancer requiring segmentectomy.

    Science.gov (United States)

    Akiba, Tadashi; Nakada, Takeo; Inagaki, Takuya

    2014-01-01

    Thoracoscopic pulmonary segmentectomy of the lung is sometime adopted for the lung cancer, but a problem with segmentectomy is variable anatomy. Recently, we are exploring the impact of three-dimensional models using rapid-prototyping technique. It is useful for decision making, surgical planning, and intraoperative orientation for surgical treatment in patient with lung cancer who underwent pulmonary segmentectomy. These newly created models allow us to clearly identify the surgical margin and the intersegmental plane, vessels, and bronchi related to the cancer in the posterior segment. To the best of our knowledge, there are few reports describing a pulmonary model so far.

  16. An Introduction to Rapid System Prototyping

    OpenAIRE

    Luqi; Kordon, Fabrice

    2002-01-01

    IEEE Transactions on Software Engineering, Vol. 28, No. 9, pp. 817–821. The implementation and maintenance of industrial applications have continuously become more and more difficult. In this context, one problem is the evaluation of complex systems. The IEEE defines Prototyping as a development approach promoting the implementation of a pilot version of the intended product. This approach is a potential solution to the early evaluation of a system. It can also be used to avoid th...

  17. MITRE sensor layer prototype

    Science.gov (United States)

    Duff, Francis; McGarry, Donald; Zasada, David; Foote, Scott

    2009-05-01

    The MITRE Sensor Layer Prototype is an initial design effort to enable every sensor to help create new capabilities through collaborative data sharing. By making both upstream (raw) and downstream (processed) sensor data visible, users can access the specific level, type, and quantities of data needed to create new data products that were never anticipated by the original designers of the individual sensors. The major characteristic that sets sensor data services apart from typical enterprise services is the volume (on the order of multiple terabytes) of raw data that can be generated by most sensors. Traditional tightly coupled processing approaches extract pre-determined information from the incoming raw sensor data, format it, and send it to predetermined users. The community is rapidly reaching the conclusion that tightly coupled sensor processing loses too much potentially critical information.1 Hence upstream (raw and partially processed) data must be extracted, rapidly archived, and advertised to the enterprise for unanticipated uses. The authors believe layered sensing net-centric integration can be achieved through a standardize-encapsulate-syndicateaggregate- manipulate-process paradigm. The Sensor Layer Prototype's technical approach focuses on implementing this proof of concept framework to make sensor data visible, accessible and useful to the enterprise. To achieve this, a "raw" data tap between physical transducers associated with sensor arrays and the embedded sensor signal processing hardware and software has been exploited. Second, we encapsulate and expose both raw and partially processed data to the enterprise within the context of a service-oriented architecture. Third, we advertise the presence of multiple types, and multiple layers of data through geographic-enabled Really Simple Syndication (GeoRSS) services. These GeoRSS feeds are aggregated, manipulated, and filtered by a feed aggregator. After filtering these feeds to bring just the type

  18. Comparison of reconstructed rapid prototyping models produced by 3-dimensional printing and conventional stone models with different degrees of crowding.

    Science.gov (United States)

    Wan Hassan, Wan Nurazreena; Yusoff, Yusnilawati; Mardi, Noor Azizi

    2017-01-01

    Rapid prototyping models can be reconstructed from stereolithographic digital study model data to produce hard-copy casts. In this study, we aimed to compare agreement and accuracy of measurements made with rapid prototyping and stone models for different degrees of crowding. The Z Printer 450 (3D Systems, Rock Hill, SC) reprinted 10 sets of models for each category of crowding (mild, moderate, and severe) scanned using a structured-light scanner (Maestro 3D, AGE Solutions, Pisa, Italy). Stone and RP models were measured using digital calipers for tooth sizes in the mesiodistal, buccolingual, and crown height planes and for arch dimension measurements. Bland-Altman and paired t test analyses were used to assess agreement and accuracy. Clinical significance was set at ±0.50 mm. Bland-Altman analysis showed the mean bias of measurements between the models to be within ±0.15 mm (SD, ±0.40 mm), but the 95% limits of agreement exceeded the cutoff point of ±0.50 mm (lower range, -0.81 to -0.41 mm; upper range, 0.34 to 0.76 mm). Paired t tests showed statistically significant differences for all planes in all categories of crowding except for crown height in the moderate crowding group and arch dimensions in the mild and moderate crowding groups. The rapid prototyping models were not clinically comparable with conventional stone models regardless of the degree of crowding. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  19. Rapid Prototyping of Standard Compliant Visible Light Communications System

    OpenAIRE

    Gavrincea, Ciprian; Baranda, Jorge; Henarejos, Pol

    2014-01-01

    This article describes the implementation of a prototype visible light communications system based on the IEEE 802.15.7 standard using low-cost commercial off-the-shelf analog devices. The aim of this article is to show that this standard provides a framework that could promote the introduction of applications into the market. Thus, these specifications could be further developed, reducing the gap between the industry and research communities. The implemented prototype makes use of software d...

  20. Prototyping for surgical and prosthetic treatment.

    Science.gov (United States)

    Goiato, Marcelo Coelho; Santos, Murillo Rezende; Pesqueira, Aldiéris Alves; Moreno, Amália; dos Santos, Daniela Micheline; Haddad, Marcela Filié

    2011-05-01

    Techniques of rapid prototyping were introduced in the 1980s in the field of engineering for the fabrication of a solid model based on a computed file. After its introduction in the biomedical field, several applications were raised for the fabrication of models to ease surgical planning and simulation in implantology, neurosurgery, and orthopedics, as well as for the fabrication of maxillofacial prostheses. Hence, the literature has described the evolution of rapid prototyping technique in health care, which allowed easier technique, improved surgical results, and fabrication of maxillofacial prostheses. Accordingly, a literature review on MEDLINE (PubMed) database was conducted using the keywords rapid prototyping, surgical planning, and maxillofacial prostheses and based on articles published from 1981 to 2010. After reading the titles and abstracts of the articles, 50 studies were selected owing to their correlations with the aim of the current study. Several studies show that the prototypes have been used in different dental-medical areas such as maxillofacial and craniofacial surgery; implantology; neurosurgery; orthopedics; scaffolds of ceramic, polymeric, and metallic materials; and fabrication of personalized maxillofacial prostheses. Therefore, prototyping has been an indispensable tool in several studies and helpful for surgical planning and fabrication of prostheses and implants.

  1. Design and rapid prototyping of DLC coated fractal surfaces for tissue engineering applications

    International Nuclear Information System (INIS)

    Diaz-Lantada, A; Mosquera, A; Endrino, J L; Lafont, P

    2010-01-01

    Several medical devices (both implantable and for in vitro diagnosis) benefit greatly from having microtextured surfaces that help to improve and promote phenomena such as osteointegracion and cell / tissue growth on the surface of a device. Normally, the use of abrasives or chemical attacks are employed for obtaining such surface microtextures, however, it is sometimes difficult to precisely control the final surface characteristics (porosity, roughness, among others) and consequently the related biological aspects. In this work, we propose an alternative process based on the use of fractal surface models for designing special surfaces, which helps controlling the desired contact properties (from the design stage) in multiple applications within biomedical engineering, especially regarding tissue engineering tasks. Manufacturing can be directly accomplished by means of rapid prototyping technologies. This method supposes a focus change from a conventional 'top-down' to a more versatile 'bottom-up' approach. Finally, in order to improve the possible biological response, the surfaces of the designed devices were coated with hydrogen-free amorphous carbon (a-C) thin films, known to be highly biocompatible materials. The films were deposited at room temperature using the vacuum filter cathodic arc technique. Our first prototypes have helped verify the viability of the approach and to validate the design, manufacturing and coating processes.

  2. Design and rapid prototyping of DLC coated fractal surfaces for tissue engineering applications

    Energy Technology Data Exchange (ETDEWEB)

    Diaz-Lantada, A; Mosquera, A; Endrino, J L; Lafont, P, E-mail: adiaz@etsii.upm.es

    2010-11-01

    Several medical devices (both implantable and for in vitro diagnosis) benefit greatly from having microtextured surfaces that help to improve and promote phenomena such as osteointegracion and cell / tissue growth on the surface of a device. Normally, the use of abrasives or chemical attacks are employed for obtaining such surface microtextures, however, it is sometimes difficult to precisely control the final surface characteristics (porosity, roughness, among others) and consequently the related biological aspects. In this work, we propose an alternative process based on the use of fractal surface models for designing special surfaces, which helps controlling the desired contact properties (from the design stage) in multiple applications within biomedical engineering, especially regarding tissue engineering tasks. Manufacturing can be directly accomplished by means of rapid prototyping technologies. This method supposes a focus change from a conventional 'top-down' to a more versatile 'bottom-up' approach. Finally, in order to improve the possible biological response, the surfaces of the designed devices were coated with hydrogen-free amorphous carbon (a-C) thin films, known to be highly biocompatible materials. The films were deposited at room temperature using the vacuum filter cathodic arc technique. Our first prototypes have helped verify the viability of the approach and to validate the design, manufacturing and coating processes.

  3. A study on embedded resistor components fabricated by laser micro-cladding and rapid prototype

    International Nuclear Information System (INIS)

    Li Huiling; Zeng Xiaoyan

    2006-01-01

    With the rapid development of IC and packaging, electronic devices are required to be smaller, to have a high-density integration, to become multifunction and to be of lower cost and high-reliability. Thick-film technology is not able to meet the current developing demands because of its shortcomings, such as the limit of pattern resolution, the severe torsion and delay of high-speed signal transmission. The speed and quality of signal transmission will be improved if embedded resistor components are directly integrated in the multiplayer substrate of multi-chip or laminated module, and high-density integration and reliability are achieved because the short interconnection and the less soldering point. In this paper, a technique named laser micro-cladding and rapid prototype is used to directly fabricate embedded resistor units on the multiplayer ceramic substrate without using a mask and high-temperature sintering, and without trimming resistor, which will simplify processing and decrease cost as well as improving high-speed and reliable performance

  4. A novel 3D template for mandible and maxilla reconstruction: Rapid prototyping using stereolithography

    Science.gov (United States)

    Kumta, Samir; Kumta, Monica; Jain, Leena; Purohit, Shrirang; Ummul, Rani

    2015-01-01

    Introduction: Replication of the exact three-dimensional (3D) structure of the maxilla and mandible is now a priority whilst attempting reconstruction of these bones to attain a complete functional and aesthetic rehabilitation. We hereby present the process of rapid prototyping using stereolithography to produce templates for modelling bone grafts and implants for maxilla/mandible reconstructions, its applications in tumour/trauma, and outcomes for primary and secondary reconstruction. Materials and Methods: Stereolithographic template-assisted reconstruction was used on 11 patients for the reconstruction of the mandible/maxilla primarily following tumour excision and secondarily for the realignment of post-traumatic malunited fractures or deformity corrections. Data obtained from the computed tomography (CT) scans with 1-mm resolution were converted into a computer-aided design (CAD) using the CT Digital Imaging and Communications in Medicine (DICOM) data. Once a CAD model was constructed, it was converted into a stereolithographic format and then processed by the rapid prototyping technology to produce the physical anatomical model using a resin. This resin model replicates the native mandible, which can be thus used off table as a guide for modelling the bone grafts. Discussion: This conversion of two-dimensional (2D) data from CT scan into 3D models is a very precise guide to shaping the bone grafts. Further, this CAD can reconstruct the defective half of the mandible using the mirror image principle, and the normal anatomical model can be created to aid secondary reconstructions. Conclusion: This novel approach allows a precise translation of the treatment plan directly to the surgical field. It is also an important teaching tool for implant moulding and fixation, and helps in patient counselling. PMID:26933279

  5. A novel 3D template for mandible and maxilla reconstruction: Rapid prototyping using stereolithography.

    Science.gov (United States)

    Kumta, Samir; Kumta, Monica; Jain, Leena; Purohit, Shrirang; Ummul, Rani

    2015-01-01

    Replication of the exact three-dimensional (3D) structure of the maxilla and mandible is now a priority whilst attempting reconstruction of these bones to attain a complete functional and aesthetic rehabilitation. We hereby present the process of rapid prototyping using stereolithography to produce templates for modelling bone grafts and implants for maxilla/mandible reconstructions, its applications in tumour/trauma, and outcomes for primary and secondary reconstruction. Stereolithographic template-assisted reconstruction was used on 11 patients for the reconstruction of the mandible/maxilla primarily following tumour excision and secondarily for the realignment of post-traumatic malunited fractures or deformity corrections. Data obtained from the computed tomography (CT) scans with 1-mm resolution were converted into a computer-aided design (CAD) using the CT Digital Imaging and Communications in Medicine (DICOM) data. Once a CAD model was constructed, it was converted into a stereolithographic format and then processed by the rapid prototyping technology to produce the physical anatomical model using a resin. This resin model replicates the native mandible, which can be thus used off table as a guide for modelling the bone grafts. This conversion of two-dimensional (2D) data from CT scan into 3D models is a very precise guide to shaping the bone grafts. Further, this CAD can reconstruct the defective half of the mandible using the mirror image principle, and the normal anatomical model can be created to aid secondary reconstructions. This novel approach allows a precise translation of the treatment plan directly to the surgical field. It is also an important teaching tool for implant moulding and fixation, and helps in patient counselling.

  6. A novel 3D template for mandible and maxilla reconstruction: Rapid prototyping using stereolithography

    Directory of Open Access Journals (Sweden)

    Samir Kumta

    2015-01-01

    Full Text Available Introduction: Replication of the exact three-dimensional (3D structure of the maxilla and mandible is now a priority whilst attempting reconstruction of these bones to attain a complete functional and aesthetic rehabilitation. We hereby present the process of rapid prototyping using stereolithography to produce templates for modelling bone grafts and implants for maxilla/mandible reconstructions, its applications in tumour/trauma, and outcomes for primary and secondary reconstruction. Materials and Methods: Stereolithographic template-assisted reconstruction was used on 11 patients for the reconstruction of the mandible/maxilla primarily following tumour excision and secondarily for the realignment of post-traumatic malunited fractures or deformity corrections. Data obtained from the computed tomography (CT scans with 1-mm resolution were converted into a computer-aided design (CAD using the CT Digital Imaging and Communications in Medicine (DICOM data. Once a CAD model was constructed, it was converted into a stereolithographic format and then processed by the rapid prototyping technology to produce the physical anatomical model using a resin. This resin model replicates the native mandible, which can be thus used off table as a guide for modelling the bone grafts. Discussion: This conversion of two-dimensional (2D data from CT scan into 3D models is a very precise guide to shaping the bone grafts. Further, this CAD can reconstruct the defective half of the mandible using the mirror image principle, and the normal anatomical model can be created to aid secondary reconstructions. Conclusion: This novel approach allows a precise translation of the treatment plan directly to the surgical field. It is also an important teaching tool for implant moulding and fixation, and helps in patient counselling.

  7. Pediatric Dispersible Tablets: a Modular Approach for Rapid Prototyping.

    Science.gov (United States)

    Buck, Jonas; Huwyler, Jörg; Kühl, Peter; Dischinger, Angela

    2016-08-01

    The design of pediatric formulations is challenging. Solid dosage forms for children have to meet the needs of different ages, e.g. high number of dosing increments and strengths. A modular formulation strategy offering the possibility of rapid prototyping was applied. Different tablet compositions and the resulting tablet characteristics were investigated for dispersible tablets using customized analytical methods. Fluid bed granules were blended with extragranular components, and compressed to tablets. Disintegration behavior was studied with a Texture Analyzer and a Tensiometer. Methods for determination of disintegration time and water uptake of tablets were developed with a Texture Analyzer, and a Tensiometer, respectively. Twenty-two different tablet formulations were prepared and analyzed with respect to disintegration time, hardness, friability, and viscosity. Multivariate data analysis revealed a high impact of type and amount of viscosity enhancer on the disintegration behavior of tablets. An optimized formulation was selected with a disintegration time of 24 s. Methods providing additional information on the disintegration behavior of dispersible tablets compared to standard pharmacopoeia methods were established. Selecting the right type and level of viscosity enhancer and superdisintegrant was critical for developing pediatric tablets with a disintegration time of less than 30 s but still pleasant mouth feel.

  8. Reverse engineering--rapid prototyping of the skull in forensic trauma analysis.

    Science.gov (United States)

    Kettner, Mattias; Schmidt, Peter; Potente, Stefan; Ramsthaler, Frank; Schrodt, Michael

    2011-07-01

    Rapid prototyping (RP) comprises a variety of automated manufacturing techniques such as selective laser sintering (SLS), stereolithography, and three-dimensional printing (3DP), which use virtual 3D data sets to fabricate solid forms in a layer-by-layer technique. Despite a growing demand for (virtual) reconstruction models in daily forensic casework, maceration of the skull is frequently assigned to ensure haptic evidence presentation in the courtroom. Owing to the progress in the field of forensic radiology, 3D data sets of relevant cases are usually available to the forensic expert. Here, we present a first application of RP in forensic medicine using computed tomography scans for the fabrication of an SLS skull model in a case of fatal hammer impacts to the head. The report is intended to show that this method fully respects the dignity of the deceased and is consistent with medical ethics but nevertheless provides an excellent 3D impression of anatomical structures and injuries. © 2011 American Academy of Forensic Sciences.

  9. [The reliability of dento-maxillary models created by cone-beam CT and rapid prototyping:a comparative study].

    Science.gov (United States)

    Lv, Yan; Yan, Bin; Wang, Lin; Lou, Dong-hua

    2012-04-01

    To analyze the reliability of the dento-maxillary models created by cone-beam CT and rapid prototyping (RP). Plaster models were obtained from 20 orthodontic patients who had been scanned by cone-beam CT and 3-D models were formed after the calculation and reconstruction of software. Then, computerized composite models (RP models) were produced by rapid prototyping technique. The crown widths, dental arch widths and dental arch lengths on each plaster model, 3-D model and RP model were measured, followed by statistical analysis with SPSS17.0 software package. For crown widths, dental arch lengths and crowding, there were significant differences(Pmodels, but the dental arch widths were on the contrary. Measurements on 3-D models were significantly smaller than those on other two models(Pmodels, RP models had more numbers which were not significantly different from those on plaster models(P>0.05). The regression coefficient among three models were significantly different(Pmodels was bigger than that between 3-D and plaster models. There is high consistency within 3 models, while some differences were accepted in clinic. Therefore, it is possible to substitute 3-D and RP models for plaster models in order to save storage space and improve efficiency.

  10. Fabrication and Prototyping Lab

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The Fabrication and Prototyping Lab for composite structures provides a wide variety of fabrication capabilities critical to enabling hands-on research and...

  11. Colloidal processing and rapid prototyping of Si{sub 3}N{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Liwu Wang

    1998-12-01

    Some progresses have been made in the wet shaping of Si{sub 3}N{sub 4} based on a better understanding of the colloidal behavior of suspensions and by improved pressure casting with porous polystyrene (PS) molds. This work illustrated that the combination of proper colloidal processing and rapid prototyping is an effective way to fabricate high-performance ceramics with complex shapes. In colloidal processing the packing density and microstructure of green bodies can be controlled if the interaction between ceramic particles in suspensions and the conditions under which the suspensions are consolidated are understood. Therefore, detailed studies on the surface chemistry of the Si{sub 3}N{sub 4} powder, the dispersing behavior of Si{sub 3}N{sub 4} suspensions, the influence of dispersants and the mechanism during powder consolidation into complex-shaped green bodies are performed. (orig.)

  12. Cell-free protein synthesis enabled rapid prototyping for metabolic engineering and synthetic biology

    Directory of Open Access Journals (Sweden)

    Lihong Jiang

    2018-06-01

    Full Text Available Advances in metabolic engineering and synthetic biology have facilitated the manufacturing of many valuable-added compounds and commodity chemicals using microbial cell factories in the past decade. However, due to complexity of cellular metabolism, the optimization of metabolic pathways for maximal production represents a grand challenge and an unavoidable barrier for metabolic engineering. Recently, cell-free protein synthesis system (CFPS has been emerging as an enabling alternative to address challenges in biomanufacturing. This review summarizes the recent progresses of CFPS in rapid prototyping of biosynthetic pathways and genetic circuits (biosensors to speed up design-build-test (DBT cycles of metabolic engineering and synthetic biology. Keywords: Cell-free protein synthesis, Metabolic pathway optimization, Genetic circuits, Metabolic engineering, Synthetic biology

  13. Obtention of hydroxyapatite submicrometric of bovine origin by vibratory grinding for rapid prototyping; Obtencao de hidroxiapatita submicrometrica de origem bovina por moagem vibratoria visando prototipagem rapida

    Energy Technology Data Exchange (ETDEWEB)

    Meira, C.R.; Purquerio, B.M.; Fortulan, C.A., E-mail: camilameira@sc.usp.br [Universidade de Sao Paulo (USP), Sao Carlos, SP (Brazil). Escola de Engenharia; Braga, F.J.C. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    Submicron bovine hydroxyapatite was obtained for rapid prototyping. Hydroxyapatite structure originated from bovine mineral bone has great importance among the biomaterials and biocompatibility due to its great similarity with the human bone structure. This study aims to obtain powder for manufacture by rapid prototyping of scaffolds. This technique manufacture requires highly reactive powders to compensate for the absence of pressure forming. Hydroxyapatite was milled in a ball mill and vibratory mill, and analyzed for their average equivalent spherical diameter and surface area. Test specimens were isostatically pressed at 100 MPa and machined into cylindrical test specimens. These specimens were sintered at several temperatures to determine the optimal sintering temperature based on densification and chemistry stability. In grinding ball mill was obtained particles of equivalent diameter of 0.74 micron in vibratory mill of 0.46 micrometers. An average flexural strength of 100 MPa and 99,8% of real density was attained for the sample sintered at 1300 deg C/2h, signaling potential for use in rapid prototyping. (author)

  14. Stabilized FE simulation of prototype thermal-hydraulics problems with integrated adjoint-based capabilities

    International Nuclear Information System (INIS)

    Shadid, J.N.; Smith, T.M.; Cyr, E.C.; Wildey, T.M.; Pawlowski, R.P.

    2016-01-01

    A critical aspect of applying modern computational solution methods to complex multiphysics systems of relevance to nuclear reactor modeling, is the assessment of the predictive capability of specific proposed mathematical models. In this respect the understanding of numerical error, the sensitivity of the solution to parameters associated with input data, boundary condition uncertainty, and mathematical models is critical. Additionally, the ability to evaluate and or approximate the model efficiently, to allow development of a reasonable level of statistical diagnostics of the mathematical model and the physical system, is of central importance. In this study we report on initial efforts to apply integrated adjoint-based computational analysis and automatic differentiation tools to begin to address these issues. The study is carried out in the context of a Reynolds averaged Navier–Stokes approximation to turbulent fluid flow and heat transfer using a particular spatial discretization based on implicit fully-coupled stabilized FE methods. Initial results are presented that show the promise of these computational techniques in the context of nuclear reactor relevant prototype thermal-hydraulics problems.

  15. Stabilized FE simulation of prototype thermal-hydraulics problems with integrated adjoint-based capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Shadid, J.N., E-mail: jnshadi@sandia.gov [Sandia National Laboratories, Computational Mathematics Department (United States); Department of Mathematics and Statistics, University of New Mexico (United States); Smith, T.M. [Sandia National Laboratories, Multiphysics Applications Department (United States); Cyr, E.C. [Sandia National Laboratories, Computational Mathematics Department (United States); Wildey, T.M. [Sandia National Laboratories, Optimization and UQ Department (United States); Pawlowski, R.P. [Sandia National Laboratories, Multiphysics Applications Department (United States)

    2016-09-15

    A critical aspect of applying modern computational solution methods to complex multiphysics systems of relevance to nuclear reactor modeling, is the assessment of the predictive capability of specific proposed mathematical models. In this respect the understanding of numerical error, the sensitivity of the solution to parameters associated with input data, boundary condition uncertainty, and mathematical models is critical. Additionally, the ability to evaluate and or approximate the model efficiently, to allow development of a reasonable level of statistical diagnostics of the mathematical model and the physical system, is of central importance. In this study we report on initial efforts to apply integrated adjoint-based computational analysis and automatic differentiation tools to begin to address these issues. The study is carried out in the context of a Reynolds averaged Navier–Stokes approximation to turbulent fluid flow and heat transfer using a particular spatial discretization based on implicit fully-coupled stabilized FE methods. Initial results are presented that show the promise of these computational techniques in the context of nuclear reactor relevant prototype thermal-hydraulics problems.

  16. Comportamiento celular en andamios fabricados por rapid prototyping para la ingeniería tisular ósea

    OpenAIRE

    Puech, Laurent

    2013-01-01

    La fabricación de nuevos andamios biodegradables capaces de guiar y estimular la regeneración ósea es un objetivo de gran importancia en la ingeniería de los tejidos. En este sentido, se han desarrollado innovadoras técnicas de conformación como el rapid prototyping para fabricar andamios con geometría y porosidad controlada adaptable según las propiedades del tejido a regenerar. El objetivo de este proyecto es de estudiar el comportamiento celular en andamios poliméricos de...

  17. Technical Note: Rapid prototyping of 3D grid arrays for image guided therapy quality assurance

    International Nuclear Information System (INIS)

    Kittle, David; Holshouser, Barbara; Slater, James M.; Guenther, Bob D.; Pitsianis, Nikos P.; Pearlstein, Robert D.

    2008-01-01

    Three dimensional grid phantoms offer a number of advantages for measuring imaging related spatial inaccuracies for image guided surgery and radiotherapy. The authors examined the use of rapid prototyping technology for directly fabricating 3D grid phantoms from CAD drawings. We tested three different fabrication process materials, photopolymer jet with acrylic resin (PJ/AR), selective laser sintering with polyamide (SLS/P), and fused deposition modeling with acrylonitrile butadiene styrene (FDM/ABS). The test objects consisted of rectangular arrays of control points formed by the intersections of posts and struts (2 mm rectangular cross section) and spaced 8 mm apart in the x, y, and z directions. The PJ/AR phantom expanded after immersion in water which resulted in permanent warping of the structure. The surface of the FDM/ABS grid exhibited a regular pattern of depressions and ridges from the extrusion process. SLS/P showed the best combination of build accuracy, surface finish, and stability. Based on these findings, a grid phantom for assessing machine-dependent and frame-induced MR spatial distortions was fabricated to be used for quality assurance in stereotactic neurosurgical and radiotherapy procedures. The spatial uniformity of the SLS/P grid control point array was determined by CT imaging (0.6x0.6x0.625 mm 3 resolution) and found suitable for the application, with over 97.5% of the control points located within 0.3 mm of the position specified in CAD drawing and none of the points off by more than 0.4 mm. Rapid prototyping is a flexible and cost effective alternative for development of customized grid phantoms for medical physics quality assurance.

  18. [Fabrication of 3-dimensional skull model with rapid prototyping technique and its primary application in repairing one case of cranio-maxillo-facial trauma].

    Science.gov (United States)

    Xia, Delin; Gui, Lai; Zhang, Zhiyong; Lu, Changsheng; Niu, Feng; Jin, Ji; Liu, Xiaoqing

    2005-10-01

    To investigate the methods of establishing 3-dimensional skull model using electron beam CT (EBCT) data rapid prototyping technique, and to discuss its application in repairing cranio-maxillo-facial trauma. The data were obtained by EBCT continuous volumetric scanning with 1.0 mm slice at thickness. The data were transferred to work-station for 3-dimensional surface reconstruction by computer-aided design software and the images were saved as STL file. The data can be used to control a laser rapid-prototyping device (AFS-320QZ) to construct geometric model. The material for the model construction is a kind of laser-sensitive resin power, which will become a mass when scanned by laser beam. The design and simulation of operation can be done on the model. The image data were transferred to the device slice by slice. Thus a geometric model is constructed according to the image data by repeating this process. Preoperative analysis, surgery simulation and implant of bone defect could be done on this computer-aided manufactured 3D model. One case of cranio-maxillo-facial bone defect resulting from trauma was reconstructed with this method. The EBCT scanning showed that the defect area was 4 cm x 6 cm. The nose was flat and deviated to left. The 3-dimensional skull was reconstructed with EBCT data and rapid prototyping technique. The model can display the structure of 3-dimensional anatomy and their relationship. The prefabricated implant by 3-dimensional model was well-matched with defect. The deformities of flat and deviated nose were corrected. The clinical result was satisfactory after a follow-up of 17 months. The 3-dimensional model of skull can replicate the prototype of disease and play an important role in the diagnosis and simulation of operation for repairing cranio-maxillo-facial trauma.

  19. Rapid prototyping of multi-scale biomedical microdevices by combining additive manufacturing technologies.

    Science.gov (United States)

    Hengsbach, Stefan; Lantada, Andrés Díaz

    2014-08-01

    The possibility of designing and manufacturing biomedical microdevices with multiple length-scale geometries can help to promote special interactions both with their environment and with surrounding biological systems. These interactions aim to enhance biocompatibility and overall performance by using biomimetic approaches. In this paper, we present a design and manufacturing procedure for obtaining multi-scale biomedical microsystems based on the combination of two additive manufacturing processes: a conventional laser writer to manufacture the overall device structure, and a direct-laser writer based on two-photon polymerization to yield finer details. The process excels for its versatility, accuracy and manufacturing speed and allows for the manufacture of microsystems and implants with overall sizes up to several millimeters and with details down to sub-micrometric structures. As an application example we have focused on manufacturing a biomedical microsystem to analyze the impact of microtextured surfaces on cell motility. This process yielded a relevant increase in precision and manufacturing speed when compared with more conventional rapid prototyping procedures.

  20. Development of a prototype lateral flow immunoassay (LFI for the rapid diagnosis of melioidosis.

    Directory of Open Access Journals (Sweden)

    Raymond L Houghton

    2014-03-01

    Full Text Available Burkholderia pseudomallei is a soil-dwelling bacterium and the causative agent of melioidosis. Isolation of B. pseudomallei from clinical samples is the "gold standard" for the diagnosis of melioidosis; results can take 3-7 days to produce. Alternatively, antibody-based tests have low specificity due to a high percentage of seropositive individuals in endemic areas. There is a clear need to develop a rapid point-of-care antigen detection assay for the diagnosis of melioidosis. Previously, we employed In vivo Microbial Antigen Discovery (InMAD to identify potential B. pseudomallei diagnostic biomarkers. The B. pseudomallei capsular polysaccharide (CPS and numerous protein antigens were identified as potential candidates. Here, we describe the development of a diagnostic immunoassay based on the detection of CPS. Following production of a CPS-specific monoclonal antibody (mAb, an antigen-capture immunoassay was developed to determine the concentration of CPS within a panel of melioidosis patient serum and urine samples. The same mAb was used to produce a prototype Active Melioidosis Detect Lateral Flow Immunoassay (AMD LFI; the limit of detection of the LFI for CPS is comparable to the antigen-capture immunoassay (∼0.2 ng/ml. The analytical reactivity (inclusivity of the AMD LFI was 98.7% (76/77 when tested against a large panel of B. pseudomallei isolates. Analytical specificity (cross-reactivity testing determined that 97.2% of B. pseudomallei near neighbor species (35/36 were not reactive. The non-reactive B. pseudomallei strain and the reactive near neighbor strain can be explained through genetic sequence analysis. Importantly, we show the AMD LFI is capable of detecting CPS in a variety of patient samples. The LFI is currently being evaluated in Thailand and Australia; the focus is to optimize and validate testing procedures on melioidosis patient samples prior to initiation of a large, multisite pre-clinical evaluation.

  1. A novel low-cost mobile robot for rapid prototyping of precision farming applications

    DEFF Research Database (Denmark)

    Jensen, Kjeld; Neerup, Mathias Mikkel; Larsen, Leon Bonde

    Experimental research in precision farming is a significant challenge due to the considerable resources required to perform field experiments. Simulating the field environment is a frequently used technique which is useful for functional software tests, but beyond that it is necessary to perform...... experiments. In this work we present a novel FrobitPro robot platform designed for rapid prototyping of FroboMind field robot applications. FrobitPro has a fundamental design similar to many current wheeled and tracked robots such as the Kongskilde Robotti, and the workflow of migrating from simulation...... as outdoor driving in semi-rugged terrain such as grass fields and bare soil. This paper presents the FrobitPro robot and describes two use cases in current research projects, namely the Grassbots project which focuses on harvesting of grass on lowland areas for biofuel production and the SAFE project...

  2. Rapid prototyping of biomimetic vascular phantoms for hyperspectral reflectance imaging

    Science.gov (United States)

    Ghassemi, Pejhman; Wang, Jianting; Melchiorri, Anthony J.; Ramella-Roman, Jessica C.; Mathews, Scott A.; Coburn, James C.; Sorg, Brian S.; Chen, Yu; Joshua Pfefer, T.

    2015-12-01

    The emerging technique of rapid prototyping with three-dimensional (3-D) printers provides a simple yet revolutionary method for fabricating objects with arbitrary geometry. The use of 3-D printing for generating morphologically biomimetic tissue phantoms based on medical images represents a potentially major advance over existing phantom approaches. Toward the goal of image-defined phantoms, we converted a segmented fundus image of the human retina into a matrix format and edited it to achieve a geometry suitable for printing. Phantoms with vessel-simulating channels were then printed using a photoreactive resin providing biologically relevant turbidity, as determined by spectrophotometry. The morphology of printed vessels was validated by x-ray microcomputed tomography. Channels were filled with hemoglobin (Hb) solutions undergoing desaturation, and phantoms were imaged with a near-infrared hyperspectral reflectance imaging system. Additionally, a phantom was printed incorporating two disjoint vascular networks at different depths, each filled with Hb solutions at different saturation levels. Light propagation effects noted during these measurements-including the influence of vessel density and depth on Hb concentration and saturation estimates, and the effect of wavelength on vessel visualization depth-were evaluated. Overall, our findings indicated that 3-D-printed biomimetic phantoms hold significant potential as realistic and practical tools for elucidating light-tissue interactions and characterizing biophotonic system performance.

  3. ASSESSMENT OF SURFACE FINISH AND DIMENSIONAL ACCURACY OF TOOLS MANUFACTURED BY METAL CASTING IN RAPID PROTOTYPING SAND MOULDS

    OpenAIRE

    Nyembwe, K.; De Beer, D. J.; Van der Walt, J. G.; Bhero, S.

    2012-01-01

    In this paper, an initial assessment of the quality parameters of the surface finish and dimensional accuracy of tools made by metal casting in rapid prototyping (RP) sand moulds is undertaken. A case study from a local tool room, dealing with the manufacturing of an aluminium die for the lost wax process, is employed. Modern techniques, including surface roughness analysis and three dimensional scanning, are used to determine and understand how each manufacturing step influences the final qu...

  4. A prototype for JDEM science data processing

    International Nuclear Information System (INIS)

    Gottschalk, Erik E

    2011-01-01

    Fermilab is developing a prototype science data processing and data quality monitoring system for dark energy science. The purpose of the prototype is to demonstrate distributed data processing capabilities for astrophysics applications, and to evaluate candidate technologies for trade-off studies. We present the architecture and technical aspects of the prototype, including an open source scientific execution and application development framework, distributed data processing, and publish/subscribe message passing for quality control.

  5. Development and Evaluation of the Virtual Prototype of the First Saudi Arabian-Designed Car

    Directory of Open Access Journals (Sweden)

    Mustufa H. Abidi

    2016-10-01

    Full Text Available Prototyping and evaluation are imperative phases of the present product design and development process. Although digital modeling and analysis methods are widely employed at various product development stages, still, building a physical prototype makes the present typical process expensive and time consuming. Therefore, it is necessary to implement new technologies, such as virtual prototyping, which can enable industry to have a rapid and more controlled decision making process. Virtual prototyping has come a long way in recent years, where current environments enable stereoscopic visuals, surround sound and ample interaction with the generated models. It is also important to evaluate how representative the developed virtual prototype is when compared to the real-world counterpart and the sense of presence reported by users of the virtual prototype. This paper describes the systematic procedure to develop a virtual prototype of Gazal-1 (i.e., the first car prototype designed by Saudi engineers in a semi-immersive virtual environment. The steps to develop a virtual prototype from CAD (computer-aided design models are explained in detail. Various issues involved in the different phases for the development of the virtual prototype are also discussed comprehensively. The paper further describes the results of the subjective assessment of a developed virtual prototype of a Saudi Arabian-designed automobile. User’s feedback is recorded using a presence questionnaire. Based on the user-based study, it is revealed that the virtual prototype is representative of the real Saudi Arabian car and offers a flexible environment to analyze design features when compared against its physical prototype. The capabilities of the virtual environment are validated with the application of the car prototype. Finally, vital requirements and directions for future research are also presented.

  6. A Method to Represent Heterogeneous Materials for Rapid Prototyping: The Matryoshka Approach.

    Science.gov (United States)

    Lei, Shuangyan; Frank, Matthew C; Anderson, Donald D; Brown, Thomas D

    The purpose of this paper is to present a new method for representing heterogeneous materials using nested STL shells, based, in particular, on the density distributions of human bones. Nested STL shells, called Matryoshka models, are described, based on their namesake Russian nesting dolls. In this approach, polygonal models, such as STL shells, are "stacked" inside one another to represent different material regions. The Matryoshka model addresses the challenge of representing different densities and different types of bone when reverse engineering from medical images. The Matryoshka model is generated via an iterative process of thresholding the Hounsfield Unit (HU) data using computed tomography (CT), thereby delineating regions of progressively increasing bone density. These nested shells can represent regions starting with the medullary (bone marrow) canal, up through and including the outer surface of the bone. The Matryoshka approach introduced can be used to generate accurate models of heterogeneous materials in an automated fashion, avoiding the challenge of hand-creating an assembly model for input to multi-material additive or subtractive manufacturing. This paper presents a new method for describing heterogeneous materials: in this case, the density distribution in a human bone. The authors show how the Matryoshka model can be used to plan harvesting locations for creating custom rapid allograft bone implants from donor bone. An implementation of a proposed harvesting method is demonstrated, followed by a case study using subtractive rapid prototyping to harvest a bone implant from a human tibia surrogate.

  7. Implementation of the Land, Atmosphere Near Real-Time Capability for EOS (LANCE)

    Science.gov (United States)

    Michael, Karen; Murphy, Kevin; Lowe, Dawn; Masuoka, Edward; Vollmer, Bruce; Tilmes, Curt; Teague, Michael; Ye, Gang; Maiden, Martha; Goodman, H. Michael; hide

    2010-01-01

    The past decade has seen a rapid increase in availability and usage of near real-time data from satellite sensors. Applications have demonstrated the utility of timely data in a number of areas ranging from numerical weather prediction and forecasting, to monitoring of natural hazards, disaster relief, agriculture and homeland security. As applications mature, the need to transition from prototypes to operational capabilities presents an opportunity to improve current near real-time systems and inform future capabilities. This paper presents NASA s effort to implement a near real-time capability for land and atmosphere data acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS), Atmospheric Infrared Sounder (AIRS), Advanced Microwave Scanning Radiometer - Earth Observing System (AMSR-E), Microwave Limb Sounder (MLS) and Ozone Monitoring Instrument (OMI) instruments on the Terra, Aqua, and Aura satellites. Index Terms- Real time systems, Satellite applications

  8. Rapid prototyping and evaluation of programmable SIMD SDR processors in LISA

    Science.gov (United States)

    Chen, Ting; Liu, Hengzhu; Zhang, Botao; Liu, Dongpei

    2013-03-01

    With the development of international wireless communication standards, there is an increase in computational requirement for baseband signal processors. Time-to-market pressure makes it impossible to completely redesign new processors for the evolving standards. Due to its high flexibility and low power, software defined radio (SDR) digital signal processors have been proposed as promising technology to replace traditional ASIC and FPGA fashions. In addition, there are large numbers of parallel data processed in computation-intensive functions, which fosters the development of single instruction multiple data (SIMD) architecture in SDR platform. So a new way must be found to prototype the SDR processors efficiently. In this paper we present a bit-and-cycle accurate model of programmable SIMD SDR processors in a machine description language LISA. LISA is a language for instruction set architecture which can gain rapid model at architectural level. In order to evaluate the availability of our proposed processor, three common baseband functions, FFT, FIR digital filter and matrix multiplication have been mapped on the SDR platform. Analytical results showed that the SDR processor achieved the maximum of 47.1% performance boost relative to the opponent processor.

  9. Product management of making large pieces through Rapid Prototyping PolyJet® technology

    Science.gov (United States)

    Belgiu, G.; Cărăuşu, C.; Şerban, D.; Turc, C. G.

    2017-08-01

    The rapid prototyping process has already become a classic manufacturing process for parts and assemblies, either polymeric or metal parts. Besides the well-known advantages and disadvantages of the process, the use of 3D printers has a great inconvenience: the overall dimensions of the parts are limited. Obviously, there is a possibility to purchase a larger (and more expensive) 3D printer, but there are always larger pieces to be manufactured. One solution to this problem is the splitting of parts into several components that can be manufactured. The component parts can then be assembled in a single piece by known methods such as welding, gluing, screwing, etc. This paper shows our experience in making large pieces on the Strarasys® Objet24 printer, pieces larger than the tray sizes. The results obtained are valid for any 3D printer using the PolyJet® process.

  10. OPAL jet chamber full scale prototype

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, H M; Hauschild, M; Hartmann, H; Hegerath, A; Boerner, H; Burckhart, H J; Dittmar, M; Hammarstroem, R; Heuer, R D; Mazzone, L

    1986-12-01

    The concept of a jet chamber for the central detector of OPAL has been tested with a full scale prototype. The design of this prototype, its mechanical and electrical structure and its support system for high voltage, gas, laser calibration and readout are described. Operating experience has been gathered since summer 1984. The chamber performance in terms of spatial resolution and particle identification capability is given.

  11. OPAL jet chamber full-scale prototype

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, H M; Hauschild, M; Hartmann, H; Hegerath, A; Boerner, H; Burckhart, H J; Dittmar, M; Hammarstroem, R; Heuer, R D; Mazzone, L

    1986-12-01

    The concept of a jet chamber for the central detector of OPAL was tested with a full scale prototype. The design of this prototype, its mechanical and electrical structure and its support system for high voltage, gas, laser calibration, and readout are described. Operating experience was gathered since summer 1984. The chamber performance in terms of spatial resolution and particle identification capability is given.

  12. Prototypical spent fuel rod consolidation equipment preliminary design report: Volume 1, Report

    International Nuclear Information System (INIS)

    1986-01-01

    This design report describes the NUS Preliminary Design of the Prototype Spent Nuclear Fuel Rod Consolidation Equipment for the Department of Energy. The sections of the report elaborate on each facet of the preliminary design. A concept summary is provided to assist the reader in rapidly understanding the complete design. The NUS Prototype Spent Fuel Rod Consolidation System is an automatically controlled system to consolidate a minimum of 750 MT (heavy metal)/year of US commercial nuclear reactor fuel, at 75% availability. The system is designed with replaceable components utilizing the latest state-of-the-art technology. This approach gives the system the flexibility to be developed without costly development programs, yet accept new technology as it evolves over the next ten years. Capability is also provided in the system design to accommodate a wide variety of fuel conditions and to recover from any situation which may arise

  13. Rapid Prototyping of the Central Safety System for Nuclear Risk in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Scibile, L. [ITER Organization, 13 - St. Paul lez Durance (France); Ambrosino, G.; De Tommasi, G.; Pironti, A. [Euratom-ENEA-CREATE, Universita di Napoli Federico II, Napoli (Italy)

    2009-07-01

    Full text of publication follows: In the current ITER Baseline design, the Central Safety System for Nuclear Risk (CSS-N) is the safety control system in charge to assure nuclear safety for the plant, personnel and environment. In particular it is envisaged that the CSS shall interface to the plant safety systems for nuclear risk and shall coordinate the individual protection provided by the intervention of these systems by the activation, where required, of additional protections. The design of such a system, together with its implementation, strongly depends on the requirements, particularly in terms of reliability. The CSS-N is a safety critical system, thus its validation and commissioning play a very important role, since the required level of reliability must be demonstrated. In such a scenario, where a new and non-conventional system has to be deployed, it is strongly recommended to use modeling and simulation tools since the early design phase. Indeed, the modeling tools will help in the definition of the system requirements, and they will be used to test and validate the control logic. Furthermore these tools can be used to rapid design the safety system and to carry out hardware-in-the-loop (HIL) simulations, which permit to assess the performance of the control hardware against a plant simulator. Both a control system prototype and a safety system oriented plant simulator have been developed to assess first the requirements and then the performance of the CSS-N. In particular the presented SW/HW framework permits to design and verify the CSS protection logics and to test and validate these logics by means of HIL simulations. This work introduces both the prototype and plant simulator architectures, together with the methodology adopted to design and implement these validation tools. (authors)

  14. Tangiplay: prototyping tangible electronic games

    OpenAIRE

    Boileau, Jason

    2010-01-01

    Tangible electronic games currently exist in research laboratories around the world but have yet to transition to the commercial sector. The development process of a tangible electronic game is one of the factors preventing progression, as it requires much time and money. Prototyping tools for tangible hardware and software development are becoming more available but are targeted to programmers and technically trained developers. Paper prototyping board and video games is a proven and rapid m...

  15. Sensitivity and Specificity of a Prototype Rapid Diagnostic Test for the Detection of Trypanosoma brucei gambiense Infection: A Multi-centric Prospective Study.

    Science.gov (United States)

    Bisser, Sylvie; Lumbala, Crispin; Nguertoum, Etienne; Kande, Victor; Flevaud, Laurence; Vatunga, Gedeao; Boelaert, Marleen; Büscher, Philippe; Josenando, Theophile; Bessell, Paul R; Biéler, Sylvain; Ndung'u, Joseph M

    2016-04-01

    A major challenge in the control of human African trypanosomiasis (HAT) is lack of reliable diagnostic tests that are rapid and easy to use in remote areas where the disease occurs. In Trypanosoma brucei gambiense HAT, the Card Agglutination Test for Trypanosomiasis (CATT) has been the reference screening test since 1978, usually on whole blood, but also in a 1/8 dilution (CATT 1/8) to enhance specificity. However, the CATT is not available in a single format, requires a cold chain for storage, and uses equipment that requires electricity. A solution to these challenges has been provided by rapid diagnostic tests (RDT), which have recently become available. A prototype immunochromatographic test, the SD BIOLINE HAT, based on two native trypanosomal antigens (VSG LiTat 1.3 and VSG LiTat 1.5) has been developed. We carried out a non-inferiority study comparing this prototype to the CATT 1/8 in field settings. The prototype SD BIOLINE HAT, the CATT Whole Blood and CATT 1/8 were systematically applied on fresh blood samples obtained from 14,818 subjects, who were prospectively enrolled through active and passive screening in clinical studies in three endemic countries of central Africa: Angola, the Democratic Republic of the Congo and the Central African Republic. One hundred and forty nine HAT cases were confirmed by parasitology. The sensitivity and specificity of the prototype SD BIOLINE HAT was 89.26% (95% confidence interval (CI) = 83.27-93.28) and 94.58% (95% CI = 94.20-94.94) respectively. The sensitivity and specificity of the CATT on whole blood were 93.96% (95% CI = 88.92-96.79) and 95.91% (95% CI = 95.58-96.22), and of the CATT 1/8 were 89.26% (95% CI = 83.27-93.28) and 98.88% (95% CI = 98.70-99.04) respectively. After further optimization, the prototype SD BIOLINE HAT could become an alternative to current screening methods in primary healthcare settings in remote, resource-limited regions where HAT typically occurs.

  16. Přehled pokročilých technik rapid prototyping a jejich využití ve slévárenství

    OpenAIRE

    Drda, Jan

    2012-01-01

    Tato práce se zabývá přehledem metod rapid prototyping a jejich možností uplatnění ve slévárenství. Je rozdělena do tří částí. V první je uvedeno, jakým postupem se obecně vytvoří model pomocí technologie rapid prototyping. Ve druhé části je vytvořen přehled metod, které se používají ve světě. Je rozdělena na tři menší části, které představují základní dělení metod. Jsou zde uvedeny základní principy metod, jejich výhody, nevýhody a použití. V poslední části je představeno shrnutí současného ...

  17. Rapid prototyping of biomimetic vascular phantoms for hyperspectral reflectance imaging

    Science.gov (United States)

    Ghassemi, Pejhman; Wang, Jianting; Melchiorri, Anthony J.; Ramella-Roman, Jessica C.; Mathews, Scott A.; Coburn, James C.; Sorg, Brian S.; Chen, Yu; Joshua Pfefer, T.

    2015-01-01

    Abstract. The emerging technique of rapid prototyping with three-dimensional (3-D) printers provides a simple yet revolutionary method for fabricating objects with arbitrary geometry. The use of 3-D printing for generating morphologically biomimetic tissue phantoms based on medical images represents a potentially major advance over existing phantom approaches. Toward the goal of image-defined phantoms, we converted a segmented fundus image of the human retina into a matrix format and edited it to achieve a geometry suitable for printing. Phantoms with vessel-simulating channels were then printed using a photoreactive resin providing biologically relevant turbidity, as determined by spectrophotometry. The morphology of printed vessels was validated by x-ray microcomputed tomography. Channels were filled with hemoglobin (Hb) solutions undergoing desaturation, and phantoms were imaged with a near-infrared hyperspectral reflectance imaging system. Additionally, a phantom was printed incorporating two disjoint vascular networks at different depths, each filled with Hb solutions at different saturation levels. Light propagation effects noted during these measurements—including the influence of vessel density and depth on Hb concentration and saturation estimates, and the effect of wavelength on vessel visualization depth—were evaluated. Overall, our findings indicated that 3-D-printed biomimetic phantoms hold significant potential as realistic and practical tools for elucidating light–tissue interactions and characterizing biophotonic system performance. PMID:26662064

  18. A Method to Represent Heterogeneous Materials for Rapid Prototyping: The Matryoshka Approach

    Science.gov (United States)

    Lei, Shuangyan; Frank, Matthew C.; Anderson, Donald D.; Brown, Thomas D.

    2015-01-01

    Purpose The purpose of this paper is to present a new method for representing heterogeneous materials using nested STL shells, based, in particular, on the density distributions of human bones. Design/methodology/approach Nested STL shells, called Matryoshka models, are described, based on their namesake Russian nesting dolls. In this approach, polygonal models, such as STL shells, are “stacked” inside one another to represent different material regions. The Matryoshka model addresses the challenge of representing different densities and different types of bone when reverse engineering from medical images. The Matryoshka model is generated via an iterative process of thresholding the Hounsfield Unit (HU) data using computed tomography (CT), thereby delineating regions of progressively increasing bone density. These nested shells can represent regions starting with the medullary (bone marrow) canal, up through and including the outer surface of the bone. Findings The Matryoshka approach introduced can be used to generate accurate models of heterogeneous materials in an automated fashion, avoiding the challenge of hand-creating an assembly model for input to multi-material additive or subtractive manufacturing. Originality/Value This paper presents a new method for describing heterogeneous materials: in this case, the density distribution in a human bone. The authors show how the Matryoshka model can be used to plan harvesting locations for creating custom rapid allograft bone implants from donor bone. An implementation of a proposed harvesting method is demonstrated, followed by a case study using subtractive rapid prototyping to harvest a bone implant from a human tibia surrogate. PMID:26120277

  19. Production of new 3D scaffolds for bone tissue regeneration by rapid prototyping.

    Science.gov (United States)

    Fradique, R; Correia, T R; Miguel, S P; de Sá, K D; Figueira, D R; Mendonça, A G; Correia, I J

    2016-04-01

    The incidence of bone disorders, whether due to trauma or pathology, has been trending upward with the aging of the worldwide population. The currently available treatments for bone injuries are rather limited, involving mainly bone grafts and implants. A particularly promising approach for bone regeneration uses rapid prototyping (RP) technologies to produce 3D scaffolds with highly controlled structure and orientation, based on computer-aided design models or medical data. Herein, tricalcium phosphate (TCP)/alginate scaffolds were produced using RP and subsequently their physicochemical, mechanical and biological properties were characterized. The results showed that 60/40 of TCP and alginate formulation was able to match the compression and present a similar Young modulus to that of trabecular bone while presenting an adequate biocompatibility. Moreover, the biomineralization ability, roughness and macro and microporosity of scaffolds allowed cell anchoring and proliferation at their surface, as well as cell migration to its interior, processes that are fundamental for osteointegration and bone regeneration.

  20. Cell-free synthetic biology for in vitro prototype engineering.

    Science.gov (United States)

    Moore, Simon J; MacDonald, James T; Freemont, Paul S

    2017-06-15

    Cell-free transcription-translation is an expanding field in synthetic biology as a rapid prototyping platform for blueprinting the design of synthetic biological devices. Exemplar efforts include translation of prototype designs into medical test kits for on-site identification of viruses (Zika and Ebola), while gene circuit cascades can be tested, debugged and re-designed within rapid turnover times. Coupled with mathematical modelling, this discipline lends itself towards the precision engineering of new synthetic life. The next stages of cell-free look set to unlock new microbial hosts that remain slow to engineer and unsuited to rapid iterative design cycles. It is hoped that the development of such systems will provide new tools to aid the transition from cell-free prototype designs to functioning synthetic genetic circuits and engineered natural product pathways in living cells. © 2017 The Author(s).

  1. Use of computer tomography and 3DP Rapid Prototyping technique in cranioplasty planning - analysis of accuracy of bone defect modeling

    International Nuclear Information System (INIS)

    Markowska, O.; Gardzinska, A.; Miechowicz, S.; Chrzan, R.; Urbanik, A.; Miechowicz, S.

    2009-01-01

    Background: The accuracy considerations of alignment of skull bone loss and artificial model of implant are presented. In standard surgical treatment the application of prefabricated alloplastic implants requires complicated procedures during surgery, especially additional geometry processing to provide better adjustment of implant. Rapid Prototyping can be used as an effective tool to generate complex 3D medical models and to improve and simplify surgical treatment planning. The operation time can also be significantly reduced. The aim of the study is adjustment accuracy analysis by measurements of fissure between the bone loss and implant. Material/Methods: The 3D numerical model was obtained from CT imaging with Siemens Sensation 10 CT scanner. The physical models were fabricated with 3DP Rapid Prototyping technology. The measurements were performed in determined points of the bone loss and implant borders. Results: Maximal width of fissure between bone loss and implant was 1.8 mm and minimal 0 mm. Average width was 0.714 mm, standard deviation 0.663 mm. Conclusions: Accuracy of 3DP technique is enough to create medical models in selected field of medicine. Models created using RP methods may be then used to produce implants of biocompatible material, for example by vacuum casting. Using of method suggested may allow shortening of presurgery and surgery time. (authors)

  2. Planar array stack design aided by rapid prototyping in development of air-breathing PEMFC

    Science.gov (United States)

    Chen, Chen-Yu; Lai, Wei-Hsiang; Weng, Biing-Jyh; Chuang, Huey-Jan; Hsieh, Ching-Yuan; Kung, Chien-Chih

    The polymer electrolyte membrane fuel cell (PEMFC) is one of the most important research topics in the new and clean energy area. The middle or high power PEMFCs can be applied to the transportation or the distributed power system. But for the small power application, it is needed to match the power requirement of the product generally. On the other hand, the direct methanol fuel cell (DMFC) is one of the most common type that researchers are interested in, but recently the miniature or the micro-PEMFCs attract more attention due to their advantages of high open circuit voltage and high power density. The objective of this study is to develop a new air-breathing planar array fuel cell stacked from 10 cells made by rapid prototyping technology which has potential for fast commercial design, low cost manufacturing, and even without converters/inverters for the system. In this paper, the main material of flow field plates is acrylonitrile-butadiene-styrene (ABS) which allows the fuel cell be mass-manufactured by plastic injection molding technology. The rapid prototyping technology is applied to construct the prototype and verify the practicability of the proposed stack design. A 10-cell air-breathing miniature PEMFC stack with a volume of 6 cm × 6 cm × 0.9 cm is developed and tested. Its segmented membrane electrode assembly (MEA) is designed with the active surface area of 1.3 cm × 1.3 cm in each individual MEA. The platinum loading at anode and cathode are 0.2 mg cm -2 and 0.4 mg cm -2, respectively. Results show that the peak power densities of the parallel connected and serial connected stack are 99 mW cm -2 at 0.425 V and 92 mW cm -2 at 4.25 V, respectively under the conditions of 70 °C relative saturated humidity (i.e., dew point temperature), ambient temperature and free convection air. Besides, the stack performance is increased under forced convection. If the cell surface air is blown by an electric fan, the peak power densities of parallel connected and

  3. Low-temperature deposition manufacturing: A novel and promising rapid prototyping technology for the fabrication of tissue-engineered scaffold.

    Science.gov (United States)

    Liu, Wei; Wang, Daming; Huang, Jianghong; Wei, You; Xiong, Jianyi; Zhu, Weimin; Duan, Li; Chen, Jielin; Sun, Rong; Wang, Daping

    2017-01-01

    Developed in recent years, low-temperature deposition manufacturing (LDM) represents one of the most promising rapid prototyping technologies. It is not only based on rapid deposition manufacturing process but also combined with phase separation process. Besides the controlled macropore size, tissue-engineered scaffold fabricated by LDM has inter-connected micropores in the deposited lines. More importantly, it is a green manufacturing process that involves non-heating liquefying of materials. It has been employed to fabricate tissue-engineered scaffolds for bone, cartilage, blood vessel and nerve tissue regenerations. It is a promising technology in the fabrication of tissue-engineered scaffold similar to ideal scaffold and the design of complex organs. In the current paper, this novel LDM technology is introduced, and its control parameters, biomedical applications and challenges are included and discussed as well. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Mechatronics Education: From Paper Design to Product Prototype Using LEGO NXT Parts

    Science.gov (United States)

    Lofaro, Daniel M.; Le, Tony Truong Giang; Oh, Paul

    The industrial design cycle starts with design then simulation, prototyping, and testing. When the tests do not match the design requirements the design process is started over again. It is important for students to experience this process before they leave their academic institution. The high cost of the prototype phase, due to CNC/Rapid Prototype machine costs, makes hands on study of this process expensive for students and the academic institutions. This document shows that the commercially available LEGO NXT Robot kit is a viable low cost surrogate to the expensive industrial CNC/Rapid Prototype portion of the industrial design cycle.

  5. Rapid Prototyping: State of the Art Review

    Science.gov (United States)

    2003-10-23

    Steel H13 Tool Steel CP Ti, Ti-6Al-4V Titanium Tungsten Copper Aluminum Nickel...The company’s LENS 750 and LENS 850 machines (both $440,000 to $640,000) are capable of producing parts in 16 stainless steel , H13 tool steel ...machining. 20 The Arcam EBM S12 model sells for $500,000 and is capable of processing two materials. One is H13 tool steel , while the other

  6. Characterization of rapidly-prototyped, battery-operated, argon-hydrogen microplasma on a hybrid chip for elemental analysis of microsamples by portable optical emission spectrometry

    Science.gov (United States)

    Weagant, Scott; Dulai, Gurjit; Li, Lu; Karanassios, Vassili

    2015-04-01

    A rapidly-prototyped, battery-operated, atmospheric-pressure, self-igniting Ar-H2 microplasma was interfaced to a portable fiber-optic spectrometer. The microplasma-spectrometer combination was used to document the spectral lines emitted when μL of dilute solutions of single element standards of Ag, Ba, Ca, Eu, Pd, Rb and Sr were first dried and then vaporized into the microplasma. A small-size, electrothermal vaporization system was used for microsample introduction. Identification of the prominent spectral lines for these elements is reported. It was found that the most prominent spectral line for Ba, Ca and Sr was different than that emitted from an inductively coupled plasma (ICP). In general, prominent spectral lines with low excitation energy were dominating, thus resulting in spectra simpler than those emitted from an ICP. Detection limits were between 45 and 180 pg (expressed in absolute amounts). When expressed in relative concentration units, they ranged between 15 and 60 μg/L (obtained using 3 μL diluted standards). Calibration curves were linear (on the average) for 1.5 orders-of-magnitude. Average precision was 15%. Analytical capability and utility was demonstrated using the determination of Ca and Mg in (medicinal) thermal spring water.

  7. AVSynDEx: A Rapid Prototyping Process Dedicated to the Implementation of Digital Image Processing Applications on Multi-DSP and FPGA Architectures

    Directory of Open Access Journals (Sweden)

    Fresse Virginie

    2002-01-01

    Full Text Available We present AVSynDEx (concatenation of AVS SynDEx, a rapid prototyping process aiming to the implementation of digital signal processing applications on mixed architectures (multi-DSP FPGA. This process is based on the use of widely available and efficient CAD tools established along the design process so that most of the implementation tasks become automatic. These tools and architectures are judiciously selected and integrated during the implementation process to help a signal processing specialist without relevant hardware experience. We have automated the translation between the different levels of the process to increase and secure it. One main advantage is that only a signal processing designer is needed, all the other specialized manual tasks being transparent in this prototyping methodology, hereby reducing the implementation time.

  8. Mobile Prototyping Platforms for Remote Engineering Applications

    Directory of Open Access Journals (Sweden)

    Karsten Henke

    2009-08-01

    Full Text Available This paper describes a low-cost mobile communication platform as a universal rapid-prototyping system, which is based on the Quadrocopter concept. At the Integrated Hardware and Software Systems Group at the Ilmenau University of Technology these mobile platforms are used to motivate bachelor and master students to study Computer Engineering sciences. This could be done by increasing their interest in technical issues, using this platform as integral part of a new ad-hoc lab to demonstrate different aspects in the area of Mobile Communication as well as universal rapid prototyping nodes to investigate different mechanisms for self-organized mobile communication systems within the International Graduate School on Mobile Communications. Beside the three fields of application, the paper describes the current architecture concept of the mobile prototyping platform as well as the chosen control mechanism and the assigned sensor systems to fulfill all the required tasks.

  9. AGS booster prototype magnets

    International Nuclear Information System (INIS)

    Danby, G.; Jackson, J.; Lee, Y.Y.; Phillips, R.; Brodowski, J.; Jablonski, E.; Keohane, G.; McDowell, B.; Rodger, E.

    1987-01-01

    Prototype magnets have been designed and constructed for two half cells of the AGS Booster. The lattice requires 2.4m long dipoles, each curved by 10 0 . The multi-use Booster injector requires several very different standard magnet cycles, capable of instantaneous interchange using computer control from dc up to 10 Hz

  10. A system for rapid prototyping of hearts with congenital malformations based on the medical imaging interaction toolkit (MITK)

    Science.gov (United States)

    Wolf, Ivo; Böttger, Thomas; Rietdorf, Urte; Maleike, Daniel; Greil, Gerald; Sieverding, Ludger; Miller, Stephan; Mottl-Link, Sibylle; Meinzer, Hans-Peter

    2006-03-01

    Precise knowledge of the individual cardiac anatomy is essential for diagnosis and treatment of congenital heart disease. Complex malformations of the heart can best be comprehended not from images but from anatomic specimens. Physical models can be created from data using rapid prototyping techniques, e.g., lasersintering or 3D-printing. We have developed a system for obtaining data that show the relevant cardiac anatomy from high-resolution CT/MR images and are suitable for rapid prototyping. The challenge is to preserve all relevant details unaltered in the produced models. The main anatomical structures of interest are the four heart cavities (atria, ventricles), the valves and the septum separating the cavities, and the great vessels. These can be shown either by reproducing the morphology itself or by producing a model of the blood-pool, thus creating a negative of the morphology. Algorithmically the key issue is segmentation. Practically, possibilities allowing the cardiologist or cardiac surgeon to interactively check and correct the segmentation are even more important due to the complex, irregular anatomy and imaging artefacts. The paper presents the algorithmic and interactive processing steps implemented in the system, which is based on the open-source Medical Imaging Interaction Toolkit (MITK, www.mitk.org). It is shown how the principles used in MITK enable to assemble the system from modules (functionalities) developed independently from each other. The system allows to produce models of the heart (and other anatomic structures) of individual patients as well as to reproduce unique specimens from pathology collections for teaching purposes.

  11. A platform for rapid prototyping of synthetic gene networks in mammalian cells

    Science.gov (United States)

    Duportet, Xavier; Wroblewska, Liliana; Guye, Patrick; Li, Yinqing; Eyquem, Justin; Rieders, Julianne; Rimchala, Tharathorn; Batt, Gregory; Weiss, Ron

    2014-01-01

    Mammalian synthetic biology may provide novel therapeutic strategies, help decipher new paths for drug discovery and facilitate synthesis of valuable molecules. Yet, our capacity to genetically program cells is currently hampered by the lack of efficient approaches to streamline the design, construction and screening of synthetic gene networks. To address this problem, here we present a framework for modular and combinatorial assembly of functional (multi)gene expression vectors and their efficient and specific targeted integration into a well-defined chromosomal context in mammalian cells. We demonstrate the potential of this framework by assembling and integrating different functional mammalian regulatory networks including the largest gene circuit built and chromosomally integrated to date (6 transcription units, 27kb) encoding an inducible memory device. Using a library of 18 different circuits as a proof of concept, we also demonstrate that our method enables one-pot/single-flask chromosomal integration and screening of circuit libraries. This rapid and powerful prototyping platform is well suited for comparative studies of genetic regulatory elements, genes and multi-gene circuits as well as facile development of libraries of isogenic engineered cell lines. PMID:25378321

  12. AGS Booster prototype magnets

    Energy Technology Data Exchange (ETDEWEB)

    Danby, G.; Jackson, J.; Lee, Y.Y.; Phillips, R.; Brodowski, J.; Jablonski, E.; Keohane, G.; McDowell, B.; Rodger, E.

    1987-03-19

    Prototype magnets have been designed and constructed for two half cells of the AGS Booster. The lattice requires 2.4m long dipoles, each curved by 10/sup 0/. The multi-use Booster injector requires several very different standard magnet cycles, capable of instantaneous interchange using computer control from dc up to 10 Hz.

  13. Interactive visual steering--rapid visual prototyping of a common rail injection system.

    Science.gov (United States)

    Matković, Kresimir; Gracanin, Denis; Jelović, Mario; Hauser, Helwig

    2008-01-01

    Interactive steering with visualization has been a common goal of the visualization research community for twenty years, but it is rarely ever realized in practice. In this paper we describe a successful realization of a tightly coupled steering loop, integrating new simulation technology and interactive visual analysis in a prototyping environment for automotive industry system design. Due to increasing pressure on car manufacturers to meet new emission regulations, to improve efficiency, and to reduce noise, both simulation and visualization are pushed to their limits. Automotive system components, such as the powertrain system or the injection system have an increasing number of parameters, and new design approaches are required. It is no longer possible to optimize such a system solely based on experience or forward optimization. By coupling interactive visualization with the simulation back-end (computational steering), it is now possible to quickly prototype a new system, starting from a non-optimized initial prototype and the corresponding simulation model. The prototyping continues through the refinement of the simulation model, of the simulation parameters and through trial-and-error attempts to an optimized solution. The ability to early see the first results from a multidimensional simulation space--thousands of simulations are run for a multidimensional variety of input parameters--and to quickly go back into the simulation and request more runs in particular parameter regions of interest significantly improves the prototyping process and provides a deeper understanding of the system behavior. The excellent results which we achieved for the common rail injection system strongly suggest that our approach has a great potential of being generalized to other, similar scenarios.

  14. A Prototype HTML Training System for Graphic Communication Majors

    Science.gov (United States)

    Runquist, Roger L.

    2010-01-01

    This design research demonstrates a prototype content management system capable of training graphic communication students in the creation of basic HTML web pages. The prototype serve as a method of helping students learn basic HTML structure and commands earlier in their academic careers. Exposure to the concepts of web page creation early in…

  15. Processing of pure Ti by rapid prototyping based on laser cladding

    Science.gov (United States)

    Arias-González, F.; del Val, J.; Comesaña, R.; Lusquiños, F.; Quintero, F.; Riveiro, A.; Boutinguiza, M.; Pou, J.

    2013-11-01

    Rapid prototyping based on laser cladding is an additive manufacturing (AM) process based on the overlapping of cladding tracks to produce functional components. Powder or wire are fed into a melting pool created using laser radiation as a heat source and the relative movement between the beam and the work piece makes possible to generate pieces layer-by-layer. This technique can be applied for any material which can be melted and the components can be manufactured directly according to a computer aided design (CAD) model. Additive manufacturing is particularly interesting to produce titanium components because, in this case, the loss of material produced by subtractive manufacturing methods is highly costly. Moreover, titanium and its alloys are widely used in biomedical, aircraft, chemical and marine industries due to their biocompatibility, excellent corrosion resistance and superior strength-to-weight ratio. In this research work, a near-infrared laser delivering a maximum power of 500W is used to produce pure titanium thin parts. Dimensions and surface morphology are characterized using Optical Microscopy (OM) and Scanning Electron Microscopy (SEM), the hardness by nanoindentation and the composition by X-Ray Diffraction (XRD) and Energy Dispersive X-Ray Spectroscopy (EDS). The aim of this work is to establish the conditions under which satisfactory properties are obtained and to understand the relationship between microstructure/properties and deposition parameters.

  16. Optimization of FIB milling for rapid NEMS prototyping

    DEFF Research Database (Denmark)

    Malm, Bjarke; Petersen, Dirch Hjorth; Lei, Anders

    2011-01-01

    We demonstrate an optimized milling technique to focused ion beam (FIB) milling in template silicon membranes for fast prototyping of nanoelectromechanical systems (NEMS). Using a single-pass milling strategy the highly topology dependent sputtering rate is boosted and shorter milling time...... is achieved. Drift independence is obtained for small critical features using a radial scan strategy, and a back scan routine ensures minimal line width deviation removing redeposited material. Milling a design similar to a nano four-point probe with a pitch down to 400nm we display what optimized FIB milling...

  17. PRODUCTION OF PROTOTYPE PARTS USING DIRECT METAL LASER SINTERING TECHNOLOGY

    Directory of Open Access Journals (Sweden)

    Josef Sedlak

    2015-08-01

    Full Text Available Unconventional methods of modern materials preparation include additive technologies which involve the sintering of powders of different chemical composition, granularity, physical, chemical and other utility properties. The technology called Rapid Prototyping, which uses different technological principles of producing components, belongs to this type of material preparation. The Rapid Prototyping technology facilities use photopolymers, thermoplastics, specially treated paper or metal powders. The advantage is the direct production of metal parts from input data and the fact that there is no need for the production of special tools (moulds, press tools, etc.. Unused powder from sintering technologies is re-used for production 98% of the time, which means that the process is economical, as well as ecological.The present paper discusses the technology of Direct Metal Laser Sintering (DMLS, which falls into the group of additive technologies of Rapid Prototyping (RP. The major objective is a detailed description of DMLS, pointing out the benefits it offers and its application in practice. The practical part describes the production and provides an economic comparison of several prototype parts that were designed for testing in the automotive industry.

  18. Risk D and D Rapid Prototype: Scenario Documentation and Analysis Tool

    International Nuclear Information System (INIS)

    Unwin, Stephen D.; Seiple, Timothy E.

    2009-01-01

    Report describes process and methodology associated with a rapid prototype tool for integrating project risk analysis and health and safety risk analysis for decontamination and decommissioning projects. The objective of the Decontamination and Decommissioning (D and D) Risk Management Evaluation and Work Sequencing Standardization Project under DOE EM-23 is to recommend or develop practical risk-management tools for decommissioning of nuclear facilities. PNNL has responsibility under this project for recommending or developing computer-based tools that facilitate the evaluation of risks in order to optimize the sequencing of D and D work. PNNL's approach is to adapt, augment, and integrate existing resources rather than to develop a new suite of tools. Methods for the evaluation of H and S risks associated with work in potentially hazardous environments are well-established. Several approaches exist which, collectively, are referred to as process hazard analysis (PHA). A PHA generally involves the systematic identification of accidents, exposures, and other adverse events associated with a given process or work flow. This identification process is usually achieved in a brainstorming environment or by other means of eliciting informed opinion. The likelihoods of adverse events (scenarios) and their associated consequence severities are estimated against pre-defined scales, based on which risk indices are then calculated. A similar process is encoded in various project risk software products that facilitate the quantification of schedule and cost risks associated with adverse scenarios. However, risk models do not generally capture both project risk and H and S risk. The intent of the project reported here is to produce a tool that facilitates the elicitation, characterization, and documentation of both project risk and H and S risk based on defined sequences of D and D activities. By considering alternative D and D sequences, comparison of the predicted risks can

  19. Fabrication and characterization of a rapid prototyped tissue engineering scaffold with embedded multicomponent matrix for controlled drug release

    DEFF Research Database (Denmark)

    Chen, Muwan; Le, Dang Q S; Hein, San

    2012-01-01

    Bone tissue engineering implants with sustained local drug delivery provide an opportunity for better postoperative care for bone tumor patients because these implants offer sustained drug release at the tumor site and reduce systemic side effects. A rapid prototyped macroporous polycaprolactone......, this scaffold can fulfill the requirements for both bone tissue engineering and local sustained release of an anticancer drug in vitro. These results suggest that the scaffold can be used clinically in reconstructive surgery after bone tumor resection. Moreover, by changing the composition and amount...... of individual components, the scaffold can find application in other tissue engineering areas that need local sustained release of drug....

  20. Rapid BeagleBoard prototyping with MATLAB and Simulink

    CERN Document Server

    Qin, Fei

    2013-01-01

    This book is a fast-paced guide with practical, hands-on recipes which will show you how to prototype Beagleboard-based audio/video applications using Matlab/Simlink and Sourcery Codebench on a Windows host.Beagleboard Embedded Projects is great for students and academic researchers who have practical ideas and who want to build a proof-of-concept system on an embedded hardware platform quickly and efficiently. It is also useful for product design engineers who want to ratify their applications and reduce the time-to-market. It is assumed that you are familiar with Matlab/Simulink and have som

  1. Rapid prototyping of reflectors for vehicle lighting using laser activated remote phosphor

    Science.gov (United States)

    Lachmayer, Roland; Kloppenburg, Gerolf; Wolf, Alexander

    2015-03-01

    Bright white light sources are of significant importance for automotive front lighting systems. Today's upper class vehicles mainly use HID or LED as light source. As a further step in this development laser diode based systems offer high luminance, efficiency and allow the realization of new styling concepts and new dynamic lighting functions. These white laser diode systems can either be realized by mixing different spectral sources or by combining diodes with specific phosphors. Based on the approach of generating light using a laser and remote phosphor, lighting modules are manufactured. Four blue laser diodes (450 nm) are used to activate a phosphor coating and thus to achieve white light. A segmented paraboloid reflector generates the desired light distribution for an additional car headlamp. We use high speed milling and selective laser melting to build the reflector system for this lighting module. We compare the spectral reflection grade of these materials. Furthermore the generated modules are analyzed regarding their efficiency and light distribution. The use of Rapid Prototyping technologies allows an early validation of the chosen concept and is supposed to reduce cost and time in the product development process significantly. Therefor we discuss costs and times of the applied manufacturing technologies.

  2. Low Cost Rapid Response Spacecraft, (LCRRS): A Research Project in Low Cost Spacecraft Design and Fabrication in a Rapid Prototyping Environment

    Science.gov (United States)

    Spremo, Stevan; Bregman, Jesse; Dallara, Christopher D.; Ghassemieh, Shakib M.; Hanratty, James; Jackson, Evan; Kitts, Christopher; Klupar, Pete; Lindsay, Michael; Ignacio, Mas; hide

    2009-01-01

    The Low Cost Rapid Response Spacecraft (LCRRS) is an ongoing research development project at NASA Ames Research Center (ARC), Moffett Field, California. The prototype spacecraft, called Cost Optimized Test for Spacecraft Avionics and Technologies (COTSAT) is the first of what could potentially be a series of rapidly produced low-cost satellites. COTSAT has a target launch date of March 2009 on a SpaceX Falcon 9 launch vehicle. The LCRRS research system design incorporates use of COTS (Commercial Off The Shelf), MOTS (Modified Off The Shelf), and GOTS (Government Off The Shelf) hardware for a remote sensing satellite. The design concept was baselined to support a 0.5 meter Ritchey-Chretien telescope payload. This telescope and camera system is expected to achieve 1.5 meter/pixel resolution. The COTSAT team is investigating the possibility of building a fully functional spacecraft for $500,000 parts and $2,000,000 labor. Cost is dramatically reduced by using a sealed container, housing the bus and payload subsystems. Some electrical and RF designs were improved/upgraded from GeneSat-1 heritage systems. The project began in January 2007 and has yielded two functional test platforms. It is expected that a flight-qualified unit will be finished in December 2008. Flight quality controls are in place on the parts and materials used in this development with the aim of using them to finish a proto-flight satellite. For LEO missions the team is targeting a mission class requiring a minimum of six months lifetime or more. The system architecture incorporates several design features required by high reliability missions. This allows for a true skunk works environment to rapidly progress toward a flight design. Engineering and fabrication is primarily done in-house at NASA Ames with flight certifications on materials. The team currently employs seven Full Time Equivalent employees. The success of COTSATs small team in this effort can be attributed to highly cross trained

  3. Comparative use of the computer-aided angiography and rapid prototyping technology versus conventional imaging in the management of the Tile C pelvic fractures.

    Science.gov (United States)

    Li, Baofeng; Chen, Bei; Zhang, Ying; Wang, Xinyu; Wang, Fei; Xia, Hong; Yin, Qingshui

    2016-01-01

    Computed tomography (CT) scan with three-dimensional (3D) reconstruction has been used to evaluate complex fractures in pre-operative planning. In this study, rapid prototyping of a life-size model based on 3D reconstructions including bone and vessel was applied to evaluate the feasibility and prospect of these new technologies in surgical therapy of Tile C pelvic fractures by observing intra- and perioperative outcomes. The authors conducted a retrospective study on a group of 157 consecutive patients with Tile C pelvic fractures. Seventy-six patients were treated with conventional pre-operative preparation (A group) and 81 patients were treated with the help of computer-aided angiography and rapid prototyping technology (B group). Assessment of the two groups considered the following perioperative parameters: length of surgical procedure, intra-operative complications, intra- and postoperative blood loss, postoperative pain, postoperative nausea and vomiting (PONV), length of stay, and type of discharge. The two groups were homogeneous when compared in relation to mean age, sex, body weight, injury severity score, associated injuries and pelvic fracture severity score. Group B was performed in less time (105 ± 19 minutes vs. 122 ± 23 minutes) and blood loss (31.0 ± 8.2 g/L vs. 36.2 ± 7.4 g/L) compared with group A. Patients in group B experienced less pain (2.5 ± 2.3 NRS score vs. 2.8 ± 2.0 NRS score), and PONV affected only 8 % versus 10 % of cases. Times to discharge were shorter (7.8 ± 2.0 days vs. 10.2 ± 3.1 days) in group B, and most of patients were discharged to home. In our study, patients of Tile C pelvic fractures treated with computer-aided angiography and rapid prototyping technology had a better perioperative outcome than patients treated with conventional pre-operative preparation. Further studies are necessary to investigate the advantages in terms of clinical results in the short and long run.

  4. Flight Telerobotic Servicer prototype simulator

    Science.gov (United States)

    Schein, Rob; Krauze, Linda; Hartley, Craig; Dickenson, Alan; Lavecchia, Tom; Working, Bob

    A prototype simulator for the Flight Telerobotic Servicer (FTS) system is described for use in the design development of the FTS, emphasizing the hand controller and user interface. The simulator utilizes a graphics workstation based on rapid prototyping tools for systems analyses of the use of the user interface and the hand controller. Kinematic modeling, manipulator-control algorithms, and communications programs are contained in the software for the simulator. The hardwired FTS panels and operator interface for use on the STS Orbiter are represented graphically, and the simulated controls function as the final FTS system configuration does. The robotic arm moves based on the user hand-controller interface, and the joint angles and other data are given on the prototype of the user interface. This graphics simulation tool provides the means for familiarizing crewmembers with the FTS system operation, displays, and controls.

  5. Rapid Prototyping of a Cyclic Olefin Copolymer Microfluidic Device for Automated Oocyte Culturing.

    Science.gov (United States)

    Berenguel-Alonso, Miguel; Sabés-Alsina, Maria; Morató, Roser; Ymbern, Oriol; Rodríguez-Vázquez, Laura; Talló-Parra, Oriol; Alonso-Chamarro, Julián; Puyol, Mar; López-Béjar, Manel

    2017-10-01

    Assisted reproductive technology (ART) can benefit from the features of microfluidic technologies, such as the automation of time-consuming labor-intensive procedures, the possibility to mimic in vivo environments, and the miniaturization of the required equipment. To date, most of the proposed approaches are based on polydimethylsiloxane (PDMS) as platform substrate material due to its widespread use in academia, despite certain disadvantages, such as the elevated cost of mass production. Herein, we present a rapid fabrication process for a cyclic olefin copolymer (COC) monolithic microfluidic device combining hot embossing-using a low-temperature cofired ceramic (LTCC) master-and micromilling. The microfluidic device was suitable for trapping and maturation of bovine oocytes, which were further studied to determine their ability to be fertilized. Furthermore, another COC microfluidic device was fabricated to store sperm and assess its quality parameters over time. The study herein presented demonstrates a good biocompatibility of the COC when working with gametes, and it exhibits certain advantages, such as the nonabsorption of small molecules, gas impermeability, and low fabrication costs, all at the prototyping and mass production scale, thus taking a step further toward fully automated microfluidic devices in ART.

  6. Impact of Personnel Capabilities on Organizational Innovation Capability

    DEFF Research Database (Denmark)

    Nielsen, Susanne Balslev; Momeni, Mostafa

    2016-01-01

    in this rapidly changing world. This research focuses on definition of the personnel aspect of innovation capability, and proposes a conceptual model based on the scientific articles of academic literature on organisations innovation capability. This paper includes an expert based validation in three rounds...... of the Delphi method. And for the purpose of a better appreciation of the relationship dominating the factors of the model, it has distributed the questionnaire to Iranian companies in the Food industry. This research proposed a direct relationship between Innovation Capability and the Personnel Capability...

  7. Rapid prototyping of a complex model for the manufacture of plaster molds for slip casting ceramic

    Directory of Open Access Journals (Sweden)

    D. P. C. Velazco

    2014-12-01

    Full Text Available Computer assisted designing (CAD is well known for several decades and employed for ceramic manufacturing almost since the beginning, but usually employed in the first part of the projectual ideation processes, neither in the prototyping nor in the manufacturing stages. The rapid prototyping machines, also known as 3D printers, have the capacity to produce in a few hours real pieces using plastic materials of high resistance, with great precision and similarity with respect to the original, based on unprecedented digital models produced by means of modeling with specific design software or from the digitalization of existing parts using the so-called 3D scanners. The main objective of the work is to develop the methodology used in the entire process of building a part in ceramics from the interrelationship between traditional techniques and new technologies for the manufacture of prototypes. And to take advantage of the benefits that allow us this new reproduction technology. The experience was based on the generation of a complex piece, in digital format, which served as the model. A regular 15 cm icosahedron presented features complex enough not to advise the production of the model by means of the traditional techniques of ceramics (manual or mechanical. From this digital model, a plaster mold was made in the traditional way in order to slip cast clay based slurries, freely dried in air and fired and glazed in the traditional way. This experience has shown the working hypothesis and opens up the possibility of new lines of work to academic and technological levels that will be explored in the near future. This technology provides a wide range of options to address the formal aspect of a part to be performed for the field of design, architecture, industrial design, the traditional pottery, ceramic art, etc., which allow you to amplify the formal possibilities, save time and therefore costs when drafting the necessary and appropriate matrixes

  8. Lab on a Biomembrane: Rapid prototyping and manipulation of 2D fluidic lipid bilayers circuits

    Science.gov (United States)

    Ainla, Alar; Gözen, Irep; Hakonen, Bodil; Jesorka, Aldo

    2013-01-01

    Lipid bilayer membranes are among the most ubiquitous structures in the living world, with intricate structural features and a multitude of biological functions. It is attractive to recreate these structures in the laboratory, as this allows mimicking and studying the properties of biomembranes and their constituents, and to specifically exploit the intrinsic two-dimensional fluidity. Even though diverse strategies for membrane fabrication have been reported, the development of related applications and technologies has been hindered by the unavailability of both versatile and simple methods. Here we report a rapid prototyping technology for two-dimensional fluidic devices, based on in-situ generated circuits of phospholipid films. In this “lab on a molecularly thin membrane”, various chemical and physical operations, such as writing, erasing, functionalization, and molecular transport, can be applied to user-defined regions of a membrane circuit. This concept is an enabling technology for research on molecular membranes and their technological use. PMID:24067786

  9. Mr.CAS-A minimalistic (pure) Ruby CAS for fast prototyping and code generation

    Science.gov (United States)

    Ragni, Matteo

    There are Computer Algebra System (CAS) systems on the market with complete solutions for manipulation of analytical models. But exporting a model that implements specific algorithms on specific platforms, for target languages or for particular numerical library, is often a rigid procedure that requires manual post-processing. This work presents a Ruby library that exposes core CAS capabilities, i.e. simplification, substitution, evaluation, etc. The library aims at programmers that need to rapidly prototype and generate numerical code for different target languages, while keeping separated mathematical expression from the code generation rules, where best practices for numerical conditioning are implemented. The library is written in pure Ruby language and is compatible with most Ruby interpreters.

  10. Mr.CAS—A minimalistic (pure Ruby CAS for fast prototyping and code generation

    Directory of Open Access Journals (Sweden)

    Matteo Ragni

    2017-01-01

    Full Text Available There are Computer Algebra System (CAS systems on the market with complete solutions for manipulation of analytical models. But exporting a model that implements specific algorithms on specific platforms, for target languages or for particular numerical library, is often a rigid procedure that requires manual post-processing. This work presents a Ruby library that exposes core CAS capabilities, i.e. simplification, substitution, evaluation, etc. The library aims at programmers that need to rapidly prototype and generate numerical code for different target languages, while keeping separated mathematical expression from the code generation rules, where best practices for numerical conditioning are implemented. The library is written in pure Ruby language and is compatible with most Ruby interpreters.

  11. Axure RP 6 Prototyping Essentials

    CERN Document Server

    Schwartz, Ezra

    2012-01-01

    Axure RP 6 Prototyping Essentials is a detailed, practical primer on the leading rapid prototyping tool. Short on jargon and high on concepts, real-life scenarios and step-by-step guidance through hands-on examples, this book will show you how to integrate Axure into your UX workflow. This book is written for UX practitioners, business analysts, product managers, and anyone else who is involved in UX projects. The book assumes that you have no or very little familiarity with Axure. It will help you if you are evaluating the tool for an upcoming project or are required to quickly get up to spee

  12. “In vitro” Implantation Technique Based on 3D Printed Prosthetic Prototypes

    Science.gov (United States)

    Tarnita, D.; Boborelu, C.; Geonea, I.; Malciu, R.; Grigorie, L.; Tarnita, D. N.

    2018-06-01

    In this paper, Rapid Prototyping ZCorp 310 system, based on high-performance composite powder and on resin-high strength infiltration system and three-dimensional printing as a manufacturing method are used to obtain physical prototypes of orthopaedic implants and prototypes of complex functional prosthetic systems directly from the 3D CAD data. These prototypes are useful for in vitro experimental tests and measurements to optimize and obtain final physical prototypes. Using a new elbow prosthesis model prototype obtained by 3D printing, the surgical technique of implantation is established. Surgical implantation was performed on male corpse elbow joint.

  13. Bone regeneration of critical calvarial defect in goat model by PLGA/TCP/rhBMP-2 scaffolds prepared by low-temperature rapid-prototyping technology.

    Science.gov (United States)

    Yu, D; Li, Q; Mu, X; Chang, T; Xiong, Z

    2008-10-01

    Active artificial bone composed of poly lactide-co-glycolide (PLGA)/ tricalcium phosphate (TCP) was prefabricated using low-temperature rapid-prototyping technology so that the process of osteogenesis could be observed in it. PLGA and TCP were the primary materials, they were molded at low temperature, then recombinant human bone morphogenetic protein-2 (rhBMP-2) was added to form an active artificial bone. Goats with standard cranial defects were randomly divided into experimental (implants with rhBMP-2 added) and control (implants without rhBMP-2) groups, and osteogenesis was observed and evaluated by imaging and biomechanical and histological examinations. The PLGA-TCP artificial bone scaffold (90% porosity) had large and small pores of approximately 360microm and 3-5microm diameter. Preliminary and complete repair of the cranial defect in the goats occurred 12 and 24 weeks after surgery, respectively. The three-point bending strength of the repaired defects attained that of the normal cranium. In conclusion, low-temperature rapid-prototyping technology can preserve the biological activity of this scaffold material. The scaffold has a good three-dimensional structure and it becomes an active artificial bone after loading with rhBMP-2 with a modest degradation rate and excellent osteogenesis in the goat.

  14. Expedited Systems Engineering for Rapid Capability and Urgent Needs

    Science.gov (United States)

    2012-12-31

    these areas. Different techniques for specification of software requirements (SysML), simulation models (Arena) and enterprise architecture ( BPMN ...were compared and the different concepts of each language were related to each other using DoDAF 2.0 as a framework. A prototype converter between BPMN ...2.0 XML and Arena was developed that allowed users to reuse BPMN models for event simulation. Motivation: Requirements management for software

  15. Application of Rapid Prototyping Pelvic Model for Patients with DDH to Facilitate Arthroplasty Planning: A Pilot Study.

    Science.gov (United States)

    Xu, Jie; Li, Deng; Ma, Ruo-fan; Barden, Bertram; Ding, Yue

    2015-11-01

    Total hip arthroplasty (THA) is challenging in cases of osteoarthritis secondary to developmental dysplasia of the hip (DDH). Acetabular deficiency makes the positioning of the acetabular component difficult. Computer tomography based, patient-individual three dimensional (3-D) rapid prototype technology (RPT)-models were used to plan the placement of acetabular cup so that a surgeon was able to identify pelvic structures, assess the ideal extent of reaming and determine the size of cup after a reconstructive procedure. Intraclass correlation coefficients (ICCs) were used to analyze the agreement between the sizes of chosen components on the basis of preoperative planning and the actual sizes used in the operation. The use of the 3-D RPT-model facilitates the surgical procedures due to better planning and improved orientation. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Evaluation of a prototype infrasound system

    International Nuclear Information System (INIS)

    Whitaker, R.; Sandoval, T.; Breding, D.; Kromer, D.

    1997-01-01

    Under Department of Energy sponsorship, Sandia National Laboratories and Los Alamos National Laboratory cooperated to develop a prototype infrasonic array, with associated documentation, that could be used as part of the International Monitoring System. The United States Government or foreign countries could procure commercially available systems based on this prototype to fulfill their Comprehensive Test Ban Treaty (CTBT) obligations. The prototype is a four-element array in a triangular layout as recommended in CD/NTB/WP.224 with an element at each corner and one in the center. The prototype test configuration utilize an array spacing of 1 km. The prototype infrasound system has the following objectives: (1) Provide a prototype that reliably acquires and transmits near real-time infrasonic data to facilitate the rapid location and identification of atmospheric events. (2) Provide documentation that could be used by the United States and foreign countries to procure infrasound systems commercially to fulfill their CTBT responsibilities. Infrasonic monitoring is an effective, low cost technology for detecting atmospheric explosions. The low frequency components of explosion signals propagate to long ranges (few thousand kilometers) where they can be detected with an array of sensors. Los Alamos National Laboratory's expertise in infrasound systems and phenomenology when combined with Sandia's expertise in providing verification quality system for treaty monitoring make an excellent team to provide the prototype infrasound sensor system. By September 1997, the prototype infrasound system will have been procured, integrated, evaluated and documented. Final documentation will include a system requirements document, an evaluation report and a hardware design document. The hardware design document will describe the various hardware components used in the infrasound prototype and their interrelationships

  17. Digital Microdroplet Ejection Technology-Based Heterogeneous Objects Prototyping

    Science.gov (United States)

    Yang, Jiquan; Feng, Chunmei; Yang, Jianfei; Zhu, Liya; Guo, Aiqing

    2016-01-01

    An integrate fabrication framework is presented to build heterogeneous objects (HEO) using digital microdroplets injecting technology and rapid prototyping. The heterogeneous materials part design and manufacturing method in structure and material was used to change the traditional process. The net node method was used for digital modeling that can configure multimaterials in time. The relationship of material, color, and jetting nozzle was built. The main important contributions are to combine the structure, material, and visualization in one process and give the digital model for manufacture. From the given model, it is concluded that the method is effective for HEO. Using microdroplet rapid prototyping and the model given in the paper HEO could be gotten basically. The model could be used in 3D biomanufacturing. PMID:26981110

  18. Digital Microdroplet Ejection Technology-Based Heterogeneous Objects Prototyping

    Directory of Open Access Journals (Sweden)

    Na Li

    2016-01-01

    Full Text Available An integrate fabrication framework is presented to build heterogeneous objects (HEO using digital microdroplets injecting technology and rapid prototyping. The heterogeneous materials part design and manufacturing method in structure and material was used to change the traditional process. The net node method was used for digital modeling that can configure multimaterials in time. The relationship of material, color, and jetting nozzle was built. The main important contributions are to combine the structure, material, and visualization in one process and give the digital model for manufacture. From the given model, it is concluded that the method is effective for HEO. Using microdroplet rapid prototyping and the model given in the paper HEO could be gotten basically. The model could be used in 3D biomanufacturing.

  19. Digital Microdroplet Ejection Technology-Based Heterogeneous Objects Prototyping.

    Science.gov (United States)

    Li, Na; Yang, Jiquan; Feng, Chunmei; Yang, Jianfei; Zhu, Liya; Guo, Aiqing

    2016-01-01

    An integrate fabrication framework is presented to build heterogeneous objects (HEO) using digital microdroplets injecting technology and rapid prototyping. The heterogeneous materials part design and manufacturing method in structure and material was used to change the traditional process. The net node method was used for digital modeling that can configure multimaterials in time. The relationship of material, color, and jetting nozzle was built. The main important contributions are to combine the structure, material, and visualization in one process and give the digital model for manufacture. From the given model, it is concluded that the method is effective for HEO. Using microdroplet rapid prototyping and the model given in the paper HEO could be gotten basically. The model could be used in 3D biomanufacturing.

  20. Decomposition recovery extension to the Computer Aided Prototyping System (CAPS) change-merge tool.

    OpenAIRE

    Keesling, William Ronald

    1997-01-01

    Approved for public release; distribution is unlimited A promising use of Computer Aided Prototyping System (CAPS) is to support concurrent design. Key to success in this context is the ability to automatically and reliably combine and integrate the prototypes produced in concurrent efforts. Thus, to be of practical use in this as well as most prototyping contexts, a CAPS tool must have a fast, automated, reliable prototype integration capability. The current CAPS Change Merge Tool is fast...

  1. A swarm-trained k-nearest prototypes adaptive classifier with automatic feature selection for interval data.

    Science.gov (United States)

    Silva Filho, Telmo M; Souza, Renata M C R; Prudêncio, Ricardo B C

    2016-08-01

    Some complex data types are capable of modeling data variability and imprecision. These data types are studied in the symbolic data analysis field. One such data type is interval data, which represents ranges of values and is more versatile than classic point data for many domains. This paper proposes a new prototype-based classifier for interval data, trained by a swarm optimization method. Our work has two main contributions: a swarm method which is capable of performing both automatic selection of features and pruning of unused prototypes and a generalized weighted squared Euclidean distance for interval data. By discarding unnecessary features and prototypes, the proposed algorithm deals with typical limitations of prototype-based methods, such as the problem of prototype initialization. The proposed distance is useful for learning classes in interval datasets with different shapes, sizes and structures. When compared to other prototype-based methods, the proposed method achieves lower error rates in both synthetic and real interval datasets. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. APPLICATION OF ADDITIVELY MANUFACTURED POLYMER COMPOSITE PROTOTYPES IN FOUNDRY

    Directory of Open Access Journals (Sweden)

    Wiesław Kuczko

    2015-05-01

    Full Text Available The paper presents a method, developed by the authors, for manufacturing polymer composites with the matrix manufactured in a layered manner (via 3D printing – Fused Deposition Modeling out of a thermoplastic material. As an example of practical application of this method, functional prototypes are presented, which were used as elements of foundry tooling – patterns for sand molding. In case of manufacturing prototype castings or short series of products, foundries usually cooperate with modeling studios, which produce patterns by conventional, subtractive manufacturing technologies. If patterns have complex shapes, this results in high manufacturing costs and significantly longer time of tooling preparation. The method proposed by the authors allows manufacturing functional prototypes in a short time thanks to utilizing capabilities of additive manufacturing (3D printing technology. Thanks to using two types of materials simultaneously (ABS combined with chemically hardened resins, the produced prototypes are capable of carrying increased loads. Moreover, the method developed by the authors is characterized by manufacturing costs lower than in the basic technology of Fused Deposition Modeling. During the presented studies, the pattern was produced as a polymer composite and it was used to prepare a mold and a set of metal castings.

  3. AN INTRODUCTION TO RAPID CASTING: DEVELOPMENT AND INVESTIGATION OF PROCESS CHAINS FOR SAND CASTING OF FUNCTIONAL PROTOTYPES

    Directory of Open Access Journals (Sweden)

    D. Dimitrov

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: This paper discusses the results obtained from studies on different Rapid Tooling process chains in order to improve the design and manufacture of foundry equipment that is used for sand casting of prototypes in final material. These prototypes are intended for functional and pre-production tests of vehicles. The Three Dimensional Printing process is used as core technology. Subsequently, while considering aspects such as time, cost, quality (accuracy and surface roughness, and tool life, a framework is presented for the evaluation and selection of the most suitable process chain in accordance with specific requirements. This research builds on an in-depth characterisation of the accuracy and repeatability of a 3D printing process.

    AFRIKAANSE OPSOMMING: Hierdie artikel bespreek die resultate wat verkry is tydens studies op verskillende Snel-Gereedskapvervaardigingproseskettings wat ondersoek is teneinde die ontwerp en vervaardiging van sandgietgereedskap, om prototipes in finale materiaal te vervaardig, te verbeter. Die prototipes is bestem vir gebruik in funksionele- en voorproduksietoetse van voertuie. Die sogenaamde Driedimensionele Drukproses (3DP is as kerntegnologie aangewend. Gevolglik, na oorweging van aspekte soos tyd, koste, kwaliteit (akkuraatheid en oppervlakafwerking, en gereedskapleeftyd, is ’n raamwerk ontwikkel vir die evaluering en seleksie van die mees geskikte prosesketting met inagname van spesifieke vereistes. Hierdie navorsing bou op ’n diepgaande karakterisering van die akkuraatheids- en herhaalbaarheidsvermoë van ’n 3D drukproses.

  4. Prototype and proposed ISABELLE dipoles

    International Nuclear Information System (INIS)

    McInturff, A.D.; Sampson, W.B.; Robins, K.E.; Dahl, P.F.; Damm, R.

    1977-01-01

    Data are presented on the latest dipole prototypes to update the operational parameters possible for ISABELLE. This data base will constantly expand until the start of construction of the storage rings. The data will include field quality, stray field magnitudes, quench temperature and propagation times, protection capabilities singly and in multiple units, maximum central fields obtained and training behavior. Performance of the dipoles versus temperature and mode of refrigeration will be discussed. The single layer cosine theta turns distribution coils' parameters are better than those required for the operation of the 200 x 200 GeV version of ISABELLE. The double layer prototype has exceeded the magnetic field performance and two dimensional quality of field needed for the 400 x 400 GeV version of ISABELLE

  5. Column Stores as an IR Prototyping Tool

    NARCIS (Netherlands)

    H.F. Mühleisen (Hannes); T. Samar (Thaer); J.J.P. Lin (Jimmy); A.P. de Vries (Arjen)

    2014-01-01

    textabstract. We make the suggestion that instead of implementing custom index structures and query evaluation algorithms, IR researchers should simply store document representations in a column-oriented relational database and write ranking models using SQL. For rapid prototyping, this is

  6. COSY Control Status. First results with rapid prototyped man-machine interface for accelerator control

    Energy Technology Data Exchange (ETDEWEB)

    Hacker, U [Forschungszentrum Juelich, Postfach 1913, 52425 Juelich (Germany); Haberbosch, C [Forschungszentrum Juelich, Postfach 1913, 52425 Juelich (Germany); Henn, K [Forschungszentrum Juelich, Postfach 1913, 52425 Juelich (Germany); Weinert, A [Forschungszentrum Juelich, Postfach 1913, 52425 Juelich (Germany)

    1994-12-15

    The experience gained with the COSY Control System after a six month commissioning period followed by a six month production period will be presented. The COSY Control System runs approximately 300 VME and VXI target systems using a total of about 1000 CPUs, the systems are driven by the diskless operating environment RT/OS, hosted by eight workcells. Application software is implemented using Object-Orientated programming paradigms. All accelerator components become interface functions as instances of an abstract device model class. Methods defined here present an abstract picture of the accelerator giving immediate access to device states and parameters. Operator interaction is defined by building views and controllers for the model. Higher level functions, such as defining an acceleration cycle, are easily developed and modified with the accelerator connected on-line to the model. In the first year of COSY operation the object based approach for a control system, together with a rapid prototyped man-machine interface has brought to light the potential of new functions such as on-line, real time programming on a running system yielding high programming performance. The advantages of this approach have not been, until now, fully appreciated. ((orig.))

  7. Application of the polystyrene model made by 3-D printing rapid prototyping technology for operation planning in revision lumbar discectomy.

    Science.gov (United States)

    Li, Chao; Yang, Mingyuan; Xie, Yang; Chen, Ziqiang; Wang, Chuanfeng; Bai, Yushu; Zhu, Xiaodong; Li, Ming

    2015-05-01

    The objective was to evaluate the effectiveness of 3-D rapid prototyping technology in revision lumbar discectomy. 3-D rapid prototyping technology has not been reported in the treatment of revision lumbar discectomy. Patients with recurrent lumbar disc herniation who were preparing to undergo revision lumbar discectomy from a single center between January 2011 and 2013 were included in this analysis. Patients were divided into two groups. In group A, 3-D printing technology was used to create subject-specific lumbar vertebral models in the preoperative planning process. Group B underwent lumbar revision as usual. Preoperative and postoperative clinical outcomes were compared between groups included operation time, perioperative blood loss, postoperative complications, Oswestry Disability Index (ODI), Japan Orthopaedics Association (JOA) scores, and visual analogue scale (VAS) scores for back pain and leg pain. A total of 37 patients were included in this study (Group A = 15, Group B = 22). Group A had a significantly shorter operation time (106.53 ± 11.91 vs. 131.92 ± 10.81 min, P < 0.001) and significantly less blood loss (341.67 ± 49.45 vs. 466.77 ± 71.46 ml, P < 0.001). There was no difference between groups for complication rate. There were also no differences between groups for any clinical metric. Using the 3-D printing technology before revision lumbar discectomy may reduce the operation time and the perioperative blood loss. There does not appear to be a benefit to using the technology with respect to clinical outcomes. Future prospective studies are needed to further elucidate the efficacy of this emerging technology.

  8. Porous titanium scaffolds fabricated using a rapid prototyping and powder metallurgy technique.

    Science.gov (United States)

    Ryan, Garrett E; Pandit, Abhay S; Apatsidis, Dimitrios P

    2008-09-01

    One of the main issues in orthopaedic implant design is the fabrication of scaffolds that closely mimic the biomechanical properties of the surrounding bone. This research reports on a multi-stage rapid prototyping technique that was successfully developed to produce porous titanium scaffolds with fully interconnected pore networks and reproducible porosity and pore size. The scaffolds' porous characteristics were governed by a sacrificial wax template, fabricated using a commercial 3D-printer. Powder metallurgy processes were employed to generate the titanium scaffolds by filling around the wax template with titanium slurry. In the attempt to optimise the powder metallurgy technique, variations in slurry concentration, compaction pressure and sintering temperature were investigated. By altering the wax design template, pore sizes ranging from 200 to 400 microm were achieved. Scaffolds with porosities of 66.8 +/- 3.6% revealed compression strengths of 104.4+/-22.5 MPa in the axial direction and 23.5 +/- 9.6 MPa in the transverse direction demonstrating their anisotropic nature. Scaffold topography was characterised using scanning electron microscopy and microcomputed tomography. Three-dimensional reconstruction enabled the main architectural parameters such as pore size, interconnecting porosity, level of anisotropy and level of structural disorder to be determined. The titanium scaffolds were compared to their intended designs, as governed by their sacrificial wax templates. Although discrepancies in architectural parameters existed between the intended and the actual scaffolds, overall the results indicate that the porous titanium scaffolds have the properties to be potentially employed in orthopaedic applications.

  9. Software Prototyping: A Case Report of Refining User Requirements for a Health Information Exchange Dashboard.

    Science.gov (United States)

    Nelson, Scott D; Del Fiol, Guilherme; Hanseler, Haley; Crouch, Barbara Insley; Cummins, Mollie R

    2016-01-01

    Health information exchange (HIE) between Poison Control Centers (PCCs) and Emergency Departments (EDs) could improve care of poisoned patients. However, PCC information systems are not designed to facilitate HIE with EDs; therefore, we are developing specialized software to support HIE within the normal workflow of the PCC using user-centered design and rapid prototyping. To describe the design of an HIE dashboard and the refinement of user requirements through rapid prototyping. Using previously elicited user requirements, we designed low-fidelity sketches of designs on paper with iterative refinement. Next, we designed an interactive high-fidelity prototype and conducted scenario-based usability tests with end users. Users were asked to think aloud while accomplishing tasks related to a case vignette. After testing, the users provided feedback and evaluated the prototype using the System Usability Scale (SUS). Survey results from three users provided useful feedback that was then incorporated into the design. After achieving a stable design, we used the prototype itself as the specification for development of the actual software. Benefits of prototyping included having 1) subject-matter experts heavily involved with the design; 2) flexibility to make rapid changes, 3) the ability to minimize software development efforts early in the design stage; 4) rapid finalization of requirements; 5) early visualization of designs; 6) and a powerful vehicle for communication of the design to the programmers. Challenges included 1) time and effort to develop the prototypes and case scenarios; 2) no simulation of system performance; 3) not having all proposed functionality available in the final product; and 4) missing needed data elements in the PCC information system.

  10. Innovative procedure for computer-assisted genioplasty: three-dimensional cephalometry, rapid-prototyping model and surgical splint.

    Science.gov (United States)

    Olszewski, R; Tranduy, K; Reychler, H

    2010-07-01

    The authors present a new procedure of computer-assisted genioplasty. They determined the anterior, posterior and inferior limits of the chin in relation to the skull and face with the newly developed and validated three-dimensional cephalometric planar analysis (ACRO 3D). Virtual planning of the osteotomy lines was carried out with Mimics (Materialize) software. The authors built a three-dimensional rapid-prototyping multi-position model of the chin area from a medical low-dose CT scan. The transfer of virtual information to the operating room consisted of two elements. First, the titanium plates on the 3D RP model were pre-bent. Second, a surgical guide for the transfer of the osteotomy lines and the positions of the screws to the operating room was manufactured. The authors present the first case of the use of this model on a patient. The postoperative results are promising, and the technique is fast and easy-to-use. More patients are needed for a definitive clinical validation of this procedure. Copyright 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  11. Modelling cloud data for prototype manufacturing

    NARCIS (Netherlands)

    Liu, G.H.; Wong, Y.S.; Zhang, Y.F.; Loh, H.T.

    2003-01-01

    In this paper, the authors have developed a novel method to integrate reverse engineering (RE) and rapid prototyping (RP). Unorganised cloud data are directly sliced and modelled with two-dimensional (2D) cross-sections. Based on such a 2D CAD model, the data points are directly converted into RP

  12. Fabrication of a Cranial Prosthesis Combined with an Ocular Prosthesis Using Rapid Prototyping: A Case Report

    Directory of Open Access Journals (Sweden)

    Gayatri Shankaran

    2016-08-01

    Full Text Available Rapid prototyping (RP is a technique of manufacturing parts by the additive layer manufacturing technology; where, a three-dimensional (3D model created in a computer aided design (CAD system is sectioned into 2D profiles, which are further constructed by RP layer by layer. Its use is not limited to industrial or engineering fields and has extended to the medical field for the manufacturing of custom implants and prostheses, the study of anatomy and surgical planning. Nowadays, dentists are more frequently encountered with the individuals affected with craniofacial defects due to trauma. In such cases, the cranio-maxillofacial rehabilitation is a real challenge to bring the patients back to society and promote their well-being. The conventional impression technique for facial prosthesis fabrication has the disadvantage of deforming the soft tissue and causing discomfort for the patient. Herein, we describe the fabrication of a cranial prosthesis combined with an ocular prosthesis with RP and stereolithography.

  13. Fabrication of a Cranial Prosthesis Combined with an Ocular Prosthesis Using Rapid Prototyping: A Case Report.

    Science.gov (United States)

    Shankaran, Gayatri; Deogade, Suryakant Chhagan; Dhirawani, Rajesh

    2016-01-01

    Rapid prototyping (RP) is a technique of manufacturing parts by the additive layer manufacturing technology; where, a three-dimensional (3D) model created in a computer aided design (CAD) system is sectioned into 2D profiles, which are further constructed by RP layer by layer. Its use is not limited to industrial or engineering fields and has extended to the medical field for the manufacturing of custom implants and prostheses, the study of anatomy and surgical planning. Nowadays, dentists are more frequently encountered with the individuals affected with craniofacial defects due to trauma. In such cases, the craniomaxillofacial rehabilitation is a real challenge to bring the patients back to society and promote their well-being. The conventional impression technique for facial prosthesis fabrication has the disadvantage of deforming the soft tissue and causing discomfort for the patient. Herein, we describe the fabrication of a cranial prosthesis combined with an ocular prosthesis with RP and stereolithography.

  14. Rapid Turn-Around Flight Testing of a Next-Generation Prototype RNLV (Preprint)

    National Research Council Canada - National Science Library

    Garvey, John M; Besnard, Eric

    2008-01-01

    ...) with an earlier prototype RNLV first stage (the Prospector 7) that was developed under a Phase I SBIR sponsored by the Air Force Research Laboratory - Propulsion Directorate with support from the Air...

  15. The Strategic Fitness Process: A Collaborative Action Research Method for Developing and Understanding Organizational Prototypes and Dynamic Capabilities

    Directory of Open Access Journals (Sweden)

    Michael Beer

    2013-04-01

    Full Text Available Organizations underperform and sometimes fail because their leaders are unable to learn the unvarnished truth from relevant stakeholders about how the design and behavior of the organization is misaligned with its goals and strategy. The Strategic Fitness Process (SFP was designed to enable leaders to overcome organizational silence about the misalignment with the environment and chosen strategy. By enabling an honest, organization-wide and public conversation, senior management teams, working collaboratively with scholar-consultants and organizational members, have access to valid data (the unvarnished truth, can conduct a valid diagnosis, and can develop a valid plan to change the structure, processes, and behavior of an organization while at the same time developing commitment that ensures execution. SFP is also a research method. By applying SFP iteratively to new and challenging situations, scholar-consultants can invent new organizational prototypes as well as learn if a standardized and institutionalized organizational learning process like SFP can enhance dynamic capabilities. The SFP model is illustrated with an application to Hewlett-Packard’s Santa Rosa Systems Division.

  16. Utilization of virtual prototyping in development of CMM

    International Nuclear Information System (INIS)

    Raneda, A.; Pessi, P.; Siuko, M.; Handroos, H.; Palmer, J.; Vilenius, M.

    2003-01-01

    The characteristic advantages of hydraulics (high power density, simple construction and reliability) together with the characteristics of water as the pressure medium (fire and environmentally safe, chemically neutral, not activated nor affected by radiation) are highlighted in critical applications such as remote handling operations in International Thermonuclear Experimental Reactor (ITER). However, component cost and lack of wide selection of water hydraulic components make it difficult to build and to test complex water hydraulic systems. The use of virtual prototyping for the development of water hydraulic tools can be used to address this problem. Rapidly increased computational power has created conditions for extensive numerical calculations, enabling computer aided virtual prototyping to replace physical prototype phases in product development

  17. Usefulness of Computed Tomography in pre-surgical evaluation of maxillo-facial pathology with rapid prototyping and surgical pre-planning by virtual reality

    International Nuclear Information System (INIS)

    Toso, Francesco; Zuiani, Chiara; Vergendo, Maurizio; Bazzocchi, Massimo; Salvo, Iolanda; Robiony, Massimo; Politi, Massimo

    2005-01-01

    Purpose. To validate a protocol for creating virtual models to be used in the construction of solid prototypes useful for the planning-simulation of maxillo-facial surgery, in particular for very complex anatomical and pathologic problems. To optimize communications between the radiology, engineering and surgical laboratories. Methods and materials. We studied 16 patients with different clinical problems of the maxillo-facial district. Exams were performed with multidetector computed tomography (MDCT) and single slice computed tomography (SDCT) with axial scans and collimation of 0.5-2 mm, and reconstruction interval of 1 mm. Subsequently we performed 2D multiplanar reconstructions and 3D volume-rendering reconstructions. We exported the DICOM images to the engineering laboratory, to recognize and isolate the bony structures by software. With these data the solid prototypes were generated using stereolitography. To date, surgery has been preformed on 12 patients after simulation of the procedure on the stereolitography model. Results. The solid prototypes constructed in the difficult cases were sufficiently detailed despite problems related to the artefacts generated by dental fillings and prostheses. In the remaining cases the MPR/3D images were sufficiently detailed for surgical planning. The surgical results were excellent in all patients who underwent surgery, and the surgeons were satisfied with the improvement in quality and the reduction in time required for the procedure. Conclusions. MDCT enables rapid prototyping using solid replication, which was very helpful in maxillofacial surgery, despite problems related to artifacts due to dental fillings and prosthesis within the acquisition field; solutions for this problem are work in progress. The protocol used for communication between the different laboratories was valid and reproducible [it

  18. Rehabilitation of the nose using CAD/CAM and rapid prototyping technology after ablative surgery of squamous cell carcinoma: a pilot clinical report.

    Science.gov (United States)

    Ciocca, Leonardo; De Crescenzio, Francesca; Fantini, Massimiliano; Scotti, Roberto

    2010-01-01

    Restoration of a nasal defect after ablative surgery for squamous cell carcinoma necessitates replacing the missing volume and anchoring a prosthesis to the patient's face. This report describes the failure of plastic reconstructive surgery after ablation of a squamous cell cancer of the nose and the esthetic and functional restoration of the patient with a nasal prosthesis. The process of making an implant-supported prosthesis using digital technology, including digitized anatomic models from a "nose library," and the rapid prototyping of the mesiostructure for bar anchorage and of the mold for silicone processing are presented.

  19. Ion beam surface treatment: A new capability for rapid melt and resolidification of surfaces

    International Nuclear Information System (INIS)

    Stinnett, R.W.; McIntyre, D.C.; Buchheit, R.G.; Greenly, J.B.; Thompson, M.O.

    1994-01-01

    The emerging capability to produce high average power (5--250 kW) pulsed ion beams at 0.2--2 MeV energies is enabling us to develop a new, commercial-scale thermal surface treatment technology called Ion Beam Surface Treatment (IBEST). This technique uses high energy, pulsed (≤100 ns) ion beams to directly deposit energy in the top 2--20 micrometers of the surface of any material. Depth of treatment is controllable by varying the ion energy and species. Deposition of the energy with short pulses in a thin surface layer allows melting of the layer with relatively small energies and allows rapid cooling of the melted layer by thermal diffusion into the underlying substrate. Typical cooling rates of this process (10 9 10 10 K/sec) cause rapid resolidification, resulting in production of non-equilibrium microstructures (nano-crystalline and metastable phases) that have significantly improved corrosion, wear, and hardness properties. We have conducted IBEST feasibility experiments with results confirming surface hardening, nanocrystaline grain formation, metal surface polishing, controlled melt of ceramic surfaces, and surface cleaning

  20. Prototype tests for a highly granular scintillator-based hadronic calorimeter

    OpenAIRE

    Liu, Yong; Collaboration, for the CALICE

    2017-01-01

    Within the CALICE collaboration, several concepts for the hadronic calorimeter of a future lepton collider detector are studied. After having demonstrated the capabilities of the measurement methods in "physics prototypes", the focus now lies on improving their implementation in "technological prototypes", that are scalable to the full linear collider detector. The Analogue Hadronic Calorimeter (AHCAL) concept is a sampling calorimeter of tungsten or steel absorber plates and plastic scintill...

  1. MPACT Fast Neutron Multiplicity System Prototype Development

    Energy Technology Data Exchange (ETDEWEB)

    D.L. Chichester; S.A. Pozzi; J.L. Dolan; M.T. Kinlaw; S.J. Thompson; A.C. Kaplan; M. Flaska; A. Enqvist; J.T. Johnson; S.M. Watson

    2013-09-01

    This document serves as both an FY2103 End-of-Year and End-of-Project report on efforts that resulted in the design of a prototype fast neutron multiplicity counter leveraged upon the findings of previous project efforts. The prototype design includes 32 liquid scintillator detectors with cubic volumes 7.62 cm in dimension configured into 4 stacked rings of 8 detectors. Detector signal collection for the system is handled with a pair of Struck Innovative Systeme 16-channel digitizers controlled by in-house developed software with built-in multiplicity analysis algorithms. Initial testing and familiarization of the currently obtained prototype components is underway, however full prototype construction is required for further optimization. Monte Carlo models of the prototype system were performed to estimate die-away and efficiency values. Analysis of these models resulted in the development of a software package capable of determining the effects of nearest-neighbor rejection methods for elimination of detector cross talk. A parameter study was performed using previously developed analytical methods for the estimation of assay mass variance for use as a figure-of-merit for system performance. A software package was developed to automate these calculations and ensure accuracy. The results of the parameter study show that the prototype fast neutron multiplicity counter design is very nearly optimized under the restraints of the parameter space.

  2. Rapid Tooling via Stereolithography

    OpenAIRE

    Montgomery, Eva

    2006-01-01

    Approximately three years ago, composite stereolithography (SL) resins were introduced to the marketplace, offering performance features beyond what traditional SL resins could offer. In particular, the high heat deflection temperatures and high stiffness of these highly filled resins have opened the door to several new rapid prototyping (RP) applications, including wind tunnel test modelling and, more recently, rapid tooling.

  3. Radiation Tests of Real-Sized Prototype RPCs for the Future CMS RPC Upscope

    CERN Document Server

    Lee, K.S.; Choi, S.Y.; Hong, B.; Go, Y.; Kang, M.H.; Lim, J.H.; Park, S.K.; Cimmino, A.; Crucy, S.; Fagot, A.; Gul, M.; Rios, A.A.O.; Tytgat, M.; Zaganidis, N.; Aly, S.; Assran, Y.; Radi, A.; Sayed, A.; Singh, G.; Abbrescia, M.; Iaselli, G.; Maggi, M.; Pugliese, G.; Verwilligen, P.; Doninck, W.van; Colafranceschi, S.; Sharma, A.; Benussi, L.; Bianco, S.; Piccolo, D.; Primavera, F.; Bhatnagar, V.; Kumarl, R.; Metha, A.; Singh, J.; Ahmad, A.; Ahmad, M.; Ahmed, W.; Asghar, M.I.; Awan, I.M.; Hassan, Q.; Hoorani, H.; Khan, W.A.; Khurshid, T.; Muhammad, S.; Shah, M.A.; Shahzad, H.; Kim, M.S.; Goutzvitz, M.; Grenier, G.; Lagarde, F.; Laktineh, I.B.; Carpinteyro Bernardino, S.; Uribe Estrada, C.; Pedraza, I.; Severiano, C.B.; Carrillo Moreno, S.; Vazquez Valencia, F.; Pant, L.M.; Buontempo, S.; Cavallo, N.; Esposito, M.; Fabozzi, F.; Lanza, G.; Lista, L.; Meola, S.; Merola, M.; Orso, I.; Paolucci, P.; Thyssen, F.; Braghieri, A.; Magnani, A.; Montagna, P.; Riccardi, C.; Salvini, P.; Vai, I.; Vitulo, P.; Ban, Y.; Qian, S.J.; Choi, M.; Choi, Y.; Goh, J.; Kim, D.; Aleksandrov, A.; Hadjiiska, R.; Iaydjiev, P.; Rodozov, M.; Stoykova, S.; Sultanov, G.; Vutova, M.; Dimitrov, A.; Litov, L.; Pavlov, B.; Petkov, P.; Lomidze, D.; Avila, C.; Cabrera, A.; Sanabria, J.C.; Crotty, I.; Vaitkus, J.

    2016-08-10

    We report on a systematic study of double-gap and four-gap phenolic resistive plate chambers (RPCs) for future high-{\\eta} RPC triggers in the CMS. In the present study, we constructed real-sized double-gap and four-gap RPCs with gap thicknesses of 1.6 and 0.8 mm, respectively, with 2-mm-thick phenolic high-pressure-laminated (HPL) plates. We examined the prototype RPCs for cosmic rays and 100 GeV muons provided by the SPS H4 beam line at CERN. We applied maximum gamma rates of 1.5 kHz cm-2 provided by 137Cs sources at Korea University and the GIF++ irradiation facility installed at the SPS H4 beam line to examine the rate capabilities of the prototype RPCs. In contrast to the case of the four-gap RPCs, we found the relatively high threshold was conducive to effectively suppressing the rapid increase of strip cluster sizes of muon hits with high voltage, especially when measuring the narrow-pitch strips. The gamma-induced currents drawn in the four-gap RPC were about one-fourth of those drawn in the double-ga...

  4. 3D Rapid Prototyping for Otolaryngology-Head and Neck Surgery: Applications in Image-Guidance, Surgical Simulation and Patient-Specific Modeling.

    Science.gov (United States)

    Chan, Harley H L; Siewerdsen, Jeffrey H; Vescan, Allan; Daly, Michael J; Prisman, Eitan; Irish, Jonathan C

    2015-01-01

    The aim of this study was to demonstrate the role of advanced fabrication technology across a broad spectrum of head and neck surgical procedures, including applications in endoscopic sinus surgery, skull base surgery, and maxillofacial reconstruction. The initial case studies demonstrated three applications of rapid prototyping technology are in head and neck surgery: i) a mono-material paranasal sinus phantom for endoscopy training ii) a multi-material skull base simulator and iii) 3D patient-specific mandible templates. Digital processing of these phantoms is based on real patient or cadaveric 3D images such as CT or MRI data. Three endoscopic sinus surgeons examined the realism of the endoscopist training phantom. One experienced endoscopic skull base surgeon conducted advanced sinus procedures on the high-fidelity multi-material skull base simulator. Ten patients participated in a prospective clinical study examining patient-specific modeling for mandibular reconstructive surgery. Qualitative feedback to assess the realism of the endoscopy training phantom and high-fidelity multi-material phantom was acquired. Conformance comparisons using assessments from the blinded reconstructive surgeons measured the geometric performance between intra-operative and pre-operative reconstruction mandible plates. Both the endoscopy training phantom and the high-fidelity multi-material phantom received positive feedback on the realistic structure of the phantom models. Results suggested further improvement on the soft tissue structure of the phantom models is necessary. In the patient-specific mandible template study, the pre-operative plates were judged by two blinded surgeons as providing optimal conformance in 7 out of 10 cases. No statistical differences were found in plate fabrication time and conformance, with pre-operative plating providing the advantage of reducing time spent in the operation room. The applicability of common model design and fabrication techniques

  5. NGNP Component Test Capability Design Code of Record

    Energy Technology Data Exchange (ETDEWEB)

    S.L. Austad; D.S. Ferguson; L.E. Guillen; C.W. McKnight; P.J. Petersen

    2009-09-01

    The Next Generation Nuclear Plant Project is conducting a trade study to select a preferred approach for establishing a capability whereby NGNP technology development testing—through large-scale, integrated tests—can be performed for critical HTGR structures, systems, and components (SSCs). The mission of this capability includes enabling the validation of interfaces, interactions, and performance for critical systems and components prior to installation in the NGNP prototype.

  6. Rapid lard identification with portable electronic nose

    Science.gov (United States)

    Latief, Marsad; Khorsidtalab, Aida; Saputra, Irwan; Akmeliawati, Rini; Nurashikin, Anis; Jaswir, Irwandi; Witjaksono, Gunawan

    2017-11-01

    Human sensory systems are limited in many different regards, yet they are great sources of inspiration for development of technologies that help humans to overcome their restraints. This paper signifies the capability of our developed electronic nose in rapid lard identification. The developed device, known as E-Nose, mimics human’s olfactory system’s technique to identify a particular substance. Lard is a common pig derivative which is often used as a food additive, emulsion or shortening. It’s also commonly used as an adulterant or as an alternative for cooking oils, margarine and butter. This substance is prohibited to be consumed by Muslims and Orthodox Jews for religious reasons. A portable reliable device with an ability to identify lard rapidly can be convenient to users concerned about lard adulteration. The prototype was examined using K-Nearest Neighbors algorithm (KNN), Support Vector Machine (SVM), Bagged Trees and Simple Tree, and can identify lard with the highest accuracy of 95.6% among three types of fat (lard, chicken and beef) in liquid form over a certain range of temperature using KNN.

  7. New Design for Rapid Prototyping of Digital Master Casts for Multiple Dental Implant Restorations.

    Directory of Open Access Journals (Sweden)

    Luis Romero

    Full Text Available This study proposes the replacement of all the physical devices used in the manufacturing of conventional prostheses through the use of digital tools, such as 3D scanners, CAD design software, 3D implants files, rapid prototyping machines or reverse engineering software, in order to develop laboratory work models from which to finish coatings for dental prostheses. Different types of dental prosthetic structures are used, which were adjusted by a non-rotatory threaded fixing system.From a digital process, the relative positions of dental implants, soft tissue and adjacent teeth of edentulous or partially edentulous patients has been captured, and a maser working model which accurately replicates data relating to the patients oral cavity has been through treatment of three-dimensional digital data.Compared with the conventional master cast, the results show a significant cost savings in attachments, as well as an increase in the quality of reproduction and accuracy of the master cast, with the consequent reduction in the number of patient consultation visits. The combination of software and hardware three-dimensional tools allows the optimization of the planning of dental implant-supported rehabilitations protocol, improving the predictability of clinical treatments and the production cost savings of master casts for restorations upon implants.

  8. New Design for Rapid Prototyping of Digital Master Casts for Multiple Dental Implant Restorations.

    Science.gov (United States)

    Romero, Luis; Jiménez, Mariano; Espinosa, María Del Mar; Domínguez, Manuel

    2015-01-01

    This study proposes the replacement of all the physical devices used in the manufacturing of conventional prostheses through the use of digital tools, such as 3D scanners, CAD design software, 3D implants files, rapid prototyping machines or reverse engineering software, in order to develop laboratory work models from which to finish coatings for dental prostheses. Different types of dental prosthetic structures are used, which were adjusted by a non-rotatory threaded fixing system. From a digital process, the relative positions of dental implants, soft tissue and adjacent teeth of edentulous or partially edentulous patients has been captured, and a maser working model which accurately replicates data relating to the patients oral cavity has been through treatment of three-dimensional digital data. Compared with the conventional master cast, the results show a significant cost savings in attachments, as well as an increase in the quality of reproduction and accuracy of the master cast, with the consequent reduction in the number of patient consultation visits. The combination of software and hardware three-dimensional tools allows the optimization of the planning of dental implant-supported rehabilitations protocol, improving the predictability of clinical treatments and the production cost savings of master casts for restorations upon implants.

  9. New Design for Rapid Prototyping of Digital Master Casts for Multiple Dental Implant Restorations

    Science.gov (United States)

    Romero, Luis; Jiménez, Mariano; Espinosa, María del Mar; Domínguez, Manuel

    2015-01-01

    Aim This study proposes the replacement of all the physical devices used in the manufacturing of conventional prostheses through the use of digital tools, such as 3D scanners, CAD design software, 3D implants files, rapid prototyping machines or reverse engineering software, in order to develop laboratory work models from which to finish coatings for dental prostheses. Different types of dental prosthetic structures are used, which were adjusted by a non-rotatory threaded fixing system. Method From a digital process, the relative positions of dental implants, soft tissue and adjacent teeth of edentulous or partially edentulous patients has been captured, and a maser working model which accurately replicates data relating to the patients oral cavity has been through treatment of three-dimensional digital data. Results Compared with the conventional master cast, the results show a significant cost savings in attachments, as well as an increase in the quality of reproduction and accuracy of the master cast, with the consequent reduction in the number of patient consultation visits. The combination of software and hardware three-dimensional tools allows the optimization of the planning of dental implant-supported rehabilitations protocol, improving the predictability of clinical treatments and the production cost savings of master casts for restorations upon implants. PMID:26696528

  10. Controls and interlocks for a prototype 1MHz beam chopper

    International Nuclear Information System (INIS)

    Waters, G.; Bishop, D.; Barnes, M.J.; Wait, G.D.

    1991-05-01

    A prototype 1 MHz beam chopper for the proposed KAON Factory at TRIUMF has been constructed. The chopper is an electric field device, driven by a tetrode based pulser, for deflecting a charged particle beam. Associated with the tetrode used in the prototype design are high voltage power supplies for the electrodes. We use an FET based grid pulser and a sequencer capable of accurate digital control of pulse timing to 0.4 ns. A safety interlock and control system using a programmable controller with fibre optic links has been built. This has given us the versatility required in a prototype system. (Author) 4 refs., 5 figs

  11. Elaboration on an Integrated Architecture and Requirement Practice: Prototyping with Quality Attribute Focus

    Science.gov (United States)

    2013-05-01

    release level prototyping as:  The R&D prototype is typically funded by the organization, rather than the client .  The work is done in an R&D...performance) with hopes that this capability could be offered to multiple clients . The clustering prototype is developed in the organization’s R&D...ICSE Conference 2013) [5] A. Martini, L. Pareto , and J. Bosch, “Enablers and inhibitors for speed with reuse,” Proceedings of the 16th Software

  12. [COMPUTER ASSISTED DESIGN AND ELECTRON BEAMMELTING RAPID PROTOTYPING METAL THREE-DIMENSIONAL PRINTING TECHNOLOGY FOR PREPARATION OF INDIVIDUALIZED FEMORAL PROSTHESIS].

    Science.gov (United States)

    Liu, Hongwei; Weng, Yiping; Zhang, Yunkun; Xu, Nanwei; Tong, Jing; Wang, Caimei

    2015-09-01

    To study the feasibility of preparation of the individualized femoral prosthesis through computer assisted design and electron beammelting rapid prototyping (EBM-RP) metal three-dimensional (3D) printing technology. One adult male left femur specimen was used for scanning with 64-slice spiral CT; tomographic image data were imported into Mimics15.0 software to reconstruct femoral 3D model, then the 3D model of individualized femoral prosthesis was designed through UG8.0 software. Finally the 3D model data were imported into EBM-RP metal 3D printer to print the individualized sleeve. According to the 3D model of individualized prosthesis, customized sleeve was successfully prepared through the EBM-RP metal 3D printing technology, assembled with the standard handle component of SR modular femoral prosthesis to make the individualized femoral prosthesis. Customized femoral prosthesis accurately matching with metaphyseal cavity can be designed through the thin slice CT scanning and computer assisted design technology. Titanium alloy personalized prosthesis with complex 3D shape, pore surface, and good matching with metaphyseal cavity can be manufactured by the technology of EBM-RP metal 3D printing, and the technology has convenient, rapid, and accurate advantages.

  13. Rapid prototyping of outdoor games for children in an iterative design process

    NARCIS (Netherlands)

    Soute, I.A.C.; Lagerström, S.; Markopoulos, P.

    2013-01-01

    This paper reflects on the design process of games that are played by multiple players, involving high pace activity and embodied interaction. More specifically it argues that user testing with low fidelity prototypes, which is recommended in mainstream literature on methodology in the fields of

  14. Description and performance of a prototype PET system for small volume imaging

    International Nuclear Information System (INIS)

    McKee, B.T.A.; Hogan, M.J.; Queen's Univ., Kingston, Ontario; Dinsdale, H.B.; Howse, D.C.N.; Kulick, J.; Mak, H.B.; Stewart, H.B.

    1988-01-01

    A prototype positron emission tomography (PET) system has been designed for high-resolution imaging of small volumes. The detectors use Pb converter stacks and multiwire proportional counters (MWPC); the data acquisition components and image reconstruction methods are also described briefly. The performance of the system is discussed in terms of sensitivity, count rate capability, spatial resolution, and scattered background. Three examples of metabolic or transport imaging demonstrate the capabilities and limitations of the system. These are blood flow to bone, cerebral glucose uptake, and nutrient translocation in plants. The performance of the prototype has been sufficiently promising that an improved system is under development. (orig.)

  15. A Methodology for Rapid Prototyping Peak-Constrained Least-Squares Bit-Serial Finite Impulse Response Filters in FPGAs

    Directory of Open Access Journals (Sweden)

    Alex Carreira

    2003-05-01

    Full Text Available Area-efficient peak-constrained least-squares (PCLS bit-serial finite impulse response (FIR filter implementations can be rapidly prototyped in field programmable gate arrays (FPGA with the methodology presented in this paper. Faster generation of the FPGA configuration bitstream is possible with a new application-specific mapping and placement method that uses JBits to avoid conventional general-purpose mapping and placement tools. JBits is a set of Java classes that provide an interface into the Xilinx Virtex FPGA configuration bitstream, allowing the user to generate new configuration bitstreams. PCLS coefficient generation allows passband-to-stopband energy ratio (PSR performance to be traded for a reduction in the filter's hardware cost without altering the minimum stopband attenuation. Fixed-point coefficients that meet the frequency response and hardware cost specifications can be generated with the PCLS method. It is not possible to meet these specifications solely by the quantization of floating-point coefficients generated in other methods.

  16. Preoperative planning of thoracic surgery with use of three-dimensional reconstruction, rapid prototyping, simulation and virtual navigation

    Science.gov (United States)

    Heuts, Samuel; Maessen, Jos G.

    2016-01-01

    For the past decades, surgeries have become more complex, due to the increasing age of the patient population referred for thoracic surgery, more complex pathology and the emergence of minimally invasive thoracic surgery. Together with the early detection of thoracic disease as a result of innovations in diagnostic possibilities and the paradigm shift to personalized medicine, preoperative planning is becoming an indispensable and crucial aspect of surgery. Several new techniques facilitating this paradigm shift have emerged. Pre-operative marking and staining of lesions are already a widely accepted method of preoperative planning in thoracic surgery. However, three-dimensional (3D) image reconstructions, virtual simulation and rapid prototyping (RP) are still in development phase. These new techniques are expected to become an important part of the standard work-up of patients undergoing thoracic surgery in the future. This review aims at graphically presenting and summarizing these new diagnostic and therapeutic tools PMID:29078505

  17. Contingency Contractor Optimization Phase 3 Sustainment Platform Requirements - Contingency Contractor Optimization Tool - Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Durfee, Justin David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Frazier, Christopher Rawls [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bandlow, Alisa [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Katherine A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-06-01

    Sandia National Laboratories (Sandia) is in Phase 3 Sustainment of development of a prototype tool, currently referred to as the Contingency Contractor Optimization Tool - Prototype (CCOTP), under the direction of OSD Program Support. CCOT-P is intended to help provide senior Department of Defense (DoD) leaders with comprehensive insight into the global availability, readiness and capabilities of the Total Force Mix. The CCOT-P will allow senior decision makers to quickly and accurately assess the impacts, risks and mitigating strategies for proposed changes to force/capabilities assignments, apportionments and allocations options, focusing specifically on contingency contractor planning. During Phase 2 of the program, conducted during fiscal year 2012, Sandia developed an electronic storyboard prototype of the Contingency Contractor Optimization Tool that can be used for communication with senior decision makers and other Operational Contract Support (OCS) stakeholders. Phase 3 used feedback from demonstrations of the electronic storyboard prototype to develop an engineering prototype for planners to evaluate. Sandia worked with the DoD and Joint Chiefs of Staff strategic planning community to get feedback and input to ensure that the engineering prototype was developed to closely align with future planning needs. The intended deployment environment was also a key consideration as this prototype was developed. Initial release of the engineering prototype was done on servers at Sandia in the middle of Phase 3. In 2013, the tool was installed on a production pilot server managed by the OUSD(AT&L) eBusiness Center. The purpose of this document is to specify the CCOT-P engineering prototype platform requirements as of May 2016. Sandia developed the CCOT-P engineering prototype using common technologies to minimize the likelihood of deployment issues. CCOT-P engineering prototype was architected and designed to be as independent as possible of the major deployment

  18. Deep Proton Writing for the rapid prototyping of polymer micro-components for optical interconnects and optofluidics

    Science.gov (United States)

    Van Erps, Jürgen; Vervaeke, Michael; Ottevaere, Heidi; Hermanne, Alex; Thienpont, Hugo

    2013-07-01

    The use of photonics in data communication and numerous other industrial applications brought plenty of prospects for innovation and opened up different unexplored market opportunities. This is a major driving force for the fabrication of micro-optical and micro-mechanical structures and their accurate alignment and integration into opto-mechanical modules and systems. To this end, we present Deep Proton Writing (DPW) as a powerful rapid prototyping technology for such micro-components. The DPW process consists of bombarding polymer samples (PMMA or SU-8) with swift protons, which results after chemical processing steps in high-quality micro-optical components. One of the strengths of the DPW micro-fabrication technology is the ability to fabricate monolithic building blocks that include micro-optical and mechanical functionalities which can be precisely integrated into more complex photonic systems. In this paper we comment on how we shifted from using 8.3 to 16.5 MeV protons for DPW and give some examples of micro-optical and micro-mechanical components recently fabricated through DPW, targeting applications in optical interconnections and in optofluidics.

  19. Deep Proton Writing for the rapid prototyping of polymer micro-components for optical interconnects and optofluidics

    Energy Technology Data Exchange (ETDEWEB)

    Van Erps, Jürgen, E-mail: jurgen.van.erps@vub.ac.be; Vervaeke, Michael; Ottevaere, Heidi; Hermanne, Alex; Thienpont, Hugo

    2013-07-15

    The use of photonics in data communication and numerous other industrial applications brought plenty of prospects for innovation and opened up different unexplored market opportunities. This is a major driving force for the fabrication of micro-optical and micro-mechanical structures and their accurate alignment and integration into opto-mechanical modules and systems. To this end, we present Deep Proton Writing (DPW) as a powerful rapid prototyping technology for such micro-components. The DPW process consists of bombarding polymer samples (PMMA or SU-8) with swift protons, which results after chemical processing steps in high-quality micro-optical components. One of the strengths of the DPW micro-fabrication technology is the ability to fabricate monolithic building blocks that include micro-optical and mechanical functionalities which can be precisely integrated into more complex photonic systems. In this paper we comment on how we shifted from using 8.3 to 16.5 MeV protons for DPW and give some examples of micro-optical and micro-mechanical components recently fabricated through DPW, targeting applications in optical interconnections and in optofluidics.

  20. Quantumness-generating capability of quantum dynamics

    Science.gov (United States)

    Li, Nan; Luo, Shunlong; Mao, Yuanyuan

    2018-04-01

    We study quantumness-generating capability of quantum dynamics, where quantumness refers to the noncommutativity between the initial state and the evolving state. In terms of the commutator of the square roots of the initial state and the evolving state, we define a measure to quantify the quantumness-generating capability of quantum dynamics with respect to initial states. Quantumness-generating capability is absent in classical dynamics and hence is a fundamental characteristic of quantum dynamics. For qubit systems, we present an analytical form for this measure, by virtue of which we analyze several prototypical dynamics such as unitary dynamics, phase damping dynamics, amplitude damping dynamics, and random unitary dynamics (Pauli channels). Necessary and sufficient conditions for the monotonicity of quantumness-generating capability are also identified. Finally, we compare these conditions for the monotonicity of quantumness-generating capability with those for various Markovianities and illustrate that quantumness-generating capability and quantum Markovianity are closely related, although they capture different aspects of quantum dynamics.

  1. Application of analytical capability to predict rapid cladding cooling and quench during the blowdown phase of a large break loss-of-coolant accident

    International Nuclear Information System (INIS)

    Aksan, S.N.; Tolman, E.L.; Nelson, R.A.

    1983-01-01

    Large-break Experiments L2-2 and L2-3 conducted in the Loss-of-Fluid Test (LOFT) facility experienced core-wide rapid quenches early in the blowdown transients. To further investigate rapid cladding quenches, separate effects experiments using Semiscale solid-type electric heater rods were conducted in the LOFT Test Support Facility (LTSF) over a wide range of inlet coolant conditions. The analytical capability to predict the cladding temperature response from selected LTSF experiments estimated to bound the hydraulic conditions causing the LOFT early blowdown quenches was investigated using the RELAP4 computer code and was shown to be acceptable over the film boiling cooldown phase. This analytical capability was then used to investigate the behavior of nuclear fuel rods under the same hydraulic conditions. The calculations show that, under rapid cooling conditions, the behaviors of nuclear and electrical heater rods are significantly different because the nuclear rods are conduction limited, while the electrical rods are convection limited

  2. Virtual Reality based User Interface for Conceptual Design and Rapid Prototyping

    OpenAIRE

    Jadhav, Saurabh Subhash

    2017-01-01

    Computer Aided Design and Engineering (CAD/ CAE) tools currently available in the market have dramatically improved since their inception. In product development, CAD/ CAE has enabled the user to design, test, analyze and optimize the product virtually even before the first prototype is built. Use of direct modeling for product conceptualization allows the designer to create concept design iterations freely, quickly, flexibly and fast optimization. While modeling geometric databases have been...

  3. Prototype Hanford Surface Barrier: Design basis document

    International Nuclear Information System (INIS)

    Myers, D.R.; Duranceau, D.A.

    1994-11-01

    The Hanford Site Surface Barrier Development Program (BDP) was organized in 1985 to develop the technology needed to provide a long-term surface barrier capability for the Hanford Site and other arid sites. This document provides the basis of the prototype barrier. Engineers and scientists have momentarily frozen evolving barrier designs and incorporated the latest findings from BDP tasks. The design and construction of the prototype barrier has required that all of the various components of the barrier be brought together into an integrated system. This integration is particularly important because some of the components of the protective barreir have been developed independently of other barreir components. This document serves as the baseline by which future modifications or other barrier designs can be compared. Also, this document contains the minutes of meeting convened during the definitive design process in which critical decisions affecting the prototype barrier's design were made and the construction drawings

  4. Rapid tooling for functional prototyping of metal mold processes. CRADA final report

    Energy Technology Data Exchange (ETDEWEB)

    Zacharia, T.; Ludtka, G.M.; Bjerke, M.A.; Gray, W.H.

    1997-12-01

    The overall scope of this endeavor was to develop an integrated computer system, running on a network of heterogeneous computers, that would allow the rapid development of tool designs, and then use process models to determine whether the initial tooling would have characteristics which produce the prototype parts. The major thrust of this program for ORNL was the definition of the requirements for the development of the integrated die design system with the functional purpose to link part design, tool design, and component fabrication through a seamless software environment. The principal product would be a system control program that would coordinate the various application programs and implement the data transfer so that any networked workstation would be useable. The overall system control architecture was to be required to easily facilitate any changes, upgrades, or replacements of the model from either the manufacturing end or the design criteria standpoint. The initial design of such a program is described in the section labeled ``Control Program Design``. A critical aspect of this research was the design of the system flow chart showing the exact system components and the data to be transferred. All of the major system components would have been configured to ensure data file compatibility and transferability across the Internet. The intent was to use commercially available packages to model the various manufacturing processes for creating the die and die inserts in addition to modeling the processes for which these parts were to be used. In order to meet all of these requirements, investigative research was conducted to determine the system flow features and software components within the various organizations contributing to this project. This research is summarized.

  5. Rapid prototyping of solar-powered, battery-operated, atmospheric-pressure, sugar-cube size microplasma on hybrid, 3D chips for elemental analysis of liquid microsamples using a portable optical emission spectrometer

    Science.gov (United States)

    Zhang, X.; Karanassios, V.

    2012-06-01

    A solar-powered, battery-operated, atmospheric-pressure, self-igniting microplasma the size of a sugar-cube developed on a hybrid, 3d-chip is described. Rapid prototyping of the 3d-chip; some fundamental aspects and a brief characterization of its background spectral emission using a portable, fiber-optic spectrometer are discussed.

  6. Rapid Prototyping of Microbial Cell Factories via Genome-scale Engineering

    Science.gov (United States)

    Si, Tong; Xiao, Han; Zhao, Huimin

    2014-01-01

    Advances in reading, writing and editing genetic materials have greatly expanded our ability to reprogram biological systems at the resolution of a single nucleotide and on the scale of a whole genome. Such capacity has greatly accelerated the cycles of design, build and test to engineer microbes for efficient synthesis of fuels, chemicals and drugs. In this review, we summarize the emerging technologies that have been applied, or are potentially useful for genome-scale engineering in microbial systems. We will focus on the development of high-throughput methodologies, which may accelerate the prototyping of microbial cell factories. PMID:25450192

  7. Integrated System Health Management (ISHM): Systematic Capability Implementation

    Science.gov (United States)

    Figueroa, Fernando; Holland, Randy; Schmalzwel, John; Duncavage, Dan

    2006-01-01

    This paper provides a credible approach for implementation of ISHM capability in any system. The requirements and processes to implement ISHM capability are unique in that a credible capability is initially implemented at a low level, and it evolves to achieve higher levels by incremental augmentation. In contrast, typical capabilities, such as thrust of an engine, are implemented once at full Functional Capability Level (FCL), which is not designed to change during the life of the product. The approach will describe core ingredients (e.g. technologies, architectures, etc.) and when and how ISHM capabilities may be implemented. A specific architecture/taxonomy/ontology will be described, as well as a prototype software environment that supports development of ISHM capability. This paper will address implementation of system-wide ISHM as a core capability, and ISHM for specific subsystems as expansions and evolution, but always focusing on achieving an integrated capability.

  8. Architectures of prototypes and architectural prototyping

    DEFF Research Database (Denmark)

    Hansen, Klaus Marius; Christensen, Michael; Sandvad, Elmer

    1998-01-01

    together as a team, but developed a prototype that more than fulfilled the expectations of the shipping company. The prototype should: - complete the first major phase within 10 weeks, - be highly vertical illustrating future work practice, - continuously live up to new requirements from prototyping......This paper reports from experience obtained through development of a prototype of a global customer service system in a project involving a large shipping company and a university research group. The research group had no previous knowledge of the complex business of shipping and had never worked...... sessions with users, - evolve over a long period of time to contain more functionality - allow for 6-7 developers working intensively in parallel. Explicit focus on the software architecture and letting the architecture evolve with the prototype played a major role in resolving these conflicting...

  9. Collaborative Prototyping

    DEFF Research Database (Denmark)

    Bogers, Marcel; Horst, Willem

    2014-01-01

    of the prototyping process, the actual prototype was used as a tool for communication or development, thus serving as a platform for the cross-fertilization of knowledge. In this way, collaborative prototyping leads to a better balance between functionality and usability; it translates usability problems into design......This paper presents an inductive study that shows how collaborative prototyping across functional, hierarchical, and organizational boundaries can improve the overall prototyping process. Our combined action research and case study approach provides new insights into how collaborative prototyping...... can provide a platform for prototype-driven problem solving in early new product development (NPD). Our findings have important implications for how to facilitate multistakeholder collaboration in prototyping and problem solving, and more generally for how to organize collaborative and open innovation...

  10. A prototype home robot with an ambient facial interface to improve drug compliance.

    Science.gov (United States)

    Takacs, Barnabas; Hanak, David

    2008-01-01

    We have developed a prototype home robot to improve drug compliance. The robot is a small mobile device, capable of autonomous behaviour, as well as remotely controlled operation via a wireless datalink. The robot is capable of face detection and also has a display screen to provide facial feedback to help motivate patients and thus increase their level of compliance. An RFID reader can identify tags attached to different objects, such as bottles, for fluid intake monitoring. A tablet dispenser allows drug compliance monitoring. Despite some limitations, experience with the prototype suggests that simple and low-cost robots may soon become feasible for care of people living alone or in isolation.

  11. Visual Temporal Logic as a Rapid Prototying Tool

    DEFF Research Database (Denmark)

    Fränzle, Martin; Lüth, Karsten

    2001-01-01

    Within this survey article, we explain real-time symbolic timing diagrams and the ICOS tool-box supporting timing-diagram-based requirements capture and rapid prototyping. Real-time symbolic timing diagrams are a full-fledged metric-time temporal logic, but with a graphical syntax reminiscent...... of the informal timing diagrams widely used in electrical engineering. ICOS integrates a variety of tools, ranging from graphical specification editors over tautology checking and counterexample generation to code generators emitting C or VHDL, thus bridging the gap from formal specification to rapid prototype...

  12. Rethink! prototyping transdisciplinary concepts of prototyping

    CERN Document Server

    Nagy, Emilia; Stark, Rainer

    2016-01-01

    In this book, the authors describe the findings derived from interaction and cooperation between scientific actors employing diverse practices. They reflect on distinct prototyping concepts and examine the transformation of development culture in their fusion to hybrid approaches and solutions. The products of tomorrow are going to be multifunctional, interactive systems – and already are to some degree today. Collaboration across multiple disciplines is the only way to grasp their complexity in design concepts. This underscores the importance of reconsidering the prototyping process for the development of these systems, particularly in transdisciplinary research teams. “Rethinking Prototyping – new hybrid concepts for prototyping” was a transdisciplinary project that took up this challenge. The aim of this programmatic rethinking was to come up with a general concept of prototyping by combining innovative prototyping concepts, which had been researched and developed in three sub-projects: “Hybrid P...

  13. Package testing capabilities at the Pacific Northwest Laboratory

    International Nuclear Information System (INIS)

    Taylor, J.M.

    1993-01-01

    The purpose of this paper is to describe the package testing capabilities at the Pacific Northwest Laboratory (PNL). In the past all of the package testing that was performed at PNL was done on prototype or mocked up radioactive material packaging. Presently, we are developing the capability to perform testing on non-radioactive material packaging. The testing on the non-radioactive material packaging will be done to satisfy the new performance oriented packaging requirements (DOT Docket HM-181, 1991). This paper describes the equipment used to perform the performance oriented packaging tests and also describes some testing capability for testing radioactive material packaging

  14. 3D Rapid Prototyping for Otolaryngology-Head and Neck Surgery: Applications in Image-Guidance, Surgical Simulation and Patient-Specific Modeling.

    Directory of Open Access Journals (Sweden)

    Harley H L Chan

    Full Text Available The aim of this study was to demonstrate the role of advanced fabrication technology across a broad spectrum of head and neck surgical procedures, including applications in endoscopic sinus surgery, skull base surgery, and maxillofacial reconstruction. The initial case studies demonstrated three applications of rapid prototyping technology are in head and neck surgery: i a mono-material paranasal sinus phantom for endoscopy training ii a multi-material skull base simulator and iii 3D patient-specific mandible templates. Digital processing of these phantoms is based on real patient or cadaveric 3D images such as CT or MRI data. Three endoscopic sinus surgeons examined the realism of the endoscopist training phantom. One experienced endoscopic skull base surgeon conducted advanced sinus procedures on the high-fidelity multi-material skull base simulator. Ten patients participated in a prospective clinical study examining patient-specific modeling for mandibular reconstructive surgery. Qualitative feedback to assess the realism of the endoscopy training phantom and high-fidelity multi-material phantom was acquired. Conformance comparisons using assessments from the blinded reconstructive surgeons measured the geometric performance between intra-operative and pre-operative reconstruction mandible plates. Both the endoscopy training phantom and the high-fidelity multi-material phantom received positive feedback on the realistic structure of the phantom models. Results suggested further improvement on the soft tissue structure of the phantom models is necessary. In the patient-specific mandible template study, the pre-operative plates were judged by two blinded surgeons as providing optimal conformance in 7 out of 10 cases. No statistical differences were found in plate fabrication time and conformance, with pre-operative plating providing the advantage of reducing time spent in the operation room. The applicability of common model design and

  15. 3D Rapid Prototyping for Otolaryngology—Head and Neck Surgery: Applications in Image-Guidance, Surgical Simulation and Patient-Specific Modeling

    Science.gov (United States)

    Chan, Harley H. L.; Siewerdsen, Jeffrey H.; Vescan, Allan; Daly, Michael J.; Prisman, Eitan; Irish, Jonathan C.

    2015-01-01

    The aim of this study was to demonstrate the role of advanced fabrication technology across a broad spectrum of head and neck surgical procedures, including applications in endoscopic sinus surgery, skull base surgery, and maxillofacial reconstruction. The initial case studies demonstrated three applications of rapid prototyping technology are in head and neck surgery: i) a mono-material paranasal sinus phantom for endoscopy training ii) a multi-material skull base simulator and iii) 3D patient-specific mandible templates. Digital processing of these phantoms is based on real patient or cadaveric 3D images such as CT or MRI data. Three endoscopic sinus surgeons examined the realism of the endoscopist training phantom. One experienced endoscopic skull base surgeon conducted advanced sinus procedures on the high-fidelity multi-material skull base simulator. Ten patients participated in a prospective clinical study examining patient-specific modeling for mandibular reconstructive surgery. Qualitative feedback to assess the realism of the endoscopy training phantom and high-fidelity multi-material phantom was acquired. Conformance comparisons using assessments from the blinded reconstructive surgeons measured the geometric performance between intra-operative and pre-operative reconstruction mandible plates. Both the endoscopy training phantom and the high-fidelity multi-material phantom received positive feedback on the realistic structure of the phantom models. Results suggested further improvement on the soft tissue structure of the phantom models is necessary. In the patient-specific mandible template study, the pre-operative plates were judged by two blinded surgeons as providing optimal conformance in 7 out of 10 cases. No statistical differences were found in plate fabrication time and conformance, with pre-operative plating providing the advantage of reducing time spent in the operation room. The applicability of common model design and fabrication techniques

  16. Three-dimensional bioactive glass implants fabricated by rapid prototyping based on CO(2) laser cladding.

    Science.gov (United States)

    Comesaña, R; Lusquiños, F; Del Val, J; López-Álvarez, M; Quintero, F; Riveiro, A; Boutinguiza, M; de Carlos, A; Jones, J R; Hill, R G; Pou, J

    2011-09-01

    Three-dimensional bioactive glass implants were produced by rapid prototyping based on laser cladding without using moulds. CO(2) laser radiation was employed to melt 45S5 and S520 bioactive glass particles and to deposit the material layer by layer following a desired geometry. Controlled thermal input and cooling rate by fine tuning of the processing parameters allowed the production of crack-free fully dense implants. Microstructural characterization revealed chemical composition stability, but crystallization during processing was extensive when 45S5 bioactive glass was used. Improved results were obtained using the S520 bioactive glass, which showed limited surface crystallization due to an expanded sintering window (the difference between the glass transition temperature and crystallization onset temperature). Ion release from the S520 implants in Tris buffer was similar to that of amorphous 45S5 bioactive glass prepared by casting in graphite moulds. Laser processed S520 scaffolds were not cytotoxic in vitro when osteoblast-like MC3T3-E1 cells were cultured with the dissolution products of the glasses; and the MC3T3-E1 cells attached and spread well when cultured on the surface of the materials. Copyright © 2011 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  17. Rapid prototyping of microbial cell factories via genome-scale engineering.

    Science.gov (United States)

    Si, Tong; Xiao, Han; Zhao, Huimin

    2015-11-15

    Advances in reading, writing and editing genetic materials have greatly expanded our ability to reprogram biological systems at the resolution of a single nucleotide and on the scale of a whole genome. Such capacity has greatly accelerated the cycles of design, build and test to engineer microbes for efficient synthesis of fuels, chemicals and drugs. In this review, we summarize the emerging technologies that have been applied, or are potentially useful for genome-scale engineering in microbial systems. We will focus on the development of high-throughput methodologies, which may accelerate the prototyping of microbial cell factories. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Novel combination of reverse engineering and vapid prototyping in medicine

    CSIR Research Space (South Africa)

    Schenker, R

    1999-08-01

    Full Text Available The technologies of reverse engineering and rapid prototyping are emerging as useful new tools in medicine. One application is of particular interest in orthopaedic, dental and reconstructive surgery. It involves the imaging, modelling...

  19. Rapid Industrial Prototyping and SoC Design of 3G/4G Wireless Systems Using an HLS Methodology

    Directory of Open Access Journals (Sweden)

    Andres Takach

    2006-07-01

    Full Text Available Many very-high-complexity signal processing algorithms are required in future wireless systems, giving tremendous challenges to real-time implementations. In this paper, we present our industrial rapid prototyping experiences on 3G/4G wireless systems using advanced signal processing algorithms in MIMO-CDMA and MIMO-OFDM systems. Core system design issues are studied and advanced receiver algorithms suitable for implementation are proposed for synchronization, MIMO equalization, and detection. We then present VLSI-oriented complexity reduction schemes and demonstrate how to interact these high-complexity algorithms with an HLS-based methodology for extensive design space exploration. This is achieved by abstracting the main effort from hardware iterations to the algorithmic C/C++ fixed-point design. We also analyze the advantages and limitations of the methodology. Our industrial design experience demonstrates that it is possible to enable an extensive architectural analysis in a short-time frame using HLS methodology, which significantly shortens the time to market for wireless systems.

  20. Rapid Industrial Prototyping and SoC Design of 3G/4G Wireless Systems Using an HLS Methodology

    Directory of Open Access Journals (Sweden)

    Cavallaro JosephR

    2006-01-01

    Full Text Available Many very-high-complexity signal processing algorithms are required in future wireless systems, giving tremendous challenges to real-time implementations. In this paper, we present our industrial rapid prototyping experiences on 3G/4G wireless systems using advanced signal processing algorithms in MIMO-CDMA and MIMO-OFDM systems. Core system design issues are studied and advanced receiver algorithms suitable for implementation are proposed for synchronization, MIMO equalization, and detection. We then present VLSI-oriented complexity reduction schemes and demonstrate how to interact these high-complexity algorithms with an HLS-based methodology for extensive design space exploration. This is achieved by abstracting the main effort from hardware iterations to the algorithmic C/C++ fixed-point design. We also analyze the advantages and limitations of the methodology. Our industrial design experience demonstrates that it is possible to enable an extensive architectural analysis in a short-time frame using HLS methodology, which significantly shortens the time to market for wireless systems.

  1. A Computuerized Operator Support System Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Ken [Idaho National Lab. (INL), Idaho Falls, ID (United States); Boring, Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lew, Roger [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ulrich, Tom [Idaho National Lab. (INL), Idaho Falls, ID (United States); Villim, Richard [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2013-11-01

    A report was published by the Idaho National Laboratory in September of 2012, entitled Design to Achieve Fault Tolerance and Resilience, which described the benefits of automating operator actions for transients. The report identified situations in which providing additional automation in lieu of operator actions would be advantageous. It recognized that managing certain plant upsets is sometimes limited by the operator’s ability to quickly diagnose the fault and to take the needed actions in the time available. Undoubtedly, technology is underutilized in the nuclear power industry for operator assistance during plant faults and operating transients. In contrast, other industry sectors have amply demonstrated that various forms of operator advisory systems can enhance operator performance while maintaining the role and responsibility of the operator as the independent and ultimate decision-maker. A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. The COSS does not supplant the role of the operator, but rather provides rapid assessments, computations, and recommendations to reduce workload and augment operator judgment and decision-making during fast-moving, complex events. This project proposes a general model for a control room COSS that addresses a sequence of general tasks required to manage any plant upset: detection, validation, diagnosis, recommendation, monitoring, and recovery. The model serves as a framework for assembling a set of technologies that can be interrelated to assist with each of these tasks. A prototype COSS has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based

  2. A Computuerized Operator Support System Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Ken [Idaho National Lab. (INL), Idaho Falls, ID (United States); Boring, Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lew, Roger [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ulrich, Tom [Idaho National Lab. (INL), Idaho Falls, ID (United States); Villim, Richard [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2013-08-01

    A report was published by the Idaho National Laboratory in September of 2012, entitled Design to Achieve Fault Tolerance and Resilience, which described the benefits of automating operator actions for transients. The report identified situations in which providing additional automation in lieu of operator actions would be advantageous. It recognized that managing certain plant upsets is sometimes limited by the operator’s ability to quickly diagnose the fault and to take the needed actions in the time available. Undoubtedly, technology is underutilized in the nuclear power industry for operator assistance during plant faults and operating transients. In contrast, other industry sectors have amply demonstrated that various forms of operator advisory systems can enhance operator performance while maintaining the role and responsibility of the operator as the independent and ultimate decision-maker. A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. The COSS does not supplant the role of the operator, but rather provides rapid assessments, computations, and recommendations to reduce workload and augment operator judgment and decision-making during fast-moving, complex events. This project proposes a general model for a control room COSS that addresses a sequence of general tasks required to manage any plant upset: detection, validation, diagnosis, recommendation, monitoring, and recovery. The model serves as a framework for assembling a set of technologies that can be interrelated to assist with each of these tasks. A prototype COSS has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based

  3. Concept of data storage prototype for Super-C-Tau factory detector

    International Nuclear Information System (INIS)

    Maximov, D.A.

    2017-01-01

    The physics program of experiments at the Super- c τ factory with a peak luminosity of 10 35 cm −2 s −1 leads to high requrements for Data Acquisition and Data Storage systems. Detector data storage is one of the key component of the detector infrastructure, so it must be reliable, highly available and fault tolerant shared storage. It is mostly oriented (from end user point of view) for sequential but mixed read and write operations and is planed to store large data blocks (files). According to CDR of Super-C-Tau factory detector data storage must have very high performance (up to 1 Tbps in both directions simultaneously) and have significant volume (tens and hundreds of Petabytes). It is decided to build a series of prototypes with growing capabilities to investigate storage and neighboring technologies. First prototype of data storage is aimed to develop and test basic components of detector data storage system such as storage devices, networks and software. This prototype is designed to be capable to work with data rate of order 10 Gbps. It is estimated that about 5 modern computers with about 50 disks in total should be enough to archive required performance. The prototype will be based on Ceph storage technology. Ceph is a distributed storage system which allows to create storage solutions with very flexible design, high availability and scalability.

  4. Comparison of five-axis milling and rapid prototyping for implant surgical templates.

    Science.gov (United States)

    Park, Ji-Man; Yi, Tae-Kyoung; Koak, Jai-Young; Kim, Seong-Kyoon; Park, Eun-Jin; Heo, Seong-Joo

    2014-01-01

    This study aims to compare and evaluate the accuracy of surgical templates fabricated using coordinate synchronization processing with five-axis milling and design-related processing with rapid prototyping (RP). Master phantoms with 10 embedded gutta-percha cylinders hidden under artificial gingiva were fabricated and imaged using cone beam computed tomography. Vectors of the hidden cylinders were extracted and transferred to those of the planned implants through reverse engineering using virtual planning software. An RP-produced template was fabricated by stereolithography in photopolymer at the RP center according to planned data. Metal sleeves were bonded after holes were bored (group RP). For the milled template, milling coordinates were synchronized using the conversion process for the coordinate synchronization platform located on the model's bottom. Metal bushings were set on holes milled on the five-axis milling machine, on which the model was fixed through the coordinate synchronization plate, and the framework was constructed on the model using orthodontic resin (group CS). A computed tomography image was taken with templates firmly fixed on models using anchor pins (RP) or anchor screws (CS). The accuracy was analyzed via reverse engineering. Differences between the two groups were compared by repeated measures two-factor analysis. From the reverse-engineered image of the template on the experimental model, RP-produced templates showed significantly larger deviations than did milled surgical guides. Maximum deviations of the group RP were 1.58 mm (horizontal), 1.68 mm (vertical), and 8.51 degrees (angular); those of the group CS were 0.68 mm (horizontal), 0.41 mm (vertical), and 3.23 degrees (angular). A comparison of milling and RP template production methods showed that a vector-milled surgical guide had significantly smaller deviations than did an RP-produced template. The accuracy of computer-guided milled surgical templates was within the safety

  5. A comparative study of wire feeding and powder feeding in direct diode laser deposition for rapid prototyping

    Energy Technology Data Exchange (ETDEWEB)

    Syed, Waheed Ul Haq [Laser Processing Research Centre, School of Mechanical Aerospace and Civil Engineering, Sackville Street Building, University of Manchester, P.O. Box 88, Manchester M60 1QD (United Kingdom)]. E-mail: w.syed@postgrad.manchester.ac.uk; Pinkerton, Andrew J. [Laser Processing Research Centre, School of Mechanical Aerospace and Civil Engineering, Sackville Street Building, University of Manchester, P.O. Box 88, Manchester M60 1QD (United Kingdom); Li Lin [Laser Processing Research Centre, School of Mechanical Aerospace and Civil Engineering, Sackville Street Building, University of Manchester, P.O. Box 88, Manchester M60 1QD (United Kingdom)

    2005-07-15

    Metal powder feeding has been used widely in various rapid prototyping and tooling processes such as direct laser deposition (DLD) and layered engineered net shaping (LENS) to achieve near net shape accuracy. Although powder recycling has been practiced, the material usage efficiency has been very low (normally below 30%). This study compares the process characteristics, advantages and disadvantages of wire- and powder-feed DLD. A 1.5 kW diode laser is used to build multiple layer parts, which are compared and analysed in terms of surface finish, microstructure and deposition efficiency. Scanning electron microscopy (SEM), X-ray diffraction and optical microscopy are used for the material characterisation. The microstructure of samples from both the methods is similar, with some porosity found in powder-feed components, but the surface finish and material usage efficiency is better for wire-feed samples. The deposition angle is found to be critical in the case of wire feeding and the characteristics of different feed angles are explored. Possible reasons for the different characteristics of the two deposition techniques are discussed.

  6. Diurnal evolution of wind structure and data availability measured by the DOE prototype radar system

    Science.gov (United States)

    Hirth, Brian D.; Schroeder, John L.; Guynes, Jerry G.

    2017-11-01

    A new Doppler radar prototype has been developed and deployed at Texas Tech University with a focus on enhancing the technologies’ capability to contribute to wind plant relevant complex flow measurements. In particular, improvements in data availability, total data coverage, and autonomous operation were targeted to enable contributions to a wider range of wind energy applications. Doppler radar offers rapid scan speeds, extended maximum range and excellent along-beam range resolution allowing for the simultaneous measurement of various wind phenomena ranging from regional and wind plant scales to inflow and wake flow assessment for an individual turbine. Data examples and performance improvements relative to a previous edition of the technology are presented, including insights into the influence of diurnal atmospheric stability evolution of wind structure and system performance.

  7. Design of Lightweight e Attendance Prototype Using Raspberry Pi

    International Nuclear Information System (INIS)

    Mohd Dzul Aiman Aslan; Mohamad Safuan Sulaiman; Saaidi Ismail; Mohd Fauzi Haris; Nurbahyah Hamdan; Abdul Muin Abd Rahman

    2014-01-01

    E-Attendance is a system that has been extensively used to record attendance in most of the official ceremony of Nuclear Malaysia. Currently, a computer is used as the client to record the input from the proximity card. However, further study on Raspberry Pi, the single board computer that use system on a chip (SoC) in the current market, discover that it is capable of delivering a simple light task of the e-attendance. With a compact memory and in linux environment, a prototype for lightweight e-attendance is being developed. This prototype of Raspberry Pi is believe to have potential in computer based system of Nuclear Technology such as access control, monitoring system and even robotic assistance. This paper will discuss the design of the prototype that resemble e-attendance to improve the robustness of the system. (author)

  8. Prototype Development Capabilities of 3D Spatial Interactions and Failures During Scenario Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Steven Prescott; Ramprasad Sampath; Curtis Smith; Tony Koonce

    2014-09-01

    Computers have been used for 3D modeling and simulation, but only recently have computational resources been able to give realistic results in a reasonable time frame for large complex models. This report addressed the methods, techniques, and resources used to develop a prototype for using 3D modeling and simulation engine to improve risk analysis and evaluate reactor structures and components for a given scenario. The simulations done for this evaluation were focused on external events, specifically tsunami floods, for a hypothetical nuclear power facility on a coastline.

  9. Microcatheter Shaping for Intracranial Aneurysm Coiling Using the 3-Dimensional Printing Rapid Prototyping Technology: Preliminary Result in the First 10 Consecutive Cases.

    Science.gov (United States)

    Namba, Katsunari; Higaki, Ayuho; Kaneko, Naoki; Mashiko, Toshihiro; Nemoto, Shigeru; Watanabe, Eiju

    2015-07-01

    An optimal microcatheter is necessary for successful coiling of an intracranial aneurysm. The optimal shape may be predetermined before the endovascular surgery via the use of a 3-dimensional (3D) printing rapid prototyping technology. We report a preliminary series of intracranial aneurysms treated with a microcatheter shape determined by the patient's anatomy and configuration of the aneurysm, which was fabricated with a 3D printer aneurysm model. A solid aneurysm model was fabricated with a 3D printer based on the data acquired from the 3D rotational angiogram. A hollow aneurysm model with an identical vessel and aneurysm lumen to the actual anatomy was constructed with use of the solid model as a mold. With use of the solid model, a microcatheter shaping mandrel was formed to identically line the 3D curvature of the parent vessel and the long axis of the aneurysm. With use of the mandrel, a test microcatheter was shaped and validated for the accuracy with the hollow model. All the planning processes were undertaken at least 1 day before treatment. The preshaped mandrel was then applied in the endovascular procedure. Ten consecutive intracranial aneurysms were coiled with the pre-planned shape of the microcatheter and evaluated for the clinical and anatomical outcomes and microcatheter accuracy and stability. All of pre-planned microcatheters matched the vessel and aneurysm anatomy. Seven required no microguidewire assistance in catheterizing the aneurysm whereas 3 required guiding of a microguidewire. All of the microcatheters accurately aligned the long axis of the aneurysm. The pre-planned microcatheter shapes demonstrated stability in all except in 1 large aneurysm case. When a 3D printing rapid type prototyping technology is used, a patient-specific and optimal microcatheter shape may be determined preoperatively. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Characterization of a Reconfigurable Free-Space Optical Channel for Embedded Computer Applications with Experimental Validation Using Rapid Prototyping Technology

    Directory of Open Access Journals (Sweden)

    Rafael Gil-Otero

    2007-02-01

    Full Text Available Free-space optical interconnects (FSOIs are widely seen as a potential solution to current and future bandwidth bottlenecks for parallel processors. In this paper, an FSOI system called optical highway (OH is proposed. The OH uses polarizing beam splitter-liquid crystal plate (PBS/LC assemblies to perform reconfigurable beam combination functions. The properties of the OH make it suitable for embedding complex network topologies such as completed connected mesh or hypercube. This paper proposes the use of rapid prototyping technology for implementing an optomechanical system suitable for studying the reconfigurable characteristics of a free-space optical channel. Additionally, it reports how the limited contrast ratio of the optical components can affect the attenuation of the optical signal and the crosstalk caused by misdirected signals. Different techniques are also proposed in order to increase the optical modulation amplitude (OMA of the system.

  11. Characterization of a Reconfigurable Free-Space Optical Channel for Embedded Computer Applications with Experimental Validation Using Rapid Prototyping Technology

    Directory of Open Access Journals (Sweden)

    Lim Theodore

    2007-01-01

    Full Text Available Free-space optical interconnects (FSOIs are widely seen as a potential solution to current and future bandwidth bottlenecks for parallel processors. In this paper, an FSOI system called optical highway (OH is proposed. The OH uses polarizing beam splitter-liquid crystal plate (PBS/LC assemblies to perform reconfigurable beam combination functions. The properties of the OH make it suitable for embedding complex network topologies such as completed connected mesh or hypercube. This paper proposes the use of rapid prototyping technology for implementing an optomechanical system suitable for studying the reconfigurable characteristics of a free-space optical channel. Additionally, it reports how the limited contrast ratio of the optical components can affect the attenuation of the optical signal and the crosstalk caused by misdirected signals. Different techniques are also proposed in order to increase the optical modulation amplitude (OMA of the system.

  12. Acquisition and manipulation of computed tomography images of the maxillofacial region for biomedical prototyping

    International Nuclear Information System (INIS)

    Meurer, Maria Ines; Silva, Jorge Vicente Lopes da; Santa Barbara, Ailton; Nobre, Luiz Felipe; Oliveira, Marilia Gerhardt de; Silva, Daniela Nascimento

    2008-01-01

    Biomedical prototyping has resulted from a merger of rapid prototyping and imaging diagnosis technologies. However, this process is complex, considering the necessity of interaction between biomedical sciences and engineering. Good results are highly dependent on the acquisition of computed tomography images and their subsequent manipulation by means of specific software. The present study describes the experience of a multidisciplinary group of researchers in the acquisition and manipulation of computed tomography images of the maxillofacial region aiming at biomedical prototyping for surgical purposes. (author)

  13. Organisational Capability--What Does It Mean?

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2006

    2006-01-01

    Organisational capability is rapidly becoming recognized as the key to organizational success. However, the lack of research on it has been well documented in the literature, and organizational capability remains an elusive concept. Yet an understanding of organizational capability can offer insights into how RTOs might work most effectively,…

  14. Rapid die manufacturing using direct laser metal deposition

    CSIR Research Space (South Africa)

    Pereira, MFVT

    2009-01-01

    Full Text Available This paper highlights the work undertaken at the CSIR on the issue of rapid die manufacturing through the application and evaluation of a rapid prototyping technique and coating technologies applied to die components of a high pressure casting die...

  15. Use of artificial intelligence techniques for visual inspection systems prototyping. Application to magnetoscopy

    International Nuclear Information System (INIS)

    Pallas, Christophe

    1987-01-01

    The automation of visual inspection is a complex task that requires collaboration between experts, for example inspection specialist, vision specialist. on-line operators. Solving such problems through prototyping promotes this collaboration: the use of a non specific programming environment allows rapid, concrete checking of method validity, thus leading incrementally to the final system. In this context, artificial intelligence techniques permit easy, extensible, and modular design of the prototype, together with heuristic solution building. We define and achieve the SPOR prototyping environment, based on object-oriented programming and rules-basis managing. The feasibility and the validity of an heuristic method for automated visual inspection in fluoroscopy have been proved through prototyping in SPOR. (author) [fr

  16. Recognizing human actions by learning and matching shape-motion prototype trees.

    Science.gov (United States)

    Jiang, Zhuolin; Lin, Zhe; Davis, Larry S

    2012-03-01

    A shape-motion prototype-based approach is introduced for action recognition. The approach represents an action as a sequence of prototypes for efficient and flexible action matching in long video sequences. During training, an action prototype tree is learned in a joint shape and motion space via hierarchical K-means clustering and each training sequence is represented as a labeled prototype sequence; then a look-up table of prototype-to-prototype distances is generated. During testing, based on a joint probability model of the actor location and action prototype, the actor is tracked while a frame-to-prototype correspondence is established by maximizing the joint probability, which is efficiently performed by searching the learned prototype tree; then actions are recognized using dynamic prototype sequence matching. Distance measures used for sequence matching are rapidly obtained by look-up table indexing, which is an order of magnitude faster than brute-force computation of frame-to-frame distances. Our approach enables robust action matching in challenging situations (such as moving cameras, dynamic backgrounds) and allows automatic alignment of action sequences. Experimental results demonstrate that our approach achieves recognition rates of 92.86 percent on a large gesture data set (with dynamic backgrounds), 100 percent on the Weizmann action data set, 95.77 percent on the KTH action data set, 88 percent on the UCF sports data set, and 87.27 percent on the CMU action data set.

  17. SIMS prototype system 4: Design data brochure

    Science.gov (United States)

    1978-01-01

    A pre-package prototype unit having domestic hot water and room solar heating capability that uses air as the collector fluid is described. This system is designed to be used with a small single-family dwelling where a roof mounted collector array is not feasible. The prototype unit is an assemble containing 203 square feet of effective collector surface with 113 cubic feet of rock storage. The design of structure and storage is modular, which permits expansion and reduction of the collector array and storage bed in 68 square feet and 37 cubic feet increments respectively. The system is designed to be transportable. This permitted assemble and certification testing in one area and installation in another area without tear down and reassemble. Design, installation, operation, performance and maintenance of this system are described.

  18. First Results of an “Artificial Retina” Processor Prototype

    International Nuclear Information System (INIS)

    Cenci, Riccardo; Bedeschi, Franco; Marino, Pietro; Morello, Michael J.; Ninci, Daniele; Piucci, Alessio; Punzi, Giovanni; Ristori, Luciano; Spinella, Franco; Stracka, Simone; Tonelli, Diego; Walsh, John

    2016-01-01

    We report on the performance of a specialized processor capable of reconstructing charged particle tracks in a realistic LHC silicon tracker detector, at the same speed of the readout and with sub-microsecond latency. The processor is based on an innovative pattern-recognition algorithm, called “artificial retina algorithm”, inspired from the vision system of mammals. A prototype of the processor has been designed, simulated, and implemented on Tel62 boards equipped with high-bandwidth Altera Stratix III FPGA devices. The prototype is the first step towards a real-time track reconstruction device aimed at processing complex events of high-luminosity LHC experiments at 40 MHz crossing rate

  19. Characterisation and Control of a Prototype HTS SMES Device

    International Nuclear Information System (INIS)

    Hawley, C J; Cuiuri, D; Cook, C D; Gower, S A; Beales, T P

    2006-01-01

    A 2.79 kJ prototype high transition temperature Superconducting Magnetic Energy Storage (SMES) device has been constructed. The coil for the prototype has been wound using High Temperature Superconducting (HTS) BSCCO-2223 tape. The refrigeration system is a gaseous helium cold head cryocooler used to maintain the SMES coil at a temperature of 30 K, improving the I c characteristic of the coil by a factor of 4.7 compared to that at 77 K. The SMES device is capable of supplying a 3-phase load during power interruptions, and has been constructed during a program to develop a larger 20 kJ system aimed at industrial applications

  20. Hanford beta-gamma personnel dosimeter prototypes and evaluation

    International Nuclear Information System (INIS)

    Fix, J.J.; Holbrook, K.L.; Soldat, K.L.

    1983-04-01

    Upgraded and modified Hanford dosimeter prototypes were evaluated for possible use at Hanford as a primary beta-gamma dosimeter. All prototypes were compatible with the current dosimeter card and holder design, as well as processing with the automated Hanford readers. Shallow- and deep-dose response was determined for selected prototypes using several beta sources, K-fluorescent x rays and filtered x-ray techniques. All prototypes included a neutron sensitive chip. A progressive evaluation of the performance of each of the upgrades to the current dosimeter is described. In general, the performance of the current dosimeter can be upgraded using individual chip sensitivity factors to improve precision and an improved algorithm to minimize bias. The performance of this dosimeter would be adequate to pass all categories of the ANSI N13.11 performance criteria for dosimeter procesors, provided calibration techniques compatible with irradiations adopted in the standard were conducted. The existing neutron capability of the dosimeter could be retained. Better dosimeter performance to beta-gamma radiation can be achieved by modifying the Hanford dosimeter so that four of the five chip positions are devoted to calculating these doses instead of the currently used two chip positions. A neutron sensitive chip was used in the 5th chip position, but all modified dosimeter prototypes would be incapable of discriminating between thermal and epithermal neutrons. An improved low energy beta response can be achieved for the current dosimeter and all prototypes considered by eliminating the security credential. Further improvement can be obtained by incorporating the 15-mil thick TLD-700 chips

  1. Characterization of rapidly-prototyped, battery-operated, argon-hydrogen microplasma on a hybrid chip for elemental analysis of microsamples by portable optical emission spectrometry

    International Nuclear Information System (INIS)

    Weagant, Scott; Dulai, Gurjit; Li, Lu; Karanassios, Vassili

    2015-01-01

    A rapidly-prototyped, battery-operated, atmospheric-pressure, self-igniting Ar-H 2 microplasma was interfaced to a portable fiber-optic spectrometer. The microplasma-spectrometer combination was used to document the spectral lines emitted when μL of dilute solutions of single element standards of Ag, Ba, Ca, Eu, Pd, Rb and Sr were first dried and then vaporized into the microplasma. A small-size, electrothermal vaporization system was used for microsample introduction. Identification of the prominent spectral lines for these elements is reported. It was found that the most prominent spectral line for Ba, Ca and Sr was different than that emitted from an inductively coupled plasma (ICP). In general, prominent spectral lines with low excitation energy were dominating, thus resulting in spectra simpler than those emitted from an ICP. Detection limits were between 45 and 180 pg (expressed in absolute amounts). When expressed in relative concentration units, they ranged between 15 and 60 μg/L (obtained using 3 μL diluted standards). Calibration curves were linear (on the average) for 1.5 orders-of-magnitude. Average precision was 15%. Analytical capability and utility was demonstrated using the determination of Ca and Mg in (medicinal) thermal spring water. - Highlights: • Microplasma emission spectra for Ag, Ba, Ca, Eu, Pd, Rb and Sr are reported. • Absolute amount detection limits ranged between 45 pg and 180 pg. • Relative unit detection limits ranged between 15 and 60 μg/L (using 3 μL). • The effect of vaporization temperature on analyte signals is reported. • Ca and Mg concentrations in (medicinal) thermal spring water were determined

  2. Characterization of rapidly-prototyped, battery-operated, argon-hydrogen microplasma on a hybrid chip for elemental analysis of microsamples by portable optical emission spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Weagant, Scott; Dulai, Gurjit; Li, Lu; Karanassios, Vassili, E-mail: vkaranassios@uwaterloo.ca

    2015-04-01

    A rapidly-prototyped, battery-operated, atmospheric-pressure, self-igniting Ar-H{sub 2} microplasma was interfaced to a portable fiber-optic spectrometer. The microplasma-spectrometer combination was used to document the spectral lines emitted when μL of dilute solutions of single element standards of Ag, Ba, Ca, Eu, Pd, Rb and Sr were first dried and then vaporized into the microplasma. A small-size, electrothermal vaporization system was used for microsample introduction. Identification of the prominent spectral lines for these elements is reported. It was found that the most prominent spectral line for Ba, Ca and Sr was different than that emitted from an inductively coupled plasma (ICP). In general, prominent spectral lines with low excitation energy were dominating, thus resulting in spectra simpler than those emitted from an ICP. Detection limits were between 45 and 180 pg (expressed in absolute amounts). When expressed in relative concentration units, they ranged between 15 and 60 μg/L (obtained using 3 μL diluted standards). Calibration curves were linear (on the average) for 1.5 orders-of-magnitude. Average precision was 15%. Analytical capability and utility was demonstrated using the determination of Ca and Mg in (medicinal) thermal spring water. - Highlights: • Microplasma emission spectra for Ag, Ba, Ca, Eu, Pd, Rb and Sr are reported. • Absolute amount detection limits ranged between 45 pg and 180 pg. • Relative unit detection limits ranged between 15 and 60 μg/L (using 3 μL). • The effect of vaporization temperature on analyte signals is reported. • Ca and Mg concentrations in (medicinal) thermal spring water were determined.

  3. Improvement of handle grip using reverse engineering, CAE and Rapid Prototyping

    Directory of Open Access Journals (Sweden)

    Stoklasek Pavel

    2016-01-01

    Full Text Available The overwhelming majority of manual operations is even nowadays performed by using manual hand tools. These tools can be divided into 2 groups – hand tools designed for general use or a single-purpose hand tools for special operations. Tool described in this paper is used in assembling operation in the completion of electric motor. During the design of the existing tools the requirements for a functional part of the tool (lifespan, inability to damage the engine installation were fully considered, demands for ergonomic grip area, however, were not taken into account. Long-term use of incorrectly designed tool causes carpal tunnel syndrome, hand-arm vibration syndrome, diminished sensitivity or tingling in the fingers of workers. These difficulties can be reduced or entirely eliminated due to proper design of the grip of hand tool. Most authors focus on adjusting the grip for optimum ergonomics at individual types of grips (cylindrical, palmar, lateral, etc.. However, as already mentioned, there are tools for specific operations when the working area is limited by space or a specific type of load on the grip is needed. In some cases, it is often necessary to change the type of grip or combine different types of grips. This paper describes the design of an optimal grip of hand tool used for specific operation when assembling motors. Design of prototype mold and production of functional prototypes for ergonomics assessment directly in the workplace were realized. New design of handle should reduce the risk primarily of developing carpal tunnel in long-term use.

  4. Prototyping a Global Soft X-Ray Imaging Instrument for Heliophysics, Planetary Science, and Astrophysics Science

    Science.gov (United States)

    Collier, M. R.; Porter, F. S.; Sibeck, D. G.; Carter, J. A.; Chiao, M. P.; Chornay, D. J.; Cravens, T.; Galeazzi, M.; Keller, J. W.; Koutroumpa, D.; hide

    2012-01-01

    We describe current progress in the development of a prototype wide field-of-view soft X-ray imager that employs Lobstereye optics and targets heliophysics, planetary, and astrophysics science. The prototype will provide proof-of-concept for a future flight instrument capable of imaging the entire dayside magnetosheath from outside the magnetosphere. Such an instrument was proposed for the ESA AXIOM mission.

  5. Prototyping a Global Soft X-ray Imaging Instrument for Heliophysics, Planetary Science, and Astrophysics Science

    Science.gov (United States)

    Collier, Michael R.; Porter, F. Scott; Sibeck, David G.; Carter, Jenny A.; Chiao, Meng P.; Chornay, Dennis J.; Cravens, Thomas; Galeazzi, Massimiliano; Keller, John W.; Koutroumpa, Dimitra; hide

    2012-01-01

    We describe current progress in the development of a prototype wide field-of-view soft X-ray imager that employs Lobster-eye optics and targets heliophysics, planetary, and astrophysics science. The prototype will provide proof-of-concept for a future flight instrument capable of imaging the entire dayside magnetosheath from outside the magnetosphere. Such an instrument was proposed for the FSA AXIOM mission

  6. Architectural prototyping

    DEFF Research Database (Denmark)

    Bardram, Jakob Eyvind; Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2004-01-01

    A major part of software architecture design is learning how specific architectural designs balance the concerns of stakeholders. We explore the notion of "architectural prototypes", correspondingly architectural prototyping, as a means of using executable prototypes to investigate stakeholders...

  7. Evaluation of the need for a rapid depressurization capability for Combustion Engineering plants

    International Nuclear Information System (INIS)

    Marsh, L.; Liang, C.

    1984-12-01

    This report documents the NRC staff evaluation of the need for providing a rapid primary system depressurization capability, in particular by using a power-operated relief valve(s) (PORVs), in the current 3410-MWt and 3800-MWt classes of plants designed by Combustion Engineering (CE). The staff reviewed the responses of licensees, applicants, and vendors to staff questions, supplemented by independent analyses by the staff and its contractors. The staff review led to the conclusion that, on the basis of risk reduction and cost/benefit considerations, no overwhelming benefit would result from requiring the installation of PORVs in CE plants that currently do not have them. However, when other unquantifiable considerations regarding the potential benefits of a PORV are factored into the evaluation, it appears that more substantial benefits could be realized. Given the more comprehensive studies currently under way to resolve the generic unresolved safety issue, USI A-45, Decay Heat Removal Reliability, the staff concludes that the decision regarding PORVs for these CE plants should be deferred and incorporated into the technical resolution of USI A-45

  8. Chest-wall reconstruction with a customized titanium-alloy prosthesis fabricated by 3D printing and rapid prototyping.

    Science.gov (United States)

    Wen, Xiaopeng; Gao, Shan; Feng, Jinteng; Li, Shuo; Gao, Rui; Zhang, Guangjian

    2018-01-08

    As 3D printing technology emerge, there is increasing demand for a more customizable implant in the repair of chest-wall bony defects. This article aims to present a custom design and fabrication method for repairing bony defects of the chest wall following tumour resection, which utilizes three-dimensional (3D) printing and rapid-prototyping technology. A 3D model of the bony defect was generated after acquiring helical CT data. A customized prosthesis was then designed using computer-aided design (CAD) and mirroring technology, and fabricated using titanium-alloy powder. The mechanical properties of the printed prosthesis were investigated using ANSYS software. The yield strength of the titanium-alloy prosthesis was 950 ± 14 MPa (mean ± SD), and its ultimate strength was 1005 ± 26 MPa. The 3D finite element analyses revealed that the equivalent stress distribution of each prosthesis was unifrom. The symmetry and reconstruction quality contour of the repaired chest wall was satisfactory. No rejection or infection occurred during the 6-month follow-up period. Chest-wall reconstruction with a customized titanium-alloy prosthesis is a reliable technique for repairing bony defects.

  9. Prototype Morphing Fan Nozzle Demonstrated

    Science.gov (United States)

    Lee, Ho-Jun; Song, Gang-Bing

    2004-01-01

    Ongoing research in NASA Glenn Research Center's Structural Mechanics and Dynamics Branch to develop smart materials technologies for aeropropulsion structural components has resulted in the design of the prototype morphing fan nozzle shown in the photograph. This prototype exploits the potential of smart materials to significantly improve the performance of existing aircraft engines by introducing new inherent capabilities for shape control, vibration damping, noise reduction, health monitoring, and flow manipulation. The novel design employs two different smart materials, a shape-memory alloy and magnetorheological fluids, to reduce the nozzle area by up to 30 percent. The prototype of the variable-area fan nozzle implements an overlapping spring leaf assembly to simplify the initial design and to provide ease of structural control. A single bundle of shape memory alloy wire actuators is used to reduce the nozzle geometry. The nozzle is subsequently held in the reduced-area configuration by using magnetorheological fluid brakes. This prototype uses the inherent advantages of shape memory alloys in providing large induced strains and of magnetorheological fluids in generating large resistive forces. In addition, the spring leaf design also functions as a return spring, once the magnetorheological fluid brakes are released, to help force the shape memory alloy wires to return to their original position. A computerized real-time control system uses the derivative-gain and proportional-gain algorithms to operate the system. This design represents a novel approach to the active control of high-bypass-ratio turbofan engines. Researchers have estimated that such engines will reduce thrust specific fuel consumption by 9 percent over that of fixed-geometry fan nozzles. This research was conducted under a cooperative agreement (NCC3-839) at the University of Akron.

  10. Using A Normative Framework to Explore the Prototyping of Wireless Grids

    DEFF Research Database (Denmark)

    Balke, Tina; De Vos, Marina; Padget, Julian

    2011-01-01

    The capacity for normative frameworks to capture the essential features of interactions between components in open architectures suggests they might also be of assistance in an early, rapid prototyping phase of system development, helping to refine concepts, identify actors, explore policies...

  11. An investigation of the potential of rapid prototyping technology for image‐guided surgery

    Science.gov (United States)

    Rajon, Didier A.; Bova, Frank J.; Bhasin, R. Rick; Friedman, William A.

    2006-01-01

    Image‐guided surgery can be broken down into two broad categories: frame‐based guidance and frameless guidance. In order to reduce both the invasive nature of stereotactic guidance and the cost in equipment and time, we have developed a new guidance technique based on rapid prototyping (RP) technology. This new system first builds a computer model of the patient anatomy and then fabricates a physical reference frame that provides a precise and unique fit to the patient anatomy. This frame incorporates a means of guiding the surgeon along a preplanned surgical trajectory. This process involves (1) obtaining a high‐resolution CT or MR scan, (2) building a computer model of the region of interest, (3) developing a surgical plan and physical guide, (4) designing a frame with a unique fit to the patient's anatomy with a physical linkage to the surgical guide, and (5) fabricating the frame using an RP unit. Software was developed to support these processes. To test the accuracy of this process, we first scanned and reproduced a plastic phantom fabricated to validate the system's ability to build an accurate virtual model. A target on the phantom was then identified, a surgical approach planned, a surgical guide designed, and the accuracy and precision of guiding a probe to that target were determined. Steps 1 through 5 were also evaluated using a head phantom. The results show that the RP technology can replicate an object from CT scans with submillimeter resolution. The fabricated reference frames, when positioned on the surface of the phantom and used to guide a surgical probe, can position the probe tip with an accuracy of 1.7 mm at the probe tip. These results demonstrate that the RP technology can be used for the fabrication of customized positioning frames for use in image‐guided surgery. PACS number: 87.57.Gg PMID:17533357

  12. RIA testing capability of the transient reactor test facility

    International Nuclear Information System (INIS)

    Crawford, D.C.; Swanson, R.W.

    1999-01-01

    The advent of high-burnup fuel implementation in LWRs has generated international interest in high-burnup LWR fuel performance. Recent testing under simulated RIA conditions has demonstrated that certain fuel designs fail at peak fuel enthalpy values that are below existing regulatory criteria. Because many of these tests were performed with non-prototypically aggressive test conditions (i.e., with power pulse widths less than 10 msec FWHM and with non-protoypic coolant configurations), the results (although very informative) do not indisputably identify failure thresholds and fuel behavior. The capability of the TREAT facility to perform simulated RIA tests with prototypic test conditions is currently being evaluated by ANL personnel. TREAT was designed to accommodate test loops and vehicles installed for in-pile transient testing. During 40 years of TREAT operation and fuel testing and evaluation, experimenters have been able to demonstrate and determine the transient behavior of several types of fuel under a variety of test conditions. This experience led to an evolution of test methodology and techniques which can be employed to assess RIA behavior of LWR fuel. A pressurized water loop that will accommodate RIA testing of LWR and CANDU-type fuel has completed conceptual design. Preliminary calculations of transient characteristics and energy deposition into test rods during hypothetical TREAT RIA tests indicate that with the installation of a pressurized water loop, the facility is quite capable of performing prototypic RIA testing. Typical test scenarios indicate that a simulated RIA with a 72 msec FWHM pulse width and energy deposition of 1200 kJ/kg (290 cal/gm) is possible. Further control system enhancements would expand the capability to pulse widths as narrow as 40 msec. (author)

  13. Rapid and Accurate Assembly Method for a New Laue Lens Prototype

    DEFF Research Database (Denmark)

    Wade, Colin; Barriere, Nicolas; Hanlon, Lorraine

    2015-01-01

    The Laue lens is a technology for gamma-ray astrophysics whereby gamma-rays of particular energies can be focused by a suitable arrangement of crystals. The Laue lens assembly station at UC Berkeley was used to build a technological demonstrator addressing the key issues of crystal mounting speed......, crystal position and orientation accuracy, and crystal reflectivity. The new prototype is a lens segment containing a total of 48 5 x 5 mm2 crystals - 36 Iron and 12 Aluminium. The segment is composed of 8 partial rings, each of which is aligned to diffract an energy between 95 and 130 keV from a source...

  14. Fiscal 1997 report on the results of the international standardization R and D. Data format for rapid prototyping systems; 1997 nendo seika hokokusho kokusai hyojun soseigata kenkyu kaihatsu. Sekiso zokei system yo data format

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Concerning the rapid prototyping (RP) system use new RP format and the related software, the paper promoted the international standardization in consideration of relationships with an international standard, STEP. RP, which is a technology to rapidly prototype a solid body based on the three-dimensional CAD data, is used in various fields of product manufacture, medical field, etc., and is expected to further expand its field of application. In this R and D, an international version of the RP software system developed for domestic use was developed, and at the same time a software was trially manufactured so that the data on STEP/AP203/CC5 and CC6 can be delivered to the system. Moreover, a plan on new AIC51X as the STEP/AIC suitable for PR was studied. Relating to these results, the paper conducted the publicity work to the persons concerned in RP in the U.S. and Europe, and also explained those at ISO/TC184/SC4 (STEP Conference). The PR use interface enabling highly rapid and accurate data processing reached to a stage of the international commercialization, and at the same time the study items were materialized for proposal of the new STEP standards suitable for RP. 18 refs., 80 figs., 12 tabs.

  15. Prototyping Practice

    DEFF Research Database (Denmark)

    Ramsgaard Thomsen, Mette; Tamke, Martin

    2015-01-01

    This paper examines the role of the prototyping in digital architecture. During the past decade, a new research field has emerged exploring the digital technology’s impact on the way we think, design and build our environment. In this practice the prototype, the pavilion, installation or demonstr......This paper examines the role of the prototyping in digital architecture. During the past decade, a new research field has emerged exploring the digital technology’s impact on the way we think, design and build our environment. In this practice the prototype, the pavilion, installation...

  16. Human Adipose-Derived Stem Cells on Rapid Prototyped Three-Dimensional Hydroxyapatite/Beta-Tricalcium Phosphate Scaffold.

    Science.gov (United States)

    Canciani, Elena; Dellavia, Claudia; Ferreira, Lorena Maria; Giannasi, Chiara; Carmagnola, Daniela; Carrassi, Antonio; Brini, Anna Teresa

    2016-05-01

    In the study, we assess a rapid prototyped scaffold composed of 30/70 hydroxyapatite (HA) and beta-tricalcium-phosphate (β-TCP) loaded with human adipose-derived stem cells (hASCs) to determine cell proliferation, differentiation toward osteogenic lineage, adhesion and penetration on/into the scaffold.In this in vitro study, hASCs isolated from fat tissue discarded after plastic surgery were expanded, characterized, and then loaded onto the scaffold. Cells were tested for: viability assay (Alamar Blue at days 3, 7 and Live/Dead at day 32), differentiation index (alkaline phosphatase activity at day 14), scaffold adhesion (standard error of the mean analysis at days 5 and 18), and penetration (ground sections at day 32).All the hASC populations displayed stemness markers and the ability to differentiate toward adipogenic and osteogenic lineages.Cellular vitality increased between 3 and 7 days, and no inhibitory effect by HA/β-TCP was observed. Under osteogenic stimuli, scaffold increased alkaline phosphatase activity of +243% compared with undifferentiated samples. Human adipose-derived stem cells adhered on HA/β-TCP surface through citoplasmatic extensions that occupied the macropores and built networks among them. Human adipose derived stem cells were observed in the core of HA/β-TCP. The current combination of hASCs and HA/β-TCP scaffold provided encouraging results. If authors' data will be confirmed in preclinical models, the present engineering approach could represent an interesting tool in treating large bone defects.

  17. Modeling and prototyping of biometric systems using dataflow programming

    Science.gov (United States)

    Minakova, N.; Petrov, I.

    2018-01-01

    The development of biometric systems is one of the labor-intensive processes. Therefore, the creation and analysis of approaches and techniques is an urgent task at present. This article presents a technique of modeling and prototyping biometric systems based on dataflow programming. The technique includes three main stages: the development of functional blocks, the creation of a dataflow graph and the generation of a prototype. A specially developed software modeling environment that implements this technique is described. As an example of the use of this technique, an example of the implementation of the iris localization subsystem is demonstrated. A variant of modification of dataflow programming is suggested to solve the problem related to the undefined order of block activation. The main advantage of the presented technique is the ability to visually display and design the model of the biometric system, the rapid creation of a working prototype and the reuse of the previously developed functional blocks.

  18. Skull reconstruction after resection of bone tumors in a single surgical time by the association of the techniques of rapid prototyping and surgical navigation.

    Science.gov (United States)

    Anchieta, M V M; Salles, F A; Cassaro, B D; Quaresma, M M; Santos, B F O

    2016-10-01

    Presentation of a new cranioplasty technique employing a combination of two technologies: rapid prototyping and surgical navigation. This technique allows the reconstruction of the skull cap after the resection of a bone tumor in a single surgical time. The neurosurgeon plans the craniotomy previously on the EximiusMed software, compatible with the Eximius Surgical Navigator, both from the company Artis Tecnologia (Brazil). The navigator imports the planning and guides the surgeon during the craniotomy. The simulation of the bone fault allows the virtual reconstruction of the skull cap and the production of a personalized modelling mold using the Magics-Materialise (Belgium)-software. The mold and a replica of the bone fault are made by rapid prototyping by the company Artis Tecnologia (Brazil) and shipped under sterile conditions to the surgical center. The PMMA prosthesis is produced during the surgical act with the help of a hand press. The total time necessary for the planning and production of the modelling mold is four days. The precision of the mold is submillimetric and accurately reproduces the virtual reconstruction of the prosthesis. The production of the prosthesis during surgery takes until twenty minutes depending on the type of PMMA used. The modelling mold avoids contraction and dissipates the heat generated by the material's exothermic reaction in the polymerization phase. The craniectomy is performed with precision over the drawing made with the help of the Eximius Surgical Navigator, according to the planned measurements. The replica of the bone fault serves to evaluate the adaptation of the prosthesis as a support for the perforations and the placement of screws and fixation plates, as per the surgeon's discretion. This technique allows the adequate oncologic treatment associated with a satisfactory aesthetic result, with precision, in a single surgical time, reducing time and costs.

  19. Rapid isolation of a facultative anaerobic electrochemically active bacterium capable of oxidizing acetate for electrogenesis and azo dyes reduction.

    Science.gov (United States)

    Shen, Nan; Yuan, Shi-Jie; Wu, Chao; Cheng, Yuan-Yuan; Song, Xiang-Ning; Li, Wen-Wei; Tong, Zhong-Hua; Yu, Han-Qing

    2014-05-01

    In this study, 27 strains of electrochemically active bacteria (EAB) were rapidly isolated and their capabilities of extracellular electron transfer were identified using a photometric method based on WO3 nanoclusters. These strains caused color change of WO3 from white to blue in a 24-well agar plate within 40 h. Most of the isolated EAB strains belonged to the genera of Aeromonas and Shewanella. One isolate, Pantoea agglomerans S5-44, was identified as an EAB that can utilize acetate as the carbon source to produce electricity and reduce azo dyes under anaerobic conditions. The results confirmed the capability of P. agglomerans S5-44 for extracellular electron transfer. The isolation of this acetate-utilizing, facultative EBA reveals the metabolic diversity of environmental bacteria. Such strains have great potential for environmental applications, especially at interfaces of aerobic and anaerobic environments, where acetate is the main available carbon source.

  20. Application of computer-aided three-dimensional skull model with rapid prototyping technique in repair of zygomatico-orbito-maxillary complex fracture.

    Science.gov (United States)

    Li, Wei Zhong; Zhang, Mei Chao; Li, Shao Ping; Zhang, Lei Tao; Huang, Yu

    2009-06-01

    With the advent of CAD/CAM and rapid prototyping (RP), a technical revolution in oral and maxillofacial trauma was promoted to benefit treatment, repair of maxillofacial fractures and reconstruction of maxillofacial defects. For a patient with zygomatico-facial collapse deformity resulting from a zygomatico-orbito-maxillary complex (ZOMC) fracture, CT scan data were processed by using Mimics 10.0 for three-dimensional (3D) reconstruction. The reduction design was aided by 3D virtual imaging and the 3D skull model was reproduced using the RP technique. In line with the design by Mimics, presurgery was performed on the 3D skull model and the semi-coronal incision was taken for reduction of ZOMC fracture, based on the outcome from the presurgery. Postoperative CT and images revealed significantly modified zygomatic collapse and zygomatic arch rise and well-modified facial symmetry. The CAD/CAM and RP technique is a relatively useful tool that can assist surgeons with reconstruction of the maxillofacial skeleton, especially in repairs of ZOMC fracture.

  1. Prototype moving-ring reactor

    International Nuclear Information System (INIS)

    Smith, A.C. Jr.; Ashworth, C.P.; Abreu, K.E.

    1982-01-01

    We have completed a design of the Prototype Moving-Ring Reactor. The fusion fuel is confined in current-carrying rings of magnetically-field-reversed plasma (Compact Toroids). The plasma rings, formed by a coaxial plasma gun, undergo adiabatic magnetic compression to ignition temperature while they are being injected into the reactor's burner section. The cylindrical burner chamber is divided into three burn stations. Separator coils and a slight axial guide field gradient are used to shuttle the ignited toroids rapidly from one burn station to the next, pausing for 1/3 of the total burn time at each station. D-T- 3 He ice pellets refuel the rings at a rate which maintains constant radiated power

  2. Autotransplantation of immature third molars using a computer-aided rapid prototyping model: a report of 4 cases.

    Science.gov (United States)

    Jang, Ji-Hyun; Lee, Seung-Jong; Kim, Euiseong

    2013-11-01

    Autotransplantation of immature teeth can be an option for premature tooth loss in young patients as an alternative to immediately replacing teeth with fixed or implant-supported prostheses. The present case series reports 4 successful autotransplantation cases using computer-aided rapid prototyping (CARP) models with immature third molars. The compromised upper and lower molars (n = 4) of patients aged 15-21 years old were transplanted with third molars using CARP models. Postoperatively, the pulp vitality and the development of the roots were examined clinically and radiographically. The patient follow-up period was 2-7.5 years after surgery. The long-term follow-up showed that all of the transplants were asymptomatic and functional. Radiographic examination indicated that the apices developed continuously and the root length and thickness increased. The final follow-up examination revealed that all of the transplants kept the vitality, and the apices were fully developed with normal periodontal ligaments and trabecular bony patterns. Based on long-term follow-up observations, our 4 cases of autotransplantation of immature teeth using CARP models resulted in favorable prognoses. The CARP model assisted in minimizing the extraoral time and the possible Hertwig epithelial root sheath injury of the transplanted tooth. Copyright © 2013 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  3. Development of rapid, continuous calibration techniques and implementation as a prototype system for civil engineering materials evaluation

    International Nuclear Information System (INIS)

    Scott, M. L.; Gagarin, N.; Mekemson, J. R.; Chintakunta, S. R.

    2011-01-01

    Until recently, civil engineering material calibration data could only be obtained from material sample cores or via time consuming, stationary calibration measurements in a limited number of locations. Calibration data are used to determine material propagation velocities of electromagnetic waves in test materials for use in layer thickness measurements and subsurface imaging. Limitations these calibration methods impose have been a significant impediment to broader use of nondestructive evaluation methods such as ground-penetrating radar (GPR). In 2006, a new rapid, continuous calibration approach was designed using simulation software to address these measurement limitations during a Federal Highway Administration (FHWA) research and development effort. This continuous calibration method combines a digitally-synthesized step-frequency (SF)-GPR array and a data collection protocol sequence for the common midpoint (CMP) method. Modeling and laboratory test results for various data collection protocols and materials are presented in this paper. The continuous-CMP concept was finally implemented for FHWA in a prototype demonstration system called the Advanced Pavement Evaluation (APE) system in 2009. Data from the continuous-CMP protocol is processed using a semblance/coherency analysis to determine material propagation velocities. Continuously calibrated pavement thicknesses measured with the APE system in 2009 are presented. This method is efficient, accurate, and cost-effective.

  4. A new experimental carotid siphon aneurysm model in canine based on the MR angiography and rapid prototyping technology

    International Nuclear Information System (INIS)

    Xie Jian; Li Minghua; Tan Huaqiao; Zhu Yueqi; Hu Dingjun; Qiao Ruihua; Fan Chunhua

    2009-01-01

    Objective: The aim of the experiment is to make an intracranial aneurysm model in canine. Methods: A digital tube was made based on raw magnetic resonance images of the human intracranial carotid artery. Then 6 tubes were made in the 3D rapid prototyping machine and coated with silicone. Finally we isolated the common carotid arteries of 6 canines and made them go through the tubes and anastomosed them end-to-side to get the aneurysm model. Six stents were implanted after one week. Results: Six aneurysm models were successfully made in canines. The parent artery had similar geometry of the human carotid siphon. All the aneurysms and parent arteries were patent in one week's follow-up. One canine died of excessive anesthesia after stenting. Two vascular models kept patent in one month without stenosis. The other 3 had some stenosis on the bends of the vessel. Conclusions: The aneurysm model in the experiment has high flexibility and reliability. The model provides an effective tool for research and testing neurovascular devices. It's also a useful device to train the neuroradiologists and interventional physicians. (authors)

  5. Old dogs are great at new tricks: column stores for ir prototyping

    NARCIS (Netherlands)

    H.F. Mühleisen (Hannes); T. Samar (Thaer); J.J.P. Lin (Jimmy); A.P. de Vries (Arjen)

    2014-01-01

    htmlabstractWe make the suggestion that instead of implementing custom index structures and query evaluation algorithms, IR researchers should simply store document representations in a column-oriented relational database and implement ranking models using SQL. For rapid prototyping, this is

  6. A Distributed Control System Prototyping Environment to Support Control Room Modernization

    Energy Technology Data Exchange (ETDEWEB)

    Lew, Roger Thomas [Idaho National Lab. (INL), Idaho Falls, ID (United States); Boring, Ronald Laurids [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ulrich, Thomas Anthony [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-12-01

    Operators of critical processes, such as nuclear power production, must contend with highly complex systems, procedures, and regulations. Developing human-machine interfaces (HMIs) that better support operators is a high priority for ensuring the safe and reliable operation of critical processes. Human factors engineering (HFE) provides a rich and mature set of tools for evaluating the performance of HMIs, however the set of tools for developing and designing HMIs is still in its infancy. Here we propose a rapid prototyping approach for integrating proposed HMIs into their native environments before a design is finalized. This approach allows researchers and developers to test design ideas and eliminate design flaws prior to fully developing the new system. We illustrate this approach with four prototype designs developed using Microsoft’s Windows Presentation Foundation (WPF). One example is integrated into a microworld environment to test the functionality of the design and identify the optimal level of automation for a new system in a nuclear power plant. The other three examples are integrated into a full-scale, glasstop digital simulator of a nuclear power plant. One example demonstrates the capabilities of next generation control concepts; another aims to expand the current state of the art; lastly, an HMI prototype was developed as a test platform for a new control system currently in development at U.S. nuclear power plants. WPF possesses several characteristics that make it well suited to HMI design. It provides a tremendous amount of flexibility, agility, robustness, and extensibility. Distributed control system (DCS) specific environments tend to focus on the safety and reliability requirements for real-world interfaces and consequently have less emphasis on providing functionality to support novel interaction paradigms. Because of WPF’s large user-base, Microsoft can provide an extremely mature tool. Within process control applications,WPF is

  7. Design and prototyping of real-time systems using CSP and CML

    DEFF Research Database (Denmark)

    Rischel, Hans; Sun, Hong Yan

    1997-01-01

    A procedure for systematic design of event based systems is introduced by means of the Production Cell case study. The design is documented by CSP style processes, which allow both verification using formal techniques and also validation of a rapid prototype in the functional language CML...

  8. Development of a Decision Aid for Cardiopulmonary Resuscitation Involving Intensive Care Unit Patients' and Health Professionals' Participation Using User-Centered Design and a Wiki Platform for Rapid Prototyping: A Research Protocol

    Science.gov (United States)

    Heyland, Daren Keith; Ebell, Mark H; Dupuis, Audrey; Lavoie-Bérard, Carole-Anne; Légaré, France; Archambault, Patrick Michel

    2016-01-01

    Background Cardiopulmonary resuscitation (CPR) is an intervention used in cases of cardiac arrest to revive patients whose heart has stopped. Because cardiac arrest can have potentially devastating outcomes such as severe neurological deficits even if CPR is performed, patients must be involved in determining in advance if they want CPR in the case of an unexpected arrest. Shared decision making (SDM) facilitates discussions about goals of care regarding CPR in intensive care units (ICUs). Patient decision aids (DAs) are proven to support the implementation of SDM. Many patient DAs about CPR exist, but they are not universally implemented in ICUs in part due to lack of context and cultural adaptation. Adaptation to local context is an important phase of implementing any type of knowledge tool such as patient DAs. User-centered design supported by a wiki platform to perform rapid prototyping has previously been successful in creating knowledge tools adapted to the needs of patients and health professionals (eg, asthma action plans). This project aims to explore how user-centered design and a wiki platform can support the adaptation of an existing DA for CPR to the local context. Objective The primary objective is to use an existing DA about CPR to create a wiki-based DA that is adapted to the context of a single ICU and tailorable to individual patient’s risk factors while employing user-centered design. The secondary objective is to document the use of a wiki platform for the adaptation of patient DAs. Methods This study will be conducted in a mixed surgical and medical ICU at Hôtel-Dieu de Lévis, Quebec, Canada. We plan to involve all 5 intensivists and recruit at least 20 alert and oriented patients admitted to the ICU and their family members if available. In the first phase of this study, we will observe 3 weeks of daily interactions between patients, families, intensivists, and other allied health professionals. We will specifically observe 5 dyads of

  9. Digital Microdroplet Ejection Technology-Based Heterogeneous Objects Prototyping

    OpenAIRE

    Li, Na; Yang, Jiquan; Feng, Chunmei; Yang, Jianfei; Zhu, Liya; Guo, Aiqing

    2016-01-01

    An integrate fabrication framework is presented to build heterogeneous objects (HEO) using digital microdroplets injecting technology and rapid prototyping. The heterogeneous materials part design and manufacturing method in structure and material was used to change the traditional process. The net node method was used for digital modeling that can configure multimaterials in time. The relationship of material, color, and jetting nozzle was built. The main important contributions are to combi...

  10. Rapid Prototyping by Single Point Incremental Forming of Sheet Metal

    DEFF Research Database (Denmark)

    Skjødt, Martin

    2008-01-01

    . The process is incremental forming since plastic deformation takes place in a small local zone underneath the forming tool, i.e. the sheet is formed as a summation of the movement of the local plastic zone. The process is slow and therefore only suited for prototypes or small batch production. On the other...... in the plastic zone. Using these it is demonstrated that the growth rate of accumulated damage in SPIF is small compared to conventional sheet forming processes. This combined with an explanation why necking is suppressed is a new theory stating that SPIF is limited by fracture and not necking. The theory...... SPIF. A multi stage strategy is presented which allows forming of a cup with vertical sides in about half of the depth. It is demonstrated that this results in strain paths which are far from straight, but strains are still limited by a straight fracture line in the principal strain space. The multi...

  11. CONCEPTUAL PRODUCT DESIGN IN VIRTUAL PROTOTYPING

    Directory of Open Access Journals (Sweden)

    Debeleac Carmen

    2009-07-01

    Full Text Available A conceptual model of the industrial design process for isolation against vibrations is proposed and described. This model can be used to design products subject to functional, manufacturing, ergonomic, aesthetic constraints. In this paper, the main stages of the model, such as component organization, conception shape, product detailing and graphical design are discussed. The work has confirmed the validity of proposed model for rapid generation of aesthetic preliminary product designs using the virtual prototyping technique, by one of its main component that is conceptual product design.

  12. Enhancing experience prototyping by the help of mixed-fidelity prototypes

    OpenAIRE

    Yasar, Ansar-Ul-Haque

    2007-01-01

    In this research review I undertook the problem related to the usage of a new concept known as the Mixed- Fidelity Prototype which is a mixture of its predecessors Low- and High- Fidelity Prototypes in Experience Prototyping. Experience Prototyping is a good way to explore, communicate and interact with the designs we develop like experiencing cycling on the ice, although the mood, snow conditions, bicycle type and many other factors really matter and tend to change with time. Experience Prot...

  13. Design and evaluation of RaPIDO, a platform for rapid prototyping of interactive outdoor games

    NARCIS (Netherlands)

    Soute, I.; Vacaretu, T.; de Wit, J.; Markopoulos, P.

    Outdoor, multi-player games involving social interaction and physical activity are an emerging class of applications particularly interesting for children, for whom the attraction and the health and developmental benefits are clear cut. Implementing and prototyping such games present non-trivial

  14. A second generation 50 Mbps VLSI level zero processing system prototype

    Science.gov (United States)

    Harris, Jonathan C.; Shi, Jeff; Speciale, Nick; Bennett, Toby

    1994-01-01

    Level Zero Processing (LZP) generally refers to telemetry data processing functions performed at ground facilities to remove all communication artifacts from instrument data. These functions typically include frame synchronization, error detection and correction, packet reassembly and sorting, playback reversal, merging, time-ordering, overlap deletion, and production of annotated data sets. The Data Systems Technologies Division (DSTD) at Goddard Space Flight Center (GSFC) has been developing high-performance Very Large Scale Integration Level Zero Processing Systems (VLSI LZPS) since 1989. The first VLSI LZPS prototype demonstrated 20 Megabits per second (Mbp's) capability in 1992. With a new generation of high-density Application-specific Integrated Circuits (ASIC) and a Mass Storage System (MSS) based on the High-performance Parallel Peripheral Interface (HiPPI), a second prototype has been built that achieves full 50 Mbp's performance. This paper describes the second generation LZPS prototype based upon VLSI technologies.

  15. Advanced Process Chains for Prototyping and Pilot Production based on Additive Manufacturing

    DEFF Research Database (Denmark)

    Mischkot, Michael

    2015-01-01

    For many years, Additive Manufacturing (AM) has been a well-established production technology used mainly for rapid prototyping. But the need for increased flexibility and economic low volume production led to the discovery of Additive Manufacturing as a suitable fabrication technique (Mellor 2013...

  16. Development and Assessment of Planetary Gear Unit for Experimental Prototype of Vertical Axis Wind Turbine

    Directory of Open Access Journals (Sweden)

    Urbahs A.

    2017-10-01

    Full Text Available The theoretical calculation for development of planetary gear unit of wind turbine (WT and its experimental tests are presented in the paper. Development of experimental prototypes from composite materials is essential to determine capability of element and its impact on feature. Two experimental scale prototypes of planetary gear unit for WT were developed for such purposes. Hall transducer, servomechanisms and optical tachometers were used to obtain results, comparison analysis of theoretical and actual data was performed as well as quality assessment of experimental prototypes of planetary gear unit. After kinematic and load analysis as well as control of rotation frequency, it is possible to declare that the unit is able to operate at designated quality. Theoretical calculations and test results obtained are used for industrial WT prototype development.

  17. Development and Assessment of Planetary Gear Unit for Experimental Prototype of Vertical Axis Wind Turbine

    Science.gov (United States)

    Urbahs, A.; Urbaha, M.; Carjova, K.

    2017-10-01

    The theoretical calculation for development of planetary gear unit of wind turbine (WT) and its experimental tests are presented in the paper. Development of experimental prototypes from composite materials is essential to determine capability of element and its impact on feature. Two experimental scale prototypes of planetary gear unit for WT were developed for such purposes. Hall transducer, servomechanisms and optical tachometers were used to obtain results, comparison analysis of theoretical and actual data was performed as well as quality assessment of experimental prototypes of planetary gear unit. After kinematic and load analysis as well as control of rotation frequency, it is possible to declare that the unit is able to operate at designated quality. Theoretical calculations and test results obtained are used for industrial WT prototype development.

  18. Performance of a Highly Granular Scintillator-SiPM Based Hadron Calorimeter Prototype in Strong Magnetic Fields

    OpenAIRE

    Graf, Christian; collaboration, for the CALICE

    2017-01-01

    Within the CALICE collaboration, several concepts for the hadronic calorimeter of a future linear collider detector are studied. After having demonstrated the capabilities of the measurement methods in "physics prototypes", the focus now lies on improving their implementation in "engineering prototypes", that are scalable to the full linear collider detector. The Analog Hadron Calorimeter (AHCAL) concept is a sampling calorimeter of tungsten or steel absorber plates and plastic scintillator t...

  19. Prototype readout system for a multi Mpixels UV single-photon imaging detector capable of space flight operation

    Science.gov (United States)

    Seljak, A.; Cumming, H. S.; Varner, G.; Vallerga, J.; Raffanti, R.; Virta, V.

    2018-02-01

    Our collaboration works on the development of a large aperture, high resolution, UV single-photon imaging detector, funded through NASA's Strategic Astrophysics Technology (SAT) program. The detector uses a microchannel plate for charge multiplication, and orthogonal cross strip (XS) anodes for charge readout. Our target is to make an advancement in the technology readiness level (TRL), which enables real scale prototypes to be tested for future NASA missions. The baseline detector has an aperture of 50×50 mm and requires 160 low-noise charge-sensitive channels, in order to extrapolate the incoming photon position with a spatial resolution of about 20 μm FWHM. Technologies involving space flight require highly integrated electronic systems operating at very low power. We have designed two ASICs which enable the construction of such readout system. First, a charge sensitive amplifier (CSAv3) ASIC provides an equivalent noise charge (ENC) of around 600 e-, and a baseline gain of 10 mV/fC. The second, a Giga Sample per Second (GSPS) ASIC, called HalfGRAPH, is a 12-bit analog to digital converter. Its architecture is based on waveform sampling capacitor arrays and has about 8 μs of analog storage memory per channel. Both chips encapsulate 16 measurement channels. Using these chips, a small scale prototype readout system has been constructed on a FPGA Mezzanine Board (FMC), equipped with 32 measurement channels for system evaluation. We describe the construction of HalfGRAPH ASIC, detector's readout system concept and obtained results from the prototype system. As part of the space flight qualification, these chips were irradiated with a Cobalt gamma-ray source, to verify functional operation under ionizing radiation exposure.

  20. Refinement of Foam Backfill Technology for Expedient Airfield Damage Repair; Phase 2: Development of Prototype Foam Dispensing Equipment and Improved Tactics, Techniques and Procedures

    Science.gov (United States)

    2017-12-01

    ER D C TR -1 7- 14 U.S. Air Force Rapid Airfield Damage Repair Modernization Program Refinement of Foam Backfill Technology for...Backfill Technology for Expedient Airfield Damage Repair Phase II: Development of Prototype Foam Dispensing Equipment and Improved Tactics...procedures (TTPs) for rapid airfield damage repair (RADR) using foam backfill technology . Three different prototype foam dispensing systems were

  1. ΔOSI: a prototype microstrip dosimeter for characterization of medical radiotherapy and radiosurgery systems

    International Nuclear Information System (INIS)

    Redondo-Fernandez, I.; Buttar, C.; Walsh, S.; Manolopoulos, S.; Homer, J.M.; Young, S.; Conway, J.

    2006-01-01

    As the technology for medical radiotherapy and radiosurgery evolves, there is a growing need for dosimeters capable of measuring dose distributions on-line with submillimeter spatial resolution, both for facility commissioning and patient-related quality assurance. We have designed and built a high spatial resolution dosimeter based on silicon micro-strip technology for characterization of small radiotherapy and radiosurgery fields. The aim is to provide relative dosimetry measurement with film-like spatial resolution and to be able to resolve the temporal evolution. Following the description of the prototypes, first beam test results of a 250 μm pitch, 128 channels prototype with X-rays in a clinical 6 MV accelerator are presented. The device demonstrated good dosimetric capabilities when compared to reference measurements made with ionization chambers and agrees with radiographic film in the steep dose gradient region produced by the collimator edge

  2. Investigating the role of implicit prototypes in the prototype willingness model.

    Science.gov (United States)

    Howell, Jennifer L; Ratliff, Kate A

    2017-06-01

    One useful theory to predict health behavior is the prototype-willingness model (PWM), which posits that people are more willing to engage in behavior to the extent that they have a positive view of the prototypical person who performs that behavior. The goal of the present research is to test whether adding an implicit measure of prototype favorability might improve explanatory power in the PWM. Two studies examined whether implicit prototype favorability uniquely predicted White women's intentions to engage in healthy sun behavior over the next 3-6 months, and their willingness to engage in risky sun behavior, should the opportunity arise. The results suggested that implicit prototype favorability, particularly implicit prototypes of those who engage in risky UV-related behaviors, uniquely predicted intentions to engage in healthy sun behavior and willingness to engage in risky sun behavior in the PWM.

  3. Rapid Tooling for Functional Prototype of Metal Mold Processes Final Report CRADA No. TC-1032-98

    Energy Technology Data Exchange (ETDEWEB)

    Heestand, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jaskolski, T. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-10-16

    Production inserts for die-casting were generally fabricated from materials with sufficient strength and· good wear properties at casting temperatures for long life. Frequently tool steels were used and machining was done with a combination of. conventional and Electric Discharge Machining (EDM) with some handwork, an expensive and time consuming process, partilly for prototype work. We proposed electron beam physical vapor deposition (EBPVD) as a process for rapid fabrication of dies. Metals, ranging from low melting point to refractory metals (Ta, Mo, etc.), would be evaporated and deposited at high rates (-2mm/hr.). Alloys could be easily evaporated and deposited if their constituent vapor pressures were similar and with more difficulty if they were not. Of course, layering of different materials was possible if required for a specific application. For example, a hard surface layer followed by a tough steel and backed by a high thermal conductivity (possibly cooled) copper layer could be fabricated. Electron-beam deposits exhibited 100% density and lull strength when deposited at a substrate (mandrel) temperature that was a substantial fraction of the deposited material's melting point. There were several materials that could have the required high temperature properties and ease of fabrication required for such a mandrel. We had successfully used graphite, machined from free formed objects with a replicator, to produce aluminum-bronze test molds. There were several parting layer materials of interest, but the ideal material depended upon the specific application.

  4. Semi-automated delineation of breast cancer tumors and subsequent materialization using three-dimensional printing (rapid prototyping).

    Science.gov (United States)

    Schulz-Wendtland, Rüdiger; Harz, Markus; Meier-Meitinger, Martina; Brehm, Barbara; Wacker, Till; Hahn, Horst K; Wagner, Florian; Wittenberg, Thomas; Beckmann, Matthias W; Uder, Michael; Fasching, Peter A; Emons, Julius

    2017-03-01

    Three-dimensional (3D) printing has become widely available, and a few cases of its use in clinical practice have been described. The aim of this study was to explore facilities for the semi-automated delineation of breast cancer tumors and to assess the feasibility of 3D printing of breast cancer tumors. In a case series of five patients, different 3D imaging methods-magnetic resonance imaging (MRI), digital breast tomosynthesis (DBT), and 3D ultrasound-were used to capture 3D data for breast cancer tumors. The volumes of the breast tumors were calculated to assess the comparability of the breast tumor models, and the MRI information was used to render models on a commercially available 3D printer to materialize the tumors. The tumor volumes calculated from the different 3D methods appeared to be comparable. Tumor models with volumes between 325 mm 3 and 7,770 mm 3 were printed and compared with the models rendered from MRI. The materialization of the tumors reflected the computer models of them. 3D printing (rapid prototyping) appears to be feasible. Scenarios for the clinical use of the technology might include presenting the model to the surgeon to provide a better understanding of the tumor's spatial characteristics in the breast, in order to improve decision-making in relation to neoadjuvant chemotherapy or surgical approaches. J. Surg. Oncol. 2017;115:238-242. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  5. Technical comparison of the commercialized Racon model 21000 Portable, Reconfigurable Line Sensor (PRLS) and original Sandia/USAF prototype

    International Nuclear Information System (INIS)

    Blattman, D.A.

    1993-01-01

    The military has been moving from a global strategic response with fixed site asset protection to regional tactical response requirements. This change necessitates high security sensor systems that can be easily relocated and rapidly placed in operation by unskilled operators. The Portable, Reconfigurable Line Sensor (PRLS) was developed by Sandia National Laboratories with United States Air Force funding. Racon, Inc. is now commercializing the PRLS through a Cooperative Research and Development Agreement (CRDA) with the United States Air Force. The commercialized design of the new PRLS bi-static radar sensor benefits from the extensive field testing of the original Sandia/USAF-developed engineering prototype systems of the 1980s. Tests conducted in hot, cold, wind, rain, and snow conditions verified exceptional intruder detection capability, resistance to spoofing attempts, and insusceptibility to mutual interference and nuisance alarms caused by birds or small animals. The use of 1990's implementation technology combined with extensive testing information has resulted in significant product performance enhancements as well as cost savings. This paper compares technical features of the original Sandia/USAF prototypes with the new commercialized Racon model 21000 Portable, Reconfigurable Line Sensor. The PRLS advances the art of outdoor security to meet the Relocatable Sensor System (RSS) challenge of the 1990s

  6. Characterisation of pixel sensor prototypes for the ALICE ITS upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Reidt, Felix [CERN (Switzerland); Physikalisches Institut, Universitaet Heidelberg (Germany); Collaboration: ALICE-Collaboration

    2014-07-01

    ALICE is preparing a major upgrade of its experimental apparatus to be installed in the second long LHC shutdown (LS2) in the years 2018-2019. A key element of the upgrade is the replacement of the Inner Tracking System (ITS) deploying Monolithic Active Pixel Sensors (MAPS). The upgraded ITS will have a reduced material budget while increasing the pixel density and readout rate capabilities. The novel design leads to higher pointing and momentum resolution as well as a p{sub T} acceptance extended to lower values. The corresponding sensor prototypes were qualified in laboratory measurements and beam tests with respect to their radiation tolerance and detection efficiency. This talk summarises recent results on the characterisation of prototypes belonging to the ALPIDE family.

  7. Capabilities of Future Training Support Packages

    National Research Council Canada - National Science Library

    Burnside, Billy

    2004-01-01

    .... This report identifies and analyzes five key capabilities needed in future TSPs: rapid tailoring or modification, reach, simulated operating environment, performance measurement, and pretests/selection criteria...

  8. 2018 Ground Robotics Capabilities Conference and Exhibiton

    Science.gov (United States)

    2018-04-11

    visual environment capable • x2 long range target acquisition systems (Stabilized) ( 2G FLIR or 3G FLIR LRAS3) • Lethality: • x1 XM813 30mm remote...AND MILLER BALLROOMS 6 1:35 – 2:15 pm DEFENSE MOBILITY ENTERPRISE SINGLETON BALLROOM Tony Melita Executive Director, National Advanced Mobility ...LUNCH STERNBERG/HAZEL AND MILLER BALLROOMS 8 12:10 – 1:50 pm PANEL—PROTOTYPING SINGLETON BALLROOM Bill Thomasmeyer Consultant, National Advanced Mobility

  9. Advanced Manufacturing Technologies (AMT): Modular Rapidly Manufactured SmallSat

    Data.gov (United States)

    National Aeronautics and Space Administration — Utilize advanced manufacturing processes to design and fabricate a fully functional prototype flight model, with the goal of demonstrating rapid on-orbit assembly of...

  10. Accelerator Tests of the Prototype Energetic Heavy Ion Sensor (EHIS) for GOES-R

    Science.gov (United States)

    Connell, J. J.; Lopate, C.; McKibben, R. B.

    2010-12-01

    The Energetic Heavy Ion Sensor (EHIS) is part of the Space Environmental In-Situ Suite (SEISS) for the Geostationary Operational Environment Satellite series R (GOES-R) program. It will measure energetic protons from 10-200 MeV and ions through nickel (Z=28) with similar penetrating power. By use of an Angle Detecting Inclined Sensor (ADIS) system, EHIS achieves single element resolution with extensive on-board event processing. A prototype or "brass-board" instrument, fully functional but not intended for environmental testing, has been completed. In November of 2009, we exposed the prototype to protons at Massachusetts General Hospital (MGH) and in March of 2010, we exposed it to Ni primary and fragment beams at the National Superconducting Cyclotron Laboratory's (NSCL) Coupled Cyclotron Facility (CCF). In both cases, the instrument was rotated over a range of angles and a moving degrader spread the energy from full beam energy to zero energy. We will present results of these tests. These show an angular resolution for the prototype which results in a one sigma charge resolution of ~0.25 e at Ni. The prototype also demonstrated the capability for calculating the charge of 2500 events per second with its internal processor, accumulating those events in on-board charge histograms, and thus providing unprecedented statistics in high flux conditions. The EHIS represents a major advance in capabilities for operational space weather instruments while also providing data quality suitable for scientific research. The EHIS instrument development project was funded by NASA under contract NNG06HX01C.

  11. Rapid Prototyping by 3D Printing for Advanced Radio Communications at 80 GHz and Above

    DEFF Research Database (Denmark)

    Salazar, Adrian Ruiz; Rommel, Simon; Anufriyev, Eldar

    2016-01-01

    This paper discusses the potential of 3D printing for the manufacturing of spiral phase plates for the generation of radio vortex beams for advanced radio communications. The design and prototyping of a number of phase plates for communications at 80GHz with radio vortex beams is discussed...

  12. Customization of gaming technology and prototyping of rehabilitation applications

    DEFF Research Database (Denmark)

    Herbelin, Bruno; Ciger, Jan; Lewis Brooks, Anthony

    2008-01-01

    The field of rehabilitation has recently seen various experimentations with games using interfaces that require physical activity. In order to establish the basis for developments and experimentations with those interactive systems, we propose a rapid prototyping approach using various commercial...... and to elaborate on the use of such systems. In other words, the availability of a simple prototyping platform with free games and new interfaces already opens the discussion on the design of original rehabilitation applications....... devices and open source software. To demonstrate this idea, we first show how a simple free game can be adapted to specific needs − for training or use by disabled people − by using different sensors and control modes. Similarly, we show that an open on-line virtual world such as Second Life, although...

  13. Solution Prototype

    DEFF Research Database (Denmark)

    Efeoglu, Arkin; Møller, Charles; Serie, Michel

    2013-01-01

    This paper outlines an artifact building and evaluation proposal. Design Science Research (DSR) studies usually consider encapsulated artifact that have relationships with other artifacts. The solution prototype as a composed artifact demands for a more comprehensive consideration in its systematic...... environment. The solution prototype that is composed from blending product and service prototype has particular impacts on the dualism of DSR’s “Build” and “Evaluate”. Since the mix between product and service prototyping can be varied, there is a demand for a more agile and iterative framework. Van de Ven......’s research framework seems to fit this purpose. Van de Ven allows for an iterative research approach to problem solving with flexible starting point. The research activity is the result between the iteration of two dimensions. This framework focuses on the natural evaluation, particularly on ex...

  14. ASSESSMENT OF SURFACE FINISH AND DIMENSIONAL ACCURACY OF TOOLS MANUFACTURED BY METAL CASTING IN RAPID PROTOTYPING SAND MOULDS

    Directory of Open Access Journals (Sweden)

    Nyembwe, K.

    2012-11-01

    Full Text Available In this paper, an initial assessment of the quality parameters of the surface finish and dimensional accuracy of tools made by metal casting in rapid prototyping (RP sand moulds is undertaken. A case study from a local tool room, dealing with the manufacturing of an aluminium die for the lost wax process, is employed. Modern techniques, including surface roughness analysis and three dimensional scanning, are used to determine and understand how each manufacturing step influences the final quality of the cast tool. The best surface finish obtained for the cast die had arithmetic average roughness (Ra and mean average roughness (Rz respectively equal to 3.23m and 11.38m. In terms of dimensional accuracy, 82% of cast-die points coincided with the Computer Aided Design (CAD data, which is within the typical tolerances of sand cast products. The investigation shows that mould coating contributes slightly to the improvement of the cast tool surface finish. The study also found that the additive manufacturing of the sand mould was the chief factor responsible for the loss of dimensional accuracy. These findings indicate that machining will always be required to improve the surface finish and the dimensional accuracy of cast tools in RP sand moulds.

  15. Application of Rapid Prototyping Technique and Intraoperative Navigation System for the Repair and Reconstruction of Orbital Wall Fractures

    Science.gov (United States)

    Cha, Jong Hyun; Lee, Yong Hae; Ruy, Wan Chul; Roe, Young; Moon, Myung Ho

    2016-01-01

    Background Restoring the orbital cavity in large blow out fractures is a challenge for surgeons due to the anatomical complexity. This study evaluated the clinical outcomes and orbital volume after orbital wall fracture repair using a rapid prototyping (RP) technique and intraoperative navigation system. Methods This prospective study was conducted on the medical records and radiology records of 12 patients who had undergone a unilateral blow out fracture reconstruction using a RP technique and an intraoperative navigation system from November 2014 to March 2015. The surgical results were assessed by an ophthalmic examination and a comparison of the preoperative and postoperative orbital volume ratio (OVR) values. Results All patients had a successful treatment outcome without complications. Volumetric analysis revealed a significant decrease in the mean OVR from 1.0952±0.0662 (ranging from 0.9917 to 1.2509) preoperatively to 0.9942±0.0427 (ranging from 0.9394 to 1.0680) postoperatively. Conclusion The application of a RP technique for the repair of orbital wall fractures is a useful tool that may help improve the clinical outcomes by understanding the individual anatomy, determining the operability, and restoring the orbital cavity volume through optimal implant positioning along with an intraoperative navigation system. PMID:28913272

  16. Rapid deployment intrusion detection system

    International Nuclear Information System (INIS)

    Graham, R.H.

    1997-01-01

    A rapidly deployable security system is one that provides intrusion detection, assessment, communications, and annunciation capabilities; is easy to install and configure; can be rapidly deployed, and is reusable. A rapidly deployable intrusion detection system (RADIDS) has many potential applications within the DOE Complex: back-up protection for failed zones in a perimeter intrusion detection and assessment system, intrusion detection and assessment capabilities in temporary locations, protection of assets during Complex reconfiguration, and protection in hazardous locations, protection of assets during Complex reconfiguration, and protection in hazardous locations. Many DOE user-need documents have indicated an interest in a rapidly deployable intrusion detection system. The purpose of the RADIDS project is to design, develop, and implement such a system. 2 figs

  17. Toward Vision Oriented Organization through Foresight Capability Development

    Directory of Open Access Journals (Sweden)

    Gianita BLEOJU

    2014-11-01

    Full Text Available Dealing with complexity is becoming increasingly difficult for organizations, due to limited replicable abilities, once management performance was remunerated by successful decisions on the marketplace. The competitive advantage, based upon current documented organizational management expertise, deployed into patterns of competitive behavior, prove to be unsustainable. Therefore, we assist to a relative emergency of strategic intelligence adjustment framework, to channel the managerial capability mechanisms, from current detective orientation capabilities toward anticipatory ones. Based upon exploitation of an organizational profiling database, we try our contribution to this challenging debate, by formulating recommendations for strategic adjustment and prototype testing of the potential solutions, through a designed transition matrix from market oriented to vision oriented organizations.

  18. Rapid prototyping 3D virtual world interfaces within a virtual factory environment

    Science.gov (United States)

    Kosta, Charles Paul; Krolak, Patrick D.

    1993-01-01

    On-going work into user requirements analysis using CLIPS (NASA/JSC) expert systems as an intelligent event simulator has led to research into three-dimensional (3D) interfaces. Previous work involved CLIPS and two-dimensional (2D) models. Integral to this work was the development of the University of Massachusetts Lowell parallel version of CLIPS, called PCLIPS. This allowed us to create both a Software Bus and a group problem-solving environment for expert systems development. By shifting the PCLIPS paradigm to use the VEOS messaging protocol we have merged VEOS (HlTL/Seattle) and CLIPS into a distributed virtual worlds prototyping environment (VCLIPS). VCLIPS uses the VEOS protocol layer to allow multiple experts to cooperate on a single problem. We have begun to look at the control of a virtual factory. In the virtual factory there are actors and objects as found in our Lincoln Logs Factory of the Future project. In this artificial reality architecture there are three VCLIPS entities in action. One entity is responsible for display and user events in the 3D virtual world. Another is responsible for either simulating the virtual factory or communicating with the real factory. The third is a user interface expert. The interface expert maps user input levels, within the current prototype, to control information for the factory. The interface to the virtual factory is based on a camera paradigm. The graphics subsystem generates camera views of the factory on standard X-Window displays. The camera allows for view control and object control. Control or the factory is accomplished by the user reaching into the camera views to perform object interactions. All communication between the separate CLIPS expert systems is done through VEOS.

  19. Fairchild Stratos Division's Type II prototype lockhopper valve: METC Prototype Test Valve No. F-1 prototype lockhopper valve-testing and development project. Static test report

    Energy Technology Data Exchange (ETDEWEB)

    Goff, D. R.; Cutright, R. L.; Griffith, R. A.; Loomis, R. B.; Maxfield, D. A.; Moritz, R. S.

    1981-10-01

    METC Prototype Test Valve No. F-1 is a hybrid design, based on a segmented ball termed a visor valve, developed and manufactured by Fairchild Stratos Division under contract to the Department of Energy. The valve uses a visor arm that rotates into position and then translates to seal. This valve conditionally completed static testing at METC with clean gas to pressures of 1600 psig and internal valve temperatures to 600/sup 0/F. External leakage was excessive due to leakage through the stuffing box, purge fittings, external bolts, and other assemblies. The stuffing box was repacked several times and redesigned midway through the testing, but external leakage was still excessive. Internal leakage through the seats, except for a few anomalies, was very low throughout the 2409 cycles of testing. As shown by the low internal leakage, the visor valve concept appears to have potential for lock-hopper valve applications. The problems that are present with METC Prototype Test Valve No. F-1 are in the seals, which are equivalent to the shaft and bonnet seals in standard valve designs. The operating conditions at these seals are well within the capabilities of available seal designs and materials. Further engineering and minor modifications should be able to resolve the problems identified during static testing.

  20. An Embedded Systems Laboratory to Support Rapid Prototyping of Robotics and the Internet of Things

    Science.gov (United States)

    Hamblen, J. O.; van Bekkum, G. M. E.

    2013-01-01

    This paper describes a new approach for a course and laboratory designed to allow students to develop low-cost prototypes of robotic and other embedded devices that feature Internet connectivity, I/O, networking, a real-time operating system (RTOS), and object-oriented C/C++. The application programming interface (API) libraries provided permit…

  1. Printing and Prototyping of Tissues and Scaffolds

    Science.gov (United States)

    Derby, Brian

    2012-11-01

    New manufacturing technologies under the banner of rapid prototyping enable the fabrication of structures close in architecture to biological tissue. In their simplest form, these technologies allow the manufacture of scaffolds upon which cells can grow for later implantation into the body. A more exciting prospect is the printing and patterning in three dimensions of all the components that make up a tissue (cells and matrix materials) to generate structures analogous to tissues; this has been termed bioprinting. Such techniques have opened new areas of research in tissue engineering and regenerative medicine.

  2. Knowledge acquisition and rapid protyping of an expert system: Dealing with real world problems

    Science.gov (United States)

    Bailey, Patrick A.; Doehr, Brett B.

    1988-01-01

    The knowledge engineering and rapid prototyping phases of an expert system that does fault handling for a Solid Amine, Water Desorbed CO2 removal assembly for the Environmental Control and Life Support System for space based platforms are addressed. The knowledge acquisition phase for this project was interesting because it could not follow the textbook examples. As a result of this, a variety of methods were used during the knowledge acquisition task. The use of rapid prototyping and the need for a flexible prototype suggested certain types of knowledge representation. By combining various techniques, a representative subset of faults and a method for handling those faults was achieved. The experiences should prove useful for developing future fault handling expert systems under similar constraints.

  3. Logic Foundry: Rapid Prototyping for FPGA-Based DSP Systems

    Directory of Open Access Journals (Sweden)

    Bhattacharyya Shuvra S

    2003-01-01

    Full Text Available We introduce the Logic Foundry, a system for the rapid creation and integration of FPGA-based digital signal processing systems. Recognizing that some of the greatest challenges in creating FPGA-based systems occur in the integration of the various components, we have proposed a system that targets the following four areas of integration: design flow integration, component integration, platform integration, and software integration. Using the Logic Foundry, a system can be easily specified, and then automatically constructed and integrated with system level software.

  4. Cooperative Prototyping Experiments

    DEFF Research Database (Denmark)

    Bødker, Susanne; Grønbæk, Kaj

    1989-01-01

    This paper describes experiments with a design technique that we denote cooperative prototyping. The experiments consider design of a patient case record system for municipal dental clinics in which we used HyperCard, an off the shelf programming environment for the Macintosh. In the ecperiments we...... tried to achieve a fluent work-like evaluation of prototypes where users envisioned future work with a computer tool, at the same time as we made on-line modifications of prototypes in cooperation with the users when breakdown occur in their work-like evaluation. The experiments showed...... that it was possible to make a number of direct manipulation changes of prototypes in cooperation with the users, in interplay with their fluent work-like evaluation of these. However, breakdown occurred in the prototyping process when we reached the limits of the direct manipulation support for modification. From...

  5. A knowledge-based system for prototypical reasoning

    Science.gov (United States)

    Lieto, Antonio; Minieri, Andrea; Piana, Alberto; Radicioni, Daniele P.

    2015-04-01

    In this work we present a knowledge-based system equipped with a hybrid, cognitively inspired architecture for the representation of conceptual information. The proposed system aims at extending the classical representational and reasoning capabilities of the ontology-based frameworks towards the realm of the prototype theory. It is based on a hybrid knowledge base, composed of a classical symbolic component (grounded on a formal ontology) with a typicality based one (grounded on the conceptual spaces framework). The resulting system attempts to reconcile the heterogeneous approach to the concepts in Cognitive Science with the dual process theories of reasoning and rationality. The system has been experimentally assessed in a conceptual categorisation task where common sense linguistic descriptions were given in input, and the corresponding target concepts had to be identified. The results show that the proposed solution substantially extends the representational and reasoning 'conceptual' capabilities of standard ontology-based systems.

  6. Unikabeton Prototype

    DEFF Research Database (Denmark)

    Søndergaard, Asbjørn; Dombernowsky, Per

    2011-01-01

    The Unikabeton prototype structure was developed as the finalization of the cross-disciplinary research project Unikabeton, exploring the architectural potential in linking the computational process of topology optimisation with robot fabrication of concrete casting moulds. The project was elabor......The Unikabeton prototype structure was developed as the finalization of the cross-disciplinary research project Unikabeton, exploring the architectural potential in linking the computational process of topology optimisation with robot fabrication of concrete casting moulds. The project...... of Architecture was to develop a series of optimisation experiments, concluding in the design and optimisation of a full scale prototype concrete structure....

  7. Design for effective development and prototyping of the HL-20

    Science.gov (United States)

    Urie, David M.; Floreck, Paul A.; McMorris, John A.; Elvin, John D.

    1993-10-01

    A feasibility study of the HL-20 personnel launch system (PLS) concept was conducted by a team which focused on creating a PLS design approach and an accelerated development plan consistent with the historical 'Skunk Works' approach to rapid prototyping. Technical design, manufacturing, system testing, and operations and support elements of the predefined baseline concept were evaluated. An initial phase program, featuring a concurrent system test during design and development, leading to the orbital flight of an unmanned HL-20 prototype on a Titan III launch system, was prescribed. A second-phase development and manufacturing plan leading to system operational status was also formulated. Baseline design feature modifications were made when necessary, without compromise to performance, to satisfy the prototype development plan. Technical design details and off-the-shelf hardware candidates were also identified for several subsystems, including the launch-system interface adapter/emergency escape system. The technical feasibility of the system and applicability of the Skunk Works approach to development of the HL-20/PLS were verified.

  8. Operative simulation of anterior clinoidectomy using a rapid prototyping model molded by a three-dimensional printer.

    Science.gov (United States)

    Okonogi, Shinichi; Kondo, Kosuke; Harada, Naoyuki; Masuda, Hiroyuki; Nemoto, Masaaki; Sugo, Nobuo

    2017-09-01

    As the anatomical three-dimensional (3D) positional relationship around the anterior clinoid process (ACP) is complex, experience of many surgeries is necessary to understand anterior clinoidectomy (AC). We prepared a 3D synthetic image from computed tomographic angiography (CTA) and magnetic resonance imaging (MRI) data and a rapid prototyping (RP) model from the imaging data using a 3D printer. The objective of this study was to evaluate anatomical reproduction of the 3D synthetic image and intraosseous region after AC in the RP model. In addition, the usefulness of the RP model for operative simulation was investigated. The subjects were 51 patients who were examined by CTA and MRI before surgery. The size of the ACP, thickness and length of the optic nerve and artery, and intraosseous length after AC were measured in the 3D synthetic image and RP model, and reproducibility in the RP model was evaluated. In addition, 10 neurosurgeons performed AC in the completed RP models to investigate their usefulness for operative simulation. The RP model reproduced the region in the vicinity of the ACP in the 3D synthetic image, including the intraosseous region, at a high accuracy. In addition, drilling of the RP model was a useful operative simulation method of AC. The RP model of the vicinity of ACP, prepared using a 3D printer, showed favorable anatomical reproducibility, including reproduction of the intraosseous region. In addition, it was concluded that this RP model is useful as a surgical education tool for drilling.

  9. Prototype Stilbene Neutron Collar

    Energy Technology Data Exchange (ETDEWEB)

    Prasad, M. K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Shumaker, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Snyderman, N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Verbeke, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wong, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-10-26

    A neutron collar using stilbene organic scintillator cells for fast neutron counting is described for the assay of fresh low enriched uranium (LEU) fuel assemblies. The prototype stilbene collar has a form factor similar to standard He-3 based collars and uses an AmLi interrogation neutron source. This report describes the simulation of list mode neutron correlation data on various fuel assemblies including some with neutron absorbers (burnable Gd poisons). Calibration curves (doubles vs 235U linear mass density) are presented for both thermal and fast (with Cd lining) modes of operation. It is shown that the stilbene collar meets or exceeds the current capabilities of He-3 based neutron collars. A self-consistent assay methodology, uniquely suited to the stilbene collar, using triples is described which complements traditional assay based on doubles calibration curves.

  10. Models and prototypes of biomimetic devices to architectural purposes

    Directory of Open Access Journals (Sweden)

    Silvia Titotto

    2014-12-01

    Full Text Available This paper presents some results of an ongoing interdisciplinary research about models and prototypes of biomimetic devices via installations and the focus of this paper is to outline this research role in architectural purposes as it perpasses the cultural and heritage contexts by being a way of understanding and living in the world as well as taking place in the world as devices or environments that pass on to future generations to use, learn from and be inspired by. Both the theoretical and the experimental work done so far point out that installations built with association of laser cutting and rapid prototyping techniques might be on the best feasible ways for developing and testing new technologies involved in biomimetic devices to architectural purposes that put both tectonics and nature as their central theme. 

  11. Qualitative CFD for Rapid Learning in Industrial and Academic Applications

    Science.gov (United States)

    Variano, Evan

    2010-11-01

    We present a set of tools that allow CFD to be used at an early stage in the design process. Users can rapidly explore the qualitative aspects of fluid flow using real-time simulations that react immediately to design changes. This can guide the design process by fostering an intuitive understanding of fluid dynamics at the prototyping stage. We use an extremely stable Navier-Stokes solver that is available commercially (and free to academic users) plus a custom user interface. The code is designed for the animation and gaming industry, and we exploit the powerful graphical display capabilities to develop a unique human-machine interface. This interface allows the user to efficiently explore the flow in 3D + real time, fostering an intuitive understanding of steady and unsteady flow patterns. There are obvious extensions to use in an academic setting. The trade-offs between accuracy and speed will be discussed in the context of CFD's role in design and education.

  12. The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button.

    Science.gov (United States)

    Swertz, Morris A; Dijkstra, Martijn; Adamusiak, Tomasz; van der Velde, Joeri K; Kanterakis, Alexandros; Roos, Erik T; Lops, Joris; Thorisson, Gudmundur A; Arends, Danny; Byelas, George; Muilu, Juha; Brookes, Anthony J; de Brock, Engbert O; Jansen, Ritsert C; Parkinson, Helen

    2010-12-21

    There is a huge demand on bioinformaticians to provide their biologists with user friendly and scalable software infrastructures to capture, exchange, and exploit the unprecedented amounts of new *omics data. We here present MOLGENIS, a generic, open source, software toolkit to quickly produce the bespoke MOLecular GENetics Information Systems needed. The MOLGENIS toolkit provides bioinformaticians with a simple language to model biological data structures and user interfaces. At the push of a button, MOLGENIS' generator suite automatically translates these models into a feature-rich, ready-to-use web application including database, user interfaces, exchange formats, and scriptable interfaces. Each generator is a template of SQL, JAVA, R, or HTML code that would require much effort to write by hand. This 'model-driven' method ensures reuse of best practices and improves quality because the modeling language and generators are shared between all MOLGENIS applications, so that errors are found quickly and improvements are shared easily by a re-generation. A plug-in mechanism ensures that both the generator suite and generated product can be customized just as much as hand-written software. In recent years we have successfully evaluated the MOLGENIS toolkit for the rapid prototyping of many types of biomedical applications, including next-generation sequencing, GWAS, QTL, proteomics and biobanking. Writing 500 lines of model XML typically replaces 15,000 lines of hand-written programming code, which allows for quick adaptation if the information system is not yet to the biologist's satisfaction. Each application generated with MOLGENIS comes with an optimized database back-end, user interfaces for biologists to manage and exploit their data, programming interfaces for bioinformaticians to script analysis tools in R, Java, SOAP, REST/JSON and RDF, a tab-delimited file format to ease upload and exchange of data, and detailed technical documentation. Existing databases

  13. Human Factors and Technical Considerations for a Computerized Operator Support System Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Ulrich, Thomas Anthony [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lew, Roger Thomas [Idaho National Lab. (INL), Idaho Falls, ID (United States); Medema, Heather Dawne [Idaho National Lab. (INL), Idaho Falls, ID (United States); Boring, Ronald Laurids [Idaho National Lab. (INL), Idaho Falls, ID (United States); Thomas, Kenneth David [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    A prototype computerized operator support system (COSS) has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based on four underlying elements consisting of a digital alarm system, computer-based procedures, PI&D system representations, and a recommender module for mitigation actions. At this point, the prototype simulates an interface to a sensor validation module and a fault diagnosis module. These two modules will be fully integrated in the next version of the prototype. The initial version of the prototype is now operational at the Idaho National Laboratory using the U.S. Department of Energy’s Light Water Reactor Sustainability (LWRS) Human Systems Simulation Laboratory (HSSL). The HSSL is a full-scope, full-scale glass top simulator capable of simulating existing and future nuclear power plant main control rooms. The COSS is interfaced to the Generic Pressurized Water Reactor (gPWR) simulator with industry-typical control board layouts. The glass top panels display realistic images of the control boards that can be operated by touch gestures. A section of the simulated control board was dedicated to the COSS human-system interface (HSI), which resulted in a seamless integration of the COSS into the normal control room environment. A COSS demonstration scenario has been developed for the prototype involving the Chemical & Volume Control System (CVCS) of the PWR simulator. It involves a primary coolant leak outside of containment that would require tripping the reactor if not mitigated in a very short timeframe. The COSS prototype presents a series of operator screens that provide the needed information and soft controls to successfully mitigate the event.

  14. Prototyping real-time systems

    OpenAIRE

    Clynch, Gary

    1994-01-01

    The traditional software development paradigm, the waterfall life cycle model, is defective when used for developing real-time systems. This thesis puts forward an executable prototyping approach for the development of real-time systems. A prototyping system is proposed which uses ESML (Extended Systems Modelling Language) as a prototype specification language. The prototyping system advocates the translation of non-executable ESML specifications into executable LOOPN (Language of Object ...

  15. Clinical decision support for whole genome sequence information leveraging a service-oriented architecture: a prototype.

    Science.gov (United States)

    Welch, Brandon M; Rodriguez-Loya, Salvador; Eilbeck, Karen; Kawamoto, Kensaku

    2014-01-01

    Whole genome sequence (WGS) information could soon be routinely available to clinicians to support the personalized care of their patients. At such time, clinical decision support (CDS) integrated into the clinical workflow will likely be necessary to support genome-guided clinical care. Nevertheless, developing CDS capabilities for WGS information presents many unique challenges that need to be overcome for such approaches to be effective. In this manuscript, we describe the development of a prototype CDS system that is capable of providing genome-guided CDS at the point of care and within the clinical workflow. To demonstrate the functionality of this prototype, we implemented a clinical scenario of a hypothetical patient at high risk for Lynch Syndrome based on his genomic information. We demonstrate that this system can effectively use service-oriented architecture principles and standards-based components to deliver point of care CDS for WGS information in real-time.

  16. Displacement characteristics of a piezoactuator-based prototype microactuator with a hydraulic displacement amplification system

    Energy Technology Data Exchange (ETDEWEB)

    Muralidhara [NMAMIT, Nitte (India); Rao, Rathnamala [NITK, Surathkal (India)

    2015-11-15

    In this study, a new piezoactuator-based prototype microactuator is proposed with a hydraulic displacement amplification system. A piezoactuator is used to deflect a diaphragm which displaces a certain volume of hydraulic fluid into a smaller-diameter piston chamber, thereby amplifying the displacement at the other end of the piston. An electro-mechanical model is implemented to estimate the displacement of a multilayer piezoelectric actuator for the applied input voltage considering the hysteresis behavior. The displacement characteristics of the proposed microactuator are studied for triangular actuation voltage signal. Results of the experiments and simulation of the displacement behavior of the stacked piezoactuator and the amplified displacement of the prototype actuator were compared. Experimental results suggest that the mathematical model developed for the new piezoactuator-based prototype actuator is capable of estimating its displacement behavior accurately, within an error of 1.2%.

  17. Displacement characteristics of a piezoactuator-based prototype microactuator with a hydraulic displacement amplification system

    International Nuclear Information System (INIS)

    Muralidhara; Rao, Rathnamala

    2015-01-01

    In this study, a new piezoactuator-based prototype microactuator is proposed with a hydraulic displacement amplification system. A piezoactuator is used to deflect a diaphragm which displaces a certain volume of hydraulic fluid into a smaller-diameter piston chamber, thereby amplifying the displacement at the other end of the piston. An electro-mechanical model is implemented to estimate the displacement of a multilayer piezoelectric actuator for the applied input voltage considering the hysteresis behavior. The displacement characteristics of the proposed microactuator are studied for triangular actuation voltage signal. Results of the experiments and simulation of the displacement behavior of the stacked piezoactuator and the amplified displacement of the prototype actuator were compared. Experimental results suggest that the mathematical model developed for the new piezoactuator-based prototype actuator is capable of estimating its displacement behavior accurately, within an error of 1.2%.

  18. Design and first plasma measurements of the ITER-ECE prototype radiometer

    Energy Technology Data Exchange (ETDEWEB)

    Austin, M. E.; Brookman, M. W.; Rowan, W. L. [Institute for Fusion Studies, University of Texas at Austin, Austin, Texas 78712 (United States); Danani, S. [ITER-India/Institute for Plasma Research, Bhat, Gandhinagar 382428 (India); Bryerton, E. W.; Dougherty, P. [Virginia Diodes, Inc., Charlottesville, Virginia 22902 (United States)

    2016-11-15

    On ITER, second harmonic optically thick electron cyclotron emission (ECE) in the range of 220-340 GHz will supply the electron temperature (T{sub e}). To investigate the requirements and capabilities prescribed for the ITER system, a prototype radiometer covering this frequency range has been developed by Virginia Diodes, Inc. The first plasma measurements with this instrument have been carried out on the DIII-D tokamak, with lab bench tests and measurements of third through fifth harmonic ECE from high T{sub e} plasmas. At DIII-D the instrument shares the transmission line of the Michelson interferometer and can simultaneously acquire data. Comparison of the ECE radiation temperature from the absolutely calibrated Michelson and the prototype receiver shows that the ITER radiometer provides accurate measurements of the millimeter radiation across the instrument band.

  19. Rapid prototyping of magnetic tunnel junctions with focused ion beam processes

    International Nuclear Information System (INIS)

    Persson, Anders; Thornell, Greger; Nguyen, Hugo

    2010-01-01

    Submicron-sized magnetic tunnel junctions (MTJs) are most often fabricated by time-consuming and expensive e-beam lithography. From a research and development perspective, a short lead time is one of the major concerns. Here, a rapid process scheme for fabrication of micrometre size MTJs with focused ion beam processes is presented. The magnetic properties of the fabricated junctions are investigated in terms of magnetic domain structure, tunnelling magnetoresistance (TMR) and coercivity, with extra attention given to the effect of Ga implantation from the ion beam. In particular, the effect of the implantation on the minimum junction size and the magnetization of the sensing layer are studied. In the latter case, magnetic force microscopy and micromagnetic simulations, with the object-oriented micromagnetic framework (OOMMF), are used to study the magnetization reversal. The fabricated junctions show considerable coercivity both along their hard and easy axes. Interestingly, the sensing layer exhibits two remanent states: one with a single and one with a double domain. The hard axis TMR loop has kinks at about ±20 mT which is attributed to a non-uniform lateral coercivity, where the rim of the junctions, which is subjected to Ga implantation from the flank of the ion beam, is more coercive than the unirradiated centre. The width of the coercive rim is estimated to be 160 nm from the hard axis TMR loop. The easy axis TMR loop shows more coercivity than an unirradiated junction and, this too, is found to stem from the coercive rim, as seen from the simulations. It is concluded that the process scheme has three major advantages. Firstly, it has a high lateral and depth resolution—the depth resolution is enhanced by end point detection—and is capable of making junctions of sizes down towards the limit set by the width of the irradiated rim. Secondly, the most delicate process steps are performed in the unbroken vacuum enabling the use of materials prone to

  20. Convex optimization problem prototyping for image reconstruction in computed tomography with the Chambolle–Pock algorithm

    DEFF Research Database (Denmark)

    Sidky, Emil Y.; Jørgensen, Jakob Heide; Pan, Xiaochuan

    2012-01-01

    The primal–dual optimization algorithm developed in Chambolle and Pock (CP) (2011 J. Math. Imag. Vis. 40 1–26) is applied to various convex optimization problems of interest in computed tomography (CT) image reconstruction. This algorithm allows for rapid prototyping of optimization problems...... for the purpose of designing iterative image reconstruction algorithms for CT. The primal–dual algorithm is briefly summarized in this paper, and its potential for prototyping is demonstrated by explicitly deriving CP algorithm instances for many optimization problems relevant to CT. An example application...

  1. Engineering Prototype for a Compact Medical Dielectric Wall Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Zografos, Anthony; Hening, Andy; Joshkin, Vladimir; Leung, Kevin; Pearson, Dave; Pearce-Percy, Henry; Rougieri, Mario; Parker, Yoko; Weir, John [CPAC, Livermore, CA (United States); Blackfield, Donald; Chen, Yu-Jiuan; Falabella, Steven; Guethlein, Gary; Poole, Brian [Lawrence Livermore National Laboratory, Livermore, CA (United States); Hamm, Robert W. [R and M Technical Enterprises, Pleasanton, CA (United States); Becker, Reinard [Scientific Software Service, Gelnhausen (Germany)

    2011-12-13

    A compact accelerator system architecture based on the dielectric wall accelerator (DWA) for medical proton beam therapy has been developed by the Compact Particle Acceleration Corporation (CPAC). The major subsystems are a Radio Frequency Quadrupole (RFQ) injector linac, a pulsed kicker to select the desired proton bunches, and a DWA linear accelerator incorporating a high gradient insulator (HGI) with stacked Blumleins to produce the required acceleration energy. The Blumleins are switched with solid state laser-driven optical switches integrated into the Blumlein assemblies. Other subsystems include a high power pulsed laser, fiber optic distribution system, electrical charging system, and beam diagnostics. An engineering prototype has been constructed and characterized, and these results will be used within the next three years to develop an extremely compact 150 MeV system capable of modulating energy, beam current, and spot size on a shot-to-shot basis. This paper presents the details the engineering prototype, experimental results, and commercialization plans.

  2. Engineering Prototype for a Compact Medical Dielectric Wall Accelerator

    International Nuclear Information System (INIS)

    Zografos, Anthony; Hening, Andy; Joshkin, Vladimir; Leung, Kevin; Pearson, Dave; Pearce-Percy, Henry; Rougieri, Mario; Parker, Yoko; Weir, John; Blackfield, Donald; Chen, Yu-Jiuan; Falabella, Steven; Guethlein, Gary; Poole, Brian; Hamm, Robert W.; Becker, Reinard

    2011-01-01

    A compact accelerator system architecture based on the dielectric wall accelerator (DWA) for medical proton beam therapy has been developed by the Compact Particle Acceleration Corporation (CPAC). The major subsystems are a Radio Frequency Quadrupole (RFQ) injector linac, a pulsed kicker to select the desired proton bunches, and a DWA linear accelerator incorporating a high gradient insulator (HGI) with stacked Blumleins to produce the required acceleration energy. The Blumleins are switched with solid state laser-driven optical switches integrated into the Blumlein assemblies. Other subsystems include a high power pulsed laser, fiber optic distribution system, electrical charging system, and beam diagnostics. An engineering prototype has been constructed and characterized, and these results will be used within the next three years to develop an extremely compact 150 MeV system capable of modulating energy, beam current, and spot size on a shot-to-shot basis. This paper presents the details the engineering prototype, experimental results, and commercialization plans.

  3. Imagining the prototype

    OpenAIRE

    Brouwer, C. E.; Bhomer, ten, M.; Melkas, H.; Buur, J.

    2013-01-01

    This article reports on the analysis of a design session, employing conversation analysis. In the design session three experts and a designer discuss a prototype of a shirt, which has been developed with the input from these experts. The analysis focuses on the type of involvement of the participants with the prototype and how they explicate the points they make in the discussion with or without making use of the prototype. Three techniques for explicating design issues that exploit the proto...

  4. Dynamic Capabilities and Project Management in Small Software Companies

    DEFF Research Database (Denmark)

    Nørbjerg, Jacob; Nielsen, Peter Axel; Persson, John Stouby

    2017-01-01

    A small software company depends on its capability to adapt to rapid technological and other changes in its environment—its dynamic capabilities. In this paper, we argue that to evolve and maintain its dynamic capabilities a small software company must pay attention to the interaction between...... dynamic capabilities at different levels of the company — particularly between the project management and the company levels. We present a case study of a small software company and show how successful dynamic capabilities at the company level can affect project management in small software companies...

  5. Investigations on Important Properties of the 10 cm x 10 cm GEM Prototype

    CERN Document Server

    Saenboonruang, Kiadtisak; Kulasri, Kittipong; Ritthirong, Anawat

    2015-01-01

    The Gas Electron Multiplier (GEM) detector is one of promising particle and radiation detectors that has been improved greatly from previous gas detectors. The improvement includes better spatial resolutions, higher detection rate capabilities, and flexibilities in designs. In particular, the 10 cm x 10 cm GEM prototype is designed and provided by the Gas Detectors Development group (GDD) at CERN, Switzerland. With its simplicity in operations and designs, while still maintaining high qualities, the GEM prototype is suitable for both start-up and advanced researches. This article aims to report the investigations on some important properties of the 10 cm x 10 cm GEM detector using current measurement and signal counting. Results have shown that gains of the GEM prototype exponentially increase as voltage supplied to the detector increases, while the detector reaches full efficiency (plateau region) when the voltage is greater than 4100 V. In terms of signal sharing between X and Y strips of the readout, X str...

  6. Rapid Prototyping of a Smart Device-based Wireless Reflectance Photoplethysmograph

    Science.gov (United States)

    Ghamari, M.; Aguilar, C.; Soltanpur, C.; Nazeran, H.

    2017-01-01

    This paper presents the design, fabrication, and testing of a wireless heart rate (HR) monitoring device based on photoplethysmography (PPG) and smart devices. PPG sensors use infrared (IR) light to obtain vital information to assess cardiac health and other physiologic conditions. The PPG data that are transferred to a computer undergo further processing to derive the Heart Rate Variability (HRV) signal, which is analyzed to generate quantitative markers of the Autonomic Nervous System (ANS). The HRV signal has numerous monitoring and diagnostic applications. To this end, wireless connectivity plays an important role in such biomedical instruments. The photoplethysmograph consists of an optical sensor to detect the changes in the light intensity reflected from the illuminated tissue, a signal conditioning unit to prepare the reflected light for further signal conditioning through amplification and filtering, a low-power microcontroller to control and digitize the analog PPG signal, and a Bluetooth module to transmit the digital data to a Bluetooth-based smart device such as a tablet. An Android app is then used to enable the smart device to acquire and digitally display the received analog PPG signal in real-time on the smart device. This article is concluded with the prototyping of the wireless PPG followed by the verification procedures of the PPG and HRV signals acquired in a laboratory environment. PMID:28959119

  7. Rapid Prototyping of a Smart Device-based Wireless Reflectance Photoplethysmograph.

    Science.gov (United States)

    Ghamari, M; Aguilar, C; Soltanpur, C; Nazeran, H

    2016-03-01

    This paper presents the design, fabrication, and testing of a wireless heart rate (HR) monitoring device based on photoplethysmography (PPG) and smart devices. PPG sensors use infrared (IR) light to obtain vital information to assess cardiac health and other physiologic conditions. The PPG data that are transferred to a computer undergo further processing to derive the Heart Rate Variability (HRV) signal, which is analyzed to generate quantitative markers of the Autonomic Nervous System (ANS). The HRV signal has numerous monitoring and diagnostic applications. To this end, wireless connectivity plays an important role in such biomedical instruments. The photoplethysmograph consists of an optical sensor to detect the changes in the light intensity reflected from the illuminated tissue, a signal conditioning unit to prepare the reflected light for further signal conditioning through amplification and filtering, a low-power microcontroller to control and digitize the analog PPG signal, and a Bluetooth module to transmit the digital data to a Bluetooth-based smart device such as a tablet. An Android app is then used to enable the smart device to acquire and digitally display the received analog PPG signal in real-time on the smart device. This article is concluded with the prototyping of the wireless PPG followed by the verification procedures of the PPG and HRV signals acquired in a laboratory environment.

  8. Development of an analysis capability for the National Transportation System

    Energy Technology Data Exchange (ETDEWEB)

    Anson, D.; Nelson, R.

    1997-10-24

    The purpose of this report is to examine the Department of Transportation`s (DOT) National Transportation System (NTS) initiative, to document what has been learned, and to outline a National Transportation Network Analysis Capability (NTNAC) based on a ``TRANSIMS-like`` approach. This study was conducted over a two month period at the end of FY1997. The scope of the effort was carefully defined to accommodate the short time horizon and to provide focus to a very large analytical problem. The objectives were to: (1) define the NTS and the NTS problem; (2) identify problem characteristics; (3) describe an analytical solution based on the TRANSIMS approach; (4) identify data requirements and availability; (5) develop criteria for a scenario to be used in a prototype demonstration; and (6) select a scenario for the prototype demonstration.

  9. Rapid response manufacturing (RRM). Final CRADA report

    Energy Technology Data Exchange (ETDEWEB)

    Cain, W.D. [Lockheed Martin Energy Systems, Inc., Oak Ridge, TN (United States); Waddell, W.L. [National Centers for Manufacturing Sciences, Ann Arbor, MI (United States)

    1998-02-10

    US industry is fighting to maintain its competitive edge in the global market place. Markets fluctuate rapidly. Companies have to be able to respond quickly with improved, high quality, cost efficient products. Because companies and their suppliers are geographically distributed, rapid product realization is dependent on the development of a secure integrated concurrent engineering environment operating across multiple business entities. The way products are developed and brought to market can be improved and made more efficient through the proper incorporation of emerging technologies implemented in a secure environment. This documents the work done under this CRADA to develop capabilities, which permit the effective application, incorporation, and use of advanced technologies in a secure environment to facilitate the product realization process. Lockheed Martin Energy Systems (LMES), through a CRADA with the National Center for Manufacturing Sciences (NCMS), worked within a consortium of major industrial firms--Ford, General Motors, Texas Instruments, United Technologies, and Eastman Kodak--and several small suppliers of advanced manufacturing technology--MacNeal-Schwendler Corp., Teknowledge Corp., Cimplex Corp., Concentra, Spatial Technology, and Structural Dynamics Research Corp. (SDRC)--to create infrastructure to support the development and implementation of secure engineering environments for Rapid Response Manufacturing. The major accomplishment achieved under this CRADA was the demonstration of a prototypical implementation of a broad-based generic framework for automating and integrating the design-to-manufacturing activities associated with machined parts in a secure NWC compliant environment. Specifically, methods needed to permit the effective application, incorporation, and use of advanced technologies in a secure environment to facilitate the product realization process were developed and demonstrated. An important aspect of this demonstration was

  10. Prototyping Advanced Control Systems on FPGA

    Directory of Open Access Journals (Sweden)

    Simard Stéphane

    2009-01-01

    Full Text Available In advanced digital control and mechatronics, FPGA-based systems on a chip (SoCs promise to supplant older technologies, such as microcontrollers and DSPs. However, the tackling of FPGA technology by control specialists is complicated by the need for skilled hardware/software partitioning and design in order to match the performance requirements of more and more complex algorithms while minimizing cost. Currently, without adequate software support to provide a straightforward design flow, the amount of time and efforts required is prohibitive. In this paper, we discuss our choice, adaptation, and use of a rapid prototyping platform and design flow suitable for the design of on-chip motion controllers and other SoCs with a need for analog interfacing. The platform consists of a customized FPGA design for the Amirix AP1000 PCI FPGA board coupled with a multichannel analog I/O daughter card. The design flow uses Xilinx System Generator in Matlab/Simulink for system design and test, and Xilinx Platform Studio for SoC integration. This approach has been applied to the analysis, design, and hardware implementation of a vector controller for 3-phase AC induction motors. It also has contributed to the development of CMC's MEMS prototyping platform, now used by several Canadian laboratories.

  11. Supporting Active User Involvment in Prototyping

    DEFF Research Database (Denmark)

    Grønbæk, Kaj

    1990-01-01

    The term prototyping has in recent years become a buzzword in both research and practice of system design due to a number of claimed advantages of prototyping techniques over traditional specification techniques. In particular it is often stated that prototyping facilitates the users' involvement...... in the development process. But prototyping does not automatically imply active user involvement! Thus a cooperative prototyping approach aiming at involving users actively and creatively in system design is proposed in this paper. The key point of the approach is to involve users in activities that closely couple...... development of prototypes to early evaluation of prototypes in envisioned use situations. Having users involved in such activities creates new requirements for tool support. Tools that support direct manipulation of prototypes and simulation of behaviour have shown promise for cooperative prototyping...

  12. Engineering prototypes for theta-pinch devices

    International Nuclear Information System (INIS)

    Hansborough, L.D.; Hammer, C.F.; Hanks, K.W.; McDonald, T.E.; Nunnally, W.C.

    1975-01-01

    Past, present, and future engineering prototypes for theta-pinch plasma-physics devices at Los Alamos Scientific Laboratory are discussed. Engineering prototypes are designed to test and evaluate all components under system conditions expected on actual plasma-physics experimental devices. The importance of engineering prototype development increases as the size and complexity of the plasma-physics device increases. Past experiences with the Scyllac prototype and the Staged Theta-Pinch prototype are discussed and evaluated. The design of the proposed Staged Scyllac prototype and the Large Staged Scyllac implosion prototype assembly are discussed

  13. The Orphee reactor current status and proposed enhancement of experimental capabilities

    International Nuclear Information System (INIS)

    Breant, P.

    1990-01-01

    This report provides a description of the Orphee reactor, together with a rapid assessment of its experimental and research capabilities. The plans for enhancing the reactor's experimental capabilities are also presented. (author)

  14. Prototype Performance of Novel Muon Telescope Detector at STAR

    International Nuclear Information System (INIS)

    Ruan, L.

    2008-01-01

    Research on a large-area, cost-effective Muon Telescope Detector (MTD) has been carried out for RHIC and for next generation detectors at future QCD Lab. We utilize state-of-the-art multi-gap resistive plate chambers with large modules and long readout strips in detector design. The results from cosmic ray and beam test will be presented to address intrinsic timing and spatial resolution for a Long-MRPC. The prototype performance of a novel muon telescope detector at STAR will be reported, including muon identification capability, timing and spatial resolution

  15. Prototype performance of novel muon telescope detector at STAR

    International Nuclear Information System (INIS)

    Ruan, L.; Ames, V.

    2011-01-01

    Research on a large-area, cost-effective Muon Telescope Detector has been carried out for RHIC and for next generation detectors at future QCD Lab. We utilize state-of-the-art multi-gap resistive plate chambers with large modules and long readout strips in detector design. The results from cosmic ray and beam test will be presented to address intrinsic timing and spatial resolution for a Long-MRPC. The prototype performance of a novel muon telescope detector at STAR will be reported, including muon identification capability, timing and spatial resolution. (author)

  16. Prototipaje rápido de estructuras craneofaciales Rapid prototyping of craniofacial structures

    Directory of Open Access Journals (Sweden)

    Juan Felipe Isaza

    2008-12-01

    Full Text Available Este artículo presenta una descripción de la tecnología de Prototipaje Rápido o Rapid Prototyping (RP aplicada a la medicina, específicamente a problemas craneofaciales, con la cual se pueden fabricar modelos sólidos 3D por adición de material. A su vez se describe una aplicación a partir de la simulación de una cirugía para insertar cuatro implantes mandibulares, los cuales constituyen la base de una prótesis fija soportada por implantes. La simulación del procedimiento quirúrgico comenzó con la obtención de la geometría mandibular a partir del procesamiento de imágenes biomédicas, provenientes de una Tomografia Axial Computarizada (TAC de una mujer adulta, totalmente edéntula. Dicho proceso se realizó utilizando el software GIB Points 3D, desarrollado dentro del presente trabajo. Con el software se obtuvo un archivo de texto con la nube de puntos 3D de la mandíbula que posteriormente fue exportado a ProEngineer Wildfire 3.0, desde el cual se generó un archivo en formato estándar STL, compatible con la mayoría de máquinas RP. La tecnología usada para la impresión 3D, fue la de “deposición de hilo fundido” o Fused Deposition Modeling (FDM. Se logró obtener un modelo plástico de una mandíbula, de gran calidad anatómica y dimensional, utilizando tecnología disponible enColombia. Además, se simuló con éxito el procedimiento quirúrgico para lainstalación de cuatro implantes utilizando las herramientas que se usarían enla cirugía real. En general, la metodología implementada puede ser utilizadapara la planificación quirúrgica y así evitar procedimientos de ensayo y errorque puedan poner en riesgo la salud del paciente. También como herramientade comunicación para explicarle al paciente los procedimientos quirúrgicos aque será sometido. Además, puede ser usado con fines docentes para el entrenamientode estudiantes, haciendo más efectivos los procesos de aprendizajeen el ámbito clínico que a su

  17. Fabrication of channeled scaffolds with ordered array of micro-pores through microsphere leaching and indirect Rapid Prototyping technique.

    Science.gov (United States)

    Tan, J Y; Chua, C K; Leong, K F

    2013-02-01

    Advanced scaffold fabrication techniques such as Rapid Prototyping (RP) are generally recognized to be advantageous over conventional fabrication methods in terms architectural control and reproducibility. Yet, most RP techniques tend to suffer from resolution limitations which result in scaffolds with uncontrollable, random-size pores and low porosity, albeit having interconnected channels which is characteristically present in most RP scaffolds. With the increasing number of studies demonstrating the profound influences of scaffold pore architecture on cell behavior and overall tissue growth, a scaffold fabrication method with sufficient architectural control becomes imperative. The present study demonstrates the use of RP fabrication techniques to create scaffolds having interconnected channels as well as controllable micro-size pores. Adopted from the concepts of porogen leaching and indirect RP techniques, the proposed fabrication method uses monodisperse microspheres to create an ordered, hexagonal closed packed (HCP) array of micro-pores that surrounds the existing channels of the RP scaffold. The pore structure of the scaffold is shaped using a single sacrificial construct which comprises the microspheres and a dissolvable RP mold that were sintered together. As such, the size of pores as well as the channel configuration of the scaffold can be tailored based on the design of the RP mold and the size of microspheres used. The fabrication method developed in this work can be a promising alternative way of preparing scaffolds with customized pore structures that may be required for specific studies concerning cell-scaffold interactions.

  18. Fabrication and characterization of a rapid prototyped tissue engineering scaffold with embedded multicomponent matrix for controlled drug release

    Science.gov (United States)

    Chen, Muwan; Le, Dang QS; Hein, San; Li, Pengcheng; Nygaard, Jens V; Kassem, Moustapha; Kjems, Jørgen; Besenbacher, Flemming; Bünger, Cody

    2012-01-01

    Bone tissue engineering implants with sustained local drug delivery provide an opportunity for better postoperative care for bone tumor patients because these implants offer sustained drug release at the tumor site and reduce systemic side effects. A rapid prototyped macroporous polycaprolactone scaffold was embedded with a porous matrix composed of chitosan, nanoclay, and β-tricalcium phosphate by freeze-drying. This composite scaffold was evaluated on its ability to deliver an anthracycline antibiotic and to promote formation of mineralized matrix in vitro. Scanning electronic microscopy, confocal imaging, and DNA quantification confirmed that immortalized human bone marrow-derived mesenchymal stem cells (hMSC-TERT) cultured in the scaffold showed high cell viability and growth, and good cell infiltration to the pores of the scaffold. Alkaline phosphatase activity and osteocalcin staining showed that the scaffold was osteoinductive. The drug-release kinetics was investigated by loading doxorubicin into the scaffold. The scaffolds comprising nanoclay released up to 45% of the drug for up to 2 months, while the scaffold without nanoclay released 95% of the drug within 4 days. Therefore, this scaffold can fulfill the requirements for both bone tissue engineering and local sustained release of an anticancer drug in vitro. These results suggest that the scaffold can be used clinically in reconstructive surgery after bone tumor resection. Moreover, by changing the composition and amount of individual components, the scaffold can find application in other tissue engineering areas that need local sustained release of drug. PMID:22904634

  19. Autobalancing and FDIR for a space-based centrifuge prototype

    Science.gov (United States)

    Wilson, Edward; Mah, Robert W.

    2005-01-01

    This report summarizes centrifuge-related work performed at the Smart Systems Research Laboratory at NASA Ames Research Center's Computational Sciences Division from 1995 through 2003. The goal is to develop an automated system that will sense an imbalance (both static and dynamic3) in a centrifuge and issue control commands to drive counterweights to eliminate the effects of the imbalance. This autobalancing development began when the ISS centrifuge design was not yet finalized, and was designed to work with the SSRL Centrifuge laboratory prototype, constructed in 1993-1995. Significant differences between that prototype and the current International Space Station (ISS) Centrifuge design are that: the spin axis for the SSRL Centrifuge prototype can translate freely in x and y, but not wobble, whereas the ISS centrifuge spin axis has 3 translational and two rotational degrees of freedom, supported by a vibration 34. The imbalance sensors are strained gauges both in the rotor and the stator, measuring the imbalance forces, whereas the ISS centrifuge uses eddy current displacement sensors to measure the displacements resulting from imbalance. High fidelity autobalancing and FDIR systems (for both counterweights and strain gauges) are developed and tested in MATLAB simulation, for the SSRL Centrifuge configuration. Hardware implementation of the autobalancing technology was begun in 1996, but was terminated due to lack of funding. The project lay dormant until 2001-2002 when the FDIR capability was added.

  20. A prototype for the PASS Permanent All Sky Survey

    Science.gov (United States)

    Deeg, H. J.; Alonso, R.; Belmonte, J. A.; Horne, K.; Alsubai, K.; Collier Cameron, A.; Doyle, L. R.

    2004-10-01

    A prototype system for the Permanent All Sky Survey (PASS) project is presented. PASS is a continuous photometric survey of the entire celestial sphere with a high temporal resolution. Its major objectives are the detection of all giant-planet transits (with periods up to some weeks) across stars up to mag 10.5, and to deliver continuously photometry that is useful for the study of any variable stars. The prototype is based on CCD cameras with short focal length optics on a fixed mount. A small dome to house it at Teide Observatory, Tenerife, is currently being constructed. A placement at the antarctic Dome C is also being considered. The prototype will be used for a feasibility study of PASS, to define the best observing strategies, and to perform a detailed characterization of the capabilities and scope of the survey. Afterwards, a first partial sky surveying will be started with it. That first survey may be able to detect transiting planets during its first few hundred hours of operation. It will also deliver a data set around which software modules dealing with the various scientific objectives of PASS will be developed. The PASS project is still in its early phase and teams interested in specific scientific objectives, in providing technical expertise, or in participating with own observations are invited to collaborate.

  1. EPCiR prototype

    DEFF Research Database (Denmark)

    2003-01-01

    A prototype of a residential pervasive computing platform based on OSGi involving among other a mock-up of an health care bandage.......A prototype of a residential pervasive computing platform based on OSGi involving among other a mock-up of an health care bandage....

  2. ITER ECRH upper launcher torus diamond window – Prototyping, testing and qualification

    Energy Technology Data Exchange (ETDEWEB)

    Schreck, Sabine, E-mail: sabine.schreck@kit.edu [Karlsruhe Institute of Technology, Institute for Applied Materials, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany); Aiello, Gaetano; Meier, Andreas; Strauss, Dirk [Karlsruhe Institute of Technology, Institute for Applied Materials, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany); Ikeda, Ryosuke; Oda, Yasuhisa; Sakamoto, Keishi; Takahashi, Koji [Japan Atomic Energy Agency (JAEA), Plasma Heating Technology Group, 801-1 Mukoyama, Naka, Ibaraki 311-0193 (Japan); Scherer, Theo [Karlsruhe Institute of Technology, Institute for Applied Materials, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany)

    2015-10-15

    Highlights: • The diamond window prototype shows a very good transmission capability during high power RF experiments. • An ad-hoc qualification programme for the diamond torus window is being developed (contract between KIT and F4E). • The window design has been updated focused on its mechanical integrity and manufacturing aspects. - Abstract: The diamond window assembly is part of the ITER primary vacuum boundary and acts as the first tritium barrier and therefore it is classified as Safety/Protection Important Component (SIC/PIC). It consists of an ultra-low loss CVD diamond disk mounted in a system of metallic parts (copper/steel) and has to fulfil adequate transmission capability for high power mm-waves. High power RF experiments with a 1st window prototype had shown parasitic heating due to small gaps in the housing. After a design optimization directed to the mm-wave properties, the parasitic excitations of oscillations have been avoided in a 2nd prototype. This one is equipped with inserted waveguide structures, which cover gaps in the metallic structure of the window housing. From high power RF-measurements with a 0.86 MW/100 s pulse a loss tangent of 7.1 × 10{sup −6} could be estimated, corresponding to an increase of temperature of only 120 mK between inlet and outlet of the cooling system. The diamond window assemblies cannot be entirely covered by codes and standards. To comply with the French safety regulations, instead an ad-hoc qualification programme is required, being developed in the framework of a contract between KIT and F4E. A new prototype (3rd) will be built, which is designed to fit to the single HELICOFLEX sealed waveguide structures of the ex-vessel mm-system of the EC upper launcher (UL). The testing programme ranges from mechanical to vacuum tests up to dielectric loss measurements at low and high power. A clear definition of the testing requirements and of the acceptance criteria is necessary as well as a complete

  3. Novel method of fabricating individual trays for maxillectomy patients by computer-aided design and rapid prototyping.

    Science.gov (United States)

    Huang, Zhi; Wang, Xin-zhi; Hou, Yue-Zhong

    2015-02-01

    Making impressions for maxillectomy patients is an essential but difficult task. This study developed a novel method to fabricate individual trays by computer-aided design (CAD) and rapid prototyping (RP) to simplify the process and enhance patient safety. Five unilateral maxillectomy patients were recruited for this study. For each patient, a computed tomography (CT) scan was taken. Based on the 3D surface reconstruction of the target area, an individual tray was manufactured by CAD/RP. With a conventional custom tray as control, two final impressions were made using the different types of tray for each patient. The trays were sectioned, and in each section the thickness of the material was measured at six evenly distributed points. Descriptive statistics and paired t-test were used to examine the difference of the impression thickness. SAS 9.3 was applied in the statistical analysis. Afterwards, all casts were then optically 3D scanned and compared digitally to evaluate the feasibility of this method. Impressions of all five maxillectomy patients were successfully made with individual trays fabricated by CAD/RP and traditional trays. The descriptive statistics of impression thickness measurement showed slightly more uneven results in the traditional trays, but no statistical significance was shown. A 3D digital comparison showed acceptable discrepancies within 1 mm in the majority of cast areas. The largest difference of 3 mm was observed in the buccal wall of the defective areas. Moderate deviations of 1 to 2 mm were detected in the buccal and labial vestibular groove areas. This study confirmed the feasibility of a novel method of fabricating individual trays by CAD/RP. Impressions made by individual trays manufactured using CAD/RP had a uniform thickness, with an acceptable level of accuracy compared to those made through conventional processes. © 2014 by the American College of Prosthodontists.

  4. Fast-prototyping of VLSI

    International Nuclear Information System (INIS)

    Saucier, G.; Read, E.

    1987-01-01

    Fast-prototyping will be a reality in the very near future if both straightforward design methods and fast manufacturing facilities are available. This book focuses, first, on the motivation for fast-prototyping. Economic aspects and market considerations are analysed by European and Japanese companies. In the second chapter, new design methods are identified, mainly for full custom circuits. Of course, silicon compilers play a key role and the introduction of artificial intelligence techniques sheds a new light on the subject. At present, fast-prototyping on gate arrays or on standard cells is the most conventional technique and the third chapter updates the state-of-the art in this area. The fourth chapter concentrates specifically on the e-beam direct-writing for submicron IC technologies. In the fifth chapter, a strategic point in fast-prototyping, namely the test problem is addressed. The design for testability and the interface to the test equipment are mandatory to fulfill the test requirement for fast-prototyping. Finally, the last chapter deals with the subject of education when many people complain about the lack of use of fast-prototyping in higher education for VLSI

  5. Utility of Big Area Additive Manufacturing (BAAM) For The Rapid Manufacture of Customized Electric Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Love, Lonnie J [ORNL

    2015-08-01

    This Oak Ridge National Laboratory (ORNL) Manufacturing Development Facility (MDF) technical collaboration project was conducted in two phases as a CRADA with Local Motors Inc. Phase 1 was previously reported as Advanced Manufacturing of Complex Cyber Mechanical Devices through Community Engagement and Micro-manufacturing and demonstrated the integration of components onto a prototype body part for a vehicle. Phase 2 was reported as Utility of Big Area Additive Manufacturing (BAAM) for the Rapid Manufacture of Customized Electric Vehicles and demonstrated the high profile live printing of an all-electric vehicle using ONRL s Big Area Additive Manufacturing (BAAM) technology. This demonstration generated considerable national attention and successfully demonstrated the capabilities of the BAAM system as developed by ORNL and Cincinnati, Inc. and the feasibility of additive manufacturing of a full scale electric vehicle as envisioned by the CRADA partner Local Motors, Inc.

  6. PhoneSat: Ground Testing of a Phone-Based Prototype Bus

    Science.gov (United States)

    Felix, Carmen; Howard, Benjamin; Reyes, Matthew; Snarskiy, Fedor; Hickman, Ryan; Boshuizen, Christopher; Marshall, William

    2010-01-01

    Most of the key capabilities that are requisite of a satellite bus are housed in today's smart phones. PhoneSat refers to an initiative to build a ground-based prototype vehicle that could all the basic functionality of a satellite, including attitude control, using a smart Phone as its central hardware. All components used were also low cost Commercial off the Shelf (COTS). In summer 2009, an initial prototype was created using the LEGO Mindstorm toolkit demonstrating simple attitude control. Here we report on a follow up initiative to design, build and test a vehicle based on the Google s smart phone Nexus One. The report includes results from initial thermal-vacuum chamber tests and low altitude sub-orbital rocket flights which show that, at least for short durations, the Nexus One phone is able to withstand key aspects of the space environment without failure. We compare the sensor data from the Phone's accelerometers and magnetometers with that of an external microelectronic inertial measurement unit.

  7. Trade-off study on the power capacity of a prototype SFR in Korea

    International Nuclear Information System (INIS)

    Baek, M. H.; Kim, S. J.; Yoo, J.; Bae, I. H.

    2012-01-01

    The major roles of a prototype SFR are to provide irradiation test capability for the fuel and structure materials, and to obtain operational experiences of systems. Due to a compromise between the irradiation capability and construction costs, the power level should be properly determined. In this paper, a trade-off study on the power level of the prototype SFR was performed from a neutronics viewpoint. To select candidate cores, the parametric study of pin diameters was estimated using 20 wt.% uranium fuel. The candidate cores of different power levels, 125 MWt, 250 MWt, 400 MWt, and 500 MWt, were compared with the 1500 MWt reference core. The resulting core performance and economic efficiency indices became insensitive to the power at about 400-500 MWt and sharply deteriorated at about 125-250 MWt with decreasing core sizes. Fuel management scheme, TRU core performance comparing with uranium core, and sodium void reactivity were also evaluated with increasing power levels. It is found that increasing the number of batches showed higher burnup performance and economic efficiency. However, increasing the cycle length showed the trends in lower economic efficiency. Irradiation performance of TRU and enriched TRU cores was improved about 20 % and 50 %, respectively. The maximum sodium void reactivity of 5.2$ was confirmed less than the design limit of 7.5$. As a result, the power capacity of the prototype SFR should not be less than 250 MWt and would be appropriate at ∼ 500 MWt considering the performance and economic efficiency. (authors)

  8. Prototypes as Platforms for Participation

    DEFF Research Database (Denmark)

    Horst, Willem

    developers, and design it accordingly. Designing a flexible prototype in combination with supportive tools to be used by both interaction designers and non-designers during development is introduced as a way to open up the prototyping process to these users. Furthermore I demonstrate how such a flexible...... on prototyping, by bringing to attention that the prototype itself is an object of design, with its users and use context, which deserves further attention. Moreover, in this work I present concrete tools and methods that can be used by interaction designers in practice. As such this work addresses both......The development of interactive products in industry is an activity involving different disciplines – such as different kinds of designers, engineers, marketers and managers – in which prototypes play an important role. On the one hand, prototypes can be powerful boundary objects and an effective...

  9. Laparoscopic prototype for optical sealing of renal blood vessels

    Science.gov (United States)

    Hardy, Luke A.; Hutchens, Thomas C.; Larson, Eric R.; Gonzalez, David A.; Chang, Chun-Hung; Nau, William H.; Fried, Nathaniel M.

    2017-02-01

    Energy-based, radiofrequency and ultrasonic devices provide rapid sealing of blood vessels during laparoscopic procedures. We are exploring infrared lasers as an alternative for vessel sealing with less collateral thermal damage. Previous studies demonstrated vessel sealing in an in vivo porcine model using a 1470-nm laser. However, the initial prototype was designed for open surgery and featured tissue clasping and light delivery mechanisms incompatible with laparoscopic surgery. In this study, a laparoscopic prototype similar to devices in surgical use was developed, and tests were conducted on porcine renal blood vessels. The 5-mm-OD prototype featured a traditional Maryland jaw configuration. Laser energy was delivered through a 550-μm-core fiber and side-delivery from the lower jaw, with beam dimensions of 18-mm-length x 1.2-mm-width. The 1470-nm diode laser delivered 68 W with 3 s activation time. A total of 69 porcine renal vessels with mean diameter of 3.3 +/- 1.7 mm were tested, ex vivo. Vessels smaller than 5 mm were consistently sealed (48/51) with burst pressures greater than malignant hypertension blood pressure (180 mmHg), averaging 1038 +/- 474 mmHg. Vessels larger than 5 mm were not consistently sealed (6/18), yielding burst pressures of only 174 +/- 221 mmHg. Seal width, thermal damage zone, and thermal spread averaged 1.7 +/- 0.8, 3.4 +/- 0.7, and 1.0 +/- 0.4 mm. A novel optical laparoscopic prototype with 5-mm- OD shaft integrated within a standard Maryland jaw design consistently sealed vessels less than 5 mm with minimal thermal spread. Further in vivo studies are planned to test performance across a variety of vessels and tissues.

  10. Effect of annealing procedure on the bonding of ceramic to cobalt-chromium alloys fabricated by rapid prototyping.

    Science.gov (United States)

    Tulga, Ayca

    2018-04-01

    An annealing procedure is a heat treatment process to improve the mechanical properties of cobalt-chromium (Co-Cr) alloys. However, information is lacking about the effect of the annealing process on the bonding ability of ceramic to Co-Cr alloys fabricated by rapid prototyping. The purpose of this in vitro study was to evaluate the effects of the fabrication techniques and the annealing procedure on the shear bond strength of ceramic to Co-Cr alloys fabricated by different techniques. Ninety-six cylindrical specimens (10-mm diameter, 10-mm height) made of Co-Cr alloy were prepared by casting (C), milling (M), direct process powder-bed (LaserCUSING) with and without annealing (CL+, CL), and direct metal laser sintering (DMLS) with annealing (EL+) and without annealing (EL). After the application of ceramic to the metal specimens, the metal-ceramic bond strength was assessed using a shear force test at a crosshead speed of 0.5 mm/min. Shear bond strength values were statistically analyzed by 1-way ANOVA and Tukey multiple comparison tests (α=.05). Although statistically significant differences were found among the 3 groups (M, 29.87 ±2.06; EL, 38.92 ±2.04; and CL+, 40.93 ±2.21; P=.002), no significant differences were found among the others (P>.05). The debonding surfaces of all specimens exhibited mixed failure mode. These results showed that the direct process powder-bed method is promising in terms of metal-ceramic bonding ability. The manufacturing technique of Co-Cr alloys and the annealing process influence metal-ceramic bonding. Copyright © 2017 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  11. A prototype analysis of vengeance

    NARCIS (Netherlands)

    Elshout, Maartje; Nelissen, Rob; van Beest, Ilja

    2015-01-01

    The authors examined the concept of vengeance from a prototype perspective. In 6 studies, the prototype structure of vengeance was mapped. Sixty-nine features of vengeance were identified (Study 1), and rated on centrality (Study 2). Further studies confirmed the prototype structure. Compared to

  12. Rapid Stencil Mask Fabrication Enabled One-Step Polymer-Free Graphene Patterning and Direct Transfer for Flexible Graphene Devices.

    Science.gov (United States)

    Yong, Keong; Ashraf, Ali; Kang, Pilgyu; Nam, SungWoo

    2016-04-27

    We report a one-step polymer-free approach to patterning graphene using a stencil mask and oxygen plasma reactive-ion etching, with a subsequent polymer-free direct transfer for flexible graphene devices. Our stencil mask is fabricated via a subtractive, laser cutting manufacturing technique, followed by lamination of stencil mask onto graphene grown on Cu foil for patterning. Subsequently, micro-sized graphene features of various shapes are patterned via reactive-ion etching. The integrity of our graphene after patterning is confirmed by Raman spectroscopy. We further demonstrate the rapid prototyping capability of a stretchable, crumpled graphene strain sensor and patterned graphene condensation channels for potential applications in sensing and heat transfer, respectively. We further demonstrate that the polymer-free approach for both patterning and transfer to flexible substrates allows the realization of cleaner graphene features as confirmed by water contact angle measurements. We believe that our new method promotes rapid, facile fabrication of cleaner graphene devices, and can be extended to other two dimensional materials in the future.

  13. NASA Stennis Space Center Integrated System Health Management Test Bed and Development Capabilities

    Science.gov (United States)

    Figueroa, Fernando; Holland, Randy; Coote, David

    2006-01-01

    Integrated System Health Management (ISHM) is a capability that focuses on determining the condition (health) of every element in a complex System (detect anomalies, diagnose causes, prognosis of future anomalies), and provide data, information, and knowledge (DIaK)-not just data-to control systems for safe and effective operation. This capability is currently done by large teams of people, primarily from ground, but needs to be embedded on-board systems to a higher degree to enable NASA's new Exploration Mission (long term travel and stay in space), while increasing safety and decreasing life cycle costs of spacecraft (vehicles; platforms; bases or outposts; and ground test, launch, and processing operations). The topics related to this capability include: 1) ISHM Related News Articles; 2) ISHM Vision For Exploration; 3) Layers Representing How ISHM is Currently Performed; 4) ISHM Testbeds & Prototypes at NASA SSC; 5) ISHM Functional Capability Level (FCL); 6) ISHM Functional Capability Level (FCL) and Technology Readiness Level (TRL); 7) Core Elements: Capabilities Needed; 8) Core Elements; 9) Open Systems Architecture for Condition-Based Maintenance (OSA-CBM); 10) Core Elements: Architecture, taxonomy, and ontology (ATO) for DIaK management; 11) Core Elements: ATO for DIaK Management; 12) ISHM Architecture Physical Implementation; 13) Core Elements: Standards; 14) Systematic Implementation; 15) Sketch of Work Phasing; 16) Interrelationship Between Traditional Avionics Systems, Time Critical ISHM and Advanced ISHM; 17) Testbeds and On-Board ISHM; 18) Testbed Requirements: RETS AND ISS; 19) Sustainable Development and Validation Process; 20) Development of on-board ISHM; 21) Taxonomy/Ontology of Object Oriented Implementation; 22) ISHM Capability on the E1 Test Stand Hydraulic System; 23) Define Relationships to Embed Intelligence; 24) Intelligent Elements Physical and Virtual; 25) ISHM Testbeds and Prototypes at SSC Current Implementations; 26) Trailer

  14. Resource Prospector (RP) - Early Prototyping and Development

    Science.gov (United States)

    Andrews, D.; Colaprete, A.; Quinn, J.; Bluethmann, B.; Trimble, J.

    2015-01-01

    The Resource Prospector (RP) is an In-Situ Resource Utilization (ISRU) technology demonstration mission under study by the NASA Human Exploration and Operations Mission Directorate's (HEOMD) Advanced Exploration Systems (AES) Division. The mission, currently planned to launch in 2020, will demonstrate extraction of oxygen from lunar regolith to validate ISRU capability. The mission will address key Strategic Knowledge Gaps (SKGs) for robotic and human exploration to the Moon, Near Earth Asteroids (NEAs), and ultimately Mars, as well as meet the strategic goals of the Global Exploration Roadmap (GER), offered by the International Space Exploration Coordination Group (ISECG). In this roadmap, the use of local resources is specifically addressed relating to human exploration. RP will provide knowledge to inform the selection of future mission destinations, support the development of exploration systems, and reduce the risk associated with human exploration. Expanding human presence beyond low-Earth orbit to asteroids and Mars will require the maximum possible use of local materials, so-called in-situ resources. The moon presents a unique destination to conduct robotic investigations that advance ISRU capabilities, as well as providing significant exploration and science value. Lunar regolith contains useful resources such as oxygen, water, silicon, and light metals, like aluminum and titanium. Oxygen can be separated from the regolith for life support (breathable air), or used to create rocket propellant (oxidizer). Regolith can be used to protect against radiation exposure, be processed into solar cells, or used to manufacture construction materials such as bricks and glass. RP will characterize the constituents and distribution of water and other volatiles at the poles of the Moon, enabling innovative uses of local resources, in addition to validating ISRU capabilities. This capability, as well as a deeper understanding of regolith, will be valuable in the

  15. Indirect rapid prototyping of sol-gel hybrid glass scaffolds for bone regeneration - Effects of organic crosslinker valence, content and molecular weight on mechanical properties.

    Science.gov (United States)

    Hendrikx, Stephan; Kascholke, Christian; Flath, Tobias; Schumann, Dirk; Gressenbuch, Mathias; Schulze, F Peter; Hacker, Michael C; Schulz-Siegmund, Michaela

    2016-04-15

    We present a series of organic/inorganic hybrid sol-gel derived glasses, made from a tetraethoxysilane-derived silica sol (100% SiO2) and oligovalent organic crosslinkers functionalized with 3-isocyanatopropyltriethoxysilane. The material was susceptible to heat sterilization. The hybrids were processed into pore-interconnected scaffolds by an indirect rapid prototyping method, described here for the first time for sol-gel glass materials. A large panel of polyethylene oxide-derived 2- to 4-armed crosslinkers of molecular weights ranging between 170 and 8000Da were incorporated and their effect on scaffold mechanical properties was investigated. By multiple linear regression, 'organic content' and the 'content of ethylene oxide units in the hybrid' were identified as the main factors that determined compressive strength and modulus, respectively. In general, 3- and 4-armed crosslinkers performed better than linear molecules. Compression tests and cell culture experiments with osteoblast-like SaOS-2 cells showed that macroporous scaffolds can be produced with compressive strengths of up to 33±2MPa and with a pore structure that allows cells to grow deep into the scaffolds and form mineral deposits. Compressive moduli between 27±7MPa and 568±98MPa were obtained depending on the hybrid composition and problems associated with the inherent brittleness of sol-gel glass materials could be overcome. SaOS-2 cells showed cytocompatibility on hybrid glass scaffolds and mineral accumulation started as early as day 7. On day 14, we also found mineral accumulation on control hybrid glass scaffolds without cells, indicating a positive effect of the hybrid glass on mineral accumulation. We produced a hybrid sol-gel glass material with significantly improved mechanical properties towards an application in bone regeneration and processed the material into macroporous scaffolds of controlled architecture by indirect rapid prototyping. We were able to produce macroporous materials

  16. RAPID AUTOMATED RADIOCHEMICAL ANALYZER FOR DETERMINATION OF TARGETED RADIONUCLIDES IN NUCLEAR PROCESS STREAMS

    International Nuclear Information System (INIS)

    O'Hara, Matthew J.; Durst, Philip C.; Grate, Jay W.; Egorov, Oleg; Devol, Timothy A.

    2008-01-01

    Some industrial process-scale plants require the monitoring of specific radionuclides as an indication of the composition of their feed streams or as indicators of plant performance. In this process environment, radiochemical measurements must be fast, accurate, and reliable. Manual sampling, sample preparation, and analysis of process fluids are highly precise and accurate, but tend to be expensive and slow. Scientists at Pacific Northwest National Laboratory (PNNL) have assembled and characterized a fully automated prototype Process Monitor instrument which was originally designed to rapidly measure Tc-99 in the effluent streams of the Waste Treatment Plant at Hanford, WA. The system is capable of a variety of tasks: extraction of a precise volume of sample, sample digestion/analyte redox adjustment, column-based chemical separations, flow-through radiochemical detection and data analysis/reporting. The system is compact, its components are fluidically inter-linked, and analytical results can be immediately calculated and electronically reported. It is capable of performing a complete analytical cycle in less than 15 minutes. The system is highly modular and can be adapted to a variety of sample types and analytical requirements. It exemplifies how automation could be integrated into reprocessing facilities to support international nuclear safeguards needs

  17. Evaluation of 3D printed optofluidic smart glass prototypes.

    Science.gov (United States)

    Wolfe, Daniel; Goossen, K W

    2018-01-22

    Smart glass or smart windows are an innovative technology used for thermal management, energy efficiency, and privacy applications. Notable commercially available smart glass relies on an electric stimuli to modulate the glass from a transparent to a translucent mode of operation. However, the current market technologies, such as electrochromic, polymer dispersed liquid crystal, and suspended particle devices are expensive and suffer from solar absorption, poor transmittance modulation, and in some cases, continuous power consumption. The authors of this paper present a novel optofluidic smart glass prototype capable of modulating visible light transmittance from 8% to 85%.

  18. Development of a prototype graphic simulation program for severe accident training

    International Nuclear Information System (INIS)

    Kim, Ko Ryu; Jeong, Kwang Sub; Ha, Jae Joo

    2000-05-01

    This is a report of the development process and related technologies of severe accident graphic simulators, required in industrial severe accident management and training. Here, we say 'a severe accident graphic simulator' as a graphics add-in system to existing calculation codes, which can show the severe accident phenomena dynamically on computer screens and therefore which can supplement one of main defects of existing calculation codes. With graphic simulators it is fairly easy to see the total behavior of nuclear power plants, where it was very difficult to see only from partial variable numerical information. Moreover, the fast processing and control feature of a graphic simulator can give some opportunities of predicting the severe accident advancement among several possibilities, to one who is not an expert. Utilizing graphic simulators' we expect operators' and TSC members' physical phenomena understanding enhancement from the realistic dynamic behavior of plants. We also expect that severe accident training course can gain better training effects using graphic simulator's control functions and predicting capabilities, and therefore we expect that graphic simulators will be effective decision-aids tools both in sever accident training course and in real severe accident situations. With these in mind, we have developed a prototype graphic simulator having surveyed related technologies, and from this development experiences we have inspected the possibility to build a severe accident graphic simulator. The prototype graphic simulator is developed under IBM PC WinNT environments and is suited to Uljin 3and4 nuclear power plant. When supplied with adequate severe accident scenario as an input, the prototype can provide graphical simulations of plant safety systems' dynamic behaviors. The prototype is composed of several different modules, which are phenomena display module, MELCOR data interface module and graphic database interface module. Main functions of

  19. Characterization of a high-energy in-line phase contrast tomosynthesis prototype.

    Science.gov (United States)

    Wu, Di; Yan, Aimin; Li, Yuhua; Wong, Molly D; Zheng, Bin; Wu, Xizeng; Liu, Hong

    2015-05-01

    prototype. In addition, the PAD-based method of phase retrieval was combined with tomosynthesis imaging for the first time, which demonstrated its capability in significantly improving the contrast-to-noise ratios in the images.

  20. New layer-based imaging and rapid prototyping techniques for computer-aided design and manufacture of custom dental restoration.

    Science.gov (United States)

    Lee, M-Y; Chang, C-C; Ku, Y C

    2008-01-01

    Fixed dental restoration by conventional methods greatly relies on the skill and experience of the dental technician. The quality and accuracy of the final product depends mostly on the technician's subjective judgment. In addition, the traditional manual operation involves many complex procedures, and is a time-consuming and labour-intensive job. Most importantly, no quantitative design and manufacturing information is preserved for future retrieval. In this paper, a new device for scanning the dental profile and reconstructing 3D digital information of a dental model based on a layer-based imaging technique, called abrasive computer tomography (ACT) was designed in-house and proposed for the design of custom dental restoration. The fixed partial dental restoration was then produced by rapid prototyping (RP) and computer numerical control (CNC) machining methods based on the ACT scanned digital information. A force feedback sculptor (FreeForm system, Sensible Technologies, Inc., Cambridge MA, USA), which comprises 3D Touch technology, was applied to modify the morphology and design of the fixed dental restoration. In addition, a comparison of conventional manual operation and digital manufacture using both RP and CNC machining technologies for fixed dental restoration production is presented. Finally, a digital custom fixed restoration manufacturing protocol integrating proposed layer-based dental profile scanning, computer-aided design, 3D force feedback feature modification and advanced fixed restoration manufacturing techniques is illustrated. The proposed method provides solid evidence that computer-aided design and manufacturing technologies may become a new avenue for custom-made fixed restoration design, analysis, and production in the 21st century.

  1. Rapid Prototyping of a Text Mining Application for Cryptocurrency Market Intelligence

    OpenAIRE

    Laskowski, Marek; Kim, Henry M.

    2016-01-01

    Blockchain represents a technology for establishing a shared, immutable version of the truth between a network of participants that do not trust one another, and therefore has the potential to disrupt any financial or other industries that rely on third-parties to establish trust. Recent trends in computing including: prevalence of Free and Open Source Software (FOSS); easy access to High Performance Computing (HPC i.e. 'The Cloud'); and increasingly advanced analytics capabilities such as Na...

  2. Outperforming hummingbirds’ load-lifting capability with a lightweight hummingbird-like flapping-wing mechanism

    Directory of Open Access Journals (Sweden)

    Frederik Leys

    2016-08-01

    Full Text Available The stroke-cam flapping mechanism presented in this paper closely mimics the wing motion of a hovering Rufous hummingbird. It is the only lightweight hummingbird-sized flapping mechanism which generates a harmonic wing stroke with both a high flapping frequency and a large stroke amplitude. Experiments on a lightweight prototype of this stroke-cam mechanism on a 50 mm-long wing demonstrate that a harmonic stroke motion is generated with a peak-to-peak stroke amplitude of 175° at a flapping frequency of 40 Hz. It generated a mass lifting capability of 5.1 g, which is largely sufficient to lift the prototype's mass of 3.39 g and larger than the mass-lifting capability of a Rufous hummingbird. The motor mass of a hummingbird-like robot which drives the stroke-cam mechanism is considerably larger (about five times than the muscle mass of a hummingbird with comparable load-lifting capability. This paper presents a flapping wing nano aerial vehicle which is designed to possess the same lift- and thrust-generating principles of the Rufous hummingbird. The application is indoor flight. We give an overview of the wing kinematics and some specifications which should be met to develop an artificial wing, and also describe the applications of these in the mechanism which has been developed in this work.

  3. Prototyping in theory and in practice

    DEFF Research Database (Denmark)

    Yu, Fei; Brem, Alexander; Pasinell, Michele

    2018-01-01

    and functions of a prototype and needed to meet specific goals in order to push the process forward. Designers, on the other hand, used prototypes to investigate the design space for new possibilities, and were more open to a variety of prototyping materials and tools, especially for low-fidelity prototypes...

  4. SU-F-J-196: A Prototype System for Portal Imaging for Intensity Modulated Neutron Therapy

    Energy Technology Data Exchange (ETDEWEB)

    St James, S; Argento, D; DeWitt, D; Miyaoka, R; Stewart, R [University of Washington, Seattle, WA (United States); Moffitt, G [University of Utah, Salt Lake City, UT (United States)

    2016-06-15

    Purpose: Fast neutron therapy is offered at the University of Washington Medical Center for treatment of selected cancers. The hardware and control systems of the UW Clinical Neutron Therapy System are undergoing upgrades to enable delivery of IMNT. To clinically implement IMNT, dose verification tools need to be developed. We propose a portal imaging system that relies on the creation of positron emitting isotopes ({sup 11}C and {sup 15}O) through (n, 2n) reactions with a PMMA plate placed below the patient. After field delivery, the plate is retrieved from the vault and imaged using a reader that detects the annihilation photons. The pattern of activity produced in the plate provides information to reconstruct the neutron fluence map that can be compared to fluence maps from Monte Carlo (MCNP) simulations to verify treatment delivery. We have previously performed Monte Carlo simulations of the portal imaging system (GATE simulations) and the beam line (MCNP simulations). In this work, initial measurements using a prototype system are presented. Methods: Custom electronics were developed for BGO detectors read out with photomultiplier tubes (previous generation PET detectors from a CTI ECAT 953 scanner). Two detectors were placed in coincidence, with a detector separation of 2 cm. Custom software was developed to create the crystal look up tables and perform a limited angle planar reconstruction with a stochastic normalization. To test the initial capabilities of the system, PMMA squares were irradiated with neutrons at a depth of 1.5 cm and read out using the prototype system. Doses ranging from 10–200 cGy were delivered. Results: Using the prototype system, dose differences in the therapeutic range could be determined. Conclusion: The prototype portal imaging system is capable of detecting neutron doses as low as 10–50 cGy and shows great promise as a patient QA tool for IMNT.

  5. Mechanical Prototyping and Manufacturing Internship

    Science.gov (United States)

    Grenfell, Peter

    2016-01-01

    The internship was located at the Johnson Space Center (JSC) Innovation Design Center (IDC), which is a facility where the JSC workforce can meet and conduct hands-on innovative design, fabrication, evaluation, and testing of ideas and concepts relevant to NASA's mission. The tasks of the internship included mechanical prototyping design and manufacturing projects in service of research and development as well as assisting the users of the IDC in completing their manufacturing projects. The first project was to manufacture hatch mechanisms for a team in the Systems Engineering and Project Advancement Program (SETMAP) hexacopter competition. These mechanisms were intended to improve the performance of the servomotors and offer an access point that would also seal to prevent cross-contamination. I also assisted other teams as they were constructing and modifying their hexacopters. The success of this competition demonstrated a proof of concept for aerial reconnaissance and sample return to be potentially used in future NASA missions. I also worked with Dr. Kumar Krishen to prototype an improved thermos and a novel, portable solar array. Computer-aided design (CAD) software was used to model the parts for both of these projects. Then, 3D printing as well as conventional techniques were used to produce the parts. These prototypes were then subjected to trials to determine the success of the designs. The solar array is intended to work in a cluster that is easy to set up and take down and doesn't require powered servomechanisms. It could be used terrestrially in areas not serviced by power grids. Both projects improve planetary exploration capabilities to future astronauts. Other projects included manufacturing custom rail brackets for EG-2, assisting engineers working on underwater instrument and tool cases for the NEEMO project, and helping to create mock-up parts for Space Center Houston. The use of the IDC enabled efficient completion of these projects at

  6. Effects of carbon fibres on the life cycle assessment of additively manufactured injection moulding inserts for rapid prototyping

    DEFF Research Database (Denmark)

    Hofstätter, Thomas; Bey, Niki; Mischkot, Michael

    2017-01-01

    properties and lifetime. The additively manufactured inserts are compared to the standard materials steel, aluminium and brass. The investigated part of the production and prototyping phase considers the insert itself, the moulded part, and resulting waste material of the injection moulding process....

  7. High Heat Flux Test of the ITER FW Semi-prototype Mockups

    International Nuclear Information System (INIS)

    Bae, Young Dug; Lee, Dong Won; Kim, Suk Kwon; Yoon, Jae Sung; Hong, Bong Guen

    2010-01-01

    As a procurement party of the ITER (International Thermonuclear Experimental Reactor) blanket project, we have to pass the qualification program which comprises two distinct phases; Phases 1 is about qualifying joining techniques, and phase 2 covers production scaled up component which is so called 'semi-prototype' and the enhanced heat flux qualification. We have constructed the FWQMs (First Wall Qualification Mockups) and already passed the qualification thermal fatigue tests organized by the IO (ITER Organization). The tests were performed at the EB-1200 in the USA and at the BESTH /JUDITH-2 in the EU. For the phase 2 qualification, the semi-prototype design will be provided by the IO. Even though the design has not fixed because the generic design of the first wall is not fixed, it shall comprise a minimum of 3 full length pairs of first wall fingers. We designed and fabricated two semi-prototype mockups which have a full length pair of first wall finger. The two mockups were designed to have different types of the cooling channels; one has a plain rectangular cross-section and the other has a hypervapotron type cooling channel. In order to compare the cooling capability of the two types, we performed high heat flux tests of the two mockups at the KoHLT-2

  8. EBR-2 [Experimental Breeder Reactor-2], IFR [Integral Fast Reactor] prototype testing programs

    International Nuclear Information System (INIS)

    Lehto, W.K.; Sackett, J.I.; Lindsay, R.W.; Planchon, H.P.; Lambert, J.D.B.

    1990-01-01

    The Experimental Breeder Reactor-2 (EBR-2) is a sodium cooled power reactor supplying about 20 MWe to the Idaho National Engineering Laboratory (INEL) grid and, in addition, is the key component in the development of the Integral Fast Reactor (IFR). EBR-2's testing capability is extensive and has seen four major phases: (1) demonstration of LMFBR power plant feasibility, (2) irradiation testing for fuel and material development. (3) testing the off-normal performance of fuel and plant systems and (4) operation as the IFR prototype, developing and demonstrating the IFR technology associated with fuel and plant design. Specific programs being carried out in support of the IFR include advanced fuels and materials development and component testing. This paper discusses EBR-2 as the IFR prototype and the associated testing programs. 29 refs

  9. Mobile prototyping with Axure 7

    CERN Document Server

    Hacker, Will

    2013-01-01

    This book is a step-by-step tutorial which includes hands-on examples and downloadable Axure files to get you started with mobile prototyping immediately. You will learn how to develop an application from scratch, and will be guided through each and every step.If you are a mobile-centric developer/designer, or someone who would like to take their Axure prototyping skills to the next level and start designing and testing mobile prototypes, this book is ideal for you. You should be familiar with prototyping and Axure specifically, before you read this book.

  10. Rapid prototyping for tissue-engineered bone scaffold by 3D printing and biocompatibility study.

    Science.gov (United States)

    He, Hui-Yu; Zhang, Jia-Yu; Mi, Xue; Hu, Yang; Gu, Xiao-Yu

    2015-01-01

    The prototyping of tissue-engineered bone scaffold (calcined goat spongy bone-biphasic ceramic composite/PVA gel) by 3D printing was performed, and the biocompatibility of the fabricated bone scaffold was studied. Pre-designed STL file was imported into the GXYZ303010-XYLE 3D printing system, and the tissue-engineered bone scaffold was fabricated by 3D printing using gel extrusion. Rabbit bone marrow stromal cells (BMSCs) were cultured in vitro and then inoculated to the sterilized bone scaffold obtained by 3D printing. The growth of rabbit BMSCs on the bone scaffold was observed under the scanning electron microscope (SEM). The effect of the tissue-engineered bone scaffold on the proliferation and differentiation of rabbit BMSCs using MTT assay. Universal testing machine was adopted to test the tensile strength of the bone scaffold. The leachate of the bone scaffold was prepared and injected into the New Zealand rabbits. Cytotoxicity test, acute toxicity test, pyrogenic test and intracutaneous stimulation test were performed to assess the biocompatibility of the bone scaffold. Bone scaffold manufactured by 3D printing had uniform pore size with the porosity of about 68.3%. The pores were well interconnected, and the bone scaffold showed excellent mechanical property. Rabbit BMSCs grew and proliferated on the surface of the bone scaffold after adherence. MTT assay indicated that the proliferation and differentiation of rabbit BMSCs on the bone scaffold did not differ significantly from that of the cells in the control. In vivo experiments proved that the bone scaffold fabricated by 3D printing had no acute toxicity, pyrogenic reaction or stimulation. Bone scaffold manufactured by 3D printing allows the rabbit BMSCs to adhere, grow and proliferate and exhibits excellent biomechanical property and high biocompatibility. 3D printing has a good application prospect in the prototyping of tissue-engineered bone scaffold.

  11. Prototype-Incorporated Emotional Neural Network.

    Science.gov (United States)

    Oyedotun, Oyebade K; Khashman, Adnan

    2017-08-15

    Artificial neural networks (ANNs) aim to simulate the biological neural activities. Interestingly, many ''engineering'' prospects in ANN have relied on motivations from cognition and psychology studies. So far, two important learning theories that have been subject of active research are the prototype and adaptive learning theories. The learning rules employed for ANNs can be related to adaptive learning theory, where several examples of the different classes in a task are supplied to the network for adjusting internal parameters. Conversely, the prototype-learning theory uses prototypes (representative examples); usually, one prototype per class of the different classes contained in the task. These prototypes are supplied for systematic matching with new examples so that class association can be achieved. In this paper, we propose and implement a novel neural network algorithm based on modifying the emotional neural network (EmNN) model to unify the prototype- and adaptive-learning theories. We refer to our new model as ``prototype-incorporated EmNN''. Furthermore, we apply the proposed model to two real-life challenging tasks, namely, static hand-gesture recognition and face recognition, and compare the result to those obtained using the popular back-propagation neural network (BPNN), emotional BPNN (EmNN), deep networks, an exemplar classification model, and k-nearest neighbor.

  12. The development of a prototype level-three interoperable catalog system

    Science.gov (United States)

    Hood, Carroll A.; Howie, Randy; Verhanovitz, Rich

    1993-08-01

    The development of a level-three interoperable catalog system is defined by a new paradigm for metadata access. The old paradigm is characterized by a hierarchy of metadata layers, the transfer of control to target systems, and the requirement for the user to be familiar with the syntax and data dictionaries of several catalog system elements. Attributes of the new paradigm are exactly orthogonal: the directory and inventories are peer entities, there is a single user interface, and the system manages the complexity of interacting transparently with remote elements. We have designed and implemented a prototype level-three interoperable catalog system based on the new paradigm. Through a single intelligent interface, users can interoperably access a master directory, inventories for selected satellite datasets, and an in situ meteorological dataset inventory. This paper describes the development of the prototype system and three of the formidable challenges that were addressed in the process. The first involved the interoperable integration of satellite and in situ inventories, which to our knowledge, has never been operationally demonstrated. The second was the development of a search strategy for orbital and suborbital granules which preserves the capability to identify temporally or spatially coincident subsets between them. The third involved establishing a method of incorporating inventory-specific search criteria into user queries. We are working closely with selected science data users to obtain feedback on the system's design and performance. The lessons learned from this prototype will help direct future development efforts. Distributed data systems of the 1990s such as EOSDIS and the Global Change Data and Information System (GCDIS) will be able to build on this prototype.

  13. Fuzzy AHP Analysis on Enterprises’ Independent Innovation Capability Evaluation

    Science.gov (United States)

    Zhu, Yu; Lei, Huai-ying

    Independent innovation has become a key factor in the rapid and healthy development of the enterprises. Therefore, an effective and reasonable comprehensive evaluation on the independent innovation capability of the businesses is especially important. This paper applies fuzzy AHP in the evaluation of the independent innovation capability of the businesses, and validates the rationality and feasibility of the evaluation methods and the indicators.

  14. Prototype Effect and the Persuasiveness of Generalizations.

    Science.gov (United States)

    Dahlman, Christian; Sarwar, Farhan; Bååth, Rasmus; Wahlberg, Lena; Sikström, Sverker

    An argument that makes use of a generalization activates the prototype for the category used in the generalization. We conducted two experiments that investigated how the activation of the prototype affects the persuasiveness of the argument. The results of the experiments suggest that the features of the prototype overshadow and partly overwrite the actual facts of the case. The case is, to some extent, judged as if it had the features of the prototype instead of the features it actually has. This prototype effect increases the persuasiveness of the argument in situations where the audience finds the judgment more warranted for the prototype than for the actual case (positive prototype effect), but decreases persuasiveness in situations where the audience finds the judgment less warranted for the prototype than for the actual case (negative prototype effect).

  15. Development of a decision aid for cardiopulmonary resuscitation and invasive mechanical ventilation in the intensive care unit employing user-centered design and a wiki platform for rapid prototyping.

    Science.gov (United States)

    Plaisance, Ariane; Witteman, Holly O; LeBlanc, Annie; Kryworuchko, Jennifer; Heyland, Daren Keith; Ebell, Mark H; Blair, Louisa; Tapp, Diane; Dupuis, Audrey; Lavoie-Bérard, Carole-Anne; McGinn, Carrie Anna; Légaré, France; Archambault, Patrick Michel

    2018-01-01

    Upon admission to an intensive care unit (ICU), all patients should discuss their goals of care and express their wishes concerning life-sustaining interventions (e.g., cardiopulmonary resuscitation (CPR)). Without such discussions, interventions that prolong life at the cost of decreasing its quality may be used without appropriate guidance from patients. To adapt an existing decision aid about CPR to create a wiki-based decision aid individually adapted to each patient's risk factors; and to document the use of a wiki platform for this purpose. We conducted three weeks of ethnographic observation in our ICU to observe intensivists and patients discussing goals of care and to identify their needs regarding decision making. We interviewed intensivists individually. Then we conducted three rounds of rapid prototyping involving 15 patients and 11 health professionals. We recorded and analyzed all discussions, interviews and comments, and collected sociodemographic data. Using a wiki, a website that allows multiple users to contribute or edit content, we adapted the decision aid accordingly and added the Good Outcome Following Attempted Resuscitation (GO-FAR) prediction rule calculator. We added discussion of invasive mechanical ventilation. The final decision aid comprises values clarification, risks and benefits of CPR and invasive mechanical ventilation, statistics about CPR, and a synthesis section. We added the GO-FAR prediction calculator as an online adjunct to the decision aid. Although three rounds of rapid prototyping simplified the information in the decision aid, 60% (n = 3/5) of the patients involved in the last cycle still did not understand its purpose. Wikis and user-centered design can be used to adapt decision aids to users' needs and local contexts. Our wiki platform allows other centers to adapt our tools, reducing duplication and accelerating scale-up. Physicians need training in shared decision making skills about goals of care and in using the

  16. Development of a decision aid for cardiopulmonary resuscitation and invasive mechanical ventilation in the intensive care unit employing user-centered design and a wiki platform for rapid prototyping.

    Directory of Open Access Journals (Sweden)

    Ariane Plaisance

    Full Text Available Upon admission to an intensive care unit (ICU, all patients should discuss their goals of care and express their wishes concerning life-sustaining interventions (e.g., cardiopulmonary resuscitation (CPR. Without such discussions, interventions that prolong life at the cost of decreasing its quality may be used without appropriate guidance from patients.To adapt an existing decision aid about CPR to create a wiki-based decision aid individually adapted to each patient's risk factors; and to document the use of a wiki platform for this purpose.We conducted three weeks of ethnographic observation in our ICU to observe intensivists and patients discussing goals of care and to identify their needs regarding decision making. We interviewed intensivists individually. Then we conducted three rounds of rapid prototyping involving 15 patients and 11 health professionals. We recorded and analyzed all discussions, interviews and comments, and collected sociodemographic data. Using a wiki, a website that allows multiple users to contribute or edit content, we adapted the decision aid accordingly and added the Good Outcome Following Attempted Resuscitation (GO-FAR prediction rule calculator.We added discussion of invasive mechanical ventilation. The final decision aid comprises values clarification, risks and benefits of CPR and invasive mechanical ventilation, statistics about CPR, and a synthesis section. We added the GO-FAR prediction calculator as an online adjunct to the decision aid. Although three rounds of rapid prototyping simplified the information in the decision aid, 60% (n = 3/5 of the patients involved in the last cycle still did not understand its purpose.Wikis and user-centered design can be used to adapt decision aids to users' needs and local contexts. Our wiki platform allows other centers to adapt our tools, reducing duplication and accelerating scale-up. Physicians need training in shared decision making skills about goals of care and in

  17. Use of a prototype pulse oximeter for time series analysis of heart rate variability

    Science.gov (United States)

    González, Erika; López, Jehú; Hautefeuille, Mathieu; Velázquez, Víctor; Del Moral, Jésica

    2015-05-01

    This work presents the development of a low cost pulse oximeter prototype consisting of pulsed red and infrared commercial LEDs and a broad spectral photodetector used to register time series of heart rate and oxygen saturation of blood. This platform, besides providing these values, like any other pulse oximeter, processes the signals to compute a power spectrum analysis of the patient heart rate variability in real time and, additionally, the device allows access to all raw and analyzed data if databases construction is required or another kind of further analysis is desired. Since the prototype is capable of acquiring data for long periods of time, it is suitable for collecting data in real life activities, enabling the development of future wearable applications.

  18. Three-Dimensional Printing of Vitrification Loop Prototypes for Aquatic Species.

    Science.gov (United States)

    Tiersch, Nolan J; Childress, William M; Tiersch, Terrence R

    2018-05-16

    Vitrification is a method of cryopreservation that freezes samples rapidly, while forming an amorphous solid ("glass"), typically in small (μL) volumes. The goal of this project was to create, by three-dimensional (3D) printing, open vitrification devices based on an elliptical loop that could be efficiently used and stored. Vitrification efforts can benefit from the application of 3D printing, and to begin integration of this technology, we addressed four main variables: thermoplastic filament type, loop length, loop height, and method of loading. Our objectives were to: (1) design vitrification loops with varied dimensions; (2) print prototype loops for testing; (3) evaluate loading methods for the devices; and (4) classify vitrification responses to multiple device configurations. The various configurations were designed digitally using 3D CAD (Computer Aided Design) software, and prototype devices were produced with MakerBot ® 3D printers. The thermoplastic filaments used to produce devices were acrylonitrile butadiene styrene (ABS) and polylactic acid (PLA). Vitrification devices were characterized by the film volumes formed with different methods of loading (pipetting or submersion). Frozen films were classified to determine vitrification quality: zero (opaque, or abundant crystalline ice formation); one (translucent, or partial vitrification), or two (transparent, or substantial vitrification, glass). A published vitrification solution was used to conduct experiments. Loading by pipetting formed frozen films more reliably than by submersion, but submersion yielded fewer filling problems and was more rapid. The loop designs that yielded the highest levels of vitrification enabled rapid transfer of heat, and most often were characterized as being longer and consisting of fewer layers (height). 3D printing can assist standardization of vitrification methods and research, yet can also provide the ability to quickly design and fabricate custom devices when

  19. Project management strategies for prototyping breakdowns

    DEFF Research Database (Denmark)

    Granlien, Maren Sander; Pries-Heje, Jan; Baskerville, Richard

    2009-01-01

    , managing the explorative and iterative aspects of prototyping projects is not a trivial task. We examine the managerial challenges in a small scale prototyping project in the Danish healthcare sector where a prototype breakdown and project escalation occurs. From this study we derive a framework...... of strategies for coping with escalation in troubled prototyping projects; the framework is based on project management triangle theory and is useful when considering how to manage prototype breakdown and escalation. All strategies were applied in the project case at different points in time. The strategies led...

  20. Rapid development of medical imaging tools with open-source libraries.

    Science.gov (United States)

    Caban, Jesus J; Joshi, Alark; Nagy, Paul

    2007-11-01

    Rapid prototyping is an important element in researching new imaging analysis techniques and developing custom medical applications. In the last ten years, the open source community and the number of open source libraries and freely available frameworks for biomedical research have grown significantly. What they offer are now considered standards in medical image analysis, computer-aided diagnosis, and medical visualization. A cursory review of the peer-reviewed literature in imaging informatics (indeed, in almost any information technology-dependent scientific discipline) indicates the current reliance on open source libraries to accelerate development and validation of processes and techniques. In this survey paper, we review and compare a few of the most successful open source libraries and frameworks for medical application development. Our dual intentions are to provide evidence that these approaches already constitute a vital and essential part of medical image analysis, diagnosis, and visualization and to motivate the reader to use open source libraries and software for rapid prototyping of medical applications and tools.