WorldWideScience

Sample records for rapid numerical procedure

  1. Numerical modelling of rapid solidification

    DEFF Research Database (Denmark)

    Pryds, Nini; Hattel, Jesper Henri

    1997-01-01

    A mathematical model of the melt spinning process has been developed based on the control-volume finite-difference method. The model avoids some of the limitations of the previous models, for example including the effect of the wheel in the heat how calculations and the temperature dependence......, for example the recalescence characteristic, was investigated. The results of the model showed that the effect of heating of the wheel is difficult to prevent even for a wheel material of high conductivity. The recalescence effect was found to be influenced by the wheel surface temperature and to decrease...... with increasing thermal conductivity of the wheel. The observed increase in the wheel surface temperature suggests the importance of including the wheel in the numerical calculations, especially for a wheel made of a low-conductive material...

  2. Multigrade Teaching Rapid Appraisal Procedure.

    Science.gov (United States)

    Nielsen, Dean

    Multigrade classes have been recognized as part of elementary education for many years, but their special needs have been largely ignored. This manual focuses on the survey research that should predate the design of instructional management strategies in multigrade classrooms. It describes rapid and reliable ways to collect information about the…

  3. Numerical Procedure for Optimizing Dye-Sensitized Solar Cells

    Directory of Open Access Journals (Sweden)

    Mihai Razvan Mitroi

    2014-01-01

    Full Text Available We propose a numerical procedure consisting of a simplified physical model and a numerical method with the aim of optimizing the performance parameters of dye-sensitized solar cells (DSSCs. We calculate the real rate of absorbed photons (in the dye spectral range Grealx by introducing a factor β<1 in order to simplify the light absorption and reflection on TCO electrode. We consider the electrical transport to be purely diffusive and the recombination process only to occur between electrons from the TiO2 conduction band and anions from the electrolyte. The used numerical method permits solving the system of differential equations resulting from the physical model. We apply the proposed numerical procedure on a classical DSSC based on Ruthenium dye in order to validate it. For this, we simulate the J-V characteristics and calculate the main parameters: short-circuit current density Jsc, open circuit voltage Voc, fill factor FF, and power conversion efficiency η. We analyze the influence of the nature of semiconductor (TiO2 and dye and also the influence of different technological parameters on the performance parameters of DSSCs. The obtained results show that the proposed numerical procedure is suitable for developing a numerical simulation platform for improving the DSSCs performance by choosing the optimal parameters.

  4. Biocytin: a neuronal tracer compatible with rapid decalcification procedures.

    Science.gov (United States)

    Wirsig-Wiechmann, C R

    1994-03-01

    The compatibility of neuronal tract-tracing and decalcification procedures was examined in salamander nasal chemosensory systems. Biocytin, but not horseradish peroxidase, retained its labeling capacity following rapid decalcification of the cranial bone. The combination of biocytin tract-tracing and decalcification procedures allows the visualization of labeled neurons and/or their projections within bony regions of intact specimens.

  5. Numerical comparison between different strength after impact test procedures

    Directory of Open Access Journals (Sweden)

    Klaus M.

    2010-06-01

    Full Text Available Different procedures are established to investigate the residual properties of sandwich panels after impact damage. Two used procedures for the testing of this properties are compression after impact (CAI and 4-point bending. In this paper a numerical procedure is presented for a first prediction of the behaviour of pre-damaged sandwich specimens under different boundary conditions (or testing procedures. A sequence of impact experiments using a drop tower is performed to assess the damage tolerance of sandwich panels with aramid paper foldcores and CFRP skins. The tested impact energy range allowed to investigate a variety of damage scenarios from barely visible damages (BVID to fibre fractures in all plies of the impacted face sheet. Additionally 4-point bending tests are performed with the panels previously damaged by impact loadings to assess the residual bending strength of these samples. The developed numerical procedure is used to reproduce these experiments (the impact as well as the 4-point bending tests. Also the same procedure is employed in an attempt to predict the behaviour of samples with the same build-up in simulated compression after impact tests.

  6. Rapid installation of numerical models in multiple parent codes

    Energy Technology Data Exchange (ETDEWEB)

    Brannon, R.M.; Wong, M.K.

    1996-10-01

    A set of``model interface guidelines``, called MIG, is offered as a means to more rapidly install numerical models (such as stress-strain laws) into any parent code (hydrocode, finite element code, etc.) without having to modify the model subroutines. The model developer (who creates the model package in compliance with the guidelines) specifies the model`s input and storage requirements in a standardized way. For portability, database management (such as saving user inputs and field variables) is handled by the parent code. To date, NUG has proved viable in beta installations of several diverse models in vectorized and parallel codes written in different computer languages. A NUG-compliant model can be installed in different codes without modifying the model`s subroutines. By maintaining one model for many codes, MIG facilitates code-to-code comparisons and reduces duplication of effort potentially reducing the cost of installing and sharing models.

  7. A Simple, Rapid and Inexpensive Procedure to Distinguish Amino ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 3. A Simple, Rapid and Inexpensive Procedure to Distinguish Amino Acids and their Esters. B Ramachandra ... Author Affiliations. B Ramachandra Murty1. Department of Biochemistry PSG College of Arts and Science Coimbatore 641 014, India.

  8. Numerical Simulations of Thermal Convection in Rapidly Rotating Spherical Shell

    Energy Technology Data Exchange (ETDEWEB)

    Nenkov, Constantine; Peltier, Richard, E-mail: nenkov@atmosp.physics.utoronto.ca, E-mail: peltier@atmosp.physics.utoronto.ca [Department of Physics, University of Toronto Toronto, Ontario, M5S 1A7 (Canada)

    2010-11-01

    We present a novel numerical model used to simulate convection in the atmospheres of the Gas Giant planets Jupiter and Saturn. Nonlinear, three-dimensional, time-dependant solutions of the anelastic hydrodynamic equations are presented for a stratified, rotating spherical fluid shell heated from below. This new model is specified in terms of a grid-point based methodology which employs a hierarchy of tessellations of the regular icosahedron onto the sphere through the process of recurrent dyadic refinements of the spherical surface. We describe discretizations of the governing equations in which all calculations are performed in Cartesian coordinates in the local neighborhoods of the almost uniform icosahedral grid, a methodology which avoids the potential mathematical and numerical difficulties associated with the pole problem in spherical geometry. Using this methodology we have built our model in primitive equations formulation, whereas the three-dimensional vector velocity field and temperature are directly advanced in time. We show results of thermal convection in rapidly rotating spherical shell which leads to the formation of well pronounced prograde zonal jets at the equator, results which previous experiments with two-dimensional models in the limit of freely evolving turbulence were not able to achieve.

  9. An operational procedure for rapid flood risk assessment in Europe

    Science.gov (United States)

    Dottori, Francesco; Kalas, Milan; Salamon, Peter; Bianchi, Alessandra; Alfieri, Lorenzo; Feyen, Luc

    2017-07-01

    The development of methods for rapid flood mapping and risk assessment is a key step to increase the usefulness of flood early warning systems and is crucial for effective emergency response and flood impact mitigation. Currently, flood early warning systems rarely include real-time components to assess potential impacts generated by forecasted flood events. To overcome this limitation, this study describes the benchmarking of an operational procedure for rapid flood risk assessment based on predictions issued by the European Flood Awareness System (EFAS). Daily streamflow forecasts produced for major European river networks are translated into event-based flood hazard maps using a large map catalogue derived from high-resolution hydrodynamic simulations. Flood hazard maps are then combined with exposure and vulnerability information, and the impacts of the forecasted flood events are evaluated in terms of flood-prone areas, economic damage and affected population, infrastructures and cities.An extensive testing of the operational procedure has been carried out by analysing the catastrophic floods of May 2014 in Bosnia-Herzegovina, Croatia and Serbia. The reliability of the flood mapping methodology is tested against satellite-based and report-based flood extent data, while modelled estimates of economic damage and affected population are compared against ground-based estimations. Finally, we evaluate the skill of risk estimates derived from EFAS flood forecasts with different lead times and combinations of probabilistic forecasts. Results highlight the potential of the real-time operational procedure in helping emergency response and management.

  10. Application of laser measuring, numerical simulation and rapid prototyping to titanium dental castings.

    Science.gov (United States)

    Wu, M; Tinschert, J; Augthun, M; Wagner, I; Schädlich-Stubenrauch, J; Sahm, P R; Spiekermann, H

    2001-03-01

    This paper describes a method of making titanium dental crowns by means of integrating laser measuring, numerical simulation and rapid prototype (RP) manufacture of wax patterns for the investment casting process. Four real tooth crowns (FDI No. 24, 25, 26, 27) were measured by means of 3D laser scanning. The laser digitized geometry of the crowns was processed and converted into standard CAD models in STL format, which is used by RP systems and numerical simulation software. Commercial software (MAGMASOFT) was used to simulate the casting process and optimize the runner and gating system (sprue) design. RP crowns were 'printed' directly on a ModelMaker II 3D Plotting System. A silicone negative mold (soft tool) was made from the RP crowns, then more than hundreds wax crowns were duplicated. The duplicated crowns were joined to the optimized runner and gating system. By using the investment casting process 20-25 replicas of each crown were made on a centrifugal casting machine. All castings were examined for porosity by X-ray radiographs. By using the integrated scanning, simulation, RP pattern and casting procedure, cast crowns, free of porosity, with excellent functional contour and a smooth surface finish, were obtained from the first casting trial. The coupling of laser digitizing and RP indicates a potential to replace the traditional 'impression taking and waxing' procedure in dental laboratory, with the quality of the cast titanium prostheses also being improved by using the numerically optimized runner and gating system design.

  11. An operational procedure for rapid flood risk assessment in Europe

    Directory of Open Access Journals (Sweden)

    F. Dottori

    2017-07-01

    Full Text Available The development of methods for rapid flood mapping and risk assessment is a key step to increase the usefulness of flood early warning systems and is crucial for effective emergency response and flood impact mitigation. Currently, flood early warning systems rarely include real-time components to assess potential impacts generated by forecasted flood events. To overcome this limitation, this study describes the benchmarking of an operational procedure for rapid flood risk assessment based on predictions issued by the European Flood Awareness System (EFAS. Daily streamflow forecasts produced for major European river networks are translated into event-based flood hazard maps using a large map catalogue derived from high-resolution hydrodynamic simulations. Flood hazard maps are then combined with exposure and vulnerability information, and the impacts of the forecasted flood events are evaluated in terms of flood-prone areas, economic damage and affected population, infrastructures and cities.An extensive testing of the operational procedure has been carried out by analysing the catastrophic floods of May 2014 in Bosnia–Herzegovina, Croatia and Serbia. The reliability of the flood mapping methodology is tested against satellite-based and report-based flood extent data, while modelled estimates of economic damage and affected population are compared against ground-based estimations. Finally, we evaluate the skill of risk estimates derived from EFAS flood forecasts with different lead times and combinations of probabilistic forecasts. Results highlight the potential of the real-time operational procedure in helping emergency response and management.

  12. Procedural Modeling for Rapid-Prototyping of Multiple Building Phases

    Science.gov (United States)

    Saldana, M.; Johanson, C.

    2013-02-01

    RomeLab is a multidisciplinary working group at UCLA that uses the city of Rome as a laboratory for the exploration of research approaches and dissemination practices centered on the intersection of space and time in antiquity. In this paper we present a multiplatform workflow for the rapid-prototyping of historical cityscapes through the use of geographic information systems, procedural modeling, and interactive game development. Our workflow begins by aggregating archaeological data in a GIS database. Next, 3D building models are generated from the ArcMap shapefiles in Esri CityEngine using procedural modeling techniques. A GIS-based terrain model is also adjusted in CityEngine to fit the building elevations. Finally, the terrain and city models are combined in Unity, a game engine which we used to produce web-based interactive environments which are linked to the GIS data using keyhole markup language (KML). The goal of our workflow is to demonstrate that knowledge generated within a first-person virtual world experience can inform the evaluation of data derived from textual and archaeological sources, and vice versa.

  13. Asymptotic and Numerical Methods for Rapidly Rotating Buoyant Flow

    Science.gov (United States)

    Grooms, Ian G.

    This thesis documents three investigations carried out in pursuance of a doctoral degree in applied mathematics at the University of Colorado (Boulder). The first investigation concerns the properties of rotating Rayleigh-Benard convection -- thermal convection in a rotating infinite plane layer between two constant-temperature boundaries. It is noted that in certain parameter regimes convective Taylor columns appear which dominate the dynamics, and a semi-analytical model of these is presented. Investigation of the columns and of various other properties of the flow is ongoing. The second investigation concerns the interactions between planetary-scale and mesoscale dynamics in the oceans. Using multiple-scale asymptotics the possible connections between planetary geostrophic and quasigeostrophic dynamics are investigated, and three different systems of coupled equations are derived. Possible use of these equations in conjunction with the method of superparameterization, and extension of the asymptotic methods to the interactions between mesoscale and submesoscale dynamics is ongoing. The third investigation concerns the linear stability properties of semi-implicit methods for the numerical integration of ordinary differential equations, focusing in particular on the linear stability of IMEX (Implicit-Explicit) methods and exponential integrators applied to systems of ordinary differential equations arising in the numerical solution of spatially discretized nonlinear partial differential equations containing both dispersive and dissipative linear terms. While these investigations may seem unrelated at first glance, some reflection shows that they are in fact closely linked. The investigation of rotating convection makes use of single-space, multiple-time-scale asymptotics to deal with dynamics strongly constrained by rotation. Although the context of thermal convection in an infinite layer seems somewhat removed from large-scale ocean dynamics, the asymptotic

  14. A Numerical Comparison of Three Procedures Used in Failure Model Discrimination

    Directory of Open Access Journals (Sweden)

    Samir Kamel Ashour

    2014-05-01

    Full Text Available Three different selection procedures namely RML, S and F-procedure are reviewed with application to exponential, Weibull, Pareto, and Finite range models. Some inacurate results were discovered in the article of Pandy et al. (1991, it will be illustrated and modified. A simulation study is developed to numerically compare between the three procedures by obtaining the probability of correct selection

  15. Boiling heat transfer on fins – experimental and numerical procedure

    Directory of Open Access Journals (Sweden)

    Orzechowski T.

    2014-03-01

    Full Text Available The paper presents the research methodology, the test facility and the results of investigations into non-isothermal surfaces in water boiling at atmospheric pressure, together with a discussion of errors. The investigations were conducted for two aluminium samples with technically smooth surfaces and thickness of 4 mm and 10 mm, respectively. For the sample of lower thickness, on the basis of the surface temperature distribution measured with an infrared camera, the local heat flux and the heat transfer coefficient were determined and shown in the form of a boiling curve. For the thicker sample, for which 1-D model cannot be used, numerical calculations were conducted. They resulted in obtaining the values of the local heat flux on the surface the invisible to the infrared, camera i.e. on the side on which the boiling of the medium proceeds.

  16. A RANS/DES Numerical Procedure for Axisymmetric Flows with and without Strong Rotation

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Andrew Jacob [Univ. of California, Davis, CA (United States)

    2007-01-01

    A RANS/DES numerical procedure with an extended Lax-Wendroff control-volume scheme and turbulence model is described for the accurate simulation of internal/external axisymmetric flow with and without strong rotation. This new procedure is an extension, from Cartesian to cylindrical coordinates, of (1) a second order accurate multi-grid, control-volume integration scheme, and (2) a k-ω turbulence model. This paper outlines both the axisymmetric corrections to the mentioned numerical schemes and the developments of techniques pertaining to numerical dissipation, multi-block connectivity, parallelization, etc. Furthermore, analytical and experimental case studies are presented to demonstrate accuracy and computational efficiency. Notes are also made toward numerical stability of highly rotational flows.

  17. Rapid, efficient and eco-friendly procedure for the synthesis of ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 129; Issue 2. Rapid, efficient and eco-friendly procedure for the synthesis of quinoxalines under solvent-free conditions using sulfated polyborate as a recyclable catalyst. KRISHNA S INDALKAR CHETAN K KHATRI GANESH U CHATURBHUJ. Rapid Communication ...

  18. Molecular Procedure for Rapid Detection of Burkholderia mallei and Burkholderia pseudomallei

    OpenAIRE

    Bauernfeind, Adolf; Roller, Carsten; Meyer, Detlef; Jungwirth, Renate; Schneider, Ines

    1998-01-01

    A PCR procedure for the discrimination of Burkholderia mallei and Burkholderia pseudomallei was developed. It is based on the nucleotide difference T 2143 C (T versus C at position 2143) between B. mallei and B. pseudomallei detected in the 23S rDNA sequences. In comparison with conventional methods the procedure allows more rapid identification at reduced risk for infection of laboratory personnel.

  19. Numerical simulation of the rapid intensification of Hurricane Katrina (2005): Sensitivity to boundary layer parameterization schemes

    Science.gov (United States)

    Liu, Jianjun; Zhang, Feimin; Pu, Zhaoxia

    2017-04-01

    Accurate forecasting of the intensity changes of hurricanes is an important yet challenging problem in numerical weather prediction. The rapid intensification of Hurricane Katrina (2005) before its landfall in the southern US is studied with the Advanced Research version of the WRF (Weather Research and Forecasting) model. The sensitivity of numerical simulations to two popular planetary boundary layer (PBL) schemes, the Mellor-Yamada-Janjic (MYJ) and the Yonsei University (YSU) schemes, is investigated. It is found that, compared with the YSU simulation, the simulation with the MYJ scheme produces better track and intensity evolution, better vortex structure, and more accurate landfall time and location. Large discrepancies (e.g., over 10 hPa in simulated minimum sea level pressure) are found between the two simulations during the rapid intensification period. Further diagnosis indicates that stronger surface fluxes and vertical mixing in the PBL from the simulation with the MYJ scheme lead to enhanced air-sea interaction, which helps generate more realistic simulations of the rapid intensification process. Overall, the results from this study suggest that improved representation of surface fluxes and vertical mixing in the PBL is essential for accurate prediction of hurricane intensity changes.

  20. Development of a unified numerical procedure for free vibration analysis of structures

    Science.gov (United States)

    Gupta, K. K.

    1981-01-01

    This paper presents the details of a unified numerical algorithm and the associated computer program developed for the efficient determination of natural frequencies and modes of free vibration of structures. Both spinning and nonspinning structures with or without viscous and/or structural damping may be solved by the current procedure; in addition, the program is capable of solving static problems with multiple load cases as well as the quadratic matrix eigenproblem associated with a finite dynamic element structural discretization.

  1. Numerical Modelling of Micro-Stresses in Carbonised Austenitic Cast Steel under Rapid Cooling Conditions

    Directory of Open Access Journals (Sweden)

    Tuleja J.

    2017-06-01

    Full Text Available The paper presents a method of the numerical modelling of micro-stresses in carbonised austenitic cast steel being developed during rapid cooling due to differences in the values of thermal expansion coefficients for this material phases – carbides and austenitic matrix. Micro-stresses are indicated as the main cause of crack initiation in the tooling elements of carburising furnaces being mainly made of austenitic cast steel. A calculation model of carbonised and thermally fatigued austenitic cast steel was developed based on the microstructure images obtained using light microscopy techniques and the phase composition evaluated with the X-ray diffraction method. The values of the stress tensor components and the reduced stress in the complex models of test material structure were determined numerically by the finite element method. The effort analysis was performed and the areas where development of cracks is to be expected were identified, which was experimentally confirmed.

  2. A rapid procedure for routine double staining of cartilage and bone in fetal and adult animals.

    Science.gov (United States)

    Kimmel, C A; Trammell, C

    1981-09-01

    A simple, rapid procedure for dual staining of cartilage and bone in rodents, particularly in late gestation, has been developed for routine use. The procedure involves rapid, complete skinning of fresh eviscerated specimens following a 30 sec immersion in a 70 C water bath. The unfixed specimen is stained in a mixture of 0.14% Alcian blue and 0.12% alizarin red S in ethanol and glacial acetic acid. Specimens are then macerated in 2% KOH, cleared and hardened in 1:1 glycerin and distilled water, and stored in pure glycerin. Rapid staining of cartilage only is done in a mixture of 0.08% Alcian blue, glacial acetic acid, and ethanol, with subsequent maceration, clearing, and hardening as in the double staining procedure. Rapid staining of bone only, concurrent with maceration of soft tissue, can be done by placing fresh, unskinned specimens in a diluted mixture of alizarin red S in 2% KOH, with subsequent clearing and hardening in 1:1 distilled water and glycerin. Good quality fetal specimens can be prepared for examination by any of these procedures in a minimum of 11/2-2 days as compared to a minimum of 4-5 days for other procedures. Double stained specimens can be examined for abnormalities of the cartilage as well as bone.

  3. Molecular Procedure for Rapid Detection of Burkholderia mallei and Burkholderia pseudomallei

    Science.gov (United States)

    Bauernfeind, Adolf; Roller, Carsten; Meyer, Detlef; Jungwirth, Renate; Schneider, Ines

    1998-01-01

    A PCR procedure for the discrimination of Burkholderia mallei and Burkholderia pseudomallei was developed. It is based on the nucleotide difference T 2143 C (T versus C at position 2143) between B. mallei and B. pseudomallei detected in the 23S rDNA sequences. In comparison with conventional methods the procedure allows more rapid identification at reduced risk for infection of laboratory personnel. PMID:9705426

  4. Rapid procedure to calibrate EC-10 and EC-20 capacitance sensors ...

    African Journals Online (AJOL)

    A rapid calibration procedure for EC-10 and EC-20 sensors is introduced to promote the commercial use of these sensors for hydroponic irrigation management in coir. The method is comprised of taking one sensor reading, by a sensor installed under hydroponic crop production conditions, and one gravimetric sample, ...

  5. Rapid procedure to calibrate EC-10 and EC-20 capacitance sensors ...

    African Journals Online (AJOL)

    2013-10-04

    Oct 4, 2013 ... A rapid calibration procedure for EC-10 and EC-20 sensors is introduced to promote the commercial use of these sensors for hydroponic irrigation management in coir. The method is comprised of taking one sensor reading, by a sensor installed under hydroponic crop production conditions, and one ...

  6. Rapid convergence of optimal control in NMR using numerically-constructed toggling frames

    Science.gov (United States)

    Coote, Paul; Anklin, Clemens; Massefski, Walter; Wagner, Gerhard; Arthanari, Haribabu

    2017-08-01

    We present a numerical method for rapidly solving the Bloch equation for an arbitrary time-varying spin-1/2 Hamiltonian. The method relies on fast, vectorized computations such as summation and quaternion multiplication, rather than slow computations such as matrix exponentiation. A toggling frame is constructed in which the Hamiltonian is time-invariant, and therefore has a simple analytical solution. The key insight is that constructing this frame is faster than solving the system dynamics in the original frame. Rapidly solving the Bloch equations for an arbitrary Hamiltonian is particularly useful in the context of NMR optimal control. Optimal control theory can be used to design pulse shapes for a range of tasks in NMR spectroscopy. However, it requires multiple simulations of the Bloch equations at each stage of the algorithm, and for each relevant set of parameters (e.g. chemical shift frequencies). This is typically time consuming. We demonstrate that by working in an appropriate toggling frame, optimal control pulses can be generated much faster. We present a new alternative to the well-known GRAPE algorithm to continuously update the toggling-frame as the optimal pulse is generated, and demonstrate that this approach is extremely fast. The use and benefit of rapid optimal pulse generation is demonstrated for 19F fragment screening experiments.

  7. Using Shack-Hartmann wavefront sensors and Zernike coefficients for beam characterisation: numerical procedures

    Science.gov (United States)

    Bosch, Salvador; Vallmitjana, Santiago; Marzoa, Antonio; Arines, Justo; Acosta, Eva

    2017-06-01

    When using Shack-Hartmann wavefront sensors (SH) and Zernike coefficients (Zs) in applications where the position of the measurement and the point of interest are far apart, as it is common practice in ophthalmic optics, problems in the interpretation of the values of the Zs arise, related to how the shape of the wavefront propagates along the beam. One typical example is pupil conjugation where an auxiliary lens is added to match the size of the area of the interest of the beam with the size of the entrance pupil of the SH used for measurements. In the present work, we address this problem in the framework of a numerical scheme for modeling the beam propagation. We calculate the wavefronts with exact ray tracing plus the fitting of the impacts so as to match a rectangular grid. This procedure allows the subsequent calculation of the Zs or, similarly, the pupil function at an arbitrary plane perpendicular to the optical axis. All the numerical methods and procedures have been implemented in MATLAB code and can be illustrated by running the MATLAB script for the setup configuration that is being considered. Several examples are presented to illustrate the previous ideas and to show the real capabilities of our procedures. They will help to clarify the issues actually found in practical setups for beam manipulation, often encountered in ophthalmic optics.

  8. Numerical simulations of thermal convection in rapidly rotating spherical fluid shells

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Z.P.

    1992-01-01

    Numerical simulations of thermal convection in rapidly rotating spherical shells of Boussinesq fluid have been carried out with a nonlinear, three-dimensional, time-dependent spectral-transform code. The basic state is hydrostatic, spherically symmetric, and independent of time. The numerical methods, the numerical stability, and the adequacy of the spatial resolution were examined by a benchmarking study. A sequence of bifurcations from the onset of a steadily propagating convective state, to a periodic state, to a quasi-periodic state and thence a chaotic state has been found. Convective solutions at each stage along the route to chaos have been studied. The emphases are on the three-dimensional and time-dependent convective structures and associated mean zonal flow. The spherical shell is heated from both below and within. The boundaries are isothermal and stress-free. The author has also explored the consequences of imposing a spatially varying temperature anomaly on the upper surface of a spherical shell on thermal convection in the shell. The spherical shell is heated from below and cooled from above. The lower boundary is isothermal and both boundaries are rigid and impermeable. The results show that the patterns and amplitudes of the convective motions and associated mean zonal and meridional flows depend largely on the pattern and amplitude of the imposted thermal anomaly. The purpose of this study is to illustrate the influence of thermal conditions in the lower mantle on motions in the Earth's liquid outer core. The author has carried out numerical simulations at both high Taylor and Rayleigh numbers. The spherical shell is heated from below and cooled from above. The boundaries are isothermal and stress-free. Columnar rolls that are quasi-layered in cylindrical radius and associated banded mean zonal flow are obtained. The quasi-layered convective structure and the banded zonal wind are consequent upon both the high Taylor and Rayleigh numbers.

  9. Laboratory-numerical models of rapidly rotating convection in planetary cores

    Science.gov (United States)

    Cheng, J. S.; Stellmach, S.; Ribeiro, A.; Grannan, A.; King, E. M.; Aurnou, J. M.

    2015-04-01

    We present laboratory and numerical models investigating the behavioural regimes of rapidly rotating convection in high-latitude planetary core-style settings. Our combined laboratory-numerical approach, utilizing simplified geometries, can access more extreme parameters (e.g. Rayleigh numbers Ra ≲ 1013; Nusselt numbers Nu ≲ 103; Ekman numbers E ≳ 3 × 10- 8) than current global-scale dynamo simulations. Using flow visualizations and heat transfer measurements, we study the axialized flows that exist near the onset of rotating convection, as well as the 3-D flows that develop with stronger forcing. With water as the working fluid (Prandtl number Pr ≃ 7), we find a steep scaling trend for rapidly rotating convective heat transfer, Nu ˜ (Ra/RaC)3.6, that is associated with the existence of coherent, axialized columns. This rapidly rotating trend is steeper than the trends found at moderate values of the Ekman number, and continues a trend of ever-steepening scalings as the rotation rate of the system is increased. In contrast, in more strongly forced or lower rotation rate cases, the heat transfer scaling consistently follows a shallower slope equivalent to that of non-rotating convection systems. The steep heat transfer scaling in the columnar convection regime, corroborated by our laboratory flow visualizations, imply that coherent, axial columns have a relatively narrow range of stability. Thus, we hypothesize that coherent convection columns are not stable in planetary core settings, where the Ekman number is estimated to be ˜10-15. As a consequence, convective motions in the core may not be related to the columnar motions found in present-day global-scale models. Instead, we hypothesize that turbulent rotating convection cascades energy upwards from 3-D motions to large-scale quasi-2-D flow structures that are capable of efficiently generating planetary-scale magnetic fields. We argue that the turbulent regimes of rapidly rotating convection are

  10. Numerical Investigation of the Transient Behavior of a Hot Gas Duct under Rapid Depressurization

    Directory of Open Access Journals (Sweden)

    JingBao Liu

    2016-01-01

    Full Text Available A hot gas duct is an indispensable component for the nuclear-process heat applications of the Very-High-Temperature Reactor (VHTR, which has to fulfill three requirements: to withstand high temperature, high pressure, and large pressure transient. In this paper, numerical investigation of pressure transient is performed for a hot gas duct under rapid depressurization. System depressurization imposes an imploding pressure differential on the internal structural elements of a hot gas duct, the structural integrity of which is susceptible to being damaged. Pressure differential and its imposed duration, which are two key factors to evaluate the damage severity of a hot gas duct under depressurization, are examined in regard to depressurization rate and insulation packing tightness. It is revealed that depressurization rate is a decisive parameter for controlling the pressure differential and its duration, whereas insulating-packing tightness has little effect on them.

  11. Decreasing pressure ulcer risk during hospital procedures: a rapid process improvement workshop.

    Science.gov (United States)

    Haugen, Vicki; Pechacek, Judy; Maher, Travis; Wilde, Joy; Kula, Larry; Powell, Julie

    2011-01-01

    A 300-bed acute care community hospital used a 2-day "Rapid Process Improvement Workshop" to identify factors contributing to facility-acquired pressure ulcers (PU). The Rapid Process Improvement Workshop included key stakeholders from all procedural areas providing inpatient services and used standard components of rapid process improvement: data analysis, process flow charting, factor identification, and action plan development.On day 1, the discovery process revealed increased PU risk related to prolonged immobility when transporting patients for procedures, during imaging studies, and during the perioperative period. On day 2, action plans were developed that included communication of PU risk or presence of an ulcer,measures to shorten procedure times when clinically appropriate, implementation of prevention techniques during procedures, and recommendations for mattress upgrades. In addition, educational programs about PU prevention were developed, schedules for presentations were established, and an online power point presentation was completed and placed in a learning management system module. Finally, our nursing department amended a hospital wide handoff communication tool to include skin status and PU risk level. This tool is used in all patient handoff situations, including nonnursing departments such as radiology. Patients deemed at risk for ulcers were provided "Braden Risk" armbands to enhance interdepartmental awareness.

  12. Numerical Modelling of Rayleigh Wave Propagation in Course of Rapid Impulse Compaction

    Science.gov (United States)

    Herbut, Aneta; Rybak, Jarosław

    2017-10-01

    As the soil improvement technologies are the area of a rapid development, they require designing and implementing novel methods of control and calibration in order to ensure the safety of geotechnical works. At Wroclaw University of Science and Technology (Poland), these new methods are continually developed with the aim to provide the appropriate tools for the preliminary design of work process, as well as for the further ongoing on-site control of geotechnical works (steel sheet piling, pile driving or soil improvement technologies). The studies include preliminary numerical simulations and field tests concerning measurements and continuous histogram recording of shocks and vibrations and its ground-born dynamic impact on engineering structures. The impact of vibrations on reinforced concrete and masonry structures in the close proximity of the construction site may be destroying in both architectural and structural meaning. Those limits are juxtaposed in codes of practice, but always need an individual judgment. The results and observations make it possible to delineate specific modifications to the parameters of technology applied (e.g. hammer drop height). On the basis of numerous case studies of practical applications, already summarized and published, we were able to formulate the guidelines for work on the aforementioned sites. This work presents specific aspects of the active design (calibration of building site numerical model) by means of technology calibration, using the investigation of the impact of vibrations that occur during the Impulse Compaction on adjacent structures. A case study entails the impact of construction works on Rayleigh wave propagation in the zone of 100 m (radius) around the Compactor.

  13. Numerical sensitivity analysis of a variational data assimilation procedure for cardiac conductivities

    Science.gov (United States)

    Barone, Alessandro; Fenton, Flavio; Veneziani, Alessandro

    2017-09-01

    An accurate estimation of cardiac conductivities is critical in computational electro-cardiology, yet experimental results in the literature significantly disagree on the values and ratios between longitudinal and tangential coefficients. These are known to have a strong impact on the propagation of potential particularly during defibrillation shocks. Data assimilation is a procedure for merging experimental data and numerical simulations in a rigorous way. In particular, variational data assimilation relies on the least-square minimization of the misfit between simulations and experiments, constrained by the underlying mathematical model, which in this study is represented by the classical Bidomain system, or its common simplification given by the Monodomain problem. Operating on the conductivity tensors as control variables of the minimization, we obtain a parameter estimation procedure. As the theory of this approach currently provides only an existence proof and it is not informative for practical experiments, we present here an extensive numerical simulation campaign to assess practical critical issues such as the size and the location of the measurement sites needed for in silico test cases of potential experimental and realistic settings. This will be finalized with a real validation of the variational data assimilation procedure. Results indicate the presence of lower and upper bounds for the number of sites which guarantee an accurate and minimally redundant parameter estimation, the location of sites being generally non critical for properly designed experiments. An effective combination of parameter estimation based on the Monodomain and Bidomain models is tested for the sake of computational efficiency. Parameter estimation based on the Monodomain equation potentially leads to the accurate computation of the transmembrane potential in real settings.

  14. Innovative and rapid procedure for 4-hydroxyproline determination in meat-based foods.

    Science.gov (United States)

    Messia, Maria Cristina; Marconi, Emanuele

    2012-01-01

    This report describes a rapid and innovative microwave procedure for protein hydrolysis coupled with high performance anion exchange chromatography and pulsed amperometric detection (HPAEC-PAD) to quantify the amino acid 4-hydroxyproline in meat and meat-based products. This innovative approach was successfully applied to determine collagen content (4-hydroxyproline × 8) as the index quality of meat material used in the preparation of typical meat-based foods.

  15. [Rapid identification of microorganisms by mass spectrometry in a blood culture system. Comparison of two procedures].

    Science.gov (United States)

    Cattani, María E; Posse, Tamara; Hermes, Ricardo L; Kaufman, Sara C

    2015-01-01

    Rapid identification of microorganisms is critical in hospitalized infected patients. Blood culture is currently the gold standard for detecting and identifying microorganisms causing bacteremia or sepsis. The introduction of mass spectrometry by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF MS) in microbiology laboratories, especially in microorganisms growing in blood culture bottles, provides rapid identification. This study evaluates the performance of the Maldi Sepsityper Biotyper procedure (hereinafter, MS) compared to that of an in-home method (hereinafter, HF). Eight hundred and forty (840) positive blood culture bottles were processed using the HF procedure, 542 of which were also processed using MS. The organisms were identified in 670 (79.76%) and 391 (72.14%) bottles respectively (p = 0,0013). This study demonstrates the effectiveness of both procedures for identifying microorganisms directly from positive blood culture bottles. However, the HF procedure proved to be more effective than MS, especially in the presence of Gram positive organisms. Copyright © 2015 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.

  16. Numerical study on dynamic characteristics for sharp opening procedure of boundary-layer suction slot

    Science.gov (United States)

    He, Yubao; Yin, Hang; Huang, Hongyan; Yu, Daren

    2017-08-01

    Based on the sharp forward of shock train and taking the forthcoming unstart for a background, the dynamic characteristics for sharp opening procedure of boundary-layer suction slot are investigated numerically using the dynamic mesh technique. Results indicate that the climbing path of shock train with the complex background waves exhibits a sharp and slow forward state at different time. The compression waves in the primary shock sweep the trailing edge of the separation bubble, and the recirculation within the shock train is communicated with the separation bubble, which reveals that the flow is in a critical state and is about to be unstart at the subsequent time. Furthermore, the dynamic pattern for sharp opening procedure of boundary-layer suction slot can be classified into four distinct stages, namely, the formation of the jet plume without suction mass loss, the formation of the barrier shock with suction mass loss characterized by gradient increase and subsequent two oscillations, the evolution of the barrier shock and jet plume with suction mass loss that ramps up via a series of discrete step increases, and the formation of the stable structure accompanied by the linear suction mass loss.

  17. Benchmarking an operational procedure for rapid flood mapping and risk assessment in Europe

    Science.gov (United States)

    Dottori, Francesco; Salamon, Peter; Kalas, Milan; Bianchi, Alessandra; Feyen, Luc

    2016-04-01

    The development of real-time methods for rapid flood mapping and risk assessment is crucial to improve emergency response and mitigate flood impacts. This work describes the benchmarking of an operational procedure for rapid flood risk assessment based on the flood predictions issued by the European Flood Awareness System (EFAS). The daily forecasts produced for the major European river networks are translated into event-based flood hazard maps using a large map catalogue derived from high-resolution hydrodynamic simulations, based on the hydro-meteorological dataset of EFAS. Flood hazard maps are then combined with exposure and vulnerability information, and the impacts of the forecasted flood events are evaluated in near real-time in terms of flood prone areas, potential economic damage, affected population, infrastructures and cities. An extensive testing of the operational procedure is carried out using the catastrophic floods of May 2014 in Bosnia-Herzegovina, Croatia and Serbia. The reliability of the flood mapping methodology is tested against satellite-derived flood footprints, while ground-based estimations of economic damage and affected population is compared against modelled estimates. We evaluated the skill of flood hazard and risk estimations derived from EFAS flood forecasts with different lead times and combinations. The assessment includes a comparison of several alternative approaches to produce and present the information content, in order to meet the requests of EFAS users. The tests provided good results and showed the potential of the developed real-time operational procedure in helping emergency response and management.

  18. Numerical simulation of draining and drying procedure for the ITER Generic Equatorial Port Plug cooling system

    Energy Technology Data Exchange (ETDEWEB)

    Tanchuk, Victor, E-mail: Victor.Tanchuk@sintez.niiefa.spb.su [JSC “D.V. Efremov Institute of Electrophysical Apparatus”, 196641 St. Petersburg (Russian Federation); Grigoriev, Sergey; Lyublin, Boris [JSC “D.V. Efremov Institute of Electrophysical Apparatus”, 196641 St. Petersburg (Russian Federation); Maquet, Philippe [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); Senik, Konstantin [JSC “D.V. Efremov Institute of Electrophysical Apparatus”, 196641 St. Petersburg (Russian Federation); Pak, Sunil [National Fusion Research Institute, Daejeon (Korea, Republic of); Udintsev, Victor [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France)

    2016-11-01

    Highlights: • The cooling system of the ITER Generic Equatorial Port Plug (GEPP) is of a complicated combination of horizontal and vertical channels. • The calculation model for the entire GEPP cooling circuit comprising 12 sub-circuits and built up of 2421 finite-volume elements has been developed. • Transient analysis of this model simulating the draining procedure by the KORSAR/B1 code has been performed. • Water in amount of 263 g of initial 531 kg in the GEPP remains in the dead-ends of the DSM and DFW channels in 150 s of draining procedure. • Almost 3 h are required to boil off 263 g of water trapped in the dead-ends. - Abstract: For effective vacuum leak testing all cooling circuits serving the ITER vessel and in-vessel components shall be drained and dried so that after this procedure taking less than 100 h the purge gas passing through a component has water content less than 100 ppm. This process is four-stage, with the first stage using a short blast of compressed nitrogen to blow most of water in the coolant channels out of the circuit. This process is hindered by volumes which trap water due to gravity. To remove the trapped water, it is necessary, first, to heat up the structure by hot and compressed nitrogen, and then water is evaporated by depressurized nitrogen. The cooling system of the ITER Diagnostic Equatorial Port Plugs is of a complicated hydraulic configuration. The system branching might make difficult removal of water from the piping in the scheduled draining mode. The authors have proposed the KORSAR computation code to simulate draining of the GEPP cooling circuit. The numerical simulation performed has made it possible to describe the process dynamics during draining of the entire GEPP cooling circuit and to define the process time, amount and location of residual water and evolution of two-phase flow regime.

  19. New and rapid procedure for the isolation of ultra-high molecular weight eukaryotic DNA

    Energy Technology Data Exchange (ETDEWEB)

    Longmire, J.L.; Lewis, A.; Meincke, L.J.; Hildebrand, C.E.

    1986-05-01

    The authors have developed a novel procedure that permits the rapid extraction and isolation of ultra-high molecular weight DNA from avian or mammalian cells using dialysis against a solution of polyethylene glycol (PEG). Cells harvested by centrifugation and washed twice in ice-cold Ca/sup + +/- and Mg/sup + +/-free phosphate buffered saline were resuspended in 5 ml 0.01 M Tris-Cl (pH 8.0); 0.001 M EDTA (TE); sodium dodecyl sulfate and proteinase K were added to final concentrations of 0.1% and 0.1 mg/ml, respectively. After incubation at 37/sup 0/C overnight, the viscous solution was transferred to a mini-collodian bag and concentrated by dialysis against 4-5 changes of 20% PEG in TE over a period of 5 hours at RT. Concentrated samples were desalted by dialysis against fresh TE for two 15 minute intervals. DNA obtained using this procedure gives A/sub 260//A/sub 280/ consistently >1.8. Analysis of DNA size using pulsed field gel electrophoresis revealed a distribution of fragments >500 Kb in length. Further measurements examined were (1) restriction enzyme digestibility, (2) ligation efficiency of restricted DNA, and (3) cloning efficiency using the lambda vector Ch21A. This novel methodology offers a valuable alternative protocol for rapid purification of ultrahigh molecular weight DNA for various applications in molecular biology.

  20. Experimental and numerical simulation of the acquisition of chemical remanent magnetization and the Thellier procedure

    Science.gov (United States)

    Shcherbakov, V. P.; Sycheva, N. K.; Gribov, S. K.

    2017-09-01

    The results of the Thellier-Coe experiments on paleointensity determination on the samples which contain chemical remanent magnetization (CRM) created by thermal annealing of titanomagnetites are reported. The results of the experiments are compared with the theoretical notions. For this purpose, Monte Carlo simulation of the process of CRM acquisition in the system of single-domain interacting particles was carried out; the paleointensity determination method based on the Thellier-Coe procedure was modeled; and the degree of paleointensity underestimation was quantitatively estimated based on the experimental data and on the numerical results. Both the experimental investigations and computer modeling suggest the following main conclusion: all the Arai-Nagata diagrams for CRM in the high-temperature area (in some cases up to the Curie temperature T c) contain a relatively long quasi-linear interval on which it is possible to estimate the slope coefficient k and, therefore, the paleointensity. Hence, if chemical magnetization (or remagnetization) took place in the course of the magnetomineralogical transformations of titanomagnetite- bearing igneous rocks during long-lasting cooling or during repeated heatings, it can lead to incorrect results in determining the intensity of the geomagnetic field in the geological past.

  1. SU-E-T-432: A Rapid and Comprehensive Procedure for Daily Proton QA

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, T; Sun, B; Grantham, K; Knutson, N; Santanam, L; Goddu, S; Klein, E [Washington University, St. Louis, MO (United States)

    2014-06-01

    Purpose: The objective is to develop a rapid and comprehensive daily QA procedure implemented at the S. Lee Kling Proton Therapy Center at Barnes-Jewish Hospital. Methods: A scribed phantom with imbedded fiducials is used for checking lasers accuracy followed by couch isocentricity and for X-ray imaging congruence with isocenter. A Daily QA3 device (Sun Nuclear, FL) was used to check output, range and profiles. Five chambers in the central region possess various build-ups. After converting the thickness of the inherent build-ups into water equivalent thickness (WET) for proton, range of any beam can be checked with additional build-up on the Daily QA3 device. In our procedure, 3 beams from 3 bands (large, small and deep) with nominal range of 20 cm are checked daily. 17cm plastic water with WET of 16.92cm are used as additional build-up so that four chambers sit on the SOBP plateau at various depths and one sit on the distal fall off. Reading from the five chambers are fitted to an error function that has been parameterized to match the SOBP with the same nominal range. Shifting of the error function to maximize the correlation between measurements and the error function is deemed as the range shift from the nominal value. Results: We have found couch isocentricity maintained over 180 degrees. Imaging system exhibits accuracy in regard to imaging and mechanical isocenters. Ranges are within 1mm accuracy from measurements in water tank, and sensitive to change of sub-millimeter. Data acquired since the start of operation show outputs, profiles and range stay within 1% or 1mm from baselines. The whole procedure takes about 40 minutes. Conclusion: Taking advantage of the design of Daily QA3 device turns the device originally designed for photon and electron into a comprehensive and rapid tool for proton daily QA.

  2. Measurement of humic and fulvic acid concentrations and dissolution properties by a rapid batch procedure

    Energy Technology Data Exchange (ETDEWEB)

    Van Zomeren, A.; Comans, R.N.J. [ECN Biomass, Coal and Environmental Research, Petten (Netherlands)

    2007-08-29

    Although humic substances (HS) strongly facilitate the transport of metals and hydrophobic organic contaminants in environmental systems, their measurement is hampered by the time-consuming nature of currently available methods for their isolation and purification. We present and apply a new rapid batch method to measure humic (HA) and fulvic (FA) acid concentrations and dissolution properties in both solid and aqueous samples. The method is compared with the conventional procedures and is shown to substantially facilitate HS concentration measurements, particularly for applications such as geochemical modeling where HS purification is not required. The new method can be performed within 1.5-4 h per sample and multiple samples can be processed simultaneously, while the conventional procedures typically require approximately 40 h for a single sample. In addition, specific dissolution properties of HS are identified and are consistent with recent views on the molecular structure of HS that emphasize molecular interactions of smaller entities over distinct macromolecular components. Because the principles of the new method are essentially the same as those of generally accepted conventional procedures, the identified HA and FA properties are of general importance for the interpretation of the environmental occurrence and behavior of HS.

  3. Numerical

    Directory of Open Access Journals (Sweden)

    M. Boumaza

    2015-07-01

    Full Text Available Transient convection heat transfer is of fundamental interest in many industrial and environmental situations, as well as in electronic devices and security of energy systems. Transient fluid flow problems are among the more difficult to analyze and yet are very often encountered in modern day technology. The main objective of this research project is to carry out a theoretical and numerical analysis of transient convective heat transfer in vertical flows, when the thermal field is due to different kinds of variation, in time and space of some boundary conditions, such as wall temperature or wall heat flux. This is achieved by the development of a mathematical model and its resolution by suitable numerical methods, as well as performing various sensitivity analyses. These objectives are achieved through a theoretical investigation of the effects of wall and fluid axial conduction, physical properties and heat capacity of the pipe wall on the transient downward mixed convection in a circular duct experiencing a sudden change in the applied heat flux on the outside surface of a central zone.

  4. A testing procedure for triaxial tests and a numerical method for the calculation of powder flow properties

    NARCIS (Netherlands)

    Eelkman Rooda, J.; Haaker, G.

    1977-01-01

    A testing procedure for measuring flow properties of powders is developed which makes it possible to use results from triaxial tests in the Jenike bin theory. For the elaboration of the results a numerical method is used, based upon the Warren Spring equation (τ/C)N = (σ + T)/T. In this equation σ

  5. Numerical modeling of rapidly varying flows using HEC-RAS and WSPG models.

    Science.gov (United States)

    Rao, Prasada; Hromadka, Theodore V

    2016-01-01

    The performance of two popular hydraulic models (HEC-RAS and WSPG) for modeling hydraulic jump in an open channel is investigated. The numerical solutions are compared with a new experimental data set obtained for varying channel bottom slopes and flow rates. Both the models satisfactorily predict the flow depths and location of the jump. The end results indicate that the numerical models output is sensitive to the value of chosen roughness coefficient. For this application, WSPG model is easier to implement with few input variables.

  6. Advanced Numerical Imaging Procedure Accounting for Non-Ideal Effects in GPR Scenarios

    Science.gov (United States)

    Comite, Davide; Galli, Alessandro; Catapano, Ilaria; Soldovieri, Francesco

    2015-04-01

    advanced implementation have also been tested by introducing 'errors' on the knowledge of the background medium permittivity, by simulating the presence of one or more layers, and by choosing different models of the surface roughness. The impact of these issues on the performance of both the conventional procedure and the advanced one will be extensively highlighted and discussed at the conference. [1] G. Valerio et al., "GPR detectability of rocks in a Martian-like shallow subsoil: A numerical approach," Plan. Sp. Sci., vol. 62, pp. 31-40, 2012. [2] A. Galli et al., "3D imaging of buried dielectric targets with a tomographic microwave approach applied to GPR synthetic data," Int. J. Antennas Propag., art. ID 610389, 10 pp., 2013 [3] F. Soldovieri et al., "A linear inverse scattering algorithm for realistic GPR applications," Near Surface Geophysics, 5 (1), pp. 29-42, 2007.

  7. Rapid expansion of intravitreal drug injection procedures, 2000 to 2008: a population-based analysis.

    Science.gov (United States)

    Campbell, Robert J; Bronskill, Susan E; Bell, Chaim M; Paterson, J Michael; Whitehead, Marlo; Gill, Sudeep S

    2010-03-01

    To evaluate patterns of care for age-related macular degeneration following the introduction of vascular endothelial growth factor inhibitors. Using a population-based retrospective design, we studied monthly fee claims for intravitreal injections submitted to the Ontario Health Insurance Plan between January 1, 2000, and March 30, 2008, and linked procedures to the physicians who performed them. This database records physician services provided as part of universal health care insurance coverage in Ontario, Canada. This program covers all residents of Ontario, which had an average population of 12.1 million during the study period. Following regulatory approval of bevacizumab for colorectal cancer in 2005, off-label use of this drug for the treatment of retinal disease, particularly age-related macular degeneration, became increasingly common. The rate of intravitreal injections in Ontario rapidly grew 8-fold, and this growth preceded the availability of ranibizumab by more than a year. Moreover, in 2007, more than 50% of intravitreal injections in Ontario were performed by 3% of ophthalmologists. The development of vascular endothelial growth factor inhibitors has revolutionized the treatment of age-related macular degeneration. To our knowledge, this study is the first to quantify the dramatic uptake of these treatments at a population level. Our findings also suggest that off-label injection of bevacizumab was highly prevalent in Ontario. Serial intravitreal injections requiring direct physician administration and the concentration of injection procedures in the hands of a small number of ophthalmologists have the potential to affect services for other vision-threatening conditions.

  8. Rapid assessment procedures in environmental sanitation research: a case study from the northern border of Mexico.

    Science.gov (United States)

    Cifuentes, Enrique; Alamo, Urinda; Kendall, Tamil; Brunkard, Joan; Scrimshaw, Susan

    2006-01-01

    There is a need to enhance the quality and sustainability of environmental health programs in Mexico. What socio-cultural factors influenced the adoption or rejection of Clean Water in Homes programs in this population? We applied rapid appraisal procedures (RAP) to evaluate these community-based programs. Qualitative study conducted in communities along Mexico's northern border. We conducted informal dialogues, semi-structured interviews, field notes and observations. Home visits used a checklist to observe: sources of water, handwashing, as well as human waste and garbage disposal patterns. Data analysis was conducted using ATLAS.ti, which facilitated comparison and illustration of discrepancies, the elaboration of emerging issues and relationships between them. Community members perceived that the Clean Water program was a top-down intervention. Water is perceived as a political issue and a matter of corruption. Inequity also limits solidarity activities involved in environmental sanitation. Migration to the United States of America (US) contributes to community fragmentation, which in turn dilutes communal efforts to improve water and sanitation infrastructure. While targeting women as program "recipients", the Clean Water program did not take gendered spheres of decision-making into account. Community members and authorities discussed the main results in "assemblies", particularly addressing the needs of excluded groups. The oversight of not exploring community members' needs and priorities prior to program implementation resulted in interventions that did not address the structural (economic, infrastructure) and socio-cultural barriers faced by community members to undertake the health-promoting behaviour change, and provoked resentment.

  9. Rapid forecasting of tsunami runup heights from 2-D numerical simulations

    Directory of Open Access Journals (Sweden)

    B. H. Choi

    2011-03-01

    Full Text Available We propose a method to compute tsunami runup heights that is based on an integration of numerical, 2-D shallow-water modelling and an analytical, 1-D long-wave runup theory. This approach provides a faster forecast of tsunami runup heights than a complicated coastal inundation model. Through simulations of potential tsunami scenarios, this approach can also be applied to long-term tsunami prediction. We tested the model by simulating the historical event in the East (Japan Sea and found that the estimates of runup heights agreed well with the available observations.

  10. Numerical simulation of a plane turbulent mixing layer, with applications to isothermal, rapid reactions

    Science.gov (United States)

    Lin, P.; Pratt, D. T.

    1987-01-01

    A hybrid method has been developed for the numerical prediction of turbulent mixing in a spatially-developing, free shear layer. Most significantly, the computation incorporates the effects of large-scale structures, Schmidt number and Reynolds number on mixing, which have been overlooked in the past. In flow field prediction, large-eddy simulation was conducted by a modified 2-D vortex method with subgrid-scale modeling. The predicted mean velocities, shear layer growth rates, Reynolds stresses, and the RMS of longitudinal velocity fluctuations were found to be in good agreement with experiments, although the lateral velocity fluctuations were overpredicted. In scalar transport, the Monte Carlo method was extended to the simulation of the time-dependent pdf transport equation. For the first time, the mixing frequency in Curl's coalescence/dispersion model was estimated by using Broadwell and Breidenthal's theory of micromixing, which involves Schmidt number, Reynolds number and the local vorticity. Numerical tests were performed for a gaseous case and an aqueous case. Evidence that pure freestream fluids are entrained into the layer by large-scale motions was found in the predicted pdf. Mean concentration profiles were found to be insensitive to Schmidt number, while the unmixedness was higher for higher Schmidt number. Applications were made to mixing layers with isothermal, fast reactions. The predicted difference in product thickness of the two cases was in reasonable quantitative agreement with experimental measurements.

  11. Fostering Scientific and Numerate Practices in Journalism to Support Rapid Public Learning

    Directory of Open Access Journals (Sweden)

    Louise Yarnall

    2017-01-01

    Full Text Available Journalism has the potential––and arguably the mandate––to expand public understanding of societally important phenomena. However, some methods for more effectively educating the public have been persistently underutilized: in particular, embedding informative numerical rates and efficient scientific explanations in news reports. In the current era of disrupting and downsizing the news business, the challenges to using such methods have only increased. To address this problem, this article seeks to (a raise awareness about the psychological reasons that help explain why it is crucial to use such elements in news reports, and (b exhibit some methods for doing so that require modest effort. Building on a review of relevant psychological literatures, principles, and existing reporting methods, we describe findings from a series of cognitive-scientific studies that demonstrate how using key––and relatively minimal––scientific and numerical elements can enhance public learning from news reports. We conclude by also describing curricula and resources designed to help journalists and bloggers use these methods.

  12. Rapid and efficient filtration-based procedure for separation and safe analysis of CBRN mixed samples.

    Directory of Open Access Journals (Sweden)

    Mostafa Bentahir

    Full Text Available Separating CBRN mixed samples that contain both chemical and biological warfare agents (CB mixed sample in liquid and solid matrices remains a very challenging issue. Parameters were set up to assess the performance of a simple filtration-based method first optimized on separate C- and B-agents, and then assessed on a model of CB mixed sample. In this model, MS2 bacteriophage, Autographa californica nuclear polyhedrosis baculovirus (AcNPV, Bacillus atrophaeus and Bacillus subtilis spores were used as biological agent simulants whereas ethyl methylphosphonic acid (EMPA and pinacolyl methylphophonic acid (PMPA were used as VX and soman (GD nerve agent surrogates, respectively. Nanoseparation centrifugal devices with various pore size cut-off (30 kD up to 0.45 µm and three RNA extraction methods (Invisorb, EZ1 and Nuclisens were compared. RNA (MS2 and DNA (AcNPV quantification was carried out by means of specific and sensitive quantitative real-time PCRs (qPCR. Liquid chromatography coupled to time-of-flight mass spectrometry (LC/TOFMS methods was used for quantifying EMPA and PMPA. Culture methods and qPCR demonstrated that membranes with a 30 kD cut-off retain more than 99.99% of biological agents (MS2, AcNPV, Bacillus Atrophaeus and Bacillus subtilis spores tested separately. A rapid and reliable separation of CB mixed sample models (MS2/PEG-400 and MS2/EMPA/PMPA contained in simple liquid or complex matrices such as sand and soil was also successfully achieved on a 30 kD filter with more than 99.99% retention of MS2 on the filter membrane, and up to 99% of PEG-400, EMPA and PMPA recovery in the filtrate. The whole separation process turnaround-time (TAT was less than 10 minutes. The filtration method appears to be rapid, versatile and extremely efficient. The separation method developed in this work constitutes therefore a useful model for further evaluating and comparing additional separation alternative procedures for a safe handling and

  13. Rapid and Efficient Filtration-Based Procedure for Separation and Safe Analysis of CBRN Mixed Samples

    Science.gov (United States)

    Bentahir, Mostafa; Laduron, Frederic; Irenge, Leonid; Ambroise, Jérôme; Gala, Jean-Luc

    2014-01-01

    Separating CBRN mixed samples that contain both chemical and biological warfare agents (CB mixed sample) in liquid and solid matrices remains a very challenging issue. Parameters were set up to assess the performance of a simple filtration-based method first optimized on separate C- and B-agents, and then assessed on a model of CB mixed sample. In this model, MS2 bacteriophage, Autographa californica nuclear polyhedrosis baculovirus (AcNPV), Bacillus atrophaeus and Bacillus subtilis spores were used as biological agent simulants whereas ethyl methylphosphonic acid (EMPA) and pinacolyl methylphophonic acid (PMPA) were used as VX and soman (GD) nerve agent surrogates, respectively. Nanoseparation centrifugal devices with various pore size cut-off (30 kD up to 0.45 µm) and three RNA extraction methods (Invisorb, EZ1 and Nuclisens) were compared. RNA (MS2) and DNA (AcNPV) quantification was carried out by means of specific and sensitive quantitative real-time PCRs (qPCR). Liquid chromatography coupled to time-of-flight mass spectrometry (LC/TOFMS) methods was used for quantifying EMPA and PMPA. Culture methods and qPCR demonstrated that membranes with a 30 kD cut-off retain more than 99.99% of biological agents (MS2, AcNPV, Bacillus Atrophaeus and Bacillus subtilis spores) tested separately. A rapid and reliable separation of CB mixed sample models (MS2/PEG-400 and MS2/EMPA/PMPA) contained in simple liquid or complex matrices such as sand and soil was also successfully achieved on a 30 kD filter with more than 99.99% retention of MS2 on the filter membrane, and up to 99% of PEG-400, EMPA and PMPA recovery in the filtrate. The whole separation process turnaround-time (TAT) was less than 10 minutes. The filtration method appears to be rapid, versatile and extremely efficient. The separation method developed in this work constitutes therefore a useful model for further evaluating and comparing additional separation alternative procedures for a safe handling and

  14. Application of a trigonometric finite difference procedure to numerical analysis of compressive and shear buckling of orthotropic panels

    Science.gov (United States)

    Stein, M.; Housner, J. D.

    1978-01-01

    A numerical analysis developed for the buckling of rectangular orthotropic layered panels under combined shear and compression is described. This analysis uses a central finite difference procedure based on trigonometric functions instead of using the conventional finite differences which are based on polynomial functions. Inasmuch as the buckle mode shape is usually trigonometric in nature, the analysis using trigonometric finite differences can be made to exhibit a much faster convergence rate than that using conventional differences. Also, the trigonometric finite difference procedure leads to difference equations having the same form as conventional finite differences; thereby allowing available conventional finite difference formulations to be converted readily to trigonometric form. For two-dimensional problems, the procedure introduces two numerical parameters into the analysis. Engineering approaches for the selection of these parameters are presented and the analysis procedure is demonstrated by application to several isotropic and orthotropic panel buckling problems. Among these problems is the shear buckling of stiffened isotropic and filamentary composite panels in which the stiffener is broken. Results indicate that a break may degrade the effect of the stiffener to the extent that the panel will not carry much more load than if the stiffener were absent.

  15. Numerical analysis of the rapid solidification of gas-atomized Al-8 wt pct Fe droplets

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S.G. (Kunsan National Univ. (Korea, Republic of)); Shin, S.H. (Sammi Steel Corp., Changwon (Korea, Republic of). Central Research Inst.); Suzuki, Toshio; Umeda, Takateru (Univ. of Tokyo (Japan). Dept. of Metallurgy)

    1994-12-01

    A numerical analysis of the microstructural evolution of microcellular and cellular [alpha]-Al phase in gas-atomized Al-8 wt pct Fe droplets was represented. The two-dimensional (2-D) non-Newtonian heat transfer and the dendritic growth theory in the undercooled melt were combined, assuming a point nucleation on the droplet surface and the macroscopically smooth solid-liquid interface enveloping the cell tips. It reproduced the main characteristic features of the reported microstructures quite well and predicted a considerable volume fraction of thermal dendritic growth region in a droplet smaller than 10[mu]m if an initial undercooling was larger than 100 K. The volume fractions of the microcellular region, g[sub A], and the sum of the microcellular and cellular region, g[sub [alpha

  16. Numerical Procedure to Forecast the Tsunami Parameters from a Database of Pre-Simulated Seismic Unit Sources

    Science.gov (United States)

    Jiménez, César; Carbonel, Carlos; Rojas, Joel

    2017-09-01

    We have implemented a numerical procedure to forecast the parameters of a tsunami, such as the arrival time of the front of the first wave and the maximum wave height in real and virtual tidal stations along the Peruvian coast, with this purpose a database of pre-computed synthetic tsunami waveforms (or Green functions) was obtained from numerical simulation of seismic unit sources (dimension: 50 × 50 km2) for subduction zones from southern Chile to northern Mexico. A bathymetry resolution of 30 arc-sec (approximately 927 m) was used. The resulting tsunami waveform is obtained from the superposition of synthetic waveforms corresponding to several seismic unit sources contained within the tsunami source geometry. The numerical procedure was applied to the Chilean tsunami of April 1, 2014. The results show a very good correlation for stations with wave amplitude greater than 1 m, in the case of the Arica tide station an error (from the maximum height of the observed and simulated waveform) of 3.5% was obtained, for Callao station the error was 12% and the largest error was in Chimbote with 53.5%, however, due to the low amplitude of the Chimbote wave (tsunami early warning, where speed is required rather than accuracy, so the results should be taken as preliminary.

  17. Numerical procedure for the vibration analysis of arbitrarily constrained stiffened panels with openings

    Directory of Open Access Journals (Sweden)

    Dae Seung Cho

    2014-12-01

    Full Text Available A simple and efficient vibration analysis procedure for stiffened panels with openings and arbitrary boundary conditions based on the assumed mode method is presented. Natural frequencies and modes are determined by solving an eigenvalue problem of a multi-degree-of-freedom system matrix equation derived by using Lagrange's equations of motion, where Mindlin theory is applied for plate and Timoshenko beam theory for stiffeners. The effect of stiffeners on vibration response is taken into account by adding their strain and kinetic energies to the corresponding plate energies whereas the strain and kinetic energies of openings are subtracted from the plate energies. Different stiffened panels with various opening shapes and dispositions for several combinations of boundary conditions are analyzed and the results show good agreement with those obtained by the finite element analysis. Hence, the proposed procedure is especially appropriate for use in the preliminary design stage of stiffened panels with openings.

  18. Numerical procedure for fluid-structure interaction with structure displacements limited by a rigid obstacle

    Directory of Open Access Journals (Sweden)

    Yakhlef O.

    2017-06-01

    Full Text Available A fixed point algorithmis proposed to solve a fluid-structure interaction problem with the supplementary constraint that the structure displacements are limited by a rigid obstacle. Fictitious domain approach with penalization is used for the fluid equations. The surface forces from the fluid acting on the structure are computed using the fluid solution in the structure domain. The continuity of the fluid and structure velocities is imposed through the penalization parameter. The constraint of non-penetration of the elastic structure into the rigid obstacle is treated weakly. A convex constrained optimization problem is solved in order to get the structure displacements. Numerical results are presented.

  19. An initialization procedure for assimilating geostationary satellite data into numerical weather prediction models

    Science.gov (United States)

    Gal-Chen, T.; Schmidt, B.; Uccellini, L. W.

    1985-01-01

    An attempt was made to offset the limitations of GEO satellites for supplying timely initialization data for numerical weather prediction models (NWP). The NWP considered combined an isentropic representation of the free atmosphere with a sigma-coordinate model for the lower 200 mb. A flux form of the predictive equations described vertical transport interactions at the boundary of the two model domains, thereby accounting for the poor vertical temperature and wind field resolution of GEO satellite data. A variational analysis approach was employed to insert low resolution satellite-sensed temperature data at varying rates. The model vertical resolution was limited to that available from the satellite. Test simulations demonstrated that accuracy increases with the frequency of data updates, e.g., every 0.5-1 hr. The tests also showed that extensive cloud cover negates the capabilities of IR sensors and that microwave sensors will be needed for temperature estimations for 500-1000 mb levels.

  20. Development of Eulerian numerical procedure for free surface toward plate-mantle simulation

    Science.gov (United States)

    Furuichi, M.; Kameyama, M.; Kageyama, A.

    2008-12-01

    In the geophysical simulation study, one of the great challenges is to reproduce a realistic plate tectonics with mantle convection simulation. We develop an Eulerian numerical scheme for the steady Stokes flow to solve the deformation of rigid material (plate tectonics) induced by thermal convection of soft fluid (mantle convection). Our simulation scheme combines (i) the multigrid method together with a fast and robust smoother algorithm named ACuTE by Kameyama et~al. (2005), and (ii) an low diffusive semi-Lagrangian advection algorithm named CIP-CSLR-CS by Furuichi et~al. (2008). Since it is easy to optimize in vectorization/parallelization, our method is suitable for large scale simulation. According to our recent study, in which we carry out the validity test of our simulation scheme for a large deformation problem by using the fluid rope coiling event, the current approach in the grid resolution of our large scale simulation successfully reproduces not only qualitative but also quantitative behavior of a deformation of curved rigid plate. This indicates that by introducing a proper treatment of a free surface, our scheme may solve the whole system of solid earth on the mechanical model including the surface deformations without serious quantitative errors. In this study, we are trying to simulate self-gravitationg motion of the Stokes flow as the free surface problem. It means that the spherical shape like the real earth is simulated in the Cartesian grid. We would like to show the development of our numerical treatment toward free surface problems.

  1. State and Federal project development procedures for bus rapid transit : managing differences and reducing implementation delays

    Science.gov (United States)

    2011-08-01

    This report documents an investigation into the transportation project development process in the : context of the implementation of bus rapid transit systems on the State Highway System as well as such : systems being part of the Federal New Starts ...

  2. A novel homogenization procedure to model the skin layers in LF numerical dosimetry

    Science.gov (United States)

    De Santis, Valerio; Chen, Xi Lin; Cruciani, Silvano; Campi, Tommaso; Feliziani, Mauro

    2016-06-01

    In this study we focus on the validity of the skin layer currently implemented in up-to-date human-body anatomical models employed in low frequency (LF) numerical dosimetry. Indeed, the several layers of the skin structure, i.e. the stratum corneum (SC), dermis, and epidermis are in these models embedded into a unique fairly-thick (2-3 mm) layer encompassing all of them. While a previous work from the authors showed that for normal-standing (or limb-non-touching) postures a single-layer skin model could conservatively estimate the peak electric field induced in the skin, at least a two-layer skin model comprising of the SC and the remaining skin layers should be used for limb-touching exposure scenarios. This implies notable efforts to discretize the tiny SC layer questioning the validity of current anatomical models. A novel strategy based on the homogenization of the several skin layers has been therefore proposed in order to eliminate the SC from the computational domain opening the doors to future LF magnetic applications even for limb-touching scenarios.

  3. An Alternative and Rapid Method for the Extraction of Nucleic Acids from Ixodid Ticks by Potassium Acetate Procedure

    Directory of Open Access Journals (Sweden)

    Islay Rodríguez

    2014-08-01

    Full Text Available Four variants of the potassium acetate procedure for DNA extraction from ixodid ticks at different stage of their life cycles were evaluated and compared with phenol-chloroform and ammonium hydroxide methods. The most rapid and most efficient variant was validated in the DNA extraction procedure from the engorged ticks collected from bovine, canine as well as from house ticks for the screening of Borrelia burgdorferi sensu lato, Anaplasma spp. and Babesia spp. The ammonium hydroxide procedure was used for non-engorged ticks. All the variants were efficient and allowed obtaining PCR-quality material according to the specific amplification of 16S rRNA gene fragment of the original tick. DNA extracted from the ticks under the study was tested by multiplex PCR for the screening of tick-borne pathogens. Anaplasma spp. and Babesia spp. amplification products were obtained from 29/48 extracts. Ammonium hydroxide protocol was not efficient for two extracts. Detection of amplification products from the PCR indicated that DNA had been successfully extracted. The potassium acetate procedure could be an alternative, rapid, and reliable method for DNA extraction from the ixodid ticks, mainly for poorly-resourced laboratories.

  4. Clean fog rapid procedure test of artificially and naturally polluted HVDC porcelain barrel insulators

    Energy Technology Data Exchange (ETDEWEB)

    Vlastos, A.E. (Univ. of Technology, Gothenberg (SE))

    1992-07-01

    The first question asked in this paper refers to the variation of the peak leakage current prior to the flashover and the variation of the time prior to flashover in the test of artificially polluted insulators when using the up-and-down method. To answer this question sums up the test procedure used in the up-and-down method. For each trial represented the insulator was again polluted artificially and then dried following the procedure described in the paper. Then the insulator was transported into the fog chamber and the voltage and fog was switched on simultaneously. In these experiments a low fog injection rate was used.

  5. Measurement of humic and fulvic acid concentrations and dissolution properties by a rapid batch procedure.

    NARCIS (Netherlands)

    Zomeren, van A.; Comans, R.N.J.

    2007-01-01

    Although humic substances (HS) strongly facilitate the transport of metals and hydrophobic organic contaminants in environmental systems, their measurement is hampered by the time-consuming nature of currently available methods for their isolation and purification. We present and apply a new rapid

  6. Numerous Numerals.

    Science.gov (United States)

    Henle, James M.

    This pamphlet consists of 17 brief chapters, each containing a discussion of a numeration system and a set of problems on the use of that system. The numeration systems used include Egyptian fractions, ordinary continued fractions and variants of that method, and systems using positive and negative bases. The book is informal and addressed to…

  7. Procedure to Determine Thermal Characteristics and Groundwater Influence in Heterogeneous Subsoil by an Enhanced Thermal Response Test and Numerical Modeling

    Science.gov (United States)

    Aranzabal, Nordin; Martos, Julio; Montero, Álvaro; Monreal, Llúcia; Soret, Jesús; Torres, José; García-Olcina, Raimundo

    2016-04-01

    Ground thermal conductivity and borehole thermal resistance are indispensable parameters for the optimal design of subsoil thermal processes and energy storage characterization. The standard method to determine these parameters is the Thermal Response Test (TRT) which results are evaluated by models considering the ground being homogeneous and isotropic. This method obtains an effective ground thermal conductivity which represents an average of the thermal conductivity along the different layers crossed by perforation. In order to obtain a ground thermal conductivity profile as a function of depth two additional key factors are required, first, a new significant data set: a temperature profile along the borehole; and second, a new analysis procedure to extract ground heterogeneity from the recorded data. This research work presents the results of an analysis procedure, complementing the standard TRT analysis, which allows to estimate the thermal conductivity profile from a temperature profile measured along the borehole during a TRT. In the analysis procedure, a 3D Finite Element Model (FEM) is used to fit simulation results with experimental data, by a set of iterative simulations. This methodology is applied to a data set obtained throughout a TRT of 1kW heat power injection in a 30m depth Borehole Heat Exchange (BHE) facility. A highly conductive layer have been detected and located at 25 m depth. In addition, a novel automated device to obtain temperature profiles along geothermal pipes with or without fluid flow is presented. This sensor system is intended to improve the standard TRT and it allows the collection of depth depending thermal characteristics of the subsoil geological structure. Currently, some studies are being conducted in double U-pipe borehole installations in order to improve previously introduced analysis procedure. From a numerical model simulation that takes into account advective effects is pretended to estimate underground water velocity

  8. A Rapid Selection Procedure for Simple Commercial Implementation of omega-Transaminase Reactions

    DEFF Research Database (Denmark)

    Gundersen Deslauriers, Maria; Tufvesson, Pär; Rackham, Emma J.

    2016-01-01

    A stepwise selection procedure is presented to quickly evaluate whether a given omega-transaminase reaction is suitable for a so-called "simple" scale-up for fast industrial implementation. Here "simple" is defined as a system without the need for extensive process development or specialized...

  9. A rapid and specific derivatization procedure to identify acyl-glucuronides by mass spectrometry.

    Science.gov (United States)

    Vaz, Alfin D N; Wang, Wei Wei; Bessire, Andrew J; Sharma, Raman; Hagen, Anne E

    2010-07-30

    A simple procedure is described to identify acyl-glucuronides by coupled liquid chromatography/mass spectrometry after derivatization to a hydroxamic acid with hydroxylamine. The reaction specificity obviates the need for isolation of the acyl-glucuronide from an extract. Glucuronides derived from carbamic acids, and alkyl- and aromatic amines, are inert to the derivatization reaction conditions, making the hydroxamic acid derivative a fingerprint for acyl-glucuronides. Copyright 2010 John Wiley & Sons, Ltd.

  10. Rapid analytical procedure for determination of mineral oils in edible oil by GC-FID.

    Science.gov (United States)

    Wrona, Magdalena; Pezo, Davinson; Nerin, Cristina

    2013-12-15

    A procedure for the determination of mineral oils in edible oil has been fully developed. The procedure consists of using a sulphuric acid-impregnated silica gel (SAISG) glass column to eliminate the fat matter. A chemical combustion of the fatty acids takes place, while the mineral oils are not affected by the sulphuric acid. The column is eluted with hexane using a vacuum pump and the final extract is concentrated and analysed by gas chromatography (GC) with flame ionisation detector (FID). The detection limit (LOD) and the quantification limit (LOQ) in hexane were 0.07 and 0.21 μg g(-1) respectively and the LOQ in vegetable oil was 1 μg g(-1). Only a few minutes were necessary for sample treatment to have a clean extract. The efficiency of the process, measured through the recoveries from spiked samples of edible oil was higher than 95%. The procedure has been applied to determine mineral oil in olive oil from the retailed market. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. A non-linear procedure for the numerical analysis of crack development in beams failing in shear

    Directory of Open Access Journals (Sweden)

    P. Bernardi

    2016-01-01

    Full Text Available In this work, a consistent formulation for the representation of concrete behavior before and after cracking has been implemented into a non-linear model for the analysis of reinforced concrete structures, named 2D-PARC. Several researches have indeed pointed out that the adoption of an effective modeling for concrete, combined with an accurate failure criterion, is crucial for the correct prediction of the structural behavior, not only in terms of failure load, but also with reference to a realistic representation of crack initiation and development. This last aspect is particularly relevant at serviceability conditions in order to verify the fulfillment of structural requirements provided by Design Codes, which limit the maximum crack width due to appearance and durability issues. In more details, a constitutive model originally proposed by Ottosen and based on non-linear elasticity has been here incorporated into 2D-PARC in order to improve the numerical efficiency of the adopted algorithm, providing at the same time an accurate prediction of the structural response. The effectiveness of this procedure has been verified against significant experimental results available in the technical literature and relative to reinforced concrete beams without stirrups failing in shear, which represent a problem of great theoretical and practical importance in the field of structural engineering. Numerical results have been compared to experimental evidences not only in terms of global structural response (i.e. applied load vs. midspan deflection, but also in terms of crack pattern evolution and maximum crack widths.

  12. CAD – CAM PROCEDURE USING FOR RAPID PROTOTYPING WITH APPLICATION IN BIOMECHANICS

    Directory of Open Access Journals (Sweden)

    BRAUN Barbu

    2015-06-01

    Full Text Available The paper presents a new and efficient method for modeling some components with application in Biomechanics. It is shown the way in which this method could be successfully applied for orthopedic shoes, namely for foot insoles to correct any plantar deformities. The main advantages of the proposed method refer to low costs, successfully applying for different products for Biomechanics. The prototyped models via CAD/CAM method allowed a rapid and efficient improvement of their design. Another advantage refer to the fact that these can be properly and efficiently tested before prototyping by the point of view of mechanical stress, due to prior simulations, eliminating all costs meaning wastes or adjustments.

  13. Rapid and simple procedure for visualization of amphibian skeletons for teratological studies

    Energy Technology Data Exchange (ETDEWEB)

    Newman, S.M. Jr.; Dugan, T.S.; Dumont, J.N.

    1983-07-01

    A method for Alizarin red S and Alcian blue 8GX double staining of ossified and cartilagenous skeletal components has been developed for late larval and newly metamorphosed stages of Xenopus laevis. This technique, which utilizes fixed specimens, employs hydrogen peroxide bleaching, potassium hydroxide maceration, and ethanol/glycerin clearing, has proved convenient with many possible stopping points and the capability of producing assayable skeletons in only two and one-half days. The method routinely produces stained skeletons with excellent contrast and brilliant colors for photographics. This procedure was developed in conjunction with the use of late larvae of Xenopus as teratological test animals. The sensitivity and uniformity of response of this biological system and the capabilities of this skeletal technique provide an excellent system for the study of teratogenic effects on the development of ossified bone and skeletal conformation.

  14. A rapid procedure to ascertain the antimicrobial efficacy of oral care formulations.

    Science.gov (United States)

    Sreenivasan, P K; Tambs, G; Gittins, E; Nabi, N; Gaffar, A

    2003-12-01

    A rapid method examining the antimicrobial efficacy of oral care formulations with alamar blue, an oxidation-reduction dye with fluorescent end-points, is described. Significant correlations between increasing viable plate counts of the oral bacteria Actinomyces viscosus, Streptococcus sanguis, Streptococcus mutans and Actinobacillus actinomycetemcomitans and increased alamar fluorescence were noted. Metabolically active bacteria reduced alamar with the reduced dye found in the cell-free filtrate. Insignificant alamar reductions were noted in the absence of bacteria or by spent culture supernatants. The efficacy of mouthrinses with clinically proven antiplaque agents such as chlorhexidine or cetylpyridinium chloride were determined by alamar blue. In a model system with A. viscosus, triclosan dentifrices demonstrate a dose-dependent effect on bacteria. Human salivary bacteria demonstrate increasing alamar fluorescence with increasing plate counts. A clinical study examined the effects of rinsing with chlorhexidine or cetylpyridinium chloride mouthrinses in comparison with a placebo mouthrinse and water on salivary bacteria. Rinsing with chlorhexidine resulted in the least number of bacteria by alamar and plate count methods. In summary, the current study demonstrates the utility of alamar blue to examine the antimicrobial effects of oral care formulations in laboratory and clinical studies.

  15. Validation of the rapid assessment procedure for loiasis (RAPLOA in the democratic republic of Congo

    Directory of Open Access Journals (Sweden)

    Wanji Samuel

    2012-02-01

    Full Text Available Abstract Background A simple method called RAPLOA, to rapidly assess what proportion of people in a community are infected with L. loa and hence which communities are at high risk of severe adverse reactions following ivermectin treatment, was developed in Cameroon and Nigeria. The method needed further validation in other geographical and cultural contexts before its application in all endemic countries. The present study was designed to validate RAPLOA in two regions in the North East and South West of the Democratic Republic of Congo. Methods In each study region, villages were selected from different bio-ecological zones in order to cover a wide range of loiasis endemicity. In each selected community, 80 people above the age of 15 years were interviewed for a history of eye worm (migration of adult L. loa under the conjunctiva of the eye and parasitologically examined for the presence and intensity of L. loa infection. In total, 8100 individuals from 99 villages were enrolled into the study. Results The results confirmed the findings of the original RAPLOA study: i the eye worm phenomenon was well-known in all endemic areas, ii there was a clear relationship between the prevalence of eye worm history and the prevalence and intensity of L. loa microfilaraemia, and iii using a threshold of 40%, the prevalence of eye worm history was a sensitive and specific indicator of high-risk communities. Conclusion Following this successful validation, RAPLOA was recommended for the assessment of loiasis endemicity in areas targeted for ivermectin treatment by lymphatic filariasis and onchocerciasis control programmes.

  16. A robust interpolation procedure for producing tidal current ellipse inputs for regional and coastal ocean numerical models

    Science.gov (United States)

    Byun, Do-Seong; Hart, Deirdre E.

    2017-04-01

    Regional and/or coastal ocean models can use tidal current harmonic forcing, together with tidal harmonic forcing along open boundaries in order to successfully simulate tides and tidal currents. These inputs can be freely generated using online open-access data, but the data produced are not always at the resolution required for regional or coastal models. Subsequent interpolation procedures can produce tidal current forcing data errors for parts of the world's coastal ocean where tidal ellipse inclinations and phases move across the invisible mathematical "boundaries" between 359° and 0° degrees (or 179° and 0°). In nature, such "boundaries" are in fact smooth transitions, but if these mathematical "boundaries" are not treated correctly during interpolation, they can produce inaccurate input data and hamper the accurate simulation of tidal currents in regional and coastal ocean models. These avoidable errors arise due to procedural shortcomings involving vector embodiment problems (i.e., how a vector is represented mathematically, for example as velocities or as coordinates). Automated solutions for producing correct tidal ellipse parameter input data are possible if a series of steps are followed correctly, including the use of Cartesian coordinates during interpolation. This note comprises the first published description of scenarios where tidal ellipse parameter interpolation errors can arise, and of a procedure to successfully avoid these errors when generating tidal inputs for regional and/or coastal ocean numerical models. We explain how a straightforward sequence of data production, format conversion, interpolation, and format reconversion steps may be used to check for the potential occurrence and avoidance of tidal ellipse interpolation and phase errors. This sequence is demonstrated via a case study of the M2 tidal constituent in the seas around Korea but is designed to be universally applicable. We also recommend employing tidal ellipse parameter

  17. Numerical study of RF exposure and the resulting temperature rise in the foetus during a magnetic resonance procedure

    Energy Technology Data Exchange (ETDEWEB)

    Hand, J W; Li, Y; Hajnal, J V [Imaging Sciences Department, Imperial College London (Hammersmith Campus), London W12 0NN (United Kingdom)], E-mail: j.hand@imperial.ac.uk

    2010-02-21

    Numerical simulations of specific absorption rate (SAR) and temperature changes in a 26-week pregnant woman model within typical birdcage body coils as used in 1.5 T and 3 T MRI scanners are described. Spatial distributions of SAR and the resulting spatial and temporal changes in temperature are determined using a finite difference time domain method and a finite difference bio-heat transfer solver that accounts for discrete vessels. Heat transfer from foetus to placenta via the umbilical vein and arteries as well as that across the foetal skin/amniotic fluid/uterine wall boundaries is modelled. Results suggest that for procedures compliant with IEC normal mode conditions (maternal whole-body averaged SAR{sub MWB} {<=} 2 W kg{sup -1} (continuous or time-averaged over 6 min)), whole foetal SAR, local foetal SAR{sub 10g} and average foetal temperature are within international safety limits. For continuous RF exposure at SAR{sub MWB} = 2 W kg{sup -1} over periods of 7.5 min or longer, a maximum local foetal temperature >38 deg. C may occur. However, assessment of the risk posed by such maximum temperatures predicted in a static model is difficult because of frequent foetal movement. Results also confirm that when SAR{sub MWB} = 2 W kg{sup -1}, some local SAR{sub 10g} values in the mother's trunk and extremities exceed recommended limits.

  18. Aberration measurement in HRTEM: Implementation and diagnostic use of numerical procedures for the highly precise recognition of diffractogram patterns

    Energy Technology Data Exchange (ETDEWEB)

    Barthel, J. [Institute of Solid State Research and Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C), Forschungszentrum Juelich GmbH, D-52425 Juelich (Germany); Thust, A., E-mail: a.thust@fz-juelich.de [Institute of Solid State Research and Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C), Forschungszentrum Juelich GmbH, D-52425 Juelich (Germany)

    2010-12-15

    The precise characterisation of the instrumental imaging properties in the form of aberration parameters constitutes an almost universal necessity in quantitative HRTEM, and is underlying most hardware and software techniques established in this field. We focus in this paper on the numerical analysis of individual diffractograms as a first preparatory step for further publications on HRTEM aberration measurement. The extraction of the defocus and the 2-fold astigmatism from a diffractogram is a classical pattern recognition problem, which we believe to have solved in a near-optimum way concerning precision, speed, and robustness. The newly gained measurement precision allows us to resolve fluctuations of the defocus and the 2-fold astigmatism and to assess thereby the optical stability of electron microscopes. Quantitative stability criteria are elaborated, which may serve as helpful guidelines for daily work as well as for microscope acceptance tests. -- Research Highlights: {yields} Algorithms for the highly precise diffractogram analysis in HRTEM are introduced. {yields} AMADEUS procedure measures defocus and astigmatism with a few Angstrom precision. {yields} Aberration measurement meets the precision requirements of 0.5 A microscopy. {yields} Quantitative criteria for the optical stability of HRTEMs are introduced.

  19. A rapid in situ procedure for determination of bacterial susceptibility or resistance to antibiotics that inhibit peptidoglycan biosynthesis

    Directory of Open Access Journals (Sweden)

    Bou Germán

    2011-08-01

    Full Text Available Abstract Background Antibiotics which inhibit bacterial peptidoglycan biosynthesis are the most widely used in current clinical practice. Nevertheless, resistant strains increase dramatically, with serious economic impact and effects on public health, and are responsible for thousands of deaths each year. Critical clinical situations should benefit from a rapid procedure to evaluate the sensitivity or resistance to antibiotics that act at the cell wall. We have adapted a kit for rapid determination of bacterial DNA fragmentation, to assess cell wall integrity. Results Cells incubated with the antibiotic were embedded in an agarose microgel on a slide, incubated in an adapted lysis buffer, stained with a DNA fluorochrome, SYBR Gold and observed under fluorescence microscopy. The lysis affects the cells differentially, depending on the integrity of the wall. If the bacterium is susceptible to the antibiotic, the weakened cell wall is affected by the lysing solution so the nucleoid of DNA contained inside the bacterium is released and spread. Alternatively, if the bacterium is resistant to the antibiotic, it is practically unaffected by the lysis solution and does not liberate the nucleoid, retaining its normal morphological appearance. In an initial approach, the procedure accurately discriminates susceptible, intermediate and resistant strains of Escherichia coli to amoxicillin/clavulanic acid. When the bacteria came from an exponentially growing liquid culture, the effect on the cell wall of the β-lactam was evident much earlier that when they came from an agar plate. A dose-response experiment with an E. coli strain susceptible to ampicillin demonstrated a weak effect before the MIC dose. The cell wall damage was not homogenous among the different cells, but the level of damage increased as dose increased with a predominant degree of effect for each dose. A microgranular-fibrilar extracellular background was evident in gram

  20. Rapid procedure for coupling of protein antigens to red cells to be used in plaque assays by prewashing in chromium chloride

    NARCIS (Netherlands)

    Savelkoul, H.F.J.; Greeve, A.A.M.; Rijkers, G.T.; Marwitz, P.A.; Benner, R.

    1988-01-01

    A rapid and efficient procedure is described for the coupling of proteins (protein A, provalbumin, albumin and chicken gamma globulin) to sheep red blood cells (SRBC) to be used in antigen-specific or protein A plaque assays. This modification of the original procedure has three distinct features:

  1. An economic and rapid diagnostic procedure for the detection of salmonella/shigella using the polyvalent salmonella phage O-1.

    Science.gov (United States)

    Fey, H; Bürgi, E; Margadant, A; Boller, E

    1978-01-01

    An easy, rapid and economic two-step procedure is described for the detection of Salmonella/Shigella. In the first step the susceptibility of suspected colonies for the phage O-1 of FELIX and CALLOW is tested. Positive cultures are serologically confirmed. The test is performed on Triple Sugar Iron Agar and lasts 4-6 hrs. Phage negative cultures which are lactose- and sucrose negative are tested for lysine decarboxylase and, if Shigella is possible (i.e. in human material on primary plates), for indol production and motility in a semisolid tryptophane agar. Of 22880 Salmonella straine 21977, i.e. 96.1% were phage-sensitive. Strains belonging to certain O-groups (OE) or species are lysed at a lower percentage. However, since they are lysine decarboxylase positive they are not lost and can be submitted to a serological examination.

  2. Development of a numerical procedure for mixed mode K-solutions and fatigue crack growth in FCC single crystal superalloys

    Science.gov (United States)

    Ranjan, Srikant

    2005-11-01

    Fatigue-induced failures in aircraft gas turbine and rocket engine turbopump blades and vanes are a pervasive problem. Turbine blades and vanes represent perhaps the most demanding structural applications due to the combination of high operating temperature, corrosive environment, high monotonic and cyclic stresses, long expected component lifetimes and the enormous consequence of structural failure. Single crystal nickel-base superalloy turbine blades are being utilized in rocket engine turbopumps and jet engines because of their superior creep, stress rupture, melt resistance, and thermomechanical fatigue capabilities over polycrystalline alloys. These materials have orthotropic properties making the position of the crystal lattice relative to the part geometry a significant factor in the overall analysis. Computation of stress intensity factors (SIFs) and the ability to model fatigue crack growth rate at single crystal cracks subject to mixed-mode loading conditions are important parts of developing a mechanistically based life prediction for these complex alloys. A general numerical procedure has been developed to calculate SIFs for a crack in a general anisotropic linear elastic material subject to mixed-mode loading conditions, using three-dimensional finite element analysis (FEA). The procedure does not require an a priori assumption of plane stress or plane strain conditions. The SIFs KI, KII, and KIII are shown to be a complex function of the coupled 3D crack tip displacement field. A comprehensive study of variation of SIFs as a function of crystallographic orientation, crack length, and mode-mixity ratios is presented, based on the 3D elastic orthotropic finite element modeling of tensile and Brazilian Disc (BD) specimens in specific crystal orientations. Variation of SIF through the thickness of the specimens is also analyzed. The resolved shear stress intensity coefficient or effective SIF, Krss, can be computed as a function of crack tip SIFs and the

  3. Innovative procedure for computer-assisted genioplasty: three-dimensional cephalometry, rapid-prototyping model and surgical splint.

    Science.gov (United States)

    Olszewski, R; Tranduy, K; Reychler, H

    2010-07-01

    The authors present a new procedure of computer-assisted genioplasty. They determined the anterior, posterior and inferior limits of the chin in relation to the skull and face with the newly developed and validated three-dimensional cephalometric planar analysis (ACRO 3D). Virtual planning of the osteotomy lines was carried out with Mimics (Materialize) software. The authors built a three-dimensional rapid-prototyping multi-position model of the chin area from a medical low-dose CT scan. The transfer of virtual information to the operating room consisted of two elements. First, the titanium plates on the 3D RP model were pre-bent. Second, a surgical guide for the transfer of the osteotomy lines and the positions of the screws to the operating room was manufactured. The authors present the first case of the use of this model on a patient. The postoperative results are promising, and the technique is fast and easy-to-use. More patients are needed for a definitive clinical validation of this procedure. Copyright 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  4. [Rapid and Dynamic Determination Models of Amino Acids and Catechins Concentrations during the Processing Procedures of Keemun Black Tea].

    Science.gov (United States)

    Ning, Jing-ming; Yan, Ling; Zhang, Zheng-zhu; Wei, Ling-dong; Li, Lu-qing; Fang, Jun-ting; Huang, Cai-wang

    2015-12-01

    Tea is one of the most popular beverages in the world. For the contribution to the taste and healthy functions of tea, amino acids and catechins are important components. Among different kinds of black teas in the world, Keemun black tea has the famous and specific fragrance, "Keemun aroma". During the processing procedure of Keemun black tea, the contents of amino acids and catechins changed greatly, and the differences of these concentrations during processing varied significantly. However, a rapid and dynamic determination method during the processing procedure was not existed up to now. In order to find out a rapid determination method for the contents of amino acids and catechins during the processing procedure of Keemun black tea, the materials of fresh leaves, withered leaves, twisted leaves, fermented leaves, and crude tea (after drying) were selected to acquire their corresponding near infrared spectroscopy and obtain their contents of amino acids and catechins by chemical analysis method. The original spectra data were preprocessed by the Standard Normal Variate Transformation (SNVT) method. And the model of Near Infrared (NIR) spectroscopy with the contents of amino acids and catechins combined with Synergy Interval Partial Least squares (Si-PLS) was established in this study. The correlation coefficients and the cross validation root mean square error are treated as the efficient indexes for evaluating models. The results showed that the optimal prediction model of amino acids by Si-PLS contained 20 spectral intervals combined with 4 subintervals and 9 principal component factors. The correlation coefficient and the root mean square error of the calibration set were 0. 955 8 and 1. 768, respectively; the correlation coefficient and the root mean square error of the prediction set were 0. 949 5 and 2. 16, respectively. And the optimal prediction model of catechins by Si-PLS contained 20 spectral intervals combined with 3 subintervals and 10 principal

  5. A rapid numerical method for solving Serre-Green-Naghdi equations describing long free surface gravity waves

    Science.gov (United States)

    Favrie, N.; Gavrilyuk, S.

    2017-07-01

    A new numerical method for solving the Serre-Green-Naghdi (SGN) equations describing dispersive waves on shallow water is proposed. From the mathematical point of view, the SGN equations are the Euler-Lagrange equations for a ‘master’ lagrangian submitted to a differential constraint which is the mass conservation law. One major numerical challenge in solving the SGN equations is the resolution of an elliptic problem at each time instant. This is the most time-consuming part of the numerical method. The idea is to replace the ‘master’ lagrangian by a one-parameter family of ‘augmented’ lagrangians, depending on a greater number of variables, for which the corresponding Euler-Lagrange equations are hyperbolic. In such an approach, the ‘master’ lagrangian is recovered by the augmented lagrangian in some limit (for example, when the corresponding parameter is large). The choice of such a family of augmented lagrangians is proposed and discussed. The corresponding hyperbolic system is numerically solved by a Godunov type method. Numerical solutions are compared with exact solutions to the SGN equations. It appears that the computational time in solving the hyperbolic system is much lower than in the case where the elliptic operator is inverted. The new method is applied, in particular, to the study of ‘Favre waves’ representing non-stationary undular bores produced after reflection of the fluid flow with a free surface at an immobile wall.

  6. Effect of annealing procedure on the bonding of ceramic to cobalt-chromium alloys fabricated by rapid prototyping.

    Science.gov (United States)

    Tulga, Ayca

    2017-08-22

    An annealing procedure is a heat treatment process to improve the mechanical properties of cobalt-chromium (Co-Cr) alloys. However, information is lacking about the effect of the annealing process on the bonding ability of ceramic to Co-Cr alloys fabricated by rapid prototyping. The purpose of this in vitro study was to evaluate the effects of the fabrication techniques and the annealing procedure on the shear bond strength of ceramic to Co-Cr alloys fabricated by different techniques. Ninety-six cylindrical specimens (10-mm diameter, 10-mm height) made of Co-Cr alloy were prepared by casting (C), milling (M), direct process powder-bed (LaserCUSING) with and without annealing (CL+, CL), and direct metal laser sintering (DMLS) with annealing (EL+) and without annealing (EL). After the application of ceramic to the metal specimens, the metal-ceramic bond strength was assessed using a shear force test at a crosshead speed of 0.5 mm/min. Shear bond strength values were statistically analyzed by 1-way ANOVA and Tukey multiple comparison tests (α=.05). Although statistically significant differences were found among the 3 groups (M, 29.87 ±2.06; EL, 38.92 ±2.04; and CL+, 40.93 ±2.21; P=.002), no significant differences were found among the others (P>.05). The debonding surfaces of all specimens exhibited mixed failure mode. These results showed that the direct process powder-bed method is promising in terms of metal-ceramic bonding ability. The manufacturing technique of Co-Cr alloys and the annealing process influence metal-ceramic bonding. Copyright © 2017 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  7. Rapid screening procedure to optimise the anaerobic codigestion of industrial biowastes and agricultural livestock wastes in Cyprus.

    Science.gov (United States)

    Monou, M; Kythreotou, N; Fatta, D; Smith, S R

    2009-02-01

    Small-scale experimental investigations were undertaken on the anaerobic digestion (AD) and codigestion of livestock waste and industrial biowastes. A simple procedure was developed to rapidly determine the suitability of wastes for digestion. The experiment was split into two phases; initially, the seed (digested brewery waste) was replaced by the test waste over a period of 5 days. During the second phase, the test waste was incubated and monitored for methanogenesis. Dairy cattle slurry was the most efficient co-substrate which, when codigested with pig slurry in an equal ratio achieved volatile solids destruction of 32%, CH(4) production rate of 97.4 ml d(-1), maximum CH(4) content of 61.6% and total gas yield of 2229 ml after 529 h. High fat content wastes were unsuitable for AD due to low pH value and because the dominant microbial reaction was fermentation. Codigestion was investigated to overcome any inhibitions; however, dairy cattle slurry, abattoir wastewater and NaOH additions did not lead to methanogenesis. Treating these wastes by AD is feasible but without CH(4) production.

  8. A rapid one-step kinetics-based immunoassay procedure for the highly-sensitive detection of C-reactive protein

    OpenAIRE

    sprotocols

    2014-01-01

    Authors: Sandeep Kumar Vashist, Gregor Czilwik, Thomas van Oordt, Felix von Stetten, Roland Zengerle, E. Marion Schneider & John H.T. Luong ### Abstract A rapid one-step kinetics-based sandwich enzyme-linked immunosorbent (ELISA) procedure has been developed for highly-sensitive detection of C-reactive protein (CRP) in less than 30 min. With minimal process steps, the procedure is highly simplified and cost-effective. The analysis only involves sequentially the formation of a sandwic...

  9. Detalhes singulares nos procedimentos operacionais da disjunção palatina Singular aspects to operate rapid palatal expansion procedures

    Directory of Open Access Journals (Sweden)

    Orlando Tanaka

    2004-08-01

    Full Text Available A disjunção palatina traz benefícios significativos nas más oclusões caracterizadas pela atresia esquelética do arco dentário superior. Desde os tempos de Angell muitos manuais foram criados com o intuito de orientar a instalação de aparelhos construídos em diferentes formatos e com materiais dos mais diversos fabricantes, utilizando, ainda, diferentes protocolos de ativação que objetivam a referida correção. A tecnologia utilizada para melhorar os materiais componentes dos aparelhos ortodônticos é muito importante mas os pequenos detalhes, que na verdade, não são pequenos, aliados aos conhecimentos científicos e ao bom senso devem ser observados, pois não se deve esperar que o aparelho "faça e resolva" tudo, corrigindo "num passe de mágica" as mordidas cruzadas posteriores. Este trabalho tem por objetivo detalhar as minúcias globais importantes, seja na confecção, na ativação e nos cuidados durante a permanência do disjuntor palatino na cavidade bucal.The rapid maxillary expansion procedure provide significant benefits in malocclusions with esqueletal posterior crossbites.Since Angell, lots of manuals were made in effort to guide the assembly of appliances from different types and employment of several techniques to obtain the desired correction. The technology used to improve the appliance materials is very important, but little details that actually are not so small together with scientific acknowledge and good sense must be regarded because one can not wait for the appliance “to do and solve” everything, correcting the posterior cross bites by a sleight-of-hand trick. The purpose of this report is to detail some little global aspects about construction, activation and concerns during the permanence period of the rapid maxillary expansion appliance in the mouth.

  10. An efficient and rapid DNA minipreparation procedure suitable for PCR/SSR and RAPD analyses in tropical forest tree species

    Directory of Open Access Journals (Sweden)

    Ana Lilia Alzate-Marin

    2009-10-01

    Full Text Available An efficient and rapid DNA minipreparation modified method for frozen samples was developed for five tropical tree species: Copaifera langsdorffii, Hymenaea courbaril, Eugenia uniflora, Tabebuia roseo alba and Cariniana estrellensis. This procedure that dispenses the use of liquid nitrogen, phenol and the addition of proteinase K, is an adaptation of the CTAB-based DNA extraction method. The modifications included the use of PVP to eliminate the polyphenols, only one chloroform-isoamyl alcohol step and the addition of RNase immediately after extraction with chloroform. The yields of the DNA samples ranged from 25.7 to 42.1 µg from 100 mg leaf tissue. The DNA samples extracted by this method were successfully used for PCR (SSR and RAPD analyses in these five and other twelve tropical tree species.Este trabalho teve como objetivo otimizar um protocolo econômico, rápido e eficaz de minipreparação de DNA genômico, para as espécies florestais Copaifera langsdorffii (Óleo de Copaíba, Hymenaea courbaril (Jatobá, Eugenia uniflora (Pitanga, Tabebuia roseo alba (Ipê Branco e Cariniana estrellensis (Jequitibá Branco. Este método é uma adaptação da técnica de extração CTAB de Doyle e Doyle (1990, o qual consiste principalmente na adição de PVP para eliminar polifenoles, somente uma etapa de extração com clorofórmio-álcool isoamílico e a adição da RNase A imediatamente após a extração com clorofórmio. O método também dispensa o uso de nitrogênio líquido, o uso do fenol e a adição de proteinase K. Os DNAs das espécies florestais extraídos apresentaram alto rendimento e boa qualidade, com rendimento de 25.7 a 42.1 µg de DNA a partir de 100 mg de tecido foliar congelado. Com este protocolo, em apenas 1 dia de trabalho, uma pessoa pode completar o isolamento do DNA de aproximadamente 50 amostras de folhas (dependendo da capacidade da centrífuga. O DNA obtido pode ser usado para métodos de análise baseados em PCR (SSR e

  11. A Robust Numerical Procedure for the Thermomechanical Flow Simulation of Friction Stir Welding Process Using an Adaptive Element-Free Galerkin Method

    Directory of Open Access Journals (Sweden)

    C. T. Wu

    2015-01-01

    Full Text Available A meshfree modeling technique of material flow in the three-dimensional multiphysics thermomechanical friction stir welding process is presented. In this numerical model, the discretization in space is derived by the Element-Free Galerkin method using a Lagrangian meshfree convex approximation. The discrete thermal and mechanical equations are weakly coupled as the time advances using a forward difference scheme. A mortar contact algorithm is employed to model the stirring effect and heat generation due to frictional contact. Heat conductance between contacting bodies is considered as a function of contact pressure. A two-way adaptive procedure is introduced to the coupled thermomechanical system to surpass potential numerical problems associated with the extensive material deformation and spatial discretization. In each adaptive phase, a consistent projection operation utilizing the first-order meshfree convex approximation is performed to remap the solution variables. Finally, a three-dimensional multiphysics thermomechanical coupled friction stir welding problem is analyzed to demonstrate the effectiveness of the present meshfree numerical procedure.

  12. Rapid fluvial incision of a late Holocene lava flow: Insights from LiDAR, alluvial stratigraphy, and numerical modeling

    Science.gov (United States)

    Sweeney, Kristin; Roering, Joshua J.

    2016-01-01

    Volcanic eruptions fundamentally alter landscapes, paving over channels, decimating biota, and emplacing fresh, unweathered material. The fluvial incision of blocky lava flows is a geomorphic puzzle. First, high surface permeability and lack of sediment should preclude geomorphically effective surface runoff and dissection. Furthermore, past work has demonstrated the importance of extreme floods in driving incision via column toppling and plucking in columnar basalt, but it is unclear how incision occurs in systems where surface blocks are readily mobile. We examine rapid fluvial incision of the Collier lava flow, an andesitic Holocene lava flow in the High Cascades of Oregon. Since lava flow emplacement ∼1600 yr ago, White Branch Creek has incised bedrock gorges up to 8 m deep into the coherent core of the lava flow and deposited >0.2 km3 of sediment on the lava flow surface. Field observation points to a bimodal discharge regime in the channel, with evidence for both annual snowmelt runoff and outburst floods from Collier glacier, as well as historical evidence of vigorous glacial meltwater. To determine the range of discharge events capable of incision in White Branch Creek, we used a mechanistic model of fluvial abrasion. We show that the observed incision implies that moderate flows are capable of both initiating channel formation and sustaining incision. Our results have implications for the evolution of volcanic systems worldwide, where glaciation and/or mass wasting may accelerate fluvial processes by providing large amounts of sediment to otherwise porous, sediment-starved landscapes.

  13. Numerical study of a novel procedure for installing the tower and Rotor Nacelle Assembly of offshore wind turbines based on the inverted pendulum principle

    Science.gov (United States)

    Guachamin Acero, Wilson; Gao, Zhen; Moan, Torgeir

    2017-09-01

    Current installation costs of offshore wind turbines (OWTs) are high and profit margins in the offshore wind energy sector are low, it is thus necessary to develop installation methods that are more efficient and practical. This paper presents a numerical study (based on a global response analysis of marine operations) of a novel procedure for installing the tower and Rotor Nacelle Assemblies (RNAs) on bottom-fixed foundations of OWTs. The installation procedure is based on the inverted pendulum principle. A cargo barge is used to transport the OWT assembly in a horizontal position to the site, and a medium-size Heavy Lift Vessel (HLV) is then employed to lift and up-end the OWT assembly using a special upending frame. The main advantage of this novel procedure is that the need for a huge HLV (in terms of lifting height and capacity) is eliminated. This novel method requires that the cargo barge is in the leeward side of the HLV (which can be positioned with the best heading) during the entire installation. This is to benefit from shielding effects of the HLV on the motions of the cargo barge, so the foundations need to be installed with a specific heading based on wave direction statistics of the site and a typical installation season. Following a systematic approach based on numerical simulations of actual operations, potential critical installation activities, corresponding critical events, and limiting (response) parameters are identified. In addition, operational limits for some of the limiting parameters are established in terms of allowable limits of sea states. Following a preliminary assessment of these operational limits, the duration of the entire operation, the equipment used, and weather- and water depth-sensitivity, this novel procedure is demonstrated to be viable.

  14. Numerical simulation for horizontal subsurface flow constructed wetlands: A short review including geothermal effects and solution bounding in biodegradation procedures

    Science.gov (United States)

    Liolios, K.; Tsihrintzis, V.; Angelidis, P.; Georgiev, K.; Georgiev, I.

    2016-10-01

    Current developments on modeling of groundwater flow and contaminant transport and removal in the porous media of Horizontal Subsurface Flow Constructed Wetlands (HSF CWs) are first reviewed in a short way. The two usual environmental engineering approaches, the black-box and the process-based one, are briefly presented. Next, recent research results obtained by using these two approaches are briefly discussed as application examples, where emphasis is given to the evaluation of the optimal design and operation parameters concerning HSF CWs. For the black-box approach, the use of Artificial Neural Networks is discussed for the formulation of models, which predict the removal performance of HSF CWs. A novel mathematical prove is presented, which concerns the dependence of the first-order removal coefficient on the Temperature and the Hydraulic Residence Time. For the process-based approach, an application example is first discussed which concerns procedures to evaluate the optimal range of values for the removal coefficient, dependent on either the Temperature or the Hydraulic Residence Time. This evaluation is based on simulating available experimental results of pilot-scale units operated in Democritus University of Thrace, Xanthi, Greece. Further, in a second example, a novel enlargement of the system of Partial Differential Equations is presented, in order to include geothermal effects. Finally, in a third example, the case of parameters uncertainty concerning biodegradation procedures is considered and the use of upper and a novel approach is presented, which concerns the upper and the lower solution bound for the practical draft design of HSF CWs.

  15. Towards the geophysical regime in numerical dynamo models: studies of rapidly-rotating convection driven dynamos with low Pm and constant heat flux boundary conditions

    DEFF Research Database (Denmark)

    Sheyko, A.A.; Finlay, Chris; Marti, P.

    We present a set of numerical dynamo models with the convection strength varied by a factor of 30 and the ratio of magnetic to viscous diffusivities by a factor of 20 at rapid rotation rates (E =nu/(2 Omega d^2 ) = 10-6 and 10-7 ) using a heat flux outer BC. This regime has been little explored...... on the structure of the dynamos and how this changes in relation to the selection of control parameters, a comparison with the proposed rotating convection and dynamo scaling laws, energy spectra of steady solutions and inner core rotation rates. Magnetic field on the CMB. E=2.959*10-7, Ra=6591.0, Pm=0.05, Pr=1....

  16. Numerical analysis of the Balitsky-Kovchegov equation with running coupling: dependence of the saturation scale on nuclear size and rapidity

    CERN Document Server

    Albacete, J L; Milhano, J G; Salgado, C A; Wiedemann, Urs Achim

    2005-01-01

    We study the effects of including a running coupling constant in high-density QCD evolution. For fixed coupling constant, QCD evolution preserves the initial dependence of the saturation momentum $Q_s$ on the nuclear size $A$ and results in an exponential dependence on rapidity $Y$, $Q^2_s(Y) = Q^2_s(Y_0) \\exp{[ \\bar\\alpha_s d (Y-Y_0) ]}$. For the running coupling case, we re-derive analytical estimates for the $A$- and $Y$-dependences of the saturation scale and test them numerically. The $A$-dependence of $Q_s$ vanishes $\\propto 1/ \\sqrt{Y}$ for large $A$ and $Y$. The $Y$-dependence is reduced to $Q_s^2(Y) \\propto \\exp{(\\Delta^\\prime\\sqrt{Y+X})}$ where we find numerically $\\Delta^\\prime\\simeq 3.2$, approximately 12% smaller than analytical estimates. In contrast to previous analytical work, we find a marked difference between the anomalous dimension $1-\\gamma$ governing the large transverse momentum behaviour of the gluon distribution for fixed coupling ($\\gamma \\simeq 0.65$) and for running coupling ($\\gam...

  17. Rapid Microwave Digestion Procedures for the Elemental Analysis of Alloy and Slag Samples of Smelted Ocean Bed Polymetallic Nodules

    Directory of Open Access Journals (Sweden)

    Kumari Smita

    2013-01-01

    Full Text Available The use of microwave digester for digestion of alloy and slag samples of smelted ocean bed polymetallic nodules has permitted the complete digestion of samples, thereby replacing the tedious classical methods of digestion of samples. The digestion procedure includes two acid-closed digestions of samples in a microwave oven. Owing to the hazardous nature of perchloric acid, it was not used in developed digestion procedure. Digested sample solutions were analyzed for concentrations of various radicals and the effectiveness of the developed digestion methodology was tested using certified reference materials. It was found that the developed method is giving results comparable with that obtained from conventionally digested samples. In this digestion procedure, time required for digestion of samples was reduced to about 1 hour only from 8-9 hours of conventional digestion.

  18. Developing and Validating a Rapid Small-Scale Column Test Procedure for GAC Selection using Reconstituted Lyophilized NOM

    Science.gov (United States)

    Cost effective design and operation of Granular Activated Carbon (GAC) facilities requires the selection of GAC that is optimal for a specific site. Rapid small-scale column tests (RSSCTs) are widely used for GAC assessment due to several advantages, including the ability to simu...

  19. Adapting a Markov Monte Carlo simulation model for forecasting the number of coronary artery revascularisation procedures in an era of rapidly changing technology and policy.

    Science.gov (United States)

    Mannan, Haider R; Knuiman, Matthew; Hobbs, Michael

    2008-06-25

    Treatments for coronary heart disease (CHD) have evolved rapidly over the last 15 years with considerable change in the number and effectiveness of both medical and surgical treatments. This period has seen the rapid development and uptake of statin drugs and coronary artery revascularization procedures (CARPs) that include Coronary Artery Bypass Graft procedures (CABGs) and Percutaneous Coronary Interventions (PCIs). It is difficult in an era of such rapid change to accurately forecast requirements for treatment services such as CARPs. In a previous paper we have described and outlined the use of a Markov Monte Carlo simulation model for analyzing and predicting the requirements for CARPs for the population of Western Australia (Mannan et al, 2007). In this paper, we expand on the use of this model for forecasting CARPs in Western Australia with a focus on the lack of adequate performance of the (standard) model for forecasting CARPs in a period during the mid 1990s when there were considerable changes to CARP technology and implementation policy and an exploration and demonstration of how the standard model may be adapted to achieve better performance. Selected key CARP event model probabilities are modified based on information relating to changes in the effectiveness of CARPs from clinical trial evidence and an awareness of trends in policy and practice of CARPs. These modified model probabilities and the ones obtained by standard methods are used as inputs in our Markov simulation model. The projected numbers of CARPs in the population of Western Australia over 1995-99 only improve marginally when modifications to model probabilities are made to incorporate an increase in effectiveness of PCI procedures. However, the projected numbers improve substantially when, in addition, further modifications are incorporated that relate to the increased probability of a PCI procedure and the reduced probability of a CABG procedure stemming from changed CARP preference

  20. Numerical procedure for determining pressure limits on borehole instability problems; Procedimento numerico para determimacao dos limites de pressao em problemas de instabilidade de pocos de petroleo

    Energy Technology Data Exchange (ETDEWEB)

    Muller, A.L. [Pontificia Univ. Catolica do Rio de Janeiro (PUC-Rio), RJ (Brazil). Grupo de Tecnologia em Computacao Grafica (TecGraf); Vargas Junior, E.A. [Pontificia Univ. Catolica do Rio de Janeiro (PUC-Rio), RJ (Brazil). Dept. de Engenharia Civil; Vaz, L.E. [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Escola de Engenharia. Dept. de Mecanica Aplicada e Estruturas; Goncalves, C.J. [PETROBRAS, Rio de Janeiro, RJ (Brazil). Centro de Pesquisas (CENPES)

    2008-07-01

    In the boreholes projects, the minimization of the instability problems is extreme importance. In the boreholes instability analysis, two failure mechanisms are generally considered, namely, failure due to either tensile or compressive stresses. Considering these mechanisms, the correct determination of the lower and upper limits of pressures, generated by the drilling fluid in the walls of the boreholes, is an alternative for minimization of the instability problems. The mechanisms of compression or tensile failure can be described in terms of mechanical and fluid flow responses of the transient fluid mechanical coupling problem. This paper proposes a numerical procedure, using finite elements, of the coupled fluid mechanical processes, for automatically determining the lower and upper limits of pressures on the walls of borehole, to ensure, according assumptions and criteria of failure pre-established, the stability of the same. The automatic obtaining those values has the purpose of replace the approximate obtaining by trial and error processes. A hypothetical example of application is show, and from this, inferred considerations about the proposed procedure. (author)

  1. Pregnant mare serum gonadotropin. Rapid chromatographic procedures for the purification of intact hormone and isolation of subunits.

    Science.gov (United States)

    Moore, W T; Ward, D N

    1980-07-25

    A method exploiting hydroxylapatite chromatography was developed to purify pregnant mare serum gonadotropin (PMSG or eCG) to high biological activity from partially purified commerical preparations. In addition, an alternative method utilizing chromatography on quaternary aminoethyl (QAE)-Sephadex and Sephadex G-200 is also presented. Both procedures are capable of producing, from commerical material with a potency of approximately 2,500 IU/mg, a product in excess of 12,000 IU/mg. If care is taken in the selection of fractions from the hydroxylapatite chromatography, essentially purified material may be obtained in a single step. The best fraction from the QAE-Sephadex and G-200 chromatography procedure contains a minor impurity. Pregnant mare serum gonadotropin subunits were purified by a single chromatographic step from the foregoing preparations utilizing 6 M guanidine hydrochloride for dissociation, followed by chromatography on Sephadex G-75. Analytical data, including amino acid composition, carbohydrate composition. NH2-terminal amino acid determinations, and electrophoretic behavior of the subunits in sodium dodecyl sulfate polyacrylamide gel electrophoresis are presented.

  2. Incisor compliance following operative procedures: a rapid 3-D finite element analysis using micro-CT data.

    Science.gov (United States)

    Magne, Pascal; Tan, Derek T

    2008-02-01

    New methods are available for the rapid generation of 3-D finite element models of dental structures and restorations. Validation of these methods are required. The aim of the present study is to utilize stereolithography and surface-driven automatic meshing to generate models of specific restorative conditions, and to examine these models under loading. The data generated are compared to existing experimental data in an attempt to validate the model. An intact maxillary central incisor was digitized with a micro-CT scanner. Surface contours of enamel and dentin were fitted following tooth segmentation based on pixel density using an interactive medical image control system. Stereolithography (STL) files of enamel and dentin surfaces were then remeshed to reduce mesh density and imported in a rapid prototyping software, where Boolean operations were used to assure the interfacial mesh congruence (dentinoenamel junction) and simulate different tooth preparations (endodontic access, veneer, proximal, and Class III preparations) and restorations (Class III composites). The different parts were then imported in a finite element software package to create 3D solid models. A 50-N point load perpendicular to the tooth's long axis and centered on the incisal edge was applied either on the buccal or palatal surface. The surface strain was obtained from selected nodes corresponding to the location of the strain gauges in the validation experiments. The increase in crown flexure (compared to the unaltered tooth) ranged from near zero values (conservative endodontic access, removal of proximal enamel) to ca 10% (aggressive endodontic access, conservative Class III preparations), 23% and 34% (moderate and aggressive Class III preparations, respectively), and 91% (veneer preparation). Placement of Class III composite resin restorations resulted in 85% recovery of the original crown stiffness. 3D FEA data correlated well with existing experimental data. In two situations, smaller

  3. Rapid Ethical Assessment on Informed Consent Content and Procedure in Hintalo-Wajirat, Northern Ethiopia: A Qualitative Study.

    Science.gov (United States)

    Abay, Serebe; Addissie, Adamu; Davey, Gail; Farsides, Bobbie; Addissie, Thomas

    2016-01-01

    Informed consent is a key component of bio-medical research involving human participants. However, obtaining informed consent is challenging in low literacy and resource limited settings. Rapid Ethical Assessment (REA) can be used to contextualize and simplify consent information within a given study community. The current study aimed to explore the effects of social, cultural, and religious factors during informed consent process on a proposed HPV-serotype prevalence study. A qualitative community-based REA was conducted in Adigudom and Mynebri Kebeles, Northern Ethiopia, from July to August 2013. Data were collected by a multi-disciplinary team using open ended questions concerning informed consent components in relation to the parent study. The team conducted one-to-one In-Depth Interviews (IDI) and Focus Group Discussions (FGDs) with key informants and community members to collect data based on the themes of the study. Tape recorded data were transcribed in Tigrigna and then translated into English. Data were categorized and thematically analyzed using open coding and content analysis based on pre-defined themes. The REA study revealed a number of socio-cultural issues relevant to the proposed study. Low community awareness about health research, participant rights and cervical cancer were documented. Giving a vaginal sample for testing was considered to be highly embarrassing, whereas giving a blood sample made participants worry that they might be given a result without the possibility of treatment. Verbal consent was preferred to written consent for the proposed study. This rapid ethical assessment disclosed important socio-cultural issues which might act as barriers to informed decision making. The findings were important for contextual modification of the Information Sheet, and to guide the best consent process for the proposed study. Both are likely to have enabled participants to understand the informed consent better and consequently to comply with the

  4. Rapid Ethical Assessment on Informed Consent Content and Procedure in Hintalo-Wajirat, Northern Ethiopia: A Qualitative Study.

    Directory of Open Access Journals (Sweden)

    Serebe Abay

    Full Text Available Informed consent is a key component of bio-medical research involving human participants. However, obtaining informed consent is challenging in low literacy and resource limited settings. Rapid Ethical Assessment (REA can be used to contextualize and simplify consent information within a given study community. The current study aimed to explore the effects of social, cultural, and religious factors during informed consent process on a proposed HPV-serotype prevalence study.A qualitative community-based REA was conducted in Adigudom and Mynebri Kebeles, Northern Ethiopia, from July to August 2013. Data were collected by a multi-disciplinary team using open ended questions concerning informed consent components in relation to the parent study. The team conducted one-to-one In-Depth Interviews (IDI and Focus Group Discussions (FGDs with key informants and community members to collect data based on the themes of the study. Tape recorded data were transcribed in Tigrigna and then translated into English. Data were categorized and thematically analyzed using open coding and content analysis based on pre-defined themes.The REA study revealed a number of socio-cultural issues relevant to the proposed study. Low community awareness about health research, participant rights and cervical cancer were documented. Giving a vaginal sample for testing was considered to be highly embarrassing, whereas giving a blood sample made participants worry that they might be given a result without the possibility of treatment. Verbal consent was preferred to written consent for the proposed study.This rapid ethical assessment disclosed important socio-cultural issues which might act as barriers to informed decision making. The findings were important for contextual modification of the Information Sheet, and to guide the best consent process for the proposed study. Both are likely to have enabled participants to understand the informed consent better and consequently to

  5. One-step antibody immobilization-based rapid and highly-sensitive sandwich ELISA procedure for potential in vitro diagnostics

    Science.gov (United States)

    Vashist, Sandeep Kumar; Marion Schneider, E.; Lam, Edmond; Hrapovic, Sabahudin; Luong, John H. T.

    2014-01-01

    An improved enzyme-linked immunosorbent (ELISA) assay using one-step antibody immobilization has been developed for the detection of human fetuin A (HFA), a specific biomarker for atherosclerosis and hepatocellular carcinoma. The anti-HFA formed a stable complex with 3-aminopropyltriethoxysilane (APTES) by ionic and hydrophobic interactions. The complex adsorbed on microtiter plates exhibited a detection range of 4.9 pg mL−1 to 20 ng mL−1 HFA, with a limit of detection of 7 pg mL−1. Furthermore, an analytical sensitivity of 10 pg mL−1 was achieved, representing a 51-fold increase in sensitivity over the commercial sandwich ELISA kit. The results obtained for HFA spiked in diluted human whole blood and plasma showed the same precision as the commercial kit. When stored at 4°C in 0.1 M phosphate-buffered saline (PBS, pH 7.4), the anti-HFA bound microtiter plates displayed no significant decrease in their functional activity after two months. The new ELISA procedure was extended for the detection of C-reactive protein, human albumin and human lipocalin-2 with excellent analytical performance. PMID:24638258

  6. Protocol: a rapid and economical procedure for purification of plasmid or plant DNA with diverse applications in plant biology

    Directory of Open Access Journals (Sweden)

    Li Li

    2010-01-01

    Full Text Available Abstract Research in plant molecular biology involves DNA purification on a daily basis. Although different commercial kits enable convenient extraction of high-quality DNA from E. coli cells, PCR and agarose gel samples as well as plant tissues, each kit is designed for a particular type of DNA extraction work, and the cost of purchasing these kits over a long run can be considerable. Furthermore, a simple method for the isolation of binary plasmid from Agrobacterium tumefaciens cells with satisfactory yield is lacking. Here we describe an easy protocol using homemade silicon dioxide matrix and seven simple solutions for DNA extraction from E. coli and A. tumefaciens cells, PCR and restriction digests, agarose gel slices, and plant tissues. Compared with the commercial kits, this protocol allows rapid DNA purification from diverse sources with comparable yield and purity at negligible cost. Following this protocol, we have demonstrated: (1 DNA fragments as small as a MYC-epitope tag coding sequence can be successfully recovered from an agarose gel slice; (2 Miniprep DNA from E. coli can be eluted with as little as 5 μl water, leading to high DNA concentrations (>1 μg/μl for efficient biolistic bombardment of Arabidopsis seedlings, polyethylene glycol (PEG-mediated Arabidopsis protoplast transfection and maize protoplast electroporation; (3 Binary plasmid DNA prepared from A. tumefaciens is suitable for verification by restriction analysis without the need for large scale propagation; (4 High-quality genomic DNA is readily isolated from several plant species including Arabidopsis, tobacco and maize. Thus, the silicon dioxide matrix-based DNA purification protocol offers an easy, efficient and economical way to extract DNA for various purposes in plant research.

  7. Rapid isolation procedure for Δ9-tetrahydrocannabinolic acid A (THCA) from Cannabis sativa using two flash chromatography systems.

    Science.gov (United States)

    Wohlfarth, Ariane; Mahler, Hellmut; Auwärter, Volker

    2011-10-15

    Two isolation procedures for Δ9-tetrahydrocannabinolic acid A (THCA), the biogenetic precursor in the biosynthesis of the psychoactive Δ9-tetrahydrocannabinol (THC) in the cannabis plant, are presented. Two flash chromatography systems that can be used independently from each other were developed to separate THCA from other compounds of a crude cannabis extract. In both systems UV absorption at 209 and 270 nm was monitored. Purity was finally determined by HPLC-DAD, NMR and GC-MS analysis with a focus on the impurity THC. System 1 consisted of a normal phase silica column (120 g) as well as cyclohexane and acetone--both spiked with the modifier pyridine--as mobile phases. Gradient elution was performed over 15 min. After the chromatographic run the fractions containing THCA fractions were pooled, extracted with hydrochloric acid to eliminate pyridine and evaporated to dryness. Loading 1800 mg cannabis extract yielded 623 mg THCA with a purity of 99.8% and a THC concentration of 0.09%. System 2 was based on a reversed-phase C18 column (150 g) combined with 0.55% formic acid and methanol as mobile phases. A very flat gradient was set over 20 minutes. After pooling the THCA-containing fractions methanol was removed in a rotary evaporator. THCA was re-extracted from the remaining aqueous phase with methyl tert-butyl ether. The organic phase was finally evaporated under high vacuum conditions. Loading 300 mg cannabis extract yielded 51 mg THCA with a purity of 98.8% and a THC concentration of 0.67%. Copyright © 2011 Elsevier B.V. All rights reserved.

  8. Sediment source tracing in a lowland agricultural catchment in southern England using a modified procedure combining statistical analysis and numerical modelling.

    Science.gov (United States)

    Collins, A L; Zhang, Y; McChesney, D; Walling, D E; Haley, S M; Smith, P

    2012-01-01

    Catchment erosion, soil losses and resulting sediment pressures continue to represent cause for concern with respect to the ecological vitality and amenity value of riverine systems, including those in the agricultural catchments of southern England. Given that the sources of fine-grained sediment are typically diffuse in nature, it is essential to adopt a catchment-wide perspective to corresponding management strategies and sediment source tracing procedures have proved useful in assisting such planning. There remains, however, scope for further refining sediment sourcing procedures and on that basis, a recent study in the upper River Kennet (~214 km(2)) catchment in southern England, provided an opportunity for designing and testing a refined statistical procedure for sediment source discrimination with composite fingerprints using Genetic Algorithm (GA)-driven Discriminant Function Analysis, the Kruskal-Wallis H-test and Principal Components Analysis. The revised statistical verification of composite signatures was combined with numerical mass balance modelling using recent refinements including a range of tracer weightings and both local and GA optimisation. Comparison of the local and global optimisation increased confidence in the outputs of local optimisation and the goodness-of-fit for the predicted source contributions using the optimum composite signatures selected from the revised statistical testing ranged from 0.914 to 0.965. Overall relative frequency-weighted average median source type contributions were estimated to be 4% (agricultural topsoils; predicted deviate median inputs 1-19%), 55% (unmetalled farm track surfaces; predicted deviate median inputs 9-91%), 6% (damaged road verges; predicted deviate median inputs 4-42%), 31% (channel banks/subsurface sources; predicted deviate median inputs 5-41%) and 4% (urban street dust; predicted deviate median inputs 0-20%). The study provides further evidence of the importance of eroding farm tacks as a

  9. LSENS: A General Chemical Kinetics and Sensitivity Analysis Code for homogeneous gas-phase reactions. Part 1: Theory and numerical solution procedures

    Science.gov (United States)

    Radhakrishnan, Krishnan

    1994-01-01

    LSENS, the Lewis General Chemical Kinetics and Sensitivity Analysis Code, has been developed for solving complex, homogeneous, gas-phase chemical kinetics problems and contains sensitivity analysis for a variety of problems, including nonisothermal situations. This report is part 1 of a series of three reference publications that describe LENS, provide a detailed guide to its usage, and present many example problems. Part 1 derives the governing equations and describes the numerical solution procedures for the types of problems that can be solved. The accuracy and efficiency of LSENS are examined by means of various test problems, and comparisons with other methods and codes are presented. LSENS is a flexible, convenient, accurate, and efficient solver for chemical reaction problems such as static system; steady, one-dimensional, inviscid flow; reaction behind incident shock wave, including boundary layer correction; and perfectly stirred (highly backmixed) reactor. In addition, the chemical equilibrium state can be computed for the following assigned states: temperature and pressure, enthalpy and pressure, temperature and volume, and internal energy and volume. For static problems the code computes the sensitivity coefficients of the dependent variables and their temporal derivatives with respect to the initial values of the dependent variables and/or the three rate coefficient parameters of the chemical reactions.

  10. REPRINT OF: Aberration measurement in HRTEM: Implementation and diagnostic use of numerical procedures for the highly precise recognition of diffractogram patterns

    Energy Technology Data Exchange (ETDEWEB)

    Barthel, J. [Institute of Solid State Research and Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C), Forschungszentrum Juelich GmbH, D-52425 Juelich (Germany); Thust, A., E-mail: a.thust@fz-juelich.de [Institute of Solid State Research and Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C), Forschungszentrum Juelich GmbH, D-52425 Juelich (Germany)

    2011-06-15

    The precise characterisation of the instrumental imaging properties in the form of aberration parameters constitutes an almost universal necessity in quantitative HRTEM, and is underlying most hardware and software techniques established in this field. We focus in this paper on the numerical analysis of individual diffractograms as a first preparatory step for further publications on HRTEM aberration measurement. The extraction of the defocus and the 2-fold astigmatism from a diffractogram is a classical pattern recognition problem, which we believe to have solved in a near-optimum way concerning precision, speed, and robustness. The newly gained measurement precision allows us to resolve fluctuations of the defocus and the 2-fold astigmatism and to assess thereby the optical stability of electron microscopes. Quantitative stability criteria are elaborated, which may serve as helpful guidelines for daily work as well as for microscope acceptance tests. -- Research Highlights: {yields} Algorithms for the highly precise diffractogram analysis in HRTEM are introduced. {yields} AMADEUS procedure measures defocus and astigmatism with a few Angstrom precision. {yields} Aberration measurement meets the precision requirements of 0.5 A microscopy. {yields} Quantitative criteria for the optical stability of HRTEMs are introduced.

  11. Simplified NaCl based (68)Ga concentration and labeling procedure for rapid synthesis of (68)Ga radiopharmaceuticals in high radiochemical purity.

    Science.gov (United States)

    Mueller, Dirk; Klette, Ingo; Baum, Richard P; Gottschaldt, M; Schultz, Michael K; Breeman, Wouter A P

    2012-08-15

    A simple sodium chloride (NaCl) based (68)Ga eluate concentration and labeling method that enables rapid, high-efficiency labeling of DOTA conjugated peptides in high radiochemical purity is described. The method utilizes relatively few reagents and comprises minimal procedural steps. It is particularly well-suited for routine automated synthesis of clinical radiopharmaceuticals. For the (68)Ga generator eluate concentration step, commercially available cation-exchange cartridges and (68)Ga generators were used. The (68)Ga generator eluate was collected by use of a strong cation exchange cartridge. 98% of the total activity of (68)Ga was then eluted from the cation exchange cartridge with 0.5 mL of 5 M NaCl solution containing a small amount of 5.5 M HCl. After buffering with ammonium acetate, the eluate was used directly for radiolabeling of DOTATOC and DOTATATE. The (68)Ga-labeled peptides were obtained in higher radiochemical purity compared to other commonly used procedures, with radiochemical yields greater than 80%. The presence of (68)Ge could not be detected in the final product. The new method obviates the need for organic solvents, which eliminates the required quality control of the final product by gas chromatography, thereby reducing postsynthesis analytical effort significantly. The (68)Ga-labeled products were used directly, with no subsequent purification steps, such as solid-phase extraction. The NaCl method was further evaluated using an automated fluid handling system and it routinely facilitates radiochemical yields in excess of 65% in less than 15 min, with radiochemical purity consistently greater than 99% for the preparation of (68)Ga-DOTATOC.

  12. Rapid assessment procedure for loiasis and mapping lymphatic filariasis: two perfect illustrations of "to be in English or not to be".

    Science.gov (United States)

    Carme, Bernard

    2012-01-01

    Interest in filariasis has found a new impetus now that neglected tropical diseases have their own journal. However, some of the advances published in renowned international journals have completely ignored previous publications on the subject, particularly those in languages other than English. The rapid assessment procedure for loiasis and the mapping of lymphatic filariasis provide two perfect illustrations of this. This problem may seem a bit outdated, given that all "good authors" now publish exclusively in English. It certainly is outdated for most areas of medicine. But, surely, this should not be the case for neglected tropical diseases, for which certain long-standing findings are every bit as important as what may be presented as new discoveries. One possibility would be for certain journals, such as PLOS Neglected Tropical Diseases, to include a specific heading permitting the publication in English of older studies that initially appeared in a language other than English. The texts would be English versions respecting the entirety of the original text. Submission should be accompanied by a presentation of the problem, with details and explanatory comments, with submission at the initiative of the authors of the former article in question or their students or sympathizers.

  13. Ball's motion, sliding friction, and internal load distribution in a high-speed ball bearing subjected to a combined radial, thrust, and moment load, applied to the inner ring's center of mass: Numerical procedure

    Science.gov (United States)

    César Ricci, Mário

    2015-10-01

    In a companion paper of this was introduced a set of non-linear algebraic equations for ball's motion, sliding friction and internal loading distribution computation in a high-speed, single-row, angular-contact ball bearing, subjected to a known combined radial, thrust and moment load, which must be applied to the inner ring's center of mass. It was shown there that it is required the iterative solution of 9Z + 3 simultaneous non-linear equations - where Z is the number of balls - to yield exact solution for contact angles, ball attitude angles, rolling radii, normal contact deformations and axial, radial, and angular deflections of the inner ring with respect the outer ring. The Newton-Rhapson method is to be used to solve the problem. This paper deals with the numerical procedure description. The numerical results derived from the described procedure shall be published later.

  14. New Rapid Evaluation for Long-Term Behavior in Deep Geological Repository by Geotechnical Centrifuge—Part 2: Numerical Simulation of Model Tests in Isothermal Condition

    Science.gov (United States)

    Sawada, Masataka; Nishimoto, Soshi; Okada, Tetsuji

    2017-01-01

    In high-level radioactive waste disposal repositories, there are long-term complex thermal, hydraulic, and mechanical (T-H-M) phenomena that involve the generation of heat from the waste, the infiltration of ground water, and swelling of the bentonite buffer. The ability to model such coupled phenomena is of particular importance to the repository design and assessments of its safety. We have developed a T-H-M-coupled analysis program that evaluates the long-term behavior around the repository (called "near-field"). We have also conducted centrifugal model tests that model the long-term T-H-M-coupled behavior in the near-field. In this study, we conduct H-M-coupled numerical simulations of the centrifugal near-field model tests. We compare numerical results with each other and with results obtained from the centrifugal model tests. From the comparison, we deduce that: (1) in the numerical simulation, water infiltration in the rock mass was in agreement with the experimental observation. (2) The constant-stress boundary condition in the centrifugal model tests may cause a larger expansion of the rock mass than in the in situ condition, but the mechanical boundary condition did not affect the buffer behavior in the deposition hole. (3) The numerical simulation broadly reproduced the measured bentonite pressure and the overpack displacement, but did not reproduce the decreasing trend of the bentonite pressure after 100 equivalent years. This indicates the effect of the time-dependent characteristics of the surrounding rock mass. Further investigations are needed to determine the effect of initial heterogeneity in the deposition hole and the time-dependent behavior of the surrounding rock mass.

  15. Introduction to numerical analysis

    CERN Document Server

    Hildebrand, F B

    1987-01-01

    Well-known, respected introduction, updated to integrate concepts and procedures associated with computers. Computation, approximation, interpolation, numerical differentiation and integration, smoothing of data, other topics in lucid presentation. Includes 150 additional problems in this edition. Bibliography.

  16. Numerical electrokinetics.

    Science.gov (United States)

    Schmitz, R; Dünweg, B

    2012-11-21

    A new lattice method is presented in order to efficiently solve the electrokinetic equations, which describe the structure and dynamics of the charge cloud and the flow field surrounding a single charged colloidal sphere, or a fixed array of such objects. We focus on calculating the electrophoretic mobility in the limit of small driving field, and systematically linearize the equations with respect to the latter. This gives rise to several subproblems, each of which is solved by a specialized numerical algorithm. For the total problem we combine these solvers in an iterative procedure. Applying this method, we study the effect of the screening mechanism (salt screening versus counterion screening) on the electrophoretic mobility, and find a weak non-trivial dependence, as expected from scaling theory. Furthermore, we find that the orientation of the charge cloud (i.e. its dipole moment) depends on the value of the colloid charge, as a result of a competition between electrostatic and hydrodynamic effects.

  17. Interactive numerals

    Science.gov (United States)

    2017-01-01

    Although Arabic numerals (like ‘2016’ and ‘3.14’) are ubiquitous, we show that in interactive computer applications they are often misleading and surprisingly unreliable. We introduce interactive numerals as a new concept and show, like Roman numerals and Arabic numerals, interactive numerals introduce another way of using and thinking about numbers. Properly understanding interactive numerals is essential for all computer applications that involve numerical data entered by users, including finance, medicine, aviation and science. PMID:28484609

  18. Rapid synthesis of long chain fatty acid esters of steroids in ionic liquids with microwave irradiation: expedient one-pot procedure for estradiol monoesters.

    Science.gov (United States)

    Deb, Somdatta; Wähälä, Kristiina

    2010-10-01

    We report the rapid synthesis (1min) in high yield of fatty acid ester (FAE) derivatives of several steroids under microwave irradiation in an ionic liquid (IL). An expedient regioselective hydrolysis at C-3 of estradiol diesters is also reported.

  19. Cardiac Procedures and Surgeries

    Science.gov (United States)

    ... a heart is irreversibly damaged. Uses hearts from organ donation. Reason for the Procedure Recognized as a proven ... Reason for the Procedure Preferred treatment for many types of rapid heartbeats (arrhythmias) especially supraventricular tachyarrhythmias. Learn ...

  20. Calibration of 4π NaI(Tl) detectors with coincidence summing correction using new numerical procedure and ANGLE4 software

    Science.gov (United States)

    Badawi, Mohamed S.; Jovanovic, Slobodan I.; Thabet, Abouzeid A.; El-Khatib, Ahmed M.; Dlabac, Aleksandar D.; Salem, Bohaysa A.; Gouda, Mona M.; Mihaljevic, Nikola N.; Almugren, Kholud S.; Abbas, Mahmoud I.

    2017-03-01

    The 4π NaI(Tl) γ-ray detectors are consisted of the well cavity with cylindrical cross section, and the enclosing geometry of measurements with large detection angle. This leads to exceptionally high efficiency level and a significant coincidence summing effect, much more than a single cylindrical or coaxial detector especially in very low activity measurements. In the present work, the detection effective solid angle in addition to both full-energy peak and total efficiencies of well-type detectors, were mainly calculated by the new numerical simulation method (NSM) and ANGLE4 software. To obtain the coincidence summing correction factors through the previously mentioned methods, the simulation of the coincident emission of photons was modeled mathematically, based on the analytical equations and complex integrations over the radioactive volumetric sources including the self-attenuation factor. The measured full-energy peak efficiencies and correction factors were done by using 152Eu, where an exact adjustment is required for the detector efficiency curve, because neglecting the coincidence summing effect can make the results inconsistent with the whole. These phenomena, in general due to the efficiency calibration process and the coincidence summing corrections, appear jointly. The full-energy peak and the total efficiencies from the two methods typically agree with discrepancy 10%. The discrepancy between the simulation, ANGLE4 and measured full-energy peak after corrections for the coincidence summing effect was on the average, while not exceeding 14%. Therefore, this technique can be easily applied in establishing the efficiency calibration curves of well-type detectors.

  1. Rapid Attachment of Adipose Stromal Cells on Resorbable Polymeric Scaffolds Facilitates the One-Step Surgical Procedure for Cartilage and Bone Tissue Engineering Purposes

    NARCIS (Netherlands)

    Jurgens, Wouter J.; Kroeze, Robert Jan; Bank, Ruud A.; Ritt, Marco J. P. F.; Helder, Marco N.

    The stromal vascular fraction (SVF) of adipose tissue provides an abundant source of mesenchymal stem cells. For clinical application, it would be beneficial to establish treatments in which SVF is obtained, seeded onto a scaffold, and returned into the patient within a single surgical procedure. In

  2. Rapid attachment of adipose stromal cells on resorbable polymeric scaffolds facilitates the one-step surgical procedure for cartilage and bone tissue engineering purposes

    NARCIS (Netherlands)

    Jurgens, W.J.; Kroeze, R.J.; Bank, R.A.; Ritt, M.J.P.F.; Helder, M.N.

    2011-01-01

    The stromal vascular fraction (SVF) of adipose tissue provides an abundant source of mesenchymal stem cells. For clinical application, it would be beneficial to establish treatments in which SVF is obtained, seeded onto a scaffold, and returned into the patient within a single surgical procedure. In

  3. Rapid Refresh (RAP) [13 km

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Rapid Refresh (RAP) numerical weather model took the place of the Rapid Update Cycle (RUC) on May 1, 2012. Run by the National Centers for Environmental...

  4. Rapid Refresh (RAP) [20 km

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Rapid Refresh (RAP) numerical weather model took the place of the Rapid Update Cycle (RUC) on May 1, 2012. Run by the National Centers for Environmental...

  5. Studies of second phase particles in different zirconium alloys using extractive carbon replica and an electrolytic anodic dissolution procedure [rapid communication

    Science.gov (United States)

    Toffolon-Masclet, Caroline; Brachet, Jean-Christophe; Jago, Gilles

    2002-10-01

    Zirconium alloys are widely studied for applications as cladding tubes and structural components of PWR fuel assemblies. Due to their influence on some of the alloys properties (corrosion resistance, irradiation growth, …), the crystallographic structure and the chemical stoichiometry of the second phase particles (SPP) precipitated in these alloys have to be well established. The aim of this paper is to present the results obtained using two methods of SPP extractions. The first one, the extractive carbon replica method, allowed us to determine the chemical composition of SPP in different zirconium alloys: Zr-Sn-Fe-Cr (Zircaloy-4 ®), Zr-Sn-Fe-Cr-(V,Mo), Zr-Nb and Zr-Nb-Fe alloys. The second one, an anodic dissolution procedure of the matrix, is an interesting way of isolating SPP from the surrounding α-Zr matrix, giving access to a precise determination of the crystallographic structure and lattice parameters of the SPP by X-ray diffraction. This procedure was validated for Zy-4 by comparing the SPP size distribution obtained by extraction with that directly measured on a massive Zy-4 alloy (i.e. the SPP size distributions were the same for both measurements).

  6. Numerical relativity

    CERN Document Server

    Shibata, Masaru

    2016-01-01

    This book is composed of two parts: First part describes basics in numerical relativity, that is, the formulations and methods for a solution of Einstein's equation and general relativistic matter field equations. This part will be helpful for beginners of numerical relativity who would like to understand the content of numerical relativity and its background. The second part focuses on the application of numerical relativity. A wide variety of scientific numerical results are introduced focusing in particular on the merger of binary neutron stars and black holes.

  7. Numerical analysis

    CERN Document Server

    Khabaza, I M

    1960-01-01

    Numerical Analysis is an elementary introduction to numerical analysis, its applications, limitations, and pitfalls. Methods suitable for digital computers are emphasized, but some desk computations are also described. Topics covered range from the use of digital computers in numerical work to errors in computations using desk machines, finite difference methods, and numerical solution of ordinary differential equations. This book is comprised of eight chapters and begins with an overview of the importance of digital computers in numerical analysis, followed by a discussion on errors in comput

  8. Numerical Procedures for Analyzing Dynamical Processes.

    Science.gov (United States)

    1992-02-29

    the Fubini theorem .’ From this fact it is easy to see that a prevalent subset of a finite- dimensional vector space is simply a set whose complement...x,- = ,vi I - i t Douadv. Hub- bard. Milnor. Thurston. Sullivan. see jMT]. By contrast we have the following theorem . Antimonotonicity Thf rem. Each...made, then there are nondegenerate tangenci’ values ar- bitrarilv close to ,, at which contact is broken (and vice versa). The theorem follows

  9. Rapid aquatic toxicity assay using incorporation of tritiated-thymidine into sea urchin, Arbacia punctulata, embryo: evaluation of toxicant exposure procedures

    Energy Technology Data Exchange (ETDEWEB)

    Nacci, D.E.; Jackim, E.

    1985-01-01

    Toxicity of substances in seawater was measured using growth inhibition of embryonic sea urchins during a short period after fertilization. Growth of Arbacia punctulata embryos was monitored by incorporation of tritium-labeled thymidine. The paper presents a comparison of toxicant exposure procedures using the Arbacia embryo thymidine incorporation test. Toxicant exposure began before, at the time of, or after fertilization and continued for 4 h following fertilization. In addition to the eight organic chemicals tested for comparison to acute toxicity values for other species, several chemicals with embryotoxic potentials (tumor promoters and teratogens) were tested to determine differential sensitivities of exposed life-stages: unfertilized egg, fertilization, and early embryo. EC50 values for any one substance were not significantly changed by exposure modification. Toxicity values for exposures that included fertilization as well as early embryo growth were at least as sensitive as post-fertilization exposure values for all compounds tested except one. Because of technical ease and potential sensitivity, toxicant exposure that includes fertilization as well as early embryo growth (but not unfertilized egg exposure) is recommended for future testing.

  10. Mercury speciation in seafood samples by LC-ICP-MS with a rapid ultrasound-assisted extraction procedure: Application to the determination of mercury in Brazilian seafood samples.

    Science.gov (United States)

    Batista, Bruno Lemos; Rodrigues, Jairo L; de Souza, Samuel S; Oliveira Souza, Vanessa C; Barbosa, Fernando

    2011-06-15

    This paper describes a simple method for mercury speciation in seafood samples by LC-ICP-MS with a fast sample preparation procedure. Prior to analysis, mercury species were extracted from food samples with a solution containing mercaptoethanol, l-cysteine and HCl and sonication for 15min. Separation of mercury species was accomplished in less than 5min on a C8 reverse phase column with a mobile phase containing 0.05%-v/v mercaptoethanol, 0.4%m/v l-cysteine and 0.06molL(-1) ammonium acetate. The method detection limits were found to be 0.25, 0.20 and 0.1ngg(-1) for inorganic mercury, ethylmercury and methylmercury, respectively. Method accuracy is traceable to Certified Reference Materials (DOLT-3 and DORM-3) from the National Research Council Canada (NRCC). With the proposed method there is a considerable reduction of the time of sample preparation. Finally, the method was applied for the speciation of mercury in seafood samples purchased from the Brazilian market. Copyright © 2010 Elsevier Ltd. All rights reserved.

  11. Rapid Analysis Procedures for Triglycerides and Fatty Acids as Pentyl and Phenethyl Esters for the Detection of Butter Adulteration Using Chromatographic Techniques

    Directory of Open Access Journals (Sweden)

    Daniele Naviglio

    2017-01-01

    Full Text Available This paper presents the development of three methods for quality control, fraud detection, and authentication of butter fat and other oils/fats using chromatographic techniques, with one method for triglycerides and two methods for fatty acids (FAs. The procedure for the analysis of triglycerides requires only dissolution of the sample in n-hexane and gas chromatography (GC analysis using a capillary column. The second method is based on the transesterification of triglycerides as pentyl esters in a single-step reaction using sodium pentanoate in pentanol. The reaction proceeds at room temperature and is similar to the potassium hydroxide-catalysed transesterification of triglycerides with methanol and even more similar to the sodium methoxide method and sodium butanoate method. The advantage of using pentyl esters includes reducing the volatility of short-chain FAs, and substantial recoveries were obtained compared with methyl ester analysis. The third method involves the transesterification of triglycerides in fat through reaction with 2-phenylethanol in a single step; 2-phenylethanol possesses a chromophore, and the phenethyl esters formed are analysed by high-performance liquid chromatography (HPLC with UV detection.

  12. A procedure to convert total column ozone data to numerical weather prediction model initializing fields, and its validation via simulations of the 24--25 January 2000 east coast snowstorm

    Science.gov (United States)

    Durnford, Dorothy A.

    Satellites provide uniform data coverage globally. Thus, their data have the potential to reduce analysis errors in data sparse areas significantly, thereby improving numerical weather prediction (NWP) model forecasts. We describe a previously-used methodology to generate NWP model initial conditions (ICs) from satellite total column ozone data based on three principal steps: (1) convert a chemical total column ozone field to a dynamical mean potential vorticity (MPV) field via linear regression, (2) convert the 2D MPV field to a 3D potential vorticity (PV) field via vertical mapping onto average PV profiles, (3) invert the 3D PV field to obtain model-initializing height, temperature and wind fields in the mid and upper troposphere. Our contribution to the discipline has been to increase significantly the overall accuracy of the process through a substantial reworking of the details of this previous version. For instance, in recognition of the fact that total column ozone ridges tend to be less reliable than troughs, the MPV field that is converted to a 3D PV field in the second step is a synthesis of ozone-derived MPV troughs and analysis MPV ridges. We also adjust the vertical mapping procedure of the second step so that the MPV field converts to a more realistic 3D PV field; unrealistic PV features appearing strongly at upper levels and decaying with decreasing altitude are no longer generated. As a result of these and other novel procedures, the previously-described conversion procedure produces a more realistic set of model upper-level initializing fields. Using the 24-25 January 2000 east coast snowstorm as an example, we use the developed methodology to initialize the Mesoscale Compressible Community model (MC2). We find that ozone-influenced upper-level initializing fields improve the quantitative precipitation forecast for two of three (re)analyses. Furthermore, our best forecast of all utilizes ozone-influenced upper-level initializing fields. Finally

  13. Hindi Numerals.

    Science.gov (United States)

    Bright, William

    In most languages encountered by linguists, the numerals, considered as a paradigmatic set, constitute a morpho-syntactic problem of only moderate complexity. The Indo-Aryan language family of North India, however, presents a curious contrast. The relatively regular numeral system of Sanskrit, as it has developed historically into the modern…

  14. Numerical analysis

    CERN Document Server

    Rao, G Shanker

    2006-01-01

    About the Book: This book provides an introduction to Numerical Analysis for the students of Mathematics and Engineering. The book is designed in accordance with the common core syllabus of Numerical Analysis of Universities of Andhra Pradesh and also the syllabus prescribed in most of the Indian Universities. Salient features: Approximate and Numerical Solutions of Algebraic and Transcendental Equation Interpolation of Functions Numerical Differentiation and Integration and Numerical Solution of Ordinary Differential Equations The last three chapters deal with Curve Fitting, Eigen Values and Eigen Vectors of a Matrix and Regression Analysis. Each chapter is supplemented with a number of worked-out examples as well as number of problems to be solved by the students. This would help in the better understanding of the subject. Contents: Errors Solution of Algebraic and Transcendental Equations Finite Differences Interpolation with Equal Intervals Interpolation with Unequal Int...

  15. Elucidating the structure-property relationships of donor-π-acceptor dyes for dye-sensitized solar cells (DSSCs) through rapid library synthesis by a one-pot procedure.

    Science.gov (United States)

    Fuse, Shinichiro; Sugiyama, Sakae; Maitani, Masato M; Wada, Yuji; Ogomi, Yuhei; Hayase, Shuzi; Katoh, Ryuzi; Kaiho, Tatsuo; Takahashi, Takashi

    2014-08-18

    The creation of organic dyes with excellent high power conversion efficiency (PCE) is important for the further improvement of dye-sensitized solar cells. We wish to describe the rapid synthesis of a 112-membered donor-π-acceptor dye library by a one-pot procedure, evaluation of PCEs, and elucidation of structure-property relationships. No obvious correlations between ε, and the η were observed, whereas the HOMO and LUMO levels of the dyes were critical for η. The dyes with a more positive E(HOMO), and with an E(LUMO)dyes; nevertheless, that was not sufficient for identifying the best combination of donor, π, and acceptor blocks. Combinatorial synthesis and evaluation was important for identifying the best dye. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Numerical models

    Digital Repository Service at National Institute of Oceanography (India)

    Unnikrishnan, A.S.; Manoj, N.T.

    Various numerical models used to study the dynamics and horizontal distribution of salinity in Mandovi-Zuari estuaries, Goa, India is discussed in this chapter. Earlier, a one-dimensional network model was developed for representing the complex...

  17. A rapid and reliable species-specific identification of clinical and environmental isolates of Vibrio cholerae using a three-test procedure and recA polymerase chain reaction

    Directory of Open Access Journals (Sweden)

    A D Roozbehani

    2012-01-01

    Full Text Available Purpose: Vibrio cholerae, the cause of cholera, is one of the leading causes of morbidity and mortality in many developing countries. Most laboratories initially rely on biochemical tests for a presumptive identification of these strains, followed by a polymerase chain reaction (PCR-based method to confirm their identification. The aim of this study is to establish a rapid and reliable identification scheme for V. cholerae using a minimal, but highly specific number of biochemical tests and a PCR assay. Materials and Methods: We developed a species-specific PCR to identify V. cholerae, using a housekeeping gene recA, and used that to evaluate the sensitivity and specificity of 12 biochemical tests commonly used for screening and / or presumptive identification of V. cholerae in the clinical and environmental samples. Results: Here we introduced a combination of three biochemical tests, namely, sucrose fermentation, oxidase test, and growth in trypton broth containing 0% NaCl, as also the PCR of the recA gene, for rapid identification of V. cholerae isolates, with 100% sensitivity and specificity. The established method accurately identified a collection of 47 V. cholerae strains isolated from the clinical cases (n = 26 and surface waters (n = 21, while none of the 32 control strains belonging to different species were positive in this assay. Conclusion: The triple-test procedure introduced here is a simple and useful assay which can be adopted in cholera surveillance programs for efficient monitoring of V. cholerae in surface water and fecal samples.

  18. Numerical analysis

    CERN Document Server

    Brezinski, C

    2012-01-01

    Numerical analysis has witnessed many significant developments in the 20th century. This book brings together 16 papers dealing with historical developments, survey papers and papers on recent trends in selected areas of numerical analysis, such as: approximation and interpolation, solution of linear systems and eigenvalue problems, iterative methods, quadrature rules, solution of ordinary-, partial- and integral equations. The papers are reprinted from the 7-volume project of the Journal of Computational and Applied Mathematics on '/homepage/sac/cam/na2000/index.html<

  19. Numerical Relativity

    Science.gov (United States)

    Baker, John G.

    2009-01-01

    Recent advances in numerical relativity have fueled an explosion of progress in understanding the predictions of Einstein's theory of gravity, General Relativity, for the strong field dynamics, the gravitational radiation wave forms, and consequently the state of the remnant produced from the merger of compact binary objects. I will review recent results from the field, focusing on mergers of two black holes.

  20. Numerical relativity

    CERN Document Server

    Nakamura, T

    1993-01-01

    In GR13 we heard many reports on recent. progress as well as future plans of detection of gravitational waves. According to these reports (see the report of the workshop on the detection of gravitational waves by Paik in this volume), it is highly probable that the sensitivity of detectors such as laser interferometers and ultra low temperature resonant bars will reach the level of h ~ 10—21 by 1998. in this level we may expect the detection of the gravitational waves from astrophysical sources such as coalescing binary neutron stars once a year or so. Therefore the progress in numerical relativity is urgently required to predict the wave pattern and amplitude of the gravitational waves from realistic astrophysical sources. The time left for numerical relativists is only six years or so although there are so many difficulties in principle as well as in practice.

  1. Numerical methods

    OpenAIRE

    Agelet de Saracibar Bosch, Carlos; Boman, Romain; Bussetta, Philippe; Cajas García, Juan Carlos; Cervera Ruiz, Miguel; Chiumenti, Michèle; Coll Sans, Abel; Dadvand, Pooyan; Hernández Ortega, Joaquín Alberto; Houzeaux, Guillaume; Pasenau de Riera, Miguel; Ponthot, Jean Philippe

    2016-01-01

    As one of the results of an ambitious project, this handbook provides a well-structured directory of globally available software tools in the area of Integrated Computational Materials Engineering (ICME). The compilation covers models, software tools, and numerical methods allowing describing electronic, atomistic, and mesoscopic phenomena, which in their combination determine the microstructure and the properties of materials. It reaches out to simulations of component manufacture compris...

  2. A rapid one step purification procedure for murine IgD based on the specific affinity of Bandeiraea (Griffonia) simplicifolia-1 for N-linked carbohydrates on IgD.

    Science.gov (United States)

    Oppenheim, J D; Amin, A R; Thorbecke, G J

    1990-07-03

    The alpha-D-galactopyranosyl binding lectin from the seeds of Bandeiraea simplicifolia (a.k.a. Griffonia simplicifolia) termed BS-I, strongly reacts with murine IgD and with no other protein in ascites including all other classes of immunoglobulins as determined by immunoprecipitation, hemagglutination inhibition and affinity binding. Based on this finding, murine IgD could be rapidly purified directly from whole ascitic fluid by passage over affinity beads of BS-I linked to Sepharose 4B and subsequent elution by a buffer containing 0.1 M D-galactose. The sugar eluted product is 95-99% pure as determined by SDS-PAGE and represents 90-95% of the total IgD in the initial ascites by ELISA assay. Both monomeric and dimeric murine IgD may be purified by this procedure. Human IgD is unreactive with this lectin. Treatment of purified IgD with endoglycosidases that remove either O- or N-linked glycosides indicates that BS-I binds to IgD only via N-linked carbohydrate chains.

  3. Numerical analysis

    CERN Document Server

    Jacques, Ian

    1987-01-01

    This book is primarily intended for undergraduates in mathematics, the physical sciences and engineering. It introduces students to most of the techniques forming the core component of courses in numerical analysis. The text is divided into eight chapters which are largely self-contained. However, with a subject as intricately woven as mathematics, there is inevitably some interdependence between them. The level of difficulty varies and, although emphasis is firmly placed on the methods themselves rather than their analysis, we have not hesitated to include theoretical material when we consider it to be sufficiently interesting. However, it should be possible to omit those parts that do seem daunting while still being able to follow the worked examples and to tackle the exercises accompanying each section. Familiarity with the basic results of analysis and linear algebra is assumed since these are normally taught in first courses on mathematical methods. For reference purposes a list of theorems used in the t...

  4. Numerical Hydrodynamics in General Relativity

    Directory of Open Access Journals (Sweden)

    Font José A.

    2000-05-01

    Full Text Available The current status of numerical solutions for the equations of ideal general relativistic hydrodynamics is reviewed. Different formulations of the equations are presented, with special mention of conservative and hyperbolic formulations well-adapted to advanced numerical methods. A representative sample of available numerical schemes is discussed and particular emphasis is paid to solution procedures based on schemes exploiting the characteristic structure of the equations through linearized Riemann solvers. A comprehensive summary of relevant astrophysical simulations in strong gravitational fields, including gravitational collapse, accretion onto black holes and evolution of neutron stars, is also presented.

  5. Theoretical numerical analysis a functional analysis framework

    CERN Document Server

    Atkinson, Kendall

    2005-01-01

    This textbook prepares graduate students for research in numerical analysis/computational mathematics by giving to them a mathematical framework embedded in functional analysis and focused on numerical analysis. This helps the student to move rapidly into a research program. The text covers basic results of functional analysis, approximation theory, Fourier analysis and wavelets, iteration methods for nonlinear equations, finite difference methods, Sobolev spaces and weak formulations of boundary value problems, finite element methods, elliptic variational inequalities and their numerical solu

  6. Numerical Methods For Chemically Reacting Flows

    Science.gov (United States)

    Leveque, R. J.; Yee, H. C.

    1990-01-01

    Issues related to numerical stability, accuracy, and resolution discussed. Technical memorandum presents issues in numerical solution of hyperbolic conservation laws containing "stiff" (relatively large and rapidly changing) source terms. Such equations often used to represent chemically reacting flows. Usually solved by finite-difference numerical methods. Source terms generally necessitate use of small time and/or space steps to obtain sufficient resolution, especially at discontinuities, where incorrect mathematical modeling results in unphysical solutions.

  7. On the additive splitting procedures and their computer realization

    DEFF Research Database (Denmark)

    Farago, I.; Thomsen, Per Grove; Zlatev, Z.

    2008-01-01

    splitting procedures are tested by using six different numerical methods for solving differential equations. Many conclusions, which are related both to the comparison of the additive splitting procedures with the other splitting procedures and to the influence of the numerical methods for solving...... differential equations on the accuracy of the splitting procedures, are drawn....

  8. Rapid Prototyping

    Science.gov (United States)

    1999-01-01

    Javelin, a Lone Peak Engineering Inc. Company has introduced the SteamRoller(TM) System as a commercial product. The system was designed by Javelin during a Phase II NASA funded small commercial product. The purpose of the invention was to allow automated-feed of flexible ceramic tapes to the Laminated Object Manufacturing rapid prototyping equipment. The ceramic material that Javelin was working with during the Phase II project is silicon nitride. This engineered ceramic material is of interest for space-based component.

  9. Photodigitizing procedures

    Science.gov (United States)

    Kilgore, P. D.; Gottbrath, J. H.

    1984-02-01

    This report documents procedures and programs for efficiently running the Photo Digitizing System at the Naval Biodynamics Laboratory. Procedures have been tested and have been found to be effective. Any future acquisitions of programs or changes to current programs should be incorporated in these procedures. On-going research programs use high speed instrumentation cameras to record the motion of test subjects during biodynamic experiments. The films are digitized and the 3-dimensional motion is reconstructed and analyzed. Experimental research is performed to determine the effects of aircraft crashes, ship motion, vibration, aircraft ejection and parachute opening forces on the health and performance of Navy personnel.

  10. Efficacy and safety of a 4-factor prothrombin complex concentrate for rapid vitamin K antagonist reversal in Japanese patients presenting with major bleeding or requiring urgent surgical or invasive procedures: a prospective, open-label, single-arm phase 3b study.

    Science.gov (United States)

    Kushimoto, Shigeki; Fukuoka, Toshio; Kimura, Akio; Toyoda, Kazunori; Brainsky, Andres; Harman, Amy; Chung, Thomas; Yasaka, Masahiro

    2017-12-01

    Rapid vitamin K antagonist (VKA) reversal is required in patients experiencing major bleeding or requiring urgent surgery. Four-factor prothrombin complex concentrate (4F-PCC; Beriplex®/Kcentra®) was shown in two large randomized controlled, international phase 3b trials to be an effective alternative to plasma for urgent VKA reversal. In the present prospective, open-label, single-arm phase 3b trial, we evaluate the efficacy and safety of 4F-PCC in Japanese patients. Eleven patients [international normalized ratio (INR) ≥2] requiring rapid VKA reversal owing to major bleeding (n = 6) or before urgent surgical/invasive procedures (n = 5) were administered 4F-PCC dosed based on INR and weight. INR reduction (≤1.3 0.5 h postinfusion; primary endpoint) was achieved in 81.8% of patients (major bleeding, 83.3%; surgical/invasive procedures, 80.0%). Effective hemostasis (main secondary endpoint) was met in 60.0% (major bleeding) and 100% (surgical/invasive procedure) of evaluable patients. Adverse events (AEs) and serious AEs were reported in 90.9 and 45.5% of patients, respectively. Two AEs were considered treatment-related; thromboembolic events rated mild and not clinically relevant by investigators. There were no deaths, fluid overload events, or viral transmission cases. Consistent with the previous results, 4F-PCC may be an effective and well-tolerated treatment for rapid VKA reversal in Japanese patients experiencing major bleeding or requiring urgent surgical/invasive procedures.

  11. Numerical simulation by cubic-polynomial interpolation for unsteady, incompressible, viscous flow

    Science.gov (United States)

    Sugiyama, Hiromi

    1995-01-01

    A procedure for computing time-accurate solutions to the incompressible Navier-Stokes equations is presented. The procedure, designated as the CIP-ACE method, uses (1) an artificial compressibility approach to transform the equations into a hyperbolic system, (2) a fractional-step-like approach, and (3) cubic-polynomial interpolation to upwind difference the N-S equations. Two sample incompressible flow problems with known exact solutions were used to validate this CIP-ACE method. The method showed rapid convergence to a numerical solution that is reasonably compatible with the exact solutions. Furthermore, it can be extended to solve the three-dimensional, incompressible N-S equations in generalized coordinates, making it an attractive alternative to more established numerical methods.

  12. Electric analogue for the dynamics of decompression sickness bubbles: Numerical results

    Science.gov (United States)

    Zueco, Joaquín; Hernández-González, A.

    2010-01-01

    Since the development of the first decompression tables in 1908 by Boycott, Damant and Haldane, considerable research and effort have been expended in the development of safer and more rapid decompression procedures and tables. The models for gas exchange have been principally empirical and provide "safe" decompression only over a limited range of depth and bottom times. In this work a numerical method based on an electrical analogy is used to solve the system of equations simulating the growth and decay dynamics of decompression bubbles. The numerical procedure employed, which satisfies the conservation law for the flux variable and the uniqueness law for voltages, also permits the direct visualisation of the evolution of the local and/or integrated transport variables at any point or section of the medium.

  13. Numerical Hydrodynamics in General Relativity

    Directory of Open Access Journals (Sweden)

    Font José A.

    2003-01-01

    Full Text Available The current status of numerical solutions for the equations of ideal general relativistic hydrodynamics is reviewed. With respect to an earlier version of the article, the present update provides additional information on numerical schemes, and extends the discussion of astrophysical simulations in general relativistic hydrodynamics. Different formulations of the equations are presented, with special mention of conservative and hyperbolic formulations well-adapted to advanced numerical methods. A large sample of available numerical schemes is discussed, paying particular attention to solution procedures based on schemes exploiting the characteristic structure of the equations through linearized Riemann solvers. A comprehensive summary of astrophysical simulations in strong gravitational fields is presented. These include gravitational collapse, accretion onto black holes, and hydrodynamical evolutions of neutron stars. The material contained in these sections highlights the numerical challenges of various representative simulations. It also follows, to some extent, the chronological development of the field, concerning advances on the formulation of the gravitational field and hydrodynamic equations and the numerical methodology designed to solve them.

  14. Rapid chemical separations

    CERN Document Server

    Trautmann, N

    1976-01-01

    A survey is given on the progress of fast chemical separation procedures during the last few years. Fast, discontinuous separation techniques are illustrated by a procedure for niobium. The use of such techniques for the chemical characterization of the heaviest known elements is described. Other rapid separation methods from aqueous solutions are summarized. The application of the high speed liquid chromatography to the separation of chemically similar elements is outlined. The use of the gas jet recoil transport method for nuclear reaction products and its combination with a continuous solvent extraction technique and with a thermochromatographic separation is presented. Different separation methods in the gas phase are briefly discussed and the attachment of a thermochromatographic technique to an on-line mass separator is shown. (45 refs).

  15. Excel spreadsheet in teaching numerical methods

    Science.gov (United States)

    Djamila, Harimi

    2017-09-01

    One of the important objectives in teaching numerical methods for undergraduates’ students is to bring into the comprehension of numerical methods algorithms. Although, manual calculation is important in understanding the procedure, it is time consuming and prone to error. This is specifically the case when considering the iteration procedure used in many numerical methods. Currently, many commercial programs are useful in teaching numerical methods such as Matlab, Maple, and Mathematica. These are usually not user-friendly by the uninitiated. Excel spreadsheet offers an initial level of programming, which it can be used either in or off campus. The students will not be distracted with writing codes. It must be emphasized that general commercial software is required to be introduced later to more elaborated questions. This article aims to report on a teaching numerical methods strategy for undergraduates engineering programs. It is directed to students, lecturers and researchers in engineering field.

  16. Rapid Airplane Parametric Input Design (RAPID)

    Science.gov (United States)

    Smith, Robert E.

    1995-01-01

    ADIFOR to the grid generation program. The output of ADIFOR is a new source code containing the old code plus expressions for derivatives of specified dependent variables (grid coordinates) with respect to specified independent variables (design parameters). The RAPID methodology and software provide a means of rapidly defining numerical prototypes, grids, and grid sensitivity of a class of airplane configurations. This technology and software is highly useful for CFD research for preliminary design and optimization processes.

  17. Ross procedure

    OpenAIRE

    Sievers, H.H.

    2012-01-01

    Introduction In 1967 Donald Ross introduced the subcoronary Ross procedure consisting of transplantation of the autologous pulmonary valve into aortic position. We describe our 15-year experience in Ross procedures. Methods 576 subcoronary operations have been performed (436 male and 140 female patients); the mean age was 45?11.9 years. (range, 13 to 70 years). The mean follow-up was 7?4.2 years (range, 0 to 16 years). There were 4597 patient years at follow-up with a clinical completeness of...

  18. Numerical Optimization in Microfluidics

    DEFF Research Database (Denmark)

    Jensen, Kristian Ejlebjærg

    2017-01-01

    Numerical modelling can illuminate the working mechanism and limitations of microfluidic devices. Such insights are useful in their own right, but one can take advantage of numerical modelling in a systematic way using numerical optimization. In this chapter we will discuss when and how numerical...

  19. Universal Numeric Segmented Display

    OpenAIRE

    Azad, Md. Abul Kalam; Sharmeen, Rezwana; S. M. Kamruzzaman

    2010-01-01

    Segmentation display plays a vital role to display numerals. But in today's world matrix display is also used in displaying numerals. Because numerals has lots of curve edges which is better supported by matrix display. But as matrix display is costly and complex to implement and also needs more memory, segment display is generally used to display numerals. But as there is yet no proposed compact display architecture to display multiple language numerals at a time, this paper proposes uniform...

  20. Fair Procedures.

    Science.gov (United States)

    Eaneman, Paulette S.; And Others

    These materials are part of the Project Benchmark series designed to teach secondary students about our legal concepts and systems. This unit focuses on individual rights and fair procedures under the law. The materials outline the Bill of Rights, due process guarantees, the right to a fair hearing, fair and unfair trials, search and seizure laws,…

  1. (TIPSS) procedure

    African Journals Online (AJOL)

    Enrique

    mental animals.7. In 1982, Colapinto and co-workers described the creation of percutaneous intrahepatic shunts in 6 human subjects.8 A tract was dilated through the ... REVIEW ARTICLE. 4. SA JOURNAL OF RADIOLOGY • October 2004. The transjugular intrahepatic porto- systemic shunt. (TIPSS) procedure — a review.

  2. Peritonectomy procedures.

    Science.gov (United States)

    Sugarbaker, P H

    1995-01-01

    OBJECTIVE: New surgical procedures designed to assist in the treatment of peritoneal surface malignancy were sought. BACKGROUND: Decisions regarding the treatment of cancer depend on the anatomic location of the malignancy and the biologic aggressiveness of the disease. Some patients may have isolated intra-abdominal seeding of malignancy of limited extent or of low biologic grade. In the past, these clinical situations have been regarded as lethal. METHODS: The cytoreductive approach may require six peritonectomy procedures to resect or strip cancer from all intra-abdominal surfaces. RESULTS: These are greater omentectomy-splenectomy; left upper quadrant peritonectomy; right upper quadrant peritonectomy; lesser omentectomy-cholecystectomy with stripping of the omental bursa; pelvic peritonectomy with sleeve resection of the sigmoid colon; and antrectomy. CONCLUSIONS: Peritonectomy procedures and preparation of the abdomen for early postoperative intraperitoneal chemotherapy were described. The author has used the cytoreductive approach to achieve long-term, disease-free survival in selected patients with peritoneal carcinomatosis, peritoneal sarcomatosis or mesothelioma. Images Figure 2. Figure 3. Figure 4. Figure 5. Figure 6. Figure 7. Figure 8. Figure 9. Figure 10. Figure 11. Figure 12. Figure 13. PMID:7826158

  3. The Application Trends of Rapid Prototyping Manufacturing

    Directory of Open Access Journals (Sweden)

    Qiu Xiao Lin

    2016-01-01

    characteristics of laser stero lithography (LSL selective laser sintering (SLS, three-dimensional printing (DP, fused deposition modeling (FDM, computer numerical control (CNC and other rapid prototyping technologies. After discussed these five rapid prototyping technology materials, we presented the hotspot and direction of rapid prototyping technology and look forward to the development of its technique, the expansion of its field and the progress of its academic ideology.

  4. Fluid Dynamics Theory, Computation, and Numerical Simulation

    CERN Document Server

    Pozrikidis, Constantine

    2009-01-01

    Fluid Dynamics: Theory, Computation, and Numerical Simulation is the only available book that extends the classical field of fluid dynamics into the realm of scientific computing in a way that is both comprehensive and accessible to the beginner. The theory of fluid dynamics, and the implementation of solution procedures into numerical algorithms, are discussed hand-in-hand and with reference to computer programming. This book is an accessible introduction to theoretical and computational fluid dynamics (CFD), written from a modern perspective that unifies theory and numerical practice. There are several additions and subject expansions in the Second Edition of Fluid Dynamics, including new Matlab and FORTRAN codes. Two distinguishing features of the discourse are: solution procedures and algorithms are developed immediately after problem formulations are presented, and numerical methods are introduced on a need-to-know basis and in increasing order of difficulty. Matlab codes are presented and discussed for ...

  5. Fluid dynamics theory, computation, and numerical simulation

    CERN Document Server

    Pozrikidis, C

    2001-01-01

    Fluid Dynamics Theory, Computation, and Numerical Simulation is the only available book that extends the classical field of fluid dynamics into the realm of scientific computing in a way that is both comprehensive and accessible to the beginner The theory of fluid dynamics, and the implementation of solution procedures into numerical algorithms, are discussed hand-in-hand and with reference to computer programming This book is an accessible introduction to theoretical and computational fluid dynamics (CFD), written from a modern perspective that unifies theory and numerical practice There are several additions and subject expansions in the Second Edition of Fluid Dynamics, including new Matlab and FORTRAN codes Two distinguishing features of the discourse are solution procedures and algorithms are developed immediately after problem formulations are presented, and numerical methods are introduced on a need-to-know basis and in increasing order of difficulty Matlab codes are presented and discussed for a broad...

  6. Numerical Evaluation of 2D Ground States

    Directory of Open Access Journals (Sweden)

    Kolkovska Natalia

    2016-01-01

    The efficiency of this procedure is demonstrated in the 1D case, where the maximal difference between the exact and numerical solution is ≈ 10–11 for a discretization step 0:00025. As a major application, we evaluate numerically the critical energy constant. This constant is defined as a functional of the ground state and is used in the study of the 2D Boussinesq equations.

  7. Numerical model of thyroid counter

    Directory of Open Access Journals (Sweden)

    Szuchta Maciej

    2016-03-01

    Full Text Available The aim of this study was to develop a numerical model of spectrometric thyroid counter, which is used for the measurements of internal contamination by in vivo method. The modeled detector is used for a routine internal exposure monitoring procedure in the Radiation Protection Measurements Laboratory of National Centre for Nuclear Research (NCBJ. This procedure may also be used for monitoring of occupationally exposed nuclear medicine personnel. The developed model was prepared using Monte Carlo code FLUKA 2011 ver. 2b.6 Apr-14 and FLAIR ver. 1.2-5 interface. It contains a scintillation NaI(Tl detector, the collimator and the thyroid water phantom with a reference source of iodine 131I. The geometry of the model was designed and a gamma energy spectrum of iodine 131I deposited in the detector was calculated.

  8. On Some Numerical Properties of ARMA Parameter Estimation Procedures.

    Science.gov (United States)

    1981-07-01

    respectively for t < K. of this algorithm to ARliA models ran be made to fr _K obtain thte ie(t) nd n2 - Thum s ne dIf Y(-) is a purely nondeterministic...attempt to find Y(t+hlt) and 02h that if Y(.) - ARMA(p, q, a, B, o2), and one forms the An (nxn) symmetric matrix An Ls positive defi- p mite if and only...Ansley (1979) makes this DA n is a diagonal matrix with positive diagonal same transformation of Y(.) to X(.) to get theA~ne(t) and 02necessary to

  9. Review of numerical procedures for computational surface thermochemistry

    Science.gov (United States)

    Milos, Frank S.; Rasky, Daniel J.

    1994-01-01

    Models and equations for surface thermochemistry and near-surface thermophysics of aerodynamically heated thermal protection materials are reviewed, with particular emphasis on computational boundary conditions for surface mass and energy transfer. The surface energy and mass balances, coupled with an appropriate ablation or surface catalysis model, provide complete thermochemical boundary conditions for a true multidisciplinary solution of the fully coupled fluid-dynamics/solid mechanics problem. Practical approximate solutions can be obtained by using a detailed model with full thermophysics for either the solid or fluid phase and a semianalytic method for the other half of the problem. A significant increase in the state-of-the-art in aerothermal computational fluid dynamics is possible by uniting computational fluid dynamic (CFD) methodology with surface thermochemistry boundary conditions and the heat-balance-integral method.

  10. Numerical procedures for three-dimensional computational surface thermochemistry

    Science.gov (United States)

    Milos, Frank S.; Rasky, Daniel J.

    1992-01-01

    Models and equations for surface thermochemistry and near-surface thermophysics of aerodynamically-heated thermal protection materials are reviewed, with particular emphasis on computational boundary conditions for surface mass and energy transfer. The surface energy and mass balances, coupled with an appropriate ablation or surface catalysis model, provide complete thermochemical boundary conditions for a true multidisciplinary solution of the fully coupled fluid-dynamics/solid mechanics problem. Practical approximate solutions can be obtained by using a detailed model with full thermophysics for either the solid or fluid phase amd a semianalytic method for the other half of the problem. A significant increase in the state-of-the-art in aerothermal computational fluid dynamics is possible by uniting CFD methodology with surface thermochemistry boundary conditions and the heat-balance-integral method.

  11. Ross procedure.

    Science.gov (United States)

    Sievers, H H

    2012-01-01

    In 1967 Donald Ross introduced the subcoronary Ross procedure consisting of transplantation of the autologous pulmonary valve into aortic position. We describe our 15-year experience in Ross procedures. 576 subcoronary operations have been performed (436 male and 140 female patients); the mean age was 45±11.9 years. (range, 13 to 70 years). The mean follow-up was 7±4.2 years (range, 0 to 16 years). There were 4597 patient years at follow-up with a clinical completeness of 95% and echo completeness of 91%. There were two operative deaths (0.3%) and 31 patients with reoperation. The survival is similar to that of the normal population and the freedom from allo- and autograft reoperation is 87% at 15 years. Autograft regurgitation at last examination was grade 0 in 40%, trace in 54%, grade I in 19%, grade II in 4% and grade III in 0.4%; the pressure gradient was smaller than 5 mmHg in 57% and between 5 and 10 mmHg in 24%. Only 6% had a transvalvular pressure gradient of more than 10 mmHg. After 15 years of experience it can be concluded that the subcoronary technique provides near normal survival in adult patients, with excellent hemodynamics and acceptable rate of reoperations.

  12. Procedural knowledge

    Science.gov (United States)

    Georgeff, Michael P.; Lansky, Amy L.

    1986-01-01

    Much of commonsense knowledge about the real world is in the form of procedures or sequences of actions for achieving particular goals. In this paper, a formalism is presented for representing such knowledge using the notion of process. A declarative semantics for the representation is given, which allows a user to state facts about the effects of doing things in the problem domain of interest. An operational semantics is also provided, which shows how this knowledge can be used to achieve particular goals or to form intentions regarding their achievement. Given both semantics, the formalism additionally serves as an executable specification language suitable for constructing complex systems. A system based on this formalism is described, and examples involving control of an autonomous robot and fault diagnosis for NASA's Space Shuttle are provided.

  13. Procedural knowledge

    Energy Technology Data Exchange (ETDEWEB)

    Georgeff, M.P.; Lansky, A.L.

    1986-10-01

    Much of commonsense knowledge about the real world is in the form of procedures or sequences of actions for achieving particular goals. In this paper, a formalism is presented for representing such knowledge using the notion of process. A declarative semantics for the representation is given, which allows a user to state facts about the effects of doing things in the problem domain of interest. An operational semantics is also provided, which shows how this knowledge can be used to achieve particular goals or to form intentions regarding their achievement. Given both semantics, our formalism additionally serves as an executable specification language suitable for constructing complex systems. A system based on this formalism is described, and examples involving control of an autonomous robot and fault diagnosis for NASA's space shuttle are provided.

  14. Mathematical and Numerical Modeling in Maritime Geomechanics

    Directory of Open Access Journals (Sweden)

    Miguel Martín Stickle

    2012-04-01

    Full Text Available A theoretical and numerical framework to model the foundation of marine offshore structures is presented. The theoretical model is composed by a system of partial differential equations describing coupling between seabed solid skeleton and pore fluids (water, air, oil,... combined with a system of ordinary differential equations describing the specific constitutive relation of the seabed soil skeleton. Once the theoretical model is described, the finite element numerical procedure to achieve an approximate solution of the overning equations is outlined. In order to validate the proposed theoretical and numerical framework the seaward tilt mechanism induced by the action of breaking waves over a vertical breakwater is numerically reproduced. The results numerically attained are in agreement with the main conclusions drawn from the literature associated with this failure mechanism.

  15. Inhaled methoxyflurane for pain and anxiety relief during burn wound care procedures: an Australian case series.

    Science.gov (United States)

    Wasiak, Jason; Mahar, Patrick D; Paul, Eldho; Menezes, Hana; Spinks, Anneliese B; Cleland, Heather

    2014-02-01

    Pain is a common and significant feature of burn injury. The use of intravenous opioids forms the mainstay of procedural burn pain management, but in an outpatient setting, the demand for novel agents that do not require parenteral access, are easy to administer and have a rapid onset are urgently needed. One such agent is the inhaled anaesthetic agent, methoxyflurane (MF). The aim of this study was to conduct a pilot investigation into the clinical effectiveness of MF inhaler on pain and anxiety scores in patients undergoing burn wound care procedures in an outpatient setting. A prospective case series involved recruiting patients undergoing a burn wound care procedure in an ambulatory burn care setting. Pain and anxiety were assessed using numerical rating scales. Overall, median numerical pain rating score was significantly higher post-dressing [pre-dressing: 2; interquartile range (IQR): 1-3 versus post-dressing: 3; IQR 1·5-4; P = 0·01], whereas median numerical anxiety score significantly reduced following the dressing (pre-dressing: 5; IQR 4-7 versus post-dressing: 2; IQR 1-2; P burn care procedures in the ambulatory care setting. However, there is an urgent need for larger case series and randomised controlled trials to determine its overall clinical effectiveness. © 2012 The Authors. International Wound Journal © 2012 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

  16. A numerical library in Java for scientists and engineers

    CERN Document Server

    Lau, Hang T

    2003-01-01

    At last researchers have an inexpensive library of Java-based numeric procedures for use in scientific computation. The first and only book of its kind, A Numeric Library in Java for Scientists and Engineers is a translation into Java of the library NUMAL (NUMerical procedures in ALgol 60). This groundbreaking text presents procedural descriptions for linear algebra, ordinary and partial differential equations, optimization, parameter estimation, mathematical physics, and other tools that are indispensable to any dynamic research group. The book offers test programs that allow researchers to execute the examples provided; users are free to construct their own tests and apply the numeric procedures to them in order to observe a successful computation or simulate failure. The entry for each procedure is logically presented, with name, usage parameters, and Java code included. This handbook serves as a powerful research tool, enabling the performance of critical computations in Java. It stands as a cost-effi...

  17. Supertasks and Numeral Systems

    OpenAIRE

    Rizza, Davide

    2016-01-01

    Physical supertasks are completed, infinite sequences of events or interactions that occur within a finite amount of time. Examples thereof have been constructed to show that infinite physical systems may violate conservation laws. It is shown in this paper that this conclusion may be critically sensitive to a selection of numeral system. Weaker numeral systems generate physical reports whose inaccuracy simulates the violation of a conservation law. Stronger numeral systems can confirm this e...

  18. Vascular Access Procedures

    Science.gov (United States)

    ... News Physician Resources Professions Site Index A-Z Vascular Access Procedures A vascular access procedure inserts a flexible, ... the limitations of Vascular Access Procedures? What are Vascular Access Procedures? A vascular access procedure involves the insertion ...

  19. Supertasks and numeral systems

    Science.gov (United States)

    Rizza, Davide

    2016-10-01

    Physical supertasks are completed, infinite sequences of events or interactions that occur within a finite amount of time. Examples thereof have been constructed to show that infinite physical systems may violate conservation laws. It is shown in this paper that this conclusion may be critically sensitive to a selection of numeral system. Weaker numeral systems generate physical reports whose inaccuracy simulates the violation of a conservation law. Stronger numeral systems can confirm this effect by allowing a direct computation of the quantities conserved. The supertasks presented in [2], [4] are used to illustrate this phenomenon from the point of view of the new numeral system introduced in [6].

  20. Numerical methods using Matlab

    CERN Document Server

    Lindfield, George

    2012-01-01

    Numerical Methods using MATLAB, 3e, is an extensive reference offering hundreds of useful and important numerical algorithms that can be implemented into MATLAB for a graphical interpretation to help researchers analyze a particular outcome. Many worked examples are given together with exercises and solutions to illustrate how numerical methods can be used to study problems that have applications in the biosciences, chaos, optimization, engineering and science across the board. Numerical Methods using MATLAB, 3e, is an extensive reference offering hundreds of use

  1. Numerical pole assignment by eigenvalue Jacobian inversion

    Science.gov (United States)

    Sevaston, George E.

    1986-01-01

    A numerical procedure for solving the linear pole placement problem is developed which operates by the inversion of an analytically determined eigenvalue Jacobian matrix. Attention is given to convergence characteristics and pathological situations. It is not concluded that the algorithm developed is suitable for computer-aided control system design with particular reference to the scan platform pointing control system for the Galileo spacecraft.

  2. Rapid prototyping--when virtual meets reality.

    Science.gov (United States)

    Beguma, Zubeda; Chhedat, Pratik

    2014-01-01

    Rapid prototyping (RP) describes the customized production of solid models using 3D computer data. Over the past decade, advances in RP have continued to evolve, resulting in the development of new techniques that have been applied to the fabrication of various prostheses. RP fabrication technologies include stereolithography (SLA), fused deposition modeling (FDM), computer numerical controlled (CNC) milling, and, more recently, selective laser sintering (SLS). The applications of RP techniques for dentistry include wax pattern fabrication for dental prostheses, dental (facial) prostheses mold (shell) fabrication, and removable dental prostheses framework fabrication. In the past, a physical plastic shape of the removable partial denture (RPD) framework was produced using an RP machine, and then used as a sacrificial pattern. Yet with the advent of the selective laser melting (SLM) technique, RPD metal frameworks can be directly fabricated, thereby omitting the casting stage. This new approach can also generate the wax pattern for facial prostheses directly, thereby reducing labor-intensive laboratory procedures. Many people stand to benefit from these new RP techniques for producing various forms of dental prostheses, which in the near future could transform traditional prosthodontic practices.

  3. Comparison of transition-matrix sampling procedures

    DEFF Research Database (Denmark)

    Yevick, D.; Reimer, M.; Tromborg, Bjarne

    2009-01-01

    We compare the accuracy of the multicanonical procedure with that of transition-matrix models of static and dynamic communication system properties incorporating different acceptance rules. We find that for appropriate ranges of the underlying numerical parameters, algorithmically simple yet high...... accurate procedures can be employed in place of the standard multicanonical sampling algorithm....

  4. Action principle for Numerical Relativity evolution systems

    CERN Document Server

    Bona, C; Palenzuela, C

    2010-01-01

    A Lagrangian density is provided, that allows to recover the Z4 evolution system from an action principle. The resulting system is then strongly hyperbolic when supplemented by gauge conditions like '1+log' or 'freezing shift', suitable for numerical evolution. The physical constraint $Z_\\mu = 0$ can be imposed just on the initial data. The corresponding Hamiltonian and canonical equations are also provided. This opens the door to analogous results for other numerical-relativity formalisms, like BSSN, that can be derived from Z4 by a symmetry-breaking procedure. The harmonic formulation can be easily recovered by a slight modification of the procedure. This provides a mechanism for deriving both the field evolution equations and the gauge conditions from the action principle, with a view on using simplectic integrators for a constraint-preserving numerical evolution.

  5. Numerical Simulation of Spray Atomization in Supersonic Flows

    Science.gov (United States)

    Wang, Jiangfeng; Liu, Chen; Wu, Yizhao

    With the rapid development of the air-breathing hypersonic vehicle design, an accurate description of the combustion properties becomes more and more important, where one of the key techniques is the procedure of the liquid fuel mixing, atomizing and burning coupled with the supersonic crossflow in the combustion chamber. The movement and distribution of the liquid fuel droplets in the combustion chamber will influence greatly the combustion properties, as well as the propulsion performance of the ramjet/scramjet engine. In this paper, numerical simulation methods on unstructured hybrid meshes were carried out for liquid spray atomization in supersonic crossflows. The Kelvin-Helmholtz/Rayleigh-Taylor hybrid model was used to simulate the breakup process of the liquid spray in a supersonic crossflow with Mach number 1.94. Various spray properties, including spray penetration height, droplet size distribution, were quantitatively compared with experimental results. In addition, numerical results of the complex shock wave structure induced by the presence of liquid spray were illustrated and discussed.

  6. Numerical Modelling of Streams

    DEFF Research Database (Denmark)

    Vestergaard, Kristian

    In recent years there has been a sharp increase in the use of numerical water quality models. Numeric water quality modeling can be divided into three steps: Hydrodynamic modeling for the determination of stream flow and water levels. Modelling of transport and dispersion of a conservative dissol...... dissolved substance. Modeling of chemical and biological turnover of substances....

  7. Numerical Verification of Industrial Numerical Codes

    Directory of Open Access Journals (Sweden)

    Montan Sethy

    2012-04-01

    Full Text Available Several approximations occur during a numerical simulation: physical effects mapy be discarded, continuous functions replaced by discretized ones and real numbers replaced by finite-precision representations. The use of the floating point arithmetic generates round-off errors at each arithmetical expression and some mathematical properties are lost. The aim of the numerical verification activity at EDF R&D is to study the effect of the round-off error propagation on the results of a numerical simulation. It is indeed crucial to perform a numerical verification of industrial codes such as developped at EDF R&D even more for code running in HPC environments. This paper presents some recent studies around the numerical verification at EDF R&D. Le résultat d’un code de simulation numérique subit plusieurs approximations effectuées lors de la modélisation mathématique du problème physique, de la discrétisation du modèle mathématique et de la résolution numérique en arithmétique flottante. L’utilisation de l’arithmétique flottante génère en effet des erreurs d’arrondi lors de chaque opération flottante et des propriétés mathématiques sont perdues. Il existe à EDF R&D une activité transverse de vérification numérique consistant à étudier l’effet de la propagation des erreurs d’arrondi sur les résultats des simulations. Il est en effet important de vérifier numériquement des codes industriels et ce d’autant plus s’ils sont éxécutés dans environnements de calcul haute performance. Ce papier présente des études récentes autour de la vérification numérique à EDF R&D.

  8. Numerical Transducer Modeling

    DEFF Research Database (Denmark)

    Henriquez, Vicente Cutanda

    This thesis describes the development of a numerical model of the propagation of sound waves in fluids with viscous and thermal losses, with application to the simulation of acoustic transducers, in particular condenser microphones for measurement. The theoretical basis is presented, numerical...... with very close surfaces, as found in condenser microphones, where the membrane has a backplate very close behind. This improvement could be useful for many other problems where the BEM is applied. The numerical implementation that includes both viscous and thermal effects is then worked out. Some numerical...... that are allowable in this case: linear variations, absence of flow, harmonic time variation, thermodynamical equilibrium and physical dimensions much larger than the molecular mean free path. A formulation of the BEM is also developed with an improvement designed to cope with the numerical difficulty associated...

  9. Grid - a fast threshold tracking procedure

    DEFF Research Database (Denmark)

    Fereczkowski, Michal; Dau, Torsten; MacDonald, Ewen

    2016-01-01

    A new procedure, called “grid”, is evaluated that allows rapid acquisition of threshold curves for psychophysics and, in particular, psychoacoustic, experiments. In this method, the parameterresponse space is sampled in two dimensions within a single run. This allows the procedure to focus more e...

  10. A Parent-Oriented Approach to Rapid Toilet Training

    Science.gov (United States)

    Doan, Dai; Toussaint, Karen A.

    2016-01-01

    The current evaluation assessed the effectiveness of a rapid toilet training procedure for three young males with autism. The evaluation extended the research on rapid toilet training procedures by assessing parents' preference to include two common toilet training components, a urine alarm and positive practice. In addition, we assessed child…

  11. Numerical distance protection

    CERN Document Server

    Ziegler, Gerhard

    2011-01-01

    Distance protection provides the basis for network protection in transmission systems and meshed distribution systems. This book covers the fundamentals of distance protection and the special features of numerical technology. The emphasis is placed on the application of numerical distance relays in distribution and transmission systems.This book is aimed at students and engineers who wish to familiarise themselves with the subject of power system protection, as well as the experienced user, entering the area of numerical distance protection. Furthermore it serves as a reference guide for s

  12. Numerical problems in physics

    CERN Document Server

    Singh, Devraj

    2015-01-01

    Numerical Problems in Physics, Volume 1 is intended to serve the need of the students pursuing graduate and post graduate courses in universities with Physics and Materials Science as subject including those appearing in engineering, medical, and civil services entrance examinations. KEY FEATURES: * 29 chapters on Optics, Wave & Oscillations, Electromagnetic Field Theory, Solid State Physics & Modern Physics * 540 solved numerical problems of various universities and ompetitive examinations * 523 multiple choice questions for quick and clear understanding of subject matter * 567 unsolved numerical problems for grasping concepts of the various topic in Physics * 49 Figures for understanding problems and concept

  13. Introductory numerical analysis

    CERN Document Server

    Pettofrezzo, Anthony J

    2006-01-01

    Written for undergraduates who require a familiarity with the principles behind numerical analysis, this classical treatment encompasses finite differences, least squares theory, and harmonic analysis. Over 70 examples and 280 exercises. 1967 edition.

  14. Exploring Mayan Numerals

    Science.gov (United States)

    Farmer, Jeff D.; Powers, Robert A.

    2005-01-01

    This article describes an exploration activity involving Mayan numerals, which can be adapted by teachers at various levels to help students better understand the concept of place value and appreciate contributions to mathematics made by an indigenous Central American culture.

  15. Numerical computations with GPUs

    CERN Document Server

    Kindratenko, Volodymyr

    2014-01-01

    This book brings together research on numerical methods adapted for Graphics Processing Units (GPUs). It explains recent efforts to adapt classic numerical methods, including solution of linear equations and FFT, for massively parallel GPU architectures. This volume consolidates recent research and adaptations, covering widely used methods that are at the core of many scientific and engineering computations. Each chapter is written by authors working on a specific group of methods; these leading experts provide mathematical background, parallel algorithms and implementation details leading to

  16. Numerical transducer modelling

    DEFF Research Database (Denmark)

    Cutanda, Vicente

    1999-01-01

    Numerical modelling is of importance for the design, improvement and study of acoustic transducers such as microphones and accelerometers. Techniques like the boundary element method and the finite element method are the most common supplement to the traditional empirical and analytical approaches...... errors and instabilities in the computations of numerical solutions. An investigation to deal with this narrow-gap problem has been carried out....

  17. Efficient numerical modelling of the emittance evolution of beams with finite energy spread in plasma wakefield accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Mehrling, T.J., E-mail: timon.mehrling@desy.de [Deutsches Elektronen-Synchrotron DESY, 22607 Hamburg (Germany); Robson, R.E. [Centre for Quantum Dynamics, School of Natural Sciences, Griffith University, Brisbane (Australia); Erbe, J-H.; Osterhoff, J. [Deutsches Elektronen-Synchrotron DESY, 22607 Hamburg (Germany)

    2016-09-01

    This paper introduces a semi-analytic numerical approach (SANA) for the rapid computation of the transverse emittance of beams with finite energy spread in plasma wakefield accelerators in the blowout regime. The SANA method is used to model the beam emittance evolution when injected into and extracted from realistic plasma profiles. Results are compared to particle-in-cell simulations, establishing the accuracy and efficiency of the procedure. In addition, it is demonstrated that the tapering of vacuum-to-plasma and plasma-to-vacuum transitions is a viable method for the mitigation of emittance growth of beams during their injection and extraction from and into plasma cells.

  18. Hot-blade cutting of EPS foam for double-curved surfaces—numerical simulation and experiments

    DEFF Research Database (Denmark)

    Petkov, Kiril P.; Hattel, Jesper Henri

    2017-01-01

    In the present paper, experimental and numerical studies of a newly developed process of Hot-Blade Cutting used for free forming of double-curved surfaces and cost effective rapid prototyping of expanded polystyrene foam is carried out. The experimental part of the study falls in two parts......-Blade Cutting similar to the one previously proposed by Petkov and Hattel (Int J Machine Tools Manuf 107:50–59 2016) for Hot-Wire Cutting of Polystyrene foam is used to simulate the process and describe the effects taking place within the hot-blade during different cutting procedures. The obtained results...

  19. Frontiers in Numerical Relativity

    Science.gov (United States)

    Evans, Charles R.; Finn, Lee S.; Hobill, David W.

    2011-06-01

    Preface; Participants; Introduction; 1. Supercomputing and numerical relativity: a look at the past, present and future David W. Hobill and Larry L. Smarr; 2. Computational relativity in two and three dimensions Stuart L. Shapiro and Saul A. Teukolsky; 3. Slowly moving maximally charged black holes Robert C. Ferrell and Douglas M. Eardley; 4. Kepler's third law in general relativity Steven Detweiler; 5. Black hole spacetimes: testing numerical relativity David H. Bernstein, David W. Hobill and Larry L. Smarr; 6. Three dimensional initial data of numerical relativity Ken-ichi Oohara and Takashi Nakamura; 7. Initial data for collisions of black holes and other gravitational miscellany James W. York, Jr.; 8. Analytic-numerical matching for gravitational waveform extraction Andrew M. Abrahams; 9. Supernovae, gravitational radiation and the quadrupole formula L. S. Finn; 10. Gravitational radiation from perturbations of stellar core collapse models Edward Seidel and Thomas Moore; 11. General relativistic implicit radiation hydrodynamics in polar sliced space-time Paul J. Schinder; 12. General relativistic radiation hydrodynamics in spherically symmetric spacetimes A. Mezzacappa and R. A. Matzner; 13. Constraint preserving transport for magnetohydrodynamics John F. Hawley and Charles R. Evans; 14. Enforcing the momentum constraints during axisymmetric spacelike simulations Charles R. Evans; 15. Experiences with an adaptive mesh refinement algorithm in numerical relativity Matthew W. Choptuik; 16. The multigrid technique Gregory B. Cook; 17. Finite element methods in numerical relativity P. J. Mann; 18. Pseudo-spectral methods applied to gravitational collapse Silvano Bonazzola and Jean-Alain Marck; 19. Methods in 3D numerical relativity Takashi Nakamura and Ken-ichi Oohara; 20. Nonaxisymmetric rotating gravitational collapse and gravitational radiation Richard F. Stark; 21. Nonaxisymmetric neutron star collisions: initial results using smooth particle hydrodynamics

  20. Masonry constructions mechanical models and numerical applications

    CERN Document Server

    Lucchesi, Massimiliano; Padovani, Cristina

    2008-01-01

    Numerical methods for the structural analysis of masonry constructions can be of great value in assessing the safety of artistically important masonry buildings and optimizing potential operations of maintenance and strengthening in terms of their cost-effectiveness, architectural impact and static effectiveness. This monograph firstly provides a detailed description of the constitutive equation of masonry-like materials, clearly setting out its most important features. It then goes on to provide a numerical procedure to solve the equilibrium problem of masonry solids. A large portion of the w

  1. Numerical analysis of choked converging nozzle flows with surface ...

    Indian Academy of Sciences (India)

    the structural, compressible fluid, non-adiabatic & frictional flow properties (ξ) within the numerical model, the .... Figure 2. Flowchart of the numerical solution procedure for non-adiabatic and frictional compressible flow. .... imply that application of surface heat flux results in the heating process of the flowing air, causing ...

  2. Efficient numerical integration of neutrino oscillations in matter

    CERN Document Server

    Casas, Fernando; D'Olivo, Juan Carlos

    2016-01-01

    A special purpose solver, based on the Magnus expansion, well suited for the integration of the linear three neutrino oscillations equations in matter is proposed. The computations are speeded up to two orders of magnitude with respect to a general numerical integrator, a fact that could smooth the way for massive numerical integration concomitant with experimental data analyses. Detailed illustrations about numerical procedure and computer time costs are provided.

  3. Multirate Numerical Integration for Parabolic PDEs

    Science.gov (United States)

    Savcenco, Valeriu; Savcenco, Eugeniu

    2008-09-01

    To solve PDE problems with different time scales that are localized in space, multirate time integration is examined. This technique enables one to use large time steps for slowly time-varying spatial regions, and small steps for rapidly varying ones. Multirate time stepping is coupled with the local uniform grid refinement and provides a robust and efficient method for the target problem class. We primarily consider implicit time stepping methods, suitable for parabolic problems. Numerical results are presented for a test problem.

  4. A numerical analytical investigation of lee cyclogenesis.

    OpenAIRE

    Hayes, John L.

    1985-01-01

    Approved for public release; distribution is unlimited The effect of topography on the evolution of a disturbance in a baroclinically unstable mean flow is studied using analytical and numerical simulations. In particular, dynamical mechanisms involved in cyclogenesis in the lee of long, meridional barriers similar to the Rocky Mountains are explored. The rapid growth observed in lee cyclogenesis is highly dependent on the superposition of a growing baroclinic wave with a ...

  5. Numerical classification of soils and its application in survey

    NARCIS (Netherlands)

    Gruijter, de J.J.

    1977-01-01

    Numerical classification of soils was studied with emphasis on methodology and feasibility in survey. A procedure was designed for construction of classes sufficiently homogeneous in terms of relevant properties and handlable by the surveyor. In the procedure 'central' depth-profiles are

  6. Introduction to Numerical Methods

    Energy Technology Data Exchange (ETDEWEB)

    Schoonover, Joseph A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-14

    These are slides for a lecture for the Parallel Computing Summer Research Internship at the National Security Education Center. This gives an introduction to numerical methods. Repetitive algorithms are used to obtain approximate solutions to mathematical problems, using sorting, searching, root finding, optimization, interpolation, extrapolation, least squares regresion, Eigenvalue problems, ordinary differential equations, and partial differential equations. Many equations are shown. Discretizations allow us to approximate solutions to mathematical models of physical systems using a repetitive algorithm and introduce errors that can lead to numerical instabilities if we are not careful.

  7. Numerical wave interaction with tetrapods breakwater

    Directory of Open Access Journals (Sweden)

    Dentale Fabio

    2014-12-01

    Full Text Available The paper provides some results of a new procedure to analyze the hydrodynamic aspects of the interactions between maritime emerged breakwaters and waves by integrating CAD and CFD. The structure is modeled in the numerical domain by overlapping individual three-dimensional elements (Tetrapods, very much like the real world or physical laboratory testing. Flow of the fluid within the interstices among concrete blocks is evaluated by integrating the RANS equations. The aim is to investigate the reliability of this approach as a design tool. Therefore, for the results' validation, the numerical run-up and reflection effects on virtual breakwater were compared with some empirical formulae and some similar laboratory tests. Here are presented the results of a first simple validation procedure. The validation shows that, at present, this innovative approach can be used in the breakwater design phase for comparison between several design solutions with a significant minor cost.

  8. Numerical wave interaction with tetrapods breakwater

    Directory of Open Access Journals (Sweden)

    Fabio Dentale

    2014-12-01

    Full Text Available The paper provides some results of a new procedure to analyze the hydrodynamic aspects of the interactions between maritime emerged breakwaters and waves by integrating CAD and CFD. The structure is modeled in the numerical domain by overlapping individual three-dimensional elements (Tetrapods, very much like the real world or physical laboratory testing. Flow of the fluid within the interstices among concrete blocks is evaluated by integrating the RANS equations. The aim is to investigate the reliability of this approach as a design tool. Therefore, for the results’ validation, the numerical run-up and reflection effects on virtual breakwater were compared with some empirical formulae and some similar laboratory tests. Here are presented the results of a first simple validation procedure. The validation shows that, at present, this innovative approach can be used in the breakwater design phase for comparison between several design solutions with a significant minor cost.

  9. NUMERICAL SIMULATION OF SHOCK WAVE REFRACTION ON INCLINED CONTACT DISCONTINUITY

    Directory of Open Access Journals (Sweden)

    P. V. Bulat

    2016-05-01

    Full Text Available We consider numerical simulation of shock wave refraction on plane contact discontinuity, separating two gases with different density. Discretization of Euler equations is based on finite volume method and WENO finite difference schemes, implemented on unstructured meshes. Integration over time is performed with the use of the third-order Runge–Kutta stepping procedure. The procedure of identification and classification of gas dynamic discontinuities based on conditions of dynamic consistency and image processing methods is applied to visualize and interpret the results of numerical calculations. The flow structure and its quantitative characteristics are defined. The results of numerical and experimental visualization (shadowgraphs, schlieren images, and interferograms are compared.

  10. Reduced-order modelling numerical homogenization.

    Science.gov (United States)

    Abdulle, A; Bai, Y

    2014-08-06

    A general framework to combine numerical homogenization and reduced-order modelling techniques for partial differential equations (PDEs) with multiple scales is described. Numerical homogenization methods are usually efficient to approximate the effective solution of PDEs with multiple scales. However, classical numerical homogenization techniques require the numerical solution of a large number of so-called microproblems to approximate the effective data at selected grid points of the computational domain. Such computations become particularly expensive for high-dimensional, time-dependent or nonlinear problems. In this paper, we explain how numerical homogenization method can benefit from reduced-order modelling techniques that allow one to identify offline and online computational procedures. The effective data are only computed accurately at a carefully selected number of grid points (offline stage) appropriately 'interpolated' in the online stage resulting in an online cost comparable to that of a single-scale solver. The methodology is presented for a class of PDEs with multiple scales, including elliptic, parabolic, wave and nonlinear problems. Numerical examples, including wave propagation in inhomogeneous media and solute transport in unsaturated porous media, illustrate the proposed method. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  11. Numerical Methods in Linguistics

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 10; Issue 1. Numerical Methods in Linguistics - An Introduction to Glottochronology. Raamesh Gowri Raghavan. General Article Volume 10 Issue 1 January 2005 pp 17-24. Fulltext. Click here to view fulltext PDF. Permanent link:

  12. The legibility of numerals

    DEFF Research Database (Denmark)

    Beier, Sofie

    2017-01-01

    , there is no additional help from the surrounding numbers or from the structure of the text. It is therefore essential that one number not be mistaken for another. In spite of this, there is very little relevant research on numeral legibility. In this talk I will review existing knowledge and present the findings...

  13. Numerical analysis using Sage

    CERN Document Server

    Anastassiou, George A

    2015-01-01

    This is the first numerical analysis text to use Sage for the implementation of algorithms and can be used in a one-semester course for undergraduates in mathematics, math education, computer science/information technology, engineering, and physical sciences. The primary aim of this text is to simplify understanding of the theories and ideas from a numerical analysis/numerical methods course via a modern programming language like Sage. Aside from the presentation of fundamental theoretical notions of numerical analysis throughout the text, each chapter concludes with several exercises that are oriented to real-world application.  Answers may be verified using Sage.  The presented code, written in core components of Sage, are backward compatible, i.e., easily applicable to other software systems such as Mathematica®.  Sage is  open source software and uses Python-like syntax. Previous Python programming experience is not a requirement for the reader, though familiarity with any programming language is a p...

  14. Status of numerical relativity

    Indian Academy of Sciences (India)

    Numerical relativity; gravitational waves; black hole; neutron star. ... and stellar collapse, emphasizing the well-developed current status of such implementations that enable simulations for several astrophysical phenomena. Some of our latest results for simulation of binary neutron star mergers are briefly presented.

  15. Status of numerical relativity

    Indian Academy of Sciences (India)

    schemes are described in [48]. 2.5 Black hole finder. In many simulations of numerical relativity, black holes are formed or exist from the beginning of simulation (e.g., in merger of binary black holes). To confirm the existence of black holes and to find their location, apparent horizon finder and/or event horizon finder have to ...

  16. Varieties of numerical abilities.

    Science.gov (United States)

    Dehaene, S

    1992-08-01

    This paper provides a tutorial introduction to numerical cognition, with a review of essential findings and current points of debate. A tacit hypothesis in cognitive arithmetic is that numerical abilities derive from human linguistic competence. One aim of this special issue is to confront this hypothesis with current knowledge of number representations in animals, infants, normal and gifted adults, and brain-lesioned patients. First, the historical evolution of number notations is presented, together with the mental processes for calculating and transcoding from one notation to another. While these domains are well described by formal symbol-processing models, this paper argues that such is not the case for two other domains of numerical competence: quantification and approximation. The evidence for counting, subitizing and numerosity estimation in infants, children, adults and animals is critically examined. Data are also presented which suggest a specialization for processing approximate numerical quantities in animals and humans. A synthesis of these findings is proposed in the form of a triple-code model, which assumes that numbers are mentally manipulated in an arabic, verbal or analogical magnitude code depending on the requested mental operation. Only the analogical magnitude representation seems available to animals and preverbal infants.

  17. Developments in Numerical Ecology

    African Journals Online (AJOL)

    methods, fractal theory, path analysis, spatial analysis and a series of ... Indeed, it should be recommended reading for Masters and Doctoral ... technique chosen. In short, this book is truly about the integrated methodology of numerical ecology, and not about the perhaps paradoxical field of theoretical ecology. As the ...

  18. Analysis of numerical methods

    CERN Document Server

    Isaacson, Eugene

    1994-01-01

    This excellent text for advanced undergraduates and graduate students covers norms, numerical solution of linear systems and matrix factoring, iterative solutions of nonlinear equations, eigenvalues and eigenvectors, polynomial approximation, and other topics. It offers a careful analysis and stresses techniques for developing new methods, plus many examples and problems. 1966 edition.

  19. Bariatric Surgery Procedures

    Science.gov (United States)

    ... Center Access to Care Toolkit EHB Access Toolkit Bariatric Surgery Procedures Bariatric surgical procedures cause weight loss by ... minimally invasive techniques (laparoscopic surgery). The most common bariatric surgery procedures are gastric bypass, sleeve gastrectomy, adjustable gastric ...

  20. Handbook of numerical analysis

    CERN Document Server

    Ciarlet, Philippe G

    Mathematical finance is a prolific scientific domain in which there exists a particular characteristic of developing both advanced theories and practical techniques simultaneously. Mathematical Modelling and Numerical Methods in Finance addresses the three most important aspects in the field: mathematical models, computational methods, and applications, and provides a solid overview of major new ideas and results in the three domains. Coverage of all aspects of quantitative finance including models, computational methods and applications Provides an overview of new ideas an

  1. Hybrid undulator numerical optimization

    Energy Technology Data Exchange (ETDEWEB)

    Hairetdinov, A.H. [Kurchatov Institute, Moscow (Russian Federation); Zukov, A.A. [Solid State Physics Institute, Chernogolovka (Russian Federation)

    1995-12-31

    3D properties of the hybrid undulator scheme arc studied numerically using PANDIRA code. It is shown that there exist two well defined sets of undulator parameters which provide either maximum on-axis field amplitude or minimal higher harmonics amplitude of the basic undulator field. Thus the alternative between higher field amplitude or pure sinusoidal field exists. The behavior of the undulator field amplitude and harmonics structure for a large set of (undulator gap)/(undulator wavelength) values is demonstrated.

  2. Simplices for Numeral Systems

    OpenAIRE

    Solus, Liam

    2017-01-01

    The family of lattice simplices in $\\mathbb{R}^n$ formed by the convex hull of the standard basis vectors together with a weakly decreasing vector of negative integers include simplices that play a central role in problems in enumerative algebraic geometry and mirror symmetry. From this perspective, it is useful to have formulae for their discrete volumes via Ehrhart $h^\\ast$-polynomials. Here we show, via an association with numeral systems, that such simplices yield $h^\\ast$-polynomials wit...

  3. Numerical analysis II essentials

    CERN Document Server

    REA, The Editors of; Staff of Research Education Association

    1989-01-01

    REA's Essentials provide quick and easy access to critical information in a variety of different fields, ranging from the most basic to the most advanced. As its name implies, these concise, comprehensive study guides summarize the essentials of the field covered. Essentials are helpful when preparing for exams, doing homework and will remain a lasting reference source for students, teachers, and professionals. Numerical Analysis II covers simultaneous linear systems and matrix methods, differential equations, Fourier transformations, partial differential equations, and Monte Carlo methods.

  4. The Deployable Operations Group: A Model for a National Unified Interagency Rapid Response Command

    National Research Council Canada - National Science Library

    Cooper, Eric M

    2008-01-01

    .... Since the attacks, nationwide preparedness efforts have established numerous federal rapid response teams, which are coordinated during a federal interagency response under the National Incident Management System...

  5. Numerical methods for stochastic differential equations

    Science.gov (United States)

    Kloeden, Peter; Platen, Eckhard

    1991-06-01

    The numerical analysis of stochastic differential equations differs significantly from that of ordinary differential equations due to the peculiarities of stochastic calculus. This book provides an introduction to stochastic calculus and stochastic differential equations, both theory and applications. The main emphasise is placed on the numerical methods needed to solve such equations. It assumes an undergraduate background in mathematical methods typical of engineers and physicists, through many chapters begin with a descriptive summary which may be accessible to others who only require numerical recipes. To help the reader develop an intuitive understanding of the underlying mathematicals and hand-on numerical skills exercises and over 100 PC Exercises (PC-personal computer) are included. The stochastic Taylor expansion provides the key tool for the systematic derivation and investigation of discrete time numerical methods for stochastic differential equations. The book presents many new results on higher order methods for strong sample path approximations and for weak functional approximations, including implicit, predictor-corrector, extrapolation and variance-reduction methods. Besides serving as a basic text on such methods. the book offers the reader ready access to a large number of potential research problems in a field that is just beginning to expand rapidly and is widely applicable.

  6. Rapid Prototyping Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The ARDEC Rapid Prototyping (RP) Laboratory was established in December 1992 to provide low cost RP capabilities to the ARDEC engineering community. The Stratasys,...

  7. Effect of rapid maxillary expansion on sleep characteristics in children

    National Research Council Canada - National Science Library

    Ashok, Navya; Varma, N K Sapna; Ajith, V V; Gopinath, Siby

    2014-01-01

    Rapid maxillary expansion (RME) is an orthopedic treatment procedure routinely used to treat constricted maxillary arches and also a potential additional treatment in children presenting with sleep-disordered breathing (SDB...

  8. Effect of rapid maxillary expansion on sleep characteristics in children

    National Research Council Canada - National Science Library

    Navya Ashok; N. K. Sapna Varma; V V Ajith; Siby Gopinath

    2014-01-01

    Introduction: Rapid maxillary expansion (RME) is an orthopedic treatment procedure routinely used to treat constricted maxillary arches and also a potential additional treatment in children presenting with sleep-disordered breathing (SDB...

  9. Numerical Analysis Objects

    Science.gov (United States)

    Henderson, Michael

    1997-08-01

    The Numerical Analysis Objects project (NAO) is a project in the Mathematics Department of IBM's TJ Watson Research Center. While there are plenty of numerical tools available today, it is not an easy task to combine them into a custom application. NAO is directed at the dual problems of building applications from a set of tools, and creating those tools. There are several "reuse" projects, which focus on the problems of identifying and cataloging tools. NAO is directed at the specific context of scientific computing. Because the type of tools is restricted, problems such as tools with incompatible data structures for input and output, and dissimilar interfaces to tools which solve similar problems can be addressed. The approach we've taken is to define interfaces to those objects used in numerical analysis, such as geometries, functions and operators, and to start collecting (and building) a set of tools which use these interfaces. We have written a class library (a set of abstract classes and implementations) in C++ which demonstrates the approach. Besides the classes, the class library includes "stub" routines which allow the library to be used from C or Fortran, and an interface to a Visual Programming Language. The library has been used to build a simulator for petroleum reservoirs, using a set of tools for discretizing nonlinear differential equations that we have written, and includes "wrapped" versions of packages from the Netlib repository. Documentation can be found on the Web at "http://www.research.ibm.com/nao". I will describe the objects and their interfaces, and give examples ranging from mesh generation to solving differential equations.

  10. Numerical differential protection

    CERN Document Server

    Ziegler, Gerhard

    2012-01-01

    Differential protection is a fast and selective method of protection against short-circuits. It is applied in many variants for electrical machines, trans?formers, busbars, and electric lines.Initially this book covers the theory and fundamentals of analog and numerical differential protection. Current transformers are treated in detail including transient behaviour, impact on protection performance, and practical dimensioning. An extended chapter is dedicated to signal transmission for line protection, in particular, modern digital communication and GPS timing.The emphasis is then pla

  11. Simulation Model of Bus Rapid Transit

    Directory of Open Access Journals (Sweden)

    Gunawan Fergyanto E.

    2014-03-01

    Full Text Available Bus rapid transit system is modern solution for mass transportation system. The system, in comparison to the rail-based transportation system, is significantly cheaper and requires shorter development time, but lower performance. The BRT system performance strongly depends on variables related to station design and infrastructure. A numerical model offers an effective and efficient means to evaluate the system performance. This article offers a detailed numerical model on the basis of the discrete-event approach and demonstrates its application.

  12. A scoping review of rapid review methods.

    Science.gov (United States)

    Tricco, Andrea C; Antony, Jesmin; Zarin, Wasifa; Strifler, Lisa; Ghassemi, Marco; Ivory, John; Perrier, Laure; Hutton, Brian; Moher, David; Straus, Sharon E

    2015-09-16

    Rapid reviews are a form of knowledge synthesis in which components of the systematic review process are simplified or omitted to produce information in a timely manner. Although numerous centers are conducting rapid reviews internationally, few studies have examined the methodological characteristics of rapid reviews. We aimed to examine articles, books, and reports that evaluated, compared, used or described rapid reviews or methods through a scoping review. MEDLINE, EMBASE, the Cochrane Library, internet websites of rapid review producers, and reference lists were searched to identify articles for inclusion. Two reviewers independently screened literature search results and abstracted data from included studies. Descriptive analysis was conducted. We included 100 articles plus one companion report that were published between 1997 and 2013. The studies were categorized as 84 application papers, seven development papers, six impact papers, and four comparison papers (one was included in two categories). The rapid reviews were conducted between 1 and 12 months, predominantly in Europe (58 %) and North America (20 %). The included studies failed to report 6 % to 73 % of the specific systematic review steps examined. Fifty unique rapid review methods were identified; 16 methods occurred more than once. Streamlined methods that were used in the 82 rapid reviews included limiting the literature search to published literature (24 %) or one database (2 %), limiting inclusion criteria by date (68 %) or language (49 %), having one person screen and another verify or screen excluded studies (6 %), having one person abstract data and another verify (23 %), not conducting risk of bias/quality appraisal (7 %) or having only one reviewer conduct the quality appraisal (7 %), and presenting results as a narrative summary (78 %). Four case studies were identified that compared the results of rapid reviews to systematic reviews. Three studies found that the conclusions between

  13. MR sequences and rapid acquisition for MR guided interventions

    Science.gov (United States)

    Campbell-Washburn, Adrienne E; Faranesh, Anthony Z; Lederman, Robert J; Hansen, Michael S

    2015-01-01

    Synopsis Interventional MR uses rapid imaging to guide diagnostic and therapeutic procedures. One of the attractions of MR-guidance is the abundance of inherent contrast mechanisms available. Dynamic procedural guidance with real-time imaging has pushed the limits of MR technology, demanding rapid acquisition and reconstruction paired with interactive control and device visualization. This article reviews the technical aspects of real-time MR sequences that enable MR-guided interventions. PMID:26499283

  14. Confidence in Numerical Simulations

    Energy Technology Data Exchange (ETDEWEB)

    Hemez, Francois M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-02-23

    This PowerPoint presentation offers a high-level discussion of uncertainty, confidence and credibility in scientific Modeling and Simulation (M&S). It begins by briefly evoking M&S trends in computational physics and engineering. The first thrust of the discussion is to emphasize that the role of M&S in decision-making is either to support reasoning by similarity or to “forecast,” that is, make predictions about the future or extrapolate to settings or environments that cannot be tested experimentally. The second thrust is to explain that M&S-aided decision-making is an exercise in uncertainty management. The three broad classes of uncertainty in computational physics and engineering are variability and randomness, numerical uncertainty and model-form uncertainty. The last part of the discussion addresses how scientists “think.” This thought process parallels the scientific method where by a hypothesis is formulated, often accompanied by simplifying assumptions, then, physical experiments and numerical simulations are performed to confirm or reject the hypothesis. “Confidence” derives, not just from the levels of training and experience of analysts, but also from the rigor with which these assessments are performed, documented and peer-reviewed.

  15. Numerical Propulsion System Simulation

    Science.gov (United States)

    Naiman, Cynthia

    2006-01-01

    The NASA Glenn Research Center, in partnership with the aerospace industry, other government agencies, and academia, is leading the effort to develop an advanced multidisciplinary analysis environment for aerospace propulsion systems called the Numerical Propulsion System Simulation (NPSS). NPSS is a framework for performing analysis of complex systems. The initial development of NPSS focused on the analysis and design of airbreathing aircraft engines, but the resulting NPSS framework may be applied to any system, for example: aerospace, rockets, hypersonics, power and propulsion, fuel cells, ground based power, and even human system modeling. NPSS provides increased flexibility for the user, which reduces the total development time and cost. It is currently being extended to support the NASA Aeronautics Research Mission Directorate Fundamental Aeronautics Program and the Advanced Virtual Engine Test Cell (AVETeC). NPSS focuses on the integration of multiple disciplines such as aerodynamics, structure, and heat transfer with numerical zooming on component codes. Zooming is the coupling of analyses at various levels of detail. NPSS development includes capabilities to facilitate collaborative engineering. The NPSS will provide improved tools to develop custom components and to use capability for zooming to higher fidelity codes, coupling to multidiscipline codes, transmitting secure data, and distributing simulations across different platforms. These powerful capabilities extend NPSS from a zero-dimensional simulation tool to a multi-fidelity, multidiscipline system-level simulation tool for the full development life cycle.

  16. Numerical relativity beyond astrophysics

    Science.gov (United States)

    Garfinkle, David

    2017-01-01

    Though the main applications of computer simulations in relativity are to astrophysical systems such as black holes and neutron stars, nonetheless there are important applications of numerical methods to the investigation of general relativity as a fundamental theory of the nature of space and time. This paper gives an overview of some of these applications. In particular we cover (i) investigations of the properties of spacetime singularities such as those that occur in the interior of black holes and in big bang cosmology. (ii) investigations of critical behavior at the threshold of black hole formation in gravitational collapse. (iii) investigations inspired by string theory, in particular analogs of black holes in more than 4 spacetime dimensions and gravitational collapse in spacetimes with a negative cosmological constant.

  17. Numerical relativity beyond astrophysics.

    Science.gov (United States)

    Garfinkle, David

    2017-01-01

    Though the main applications of computer simulations in relativity are to astrophysical systems such as black holes and neutron stars, nonetheless there are important applications of numerical methods to the investigation of general relativity as a fundamental theory of the nature of space and time. This paper gives an overview of some of these applications. In particular we cover (i) investigations of the properties of spacetime singularities such as those that occur in the interior of black holes and in big bang cosmology. (ii) investigations of critical behavior at the threshold of black hole formation in gravitational collapse. (iii) investigations inspired by string theory, in particular analogs of black holes in more than 4 spacetime dimensions and gravitational collapse in spacetimes with a negative cosmological constant.

  18. A New Iterative Numerical Continuation Technique for Approximating the Solutions of Scalar Nonlinear Equations

    Directory of Open Access Journals (Sweden)

    Grégory Antoni

    2017-01-01

    Full Text Available The present study concerns the development of a new iterative method applied to a numerical continuation procedure for parameterized scalar nonlinear equations. Combining both a modified Newton’s technique and a stationary-type numerical procedure, the proposed method is able to provide suitable approximate solutions associated with scalar nonlinear equations. A numerical analysis of predictive capabilities of this new iterative algorithm is addressed, assessed, and discussed on some specific examples.

  19. Computer numeric control generation of toric surfaces

    Science.gov (United States)

    Bradley, Norman D.; Ball, Gary A.; Keller, John R.

    1994-05-01

    Until recently, the manufacture of toric ophthalmic lenses relied largely upon expensive, manual techniques for generation and polishing. Recent gains in computer numeric control (CNC) technology and tooling enable lens designers to employ single- point diamond, fly-cutting methods in the production of torics. Fly-cutting methods continue to improve, significantly expanding lens design possibilities while lowering production costs. Advantages of CNC fly cutting include precise control of surface geometry, rapid production with high throughput, and high-quality lens surface finishes requiring minimal polishing. As accessibility and affordability increase within the ophthalmic market, torics promise to dramatically expand lens design choices available to consumers.

  20. Rapid, generalized adaptation to asynchronous audiovisual speech.

    Science.gov (United States)

    Van der Burg, Erik; Goodbourn, Patrick T

    2015-04-07

    The brain is adaptive. The speed of propagation through air, and of low-level sensory processing, differs markedly between auditory and visual stimuli; yet the brain can adapt to compensate for the resulting cross-modal delays. Studies investigating temporal recalibration to audiovisual speech have used prolonged adaptation procedures, suggesting that adaptation is sluggish. Here, we show that adaptation to asynchronous audiovisual speech occurs rapidly. Participants viewed a brief clip of an actor pronouncing a single syllable. The voice was either advanced or delayed relative to the corresponding lip movements, and participants were asked to make a synchrony judgement. Although we did not use an explicit adaptation procedure, we demonstrate rapid recalibration based on a single audiovisual event. We find that the point of subjective simultaneity on each trial is highly contingent upon the modality order of the preceding trial. We find compelling evidence that rapid recalibration generalizes across different stimuli, and different actors. Finally, we demonstrate that rapid recalibration occurs even when auditory and visual events clearly belong to different actors. These results suggest that rapid temporal recalibration to audiovisual speech is primarily mediated by basic temporal factors, rather than higher-order factors such as perceived simultaneity and source identity. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  1. IC Treatment: Surgical Procedures

    Science.gov (United States)

    ... Profile Home Diagnosis & Treatment IC Treatments Surgical Procedures Surgical Procedures For people with interstitial cystitis (IC), the ... latest stories, news and events. Please leave this field empty Interstitial Cystitis Association 7918 Jones Branch Drive, ...

  2. Numerical Methods in Fluid Dynamics.

    Science.gov (United States)

    treatment of time-dependent three-dimensional flows; Un example de modele mathematique complexe en mecanique des fluides ....des equations de Navier-Stokes des fluides visqueux incompressibles; Numerical solution of steady state Navier-Stokes equations; Numerical solution of...dynamics; Application of finite elements methods in fluid dynamics; Computational methods for inviscid transonic flows with inbedded shock waves; Numerical

  3. The procedural egalitarian solution

    NARCIS (Netherlands)

    Dietzenbacher, Bas; Borm, Peter; Hendrickx, Ruud

    2017-01-01

    In this paper we introduce and analyze the procedural egalitarian solution for transferable utility games. This new concept is based on the result of a coalitional bargaining procedure in which egalitarian considerations play a central role. The procedural egalitarian solution is the first

  4. The Procedural Egalitarian Solution

    NARCIS (Netherlands)

    Dietzenbacher, Bas; Borm, Peter; Hendrickx, Ruud

    2016-01-01

    In this paper we introduce and analyze the procedural egalitarian solution for transferable utility games. This new concept is based on the result of a coalitional bargaining procedure in which egalitarian considerations play a central role. The procedural egalitarian solution is the first

  5. Numerical model SMODERP

    Science.gov (United States)

    Kavka, P.; Jeřábek, J.; Strouhal, L.

    2016-12-01

    The contribution presents a numerical model SMODERP that is used for calculation and prediction of surface runoff and soil erosion from agricultural land. The physically based model includes the processes of infiltration (Phillips equation), surface runoff routing (kinematic wave based equation), surface retention, surface roughness and vegetation impact on runoff. The model is being developed at the Department of Irrigation, Drainage and Landscape Engineering, Civil Engineering Faculty, CTU in Prague. 2D version of the model was introduced in last years. The script uses ArcGIS system tools for data preparation. The physical relations are implemented through Python scripts. The main computing part is stand alone in numpy arrays. Flow direction is calculated by Steepest Descent algorithm and in multiple flow algorithm. Sheet flow is described by modified kinematic wave equation. Parameters for five different soil textures were calibrated on the set of hundred measurements performed on the laboratory and filed rainfall simulators. Spatially distributed models enable to estimate not only surface runoff but also flow in the rills. Development of the rills is based on critical shear stress and critical velocity. For modelling of the rills a specific sub model was created. This sub model uses Manning formula for flow estimation. Flow in the ditches and streams are also computed. Numerical stability of the model is controled by Courant criterion. Spatial scale is fixed. Time step is dynamic and depends on the actual discharge. The model is used in the framework of the project "Variability of Short-term Precipitation and Runoff in Small Czech Drainage Basins and its Influence on Water Resources Management". Main goal of the project is to elaborate a methodology and online utility for deriving short-term design precipitation series, which could be utilized by a broad community of scientists, state administration as well as design planners. The methodology will account for

  6. Rapid shallow breathing

    Science.gov (United States)

    ... the smallest air passages of the lungs in children ( bronchiolitis ) Pneumonia or other lung infection Transient tachypnea of the newborn Anxiety and panic Other serious lung disease Home Care Rapid, shallow breathing should not be treated at home. It is ...

  7. Rapid Strep Test

    Science.gov (United States)

    ... worse than normal. Your first thoughts turn to strep throat. A rapid strep test in your doctor’s office ... your suspicions.Viruses cause most sore throats. However, strep throat is an infection caused by the Group A ...

  8. Introduction to numerical electrostatics using MATLAB

    CERN Document Server

    Dworsky, Lawrence N

    2014-01-01

    The first of its kind uniquely devoted to the field of computational electrostatics, this book dives headfirst into the actual problems that engineers are expected to solve using method of moment (MoM), finite difference, and finite element techniques. Readers are guided step by step through specific problems and challenges, covering all aspects of electrostatics with an emphasis on numerical procedures. Focusing on practical examples, mathematical equations, and common issues with algorithms, this is an ideal text for students in engineering, physics, and electrostatics-and working engineers

  9. Numerical analysis mathematics of scientific computing

    CERN Document Server

    Kincaid, David

    2009-01-01

    This book introduces students with diverse backgrounds to various types of mathematical analysis that are commonly needed in scientific computing. The subject of numerical analysis is treated from a mathematical point of view, offering a complete analysis of methods for scientific computing with appropriate motivations and careful proofs. In an engaging and informal style, the authors demonstrate that many computational procedures and intriguing questions of computer science arise from theorems and proofs. Algorithms are presented in pseudocode, so that students can immediately write computer

  10. Assigning Numerical Scores to Linguistic Expressions

    Directory of Open Access Journals (Sweden)

    María Jesús Campión

    2017-07-01

    Full Text Available In this paper, we study different methods of scoring linguistic expressions defined on a finite set, in the search for a linear order that ranks all those possible expressions. Among them, particular attention is paid to the canonical extension, and its representability through distances in a graph plus some suitable penalization of imprecision. The relationship between this setting and the classical problems of numerical representability of orderings, as well as extension of orderings from a set to a superset is also explored. Finally, aggregation procedures of qualitative rankings and scorings are also analyzed.

  11. Rapid method for plutonium-241 determination in soil samples

    OpenAIRE

    Piekarz, M.; Komosa, A.

    2014-01-01

    A simple and rapid procedure for the determination of plutonium isotopes in the environment is presented. The procedure combines alpha spectrometry, solvent extraction and liquid scintillation measurements to ensure that both alpha- and beta-emitting isotopes are determined. Of five tested extractants, bis-(2-ethylhexyl) phosphoric acid was found to be the best choice. The procedure was applied to soil samples contaminated with Chernobyl fallout.

  12. RAPID3? Aptly named!

    Science.gov (United States)

    Berthelot, J-M

    2014-01-01

    The RAPID3 score is the sum of three 0-10 patient self-report scores: pain, functional impairment on MDHAQ, and patient global estimate. It requires 5 seconds for scoring and can be used in all rheumatologic conditions, although it has mostly been used in rheumatoid arthritis where cutoffs for low disease activity (12/30) have been set. A RAPID3 score of ≤ 3/30 with 1 or 0 swollen joints (RAPID3 ≤ 3 + ≤ SJ1) provides remission criteria comparable to Boolean, SDAI, CDAI, and DAS28 remission criteria, in far less time than a formal joint count. RAPID3 performs as well as the DAS28 in separating active drugs from placebos in clinical trials. RAPID3 also predicts subsequent structural disease progression. RAPID3 can be determined at short intervals at home, allowing the determination of the area under the curve of disease activity between two visits and flare detection. However, RAPID3 should not be seen as a substitute for DAS28 and face to face visits in routine care. Monitoring patient status with only self-report information without a rheumatologist's advice (including joints and physical examination, and consideration of imaging and laboratory tests) may indeed be as undesirable for most patients than joint examination without a patient questionnaire. Conversely, combining the RAPID3 and the DAS28 may consist in faster or more sensitive confirmation that a medication is effective. Similarly, better enquiring of most important concerns of patients (pain, functional status and overall opinion on their disorder) should reinforces patients' confidence in their rheumatologist and treatments.

  13. Rapid Response Flood Water Mapping

    Science.gov (United States)

    Policelli, Fritz; Brakenridge, G. R.; Coplin, A.; Bunnell, M.; Wu, L.; Habib, Shahid; Farah, H.

    2010-01-01

    Since the beginning of operation of the MODIS instrument on the NASA Terra satellite at the end of 1999, an exceptionally useful sensor and public data stream have been available for many applications including the rapid and precise characterization of terrestrial surface water changes. One practical application of such capability is the near-real time mapping of river flood inundation. We have developed a surface water mapping methodology based on using only bands 1 (620-672 nm) and 2 (841-890 nm). These are the two bands at 250 m, and the use of only these bands maximizes the resulting map detail. In this regard, most water bodies are strong absorbers of incoming solar radiation at the band 2 wavelength: it could be used alone, via a thresholding procedure, to separate water (dark, low radiance or reflectance pixels) from land (much brighter pixels) (1, 2). Some previous water mapping procedures have in fact used such single band data from this and other sensors that include similar wavelength channels. Adding the second channel of data (band 1), however, allows a band ratio approach which permits sediment-laden water, often relatively light at band 2 wavelengths, to still be discriminated, and, as well, provides some removal of error by reducing the number of cloud shadow pixels that would otherwise be misclassified as water.

  14. Numerical methods in metalforming

    Science.gov (United States)

    Rebelo, N.

    1984-09-01

    At the very heart of metal forming analysis is the theory of plasticity. A brief description of this theory is given. The infinitesimal theory of plasticity, simplified by discarding the elastic part of deformation (also known as the flow theory) has produced several approximate methods of analysis that have proved very useful in metal forming. The basic assumptions are presented that lead to the uniform deformation method, the slab method, the upper-bound method and the slip-line field method. The availability of computers with relatively inexpensive, large amounts of number-crunching capabilities fostered the development of the finite element method. Originally used in structural analysis, it rapidly expanded into other fields, and has been applied to metal forming analysis since the early seventies. This is the area in which most of the recent work in this field has been done. The first one is based on the rigid plastic approach (the flow theory) for which the infinitesimal theory of plasticity has been sufficient. It leads to relatively simple formulations which have allowed its users to attack the difficult problems specific to metal forming applications. The second one is based on the more complete elasto-plastic approach which almost always requires a large deformation theory of plasticity. The formulations are more complicated and have followed, if not actually led to, development in the theory itself. This reports ends with an introduction to the fundamental concepts of the finite element method.

  15. Numerical simulation of fractional Cable equation of spiny neuronal dendrites.

    Science.gov (United States)

    Sweilam, N H; Khader, M M; Adel, M

    2014-03-01

    In this article, numerical study for the fractional Cable equation which is fundamental equations for modeling neuronal dynamics is introduced by using weighted average of finite difference methods. The stability analysis of the proposed methods is given by a recently proposed procedure similar to the standard John von Neumann stability analysis. A simple and an accurate stability criterion valid for different discretization schemes of the fractional derivative and arbitrary weight factor is introduced and checked numerically. Numerical results, figures, and comparisons have been presented to confirm the theoretical results and efficiency of the proposed method.

  16. Numerical simulation of fractional Cable equation of spiny neuronal dendrites

    Directory of Open Access Journals (Sweden)

    N.H. Sweilam

    2014-03-01

    Full Text Available In this article, numerical study for the fractional Cable equation which is fundamental equations for modeling neuronal dynamics is introduced by using weighted average of finite difference methods. The stability analysis of the proposed methods is given by a recently proposed procedure similar to the standard John von Neumann stability analysis. A simple and an accurate stability criterion valid for different discretization schemes of the fractional derivative and arbitrary weight factor is introduced and checked numerically. Numerical results, figures, and comparisons have been presented to confirm the theoretical results and efficiency of the proposed method.

  17. Numerical Hydrodynamics and Magnetohydrodynamics in General Relativity

    Directory of Open Access Journals (Sweden)

    Font José A.

    2008-09-01

    Full Text Available This article presents a comprehensive overview of numerical hydrodynamics and magnetohydrodynamics (MHD in general relativity. Some significant additions have been incorporated with respect to the previous two versions of this review (2000, 2003, most notably the coverage of general-relativistic MHD, a field in which remarkable activity and progress has occurred in the last few years. Correspondingly, the discussion of astrophysical simulations in general-relativistic hydrodynamics is enlarged to account for recent relevant advances, while those dealing with general-relativistic MHD are amply covered in this review for the first time. The basic outline of this article is nevertheless similar to its earlier versions, save for the addition of MHD-related issues throughout. Hence, different formulations of both the hydrodynamics and MHD equations are presented, with special mention of conservative and hyperbolic formulations well adapted to advanced numerical methods. A large sample of numerical approaches for solving such hyperbolic systems of equations is discussed, paying particular attention to solution procedures based on schemes exploiting the characteristic structure of the equations through linearized Riemann solvers. As previously stated, a comprehensive summary of astrophysical simulations in strong gravitational fields is also presented. These are detailed in three basic sections, namely gravitational collapse, black-hole accretion, and neutron-star evolutions; despite the boundaries, these sections may (and in fact do overlap throughout the discussion. The material contained in these sections highlights the numerical challenges of various representative simulations. It also follows, to some extent, the chronological development of the field, concerning advances in the formulation of the gravitational field, hydrodynamics and MHD equations and the numerical methodology designed to solve them. To keep the length of this article reasonable

  18. Numerical Hydrodynamics and Magnetohydrodynamics in General Relativity.

    Science.gov (United States)

    Font, José A

    2008-01-01

    This article presents a comprehensive overview of numerical hydrodynamics and magneto-hydrodynamics (MHD) in general relativity. Some significant additions have been incorporated with respect to the previous two versions of this review (2000, 2003), most notably the coverage of general-relativistic MHD, a field in which remarkable activity and progress has occurred in the last few years. Correspondingly, the discussion of astrophysical simulations in general-relativistic hydrodynamics is enlarged to account for recent relevant advances, while those dealing with general-relativistic MHD are amply covered in this review for the first time. The basic outline of this article is nevertheless similar to its earlier versions, save for the addition of MHD-related issues throughout. Hence, different formulations of both the hydrodynamics and MHD equations are presented, with special mention of conservative and hyperbolic formulations well adapted to advanced numerical methods. A large sample of numerical approaches for solving such hyperbolic systems of equations is discussed, paying particular attention to solution procedures based on schemes exploiting the characteristic structure of the equations through linearized Riemann solvers. As previously stated, a comprehensive summary of astrophysical simulations in strong gravitational fields is also presented. These are detailed in three basic sections, namely gravitational collapse, black-hole accretion, and neutron-star evolutions; despite the boundaries, these sections may (and in fact do) overlap throughout the discussion. The material contained in these sections highlights the numerical challenges of various representative simulations. It also follows, to some extent, the chronological development of the field, concerning advances in the formulation of the gravitational field, hydrodynamics and MHD equations and the numerical methodology designed to solve them. To keep the length of this article reasonable, an effort has

  19. Numerical simulation of an intense precipitation event over ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 124; Issue 7. Numerical simulation of an intense precipitation event ... Incursion of moist air, in the lower levels, converges at the foothills of the mountains and rise along the orography to form the updraft zone of the storm. Such rapid unstable ascent leads to deep ...

  20. Rapid repair techniques for severely earthquake-damaged circular bridge piers with flexural failure mode

    Science.gov (United States)

    Sun, Zhiguo; Li, Hongnan; Bi, Kaiming; Si, Bingjun; Wang, Dongsheng

    2017-04-01

    In this study, three rapid repair techniques are proposed to retrofit circular bridge piers that are severely damaged by the flexural failure mode in major earthquakes. The quasi-static tests on three 1:2.5 scaled circular pier specimens are conducted to evaluate the efficiency of the proposed repair techniques. For the purpose of rapid repair, the repair procedure for all the specimens is conducted within four days, and the behavior of the repaired specimens is evaluated and compared with the original ones. A finite element model is developed to predict the cyclic behavior of the repaired specimens and the numerical results are compared with the test data. It is found that all the repaired specimens exhibit similar or larger lateral strength and deformation capacity than the original ones. The initial lateral stiffness of all the repaired specimens is lower than that of the original ones, while they show a higher lateral stiffness at the later stage of the test. No noticeable difference is observed for the energy dissipation capacity between the original and repaired pier specimens. It is suggested that the repair technique using the early-strength concrete jacket confined by carbon fiber reinforced polymer (CFRP) sheets can be an optimal method for the rapid repair of severely earthquake-damaged circular bridge piers with flexural failure mode.

  1. Rapid small lot manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Harrigan, R.W.

    1998-05-09

    The direct connection of information, captured in forms such as CAD databases, to the factory floor is enabling a revolution in manufacturing. Rapid response to very dynamic market conditions is becoming the norm rather than the exception. In order to provide economical rapid fabrication of small numbers of variable products, one must design with manufacturing constraints in mind. In addition, flexible manufacturing systems must be programmed automatically to reduce the time for product change over in the factory and eliminate human errors. Sensor based machine control is needed to adapt idealized, model based machine programs to uncontrolled variables such as the condition of raw materials and fabrication tolerances.

  2. Numerical modelling of mine workings.

    CSIR Research Space (South Africa)

    Lightfoot, N

    1999-03-01

    Full Text Available to eliminate as many problems and mistakes as possible. Sections are included covering details of the actual use of the two common digitising packages. The first example utilises a number of different numerical modelling programs to solve a single problem... and applications of numerical modelling in the context of the South African gold and platinum mining industries. This includes an example that utilises a number of different numerical 3 modelling programs to solve a single problem. This particular example...

  3. New innovations in interventional cardiac procedures - role of ...

    African Journals Online (AJOL)

    SASA Refresher Course Texts: New innovations in interventional cardiac procedures. 66. 2014;20(1). South Afr J Anaesth Analg. The field of interventional cardiac procedures is rapidly growing. Since the “first in men” catheter-based implantation of a biological aortic valve by Cribier,1 the number of transcatheter based ...

  4. Introduction to precise numerical methods

    CERN Document Server

    Aberth, Oliver

    2007-01-01

    Precise numerical analysis may be defined as the study of computer methods for solving mathematical problems either exactly or to prescribed accuracy. This book explains how precise numerical analysis is constructed. The book also provides exercises which illustrate points from the text and references for the methods presented. All disc-based content for this title is now available on the Web. · Clearer, simpler descriptions and explanations ofthe various numerical methods· Two new types of numerical problems; accurately solving partial differential equations with the included software and computing line integrals in the complex plane.

  5. Rapid Cycling and Its Treatment

    Science.gov (United States)

    ... Announcements Public Service Announcements Partnering with DBSA Rapid Cycling and its Treatment What is bipolar disorder? Bipolar ... to Depression and Manic Depression . What is rapid cycling? Rapid cycling is defined as four or more ...

  6. Finite element procedures

    CERN Document Server

    Bathe, Klaus-Jürgen

    2015-01-01

    Finite element procedures are now an important and frequently indispensable part of engineering analyses and scientific investigations. This book focuses on finite element procedures that are very useful and are widely employed. Formulations for the linear and nonlinear analyses of solids and structures, fluids, and multiphysics problems are presented, appropriate finite elements are discussed, and solution techniques for the governing finite element equations are given. The book presents general, reliable, and effective procedures that are fundamental and can be expected to be in use for a long time. The given procedures form also the foundations of recent developments in the field.

  7. A numerical study of hypersonic propulsion/airframe integration problem

    Science.gov (United States)

    Narayan, J. R.; Kumar, A.

    1989-01-01

    A numerical analysis procedure useful in the propulsion-airframe integration problem has been established. Flow around a generic hypersonic vehicle forebody is solved using Parabolized Navier-Stokes equations and Thin Layer Navier-Stokes equations. Forebody cross sectional geometry corresponds to a two-ellipse configuration. Effect of forebody geometry on the flow structure, especially at the engine inlet location, is analyzed.

  8. Numerical analysis of highly deformable elastoplastic beams

    Directory of Open Access Journals (Sweden)

    João Paulo Pascon

    Full Text Available AbstractThe objective of the present study is to develop a numerical formulation to predict the behavior of highly deformable elastoplastic thin beams. Following the Euler-Bernoulli bending, the axial and shear effects are neglected, and the nonlinear second-order differential equation regarding the angle of rotation is defined based on the specific moment-curvature relationship. Although the formulation can be used for general materials, three constitutive models are employed: linear-elastic, bilinear elastoplastic, and linear-elastic with Swift isotropic hardening. The resultant boundary value problem is solved by means of the fourth-order Runge-Kutta integration procedure and the one-parameter nonlinear shooting method. The performance of the present formulation is investigated via three numerical problems involving finite bending of slender beams composed of elastoplastic materials. For these problems, numerical solutions regarding rotations, displacements and strains for the loading, unloading and reloading phases are provided. Finally, it is shown that the present methodology can also be used to determine the post-buckling behavior of elastoplastic thin beams.

  9. Numerical abilities in fish: A methodological review.

    Science.gov (United States)

    Agrillo, Christian; Miletto Petrazzini, Maria Elena; Bisazza, Angelo

    2017-08-01

    The ability to utilize numerical information can be adaptive in a number of ecological contexts including foraging, mating, parental care, and anti-predator strategies. Numerical abilities of mammals and birds have been studied both in natural conditions and in controlled laboratory conditions using a variety of approaches. During the last decade this ability was also investigated in some fish species. Here we reviewed the main methods used to study this group, highlighting the strengths and weaknesses of each of the methods used. Fish have only been studied under laboratory conditions and among the methods used with other species, only two have been systematically used in fish-spontaneous choice tests and discrimination learning procedures. In the former case, the choice between two options is observed in a biologically relevant situation and the degree of preference for the larger/smaller group is taken as a measure of the capacity to discriminate the two quantities (e.g., two shoals differing in number). In discrimination learning tasks, fish are trained to select the larger or the smaller of two sets of abstract objects, typically two-dimensional geometric figures, using food or social companions as reward. Beyond methodological differences, what emerges from the literature is a substantial similarity of the numerical abilities of fish with those of other vertebrates studied. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Rapid manufacturing for microfluidics

    CSIR Research Space (South Africa)

    Land, K

    2012-10-01

    Full Text Available . Microfluidics is at the forefront of developing solutions for drug discovery, diagnostics (from glucose tests to malaria and TB testing) and environmental diagnostics (E-coli monitoring of drinking water). In order to quickly implement new designs, a rapid...

  11. Rapid Prototyping in PVS

    Science.gov (United States)

    Munoz, Cesar A.; Butler, Ricky (Technical Monitor)

    2003-01-01

    PVSio is a conservative extension to the PVS prelude library that provides basic input/output capabilities to the PVS ground evaluator. It supports rapid prototyping in PVS by enhancing the specification language with built-in constructs for string manipulation, floating point arithmetic, and input/output operations.

  12. Rapid Prototyping Reconsidered

    Science.gov (United States)

    Desrosier, James

    2011-01-01

    Continuing educators need additional strategies for developing new programming that can both reduce the time to market and lower the cost of development. Rapid prototyping, a time-compression technique adapted from the high technology industry, represents one such strategy that merits renewed evaluation. Although in higher education rapid…

  13. Trypanosomatid protozoa: a simplified DNA isolation procedure.

    Science.gov (United States)

    Rotureau, Brice; Gego, Audrey; Carme, Bernard

    2005-11-01

    A non-toxic and versatile protein salting-out DNA extraction method is here described for convenient and rapid extraction of nuclear DNA molecules from trypanosomatids. The procedure just involves four manipulations, does not require any organic solvent, and is performed in less than 1h in a single tube. DNA yields obtained were similar to those from commercial kits and phenol-chloroform procedures. Samples extracted by this method were suitable for PCR and subsequent analyses. The reduced manual labour involved was perceived as an important benefit in medical diagnosis routine use as well as for large-scale taxonomic and eco-epidemiological studies of trypanosomatids.

  14. Field experiment and numerical simulation of point source irrigation with multiple tracers.

    Science.gov (United States)

    Selim, Tarek; Bouksila, Fethi; Hamed, Yasser; Berndtsson, Ronny; Bahri, Akissa; Persson, Magnus

    2018-01-01

    Dyes like Brilliant Blue have similar adsorptive behaviour as some organic contaminants, e.g., pesticides. Bromide ions, on the other hand, move much like NO3-N (fertilizer) in soil. Consequently, by using these two tracers, it is possible to in a general way mimic how organic contaminants and fertilizers may move through soils. Three plots with sandy soil in semiarid Tunisia were irrigated during three successive hours using a single irrigation dripper and high-saline solution (10.50 dS m-1) containing dye and bromide. Fifteen hours after cease of infiltration, horizontal 5 cm trenches were dug in the soil and dye pattern, bromide concentration, and soil water content were recorded. Preferential flow occurred to some degree, however, it did not dominate the solute transport process. Therefore, drip irrigation can be recommended to improve plant culture for a better water and soil nutrient adsorption. Numerical simulation using HYDRUS-2D/3D was performed to replicate the field experiments. Observed soil water contents before and after infiltration were used to run an inverse parameter estimation procedure to identify soil hydraulic parameters. It was found that for both field experiments and numerical simulations the mobility of bromide is different from the mobility of dye. The dye was retarded approximately twice by volume as compared to bromide. The simulation results support the use of HYDRUS-2D/3D as a rapid and labor saving tool for investigating tracers' mobility in sandy soil under point source irrigation.

  15. Civil Procedure In Denmark

    DEFF Research Database (Denmark)

    Werlauff, Erik

    The book contains an up-to-date survey of Danish civil procedure after the profound Danish procedural reforms in 2007. It deals with questions concerning competence and function of Danish courts, commencement and preparation of civil cases, questions of evidence and burden of proof, international...

  16. Decision-making Procedures

    DEFF Research Database (Denmark)

    Aldashev, Gani; Kirchsteiger, Georg; Sebald, Alexander Christopher

    2009-01-01

    It is a persistent finding in psychology and experimental economics that people's behavior is not only shaped by outcomes but also by decision-making procedures. In this paper we develop a general framework capable of modelling these procedural concerns. Within the context of psychological games we...

  17. How to Circumvent Church Numerals

    DEFF Research Database (Denmark)

    Goldberg, Mayer; Torgersen, Mads

    2002-01-01

    In this work we consider a standard numeral system in the lambda-calculus, and the elementary arithmetic and Boolean functions and predicates defined on this numeral system, and show how to construct terms that "circumvent" or "defeat" these functions: The equality predicate is satisfied when...

  18. Physical modeling versus numerical modeling

    NARCIS (Netherlands)

    Blacquière, G.; Veldhuizen, E. van

    2003-01-01

    Despite the widespread use of numerical modeling, there is still room for physical modeling today for many reasons. E.g., physical modeling is based on real wave propagation whereas numerical modeling is based on algorithms which are by necessity simplified and discretized versions of the 'real

  19. Rapid enterprise design

    NARCIS (Netherlands)

    Mulder, J.B.F.

    2006-01-01

    Existing methods for redesigning organizations are often not capable of meeting the required rate of change. This applies in particular to development methods for IT applications: the average automation procedure takes around two years to implement. Therefore, there is an urgent need for methods

  20. Play vs. Procedures

    DEFF Research Database (Denmark)

    Hammar, Emil

    Through the theories of play by Gadamer (2004) and Henricks (2006), I will show how the relationship between play and game can be understood as dialectic and disruptive, thus challenging understandings of how the procedures of games determine player activity and vice versa. As such, I posit some...... analytical consequences for understandings of digital games as procedurally fixed (Boghost, 2006; Flannagan, 2009; Bathwaite & Sharp, 2010). That is, if digital games are argued to be procedurally fixed and if play is an appropriative and dialectic activity, then it could be argued that the latter affects...... and alters the former, and vice versa. Consequently, if the appointed procedures of a game are no longer fixed and rigid in their conveyance of meaning, qua the appropriative and dissolving nature of play, then understandings of games as conveying a fixed meaning through their procedures are inadequate...

  1. Rapid purification of recombinant histones.

    Directory of Open Access Journals (Sweden)

    Henrike Klinker

    Full Text Available The development of methods to assemble nucleosomes from recombinant histones decades ago has transformed chromatin research. Nevertheless, nucleosome reconstitution remains time consuming to this day, not least because the four individual histones must be purified first. Here, we present a streamlined purification protocol of recombinant histones from bacteria. We termed this method "rapid histone purification" (RHP as it circumvents isolation of inclusion bodies and thereby cuts out the most time-consuming step of traditional purification protocols. Instead of inclusion body isolation, whole cell extracts are prepared under strongly denaturing conditions that directly solubilize inclusion bodies. By ion exchange chromatography, the histones are purified from the extracts. The protocol has been successfully applied to all four canonical Drosophila and human histones. RHP histones and histones that were purified from isolated inclusion bodies had similar purities. The different purification strategies also did not impact the quality of octamers reconstituted from these histones. We expect that the RHP protocol can be readily applied to the purification of canonical histones from other species as well as the numerous histone variants.

  2. Introduction to the numerical solutions of Markov chains

    CERN Document Server

    Stewart, Williams J

    1994-01-01

    A cornerstone of applied probability, Markov chains can be used to help model how plants grow, chemicals react, and atoms diffuse - and applications are increasingly being found in such areas as engineering, computer science, economics, and education. To apply the techniques to real problems, however, it is necessary to understand how Markov chains can be solved numerically. In this book, the first to offer a systematic and detailed treatment of the numerical solution of Markov chains, William Stewart provides scientists on many levels with the power to put this theory to use in the actual world, where it has applications in areas as diverse as engineering, economics, and education. His efforts make for essential reading in a rapidly growing field. Here, Stewart explores all aspects of numerically computing solutions of Markov chains, especially when the state is huge. He provides extensive background to both discrete-time and continuous-time Markov chains and examines many different numerical computing metho...

  3. Numerical modeling transport phenomena in proton exchange membrane fuel cells

    Science.gov (United States)

    Suh, DongMyung

    To study the coupled phenomena occurring in proton exchange membrane fuel cells, a two-phase, one-dimensional, non-isothermal model is developed in the chapter 1. The model includes water phase change, proton transport in the membrane and electro-osmotic effect. The thinnest, but most complex layer in the membrane electrode assembly, catalyst layer, is considered an interfacial boundary between the gas diffusion layer and the membrane. Mass and heat transfer and electro-chemical reaction through the catalyst layer are formulated into equations, which are applied to boundary conditions for the gas diffusion layer and the membrane. Detail accounts of the boundary equations and the numerical solving procedure used in this work are given. The polarization curve is calculated at different oxygen pressures and compared with the experimental results. When the operating condition is changed along the polarization curve, the change of physicochemical variables in the membrane electrode assembly is studied. In particular, the over-potential diagram presents the usage of the electrochemical energy at each layer of the membrane electrode assembly. Humidity in supplying gases is one of the most important factors to consider for improving the performance of PEMFE. Both high and low humidity conditions can result in a deteriorating cell performance. The effect of humidity on the cell performance is studied in the chapter 2. First, a numerical model based on computational fluid dynamics is developed. Second, the cell performances are simulated, when the relative humidity is changed from 0% to 100% in the anode and the cathode channel. The simulation results show how humidity in the reactant gases affects the water content distribution in the membrane, the over-potential at the catalyst layers and eventually the cell performance. In particular, the rapid enhancement in the cell performance caused by self-hydrating membrane is captured by the simulation. Fully humidifying either H2

  4. Higher-order numerical solutions using cubic splines. [for partial differential equations

    Science.gov (United States)

    Rubin, S. G.; Khosla, P. K.

    1975-01-01

    A cubic spline collocation procedure has recently been developed for the numerical solution of partial differential equations. In the present paper, this spline procedure is reformulated so that the accuracy of the second-derivative approximation is improved and parallels that previously obtained for lower derivative terms. The final result is a numerical procedure having overall third-order accuracy for a non-uniform mesh and overall fourth-order accuracy for a uniform mesh. Solutions using both spline procedures, as well as three-point finite difference methods, will be presented for several model problems.-

  5. Rapid manufacturing facilitated customisation

    OpenAIRE

    Tuck, Christopher John; Hague, Richard; Ruffo, Massimiliano; Ransley, Michelle; Adams, Paul Russell

    2008-01-01

    Abstract This paper describes the production of body-fitting customised seat profiles utilising the following digital methods: three dimensional laser scanning, reverse engineering and Rapid Manufacturing (RM). The seat profiles have been manufactured in order to influence the comfort characteristics of an existing ejector seat manufactured by Martin Baker Aircraft Ltd. The seat, known as Navy Aircrew Common Ejection Seat (NACES), was originally designed with a generic profile. ...

  6. Rapid Detection of Pathogens

    Energy Technology Data Exchange (ETDEWEB)

    David Perlin

    2005-08-14

    Pathogen identification is a crucial first defense against bioterrorism. A major emphasis of our national biodefense strategy is to establish fast, accurate and sensitive assays for diagnosis of infectious diseases agents. Such assays will ensure early and appropriate treatment of infected patients. Rapid diagnostics can also support infection control measures, which monitor and limit the spread of infectious diseases agents. Many select agents are highly transmissible in the early stages of disease, and it is critical to identify infected patients and limit the risk to the remainder of the population and to stem potential panic in the general population. Nucleic acid-based molecular approaches for identification overcome many of the deficiencies associated with conventional culture methods by exploiting both large- and small-scale genomic differences between organisms. PCR-based amplification of highly conserved ribosomal RNA (rRNA) genes, intergenic sequences, and specific toxin genes is currently the most reliable approach for bacterial, fungal and many viral pathogenic agents. When combined with fluorescence-based oligonucleotide detection systems, this approach provides real-time, quantitative, high fidelity analysis capable of single nucleotide allelic discrimination (4). These probe systems offer rapid turn around time (<2 h) and are suitable for high throughput, automated multiplex operations that are critical for clinical diagnostic laboratories. In this pilot program, we have used molecular beacon technology invented at the Public health Research Institute to develop a new generation of molecular probes to rapidly detect important agents of infectious diseases. We have also developed protocols to rapidly extract nucleic acids from a variety of clinical specimen including and blood and tissue to for detection in the molecular assays. This work represented a cooperative research development program between the Kramer-Tyagi/Perlin labs on probe development

  7. Tiber Personal Rapid Transit

    Directory of Open Access Journals (Sweden)

    Diego Carlo D'agostino

    2011-02-01

    Full Text Available The project “Tiber Personal Rapid Transit” have been presented by the author at the Rome City Vision Competition1 2010, an ideas competition, which challenges architects, engineers, designers, students and creatives individuals to develop visionary urban proposals with the intention of stimulating and supporting the contemporary city, in this case Rome. The Tiber PRT proposal tries to answer the competition questions with the definition of a provocative idea: a Personal Rapid transit System on the Tiber river banks. The project is located in the central section of the Tiber river and aims at the renewal of the river banks with the insertion of a Personal Rapid Transit infrastructure. The project area include the riverbank of Tiber from Rome Transtevere RFI station to Piazza del Popolo, an area where main touristic and leisure attractions are located. The intervention area is actually no used by the city users and residents and constitute itself a strong barrier in the heart of the historic city.

  8. [The systematic selection of speech audiometric procedures].

    Science.gov (United States)

    Steffens, T

    2017-03-01

    The impact of hearing loss on the ability to participate in verbal communication can be directly quantified through the use of speech audiometry. Advances in technology and the associated reduction in background noise interference for hearing aids have allowed the reproduction of very complex acoustic environments, analogous to those in which conversations occur in daily life. These capabilities have led to the creation of numerous advanced speech audiometry measures, test procedures and environments, far beyond the presentation of isolated words in an otherwise noise-free testing booth. The aim of this study was to develop a set of systematic criteria for the appropriate selection of speech audiometric material, which are presented in this article in relationship to the most widely used test procedures. Before an appropriate speech test can be selected from the numerous procedures available, the precise aims of the evaluation should be basically defined. Specific test characteristics, such as validity, objectivity, reliability and sensitivity are important for the selection of the correct test for the specific goals. A concrete understanding of the goals of the evaluation as well as of specific test criteria play a crucial role in the selection of speech audiometry testing procedures.

  9. Numerical modeling of partial discharges parameters

    Directory of Open Access Journals (Sweden)

    Kartalović Nenad M.

    2016-01-01

    Full Text Available In recent testing of the partial discharges or the use for the diagnosis of insulation condition of high voltage generators, transformers, cables and high voltage equipment develops rapidly. It is a result of the development of electronics, as well as, the development of knowledge about the processes of partial discharges. The aim of this paper is to contribute the better understanding of this phenomenon of partial discharges by consideration of the relevant physical processes in isolation materials and isolation systems. Prebreakdown considers specific processes, and development processes at the local level and their impact on specific isolation material. This approach to the phenomenon of partial discharges needed to allow better take into account relevant discharge parameters as well as better numerical model of partial discharges.

  10. Rapid parapatric speciation on holey adaptive landscapes

    CERN Document Server

    Gavrilets, S; Vose, M D; Gavrilets, Sergey; Li, Hai; Vose, Michael D.

    1998-01-01

    A classical view of speciation is that reproductive isolation arises as a by-product of genetic divergence. Here, individual-based simulations are used to evaluate whether the mechanisms implied by this view may result in rapid speciation if the only source of genetic divergence are mutation and random genetic drift. Distinctive features of the simulations are the consideration of the complete process of speciation (from initiation until completion), and of a large number of loci, which was only one order of magnitude smaller than that of bacteria. It is demonstrated that rapid speciation on the time scale of hundreds of generations is plausible without the need for extreme founder events, complete geographic isolation, the existence of distinct adaptive peaks or selection for local adaptation. The plausibility of speciation is enhanced by population subdivision. Simultaneous emergence of more than two new species from a subdivided population is highly probable. Numerical examples relevant to the theory of ce...

  11. Numerical Extraction of Distributions of Space-charge and Polarization from Laser Intensity Modulation Method

    OpenAIRE

    Tuncer, Enis; Lang, Sidney B.

    2004-01-01

    The Fredholm integral equation of the laser intensity modulation method is solved with the application of the Monte Carlo technique and a least-squares solver. The numerical procedure is tested on simulated data.

  12. Mastectomy -- The Surgical Procedure

    Science.gov (United States)

    ... Factors That Affect Prognosis And Treatment Breast Reconstruction Mastectomy - The Procedure A mastectomy is performed under general ... prognosis. Learn more about assessing axillary lymph nodes . Mastectomy with and without breast reconstruction Breast reconstruction Some ...

  13. Special Blood Donation Procedures

    Science.gov (United States)

    ... Blood Products Special Blood Donation Procedures Precautions and Adverse Reactions During Blood Transfusion (See Overview of Blood Transfusion .) Plateletpheresis (platelet donation) In plateletpheresis, a donor gives only platelets rather than whole blood. Whole ...

  14. Numerical modeling of economic uncertainty

    DEFF Research Database (Denmark)

    Schjær-Jacobsen, Hans

    2007-01-01

    Representation and modeling of economic uncertainty is addressed by different modeling methods, namely stochastic variables and probabilities, interval analysis, and fuzzy numbers, in particular triple estimates. Focusing on discounted cash flow analysis numerical results are presented, comparisons...

  15. BCJ numerators from reduced Pfaffian

    Energy Technology Data Exchange (ETDEWEB)

    Du, Yi-Jian [Center for Theoretical Physics, School of Physics and Technology, Wuhan University,No. 299 Bayi Road, Wuhan 430072 (China); Teng, Fei [Department of Physics and Astronomy, University of Utah,115 South 1400 East, Salt Lake City, UT 84112 (United States)

    2017-04-07

    By expanding the reduced Pfaffian in the tree level Cachazo-He-Yuan (CHY) integrands for Yang-Mills (YM) and nonlinear sigma model (NLSM), we can get the Bern-Carrasco-Johansson (BCJ) numerators in Del Duca-Dixon-Maltoni (DDM) form for arbitrary number of particles in any spacetime dimensions. In this work, we give a set of very straightforward graphic rules based on spanning trees for a direct evaluation of the BCJ numerators for YM and NLSM. Such rules can be derived from the Laplace expansion of the corresponding reduced Pfaffian. For YM, the each one of the (n−2)! DDM form BCJ numerators contains exactly (n−1)! terms, corresponding to the increasing trees with respect to the color order. For NLSM, the number of nonzero numerators is at most (n−2)!−(n−3)!, less than those of several previous constructions.

  16. Rapid prototyping tools

    OpenAIRE

    Birkeland, Petter I

    2016-01-01

    This paper is the description of the method and result of the master project of Petter Ildgruben at the Department of Engineering Design and Materials (IPM) at the Norwegian University of Science and Technology (NTNU) in the spring of 2016. The goal of this master s thesis has been to explore the barriers that novel users face in makerspaces, specifically when interacting with the 3D printer, the laser cutter and the Computer Numerical Control (CNC) mill and how to overcome them. The first...

  17. A conjecture on numeral systems

    OpenAIRE

    Nour, Karim

    1997-01-01

    International audience; A numeral system is an infinite sequence of different closed normal $\\lambda$-terms intended to code the integers in $\\lambda$-calculus. H. Barendregt has shown that if we can represent, for a numeral system, the functions : Successor, Predecessor, and Zero Test, then all total recursive functions can be represented. In this paper we prove the independancy of these particular three functions. We give at the end a conjecture on the number of unary functions necessary to...

  18. Numerical Analysis of Multiscale Computations

    CERN Document Server

    Engquist, Björn; Tsai, Yen-Hsi R

    2012-01-01

    This book is a snapshot of current research in multiscale modeling, computations and applications. It covers fundamental mathematical theory, numerical algorithms as well as practical computational advice for analysing single and multiphysics models containing a variety of scales in time and space. Complex fluids, porous media flow and oscillatory dynamical systems are treated in some extra depth, as well as tools like analytical and numerical homogenization, and fast multipole method.

  19. Numerical approaches to system of fractional partial differential equations

    Directory of Open Access Journals (Sweden)

    H. F. Ahmed

    2017-04-01

    Full Text Available In this paper, by introducing the fractional derivative in sense of Caputo, the Laplace- variational iteration method (LVIM and the Laplace-Adomian decomposition method (LADM are directly extended to study the linear and nonlinear systems of fractional partial differential equations, as a result the approximated numerical solutions are acquired in the form of rapidly convergent series with easily computable components. Numerical results show that the two approaches are easy to implement and accurate when are applied. Compassions are made between the two methods and exact solutions. Figures are used to show the efficiency as well as the accuracy of the achieved approximated results.

  20. Numerical Simulation of Duplex Steel Multipass Welding

    Directory of Open Access Journals (Sweden)

    Giętka T.

    2016-12-01

    Full Text Available Analyses based on FEM calculations have significantly changed the possibilities of determining welding strains and stresses at early stages of product design and welding technology development. Such an approach to design enables obtaining significant savings in production preparation and post-weld deformation corrections and is also important for utility properties of welded joints obtained. As a result, it is possible to make changes to a simulated process before introducing them into real production as well as to test various variants of a given solution. Numerical simulations require the combination of problems of thermal, mechanical and metallurgical analysis. The study presented involved the SYSWELD software-based analysis of GMA welded multipass butt joints made of duplex steel sheets. The analysis of the distribution of stresses and displacements were carried out for typical welding procedure as during real welding tests.

  1. Rapidly variable relatvistic absorption

    Science.gov (United States)

    Parker, M.; Pinto, C.; Fabian, A.; Lohfink, A.; Buisson, D.; Alston, W.; Jiang, J.

    2017-10-01

    I will present results from the 1.5Ms XMM-Newton observing campaign on the most X-ray variable AGN, IRAS 13224-3809. We find a series of nine absorption lines with a velocity of 0.24c from an ultra-fast outflow. For the first time, we are able to see extremely rapid variability of the UFO features, and can link this to the X-ray variability from the inner accretion disk. We find a clear flux dependence of the outflow features, suggesting that the wind is ionized by increasing X-ray emission.

  2. Rapid prototype and test

    Energy Technology Data Exchange (ETDEWEB)

    Gregory, D.L.; Hansche, B.D.

    1996-06-01

    In order to support advanced manufacturing, Sandia has acquired the capability to produce plastic prototypes using stereolithography. Currently, these prototypes are used mainly to verify part geometry and ``fit and form`` checks. This project investigates methods for rapidly testing these plastic prototypes, and inferring from prototype test data actual metal part performance and behavior. Performances examined include static load/stress response, and structural dynamic (modal) and vibration behavior. The integration of advanced non-contacting measurement techniques including scanning laser velocimetry, laser holography, and thermoelasticity into testing of these prototypes is described. Photoelastic properties of the epoxy prototypes to reveal full field stress/strain fields are also explored.

  3. Right-Rapid-Rough

    Science.gov (United States)

    Lawrence, Craig

    2003-01-01

    IDEO (pronounced 'eye-dee-oh') is an international design, engineering, and innovation firm that has developed thousands of products and services for clients across a wide range of industries. Its process and culture attracted the attention of academics, businesses, and journalists around the world, and are the subject of a bestselling book, The Art of Innovation by Tom Kelley. One of the keys to IDEO's success is its use of prototyping as a tool for rapid innovation. This story covers some of IDEO's projects, and gives reasons for why they were successful.

  4. Projected discrete ordinates methods for numerical transport problems

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, E.W.

    1985-01-01

    A class of Projected Discrete-Ordinates (PDO) methods is described for obtaining iterative solutions of discrete-ordinates problems with convergence rates comparable to those observed using Diffusion Synthetic Acceleration (DSA). The spatially discretized PDO solutions are generally not equal to the DSA solutions, but unlike DSA, which requires great care in the use of spatial discretizations to preserve stability, the PDO solutions remain stable and rapidly convergent with essentially arbitrary spatial discretizations. Numerical results are presented which illustrate the rapid convergence and the accuracy of solutions obtained using PDO methods with commonplace differencing methods.

  5. Rapid mineralocorticoid receptor trafficking.

    Science.gov (United States)

    Gekle, M; Bretschneider, M; Meinel, S; Ruhs, S; Grossmann, C

    2014-03-01

    The mineralocorticoid receptor (MR) is a ligand-dependent transcription factor that physiologically regulates water-electrolyte homeostasis and controls blood pressure. The MR can also elicit inflammatory and remodeling processes in the cardiovascular system and the kidneys, which require the presence of additional pathological factors like for example nitrosative stress. However, the underlying molecular mechanism(s) for pathophysiological MR effects remain(s) elusive. The inactive MR is located in the cytosol associated with chaperone molecules including HSP90. After ligand binding, the MR monomer rapidly translocates into the nucleus while still being associated to HSP90 and after dissociation from HSP90 binds to hormone-response-elements called glucocorticoid response elements (GREs) as a dimer. There are indications that rapid MR trafficking is modulated in the presence of high salt, oxidative or nitrosative stress, hypothetically by induction or posttranslational modifications. Additionally, glucocorticoids and the enzyme 11beta hydroxysteroid dehydrogenase may also influence MR activation. Because MR trafficking and its modulation by micro-milieu factors influence MR cellular localization, it is not only relevant for genomic but also for nongenomic MR effects. Copyright © 2013 Elsevier Inc. All rights reserved.

  6. Rapid response manufacturing (RRM)

    Energy Technology Data Exchange (ETDEWEB)

    Cain, W.D. [Lockheed Martin Energy Systems, Inc., Oak Ridge, TN (United States); Waddell, W.L. [National Centers for Manufacturing Sciences, Ann Arbor, MI (United States)

    1997-02-18

    US industry is fighting to maintain its competitive edge in the global market place. Today markets fluctuate rapidly. Companies, to survive, have to be able to respond with quick-to-market, improved, high quality, cost efficient products. The way products are developed and brought to market can be improved and made more efficient through the proper incorporation of emerging technologies. The RRM project was established to leverage the expertise and resources of US private industries and federal agencies to develop, integrate, and deploy new technologies that meet critical needs for effective product realization. The RRM program addressed a needed change in the US Manufacturing infrastructure that will ensure US competitiveness in world market typified by mass customization. This project provided the effort needed to define, develop and establish a customizable infrastructure for rapid response product development design and manufacturing. A major project achievement was the development of a broad-based framework for automating and integrating the product and process design and manufacturing activities involved with machined parts. This was accomplished by coordinating and extending the application of feature-based product modeling, knowledge-based systems, integrated data management, and direct manufacturing technologies in a cooperative integrated computing environment. Key technological advancements include a product model that integrates product and process data in a consistent, minimally redundant manner, an advanced computer-aided engineering environment, knowledge-based software aids for design and process planning, and new production technologies to make products directly from design application software.

  7. Rapid estimation of organic nitrogen in oil shale wastewaters

    Energy Technology Data Exchange (ETDEWEB)

    Jones, B.M.; Harris, G.J.; Daughton, C.G.

    1984-03-01

    Many of the characteristics of oil shale process wastewaters (e.g., malodors, color, and resistance to biotreatment) are imparted by numerous nitrogen heterocycles and aromatic amines. For the frequent performance assessment of waste treatment procsses designed to remove these nitrogenous organic compounds, a rapid and colligative measurement of organic nitrogen is essential.

  8. Rapid micropropagation of Boesenbergia rotunda (L.) Mansf. Kulturpfl.

    African Journals Online (AJOL)

    Rapid micropropagation of Boesenbergia rotunda (L.) Mansf. Kulturpfl. (a valuable medicinal plant) from shoot bud explants. NA Yusuf, MMS Annuar, N Khalid. Abstract. A successful protocol was developed for mass propagation of Boesenbergia rotunda (L.) Mansf. Kulturpfl., an important medicinal plant. Numerous shoots ...

  9. An Energy Based Numerical Approach to Phase Change Problems

    DEFF Research Database (Denmark)

    Hauggaard-Nielsen, Anders Boe; Damkilde, Lars; Krenk, Steen

    1996-01-01

    Phase change problems, occurring e.g. in melting, casting and freezing processes, are often characterized by a very narrow transition zone with very lareg changes in heat capacity and conductivity. This leads to problems in numerical procedures, where the transition zone propagates through a mesh...... in the mid-point of the current time step and full energy balance is restored in each iteration by adjusting the local temperature. Examples demonstrate improved accuracy, a reduction of the numerical disturbances introduced by the passage of the transition zone and a smaller number of timesteps needed...

  10. Numerical simulation of asphalt mixtures fracture using continuum models

    Science.gov (United States)

    Szydłowski, Cezary; Górski, Jarosław; Stienss, Marcin; Smakosz, Łukasz

    2018-01-01

    The paper considers numerical models of fracture processes of semi-circular asphalt mixture specimens subjected to three-point bending. Parameter calibration of the asphalt mixture constitutive models requires advanced, complex experimental test procedures. The highly non-homogeneous material is numerically modelled by a quasi-continuum model. The computational parameters are averaged data of the components, i.e. asphalt, aggregate and the air voids composing the material. The model directly captures random nature of material parameters and aggregate distribution in specimens. Initial results of the analysis are presented here.

  11. Procedural sedation analgesia

    Directory of Open Access Journals (Sweden)

    Sheta Saad

    2010-01-01

    Full Text Available The number of noninvasive and minimally invasive procedures performed outside of the operating room has grown exponentially over the last several decades. Sedation, analgesia, or both may be needed for many of these interventional or diagnostic procedures. Individualized care is important when determining if a patient requires procedural sedation analgesia (PSA. The patient might need an anti-anxiety drug, pain medicine, immobilization, simple reassurance, or a combination of these interventions. The goals of PSA in four different multidisciplinary practices namely; emergency, dentistry, radiology and gastrointestinal endoscopy are discussed in this review article. Some procedures are painful, others painless. Therefore, goals of PSA vary widely. Sedation management can range from minimal sedation, to the extent of minimal anesthesia. Procedural sedation in emergency department (ED usually requires combinations of multiple agents to reach desired effects of analgesia plus anxiolysis. However, in dental practice, moderate sedation analgesia (known to the dentists as conscious sedation is usually what is required. It is usually most effective with the combined use of local anesthesia. The mainstay of success for painless imaging is absolute immobility. Immobility can be achieved by deep sedation or minimal anesthesia. On the other hand, moderate sedation, deep sedation, minimal anesthesia and conventional general anesthesia can be all utilized for management of gastrointestinal endoscopy.

  12. Mobile Energy Laboratory Procedures

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, P.R.; Batishko, C.R.; Dittmer, A.L.; Hadley, D.L.; Stoops, J.L.

    1993-09-01

    Pacific Northwest Laboratory (PNL) has been tasked to plan and implement a framework for measuring and analyzing the efficiency of on-site energy conversion, distribution, and end-use application on federal facilities as part of its overall technical support to the US Department of Energy (DOE) Federal Energy Management Program (FEMP). The Mobile Energy Laboratory (MEL) Procedures establish guidelines for specific activities performed by PNL staff. PNL provided sophisticated energy monitoring, auditing, and analysis equipment for on-site evaluation of energy use efficiency. Specially trained engineers and technicians were provided to conduct tests in a safe and efficient manner with the assistance of host facility staff and contractors. Reports were produced to describe test procedures, results, and suggested courses of action. These reports may be used to justify changes in operating procedures, maintenance efforts, system designs, or energy-using equipment. The MEL capabilities can subsequently be used to assess the results of energy conservation projects. These procedures recognize the need for centralized NM administration, test procedure development, operator training, and technical oversight. This need is evidenced by increasing requests fbr MEL use and the economies available by having trained, full-time MEL operators and near continuous MEL operation. DOE will assign new equipment and upgrade existing equipment as new capabilities are developed. The equipment and trained technicians will be made available to federal agencies that provide funding for the direct costs associated with MEL use.

  13. Rapid induction of false memory for pictures.

    Science.gov (United States)

    Weinstein, Yana; Shanks, David R

    2010-07-01

    Recognition of pictures is typically extremely accurate, and it is thus unclear whether the reconstructive nature of memory can yield substantial false recognition of highly individuated stimuli. A procedure for the rapid induction of false memories for distinctive colour photographs is proposed. Participants studied a set of object pictures followed by a list of words naming those objects, but embedded in the list were names of unseen objects. When subsequently shown full colour pictures of these unseen objects, participants consistently claimed that they had seen them, while discriminating with high accuracy between studied pictures and new pictures whose names did not appear in the misleading word list. These false memories can be reported with high confidence as well as the feeling of recollection. This new procedure allows the investigation of factors that influence false memory reports with ecologically valid stimuli and of the similarities and differences between true and false memories.

  14. Rapid calculation of the compression wave generated by a train entering a tunnel with a vented hood: Short hoods

    Science.gov (United States)

    Howe, M. S.; Winslow, A.; Iida, M.; Fukuda, T.

    2008-03-01

    A numerical procedure for the rapid prediction of the compression wave generated by a high-speed train entering a tunnel was presented and validated by Howe et al. [Rapid calculation of the compression wave generated by a train entering a tunnel with a vented hood, Journal of Sound and Vibration 297 (2006) 267-292]. The method was devised to deal principally with compression wave generation in long hoods typically of length ˜10 times the tunnel height and 'vented' by means of a series of windows distributed along the hood walls. Hoods of this kind will be needed to control wave generation by newer trains operating at speeds U exceeding about 350 km/h. In this paper experimental results are presented and compared with predictions in order to extend the range of applicability of the numerical method of Howe et al. (2006) to include short hoods with lengths as small as just twice the tunnel height (the situation for most hoods currently deployed on the Japanese Shinkansen) and for U as large as 400 km/h.

  15. A numerical study of unstable Hele-Shaw flow

    DEFF Research Database (Denmark)

    Hansen, Erik Bent; Rasmussen, Henning

    1999-01-01

    A numerical procedure which is based on an integral equation for the normal velocity at the interface is developed for the unstable flow with surface tension in a Hele-Shaw cell. The procedure has been validated by comparing solutions obtained by it with published results. It has also been applied...... to a study of the effect of small changes in the initial data on the later profiles and it was found that even very small differences can lead to large differences in the profiles at later times. (C) 1999 Elsevier Science Ltd. All rights reserved....

  16. Experimental and numerical research on forging with torsion

    Science.gov (United States)

    Petrov, Mikhail A.; Subich, Vadim N.; Petrov, Pavel A.

    2017-10-01

    Increasing the efficiency of the technological operations of blank production is closely related to the computer-aided technologies (CAx). On the one hand, the practical result represents reality exactly. On the other hand, the development procedure of new process development demands unrestricted resources, which are limited on the SMEs. The tools of CAx were successfully applied for development of new process of forging with torsion and result analysis as well. It was shown, that the theoretical calculations find the confirmation both in praxis and during numerical simulation. The mostly used constructional materials were under study. The torque angles were stated. The simulated results were evaluated by experimental procedure.

  17. Efficient approximation of random fields for numerical applications

    KAUST Repository

    Harbrecht, Helmut

    2015-01-07

    We consider the rapid computation of separable expansions for the approximation of random fields. We compare approaches based on techniques from the approximation of non-local operators on the one hand and based on the pivoted Cholesky decomposition on the other hand. We provide an a-posteriori error estimate for the pivoted Cholesky decomposition in terms of the trace. Numerical examples validate and quantify the considered methods.

  18. Editing of EIA coded, numerically controlled, machine tool tapes

    Science.gov (United States)

    Weiner, J. M.

    1975-01-01

    Editing of numerically controlled (N/C) machine tool tapes (8-level paper tape) using an interactive graphic display processor is described. A rapid technique required for correcting production errors in N/C tapes was developed using the interactive text editor on the IMLAC PDS-ID graphic display system and two special programs resident on disk. The correction technique and special programs for processing N/C tapes coded to EIA specifications are discussed.

  19. Procedure and Program Examples

    Science.gov (United States)

    Britz, Dieter

    Here some modules, procedures and whole programs are described, that may be useful to the reader, as they have been, to the author. They are all in Fortran 90/95 and start with a generally useful module, that will be used in most procedures and programs in the examples, and another module useful for programs using a Rosenbrock variant. The source texts (except for the two modules) are not reproduced here, but can be downloaded from the web site www.springerlink.com/openurl.asp?genre=issue &issn=1616-6361&volume=666 (the two lines form one contiguous URL!).

  20. Objective calibration of numerical weather prediction models

    Science.gov (United States)

    Voudouri, A.; Khain, P.; Carmona, I.; Bellprat, O.; Grazzini, F.; Avgoustoglou, E.; Bettems, J. M.; Kaufmann, P.

    2017-07-01

    Numerical weather prediction (NWP) and climate models use parameterization schemes for physical processes, which often include free or poorly confined parameters. Model developers normally calibrate the values of these parameters subjectively to improve the agreement of forecasts with available observations, a procedure referred as expert tuning. A practicable objective multi-variate calibration method build on a quadratic meta-model (MM), that has been applied for a regional climate model (RCM) has shown to be at least as good as expert tuning. Based on these results, an approach to implement the methodology to an NWP model is presented in this study. Challenges in transferring the methodology from RCM to NWP are not only restricted to the use of higher resolution and different time scales. The sensitivity of the NWP model quality with respect to the model parameter space has to be clarified, as well as optimize the overall procedure, in terms of required amount of computing resources for the calibration of an NWP model. Three free model parameters affecting mainly turbulence parameterization schemes were originally selected with respect to their influence on the variables associated to daily forecasts such as daily minimum and maximum 2 m temperature as well as 24 h accumulated precipitation. Preliminary results indicate that it is both affordable in terms of computer resources and meaningful in terms of improved forecast quality. In addition, the proposed methodology has the advantage of being a replicable procedure that can be applied when an updated model version is launched and/or customize the same model implementation over different climatological areas.

  1. Numerical Package in Computer Supported Numeric Analysis Teaching

    Science.gov (United States)

    Tezer, Murat

    2007-01-01

    At universities in the faculties of Engineering, Sciences, Business and Economics together with higher education in Computing, it is stated that because of the difficulty, calculators and computers can be used in Numerical Analysis (NA). In this study, the learning computer supported NA will be discussed together with important usage of the…

  2. numerical and numerical and experimental modeling of the static

    African Journals Online (AJOL)

    eobe

    recommendation for subsequent experiments and analysis of these types of structural elements. In this paper a report of numerical and experimental modeling of the static response of thin-walled reinforced concrete box girder bridges is given. The work is executed to verify the validity of a software developed by the authors ...

  3. Numerical models for differential problems

    CERN Document Server

    Quarteroni, Alfio

    2017-01-01

    In this text, we introduce the basic concepts for the numerical modelling of partial differential equations. We consider the classical elliptic, parabolic and hyperbolic linear equations, but also the diffusion, transport, and Navier-Stokes equations, as well as equations representing conservation laws, saddle-point problems and optimal control problems. Furthermore, we provide numerous physical examples which underline such equations. We then analyze numerical solution methods based on finite elements, finite differences, finite volumes, spectral methods and domain decomposition methods, and reduced basis methods. In particular, we discuss the algorithmic and computer implementation aspects and provide a number of easy-to-use programs. The text does not require any previous advanced mathematical knowledge of partial differential equations: the absolutely essential concepts are reported in a preliminary chapter. It is therefore suitable for students of bachelor and master courses in scientific disciplines, an...

  4. Numerical models for differential problems

    CERN Document Server

    Quarteroni, Alfio

    2014-01-01

    In this text, we introduce the basic concepts for the numerical modelling of partial differential equations. We consider the classical elliptic, parabolic and hyperbolic linear equations, but also the diffusion, transport, and Navier-Stokes equations, as well as equations representing conservation laws, saddle-point problems and optimal control problems. Furthermore, we provide numerous physical examples which underline such equations. We then analyze numerical solution methods based on finite elements, finite differences, finite volumes, spectral methods and domain decomposition methods, and reduced basis methods. In particular, we discuss the algorithmic and computer implementation aspects and provide a number of easy-to-use programs. The text does not require any previous advanced mathematical knowledge of partial differential equations: the absolutely essential concepts are reported in a preliminary chapter. It is therefore suitable for students of bachelor and master courses in scientific disciplines, an...

  5. Combining Narrative and Numerical Simulation

    DEFF Research Database (Denmark)

    Hansen, Mette Sanne; Ladeby, Klaes Rohde; Rasmussen, Lauge Baungaard

    2011-01-01

    Strategic simulation is the combination of narrative and numerical simulation and can be used as a tool to support strategic decision making by providing different scenarios in combination with computer modelling. The core of the combined simulation approach (CSA) is to make it possible for decis......Strategic simulation is the combination of narrative and numerical simulation and can be used as a tool to support strategic decision making by providing different scenarios in combination with computer modelling. The core of the combined simulation approach (CSA) is to make it possible...... to the decision making in operations and production management by providing new insights into modelling and simulation based on the combined narrative and numerical simulation approach as a tool for strategy making. The research question asks, “How can the CSA be applied in a practical context to support strategy...

  6. Numerical methods in multibody dynamics

    CERN Document Server

    Eich-Soellner, Edda

    1998-01-01

    Today computers play an important role in the development of complex mechanical systems, such as cars, railway vehicles or machines. Efficient simulation of these systems is only possible when based on methods that explore the strong link between numerics and computational mechanics. This book gives insight into modern techniques of numerical mathematics in the light of an interesting field of applications: multibody dynamics. The important interaction between modeling and solution techniques is demonstrated by using a simplified multibody model of a truck. Different versions of this mechanical model illustrate all key concepts in static and dynamic analysis as well as in parameter identification. The book focuses in particular on constrained mechanical systems. Their formulation in terms of differential-algebraic equations is the backbone of nearly all chapters. The book is written for students and teachers in numerical analysis and mechanical engineering as well as for engineers in industrial research labor...

  7. Numerical cognition: Adding it up.

    Science.gov (United States)

    LeFevre, Jo-Anne

    2016-03-01

    In this article, I provide a historical overview of the field of numerical cognition. I first situate the evolution and development of this field in the more general context of the cognitive revolution, which started in the mid-1950s. I then discuss the genesis of numerical cognition from 6 areas: psychophysics, information processing, neuropsychology, mathematics education, psychometrics, and cognitive development. This history is personal: I discuss some of my own work over the last 30 years and describe how each of the authors of the articles in this collection originally connected with the field. One important goal of the article is to highlight the major findings, both for experts and for those who are less familiar with research on numerical processing. In sum, I sketch a context within which to appreciate the neural, computational, and behavioural work that the other 4 authors summarise in their articles in this special section. (c) 2016 APA, all rights reserved).

  8. A rapid ultrasound particle agglutination method for HIV antibody detection: Comparison with conventional rapid HIV tests.

    Science.gov (United States)

    Bystryak, Simon; Ossina, Natalya

    2017-11-01

    We present the results of the feasibility and preliminary studies on analytical performance of a rapid test for detection of human immunodeficiency virus (HIV) antibodies in human serum or plasma that is an important advance in detecting HIV infection. Current methods for rapid testing of antibodies against HIV are qualitative and exhibit poor sensitivity (limit of detection). In this paper, we describe an ultrasound particle agglutination (UPA) method that leads to a significant increase of the sensitivity of conventional latex agglutination tests for HIV antibody detection in human serum or plasma. The UPA method is based on the use of: 1) a dual mode ultrasound, wherein a first single-frequency mode is used to accelerate the latex agglutination process, and then a second swept-frequency mode of sonication is used to disintegrate non-specifically bound aggregates; and 2) a numerical assessment of results of the agglutination process. The numerical assessment is carried out by optical detection and analysis of moving patterns in the resonator cell during the swept-frequency mode. The single-step UPA method is rapid and more sensitive than the three commercial rapid HIV test kits analyzed in the study: analytical sensitivity of the new UPA method was found to be 510-, 115-, and 80-fold higher than that for Capillus™, Multispot™ and Uni-Gold™ Recombigen HIV antibody rapid test kits, respectively. The newly developed UPA method opens up additional possibilities for detection of a number of clinically significant markers in point-of-care settings. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Numeral Incorporation in Japanese Sign Language

    Science.gov (United States)

    Ktejik, Mish

    2013-01-01

    This article explores the morphological process of numeral incorporation in Japanese Sign Language. Numeral incorporation is defined and the available research on numeral incorporation in signed language is discussed. The numeral signs in Japanese Sign Language are then introduced and followed by an explanation of the numeral morphemes which are…

  10. A Rapid Convergent Low Complexity Interference Alignment Algorithm for Wireless Sensor Networks.

    Science.gov (United States)

    Jiang, Lihui; Wu, Zhilu; Ren, Guanghui; Wang, Gangyi; Zhao, Nan

    2015-07-29

    Interference alignment (IA) is a novel technique that can effectively eliminate the interference and approach the sum capacity of wireless sensor networks (WSNs) when the signal-to-noise ratio (SNR) is high, by casting the desired signal and interference into different signal subspaces. The traditional alternating minimization interference leakage (AMIL) algorithm for IA shows good performance in high SNR regimes, however, the complexity of the AMIL algorithm increases dramatically as the number of users and antennas increases, posing limits to its applications in the practical systems. In this paper, a novel IA algorithm, called directional quartic optimal (DQO) algorithm, is proposed to minimize the interference leakage with rapid convergence and low complexity. The properties of the AMIL algorithm are investigated, and it is discovered that the difference between the two consecutive iteration results of the AMIL algorithm will approximately point to the convergence solution when the precoding and decoding matrices obtained from the intermediate iterations are sufficiently close to their convergence values. Based on this important property, the proposed DQO algorithm employs the line search procedure so that it can converge to the destination directly. In addition, the optimal step size can be determined analytically by optimizing a quartic function. Numerical results show that the proposed DQO algorithm can suppress the interference leakage more rapidly than the traditional AMIL algorithm, and can achieve the same level of sum rate as that of AMIL algorithm with far less iterations and execution time.

  11. Applications of stereolithography for rapid prototyping of biologically compatible chip-based physiometers

    Science.gov (United States)

    Fuad, Nurul Mohd; Zhu, Feng; Kaslin, Jan; Wlodkowic, Donald

    2016-12-01

    Despite the growing demand and numerous applications for the biomedical community, the developments in millifluidic devices for small model organisms are limited compared to other fields of biomicrofluidics. The main reasons for this stagnanation are difficulties in prototyping of millimeter scale and high aspect ratio devices needed for large metazoan organisms. Standard photolithography is in this context a time consuming procedure not easily adapted for fabrication of molds with vertical dimensions above 1 mm. Moreover, photolithography is still largely unattainable to a gross majority of biomedical laboratories willing to pursue custom development of their own chip-based platforms due to costs and need for dedicated clean room facilities. In this work, we present application of high-definition additive manufacturing systems for fabrication of 3D printed moulds used in soft lithography. Combination of 3D printing with PDMS replica molding appears to be an alternative for millifluidic systems that yields rapid and cost effective prototyping pipeline. We investigated the important aspects on both 3D printed moulds and PDMS replicas such as geometric accuracies and surface topology. Our results demonstrated that SLA technologies could be applied for rapid and accurate fabrication of millifluidic devices for trapping of millimetre-sized specimens such as living zebrafish larvae. We applied the new manufacturing method in a proof-of-concept prototype device capable of trapping and immobilizing living zebrafish larvae for recording heart rate variation in cardio-toxicity experiments.

  12. Preschooler test or procedure preparation

    Science.gov (United States)

    Preparing preschoolers for test/procedure; Test/procedure preparation - preschooler ... Preparing children for medical tests can reduce their anxiety. It can also make them less likely to cry and resist the procedure. Research shows that ...

  13. Toddler test or procedure preparation

    Science.gov (United States)

    Preparing toddler for test/procedure; Test/procedure preparation - toddler; Preparing for a medical test or procedure - toddler ... Before the test, know that your child will probably cry. Even if you prepare, your child may feel some discomfort or ...

  14. Best Approximation in Numerical Radius

    OpenAIRE

    Aksoy, Asuman Guven; Lewicki, Grzegorz

    2010-01-01

    Let $X$ be a reflexive Banach space. In this paper we give a necessary and sufficient condition for an operator $T\\in \\mathcal{K}(X)$ to have the best approximation in numerical radius from the convex subset $\\mathcal{U} \\subset \\mathcal{K}(X),$ where $\\mathcal{K}(X)$ denotes the set of all linear, compact operators from $X$ into $X.$ We will also present an application to minimal extensions with respect to the numerical radius. In particular some results on best approximation in norm will be...

  15. Numerical Algorithms for Parallel Computers

    Science.gov (United States)

    1989-08-31

    NUMERICAL ALGORITHMS FOR PARALLEL COMPUTERS 12. PERSONAL AUTHOR(S) Loce M. Adams 13a. TYPE OF REPORT 13b. TIME COVERED 14. DATE OF REPORT (Yea, Month. Day...editions are obsolete. SEC n&"S2IVAQelftS PAGE 90 01 11 131 . . AP06w.TR. 8 9 -l1N5 Numerical Algorithms for Parallel Computers Loyce M. Adams Department of...Conference on Applied Linear Algebra, Loyce Adams presented minisym- posium talk Preconditioners on Parallel Computers , Madison, WI., May 1988. Third

  16. Numeric invariants from multidimensional persistence

    Energy Technology Data Exchange (ETDEWEB)

    Skryzalin, Jacek [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Carlsson, Gunnar [Stanford Univ., Stanford, CA (United States)

    2017-05-19

    In this paper, we analyze the space of multidimensional persistence modules from the perspectives of algebraic geometry. We first build a moduli space of a certain subclass of easily analyzed multidimensional persistence modules, which we construct specifically to capture much of the information which can be gained by using multidimensional persistence over one-dimensional persistence. We argue that the global sections of this space provide interesting numeric invariants when evaluated against our subclass of multidimensional persistence modules. Lastly, we extend these global sections to the space of all multidimensional persistence modules and discuss how the resulting numeric invariants might be used to study data.

  17. Matlab programming for numerical analysis

    CERN Document Server

    Lopez, Cesar

    2014-01-01

    MATLAB is a high-level language and environment for numerical computation, visualization, and programming. Using MATLAB, you can analyze data, develop algorithms, and create models and applications. The language, tools, and built-in math functions enable you to explore multiple approaches and reach a solution faster than with spreadsheets or traditional programming languages, such as C/C++ or Java. Programming MATLAB for Numerical Analysis introduces you to the MATLAB language with practical hands-on instructions and results, allowing you to quickly achieve your goals. You will first become

  18. CLPX NOAA FSL Rapid Update Cycle 20 km (RUC-20) Dataset, Version 1

    Data.gov (United States)

    National Aeronautics and Space Administration — The Rapid Update Cycle analysis/model system at a 20-km horizontal resolution (RUC20) provides short-range numerical weather guidance for general forecasting, as...

  19. CLPX NOAA FSL Rapid Update Cycle 20 km (RUC-20) Dataset

    Data.gov (United States)

    National Aeronautics and Space Administration — The Rapid Update Cycle analysis/model system at a 20-km horizontal resolution (RUC20) provides short-range numerical weather guidance for general forecasting, as...

  20. The TOMAX-procedure

    NARCIS (Netherlands)

    Overgoor, M.L.E.

    2015-01-01

    Most patients with a low spinal lesion (LSL) have intact erectile function but no penile sensation, which can lead to frustration. To tackle this problem, we designed TOMAX, TOMAXimize sensation, sexuality and quality of life, a surgical procedure in which a functional "groin” nerve is connected to

  1. Formalizing physical security procedures

    NARCIS (Netherlands)

    Meadows, C.; Pavlovic, Dusko

    Although the problems of physical security emerged more than 10,000 years before the problems of computer security, no formal methods have been developed for them, and the solutions have been evolving slowly, mostly through social procedures. But as the traffic on physical and social networks is now

  2. 3. Procedures and Recursion

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 6. Algorithms Procedures and Recursion. R K Shyamasundar. Series Article Volume 1 ... Author Affiliations. R K Shyamasundar1. Computer Science Group, Tata Institute of Fundamental Research, Homi Bhabha Road Mumbai 400 005, India.

  3. Colorimetry and SERS dual-mode detection of telomerase activity: combining rapid screening with high sensitivity.

    Science.gov (United States)

    Zong, Shenfei; Wang, Zhuyuan; Chen, Hui; Hu, Guohua; Liu, Min; Chen, Peng; Cui, Yiping

    2014-01-01

    As an important biomarker and therapeutic target, telomerase has attracted considerable attention concerning its detection and monitoring. Here, we present a colorimetry and surface enhanced Raman scattering (SERS) dual-mode telomerase activity detection method, which has several distinctive advantages. First, colorimetric functionality allows rapid preliminary discrimination of telomerase activity by the naked eye. Second, the employment of SERS technique results in greatly improved detection sensitivity. Third, the combination of colorimetry and SERS into one detection system can ensure highly efficacious and sensitive screening of numerous samples. Besides, the avoidance of polymerase chain reaction (PCR) procedures further guarantees fine reliability and simplicity. Generally, the presented method is realized by an "elongate and capture" procedure. To be specific, gold nanoparticles modified with Raman molecules and telomeric repeat complementary oligonucleotide are employed as the colorimetric-SERS bifunctional reporting nanotag, while magnetic nanoparticles functionalized with telomerase substrate oligonucleotide are used as the capturing substrate. Telomerase can synthesize and elongate telomeric repeats onto the capturing substrate. The elongated telomeric repeats subsequently facilitate capturing of the reporting nanotag via hybridization between telomeric repeat and its complementary strand. The captured nanotags can cause a significant difference in the color and SERS intensity of the magnetically separated sediments. Thus both the color and SERS can be used as indicators of the telomerase activity. With fast screening ability and outstanding sensitivity, we anticipate that this method would greatly promote practical application of telomerase-based early-stage cancer diagnosis.

  4. Numerical analysis of fragmentation mechanisms in vapor explosions

    Energy Technology Data Exchange (ETDEWEB)

    Koshizuka, Seiichi; Ikeda, Hirokazu; Oka, Yoshiaki [Tokyo Univ., Tokai, Ibaraki (Japan). Nuclear Engineering Research Lab.

    1998-01-01

    Fragmentation of molten metal is the key process in vapor explosions. However this process is so rapid that the mechanisms have not been clarified yet in the experimental studies. Besides, numerical simulation is difficult because we have to analyze water, steam and molten metal simultaneously with evaporation and fragmentation. The authors have been developing a new numerical method, the Moving Particle Semi-implicit (MPS) method, based on moving particles and their interactions. Grids are not necessary. Incompressible flows with fragmentation on free surfaces have been calculated successfully using the MPS method. In the present study numerical simulation of the fragmentation processes using the MPS method is carried out to investigate the mechanisms. A numerical model to calculate evaporation from water to steam is developed. In this model, new particles are generated on water-steam interfaces. Effect of evaporation is also investigated. Growth of the filament is not accelerated when the normal evaporation is considered. This is because the normal evaporation needs a longer time than the moment of the jet impingement, though the filament growth is decided in this moment. Next, rapid evaporation based on spontaneous nucleation is considered. The filament growth is markedly accelerated. This result is consistent with the experimental fact that the spontaneous nucleation temperature is a necessary condition of small-scale vapor explosions. (J.P.N.)

  5. Juveniles in criminal procedure

    Directory of Open Access Journals (Sweden)

    Lukić Tatjana

    2012-01-01

    Full Text Available Taking into consideration the importance and role of children in modern society, as well as their position, this article has as its focus juveniles in criminal procedure. The existence of a separate juvenile justice system independent of the criminal law applicable to the adult offenders and general criminal procedure, as well as the periodic changes of the dominant approach in theory and practice reflects the ascendancy of different theoretical perspectives in the juvenile justice. In this paper, the authors scrutinize the models of responding to juvenile crime - justice and welfare model - as two models of the greatest importance in the present reaction of the society to the crimes conducted by the youngest delinquents at the beginning of the new century and millennium. Furthermore, the paper deals with a matter of international legal standards which, to a large extent, give shape to the legal framework for juvenile offenders and provide their rights and position in the criminal procedure. The authors refer to the internationally accepted documents on several levels. From the (almost universally accepted multilateral conventions on human rights, through the field of recommendations, rules and guidelines which are obeyed and enforced in practice of the juvenile justice although they are of non-binding nature, via the regional European legislative to the national provisions in a particular number of countries. On all the levels mentioned above the rights of the juveniles are regulated having in mind their possible role in the criminal procedure as a perpetrator of a criminal act, as a victim or as a witness. This paper also analyzes the criminal procedure with respect to juvenile perpetrators of the criminal acts in the Republic of Serbia and compliance of the provisions currently in vigor with the international legal standards contained in the international conventions and other internationally accepted and recognized instruments.

  6. Numerical Analysis of Asymptotic Stability of Equilibrium Points

    Directory of Open Access Journals (Sweden)

    A. A. Vorkel

    2017-01-01

    Full Text Available The aim of this study is to numerically analyze an asymptotic stability of the equilibrium points of autonomous systems of ordinary differential equations on the basis of the asymptotic stability criterion given in the article and the functional localization method of invariant compact sets. The article formulates the necessary and sufficient conditions for an asymptotic stability in terms of invariant compact sets and positively invariant sets and describes a functional localization method. Presents appropriate localization theorems for invariant compact sets of dynamical systems.To investigate the asymptotic stability is proposed an algorithm for a numerical iteration procedure to construct the localizing bounds for invariant compact sets contained in a given initial set. Application of the asymptotic stability criterion is based on the results of this procedure. The author of the article verifies the conditions of the appropriate theorem and confirms the use of this criterion.The examples of two- and three-dimensional systems of differential equations demonstrate a principle of the iteration procedure. The article also gives an example of the system with a limit cycle and it shows that the developed numerical algorithm and the functional localization method of invariant compact sets can be used to analyze stability of the limit cycles.Thanks to the method described in the article, when analyzing an asymptotic stability of equilibrium points, finding a Lyapunov function and calculating eigenvalues of a matrix of linear approximation are non-essential. Thus, it is possible to avoid labour-intensive work with complex analytical structures.The numerical iteration procedure can be used in systems of different dimensions and makes the presented algorithm of asymptotic stability analysis universal.

  7. Building a rapid response team.

    Science.gov (United States)

    Halvorsen, Lisa; Garolis, Salomeja; Wallace-Scroggs, Allyson; Stenstrom, Judy; Maunder, Richard

    2007-01-01

    The use of rapid response teams is a relatively new approach for decreasing or eliminating codes in acute care hospitals. Based on the principles of a code team for cardiac and/or respiratory arrest in non-critical care units, the rapid response teams have specially trained nursing, respiratory, and medical personnel to respond to calls from general care units to assess and manage decompensating or rapidly changing patients before their conditions escalate to a full code situation. This article describes the processes used to develop a rapid response team, clinical indicators for triggering a rapid response team call, topics addressed in an educational program for the rapid response team members, and methods for evaluating effectiveness of the rapid response team.

  8. Numeric tools for tachogram analyse

    Directory of Open Access Journals (Sweden)

    Artur RYGUŁA

    2007-01-01

    Full Text Available Paper describes numeric application supporting driving analysis process on attitude of tachogram data. Actual accessible units recording road and speed in function of the time were used. Also potential optimisation areas of driving were shown. Additionally in the paper are presented road safety level in Poland in the context of dangerous driver’s behaviour.

  9. Numerical Modeling of Advanced materials

    NARCIS (Netherlands)

    Meinders, Vincent T.; Perdahcioglu, Emin Semih; van Riel, M.; Wisselink, H.H.

    2008-01-01

    The finite element (FE) method is widely used to numerically simulate forming processes. The accuracy of an FE analysis strongly depends on the extent to which a material model can represent the real material behavior. The use of new materials requires complex material models which are able to

  10. A universal, rapid, and inexpensive method for genomic DNA ...

    Indian Academy of Sciences (India)

    MOHAMMED BAQUR SAHIB A. AL-SHUHAIB

    Abstract. There is no 'one' procedure for extracting DNA from the whole blood of both mammals and birds, since each species has a unique property that require different methods to release its own DNA. Therefore, to obtain genomic DNA, a universal, rapid, and noncostly method was developed. A very simple biological ...

  11. A field technique for rapid lithological discrimination and ore mineral ...

    Indian Academy of Sciences (India)

    This work illustrates the efficiency of field spectroscopy for rapid identification of minerals in ore body, alteration zone and host rocks. The adopted procedure involves collection of field spectra, their pro- cessing for noise, spectral matching and spectral un-mixing with selected library end-members. Average weighted ...

  12. A field technique for rapid lithological discrimination and ore mineral ...

    Indian Academy of Sciences (India)

    This work illustrates the efficiency of field spectroscopy for rapid identification of minerals in ore body, alteration zone and host rocks. The adopted procedure involves collection of field spectra, their processing for noise, spectral matching and spectral un-mixing with selected library end-members. Average weighted spectral ...

  13. A novel approach for rapid micropropagation of maspine pineapple ...

    African Journals Online (AJOL)

    A novel approach for rapid micropropagation of maspine pineapple ( Ananas comosus L.) shoots using liquid shake culture system. ... Large quantities of plant materials are needed to fulfill the market demand which could not be obtained from the conventional breeding method. Hence, in vitro procedure was developed as ...

  14. Diagnosing herpesvirus infections by real time amplification and rapid culture.

    NARCIS (Netherlands)

    J. Guldemeester; A.D.M.E. Osterhaus (Albert); H.G.M. Niesters (Bert); G.J.J. van Doornum (Gerard)

    2003-01-01

    textabstractProcedures using real-time technique were developed to demonstrate the presence of herpes simplex virus type 1 (HSV-1) and HSV-2, varicella zoster virus (VZV), and cytomegalovirus (CMV) in miscellaneous clinical specimens. The assays were compared to rapid culture using centrifugation

  15. A universal, rapid, and inexpensive method for genomic DNA ...

    Indian Academy of Sciences (India)

    ... of both mammals and birds, since each species has a unique property that require different methods to release its own DNA. Therefore, to obtain genomic DNA, a universal, rapid, and noncostly method was developed. A very simple biological basis is followed in this procedure, in which, when the bloodis placed in water, ...

  16. Problems of rapid growth.

    Science.gov (United States)

    Kim, T D

    1980-01-01

    South Korea's export-oriented development strategy has achieved a remarkable growth record, but it has also brought 2 different problems: 1) since the country's exports accounted for about 1% of total world export volume, the 1st world has become fearful about Korea's aggressive export drive; and 2) the fact that exports account for over 30% of its total gross national product (GNP) exposes the vulnerability of South Korea's economy itself. South Korea continues to be a poor nation, although it is rated as 1 of the most rapidly growing middle income economies. A World Bank 1978 report shows Korea to be 28th of 58 middle income countries in terms of per capita GNP in 1976. Of 11 newly industrializing countries (NIC), 5 in the European continent are more advanced than the others. A recent emphasis on the basic human needs approach has tended to downgrade the concept of GNP. Korea has only an abundant labor force and is without any natural resources. Consequently, Korea utilized an export-oriented development strategy. Oil requirements are met with imports, and almost all raw materials to be processed into exportable products must be imported. To pay import bills Korea must export and earn foreign exchange. It must be emphasized that foreign trade must always be 2-way traffic. In order to export more to middle income countries like Korea, the countries of the 1st world need to ease their protectionist measures against imports from developing countries.

  17. Rapid Polymer Sequencer

    Science.gov (United States)

    Stolc, Viktor (Inventor); Brock, Matthew W (Inventor)

    2013-01-01

    Method and system for rapid and accurate determination of each of a sequence of unknown polymer components, such as nucleic acid components. A self-assembling monolayer of a selected substance is optionally provided on an interior surface of a pipette tip, and the interior surface is immersed in a selected liquid. A selected electrical field is impressed in a longitudinal direction, or in a transverse direction, in the tip region, a polymer sequence is passed through the tip region, and a change in an electrical current signal is measured as each polymer component passes through the tip region. Each of the measured changes in electrical current signals is compared with a database of reference electrical change signals, with each reference signal corresponding to an identified polymer component, to identify the unknown polymer component with a reference polymer component. The nanopore preferably has a pore inner diameter of no more than about 40 nm and is prepared by heating and pulling a very small section of a glass tubing.

  18. Rapidly rotating red giants

    Science.gov (United States)

    Gehan, Charlotte; Mosser, Benoît; Michel, Eric

    2017-10-01

    Stellar oscillations give seismic information on the internal properties of stars. Red giants are targets of interest since they present mixed modes, wich behave as pressure modes in the convective envelope and as gravity modes in the radiative core. Mixed modes thus directly probe red giant cores, and allow in particular the study of their mean core rotation. The high-quality data obtained by CoRoT and Kepler satellites represent an unprecedented perspective to obtain thousands of measurements of red giant core rotation, in order to improve our understanding of stellar physics in deep stellar interiors. We developed an automated method to obtain such core rotation measurements and validated it for stars on the red giant branch. In this work, we particularly focus on the specific application of this method to red giants having a rapid core rotation. They show complex spectra where it is tricky to disentangle rotational splittings from mixed-mode period spacings. We demonstrate that the method based on the identification of mode crossings is precise and efficient. The determination of the mean core rotation directly derives from the precise measurement of the asymptotic period spacing ΔΠ1 and of the frequency at which the crossing of the rotational components is observed.

  19. Numerical and experimental investigation of nonswirling and swirling confined jets

    Science.gov (United States)

    Brondum, D. C.; Bennett, J. C.; Weinberg, B. C.; Mcdonald, H.

    1986-01-01

    An investigation of the influence of large scale structures on the flow development for coaxial jets with sudden expansion (with and without swirl) is presented. Both an experimental study and numerical predictions were performed for a configuration corresponding to that considered by Johnson and Bennett and Roback and Johnson. The effects of large scale structures on the swirling and nonswirling flows are documented, in particular their influence on turbulence modeling and the numerical simulation. The ensemble-averaged, time-dependent Navier-Stokes equations are solved by an LBI procedure to predict the turbulent flow field. Effects of artificial dissipation and placement of the upstream boundary in the numerical computation are also discussed.

  20. Framatome-ANP experience in numerical simulation of welding

    Energy Technology Data Exchange (ETDEWEB)

    Gilles, P. [FRAMATOME ANP SAS, NFPM, 92 - Paris-La-Defence (France); Pont, D. [FRAMATOME ANP SAS, NFVED, 69 - Lyon (France); Keim, E. [Framatome ANP GmbH -NGTM, Erlangen (Germany); Devaux, J. [ESI France, 69 - Lyon (France)

    2004-07-01

    For nuclear reactor manufacturers, ensuring a high quality of welded joints is one of the basic design rules. Qualification of welders, specific procedures, stress relief heat treatments serve efficiently this goal. Numerical simulation of welding adds the capability of assessing residual stresses, distortions, and in a near future quality of welds. Since almost 25 years, Framatome-ANP has been working on numerical simulation of welding to improve predictions and efficiency of computational tools, namely using the worldwide known SYSWELD. The largest part of Framatome-ANP experience in this field relies in the numerous studies performed by German and French teams on industrial components. This paper tries to account for all these efforts, following a presentation oriented on types of problem. (authors)

  1. Mathematical properties of numerical inversion for jet calibrations

    Energy Technology Data Exchange (ETDEWEB)

    Cukierman, Aviv [Physics Department, Stanford University, Stanford, CA 94305 (United States); SLAC National Accelerator Laboratory, Stanford University, Menlo Park, CA 94025 (United States); Nachman, Benjamin, E-mail: bnachman@cern.ch [Physics Department, Stanford University, Stanford, CA 94305 (United States); SLAC National Accelerator Laboratory, Stanford University, Menlo Park, CA 94025 (United States); Physics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94704 (United States)

    2017-06-21

    Numerical inversion is a general detector calibration technique that is independent of the underlying spectrum. This procedure is formalized and important statistical properties are presented, using high energy jets at the Large Hadron Collider as an example setting. In particular, numerical inversion is inherently biased and common approximations to the calibrated jet energy tend to over-estimate the resolution. Analytic approximations to the closure and calibrated resolutions are demonstrated to effectively predict the full forms under realistic conditions. Finally, extensions of numerical inversion are presented which can reduce the inherent biases. These methods will be increasingly important to consider with degraded resolution at low jet energies due to a much higher instantaneous luminosity in the near future.

  2. An Explicit Numerical Method for the Fractional Cable Equation

    Directory of Open Access Journals (Sweden)

    J. Quintana-Murillo

    2011-01-01

    Full Text Available An explicit numerical method to solve a fractional cable equation which involves two temporal Riemann-Liouville derivatives is studied. The numerical difference scheme is obtained by approximating the first-order derivative by a forward difference formula, the Riemann-Liouville derivatives by the Grünwald-Letnikov formula, and the spatial derivative by a three-point centered formula. The accuracy, stability, and convergence of the method are considered. The stability analysis is carried out by means of a kind of von Neumann method adapted to fractional equations. The convergence analysis is accomplished with a similar procedure. The von-Neumann stability analysis predicted very accurately the conditions under which the present explicit method is stable. This was thoroughly checked by means of extensive numerical integrations.

  3. Mathematical properties of numerical inversion for jet calibrations

    Science.gov (United States)

    Cukierman, Aviv; Nachman, Benjamin

    2017-06-01

    Numerical inversion is a general detector calibration technique that is independent of the underlying spectrum. This procedure is formalized and important statistical properties are presented, using high energy jets at the Large Hadron Collider as an example setting. In particular, numerical inversion is inherently biased and common approximations to the calibrated jet energy tend to over-estimate the resolution. Analytic approximations to the closure and calibrated resolutions are demonstrated to effectively predict the full forms under realistic conditions. Finally, extensions of numerical inversion are presented which can reduce the inherent biases. These methods will be increasingly important to consider with degraded resolution at low jet energies due to a much higher instantaneous luminosity in the near future.

  4. Droplet centrifugation, droplet DNA extraction, and rapid droplet thermocycling for simpler and faster PCR assay using wire-guided manipulations

    Directory of Open Access Journals (Sweden)

    You David J

    2012-09-01

    Full Text Available Abstract A computer numerical control (CNC apparatus was used to perform droplet centrifugation, droplet DNA extraction, and rapid droplet thermocycling on a single superhydrophobic surface and a multi-chambered PCB heater. Droplets were manipulated using “wire-guided” method (a pipette tip was used in this study. This methodology can be easily adapted to existing commercial robotic pipetting system, while demonstrated added capabilities such as vibrational mixing, high-speed centrifuging of droplets, simple DNA extraction utilizing the hydrophobicity difference between the tip and the superhydrophobic surface, and rapid thermocycling with a moving droplet, all with wire-guided droplet manipulations on a superhydrophobic surface and a multi-chambered PCB heater (i.e., not on a 96-well plate. Serial dilutions were demonstrated for diluting sample matrix. Centrifuging was demonstrated by rotating a 10 μL droplet at 2300 round per minute, concentrating E. coli by more than 3-fold within 3 min. DNA extraction was demonstrated from E. coli sample utilizing the disposable pipette tip to cleverly attract the extracted DNA from the droplet residing on a superhydrophobic surface, which took less than 10 min. Following extraction, the 1500 bp sequence of Peptidase D from E. coli was amplified using rapid droplet thermocycling, which took 10 min for 30 cycles. The total assay time was 23 min, including droplet centrifugation, droplet DNA extraction and rapid droplet thermocycling. Evaporation from of 10 μL droplets was not significant during these procedures, since the longest time exposure to air and the vibrations was less than 5 min (during DNA extraction. The results of these sequentially executed processes were analyzed using gel electrophoresis. Thus, this work demonstrates the adaptability of the system to replace many common laboratory tasks on a single platform (through re-programmability, in rapid succession (using droplets

  5. Inter-specific differences in numerical abilities among teleost fish

    Directory of Open Access Journals (Sweden)

    Christian eAgrillo

    2012-11-01

    Full Text Available Adults, infants and non-human primates are thought to possess similar non-verbal numerical systems, but there is considerable debate regarding whether all vertebrates share the same numerical abilities. Despite an abundance of studies, cross-species comparison remains difficult because the methodology employed and the context of species examination vary considerably across studies. To fill this gap, we used the same procedure, stimuli and numerical contrasts to compare quantity abilities of five teleost fish: redtail splitfin, guppies, zebrafish, Siamese fighting fish, and angelfish. Subjects were trained to discriminate between two sets of geometrical figures using a food reward. Fish initially were trained on an easy numerical ratio (5 vs. 10 and 6 vs. 12. Once they reached the learning criterion, they were subjected to non-reinforced probe trials in which the set size was constant but numerical ratios varied (8 vs. 12 and 9 vs. 12. They also were subjected to probe trials in which the ratio was constant, but the total set size was increased (25 vs. 50 or decreased (2 vs. 4. Overall, fish generalized to numerosities with a 0.67 ratio, but failed with a 0.75 ratio; they generalized to a smaller set size, but not to a larger one. Only minor differences were observed among the five species. However, in one species, zebrafish, the proportion of individuals reaching the learning criterion was much smaller than in the others. In a control experiment, zebrafish showed a similar lower performance in shape discrimination, suggesting that the observed difference resulted from the zebrafish’s difficulty in learning this procedure rather than from a cross-species variation in the numerical domain.

  6. Rapid mixing kinetic techniques.

    Science.gov (United States)

    Martin, Stephen R; Schilstra, Maria J

    2013-01-01

    Almost all of the elementary steps in a biochemical reaction scheme are either unimolecular or bimolecular processes that frequently occur on sub-second, often sub-millisecond, time scales. The traditional approach in kinetic studies is to mix two or more reagents and monitor the changes in concentrations with time. Conventional spectrophotometers cannot generally be used to study reactions that are complete within less than about 20 s, as it takes that amount of time to manually mix the reagents and activate the instrument. Rapid mixing techniques, which generally achieve mixing in less than 2 ms, overcome this limitation. This chapter is concerned with the use of these techniques in the study of reactions which reach equilibrium; the application of these methods to the study of enzyme kinetics is described in several excellent texts (Cornish-Bowden, Fundamentals of enzyme kinetics. Portland Press, 1995; Gutfreund, Kinetics for the life sciences. Receptors, transmitters and catalysis. Cambridge University Press, 1995).There are various ways to monitor changes in concentration of reactants, intermediates and products after mixing, but the most common way is to use changes in optical signals (absorbance or fluorescence) which often accompany reactions. Although absorbance can sometimes be used, fluorescence is often preferred because of its greater sensitivity, particularly in monitoring conformational changes. Such methods are continuous with good time resolution but they seldom permit the direct determination of the concentrations of individual species. Alternatively, samples may be taken from the reaction volume, mixed with a chemical quenching agent to stop the reaction, and their contents assessed by techniques such as HPLC. These methods can directly determine the concentrations of different species, but are discontinuous and have a limited time resolution.

  7. RNAV STAR Procedural Adherence

    Science.gov (United States)

    Stewart, Michael J.; Matthews, Bryan L.

    2017-01-01

    In this exploratory archival study we mined the performance of 24 major US airports area navigation standard terminal arrival routes (RNAV STARs) over the preceding three years. Overlaying radar track data on top of RNAV STAR routes provided a comparison between aircraft flight paths and the waypoint positions and altitude restrictions. NASA Ames Supercomputing resources were utilized to perform the data mining and processing. We investigated STARs by lateral transition path (full-lateral), vertical restrictions (full-lateral/full-vertical), and skipped waypoints (skips). In addition, we graphed altitudes and their frequencies of occurrence for altitude restrictions. Full-lateral compliance was generally greater than Full-lateral/full-vertical, but the delta between the rates was not always consistent. Full-lateral/full-vertical usage medians of the 2016 procedures ranged from 0 in KDEN (Denver) to 21 in KMEM (Memphis). Waypoint skips ranged from 0 to nearly 100 for specific waypoints. Altitudes restrictions were sometimes missed by systemic amounts in 1000 ft. increments from the restriction, creating multi-modal distributions. Other times, altitude misses looked to be more normally distributed around the restriction. This work is a preliminary investigation into the objective performance of instrument procedures and provides a framework to track how procedural concepts and design intervention function. In addition, this tool may aid in providing acceptability metrics as well as risk assessment information.

  8. Solid modeling and applications rapid prototyping, CAD and CAE theory

    CERN Document Server

    Um, Dugan

    2016-01-01

    The lessons in this fundamental text equip students with the theory of Computer Assisted Design (CAD), Computer Assisted Engineering (CAE), the essentials of Rapid Prototyping, as well as practical skills needed to apply this understanding in real world design and manufacturing settings. The book includes three main areas: CAD, CAE, and Rapid Prototyping, each enriched with numerous examples and exercises. In the CAD section, Professor Um outlines the basic concept of geometric modeling, Hermite and Bezier Spline curves theory, and 3-dimensional surface theories as well as rendering theory. The CAE section explores mesh generation theory, matrix notion for FEM, the stiffness method, and truss Equations. And in Rapid Prototyping, the author illustrates stereo lithographic theory and introduces popular modern RP technologies. Solid Modeling and Applications: Rapid Prototyping, CAD and CAE Theory is ideal for university students in various engineering disciplines as well as design engineers involved in product...

  9. Numerical methods for metamaterial design

    CERN Document Server

    2013-01-01

    This book describes a relatively new approach for the design of electromagnetic metamaterials.  Numerical optimization routines are combined with electromagnetic simulations to tailor the broadband optical properties of a metamaterial to have predetermined responses at predetermined wavelengths. After a review of both the major efforts within the field of metamaterials and the field of mathematical optimization, chapters covering both gradient-based and derivative-free design methods are considered.  Selected topics including surrogate-base optimization, adaptive mesh search, and genetic algorithms are shown to be effective, gradient-free optimization strategies.  Additionally, new techniques for representing dielectric distributions in two dimensions, including level sets, are demonstrated as effective methods for gradient-based optimization.  Each chapter begins with a rigorous review of the optimization strategy used, and is followed by numerous examples that combine the strategy with either electromag...

  10. Numerical and Evolutionary Optimization Workshop

    CERN Document Server

    Trujillo, Leonardo; Legrand, Pierrick; Maldonado, Yazmin

    2017-01-01

    This volume comprises a selection of works presented at the Numerical and Evolutionary Optimization (NEO) workshop held in September 2015 in Tijuana, Mexico. The development of powerful search and optimization techniques is of great importance in today’s world that requires researchers and practitioners to tackle a growing number of challenging real-world problems. In particular, there are two well-established and widely known fields that are commonly applied in this area: (i) traditional numerical optimization techniques and (ii) comparatively recent bio-inspired heuristics. Both paradigms have their unique strengths and weaknesses, allowing them to solve some challenging problems while still failing in others. The goal of the NEO workshop series is to bring together people from these and related fields to discuss, compare and merge their complimentary perspectives in order to develop fast and reliable hybrid methods that maximize the strengths and minimize the weaknesses of the underlying paradigms. Throu...

  11. Simulation of Numerical Distance Relays

    OpenAIRE

    Sherwali, Hamid; Abdlrahem, Abdlmnam

    2010-01-01

    As modern numerical relays are widely employed in protection systems nowadays and modeling of these types of relays is important to adjust and settle protection equipment in electrical facilities and to train protection personnel, the simulation of distance relays using MATLAB offers a good opportunity to perform these activities efficiently and with minimum cost. Another advantages is that, as MATLAB is a powerful tool rich with component models, any shape of relay characteristic (Impedance,...

  12. Cuba: Multidimensional numerical integration library

    Science.gov (United States)

    Hahn, Thomas

    2016-08-01

    The Cuba library offers four independent routines for multidimensional numerical integration: Vegas, Suave, Divonne, and Cuhre. The four algorithms work by very different methods, and can integrate vector integrands and have very similar Fortran, C/C++, and Mathematica interfaces. Their invocation is very similar, making it easy to cross-check by substituting one method by another. For further safeguarding, the output is supplemented by a chi-square probability which quantifies the reliability of the error estimate.

  13. Metaprogramming Applied to Numerical Problems

    Science.gov (United States)

    Mulansky, Mario; Ahnert, Karsten

    2011-09-01

    From the discovery that the template system of C++ forms a Turing complete language in 1994, a programming technique called Template Metaprogramming has emerged that allows for the creation of faster, more generic and better code. Here, we apply Template Metaprogramming to implement a generic Runge-Kutta scheme that can be used to numerically solve ordinary differential equations. We show that using Template Metaprogramming results in a significantly improved performance compared to a classical implementation.

  14. Numerical and symbolic scientific computing

    CERN Document Server

    Langer, Ulrich

    2011-01-01

    The book presents the state of the art and results and also includes articles pointing to future developments. Most of the articles center around the theme of linear partial differential equations. Major aspects are fast solvers in elastoplasticity, symbolic analysis for boundary problems, symbolic treatment of operators, computer algebra, and finite element methods, a symbolic approach to finite difference schemes, cylindrical algebraic decomposition and local Fourier analysis, and white noise analysis for stochastic partial differential equations. Further numerical-symbolic topics range from

  15. Numerical Optimization Using Desktop Computers

    Science.gov (United States)

    1980-09-11

    comute progeams w.ee Edevelpe in advnce BASICto perform numerical optimization of a user supplied design problem on the Hewlett Packard 9845A desktop...a particular design problem. The general optimization problem may thus be stated mathematically as: Find the set of design variables Xi where i =1,2...OPCON and DESOP, provide the capability for finding the optimum design of a system mathematically modeled using multiple variables, on the Hewlett

  16. Numerical precision and data structures

    Science.gov (United States)

    Schenk, W.

    1978-01-01

    Technical proposals and recommendations for revising FORTRAN were studied and categorized. In the area of numerical precision, the proposals basically agree on a set of necessary parameters, although a wide range of nomenclature and specific function names are used. Environmental parameters identified include the following: (1) base of floating point representation, (2) largest positive real number, exponent and integer, (3) largest negative real number, exponent and integer, (4) number of significant digits, and (5) exponent bias.

  17. Brake squeal: Linear and nonlinear numerical approaches

    Science.gov (United States)

    Massi, Francesco; Baillet, Laurent; Giannini, Oliviero; Sestieri, Aldo

    2007-08-01

    "Brake squeal" groups a large set of high-frequency sound emissions from brake systems. They are generated during the braking phase and are characterized by a harmonic spectrum. The onset of squeal is due to an unstable behaviour occurring in linear conditions during the braking phase, and a general approach used by several authors to determine the system instabilities is the complex eigenvalues analysis. When the brake begins to squeal, the response of the system reaches a new limit cycle where the linear models cannot be used anymore. This paper presents the integration of two different numerical procedures to identify the mechanism bringing to squeal instability and to analyse its dynamics. The first approach is a finite element modal analysis of the brake system and is used to identify its eigenvalues and to relate them to the squeal occurrence. The second one is a specific finite element programme, Plast3, appropriate for nonlinear dynamic analyses in the time domain and is particularly addressed to study contact problems with friction between deformable bodies. This programme computes the contact stresses and permits to determine the dynamics of the system along the contact surface, both in the linear and nonlinear fields. The two models are compared and the onset of squeal is predicted both in the frequency domain by the linear model and in the time domain by the nonlinear one. The instability predictions, obtained by the two models, are discussed. To simplify the dynamics of its components, the study is carried out on a simple model, made of a disc, a small friction pad and a beam supporting the pad. The geometry of the model is related to an experimental set-up used to validate the models and to compare the numerical results with the experiments.

  18. Numerical ability predicts mortgage default.

    Science.gov (United States)

    Gerardi, Kristopher; Goette, Lorenz; Meier, Stephan

    2013-07-09

    Unprecedented levels of US subprime mortgage defaults precipitated a severe global financial crisis in late 2008, plunging much of the industrialized world into a deep recession. However, the fundamental reasons for why US mortgages defaulted at such spectacular rates remain largely unknown. This paper presents empirical evidence showing that the ability to perform basic mathematical calculations is negatively associated with the propensity to default on one's mortgage. We measure several aspects of financial literacy and cognitive ability in a survey of subprime mortgage borrowers who took out loans in 2006 and 2007, and match them to objective, detailed administrative data on mortgage characteristics and payment histories. The relationship between numerical ability and mortgage default is robust to controlling for a broad set of sociodemographic variables, and is not driven by other aspects of cognitive ability. We find no support for the hypothesis that numerical ability impacts mortgage outcomes through the choice of the mortgage contract. Rather, our results suggest that individuals with limited numerical ability default on their mortgage due to behavior unrelated to the initial choice of their mortgage.

  19. Sepsis and multiorgan failure following TVT procedure.

    Science.gov (United States)

    Stec, Piotr; Connell, Rowan

    2014-04-01

    Tension-free vaginal tape (TVT), is a commonly performed, low risk procedure for treatment of stress urinary incontinence (SUI). Severe complications are rare, but can be potentially life threatening. We present a case of 66 year old patient who sustained bladder perforation at the time of TVT procedure and subsequently developed sepsis rapidly leading to multi-organ failure and triggering sequence of serious complications. During her inpatient stay she required ITU admission, emergency laparotomy, TVT mesh removal, bowel resection due to ischemic colitis and anticoagulation for pulmonary embolism. Despite of clinical picture of sepsis her microbiology tests were almost consistently negative. This case emphasise importance of awareness and quick recognition of TVT related complications. Patient ultimately survived and recovered thanks to timely and coordinated management by the multidisciplinary team of doctors.

  20. A Perceptual-Like Population-Coding Mechanism of Approximate Numerical Averaging.

    Science.gov (United States)

    Brezis, Noam; Bronfman, Zohar Z; Usher, Marius

    2018-02-01

    Humans possess a remarkable ability to rapidly form coarse estimations of numerical averages. This ability is important for making decisions that are based on streams of numerical or value-based information, as well as for preference formation. Nonetheless, the mechanism underlying rapid approximate numerical averaging remains unknown, and several competing mechanism may account for it. Here, we tested the hypothesis that approximate numerical averaging relies on perceptual-like processes, instantiated by population coding. Participants were presented with rapid sequences of numerical values (four items per second) and were asked to convey the sequence average. We manipulated the sequences' length, variance, and mean magnitude and found that similar to perceptual averaging, the precision of the estimations improves with the length and deteriorates with (higher) variance or (higher) magnitude. To account for the results, we developed a biologically plausible population-coding model and showed that it is mathematically equivalent to a population vector. Using both quantitative and qualitative model comparison methods, we compared the population-coding model to several competing models, such as a step-by-step running average (based on leaky integration) and a midrange model. We found that the data support the population-coding model. We conclude that humans' ability to rapidly form estimations of numerical averages has many properties of the perceptual (intuitive) system rather than the arithmetic, linguistic-based (analytic) system and that population coding is likely to be its underlying mechanism.

  1. Rapid Active Sampling Package

    Science.gov (United States)

    Peters, Gregory

    2010-01-01

    A field-deployable, battery-powered Rapid Active Sampling Package (RASP), originally designed for sampling strong materials during lunar and planetary missions, shows strong utility for terrestrial geological use. The technology is proving to be simple and effective for sampling and processing materials of strength. Although this originally was intended for planetary and lunar applications, the RASP is very useful as a powered hand tool for geologists and the mining industry to quickly sample and process rocks in the field on Earth. The RASP allows geologists to surgically acquire samples of rock for later laboratory analysis. This tool, roughly the size of a wrench, allows the user to cut away swaths of weathering rinds, revealing pristine rock surfaces for observation and subsequent sampling with the same tool. RASPing deeper (.3.5 cm) exposes single rock strata in-situ. Where a geologist fs hammer can only expose unweathered layers of rock, the RASP can do the same, and then has the added ability to capture and process samples into powder with particle sizes less than 150 microns, making it easier for XRD/XRF (x-ray diffraction/x-ray fluorescence). The tool uses a rotating rasp bit (or two counter-rotating bits) that resides inside or above the catch container. The container has an open slot to allow the bit to extend outside the container and to allow cuttings to enter and be caught. When the slot and rasp bit are in contact with a substrate, the bit is plunged into it in a matter of seconds to reach pristine rock. A user in the field may sample a rock multiple times at multiple depths in minutes, instead of having to cut out huge, heavy rock samples for transport back to a lab for analysis. Because of the speed and accuracy of the RASP, hundreds of samples can be taken in one day. RASP-acquired samples are small and easily carried. A user can characterize more area in less time than by using conventional methods. The field-deployable RASP used a Ni

  2. Quantifying uncertainty in the phylogenetics of Australian numeral systems.

    Science.gov (United States)

    Zhou, Kevin; Bowern, Claire

    2015-09-22

    Researchers have long been interested in the evolution of culture and the ways in which change in cultural systems can be reconstructed and tracked. Within the realm of language, these questions are increasingly investigated with Bayesian phylogenetic methods. However, such work in cultural phylogenetics could be improved by more explicit quantification of reconstruction and transition probabilities. We apply such methods to numerals in the languages of Australia. As a large phylogeny with almost universal 'low-limit' systems, Australian languages are ideal for investigating numeral change over time. We reconstruct the most likely extent of the system at the root and use that information to explore the ways numerals evolve. We show that these systems do not increment serially, but most commonly vary their upper limits between 3 and 5. While there is evidence for rapid system elaboration beyond the lower limits, languages lose numerals as well as gain them. We investigate the ways larger numerals build on smaller bases, and show that there is a general tendency to both gain and replace 4 by combining 2 + 2 (rather than inventing a new unanalysable word 'four'). We develop a series of methods for quantifying and visualizing the results. © 2015 The Author(s).

  3. Rapid Robot Design Validation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Energid Technologies will create a comprehensive software infrastructure for rapid validation of robotic designs. The software will support push-button validation...

  4. Rapid Robot Design Validation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Energid Technologies will create a comprehensive software infrastructure for rapid validation of robot designs. The software will support push-button validation...

  5. Rapid detection of fungal alpha-amylase in the work environment with a lateral flow immunoassay

    NARCIS (Netherlands)

    Bogdanovic, J.; Koets, M.; Sander, I.; Wouters, I.; Meijster, T.; Heederik, D.J.J.; Amerongen, van A.; Doekes, G.

    2006-01-01

    Background Occupational allergen exposure assessment usually requires airborne dust sampling at the worksite followed by dust extraction and enzyme immunoassay (EIA) analysis at the laboratory. Use of semiquantitative lateral flow immunoassays (LFIAs) may allow a more rapid detection procedure with

  6. Using a Microscale Approach to Rapidly Separate and Characterize Three Photosynthetic Pigment Species from Fern

    Science.gov (United States)

    Ayudhya, Theppawut Israsena Na; Posey, Frederick T.; Tyus, Jessica C.; Dingra, Nin N.

    2015-01-01

    A rapid separation of three photosynthetic pigments (chlorophyll "a" and "b" and xanthophyll) from fern ("Polystichum acrostichoides") is described using microscale solvent extraction and traditional thin layer chromatography that minimizes use of harmful chemicals and lengthy procedures. The experiment introduces…

  7. The numerical evaluation of the minimal outlet area of the safety valve in the pipelines of cryogenic installations

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    The flow of cold helium in pipes is a fundamental issue of any cryogenic installation. Pipelines for helium transportation can reach lengths of hundreds of meters. The proper selection of size for individual pipelines and safety valves is a crucial part in the consideration of costs for the entire installation and its safe operation. The size of the safety valve must be properly designed in order to avoid a dangerous pressure buildup during normal operation, as well as in the case of emergency. The most commonly occurring dangerous situation is an undesired heat flux in the helium as a result of a broken insulation. In this case, the heat flux can be very intense and the buildup of the pressure in the pipe can be very rapid. In the present work, numerical calculations were used to evaluate the buildup of pressure and temperature in the pipe, in the case of a sudden and intense heat flux. The main goal of the applied numerical procedure was to evaluate the proper sizes of the safety valves in order to avoid a...

  8. Multiple-source multiple-harmonic active vibration control of variable section cylindrical structures: A numerical study

    Science.gov (United States)

    Liu, Jinxin; Chen, Xuefeng; Gao, Jiawei; Zhang, Xingwu

    2016-12-01

    Air vehicles, space vehicles and underwater vehicles, the cabins of which can be viewed as variable section cylindrical structures, have multiple rotational vibration sources (e.g., engines, propellers, compressors and motors), making the spectrum of noise multiple-harmonic. The suppression of such noise has been a focus of interests in the field of active vibration control (AVC). In this paper, a multiple-source multiple-harmonic (MSMH) active vibration suppression algorithm with feed-forward structure is proposed based on reference amplitude rectification and conjugate gradient method (CGM). An AVC simulation scheme called finite element model in-loop simulation (FEMILS) is also proposed for rapid algorithm verification. Numerical studies of AVC are conducted on a variable section cylindrical structure based on the proposed MSMH algorithm and FEMILS scheme. It can be seen from the numerical studies that: (1) the proposed MSMH algorithm can individually suppress each component of the multiple-harmonic noise with an unified and improved convergence rate; (2) the FEMILS scheme is convenient and straightforward for multiple-source simulations with an acceptable loop time. Moreover, the simulations have similar procedure to real-life control and can be easily extended to physical model platform.

  9. Algorithm Development and Application of High Order Numerical Methods for Shocked and Rapid Changing Solutions

    Science.gov (United States)

    2007-12-06

    high order well-balanced schemes to a class of hyperbolic systems with source terms, Boletin de la Sociedad Espanola de Matematica Aplicada, v34 (2006...schemes to a class of hyperbolic systems with source terms, Boletin de la Sociedad Espanola de Matematica Aplicada, v34 (2006), pp.69-80. 39. Y. Xu and C.-W

  10. How to Rapidly Construct a Spatial-Numerical Representation in Preliterate Children (At Least Temporarily)

    Science.gov (United States)

    Patro, Katarzyna; Fischer, Ursula; Nuerk, Hans-Christoph; Cress, Ulrike

    2016-01-01

    Spatial processing of numbers has emerged as one of the basic properties of humans' mathematical thinking. However, how and when number-space relations develop is a highly contested issue. One dominant view has been that a link between numbers and left/right spatial directions is constructed based on directional experience associated with reading…

  11. Mixed-reality simulation for neurosurgical procedures.

    Science.gov (United States)

    Bova, Frank J; Rajon, Didier A; Friedman, William A; Murad, Gregory J; Hoh, Daniel J; Jacob, R Patrick; Lampotang, Samsun; Lizdas, David E; Lombard, Gwen; Lister, J Richard

    2013-10-01

    Surgical education is moving rapidly to the use of simulation for technical training of residents and maintenance or upgrading of surgical skills in clinical practice. To optimize the learning exercise, it is essential that both visual and haptic cues are presented to best present a real-world experience. Many systems attempt to achieve this goal through a total virtual interface. To demonstrate that the most critical aspect in optimizing a simulation experience is to provide the visual and haptic cues, allowing the training to fully mimic the real-world environment. Our approach has been to create a mixed-reality system consisting of a physical and a virtual component. A physical model of the head or spine is created with a 3-dimensional printer using deidentified patient data. The model is linked to a virtual radiographic system or an image guidance platform. A variety of surgical challenges can be presented in which the trainee must use the same anatomic and radiographic references required during actual surgical procedures. Using the aforementioned techniques, we have created simulators for ventriculostomy, percutaneous stereotactic lesion procedure for trigeminal neuralgia, and spinal instrumentation. The design and implementation of these platforms are presented. The system has provided the residents an opportunity to understand and appreciate the complex 3-dimensional anatomy of the 3 neurosurgical procedures simulated. The systems have also provided an opportunity to break procedures down into critical segments, allowing the user to concentrate on specific areas of deficiency.

  12. Procedural Modeling for Digital Cultural Heritage

    Directory of Open Access Journals (Sweden)

    Müller Pascal

    2009-01-01

    Full Text Available The rapid development of computer graphics and imaging provides the modern archeologist with several tools to realistically model and visualize archeological sites in 3D. This, however, creates a tension between veridical and realistic modeling. Visually compelling models may lead people to falsely believe that there exists very precise knowledge about the past appearance of a site. In order to make the underlying uncertainty visible, it has been proposed to encode this uncertainty with different levels of transparency in the rendering, or of decoloration of the textures. We argue that procedural modeling technology based on shape grammars provides an interesting alternative to such measures, as they tend to spoil the experience for the observer. Both its efficiency and compactness make procedural modeling a tool to produce multiple models, which together sample the space of possibilities. Variations between the different models express levels of uncertainty implicitly, while letting each individual model keeping its realistic appearance. The underlying, structural description makes the uncertainty explicit. Additionally, procedural modeling also yields the flexibility to incorporate changes as knowledge of an archeological site gets refined. Annotations explaining modeling decisions can be included. We demonstrate our procedural modeling implementation with several recent examples.

  13. A pebble count procedure for assessing watershed cumulative effects

    Science.gov (United States)

    Gregory S. Bevenger; Rudy M. King

    1995-01-01

    Land mangement activities can result in the delivery of fine sediment to streams. Over time, such delivery can lead to cumulative impacts to the aquactic ecosystem. Because numerous laws require Federal land managers to analyze watershed cumulative effects, field personnel need simple monitoring procedures that can be used directly and consistently. One approach to...

  14. Recent advances in numerical PDEs

    Science.gov (United States)

    Zuev, Julia Michelle

    In this thesis, we investigate four neighboring topics, all in the general area of numerical methods for solving Partial Differential Equations (PDEs). Topic 1. Radial Basis Functions (RBF) are widely used for multi-dimensional interpolation of scattered data. This methodology offers smooth and accurate interpolants, which can be further refined, if necessary, by clustering nodes in select areas. We show, however, that local refinements with RBF (in a constant shape parameter [varepsilon] regime) may lead to the oscillatory errors associated with the Runge phenomenon (RP). RP is best known in the case of high-order polynomial interpolation, where its effects can be accurately predicted via Lebesgue constant L (which is based solely on the node distribution). We study the RP and the applicability of Lebesgue constant (as well as other error measures) in RBF interpolation. Mainly, we allow for a spatially variable shape parameter, and demonstrate how it can be used to suppress RP-like edge effects and to improve the overall stability and accuracy. Topic 2. Although not as versatile as RBFs, cubic splines are useful for interpolating grid-based data. In 2-D, we consider a patch representation via Hermite basis functions s i,j ( u, v ) = [Special characters omitted.] h mn H m ( u ) H n ( v ), as opposed to the standard bicubic representation. Stitching requirements for the rectangular non-equispaced grid yield a 2-D tridiagonal linear system AX = B, where X represents the unknown first derivatives. We discover that the standard methods for solving this NxM system do not take advantage of the spline-specific format of the matrix B. We develop an alternative approach using this specialization of the RHS, which allows us to pre-compute coefficients only once, instead of N times. MATLAB implementation of our fast 2-D cubic spline algorithm is provided. We confirm analytically and numerically that for large N ( N > 200), our method is at least 3 times faster than the

  15. Direct Numerical Simulation and Visualization of Subcooled Pool Boiling

    Directory of Open Access Journals (Sweden)

    Tomoaki Kunugi

    2014-01-01

    Full Text Available A direct numerical simulation of the boiling phenomena is one of the promising approaches in order to clarify their heat transfer characteristics and discuss the mechanism. During these decades, many DNS procedures have been developed according to the recent high performance computers and computational technologies. In this paper, the state of the art of direct numerical simulation of the pool boiling phenomena during mostly two decades is briefly summarized at first, and then the nonempirical boiling and condensation model proposed by the authors is introduced into the MARS (MultiInterface Advection and Reconstruction Solver developed by the authors. On the other hand, in order to clarify the boiling bubble behaviors under the subcooled conditions, the subcooled pool boiling experiments are also performed by using a high speed and high spatial resolution camera with a highly magnified telescope. Resulting from the numerical simulations of the subcooled pool boiling phenomena, the numerical results obtained by the MARS are validated by being compared to the experimental ones and the existing analytical solutions. The numerical results regarding the time evolution of the boiling bubble departure process under the subcooled conditions show a very good agreement with the experimental results. In conclusion, it can be said that the proposed nonempirical boiling and condensation model combined with the MARS has been validated.

  16. The development of numerical representations in early childhood

    Directory of Open Access Journals (Sweden)

    Matija Svetina

    2011-01-01

    Full Text Available Recent studies of numerosity in the field of developmental psychology indicate that numerical representation in children might be regarded in terms of Fechner's law of logarithmic relations between stimuli and response. The data also suggest that the shift from logarithmic to linear pattern of mental representation relates to different factors such as age, number scale, and culture. However, very little is known whether cognitive factors such as procedural and conceptual development have any impact on numerical representations, particularly in the preschoolers. The aim of our study was to provide an explanation of relations between numerical concepts and numerical representations in preschool children. In the study, 39 3-6 year-olds were presented with both, task of conceptual understanding of numbers and the number line task. The results indicate that the development of conceptual understanding of numbers may act as a threshold condition to the development of linear numerical representations in early childhood. Implications of these findings, such as representations of height, distance or value are further discussed.

  17. Coal pillar design procedures

    CSIR Research Space (South Africa)

    York, G

    2000-03-01

    Full Text Available Final Project Report Coal pillar design procedures G. York, I. Canbulat, B.W. Jack Research agency: CSIR Mining Technology Project number: COL 337 Date: March 2000 2 Executive Summary Examination of collapsed pillar cases outside of the empirical... in strength occurs with increasing specimen size. 45 40 35 30 25 20 15 10 5 0 20 40 60 80 100 120 140 160 UNIAX IA L COMPR EHEN SIV E S TR ENG TH (M Pa ) CUBE SIZE (cm) Figure 1...

  18. A Major Step in the Harmonization of Procedural Law in Europe: The European Small Claims Procedure : Accomplishments, New Features and Some Fundamental Questions of European Harmonization

    NARCIS (Netherlands)

    X.E. Kramer (Xandra)

    2008-01-01

    textabstractEuropean civil procedural law has been in a constant state of flux since the coming into force of the Treaty of Amsterdam in 1999. The introduction of Article 65 EC Treaty was followed by numerous Community instruments in the field of civil procedure, mostly regulations that have direct

  19. Is the rapid adaptation paradigm too rapid? Implications for face and object processing.

    Science.gov (United States)

    Nemrodov, Dan; Itier, Roxane J

    2012-07-16

    Rapid adaptation is an adaptation procedure in which adaptors and test stimuli are presented in rapid succession. The current study tested the validity of this method for early ERP components by investigating the specificity of the adaptation effect on the face-sensitive N170 ERP component across multiple test stimuli. Experiments 1 and 2 showed identical response patterns for house and upright face test stimuli using the same adaptor stimuli. The results were also identical to those reported in a previous study using inverted face test stimuli (Nemrodov and Itier, 2011). In Experiment 3 all possible adaptor-test combinations between upright face, house, chair and car stimuli were used and no interaction between adaptor and test category, expected in the case of test-specific adaptation, was found. These results demonstrate that the rapid adaptation paradigm does not produce category-specific adaptation effects around 170-200 ms following test stimulus onset, a necessary condition for the interpretation of adaptation results. These results suggest the rapid categorical adaptation paradigm does not work. Copyright © 2012 Elsevier Inc. All rights reserved.

  20. Rapid climate change: lessons from the recent geological past

    Science.gov (United States)

    Holmes, Jonathan; Lowe, John; Wolff, Eric; Srokosz, Meric

    2011-12-01

    Rapid, or abrupt, climate change is regarded as a change in the climate system to a new state following the crossing of a threshold. It generally occurs at a rate exceeding that of the change in the underlying cause. Episodes of rapid climate change abound in the recent geological past (defined here as the interval between the last glacial maximum, dated to approximately 20,000 years ago, and the present). Rapid climate changes are known to have occurred over time periods equal to or even less than a human lifespan: moreover, their effects on the global system are sufficiently large to have had significant societal impacts. The potential for similar events to occur in the future provides an important impetus for investigating the nature and causes of rapid climate change. This paper provides a brief overview of rapid climate change and an introduction to this special issue, which presents results generated by the palaeoclimatic component of the UK Natural Environment Research Council's rapid climate change programme, called RAPID. The papers in the special issue employ palaeoclimatic proxy data-sets obtained from marine, ice core and terrestrial archives to reconstruct rapid climate change during the last glacial cycle, its subsequent termination and the ensuing Holocene interglacial; some papers also report new attempts to match the palaeoclimate data to hypothesised causes through numerical modelling. The results confirm the importance of freshwater forcing in triggering changes in Atlantic meridional overturning circulation (MOC) and the close links between MOC and rapid climate change. While advancing our understanding of these linkages, the RAPID research has highlighted the need for further research in order to elucidate more specific details of the mechanisms involved.

  1. Rapid prototyping in medical sciences

    Directory of Open Access Journals (Sweden)

    Ákos Márk Horváth

    2015-09-01

    Full Text Available Even if it sound a bit incredible rapid prototyping (RPT as production method has been used for decades in other professions. Nevertheless medical science just started discover the possibilities of this technology and use the offered benefits of 3D printing. In this paper authors have investigated the pharmaceutical usage of rapid prototyping.

  2. Regulations and Procedures Manual

    Energy Technology Data Exchange (ETDEWEB)

    Young, Lydia J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2011-07-25

    The purpose of the Regulations and Procedures Manual (RPM) is to provide LBNL personnel with a reference to University and Lawrence Berkeley National Laboratory (LBNL or Laboratory) policies and regulations by outlining normal practices and answering most policy questions that arise in the day-to-day operations of Laboratory organizations. Much of the information in this manual has been condensed from detail provided in LBNL procedure manuals, Department of Energy (DOE) directives, and Contract DE-AC02-05CH11231. This manual is not intended, however, to replace any of those documents. RPM sections on personnel apply only to employees who are not represented by unions. Personnel policies pertaining to employees represented by unions may be found in their labor agreements. Questions concerning policy interpretation should be directed to the LBNL organization responsible for the particular policy. A link to the Managers Responsible for RPM Sections is available on the RPM home page. If it is not clear which organization is responsible for a policy, please contact Requirements Manager Lydia Young or the RPM Editor.

  3. Regulations and Procedures Manual

    Energy Technology Data Exchange (ETDEWEB)

    Young, Lydia [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2010-09-30

    The purpose of the Regulations and Procedures Manual (RPM) is to provide Laboratory personnel with a reference to University and Lawrence Berkeley National Laboratory policies and regulations by outlining the normal practices and answering most policy questions that arise in the day-to-day operations of Laboratory departments. Much of the information in this manual has been condensed from detail provided in Laboratory procedure manuals, Department of Energy (DOE) directives, and Contract DE-AC02-05CH11231. This manual is not intended, however, to replace any of those documents. The sections on personnel apply only to employees who are not represented by unions. Personnel policies pertaining to employees represented by unions may be found in their labor agreements. Questions concerning policy interpretation should be directed to the department responsible for the particular policy. A link to the Managers Responsible for RPM Sections is available on the RPM home page. If it is not clear which department should be called, please contact the Associate Laboratory Director of Operations.

  4. Regulation and safe adoption of new medical devices and procedures.

    Science.gov (United States)

    Campbell, Bruce

    2013-01-01

    Recent problems with medical devices have highlighted the need for improved surveillance. New procedures are largely unregulated. Information from regulators. Guidance produced by the National Institute for Health and Care Excellence Interventional Procedures and Medical Technologies Advisory Committees and the evidence used in their evaluations. More and better evidence is required for new medical devices and procedures when they are introduced into practice. Routine collection of observational data on outcomes should be improved. How best to protect patients from harm while allowing rapid access to potentially beneficial interventions. Establishing systems for good data collection on the use of devices and procedures. How to accrue more and better evidence about devices and procedures through clinical trials and various avenues of observational data collection.

  5. Numerical simulation of endovenous laser treatment of the incompetent great saphenous vein with external air cooling.

    Science.gov (United States)

    Marqa, Mohamad Feras; Mordon, Serge; Hernández-Osma, Esteban; Trelles, Mario; Betrouni, Nacim

    2013-05-01

    Endovenous laser treatment (ELT) has been proposed as an alternative in the treatment of reflux of the great saphenous vein. Before the procedure, peri-saphenous subcutaneous tumescent saline solution infiltration is usually performed. However, diffusion of this tumescent fluid is rapidly observed and can potentially reduce the efficacy as a heat sink. External skin cooling with cold air was proposed as an alternative solution. The objective of this study is to compare endovenous laser treatment without and with air cooling by realistic numerical simulations. An optical-thermal damage model was formulated and implemented using finite element modeling. The general model simulated light distribution using the diffusion approximation of the transport theory, temperature rise using the bioheat equation, and laser-induced injury using the Arrhenius damage model. Parameters, used in clinical procedures, were considered: power, 15 W; pulse duration, 1 s; fiber pull back, 3-mm increments every second; cold air applied in continuous mode during ELT; and no tumescent anesthesia. Simulations were performed for vein locations at 5, 10, and 15 mm in depth, with and without air cooling. For a vein located at 15 mm in depth, no significant difference was observed with and without cooling. For a vein located at 10 mm in depth, surface temperature increase up to 45 °C is observed without cooling. For a vein located at 5 mm, without cooling, temperature increase leads to irreversible damage of dermis and epidermis. Conversely, with air cooling, surface temperature reaches a maximum of 38 °C in accordance with recordings performed on patients. ELT of the incompetent great saphenous vein with external air cooling system is a promising therapy technique. Use of cold air on the skin continuously flowing in the area of laser shot decreased significantly the heat extent and the thermal damage in the perivenous tissues and the skin.

  6. Modified Ravitch procedure: a customized solution for iatrogenic ...

    African Journals Online (AJOL)

    Skeletal deformities in the form of pectus excavatum or scoliosis are unavoidable sequalae of large diaphragmmatic defects irrespective of the technique of repair used at the time of primary procedure. These sequelae lead to cosmetic and functional issues in the rapidly growing skeleton of a young child. The crux of.

  7. Disruptive Innovation in Numerical Hydrodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Waltz, Jacob I. [Los Alamos National Laboratory

    2012-09-06

    We propose the research and development of a high-fidelity hydrodynamic algorithm for tetrahedral meshes that will lead to a disruptive innovation in the numerical modeling of Laboratory problems. Our proposed innovation has the potential to reduce turnaround time by orders of magnitude relative to Advanced Simulation and Computing (ASC) codes; reduce simulation setup costs by millions of dollars per year; and effectively leverage Graphics Processing Unit (GPU) and future Exascale computing hardware. If successful, this work will lead to a dramatic leap forward in the Laboratory's quest for a predictive simulation capability.

  8. Numerical Relativity and Asymptotic Flatness

    OpenAIRE

    Deadman, E.; Stewart, J. M.

    2009-01-01

    It is highly plausible that the region of space-time far from an isolated gravitating body is, in some sense, asymptotically Minkowskian. However theoretical studies of the full nonlinear theory, initiated by Bondi et al. (1962), Sachs (1962) and Newman & Unti (1962), rely on careful, clever, a-priori choices of chart (and tetrad) and so are not readily accessible to the numerical relativist, who chooses her/his chart on the basis of quite different grounds. This paper seeks to close this gap...

  9. Numerical Solution of Parabolic Equations

    DEFF Research Database (Denmark)

    Østerby, Ole

    These lecture notes are designed for a one-semester course on finite-difference methods for parabolic equations. These equations which traditionally are used for describing diffusion and heat-conduction problems in Geology, Physics, and Chemistry have recently found applications in Finance Theory...... approximations which depend on a step size, such as numerical integration and solution of ordinary and partial differential equations. An integral part of the error estimation is the estimation of the order of the method and can thus satisfy the inquisitive mind: Is the order what we expect it to be from theopry...

  10. Numerical methods for multibody systems

    Science.gov (United States)

    Glowinski, Roland; Nasser, Mahmoud G.

    1994-01-01

    This article gives a brief summary of some results obtained by Nasser on modeling and simulation of inequality problems in multibody dynamics. In particular, the augmented Lagrangian method discussed here is applied to a constrained motion problem with impulsive inequality constraints. A fundamental characteristic of the multibody dynamics problem is the lack of global convexity of its Lagrangian. The problem is transformed into a convex analysis problem by localization (piecewise linearization), where the augmented Lagrangian has been successfully used. A model test problem is considered and a set of numerical experiments is presented.

  11. Results from Numerical General Relativity

    Science.gov (United States)

    Baker, John G.

    2011-01-01

    For several years numerical simulations have been revealing the details of general relativity's predictions for the dynamical interactions of merging black holes. I will review what has been learned of the rich phenomenology of these mergers and the resulting gravitational wave signatures. These wave forms provide a potentially observable record of the powerful astronomical events, a central target of gravitational wave astronomy. Asymmetric radiation can produce a thrust on the system which may accelerate the single black hole resulting from the merger to high relative velocity.

  12. The Hindu-Arabic numerals

    CERN Document Server

    Smith, David Eugene

    1911-01-01

    The numbers that we call Arabic are so familiar throughout Europe and the Americas that it can be difficult to realize that their general acceptance in commercial transactions is a matter of only the last four centuries and they still remain unknown in parts of the world.In this volume, one of the earliest texts to trace the origin and development of our number system, two distinguished mathematicians collaborated to bring together many fragmentary narrations to produce a concise history of Hindu-Arabic numerals. Clearly and succinctly, they recount the labors of scholars who have studied the

  13. On Spurious Numerics in Solving Reactive Equations

    Science.gov (United States)

    Kotov, D. V; Yee, H. C.; Wang, W.; Shu, C.-W.

    2013-01-01

    The objective of this study is to gain a deeper understanding of the behavior of high order shock-capturing schemes for problems with stiff source terms and discontinuities and on corresponding numerical prediction strategies. The studies by Yee et al. (2012) and Wang et al. (2012) focus only on solving the reactive system by the fractional step method using the Strang splitting (Strang 1968). It is a common practice by developers in computational physics and engineering simulations to include a cut off safeguard if densities are outside the permissible range. Here we compare the spurious behavior of the same schemes by solving the fully coupled reactive system without the Strang splitting vs. using the Strang splitting. Comparison between the two procedures and the effects of a cut off safeguard is the focus the present study. The comparison of the performance of these schemes is largely based on the degree to which each method captures the correct location of the reaction front for coarse grids. Here "coarse grids" means standard mesh density requirement for accurate simulation of typical non-reacting flows of similar problem setup. It is remarked that, in order to resolve the sharp reaction front, local refinement beyond standard mesh density is still needed.

  14. Numerical simulations of pulsejet engines

    Science.gov (United States)

    Geng, Tao

    The pulsejet has recently received more research interests due to its simple design, which can be developed into low-cost micro-scale propulsion devices for use in many of today's new applications such as UAVs. However, the relatively low thermal efficiency of pulsejets has always been the major obstacle in their development. The goal of this research is to investigate the possibility of using pulsejets in certain applications where the pulsejet can trade its low efficiency with low cost, simple design, and light weight. This work investigates pulsejet operation in a combined experimental and numerical approach, although the focus here is on the computational research. The fluid mechanics, acoustics, and chemical kinetics are studied numerically to understand the physics behind pulsejets and their operations. The research objectives include miniaturization of valveless pulsejets, acoustics model developments for both valved and valveless pulsejets, obtaining preliminary thrust performance data on micro-scale pulsejets, and finally, the formation of the starting vortex ring and its effect on pulsejet thrust.

  15. Uncertainty Quantification in Numerical Aerodynamics

    KAUST Repository

    Litvinenko, Alexander

    2017-05-16

    We consider uncertainty quantification problem in aerodynamic simulations. We identify input uncertainties, classify them, suggest an appropriate statistical model and, finally, estimate propagation of these uncertainties into the solution (pressure, velocity and density fields as well as the lift and drag coefficients). The deterministic problem under consideration is a compressible transonic Reynolds-averaged Navier-Strokes flow around an airfoil with random/uncertain data. Input uncertainties include: uncertain angle of attack, the Mach number, random perturbations in the airfoil geometry, mesh, shock location, turbulence model and parameters of this turbulence model. This problem requires efficient numerical/statistical methods since it is computationally expensive, especially for the uncertainties caused by random geometry variations which involve a large number of variables. In numerical section we compares five methods, including quasi-Monte Carlo quadrature, polynomial chaos with coefficients determined by sparse quadrature and gradient-enhanced version of Kriging, radial basis functions and point collocation polynomial chaos, in their efficiency in estimating statistics of aerodynamic performance upon random perturbation to the airfoil geometry [D.Liu et al \\'17]. For modeling we used the TAU code, developed in DLR, Germany.

  16. Numerical Hydrodynamics in Special Relativity.

    Science.gov (United States)

    Martí, José Maria; Müller, Ewald

    2003-01-01

    This review is concerned with a discussion of numerical methods for the solution of the equations of special relativistic hydrodynamics (SRHD). Particular emphasis is put on a comprehensive review of the application of high-resolution shock-capturing methods in SRHD. Results of a set of demanding test bench simulations obtained with different numerical SRHD methods are compared. Three applications (astrophysical jets, gamma-ray bursts and heavy ion collisions) of relativistic flows are discussed. An evaluation of various SRHD methods is presented, and future developments in SRHD are analyzed involving extension to general relativistic hydrodynamics and relativistic magneto-hydrodynamics. The review further provides FORTRAN programs to compute the exact solution of a 1D relativistic Riemann problem with zero and nonzero tangential velocities, and to simulate 1D relativistic flows in Cartesian Eulerian coordinates using the exact SRHD Riemann solver and PPM reconstruction. Supplementary material is available for this article at 10.12942/lrr-2003-7 and is accessible for authorized users.

  17. Arithmetics in β-numeration

    Directory of Open Access Journals (Sweden)

    Julien Bernat

    2007-01-01

    Full Text Available The β-numeration, born with the works of Rényi and Parry, provides a generalization of the notions of integers, decimal numbers and rational numbers by expanding real numbers in base β, where β>1 is not an integer. One of the main differences with the case of numeration in integral base is that the sets which play the role of integers, decimal numbers and rational numbers in base β are not stable under addition or multiplication. In particular, a fractional part may appear when one adds or multiplies two integers in base β. When β is a Pisot number, which corresponds to the most studied case, the lengths of the finite fractional parts that may appear when one adds or multiplies two integers in base β are bounded by constants which only depend on β. We prove that, for any Perron number β, the set of finite or ultimately periodic fractional parts of the sum, or the product, of two integers in base β is finite. Additionally, we prove that it is possible to compute this set for the case of addition when β is a Parry number. As a consequence, we deduce that, when β is a Perron number, there exist bounds, which only depend on β, for the lengths of the finite fractional parts that may appear when one adds or multiplies two integers in base β. Moreover, when β is a Parry number, the bound associated with the case of addition can be explicitly computed.

  18. Numerical Propulsion System Simulation Architecture

    Science.gov (United States)

    Naiman, Cynthia G.

    2004-01-01

    The Numerical Propulsion System Simulation (NPSS) is a framework for performing analysis of complex systems. Because the NPSS was developed using the object-oriented paradigm, the resulting architecture is an extensible and flexible framework that is currently being used by a diverse set of participants in government, academia, and the aerospace industry. NPSS is being used by over 15 different institutions to support rockets, hypersonics, power and propulsion, fuel cells, ground based power, and aerospace. Full system-level simulations as well as subsystems may be modeled using NPSS. The NPSS architecture enables the coupling of analyses at various levels of detail, which is called numerical zooming. The middleware used to enable zooming and distributed simulations is the Common Object Request Broker Architecture (CORBA). The NPSS Developer's Kit offers tools for the developer to generate CORBA-based components and wrap codes. The Developer's Kit enables distributed multi-fidelity and multi-discipline simulations, preserves proprietary and legacy codes, and facilitates addition of customized codes. The platforms supported are PC, Linux, HP, Sun, and SGI.

  19. Numerical Modeling of Munroe Jets

    Science.gov (United States)

    Mader, Charles; Gittings, Michael

    2007-06-01

    Munroe jets are formed by the oblique interaction of detonation products from two explosive charges separated by an air gap. The jet consists of a high velocity jet of low density precursor gases and particles that travel faster than the primary jet which is a high pressure regular shock reflection. The Los Alamos PHERMEX Data Volumes [1] contain 40 radiographs taken by Douglas Venable in the 1960's of Munroe Jets generated by Composition B explosive charges separated by 5 to 80 mm of air. In several of the experiments the Munroe jets interacted with thin Tantalum foils and with aluminum plates. The PHERMEX experiments were modeled using the AMR Eulerian reactive hydrodynamic code, NOBEL [2,3], When the detonation arrives at the bottom of the gap, the detonation product s expand against the air and precursor gases travel at high velocity ahead of the detonation wave in the explosive. The expanding detonation products from the explosive collide and result in a high pressure regular shock reflection.. Interaction with a metal plate consists of first the interaction of the precursor gases and then the high pressure regular shock reflection arrives to further damage the metal plate. [1] Los Alamos PHERMEX Data, Volumes I, II, and III, UC Press 1980. [2] Numerical Modeling of Water Waves, Second Edition, Charles L. Mader, CRC Press 2004 [3] Numerical Modeling of Explosions and Propellants, Charles L. Mader, CRC Press 1998.

  20. Numerical Model for Hydrovolcanic Explosions.

    Science.gov (United States)

    Mader, Charles; Gittings, Michael

    2007-03-01

    A hydrovolcanic explosion is generated by the interaction of hot magma with ground water. It is called Surtseyan after the 1963 explosive eruption off Iceland. The water flashes to steam and expands explosively. Liquid water becomes water gas at constant volume and generates pressures of about 3GPa. The Krakatoa hydrovolcanic explosion was modeled using the full Navier-Stokes AMR Eulerian compressible hydrodynamic code called SAGE [1] which includes the high pressure physics of explosions. The water in the hydrovolcanic explosion was described as liquid water heated by magma to 1100 K. The high temperature water is treated as an explosive with the hot liquid water going to water gas. The BKW [2] steady state detonation state has a peak pressure of 8.9 GPa, a propagation velocity of 5900 meters/sec and the water is compressed to 1.33 g/cc. [1] Numerical Modeling of Water Waves, Second Edition, Charles L. Mader, CRC Press 2004. [2] Numerical Modeling of Explosions and Propellants, Charles L. Mader, CRC Press 1998.

  1. Interface dynamics and banding in rapid solidification

    Energy Technology Data Exchange (ETDEWEB)

    Karma, A.; Sarkissian, A. (Physics Department, Northeastern University, Boston, Massachusetts 02115 (United States))

    1993-01-01

    Rapid-solidification experiments on metallic alloys in the last decade have provided widespread observations of a novel banded structure.'' We report the results of numerical and analytical studies of the interface dynamics underlying the formation of this structure in a model of directional solidification which includes both solute and heat diffusion and nonequilibrium effects. The thrust of these studies is on the unsteady dynamics of the planar interface and thermal effects. The main conclusion is that the origin of banding can be related to relaxation oscillations of the solidification front, characterized by large variations of the interface velocity, which are dramatically affected by latent-heat diffusion. Without the latter, the oscillations are found to be reasonably well approximated by the phenomenological model of Carrard [ital et] [ital al]. [Acta Metall. 40, 983 (1992)], and the band spacing is inversely proportional to the temperature gradient. In contrast, with latent-heat diffusion the band spacing is insensitive to the temperature gradient, but is controlled instead by the interplay of solute and heat diffusion. The smallness of the solutal diffusivity to thermal diffusivity ratio is exploited to explain analytically this effect and to derive considerably simpler equations of interface motion that provide an efficient numerical means to study the nonplanar interface dynamics expected to cause dark bands. A reasonable agreement with experiment is found for the spacing of banded structures dominated by light-band microsegregation-free regions in Al-Fe alloys.

  2. Radiotherapic procedures in vulvar carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Cintra e Oliveira, V. (Hospital dos Servidores Publicos de Sao Paulo (Brazil); Instituto de Radioterapia de Sao Paulo (Brazil)); Lima, G.R. de (Escola Paulista de Medicina, Sao Paulo (Brazil); Hospital dos Servidores Publicos de Sao Paulo (Brazil)); Peres, O. (Instituto de Radioterapia de Sao Paulo (Brazil))

    The cases of six patients with vulvar squamous carcinoma are discussed. The radiotherapic procedure employed in the treatment is presented and compared to other methods. The small morbidity of the therapeutic procedure followed is commented.

  3. FastStats: Obstetrical Procedures

    Science.gov (United States)

    ... Whooping Cough or Pertussis Family Life Marriage and Divorce Health Care and Insurance Access to Health Care ... Survey: 2010 table, Procedures by selected patient characteristics - Rate by procedure category and age [PDF - 168 KB] ...

  4. UV irradiance radiometers calibration procedure

    OpenAIRE

    Doctorovich I. V.; Butenko V. K.; Hodovaniouk V. N.; Fodchuk I. M.; Yuriev V. G.

    2008-01-01

    The paper deals with the problems arising at calibration of narrow-band spectral-sensitive radiometers. The procedure of irradiance unit transfer to UV radiometers — UV radiometers calibration procedure — is presented.

  5. Robust procedures in chemometrics

    DEFF Research Database (Denmark)

    Kotwa, Ewelina

    and comparing the Partial Least Squares (PLS) regression technique with its multi-way alternative, N-PLS. Results of the analysis indicated superiority of the three-way frame-work, potentially constituting a novel assessment of the sea water measurements. Particularly in the case of regression models......The general aim of the thesis was to contribute to the improvement of data analytical techniques within the chemometric field. Regardless the multivariate structure of the data, it is still common in some fields to perform uni-variate data analysis using only simple statistics such as sample mean...... if contamination in the data is present. For this becoming a standard procedure, further work is required, aiming at implementing reliable robust algorithms into standard statistical programs....

  6. How Rapid is Rapid Prototyping? Analysis of ESPADON Programme Results

    Directory of Open Access Journals (Sweden)

    Ian D. Alston

    2003-05-01

    Full Text Available New methodologies, engineering processes, and support environments are beginning to emerge for embedded signal processing systems. The main objectives are to enable defence industry to field state-of-the-art products in less time and with lower costs, including retrofits and upgrades, based predominately on commercial off the shelf (COTS components and the model-year concept. One of the cornerstones of the new methodologies is the concept of rapid prototyping. This is the ability to rapidly and seamlessly move from functional design to the architectural design to the implementation, through automatic code generation tools, onto real-time COTS test beds. In this paper, we try to quantify the term “rapid” and provide results, the metrics, from two independent benchmarks, a radar and sonar beamforming application subset. The metrics show that the rapid prototyping process may be sixteen times faster than a conventional process.

  7. Experiments on rapidly-sheared wall turbulence

    Science.gov (United States)

    Diwan, Sourabh; Morrison, Jonathan

    2013-11-01

    The use of linear theories in wall turbulence dates back to Townsend (1976, Cambridge University Press) who extensively used Rapid Distortion Theory (RDT) for understanding the structure of near-wall turbulence. Various other linear tools have been used in more recent investigations. The present study is an attempt to further explore this aspect and is in part motivated by the recent numerical work of Sharma et al. (Phys. Fluids 23, 2011) that highlighted the possible role of linear mechanisms in wall turbulence. Our experimental arrangement involves passing a grid-generated turbulent flow over a flat plate mounted downstream of the grid in a wind tunnel. The grid turbulence is subjected to large rates of shear strain by the wall layer close to the leading edge of the plate and as a result, over a certain region in its vicinity, the approximations of the RDT can be expected to be approximately satisfied. We present detailed single-point and planar velocity measurements, and pressure measurements using surface-mounted pressure transducers, the aim being to establish a turbulent wall layer in which linear processes are dominant. Such a flow can be used to evaluate the ideas relating to linear theories of Townsend and Landahl, among others. We also present the structural changes that take place as the rapidly-sheared wall layer evolves towards a more conventional boundary layer further downstream. We acknowledge financial support from EPSRC under Grant No. EP/I037938.

  8. Quantization Procedures; Sistemas de cuantificacion

    Energy Technology Data Exchange (ETDEWEB)

    Cabrera, J. A.; Martin, R.

    1976-07-01

    We present in this work a review of the conventional quantization procedure, the proposed by I.E. Segal and a new quantization procedure similar to this one for use in non linear problems. We apply this quantization procedures to different potentials and we obtain the appropriate equations of motion. It is shown that for the linear case the three procedures exposed are equivalent but for the non linear cases we obtain different equations of motion and different energy spectra. (Author) 16 refs.

  9. The Wallops Flight Facility Rapid Response Range Operations Initiative

    Science.gov (United States)

    Underwood, Bruce E.; Kremer, Steven E.

    2004-01-01

    becomes how can a launch site provide acceptably responsive mission services to a particular customer without dedicating extensive resources and while continuing to serve other projects? NASA's Wallops Flight Facility (WFF) is pursuing solutions to exactly this challenge. NASA, in partnership with the Virginia Commercial Space Flight Authority, has initiated the Rapid Response Range Operations Initiative (R3Ops). R3Ops is a multi-phased effort to incrementally establish and demonstrate increasingly responsive launch operations, with an ultimate goal of providing ELV-class services in a maximum of 7-10 days from initial notification routinely, and shorter schedules possible with committed resources. This target will be pursued within the reality of simultaneous concurrent programs, and ideally, largely independent of specialized flight system configurations. WFF has recently completed Phase 1 of R3Ops, an in-depth collection (through extensive expert interviews) and software modeling of individual steps by various range disciplines. This modeling is now being used to identify existing inefficiencies in current procedures, to identify bottlenecks, and show interdependencies. Existing practices are being tracked to provide a baseline to benchmark against as new procedures are implemented. This paper will describe in detail the philosophies behind WFF's R3Ops, the data collected and modeled in Phase 1, and strategies for meeting responsive launch requirements in a multi-user range environment planned for subsequent phases of this initiative.

  10. Rapid surface sampling and archival record system

    Energy Technology Data Exchange (ETDEWEB)

    Barren, E.; Penney, C.M.; Sheldon, R.B. [GE Corporate Research and Development Center, Schenectady, NY (United States)] [and others

    1995-10-01

    A number of contamination sites exist in this country where the area and volume of material to be remediated is very large, approaching or exceeding 10{sup 6} m{sup 2} and 10{sup 6} m{sup 3}. Typically, only a small fraction of this material is actually contaminated. In such cases there is a strong economic motivation to test the material with a sufficient density of measurements to identify which portions are uncontaminated, so extensively they be left in place or be disposed of as uncontaminated waste. Unfortunately, since contamination often varies rapidly from position to position, this procedure can involve upwards of one million measurements per site. The situation is complicated further in many cases by the difficulties of sampling porous surfaces, such as concrete. This report describes a method for sampling concretes in which an immediate distinction can be made between contaminated and uncontaminated surfaces. Sample acquisition and analysis will be automated.

  11. Skin simulators for dermatological procedures

    OpenAIRE

    Wang, Xiaojie; Albahrani, Yasser; Pan, Michael; Levitt, Jacob

    2015-01-01

    Background: A variety of skin simulators are available on which to practice procedures; however, choice of a suboptimal substitute compromises realism and productive practice. Objective: Skin simulators for basic dermatological procedures are reviewed. Methods: The authors’ anecdotal experience with various skin simulators for different procedures is shared. Results: The following simulators are suggested:  an unripe banana ...

  12. Developments in European Civil Procedures

    NARCIS (Netherlands)

    Cortés, P.; Mańko, R.; Cortés, P.

    2016-01-01

    This chapter is structured as follows. In Section B we explore the legal basis for the creation of European civil procedures and Europeanization of procedural private law in general. In Section C we provide an overview of existing EU instruments on civil procedure, which we propose to divide into

  13. Nursing Procedures. NAVMED P-5066.

    Science.gov (United States)

    Bureau of Medicine and Surgery (Navy), Washington, DC.

    The revised manual of nursing procedures covers fundamental nursing care, admission and discharge of the patient, assisting with therapeutic measures, pre- and postoperative care, diagnostic tests and procedures, and isolation technique. Each of the over 300 topics includes the purpose, equipment, and procedure to be used and, where relevant, such…

  14. Homogenization-Based Numerical Mathods, Homogenization, Asymptotic Analysis, Asymptotic Expansion, Numerical Simulation

    OpenAIRE

    Frenod, Emmanuel

    2013-01-01

    In this note, a classification of Homogenization-Based Numerical Methods and (in particular) of Numerical Methods that are based on the Two-Scale Convergence is done. In this classification stand: Direct Homogenization-Based Numerical Methods; H-Measure-Based Numerical Methods; Two-Scale Numerical Methods and TSAPS: Two-Scale Asymptotic Preserving Schemes.

  15. 9 CFR 147.3 - The stained-antigen, rapid, whole-blood test. 3

    Science.gov (United States)

    2010-01-01

    ...-blood test. 3 147.3 Section 147.3 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... Blood Testing Procedures § 147.3 The stained-antigen, rapid, whole-blood test. 3 3 The procedure... necessary. The test plate should be rocked from side to side a few times to mix the antigen and blood...

  16. A Numerical Procedure for Model Identifiability Analysis Applied to Enzyme Kinetics

    DEFF Research Database (Denmark)

    Daele, Timothy, Van; Van Hoey, Stijn; Gernaey, Krist

    2015-01-01

    exercise, thereby bypassing the challenging task of model structure determination and identification. Parameter identification problems can thus lead to ill-calibrated models with low predictive power and large model uncertainty. Every calibration exercise should therefore be precededby a proper model...

  17. Determination of joint stiffness to improve numerical modelling methods for designing safer mining procedures

    CSIR Research Space (South Africa)

    Eve, R

    1994-11-01

    Full Text Available stream_source_info GAP101.pdf.txt stream_content_type text/plain stream_size 62 Content-Encoding ISO-8859-1 stream_name GAP101.pdf.txt Content-Type text/plain; charset=ISO-8859-1 ...

  18. A Numerical Procedure to Obtain the Creep Parameters of the Thermal Barrier Coating

    Directory of Open Access Journals (Sweden)

    Shifeng Wen

    2014-05-01

    Full Text Available Three-point bending creep test was used to understand the creep behavior of typical thin film/substrate systems—thermal barrier coating (TBC systems. Firstly, a simplified model, which does not consider the local effect, has been set up to get an analytical relationship. The important result is that creep stress exponent of materials is equal to the creep load exponent of the steady-state deflection rate of BC specimens. Secondly, in order to consider the local effect of bending, the finite element method (FEM has been carried out. FEM calculation shows that there is a steady stage of the creep deflection under a constant applied load. And the exponent of the steady-state creep deflection rate to the applied load is found to be equal to the creep stress exponent of materials. The creep constant of the materials can be obtained by a set of trials with assumed creep constants of materials and can be finally determined by the best fit method. Finally, the finite element results show that the influences of the friction, the thickness of TBCs, and the modulus ratio of TBC to the substrate on stress distribution are important.

  19. Overview of the numerical methods for the modelling of rock mechanics problems

    OpenAIRE

    Nikolić, Mijo; Roje-Bonacci, Tanja; Ibrahimbegović, Adnan

    2016-01-01

    The numerical methods have their origin in the early 1960s and even at that time it was noted that numerical methods can be successfully applied in various engineering and scientific fields, including the rock mechanics. Moreover, the rapid development of computers was a necessary background for solving computationally more demanding problems and the development process of the methods in general. Thus, we have many different methods presently, which can be separated into two main branches: co...

  20. Self-consistent viscous heating of rapidly compressed turbulence

    Science.gov (United States)

    Campos, Alejandro; Morgan, Brandon; Olson, Britton; Greenough, Jeffrey

    2016-11-01

    Given turbulence subjected to infinitely rapid deformations, linear terms representing interactions between the mean flow and the turbulence dictate the flow evolution, whereas non-linear terms corresponding to turbulence-turbulence interactions are safely ignored. For rapidly deformed flows where the turbulence Reynolds number is not sufficiently large, viscous effects can't be neglected and tend to play a prominent role, as shown in Davidovits & Fisch (2016). For such a case, the rapid increase of viscosity in a plasma-as compared to the weaker scaling of viscosity in a fluid-leads to the sudden viscous dissipation of turbulent kinetic energy. As described in Davidovits & Fisch, increases in temperature caused by the direct compression of the plasma drive sufficiently large values of viscosity. We report on numerical simulations of turbulence where the increase in temperature is the result of both the direct compression (an inviscid mechanism) and the self-consistent viscous transfer of energy from the turbulent scales towards the thermal energy. A comparison between implicit large-eddy simulations against well-resolved direct numerical simulations is included to asses the effect of the numerical and subgrid-scale dissipation on the self-consistent viscous energy transfer. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  1. Numerical optimization using flow equations.

    Science.gov (United States)

    Punk, Matthias

    2014-12-01

    We develop a method for multidimensional optimization using flow equations. This method is based on homotopy continuation in combination with a maximum entropy approach. Extrema of the optimizing functional correspond to fixed points of the flow equation. While ideas based on Bayesian inference such as the maximum entropy method always depend on a prior probability, the additional step in our approach is to perform a continuous update of the prior during the homotopy flow. The prior probability thus enters the flow equation only as an initial condition. We demonstrate the applicability of this optimization method for two paradigmatic problems in theoretical condensed matter physics: numerical analytic continuation from imaginary to real frequencies and finding (variational) ground states of frustrated (quantum) Ising models with random or long-range antiferromagnetic interactions.

  2. Numerical computation of Pop plot

    Energy Technology Data Exchange (ETDEWEB)

    Menikoff, Ralph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-23

    The Pop plot — distance-of-run to detonation versus initial shock pressure — is a key characterization of shock initiation in a heterogeneous explosive. Reactive burn models for high explosives (HE) must reproduce the experimental Pop plot to have any chance of accurately predicting shock initiation phenomena. This report describes a methodology for automating the computation of a Pop plot for a specific explosive with a given HE model. Illustrative examples of the computation are shown for PBX 9502 with three burn models (SURF, WSD and Forest Fire) utilizing the xRage code, which is the Eulerian ASC hydrocode at LANL. Comparison of the numerical and experimental Pop plot can be the basis for a validation test or as an aid in calibrating the burn rate of an HE model. Issues with calibration are discussed.

  3. Numerical Modeling of Microelectrochemical Systems

    DEFF Research Database (Denmark)

    Adesokan, Bolaji James

    reaction term at the boundary. We investigate the effect of flow rates, scan rates, and concentration on the cyclic voltammetry. We establish that high flow rates lead to the reduced hysteresis in the cyclic voltammetry curves and increasing scan rates lead to more pronounced current peaks. The final part...... incorporates the finite size of ionic species in the transport equation. The model presents a more appropriate boundary conditions which describe the modified Butler-Volmer reaction kinetics and account for the surface capacitance of the thin electric double layer. We also have found analytical solution...... of the paper shows that the response current in a cyclic voltammetry increases proportionally to the electrolyte concentration. In the second paper we present an experiment of an electrochemical system in a microfluidc system and compare the result to the numerical solutions. We investigate how the position...

  4. Physical and Relativistic Numerical Cosmology

    Directory of Open Access Journals (Sweden)

    Peter Anninos

    1998-01-01

    Full Text Available In order to account for the observable Universe, any comprehensive theory or model of cosmology must draw from many disciplines of physics, including gauge theories of strong and weak interactions, the hydrodynamics and microphysics of baryonic matter, electromagnetic fields, and spacetime curvature, for example. Although it is difficult to incorporate all these physical elements into a single complete model of our Universe, advances in computing methods and technologies have contributed significantly towards our understanding of cosmological models, the Universe, and astrophysical processes within them. A sample of numerical calculations addressing specific issues in cosmology are reviewed in this article: from the Big Bang singularity dynamics to the fundamental interactions of gravitational waves; from the quark--hadron phase transition to the large scale structure of the Universe. The emphasis, although not exclusively, is on those calculations designed to test different models of cosmology against the observed Universe.

  5. Non-Standard Numeration Systems

    Directory of Open Access Journals (Sweden)

    P. Ambrož

    2005-01-01

    Full Text Available We study some properties of non-standard numeration systems with an irrational base ß >1, based on the so-called beta-expansions of real numbers [1]. We discuss two important properties of these systems, namely the Finiteness property, stating whether the set of finite expansions in a given system forms a ring, and then the problem of fractional digits arising under arithmetic operations with integers in a given system. Then we introduce another way of irrational representation of numbers, slightly different from classical beta-expansions. Here we restrict ourselves to one irrational base – the golden mean ? – and we study the Finiteness property again. 

  6. Operator theory and numerical methods

    CERN Document Server

    Fujita, H; Suzuki, T

    2001-01-01

    In accordance with the developments in computation, theoretical studies on numerical schemes are now fruitful and highly needed. In 1991 an article on the finite element method applied to evolutionary problems was published. Following the method, basically this book studies various schemes from operator theoretical points of view. Many parts are devoted to the finite element method, but other schemes and problems (charge simulation method, domain decomposition method, nonlinear problems, and so forth) are also discussed, motivated by the observation that practically useful schemes have fine mathematical structures and the converses are also true. This book has the following chapters: 1. Boundary Value Problems and FEM. 2. Semigroup Theory and FEM. 3. Evolution Equations and FEM. 4. Other Methods in Time Discretization. 5. Other Methods in Space Discretization. 6. Nonlinear Problems. 7. Domain Decomposition Method.

  7. Numerical Modeling of Shoreline Undulations

    DEFF Research Database (Denmark)

    Kærgaard, Kasper Hauberg

    The present thesis considers undulations on sandy shorelines. The aim of the study is to determine the physical mechanisms which govern the morphologic evolution of shoreline undulations, and thereby to be able to predict their shape, dimensions and evolution in time. In order to do so a numerical...... undulations are described by the model. The shoreline evolution is considered for both constant and varying wave forcing and both periodic model domains with a single undulation as well as periodic model domains with multiple undulation are considered. Three different shoreline shapes are found depending...... of the shoreline. Thirdly the shoreline evolution model is tuned to two naturally occurring shorelines. On one of the shorelines, the west coast of Namibia, the shoreline model is able to describe the observed shoreline features in both a qualitative and quantitative way. The model over-predicts the scale...

  8. Relativistic Positioning Systems: Numerical Simulations

    CERN Document Server

    Puchades, Neus

    2014-01-01

    The motion of satellite constellations similar to GPS and Galileo is numerically simulated and, then, the region where bifurcation (double positioning) occurs is appropriately represented. In the cases of double positioning, the true location may be found using additional information (angles or times). The zone where the Jacobian, J, of the transformation from inertial to emission coordinates vanishes is also represented and interpreted. It is shown that the uncertainties in the satellite world lines produce positioning errors, which depend on the value of |J|. The smaller this quantity the greater the expected positioning errors. Among all the available 4-tuples of satellites, the most appropriate one -for a given location- should minimize positioning errors (large enough |J| values) avoiding bifurcation. Our study is particularly important to locate objects which are far away from Earth, e.g., satellites.

  9. Physical and Relativistic Numerical Cosmology.

    Science.gov (United States)

    Anninos, Peter

    1998-01-01

    In order to account for the observable Universe, any comprehensive theory or model of cosmology must draw from many disciplines of physics, including gauge theories of strong and weak interactions, the hydrodynamics and microphysics of baryonic matter, electromagnetic fields, and spacetime curvature, for example. Although it is difficult to incorporate all these physical elements into a single complete model of our Universe, advances in computing methods and technologies have contributed significantly towards our understanding of cosmological models, the Universe, and astrophysical processes within them. A sample of numerical calculations addressing specific issues in cosmology are reviewed in this article: from the Big Bang singularity dynamics to the fundamental interactions of gravitational waves; from the quark-hadron phase transition to the large scale structure of the Universe. The emphasis, although not exclusively, is on those calculations designed to test different models of cosmology against the observed Universe.

  10. Black-Hole Binaries, Gravitational Waves, and Numerical Relativity

    Science.gov (United States)

    Kelly, Bernard J.; Centrella, Joan; Baker, John G.; Kelly, Bernard J.; vanMeter, James R.

    2010-01-01

    Understanding the predictions of general relativity for the dynamical interactions of two black holes has been a long-standing unsolved problem in theoretical physics. Black-hole mergers are monumental astrophysical events ' releasing tremendous amounts of energy in the form of gravitational radiation ' and are key sources for both ground- and spacebased gravitational wave detectors. The black-hole merger dynamics and the resulting gravitational waveforms can only he calculated through numerical simulations of Einstein's equations of general relativity. For many years, numerical relativists attempting to model these mergers encountered a host of problems, causing their codes to crash after just a fraction of a binary orbit cnuld be simulated. Recently ' however, a series of dramatic advances in numerical relativity has ' for the first time, allowed stable / robust black hole merger simulations. We chronicle this remarkable progress in the rapidly maturing field of numerical relativity, and the new understanding of black-hole binary dynamics that is emerging. We also discuss important applications of these fundamental physics results to astrophysics, to gravitationalwave astronomy, and in other areas.

  11. Numerical modelling of fuel sprays

    Energy Technology Data Exchange (ETDEWEB)

    Bergstroem, C.

    1999-06-01

    The way the fuel is introduced into the combustion chamber is one of the most important parameters for the power output and the generation of emissions in the combustion of liquid fuels. The interaction between the turbulent gas flow field and the liquid fuel droplets, the vaporisation of them and the mixing of the gaseous fuel with the ambient air that are vital parameters in the combustion process. The use of numerical calculations is an important tool to better understand these complex interacting phenomena. This thesis reports on the numerical modelling of fuel sprays in non-reacting cases using an own developed spray module. The spray module uses the stochastic parcel method to represent the spray. The module was made in such manner that it could by coupled with different gas flow solver. Results obtained from four different gas flow solvers are presented in the thesis, including the use of two different kinds of turbulence models. In the first part the spray module is coupled with a k-{eta} based 2-D cylindrical gas flow solver. A thorough sensitivity analysis was performed on the spray and gas flow solver parameters, such as grid size dependence and sensitivity to initial values of k-{eta}. The results of the spray module were also compared to results from other spray codes, e.g. the well known KIVA code. In the second part of this thesis the spray was injected into a turbulent and fully developed crossflow studied. The spray module was attached to a LES (Large Eddy Simulation) based flow solvers enabling the study of the complex structures and time dependent phenomena involved in spray in crossflows. It was found that the spray performs an oscillatory motion and that the Strouhal number in the wake was about 0.1. Different spray breakup models were evaluated by comparing with experimental results 66 refs, 56 figs

  12. A Rapid Coliform Detector Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ORBITEC, in collaboration with Lucigen, proposes a rapid genetic detector for spaceflight water systems to enable real-time detection of E-coli with minimal...

  13. Rapid Multiplex Microbial Detector Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ORBITEC, in collaboration with Lucigen, proposes a rapid nucleic acid-based detector for spaceflight water systems to enable simultaneous quantification of multiple...

  14. SINFAC - SYSTEMS IMPROVED NUMERICAL FLUIDS ANALYSIS CODE

    Science.gov (United States)

    Costello, F. A.

    1994-01-01

    The Systems Improved Numerical Fluids Analysis Code, SINFAC, consists of additional routines added to the April 1983 revision of SINDA, a general thermal analyzer program. The purpose of the additional routines is to allow for the modeling of active heat transfer loops. The modeler can simulate the steady-state and pseudo-transient operations of 16 different heat transfer loop components including radiators, evaporators, condensers, mechanical pumps, reservoirs and many types of valves and fittings. In addition, the program contains a property analysis routine that can be used to compute the thermodynamic properties of 20 different refrigerants. SINFAC can simulate the response to transient boundary conditions. SINFAC was first developed as a method for computing the steady-state performance of two phase systems. It was then modified using CNFRWD, SINDA's explicit time-integration scheme, to accommodate transient thermal models. However, SINFAC cannot simulate pressure drops due to time-dependent fluid acceleration, transient boil-out, or transient fill-up, except in the accumulator. SINFAC also requires the user to be familiar with SINDA. The solution procedure used by SINFAC is similar to that which an engineer would use to solve a system manually. The solution to a system requires the determination of all of the outlet conditions of each component such as the flow rate, pressure, and enthalpy. To obtain these values, the user first estimates the inlet conditions to the first component of the system, then computes the outlet conditions from the data supplied by the manufacturer of the first component. The user then estimates the temperature at the outlet of the third component and computes the corresponding flow resistance of the second component. With the flow resistance of the second component, the user computes the conditions down stream, namely the inlet conditions of the third. The computations follow for the rest of the system, back to the first component

  15. Numerical prediction of shoreline adjacent to breakwater

    Digital Repository Service at National Institute of Oceanography (India)

    Mahadevan, R.; Chandramohan, P.; Nayak, B.U.

    Existing mathematical models for prediction of shoreline changes in the vicinity of a breakwater were reviewed The analytical and numerical results obtained from these models have been compared Under the numerical approach, two different implicit...

  16. Numerical calculations in quantum field theories

    Energy Technology Data Exchange (ETDEWEB)

    Rebbi, C.

    1984-01-01

    Four lecture notes are included: (1) motivation for numerical calculations in Quantum Field Theory; (2) numerical simulation methods; (3) Monte Carlo studies of Quantum Chromo Dynamics; and (4) systems with fermions. 23 references. (WHK)

  17. Central Difference Formula in Numerical Analysis.

    Science.gov (United States)

    de Alwis, Tilak

    1992-01-01

    Describes numerical differentiation and the central difference formula in numerical analysis. Presents three computer programs that approximate the first derivative of a function utilizing the central difference formula. Analyzes conditions under which the approximation formula is exact. (MDH)

  18. [Costing nuclear medicine diagnostic procedures].

    Science.gov (United States)

    Markou, Pavlos

    2005-01-01

    To the Editor: Referring to a recent special report about the cost analysis of twenty-nine nuclear medicine procedures, I would like to clarify some basic aspects for determining costs of nuclear medicine procedure with various costing methodologies. Activity Based Costing (ABC) method, is a new approach in imaging services costing that can provide the most accurate cost data, but is difficult to perform in nuclear medicine diagnostic procedures. That is because ABC requires determining and analyzing all direct and indirect costs of each procedure, according all its activities. Traditional costing methods, like those for estimating incomes and expenses per procedure or fixed and variable costs per procedure, which are widely used in break-even point analysis and the method of ratio-of-costs-to-charges per procedure may be easily performed in nuclear medicine departments, to evaluate the variability and differences between costs and reimbursement - charges.

  19. Quick Response Tracheotomy: A Novel Surgical Procedure.

    Science.gov (United States)

    Browne, Graeme A

    2016-05-01

    Quick response tracheostomy (QRT) is a novel open surgical technique to emergently establish an airway. The method is simple; the skills necessary to perform this procedure are rapidly acquired; and it is expedient, minimally traumatic, and remarkably devoid of complications often encountered with percutaneous dilatational tracheotomies, including those complications seen with cricothyroidotomies. Unlike all other tracheotomies in which considerable blunt dissection is required, QRT avoids tissue crushing because sharp dissection alone is used to acquire surgical access to the trachea. The QRT does not entail inserting a guidewire into the trachea, a standard feature for percutaneous tracheal access; it avoids any risk of unintended laceration of the posterior tracheal wall and proximal subjacent esophagus. The technique averts tracheal ring fracture and tracheoesophageal fistula complications. The QRT has a uniquely low incidence of inducing hemorrhage, and it requires no steps that cause temporary tracheal occlusion and will therefore not facilitate hypoxia. The QRT contributes minimally to conditions favorable for generating subglottic stenosis, and the procedure is swiftly executed with very low probability for external tracheal placement of the tracheostomy tube. The QRT is not a blind procedure. No special instruments are required for its execution nor is concurrent tracheoscopy required at any stage while performing a QRT as is specified for percutaneous tracheotomies. © The Author(s) 2016.

  20. Vegetation cover mapping at multiple scales using MODIS, Landsat, RapidEye, and Aircraft imageries in the Texas High Plains

    Science.gov (United States)

    Rajan, N.; Gowda, P. H.; Maas, S. J.; Basu, S.; Nair, S. S.

    2009-12-01

    Vegetation cover is an important input variable in many earth and environmental studies. In many of these studies, vegetation cover information is needed at different spatial scales. Hence, remote sensing is a popular tool to estimate vegetation cover. Numerous spectral-based models are available in the literature for mapping vegetation cover. However, very limited information is available on their ability to perform well at spatial scales different from the scale at which the model was developed. In this study, we used a procedure based on the Perpendicular Vegetation Index (PVI) to estimate vegetation cover. Using this procedure, vegetation cover is estimated from the ratio of the PVI of an image pixel to the PVI of full vegetation canopy (100% ground cover). The major advantages of this procedure compared to several other methods are that this method does not rely on empirical relationships, and can use raw remote sensing data without converting it into surface reflectance or normalization to account scene-to scene difference in vegetation. Previous studies conducted during the summer growing seasons of 2006, 2007 and 2008 in the Texas High Plains (THP) show that the method could estimate vegetation cover from Landsat imagery with an average error of less than 6%, and from high-resolution aerial images (obtained using TTAMRSS, the Texas Tech Airborne Multispectral Remote Sensing System) with an average error of less than 3%. In this study, we used this procedure to estimate vegetation cover of 10 large agricultural fields in the THP with Moderate Resolution Imaging Spectroradiometer (MODIS, 250 m resolution) and with the RapidEye (5 m resolution) imageries. The results were compared with ground-based observations and vegetation cover derived from Landsat and high resolution aircraft imageries.

  1. NASA trend analysis procedures

    Science.gov (United States)

    1993-01-01

    This publication is primarily intended for use by NASA personnel engaged in managing or implementing trend analysis programs. 'Trend analysis' refers to the observation of current activity in the context of the past in order to infer the expected level of future activity. NASA trend analysis was divided into 5 categories: problem, performance, supportability, programmatic, and reliability. Problem trend analysis uncovers multiple occurrences of historical hardware or software problems or failures in order to focus future corrective action. Performance trend analysis observes changing levels of real-time or historical flight vehicle performance parameters such as temperatures, pressures, and flow rates as compared to specification or 'safe' limits. Supportability trend analysis assesses the adequacy of the spaceflight logistics system; example indicators are repair-turn-around time and parts stockage levels. Programmatic trend analysis uses quantitative indicators to evaluate the 'health' of NASA programs of all types. Finally, reliability trend analysis attempts to evaluate the growth of system reliability based on a decreasing rate of occurrence of hardware problems over time. Procedures for conducting all five types of trend analysis are provided in this publication, prepared through the joint efforts of the NASA Trend Analysis Working Group.

  2. A numerical reference model for themomechanical subduction

    DEFF Research Database (Denmark)

    Quinquis, Matthieu; Chemia, Zurab; Tosi, Nicola

    2010-01-01

    response to systematic variations in input parameters, numerical studies often start from a 'reference' subduction model. However, the reference model often varies between different numerical studies, making it difficult to compare results directly. We aim therefore to define a numerical reference model......, and initial temperature distribution. We will show results of the evolution and dynamics of the subduction reference model using different numerical codes: a finite element code, SULEC, and two finite difference codes, YACC and FDcon....

  3. Numerical computation of aeroacoustic transfer functions for realistic airfoils

    Science.gov (United States)

    Miotto, Renato Fuzaro; Wolf, William Roberto; de Santana, Leandro Dantas

    2017-10-01

    Based on Amiet's theory formalism, we propose a numerical framework to compute the aeroacoustic transfer function of realistic airfoil geometries. The aeroacoustic transfer function relates the amplitude and phase of an incoming periodic gust to the respective unsteady lift response permitting, therefore, the application of Curle's analogy to compute the radiated noise. The methodology is focused on the airfoil leading-edge noise problem being able to also consider the trailing-edge back-scattering and, consequently, airfoil compactness effects. The approach is valid for compressible subsonic flows and the airfoil blade is assumed of large aspect ratio subjected to three-dimensional periodic gusts with supersonic velocity trace at the airfoil leading edge (i.e. supercritical gusts). This work proposes the iterative application of the boundary element method to numerically solve the boundary value problem prescribed by the linearized airfoil theory. Details of the numerical implementation are discussed and include the application of boundary conditions in different steps of the iterative procedure, treatment of derivatives in the implementation of the Kutta condition and accurate representation of singularities present at the leading- and trailing-edges. This study validates the numerical approach by comparing results with Amiet's theory obtained analytically. Subsequently, effects of realistic airfoil geometries on the leading-edge airfoil radiated noise are presented.

  4. Categorization of Musical Instrument Sounds Based on Numerical Parameters

    Science.gov (United States)

    Lewis, Rory A.; Wieczorkowska, Alicja

    In this paper we present methodology of categorization of musical instruments sounds, aiming at the continuing goal of codifying the classiffication of these sounds for automating indexing and retrieval purposes. The proposed categorization is based on numerical parameters. The motivation for this paper is based upon the fallibility of Hornbostel and Sachs generic classiffication scheme, most commonly used for categorization of musical instruments. In eliminating the discrepancies of Hornbostel and Sachs' classiffication of musical sounds we present a procedure that draws categorization from numerical attributes, describing both time domain and spectrum of sound, rather than using classiffication based directly on Hornbostel and Sachs scheme. As a result we propose a categorization system based upon the empirical musical parameters and then incorporating the resultant structure for classiffication rules.

  5. Semi-numerical evaluation of one-loop corrections

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, R.K.; Giele, W.T.; Zanderighi, G.; /Fermilab

    2005-08-01

    We present a semi-numerical algorithm to calculate one-loop virtual corrections to scattering amplitudes. The divergences of the loop amplitudes are regulated using dimensional regularization. We treat in detail the case of amplitudes with up to five external legs and massless internal lines, although the method is more generally applicable. Tensor integrals are reduced to generalized scalar integrals, which in turn are reduced to a set of known basis integrals using recursion relations. The reduction algorithm is modified near exceptional configurations to ensure numerical stability. To test the procedure we apply these techniques to one-loop corrections to the Higgs to four quark process for which analytic results have recently become available.

  6. Theoretical and applied aerodynamics and related numerical methods

    CERN Document Server

    Chattot, J J

    2015-01-01

    This book covers classical and modern aerodynamics, theories and related numerical methods, for senior and first-year graduate engineering students, including: -The classical potential (incompressible) flow theories for low speed aerodynamics of thin airfoils and high and low aspect ratio wings. - The linearized theories for compressible subsonic and supersonic aerodynamics. - The nonlinear transonic small disturbance potential flow theory, including supercritical wing sections, the extended transonic area rule with lift effect, transonic lifting line and swept or oblique wings to minimize wave drag. Unsteady flow is also briefly discussed. Numerical simulations based on relaxation mixed-finite difference methods are presented and explained. - Boundary layer theory for all Mach number regimes and viscous/inviscid interaction procedures used in practical aerodynamics calculations. There are also four chapters covering special topics, including wind turbines and propellers, airplane design, flow analogies and h...

  7. Numerical and Experimental Analyses of Residual Stresses in

    DEFF Research Database (Denmark)

    Hansen, Jan Langkjær; Hattel, Jesper; Lorentzen, Torben

    1999-01-01

    been done using the novel non-destructive technique of neutron diffraction.The thermal model takes into account the moving heat source in the V-shaped weld. The heat source is modelled by filler material being added continuously in connection with a body flux. In order to obtain a more realistic weld......Butt-welding in one pass with SMAW of two 10mm mild steel plates is investigated. In order to predict the residual stress fields associated with the welding procedure, a finite element model in 3D has been developed in ABAQUS. This model applies a sequential thermal and mechanical numerical...... analysis. In order to evaluate and refine the model parameters for the thermal analysis, the numerical results from this analysis are compared with experimental measurements of the temperature. To evaluate the predicted stress/strain fields, the mechanical model has been validated experimentally. This has...

  8. Numerical analysis of free vibrations of damped rotating structures

    Science.gov (United States)

    Gupta, K. K.

    1977-01-01

    This paper is concerned with the efficient numerical solution of damped and undamped free vibration problems of rotating structures. While structural discretization is achieved by the finite element method, the associated eigenproblem solution is effected by a combined Sturm sequence and inverse iteration technique that enables the computation of a few required roots only without having to compute any other. For structures of complex configurations, a modal synthesis technique is also presented, which is based on appropriate combinations of eigenproblem solution of various structural components. Such numerical procedures are general in nature, which fully exploit matrix sparsity inherent in finite element discretizations, and prove to be most efficient for the vibration analysis of any damped rotating structure, such as rotating machineries, helicopter and turbine blades, spinning space stations, among others.

  9. Numerical analysis of quench in coated conductors with defects

    Directory of Open Access Journals (Sweden)

    Wenbin Liu

    2016-09-01

    Full Text Available When the superconductor is subjected to local thermal perturbations, a large amount of joule heat may be generated in the conductor, which may lead to a quench. In a quench event, a normal zone irreversibly spreads throughout the conductor leading to failure of the superconducting device. In this paper, we will discuss the one-dimensional quench behavior in the coated conductors with internal defects or interface defects. Based on the numerical procedure given in the previous works, the normal zone propagation is studied by using the finite difference method. The numerical results are presented to discuss the normal zone propagation. We consider the effect of internal defect on the nonuniform temperature propagation. For the conductor with interface defects, it can be found that the normal zone propagation velocity is increased by defects.

  10. Aerodynamic design of a space vehicle using the numerical simulation technique

    OpenAIRE

    Yamamoto, Yukimitsu; Wada, Yasuhiro; Takanashi, Susumu; Ishiguro, Mitsuo; 山本 行光; 和田 安弘; 高梨 進; 石黒 満津夫

    1994-01-01

    Optimization or the aerodynamic configuration or a space vehicle 'HOPE' (H-2 Orbiting Plane) is conducted by using several numerical simulation codes in the transonic and hypersonic speed ranges. Design requirements are set on the longitudinal aerodynamic characteristics in the transonic speed and the aerodynamic heat characteristics in the hypersonic speed. This paper describes the procedure or the optimization or aerodynamic configurations by using the numerical simulation technique as an e...

  11. On some numerical characteristics of operators

    Directory of Open Access Journals (Sweden)

    M. Gürdal

    2015-01-01

    Full Text Available We investigate some numerical characteristics of Toeplitz operators including the numerical range, maximal numerical range and maximal Berezin set. Further, we establish an inequality for the Berezin number of an arbitrary operator on the Hardy–Hilbert space of the unit disc.

  12. Interagency mechanical operations group numerical systems group

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    This report consists of the minutes of the May 20-21, 1971 meeting of the Interagency Mechanical Operations Group (IMOG) Numerical Systems Group. This group looks at issues related to numerical control in the machining industry. Items discussed related to the use of CAD and CAM, EIA standards, data links, and numerical control.

  13. A parent-oriented approach to rapid toilet training

    Directory of Open Access Journals (Sweden)

    Dai Doan

    2016-12-01

    Full Text Available The current evaluation assessed the effectiveness of a rapid toilet training procedure for three young males with autism. The evaluation extended the research on rapid toilet training procedures by assessing parents’ preference to include two common toilet training components, a urine alarm and positive practice. In addition, we assessed child challenging behaviors during intervention. All parent participants’ elected not to use the urine alarm, and one parent elected to discontinue the implementation of positive practice techniques. All child participants engaged in challenging behavior with the initiation of toilet training. The toileting intervention was successful as all three participants increased successful self-initiations for the toilet and decreased accidents across home and clinic settings. All parents provided favorable social validity ratings of the treatment. Findings suggest that clinicians should partner with parents to develop individualized toileting interventions that are appropriate and effective.

  14. Determinants of procedural pain intensity in the intensive care unit. The Europain® study

    DEFF Research Database (Denmark)

    Puntillo, Kathleen A; Max, Adeline; Timsit, Jean-Francois

    2014-01-01

    in 192 ICUs in 28 countries. MEASUREMENTS AND MAIN RESULTS: Pain intensity on a 0-10 numeric rating scale increased significantly from baseline pain during all procedures (P wound drain removal, and arterial line insertion were the three most painful procedures, with median...

  15. A Bayesian Procedure for Probabilistic Tsunami Hazard Assessment

    Science.gov (United States)

    Grezio, A.; Marzocchi, W.; Sandri, L.; Gasparini, P.

    2009-04-01

    We implement a Bayesian procedure for the Probability Tsunami Hazard Assessment (PTHA). The approach is general and modular incorporating all significant information relevant for the hazard assessment, such as theoretical and empirical background, analytical or numerical models, instrumental and historical data. The procedure provides the a posteriori probability distribution that integrates the a priori probability distribution based on the physical knowledge of the process, and the likelihood based on the historical data. Also, the method deals with aleatory and epistemic uncertainties incorporating in a formal way all sources of relevant uncertainty, from the tsunami generation process to the wave propagation and impact on the coasts. The modular structure of the procedure is flexible and easy to modify and/or update as long as new models and/or information are available. Finally, the procedure is applied to an hypothetical region, Neverland, to clarify the PTHA evaluation in a realistic case.

  16. Stochastic procedures for extreme wave induced responses in flexible ships

    Directory of Open Access Journals (Sweden)

    Jørgen Juncher Jensen

    2014-12-01

    Full Text Available Different procedures for estimation of the extreme global wave hydroelastic responses in ships are discussed. Firstly, stochastic procedures for application in detailed numerical studies (CFD are outlined. The use of the First Order Reliability Method (FORM to generate critical wave episodes of short duration, less than 1 minute, with prescribed probability content is discussed for use in extreme response predictions including hydroelastic behaviour and slamming load events. The possibility of combining FORM results with Monte Carlo simulations is discussed for faster but still very accurate estimation of extreme responses. Secondly, stochastic procedures using measured time series of responses as input are considered. The Peak-over-Threshold procedure and the Weibull fitting are applied and discussed for the extreme value predictions including possible corrections for clustering effects.

  17. A numerical optimization approach to generate smoothing spherical splines

    Science.gov (United States)

    Machado, L.; Monteiro, M. Teresa T.

    2017-01-01

    Approximating data in curved spaces is a common procedure that is extremely required by modern applications arising, for instance, in aerospace and robotics industries. Here, we are particularly interested in finding smoothing cubic splines that best fit given data in the Euclidean sphere. To achieve this aim, a least squares optimization problem based on the minimization of a certain cost functional is formulated. To solve the problem a numerical algorithm is implemented using several routines from MATLAB toolboxes. The proposed algorithm is shown to be easy to implement, very accurate and precise for spherical data chosen randomly.

  18. Numerical Modelling of Electric Conductance of a thin Sheet

    Directory of Open Access Journals (Sweden)

    Mojmir Kollar

    2006-01-01

    Full Text Available In this paper the numeric modelling of total resistance of a thin sheet, with local conductivity in randomlydistributed grains higher then is that of the basic matrix, is presented. The 2D model is formed by a structure of longitudinaland transversal conductors interconnected in nodes of a square net. In all nodes, using iteration procedure, the potential isdetermined from which the conductance of sheet is computed between two touching electrodes. The described model can beused to imitate the behaviour of heterogeneous thin conducting sheets prepared by different techniques. The model wasverified in some cases where the net resistance is well known from the theory.

  19. Numerical methods for a general class of porous medium equations

    Energy Technology Data Exchange (ETDEWEB)

    Rose, M. E.

    1980-03-01

    The partial differential equation par. deltau/par. deltat + par. delta(f(u))/par. deltax = par. delta(g(u)par. deltau/par. deltax)/par. deltax, where g(u) is a non-negative diffusion coefficient that may vanish for one or more values of u, was used to model fluid flow through a porous medium. Error estimates for a numerical procedure to approximate the solution are derived. A revised version of this report will appear in Computers and Mathematics with Applications.

  20. AGREED-UPON PROCEDURES, PROCEDURES FOR AUDITING EUROPEAN GRANTS

    Directory of Open Access Journals (Sweden)

    Daniel Petru VARTEIU

    2016-12-01

    The audit of EU-funded projects is an audit based on agreed-upon procedures, which are established by the Managing Authority or the Intermediate Body. Agreed-upon procedures can be defined as engagements made in accordance with ISRS 4400, applicable to agreed-upon procedures, where the auditor undertakes to carry out the agreed-upon procedures and issue a report on factual findings. The report provided by the auditor does not express any assurance. It allows users to form their own opinions about the conformity of the expenses with the project budget as well as the eligibility of the expenses.

  1. Effect of rapid maxillary expansion on sleep characteristics in children

    OpenAIRE

    Navya Ashok; N. K. Sapna Varma; Ajith, V. V.; Siby Gopinath

    2014-01-01

    Introduction: Rapid maxillary expansion (RME) is an orthopedic treatment procedure routinely used to treat constricted maxillary arches and also a potential additional treatment in children presenting with sleep-disordered breathing (SDB). Aims and Objectives: The main objective of this study was to evaluate the effects of RME on sleep characteristics in children. Materials and Methods: Polysomnography was done on children of 8-13 years of age before expansion (T0), after expansion (T1) and a...

  2. Rapid enzymatic test for phenotypic HIV protease drug resistance

    OpenAIRE

    Hoffmann, D.; Assfalg-Machleidt, Irmgard; Nitschko, H; Helm, K. von der; Koszinowski, U.; Machleidt, Werner

    2003-01-01

    A phenotypic resistance test based on recombinant expression of the active HIV protease in E. coli from patient blood samples was developed. The protease is purified in a rapid onestep procedure as active enzyme and tested for inhibition by five selected synthetic inhibitors (amprenavir, indinavir, nelfinavir, ritonavir, and saquinavir) used presently for chemotherapy of HIVinfected patients. The HPLC system used in a previous approach was replaced by a continuous fluorogenic assay suitable f...

  3. Rapid Damage Assessment by Means of Multi-Temporal SAR — A Comprehensive Review and Outlook to Sentinel-1

    Directory of Open Access Journals (Sweden)

    Simon Plank

    2014-05-01

    Full Text Available Fast crisis response after natural disasters, such as earthquakes and tropical storms, is necessary to support, for instance, rescue, humanitarian, and reconstruction operations in the crisis area. Therefore, rapid damage mapping after a disaster is crucial, i.e., to detect the affected area, including grade and type of damage. Thereby, satellite remote sensing plays a key role due to its fast response, wide field of view, and low cost. With the increasing availability of remote sensing data, numerous methods have been developed for damage assessment. This article gives a comprehensive review of these techniques focusing on multi-temporal SAR procedures for rapid damage assessment: interferometric coherence and intensity correlation. The review is divided into six parts: First, methods based on coherence; second, the ones using intensity correlation; and third, techniques using both methodologies combined to increase the accuracy of the damage assessment are reviewed. Next, studies using additional data (e.g., GIS and optical imagery to support the damage assessment and increase its accuracy are reported. Moreover, selected studies on post-event SAR damage assessment techniques and examples of other applications of the interferometric coherence are presented. Then, the preconditions for a successful worldwide application of multi-temporal SAR methods for damage assessment and the limitations of current SAR satellite missions are reported. Finally, an outlook to the Sentinel-1 SAR mission shows possible solutions of these limitations, enabling a worldwide applicability of the presented damage assessment methods.

  4. Revised numerical wrapper for PIES code

    Science.gov (United States)

    Raburn, Daniel; Reiman, Allan; Monticello, Donald

    2015-11-01

    A revised external numerical wrapper has been developed for the Princeton Iterative Equilibrium Solver (PIES code), which is capable of calculating 3D MHD equilibria with islands. The numerical wrapper has been demonstrated to greatly improve the rate of convergence in numerous cases corresponding to equilibria in the TFTR device where magnetic islands are present. The numerical wrapper makes use of a Jacobian-free Newton-Krylov solver along with adaptive preconditioning and a sophisticated subspace-restricted Levenberg-Marquardt backtracking algorithm. The details of the numerical wrapper and several sample results are presented.

  5. Batman-cracks. Observations and numerical simulations

    Science.gov (United States)

    Selvadurai, A. P. S.; Busschen, A. Ten; Ernst, L. J.

    1991-05-01

    To ensure mechanical strength of fiber reinforced plastics (FRP), good adhesion between fibers and the matrix is considered to be an essential requirement. An efficient test of fiber-matrix interface characterization is the fragmentation test which provides information about the interface slip mechanism. This test consists of the longitudinal loading of a single fiber which is embedded in a matrix specimen. At critical loads the fiber experiences fragmentation. This fragmentation will terminate depending upon the shear-slip strength of the fiber-matrix adhesion, which is inversely proportional to average fragment lengths. Depending upon interface strength characteristics either bond or slip matrix fracture can occur at the onset of fiber fracture. Certain particular features of matrix fracture are observed at the locations of fiber fracture in situations where there is sufficient interface bond strength. These refer to the development of fractures with a complex surface topography. The experimental procedure involved in the fragmentation tests is discussed and the boundary element technique to examine the development of multiple matrix fractures at the fiber fracture locations is examined. The mechanics of matrix fracture is examined. When bond integrity is maintained, a fiber fracture results in a matrix fracture. The matrix fracture topography in a fragmentation test is complex; however, simplified conoidal fracture patterns can be used to investigate the crack extension phenomena. Via a mixed-mode fracture criterion, the generation of a conoidal fracture pattern in the matrix is investigated. The numerical results compare favorably with observed experimental data derived from tests conducted on fragmentation test specimens consisting of a single glass fiber which is embedded in a polyester matrix.

  6. Numerical modeling of facial aging.

    Science.gov (United States)

    Pitanguy, I; Pamplona, D; Weber, H I; Leta, F; Salgado, F; Radwanski, H N

    1998-07-01

    Facial aging is a biological phenomenon. Skin properties change with time, and gravity and facial expressions exert mechanical deformation. Knowledge of these alterations may suggest ways to reverse them by identifying the corresponding distortional forces. The aim of this study was to determine a pattern of change for parameters of the face during the aging process, based on the numerical fitting of measures from a sample of patients. The first aspect of this study was to define adequate facial parameters and means of measuring them. Subsequently, each parameter was defined individually, and these data were analyzed as a set. The sample for the research was restricted to a group of 40 white female patients with a history of limited exposure to the sun, with ages ranging from 25 to 65. The reason for choosing this sample was the availability of frontal pattern photographs at different ages. The parameters for each patient were measured at two different ages. A strong correlation was found between age and behavior of the parameters. This aging model can be verified qualitatively by comparing photographs of a patient with manipulated photographs simulating aging. The quantitative verification of the model was done through the comparison of the measured and the predicted parameters.

  7. Preparing Silica Aerogel Monoliths via a Rapid Supercritical Extraction Method

    Science.gov (United States)

    Gorka, Caroline A.

    2014-01-01

    A procedure for the fabrication of monolithic silica aerogels in eight hours or less via a rapid supercritical extraction process is described. The procedure requires 15-20 min of preparation time, during which a liquid precursor mixture is prepared and poured into wells of a metal mold that is placed between the platens of a hydraulic hot press, followed by several hours of processing within the hot press. The precursor solution consists of a 1.0:12.0:3.6:3.5 x 10-3 molar ratio of tetramethylorthosilicate (TMOS):methanol:water:ammonia. In each well of the mold, a porous silica sol-gel matrix forms. As the temperature of the mold and its contents is increased, the pressure within the mold rises. After the temperature/pressure conditions surpass the supercritical point for the solvent within the pores of the matrix (in this case, a methanol/water mixture), the supercritical fluid is released, and monolithic aerogel remains within the wells of the mold. With the mold used in this procedure, cylindrical monoliths of 2.2 cm diameter and 1.9 cm height are produced. Aerogels formed by this rapid method have comparable properties (low bulk and skeletal density, high surface area, mesoporous morphology) to those prepared by other methods that involve either additional reaction steps or solvent extractions (lengthier processes that generate more chemical waste).The rapid supercritical extraction method can also be applied to the fabrication of aerogels based on other precursor recipes. PMID:24637334

  8. On the numerical stability of spline function approximations to solutions of Volterra integral equations of the second kind

    CERN Document Server

    El-Tom, M E A

    1974-01-01

    A procedure, using spine functions of degree m, deficiency k-1, for obtaining approximate solutions to nonlinear Volterra integral equations of the second kind is presented. The paper is an investigation of the numerical stability of the procedure for various values of m and k. (5 refs).

  9. Lesion procedures in psychiatric neurosurgery.

    Science.gov (United States)

    Patel, Shaun R; Aronson, Joshua P; Sheth, Sameer A; Eskandar, Emad N

    2013-01-01

    Lesion procedures for psychiatric indications have a history that spans more than a century. This review provides a brief history of psychiatric surgery and addresses the most recent literature on lesion surgery for the treatment of anxiety and mood disorders. Relevant data described in publications from the early 1900 s through the modern era regarding lesion procedures for psychiatric indications, both historical and current use, are reported. The early procedures of Burkhardt, Moniz, and Freeman are reviewed, followed by descriptions of the more refined techniques of Leksell, Knight, Foltz, White, and Kelly. The application of lesion procedures to obsessive-compulsive disorder, mood disorders, and addiction are discussed. Lesioning procedures have informed modern deep brain stimulation targets. Recent lesioning studies demonstrate the efficacy and durability of these procedures in severely disabled patients. Judicious application of these techniques should continue for appropriately selected patients with severe, refractory psychiatric disorders. Copyright © 2013. Published by Elsevier Inc.

  10. Oak Ridge National Laboratory whole-body counter: internal operating procedure manual

    Energy Technology Data Exchange (ETDEWEB)

    Berger, C.D.; Lane, B.H.

    1982-08-01

    The general purpose of the ORNL Whole Body Counter is to provide a rapid estimation of the type and quantity of radionuclide deposited in the human body. This report contains a review of the equipment in use at the facility and the procedure for its operation, the standard procedure for performing a routine whole body count, and a discussion of interpretation of results.

  11. Characteristics of Mobile Payment Procedures

    OpenAIRE

    Kreyer, Nina; Pousttchi, Key; Turowski, Klaus

    2002-01-01

    Companies are not going to invest into the development of innovative applications or services unless these can be charged for appropriately. Thus, the existence of standardized and widely accepted mobile payment procedures is crucial for successful business-to-customer mobile commerce. The acceptance of mobile payment procedures depends on costs, security and convenience issues. For the latter, it is important that a procedure can be used over the different payment scenarios mobile commerce, ...

  12. Documenting Laboratory Procedures with Video.

    Science.gov (United States)

    Wyttenbach, Robert A

    2015-01-01

    Demonstrating laboratory procedures in person during class time can be time-consuming. When procedures are done under a microscope, live demonstration is also impractical because of the limited number of students who can view the demonstration at once. Creating videos beforehand, which students can watch before class and review during lab sessions, solves both of these problems. This article suggests ways to make and distribute high quality video of microscopic procedures.

  13. Colorimetry and SERS dual-mode detection of telomerase activity: combining rapid screening with high sensitivity

    Science.gov (United States)

    Zong, Shenfei; Wang, Zhuyuan; Chen, Hui; Hu, Guohua; Liu, Min; Chen, Peng; Cui, Yiping

    2014-01-01

    As an important biomarker and therapeutic target, telomerase has attracted considerable attention concerning its detection and monitoring. Here, we present a colorimetry and surface enhanced Raman scattering (SERS) dual-mode telomerase activity detection method, which has several distinctive advantages. First, colorimetric functionality allows rapid preliminary discrimination of telomerase activity by the naked eye. Second, the employment of SERS technique results in greatly improved detection sensitivity. Third, the combination of colorimetry and SERS into one detection system can ensure highly efficacious and sensitive screening of numerous samples. Besides, the avoidance of polymerase chain reaction (PCR) procedures further guarantees fine reliability and simplicity. Generally, the presented method is realized by an ``elongate and capture'' procedure. To be specific, gold nanoparticles modified with Raman molecules and telomeric repeat complementary oligonucleotide are employed as the colorimetric-SERS bifunctional reporting nanotag, while magnetic nanoparticles functionalized with telomerase substrate oligonucleotide are used as the capturing substrate. Telomerase can synthesize and elongate telomeric repeats onto the capturing substrate. The elongated telomeric repeats subsequently facilitate capturing of the reporting nanotag via hybridization between telomeric repeat and its complementary strand. The captured nanotags can cause a significant difference in the color and SERS intensity of the magnetically separated sediments. Thus both the color and SERS can be used as indicators of the telomerase activity. With fast screening ability and outstanding sensitivity, we anticipate that this method would greatly promote practical application of telomerase-based early-stage cancer diagnosis.As an important biomarker and therapeutic target, telomerase has attracted considerable attention concerning its detection and monitoring. Here, we present a colorimetry and

  14. Using a {sigma}-coordinate numerical ocean model for simulating the circulation at Ormen Lange

    Energy Technology Data Exchange (ETDEWEB)

    Eliassen, Inge K.; Berntsen, Jarle

    2000-01-01

    This report describes a numerical model for the simulation of circulation at the Ormen Lange oil field. The model uses a topography following vertical coordinate and time split integration procedure. The model is implemented for a 28 km x 46 km area at Ormen Lange. The equations are given in detail and numerical experiments are discussed. The numerical studies investigate how the flow specified at open boundaries surrounding the Ormen Lange area may be interpolated into the interior domain taking into account the conservation laws that are believed to determine the flow and the local topography.

  15. Use of Green's functions in the numerical solution of two-point boundary value problems

    Science.gov (United States)

    Gallaher, L. J.; Perlin, I. E.

    1974-01-01

    This study investigates the use of Green's functions in the numerical solution of the two-point boundary value problem. The first part deals with the role of the Green's function in solving both linear and nonlinear second order ordinary differential equations with boundary conditions and systems of such equations. The second part describes procedures for numerical construction of Green's functions and considers briefly the conditions for their existence. Finally, there is a description of some numerical experiments using nonlinear problems for which the known existence, uniqueness or convergence theorems do not apply. Examples here include some problems in finding rendezvous orbits of the restricted three body system.

  16. Fast Numerical Methods for the Design of Layered Photonic Structures with Rough Interfaces

    Science.gov (United States)

    Komarevskiy, Nikolay; Braginsky, Leonid; Shklover, Valery; Hafner, Christian; Lawson, John

    2011-01-01

    Modified boundary conditions (MBC) and a multilayer approach (MA) are proposed as fast and efficient numerical methods for the design of 1D photonic structures with rough interfaces. These methods are applicable for the structures, composed of materials with arbitrary permittivity tensor. MBC and MA are numerically validated on different types of interface roughness and permittivities of the constituent materials. The proposed methods can be combined with the 4x4 scattering matrix method as a field solver and an evolutionary strategy as an optimizer. The resulted optimization procedure is fast, accurate, numerically stable and can be used to design structures for various applications.

  17. Electronic Procedures for Medical Operations

    Science.gov (United States)

    2015-01-01

    Electronic procedures are replacing text-based documents for recording the steps in performing medical operations aboard the International Space Station. S&K Aerospace, LLC, has developed a content-based electronic system-based on the Extensible Markup Language (XML) standard-that separates text from formatting standards and tags items contained in procedures so they can be recognized by other electronic systems. For example, to change a standard format, electronic procedures are changed in a single batch process, and the entire body of procedures will have the new format. Procedures can be quickly searched to determine which are affected by software and hardware changes. Similarly, procedures are easily shared with other electronic systems. The system also enables real-time data capture and automatic bookmarking of current procedure steps. In Phase II of the project, S&K Aerospace developed a Procedure Representation Language (PRL) and tools to support the creation and maintenance of electronic procedures for medical operations. The goal is to develop these tools in such a way that new advances can be inserted easily, leading to an eventual medical decision support system.

  18. Guidelines for hazard evaluation procedures

    National Research Council Canada - National Science Library

    2008-01-01

    ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xxi 1 . Hazard Evaluation Procedures ... Management Overview ... ... Part I Preface 11 Introduction to the Guidelines 1.1 Background ... 1.2 Relationship...

  19. Pollutant Assessments Group procedures manual: Volume 2, Technical procedures

    Energy Technology Data Exchange (ETDEWEB)

    1992-03-01

    This is volume 2 of the manuals that describes the technical procedures currently in use by the Pollution Assessments Group. This manual incorporates new developments in hazardous waste assessment technology and administrative policy. Descriptions of the equipment, procedures and operations of such things as radiation detection, soil sampling, radionuclide monitoring, and equipment decontamination are included in this manual. (MB)

  20. Hybrid procedures for peripheral obstructive disease.

    Science.gov (United States)

    Schrijver, A M; Moll, F L; De Vries, J P Pm

    2010-12-01

    The incidence and prevalence of high-risk patients suffering from critical limb ischemia due to multilevel arterial obstructive disease is growing rapidly. Invasive surgical procedures to restore inflow to the crural and pedal circulation in case of TransAtlantic InterSociety Consensus C and D (TASC) lesions of the iliacofemoral arteries are related with substantial morbidity and mortality. The mid-term and long-term outcomes of sole percutaneous revascularization procedures are disappointing for TASC C and D lesions. Hybrid endovascular and open surgical revascularization procedures might be of benefit because of its less invasive character, no need for extensive venous graft material, and the ability to overcome long-segment arterial obstructions. The common femoral artery (CFA) plays a central role in most of the hybrid procedures. CFA desobstruction, in combination with open iliac angioplasty or open superficial femoral artery (SFA) angioplasty, and CFA desobstruction with remote endarterectomy of the superficial femoral artery, are commonplace. Another valuable hybrid technique is open angioplasty of the SFA and one-staged distal origin bypass grafting. Hybrid techniques can safely be performed in the vascular operating room providing that the inventory is equipped for endovascular interventions. Vascular surgeons with thorough experience in open transluminal angioplasty, whether or not in cooperation with interventional radiologists or angiologists, will have the lead in the preoperative and perioperative planning. No randomized controlled trials have been published comparing hybrid techniques and open surgical reconstructions, or sole endvascular methods for multilevel peripheral arterial disease. During the last decade, multiple prospective and retrospective series have been reported concerning hybrid techniques, all with good initial technical success (up to 95%) and acceptable 30-day morbidity and mortality rates. Mid-term and long-term patency rates are