Agricultural intensification and de-intensification differentially affect taxonomic diversity of predatory mites, earthworms, enchytraeids, nematodes and bacteria.

NARCIS (Netherlands)

Postma-Blaauw, M.B.; Goede, de R.G.M.; Bloem, J.; Faber, J.H.; Brussaard, L.

2012-01-01

Agricultural intensification is known to impact the soil biota community. In a previous study, the impact of agricultural intensification on total abundances and functional group structure of major soil biota groups were measured. In this study we address the effects of conversion of extensively

Long-term induced agricultural intensification in China

DEFF Research Database (Denmark)

Teng, Shuqing; Svenning, Jens-Christian

2016-01-01

Understanding the dynamics of agricultural intensification has great implications for biodiversity conservation faced with increasing human population and food demand. How agricultural intensification evolves with human population growth is differently described by three theories, namely......, the Boserupian, Malthusian and induced intensification theories. The Malthusian theory suggests quick adoption of available techniques that increase human population, while the other two share one viewpoint that increased intensive level of agriculture is passively induced by population growth. Which theory has...... a prediction that matches long-term dynamics of agricultural intensification in history? Using historical land-use data spanning two thousand years, this study estimated the dynamic trajectories of four cultivation practices with different intensive levels in a part of China and assessed the three theories...

Rapidity-density patterns for events in a stochastic-field multiparticle theory

International Nuclear Information System (INIS)

Arnold, R.C.

1976-02-01

Typical-event rapidity distributions expected at energies of a few TeV are calculated in a stochastic-field multiparticle production theory. Short range rapidity correlations with characteristics of a Van der Waals fluid give rise to ''domain'' patterns in rapidity density, which have the appearance of clusters separated by rapidity gaps

Fundamentals of process intensification: A process systems engineering view

DEFF Research Database (Denmark)

Babi, Deenesh Kavi; Sales Cruz, Alfonso Mauricio; Gani, Rafiqul

2016-01-01

This chapter gives an overview of the fundamentals of process intensification from a process systems engineering point of view. The concept of process intensification, including process integration, is explained together with the drivers for applying process intensification, which can be achieved...

When trends intersect: The challenge of protecting freshwater ecosystems under multiple land use and hydrological intensification scenarios.

Science.gov (United States)

Davis, Jenny; O'Grady, Anthony P; Dale, Allan; Arthington, Angela H; Gell, Peter A; Driver, Patrick D; Bond, Nick; Casanova, Michelle; Finlayson, Max; Watts, Robyn J; Capon, Samantha J; Nagelkerken, Ivan; Tingley, Reid; Fry, Brian; Page, Timothy J; Specht, Alison

2015-11-15

Intensification of the use of natural resources is a world-wide trend driven by the increasing demand for water, food, fibre, minerals and energy. These demands are the result of a rising world population, increasing wealth and greater global focus on economic growth. Land use intensification, together with climate change, is also driving intensification of the global hydrological cycle. Both processes will have major socio-economic and ecological implications for global water availability. In this paper we focus on the implications of land use intensification for the conservation and management of freshwater ecosystems using Australia as an example. We consider this in the light of intensification of the hydrologic cycle due to climate change, and associated hydrological scenarios that include the occurrence of more intense hydrological events (extreme storms, larger floods and longer droughts). We highlight the importance of managing water quality, the value of providing environmental flows within a watershed framework and the critical role that innovative science and adaptive management must play in developing proactive and robust responses to intensification. We also suggest research priorities to support improved systemic governance, including adaptation planning and management to maximise freshwater biodiversity outcomes while supporting the socio-economic objectives driving land use intensification. Further research priorities include: i) determining the relative contributions of surface water and groundwater in supporting freshwater ecosystems; ii) identifying and protecting freshwater biodiversity hotspots and refugia; iii) improving our capacity to model hydro-ecological relationships and predict ecological outcomes from land use intensification and climate change; iv) developing an understanding of long term ecosystem behaviour; and v) exploring systemic approaches to enhancing governance systems, including planning and management systems affecting

Properties of events with a rapidity gap between jets in CDF

International Nuclear Information System (INIS)

Melese, P.

1997-06-01

We present the η and E T dependence of dijet events produced by color-singlet exchange in anti pp collisions at √s = 1.8 TeV using data collected by the CDF collaboration at the Fermilab Tevatron. In a sample of events with two forward jets, where the jets are on opposite sides in rapidity with |η| > 1. 8 and E T > 20 GeV, we find 1.13 ± 0.12(stat) ± 0. 11(syst)% have a rapidity gap between the jets consistent with color- singlet exchange. This signal has no significant dependence on the jet E T or the rapidity interval between the jets

Mechanisms of the intensification of the upwelling-favorable winds during El Niño 1997-1998 in the Peruvian upwelling system

Science.gov (United States)

Chamorro, Adolfo; Echevin, Vincent; Colas, François; Oerder, Vera; Tam, Jorge; Quispe-Ccalluari, Carlos

2018-01-01

The physical processes driving the wind intensification in a coastal band of 100 km off Peru during the intense 1997-1998 El Niño (EN) event were studied using a regional atmospheric model. A simulation performed for the period 1994-2000 reproduced the coastal wind response to local sea surface temperature (SST) forcing and large scale atmospheric conditions. The model, evaluated with satellite data, represented well the intensity, seasonal and interannual variability of alongshore (i.e. NW-SE) winds. An alongshore momentum budget showed that the pressure gradient was the dominant force driving the surface wind acceleration. The pressure gradient tended to accelerate the coastal wind, while turbulent vertical mixing decelerated it. A quasi-linear relation between surface wind and pressure gradient anomalies was found. Alongshore pressure gradient anomalies were caused by a greater increase in near-surface air temperature off the northern coast than off the southern coast, associated with the inhomogeneous SST warming. Vertical profiles of wind, mixing coefficient, and momentum trends showed that the surface wind intensification was not caused by the increase of turbulence in the planetary boundary layer. Moreover, the temperature inversion in the vertical mitigated the development of pressure gradient due to air convection during part of the event. Sensitivity experiments allowed to isolate the respective impacts of the local SST forcing and large scale condition on the coastal wind intensification. It was primarily driven by the local SST forcing whereas large scale variability associated with the South Pacific Anticyclone modulated its effects. Examination of other EN events using reanalysis data confirmed that intensifications of alongshore wind off Peru were associated with SST alongshore gradient anomalies, as during the 1997-1998 event.

Intensification of ethylene glycol production process

DEFF Research Database (Denmark)

Wisutwattanaa, Apiwit; Frauzem, Rebecca; Suriyapraphadilok, Uthaiporn

2017-01-01

This study aims to generate an alternative design for ethylene glycol production process focusing on a reduction of operating cost and emissions. To achieve this, the phenomena-based method for process intensification was applied. 3 stages of process intensification were performed. First, the base......-case design was obtained, resulting in the production of ethylene glycol via two steps: ethylene oxidation synthesis followed by ethylene oxide hydration to produce ethylene glycol. Feasibility of the design was verified and the process was rigorously designed using a computer process simulation program...... solutions. As the result of intensification method, membrane separation was suggested and applied to the design. With the operation of the new equipment, the ethylene glycol production process was improved for 54.51 percent in terms of energy consumption....

Agricultural Intensification in the Brazilian Agricultural-Forest Frontier: Land Use Responses to Development and Conservation Policy

Science.gov (United States)

Garrett, R.; Koh, I.; le Polain de Waroux, Y.; Lambin, E.; Kastens, J.; Brown, J. C.

2017-12-01

Agricultural expansion, extensive cattle ranching, and deforestation remain pressing challenges for sustainable development and climate mitigation throughout South America. In response to these challenges, national and local governments, as well as private and non-governmental actors have developed new forest conservation governance mechanisms. The objective of this study is to better understand how conservation policies interact with supply chain development to influence land use. In particular, we endeavor to understand the timing and spatial patterns of crop and cattle intensification, an understudied phenomenon that is critical to understanding the future of agricultural-forest frontiers and the impacts of conservation policies. We focus on Mato Grosso, the largest soy and cattle producing state in Brazil, which spans the Cerrado and Amazon biomes and has experienced higher levels of deforestation for agricultural expansion than any other state globally over the last decade. Using a newly created spatially explicit data set of land use intensity, supply chain development, and forest policy, we find that agricultural intensification is occurring rapidly in the region, but is only partially driven by changes in conservation policies. The intensification of cattle production is the result of improvements in deforestation monitoring, penalties, and enforcement, and increased land scarcity. Crop intensification, in contrast, preceded increases in conservation restrictions, and is associated with the positive spillovers resulting from agribusiness agglomeration and development. These results suggest that intensification is not a foregone conclusion of increasing forest conservation restrictions, but is highly dependent on wider development processes. A combined effort to direct agribusiness development away from forest regions via tax credits and subsidized credit, when applied in concert with stringent conservation requirements, could help promote intensification

Bioprocess intensification for the effective production of chemical products

DEFF Research Database (Denmark)

Woodley, John

2017-01-01

The further implementation of new bioprocesses, using biocatalysts in various formats, for the synthesis of chemicals is highly dependent upon effective process intensification. The need for process intensification reflects the fact that the conditions under which a biocatalyst carries out...... a reaction in nature are far from those which are optimal for industrial processes. In this paper the rationale for intensification will be discussed, as well as the four complementary approaches used today to achieve bioprocess intensification. Two of these four approaches are based on alteration...... of the biocatalyst (either by protein engineering or metabolic engineering), resulting in an extra degree of freedom in the process design. To date, biocatalyst engineering has been developed independently from the conventional process engineering methodology to intensification. Although the integration of these two...

Closing the gap: global potential for increasing biofuel production through agricultural intensification

International Nuclear Information System (INIS)

Johnston, Matt; Foley, J; Mueller, N D; Licker, R; Holloway, T; Barford, C; Kucharik, C

2011-01-01

Since the end of World War II, global agriculture has undergone a period of rapid intensification achieved through a combination of increased applications of chemical fertilizers, pesticides, and herbicides, the implementation of best management practice techniques, mechanization, irrigation, and more recently, through the use of optimized seed varieties and genetic engineering. However, not all crops and not all regions of the world have realized the same improvements in agricultural intensity. In this study we examine both the magnitude and spatial variation of new agricultural production potential from closing of 'yield gaps' for 20 ethanol and biodiesel feedstock crops. With biofuels coming under increasing pressure to slow or eliminate indirect land-use conversion, the use of targeted intensification via established agricultural practices might offer an alternative for continued growth. We find that by closing the 50th percentile production gap-essentially improving global yields to median levels-the 20 crops in this study could provide approximately 112.5 billion liters of new ethanol and 8.5 billion liters of new biodiesel production. This study is intended to be an important new resource for scientists and policymakers alike-helping to more accurately understand spatial variation of yield and agricultural intensification potential, as well as employing these data to better utilize existing infrastructure and optimize the distribution of development and aid capital.

Closing the gap: global potential for increasing biofuel production through agricultural intensification

Science.gov (United States)

Johnston, Matt; Licker, R.; Foley, J.; Holloway, T.; Mueller, N. D.; Barford, C.; Kucharik, C.

2011-07-01

Since the end of World War II, global agriculture has undergone a period of rapid intensification achieved through a combination of increased applications of chemical fertilizers, pesticides, and herbicides, the implementation of best management practice techniques, mechanization, irrigation, and more recently, through the use of optimized seed varieties and genetic engineering. However, not all crops and not all regions of the world have realized the same improvements in agricultural intensity. In this study we examine both the magnitude and spatial variation of new agricultural production potential from closing of 'yield gaps' for 20 ethanol and biodiesel feedstock crops. With biofuels coming under increasing pressure to slow or eliminate indirect land-use conversion, the use of targeted intensification via established agricultural practices might offer an alternative for continued growth. We find that by closing the 50th percentile production gap—essentially improving global yields to median levels—the 20 crops in this study could provide approximately 112.5 billion liters of new ethanol and 8.5 billion liters of new biodiesel production. This study is intended to be an important new resource for scientists and policymakers alike—helping to more accurately understand spatial variation of yield and agricultural intensification potential, as well as employing these data to better utilize existing infrastructure and optimize the distribution of development and aid capital.

Closing the gap: global potential for increasing biofuel production through agricultural intensification

Energy Technology Data Exchange (ETDEWEB)

Johnston, Matt; Foley, J; Mueller, N D [Institute on the Environment (IonE), University of Minnesota, Saint Paul, MN 55108 (United States); Licker, R; Holloway, T; Barford, C; Kucharik, C [Center for Sustainability and the Global Environment, University of Wisconsin, Madison, WI 53726 (United States)

2011-07-15

Since the end of World War II, global agriculture has undergone a period of rapid intensification achieved through a combination of increased applications of chemical fertilizers, pesticides, and herbicides, the implementation of best management practice techniques, mechanization, irrigation, and more recently, through the use of optimized seed varieties and genetic engineering. However, not all crops and not all regions of the world have realized the same improvements in agricultural intensity. In this study we examine both the magnitude and spatial variation of new agricultural production potential from closing of 'yield gaps' for 20 ethanol and biodiesel feedstock crops. With biofuels coming under increasing pressure to slow or eliminate indirect land-use conversion, the use of targeted intensification via established agricultural practices might offer an alternative for continued growth. We find that by closing the 50th percentile production gap-essentially improving global yields to median levels-the 20 crops in this study could provide approximately 112.5 billion liters of new ethanol and 8.5 billion liters of new biodiesel production. This study is intended to be an important new resource for scientists and policymakers alike-helping to more accurately understand spatial variation of yield and agricultural intensification potential, as well as employing these data to better utilize existing infrastructure and optimize the distribution of development and aid capital.

Governance, agricultural intensification, and land sparing in tropical South America.

Science.gov (United States)

Ceddia, Michele Graziano; Bardsley, Nicholas Oliver; Gomez-y-Paloma, Sergio; Sedlacek, Sabine

2014-05-20

In this paper we address two topical questions: How do the quality of governance and agricultural intensification impact on spatial expansion of agriculture? Which aspects of governance are more likely to ensure that agricultural intensification allows sparing land for nature? Using data from the Food and Agriculture Organization, the World Bank, the World Database on Protected Areas, and the Yale Center for Environmental Law and Policy, we estimate a panel data model for six South American countries and quantify the effects of major determinants of agricultural land expansion, including various dimensions of governance, over the period 1970-2006. The results indicate that the effect of agricultural intensification on agricultural expansion is conditional on the quality and type of governance. When considering conventional aspects of governance, agricultural intensification leads to an expansion of agricultural area when governance scores are high. When looking specifically at environmental aspects of governance, intensification leads to a spatial contraction of agriculture when governance scores are high, signaling a sustainable intensification process.

Hypertension treatment intensification among stroke survivors with uncontrolled blood pressure.

Science.gov (United States)

Roumie, Christianne L; Zillich, Alan J; Bravata, Dawn M; Jaynes, Heather A; Myers, Laura J; Yoder, Joseph; Cheng, Eric M

2015-02-01

We examined blood pressure 1 year after stroke discharge and its association with treatment intensification. We examined the systolic blood pressure (SBP) stratified by discharge SBP (≤140, 141-160, or >160 mm Hg) among a national cohort of Veterans discharged after acute ischemic stroke. Hypertension treatment opportunities were defined as outpatient SBP >160 mm Hg or repeated SBPs >140 mm Hg. Treatment intensification was defined as the proportion of treatment opportunities with antihypertensive changes (range, 0%-100%, where 100% indicates that each elevated SBP always resulted in medication change). Among 3153 patients with ischemic stroke, 38% had ≥1 elevated outpatient SBP eligible for treatment intensification in the 1 year after stroke. Thirty percent of patients had a discharge SBP ≤140 mm Hg, and an average 1.93 treatment opportunities and treatment intensification occurred in 58% of eligible visits. Forty-seven percent of patients discharged with SBP 141 to160 mm Hg had an average of 2.1 opportunities for intensification and treatment intensification occurred in 60% of visits. Sixty-three percent of the patients discharged with an SBP >160 mm Hg had an average of 2.4 intensification opportunities, and treatment intensification occurred in 65% of visits. Patients with discharge SBP >160 mm Hg had numerous opportunities to improve hypertension control. Secondary stroke prevention efforts should focus on initiation and review of antihypertensives before acute stroke discharge; management of antihypertensives and titration; and patient medication adherence counseling. © 2014 American Heart Association, Inc.

Governance, agricultural intensification, and land sparing in tropical South America

Science.gov (United States)

Ceddia, Michele Graziano; Bardsley, Nicholas Oliver; Gomez-y-Paloma, Sergio; Sedlacek, Sabine

2014-01-01

In this paper we address two topical questions: How do the quality of governance and agricultural intensification impact on spatial expansion of agriculture? Which aspects of governance are more likely to ensure that agricultural intensification allows sparing land for nature? Using data from the Food and Agriculture Organization, the World Bank, the World Database on Protected Areas, and the Yale Center for Environmental Law and Policy, we estimate a panel data model for six South American countries and quantify the effects of major determinants of agricultural land expansion, including various dimensions of governance, over the period 1970–2006. The results indicate that the effect of agricultural intensification on agricultural expansion is conditional on the quality and type of governance. When considering conventional aspects of governance, agricultural intensification leads to an expansion of agricultural area when governance scores are high. When looking specifically at environmental aspects of governance, intensification leads to a spatial contraction of agriculture when governance scores are high, signaling a sustainable intensification process. PMID:24799696

A study of rapidity gaps in e+e- → Z0 events

International Nuclear Information System (INIS)

1995-07-01

Distributions of rapidity gaps between charged particles are studied in Z 0 decay events recorded by the SLD experiment at SLAC. We find that our measured gap spectra are well modeled by standard Monte Carlo simulations of hadronisation. Gaps in hadronic events are studied as a function of event primary flavor, jet multiplicity and total charged multiplicity

Novel process intensification techniques in solvent extraction. Contributed Paper IT-09

International Nuclear Information System (INIS)

Ghosh, S.K.

2014-01-01

Process intensification can be briefly described as any chemical engineering development that leads to substantially smaller, cleaner and more energy efficient technology. Process intensification in active nuclear material processing will offer additional benefit in terms of reduced containment volume. The intensification can be realized either by use of novel equipment or by novel operating techniques. Feasibility of hollow fiber (HF) modules and microchannels or microfluidic devices will be explained for their utilization in process intensification of solvent extraction operation in nuclear fuel cycle

Rotational diversification and intensification

Science.gov (United States)

Diversification and intensification of inland Pacific Northwest (PNW) dryland cereal cropping systems can present win-win scenarios that deliver short and long-term benefits for producers and the environment, stabilizing profit and increasing adaptability to and mitigation of climate change. Improvi...

Heat and mass transfer intensification and shape optimization a multi-scale approach

CERN Document Server

2013-01-01

Is the heat and mass transfer intensification defined as a new paradigm of process engineering, or is it just a common and old idea, renamed and given the current taste? Where might intensification occur? How to achieve intensification? How the shape optimization of thermal and fluidic devices leads to intensified heat and mass transfers? To answer these questions, Heat & Mass Transfer Intensification and Shape Optimization: A Multi-scale Approach clarifies  the definition of the intensification by highlighting the potential role of the multi-scale structures, the specific interfacial area, the distribution of driving force, the modes of energy supply and the temporal aspects of processes.   A reflection on the methods of process intensification or heat and mass transfer enhancement in multi-scale structures is provided, including porous media, heat exchangers, fluid distributors, mixers and reactors. A multi-scale approach to achieve intensification and shape optimization is developed and clearly expla...

Determinants Of Dairy Intensification In Uganda - An Integrated ...

African Journals Online (AJOL)

It is worthwhile to suspect that farmers are exposed to variable human capital, market access, land and labour resources, agro-climatic and location factors that influence the level of intensification adopted. The purpose of this study was to assess the factors that determine adoption of dairy intensification. Data used in the ...

Frequency, predictors, and consequences of maintenance infliximab therapy intensification in ulcerative colitis

Directory of Open Access Journals (Sweden)

Luis Fernández-Salazar

2015-09-01

Full Text Available Introduction: Infliximab (IFX therapy intensification in ulcerative colitis (UC is more common than established in pivotal studies. Objectives: To establish the frequency and form of intensification for UC in clinical practice, as well as predictors, and to compare outcomes between intensified and non-intensified treatment. Methods: A retrospective study of 10 hospitals and 144 patients with response to infliximab (IFX induction. Predictive variables for intensification were analyzed using a Cox regression analysis. Outcome, loss of response to IFX, and colectomy were compared between intensified and non-intensified therapy. Results: Follow-up time from induction to data collection: 38 months [interquartile range (IQR, 20-62]. Time on IFX therapy: 24 months (IQR, 10-44. In all, 37% of patients required intensification. Interval was shortened for 36 patients, dose was increased for 7, and 10 subjects received both. Concurrent thiopurine immunosuppressants (IMM and IFX initiation was an independent predictor of intensification [Hazard ratio, 0.034; p, 0.006; CI, 0.003-0.371]. In patients on intensified therapy IFX discontinuation for loss of response (30.4% vs. 10.2%; p, 0.002, steroid reintroduction (35% vs. 18%; p, 0.018, and colectomy (22% vs. 6.4%; p, 0.011 were more common. Of patients on intensification, 17% returned to receiving 5 mg/kg every 8 weeks. Conclusions: Intensification is common and occasionally reversible. IMM initiation at the time of induction with IFX predicts non-intensification. Intensification, while effective, is associated with poorer outcome.

Older drivers and rapid deceleration events: Salisbury Eye Evaluation Driving Study.

Science.gov (United States)

Keay, Lisa; Munoz, Beatriz; Duncan, Donald D; Hahn, Daniel; Baldwin, Kevin; Turano, Kathleen A; Munro, Cynthia A; Bandeen-Roche, Karen; West, Sheila K

2013-09-01

Drivers who rapidly change speed while driving may be more at risk for a crash. We sought to determine the relationship of demographic, vision, and cognitive variables with episodes of rapid decelerations during five days of normal driving in a cohort of older drivers. In the Salisbury Eye Evaluation Driving Study, 1425 older drivers aged 67-87 were recruited from the Maryland Motor Vehicle Administration's rolls for licensees in Salisbury, Maryland. Participants had several measures of vision tested: visual acuity, contrast sensitivity, visual fields, and the attentional visual field. Participants were also tested for various domains of cognitive function including executive function, attention, psychomotor speed, and visual search. A custom created driving monitoring system (DMS) was used to capture rapid deceleration events (RDEs), defined as at least 350 milli-g deceleration, during a five day period of monitoring. The rate of RDE per mile driven was modeled using a negative binomial regression model with an offset of the logarithm of the number of miles driven. We found that 30% of older drivers had one or more RDE during a five day period, and of those, about 1/3 had four or more. The rate of RDE per mile driven was highest for those drivers drivingRDE's were more likely to have better scores in cognitive tests of psychomotor speed and visual search, and have faster brake reaction time. Further, greater average speed and maximum speed per driving segment was protective against RDE events. In conclusion, contrary to our hypothesis, older drivers who perform rapid decelerations tend to be more "fit", with better measures of vision and cognition compared to those who do not have events of rapid deceleration. Copyright © 2012 Elsevier Ltd. All rights reserved.

Increasing magnitude of Hurricane Rapid Intensification in the central-eastern Atlantic over the past 30 years

Science.gov (United States)

Leung, L. R.; Balaguru, K.; Foltz, G. R.

2017-12-01

During the 2017 Atlantic hurricane season, several hurricanes underwent rapid intensification (RI) in the central-eastern Atlantic. This motivates an analysis of trends in the strength of hurricane RI during the 30-year post-satellite period of 1986-2015. Our results show that in the eastern tropical Atlantic, to the east of 60W, the mean RI magnitude averaged during 2001-2015 was 3.8 kt per 24 hr higher than during 1986-2000. However, in the western tropical Atlantic, to the west of 60W, changes in RI magnitude over the same period were not statistically significant. We examined the large-scale environment to understand the causes behind these changes in RI magnitude and found that various oceanic and atmospheric parameters that play an important role in RI changed favorably in the eastern tropical Atlantic. More specifically, changes in SST, Potential Intensity, upper-ocean heat content, wind shear, relative humidity and upper-level divergence enhanced the ability for hurricanes to undergo RI in the eastern tropical Atlantic. In contrast, changes in the same factors are inconsistent in the western tropical Atlantic. While changes in SST and Potential Intensity were positive, changes in upper-ocean heat content, wind shear and upper-level divergence were either insignificant or unfavorable for RI. Finally, we examined the potential role of various climate phenomena, which are well-known to impact Atlantic hurricane activity, in causing the changes in the large-scale environment. Our analysis reveals that changes in the Atlantic Multidecadal Oscillation over the 30-year period are predominantly responsible. These results provide important aspects of the large-scale context to understand the Atlantic hurricane season of 2017.

Comparison of energy flows in deep inelastic scattering events with and without a large rapidity gap

International Nuclear Information System (INIS)

Derrick, M.; Krakauer, D.; Magill, S.

1994-07-01

Energy flows in deep inelastic electron-proton scattering are investigated at a centre-of-mass energy of 296 GeV for the range Q 2 ≥10 GeV 2 using the ZEUS detector. A comparison is made between events with and without a large rapidity gap between the hadronic system and the proton direction. The energy flows, corrected for detector acceptance and resolution, are shown for these two classes of events in both the HERA laboratory frame and the Breit frame. From the differences in the shapes of these energy flows we conclude that QCD radiation is suppressed in the large-rapidity-gap events compared to the events without a large rapidity gap. (orig.)

Characterizing the Frequency and Elevation of Rapid Drainage Events in West Greenland

Science.gov (United States)

Cooley, S.; Christoffersen, P.

2016-12-01

Rapid drainage of supraglacial lakes on the Greenland Ice Sheet is critical for the establishment of surface-to-bed hydrologic connections and the subsequent transfer of water from surface to bed. Yet, estimates of the number and spatial distribution of rapidly draining lakes vary widely due to limitations in the temporal frequency of image collection and obscureness by cloud. So far, no study has assessed the impact of these observation biases. In this study, we examine the frequency and elevation of rapidly draining lakes in central West Greenland, from 68°N to 72.6°N, and we make a robust statistical analysis to estimate more accurately the likelihood of lakes draining rapidly. Using MODIS imagery and a fully automated lake detection method, we map more than 500 supraglacial lakes per year over a 63000 km2 study area from 2000-2015. Through testing four different definitions of rapidly draining lakes from previously published studies, we find that the number of rapidly draining lakes varies from 3% to 38%. Logistic regression between rapid drainage events and image sampling frequency demonstrates that the number of rapid drainage events is strongly dependent on cloud-free observation percentage. We then develop three new drainage criteria and apply an observation bias correction that suggests a true rapid drainage probability between 36% and 45%, considerably higher than previous studies without bias assessment have reported. We find rapid-draining lakes are on average larger and disappear earlier than slow-draining lakes, and we also observe no elevation differences for the lakes detected as rapidly draining. We conclude a) that methodological problems in rapid drainage research caused by observation bias and varying detection methods have obscured large-scale rapid drainage characteristics and b) that the lack of evidence for an elevation limit on rapid drainage suggests surface-to-bed hydrologic connections may continue to propagate inland as climate warms.

Sustainable intensification of agriculture for human prosperity and global sustainability

NARCIS (Netherlands)

Rockstrom, J.; Williams, J.; Daily, G.; Noble, A.; Matthews, N.; Gordon, L.; Wetterstrand, H.; DeClerck, F.; Fraiture, de C.M.S.

2017-01-01

There is an ongoing debate on what constitutes sustainable intensification of agriculture (SIA). In this paper, we propose that a paradigm for sustainable intensification can be defined and translated into an operational framework for agricultural development. We argue that this paradigm must now be

Assessment of work intensification by managers and psychological distressed and non-distressed employees: a multilevel comparison.

Science.gov (United States)

Bamberger, Simon Grandjean; Larsen, Anelia; Vinding, Anker Lund; Nielsen, Peter; Fonager, Kirsten; Nielsen, René Nesgaard; Ryom, Pia; Omland, Øyvind

2015-01-01

Work intensification is a popular management strategy to increase productivity, but at the possible expense of employee mental stress. This study examines associations between ratings of work intensification and psychological distress, and the level of agreement between compared employee-rated and manager-rated work intensification. Multi-source survey data were collected from 3,064 employees and 573 company managers from the private sector in 2010. Multilevel regression models were used to compare different work intensification ratings across psychological distress strata. Distressed employees rated higher degree of total work intensification compared to non-distressed employees, and on three out of five sub ratings there were an increased prevalence of work intensification in the case group. In general, there was poor agreement between employee and company work intensification rating. Neither manager-rated work intensification nor employee/manager discrepancy in work intensification ratings was associated with psychological distress. Distressed employees had a higher total score of employee/manager agreed work intensification, and a higher prevalence of increased demands of labour productivity. This study demonstrates higher ratings of employee/manager agreed work intensification in distressed employees compared to non-distressed employees, challenging previous findings of reporting bias in distressed employees' assessment of work environment.

The role of process intensification in cutting greenhouse gas emissions

International Nuclear Information System (INIS)

Reay, David

2008-01-01

Between 1900 and 1955 the average rate of global energy use rose from about 1 TW to 2 TW. Between 1955 and 1999 energy use rose from 2 TW to about 12 TW, and to 2006 a further 16% growth in primary energy use was recorded world-wide. There are recommendations by the UK Royal Commission on Environmental Pollution, subsequently supported by others in the UK, that we need to reduce CO 2 emissions by over 50% in order to stabilise their impact on global warming (CO 2 being the principal gas believed to be contributing to this phenomenon). One way in which we can address this is by judicious use of process intensification technology. Process intensification may be defined as: 'Any engineering development that leads to a substantially smaller, cleaner, safer and more energy-efficient technology.' It is most often characterised by a huge reduction in plant volume - orders of magnitude - but its contribution to reducing greenhouse gas emissions may also be significant. Potential energy savings due to investment in process intensification were studied by several UK organisations in the mid 1990s, to assist the UK Government in formulating a strategy on intensification. It is relevant to the themes of the PRES 07 Conference that process integration features in these analyses. Overall plant intensification in the UK was identified as having a technical potential of 40 PJ/year (about 1 million tonnes of oil equivalent/annum). The total potential energy savings due to investment in process intensification in a range of process unit operations were predicted to be over 74 PJ/year (1 PJ = 10 15 J). Projections for The Netherlands suggest that savings of 50-100 PJ/year should be achieved across chemicals and food processing by 2050. Substantial benefits to industry in the USA are highlighted by US Department of Energy studies. This paper relates by discussion and example process intensification to the main themes of the PRES 07 Conference, including process integration. It also

The Effect of Lead Intensification Screens on Film: Modeling and Experiment

International Nuclear Information System (INIS)

Wendt, S.; Gray, J.; Zhou, C.

2004-01-01

A physics-based, intensification screen model, using lead as an example, has been developed. Comparisons to experimental results are shown. The dominant effect in producing the intensification is from photoelectrons ejected from a 24 - 40 micron layer of lead near the film with Compton electrons and the lead fluorescence x-rays contributing less than 10% to the intensification for settings below 300 kvp. The thickness of lead screen for optimal intensification is between 15 and 70 microns depending upon the energy of the photon. This is less than the traditional practice of a 130 microns front screen and 260 microns back screen. The model computes the intensifying effect of lead screens placed in front or in back of a sheet of radiographic film and accounts for the strong energy dependent effects contributing to the intensification. The lead screen model is independent of film type, so the user can select any type of film and any combination of lead thickness for the front and back screens. The model uses energy dependent x-ray photon absorption cross-sections to compute the production of electrons in the lead. A Monte Carlo calculation was used to determine energy dependent electron penetration in the lead and the film. The model calculates electron attenuation in the film emulsion, the film substrate and both front and back lead screens and determines the intensification effect as a function of the energy deposited in the film. For model validation, lead screen intensification was studied with x-ray generator settings ranging from 75 to 320 kvp and using various thicknesses of aluminum and iron attenuators to filter the x-ray beam. A high precision motion control system coupled with a high purity germanium detector was used to study the energy spectra

Agricultural intensification : saving space for wildlife?

NARCIS (Netherlands)

Baudron, F.

2011-01-01

Key words: agricultural frontier; smallholder; intensification; semi-arid area; wildlife; conservation agriculture; cotton; Zimbabwe.

Increasing agricultural production and preventing further losses in biodiversity are both legitimate objectives, but they compete strongly in the

Photoproduction of events with rapidity gaps between jets at HERA

Energy Technology Data Exchange (ETDEWEB)

Chekanov, S.; Derrick, M.; Magill, S. [Argonne National Laboratory, Argonne, IL (US)] (and others)

2006-12-15

The photoproduction of dijet events, where the two jets with the highest transverse energy are separated by a large gap in pseudorapidity, have been studied with the ZEUS detector using an integrated luminosity of 39 pb{sup -1}. Rapidity-gap events are defined in terms of the energy flow between the jets, such that the total summed transverse energy in this region is less than some value E{sub T}{sup C}UT. The data show a clear excess over the predictions of standard photoproduction models. This is interpreted as evidence for a strongly interacting exchange of a color-singlet object. Monte Carlo models which include such a color-singlet exchange are able to describe the data. (orig.)

Photoproduction of events with rapidity gaps between jets at HERA

International Nuclear Information System (INIS)

Chekanov, S.; Derrick, M.; Magill, S.

2006-12-01

The photoproduction of dijet events, where the two jets with the highest transverse energy are separated by a large gap in pseudorapidity, have been studied with the ZEUS detector using an integrated luminosity of 39 pb -1 . Rapidity-gap events are defined in terms of the energy flow between the jets, such that the total summed transverse energy in this region is less than some value E T C UT. The data show a clear excess over the predictions of standard photoproduction models. This is interpreted as evidence for a strongly interacting exchange of a color-singlet object. Monte Carlo models which include such a color-singlet exchange are able to describe the data. (orig.)

Future Simulated Intensification of Precipitation Extremes, CMIP5 Model Uncertainties and Dependencies

Science.gov (United States)

Bador, M.; Donat, M.; Geoffroy, O.; Alexander, L. V.

2017-12-01

Precipitation intensity during extreme events is expected to increase with climate change. Throughout the 21st century, CMIP5 climate models project a general increase in annual extreme precipitation in most regions. We investigate how robust this future increase is across different models, regions and seasons. We find that there is strong similarity in extreme precipitation changes between models that share atmospheric physics, reducing the ensemble of 27 models to 14 independent projections. We find that future simulated extreme precipitation increases in most models in the majority of land grid cells located in the dry, intermediate and wet regions according to each model's precipitation climatology. These increases significantly exceed the range of natural variability estimated from long equilibrium control runs. The intensification of extreme precipitation across the entire spectrum of dry to wet regions is particularly robust in the extra-tropics in both wet and dry season, whereas uncertainties are larger in the tropics. The CMIP5 ensemble therefore indicates robust future intensification of annual extreme rainfall in particular in extra-tropical regions. Generally, the CMIP5 robustness is higher during the dry season compared to the wet season and the annual scale, but inter-model uncertainties in the tropics remain important.

Rapid formation of a modern bedrock canyon by a single flood event

Science.gov (United States)

Lamb, Michael P.; Fonstad, Mark A.

2010-07-01

Deep river canyons are thought to form slowly over geological time (see, for example, ref. 1), cut by moderate flows that reoccur every few years. In contrast, some of the most spectacular canyons on Earth and Mars were probably carved rapidly during ancient megaflood events. Quantification of the flood discharge, duration and erosion mechanics that operated during such events is hampered because we lack modern analogues. Canyon Lake Gorge, Texas, was carved in 2002 during a single catastrophic flood. The event offers a rare opportunity to analyse canyon formation and test palaeo-hydraulic-reconstruction techniques under known topographic and hydraulic conditions. Here we use digital topographic models and visible/near-infrared aerial images from before and after the flood, discharge measured during the event, field measurements and sediment-transport modelling to show that the flood moved metre-sized boulders, excavated ~7m of limestone and transformed a soil-mantled valley into a bedrock canyon in just ~3days. We find that canyon morphology is strongly dependent on rock type: plucking of limestone blocks produced waterfalls, inner channels and bedrock strath terraces, whereas abrasion of cemented alluvium sculpted walls, plunge pools and streamlined islands. Canyon formation was so rapid that erosion might have been limited by the ability of the flow to transport sediment. We suggest that our results might improve hydraulic reconstructions of similar megafloods on Earth and Mars.

Radiation Therapy Intensification for Solid Tumors: A Systematic Review of Randomized Trials

Energy Technology Data Exchange (ETDEWEB)

Yamoah, Kosj [Department of Radiation Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL (United States); Showalter, Timothy N. [Department of Radiation Oncology, University of Virginia School of Medicine, Charlottesville, Virginia (United States); Ohri, Nitin, E-mail: ohri.nitin@gmail.com [Department of Radiation Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York (United States)

2015-11-15

Purpose: To systematically review the outcomes of randomized trials testing radiation therapy (RT) intensification, including both dose escalation and/or the use of altered fractionation, as a strategy to improve disease control for a number of malignancies. Methods and Materials: We performed a literature search to identify randomized trials testing RT intensification for cancers of the central nervous system, head and neck, breast, lung, esophagus, rectum, and prostate. Findings were described qualitatively. Where adequate data were available, pooled estimates for the effect of RT intensification on local control (LC) or overall survival (OS) were obtained using the inverse variance method. Results: In primary central nervous system tumors, esophageal cancer, and rectal cancer, randomized trials have not demonstrated that RT intensification improves clinical outcomes. In breast cancer and prostate cancer, dose escalation has been shown to improve LC or biochemical disease control but not OS. Radiation therapy intensification may improve LC and OS in head and neck and lung cancers, but these benefits have generally been limited to studies that did not incorporate concurrent chemotherapy. Conclusions: In randomized trials, the benefits of RT intensification have largely been restricted to trials in which concurrent chemotherapy was not used. Novel strategies to optimize the incorporation of RT in the multimodality treatment of solid tumors should be explored.

Adoption et intensification du Nouveau Riz pour l'Afrique en Centrafrique

Directory of Open Access Journals (Sweden)

Mbétid-Bessane, E.

2014-01-01

Full Text Available Adoption and Intensification of New Rice for Africa in the Central African Republic. The objective of the study is to highlight the determinants of adoption and intensification of Nerica (new rice for Africa varieties in order to propose actions to increase sustainably rice production. To achieve this goal, the working method is based on surveys conducted with two passes with 150 rice farmers in the suburban area of Bangui where two varieties of Nerica (irrigated NL60 and rainfed N7 were disseminated. Descriptive analysis and econometric tools have been used for processing the data collected. The results show that the rate of adoption of the Nerica varieties is 33% after two years of introduction and it is determined by social and institutional variables. The level of intensification by improved seeds and chemical fertilizers is however still low and is determined, beside the institutional and social variables, by economic variables. The most decisive variables of rice intensification are agricultural income and access to credit. Thus, actions to implement should focus firstly on the level of intensification of those who have already adopted the inputs, and secondly on improving adoption rates of the different inputs. These actions will involve (i the capacity building of rice producers by literacy, agricultural training and extension, and (ii improving the business environment through access to credit and a better marketing organization.

On Quality Intensification Expression Means in German And Lithuanian

Directory of Open Access Journals (Sweden)

Ernesta Račienė

2013-12-01

Full Text Available The paper presents the analysis of German Adjectives’ derivational means, which intensify the meaning of quality, and which are compared with functional equivalents in Lithuanian. The intensification of quality is treated as the functional semantic category, implemented in various language levels. This semantics may be expressed morphologically, by lexical and syntactic means, as well as by stress and intonation. The German language has many first components of compound adjectives, representing the intensification of quality, such as: stock-, blitz-, hoch-, brand-, grund-, etc. The rendering function of this semantics is typical of German adjectives prefixes erz-, ur- as well as prefixes of foreign origin super-, ultra-, extra-, mega-, hyper-, top-. In the Lithuanian language, the intensifying meaning of quality is realized by syntactic com-pounds, while on the morphological level it can be conveyed by diminutive suffixes. The paper presents the comparison of German and Lithuanian quality intensification expression means in order to highlight typological similarities and differences.

Urban Intensification and Expansion in Sub-Saharan Africa: Impacts on Urban Agriculture and Food Security

Science.gov (United States)

Uzokwe, V. N. E. N.; Muchelo, R. O.; Odeh, I. A.

2015-12-01

In Sub-Saharan Africa (SSA), urban intensification and expansion are increasing at alarming rates due to rapid population growth and rural-to-urban migration. This has led to the premise that the proportion of SSA urban residents most vulnerable to food insecurity is the highest in the world. Using a focused survey and multi-temporal (decadal) land use/cover classification of Landsat images, we explored the effect of urban intensification and expansion on urban agriculture and food security, focusing on a megacity and a regional center in Uganda: Kampala and Mbarara, respectively. We found that food insecurity arose due to a number of reasons, among which are: i) expansion and intensification of of urban settlements into previously productive agricultural lands in urban and peri-urban areas; ii) loss of predominantly young (rural agricultural) adult labor force to urban centers, leading to decline in rural food production; iii) lack of proper urban planning incorporating green and agricultural development leading to low productive market garden systems. We discussed these outcomes in light of existing studies which estimated that urban agriculture alone supports over 800 million people globally and accounts for 15-20% of world food supply. In spite of this relatively low contribution by urban/peri-urban agriculture, it probably accounts for higher proportion of food supply to urban poor in SSA and thus are most vulnerable to the loss of urban and peri-urban agricultural land. Further recommendations require policy makers and urban planners to team up to design a suitable framework for sustainable urban planning and development.

Diversification and intensification of agricultural adaptation from global to local scales.

Directory of Open Access Journals (Sweden)

Minjie Chen

Full Text Available Smallholder farming systems are vulnerable to a number of challenges, including continued population growth, urbanization, income disparities, land degradation, decreasing farm size and productivity, all of which are compounded by uncertainty of climatic patterns. Understanding determinants of smallholder farming practices is critical for designing and implementing successful interventions, including climate change adaptation programs. We examine two dimensions wherein smallholder farmers may adapt agricultural practices; through intensification (i.e., adopt more practices or diversification (i.e. adopt different practices. We use data on 5314 randomly sampled households located in 38 sites in 15 countries across four regions (East and West Africa, South Asia, and Central America. We estimate empirical models designed to assess determinants of both intensification and diversification of adaptation activities at global scales. Aspects of adaptive capacity that are found to increase intensification of adaptation globally include variables associated with access to information and human capital, financial considerations, assets, household infrastructure and experience. In contrast, there are few global drivers of adaptive diversification, with a notable exception being access to weather information, which also increases adaptive intensification. Investigating reasons for adaptation indicate that conditions present in underdeveloped markets provide the primary impetus for adaptation, even in the context of climate change. We also compare determinants across spatial scales, which reveals a variety of local avenues through which policy interventions can relax economic constraints and boost agricultural adaptation for both intensification and diversification. For example, access to weather information does not affect intensification adaptation in Africa, but is significant at several sites in Bangladesh and India. Moreover, this information leads to

Diversification and intensification of agricultural adaptation from global to local scales

Science.gov (United States)

Chen, Minjie; Wichmann, Bruno; Luckert, Marty; Winowiecki, Leigh; Förch, Wiebke

2018-01-01

Smallholder farming systems are vulnerable to a number of challenges, including continued population growth, urbanization, income disparities, land degradation, decreasing farm size and productivity, all of which are compounded by uncertainty of climatic patterns. Understanding determinants of smallholder farming practices is critical for designing and implementing successful interventions, including climate change adaptation programs. We examine two dimensions wherein smallholder farmers may adapt agricultural practices; through intensification (i.e., adopt more practices) or diversification (i.e. adopt different practices). We use data on 5314 randomly sampled households located in 38 sites in 15 countries across four regions (East and West Africa, South Asia, and Central America). We estimate empirical models designed to assess determinants of both intensification and diversification of adaptation activities at global scales. Aspects of adaptive capacity that are found to increase intensification of adaptation globally include variables associated with access to information and human capital, financial considerations, assets, household infrastructure and experience. In contrast, there are few global drivers of adaptive diversification, with a notable exception being access to weather information, which also increases adaptive intensification. Investigating reasons for adaptation indicate that conditions present in underdeveloped markets provide the primary impetus for adaptation, even in the context of climate change. We also compare determinants across spatial scales, which reveals a variety of local avenues through which policy interventions can relax economic constraints and boost agricultural adaptation for both intensification and diversification. For example, access to weather information does not affect intensification adaptation in Africa, but is significant at several sites in Bangladesh and India. Moreover, this information leads to diversification of

Ocean barrier layers' effect on tropical cyclone intensification.

Science.gov (United States)

Balaguru, Karthik; Chang, Ping; Saravanan, R; Leung, L Ruby; Xu, Zhao; Li, Mingkui; Hsieh, Jen-Shan

2012-09-04

Improving a tropical cyclone's forecast and mitigating its destructive potential requires knowledge of various environmental factors that influence the cyclone's path and intensity. Herein, using a combination of observations and model simulations, we systematically demonstrate that tropical cyclone intensification is significantly affected by salinity-induced barrier layers, which are "quasi-permanent" features in the upper tropical oceans. When tropical cyclones pass over regions with barrier layers, the increased stratification and stability within the layer reduce storm-induced vertical mixing and sea surface temperature cooling. This causes an increase in enthalpy flux from the ocean to the atmosphere and, consequently, an intensification of tropical cyclones. On average, the tropical cyclone intensification rate is nearly 50% higher over regions with barrier layers, compared to regions without. Our finding, which underscores the importance of observing not only the upper-ocean thermal structure but also the salinity structure in deep tropical barrier layer regions, may be a key to more skillful predictions of tropical cyclone intensities through improved ocean state estimates and simulations of barrier layer processes. As the hydrological cycle responds to global warming, any associated changes in the barrier layer distribution must be considered in projecting future tropical cyclone activity.

Using Rapid Improvement Events for Disaster After-Action Reviews: Experience in a Hospital Information Technology Outage and Response.

Science.gov (United States)

Little, Charles M; McStay, Christopher; Oeth, Justin; Koehler, April; Bookman, Kelly

2018-02-01

The use of after-action reviews (AARs) following major emergency events, such as a disaster, is common and mandated for hospitals and similar organizations. There is a recurrent challenge of identified problems not being resolved and repeated in subsequent events. A process improvement technique called a rapid improvement event (RIE) was used to conduct an AAR following a complete information technology (IT) outage at a large urban hospital. Using RIE methodology to conduct the AAR allowed for the rapid development and implementation of major process improvements to prepare for future IT downtime events. Thus, process improvement methodology, particularly the RIE, is suited for conducting AARs following disasters and holds promise for improving outcomes in emergency management. Little CM , McStay C , Oeth J , Koehler A , Bookman K . Using rapid improvement events for disaster after-action reviews: experience in a hospital information technology outage and response. Prehosp Disaster Med. 2018;33(1):98-100.

Monitoring changes in seismic velocity related to an ongoing rapid inflation event at Okmok volcano, Alaska

Science.gov (United States)

Bennington, Ninfa; Haney, Matt; De Angelis, Silvio; Thurber, Clifford; Freymueller, Jeff

2015-01-01

Okmok is one of the most active volcanoes in the Aleutian Arc. In an effort to improve our ability to detect precursory activity leading to eruption at Okmok, we monitor a recent, and possibly ongoing, GPS-inferred rapid inflation event at the volcano using ambient noise interferometry (ANI). Applying this method, we identify changes in seismic velocity outside of Okmok’s caldera, which are related to the hydrologic cycle. Within the caldera, we observe decreases in seismic velocity that are associated with the GPS-inferred rapid inflation event. We also determine temporal changes in waveform decorrelation and show a continual increase in decorrelation rate over the time associated with the rapid inflation event. Themagnitude of relative velocity decreases and decorrelation rate increases are comparable to previous studies at Piton de la Fournaise that associate such changes with increased production of volatiles and/ormagmatic intrusion within the magma reservoir and associated opening of fractures and/or fissures. Notably, the largest decrease in relative velocity occurs along the intrastation path passing nearest to the center of the caldera. This observation, along with equal amplitude relative velocity decreases revealed via analysis of intracaldera autocorrelations, suggests that the inflation sourcemay be located approximately within the center of the caldera and represent recharge of shallow magma storage in this location. Importantly, there is a relative absence of seismicity associated with this and previous rapid inflation events at Okmok. Thus, these ANI results are the first seismic evidence of such rapid inflation at the volcano.

Governance, agricultural intensification, and land sparing in tropical South America

OpenAIRE

CEDDIA Michele Graziano; BARDSLEY N. O.; GOMEZ Y PALOMA Sergio; SEDLACEK S

2014-01-01

In this paper we address two topical questions: How do the quality of governance and agricultural intensification impact on spatial expansion of agriculture? Which aspects of governance are more likely to ensure that agricultural intensification allows sparing land for nature? Using data from the Food and Agriculture Organization, the World Bank, the World Database on Protected Areas, and the Yale Center for Environmental Law and Policy, we estimate a panel data model for six South A...

Intensification of tropical agriculture as seen by satellite

Science.gov (United States)

Galford, G. L.; Michelson, H. C.; Spera, S. A.; Hadnott, B.

2013-12-01

We present case studies from Latin America and Africa on intensification of tropical agriculture. The Brazilian Amazon of the early 2000s experienced intensification and extensification. We use time series analysis of MODIS vegetation indices to track changes in cropping intensity and crop types over time. The state of Mato Grosso is Brazil's leading producer of soy, corn and cotton. Using 250 m MODIS EVI data and a new decision-tree algorithm tuned to phenological patterns characteristic of Mato Grosso's major natural vegetation and crop rotations, we mapped land-cover across the state over 11 growing seasons (2001-2011). Between 2000 and 2011, a majority of the cultivated land in Mato Grosso transitioned from the cultivation of one commercial crop per growing season (soy or cotton) to two commercial crops (a soy crop followed by a corn or cotton crop). Over our study period, the cultivated area of double cropped land in Mato Grosso steadily increased over 6-fold from .46 million hectares to 2.9 million hectares, 92% of which was in a soy-corn double cropping rotation. In the sub-Saharan country of Malawi, 70% of the land is dedicated to food production yet yields of the primary staple crop, maize, have stagnated around 1 ton ha-1 (developed nations' maize yields are 12-16 tons ha-1). Due to the limited land area, improving yields through intensification is a necessary objective of development. Poverty and food insecurity were widespread and persistent for smallholder farmers cultivating less than 1 hectare of land until the implementation of a government intervention, funded through foreign aid, subsidized allocations of fertilizer and improved seed to small farmers. Since implementation of the policy, the number of food insecure, or people in need of food aid, has decreased from 5 million to half a million people. We present indicators that levels of poverty have decreased since the subsidy. National yields have doubled. Applying modified methods from Brazil, we

Photoproduction of events with rapidity gaps between jets with ZEUS at HERA

Energy Technology Data Exchange (ETDEWEB)

Ryan, P.D.

2006-11-15

Cross sections for the photoproduction of dijet events, where the two jets with the highest transverse energy are separated by a large gap in pseudorapidity, have been studied with the ZEUS detector using an integrated luminosity of 38.6 pb{sup -1}. Rapidity-gap events are defined in terms of the energy flow between the jets, such that the total summed transverse energy in this region is less than some value E{sup CUT}{sub T}. The data show a clear excess above the predictions of standard photoproduction models. Models which include color-singlet exchange are able to describe the data. (orig.)

Photoproduction of events with rapidity gaps between jets with ZEUS at HERA

International Nuclear Information System (INIS)

Ryan, P.D.

2006-11-01

Cross sections for the photoproduction of dijet events, where the two jets with the highest transverse energy are separated by a large gap in pseudorapidity, have been studied with the ZEUS detector using an integrated luminosity of 38.6 pb -1 . Rapidity-gap events are defined in terms of the energy flow between the jets, such that the total summed transverse energy in this region is less than some value E CUT T . The data show a clear excess above the predictions of standard photoproduction models. Models which include color-singlet exchange are able to describe the data. (orig.)

Bio-economic household modelling for agricultural intensification

NARCIS (Netherlands)

Kruseman, G.

2000-01-01

This study contributes to the quest for sustainable agricultural intensification through the development of a quantitative bio-economic modelling framework that allows assessment of new technology and policy measures in terms of household welfare and sustainability indicators. The main aim

Change in ocean subsurface environment to suppress tropical cyclone intensification under global warming

Science.gov (United States)

Huang, Ping; Lin, I. -I; Chou, Chia; Huang, Rong-Hui

2015-01-01

Tropical cyclones (TCs) are hazardous natural disasters. Because TC intensification is significantly controlled by atmosphere and ocean environments, changes in these environments may cause changes in TC intensity. Changes in surface and subsurface ocean conditions can both influence a TC's intensification. Regarding global warming, minimal exploration of the subsurface ocean has been undertaken. Here we investigate future subsurface ocean environment changes projected by 22 state-of-the-art climate models and suggest a suppressive effect of subsurface oceans on the intensification of future TCs. Under global warming, the subsurface vertical temperature profile can be sharpened in important TC regions, which may contribute to a stronger ocean coupling (cooling) effect during the intensification of future TCs. Regarding a TC, future subsurface ocean environments may be more suppressive than the existing subsurface ocean environments. This suppressive effect is not spatially uniform and may be weak in certain local areas. PMID:25982028

Actionable knowledge for ecological intensification of agriculture

NARCIS (Netherlands)

Geertsema, W.; Rossing, W.A.H.; Landis, D.A.; Bianchi, F.J.J.A.; van Rijn, P.C.J.; Schaminée, J.H.J.; Tscharntke, T.; van der Werf, W.

2016-01-01

Ecological intensification of agriculture (EI) aims to conserve and promote biodiversity and the sustainable use of associated ecosystem services to support resource-efficient production. In many cases EI requires fundamental changes in farm and landscape management as well as the organizations and

Intensification of Shifting Cultivation in Tanzania: Degree, Drivers and Effects on Vegetation and Soils

DEFF Research Database (Denmark)

Kilawe, Charles Joseph

The aim of the present study was to provide a better understanding of the degree and drivers of intensification of shifting cultivation and its effects on vegetation and soils. The study was conducted in uplands and low lands agro-ecological zones of Kilosa District, eastern central Tanzania. Data...... and intensive short fallow systems. They also adopted intensive land preparation methods that involved deep cultivation and burying of vegetation. Intensification in upland was driven by adoption and enforcement of land tenure policies which restrict shifting cultivation whereas in the lowlands, it was driven...... that sustainable intensification of shifting cultivation be sought to prevent further adverse effects on the environment. The present restrictive policy driven approach of intensification of shifting cultivation seems to cause more negative environmental consequences. I recommend development and promotion...

Eco-efficiency of intensification scenarios for milk production in New Zealand

Energy Technology Data Exchange (ETDEWEB)

Basset-Mens, Claudine; Ledgard, Stewart; Boyes, Mark [AgResearch Limited, Ruakura Research Centre, East Street, Private Bag 3123, Hamilton (New Zealand)

2009-04-15

New Zealand (NZ) dairy farms used to be the lowest input and most efficient dairy farms of the world. However, intensification of the traditional pasture-based system has occurred over the last decade and has not always been accompanied by increased efficiency. The purpose of this paper is to produce an updated reference of the eco-efficiency of NZ dairy farm systems and to analyse the implications of intensification on their eco-efficiency. Results for an average NZ dairy farm system were compared with those for three dairy farmlet systems representing a wide range in intensification practices. A low input system (LI) (no N fertiliser, no brought-in feed supplement, stocking rate of 2.3 cows/ha) was compared with an N-fertilised farm system (NF) (170 kg fertiliser-N/ha/year, 3 cows/ha) representing a first level of intensification and with an N-fertilised and maize silage supplemented system (NFMS) (170 kg fertiliser-N/ha/year, 13 t DM maize silage/ha/year, 5.2 cows/ha), representing a possible future intensification option. Their eco-efficiency in terms of milk production and land use was compared using Life Cycle Assessment (LCA) methodology. NZ dairy farm systems rely on favourable temperate climate conditions and long-term perennial ryegrass/white clover pasture, to achieve eco-efficient milk production and land use compared to European systems. However, intensification of NZ dairy farms was shown to be detrimental to their eco-efficiency in terms both of milk production and land use functions and could greatly reduce their advantage compared to European systems. The eco-efficiency of LI was very high whatever the functional unit which is remarkable from an LCA perspective. NF and NFMS had a similar eco-efficiency except for energy use which corresponded to the most critical hot spot of NFMS. All studied NZ systems presented some areas for improvement where some new technologies available for dairy farms might play a promising role in the future. Finally, it

Mental illness and intensification of diabetes medications: an observational cohort study.

Science.gov (United States)

Frayne, Susan M; Holmes, Tyson H; Berg, Eric; Goldstein, Mary K; Berlowitz, Dan R; Miller, Donald R; Pogach, Leonard M; Laungani, Kaajal J; Lee, Tina T; Moos, Rudolf

2014-10-22

Mental health condition (MHC) comorbidity is associated with lower intensity care in multiple clinical scenarios. However, little is known about the effect of MHC upon clinicians' decisions about intensifying antiglycemic medications in diabetic patients with poor glycemic control. We examined whether delay in intensification of antiglycemic medications in response to an elevated Hemoglobin A1c (HbA1c) value is longer for patients with MHC than for those without MHC, and whether any such effect varies by specific MHC type. In this observational study of diabetic Veterans Health Administration (VA) patients on oral antiglycemics with poor glycemic control (HbA1c ≥8) (N =52,526) identified from national VA databases, we applied Cox regression analysis to examine time to intensification of antiglycemics after an elevated HbA1c value in 2003-2004, by MHC status. Those with MHC were no less likely to receive intensification: adjusted Hazard Ratio [95% CI] 0.99 [0.96-1.03], 1.13 [1.04-1.23], and 1.12 [1.07-1.18] at 0-14, 15-30 and 31-180 days, respectively. However, patients with substance use disorders were less likely than those without substance use disorders to receive intensification in the first two weeks following a high HbA1c, adjusted Hazard Ratio 0.89 [0.81-0.97], controlling for sex, age, medical comorbidity, other specific MHCs, and index HbA1c value. For most MHCs, diabetic patients with MHC in the VA health care system do not appear to receive less aggressive antiglycemic management. However, the subgroup with substance use disorders does appear to have excess likelihood of non-intensification; interventions targeting this high risk subgroup merit attention.

Single-Trial Event-Related Potential Based Rapid Image Triage System

Directory of Open Access Journals (Sweden)

Ke Yu

2011-06-01

Full Text Available Searching for points of interest (POI in large-volume imagery is a challenging problem with few good solutions. In this work, a neural engineering approach called rapid image triage (RIT which could offer about a ten-fold speed up in POI searching is developed. It is essentially a cortically-coupled computer vision technique, whereby the user is presented bursts of images at a speed of 6–15 images per second and then neural signals called event-related potential (ERP is used as the ‘cue’ for user seeing images of high relevance likelihood. Compared to past efforts, the implemented system has several unique features: (1 it applies overlapping frames in image chip preparation, to ensure rapid image triage performance; (2 a novel common spatial-temporal pattern (CSTP algorithm that makes use of both spatial and temporal patterns of ERP topography is proposed for high-accuracy single-trial ERP detection; (3 a weighted version of probabilistic support-vector-machine (SVM is used to address the inherent unbalanced nature of single-trial ERP detection for RIT. High accuracy, fast learning, and real-time capability of the developed system shown on 20 subjects demonstrate the feasibility of a brainmachine integrated rapid image triage system for fast detection of POI from large-volume imagery.

A computer-aided approach for achieving sustainable process design by process intensification

DEFF Research Database (Denmark)

Anantasarn, Nateetorn; Suriyapraphadilok, Uthaiporn; Babi, Deenesh Kavi

2017-01-01

to generate flowsheet alternatives that satisfy the design targets thereby, minimizing and/or eliminating the process hot-spots. The application of the framework is highlighted through the production of para-xylene via toluene methylation where more sustainable flowsheet alternatives that consist of hybrid......Process intensification can be applied to achieve sustainable process design. In this paper, a systematic, 3-stage synthesis-intensification framework is applied to achieve more sustainable design. In stage 1, the synthesis stage, an objective function and design constraints are defined and a base...... case is synthesized. In stage 2, the design and analysis stage, the base case is analyzed using economic and environmental analyses to identify process hot-spots that are translated into design targets. In stage 3, the innovation design stage, phenomena-based process intensification is performed...

Novel flood risk assessment framework for rapid decision making

Science.gov (United States)

Valyrakis, Manousos; Koursari, Eftychia; Solley, Mark

2016-04-01

The impacts of catastrophic flooding, have significantly increased over the last few decades. This is due to primarily the increased urbanisation in ever-expanding mega-cities as well as due to the intensification both in magnitude and frequency of extreme hydrologic events. Herein a novel conceptual framework is presented that incorporates the use of real-time information to inform and update low dimensionality hydraulic models, to allow for rapid decision making towards preventing loss of life and safeguarding critical infrastructure. In particular, a case study from the recent UK floods in the area of Whitesands (Dumfries), is presented to demonstrate the utility of this approach. It is demonstrated that effectively combining a wealth of readily available qualitative information (such as crowdsourced visual documentation or using live data from sensing techniques), with existing quantitative data, can help appropriately update hydraulic models and reduce modelling uncertainties in future flood risk assessments. This approach is even more useful in cases where hydraulic models are limited, do not exist or were not needed before unpredicted dynamic modifications to the river system took place (for example in the case of reduced or eliminated hydraulic capacity due to blockages). The low computational cost and rapid assessment this framework offers, render it promising for innovating in flood management.

Induced intensification: agricultural change in Bangladesh with implications for Malthus and Boserup.

Science.gov (United States)

Turner, B L; Ali, A M

1996-12-10

Bangladesh is dominated by a small-holder agrarian economy under extreme stress. Production shortfalls, increasing economic polarization, and chronic malnutrition are persistent, but major famine has been diverted in part by significant growth in agriculture. This recent history is open to both Malthusian and Boserupian interpretations-a history we explore here through a test of the induced intensification thesis of agricultural change. This thesis, framed by variations in the behavior of small-holders, has grown from a simple demand-production relationship to a consideration of the mediating influences on that relationship. The induced intensification thesis is reviewed and tested for 265 households in 6 villages in Bangladesh from 1950-1986. A time-series analysis of an induced intensification model provides relatively high levels of explained variance in cropping intensity (frequency and land productivity) and also indicates the relative impacts of household class, environment, and cropping strategies. On average, the small-holders in question kept pace with the demands on production, although important class and village variations were evident and the proportion of landless households increased. These results, coupled with evidence that agricultural growth involved intensification thresholds, provide clues about Malthusian and Boserupian interpretations of Bangladesh, and suggest that small-holder agriculture there is likely to continue on a "muted" path of growth.

The Upshear Environment-Outflow Interface of a Sheared, Rapidly Intensifying Tropical Cyclone

Science.gov (United States)

Ryglicki, D.; Doyle, J. D.; Jin, Y.; Hodyss, D.; Viner, K.

2017-12-01

An idealized, simulated tropical cyclone (TC) which undergoes rapid intensification in moderate vertical wind shear is shown to exhibit structural similarities to observed TCs of this class. Due to a complex vortex tilt evolution, enhanced convection causes enhanced outflow from the TC which subsequently serves to block and to divert environmental flow around the TC. This allows for the TC to come back into vertical alignment and undergo rapid intensification. A trajectory analysis indicates that blocking is limited to a narrow range of heights, indicating that the vertical profile of environmental winds is a key factor for permitting this evolution. Satellite observations indicate the presence of upper-level arcs extending upshear beyond the TC. Synthetic satellite imagery of the simulated TC indicates this is the termination of the outflow. Using a Helmholtz decomposition, it is found that the divergent component of the outflow extends 1000 km upshear into the environment, potentially explaining the 1000-km clearing seen in satellite observations.

Phenomena based Methodology for Process Synthesis incorporating Process Intensification

DEFF Research Database (Denmark)

Lutze, Philip; Babi, Deenesh Kavi; Woodley, John

2013-01-01

at processes at the lowest level of aggregation which is the phenomena level. In this paper, a phenomena based synthesis/design methodology incorporating process intensification is presented. Using this methodology, a systematic identification of necessary and desirable (integrated) phenomena as well......Process intensification (PI) has the potential to improve existing as well as conceptual processes, in order to achieve a more sustainable production. PI can be achieved at different levels. That is, the unit operations, functional and/or phenomena level. The highest impact is expected by looking...... as generation and screening of phenomena based flowsheet options are presented using a decomposition based solution approach. The developed methodology as well as necessary tools and supporting methods are highlighted through a case study involving the production of isopropyl-acetate....

Observation of hard scattering in photoproduction events with a large rapidity gap at HERA

International Nuclear Information System (INIS)

Derrick, M.; Krakauer, D.; Magill, S.

1994-11-01

Events with a large rapidity gap and total transverse energy greater than 5 GeV have been observed in quasi-real photoproduction at HERA with the ZEUS detector. The distribution of these events as a function of the γp centre of mass energy is consistent with diffractive scattering. For total transverse energies above 12 GeV, the hadronic final states show predominantly a two-jet structure with each jet having a transverse energy greater than 4 GeV. For the two-jet events, little energy flow is found outside the jets. This observation is consistent with the hard scattering of a quasi-real photon with a colourless object in the proton. (orig.)

Smallholder Farms and the Potential for Sustainable Intensification.

Science.gov (United States)

Mungai, Leah M; Snapp, Sieglinde; Messina, Joseph P; Chikowo, Regis; Smith, Alex; Anders, Erin; Richardson, Robert B; Li, Guiying

2016-01-01

The sustainable intensification of African agriculture is gaining momentum with the compelling need to increase food and agricultural production. In Southern Africa, smallholder farming systems are predominately maize-based and subject to erratic climatic conditions. Farmer crop and soil management decisions are influenced by a plethora of complex factors such as market access resource availability, social relations, environment, and various messages on sustainable farming practices. Such factors pose barriers to increasing sustainable intensification in Africa. This paper characterizes smallholder farming practices in Central Malawi, at Africa Research in Sustainable Intensification for the Next Generation (Africa RISING) project sites. We present findings from a survey of 324 farmers, located within four Africa RISING sites selected in a stratified random manner to represent (1) low agricultural potential (high evapotranspiration, variable rainfall), (2) medium agricultural potential (two sites), and (3) high agricultural potential (well-distributed rainfall). Soil fertility was low overall, and certain farming practices appeared to limit the sustainability of agricultural production. Nearly half of farmers did not value legume residues as a high nutrient value resource for soil amelioration, as legume residues were removed (17.9%) or burned (21.4%). Conversely, maize residues were rarely removed (4.5%) or burned (10.4%). We found that farmers do not allocate soil amendment resources to legume fields (zero instances of mineral fertilizer or manure application to legumes compared to 88 and 22% of maize systems, respectively). Policy makers in Malawi have led initiatives to intensify agricultural systems through subsidizing farmer access to mineral fertilizer as well as maize hybrid seed, and only rarely to improved legume seed. In this survey, farmers allocate mineral fertilizer to maize systems and not legume systems. There is urgent need to invest in education

Smallholder Farms and the Potential for Sustainable Intensification

Directory of Open Access Journals (Sweden)

Leah M Mungai

2016-11-01

Full Text Available The sustainable intensification of African agriculture is gaining momentum with the compelling need to increase food and agricultural production. In Southern Africa, smallholder farming systems are predominately maize-based and subject to erratic climatic conditions. Farmer crop and soil management decisions are influenced by a plethora of complex factors such as market access resource availability, social relations, environment and various messages on sustainable farming practices. Such factors pose barriers to increasing sustainable intensification in Africa. This paper characterizes smallholder farming practices in Central Malawi, at Africa Research in Sustainable Intensification for the Next Generation (Africa RISING project sites. We present findings from a survey of 324 farmers, located within four Africa RISING sites selected in a stratified random manner to represent (1 low agricultural potential (high evapotranspiration, variable rainfall, (2 medium agricultural potential (two sites, and (3 high agricultural potential (well distributed rainfall. Soil fertility was low overall, and certain farming practices appeared to limit the sustainability of agricultural production. Nearly half of farmers did not value legume residues as a high nutrient value resource for soil amelioration, as legume residues were removed (17.9% or burned (21.4%. Conversely, maize residues were rarely removed (4.5% or burned (10.4%. We found that farmers do not allocate soil amendment resources to legume fields (zero instances of mineral fertilizer or manure application to legumes compared to 88% and 22% of maize systems, respectively. Policy makers in Malawi have led initiatives to intensify agricultural systems through subsidizing farmer access to mineral fertilizer as well as maize hybrid seed, and only rarely to improved legume seed. In this survey, farmers allocate mineral fertilizer to maize systems and not legume systems. There is urgent need to invest in

What next after basal insulin? Treatment intensification with lixisenatide in Asian patients with type 2 diabetes mellitus.

Science.gov (United States)

Chan, Wing B; Luk, Andrea; Chow, Wing S; Yeung, Vincent T F

2017-06-01

There is increasing evidence that the pathophysiology of type 2 diabetes mellitus (T2DM) in Asian patients differs from that in Western patients, with early phase insulin deficiencies, increased postprandial glucose excursions, and increased sensitivity to insulin. Asian patients may also experience higher rates of gastrointestinal adverse events associated with glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as nausea and vomiting, compared with their Western counterparts. These factors should be taken into consideration when selecting therapy for basal insulin treatment intensification in Asian patients. However, the majority of studies to establish various agents for treatment intensification in T2DM have been conducted in predominantly Western populations, and the levels of evidence available in Chinese or Asian patients are limited. This review discusses the different mechanisms of action of short-acting, prandial, and long-acting GLP-1RAs in addressing hyperglycemia, and describes the rationale and available clinical data for basal insulin in combination with the short-acting prandial GLP-1RA lixisenatide, with a focus on treatment of Asian patients with T2DM. © 2016 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.

Coupled social and ecological outcomes of agricultural intensification in Costa Rica and the future of biodiversity conservation in tropical agricultural regions

Science.gov (United States)

Sanfiorenzo, A. R.; Waits, L.; Finegan, B.; Shaver, I.; Chain Guadarrama, A.; Cleary, K.; Santiago-Garcia, R.; Hormel, L.; Vierling, L. A.; Bosque-Perez, N.; DeClerck, F.; Fagan, M. E.; Sibelet, N.

2016-12-01

Tropical ecosystem conversion to agriculture has caused widespread habitat loss and created fragmented landscapes composed of remnant forest patches embedded in a matrix of agricultural land uses. Non-traditional agricultural export (NTAE) crops such as pineapple are rapidly replacing multiuse landscapes characterized by a diverse matrix of pasture and smallholder crops with intensive, large-scale, monoculture plantations. Using an interdisciplinary approach, we examine the coupled social and ecological implications of agricultural intensification Guided by frameworks from political economy, landscape ecology and landscape genetics we: (1) describe the social and economic implications of pineapple expansion, specifically the concentration of land, labor and financial resources, (2) quantify pineapple cultivation's spatial characteristics, and (3) assess the effects of pineapple expansion on surrounding forest ecosystems, on the agricultural matrix and on biodiversity conservation. Our results indicate that pineapple production concentrates land, labor, and financial resources, which has a homogenizing effect on the agricultural economy in the study region. This constrains farm-based livelihoods, with larger implications for food security and agricultural diversity. Landscape ecology and genetics analyses further reveal how pineapple production simplifies and homogenizes the agricultural matrix between forest patches, which increase the genetic structure and reduce the genetic diversity of Symphonia globulifera a forest understory tree species. To offset the effects of agricultural intensification on social and environmental systems, we recommend developing landscape level land use planning capacity. Furthermore, agricultural and conservation policy reform is needed to promote landscape heterogeneity and economic diversity within the agricultural sector. Our interdisciplinary research provides a detailed examination of the social and ecological impacts of

Observation of hard processes in rapidity gap events in {gamma}p interactions at HERA

Energy Technology Data Exchange (ETDEWEB)

Ahmed, T.; Aid, S.; Andreev, V.; Andrieu, B.; Appuhn, R.D.; Arpagaus, M.; Babaev, A.; Baehr, J.; Ban, J.; Baranov, P.; Barrelet, E.; Bartel, W.; Barth, M.; Bassler, U.; Beck, H.P.; Behrend, H.J.; Belousov, A.; Berger, C.; Bergstein, H.; Bernardi, G.; Bernet, R.; Bertrand-Coremans, G.; Besancon, M.; Beyer, R.; Biddulph, P.; Bizot, J.C.; Blobel, V.; Borras, K.; Botterweck, F.; Boudry, V.; Braemer, A.; Brasse, F.; Braunschweig, W.; Brisson, V.; Bruncko, D.; Brune, C.; Buchholz, R.; Buengener, L.; Buerger, J.; Buesser, F.W.; Buniatian, A.; Burke, S.; Buschhorn, G.; Campbell, A.J.; Carli, T.; Charles, F.; Clarke, D.; Clegg, A.B.; Clerbaux, B.; Colombo, M.; Contreras, J.G.; Coughlan, J.A.; Courau, A.; Coutures, C.; Cozzika, G.; Criegee, L.; Cussans, D.G.; Cvach, J.; Dagoret, S.; Dainton, J.B.; Danilov, M.; Dau, W.D.; Daum, K.; David, M.; Deffur, E.; Delcourt, B.; Del Buono, L.; De Roeck, A.; De Wolf, E.A.; Di Nezza, P.; Dollfus, C.; Dowell, J.D.; Dreis, H.B.; Droutskoi, V.; Duboc, J.; Duellmann, D.; Duenger, O.; Duhm, H.; Ebert, J.; Ebert, T.R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Ehrlichmann, H.; Eichenberger, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellison, R.J.; Elsen, E.; Erdmann, M.; Erdmann, W.; Evrard, E.; Favart, L.; Fedotov, A.; Feeken, D.; Felst, R.; Feltesse, J.; Ferencei, J.; Ferrarotto, F.; Flamm, K.; Fleischer, M.; Flieser, M.; Fluegge, G.; Fomenko, A.; Fominykh, B.; Forbush, M.; Formanek, J.; Foster, J.M.; Franke, G.; Fretwurst, E.; Gabathuler, E.; Gabathuler, K.; Gamerdinger, K.; Garvey, J.; Gayler, J.; Gebauer, M.; Gellrich, A.; Genzel, H.; Gerhards, R.; Goerlach, U.; Goerlich, L.; Gogitidze, N.; Goldberg, M.; Goldner, D.; Gonzalez-Pineiro, B.; Goodall, A.M.; Gorelov, I.; Goritchev, P.; Grab, C.; Graessler, H.; Graessler, R.; Greenshaw, T.; Grindhammer, G.; Gruber, A.; Gruber, C.; Haack, J.; Haidt, D.; Hajduk, L.; Hamon, O.; Hampel, M.; Hanlon, E.M.; Hapke, M.; Haynes, W.J.; Heatherington, J.; Heinzelmann, G.; Henderson, R.C.W.; H1 Collaboration

1995-02-06

Events with no hadronic energy flow in a large interval of pseudo-rapidity in the proton direction are observed in photon-proton interactions at an average centre of mass energy left angle {radical}(s{sub {gamma}p}) right angle of 200 GeV. These events are interpreted as photon diffractive dissociation. Evidence for hard scattering in photon diffractive dissociation is demonstrated using inclusive single particle spectra, thrust as a function of transverse energy, and the observation of jet production. The data can be described by a Monte Carlo calculation including hard photon-pomeron scattering. ((orig.))

Modelling farmers’ decisions on adoption and intensification of improved cowpea seeds in Niger

Directory of Open Access Journals (Sweden)

O.H. Issoufou

2018-01-01

Full Text Available In Niger, global change leads farmers increasingly to intensify their agricultural production. That is one of the reason improved seeds have been diffused among farmers since decades. The study uses Logit and Tobit software for modeling farmers’ decision on adoption and intensification of improved cowpea seeds. The sample consisted of 612 agricultural households selected by random sampling without replacement in 16 villages. Data was collected in 2015 to 2016 through individual survey and focus group. The results show that the rate of improved cowpea seed adoption is 39.7% after three years of introduction. The accessibility of village, age and availability, accessibility of seeds determine at the same time decisions of adoption and intensification of improved cowpea seeds. The probability of improved seeds adoption is determined by education, access to agricultural extension and adaptability, productivity of seeds. Crops Risk perception and preference, precocity of seeds only affect the intensification probability. The analysis of marginal effects shows that adoption probability increases for accessibility of village, education, access to agricultural extension and adaptability, availability and productivity of improved seeds. On the other hand, the probability decreases for age and the availability of seed. Looking at also the marginal effects on seed intensification, it was observed that the probability increases for accessibility of village, perception of production risk and preference, availability and precocity of improved seeds. However, this probability decreases for age and seeds accessibility. These determinants of adoption and intensification are essential for improved seeds dissemination action to enhance the rate of adoption, intensity of seeds use, impact and sustainability for producers.

Rapid depressurization event analysis in BWR/6 using RELAP5 and contain

Energy Technology Data Exchange (ETDEWEB)

Mueftueoglu, A.K.; Feltus, M.A. [Pennsylvania State Univ., University Park, PA (United States)

1995-09-01

Noncondensable gases may become dissolved in Boiling Water Reactor (BWR) water level instrumentation during normal operations. Any dissolved noncondensable gases inside these water columns may come out of solution during rapid depressurization events, and displace water from the reference leg piping resulting in a false high level. These water level errors may cause a delay or failure in actuation, or premature shutdown of the Emergency Core Cooling System. (ECCS). If a rapid depressurization causes an erroneously high water level, preventing automatic ECCS actuation, it becomes important to determine if there would be other adequate indications for operator response and other signals for automatic actuation such as high drywell pressure. It is also important to determine the effect of the level signal on ECCS operation after it is being actuated. The objective of this study is to determine the detailed coupled containment/NSSS response during this rapid depressurization events in BWR/6. The selected scenarios involve: (a) inadvertent opening of all ADS valves, (b) design basis (DB) large break loss of coolant accident (LOCA), and (c) main steam line break (MSLB). The transient behaviors are evaluated in terms of: (a) vessel pressure and collapsed water level response, (b) specific transient boundary conditions, (e.g., scram, MSIV closure timing, feedwater flow, and break blowdown rates), (c) ECCS initiation timing, (d) impact of operator actions, (e) whether indications besides low-low water level were available. The results of the analysis had shown that there would be signals to actuate ECCS other than low reactor level, such as high drywell pressure, low vessel pressure, high suppression pool temperature, and that the plant operators would have significant indications to actuate ECCS.

Impact of agricultural intensification on poverty alleviation among rural farm households in Imo state Nigeria

Directory of Open Access Journals (Sweden)

Iheke, O.R.

2013-12-01

Full Text Available This study was on the impact of agricultural intensification on poverty alleviation among rural farm households in Imo State Nigeria. Multi-stage random sampling and purposive sampling technique was used in choosing the samples used for the study. Data collections were by the use of structured questionnaire and interview schedules and data analysis involved the computation per capital household food expenditure and mean per capita household expenditure so as to draw the poverty line and hence derive the poverty status of the respondents, regression analysis as well as computation of the Chow’s statistic. The results of data analysis revealed that poverty is more pronounced with the farm households that are not practicing agricultural intensification. The significant factors influencing the poverty level of the farmers practicing agricultural intensification were sex of household head, years of formal education, assets endowment, and income; while for the farmers not practicing intensification, household size, years of formal education, assets endowment, and income were the significant factors influencing their poverty level. For the two households, age, years of formal education, assets endowment, and income were the significant factors influencing their poverty level. Education, income and the dummy variable indicating intensification status were the significant factors influencing their poverty level for the entire household with a dummy introduced. The Chow’s test revealed that agricultual intensification has a positive and significant impact on poverty reduction. Therefore, creation of awareness and persuading rural farming households to practice more of intensified agriculture would lead increase in productivity and income with a multiplier effect on poverty reduction.

Introduction to basic concepts and elements in process synthesis and process intensification

DEFF Research Database (Denmark)

Rong, Ben-Guang

2017-01-01

In this chapter, we introduce some basic concepts and elements for process synthesis (PS) and process intensification (PI). These basic concepts and elements are taken partially from distillation systems synthesis and intensification, as described in Chapter 2. In Chapter 2,we present six distill...... these common concepts and elements in the context of general PS and PI works. We hope that at least some of the concepts and elements can be examined and addressed in the methodological approaches for PS and PI....

Rapid Analysis of Eukaryotic Bioluminescence to Assess Potential Groundwater Contamination Events

Directory of Open Access Journals (Sweden)

Zacariah L. Hildenbrand

2015-01-01

Full Text Available Here we present data using a bioluminescent dinoflagellate, Pyrocystis lunula, in a toxicological bioassay to rapidly assess potential instances of groundwater contamination associated with natural gas extraction. P. lunula bioluminescence can be quantified using spectrophotometry as a measurement of organismal viability, with normal bioluminescent output declining with increasing concentration(s of aqueous toxicants. Glutaraldehyde and hydrochloric acid (HCl, components used in hydraulic fracturing and shale acidization, triggered significant toxicological responses in as little as 4 h. Conversely, P. lunula was not affected by the presence of arsenic, selenium, barium, and strontium, naturally occurring heavy metal ions potentially associated with unconventional drilling activities. If exogenous compounds, such as glutaraldehyde and HCl, are thought to have been introduced into groundwater, quantification of P. lunula bioluminescence after exposure to water samples can serve as a cost-effective detection and risk assessment tool to rapidly assess the impact of putative contamination events attributed to unconventional drilling activity.

Observed magnified runoff response to rainfall intensification under global warming

International Nuclear Information System (INIS)

Huang, Jr-Chuan; Lee, Tsung-Yu; Lee, Jun-Yi

2014-01-01

Runoff response to rainfall intensification under global warming is crucial, but is poorly discussed due to the limited data length and human alteration. Historical rainfall and runoff records in pristine catchments in Taiwan were investigated through trend analysis and cross temperature difference analysis. Trend analysis showed that both rainfall and runoff in the 99.9-percentile have been significantly increasing in terms of frequency and intensity over the past four decades. Cross temperature difference analysis quantified that the rainfall and runoff extremes (including the 99.0–99.9-percentiles) may increase by 69.5% and 99.8%, respectively, under a future scenario of 1  ° C increase in temperature. This increase in intensity resembles the increase in intensity observed between 1971–1990 and 1991–2010. The amplified runoff response can be related to the limited catchment storage capacity being preoccupied by rainfall extremes. The quantified temperature effect on rainfall and runoff intensification can be a strong basis for designing scenarios, confirming and fusing GCMs’ results. In addition, the runoff amplification should be a warning for other regions with significant rainfall intensification. Appropriate strategies are indispensable and urgently needed to maintain and protect the development of societies. (paper)

Light field intensification induced by nanoinclusions in optical thin-films

International Nuclear Information System (INIS)

Zhu Zhiwu; Cheng Xiangai; Huang Liangjin; Liu Zejin

2012-01-01

Inclusions even in tens of nanometers scale (nanoinclusion) can cause electric field intensifications locally in an optical thin-film when irradiated by laser. It was modeled by using finite element analysis, and the dependences of local light field on complex refractive index, diameter and embedded depth of the nanoinclusion were simulated. In addition, the average light intensity inside the nanodefect was calculated as well as the energy deposition rate. The modeling results show that extinction coefficient of a nanoinclusion has more significant effects on local light field than real part of the refractive index. A light intensification as large as 4× can occur owing to a metallic nanoinclusion and the peaks of electric field distribution locating on the boundary of the particulate. Energy deposition rate, reflecting the behavior of laser induced damage to the thin-film, is found to have the highest value at a certain extinction coefficient, instead of the state that, for a defect, a higher extinction coefficient causes a higher speed of laser absorption. And when this coefficient is relatively small, the energy deposition rate grows linearly with it. Finally, regarding high absorptive nanoinclusions, the larger can induce stronger laser intensification and higher average of energy deposition rate, whereas no significant difference is made by low absorptive nanoinclusions of different sizes.

On the Intensification of Information Protection Processes

Directory of Open Access Journals (Sweden)

A. A. Malyuk

2011-03-01

Full Text Available The features of the information protection task solution in its modern statement as a complex problem that encompasses all aspects of information technology development are discussed. Such an interpretation would inevitably lead to an increase of the role of the systemic problems solution of which relies on advanced scientific and methodological basis, so called information protection processes’ intensification.

Costs, Benefits and Challenges of Sustainable Livestock Intensification in a Major Deforestation Frontier in the Brazilian Amazon

Directory of Open Access Journals (Sweden)

Edenise Garcia

2017-01-01

Full Text Available Extensive livestock production is a major deforestation driver in the Brazilian Amazon. This study presents an assessment of the economic and environmental feasibility of sustainable livestock intensification in São Félix do Xingu municipality, a deforestation frontier with an area of more than 8.5 million hectares, and home to the largest cattle herd in Brazil. Proposed intensification was limited to approximately three animal units per hectare to avoid negative environmental impacts. Transition costs to sustainable cattle intensification were estimated for thirteen pilot farms taking into account adoption of good agriculture practices, pasture maintenance/restoration, and restoration of environmental liabilities. To move to sustainable intensification practices, a mean total annual investment of US$1335/ha ± US$619/ha would be necessary, varying from US$750 to US$2595/ha. Internal rate of return and net present value estimates indicated that the sustainable livestock intensification approach proposed was profitable in farms with more than 400 hectares of pastureland, but not in those where the pasture areas were smaller than 150 hectares. Livestock sustainable intensification also had the potential to promote social and environmental benefits, including a 54% increase in the number of contract workers, improvement of landowners’ managerial skills, and workers’ training, in addition to avoiding emission of 1.9 Mt CO2eq and sequestration of 0.36 Mt CO2eq. We conclude that the sustainable intensification of pasture areas has the potential to prevent further deforestation in the Amazon while generating social and other environmental benefits.

Zoonosis emergence linked to agricultural intensification and environmental change.

Science.gov (United States)

Jones, Bryony A; Grace, Delia; Kock, Richard; Alonso, Silvia; Rushton, Jonathan; Said, Mohammed Y; McKeever, Declan; Mutua, Florence; Young, Jarrah; McDermott, John; Pfeiffer, Dirk Udo

2013-05-21

A systematic review was conducted by a multidisciplinary team to analyze qualitatively best available scientific evidence on the effect of agricultural intensification and environmental changes on the risk of zoonoses for which there are epidemiological interactions between wildlife and livestock. The study found several examples in which agricultural intensification and/or environmental change were associated with an increased risk of zoonotic disease emergence, driven by the impact of an expanding human population and changing human behavior on the environment. We conclude that the rate of future zoonotic disease emergence or reemergence will be closely linked to the evolution of the agriculture-environment nexus. However, available research inadequately addresses the complexity and interrelatedness of environmental, biological, economic, and social dimensions of zoonotic pathogen emergence, which significantly limits our ability to predict, prevent, and respond to zoonotic disease emergence.

Tropical vegetation evidence for rapid sea level changes associated with Heinrich Events

Energy Technology Data Exchange (ETDEWEB)

Gonzalez, Catalina; Dupont, Lydie M, E-mail: catalina@uni-bremen.d, E-mail: dupont@uni-bremen.d [MARUM - Centre for Marine Environmental Sciences, University of Bremen, Leobener Strasse, D-28359 Germany (Germany)

2010-03-15

A Cariaco Basin pollen record shows the development of tropical salt marshes during marine isotope stage 3. Rapid and abrupt expansions of salt marsh vegetation in tropical South America are associated with north Atlantic Heinrich Events stadials (HE-stadials). Intervals of salt marsh expansion have an internal structure, which consists of a recurrent alternation of species that starts with pollen increments of Chenopodiaceae, that are followed by increments of grasses, and subsequently by increments of Cyperaceae. This pattern suggests a successional process that is determined by the close relationship between sea-level and plant community dynamics. The salt tolerant Chenopodiaceae, indicate hypersaline intertidal environments, which were most likely promoted by extremely dry atmospheric conditions. Rapid sea-level rise characterizes the onset of HE-stadials, causing the continued recruitment of pioneer species, which are the only ones tolerating rapid rates of disturbance. Once sea-level rise decelerates, marsh plants are able to trap and stabilize sediments, favouring the establishment of more competitive species. These results add to the scarce knowledge on the dynamics of tropical salt marsh ecosystems, and provide independent paleoclimatic evidence on sea-level changes following Antarctic climate variability.

Weakened cyclones, intensified anticyclones and recent extreme cold winter weather events in Eurasia

International Nuclear Information System (INIS)

Zhang Xiangdong; Lu Chuhan; Guan Zhaoyong

2012-01-01

Extreme cold winter weather events over Eurasia have occurred more frequently in recent years in spite of a warming global climate. To gain further insight into this regional mismatch with the global mean warming trend, we analyzed winter cyclone and anticyclone activities, and their interplay with the regional atmospheric circulation pattern characterized by the semi-permanent Siberian high. We found a persistent weakening of both cyclones and anticyclones between the 1990s and early 2000s, and a pronounced intensification of anticyclone activity afterwards. It is suggested that this intensified anticyclone activity drives the substantially strengthening and northwestward shifting/expanding Siberian high, and explains the decreased midlatitude Eurasian surface air temperature and the increased frequency of cold weather events. The weakened tropospheric midlatitude westerlies in the context of the intensified anticyclones would reduce the eastward propagation speed of Rossby waves, favoring persistence and further intensification of surface anticyclone systems. (letter)

Observation of events with a large rapidity gap in deep inelastic scattering at HERA

International Nuclear Information System (INIS)

Derrick, M.; Krakauer, D.; Magill, S.

1993-07-01

In deep inelastic, neutral current scattering of electrons and protons at √s=296 GeV, we observe in the ZEUS detector events with a large rapidity gap in the hadronic final state. They occur in the region of small Bjorken x and are observed up to Q 2 of 100 GeV 2 . They account for about 5% of the events with Q 2 ≥10 GeV 2 . Their general properties are inconsistent with the dominant mechanism of deep inelastic scattering, where color is transferred between the scattered quark and the proton remnant, and suggest that the underlying production mechanism is the diffractive dissociation of the virtual photon. (orig.)

Rapidity distributions in exclusive Z + jet and photon + jet events in pp collisions at sqrt(s) = 7 TeV

Energy Technology Data Exchange (ETDEWEB)

Chatrchyan, Serguei; et al.,

2013-12-23

Rapidity distributions are presented for events containing either a Z boson or a photon with a single jet in proton-proton collisions produced at the CERN LHC. The data, collected with the CMS detector at \\sqrt{s} = 7 TeV, correspond to an integrated luminosity of 5.0 inverse femtobarns. The individual rapidity distributions of the boson and the jet are consistent within 5% with expectations from perturbative QCD. However, QCD predictions for the sum and the difference in rapidities of the two final-state objects show discrepancies with CMS data. In particular, next-to-leading-order QCD calculations, and two common Monte Carlo event generators using different methods to match matrix-element partons with parton showers, appear inconsistent with the data as well as with each other.

Response of ground-nesting farmland birds to agricultural intensification across Europe: Landscape and field level management factors

NARCIS (Netherlands)

Guerrero, I.; Morales, M.B.; Onate, J.J.; Geiger, F.; Berendse, F.; Snoo, de G.R.

2012-01-01

European farmland bird populations have decreased dramatically in recent decades and agricultural intensification has been identified as the main cause contributing to these declines. Identifying which specific intensification pressures are driving those population trends seems vital for bird

Opportunities and challenges for process control in process intensification

NARCIS (Netherlands)

Nikacevic, N.M.; Huesman, A.E.M.; Hof, Van den P.M.J.; Stankiewicz, A.

2012-01-01

This is a review and position article discussing the role and prospective for process control in process intensification. Firstly, the article outlines the classical role of control in process systems, presenting an overview of control systems’ development, from basic PID control to the advanced

Phase 2 Neoadjuvant Treatment Intensification Trials in Rectal Cancer

DEFF Research Database (Denmark)

Teo, Mark T W; McParland, Lucy; Appelt, Ane L

2018-01-01

PURPOSE: Multiple phase 2 trials of neoadjuvant treatment intensification in locally advanced rectal cancer have reported promising efficacy signals, but these have not translated into improved cancer outcomes in phase 3 trials. Improvements in phase 2 trial design are needed to reduce these fals...

Agricultural Intensification as a Mechanism of Adaptation to Climate Change Impacts

Science.gov (United States)

Kyle, P.; Calvin, K. V.; le Page, Y.; Patel, P.; West, T. O.; Wise, M. A.

2015-12-01

The research, policy, and NGO communities have devoted significant attention to the potential for agricultural intensification, or closure of "yield gaps," to alleviate future global hunger, poverty, climate change impacts, and other threats. However, because the research to this point has focused on biophysically attainable yields—assuming optimal choices under ideal conditions—the presently available work has not yet addressed the likely responses of the agricultural sector to real-world conditions in the future. This study investigates endogenous agricultural intensification in response to global climate change impacts—that is, intensification independent of policies or other exogenous interventions to promote yield gap closure. The framework for the analysis is a set of scenarios to 2100 in the GCAM global integrated assessment model, enhanced to include endogenous irrigation, fertilizer application, and yields, in each of 283 land use regions, with maximum yields based on the 95th percentile of attainable yields in a recent global assessment. We assess three levels of agricultural climate impacts, using recent global gridded crop model datasets: none, low (LPJmL), and high (Pegasus). Applying formulations for decomposition of climate change impacts response developed in prior AgMIP work, we find that at the global level, availability of high-yielding technologies mitigates price shocks and shifts the agricultural sector's climate response modestly towards intensification, away from cropland expansion and reduced production. At the regional level, the behavior is more complex; nevertheless, availability of high-yielding production technologies enhances the inter-regional shifts in agricultural production that are induced by climate change, complemented by commensurate changes in trade patterns. The results highlight the importance of policies to facilitate yield gap closure and inter-regional trade as mechanisms for adapting to climate change

Ecological intensification to mitigate impacts of conventional intensive land use on pollinators and pollination.

Science.gov (United States)

Kovács-Hostyánszki, Anikó; Espíndola, Anahí; Vanbergen, Adam J; Settele, Josef; Kremen, Claire; Dicks, Lynn V

2017-05-01

Worldwide, human appropriation of ecosystems is disrupting plant-pollinator communities and pollination function through habitat conversion and landscape homogenisation. Conversion to agriculture is destroying and degrading semi-natural ecosystems while conventional land-use intensification (e.g. industrial management of large-scale monocultures with high chemical inputs) homogenises landscape structure and quality. Together, these anthropogenic processes reduce the connectivity of populations and erode floral and nesting resources to undermine pollinator abundance and diversity, and ultimately pollination services. Ecological intensification of agriculture represents a strategic alternative to ameliorate these drivers of pollinator decline while supporting sustainable food production, by promoting biodiversity beneficial to agricultural production through management practices such as intercropping, crop rotations, farm-level diversification and reduced agrochemical use. We critically evaluate its potential to address and reverse the land use and management trends currently degrading pollinator communities and potentially causing widespread pollination deficits. We find that many of the practices that constitute ecological intensification can contribute to mitigating the drivers of pollinator decline. Our findings support ecological intensification as a solution to pollinator declines, and we discuss ways to promote it in agricultural policy and practice. © 2017 The Authors. Ecology Letters published by CNRS and John Wiley & Sons Ltd.

Matrix intensification alters avian functional group composition in adjacent rainforest fragments.

Directory of Open Access Journals (Sweden)

Justus P Deikumah

Full Text Available Conversion of farmland land-use matrices to surface mining is an increasing threat to the habitat quality of forest remnants and their constituent biota, with consequences for ecosystem functionality. We evaluated the effects of matrix type on bird community composition and the abundance and evenness within avian functional groups in south-west Ghana. We hypothesized that surface mining near remnants may result in a shift in functional composition of avifaunal communities, potentially disrupting ecological processes within tropical forest ecosystems. Matrix intensification and proximity to the remnant edge strongly influenced the abundance of members of several functional guilds. Obligate frugivores, strict terrestrial insectivores, lower and upper strata birds, and insect gleaners were most negatively affected by adjacent mining matrices, suggesting certain ecosystem processes such as seed dispersal may be disrupted by landscape change in this region. Evenness of these functional guilds was also lower in remnants adjacent to surface mining, regardless of the distance from remnant edge, with the exception of strict terrestrial insectivores. These shifts suggest matrix intensification can influence avian functional group composition and related ecosystem-level processes in adjacent forest remnants. The management of matrix habitat quality near and within mine concessions is important for improving efforts to preserveavian biodiversity in landscapes undergoing intensification such as through increased surface mining.

Spider diversity in coffee agroecosystems: the influence of agricultural intensification and aggressive ants.

Science.gov (United States)

Marín, Linda; Perfecto, Ivette

2013-04-01

Spiders are a very diverse group of invertebrate predators found in agroecosystems and natural systems. However, spider distribution, abundance, and eventually their ecological function in ecosystems can be influenced by abiotic and biotic factors such as agricultural intensification and dominant ants. Here we explore the influence of both agricultural intensification and the dominant arboreal ant Azteca instabilis on the spider community in coffee agroecosystems in southern Mexico. To measure the influence of the arboreal ant Azteca instabilis (F. Smith) on the spider community inhabiting the coffee layer of coffee agroecosystems, spiders were collected from coffee plants that were and were not patrolled by the ant in sites differing in agricultural intensification. For 2008, generalized linear mixed models showed that spider diversity was affected positively by agricultural intensification but not by the ant. However, results suggested that some spider species were associated with A. instabilis. Therefore, in 2009 we concentrated our research on the effect of A. instabilis on spider diversity and composition. For 2009, generalized linear mixed models show that spider richness and abundance per plant were significantly higher in the presence of A. instabilis. In addition, analyses of visual counts of insects and sticky traps data show that more resources were present in plants patrolled by the ant. The positive effect of A. instabilis on spiders seems to be caused by at least two mechanisms: high abundance of insects and protection against predators.

Fishery intensification in small water bodies: a review for North America

National Research Council Canada - National Science Library

Moehl, John Frederic; Davies, William D

1993-01-01

.... Intensification is also achieved by enhancing water fertility through liming and fertilization. Case studies are presented representing contrasting climatic regions of North America while demonstrating similarities in management style...

Transition-zone observations of rapid flare events as observed by OSO-8

Science.gov (United States)

Lites, B. W.

1981-01-01

The rapid dissipation of flare energy has been observed in the transition-zone line of C IV at 1548.2 A using the University of Colorado spectrometer aboard OSO-8. Impulsive brightenings have been resolved with characteristic rise times as low as 3.5s. One event is analyzed in detail, and it is inferred that the electron density is greater than 2 x 10 to the 11th/cu cm at a temperature of 60,000 K, and that the flare energy is deposited at a rate of 2 ergs/cu cm per sec or greater. The temporal behavior of the intensity at the center of the C IV line is consistent with a nonequilibrium ionization of C III through C V. If this event is a result of the multiple tearing mode instability as the primary energy release mechanism, then the observations indicate a preflare magnetic field of about 175 G.

Edouard's (2014) Intensification: An Investigation of Precipitation and Thermodynamic Symmetrization Using a Cloud-Resolving Ensemble

Science.gov (United States)

Alvey, G., III; Zipser, E. J.

2017-12-01

Literature over the past 10 years has provided conflicting views about the relative importance of precipitation symmetry and convective intensity for tropical cyclone intensification. While several modeling studies (Braun et al. 2006, Guimond et al. 2010, Molinari et al. 2013, Rogers et al. 2013, 2015) have favored intense deep convection, satellite-based composite studies, on the other hand, have offered a differing pathway towards tropical cyclone intensification emphasizing shallow to moderate precipitation (Zagrodnik and Jiang 2014, Tao and Jiang 2015, Alvey et al. 2015). This has left fundamental questions unanswered regarding the relationships between precipitation and TC intensity change: What are the dominant precipitation types, their spatial distributions, and the timing of these features with respect to intensification? And what causes precipitation to symmetrize and increase in the upshear quadrants? One potentially important process, the humidification of upshear quadrants, has been identified to occur nearly coincidental with increased precipitation symmetry prior to and during Edouard's (2014) intensification (Zawislak et al. 2016). While observations from the Global Hawk and P-3 provided important snapshots throughout the life cycle of Edouard (2014), numerical simulations complement and reveal, in more detail, the processes behind these relationships through filling an 48-hour airborne observational gap during a crucial period of intensification between 12-14 Sept. We use a high resolution, full physics ensemble of Edouard (2014) simulated by the Weather Research and Forecasting (WRF) model - Advanced Research WRF (ARW; Skamarock et al., 2008). We deem the quantification of azimuthal variations — with a focus on the shear-relative quadrants — as particularly important, especially early in intensification when thermodynamic and precipitation distributions tend to be more asymmetric. Using a water vapor budget and trajectories we examine whether

Achieving More Sustainable Designs through a Process Synthesis-Intensification Framework

DEFF Research Database (Denmark)

Babi, Deenesh Kavi; Woodley, John; Gani, Rafiqul

2014-01-01

More sustainable process designs refer to design alternatives that correspond to lowervalues of a set of targeted performance criteria. In this paper, a multi-level frameworkfor process synthesis-intensification that leads to more sustainable process designs ispresented. At the highest level of a...

Patterns of land use, extensification, and intensification of Brazilian agriculture.

Science.gov (United States)

Dias, Lívia C P; Pimenta, Fernando M; Santos, Ana B; Costa, Marcos H; Ladle, Richard J

2016-08-01

Sustainable intensification of agriculture is one of the main strategies to provide global food security. However, its implementation raises enormous political, technological, and social challenges. Meeting these challenges will require, among other things, accurate information on the spatial and temporal patterns of agricultural land use and yield. Here, we investigate historical patterns of agricultural land use (1940-2012) and productivity (1990-2012) in Brazil using a new high-resolution (approximately 1 km(2) ) spatially explicit reconstruction. Although Brazilian agriculture has been historically known for its extensification over natural vegetation (Amazon and Cerrado), data from recent years indicate that extensification has slowed down and was replaced by a strong trend of intensification. Our results provide the first comprehensive historical overview of agricultural land use and productivity in Brazil, providing clear insights to guide future territorial planning, sustainable agriculture, policy, and decision-making. © 2016 John Wiley & Sons Ltd.

Phosphors for X-ray intensification screens

International Nuclear Information System (INIS)

Rebatin, J.G.

1980-01-01

An improved rare earth oxyhalide phosphor for x-ray intensification screens is described. The phosphors, of formula LnOX.T where Ln = La or Gd, X = Cl or Br and T = Tm or Tb, are mixed with a small amount of a trivalent antimony compound. The addition of antimony overcomes ageing due to attack by atmospheric moisture and renders the phosphor freeflowing so that dispersions can be readily made. Preferably the phosphor is washed with an aqueous solution of the antimony compound and the compound is the fluoride, chloride or butoxide, or potassium antimony tartrate. (U.K.)

Elevage intensif du loup Dicentrarchus labrax

OpenAIRE

Coves, Denis; Gasset, Eric

1993-01-01

Cet article fait le point sue les coûts de production directs relatifs à différentes méthodes d'élevage intensif du loup (Dicentrarchus labrax). Il s'appuie sur des résultats zootechniques obtenus dans l'unité de démonstration à grande échelle de notre laboratoire. Par rapport à un système de production en circuit ouvert, le recyclage de l'eau permet de diviser par 2.2 les charges directes de production. Si les proies vivantes sont précédemment remplacées par une microparticule efficace, ces ...

Analysis of the Arctic system for freshwater cycle intensification: Observations and expectations

Science.gov (United States)

Rawlins, M.A.; Steele, M.; Holland, M.M.; Adam, J.C.; Cherry, J.E.; Francis, J.A.; Groisman, P.Y.; Hinzman, L.D.; Huntington, T.G.; Kane, D.L.; Kimball, J.S.; Kwok, R.; Lammers, R.B.; Lee, C.M.; Lettenmaier, D.P.; McDonald, K.C.; Podest, E.; Pundsack, J.W.; Rudels, B.; Serreze, Mark C.; Shiklomanov, A.; Skagseth, O.; Troy, T.J.; Vorosmarty, C.J.; Wensnahan, M.; Wood, E.F.; Woodgate, R.; Yang, D.; Zhang, K.; Zhang, T.

2010-01-01

Hydrologic cycle intensification is an expected manifestation of a warming climate. Although positive trends in several global average quantities have been reported, no previous studies have documented broad intensification across elements of the Arctic freshwater cycle (FWC). In this study, the authors examine the character and quantitative significance of changes in annual precipitation, evapotranspiration, and river discharge across the terrestrial pan-Arctic over the past several decades from observations and a suite of coupled general circulation models (GCMs). Trends in freshwater flux and storage derived from observations across the Arctic Ocean and surrounding seas are also described. With few exceptions, precipitation, evapotranspiration, and river discharge fluxes from observations and the GCMs exhibit positive trends. Significant positive trends above the 90% confidence level, however, are not present for all of the observations. Greater confidence in the GCM trends arises through lower interannual variability relative to trend magnitude. Put another way, intrinsic variability in the observations tends to limit confidence in trend robustness. Ocean fluxes are less certain, primarily because of the lack of long-term observations. Where available, salinity and volume flux data suggest some decrease in saltwater inflow to the Barents Sea (i.e., a decrease in freshwater outflow) in recent decades. A decline in freshwater storage across the central Arctic Ocean and suggestions that large-scale circulation plays a dominant role in freshwater trends raise questions as to whether Arctic Ocean freshwater flows are intensifying. Although oceanic fluxes of freshwater are highly variable and consistent trends are difficult to verify, the other components of the Arctic FWC do show consistent positive trends over recent decades. The broad-scale increases provide evidence that the Arctic FWC is experiencing intensification. Efforts that aim to develop an adequate

The Impacts of Dry Dynamic Cores on Asymmetric Hurricane Intensification

Science.gov (United States)

Guimond, Stephen R.; Reisner, Jon M.; Marras, Simone; Giraldo, Francis X.

2016-01-01

The fundamental pathways for tropical cyclone (TC) intensification are explored by considering axisymmetric and asymmetric impulsive thermal perturbations to balanced, TC-like vortices using the dynamic cores of three different nonlinear numerical models. Attempts at reproducing the results of previous work, which used the community WRF Model, revealed a discrepancy with the impacts of purely asymmetric thermal forcing. The current study finds that thermal asymmetries can have an important, largely positive role on the vortex intensification, whereas other studies find that asymmetric impacts are negligible. Analysis of the spectral energetics of each numerical model indicates that the vortex response to asymmetric thermal perturbations is significantly damped in WRF relative to the other models. Spectral kinetic energy budgets show that this anomalous damping is primarily due to the increased removal of kinetic energy from the vertical divergence of the vertical pressure flux, which is related to the flux of inertia-gravity wave energy. The increased kinetic energy in the other two models is shown to originate around the scales of the heating and propagate upscale with time from nonlinear effects. For very large thermal amplitudes (50 K), the anomalous removal of kinetic energy due to inertia-gravity wave activity is much smaller, resulting in good agreement between models. The results of this paper indicate that the numerical treatment of small-scale processes that project strongly onto inertia-gravity wave energy can lead to significant differences in asymmetric TC intensification. Sensitivity tests with different time integration schemes suggest that diffusion entering into the implicit solution procedure is partly responsible for the anomalous damping of energy.

Land-use intensification causes multitrophic homogenization of grassland communities.

Science.gov (United States)

Gossner, Martin M; Lewinsohn, Thomas M; Kahl, Tiemo; Grassein, Fabrice; Boch, Steffen; Prati, Daniel; Birkhofer, Klaus; Renner, Swen C; Sikorski, Johannes; Wubet, Tesfaye; Arndt, Hartmut; Baumgartner, Vanessa; Blaser, Stefan; Blüthgen, Nico; Börschig, Carmen; Buscot, Francois; Diekötter, Tim; Jorge, Leonardo Ré; Jung, Kirsten; Keyel, Alexander C; Klein, Alexandra-Maria; Klemmer, Sandra; Krauss, Jochen; Lange, Markus; Müller, Jörg; Overmann, Jörg; Pašalić, Esther; Penone, Caterina; Perović, David J; Purschke, Oliver; Schall, Peter; Socher, Stephanie A; Sonnemann, Ilja; Tschapka, Marco; Tscharntke, Teja; Türke, Manfred; Venter, Paul Christiaan; Weiner, Christiane N; Werner, Michael; Wolters, Volkmar; Wurst, Susanne; Westphal, Catrin; Fischer, Markus; Weisser, Wolfgang W; Allan, Eric

2016-12-08

Land-use intensification is a major driver of biodiversity loss. Alongside reductions in local species diversity, biotic homogenization at larger spatial scales is of great concern for conservation. Biotic homogenization means a decrease in β-diversity (the compositional dissimilarity between sites). Most studies have investigated losses in local (α)-diversity and neglected biodiversity loss at larger spatial scales. Studies addressing β-diversity have focused on single or a few organism groups (for example, ref. 4), and it is thus unknown whether land-use intensification homogenizes communities at different trophic levels, above- and belowground. Here we show that even moderate increases in local land-use intensity (LUI) cause biotic homogenization across microbial, plant and animal groups, both above- and belowground, and that this is largely independent of changes in α-diversity. We analysed a unique grassland biodiversity dataset, with abundances of more than 4,000 species belonging to 12 trophic groups. LUI, and, in particular, high mowing intensity, had consistent effects on β-diversity across groups, causing a homogenization of soil microbial, fungal pathogen, plant and arthropod communities. These effects were nonlinear and the strongest declines in β-diversity occurred in the transition from extensively managed to intermediate intensity grassland. LUI tended to reduce local α-diversity in aboveground groups, whereas the α-diversity increased in belowground groups. Correlations between the β-diversity of different groups, particularly between plants and their consumers, became weaker at high LUI. This suggests a loss of specialist species and is further evidence for biotic homogenization. The consistently negative effects of LUI on landscape-scale biodiversity underscore the high value of extensively managed grasslands for conserving multitrophic biodiversity and ecosystem service provision. Indeed, biotic homogenization rather than local diversity

Intensification of grassland and forage use: driving forces and constraints

NARCIS (Netherlands)

Oenema, O.; Klein, de C.; Alfaro, M.

2014-01-01

The increasing demand for safe and nutritional dairy and beef products in a globalising world, together with the needs to increase resource use efficiency and to protect biodiversity, provide strong incentives for intensification of grassland and forage use. This paper addresses the question: 'Does

Food security and sustainable intensification.

Science.gov (United States)

Godfray, H Charles J; Garnett, Tara

2014-04-05

The coming decades are likely to see increasing pressures on the global food system, both on the demand side from increasing population and per capita consumption, and on the supply side from greater competition for inputs and from climate change. This paper argues that the magnitude of the challenge is such that action is needed throughout the food system, on moderating demand, reducing waste, improving governance and producing more food. It discusses in detail the last component, arguing that more food should be produced using sustainable intensification (SI) strategies, and explores the rationale behind, and meaning of, this term. It also investigates how SI may interact with other food policy agendas, in particular, land use and biodiversity, animal welfare and human nutrition.

Therapeutic Inertia and Treatment Intensification.

Science.gov (United States)

Josiah Willock, Robina; Miller, Joseph B; Mohyi, Michelle; Abuzaanona, Ahmed; Muminovic, Meri; Levy, Phillip D

2018-01-29

This review aims to emphasize how therapeutic inertia, the failure of clinicians to intensify treatment when blood pressure rises or remains above therapeutic goals, contributes to suboptimal blood pressure control in hypertensive populations. Studies reveal that the therapeutic inertia is quite common and contributes to suboptimal blood pressure control. Quality improvement programs and standardized approaches to support antihypertensive treatment intensification are ways to combat therapeutic inertia. Furthermore, programs that utilize non-physician medical professionals such as pharmacists and nurses demonstrate promise in mitigating the effects of this important problem. Therapeutic inertia impedes antihypertensive management and requires a broad effort to reduce its effects. There is an ongoing need for renewed focus and research in this area to improve hypertension control.

Rapid and reliable detection and identification of GM events using multiplex PCR coupled with oligonucleotide microarray.

Science.gov (United States)

Xu, Xiaodan; Li, Yingcong; Zhao, Heng; Wen, Si-yuan; Wang, Sheng-qi; Huang, Jian; Huang, Kun-lun; Luo, Yun-bo

2005-05-18

To devise a rapid and reliable method for the detection and identification of genetically modified (GM) events, we developed a multiplex polymerase chain reaction (PCR) coupled with a DNA microarray system simultaneously aiming at many targets in a single reaction. The system included probes for screening gene, species reference gene, specific gene, construct-specific gene, event-specific gene, and internal and negative control genes. 18S rRNA was combined with species reference genes as internal controls to assess the efficiency of all reactions and to eliminate false negatives. Two sets of the multiplex PCR system were used to amplify four and five targets, respectively. Eight different structure genes could be detected and identified simultaneously for Roundup Ready soybean in a single microarray. The microarray specificity was validated by its ability to discriminate two GM maizes Bt176 and Bt11. The advantages of this method are its high specificity and greatly reduced false-positives and -negatives. The multiplex PCR coupled with microarray technology presented here is a rapid and reliable tool for the simultaneous detection of GM organism ingredients.

Nested archetypes of vulnerability in African drylands: where lies potential for sustainable agricultural intensification?

Science.gov (United States)

Sietz, D.; Ordoñez, J. C.; Kok, M. T. J.; Janssen, P.; Hilderink, H. B. M.; Tittonell, P.; Van Dijk, H.

2017-09-01

Food production is key to achieving food security in the drylands of sub-Saharan Africa. Since agricultural productivity is limited, however, due to inherent agro-ecological constraints and land degradation, sustainable agricultural intensification has been widely discussed as an opportunity for improving food security and reducing vulnerability. Yet vulnerability determinants are distributed heterogeneously in the drylands of sub-Saharan Africa and sustainable intensification cannot be achieved everywhere in cost-effective and efficient ways. To better understand the heterogeneity of farming systems’ vulnerability in order to support decision making at regional scales, we present archetypes, i.e. socio-ecological patterns, of farming systems’ vulnerability in the drylands of sub-Saharan Africa and reveal their nestedness. We quantitatively indicated the most relevant farming systems’ properties at a sub-national resolution. These factors included water availability, agro-ecological potential, erosion sensitivity, population pressure, urbanisation, remoteness, governance, income and undernourishment. Cluster analysis revealed eight broad archetypes of vulnerability across all drylands of sub-Saharan Africa. The broad archetype representing better governance and highest remoteness in extremely dry and resource-constrained regions encompassed the largest area share (19%), mainly indicated in western Africa. Moreover, six nested archetypes were identified within those regions with better agropotential and prevalent agricultural livelihoods. Among these patterns, the nested archetype depicting regions with highest erosion sensitivity, severe undernourishment and lower agropotential represented the largest population (30%) and area (28%) share, mainly found in the Sahel region. The nested archetype indicating medium undernourishment, better governance and lowest erosion sensitivity showed particular potential for sustainable agricultural intensification, mainly in

Energetic atomic and molecular ions of ionospheric origin observed in distant magnetotail flow-reversal events

Science.gov (United States)

Christon, S. P.; Gloeckler, G.; Williams, D. J.; Mukai, T.; Mcentire, R. W.; Jacquey, C.; Angelopoulos, V.; Lui, A. T. Y.; Kokubun, S.; Fairfield, D. H.

1994-01-01

Energetic atomic (O(+1) and N(+1)) and molecular (O2(+1), NO(+1), and N2(+1)) ions of ionospheric origin were observed in Earth's magnetotail at X approximately -146 R(sub E) during two plasma sheet sunward/tailward flow-reversal events measured by instruments on the GEOTAIL spacecraft. These events were associated with concurrent ground-measured geomagnetic disturbance intensification at auroral-and mid-latitudes (Kp = 7(-)). Energetic ions in the sunward-component and tailward flows were from both the solar wind and ionosphere. Plasma and energetic ions participated in the flows. During tailward flow, ionospheric origin ion abundance ratios at approximately 200-900 km/s in the rest frame were N(+1)/O(+1) = approximately 25-30% and ((O2(+1), NO(+1), and N2(+1))/O(+1) = approximately 1-2%. We argue that tailward flow most likely initiated approximately 80-100 R(sub E) tailward of Earth and molecular ions were in the plasma sheet prior to geomagnetic intensification onset.

Sustainable intensification in agricultural systems.

Science.gov (United States)

Pretty, Jules; Bharucha, Zareen Pervez

2014-12-01

Agricultural systems are amended ecosystems with a variety of properties. Modern agroecosystems have tended towards high through-flow systems, with energy supplied by fossil fuels directed out of the system (either deliberately for harvests or accidentally through side effects). In the coming decades, resource constraints over water, soil, biodiversity and land will affect agricultural systems. Sustainable agroecosystems are those tending to have a positive impact on natural, social and human capital, while unsustainable systems feed back to deplete these assets, leaving fewer for the future. Sustainable intensification (SI) is defined as a process or system where agricultural yields are increased without adverse environmental impact and without the conversion of additional non-agricultural land. The concept does not articulate or privilege any particular vision or method of agricultural production. Rather, it emphasizes ends rather than means, and does not pre-determine technologies, species mix or particular design components. The combination of the terms 'sustainable' and 'intensification' is an attempt to indicate that desirable outcomes around both more food and improved environmental goods and services could be achieved by a variety of means. Nonetheless, it remains controversial to some. This review analyses recent evidence of the impacts of SI in both developing and industrialized countries, and demonstrates that both yield and natural capital dividends can occur. The review begins with analysis of the emergence of combined agricultural-environmental systems, the environmental and social outcomes of recent agricultural revolutions, and analyses the challenges for food production this century as populations grow and consumption patterns change. Emergent criticisms are highlighted, and the positive impacts of SI on food outputs and renewable capital assets detailed. It concludes with observations on policies and incentives necessary for the wider adoption of

Effect of rosuvastatin intensification therapy on blood lipid metabolism, adipocytokines and plaque stability after PCI in ACS patients

Directory of Open Access Journals (Sweden)

Xiu-Quan Sun

2017-10-01

Full Text Available Objective: To explore the effect of rosuvastatin intensification therapy on blood lipid metabolism, adipocytokines and plaque stability after PCI in ACS patients. Methods: ACS patients who received PCI in the hospital between July 2015 and January 2017were reviewed and divided into the routine dose group (n=60 who received rosuvastatin routine dose therapy after PCI and the intensification therapy group (n=46 who received rosuvastatin intensification therapy after PCI. The differences in blood lipid metabolism, adipocytokines and plaque stability were compared between the two groups before and after treatment. Results: Before PCI, the differences in blood lipid metabolism, adipocytokines and plaque stability were not statistically significant between the two groups. 1 month after PCI, lipid metabolism indexes HDL-C and ApoA1 levels in peripheral blood of intensification therapy group were higher than those of routine dose group while LDL-C and ApoB levels were lower than those of routine dose group; adipocytokines APN and Leptin levels in serum were higher than those of routine dose group while Resistin level was lower than that of routine dose group; plaque stability- related indexes ICAM-1, MMP-1 and TIMP-1 levels were lower than those of routine dose group. Conclusion: Rosuvastatin intensification therapy after PCI could effectively regulate the lipid metabolism and increase the plaque stability in ACS patients.

Soil biota community structure and abundance under agricultural intensification and extensification

NARCIS (Netherlands)

Postma-Blaauw, M.B.; Goede, de R.G.M.; Bloem, J.; Faber, J.H.; Brussaard, L.

2010-01-01

Understanding the impacts of agricultural intensification and extensification on soil biota communities is useful in order to preserve and restore biological diversity in agricultural soils and enhance the role of soil biota in agroecosystem functioning. Over four consecutive years, we investigated

School Principals' Job Satisfaction: The Effects of Work Intensification

Science.gov (United States)

Wang, Fei; Pollock, Katina; Hauseman, Cameron

2018-01-01

This study examines principals' job satisfaction in relation to their work intensification. Frederick Herzberg's two-factor theory was used to shed light on how motivating and maintenance factors affect principals' job satisfaction. Logistic multiple regressions were used in the analysis of survey data that were collected from 2,701 elementary and…

Tradeoffs between income, biodiversity, and ecosystem functioning during tropical rainforest conversion and agroforestry intensification.

Science.gov (United States)

Steffan-Dewenter, Ingolf; Kessler, Michael; Barkmann, Jan; Bos, Merijn M; Buchori, Damayanti; Erasmi, Stefan; Faust, Heiko; Gerold, Gerhard; Glenk, Klaus; Gradstein, S Robbert; Guhardja, Edi; Harteveld, Marieke; Hertel, Dietrich; Höhn, Patrick; Kappas, Martin; Köhler, Stefan; Leuschner, Christoph; Maertens, Miet; Marggraf, Rainer; Migge-Kleian, Sonja; Mogea, Johanis; Pitopang, Ramadhaniel; Schaefer, Matthias; Schwarze, Stefan; Sporn, Simone G; Steingrebe, Andrea; Tjitrosoedirdjo, Sri S; Tjitrosoemito, Soekisman; Twele, André; Weber, Robert; Woltmann, Lars; Zeller, Manfred; Tscharntke, Teja

2007-03-20

Losses of biodiversity and ecosystem functioning due to rainforest destruction and agricultural intensification are prime concerns for science and society alike. Potentially, ecosystems show nonlinear responses to land-use intensification that would open management options with limited ecological losses but satisfying economic gains. However, multidisciplinary studies to quantify ecological losses and socioeconomic tradeoffs under different management options are rare. Here, we evaluate opposing land use strategies in cacao agroforestry in Sulawesi, Indonesia, by using data on species richness of nine plant and animal taxa, six related ecosystem functions, and on socioeconomic drivers of agroforestry expansion. Expansion of cacao cultivation by 230% in the last two decades was triggered not only by economic market mechanisms, but also by rarely considered cultural factors. Transformation from near-primary forest to agroforestry had little effect on overall species richness, but reduced plant biomass and carbon storage by approximately 75% and species richness of forest-using species by approximately 60%. In contrast, increased land use intensity in cacao agroforestry, coupled with a reduction in shade tree cover from 80% to 40%, caused only minor quantitative changes in biodiversity and maintained high levels of ecosystem functioning while doubling farmers' net income. However, unshaded systems further increased income by approximately 40%, implying that current economic incentives and cultural preferences for new intensification practices put shaded systems at risk. We conclude that low-shade agroforestry provides the best available compromise between economic forces and ecological needs. Certification schemes for shade-grown crops may provide a market-based mechanism to slow down current intensification trends.

Measuring the potential for sustainable intensification of aquaculture in Bangladesh using life cycle assessment.

Science.gov (United States)

Henriksson, Patrik John Gustav; Belton, Ben; Jahan, Khondker Murshed-E-; Rico, Andreu

2018-03-20

Food production is a major driver of global environmental change and the overshoot of planetary sustainability boundaries. Greater affluence in developing nations and human population growth are also increasing demand for all foods, and for animal proteins in particular. Consequently, a growing body of literature calls for the sustainable intensification of food production, broadly defined as "producing more using less". Most assessments of the potential for sustainable intensification rely on only one or two indicators, meaning that ecological trade-offs among impact categories that occur as production intensifies may remain unaccounted for. The present study addresses this limitation using life cycle assessment (LCA) to quantify six local and global environmental consequences of intensifying aquaculture production in Bangladesh. Production data are from a unique survey of 2,678 farms, and results show multidirectional associations between the intensification of aquaculture production and its environmental impacts. Intensification (measured in material and economic output per unit primary area farmed) is positively correlated with acidification, eutrophication, and ecotoxicological impacts in aquatic ecosystems; negatively correlated with freshwater consumption; and indifferent with regard to global warming and land occupation. As production intensifies, the geographical locations of greenhouse gas (GHG) emissions, acidifying emissions, freshwater consumption, and land occupation shift from the immediate vicinity of the farm to more geographically dispersed telecoupled locations across the globe. Simple changes in fish farming technology and management practices that could help make the global transition to more intensive forms of aquaculture be more sustainable are identified. Copyright © 2018 the Author(s). Published by PNAS.

Observations of rapid-fire event tremor at Lascar volcano, Chile

Directory of Open Access Journals (Sweden)

H. Rademacher

1996-06-01

Full Text Available During the Proyecto de Investigaciòn Sismològica de la Cordillera Occidental (PISCO '94 in the Atacama desert of Northern Chile, a continuously recording broadband seismic station was installed to the NW of the currently active volcano, Lascar. For the month of April, 1994, an additional network of three, short period, three-component stations was deployed around the volcano to help discriminate its seismic signals from other local seismicity. During the deployment, the volcanic activity at Lascar appeared to be limited mainly to the emission of steam and SO2. Tremor from Lascar is a random, «rapid-fire» series of events with a wide range of amplitudes and a quasi-fractal structure. The tremor is generated by an ensemble of independent elementary sources clustered in the volcanic edifice. In the short-term, the excitation of the sources fluctuates strongly, while the long-term power spectrum is very stationary.

Superiority of centralized procurement and its technical and economic analysis for nuclear power intensification construction

International Nuclear Information System (INIS)

Wang Feng

2010-01-01

The intensified management is the basic orientation for modernized enterprise group to improve efficiency and benefit. For most industrial enterprises, in the implementation of intensification management process, the centralized procurement is one of most efficient paths. At present most of the international's and domestic outstanding enterprises are studying and positively using this approach. This article indicated that the centralized procurement mode is inevitable during intensification construction process based on the theoretical analysis of the advantage of centralized procurement and the economic analysis of typical cases. (author)

Big agronomic data validates an oxymoron: Sustainable intensification under climate change

Science.gov (United States)

Crop science is increasingly embracing big data to reconcile the apparent rift between intensification of food production and sustainability of a steadily stressed production base. A strategy based on long-term agroecosystem research and modeling simulation of crops, crop rotations and cropping sys...

Agricultural intensification exacerbates spillover effects on soil biogeochemistry in adjacent forest remnants.

Directory of Open Access Journals (Sweden)

Raphael K Didham

Full Text Available Land-use intensification is a central element in proposed strategies to address global food security. One rationale for accepting the negative consequences of land-use intensification for farmland biodiversity is that it could 'spare' further expansion of agriculture into remaining natural habitats. However, in many regions of the world the only natural habitats that can be spared are fragments within landscapes dominated by agriculture. Therefore, land-sparing arguments hinge on land-use intensification having low spillover effects into adjacent protected areas, otherwise net conservation gains will diminish with increasing intensification. We test, for the first time, whether the degree of spillover from farmland into adjacent natural habitats scales in magnitude with increasing land-use intensity. We identified a continuous land-use intensity gradient across pastoral farming systems in New Zealand (based on 13 components of farmer input and soil biogeochemistry variables, and measured cumulative off-site spillover effects of fertilisers and livestock on soil biogeochemistry in 21 adjacent forest remnants. Ten of 11 measured soil properties differed significantly between remnants and intact-forest reference sites, for both fenced and unfenced remnants, at both edge and interior. For seven variables, the magnitude of effects scaled significantly with magnitude of surrounding land-use intensity, through complex interactions with fencing and edge effects. In particular, total C, total N, δ15N, total P and heavy-metal contaminants of phosphate fertilizers (Cd and U increased significantly within remnants in response to increasing land-use intensity, and these effects were exacerbated in unfenced relative to fenced remnants. This suggests movement of livestock into surrounding natural habitats is a significant component of agricultural spillover, but pervasive changes in soil biogeochemistry still occur through nutrient spillover channels alone

The role of mid-level vortex in the intensification and weakening of ...

Indian Academy of Sciences (India)

Govindan Kutty

2017-10-06

Oct 6, 2017 ... the importance of such vortex developments in the intensification of tropical cyclone. The genesis ... ing a thermodynamically favourable environment to facilitate .... zontal extension, intensity and organization of PV at both the ...

The Use of Pre-Storm Boundary-Layer Baroclinicity in Determining and Operationally Implementing the Atlantic Surface Cyclone Intensification Index

Science.gov (United States)

Cione, Joseph; Pietrafes, Leonard J.

The lateral motion of the Gulf Stream off the eastern seaboard of the United States during the winter season can act to dramatically enhance the low-level baroclinicity within the coastal zone during periods of offshore cold advection. The ralative close proximity of the Gulf Stream current off the mid-Atlantic coast can result in the rapid and intense destabilization of the marine atmospheric boundary layer directly above and shoreward of the Gulf Stream within this region. This airmass modification period often precedes either wintertime coastal cyclogenesis or the cyclonic re-development of existing mid-latitude cyclones. A climatological study investigating the relationship between the severity of the pre-storm, cold advection period and subsequent cyclogenic intensification was undertaken by Cione et al. in 1993. Findings from this study illustrate that the thermal structure of the continental airmass as well as the position of the Gulf Stream front relative to land during the pre-storm period (i.e., 24-48 h prior to the initial cyclonic intensification) are linked to the observed rate of surface cyclonic deepening for storms that either advected into or initially developed within the Carolina-southeast Virginia offshore coastal zone. It is a major objective of this research to test the potential operational utility of this pre-storm low level baroclinic linkage to subsequent cyclogenesis in an actual National Weather Service (NWS) coastal winter storm forecast setting.The ability to produce coastal surface cyclone intensity forecasts recently became available to North Carolina State University researchers and NWS forecasters. This statistical forecast guidance utilizes regression relationships derived from a nine-season (January 1982-April 1990), 116-storm study conducted previously. During the period between February 1994 and February 1996, the Atlantic Surface Cyclone Intensification Index (ASCII) was successfully implemented in an operational setting by

Evaluating strategies for sustainable intensification of US agriculture through the Long-Term Agroecosystem Research network

Science.gov (United States)

Spiegal, S.; Bestelmeyer, B. T.; Archer, D. W.; Augustine, D. J.; Boughton, E. H.; Boughton, R. K.; Cavigelli, M. A.; Clark, P. E.; Derner, J. D.; Duncan, E. W.; Hapeman, C. J.; Harmel, R. D.; Heilman, P.; Holly, M. A.; Huggins, D. R.; King, K.; Kleinman, P. J. A.; Liebig, M. A.; Locke, M. A.; McCarty, G. W.; Millar, N.; Mirsky, S. B.; Moorman, T. B.; Pierson, F. B.; Rigby, J. R.; Robertson, G. P.; Steiner, J. L.; Strickland, T. C.; Swain, H. M.; Wienhold, B. J.; Wulfhorst, J. D.; Yost, M. A.; Walthall, C. L.

2018-03-01

Sustainable intensification is an emerging model for agriculture designed to reconcile accelerating global demand for agricultural products with long-term environmental stewardship. Defined here as increasing agricultural production while maintaining or improving environmental quality, sustainable intensification hinges upon decision-making by agricultural producers, consumers, and policy-makers. The Long-Term Agroecosystem Research (LTAR) network was established to inform these decisions. Here we introduce the LTAR Common Experiment, through which scientists and partnering producers in US croplands, rangelands, and pasturelands are conducting 21 independent but coordinated experiments. Each local effort compares the outcomes of a predominant, conventional production system in the region (‘business as usual’) with a system hypothesized to advance sustainable intensification (‘aspirational’). Following the logic of a conceptual model of interactions between agriculture, economics, society, and the environment, we identified commonalities among the 21 experiments in terms of (a) concerns about business-as-usual production, (b) ‘aspirational outcomes’ motivating research into alternatives, (c) strategies for achieving the outcomes, (d) practices that support the strategies, and (e) relationships between practice outreach and adoption. Network-wide, concerns about business as usual include the costs of inputs, opportunities lost to uniform management approaches, and vulnerability to accelerating environmental changes. Motivated by environmental, economic, and societal outcomes, scientists and partnering producers are investigating 15 practices in aspirational treatments to sustainably intensify agriculture, from crop diversification to ecological restoration. Collectively, the aspirational treatments reveal four general strategies for sustainable intensification: (1) reducing reliance on inputs through ecological intensification, (2) diversifying management

Winners and losers of national and global efforts to reconcile agricultural intensification and biodiversity conservation.

Science.gov (United States)

Egli, Lukas; Meyer, Carsten; Scherber, Christoph; Kreft, Holger; Tscharntke, Teja

2018-05-01

Closing yield gaps within existing croplands, and thereby avoiding further habitat conversions, is a prominently and controversially discussed strategy to meet the rising demand for agricultural products, while minimizing biodiversity impacts. The agricultural intensification associated with such a strategy poses additional threats to biodiversity within agricultural landscapes. The uneven spatial distribution of both yield gaps and biodiversity provides opportunities for reconciling agricultural intensification and biodiversity conservation through spatially optimized intensification. Here, we integrate distribution and habitat information for almost 20,000 vertebrate species with land-cover and land-use datasets. We estimate that projected agricultural intensification between 2000 and 2040 would reduce the global biodiversity value of agricultural lands by 11%, relative to 2000. Contrasting these projections with spatial land-use optimization scenarios reveals that 88% of projected biodiversity loss could be avoided through globally coordinated land-use planning, implying huge efficiency gains through international cooperation. However, global-scale optimization also implies a highly uneven distribution of costs and benefits, resulting in distinct "winners and losers" in terms of national economic development, food security, food sovereignty or conservation. Given conflicting national interests and lacking effective governance mechanisms to guarantee equitable compensation of losers, multinational land-use optimization seems politically unlikely. In turn, 61% of projected biodiversity loss could be avoided through nationally focused optimization, and 33% through optimization within just 10 countries. Targeted efforts to improve the capacity for integrated land-use planning for sustainable intensification especially in these countries, including the strengthening of institutions that can arbitrate subnational land-use conflicts, may offer an effective, yet

Science, practice and the System of Rice Intensification in Indian agriculture

NARCIS (Netherlands)

Glover, D.

2011-01-01

The System of Rice Intensification (SRI) is claimed to be a novel approach to rice cultivation that is both more productive and more sustainable than conventional methods. Such claims have been challenged or dismissed by many rice scientists, however. Despite the lack of clear and unequivocal

High intensification screen-film systems in thorax radiography: a clinical comparison

International Nuclear Information System (INIS)

Schaefer, C.B.; Sokiranski, R.; Claussen, C.D.

1995-01-01

Objective: The quality of chest images was evaluated for a conventional screen-film system, a new asymmetric screen-film system, and a new uv screen-film system. Materials and Methods: 138 Chest radiographs (69 p.a., 69 lateral) obtained with three different high intensification screen-film combinations were compared. Film density and film contrast were measured. Three readers graded the image quality according to 16 criteria. Results: The asymmetric film-screen combination Insight HC showed the lowest film contrast, the best exposure range, and a elevated film density in the mediastinal area. The asymmetric screen-film system was ranked by all three observers as being substantially better in image quality. Conclusion: Compared to conventional screen-film systems, the new screen-film systems can improve the image quality of chest radiographs. Therefore, the new high intensification screen-film combinations can be used as a low cost alternative to the Amber technique and digital radiography. (orig.) [de

Validated Competing Event Model for the Stage I-II Endometrial Cancer Population

Energy Technology Data Exchange (ETDEWEB)

Carmona, Ruben; Gulaya, Sachin; Murphy, James D. [Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, California (United States); Rose, Brent S. [Harvard Radiation Oncology Program, Harvard Medical School, Boston, Massachusetts (United States); Wu, John; Noticewala, Sonal [Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, California (United States); McHale, Michael T. [Department of Reproductive Medicine, Division of Gynecologic Oncology, University of California San Diego, La Jolla, California (United States); Yashar, Catheryn M. [Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, California (United States); Vaida, Florin [Department of Family and Preventive Medicine, Biostatistics and Bioinformatics, University of California San Diego Medical Center, San Diego, California (United States); Mell, Loren K., E-mail: lmell@ucsd.edu [Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, California (United States)

2014-07-15

Purpose/Objectives(s): Early-stage endometrial cancer patients are at higher risk of noncancer mortality than of cancer mortality. Competing event models incorporating comorbidity could help identify women most likely to benefit from treatment intensification. Methods and Materials: 67,397 women with stage I-II endometrioid adenocarcinoma after total hysterectomy diagnosed from 1988 to 2009 were identified in Surveillance, Epidemiology, and End Results (SEER) and linked SEER-Medicare databases. Using demographic and clinical information, including comorbidity, we sought to develop and validate a risk score to predict the incidence of competing mortality. Results: In the validation cohort, increasing competing mortality risk score was associated with increased risk of noncancer mortality (subdistribution hazard ratio [SDHR], 1.92; 95% confidence interval [CI], 1.60-2.30) and decreased risk of endometrial cancer mortality (SDHR, 0.61; 95% CI, 0.55-0.78). Controlling for other variables, Charlson Comorbidity Index (CCI) = 1 (SDHR, 1.62; 95% CI, 1.45-1.82) and CCI >1 (SDHR, 3.31; 95% CI, 2.74-4.01) were associated with increased risk of noncancer mortality. The 10-year cumulative incidences of competing mortality within low-, medium-, and high-risk strata were 27.3% (95% CI, 25.2%-29.4%), 34.6% (95% CI, 32.5%-36.7%), and 50.3% (95% CI, 48.2%-52.6%), respectively. With increasing competing mortality risk score, we observed a significant decline in omega (ω), indicating a diminishing likelihood of benefit from treatment intensification. Conclusion: Comorbidity and other factors influence the risk of competing mortality among patients with early-stage endometrial cancer. Competing event models could improve our ability to identify patients likely to benefit from treatment intensification.

Validated Competing Event Model for the Stage I-II Endometrial Cancer Population

International Nuclear Information System (INIS)

Carmona, Ruben; Gulaya, Sachin; Murphy, James D.; Rose, Brent S.; Wu, John; Noticewala, Sonal; McHale, Michael T.; Yashar, Catheryn M.; Vaida, Florin; Mell, Loren K.

2014-01-01

Purpose/Objectives(s): Early-stage endometrial cancer patients are at higher risk of noncancer mortality than of cancer mortality. Competing event models incorporating comorbidity could help identify women most likely to benefit from treatment intensification. Methods and Materials: 67,397 women with stage I-II endometrioid adenocarcinoma after total hysterectomy diagnosed from 1988 to 2009 were identified in Surveillance, Epidemiology, and End Results (SEER) and linked SEER-Medicare databases. Using demographic and clinical information, including comorbidity, we sought to develop and validate a risk score to predict the incidence of competing mortality. Results: In the validation cohort, increasing competing mortality risk score was associated with increased risk of noncancer mortality (subdistribution hazard ratio [SDHR], 1.92; 95% confidence interval [CI], 1.60-2.30) and decreased risk of endometrial cancer mortality (SDHR, 0.61; 95% CI, 0.55-0.78). Controlling for other variables, Charlson Comorbidity Index (CCI) = 1 (SDHR, 1.62; 95% CI, 1.45-1.82) and CCI >1 (SDHR, 3.31; 95% CI, 2.74-4.01) were associated with increased risk of noncancer mortality. The 10-year cumulative incidences of competing mortality within low-, medium-, and high-risk strata were 27.3% (95% CI, 25.2%-29.4%), 34.6% (95% CI, 32.5%-36.7%), and 50.3% (95% CI, 48.2%-52.6%), respectively. With increasing competing mortality risk score, we observed a significant decline in omega (ω), indicating a diminishing likelihood of benefit from treatment intensification. Conclusion: Comorbidity and other factors influence the risk of competing mortality among patients with early-stage endometrial cancer. Competing event models could improve our ability to identify patients likely to benefit from treatment intensification

LivestockPlus — The sustainable intensification of forage-based agricultural systems to improve livelihoods and ecosystem services in the tropics

Directory of Open Access Journals (Sweden)

I. Rao

2015-05-01

Full Text Available As global demand for livestock products (such as meat, milk and eggs is expected to double by 2050, necessary increases to future production must be reconciled with negative environmental impacts that livestock cause. This paper describes the LivestockPlus concept and demonstrates how the sowing of improved forages can lead to the sustainable intensification of mixed crop-forage-livestock-tree systems in the tropics by producing multiple social, economic and environmental benefits. Sustainable intensification not only improves the productivity of tropical forage-based systems but also reduces the ecological footprint of livestock production and generates a diversity of ecosystem services (ES such as improved soil quality and reduced erosion, sedimentation and greenhouse gas (GHG emissions. Integrating improved grass and legume forages into mixed production systems (crop-livestock, tree-livestock, crop-tree-livestock can restore degraded lands and enhance system resilience to drought and waterlogging associated with climate change. When properly managed tropical forages accumulate large amounts of carbon in soil, fix atmospheric nitrogen (legumes, inhibit nitrification in soil and reduce nitrous oxide emissions (grasses, and reduce GHG emissions per unit livestock product. The LivestockPlus concept is defined as the sustainable intensification of forage-based systems, which is based on 3 interrelated intensification processes: genetic intensification - the development and use of superior grass and legume cultivars for increased livestock productivity; ecological intensification - the development and application of improved farm and natural resource management practices; and socio-economic intensification - the improvement of local and national institutions and policies, which enable refinements of technologies and support their enduring use. Increases in livestock productivity will require coordinated efforts to develop supportive government, non

The dream-lag effect: selective processing of personally significant events during Rapid Eye Movement sleep, but not during Slow Wave Sleep

OpenAIRE

van Rijn, E.; Eichenlaub, J.-B.; Lewis, Penelope A.; Walker, M.P.; Gaskell, M.G.; Malinowski, J.E.; Blagrove, M.

2015-01-01

Incorporation of details from waking life events into Rapid Eye Movement (REM) sleep dreams has been found to be highest on the night after, and then 5-7 nights after events (termed, respectively, the day-residue and dream-lag effects). In experiment 1, 44 participants kept a daily log for 10. days, reporting major daily activities (MDAs), personally significant events (PSEs), and major concerns (MCs). Dream reports were collected from REM and Slow Wave Sleep (SWS) in the laboratory, or from ...

Adverse effectsof agricultaral intensification and climate change on breeding habitat quality of Blacktailed Godwits Limosa l. limosa in the Netherlands

NARCIS (Netherlands)

Kleijn, D.; Schekkerman, H.; Dimmers, W.J.; Kats, van R.J.M.; Melman, T.C.P.; Teunissen, W.A.

2010-01-01

Agricultural intensification is one of the main drivers of farmland bird declines, but effects on birds may be confounded with those of climate change. Here we examine the effects of intensification and climate change on a grassland breeding wader, the Black-tailed Godwit Limosa l. limosa, in the

Spider fauna of semiarid eastern Colorado agroecosystems: diversity, abundance, and effects of crop intensification.

Science.gov (United States)

Kerzicnik, Lauren M; Peairs, Frank B; Cushing, Paula E; Draney, Michael L; Merrill, Scott C

2013-02-01

Spiders are critical predators in agroecosystems. Crop management practices can influence predator density and diversity, which, in turn, can influence pest management strategies. Crop intensification is a sustainable agricultural technique that can enhance crop production although optimizing soil moisture. To date, there is no information on how crop intensification affects natural enemy populations, particularly spiders. This study had two objectives: to characterize the abundance and diversity of spiders in eastern Colorado agroecosystems, and to test the hypothesis that spider diversity and density would be higher in wheat (Triticum aestivum L.) in crop-intensified rotations compared with wheat in conventional rotations. We collected spiders through pitfall, vacuum, and lookdown sampling from 2002 to 2007 to test these objectives. Over 11,000 spiders in 19 families from 119 species were captured from all sampling techniques. Interestingly, the hunting spider guild represented 89% of the spider fauna captured from all sites with the families Gnaphosidae and Lycosidae representing 75% of these spiders. Compared with European agroecosystems, these agroecosystems had greater diversity, which can be beneficial for the biological control of pests. Overall, spider densities were low in these semiarid cropping systems, and crop intensification effects on spider densities were not evident at this scale.

A semi-automated method for rapid detection of ripple events on interictal voltage discharges in the scalp electroencephalogram.

Science.gov (United States)

Chu, Catherine J; Chan, Arthur; Song, Dan; Staley, Kevin J; Stufflebeam, Steven M; Kramer, Mark A

2017-02-01

High frequency oscillations are emerging as a clinically important indicator of epileptic networks. However, manual detection of these high frequency oscillations is difficult, time consuming, and subjective, especially in the scalp EEG, thus hindering further clinical exploration and application. Semi-automated detection methods augment manual detection by reducing inspection to a subset of time intervals. We propose a new method to detect high frequency oscillations that co-occur with interictal epileptiform discharges. The new method proceeds in two steps. The first step identifies candidate time intervals during which high frequency activity is increased. The second step computes a set of seven features for each candidate interval. These features require that the candidate event contain a high frequency oscillation approximately sinusoidal in shape, with at least three cycles, that co-occurs with a large amplitude discharge. Candidate events that satisfy these features are stored for validation through visual analysis. We evaluate the detector performance in simulation and on ten examples of scalp EEG data, and show that the proposed method successfully detects spike-ripple events, with high positive predictive value, low false positive rate, and high intra-rater reliability. The proposed method is less sensitive than the existing method of visual inspection, but much faster and much more reliable. Accurate and rapid detection of high frequency activity increases the clinical viability of this rhythmic biomarker of epilepsy. The proposed spike-ripple detector rapidly identifies candidate spike-ripple events, thus making clinical analysis of prolonged, multielectrode scalp EEG recordings tractable. Copyright © 2016 Elsevier B.V. All rights reserved.

Intensification agricole en région sahélo-soudanienne. 2. Productivité et risques économiques

Directory of Open Access Journals (Sweden)

Abdoulaye Dieng

1997-01-01

Full Text Available Intensification of farming in the Sahelian-Sudanese region. 2. Productivity and economic risks.his second part concerns the analysis of land productivity and labour results within a traditional farming system and two improved systems experimented on a site in the center-west part of the Senegalese groundnut basin. Intensified farming systems associate farming and livestock and use motorized or draft cultivation (oxen as means of mechanization. Results show that intensification systematically increases crop yields and gives rise to larger amounts of by-products fitting well for use as animal feed. Furthermore, yields stabilize with soil fertility improvement. The economic risk linked to intensification strongly depends on the climatic context. A 400 mm annual rainfall appears as a threshold to insure a net increase of land and labour productivity, justifying an intensification operation that combines plowing, liming material, organic and minerai fertilizer applications. In the climatic risk zone like that where the experimentation took place, the diversification of farming activity increases and stabilizes income. Therefore, productions as cassava or bissap and the integration of a perennial forage crop offer interesting development perspectives. The constraints limiting the adoption of intensified and diversified farming systems are linked to market conditions, time-labour feasibility, soil fertility management and institutional context. To minimize the risks, tactical adjustments are also analyzed.

Aquaculture innovation system analysis of transition to sustainable intensification in shrimp farming

NARCIS (Netherlands)

Joffre, Olivier M.; Klerkx, Laurens; Khoa, Tran N.D.

2018-01-01

The shrimp sector has been one of the fastest growing agri-food systems in the last decades, but its growth has entailed negative social and environmental impacts. Sustainable intensification will require innovation in multiple elements of the shrimp production system and its value chain. We use

Quantifying the Precipitation Loss of Radiation Belt Electrons during a Rapid Dropout Event

Science.gov (United States)

Pham, K. H.; Tu, W.; Xiang, Z.

2017-12-01

Relativistic electron flux in the radiation belt can drop by orders of magnitude within the timespan of hours. In this study, we used the drift-diffusion model that includes azimuthal drift and pitch angle diffusion of electrons to simulate low-altitude electron distribution observed by POES/MetOp satellites for rapid radiation belt electron dropout event occurring on May 1, 2013. The event shows fast dropout of MeV energy electrons at L>4 over a few hours, observed by the Van Allen Probes mission. By simulating the electron distributions observed by multiple POES satellites, we resolve the precipitation loss with both high spatial and temporal resolution and a range of energies. We estimate the pitch angle diffusion coefficients as a function of energy, pitch angle, and L-shell, and calculate corresponding electron lifetimes during the event. The simulation results show fast electron precipitation loss at L>4 during the electron dropout, with estimated electron lifetimes on the order of half an hour for MeV energies. The electron loss rate show strong energy dependence with faster loss at higher energies, which suggest that this dropout event is dominated by quick and localized scattering process that prefers higher energy electrons. The estimated pitch angle diffusion rates from the model are then compared with in situ wave measurements from Van Allen Probes to uncover the underlying wave-particle-interaction mechanisms that are responsible for the fast electron precipitation. Comparing the resolved precipitation loss with the observed electron dropouts at high altitudes, our results will suggest the relative role of electron precipitation loss and outward radial diffusion to the radiation belt dropouts during storm and non-storm times, in addition to its energy and L dependence.

Adverse effects of agricultural intensification and climate change on breeding habitat quality of Blacktailed Godwits Limosa l. limosa in the Netherlands

NARCIS (Netherlands)

Kleijn, D.; Schekkerman, H.; Dimmers, W.J.; Van Kats, R.J.M.; Melman, D.; Teunissen, W.A.

2010-01-01

Agricultural intensification is one of the main drivers of farmland bird declines, but effects on birds may be confounded with those of climate change. Here we examine the effects of intensification and climate change on a grassland breeding wader, the Black-tailed Godwit Limosa l. limosa, in the

New Ultrasonic Controller and Characterization System for Low Temperature Drying Process Intensification

Science.gov (United States)

Andrés, R. R.; Blanco, A.; Acosta, V. M.; Riera, E.; Martínez, I.; Pinto, A.

Process intensification constitutes a high interesting and promising industrial area. It aims to modify conventional processes or develop new technologies in order to reduce energy needs, increase yields and improve product quality. It has been demonstrated by this research group (CSIC) that power ultrasound have a great potential in food drying processes. The effects associated with the application of power ultrasound can enhance heat and mass transfer and may constitute a way for process intensification. The objective of this work has been the design and development of a new ultrasonic system for the power characterization of piezoelectric plate-transducers, as excitation, monitoring, analysis, control and characterization of their nonlinear response. For this purpose, the system proposes a new, efficient and economic approach that separates the effect of different parameters of the process like excitation, medium and transducer parameters and variables (voltage, current, frequency, impedance, vibration velocity, acoustic pressure and temperature) by observing the electrical, mechanical, acoustical and thermal behavior, and controlling the vibrational state.

A process synthesis-intensification framework for the development of sustainable membrane-based operations

DEFF Research Database (Denmark)

Babi, Deenesh Kavi; Lutze, Philip; Woodley, John

2014-01-01

In this paper a multi-level, multi-scale framework for process synthesis-intensification that aims to make the process more sustainable than a base-case, which may represent a new process or an existing process, is presented. At the first level (operation-scale) a conceptual base case design...... of extension of the combined intensification-synthesis method and its application to generate membrane-based operations. Also, application of the framework is illustrated through a case study involving the production of methyl acetate where membrane-based intensified operations play a major role in determining...... is synthesized through the sequencing of unit operations and subsequently analyzed for identifying process hot-spots using economic, life cycle and sustainability metrics. These hot-spots are limitations/bottlenecks associated with tasks that may be targeted for overall process improvement. At the second level...

Neoteric Media as Tools for Process Intensification

Science.gov (United States)

Beh, C. C.; Mammucari, R.; Foster, N. R.

2017-06-01

Process intensification (PI) is a commonly used term in the chemical processing industry. When the concept of PI was first introduced in the late 1970s within the Imperial Chemical Industries (ICI) company, the main impetus was to reduce the processing cost without impairing the production rate. Neoteric media present as alternatives in chemical processing include gas-expanded liquids, ionic liquids, subcritical water, and combination of gas-expanded liquids and ionic liquids. The applications of neoteric media include particle engineering for improved bioavailability, controlled release of therapeutic implants, pharmaceutical formulations, extraction of natural products, nano-carriers for drug delivery, sterilisation of implants, and chemical reactions. This paper provides an overview of the use of these neoteric media.

Intensification of esterification of acids for synthesis of biodiesel using acoustic and hydrodynamic cavitation.

Science.gov (United States)

Kelkar, Mandar A; Gogate, Parag R; Pandit, Aniruddha B

2008-03-01

Cavitation results in conditions of turbulence and liquid circulation in the reactor which can aid in eliminating mass transfer resistances. The present work illustrates the use of cavitation for intensification of biodiesel synthesis (esterification) reaction, which is mass transfer limited reaction considering the immiscible nature of the reactants, i.e., fatty acids and alcohol. Esterification of fatty acid (FA) odour cut (C(8)-C(10)) with methanol in the presence of concentrated H(2)SO(4) as a catalyst has been studied in hydrodynamic cavitation reactor as well as in the sonochemical reactor. The different reaction operating parameters such as molar ratio of acid to alcohol, catalyst quantity have been optimized under acoustic as well as hydrodynamic cavitating conditions in addition to the optimization of the geometry of the orifice plate in the case of hydrodynamic cavitation reactors. Few experiments have also been carried out with other acid (lower and higher)/methanol combination viz. caprylic acid and capric acids with methanol with an aim of investigating the efficacy of cavitation for giving the desired yields and also to quantify the degree of process intensification that can be achieved using the same. It has been observed that ambient operating conditions of temperature and pressure and reaction times of 90% conversion (mol%). This clearly establishes the efficacy of cavitation as an excellent way to achieve process intensification of the biodiesel synthesis process.

Teleconnections associated with the intensification of the Australian monsoon during El Nino Modoki events

International Nuclear Information System (INIS)

Taschetto, A S; Gupta, A Sen; Ummenhofer, C C; England, M H; Haarsma, R J

2010-01-01

In this study we investigate the teleconnection between the central-western Pacific sea surface temperature (SST) warming, characteristic of El Nino Modoki events, and Australian rainfall using observations and atmospheric general circulation model experiments. During Modoki events, wet conditions are generally observed over northwestern Australia at the peak of the monsoon season (i.e. January and February) while dry conditions occur in the shoulder-months (i.e. December and March). This results in a shorter but more intense monsoon season over northwestern Australia relative to the climatology. We show that, apart from the well-known displacement of the Walker circulation, the anomalous warming in the central-western equatorial Pacific also induces a westward-propagating disturbance associated with a Gill-type mechanism. This in turn generates an anomalous cyclonic circulation over northwestern Australia that reinforces the climatological mean conditions during the peak of the monsoon season. The anomalous circulation leads to convergence of moisture and increased precipitation over northern Australia. This response, however, only occurs persistently during austral summer when the South Pacific Convergence Zone is climatologically strengthened, phase-locking the Gill-type response to the seasonal cycle. The interaction between the interannual SST variability during El Nino Modoki events and the evolution of the seasonal cycle intensifies deep convection in the central-west Pacific, driving a Gill-type response to diabatic heating. The intensified monsoonal rainfall occurs strongly in February due to the climatological wind conditions that are normally cyclonic over northwestern Australia.

Method of relative comparison of the thermohydraulic efficiency of heat exchange intensification in channels of heat-exchange surfaces

International Nuclear Information System (INIS)

Dubrovskij, E.V.; Vasil'ev, V.Ya.

2002-01-01

One introduces a technique to compare relatively thermohydraulic efficiency of heat transfer intensification in channels of heat exchange surfaces of any design types. It is shown that one should compare thermohydraulic efficiency of heat exchange intensification as to the thermal power of heat exchangers and pressure losses in channels with turbulators and in polished channels of heat exchange surfaces on the basis of dimensions of heat exchangers, their heat exchange surfaces and at similar (as to Re numbers) modes of coolant flow [ru

An Integrated, Multi-Stage, Multi-Scale Framework for Achieving Sustainable Process Synthesis-Intensification-Control

DEFF Research Database (Denmark)

Babi, Deenesh Kavi; Kumar Tula, Anjan; Mansouri, Seyed Soheil

The chemical and biochemical industry needs major reductions in energy consumption, waste generation, etc., in order to remain competitive through the design and operation of more sustainable chemical and biochemical processes. These required reductions can be addressed through process synthesis......-intensification-control, that is, the efficient use of raw materials (feedstock), the use of sustainable technologies and the design (and control) of processes that directly impact and improves sustainability/LCA factors. The unit operations concept, which has been sufficient until now, is one of the most used for performing...... process synthesis (and intensification) because it allows the association of tasks (functions) with the processing route to be followed. At the unit operations scale (Jaksland et al., 1995) and task scale (Siirola, 1996) alternatives are limited to existing (well-known) unit operations and therefore, may...

Process intensification on membrane-based process for blackcurrant juice concentration

DEFF Research Database (Denmark)

Fjerbæk Søtoft, Lene; Rong, Ben-Guang; Christensen, Knud Villy

Juice concentrate production is a field where process intensification and novel concentration processes need to be implemented. The paper presents a systematic approach for process synthesis based on membrane processes for the concentration of blackcurrant juice, exemplified by the aroma recovery...... using combinations of vacuum membrane distillation and traditional distillation. Furthermore, the paper further suggests a novel method for the combination of nanofiltration, reverse osmosis and membrane distillation for the concentration of the dearomatized juice....

Coupled social and ecological outcomes of land use change and agricultural intensification in Costa Rica and the future of biodiversity conservation in tropical agricultural regions.

Science.gov (United States)

Sanfiorenzo, A. R.; Shaver, I.; Chain Guadarrama, A.; Cleary, K.; Santiago-Garcia, R.; Finegan, B.; Hormel, L.; Sibelet, N.; Vierling, L. A.; Bosque-Perez, N.; DeClerck, F.; Fagan, M. E.; Waits, L.

2017-12-01

Tropical ecosystem conversion to agriculture has caused widespread habitat loss and created fragmented landscapes composed of remnant forest patches embedded in a matrix of agricultural land uses. Non- traditional agricultural export (NTAE) crops such as pineapple are rapidly replacing multiuse landscapes characterized by a diverse matrix of pasture and smallholder crops with intensive, large-scale, monoculture plantations. Using an interdisciplinary approach, we conduct a case study to examine the coupled social and ecological implications of LUCC and agricultural intensification in this region, with larger application to regions experiencing similar patterns. Guided by frameworks from both political and landscape ecology, we: (1) describe the social and economic implications of pineapple expansion, specifically the concentration of land, labor and financial resources, (2) quantify pineapple cultivation's spatial characteristics, and (3) assess the effects of pineapple expansion on surrounding forest ecosystems, on the agricultural matrix and on biodiversity conservation. Our results indicate that pineapple production concentrates land, labor, and financial resources, which has a homogenizing effect on the agricultural economy in the study region. This constrains farm-based livelihoods, with larger implications for food security and agricultural diversity. Landscape ecology analyses further reveal how pineapple production simplifies and homogenizes the agricultural matrix between forest patches, which is likely to have a negative effect on biodiversity. To offset the effects of pineapple expansion on social and environmental systems, we recommend developing landscape level land use planning capacity. Furthermore, agricultural and conservation policy reform is needed to promote landscape heterogeneity and economic diversity within the agricultural sector. Our interdisciplinary research provides a detailed examination of the social and ecological impacts of

Modeled seasonality of glacial abrupt climate events

Energy Technology Data Exchange (ETDEWEB)

Flueckiger, Jacqueline [Institute of Arctic and Alpine Research, University of Colorado, Boulder, CO (United States); Environmental Physics, Institute of Biogeochemistry and Pollutant Dynamics, ETH Zuerich, Zurich (Switzerland); Knutti, Reto [Institute for Atmospheric and Climate Science, ETH Zuerich, Zurich (Switzerland); White, James W.C. [Institute of Arctic and Alpine Research, University of Colorado, Boulder, CO (United States); Renssen, Hans [Vrije Universiteit Amsterdam, Faculty of Earth and Life Sciences, Amsterdam (Netherlands)

2008-11-15

Greenland ice cores, as well as many other paleo-archives from the northern hemisphere, recorded a series of 25 warm interstadial events, the so-called Dansgaard-Oeschger (D-O) events, during the last glacial period. We use the three-dimensional coupled global ocean-atmosphere-sea ice model ECBILT-CLIO and force it with freshwater input into the North Atlantic to simulate abrupt glacial climate events, which we use as analogues for D-O events. We focus our analysis on the Northern Hemisphere. The simulated events show large differences in the regional and seasonal distribution of the temperature and precipitation changes. While the temperature changes in high northern latitudes and in the North Atlantic region are dominated by winter changes, the largest temperature increases in most other land regions are seen in spring. Smallest changes over land are found during the summer months. Our model simulations also demonstrate that the temperature and precipitation change patterns for different intensifications of the Atlantic meridional overturning circulation are not linear. The extent of the transitions varies, and local non-linearities influence the amplitude of the annual mean response as well as the response in different seasons. Implications for the interpretation of paleo-records are discussed. (orig.)

Ecological intensification of cereal production systems: yield potential, soil quality, and precision agriculture.

Science.gov (United States)

Cassman, K G

1999-05-25

Wheat (Triticum aestivum L.), rice (Oryza sativa L.), and maize (Zea mays L.) provide about two-thirds of all energy in human diets, and four major cropping systems in which these cereals are grown represent the foundation of human food supply. Yield per unit time and land has increased markedly during the past 30 years in these systems, a result of intensified crop management involving improved germplasm, greater inputs of fertilizer, production of two or more crops per year on the same piece of land, and irrigation. Meeting future food demand while minimizing expansion of cultivated area primarily will depend on continued intensification of these same four systems. The manner in which further intensification is achieved, however, will differ markedly from the past because the exploitable gap between average farm yields and genetic yield potential is closing. At present, the rate of increase in yield potential is much less than the expected increase in demand. Hence, average farm yields must reach 70-80% of the yield potential ceiling within 30 years in each of these major cereal systems. Achieving consistent production at these high levels without causing environmental damage requires improvements in soil quality and precise management of all production factors in time and space. The scope of the scientific challenge related to these objectives is discussed. It is concluded that major scientific breakthroughs must occur in basic plant physiology, ecophysiology, agroecology, and soil science to achieve the ecological intensification that is needed to meet the expected increase in food demand.

Sustainable intensification in agriculture as a factor of achieving food security

Directory of Open Access Journals (Sweden)

Đurić Katarina

2016-01-01

Full Text Available Ending hunger, achieving food security and promoting sustainable development are at the top of the list of United Nations sustainable global development priorities after 2015. In addition to many positive effects, efforts of mankind regarding the reduction of rural poverty realized through the Green Revolution have had many negative effects, primarily related to natural resources. Irreversible devastation of land, air and water quality deterioration and jeopardizing biodiversity have been recognized as key elements of unsustainability of existing agricultural development concept. Consequently, there is a need for the adoption of a new concept of agricultural development, which will lie between intensive conventional and organic farming. The concept which has already been applied in some regions of the world and whose basic goal is to find a way to increase production with a negligible negative impact on the environment is sustainable agricultural intensification. The aim of this paper is to look at both positive and negative aspects of biotechnology development so far and point out the place and role the sustainable intensification concept should have in relation to conservation of natural resources and achievement of food security.

Food security as a function of Sustainable Intensification of Crop Production

Directory of Open Access Journals (Sweden)

Theodor Friedrich

2016-05-01

Full Text Available The challenge to eradicate hunger and establish food security across all its four pillars (availability, accessibility, health and safety, and continuity is ongoing. The actual situation in global food production leads most of the attention to improving accessibility and safety of food, particularly to vulnerable populations. However, in view of the growth in demand, which includes changes in preferences for example towards food of animal origin, availability and continuity will play larger roles in future. Food production needs to increase over the coming decades at challenging rates, while facing problems of degradation and reduced availability of natural resources for production such as soil and water, and facing increasing challenges from climate change. The actual trends in yield development suggest that a simple gradual improvement of production within the existing concepts will not provide a sustainable or feasible solution, and that more fundamental changes in the agricultural production paradigm are required to face these future challenges. The Sustainable Intensification represents such a change in paradigm in which high production levels are combined with sustainability. The concept of sustainable intensification, the rationale for it and its functional elements, represented by Conservation Agriculture, are presented in this paper.

Hard diffraction and rapidity gaps

International Nuclear Information System (INIS)

Brandt, A.

1995-09-01

The field of hard diffraction, which studies events with a rapidity gap and a hard scattering, has expanded dramatically recently. A review of new results from CDF, D OE, H1 and ZEUS will be given. These results include diffractive jet production, deep-inelastic scattering in large rapidity gap events, rapidity gaps between high transverse energy jets, and a search for diffractive W-boson production. The combination of these results gives new insight into the exchanged object, believed to be the pomeron. The results axe consistent with factorization and with a hard pomeron that contains both quarks and gluons. There is also evidence for the exchange of a strongly interacting color singlet in high momentum transfer (36 2 ) events

Process synthesis and intensification of hybrid separations

DEFF Research Database (Denmark)

Errico, Massimiliano

2017-01-01

Hybrid flowsheets are defined, in the context of process intensification, as alternatives suitable for replacing energy-intensive separation methods through the combination of more than one unit operation. Distillation is one of the first options considered for achieving a required separation...... and commented on. The corresponding distillation-based processes are considered for comparison. Synthesis of the possible hybrid flowsheets appears to be important, especially when multicomponent mixtures are considered. This aspect is discussed for the combination of liquid-liquid extraction and distillation...... as applied to the separation of biobutanol from its fermentation broth. The synthesis of alternative hybrid flowsheets is reported, showing that one configuration can realize a 43% reduction in the total annual cost. Bioalcohol production by fermentation perfectly represents the casewhere distillation alone...

Process Intensification for Cellulosic Biorefineries.

Science.gov (United States)

Sadula, Sunitha; Athaley, Abhay; Zheng, Weiqing; Ierapetritou, Marianthi; Saha, Basudeb

2017-06-22

Utilization of renewable carbon source, especially non-food biomass is critical to address the climate change and future energy challenge. Current chemical and enzymatic processes for producing cellulosic sugars are multistep, and energy- and water-intensive. Techno-economic analysis (TEA) suggests that upstream lignocellulose processing is a major hurdle to the economic viability of the cellulosic biorefineries. Process intensification, which integrates processes and uses less water and energy, has the potential to overcome the aforementioned challenges. Here, we demonstrate a one-pot depolymerization and saccharification process of woody biomass, energy crops, and agricultural residues to produce soluble sugars with high yields. Lignin is separated as a solid for selective upgrading. Further integration of our upstream process with a reactive extraction step makes energy-efficient separation of sugars in the form of furans. TEA reveals that the process efficiency and integration enable, for the first time, economic production of feed streams that could profoundly improve process economics for downstream cellulosic bioproducts. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Intensification of Evaporation and Condensation Processes in Heat Exchange Apparatus

Directory of Open Access Journals (Sweden)

L. L. Vasiliev

2005-01-01

Full Text Available The paper describes proposed design solutions for an intensification of heat transfer in evaporation and condensation heat exchangers. Complex experimental research of heat and mass transfer processes in flat and round cross-section miniature heat pipes is carried out. Optimization, development, manufacturing and an experimental investigation of copper miniature heat pipes with sintered powder are executed. Investigation results of capillary-porous structure properties that are used in evaporation and condensation heat-exchange apparatus are presented.

Adoptability of sustainable intensification technologies in dryland smallholder farming systems of West Africa

NARCIS (Netherlands)

Woittiez, L.S.; Descheemaeker, K.K.E.; Giller, K.E.

2015-01-01

Within the framework of CGIAR Research Program (CRP) 1.1: Dryland Systems, the compilation of a review of options, constraints and potential for agricultural intensification at a number of specific sites in West African dryland areas has been requested, using an integrated systems approach. CRP 1.1

Legume integration as an agroecological intensification option for smallholders in uplands of Southeast Asia

DEFF Research Database (Denmark)

Yap, Von Yi

to intensification. Ricebean (Vigna umbellata L.) was the most preferred legume species among the others to be integrated with maize due to its high selling price, ease to grow and harvest, stable market demand and ability to improve soil fertility. The results from researcher-managed field trial demonstrated......The transition from swidden agriculture to intensive maize (Zea mays L.) monoculture in upland regions of Southeast Asia has led to declining soil fertility problem, which necessitates the use of external nutrient inputs to sustain crop productivity. Conventional intensification via the use...... cropping represented low-external-input intensive farming systems, and the villages in northern Laos that cultivated maize with a short fallow period represented low-input farming systems. Data were collected from field surveys, a set of researcher- and farmer-managed field trials under rain-fed conditions...

Intensification of antiretroviral treatment with raltegravir for pregnant women living with HIV at high risk of vertical transmission.

Science.gov (United States)

Puthanakit, Thanyawee; Thepnarong, Nattawan; Chaithongwongwatthana, Surasith; Anugulruengkitt, Suvaporn; Anunsittichai, Orawan; Theerawit, Tuangtip; Ubolyam, Sasiwimol; Pancharoen, Chitsanu; Phanuphak, Praphan

2018-04-01

Objectives:  The rate of vertical HIV transmission for women at high risk of HIV transmission stands at approximately 7.6%. In the present study we describe infant infection rates in women who had received raltegravir (RAL) intensification during pregnancy to a standard three-drug antiretroviral (ART) regimen in Thailand. Methods:  This prospective cohort study enrolled HIV-1-positive pregnant women at high risk of vertical transmission, as defined by (1) ART initiation at a gestational age (GA) ≥32 weeks or (2) HIV-1 RNA >1000 copies/mL at GA of 32-38 weeks while on ART. Women received a standard three-drug ART regimen with RAL intensification (400 mg twice daily) until delivery and continued on a three-drug ART regimen after delivery. Plasma HIV-1 RNA testing was performed before intensification and at delivery. Infant HIV-1 status was determined using DNA PCR at birth, and at 1, 2 and 4 months of life. Results:  Between February 2016 and November 2017, 154 pregnant women on ART were enrolled into the study with a median CD4 cell count and plasma HIV-1 RNA level of 382 cells/mm 3 and 4.0 log 10 copies/mL, respectively. The three-drug combination consisted of either a lopinavir/ritonavir- (53%) or efavirenz-based (43%) regimen. Median GA at time of RAL initiation was 34 weeks (interquartile range [IQR] 33-36) and median duration was 21 days (IQR 8-34). The proportion of women who had a plasma HIV-1 RNA HIV infection, three in utero and three peripartum. Overall vertical transmission rate was 3.9% (95% confidence interval [CI] 1.4-8.2). Conclusion:  The majority of high-risk pregnant women living with HIV-1 who had received RAL intensification achieved viral suppression at delivery with a relatively low rate of vertical transmission. This intensification strategy represents an option for prevention in HIV-positive women at high risk of vertical transmission.

Broad-band linear polarization and magnetic intensification in rotating magnetic stars

International Nuclear Information System (INIS)

Degl'Innocenti, M.L.; Calamai, G.; Degl'Innocenti, E.L.; Patriarchi, P.

1981-01-01

Magnetic intensification is proposed as a mechanism to explain the general features of the variable broad-band linear polarization emerging from rotating magnetic stars. This mechanism is studied in detail, and some efforts are made to investigate the wide variety of polarization diagrams that can result from it. Theoretical results are compared with direct observations of the variable magnetic star 53 Cam to determine its geometric and magnetic configuration

INTENSIFICATION OF HEAT- AND MASS TRANSFER IN EVAPORATION - CONDENSATION DEVICES

Directory of Open Access Journals (Sweden)

A. G. Kulakov

2005-01-01

Full Text Available Results of investigation of capillary structure properties used in evaporation – condensation devices are presented.Constructive solutions for intensification of heat transfer in evaporation and condensation heat exchangers are offered. The obtained heat transfer experimental data at film-type vapor conden-sation are generalized in criterion form.Description of general rule of heat and mass transfer processes in miniature heat pipes with three various capillary structures at wide range of operating parameters is given in the paper.

Intensification of delignification and subsequent hydrolysis for the fermentable sugar production from lignocellulosic biomass using ultrasonic irradiation.

Science.gov (United States)

Subhedar, Preeti B; Ray, Pearl; Gogate, Parag R

2018-01-01

The present work deals with intensification of delignification and subsequent enzymatic hydrolysis of sustainable biomass such as groundnut shells, coconut coir and pistachio shells using ultrasound assisted approach so as to develop an economical approach for obtaining bioethanol. Process intensification, in the current context, is referred to as any improvements giving enhanced rates possibly with lower energy and chemical as well as enzyme requirement for delignification and hydrolysis respectively. Conventional processing for both delignification and enzymatic hydrolysis has also been investigated for establishing the degree of intensification. The obtained results for delignification of biomass established that for conventional alkaline treatment, the extent of delignification for the case of groundnut shells, coconut coir and pistachio shells were 41.8, 45.9 and 38% which increased to 71.1, 89.5 and 78.9% respectively giving almost 80-100% increase for the ultrasound assisted approach. Under optimized conditions, the conventional approach resulted in reducing sugar yields as 10.2, 12.1 and 8.1g/L for groundnut shells, coconut coir and pistachio shells respectively whereas for the case of ultrasound-assisted enzymatic hydrolysis, the obtained yields were 21.3, 23.9 and 18.4g/L in same order of biomass. The material samples were characterized by several characterization techniques for establishing the morphological changes obtained due to the use of ultrasound which were found to be favorable for enhanced delignification and hydrolysis for the ultrasound assisted approach. Overall, the results of this work establish the process intensification benefits due to the application of ultrasound for different sustainable biomass with mechanistic understanding based on the morphological analyses. Copyright © 2017 Elsevier B.V. All rights reserved.

Home blood pressure monitoring, secure electronic messaging and medication intensification for improving hypertension control: a mediation analysis.

Science.gov (United States)

Ralston, J D; Cook, A J; Anderson, M L; Catz, S L; Fishman, P A; Carlson, J; Johnson, R; Green, B B

2014-01-01

We evaluated the role of home monitoring, communication with pharmacists, medication intensification, medication adherence and lifestyle factors in contributing to the effectiveness of an intervention to improve blood pressure control in patients with uncontrolled essential hypertension. We performed a mediation analysis of a published randomized trial based on the Chronic Care Model delivered over a secure patient website from June 2005 to December 2007. Study arms analyzed included usual care with a home blood pressure monitor and usual care with home blood pressure monitor and web-based pharmacist care. Mediator measures included secure messaging and telephone encounters; home blood pressure monitoring; medications intensification and adherence and lifestyle factors. Overall fidelity to the Chronic Care Model was assessed with the Patient Assessment of Chronic Care (PACIC) instrument. The primary outcome was percent of participants with blood pressure (BP) <140/90 mm Hg. At 12 months follow-up, patients in the web-based pharmacist care group were more likely to have BP <140/90 mm Hg (55%) compared to patients in the group with home blood pressure monitors only (37%) (p = 0.001). Home blood pressure monitoring accounted for 30.3% of the intervention effect, secure electronic messaging accounted for 96%, and medication intensification for 29.3%. Medication adherence and self-report of fruit and vegetable intake and weight change were not different between the two study groups. The PACIC score accounted for 22.0 % of the main intervention effect. The effect of web-based pharmacist care on improved blood pressure control was explained in part through a combination of home blood pressure monitoring, secure messaging, and antihypertensive medication intensification.

Driving Roles of Tropospheric and Stratospheric Thermal Anomalies in Intensification and Persistence of the Arctic Superstorm in 2012

Science.gov (United States)

Tao, Wei; Zhang, Jing; Fu, Yunfei; Zhang, Xiangdong

2017-10-01

Intense synoptic-scale storms have been more frequently observed over the Arctic during recent years. Specifically, a superstorm hit the Arctic Ocean in August 2012 and preceded a new record low Arctic sea ice extent. In this study, the major physical processes responsible for the storm's intensification and persistence are explored through a series of numerical modeling experiments with the Weather Research and Forecasting model. It is found that thermal anomalies in troposphere as well as lower stratosphere jointly lead to the development of this superstorm. Thermal contrast between the unusually warm Siberia and the relatively cold Arctic Ocean results in strong troposphere baroclinicity and upper level jet, which contribute to the storm intensification initially. On the other hand, Tropopause Polar Vortex (TPV) associated with the thermal anomaly in lower stratosphere further intensifies the upper level jet and accordingly contributes to a drastic intensification of the storm. Stacking with the enhanced surface low, TPV intensifies further, which sustains the storm to linger over the Arctic Ocean for an extended period.

Process Intensification: A Perspective on Process Synthesis

DEFF Research Database (Denmark)

Lutze, Philip; Gani, Rafiqul; Woodley, John

2010-01-01

In recent years, process intensification (PI) has attracted considerable academic interest as a potential means for process improvement, to meet the increasing demands for sustainable production. A variety of intensified operations developed in academia and industry creates a large number...... of options to potentially improve the process but to identify the set of feasible solutions for PI in which the optimal can be found takes considerable resources. Hence, a process synthesis tool to achieve PI would potentially assist in the generation and evaluation of PI options. Currently, several process...... design tools with a clear focus on specific PI tasks exist. Therefore, in this paper, the concept of a general systematic framework for synthesis and design of PI options in hierarchical steps through analyzing an existing process, generating PI options in a superstructure and evaluating intensified...

Advances in Process Intensification through Multifunctional Reactor Engineering

Energy Technology Data Exchange (ETDEWEB)

O' Hern, Timothy [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Engineering Sciences Center; Evans, Lindsay [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Materials Sciences and Engineering Center; Miller, Jim [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Materials Sciences and Engineering Center; Cooper, Marcia [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Energetic Components Realization Center; Torczynski, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Pena, Donovan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gill, Walt [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Engineering Sciences Center

2011-02-01

This project was designed to advance the art of process intensification leading to a new generation of multifunctional chemical reactors utilizing pulse flow. Experimental testing was performed in order to fully characterize the hydrodynamic operating regimes associated with pulse flow for implementation in commercial applications. Sandia National Laboratories (SNL) operated a pilot-scale multifunctional reactor experiment for operation with and investigation of pulse flow operation. Validation-quality data sets of the fluid dynamics, heat and mass transfer, and chemical kinetics were acquired and shared with Chemical Research and Licensing (CR&L). Experiments in a two-phase air-water system examined the effects of bead diameter in the packing, and viscosity. Pressure signals were used to detect pulsing. Three-phase experiments used immiscible organic and aqueous liquids, and air or nitrogen as the gas phase. Hydrodynamic studies of flow regimes and holdup were performed for different types of packing, and mass transfer measurements were performed for a woven packing. These studies substantiated the improvements in mass transfer anticipated for pulse flow in multifunctional reactors for the acid-catalyzed C4 paraffin/olefin alkylation process. CR&L developed packings for this alkylation process, utilizing their alkylation process pilot facilities in Pasadena, TX. These packings were evaluated in the pilot-scale multifunctional reactor experiments established by Sandia to develop a more fundamental understanding of their role in process intensification. Lummus utilized the alkylation technology developed by CR&L to design and optimize the full commercial process utilizing multifunctional reactors containing the packings developed by CR&L and evaluated by Sandia. This hydrodynamic information has been developed for multifunctional chemical reactors utilizing pulse flow, for the acid-catalyzed C4 paraffin/olefin alkylation process, and is now accessible for use in

Colour reconnections and rapidity gaps

International Nuclear Information System (INIS)

Loennblad, Leif

1996-01-01

I argue that the success of recently proposed models describing events with large rapidity gaps in DIS at HERA in terms of non-perturbative colour exchange is heavily reliant on suppression of perturbative gluon emission in the proton direction. There is little or no physical motivation for such suppression and I show that a model without this suppression cannot describe the rapidity gap events at HERA. (author)

Process intensification effect of ball milling on the hydrothermal pretreatment for corn straw enzymolysis

International Nuclear Information System (INIS)

Yuan, Zhengqiu; Long, Jinxing; Wang, Tiejun; Shu, Riyang; Zhang, Qi; Ma, Longlong

2015-01-01

Highlights: • Novel pretreatment of ball milling combined with hydrothermal method was presented. • Intensification effect of ball milling was significant for corn straw enzymolysis. • Ball milling destroyed the physical structure of corn straw. • Chemical (liquid mixture) method removed lignin and hemicellulose. • Glucose yield increased from 0.41 to 13.86 mg mL −1 under the optimized condition. - Abstract: Enhancement of the cellulose accessibility is significant for biomass enzymatic hydrolysis. Here, we reported an efficient combined pretreatment for corn straw enzymolysis using ball milling and dilute acid hydrothermal method (a mixture solvent of H 2 O/ethanol/sulfuric acid/hydrogen peroxide liquid). The process intensification effect of ball milling on the pretreatment of the corn straw was studied through the comparative characterization of the physical–chemical properties of the raw and pretreated corn straw using FT-IR, BET, XRD, SEM, and HPLC analysis. The effect of the pretreatment temperature was also investigated. Furthermore, various pretreatment methods were compared as well. Moreover, the pretreatment performance was measured by enzymolysis. The results showed that ball milling had a significant process intensification effect on the corn straw enzymolysis. The glucose concentration was dramatically increased from 0.41 to 13.86 mg mL −1 after the combined treatment of ball milling and hydrothermal. The efficient removal of lignin and hemicellulose and the enlargement of the surface area were considered to be responsible for this significant increase based on the intensive analysis on the main components and the physical–chemical properties of the raw and pretreated corn straw

Integrating Remote Sensing Data, Hybrid-Cloud Computing, and Event Notifications for Advanced Rapid Imaging & Analysis (Invited)

Science.gov (United States)

Hua, H.; Owen, S. E.; Yun, S.; Lundgren, P.; Fielding, E. J.; Agram, P.; Manipon, G.; Stough, T. M.; Simons, M.; Rosen, P. A.; Wilson, B. D.; Poland, M. P.; Cervelli, P. F.; Cruz, J.

2013-12-01

Space-based geodetic measurement techniques such as Interferometric Synthetic Aperture Radar (InSAR) and Continuous Global Positioning System (CGPS) are now important elements in our toolset for monitoring earthquake-generating faults, volcanic eruptions, hurricane damage, landslides, reservoir subsidence, and other natural and man-made hazards. Geodetic imaging's unique ability to capture surface deformation with high spatial and temporal resolution has revolutionized both earthquake science and volcanology. Continuous monitoring of surface deformation and surface change before, during, and after natural hazards improves decision-making from better forecasts, increased situational awareness, and more informed recovery. However, analyses of InSAR and GPS data sets are currently handcrafted following events and are not generated rapidly and reliably enough for use in operational response to natural disasters. Additionally, the sheer data volumes needed to handle a continuous stream of InSAR data sets also presents a bottleneck. It has been estimated that continuous processing of InSAR coverage of California alone over 3-years would reach PB-scale data volumes. Our Advanced Rapid Imaging and Analysis for Monitoring Hazards (ARIA-MH) science data system enables both science and decision-making communities to monitor areas of interest with derived geodetic data products via seamless data preparation, processing, discovery, and access. We will present our findings on the use of hybrid-cloud computing to improve the timely processing and delivery of geodetic data products, integrating event notifications from USGS to improve the timely processing for response, as well as providing browse results for quick looks with other tools for integrative analysis.

Sustainable intensification of smallholder farming systems in Ethiopia : what roles can scattered trees play?

NARCIS (Netherlands)

Sida, Tesfaye Shiferaw

2018-01-01

Scattered trees dominate smallholder agricultural landscapes in Ethiopia, as in large parts of sub-Saharan Africa (SSA). While the integration of scattered trees with crops could provide a viable pathway for sustainable intensification of these farming systems, they also lead to trade- offs.

On-farm impact of the System of Rice Intensification (SRI): Evidence and knowledge gaps

NARCIS (Netherlands)

Berkhout, E.D.; Glover, D.B.A.; Kuyvenhoven, A.

2015-01-01

The System of Rice Intensification (SRI) is being promoted worldwide, but relatively little is yet known about its impacts at farm level. This article reviews available evidence on the impact of SRI practices in terms of yield and productivity. Adoption of SRI practices necessarily changes the mix

A systematic synthesis and design methodology to achieve process intensification in (bio) chemical processes

DEFF Research Database (Denmark)

Lutze, Philip; Roman Martinez, Alicia; Woodley, John

2012-01-01

Process intensification (PI) has the potential to improve existing processes or create new process options, which are needed in order to produce products using more sustainable methods. In principle, an enormous number of process options can be generated but where and how the process should be in...

A systematic synthesis and design methodology to achieve process intensification in (bio) chemical processes

DEFF Research Database (Denmark)

Lutze, Philip; Román-Martinez, Alicia; Woodley, John

2010-01-01

Process intensification (PI) has the potential to improve existing processes or create new process options which are needed in order to produce products using more sustainable methods. PI creates an enormous number of process options. In order to manage the complexity of options in which a feasib...

The dynamical interactions of Amazon deforestation, intensification of cattle ranching and technology adoption: insights from a socio-ecological model

Science.gov (United States)

Müller-Hansen, Finn; Heitzig, Jobst; Donges, Jonathan F.; Cardoso, Manoel F.; Kurths, Jürgen; Thonicke, Kirsten

2017-04-01

Deforestation in the tropics - with vast consequences for the ecosystem and climate - is mainly driven by subsequent land use, which is not only determined by environmental and economic constraints but also influenced by the use of different production technologies. Inefficient production technologies can lead to excessive use of land, especially in areas where land is easily available and accessible. Here, the adoption of new technologies could help to use already converted land more intensively and ease pressures on ecologically valuable areas. In this study, we take the Brazilian Amazon as a prominent example region to explore the interplay of land-use decisions with environmental and economic dynamics in the process of land-use intensification and frontier expansion. Expansion of pasture land for cattle ranching to satisfy increasing domestic and international demands is one of the important drivers for deforestation in the Brazilian Amazon. Pasture run-down and following land abandonment further drive the expansion of deforestation frontiers into pristine forests. Therefore, intensification of livestock production, especially better pasture management, could potentially reduce deforestation. However, a number of reasons including the large spatial extent of the region make the process of comparing the effectiveness of different management techniques, technologies and policies in the region difficult. Therefore, the effectiveness and possible outcomes of policies to foster intensification are highly debated in the literature. Some authors deny that intensification policies are a viable option to spare forests as long as they are not a scarce resource [1] while others insist that intensification has an effect if only supported by the right policies [2]. In this presentation, we introduce a concise agent-based model to study conditions under which intensification can reduce deforestation and explore the trade-offs between intensified and extensive land uses

Rounding, work intensification and new public management.

Science.gov (United States)

Willis, Eileen; Toffoli, Luisa; Henderson, Julie; Couzner, Leah; Hamilton, Patricia; Verrall, Claire; Blackman, Ian

2016-06-01

In this study, we argue that contemporary nursing care has been overtaken by new public management strategies aimed at curtailing budgets in the public hospital sector in Australia. Drawing on qualitative interviews with 15 nurses from one public acute hospital with supporting documentary evidence, we demonstrate what happens to nursing work when management imposes rounding as a risk reduction strategy. In the case study outlined rounding was introduced across all wards in response to missed care, which in turn arose as a result of work intensification produced by efficiency, productivity, effectiveness and accountability demands. Rounding is a commercially sponsored practice consistent with new public management. Our study illustrates the impact that new public management strategies such as rounding have on how nurses work, both in terms of work intensity and in who controls their labour. © 2015 John Wiley & Sons Ltd.

Intensification of the amethyst color by irradiation

International Nuclear Information System (INIS)

Gorski, Maria Silvia

2000-01-01

Brazil is great natural quartz producer. Amethyst, variety of the violet color is very appreciated in the world and since the Antiquity it is said to have many supernatural powers. Is the most highly valued stone in the quartz group and the graduation of the color is responsible for the commercial value that varies of US$ 0.5 to US$ 25.0 for carat. As carried through studies the violet color is related with the amount of Fe 4+ distributed in the crystal . The present work consists of the induction and intensification of the violet color by rays gamma of sources of Co-60 in quartz samples of diverse origins. It was used analyses by fluorescence for X-rays in samples of amethyst and citrine for the evaluation of the the iron and aluminium for the induction of the violet color. (author)

Metrics and methods for characterizing dairy farm intensification using farm survey data.

Science.gov (United States)

Gonzalez-Mejia, Alejandra; Styles, David; Wilson, Paul; Gibbons, James

2018-01-01

Evaluation of agricultural intensification requires comprehensive analysis of trends in farm performance across physical and socio-economic aspects, which may diverge across farm types. Typical reporting of economic indicators at sectorial or the "average farm" level does not represent farm diversity and provides limited insight into the sustainability of specific intensification pathways. Using farm business data from a total of 7281 farm survey observations of English and Welsh dairy farms over a 14-year period we calculate a time series of 16 key performance indicators (KPIs) pertinent to farm structure, environmental and socio-economic aspects of sustainability. We then apply principle component analysis and model-based clustering analysis to identify statistically the number of distinct dairy farm typologies for each year of study, and link these clusters through time using multidimensional scaling. Between 2001 and 2014, dairy farms have largely consolidated and specialized into two distinct clusters: more extensive farms relying predominantly on grass, with lower milk yields but higher labour intensity, and more intensive farms producing more milk per cow with more concentrate and more maize, but lower labour intensity. There is some indication that these clusters are converging as the extensive cluster is intensifying slightly faster than the intensive cluster, in terms of milk yield per cow and use of concentrate feed. In 2014, annual milk yields were 6,835 and 7,500 l/cow for extensive and intensive farm types, respectively, whilst annual concentrate feed use was 1.3 and 1.5 tonnes per cow. For several KPIs such as milk yield the mean trend across all farms differed substantially from the extensive and intensive typologies mean. The indicators and analysis methodology developed allows identification of distinct farm types and industry trends using readily available survey data. The identified groups allow the accurate evaluation of the consequences of the

Metrics and methods for characterizing dairy farm intensification using farm survey data.

Directory of Open Access Journals (Sweden)

Alejandra Gonzalez-Mejia

Full Text Available Evaluation of agricultural intensification requires comprehensive analysis of trends in farm performance across physical and socio-economic aspects, which may diverge across farm types. Typical reporting of economic indicators at sectorial or the "average farm" level does not represent farm diversity and provides limited insight into the sustainability of specific intensification pathways. Using farm business data from a total of 7281 farm survey observations of English and Welsh dairy farms over a 14-year period we calculate a time series of 16 key performance indicators (KPIs pertinent to farm structure, environmental and socio-economic aspects of sustainability. We then apply principle component analysis and model-based clustering analysis to identify statistically the number of distinct dairy farm typologies for each year of study, and link these clusters through time using multidimensional scaling. Between 2001 and 2014, dairy farms have largely consolidated and specialized into two distinct clusters: more extensive farms relying predominantly on grass, with lower milk yields but higher labour intensity, and more intensive farms producing more milk per cow with more concentrate and more maize, but lower labour intensity. There is some indication that these clusters are converging as the extensive cluster is intensifying slightly faster than the intensive cluster, in terms of milk yield per cow and use of concentrate feed. In 2014, annual milk yields were 6,835 and 7,500 l/cow for extensive and intensive farm types, respectively, whilst annual concentrate feed use was 1.3 and 1.5 tonnes per cow. For several KPIs such as milk yield the mean trend across all farms differed substantially from the extensive and intensive typologies mean. The indicators and analysis methodology developed allows identification of distinct farm types and industry trends using readily available survey data. The identified groups allow the accurate evaluation of the

Mental illness and intensification of diabetes medications: an observational cohort study

OpenAIRE

Frayne, Susan M; Holmes, Tyson H; Berg, Eric; Goldstein, Mary K; Berlowitz, Dan R; Miller, Donald R; Pogach, Leonard M; Laungani, Kaajal J; Lee, Tina T; Moos, Rudolf

2014-01-01

Background Mental health condition (MHC) comorbidity is associated with lower intensity care in multiple clinical scenarios. However, little is known about the effect of MHC upon clinicians? decisions about intensifying antiglycemic medications in diabetic patients with poor glycemic control. We examined whether delay in intensification of antiglycemic medications in response to an elevated Hemoglobin A1c (HbA1c) value is longer for patients with MHC than for those without MHC, and whether an...

The Intensification of Work in Spain (2007-2011: Teamwork and Flexibility

Directory of Open Access Journals (Sweden)

Teamwork

2017-01-01

Full Text Available In this article, we analyse the relationship between the intensification of work and organizational flexibility. Specifically, we focus on teamwork, considered as an emblematic organizational strategy of flexible and efficient organizations. The relationship between teamwork, intensity of work and stress is examined using data from Spain's National Survey on Working Conditions. Based on the results, we propose that analysis of the intensity of work be incorporated into social dialogue and the prevention of occupational risks.

Diagnosis for ecological intensification of maize-based smallholder farming systems in the Costa Chica, Mexico

NARCIS (Netherlands)

Flores-Sanchez, D.; Kleine Koerkamp-Rabelista, J.; Navarro-Garza, H.; Lantinga, E.A.; Groot, J.C.J.; Kropff, M.J.; Rossing, W.A.H.

2011-01-01

Enhanced utilization of ecological processes for food and feed production as part of the notion of ecological intensification starts from location-specific knowledge of production constraints. A diagnostic systems approach which combined social-economic and production ecological methods at farm and

Study of dijet events with a large rapidity gap between the two leading jets in pp collisions at √{s}=7 {TeV}

Science.gov (United States)

Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Asilar, E.; Bergauer, T.; Brandstetter, J.; Brondolin, E.; Dragicevic, M.; Erö, J.; Flechl, M.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Hartl, C.; Hörmann, N.; Hrubec, J.; Jeitler, M.; König, A.; Krätschmer, I.; Liko, D.; Matsushita, T.; Mikulec, I.; Rabady, D.; Rad, N.; Rahbaran, B.; Rohringer, H.; Schieck, J.; Strauss, J.; Waltenberger, W.; Wulz, C.-E.; Dvornikov, O.; Makarenko, V.; Mossolov, V.; Suarez Gonzalez, J.; Zykunov, V.; Shumeiko, N.; Alderweireldt, S.; De Wolf, E. A.; Janssen, X.; Lauwers, J.; Van De Klundert, M.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Van Spilbeeck, A.; Abu Zeid, S.; Blekman, F.; D'Hondt, J.; Daci, N.; De Bruyn, I.; Deroover, K.; Lowette, S.; Moortgat, S.; Moreels, L.; Olbrechts, A.; Python, Q.; Skovpen, K.; Tavernier, S.; Van Doninck, W.; Van Mulders, P.; Van Parijs, I.; Brun, H.; Clerbaux, B.; De Lentdecker, G.; Delannoy, H.; Fasanella, G.; Favart, L.; Goldouzian, R.; Grebenyuk, A.; Karapostoli, G.; Lenzi, T.; Léonard, A.; Luetic, J.; Maerschalk, T.; Marinov, A.; Randle-conde, A.; Seva, T.; Vander Velde, C.; Vanlaer, P.; Vannerom, D.; Yonamine, R.; Zenoni, F.; Zhang, F.; Cimmino, A.; Cornelis, T.; Dobur, D.; Fagot, A.; Gul, M.; Khvastunov, I.; Poyraz, D.; Salva, S.; Schöfbeck, R.; Tytgat, M.; Van Driessche, W.; Yazgan, E.; Zaganidis, N.; Bakhshiansohi, H.; Beluffi, C.; Bondu, O.; Brochet, S.; Bruno, G.; Caudron, A.; De Visscher, S.; Delaere, C.; Delcourt, M.; Francois, B.; Giammanco, A.; Jafari, A.; Komm, M.; Krintiras, G.; Lemaitre, V.; Magitteri, A.; Mertens, A.; Musich, M.; Piotrzkowski, K.; Quertenmont, L.; Selvaggi, M.; Vidal Marono, M.; Wertz, S.; Beliy, N.; Aldá Júnior, W. L.; Alves, F. L.; Alves, G. A.; Brito, L.; Hensel, C.; Moraes, A.; Pol, M. E.; Rebello Teles, P.; Belchior Batista Das Chagas, E.; Carvalho, W.; Chinellato, J.; Custódio, A.; Da Costa, E. M.; Da Silveira, G. G.; De Jesus Damiao, D.; De Oliveira Martins, C.; De Souza, S. Fonseca; Huertas Guativa, L. M.; Malbouisson, H.; Matos Figueiredo, D.; Mora Herrera, C.; Mundim, L.; Nogima, H.; Prado Da Silva, W. L.; Santoro, A.; Sznajder, A.; Tonelli Manganote, E. J.; De Araujo, F. Torres Da Silva; Pereira, A. Vilela; Ahuja, S.; Bernardes, C. A.; Dogra, S.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Mercadante, P. G.; Moon, C. S.; Novaes, S. F.; Padula, Sandra S.; Romero Abad, D.; Ruiz Vargas, J. C.; Aleksandrov, A.; Hadjiiska, R.; Iaydjiev, P.; Rodozov, M.; Stoykova, S.; Sultanov, G.; Vutova, M.; Dimitrov, A.; Glushkov, I.; Litov, L.; Pavlov, B.; Petkov, P.; Fang, W.; Ahmad, M.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Chen, Y.; Cheng, T.; Jiang, C. H.; Leggat, D.; Liu, Z.; Romeo, F.; Ruan, M.; Shaheen, S. M.; Spiezia, A.; Tao, J.; Wang, C.; Wang, Z.; Zhang, H.; Zhao, J.; Ban, Y.; Chen, G.; Li, Q.; Liu, S.; Mao, Y.; Qian, S. J.; Wang, D.; Xu, Z.; Avila, C.; Cabrera, A.; Chaparro Sierra, L. F.; Florez, C.; Gomez, J. P.; González Hernández, C. F.; Ruiz Alvarez, J. D.; Sanabria, J. C.; Godinovic, N.; Lelas, D.; Puljak, I.; Ribeiro Cipriano, P. M.; Sculac, T.; Antunovic, Z.; Kovac, M.; Brigljevic, V.; Ferencek, D.; Kadija, K.; Mesic, B.; Susa, T.; Ather, M. W.; Attikis, A.; Mavromanolakis, G.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Rykaczewski, H.; Finger, M.; Finger, M.; Carrera Jarrin, E.; Elgammal, S.; Ellithi Kamel, A.; Mohamed, A.; Kadastik, M.; Perrini, L.; Raidal, M.; Tiko, A.; Veelken, C.; Eerola, P.; Pekkanen, J.; Voutilainen, M.; Härkönen, J.; Järvinen, T.; Karimäki, V.; Kinnunen, R.; Lampén, T.; Lassila-Perini, K.; Lehti, S.; Lindén, T.; Luukka, P.; Tuominiemi, J.; Tuovinen, E.; Wendland, L.; Talvitie, J.; Tuuva, T.; Besancon, M.; Couderc, F.; Dejardin, M.; Denegri, D.; Fabbro, B.; Faure, J. L.; Favaro, C.; Ferri, F.; Ganjour, S.; Ghosh, S.; Givernaud, A.; Gras, P.; de Monchenault, G. Hamel; Jarry, P.; Kucher, I.; Locci, E.; Machet, M.; Malcles, J.; Rander, J.; Rosowsky, A.; Titov, M.; Abdulsalam, A.; Antropov, I.; Baffioni, S.; Beaudette, F.; Busson, P.; Cadamuro, L.; Chapon, E.; Charlot, C.; Davignon, O.; de Cassagnac, R. Granier; Jo, M.; Lisniak, S.; Miné, P.; Nguyen, M.; Ochando, C.; Ortona, G.; Paganini, P.; Pigard, P.; Regnard, S.; Salerno, R.; Sirois, Y.; Leiton, A. G. Stahl; Strebler, T.; Yilmaz, Y.; Zabi, A.; Zghiche, A.; Agram, J.-L.; Andrea, J.; Bloch, D.; Brom, J.-M.; Buttignol, M.; Chabert, E. C.; Chanon, N.; Collard, C.; Conte, E.; Coubez, X.; Fontaine, J.-C.; Gelé, D.; Goerlach, U.; Bihan, A.-C. Le; Van Hove, P.; Gadrat, S.; Beauceron, S.; Bernet, C.; Boudoul, G.; Carrillo Montoya, C. A.; Chierici, R.; Contardo, D.; Courbon, B.; Depasse, P.; El Mamouni, H.; Fay, J.; Gascon, S.; Gouzevitch, M.; Grenier, G.; Ille, B.; Lagarde, F.; Laktineh, I. B.; Lethuillier, M.; Mirabito, L.; Pequegnot, A. L.; Perries, S.; Popov, A.; Sordini, V.; Vander Donckt, M.; Verdier, P.; Viret, S.; Toriashvili, T.; Tsamalaidze, Z.; Autermann, C.; Beranek, S.; Feld, L.; Kiesel, M. K.; Klein, K.; Lipinski, M.; Preuten, M.; Schomakers, C.; Schulz, J.; Verlage, T.; Albert, A.; Brodski, M.; Dietz-Laursonn, E.; Duchardt, D.; Endres, M.; Erdmann, M.; Erdweg, S.; Esch, T.; Fischer, R.; Güth, A.; Hamer, M.; Hebbeker, T.; Heidemann, C.; Hoepfner, K.; Knutzen, S.; Merschmeyer, M.; Meyer, A.; Millet, P.; Mukherjee, S.; Olschewski, M.; Padeken, K.; Pook, T.; Radziej, M.; Reithler, H.; Rieger, M.; Scheuch, F.; Sonnenschein, L.; Teyssier, D.; Thüer, S.; Cherepanov, V.; Flügge, G.; Kargoll, B.; Kress, T.; Künsken, A.; Lingemann, J.; Müller, T.; Nehrkorn, A.; Nowack, A.; Pistone, C.; Pooth, O.; Stahl, A.; Aldaya Martin, M.; Arndt, T.; Asawatangtrakuldee, C.; Beernaert, K.; Behnke, O.; Behrens, U.; Bin Anuar, A. A.; Borras, K.; Campbell, A.; Connor, P.; Contreras-Campana, C.; Costanza, F.; Pardos, C. Diez; Dolinska, G.; Eckerlin, G.; Eckstein, D.; Eichhorn, T.; Eren, E.; Gallo, E.; Garay Garcia, J.; Geiser, A.; Gizhko, A.; Grados Luyando, J. M.; Grohsjean, A.; Gunnellini, P.; Harb, A.; Hauk, J.; Hempel, M.; Jung, H.; Kalogeropoulos, A.; Karacheban, O.; Kasemann, M.; Keaveney, J.; Kleinwort, C.; Korol, I.; Krücker, D.; Lange, W.; Lelek, A.; Lenz, T.; Leonard, J.; Lipka, K.; Lobanov, A.; Lohmann, W.; Mankel, R.; Melzer-Pellmann, I.-A.; Meyer, A. B.; Mittag, G.; Mnich, J.; Mussgiller, A.; Pitzl, D.; Placakyte, R.; Raspereza, A.; Roland, B.; Sahin, M. Ö.; Saxena, P.; Schoerner-Sadenius, T.; Spannagel, S.; Stefaniuk, N.; Van Onsem, G. P.; Walsh, R.; Wissing, C.; Blobel, V.; Centis Vignali, M.; Draeger, A. R.; Dreyer, T.; Garutti, E.; Gonzalez, D.; Haller, J.; Hoffmann, M.; Junkes, A.; Klanner, R.; Kogler, R.; Kovalchuk, N.; Lapsien, T.; Marchesini, I.; Marconi, D.; Meyer, M.; Niedziela, M.; Nowatschin, D.; Pantaleo, F.; Peiffer, T.; Perieanu, A.; Scharf, C.; Schleper, P.; Schmidt, A.; Schumann, S.; Schwandt, J.; Stadie, H.; Steinbrück, G.; Stober, F. M.; Stöver, M.; Tholen, H.; Troendle, D.; Usai, E.; Vanelderen, L.; Vanhoefer, A.; Vormwald, B.; Akbiyik, M.; Barth, C.; Baur, S.; Baus, C.; Berger, J.; Butz, E.; Caspart, R.; Chwalek, T.; Colombo, F.; De Boer, W.; Dierlamm, A.; Fink, S.; Freund, B.; Friese, R.; Giffels, M.; Gilbert, A.; Goldenzweig, P.; Haitz, D.; Hartmann, F.; Heindl, S. M.; Husemann, U.; Kassel, F.; Katkov, I.; Kudella, S.; Mildner, H.; Mozer, M. U.; Müller, Th.; Plagge, M.; Quast, G.; Rabbertz, K.; Röcker, S.; Roscher, F.; Schröder, M.; Shvetsov, I.; Sieber, G.; Simonis, H. J.; Ulrich, R.; Wayand, S.; Weber, M.; Weiler, T.; Williamson, S.; Wöhrmann, C.; Wolf, R.; Anagnostou, G.; Daskalakis, G.; Geralis, T.; Giakoumopoulou, V. A.; Kyriakis, A.; Loukas, D.; Topsis-Giotis, I.; Kesisoglou, S.; Panagiotou, A.; Saoulidou, N.; Tziaferi, E.; Evangelou, I.; Flouris, G.; Foudas, C.; Kokkas, P.; Loukas, N.; Manthos, N.; Papadopoulos, I.; Paradas, E.; Filipovic, N.; Pasztor, G.; Bencze, G.; Hajdu, C.; Horvath, D.; Sikler, F.; Veszpremi, V.; Vesztergombi, G.; Zsigmond, A. J.; Beni, N.; Czellar, S.; Karancsi, J.; Makovec, A.; Molnar, J.; Szillasi, Z.; Bartók, M.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Komaragiri, J. R.; Bahinipati, S.; Bhowmik, S.; Choudhury, S.; Mal, P.; Mandal, K.; Nayak, A.; Sahoo, D. K.; Sahoo, N.; Swain, S. K.; Bansal, S.; Beri, S. B.; Bhatnagar, V.; Bhawandeep, U.; Chawla, R.; Kalsi, A. K.; Kaur, A.; Kaur, M.; Kumar, R.; Kumari, P.; Mehta, A.; Mittal, M.; Singh, J. B.; Walia, G.; Kumar, Ashok; Bhardwaj, A.; Choudhary, B. C.; Garg, R. B.; Keshri, S.; Malhotra, S.; Naimuddin, M.; Ranjan, K.; Sharma, R.; Sharma, V.; Bhattacharya, R.; Bhattacharya, S.; Chatterjee, K.; Dey, S.; Dutt, S.; Dutta, S.; Ghosh, S.; Majumdar, N.; Modak, A.; Mondal, K.; Mukhopadhyay, S.; Nandan, S.; Purohit, A.; Roy, A.; Roy, D.; Roy Chowdhury, S.; Sarkar, S.; Sharan, M.; Thakur, S.; Behera, P. K.; Chudasama, R.; Dutta, D.; Jha, V.; Kumar, V.; Mohanty, A. K.; Netrakanti, P. K.; Pant, L. M.; Shukla, P.; Topkar, A.; Aziz, T.; Dugad, S.; Kole, G.; Mahakud, B.; Mitra, S.; Mohanty, G. B.; Parida, B.; Sur, N.; Sutar, B.; Banerjee, S.; Dewanjee, R. K.; Ganguly, S.; Guchait, M.; Jain, Sa.; Kumar, S.; Maity, M.; Majumder, G.; Mazumdar, K.; Sarkar, T.; Wickramage, N.; Chauhan, S.; Dube, S.; Hegde, V.; Kapoor, A.; Kothekar, K.; Pandey, S.; Rane, A.; Sharma, S.; Chenarani, S.; Eskandari Tadavani, E.; Etesami, S. M.; Khakzad, M.; Mohammadi Najafabadi, M.; Naseri, M.; Paktinat Mehdiabadi, S.; Rezaei Hosseinabadi, F.; Safarzadeh, B.; Zeinali, M.; Felcini, M.; Grunewald, M.; Abbrescia, M.; Calabria, C.; Caputo, C.; Colaleo, A.; Creanza, D.; Cristella, L.; De Filippis, N.; De Palma, M.; Fiore, L.; Iaselli, G.; Maggi, G.; Maggi, M.; Miniello, G.; My, S.; Nuzzo, S.; Pompili, A.; Pugliese, G.; Radogna, R.; Ranieri, A.; Selvaggi, G.; Sharma, A.; Silvestris, L.; Venditti, R.; Verwilligen, P.; Abbiendi, G.; Battilana, C.; Bonacorsi, D.; Braibant-Giacomelli, S.; Brigliadori, L.; Campanini, R.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Chhibra, S. S.; Codispoti, G.; Cuffiani, M.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Grandi, C.; Guiducci, L.; Marcellini, S.; Masetti, G.; Montanari, A.; Navarria, F. L.; Perrotta, A.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Tosi, N.; Albergo, S.; Costa, S.; Di Mattia, A.; Giordano, F.; Potenza, R.; Tricomi, A.; Tuve, C.; Barbagli, G.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Lenzi, P.; Meschini, M.; Paoletti, S.; Russo, L.; Sguazzoni, G.; Strom, D.; Viliani, L.; Benussi, L.; Bianco, S.; Fabbri, F.; Piccolo, D.; Primavera, F.; Calvelli, V.; Ferro, F.; Monge, M. R.; Robutti, E.; Tosi, S.; Brianza, L.; Brivio, F.; Ciriolo, V.; Dinardo, M. E.; Fiorendi, S.; Gennai, S.; Ghezzi, A.; Govoni, P.; Malberti, M.; Malvezzi, S.; Manzoni, R. A.; Menasce, D.; Moroni, L.; Paganoni, M.; Pedrini, D.; Pigazzini, S.; Ragazzi, S.; de Fatis, T. Tabarelli; Buontempo, S.; Cavallo, N.; De Nardo, G.; Di Guida, S.; Fabozzi, F.; Fienga, F.; Iorio, A. O. M.; Lista, L.; Meola, S.; Paolucci, P.; Sciacca, C.; Thyssen, F.; Azzi, P.; Bacchetta, N.; Benato, L.; Bisello, D.; Boletti, A.; Carlin, R.; De Oliveira, A. Carvalho Antunes; Checchia, P.; Dall'Osso, M.; De Castro Manzano, P.; Dorigo, T.; Dosselli, U.; Gasparini, F.; Gasparini, U.; Gozzelino, A.; Lacaprara, S.; Margoni, M.; Meneguzzo, A. T.; Pazzini, J.; Pozzobon, N.; Ronchese, P.; Simonetto, F.; Torassa, E.; Zanetti, M.; Zotto, P.; Zumerle, G.; Braghieri, A.; Fallavollita, F.; Magnani, A.; Montagna, P.; Ratti, S. P.; Re, V.; Riccardi, C.; Salvini, P.; Vai, I.; Vitulo, P.; Solestizi, L. Alunni; Bilei, G. M.; Ciangottini, D.; Fanò, L.; Lariccia, P.; Leonardi, R.; Mantovani, G.; Mariani, V.; Menichelli, M.; Saha, A.; Santocchia, A.; Androsov, K.; Azzurri, P.; Bagliesi, G.; Bernardini, J.; Boccali, T.; Castaldi, R.; Ciocci, M. A.; Dell'Orso, R.; Donato, S.; Fedi, G.; Giassi, A.; Grippo, M. T.; Ligabue, F.; Lomtadze, T.; Martini, L.; Messineo, A.; Palla, F.; Rizzi, A.; Savoy-Navarro, A.; Spagnolo, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Barone, L.; Cavallari, F.; Cipriani, M.; Del Re, D.; Diemoz, M.; Gelli, S.; Longo, E.; Margaroli, F.; Marzocchi, B.; Meridiani, P.; Organtini, G.; Paramatti, R.; Preiato, F.; Rahatlou, S.; Rovelli, C.; Santanastasio, F.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bartosik, N.; Bellan, R.; Biino, C.; Cartiglia, N.; Cenna, F.; Costa, M.; Covarelli, R.; Degano, A.; Demaria, N.; Finco, L.; Kiani, B.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Monteil, E.; Monteno, M.; Obertino, M. M.; Pacher, L.; Pastrone, N.; Pelliccioni, M.; Pinna Angioni, G. L.; Ravera, F.; Romero, A.; Ruspa, M.; Sacchi, R.; Shchelina, K.; Sola, V.; Solano, A.; Staiano, A.; Traczyk, P.; Belforte, S.; Casarsa, M.; Cossutti, F.; Della Ricca, G.; Zanetti, A.; Kim, D. H.; Kim, G. N.; Kim, M. S.; Lee, S.; Lee, S. W.; Oh, Y. D.; Sekmen, S.; Son, D. C.; Yang, Y. C.; Lee, A.; Kim, H.; Brochero Cifuentes, J. A.; Kim, T. J.; Cho, S.; Choi, S.; Go, Y.; Gyun, D.; Ha, S.; Hong, B.; Jo, Y.; Kim, Y.; Lee, K.; Lee, K. S.; Lee, S.; Lim, J.; Park, S. K.; Roh, Y.; Almond, J.; Kim, J.; Lee, H.; Oh, S. B.; Radburn-Smith, B. C.; Seo, S. h.; Yang, U. K.; Yoo, H. D.; Yu, G. B.; Choi, M.; Kim, H.; Kim, J. H.; Lee, J. S. H.; Park, I. C.; Ryu, G.; Ryu, M. S.; Choi, Y.; Goh, J.; Hwang, C.; Lee, J.; Yu, I.; Dudenas, V.; Juodagalvis, A.; Vaitkus, J.; Ahmed, I.; Ibrahim, Z. A.; Ali, M. A. B. Md; Mohamad Idris, F.; Abdullah, W. A. T. Wan; Yusli, M. N.; Zolkapli, Z.; Castilla-Valdez, H.; De La Cruz-Burelo, E.; Heredia-De La Cruz, I.; Hernandez-Almada, A.; Lopez-Fernandez, R.; Magaña Villalba, R.; Mejia Guisao, J.; Sanchez-Hernandez, A.; Carrillo Moreno, S.; Oropeza Barrera, C.; Vazquez Valencia, F.; Carpinteyro, S.; Pedraza, I.; Salazar Ibarguen, H. A.; Uribe Estrada, C.; Morelos Pineda, A.; Krofcheck, D.; Butler, P. H.; Ahmad, A.; Ahmad, M.; Hassan, Q.; Hoorani, H. R.; Khan, W. A.; Saddique, A.; Shah, M. A.; Shoaib, M.; Waqas, M.; Bialkowska, H.; Bluj, M.; Boimska, B.; Frueboes, T.; Górski, M.; Kazana, M.; Nawrocki, K.; Romanowska-Rybinska, K.; Szleper, M.; Zalewski, P.; Bunkowski, K.; Byszuk, A.; Doroba, K.; Kalinowski, A.; Konecki, M.; Krolikowski, J.; Misiura, M.; Olszewski, M.; Walczak, M.; Bargassa, P.; Da Cruz E. Silva, C. Beirão; Calpas, B.; Di Francesco, A.; Faccioli, P.; Gallinaro, M.; Hollar, J.; Leonardo, N.; Lloret Iglesias, L.; Nemallapudi, M. V.; Seixas, J.; Toldaiev, O.; Vadruccio, D.; Varela, J.; Afanasiev, S.; Bunin, P.; Gavrilenko, M.; Golutvin, I.; Gorbunov, I.; Kamenev, A.; Karjavin, V.; Lanev, A.; Malakhov, A.; Matveev, V.; Palichik, V.; Perelygin, V.; Shmatov, S.; Shulha, S.; Skatchkov, N.; Smirnov, V.; Voytishin, N.; Zarubin, A.; Chtchipounov, L.; Golovtsov, V.; Ivanov, Y.; Kim, V.; Kuznetsova, E.; Murzin, V.; Oreshkin, V.; Sulimov, V.; Vorobyev, A.; Andreev, Yu.; Dermenev, A.; Gninenko, S.; Golubev, N.; Karneyeu, A.; Kirsanov, M.; Krasnikov, N.; Pashenkov, A.; Tlisov, D.; Toropin, A.; Epshteyn, V.; Gavrilov, V.; Lychkovskaya, N.; Popov, V.; Pozdnyakov, I.; Safronov, G.; Spiridonov, A.; Toms, M.; Vlasov, E.; Zhokin, A.; Aushev, T.; Bylinkin, A.; Danilov, M.; Polikarpov, S.; Tarkovskii, E.; Andreev, V.; Azarkin, M.; Dremin, I.; Kirakosyan, M.; Leonidov, A.; Terkulov, A.; Baskakov, A.; Belyaev, A.; Boos, E.; Ershov, A.; Gribushin, A.; Khein, L.; Klyukhin, V.; Kodolova, O.; Lokhtin, I.; Lukina, O.; Miagkov, I.; Obraztsov, S.; Petrushanko, S.; Savrin, V.; Snigirev, A.; Blinov, V.; Skovpen, Y.; Shtol, D.; Azhgirey, I.; Bayshev, I.; Bitioukov, S.; Elumakhov, D.; Kachanov, V.; Kalinin, A.; Konstantinov, D.; Krychkine, V.; Petrov, V.; Ryutin, R.; Sobol, A.; Troshin, S.; Tyurin, N.; Uzunian, A.; Volkov, A.; Adzic, P.; Cirkovic, P.; Devetak, D.; Dordevic, M.; Milosevic, J.; Rekovic, V.; Alcaraz Maestre, J.; Barrio Luna, M.; Calvo, E.; Cerrada, M.; Chamizo Llatas, M.; Colino, N.; De La Cruz, B.; Delgado Peris, A.; Del Valle, A. Escalante; Fernandez Bedoya, C.; Fernández Ramos, J. P.; Flix, J.; Fouz, M. C.; Garcia-Abia, P.; Gonzalez Lopez, O.; Lopez, S. Goy; Hernandez, J. M.; Josa, M. I.; De Martino, E. Navarro; Pérez-Calero Yzquierdo, A.; Puerta Pelayo, J.; Quintario Olmeda, A.; Redondo, I.; Romero, L.; Soares, M. S.; Albajar, C.; de Trocóniz, J. F.; Missiroli, M.; Moran, D.; Cuevas, J.; Fernandez Menendez, J.; Gonzalez Caballero, I.; González Fernández, J. R.; Palencia Cortezon, E.; Sanchez Cruz, S.; Suárez Andrés, I.; Vischia, P.; Vizan Garcia, J. M.; Cabrillo, I. J.; Calderon, A.; Curras, E.; Fernandez, M.; Garcia-Ferrero, J.; Gomez, G.; Lopez Virto, A.; Marco, J.; Martinez Rivero, C.; Matorras, F.; Piedra Gomez, J.; Rodrigo, T.; Ruiz-Jimeno, A.; Scodellaro, L.; Trevisani, N.; Vila, I.; Vilar Cortabitarte, R.; Abbaneo, D.; Auffray, E.; Auzinger, G.; Baillon, P.; Ball, A. H.; Barney, D.; Bloch, P.; Bocci, A.; Botta, C.; Camporesi, T.; Castello, R.; Cepeda, M.; Cerminara, G.; Chen, Y.; d'Enterria, D.; Dabrowski, A.; Daponte, V.; David, A.; De Gruttola, M.; De Roeck, A.; Di Marco, E.; Dobson, M.; Dorney, B.; du Pree, T.; Duggan, D.; Dünser, M.; Dupont, N.; Elliott-Peisert, A.; Everaerts, P.; Fartoukh, S.; Franzoni, G.; Fulcher, J.; Funk, W.; Gigi, D.; Gill, K.; Girone, M.; Glege, F.; Gulhan, D.; Gundacker, S.; Guthoff, M.; Harris, P.; Hegeman, J.; Innocente, V.; Janot, P.; Kieseler, J.; Kirschenmann, H.; Knünz, V.; Kornmayer, A.; Kortelainen, M. J.; Kousouris, K.; Krammer, M.; Lange, C.; Lecoq, P.; Lourenço, C.; Lucchini, M. T.; Malgeri, L.; Mannelli, M.; Martelli, A.; Meijers, F.; Merlin, J. A.; Mersi, S.; Meschi, E.; Milenovic, P.; Moortgat, F.; Morovic, S.; Mulders, M.; Neugebauer, H.; Orfanelli, S.; Orsini, L.; Pape, L.; Perez, E.; Peruzzi, M.; Petrilli, A.; Petrucciani, G.; Pfeiffer, A.; Pierini, M.; Racz, A.; Reis, T.; Rolandi, G.; Rovere, M.; Sakulin, H.; Sauvan, J. B.; Schäfer, C.; Schwick, C.; Seidel, M.; Sharma, A.; Silva, P.; Sphicas, P.; Steggemann, J.; Stoye, M.; Takahashi, Y.; Tosi, M.; Treille, D.; Triossi, A.; Tsirou, A.; Veckalns, V.; Veres, G. I.; Verweij, M.; Wardle, N.; Wöhri, H. K.; Zagozdzinska, A.; Zeuner, W. D.; Bertl, W.; Deiters, K.; Erdmann, W.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; Kotlinski, D.; Langenegger, U.; Rohe, T.; Wiederkehr, S. A.; Bachmair, F.; Bäni, L.; Bianchini, L.; Casal, B.; Dissertori, G.; Dittmar, M.; Donegà, M.; Grab, C.; Heidegger, C.; Hits, D.; Hoss, J.; Kasieczka, G.; Lustermann, W.; Mangano, B.; Marionneau, M.; del Arbol, P. Martinez Ruiz; Masciovecchio, M.; Meinhard, M. T.; Meister, D.; Micheli, F.; Musella, P.; Nessi-Tedaldi, F.; Pandolfi, F.; Pata, J.; Pauss, F.; Perrin, G.; Perrozzi, L.; Quittnat, M.; Rossini, M.; Schönenberger, M.; Starodumov, A.; Tavolaro, V. R.; Theofilatos, K.; Wallny, R.; Aarrestad, T. K.; Amsler, C.; Caminada, L.; Canelli, M. F.; De Cosa, A.; Galloni, C.; Hinzmann, A.; Hreus, T.; Kilminster, B.; Ngadiuba, J.; Pinna, D.; Rauco, G.; Robmann, P.; Salerno, D.; Seitz, C.; Yang, Y.; Zucchetta, A.; Candelise, V.; Doan, T. H.; Jain, Sh.; Khurana, R.; Konyushikhin, M.; Kuo, C. M.; Lin, W.; Pozdnyakov, A.; Yu, S. S.; Kumar, Arun; Chang, P.; Chang, Y. H.; Chao, Y.; Chen, K. F.; Chen, P. H.; Fiori, F.; Hou, W.-S.; Hsiung, Y.; Liu, Y. F.; Lu, R.-S.; Miñano Moya, M.; Paganis, E.; Psallidas, A.; Tsai, J. f.; Asavapibhop, B.; Singh, G.; Srimanobhas, N.; Suwonjandee, N.; Adiguzel, A.; Cerci, S.; Damarseckin, S.; Demiroglu, Z. S.; Dozen, C.; Dumanoglu, I.; Girgis, S.; Gokbulut, G.; Guler, Y.; Hos, I.; Kangal, E. E.; Kara, O.; Topaksu, A. Kayis; Kiminsu, U.; Oglakci, M.; Onengut, G.; Ozdemir, K.; Cerci, D. Sunar; Topakli, H.; Turkcapar, S.; Zorbakir, I. S.; Zorbilmez, C.; Bilin, B.; Bilmis, S.; Isildak, B.; Karapinar, G.; Yalvac, M.; Zeyrek, M.; Gülmez, E.; Kaya, M.; Kaya, O.; Yetkin, E. A.; Yetkin, T.; Cakir, A.; Cankocak, K.; Sen, S.; Grynyov, B.; Levchuk, L.; Sorokin, P.; Aggleton, R.; Ball, F.; Beck, L.; Brooke, J. J.; Burns, D.; Clement, E.; Cussans, D.; Flacher, H.; Goldstein, J.; Grimes, M.; Heath, G. P.; Heath, H. F.; Jacob, J.; Kreczko, L.; Lucas, C.; Newbold, D. M.; Paramesvaran, S.; Poll, A.; Sakuma, T.; Seif El Nasr-storey, S.; Smith, D.; Smith, V. J.; Bell, K. W.; Belyaev, A.; Brew, C.; Brown, R. M.; Calligaris, L.; Cieri, D.; Cockerill, D. J. A.; Coughlan, J. A.; Harder, K.; Harper, S.; Olaiya, E.; Petyt, D.; Shepherd-Themistocleous, C. H.; Thea, A.; Tomalin, I. R.; Williams, T.; Baber, M.; Bainbridge, R.; Buchmuller, O.; Bundock, A.; Burton, D.; Casasso, S.; Citron, M.; Colling, D.; Corpe, L.; Dauncey, P.; Davies, G.; De Wit, A.; Della Negra, M.; Di Maria, R.; Dunne, P.; Elwood, A.; Futyan, D.; Haddad, Y.; Hall, G.; Iles, G.; James, T.; Lane, R.; Laner, C.; Lucas, R.; Lyons, L.; Magnan, A.-M.; Malik, S.; Mastrolorenzo, L.; Nash, J.; Nikitenko, A.; Pela, J.; Penning, B.; Pesaresi, M.; Raymond, D. M.; Richards, A.; Rose, A.; Scott, E.; Seez, C.; Summers, S.; Tapper, A.; Uchida, K.; Vazquez Acosta, M.; Virdee, T.; Wright, J.; Zenz, S. C.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Borzou, A.; Call, K.; Dittmann, J.; Hatakeyama, K.; Liu, H.; Pastika, N.; Bartek, R.; Dominguez, A.; Buccilli, A.; Cooper, S. I.; Henderson, C.; Rumerio, P.; West, C.; Arcaro, D.; Avetisyan, A.; Bose, T.; Gastler, D.; Rankin, D.; Richardson, C.; Rohlf, J.; Sulak, L.; Zou, D.; Benelli, G.; Cutts, D.; Garabedian, A.; Hakala, J.; Heintz, U.; Hogan, J. M.; Jesus, O.; Kwok, K. H. M.; Laird, E.; Landsberg, G.; Mao, Z.; Narain, M.; Piperov, S.; Sagir, S.; Spencer, E.; Syarif, R.; Breedon, R.; Burns, D.; De La Barca Sanchez, M. Calderon; Chauhan, S.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Erbacher, R.; Flores, C.; Funk, G.; Gardner, M.; Ko, W.; Lander, R.; Mclean, C.; Mulhearn, M.; Pellett, D.; Pilot, J.; Shalhout, S.; Shi, M.; Smith, J.; Squires, M.; Stolp, D.; Tos, K.; Tripathi, M.; Bachtis, M.; Bravo, C.; Cousins, R.; Dasgupta, A.; Florent, A.; Hauser, J.; Ignatenko, M.; Mccoll, N.; Saltzberg, D.; Schnaible, C.; Valuev, V.; Weber, M.; Bouvier, E.; Burt, K.; Clare, R.; Ellison, J.; Gary, J. W.; Ghiasi Shirazi, S. M. A.; Hanson, G.; Heilman, J.; Jandir, P.; Kennedy, E.; Lacroix, F.; Long, O. R.; Olmedo Negrete, M.; Paneva, M. I.; Shrinivas, A.; Si, W.; Wei, H.; Wimpenny, S.; Yates, B. R.; Branson, J. G.; Cerati, G. B.; Cittolin, S.; Derdzinski, M.; Gerosa, R.; Holzner, A.; Klein, D.; Krutelyov, V.; Letts, J.; Macneill, I.; Olivito, D.; Padhi, S.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Tadel, M.; Vartak, A.; Wasserbaech, S.; Welke, C.; Wood, J.; Würthwein, F.; Yagil, A.; Della Porta, G. Zevi; Amin, N.; Bhandari, R.; Bradmiller-Feld, J.; Campagnari, C.; Dishaw, A.; Dutta, V.; Franco Sevilla, M.; George, C.; Golf, F.; Gouskos, L.; Gran, J.; Heller, R.; Incandela, J.; Mullin, S. D.; Ovcharova, A.; Qu, H.; Richman, J.; Stuart, D.; Suarez, I.; Yoo, J.; Anderson, D.; Bendavid, J.; Bornheim, A.; Bunn, J.; Duarte, J.; Lawhorn, J. M.; Mott, A.; Newman, H. B.; Pena, C.; Spiropulu, M.; Vlimant, J. R.; Xie, S.; Zhu, R. Y.; Andrews, M. B.; Ferguson, T.; Paulini, M.; Russ, J.; Sun, M.; Vogel, H.; Vorobiev, I.; Weinberg, M.; Cumalat, J. P.; Ford, W. T.; Jensen, F.; Johnson, A.; Krohn, M.; Leontsinis, S.; Mulholland, T.; Stenson, K.; Wagner, S. R.; Alexander, J.; Chaves, J.; Chu, J.; Dittmer, S.; Mcdermott, K.; Mirman, N.; Kaufman, G. Nicolas; Patterson, J. R.; Rinkevicius, A.; Ryd, A.; Skinnari, L.; Soffi, L.; Tan, S. M.; Tao, Z.; Thom, J.; Tucker, J.; Wittich, P.; Zientek, M.; Winn, D.; Abdullin, S.; Albrow, M.; Apollinari, G.; Apresyan, A.; Banerjee, S.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Bolla, G.; Burkett, K.; Butler, J. N.; Cheung, H. W. K.; Chlebana, F.; Cihangir, S.; Cremonesi, M.; Elvira, V. D.; Fisk, I.; Freeman, J.; Gottschalk, E.; Gray, L.; Green, D.; Grünendahl, S.; Gutsche, O.; Hare, D.; Harris, R. M.; Hasegawa, S.; Hirschauer, J.; Hu, Z.; Jayatilaka, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Klima, B.; Kreis, B.; Lammel, S.; Linacre, J.; Lincoln, D.; Lipton, R.; Liu, M.; Liu, T.; De Sá, R. Lopes; Lykken, J.; Maeshima, K.; Magini, N.; Marraffino, J. M.; Maruyama, S.; Mason, D.; McBride, P.; Merkel, P.; Mrenna, S.; Nahn, S.; O'Dell, V.; Pedro, K.; Prokofyev, O.; Rakness, G.; Ristori, L.; Sexton-Kennedy, E.; Soha, A.; Spalding, W. J.; Spiegel, L.; Stoynev, S.; Strait, J.; Strobbe, N.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vernieri, C.; Verzocchi, M.; Vidal, R.; Wang, M.; Weber, H. A.; Whitbeck, A.; Wu, Y.; Acosta, D.; Avery, P.; Bortignon, P.; Bourilkov, D.; Brinkerhoff, A.; Carnes, A.; Carver, M.; Curry, D.; Das, S.; Field, R. D.; Furic, I. K.; Konigsberg, J.; Korytov, A.; Low, J. F.; Ma, P.; Matchev, K.; Mei, H.; Mitselmakher, G.; Rank, D.; Shchutska, L.; Sperka, D.; Thomas, L.; Wang, J.; Wang, S.; Yelton, J.; Linn, S.; Markowitz, P.; Martinez, G.; Rodriguez, J. L.; Ackert, A.; Adams, T.; Askew, A.; Bein, S.; Hagopian, S.; Hagopian, V.; Johnson, K. F.; Kolberg, T.; Perry, T.; Prosper, H.; Santra, A.; Yohay, R.; Baarmand, M. M.; Bhopatkar, V.; Colafranceschi, S.; Hohlmann, M.; Noonan, D.; Roy, T.; Yumiceva, F.; Adams, M. R.; Apanasevich, L.; Berry, D.; Betts, R. R.; Bucinskaite, I.; Cavanaugh, R.; Chen, X.; Evdokimov, O.; Gauthier, L.; Gerber, C. E.; Hofman, D. J.; Jung, K.; Sandoval Gonzalez, I. D.; Varelas, N.; Wang, H.; Wu, Z.; Zakaria, M.; Zhang, J.; Bilki, B.; Clarida, W.; Dilsiz, K.; Durgut, S.; Gandrajula, R. P.; Haytmyradov, M.; Khristenko, V.; Merlo, J.-P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Ogul, H.; Onel, Y.; Ozok, F.; Penzo, A.; Snyder, C.; Tiras, E.; Wetzel, J.; Yi, K.; Blumenfeld, B.; Cocoros, A.; Eminizer, N.; Fehling, D.; Feng, L.; Gritsan, A. V.; Maksimovic, P.; Roskes, J.; Sarica, U.; Swartz, M.; Xiao, M.; You, C.; Al-bataineh, A.; Baringer, P.; Bean, A.; Boren, S.; Bowen, J.; Castle, J.; Forthomme, L.; Kenny, R. P.; Khalil, S.; Kropivnitskaya, A.; Majumder, D.; Mcbrayer, W.; Murray, M.; Sanders, S.; Stringer, R.; Tapia Takaki, J. D.; Wang, Q.; Ivanov, A.; Kaadze, K.; Maravin, Y.; Mohammadi, A.; Saini, L. K.; Skhirtladze, N.; Toda, S.; Rebassoo, F.; Wright, D.; Anelli, C.; Baden, A.; Baron, O.; Belloni, A.; Calvert, B.; Eno, S. C.; Ferraioli, C.; Gomez, J. A.; Hadley, N. J.; Jabeen, S.; Jeng, G. Y.; Kellogg, R. G.; Kunkle, J.; Mignerey, A. C.; Ricci-Tam, F.; Shin, Y. H.; Skuja, A.; Tonjes, M. B.; Tonwar, S. C.; Abercrombie, D.; Allen, B.; Apyan, A.; Azzolini, V.; Barbieri, R.; Baty, A.; Bi, R.; Bierwagen, K.; Brandt, S.; Busza, W.; Cali, I. A.; D'Alfonso, M.; Demiragli, Z.; Gomez Ceballos, G.; Goncharov, M.; Hsu, D.; Iiyama, Y.; Innocenti, G. M.; Klute, M.; Kovalskyi, D.; Krajczar, K.; Lai, Y. S.; Lee, Y.-J.; Levin, A.; Luckey, P. D.; Maier, B.; Marini, A. C.; Mcginn, C.; Mironov, C.; Narayanan, S.; Niu, X.; Paus, C.; Roland, C.; Roland, G.; Salfeld-Nebgen, J.; Stephans, G. S. F.; Tatar, K.; Velicanu, D.; Wang, J.; Wang, T. W.; Wyslouch, B.; Benvenuti, A. C.; Chatterjee, R. M.; Evans, A.; Hansen, P.; Kalafut, S.; Kao, S. C.; Kubota, Y.; Lesko, Z.; Mans, J.; Nourbakhsh, S.; Ruckstuhl, N.; Rusack, R.; Tambe, N.; Turkewitz, J.; Acosta, J. G.; Oliveros, S.; Avdeeva, E.; Bloom, K.; Claes, D. R.; Fangmeier, C.; Gonzalez Suarez, R.; Kamalieddin, R.; Kravchenko, I.; Malta Rodrigues, A.; Monroy, J.; Siado, J. E.; Snow, G. R.; Stieger, B.; Alyari, M.; Dolen, J.; Godshalk, A.; Harrington, C.; Iashvili, I.; Kaisen, J.; Nguyen, D.; Parker, A.; Rappoccio, S.; Roozbahani, B.; Alverson, G.; Barberis, E.; Hortiangtham, A.; Massironi, A.; Morse, D. M.; Nash, D.; Orimoto, T.; De Lima, R. Teixeira; Trocino, D.; Wang, R.-J.; Wood, D.; Bhattacharya, S.; Charaf, O.; Hahn, K. A.; Kumar, A.; Mucia, N.; Odell, N.; Pollack, B.; Schmitt, M. H.; Sung, K.; Trovato, M.; Velasco, M.; Dev, N.; Hildreth, M.; Hurtado Anampa, K.; Jessop, C.; Karmgard, D. J.; Kellams, N.; Lannon, K.; Marinelli, N.; Meng, F.; Mueller, C.; Musienko, Y.; Planer, M.; Reinsvold, A.; Ruchti, R.; Rupprecht, N.; Smith, G.; Taroni, S.; Wayne, M.; Wolf, M.; Woodard, A.; Alimena, J.; Antonelli, L.; Bylsma, B.; Durkin, L. S.; Flowers, S.; Francis, B.; Hart, A.; Hill, C.; Ji, W.; Liu, B.; Luo, W.; Puigh, D.; Winer, B. L.; Wulsin, H. W.; Cooperstein, S.; Driga, O.; Elmer, P.; Hardenbrook, J.; Hebda, P.; Lange, D.; Luo, J.; Marlow, D.; Medvedeva, T.; Mei, K.; Ojalvo, I.; Olsen, J.; Palmer, C.; Piroué, P.; Stickland, D.; Svyatkovskiy, A.; Tully, C.; Malik, S.; Barker, A.; Barnes, V. E.; Folgueras, S.; Gutay, L.; Jha, M. K.; Jones, M.; Jung, A. W.; Khatiwada, A.; Miller, D. H.; Neumeister, N.; Schulte, J. F.; Shi, X.; Sun, J.; Wang, F.; Xie, W.; Parashar, N.; Stupak, J.; Adair, A.; Akgun, B.; Chen, Z.; Ecklund, K. M.; Geurts, F. J. M.; Guilbaud, M.; Li, W.; Michlin, B.; Northup, M.; Padley, B. P.; Roberts, J.; Rorie, J.; Tu, Z.; Zabel, J.; Betchart, B.; Bodek, A.; de Barbaro, P.; Demina, R.; Duh, Y. t.; Ferbel, T.; Galanti, M.; Garcia-Bellido, A.; Han, J.; Hindrichs, O.; Khukhunaishvili, A.; Lo, K. H.; Tan, P.; Verzetti, M.; Ciesielski, R.; Agapitos, A.; Chou, J. P.; Gershtein, Y.; Gómez Espinosa, T. A.; Halkiadakis, E.; Heindl, M.; Hughes, E.; Kaplan, S.; Kunnawalkam Elayavalli, R.; Kyriacou, S.; Lath, A.; Nash, K.; Osherson, M.; Saka, H.; Salur, S.; Schnetzer, S.; Sheffield, D.; Somalwar, S.; Stone, R.; Thomas, S.; Thomassen, P.; Walker, M.; Delannoy, A. G.; Foerster, M.; Heideman, J.; Riley, G.; Rose, K.; Spanier, S.; Thapa, K.; Bouhali, O.; Celik, A.; Dalchenko, M.; De Mattia, M.; Delgado, A.; Dildick, S.; Eusebi, R.; Gilmore, J.; Huang, T.; Juska, E.; Kamon, T.; Mueller, R.; Pakhotin, Y.; Patel, R.; Perloff, A.; Perniè, L.; Rathjens, D.; Safonov, A.; Tatarinov, A.; Ulmer, K. A.; Akchurin, N.; Damgov, J.; De Guio, F.; Dragoiu, C.; Dudero, P. R.; Faulkner, J.; Gurpinar, E.; Kunori, S.; Lamichhane, K.; Lee, S. W.; Libeiro, T.; Peltola, T.; Undleeb, S.; Volobouev, I.; Wang, Z.; Greene, S.; Gurrola, A.; Janjam, R.; Johns, W.; Maguire, C.; Melo, A.; Ni, H.; Sheldon, P.; Tuo, S.; Velkovska, J.; Xu, Q.; Arenton, M. W.; Barria, P.; Cox, B.; Goodell, J.; Hirosky, R.; Ledovskoy, A.; Li, H.; Neu, C.; Sinthuprasith, T.; Sun, X.; Wang, Y.; Wolfe, E.; Xia, F.; Clarke, C.; Harr, R.; Karchin, P. E.; Sturdy, J.; Zaleski, S.; Belknap, D. A.; Buchanan, J.; Caillol, C.; Dasu, S.; Dodd, L.; Duric, S.; Gomber, B.; Grothe, M.; Herndon, M.; Hervé, A.; Klabbers, P.; Lanaro, A.; Levine, A.; Long, K.; Loveless, R.; Pierro, G. A.; Polese, G.; Ruggles, T.; Savin, A.; Smith, N.; Smith, W. H.; Taylor, D.; Woods, N.

2018-03-01

Events with no charged particles produced between the two leading jets are studied in proton-proton collisions at √{s}=7 {TeV}. The jets were required to have transverse momentum pT ^{ {jet}}>40 {GeV} and pseudorapidity 1.50.2 {GeV} in the interval -1<η < 1 between the jets are observed in excess of calculations that assume no color-singlet exchange. The fraction of events with such a rapidity gap, amounting to 0.5-1% of the selected dijet sample, is measured as a function of the pT of the second-leading jet and of the rapidity separation between the jets. The data are compared to previous measurements at the Tevatron, and to perturbative quantum chromodynamics calculations based on the Balitsky-Fadin-Kuraev-Lipatov evolution equations, including different models of the non-perturbative gap survival probability.

Efficient process intensification of fine chemical production: a new classification tool for flow chemistry technologies

NARCIS (Netherlands)

Lexmond, A.S.; Roelands, C.P.M.; Graaff, M.P. de; Bassett, J.M.

2010-01-01

The fine chemicals and pharmaceuticals industry needs to innovate to beat international competition and resolve environmental issues. Process intensification by flow chemistry is the most promising route for this change, as it can reduce raw material and energy consumption, waste production, lead

Process Intensification Tools in the Small‐Scale Pharmaceutical Manufacturing of Small Molecules

DEFF Research Database (Denmark)

Mitic, Aleksandar; Gernaey, Krist V.

2015-01-01

of processes are in a state of change. However, it is important to note that not all processes can be intensified easily, such as slow chemical reactions, processes with solids, slurries, and on the like. This review summarizes applications of promising tools for achieving process intensification in the small......‐scale pharmaceutical manufacturing of so‐called small molecules. The focus is on microwave radiation, microreactors, ultrasounds, and meso‐scale tubular reactors....

A Simple Experiment for Teaching Process Intensification by Static Mixing in Chemical Reaction Engineering

Science.gov (United States)

Baz-Rodríguez, Sergio; Herrera-Soberanis, Natali; Rodríguez-Novelo, Miguel; Guillén-Francisc, Juana; Rocha-Uribe, José

2016-01-01

An experiment for teaching mixing intensification in reaction engineering is described. For this, a simple tubular reactor was constructed; helical static mixer elements were fabricated from stainless steel strips and inserted into the reactor. With and without the internals, the equipment operates as a static mixer reactor or a laminar flow…

KAJIAN INPUT ENERGI PADA BUDIDAYA PADI METODE SYSTEM OF RICE INTENSIFICATION Studies on Energy Input in System of Rice Intensification Method of Rice Cultivation

Directory of Open Access Journals (Sweden)

Bambang Purwantana

2012-05-01

Full Text Available System of Rice Intensification (SRI is a rice cultivation method that intensively control and manage macro and micro nutrients as well as irrigation. This paper quantifies and compares the energy uses of SRI and conventional rice cultiva- tion systems. The study was conducted at some SRI’s experimental plots in the districts of Sleman, Kulonprogo, and Bantul, the province of Yogyakarta. The calculation of the energy was based on the farmers’ work schedule, the time required for each operation, the number of laborers, machines, tools, fuel, and all materials and inputs used. The result shows that SRI method consumed 35% less energy to conventional rice cultivation. Energy inputs from seed, water, fertilizer and pesticide were significantly reduces. However, there was higher input of human energy due to compost- ing, land preparation and weeding operations. The specific energy of SRI method was 1.96 MJ ha-1 lower than conven- tional method of 4.43 MJ ha-1. In the SRI method, 56.2 % of energy consumed was classified as direct energy and 43.8% was indirect energy. The SRI method used 61.9 % of renewable energy and 38.1 % of non-renewable energy. The working efficiency in composting and weeding operations should be improved in perspective of machine and tools to reduce the use of human energy. ABSTRAK System of Rice Intensification (SRI, merupakan suatu metode budidaya padi secara intensif dengan pengendalian unsur-unsur hara makro dan mikro disertai pengendalian dan pengaturan kebutuhan air. Penelitian ini bertujuan untuk menganalisis penggunaan energi dan mengidentifikasi kemungkinan penghematan energi pada budidaya padi SRI. Pe- nelitian dilakukan di Kabupaten Sleman, Kulonprogo, dan Bantul, Propinsi Daerah Istimewa Yogyakarta. Pengamatan dilakukan pada plot-plot percobaan budidaya padi SRI dengan melakukan audit seluruh input energi selama proses budidaya dan dikomparasikan dengan input energi pada budidaya padi cara konvensional. Hasil

Ecological impacts of arable intensification in Europe.

Science.gov (United States)

Stoate, C; Boatman, N D; Borralho, R J; Carvalho, C R; de Snoo, G R; Eden, P

2001-12-01

Although arable landscapes have a long history, environmental problems have accelerated in recent decades. The effects of these changes are usually externalized, being greater for society as a whole than for the farms on which they operate, and incentives to correct them are therefore largely lacking. Arable landscapes are valued by society beyond the farming community, but increased mechanization and farm size, simplification of crop rotations, and loss of non-crop features, have led to a reduction in landscape diversity. Low intensity arable systems have evolved a characteristic and diverse fauna and flora, but development of high input, simplified arable systems has been associated with a decline in biodiversity. Arable intensification has resulted in loss of non-crop habitats and simplification of plant and animal communities within crops, with consequent disruption to food chains and declines in many farmland species. Abandonment of arable management has also led to the replacement of such wildlife with more common and widespread species. Soils have deteriorated as a result of erosion, compaction, loss of organic matter and contamination with pesticides, and in some areas, heavy metals. Impacts on water are closely related to those on soils as nutrient and pesticide pollution of water results from surface runoff and subsurface flow, often associated with soil particles, which themselves have economic and ecological impacts. Nitrates and some pesticides also enter groundwater following leaching from arable land. Greatest impacts are associated with simplified, high input arable systems. Intensification of arable farming has been associated with pollution of air by pesticides, NO2 and CO2, while the loss of soil organic matter has reduced the system's capacity for carbon sequestration. International trade contributes to global climate change through long distance transport of arable inputs and products. The EU Rural Development Regulation (1257/99) provides an

Evaluating strategies for sustainable intensification of U.S. agriculture through the Long-Term Agroecosystem Research network

Science.gov (United States)

Sustainable intensification is an emerging model for agriculture designed to reconcile accelerating global demand for agricultural products with long-term environmental stewardship. Defined here as increasing agricultural production while maintaining or improving environmental quality, sustainable i...

Stable Low Cloud Phase II: Nocturnal Event Study

Science.gov (United States)

Bauman, William H., III; Barrett, Joe, III

2007-01-01

This report describes the work done by the Applied Meteorology Unit (AMU) in developing a database of nights that experienced rapid (formation in a stable atmosphere, resulting in ceilings at the Shuttle Landing Facility (TTS) that violated Space Shuttle Flight Rules (FR). This work is the second phase of a similar AMU task that examined the same phenomena during the day. In the first phase of this work, the meteorological conditions favoring the rapid formation of low ceilings include the presence of any inversion below 8000 ft, high relative humidity (RH) beneath the inversion and a clockwise turning of the winds from the surface to the middle troposphere (-15000 ft). The AMU compared and contrasted the atmospheric and thermodynamic conditions between nights with rapid low ceiling formation and nights with low ceilings resulting from other mechanisms. The AMU found that there was little to discern between the rapidly-forming ceiling nights and other low ceiling nights at TTS. When a rapid development occurred, the average RH below the inversions was 87% while non-events had an average RH of 79%. One key parameter appeared to be the vertical wind profile in the Cape Canaveral, FL radiosonde (XMR) sounding. Eighty-three percent of the rapid development events had veering winds with height from the surface to the middle troposphere (-15,000 ft) while 61% of the non-events had veering winds with height. Veering winds indicate a warm-advection regime, which supports large-scale rising motion and ultimately cloud formation in a moist environment. However, only six of the nights (out of 86 events examined) with low cloud ceilings had an occurrence of rapidly developing ceilings. Since only 7% rapid development events were observed in this dataset, it is likely that rapid low cloud development is not a common occurrence during the night, or at least not as common as during the day. In the AMU work on the daytime rapid low cloud development (Case and Wheeler 2005), nearly

Biotechnological intensification of biogas production

Energy Technology Data Exchange (ETDEWEB)

Bagi, Z.; Acs, N.; Balint, B.; Horvath, L.; Dobo, K.; Perei, K.R.; Rakhely, G.; Kovacs, K.L. [Szeged Univ. (Hungary). Dept. of Biotechnology; Hungarian Academy of Sciences, Szeged (Hungary). Inst. of Biophysics

2007-08-15

The importance of syntrophic relationships among microorganisms participating in biogas formation has been emphasized, and the regulatory role of in situ hydrogen production has been recognized. It was assumed that the availability of hydrogen may be a limiting factor for hydrogenotrophic methanogens. This hypothesis was tested under laboratory and field conditions by adding a mesophilic (Enterobacter cloacae) or thermophilic hydrogen-producing (Caldicellulosyruptor saccharolyticus) strain to natural biogas-producing consortia. The substrates were waste water sludge, dried plant biomass from Jerusalem artichoke, and pig manure. In all cases, a significant intensification of biogas production was observed. The composition of the generated biogas did not noticeably change. In addition to being a good hydrogen producer, C. saccharolyticus has cellulolytic activity; hence, it is particularly suitable when cellulose-containing biomass is fermented. The process was tested in a 5-m{sup 3} thermophilic biogas digester using pig manure slurry as a substrate. Biogas formation increased at least 160-170% upon addition of the hydrogen-producing bacteria as compared to the biogas production of the spontaneously formed microbial consortium. Using the hydrogenase-minus control strain provided evidence that the observed enhancement was due to interspecies hydrogen transfer. The on-going presence of C. saccharolyticus was demonstrated after several months of semicontinuous operation. (orig.)

Understanding wicked problems and organized irresponsibility: challenges for governing the sustainable intensification of chicken meat production

NARCIS (Netherlands)

Bueren, E.M.; Lammerts Van Bueren, E.; Zijpp, van der A.J.

2014-01-01

Framing sustainable intensification as a wicked problem reveals how inherent trade-offs and resulting uncertainty and ambiguity block integrated problem solving as promoted by sustainable chain management approaches to production and consumption. The fragmented institutional set-up of the chains

Impact of an intense water column mixing (0-1500 m) on prokaryotic diversity and activities during an open-ocean convection event in the NW Mediterranean Sea.

Science.gov (United States)

Severin, Tatiana; Sauret, Caroline; Boutrif, Mehdi; Duhaut, Thomas; Kessouri, Fayçal; Oriol, Louise; Caparros, Jocelyne; Pujo-Pay, Mireille; Durrieu de Madron, Xavier; Garel, Marc; Tamburini, Christian; Conan, Pascal; Ghiglione, Jean-François

2016-12-01

Open-ocean convection is a fundamental process for thermohaline circulation and biogeochemical cycles that causes spectacular mixing of the water column. Here, we tested how much the depth-stratified prokaryotic communities were influenced by such an event, and also by the following re-stratification. The deep convection event (0-1500 m) that occurred in winter 2010-2011 in the NW Mediterranean Sea resulted in a homogenization of the prokaryotic communities over the entire convective cell, resulting in the predominance of typical surface Bacteria, such as Oceanospirillale and Flavobacteriales. Statistical analysis together with numerical simulation of vertical homogenization evidenced that physical turbulence only was not enough to explain the new distribution of the communities, but acted in synergy with other parameters such as exported particulate and dissolved organic matters. The convection also stimulated prokaryotic abundance (+21%) and heterotrophic production (+43%) over the 0-1500 m convective cell, and resulted in a decline of cell-specific extracellular enzymatic activities (-67%), thus suggesting an intensification of the labile organic matter turnover during the event. The rapid re-stratification of the prokaryotic diversity and activities in the intermediate layer 5 days after the intense mixing indicated a marked resilience of the communities, apart from the residual deep mixed water patch. © 2016 The Authors. Environmental Microbiology published by Society for Applied Microbiology and John Wiley & Sons Ltd.

Clinical inertia and its impact on treatment intensification in people with type 2 diabetes mellitus.

Science.gov (United States)

Reach, G; Pechtner, V; Gentilella, R; Corcos, A; Ceriello, A

2017-12-01

Many people with type 2 diabetes mellitus (T2DM) fail to achieve glycaemic control promptly after diagnosis and do not receive timely treatment intensification. This may be in part due to 'clinical inertia', defined as the failure of healthcare providers to initiate or intensify therapy when indicated. Physician-, patient- and healthcare-system-related factors all contribute to clinical inertia. However, decisions that appear to be clinical inertia may, in fact, be only 'apparent' clinical inertia and may reflect good clinical practice on behalf of the physician for a specific patient. Delay in treatment intensification can happen at all stages of treatment for people with T2DM, including prescription of lifestyle changes after diagnosis, introduction of pharmacological therapy, use of combination therapy where needed and initiation of insulin. Clinical inertia may contribute to people with T2DM living with suboptimal glycaemic control for many years, with dramatic consequences for the patient in terms of quality of life, morbidity and mortality, and for public health because of the huge costs associated with uncontrolled T2DM. Because multiple factors can lead to clinical inertia, potential solutions most likely require a combination of approaches involving fundamental changes in medical care. These could include the adoption of a person-centred model of care to account for the complex considerations influencing treatment decisions by patients and physicians. Better patient education about the progressive nature of T2DM and the risks inherent in long-term poor glycaemic control may also reinforce the need for regular treatment reviews, with intensification when required. Copyright © 2017 The Authors. Published by Elsevier Masson SAS.. All rights reserved.

Nursing in Times of Neoliberal Change: An Ethnographic Study of Nurses’ Experiences of Work Intensification

Directory of Open Access Journals (Sweden)

Rebecca Selberg

2013-05-01

Full Text Available Through an ethnographic study of nurses’ experiences of work intensification, this article shows how nurses respond to and act upon neoliberal transformations of work. The article identifies and explores those transformations considered by the informants, nurses working in public sector hospital wards, as central to changing conditions of work and experiences of work intensifications. It further analyzes nurses’ responses toward these transformations and locates these responses within a particular form of femininity evolving from rationalities of care, nurses’ conditions within the organization, and classed and gendered experiences of care work. The article illustrates that in times of neoliberal change and public sector resource depletion, nurses respond to women’s traditional caring responsibilities as well as to professional commitments and cover for the organization. Maintaining the level of frontline service is contingent on increased exploitation and performance control of ward nurses, and their ability and willingness to sacrifice their own time and health for the sake of their patients. The article argues that in the case of ward nurses in the Swedish public sector, work intensification is a multilayered process propelled by three intersecting forces: austerity ideology linked to the neoliberal transformation of the welfare state and public sector retrenchment; explicit care rationalities impelled by aspirations of the nursing profession to establish, render visible, and expand the nursing field both in relation to the medical profession and in relation to so-called unskilled care work performed by assistant nurses and auxiliaries; and the progressive aspect of New Public Management, which challenges the power and authority of the professions and contributes to strengthening the positions of clients and patients.

Estimating the potential intensification of global grazing systems based on climate adjusted yield gap analysis

Science.gov (United States)

Sheehan, J. J.

2016-12-01

We report here a first-of-its-kind analysis of the potential for intensification of global grazing systems. Intensification is calculated using the statistical yield gap methodology developed previously by others (Mueller et al 2012 and Licker et al 2010) for global crop systems. Yield gaps are estimated by binning global pasture land area into 100 equal area sized bins of similar climate (defined by ranges of rainfall and growing degree days). Within each bin, grid cells of pastureland are ranked from lowest to highest productivity. The global intensification potential is defined as the sum of global production across all bins at a given percentile ranking (e.g. performance at the 90th percentile) divided by the total current global production. The previous yield gap studies focused on crop systems because productivity data on these systems is readily available. Nevertheless, global crop land represents only one-third of total global agricultural land, while pasture systems account for the remaining two-thirds. Thus, it is critical to conduct the same kind of analysis on what is the largest human use of land on the planet—pasture systems. In 2013, Herrero et al announced the completion of a geospatial data set that augmented the animal census data with data and modeling about production systems and overall food productivity (Herrero et al, PNAS 2013). With this data set, it is now possible to apply yield gap analysis to global pasture systems. We used the Herrero et al data set to evaluate yield gaps for meat and milk production from pasture based systems for cattle, sheep and goats. The figure included with this abstract shows the intensification potential for kcal per hectare per year of meat and milk from global cattle, sheep and goats as a function of increasing levels of performance. Performance is measured as the productivity achieved at a given ranked percentile within each bin.We find that if all pasture land were raised to their 90th percentile of

Measurement of the shape of the boson rapidity distribution for $p\\bar{p} \\rightarrow Z/\\gamma^{*} \\rightarrow e^{+}e^{-} + X$ events produced at $\\sqrt{s} =1.96$ TeV

Energy Technology Data Exchange (ETDEWEB)

Ding, Pengfei [Univ. of Manchester (United Kingdom)

2013-09-01

The measurement of the shape of the boson rapidity distribution for p $\\bar{p}$ → Z/γ* → e⁺e^- + X events at a center-of-mass energy of 1.96 TeV is presented in this thesis. Data, with an integrated luminosity of L = 9.86 fb^-1, collected with the D0 detector during the whole RunII data taking period of the Fermilab Tevatron p$\\bar{p}$ collider has been used. The measurement is made for events with electron-positron mass 66 < M_ee < 111 GeV. The current result gives the best precision of the boson rapidity shape at the Tevatron. It signi cantly reduces the uncertainty in the boson rapidity range |y| > 2:3. Predictions of Next-to- Leading-Order (NLO) QCD theory with CTEQ and MSTW parton distribution functions are found to agree well with the data over the full rapidity range.

Integrated database for rapid mass movements in Norway

Directory of Open Access Journals (Sweden)

C. Jaedicke

2009-03-01

Full Text Available Rapid gravitational slope mass movements include all kinds of short term relocation of geological material, snow or ice. Traditionally, information about such events is collected separately in different databases covering selected geographical regions and types of movement. In Norway the terrain is susceptible to all types of rapid gravitational slope mass movements ranging from single rocks hitting roads and houses to large snow avalanches and rock slides where entire mountainsides collapse into fjords creating flood waves and endangering large areas. In addition, quick clay slides occur in desalinated marine sediments in South Eastern and Mid Norway. For the authorities and inhabitants of endangered areas, the type of threat is of minor importance and mitigation measures have to consider several types of rapid mass movements simultaneously.

An integrated national database for all types of rapid mass movements built around individual events has been established. Only three data entries are mandatory: time, location and type of movement. The remaining optional parameters enable recording of detailed information about the terrain, materials involved and damages caused. Pictures, movies and other documentation can be uploaded into the database. A web-based graphical user interface has been developed allowing new events to be entered, as well as editing and querying for all events. An integration of the database into a GIS system is currently under development.

Datasets from various national sources like the road authorities and the Geological Survey of Norway were imported into the database. Today, the database contains 33 000 rapid mass movement events from the last five hundred years covering the entire country. A first analysis of the data shows that the most frequent type of recorded rapid mass movement is rock slides and snow avalanches followed by debris slides in third place. Most events are recorded in the steep fjord

A review of engineering aspects of intensification of chemical synthesis using ultrasound.

Science.gov (United States)

Sancheti, Sonam V; Gogate, Parag R

2017-05-01

Cavitation generated using ultrasound can enhance the rates of several chemical reactions giving better selectivity based on the physical and chemical effects. The present review focuses on overview of the different reactions that can be intensified using ultrasound followed by the discussion on the chemical kinetics for ultrasound assisted reactions, engineering aspects related to reactor designs and effect of operating parameters on the degree of intensification obtained for chemical synthesis. The cavitational effects in terms of magnitudes of collapse temperatures and collapse pressure, number of free radicals generated and extent of turbulence are strongly dependent on the operating parameters such as ultrasonic power, frequency, duty cycle, temperature as well as physicochemical parameters of liquid medium which controls the inception of cavitation. Guidelines have been presented for the optimum selection based on the critical analysis of the existing literature so that maximum process intensification benefits can be obtained. Different reactor designs have also been analyzed with guidelines for efficient scale up of the sonochemical reactor, which would be dependent on the type of reaction, controlling mechanism of reaction, catalyst and activation energy requirements. Overall, it has been established that sonochemistry offers considerable potential for green and sustainable processing and efficient scale up procedures are required so as to harness the effects at actual commercial level. Copyright © 2016 Elsevier B.V. All rights reserved.

Study of the underlying event at forward rapidity in pp collisions at $ \\sqrt{s}=0.9,2.76,\\;\\mathrm{and}\\;7\\;\\mathrm{TeV} $

Energy Technology Data Exchange (ETDEWEB)

Chatrchyan, S.; Khachatryan, V.; Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Aguilo, E.; Bergauer, T.; Dragicevic, M.; Erö, J.; Fabjan, C.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Hörmann, N.; Hrubec, J.; Jeitler, M.; Kiesenhofer, W.; Knünz, V.; Krammer, M.; Krätschmer, I.; Liko, D.; Mikulec, I.; Pernicka, M.; Rabady, D.; Rahbaran, B.; Rohringer, C.; Rohringer, H.; Schöfbeck, R.; Strauss, J.; Taurok, A.; Waltenberger, W.; Wulz, C. -E.; Mossolov, V.; Shumeiko, N.; Suarez Gonzalez, J.; Alderweireldt, S.; Bansal, M.; Bansal, S.; Cornelis, T.; De Wolf, E. A.; Janssen, X.; Luyckx, S.; Mucibello, L.; Ochesanu, S.; Roland, B.; Rougny, R.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Van Spilbeeck, A.; Blekman, F.; Blyweert, S.; D’Hondt, J.; Gonzalez Suarez, R.; Kalogeropoulos, A.; Maes, M.; Olbrechts, A.; Tavernier, S.; Van Doninck, W.; Van Mulders, P.; Van Onsem, G. P.; Villella, I.; Clerbaux, B.; De Lentdecker, G.; Dero, V.; Gay, A. P. R.; Hreus, T.; Léonard, A.; Marage, P. E.; Mohammadi, A.; Reis, T.; Thomas, L.; Vander Velde, C.; Vanlaer, P.; Wang, J.; Adler, V.; Beernaert, K.; Cimmino, A.; Costantini, S.; Garcia, G.; Grunewald, M.; Klein, B.; Lellouch, J.; Marinov, A.; Mccartin, J.; Ocampo Rios, A. A.; Ryckbosch, D.; Sigamani, M.; Strobbe, N.; Thyssen, F.; Tytgat, M.; Walsh, S.; Yazgan, E.; Zaganidis, N.; Basegmez, S.; Bruno, G.; Castello, R.; Ceard, L.; Delaere, C.; du Pree, T.; Favart, D.; Forthomme, L.; Giammanco, A.; Hollar, J.; Lemaitre, V.; Liao, J.; Militaru, O.; Nuttens, C.; Pagano, D.; Pin, A.; Piotrzkowski, K.; Selvaggi, M.; Vizan Garcia, J. M.; Beliy, N.; Caebergs, T.; Daubie, E.; Hammad, G. H.; Alves, G. A.; Correa Martins Junior, M.; Martins, T.; Pol, M. E.; Souza, M. H. G.; Aldá Júnior, W. L.; Carvalho, W.; Chinellato, J.; Custódio, A.; Da Costa, E. M.; De Jesus Damiao, D.; De Oliveira Martins, C.; Fonseca De Souza, S.; Malbouisson, H.; Malek, M.; Matos Figueiredo, D.; Mundim, L.; Nogima, H.; Prado Da Silva, W. L.; Santoro, A.; Soares Jorge, L.; Sznajder, A.; Tonelli Manganote, E. J.; Vilela Pereira, A.; Anjos, T. S.; Bernardes, C. A.; Dias, F. A.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Lagana, C.; Marinho, F.; Mercadante, P. G.; Novaes, S. F.; Padula, Sandra S.; Genchev, V.; Iaydjiev, P.; Piperov, S.; Rodozov, M.; Stoykova, S.; Sultanov, G.; Tcholakov, V.; Trayanov, R.; Vutova, M.; Dimitrov, A.; Hadjiiska, R.; Kozhuharov, V.; Litov, L.; Pavlov, B.; Petkov, P.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Jiang, C. H.; Liang, D.; Liang, S.; Meng, X.; Tao, J.; Wang, J.; Wang, X.; Wang, Z.; Xiao, H.; Xu, M.; Zang, J.; Zhang, Z.; Asawatangtrakuldee, C.; Ban, Y.; Guo, Y.; Li, W.; Liu, S.; Mao, Y.; Qian, S. J.; Teng, H.; Wang, D.; Zhang, L.; Zou, W.; Avila, C.; Carrillo Montoya, C. A.; Gomez, J. P.; Gomez Moreno, B.; Osorio Oliveros, A. F.; Sanabria, J. 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L.; Ferri, F.; Ganjour, S.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Locci, E.; Malcles, J.; Millischer, L.; Nayak, A.; Rander, J.; Rosowsky, A.; Titov, M.; Baffioni, S.; Beaudette, F.; Benhabib, L.; Bianchini, L.; Bluj, M.; Busson, P.; Charlot, C.; Daci, N.; Dahms, T.; Dalchenko, M.; Dobrzynski, L.; Florent, A.; Granier de Cassagnac, R.; Haguenauer, M.; Miné, P.; Mironov, C.; Naranjo, I. N.; Nguyen, M.; Ochando, C.; Paganini, P.; Sabes, D.; Salerno, R.; Sirois, Y.; Veelken, C.; Zabi, A.; Agram, J. -L.; Andrea, J.; Bloch, D.; Bodin, D.; Brom, J. -M.; Chabert, E. C.; Collard, C.; Conte, E.; Drouhin, F.; Fontaine, J. -C.; Gelé, D.; Goerlach, U.; Juillot, P.; Le Bihan, A. -C.; Van Hove, P.; Beauceron, S.; Beaupere, N.; Bondu, O.; Boudoul, G.; Brochet, S.; Chasserat, J.; Chierici, R.; Contardo, D.; Depasse, P.; El Mamouni, H.; Fay, J.; Gascon, S.; Gouzevitch, M.; Ille, B.; Kurca, T.; Lethuillier, M.; Mirabito, L.; Perries, S.; Sgandurra, L.; Sordini, V.; Tschudi, Y.; Verdier, P.; Viret, S.; Tsamalaidze, Z.; Autermann, C.; Beranek, S.; Calpas, B.; Edelhoff, M.; Feld, L.; Heracleous, N.; Hindrichs, O.; Jussen, R.; Klein, K.; Merz, J.; Ostapchuk, A.; Perieanu, A.; Raupach, F.; Sammet, J.; Schael, S.; Sprenger, D.; Weber, H.; Wittmer, B.; Zhukov, V.; Ata, M.; Caudron, J.; Dietz-Laursonn, E.; Duchardt, D.; Erdmann, M.; Fischer, R.; Güth, A.; Hebbeker, T.; Heidemann, C.; Hoepfner, K.; Klingebiel, D.; Kreuzer, P.; Merschmeyer, M.; Meyer, A.; Olschewski, M.; Padeken, K.; Papacz, P.; Pieta, H.; Reithler, H.; Schmitz, S. A.; Sonnenschein, L.; Steggemann, J.; Teyssier, D.; Thüer, S.; Weber, M.; Bontenackels, M.; Cherepanov, V.; Erdogan, Y.; Flügge, G.; Geenen, H.; Geisler, M.; Haj Ahmad, W.; Hoehle, F.; Kargoll, B.; Kress, T.; Kuessel, Y.; Lingemann, J.; Nowack, A.; Nugent, I. M.; Perchalla, L.; Pooth, O.; Sauerland, P.; Stahl, A.; Aldaya Martin, M.; Asin, I.; Bartosik, N.; Behr, J.; Behrenhoff, W.; Behrens, U.; Bergholz, M.; Bethani, A.; Borras, K.; Burgmeier, A.; Cakir, A.; Calligaris, L.; Campbell, A.; Castro, E.; Costanza, F.; Dammann, D.; Diez Pardos, C.; Dorland, T.; Eckerlin, G.; Eckstein, D.; Flucke, G.; Geiser, A.; Glushkov, I.; Gunnellini, P.; Habib, S.; Hauk, J.; Hellwig, G.; Jung, H.; Kasemann, M.; Katsas, P.; Kleinwort, C.; Kluge, H.; Knutsson, A.; Krämer, M.; Krücker, D.; Kuznetsova, E.; Lange, W.; Leonard, J.; Lohmann, W.; Lutz, B.; Mankel, R.; Marfin, I.; Marienfeld, M.; Melzer-Pellmann, I. -A.; Meyer, A. B.; Mnich, J.; Mussgiller, A.; Naumann-Emme, S.; Novgorodova, O.; Nowak, F.; Olzem, J.; Perrey, H.; Petrukhin, A.; Pitzl, D.; Raspereza, A.; Ribeiro Cipriano, P. M.; Riedl, C.; Ron, E.; Rosin, M.; Salfeld-Nebgen, J.; Schmidt, R.; Schoerner-Sadenius, T.; Sen, N.; Spiridonov, A.; Stein, M.; Walsh, R.; Wissing, C.; Blobel, V.; Enderle, H.; Erfle, J.; Gebbert, U.; Görner, M.; Gosselink, M.; Haller, J.; Hermanns, T.; Höing, R. S.; Kaschube, K.; Kaussen, G.; Kirschenmann, H.; Klanner, R.; Lange, J.; Peiffer, T.; Pietsch, N.; Rathjens, D.; Sander, C.; Schettler, H.; Schleper, P.; Schlieckau, E.; Schmidt, A.; Schröder, M.; Schum, T.; Seidel, M.; Sibille, J.; Sola, V.; Stadie, H.; Steinbrück, G.; Thomsen, J.; Vanelderen, L.; Barth, C.; Baus, C.; Berger, J.; Böser, C.; Chwalek, T.; De Boer, W.; Descroix, A.; Dierlamm, A.; Feindt, M.; Guthoff, M.; Hackstein, C.; Hartmann, F.; Hauth, T.; Heinrich, M.; Held, H.; Hoffmann, K. H.; Husemann, U.; Katkov, I.; Komaragiri, J. R.; Lobelle Pardo, P.; Martschei, D.; Mueller, S.; Müller, Th.; Niegel, M.; Nürnberg, A.; Oberst, O.; Oehler, A.; Ott, J.; Quast, G.; Rabbertz, K.; Ratnikov, F.; Ratnikova, N.; Röcker, S.; Schilling, F. -P.; Schott, G.; Simonis, H. J.; Stober, F. M.; Troendle, D.; Ulrich, R.; Wagner-Kuhr, J.; Wayand, S.; Weiler, T.; Zeise, M.; Anagnostou, G.; Daskalakis, G.; Geralis, T.; Kesisoglou, S.; Kyriakis, A.; Loukas, D.; Markou, A.; Markou, C.; Ntomari, E.; Gouskos, L.; Mertzimekis, T. J.; Panagiotou, A.; Saoulidou, N.; Evangelou, I.; Foudas, C.; Kokkas, P.; Manthos, N.; Papadopoulos, I.; Bencze, G.; Hajdu, C.; Hidas, P.; Horvath, D.; Sikler, F.; Veszpremi, V.; Vesztergombi, G.; Zsigmond, A. J.; Beni, N.; Czellar, S.; Molnar, J.; Palinkas, J.; Szillasi, Z.; Karancsi, J.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Beri, S. B.; Bhatnagar, V.; Dhingra, N.; Gupta, R.; Kaur, M.; Mehta, M. Z.; Mittal, M.; Nishu, N.; Saini, L. K.; Sharma, A.; Singh, J. B.; Kumar, Ashok; Kumar, Arun; Ahuja, S.; Bhardwaj, A.; Choudhary, B. C.; Malhotra, S.; Naimuddin, M.; Ranjan, K.; Saxena, P.; Sharma, V.; Shivpuri, R. K.; Banerjee, S.; Bhattacharya, S.; Chatterjee, K.; Dutta, S.; Gomber, B.; Jain, Sa.; Jain, Sh.; Khurana, R.; Modak, A.; Mukherjee, S.; Roy, D.; Sarkar, S.; Sharan, M.; Abdulsalam, A.; Dutta, D.; Kailas, S.; Kumar, V.; Mohanty, A. K.; Pant, L. M.; Shukla, P.; Aziz, T.; Chatterjee, R. M.; Ganguly, S.; Guchait, M.; Gurtu, A.; Maity, M.; Majumder, G.; Mazumdar, K.; Mohanty, G. B.; Parida, B.; Sudhakar, K.; Wickramage, N.; Banerjee, S.; Dugad, S.; Arfaei, H.; Bakhshiansohi, H.; Etesami, S. M.; Fahim, A.; Hashemi, M.; Hesari, H.; Jafari, A.; Khakzad, M.; Mohammadi Najafabadi, M.; Paktinat Mehdiabadi, S.; Safarzadeh, B.; Zeinali, M.; Abbrescia, M.; Barbone, L.; Calabria, C.; Chhibra, S. S.; Colaleo, A.; Creanza, D.; De Filippis, N.; De Palma, M.; Fiore, L.; Iaselli, G.; Maggi, G.; Maggi, M.; Marangelli, B.; My, S.; Nuzzo, S.; Pacifico, N.; Pompili, A.; Pugliese, G.; Selvaggi, G.; Silvestris, L.; Singh, G.; Venditti, R.; Verwilligen, P.; Zito, G.; Abbiendi, G.; Benvenuti, A. C.; Bonacorsi, D.; Braibant-Giacomelli, S.; Brigliadori, L.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Cuffiani, M.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Grandi, C.; Guiducci, L.; Marcellini, S.; Masetti, G.; Meneghelli, M.; Montanari, A.; Navarria, F. L.; Odorici, F.; Perrotta, A.; Primavera, F.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Tosi, N.; Travaglini, R.; Albergo, S.; Cappello, G.; Chiorboli, M.; Costa, S.; Potenza, R.; Tricomi, A.; Tuve, C.; Barbagli, G.; Ciulli, V.; Civinini, C.; D’Alessandro, R.; Focardi, E.; Frosali, S.; Gallo, E.; Gonzi, S.; Meschini, M.; Paoletti, S.; Sguazzoni, G.; Tropiano, A.; Benussi, L.; Bianco, S.; Colafranceschi, S.; Fabbri, F.; Piccolo, D.; Fabbricatore, P.; Musenich, R.; Tosi, S.; Benaglia, A.; De Guio, F.; Di Matteo, L.; Fiorendi, S.; Gennai, S.; Ghezzi, A.; Lucchini, M. T.; Malvezzi, S.; Manzoni, R. A.; Martelli, A.; Massironi, A.; Menasce, D.; Moroni, L.; Paganoni, M.; Pedrini, D.; Ragazzi, S.; Redaelli, N.; Tabarelli de Fatis, T.; Buontempo, S.; Cavallo, N.; De Cosa, A.; Dogangun, O.; Fabozzi, F.; Iorio, A. O. M.; Lista, L.; Meola, S.; Merola, M.; Paolucci, P.; Azzi, P.; Bacchetta, N.; Bisello, D.; Branca, A.; Carlin, R.; Checchia, P.; Dorigo, T.; Galanti, M.; Gasparini, F.; Gasparini, U.; Gozzelino, A.; Kanishchev, K.; Lacaprara, S.; Lazzizzera, I.; Margoni, M.; Meneguzzo, A. T.; Pazzini, J.; Pegoraro, M.; Pozzobon, N.; Ronchese, P.; Simonetto, F.; Torassa, E.; Tosi, M.; Vanini, S.; Zotto, P.; Zumerle, G.; Gabusi, M.; Ratti, S. P.; Riccardi, C.; Torre, P.; Vitulo, P.; Biasini, M.; Bilei, G. M.; Fanò, L.; Lariccia, P.; Mantovani, G.; Menichelli, M.; Nappi, A.; Romeo, F.; Saha, A.; Santocchia, A.; Spiezia, A.; Taroni, S.; Azzurri, P.; Bagliesi, G.; Bernardini, J.; Boccali, T.; Broccolo, G.; Castaldi, R.; D’Agnolo, R. T.; Dell’Orso, R.; Fiori, F.; Foà, L.; Giassi, A.; Kraan, A.; Ligabue, F.; Lomtadze, T.; Martini, L.; Messineo, A.; Palla, F.; Rizzi, A.; Serban, A. T.; Spagnolo, P.; Squillacioti, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Barone, L.; Cavallari, F.; Del Re, D.; Diemoz, M.; Fanelli, C.; Grassi, M.; Longo, E.; Meridiani, P.; Micheli, F.; Nourbakhsh, S.; Organtini, G.; Paramatti, R.; Rahatlou, S.; Soffi, L.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Biino, C.; Cartiglia, N.; Casasso, S.; Costa, M.; Demaria, N.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Musich, M.; Obertino, M. M.; Pastrone, N.; Pelliccioni, M.; Potenza, A.; Romero, A.; Ruspa, M.; Sacchi, R.; Solano, A.; Staiano, A.; Belforte, S.; Candelise, V.; Casarsa, M.; Cossutti, F.; Della Ricca, G.; Gobbo, B.; Marone, M.; Montanino, D.; Penzo, A.; Schizzi, A.; Kim, T. Y.; Nam, S. K.; Chang, S.; Kim, D. H.; Kim, G. N.; Kong, D. J.; Park, H.; Son, D. C.; Kim, J. Y.; Kim, Zero J.; Song, S.; Choi, S.; Gyun, D.; Hong, B.; Jo, M.; Kim, H.; Kim, T. J.; Lee, K. S.; Moon, D. H.; Park, S. K.; Roh, Y.; Choi, M.; Kim, J. H.; Park, C.; Park, I. C.; Park, S.; Ryu, G.; Choi, Y.; Choi, Y. K.; Goh, J.; Kim, M. S.; Kwon, E.; Lee, B.; Lee, J.; Lee, S.; Seo, H.; Yu, I.; Bilinskas, M. J.; Grigelionis, I.; Janulis, M.; Juodagalvis, A.; Castilla-Valdez, H.; De La Cruz-Burelo, E.; Heredia-de La Cruz, I.; Lopez-Fernandez, R.; Martínez-Ortega, J.; Sanchez-Hernandez, A.; Villasenor-Cendejas, L. M.; Carrillo Moreno, S.; Vazquez Valencia, F.; Salazar Ibarguen, H. A.; Casimiro Linares, E.; Morelos Pineda, A.; Reyes-Santos, M. A.; Krofcheck, D.; Bell, A. J.; Butler, P. H.; Doesburg, R.; Reucroft, S.; Silverwood, H.; Ahmad, M.; Asghar, M. I.; Butt, J.; Hoorani, H. R.; Khalid, S.; Khan, W. A.; Khurshid, T.; Qazi, S.; Shah, M. A.; Shoaib, M.; Bialkowska, H.; Boimska, B.; Frueboes, T.; Górski, M.; Kazana, M.; Nawrocki, K.; Romanowska-Rybinska, K.; Szleper, M.; Wrochna, G.; Zalewski, P.; Brona, G.; Bunkowski, K.; Cwiok, M.; Dominik, W.; Doroba, K.; Kalinowski, A.; Konecki, M.; Krolikowski, J.; Misiura, M.; Wolszczak, W.; Almeida, N.; Bargassa, P.; David, A.; Faccioli, P.; Ferreira Parracho, P. G.; Gallinaro, M.; Seixas, J.; Varela, J.; Vischia, P.; Belotelov, I.; Bunin, P.; Gavrilenko, M.; Golutvin, I.; Gorbunov, I.; Kamenev, A.; Karjavin, V.; Kozlov, G.; Lanev, A.; Malakhov, A.; Moisenz, P.; Palichik, V.; Perelygin, V.; Shmatov, S.; Smirnov, V.; Volodko, A.; Zarubin, A.; Evstyukhin, S.; Golovtsov, V.; Ivanov, Y.; Kim, V.; Levchenko, P.; Murzin, V.; Oreshkin, V.; Smirnov, I.; Sulimov, V.; Uvarov, L.; Vavilov, S.; Vorobyev, A.; Vorobyev, An.; Andreev, Yu.; Dermenev, A.; Gninenko, S.; Golubev, N.; Kirsanov, M.; Krasnikov, N.; Matveev, V.; Pashenkov, A.; Tlisov, D.; Toropin, A.; Epshteyn, V.; Erofeeva, M.; Gavrilov, V.; Kossov, M.; Lychkovskaya, N.; Popov, V.; Safronov, G.; Semenov, S.; Shreyber, I.; Stolin, V.; Vlasov, E.; Zhokin, A.; Andreev, V.; Azarkin, M.; Dremin, I.; Kirakosyan, M.; Leonidov, A.; Mesyats, G.; Rusakov, S. V.; Vinogradov, A.; Belyaev, A.; Bogdanova, G.; Boos, E.; Khein, L.; Klyukhin, V.; Kodolova, O.; Lokhtin, I.; Lukina, O.; Markina, A.; Obraztsov, S.; Perfilov, M.; Petrushanko, S.; Popov, A.; Proskuryakov, A.; Sarycheva, L.; Savrin, V.; Volkov, V.; Azhgirey, I.; Bayshev, I.; Bitioukov, S.; Grishin, V.; Kachanov, V.; Konstantinov, D.; Krychkine, V.; Petrov, V.; Ryutin, R.; Sobol, A.; Tourtchanovitch, L.; Troshin, S.; Tyurin, N.; Uzunian, A.; Volkov, A.; Adzic, P.; Djordjevic, M.; Ekmedzic, M.; Krpic, D.; Milosevic, J.; Aguilar-Benitez, M.; Alcaraz Maestre, J.; Arce, P.; Battilana, C.; Calvo, E.; Cerrada, M.; Chamizo Llatas, M.; Colino, N.; De La Cruz, B.; Delgado Peris, A.; Domínguez Vázquez, D.; Fernandez Bedoya, C.; Fernández Ramos, J. P.; Ferrando, A.; Flix, J.; Fouz, M. C.; Garcia-Abia, P.; Gonzalez Lopez, O.; Goy Lopez, S.; Hernandez, J. M.; Josa, M. I.; Merino, G.; Puerta Pelayo, J.; Quintario Olmeda, A.; Redondo, I.; Romero, L.; Santaolalla, J.; Soares, M. S.; Willmott, C.; Albajar, C.; Codispoti, G.; de Trocóniz, J. F.; Brun, H.; Cuevas, J.; Fernandez Menendez, J.; Folgueras, S.; Gonzalez Caballero, I.; Lloret Iglesias, L.; Piedra Gomez, J.; Brochero Cifuentes, J. A.; Cabrillo, I. J.; Calderon, A.; Chuang, S. H.; Duarte Campderros, J.; Felcini, M.; Fernandez, M.; Gomez, G.; Gonzalez Sanchez, J.; Graziano, A.; Jorda, C.; Lopez Virto, A.; Marco, J.; Marco, R.; Martinez Rivero, C.; Matorras, F.; Munoz Sanchez, F. J.; Rodrigo, T.; Rodríguez-Marrero, A. Y.; Ruiz-Jimeno, A.; Scodellaro, L.; Vila, I.; Vilar Cortabitarte, R.; Abbaneo, D.; Auffray, E.; Auzinger, G.; Bachtis, M.; Baillon, P.; Ball, A. H.; Barney, D.; Bendavid, J.; Benitez, J. F.; Bernet, C.; Bianchi, G.; Bloch, P.; Bocci, A.; Bonato, A.; Botta, C.; Breuker, H.; Camporesi, T.; Cerminara, G.; Christiansen, T.; Coarasa Perez, J. 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I.; Vlimant, J. R.; Wöhri, H. K.; Worm, S. D.; Zeuner, W. D.; Bertl, W.; Deiters, K.; Erdmann, W.; Gabathuler, K.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; König, S.; Kotlinski, D.; Langenegger, U.; Meier, F.; Renker, D.; Rohe, T.; Bachmair, F.; Bäni, L.; Bortignon, P.; Buchmann, M. A.; Casal, B.; Chanon, N.; Deisher, A.; Dissertori, G.; Dittmar, M.; Donegà, M.; Dünser, M.; Eller, P.; Freudenreich, K.; Grab, C.; Hits, D.; Lecomte, P.; Lustermann, W.; Marini, A. C.; Martinez Ruiz del Arbol, P.; Mohr, N.; Moortgat, F.; Nägeli, C.; Nef, P.; Nessi-Tedaldi, F.; Pandolfi, F.; Pape, L.; Pauss, F.; Peruzzi, M.; Ronga, F. J.; Rossini, M.; Sala, L.; Sanchez, A. K.; Starodumov, A.; Stieger, B.; Takahashi, M.; Tauscher, L.; Thea, A.; Theofilatos, K.; Treille, D.; Urscheler, C.; Wallny, R.; Weber, H. A.; Wehrli, L.; Amsler, C.; Chiochia, V.; Favaro, C.; Ivova Rikova, M.; Kilminster, B.; Millan Mejias, B.; Otiougova, P.; Robmann, P.; Snoek, H.; Tupputi, S.; Verzetti, M.; Cardaci, M.; Chang, Y. H.; Chen, K. H.; Ferro, C.; Kuo, C. M.; Li, S. W.; Lin, W.; Lu, Y. J.; Singh, A. P.; Volpe, R.; Yu, S. S.; Bartalini, P.; Chang, P.; Chang, Y. H.; Chang, Y. W.; Chao, Y.; Chen, K. F.; Dietz, C.; Grundler, U.; Hou, W. -S.; Hsiung, Y.; Kao, K. Y.; Lei, Y. J.; Lu, R. -S.; Majumder, D.; Petrakou, E.; Shi, X.; Shiu, J. G.; Tzeng, Y. M.; Wan, X.; Wang, M.; Asavapibhop, B.; Simili, E.; Srimanobhas, N.; Suwonjandee, N.; Adiguzel, A.; Bakirci, M. N.; Cerci, S.; Dozen, C.; Dumanoglu, I.; Eskut, E.; Girgis, S.; Gokbulut, G.; Gurpinar, E.; Hos, I.; Kangal, E. E.; Karaman, T.; Karapinar, G.; Kayis Topaksu, A.; Onengut, G.; Ozdemir, K.; Ozturk, S.; Polatoz, A.; Sogut, K.; Sunar Cerci, D.; Tali, B.; Topakli, H.; Vergili, M.; Akin, I. V.; Aliev, T.; Bilin, B.; Bilmis, S.; Deniz, M.; Gamsizkan, H.; Guler, A. M.; Ocalan, K.; Ozpineci, A.; Serin, M.; Sever, R.; Surat, U. E.; Yalvac, M.; Zeyrek, M.; Gülmez, E.; Isildak, B.; Kaya, M.; Kaya, O.; Ozkorucuklu, S.; Sonmez, N.; Bahtiyar, H.; Barlas, E.; Cankocak, K.; Günaydin, Y. O.; Vardarlı, F. I.; Yücel, M.; Levchuk, L.; Brooke, J. J.; Clement, E.; Cussans, D.; Flacher, H.; Frazier, R.; Goldstein, J.; Grimes, M.; Heath, G. P.; Heath, H. F.; Kreczko, L.; Metson, S.; Newbold, D. M.; Nirunpong, K.; Poll, A.; Senkin, S.; Smith, V. J.; Williams, T.; Basso, L.; Bell, K. W.; Belyaev, A.; Brew, C.; Brown, R. M.; Cockerill, D. J. A.; Coughlan, J. A.; Harder, K.; Harper, S.; Jackson, J.; Kennedy, B. W.; Olaiya, E.; Petyt, D.; RadburnSmith, B. C.; Shepherd-Themistocleous, C. H.; Tomalin, I. R.; Womersley, W. J.; Bainbridge, R.; Ball, G.; Beuselinck, R.; Buchmuller, O.; Colling, D.; Cripps, N.; Cutajar, M.; Dauncey, P.; Davies, G.; Della Negra, M.; Ferguson, W.; Fulcher, J.; Futyan, D.; Gilbert, A.; Guneratne Bryer, A.; Hall, G.; Hatherell, Z.; Hays, J.; Iles, G.; Jarvis, M.; Karapostoli, G.; Kenzie, M.; Lyons, L.; Magnan, A. -M.; Marrouche, J.; Mathias, B.; Nandi, R.; Nash, J.; Nikitenko, A.; Pela, J.; Pesaresi, M.; Petridis, K.; Pioppi, M.; Raymond, D. M.; Rogerson, S.; Rose, A.; Seez, C.; Sharp, P.; Sparrow, A.; Stoye, M.; Tapper, A.; Vazquez Acosta, M.; Virdee, T.; Wakefield, S.; Wardle, N.; Whyntie, T.; Chadwick, M.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Leggat, D.; Leslie, D.; Martin, W.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Hatakeyama, K.; Liu, H.; Scarborough, T.; Charaf, O.; Cooper, S. I.; Henderson, C.; Rumerio, P.; Avetisyan, A.; Bose, T.; Fantasia, C.; Heister, A.; Lawson, P.; Lazic, D.; Rohlf, J.; Sperka, D.; St. John, J.; Sulak, L.; Alimena, J.; Bhattacharya, S.; Christopher, G.; Cutts, D.; Demiragli, Z.; Ferapontov, A.; Garabedian, A.; Heintz, U.; Jabeen, S.; Kukartsev, G.; Laird, E.; Landsberg, G.; Luk, M.; Narain, M.; Segala, M.; Sinthuprasith, T.; Speer, T.; Breedon, R.; Breto, G.; Calderon De La Barca Sanchez, M.; Caulfield, M.; Chauhan, S.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Dolen, J.; Erbacher, R.; Gardner, M.; Houtz, R.; Ko, W.; Kopecky, A.; Lander, R.; Mall, O.; Miceli, T.; Nelson, R.; Pellett, D.; Ricci-Tam, F.; Rutherford, B.; Searle, M.; Smith, J.; Squires, M.; Tripathi, M.; Vasquez Sierra, R.; Yohay, R.; Andreev, V.; Cline, D.; Cousins, R.; Duris, J.; Erhan, S.; Everaerts, P.; Farrell, C.; Hauser, J.; Ignatenko, M.; Jarvis, C.; Rakness, G.; Schlein, P.; Traczyk, P.; Valuev, V.; Weber, M.; Babb, J.; Clare, R.; Dinardo, M. E.; Ellison, J.; Gary, J. W.; Giordano, F.; Hanson, G.; Liu, H.; Long, O. R.; Luthra, A.; Nguyen, H.; Paramesvaran, S.; Sturdy, J.; Sumowidagdo, S.; Wilken, R.; Wimpenny, S.; Andrews, W.; Branson, J. G.; Cerati, G. B.; Cittolin, S.; Evans, D.; Holzner, A.; Kelley, R.; Lebourgeois, M.; Letts, J.; Macneill, I.; Mangano, B.; Padhi, S.; Palmer, C.; Petrucciani, G.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Sudano, E.; Tadel, M.; Tu, Y.; Vartak, A.; Wasserbaech, S.; Würthwein, F.; Yagil, A.; Yoo, J.; Barge, D.; Bellan, R.; Campagnari, C.; D’Alfonso, M.; Danielson, T.; Flowers, K.; Geffert, P.; George, C.; Golf, F.; Incandela, J.; Justus, C.; Kalavase, P.; Kovalskyi, D.; Krutelyov, V.; Lowette, S.; Magaña Villalba, R.; Mccoll, N.; Pavlunin, V.; Ribnik, J.; Richman, J.; Rossin, R.; Stuart, D.; To, W.; West, C.; Apresyan, A.; Bornheim, A.; Bunn, J.; Chen, Y.; Di Marco, E.; Duarte, J.; Gataullin, M.; Kcira, D.; Ma, Y.; Mott, A.; Newman, H. B.; Rogan, C.; Spiropulu, M.; Timciuc, V.; Veverka, J.; Wilkinson, R.; Xie, S.; Yang, Y.; Zhu, R. Y.; Azzolini, V.; Calamba, A.; Carroll, R.; Ferguson, T.; Iiyama, Y.; Jang, D. W.; Liu, Y. F.; Paulini, M.; Vogel, H.; Vorobiev, I.; Cumalat, J. P.; Drell, B. R.; Ford, W. T.; Gaz, A.; Luiggi Lopez, E.; Smith, J. G.; Stenson, K.; Ulmer, K. A.; Wagner, S. R.; Alexander, J.; Chatterjee, A.; Eggert, N.; Gibbons, L. K.; Heltsley, B.; Hopkins, W.; Khukhunaishvili, A.; Kreis, B.; Mirman, N.; Nicolas Kaufman, G.; Patterson, J. R.; Ryd, A.; Salvati, E.; Sun, W.; Teo, W. D.; Thom, J.; Thompson, J.; Tucker, J.; Weng, Y.; Winstrom, L.; Wittich, P.; Winn, D.; Abdullin, S.; Albrow, M.; Anderson, J.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Burkett, K.; Butler, J. N.; Chetluru, V.; Cheung, H. W. K.; Chlebana, F.; Cihangir, S.; Elvira, V. D.; Fisk, I.; Freeman, J.; Gao, Y.; Green, D.; Gutsche, O.; Hanlon, J.; Harris, R. M.; Hirschauer, J.; Hooberman, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Klima, B.; Kunori, S.; Kwan, S.; Leonidopoulos, C.; Linacre, J.; Lincoln, D.; Lipton, R.; Lykken, J.; Maeshima, K.; Marraffino, J. M.; Martinez Outschoorn, V. I.; Maruyama, S.; Mason, D.; McBride, P.; Mishra, K.; Mrenna, S.; Musienko, Y.; Newman-Holmes, C.; O’Dell, V.; Prokofyev, O.; Sexton-Kennedy, E.; Sharma, S.; Spalding, W. J.; Spiegel, L.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vidal, R.; Whitmore, J.; Wu, W.; Yang, F.; Yun, J. C.; Acosta, D.; Avery, P.; Bourilkov, D.; Chen, M.; Cheng, T.; Das, S.; De Gruttola, M.; Di Giovanni, G. P.; Dobur, D.; Drozdetskiy, A.; Field, R. D.; Fisher, M.; Fu, Y.; Furic, I. K.; Gartner, J.; Hugon, J.; Kim, B.; Konigsberg, J.; Korytov, A.; Kropivnitskaya, A.; Kypreos, T.; Low, J. F.; Matchev, K.; Milenovic, P.; Mitselmakher, G.; Muniz, L.; Remington, R.; Rinkevicius, A.; Skhirtladze, N.; Snowball, M.; Yelton, J.; Zakaria, M.; Gaultney, V.; Hewamanage, S.; Lebolo, L. M.; Linn, S.; Markowitz, P.; Martinez, G.; Rodriguez, J. L.; Adams, T.; Askew, A.; Bochenek, J.; Chen, J.; Diamond, B.; Gleyzer, S. V.; Haas, J.; Hagopian, S.; Hagopian, V.; Jenkins, M.; Johnson, K. F.; Prosper, H.; Veeraraghavan, V.; Weinberg, M.; Baarmand, M. M.; Dorney, B.; Hohlmann, M.; Kalakhety, H.; Vodopiyanov, I.; Yumiceva, F.; Adams, M. R.; Apanasevich, L.; Bai, Y.; Bazterra, V. E.; Betts, R. R.; Bucinskaite, I.; Callner, J.; Cavanaugh, R.; Evdokimov, O.; Gauthier, L.; Gerber, C. E.; Hofman, D. J.; Khalatyan, S.; Lacroix, F.; O’Brien, C.; Silkworth, C.; Strom, D.; Turner, P.; Varelas, N.; Akgun, U.; Albayrak, E. A.; Bilki, B.; Clarida, W.; Dilsiz, K.; Duru, F.; Griffiths, S.; Merlo, J. -P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Newsom, C. R.; Norbeck, E.; Ogul, H.; Onel, Y.; Ozok, F.; Sen, S.; Tan, P.; Tiras, E.; Wetzel, J.; Yetkin, T.; Yi, K.; Barnett, B. A.; Blumenfeld, B.; Bolognesi, S.; Fehling, D.; Giurgiu, G.; Gritsan, A. V.; Guo, Z. J.; Hu, G.; Maksimovic, P.; Swartz, M.; Whitbeck, A.; Baringer, P.; Bean, A.; Benelli, G.; Kenny, R. P.; Murray, M.; Noonan, D.; Sanders, S.; Stringer, R.; Tinti, G.; Wood, J. S.; Barfuss, A. F.; Bolton, T.; Chakaberia, I.; Ivanov, A.; Khalil, S.; Makouski, M.; Maravin, Y.; Shrestha, S.; Svintradze, I.; Gronberg, J.; Lange, D.; Rebassoo, F.; Wright, D.; Baden, A.; Calvert, B.; Eno, S. C.; Gomez, J. A.; Hadley, N. J.; Kellogg, R. G.; Kirn, M.; Kolberg, T.; Lu, Y.; Marionneau, M.; Mignerey, A. C.; Pedro, K.; Peterman, A.; Skuja, A.; Temple, J.; Tonjes, M. B.; Tonwar, S. C.; Apyan, A.; Bauer, G.; Busza, W.; Butz, E.; Cali, I. A.; Chan, M.; Dutta, V.; Gomez Ceballos, G.; Goncharov, M.; Kim, Y.; Klute, M.; Levin, A.; Luckey, P. D.; Ma, T.; Nahn, S.; Paus, C.; Ralph, D.; Roland, C.; Roland, G.; Stephans, G. S. F.; Stöckli, F.; Sumorok, K.; Sung, K.; Velicanu, D.; Wenger, E. A.; Wolf, R.; Wyslouch, B.; Yang, M.; Yilmaz, Y.; Yoon, A. S.; Zanetti, M.; Zhukova, V.; Dahmes, B.; De Benedetti, A.; Franzoni, G.; Gude, A.; Kao, S. C.; Klapoetke, K.; Kubota, Y.; Mans, J.; Pastika, N.; Rusack, R.; Sasseville, M.; Singovsky, A.; Tambe, N.; Turkewitz, J.; Cremaldi, L. M.; Kroeger, R.; Perera, L.; Rahmat, R.; Sanders, D. A.; Avdeeva, E.; Bloom, K.; Bose, S.; Claes, D. R.; Dominguez, A.; Eads, M.; Keller, J.; Kravchenko, I.; Lazo-Flores, J.; Malik, S.; Snow, G. R.; Godshalk, A.; Iashvili, I.; Jain, S.; Kharchilava, A.; Kumar, A.; Rappoccio, S.; Wan, Z.; Alverson, G.; Barberis, E.; Baumgartel, D.; Chasco, M.; Haley, J.; Nash, D.; Orimoto, T.; Trocino, D.; Wood, D.; Zhang, J.; Anastassov, A.; Hahn, K. A.; Kubik, A.; Lusito, L.; Mucia, N.; Odell, N.; Ofierzynski, R. A.; Pollack, B.; Pozdnyakov, A.; Schmitt, M.; Stoynev, S.; Velasco, M.; Won, S.; Berry, D.; Brinkerhoff, A.; Chan, K. M.; Hildreth, M.; Jessop, C.; Karmgard, D. J.; Kolb, J.; Lannon, K.; Luo, W.; Lynch, S.; Marinelli, N.; Morse, D. M.; Pearson, T.; Planer, M.; Ruchti, R.; Slaunwhite, J.; Valls, N.; Wayne, M.; Wolf, M.; Antonelli, L.; Bylsma, B.; Durkin, L. S.; Hill, C.; Hughes, R.; Kotov, K.; Ling, T. Y.; Puigh, D.; Rodenburg, M.; Smith, G.; Vuosalo, C.; Williams, G.; Winer, B. L.; Berry, E.; Elmer, P.; Halyo, V.; Hebda, P.; Hegeman, J.; Hunt, A.; Jindal, P.; Koay, S. A.; Lopes Pegna, D.; Lujan, P.; Marlow, D.; Medvedeva, T.; Mooney, M.; Olsen, J.; Piroué, P.; Quan, X.; Raval, A.; Saka, H.; Stickland, D.; Tully, C.; Werner, J. S.; Zenz, S. C.; Zuranski, A.; Brownson, E.; Lopez, A.; Mendez, H.; Ramirez Vargas, J. E.; Alagoz, E.; Barnes, V. E.; Benedetti, D.; Bolla, G.; Bortoletto, D.; De Mattia, M.; Everett, A.; Hu, Z.; Jones, M.; Koybasi, O.; Kress, M.; Laasanen, A. T.; Leonardo, N.; Maroussov, V.; Merkel, P.; Miller, D. H.; Neumeister, N.; Shipsey, I.; Silvers, D.; Svyatkovskiy, A.; Vidal Marono, M.; Yoo, H. D.; Zablocki, J.; Zheng, Y.; Guragain, S.; Parashar, N.; Adair, A.; Akgun, B.; Boulahouache, C.; Ecklund, K. M.; Geurts, F. J. M.; Li, W.; Padley, B. P.; Redjimi, R.; Roberts, J.; Zabel, J.; Betchart, B.; Bodek, A.; Chung, Y. S.; Covarelli, R.; de Barbaro, P.; Demina, R.; Eshaq, Y.; Ferbel, T.; Garcia-Bellido, A.; Goldenzweig, P.; Han, J.; Harel, A.; Miner, D. C.; Vishnevskiy, D.; Zielinski, M.; Bhatti, A.; Ciesielski, R.; Demortier, L.; Goulianos, K.; Lungu, G.; Malik, S.; Mesropian, C.; Arora, S.; Barker, A.; Chou, J. P.; Contreras-Campana, C.; Contreras-Campana, E.; Duggan, D.; Ferencek, D.; Gershtein, Y.; Gray, R.; Halkiadakis, E.; Hidas, D.; Lath, A.; Panwalkar, S.; Park, M.; Patel, R.; Rekovic, V.; Robles, J.; Rose, K.; Salur, S.; Schnetzer, S.; Seitz, C.; Somalwar, S.; Stone, R.; Thomas, S.; Walker, M.; Cerizza, G.; Hollingsworth, M.; Spanier, S.; Yang, Z. C.; York, A.; Eusebi, R.; Flanagan, W.; Gilmore, J.; Kamon, T.; Khotilovich, V.; Montalvo, R.; Osipenkov, I.; Pakhotin, Y.; Perloff, A.; Roe, J.; Safonov, A.; Sakuma, T.; Sengupta, S.; Suarez, I.; Tatarinov, A.; Toback, D.; Akchurin, N.; Damgov, J.; Dragoiu, C.; Dudero, P. R.; Jeong, C.; Kovitanggoon, K.; Lee, S. W.; Libeiro, T.; Volobouev, I.; Appelt, E.; Delannoy, A. G.; Florez, C.; Greene, S.; Gurrola, A.; Johns, W.; Kurt, P.; Maguire, C.; Melo, A.; Sharma, M.; Sheldon, P.; Snook, B.; Tuo, S.; Velkovska, J.; Arenton, M. W.; Balazs, M.; Boutle, S.; Cox, B.; Francis, B.; Goodell, J.; Hirosky, R.; Ledovskoy, A.; Lin, C.; Neu, C.; Wood, J.; Gollapinni, S.; Harr, R.; Karchin, P. E.; Kottachchi Kankanamge Don, C.; Lamichhane, P.; Sakharov, A.; Anderson, M.; Belknap, D. A.; Borrello, L.; Carlsmith, D.; Cepeda, M.; Dasu, S.; Friis, E.; Gray, L.; Grogg, K. S.; Grothe, M.; Hall-Wilton, R.; Herndon, M.; Hervé, A.; Klabbers, P.; Klukas, J.; Lanaro, A.; Lazaridis, C.; Loveless, R.; Mohapatra, A.; Mozer, M. U.; Ojalvo, I.; Palmonari, F.; Pierro, G. A.; Ross, I.; Savin, A.; Smith, W. H.; Swanson, J.

2013-04-01

The underlying event activity in proton-proton collisions at forward pseudo-rapidity (-6.6 < η < -5.2) is studied with the CMS detector at the LHC, using a novel observable: the ratio of the forward energy density, dE/dη, for events with a charged-particle jet produced at central pseudorapidity (|η^jet| < 2) to the forward energy density for inclusive events. This forward energy density ratio is measured as a function of the central jet transverse momentum, p (T), at three different pp centre-of-mass energies ( $\\sqrt{s}$ = 0.9, 2.76, and 7 TeV). In addition, the evolution of the forward energy density is studied in inclusive events and in events with a central jet. The results are compared to those of Monte Carlo event generators for pp collisions and are discussed in terms of the underlying event. Whereas the dependence of the forward energy density ratio on jet p_T at each separately can be well reproduced by some models, all models fail to simultaneously describe the increase of the forward energy density with in both inclusive events and in events with a central jet.

Intensification of family relations? Changes in the choice of marriage witnesses in the Netherlands, 1830-1950

NARCIS (Netherlands)

Bras, H.A.J.

2011-01-01

This study examines whether and why a process of intensification of family relations took place during the long nineteenth century by investigating Dutch marriage couples’ selection of witnesses. The results show that during the period 1830-1950, lateral kin (siblings, siblings-in-law and cousins)

Chambre de soin intensif et schizophrénie: quels impacts ?

OpenAIRE

Claude, Anaïs; Rerat, Océane; Rota, Edith; Lambelet, Catherine

2016-01-01

La mesure d’isolement est utilisée lors de comportement hétéro-agressif, auto-agressif ou encore lors d’un état d’agitation. Cependant, à ce jour, l’aspect thérapeutique de la chambre de soins intensifs n’est pas un acquis. Selon Bardet Blochet (2009) « l’utilisation de l’isolement est souvent perçu comme une mesure punitive, un moyen de contrôle social où s’intensifient des sentiments déjà présents d’exclusion, de rejet ou d’abandon » (p.559). Les soins infirmiers sont vus comme des échanges...

Post-process intensification of photographic silver images, using radioactive compounds

International Nuclear Information System (INIS)

1979-01-01

A method of post-process intensification of silver images on a developed and fixed photographic film or plate is described, comprising the steps of (a) converting silver of the developed film or plate to a radioactive compound by contracting the film or plate with an aqueous alkaline solution of an organo-S 35 compound which reacts selectively with silver in a photographic film or plate; (b) placing the film or plate treated in step (a) in direct contact with a receiver film which is sensitive to beta radiation whereby the receiver film is exposed by radiation from the radioactive compound; and (c) developing and fixing the resulting intensified receiver film. (author)

Ecological intensification to mitigate impacts of conventional intensive land use on pollinators and pollination

OpenAIRE

Kovács-Hostyánszki, Anikó; Espíndola, Anahí; Vanbergen, Adam J.; Settele, Josef; Kremen, Claire; Dicks, Lynn V.

2017-01-01

Worldwide, human appropriation of ecosystems is disrupting plant–pollinator communities and pollination function through habitat conversion and landscape homogenisation. Conversion to agriculture is destroying and degrading semi-natural ecosystems while conventional land-use intensification (e.g. industrial management of large-scale monocultures with high chemical inputs) homogenises landscape structure and quality. Together, these anthropogenic processes reduce the connectivity of population...

Sensitivity of Tropical-Cyclone Intensification to Perturbations in the Surface Drag Coefficient

Science.gov (United States)

2012-12-11

low-level region of intense hurricanes Allen (1980) and Hugo (1989). Mon. Weather Rev. 139: 1447–1462. c© 2012 Royal Meteorological Society Q. J. R. Meteorol. Soc. 140: 407–415 (2014) ...accurately forecast tropical-cyclone intensification and mature intensity. Key Words: hurricanes ; typhoons; wind–wave coupling Received 2 February 2012...10.1002/qj.2048 1. Introduction The boundary layer of a mature hurricane has been long recognized to be an important feature of the storm as it strongly

PEMBELAJARAN KETERAMPILAN MEMBACA INTENSIF PARAGRAF DENGAN MODEL PENGEMBANGAN KONSEP MELALUI AKTIVITAS BAHASA (PKMAB DAN MODEL PENDAHULUAN, PENGANALISISAN, PENGULANGAN (P3 PADA SISWA SMP DILIHAT DARI KARAKTERSOSIAL DAN MANDIRI

Directory of Open Access Journals (Sweden)

Nurriyah -

2014-08-01

Full Text Available Permasalahan penelitian adalah seberapa besar peningkatan keterampilan membaca intensif paragraf peserta didik yang berkarakter Sosialdan Mandiriyang diperlakukan dengan model pembelajaran PKMABdanP3di SMP. Tujuan penelitian ini untuk menentukan besaran hasil peningkatan keterampilan membaca intensif paragraf pada peserta didik yang berkarakter Sosialdan Mandiriyang diperlakukan dengan model pembelajaran PKMABdanP3di SMP.Penelitian menggunakan metode eksperimen dengan populasi keterampilan membaca intensif paragrafpeserta didik SMP di wilayah Tegal dan Brebes.Sampel penelitianadalah keterampilan membaca intensif paragrafpeserta didik Kelas VII SMP Warureja dan Brebes. Pengumpulan data kuantitatif dilaksanakan melalui tes keterampilan membaca intensif paragraf, dianalisismenggunakanbefore-after dant-Tes Dua Sampel Independen. Pengumpulan data kualitatif menggunakan panduan observasi, dokumentasi, dan angketskala sikap untuk mengungkap karakter peserta didik.Hasil penelitian membuktikan bahwa model PKMAB lebih efektif meningkatkan kemampuan membaca intensif paragraf pada peserta didik, terutama yang berkarakter Sosial. Sedangkan model P3 lebih efektif meningkatkan kemampuan membaca intensif paragraf pada peserta didik, terutama yang berkarakter Mandiri. The problem in this research is the comparison of intensive paragraph reading skill in the socializer children and in the children whose characters are director who are treated using PKMAB and P3 in Junior High School.The method used in this study was an experiment with quantitative and qualitative analysis techniques.The study sample is the intensive paragraph penganalisisaning skill on the students of grade VII of SMPN 1 Warureja and SMPN 5 Brebes. Quantitative data collection was carried out through intensive paragraph penganalisisaning test and analyzed by using before-after and t-Test for Two Independent Samples to know the level of intensive paragraph penganalisisaning skill on the learner

Maraviroc Intensification of cART in Patients with Suboptimal Immunological Recovery: A 48-Week, Placebo-Controlled Randomized Trial.

Directory of Open Access Journals (Sweden)

Steven F L van Lelyveld

Full Text Available The immunomodulatory effects of the CCR5-antagonist maraviroc might be beneficial in patients with a suboptimal immunological response, but results of different cART (combination antiretroviral therapy intensification studies are conflicting. Therefore, we performed a 48-week placebo-controlled trial to determine the effect of maraviroc intensification on CD4+ T-cell counts and immune activation in these patients.Double-blind, placebo-controlled, randomized trial.Major inclusion criteria were 1. CD4+ T-cell count <350 cells/μL while at least two years on cART or CD4+ T-cell count <200 cells/μL while at least one year on cART, and 2. viral suppression for at least the previous 6 months. HIV-infected patients were randomized to add maraviroc (41 patients or placebo (44 patients to their cART regimen for 48 weeks. Changes in CD4+ T-cell counts (primary endpoint and other immunological parameters were modeled using linear mixed effects models.No significant differences for the modelled increase in CD4+ T-cell count (placebo 15.3 CD4+ T cells/μL (95% confidence interval (CI [1.0, 29.5] versus maraviroc arm 22.9 CD4+ T cells/μL (95% CI [7.4, 38.5] p = 0.51 or alterations in the expression of markers for T-cell activation, proliferation and microbial translocation were found between the arms. However, maraviroc intensification did increase the percentage of CCR5 expressing CD4+ and CD8+ T-cells, and the plasma levels of the CCR5 ligand MIP-1β. In contrast, the percentage of ex-vivo apoptotic CD8+ and CD4+ T-cells decreased in the maraviroc arm.Maraviroc intensification of cART did not increase CD4+ T-cell restoration or decrease immune activation as compared to placebo. However, ex-vivo T-cell apoptosis was decreased in the maraviroc arm.ClinicalTrials.gov NCT00875368.

International trade, and land use intensification and spatial reorganization explain Costa Rica’s forest transition

Science.gov (United States)

Jadin, I.; Meyfroidt, P.; Lambin, E. F.

2016-03-01

While tropical deforestation remains widespread, some countries experienced a forest transition—a shift from net deforestation to net reforestation. Costa Rica had one of the highest deforestation rates in the 1980s and is now considered as a model of environmental sustainability, despite being a major producer of bananas and pineapples. We tested three land use processes that are thought to facilitate forest transitions. First, forest transitions may be accompanied by land use displacement through international trade of land-based products, which may undermine the global-scale environmental benefits of national forest protection. Second, reforestation is often associated with land use intensification in agriculture and forestry, allowing for land sparing. Third, this intensification may partly result from a geographical redistribution of land use at the sub-national scale to better match land use with land suitability. These hypotheses were verified for Costa Rica’s forest transition. We also tested whether forest increased mainly in regions with a low ecological value and agriculture expanded in regions with a high ecological value. Intensification and land use redistribution accounted for 76% of land spared during the forest transition, with 32% of this spared area corresponding to net reforestation. Decreasing meat exports led to a contraction of pastures, freeing an area equivalent to 80% of the reforested area. The forest transition in Costa Rica was environmentally beneficial at the global scale, with the reforested area over 1989-2013 corresponding to 130% of the land use displaced abroad through imports of agricultural products. However, expansion of export-oriented cropland caused deforestation in the most ecologically valuable regions of Costa Rica. Moreover, wood extraction from forest plantations increased to produce the pallets needed to export fruits. This highlights the importance of a multi-scale analysis when evaluating causes and impacts of

Projections of Heat Waves Events in the Intra-Americas Region Using Multimodel Ensemble

Directory of Open Access Journals (Sweden)

Moises Angeles-Malaspina

2018-01-01

Full Text Available Significant accelerated warming of the Sea Surface Temperature of 0.15°C per decade (1982–2012 was recently detected, which motivated the research for the present consequences and future projections on the heat index and heat waves in the intra-Americas region. Present records every six hours are retrieved from NCEP reanalysis (1948–2015 to calculate heat waves changes. Heat index intensification has been detected in the region since 1998 and driven by surface pressure changes, sinking air enhancement, and warm/weaker cold advection. This regional warmer atmosphere leads to heat waves intensification with changes in both frequency and maximum amplitude distribution. Future projections using a multimodel ensemble mean for five global circulation models were used to project heat waves in the future under two scenarios: RCP4.5 and RCP8.5. Massive heat waves events were projected at the end of the 21st century, particularly in the RCP8.5 scenario. Consequently, the regional climate change in the current time and in the future will require special attention to mitigate the more intense and frequent heat waves impacts on human health, countries’ economies, and energy demands in the IAR.

Indicators of agricultural intensity and intensification: a review of the literature

Directory of Open Access Journals (Sweden)

Irune Ruiz-Martinez

2015-06-01

Full Text Available Since the 1960s, research has dealt with agricultural intensification (AI as a solution to ensure global food security. Recently, sustainable intensification (SI has increasingly been used to describe those agricultural and farming systems that ensure adequate ecosystem service provision. Studies differ in terms of the application scales and methodologies, thus we aim to summarize the main findings from the literature on how AI and SI are assessed, from the farm to global levels. Our literature review is based on 7865 papers selected from the Web of Science database and analysed using CorText software. A further selection of 105 relevant papers was used for an in-depth full-text analysis on: i farming systems studied; ii related ecosystem services; iii indicators of intensity; and iv temporal and spatial scales of analysis. Through this two-step analysis we were able to highlight three main research gaps in the AI research indicators. Firstly, the farming systems analysed for assessing AI are often quite simplified or monoculture- oriented, and they do not take the diversity and complex organisation of farming systems into account. Secondly, these studies mainly focus on northern countries or developing countries, whereas there is a gap of knowledge in Mediterranean areas, which are the areas with a high complexity of farming systems and diversity in ecosystem services. Finally, AI is mostly assessed through nitrogen inputs and economic yield, which are used the most both at very local and global levels. Intermediate regional or local levels, which are relevant for policy implementation and local planning, are often neglected.

Magnetosphere energetics during substorm events IMP 8 and Geotail observations

CERN Document Server

Belehaki, A

2001-01-01

Magnetospheric energetics during substorm events is studied in this paper. Three events were selected, a weak substorm, a large isolated one and finally a prolonged period of substorm activity with multiple intensifications. It is assumed that the energy, that entered the magnetosphere due to electromagnetic coupling with the solar wind, is described by the epsilon parameter, proposed by Perreault and Akasofu (1978). High resolution, magnetic field and plasma data from the MGF and LEP experiments on board Geotail were analyzed to determine the timing of plasmoid release, its dimensions, its convection velocity and finally the energy carried by each plasmoid. Plasmoids were defined as structures with rotating magnetic fields and enhanced total pressure. Tailward plasmoid bulk speed in the distant tail varied from 350 to 750 km/s. Their dimensions in the X/sub GSM/ direction was found to be from 4.5 to 28 R/sub E/, and their duration did not exceed 5 min. The average energy carried by each plasmoid in the dista...

Elucidation of salvage laryngectomy pathologic and clinical variables to guide further treatment intensification investigation.

Science.gov (United States)

Scharpf, Joseph; Ward, Matthew; Adelstein, David; Koyfman, Shlomo; Li, Mingsi

2018-04-01

There are limited treatment options beyond surgical salvage for patients who fail nonoperative treatment for laryngeal squamous cell carcinoma. In this study, we examine the failure patterns after surgical salvage and the potential pathologic and clinical prognostic variables that might guide further postoperative intensification investigation. Retrospective analysis at a tertiary academic referral center. From an institutional review board-approved institutional head and neck cancer registry, a consecutive series of 147 patients who underwent salvage laryngectomy for squamous cell cancer recurrence or persistence after radiotherapy with or without chemotherapy between May 1995 and May 2016 were identified. Variables potentially associated with oncologic outcome after surgical salvage were then collected and retrospectively evaluated. The projected 2-year locoregional failure rate was 21.8% (95% confidence interval [CI], 14.6%-29.0%]), and the overall survival 65% (95% CI, 57.5%-74.3%) for the entire cohort after salvage laryngectomy. On multivariable analysis, sarcomatoid/spindle cell pathology (hazard ratio [HR], 3.147; 95% CI, 1.181-8.386; P = 0.022), lymphovascular space invasion (LVSI) (positive vs. negative; HR, 2.31; 95% CI, 1.21-4.42; P = 0.011), and advanced initial American Joint Committee on Cancer 7th Edition grouped stage (stages III-IVB vs. stages I-II; HR, 1.64; 95% CI, 1.04-2.6; P = 0.035) were found to be independently associated with inferior disease-free survival. No other clinical or pathologic variables predicted failure. Salvage laryngectomy after nonoperative treatment failure results in successful locoregional control rates and survival in the majority of patients failing initial therapy. This should temper enthusiasm for routine treatment intensification with postoperative re-irradiation and/or other systemic treatments for the vast majority of patients. Sarcomatoid pathology, LVSI, and an advanced initial stage are associated with inferior

Intensification of citrus production and soil loss in Eastern Spain

Science.gov (United States)

Cerdà, A.; González Peñaloza, F. A.; Burguet, M.; Giménez Morera, A.

2012-04-01

After land abandonment for five decades (Arnáez et al., 2010; Belmonte Serrato et al., 1999) as a widespread process in Spain, agriculture intensification is taken place. This is changing the nature of the soil erosion processes as they were known (Cerdà, 1997; Cammeraat and Imeson, 1999; Ruiz Sinoga et al., 2010; Zavala et al., 2010). Citrus production are being reallocated on slopes due to the new irrigation systems (drip-irrigation), the thermic inversion on the bottom of the valley and then the frost affecting the plantations, the high prices of the bottom valley lands and the investment in agriculture from other economic sectors such as tourism and industry. Those new plantations are based on intense pesticides and herbicides use, and erosion processes are triggered due to the sloping surface developed (Cerdà et al., 2010). Five study sites were selected in the Montesa Municipality research zone, where an increase in the orange and clementines plantations were found during the last 20 years. Measurements were perfomed by a simple method, which consist in measuring the surface characteristics: stoniness, crust, herbs, bare soil, sheet flow, rills and gullies. One thousand meters were monitored at each of the study sites and measurements were done in January and August with a precision of 1 cm. The results show that the erosion rates are controlled by the sheet erosion (78,4 %), although rill and gullies exist (managed new citrus plantation non sustainable. The intensification of agriculture is triggering new soil erosion processes to be added to the traditional ones (García Ruiz and López Bermúdez, 2009). This research study is being supported by the the research project CGL2008-02879/BTE

Sustainable intensification of U.S. agriculture: Aspirations and barriers in the regional agroecosystems of the LTAR network

Science.gov (United States)

The sustainable intensification of agriculture in the United States will require major shifts in producer decision-making, markets, and public policies. The Long-Term Agroecosystem Research (LTAR) network is working to better understand how these shifts may be accomplished. Through a common experime...

Rapid Learning of Adverse Medical Event Disclosure and Apology.

Science.gov (United States)

Raemer, Daniel B; Locke, Steven; Walzer, Toni Beth; Gardner, Roxane; Baer, Lee; Simon, Robert

2016-09-01

Despite published recommended best practices for full disclosure and apology to patients and families after adverse medical events, actual practice can be inadequate. The use of "cognitive aids" to help practitioners manage complex critical events has been successful in a variety of fields and healthcare. We wished to extend this concept to disclosure and apology events. The aim of this study was to test if a brief opportunity to review a best practice guideline for disclosure and apology would improve communication performance. Thirty pairs of experienced obstetricians and labor nurses participated in a 3-part exercise with mixed-realism simulation. The first part used a standardized actor patient to meet the obstetrical team. The second part used a high-fidelity simulation leading to an adverse medical event (retained sponge), and the third part used standardized actors, patient, and husband, who systematically move through stages of grief response. The participants were randomized into 2 groups, one was provided with a cognitive aid in the form of a best practice guideline for disclosure and apology and the other was only given time to plan. Four blinded raters working in pairs scored subjects on a 7-point scale using a previously developed assessment instrument modified for this study. Pooled ratings of the disclosure and apology discussion for the intervention group (n = 167, mean = 4.9, SD = 0.92) were higher than those from the control group (n = 167, mean = 4.3, SD = 1.21) (P apology conversation after reviewing a cognitive aid in the form of a best practice guideline than a control group that was only given time to prepare.

A System Designed for Rice? Materiality and the Invention/Discovery of the System of Rice Intensification

NARCIS (Netherlands)

Glover, D.

2011-01-01

The System of Rice Intensification (SRI) is a novel approach to rice cultivation that is claimed to be both more productive and more sustainable than conventional methods. It is said to have been discovered by a French Jesuit missionary working in Madagascar during the 1970s and 1980s. The system

Investigation of the differences between deepening and intensification for 500-hpa cyclones in central and East Mediterranean region during warm season of the year

Directory of Open Access Journals (Sweden)

S. Spanos

2006-01-01

Full Text Available The maximum deepening rate per cyclone track is determined by the maximum height drop at the center of the cyclone (500-hPa low on the basis of all the 6-h successive steps in its life cycle. The geopotential height gradient is calculated over the entire low area and the calculation continued with the variation of the gradient in the successive steps. The maximum intensification rate per cyclone is then determined as the maximum increase of the gradient in the life cycle. Maximum deepening rate for the 500-hPa cyclones in the area does not exceed, on average, 12 gpm/6 h. Maximum intensification which is 1.4 gpm/100 Km*6 h on average, occurs in the early stages of the cyclone's life cycle. This on the average happens approximately 9 h after the first time the low is detected. At the gulf of Genoa and the Adriatic Sea, cyclones usually show the maximum intensification after the maximum deepening. At Turkey's cyclogenesis area, however, this order is reversed. The spatial distributions of maximum intensification in the three sub-periods, indicate that it mainly occurs over Seas during late warm periods and over land during early and middle warm periods. Such a behavior underlines the role of low-level instability in cyclone development.

The Association of IFI27 Expression and Fatigue Intensification during Localized Radiation Therapy: Implication of a Para-Inflammatory Bystander Response

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Leorey N. Saligan

2013-08-01

Full Text Available The mechanisms behind fatigue intensification during cancer therapy remain elusive. The interferon alpha-inducible protein 27 (IFI27 was the most up-regulated gene based on our previous microarray data in fatigued men with non-metastatic prostate cancer receiving localized external beam radiation therapy (EBRT. The purpose of this study was to confirm the IFI27 up-regulation and determine its association with fatigue intensification during EBRT. Peripheral blood samples and fatigue scores were collected at three time points—prior to EBRT, at midpoint, and at completion of EBRT. Confirmatory quantitative real time polymerase chain reaction (qPCR and enzyme-linked immunosorbent assay (ELISA were utilized to verify the microarray results. Subjects were a total of 40 Caucasian men with prostate cancer; 20 scheduled for EBRT (65.6 ± 7.5 years old, and 20 on active surveillance as controls (62.8 ± 6.1 years old. Significant IFI27 expression overtime during EBRT was confirmed by qPCR (p < 0.5, which correlated with fatigue scores during EBRT (R = −0.90, p = 0.006. Alterations in mechanisms associated with immune response and mitochondrial function that explain the up-regulation of IFI27 may provide an understanding of the pathways related to the intensification of fatigue during localized radiation therapy.

Aquaculture: a rapidly growing and significant source of sustainable food? Status, transitions and potential.

Science.gov (United States)

Little, D C; Newton, R W; Beveridge, M C M

2016-08-01

The status and potential of aquaculture is considered as part of a broader food landscape of wild aquatic and terrestrial food sources. The rationale and resource base required for the development of aquaculture are considered in the context of broader societal development, cultural preferences and human needs. Attention is drawn to the uneven development and current importance of aquaculture globally as well as its considerable heterogeneity of form and function compared with established terrestrial livestock production. The recent drivers of growth in demand and production are examined and the persistent linkages between exploitation of wild stocks, full life cycle culture and the various intermediate forms explored. An emergent trend for sourcing aquaculture feeds from alternatives to marine ingredients is described and the implications for the sector with rapidly growing feed needs discussed. The rise of non-conventional and innovative feed ingredients, often shared with terrestrial livestock, are considered, including aquaculture itself becoming a major source of marine ingredients. The implications for the continued expected growth of aquaculture are set in the context of sustainable intensification, with the challenges that conventional intensification and emergent integration within, and between, value chains explored. The review concludes with a consideration of the implications for dependent livelihoods and projections for various futures based on limited resources but growing demand.

A 27,000 year record of Red Sea outflow: Implication for timing of post-glacial monsoon intensification

Digital Repository Service at National Institute of Oceanography (India)

Naqvi, S.W.A.; Fairbanks, R.G.

the cessation of deep water formation from 15,500 to 7,300 yr BP. It appears that the monsoon intensification did lag behind insolation until 15,500 yr BP. Between 15,500 and the present, however, there was no lag in conflict with the previous reports, implying...

An important role of the moisture supply from the Kuroshio Current/Kuroshio Extension in the rapid development of an explosive cyclone

Science.gov (United States)

Hirata, H.; Kawamura, R.; Kato, M.; Shinoda, T.

2014-12-01

We investigated how the moisture supply from the Kuroshio Current/Kuroshio Extension affects the rapid intensification of an explosive cyclone using a couple atmosphere-ocean non-hydrostatic model, CReSS-NHOES. The Cloud-Resolving Storm Simulator (CReSS) and the Non-Hydrostatic Ocean model for the Earth Simulator (NHOES) have been developed by the Hydrospheric Atmospheric Research Center of Nagoya University and the Japan Agency for Marine-Earth Science and Technology, respectively. We performed a numerical simulation of an extratropical cyclone migrating along the southern periphery of the Kuroshio Current on January 14, 2013, that developed most rapidly in recent years in the vicinity of Japan. The evolutions of surface fronts related to the cyclone simulated by the CReSS-NHOES closely resemble Shapiro-Keyser model. In the lower troposphere, the cyclone's bent-back front and the associated frontal T-bone structure become evident with the cyclone development. Cold Conveyor Belt (CCB) is also well organized over the northern part of the cyclone. During its developing stage, since the CCB dominates just over the Kuroshio Current/Kuroshio Extension, a large amount of moisture is efficiently supplied from the warm current into the CCB. The vapor evaporated from the underlying warm current is transported into the bent-back front by the CCB and converges horizontally in the vicinity of the front. As a result, strong diabatic heating arises over the corresponding moisture convergence area in that vicinity, indicating that the abundant moisture due to the warm current plays a vital role in rapid development of the cyclone through latent heat release processes. Both processes of the moisture transport from the warm current into the cyclone system via the CCB and of the latent heat release around the bent-back front are also confirmed by trajectory analyses. The rapid SLP decrease of the cyclone center can in turn increase the moisture supply from the warm current through

Prodigious Effects of Concentration Intensification on Nanoparticle Synthesis: A High-Quality, Scalable Approach

KAUST Repository

Williamson, Curtis B.

2015-12-23

© 2015 American Chemical Society. Realizing the promise of nanoparticle-based technologies demands more efficient, robust synthesis methods (i.e., process intensification) that consistently produce large quantities of high-quality nanoparticles (NPs). We explored NP synthesis via the heat-up method in a regime of previously unexplored high concentrations near the solubility limit of the precursors. We discovered that in this highly concentrated and viscous regime the NP synthesis parameters are less sensitive to experimental variability and thereby provide a robust, scalable, and size-focusing NP synthesis. Specifically, we synthesize high-quality metal sulfide NPs (<7% relative standard deviation for Cu2-xS and CdS), and demonstrate a 10-1000-fold increase in Cu2-xS NP production (>200 g) relative to the current field of large-scale (0.1-5 g yields) and laboratory-scale (<0.1 g) efforts. Compared to conventional synthesis methods (hot injection with dilute precursor concentration) characterized by rapid growth and low yield, our highly concentrated NP system supplies remarkably controlled growth rates and a 10-fold increase in NP volumetric production capacity (86 g/L). The controlled growth, high yield, and robust nature of highly concentrated solutions can facilitate large-scale nanomanufacturing of NPs by relaxing the synthesis requirements to achieve monodisperse products. Mechanistically, our investigation of the thermal and rheological properties and growth rates reveals that this high concentration regime has reduced mass diffusion (a 5-fold increase in solution viscosity), is stable to thermal perturbations (64% increase in heat capacity), and is resistant to Ostwald ripening.

Wavelet spectra of JACEE events

International Nuclear Information System (INIS)

Suzuki, Naomichi; Biyajima, Minoru; Ohsawa, Akinori.

1995-01-01

Pseudo-rapidity distributions of two high multiplicity events Ca-C and Si-AgBr observed by the JACEE are analyzed by a wavelet transform. Wavelet spectra of those events are calculated and compared with the simulation calculations. The wavelet spectrum of the Ca-C event somewhat resembles that simulated with the uniform random numbers. That of Si-AgBr event, however, is not reproduced by simulation calculations with Poisson random numbers, uniform random numbers, or a p-model. (author)

Naturalistic rapid deceleration data: Drivers aged 75 years and older

Directory of Open Access Journals (Sweden)

Anna Chevalier

2016-12-01

Full Text Available The data presented in this article are related to the research manuscript “Predictors of older drivers’ involvement in rapid deceleration events”, which investigates potential predictors of older drivers’ involvement in rapid deceleration events including measures of vision, cognitive function and driving confidence (A. Chevalier et al., 2016 [1]. In naturalistic driving studies such as this, when sample size is not large enough to allow crashes to be used to investigate driver safety, rapid deceleration events may be used as a surrogate safety measure. Naturalistic driving data were collected for up to 52 weeks from 182 volunteer drivers aged 75–94 years (median 80 years, 52% male living in the suburban outskirts of Sydney. Driving data were collected using an in-vehicle monitoring device. Accelerometer data were recorded 32 times per second and Global Positioning System (GPS data each second. To measure rapid deceleration behavior, rapid deceleration events (RDEs were defined as having at least one data point at or above the deceleration threshold of 750 milli-g (7.35 m/s2. All events were constrained to a maximum 5 s duration. The dataset provided with this article contains 473 events, with a row per RDE. This article also contains information about data processing, treatment and quality control. The methods and data presented here may assist with planning and analysis of future studies into rapid deceleration behaviour using in-vehicle monitoring.

Role of Urbanization, Land-Use Diversity, and Livestock Intensification in Zoonotic Emerging Infectious Diseases

OpenAIRE

Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh; Castrence, Miguel; Nong, Duong; Spencer, James; Lam, Nguyen; Finucane, Melissa; Duc Vien, Tran; Wilcox, Bruce

2014-01-01

Emerging infectious diseases (EIDs) continue to significantly threaten human and animal health. While there has been some progress in identifying underlying proximal driving forces and causal mechanisms of disease emergence, the role of distal factors is most poorly understood. This article focuses on analyzing the statistical association between highly pathogenic avian influenza (HPAI) H5N1 and urbanization, land-use diversity and poultry intensification. A special form of the urban transiti...

Land use intensification alters ecosystem multifunctionality via loss of biodiversity and changes to functional composition.

OpenAIRE

Allan Eric; Manning Pete; Alt Fabian; Binkenstein Julia; Blaser Stefan; Blüthgen Nico; Böhm Stefan; Grassein Fabrice; Hölzel Norbert; Klaus Valentin H.; Kleinebecker Till; Morrys Elisabeth Kathryn; Oelmann Yvonne; Prati Daniel; Renner Sven C.

2015-01-01

Abstract Global change, especially land?use intensification, affects human well?being by impacting the delivery of multiple ecosystem services (multifunctionality). However, whether biodiversity loss is a major component of global change effects on multifunctionality in real?world ecosystems, as in experimental ones, remains unclear. Therefore, we assessed biodiversity, functional composition and 14 ecosystem services on 150 agricultural grasslands differing in land?use intensity. We also int...

Intensification of Chile-Peru upwelling under climate change: diagnosing the impact of natural and anthropogenic forcing from the IPSL-CM5 model.

Science.gov (United States)

Jebri, B.; Khodri, M.; Gastineau, G.; Echevin, V.; Thiria, S.

2017-12-01

Upwelling is critical to the biological production, acidification, and deoxygenation of the ocean's major eastern boundary current ecosystems. A conceptual hypothesis suggests that the winds that favour coastal upwelling intensify with anthropogenic global warming due to increased land-sea temperature contrast. We examine this hypothesis for the dynamics of the Peru-Chile upwelling using a set of four large ensembles of coupled, ocean-atmosphere model simulations with the IPSL model covering the 1940-2014 period. In one large ensemble we prescribe the standard CMIP5 greenhouse gas (GHG) concentrations, anthropogenic aerosol, ozone and volcanic forcings, following the historical experiments through 2005 and RCP8.5 from 2006-2014, while the other ensembles consider separately the GHG, ozone and volcanic forcings. We find evidence for intensification of upwelling-favourable winds with however little evidence of atmospheric pressure gradients in response to increasing land-sea temperature differences. Our analyses reveal poleward migration and intensification of the South Pacific Anticyclone near poleward boundaries of climatological Peruvian and Chilean upwelling zones. This contribution further investigates the physical mechanisms for the Peru-Chile upwelling intensification and the relative role of natural and anthropogenic forcings.

Matrix Intensification Affects Body and Physiological Condition of Tropical Forest-Dependent Passerines.

Science.gov (United States)

Deikumah, Justus P; McAlpine, Clive A; Maron, Martine

2015-01-01

Matrix land-use intensification is a relatively recent and novel landscape change that can have important influences on the biota within adjacent habitat patches. While there are immediate local changes that it brings about, the influences on individual animals occupying adjacent habitats may be less evident initially. High-intensity land use could induce chronic stress in individuals in nearby remnants, leading ultimately to population declines. We investigated how physiological indicators and body condition measures of tropical forest-dependent birds differ between forest adjacent to surface mining sites and that near farmlands at two distances from remnant edge in southwest Ghana. We used mixed effects models of several condition indices including residual body mass and heterophil to lymphocyte (H/L) ratios (an indicator of elevated chronic stress) to explore the effect of matrix intensity on forest-dependent passerines classed as either sedentary area-sensitive habitat specialists or nomadic generalists. Individual birds occupying tropical forest remnants near surface mining sites were in poorer condition, as indicated by lower residual body mass and elevated chronic stress, compared to those in remnants near agricultural lands. The condition of the sedentary forest habitat specialists white-tailed alethe, Alethe diademata and western olive sunbird, Cyanomitra obscura was most negatively affected by high-intensity surface mining land-use adjacent to remnants, whereas generalist species were not affected. Land use intensification may set in train a new trajectory of faunal relaxation beyond that expected based on habitat loss alone. Patterns of individual condition may be useful in identifying habitats where species population declines may occur before faunal relaxation has concluded.

How Does Gender Affect Sustainable Intensification of Cereal Production in the West African Sahel? Evidence from Burkina Faso.

Science.gov (United States)

Theriault, Veronique; Smale, Melinda; Haider, Hamza

2017-04-01

Better understanding of gender differences in the adoption of agricultural intensification strategies is crucial for designing effective policies to close the gender gap while sustainably enhancing farm productivity. We examine gender differences in adoption rates, likelihood and determinants of adopting strategy sets that enhance yields, protect crops, and restore soils in the West African Sahel, based on analysis of cereal production in Burkina Faso. Applying a multivariate probit model to a nationally representative household panel, we exploit the individual plot as unit of analysis and control for plot manager characteristics along with other covariates. Reflecting the socio-cultural context of farming combined with the economic attributes of inputs, we find that female managers of individual cereal fields are less likely than their male counterparts to adopt yield-enhancing and soil-restoring strategies, although no differential is apparent for yield-protecting strategies. More broadly, gender-disaggregated regressions demonstrate that adoption determinants differ by gender. Plot manager characteristics, including age, marital status, and access to credit or extension services do influence adoption decisions. Furthermore, household resources influence the probability of adopting intensification strategy sets differently by gender of the plot manager. Variables expressing the availability of household labor strongly influence the adoption of soil-restoring strategies by female plot managers. By contrast, household resources such as extent of livestock owned, value of non-farm income, and area planted to cotton affect the adoption choices of male plot managers. Rectifying the male bias in extension services along with improving access to credit, income, and equipment to female plot managers could contribute to sustainable agricultural intensification.

Crop intensification, land use, and on-farm energy-use efficiency during the worldwide spread of the green revolution.

Science.gov (United States)

Pellegrini, Pedro; Fernández, Roberto J

2018-03-06

We analyzed crop production, physical inputs, and land use at the country level to assess technological changes behind the threefold increase in global crop production from 1961 to 2014. We translated machinery, fuel, and fertilizer to embedded energy units that, when summed up, provided a measure of agricultural intensification (human subsidy per hectare) for crops in the 58 countries responsible for 95% of global production. Worldwide, there was a 137% increase in input use per hectare, reaching 13 EJ, or 2.6% of the world's primary energy supply, versus only a 10% increase in land use. Intensification was marked in Asia and Latin America, where input-use levels reached those that North America and Europe had in the earlier years of the period; the increase was more accentuated, irrespective of continent, for the 12 countries with mostly irrigated production. Half of the countries (28/58), mainly developed ones, had an average subsidy >5 GJ/ha/y (with fertilizers accounting for 27% in 1961 and 45% in 2014), with most of them (23/28) using about the same area or less than in 1961 (net land sparing of 31 Mha). Most of the remaining countries (24/30 with inputs <5 GJ/ha/y), mainly developing ones, increased their cropped area (net land extensification of 135 Mha). Overall, energy-use efficiency (crop output/inputs) followed a U-shaped trajectory starting at about 3 and finishing close to 4. The prospects of a more sustainable intensification are discussed, and the inadequacy of the land-sparing model expectation of protecting wilderness via intensified agriculture is highlighted.

Soil conditions and land use intensification effects on soil microbial communities across a range of European field sites

NARCIS (Netherlands)

Thomson, Bruce C.; Tisserant, Emilie; Plassart, Pierre; Uroz, Stéphane; Griffiths, Rob I.; Hannula, S. Emilia; Buée, Marc; Mougel, Christophe; Ranjard, Lionel; Van Veen, Johannes A.; Martin, Francis; Bailey, Mark J.; Lemanceau, Philippe

2015-01-01

Abstract Intensive land use practices necessary for providing food and raw materials are known to have a deleterious effect on soil. However, the effects such practices have on soil microbes are less well understood. To investigate the effects of land use intensification on soil microbial

Possibilities for Near-term Bioenergy Production and GHG-Mitigation through Sustainable Intensification of Agriculture and Forestry in Denmark

DEFF Research Database (Denmark)

Larsen, Søren; Bentsen, Niclas S; Dalgaard, Tommy

2017-01-01

To mitigate climate change it is necessary to further increase the deployment of renewable energy, including bioenergy. This analysis shows how this can be achieved in Danish agriculture and forestry before 2020. The key is a sustainable intensification and we show through three scenarios how...

Agricultural Innovation Systems (AIS): A Study of Stakeholders and Their Relations in System of Rice Intensification (SRI)

Science.gov (United States)

Suchiradipta, Bhattacharjee; Raj, Saravanan

2015-01-01

Purpose: This paper identifies the stakeholders of System of Rice Intensification (SRI), their roles and actions and the supporting and enabling environment of innovation in the state as the elements of the Agricultural Innovation Systems (AIS) in SRI in Tripura state of India and studies the relationship matrix among the stakeholders.…

Zenith: A Radiosonde Detector for Rapid-Response Ionizing Atmospheric Radiation Measurements During Solar Particle Events

Science.gov (United States)

Dyer, A. C. R.; Ryden, K. A.; Hands, A. D. P.; Dyer, C.; Burnett, C.; Gibbs, M.

2018-03-01

Solar energetic particle events create radiation risks for aircraft, notably single-event effects in microelectronics along with increased dose to crew and passengers. In response to this, some airlines modify their flight routes after automatic alerts are issued. At present these alerts are based on proton flux measurements from instruments onboard satellites, so it is important that contemporary atmospheric radiation measurements are made and compared. This paper presents the development of a rapid-response system built around the use of radiosondes equipped with a radiation detector, Zenith, which can be launched from a Met Office weather station after significant solar proton level alerts are issued. Zenith is a compact, battery-powered solid-state radiation monitor designed to be connected to a Vaisala RS-92 radiosonde, which transmits all data to a ground station as it ascends to an altitude of 33 km. Zenith can also be operated as a stand-alone detector when connected to a laptop, providing real-time count rates. It can also be adapted for use on unmanned aerial vehicles. Zenith has been flown on the Met Office Civil Contingency Aircraft, taken to the European Organization for Nuclear Research-EU high energy Reference Field facility for calibration and launched on a meteorological balloon at the Met Office's weather station in Camborne, Cornwall, UK. During this sounding, Zenith measured the Pfotzer-Regener maximum to be at an altitude of 18-20 km where the count rate was measured to be 1.15 c s-1 cm-2 compared to 0.02 c s-1 cm-2 at ground level.

A model-data based systems approach to process intensification

DEFF Research Database (Denmark)

Gani, Rafiqul

. Their developments, however, are largely due to experiment based trial and error approaches and while they do not require validation, they can be time consuming and resource intensive. Also, one may ask, can a truly new intensified unit operation be obtained in this way? An alternative two-stage approach is to apply...... a model-based synthesis method to systematically generate and evaluate alternatives in the first stage and an experiment-model based validation in the second stage. In this way, the search for alternatives is done very quickly, reliably and systematically over a wide range, while resources are preserved...... for focused validation of only the promising candidates in the second-stage. This approach, however, would be limited to intensification based on “known” unit operations, unless the PI process synthesis/design is considered at a lower level of aggregation, namely the phenomena level. That is, the model-based...

The evolution of agricultural intensification and environmental degradation in the UK: a data-driven systems dynamics approach

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Armstrong McKay, David I.; Dearing, John A.; Dyke, James G.; Poppy, Guy; Firbank, Les

2016-04-01

The world's population continues to grow rapidly, yet the current demand for food is already resulting in environmental degradation in many regions. As a result, an emerging challenge of the 21st century is how agriculture can simultaneously undergo sustainable intensification and be made more resilient to accelerating climate change. Key to this challenge is: a) finding the "safe and just operating space" for the global agri-environment system that both provides sufficient food for humanity and avoids crossing dangerous planetary boundaries, and b) downscaling this framework from a planetary to a regional scale in order to better inform decision making and incorporate regional dynamics within the planetary boundaries framework. Regional safe operating spaces can be defined and explored using a combination of metrics that indicate the changing status of ecosystem services (both provisioning and regulating), statistical techniques that reveal early warning signals and breakpoints, and dynamical system models of the regional agri-environment system. Initial attempts to apply this methodology have been made in developing countries (e.g. China [Dearing et al., 2012, 2014; Zhang et al., 2015]), but have not yet been attempted in more developed countries, for example the UK. In this study we assess the changes in ecosystem services in two contrasting agricultural regions in the UK, arable-dominated East England and pastoral-dominated South-West England, since the middle of the 20th Century. We identify and establish proxies and indices of various provisioning and regulating services in these two regions and analyse how these have changed over this time. We find that significant degradation of regulating services occurred in Eastern England in the early 1980s, reflecting a period of rapid intensification and escalating fertiliser usage, but that regulating services have begun to recover since 2000 mainly as a result of fertiliser usage decoupling from increasing wheat

Bequest of the Norseman—The Potential for Agricultural Intensification and Expansion in Southern Greenland under Climate Change

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Chatrina Caviezel

2017-12-01

Full Text Available The increase of summer temperatures and a prolonged growing season increase the potential for agricultural land use for subarctic agriculture. Nevertheless, land use at borderline ecotones is influenced by more factors than temperature and the length of the growing season, for example soil quality, as the increasing lengths of dry periods during vegetation season can diminish land use potential. Hence, this study focuses on the quality of the soil resource as possible limiting factor for land use intensification in southern Greenland. Physical and chemical soil properties of cultivated grasslands, reference sites and semi-natural birch and grassland sites were examined to develop a soil quality index and to identify the suitability of soils for a sustainable intensification and expansion of the agriculture. The study revealed that soils in the study area are generally characterized by a low effective cation exchange capacity (CECeff (3.7 ± 5.0 meq 100 g−1, low pH CaCl2 (4.6 ± 0.4 and low clay and silt content (3.0 ± 1.0% and 38.2 ± 4.7%, respectively. Due to the high amount of coarse fraction (59.1 ± 5.8% and the low amount of soil nutrients, an increasing threat of dry spells for soils and yield could be identified. Further, future land use intensification and expansion bears a high risk for concomitant effects, namely further soil acidification, nutrient leaching and soil degradation processes. However, results of the soil quality index also indicate that sites which were already used by the Norseman (980s–1450 show the best suitability for agricultural use. Thus, these areas offer a possibility to expand agricultural land use in southern Greenland.

What's behind the Name? The Intensification of Co-Branding in Elite US Colleges of Business and Education

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Mars, Matthew M.

2010-01-01

This article presents research that draws attention to the intensification of co-branding within elite US graduate colleges of business and education. A robust set of descriptive data collected and analyzed according to a content analysis strategy is used to develop an initial understanding of the trend of naming of colleges and academic units in…

Rapid climate variability during warm and cold periods in polar regions and Europe

DEFF Research Database (Denmark)

Masson-Delmotte, V.; Landais, A.; Combourieu-Nebout, N.

2005-01-01

Typical rapid climate events punctuating the last glacial period in Greenland, Europe and Antarctica are compared to two rapid events occurring under warmer conditions: (i) Dansgaard-Oeschger event 25, the first abrupt warming occurring during last glacial inception; (ii) 8.2 ka BP event, the only...... rapid cooling recorded during the Holocene in Greenland ice cores and in Ammersee, Germany. The rate of warming during previous warmer interglacial periods is estimated from polar ice cores to 1.5 °C per millennium, without abrupt changes. Climate change expected for the 21st century should however...

Event Boundaries in Memory and Cognition.

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Radvansky, Gabriel A; Zacks, Jeffrey M

2017-10-01

Research on event cognition is rapidly developing and is revealing fundamental aspects of human cognition. In this paper, we review recent and current work that is driving this field forward. We first outline the Event Horizon Model, which broadly describes the impact of event boundaries on cognition and memory. Then, we address recent work on event segmentation, the role of event cognition in working memory and long-term memory, including event model updating, and long term retention. Throughout we also consider how event cognition varies across individuals and groups of people and consider the neural mechanisms involved.

A 27,000 year record of Red Sea Outflow: Implication for timing of post-glacial monsoon intensification

Science.gov (United States)

Naqvi, Wajih A.; Fairbanks, Richard G.

We reconstruct here the history of the Red Sea Outflow (RSO) over the past 27,000 years from an AMS 14C-dated high-resolution δ13C record of benthic foraminifera from the inner Gulf of Aden assuming the dominance of circulation over productivity in regulating benthic δ13C. The results reveal that, following a period of suppressed RSO due to shallow sill 24,000-18,000 yr BP, the Red Sea was vigorously flushed for ˜2,000 years before a major monsoon intensification caused the cessation of deep water formation from 15,500 to 7,300 yr BP. It appears that the monsoon intensification did lag behind insolation until 15,500 yr BP. Between 15,500 and the present, however, there was no lag in conflict with the previous reports, implying a negligible dampening effect of continental albedo during this period. However, since our analysis is confined to a single depth horizon and our record is sensitive to sea level, it has some limitations as an indicator of monsoon intensity.

Rapid Genome-wide Recruitment of RNA Polymerase II Drives Transcription, Splicing, and Translation Events during T Cell Responses

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Kathrin Davari

2017-04-01

Full Text Available Summary: Activation of immune cells results in rapid functional changes, but how such fast changes are accomplished remains enigmatic. By combining time courses of 4sU-seq, RNA-seq, ribosome profiling (RP, and RNA polymerase II (RNA Pol II ChIP-seq during T cell activation, we illustrate genome-wide temporal dynamics for ∼10,000 genes. This approach reveals not only immediate-early and posttranscriptionally regulated genes but also coupled changes in transcription and translation for >90% of genes. Recruitment, rather than release of paused RNA Pol II, primarily mediates transcriptional changes. This coincides with a genome-wide temporary slowdown in cotranscriptional splicing, even for polyadenylated mRNAs that are localized at the chromatin. Subsequent splicing optimization correlates with increasing Ser-2 phosphorylation of the RNA Pol II carboxy-terminal domain (CTD and activation of the positive transcription elongation factor (pTEFb. Thus, rapid de novo recruitment of RNA Pol II dictates the course of events during T cell activation, particularly transcription, splicing, and consequently translation. : Davari et al. visualize global changes in RNA Pol II binding, transcription, splicing, and translation. T cells change their functional program by rapid de novo recruitment of RNA Pol II and coupled changes in transcription and translation. This coincides with fluctuations in RNA Pol II phosphorylation and a temporary reduction in cotranscriptional splicing. Keywords: RNA Pol II, cotranscriptional splicing, T cell activation, ribosome profiling, 4sU, H3K36, Ser-5 RNA Pol II, Ser-2 RNA Pol II, immune response, immediate-early genes

Evaluating Water Use for Agricultural Intensification in Southern Amazonia Using the Water Footprint Sustainability Assessment

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Michael J. Lathuillière

2018-03-01

Full Text Available We performed a Water Footprint Sustainability Assessment (WFSA in the Xingu Basin of Mato Grosso (XBMT, Brazil, with the objectives of (1 tracking blue (as surface water and green water (as soil moisture regenerated by precipitation consumption in recent years (2000, 2014; and (2 evaluating agricultural intensification options for future years (2030, 2050 considering the effects of deforestation and climate change on water availability in the basin. The agricultural sector was the largest consumer of water in the basin despite there being almost no irrigation of cropland or pastures. In addition to water use by crops and pasture grass, water consumption attributed to cattle production included evaporation from roughly 9463 ha of small farm reservoirs used to provide drinking water for cattle in 2014. The WFSA showed that while blue and green water consumptive uses were within sustainable limits in 2014, deforestation, cattle confinement, and the use of irrigation to increase cropping frequency could drive water use to unsustainable levels in the future. While land management policies and practices should strive for protection of the remaining natural vegetation, increased agricultural production will require reservoir and irrigation water management to reduce the potential threat of blue water scarcity in the dry season. In addition to providing general guidance for future water allocation decisions in the basin, our study offers an interpretation of blue and green water scarcities with changes in land use and climate in a rapidly evolving agricultural frontier.

A rapid cosmic-ray increase in BC 3372-3371 from ancient buried tree rings in China.

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Wang, F Y; Yu, H; Zou, Y C; Dai, Z G; Cheng, K S

2017-11-14

Cosmic rays interact with the Earth's atmosphere to produce 14 C, which can be absorbed by trees. Therefore, rapid increases of 14 C in tree rings can be used to probe previous cosmic-ray events. By this method, three 14 C rapidly increasing events have been found. Plausible causes of these events include large solar proton events, supernovae, or short gamma-ray bursts. However, due to the lack of measurements of 14 C by year, the occurrence frequency of such 14 C rapidly increasing events is poorly known. In addition, rapid increases may be hidden in the IntCal13 data with five-year resolution. Here we report the result of 14 C measurements using an ancient buried tree during the period between BC 3388 and 3358. We found a rapid increase of about 9‰ in the 14 C content from BC 3372 to BC 3371. We suggest that this event could originate from a large solar proton event.

Pesticide acute toxicity is a better correlate of U.S. grassland bird declines than agricultural intensification.

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Pierre Mineau

Full Text Available Common agricultural birds are in decline, both in Europe and in North America. Evidence from Europe suggests that agricultural intensification and, for some species, the indirect effects of pesticides mediated through a loss of insect food resource is in part responsible. On a state-by-state basis for the conterminous Unites States (U.S., we looked at several agronomic variables to predict the number of grassland species increasing or declining according to breeding bird surveys conducted between 1980 and 2003. Best predictors of species declines were the lethal risk from insecticide use modeled from pesticide impact studies, followed by the loss of cropped pasture. Loss of permanent pasture or simple measures of agricultural intensification such as the proportion of land under crop or the proportion of farmland treated with herbicides did not explain bird declines as well. Because the proportion of farmland treated with insecticides, and more particularly the lethal risk to birds from the use of current insecticides feature so prominently in the best models, this suggests that, in the U.S. at least, pesticide toxicity to birds should be considered as an important factor in grassland bird declines.

Causes and consequences of mid–21st-century rapid ice loss events simulated by the Rossby centre regional atmosphere-ocean model

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Jean-Philippe Paquin

2013-08-01

Full Text Available Recent observations and modelling studies suggest that the Arctic climate is undergoing important transition. One manifestation of this change is seen in the rapid sea-ice cover decrease as experienced in 2007 and 2012. Although most numerical climate models cannot adequately reproduce the recent changes, some models produce similar Rapid Ice Loss Events (RILEs during the mid–21st-century. This study presents an analysis of four specific RILEs clustered around 2040 in three transient climate projections performed with the coupled Rossby Centre regional Atmosphere-Ocean model (RCAO. The analysis shows that long-term thinning causes increased vulnerability of the Arctic Ocean sea-ice cover. In the Atlantic sector, pre-conditioning (thinning of sea ice combined with anomalous atmospheric and oceanic heat transport causes large ice loss, while in the Pacific sector of the Arctic Ocean sea-ice albedo feedback appears important, particularly along the retreating sea-ice margin. Although maximum sea-ice loss occurs in the autumn, response in surface air temperature occurs in early winter, caused by strong increase in ocean-atmosphere surface energy fluxes, mainly the turbulent fluxes. Synchronicity of the events around 2040 in the projections is caused by a strong large-scale atmospheric circulation anomaly at the Atlantic lateral boundary of the regional model. The limited impact on land is caused by vertical propagation of the surface heat anomaly rather than horizontal, caused by the absence of low-level temperature inversion over the ocean.

Matrix Intensification Affects Body and Physiological Condition of Tropical Forest-Dependent Passerines.

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Justus P Deikumah

Full Text Available Matrix land-use intensification is a relatively recent and novel landscape change that can have important influences on the biota within adjacent habitat patches. While there are immediate local changes that it brings about, the influences on individual animals occupying adjacent habitats may be less evident initially. High-intensity land use could induce chronic stress in individuals in nearby remnants, leading ultimately to population declines. We investigated how physiological indicators and body condition measures of tropical forest-dependent birds differ between forest adjacent to surface mining sites and that near farmlands at two distances from remnant edge in southwest Ghana. We used mixed effects models of several condition indices including residual body mass and heterophil to lymphocyte (H/L ratios (an indicator of elevated chronic stress to explore the effect of matrix intensity on forest-dependent passerines classed as either sedentary area-sensitive habitat specialists or nomadic generalists. Individual birds occupying tropical forest remnants near surface mining sites were in poorer condition, as indicated by lower residual body mass and elevated chronic stress, compared to those in remnants near agricultural lands. The condition of the sedentary forest habitat specialists white-tailed alethe, Alethe diademata and western olive sunbird, Cyanomitra obscura was most negatively affected by high-intensity surface mining land-use adjacent to remnants, whereas generalist species were not affected. Land use intensification may set in train a new trajectory of faunal relaxation beyond that expected based on habitat loss alone. Patterns of individual condition may be useful in identifying habitats where species population declines may occur before faunal relaxation has concluded.

A Model of Rapid Radicalization Behavior Using Agent-Based Modeling and Quorum Sensing

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Schwartz, Noah; Drucker, Nick; Campbell, Kenyth

2012-01-01

Understanding the dynamics of radicalization, especially rapid radicalization, has become increasingly important to US policy in the past several years. Traditionally, radicalization is considered a slow process, but recent social and political events demonstrate that the process can occur quickly. Examining this rapid process, in real time, is impossible. However, recreating an event using modeling and simulation (M&S) allows researchers to study some of the complex dynamics associated with rapid radicalization. We propose to adapt the biological mechanism of quorum sensing as a tool to explore, or possibly explain, rapid radicalization. Due to the complex nature of quorum sensing, M&S allows us to examine events that we could not otherwise examine in real time. For this study, we employ Agent Based Modeling (ABM), an M&S paradigm suited to modeling group behavior. The result of this study was the successful creation of rapid radicalization using quorum sensing. The Battle of Mogadishu was the inspiration for this model and provided the testing conditions used to explore quorum sensing and the ideas behind rapid radicalization. The final product has wider applicability however, using quorum sensing as a possible tool for examining other catalytic rapid radicalization events.

Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc.

Science.gov (United States)

Chaillon, Antoine; Gianella, Sara; Lada, Steven M; Perez-Santiago, Josué; Jordan, Parris; Ignacio, Caroline; Karris, Maile; Richman, Douglas D; Mehta, Sanjay R; Little, Susan J; Wertheim, Joel O; Smith, Davey M

2018-02-01

Residual viremia is common during antiretroviral therapy (ART) and could be caused by ongoing low-level virus replication or by release of viral particles from infected cells. ART intensification should impact ongoing viral propagation but not virion release. Eighteen acutely infected men were enrolled in a randomized controlled trial and monitored for a median of 107 weeks. Participants started ART with ( n = 9) or without ( n = 9) intensification with maraviroc (MVC) within 90 days of infection. Levels of HIV DNA and cell-free RNA were quantified by droplet digital PCR. Deep sequencing of C2-V3 env , gag , and pol (454 Roche) was performed on longitudinally collected plasma and peripheral blood mononuclear cell (PBMC) samples while on ART. Sequence data were analyzed for evidence of evolution by (i) molecular diversity analysis, (ii) nonparametric test for panmixia, and (iii) tip date randomization within a Bayesian framework. There was a longitudinal decay of HIV DNA after initiation of ART with no difference between MVC intensification groups (-0.08 ± 0.01 versus -0.09 ± 0.01 log 10 copies/week in MVC + versus MVC - groups; P = 0.62). All participants had low-level residual viremia (median, 2.8 RNA copies/ml). Across participants, medians of 56 (interquartile range [IQR], 36 to 74), 29 (IQR, 25 to 35), and 40 (IQR, 31 to 54) haplotypes were generated for env , gag , and pol regions, respectively. There was no clear evidence of viral evolution during ART and no difference in viral diversity or population structure from individuals with or without MVC intensification. Further efforts focusing on elucidating the mechanism(s) of viral persistence in various compartments using recent sequencing technologies are still needed, and potential low-level viral replication should always be considered in cure strategies. IMPORTANCE Residual viremia is common among HIV-infected people on ART. It remains controversial if this viremia is a consequence of propagating

Major shifts in Amazon wildlife populations from recent intensification of floods and drought.

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Bodmer, Richard; Mayor, Pedro; Antunez, Miguel; Chota, Kimberlyn; Fang, Tula; Puertas, Pablo; Pittet, Marlini; Kirkland, Maire; Walkey, Mike; Rios, Claudia; Perez-Peña, Pedro; Henderson, Peter; Bodmer, William; Bicerra, Andy; Zegarra, Joseph; Docherty, Emma

2018-04-01

In the western Amazon Basin, recent intensification of river-level cycles has increased flooding during the wet seasons and decreased precipitation during the dry season. Greater than normal floods occurred in 2009 and in all years from 2011 to 2015 during high-water seasons, and a drought occurred during the 2010 low-water season. During these years, we surveyed populations of terrestrial, arboreal, and aquatic wildlife in a seasonally flooded Amazonian forest in the Loreto region of Peru (99,780 km 2 ) to study the effects of intensification of natural climatic fluctuations on wildlife populations and in turn effects on resource use by local people. Shifts in fish and terrestrial mammal populations occurred during consecutive years of high floods and the drought of 2010. As floods intensified, terrestrial mammal populations decreased by 95%. Fish, waterfowl, and otter (Pteronura brasiliensis) abundances increased during years of intensive floods, whereas river dolphin and caiman populations had stable abundances. Arboreal species, including, macaws, game birds, primates, felids, and other arboreal mammals had stable populations and were not affected directly by high floods. The drought of 2010 had the opposite effect: fish, waterfowl, and dolphin populations decreased, and populations of terrestrial and arboreal species remained stable. Ungulates and large rodents are important sources of food and income for local people, and large declines in these animals has shifted resource use of people living in the flooded forests away from hunting to a greater reliance on fish. © 2017 The Authors. Conservation Biology published by Wiley Periodicals, Inc. on behalf of Society for Conservation Biology.

Finite element analysis of the influence of elastic anisotropy on stress intensification at stress corrosion cracking initiation sites in fcc alloys

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Meric de Bellefon, G.; van Duysen, J. C.

2018-05-01

A recent finite-element method (FEM)-based study from the present authors quantified the effect of elastic anisotropy of grains on stress intensification at potential intergranular stress corrosion cracking (IGSCC) initiation sites in austenitic stainless steels. In particular, it showed that the auxetic behavior of grains (negative Poisson's ratio) in some directions plays a very important role in IGSCC initiation, since it can induce local stress intensification factors of about 1.6. A similar effect is expected for other fcc alloys such as Ni-based alloys. The present article confirms those results and paves the way to the definition of an IGSCC susceptibility index by identifying grain configurations that are the most favorable for crack initiation. The index will rely on the probability to get those configurations on surface of specimens.

The Role of Animals in Eco-functional Intensification of Organic Agriculture

DEFF Research Database (Denmark)

Vaarst, Mette

2015-01-01

Eco-functional intensification is understood as building synergies in multi-functional and resilient agricultural systems in harmony with their surrounding environment and human systems, to the benefit of diversified production of food and beyond, as in, for example, ecosystem services. Integration...... of animals into eco-functionally intensified agricultural systems to enhance agricultural, ecological and social systems, can contribute to driving a future sustainable development of organic agricultural and food systems. This approach may respond to challenges of an increasing industrialization...... to respond to current challenges in constantly changing environments, e.g., climate change. A necessary driver in transition towards more eco-functionally intensified agricultural and food systems is a governance system which protect the actors without a voice, e.g., ecosystems, pollinators, animals...

Results of antiretroviral treatment interruption and intensification in advanced multi-drug resistant HIV infection from the OPTIMA trial.

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Mark Holodniy

2011-03-01

Full Text Available Guidance is needed on best medical management for advanced HIV disease with multidrug resistance (MDR and limited retreatment options. We assessed two novel antiretroviral (ARV treatment approaches in this setting.We conducted a 2×2 factorial randomized open label controlled trial in patients with a CD4 count≤300 cells/µl who had ARV treatment (ART failure requiring retreatment, to two options (a re-treatment with either standard (≤4 ARVs or intensive (≥5 ARVs ART and b either treatment starting immediately or after a 12-week monitored ART interruption. Primary outcome was time to developing a first AIDS-defining event (ADE or death from any cause. Analysis was by intention to treat. From 2001 to 2006, 368 patients were randomized. At baseline, mean age was 48 years, 2% were women, median CD4 count was 106/µl, mean viral load was 4.74 log(10 copies/ml, and 59% had a prior AIDS diagnosis. Median follow-up was 4.0 years in 1249 person-years of observation. There were no statistically significant differences in the primary composite outcome of ADE or death between re-treatment options of standard versus intensive ART (hazard ratio 1.17; CI 0.86-1.59, or between immediate retreatment initiation versus interruption before re-treatment (hazard ratio 0.93; CI 0.68-1.30, or in the rate of non-HIV associated serious adverse events between re-treatment options.We did not observe clinical benefit or harm assessed by the primary outcome in this largest and longest trial exploring both ART interruption and intensification in advanced MDR HIV infection with poor retreatment options.Clinicaltrials.gov NCT00050089.

Microlensing observations rapid search for exoplanets: MORSE code for GPUs

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McDougall, Alistair; Albrow, Michael D.

2016-02-01

The rapid analysis of ongoing gravitational microlensing events has been integral to the successful detection and characterization of cool planets orbiting low-mass stars in the Galaxy. In this paper, we present an implementation of search and fit techniques on graphical processing unit (GPU) hardware. The method allows for the rapid identification of candidate planetary microlensing events and their subsequent follow-up for detailed characterization.

Impact de l'urbanisation sur l'intensification des systèmes de production horticoles au Cameroun

OpenAIRE

Temple, Ludovic; Minkoua Nzie, Jules René; Marquis, Sophie; Dury, Sandrine

2005-01-01

International audience; Impact of urbanization on the intensification of horticulture production systems in Cameroon. The urbanization of sub-Saharan African cities has resulted in an increase in food demand for horticultural productions (market gardening, plantains, yams...) and a modification of access conditions to productive resources (land, job, capital, inputs...). The extensive slash and burn production systems, which characterize food crop farming, are reaching the limit of their capa...

Can intensification reduce emission intensity of biofuel through optimized fertilizer use? Theory and the case of oil palm in Indonesia

NARCIS (Netherlands)

Noordwijk, van Meine; Khasanah, Nimatul; Dewi, Sonya

2017-01-01

Closing yield gaps through higher fertilizer use increases direct greenhouse gas emissions but shares the burden over a larger production volume. Net greenhouse gas (GHG) footprints per unit product under agricultural intensification vary depending on the context, scale and accounting method.

How smallholder farmers in Uttarakhand reworked the system of rice intensification: innovations from sociotechnical interactions in fields and villages

NARCIS (Netherlands)

Sen, D.

2015-01-01

The System of Rice Intensification (SRI) is presented in Asia and other parts of the world as an alternative ‘agro-ecological’ and ‘farm-based’ innovation in rice production. SRI calls for modifications in crop-management practices without relying on external inputs, which makes it different from

Process intensification characteristics of a microreactor absorber for enhanced CO_2 capture

International Nuclear Information System (INIS)

Ganapathy, Harish; Steinmayer, Sascha; Shooshtari, Amir; Dessiatoun, Serguei; Ohadi, Michael M.; Alshehhi, Mohamed

2016-01-01

Highlights: • Enhanced gas separation/CO_2 capture using aqueous DEA in micro-structured absorber. • 15 straight parallel channels with hydraulic diameter of 456 μm. • Achieved close to 100% absorption efficiency under certain operating conditions. • Mass transfer coefficients 1–3 orders of magnitude higher than conventional absorbers. • Substantial intensification of absorption process achievable using microreactors. - Abstract: Gas separation processes, including post-combustion carbon capture (PCCC) by chemical absorption using liquid solvents can be substantially enhanced using high performance micro-structured surfaces to enhance the surface area available for reaction. The present paper studies the hydrodynamics and mass transfer performance of gas–liquid absorption of CO_2 into aqueous diethanolamine in a micro-structured reactor. The system was designed to comprise 15 straight parallel channels in a cross flow inlet configuration. The hydraulic diameter of each channel was 456 μm. The performance of the reactor was studied with respect to the absorption efficiency, mass transfer coefficient, acid gas loading ratio, and pressure drop. A flow pattern map was developed using available regime transition criteria. Parametric studies varying the gas and liquid flow rates, as well as their respective concentrations at the reactor inlet, were conducted. The two-phase pressure drop was compared against the predictions of a piecewise model and a reasonably good agreement was obtained. Absorption efficiencies close to 100% were observed under certain operating conditions. The presently achieved values of liquid-side volumetric mass transfer coefficients were between 1–3 orders of magnitude higher than those reported for most conventional gas–liquid absorption systems, which can be attributed to the inherent high specific interfacial area provided through micro-structured surfaces. The results reported here indicate the substantial levels of process

Mechanisms and environmental factors that underlying the intensification of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy)-induced serotonin syndrome in rats

Science.gov (United States)

Tao, Rui; Shokry, Ibrahim M.; Callanan, John J.; Adams, H. Daniel; Ma, Zhiyuan

2014-01-01

Rationale Illicit use of MDMA (3,4-methylenedioxymethamphetamine; Ecstasy) may cause a mild or severe form of the serotonin syndrome. The syndrome intensity is not just influenced by drug doses but also by environmental factors. Objectives Warm environmental temperatures and physical activity are features of raves. The purpose of this study was to assess how these two factors can potentially intensify the syndrome. Methods Rats were administered MDMA at doses of 0.3, 1 or 3 mg/kg, and examined in the absence or presence of warm temperature and physical activity. The syndrome intensity was estimated by visual scoring for behavioral syndrome and also instrumentally measuring changes in symptoms of the syndrome. Results Our results showed that MDMA at 3 mg/kg, but not 0.3 or 1 mg/kg, caused a mild serotonin syndrome in rats. Each environmental factor alone moderately intensified the syndrome. When the two factors were combined, the intensification became more severe than each factor alone highlighting a synergistic effect. This intensification was blocked by the 5-HT2A receptor antagonist M100907, competitive NMDA receptor antagonist CGS19755, autonomic ganglionic blocker hexamethonium, and the benzodiazepine-GABAA receptor agonist midazolam, but not by the 5-HT1A receptor antagonist WAY100635 or nicotinic receptor antagonist methyllycaconitine. Conclusions Our data suggest that, in the absence of environmental factors, the MDMA-induced syndrome is mainly mediated through the serotonergic transmission (5HT-dependent mechanism), and therefore, is relatively mild. Warm temperature and physical activity facilitate serotonergic and other neural systems such as glutamatergic and autonomic transmissions, resulting in intensification of the syndrome (non-5HT mechanisms). PMID:25300903

Substorm topology in the ionosphere and magnetosphere during a flux rope event in the magnetotail

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O. Amm

2006-03-01

Full Text Available On 13 August 2002, at ~23:00 UT, about 10 min after a substorm intensification, Cluster observes a flux rope in the central magnetotail, followed by a localised fast flow event about oneminute later. Associated with the flux rope event, a traveling compression region (TCR is seen by those Cluster spacecraft which reside in the lobe. In the conjugate ionospheric region in Northern Scandinavia, the MIRACLE network observes the ionospheric equivalent currents, and the electron densities and electric fields are measured by the EISCAT radar along a meridional scanning profile. Further, the auroral evolution is observed with the Wideband Imaging Camera (WIC on the IMAGE satellite. We compare in detail the substorm evolution as observed in the ionosphere and in the magnetosphere, and examine whether topological correspondences to the flux rope event exist in the ionospheric signatures. The large-scale mapping of both the location and the direction of the flux rope to the ionosphere shows an excellent correspondence to a lens-shaped region of an auroral emission minimum. This region is bracketed by an auroral region equatorward of it which was preexisting to the substorm intensification, and a substorm-related auroral region poleward of it. It is characterised by reduced ionospheric conductances with respect to its environment, and downward field-aligned current (FAC observed both in the magnetosphere and in the ionosphere. As determined from the ionospheric data, this downward FAC area is moving eastward with a speed of ~2 km s-1, in good agreement with the mapped plasma bulk velocity measured at the Cluster satellite closest to that area. Further southwestward to this leading downward FAC area, a trailing upward FAC area is observed that moves eastward with the same speed. The direction of the ionospheric electric field permits a current closure between these two FAC areas through the ionosphere. We speculate that these FAC areas may correspond to

Insulin initiation and intensification in patients with T2DM for the primary care physician

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Unger J

2011-06-01

Full Text Available Jeff UngerCatalina Research Institute, Chino, CA, USAAbstract: Type 2 diabetes mellitus (T2DM is characterized by both insulin resistance and inadequate insulin secretion. All patients with the disease require treatment to achieve and maintain the target glycosylated hemoglobin (A1C level of 6.5%–7%. Pharmacological management of T2DM typically begins with the introduction of oral medications, and the majority of patients require exogenous insulin therapy at some point in time. Primary care physicians play an essential role in the management of T2DM since they often initiate insulin therapy and intensify regimens over time as needed. Although insulin therapy is prescribed on an individualized basis, treatment usually begins with basal insulin added to a background therapy of oral agents. Prandial insulin injections may be added if glycemic targets are not achieved. Treatments may be intensified over time using patient-friendly titration algorithms. The goal of insulin intensification within the primary care setting is to minimize patients' exposure to chronic hyperglycemia and weight gain, and reduce patients' risk of hypoglycemia, while achieving individualized fasting, postprandial, and A1C targets. Simplified treatment protocols and insulin delivery devices allow physicians to become efficient prescribers of insulin intensification within the primary care arena.Keywords: diabetes, basal, bolus, regimens, insulin analogs, structured glucose testing

The dream-lag effect: Selective processing of personally significant events during Rapid Eye Movement sleep, but not during Slow Wave Sleep.

Science.gov (United States)

van Rijn, E; Eichenlaub, J-B; Lewis, P A; Walker, M P; Gaskell, M G; Malinowski, J E; Blagrove, M

2015-07-01

Incorporation of details from waking life events into Rapid Eye Movement (REM) sleep dreams has been found to be highest on the night after, and then 5-7 nights after events (termed, respectively, the day-residue and dream-lag effects). In experiment 1, 44 participants kept a daily log for 10 days, reporting major daily activities (MDAs), personally significant events (PSEs), and major concerns (MCs). Dream reports were collected from REM and Slow Wave Sleep (SWS) in the laboratory, or from REM sleep at home. The dream-lag effect was found for the incorporation of PSEs into REM dreams collected at home, but not for MDAs or MCs. No dream-lag effect was found for SWS dreams, or for REM dreams collected in the lab after SWS awakenings earlier in the night. In experiment 2, the 44 participants recorded reports of their spontaneously recalled home dreams over the 10 nights following the instrumental awakenings night, which thus acted as a controlled stimulus with two salience levels, high (sleep lab) and low (home awakenings). The dream-lag effect was found for the incorporation into home dreams of references to the experience of being in the sleep laboratory, but only for participants who had reported concerns beforehand about being in the sleep laboratory. The delayed incorporation of events from daily life into dreams has been proposed to reflect REM sleep-dependent memory consolidation. However, an alternative emotion processing or emotional impact of events account, distinct from memory consolidation, is supported by the finding that SWS dreams do not evidence the dream-lag effect. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

Assessing the risk of impact of farming intensification on calcareous grasslands in Europe: a quantitative implementation of the MIRABEL framework

NARCIS (Netherlands)

Petit, S.; Elbersen, B.S.

2006-01-01

Intensification of farming practices is still a major driver of biodiversity loss in Europe, despite the implementation of policies that aim to reverse this trend. A conceptual framework called MIRABEL was previously developed that enabled a qualitative and expert-based assessment of the impact of

Rapid Active Power Control of Photovoltaic Systems for Grid Frequency Support

Energy Technology Data Exchange (ETDEWEB)

Hoke, Anderson; Shirazi, Mariko; Chakraborty, Sudipta; Muljadi, Eduard; Maksimovic, Dragan

2017-01-01

As deployment of power electronic coupled generation such as photovoltaic (PV) systems increases, grid operators have shown increasing interest in calling on inverter-coupled generation to help mitigate frequency contingency events by rapidly surging active power into the grid. When responding to contingency events, the faster the active power is provided, the more effective it may be for arresting the frequency event. This paper proposes a predictive PV inverter control method for very fast and accurate control of active power. This rapid active power control method will increase the effectiveness of various higher-level controls designed to mitigate grid frequency contingency events, including fast power-frequency droop, inertia emulation, and fast frequency response, without the need for energy storage. The rapid active power control method, coupled with a maximum power point estimation method, is implemented in a prototype PV inverter connected to a PV array. The prototype inverter's response to various frequency events is experimentally confirmed to be fast (beginning within 2 line cycles and completing within 4.5 line cycles of a severe test event) and accurate (below 2% steady-state error).

Increasing precipitation volatility in twenty-first-century California

Science.gov (United States)

Swain, Daniel L.; Langenbrunner, Baird; Neelin, J. David; Hall, Alex

2018-05-01

Mediterranean climate regimes are particularly susceptible to rapid shifts between drought and flood—of which, California's rapid transition from record multi-year dryness between 2012 and 2016 to extreme wetness during the 2016-2017 winter provides a dramatic example. Projected future changes in such dry-to-wet events, however, remain inadequately quantified, which we investigate here using the Community Earth System Model Large Ensemble of climate model simulations. Anthropogenic forcing is found to yield large twenty-first-century increases in the frequency of wet extremes, including a more than threefold increase in sub-seasonal events comparable to California's `Great Flood of 1862'. Smaller but statistically robust increases in dry extremes are also apparent. As a consequence, a 25% to 100% increase in extreme dry-to-wet precipitation events is projected, despite only modest changes in mean precipitation. Such hydrological cycle intensification would seriously challenge California's existing water storage, conveyance and flood control infrastructure.

Causal events enter awareness faster than non-causal events

Directory of Open Access Journals (Sweden)

Pieter Moors

2017-01-01

Full Text Available Philosophers have long argued that causality cannot be directly observed but requires a conscious inference (Hume, 1967. Albert Michotte however developed numerous visual phenomena in which people seemed to perceive causality akin to primary visual properties like colour or motion (Michotte, 1946. Michotte claimed that the perception of causality did not require a conscious, deliberate inference but, working over 70 years ago, he did not have access to the experimental methods to test this claim. Here we employ Continuous Flash Suppression (CFS—an interocular suppression technique to render stimuli invisible (Tsuchiya & Koch, 2005—to test whether causal events enter awareness faster than non-causal events. We presented observers with ‘causal’ and ‘non-causal’ events, and found consistent evidence that participants become aware of causal events more rapidly than non-causal events. Our results suggest that, whilst causality must be inferred from sensory evidence, this inference might be computed at low levels of perceptual processing, and does not depend on a deliberative conscious evaluation of the stimulus. This work therefore supports Michotte’s contention that, like colour or motion, causality is an immediate property of our perception of the world.

Energy Flow and Rapidity Gaps Between Jets in Photoproduction at HERA

CERN Document Server

Adloff, C.; Andrieu, B.; Anthonis, T.; Arkadov, V.; Astvatsatourov, A.; Babaev, A.; Bahr, J.; Baranov, P.; Barrelet, E.; Bartel, W.; Bate, P.; Becker, J.; Beglarian, A.; Behnke, O.; Beier, C.; Belousov, A.; Benisch, T.; Berger, C.; Berndt, T.; Bizot, J.C.; Boehme, J.; Boudry, V.; Braunschweig, W.; Brisson, V.; Broker, H.B.; Brown, D.P.; Bruckner, W.; Bruncko, D.; Burger, J.; Busser, F.W.; Bunyatyan, A.; Burrage, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Cao, Jun; Caron, S.; Cassol-Brunner, F.; Clarke, D.; Collard, C.; Contreras, J.G.; Coppens, Y.R.; Coughlan, J.A.; Cousinou, M.C.; Cox, B.E.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Dau, W.D.; Daum, K.; Davidsson, M.; Delcourt, B.; Delerue, N.; Demirchyan, R.; De Roeck, A.; De Wolf, E.A.; Diaconu, C.; Dingfelder, J.; Dixon, P.; Dodonov, V.; Dowell, J.D.; Droutskoi, A.; Dubak, A.; Duprel, C.; Eckerlin, Guenter; Eckstein, D.; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellerbrock, M.; Elsen, E.; Erdmann, M.; Erdmann, W.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Ferencei, J.; Ferron, S.; Fleischer, M.; Fleming, Y.H.; Flugge, G.; Fomenko, A.; Foresti, I.; Formanek, J.; Franke, G.; Gabathuler, E.; Gabathuler, K.; Garvey, J.; Gassner, J.; Gayler, Joerg; Gerhards, R.; Gerlich, C.; Ghazaryan, Samvel; Goerlich, L.; Gogitidze, N.; Grab, C.; Grassler, H.; Greenshaw, T.; Grindhammer, Guenter; Hadig, T.; Haidt, D.; Hajduk, L.; Haller, J.; Haynes, W.J.; Heinemann, B.; Heinzelmann, G.; Henderson, R.C.W.; Hengstmann, S.; Henschel, H.; Heremans, R.; Herrera, G.; Herynek, I.; Hildebrandt, M.; Hilgers, M.; Hiller, K.H.; Hladky, J.; Hoting, P.; Hoffmann, D.; Horisberger, R.; Hurling, S.; Ibbotson, M.; Issever, C .; Jacquet, M.; Jaffre, M.; Janauschek, L.; Janssen, X.; Jemanov, V.; Jonsson, L.; Johnson, C.; Johnson, D.P.; Jones, M.A.S.; Jung, H.; Kant, D.; Kapichine, M.; Karlsson, M.; Karschnick, O.; Keil, F.; Keller, N.; Kennedy, J.; Kenyon, I.R.; Kermiche, S.; Kiesling, Christian M.; Kjellberg, P.; Klein, M.; Kleinwort, C.; Kluge, T.; Knies, G.; Koblitz, B.; Kolya, S.D.; Korbel, V.; Kostka, P.; Kotelnikov, S.K.; Koutouev, R.; Koutov, A.; Krehbiel, H.; Kroseberg, J.; Kruger, K.; Kupper, A.; Kuhr, T.; Kurca, T.; Lamb, D.; Landon, M.P.J.; Lange, W.; Lastovicka, T.; Laycock, P.; Lebailly, E.; Lebedev, A.; Leissner, B.; Lemrani, R.; Lendermann, V.; Levonian, S.; Lindstroem, M.; List, B.; Lobodzinska, E.; Lobodzinski, B.; Loginov, A.; Loktionova, N.; Lubimov, V.; Luders, S.; Luke, D.; Lytkin, L.; Mahlke-Kruger, H.; Malden, N.; Malinovski, E.; Malinovski, I.; Maracek, R.; Marage, P.; Marks, J.; Marshall, R.; Martyn, H.U.; Martyniak, J.; Maxfield, S.J.; Meer, D.; Mehta, A.; Meier, K.; Meyer, A.B.; Meyer, H.; Meyer, J.; Meyer, P.O.; Mikocki, S.; Milstead, D.; Mkrtchyan, T.; Mohr, R.; Mohrdieck, S.; Mondragon, M.N.; Moreau, F.; Morozov, A.; Morris, J.V.; Muller, K.; Murin, P.; Nagovizin, V.; Naroska, B.; Naumann, J.; Naumann, T.; Nellen, G.; Newman, Paul R.; Nicholls, T.C.; Niebergall, F.; Niebuhr, C.; Nix, O.; Nowak, G.; Olsson, J.E.; Ozerov, D.; Panassik, V.; Pascaud, C.; Patel, G.D.; Peez, M.; Perez, E.; Phillips, J.P.; Pitzl, D.; Poschl, R.; Potachnikova, I.; Povh, B.; Radel, G.; Rauschenberger, J.; Reimer, P.; Reisert, B.; Reyna, D.; Risler, C.; Rizvi, E.; Robmann, P.; Roosen, R.; Rostovtsev, A.; Rusakov, S.; Rybicki, K.; Sankey, D.P.C.; Schatzel, S.; Scheins, J.; Schilling, F.P.; Schleper, P.; Schmidt, D.; Schmidt, S.; Schmitt, S.; Schneider, M.; Schoeffel, L.; Schoning, A.; Schorner, T.; Schroder, V.; Schultz-Coulon, H.C.; Schwanenberger, C.; Sedlak, K.; Sefkow, F.; Chekelian, V.; Sheviakov, I.; Shtarkov, L.N.; Sirois, Y.; Sloan, T.; Smirnov, P.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, Arnd E.; Spitzer, H.; Stamen, R.; Stella, B.; Stiewe, J.; Straumann, U.; Swart, M.; Tasevsky, M.; Tchetchelnitski, S.; Thompson, Graham; Thompson, P.D.; Tobien, N.; Traynor, D.; Truoel, Peter; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Turney, J.E.; Tzamariudaki, E.; Udluft, S.; Urban, Marcel; Usik, A.; Valkar, S.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Vassiliev, S.; Vazdik, Y.; Vichnevski, A.; Wacker, K.; Wagner, J.; Wallny, R.; Waugh, B.; Weber, G.; Weber, M.; Wegener, D.; Werner, C.; Werner, M.; Werner, N.; Wessels, M.; White, G.; Wiesand, S.; Wilksen, T.; Winde, M.; Winter, G.G.; Wissing, C.; Wobisch, M.; Woehrling, E.E.; Wunsch, E.; Wyatt, A.C.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhokin, A.; Zomer, F.; zur Nedden, M.

2002-01-01

Dijet events in photon-proton collisions in which there is a large pseudorapidity separation Delta eta > 2.5 between the two highest E_T jets are studied with the H1 detector at HERA. The inclusive dijet cross sections are measured as functions of the longitudinal momentum fractions of the proton and photon which participate in the production of the jets, x_pjet and x_gjet respectively, Delta eta, the pseudorapidity separation between the two highest E_T jets, and E_T^gap, the total summed transverse energy between the jets. Rapidity gap events are defined as events in which E_T^gap is less than E_T^cut, for E_T^cut varied between 0.5 and 2.0 GeV. The fraction of dijet events with a rapidity gap is measured differentially in Delta eta, x_pjet and x_gjet. An excess of events with rapidity gaps at low values of E_T^cut is observed above the expectation from standard photoproduction processes. This excess can be explained by the exchange of a strongly interacting colour singlet object between the jets.

Extinction Events Can Accelerate Evolution

DEFF Research Database (Denmark)

Lehman, Joel; Miikkulainen, Risto

2015-01-01

Extinction events impact the trajectory of biological evolution significantly. They are often viewed as upheavals to the evolutionary process. In contrast, this paper supports the hypothesis that although they are unpredictably destructive, extinction events may in the long term accelerate...... evolution by increasing evolvability. In particular, if extinction events extinguish indiscriminately many ways of life, indirectly they may select for the ability to expand rapidly through vacated niches. Lineages with such an ability are more likely to persist through multiple extinctions. Lending...... computational support for this hypothesis, this paper shows how increased evolvability will result from simulated extinction events in two computational models of evolved behavior. The conclusion is that although they are destructive in the short term, extinction events may make evolution more prolific...

Rapid, generalized adaptation to asynchronous audiovisual speech.

Science.gov (United States)

Van der Burg, Erik; Goodbourn, Patrick T

2015-04-07

The brain is adaptive. The speed of propagation through air, and of low-level sensory processing, differs markedly between auditory and visual stimuli; yet the brain can adapt to compensate for the resulting cross-modal delays. Studies investigating temporal recalibration to audiovisual speech have used prolonged adaptation procedures, suggesting that adaptation is sluggish. Here, we show that adaptation to asynchronous audiovisual speech occurs rapidly. Participants viewed a brief clip of an actor pronouncing a single syllable. The voice was either advanced or delayed relative to the corresponding lip movements, and participants were asked to make a synchrony judgement. Although we did not use an explicit adaptation procedure, we demonstrate rapid recalibration based on a single audiovisual event. We find that the point of subjective simultaneity on each trial is highly contingent upon the modality order of the preceding trial. We find compelling evidence that rapid recalibration generalizes across different stimuli, and different actors. Finally, we demonstrate that rapid recalibration occurs even when auditory and visual events clearly belong to different actors. These results suggest that rapid temporal recalibration to audiovisual speech is primarily mediated by basic temporal factors, rather than higher-order factors such as perceived simultaneity and source identity. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Increasing crop production in Russia and Ukraine—regional and global impacts from intensification and recultivation

Science.gov (United States)

Deppermann, Andre; Balkovič, Juraj; Bundle, Sophie-Charlotte; Di Fulvio, Fulvio; Havlik, Petr; Leclère, David; Lesiv, Myroslava; Prishchepov, Alexander V.; Schepaschenko, Dmitry

2018-02-01

Russia and Ukraine are countries with relatively large untapped agricultural potentials, both in terms of abandoned agricultural land and substantial yield gaps. Here we present a comprehensive assessment of Russian and Ukrainian crop production potentials and we analyze possible impacts of their future utilization, on a regional as well as global scale. To this end, the total amount of available abandoned land and potential yields in Russia and Ukraine are estimated and explicitly implemented in an economic agricultural sector model. We find that cereal (barley, corn, and wheat) production in Russia and Ukraine could increase by up to 64% in 2030 to 267 million tons, compared to a baseline scenario. Oilseeds (rapeseed, soybean, and sunflower) production could increase by 84% to 50 million tons, respectively. In comparison to the baseline, common net exports of Ukraine and Russia could increase by up to 86.3 million tons of cereals and 18.9 million tons of oilseeds in 2030, representing 4% and 3.6% of the global production of these crops, respectively. Furthermore, we find that production potentials due to intensification are ten times larger than potentials due to recultivation of abandoned land. Consequently, we also find stronger impacts from intensification at the global scale. A utilization of crop production potentials in Russia and Ukraine could globally save up to 21 million hectares of cropland and reduce average global crop prices by more than 3%.

Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment.

Science.gov (United States)

Wagner, Jessica; Kline, C Leah; Zhou, Lanlan; Campbell, Kerry S; MacFarlane, Alexander W; Olszanski, Anthony J; Cai, Kathy Q; Hensley, Harvey H; Ross, Eric A; Ralff, Marie D; Zloza, Andrew; Chesson, Charles B; Newman, Jenna H; Kaufman, Howard; Bertino, Joseph; Stein, Mark; El-Deiry, Wafik S

2018-06-01

ONC201 is a first-in-class, orally active antitumor agent that upregulates cytotoxic TRAIL pathway signaling in cancer cells. ONC201 has demonstrated safety and preliminary efficacy in a first-in-human trial in which patients were dosed every 3 weeks. We hypothesized that dose intensification of ONC201 may impact antitumor efficacy. We discovered that ONC201 exerts dose- and schedule-dependent effects on tumor progression and cell death signaling in vivo. With dose intensification, we note a potent anti-metastasis effect and inhibition of cancer cell migration and invasion. Our preclinical results prompted a change in ONC201 dosing in all open clinical trials. We observed accumulation of activated NK+ and CD3+ cells within ONC201-treated tumors and that NK cell depletion inhibits ONC201 efficacy in vivo, including against TRAIL/ONC201-resistant Bax-/- tumors. Immunocompetent NCR1-GFP mice, in which NK cells express GFP, demonstrated GFP+ NK cell infiltration of syngeneic MC38 colorectal tumors. Activation of primary human NK cells and increased degranulation occurred in response to ONC201. Coculture experiments identified a role for TRAIL in human NK-mediated antitumor cytotoxicity. Preclinical results indicate the potential utility for ONC201 plus anti-PD-1 therapy. We observed an increase in activated TRAIL-secreting NK cells in the peripheral blood of patients after ONC201 treatment. The results offer what we believe to be a unique pathway of immune stimulation for cancer therapy.

ANALISIS KAWASAN POTENSIAL UNTUK TAMBAK SUPER-INTENSIF DI PESISIR KABUPATEN BARRU PROVINSI SULAWESI SELATAN

Directory of Open Access Journals (Sweden)

Hasnawi Hasnawi

2016-12-01

Full Text Available Tambak teknologi super-intensif tidak memerlukan lahan budidaya yang luas, produksi yang tinggi dimungkinkan dengan padat tebar tinggi dan input teknologi. Keberhasilan teknologi ini sangat ditentukan oleh lokasi budidaya yang tepat, infrastruktur yang memadai dan memenuhi standar, dilengkapi instalasi pengolahan air limbah (IPAL, serta dukungan faktor sosial yang menjadi penentu penerapan dan keberlanjutannya. Penelitian ini bertujuan untuk menentukan lokasi potensial pengembangan tambak super-intensif di kawasan pesisir Kabupaten Barru Provinsi Sulawesi Selatan. Pada tahap awal, kawasan pesisir yang potensial diidentifikasi melalui analisis elevasi lahan dari citra satelit Aster GDEM dan penggunaan lahan dari data Google Earth. Selanjutnya faktor sosial berupa potensi konflik dengan penggunaan lahan saat ini menjadi data awal yang dikumpulkan sebelum dilakukan pengukuran variabel lain. Variabel yang diobservasi langsung antara lain; elevasi lahan, tekstur tanah, ketersediaan infrastruktur pendukung, pasang surut, penggunaan lahan saat ini, dan kualitas perairan dilakukan di sekitar lokasi potensial terpilih. Analisis data dilakukan dengan mengaplikasikan sistem informasi geografis (SIG. Hasil penelitian menunjukkan bahwa lokasi potensial dijumpai di Desa Pancana Kecamatan Tanete Rilau dengan luas kawasan sekitar 17,5 ha. Variabel yang diidentifikasi menjadi pembatas utama untuk pengembangan tambak super-intensif di kawasan tersebut adalah elevasi lahan dan keberadaan potensi konflik dengan penggunaan lahan saat ini. A super-intensive pond technology does not require extensive land cultivation, however the high production is expected from its ability to increase stocking density particularly for vannamei species. The success of this technology is highly depend upon proper site selection, availability of supporting infrastructure, the availability of wastewater treatment plant (WWTP, and supporting of social factor determining the implementation

Analysis of the structure of events by the method of rapidity intervals in K-p interactions at 32 GeV/c and pp interactions at 69 GeV/c

International Nuclear Information System (INIS)

Babintsev, V.V.; Bumazhnov, V.A.; Kruglov, N.A.; Moiseev, A.M.; Proskuryakov, A.S.; Smirnova, L.N.; Ukhanov, M.N.

1981-01-01

We present an analysis of the structure of distributions in the magnitude r/sup n//sub m/ of rapidity intervals containing m charged particles in events with n charged particles in K - p interactions at 32 GeV/c and pp interactions at 69 GeV/c. It is found that all distributions correspond to a smooth curve with a single maximum. A comparison is made between the shape of the experimental distributions for K - p interactions and the shape of the distributions for generated events corresponding to the multi-Regge model

Influence of management and environment on Australian wheat: information for sustainable intensification and closing yield gaps

Science.gov (United States)

Bryan, B. A.; King, D.; Zhao, G.

2014-04-01

In the future, agriculture will need to produce more, from less land, more sustainably. But currently, in many places, actual crop yields are below those attainable. We quantified the ability for agricultural management to increase wheat yields across 179 Mha of potentially arable land in Australia. Using the Agricultural Production Systems Simulator (APSIM), we simulated the impact on wheat yield of 225 fertilization and residue management scenarios at a high spatial, temporal, and agronomic resolution from 1900 to 2010. The influence of management and environmental variables on wheat yield was then assessed using Spearman’s non-parametric correlation test with bootstrapping. While residue management showed little correlation, fertilization strongly increased wheat yield up to around 100 kg N ha-1 yr-1. However, this effect was highly dependent on the key environment variables of rainfall, temperature, and soil water holding capacity. The influence of fertilization on yield was stronger in cooler, wetter climates, and in soils with greater water holding capacity. We conclude that the effectiveness of management intensification to increase wheat yield is highly dependent upon local climate and soil conditions. We provide context-specific information on the yield benefits of fertilization to support adaptive agronomic decision-making and contribute to the closure of yield gaps. We also suggest that future assessments consider the economic and environmental sustainability of management intensification for closing yield gaps.

Intensification of esterification of non edible oil as sustainable feedstock using cavitational reactors.

Science.gov (United States)

Mohod, Ashish V; Subudhi, Abhijeet S; Gogate, Parag R

2017-05-01

Using sustainable feed stock such as non-edible oil for the biodiesel production can be one of the cost effective approaches considering the ever growing interest towards renewable energy and problems in existing approaches for production. However, due to the high free fatty acid content, non-edible oils require considerable preprocessing before the actual transesterification reaction for biodiesel production. The present work focuses on intensification of the esterification reaction used as preprocessing step based on acoustic and hydrodynamic cavitation also presenting the comparison with the conventional approach. Karanja oil with initial acid value as 14.15mg of KOH/g of oil has been used as a sustainable feedstock. Effect of operating parameters such as molar ratio, catalyst loading, temperature and type of catalyst (sulfuric acid and Amberlyst-15) on the acid value reduction has been investigated. The maximum reduction in the acid value (final acid value as 2.7mg of KOH/g of oil) was obtained using acoustic cavitation at optimum molar ratio of oil to methanol as 1:5 and 2% sulfuric acid loading at ambient temperature. In the case of hydrodynamic cavitation, acid value reduced upto 4.2mg of KOH under optimized conditions of first stage processing. In the second stage esterification using hydrodynamic cavitation and conventional approach, the final acid value was 3.6 and 3.8mg of KOH/g of oil respectively. Energy requirement analysis for ultrasound and conventional approaches clearly established the superiority of the ultrasound based approach. The present study clearly demonstrated that significant intensification benefits can be obtained in terms of the reduction in the molar ratio and operating temperature for the case of acoustic cavitation as compared to the conventional approach with somewhat lower effects for the hydrodynamic cavitation. Copyright © 2016 Elsevier B.V. All rights reserved.

Relative contributions of synoptic and intraseasonal variations to strong cold events over eastern China

Science.gov (United States)

Song, Lei; Wu, Renguang; Jiao, Yang

2018-06-01

The present study investigates the relative roles of intraseasonal oscillations (ISOs) and synoptic variations in strong cold events over eastern China during the boreal winter. The ISOs and synoptic variations explain about 55% and 20% of the total area-mean temperature anomaly in eastern China, respectively. The advection of synoptic winds on synoptic temperature gradients has a leading contribution to the temperature decrease before the cold events and thus the synoptic variations are important in determining the time of peak cold anomalies. The ISOs have a larger role in sustaining the cold events. The height anomalies associated with ISOs and synoptic variations are manifested as Rossby wave trains propagating along the polar front jet over the Eurasian continent before the cold events. They both contribute to the deepening of the East Asian trough and the development of cold events. Compared to the ISO wave train, the synoptic wave train has a smaller spatial scale and moves faster. There are obvious intraseasonal signals in the stratosphere about 1 week before the cold events over eastern China. Large negative height anomalies associated with the weakening of the polar vortex are observed over the North Atlantic. These anomalies move eastwards and propagate downwards after reaching the west coast of Europe. The downward moving stratospheric signal triggers height anomalies in the troposphere over the entrance region of the polar front jet. Then the anomalies propagate towards East Asia along the wave train, contributing to the intensification of the Siberian high and the East Asian trough and the occurrence of cold events over eastern China.

Sustainable intensification in agricultural systems

Science.gov (United States)

Pretty, Jules; Bharucha, Zareen Pervez

2014-01-01

Background Agricultural systems are amended ecosystems with a variety of properties. Modern agroecosystems have tended towards high through-flow systems, with energy supplied by fossil fuels directed out of the system (either deliberately for harvests or accidentally through side effects). In the coming decades, resource constraints over water, soil, biodiversity and land will affect agricultural systems. Sustainable agroecosystems are those tending to have a positive impact on natural, social and human capital, while unsustainable systems feed back to deplete these assets, leaving fewer for the future. Sustainable intensification (SI) is defined as a process or system where agricultural yields are increased without adverse environmental impact and without the conversion of additional non-agricultural land. The concept does not articulate or privilege any particular vision or method of agricultural production. Rather, it emphasizes ends rather than means, and does not pre-determine technologies, species mix or particular design components. The combination of the terms ‘sustainable’ and ‘intensification’ is an attempt to indicate that desirable outcomes around both more food and improved environmental goods and services could be achieved by a variety of means. Nonetheless, it remains controversial to some. Scope and Conclusions This review analyses recent evidence of the impacts of SI in both developing and industrialized countries, and demonstrates that both yield and natural capital dividends can occur. The review begins with analysis of the emergence of combined agricultural–environmental systems, the environmental and social outcomes of recent agricultural revolutions, and analyses the challenges for food production this century as populations grow and consumption patterns change. Emergent criticisms are highlighted, and the positive impacts of SI on food outputs and renewable capital assets detailed. It concludes with observations on policies and

The High Altitude MMIC Sounding Radiometer on the GLOBAL HAWK: From Technology Development to Science Discovery

Science.gov (United States)

Brown, Shannon; Denning, Richard; Lambrigtsen, Bjorn; Lim, Boon; Tanabe, Jordan; Tanner, Alan

2013-01-01

This paper presents results from the High Altitude MMIC Sounding Radiometer (HAMSR) during three recent field campaigns on the Global Hawk Unmanned Ariel Vehicles (UAV), focusing on the enabling technology that led to unprecedented observations of significant weather phenomenon, such as thermodynamic evolution of the tropical cyclone core during rapid intensification and the high resolution three dimensional mapping of several atmospheric river events. HAMSR is a 25 channel cross-track scanning microwave sounder with channels near the 60 and 118 GHz oxygen lines and the 183 GHz water vapor line. HAMSR was originally designed and built at the Jet Propulsion Laboratory as a technology demonstrator in 1998. Subsequent to this, HAMSR participated in three NASA hurricane field campaigns, CAMEX-4, TCSP and NAMMA. Beginning in 2008, HAMSR was extensively upgraded to deploy on the NASA Global Hawk (GH) platform and serve as an asset to the NASA sub-orbital program. HAMSR has participated on the Global Hawk during the 2010 Genesis and Rapid Intensification (GRIP) campaign, the 2011 Winter Storms and Atmospheric Rivers (WISPAR) campaign and is currently participating in the NASA Ventures Hurricane and Severe Storm Sentinel (HS3) campaign (2011-2015).

Utilization of organic fertilizer to increase paddy growth and productivity using System of Rice Intensification (SRI method in saline soil

Directory of Open Access Journals (Sweden)

V . O . Subardja

2016-01-01

Full Text Available Soil salinity has negative effect on soil biodiversity as well as microbial activities. Hence, rice growth also effected by salinity. Application of organic fertilizer and adoption of System of Rice Intensification (SRI cultivation might improve the (biological soil properties and increase rice yield. The aim of this study was to evaluate the effect of two different rice cultivation methods namely conventional rice cultivation method and System of Rice Intensification (SRI rice cultivation method and two kinds organic fertilizer on improvement of soil biological properties and rice yield. In this study, a split plot experimental design was applied where rice cultivation method (conventional and SRI was the main plot and two kinds of organic fertilizer (market waste and rice straw was the sub plot. The treatments had four replicates. The results showed that SRI cultivation with market waste organic fertilizer could increase soil biological properties (population of microbe, fungi and soil respiration. The same treatment also increased rice growth and production. Combination of SRI and market waste organic fertilizer yielded the highest rice production (7.21 t/ha.

Clan structure analysis and rapidity gap probability

International Nuclear Information System (INIS)

Lupia, S.; Giovannini, A.; Ugoccioni, R.

1995-01-01

Clan structure analysis in rapidity intervals is generalized from negative binomial multiplicity distribution to the wide class of compound Poisson distributions. The link of generalized clan structure analysis with correlation functions is also established. These theoretical results are then applied to minimum bias events and evidentiate new interesting features, which can be inspiring and useful in order to discuss data on rapidity gap probability at TEVATRON and HERA. (orig.)

Clan structure analysis and rapidity gap probability

Energy Technology Data Exchange (ETDEWEB)

Lupia, S. [Turin Univ. (Italy). Ist. di Fisica Teorica]|[Istituto Nazionale di Fisica Nucleare, Turin (Italy); Giovannini, A. [Turin Univ. (Italy). Ist. di Fisica Teorica]|[Istituto Nazionale di Fisica Nucleare, Turin (Italy); Ugoccioni, R. [Turin Univ. (Italy). Ist. di Fisica Teorica]|[Istituto Nazionale di Fisica Nucleare, Turin (Italy)

1995-03-01

Clan structure analysis in rapidity intervals is generalized from negative binomial multiplicity distribution to the wide class of compound Poisson distributions. The link of generalized clan structure analysis with correlation functions is also established. These theoretical results are then applied to minimum bias events and evidentiate new interesting features, which can be inspiring and useful in order to discuss data on rapidity gap probability at TEVATRON and HERA. (orig.)

Penggunaan Skor Pediatric Logistic Organ Dysfunction Harian sebagai Prediktor Mortalitas Anak yang Dirawat di Unit Perawatan Intensif Anak

OpenAIRE

Hendra Salim; Suparyatha I B; Budi-Hartawan I Nym

2016-01-01

Latar belakang. Penggunaan sistem skoring Pediatric Logistic Organ Dysfunction (PELOD) sebagai prediktor mortalitas anak yang dirawat di Unit Perawatan Intensif Anak (UPIA) di Indonesia masih belum banyak diteliti. Tujuan. Mengetahui hubungan skor PELOD harian dalam memprediksi mortalitas anak yang dirawat di UPIA. Metode. Penelitian observasional analitik terhadap 49 anak yang dirawat di UPIA bulan Maret-Juli 2012. Skor PELOD harian dinilai selama satu minggu pertama perawatan dan diba...

Comparing decision-support systems in adopting sustainable intensification criteria

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Bouda eVosough Ahmadi

2015-02-01

Full Text Available Sustainable intensification (SI is a multifaceted concept incorporating the ambition to increase or maintain the current level of agricultural yields while reduce negative ecological and environmental impacts. Decision-support systems (DSS that use integrated analytical methods are often used to support decision making processes in agriculture. However, DSS often consist of set of values, objectives and assumptions that may be inconsistent or in conflict with merits and objectives of SI. These potential conflicts will have consequences for adoption and up-take of agricultural research, technologies and related policies and regulations such as genetic technology in pursuit of SI. This perspective paper aimed at comparing a number of frequently used socio-economic DSS with respect to their capacity in incorporating various dimensions of SI, and discussing their application to analyzing farm animal genetic resources (FAnGR policies. The case of FAnGR policies was chosen because of its great potential in delivering merits of SI. It was concluded that flexible DSS, with great integration capacity with various natural and social sciences, are needed to provide guidance on feasibility, practicality and policy implementation for SI.

Sustainable intensification: a multifaceted, systemic approach to international development.

Science.gov (United States)

Himmelstein, Jennifer; Ares, Adrian; van Houweling, Emily

2016-12-01

Sustainable intensification (SI) is a term increasingly used to describe a type of approach applied to international agricultural projects. Despite its widespread use, there is still little understanding or knowledge of the various facets of this composite paradigm. A review of the literature has led to the formalization of three principles that convey the current characterization of SI, comprising a whole system, participatory, agroecological approach. Specific examples of potential bottlenecks to the SI approach are cited, in addition to various technologies and techniques that can be applied to overcome these obstacles. Models of similar, succcessful approaches to agricultural development are examined, along with higher level processes. Additionally, this review explores the desired end points of SI and argues for the inclusion of gender and nutrition throughout the process. To properly apply the SI approach, its various aspects need to be understood and adapted to different cultural and geographic situations. New modeling systems and examples of the effective execution of SI strategies can assist with the successful application of the SI paradigm within complex developing communities. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Influence of management and environment on Australian wheat: information for sustainable intensification and closing yield gaps

International Nuclear Information System (INIS)

Bryan, B A; King, D; Zhao, G

2014-01-01

In the future, agriculture will need to produce more, from less land, more sustainably. But currently, in many places, actual crop yields are below those attainable. We quantified the ability for agricultural management to increase wheat yields across 179 Mha of potentially arable land in Australia. Using the Agricultural Production Systems Simulator (APSIM), we simulated the impact on wheat yield of 225 fertilization and residue management scenarios at a high spatial, temporal, and agronomic resolution from 1900 to 2010. The influence of management and environmental variables on wheat yield was then assessed using Spearman’s non-parametric correlation test with bootstrapping. While residue management showed little correlation, fertilization strongly increased wheat yield up to around 100 kg N ha −1  yr −1 . However, this effect was highly dependent on the key environment variables of rainfall, temperature, and soil water holding capacity. The influence of fertilization on yield was stronger in cooler, wetter climates, and in soils with greater water holding capacity. We conclude that the effectiveness of management intensification to increase wheat yield is highly dependent upon local climate and soil conditions. We provide context-specific information on the yield benefits of fertilization to support adaptive agronomic decision-making and contribute to the closure of yield gaps. We also suggest that future assessments consider the economic and environmental sustainability of management intensification for closing yield gaps. (paper)

The new capitalist philanthropy and the intensification of the teacher’s work: reflections on corporate volunteering

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Maria Vieira Silva

2012-01-01

Full Text Available This paper summarizes research results obtained by the authors on the new formats of capitalist philanthropy through volunteering work. It highlights, especially,teaching practices developed in companies with “social responsibility”, consolidating a new modality of teacher’s work. From speeches of company managers and volunteer teachers, the analyses contextualize the paradoxes, contradictions, and ambiguities found in volunteering activities, catching the processes of work intensification observed in the set of devices provided by the capitalist administration, which focus on the subjective dimensions of the worker and the objective dimensions of capital accumulation.

Effects of ecological and conventional agricultural intensification practices on maize yields in sub-Saharan Africa under potential climate change

International Nuclear Information System (INIS)

Folberth, Christian; Yang, Hong; Gaiser, Thomas; Liu, Junguo; Wang, Xiuying; Williams, Jimmy; Schulin, Rainer

2014-01-01

Much of Africa is among the world’s regions with lowest yields in staple food crops, and climate change is expected to make it more difficult to catch up in crop production in particular in the long run. Various agronomic measures have been proposed for lifting agricultural production in Africa and to adapt it to climate change. Here, we present a projection of potential climate change impacts on maize yields under different intensification options in Sub-Saharan Africa (SSA) using an agronomic model, GIS-based EPIC (GEPIC). Fallow and nutrient management options taken into account are (a) conventional intensification with high mineral N supply and a bare fallow, (b) moderate mineral N supply and cowpea rotation, and (c) moderate mineral N supply and rotation with a fast growing N fixing tree Sesbania sesban. The simulations suggest that until the 2040s rotation with Sesbania will lead to an increase in yields due to increasing N supply besides improving water infiltration and soils’ water holding capacity. Intensive cultivation with a bare fallow or an herbaceous crop like cowpea in the rotation is predicted to result in lower yields and increased soil erosion during the same time span. However, yields are projected to decrease in all management scenarios towards the end of the century, should temperature increase beyond critical thresholds. The results suggest that the effect of eco-intensification as a sole means of adapting agriculture to climate change is limited in Sub-Saharan Africa. Highly adverse temperatures would rather have to be faced by improved heat tolerant cultivars, while strongly adverse decreases in precipitation would have to be faced by expanding irrigation where feasible. While the evaluation of changes in agro-environmental variables like soil organic carbon, erosion, and soil humidity hints that these are major factors influencing climate change resilience of the field crop, no direct relationship between these factors, crop yields

Rising cyclin-CDK levels order cell cycle events.

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Catherine Oikonomou

Full Text Available Diverse mitotic events can be triggered in the correct order and time by a single cyclin-CDK. A single regulator could confer order and timing on multiple events if later events require higher cyclin-CDK than earlier events, so that gradually rising cyclin-CDK levels can sequentially trigger responsive events: the "quantitative model" of ordering.This 'quantitative model' makes predictions for the effect of locking cyclin at fixed levels for a protracted period: at low cyclin levels, early events should occur rapidly, while late events should be slow, defective, or highly variable (depending on threshold mechanism. We titrated the budding yeast mitotic cyclin Clb2 within its endogenous expression range to a stable, fixed level and measured time to occurrence of three mitotic events: growth depolarization, spindle formation, and spindle elongation, as a function of fixed Clb2 level. These events require increasingly more Clb2 according to their normal order of occurrence. Events occur efficiently and with low variability at fixed Clb2 levels similar to those observed when the events normally occur. A second prediction of the model is that increasing the rate of cyclin accumulation should globally advance timing of all events. Moderate (<2-fold overexpression of Clb2 accelerates all events of mitosis, resulting in consistently rapid sequential cell cycles. However, this moderate overexpression also causes a significant frequency of premature mitoses leading to inviability, suggesting that Clb2 expression level is optimized to balance the fitness costs of variability and catastrophe.We conclude that mitotic events are regulated by discrete cyclin-CDK thresholds. These thresholds are sequentially triggered as cyclin increases, yielding reliable order and timing. In many biological processes a graded input must be translated into discrete outputs. In such systems, expression of the central regulator is likely to be tuned to an optimum level, as we

Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomised controlled trial.

Science.gov (United States)

Vora, Ajay; Goulden, Nick; Wade, Rachel; Mitchell, Chris; Hancock, Jeremy; Hough, Rachael; Rowntree, Clare; Richards, Sue

2013-03-01

registered, number ISRCTN07355119. Of 3207 patients registered in the trial overall, 521 MRD low-risk patients were randomly assigned to receive one (n=260) or two (n=261) delayed intensification courses. Median follow-up of these patients was 57 months (IQR 42-72). We recorded no significant difference in EFS between the group given one delayed intensification (94·4% at 5 years, 95% CI 91·1-97·7) and that given two delayed intensifications (95·5%, 92·8-98·2; unadjusted odds ratio 1·00, 95% CI 0·43-2·31; two-sided p=0·99). The difference in 5-year EFS between the two groups was 1·1% (95% CI -5·6 to 2·5). 11 patients (actuarial relapse at 5 years 5·6%, 95% CI 2·3-8·9) given one delayed intensification and six (2·4%, 0·2-4·6) given two delayed intensifications relapsed (p=0·23). Three patients (1·2%, 0-2·6) given two delayed intensifications died of treatment-related causes compared with none in the group given one delayed intensification (p=0·08). We recorded no significant difference between groups for serious adverse events and grade 3 or 4 toxic effects; however, the second delayed intensification course was associated with one (young adults with ALL who are predicted to have a low risk of relapse on the basis of rapid clearance of MRD by the end of induction therapy. Medical Research Council and Leukaemia and Lymphoma Research. Copyright © 2013 Elsevier Ltd. All rights reserved.

Rapid L2 Word Learning through High Constraint Sentence Context: An Event-Related Potential Study

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Baoguo Chen

2017-12-01

Full Text Available Previous studies have found quantity of exposure, i.e., frequency of exposure (Horst et al., 1998; Webb, 2008; Pellicer-Sánchez and Schmitt, 2010, is important for second language (L2 contextual word learning. Besides this factor, context constraint and L2 proficiency level have also been found to affect contextual word learning (Pulido, 2003; Tekmen and Daloglu, 2006; Elgort et al., 2015; Ma et al., 2015. In the present study, we adopted the event-related potential (ERP technique and chose high constraint sentences as reading materials to further explore the effects of quantity of exposure and proficiency on L2 contextual word learning. Participants were Chinese learners of English with different English proficiency levels. For each novel word, there were four high constraint sentences with the critical word at the end of the sentence. Learners read sentences and made semantic relatedness judgment afterwards, with ERPs recorded. Results showed that in the high constraint condition where each pseudoword was embedded in four sentences with consistent meaning, N400 amplitude upon this pseudoword decreased significantly as learners read the first two sentences. High proficiency learners responded faster in the semantic relatedness judgment task. These results suggest that in high quality sentence contexts, L2 learners could rapidly acquire word meaning without multiple exposures, and L2 proficiency facilitated this learning process.

Securing Major Events

International Nuclear Information System (INIS)

Loeoef, Susanna

2013-01-01

When asked why the IAEA should provide nuclear security support to countries that organize large public events, Nuclear Security Officer Sophia Miaw answers quickly and without hesitation. ''Imagine any major public event such as the Olympics, a football championship, or an Expo. If a dirty bomb were to be exploded at a site where tens of thousands of people congregate, the radioactive contamination would worsen the effects of the bomb, increase the number of casualties, impede a rapid emergency response, and cause long term disruption in the vicinity,'' she said. Avoiding such nightmarish scenarios is the driving purpose behind the assistance the IAEA offers States that host major sporting or other public events. The support can range from a single training course to a comprehensive programme that includes threat assessment, training, loaned equipment and exercises. The type and scope of assistance depends on the host country's needs. ''We incorporate nuclear security measures into their security plan. We don't create anything new,'' Miaw said

Contribution of insect pollinators to crop yield and quality varies with agricultural intensification

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Ignasi Bartomeus

2014-03-01

Full Text Available Background. Up to 75% of crop species benefit at least to some degree from animal pollination for fruit or seed set and yield. However, basic information on the level of pollinator dependence and pollinator contribution to yield is lacking for many crops. Even less is known about how insect pollination affects crop quality. Given that habitat loss and agricultural intensification are known to decrease pollinator richness and abundance, there is a need to assess the consequences for different components of crop production.Methods. We used pollination exclusion on flowers or inflorescences on a whole plant basis to assess the contribution of insect pollination to crop yield and quality in four flowering crops (spring oilseed rape, field bean, strawberry, and buckwheat located in four regions of Europe. For each crop, we recorded abundance and species richness of flower visiting insects in ten fields located along a gradient from simple to heterogeneous landscapes.Results. Insect pollination enhanced average crop yield between 18 and 71% depending on the crop. Yield quality was also enhanced in most crops. For instance, oilseed rape had higher oil and lower chlorophyll contents when adequately pollinated, the proportion of empty seeds decreased in buckwheat, and strawberries’ commercial grade improved; however, we did not find higher nitrogen content in open pollinated field beans. Complex landscapes had a higher overall species richness of wild pollinators across crops, but visitation rates were only higher in complex landscapes for some crops. On the contrary, the overall yield was consistently enhanced by higher visitation rates, but not by higher pollinator richness.Discussion. For the four crops in this study, there is clear benefit delivered by pollinators on yield quantity and/or quality, but it is not maximized under current agricultural intensification. Honeybees, the most abundant pollinator, might partially compensate the loss of wild

Contribution of insect pollinators to crop yield and quality varies with agricultural intensification.

Science.gov (United States)

Bartomeus, Ignasi; Potts, Simon G; Steffan-Dewenter, Ingolf; Vaissière, Bernard E; Woyciechowski, Michal; Krewenka, Kristin M; Tscheulin, Thomas; Roberts, Stuart P M; Szentgyörgyi, Hajnalka; Westphal, Catrin; Bommarco, Riccardo

2014-01-01

Background. Up to 75% of crop species benefit at least to some degree from animal pollination for fruit or seed set and yield. However, basic information on the level of pollinator dependence and pollinator contribution to yield is lacking for many crops. Even less is known about how insect pollination affects crop quality. Given that habitat loss and agricultural intensification are known to decrease pollinator richness and abundance, there is a need to assess the consequences for different components of crop production. Methods. We used pollination exclusion on flowers or inflorescences on a whole plant basis to assess the contribution of insect pollination to crop yield and quality in four flowering crops (spring oilseed rape, field bean, strawberry, and buckwheat) located in four regions of Europe. For each crop, we recorded abundance and species richness of flower visiting insects in ten fields located along a gradient from simple to heterogeneous landscapes. Results. Insect pollination enhanced average crop yield between 18 and 71% depending on the crop. Yield quality was also enhanced in most crops. For instance, oilseed rape had higher oil and lower chlorophyll contents when adequately pollinated, the proportion of empty seeds decreased in buckwheat, and strawberries' commercial grade improved; however, we did not find higher nitrogen content in open pollinated field beans. Complex landscapes had a higher overall species richness of wild pollinators across crops, but visitation rates were only higher in complex landscapes for some crops. On the contrary, the overall yield was consistently enhanced by higher visitation rates, but not by higher pollinator richness. Discussion. For the four crops in this study, there is clear benefit delivered by pollinators on yield quantity and/or quality, but it is not maximized under current agricultural intensification. Honeybees, the most abundant pollinator, might partially compensate the loss of wild pollinators in

Intensification agricole en région sahélo-soudanienne. 1. Itinéraires techniques dans un contexte à risques

Directory of Open Access Journals (Sweden)

Abdoulaye Dieng

1997-01-01

Full Text Available Intensification of farming in the Sahelian-Sudanese region. 1. Crop management sequence in a risk context.An experimentation carried out in a station during five consecutive years compared the traditional farming system of the Senegalese groundnut basin to two modernized systems, based on a close synergy between agriculture and livestock productions: a system intensified by draught cultivation (oxen and a system using heavy motorization. The experimentation, implemented at a real farm scale, has taken place in pedo-climatic conditions representative of the region. By producing manure and an important work force, livestock strongly contributes to the success of farming activities. Results show that the suggested intensification models have a beneficial effect on the soil fertility. Several technical options are put forward aiming at a reduction of the risks linked to climatic hazards. Among the main adjustments considered in the modernized systems, we can mention: crop diversification, rotation between cereals and short duration crops ("bissap", black-eyed cowpeas, planned minerai fertilizer application and judicious selection of growing season and soil tilling procedures. Results provide interesting technical references for setting up development programs

Cover crops support ecological intensification of arable cropping systems

Science.gov (United States)

Wittwer, Raphaël A.; Dorn, Brigitte; Jossi, Werner; van der Heijden, Marcel G. A.

2017-02-01

A major challenge for agriculture is to enhance productivity with minimum impact on the environment. Several studies indicate that cover crops could replace anthropogenic inputs and enhance crop productivity. However, so far, it is unclear if cover crop effects vary between different cropping systems, and direct comparisons among major arable production systems are rare. Here we compared the short-term effects of various cover crops on crop yield, nitrogen uptake, and weed infestation in four arable production systems (conventional cropping with intensive tillage and no-tillage; organic cropping with intensive tillage and reduced tillage). We hypothesized that cover cropping effects increase with decreasing management intensity. Our study demonstrated that cover crop effects on crop yield were highest in the organic system with reduced tillage (+24%), intermediate in the organic system with tillage (+13%) and in the conventional system with no tillage (+8%) and lowest in the conventional system with tillage (+2%). Our results indicate that cover crops are essential to maintaining a certain yield level when soil tillage intensity is reduced (e.g. under conservation agriculture), or when production is converted to organic agriculture. Thus, the inclusion of cover crops provides additional opportunities to increase the yield of lower intensity production systems and contribute to ecological intensification.

Intensification Behavior of Mercury Ions on Gold Cyanide Leaching

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Qiang Zhong

2018-01-01

Full Text Available Cyanidation is the main method used to extract gold from gold raw materials; however, a serious problem with this method is the low leaching rate. In order to improve gold leaching, the intensification behavior of mercury ions on gold cyanide leaching, for two types of materials, sulphide gold concentrate and oxide gold ore, was investigated. The results showed that mercury ions, with only a 10−5 M dosage, could significantly intensify leaching and gold recovery. The dissolution behavior of gold plate was also intensified by 10−5 M mercury ions. Microstructure analysis showed that mercury ions intensified the cyanidation corrosion of the gold surface, resulting in a loose structure, where a large number of deep ravines and raised particles were evident across the whole gold surface. The loose structure added contact surface between the gold and cyanide, and accelerated gold dissolution. Moreover, mercury ions obstructed the formation of insoluble products, such as AuCN, Au(OHCN, and Au(OHx, that lead to a passivation membrane on the gold surface, reducing contact between the gold and cyanide. These effects, brought about by mercury ions, change the structure and product of the gold surface during gold cyanidation and promote gold leaching.

RapidIO as a multi-purpose interconnect

Science.gov (United States)

Baymani, Simaolhoda; Alexopoulos, Konstantinos; Valat, Sébastien

2017-10-01

RapidIO (http://rapidio.org/) technology is a packet-switched high-performance fabric, which has been under active development since 1997. Originally meant to be a front side bus, it developed into a system level interconnect which is today used in all 4G/LTE base stations world wide. RapidIO is often used in embedded systems that require high reliability, low latency and scalability in a heterogeneous environment - features that are highly interesting for several use cases, such as data analytics and data acquisition (DAQ) networks. We will present the results of evaluating RapidIO in a data analytics environment, from setup to benchmark. Specifically, we will share the experience of running ROOT and Hadoop on top of RapidIO. To demonstrate the multi-purpose characteristics of RapidIO, we will also present the results of investigating RapidIO as a technology for high-speed DAQ networks using a generic multi-protocol event-building emulation tool. In addition we will present lessons learned from implementing native ports of CERN applications to RapidIO.

Particle production in very-high-energy cosmic-ray emulsion chamber events: Usual and unusual events

International Nuclear Information System (INIS)

Costa, C.G.S.; Halzen, F.; Salles, C.

1995-01-01

We show that a simple scaling model of very forward particle production, consistent with accelerator and air shower data, can describe the overall features of the very-high-energy interactions recorded with emulsion chambers. The rapidity and transverse momentum distribution of the secondaries are quantitatively reproduced. This is somewhat surprising after numerous claims that the same data implied large scaling violations or new dynamics. Interestingly, we cannot describe some of the Centauro events, suggesting that these events are anomalous independently of their well-advertised unusual features such as the absence of neutral secondaries

Intensification of the process of sorption of copper ions by yeast of Saccharomyces cerevisiae 1968 by means of a permanent magnetic field

International Nuclear Information System (INIS)

Gorobets, Svetlana; Gorobets, Oksana; Ukrainetz, Anatoliy; Kasatkina, Taisiya; Goyko, Irina

2004-01-01

Possibility to replace mechanical stirring by magnetic field-induced one was shown for intensification of yeast biosorption and cementation. Combined method of metal ion recover, including Cu ion sorption by yeast Saccharomyces cerevisiae and Cu cementation on a surface of a steel matrix, is tested in a case of magnetic field-induced stirring

Evaluating different approaches to non-destructive nitrogen status diagnosis of rice using portable RapidSCAN active canopy sensor.

Science.gov (United States)

Lu, Junjun; Miao, Yuxin; Shi, Wei; Li, Jingxin; Yuan, Fei

2017-10-26

RapidSCAN is a new portable active crop canopy sensor with three wavebands in red, red-edge, and near infrared spectral regions. The objective of this study was to determine the potential and practical approaches of using this sensor for non-destructive diagnosis of rice nitrogen (N) status. Sixteen plot experiments and ten on-farm experiments were conducted from 2014 to 2016 in Jiansanjiang Experiment Station of the China Agricultural University and Qixing Farm in Northeast China. Two mechanistic and three semi-empirical approaches using the sensor's default vegetation indices, normalized difference vegetation index and normalized difference red edge, were evaluated in comparison with the top performing vegetation indices selected from 51 tested indices. The results indicated that the most practical and stable method of using the RapidSCAN sensor for rice N status diagnosis is to calculate N sufficiency index with the default vegetation indices and then to estimate N nutrition index non-destructively (R 2  = 0.50-0.59). This semi-empirical approach achieved a diagnosis accuracy rate of 59-76%. The findings of this study will facilitate the application of the RapidSCAN active sensor for rice N status diagnosis across growth stages, cultivars and site-years, and thus contributing to precision N management for sustainable intensification of agriculture.

Pathways linking drug use and labour market trajectories: the role of catastrophic events.

Science.gov (United States)

Richardson, Lindsey; Small, Will; Kerr, Thomas

2016-01-01

People affected by substance use disorders often experience sub-optimal employment outcomes. The role of drug use in processes that produce and entrench labour market precarity among people who inject drugs (PWID) have not, however, been fully described. We recruited 22 PWID from ongoing prospective cohort studies in Vancouver, Canada, with whom we conducted semi-structured retrospective interviews and then employed a thematic analysis that drew on concepts from life course theory to explore the mechanisms and pathways linking drug use and labour market trajectories. The participants' narratives identified processes corresponding to causation, whereby suboptimal employment outcomes led to harmful drug use; direct selection, where impairment, health complications or drug-seeking activities selected individuals out of employment; and indirect selection, where external factors, such as catastrophic events, marked the initiation or intensification of substance use concurrent with sudden changes in capacities for employment. Catastrophic events linking negative transitions in both drug use and labour market trajectories were of primary importance, demarcating critical initiation and transitional events in individual risk trajectories. These results challenge conventional assumptions about the primacy of drug use in determining employment outcomes among PWID and suggest the importance of multidimensional support to mitigate the initiation, accumulation and entrenchment of labour market and drug-related disadvantage. © 2015 Foundation for the Sociology of Health & Illness.

Predicting the Trends of Social Events on Chinese Social Media.

Science.gov (United States)

Zhou, Yang; Zhang, Lei; Liu, Xiaoqian; Zhang, Zhen; Bai, Shuotian; Zhu, Tingshao

2017-09-01

Growing interest in social events on social media came along with the rapid development of the Internet. Social events that occur in the "real" world can spread on social media (e.g., Sina Weibo) rapidly, which may trigger severe consequences and thus require the government's timely attention and responses. This article proposes to predict the trends of social events on Sina Weibo, which is currently the most popular social media in China. Based on the theories of social psychology and communication sciences, we extract an unprecedented amount of comprehensive and effective features that relate to the trends of social events on Chinese social media, and we construct the trends of prediction models by using three classical regression algorithms. We found that lasso regression performed better with the precision 0.78 and the recall 0.88. The results of our experiments demonstrated the effectiveness of our proposed approach.

Watershed responses to Amazon soya bean cropland expansion and intensification.

Science.gov (United States)

Neill, Christopher; Coe, Michael T; Riskin, Shelby H; Krusche, Alex V; Elsenbeer, Helmut; Macedo, Marcia N; McHorney, Richard; Lefebvre, Paul; Davidson, Eric A; Scheffler, Raphael; Figueira, Adelaine Michela e Silva; Porder, Stephen; Deegan, Linda A

2013-06-05

The expansion and intensification of soya bean agriculture in southeastern Amazonia can alter watershed hydrology and biogeochemistry by changing the land cover, water balance and nutrient inputs. Several new insights on the responses of watershed hydrology and biogeochemistry to deforestation in Mato Grosso have emerged from recent intensive field campaigns in this region. Because of reduced evapotranspiration, total water export increases threefold to fourfold in soya bean watersheds compared with forest. However, the deep and highly permeable soils on the broad plateaus on which much of the soya bean cultivation has expanded buffer small soya bean watersheds against increased stormflows. Concentrations of nitrate and phosphate do not differ between forest or soya bean watersheds because fixation of phosphorus fertilizer by iron and aluminium oxides and anion exchange of nitrate in deep soils restrict nutrient movement. Despite resistance to biogeochemical change, streams in soya bean watersheds have higher temperatures caused by impoundments and reduction of bordering riparian forest. In larger rivers, increased water flow, current velocities and sediment flux following deforestation can reshape stream morphology, suggesting that cumulative impacts of deforestation in small watersheds will occur at larger scales.

Rapidly Evolving Transients in the Dark Energy Survey

Energy Technology Data Exchange (ETDEWEB)

Pursiainen, M.; et al.

2018-03-13

We present the results of a search for rapidly evolving transients in the Dark Energy Survey Supernova Programme. These events are characterized by fast light curve evolution (rise to peak in $\\lesssim 10$ d and exponential decline in $\\lesssim30$ d after peak). We discovered 72 events, including 37 transients with a spectroscopic redshift from host galaxy spectral features. The 37 events increase the total number of rapid optical transients by more than factor of two. They are found at a wide range of redshifts ($0.05M_\\mathrm{g}>-22.25$). The multiband photometry is well fit by a blackbody up to few weeks after peak. The events appear to be hot ($T\\approx10000-30000$ K) and large ($R\\approx 10^{14}-2\\cdot10^{15}$ cm) at peak, and generally expand and cool in time, though some events show evidence for a receding photosphere with roughly constant temperature. Spectra taken around peak are dominated by a blue featureless continuum consistent with hot, optically thick ejecta. We compare our events with a previously suggested physical scenario involving shock breakout in an optically thick wind surrounding a core-collapse supernova (CCSNe), we conclude that current models for such a scenario might need an additional power source to describe the exponential decline. We find these transients tend to favor star-forming host galaxies, which could be consistent with a core-collapse origin. However, more detailed modeling of the light curves is necessary to determine their physical origin.

Charged particle multiplicity distributions in restricted rapidity intervals in Z0 hadronic decays

International Nuclear Information System (INIS)

Uvarov, V.

1991-01-01

The multiplicity distributions of charged particles in restricted rapidity intervals in Z 0 hadronic decays measured by the DELPHI detector are presented. The data reveal a shoulder structure, best visible for intervals of intermediate size, i.e. for rapidity limits around ±1.5. The whole set of distributions including the shoulder structure is reproduced by the Lund Parton Shower model. The structure is found to be due to important contributions from 3- and 4-jet events with a hard gluon jet. A different model, based on the concept of independently produced groups of particles, 'clans', fluctuating both in number per event and particle content per clan, has also been used to analyse the present data. The results show that for each interval of rapidity the average number of clans per event is approximately the same as at lower energies. (author) 11 refs., 3 figs

Inclusive rapidity correlations of π- mesons in pp interactions

International Nuclear Information System (INIS)

Golokhvastov, A.I.

1994-01-01

The simple single-parameter approximation of one-particle semi-inclusive rapidity distributions of negative particles (π - mesons) in pp interactions at various multiplicities over the investigated range of primary momenta 6.6 -400 GeV/c is presented. Assuming the lack of any kind of correlations in semi-inclusive events, a good description of experimental data on two-particle inclusive rapidity correlations (pseudocorrelations) is obtained. Data on forward-backward, right-left correlations and multiplicity distributions in rapidity intervals and intervals separated by empty gaps do not contradict independent π - production either. (orig.)

JINR rapid communications

International Nuclear Information System (INIS)

1995-01-01

The present collection of rapid communications from JINR, Dubna, contains six separate reports on Monte Carlo simulation of silicon detectors for the ALICE experiment at LHC, a study of single tagged multihadronic γγ* events at an average Q 2 of 90 GeV 2 , epithermal neutron activation analysis of moss, lichen and pine needles in atmospheric deposition monitoring, the theory of neutrino oscillation, coupled quadrupole and monopole vibrations of large amplitude and test of the Ellis-Jaffe sum rule using parametrization of the measured lepton-proton asymmetry. 21 figs., 18 tabs

Looming Scarcity of Phosphate Rock and Intensification of Soil Phosphorus Research

Directory of Open Access Journals (Sweden)

Philippe C. Baveye

2015-06-01

Full Text Available In recent years, many researchers have claimed that world reserves of rock phosphate were getting depleted at an alarming rate, putting us on the path to scarcity of that essential resource within the next few decades. Others have claimed that such alarmist forecasts were frequent in the past and have always been proven unfounded, making it likely that the same will be true in the future. Both viewpoints are directly relevant to the level of funding devoted to research on the use of phosphate fertilizers. In this short essay, it is argued that information about future reserves of P or any other resource are impossible to predict, and therefore that the threat of a possible depletion of P reserves should not be used as a key motivation for an intensification of research on soil P. However, there are other, more compelling reasons, both geopolitical and environmental, to urgently step up our collective efforts to devise agricultural practices that make better use of P than is the case at the moment.

Performance Assessment of a Post-Closure Pyrophoric Event

International Nuclear Information System (INIS)

Duguid, James; Senger, R.; Leem, J.

2001-01-01

The U.S. Department of Energy (DOE) spent nuclear fuel (DSNF) is categorized into eleven different spent fuel groups. Group 7, is predominantly uranium metal spent fuel from N Reactor that could oxidize rapidly in the presence of air when a waste package is breached. Such rapid oxidation constitutes a pyrophoric event. The consequences of a post closure pyrophoric event were evaluated in terms of its potential to damage adjacent waste packages and consequences of it in terms of long-term dose to humans. This work was conducted as part of the total system performance assessment (TSPA) of DOE spent fuel for the National Spent Nuclear Fuel Program. These analyses were performed in support of the site recommendation for a repository at Yucca Mountain, Nevada

Role of upper ocean parameters in the genesis, intensification and tracks of cyclones over the Bay of Bengal

Digital Repository Service at National Institute of Oceanography (India)

Maneesha, K.; Sadhuram, Y.; Prasad, K.V.S.R.

of high heat potential (>90 kj/cm2) in the western Gulf of Mexico (Goni et al. 2003, 2009; Shay et al. 2000). Further, Hurricanes Igor (tropical Atlantic) and Celia (Eastern North Pacific), Typhoon Megi (Western North Pacific) and Cyclone Phet (Arabian Sea... 2009/10 in the Gulf of Mexico and the southwestern Pacific Ocean, while there was an increase in the western Pacific Ocean, Arabian Sea and Bay of Bengal. All the above studies emphasize the importance of the UOHC in the genesis and intensification...

High-Resolution Biogeochemical Simulation Identifies Practical Opportunities for Bioenergy Landscape Intensification Across Diverse US Agricultural Regions

Science.gov (United States)

Field, J.; Adler, P. R.; Evans, S.; Paustian, K.; Marx, E.; Easter, M.

2015-12-01

The sustainability of biofuel expansion is strongly dependent on the environmental footprint of feedstock production, including both direct impacts within feedstock-producing areas and potential leakage effects due to disruption of existing food, feed, or fiber production. Assessing and minimizing these impacts requires novel methods compared to traditional supply chain lifecycle assessment. When properly validated and applied at appropriate spatial resolutions, biogeochemical process models are useful for simulating how the productivity and soil greenhouse gas fluxes of cultivating both conventional crops and advanced feedstock crops respond across gradients of land quality and management intensity. In this work we use the DayCent model to assess the biogeochemical impacts of agricultural residue collection, establishment of perennial grasses on marginal cropland or conservation easements, and intensification of existing cropping at high spatial resolution across several real-world case study landscapes in diverse US agricultural regions. We integrate the resulting estimates of productivity, soil carbon changes, and nitrous oxide emissions with crop production budgets and lifecycle inventories, and perform a basic optimization to generate landscape cost/GHG frontiers and determine the most practical opportunities for low-impact feedstock provisioning. The optimization is constrained to assess the minimum combined impacts of residue collection, land use change, and intensification of existing agriculture necessary for the landscape to supply a commercial-scale biorefinery while maintaining exiting food, feed, and fiber production levels. These techniques can be used to assess how different feedstock provisioning strategies perform on both economic and environmental criteria, and sensitivity of performance to environmental and land use factors. The included figure shows an example feedstock cost-GHG mitigation tradeoff frontier for a commercial-scale cellulosic

Intensificação do trabalho e saúde dos professores Work intensification and teachers' health

Directory of Open Access Journals (Sweden)

Ada Ávila Assunção

2009-08-01

Full Text Available A centralidade atribuída aos docentes nos processos de reformas educacionais em curso traz novas exigências profissionais com efeitos sobre a sua saúde. Buscando resultados na literatura epidemiológica e ergonômica, este artigo tece relações entre o processo de intensificação do trabalho nas escolas e o tipo de adoecimento dos professores descrito nos estudos atuais. Sobre a intensificação, são mencionados fatores qualitativos, caracterizados pelas transformações da atividade sem o necessário suporte social para acomodar as exigências do trabalho, e fatores quantitativos, relacionados ao aumento do volume de tarefas nas escolas. As evidências trazidas ao texto permitem esboçar as bases de um modelo explicativo para o processo de morbidade docente calcado em determinantes ambientais e organizacionais e suas implicações sobre a atividade de trabalho na sala de aula.The centrality given to teachers in the ongoing educational reforms creates new professional demands that affect their health. Seeking results in the literature on epidemiology and ergonomics, this paper suggests relations between the work intensification process in schools and the types of teachers' illnesses described in current studies. With regard to work intensification, mention is made of both qualitative factors, characterized by changes in activities without the necessary social support to accommodate work requirements, and quantitative factors such as increased work loads in schools. Evidence presented in the text allows for a first explanatory model for the teacher morbidity process, based on environmental and organizational determinants, and their implications for classroom work activities.

Rapidity gaps between jets in p bar p collisions at √s =1.8 TeV

International Nuclear Information System (INIS)

Abachi, S.; Abbott, B.; Abolins, M.; Acharya, B.S.; Adam, I.; Adams, D.L.; Adams, M.; Ahn, S.; Aihara, H.; Alvarez, G.; Alves, G.A.; Amos, N.; Anderson, E.W.; Antipov, Y.; Aronson, S.H.; Astur, R.; Avery, R.E.; Baden, A.; Balamurali, V.; Balderston, J.; Baldin, B.; Bantly, J.; Bartlett, J.F.; Bazizi, K.; Behnke, T.; Bendich, J.; Beri, S.B.; Bezzubov, V.; Bhat, P.C.; Bhatnagar, V.; Biswas, N.; Blazey, G.; Blessing, S.; Boehnlein, A.; Borcherding, F.; Borders, J.; Bozko, N.; Brandt, A.; Brock, R.; Bross, A.; Buchholz, D.; Burtovoi, V.; Butler, J.M.; Callot, O.H.; Castilla-Valdez, H.; Chakraborty, D.; Chekulaev, S.; Chen, J.; Chen, L.; Chen, W.; Chevalier, L.; Chopra, S.; Choudhary, B.C.; Christenson, J.H.; Chung, M.; Claes, D.; Clark, A.R.; Cobau, W.G.; Cochran, J.; Cooper, W.E.; Cretsinger, C.; Cullen-Vidal, D.; Cummings, M.; Cussonneau, J.P.; Cutts, D.; Dahl, O.I.; De, K.; Demarteau, M.; Demina, R.; Denisenko, K.; Denisenko, N.; Denisov, D.; Denisov, S.; Dharmaratna, W.; Diehl, H.T.; Diesburg, M.; Dixon, R.; Draper, P.; Ducros, Y.; Durston-Johnson, S.; Eartly, D.; Edmunds, D.; Efimov, A.; Ellison, J.; Elvira, V.D.; Engelmann, R.; Eppley, G.; Eroshin, O.; Evdokimov, V.; Fahey, S.; Fanourakis, G.; Fatyga, M.; Fatyga, M.K.; Featherly, J.; Feher, S.; Fein, D.; Ferbel, T.; Finocchiaro, G.; Fisk, H.E.; Flattum, E.; Forden, G.E.; Fortner, M.; Franzini, P.; Fredriksen, S.; Fuess, S.; Gao, C.S.; Geld, T.L.; Genser, K.; Gerber, C.E.; Gibbard, B.; Glebov, V.; Glicenstein, J.F.; Gobbi, B.; Goforth, M.; Goldschmidt, M.; Gomez, B.; Good, M.L.; Gordon, H.; Graf, N.; Grannis, P.D.; Green, D.R.; Green, J.; Greenlee, H.; Grossman, N.; Grudberg, P.; Gruenendahl, S.; Guida, J.A.; Guida, J.M.; Guryn, W.; Hadley, N.J.; Haggerty, H.; Hagopian, S.; Hagopian, V.; Hall, R.E.; Hansen, S.; Hauptman, J.M.; Hedin, D.; Heinson, A.P.; Heintz, U.; Herrera-Corral, G.; Heuring, T.; Hirosky, R.; Hoeneisen, B.; Hoftun, J.S.; Hu, T.; Hubbard, J.R.; Huehn, T.; Igarashi, S.; Ito, A.S.

1994-01-01

First experimental results are presented from a search for events with a rapidity gap between jets. The D0 detector was used to examine events produced by the Fermilab Tevatron p bar p collider at √s =1.8 TeV. The fraction of events with an observed rapidity gap between the two highest transverse energy (E T ) jets is measured as a function of the pseudorapidity separation between the jet edges (Δη c ). An upper limit at the 95% confidence level of 1.1x10 -2 is obtained on the fraction of events with non particles between the jets, for events with Δη c >3 and jet E T greater than 30 GeV

Entry Level Skills for the Event Management Profession: Implications for Curriculum Development

Science.gov (United States)

Fletcher, Donna; Dunn, Julie; Prince, Rosemary

2009-01-01

The rapid growth of the event industry has resulted in a world-wide demand for education and training programs in event management. While the professional associations in event management have provided providing quality training and credentialing for their members, the 140 colleges and universities preparing students for entry level positions in…

Agricultural innovations for sustainable crop production intensification

Directory of Open Access Journals (Sweden)

Michele Pisante

2012-10-01

Full Text Available Sustainable crop production intensification should be the first strategic objective of innovative agronomic research for the next 40 years. A range of options exist (often very location specific for farming practices, approaches and technologies that ensure sustainability, while at the same time improving crop production. The main challenge is to encourage farmers in the use of appropriate technologies,  and  to  ensure  that  knowledge  about  sound  production  practices  is  increasingly accepted and applied by farmers. There is a huge, but underutilized potential to link farmers’ local knowledge with science-based innovations, through favourable institutional arrangements.  The same  holds  for  the  design,  implementation  and  monitoring  of  improved  natural  resource management  that  links  community  initiatives  to  external  expertise.  It is also suggested that a comprehensive effort be undertaken to measure different stages of the innovation system, including technological adoption and diffusion at the farm level, and to investigate the impact of agricultural policies on technological change and technical efficiency. This paper provides a brief review of agronomic management practices that support sustainable crop production system and evidence on developments  in the selection of crops and cultivars; describes farming systems for crop which take a predominantly ecosystem approach; discusses the scientific application of ecosystem principles for the management of pest and weed populations; reviews the  improvements in fertilizer and nutrient management that explain productivity growth; describes the benefits and constraints of irrigation technologies; and suggests a way forward. Seven changes in the context for agricultural development are proposed that heighten the need to examine how innovation occurs in the agricultural sector.

Reconciling Biodiversity Conservation and Timber Production in Mixed Uneven-Aged Mountain Forests: Identification of Ecological Intensification Pathways.

Science.gov (United States)

Lafond, Valentine; Cordonnier, Thomas; Courbaud, Benoît

2015-11-01

Mixed uneven-aged forests are considered favorable to the provision of multiple ecosystem services and to the conciliation of timber production and biodiversity conservation. However, some forest managers now plan to increase the intensity of thinning and harvesting operations in these forests. Retention measures or gap creation are considered to compensate potential negative impacts on biodiversity. Our objectives were to assess the effect of these management practices on timber production and biodiversity conservation and identify potential compensating effects between these practices, using the concept of ecological intensification as a framework. We performed a simulation study coupling Samsara2, a simulation model designed for spruce-fir uneven-aged mountain forests, an uneven-aged silviculture algorithm, and biodiversity models. We analyzed the effect of parameters related to uneven-aged management practices on timber production, biodiversity, and sustainability indicators. Our study confirmed that the indicators responded differently to management practices, leading to trade-offs situations. Increasing management intensity had negative impacts on several biodiversity indicators, which could be partly compensated by the positive effect of retention measures targeting large trees, non-dominant species, and deadwood. The impact of gap creation was more mitigated, with a positive effect on the diversity of tree sizes and deadwood but a negative impact on the spruce-fir mixing balance and on the diversity of the understory layer. Through the analysis of compensating effects, we finally revealed the existence of possible ecological intensification pathways, i.e., the possibility to increase management intensity while maintaining biodiversity through the promotion of nature-based management principles (gap creation and retention measures).

Rapid shelf-wide cooling response of a stratified coastal ocean to hurricanes.

Science.gov (United States)

Seroka, Greg; Miles, Travis; Xu, Yi; Kohut, Josh; Schofield, Oscar; Glenn, Scott

2017-06-01

Large uncertainty in the predicted intensity of tropical cyclones (TCs) persists compared to the steadily improving skill in the predicted TC tracks. This intensity uncertainty has its most significant implications in the coastal zone, where TC impacts to populated shorelines are greatest. Recent studies have demonstrated that rapid ahead-of-eye-center cooling of a stratified coastal ocean can have a significant impact on hurricane intensity forecasts. Using observation-validated, high-resolution ocean modeling, the stratified coastal ocean cooling processes observed in two U.S. Mid-Atlantic hurricanes were investigated: Hurricane Irene (2011)-with an inshore Mid-Atlantic Bight (MAB) track during the late summer stratified coastal ocean season-and Tropical Storm Barry (2007)-with an offshore track during early summer. For both storms, the critical ahead-of-eye-center depth-averaged force balance across the entire MAB shelf included an onshore wind stress balanced by an offshore pressure gradient. This resulted in onshore surface currents opposing offshore bottom currents that enhanced surface to bottom current shear and turbulent mixing across the thermocline, resulting in the rapid cooling of the surface layer ahead-of-eye-center. Because the same baroclinic and mixing processes occurred for two storms on opposite ends of the track and seasonal stratification envelope, the response appears robust. It will be critical to forecast these processes and their implications for a wide range of future storms using realistic 3-D coupled atmosphere-ocean models to lower the uncertainty in predictions of TC intensities and impacts and enable coastal populations to better respond to increasing rapid intensification threats in an era of rising sea levels.

Rapid shelf‐wide cooling response of a stratified coastal ocean to hurricanes

Science.gov (United States)

Miles, Travis; Xu, Yi; Kohut, Josh; Schofield, Oscar; Glenn, Scott

2017-01-01

Abstract Large uncertainty in the predicted intensity of tropical cyclones (TCs) persists compared to the steadily improving skill in the predicted TC tracks. This intensity uncertainty has its most significant implications in the coastal zone, where TC impacts to populated shorelines are greatest. Recent studies have demonstrated that rapid ahead‐of‐eye‐center cooling of a stratified coastal ocean can have a significant impact on hurricane intensity forecasts. Using observation‐validated, high‐resolution ocean modeling, the stratified coastal ocean cooling processes observed in two U.S. Mid‐Atlantic hurricanes were investigated: Hurricane Irene (2011)—with an inshore Mid‐Atlantic Bight (MAB) track during the late summer stratified coastal ocean season—and Tropical Storm Barry (2007)—with an offshore track during early summer. For both storms, the critical ahead‐of‐eye‐center depth‐averaged force balance across the entire MAB shelf included an onshore wind stress balanced by an offshore pressure gradient. This resulted in onshore surface currents opposing offshore bottom currents that enhanced surface to bottom current shear and turbulent mixing across the thermocline, resulting in the rapid cooling of the surface layer ahead‐of‐eye‐center. Because the same baroclinic and mixing processes occurred for two storms on opposite ends of the track and seasonal stratification envelope, the response appears robust. It will be critical to forecast these processes and their implications for a wide range of future storms using realistic 3‐D coupled atmosphere‐ocean models to lower the uncertainty in predictions of TC intensities and impacts and enable coastal populations to better respond to increasing rapid intensification threats in an era of rising sea levels. PMID:28944132

Observation of rapidity gaps in bar pp collisions at 1.8 TeV

International Nuclear Information System (INIS)

Abe, F.; Albrow, M.; Amidei, D.; Anway-Wiese, C.; Apollinari, G.; Atac, M.; Auchincloss, P.; Azzi, P.; Bacchetta, N.; Baden, A.R.; Badgett, W.; Bailey, M.W.; Bamberger, A.; de Barbaro, P.; Barbaro-Galtieri, A.; Barnes, V.E.; Barnett, B.A.; Bartalini, P.; Bauer, G.; Baumann, T.; Bedeschi, F.; Behrends, S.; Belforte, S.; Bellettini, G.; Bellinger, J.; Benjamin, D.; Benlloch, J.; Bensinger, J.; Beretvas, A.; Berge, J.P.; Bertolucci, S.; Biery, K.; Bhadra, S.; Binkley, M.; Bisello, D.; Blair, R.; Blocker, C.; Bodek, A.; Bolognesi, V.; Booth, A.W.; Boswell, C.; Brandenburg, G.; Brown, D.; Buckley-Geer, E.; Budd, H.S.; Busetto, G.; Byon-Wagner, A.; Byrum, K.L.; Campagnari, C.; Campbell, M.; Caner, A.; Carey, R.; Carithers, W.; Carlsmith, D.; Carroll, J.T.; Cashmore, R.; Castro, A.; Cen, Y.; Cervelli, F.; Chadwick, K.; Chapman, J.; Chiarelli, G.; Chinowsky, W.; Cihangir, S.; Clark, A.G.; Cobal, M.; Connor, D.; Contreras, M.; Cooper, J.; Cordelli, M.; Crane, D.; Cunningham, J.D.; Day, C.; DeJongh, F.; Dell'Agnello, S.; Dell'Orso, M.; Demortier, L.; Denby, B.; Derwent, P.F.; Devlin, T.; Dickson, M.; Donati, S.; Drucker, R.B.; Dunn, A.; Einsweiler, K.; Elias, J.E.; Ely, R.; Eno, S.; Errede, S.; Etchegoyen, A.; Farhat, B.; Feldman, G.J.; Flaugher, B.; Foster, G.W.; Franklin, M.; Frautschi, M.; Freeman, J.; Frisch, H.; Fuess, T.; Fukui, Y.; Gagliardi, G.; Garfinkel, A.F.; Gauthier, A.; Geer, S.; Gerdes, D.W.; Giannetti, P.; Giokaris, N.; Gladney, L.; Gold, M.; Gonzalez, J.; Goshaw, A.; Goulianos, K.; Grassmann, H.; Grieco, G.M.; Grindley, R.; Grosso-Pilcher, C.; Haber, C.; Hahn, S.R.; Handler, R.; Hara, K.; Harral, B.; Harris, R.M.; Hauger, S.A.; Hauser, J.; Hawk, C.; Hessing, T.; Hollebeek, R.; Holloway, L.; Hoelscher, A.; Hong, S.; Houk, G.; Hu, P.; Hubbard, B.; Huffman, B.T.; Hughes, R.; Hurst, P.; Huth, J.; Hylen, J.; Incagli, M.; Ino, T.; Iso, H.; Jensen, H.; Jessop, C.P.; Johnson, R.P.; Joshi, U.; Kadel, R.W.; Kamon, T.; Kanda, S.; Kardelis, D.A.; Karliner, I.

1995-01-01

In pp bar pp collisions at √s=1.8TeV we find jet events with a rapidity gap topology. The number of hadrons in the rapidity interval Δη D between leading-jet cones was sampled by charged tracks with P T >400MeV/c. We find excess trackless events beyond that expected in a smooth multiplicity distribution. In a control region outside Δη D we see no excess. For Δη D >0.8, the fraction of excess trackless events, consistent with estimates based on exchange of color-singlet digluons, is R(gap)=σ jet (gap)/σ jet = 0.0085±0.0012(stat) -0.0012 +0.0024 (syst)

Abnormal occipital event-related potentials in Parkinson's disease with concomitant REM sleep behavior disorder.

Science.gov (United States)

Gaudreault, Pierre-Olivier; Gagnon, Jean-François; Montplaisir, Jacques; Vendette, Mélanie; Postuma, Ronald B; Gagnon, Katia; Gosselin, Nadia

2013-02-01

Rapid eye movement sleep behavior disorder is found in 33-46% of patients with Parkinson's disease and was shown to be associated with cognitive deficits. Our goal was to improve our understanding of the role of this sleep disorder in cerebral dysfunction occurring in Parkinson's disease using a visual cognitive task and event-related potentials. Sixteen patients with Parkinson's disease and rapid eye movement sleep behavior disorder, 15 patients with Parkinson's disease without rapid eye movement sleep behavior disorder and 16 healthy control subjects were included. The amplitude and latency of event-related potentials were compared between groups. No group differences were found for reaction times or accuracy. A Group effect was found for P2 wave amplitude; patients with rapid eye movement sleep behavior disorder had increased P2 in comparison with the control group (p disorder were associated with abnormal visual P2 component of event-related potentials. Although patients with Parkinson's disease alone were not significantly different from patients with combined Parkinson's disease and rapid eye movement sleep behavior disorder, their P2 amplitudes were not sufficiently abnormal to differ from that of control subjects. This study confirms that rapid eye movement sleep behavior disorder accentuates cerebral dysfunctions in Parkinson's disease. Copyright © 2012 Elsevier Ltd. All rights reserved.

Anticipating demand for emergency health services due to medication-related adverse events after rapid mass prophylaxis campaigns.

Science.gov (United States)

Hupert, Nathaniel; Wattson, Daniel; Cuomo, Jason; Benson, Samuel

2007-03-01

Mass prophylaxis against infectious disease outbreaks carries the risk of medication-related adverse events (MRAEs). The authors sought to define the relationship between the rapidity of mass prophylaxis dispensing and the subsequent demand for emergency health services due to predictable MRAEs. The authors created a spreadsheet-based computer model that calculates scenario-specific predicted daily MRAE rates from user inputs by applying a probability distribution to the reported timing of MRAEs. A hypothetical two- to ten-day prophylaxis campaign for one million people using recent data from both smallpox vaccination and anthrax chemoprophylaxis campaigns was modeled. The length of a mass prophylaxis campaign plays an important role in determining the subsequent intensity in emergency services utilization due to real or suspected adverse events. A two-day smallpox vaccination scenario would produce an estimated 32,000 medical encounters and 1,960 hospitalizations, peaking at 5,246 health care encounters six days after the start of the campaign; in contrast, a ten-day campaign would lead to 41% lower peak surge, with a maximum of 3,106 encounters on the busiest day, ten days after initiation of the campaign. MRAEs with longer lead times, such as those associated with anthrax chemoprophylaxis, exhibit less variability based on campaign length (e.g., 124 out of an estimated 1,400 hospitalizations on day 20 after a two-day campaign versus 103 on day 24 after a ten-day campaign). The duration of a mass prophylaxis campaign may have a substantial impact on the timing and peak number of clinically significant MRAEs, with very short campaigns overwhelming existing emergency department (ED) capacity to treat real or suspected medication-related injuries. While better reporting of both incidence and timing of MRAEs in future prophylaxis campaigns should improve the application of this model to community-based emergency preparedness planning, these results highlight the need

An Event Related Field Study of Rapid Grammatical Plasticity in Adult Second-Language Learners

Science.gov (United States)

Bastarrika, Ainhoa; Davidson, Douglas J.

2017-01-01

The present study used magnetoencephalography (MEG) to investigate how Spanish adult learners of Basque respond to morphosyntactic violations after a short period of training on a small fragment of Basque grammar. Participants (n = 17) were exposed to violation and control phrases in three phases (pretest, training, generalization-test). In each phase participants listened to short Basque phrases and they judged whether they were correct or incorrect. During the pre-test and generalization-test, participants did not receive any feedback. During the training blocks feedback was provided after each response. We also ran two Spanish control blocks before and after training. We analyzed the event-related magnetic- field (ERF) recorded in response to a critical word during all three phases. In the pretest, classification was below chance and we found no electrophysiological differences between violation and control stimuli. Then participants were explicitly taught a Basque grammar rule. From the first training block participants were able to correctly classify control and violation stimuli and an evoked violation response was present. Although the timing of the electrophysiological responses matched participants' L1 effect, the effect size was smaller for L2 and the topographical distribution differed from the L1. While the L1 effect was bilaterally distributed on the auditory sensors, the L2 effect was present at right frontal sensors. During training blocks two and three, the violation-control effect size increased and the topography evolved to a more L1-like pattern. Moreover, this pattern was maintained in the generalization test. We conclude that rapid changes in neuronal responses can be observed in adult learners of a simple morphosyntactic rule, and that native-like responses can be achieved at least in small fragments of second language. PMID:28174530

Late Holocene environmental reconstructions and their implications on flood events, typhoon, and agricultural activities in NE Taiwan

Science.gov (United States)

Wang, L.-C.; Behling, H.; Lee, T.-Q.; Li, H.-C.; Huh, C.-A.; Shiau, L.-J.; Chang, Y.-P.

2014-10-01

We reconstructed paleoenvironmental changes from a sediment archive of a lake in the floodplain of the Ilan Plain of NE Taiwan on multi-decadal resolution for the last ca. 1900 years. On the basis of pollen and diatom records, we evaluated past floods, typhoons, and agricultural activities in this area which are sensitive to the hydrological conditions in the western Pacific. Considering the high sedimentation rates with low microfossil preservations in our sedimentary record, multiple flood events were. identified during the period AD 100-1400. During the Little Ice Age phase 1 (LIA 1 - AD 1400-1620), the abundant occurrences of wetland plant (Cyperaceae) and diatom frustules imply less flood events under stable climate conditions in this period. Between AD 500 and 700 and the Little Ice Age phase 2 (LIA 2 - AD 1630-1850), the frequent typhoons were inferred by coarse sediments and planktonic diatoms, which represented more dynamical climate conditions than in the LIA 1. By comparing our results with the reconstructed changes in tropical hydrological conditions, we suggested that the local hydrology in NE Taiwan is strongly influenced by typhoon-triggered heavy rainfalls, which could be influenced by the variation of global temperature, the expansion of the Pacific warm pool, and the intensification of El Niño-Southern Oscillation (ENSO) events.

Utilizing web-based geodata for rapid disaster identification and assessment

Science.gov (United States)

Leith, Kerry; Schmitt, Michael; Sickert, Salomon; Metzger, Alex; Krautblatter, Michael

2014-05-01

Developing methods to rapidly locate and quantify the impact of natural disasters can aid both the coordination of emergency response, and the long-term understanding of natural hazards in a range of environmental settings. Gaining such quantitative data in the aftermath of landslide events is particularly challenging, as the localized nature, steep terrain, and frequent damage to infrastructure caused by common triggering events (e.g. earthquakes, storms) complicates traditional methods of survey and data communication. As a result, the first, and often best overview of disastrous events is typically provided by eyewitness or first-responder photographs distributed through official, or social media networks. Although these images allow for an initial qualitative assessment of the event, their ad-hoc nature does not currently allow for either precise location, or quantitative evaluation of key event parameters (e.g. structural setting, geology, geometry, size, transport path, or total fall height). Here we present two tools designed to facilitate initial location and assessment of key event parameters using a combination of freely available geodata and information derived from eyewitness observations. These tools are currently under development, and rely on the adaptation of existing photogrammetric techniques in order to allow users to rapidly map and quantify event parameters from a combination of ad-hoc media photographs, and existing orthophoto and digital terrain model data (e.g. LiDAR, SRTM, ASTER). By incorporating results in freely-available GIS platforms such as Google Earth, local authorities will be able to to better assess and disseminate information regarding the impact of natural disasters in the critical hours following an event. We expect that quantitative data derived from events will provide important information to allow geohazard researchers to better assess landslide generation, and authorities to better plan responses to future triggering

Applying Lean principles and Kaizen rapid improvement events in public health practice.

Science.gov (United States)

Smith, Gene; Poteat-Godwin, Annah; Harrison, Lisa Macon; Randolph, Greg D

2012-01-01

This case study describes a local home health and hospice agency's effort to implement Lean principles and Kaizen methodology as a rapid improvement approach to quality improvement. The agency created a cross-functional team, followed Lean Kaizen methodology, and made significant improvements in scheduling time for home health nurses that resulted in reduced operational costs, improved working conditions, and multiple organizational efficiencies.

Rapid surveillance for health events following a mass meningococcal B vaccine program in a university setting: A Canadian Immunization Research Network study.

Science.gov (United States)

Langley, J M; MacDougall, D M; Halperin, B A; Swain, A; Halperin, S A; Top, K A; McNeil, S A; MacKinnon-Cameron, D; Marty, K; De Serres, G; Dubé, E; Bettinger, J A

2016-07-25

An outbreak of Neisseria meningitidis serotype B infection occurred at a small residential university; public health announced an organizational vaccination program with the 4-component Meningococcal B (4CMenB) vaccine (Bexsero(TM), Novartis/GlaxoSmithKline Inc.) several days later. Since there were limited published data on reactogenicity of 4CMenB in persons over 17years of age, this study sought to conduct rapid surveillance of health events in vaccinees and controls using an online survey. Vaccine uptake was 84.7% for dose 1 (2967/3500) and 70% (2456/3500) for dose 2; the survey response rates were 33.0% (987/2967) and 18.7% (459/2456) in dose 1 and dose 1 recipients respectively, and 12% in unvaccinated individuals (63/533). Most students were 20-29years of age (vaccinees, 64.0%; controls, 74.0). A new health problem or worsening of an existing health problem was reported by 30.0% and 30.3% of vaccine recipients after doses 1 and 2 respectively; and by 15.9% of controls. These health problems interfered with the ability to perform normal activities in most vaccinees reporting these events (74.7% post dose 1; 62.6% post dose 2), and in 60% of controls. The health problems led to a health care provider visit (including emergency room) in 12.8% and 14.4% of vaccinees post doses 1 and 2, respectively and in 40% of controls. The most common reactions in vaccinees were injection site reactions (20.6% post dose 1, 16.1% post dose 20 and non-specific systemic complaints (22.6% post dose 1, 17.6% post dose 2). No hospitalizations were reported. An online surveillance program during an emergency meningococcal B vaccine program was successfully implemented, and detected higher rates of health events in vaccinees compared to controls, and high rates of both vaccinees and controls seeking medical attention. The types of adverse events reported by young adult vaccinees were consistent with those previously. Copyright © 2016 Elsevier Ltd. All rights reserved.

E-DECIDER Rapid Response to the M 6.0 South Napa Earthquake

Science.gov (United States)

Glasscoe, M. T.; Parker, J. W.; Pierce, M. E.; Wang, J.; Eguchi, R. T.; Huyck, C. K.; Hu, Z.; Chen, Z.; Yoder, M. R.; Rundle, J. B.; Rosinski, A.

2014-12-01

E-DECIDER initiated rapid response mode when the California Earthquake Clearinghouse was activated the morning following the M6 Napa earthquake. Data products, including: 1) rapid damage and loss estimates, 2) deformation magnitude and slope change maps, and 3) aftershock forecasts were provided to the Clearinghouse partners within 24 hours of the event via XchangeCore Web Service Data Orchestration sharing. NASA data products were provided to end-users via XchangeCore, EERI and Clearinghouse websites, and ArcGIS online for Napa response, reaching a wide response audience. The E-DECIDER team helped facilitate rapid delivery of NASA products to stakeholders and participated in Clearinghouse Napa earthquake briefings to update stakeholders on product information. Rapid response products from E-DECIDER can be used to help prioritize response efforts shortly after the event has occurred. InLET (Internet Loss Estimation Tool) post-event damage and casualty estimates were generated quickly after the Napa earthquake. InLET provides immediate post-event estimates of casualties and building damage by performing loss/impact simulations using USGS ground motion data and FEMA HAZUS damage estimation technology. These results were provided to E-DECIDER by their collaborators, ImageCat, Inc. and the Community Stakeholder Network (CSN). Strain magnitude and slope change maps were automatically generated when the Napa earthquake appeared on the USGS feed. These maps provide an early estimate of where the deformation has occurred and where damage may be localized. Using E-DECIDER critical infrastructure overlays with damage estimates, decision makers can direct response effort that can be verified later with field reconnaissance and remote sensing-based observations. Earthquake aftershock forecast maps were produced within hours of the event. These maps highlight areas where aftershocks are likely to occur and can also be coupled with infrastructure overlays to help direct response

Analysis of Rapidly Developing Low Cloud Ceilings in a Stable Environment

Science.gov (United States)

Bauman, William H., III; Barrett, Joe H., III; Case, Jonathan L.; Wheeler, Mark M.; Baggett, G. Wayne

2006-01-01

Forecasters at the Space Meteorology Group (SMG) issue 30 to 90 minute forecasts for low cloud ceilings at the Space Shuttle Landing Facility (TTS) to support Space Shuttle landings. Mission verification statistics have shown ceilings to be the number one forecast challenge for SMG. More specifically, forecasters at SMG are concerned with any rapidly developing clouds/ceilings below 8000 ft in a stable, capped thermodynamic environment. Therefore, the Applied Meteorology Unit (AMU) was tasked to examine archived events of rapid stable cloud formation resulting in ceilings below 8000 ft, and document the atmospheric regimes favoring this type of cloud development. The AMU examined the cool season months of November to March during the years of 1993-2003 for days that had low-level inversions and rapid, stable low cloud formation that resulted in ceilings violating the Space Shuttle Flight Rules. The AMU wrote and modified existing code to identify inversions from the morning (-10 UTC) Cape Canaveral, FL rawinsonde (XMR) during the cool season and output pertinent sounding information. They parsed all days with cloud ceilings below 8000 ft at TTS, forming a database of possible rapidly-developing low ceiling events. Days with precipitation or noticeable fog burn-off situations were excluded from the database. In the first phase of this work, only the daytime hours were examined for possible ceiling development events since low clouds are easier to diagnose with visible satellite imagery. Phase II of this work includes expanding the database to include nighttime cases which is underway as this abstract is being written. For the nighttime cases, the AMU will analyze both the 00 UTC soundings and the 10 UTC soundings to examine those data for the presence of a low-level inversion. The 00 UTC soundings will probably not have a surface-based inversion, but the presence of inversions or "neutral" layers aloft and below 8,000 ft will most likely help define the stable

Controlled free radical attack in the apoplast: a hypothesis for roles of O, N and S species in regulatory and polysaccharide cleavage events during rapid abscission by Azolla.

Science.gov (United States)

Cohen, Michael F; Gurung, Sushma; Fukuto, Jon M; Yamasaki, Hideo

2014-03-01

Shedding of organs by abscission is a key terminal step in plant development and stress responses. Cell wall (CW) loosening at the abscission zone can occur through a combination chain breakage of apoplastic polysaccharides and tension release of cellulose microfibrils. Two distinctly regulated abscission cleavage events are amenable to study in small water ferns of the genus Azolla; one is a rapid abscission induced by environmental stimuli such as heat or chemicals, and the other is an ethylene-induced process occurring more slowly through the action of hydrolytic enzymes. Although free radicals are suggested to be involved in the induction of rapid root abscission, its mechanism is not fully understood. The apoplast contains peroxidases, metal-binding proteins and phenolic compounds that potentially generate free radicals from H2O2 to cleave polysaccharides in the CW and middle lamella. Effects of various thiol-reactive agents implicate the action of apoplastic peroxidases having accessible cysteine thiols in rapid abscission. The Ca(2+) dependency of rapid abscission may reflect the stabilization Ca(2+) confers to peroxidase structure and binding to pectin. To spur further investigation, we present a hypothetical model for small signaling molecules H2O2 and NO and their derivatives in regulating, via modification of putative protein thiols, free radical attack of apoplastic polysaccharides. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Management of lipid-lowering therapy in patients with cardiovascular events in the UK: a retrospective cohort study.

Science.gov (United States)

Danese, Mark D; Gleeson, Michelle; Kutikova, Lucie; Griffiths, Robert I; Khunti, Kamlesh; Seshasai, Sreenivasa Rao Kondapally; Ray, Kausik K

2017-05-10

To describe low-density lipoprotein (LDL) cholesterol management and lipid-lowering treatment patterns in patients with a cardiovascular (CV) event. Retrospective cohort study using Clinical Practice Research Datalink records linked with Hospital Episode Statistics data. Routine clinical practice in the UK from 2006 to 2012. Individuals ≥18 years were selected at their first CV-related hospitalisation (first event cohort) if they had received ≥2 lipid-lowering therapy prescriptions within 180 days beforehand. Patients were stratified into four mutually exclusive subgroups based on the presence or absence of vascular disease and of diabetes. Those with a second CV hospitalisation within 36 months were included in a separate cohort (second event cohort). LDL levels in the year prior to the CV event and 12 months later as well as measures of adherence to lipid-lowering therapy during the 12 months after the CV hospitalisation. There were 24 093 patients in the first event cohort, of whom 5274 were included in the second event cohort. Most received moderate intensity statins at baseline and 12 months. Among the four first event cohort subgroups at baseline, the proportions with an LDL of event cohort (31%). An incremental 5% to 9% had an LDL below 1.8 mmol/L at 12 months, suggesting intensification of therapy. The proportion of adherent patients (medication possession ratio of≥0.8) was highest for statins, ranging from 68% to 72%. For ezetimibe, the range was 65% to 70%, and for fibrates, it was 48% to 62%. Despite the existence of effective therapies for lowering cholesterol, patients do not reach achievable LDL targets. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Intensification of oily waste waters purification by means of liquid atomization

Science.gov (United States)

Eskin, A. A.; Tkach, N. S.; Kim, M. I.; Zakharov, G. A.

2017-10-01

In this research, a possibility of using liquid atomization for improving the efficiency of purification of wastewater by different methods has been studied. By the introduced method and an experimental setup for wastewater purification, saturation rate increases with its purification by means of dissolved air flotation. Liquid atomization under excess pressure allows to gain a large interfacial area between the saturated liquid and air, which may increase the rate of purified liquid saturation almost twice, compared to the existing methods of saturation. Current disadvantages of liquid atomization used for intensification of wastewater purification include high energy cost and secondary emulsion of polluting agents. It is also known that by means of liquid atomization a process of ozonizing can be intensified. Large contact surface between the purified liquid and ozone-air mixture increases the oxidizing efficiency, which allows to diminish ozone discharge. Liquid atomization may be used for purification of wastewaters by ultraviolet radiation. Small drops of liquid will be proportionally treated by ultraviolet, which makes it possible to do purification even of turbid wastewaters. High-speed liquid motion will prevent the pollution of quartz tubes of ultraviolet lamps.

Neoadjuvant treatment intensification or adjuvant chemotherapy for locally advanced carcinoma rectum: The optimum treatment approach remains unresolved.

Science.gov (United States)

Mallick, Supriya; Benson, Rony; Haresh, K P; Rath, G K

2015-12-01

Rectal carcinoma [RC] is often managed with preoperative radiotherapy or radio-chemotherapy followed by total mesorectal excision (TME). Efforts are being made to improve outcome by intensifying the preoperative treatment. However, the optimum therapy remains unclear. There is ongoing controversy regarding the optimum radiation dose, chemotherapy regimen and schedule. In addition there exists growing disagreement regarding the role of adjuvant chemotherapy after neoadjuvant radiation or chemoradiation. We reviewed the recent land mark trials to find a road map in the management of locally advanced rectal carcinoma. Preoperative short course radiotherapy has long been proven to improve local disease control. The initial trials with long course chemoradiotherapy, comparing short course radiotherapy have shown to increase local control and pathological complete response rates. Since then treatment intensification of this neoadjuvant schedule has been tried by many researchers. But initial results of these treatment intensification trials, show no significant benefit and are associated with increased toxicity. There is an unmet need to stratify patients depending on risk to assign them to long course chemoradiotherapy or short course radiotherapy. Current evidence does not support the use of adjuvant chemotherapy in patients who were treated with preoperative (chemo)radiotherapy. Preoperative radiotherapy appears to improve disease control with favorable toxicity profile and there is very little to choose between long course chemoradiotherapy and short course radiotherapy. However, long course chemoradiotherapy may be beneficial for patients with high risk features like positive circumferential resection margin [CRM] and extramural spread of >5mm. There is no role for adjuvant chemotherapy in patients who were treated preoperative (chemo)radiotherapy. Copyright © 2015 The Authors. Production and hosting by Elsevier B.V. All rights reserved.

Neoadjuvant treatment intensification or adjuvant chemotherapy for locally advanced carcinoma rectum: The optimum treatment approach remains unresolved

International Nuclear Information System (INIS)

Mallick, S.; Benson, R.; Haresh, K.P.; Rath, G.K.

2015-01-01

Background: Rectal carcinoma [RC] is often managed with preoperative radiotherapy or radio chemotherapy followed by total meso rectal excision (TME). Efforts are being made to improve outcome by intensifying the preoperative treatment. However, the optimum therapy remains unclear. There is ongoing controversy regarding the optimum radiation dose, chemotherapy regimen and schedule. In addition there exists growing disagreement regarding the role of adjuvant chemotherapy after neoadjuvant radiation or chemo radiation. Methodology: We reviewed the recent land mark trials to find a road map in the management of locally advanced rectal carcinoma. Results: Preoperative short course radiotherapy has long been proven to improve local disease con- trol. The initial trials with long course chemoradiotherapy, comparing short course radiotherapy have shown to increase local control and pathological complete response rates. Since then treatment intensification of this neoadjuvant schedule has been tried by many researchers. But initial results of these treatment intensification trials, show no significant benefit and are associated with increased toxicity. There is an unmet need to stratify patients depending on risk to assign them to long course chemoradiotherapy or short course radiotherapy. Current evidence does not support the use of adjuvant chemotherapy in patients who were treated with preoperative (chemo)radiotherapy. Conclusion: Preoperative radiotherapy appears to improve disease control with favorable toxicity profile and there is very little to choose between long course chemoradiotherapy and short course radiotherapy. However, long course chemoradiotherapy may be beneficial for patients with high risk features like positive circumferential resection margin [CRM] and extramural spread of >5 mm. There is no role for adjuvant chemotherapy in patients who were treated preoperative (chemo)radiotherapy

Intensification of the amethyst color by irradiation; Intensificacao da cor de ametista por irradiacao

Energy Technology Data Exchange (ETDEWEB)

Gorski, Maria Silvia [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil)

2000-07-01

Brazil is great natural quartz producer. Amethyst, variety of the violet color is very appreciated in the world and since the Antiquity it is said to have many supernatural powers. Is the most highly valued stone in the quartz group and the graduation of the color is responsible for the commercial value that varies of US$ 0.5 to US$ 25.0 for carat. As carried through studies the violet color is related with the amount of Fe{sup 4+} distributed in the crystal . The present work consists of the induction and intensification of the violet color by rays gamma of sources of Co-60 in quartz samples of diverse origins. It was used analyses by fluorescence for X-rays in samples of amethyst and citrine for the evaluation of the the iron and aluminium for the induction of the violet color. (author)

Intensification and deepening of the Arabian Sea oxygen minimum zone in response to increase in Indian monsoon wind intensity

Science.gov (United States)

Lachkar, Zouhair; Lévy, Marina; Smith, Shafer

2018-01-01

The decline in oxygen supply to the ocean associated with global warming is expected to expand oxygen minimum zones (OMZs). This global trend can be attenuated or amplified by regional processes. In the Arabian Sea, the world's thickest OMZ is highly vulnerable to changes in the Indian monsoon wind. Evidence from paleo-records and future climate projections indicates strong variations of the Indian monsoon wind intensity over climatic timescales. Yet, the response of the OMZ to these wind changes remains poorly understood and its amplitude and timescale unexplored. Here, we investigate the impacts of perturbations in Indian monsoon wind intensity (from -50 to +50 %) on the size and intensity of the Arabian Sea OMZ, and examine the biogeochemical and ecological implications of these changes. To this end, we conducted a series of eddy-resolving simulations of the Arabian Sea using the Regional Ocean Modeling System (ROMS) coupled to a nitrogen-based nutrient-phytoplankton-zooplankton-detritus (NPZD) ecosystem model that includes a representation of the O2 cycle. We show that the Arabian Sea productivity increases and its OMZ expands and deepens in response to monsoon wind intensification. These responses are dominated by the perturbation of the summer monsoon wind, whereas the changes in the winter monsoon wind play a secondary role. While the productivity responds quickly and nearly linearly to wind increase (i.e., on a timescale of years), the OMZ response is much slower (i.e., a timescale of decades). Our analysis reveals that the OMZ expansion at depth is driven by increased oxygen biological consumption, whereas its surface weakening is induced by increased ventilation. The enhanced ventilation favors episodic intrusions of oxic waters in the lower epipelagic zone (100-200 m) of the western and central Arabian Sea, leading to intermittent expansions of marine habitats and a more frequent alternation of hypoxic and oxic conditions there. The increased

Intensification and deepening of the Arabian Sea oxygen minimum zone in response to increase in Indian monsoon wind intensity

Directory of Open Access Journals (Sweden)

Z. Lachkar

2018-01-01

Full Text Available The decline in oxygen supply to the ocean associated with global warming is expected to expand oxygen minimum zones (OMZs. This global trend can be attenuated or amplified by regional processes. In the Arabian Sea, the world's thickest OMZ is highly vulnerable to changes in the Indian monsoon wind. Evidence from paleo-records and future climate projections indicates strong variations of the Indian monsoon wind intensity over climatic timescales. Yet, the response of the OMZ to these wind changes remains poorly understood and its amplitude and timescale unexplored. Here, we investigate the impacts of perturbations in Indian monsoon wind intensity (from −50 to +50 % on the size and intensity of the Arabian Sea OMZ, and examine the biogeochemical and ecological implications of these changes. To this end, we conducted a series of eddy-resolving simulations of the Arabian Sea using the Regional Ocean Modeling System (ROMS coupled to a nitrogen-based nutrient–phytoplankton–zooplankton–detritus (NPZD ecosystem model that includes a representation of the O2 cycle. We show that the Arabian Sea productivity increases and its OMZ expands and deepens in response to monsoon wind intensification. These responses are dominated by the perturbation of the summer monsoon wind, whereas the changes in the winter monsoon wind play a secondary role. While the productivity responds quickly and nearly linearly to wind increase (i.e., on a timescale of years, the OMZ response is much slower (i.e., a timescale of decades. Our analysis reveals that the OMZ expansion at depth is driven by increased oxygen biological consumption, whereas its surface weakening is induced by increased ventilation. The enhanced ventilation favors episodic intrusions of oxic waters in the lower epipelagic zone (100–200 m of the western and central Arabian Sea, leading to intermittent expansions of marine habitats and a more frequent alternation of hypoxic and oxic conditions there

Rapid scanning system for fuel drawers

International Nuclear Information System (INIS)

Caldwell, J.T.; Fehlau, P.E.; France, S.W.

1981-01-01

A nondestructive method for uniqely distinguishing among and quantifying the mass of individual fuel plates in situ in fuel drawers utilized in nuclear reactors is described. The method is both rapid and passive, eliminating the personnel hazard of the commonly used irradiation techniques which require that the analysis be performed in proximity to an intense neutron source such as a reactor. In the present technique, only normally decaying nuclei are observed. This allows the analysis to be performed anywhere. This feature, combined with rapid scanning of a given fuel drawer (in approximately 30 s), and the computer data analysis allows the processing of large numbers of fuel drawers efficiently in the event of a loss alert

Do ENSO and Coastal Development Enhance Coastal Burial of Terrestrial Carbon?

Science.gov (United States)

Macreadie, Peter I; Rolph, Timothy C; Boyd, Ron; Schröder-Adams, Claudia J; Skilbeck, Charles G

2015-01-01

Carbon cycling on the east coast of Australia has the potential to be strongly affected by El Niño-Southern Oscillation (ENSO) intensification and coastal development (industrialization and urbanization). We performed paleoreconstructions of estuarine sediments from a seagrass-dominated estuary on the east coast of Australia (Tuggerah Lake, New South Wales) to test the hypothesis that millennial-scale ENSO intensification and European settlement in Australia have increased the transfer of organic carbon from land into coastal waters. Our data show that carbon accumulation rates within coastal sediments increased significantly during periods of maximum millennial-scale ENSO intensity ("super-ENSO") and coastal development. We suggest that ENSO and coastal development destabilize and liberate terrestrial soil carbon, which, during rainfall events (e.g., La Niña), washes into estuaries and becomes trapped and buried by coastal vegetation (seagrass in this case). Indeed, periods of high carbon burial were generally characterized as having rapid sedimentation rates, higher content of fine-grained sediments, and increased content of wood and charcoal fragments. These results, though preliminary, suggest that coastal development and ENSO intensification--both of which are predicted to increase over the coming century--can enhance capture and burial of terrestrial carbon by coastal ecosystems. These findings have important relevance for current efforts to build an understanding of terrestrial-marine carbon connectivity into global carbon budgets.

Will intensification of beef production deliver conservation outcomes in the Brazilian Amazon?

Directory of Open Access Journals (Sweden)

Frank Merry

2017-05-01

Full Text Available The intensification of beef production has become a conservation target based on the idea of land sparing and the assumption that in order to contain deforestation and meet increasing beef demand we must increase productivity. There is also increasing attention and conservation credit being given to supply chain management in beef production. Based on a historical comparison between the US, a fully intensive system, and Brazil, one moving in that direction, we suggest that cattle ranching will intensify as a result of conservation investments (reductions in capital and land subsidies rather than intensifying in order to produce conservation results. If the comparison holds, the new intensive system, however, will continue to require large natural resource inputs, government subsidies, and be plagued by social and conservation problems. It will also be held in thrall by a few large processing companies, which exert undue influence over both producers and consumers. Therefore, we suggest that closer attention be paid to attribution in the claim of conservation outcomes from intensive beef production.

Process intensification of biodiesel production by using microwave and ionic liquids as catalyst

International Nuclear Information System (INIS)

Handayani, Prima Astuti; Abdullah; Hadiyanto, Dan

2015-01-01

The energy crisis pushes the development and intensification of biodiesel production process. Biodiesel is produced by transesterification of vegetable oils or animal fats and conventionally produced by using acid/base catalyst. However, the conventional method requires longer processing time and obtains lower yield of biodiesel. The microwave has been intensively used to accelerate production process and ionic liquids has been introduced as source of catalyst. This paper discusses the overview of the development of biodiesel production through innovation using microwave irradiation and ionic liquids catalyst to increase the yield of biodiesel. The potential microwave to reduce the processing time will be discussed and compared with other energy power, while the ionic liquids as a new generation of catalysts in the chemical industry will be also discussed for its use. The ionic liquids has potential to enhance the economic and environmental aspects because it has a low corrosion effect, can be recycled, and low waste form

Process intensification of biodiesel production by using microwave and ionic liquids as catalyst

Energy Technology Data Exchange (ETDEWEB)

Handayani, Prima Astuti [Department of Chemical Engineering, Diponegoro University (Indonesia); Chemical Engineering Program, Faculty of Engineering, Semarang State University (Indonesia); Abdullah; Hadiyanto, Dan, E-mail: hadiyanto@live.undip.ac.id [Department of Chemical Engineering, Diponegoro University (Indonesia)

2015-12-29

The energy crisis pushes the development and intensification of biodiesel production process. Biodiesel is produced by transesterification of vegetable oils or animal fats and conventionally produced by using acid/base catalyst. However, the conventional method requires longer processing time and obtains lower yield of biodiesel. The microwave has been intensively used to accelerate production process and ionic liquids has been introduced as source of catalyst. This paper discusses the overview of the development of biodiesel production through innovation using microwave irradiation and ionic liquids catalyst to increase the yield of biodiesel. The potential microwave to reduce the processing time will be discussed and compared with other energy power, while the ionic liquids as a new generation of catalysts in the chemical industry will be also discussed for its use. The ionic liquids has potential to enhance the economic and environmental aspects because it has a low corrosion effect, can be recycled, and low waste form.

Event-based plausibility immediately influences on-line language comprehension.

Science.gov (United States)

Matsuki, Kazunaga; Chow, Tracy; Hare, Mary; Elman, Jeffrey L; Scheepers, Christoph; McRae, Ken

2011-07-01

In some theories of sentence comprehension, linguistically relevant lexical knowledge, such as selectional restrictions, is privileged in terms of the time-course of its access and influence. We examined whether event knowledge computed by combining multiple concepts can rapidly influence language understanding even in the absence of selectional restriction violations. Specifically, we investigated whether instruments can combine with actions to influence comprehension of ensuing patients of (as in Rayner, Warren, Juhuasz, & Liversedge, 2004; Warren & McConnell, 2007). Instrument-verb-patient triplets were created in a norming study designed to tap directly into event knowledge. In self-paced reading (Experiment 1), participants were faster to read patient nouns, such as hair, when they were typical of the instrument-action pair (Donna used the shampoo to wash vs. the hose to wash). Experiment 2 showed that these results were not due to direct instrument-patient relations. Experiment 3 replicated Experiment 1 using eyetracking, with effects of event typicality observed in first fixation and gaze durations on the patient noun. This research demonstrates that conceptual event-based expectations are computed and used rapidly and dynamically during on-line language comprehension. We discuss relationships among plausibility and predictability, as well as their implications. We conclude that selectional restrictions may be best considered as event-based conceptual knowledge rather than lexical-grammatical knowledge.

Study the Precipitation of Radiation Belt Electrons during the Rapid Dropout Events

Science.gov (United States)

Tu, W.; Cunningham, G.; Li, X.; Chen, Y.

2015-12-01

During the main phase of storms, the relativistic electron flux in the radiation belt can drop by orders of magnitude on timescales of a few hours. Where do the electrons go? This is one of the most important outstanding questions in radiation belt studies. Radiation belt electrons can be lost either by transport across the magnetopause into interplanetary space or by precipitation into the atmosphere. In this work we first conduct a survey of the MeV electron dropouts using the Van Allen Probes data in conjunction with the low-altitude measurements of precipitating electrons by 6 NOAA/POES satellites. The dropout events are categorized into three types: precipitation-loss dominant, outward radial diffusion dominant, or with contributions from both mechanisms. The survey results suggest the relative importance of precipitation and outward radial diffusion to the fast dropouts of radiation belt electrons, and their extent in L-shell and electron energy. Then, for specific events identified as dominated by precipitation loss, we use the Drift-Diffusion model, which includes the effects of azimuthal drift and pitch angle diffusion, to simulate both the electron dropout observed by Van Allen Probes and the distributions of drift-loss-cone electrons observed by multiple low-earth-orbit satellites (6 POES and the Colorado Student Space Weather Experiment). The model quantifies the electron precipitation loss and pitch angle diffusion coefficient, Dxx, with high temporal and spatial resolution. Finally, by comparing the Dxx derived from the model with those estimated from the quasi-linear theory using wave data from Van Allen Probes and other event-specific wave models, we are able to test the validity of quasi-linear theory and seek direct evidence of the wave-particle interactions during the dropouts.

Déterminants économiques et sociaux de choix de la culture cotonnière et de son intensification dans un contexte de crise de la filière en Centrafrique

Directory of Open Access Journals (Sweden)

Mbétid-Bessane, E.

2010-01-01

Full Text Available Economic and Social Determinants of the Cotton Culture Choice and its Intensification in a Context of Crisis of the Sector in the Central African Republic. The cotton farms in crisis, because of the decrease of the price of cotton and the increase in prices of the inputs, develop various adaptive strategies: some abandoned cotton or reduced its surface to develop the strategies of livestock, marketed oriented foodstuffs or diversification of the activities but others develop the intensive cotton strategy. The objective of the paper is to find out the determinants of the cotton cultural choice and its intensification during the crisis and to propose some support to the producers. To reach this objective, econometric analyses are conducted based on surveys of 350 farms. The results show that the economic and social variables have a positive impact on the probability of cotton choice in the situation of crisis. The analysis of the sensitivity of this probability shows that the economic variables have the strongest marginal effects. As for the intensification, the results show that the social variable as experience in cotton cultivation and the economic variables are determinants in the period of crisis. Thus, the large size farms, having a long experience in cotton, develop the intensive cotton strategy during the crisis. Support for accompanying this strategy in a period of crisis would improve the results of these farms.

Risks and Benefits of Rapid Clozapine Titration.

Science.gov (United States)

Lochhead, Jeannie D; Nelson, Michele A; Schneider, Alan L

2016-05-18

Clozapine is often considered the gold standard for the treatment of schizophrenia. Clinical guidelines suggest a gradual titration over 2 weeks to reduce the risks of adverse events such as seizures, hypotension, agranulocytosis, and myocarditis. The slow titration often delays time to therapeutic response. This raises the question of whether, in some patients, it may be safe to use a more rapid clozapine titration. The following case illustrates the potential risks associated with the use of multiple antipsychotics and rapid clozapine titration. We present the case of a young man with schizophrenia who developed life threatening neuroleptic malignant syndrome (NMS) during rapid clozapine titration and treatment with multiple antipsychotics. We were unable to find another case in the literature of NMS associated with rapid clozapine titration. This case is meant to urge clinicians to carefully evaluate the risks and benefits of rapid clozapine titration, and to encourage researchers to further evaluate the safety of rapid clozapine titration. Rapid clozapine titration has implications for decreasing health care costs associated with prolonged hospitalizations, and decreasing the emotional suffering associated with uncontrolled symptoms of psychosis. Clozapine is considered the most effective antipsychotic available thus efforts should focus on developing strategies that would allow for safest and most efficient use of clozapine to encourage its utilization for treatment resistance schizophrenia.

Risks and benefits of rapid clozapine titration

Directory of Open Access Journals (Sweden)

Jeannie D. Lochhead

2016-05-01

Full Text Available Clozapine is often considered the gold standard for the treatment of schizophrenia. Clinical guidelines suggest a gradual titration over 2 weeks to reduce the risks of adverse events such as seizures, hypotension, agranulocytosis, and myocarditis. The slow titration often delays time to therapeutic response. This raises the question of whether, in some patients, it may be safe to use a more rapid clozapine titration. The following case illustrates the potential risks associated with the use of multiple antipsychotics and rapid clozapine titration. We present the case of a young man with schizophrenia who developed life threatening neuroleptic malignant syndrome (NMS during rapid clozapine titration and treatment with multiple antipsychotics. We were unable to find another case in the literature of NMS associated with rapid clozapine titration. This case is meant to urge clinicians to carefully evaluate the risks and benefits of rapid clozapine titration, and to encourage researchers to further evaluate the safety of rapid clozapine titration. Rapid clozapine titration has implications for decreasing health care costs associated with prolonged hospitalizations, and decreasing the emotional suffering associated with uncontrolled symptoms of psychosis. Clozapine is considered the most effective antipsychotic available thus efforts should focus on developing strategies that would allow for safest and most efficient use of clozapine to encourage its utilization for treatment resistance schizophrenia.

RAPIDLY RISING TRANSIENTS IN THE SUPERNOVA—SUPERLUMINOUS SUPERNOVA GAP

Energy Technology Data Exchange (ETDEWEB)

Arcavi, Iair; Howell, D. Andrew [Las Cumbres Observatory Global Telescope, 6740 Cortona Dr., Suite 102, Goleta, CA 93111 (United States); Wolf, William M. [Department of Physics, University of California, Santa Barbara, CA 93106 (United States); Bildsten, Lars; McCully, Curtis; Valenti, Stefano [Kavli Institute for Theoretical Physics, University of California, Santa Barbara, CA 93106 (United States); Leloudas, Giorgos; Gal-Yam, Avishay; Katz, Boaz [Department of Particle Physics and Astrophysics, The Weizmann Institute of Science, Rehovot, 76100 (Israel); Hardin, Delphine; Astier, Pierre; Balland, Cristophe [LPNHE, CNRS-IN2P3 and University of Paris VI and VII, F-75005 Paris (France); Prajs, Szymon; Sullivan, Mark [School of Physics and Astronomy, University of Southampton, Southampton, SO17 1BJ (United Kingdom); Perley, Daniel A. [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen (Denmark); Svirski, Gilad [Racah Institute for Physics, The Hebrew University, Jerusalem 91904 (Israel); Cenko, S. Bradley [Astrophysics Science Division, NASA Goddard Space Flight Center, Mail Code 661, Greenbelt, MD 20771 (United States); Lidman, Chris [Australian Astronomical Observatory, P.O. Box 915, North Ryde, NSW 1670 (Australia); Carlberg, Ray G. [Department of Astronomy and Astrophysics, University of Toronto, 50 St. George Street, Toronto, ON M5S 3H8 (Canada); Conley, Alex, E-mail: iarcavi@lcogt.net [Center for Astrophysics and Space Astronomy, University of Colorado, 389 UCB, Boulder, CO 80309-389 (United States); and others

2016-03-01

We present observations of four rapidly rising (t{sub rise} ≈ 10 days) transients with peak luminosities between those of supernovae (SNe) and superluminous SNe (M{sub peak} ≈ −20)—one discovered and followed by the Palomar Transient Factory (PTF) and three by the Supernova Legacy Survey. The light curves resemble those of SN 2011kl, recently shown to be associated with an ultra-long-duration gamma-ray burst (GRB), though no GRB was seen to accompany our SNe. The rapid rise to a luminous peak places these events in a unique part of SN phase space, challenging standard SN emission mechanisms. Spectra of the PTF event formally classify it as an SN II due to broad Hα emission, but an unusual absorption feature, which can be interpreted as either high velocity Hα (though deeper than in previously known cases) or Si ii (as seen in SNe Ia), is also observed. We find that existing models of white dwarf detonations, CSM interaction, shock breakout in a wind (or steeper CSM), and magnetar spin down cannot readily explain the observations. We consider the possibility that a “Type 1.5 SN” scenario could be the origin of our events. More detailed models for these kinds of transients and more constraining observations of future such events should help to better determine their nature.

JINR rapid communications

International Nuclear Information System (INIS)

1999-01-01

The present collection of rapid communications from JINR, Dubna, contains seven separate records on measurements of the total cross section difference Δσ L (np) at 1.59, 1.79, and 2.20 GeV, to the estimation of angular distributions of double charged spectator fragments in nucleus-nucleus interactions at superhigh energies, simulation dE/dx analysis results for silicon inner tracking system of ALICE set-up at LHC accelerator, high-multiplicity processes, triggering of high-multiplicity events using calorimetry, ORBIT-3.0 - a computer code for simulation and correction of the closed orbit and first turn in synchrotrons and determination of memory performance

Coupled C, N and P controls on photosynthesis, primary production and decomposition across a land use intensification gradient and implications for land atmosphere C exchange

Science.gov (United States)

Reinsch, Sabine; Glanville, Helen; Smart, Simon; Jones, Davey; Mercado, Lina; Blanes-Alberola, Mamen; Cosby, Jack; Emmett, Bridget

2016-04-01

The coupling of C, N and P cycles has rarely been studied through the air- land-water continuum. This is essential if we are to enhance land-atmosphere models to account for N and P limitations. It is also important for developing integrated catchment management solutions to deliver improved water quality combined with a wide range of other ecosystem functions and services. We present results from a project which is part of the interdisciplinary pan-UK NERC Macronutrient Cycles Programme (macronutrient-cycles.ouce.ox.ac.uk/). Our aim is to quantify how coupled C, N & P cycles change across a land use intensification gradient from arable to grass, woodland and bog ecosystems and identify the implications for land-atmosphere C exchange. We focus on three key processes; photosynthesis, annual net primary productivity and decomposition and explore their consequences for biodiversity. Other aspects of the project track delivery to, and transformations within, the freshwater and coastal systems. When we explore relationships between C, N and P, results indicate all habitat types fall on a single land use intensification gradient. Stoichiometry suggests plant productivity is primarily N limited. P limitation occurs rarely but at all levels of intensification. Soil priming shows our soils are primarily C limited and, surprisingly, soil acidity provides one of the most powerful single predictors of processes and ecosystem services perhaps as it is a good integrator of many soil properties. Incorporating this knowledge into the UK land-atmosphere model JULES will improve aNPP projections. These are then being used as inputs into a plant species model called MULTIMOVE to enable future scenarios of climate change, land use and air pollution on habitat suitability for > 1400 plant species to be explored. The enhanced Jules model will ensure both N and P limitations on C fluxes from above and below-ground are incorporated into future UK scenario applications.

Ion temperature increase during MHD events on the TST-2 spherical tokamak

International Nuclear Information System (INIS)

Ejiri, A.; Shiraiwa, S.; Takase, Y.; Yamada, T.; Nagashima, Y.; Kasahara, H.; Iijima, D.; Kobori, Y.; Nishi, T.; Taniguchi, T.; Aramasu, M.; Ohara, S.; Ushigome, M.; Yamagishi, K.

2003-01-01

Various types of MHD events including internal reconnection events are studied on the TST-2 spherical tokamak. In weak MHD events no positive current spike was observed, but in strong MHD events with positive current spikes, a rapid and significant impurity ion temperature increase was observed. The decrease in the poloidal magnetic energy is the most probable energy source for ion heating. The plasma current shows a stepwise change. The magnitude of this step correlates with the temperature increase and is found to be a good indicator of the strength of each event. (author)

Effect of a Jurassic oceanic anoxic event on belemnite ecology and evolution

DEFF Research Database (Denmark)

Ullmann, Clemens Vinzenz; Thibault, Nicolas Rudolph; Ruhl, Micha

2014-01-01

The Toarcian oceanic anoxic event (T-OAE; ∼183 million y ago) is possibly the most extreme episode of widespread ocean oxygen deficiency in the Phanerozoic, coinciding with rapid atmospheric pCO2 increase and significant loss of biodiversity in marine faunas. The event is a unique past tipping...... point in the Earth system, where rapid and massive release of isotopically light carbon led to a major perturbation in the global carbon cycle as recorded in organic and inorganic C isotope records. Modern marine ecosystems are projected to experience major loss in biodiversity in response to enhanced...

Maturation of Rapid Auditory Temporal Processing and Subsequent Nonword Repetition Performance in Children

Science.gov (United States)

Fox, Allison M.; Reid, Corinne L.; Anderson, Mike; Richardson, Cassandra; Bishop, Dorothy V. M.

2012-01-01

According to the rapid auditory processing theory, the ability to parse incoming auditory information underpins learning of oral and written language. There is wide variation in this low-level perceptual ability, which appears to follow a protracted developmental course. We studied the development of rapid auditory processing using event-related…

Physical workload, work intensification, and prevalence of pain in low wage workers: results from a participatory research project with hotel room cleaners in Las Vegas.

Science.gov (United States)

Krause, Niklas; Scherzer, Teresa; Rugulies, Reiner

2005-11-01

Occupational injury rates among hotel workers exceed the national service sector average. This study assesses the prevalence of back and neck pain, and its associations with physical workload, ergonomic problems, and increasing work demands. Nine hundred forty-one unionized hotel room cleaners completed a survey about health and working conditions. Associations between job demands and pain were determined by logistic regression models adjusting for individual characteristics, cumulative work demands, care-taking responsibilities at home, and psychosocial job factors. The 1-month prevalence of severe bodily pain was 47% in general, 43% for neck, 59% for upper back, and 63% for low back pain. Workers in the highest exposure quartiles for physical workload and ergonomic problems were between 3.24 and 5.42 times more likely to report severe pain than workers in the lowest quartile. Adjusted odds ratios for work intensification ranged from 1.74 (upper back) to 2.33 (neck). Most room cleaners experience severe back or neck pain. Severe pain showed strong associations with physical workload, work intensification, and ergonomic problems.

Extreme Weather Events and Climate Change Attribution

Energy Technology Data Exchange (ETDEWEB)

Thomas, Katherine [National Academy of Sciences, Washington, DC (United States)

2016-03-31

A report from the National Academies of Sciences, Engineering, and Medicine concludes it is now possible to estimate the influence of climate change on some types of extreme events. The science of extreme event attribution has advanced rapidly in recent years, giving new insight to the ways that human-caused climate change can influence the magnitude or frequency of some extreme weather events. This report examines the current state of science of extreme weather attribution, and identifies ways to move the science forward to improve attribution capabilities. Confidence is strongest in attributing types of extreme events that are influenced by climate change through a well-understood physical mechanism, such as, the more frequent heat waves that are closely connected to human-caused global temperature increases, the report finds. Confidence is lower for other types of events, such as hurricanes, whose relationship to climate change is more complex and less understood at present. For any extreme event, the results of attribution studies hinge on how questions about the event's causes are posed, and on the data, modeling approaches, and statistical tools chosen for the analysis.

Intensity changes in future extreme precipitation: A statistical event-based approach.

Science.gov (United States)

Manola, Iris; van den Hurk, Bart; de Moel, Hans; Aerts, Jeroen

2017-04-01

Short-lived precipitation extremes are often responsible for hazards in urban and rural environments with economic and environmental consequences. The precipitation intensity is expected to increase about 7% per degree of warming, according to the Clausius-Clapeyron (CC) relation. However, the observations often show a much stronger increase in the sub-daily values. In particular, the behavior of the hourly summer precipitation from radar observations with the dew point temperature (the Pi-Td relation) for the Netherlands suggests that for moderate to warm days the intensification of the precipitation can be even higher than 21% per degree of warming, that is 3 times higher than the expected CC relation. The rate of change depends on the initial precipitation intensity, as low percentiles increase with a rate below CC, the medium percentiles with 2CC and the moderate-high and high percentiles with 3CC. This non-linear statistical Pi-Td relation is suggested to be used as a delta-transformation to project how a historic extreme precipitation event would intensify under future, warmer conditions. Here, the Pi-Td relation is applied over a selected historic extreme precipitation event to 'up-scale' its intensity to warmer conditions. Additionally, the selected historic event is simulated in the high-resolution, convective-permitting weather model Harmonie. The initial and boundary conditions are alternated to represent future conditions. The comparison between the statistical and the numerical method of projecting the historic event to future conditions showed comparable intensity changes, which depending on the initial percentile intensity, range from below CC to a 3CC rate of change per degree of warming. The model tends to overestimate the future intensities for the low- and the very high percentiles and the clouds are somewhat displaced, due to small wind and convection changes. The total spatial cloud coverage in the model remains, as also in the statistical

Late Holocene environmental reconstructions and the implications on flood events, typhoon patterns, and agriculture activities in NE Taiwan

Science.gov (United States)

Wang, L.-C.; Behling, H.; Lee, T.-Q.; Li, H.-C.; Huh, C.-A.; Shiau, L.-J.; Chang, Y.-P.

2014-05-01

In this study, we reconstructed the paleoenvironmental changes from a sediment archive of the floodplain lake in Ilan Plain of NE Taiwan on multi-decadal resolution for the last ca. 1900 years. On the basis of pollen and diatom records, we evaluated the record of past vegetation, floods, typhoons and agriculture activities of this area, which is sensitive to the hydrological conditions of the West Pacific. High sedimentation rates with low microfossil preservations reflected multiple flood events and humid climatic conditions during 100-1400 AD. A shortly interrupted dry phase can be found during 940-1010 AD. The driest phase corresponds to the Little Ice Age phase 1 (LIA1, 1400-1620 AD) with less disturbance by flood events, which enhanced the occurrence of wetlands (Cyperaceae) and diatom depositions. Humid phases with frequent typhoons are inferred by high percentages of Lagerstroemia and high ratios of planktonic/benthic diatoms, respectively, during 500-700 AD and Little Ice Age phase 2 (LIA2, 1630-1850 AD). The occurrences of cultivated Poaceae (Oryza) during 1250-1300 AD and the last ~400 years, reflect agriculture activities, which seems to implicate strongly with the environmental stability. Finally, we found flood events which dominated during the El Niño-like stage, but dry events as well as frequent typhoon events happened during the La Niña-like stage. After comparing our results with the reconstructed proxy for tropical hydrological conditions, we suggested that the local hydrology in coastal East Asia were strongly affected by the typhoon-triggered heavy rainfalls which were influenced by the variation of global temperature, expansion of the Pacific warm pool and intensification of ENSO events.

Observation of jet production in deep inelastic scattering with a large rapidity gap at HERA

International Nuclear Information System (INIS)

Doeker, T.

1994-01-01

Events with a large rapidity gap in deep inelastic scattering with Q 2 ≥ 10 GeV 2 have been studied in the ZEUS detector. The properties of these events with W > 140 GeV are consistent with a leading twist diffractive production mechanism. In the laboratory frame, with E jet t ≥ 4 GeV, 159% of the events are of the 1-jet type with negligible 2-jet production. The single jet is back-to-back in azimuth with the scattered electron. No energy now is observed between the jet and the proton direction. With a lower jet transverse energy cut 2-jet production is observed both in the laboratory and the γ * P centre-of-mass systems, demonstrating the presence of hard scattering in the virtual photon proton interactions that give rise to large rapidity gap events

Observation of jet production in deep inelastic scattering with a large rapidity gap a HERA

International Nuclear Information System (INIS)

Derrick, M.; Krakauer, D.; Magill, S.

1994-04-01

Events with a large rapidity gap in deep inelastic scattering with Q 2 ≥10 GeV 2 have been studied in the ZEUS detector. The properties of these events with W>140 GeV are consistent with a leading twist diffractive mechanism. In the laboratory frame, with E T jet ≥4 GeV, 15% of the events are of the 1-jet type with negligible 2-jet production. The single jet is back-to-back in azimuth with the scattered electron. No energy flow is observed between the jet and the proton direction. With a lower jet transverse energy cut 2-jet production is observed both in the laboratory and the γ * p centre-of-mass systems demonstrating the presence of hard scattering in the virtual photon interactions that give rise to large rapidity gap events. (orig.)

Facilitating Follow-up of LIGO–Virgo Events Using Rapid Sky Localization

Energy Technology Data Exchange (ETDEWEB)

Chen, Hsin-Yu [Department of Astronomy and Astrophysics and Kavli Institute for Cosmological Physics, University of Chicago, Chicago, IL 60637 (United States); Holz, Daniel E. [Enrico Fermi Institute, Department of Physics, Department of Astronomy and Astrophysics, and Kavli Institute for Cosmological Physics, University of Chicago, Chicago, IL 60637 (United States)

2017-05-10

We discuss an algorithm for accurate and very low-latency (<1 s) localization of gravitational-wave (GW) sources using only the relative times of arrival, relative phases, and relative signal-to-noise ratios for pairs of detectors. The algorithm is independent of distances and masses to leading order, and can be generalized to all discrete (as opposed to stochastic and continuous) sources detected by ground-based detector networks. Our approach is similar to that of BAYESTAR with a few modifications, which result in increased computational efficiency. For the LIGO two-detector configuration (Hanford+Livingston) operating in O1 we find a median 50% (90%) localization of 143 deg{sup 2} (558 deg{sup 2}) for binary neutron stars. We use our algorithm to explore the improvement in localization resulting from loud events, finding that the loudest out of the first 4 (or 10) events reduces the median sky-localization area by a factor of 1.9 (3.0) for the case of two GW detectors, and 2.2 (4.0) for three detectors. We also consider the case of multi-messenger joint detections in both the gravitational and the electromagnetic radiation, and show that joint localization can offer significant improvements (e.g., in the case of LIGO and Fermi /GBM joint detections). We show that a prior on the binary inclination, potentially arising from GRB observations, has a negligible effect on GW localization. Our algorithm is simple, fast, and accurate, and may be of particular utility in the development of multi-messenger astronomy.

Toward a Competitive Process Intensification: A New Generation of Heat Exchanger-Reactors Vers une intensification des procédés économiquement viable : une nouvelle génération de réacteur-échangeur de chaleur

Directory of Open Access Journals (Sweden)

Tochon P.

2010-10-01

Full Text Available Process Intensification (PI in chemical production is a major concern of chemical manufacturers. Among the numerous options to intensify a process, the transposition from a batch reactor to a continuous plug flow reactor is a good alternative when the selectivity and the thermal exchange are an issue. In this context, the RAPIC R&D project aims to develop an innovative low-cost component (in the 10 kg/h range. This project deals with the design from the local to the global scale and with testing, from elementary mock-ups to pilot scale. The present paper gives a detailed description of this research project and presents the main results on specification and definition of the reaction channel and the first simple mock-ups. L’intensification des procédés (IP constitue une des préoccupations majeures de l’industrie chimique. Parmi les nombreuses options possibles pour intensifier un procédé, lorsque le sujet concerne la sélectivité et l’échange thermique, la transposition d’un réacteur discontinu à un réacteur tubulaire continu paraît une bonne alternative. Dans ce contexte, le projet de R&D RAPIC consiste à développer un composant innovant à bas coût (environ 10 kg/heure. Ce projet porte sur la phase de conception, du niveau local au niveau global, et sur la phase de tests, depuis les maquettes élémentaires jusqu’aux essais pilote. Cet article propose une description détaillée de ce projet de recherche et présente les principaux résultats obtenus sur la définition et la spécification du canal de réaction, ainsi que les premières maquettes simples.

Rapidity distributions in unequal nuclei collision at high energies and hydrodynamical model

International Nuclear Information System (INIS)

Zhuang Pengfei; Wang Zhengqing

1987-01-01

The mechanism of high-energy A'-A collision (A > A', A' 1/3 >> 1) and the space-time evolution of the fluid formed in the collision are analysed. The corresponding 1 + 1 dimensional hydrodynamical equations are established. The average rapidity distributions are estimated and compared with some cosmic ray events. The origin of the nonsymmetry of rapidity distribution is explained

Weakening density dependence from climate change and agricultural intensification triggers pest outbreaks: a 37-year observation of cotton bollworms.

Science.gov (United States)

Ouyang, Fang; Hui, Cang; Ge, Saiying; Men, Xin-Yuan; Zhao, Zi-Hua; Shi, Pei-Jian; Zhang, Yong-Sheng; Li, Bai-Lian

2014-09-01

Understanding drivers of population fluctuation, especially for agricultural pests, is central to the provision of agro-ecosystem services. Here, we examine the role of endogenous density dependence and exogenous factors of climate and human activity in regulating the 37-year population dynamics of an important agricultural insect pest, the cotton bollworm (Helicoverpa armigera), in North China from 1975 to 2011. Quantitative time-series analysis provided strong evidence explaining long-term population dynamics of the cotton bollworm and its driving factors. Rising temperature and declining rainfall exacerbated the effect of agricultural intensification on continuously weakening the negative density dependence in regulating the population dynamics of cotton bollworms. Consequently, ongoing climate change and agricultural intensification unleashed the tightly regulated pest population and triggered the regional outbreak of H. armigera in 1992. Although the negative density dependence can effectively regulate the population change rate to fluctuate around zero at stable equilibrium levels before and after outbreak in the 1992, the population equilibrium jumped to a higher density level with apparently larger amplitudes after the outbreak. The results highlight the possibility for exogenous factors to induce pest outbreaks and alter the population regulating mechanism of negative density dependence and, thus, the stable equilibrium of the pest population, often to a higher level, posing considerable risks to the provision of agro-ecosystem services and regional food security. Efficient and timely measures of pest management in the era of Anthropocene should target the strengthening and revival of weakening density dependence caused by climate change and human activities.

The effect of antiretroviral intensification with dolutegravir on residual virus replication in HIV-infected individuals: a randomised, placebo-controlled, double-blind trial.

Science.gov (United States)

Rasmussen, Thomas A; McMahon, James H; Chang, J Judy; Audsley, Jennifer; Rhodes, Ajantha; Tennakoon, Surekha; Dantanarayana, Ashanti; Spelman, Tim; Schmidt, Tina; Kent, Stephen J; Morcilla, Vincent; Palmer, Sarah; Elliott, Julian H; Lewin, Sharon R

2018-04-06

there were no treatment discontinuations or treatment-related serious adverse events. Our findings show that in HIV-infected individuals on modern suppressive ART regimens, residual replication is rare, if at all present, and was not recorded in blood after dolutegravir intensification. Because tissue biopsies were not done we cannot exclude the possibility of residual virus replication in tissue. Strategies other than ART alone are needed to eliminate HIV persistence on treatment. ViiV Healthcare. Copyright © 2018 Elsevier Ltd. All rights reserved.

Microstructure devices for process intensification: Influence of manufacturing tolerances and design

International Nuclear Information System (INIS)

Brandner, Juergen J.

2013-01-01

Process intensification by miniaturization is a common task for several fields of technology. Starting from manufacturing of electronic devices, miniaturization with the accompanying opportunities and problems gained also interest in chemistry and chemical process engineering. While the integration of enhanced functions, e.g. integrated sensors and actuators, is still under consideration, miniaturization itself has been realized in all material classes, namely metals, ceramics and polymers. First devices have been manufactured by scaling down macro-scale devices. However, manufacturing tolerances, material properties and design show much larger influence to the process than in macro scale. Many of the devices generated alike the macro ones work properly, but possibly could be optimized to a certain extend by adjusting the design and manufacturing tolerances to the special demands of miniaturization. Thus, some considerations on the design and production of devices for micro process engineering should be made to provide devices which show reproducible and controllable process behavior. The aim of the following publication is to show the importance of considerations in manufacturing tolerances and dimensions as well as design of microstructures to avoid negative influences and optimize the process characteristics of miniaturized devices. Some examples will be shown to explain the considerations presented here

No rapid soil carbon loss after a windthrow event in the High Tatra

NARCIS (Netherlands)

Don, A.; Bärwolff, M.; Kalbitz, K.; Andruschkewitsch, R.; Jungkunst, H.F.; Schulze, E.-D.

2012-01-01

Windthrows are among the most important disturbances of forest ecosystems in Europe, with expected increasing frequency due to climate change. However, surprisingly little is known about soil carbon dynamics after windthrow mainly due to missing field assessments. After a large windthrow event in

Physical mechanism causing rapid changes in ultrarelativistic electron pitch angle distributions right after a shock arrival: Evaluation of an electron dropout event

Science.gov (United States)

Zhang, X.-J.; Li, W.; Thorne, R. M.; Angelopoulos, V.; Ma, Q.; Li, J.; Bortnik, J.; Nishimura, Y.; Chen, L.; Baker, D. N.; Reeves, G. D.; Spence, H. E.; Kletzing, C. A.; Kurth, W. S.; Hospodarsky, G. B.; Blake, J. B.; Fennell, J. F.

2016-09-01

Three mechanisms have been proposed to explain relativistic electron flux depletions (dropouts) in the Earth's outer radiation belt during storm times: adiabatic expansion of electron drift shells due to a decrease in magnetic field strength, magnetopause shadowing and subsequent outward radial diffusion, and precipitation into the atmosphere (driven by EMIC wave scattering). Which mechanism predominates in causing electron dropouts commonly observed in the outer radiation belt is still debatable. In the present study, we evaluate the physical mechanism that may be primarily responsible for causing the sudden change in relativistic electron pitch angle distributions during a dropout event observed by Van Allen Probes during the main phase of the 27 February 2014 storm. During this event, the phase space density of ultrarelativistic (>1 MeV) electrons was depleted by more than 1 order of magnitude over the entire radial extent of the outer radiation belt (3 pitch angle distribution under a compressed magnetic field topology based on actual solar wind conditions. Although these ultrarelativistic electrons exhibit highly anisotropic (peaked in 90°), energy-dependent pitch angle distributions, which appear to be associated with the typical EMIC wave scattering, comparison of the modeled electron distribution to electron measurements indicates that drift shell splitting is responsible for this rapid change in electron pitch angle distributions. This further indicates that magnetopause loss is the predominant cause of the electron dropout right after the shock arrival.

JINR rapid communications

International Nuclear Information System (INIS)

1996-01-01

The present collection of rapid communications from JINR, Dubna, contains seven separate reports on the identification of events with a secondary vertex in the experiment EXCHARM, the zero degree calorimeter for CERN WA-98 experiment, a new approach to increase the resource of installation elements for super-high energy physics, a method of the in-flight production of exotic systems in the charge-exchange reactions, the neutron activation analysis for monitoring northern terrestrial ecosystems, a search for 28 O and study of the neutron-rich nuclei near the neutron closure N=20, a search for new neutron-rich nuclei with a 70A MeV 48 Ca beam. 33 figs., 4 tabs

JINR rapid communications

International Nuclear Information System (INIS)

1999-01-01

The present collection of rapid communications from JINR, Dubna, contains seven separate records on yields of the rare-earth neutron-deficient isotopes in the reactions of Mo isotopes with 40 Ca ions, observations of slow components of solitonic-type wave structure excited by e-beam in massive copper sample, development and investigation of low-mass multilayer drift chambers (MDC-2) for inner part of the HADES spectrometer, temperature measurement of the uranium sample irradiated with secondary neutrons, edge effects in multiwire proportional chambers, the influence of the dielectric frame, an object-oriented framework for the hadronic Monte-Carlo event generators and uranium-238 as a source for electronuclear power production. 32 figs., 3 tabs

Tests of Event Filter Configuration Software

CERN Multimedia

Wickens, F.J.

TDAQ - Tests of Event Filter configuration software Within Trigger/DAQ a major consideration is how well the performance of the system components scale in going from the small set-ups used for development work to the final system with many hundreds of processors and links. In the case of the Event Filter, which makes the final stage of on-line event selection, plus on-line calibrations and monitoring, more than a thousand processors are envisaged. These processors will be divided into sub-farms, most will be remote from the detector and some could even be at institutes far from CERN. As part of the on-line system it is important that the software in the sub-farms can be reconfigured rapidly as runs start and stop, and that the system be fault tolerant. The flow of data inside a sub-farm involves many processes, for distribution and collection of results in addition to those for event processing itself. Supervision code written in Java has been developed to manage the processes within a cluster, with XML f...

Higher Moments of Underlying Event Distributions

CERN Document Server

Xu, Zhen

2017-01-01

We perform an Underlying Event analysis for real data sets from pp collisions at center of mass energy $ \\sqrt{s}=5 $ and 13 TeV and pPb collisions at $ \\sqrt{s}=7 $ TeV at the LHC, together with the Monte Carlo data sets generated with Pythia8 and EPOS in the same conditions. The analysis is focused on the transverse region which is more sensitive to the Underlying Event, and performed as a function of the leading track transverse - momentum $p_t$ in each event. In our work, not only the average underlying event activity but also its fluctuation, namely its root mean square (RMS), Skewness and Kurtosis, are analyzed. We find that the particle density, energy density and their fluctuation magnitude (RMS) are suppressed at leading $p_t\\approx$ 5 GeV/c for all these cases, with EPOS having evident deviation of 10\\%-25\\%. The higher moments skewness and kurtosis decrease rapidly in low leading $p_t$ region, and follow an interesting Gaussian-like peak centered at leading $p_t\\approx$ 15 GeV/c.

Low-wave number analysis of observations and ensemble forecasts to develop metrics for the selection of most realistic members to study multi-scale interactions between the environment and the convective organization of hurricanes: Focus on Rapid Intensification

Science.gov (United States)

Hristova-Veleva, S. M.; Chen, H.; Gopalakrishnan, S.; Haddad, Z. S.

2017-12-01

Tropical cyclones (TCs) are the product of complex multi-scale processes and interactions. The role of the environment has long been recognized. However, recent research has shown that convective-scale processes in the hurricane core might also play a crucial role in determining TCs intensity and size. Several studies have linked Rapid Intensification to the characteristics of the convective clouds (shallow versus deep), their organization (isolated versus wide-spread) and their location with respect to dynamical controls (the vertical shear, the radius of maximum wind). Yet a third set of controls signifies the interaction between the storm-scale and large-scale processes. Our goal is to use observations and models to advance the still-lacking understanding of these processes. Recently, hurricane models have improved significantly. However, deterministic forecasts have limitations due to the uncertainty in the representation of the physical processes and initial conditions. A crucial step forward is the use of high-resolution ensembles. We adopt the following approach: i) generate a high resolution ensemble forecast using HWRF; ii) produce synthetic data (e.g. brightness temperature) from the model fields for direct comparison to satellite observations; iii) develop metrics to allow us to sub-select the realistic members of the ensemble, based on objective measures of the similarity between observed and forecasted structures; iv) for these most-realistic members, determine the skill in forecasting TCs to provide"guidance on guidance"; v) use the members with the best predictive skill to untangle the complex multi-scale interactions. We will report on the first three goals of our research, using forecasts and observations of hurricane Edouard (2014), focusing on RI. We will focus on describing the metrics for the selection of the most appropriate ensemble members, based on applying low-wave number analysis (WNA - Hristova-Veleva et al., 2016) to the observed and

Gold Leaching Characteristics and Intensification of a High S and As-Bearing Gold Concentrate

Science.gov (United States)

Yang, Yong-bin; Liu, Xiao-liang; Jiang, Tao; Li, Qian; Xu, Bin; Zhang, Yan

Some high sulfur and arsenic-bearing gold concentrate has a gold leaching rate less than 80% by oxidation roasting-pickling-cyanidation process. The characteristics and intensification of gold leaching were studied systemically. By combining chemical composition and phase analysis, the low gold leaching rate was found to lie in the capsulation of gold by iron-containing phases including iron oxides, arsenopyrite and pyrite. 96.66% of gold in the industrial leaching residue was capsulated and 95.88% of the capsulated turned out to be in the iron-containing phases. The results of laboratory pickling-cyanidation experiments on the calcine and industrial leaching residue presented further demonstration for the fact that gold capsulated in the iron-containing phases was hard to be leached. However, the gold cyanide leaching rate of calcine could be raised over 95% by a reduction roasting-pickling pretreatment which played such a significant role in exposing the capsulated gold that gold leaching was intensified remarkably.

Design of transplanting mechanism for system of rice intensification (SRI) transplanter in Kedah, Malaysia

Science.gov (United States)

Imran, M. S.; Manan, M. S. Abdul; Khalil, A. N. M.; MdNaim, M. K.; Ahmad, R. N.

2017-08-01

There is a demand to develop transplanter specifically for system of rice intensification (SRI) cultivation in Malaysia. This SRI transplanter is different from conventional transplanter as it is required special requirements for transplanting. The work focused on transplanting mechanism design which can be later attached to SRI transplanter. The mechanical design was established using linkage mechanism, having a wheel that act as timing wheel that will control the distance between transplanted seedlings. The linkage mechanism also control the opening of the flapper that allow the seedling together with its nursery soil to be dropped, and control the stopper to prevent next seedling from sliding down the tray. The use of simple mechanism will have low cost for fabrication. The design was analysed using motion analysis software. Results show the design is perfectly good and can be fabricated without any problem. The animation successfully shows the perfect movement of the mechanism and transplanting process.

No evident spatial genetic structuring in the rapidly declining Black-tailed Godwit

NARCIS (Netherlands)

Trimbos, K.B.; Musters, C.J.M.; Verkuil, Y.I.; Kentie, R.; Piersma, T.; De Snoo, G.; Verkuil, Y.I.

2011-01-01

With 40% of the European Black-tailed Godwit population breeding in The Netherlands, this country harbours internationally significant numbers of this species. However, ongoing agricultural intensification has resulted in the fragmentation of the population and drastic population declines since

Measurement of the underlying event in jet events from 7 TeV proton-proton collisions with the ATLAS detector

CERN Document Server

Aad, Georges; Abbott, Brad; Abdallah, Jalal; Abdel Khalek, Samah; Abdinov, Ovsat; Aben, Rosemarie; Abi, Babak; Abolins, Maris; AbouZeid, Ossama; Abramowicz, Halina; Abreu, Henso; Abulaiti, Yiming; Acharya, Bobby Samir; Adamczyk, Leszek; Adams, David; Addy, Tetteh; Adelman, Jahred; Adomeit, Stefanie; Adye, Tim; Agatonovic-Jovin, Tatjana; Aguilar-Saavedra, Juan Antonio; Agustoni, Marco; Ahlen, Steven; Ahmadov, Faig; Aielli, Giulio; Åkesson, Torsten Paul Ake; Akimoto, Ginga; Akimov, Andrei; Albert, Justin; Albrand, Solveig; Alconada Verzini, Maria Josefina; Aleksa, Martin; Aleksandrov, Igor; Alexa, Calin; Alexander, Gideon; Alexandre, Gauthier; Alexopoulos, Theodoros; Alhroob, Muhammad; Alimonti, Gianluca; Alio, Lion; Alison, John; Allbrooke, Benedict; Allison, Lee John; Allport, Phillip; Allwood-Spiers, Sarah; Almond, John; Aloisio, Alberto; Alon, Raz; Alonso, Alejandro; Alonso, Francisco; Alpigiani, Cristiano; Altheimer, Andrew David; Alvarez Gonzalez, Barbara; Alviggi, Mariagrazia; Amako, Katsuya; 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Gordon, Howard; Gorelov, Igor; Gorini, Benedetto; Gorini, Edoardo; Gorišek, Andrej; Gornicki, Edward; Goshaw, Alfred; Gössling, Claus; Gostkin, Mikhail Ivanovitch; Gouighri, Mohamed; Goujdami, Driss; Goulette, Marc Phillippe; Goussiou, Anna; Goy, Corinne; Gozpinar, Serdar; Grabas, Herve Marie Xavier; Graber, Lars; Grabowska-Bold, Iwona; Grafström, Per; Grahn, Karl-Johan; Gramling, Johanna; Gramstad, Eirik; Grancagnolo, Francesco; Grancagnolo, Sergio; Grassi, Valerio; Gratchev, Vadim; Gray, Heather; Graziani, Enrico; Grebenyuk, Oleg; Greenwood, Zeno Dixon; Gregersen, Kristian; Gregor, Ingrid-Maria; Grenier, Philippe; Griffiths, Justin; Grillo, Alexander; Grimm, Kathryn; Grinstein, Sebastian; Gris, Philippe Luc Yves; Grishkevich, Yaroslav; Grivaz, Jean-Francois; Grohs, Johannes Philipp; Grohsjean, Alexander; Gross, Eilam; Grosse-Knetter, Joern; Grossi, Giulio Cornelio; Groth-Jensen, Jacob; Grout, Zara Jane; Grybel, Kai; Guan, Liang; Guescini, Francesco; Guest, Daniel; Gueta, Orel; Guicheney, Christophe; Guido, Elisa; Guillemin, Thibault; Guindon, Stefan; Gul, Umar; Gumpert, Christian; Gunther, Jaroslav; Guo, Jun; Gupta, Shaun; Gutierrez, Phillip; Gutierrez Ortiz, Nicolas Gilberto; Gutschow, Christian; Guttman, Nir; Guyot, Claude; Gwenlan, Claire; Gwilliam, Carl; Haas, Andy; Haber, Carl; Hadavand, Haleh Khani; Haddad, Nacim; Haefner, Petra; Hageböck, Stephan; Hajduk, Zbigniew; Hakobyan, Hrachya; Haleem, Mahsana; Hall, David; Halladjian, Garabed; Hamacher, Klaus; Hamal, Petr; Hamano, Kenji; Hamer, Matthias; Hamilton, Andrew; Hamilton, Samuel; Hamnett, Phillip George; Han, Liang; Hanagaki, Kazunori; Hanawa, Keita; Hance, Michael; Hanke, Paul; Hansen, Jørgen Beck; Hansen, Jorn Dines; Hansen, Peter Henrik; Hara, Kazuhiko; Hard, Andrew; Harenberg, Torsten; Harkusha, Siarhei; Harper, Devin; Harrington, Robert; Harris, Orin; Harrison, Paul Fraser; Hartjes, Fred; Harvey, Alex; Hasegawa, Satoshi; Hasegawa, Yoji; Hasib, A; Hassani, Samira; Haug, Sigve; Hauschild, Michael; Hauser, Reiner; Havranek, Miroslav; Hawkes, Christopher; Hawkings, Richard John; Hawkins, Anthony David; Hayashi, Takayasu; Hayden, Daniel; Hays, Chris; Hayward, Helen; Haywood, Stephen; Head, Simon; Heck, Tobias; Hedberg, Vincent; Heelan, Louise; Heim, Sarah; Heim, Timon; Heinemann, Beate; Heinrich, Lukas; Heisterkamp, Simon; Hejbal, Jiri; Helary, Louis; Heller, Claudio; Heller, Matthieu; Hellman, Sten; Hellmich, Dennis; Helsens, Clement; Henderson, James; Henderson, Robert; Hengler, Christopher; Henrichs, Anna; Henriques Correia, Ana Maria; Henrot-Versille, Sophie; Hensel, Carsten; Herbert, Geoffrey Henry; Hernández Jiménez, Yesenia; Herrberg-Schubert, Ruth; Herten, Gregor; Hertenberger, Ralf; Hervas, Luis; Hesketh, Gavin Grant; Hessey, Nigel; Hickling, Robert; Higón-Rodriguez, Emilio; Hill, John; Hiller, Karl Heinz; Hillert, Sonja; Hillier, Stephen; Hinchliffe, Ian; Hines, Elizabeth; Hirose, Minoru; Hirschbuehl, Dominic; Hobbs, John; Hod, Noam; Hodgkinson, Mark; Hodgson, Paul; Hoecker, Andreas; Hoeferkamp, Martin; Hoffman, Julia; Hoffmann, Dirk; Hofmann, Julia Isabell; Hohlfeld, Marc; Holmes, Tova Ray; Hong, Tae Min; Hooft van Huysduynen, Loek; Hostachy, Jean-Yves; Hou, Suen; Hoummada, Abdeslam; Howard, Jacob; Howarth, James; Hrabovsky, Miroslav; Hristova, Ivana; Hrivnac, Julius; Hryn'ova, Tetiana; Hsu, Pai-hsien Jennifer; Hsu, Shih-Chieh; Hu, Diedi; Hu, Xueye; Huang, Yanping; Hubacek, Zdenek; Hubaut, Fabrice; Huegging, Fabian; Huffman, Todd Brian; Hughes, Emlyn; Hughes, Gareth; Huhtinen, Mika; Hülsing, Tobias Alexander; Hurwitz, Martina; Huseynov, Nazim; Huston, Joey; Huth, John; Iacobucci, Giuseppe; Iakovidis, Georgios; Ibragimov, Iskander; Iconomidou-Fayard, Lydia; Ideal, Emma; Iengo, Paolo; Igonkina, Olga; Iizawa, Tomoya; Ikegami, Yoichi; Ikematsu, Katsumasa; Ikeno, Masahiro; Iliadis, Dimitrios; Ilic, Nikolina; Inamaru, Yuki; Ince, Tayfun; Ioannou, Pavlos; Iodice, Mauro; Iordanidou, Kalliopi; Ippolito, Valerio; Irles Quiles, Adrian; Isaksson, Charlie; Ishino, Masaya; Ishitsuka, Masaki; Ishmukhametov, Renat; Issever, Cigdem; Istin, Serhat; Iturbe Ponce, Julia Mariana; Ivashin, Anton; Iwanski, Wieslaw; Iwasaki, Hiroyuki; Izen, Joseph; Izzo, Vincenzo; Jackson, Brett; Jackson, John; Jackson, Matthew; Jackson, Paul; Jaekel, Martin; Jain, Vivek; Jakobs, Karl; Jakobsen, Sune; Jakoubek, Tomas; Jakubek, Jan; Jamin, David Olivier; Jana, Dilip; Jansen, Eric; Jansen, Hendrik; Janssen, Jens; Janus, Michel; Jarlskog, Göran; Javůrek, Tomáš; Jeanty, Laura; Jeng, Geng-yuan; Jennens, David; Jenni, Peter; Jentzsch, Jennifer; Jeske, Carl; Jézéquel, Stéphane; Ji, Haoshuang; Ji, Weina; Jia, Jiangyong; Jiang, Yi; Jimenez Belenguer, Marcos; Jin, Shan; Jinaru, Adam; Jinnouchi, Osamu; Joergensen, Morten Dam; Johansson, Erik; Johansson, Per; Johns, Kenneth; Jon-And, Kerstin; Jones, Graham; Jones, Roger; Jones, Tim; Jongmanns, Jan; Jorge, Pedro; Joshi, Kiran Daniel; Jovicevic, Jelena; Ju, Xiangyang; Jung, Christian; Jungst, Ralph Markus; Jussel, Patrick; Juste Rozas, Aurelio; Kaci, Mohammed; Kaczmarska, Anna; Kado, Marumi; Kagan, Harris; Kagan, Michael; Kajomovitz, Enrique; Kama, Sami; Kanaya, Naoko; Kaneda, Michiru; Kaneti, Steven; Kanno, Takayuki; Kantserov, Vadim; Kanzaki, Junichi; Kaplan, Benjamin; Kapliy, Anton; Kar, Deepak; Karakostas, Konstantinos; Karastathis, Nikolaos; Karnevskiy, Mikhail; Karpov, Sergey; Karthik, Krishnaiyengar; Kartvelishvili, Vakhtang; Karyukhin, Andrey; Kashif, Lashkar; Kasieczka, Gregor; Kass, Richard; Kastanas, Alex; Kataoka, Yousuke; Katre, Akshay; Katzy, Judith; Kaushik, Venkatesh; Kawagoe, Kiyotomo; Kawamoto, Tatsuo; Kawamura, Gen; Kazama, Shingo; Kazanin, Vassili; Kazarinov, Makhail; Keeler, Richard; Kehoe, Robert; Keil, Markus; Keller, John; Keoshkerian, Houry; Kepka, Oldrich; Kerševan, Borut Paul; Kersten, Susanne; Kessoku, Kohei; Keung, Justin; Khalil-zada, Farkhad; Khandanyan, Hovhannes; Khanov, Alexander; Khodinov, Alexander; Khomich, Andrei; Khoo, Teng Jian; Khoriauli, Gia; Khoroshilov, Andrey; Khovanskiy, Valery; Khramov, Evgeniy; Khubua, Jemal; Kim, Hee Yeun; Kim, Hyeon Jin; Kim, Shinhong; Kimura, Naoki; Kind, Oliver; King, Barry; King, Matthew; King, Robert Steven Beaufoy; King, Samuel Burton; Kirk, Julie; Kiryunin, Andrey; Kishimoto, Tomoe; Kisielewska, Danuta; Kiss, Florian; Kitamura, Takumi; Kittelmann, Thomas; Kiuchi, Kenji; Kladiva, Eduard; Klein, Max; Klein, Uta; Kleinknecht, Konrad; Klimek, Pawel; Klimentov, Alexei; Klingenberg, Reiner; Klinger, Joel Alexander; Klinkby, Esben; Klioutchnikova, Tatiana; Klok, Peter; Kluge, Eike-Erik; Kluit, Peter; Kluth, Stefan; Kneringer, Emmerich; Knoops, Edith; Knue, Andrea; Kobayashi, Tomio; Kobel, Michael; Kocian, Martin; Kodys, Peter; Koevesarki, Peter; Koffas, Thomas; Koffeman, Els; Kogan, Lucy Anne; Kohlmann, Simon; Kohout, Zdenek; Kohriki, Takashi; Koi, Tatsumi; Kolanoski, Hermann; Koletsou, Iro; Koll, James; Komar, Aston; Komori, Yuto; Kondo, Takahiko; Köneke, Karsten; König, Adriaan; König, Sebastian; Kono, Takanori; Konoplich, Rostislav; Konstantinidis, Nikolaos; Kopeliansky, Revital; Koperny, Stefan; Köpke, Lutz; Kopp, Anna Katharina; Korcyl, Krzysztof; Kordas, Kostantinos; Korn, Andreas; Korol, Aleksandr; Korolkov, Ilya; Korolkova, Elena; Korotkov, Vladislav; Kortner, Oliver; Kortner, Sandra; Kostyukhin, Vadim; Kotov, Vladislav; Kotwal, Ashutosh; Kourkoumelis, Christine; Kouskoura, Vasiliki; Koutsman, Alex; Kowalewski, Robert Victor; Kowalski, Tadeusz; Kozanecki, Witold; Kozhin, Anatoly; Kral, Vlastimil; Kramarenko, Viktor; Kramberger, Gregor; Krasnopevtsev, Dimitriy; Krasny, Mieczyslaw Witold; Krasznahorkay, Attila; Kraus, Jana; Kravchenko, Anton; Kreiss, Sven; Kretz, Moritz; Kretzschmar, Jan; Kreutzfeldt, Kristof; Krieger, Peter; Kroeninger, Kevin; Kroha, Hubert; Kroll, Joe; Kroseberg, Juergen; Krstic, Jelena; Kruchonak, Uladzimir; Krüger, Hans; Kruker, Tobias; Krumnack, Nils; Krumshteyn, Zinovii; Kruse, Amanda; Kruse, Mark; Kruskal, Michael; Kubota, Takashi; Kuday, Sinan; Kuehn, Susanne; Kugel, Andreas; Kuhl, Andrew; Kuhl, Thorsten; Kukhtin, Victor; Kulchitsky, Yuri; Kuleshov, Sergey; Kuna, Marine; Kunkle, Joshua; Kupco, Alexander; Kurashige, Hisaya; Kurochkin, Yurii; Kurumida, Rie; Kus, Vlastimil; Kuwertz, Emma Sian; Kuze, Masahiro; Kvita, Jiri; La Rosa, Alessandro; La Rotonda, Laura; Labarga, Luis; Lacasta, Carlos; Lacava, Francesco; Lacey, James; Lacker, Heiko; Lacour, Didier; Lacuesta, Vicente Ramón; Ladygin, Evgueni; Lafaye, Remi; Laforge, Bertrand; Lagouri, Theodota; Lai, Stanley; Laier, Heiko; Lambourne, Luke; Lammers, Sabine; Lampen, Caleb; Lampl, Walter; Lançon, Eric; Landgraf, Ulrich; Landon, Murrough; Lang, Valerie Susanne; Lange, Clemens; Lankford, Andrew; Lanni, Francesco; Lantzsch, Kerstin; Laplace, Sandrine; Lapoire, Cecile; Laporte, Jean-Francois; Lari, Tommaso; Lassnig, Mario; Laurelli, Paolo; Lavorini, Vincenzo; Lavrijsen, Wim; Law, Alexander; Laycock, Paul; Le, Bao Tran; Le Dortz, Olivier; Le Guirriec, Emmanuel; Le Menedeu, Eve; LeCompte, Thomas; Ledroit-Guillon, Fabienne Agnes Marie; Lee, Claire Alexandra; Lee, Hurng-Chun; Lee, Jason; Lee, Shih-Chang; Lee, Lawrence; Lefebvre, Guillaume; Lefebvre, Michel; Legger, Federica; Leggett, Charles; Lehan, Allan; Lehmacher, Marc; Lehmann Miotto, Giovanna; Lei, Xiaowen; Leister, Andrew Gerard; Leite, Marco Aurelio Lisboa; Leitner, Rupert; Lellouch, Daniel; Lemmer, Boris; Leney, Katharine; Lenz, Tatjana; Lenzen, Georg; Lenzi, Bruno; Leone, Robert; Leonhardt, Kathrin; Leontsinis, Stefanos; Leroy, Claude; Lester, Christopher; Lester, Christopher Michael; Levêque, Jessica; Levin, Daniel; Levinson, Lorne; Levy, Mark; Lewis, Adrian; Lewis, George; Leyko, Agnieszka; Leyton, Michael; Li, Bing; Li, Bo; Li, Haifeng; Li, Ho Ling; Li, Shu; Li, Xuefei; Li, Yichen; Liang, Zhijun; Liao, Hongbo; Liberti, Barbara; Lichard, Peter; Lie, Ki; Liebal, Jessica; Liebig, Wolfgang; Limbach, Christian; Limosani, Antonio; Limper, Maaike; Lin, Simon; Linde, Frank; Lindquist, Brian Edward; Linnemann, James; Lipeles, Elliot; Lipniacka, Anna; Lisovyi, Mykhailo; Liss, Tony; Lissauer, David; Lister, Alison; Litke, Alan; Liu, Bo; Liu, Dong; Liu, Jianbei; Liu, Kun; Liu, Lulu; Liu, Miaoyuan; Liu, Minghui; Liu, Yanwen; Livan, Michele; Livermore, Sarah; Lleres, Annick; Llorente Merino, Javier; Lloyd, Stephen; Lo Sterzo, Francesco; Lobodzinska, Ewelina; Loch, Peter; Lockman, William; Loddenkoetter, Thomas; Loebinger, Fred; Loevschall-Jensen, Ask Emil; Loginov, Andrey; Loh, Chang Wei; Lohse, Thomas; Lohwasser, Kristin; Lokajicek, Milos; Lombardo, Vincenzo Paolo; Long, Jonathan; Long, Robin Eamonn; Lopes, Lourenco; Lopez Mateos, David; Lopez Paredes, Brais; Lorenz, Jeanette; Lorenzo Martinez, Narei; Losada, Marta; Loscutoff, Peter; Losty, Michael; Lou, XinChou; Lounis, Abdenour; Love, Jeremy; Love, Peter; Lowe, Andrew; Lu, Feng; Lubatti, Henry; Luci, Claudio; Lucotte, Arnaud; Luehring, Frederick; Lukas, Wolfgang; Luminari, Lamberto; Lundberg, Olof; Lund-Jensen, Bengt; Lungwitz, Matthias; Lynn, David; Lysak, Roman; Lytken, Else; Ma, Hong; Ma, Lian Liang; Maccarrone, Giovanni; Macchiolo, Anna; Maček, Boštjan; Machado Miguens, Joana; Macina, Daniela; Madaffari, Daniele; Madar, Romain; Maddocks, Harvey Jonathan; Mader, Wolfgang; Madsen, Alexander; Maeno, Mayuko; Maeno, Tadashi; Magradze, Erekle; Mahboubi, Kambiz; Mahlstedt, Joern; Mahmoud, Sara; Maiani, Camilla; Maidantchik, Carmen; Maio, Amélia; Majewski, Stephanie; Makida, Yasuhiro; Makovec, Nikola; Mal, Prolay; Malaescu, Bogdan; Malecki, Pawel; Maleev, Victor; Malek, Fairouz; Mallik, Usha; Malon, David; Malone, Caitlin; Maltezos, Stavros; Malyshev, Vladimir; Malyukov, Sergei; Mamuzic, Judita; Mandelli, Beatrice; Mandelli, Luciano; Mandić, Igor; Mandrysch, Rocco; Maneira, José; Manfredini, Alessandro; Manhaes de Andrade Filho, Luciano; Manjarres Ramos, Joany Andreina; Mann, Alexander; Manning, Peter; Manousakis-Katsikakis, Arkadios; Mansoulie, Bruno; Mantifel, Rodger; Mapelli, Livio; March, Luis; Marchand, Jean-Francois; Marchese, Fabrizio; Marchiori, Giovanni; Marcisovsky, Michal; Marino, Christopher; Marques, Carlos; Marroquim, Fernando; Marsden, Stephen Philip; Marshall, Zach; Marti, Lukas Fritz; Marti-Garcia, Salvador; Martin, Brian; Martin, Brian Thomas; Martin, Tim; Martin, Victoria Jane; Martin dit Latour, Bertrand; Martinez, Homero; Martinez, Mario; Martin-Haugh, Stewart; Martyniuk, Alex; Marx, Marilyn; Marzano, Francesco; Marzin, Antoine; Masetti, Lucia; Mashimo, Tetsuro; Mashinistov, Ruslan; Masik, Jiri; Maslennikov, Alexey; Massa, Ignazio; Massol, Nicolas; Mastrandrea, Paolo; Mastroberardino, Anna; Masubuchi, Tatsuya; Matsunaga, Hiroyuki; Matsushita, Takashi; Mättig, Peter; Mättig, Stefan; Mattmann, Johannes; Maurer, Julien; Maxfield, Stephen; Maximov, Dmitriy; Mazini, Rachid; Mazzaferro, Luca; Mc Goldrick, Garrin; Mc Kee, Shawn Patrick; McCarn, Allison; McCarthy, Robert; McCarthy, Tom; McCubbin, Norman; McFarlane, Kenneth; Mcfayden, Josh; Mchedlidze, Gvantsa; Mclaughlan, Tom; McMahon, Steve; McPherson, Robert; Meade, Andrew; Mechnich, Joerg; Medinnis, Michael; Meehan, Samuel; Meera-Lebbai, Razzak; Mehlhase, Sascha; Mehta, Andrew; Meier, Karlheinz; Meineck, Christian; Meirose, Bernhard; Melachrinos, Constantinos; Mellado Garcia, Bruce Rafael; Meloni, Federico; Mendoza Navas, Luis; Mengarelli, Alberto; Menke, Sven; Meoni, Evelin; Mercurio, Kevin Michael; Mergelmeyer, Sebastian; Meric, Nicolas; Mermod, Philippe; Merola, Leonardo; Meroni, Chiara; Merritt, Frank; Merritt, Hayes; Messina, Andrea; Metcalfe, Jessica; Mete, Alaettin Serhan; Meyer, Carsten; Meyer, Christopher; Meyer, Jean-Pierre; Meyer, Jochen; Middleton, Robin; Migas, Sylwia; Mijović, Liza; Mikenberg, Giora; Mikestikova, Marcela; Mikuž, Marko; Miller, David; Mills, Corrinne; Milov, Alexander; Milstead, David; Milstein, Dmitry; Minaenko, Andrey; Miñano Moya, Mercedes; Minashvili, Irakli; Mincer, Allen; Mindur, Bartosz; Mineev, Mikhail; Ming, Yao; Mir, Lluisa-Maria; Mirabelli, Giovanni; Mitani, Takashi; Mitrevski, Jovan; Mitsou, Vasiliki A; Mitsui, Shingo; Miucci, Antonio; Miyagawa, Paul; Mjörnmark, Jan-Ulf; Moa, Torbjoern; Mochizuki, Kazuya; Moeller, Victoria; Mohapatra, Soumya; Mohr, Wolfgang; Molander, Simon; Moles-Valls, Regina; Mönig, Klaus; Monini, Caterina; Monk, James; Monnier, Emmanuel; Montejo Berlingen, Javier; Monticelli, Fernando; Monzani, Simone; Moore, Roger; Mora Herrera, Clemencia; Moraes, Arthur; Morange, Nicolas; Morel, Julien; Moreno, Deywis; Moreno Llácer, María; Morettini, Paolo; Morgenstern, Marcus; Morii, Masahiro; Moritz, Sebastian; Morley, Anthony Keith; Mornacchi, Giuseppe; Morris, John; Morvaj, Ljiljana; Moser, Hans-Guenther; Mosidze, Maia; Moss, Josh; Mount, Richard; Mountricha, Eleni; Mouraviev, Sergei; Moyse, Edward; Muanza, Steve; Mudd, Richard; Mueller, Felix; Mueller, James; Mueller, Klemens; Mueller, Thibaut; Mueller, Timo; Muenstermann, Daniel; Munwes, Yonathan; Murillo Quijada, Javier Alberto; Murray, Bill; Musto, Elisa; Myagkov, Alexey; Myska, Miroslav; Nackenhorst, Olaf; Nadal, Jordi; Nagai, Koichi; Nagai, Ryo; Nagai, Yoshikazu; Nagano, Kunihiro; Nagarkar, Advait; Nagasaka, Yasushi; Nagel, Martin; Nairz, Armin Michael; Nakahama, Yu; Nakamura, Koji; Nakamura, Tomoaki; Nakano, Itsuo; Namasivayam, Harisankar; Nanava, Gizo; Narayan, Rohin; Nattermann, Till; Naumann, Thomas; Navarro, Gabriela; Nayyar, Ruchika; Neal, Homer; Nechaeva, Polina; Neep, Thomas James; Negri, Andrea; Negri, Guido; Negrini, Matteo; Nektarijevic, Snezana; Nelson, Andrew; Nelson, Timothy Knight; Nemecek, Stanislav; Nemethy, Peter; Nepomuceno, Andre Asevedo; Nessi, Marzio; Neubauer, Mark; Neumann, Manuel; Neves, Ricardo; Nevski, Pavel; Newman, Paul; Nguyen, Duong Hai; Nickerson, Richard; Nicolaidou, Rosy; Nicquevert, Bertrand; Nielsen, Jason; Nikiforou, Nikiforos; Nikiforov, Andriy; Nikolaenko, Vladimir; Nikolic-Audit, Irena; Nikolics, Katalin; Nikolopoulos, Konstantinos; Nilsson, Paul; Ninomiya, Yoichi; Nisati, Aleandro; Nisius, Richard; Nobe, Takuya; Nodulman, Lawrence; Nomachi, Masaharu; Nomidis, Ioannis; Norberg, Scarlet; Nordberg, Markus; Nowak, Sebastian; Nozaki, Mitsuaki; Nozka, Libor; Ntekas, Konstantinos; Nunes Hanninger, Guilherme; Nunnemann, Thomas; Nurse, Emily; Nuti, Francesco; O'Brien, Brendan Joseph; O'grady, Fionnbarr; O'Neil, Dugan; O'Shea, Val; Oakham, Gerald; Oberlack, Horst; Obermann, Theresa; Ocariz, Jose; Ochi, Atsuhiko; Ochoa, Ines; Oda, Susumu; Odaka, Shigeru; Ogren, Harold; Oh, Alexander; Oh, Seog; Ohm, Christian; Ohman, Henrik; Ohshima, Takayoshi; Okamura, Wataru; Okawa, Hideki; Okumura, Yasuyuki; Okuyama, Toyonobu; Olariu, Albert; Olchevski, Alexander; Olivares Pino, Sebastian Andres; Oliveira Damazio, Denis; Oliver Garcia, Elena; Olivito, Dominick; Olszewski, Andrzej; Olszowska, Jolanta; Onofre, António; Onyisi, Peter; Oram, Christopher; Oreglia, Mark; Oren, Yona; Orestano, Domizia; Orlando, Nicola; Oropeza Barrera, Cristina; Orr, Robert; Osculati, Bianca; Ospanov, Rustem; Otero y Garzon, Gustavo; Otono, Hidetoshi; Ouchrif, Mohamed; Ouellette, Eric; Ould-Saada, Farid; Ouraou, Ahmimed; Oussoren, Koen Pieter; Ouyang, Qun; Ovcharova, Ana; Owen, Mark; Ozcan, Veysi Erkcan; Ozturk, Nurcan; Pachal, Katherine; Pacheco Pages, Andres; Padilla Aranda, Cristobal; Pagáčová, Martina; Pagan Griso, Simone; Paganis, Efstathios; Pahl, Christoph; Paige, Frank; Pais, Preema; Pajchel, Katarina; Palacino, Gabriel; Palestini, Sandro; Pallin, Dominique; Palma, Alberto; Palmer, Jody; Pan, Yibin; Panagiotopoulou, Evgenia; Panduro Vazquez, William; Pani, Priscilla; Panikashvili, Natalia; Panitkin, Sergey; Pantea, Dan; Paolozzi, Lorenzo; Papadopoulou, Theodora; Papageorgiou, Konstantinos; Paramonov, Alexander; Paredes Hernandez, Daniela; Parker, Michael Andrew; Parodi, Fabrizio; Parsons, John; Parzefall, Ulrich; Pasqualucci, Enrico; Passaggio, Stefano; Passeri, Antonio; Pastore, Fernanda; Pastore, Francesca; Pásztor, Gabriella; Pataraia, Sophio; Patel, Nikhul; Pater, Joleen; Patricelli, Sergio; Pauly, Thilo; Pearce, James; Pedersen, Maiken; Pedraza Lopez, Sebastian; Pedro, Rute; Peleganchuk, Sergey; Pelikan, Daniel; Peng, Haiping; Penning, Bjoern; Penwell, John; Perepelitsa, Dennis; Perez Codina, Estel; Pérez García-Estañ, María Teresa; Perez Reale, Valeria; Perini, Laura; Pernegger, Heinz; Perrino, Roberto; Peschke, Richard; Peshekhonov, Vladimir; Peters, Krisztian; Peters, Yvonne; Petersen, Brian; Petersen, Jorgen; Petersen, Troels; Petit, Elisabeth; Petridis, Andreas; Petridou, Chariclia; Petrolo, Emilio; Petrucci, Fabrizio; Petteni, Michele; Pettersson, Nora Emilia; Pezoa, Raquel; Phillips, Peter William; Piacquadio, Giacinto; Pianori, Elisabetta; Picazio, Attilio; Piccaro, Elisa; Piccinini, Maurizio; Piec, Sebastian Marcin; Piegaia, Ricardo; Pignotti, David; Pilcher, James; Pilkington, Andrew; Pina, João Antonio; Pinamonti, Michele; Pinder, Alex; Pinfold, James; Pingel, Almut; Pinto, Belmiro; Pires, Sylvestre; Pizio, Caterina; Pleier, Marc-Andre; Pleskot, Vojtech; Plotnikova, Elena; Plucinski, Pawel; Poddar, Sahill; Podlyski, Fabrice; Poettgen, Ruth; Poggioli, Luc; Pohl, David-leon; Pohl, Martin; Polesello, Giacomo; Policicchio, Antonio; Polifka, Richard; Polini, Alessandro; Pollard, Christopher Samuel; Polychronakos, Venetios; Pommès, Kathy; Pontecorvo, Ludovico; Pope, Bernard; Popeneciu, Gabriel Alexandru; Popovic, Dragan; Poppleton, Alan; Portell Bueso, Xavier; Pospelov, Guennady; Pospisil, Stanislav; Potamianos, Karolos; Potrap, Igor; Potter, Christina; Potter, Christopher; Poulard, Gilbert; Poveda, Joaquin; Pozdnyakov, Valery; Prabhu, Robindra; Pralavorio, Pascal; Pranko, Aliaksandr; Prasad, Srivas; Pravahan, Rishiraj; Prell, Soeren; Price, Darren; Price, Joe; Price, Lawrence; Prieur, Damien; Primavera, Margherita; Proissl, Manuel; Prokofiev, Kirill; Prokoshin, Fedor; Protopapadaki, Eftychia-sofia; Protopopescu, Serban; Proudfoot, James; Przybycien, Mariusz; Przysiezniak, Helenka; Ptacek, Elizabeth; Pueschel, Elisa; Puldon, David; Purohit, Milind; Puzo, Patrick; Pylypchenko, Yuriy; Qian, Jianming; Qin, Gang; Quadt, Arnulf; Quarrie, David; Quayle, William; Quilty, Donnchadha; Qureshi, Anum; Radeka, Veljko; Radescu, Voica; Radhakrishnan, Sooraj Krishnan; Radloff, Peter; Rados, Pere; Ragusa, Francesco; Rahal, Ghita; Rajagopalan, Srinivasan; Rammensee, Michael; Rammes, Marcus; Randle-Conde, Aidan Sean; Rangel-Smith, Camila; Rao, Kanury; Rauscher, Felix; Rave, Tobias Christian; Ravenscroft, Thomas; Raymond, Michel; Read, Alexander Lincoln; Rebuzzi, Daniela; Redelbach, Andreas; Redlinger, George; Reece, Ryan; Reeves, Kendall; Rehnisch, Laura; Reinsch, Andreas; Reisin, Hernan; Relich, Matthew; Rembser, Christoph; Ren, Zhongliang; Renaud, Adrien; Rescigno, Marco; Resconi, Silvia; Rezanova, Olga; Reznicek, Pavel; Rezvani, Reyhaneh; Richter, Robert; Ridel, Melissa; Rieck, Patrick; Rijssenbeek, Michael; Rimoldi, Adele; Rinaldi, Lorenzo; Ritsch, Elmar; Riu, Imma; Rizatdinova, Flera; Rizvi, Eram; Robertson, Steven; Robichaud-Veronneau, Andree; Robinson, Dave; Robinson, James; Robson, Aidan; Roda, Chiara; Rodrigues, Luis; Roe, Shaun; Røhne, Ole; Rolli, Simona; Romaniouk, Anatoli; Romano, Marino; Romeo, Gaston; Romero Adam, Elena; Rompotis, Nikolaos; Roos, Lydia; Ros, Eduardo; Rosati, Stefano; Rosbach, Kilian; Rose, Anthony; Rose, Matthew; Rosendahl, Peter Lundgaard; Rosenthal, Oliver; Rossetti, Valerio; Rossi, Elvira; Rossi, Leonardo Paolo; Rosten, Rachel; Rotaru, Marina; Roth, Itamar; Rothberg, Joseph; Rousseau, David; Royon, Christophe; Rozanov, Alexandre; Rozen, Yoram; Ruan, Xifeng; Rubbo, Francesco; Rubinskiy, Igor; Rud, Viacheslav; Rudolph, Christian; Rudolph, Matthew Scott; Rühr, Frederik; Ruiz-Martinez, Aranzazu; Rurikova, Zuzana; Rusakovich, Nikolai; Ruschke, Alexander; Rutherfoord, John; Ruthmann, Nils; Ryabov, Yury; Rybar, Martin; Rybkin, Grigori; Ryder, Nick; Saavedra, Aldo; Sacerdoti, Sabrina; Saddique, Asif; Sadeh, Iftach; Sadrozinski, Hartmut; Sadykov, Renat; Safai Tehrani, Francesco; Sakamoto, Hiroshi; Sakurai, Yuki; Salamanna, Giuseppe; Salamon, Andrea; Saleem, Muhammad; Salek, David; Sales De Bruin, Pedro Henrique; Salihagic, Denis; Salnikov, Andrei; Salt, José; Salvachua Ferrando, Belén; Salvatore, Daniela; Salvatore, Pasquale Fabrizio; Salvucci, Antonio; Salzburger, Andreas; Sampsonidis, Dimitrios; Sanchez, Arturo; Sánchez, Javier; 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Dean; Scharf, Veit; Schegelsky, Valery; Scheirich, Daniel; Schernau, Michael; Scherzer, Max; Schiavi, Carlo; Schieck, Jochen; Schillo, Christian; Schioppa, Marco; Schlenker, Stefan; Schmidt, Evelyn; Schmieden, Kristof; Schmitt, Christian; Schmitt, Christopher; Schmitt, Sebastian; Schneider, Basil; Schnellbach, Yan Jie; Schnoor, Ulrike; Schoeffel, Laurent; Schoening, Andre; Schoenrock, Bradley Daniel; Schorlemmer, Andre Lukas; Schott, Matthias; Schouten, Doug; Schovancova, Jaroslava; Schramm, Steven; Schreyer, Manuel; Schroeder, Christian; Schuh, Natascha; Schultens, Martin Johannes; Schultz-Coulon, Hans-Christian; Schulz, Holger; Schumacher, Markus; Schumm, Bruce; Schune, Philippe; Schwartzman, Ariel; Schwegler, Philipp; Schwemling, Philippe; Schwienhorst, Reinhard; Schwindling, Jerome; Schwindt, Thomas; Schwoerer, Maud; Sciacca, Gianfranco; Scifo, Estelle; Sciolla, Gabriella; Scott, Bill; Scuri, Fabrizio; Scutti, Federico; Searcy, Jacob; Sedov, George; Sedykh, Evgeny; Seidel, Sally; Seiden, Abraham; Seifert, Frank; Seixas, José; Sekhniaidze, Givi; Sekula, Stephen; Selbach, Karoline Elfriede; Seliverstov, Dmitry; Sellers, Graham; Semprini-Cesari, Nicola; Serfon, Cedric; Serin, Laurent; Serkin, Leonid; Serre, Thomas; Seuster, Rolf; Severini, Horst; Sforza, Federico; Sfyrla, Anna; Shabalina, Elizaveta; Shamim, Mansoora; Shan, Lianyou; Shank, James; Shao, Qi Tao; Shapiro, Marjorie; Shatalov, Pavel; Shaw, Kate; Sherwood, Peter; Shimizu, Shima; Shimmin, Chase Owen; Shimojima, Makoto; Shiyakova, Mariya; Shmeleva, Alevtina; Shochet, Mel; Short, Daniel; Shrestha, Suyog; Shulga, Evgeny; Shupe, Michael; Shushkevich, Stanislav; Sicho, Petr; Sidorov, Dmitri; Sidoti, Antonio; Siegert, Frank; Sijacki, Djordje; Silbert, Ohad; Silva, José; Silver, Yiftah; Silverstein, Daniel; Silverstein, Samuel; Simak, Vladislav; Simard, Olivier; Simic, Ljiljana; Simion, Stefan; Simioni, Eduard; Simmons, Brinick; Simoniello, Rosa; Simonyan, Margar; Sinervo, Pekka; Sinev, Nikolai; Sipica, Valentin; Siragusa, Giovanni; 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Terada, Susumu; Terashi, Koji; Terron, Juan; Terzo, Stefano; Testa, Marianna; Teuscher, Richard; Therhaag, Jan; Theveneaux-Pelzer, Timothée; Thoma, Sascha; Thomas, Juergen; Thomas-Wilsker, Joshuha; Thompson, Emily; Thompson, Paul; Thompson, Peter; Thompson, Stan; Thomsen, Lotte Ansgaard; Thomson, Evelyn; Thomson, Mark; Thong, Wai Meng; Thun, Rudolf; Tian, Feng; Tibbetts, Mark James; Tikhomirov, Vladimir; Tikhonov, Yury; Timoshenko, Sergey; Tiouchichine, Elodie; Tipton, Paul; Tisserant, Sylvain; Todorov, Theodore; Todorova-Nova, Sharka; Toggerson, Brokk; Tojo, Junji; Tokár, Stanislav; Tokushuku, Katsuo; Tollefson, Kirsten; Tomlinson, Lee; Tomoto, Makoto; Tompkins, Lauren; Toms, Konstantin; Topilin, Nikolai; Torrence, Eric; Torres, Heberth; Torró Pastor, Emma; Toth, Jozsef; Touchard, Francois; Tovey, Daniel; Tran, Huong Lan; Trefzger, Thomas; Tremblet, Louis; Tricoli, Alessandro; Trigger, Isabel Marian; Trincaz-Duvoid, Sophie; Tripiana, Martin; Triplett, Nathan; Trischuk, William; Trocmé, Benjamin; 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Zeman, Martin; Zemla, Andrzej; Zengel, Keith; Zenin, Oleg; Ženiš, Tibor; Zerwas, Dirk; Zevi della Porta, Giovanni; Zhang, Dongliang; Zhang, Fangzhou; Zhang, Huaqiao; Zhang, Jinlong; Zhang, Lei; Zhang, Xueyao; Zhang, Zhiqing; Zhao, Zhengguo; Zhemchugov, Alexey; Zhong, Jiahang; Zhou, Bing; Zhou, Lei; Zhou, Ning; Zhu, Cheng Guang; Zhu, Hongbo; Zhu, Junjie; Zhu, Yingchun; Zhuang, Xuai; Zibell, Andre; Zieminska, Daria; Zimine, Nikolai; Zimmermann, Christoph; Zimmermann, Robert; Zimmermann, Simone; Zimmermann, Stephanie; Zinonos, Zinonas; Ziolkowski, Michael; Zitoun, Robert; Zobernig, Georg; Zoccoli, Antonio; zur Nedden, Martin; Zurzolo, Giovanni; Zutshi, Vishnu; Zwalinski, Lukasz

2014-08-12

Distributions sensitive to the underlying event in QCD jet events have been measured with the ATLAS detector at the LHC, based on 37/pb of proton-proton collision data collected at a centre-of-mass energy of 7TeV. Charged-particle mean $p_T$ and densities of all-particle $E_T$ and charged-particle multiplicity and $p_T$ have been measured in regions azimuthally transverse to the hardest jet in each event. These are presented both as one-dimensional distributions and with their mean values as functions of the leading-jet transverse momentum from 20 GeV to 800 GeV. The correlation of charged-particle mean $p_T$ with charged-particle multiplicity is also studied, and the $E_T$ densities include the forward rapidity region; these features provide extra data constraints for Monte Carlo modelling of colour reconnection and beam-remnant effects respectively. For the first time, underlying event observables have been computed separately for inclusive jet and exclusive dijet event selections, allowing more detailed st...

Foundations for Streaming Model Transformations by Complex Event Processing.

Science.gov (United States)

Dávid, István; Ráth, István; Varró, Dániel

2018-01-01

Streaming model transformations represent a novel class of transformations to manipulate models whose elements are continuously produced or modified in high volume and with rapid rate of change. Executing streaming transformations requires efficient techniques to recognize activated transformation rules over a live model and a potentially infinite stream of events. In this paper, we propose foundations of streaming model transformations by innovatively integrating incremental model query, complex event processing (CEP) and reactive (event-driven) transformation techniques. Complex event processing allows to identify relevant patterns and sequences of events over an event stream. Our approach enables event streams to include model change events which are automatically and continuously populated by incremental model queries. Furthermore, a reactive rule engine carries out transformations on identified complex event patterns. We provide an integrated domain-specific language with precise semantics for capturing complex event patterns and streaming transformations together with an execution engine, all of which is now part of the Viatra reactive transformation framework. We demonstrate the feasibility of our approach with two case studies: one in an advanced model engineering workflow; and one in the context of on-the-fly gesture recognition.

Unitarity corrections to short-range order long-range rapidity correlations

CERN Document Server

Capella, A

1978-01-01

Although the effective hadronic forces have short range in rapidity space, one nevertheless expects long-range dynamical correlations induced by unitarity constraints. This paper contains a thorough discussion of long-range rapidity correlations in high-multiplicity events. In particular, the authors analyze in detail the forward- backward multiplicity correlations, measured recently in the whole CERN ISR energy range. They find from these data that the normalized variance of the number n of exchanged cut Pomerons, ((n/(n)-1)/sup 2/) , is most probably in the range 0.32 to 0.36. They show that such a number is obtained from Reggeon theory in the eikonal approximation. The authors also predict a very specific violation of local compensation of charge in multiparticle events: The violation should appear in the fourth-order zone correlation function and is absent in the second-order correlation function, the only one measured until now. (48 refs).

Intensification of Wild Silkworm Attacus atlas Rearing (Lepidoptera: Saturniidae

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B. K. Desmawita

2013-12-01

Full Text Available Study on intensification program through reproduction and feeding management was conducted for six months to evaluate the growth and reproductive performance of wild silkworm, Attacus atlas. The experiment was divided into two phases: 1 the first phase was conducted on mating management, by applying different times of mating duration of 3, 6, 12, and 24 h as treatments to assess eggs production. In this phase, a completely randomized design was used, with 4 treatments and 5 replications; 2 the second phase was on feeding management, a completely randomized design method (2 x 2 was used, including feed (guava and walnut leaves as first factor, and the second factor was feeding times (3 and 4 times/day with 5 replications. The results obtained from the first experiment showed that different duration of mating significantly (P<0.05 affected the number of eggs produced. Based on time efficiency 6 hours mating duration produced higher egg production (226 egg/cycle, as well as hatchability (95% than those of other mating duration. In the second experiment, it was found that there was interaction between feed types and feeding frequencies which significantly (P<0.05 affected feed consumption, feed digestibility, body weight gain, diameter of larvae and mortality rate. In conclusion, the optimum and efficient duration sugested for mating is six hours resulting high egg production. The walnut leaves feed has better effect on the first and second instar of larvae, while the guava leaves affect the following instars. In terms of production, four times of feeding frequency per day has higher productivity and is recommended in the cultivation management of A. atlas.

Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production.

Science.gov (United States)

Tapia, Felipe; Vázquez-Ramírez, Daniel; Genzel, Yvonne; Reichl, Udo

2016-03-01

With an increasing demand for efficacious, safe, and affordable vaccines for human and animal use, process intensification in cell culture-based viral vaccine production demands advanced process strategies to overcome the limitations of conventional batch cultivations. However, the use of fed-batch, perfusion, or continuous modes to drive processes at high cell density (HCD) and overextended operating times has so far been little explored in large-scale viral vaccine manufacturing. Also, possible reductions in cell-specific virus yields for HCD cultivations have been reported frequently. Taking into account that vaccine production is one of the most heavily regulated industries in the pharmaceutical sector with tough margins to meet, it is understandable that process intensification is being considered by both academia and industry as a next step toward more efficient viral vaccine production processes only recently. Compared to conventional batch processes, fed-batch and perfusion strategies could result in ten to a hundred times higher product yields. Both cultivation strategies can be implemented to achieve cell concentrations exceeding 10(7) cells/mL or even 10(8) cells/mL, while keeping low levels of metabolites that potentially inhibit cell growth and virus replication. The trend towards HCD processes is supported by development of GMP-compliant cultivation platforms, i.e., acoustic settlers, hollow fiber bioreactors, and hollow fiber-based perfusion systems including tangential flow filtration (TFF) or alternating tangential flow (ATF) technologies. In this review, these process modes are discussed in detail and compared with conventional batch processes based on productivity indicators such as space-time yield, cell concentration, and product titers. In addition, options for the production of viral vaccines in continuous multi-stage bioreactors such as two- and three-stage systems are addressed. While such systems have shown similar virus titers compared to

Bridging the gap between event-by-event fluctuation measurements and theory predictions in relativistic nuclear collisions

Energy Technology Data Exchange (ETDEWEB)

Braun-Munzinger, P., E-mail: p.braun-munzinger@gsi.de [Extreme Matter Institute EMMI, GSI, Darmstadt (Germany); Physikalisches Institut, Universität Heidelberg, Heidelberg (Germany); Rustamov, A., E-mail: a.rustamov@cern.ch [Physikalisches Institut, Universität Heidelberg, Heidelberg (Germany); National Nuclear Research Center, Baku (Azerbaijan); Stachel, J., E-mail: stachel@physi.uni-heidelberg.de [Physikalisches Institut, Universität Heidelberg, Heidelberg (Germany)

2017-04-15

We develop methods to deal with non-dynamical contributions to event-by-event fluctuation measurements of net-particle numbers in relativistic nuclear collisions. These contributions arise from impact parameter fluctuations and from the requirement of overall net-baryon number or net-charge conservation and may mask the dynamical fluctuations of interest, such as those due to critical endpoints in the QCD phase diagram. Within a model of independent particle sources we derive formulae for net-particle fluctuations and develop a rigorous approach to take into account contributions from participant fluctuations in realistic experimental environments and at any cumulant order. Interestingly, contributions from participant fluctuations to the second and third cumulants of net-baryon distributions are found to vanish at mid-rapidity for LHC energies while higher cumulants of even order are non-zero even when the net-baryon number at mid-rapidity is zero. At lower beam energies the effect of participant fluctuations increases and induces spurious higher moments. The necessary corrections become large and need to be carefully taken into account before comparison to theory. We also provide a procedure for selecting the optimal phase–space coverage of particles for fluctuation analyses and discuss quantitatively the necessary correction due to global charge conservation.

Record of palaeoenvironmental changes in the Mid-Polish Basin during the Valanginian Event

Science.gov (United States)

Morales, Chloé; Kujau, Ariane; Heimhofer, Ulrich; Mutterlose, Joerg; Spangenberg, Jorge; Adatte, Thierry; Ploch, Isabela; Föllmi, Karl B.

2013-04-01

The Valanginian stage displays the first major perturbation of the carbon cycle of the Cretaceous period. The Valanginian Weissert episode is associated with a positive excursion (CIE) in δ13Ccarb and δ13Corg values, and the occurrence of a crisis in pelagic and neritic carbonate production (Weissert et al., 1998; Erba, 2004, Föllmi et al., 2007). As for Cretaceous oceanic anoxic events (OAEs), the carbon anomaly is explained by the intensification of continental biogeochemical weathering triggering an increase in marine primary productivity and organic-matter preservation. However, to the contrary of OAEs, the organic matter trapped in the Tethyan Ocean during the Valanginian is both marine and continental and the occurrence of a widespread anoxia could not be evidenced (Westermann et al., 2010; Kujau et al., 2012). The resulting marine Corg burial rates were probably not sufficient to explain the shift in δ13C values and an alternative scheme has been proposed by Westermann et al. (2010): the carbonate platform crisis combined with the storage of organic-matter on the continent may be the major triggers of the δ13C positive shift. (Westermann et al., 2010). We present the results of an analysis of the Wawal drilling core (Mid-Polish Trough), which is of particular interest because of its near-coastal setting and its exceptional preservation, demonstrated by the presence of up to 17 wt.% aragonite. The section consists in marine silty to sandy clays deposited on top of a lower Berriasian karstified limestone. It covers the Early and early Late Valanginian, and displays the onset of the positive excursion. The lack of anoxia is evidenced by trace-element and Rock-Eval data. Two intervals of phosphogenesis are emphasised that appear equivalent in time to the condensed horizons of the northern Tethyan region (Helvetic Alps). A rapid climate change toward less humid and seasonally-contrasted conditions that is similar to the northern Tethyan areas is observed

PENDUGAAN NUTRIENT BUDGET TAMBAK INTENSIF UDANG, Litopenaeus vannamei

Directory of Open Access Journals (Sweden)

Rachmansyah Rachmansyah

2016-11-01

Full Text Available Penelitian ini bertujuan untuk mendapatkan nutrient budget tambak intensif udang Litopenaeus vannamei sebagai acuan alokasi input produksi pada tingkat kapasitas asimilasi lingkungan perairan. Pendugaan nutrient budget tambak udang intensif menggunakan pendekatan mass balance, dihitung berdasarkan input nutrien nitrogen - N dan fosfor – P yang berasal dari pakan, benih, pupuk, media probiotik, inflow, dan output nutrien yang ada pada produksi udang, outflow, dan endapan lumpur di dasar tambak. Sampel air, tanah, sedimen, plankton diambil sebelum penebaran dan setiap dua minggu selama pemeliharaan dari tiga petak tambak, masing-masing 5 titik sampel per petak tambak contoh. Analisis nitrogen dan fosfor dilakukan untuk sampel pakan, karkas udang awal dan akhir. Data managemen budi daya meliputi padat penebaran benur 50 ekor m-2, produksi 1.188—1.489 kg/0,25 ha, dan FCR 1,69—2,14; maka total input nutrien tambak udang Litopenaeus vannamei antara 171,9155—179,3778 (176 ± 3,9586 kgN dan 95,2533—99,4180(97,8340 ± 2,3348 kg P. Pakan mendominasi input N sebesar 61,96% ± 0,66%; disusul inflow 30,93% ± 0,70%; pupuk 6,52% ± 0,15%, serta media probiotik dan benur masing-masing <1%. Pola yang sama terjadi pada input phosphorous dengan komposisi 87,75% ± 0,24% dari pakan; 7,73% ± 0,19% pupuk; 4,05% ± 0,25% inflow dan media probiotik < 1%. Total output nitrogen tambak udang vannamei antara 107,1279-110,1438 (108,4957 ± 1,5274 kg N dan 51,6362—63,6576 (56,1292 ± 6,5604 kg P. Komposisi output nitrogen adalah outflow sebanyak 29,82% ± 3,20%; kemudian udang yang dipanen 21,32% ± 1,33%, lumpur atau sludge 10,40% ± 0,81%. Sedangkan komposisi output phosphorous didominasi oleh lumpur 39,03% ± 6,59%; kemudian udang yang dipanen 15,22% ± 0,85% dan outflow 3,09% ± 0,26%. Efisiensi pakan dan air melalui managemen budi daya yang benar menjadi peubah dominan penentu beban limbah tambak udang. This research was aimed to find out nutrient budget

From the mouths of babes: dental caries in infants and children and the intensification of agriculture in mainland Southeast Asia.

Science.gov (United States)

Halcrow, S E; Harris, N J; Tayles, N; Ikehara-Quebral, R; Pietrusewsky, M

2013-03-01

Many bioarchaeological studies have established a link between increased dental caries prevalence and the intensification of agriculture. However, research in Southeast Asia challenges the global application of this theory. Although often overlooked, dental health of infants and children can provide a sensitive source of information concerning health and subsistence change. This article investigates the prevalence and location of caries in the dentition of infants and children (less than 15 years of age) from eight prehistoric mainland Southeast Asian sites collectively spanning the Neolithic to late Iron Age, during which time rice agriculture became an increasingly important subsistence mode. Caries prevalence varied among the sites but there was no correlation with chronological change. The absence of evidence of a decline in dental health over time can be attributed to the relative noncariogenicity of rice and retention of broad-spectrum subsistence strategies. No differences in caries type indicating differences in dental health were found between the sites, apart from the Iron Age site of Muang Sema. There was a higher prevalence of caries in the deciduous dentition than the permanent dentition, likely due to a cariogenic weaning diet and the higher sensitivity of deciduous teeth to decay. The level of caries in the permanent dentition suggests an increased reliance on less cariogenic foods during childhood, including rice. The absence of a temporal decline in dental health of infants and children strengthens the argument that the relationship between caries and agricultural intensification in Southeast Asia was more complex than the general model suggests. Copyright © 2013 Wiley Periodicals, Inc.

Event-by-event fluctuations in mean pT and mean eT in √(sNN)=130 GeV Au+Au collisions

International Nuclear Information System (INIS)

Adcox, K.; El Chenawi, K.; Ghosh, T.K.; Greene, S.V.; Maguire, C.F.; Miller, T.E.; Rose, A.A.; Adler, S.S.; Aronson, S.H.; David, G.; Desmond, E.J.; Ewell, L.; Franz, A.; Guryn, W.; Haggerty, J.S.; Johnson, B.M.; Kistenev, E.; Kroon, P.J.; Mahon, J.; Makdisi, Y.I.

2002-01-01

Distributions of event-by-event fluctuations of the mean transverse momentum and mean transverse energy near mid-rapidity have been measured in Au+Au collisions at √(s NN )=130 GeV at the Relativistic Heavy-Ion Collider. By comparing the distributions to what is expected for statistically independent particle emission, the magnitude of nonstatistical fluctuations in mean transverse momentum is determined to be consistent with zero. Also, no significant nonrandom fluctuations in mean transverse energy are observed. By constructing a fluctuation model with two event classes that preserve the mean and variance of the semi-inclusive p T or e T spectra, we exclude a region of fluctuations in √(s NN )=130 GeV Au+Au collisions

Changes in Intense Precipitation Events in West Africa and the central U.S. under Global Warming

Energy Technology Data Exchange (ETDEWEB)

Cook, Kerry H. [Univ. of Texas, Austin, TX (United States); Vizy, Edward [Univ. of Texas, Austin, TX (United States)

2016-02-08

The purpose of the proposed project is to improve our understanding of the physical processes and large-scale connectivity of changes in intense precipitation events (high rainfall rates) under global warming in West Africa and the central U.S., including relationships with low-frequency modes of variability. This is in response to the requested subject area #2 “simulation of climate extremes under a changing climate … to better quantify the frequency, duration, and intensity of extreme events under climate change and elucidate the role of low frequency climate variability in modulating extremes.” We will use a regional climate model and emphasize an understanding of the physical processes that lead to an intensification of rainfall. The project objectives are as follows: 1. Understand the processes responsible for simulated changes in warm-season rainfall intensity and frequency over West Africa and the Central U.S. associated with greenhouse gas-induced global warming 2. Understand the relationship between changes in warm-season rainfall intensity and frequency, which generally occur on regional space scales, and the larger-scale global warming signal by considering modifications of low-frequency modes of variability. 3. Relate changes simulated on regional space scales to global-scale theories of how and why atmospheric moisture levels and rainfall should change as climate warms.

Individualised therapy is more cost-effective than dose intensification in patients with Crohn's disease who lose response to anti-TNF treatment

DEFF Research Database (Denmark)

Steenholdt, Casper; Brynskov, Jørn; Thomsen, Ole Østergaard

2014-01-01

OBJECTIVE: Although the reasons for secondary loss of response to infliximab (IFX) maintenance therapy in Crohn's disease vary, dose intensification is usually recommended. This study investigated the cost-effectiveness of interventions defined by an algorithm designed to identify specific reasons...... by response rates, was similar: 58% and 53%, respectively, p=0.81; difference 5% (-19% to 28%). For per-protocol patients, treatment costs were even lower (56%) in the algorithm-treated group (€ 4062 vs € 9178, presponse rates (47% vs 53%, p=0.78; difference -5% (-33% to 22...

Mechanization of Conservation Agriculture for Smallholders: Issues and Options for Sustainable Intensification

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Brian Sims

2015-05-01

Full Text Available Conservation agriculture (CA is an increasingly adopted production system to meet the goals of sustainable crop production intensification in feeding a growing world population whilst conserving natural resources. Mechanization (especially power units, seeders, rippers and sprayers is a key input for CA and smallholder farmers often have difficulties in making the necessary investments. Donors may be able to provide mechanization inputs in the short term, but this is not a sustainable solution as a machinery input supply chain needs to be built up to continue availability after external interventions cease. Local manufacture should be supported, as was the case in Brazil, but this is a slow development process, especially in sub-Saharan Africa. A more immediate solution is to equip and train CA service provision entrepreneurs. With the right equipment, selected for the needs of their local clientele, and the right technical and business management training, such entrepreneurs can make a livelihood by supplying high quality CA and other mechanization services on a fully costed basis. Elements of the required training, based on extensive field experience, are provided. To catalyse the growth of CA providers’ business, the market can be stimulated for an initial period by issuing e-vouchers for services and inputs.

Event-by-event fluctuations of the mean transverse momentum $M_{p_{T}}$ at SPS energies

CERN Document Server

Appelshäuser, Harald

2004-01-01

The study of event-by-event fluctuations has been proposed as a tool to investigate the properties of hot and dense nuclear matter created in nuclear collisions. Significant fluctuations of the mean transverse momentum beyond purely statistical ones may signal the passage of the system through the QCD phase boundary or close to the critical point. Fluctuations of M/sub PT/ provide valuable information about the dynamical evolution of A A collisions. In this contribution, recent measurements by the CERES experiment at the CERN-SPS are discussed. The analysis comprises a centrality dependent study of M/sub PT/ fluctuations near mid-rapidity in Pb-Au collisions at 40, 80, and 158 A GeV/c. The non-statistical (dynamical) contribution to M/sub PT/ fluctuations has been evaluated in terms of the fluctuation measure Sigma /sub PT/.

Climate Analogues Suggest Limited Potential for Intensification of Production on Current Croplands Under Climate Change

Science.gov (United States)

Pugh, T. A. M.; Mueller, C.; Elliott, J.; Deryng, D.; Folberth, C.; Olin, S.; Schmid, E.; Arneth, A.

2016-01-01

Climate change could pose a major challenge to efforts towards strongly increase food production over the coming decades. However, model simulations of future climate-impacts on crop yields differ substantially in the magnitude and even direction of the projected change. Combining observations of current maximum-attainable yield with climate analogues, we provide a complementary method of assessing the effect of climate change on crop yields. Strong reductions in attainable yields of major cereal crops are found across a large fraction of current cropland by 2050. These areas are vulnerable to climate change and have greatly reduced opportunity for agricultural intensification. However, the total land area, including regions not currently used for crops, climatically suitable for high attainable yields of maize, wheat and rice is similar by 2050 to the present-day. Large shifts in land-use patterns and crop choice will likely be necessary to sustain production growth rates and keep pace with demand.

Evolution in Intensity and Frequency of Extreme Events of Precipitation in Northeast Region and Brazilian Amazon in XXI Century

Science.gov (United States)

Fonseca, P. M.; Veiga, J. A.; Correia, F. S.; Brito, A. L.

2013-05-01

The aim of this research was evaluate changes in frequency and intensity of extreme events of precipitation in Brazilian Amazon and Northeast Region, doubling CO2 concentration in agreement of IPCC A2 emissions scenarios (Nakicenovic et al., 2001). For this evaluation was used ETA model (Chou et al., 2011), forced with CCSM3 Global model data (Meehl, 2006) to run 4 experiments, only for January, February and March: 1980-1990, 2000-2010, 2040-2050 and 2090-2100. Using the first decade as reference (1980-1990), was evaluated changes occurred in following decades, with a methodology to classify extremes events adapted from Frich (2002) and Gao (2006). Higher was the class, more intense is the event. An increase of 25% was observed in total precipitation in Brazilian Amazon for the end of XXI century and 12% for extreme events type 1, 9% for events type 2 and 10% for type 3. By the other hand, a 17% decrease of precipitation in Brazilian Northeast was observed, and a pronounced decay of 24% and 15% in extreme events contribution type 1 and 2 to total amount of precipitation, respectively. The difference between total normal type events was positive in this three decades compared with reference decade 1980-1990, varying positively from 4 to 6 thousand events included in normality by decade, these events was decreased in your majority of Class 1 events, which presented a decay of at least 3.500 events by each decade. This suggests an intensification of extreme events, considering that the amount of precipitation by class increased, and the number of events by class decreased. To Northeast region, an increasing in 9% of contribution to events type 3 class was observed, as well as in the frequency of this type of events (about of 700 more events). Major decreasing in number of classes extreme events occur in 2000-2010, to classes 1 and 3, with 7,2 and 5,6%, and by the end of century in class 3, with 4,5%. For the three analyzed decades a total decrease of 8.400 events was

Discrete event simulation versus conventional system reliability analysis approaches

DEFF Research Database (Denmark)

Kozine, Igor

2010-01-01

Discrete Event Simulation (DES) environments are rapidly developing and appear to be promising tools for building reliability and risk analysis models of safety-critical systems and human operators. If properly developed, they are an alternative to the conventional human reliability analysis models...... and systems analysis methods such as fault and event trees and Bayesian networks. As one part, the paper describes briefly the author’s experience in applying DES models to the analysis of safety-critical systems in different domains. The other part of the paper is devoted to comparing conventional approaches...

The effects of gallic/ferulic/caffeic acids on colour intensification and anthocyanin stability.

Science.gov (United States)

Qian, Bing-Jun; Liu, Jian-Hua; Zhao, Shu-Juan; Cai, Jian-Xiong; Jing, Pu

2017-08-01

The mechanism by which copigments stabilize colour, by protecting anthocyanin chromophores from nucleophilic attack, seems well accepted. This study was to determine effects of gallic/ferulic/caffeic acids on colour intensification and anthocyanin stability. Molecular dynamics simulations were applied to explore molecular interactions. Phenolic acids intensified the colour by 19%∼27%. Colour fading during heating followed first-order reactions with half-lives of 3.66, 9.64, 3.50, and 3.39h, whereas anthocyanin degradation, determined by the pH differential method (or HPLC-PDA), followed second-order reactions with half-lives of 3.29 (3.40), 3.43 (3.39), 2.29 (0.39), and 2.72 (0.32)h alone or with gallic/ferulic/caffeic acids, respectively, suggesting that anthocyanin degradation was faster than the colour fading. The strongest protection of gallic acids might be attributed to the shortest distance (4.37Å) of its aromatic ring to the anthocyanin (AC) panel. Hyperchromic effects induced by phenolic acids were pronounced and they obscured the accelerated anthocyanin degradation due to self-association interruption. Copyright © 2017 Elsevier Ltd. All rights reserved.

Improvement of Soil Biology Characteristics at Paddy Field by System of Rice Intensification

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Widyatmani Sih Dewi

2015-07-01

Full Text Available The aim of the research was to test the System of Rice Intensification (SRI method in improving the biological properties of paddy soil. The indicators of improvement were measured by the number of earthworm feces (cast, and the population of some microbial and nutrient content in the cast. The experiments were performed by comparing the three methods, namely: (1 SRI, (2 semi-conventional, and (3 conventional, using Randomized Completely Block Design. Each treatment was repeated nine times. The experiments were performed in the paddy fields belonging to farmers in Sukoharjo, Central Java. The result showed that the SRI (application of 1 tons ha-1 of vermicompost + 50% of inorganic fertilizer dosage tends to increase the number of earthworms cast. It is an indicator of earthworm activity in soil. Earthworms cast contains more phosphate solubilizing bacteria (12.98 x 1010cfu and N content (1.23% compared to its surrounding soil. There is a close functional relation between earthworms cast with total tiller number. SRI method is better than the other two methods to improve the biological characteristics of paddy soil that has the potential to maintain the sustainability of soil productivity.

Joko Tingkir program for estimating tsunami potential rapidly

Energy Technology Data Exchange (ETDEWEB)

Madlazim,, E-mail: m-lazim@physics.its.ac.id; Hariyono, E., E-mail: m-lazim@physics.its.ac.id [Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Surabaya (UNESA) , Jl. Ketintang, Surabaya 60231 (Indonesia)

2014-09-25

The purpose of the study was to estimate P-wave rupture durations (T{sub dur}), dominant periods (T{sub d}) and exceeds duration (T{sub 50Ex}) simultaneously for local events, shallow earthquakes which occurred off the coast of Indonesia. Although the all earthquakes had parameters of magnitude more than 6,3 and depth less than 70 km, part of the earthquakes generated a tsunami while the other events (Mw=7.8) did not. Analysis using Joko Tingkir of the above stated parameters helped understand the tsunami generation of these earthquakes. Measurements from vertical component broadband P-wave quake velocity records and determination of the above stated parameters can provide a direct procedure for assessing rapidly the potential for tsunami generation. The results of the present study and the analysis of the seismic parameters helped explain why the events generated a tsunami, while the others did not.

Rapidity dependence of strangeness enhancement factor at FAIR energies

International Nuclear Information System (INIS)

Dey, Kalyan; Bhattacharjee, B.

2014-01-01

Strange particles are produced only at the time of collisions and thus expected to carry important information of collision dynamics. Strangeness enhancement is considered to be one of the traditional signatures of formation of Quark Gluon Plasma (QGP). Due to the limitation of the detector acceptance, the past and ongoing heavy ion experiments could measure the strangeness enhancement at midrapidity only. But the future heavy ion experiment CBM at FAIR will have the access to the entire forward rapidity hemisphere and thus the experimental determination of rapidity dependent strangeness enhancement is a possibility. In this work, an attempt has therefore been made to study the rapidity dependent strangeness enhancement at FAIR energies with the help of a string based hadronic model (UrQMD). A sum of 93 million minimum biased UrQMD events have been used for the present analysis

Assessing the Effects of Grassland Management on Forage Production and Environmental Quality to Identify Paths to Ecological Intensification in Mountain Grasslands.

Science.gov (United States)

Loucougaray, Grégory; Dobremez, Laurent; Gos, Pierre; Pauthenet, Yves; Nettier, Baptiste; Lavorel, Sandra

2015-11-01

Ecological intensification in grasslands can be regarded as a process for increasing forage production while maintaining high levels of ecosystem functions and biodiversity. In the mountain Vercors massif, where dairy cattle farming is the main component of agriculture, how to achieve forage autonomy at farm level while sustaining environmental quality for tourism and local dairy products has recently stimulated local debate. As specific management is one of the main drivers of ecosystem functioning, we assessed the response of forage production and environmental quality at grassland scale across a wide range of management practices. We aimed to determine which components of management can be harnessed to better match forage production and environmental quality. We sampled the vegetation of 51 grasslands stratified across 13 grassland types. We assessed each grassland for agronomic and environmental properties, measuring forage production, forage quality, and indices based on the abundance of particular plant species such as timing flexibility, apiarian potential, and aromatic plants. Our results revealed an expected trade-off between forage production and environmental quality, notably by stressing the contrasts between sown and permanent grasslands. However, strong within-type variability in both production and environmental quality as well as in flexibility of timing of use suggests possible ways to improve this trade-off at grassland and farm scales. As achieving forage autonomy relies on increasing both forage production and grassland resilience, our results highlight the critical role of the ratio between sown and permanent grasslands as a major path for ecological intensification in mountain grasslands.

Drug persistence and need for dose intensification to adalimumab therapy; the importance of therapeutic drug monitoring in inflammatory bowel diseases.

Science.gov (United States)

Gonczi, Lorant; Kurti, Zsuzsanna; Rutka, Mariann; Vegh, Zsuzsanna; Farkas, Klaudia; Lovasz, Barbara D; Golovics, Petra A; Gecse, Krisztina B; Szalay, Balazs; Molnar, Tamas; Lakatos, Peter L

2017-08-08

Therapeutic drug monitoring (TDM) aid therapeutic decision making in patients with inflammatory bowel disease (IBD) who lose response to anti-TNF therapy. Our aim was to evaluate the frequency and predictive factors of loss of response (LOR) to adalimumab using TDM in IBD patients. One hundred twelve IBD patients (with 214 TDM measurements, CD/UC 84/28, male/female 50/62, mean age CD/UC: 36/35 years) were enrolled in this consecutive cohort from two referral centres in Hungary. Demographic data were comprehensively collected and harmonized monitoring strategy was applied. Previous and current therapy, laboratory data and clinical activity were recorded at the time of TDM. Patients were evaluated either at the time of suspected LOR or during follow-up. TDM measurements were determined by commercial ELISA (LISA TRACKER, Theradiag, France). Among 112 IBD patients, LOR/drug persistence was 25.9%/74.1%. The cumulative ADA positivity (>10 ng/mL) and low TL (<5.0 μg/mL) was 12.1% and 17.8% after 1 year and 17.3% and 29.5% after 2 years of adalimumab therapy. Dose intensification was needed in 29.5% of the patients. Female gender and ADA positivity were associated with LOR (female gender: p < 0.001, OR:7.8 CI 95%: 2.5-24.3, ADA positivity: p = 0.007 OR:3.6 CI 95%: 1.4-9.5). ADA development, low TL and need for dose intensification were frequent during adalimumab therapy and support the selective use of TDM in IBD patients treated with adalimumab. ADA positivity and gender were predictors of LOR.

Long-term nutrient fertilization and the carbon balance of permanent grassland: any evidence for sustainable intensification?

Science.gov (United States)

Fornara, Dario A.; Wasson, Elizabeth-Anne; Christie, Peter; Watson, Catherine J.

2016-09-01

Sustainable grassland intensification aims to increase plant yields while maintaining the ability of soil to act as a sink rather than sources of atmospheric CO2. High biomass yields from managed grasslands, however, can be only maintained through long-term nutrient fertilization, which can significantly affect soil carbon (C) storage and cycling. Key questions remain about (1) how long-term inorganic vs. organic fertilization influences soil C stocks, and (2) how soil C gains (or losses) contribute to the long-term C balance of managed grasslands. Using 43 years of data from a permanent grassland experiment, we show that soils not only act as significant C sinks but have not yet reached C saturation. Even unfertilized control soils showed C sequestration rates of 0.35 Mg C ha-1 yr-1 (i.e. 35 g C m-2 yr-1; 0-15 cm depth) between 1970 and 2013. High application rates of liquid manure (i.e. cattle slurry) further increased soil C sequestration to 0.86 Mg C ha-1 yr-1 (i.e. 86 g C m-2 yr-1) and a key cause of this C accrual was greater C inputs from cattle slurry. However, average coefficients of slurry-C retention in soils suggest that 85 % of C added yearly through liquid manure is lost possibly via CO2 fluxes and organic C leaching. Inorganically fertilized soils (i.e. NPK) had the lowest C-gain efficiency (i.e. unit of C gained per unit of N added) and lowest C sequestration (similar to control soils). Soils receiving cattle slurry showed higher C-gain and N-retention efficiencies compared to soils receiving NPK or pig slurry. We estimate that net rates of CO2-sequestration in the top 15 cm of the soil can offset 9-25 % of GHG (greenhouse gas) emissions from intensive management. However, because of multiple GHG sources associated with livestock farming, the net C balance of these grasslands remains positive (9-12 Mg CO2-equivalent ha-1 yr-1), thus contributing to climate change. Further C-gain efficiencies (e.g. reduced enteric fermentation and use of feed

Prevention and treatment of traumatic brain injury due to rapid-onset natural disasters

Directory of Open Access Journals (Sweden)

James L. Regens

2014-04-01

Full Text Available The prevention and treatment of traumatic brain injury (TBI attributable to rapid-onset natural disasters is a major challenge confronting disaster preparedness planners and emergency medical personnel responding to those incidents. The kinetic energy released by rapid-onset natural disasters such as earthquakes, hurricanes or typhoons, and tornadoes can cause mild, moderate or severe TBIs. As a result, neurotrauma is a major risk factor for mortality and morbidity outcomes within the spatial domain impacted by a rapid-onset natural disaster. This review article elucidates major challenges associated with immediate emergency medical response, long-term care, and prevention of post-event increases in pediatric TBIs because of child abuse when rapid-onset natural disasters occur.

Estimation of tropical cyclone heat potential in the Bay of Bengal and its role in the genesis and intensification of storms

Digital Repository Service at National Institute of Oceanography (India)

Sadhuram, Y.; Murthy, T.V.R.; Somayajulu, Y.K.

in the intensification of a storm. Warm layers of 26?C extended at least 100 m beneath the surface in these oceanic features which represent high heat potential (> 90 kJ/cm2) in the western Gulf of Mexico8,9. Monitoring of warm and cold core eddies and the regions... of Mexico, J.Phys.Oceonogr, 2 (1972) 218-224. 4 Palmen E, On the formation and structure of tropical cyclones, Geophysics, 3 (1948) 26-38. 5 Sadhuram Y, Rao B P, Rao D P, Shastri P N M & Subrahmanyam M V, Seasonal variability of cyclone heat potential...

Human activity accelerating the rapid desertification of the Mu Us Sandy Lands, North China

Science.gov (United States)

Miao, Yunfa; Jin, Heling; Cui, Jianxin

2016-01-01

Over the past several thousand years, arid and semiarid China has experienced a series of asynchronous desertification events in its semiarid sandy and desert regions, but the precise identification of the driving forces of such events has remained elusive. In this paper we identify two rapid desertification events (RDEs) at ~4.6 ± 0.2 ka BP and ~3.3 ± 0.2 ka BP from the JJ Profile, located in the eastern Mu Us Sandy Lands. These RDEs appear to have occurred immediately following periods marked by persistently frequent and intense fires. We argue that such fire patterns, directly linked to an uncontrolled human use of vegetation as fuel, played a key role in accelerating RDEs by ensuring that the land surface was degraded beyond the threshold required for rapid desertification. This would suggest that the future use of a massive and sustained ecological program of vegetation rehabilitation should reduce the risk of destructive fire. PMID:26961705

Human activity accelerating the rapid desertification of the Mu Us Sandy Lands, North China.

Science.gov (United States)

Miao, Yunfa; Jin, Heling; Cui, Jianxin

2016-03-10

Over the past several thousand years, arid and semiarid China has experienced a series of asynchronous desertification events in its semiarid sandy and desert regions, but the precise identification of the driving forces of such events has remained elusive. In this paper we identify two rapid desertification events (RDEs) at ~4.6 ± 0.2 ka BP and ~3.3 ± 0.2 ka BP from the JJ Profile, located in the eastern Mu Us Sandy Lands. These RDEs appear to have occurred immediately following periods marked by persistently frequent and intense fires. We argue that such fire patterns, directly linked to an uncontrolled human use of vegetation as fuel, played a key role in accelerating RDEs by ensuring that the land surface was degraded beyond the threshold required for rapid desertification. This would suggest that the future use of a massive and sustained ecological program of vegetation rehabilitation should reduce the risk of destructive fire.

A Rapid History of Futures Thought: From Montgolfier to the Manhattan Project.

Science.gov (United States)

Clarke, I. F.

1984-01-01

The literature of future studies has grown up rapidly in times of technological innovation and social change. Particular events and publications that have contributed most to the development of the futures movement around the world are highlighted. (Author/RM)

Probabilistic attribution of individual unprecedented extreme events

Science.gov (United States)

Diffenbaugh, N. S.

2016-12-01

The last decade has seen a rapid increase in efforts to understand the influence of global warming on individual extreme climate events. Although trends in the distributions of climate observations have been thoroughly analyzed, rigorously quantifying the contribution of global-scale warming to individual events that are unprecedented in the observed record presents a particular challenge. This paper describes a method for leveraging observations and climate model ensembles to quantify the influence of historical global warming on the severity and probability of unprecedented events. This approach uses formal inferential techniques to quantify four metrics: (1) the contribution of the observed trend to the event magnitude, (2) the contribution of the observed trend to the event probability, (3) the probability of the observed trend in the current climate and a climate without human influence, and (4) the probability of the event magnitude in the current climate and a climate without human influence. Illustrative examples are presented, spanning a range of climate variables, timescales, and regions. These examples illustrate that global warming can influence the severity and probability of unprecedented extremes. In some cases - particularly high temperatures - this change is indicated by changes in the mean. However, changes in probability do not always arise from changes in the mean, suggesting that global warming can alter the frequency with which complex physical conditions co-occur. Because our framework is transparent and highly generalized, it can be readily applied to a range of climate events, regions, and levels of climate forcing.

Local charge nonequilibrium and anomalous energy dependence of normalized moments in narrow rapidity windows

International Nuclear Information System (INIS)

Wu Yuanfang; Liu Lianshou

1990-01-01

From the study of even and odd multiplicity distributions for hadron-hadron collision in different rapidity windows, we propose a simple picture for charge correlation with nonzero correlation length and calculate the multiplicity distributions and the normalized moments in different rapidity windows at different energies. The results explain the experimentally observed coincidence and separation of even and odd distributions and also the anomalous energy dependence of normalized moments in narrow rapidity windows. The reason for the separation of even-odd distributions, appearing first at large multiplicities, is shown to be energy conservation. The special role of no-particle events in narrow rapidity windows is pointed out

Rapid Flood Map Generation from Spaceborne SAR Observations

Science.gov (United States)

Yun, S. H.; Liang, C.; Manipon, G.; Jung, J.; Gurrola, E. M.; Owen, S. E.; Hua, H.; Agram, P. S.; Webb, F.; Sacco, G. F.; Rosen, P. A.; Simons, M.

2016-12-01

The Advanced Rapid Imaging and Analysis (ARIA) team has responded to the January 2016 US Midwest Floods along the Mississippi River. Daily teleconferences with FEMA, NOAA, NGA, and USGS, provided information on precipitation and flood crest migration, based on which we coordinated with the Japanese Aerospace Exploration Agency (JAXA) through NASA headquarters for JAXA's ALOS-2 timely tasking over two paths. We produced flood extent maps using ALOS-2 SM3 mode Level 1.5 data that were provided through the International Charter and stored at the US Geological Survey's Hazards Data Distribution System (HDDS) archive. On January 6, the first four frames (70 km x 240 km) were acquired, which included the City of Memphis. We registered post-event SAR images to pre-event images, applied radiometric calibration, took a logarithm of the ratio of the two images. Two thresholds were applied to represent flooded areas that became open water (colored in blue) and flooded areas with tall vegetation (colored in red). The second path was acquired on January 11 further down along the Mississippi River. Seven frames (70 km x 420 km) were acquired and flood maps were created in the similar fashion. The maps were delivered to the FEMA as well as posted on ARIA's public website. The FEMA stated that SAR provides inspection priority for optical imagery and ground response. The ALOS-2 data and the products have been a very important source of information during this response as the flood crest has moved down stream. The SAR data continue to be an important resource during times when optical observations are often not useful. In close collaboration with FEMA and USGS, we also work on other flood events including June 2016 China Floods using European Space Agency's (ESA's) Sentienl-1 data, to produce flood extent maps and identify algorithmic needs and ARIA system's requirements to automate and rapidly produce and deliver flood maps for future events. With the addition of Sentinel-1B

Greed, grievance, leadership and external interventions in the initiation and intensification of the civil war in Angola

Directory of Open Access Journals (Sweden)

Ricardo Real P. Sousa

2016-05-01

Full Text Available Understanding the initiation of conflict is fundamental for the success of efforts in conflict prevention. The validity of the mechanisms of the “Greed and Grievance” model, alongside leadership and external interventions are tested in four periods of initiation and intensification of the conflict in Angola. All mechanisms are present but their relative relevance varies throughout the conflict. Among the mechanisms identified in each period the most relevant in the Cold War period are the international and regional interventions in 1961 and 1975 and in the post-Cold War period, the “greed” factors in 1992 (oil and diamonds, poverty and war capital and the UNITA leadership of Jonas Savimbi in 1998. The case study provides evidence that “greed” and “grievance” can be interlinked (such as in 1992 and confirms the relevance of leadership and external interventions mechanisms.

Event-by-event fluctuations of the mean transverse momentum in 40, 80, and 158 A GeV/c Pb-Au collisions

International Nuclear Information System (INIS)

Adamova, D.; Agakichiev, G.; Appelshaeuser, H.; Belaga, V.; Braun-Munzinger, P.; Campagnolo, R.; Castillo, A.; Cherlin, A.; Damjanovic, S.; Dietel, T.; Dietrich, L.; Drees, A.; Esumi, S.; Filimonov, K.; Fomenko, K.; Fraenkel, Z.; Garabatos, C.; Glaessel, P.; Hering, G.; Holeczek, J.; Kushpil, V.; Lenkeit, B.; Ludolphs, W.; Maas, A.; Marin, A.; Milosevic, J.; Milov, A.; Miskowiec, D.; Musa, L.; Panebrattsev, Yu.; Petchenova, O.; Petracek, V.; Pfeiffer, A.; Rak, J.; Ravinovich, I.; Rehak, P.; Richter, M.; Sako, H.; Schmitz, W.; Schukraft, J.; Sedykh, S.; Seipp, W.; Sharma, A.; Shimansky, S.; Slivova, J.; Specht, H.J.; Stachel, J.; Sumbera, M.; Tilsner, H.; Tserruya, I.; Wessels, J.P.; Wienold, T.; Windelband, B.; Wurm, J.P.; Xie, W.; Yurevich, S.; Yurevich, V.

2003-01-01

Measurements of event-by-event fluctuations of the mean transverse momentum in Pb-Au collisions at 40, 80, and 158 A GeV/c are presented. A significant excess of mean p T fluctuations at mid-rapidity is observed over the expectation from statistically independent particle emission. The results are somewhat smaller than recent measurements at RHIC. A possible non-monotonic behavior of the mean p T fluctuations as function of collision energy, which may have indicated that the system has passed the critical point of the QCD phase diagram in the range of μ B under investigation, has not been observed. The centrality dependence of mean p T fluctuations in Pb-Au is consistent with an extrapolation from pp collisions assuming that the non-statistical fluctuations scale with multiplicity. The results are compared to calculations by the RQMD and URQMD event generators

Cenozoic lithospheric deformation in Northeast Asia and the rapidly-aging Pacific Plate

Science.gov (United States)

Yang, Ting; Moresi, Louis; Zhao, Dapeng; Sandiford, Dan; Whittaker, Joanne

2018-06-01

Northeast Asia underwent widespread rifting and magmatic events during the Cenozoic. The geodynamic origins of these tectonic events are often linked to Pacific plate subduction beneath Northeast Asia. However, the Japan Sea did not open until the late Oligocene, tens of millions of years after Pacific Plate subduction initiation in the Paleocene. Moreover, it is still not clear why the Baikal Rift Zone extension rate increased significantly after the late Miocene, while the Japan Sea opening ceased at the same time. Geodynamic models suggest these enigmatic events are related to the rapidly-aging Pacific Plate at the trench after Izanagi-Pacific spreading ridge subduction. Subduction of the young Pacific Plate delayed the Japan Sea opening during the Eocene while advection of the old Pacific Plate towards the trench increases seafloor age rapidly, allowing the Japan Sea to open after the early Miocene. The Japan Sea opening promotes fast trench retreat and slab stagnation, with subduction-induced wedge zone convection gradually increasing its extent during this process. The active rifting center associated with wedge zone convection upwelling also shifts inland-ward during slab stagnation, preventing further Japan Sea spreading while promoting the Baikal Rift Zone extension. Our geodynamic model provides a good explanation for the temporal-spatial patterns of the Cenozoic tectonic and magmatic events in Northeast Asia.

Analysis of convection-permitting simulations for capturing heavy rainfall events over Myanmar Region

Science.gov (United States)

Acierto, R. A. E.; Kawasaki, A.

2017-12-01

Perennial flooding due to heavy rainfall events causes strong impacts on the society and economy. With increasing pressures of rapid development and potential for climate change impacts, Myanmar experiences a rapid increase in disaster risk. Heavy rainfall hazard assessment is key on quantifying such disaster risk in both current and future conditions. Downscaling using Regional Climate Models (RCM) such as Weather Research and Forecast model have been used extensively for assessing such heavy rainfall events. However, usage of convective parameterizations can introduce large errors in simulating rainfall. Convective-permitting simulations have been used to deal with this problem by increasing the resolution of RCMs to 4km. This study focuses on the heavy rainfall events during the six-year (2010-2015) wet period season from May to September in Myanmar. The investigation primarily utilizes rain gauge observation for comparing downscaled heavy rainfall events in 4km resolution using ERA-Interim as boundary conditions using 12km-4km one-way nesting method. The study aims to provide basis for production of high-resolution climate projections over Myanmar in order to contribute for flood hazard and risk assessment.

Identifying and Synchronizing Health Information Technology (HIT) Events from FDA Medical Device Reports.

Science.gov (United States)

Kang, Hong; Wang, Frank; Zhou, Sicheng; Miao, Qi; Gong, Yang

2017-01-01

Health information technology (HIT) events, a subtype of patient safety events, pose a major threat and barrier toward a safer healthcare system. It is crucial to gain a better understanding of the nature of the errors and adverse events caused by current HIT systems. The scarcity of HIT event-exclusive databases and event reporting systems indicates the challenge of identifying the HIT events from existing resources. FDA Manufacturer and User Facility Device Experience (MAUDE) database is a potential resource for HIT events. However, the low proportion and the rapid evolvement of HIT-related events present challenges for distinguishing them from other equipment failures and hazards. We proposed a strategy to identify and synchronize HIT events from MAUDE by using a filter based on structured features and classifiers based on unstructured features. The strategy will help us develop and grow an HIT event-exclusive database, keeping pace with updates to MAUDE toward shared learning.

Attribution of extreme weather and climate-related events.

Science.gov (United States)

Stott, Peter A; Christidis, Nikolaos; Otto, Friederike E L; Sun, Ying; Vanderlinden, Jean-Paul; van Oldenborgh, Geert Jan; Vautard, Robert; von Storch, Hans; Walton, Peter; Yiou, Pascal; Zwiers, Francis W

2016-01-01

Extreme weather and climate-related events occur in a particular place, by definition, infrequently. It is therefore challenging to detect systematic changes in their occurrence given the relative shortness of observational records. However, there is a clear interest from outside the climate science community in the extent to which recent damaging extreme events can be linked to human-induced climate change or natural climate variability. Event attribution studies seek to determine to what extent anthropogenic climate change has altered the probability or magnitude of particular events. They have shown clear evidence for human influence having increased the probability of many extremely warm seasonal temperatures and reduced the probability of extremely cold seasonal temperatures in many parts of the world. The evidence for human influence on the probability of extreme precipitation events, droughts, and storms is more mixed. Although the science of event attribution has developed rapidly in recent years, geographical coverage of events remains patchy and based on the interests and capabilities of individual research groups. The development of operational event attribution would allow a more timely and methodical production of attribution assessments than currently obtained on an ad hoc basis. For event attribution assessments to be most useful, remaining scientific uncertainties need to be robustly assessed and the results clearly communicated. This requires the continuing development of methodologies to assess the reliability of event attribution results and further work to understand the potential utility of event attribution for stakeholder groups and decision makers. WIREs Clim Change 2016, 7:23-41. doi: 10.1002/wcc.380 For further resources related to this article, please visit the WIREs website.

Hydrogeologic effects of natural disruptive events on nuclear waste repositories

International Nuclear Information System (INIS)

Davis, S.N.

1980-06-01

Some possible hydrogeologic effects of disruptive events that may affect repositories for nuclear waste are described. A very large number of combinations of natural events can be imagined, but only those events which are judged to be most probable are covered. Waste-induced effects are not considered. The disruptive events discussed above are placed into four geologic settings. Although the geology is not specific to given repository sites that have been considered by other agencies, the geology has been generalized from actual field data and is, therefore, considered to be physically reasonable. The geologic settings considered are: (1) interior salt domes of the Gulf Coast, (2) bedded salt of southeastern New Mexico, (3) argillaceous rocks of southern Nevanda, and (4) granitic stocks of the Basin and Range Province. Log-normal distributions of permeabilities of rock units are given for each region. Chapters are devoted to: poresity and permeability of natural materials, regional flow patterns, disruptive events (faulting, dissolution of rock forming minerals, fracturing from various causes, rapid changes of hydraulic regimen); possible hydrologic effects of disruptive events; and hydraulic fracturing

Ketamine as a Rapid Treatment for Post-Traumatic Stress Disorder

Science.gov (United States)

2011-10-01

Post - traumatic stress disorder ( PTSD ) is a debilitating anxiety disorder characterized by intrusive re-experiences of the traumatic events...08-1-0602 TITLE: Ketamine as a Rapid Treatment for Post - Traumatic Stress Disorder PRINCIPAL INVESTIGATOR: Dennis Charney...dissociative effects of ketamine but not have any sustained anxiolytic and antidepressant effects. Forty individuals diagnosed with post - traumatic

Is Sustainable Intensification Pro-Poor? Evidence from Small-Scale Farmers in Rural Tanzania

Directory of Open Access Journals (Sweden)

Kathleen Brüssow

2017-09-01

Full Text Available The transition of farming systems to higher levels of productivity without overusing natural resources is of rising interest especially in African countries, where population growth has often been larger than past productivity increases. This paper aims to contribute to the debate on whether environmentally friendly agricultural practices are compatible with economic interests. In the context of small-scale farm households in Tanzania, the analysis focuses on Conservation Agriculture (CA at different levels of agricultural output, as CA is a promising toolbox for sustainable intensification. The results are based on a household survey conducted in 2014 with 900 randomly selected small-scale farmers in rural Tanzania, i.e., in semi-arid Dodoma and in semi-humid Morogoro region. We find that mulching is most frequently applied, followed by crop rotation, fallowing, intercropping and tree planting. Logit regressions show that CA adoption is influenced by socio-economic factors, farm characteristics and the regional context. Quantile regressions explain different levels of agricultural output through variables related to the extent of using CA. They indicate that marginalized farmers have the strongest crop income effect from an increased use of mulching. With increasing levels of agricultural output, the use of mulching remains beneficial for farmers, but the effect appears less pronounced.

Individual differences in detecting rapidly presented fearful faces.

Directory of Open Access Journals (Sweden)

Dandan Zhang

Full Text Available Rapid detection of evolutionarily relevant threats (e.g., fearful faces is important for human survival. The ability to rapidly detect fearful faces exhibits high variability across individuals. The present study aimed to investigate the relationship between behavioral detection ability and brain activity, using both event-related potential (ERP and event-related oscillation (ERO measurements. Faces with fearful or neutral facial expressions were presented for 17 ms or 200 ms in a backward masking paradigm. Forty-two participants were required to discriminate facial expressions of the masked faces. The behavioral sensitivity index d' showed that the detection ability to rapidly presented and masked fearful faces varied across participants. The ANOVA analyses showed that the facial expression, hemisphere, and presentation duration affected the grand-mean ERP (N1, P1, and N170 and ERO (below 20 Hz and lasted from 100 ms to 250 ms post-stimulus, mainly in theta band brain activity. More importantly, the overall detection ability of 42 subjects was significantly correlated with the emotion effect (i.e., fearful vs. neutral on ERP (r = 0.403 and ERO (r = 0.552 measurements. A higher d' value was corresponding to a larger size of the emotional effect (i.e., fearful--neutral of N170 amplitude and a larger size of the emotional effect of the specific ERO spectral power at the right hemisphere. The present results suggested a close link between behavioral detection ability and the N170 amplitude as well as the ERO spectral power below 20 Hz in individuals. The emotional effect size between fearful and neutral faces in brain activity may reflect the level of conscious awareness of fearful faces.

1 H-NMR metabolomics: Profiling method for a rapid and efficient ...

African Journals Online (AJOL)

Principal component analysis was used to separate groups of samples and to relate known and unknown metabolites to transgenic events. The screening of 100 samples, from extraction to data mining, took 36 h. Thus, this procedure allows the rapid selection of metabolic phenotypes of interest among about 30 transgenic ...

City of Fresno peer exchange on bus rapid transit : a TPCB peer exchange

Science.gov (United States)

2013-09-11

This report highlights key recommendations and best practices identified at the peer exchange on Bus Rapid Transit (BRT), held on May 21 and May 22, 2013, in Fresno, California. This event was sponsored by the Transportation Planning Capacity Buildin...

Rapid response of a hydrologic system to volcanic activity: Masaya volcano, Nicaragua

Science.gov (United States)

Pearson, S.C.P.; Connor, C.B.; Sanford, W.E.

2008-01-01

Hydrologic systems change in response to volcanic activity, and in turn may be sensitive indicators of volcanic activity. Here we investigate the coupled nature of magmatic and hydrologic systems using continuous multichannel time series of soil temperature collected on the flanks of Masaya volcano, Nicaragua, one of the most active volcanoes in Central America. The soil temperatures were measured in a low-temperature fumarole field located 3.5 km down the flanks of the volcano. Analysis of these time series reveals that they respond extremely rapidly, on a time scale of minutes, to changes in volcanic activity also manifested at the summit vent. These rapid temperature changes are caused by increased flow of water vapor through flank fumaroles during volcanism. The soil temperature response, ~5 °C, is repetitive and complex, with as many as 13 pulses during a single volcanic episode. Analysis of the frequency spectrum of these temperature time series shows that these anomalies are characterized by broad frequency content during volcanic activity. They are thus easily distinguished from seasonal trends, diurnal variations, or individual rainfall events, which triggered rapid transient increases in temperature during 5% of events. We suggest that the mechanism responsible for the distinctive temperature signals is rapid change in pore pressure in response to magmatism, a response that can be enhanced by meteoric water infiltration. Monitoring of distal fumaroles can therefore provide insight into coupled volcanic-hydrologic-meteorologic systems, and has potential as an inexpensive monitoring tool.

Event-by-event fluctuations of the mean transverse momentum in 40, 80, and 158 A GeV/c Pb-Au collisions

Energy Technology Data Exchange (ETDEWEB)

Adamova, D.; Agakichiev, G.; Appelshaeuser, H. E-mail: appels@physi.uni-heidelberg.de; Belaga, V.; Braun-Munzinger, P.; Campagnolo, R.; Castillo, A.; Cherlin, A.; Damjanovic, S.; Dietel, T.; Dietrich, L.; Drees, A.; Esumi, S.; Filimonov, K.; Fomenko, K.; Fraenkel, Z.; Garabatos, C.; Glaessel, P.; Hering, G.; Holeczek, J.; Kushpil, V.; Lenkeit, B.; Ludolphs, W.; Maas, A.; Marin, A.; Milosevic, J.; Milov, A.; Miskowiec, D.; Musa, L.; Panebrattsev, Yu.; Petchenova, O.; Petracek, V.; Pfeiffer, A.; Rak, J.; Ravinovich, I.; Rehak, P.; Richter, M.; Sako, H.; Schmitz, W.; Schukraft, J.; Sedykh, S.; Seipp, W.; Sharma, A.; Shimansky, S.; Slivova, J.; Specht, H.J.; Stachel, J.; Sumbera, M.; Tilsner, H.; Tserruya, I.; Wessels, J.P.; Wienold, T.; Windelband, B.; Wurm, J.P.; Xie, W.; Yurevich, S.; Yurevich, V

2003-11-03

Measurements of event-by-event fluctuations of the mean transverse momentum in Pb-Au collisions at 40, 80, and 158 A GeV/c are presented. A significant excess of mean p{sub T} fluctuations at mid-rapidity is observed over the expectation from statistically independent particle emission. The results are somewhat smaller than recent measurements at RHIC. A possible non-monotonic behavior of the mean p{sub T} fluctuations as function of collision energy, which may have indicated that the system has passed the critical point of the QCD phase diagram in the range of {mu}{sub B} under investigation, has not been observed. The centrality dependence of mean p{sub T} fluctuations in Pb-Au is consistent with an extrapolation from pp collisions assuming that the non-statistical fluctuations scale with multiplicity. The results are compared to calculations by the RQMD and URQMD event generators.

Event-by-event fluctuations of the mean transverse momentum in 40, 80, and 158 A GeV/c Pb-Au collisions

CERN Document Server

Adamova, D; Appelshäuser, H; Belaga, V V; Braun-Munzinger, P; Campagnolo, R; Castillo, A; Cherlin, A; Damjanovic, S; Dietel, T; Dietrich, L; Drees, A; Esumi, S; Filimonov, K; Fomenko, K; Fraenkel, Zeev; Garabatos, C; Glässel, P; Hering, G; Holeczek, J; Kushpil, V; Lenkeit, B C; Ludolphs, W; Maas, A; Marin, A; Milosevic, J; Milov, A; Miskowiec, D; Musa, L; Panebratsev, Yu A; Petchenova, O Yu; Petracek, V; Pfeiffer, A; Rak, J; Ravinovich, I; Rehak, P; Richter, M; Sako, H; Schmitz, W; Schükraft, Jürgen; Sedykh, S; Seipp, W; Sharma, A; Shimansky, S S; Slivova, J; Specht, H J; Stachel, J; Sumbera, M; Tilsner, H; Tserruya, Itzhak; Wessels, J P; Wienold, T; Windelband, B; Wurm, J P; Xie, W; Yurevich, S; Yurevich, V I

2003-01-01

Measurements of event-by-event fluctuations of the mean transverse momentum in Pb-Au collisions at 40, 80, and 158 A GeV/c are presented. A significant excess of mean p_T fluctuations at mid-rapidity is observed over the expectation from statistically independent particle emission. The results are somewhat smaller than recent measurements at RHIC. A possible non-monotonic behaviour of the mean p_T fluctuations as function of collision energy, which may have indicated that the system has passed the critical point of the QCD phase diagram in the range of mu_B under investigation, has not been observed. The centrality dependence of mean p_T fluctuations in Pb-Au is consistent with an extrapolation from pp collisions assuming that the non-statistical fluctuations scale with multiplicity. The results are compared to calculations by the RQMD and UrQMD event generators.

Rapid Response Team activation for pediatric patients on the acute pain service.

Science.gov (United States)

Teets, Maxwell; Tumin, Dmitry; Walia, Hina; Stevens, Jenna; Wrona, Sharon; Martin, David; Bhalla, Tarun; Tobias, Joseph D

2017-11-01

Untreated pain or overly aggressive pain management may lead to adverse physiologic consequences and activation of the hospital's Rapid Response Team. This study is a quality improvement initiative that attempts to identify patient demographics and patterns associated with Rapid Response Team consultations for patients on the acute pain service. A retrospective review of all patients on the acute pain service from February 2011 until June 2015 was cross-referenced with inpatients requiring consultation from the Rapid Response Team. Two independent practitioners reviewed electronic medical records to determine which events were likely associated with pain management interventions. Over a 4-year period, 4872 patients were admitted to the acute pain service of whom 135 unique patients required Rapid Response Team consults. There were 159 unique Rapid Response Team activations among 6538 unique acute pain service consults. A subset of 27 pain management-related Rapid Response Team consultations was identified. The largest percentage of patients on the acute pain service were adolescents aged 12-17 (36%). Compared to this age group, the odds of Rapid Response Team activation were higher among infants Team consultations may help to identify patients at risk for clinical decompensation. © 2017 John Wiley & Sons Ltd.

Increasing climate whiplash in 21st century California

Science.gov (United States)

Swain, D. L.; Langenbrunner, B.; Neelin, J. D.; Hall, A. D.

2017-12-01

Temperate "Mediterranean" climate regimes across the globe are particularly susceptible to wide swings between drought and flood—of which California's rapid transition from record multi-year dryness between 2012-2016 to extreme wetness during 2016-2017 provides a dramatic example. The wide-ranging human and environmental impacts of this recent "climate whiplash" event in a highly-populated, economically critical, and biodiverse region highlight the importance of understanding weather and climate extremes at both ends of the hydroclimatic spectrum. Previous studies have examined the potential contribution of anthropogenic warming to recent California extremes, but findings to date have been mixed and primarily drought-focused. Here, we use specific historical California flood and drought events as thresholds for quantifying long-term changes in precipitation extremes using a large ensemble of multi-decadal climate model simulations (CESM-LENS). We find that greenhouse gas emissions are already responsible for a detectable increase in both wet and dry extremes across portions of California, and that increasing 21st century "climate whiplash" will likely yield large increases in the frequency of both rapid "dry-to-wet" transitions and severe flood events over a wide range of timescales. This projected intensification of California's hydrological cycle would seriously challenge the region's existing water storage, conveyance, and flood control infrastructure—even absent large changes in mean precipitation.

Heinrich Events: An Unintentional Discovery And Possible Consequences For The Future

Science.gov (United States)

Heinrich, H.

2017-12-01

Heinrich Events: An Unintentional Discovery And Its Possible Consequences For The FutureIn the mid 80ties an environmental impact assessment in relation to deep-sea dumping of medium-to-high level radioactive waste was carried out in the eastern margins of the Mid Atlantic Ridge next to the Bay of Biscaye. In one of the box corers recovered for radionuclide analysis a volcanic rock was found that triggered interest because of an unexpected geochemical feature on its surface. Subsequent investigations on the bordering sediment layer revealed hints on a massive ice rafting event possibly released from rapidly collapsing circum-Atlantic ice shields. The search for more of these events in numerous sediment cores exhibited a total of 11 layers since the end of the Saalian/Illinoian glaciation (OIS 6/5 to 2/1). The six events identified in the period OIS 4 to 2 indicated oceanographic conditions in the Northeast Atlantic Ocean that were different to those that prevailed during most time of this glacial period. Later, several authors proposed mechanisms that could have triggered the collapses, e.g. the Binge-Purge model (MacAyeal, 1993) or, access of relatively warm water to the grounding lines in conjunction with isostatic movements (Bassis, 2017). One of the consequences of rapid ice shield collapses is sea level rise. Paleo data report rates of up to several meters per century over a period of several centuries. The process described by Bassis et al. resembles to what nowadays can be observed along the ice margins of Greenland and the Antarctic where (man-made) warmed ocean water attacks the grounding lines. If this initiates something similar to a Heinrich event this is of widespread consequence for coasts, from displacement of populations to marine pollution. Thus, research on past Heinrich Events is important for understanding the future developments of the existing ice shields and climate change.

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International Development Research Centre (IDRC) Digital Library (Canada)

Southeast Asia is undergoing rapid agricultural intensification affecting crops, livestock and plantation ... Region: China, Indonesia, Thailand, Viet Nam, Canada ... Region: North of Sahara, South of Sahara, Ethiopia, Kenya, Tanzania, Sudan.

Carbon emissions from agricultural expansion and intensification in the Chaco.

Science.gov (United States)

Baumann, Matthias; Gasparri, Ignacio; Piquer-Rodríguez, María; Gavier Pizarro, Gregorio; Griffiths, Patrick; Hostert, Patrick; Kuemmerle, Tobias

2017-05-01

Carbon emissions from land-use changes in tropical dry forest systems are poorly understood, although they are likely globally significant. The South American Chaco has recently emerged as a hot spot of agricultural expansion and intensification, as cattle ranching and soybean cultivation expand into forests, and as soybean cultivation replaces grazing lands. Still, our knowledge of the rates and spatial patterns of these land-use changes and how they affected carbon emissions remains partial. We used the Landsat satellite image archive to reconstruct land-use change over the past 30 years and applied a carbon bookkeeping model to quantify how these changes affected carbon budgets. Between 1985 and 2013, more than 142 000 km 2 of the Chaco's forests, equaling 20% of all forest, was replaced by croplands (38.9%) or grazing lands (61.1%). Of those grazing lands that existed in 1985, about 40% were subsequently converted to cropland. These land-use changes resulted in substantial carbon emissions, totaling 824 Tg C between 1985 and 2013, and 46.2 Tg C for 2013 alone. The majority of these emissions came from forest-to-grazing-land conversions (68%), but post-deforestation land-use change triggered an additional 52.6 Tg C. Although tropical dry forests are less carbon-dense than moist tropical forests, carbon emissions from land-use change in the Chaco were similar in magnitude to those from other major tropical deforestation frontiers. Our study thus highlights the urgent need for an improved monitoring of the often overlooked tropical dry forests and savannas, and more broadly speaking the value of the Landsat image archive for quantifying carbon fluxes from land change. © 2016 John Wiley & Sons Ltd.

Cosmic ray event in 994 C.E. recorded in radiocarbon from Danish oak

Science.gov (United States)

Fogtmann-Schulz, A.; Østbø, S. M.; Nielsen, S. G. B.; Olsen, J.; Karoff, C.; Knudsen, M. F.

2017-08-01

We present measurements of radiocarbon in annual tree rings from the time period 980-1006 Common Era (C.E.), hereby covering the cosmic ray event in 994 C.E. The new radiocarbon record from Danish oak is based on both earlywood and latewood fractions of the tree rings, which makes it possible to study seasonal variations in 14C production. The measurements show a rapid increase of ˜10‰ from 993 to 994 C.E. in latewood, followed by a modest decline and relatively high values over the ensuing ˜10 years. This rapid increase occurs from 994 to 995 C.E. in earlywood, suggesting that the cosmic ray event most likely occurred during the period between April and June 994 C.E. Our new record from Danish oak shows strong agreement with existing Δ14C records from Japan, thus supporting the hypothesis that the 994 C.E. cosmic ray event was uniform throughout the Northern Hemisphere and therefore can be used as an astrochronological tie point to anchor floating chronologies of ancient history.

Dairy intensification in developing countries: effects of market quality on farm-level feeding and breeding practices.

Science.gov (United States)

Duncan, A J; Teufel, N; Mekonnen, K; Singh, V K; Bitew, A; Gebremedhin, B

2013-12-01

-derived income is on the increase in high market quality sites. This is accompanied by a strong increase in stall feeding at the expense of grazing. The study indicates that the first constraint to intensification of dairy production in Ethiopia is the genetic quality of the herd. There is less scope for improved AI provision in India since the cross-bred herd is mainly serviced by AI already. However, as for Ethiopia, there is considerable scope for closing yield gaps in India through improved feed use and supply. Results strongly show that well-developed markets with good procurement arrangements are key for sustainable dairy intensification.

Impact of an abrupt cooling event on interglacial methane emissions in northern peatlands

Directory of Open Access Journals (Sweden)

S. Zürcher

2013-03-01

Full Text Available Rapid changes in atmospheric methane (CH4, temperature and precipitation are documented by Greenland ice core data both for glacial times (the so called Dansgaard-Oeschger (D-O events as well as for a cooling event in the early Holocene (the 8.2 kyr event. The onsets of D-O warm events are paralleled by abrupt increases in CH4 by up to 250 ppb in a few decades. Vice versa, the 8.2 kyr event is accompanied by an intermittent decrease in CH4 of about 80 ppb over 150 yr. The abrupt CH4 changes are thought to mainly originate from source emission variations in tropical and boreal wet ecosystems, but complex process oriented bottom-up model estimates of the changes in these ecosystems during rapid climate changes are still missing. Here we present simulations of CH4 emissions from northern peatlands with the LPJ-Bern dynamic global vegetation model. The model represents CH4 production and oxidation in soils and transport by ebullition, through plant aerenchyma, and by diffusion. Parameters are tuned to represent site emission data as well as inversion-based estimates of northern wetland emissions. The model is forced with climate input data from freshwater hosing experiments using the NCAR CSM1.4 climate model to simulate an abrupt cooling event. A concentration reduction of ~10 ppb is simulated per degree K change of mean northern hemispheric surface temperature in peatlands. Peatland emissions are equally sensitive to both changes in temperature and in precipitation. If simulated changes are taken as an analogy to the 8.2 kyr event, boreal peatland emissions alone could only explain 23% of the 80 ppb decline in atmospheric methane concentration. This points to a significant contribution to source changes from low latitude and tropical wetlands to this event.

Utilizing Weather RADAR for Rapid Location of Meteorite Falls and Space Debris Re-Entry

Science.gov (United States)

Fries, Marc D.

2016-01-01

This activity utilizes existing NOAA weather RADAR imagery to locate meteorite falls and space debris falls. The near-real-time availability and spatial accuracy of these data allow rapid recovery of material from both meteorite falls and space debris re-entry events. To date, at least 22 meteorite fall recoveries have benefitted from RADAR detection and fall modeling, and multiple debris re-entry events over the United States have been observed in unprecedented detail.

Random and externally controlled occurrences of Dansgaard–Oeschger events

Directory of Open Access Journals (Sweden)

J. Lohmann

2018-05-01

Full Text Available Dansgaard–Oeschger (DO events constitute the most pronounced mode of centennial to millennial climate variability of the last glacial period. Since their discovery, many decades of research have been devoted to understand the origin and nature of these rapid climate shifts. In recent years, a number of studies have appeared that report emergence of DO-type variability in fully coupled general circulation models via different mechanisms. These mechanisms result in the occurrence of DO events at varying degrees of regularity, ranging from periodic to random. When examining the full sequence of DO events as captured in the North Greenland Ice Core Project (NGRIP ice core record, one can observe high irregularity in the timing of individual events at any stage within the last glacial period. In addition to the prevailing irregularity, certain properties of the DO event sequence, such as the average event frequency or the relative distribution of cold versus warm periods, appear to be changing throughout the glacial. By using statistical hypothesis tests on simple event models, we investigate whether the observed event sequence may have been generated by stationary random processes or rather was strongly modulated by external factors. We find that the sequence of DO warming events is consistent with a stationary random process, whereas dividing the event sequence into warming and cooling events leads to inconsistency with two independent event processes. As we include external forcing, we find a particularly good fit to the observed DO sequence in a model where the average residence time in warm periods are controlled by global ice volume and cold periods by boreal summer insolation.

Random and externally controlled occurrences of Dansgaard-Oeschger events

Science.gov (United States)

Lohmann, Johannes; Ditlevsen, Peter D.

2018-05-01

Dansgaard-Oeschger (DO) events constitute the most pronounced mode of centennial to millennial climate variability of the last glacial period. Since their discovery, many decades of research have been devoted to understand the origin and nature of these rapid climate shifts. In recent years, a number of studies have appeared that report emergence of DO-type variability in fully coupled general circulation models via different mechanisms. These mechanisms result in the occurrence of DO events at varying degrees of regularity, ranging from periodic to random. When examining the full sequence of DO events as captured in the North Greenland Ice Core Project (NGRIP) ice core record, one can observe high irregularity in the timing of individual events at any stage within the last glacial period. In addition to the prevailing irregularity, certain properties of the DO event sequence, such as the average event frequency or the relative distribution of cold versus warm periods, appear to be changing throughout the glacial. By using statistical hypothesis tests on simple event models, we investigate whether the observed event sequence may have been generated by stationary random processes or rather was strongly modulated by external factors. We find that the sequence of DO warming events is consistent with a stationary random process, whereas dividing the event sequence into warming and cooling events leads to inconsistency with two independent event processes. As we include external forcing, we find a particularly good fit to the observed DO sequence in a model where the average residence time in warm periods are controlled by global ice volume and cold periods by boreal summer insolation.

An ultra-fast fiber optic pressure sensor for blast event measurements

International Nuclear Information System (INIS)

Wu, Nan; Tian, Ye; Wang, Xingwei; Zou, Xiaotian; Fitek, John; Maffeo, Michael; Niezrecki, Christopher; Chen, Julie

2012-01-01

Soldiers who are exposed to explosions are at risk of suffering traumatic brain injury (TBI). Since the causal relationship between a blast and TBI is poorly understood, it is critical to have sensors that can accurately quantify the blast dynamics and resulting wave propagation through a helmet and skull that are imparted onto and inside the brain. To help quantify the cause of TBI, it is important to record transient pressure data during a blast event. However, very few sensors feature the capabilities of tracking the dynamic pressure transients due to the rapid change of the pressure during blast events, while not interfering with the physical material layers or wave propagation. In order to measure the pressure transients efficiently, a pressure sensor should have a high resonant frequency and a high spatial resolution. This paper describes an ultra-fast fiber optic pressure sensor based on the Fabry–Perot principle for the application of measuring the rapid pressure changes in a blast event. A shock tube experiment performed in US Army Natick Soldier Research, Development and Engineering Center has demonstrated that the resonant frequency of the sensor is 4.12 MHz, which is relatively close to the designed theoretical value of 4.113 MHz. Moreover, the experiment illustrated that the sensor has a rise time of 120 ns, which demonstrates that the sensor is capable of observing the dynamics of the pressure transient during a blast event. (paper)

How does intensification influence the operational and environmental performance of photo-Fenton processes at acidic and circumneutral pH.

Science.gov (United States)

Salazar, Luis Miguel; Grisales, Claudia Mildred; Garcia, Dorian Prato

2018-05-31

This study evaluates the technical, economical, and environmental impact of sodium persulfate (Na 2 S 2 O 8 ) as an enhancing agent in a photo-Fenton process within a solar-pond type reactor (SPR). Photo-Fenton (PF) and photo-Fenton intensified with the addition of persulfate (PFPS) processes decolorize 97% the azo dye direct blue 71 (DB71) and allow producing a highly biodegradable effluent. Intensification with persulfate allowed reducing treatment time in 33% (from 120 to 80 min) and the consumption of chemical auxiliaries needed for pH adjustment. Energy, reagents, and chemical auxiliaries are still and environmental hotspot for PF and PFPS; however, it is worth mentioning that their environmental footprint is lower than that observed for compound parabolic concentrator (CPC)-type reactors. A life-cycle assessment (LCA) confirms that H 2 O 2 , NaOH, and energy consumption are the variables with the highest impact from an environmental standpoint. The use of persulfate reduced the relative impact in 1.2 to 12% in 12 of the 18 environmental categories studied using the ReCiPe method. The PFPS process emits 1.23 kg CO 2 (CO 2 -Eqv/m 3 treated water). On the other hand, the PF process emits 1.28 kg CO 2 (CO 2 -Eqv/m 3 treated water). Process intensification, chemometric techniques, and the use of SPRs minimize the impact of some barriers (reagent and energy consumption, technical complexity of reactors, pressure drops, dirt on the reflecting surfaces, fragility of reactor materials), limiting the application of advanced oxidation systems at an industrial level, and decrease treatment cost as well as potential environmental impacts associated with energy and reagents consumption. Treatment costs for PF processes (US$0.78/m 3 ) and PFPS processes (US$0.63/m 3 ) were 20 times lower than those reported for photo-Fenton processes in CPC-type reactors.

An operational procedure for rapid flood risk assessment in Europe

Science.gov (United States)

Dottori, Francesco; Kalas, Milan; Salamon, Peter; Bianchi, Alessandra; Alfieri, Lorenzo; Feyen, Luc

2017-07-01

The development of methods for rapid flood mapping and risk assessment is a key step to increase the usefulness of flood early warning systems and is crucial for effective emergency response and flood impact mitigation. Currently, flood early warning systems rarely include real-time components to assess potential impacts generated by forecasted flood events. To overcome this limitation, this study describes the benchmarking of an operational procedure for rapid flood risk assessment based on predictions issued by the European Flood Awareness System (EFAS). Daily streamflow forecasts produced for major European river networks are translated into event-based flood hazard maps using a large map catalogue derived from high-resolution hydrodynamic simulations. Flood hazard maps are then combined with exposure and vulnerability information, and the impacts of the forecasted flood events are evaluated in terms of flood-prone areas, economic damage and affected population, infrastructures and cities.An extensive testing of the operational procedure has been carried out by analysing the catastrophic floods of May 2014 in Bosnia-Herzegovina, Croatia and Serbia. The reliability of the flood mapping methodology is tested against satellite-based and report-based flood extent data, while modelled estimates of economic damage and affected population are compared against ground-based estimations. Finally, we evaluate the skill of risk estimates derived from EFAS flood forecasts with different lead times and combinations of probabilistic forecasts. Results highlight the potential of the real-time operational procedure in helping emergency response and management.

Exploring the Early Structure of a Rapidly Decompressed Particle Bed

Science.gov (United States)

Zunino, Heather; Adrian, R. J.; Clarke, Amanda; Johnson, Blair; Arizona State University Collaboration

2017-11-01

Rapid expansion of dense, pressurized beds of fine particles subjected to rapid reduction of the external pressure is studied in a vertical shock tube. A near-sonic expansion wave impinges on the particle bed-gas interface and rapidly unloads the particle bed. A high-speed video camera captures events occurring during bed expansion. The particle bed does not expand homogeneously, but breaks down into horizontal slabs and then transforms into a cellular-type structure. There are several key parameters that affect the particle bed evolution, including particle size and initial bed height. Analyses of this bed structure evolution from experiments with varying particle sizes and initial bed heights is presented. This work is supported by the U.S. Department of Energy, National Nuclear Security Administration, Advanced Simulation and Computing Program, as a Cooperative Agreement under the Predictive Science and Academic Alliance Program, under Contract No. DE-NA0002378.

Transient paralysis during acupuncture therapy: a case report of an adverse event.

Science.gov (United States)

Beable, Anne

2013-09-01

A patient with apparently well-controlled epilepsy with a painful musculoskeletal condition was treated successfully with two sessions of acupuncture. However, 4 h after the first treatment and during the second, an adverse event involving impairment of consciousness occurred. The patient subsequently experienced an increased frequency of complex partial seizures resulting in the loss of his driving licence. A detailed retrospective review of the past medical history indicated that the patient probably had comorbidities in the form of rapid eye movement sleep behaviour disorder and dysfunctional somatosensory/vestibular processing. Acupuncture may have triggered the adverse event via shared neurosubstrates. This adverse event raises possible implications regarding safe clinical acupuncture practice.

[Titration comparative study of TOPINA Tablets in patients with localization related epilepsy: double-blind comparative study by rapid and slow titration methods].

Science.gov (United States)

Kaneko, Sunao; Inoue, Yushi; Sasagawa, Mutsuo; Kato, Masaaki

2012-04-01

To compare the tolerability and efficacy of two titration methods (rapid and slow titration) for TOPINA Tablets with different dosages and periods of escalation, a double-blind comparative study was conducted in patients with localization-related epilepsy. A total of 183 patients were randomized to either rapid titration (initial dosage 100 mg/day increased by 100-200 mg at weekly intervals) or to slow titration (initial dosage 50 mg/day increased in 50 mg/day increments at weekly intervals). TOPINA Tablets were administered for 12 weeks to the maximum dosage of 400 mg/day. The incident of adverse events leading to treatment interruptions or withdrawals was 18.9% in rapid titration and 14.8% in slow titration, with no statistical significance (p = 0.554). The incident of adverse events and adverse reactions of slow titration was slightly lower than that of rapid titration. The common adverse events and adverse reactions reported in the two titration methods were comparable and were well tolerated. On the other hand, the efficacy of slow titration, percent reduction in seizure rate and responder rate, was comparable with that of rapid titration. In conclusion, there were no significant differences of therapeutic response to TOPINA Tablets between the two titration methods.

Integrated Pest Management for Sustainable Intensification of Agriculture in Asia and Africa

Directory of Open Access Journals (Sweden)

Jules Pretty

2015-03-01

Full Text Available Integrated Pest Management (IPM is a leading complement and alternative to synthetic pesticides and a form of sustainable intensification with particular importance for tropical smallholders. Global pesticide use has grown over the past 20 years to 3.5 billion kg/year, amounting to a global market worth $45 billion. The external costs of pesticides are $4–$19 (€3–15 per kg of active ingredient applied, suggesting that IPM approaches that result in lower pesticide use will benefit, not only farmers, but also wider environments and human health. Evidence for IPM’s impacts on pesticide use and yields remains patchy. We contribute an evaluation using data from 85 IPM projects from 24 countries of Asia and Africa implemented over the past twenty years. Analysing outcomes on productivity and reliance on pesticides, we find a mean yield increase across projects and crops of 40.9% (SD 72.3, combined with a decline in pesticide use to 30.7% (SD 34.9 compared with baseline. A total of 35 of 115 (30% crop combinations resulted in a transition to zero pesticide use. We assess successes in four types of IPM projects, and find that at least 50% of pesticide use is not needed in most agroecosystems. Nonetheless, policy support for IPM is relatively rare, counter-interventions from pesticide industry common, and the IPM challenge never done as pests, diseases and weeds evolve and move.

Influences of the Saharan Air Layer on the Formation and Intensification of Hurricane Isabel (2003): Analysis of AIRS data and Numerical Simulation

Science.gov (United States)

Wu, L.; Braun, S. A.

2006-12-01

Over the past two decades, little advance has been made in prediction of tropical cyclone intensity while substantial improvements have been made in forecasting hurricane tracks. One reason is that we don't well understand the physical processes that govern tropical cyclone intensity. Recent studies have suggested that the Saharan Air Layer (SAL) may be yet another piece of the puzzle in advancing our understanding of tropical cyclone intensity change in the Atlantic basin. The SAL is an elevated mixed layer, forming as air moves across the vast Sahara Desert, in particular during boreal summer months. The SAL contains warm, dry air as well as a substantial amount of mineral dust, which can affect radiative heating and modify cloud processes. Using the retrieved temperature and humidity profiles from the AIRS suite on the NASA Aqua satellite, the SAL and its influences on the formation and intensification of Hurricane Isabel (2003) are analyzed and simulated with MM5. When the warmth and dryness of the SAL (the thermodynamic effect) is considered by relaxing the model thermodynamic state to the AIRS profiles, MM5 can well simulate the large-scale flow patterns and the activity of Hurricane Isabel in terms of the timing and location of formation and the subsequent track. Compared with the experiment without nudging the AIRS data, it is suggested that the simulated SAL effect may delay the formation and intensification of Hurricane Isabel. This case study generally confirms the argument by Dunion and Velden (2004) that the SAL can suppress Atlantic tropical cyclone activity by increasing the vertical wind shear, reducing the mean relative humidity, and stabilizing the environment at lower levels.

Intensification of biodiesel production from soybean oil and waste cooking oil in the presence of heterogeneous catalyst using high speed homogenizer.

Science.gov (United States)

Joshi, Saurabh; Gogate, Parag R; Moreira, Paulo F; Giudici, Reinaldo

2017-11-01

In the present work, high speed homogenizer has been used for the intensification of biodiesel synthesis from soybean oil and waste cooking oil (WCO) used as a sustainable feedstock. High acid value waste cooking oil (27mg of KOH/g of oil) was first esterified with methanol using sulphuric acid as catalyst in two stages to bring the acid value to desired value of 1.5mg of KOH/g of oil. Transesterification of soybean oil (directly due to lower acid value) and esterified waste cooking oil was performed in the presence of heterogeneous catalyst (CaO) for the production of biodiesel. Various experiments were performed for understanding the effect of operating parameters viz. molar ratio, catalyst loading, reaction temperature and speed of rotation of the homogenizer. For soybean oil, the maximum biodiesel yield as 84% was obtained with catalyst loading of 3wt% and molar ratio of oil to methanol of 1:10 at 50°C with 12,000rpm as the speed of rotation in 30min. Similarly biodiesel yield of 88% was obtained from waste cooking oil under identical operating conditions except for the catalyst loading which was 1wt%. Significant increase in the rate of biodiesel production with yields from soybean oil as 84% (in 30min) and from WCO as 88% (30min) was established due to the use of high speed homogenizer as compared to the conventional stirring method (requiring 2-3h for obtaining similar biodiesel yield). The observed intensification was attributed to the turbulence caused at microscale and generation of fine emulsions due to the cavitational effects. Overall it can be concluded from this study that high speed homogenizer can be used as an alternate cavitating device to efficiently produce biodiesel in the presence of heterogeneous catalysts. Copyright © 2017 Elsevier B.V. All rights reserved.

Temporal changes in glycaemic thresholds for treatment intensification in type 2 diabetes in an urban Australian setting: The Fremantle Diabetes Study.

Science.gov (United States)

Davis, Timothy M E; Chubb, Stephen A P; Curtis, Bradley H; Barraclough, Helen; Davis, Wendy A

2017-12-12

Pharmacotherapy and supportive care for diabetes in Australia are improving, with potential beneficial effects on therapeutic procrastination. To determine whether glycaemic thresholds for therapeutic intensification in type 2 diabetes changed over the 15 years between Phases of the community-based Fremantle Diabetes Study (FDS). We studied 531 Phase 1 participants (mean age 62.4 years, 54.2% males, median diabetes duration 3.0 years) with valid data from baseline assessment and five subsequent annual reviews between 1993 and 2001, and 930 Phase 2 participants (mean age 65.3 years, 53.8% males, median diabetes duration 8.0 years) with valid data from baseline and two subsequent biennial reviews between 2008 and 2015. The main outcome measure was HbA 1c at assessments before and after change in blood glucose-lowering therapy (average 6 months in Phase 1, 12 months in Phase 2). Ninety-seven participants in Phase 1 and 84 in Phase 2 progressed from diet-based management to oral hypoglycaemic agents (OHAs), and 45 and 85 participants, respectively, progressed from diet/OHAs to insulin. The median HbA 1c was 7.5% (58 mmol/mol) and 6.9% (52 mmol/mol) before OHA initiation in Phases 1 and 2, respectively, and 9.1% (76 mmol/mol) and 7.8% (62 mmol/mol), respectively, before insulin initiation. There were median HbA 1c falls of 0.3% (3 mmol/mol) and 1.5% (16 mmol/mol) after OHA and insulin initiation in Phase 1 but no statistically significant changes in Phase 2. HbA 1c thresholds triggering treatment intensification fell between FDS Phases, suggesting a more proactive approach to management of glycaemia over time. This article is protected by copyright. All rights reserved.

Environmental consequences of rapid urbanization in zhejiang province, East china.

Science.gov (United States)

Yang, Xuchao; Yue, Wenze; Xu, Honghui; Wu, Jingsheng; He, Yue

2014-07-11

Since reforms carried out in the late 1970s, China has experienced unprecedented rates of urban growth. Remote sensing data and surface observational data are used to investigate the urbanization process and related environmental consequences, focusing on extreme heat events and air pollution, in Zhejiang Province (ZJP, East China). Examination of satellite-measured nighttime light data indicates rapid urbanization in ZJP during the past decade, initially forming three urban clusters. With rapid urban sprawl, a significant Urban Heat Island (UHI) effect has emerged. During extreme heat events in summer, the UHI effect significantly exacerbates nocturnal heat stress in highly urbanized areas. Taking a long-term view, urbanization also causes additional hot days and hot degree days in urban areas. Urbanization also imposes a heavy burden on local and regional air quality in ZJP. Degraded visibility and an increase in haze days are observed at most meteorological stations, especially in the three urban clusters. The results show that urbanization has led to serious environmental problems in ZJP, not only on the city scale, but also on the regional scale. Maintaining a balance between the continuing process of urbanization and environmental sustainability is a major issue facing the local government.

Event recognition in personal photo collections via multiple instance learning-based classification of multiple images

Science.gov (United States)

Ahmad, Kashif; Conci, Nicola; Boato, Giulia; De Natale, Francesco G. B.

2017-11-01

Over the last few years, a rapid growth has been witnessed in the number of digital photos produced per year. This rapid process poses challenges in the organization and management of multimedia collections, and one viable solution consists of arranging the media on the basis of the underlying events. However, album-level annotation and the presence of irrelevant pictures in photo collections make event-based organization of personal photo albums a more challenging task. To tackle these challenges, in contrast to conventional approaches relying on supervised learning, we propose a pipeline for event recognition in personal photo collections relying on a multiple instance-learning (MIL) strategy. MIL is a modified form of supervised learning and fits well for such applications with weakly labeled data. The experimental evaluation of the proposed approach is carried out on two large-scale datasets including a self-collected and a benchmark dataset. On both, our approach significantly outperforms the existing state-of-the-art.

Comparison of event landslide inventories: the Pogliaschina catchment test case, Italy

Science.gov (United States)

Mondini, A. C.; Viero, A.; Cavalli, M.; Marchi, L.; Herrera, G.; Guzzetti, F.

2014-07-01

Event landslide inventory maps document the extent of populations of landslides caused by a single natural trigger, such as an earthquake, an intense rainfall event, or a rapid snowmelt event. Event inventory maps are important for landslide susceptibility and hazard modelling, and prove useful to manage residual risk after a landslide-triggering event. Standards for the preparation of event landslide inventory maps are lacking. Traditional methods are based on the visual interpretation of stereoscopic aerial photography, aided by field surveys. New and emerging techniques exploit remotely sensed data and semi-automatic algorithms. We describe the production and comparison of two independent event inventories prepared for the Pogliaschina catchment, Liguria, Northwest Italy. The two inventories show landslides triggered by an intense rainfall event on 25 October 2011, and were prepared through the visual interpretation of digital aerial photographs taken 3 days and 33 days after the event, and by processing a very-high-resolution image taken by the WorldView-2 satellite 4 days after the event. We compare the two inventories qualitatively and quantitatively using established and new metrics, and we discuss reasons for the differences between the two landslide maps. We expect that the results of our work can help in deciding on the most appropriate method to prepare reliable event inventory maps, and outline the advantages and the limitations of the different approaches.

Tidal Disruption Events from Eccentric Nuclear Disks

Science.gov (United States)

Wernke, Heather N.; Madigan, Ann-Marie

2018-04-01

Stars that get too close to a supermassive black hole are in danger of being tidally disrupted. Stellar two-body relaxation is commonly assumed to be the main driver of these events. Recent work has shown, however, that secular gravitational torques from eccentric nuclear disks can push stars to extreme eccentricities at much higher rates than predicted by two-body relaxation. This work did not include the effects of general relativity, however, which could quench secular torques via rapid apsidal precession. Here we show that, for a star in danger of disruption, general relativity acts on a timescale of less than an orbital period. This short timescale means that general relativity does not have enough time to have a major effect on the orbit. When driven by secular torques from eccentric nuclear disks, tidal disruption event rates are not affected by general relativity.

Disaster Response Modeling Through Discrete-Event Simulation

Science.gov (United States)

Wang, Jeffrey; Gilmer, Graham

2012-01-01

Organizations today are required to plan against a rapidly changing, high-cost environment. This is especially true for first responders to disasters and other incidents, where critical decisions must be made in a timely manner to save lives and resources. Discrete-event simulations enable organizations to make better decisions by visualizing complex processes and the impact of proposed changes before they are implemented. A discrete-event simulation using Simio software has been developed to effectively analyze and quantify the imagery capabilities of domestic aviation resources conducting relief missions. This approach has helped synthesize large amounts of data to better visualize process flows, manage resources, and pinpoint capability gaps and shortfalls in disaster response scenarios. Simulation outputs and results have supported decision makers in the understanding of high risk locations, key resource placement, and the effectiveness of proposed improvements.

Rapid SAR and GPS Measurements and Models for Hazard Science and Situational Awareness

Science.gov (United States)

Owen, S. E.; Yun, S. H.; Hua, H.; Agram, P. S.; Liu, Z.; Moore, A. W.; Rosen, P. A.; Simons, M.; Webb, F.; Linick, J.; Fielding, E. J.; Lundgren, P.; Sacco, G. F.; Polet, J.; Manipon, G.

2016-12-01

The Advanced Rapid Imaging and Analysis (ARIA) project for Natural Hazards is focused on rapidly generating higher level geodetic imaging products and placing them in the hands of the solid earth science and local, national, and international natural hazard communities by providing science product generation, exploration, and delivery capabilities at an operational level. Space-based geodetic measurement techniques such as Interferometric Synthetic Aperture Radar (InSAR), Differential Global Positioning System (DGPS), SAR-based change detection, and image pixel tracking have recently become critical additions to our toolset for understanding and mapping the damage caused by earthquakes, volcanic eruptions, landslides, and floods. Analyses of these data sets are still largely handcrafted following each event and are not generated rapidly and reliably enough for response to natural disasters or for timely analysis of large data sets. The ARIA project, a joint venture co-sponsored by California Institute of Technology (Caltech) and by NASA through the Jet Propulsion Laboratory (JPL), has been capturing the knowledge applied to these responses and building it into an automated infrastructure to generate imaging products in near real-time that can improve situational awareness for disaster response. In addition, the ARIA project is developing the capabilities to provide automated imaging and analysis capabilities necessary to keep up with the imminent increase in raw data from geodetic imaging missions planned for launch by NASA, as well as international space agencies. We will present the progress we have made on automating the analysis of SAR data for hazard monitoring and response using data from Sentinel 1a/b as well as continuous GPS stations. Since the beginning of our project, our team has imaged events and generated response products for events around the world. These response products have enabled many conversations with those in the disaster response community

Algal and water-quality data for Rapid Creek and Canyon Lake near Rapid City, South Dakota, 2007

Science.gov (United States)

Hoogestraat, Galen K.; Putnam, Larry D.; Graham, Jennifer L.

2008-01-01

This report summarizes the results of algae and water-quality sampling on Rapid Creek and Canyon Lake during May and September 2007. The overall purpose of the study was to determine the algal community composition of Rapid Creek and Canyon Lake in relation to organisms that are known producers of unwanted tastes and odors in drinking-water supplies. Algal assemblage structure (phytoplankton and periphyton) was examined at 16 sites on Rapid Creek and Canyon Lake during May and September 2007, and actinomycetes bacteria were sampled at the Rapid City water treatment plant intake in May 2007, to determine if taste-and-odor producing organisms were present. During the May 2007 sampling, 3 Rapid Creek sites and 4 Canyon Lake sites were quantitatively sampled for phytoplankton in the water column, 7 Rapid Creek sites were quantitatively sampled for attached periphyton, and 4 lake and retention pond sites were qualitatively sampled for periphyton. Five Rapid Creek sites were sampled for geosmin and 2-methylisoborneol, two common taste-and-odor causing compounds known to affect water supplies. During the September 2007 sampling, 4 Rapid Creek sites were quantitatively sampled for attached periphyton, and 3 Canyon Lake sites were qualitatively sampled for periphyton. Water temperature, dissolved oxygen, pH, and specific conductance were measured during each sampling event. Methods of collection and sample analysis are presented for the various types of biological and chemical constituent samples. Diatoms comprised 91-100 percent of the total algal biovolume in periphyton samples collected during May and September. Cyanobacteria (also called blue-green algae) were detected in 7 of the 11 quantitative periphyton samples and ranged from 0.01 to 2.0 percent of the total biovolume. Cyanobacteria were present in 3 of the 7 phytoplankton samples collected in May, but the relative biovolumes were small (0.01-0.2 percent). Six of seven qualitative samples collected from Canyon Lake

Exploring eco-health in China and Southeast Asia | IDRC ...

International Development Research Centre (IDRC) Digital Library (Canada)

2017-04-12

Apr 12, 2017 ... As nations rapidly develop, agriculture intensifies, providing numerous economic benefits. But intensification can also damage the environment and pose ... The Field Building Leadership Initiative, supported by IDRC, aims to ...

OBEST: The Object-Based Event Scenario Tree Methodology

International Nuclear Information System (INIS)

WYSS, GREGORY D.; DURAN, FELICIA A.

2001-01-01

Event tree analysis and Monte Carlo-based discrete event simulation have been used in risk assessment studies for many years. This report details how features of these two methods can be combined with concepts from object-oriented analysis to develop a new risk assessment methodology with some of the best features of each. The resultant Object-Based Event Scenarios Tree (OBEST) methodology enables an analyst to rapidly construct realistic models for scenarios for which an a priori discovery of event ordering is either cumbersome or impossible (especially those that exhibit inconsistent or variable event ordering, which are difficult to represent in an event tree analysis). Each scenario produced by OBEST is automatically associated with a likelihood estimate because probabilistic branching is integral to the object model definition. The OBEST method uses a recursive algorithm to solve the object model and identify all possible scenarios and their associated probabilities. Since scenario likelihoods are developed directly by the solution algorithm, they need not be computed by statistical inference based on Monte Carlo observations (as required by some discrete event simulation methods). Thus, OBEST is not only much more computationally efficient than these simulation methods, but it also discovers scenarios that have extremely low probabilities as a natural analytical result--scenarios that would likely be missed by a Monte Carlo-based method. This report documents the OBEST methodology, the demonstration software that implements it, and provides example OBEST models for several different application domains, including interactions among failing interdependent infrastructure systems, circuit analysis for fire risk evaluation in nuclear power plants, and aviation safety studies

Estimating shaking-induced casualties and building damage for global earthquake events: a proposed modelling approach

Science.gov (United States)

So, Emily; Spence, Robin

2013-01-01

Recent earthquakes such as the Haiti earthquake of 12 January 2010 and the Qinghai earthquake on 14 April 2010 have highlighted the importance of rapid estimation of casualties after the event for humanitarian response. Both of these events resulted in surprisingly high death tolls, casualties and survivors made homeless. In the Mw = 7.0 Haiti earthquake, over 200,000 people perished with more than 300,000 reported injuries and 2 million made homeless. The Mw = 6.9 earthquake in Qinghai resulted in over 2,000 deaths with a further 11,000 people with serious or moderate injuries and 100,000 people have been left homeless in this mountainous region of China. In such events relief efforts can be significantly benefitted by the availability of rapid estimation and mapping of expected casualties. This paper contributes to ongoing global efforts to estimate probable earthquake casualties very rapidly after an earthquake has taken place. The analysis uses the assembled empirical damage and casualty data in the Cambridge Earthquake Impacts Database (CEQID) and explores data by event and across events to test the relationships of building and fatality distributions to the main explanatory variables of building type, building damage level and earthquake intensity. The prototype global casualty estimation model described here uses a semi-empirical approach that estimates damage rates for different classes of buildings present in the local building stock, and then relates fatality rates to the damage rates of each class of buildings. This approach accounts for the effect of the very different types of buildings (by climatic zone, urban or rural location, culture, income level etc), on casualties. The resulting casualty parameters were tested against the overall casualty data from several historical earthquakes in CEQID; a reasonable fit was found.

Major rapid weight loss induces changes in cardiac repolarization

DEFF Research Database (Denmark)

Vedel-Larsen, Esben; Iepsen, Eva Winning; Lundgren, Julie

2016-01-01

INTRODUCTION: Obesity is associated with increased all-cause mortality, but weight loss may not decrease cardiovascular events. In fact, very low calorie diets have been linked to arrhythmias and sudden death. The QT interval is the standard marker for cardiac repolarization, but T-wave morphology...... analysis has been suggested as a more sensitive method to identify changes in cardiac repolarization. We examined the effect of a major and rapid weight loss on T-wave morphology. METHODS AND RESULTS: Twenty-six individuals had electrocardiograms (ECG) taken before and after eight weeks of weight loss......A1c (pweight loss induces changes in cardiac repolarization. Monitoring of MCS during calorie restriction makes it possible to detect repolarization changes with higher discriminative power than the QT-interval during major rapid weight...

Raising Crop Productivity in Africa through Intensification

Directory of Open Access Journals (Sweden)

Zerihun Tadele

2017-03-01

Full Text Available The population of Africa will double in the next 33 years to reach 2.5 billion by 2050. Although roughly 60% of the continent’s population is engaged in agriculture, the produce from this sector cannot feed its citizens. Hence, in 2013 alone, Africa imported 56.5 million tons of wheat, maize, and soybean at the cost of 18.8 billion USD. Although crops cultivated in Africa play a vital role in their contribution to Food Security, they produce inferior yields compared to those in other parts of the world. For instance, the average cereal yield in Africa is only 1.6 t·ha−1 compared to the global 3.9 t·ha−1. Low productivity in Africa is also related to poor soil fertility and scarce moisture, as well as a variety of insect pests, diseases, and weeds. While moisture scarcity is responsible for up to 60% of yield losses in some African staple cereals, insect pests inflict annually substantial crop losses. In order to devise a strategy towards boosting crop productivity on the continent where food insecurity is most prevalent, these production constraints should be investigated and properly addressed. This review focuses on conventional (also known as genetic intensification in which crop productivity is raised through breeding for cultivars with high yield-potential and those that thrive well under diverse and extreme environmental conditions. Improved crop varieties alone do not boost crop productivity unless supplemented with optimum soil, water, and plant management practices as well as the promotion of policies pertaining to inputs, credit, extension, and marketing. Studies in Kenya and Uganda have shown that the yield of cassava can be increased by 140% in farmers’ fields using improved varieties and management practices. In addition to traditional organic and inorganic fertilizers, biochar and African Dark Earths have been found to improve soil properties and to enhance productivity, although their availability and affordability to

Rapid decompression and desorption induced energetic failure in coal

Directory of Open Access Journals (Sweden)

Shugang Wang

2015-06-01

Full Text Available In this study, laboratory experiments are conducted to investigate the rapid decompression and desorption induced energetic failure in coal using a shock tube apparatus. Coal specimens are recovered from Colorado at a depth of 610 m. The coal specimens are saturated with the strong sorbing gas CO2 for a certain period and then the rupture disc is suddenly broken on top of the shock tube to generate a shock wave propagating upwards and a rarefaction wave propagating downwards through the specimen. This rapid decompression and desorption has the potential to cause energetic fragmentation in coal. Three types of behaviors in coal after rapid decompression are found, i.e. degassing without fragmentation, horizontal fragmentation, and vertical fragmentation. We speculate that the characteristics of fracture network (e.g. aperture, spacing, orientation and stiffness and gas desorption play a role in this dynamic event as coal can be considered as a dual porosity, dual permeability, dual stiffness sorbing medium. This study has important implications in understanding energetic failure process in underground coal mines such as coal gas outbursts.

Event-by-event jet quenching

Energy Technology Data Exchange (ETDEWEB)

Fries, R.J.; Rodriguez, R.; Ramirez, E.

2010-08-14

High momentum jets and hadrons can be used as probes for the quark gluon plasma (QGP) formed in nuclear collisions at high energies. We investigate the influence of fluctuations in the fireball on jet quenching observables by comparing propagation of light quarks and gluons through averaged, smooth QGP fireballs with event-by-event jet quenching using realistic inhomogeneous fireballs. We find that the transverse momentum and impact parameter dependence of the nuclear modification factor R{sub AA} can be fit well in an event-by-event quenching scenario within experimental errors. However the transport coefficient {cflx q} extracted from fits to the measured nuclear modification factor R{sub AA} in averaged fireballs underestimates the value from event-by-event calculations by up to 50%. On the other hand, after adjusting {cflx q} to fit R{sub AA} in the event-by-event analysis we find residual deviations in the azimuthal asymmetry v{sub 2} and in two-particle correlations, that provide a possible faint signature for a spatial tomography of the fireball. We discuss a correlation function that is a measure for spatial inhomogeneities in a collision and can be constrained from data.

Event-by-event jet quenching

Energy Technology Data Exchange (ETDEWEB)

Rodriguez, R. [Cyclotron Institute and Physics Department, Texas A and M University, College Station, TX 77843 (United States); Fries, R.J., E-mail: rjfries@comp.tamu.ed [Cyclotron Institute and Physics Department, Texas A and M University, College Station, TX 77843 (United States); RIKEN/BNL Research Center, Brookhaven National Laboratory, Upton, NY 11973 (United States); Ramirez, E. [Physics Department, University of Texas El Paso, El Paso, TX 79968 (United States)

2010-09-27

High momentum jets and hadrons can be used as probes for the quark gluon plasma (QGP) formed in nuclear collisions at high energies. We investigate the influence of fluctuations in the fireball on jet quenching observables by comparing propagation of light quarks and gluons through averaged, smooth QGP fireballs with event-by-event jet quenching using realistic inhomogeneous fireballs. We find that the transverse momentum and impact parameter dependence of the nuclear modification factor R{sub AA} can be fit well in an event-by-event quenching scenario within experimental errors. However the transport coefficient q extracted from fits to the measured nuclear modification factor R{sub AA} in averaged fireballs underestimates the value from event-by-event calculations by up to 50%. On the other hand, after adjusting q to fit R{sub AA} in the event-by-event analysis we find residual deviations in the azimuthal asymmetry v{sub 2} and in two-particle correlations, that provide a possible faint signature for a spatial tomography of the fireball. We discuss a correlation function that is a measure for spatial inhomogeneities in a collision and can be constrained from data.

BUDIDAYA UDANG VANAME (Litopenaeus vannamei TEKNOLOGI INTENSIF MENGGUNAKAN BENIH TOKOLAN

Directory of Open Access Journals (Sweden)

Markus Mangampa

2016-11-01

Full Text Available Salah satu jenis udang yang cukup potensial untuk dikembangkan adalah udang vaname (Litopenaeus vannamei. Budidaya ini berkembang dengan teknologi intensif, namun terbatas pada golongan masyarakat menengah ke atas (padat modal. Riset ini bertujuan untuk mendapatkan data dan informasi pengaruh penggunaan tokolan terhadap produksi, Rasio Konversi Pakan (RKP pada pembesaran udang vaname teknologi intensif. Riset ini dilaksanakan di tambak Punaga, Takalar, Instalasi Balai Riset Perikanan Budidaya Air Payau (BRPBAP, menggunakan empat petak masing masing berukuran 4.000 m2/petak. Hewan uji adalah udang vaname dengan perlakuan: (A pembesaran dengan tebar benur (PL-12, dan (B pembesaran dengan tebar tokolan (PL-27. Setiap perlakuan dengan 2 ulangan, kepadatan benur dan tokolan adalah 50 ekor/m2, dan pemeliharaan berlangsung 80 hari di tambak. Hasil yang diperoleh pada perlakuan B memperlihatkan pertumbuhan mutlak (11,114±0,258 g/ekor, sintasan (92,55±0,23%, produksi (2.087,5±88,2 kg/petak lebih tinggi daripada perlakuan A yaitu: pertumbuhan mutlak (10,085±0,120 g/ekor, sintasan (90,83±8,51%, produksi (1.831,0±149,9 kg/petak, namun ketiga peubah ini berbeda tidak nyata antara kedua perlakuan. RKP lebih rendah pada perlakuan B (1,096±0,034 berbeda nyata dengan perlakuan A (1,257±0,048. Peubah kualitas air memperlihatkan sebaran kisaran yang merata untuk kedua perlakuan, kecuali nitrit (NO2 memperlihatkan kisaran yang tinggi pada perlakuan B (0,18235 mg/L dibandingkan dengan perlakuan A (0,0328 mg/L pada akhir penelitian. Hal ini disebabkan waktu panen yang berbeda sesuai dengan kondisi musim yaitu kualitas air sumber semakin menurun. Kualitas air sumber yang menurun ini diikuti oleh meningkatnya total vibrio di air laut mencapai; 4,33104 cfu/mL dibandingkan dalam air tambak 829.102 cfu/mL. Kesimpulan memperlihatkan bahwa penggunaan tokolan (PL-27 menghasilkan produksi yang tinggi dan rasio konversi pakan yang rendah. One species of shrimps that

Uranium isotope evidence for two episodes of deoxygenation during Oceanic Anoxic Event 2

Science.gov (United States)

Clarkson, Matthew O.; Stirling, Claudine H.; Jenkyns, Hugh C.; Dickson, Alexander J.; Porcelli, Don; Moy, Christopher M.; Pogge von Strandmann, Philip A. E.; Cooke, Ilsa R.; Lenton, Timothy M.

2018-03-01

Oceanic Anoxic Event 2 (OAE 2), occurring ˜94 million years ago, was one of the most extreme carbon cycle and climatic perturbations of the Phanerozoic Eon. It was typified by a rapid rise in atmospheric CO2, global warming, and marine anoxia, leading to the widespread devastation of marine ecosystems. However, the precise timing and extent to which oceanic anoxic conditions expanded during OAE 2 remains unresolved. We present a record of global ocean redox changes during OAE 2 using a combined geochemical and carbon cycle modeling approach. We utilize a continuous, high-resolution record of uranium isotopes in pelagic and platform carbonate sediments to quantify the global extent of seafloor anoxia during OAE 2. This dataset is then compared with a dynamic model of the coupled global carbon, phosphorus, and uranium cycles to test hypotheses for OAE 2 initiation. This unique approach highlights an intra-OAE complexity that has previously been underconstrained, characterized by two expansions of anoxia separated by an episode of globally significant reoxygenation coincident with the “Plenus Cold Event.” Each anoxic expansion event was likely driven by rapid atmospheric CO2 injections from multiphase Large Igneous Province activity.

No evident spatial genetic structuring in the rapidly declining Black-tailed Godwit Limosa limosa in the Netherlands

NARCIS (Netherlands)

Trimbos, K.B.; Kentie, R.; Verkuil, Y.; Musters, C.J.M.; Piersma, Th.; Snoo, de G.R.

2011-01-01

With 40% of the European Black-tailed Godwit population breeding in The Netherlands, this country harbours internationally significant numbers of this species. However, ongoing agricultural intensification has resulted in the fragmentation of the population and drastic population declines since

Role of the Convective Scheme in Modeling Initiation and Intensification of Tropical Depressions over the North Atlantic

Science.gov (United States)

Duvel, Jean Philippe; Camargo, Suzana; Sobel, Adam

2016-04-01

Modifications of the large-scale environment related to intraseasonal (MJO) and interannual (ENSO) time-scale variability or to global climate warming may have important impacts on the tropical cyclonic activity. This sensitivity of tropical cyclones (TC) on environmental changes can now be studied using General Circulation Models (GCM). Before doing sensitivity studies with a GCM, it is interesting to assess the representation of the TC activity for different configurations (resolution, parameterization) of the GCM in present climate conditions and to trace possible causes of bias in TC number, location or strength. A possible approach to do this assessment is to separate initiation and intensification processes. By using either GCM output, or meteorological analysis combined to TC observation databases, it is possible to study the condition of formation of tropical depressions vortices (TDV) at an early stage and their possible intensification into a TC (say the Tropical Storm stage). We use the LMDZ GCM to study the sensitivity of TDV characteristics to different entrainment and closure formulations of the convective scheme. The study focuses on the Tropical North Atlantic using the "zoom" capability of the LMDZ GCM. The horizontal resolution of the model is set to 0.75° over a large region of the North Atlantic and West Africa. The GCM is free to run in this region and is tied to ERA-Interim reanalysis outside that region, with intermediate relaxation times in-between. We use the Tiedtke convective scheme with entrainment and closure based on the moisture convergence, or with an entrainment based on the relative humidity of the environment, and additionally a closure based on CAPE. Each configuration is run for 10 years between 2000 and 2009 with prescribed SST. In summary, the convective entrainment based on the relative humidity in the environment deepens the TDV in LMDZ, resulting in more TDV and TC. The convective closure mitigates this tendency and

Longitudinal decorrelation measures of flow magnitude and event-plane angles in ultrarelativistic nuclear collisions

Science.gov (United States)

BoŻek, Piotr; Broniowski, Wojciech

2018-03-01

We discuss the forward-backward correlations of harmonic flow in Pb +Pb collisions at the CERN Large Hadron Collider, applying standard multibin measures as well as new measures proposed here. We illustrate the methods with hydrodynamic model simulations based on event-by-event initial conditions from the wounded quark model with asymmetric rapidity emission profiles. Within the model, we examine independently the event-plane angle and the flow magnitude decorrelations. We find a specific hierarchy between various flow decorrelation measures and confirm certain factorization relations. We find qualitative agreement of the model and the data from the ATLAS and CMS Collaborations.

The Rapid Ice Sheet Change Observatory (RISCO)

Science.gov (United States)

Morin, P.; Howat, I. M.; Ahn, Y.; Porter, C.; McFadden, E. M.

2010-12-01

The recent expansion of observational capacity from space has revealed dramatic, rapid changes in the Earth’s ice cover. These discoveries have fundamentally altered how scientists view ice-sheet change. Instead of just slow changes in snow accumulation and melting over centuries or millennia, important changes can occur in sudden events lasting only months, weeks, or even a single day. Our understanding of these short time- and space-scale processes, which hold important implications for future global sea level rise, has been impeded by the low temporal and spatial resolution, delayed sensor tasking, incomplete coverage, inaccessibility and/or high cost of data available to investigators. New cross-agency partnerships and data access policies provide the opportunity to dramatically improve the resolution of ice sheet observations by an order of magnitude, from timescales of months and distances of 10’s of meters, to days and meters or less. Advances in image processing technology also enable application of currently under-utilized datasets. The infrastructure for systematically gathering, processing, analyzing and distributing these data does not currently exist. Here we present the development of a multi-institutional, multi-platform observatory for rapid ice change with the ultimate objective of helping to elucidate the relevant timescales and processes of ice sheet dynamics and response to climate change. The Rapid Ice Sheet Observatory (RISCO) gathers observations of short time- and space-scale Cryosphere events and makes them easily accessible to investigators, media and general public. As opposed to existing data centers, which are structured to archive and distribute diverse types of raw data to end users with the specialized software and skills to analyze them, RISCO focuses on three types of geo-referenced raster (image) data products in a format immediately viewable with commonly available software. These three products are (1) sequences of images

Large-scale flows, sheet plumes and strong magnetic fields in a rapidly rotating spherical dynamo

Science.gov (United States)

Takahashi, F.

2011-12-01

Mechanisms of magnetic field intensification by flows of an electrically conducting fluid in a rapidly rotating spherical shell is investigated. Bearing dynamos of the Eartn and planets in mind, the Ekman number is set at 10-5. A strong dipolar solution with magnetic energy 55 times larger than the kinetic energy of thermal convection is obtained. In a regime of small viscosity and inertia with the strong magnetic field, convection structure consists of a few large-scale retrograde flows in the azimuthal direction and sporadic thin sheet-like plumes. The magnetic field is amplified through stretching of magnetic lines, which occurs typically through three types of flow: the retrograde azimuthal flow near the outer boundary, the downwelling flow of the sheet plume, and the prograde azimuthal flow near the rim of the tangent cylinder induced by the downwelling flow. It is found that either structure of current loops or current sheets is accompanied in each flow structure. Current loops emerge as a result of stretching the magnetic lines along the magnetic field, wheres the current sheets are formed to counterbalance the Coriolis force. Convection structure and processes of magnetic field generation found in the present model are distinct from those in models at larger/smaller Ekman number.

Event-based text mining for biology and functional genomics

Science.gov (United States)

Thompson, Paul; Nawaz, Raheel; McNaught, John; Kell, Douglas B.

2015-01-01

The assessment of genome function requires a mapping between genome-derived entities and biochemical reactions, and the biomedical literature represents a rich source of information about reactions between biological components. However, the increasingly rapid growth in the volume of literature provides both a challenge and an opportunity for researchers to isolate information about reactions of interest in a timely and efficient manner. In response, recent text mining research in the biology domain has been largely focused on the identification and extraction of ‘events’, i.e. categorised, structured representations of relationships between biochemical entities, from the literature. Functional genomics analyses necessarily encompass events as so defined. Automatic event extraction systems facilitate the development of sophisticated semantic search applications, allowing researchers to formulate structured queries over extracted events, so as to specify the exact types of reactions to be retrieved. This article provides an overview of recent research into event extraction. We cover annotated corpora on which systems are trained, systems that achieve state-of-the-art performance and details of the community shared tasks that have been instrumental in increasing the quality, coverage and scalability of recent systems. Finally, several concrete applications of event extraction are covered, together with emerging directions of research. PMID:24907365

Re-presentations of space in Hollywood movies: an event-indexing analysis.

Science.gov (United States)

Cutting, James; Iricinschi, Catalina

2015-03-01

Popular movies present chunk-like events (scenes and subscenes) that promote episodic, serial updating of viewers' representations of the ongoing narrative. Event-indexing theory would suggest that the beginnings of new scenes trigger these updates, which in turn require more cognitive processing. Typically, a new movie event is signaled by an establishing shot, one providing more background information and a longer look than the average shot. Our analysis of 24 films reconfirms this. More important, we show that, when returning to a previously shown location, the re-establishing shot reduces both context and duration while remaining greater than the average shot. In general, location shifts dominate character and time shifts in event segmentation of movies. In addition, over the last 70 years re-establishing shots have become more like the noninitial shots of a scene. Establishing shots have also approached noninitial shot scales, but not their durations. Such results suggest that film form is evolving, perhaps to suit more rapid encoding of narrative events. Copyright © 2014 Cognitive Science Society, Inc.

Rapid fluctuations in ionospheric Faraday rotation angle and 4GHz amplitude scintillation observed at Suva, Fiji

International Nuclear Information System (INIS)

Buonsanto, M.J.; Northcott, R.L.; Wright, R.W.H.

1987-01-01

Observations are reported of rapid fluctuations in Faraday rotation angle (FRA) recorded at 137MHz and amplitude scintillation at 4 GHz. The observations were made at Suva, Fiji Islands (average ionospheric coordinates 17 0 S, 178 0 E) and cover the period September, 1978 through March, 1983. Monthly occurrence of both the FRA fluctuations and the amplitude scintillation are positively correlated with sunspot number and negatively correlated with Ap and hmF2 at Tahiti. No events were seen in the summer months (November, December, and January) and it is suggested that the south to north neutral wind may be responsible for this. Maximum occurrence of both the 137 MHz FRA fluctuations and the 4 GHz scintillation is in April-May and August-September. The more rapid FRA fluctuations, termed here V-type, occur more often in months when the ambient electron density is larger. Most events occur in the pre-midnight sector, as observed elsewhere. Fewer 4 GHz events are observed at later times in the evening, as compared to the 137 MHz FRA fluctuations

Internal validation of the RapidHIT® ID system.

Science.gov (United States)

Wiley, Rachel; Sage, Kelly; LaRue, Bobby; Budowle, Bruce

2017-11-01

Traditionally, forensic DNA analysis has required highly skilled forensic geneticists in a dedicated laboratory to generate short tandem repeat (STR) profiles. STR profiles are routinely used either to associate or exclude potential donors of forensic biological evidence. The typing of forensic reference samples has become more demanding, especially with the requirement in some jurisdictions to DNA profile arrestees. The Rapid DNA (RDNA) platform, the RapidHIT ® ID (IntegenX ® , Pleasanton, CA), is a fully automated system capable of processing reference samples in approximately 90min with minimal human intervention. Thus, the RapidHIT ID instrument can be deployed to non-laboratory environments (e.g., booking stations) and run by trained atypical personnel such as law enforcement. In order to implement the RapidHIT ID platform, validation studies are needed to define the performance and limitations of the system. Internal validation studies were undertaken with four early-production RapidHIT ID units. Reliable and concordant STR profiles were obtained from reference buccal swabs. Throughout the study, no contamination was observed. The overall first-pass success rate with an "expert-like system" was 72%, which is comparable to another current RDNA platform commercially available. The system's second-pass success rate (involving manual interpretation on first-pass inconclusive results) increased to 90%. Inhibitors (i.e., coffee, smoking tobacco, and chewing tobacco) did not appear to affect typing by the instrument system; however, substrate (i.e., swab type) did impact typing success. Additionally, one desirable feature not available with other Rapid systems is that in the event of a system failed run, a swab can be recovered and subsequently re-analyzed in a new sample cartridge. Therefore, rarely should additional sampling or swab consumption be necessary. The RapidHIT ID system is a robust and reliable tool capable of generating complete STR profiles within

Environmental Consequences of Rapid Urbanization in Zhejiang Province, East China

Directory of Open Access Journals (Sweden)

Xuchao Yang

2014-07-01

Full Text Available Since reforms carried out in the late 1970s, China has experienced unprecedented rates of urban growth. Remote sensing data and surface observational data are used to investigate the urbanization process and related environmental consequences, focusing on extreme heat events and air pollution, in Zhejiang Province (ZJP, East China. Examination of satellite-measured nighttime light data indicates rapid urbanization in ZJP during the past decade, initially forming three urban clusters. With rapid urban sprawl, a significant Urban Heat Island (UHI effect has emerged. During extreme heat events in summer, the UHI effect significantly exacerbates nocturnal heat stress in highly urbanized areas. Taking a long-term view, urbanization also causes additional hot days and hot degree days in urban areas. Urbanization also imposes a heavy burden on local and regional air quality in ZJP. Degraded visibility and an increase in haze days are observed at most meteorological stations, especially in the three urban clusters. The results show that urbanization has led to serious environmental problems in ZJP, not only on the city scale, but also on the regional scale. Maintaining a balance between the continuing process of urbanization and environmental sustainability is a major issue facing the local government.

Middle Holocene rapid environmental changes and human adaptation in Greece

Science.gov (United States)

Lespez, Laurent; Glais, Arthur; Lopez-Saez, José-Antonio; Le Drezen, Yann; Tsirtsoni, Zoï; Davidson, Robert; Biree, Laetitia; Malamidou, Dimitra

2016-03-01

Numerous researchers discuss of the collapse of civilizations in response to abrupt climate change in the Mediterranean region. The period between 6500 and 5000 cal yr BP is one of the least studied episodes of rapid climate change at the end of the Late Neolithic. This period is characterized by a dramatic decline in settlement and a cultural break in the Balkans. High-resolution paleoenvironmental proxy data obtained in the Lower Angitis Valley enables an examination of the societal responses to rapid climatic change in Greece. Development of a lasting fluvio-lacustrine environment followed by enhanced fluvial activity is evident from 6000 cal yr BP. Paleoecological data show a succession of dry events at 5800-5700, 5450 and 5000-4900 cal yr BP. These events correspond to incursion of cold air masses to the eastern Mediterranean, confirming the climatic instability of the middle Holocene climate transition. Two periods with farming and pastural activities (6300-5600 and 5100-4700 cal BP) are evident. The intervening period is marked by environmental changes, but the continuous occurrence of anthropogenic taxa suggests the persistence of human activities despite the absence of archaeological evidence. The environmental factors alone were not sufficient to trigger the observed societal changes.

Livestock disease threats associated with intensification of pastoral dairy farming.

Science.gov (United States)

Lean, Ij; Westwood, Ct; Playford, Mc

2008-12-01

This paper provides an overview of the changes in the pasture-based dairy systems of New Zealand and Australia that may influence the health of cattle. There are relatively few available data that can be used to quantify the effects of increased intensification of milk production on the health of cattle. There is evidence that increased production increases the risk of mastitis and culling for udder health. Increased risks of mastitis with treatment with somatotropin support these findings; however, the risk of mastitis may decrease with increased milking frequency. Larger herds with greater stocking density should increase the risk for infectious disease, but evidence to support this contention is sparse. Very intensive grazing patterns associated with higher grass yields achieved using better cultivars and greater use of fertilisers favour nematode parasites. There is some evidence of anthelmintic resistance in both nematodes and liver fluke. Veterinarians will need to be aware of the potential for these to reduce the productivity of cattle. There have been benefits of improved nutrition on the efficiency of energy use for dairy production. Diseases such as bloat and ketosis appear to be of lower prevalence. It also appears that mineral nutrition of pasture-fed cattle is being better addressed, with gains in the control of milk fever, hypomagnesaemia and trace-element deficiencies. However, acidosis is a condition with a high point prevalence in pasture-based dairy systems where cows are fed supplements; one study in Australia found a point prevalence of approximately 11% of cows with acidosis. There is evidence from this study that the neutral detergent fibre (NDF) in pasture-based diets may need to be higher than 30% of the diet to maintain rumen stability. Laminitis and acidosis are different conditions with a similar pathogenesis, specifically highly fermentable diets. The prevalence of lameness was 28% in herds in Australia, suggesting that this condition

Selecting native perennial plants for ecological intensification in Mediterranean greenhouse horticulture.

Science.gov (United States)

Rodríguez, E; González, M; Paredes, D; Campos, M; Benítez, E

2017-12-04

Natural control by predators and parasitoids provides an important and often unnoticed ecosystem service to agricultural landscapes by reducing pest populations in crops. The current model of horticultural intensification in south-eastern Spain produces high yields but has also resulted in a landscape almost completely covered by plastic. Promoting natural areas among greenhouses could enhance biodiversity, by being beneficial insects, and reduce pest pressure outdoors. The first step is to ascertain how pests and their natural enemies (NEs) use Mediterranean vegetation for selecting the best plants for pest suppression outdoors. The abundance of the two major horticultural pests, the tobacco whitefly, Bemisia tabaci, and the western flower thrips, Frankliniella occidentalis, together with their NEs, were assayed in 22 flowering perennial plants, which were newly planted in an experimental field surrounded by greenhouses. Eight plant species were identified as the most critical species for sustaining pest populations outdoors. A set of five plant species supported a medium level of pests, and another set of ten plant species supported the lowest level of both pests. Tobacco whitefly occurred in a few plants species, whereas western flower thrips occurred on almost all the plant species studied, and was favoured by the presence of flowers in perennial plants. The results suggest that plant diversity may provide relatively few acceptable host plants for tobacco whitefly than for western flower thrips. NEs were generally collected in plants that also supported abundance of pests, indicating that host/prey availability, more than food resources from flowers, was a stronger predictor of NE abundance in perennial plants. Field trials using the plants with the lowest host acceptance by pests are needed in order to ascertain whether pest abundance outdoors is reduced.

Stable carbon isotope response to oceanic anoxic events

International Nuclear Information System (INIS)

Hu Xiumian; Wang Chengshan; Li Xianghui

2001-01-01

Based on discussion of isotope compositions and fractionation of marine carbonate and organic carbon, the author studies the relationship between oceanic anoxic events and changes in the carbon isotope fractionation of both carbonate and organic matter. During the oceanic anoxic events, a great number of organisms were rapidly buried, which caused a kind of anoxic conditions by their decomposition consuming dissolved oxygen. Since 12 C-rich organism preserved, atmosphere-ocean system will enrich relatively of 13 C. As a result, simultaneous marine carbonate will record the positive excursion of carbon isotope. There is a distinctive δ 13 C excursion during oceanic anoxic events in the world throughout the geological time. In the Cenomanian-Turonian anoxic event. this positive excursion arrived at ∼0.2% of marine carbonate and at ∼0.4% of organic matter, respectively. Variations in the carbon isotopic compositions of marine carbonate and organic carbon record the changes in the fraction of organic carbon buried throughout the geological time and may provide clues to the changes in rates of weathering and burial of organic carbon. This will provide a possibility of interpreting not only the changes in the global carbon cycle throughout the geological time, but also that in atmospheric p CO 2

Methods and Model Dependency of Extreme Event Attribution: The 2015 European Drought

Science.gov (United States)

Hauser, Mathias; Gudmundsson, Lukas; Orth, René; Jézéquel, Aglaé; Haustein, Karsten; Vautard, Robert; van Oldenborgh, Geert J.; Wilcox, Laura; Seneviratne, Sonia I.

2017-10-01

Science on the role of anthropogenic influence on extreme weather events, such as heatwaves or droughts, has evolved rapidly in the past years. The approach of "event attribution" compares the occurrence-probability of an event in the present, factual climate with its probability in a hypothetical, counterfactual climate without human-induced climate change. Several methods can be used for event attribution, based on climate model simulations and observations, and usually researchers only assess a subset of methods and data sources. Here, we explore the role of methodological choices for the attribution of the 2015 meteorological summer drought in Europe. We present contradicting conclusions on the relevance of human influence as a function of the chosen data source and event attribution methodology. Assessments using the maximum number of models and counterfactual climates with pre-industrial greenhouse gas concentrations point to an enhanced drought risk in Europe. However, other evaluations show contradictory evidence. These results highlight the need for a multi-model and multi-method framework in event attribution research, especially for events with a low signal-to-noise ratio and high model dependency such as regional droughts.

Rapid Response Fault Drilling Past, Present, and Future

Directory of Open Access Journals (Sweden)

Demian M. Saffer

2009-09-01

Full Text Available New information about large earthquakes can be acquired by drilling into the fault zone quickly following a large seismic event. Specifically, we can learn about the levels of friction and strength of the fault which determine the dynamic rupture, monitor the healing process of the fault, record the stress changes that trigger aftershocks and capture important physical and chemical properties of the fault that control the rupture process. These scientific and associated technical issues were the focus of a three-day workshop on Rapid Response Fault Drilling: Past, Present, and Future, sponsored by the International Continental Scientific Drilling Program (ICDP and the Southern California Earthquake Center (SCEC. The meeting drewtogether forty-four scientists representing ten countries in Tokyo, Japan during November 2008. The group discussed the scientific problems and how they could be addressed through rapid response drilling. Focused talks presented previous work on drilling after large earthquakes and in fault zones in general, as well as the state of the art of experimental techniques and measurement strategies. Detailed discussion weighed the tradeoffs between rapid drilling andthe ability to satisfy a diverse range of scientific objectives. Plausible drilling sites and scenarios were evaluated. This is a shortened summary of the workshop report that discusses key scientific questions, measurement strategies, and recommendations. This report can provide a starting point for quickly mobilizing a drilling program following future large earthquakes. The full report can be seen at http://www.pmc.ucsc.edu/~rapid/.

Rapid response teams: qualitative analysis of their effectiveness.

Science.gov (United States)

Leach, Linda Searle; Mayo, Ann M

2013-05-01

Multidisciplinary rapid response teams focus on patients' emergent needs and manage critical situations to prevent avoidable deaths. Although research has focused primarily on outcomes, studies of the actual team effectiveness within the teams from multiple perspectives have been limited. To describe effectiveness of rapid response teams in a large teaching hospital in California that had been using such teams for 5 years. The grounded-theory method was used to discover if substantive theory might emerge from interview and/or observational data. Purposeful sampling was used to conduct in-person semistructured interviews with 17 key informants. Convenience sampling was used for the 9 observed events that involved a rapid response team. Analysis involved use of a concept or indicator model to generate empirical results from the data. Data were coded, compared, and contrasted, and, when appropriate, relationships between concepts were formed. Results Dimensions of effective team performance included the concepts of organizational culture, team structure, expertise, communication, and teamwork. Professionals involved reported that rapid response teams functioned well in managing patients at risk or in crisis; however, unique challenges were identified. Teams were loosely coupled because of the inconsistency of team members from day to day. Team members had little opportunity to develop relationships or team skills. The need for team training may be greater than that among teams that work together regularly under less time pressure to perform. Communication between team members and managing a crisis were critical aspects of an effective response team.

Mapping the Recent US Hurricanes Triggered Flood Events in Near Real Time

Science.gov (United States)

Shen, X.; Lazin, R.; Anagnostou, E. N.; Wanik, D. W.; Brakenridge, G. R.

2017-12-01

Synthetic Aperture Radar (SAR) observations is the only reliable remote sensing data source to map flood inundation during severe weather events. Unfortunately, since state-of-art data processing algorithms cannot meet the automation and quality standard of a near-real-time (NRT) system, quality controlled inundation mapping by SAR currently depends heavily on manual processing, which limits our capability to quickly issue flood inundation maps at global scale. Specifically, most SAR-based inundation mapping algorithms are not fully automated, while those that are automated exhibit severe over- and/or under-detection errors that limit their potential. These detection errors are primarily caused by the strong overlap among the SAR backscattering probability density functions (PDF) of different land cover types. In this study, we tested a newly developed NRT SAR-based inundation mapping system, named Radar Produced Inundation Diary (RAPID), using Sentinel-1 dual polarized SAR data over recent flood events caused by Hurricanes Harvey, Irma, and Maria (2017). The system consists of 1) self-optimized multi-threshold classification, 2) over-detection removal using land-cover information and change detection, 3) under-detection compensation, and 4) machine-learning based correction. Algorithm details are introduced in another poster, H53J-1603. Good agreements were obtained by comparing the result from RAPID with visual interpretation of SAR images and manual processing from Dartmouth Flood Observatory (DFO) (See Figure 1). Specifically, the over- and under-detections that is typically noted in automated methods is significantly reduced to negligible levels. This performance indicates that RAPID can address the automation and accuracy issues of current state-of-art algorithms and has the potential to apply operationally on a number of satellite SAR missions, such as SWOT, ALOS, Sentinel etc. RAPID data can support many applications such as rapid assessment of damage

Event Index - a LHCb Event Search System

CERN Document Server

INSPIRE-00392208; Kazeev, Nikita; Redkin, Artem

2015-12-23

LHC experiments generate up to $10^{12}$ events per year. This paper describes Event Index - an event search system. Event Index's primary function is quickly selecting subsets of events from a combination of conditions, such as the estimated decay channel or stripping lines output. Event Index is essentially Apache Lucene optimized for read-only indexes distributed over independent shards on independent nodes.

Event Patterns Extracted from Transverse Momentum and Rapidity Spectra of Z Bosons and Quarkonium States Produced in pp and Pb-Pb Collisions at LHC

Directory of Open Access Journals (Sweden)

Ya-Hui Chen

2016-01-01

Full Text Available Transverse momentum (pT and rapidity (y spectra of Z bosons and quarkonium states (some charmonium cc¯ mesons such as J/ψ and ψ(2S and some bottomonium bb¯ mesons such as Υ(1S, Υ(2S, and Υ(3S produced in proton-proton (pp and lead-lead (Pb-Pb collisions at the large hadron collider (LHC are uniformly described by a hybrid model of two-component Erlang distribution for pT spectrum and two-component Gaussian distribution for y spectrum. The former distribution results from a multisource thermal model, and the latter one results from the revised Landau hydrodynamic model. The modelling results are in agreement with the experimental data measured in pp collisions at center-of-mass energies s=2.76 and 7 TeV and in Pb-Pb collisions at center-of-mass energy per nucleon pair sNN=2.76 TeV. Based on the parameter values extracted from pT and y spectra, the event patterns (particle scatter plots in two-dimensional pT-y space and in three-dimensional velocity space are obtained.

Event segmentation ability uniquely predicts event memory.

Science.gov (United States)

Sargent, Jesse Q; Zacks, Jeffrey M; Hambrick, David Z; Zacks, Rose T; Kurby, Christopher A; Bailey, Heather R; Eisenberg, Michelle L; Beck, Taylor M

2013-11-01

Memory for everyday events plays a central role in tasks of daily living, autobiographical memory, and planning. Event memory depends in part on segmenting ongoing activity into meaningful units. This study examined the relationship between event segmentation and memory in a lifespan sample to answer the following question: Is the ability to segment activity into meaningful events a unique predictor of subsequent memory, or is the relationship between event perception and memory accounted for by general cognitive abilities? Two hundred and eight adults ranging from 20 to 79years old segmented movies of everyday events and attempted to remember the events afterwards. They also completed psychometric ability tests and tests measuring script knowledge for everyday events. Event segmentation and script knowledge both explained unique variance in event memory above and beyond the psychometric measures, and did so as strongly in older as in younger adults. These results suggest that event segmentation is a basic cognitive mechanism, important for memory across the lifespan. Copyright © 2013 Elsevier B.V. All rights reserved.

Study of the underlying event at forward rapidity in pp collisions at $\\sqrt{s}$ = 0.9, 2.76, and 7 TeV

CERN Document Server

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Szleper, Michal; Wrochna, Grzegorz; Zalewski, Piotr; Brona, Grzegorz; Bunkowski, Karol; Cwiok, Mikolaj; Dominik, Wojciech; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Misiura, Maciej; Wolszczak, Weronika; Almeida, Nuno; Bargassa, Pedrame; David Tinoco Mendes, Andre; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Seixas, Joao; Varela, Joao; Vischia, Pietro; Belotelov, Ivan; Bunin, Pavel; Gavrilenko, Mikhail; Golutvin, Igor; Gorbunov, Ilya; Kamenev, Alexey; Karjavin, Vladimir; Kozlov, Guennady; Lanev, Alexander; Malakhov, Alexander; Moisenz, Petr; Palichik, Vladimir; Perelygin, Victor; Shmatov, Sergey; Smirnov, Vitaly; Volodko, Anton; Zarubin, Anatoli; Evstyukhin, Sergey; Golovtsov, Victor; Ivanov, Yury; Kim, Victor; Levchenko, Petr; Murzin, Victor; Oreshkin, Vadim; Smirnov, Igor; Sulimov, Valentin; Uvarov, Lev; Vavilov, Sergey; Vorobyev, Alexey; Vorobyev, Andrey; Andreev, Yuri; Dermenev, Alexander; Gninenko, Sergei; Golubev, Nikolai; Kirsanov, Mikhail; Krasnikov, Nikolai; Matveev, Viktor; Pashenkov, Anatoli; Tlisov, Danila; Toropin, Alexander; Epshteyn, Vladimir; Erofeeva, Maria; Gavrilov, Vladimir; Kossov, Mikhail; Lychkovskaya, Natalia; Popov, Vladimir; Safronov, Grigory; Semenov, Sergey; Shreyber, Irina; Stolin, Viatcheslav; Vlasov, Evgueni; Zhokin, Alexander; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Leonidov, Andrey; Mesyats, Gennady; Rusakov, Sergey V; Vinogradov, Alexey; Belyaev, Andrey; Bogdanova, Galina; Boos, Edouard; Khein, Lev; Klyukhin, Vyacheslav; Kodolova, Olga; Lokhtin, Igor; Lukina, Olga; Markina, Anastasia; Obraztsov, Stepan; Perfilov, Maxim; Petrushanko, Sergey; Popov, Andrey; Proskuryakov, Alexander; Sarycheva, Ludmila; Savrin, Viktor; Volkov, Vladimir; Azhgirey, Igor; Bayshev, Igor; Bitioukov, Sergei; Grishin, Viatcheslav; Kachanov, Vassili; Konstantinov, Dmitri; Krychkine, Victor; Petrov, Vladimir; Ryutin, Roman; Sobol, Andrei; Tourtchanovitch, Leonid; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Djordjevic, Milos; Ekmedzic, Marko; Krpic, Dragomir; Milosevic, Jovan; Aguilar-Benitez, Manuel; Alcaraz Maestre, Juan; Arce, Pedro; Battilana, Carlo; Calvo, Enrique; Cerrada, Marcos; Chamizo Llatas, Maria; Colino, Nicanor; De La Cruz, Begona; Delgado Peris, Antonio; Domínguez Vázquez, Daniel; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Ferrando, Antonio; Flix, Jose; Fouz, Maria Cruz; Garcia-Abia, Pablo; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M; Josa, Maria Isabel; Merino, Gonzalo; Puerta Pelayo, Jesus; Quintario Olmeda, Adrián; Redondo, Ignacio; Romero, Luciano; Santaolalla, Javier; Senghi Soares, Mara; Willmott, Carlos; Albajar, Carmen; Codispoti, Giuseppe; de Trocóniz, Jorge F; Brun, Hugues; Cuevas, Javier; Fernandez Menendez, Javier; Folgueras, Santiago; Gonzalez Caballero, Isidro; Lloret Iglesias, Lara; Piedra Gomez, Jonatan; Brochero Cifuentes, Javier Andres; Cabrillo, Iban Jose; Calderon, Alicia; Chuang, Shan-Huei; Duarte Campderros, Jordi; Felcini, Marta; Fernandez, Marcos; Gomez, Gervasio; Gonzalez Sanchez, Javier; Graziano, Alberto; Jorda, Clara; Lopez Virto, Amparo; Marco, Jesus; Marco, Rafael; Martinez Rivero, Celso; Matorras, Francisco; Munoz Sanchez, Francisca Javiela; Rodrigo, Teresa; Rodríguez-Marrero, Ana Yaiza; Ruiz-Jimeno, Alberto; Scodellaro, Luca; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Auffray, Etiennette; Auzinger, Georg; Bachtis, Michail; Baillon, Paul; Ball, Austin; Barney, David; Bendavid, Joshua; Benitez, Jose F; Bernet, Colin; Bianchi, Giovanni; Bloch, Philippe; Bocci, Andrea; Bonato, Alessio; Botta, Cristina; Breuker, Horst; Camporesi, Tiziano; Cerminara, Gianluca; Christiansen, Tim; Coarasa Perez, Jose Antonio; D'Enterria, David; Dabrowski, Anne; De Roeck, Albert; De Visscher, Simon; Di Guida, Salvatore; Dobson, Marc; Dupont-Sagorin, Niels; Elliott-Peisert, Anna; Eugster, Jürg; Frisch, Benjamin; Funk, Wolfgang; Georgiou, Georgios; Giffels, Manuel; Gigi, Dominique; Gill, Karl; Giordano, Domenico; Girone, Maria; Giunta, Marina; Glege, Frank; Gomez-Reino Garrido, Robert; Govoni, Pietro; Gowdy, Stephen; Guida, Roberto; Hammer, Josef; Hansen, Magnus; Harris, Philip; Hartl, Christian; Harvey, John; Hegner, Benedikt; Hinzmann, Andreas; Innocente, Vincenzo; Janot, Patrick; Kaadze, Ketino; Karavakis, Edward; Kousouris, Konstantinos; Krajczar, Krisztian; Lecoq, Paul; Lee, Yen-Jie; Lenzi, Piergiulio; Lourenco, Carlos; Magini, Nicolo; Maki, Tuula; Malberti, Martina; Malgeri, Luca; Mannelli, Marcello; Masetti, Lorenzo; Meijers, Frans; Mersi, Stefano; Meschi, Emilio; Moser, Roland; Mulders, Martijn; Musella, Pasquale; Nesvold, Erik; Orsini, Luciano; Palencia Cortezon, Enrique; Perez, Emmanuelle; Perrozzi, Luca; Petrilli, Achille; Pfeiffer, Andreas; Pierini, Maurizio; Pimiä, Martti; Piparo, Danilo; Polese, Giovanni; Quertenmont, Loic; Racz, Attila; Reece, William; Rodrigues Antunes, Joao; Rolandi, Gigi; Rovelli, Chiara; Rovere, Marco; Sakulin, Hannes; Santanastasio, Francesco; Schäfer, Christoph; Schwick, Christoph; Segoni, Ilaria; Sekmen, Sezen; Sharma, Archana; Siegrist, Patrice; Silva, Pedro; Simon, Michal; Sphicas, Paraskevas; Spiga, Daniele; Tsirou, Andromachi; Veres, Gabor Istvan; Vlimant, Jean-Roch; Wöhri, Hermine Katharina; Worm, Steven; Zeuner, Wolfram Dietrich; Bertl, Willi; Deiters, Konrad; Erdmann, Wolfram; Gabathuler, Kurt; Horisberger, Roland; Ingram, Quentin; Kaestli, Hans-Christian; König, Stefan; Kotlinski, Danek; Langenegger, Urs; Meier, Frank; Renker, Dieter; Rohe, Tilman; Bachmair, Felix; Bäni, Lukas; Bortignon, Pierluigi; Buchmann, Marco-Andrea; Casal, Bruno; Chanon, Nicolas; Deisher, Amanda; Dissertori, Günther; Dittmar, Michael; Donegà, Mauro; Dünser, Marc; Eller, Philipp; Freudenreich, Klaus; Grab, Christoph; Hits, Dmitry; Lecomte, Pierre; Lustermann, Werner; Marini, Andrea Carlo; Martinez Ruiz del Arbol, Pablo; Mohr, Niklas; Moortgat, Filip; Nägeli, Christoph; Nef, Pascal; Nessi-Tedaldi, Francesca; Pandolfi, Francesco; Pape, Luc; Pauss, Felicitas; Peruzzi, Marco; Ronga, Frederic Jean; Rossini, Marco; Sala, Leonardo; Sanchez, Ann - Karin; Starodumov, Andrei; Stieger, Benjamin; Takahashi, Maiko; Tauscher, Ludwig; Thea, Alessandro; Theofilatos, Konstantinos; Treille, Daniel; Urscheler, Christina; Wallny, Rainer; Weber, Hannsjoerg Artur; Wehrli, Lukas; Amsler, Claude; Chiochia, Vincenzo; Favaro, Carlotta; Ivova Rikova, Mirena; Kilminster, Benjamin; Millan Mejias, Barbara; Otiougova, Polina; Robmann, Peter; Snoek, Hella; Tupputi, Salvatore; Verzetti, Mauro; Cardaci, Marco; Chang, Yuan-Hann; Chen, Kuan-Hsin; Ferro, Cristina; Kuo, Chia-Ming; Li, Syue-Wei; Lin, Willis; Lu, Yun-Ju; Singh, Anil; Volpe, Roberta; Yu, Shin-Shan; Bartalini, Paolo; Chang, Paoti; Chang, You-Hao; Chang, Yu-Wei; Chao, Yuan; Chen, Kai-Feng; Dietz, Charles; Grundler, Ulysses; Hou, George Wei-Shu; Hsiung, Yee; Kao, Kai-Yi; Lei, Yeong-Jyi; Lu, Rong-Shyang; Majumder, Devdatta; Petrakou, Eleni; Shi, Xin; Shiu, Jing-Ge; Tzeng, Yeng-Ming; Wan, Xia; Wang, Minzu; Asavapibhop, Burin; Simili, Emanuele; Srimanobhas, Norraphat; Suwonjandee, Narumon; Adiguzel, Aytul; Bakirci, Mustafa Numan; Cerci, Salim; Dozen, Candan; Dumanoglu, Isa; Eskut, Eda; Girgis, Semiray; Gokbulut, Gul; Gurpinar, Emine; Hos, Ilknur; Kangal, Evrim Ersin; Karaman, Turker; Karapinar, Guler; Kayis Topaksu, Aysel; Onengut, Gulsen; Ozdemir, Kadri; Ozturk, Sertac; Polatoz, Ayse; Sogut, Kenan; Sunar Cerci, Deniz; Tali, Bayram; Topakli, Huseyin; Vergili, Mehmet; Akin, Ilina Vasileva; Aliev, Takhmasib; Bilin, Bugra; Bilmis, Selcuk; Deniz, Muhammed; Gamsizkan, Halil; Guler, Ali Murat; Ocalan, Kadir; Ozpineci, Altug; Serin, Meltem; Sever, Ramazan; Surat, Ugur Emrah; Yalvac, Metin; Zeyrek, Mehmet; Gülmez, Erhan; Isildak, Bora; Kaya, Mithat; Kaya, Ozlem; Ozkorucuklu, Suat; Sonmez, Nasuf; Bahtiyar, Hüseyin; Barlas, Esra; Cankocak, Kerem; Günaydin, Yusuf Oguzhan; Vardarli, Fuat Ilkehan; Yücel, Mete; Levchuk, Leonid; Brooke, James John; Clement, Emyr; Cussans, David; Flacher, Henning; Frazier, Robert; Goldstein, Joel; Grimes, Mark; Heath, Greg P; Heath, Helen F; Kreczko, Lukasz; Metson, Simon; Newbold, Dave M; Nirunpong, Kachanon; Poll, Anthony; Senkin, Sergey; Smith, Vincent J; Williams, Thomas; Basso, Lorenzo; Bell, Ken W; Belyaev, Alexander; Brew, Christopher; Brown, Robert M; Cockerill, David JA; Coughlan, John A; Harder, Kristian; Harper, Sam; Jackson, James; Kennedy, Bruce W; Olaiya, Emmanuel; Petyt, David; Radburn-Smith, Benjamin Charles; Shepherd-Themistocleous, Claire; Tomalin, Ian R; Womersley, William John; Bainbridge, Robert; Ball, Gordon; Beuselinck, Raymond; Buchmuller, Oliver; Colling, David; Cripps, Nicholas; Cutajar, Michael; Dauncey, Paul; Davies, Gavin; Della Negra, Michel; Ferguson, William; Fulcher, Jonathan; Futyan, David; Gilbert, Andrew; Guneratne Bryer, Arlo; Hall, Geoffrey; Hatherell, Zoe; Hays, Jonathan; Iles, Gregory; Jarvis, Martyn; Karapostoli, Georgia; Kenzie, Matthew; Lyons, Louis; Magnan, Anne-Marie; Marrouche, Jad; Mathias, Bryn; Nandi, Robin; Nash, Jordan; Nikitenko, Alexander; Pela, Joao; Pesaresi, Mark; Petridis, Konstantinos; Pioppi, Michele; Raymond, David Mark; Rogerson, Samuel; Rose, Andrew; Seez, Christopher; Sharp, Peter; Sparrow, Alex; Stoye, Markus; Tapper, Alexander; Vazquez Acosta, Monica; Virdee, Tejinder; Wakefield, Stuart; Wardle, Nicholas; Whyntie, Tom; Chadwick, Matthew; Cole, Joanne; Hobson, Peter R; Khan, Akram; Kyberd, Paul; Leggat, Duncan; Leslie, Dawn; Martin, William; Reid, Ivan; Symonds, Philip; Teodorescu, Liliana; Turner, Mark; Hatakeyama, Kenichi; Liu, Hongxuan; Scarborough, Tara; Charaf, Otman; Cooper, Seth; Henderson, Conor; Rumerio, Paolo; Avetisyan, Aram; Bose, Tulika; Fantasia, Cory; Heister, Arno; Lawson, Philip; Lazic, Dragoslav; Rohlf, James; Sperka, David; St John, Jason; Sulak, Lawrence; Alimena, Juliette; Bhattacharya, Saptaparna; Christopher, Grant; Cutts, David; Demiragli, Zeynep; Ferapontov, Alexey; Garabedian, Alex; Heintz, Ulrich; Jabeen, Shabnam; Kukartsev, Gennadiy; Laird, Edward; Landsberg, Greg; Luk, Michael; Narain, Meenakshi; Segala, Michael; Sinthuprasith, Tutanon; Speer, Thomas; Breedon, Richard; Breto, Guillermo; Calderon De La Barca Sanchez, Manuel; Caulfield, Matthew; Chauhan, Sushil; Chertok, Maxwell; Conway, John; Conway, Rylan; Cox, Peter Timothy; Dolen, James; Erbacher, Robin; Gardner, Michael; Houtz, Rachel; Ko, Winston; Kopecky, Alexandra; Lander, Richard; Mall, Orpheus; Miceli, Tia; Nelson, Randy; Pellett, Dave; Ricci-Tam, Francesca; Rutherford, Britney; Searle, Matthew; Smith, John; Squires, Michael; Tripathi, Mani; Vasquez Sierra, Ricardo; Yohay, Rachel; Andreev, Valeri; Cline, David; Cousins, Robert; Duris, Joseph; Erhan, Samim; Everaerts, Pieter; Farrell, Chris; Hauser, Jay; Ignatenko, Mikhail; Jarvis, Chad; Rakness, Gregory; Schlein, Peter; Traczyk, Piotr; Valuev, Vyacheslav; Weber, Matthias; Babb, John; Clare, Robert; Dinardo, Mauro Emanuele; Ellison, John Anthony; Gary, J William; Giordano, Ferdinando; Hanson, Gail; Liu, Hongliang; Long, Owen Rosser; Luthra, Arun; Nguyen, Harold; Paramesvaran, Sudarshan; Sturdy, Jared; Sumowidagdo, Suharyo; Wilken, Rachel; Wimpenny, Stephen; Andrews, Warren; Branson, James G; Cerati, Giuseppe Benedetto; Cittolin, Sergio; Evans, David; Holzner, André; Kelley, Ryan; Lebourgeois, Matthew; Letts, James; Macneill, Ian; Mangano, Boris; Padhi, Sanjay; Palmer, Christopher; Petrucciani, Giovanni; Pieri, Marco; Sani, Matteo; Sharma, Vivek; Simon, Sean; Sudano, Elizabeth; Tadel, Matevz; Tu, Yanjun; Vartak, Adish; Wasserbaech, Steven; Würthwein, Frank; Yagil, Avraham; Yoo, Jaehyeok; Barge, Derek; Bellan, Riccardo; Campagnari, Claudio; D'Alfonso, Mariarosaria; Danielson, Thomas; Flowers, Kristen; Geffert, Paul; George, Christopher; Golf, Frank; Incandela, Joe; Justus, Christopher; Kalavase, Puneeth; Kovalskyi, Dmytro; Krutelyov, Vyacheslav; Lowette, Steven; Magaña Villalba, Ricardo; Mccoll, Nickolas; Pavlunin, Viktor; Ribnik, Jacob; Richman, Jeffrey; Rossin, Roberto; Stuart, David; To, Wing; West, Christopher; Apresyan, Artur; Bornheim, Adolf; Bunn, Julian; Chen, Yi; Di Marco, Emanuele; Duarte, Javier; Gataullin, Marat; Kcira, Dorian; Ma, Yousi; Mott, Alexander; Newman, Harvey B; Rogan, Christopher; Spiropulu, Maria; Timciuc, Vladlen; Veverka, Jan; Wilkinson, Richard; Xie, Si; Yang, Yong; Zhu, Ren-Yuan; Azzolini, Virginia; Calamba, Aristotle; Carroll, Ryan; Ferguson, Thomas; Iiyama, Yutaro; Jang, Dong Wook; Liu, Yueh-Feng; Paulini, Manfred; Vogel, Helmut; Vorobiev, Igor; Cumalat, John Perry; Drell, Brian Robert; Ford, William T; Gaz, Alessandro; Luiggi Lopez, Eduardo; Smith, James; Stenson, Kevin; Ulmer, Keith; Wagner, Stephen Robert; Alexander, James; Chatterjee, Avishek; Eggert, Nicholas; Gibbons, Lawrence Kent; Heltsley, Brian; Hopkins, Walter; Khukhunaishvili, Aleko; Kreis, Benjamin; Mirman, Nathan; Nicolas Kaufman, Gala; Patterson, Juliet Ritchie; Ryd, Anders; Salvati, Emmanuele; Sun, Werner; Teo, Wee Don; Thom, Julia; Thompson, Joshua; Tucker, Jordan; Weng, Yao; Winstrom, Lucas; Wittich, Peter; Winn, Dave; Abdullin, Salavat; Albrow, Michael; Anderson, Jacob; Bauerdick, Lothar AT; Beretvas, Andrew; Berryhill, Jeffrey; Bhat, Pushpalatha C; Burkett, Kevin; Butler, Joel Nathan; Chetluru, Vasundhara; Cheung, Harry; Chlebana, Frank; Cihangir, Selcuk; Elvira, Victor Daniel; Fisk, Ian; Freeman, Jim; Gao, Yanyan; Green, Dan; Gutsche, Oliver; Hanlon, Jim; Harris, Robert M; Hirschauer, James; Hooberman, Benjamin; Jindariani, Sergo; Johnson, Marvin; Joshi, Umesh; Klima, Boaz; Kunori, Shuichi; Kwan, Simon; Leonidopoulos, Christos; Linacre, Jacob; Lincoln, Don; Lipton, Ron; Lykken, Joseph; Maeshima, Kaori; Marraffino, John Michael; Martinez Outschoorn, Verena Ingrid; Maruyama, Sho; Mason, David; McBride, Patricia; Mishra, Kalanand; Mrenna, Stephen; Musienko, Yuri; Newman-Holmes, Catherine; O'Dell, Vivian; Prokofyev, Oleg; Sexton-Kennedy, Elizabeth; Sharma, Seema; Spalding, William J; Spiegel, Leonard; Taylor, Lucas; Tkaczyk, Slawek; Tran, Nhan Viet; Uplegger, Lorenzo; Vaandering, Eric Wayne; Vidal, Richard; Whitmore, Juliana; Wu, Weimin; Yang, Fan; Yun, Jae Chul; Acosta, Darin; Avery, Paul; Bourilkov, Dimitri; Chen, Mingshui; Cheng, Tongguang; Das, Souvik; De Gruttola, Michele; Di Giovanni, Gian Piero; Dobur, Didar; Drozdetskiy, Alexey; Field, Richard D; Fisher, Matthew; Fu, Yu; Furic, Ivan-Kresimir; Gartner, Joseph; Hugon, Justin; Kim, Bockjoo; Konigsberg, Jacobo; Korytov, Andrey; Kropivnitskaya, Anna; Kypreos, Theodore; Low, Jia Fu; Matchev, Konstantin; Milenovic, Predrag; Mitselmakher, Guenakh; Muniz, Lana; Remington, Ronald; Rinkevicius, Aurelijus; Skhirtladze, Nikoloz; Snowball, Matthew; Yelton, John; Zakaria, Mohammed; Gaultney, Vanessa; Hewamanage, Samantha; Lebolo, Luis Miguel; Linn, Stephan; Markowitz, Pete; Martinez, German; Rodriguez, Jorge Luis; Adams, Todd; Askew, Andrew; Bochenek, Joseph; Chen, Jie; Diamond, Brendan; Gleyzer, Sergei V; Haas, Jeff; Hagopian, Sharon; Hagopian, Vasken; Jenkins, Merrill; Johnson, Kurtis F; Prosper, Harrison; Veeraraghavan, Venkatesh; Weinberg, Marc; Baarmand, Marc M; Dorney, Brian; Hohlmann, Marcus; Kalakhety, Himali; Vodopiyanov, Igor; Yumiceva, Francisco; Adams, Mark Raymond; Apanasevich, Leonard; Bai, Yuting; Bazterra, Victor Eduardo; Betts, Russell Richard; Bucinskaite, Inga; Callner, Jeremy; Cavanaugh, Richard; Evdokimov, Olga; Gauthier, Lucie; Gerber, Cecilia Elena; Hofman, David Jonathan; Khalatyan, Samvel; Lacroix, Florent; O'Brien, Christine; Silkworth, Christopher; Strom, Derek; Turner, Paul; Varelas, Nikos; Akgun, Ugur; Albayrak, Elif Asli; Bilki, Burak; Clarida, Warren; Dilsiz, Kamuran; Duru, Firdevs; Griffiths, Scott; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mestvirishvili, Alexi; Moeller, Anthony; Nachtman, Jane; Newsom, Charles Ray; Norbeck, Edwin; Ogul, Hasan; Onel, Yasar; Ozok, Ferhat; Sen, Sercan; Tan, Ping; Tiras, Emrah; Wetzel, James; Yetkin, Taylan; Yi, Kai; Barnett, Bruce Arnold; Blumenfeld, Barry; Bolognesi, Sara; Fehling, David; Giurgiu, Gavril; Gritsan, Andrei; Guo, Zijin; Hu, Guofan; Maksimovic, Petar; Swartz, Morris; Whitbeck, Andrew; Baringer, Philip; Bean, Alice; Benelli, Gabriele; Kenny III, Raymond Patrick; Murray, Michael; Noonan, Daniel; Sanders, Stephen; Stringer, Robert; Tinti, Gemma; Wood, Jeffrey Scott; Barfuss, Anne-Fleur; Bolton, Tim; Chakaberia, Irakli; Ivanov, Andrew; Khalil, Sadia; Makouski, Mikhail; Maravin, Yurii; Shrestha, Shruti; Svintradze, Irakli; Gronberg, Jeffrey; Lange, David; Rebassoo, Finn; Wright, Douglas; Baden, Drew; Calvert, Brian; Eno, Sarah Catherine; Gomez, Jaime; Hadley, Nicholas John; Kellogg, Richard G; Kirn, Malina; Kolberg, Ted; Lu, Ying; Marionneau, Matthieu; Mignerey, Alice; Pedro, Kevin; Peterman, Alison; Skuja, Andris; Temple, Jeffrey; Tonjes, Marguerite; Tonwar, Suresh C; Apyan, Aram; Bauer, Gerry; Busza, Wit; Butz, Erik; Cali, Ivan Amos; Chan, Matthew; Dutta, Valentina; Gomez Ceballos, Guillelmo; Goncharov, Maxim; Kim, Yongsun; Klute, Markus; Levin, Andrew; Luckey, Paul David; Ma, Teng; Nahn, Steve; Paus, Christoph; Ralph, Duncan; Roland, Christof; Roland, Gunther; Stephans, George; Stöckli, Fabian; Sumorok, Konstanty; Sung, Kevin; Velicanu, Dragos; Wenger, Edward Allen; Wolf, Roger; Wyslouch, Bolek; Yang, Mingming; Yilmaz, Yetkin; Yoon, Sungho; Zanetti, Marco; Zhukova, Victoria; Dahmes, Bryan; De Benedetti, Abraham; Franzoni, Giovanni; Gude, Alexander; Kao, Shih-Chuan; Klapoetke, Kevin; Kubota, Yuichi; Mans, Jeremy; Pastika, Nathaniel; Rusack, Roger; Sasseville, Michael; Singovsky, Alexander; Tambe, Norbert; Turkewitz, Jared; Cremaldi, Lucien Marcus; Kroeger, Rob; Perera, Lalith; Rahmat, Rahmat; Sanders, David A; Avdeeva, Ekaterina; Bloom, Kenneth; Bose, Suvadeep; Claes, Daniel R; Dominguez, Aaron; Eads, Michael; Keller, Jason; Kravchenko, Ilya; Lazo-Flores, Jose; Malik, Sudhir; Snow, Gregory R; Godshalk, Andrew; Iashvili, Ia; Jain, Supriya; Kharchilava, Avto; Kumar, Ashish; Rappoccio, Salvatore; Wan, Zongru; Alverson, George; Barberis, Emanuela; Baumgartel, Darin; Chasco, Matthew; Haley, Joseph; Nash, David; Orimoto, Toyoko; Trocino, Daniele; Wood, Darien; Zhang, Jinzhong; Anastassov, Anton; Hahn, Kristan Allan; Kubik, Andrew; Lusito, Letizia; Mucia, Nicholas; Odell, Nathaniel; Ofierzynski, Radoslaw Adrian; Pollack, Brian; Pozdnyakov, Andrey; Schmitt, Michael Henry; Stoynev, Stoyan; Velasco, Mayda; Won, Steven; Berry, Douglas; Brinkerhoff, Andrew; Chan, Kwok Ming; Hildreth, Michael; Jessop, Colin; Karmgard, Daniel John; Kolb, Jeff; Lannon, Kevin; Luo, Wuming; Lynch, Sean; Marinelli, Nancy; Morse, David Michael; Pearson, Tessa; Planer, Michael; Ruchti, Randy; Slaunwhite, Jason; Valls, Nil; Wayne, Mitchell; Wolf, Matthias; Antonelli, Louis; Bylsma, Ben; Durkin, Lloyd Stanley; Hill, Christopher; Hughes, Richard; Kotov, Khristian; Ling, Ta-Yung; Puigh, Darren; Rodenburg, Marissa; Smith, Geoffrey; Vuosalo, Carl; Williams, Grayson; Winer, Brian L; Berry, Edmund; Elmer, Peter; Halyo, Valerie; Hebda, Philip; Hegeman, Jeroen; Hunt, Adam; Jindal, Pratima; Koay, Sue Ann; Lopes Pegna, David; Lujan, Paul; Marlow, Daniel; Medvedeva, Tatiana; Mooney, Michael; Olsen, James; Piroué, Pierre; Quan, Xiaohang; Raval, Amita; Saka, Halil; Stickland, David; Tully, Christopher; Werner, Jeremy Scott; Zenz, Seth Conrad; Zuranski, Andrzej; Brownson, Eric; Lopez, Angel; Mendez, Hector; Ramirez Vargas, Juan Eduardo; Alagoz, Enver; Barnes, Virgil E; Benedetti, Daniele; Bolla, Gino; Bortoletto, Daniela; De Mattia, Marco; Everett, Adam; Hu, Zhen; Jones, Matthew; Koybasi, Ozhan; Kress, Matthew; Laasanen, Alvin T; Leonardo, Nuno; Maroussov, Vassili; Merkel, Petra; Miller, David Harry; Neumeister, Norbert; Shipsey, Ian; Silvers, David; Svyatkovskiy, Alexey; Vidal Marono, Miguel; Yoo, Hwi Dong; Zablocki, Jakub; Zheng, Yu; Guragain, Samir; Parashar, Neeti; Adair, Antony; Akgun, Bora; Boulahouache, Chaouki; Ecklund, Karl Matthew; Geurts, Frank JM; Li, Wei; Padley, Brian Paul; Redjimi, Radia; Roberts, Jay; Zabel, James; Betchart, Burton; Bodek, Arie; Chung, Yeon Sei; Covarelli, Roberto; de Barbaro, Pawel; Demina, Regina; Eshaq, Yossof; Ferbel, Thomas; Garcia-Bellido, Aran; Goldenzweig, Pablo; Han, Jiyeon; Harel, Amnon; Miner, Daniel Carl; Vishnevskiy, Dmitry; Zielinski, Marek; Bhatti, Anwar; Ciesielski, Robert; Demortier, Luc; Goulianos, Konstantin; Lungu, Gheorghe; Malik, Sarah; Mesropian, Christina; Arora, Sanjay; Barker, Anthony; Chou, John Paul; Contreras-Campana, Christian; Contreras-Campana, Emmanuel; Duggan, Daniel; Ferencek, Dinko; Gershtein, Yuri; Gray, Richard; Halkiadakis, Eva; Hidas, Dean; Lath, Amitabh; Panwalkar, Shruti; Park, Michael; Patel, Rishi; Rekovic, Vladimir; Robles, Jorge; Rose, Keith; Salur, Sevil; Schnetzer, Steve; Seitz, Claudia; Somalwar, Sunil; Stone, Robert; Thomas, Scott; Walker, Matthew; Cerizza, Giordano; Hollingsworth, Matthew; Spanier, Stefan; Yang, Zong-Chang; York, Andrew; Eusebi, Ricardo; Flanagan, Will; Gilmore, Jason; Kamon, Teruki; Khotilovich, Vadim; Montalvo, Roy; Osipenkov, Ilya; Pakhotin, Yuriy; Perloff, Alexx; Roe, Jeffrey; Safonov, Alexei; Sakuma, Tai; Sengupta, Sinjini; Suarez, Indara; Tatarinov, Aysen; Toback, David; Akchurin, Nural; Damgov, Jordan; Dragoiu, Cosmin; Dudero, Phillip Russell; Jeong, Chiyoung; Kovitanggoon, Kittikul; Lee, Sung Won; Libeiro, Terence; Volobouev, Igor; Appelt, Eric; Delannoy, Andrés G; Florez, Carlos; Greene, Senta; Gurrola, Alfredo; Johns, Willard; Kurt, Pelin; Maguire, Charles; Melo, Andrew; Sharma, Monika; Sheldon, Paul; Snook, Benjamin; Tuo, Shengquan; Velkovska, Julia; Arenton, Michael Wayne; Balazs, Michael; Boutle, Sarah; Cox, Bradley; Francis, Brian; Goodell, Joseph; Hirosky, Robert; Ledovskoy, Alexander; Lin, Chuanzhe; Neu, Christopher; Wood, John; Gollapinni, Sowjanya; Harr, Robert; Karchin, Paul Edmund; Kottachchi Kankanamge Don, Chamath; Lamichhane, Pramod; Sakharov, Alexandre; Anderson, Michael; Belknap, Donald; Borrello, Laura; Carlsmith, Duncan; Cepeda, Maria; Dasu, Sridhara; Friis, Evan; Gray, Lindsey; Grogg, Kira Suzanne; Grothe, Monika; Hall-Wilton, Richard; Herndon, Matthew; Hervé, Alain; Klabbers, Pamela; Klukas, Jeffrey; Lanaro, Armando; Lazaridis, Christos; Loveless, Richard; Mohapatra, Ajit; Mozer, Matthias Ulrich; Ojalvo, Isabel; Palmonari, Francesco; Pierro, Giuseppe Antonio; Ross, Ian; Savin, Alexander; Smith, Wesley H; Swanson, Joshua

2013-04-11

The underlying event activity in proton-proton collisions at forward pseudorapidity (-6.6 $\\lt \\eta \\lt$ -5.2) is studied with the CMS detector at the LHC, using a novel observable: the ratio of the forward energy density, dE/d$\\eta$, for events with a charged-particle jet produced at central pseudorapidity (abs(eta[jet]) $\\lt$ 2) to the forward energy density for inclusive events. This forward energy density ratio is measured as a function of the central jet transverse momentum, pt, at three different pp centre-of-mass energies ($\\sqrt{s}$ = 0.9, 2.76, and 7 TeV). In addition, the $\\sqrt{s}$ evolution of the forward energy density is studied in inclusive events and in events with a central jet. The results are compared to those of Monte Carlo event generators for pp collisions and are discussed in terms of the underlying event. Whereas the dependence of the forward energy density ratio on jet pt at each $\\sqrt{s}$ separately can be well reproduced by some models, all models fail to simultaneously describe th...

No evident spatial genetic structuring in the rapidly declining Black-tailed Godwit Limosa limosa limosa in the Netherlands

NARCIS (Netherlands)

Trimbos, Krijn B.; Musters, C. J. M.; Verkuil, Yvonne I.; Kentie, Rosemarie; Piersma, Theunis; de Snoo, Geert R.

With 40% of the European Black-tailed Godwit population breeding in The Netherlands, this country harbours internationally significant numbers of this species. However, ongoing agricultural intensification has resulted in the fragmentation of the population and drastic population declines since

Relational databases for conditions data and event selection in ATLAS

International Nuclear Information System (INIS)

Viegas, F; Hawkings, R; Dimitrov, G

2008-01-01

The ATLAS experiment at LHC will make extensive use of relational databases in both online and offline contexts, running to O(TBytes) per year. Two of the most challenging applications in terms of data volume and access patterns are conditions data, making use of the LHC conditions database, COOL, and the TAG database, that stores summary event quantities allowing a rapid selection of interesting events. Both of these databases are being replicated to regional computing centres using Oracle Streams technology, in collaboration with the LCG 3D project. Database optimisation, performance tests and first user experience with these applications will be described, together with plans for first LHC data-taking and future prospects

Relational databases for conditions data and event selection in ATLAS

Energy Technology Data Exchange (ETDEWEB)

Viegas, F; Hawkings, R; Dimitrov, G [CERN, CH-1211 Geneve 23 (Switzerland)

2008-07-15

The ATLAS experiment at LHC will make extensive use of relational databases in both online and offline contexts, running to O(TBytes) per year. Two of the most challenging applications in terms of data volume and access patterns are conditions data, making use of the LHC conditions database, COOL, and the TAG database, that stores summary event quantities allowing a rapid selection of interesting events. Both of these databases are being replicated to regional computing centres using Oracle Streams technology, in collaboration with the LCG 3D project. Database optimisation, performance tests and first user experience with these applications will be described, together with plans for first LHC data-taking and future prospects.

ERP evidence for rapid hedonic evaluation of logos.

Science.gov (United States)

Handy, Todd C; Smilek, Daniel; Geiger, Lena; Liu, Cindy; Schooler, Jonathan W

2010-01-01

We know that human neurocognitive systems rapidly and implicitly evaluate emotionally charged stimuli. But what about more everyday, frequently encountered kinds of objects, such as computer desktop icons and business logos? Do we rapidly and implicitly evaluate these more prosaic visual images, attitude objects that might only engender a mild sense of liking or disliking, if at all? To address this question, we asked participants to view a set of unfamiliar commercial logos in the context of a target identification task as brain electrical responses to these objects were recorded via event-related potentials (ERPs). Following this task, participants individually identified those logos that were most liked or disliked, allowing us to then compare how ERP responses to logos varied as a function of hedonic evaluation-a procedure decoupling evaluative responses from any normative classification of the logos themselves. In Experiment 1, we found that visuocortical processing manifest a specific bias for disliked logos that emerged within the first 200 msec of stimulus onset. In Experiment 2, we replicated this effect while dissociating normative- and novelty-related influences. Taken together, our results provide direct electrophysiological evidence suggesting that we rapidly and implicitly evaluate commercial branding images at a hedonic level.

"cART intensification by the HIV-1 Tat B clade vaccine: progress to phase III efficacy studies".

Science.gov (United States)

Cafaro, Aurelio; Sgadari, Cecilia; Picconi, Orietta; Tripiciano, Antonella; Moretti, Sonia; Francavilla, Vittorio; Pavone Cossut, Maria Rosaria; Buttò, Stefano; Cozzone, Giovanni; Ensoli, Fabrizio; Monini, Paolo; Ensoli, Barbara

2018-02-01

In spite of its success at suppressing HIV replication, combination antiretroviral therapy (cART) only partially reduces immune dysregulation and loss of immune functions. These cART-unmet needs appear to be due to persistent virus replication and cell-to-cell transmission in reservoirs, and are causes of increased patients' morbidity and mortality. Up to now, therapeutic interventions aimed at cART-intensification by attacking the virus reservoir have failed. Areas covered: We briefly review the rationale and clinical development of Tat therapeutic vaccine in cART-treated subjects in Italy and South Africa (SA). Vaccination with clade-B Tat induced cross-clade neutralizing antibodies, immune restoration, including CD4 + T cell increase particularly in low immunological responders, and reduction of proviral DNA. Phase III efficacy trials in SA are planned both in adult and pediatric populations. Expert commentary: We propose the Tat therapeutic vaccine as a pathogenesis-driven intervention that effectively intensifies cART and may lead to a functional cure and provide new perspectives for prevention and virus eradication strategies.

The Role of Reversed Equatorial Zonal Transport in Terminating an ENSO Event

Science.gov (United States)

Chen, H. C.; Hu, Z. Z.; Huang, B.; Sui, C. H.

2016-02-01

In this study, we demonstrate that a sudden reversal of anomalous equatorial zonal current at the peaking ENSO phase triggers the rapid termination of an ENSO event. Throughout an ENSO cycle, the anomalous equatorial zonal current is strongly controlled by the concavity of the anomalous thermocline meridional structure near the equator. During the ENSO developing phase, the anomalous zonal current in the central and eastern Pacific generally enhances the ENSO growth through its zonal SST advection. In the mature phase of ENSO, however, the equatorial thermocline depth anomalies are reflected in the eastern Pacific and slowly propagate westward off the equator in both hemispheres. As a result, the concavity of the thermocline anomalies near the equator is reversed, i.e., the off-equatorial thermocline depth anomalies become higher than that on the equator for El Niño events and lower for La Niño events. This meridional change of thermocline structure reverses zonal transport rapidly in the central-to-eastern equatorial Pacific, which weakens the ENSO SST anomalies by reversed advection. More importantly, the reversed zonal mass transport weakens the existing zonal tilting of equatorial thermocline and suppresses the thermocline feedback. Both processes are concentrated in the eastern equatorial Pacific and can be effective on subseasonal time scales. These current reversal effects are built-in to the ENSO peak phase and independent of the zonal wind effect on thermocline slope. It functions as an oceanic control on ENSO evolution during both El Niño and La Niña events.

Rapid-rate nonsustained ventricular tachycardia found on implantable cardioverter-defibrillator interrogation: relationship to outcomes in the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial).

Science.gov (United States)

Chen, Jay; Johnson, George; Hellkamp, Anne S; Anderson, Jill; Mark, Daniel B; Lee, Kerry L; Bardy, Gust H; Poole, Jeanne E

2013-05-28

The aim of this study was to examine rapid-rate nonsustained ventricular tachycardia (RR-NSVT) during routine implantable cardioverter-defibrillator (ICD) evaluation in patients with heart failure and its relationship to outcomes. The clinical implications of RR-NSVT identified during routine ICD interrogation are unclear. In this study, the occurrence of RR-NSVT and its association with ICD shocks and mortality in SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial) were examined. The 811 patients who received ICDs in SCD-HeFT constituted the study population. The occurrence of RR-NSVT and its association with ICD shocks and mortality in SCD-HeFT were examined. RR-NSVT was documented on ICD interrogation in 186 of 811 patients (22.9%). The mean duration of RR-NSVT was 26.4 ± 9.1 beats (7.5 ± 2.6 s), with a mean cycle length of 259 ± 32 ms. Polymorphic RR-NSVT accounted for 56% of episodes. Compared with patients without RR-NSVT, those with RR-NSVT were less likely to be taking beta-blockers, statins, or aspirin at enrollment. After adjusting for other known predictors of mortality in SCD-HeFT, RR-NSVT was independently associated with appropriate ICD shocks (hazard ratio: 4.25; 95% confidence interval: 2.94 to 6.14; p interrogation should be considered an important clinical event. RR-NSVT during ICD interrogation is associated with appropriate ICD shocks and all-cause mortality. The clinical evaluation of patients with RR-NSVT should include intensification of medical therapy, particularly beta-blockers, or other appropriate clinical interventions. (Sudden Cardiac Death in Heart Failure Trial [SCD-HeFT]; NCT00000609). Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

TEMPORAL VARIABILITY IN PHYSICAL SPECIATION OF METALS DURING A WINTER RAIN-ON-SNOW EVENT

Science.gov (United States)

Particulate matter in urban rivers transports a significant fraction of pollutants, changes rapidly during storm events and is difficult to characterize. In this study, the physical speciation of trace metals and organic carbon in an urban river and upstream headwaters site in To...

Ionospheric response to a recurrent magnetic storm during an event of High Speed Stream in October 2016.

Science.gov (United States)

Nicoli Candido, C. M.; Resende, L.; Becker-Guedes, F.; Batista, I. S.

2017-12-01

In this work we investigate the response of the low latitude ionosphere to recurrent geomagnetic activity caused by events of High speed streams (HSSs)/Corotating Interaction Regions (CIRs) during the low descending phase of solar activity in the solar cycle 24. Intense magnetic field regions called Corotating Interaction Regions or CIRs are created by the interaction of fast streams and slow streams ejected by long duration coronal holes in Sun. This interaction leads to an increase in the mean interplanetary magnetic field (IMF) which causes moderate and recurrent geomagnetic activity when interacts with the Earth's magnetosphere. The ionosphere can be affected by these phenomena by several ways, such as an increase (or decrease) of the plasma ionization, intensification of plasma instabilities during post-sunset/post-midnight hours and subsequent development of plasma irregularities/spread-F, as well as occurrence of plasma scintillation. Therefore, we investigate the low latitude ionospheric response during moderate geomagnetic storm associated to an event of High Speed Stream occurred during decreasing phase of solar activity in 2016. An additional ionization increasing is observed in Es layer during the main peak of the geomagnetic storm. We investigate two possible different mechanisms that caused these extras ionization: the role of prompt penetration of interplanetary electric field, IEFEy at equatorial region, and the energetic electrons precipitation on the E and F layers variations. Finally, we used data from Digisondes installed at equatorial region, São Luís, and at conjugate points in Brazilian latitudes, Boa Vista and Cachoeira Paulista. We analyzed the ionospheric parameters such as the critical frequency of F layer, foF2, the F layer peak height, hmF2, the F layer bottomside, h'F, the blanketing frequency of sporadic layer, fbEs, the virtual height of Es layer h'Es and the top frequency of the Es layer ftEs during this event.