WorldWideScience

Sample records for rapid economic progress

  1. Rapidly Progressive Quadriplegia and Encephalopathy.

    Science.gov (United States)

    Wynn, DonRaphael; McCorquodale, Donald; Peters, Angela; Juster-Switlyk, Kelsey; Smith, Gordon; Ansari, Safdar

    2016-11-01

    A woman aged 77 years was transferred to our neurocritical care unit for evaluation and treatment of rapidly progressive motor weakness and encephalopathy. Examination revealed an ability to follow simple commands only and abnormal movements, including myoclonus, tongue and orofacial dyskinesias, and opsoclonus. Imaging study findings were initially unremarkable, but when repeated, they demonstrated enhancement of the cauda equina nerve roots, trigeminal nerve, and pachymeninges. Cerebrospinal fluid examination revealed mildly elevated white blood cell count and protein levels. Serial electrodiagnostic testing demonstrated a rapidly progressive diffuse sensory motor axonopathy, and electroencephalogram findings progressed from generalized slowing to bilateral periodic lateralized epileptiform discharges. Critical details of her recent history prompted a diagnostic biopsy. Over time, the patient became completely unresponsive with no further abnormal movements and ultimately died. The differential diagnosis, pathological findings, and diagnosis are discussed with a brief review of a well-known yet rare diagnosis.

  2. Climate economics in progress 2011; Climate economics in progress 2011

    Energy Technology Data Exchange (ETDEWEB)

    De Perthuis, Christian [Paris-Dauphine University (France); Jouvet, Pierre-Andre [Paris-Ouest University (France); Trotignon, Raphael; Simonet, Gabriela; Boutueil, Virginie [Climate Economics Chair, Paris-Dauphine University (France)

    2011-10-01

    Climate Economics in Progress offers a global overview of the present status of action on climate change. Drawing on the most recent data, it analyzes the development of carbon markets in Europe and other parts of the world. It also examines the conditions for including major players such as China and new sectors such as agriculture, forestry and transport in the fight against global warming. The book is essential reading for anyone wishing to understand current advances in climate control, which could pave the way for a new form of economic growth. The book brings together a group of researchers whose goal is to make the link between academic research on the economics of climate change and the implementation of operational tools, thereby allowing the climate issue to be integrated into the functioning of the real economy

  3. Economic Growth of a Rapidly Developing Economy: Theoretical Formulation

    Directory of Open Access Journals (Sweden)

    Oleg Sergeyevich Sukharev

    2016-06-01

    Full Text Available The subject matter of the article is the description of economic growth. Modern economy is characterized by a high rate of changes. These changes are the limiting parameters of modern development, which requires a modification of the basic models of growth, the substantiation of the expediency and necessity of a rapid development strategy. In a simple mathematical form, the statement of the problem of economic growth in the “green economy” is examined, in which the costs of environmental measures are not considered a priori as hampering economic development (as it is common for a number of modern neoclassical and neo-Keynesian growth models. The methodological basis of the article are the econometric approach and modelling method. The article has a theoretical character. The main hypothesis supposes that the rapid development strategy cannot make an adequate development strategy under certain conditions, but may be acceptable in other its specific conditions. In this sense, the important growth conditions are the availability of resources, the effectiveness of institutions and the current economic structure, the technological effectiveness of economy, as well as the conditions of technological development (“green economy” and the path of such development. In the article, on the theoretical level of analysis, the substantiation of the adequacy of the rapid development strategy for an economic system is given, whose goal is to achieve the standard of living of the countryleader. Based on the assumptions introduced, the period for which the rapid development strategy might be implemented and the economic lag of the country might be reduced from the country-leader is determined. The conditions that ensure the impact of innovations on the rate of economic development are summarized. The introduced range of dependencies and relations can be useful for the elaboration of the theory of innovation development and for the formation of a new

  4. Economic analyses of rapid population growth.

    Science.gov (United States)

    Birdsall, N

    1989-01-01

    "Discussion of the macroeconomic consequences of rapid population growth is organized into three schools: pessimists, optimists, and the recent revisionists. For the revisionists, differing views are presented about the pervasiveness and relevance of market failures, such as the negative externalities of childbearing, and about the ability of families and institutions to adjust rapidly to changes brought on by rapid population growth. A welfare economics approach is used to review the merits of various public policies to reduce fertility, including public financing of family planning services and taxes and incentives associated with childbearing." The focus is on developing countries. excerpt

  5. SOCIAL PROGRESS AND ECONOMIC PROJECTS FOR DISADVANTAGED GROUPS IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Aurelian Virgil BALUTA

    2016-12-01

    Full Text Available The paper aims to analyse the social progress, social politics, social law and successful projects applicable to the some disadvantaged groups: Roma people and woman. Inclusion of Roma people is analysed from economic point of view. The economic problems of equality by gender is presented in terms of labour rate and other relevant ratio. For Roma people the focus of analyse is also on labour involvement. The chapters of the communication are: introduction, literature review ( state of art in the field of social progress, theoretical background, tools for social progress in EU, economic inclusion of Roma population, economic equality by gender, conclusions.

  6. Female Progress and Discrimination. An Economic Perspective

    OpenAIRE

    Sandra E. Black

    2005-01-01

    In the last 20 years, women’s economic progress has been staggering; this progress is particularly startling given that this has also been a period of marked increases in income inequality overall, declining relative wages of blacks, and declining real wages of low-skilled workers. Recent work has proposed a number of possible explanations for the progress of women, including changing social norms (in part facilitated by technological/pharmaceutical advances), increasing skill acquisition, ch...

  7. The relative economic progress of male foreign workers in Kuwait.

    Science.gov (United States)

    Al-qudsi, S S; Shah, N M

    1991-01-01

    "A human capital framework is utilized to examine the economic progress of nine nationality groups of foreign workers [in Kuwait] using data from the 1983 national Labor Survey. The sources of earnings' variations of particular interest to us included different degrees of education and experience transferability, occupational affiliation and ethnic background. In general, the results derived from the analysis suggest that 1) foreign workers achieve a discernible economic progress as their residence lengthens; 2) the rate of economic progress varies depending on worker's education, home and Kuwait-specific experience, occupational status and ethnic background; and 3) about one third of the earnings inequality is due to unexplained factors including discrimination." excerpt

  8. Climate economics in progress 2011

    International Nuclear Information System (INIS)

    De Perthuis, Christian; Jouvet, Pierre-Andre; Trotignon, Raphael; Simonet, Gabriela; Boutueil, Virginie

    2011-01-01

    Climate Economics in Progress offers a global overview of the present status of action on climate change. Drawing on the most recent data, it analyzes the development of carbon markets in Europe and other parts of the world. It also examines the conditions for including major players such as China and new sectors such as agriculture, forestry and transport in the fight against global warming. The book is essential reading for anyone wishing to understand current advances in climate control, which could pave the way for a new form of economic growth. The book brings together a group of researchers whose goal is to make the link between academic research on the economics of climate change and the implementation of operational tools, thereby allowing the climate issue to be integrated into the functioning of the real economy

  9. Serum metabolomics of slow vs. rapid motor progression Parkinson's disease: a pilot study.

    Science.gov (United States)

    Roede, James R; Uppal, Karan; Park, Youngja; Lee, Kichun; Tran, Vilinh; Walker, Douglas; Strobel, Frederick H; Rhodes, Shannon L; Ritz, Beate; Jones, Dean P

    2013-01-01

    Progression of Parkinson's disease (PD) is highly variable, indicating that differences between slow and rapid progression forms could provide valuable information for improved early detection and management. Unfortunately, this represents a complex problem due to the heterogeneous nature of humans in regards to demographic characteristics, genetics, diet, environmental exposures and health behaviors. In this pilot study, we employed high resolution mass spectrometry-based metabolic profiling to investigate the metabolic signatures of slow versus rapidly progressing PD present in human serum. Archival serum samples from PD patients obtained within 3 years of disease onset were analyzed via dual chromatography-high resolution mass spectrometry, with data extraction by xMSanalyzer and used to predict rapid or slow motor progression of these patients during follow-up. Statistical analyses, such as false discovery rate analysis and partial least squares discriminant analysis, yielded a list of statistically significant metabolic features and further investigation revealed potential biomarkers. In particular, N8-acetyl spermidine was found to be significantly elevated in the rapid progressors compared to both control subjects and slow progressors. Our exploratory data indicate that a fast motor progression disease phenotype can be distinguished early in disease using high resolution mass spectrometry-based metabolic profiling and that altered polyamine metabolism may be a predictive marker of rapidly progressing PD.

  10. Serum metabolomics of slow vs. rapid motor progression Parkinson's disease: a pilot study.

    Directory of Open Access Journals (Sweden)

    James R Roede

    Full Text Available Progression of Parkinson's disease (PD is highly variable, indicating that differences between slow and rapid progression forms could provide valuable information for improved early detection and management. Unfortunately, this represents a complex problem due to the heterogeneous nature of humans in regards to demographic characteristics, genetics, diet, environmental exposures and health behaviors. In this pilot study, we employed high resolution mass spectrometry-based metabolic profiling to investigate the metabolic signatures of slow versus rapidly progressing PD present in human serum. Archival serum samples from PD patients obtained within 3 years of disease onset were analyzed via dual chromatography-high resolution mass spectrometry, with data extraction by xMSanalyzer and used to predict rapid or slow motor progression of these patients during follow-up. Statistical analyses, such as false discovery rate analysis and partial least squares discriminant analysis, yielded a list of statistically significant metabolic features and further investigation revealed potential biomarkers. In particular, N8-acetyl spermidine was found to be significantly elevated in the rapid progressors compared to both control subjects and slow progressors. Our exploratory data indicate that a fast motor progression disease phenotype can be distinguished early in disease using high resolution mass spectrometry-based metabolic profiling and that altered polyamine metabolism may be a predictive marker of rapidly progressing PD.

  11. Case of Rapid Progression of Hemiatrophy on the Face: A New Clinical Entity?

    Directory of Open Access Journals (Sweden)

    Hisashi Nomura

    2015-01-01

    Full Text Available A lot of diseases, including lupus profundus, morphea, lipodystrophy, and Parry-Romberg syndrome, may manifest progressive hemifacial atrophy. These diseases usually progress slowly and rapid progression of atrophy is extremely rare. We report a case of elderly-onset rapid progression of hemifacial atrophy only in three weeks. Our case did not meet variable differential diagnoses. We discuss the clinical character of the patient against the past of literature and suppose it may be a new clinical entity.

  12. Syndromes of rapidly progressive cognitive decline-our experience

    Directory of Open Access Journals (Sweden)

    Sadanandavalli Retnaswami Chandra

    2017-01-01

    Full Text Available Background: Dementias are fairly slowly progressive degenerative diseases of brain for which treatment options are very less and carry a lot of burden on family and society. A small percentage of them are rapidly progressive and mostly carry a different course outcome. However, there are no definite criteria other than the time line for these patients. Aims: The aim of this was to identify and categorize the causes and course of rapidly progressive dementias seen in our center. Settings and Design: Patients who presented with rapid deterioration of cognitive functions within weeks to 1 year between 2011 and December 2016 were evaluated. Patients and Methods: All patients underwent all mandatory tests for dementia including brain imaging. Complete vasculitis workup, autoimmune encephalitis profile including Voltage Gated Potassium Channel, N-methyl-D-aspartic acid receptor, glutamic acid-decarboxylase, thyroid-peroxidase antibody, cerebrospinal fluid, and other special tests such as duodenal biopsy and paraneoplastic workup were done based on clinical indications. Results and Conclusions: Out of 144 patients 42 had immune-mediated encephalopathy, 18 had Creutzfeldt-Jakob disease, 3 had Vitamin B12 deficiency, 63 had infection with neurocysticercosis, 7 had tuberculosis, 2 had HIV, 1 had herpes simplex encephalitis, 1 had neurosyphilis, 1 Whipples disease, 1 had Subacute Sclerosing Panencephalitis, 1 had Mass lesion, 3 had Frontotemporal dementia, and 3 had small vessel disease. Good majority of these patients have infective and immune-mediated causes and less number belong to degenerative group. Therefore, caution is needed to look for treatable cause as it carries a different treatment options and outcome.

  13. Frosted branch angiitis associated with rapidly progressive glomerulonephritis.

    Directory of Open Access Journals (Sweden)

    Gupta Amod

    2002-01-01

    Full Text Available Simultaneous occurrence of frosted branch angiitis and immune-mediated rapidly progressive glomerulonephritis is reported. The two diseases possibly share a common immune mechanism. Patients of frosted branch angiitis should undergo complete systemic evaluation including renal function tests even if the patient is systemically asymptomatic.

  14. Pakistan strong industrial base urged for economic progress

    CERN Multimedia

    2001-01-01

    A conference organized by Pakistan Nuclear Society urged that Pakistan should develop a strong industrial base and capability to export equipment for economic progress. The chairmen of PAEC pointed out that Pakistan is already showing remarkable progress in export of science-related equipment to CERN. He also asked scientists to wage a war against Pakistans inability to acquire indigenous technology (1 page).

  15. Rapid estimation of the economic consequences of global earthquakes

    Science.gov (United States)

    Jaiswal, Kishor; Wald, David J.

    2011-01-01

    The U.S. Geological Survey's (USGS) Prompt Assessment of Global Earthquakes for Response (PAGER) system, operational since mid 2007, rapidly estimates the most affected locations and the population exposure at different levels of shaking intensities. The PAGER system has significantly improved the way aid agencies determine the scale of response needed in the aftermath of an earthquake. For example, the PAGER exposure estimates provided reasonably accurate assessments of the scale and spatial extent of the damage and losses following the 2008 Wenchuan earthquake (Mw 7.9) in China, the 2009 L'Aquila earthquake (Mw 6.3) in Italy, the 2010 Haiti earthquake (Mw 7.0), and the 2010 Chile earthquake (Mw 8.8). Nevertheless, some engineering and seismological expertise is often required to digest PAGER's exposure estimate and turn it into estimated fatalities and economic losses. This has been the focus of PAGER's most recent development. With the new loss-estimation component of the PAGER system it is now possible to produce rapid estimation of expected fatalities for global earthquakes (Jaiswal and others, 2009). While an estimate of earthquake fatalities is a fundamental indicator of potential human consequences in developing countries (for example, Iran, Pakistan, Haiti, Peru, and many others), economic consequences often drive the responses in much of the developed world (for example, New Zealand, the United States, and Chile), where the improved structural behavior of seismically resistant buildings significantly reduces earthquake casualties. Rapid availability of estimates of both fatalities and economic losses can be a valuable resource. The total time needed to determine the actual scope of an earthquake disaster and to respond effectively varies from country to country. It can take days or sometimes weeks before the damage and consequences of a disaster can be understood both socially and economically. The objective of the U.S. Geological Survey's PAGER system is

  16. Budgeting For National Economic Consolidation And Progression ...

    African Journals Online (AJOL)

    The paper exemplifies genuine concern and empathy for the perceived unimpressive pace of growth and development of Nigeria\\'s national economy. The 2007 budget aptly directed at consolidation is crystallized as affording stakeholders the potent drive towards meaningful progression in national economic management ...

  17. Impact of Scientific and Technological Progress on Economic Development - the Views of Some Nobel Laureates of the Economic Science

    OpenAIRE

    Florentina Xhelili KRASNIQI; Nexhmie Berisha VOKSHI

    2017-01-01

    There are different authors' opinions and numerous theories according to which scientific technological progress is a determining factor of the economic development. The paper aims to present the contributions of some Nobel laureates to the impact of scientific and technological progress on economic development such as Arrow, Debreu, Hicks, Solow, Kuznets, Kantorovich and Stiglitz. The research results of their contributions show that scientific technological progress is considered as a sour...

  18. Impact of Scientific and Technological Progress on Economic Development - the Views of Some Nobel Laureates of the Economic Science

    Directory of Open Access Journals (Sweden)

    Florentina Xhelili KRASNIQI

    2017-12-01

    Full Text Available There are different authors' opinions and numerous theories according to which scientific technological progress is a determining factor of the economic development. The paper aims to present the contributions of some Nobel laureates to the impact of scientific and technological progress on economic development such as Arrow, Debreu, Hicks, Solow, Kuznets, Kantorovich and Stiglitz. The research results of their contributions show that scientific technological progress is considered as a source of economic development but this advanced technology to be widely and effectively used should be accompanied by such ideological and institutional adjustments that guarantee the reasonable use of innovations produced by the huge improvements of human knowledge.

  19. Prospects for reconciling the conflict between economic growth and biodiversity conservation with technological progress.

    Science.gov (United States)

    Czech, Brian

    2008-12-01

    The conflict between economic growth and biodiversity conservation is understood in portions of academia and sometimes acknowledged in political circles. Nevertheless, there is not a unified response. In political and policy circles, the environmental Kuznets curve (EKC) is posited to solve the conflict between economic growth and environmental protection. In academia, however, the EKC has been deemed fallacious in macroeconomic scenarios and largely irrelevant to biodiversity. A more compelling response to the conflict is that it may be resolved with technological progress. Herein I review the conflict between economic growth and biodiversity conservation in the absence of technological progress, explore the prospects for technological progress to reconcile that conflict, and provide linguistic suggestions for describing the relationships among economic growth, technological progress, and biodiversity conservation. The conflict between economic growth and biodiversity conservation is based on the first two laws of thermodynamics and principles of ecology such as trophic levels and competitive exclusion. In this biophysical context, the human economy grows at the competitive exclusion of nonhuman species in the aggregate. Reconciling the conflict via technological progress has not occurred and is infeasible because of the tight linkage between technological progress and economic growth at current levels of technology. Surplus production in existing economic sectors is required for conducting the research and development necessary for bringing new technologies to market. Technological regimes also reflect macroeconomic goals, and if the goal is economic growth, reconciliatory technologies are less likely to be developed. As the economy grows, the loss of biodiversity may be partly mitigated with end-use innovation that increases technical efficiency, but this type of technological progress requires policies that are unlikely if the conflict between economic growth

  20. The Model of Optimum Economic Growth with the Induced Scientific-Technological Progress

    Directory of Open Access Journals (Sweden)

    Dilenko Viktor A.

    2017-07-01

    Full Text Available On the basis of the economic dynamics of the Harrod – Domar model, a model of optimum economic growth in line with the induced scientific-technological progress (STP has been built. In order to reflect the induced scientific-technological progress, with this model is proposed to further allocate the income element that is specially used for the investment of innovation activity, implementation of which reduces the capital intensity in development of the discussed economy. For the simplest way of presenting an economic mechanism for the investment of induced STP, analytical solutions of an appropriate task in optimum management have been obtained. Studying these decisions allowed to reveal the characteristics of the impact of parameters of scientific-technological progress and the analyzed economic system on choosing the best trajectory for its evolution. Possible directions for further developing the results presented can be considered the tasks in building and analyzing models of optimum economic growth that implement different investment options for the induced STP, as well as the models in which this investment mechanism is not exogenouslyed, but rather the result of the corresponding economic-mathematical research.

  1. Workforce Training and Economic Development Fund: 2015 Annual Progress Report

    Science.gov (United States)

    Iowa Department of Education, 2015

    2015-01-01

    The Department of Education, Division of Community Colleges, will annually provide the State Board of Education with The Workforce Training and Economic Development (WTED) Fund Annual Progress Report. Administration and oversight responsibility for the fund was transferred from the Iowa Economic Development Authority to the Iowa Department of…

  2. Rapidly Progressive Spontaneous Spinal Epidural Abscess

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    Abdurrahman Aycan

    2016-01-01

    Full Text Available Spinal epidural abscess (SEA is a rare disease which is often rapidly progressive. Delayed diagnosis of SEA may lead to serious complications and the clinical findings of SEA are generally nonspecific. Paraspinal abscess should be considered in the presence of local low back tenderness, redness, and pain with fever, particularly in children. In case of delayed diagnosis and treatment, SEA may spread to the epidural space and may cause neurological deficits. Magnetic resonance imaging (MRI remains the method of choice in the diagnosis of SEA. Treatment of SEA often consists of both medical and surgical therapy including drainage with percutaneous entry, corpectomy, and instrumentation.

  3. Indicators of Economic Progress: The Power of Measurement and Human Welfare

    Directory of Open Access Journals (Sweden)

    Garry Jacobs

    2010-10-01

    Full Text Available Right measurement is a powerful instrument for social progress; wrong or imprecise measurement a source of hazard and even havoc. The essential purpose of economic activity is the promotion of human development, welfare and well-being in a sustainable manner, and not growth for growth’s sake, yet we lack effective measures to monitor progress toward these objectives. Advances in understanding, theory and measurement must necessarily proceed hand in hand. A companion article in this publication sets forth the urgent need for new theory in economics. This article sets forth the complementary need for new measures. The stakes are high and the choice is ours. On one side, rising social tensions, recurring financial crises and ecological disaster; on the other, the progressive unfolding and development of human capacity in harmony with Nature. The deficiencies of GDP as a measure are well-documented by leading economists Kuznets, Tobin, Tinbergen and many others; but, unfortunately, decision-making still remains largely based on GDP, valid during 1930-70 perhaps, but certainly inappropriate today. The challenge is to derive more appropriate indicators to reflect real, sustainable economic welfare, social development and human wellbeing. The attributes that have made GDP so successful are often overlooked — it provides clear objectives for policy and decision-making. We propose new composite indicator, HEWI, which can be used to guide decision-making, which retains the strengths associated with GDP, while substantially enhancing its value as a measure of human economic development. HEWI monitors progress on factors that contribute prominently to present economic welfare — household consumption, government welfare-related expenditure, income inequality and unemployment — as well as factors that have the potential to significantly enhance long term sustainability — education, fossil fuel energy efficiency and net household savings. The index

  4. From scientific progress to economic growth the economics and the economy of science

    CERN Document Server

    Witte, Frank

    2017-01-01

    he past few centuries have seen an enormous increase in living standards in many parts of the world and these economies have become more complex than ever before. At the same time, progress in science and technology has reached unprecedented heights, taking us far beyond the wildest dreams of a few generations ago. Questions as to how science, technology and the economy interact are pertinent and important ones, whose partial answers require a view "from across the fence" between disciplines. This book provides an introduction to the vast and varied field of the economics of science. It is a unique blend of an economic perspective on the way science works, what makes scientists tick, and a study of the impact of scientific and technological progress on economies and their growth. Whether it is about the speculative market of ideas or science and technology as engines of the economy, there is something here for economists, engineers and scientists alike.

  5. [Autopsy case of Lissauer's general paresis with rapidly progressive left hemiparesis].

    Science.gov (United States)

    Kato, Hiroko; Yoshida, Mari; Ando, Tetsuo; Sugiura, Makoto; Hashizume, Yoshio

    2009-06-01

    A 48-years-old man presented with slowly progressive bradykinesia, personality change and rapidly progressive left hemiparesis. On admission, he presented dementia, poor judgment, left hemiparesis. MRI revealed a widespread high intensity area in right hemisphere and MRA was almost normal. Serological tests of serum and CSF demonstrated high titers of antibodies to Treponema pallidum. He was treated for syphilis with daily penicillin injections without improvement. He died of sepsis eight months after admission. At autopsy, the brain weighed 1,100 g and the right cerebral hemisphere was atrophic, especially in frontal base, temporal, parietal, angular, and posterior regions covered by thickened, fibrotic leptomeninges. Microscopically, chronic meningoencephalitis was observed. Severe neuronal loss with gliosis was seen in the right cerebral cortices. Scattered rod-shaped microglia and inflammatory cell infiltration were visible in the cerebral parenchyma. The dorsal column of the spinal cord was not involved and meningovascular syphilis was unclear. The distribution of the encephalitic lesions was well correlated with the clinical and neuroradiological findings. This was a rare autopsy case presenting Lissauer's general paresis, clinically manifesting as rapidly progressive stroke-like episode.

  6. An Unusual Case of Rapidly Progressive Hyperbilirubinemia

    Directory of Open Access Journals (Sweden)

    Kimberly M. Thornton

    2013-01-01

    Full Text Available We present an unusual case of hyperbilirubinemia with rapid early progression leading to bilirubin encephalopathy in a term neonate. Despite early recognition and intervention, the total serum bilirubin reached a maximum level of 39 mg/dL at 32 hours of life. Prior to an emergent exchange transfusion, the patient’s diagnostic evaluation was significant for Coombs-negative microangiopathic hemolytic anemia and thrombocytopenia. Further testing revealed a deficiency of ADAMTS13 protein, or von Willebrand factor-cleaving protease, a finding diagnostic of congenital thrombotic thrombocytopenic purpura, or Upshaw-Schulman syndrome. This rare disease is often misdiagnosed, especially in the newborn period.

  7. Clinicopathological Correlates in a PRNP P102L Mutation Carrier with Rapidly Progressing Parkinsonism-dystonia

    Science.gov (United States)

    Umeh, Chizoba C.; Kalakoti, Piyush; Greenberg, Michael K; Notari, Silvio; Cohen, Yvonne; Gambetti, Pierluigi; Oblak, Adrian L.; Ghetti, Bernardino; Mari, Zoltan

    2015-01-01

    Parkinsonism-dystonia is rare in carriers of PRNP P102L mutation. Severity and distribution of prion protein (PrP) deposition may influence the clinical presentation. We present such clinic-pathological correlation in a 56-year-old male with a PRNP P102L mutation associated with a phenotype characterized by rapidly progressing parkinsonism-dystonia. The patient was studied clinically (videotaped exams, brain MRIs); molecular genetically (gene sequence analysis); and neuropathologically (histology, immunohistochemistry) during his 7-month disease course. The patient had parkinsonism, apraxia, aphasia, and dystonia, which progressed rapidly. Molecular genetic analysis revealed PRNP P102L mutation carrier status. Brain MRIs revealed progressive global volume loss and T2/FLAIR hyperintensity in neocortex and basal ganglia. Postmortem examination showed neuronal loss, gliosis, spongiform changes, and PrP deposition in the striatum. PrP immunohistochemistry revealed widespread severe PrP deposition in the thalamus and cerebellar cortex. Based on the neuropathological and molecular-genetic analysis, the rapidly progressing parkinsonism-dystonia correlated with nigrostriatal, thalamic, and cerebellar pathology. PMID:27617269

  8. Rapid progression of gliomatosis cerebri to secondary glioblastoma, factors that affects the progression rate: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hee Kyung; Yu, In Kyu; Kim, Seung Min; Kim, Joo Heon; Lee, Seung Hoon; Lee, Seung Yeon [Eulji University Hospital, Daejeon (Korea, Republic of)

    2017-03-15

    Glioblastomas may develop de novo or through progression from low-grade or anaplastic astrocytomas. The term 'primary glioblastoma' refers to a glioblastoma that lacks a precursor lesion and has a clinical history of less than three months. On the other hand, the term 'secondary glioblastoma' indicates that the glioblastoma has progressed from a low-grade tumor after a long latency period and often manifests in younger patients. These subtypes of glioblastoma develop via different genetic pathways, and they differ in prognosis and response to therapy. Thus, differential diagnosis of these subtypes and prediction of the factors that affect the progression from low-grade diffuse astrocytoma to secondary glioblastoma would be clinically very important. We present a rare case of secondary glioblastoma, which developed only three months after the follow up imaging evaluations, with a history of low grade glioma, and present the factors that cause rapid progression.

  9. Economics of Privacy: Users'€™ Attitudes and Economic Impact of Information Privacy Protection

    OpenAIRE

    Frik, Alisa

    2017-01-01

    This doctoral thesis consists of three essays within the field of economics of information privacy examined through the lens of behavioral and experimental economics. Rapid development and expansion of Internet, mobile and network technologies in the last decades has provided multitudinous opportunities and benefits to both business and society proposing the customized services and personalized offers at a relatively low price and high speed. However, such innovations and progress have al...

  10. ANCA-GBM dot-blot : Evaluation of an assay in the differential diagnosis of patients presenting with rapidly progressive glomerulonephritis

    NARCIS (Netherlands)

    Rutgers, Abraham; Damoiseaux, Jan; Roozendaal, Caroline; Limburg, Pieter C; Stegeman, Coen A; Tervaert, Jan Willem Cohen

    Rapidly progressive glomerulonephritis (RPGN) is characterized by rapid and progressive loss of renal function and the presence of crescentic glomerulonephritis (CGN). Early diagnosis and appropriate treatment is mandatory to prevent death and/or renal failure. We have evaluated an ANCA-GBM dot-blot

  11. [Rapidly progressive puberty in a patient with mosaic Turner syndrome: a case report and literature review].

    Science.gov (United States)

    Liang, Y; Wei, H; Yu, X; Huang, W; Luo, X P

    2017-02-02

    Objective: To explore the clinical characteristics of diagnosis and treatment in patients with Turner syndrome and rapidly progressive puberty. Method: A rare case of rapidly progressive puberty in Turner syndrome with a mosaic karyotype of 45, X/46, X, del(X)(p21)(80%/20%)was diagnosed at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology in January. 2015. Clinical characteristics and the related literature were reviewed. Original papers on precocious puberty or rapidly progressive puberty in Turner syndrome, published until Apr. 2016 were retrieved at PubMed and CNKI databases by the use of the key words "Turner syndrome" , "precocious puberty" and "rapidly progressive puberty" . Result: The patient was born at term with birth weight of 2 450 g and was diagnosed with SGA at 3 years of age for the first evaluating of growth and development. Then recombined human growth hormone (rhGH )was given at 4 years of age due to short stature (heightTurner syndrome is reported. Although short stature and ovarian dysgenesis are common in TS, precocious puberty may occur in TS, which is liable to cause delayed diagnosis and misdiagnosis. Careful examination is recommended for patients with unusual growth pattern, even though girls have normal height in accord with standard growth curve or spontaneous puberty. Evaluation for TS and subsequent investigation should be prompted.

  12. Adult-onset phenylketonuria with rapidly progressive dementia and parkinsonism.

    Science.gov (United States)

    Tufekcioglu, Zeynep; Cakar, Arman; Bilgic, Basar; Hanagasi, Hasmet; Gurvit, Hakan; Emre, Murat

    2016-06-01

    Phenylketonuria (PKU) is an autosomal recessive metabolic disorder due to mutations in the phenylalanine hydroxylase (PAH) gene, which converts phenylalanine (PHE) to tyrosine. Although it is principally a childhood disorder, in rare cases, the first signs of PKU may develop in late adulthood resembling common neurological diseases. Here we report a 59-year-old, previously normal functioning man who was admitted with blurred vision, cognitive problems, and gait difficulty that began 8 months before. He had brisk reflexes and left side dominant parkinsonism. His Mini-Mental State Examination (MMSE) score was 25/30, and neuropsychological evaluation revealed a dysexecutive syndrome with simultanagnosia and constructional apraxia. His Clinical Dementia Rating score (CDR) was 1. Cranial MRI revealed bilateral diffuse hyperintense lesions in parietal and occipital white matter in T2, fluid-attenuated inversion recovery, and diffusion weighted images. Diagnostic workup for rapidly progressive dementias was all normal except PHE level which was found to be highly elevated (1075 μmol/L, normal 39-240 μmol/L) with normal tyrosine level (61.20 μmol/L, normal 35-100 μmol/L). Three months after PHE-restricted diet, his cognitive impairment and signs of parkinsonism significantly improved, with MRI scan unchanged. This case demonstrates that late-onset PKU is a rare, treatable cause of rapidly progressive dementia and parkinsonism with certain constellations such as consanguinity and white matter abnormalities (WMAs) in imaging.

  13. [Outcome of rapidly progressive glomerulonephritis post-streptococcal disease in children].

    Science.gov (United States)

    Jellouli, Manel; Maghraoui, Sondos; Abidi, Kamel; Hammi, Yosra; Goucha, Rim; Naija, Ouns; Zarrouk, Chokri; Gargah, Tahar

    2015-11-01

    Rapidly progressive glomerulonephritis is a rare form of postinfectious glomerulonephritis. The aim of this study was to describe the outcome of our patients with severe post-streptococcal glomerulonephritis. This retrospective study was conducted in the department of pediatrics in Charles-Nicolle Hospital during a period of 13 years (1997-2009). Twenty-seven children were identified. The mean age was 8.7 years. All patients presented renal failure at presentation. The mean serum creatinine at presentation was 376.9 μmol/L. Six patients presented nephrotic syndrome. Twenty-six children had renal biopsies. Renal biopsies showed crescents in 24 cases. Eighteen children received pulse dose of corticosteroids (66.6%) and 6 children (22%) received pulse dose of corticosteroids and cyclophosphamide. Eleven patients required dialysis. At last follow-up, 22 patients (81.5%) had normal kidney function, 2 had renal dysfunction and 3 reached end stage renal disease. The only significant determinant for renal survival was the supportive dialysis (P=0.015). Rapidly progressive glomerulonephritis is uncommon. There have been significant advancements in supportive, as well as specific therapy, but the outcome continues to be poor. Copyright © 2015 Association Société de néphrologie. Published by Elsevier SAS. All rights reserved.

  14. eRME - Rapid Maxillary Expansion in the economic way

    Directory of Open Access Journals (Sweden)

    Sonali Mahadevia

    2011-01-01

    Full Text Available Aim and Objectives: Rapid Maxillary Expansion constitutes a routine clinical procedure in orthodontics, involving separation of mid-palatine suture which is usually done with help of the Hyrax screw. However, because of its high cost, the use has been limited, especially in institutions. So, the purpose of this study was to construct an economical device which can expand the maxillary arch in growing patients. Materials and Methods: Six patients having constricted maxilla and posterior skeletal crossbite were randomly selected from the Department of Orthodontics. A unique, easy and simple alternative device for expanding the maxillary arch called economic Rapid Maxillary Expander (eRME has been fabricated at about one-tenth the cost of the conventional Hyrax. Pre- and post-treatment effects were statistically tested by using paired t-test at 0.05 level of significance. Results and Conclusion: The study results showed an average expansion in canine, premolar and molar regions of 4.4 mm, 6.8 mm and 9.4 mm, respectively, having significant difference pre-and post-treatment. Thus, it shows that maxillary expansion is efficiently possible with the application of this newly constructed device named eRME. This appliance also acts as a fixed retainer to avoid relapse, hence negating the need for a separate retainer.

  15. Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons

    DEFF Research Database (Denmark)

    Kamara, David A; Nielsen, Lene Ryom; Ross, Michael

    2014-01-01

    No consensus exists on how to define abnormally rapid deterioration in renal function (Rapid Progression, RP). We developed an operational definition of RP in HIV-positive persons with baseline estimated glomerular filtration rate (eGFR) >90ml/min/1.73m2 (using Cockcroft Gault) in the Data...

  16. Rapidly progressive glomerulonephritis in adolescents – aetiology and treatment based on case reports

    Directory of Open Access Journals (Sweden)

    Beata Banaszak

    2017-06-01

    Full Text Available Rapidly progressive glomerulonephritis is a disease characterised by an abrupt drop in glomerular filtration rate in a short period of time, which is caused by crescent formation seen in at least 50% of glomeruli. Two cases presented below illustrate rapid progressive glomerulonephritis in adolescents as a disease of heterogeneous aetiology that can develop both in the course of primary glomerulopathies and glomerulopathies secondary to systemic vasculitis. In the first case of an 11-year-old girl, nephritic syndrome with renal failure was accompanied by the presence of anti-myeloperoxidase antibodies in the serum, which in combination with the histopathological picture of the kidneys indicating pauci-immune rapidly progressive glomerulonephritis was the basis for the diagnosis of renal limited vasculitis. In the second case of a 16-year-old boy, an adverse course of acute post-streptococcal glomerulonephritis with features of severe and persistent glomerular filtration impairment was an indication for the verification of the diagnosis and identification of rapidly progressive glomerulonephritis based on a biopsy examination. Prompt diagnosis and inclusion of combined immunosuppressive therapy provided the chance to preserve renal function.

  17. Comprehensive and Methodical: Diagnostic and Management Approaches to Rapidly Progressive Dementia.

    Science.gov (United States)

    Mahajan, Supriya; Appleby, Brian S

    2017-09-30

    Purpose of review The sudden emergence of a change in cognitive abilities or behavior is an important symptom that warrants medical evaluation and may represent the early stages of a rapidly progressive dementia (RPD). To correctly ascertain the cause of RPD in a given patient, the clinician must be methodical and knowledgeable about the range of potential causes and must move forward with supportive treatment, and in some cases empiric treatment, based on clinical features alone. Recent findings Significant advances in prion disease biomarkers, the molecular features of rapidly progressive Alzheimer's disease, and new detection of autoimmune limbic encephalitis disease entities have caused a shift in the diagnostic and treatment framework of RPD. Additionally, in the past decade, emerging retrospective data have led to suggested treatments in autoimmune encephalitis that, if instituted early, can protect patients against residual deficits and disease relapse. Summary Here, we provide an integrative clinical and diagnostic treatment approach that is applicable to the various forms of RPD. We have highlighted the clinical features of selected types of RPD that have experienced advances in the last 10-15 years.

  18. Poverty Reduction and Shared Prosperity in Moldova : Progress and Prospects

    OpenAIRE

    World Bank Group

    2016-01-01

    Moldova has experienced rapid economic growth in the past decade, which has been accompanied by reductions in poverty and good performance in shared prosperity. Nonetheless, Moldova remains one of the poorest countries in Europe and faces challenges in sustaining the progress. The challenges for progress include spatial and cross-group inequalities, particularly because of unequal access t...

  19. Early depletion of proliferating B cells of germinal center in rapidly progressive simian immunodeficiency virus infection

    International Nuclear Information System (INIS)

    Zhang Zhiqiang; Casimiro, Danilo R.; Schleif, William A.; Chen, Minchun; Citron, Michael; Davies, Mary-Ellen; Burns, Janine; Liang, Xiaoping; Fu, Tong-Ming; Handt, Larry; Emini, Emilio A.; Shiver, John W.

    2007-01-01

    Lack of virus specific antibody response is commonly observed in both HIV-1-infected humans and SIV-infected monkeys with rapid disease progression. However, the mechanisms underlying this important observation still remain unclear. In a titration study of a SIVmac239 viral stock, three out of six animals with viral inoculation rapidly progressed to AIDS within 5 months. Unexpectedly, there was no obvious depletion of CD4 + T cells in both peripheral and lymph node (LN) compartments in these animals. Instead, progressive depletion of proliferating B cells and disruption of the follicular dendritic cell (FDC) network in germinal centers (GC) was evident in the samples collected at as early as 20 days after viral challenge. This coincided with undetectable, or weak and transient, virus-specific antibody responses over the course of infection. In situ hybridization of SIV RNA in the LN samples revealed a high frequency of SIV productively infected cells and large amounts of accumulated viral RNA in the GCs in these animals. Early severe depletion of GC proliferating B cells and disruption of the FDC network may thus result in an inability to mount a virus-specific antibody response in rapid progressors, which has been shown to contribute to accelerated disease progression of SIV infection

  20. Rapidly Progressive Corticobasal Degeneration Syndrome

    Directory of Open Access Journals (Sweden)

    Ana Herrero Valverde

    2011-08-01

    Full Text Available Introduction: Corticobasal syndrome (CBS has a heterogeneous clinical presentation with no specific pathologic substratum. Its accurate diagnosis is a challenge for neurologists; in order to establish CBS definitively, postmortem confirmation is required. Some clinical and radiological features can help to distinguish it from other neurodegenerative conditions, such as Creutzfeldt-Jakob disease (CJD. Clinical Case: A 74-year-old woman presented with language impairment, difficulty in walking and poor attentiveness that had begun 10 days before. Other symptoms, such as asymmetrical extra-pyramidal dysfunction, limb dystonia and ‘alien limb’ phenomena, were established over the next 2 months, with rapid progression. Death occurred 3 months after symptom onset. Laboratory results were normal. Initially, imaging only showed restricted diffusion with bilateral parieto-occipital gyri involvement on DWI-MRI, with unspecific EEG changes. An autopsy was performed. Brain neuropathology confirmed sporadic CJD (sCJD. Conclusions: CBS is a heterogeneous clinical syndrome whose differential diagnosis is extensive. CJD can occasionally present with clinical characteristics resembling CBS. MRI detection of abnormalities in some sequences (FLAIR, DWI, as previously reported, has high diagnostic utility for sCJD diagnosis – especially in early stages – when other tests can still appear normal. Abnormalities on DWI sequencing may not correlate with neuropathological findings, suggesting a functional basis to explain the changes found.

  1. Socio-economic status by rapid appraisal is highly correlated with mortality risks in rural Africa

    NARCIS (Netherlands)

    van Bodegom, D.; May, L.; Kuningas, M.; Kaptijn, R.; Thomese, G.C.F.; Meij, H.J.; Amankwa, J.; Westendorp, R.G.J.

    2009-01-01

    Socio-economic status is an important determinant of health and survival in rural Africa and necessitates a practical and valid instrument to implement in health studies. Our objective was to investigate the validity of the rapid appraisal method to assess socio-economic status and its ability to

  2. Economic impacts study

    Energy Technology Data Exchange (ETDEWEB)

    Brunsen, W.; Worley, W.; Frost, E.

    1988-09-30

    This is a progress report on the first phase of a project to measure the economic impacts of a rapidly changing U.S. target base. The purpose of the first phase is to designate and test the macroeconomic impact analysis model. Criteria were established for a decision-support model. Additional criteria were defined for an interactive macroeconomic impact analysis model. After a review of several models, the Economic Impact Forecast System model of the U.S. Army Construction Research Laboratory was selected as the appropriate input-output tool that can address local and regional economic analysis. The model was applied to five test cases to demonstrate its utility and define possible revisions to meet project criteria. A plan for EIFS access was defined at three levels. Objectives and tasks for scenario refinement are proposed.

  3. Human Mobility Analysis for Extracting Local Interactions under Rapid Socio-Economic Transformation in Dawei, Myanmar

    Directory of Open Access Journals (Sweden)

    Satomi Kimijima

    2017-09-01

    Full Text Available Understanding human mobility patterns provides knowledge about impacts of a socio-economic transformation in a rapidly urbanizing environment. This study assesses a long-term mobility data which uses a face-to-face questionnaire and GPS logger-based method of data collection for extracting socio-economic impacts from the rapid transformation. Conversion of mobility related information such as travel distance, direction, and time from the questionnaire survey into spatiotemporal information was carried out by developing an algorithm. To illustrate the proposed approach, a case study in Dawei Special Economic Zone, Myanmar was conducted. The results show that the questionnaire-based mobility data can be associated with GPS-based mobility data and diverse mobility patterns are found for different social groups in the stage of urban formation. The results enabled an understanding of the human dynamics in interactions, which can be used for monitoring rural sustainability and its challenges in the future with the background of the accelerated project development in the area.

  4. Development of a Conceptual Model of Disease Progression for Use in Economic Modeling of Chronic Obstructive Pulmonary Disease.

    Science.gov (United States)

    Tabberer, Maggie; Gonzalez-McQuire, Sebastian; Muellerova, Hana; Briggs, Andrew H; Rutten-van Mölken, Maureen P M H; Chambers, Mike; Lomas, David A

    2017-05-01

    To develop and validate a new conceptual model (CM) of chronic obstructive pulmonary disease (COPD) for use in disease progression and economic modeling. The CM identifies and describes qualitative associations between disease attributes, progression and outcomes. A literature review was performed to identify any published CMs or literature reporting the impact and association of COPD disease attributes with outcomes. After critical analysis of the literature, a Steering Group of experts from the disciplines of health economics, epidemiology and clinical medicine was convened to develop a draft CM, which was refined using a Delphi process. The refined CM was validated by testing for associations between attributes using data from the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE). Disease progression attributes included in the final CM were history and occurrence of exacerbations, lung function, exercise capacity, signs and symptoms (cough, sputum, dyspnea), cardiovascular disease comorbidities, 'other' comorbidities (including depression), body composition (body mass index), fibrinogen as a biomarker, smoking and demographic characteristics (age, gender). Mortality and health-related quality of life were determined to be the most relevant final outcome measures for this model, intended to be the foundation of an economic model of COPD. The CM is being used as the foundation for developing a new COPD model of disease progression and to provide a framework for the analysis of patient-level data. The CM is available as a reference for the implementation of further disease progression and economic models.

  5. Tc-99m-bicisate (ECD)-brain-SPECT in rapidly progressive dementia

    International Nuclear Information System (INIS)

    Marienhagen, J.; Eilles, C.; Weingaertner, U.; Blaha, L.; Zerr, I.; Poser, S.

    1999-01-01

    We present a 61-year-old male patient with progressive dementia. A brain SPECT with Tc-99m-bicisate was performed for confirmation of clinically suspected Alzheimer-dementia. At the time of the SPECT-investigation marked apraxia and aphasia besides severe dementia were present. Electrophysiological as well as anatomical neuroimaging findings showed non-diagnostic alterations. SPECT revealed distinct perfusion defects, which made Alzheimer Dementia unlikely. The further course of the patient was determined by rapidly progressive deterioration with development of akinetic mutism. Thereafter, increased levels of neuron-specific enolase as well as 14-3-3 proteins were found in the cerebro-spinal fluid (CSF). The patient finally died with signs of cerebral decortication. Due to the clinical course and the CSF-findings the patient's final diagnosis was Creutzfeld-Jakob-disease, nevertheless no autopsy was performed. The presented case report underscores the clinical utility of perfusion brain SPECT in the differential diagnosis of dementias. (orig.) [de

  6. Successful autologous hematopoietic stem cell transplantation for a patient with rapidly progressive localized scleroderma.

    Science.gov (United States)

    Nair, Velu; Sharma, Ajay; Sharma, Sanjeevan; Das, Satyaranjan; Bhakuni, Darshan S; Narayanan, Krishnan; Nair, Vivek; Shankar, Subramanian

    2015-03-01

    Autologous hematopoietic stem cell transplant (HSCT) for rapidly progressive disease has not been reported in localized scleroderma. Our patient, a 16-year-old girl had an aggressive variant of localized scleroderma, mixed subtype (linear-generalized) with Parry Romberg syndrome, with no internal organ involvement, that was unresponsive to immunosuppressive therapy and was causing rapid disfigurement. She was administered autologous HSCT in June 2011 and has maintained drug-free remission with excellent functional status at almost 3.5 years of follow-up. © 2015 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.

  7. Severe hyponatraemia with absence of hyperkalaemia in rapidly progressive Addison's disease.

    Science.gov (United States)

    Thompson, Michael D; Kalmar, Eileen; Bowden, Sasigarn A

    2015-05-28

    We present a case of rapidly progressing Addison's disease in adrenal crisis with severe hyponatraemia and absence of hyperkalaemia in a 10-year-old girl. She presented with 2 weeks of vomiting, fatigue and weight loss. Her serum electrolytes obtained 1 week prior to presentation were normal, except for mild hyponatraemia at 131 mmol/L, which dropped to 112 mmol/L on admission. She had normal serum potassium, low-serum osmolality, with elevated urine sodium and osmolality, indistinguishable from syndrome of inappropriate antidiuretic hormone (SIADH). Subsequently, Addison's disease was diagnosed on the basis of gingival hyperpigmentation and undetectable cortisol on adrenocorticotropic hormone stimulation test. She rapidly responded to stress dose hydrocortisone, followed by hydrocortisone and fludrocortisone replacement therapy. The absence of hyperkalaemia in the presence of severe hyponatraemia cannot rule out Addison's disease in children. The mechanism of hypo-osmolar hyponatraemia in primary adrenal insufficiency and clinical clues to differentiate it from SIADH are discussed. 2015 BMJ Publishing Group Ltd.

  8. Poorly differentiated ductal adenocarcinoma of the pancreas with rapid progression in a young man.

    Science.gov (United States)

    Tezuka, Koji; Ishiyama, Tomoharu; Takeshita, Akiko; Matsumoto, Hidekazu; Jingu, Akira; Kikuchi, Jiro; Yamaya, Hideyuki; Ohe, Rintaro; Ishizawa, Tetsuya

    2018-04-16

    Pancreatic cancer in young adults is very rare. We report a case of young-onset poorly differentiated pancreatic ductal adenocarcinoma with rapid progression and poor prognosis in a 31-year-old Japanese man with no obvious family history of malignancy. Preoperative examinations revealed a mass lesion in the body of the pancreas, accompanied by a slightly dilated main pancreatic duct distal to the mass lesion. Pancreatic cancer with acute pancreatitis was suspected because of an elevation of serum pancreatic enzyme and tumor marker, along with imaging findings. Distal pancreatectomy with resection of the common hepatic artery and splenectomy along with lymph node dissection was performed. Microscopically, the tumor was mainly composed of poorly differentiated ductal adenocarcinoma. The postoperative course was uneventful, but the patient had multiple liver metastases 2 months postoperatively, in spite of adjuvant chemotherapy, and died 8 months postoperatively. This case may represent a rare instance of young-onset poorly differentiated ductal adenocarcinoma with rapid progression and may indicate potential risk factors of pancreatic cancer in young adults.

  9. Biomedical Progress Rates as New Parameters for Models of Economic Growth in Developed Countries

    Directory of Open Access Journals (Sweden)

    Alex Zhavoronkov

    2013-11-01

    Full Text Available While the doubling of life expectancy in developed countries during the 20th century can be attributed mostly to decreases in child mortality, the trillions of dollars spent on biomedical research by governments, foundations and corporations over the past sixty years are also yielding longevity dividends in both working and retired population. Biomedical progress will likely increase the healthy productive lifespan and the number of years of government support in the old age. In this paper we introduce several new parameters that can be applied to established models of economic growth: the biomedical progress rate, the rate of clinical adoption and the rate of change in retirement age. The biomedical progress rate is comprised of the rejuvenation rate (extending the productive lifespan and the non-rejuvenating rate (extending the lifespan beyond the age at which the net contribution to the economy becomes negative. While staying within the neoclassical economics framework and extending the overlapping generations (OLG growth model and assumptions from the life cycle theory of saving behavior, we provide an example of the relations between these new parameters in the context of demographics, labor, households and the firm.

  10. Biomedical progress rates as new parameters for models of economic growth in developed countries.

    Science.gov (United States)

    Zhavoronkov, Alex; Litovchenko, Maria

    2013-11-08

    While the doubling of life expectancy in developed countries during the 20th century can be attributed mostly to decreases in child mortality, the trillions of dollars spent on biomedical research by governments, foundations and corporations over the past sixty years are also yielding longevity dividends in both working and retired population. Biomedical progress will likely increase the healthy productive lifespan and the number of years of government support in the old age. In this paper we introduce several new parameters that can be applied to established models of economic growth: the biomedical progress rate, the rate of clinical adoption and the rate of change in retirement age. The biomedical progress rate is comprised of the rejuvenation rate (extending the productive lifespan) and the non-rejuvenating rate (extending the lifespan beyond the age at which the net contribution to the economy becomes negative). While staying within the neoclassical economics framework and extending the overlapping generations (OLG) growth model and assumptions from the life cycle theory of saving behavior, we provide an example of the relations between these new parameters in the context of demographics, labor, households and the firm.

  11. Complicated acute appendicitis presenting as a rapidly progressive soft tissue infection of the abdominal wall: a case report.

    Science.gov (United States)

    Beerle, Corinne; Gelpke, Hans; Breitenstein, Stefan; Staerkle, Ralph F

    2016-12-01

    We report a case of a rare complication of acute appendicitis with perforation through the abdominal wall. The case points out that an intraabdominal origin should be considered in patients presenting with rapidly spreading soft tissue infections of the trunk. A 58-year-old European woman presented to our hospital with a 1-week history of severe abdominal pain accompanied by rapidly spreading erythema and emphysema of the lower abdomen. On admission, the patient was in septic shock with leukocytosis and elevation of C-reactive protein. Among other diagnoses, necrotizing fasciitis was suspected. Computed tomography showed a large soft tissue infection with air-fluid levels spreading through the lower abdominal wall. During the operation, we found a perforated appendicitis breaking through the fascia and causing a rapidly progressive soft tissue infection of the abdominal wall. Appendicitis was the origin of the soft tissue infection. The abdominal wall was only secondarily involved. Even though perforated appendicitis as an etiology of a rapidly progressive soft tissue infection of the abdominal wall is very rare, it should be considered in the differential diagnosis of abdominal wall cellulitis. The distinction between rapidly spreading subcutaneous infection with abscess formation and early onset of necrotizing fasciitis is often difficult and can be confirmed only by surgical intervention.

  12. Male patients presenting with rapidly progressive puberty associated with malignant tumors

    Directory of Open Access Journals (Sweden)

    Soo Jung Kim

    2016-03-01

    Full Text Available In males, precocious puberty (PP is defined as the development of secondary sexual characteristics before age 9 years. PP is usually idiopathic; though, organic abnormalities including tumors are more frequently found in male patients with PP. However, advanced puberty in male also can be an important clinical manifestation in tumors. We report 2 cases of rapidly progressive puberty in males, each associated with a germ-cell tumor. First, an 11-year-old boy presented with mild fever and weight loss for 1 month. Physical examination revealed a pubertal stage of G3P3 with 10-mL testes. Investigations revealed advanced bone age (16 years with elevated basal luteinizing hormone and testosterone levels. An anterior mediastinal tumor was identified by chest radiography and computed tomography, and elevated α-fetoprotein (AFP and β-human chorionic gonadotropin (β-hCG levels were noted. Histopathologic analysis confirmed a yolk-sac tumor. Second, a 12-year-old boy presented with diplopia, polydipsia, and polyuria for 4 months. Physical examination revealed a pubertal stage of G3P3 with 8-mL testes. Bone age was advanced (16 years and laboratory tests indicated panhypopituitarism with elevated testosterone level. A mixed germ-cell tumor was diagnosed with elevated AFP and β-hCG levels. Of course, these patients also have other symptoms of suspecting tumors, however, rapidly progressive puberty can be the more earlier screening sign of tumors. Therefore, in male patients with accelerated or advanced puberty, malignancy should be considered, with evaluation of tumor markers. In addition, advanced puberty in male should be recognized more widely as a unique sign of neoplasm.

  13. "Rekindle and Recapture the Love": Establishing System-Wide Indicators of Progress in Community Engagement and Economic Development

    Science.gov (United States)

    Janke, Emily M.

    2014-01-01

    In May 2012, University of North Carolina (UNC) President Tom Ross simultaneously commissioned two task forces to develop indicators that all UNC campuses could use to measure "progress in community engagement and economic development." The charge to the Community Engagement Task Force and the Economic Development Task Force was to…

  14. Plasmablastic myeloma presenting as rapidly progressive renal failure in a young adult

    Directory of Open Access Journals (Sweden)

    M Srija

    2014-01-01

    Full Text Available Multiple myeloma (MM is a condition where there is malignant proliferation of plasma cells. There is a strong correlation with age, peaking at 60-70 years. The clinical course in adolescents and young individuals is generally indolent and the survival is longer. We report a case of a 28-year-old male, who was diagnosed to have plasmablastic myeloma, an atypical variant of MM with a poor prognosis, presenting as rapidly progressive renal failure. He was given induction chemotherapy and then underwent autologous peripheral blood stem cell transplantation.

  15. Uruguay; Recent Economic Developments

    OpenAIRE

    International Monetary Fund

    1996-01-01

    This paper describes economic developments in Uruguay during the 1990s. Real GDP expanded on average by more than 4 percent a year in 1990–94 and fell by 2½ percent in 1995. The rapid growth of output during 1990–94 reflected buoyant external demand from Uruguay’s main trading partners (Argentina and Brazil), as well as progress in strengthening the public finances, reducing wage indexation, opening the economy, and curtailing government intervention. Consumer price inflation fell steadily fr...

  16. Rapid Progression of Metastatic Pulmonary Calcification and Alveolar Hemorrhage in a Patient with Chronic Renal Failure and Primary Hyperparathyroidism

    International Nuclear Information System (INIS)

    Yoon, Eun Joo; Kim, Dong Hun; Yoon, Seong Ho; Suk, Eun Ha

    2013-01-01

    Metastatic pulmonary calcification (MPC) is common in patients with chronic renal failure. The authors experienced a patient with chronic renal failure and primary hyperparathyroidism by parathyroid adenoma accompanied with rapid progressions of MPC and alveolar hemorrhage. Recent chest radiographs, compared with previous chest radiographs, showed rapid accumulation of calcification in both upper lungs. Following up on the high-resolution CT scan after five years demonstrates more increased nodules in size and ground glass opacity. The patient was diagnosed with MPC and alveolar hemorrhage by transbronchial lung biopsy. We assumed rapid progression of MPC and alveolar hemorrhage in underlying chronic renal failures could be a primary hyperparathyroidism which may be caused by parathyroid adenoma detected incidentally. Therefore parathyroid adenoma was treated with ethanol injections. Herein, we have reported on CT findings of MPC with alveolar hemorrhage and reviewed our case along with other articles.

  17. Research progress of socio-economic water cycle in China

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    China has made great progress in the study of socio-economic water cycle. She has completed national water resources appraisement and medium to long-term water supply planning. She has been engaging in study on water-deficient regions in North China and Northwest China for about half a century. For solving water shortage problem in northern China, she has put forward the famous South-to-North Water Transferring Projects, which has been set as one of the four biggest national projects in the Tenth Five-Year-Plan period although there are still debates. For promoting water use efficiency, China has been reforming her water management system, including water right system and water price system. There has already been a case of water right purchase. China has also done a lot of research on the interaction between human activity, water and ecosystem. For meeting the need of sustainability and coordinating water resources development and environmental protection, the study of ecological water requirement became very hot in recent years. There are three focuses of socio-economic water cycle study now in China: water transfer projects from the south to the north, water resources management and ecological water requirement.

  18. The impact of rapid economic growth and globalization on zinc nutrition in South Korea.

    Science.gov (United States)

    Kwun, In-Sook; Do, Mi-Sook; Chung, Hae-Rang; Kim, Yang Ha; Beattie, John H

    2009-08-01

    Zn deficiency may be widespread in Asian countries such as South Korea. However, dietary habits have changed in response to rapid economic growth and globalization. Zn nutrition in South Koreans has therefore been assessed during a period (1969-1998) of unprecedented economic growth. Cross-sectional food consumption data from the Korean National Nutrition Survey Reports (KNNSR) of South Korea at four separate time points (1969, 1978, 1988 and 1998) were used to calculate Zn, Ca and phytate intakes using various food composition tables, databases and literature values. Nutrient values in local foods were cited from their analysed values. Average Zn intake was 5.8, 4.8 and 5.3 mg/d for 1969, 1978 and 1988 respectively, increasing to 7.3 mg/d in 1998 (73 % of the Korean Dietary Reference Intake). The phytate:Zn molar ratio decreased from 21 to 8 during the study period. Dietary Zn depletion due to marked decreases in cereal consumption, particularly barley which has a low Zn bioavailability, was counterbalanced by marked increases in the consumption of meat and fish, which are also Zn-rich foods. Reduced phytate consumption coincident with increased Zn intake suggests that Zn bioavailability also improved, particularly by 1998. Although total Zn intake was not greatly affected over the initial period of economic growth in South Korea (1969-1988), Zn contributions from different food sources changed markedly and both Zn intake and potential bioavailability were improved by 1998. The study may have implications for Zn nutrition in other Asian countries currently experiencing rapid economic growth.

  19. Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons : the D:A:D study

    NARCIS (Netherlands)

    Kamara, David A; Ryom, Lene; Ross, Michael; Kirk, Ole; Reiss, Peter; Morlat, Philippe; Moranne, Olivier; Fux, Christoph A; Mocroft, Amanda; Sabin, Caroline; Lundgren, Jens D; Smith, Colette J; Schölvinck, Elisabeth H.

    2014-01-01

    BACKGROUND: No consensus exists on how to define abnormally rapid deterioration in renal function (Rapid Progression, RP). We developed an operational definition of RP in HIV-positive persons with baseline estimated glomerular filtration rate (eGFR) >90 ml/min/1.73 m2 (using Cockcroft Gault) in the

  20. Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons: the D:A:D study

    NARCIS (Netherlands)

    Kamara, David A.; Ryom, Lene; Ross, Michael; Kirk, Ole; Reiss, Peter; Morlat, Philippe; Moranne, Olivier; Fux, Christoph A.; Mocroft, Amanda; Sabin, Caroline; Lundgren, Jens D.; Smith, Colette J.; Powderly, B.; Shortman, N.; Moecklinghoff, C.; Reilly, G.; Franquet, X.; Ryom, L.; Sabin, C. A.; Kamara, D.; Smith, C.; Phillips, A.; Mocroft, A.; Tverland, J.; Mansfeld, M.; Nielsen, J.; Raben, D.; Lundgren, J. D.; Brandt, R. Salbøl; Rickenbach, M.; Fanti, I.; Krum, E.; Hillebregt, M.; Geffard, S.; Sundström, A.; Prins, J. M.; Kuijpers, T. W.; Scherpbier, H. J.; van der Meer, J. T. M.; Wit, F. W. M. N.; Godfried, M. H.; Nellen, F. J. B.; Lange, J. M. A.; Geerlings, S. E.; van Vugt, M.; Pajkrt, D.; Grijsen, M. L.; Wiersinga, W. J.; Goorhuis, A.; Hovius, J. W. R.

    2014-01-01

    No consensus exists on how to define abnormally rapid deterioration in renal function (Rapid Progression, RP). We developed an operational definition of RP in HIV-positive persons with baseline estimated glomerular filtration rate (eGFR) >90 ml/min/1.73 m2 (using Cockcroft Gault) in the Data

  1. Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons: the D:A:D study

    NARCIS (Netherlands)

    Kamara, D.A.; Ryom, L.; Ross, M.; Kirk, O.; Reiss, P.; Morlat, P.; Moranne, O.; Fux, C.A.; Mocroft, A.; Sabin, C.; Lundgren, J.D.; Smith, C.J.; Koopmans †, P.P.; Keuter, M.; Ven, A.J.A.M. van der; Hofstede, H.J.M. ter; Dofferhoff, A.S.M.; Warris, A.; Crevel, R. van; et al.,

    2014-01-01

    BACKGROUND: No consensus exists on how to define abnormally rapid deterioration in renal function (Rapid Progression, RP). We developed an operational definition of RP in HIV-positive persons with baseline estimated glomerular filtration rate (eGFR) >90 ml/min/1.73 m2 (using Cockcroft Gault) in the

  2. Water Quality Changes during Rapid Urbanization in the Shenzhen River Catchment: An Integrated View of Socio-Economic and Infrastructure Development

    Directory of Open Access Journals (Sweden)

    Hua-peng Qin

    2014-10-01

    Full Text Available Surface water quality deterioration is a serious problem in many rapidly urbanizing catchments in developing countries. There is currently a lack of studies that quantify water quality variation (deterioration or otherwise due to both socio-economic and infrastructure development in a catchment. This paper investigates the causes of water quality changes over the rapid urbanization period of 1985–2009 in the Shenzhen River catchment, China and examines the changes in relation to infrastructure development and socio-economic policies. The results indicate that the water quality deteriorated rapidly during the earlier urbanization stages before gradually improving over recent years, and that rapid increases in domestic discharge were the major causes of water quality deterioration. Although construction of additional wastewater infrastructure can significantly improve water quality, it was unable to dispose all of the wastewater in the catchment. However, it was found that socio-economic measures can significantly improve water quality by decreasing pollutant load per gross regional production (GRP or increasing labor productivity. Our findings suggest that sustainable development during urbanization is possible, provided that: (1 the wastewater infrastructure should be constructed timely and revitalized regularly in line with urbanization, and wastewater treatment facilities should be upgraded to improve their nitrogen and phosphorus removal efficiencies; (2 administrative regulation policies, economic incentives and financial policies should be implemented to encourage industries to prevent or reduce the pollution at the source; (3 the environmental awareness and education level of local population should be increased; (4 planners from various sectors should consult each other and adapt an integrated planning approach for socio-economic and wastewater infrastructure development.

  3. Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases

    Directory of Open Access Journals (Sweden)

    Hai-yang JIANG

    2017-10-01

    Full Text Available Rapid eye movement sleep behavior disorder (RBD is a sleep disorder characterized by the disappearance of muscle relaxation and enacting one's dreams during rapid eye movement (REM, with most of the dreams being violent or aggressive. Prevalence of RBD, based on population, is 0.38%-2.01%, but it becomes much higher in patients with neurodegenerative diseases, especially α - synucleinopathies. RBD may herald the emergence of α-synucleinopathies by decades, thus it may be used as an effective early marker of neurodegenerative diseases. In this review, we summarized the progress on the pathogenesis of RBD and its relationship with neurodegenerative diseases. DOI: 10.3969/j.issn.1672-6731.2017.10.003

  4. Economic Benefit from Progressive Integration of Scheduling and Control for Continuous Chemical Processes

    Directory of Open Access Journals (Sweden)

    Logan D. R. Beal

    2017-12-01

    Full Text Available Performance of integrated production scheduling and advanced process control with disturbances is summarized and reviewed with four progressive stages of scheduling and control integration and responsiveness to disturbances: open-loop segregated scheduling and control, closed-loop segregated scheduling and control, open-loop scheduling with consideration of process dynamics, and closed-loop integrated scheduling and control responsive to process disturbances and market fluctuations. Progressive economic benefit from dynamic rescheduling and integrating scheduling and control is shown on a continuously stirred tank reactor (CSTR benchmark application in closed-loop simulations over 24 h. A fixed horizon integrated scheduling and control formulation for multi-product, continuous chemical processes is utilized, in which nonlinear model predictive control (NMPC and continuous-time scheduling are combined.

  5. Progress on PRISM, an inherently safe, economic, and testable advanced liquid metal reactor

    International Nuclear Information System (INIS)

    Tippets, F.E.; Salerno, L.N.; Boardman, C.E.; Kwant, W.; Murata, R.E.; Snyder, C.R.

    1987-01-01

    This paper reports progress on the design of PRISM (Power Reactor Inherently Safe Module) under the DOE-sponsored innovative reactor program now in its third year at General Electric. The purpose of this program is to develop a design for an inherently safe, reliable, and marketable liquid metal fast reactor power plant. The PRISM design approach includes the following key elements: Compact sodium-cooled pool-type reactor modules that are sized to enable factory fabrication, economical shipment to inland as well as water-side sites, and economical full-scale prototype testing for design certification; Nuclear safety-related envelope limited to the reactor modules and their service systems; Inherent, passive shutdown heat removal for loss-of-cooling events; Inherent, passive reactivity shutdown for failure-to-scram events

  6. THE PROGRESS OF ECONOMIC THOUGHTFULNESS CONCERNING THE SERVICES

    Directory of Open Access Journals (Sweden)

    CIOBAN Gabriela-Liliana

    2014-07-01

    production processes and the use of high level technologies will lead towards the growth f production level and the living standards of people. For the time being, one can characterize the economies of the developed countries and of many countries in progress of development, as being services oriented economies; the development and diversification of services was determined by the need of satisfying social needs, more and more diversified. In this way, the part of services aimed to become proportionally to their contribution, as regards the economic growth.

  7. On Rural Financial and Accounting Work under the Background of Rapid Agricultural Economic Development

    OpenAIRE

    Tang, Yaozheng

    2013-01-01

    Under the background of rapid agricultural economic development, rural financial and accounting work is of great significance. From rural accounting management system, rural accountant allocation and rural accounting training, this paper analyzes current situations of rural accounting work in China. In rural financial and accounting work, there are following problems. (1) Accounting behavior is not standard, and basic accounting work is to be further strengthened; (2) Internal control is not ...

  8. Economic growth and health progress in England and Wales: 160 years of a changing relation.

    Science.gov (United States)

    Tapia Granados, José A

    2012-03-01

    Using data for England and Wales during the years 1840-2000, a negative relation is found between economic growth--measured by the rate of growth of gross domestic product (GDP)--and health progress--as indexed by the annual increase in life expectancy at birth (LEB). That is, the lower is the rate of growth of the economy, the greater is the annual increase in LEB for both males and females. This effect is much stronger, however, in 1900-1950 than in 1950-2000, and is very weak in the 19th century. It appears basically at lag zero, though some short-lag effects of the same negative sign are found. In the other direction of causality, there are very small effects of the change in LEB on economic growth. These results add to an emerging consensus that in the context of long-term declining trends, mortality oscillates procyclically during the business cycle, declining faster in recessions. Therefore, LEB increases faster during recessions than during expansions. The investigation also shows how the relation between economic growth and health progress changed in England and Wales during the study period. No evidence of cointegration between income--as indexed by GDP or GDP per capita--and health--as indexed by LEB--is found. Copyright © 2012 Elsevier Ltd. All rights reserved.

  9. Chronic Family Economic Hardship, Family Processes and Progression of Mental and Physical Health Symptoms in Adolescence

    Science.gov (United States)

    Lee, Tae Kyoung; Wickrama, K. A. S.; Simons, Leslie Gordon

    2013-01-01

    Research has documented the relationship between family stressors such as family economic hardship and marital conflict and adolescents' mental health symptoms, especially depressive symptoms. Few studies, however, have examined the processes whereby supportive parenting lessens this effect and the progression of mental health and physical health…

  10. REVENUE FROM EXPORTING OIL, INCOME DISTRIBUTION, AND ECONOMIC PROGRESS IN THE MIDDLE EAST

    Directory of Open Access Journals (Sweden)

    Mehdi MOHAGHEGH

    2009-07-01

    Full Text Available The increases in petrodollars received by oil produ cing countries of the Middle East in the past few years can become a reality again when the wo rld economy recovers from this recession. The access to so much hard currency in the past co uld have potentially impr oved the economies of these nations beyond imagination. Economic de velopment specialists regard reaching some goals such as higher growth rate of real output, less chronic inflation, Improvements in education and healthcare services, greater diversity in the economy and in exports, greater equality in the distribution of income, and lower unemployment rate as indication of economic progress or socio –economic improvements in a developing country. The purpose of this paper is to evaluate the relative success of the Oil-Produc ing Countries of the Middle East in achieving the above socio- economic goals within the context of huge inflows of petrodollars into their countries every year. Through analysis of data from the region the author of this paper has obtained convincing evidence in support of the view that the oil-exporting nations have, for the most part, wasted the abundant and extremely valuable foreign curr encies that they have received every year for the past several decades.

  11. An unusual case of rapidly progressive contractures: Case report and brief review

    Directory of Open Access Journals (Sweden)

    Subasree R

    2008-01-01

    Full Text Available An 8-year-old boy, diagnosed as cervical dystonia, was referred to our tertiary center. After a trivial trauma he had developed painful lumps in the axial region, which was followed by restricted movements of neck, shoulder, and abdominal muscles over 4 months. He had kyphoscoliosis, torticollis, rigid abdomen, and multiple muscle contractures. He also had short great toes. A detailed skeletal survey showed calcification in the soft tissues surrounding the shoulder anterior chest wall, thorax, and paraspinal muscles; there was also beaking of vertebrae, which was confirmed by CT thorax. This report showcases the diagnostic challenge posed by myositis ossificans progressiva, which can rarely cause rapidly progressing muscle contractures. A brief review of literature is also presented.

  12. Democratization of Education as Prerequisite for Social Economic and Cultural Progress in a Multi-Cultural Society

    Science.gov (United States)

    Madumere, S. C.; Olisaemeka, B. U.

    2011-01-01

    This paper focuses on democratization of education as a prerequisite for social, economic and cultural progress in a multi-cultural society, such as Nigeria. Attempt was made to define and explain the major concepts in the paper. Education was explained as an instrument of democracy and as function of socialization, culture and economic…

  13. Rapidly progressive cryptogenic organising pneumonia presenting as a lung mass

    Science.gov (United States)

    Akram, Saeed; Irfan, Muhammad; Aftab, Kanwal

    2009-01-01

    A very rare case of a rapidly progressive variant of cryptogenic organising pneumonia (COP) presenting as a focal mass-like lesion with compression of the large airways leading to respiratory failure is described. A 60-year-old lady presented to the Aga Khan University Hospital Emergency Department in hypoxaemic respiratory failure with a 6-day history of dyspnoea, productive cough and fever. Chest x ray showed a right upper lobe mass-like lesion compressing the large airways and right pleural effusion. She deteriorated in the Emergency Department and was intubated due to worsening hypoxaemic respiratory failure. The pleural fluid and bronchoscopic specimens were negative on microbiological and cytological examination. CT-guided right lung biopsy revealed chronic non-specific inflammation without granuloma and malignancy. COP was diagnosed on video-assisted thoracoscopic (VATS) lung biopsy. She was successfully treated with high dose steroids and discharged in a stable condition; her 3-month follow-up chest x rays showed complete resolution of the lung lesion with some residual fibrosis. PMID:21686529

  14. SOCIAL INEQUALITY IN CHINA AS A RESULT OF THE RAPID ECONOMIC GROWTH

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    Вероника Игоревна Шехурдина

    2013-12-01

    Full Text Available Since the period of openness in China, laid the foundation for more than 30 years ago, he has made remarkable progress in increasing incomes and reducing absolute poverty. However, they are caused by rising inequality. It should be noted that the rise in inequality was seen almost everywhere in the world over the past two decades. Growing dissatisfaction with the quality of economic growth is often seen in favor of certain groups more than the general population. This is clearly reflected in the growth of inequality between different groups - the rich are getting richer faster than the poor. The economic literature attributes this mainly to globalization, technological change, skills-based, and reduce the "power" of the workers. Growth model, which accompanies the last three decades to China, included a trade-off between high growth (and subsequent reduction of absolute poverty and worsening inequality. The government of China has recognized this problem and taken active steps to reduce the gap incomes and standards of living in the city and rural areas, which have already brought the first results.DOI: http://dx.doi.org/10.12731/2218-7405-2013-10-16

  15. Juvenile myopia progression, risk factors and interventions.

    Science.gov (United States)

    Myrowitz, Elliott H

    2012-07-01

    The development and progression of early onset myopia is actively being investigated. While myopia is often considered a benign condition it should be considered a public health problem for its visual, quality of life, and economic consequences. Nearly half of the visually impaired population in the world has uncorrected refractive errors, with myopia a high percent of that group. Uncorrected visual acuity should be screened for and treated in order to improve academic performance, career opportunities and socio-economic status. Genetic and environmental factors contribute to the onset and progression of myopia. Twin studies have supported genetic factors and research continues to identify myopia genetic loci. While multiple myopia genetic loci have been identified establishing myopia as a common complex disorder, there is not yet a genetic model explaining myopia progression in populations. Environmental factors include near work, education levels, urban compared to rural location, and time spent outdoors. In this field of study where there continues to be etiology controversies, there is recent agreement that children who spend more time outdoors are less likely to become myopic. Worldwide population studies, some completed and some in progress, with a common protocol are gathering both genetic and environmental cohort data of great value. There have been rapid population changes in prevalence rates supporting an environmental influence. Interventions to prevent juvenile myopia progression include pharmacologic agents, glasses and contact lenses. Pharmacological interventions over 1-2 year trials have shown benefits. Peripheral vision defocus has been found to affect the emmetropization process and may be affected by wearing glasses or contacts. Accommodation accuracy also has been implicated in myopia progression. Further research will aim to assess both the role and interaction of environmental influences and genetic factors.

  16. Information Loss from Technological Progress

    International Nuclear Information System (INIS)

    Townsend, P D

    2014-01-01

    Progress in electronics and optics offers faster computers, and rapid communication via the internet that is matched by ever larger and evolving storage systems. Instinctively one assumes that this must be totally beneficial. However advances in software and storage media are progressing in ways which are frequently incompatible with earlier systems and the economics and commercial pressures rarely guarantee total compatibility with earlier systems. Instead, the industries actively choose to force the users to purchase new systems and software. Thus we are moving forward with new technological variants that may have access to only the most recent systems and we will have lost earlier alternatives. The reality is that increased processing speed and storage capacity are matched by an equally rapid decline in the access and survival lifetime of older information. This pattern is not limited to modern electronic systems but is evident throughout history from writing on stone and clay tablets to papyrus and paper. It is equally evident in image systems from painting, through film, to magnetic tapes and digital cameras. In sound recording we have variously progressed from wax discs to vinyl, magnetic tape and CD formats. In each case the need for better definition and greater capacity has forced the earlier systems into oblivion. Indeed proposed interactive music systems could similarly relegate music CDs to specialist collections. The article will track some of the examples and discuss the consequences as well as noting that this information loss is further compounded by developments in language and changes in cultural views of different societies

  17. Information Loss from Technological Progress

    Science.gov (United States)

    Townsend, P. D.

    2014-12-01

    Progress in electronics and optics offers faster computers, and rapid communication via the internet that is matched by ever larger and evolving storage systems. Instinctively one assumes that this must be totally beneficial. However advances in software and storage media are progressing in ways which are frequently incompatible with earlier systems and the economics and commercial pressures rarely guarantee total compatibility with earlier systems. Instead, the industries actively choose to force the users to purchase new systems and software. Thus we are moving forward with new technological variants that may have access to only the most recent systems and we will have lost earlier alternatives. The reality is that increased processing speed and storage capacity are matched by an equally rapid decline in the access and survival lifetime of older information. This pattern is not limited to modern electronic systems but is evident throughout history from writing on stone and clay tablets to papyrus and paper. It is equally evident in image systems from painting, through film, to magnetic tapes and digital cameras. In sound recording we have variously progressed from wax discs to vinyl, magnetic tape and CD formats. In each case the need for better definition and greater capacity has forced the earlier systems into oblivion. Indeed proposed interactive music systems could similarly relegate music CDs to specialist collections. The article will track some of the examples and discuss the consequences as well as noting that this information loss is further compounded by developments in language and changes in cultural views of different societies.

  18. A Simple Diet- and Chemical-Induced Murine NASH Model with Rapid Progression of Steatohepatitis, Fibrosis and Liver Cancer.

    Science.gov (United States)

    Tsuchida, Takuma; Lee, Youngmin A; Fujiwara, Naoto; Ybanez, Maria; Allen, Brittany; Martins, Sebastiao; Fiel, M Isabel; Goossens, Nicolas; Chou, Hsin-I; Hoshida, Yujin; Friedman, Scott L

    2018-03-20

    Although the majority of patients with nonalcoholic fatty liver disease (NAFLD) have only steatosis without progression, a sizable fraction develop non-alcoholic steatohepatitis (NASH), which can lead to cirrhosis and hepatocellular carcinoma (HCC). Many established diet-induced mouse models for NASH require 24-52 weeks, which makes testing for drug response costly and time consuming. We have sought to establish a murine NASH model with rapid progression of extensive fibrosis and HCC by using a western diet (WD), which is high-fat, high-fructose and high-cholesterol, combined with low dose weekly intraperitoneal carbon tetrachloride (CCl 4 ), which served as an accelerator. C57BL/6J mice were fed a normal chow diet (ND) ± CCl 4 or WD ± CCl 4 for 12 and 24 weeks. Addition of CCl 4 exacerbated histological features of NASH, fibrosis, and tumor development induced by WD, which resulted in stage 3 fibrosis at 12 weeks and HCC development at 24 weeks. Furthermore, whole liver transcriptomic analysis indicated that dysregulated molecular pathways in WD/CCl 4 mice and immunologic features were closely similar to those of human NASH. Our mouse NASH model exhibits rapid progression of advanced fibrosis and HCC, and mimics histological, immunological and transcriptomic features of human NASH, suggesting that it will be a useful experimental tool for preclinical drug testing. A carefully characterized model has been developed in mice that recapitulates the progressive stages of human fatty liver disease, from simple steatosis, to inflammation, fibrosis and cancer. The functional pathways of gene expression and immune abnormalities in this model closely resemble human disease. The ease and reproducibility of this model makes it ideal to study disease pathogenesis and test new treatments. Copyright © 2018 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

  19. The Economic and Clinical Impact of Sustained Use of a Progressive Mobility Program in a Neuro-ICU.

    Science.gov (United States)

    Hester, Jeannette M; Guin, Peggy R; Danek, Gale D; Thomas, Jaime R; Titsworth, William L; Reed, Richard K; Vasilopoulos, Terrie; Fahy, Brenda G

    2017-06-01

    To investigate a progressive mobility program in a neurocritical care population with the hypothesis that the benefits and outcomes of the program (e.g., decreased length of stay) would have a significant positive economic impact. Retrospective analysis of economic and clinical outcome data before, immediately following, and 2 years after implementation of the Progressive Upright Mobility Protocol Plus program (UF Health Shands Hospital, Gainesville, FL) involving a series of planned movements in a sequential manner with an additional six levels of rehabilitation in the neuro-ICU at UF Health Shands Hospital. Thirty-bed neuro-ICU in an academic medical center. Adult neurologic and neurosurgical patients: 1,118 patients in the pre period, 731 patients in the post period, and 796 patients in the sustained period. Implementation of Progressive Upright Mobility Protocol Plus. ICU length of stay decreased from 6.5 to 5.8 days in the immediate post period and 5.9 days in the sustained period (F(2,2641) = 3.1; p = 0.045). Hospital length of stay was reduced from 11.3 ± 14.1 days to 8.6 ± 8.8 post days and 8.8 ± 9.3 days sustained (F(2,2641) = 13.0; p mobility program in the neurocritical care population has clinical and financial benefits associated with its implementation and should be considered.

  20. Some Approaches to the Accounting and Analysis of the Impact of Scientific and Technological Progress in the Harrod-Domar Economic Growth Model

    Directory of Open Access Journals (Sweden)

    Dilenko Viktor O.

    2016-11-01

    Full Text Available The paper presents methods for the accounting of autonomous and induced scientific and technological progress in the Harrod-Domar model of economic dynamics that imply determining the incremental capital/output ratio of the model in the form of special functions of time. As part of the received version of the Harrod-Domar model, on the basis of conditional data there conducted a numerical study of some aspects of the impact of parameters of scientific and technological progress and the initial state of the economy being modeled on peculiarities of corresponding trajectories of its dynamics. A simple economic and mathematical problem of determining an optimal value of investments in the implementation of the induced STP is formulated, and content interpretation of the obtained solution is carried out. Possible directions of development of the obtained results may be associated with the application of the proposed modification of the Harrod-Domar model to build and analyze mathematical models of optimal economic growth in view of the induced STP, as well as with the prospective use of these results to improve dynamic models of the Leontief type in terms of considering innovation processes (scientific and technical progress of various kinds.

  1. Rapidly progressive polyneuropathy due to dry beriberi in a man: a case report

    Directory of Open Access Journals (Sweden)

    Lekwuwa Godwin

    2010-12-01

    Full Text Available Abstract Introduction We describe a case of rapidly progressive and severely debilitating polyneuropathy in a patient with confirmed hypovitaminosis B1, consistent with dry beriberi. Crucially, this is a treatable condition, although sometimes with incomplete recovery, but it is probably under-recognized yet increasingly common given increasing levels of alcohol abuse in the western world. Case presentation A 49-year-old Caucasian British man presented with progressive weakness of both lower limbs of approximately seven months' duration. He noted difficulty climbing stairs. He also complained of lethargy, and loss of muscle bulk, including his thighs. He had a history of type 2 diabetes mellitus and admitted prior alcohol abuse but denied excessive alcohol intake in the five years prior to presentation. Initial clinical and neurophysiological examinations were consistent with a mild peripheral neuropathy and probable proximal myopathy. However, over the subsequent four months he evolved a marked tetraparesis, with profound sensory disturbance of all limbs. Repeat neurophysiology revealed a widespread polyneuropathy with extensive acute and sub-acute denervation changes in all four limbs, and reduced or absent sensory nerve action potentials. Hypovitaminosis B1 was confirmed (45 nmol/L, reference range 66-200 nmol/L. His rapid clinical deterioration was in keeping with dry beriberi. He was treated with thiamine. Subsequent follow-up revealed slow but significant improvement, such that by 15-16 months from the initial onset of symptoms, and approximately six months after the onset of his marked tetraparesis, he was able to stand independently and was gradually gaining confidence in walking pending a period of in-patient neurorehabilitation. Conclusion A potentially wide differential diagnosis exists for this type of presentation. Confirming hypovitaminosis B1 by requesting the assay prior to vitamin replacement ensures accurate diagnosis and

  2. Peranan Terapi Awal dan Terapi Pemeliharaan pada Rapidly Progressive Periodontitis Type 1

    Directory of Open Access Journals (Sweden)

    Anita H. Joedo

    2015-08-01

    Full Text Available Rapidly Progressive Periodontitis (RPP is a severe form of a periodontal disease which starts since a puberty age. The disease if a generalized periodontal destruction without a specific distribution mode: it develops more progressively but does not in accordance to local factors. The first step to the RPP treatment is initial therapy: i.e. DHE, scaling and root planing, and eliminating predisposing local factors and continued with a maintence therapy which will support the success of a surgery later. A study case: a 21-year old RPP woman showed hyperaemia, an abscess, a 10 mm mesial pocket depth, a 5 mm distal pocker depth, a 5 mm buccal pocket depth, a 2nd degree tooth mobility and a 3 mm buccal recession on 25. In the initial therapy she was given an amoxicillin, a metronidazole for killing a supra and subgingival baterial, vitamins B and C, and also a chlorhexidine 0.2% mouth wash for a week. After a week the abscess and the inflammation decreased, but the mobility was still in the same condition and the DHE was still evaluated because of the patient's social factor, the FO was delayed. The next visit was done every 2 monts for a year for maintenance care. The clinical result showed the gingival inflammation and the tooth mobility disappeared. Radiographically, the alveolar bone showed more radiopaque and the lamina dura was seen. In conclusio, the initial and the maintenance therapy was seen to heal the RPP.

  3. Safe communities in China as a strategy for injury prevention and safety promotion programmes in the era of rapid economic growth.

    Science.gov (United States)

    Wang, Shu-Mei; Dalal, Koustuv

    2013-02-01

    Due to its rapid economic development, China is facing a huge health, social, and economic burden resulting from injuries. The study's objective was to examine Safe Communities in China as a strategy for injury prevention and safety promotion programmes in the era of rapid economic growth. Literature searches in English and Chinese, which included grey literature, were performed on the Chinese Journal Full-text Search System and Medline, using the words "Safe Community", "injury", "economics", and "prevention". The results showed that the existing 35 recognized members of the International Safe Community Network have not placed due emphasis on suicide prevention, which is one of the leading problems in both rural and urban China. A few groups, such as children, the elderly, cyclists, and pedestrians, have received due emphasis, while other vulnerable groups, such as migrant workers, motorcyclists, students, players, and farmers have not received the necessary attention from the Safe Community perspective. As the evidence describes, Safe Communities in China can be a very effective strategy for injury prevention, but four aspects need to be strengthened in the future: (1) establish and strengthen the policy and regulations in terms of injury prevention at the national level; (2) create a system to involve professional organizations and personnel in projects; (3) consider the economic development status of different parts of China; and (4) intentional injury prevention should receive greater attention.

  4. Rapidly Progressive Osteoarthritis: a Review of the Clinical and Radiologic Presentation.

    Science.gov (United States)

    Flemming, Donald J; Gustas-French, Cristy N

    2017-07-01

    The purpose of this paper is to review the distinct clinical and radiographic features that may lead to prompt diagnosis of rapidly progressive osteoarthritis (RPOA) and thus obviate unnecessary and costly diagnostic workup. RPOA is uncommon but is more frequently seen in practice because of the aging population. RPOA is a destructive arthropathy that occurs most commonly in elderly women but can also be seen in patients that have sustained trauma. The dramatic radiologic manifestations of RPOA can lead to diagnostic confusion with other arthropathies, infection, and osteonecrosis. RPOA was originally described in the hip but may also involve the shoulder. The etiology of RPOA is not well understood, but subchondral fracture probably plays a role in the development of dramatic destruction of the joint that is seen in affected patients. Early diagnosis may reduce the complexity of surgical management. RPOA is an uncommon condition that occurs most frequently in elderly woman or in patients who have sustained trauma. Prompt recognition of the clinical and radiologic features of this arthropathy can reduce unnecessary diagnostic workup and complexity of surgical intervention.

  5. Economic impact of rapid diagnostic methods in Clinical Microbiology: Price of the test or overall clinical impact.

    Science.gov (United States)

    Cantón, Rafael; Gómez G de la Pedrosa, Elia

    2017-12-01

    The need to reduce the time it takes to establish a microbiological diagnosis and the emergence of new molecular microbiology and proteomic technologies has fuelled the development of rapid and point-of-care techniques, as well as the so-called point-of-care laboratories. These laboratories are responsible for conducting both techniques partially to response to the outsourcing of the conventional hospital laboratories. Their introduction has not always been accompanied with economic studies that address their cost-effectiveness, cost-benefit and cost-utility, but rather tend to be limited to the unit price of the test. The latter, influenced by the purchase procedure, does not usually have a regulated reference value in the same way that medicines do. The cost-effectiveness studies that have recently been conducted on mass spectrometry in the diagnosis of bacteraemia and the use of antimicrobials have had the greatest clinical impact and may act as a model for future economic studies on rapid and point-of-care tests. Copyright © 2017 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  6. A rapid, efficient, and economic device and method for the isolation and purification of mouse islet cells.

    Directory of Open Access Journals (Sweden)

    Yin Zongyi

    Full Text Available Rapid, efficient, and economic method for the isolation and purification of islets has been pursued by numerous islet-related researchers. In this study, we compared the advantages and disadvantages of our developed patented method with those of commonly used conventional methods (Ficoll-400, 1077, and handpicking methods. Cell viability was assayed using Trypan blue, cell purity and yield were assayed using diphenylthiocarbazone, and islet function was assayed using acridine orange/ethidium bromide staining and enzyme-linked immunosorbent assay-glucose stimulation testing 4 days after cultivation. The results showed that our islet isolation and purification method required 12 ± 3 min, which was significantly shorter than the time required in Ficoll-400, 1077, and HPU groups (34 ± 3, 41 ± 4, and 30 ± 4 min, respectively; P 1000 islets. In summary, the MCT method is a rapid, efficient, and economic method for isolating and purifying murine islet cell clumps. This method overcomes some of the shortcomings of conventional methods, showing a relatively higher quality and yield of islets within a shorter duration at a lower cost. Therefore, the current method provides researchers with an alternative option for islet isolation and should be widely generalized.

  7. Rapid and economical data acquisition in ultrafast frequency-resolved spectroscopy using choppers and a microcontroller.

    Science.gov (United States)

    Guo, Liang; Monahan, Daniele M; Fleming, Graham

    2016-08-08

    Spectrometers and cameras are used in ultrafast spectroscopy to achieve high resolution in both time and frequency domains. Frequency-resolved signals from the camera pixels cannot be processed by common lock-in amplifiers, which have only a limited number of input channels. Here we demonstrate a rapid and economical method that achieves the function of a lock-in amplifier using mechanical choppers and a programmable microcontroller. We demonstrate the method's effectiveness by performing a frequency-resolved pump-probe measurement on the dye Nile Blue in solution.

  8. Energy abundance and economic progress

    International Nuclear Information System (INIS)

    Schurr, S.H.

    1983-01-01

    A discussion is presented on the benefits of energy abundance and on the links between energy supply, economic growth and human welfare in the United States. It is argued that the restoration of energy abundance with dependable sources of supply should be a major national objective. (U.K.)

  9. A CONCEPTUAL APPROACH TO ECONOMIC AGGLOMERATIONS

    Directory of Open Access Journals (Sweden)

    Mădălina-Ștefania Dîrzu

    2012-09-01

    Full Text Available Technological progress and rapid structural adjustments have characterized a lot of economies in the last century and they still feature pronounced structures. An important observation is that economic activities tend to agglomerate in space as a result of some kind increasing returns, forming eventually economic agglomerations. When various companies gather together, they establish specific forms of interaction. Increasing returns produce when this mutual interplay creates positive externalities for those firms which operate into an agglomeration. In this context, it is crucial to raise a question: what is an economic agglomeration and what do different scientists imply when using the concept? The phenomenon of agglomeration has attracted researchers from various disciplines employing a hybrid set of analytical perspectives. This whole framework is still puzzled with contradictory conceptualizations which are often used in an ambiguous way. Scientists tend to utilize notions such as agglomeration, cluster, territorial network, specialization, concentration somewhat interchangeably and with little concern about how to operationalize them. To shed a light on this issue, the aim of this paper is to provide a comprehensive analyze of different theoretical framework in which economic agglomerations have been debated and researched.

  10. Natural Resources and Socio-Economic Progress

    Directory of Open Access Journals (Sweden)

    Larissa Mikhaylovna Kapitsa

    2014-01-01

    Full Text Available The article reviews international debates on development problems of the resource-based economies. It draws atten tion to causes and mechanisms of the so-called "resource curse" and symptoms of systemic breakdowns and stagnant phenomena in resource-based economies named "Dutch disease". Specific attention is given to the role of national elites and institutions in the emergence of "Dutch disease", preservation of economic backwardness and/or de-industrialization of resource-rich countries. The author also considers new approaches to resolving the problem of'resource-curse", in particular, return to traditional instruments of economic diversification as industrialization and protectionism.

  11. INCOME INEQUALITY AND ECONOMIC GROWTH: THE CASE OF INDIAN STATES 1980-2009-10

    Directory of Open Access Journals (Sweden)

    Ross Stewart

    2012-06-01

    Full Text Available Beginning in the 1980s, India has experienced an acceleration of economic growth by way of a promotion of a more efficient pro business and market oriented model. Following the rapid growth of the 1980s, the 1990s brought continued deregulation through market liberalization policies and additional progressive strides by way of a financial crisis in the spring of 1991. These happenings and others have had significant impacts on India's income inequality; therefore, this study endeavors to investigate primarily the relationship between income inequality and economic growth, while surveying other relevant macroeconomic variables.

  12. CRF19_cpx is an Evolutionary fit HIV-1 Variant Strongly Associated With Rapid Progression to AIDS in Cuba.

    Science.gov (United States)

    Kouri, Vivian; Khouri, Ricardo; Alemán, Yoan; Abrahantes, Yeissel; Vercauteren, Jurgen; Pineda-Peña, Andrea-Clemencia; Theys, Kristof; Megens, Sarah; Moutschen, Michel; Pfeifer, Nico; Van Weyenbergh, Johan; Pérez, Ana B; Pérez, Jorge; Pérez, Lissette; Van Laethem, Kristel; Vandamme, Anne-Mieke

    2015-03-01

    Clinicians reported an increasing trend of rapid progression (RP) (AIDS within 3 years of infection) in Cuba. Recently infected patients were prospectively sampled, 52 RP at AIDS diagnosis (AIDS-RP) and 21 without AIDS in the same time frame (non-AIDS). 22 patients were sampled at AIDS diagnosis (chronic-AIDS) retrospectively assessed as > 3 years infected. Clinical, demographic, virological, epidemiological and immunological data were collected. Pol and env sequences were used for subtyping, transmission cluster analysis, and prediction of resistance, co-receptor use and evolutionary fitness. Host, immunological and viral predictors of RP were explored through data mining. Subtyping revealed 26 subtype B strains, 6 C, 6 CRF18_cpx, 9 CRF19_cpx, 29 BG-recombinants and other subtypes/URFs. All patients infected with CRF19 belonged to the AIDS-RP group. Data mining identified CRF19, oral candidiasis and RANTES levels as the strongest predictors of AIDS-RP. CRF19 was more frequently predicted to use the CXCR4 co-receptor, had higher fitness scores in the protease region, and patients had higher viral load at diagnosis. CRF19 is a recombinant of subtype D (C-part of Gag, PR, RT and nef), subtype A (N-part of Gag, Integrase, Env) and subtype G (Vif, Vpr, Vpu and C-part of Env). Since subtypes D and A have been associated with respectively faster and slower disease progression, our findings might indicate a fit PR driving high viral load, which in combination with co-infections may boost RANTES levels and thus CXCR4 use, potentially explaining the fast progression. We propose that CRF19 is evolutionary very fit and causing rapid progression to AIDS in many newly infected patients in Cuba.

  13. Developing E-Governance in the Eurasian Economic Union: Progress, Challenges and Prospects

    Directory of Open Access Journals (Sweden)

    Lyudmila Vidiasova

    2017-03-01

    Full Text Available he article provides an overview of e-governance development in the members of the Eurasian Economic Union (EEU. There is a lack of integrated research on e-governance in the EEU countries, although given the strengthening of this regional bloc, new information and communication technologies (ICT could serve as significant growth driver. Given the history and specifics of regional cooperation in the post-Soviet space and international best practices in ICT use in regional blocs, this article reviews the development of e-governance in the EEU members The research methodology was based on a three-stage concept of regionalism [Van Langenhov, Coste, 2005]. The study examines three key components: progress in developing e-governance, barriers to that development and future prospects. It used qualitative and quantitative methods. Data sources included the results of the United Nations E-Government rating, EEU countries’ regulations based on 3,200 documents and the authors’ expert survey, in which 18 experts (12 EEU representatives and six international experts participated. The study revealed the progress made by EEU countries in improving technological development and reducing human capital development indicators. The survey identified key barriers to e-governance development in the EEU: low motivation and information technology skills among civil servants, and citizens’ low computer literacy. The analysis of EEU members’ national economic priorities revealed a common focus on ICT development. The authors concluded that prospects for e-governance in the EEU were associated with strengthening regional cooperation in standardizing information systems, implementing one-stop-shop services, managing electronic documents and expanding online services. The authors presented two areas for developing e-governance within the EEU. The first is external integration, which, if strengthened, would affect the economy positivelyand optimize business processes

  14. Rapid progression of mediastinal tumor within a few days: A case report of T cell lymphoblastic lymphoma

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Tae Ran; Lee, Young Kyung; Jun, Hyun Jung; Jung, Eun Ah; Son, Jin Sung [Seoul Medical Center, Seoul (Korea, Republic of)

    2016-05-15

    T-cell lymphoblastic lymphoma is a highly aggressive tumor derived from lymphocyte of the thymus, which accounts for 2% of non-Hodgkin's lymphoma. The disease occurs most commonly in adolescent and young adult males. It often results in respiratory emergency because of high proliferation rate. In this case, we confirmed the rapid progression of T-cell lymphoblastic lymphoma through the chest CT scan with one week interval. Three days of empirical chemotherapy resulted in substantial reduction of mediastinal mass, pleural thickening and pleural effusion.

  15. Poverty and progress: choices for the developing world.

    Science.gov (United States)

    Chenery, H B

    1980-06-01

    Some development strategists equate progress with economic growth and others consider increased equity in income distribution or a reduction in poverty as indicators of progress. This report examined the empirical relationship between economic growth and income distribution using data derived from a number of recent comparative studies. Various studies supported the Kuznets hypothesis, which states that during the early phases of development income distribution worsens and improves during the later phases. These studies demonstrated that as per capita income increases in poor countries, income distribution worsens until the per capita income reaches the $800 level. After that level is reached, income distribution generally improves. In a study of 11 countries, the relationship, in recent years, between income growth for the rich and for the poor, and income growth for the country as a whole was examined. Of the 11 countries, Taiwan, Yugoslavia, Sri Lanka, Korea, and Costa Rica were ranked as good performers, since more than 30% of the increment in national income was allocated to the poorest 60% of the population. The countries of India, Philippines, Turkey, and Colombia were ranked as intermediate performers since 20-30% of the increment in national income went to the poorest 60%. Poor performance countries were Brazil, Mexico, and Peru. In these countries less than 20% of the income increment was allocated to the poorest 60%. A table provided comparative national income and income distribution data for the 11 countries. These findings did not permit an assessment of different development strategies; however, they did indicate that: 1) some countries, such as Taiwan, Yugoslavia, and Korea, achieved both rapid growth and greater income distribution equity; and that 2) although some countires, such as Sri Lanka, which stressed equity, grew less rapidly than other countries, such as Mexico, which stressed economic growth, the poor fared much better in the former

  16. A rapid and economic in-house DNA purification method using glass syringe filters.

    Directory of Open Access Journals (Sweden)

    Yun-Cheol Kim

    Full Text Available BACKGROUND: Purity, yield, speed and cost are important considerations in plasmid purification, but it is difficult to achieve all of these at the same time. Currently, there are many protocols and kits for DNA purification, however none maximize all four considerations. METHODOLOGY/PRINCIPAL FINDINGS: We now describe a fast, efficient and economic in-house protocol for plasmid preparation using glass syringe filters. Plasmid yield and quality as determined by enzyme digestion and transfection efficiency were equivalent to the expensive commercial kits. Importantly, the time required for purification was much less than that required using a commercial kit. CONCLUSIONS/SIGNIFICANCE: This method provides DNA yield and quality similar to that obtained with commercial kits, but is more rapid and less costly.

  17. Technical and economic feasibility of membrane technology. Fourth technical progress report, June 17-September 16, 1980

    Energy Technology Data Exchange (ETDEWEB)

    Sandre, A.

    1980-10-01

    Progress is reported on the investigation of the potential application of reverse osmosis, ultrafiltration and electrodialysis to the system of solids concentration in beet sugar process streams. During this period, emphasis was put on running reverse osmosis tests with a new prototype machine to select the most suitable membranes for the concentrating of sugar solutions. An economic analysis of using reverse osmosis in a factory producing 10/sup 6/ gal/day of thin juice is discussed. (DMC)

  18. FUNDAMENTAL ASPECTS OF THE ENTREPRENEURSHIP IN THE CONTEMPORARY ECONOMIC WORLD

    Directory of Open Access Journals (Sweden)

    DOBRIN IONEL GABRIEL

    2014-08-01

    Full Text Available Many individuals in the modern society are considering running their own business as the best option that they have regarding their employment. The progress of small and medium enterprises sector provides huge potential on the absorption capacity of the young labour force.Frequent and rapid changes in the structure of the work program eliminate the idea that an individual has only one job during the entire life. Therefore, people endowed with entrepreneurial skills they have to successfully cope with a new socio-economic context

  19. [Rapidly progressive compromise of cranial pairs as neurosyphilis manifestation].

    Science.gov (United States)

    Baccaro, Fernando; Moldes, Sofía; Novelli Poisson, Paola; Arduin, Julieta; Valerga, Mario

    2012-01-01

    Syphilis remains a common disease throughout the world, being neurosyphilis a relatively common manifestation. A case of a 34 years old male with HIV and neurosyphilis is presented, characterized by a clinical course evidenced by progressive palsy of cranial nerves. This case is unusual and a rare presentation of progressive cranial involvement with swallowing deficit, have found no similar data in the literature.

  20. Immunological Basis for Rapid Progression of Diabetes in Older NOD Mouse Recipients Post BM-HSC Transplantation.

    Directory of Open Access Journals (Sweden)

    Nan Wang

    Full Text Available Type I diabetes (T1D, mediated by autoreactive T cell destruction of insulin-producing islet beta cells, has been treated with bone marrow-derived hematopoietic stem cell (BM-HSC transplantation. Older non-obese diabetic (NOD mice recipients (3m, at disease-onset stage receiving syngeneic BM-HSC progressed more rapidly to end-stage diabetes post-transplantation than younger recipients (4-6w, at disease-initiation stage. FACS analyses showed a higher percentage and absolute number of regulatory T cells (Treg and lower proportion of proliferating T conventional cells (Tcon in pancreatic lymph nodes from the resistant mice among the younger recipients compared to the rapid progressors among the older recipients. Treg distribution in spleen, mesenteric lymph nodes (MLN, blood and thymus between the two groups was similar. However, the percentage of thymic Tcon and the proliferation of Tcon in MLN and blood were lower in the young resistants. These results suggest recipient age and associated disease stage as a variable to consider in BM-HSC transplantation for treating T1D.

  1. [Sustainable development of the three economic patterns in China: The application of genuine progress indicator in the sustainability assessment of six typical cities.

    Science.gov (United States)

    Li, Jing; Huang, Lu; Yan, Li Jiao

    2016-06-01

    Three economic patterns, i.e., Zhujiang Model, Wenzhou Model and Sunan Model, were all generated in the developed areas of China. Sustainability assessment of those areas plays an important role in guiding future development of the economy of China. Genuine progress indicator (GPI) was adopted in this study to evaluate the sustainability of 6 typical cities (Guangzhou, Shenzhen, Wenzhou, Suzhou, Wuxi, and Changzhou) of the three economic patterns from 1995 to 2012. During the study period, the values of GDP for the six cities had experienced exponential growth, while the values of GPI started to increase since 2005 after a relatively constant period between 1995 and 2005. The gap between GPI and GDP had been widening from a historical perspective. Zhujiang Model made great progress in economic growth, however, the economic, social, and environmental costs were evident. It should tackle income inequality, traffic jam, and environmental pollution to reach sustainability. The development of Wenzhou Model slowed down in the late pe-riod, with inadequate potential to develop. Its income inequality was tough, social and economic development was slow, and the economic development pattern needed to be urgently changed. Sunan Model had a higher value of GPI and the potential to reach sustainability, with remarkable growth of economy, median level of the GPI costs, and steady improvement of social development, although its natural resources were depleted. Three economic patterns should focus on the three dimensions of sustainability (economy, environment, and society), and Zhujiang Model and Wenzhou Model needed to be more active to search for transition of their development.

  2. Economic analysis model for total energy and economic systems

    International Nuclear Information System (INIS)

    Shoji, Katsuhiko; Yasukawa, Shigeru; Sato, Osamu

    1980-09-01

    This report describes framing an economic analysis model developed as a tool of total energy systems. To prospect and analyze future energy systems, it is important to analyze the relation between energy system and economic structure. We prepared an economic analysis model which was suited for this purpose. Our model marks that we can analyze in more detail energy related matters than other economic ones, and can forecast long-term economic progress rather than short-term economic fluctuation. From view point of economics, our model is longterm multi-sectoral economic analysis model of open Leontief type. Our model gave us appropriate results for fitting test and forecasting estimation. (author)

  3. The Current Status and Prospects of the Economic Relationship between North Korea and China

    Directory of Open Access Journals (Sweden)

    Myoungchul Cho

    1998-06-01

    Full Text Available After the socialist market collapse after 1990s, the economic relationship of North Korea and China is becoming closer. It can be proven by the fact that economic relationship between this two countries are transferring from the national trade model to various models such as border trade, agency trade, the illicit trade and investment aid. In this progress, North Korea rely China more than in 1990. But after 1992, the economic relationship is falling from the political priority as before, blind support and assistance based on the nature of the economic benefits to the rapid changes in relationship. This thesis reviewed economic relations in the world environment which has changed. First it analyzed the national economy and trade policies adopted in the current situation of two countries, and on this basis, it looked forward to the economic relationship between the two countries, and point out the measures regarding the relationship between two countries.

  4. Successful recovery of infective endocarditis-induced rapidly progressive glomerulonephritis by steroid therapy combined with antibiotics: a case report

    Directory of Open Access Journals (Sweden)

    Kikkawa Ryuichi

    2004-12-01

    Full Text Available Abstract Background The mortality rate among patients with infective endocarditis, especially associated with the presence of complications or coexisting conditions such as renal failure and the use of combined medical and surgical therapy remains still high. Prolonged parenteral administration of a bactericidal antimicrobial agent or combination of agents is usually recommended, however, the optimal therapy for infective endocarditis associated with renal injury is not adequately defined. Case presentation Patient was a 24-years old man who presented to our hospital with fever, fatigue, and rapidly progressive glomerulonephritis. He had a history of ventricular septum defect (VSD. A renal biopsy specimen revealed crescentic glomerulonephritis and echocardiogram revealed VSD with vegetation on the tricuspid valve. Specimens of blood demonstrated Propionibacterium Acnes. The intensive antibiotic therapy with penicillin G was started without clinical improvement of renal function or resolution of fever over the next 7 days. After the short-term treatment of low dose of corticosteroid combined with continuous antibiotics, high fever and renal insufficiency were dramatically improved. Conclusion Although renal function in our case worsened despite therapy with antibiotics, a short-term and low dose of corticosteroid therapy with antibiotics was able to recover renal function and the patient finally underwent tricuspid valve-plasty and VSD closure. We suggest that the patients with rapidly progressive glomerulonephritis associated with infective endocarditis might be treated with a short-term and low dose of corticosteroid successfully.

  5. On Rural Financial and Accounting Work under the Background of Rapid Agricultural Economic Development

    Institute of Scientific and Technical Information of China (English)

    Yaozheng; TANG

    2013-01-01

    Under the background of rapid agricultural economic development,rural financial and accounting work is of great significance. From rural accounting management system,rural accountant allocation and rural accounting training,this paper analyzes current situations of rural accounting work in China. In rural financial and accounting work,there are following problems. ( 1) Accounting behavior is not standard,and basic accounting work is to be further strengthened; ( 2) Internal control is not perfect and implementation of supervision mechanism is formalized; ( 3) Few people manipulate accounting behavior and accounting information is not transparent. In view of these problems,it puts forward countermeasures for improving rural accounting work: ( 1) establishing perfect agricultural accounting system; ( 2) regulating fund management order; ( 3) promoting computerized agricultural financial and accounting work; ( 4) improving professional and comprehensive quality of rural accountants.

  6. Industry and agriculture: Elements of the economic profile of Kladovo municipality

    Directory of Open Access Journals (Sweden)

    Miletić Radmila

    2006-01-01

    Full Text Available On the basis of spatial differentiation of the natural and socio-economic factors of development, we have seen the structural characteristics of the local industry and local agriculture, as two elements of the economy of Kladovo municipality, and the importance and role of these two elements in the spatial structure of the municipality. Particular attention was devoted in the course of this research, to the possibilities of intensifying the development of the less developed parts of the area. Activation of developmental potentials is directed towards a demographic revitalization and towards the establishment of a stable and progressive social-economic-ecological area, with an identity recognizable in the region. In that sense, we examine the inter-dependence of potentials limitations and risks for a more rapid future development of the municipality of Kladovo.

  7. Measuring economic performance, social progress and sustainability using an index

    International Nuclear Information System (INIS)

    de Carvalho, Joaquim Francisco

    2011-01-01

    The energy crisis and a greater awareness among the general public regarding the issue of climate change have, between them, led to a notable increase in the interest shown by governments in relation to the problem of environmental sustainability. An example has been the initiative taken by the President of France to set up a commission, known as the Sarkozy Commission, named after the President, bringing together renowned economists to study and propose forms of economic performance measurement related to social progress. This article aims to propose a methodology to establish a quantitative definition of sustainability structured on the principles of minimum and maximum entropy production, and, based on this, outline a way of organizing the many sources of, and kinds of energy, we have available to us in order of the intensity of their respective environmental impacts. Based on this, we could produce an Environmental Sustainability Index, linked to existing statistical indicators of human development, and thereby arrive at a Sustainable Human Development Index, which would be positively or negatively influenced by parameters linked to environmental sustainability and quality of life. In order to ensure that this index can produce practical results, the WTO (World Trade Organization) would have to establish a scale of increments, to be applied to export tariffs on products originating in countries with different indexes. (author)

  8. [Additional qualification in health economics--a pre-condition for ENT leadership positions?].

    Science.gov (United States)

    Lehnerdt, G; Schöffski, O; Mattheis, S; Hoffmann, T K; Lang, S

    2013-11-01

    The increasing medical-technical progress as well as the dramatic demographic changes cause problems with regard to rapid enlargement of medical service offers, allocation of resources and a financing shortfall in the German public health system. The economization in the German Health System can also be perceived in ENT departments. After performing an internet search about the rapidly growing market for qualifications measures in health economics, we hence conducted an anonymous survey for ENT senior doctors and directors of the 34 German University Departments to evaluate their attitude towards, as well as their expectation of such an add-on qualification. Since the German government finalized the health care reform in the year 2000 such qualification measures rapidly developed: amongst others, 26 postgraduate, extra-occupational master programs have been inaugurated. The anonymous survey was answered by 105 ENT doctors (63 senior doctors, 27 vice professors and 15 directors). 63% out of these 105 colleagues considered such an add-on qualification to be mandatory. 41% of the colleagues were already "add-on qualified" in that field, only 10 of them by means of a study program. 71 of 105 colleagues (68%) considered the add-on qualification to be advantageous for their future personal career. With regard to the designated contents of the study program, "Staff Management" was even prioritized to "Hospital Financing" and "Cost Accounting". Aspects of management and a (health-) economical basic knowledge became an integral part of the daily routine for "first-line management doctors" also in (University) ENT-departments. © Georg Thieme Verlag KG Stuttgart · New York.

  9. Project management for economical nuclear energy

    International Nuclear Information System (INIS)

    Majerle, P.P.

    2005-01-01

    The price of electricity is significantly influenced by the cost of the initial generation asset. The cost of the initial nuclear generation asset is significantly influenced by the design and construction duration. Negative variations in the cost and duration of actual design and construction have historically impacted the early relative economics of nuclear power generation. Successful management of plant design information will mitigate the risks of the design and construction of future nuclear plants. Information management tools that can model the integrated delivery of large complex projects enable the project owners to accurately evaluate project progress, as well as the economic impact of regulatory, political, or market activities not anticipated in the project execution plan. Significant differences exist in the electrical energy markets, project delivery models, and fuel availability between continents and countries. However, each market and project delivery model is challenged by the need to produce economical electrical energy. The information management system presented in this paper provides a means to capture in a single integrated computerized database the design information developed during plant design, procurement, and construction and to allow this information to be updated and retrieved in real time by all project participants. Utilization of the information management system described herein will enable diverse project teams to rapidly and reliably input, share, and retrieve power plant information, thereby supporting project management's goal to make good on its commitment to the economic promise of tomorrow's nuclear electrical power generation by achieving cost-effective construction. (authors)

  10. [Dynamic changes of the relationships between economic growth and environmental pressure in Gansu Province: a structural decomposition analysis].

    Science.gov (United States)

    Zhang, Zi-Long; Chen, Xing-Peng; Yang, Jing; Xue, Bing; Li, Yong-Jin

    2010-02-01

    Based on the ideology of macro environmental economics, a function of environmental pressure represented by pollutant emission was built, and the relative importance of the driving factors in the dynamic changes of the relationships between economic growth and environmental pressure in Gansu Province in 1990 - 2005 was analyzed by using structural decomposition analysis (SDA) model combining with 'refined Laspeyres' method. In the study period, the environmental pressure in the Province was mainly caused by the emission of waste gases and solids in the process of economic growth, and showed a rapid increasing trend at the late stage of the period. Population factor had less impact on the increase of this environmental pressure, while economic growth factor had obvious impact on it. Technological progress did mitigate, but could not offset the impact of economic growth factor, and the impacts of economic growth and technological factors on the environmental pressure differed with the kinds of pollutants.

  11. Unilaterally and rapidly progressing white matter lesion and elevated cytokines in a patient with Tay-Sachs disease.

    Science.gov (United States)

    Hayase, Tomomi; Shimizu, Jun; Goto, Tamako; Nozaki, Yasuyuki; Mori, Masato; Takahashi, Naoto; Namba, Eiji; Yamagata, Takanori; Momoi, Mariko Y

    2010-03-01

    We report the case of a girl with Tay-Sachs disease who had convulsions and deteriorated rapidly after an upper respiratory infection at the age of 11 months. At the age of 16 months, her seizures became intractable and magnetic resonance imaging of the brain showed high signal intensity on T2-weighted images and marked swelling in the white matter and basal nucelei of the right hemisphere. Her seizures and right hemisphere lesion improved with glycerol and dexamethasone treatment. When dexamethasone was discontinued, her symptoms worsened and lesions later appeared in the left hemisphere. Her cerebrospinal fluid showed elevated levels of the cytokines TNF-alpha and IL-5. It is considered that inflammation contributes to disease progression in Tay-Sachs disease.

  12. Microbiological characteristics of subgingival microbiota in adult periodontitis, localized juvenile periodontitis and rapidly progressive periodontitis subjects.

    Science.gov (United States)

    Nonnenmacher, C; Mutters, R; de Jacoby, L F

    2001-04-01

    To describe the prevalence of the cultivable subgingival microbiota in periodontal diseases and to draw attention to the polymicrobial nature of periodontic infections. The study population consisted of 95 patients, 51 females and 44 males, aged 14-62 years. Twenty-nine patients exhibited adult periodontitis (AP), six localized juvenile periodontitis (LJP), and 60 rapidly progressive periodontitis (RPP). Two to four pooled bacterial samples were obtained from each patient. Samples were collected with sterile paper points from the deepest periodontal pockets. The samples were cultured under anaerobic and microaerophilic conditions using selective and non-selective media. Isolates were characterized to species level by conventional biochemical tests and by a commercial rapid test system. Prevotella intermedia and Capnocytophaga spp. were the most frequently detected microorganisms in all diagnostic groups. Porphyromonas gingivalis and Peptostreptococcus micros were found more frequently in AP and RPP patients, while Actinobacillus actinomycetemcomitans and Eikenella corrodens were associated with AP, LJP and RPP patients. The other bacterial species, including Actinomyces spp., Streptococcus spp. and Eubacterium spp., were detected at different levels in the three disease groups. The data show the complexity of the subgingival microbiota associated with different periodontal disease groups, indicating that the detection frequency and levels of recovery of some periodontal pathogens are different in teeth affected by different forms of periodontal disease.

  13. Technical progress of nuclear energy: economic and environmental prospects

    International Nuclear Information System (INIS)

    Naudet, G.

    1994-01-01

    This document deals with three different aspects of the nuclear energy: first the operating and economic performances of nuclear power plants in the world, the French nuclear competitiveness. Then, the technical and economic perspectives about reactors and fuels cycle and the advantages towards atmospheric pollution are discussed to favour a new worldwide nuclear development. (TEC). 8 refs., 4 figs., 6 tabs

  14. Progress report within the series of GRS-F progress reports on reactor safety, sponsored by the Federal Ministry of Economics and Technology. Period: 1 January - 30 June, 2002

    International Nuclear Information System (INIS)

    2002-01-01

    Within its competence for energy research, the Bundesministerium fuer Wirtschaft und Technologie (BMWi) (Federal Ministry of Economics and Technology) sponsors investigations into the safety of nuclear power plants. The objective of these investigations is to provide fundamental knowledge, procedures and methods to contribute to realistic safety assessments of nuclear installations, to the further development of safety technology and to make use of the potential of innovative safety-related approaches. The Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, by order to the BMWi, continuously issues information on the status of such investigations by publishing semi-annual and annual progress reports within the series of GRS-F-Fortschrittsberichte (GRS-F-Progress Reports). Each progress report represents a compilation of individual reports about the objectives, work performed, results achieved, next steps of the work etc. The individual reports are prepared in a standard form by the research organisations themselves as documentation of their progress in work and are published by the Research Managment Division of GRS within the framework of general information on the progress in reactor safety research. The compilation of the reports is classified according to general topics related to reactor safety research. Further, use is made of the classification system 'Joint Safety Research Index' of the CEC (Commission of the European Communities). The reports are arranged in sequence of their project numbers. It has to be pointed out that the authors of the reports are responsible for the contents of this compilation. The BMWi does not take any responsibility for the correctness, exactness and completeness of the information nor for the observance of private claims of third parties. (orig.) [de

  15. Progress report within the series of GRS-F progress reports on reactor safety, sponsored by the Federal Ministry of Economics and Technology. Period: 1 July - 31 December 2001

    International Nuclear Information System (INIS)

    2002-01-01

    Within its competence for energy research, the Bundesministerium fuer Wirtschaft und Technologie (BMWi) (Federal Ministry of Economics and Technology) sponsors investigations into the safety of nuclear power plants. The objective of these investigations is to provide fundamental knowledge, procedures and methods to contribute to realistic safety assessments of nuclear installations, to the further development of safety technology and to make use of the potential of innovative safety-related approaches. The Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, by order to the BMWi, continuously issues information on the status of such investigations by publishing semi-annual and annual progress reports within the series of GRS-F-Fortschrittsberichte (GRS-F-Progress Reports). Each progress report represents a compilation of individual reports about the objectives, work performed, results achieved, next steps of the work etc. The individual reports are prepared in a standard form by the research organisations themselves as documentation of their progress in work and are published by the Research Managment Division of GRS within the framework of general information on the progress in reactor safety research. The compilation of the reports is classified according to general topics related to reactor safety research. Further, use is made of the classification system 'Joint Safety Research Index' of the CEC (Commission of the European Communities). The reports are arranged in sequence of their project numbers. It has to be pointed out that the authors of the reports are responsible for the contents of this compilation. The BMWi does not take any responsibility for the correctness, exactness and completeness of the information nor for the observance of private claims of third parties. (orig.) [de

  16. THE IMPORTANCE OF LAW AND ECONOMICS IN THE CONTEMPORARY ECONOMIC REALITY

    OpenAIRE

    Pomaskow, Joanna

    2015-01-01

    The law and economics movement can improve the functioning of companies doing business in the contemporary, rapidly changing, reality. The tensions between the idea of efficiency and the idea of justice cause difficulties in the application of tools which are proposed by the representatives of the law and economics movement in legal solutions. Economics proposes a new, fresh look at the law, which makes it easier to assess and influence the growth of its transparency. Perspective can therefor...

  17. Case report of a 28-year-old male with the rapid progression of steroid-resistant central nervous system vasculitis diagnosed by a brain biopsy.

    Science.gov (United States)

    Takahashi, Keigo; Sato, Hideki; Hattori, Hidenori; Takao, Masaki; Takahashi, Shinichi; Suzuki, Norihiro

    2017-09-30

    A 28-year-old Japanese male without a significant past medical history presented with new-onset generalized clonic seizure and headache. A brain MRI revealed multiple enhanced lesions on both cerebral hemispheres. Laboratory exams showed no evidence of systemic inflammation or auto-immune antibodies such as ANCAs. Despite four courses of high-dose methylprednisolone pulse therapy and five treatments with plasmapheresis, his symptoms worsened and the MRI lesions progressed rapidly. During these treatments, we performed a targeted brain biopsy, that revealed histological findings consistent with a predominant angiitis of parenchymal and subdural small vessels. He was provided with diagnosis of central nervous system vasculitis (CNSV). Subsequent cyclophosphamide pulse therapy enabled a progressive successful improvement of his symptoms. While diagnostic methods for CNSV remain controversial, histological findings are thought to be more useful in obtaining a more definitive diagnosis than findings in image studies, such as MRI and angiography. We suggest that a brain biopsy should be considered during the early period of cases with suspected CNSV and rapid clinical deterioration. We also detected human herpesvirus 7 (HHV-7) using PCR technology in brain biopsy specimens, however the relationship between CNSV and HHV-7 infection is unknow.

  18. The Discipline in The Making: Appraising The Progress of Islamic Economics

    Directory of Open Access Journals (Sweden)

    Hafas Furqani

    2015-08-01

    Full Text Available Islamic economics is currently moving from a mere discourse on economics in Islamic perspective towards becoming a distinct science of Islamic economics. There is a systematic effort from Islamic economic scientific community to develop a discipline of Islamic economics marked by a complete body of knowledge, clear subject matter, methodology/methodologies to appraise theories and continuous growth and accumulation of knowledge. This could be done if the scientific community put strong effort in explicating all the necessary foundations of science and achieve consensus on certain important aspect of discipline. In this paper we attempt to historically survey the development of Islamic economics towards becoming a distinct discipline, evaluate the current practices a adopted by the Islamic economics’ scientific community in settling up problems, and outlining forward agenda in order to achieve this discipline status.

  19. The poverty of liberal economics

    OpenAIRE

    Brady, David

    2003-01-01

    Liberal economic precepts have long been a foundation for the social science of poverty and continue to profoundly influence public policy. Liberal economics contends that poverty is dependent on the harmonious progress of economic growth, free market capitalism, worker productivity, and the supply and demand of labor. This paper traces its origins from classical economics and its influence throughout contemporary social science, public policy and conventional wisdom. Next, I evaluate the lib...

  20. The economic case for low-carbon development in rapidly growing developing world cities: A case study of Palembang, Indonesia

    International Nuclear Information System (INIS)

    Colenbrander, Sarah; Gouldson, Andy; Sudmant, Andrew Heshedahl; Papargyropoulou, Effie

    2015-01-01

    Where costs or risks are higher, evidence is lacking or supporting institutions are less developed, policymakers can struggle to make the case for low-carbon investment. This is especially the case in developing world cities where decision-makers struggle to keep up with the pace and scale of change. Focusing on Palembang in Indonesia, this paper considers the economic case for proactive investment in low-carbon development. We find that a rapidly growing industrial city in a developing country can reduce emissions by 24.1% in 2025, relative to business as usual levels, with investments of USD405.6 million that would reduce energy expenditure in the city by USD436.8 million. Emissions from the regional grid could be reduced by 12.2% in 2025, relative to business as usual trends, with investments of USD2.9 billion that would generate annual savings of USD175 million. These estimates understate the savings from reduced expenditure on energy subsidies and energy infrastructure. The compelling economic case for mainstreaming climate mitigation in this developing country city suggests that the constraints on climate action can be political and institutional rather than economic. There is therefore a need for more effective energy governance to drive the transition to a low-carbon economy. - Highlights: • We evaluate the economic case for low carbon investment in a developing world city. • Cost-effective measures could reduce emissions by 24.1% relative to BAU levels. • These pay for themselves in <1 year and generate savings throughout their lifetime. • Further savings come from reduced expenditure on energy infrastructure, subsidies. • Limitations on climate action seem to be political/institutional – not economic

  1. HPLC method for rapidly following biodiesel fuel transesterification reaction progress using a core-shell column.

    Science.gov (United States)

    Allen, Samuel J; Ott, Lisa S

    2012-07-01

    There are a wide and growing variety of feedstocks for biodiesel fuel. Most commonly, these feedstocks contain triglycerides which are transesterified into the fatty acid alkyl esters (FAAEs) which comprise biodiesel fuel. While the tranesterification reaction itself is simple, monitoring the reaction progress and reaction products is not. Gas chromatography-mass spectrometry is useful for assessing the FAAE products, but does not directly address either the tri-, di-, or monoglycerides present from incomplete transesterification or the free fatty acids which may also be present. Analysis of the biodiesel reaction mixture is complicated by the solubility and physical property differences among the components of the tranesterification reaction mixture. In this contribution, we present a simple, rapid HPLC method which allows for monitoring all of the main components in a biodiesel fuel transesterification reaction, with specific emphasis on the ability to monitor the reaction as a function of time. The utilization of a relatively new, core-shell stationary phase for the HPLC column allows for efficient separation of peaks with short elution times, saving both time and solvent.

  2. Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease.

    Science.gov (United States)

    Hill, Rebecca M; Kuijper, Sanne; Lindsey, Janet C; Petrie, Kevin; Schwalbe, Ed C; Barker, Karen; Boult, Jessica K R; Williamson, Daniel; Ahmad, Zai; Hallsworth, Albert; Ryan, Sarra L; Poon, Evon; Robinson, Simon P; Ruddle, Ruth; Raynaud, Florence I; Howell, Louise; Kwok, Colin; Joshi, Abhijit; Nicholson, Sarah Leigh; Crosier, Stephen; Ellison, David W; Wharton, Stephen B; Robson, Keith; Michalski, Antony; Hargrave, Darren; Jacques, Thomas S; Pizer, Barry; Bailey, Simon; Swartling, Fredrik J; Weiss, William A; Chesler, Louis; Clifford, Steven C

    2015-01-12

    We undertook a comprehensive clinical and biological investigation of serial medulloblastoma biopsies obtained at diagnosis and relapse. Combined MYC family amplifications and P53 pathway defects commonly emerged at relapse, and all patients in this group died of rapidly progressive disease postrelapse. To study this interaction, we investigated a transgenic model of MYCN-driven medulloblastoma and found spontaneous development of Trp53 inactivating mutations. Abrogation of p53 function in this model produced aggressive tumors that mimicked characteristics of relapsed human tumors with combined P53-MYC dysfunction. Restoration of p53 activity and genetic and therapeutic suppression of MYCN all reduced tumor growth and prolonged survival. Our findings identify P53-MYC interactions at medulloblastoma relapse as biomarkers of clinically aggressive disease that may be targeted therapeutically. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  3. Black economic empowerment progress in the advertising industry ...

    African Journals Online (AJOL)

    in the early 2000s to investigate allegations of racism and poor transformation progress. The Association for Communication and. Advertising (ACA) has been the main driving force of transformation within the South African advertising industry, but there have been few studies that have effectively investigated transformation ...

  4. Economism

    Directory of Open Access Journals (Sweden)

    P. Simons

    2010-07-01

    Full Text Available Modern society is characterised not only by a fascination with scientific technology as a means of solving all problems, especially those that stand in the way of material progress (technicism, but also by an obsessive interest in everything that has to do with money (economism or mammonism. The article discusses the relationship between technicism and economism, on the basis of their relationship to utilitarian thinking: the quest for the greatest happiness for the greatest number of people. Recent major studies of neo-liberalism (seen as an intensification of utilitarianism by Laval and Dardot are used as reference to the development of utilitarianism. It is suggested that the western view of the world, as expressed in economism and technicism, with a utilitarian ethics, features three absolutisations: those of theoretical thinking, technology and economics. In a second part, the article draws on the framework of reformational philosophy to suggest an approach that, in principle, is not marred by such absolutisations.

  5. The Role of Regional Economic Communities in Africa's Economic ...

    African Journals Online (AJOL)

    Despite pessimistic scholarly assessments of African REC performance, their shared objectives should facilitate the task of creating a continental economic community. Actually, African RECs show noteworthy progress in some areas but they remain hampered by constraints such as overlapping memberships, weak policy ...

  6. China's Economic Conditions

    National Research Council Canada - National Science Library

    Morrison, Wayne M

    2007-01-01

    .... China is expected to continue to enjoy rapid economic growth over the next several years, provided that it continues to implement needed reforms, particularly in regard to its inefficient state-owned...

  7. Czech Republic: A rapid transformation of fertility and family behaviour after the collapse of state socialism

    Directory of Open Access Journals (Sweden)

    Vladimíra Kantorová

    2008-07-01

    Full Text Available Following the swift demise of the state-socialist regime in 1989, a profound transformation of family and fertility patterns has taken place in the Czech Republic. Family formation has been postponed and period fertility rates have fallen to very low levels, especially among young adults. Unmarried cohabitation has become relatively widespread and marriages have been progressively delayed or even foregone. These rapid shifts in family-related behaviour were primarily driven by a period change and resulted in a sharp discontinuity in cohort patterns of union formation and childbearing. We argue that the rapid change in family-related behaviour after 1990 was driven by a fundamental shift in the constraints and incentives for childbearing, which was conducive to later and more carefully planned family formation. The rapidity of observed changes can be explained as the outcome of a simultaneous occurrence of several factors, especially the expansion of higher education, the emergence of new opportunities competing with family life, increasing job competition, rising economic uncertainty in young adulthood, and changing partnership behaviour.

  8. Risk-taking under progressive taxation

    OpenAIRE

    Bamberg, Günter

    1988-01-01

    Risk-taking under progressive taxation : 3 partial effects / Günter Bamberg ; Wolfram R. Richter. - In: Measurement in economics / ed. by Wolfgang Eichhorn. - Heidelberg : Physica-Verl., 1988. - S. 479-497

  9. Economics of nuclear and renewables

    International Nuclear Information System (INIS)

    Khatib, Hisham; Difiglio, Carmine

    2016-01-01

    This paper provides an assessment of the economic challenges faced by both nuclear power and “new” renewable electricity technologies. The assessment reflects the need to incorporate new renewables into power grids and issues faced in dispatching power and their effect on traditional electricity technologies as well as the need for transmission extension and/or grid reinforcement. Wider introduction of smart grids and the likely demise of nuclear in some OECD countries are bound to enhance the future prospects for new renewables. However, their immediate future expansion will depend on continued subsidies, which are becoming difficult to sustain in present economic circumstances. Development of large energy storage facilities and carbon pricing could significantly enhance future renewable energy prospects. Correspondingly, expanding renewable energy, in spite of their popularity with some governments and sections of the public, is likely to face challenges which will slow their present rapid progress. Nuclear is now shied away from in many industrialized countries and having mixed prospects in developing economies. In many instances, it suffers from high initial costs, long lead times and often excessive construction delays. Nuclear power also faces challenging risks – investment as well as regulatory. In contrast to renewables, its share of global energy consumption is declining. - Highlights: •Renewables are increasing their energy share. •Renewables system cost is higher than their production cost. •Nuclear share is not increasing and their costs are not reduced. •Discount rate and subsidies are important in economics of renewables and nuclear.

  10. Factors of progress in reading literacy test

    Directory of Open Access Journals (Sweden)

    Jovanović Vitomir

    2011-01-01

    Full Text Available The main goal of this study was to identify the factors which are most associated with the progress in reading literacy assessed in the PISA survey. In the preliminary sample, students from ten schools (N=235 were retested two years after the 2009 PISA original study. There were measured intrinsic and extrinsic motivation, school self-efficacy, epistemological beliefs, metacognitive strategies, socio-economic status, enjoyment and preference for reading and motivation and self-regulation. The examined factors explain 27% of the variance in reading literacy progress. Factors that contribute most to this progress are school self-efficacy, proper use of metacognitive strategies and low extrinsic motivation. Socio-economic status explained a negligible amount of variance, while some effect of type of school on progress in reading literacy (η2=7% was observed. Achievement in reading literacy is correlated with school marks. Students who attend secondary schools are more likely to make progress in reading literacy than those who attend vocational schools. An attempt was made to formulate the implications for education policy based on this research.

  11. Primate amygdala neurons evaluate the progress of self-defined economic choice sequences.

    Science.gov (United States)

    Grabenhorst, Fabian; Hernadi, Istvan; Schultz, Wolfram

    2016-10-12

    The amygdala is a prime valuation structure yet its functions in advanced behaviors are poorly understood. We tested whether individual amygdala neurons encode a critical requirement for goal-directed behavior: the evaluation of progress during sequential choices. As monkeys progressed through choice sequences toward rewards, amygdala neurons showed phasic, gradually increasing responses over successive choice steps. These responses occurred in the absence of external progress cues or motor preplanning. They were often specific to self-defined sequences, typically disappearing during instructed control sequences with similar reward expectation. Their build-up rate reflected prospectively the forthcoming choice sequence, suggesting adaptation to an internal plan. Population decoding demonstrated a high-accuracy progress code. These findings indicate that amygdala neurons evaluate the progress of planned, self-defined behavioral sequences. Such progress signals seem essential for aligning stepwise choices with internal plans. Their presence in amygdala neurons may inform understanding of human conditions with amygdala dysfunction and deregulated reward pursuit.

  12. So Young and Already Victims of Stereotype Threat: Socio-Economic Status and Performance of 6 to 9 Years Old Children on Raven's Progressive Matrices

    Science.gov (United States)

    Desert, Michel; Preaux, Marie; Jund, Robin

    2009-01-01

    The aim of this study was to verify whether children from low socio-economic status (SES) are victims of stereotype threat. Children in first grade (6 to 7 years old) and third grade (8 to 9 years old) performed Raven's progressive matrices, an intellectual ability test commonly used by psychologists. The test was presented either with the…

  13. The economic impact of multiple sclerosis to the patients and their families in Norway.

    Science.gov (United States)

    Svendsen, B; Grytten, N; Bø, L; Aarseth, H; Smedal, T; Myhr, K-M

    2018-04-21

    Multiple sclerosis (MS) imposes high economic costs on society, but the patients and their families have to bear some of these costs. We aimed to estimate the magnitude of these economic costs in Norway. We collected data through a postal questionnaire survey targeting 922 MS patients in Hordaland County, western Norway, in 2013-2014; 546 agreed to participate and were included. The questionnaire included clinical and demographic characteristics, volume and cost of MS-related resource use, work participation, income, government financial support, and disability status. The mean annual total economic costs for the patients and their families were €11,603. Indirect costs accounted for 66% and were lower for women than for men. The direct costs were nearly identical for men and women. The costs increased up to Expanded Disability Status Scale score 6 except for steps between 3 and 4 where it remained nearly constant. The costs reduced from EDSS 6 to 8, and increased from 8 to 9. Lifetime costs ranged from €24,897 to €70,021 for patients with late disease onset and slow progression, and between €441,934 and €574,860 for patients with early onset and rapid progression. The economic costs of MS impose a heavy burden on the patients and their families. Supplementing the information on the cost of MS to society, our finding should be included as background information in decisions on reimbursing and allocating public resources for the well-being of MS patients and their families.

  14. [Ecological risk assessment of human activity of rapid economic development regions in southern Jiangsu, China: a case study of Dantu District of Zhenjiang City].

    Science.gov (United States)

    Fang, Guang-Ling; Xiang, Bao; Wang, Bao-Liang; Jin, Xia; Hu, Yu; Zhang, Li-Kun

    2014-04-01

    This article investigated the spatiotemporal variation of landscape ecological risk in Dantu District of Zhenjiang City with statistical method based on the ETM remote sensing data in 2000 and 2005, and the TM remote sensing data in 2010, and quantitative index of regional ecological risk assessment was established with the employment of landscape index, so as to enhance the ecosystem management, prevent and reduce the regional ecological risk in southern Jiangsu with rapid economic development. The results showed that the fragmentations, divergence, and ecological losses of natural landscape types, such as forestland, wetland, waters, etc., were deteriorated with the expansion of built-up lands from 2000 to 2010. The higher ecological risk zone took up 5.7%, 9.0%, and 10.2% of the whole region in 2000, 2005, and 2010, respectively, which mainly distributed in the plain hilly region. During the study period, the area aggravating to the higher ecological risk zone was approximately 296.2 km2, 48% of the whole region. The ecological risk rose up in most of the region. The interference of rapid economic development to landscape patterns was even more intensive, with obvious spatial differences in ecological risk distribution. The measures of exploiting resources near the port, utilizing natural wetlands, constructing industrial parks, and rapid urbanization, etc., intensified the ecological risk and accelerated the conversion rate. Prompt strategies should be established to manage the ecological risk of this region.

  15. Rapidly destructive osteoarthritis of the hip joint: a case series

    Directory of Open Access Journals (Sweden)

    McMurtrie A

    2008-01-01

    Full Text Available Abstract Background Rapidly destructive arthrosis of the hip is a rare and incompletely understood disorder with scarce literature about variations in natural history within a population. Methods A series of cases from North Wales with rapid progressive joint destruction and extensive subchondral bone loss in the femoral head and acetabulum are presented. Radiographic findings mimicked those of other disorders such as septic arthritis, rheumatoid and seronegative arthritis, primary osteonecrosis with secondary osteoarthritis, or neuropathic osteoarthropathy, but none of the patients had clinical, pathologic, or laboratory evidence of these entities. Results Rapid progression of hip pain and disability was a consistent clinical feature. The average duration of symptoms was 1.4 years. Radiographs obtained at various intervals before surgery (average 14 months in 18 patients documented rapid hip destruction, involvement being unilateral in 13 cases. All patients underwent total hip arthroplasty, and osteoarthritis was confirmed at pathologic examination. Conclusion The authors postulate that these cases represent an uncommon subset of osteoarthritis and regular review, both clinically and radiologically, are required to assess speed of progression and prevent rapid loss of bone stock without the surgeon being aware. These cases are unsuitable for being placed on long waiting list due to technical difficulties in delayed surgery and compromised outcome following surgery.

  16. Rapid Disease Progression With Delay in Treatment of Non-Small-Cell Lung Cancer

    International Nuclear Information System (INIS)

    Mohammed, Nasiruddin; Kestin, Larry Llyn; Grills, Inga Siiner; Battu, Madhu; Fitch, Dwight Lamar; Wong, Ching-yee Oliver; Margolis, Jeffrey Harold; Chmielewski, Gary William; Welsh, Robert James

    2011-01-01

    Purpose: To assess rate of disease progression from diagnosis to initiation of treatment for Stage I-IIIB non-small-cell lung cancer (NSCLC). Methods and Materials: Forty patients with NSCLC underwent at least two sets of computed tomography (CT) and 18-fluorodeoxyglucose positron emission tomography (PET) scans at various time intervals before treatment. Progression was defined as development of any new lymph node involvement, site of disease, or stage change. Results: Median time interval between first and second CT scans was 13.4 weeks, and between first and second PET scans was 9.0 weeks. Median initial primary maximum tumor dimension (MTD) was 3.5 cm (0.6-8.5 cm) with a median standardized uptake value (SUV) of 13.0 (1.7-38.5). The median MTD increased by a median of 1.0 cm (mean, 1.6 cm) between scans for a median relative MTD increase of 35% (mean, 59%). Nineteen patients (48%) progressed between scans. Rate of any progression was 13%, 31%, and 46% at 4, 8, and 16 weeks, respectively. Upstaging occurred in 3%, 13%, and 21% at these intervals. Distant metastasis became evident in 3%, 13%, and 13% after 4, 8, and 16 weeks, respectively. T and N stage were associated with progression, whereas histology, grade, sex, age, and maximum SUV were not. At 3 years, overall survival for Stage III patients with vs. without progression was 18% vs. 67%, p = 0.05. Conclusions: With NSCLC, treatment delay can lead to disease progression. Diagnosis, staging, and treatment initiation should be expedited. After 4-8 weeks of delay, complete restaging should be strongly considered.

  17. Addressing global health, economic, and environmental problems through family planning.

    Science.gov (United States)

    Speidel, J Joseph; Grossman, Richard A

    2011-06-01

    Although obstetrician-gynecologists recognize the importance of managing fertility for the reproductive health of individuals, many are not aware of the vital effect they can have on some of the world's most pressing issues. Unintended pregnancy is a key contributor to the rapid population growth that in turn impairs social welfare, hinders economic progress, and exacerbates environmental degradation. An estimated 215 million women in developing countries wish to limit their fertility but do not have access to effective contraception. In the United States, half of all pregnancies are unplanned. Voluntary prevention of unplanned pregnancies is a cost-effective, humane way to limit population growth, slow environmental degradation, and yield other health and welfare benefits. Family planning should be a top priority for our specialty.

  18. Economic impacts of bus rapid transit in southeast Michigan.

    Science.gov (United States)

    2015-12-01

    In recent years, Bus Rapid Transit (BRT) has generated great interest across the United States. There are more than 20 BRT : systems in existence, and more are in the planning stage (including in Detroit). Within the next few years, BRT will be plann...

  19. Principles of Neo-Schumpeterian Economics

    OpenAIRE

    Horst Hanusch; Andreas Pyka

    2005-01-01

    Within the last 25 years large progress has been made in Neo-Schumpeterian Economics, this branch of economic literature which deals with dynamic processes causing qualitative transformation of economies basically driven by the introduction of novelties in their various and multifaceted forms. By its very nature, innovation and in particular technological innovation is the most exponent and most visible form of novelty. Therefore it is not very surprising that Neo-Schumpeterian Economics toda...

  20. Are Forecast Updates Progressive?

    NARCIS (Netherlands)

    C-L. Chang (Chia-Lin); Ph.H.B.F. Franses (Philip Hans); M.J. McAleer (Michael)

    2010-01-01

    textabstractMacro-economic forecasts typically involve both a model component, which is replicable, as well as intuition, which is non-replicable. Intuition is expert knowledge possessed by a forecaster. If forecast updates are progressive, forecast updates should become more accurate, on average,

  1. The natural history of primary progressive multiple sclerosis

    NARCIS (Netherlands)

    Koch, Marcus; Kingwell, Elaine; Rieckmann, Peter; Tremlett, Helen

    2009-01-01

    Background: Primary progressive multiple sclerosis (PPMS) carries the worst prognosis of the multiple sclerosis (MS) subtypes and is currently untreatable. A previous analysis of the British Columbia MS database challenged the view that disability progression is rapid in PPMS, but identified few

  2. Progressive technologies in furniture design

    OpenAIRE

    Šebková, Martina

    2014-01-01

    Šebková, M. Progressive technologies in furniture design. Diploma thesis, Brno, Mendel University in Brno, 2014 Diploma thesis 'Progressive technologies in furniture design' is focused on the use of modern technologies in furniture production. The theoretical part explains the basic terms, technology and material options. It focuses mainly on the production of 3D printed furniture and possibilities of virtual testing, measurements, scanning and rapid prototyping. Practical part of diploma the...

  3. Assessment of a progressive electricity tax

    International Nuclear Information System (INIS)

    2000-01-01

    Progressive electricity tax implies that the tax rate increases with consumption so that the tax paid per kWh consumed increases when the consumption increases beyond a certain level. This elucidation discusses principal and practical aspects of such a tax. It is advised against the establishment of a progressive electricity tax. The objections are of principal, economical and administrative character

  4. MODELLING OF TOURISM SERVICE DYNAMICS UNDER THE INFLUENCE OF ECONOMIC PATTERN OF SOCIETY

    Directory of Open Access Journals (Sweden)

    Lesya Buyak

    2016-11-01

    Full Text Available Tourism as a phenomenon of social life is a derivative of social development. Its appearance is attributed to the industrial stage of human development, which was inherent in the accelerated development of the productive forces, deepening division of labour, development of urbanization processes. Accelerated innovation changes related to scientific and technological progress contributed to the overall socio-economic development of certain countries, improve the living standards of their populations, changed the nature of work, method and way of life, especially evident in the XX century. Urbanization and changes in the settlement system, post-industrial phase of economic development, deepening comprehension of environmental issues and global dimension of humanity, humanization of all spheres of public life. The increase in tourist flows in all regions complicates the management of enterprises, schemes of partnership in the process in tourism, which, among other things, is accompanied by rising levels of consumer education, and therefore their quality requirements for end tourism product, the rapid increase in supply, there is a need to study the characteristics of consumer behaviour, search for existing reserves to build capacity of individual enterprises, isolation and effective use of effective methods and tools of influence on consumer choice of consumers. Development and implementation of an effective mechanism of formation of market supply needs an assessment of consumer behaviour on quantitative and qualitative indicators. The rapid development of tourism, of course, helps determine the types and methods of calculating these indicators. These problems and targeted research are considered in this article. The subject of research is the concept and tools of analysis, mathematical modelling of the economic structure of society in dynamic tourist services. Research methodology is economic and mathematical models, algorithms and processes

  5. 10th Anniversary Focus: From mainstream 'environmental economics' to 'sustainability economics'. On the need for new thinking.

    Science.gov (United States)

    Söderbaum, Peter

    2008-12-01

    Traditional ideas of science as being separate and separable from ideology and politics have to be reconsidered. Each interpretation of sustainable development is not only scientific but at the same time ideological. For this reason our ideas about good science should also be related to normal imperatives of democracy. Mainstream neoclassical economics is specific in scientific and ideological terms. This paradigm is useful for some purposes and has played a role as a mental map in guiding us towards economic growth and other ideas about progress in society and the economy. Sustainable development, however, represents an ideological turn in our ideas about progress and it is no longer clear that neoclassical theory will be enough. Alternative perspectives in economics are being developed as part of a pluralistic strategy and the monopoly position of neoclassical economists at university departments of economics is thereby challenged. A 'political economic person' is suggested as alternative (complement) to Economic Man assumptions and a 'political economic organization' to be compared with the neoclassical profit maximizing firm. Alternative ways of understanding markets and international trade, efficiency, decision-making, monitoring and assessment are also needed. It is argued that such an alternative mental map is useful for actors who take the challenge of sustainable development seriously.

  6. Enusa's contribution to economic progress in local and regional scope

    International Nuclear Information System (INIS)

    Sanchez Macias, J. L.; Rodriguez Lopez, F.

    2010-01-01

    In this paper, we analyze the economic impact of Enusa's activity in the province of Salamanca in the last 25 years. input-output techniques were used to obtain an estimation of the total effects. The results reveal that its contribution to wealth and employment creation has been very significant, making n economic engine in its influence area. In addition to that, there are spillover effects derived rom Enusa's leadership in human resources and quality management policies. (Author)

  7. NBIC-TECHNOLOGIES GET OVER ECONOMIC DEPRESSION

    Directory of Open Access Journals (Sweden)

    A. A. Akaev

    2014-01-01

    Full Text Available This paper is reflecting results of forecasting scenario of economic growth and shown that NBIC-technologies, due to the powerful synergetic effect generating by a mutual convergence of nano-, bio-, info- and cognitive technologies, will give strong acceleration pace of technological progress, which exceeded the rate achieved in the previous upward wave of 5th great Kondratieff ’s economic cycle (1982–2006. On the base of theUSAeconomy data, the results of forecasting shows that the rate of technological progress will increase from 2,2% in 1980 to 3,5% in the 2030 s. 

  8. Relapsing and Progressive Tumefactive Demyelinating Form of Central Nervous System Involvement in a Patient with Progressive Systemic Sclerosis

    International Nuclear Information System (INIS)

    Kim, Ho Kyun; Lee, Hui Joong

    2013-01-01

    White matter hyper intensities (WMHI) on MRI are not rare in patients with progressive systemic sclerosis (PSS). In this presentation, WMHI were developed in both middle cerebellar peduncles and temporal white matter in a patient with PSS, and regressed after medication of high dose steroid. However, new lesions were developed in the subcortices of both precentral gyri, and progressed rapidly to tumefactive hyperintensity on MRI. We report an unusual relapsing and progressive tumefactive demyelinating form of central nervous system involvement in PSS.

  9. China's Economic Conditions

    National Research Council Canada - National Science Library

    Morrison, Wayne M

    2008-01-01

    ... (the fastest annual growth since 1994). While China is expected to continue to enjoy rapid economic growth in the years ahead and could become the world s largest economy within a decade or so, it faces a number of challenges, including...

  10. China's Economic Conditions

    National Research Council Canada - National Science Library

    Morrison, Wayne M

    2008-01-01

    ... (the fastest annual growth since 1994). While China is expected to continue to enjoy rapid economic growth in the years ahead and could become the world's largest economy within a decade or so, it faces a number of challenges, including...

  11. Does a Progressive PIT Stabilize the Economy? A Comparison of Progressive and Flat Taxes

    Directory of Open Access Journals (Sweden)

    Krajewski Piotr

    2017-03-01

    Full Text Available The aim of the article is to examine the impact of progressive personal income tax rates and the effectiveness of this tax as an automatic economic stabilizer. The assessment of automatic stabilizers is based on the estimates of tax cyclical components. The study shows that the output elasticity of PIT is higher than one, which means that the analysed tax acts relatively efficiently as an automatic stabilizer. However, it was also observed that the tax progressivity is not the main reason of the effectiveness of a progressive PIT as an automatic stabilizer. The study shows that changes in progressive rates of PIT, contrary to widespread opinions, have little effect on the effectiveness of passive fiscal policy. Personal income tax acts as automatic stabilizer mostly due not to the progressive tax rates, but because of the sensitivity of employment to GDP fluctuations.

  12. Towards an economics of well-being

    NARCIS (Netherlands)

    McGregor, J.A.; Pouw, N.

    2017-01-01

    There is growing concern that presently dominant frameworks in economics no longer provide a way of adequately addressing and analysing the problems of today’s globalising and rapidly changing world. This article makes a number of fundamental proposals about how we might reframe economics to move it

  13. Progress on development of nuclear power in Japan

    International Nuclear Information System (INIS)

    Anon.

    2000-01-01

    Since three Laws on the nuclear power were published 45 years has passed. Now, development on nuclear power in Japan is at an emergent state. In Japan, 51 units of commercial nuclear reactors with 44.917 GW are in operation, occupy about 37% of total electric power generation, and is positioned at an essential basic energy source supporting economical society in Japan. However, an accident occurred at Tokai Works of the JCO Co., Ltd., one of the uranium reconversion company, on September 30, 1999, was the first critical accident in Japan, and became the worst case in history on development of nuclear power in Japan, because of forming three heavy radiation disabled persons (One of them was dead) in its operators. This was a big crisis with relation to existence on development of nuclear power in Japan, by which anxiety and distrust of the Japanese against the nuclear power were amplified rapidly. On the other side, for Japan short in energy sources and of a big energy consumption, in order to intend for a long term to carry out energy security, global environmental conservation, and sustainable maintenance of essential growth, it remains to be one of important optional methods to further promote nuclear power generation and to establish nuclear fuel cycle. Here were described on progress on peaceful applications of nuclear power in Japan, progress on the field of nuclear power in Japan (from 1955 to 1999), progress on Tokai nuclear power station, introduction of nuclear power generation and effort on its domestic production. (G.K.)

  14. Rapid thermal processing of semiconductors

    CERN Document Server

    Borisenko, Victor E

    1997-01-01

    Rapid thermal processing has contributed to the development of single wafer cluster processing tools and other innovations in integrated circuit manufacturing environments Borisenko and Hesketh review theoretical and experimental progress in the field, discussing a wide range of materials, processes, and conditions They thoroughly cover the work of international investigators in the field

  15. The economics of information systems and software

    CERN Document Server

    Veryard, Richard

    2014-01-01

    The Economics of Information Systems and Software focuses on the economic aspects of information systems and software, including advertising, evaluation of information systems, and software maintenance. The book first elaborates on value and values, software business, and scientific information as an economic category. Discussions focus on information products and information services, special economic properties of information, culture and convergence, hardware and software products, materiality and consumption, technological progress, and software flexibility. The text then takes a look at a

  16. Rapidly aggravated Creutzfeldt-Jacob disease: autopsy-proven case

    Energy Technology Data Exchange (ETDEWEB)

    Park, Seung Hyun; Kang, Hyun Koo; Yu, Hyeon; Lee, Sang Chun [Seoul Veterans Hospital, Seoul (Korea, Republic of)

    2005-11-15

    Creutzfeldt-Jakob disease (DJD) is one of the transmissible spongiform encephalopathies, which is mediated by what has been known as 'prion'. It is a rare and fatal progressive neurodegenerative disease that affects the middle and old aged. There are a number of subtypes of CJD, one of which is the sporadic type characterized by rapidly progressing clinical symptoms, including progressive dementia, myoclonic jerk, and pyramidal or extrapyramidal syndrome. Patients usually end up dying within 1 to 2 years of contacting the disease. We report an autopsy-proven case of sporadic CJD with clinical symptoms that progressed within several days, along with dramatic changes on diffusion weighted magnetic resonance images.

  17. Rapidly aggravated Creutzfeldt-Jacob disease: autopsy-proven case

    International Nuclear Information System (INIS)

    Park, Seung Hyun; Kang, Hyun Koo; Yu, Hyeon; Lee, Sang Chun

    2005-01-01

    Creutzfeldt-Jakob disease (DJD) is one of the transmissible spongiform encephalopathies, which is mediated by what has been known as 'prion'. It is a rare and fatal progressive neurodegenerative disease that affects the middle and old aged. There are a number of subtypes of CJD, one of which is the sporadic type characterized by rapidly progressing clinical symptoms, including progressive dementia, myoclonic jerk, and pyramidal or extrapyramidal syndrome. Patients usually end up dying within 1 to 2 years of contacting the disease. We report an autopsy-proven case of sporadic CJD with clinical symptoms that progressed within several days, along with dramatic changes on diffusion weighted magnetic resonance images

  18. Recent progress of seismic research on tall buildings in China Mainland

    Science.gov (United States)

    Lu, Xilin; Jiang, Huanjun

    2014-08-01

    As a result of rapid economic growth and urbanization in the past two decades, many tall buildings have been constructed in China Mainland, offering researchers and practitioners an excellent opportunity for research and practice in the field of structural engineering. This paper reviews progress by researchers throughout China Mainland on the seismic research of tall buildings, focusing on three major topics that impact the seismic performance of tall buildings. These are: (1) new types of steel-concrete composite structural members such as steel-concrete composite shear walls and columns, (2) earthquake resilient shear wall structures such as shear walls with replaceable structural components, self-centering shear walls and rocking walls, and (3) performance-based seismic design, including seismic performance index, performance level and design method. The paper concludes by presenting future research needs and directions in this field.

  19. An atypical cause of rapidly progressing breast lump with abscess formation: Pure squamous cell carcinoma of the breast.

    Science.gov (United States)

    Cilekar, Murat; Erkasap, Serdar; Oner, Ulku; Akici, Murat; Ciftci, Evrim; Dizen, Hayrettin; Turel, Serkan; Kavak, Ozgu I; Yilmaz, Sezgin

    2015-01-01

    Squamous cell carcinoma (SCC) is a rare type of breast malignancy and little is known about long-term outcome. In the present report, the clinical features, histopathologic findings and postoperative course of a patient with squamous cell carcinoma are described. We have treated a 47-years-old woman who admitted for right breast mass without any discharge, bleeding and pain. The tumor was, 3 × 2 × 1.5 cm in size with central abscess formation. The result of surgical biopsy revealed large cell keratinizing type of SCC. The metastatic work-up studies ruled out any other probable sources of primary tumor. The patient was performed modified radical mastectomy and axillary dissection and received two cycles of chemotherapy. Squamous cell carcinoma of the breast (SCCB) is a rare entity and should be considered in patients with rapidly progressing breast mass. It should also be considered in breast lesions with abscess formation. The initial therapeutic approach should be surgical excision after histopathological diagnosis.

  20. Progress and challenges to the global waste management system.

    Science.gov (United States)

    Singh, Jagdeep; Laurenti, Rafael; Sinha, Rajib; Frostell, Björn

    2014-09-01

    Rapid economic growth, urbanization and increasing population have caused (materially intensive) resource consumption to increase, and consequently the release of large amounts of waste to the environment. From a global perspective, current waste and resource management lacks a holistic approach covering the whole chain of product design, raw material extraction, production, consumption, recycling and waste management. In this article, progress and different sustainability challenges facing the global waste management system are presented and discussed. The study leads to the conclusion that the current, rather isolated efforts, in different systems for waste management, waste reduction and resource management are indeed not sufficient in a long term sustainability perspective. In the future, to manage resources and wastes sustainably, waste management requires a more systems-oriented approach that addresses the root causes for the problems. A specific issue to address is the development of improved feedback information (statistics) on how waste generation is linked to consumption. © The Author(s) 2014.

  1. CORRELATION BETWEEN ECONOMIC GROWTH AND UNEMPLOYMENT

    Directory of Open Access Journals (Sweden)

    Savu Mihaela

    2013-06-01

    Full Text Available The mankind progress is built on economic growth.Yet, the high rates of economic growth must be properly used and correlated with other macroeconomic indicators in order to get the aimed effects.At the Romanian economic level, there is an inverse ratio connection between the gross domestic product and the unemployed number, a connection of low intensity.The correlation of these two indicators was established using parametric and nonparametric methods of analyzing the statistic connection using the informatic soft. Setting the recession function allows us to calculate the unemployed number depending on the forecasting of the economic growth in Romania.

  2. Promoting Women's Economic Participation in India

    OpenAIRE

    Ghani, Ejaz; Kerr, William R.; O'Connell, Stephen D.

    2013-01-01

    Despite rapid economic growth, gender disparities in women's economic participation have remained deep and persistent in India. What explains these gender disparities? Is it poor infrastructure, limited education, or the composition of the labor force and industries? Or is it deficiencies in social and business networks and a low share of incumbent female entrepreneurs? This note analyzes ...

  3. Uremic Solutes in Chronic Kidney Disease and Their Role in Progression.

    Directory of Open Access Journals (Sweden)

    Jan A J G van den Brand

    Full Text Available To date, over 150 possible uremic solutes have been listed, but their role in the progression of CKD is largely unknown. Here, the association between a selected panel of uremic solutes and progression in CKD patients was investigated.Patients from the MASTERPLAN study, a randomized controlled trial in CKD patients with a creatinine clearance between 20 and 70 ml/min per 1.73m2, were selected based on their rate of eGFR decline during the first five years of follow-up. They were categorized as rapid (decline >5 ml/min per year or slow progressors. Concentrations of eleven uremic solutes were obtained at baseline and after one year of follow-up. Logistic regression was used to compare the odds for rapid to slow progression by uremic solute concentrations at baseline. Variability in uremic solute levels was assessed using scatter plots, and limits of variability were calculated.In total, 40 rapidly and 40 slowly progressing patients were included. Uremic solutes were elevated in all patients compared to reference values for healthy persons. The serum levels of uremic solutes were not associated with rapid progression. Moreover, we observed substantial variability in solute levels over time.Elevated concentrations of uremic solutes measured in this study did not explain differences in rate of eGFR decline in CKD patients, possibly due to lack of power as a result of the small sample size, substantial between patient variability, and variability in solute concentrations over time. The etiology of intra-individual variation in uremic solute levels remains to be elucidated.

  4. Uremic Solutes in Chronic Kidney Disease and Their Role in Progression.

    Science.gov (United States)

    van den Brand, Jan A J G; Mutsaers, Henricus A M; van Zuilen, Arjan D; Blankestijn, Peter J; van den Broek, Petra H; Russel, Frans G M; Masereeuw, Rosalinde; Wetzels, Jack F M

    2016-01-01

    To date, over 150 possible uremic solutes have been listed, but their role in the progression of CKD is largely unknown. Here, the association between a selected panel of uremic solutes and progression in CKD patients was investigated. Patients from the MASTERPLAN study, a randomized controlled trial in CKD patients with a creatinine clearance between 20 and 70 ml/min per 1.73m2, were selected based on their rate of eGFR decline during the first five years of follow-up. They were categorized as rapid (decline >5 ml/min per year) or slow progressors. Concentrations of eleven uremic solutes were obtained at baseline and after one year of follow-up. Logistic regression was used to compare the odds for rapid to slow progression by uremic solute concentrations at baseline. Variability in uremic solute levels was assessed using scatter plots, and limits of variability were calculated. In total, 40 rapidly and 40 slowly progressing patients were included. Uremic solutes were elevated in all patients compared to reference values for healthy persons. The serum levels of uremic solutes were not associated with rapid progression. Moreover, we observed substantial variability in solute levels over time. Elevated concentrations of uremic solutes measured in this study did not explain differences in rate of eGFR decline in CKD patients, possibly due to lack of power as a result of the small sample size, substantial between patient variability, and variability in solute concentrations over time. The etiology of intra-individual variation in uremic solute levels remains to be elucidated.

  5. Neoclassical economic orthodoxy and the need for a new post-crisis economic paradigm

    Directory of Open Access Journals (Sweden)

    Andrei JOSAN

    2013-08-01

    Full Text Available Capitalism is a social adaptive system that evolve, change and grow in response to the challenges of a rapidly changing economic environment. When capitalism is seriously threatened by a systemic crisis, a new version much better adapted to existing conditions appears. Critical analysis of the fundamental ideas underlying neoclassical economic theory shows that the capitalist system is fundamentally a dynamic and therefore static neoclassical models proved to be unsuitable for studying it. Contrary to neoclassical economic vision, the capitalist economy is not governed by immutable economic laws. Global systemic crisis of capitalism that began in 2007 has highlighted the need for a new economic paradigm on which to be built and to be performed a new version of capitalism, in line with the increasingly complex realities of a globalized and quick changing world.

  6. Progress on high-performance rapid prototype aluminum mirrors

    Science.gov (United States)

    Woodard, Kenneth S.; Myrick, Bruce H.

    2017-05-01

    Near net shape parts can be produced using some very old processes (investment casting) and the relatively new direct metal laser sintering (DMLS) process. These processes have significant advantages for complex blank lightweighting and costs but are not inherently suited for producing high performance mirrors. The DMLS process can provide extremely complex lightweight structures but the high residual stresses left in the material results in unstable mirror figure retention. Although not to the extreme intricacy of DMLS, investment casting can also provide complex lightweight structures at considerably lower costs than DMLS and even conventional wrought mirror blanks but the less than 100% density for casting (and also DMLS) limits finishing quality. This paper will cover the progress that has been made to make both the DMLS and investment casting processes into viable near net shape blank options for high performance aluminum mirrors. Finish and figure results will be presented to show performance commensurate with existing conventional processes.

  7. Innovation, entrepreneurship and culture : the interaction between technology, progress and economic growth

    NARCIS (Netherlands)

    Brown, T.E.; Ulijn, J.M.

    2004-01-01

    Any technological advance, innovation or economic growth created by an organization is dependent on how that organization’s culture and environment fosters or inhibits these developments. This process is further complicated by the global nature of economic activity and differences in national

  8. Improving early cycle economic evaluation of diagnostic technologies

    NARCIS (Netherlands)

    Steuten, Lotte Maria Gertruda; Ramsey, Scott D.

    2014-01-01

    The rapidly increasing range and expense of new diagnostics, compels consideration of a different, more proactive approach to health economic evaluation of diagnostic technologies. Early cycle economic evaluation is a decision analytic approach to evaluate technologies in development so as to

  9. Progressive multifocal leukoencephalopathy limited to the brain stem

    Energy Technology Data Exchange (ETDEWEB)

    Kastrup, O.; Maschke, M.; Diener, H.C. [Neurologische Universitaetsklinik, University of Essen (Germany); Wanke, I. [Department of Neuroradiology, University of Essen (Germany)

    2002-03-01

    Progressive multifocal leukoencephalopathy (PML) is a subacute demyelinating slow-virus encephalitis caused by the JC polyomavirus in 2-5% of patients with AIDS. MRI typically shows multiple lesions in the cerebral hemispheres. We present a rare case of rapidly evolving and lethal PML with a severe bulbar syndrome and spastic tetraparesis in a patient with AIDS. MRI showed high-signal lesions on T2-weighted images confined to the brain stem, extending from the medulla oblongata to the midbrain. JC virus polymerase chain reaction in cerebrospinal fluid was positive, and neuropathology showed the findings of PML. This case was also notable because of the rapid progression despite improved immune status with antiretroviral therapy. (orig.)

  10. Progressive Incrementalism: U.S Foreign Economic Policy Over the Next Four Years

    Directory of Open Access Journals (Sweden)

    John M. Curtis

    2013-01-01

    Full Text Available As we look ahead following last year’s U.S. presidential and congressional elections, Canadians — and Canadian business in particular — will want to have a better sense of the economic prospects, as well as the context, of U.S. foreign economic policy over the coming half-decade or so. For, notwithstanding all the talk, debates, op-ed articles, thinktank-pieces and even books in recent years suggesting or asserting the decline of American economic power, Canada’s ever-present integration and interdependence with our southern neighbour is both a reality and now, again, an important, medium-term asset. Over the coming four years and likely beyond, and once it has completed sorting out its “fiscal cliff” matter, the U.S. is positioned to be the source of increasing economic growth. The American economy has strengths: its high productivity and innovation compared to most other countries, massive piles of private sector cash leading to all sorts of investment potential, a devalued currency, and a relatively young workforce compared to the European Union, Japan, and even Canada. Therefore, although the U.S. economy continues to face large challenges related to fiscal imbalances, there are reasons to expect increasing economic growth over the medium term.

  11. Annual report on Reactor Safety Research Projects sponsored by the Ministry of Economics and Technology of the Federal Republic of Germany. Reporting period 1999. Progress report

    International Nuclear Information System (INIS)

    2000-01-01

    Within its competence for energy research, the Bundesministerium fuer Wirtschaft und Technologie (BMWi) (Federal Ministry of Economics and Technology) sponsors investigations into the safety of nuclear power plants. The objective of these investigations is to provide fundamental knowledge, procedures and methods to contribute to realistic safety assessments of nuclear installations, to the further development of safety technology and to make use of the potential of innovative safety-related approaches. The Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, by order of the BMWi, continuously issues information on the status of such investigations by publishing semi-annual and annual progress reports within the series of GRS-F-Fortschrittsberichte (GRS-F-Progress Reports). Each progress report represents a compilation of individual reports about the objectives, work performed, results achieved, next steps of the work etc. The individual reports are prepared in a standard form by the research organisations themselves as documentation of their progress in work and are published by the Research Management Division of GRS within the framework of general information on the progress in reactor safety research. The compilation of the reports is classified according to the classification system ''Joint Safety Research Index'' of the CEC (commission of the European communities). The reports are arranged in sequence of their project numbers. (orig.)

  12. Coconut lethal yellowing diseases: a phytoplasma threat to palms of global economic and social significance

    Directory of Open Access Journals (Sweden)

    Gurr M Geoff

    2016-10-01

    Full Text Available The recent discovery of Bogia Coconut Syndrome in Papua New Guinea is the first report of a lethal yellowing disease (LYD in Oceania. Numerous outbreaks of LYDs of coconut have been recorded in the Caribbean and Africa since the late 19th century and have caused the death of millions of palms across several continents during the 20th century. Despite the severity of economic losses, it was only in the 1970s that the causes of LYDs were identified as phytoplasmas, a group of insect-transmitted bacteria associated with diseases in many other economically important crop species. Since the development of polymerase chain reaction (PCR technology, knowledge of LYDs epidemiology, ecology and vectors has grown rapidly. There is no economically viable treatment for LYDs and vector-based management is hampered by the fact that vectors have been positively identified in very few cases despite many attempted transmission trials. Some varieties and hybrids of coconut palm are known to be less susceptible to LYD but none are completely resistant. Optimal and current management of LYD is through strict quarantine, prompt detection and destruction of symptomatic palms, and replanting with less susceptible varieties or crop species. Advances in technology such as loop mediated isothermal amplification (LAMP for detection and tracking of phytoplasma DNA in plants and insects, remote sensing for identifying symptomatic palms, and the advent of clustered regularly interspaced short palindromic repeats (CRISPR-based tools for gene editing and plant breeding are likely to allow rapid progress in taxonomy as well as understanding and managing LYD phytoplasma pathosystems.

  13. Coconut Lethal Yellowing Diseases: A Phytoplasma Threat to Palms of Global Economic and Social Significance.

    Science.gov (United States)

    Gurr, Geoff M; Johnson, Anne C; Ash, Gavin J; Wilson, Bree A L; Ero, Mark M; Pilotti, Carmel A; Dewhurst, Charles F; You, Minsheng S

    2016-01-01

    The recent discovery of Bogia coconut syndrome in Papua New Guinea (PNG) is the first report of a lethal yellowing disease (LYD) in Oceania. Numerous outbreaks of LYDs of coconut have been recorded in the Caribbean and Africa since the late Nineteenth century and have caused the death of millions of palms across several continents during the Twentieth century. Despite the severity of economic losses, it was only in the 1970s that the causes of LYDs were identified as phytoplasmas, a group of insect-transmitted bacteria associated with diseases in many other economically important crop species. Since the development of polymerase chain reaction (PCR) technology, knowledge of LYDs epidemiology, ecology and vectors has grown rapidly. There is no economically viable treatment for LYDs and vector-based management is hampered by the fact that vectors have been positively identified in very few cases despite many attempted transmission trials. Some varieties and hybrids of coconut palm are known to be less susceptible to LYD but none are completely resistant. Optimal and current management of LYD is through strict quarantine, prompt detection and destruction of symptomatic palms, and replanting with less susceptible varieties or crop species. Advances in technology such as loop mediated isothermal amplification (LAMP) for detection and tracking of phytoplasma DNA in plants and insects, remote sensing for identifying symptomatic palms, and the advent of clustered regularly interspaced short palindromic repeats (CRISPR)-based tools for gene editing and plant breeding are likely to allow rapid progress in taxonomy as well as understanding and managing LYD phytoplasma pathosystems.

  14. Coconut Lethal Yellowing Diseases: A Phytoplasma Threat to Palms of Global Economic and Social Significance

    Science.gov (United States)

    Gurr, Geoff M.; Johnson, Anne C.; Ash, Gavin J.; Wilson, Bree A. L.; Ero, Mark M.; Pilotti, Carmel A.; Dewhurst, Charles F.; You, Minsheng S.

    2016-01-01

    The recent discovery of Bogia coconut syndrome in Papua New Guinea (PNG) is the first report of a lethal yellowing disease (LYD) in Oceania. Numerous outbreaks of LYDs of coconut have been recorded in the Caribbean and Africa since the late Nineteenth century and have caused the death of millions of palms across several continents during the Twentieth century. Despite the severity of economic losses, it was only in the 1970s that the causes of LYDs were identified as phytoplasmas, a group of insect-transmitted bacteria associated with diseases in many other economically important crop species. Since the development of polymerase chain reaction (PCR) technology, knowledge of LYDs epidemiology, ecology and vectors has grown rapidly. There is no economically viable treatment for LYDs and vector-based management is hampered by the fact that vectors have been positively identified in very few cases despite many attempted transmission trials. Some varieties and hybrids of coconut palm are known to be less susceptible to LYD but none are completely resistant. Optimal and current management of LYD is through strict quarantine, prompt detection and destruction of symptomatic palms, and replanting with less susceptible varieties or crop species. Advances in technology such as loop mediated isothermal amplification (LAMP) for detection and tracking of phytoplasma DNA in plants and insects, remote sensing for identifying symptomatic palms, and the advent of clustered regularly interspaced short palindromic repeats (CRISPR)-based tools for gene editing and plant breeding are likely to allow rapid progress in taxonomy as well as understanding and managing LYD phytoplasma pathosystems. PMID:27833616

  15. ECONOMIC, SOCIAL AND POLITICAL FACTS AND PERSPECTIVES OF 2017

    Directory of Open Access Journals (Sweden)

    Liviu RADU

    2017-05-01

    Full Text Available Following the turbulent year of 2016, with deep geopolitical changes, the new year of 2017 promises to be full of challenges in what concerns the economic, social, political and geostrategic area. The key events of the last year (the Brexit, the elections in the USA, the events in Turkey, the force demonstrations of Russia, the situation of the migration wave etc. shall have an impact on the global economic development and on the repositioning of its main actors. This paperwork intends to analyze the main consequences of the recent events on the short term progress in what concerns the economic, social, political and geostrategic area. We hereby intend to review the facts and the main potential progress on the economic status of this year which was so complicated, both for the European Union and for every member of it.

  16. Connexin 43 astrocytopathy linked to rapidly progressive multiple sclerosis and neuromyelitis optica.

    Directory of Open Access Journals (Sweden)

    Katsuhisa Masaki

    Full Text Available BACKGROUND: Multiple sclerosis (MS and neuromyelitis optica (NMO occasionally have an extremely aggressive and debilitating disease course; however, its molecular basis is unknown. This study aimed to determine a relationship between connexin (Cx pathology and disease aggressiveness in Asian patients with MS and NMO. METHODS/PRINCIPAL FINDINGS: Samples included 11 autopsied cases with NMO and NMO spectrum disorder (NMOSD, six with MS, and 20 with other neurological diseases (OND. Methods of analysis included immunohistochemical expression of astrocytic Cx43/Cx30, oligodendrocytic Cx47/Cx32 relative to AQP4 and other astrocytic and oligodendrocytic proteins, extent of demyelination, the vasculocentric deposition of complement and immunoglobulin, and lesion staging by CD68 staining for macrophages. Lesions were classified as actively demyelinating (n=59, chronic active (n=58 and chronic inactive (n=23. Sera from 120 subjects including 30 MS, 30 NMO, 40 OND and 20 healthy controls were examined for anti-Cx43 antibody by cell-based assay. Six NMO/NMOSD and three MS cases showed preferential loss of astrocytic Cx43 beyond the demyelinated areas in actively demyelinating and chronic active lesions, where heterotypic Cx43/Cx47 astrocyte oligodendrocyte gap junctions were extensively lost. Cx43 loss was significantly associated with a rapidly progressive disease course as six of nine cases with Cx43 loss, but none of eight cases without Cx43 loss regardless of disease phenotype, died within two years after disease onset (66.7% vs. 0%, P=0.0090. Overall, five of nine cases with Cx43 loss and none of eight cases without Cx43 loss had distal oligodendrogliopathy characterized by selective myelin associated glycoprotein loss (55.6% vs. 0.0%, P=0.0296. Loss of oligodendrocytic Cx32 and Cx47 expression was observed in most active and chronic lesions from all MS and NMO/NMOSD cases. Cx43-specific antibodies were absent in NMO/NMOSD and MS patients. CONCLUSIONS

  17. Economic diplomacy and the impact of energy issues on the international relations at the beginning of the XXI century

    Directory of Open Access Journals (Sweden)

    Alexandru GRIBINCEA

    2015-12-01

    Full Text Available One of the essential components of state power in all times was and is the access to resources - land, water and energy. However, with technical and scientific progress, the rapid growth of industrial production, the transition from fossil fuels (coal and oil that determines the role and place in developing countries lies with a separate energy resources. The crucial role of hydrocarbons, which became the basis for the development of the modern economy, was mostly manifested during the Second World War, when the outcome of battles depended on largely stable supplies of crude oil and the possibility of producing fuel at scale. Highlighting the political component of energy security and growing interdependence between the economic and political aspects imposed by the necessity to analyze trends in international economic relations under current energy conditions.

  18. The Impact of the Economic Transition on the Development of Economic Freedom – Case of Poland

    Directory of Open Access Journals (Sweden)

    Anna Stepniak-Kucharska

    2015-06-01

    Full Text Available The changes in the Polish socio-economic system, initiated at the turn of 1989 and 1990, led to a systematic increase in the liberalization of economy and thereby the rise of the level of economic freedom. The aim of this paper is to examine the impact of the economic transition on the development of economic freedom in Poland. The analysis, carried out in the period 1995-2015, was conducted on the basis of the chain-linked Economic Freedom Index by the Fraser Institute and the Index of Economic Freedom of the Heritage Foundation and the Wall Street Journal. The analysis indicates that: (1 Poland cannot be considered as a country that is fully free economically, but the transition of its economic system has resulted in a rapid growth of economic freedom. (2 The impact of transition varies for different areas (sub-indices of the economy. (3 The European economic integration stimulated the increase of EFI, but the economic crisis did not decrease the level of economic freedom.

  19. The progress of mutation breeding for ornamental plants in China

    International Nuclear Information System (INIS)

    Jin Shouming

    1994-02-01

    In China, research on mutation breeding of ornamental plants was begun in the late 70's. In the past decade, about 40 plant species were tested, and hundreds of useful mutants were obtained. At least 63 mutant varieties have been produced, approved and released for cultivation in rose, chrysanthemum, canna, dahlia, bougainvillea and lotus. A rapid progress in methodology and technology of induced mutation breeding has been achieved, particularly in the selection of starting material, determination of suitable exposure and irradiation dose, expression and isolation of somatic mutation etc. In the future it is necessary to develop more plant species and mutation varieties to improve the mutation breeding method and to raise the economic benefit. Along with the development of China's economy and improvement of people's living standard more and more new varieties of ornamental plants will be required. In view of the good beginning, rich germplasm resource and favorable conditions, the prospect of mutation breeding for ornamental plants in China is very encouraging

  20. Economic evaluation of reprocessing

    International Nuclear Information System (INIS)

    1979-02-01

    This paper presents a progress report of work undertaken relevant to the economic evaluation of reprocessing. It sets out the assumptions to be made for the preparation of the economic ''phase diagram'' - a plot of fast reactor premium against uranium (U 3 O 8 ) price. The paper discusses the assumptions to be made in respect of present worth methodology, LWR fuel logistics, U 3 O 8 price, enrichment tails, plutonium values, fast reactor premium and proposes a set of reference costs to be used for the preparation of the phase diagram

  1. Acute HIV infection with rapid progression to AIDS

    Directory of Open Access Journals (Sweden)

    Marcio de Oliveira Silva

    Full Text Available Acute HIV infection is rarely recognized as the signs and symptoms are normally unspecific and can persist for days or weeks. The normal HIV course is characterized by a progressive loss of CD4+ cells, which normally leads to severe immunodeficiency after a variable time interval. The mean time from initial infection to development of clinical AIDS is approximately 8-10 years, but it is variable among individuals and depends on a complex interaction between virus and host. Here we describe an extraordinary case of a man who developed Pneumocisits jiroveci pneumonia within one month after sexual exposure to HIV-1, and then presented with 3 consecutive CD4 counts bellow 200 cells/mm³ within 3 months, with no other opportunistic disease. Although antiretroviral therapy (AZT+3TC+ATZ/r was started, with full adherence of the patient, and genotyping indicating no primary antiretroviral resistance mutations, he required more than six months to have a CD4 restoration to levels above 200 cells/mm³ and 10 months to HIV-RNA to become undetectable.

  2. Improving early cycle economic evaluation of diagnostic technologies.

    Science.gov (United States)

    Steuten, Lotte M G; Ramsey, Scott D

    2014-08-01

    The rapidly increasing range and expense of new diagnostics, compels consideration of a different, more proactive approach to health economic evaluation of diagnostic technologies. Early cycle economic evaluation is a decision analytic approach to evaluate technologies in development so as to increase the return on investment as well as patient and societal impact. This paper describes examples of 'early cycle economic evaluations' as applied to diagnostic technologies and highlights challenges in its real-time application. It shows that especially in the field of diagnostics, with rapid technological developments and a changing regulatory climate, early cycle economic evaluation can have a guiding role to improve the efficiency of the diagnostics innovation process. In the next five years the attention will move beyond the methodological and analytic challenges of early cycle economic evaluation towards the challenge of effectively applying it to improve diagnostic research and development and patient value. Future work in this area should therefore be 'strong on principles and soft on metrics', that is, the metrics that resonate most clearly with the various decision makers in this field.

  3. Introduction to health economics and decision-making: Is economics relevant for the frontline clinician?

    Science.gov (United States)

    Goeree, Ron; Diaby, Vakaramoko

    2013-12-01

    In a climate of escalating demands for new health care services and significant constraints on new resources, the disciplines of health economics and health technology assessment (HTA) have increasingly been turned to as explicit evidence-based frameworks to help make tough health care access and reimbursement decisions. Health economics is the discipline of economics concerned with the efficient allocation of health care resources, essentially trying to maximize health benefits to society contingent upon available resources. HTA is a broader field drawing upon several disciplines, but which relies heavily upon the tools of health economics and economic evaluation. Traditionally, health economics and economic evaluation have been widely used at the political (macro) and local (meso) decision-making levels, and have progressively had an important role even at informing individual clinical decisions (micro level). The aim of this paper is to introduce readers to health economics and discuss its relevance to frontline clinicians. Particularly, the content of the paper will facilitate clinicians' understanding of the link between economics and their medical practice, and how clinical decision-making reflects on health care resource allocation. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. Recent progress in sodium technology

    Energy Technology Data Exchange (ETDEWEB)

    Hallett, W. J.

    1963-10-15

    Progress over the past year in U. S. laboratories studying some of the materials and engineering problems that must be resolved in bringing the technology of sodium to an economically and technically attractive point is reviewed. The status of sodium cooled power reactors in the U. S. is described. (P.C.H.)

  5. Chronic progressive lymphoedema in draught horses.

    Science.gov (United States)

    de Keyser, K; Janssens, S; Buys, N

    2015-05-01

    The objective of this review was to summarise and evaluate the current state of knowledge about chronic progressive lymphoedema in draught horses. Clinical signs of this multifactorial disorder are mainly restricted to the lower limbs, comprising progressively deteriorating skin, swelling and deformation. Although typical lesions were first reported at the beginning of the 20th century, chronic progressive lymphoedema was recognised as a specific syndrome only in 2003, and since then research has driven forward. Despite the high prevalence in some breeds and the serious economic impact, the pathogenesis is not fully understood, and the available treatment options remain symptomatic and noncurative. There is a need to improve diagnostic techniques and to develop selection tools. © 2014 EVJ Ltd.

  6. Rapidity resummation for B-meson wave functions

    Directory of Open Access Journals (Sweden)

    Shen Yue-Long

    2014-01-01

    Full Text Available Transverse-momentum dependent (TMD hadronic wave functions develop light-cone divergences under QCD corrections, which are commonly regularized by the rapidity ζ of gauge vector defining the non-light-like Wilson lines. The yielding rapidity logarithms from infrared enhancement need to be resummed for both hadronic wave functions and short-distance functions, to achieve scheme-independent calculations of physical quantities. We briefly review the recent progress on the rapidity resummation for B-meson wave functions which are the key ingredients of TMD factorization formulae for radiative-leptonic, semi-leptonic and non-leptonic B-meson decays. The crucial observation is that rapidity resummation induces a strong suppression of B-meson wave functions at small light-quark momentum, strengthening the applicability of TMD factorization in exclusive B-meson decays. The phenomenological consequence of rapidity-resummation improved B-meson wave functions is further discussed in the context of B → π transition form factors at large hadronic recoil.

  7. PRO-QUEST: a rapid assessment method based on progressive saturation for quantifying exchange rates using saturation times in CEST.

    Science.gov (United States)

    Demetriou, Eleni; Tachrount, Mohamed; Zaiss, Moritz; Shmueli, Karin; Golay, Xavier

    2018-03-05

    To develop a new MRI technique to rapidly measure exchange rates in CEST MRI. A novel pulse sequence for measuring chemical exchange rates through a progressive saturation recovery process, called PRO-QUEST (progressive saturation for quantifying exchange rates using saturation times), has been developed. Using this method, the water magnetization is sampled under non-steady-state conditions, and off-resonance saturation is interleaved with the acquisition of images obtained through a Look-Locker type of acquisition. A complete theoretical framework has been set up, and simple equations to obtain the exchange rates have been derived. A reduction of scan time from 58 to 16 minutes has been obtained using PRO-QUEST versus the standard QUEST. Maps of both T 1 of water and B 1 can simply be obtained by repetition of the sequence without off-resonance saturation pulses. Simulations and calculated exchange rates from experimental data using amino acids such as glutamate, glutamine, taurine, and alanine were compared and found to be in good agreement. The PRO-QUEST sequence was also applied on healthy and infarcted rats after 24 hours, and revealed that imaging specificity to ischemic acidification during stroke was substantially increased relative to standard amide proton transfer-weighted imaging. Because of the reduced scan time and insensitivity to nonchemical exchange factors such as direct water saturation, PRO-QUEST can serve as an excellent alternative for researchers and clinicians interested to map pH changes in vivo. © 2018 International Society for Magnetic Resonance in Medicine.

  8. Economic liberalization and globalization vs. India's poor

    OpenAIRE

    Oschinski, Matthias

    2003-01-01

    Today, many in the national and international NGO community perceive globalization and economic liberalization as a threat claiming that it widens inequalities and increases overall poverty. While it is true that inequality is on the rise in a rapidly globalizing world the real culprit is not globalization itself but rather a lack of economic reforms and economic liberalization. This paper aims to show that many in the international NGO community confuse cause and effect. The root cause of po...

  9. THE CORRELATION BETWEEN RESEARCH AND DEVELOPMENT AND THE ECONOMIC GROWTH IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Dragomir Laurentiu

    2008-05-01

    Full Text Available The increasing productivity of production factors, due to progresses in science and technology is today the engine of economic growth. The economic theory managed to endogenize the technical progress, first as a result of the unintended activities of firms, then as the result of profit driven behaviour of economic agents. In globalization the stock of knowledge becomes available also to developing countries and the production technologies and their employment are more democratic regarding the availability. For the developing countries it still remains the problem of financial resources and availability. Developing new technologies has a prohibitive costs, at least until the moment in which large scale production allows for the reduction of costs. Long term economic growth will depend on the creation of global technology stock, including the leverage effect of sustained RxD. In this paper we will approach the progress of Romania in the area of knowledge base economy, especially regarding the policies in the RxD sector.

  10. Progress in pulsed power fusion

    Energy Technology Data Exchange (ETDEWEB)

    Quintenz, J P; Adams, R G; Bailey, J E [Sandia Labs., Albuquerque, NM (United States); and others

    1997-12-31

    Pulsed power offers an efficient, high energy, economical source of x-rays for inertial confinement fusion (ICF) research. Two main approaches to ICF driven with pulsed power accelerators are pursued: intense light ion beams and z-pinches. Recent progress in each approach and plans for future development is described. (author). 2 figs., 10 refs.

  11. Progress in pulsed power fusion

    International Nuclear Information System (INIS)

    Quintenz, J.P.; Adams, R.G.; Bailey, J.E.

    1996-01-01

    Pulsed power offers an efficient, high energy, economical source of x-rays for inertial confinement fusion (ICF) research. Two main approaches to ICF driven with pulsed power accelerators are pursued: intense light ion beams and z-pinches. Recent progress in each approach and plans for future development is described. (author). 2 figs., 10 refs

  12. [Reasearch progress in health economic evaluation of colorectal cancer screening in China].

    Science.gov (United States)

    Huang, Huiyao; Shi, Jufang; Dai, Min

    2015-08-01

    Burden of colorectal cancer is rising in China. More attention and financial input have been paid to it by central government that colorectal cancer screening program has been carried out recently in many areas in China. Diversity of screening strategies and limited health resources render selecting the best strategy in a population-wide program a challenging task that economy was also required to be considered except safety and efficacy. To provide a reference for the subsequent further economic evaluation, here we reviewed the evidence available on the economic evaluation of colorectal cancer screening in China. Meanwhile, information related to screening strategies, participation and mid-term efficacy of screening, information and results on economic evaluation were extracted and summarized. Three of the four studies finally included evaluated strategies combining immunochemical fecel occult blood test (iFOBT) with high-risk factor questionnaire as initial screening, colonoscopy as diagnostic screening. There was a consensus regarding the efficacy and effectiveness of screening compared to no screening. Whereas the lack and poor comparability between studies, multi-perspective and multi-phase economic evaluation of colorectal cancer screening is needed, relying on current population-based screening program to conduct a comprehensive cost accounting.

  13. Governance through Economic Paradigms: Addressing Climate Change by Accounting for Health

    Directory of Open Access Journals (Sweden)

    Kristine Belesova

    2016-12-01

    Full Text Available Climate change is a major challenge for sustainable development, impacting human health, wellbeing, security, and livelihoods. While the post-2015 development agenda sets out action on climate change as one of the Sustainable Development Goals, there is little provision on how this can be achieved in tandem with the desired economic progress and the required improvements in health and wellbeing. This paper examines synergies and tensions between the goals addressing climate change and economic progress. We identify reductionist approaches in economics, such as ‘externalities’, reliance on the metric of the Gross Domestic Product, positive discount rates, and short-term profit targets as some of the key sources of tensions between these goals. Such reductionist approaches could be addressed by intersectoral governance mechanisms. Health in All Policies, health-sensitive macro-economic progress indicators, and accounting for long-term and non-monetary values are some of the approaches that could be adapted and used in governance for the SDGs. Policy framing of climate change and similar issues should facilitate development of intersectoral governance approaches.

  14. Greed and Grievance: Economic Agendas in Civil Wars | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Current scholarship on civil wars and transitions from war to peace has made significant progress in understanding the political dimensions of internal conflict. However, the economic motivations spurring political violence have been comparatively neglected. This pathbreaking book identifies the economic and social factors ...

  15. Coping with the Global Economic Crisis: A Challenge to Technical ...

    African Journals Online (AJOL)

    There is rapid transformation of the economics of the developed countries of the ... economic crisis affecting both the developing and underdeveloped countries of ... creating new demands for more adaptable, multi-skilled and creative labour.

  16. Progressive outer retinal necrosis presenting as cherry red spot.

    Science.gov (United States)

    Yiu, Glenn; Young, Lucy H

    2012-10-01

    To report a case of progressive outer retinal necrosis (PORN) presenting as a cherry red spot. Case report. A 53-year-old woman with recently diagnosed HIV and varicella-zoster virus (VZV) aseptic meningitis developed rapid sequential vision loss in both eyes over 2 months. Her exam showed a "cherry red spot" in both maculae with peripheral atrophy and pigmentary changes, consistent with PORN. Due to her late presentation and the rapid progression of her condition, she quickly developed end-stage vision loss in both eyes. PORN should be considered within the differential diagnosis of a "cherry red spot." Immune-deficient patients with a history of herpetic infection who present with visual loss warrant prompt ophthalmological evaluation.

  17. Study on the Coupling Coordination Degree between Metropolitan Economic System and Water Environmental System - Taking Beijing as an Example

    Directory of Open Access Journals (Sweden)

    Chen Ming

    2017-01-01

    Full Text Available The generation of metropolis is the inevitable outcome of the development of urbanization to a certain stage. The economy and society of metropolis are in the rapid development, but this process brings great pressure to the ecological environment, especially the water resources environment at the same time. In this paper, the relationship between metropolitan economic system and water environmental system is deeply studied, and the concept of “coupling” is introduced. Based on the framework of “pressure-state-response” (PSR, 12 detailed indexes, such as total population and water consumption per ten thousand Yuan GDP, were selected to construct four subsystems. The coordination degree measurement model has been used to calculate the degree of coupling between the economic system and water environmental system. On this basis, the following conclusions are drawn through the example of Beijing city: (1 In the process of metropolitan development, the economic system and the water environmental system are interrelated and there exist a complex coupling mechanism. (2 With the adjustment of economic structure and the progress of technology, the coupling index between the metropolitan economic system and the water environmental system has been increasing, and this process shows an upward trend

  18. US carbon emissions, technological progress and economic growth since 1870

    International Nuclear Information System (INIS)

    Huntington, H.G.

    2005-01-01

    The long-term US experience emphasises the importance of controlling for electrification and other major technology transformations when evaluating the growth of carbon emissions at different stages of development. Prior to World War I, carbon emissions grew faster than economic growth by 2.3% per year. As electricity use expanded and steam engines became much larger, carbon emissions began to grow slower than economic growth by 1.6% per year. Adjusting to this technological shift, an expanding economy continues to increase carbon emissions by about 9% for each 10% faster growth. There is little evidence of a decline in this elasticity as the income level rises. These results suggest that the USA today will need to find additional policies to curb carbon emissions if it wishes to prevent any further increase in its per capita emissions, and if its per capita economy grows by more than 1.8% per year. (Author)

  19. How to make progress post-Kyoto

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This document provides papers presented during the workshop on ''how to make progress post-Kyoto'', hold at the French Institute of International Relations (IFRI) in Paris on march 19, 2003. The following topics were presented: reflections on Kyoto, guidance for the future, how to make progress post-kyoto, the lessons from the past; the Bonn voyage; US climate policy after Kyoto, elements of success; preparing for widening and deepening the kyoto protocol; capping emissions and costs; absolute versus intensity-based emissions caps; intensity targets in perspective; negotiating commitments for further emission reductions; exploring new tools; defining meaningful participation of developing countries in climate change mitigation; economic and environmental effectiveness of a technology-based climate regime; US participation in the linkage between research and development and climate cooperation; designing a technology strategy; ''greening'' economic development; some critical comments post-Kyoto; the foreign policy perspective of climate negotiations; Kyoto and the double spiral; burden-sharing rules for stabilizing greenhouse gas concentrations and their equity implications. (A.L.B.)

  20. Socio-economic cultural transformations and Depression in elderly people.

    Science.gov (United States)

    Stranieri, Giuseppe; Carabetta, Carmelo

    2015-09-01

    The socio-economic and cultural evolution in the last decades encouraged a significant process of transformation of the life conditions in advanced societies, particularly the average duration of the life of the elderly population, which since the second half of the past century has increased by about 60%, becoming from an average of fifty years to about eighty two for women and eighty for men. This phenomenon enables scholars and in particular demography scholars, to assume that in 2030 the number of elderly persons will reach about two billion worldwide. This development of an increasingly longer life expectancy, justifies the trust in the great progress that characterizes our society. The rapid growth of this segment of population, due to the improved living conditions and the related progress in science, technology and medicine, in addition to its positive aspects, also includes negative elements, which already affect the Welfare State and, more generally, the public administration that is called to fill the gaps that the transformation of the family and kinship networks have treated with indifference. The problems of the increasingly long-lived, is not freed from new elements of negativity related to the physical and mental decline that leads to the development of new diseases in addition to those already present, ans is increasingly motivated to seek the best remedies to shorten or eliminate the diseases of the elderly. In this context, Depression assumes a central dimension which will surely be a central concern for the economic, social and health impact and for the multitude of changes that put in crisis many of the traditional institutions. This work aims to analyze through a careful review of the scientific literature, the causes of the spread of this disease, the diagnostic difficulties and possible solutions for prevention and care.

  1. Tracking Clean Energy Progress 2013

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-01

    Tracking Clean Energy Progress 2013 (TCEP 2013) examines progress in the development and deployment of key clean energy technologies. Each technology and sector is tracked against interim 2020 targets in the IEA Energy Technology Perspectives 2012 2°C scenario, which lays out pathways to a sustainable energy system in 2050. Stark message emerge: progress has not been fast enough; large market failures are preventing clean energy solutions from being taken up; considerable energy efficiency remains untapped; policies need to better address the energy system as a whole; and energy-related research, development and demonstration need to accelerate. Alongside these grim conclusions there is positive news. In 2012, hybrid-electric vehicle sales passed the 1 million mark. Solar photovoltaic systems were being installed at a record pace. The costs of most clean energy technologies fell more rapidly than anticipated.

  2. Constriction of juxta-ductal aorta and rapid progression of obstruction in a newborn

    International Nuclear Information System (INIS)

    Awasthy, Neeraj; Tomar, Munesh; Radhakrishnan, Sitaraman; Iyer, Krishna Subramoney

    2010-01-01

    A 13-day-old baby girl presenting with features of congestive cardiac failure was found to have coarctation of the aorta (CoA) and patent ductus arteriosus (PDA) by echocardiography. Doppler spectral display revealed moderate CoA. Echocardiogram, 12 hours later, showed severe juxtaductal aortic coarctation with spontaneous closure of PDA. This case emphasises the need to keep a close watch on the progress of CoA in the neonatal period, even if the duct has narrowed to a small size thus demonstrating the role of constriction of juxtaductal aorta in pathogenesis of coaractation. Closure of even asmall PDA can cause acute progression CoA in the presence of posterior shelf

  3. Economic evaluation of reprocessing. Indicative UK position

    International Nuclear Information System (INIS)

    1979-05-01

    This paper, which also appears as an Appendix to the final Working Group 4 report, forms part of the overall economic assessment of reprocessing. The indicative national position and illustrative ''phase diagram'' for the United Kingdom is presented. Under conditions pertaining in the United Kingdom the diagram suggests that: if uranium prices rise rapidly the fast reactor would become economic in the decade 1990-2000, if uranium prices rise more slowly, the fast reactor would become economic in the decade 2000-2010

  4. Chronic Subdural Hematoma development in Accelerated phase of Chronic Myeloid Leukaemia presenting with seizure and rapid progression course with fatal outcome

    Directory of Open Access Journals (Sweden)

    Raheja Amol

    2015-06-01

    Full Text Available Occurrence of chronic subdural hematoma (CSDH in leukemia is rare, and most reported cases occurred in relation with acute myeloid leukaemia; however, occurrence is extremely rare in accelerated phase of chronic myelogenous leukaemia (CML. Seizure as presentation of SDH development in CML cases is not reported in literature. Authors report an elderly male, who was diagnosed as CML, accelerated phase of developing SDH. Initially presented to local physician with seizure; urgent CT scan head was advised, but ignored and sensorium rapidly worsened over next day and reported to our emergency department in deeply comatose state, where imaging revealed chronic subdural hematoma with hypoxic brain injury with fatal outcome. Seizure, progressive worsening of headache, vomiting and papilloedema are harbinger of intracranial space occupying lesion and requires CT head in emergency medical department for exclusion, who are receiving treatment of haematological malignancy

  5. Entrepreneurship, technological progress and resource allocation efficiency: a case of China

    NARCIS (Netherlands)

    He, B.; Li, Z.; Vinig, T.

    2010-01-01

    Purpose - The purpose of this paper is to present an analysis of the role of entrepreneurship in promoting China's technological progress and efficiency improvement during the economic reform process of the past two decades. The paper contributes to our understanding of the drivers of economic

  6. DELUSIONS OF PROGRESS: A Case For Reconceptualising ...

    African Journals Online (AJOL)

    A Case For Reconceptualising Environmental Education ... assuming that economic growth and technological progress are ways to a cleaner environment ... overseas teachers came. ... this experience are several: that students .... humanity, but in an African context, they .... cross-cultural connections that recognise this.

  7. The effectiveness of electromagnetic terahertz radiation use in the treatment of patients with rapidly progressive periodontitis

    Directory of Open Access Journals (Sweden)

    Zelenova A.V.

    2015-12-01

    Full Text Available The aim: to increase the efficiency of treatment of patients with rapidly progressive periodontitis (RPP using electromagnetic radiation at terahertz frequencies of molecular spectrum of radiation and absorption of nitric oxide 150,176-150,664 GHz. Material and methods. The study involved 50 patients with RPP, which according to the method of therapy were divided into 2 groups: group 1 included patients receiving conventional therapy, group 2 consisted of patients who, along with traditional therapy received EHF-therapy device "Orbit" YAKUL.941526.001. The control group consisted of 20 healthy subjects with intact periodontium. For the non-invasive study of tissue blood flow in the periodontal tissue Doppler ultrasound was used MiniMax-Doppler-Phono. The study of the microvasculature of periodontitis has been conducted. To determine the reactivity of microvascular periodontal tissue reflex functional tests on the indirect effect of the cold were performed. Results. Reductions achieved values of periodontal indices, especially important index PMA, a significant increase in the linear blood flow indices, decreased pulse pressure gradient and the index followed appropriate reduction to their cold test. Conclusion. The proposed complex therapy can accelerate the relief of inflammation in the periodontal tissues of the complex, to improve the elastic properties of blood vessels, reduce their tone and restore microcirculation in periodontal tissues.

  8. Economic development and industrial structure - an overview

    Energy Technology Data Exchange (ETDEWEB)

    Nordaas, Hildegunn Kyvik

    1997-09-01

    The essay offers a selective review of central issues related to economic growth. The interrelationship between technological progress, capital accumulation, specialisation and industrial structure is emphasised. It is concluded that, first, there is little evidence that industrial structure plays an independent role in growth. Second, economists have been more successful in explaining the consequence of technological progress than the determinants of technological progress. However, even the consequences are not well understood and there is still a long way to go before general and well-documented policy implications can be drawn. (Author)

  9. Socio-economic status, lifestyle and childhood obesity in Gombe ...

    African Journals Online (AJOL)

    Background: Childhood obesity is a complex condition resulting from an interplay of genetic predisposition, environmental factors and socio-economic status. The prevalence has been increasing all over the world, probably due to economic transition and rapid urbanization as well as globalisation. This relationship should ...

  10. [Economics and ethics in public health?].

    Science.gov (United States)

    Blum, R

    1999-01-01

    The topic suggests a conflict between ethics and economy in medical care. It is often argued that today's welfare state in affluent societies with their social insurance systems makes it easier for the doctor to translate ethical demands into reality without being hampered by economic restrictions. Both doctors and patients took advantage of this system of medical care by mingling social guarantees for health with the doctor's income. Hence, medical expenses expanded rapidly, additionally promoted by technical progress in medicine. This entailed a proportionate increase in medical expenses in relation to personal income, especially wage income. Budgets of state authorities were streamlined or deficits became larger. This state of affairs was promoted further by mechanisms of distribution of national income in accordance with the slogan "less state, more market". While national income continued to grow, although at a slower rate, the number of jobless persons grew continually and thus also the social expenses, this was not due, as is usually assumed and pretended, to an economic crisis. Society and economy are facing a crisis of distribution of national income under conditions of technical progress as a job killer, making economic production more productive and efficient. Not taking into account the new challenge of social market economy--the German innovation in market economy creating the economic miracle after World War II--reforms of the system of medical care took place and are still continuing along market principles, particularly the latest German reform law leading to individual contracts between patients and their doctors in respect of cost charging. However, marketing principles promote economy in medicine, but they do not promote medical ethics. Further German guidelines for medical care should take stock of past experiences. There will be more competition in the "growing market of medical care" (private and public) and this will need--as economic

  11. Americans misperceive racial economic equality.

    Science.gov (United States)

    Kraus, Michael W; Rucker, Julian M; Richeson, Jennifer A

    2017-09-26

    The present research documents the widespread misperception of race-based economic equality in the United States. Across four studies ( n = 1,377) sampling White and Black Americans from the top and bottom of the national income distribution, participants overestimated progress toward Black-White economic equality, largely driven by estimates of greater current equality than actually exists according to national statistics. Overestimates of current levels of racial economic equality, on average, outstripped reality by roughly 25% and were predicted by greater belief in a just world and social network racial diversity (among Black participants). Whereas high-income White respondents tended to overestimate racial economic equality in the past, Black respondents, on average, underestimated the degree of past racial economic equality. Two follow-up experiments further revealed that making societal racial discrimination salient increased the accuracy of Whites' estimates of Black-White economic equality, whereas encouraging Whites to anchor their estimates on their own circumstances increased their tendency to overestimate current racial economic equality. Overall, these findings suggest a profound misperception of and unfounded optimism regarding societal race-based economic equality-a misperception that is likely to have any number of important policy implications.

  12. The role of technical progress in the process of recalculating oil reserves

    International Nuclear Information System (INIS)

    Boulard, J.N.

    1999-01-01

    Contrary to the concept of resources (which is essentially a geological one), the notion of reserves designates the quantities that are technically and economically recoverable. Beyond the production-related effect, the reserves therefore evolve over time in accordance with numerous technical and economic parameters. Among these parameters, it can be seen that technical progress plays a considerable role throughout the process of converting resources into reserves, including progress in the identification, accessibility and processing of the resources, and improvements in economic viability. After having tackled the problem of measuring the 'technical progress effects' and citing examples, we demonstrate that the evolution in oil reserves is subject to three types of impact. These are a quantitative impact by significantly improving the recovery rates or making it possible to identify hitherto undetectable oil fields, a qualitative impact by widening the resource base thanks to the adoption of new categories of oil (in particular the so-called 'unconventional' oils) and by carrying out the gradual substitution between these resources of differing qualities. There is also a dynamic impact, through the acceleration of resource availability. Through these three approaches, technical progress makes makes it possible to ensure continuity in oil supply and contributes significantly to the recalculation of reserves. It therefore acts as a compensating factor, counterbalancing the progressive depletion of resources. (author)

  13. Economic convergence and climate policy

    International Nuclear Information System (INIS)

    Ciscar, J.C.; Soria, A.

    2000-01-01

    This paper addresses the relevance of the economic convergence hypotheses between the developing and the developed world in international greenhouse gas (GHG) emissions negotiations. The results are based on a two-region (the OECD and the rest of the world, ROW) neo-classical growth model with exogenous technical progress, different technological diffusion patterns, and a set of geophysical relationships that consider an environmental externality linked to GHG emissions. A game framework is taken into account in the model to capture the strategic interactions between agents. The outcome of the negotiations seems indeed to depend on the economic convergence hypotheses. Faster economic growth of the ROW countries would encourage them to further mitigate carbon emissions. (Author)

  14. Economization of public services sector and its consequences

    OpenAIRE

    Ewa Polak; Waldemar Polak

    2013-01-01

    The work is devoted to the analysis of the process of human life’s economization Processes taking place in the economic sphere nowadays, affect the social changes in the essential way, affect both the condition of an individual and on relationships between people. The main force of the socio-cultural transformation is scientific-technological progress, especially in the communication and transport as well as promoting the principles of governing the liberal market economy by global economic a...

  15. Caffeine, creatine, GRIN2A and Parkinson's disease progression.

    Science.gov (United States)

    Simon, David K; Wu, Cai; Tilley, Barbara C; Lohmann, Katja; Klein, Christine; Payami, Haydeh; Wills, Anne-Marie; Aminoff, Michael J; Bainbridge, Jacquelyn; Dewey, Richard; Hauser, Robert A; Schaake, Susen; Schneider, Jay S; Sharma, Saloni; Singer, Carlos; Tanner, Caroline M; Truong, Daniel; Wei, Peng; Wong, Pei Shieen; Yang, Tianzhong

    2017-04-15

    Caffeine is neuroprotective in animal models of Parkinson's disease (PD) and caffeine intake is inversely associated with the risk of PD. This association may be influenced by the genotype of GRIN2A, which encodes an NMDA-glutamate-receptor subunit. In two placebo-controlled studies, we detected no association of caffeine intake with the rate of clinical progression of PD, except among subjects taking creatine, for whom higher caffeine intake was associated with more rapid progression. We now have analyzed data from 420 subjects for whom DNA samples and caffeine intake data were available from a placebo-controlled study of creatine in PD. The GRIN2A genotype was not associated with the rate of clinical progression of PD in the placebo group. However, there was a 4-way interaction between GRIN2A genotype, caffeine, creatine and the time since baseline. Among subjects in the creatine group with high levels of caffeine intake, but not among those with low caffeine intake, the GRIN2A T allele was associated with more rapid progression (p=0.03). These data indicate that the deleterious interaction between caffeine and creatine with respect to rate of progression of PD is influenced by GRIN2A genotype. This example of a genetic factor interacting with environmental factors illustrates the complexity of gene-environment interactions in the progression of PD. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Constriction of juxta-ductal aorta and rapid progression of obstruction in a newborn

    Directory of Open Access Journals (Sweden)

    Awasthy Neeraj

    2010-01-01

    Full Text Available A 13-day-old baby girl presenting with features of congestive cardiac failure was found to have coarctation of the aorta (CoA and patent ductus arteriosus (PDA by echocardiography. Doppler spectral display revealed moderate CoA. Echocardiogram, 12 hours later, showed severe juxtaductal aortic coarctation with spontaneous closure of PDA. This case emphasises the need to keep a close watch on the progress of CoA in the neonatal period, even if the duct has narrowed to a small size thus demonstrating the role of constriction of juxtaductal aorta in pathogenesis of coaractation. Closure of even asmall PDA can cause acute progression CoA in the presence of posterior shelf.

  17. Rapid promotion and progression of fibrovascular polyps by inflammation and/or hyperplasia in hamster check pouch: implications for carcinogenesis assay.

    Science.gov (United States)

    McGaughey, C; Jensen, J L

    1983-03-01

    Tumor initiation by topical application of 7,12-dimethylbenz[a]anthracene (DMBA) in dimethyl sulfoxide (DMSO) followed by topical application of retinyl acetate (RA), ethylphenylpropiolate, or acetic acid in DMSO at inflammatory and hyperplasiogenic dose regimens caused the rapid promotion of fibrovascular polyps with dysplastic epithelium in hamster cheek pouch. Such lesions did not occur in control animals initiated with DMBA followed by application of DMSO only, where inflammation was also minimal. At the dose regimen employed, RA caused obvious cytotoxicity and tissue destruction. With EPP and AA, there was no histological evidence of tissue destruction. At dose regimens resulting in minimal inflammation and no apparent cytotoxicity, RA promoted almost no polyps, but a higher yield of other tumor types. Thus, inflammation and/or hyperplasia apparently exerted a strong polyp-promoting and progressive influence. This and other differences between the tumorigenic responses of hamster-pouch mucosa and mouse skin suggest that the former supplement the latter in carcinogenic risk assessment.

  18. Structural MRI correlates of amyotrophic lateral sclerosis progression.

    Science.gov (United States)

    Senda, Joe; Atsuta, Naoki; Watanabe, Hirohisa; Bagarinao, Epifanio; Imai, Kazunori; Yokoi, Daichi; Riku, Yuichi; Masuda, Michihito; Nakamura, Ryoichi; Watanabe, Hazuki; Ito, Mizuki; Katsuno, Masahisa; Naganawa, Shinji; Sobue, Gen

    2017-11-01

    Amyotrophic lateral sclerosis (ALS) presents with varying degrees of brain degeneration that can extend beyond the corticospinal tract (CST). Furthermore, the clinical course and progression of ALS varies widely. Brain degeneration detected using structural MRI could reflect disease progression. On study registration, 3-Tesla volumetric MRI and diffusion tensor imaging scans were obtained at baseline in 38 healthy controls and 67 patients with sporadic ALS. Patients had Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R) scores of ≥36 and did not have the chromosome 9, open reading frame 72 repeat expansion. Six months later, changes in ALSFRS-R (ΔALSFRS-R) scores were calculated and patients were grouped into three categories, namely, patients with slow progression with ΔALSFRS-R scores ≤3 (n=19), intermediate progression with ΔALSFRS-R scores =4, 5 and 6 (n=36) and rapid progression with ΔALSFRS-R scores ≥7 (n=12). We analysed voxel-based morphometry and tract-based spatial statistics among these subgroups and controls. In comparison with controls, patients with ALS showed grey matter atrophy and decreased fractional anisotropy beyond the motor cortex and CST, especially in the frontotemporal lobes and basal ganglia. Moreover, the degree of change was highly proportional to ΔALSFRS-R at the 6-month assessment. A more rapid disease progression and poorer functional decline were associated with greater involvement of the extra-motor cortex and basal ganglia, suggesting that the spatial extent of brain involvement can be an indicator of the progression in ALS. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  19. National cultural values: reflections on the formation process of future leaders in international economic cooperation

    Directory of Open Access Journals (Sweden)

    MARIJA NIKOLIC

    2013-12-01

    Full Text Available The trend towards foreign investments in Serbia has been in rapid progress in recent years. The biggest and most valuable numbers of investments are coming from Italy. The authors’ expectation is that the trend of Italian investments in future will continue; therefore it is of high importance for the representatives of both countries’ business sectors to understand and accept differences and similarities to the other country’s business culture. Research of cultural differences between two nations , which are considered like a frame of business culture, helps avoiding possible misunderstandings and improving business cooperation between two countries. Having in mind students of economics and management, on one hand like future leaders of Italian and Serbian business and on other like representatives of the current education value system in the field of economics and management, this study consists of an application of the 7-D Hofstede Model. The application of the model takes place through the administration of two surveys done by students of Serbian Megatrend University, in Belgrade, and Italian Università degli Studi Gabriele d’Annunzio, in Pescara.

  20. Workforce Training and Economic Development Fund: 2014 Annual Progress Report

    Science.gov (United States)

    Iowa Department of Education, 2014

    2014-01-01

    The Workforce Training and Economic Development (WTED) Fund was established in 2003 as part of the Grow Iowa Values Fund and is currently funded through the Iowa Skilled Worker and Job Creation Fund. This fund has become an important source of financing for community college new program innovation, development, and capacity building, particularly…

  1. The political-economic transition and the building of the welfare state in Spain (1975-1986

    Directory of Open Access Journals (Sweden)

    Rafael Muñoz de Bustillo Llorente

    2008-12-01

    Full Text Available This article analyses the economic policy in Spain during the govern- ments of the Spanish political transition from 1975 to 1986. It considers the different areas of economic policy with special emphasis on the development of welfare state issues in this period. Taking into account the difficult economic and political situation in 1975, there were some important advances in social policy and progressive taxation during the period. The transition to democracy in Spain changed the role and size of the public sector above all from 1975 to 1986. The social demands over the political system were possible improvements in the progressive and redistributive policies in education, health, and social programs. Spain’s transition to democracy and the first period of welfare state show a mutually reinforcing and its consequences were the modernization of the Spanish economy. However, from 1986 the economic develop- ment and the progress of welfare state have had a different growth.Key words: Welfare state, Economic transition, Spain.

  2. Towards a Single Market: A 21st Century Vision for Asia Pacific Economic Integration

    Directory of Open Access Journals (Sweden)

    Andrew Elek

    2010-06-01

    Full Text Available APEC leaders can take pride in progress towards free and open trade. There will always be more to do to integrate Asia Pacific economies. 2010 is the time to look beyond border barriers to trade and adopt a new post-Bogor vision of a single market. Traditional border barriers to trade in some sensitive products remain costly, but affect only a rapidly shrinking part of international commerce. Today, it is more efficient to concentrate on problems of communications and logistics, combined with the lack of efficiency, transparency and sometimes arbitrary implementation of economic policies in different economies. The effective constraint on collective action to deal with these problems is not political will. It is limited capacity to design and implement the necessary policy reform. Creating the necessary capacity needs a unifying vision to deal all obstacles to genuine economic integration, that is, to build a single market. In doing so, Asia Pacific governments can learn from the European Union experience. But they need to promote ever-deeper economic integration without relying on a supra-national authority. Like free and open trade, a single market is a vision which can only be approached, rather than reached by any deadline-it is a point of reference for the many things that need to be done to integrate Asia Pacific economies in a meaningful way. Asia Pacific governments should be encouraged to set their own medium-term targets for progress towards well-defined ingredients of a single market. Strict selection criteria should be used to identify options for cooperation which build on what APEC is already doing and which are in line with the priorities of most member economies. An ambitious program to enhance the efficiency of supply chains could set a successful example and generate the confidence to do more.

  3. Clean Energy Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    For the past several years, the IEA and others have been calling for a clean energy revolution to achieve global energy security, economic growth and climate change goals. This report analyses for the first time progress in global clean energy technology deployment against the pathways that are needed to achieve these goals. It provides an overview of technology deployment status, key policy developments and public spending on RDD&D of clean energy technologies.

  4. Does Child Labor Decline with Improving Economic Status?

    Science.gov (United States)

    Edmonds, Eric V.

    2005-01-01

    The rapid economic growth of Vietnam provides an interesting insight into the sharp decline in child labor. A study of the rising economic status of the population across Vietnam shows that children returned to school or stopped working as their family incomes grew. The decline in child labor is steep in poor households as they emerged from…

  5. Cognitive Capitalism: Economic Freedom Moderates the Effects of Intellectual and Average Classes on Economic Productivity.

    Science.gov (United States)

    Coyle, Thomas R; Rindermann, Heiner; Hancock, Dale

    2016-10-01

    Cognitive ability stimulates economic productivity. However, the effects of cognitive ability may be stronger in free and open economies, where competition rewards merit and achievement. To test this hypothesis, ability levels of intellectual classes (top 5%) and average classes (country averages) were estimated using international student assessments (Programme for International Student Assessment; Trends in International Mathematics and Science Study; and Progress in International Reading Literacy Study) (N = 99 countries). The ability levels were correlated with indicators of economic freedom (Fraser Institute), scientific achievement (patent rates), innovation (Global Innovation Index), competitiveness (Global Competitiveness Index), and wealth (gross domestic product). Ability levels of intellectual and average classes strongly predicted all economic criteria. In addition, economic freedom moderated the effects of cognitive ability (for both classes), with stronger effects at higher levels of freedom. Effects were particularly robust for scientific achievements when the full range of freedom was analyzed. The results support cognitive capitalism theory: cognitive ability stimulates economic productivity, and its effects are enhanced by economic freedom. © The Author(s) 2016.

  6. Successful Surgical Management of Retinopathy of Prematurity Showing Rapid Progression despite Extensive Retinal Photocoagulation.

    Science.gov (United States)

    Gadkari, Salil S; Kulkarni, Sucheta R; Kamdar, Rushita R; Deshpande, Madan

    2015-01-01

    The management of retinopathy of prematurity (ROP) can be challenging in preterm babies with a gestational age premature infant presented with "hybrid" zone 1 disease in the right eye and aggressive posterior ROP in the left eye. Both eyes were adequately treated with laser photocoagulation; however, the eyes deteriorated and progressed to stage 4 ROP. Both eyes eventually underwent intravitreal bevacizumab followed by lens sparing vitrectomy with good anatomical and visual outcome. Anticipation of progression despite laser photocoagulation in certain clinical scenarios, frequent follow-up and timely surgical intervention is paramount.

  7. What Lies beyond the Romania’s Economic Development

    Directory of Open Access Journals (Sweden)

    Monica Raileanu-Szeles

    2011-12-01

    Full Text Available This paper analyzes the dynamic of economic development in Romania, underlying the steps already made by Romania on the way of economic development, as well as the causes of theslowness of this long term process. Four dimensions of the economic development are particularly analyzed here, i.e. the GDP, health, education and income inequality, with a great emphasis on the per capita GDP dynamic. The paper also looks at two contemporary challenges of Romania with a considerable impact on economic development – the progress made in the process of EU funds absorption and the income polarization, which is at present a matter of concern for the whole EU. The components of Romania’s economic development are presented in comparison with those of the New Member States.Keywords: economic development, economic growth, Gini.

  8. Effect of welfare and economic performance on good governance outcomes in Pakistan

    OpenAIRE

    MAMMON, Dawood; RABBANI, Huma

    2017-01-01

    Abstract. The paper undertakes a detailed analysis of economic progress and welfare measures in determining good governance outcomes in Pakistan. There is evidence that inequality stifles the capacity of political, economic and social governance by creating an elite class that protect their economic and political interests and undertake legislation primarily to the benefit of ruling elites. Furthermore our results also suggest that economic development empower the economically and socially ex...

  9. Recent progress in gasoline surrogate fuels

    KAUST Repository

    Sarathy, Mani; Farooq, Aamir; Kalghatgi, Gautam T.

    2017-01-01

    Petroleum-derived gasoline is currently the most widely used fuel for transportation propulsion. The design and operation of gasoline fuels is governed by specific physical and chemical kinetic fuel properties. These must be thoroughly understood in order to improve sustainable gasoline fuel technologies in the face of economical, technological, and societal challenges. For this reason, surrogate mixtures are formulated to emulate the thermophysical, thermochemical, and chemical kinetic properties of the real fuel, so that fundamental experiments and predictive simulations can be conducted. Early studies on gasoline combustion typically adopted single component or binary mixtures (n-heptane/isooctane) as surrogates. However, the last decade has seen rapid progress in the formulation and utilization of ternary mixtures (n-heptane/isooctane/toluene), as well as multicomponent mixtures that span the entire carbon number range of gasoline fuels (C4–C10). The increased use of oxygenated fuels (ethanol, butanol, MTBE, etc.) as blending components/additives has also motivated studies on their addition to gasoline fuels. This comprehensive review presents the available experimental and chemical kinetic studies which have been performed to better understand the combustion properties of gasoline fuels and their surrogates. Focus is on the development and use of surrogate fuels that emulate real fuel properties governing the design and operation of engines. A detailed analysis is presented for the various classes of compounds used in formulating gasoline surrogate fuels, including n-paraffins, isoparaffins, olefins, naphthenes, and aromatics. Chemical kinetic models for individual molecules and mixtures of molecules to emulate gasoline surrogate fuels are presented. Despite the recent progress in gasoline surrogate fuel combustion research, there are still major gaps remaining; these are critically discussed, as well as their implications on fuel formulation and engine

  10. Recent progress in gasoline surrogate fuels

    KAUST Repository

    Sarathy, Mani

    2017-12-06

    Petroleum-derived gasoline is currently the most widely used fuel for transportation propulsion. The design and operation of gasoline fuels is governed by specific physical and chemical kinetic fuel properties. These must be thoroughly understood in order to improve sustainable gasoline fuel technologies in the face of economical, technological, and societal challenges. For this reason, surrogate mixtures are formulated to emulate the thermophysical, thermochemical, and chemical kinetic properties of the real fuel, so that fundamental experiments and predictive simulations can be conducted. Early studies on gasoline combustion typically adopted single component or binary mixtures (n-heptane/isooctane) as surrogates. However, the last decade has seen rapid progress in the formulation and utilization of ternary mixtures (n-heptane/isooctane/toluene), as well as multicomponent mixtures that span the entire carbon number range of gasoline fuels (C4–C10). The increased use of oxygenated fuels (ethanol, butanol, MTBE, etc.) as blending components/additives has also motivated studies on their addition to gasoline fuels. This comprehensive review presents the available experimental and chemical kinetic studies which have been performed to better understand the combustion properties of gasoline fuels and their surrogates. Focus is on the development and use of surrogate fuels that emulate real fuel properties governing the design and operation of engines. A detailed analysis is presented for the various classes of compounds used in formulating gasoline surrogate fuels, including n-paraffins, isoparaffins, olefins, naphthenes, and aromatics. Chemical kinetic models for individual molecules and mixtures of molecules to emulate gasoline surrogate fuels are presented. Despite the recent progress in gasoline surrogate fuel combustion research, there are still major gaps remaining; these are critically discussed, as well as their implications on fuel formulation and engine

  11. 50 Years of Independence: Reflections on the Role of Publishing and Progressive African Intellectuals

    Directory of Open Access Journals (Sweden)

    Walter Bgoya

    2014-01-01

    Full Text Available In this contribution, the role of progressive African intellectuals fifty years after independence in the context of African postcolonial, political and socio-economic conditions is examined. African intellectuals have been marginalized by the African state, and progressive intellectuals have been disunited in their struggle for relevance. The possibilities for African intellectual autonomy and international solidarity are shown through a recollection of the flourishing intellectual environment and local publishing output of post-independence Tanzania. The end of that era and the demise of publishing, including in African languages, has negatively impacted African economic and intellectual emancipation and can only be addressed by international solidarity among progressive intellectuals.

  12. [Construction and evaluation of ecological network in Poyang Lake Eco-economic Zone, China.

    Science.gov (United States)

    Chen, Xiao Ping; Chen, Wen Bo

    2016-05-01

    Large-scale ecological patches play an important role in regional biodiversity conservation. However, with the rapid progress of China's urbanization, human disturbance on the environment is becoming stronger. Large-scale ecological patches will degrade not only in quantity, but also in quality, threatening the connections among them due to isolation and seriously affecting the biodiversity protection. Taking Poyang Lake Eco-economic Zone as a case, this paper established the potential ecological corridors by minimum cost model and GIS technique taking the impacts of landscape types, slope and human disturbance into consideration. Then, based on gravity quantitative model, we analyzed the intensity of ecological interactions between patches, and the potential ecological corridors were divided into two classes for sake of protection. Finally, the important ecological nodes and breaking points were identified, and the structure of the potential ecological network was analyzed. The results showed that forest and cropland were the main landscape types of ecological corridor composition, interaction between ecological patches differed obviously and the structure of the composed regional ecological network was complex with high connectivity and closure. It might provide a scientific basis for the protection of biodiversity and ecological network optimization in Poyang Lake Eco-economic Zone.

  13. The Economic Freedom Index : A Review

    OpenAIRE

    Ruperto P. Alonzo

    2002-01-01

    The economic freedom index (EFI) is one of several cross-country yardsticks that incorporate dimensions of progress and well-being that go beyond what conventional economic indicators tell us. It is a composite of 21 indicators that include “personal choice, protection of private property, and freedom of exchange.” It is one of the few measures where the Philippines ranks higher than most of its neighbors; the Philippines was in fact 29th among 123 countries rated for 1999, while neighboring ...

  14. Expanding economic opportunities in protracted displacement

    OpenAIRE

    Miki Takahashi; Michael Moroz; Jonathan Peters; Jason Pronyk; Richard Barltrop

    2018-01-01

    Welcome progress has been made towards realising commitments made by international donors and host country governments to expand economic opportunities for Syrian refugees and host communities in neighbouring countries. However targets and commitments also bring new challenges, and evidence must underpin new policies.

  15. Health impacts of rapid economic changes in Thailand.

    Science.gov (United States)

    Tangcharoensathien, V; Harnvoravongchai, P; Pitayarangsarit, S; Kasemsup, V

    2000-09-01

    The economic crisis in Thailand in July 1997 had major social implications for unemployment, under employment, household income contraction, changing expenditure patterns, and child abandonment. The crisis increased poverty incidence by 1 million, of whom 54% were the ultra-poor. This paper explores and explains the short-term health impact of the crisis, using existing data and some special surveys and interviews for 2 years during 1998-99. The health impacts of the crisis are mixed, some being negative and some being positive. Household health expenditure reduced by 24% in real terms; among the poorer households, institutional care was replaced by self-medication. The pre-crisis rising trend in expenditure on alcohol and tobacco consumption was reversed. Immunization spending and coverage were sustained at a very high level after the crisis, but reports of increases in diphtheria and pertussis indicate declining programme quality. An increase in malaria, despite budget increases, had many causes but was mainly due to reduced programme effectiveness. STD incidence continued the pre-crisis downward trend. Rates of HIV risky sexual behaviour were higher among conscripts than other male workers, but in both groups there was lower condom use with casual partners. HIV serosurveillance showed a continuation of the pre-crisis downward trend among commercial sex workers (CSW, both brothel and non-brothel based), pregnant women and donated blood; this trend was slightly reversed among male STD patients and more among intravenous drug users. Condom coverage among brothel based CSW continued to increase to 97.5%, despite a 72% budget cut in free condom distribution. Poverty and lack of insurance coverage are two major determinants of absence of or inadequate antenatal care, and low birthweight. The Low Income Scheme could not adequately cover the poor but the voluntary Health Card Scheme played a health safety net role for maternal and child health. Low birthweight and

  16. How to make progress post-Kyoto

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This document provides papers presented during the workshop on ''how to make progress post-Kyoto'', hold at the French Institute of International Relations (IFRI) in Paris on march 19, 2003. The following topics were presented: reflections on Kyoto, guidance for the future, how to make progress post-kyoto, the lessons from the past; the Bonn voyage; US climate policy after Kyoto, elements of success; preparing for widening and deepening the kyoto protocol; capping emissions and costs; absolute versus intensity-based emissions caps; intensity targets in perspective; negotiating commitments for further emission reductions; exploring new tools; defining meaningful participation of developing countries in climate change mitigation; economic and environmental effectiveness of a technology-based climate regime; US participation in the linkage between research and development and climate cooperation; designing a technology strategy; ''greening'' economic development; some critical comments post-Kyoto; the foreign policy perspective of climate negotiations; Kyoto and the double spiral; burden-sharing rules for stabilizing greenhouse gas concentrations and their equity implications. (A.L.B.)

  17. Estimating economic losses from earthquakes using an empirical approach

    Science.gov (United States)

    Jaiswal, Kishor; Wald, David J.

    2013-01-01

    We extended the U.S. Geological Survey's Prompt Assessment of Global Earthquakes for Response (PAGER) empirical fatality estimation methodology proposed by Jaiswal et al. (2009) to rapidly estimate economic losses after significant earthquakes worldwide. The requisite model inputs are shaking intensity estimates made by the ShakeMap system, the spatial distribution of population available from the LandScan database, modern and historic country or sub-country population and Gross Domestic Product (GDP) data, and economic loss data from Munich Re's historical earthquakes catalog. We developed a strategy to approximately scale GDP-based economic exposure for historical and recent earthquakes in order to estimate economic losses. The process consists of using a country-specific multiplicative factor to accommodate the disparity between economic exposure and the annual per capita GDP, and it has proven successful in hindcast-ing past losses. Although loss, population, shaking estimates, and economic data used in the calibration process are uncertain, approximate ranges of losses can be estimated for the primary purpose of gauging the overall scope of the disaster and coordinating response. The proposed methodology is both indirect and approximate and is thus best suited as a rapid loss estimation model for applications like the PAGER system.

  18. Malaysian Economic Development: Looking Backwards and Forward

    OpenAIRE

    Hal Hill

    2010-01-01

    This paper provides an analytical and forward-looking overview of Malaysian economic development. Looking back over its 53 years of Independence, we identify the key stylized facts to include the country's generally rapid economic growth and structural change; its consistent openness, especially for merchandize trade and foreign direct investment; its creditable record of macroeconomic management; its consistently high inequality, in spite of the developing world's most consistently implement...

  19. Social Progress in Romania and other Central and Eastern European Non- Eurozone States

    Directory of Open Access Journals (Sweden)

    VIRGINIA CÂMPEANU

    2016-06-01

    Full Text Available Our research paper refers to the social progress achieved in the last 10 years by Romania, Bulgaria, Czech Republic, Croatia, Poland and Hungary as non- Eurozone members (CEE-6, compared to the minimum and maximum levels in the EU-28, depending on their economic development levels. This analysis isa part of the larger-scale study regarding the readinessassessment of Romania and other five Central and Eastern European countries (CEE-6 for accession to the Eurozone in terms of the real convergence. We extended the analysis of the real economic convergence to the sphere of social convergence. The purpose of the extended analysis is to compare the living standards in Romania, CEE-6 and other European Union member states (EU-28 and to draw conclusions on the social convergence as a complement to real economic convergence. Using a new analytical tool, the global composite index “Social Progress Index” at different levels of disaggregation, this article reveals the social gaps between CEE-6 and the EU and identifies strengths, and weaknesses for these countries to achieve social progress on the road to real economic and social convergence with the EU.The aim is to provide to the national decision-makers some milestones to remove weaknesses and to turn threats into opportunities in the future social and economic policies.

  20. HEALTH, EDUCATION AND ECONOMIC GROWTH IN MALAYSIA

    OpenAIRE

    Rahmah Ismaila and Doris Padmini Selvaratnamb

    1999-01-01

    Human capital is vital for the development of a country. Investment in human capital ranges from basic needs expenditure to education and health provision. Economic growth is often used to measure the progress and development of a country. Today other indicators are used to emphasize physical quality of life, for example, education, health and basic needs provision. Using a simultaneous equation model, this paper estimates the relationship between economic growth and human capital variables i...

  1. Nanomaterial-enabled Rapid Detection of Water Contaminants.

    Science.gov (United States)

    Mao, Shun; Chang, Jingbo; Zhou, Guihua; Chen, Junhong

    2015-10-28

    Water contaminants, e.g., inorganic chemicals and microorganisms, are critical metrics for water quality monitoring and have significant impacts on human health and plants/organisms living in water. The scope and focus of this review is nanomaterial-based optical, electronic, and electrochemical sensors for rapid detection of water contaminants, e.g., heavy metals, anions, and bacteria. These contaminants are commonly found in different water systems. The importance of water quality monitoring and control demands significant advancement in the detection of contaminants in water because current sensing technologies for water contaminants have limitations. The advantages of nanomaterial-based sensing technologies are highlighted and recent progress on nanomaterial-based sensors for rapid water contaminant detection is discussed. An outlook for future research into this rapidly growing field is also provided. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Economic competitiveness of nuclear power in China

    International Nuclear Information System (INIS)

    Hu Chuanwen

    2005-01-01

    Development of nuclear power in China has made a good progress. Currently, economic competitiveness of nuclear power compared to fossil-fuelled power plants is one of the major problems which hamper its development. This article presents the economic competitiveness of nuclear power in China with two-level analyses. First, levelized lifetime cost method is adopted for electricity generation cost comparisons. Important factors influencing economic competitiveness of nuclear power are described. Furthermore, a broad economic evaluation of the full fuel chain of nuclear power and fossil-fuelled plants is discussed concerning macro social-economic issues, environmental and health impacts. The comprehensive comparative assessment would be carried out for decision making to implement nuclear power programme. In consideration of external costs and carbon value, the economic competitiveness of nuclear power would be further improved. Facing swift economic growth, huge energy demand and heavy environmental burden, nuclear power could play a significant role in sustainable development in China. (authors)

  3. Multidetector-row CT: economics and workflow

    International Nuclear Information System (INIS)

    Pottala, K.M.; Kalra, M.K.; Saini, S.; Ouellette, K.; Sahani, D.; Thrall, J.H.

    2005-01-01

    With rapid evolution of multidetector-row CT (MDCT) technology and applications, several factors such ad technology upgrade and turf battles for sharing cost and profitability affect MDCT workflow and economics. MDCT workflow optimization can enhance productivity and reduce unit costs as well as increase profitability, in spite of decrease in reimbursement rates. Strategies for workflow management include standardization, automation, and constant assessment of various steps involved in MDCT operations. In this review article, we describe issues related to MDCT economics and workflow. (orig.)

  4. Investment and Employment - Drivers of European Economic Development

    Directory of Open Access Journals (Sweden)

    Cristina BURGHELEA

    2017-04-01

    Full Text Available The economic literature and related specialty practice, the development of the European Economic Community along with the factors determining them (such investments and staff represents a topic that is of great notoriety. This paper shows the role and influence that direct investment in the economy and employment ratio can propagate in the growth of gross domestic product per capita to ensure increased economic sustainability of countries in the European Community. The most important economic effects of FDI on the host economy can be represented by labor productivity growth through knowledge transfer (know-how technology, management skills and marketing term in countries emerging favor progress technological and economic growth. To determine this goal, in the context of economic logic, this research shows the importance of gross domestic product, total and per capita, as a macroeconomic indicator synthetic, and encouraging and using the action of factors that can also provide political steps, organizational and financial, achieving levels attesting social progress and prosperity. The study highlights a Custom Analysis on gross domestic product per capita, direct investment and the proportion of people employed in total for 24 European Union countries in 2014 and also develop an econometric model multifactorial based on system statistics. Research shows utility in making decisions about investment growth in the European Community by attracting a workforce that is in full compliance with state investment policies and by providing a high living standard.

  5. FOREIGN DIRECT INVESTMENT AND ECONOMIC PROGRESS:APPLICATION OF A DYNAMIC MODEL

    Directory of Open Access Journals (Sweden)

    Cyril A. Ogbokor

    2018-01-01

    Full Text Available Capital movements,whether in the form of foreign direct investment or foreignportfolio investment are considered to have a positive multiplier effect on theeconomy.The study contributes to the empirical literature by investigatingwhether foreign direct investment affects economic growth using Namibia as atest centre.The study made use ofvector autoregression methodto examine thisrelationship.A quarterly data covering 1990:Q1 to 2014:Q4 was employed.Theresults found cointegratingrelationships among the four variables that wereinvestigated. The estimated long-run equation also suggests a positive relationshipamongst the variables that have been examined in the study. Surprisingly, noevidence of causality was found pertaining tothe variables assessed in the study.Moreover, real exchange rate and net foreign direct investment contributed moretowards innovations in economic growth during the forecast horizon compared tothe openness index. The study concludes by crafting opportunities for furtherinquiries.

  6. Rapid and sustained cost management

    International Nuclear Information System (INIS)

    Hanson, D.

    2009-01-01

    Accenture helps clients develop comprehensive, process-driven strategies for rapid and sustained cost management that leverage deep insights and analytics. This approach enables companies to gain operating cost advantages by rationalizing, simplifying and automating current operating capabilities. It drives structural cost advantages by optimizing business mix, capital structure, organizational structure and geographic presence. This paper discussed how successful companies achieve high performance during times of economic turmoil. It also discussed the value of the winner's strategy in terms of rapid and sustained cost management (RSCM). It discussed how Accenture operates and its leveraged capabilities, improved efficiency, margins and cash flow while maintaining customer service levels. Building structural advantage and the Accenture difference were also discussed. It was concluded that RSCM is one vital way that Accenture can help companies achieve success. 4 figs

  7. Increased common carotid artery wall thickness is associated with rapid progression of asymptomatic carotid stenosis.

    Science.gov (United States)

    Diomedi, Marina; Scacciatelli, Daria; Misaggi, Giulia; Balestrini, Simona; Balucani, Clotilde; Sallustio, Fabrizio; Di Legge, Silvia; Stanzione, Paolo; Silvestrini, Mauro

    2014-01-01

    This study aimed to identify clinical and ultrasound imaging predictors of progression of carotid luminal narrowing in subjects with asymptomatic moderate internal carotid artery (ICA) stenosis. A total of 571 subjects with asymptomatic moderate (50-69%) ICA stenoses were enrolled. They underwent ultrasound examination at baseline and after 12 months. Demographics, vascular risk factors, medications, plaque characteristics (surface and echogenicity) and common carotid intima-media thickness (IMT) were collected. At the follow-up examination, any change of ICA stenosis was graded in three categories (i) ≥70% to near occlusion, (ii) near occlusion, and (iii) occlusion. Progression of stenosis was defined as an increase in the stenosis degree by at least one category from baseline to follow-up. At 12 months, progression occurred in 142 subjects (prevalence rate 25%). At the multivariable logistic model, pathological IMT values (considered as binary variable: normal: ≤1 mm vs. pathologic: >1 mm) significantly predicted the risk for plaque progression after adjusting the model for possible confounders (OR 2.28, 95% CI 1.18-4.43, P = .014, multivariable logistic model). Our results confirm the role of carotid wall thickening as a marker of atherosclerosis. Carotid IMT measurement should be considered to implement risk stratification in patients with asymptomatic carotid disease.

  8. Economic Enlightenment Revisited: New Results Again Find Little Relationship Between Education and Economic Enlightenment but Vitiate Prior Evidence of the Left Being Worse

    OpenAIRE

    Daniel B. Klein; Zeljka Buturovic

    2011-01-01

    One year ago, we reported the results of a 2008 Zogby survey that purported to gauge economic enlightenment (Buturovic and Klein 2010). Our main result was that college education bore little relationship to economic enlightenment. We also found that that self-identified Progressives and Liberals did much worse than Conservatives and Libertarians, and this finding generated a lot of controversy. Those results were based on eight questions used to gauge economic enlightenment. Most of those eig...

  9. Suppression of Rapidly Progressive Mouse Glomerulonephritis with the Non-Steroidal Mineralocorticoid Receptor Antagonist BR-4628.

    Science.gov (United States)

    Ma, Frank Y; Han, Yingjie; Nikolic-Paterson, David J; Kolkhof, Peter; Tesch, Greg H

    2015-01-01

    Steroidal mineralocorticoid receptor antagonists (MRAs) are effective in the treatment of kidney disease; however, the side effect of hyperkalaemia, particularly in the context of renal impairment, is a major limitation to their clinical use. Recently developed non-steroidal MRAs have distinct characteristics suggesting that they may be superior to steroidal MRAs. Therefore, we explored the benefits of a non-steroidal MRA in a model of rapidly progressive glomerulonephritis. Accelerated anti-glomerular basement membrane (GBM) glomerulonephritis was induced in groups of C57BL/6J mice which received no treatment, vehicle or a non-steroidal MRA (BR-4628, 5mg/kg/bid) from day 0 until being killed on day 15 of disease. Mice were examined for renal injury. Mice with anti-GBM glomerulonephritis which received no treatment or vehicle developed similar disease with severe albuminuria, impaired renal function, glomerular tuft damage and crescents in 40% of glomeruli. In comparison, mice which received BR-4628 displayed similar albuminuria, but had improved renal function, reduced severity of glomerular tuft lesions and a 50% reduction in crescents. The protection seen in BR-4628 treated mice was associated with a marked reduction in glomerular macrophages and T-cells and reduced kidney gene expression of proinflammatory (CCL2, TNF-α, IFN-γ) and profibrotic molecules (collagen I, fibronectin). In addition, treatment with BR-4626 did not cause hyperkalaemia or increase urine Na+/K+ excretion (a marker of tubular dysfunction). The non-steroidal MRA (BR-4628) provided substantial suppression of mouse crescentic glomerulonephritis without causing tubular dysfunction. This finding warrants further investigation of non-steroidal MRAs as a therapy for inflammatory kidney diseases.

  10. Suppression of Rapidly Progressive Mouse Glomerulonephritis with the Non-Steroidal Mineralocorticoid Receptor Antagonist BR-4628.

    Directory of Open Access Journals (Sweden)

    Frank Y Ma

    Full Text Available Steroidal mineralocorticoid receptor antagonists (MRAs are effective in the treatment of kidney disease; however, the side effect of hyperkalaemia, particularly in the context of renal impairment, is a major limitation to their clinical use. Recently developed non-steroidal MRAs have distinct characteristics suggesting that they may be superior to steroidal MRAs. Therefore, we explored the benefits of a non-steroidal MRA in a model of rapidly progressive glomerulonephritis.Accelerated anti-glomerular basement membrane (GBM glomerulonephritis was induced in groups of C57BL/6J mice which received no treatment, vehicle or a non-steroidal MRA (BR-4628, 5mg/kg/bid from day 0 until being killed on day 15 of disease. Mice were examined for renal injury.Mice with anti-GBM glomerulonephritis which received no treatment or vehicle developed similar disease with severe albuminuria, impaired renal function, glomerular tuft damage and crescents in 40% of glomeruli. In comparison, mice which received BR-4628 displayed similar albuminuria, but had improved renal function, reduced severity of glomerular tuft lesions and a 50% reduction in crescents. The protection seen in BR-4628 treated mice was associated with a marked reduction in glomerular macrophages and T-cells and reduced kidney gene expression of proinflammatory (CCL2, TNF-α, IFN-γ and profibrotic molecules (collagen I, fibronectin. In addition, treatment with BR-4626 did not cause hyperkalaemia or increase urine Na+/K+ excretion (a marker of tubular dysfunction.The non-steroidal MRA (BR-4628 provided substantial suppression of mouse crescentic glomerulonephritis without causing tubular dysfunction. This finding warrants further investigation of non-steroidal MRAs as a therapy for inflammatory kidney diseases.

  11. Consumption and environment - ecological economic perspectives

    DEFF Research Database (Denmark)

    Røpke, Inge

    2006-01-01

    motivation for dealing with consumption in ecological economics is presented. Basically, ecological economists agree that there are limits to the material growth of the economy, and that these limits have already been reached or exceeded. As there is an ethical challenge to increase environmental space......Consumption and environment – ecological economic perspectives Summary Research on issues related to consumption and environment has grown rapidly since the middle of the 1990s, and several disciplines as well as transdisciplinary fields have contributed to this development. The present papers...... constitute a small part of this wave of interest, and they are mostly framed as belonging to ecological economics. The collection starts with an introduction to the field of consumption research within ecological economics and then follows a series of papers on more specific issues. The introductionary...

  12. Economic demand predicts addiction-like behavior and therapeutic efficacy of oxytocin in the rat

    Science.gov (United States)

    Bentzley, Brandon S.; Jhou, Thomas C.; Aston-Jones, Gary

    2014-01-01

    Development of new treatments for drug addiction will depend on high-throughput screening in animal models. However, an addiction biomarker fit for rapid testing, and useful in both humans and animals, is not currently available. Economic models are promising candidates. They offer a structured quantitative approach to modeling behavior that is mathematically identical across species, and accruing evidence indicates economic-based descriptors of human behavior may be particularly useful biomarkers of addiction severity. However, economic demand has not yet been established as a biomarker of addiction-like behavior in animals, an essential final step in linking animal and human studies of addiction through economic models. We recently developed a mathematical approach for rapidly modeling economic demand in rats trained to self-administer cocaine. We show here that economic demand, as both a spontaneous trait and induced state, predicts addiction-like behavior, including relapse propensity, drug seeking in abstinence, and compulsive (punished) drug taking. These findings confirm economic demand as a biomarker of addiction-like behavior in rats. They also support the view that excessive motivation plays an important role in addiction while extending the idea that drug dependence represents a shift from initially recreational to compulsive drug use. Finally, we found that economic demand for cocaine predicted the efficacy of a promising pharmacotherapy (oxytocin) in attenuating cocaine-seeking behaviors across individuals, demonstrating that economic measures may be used to rapidly identify the clinical utility of prospective addiction treatments. PMID:25071176

  13. LAG, GAPS AND CONVERGENCES – FIVE CENTURIES OF EUROPEAN ECONOMIC EXPERIENCES

    Directory of Open Access Journals (Sweden)

    Dr. Bogdan MURGESCU

    2010-11-01

    Full Text Available This paper entails the experience of different European countries in what concerns economic gaps storage, “economic lag” and “catching-up the lag time”, confronting economic theories regarding economic growth determinants. Taking into consideration the cases of Denmark and Ireland, which have managed, in different historical periods, to surpass the peripheral condition and relative economic under- development, and to be part of the most developed and prosper group countries; the study evaluates the chances of other countries to realize similar progresses.

  14. Does Rapid and Sustained Economic Growth Lead to Convergence in Health Resources: The Case of China From 1980 to 2010.

    Science.gov (United States)

    Liang, Di; Zhang, Donglan; Huang, Jiayan; Schweitzer, Stuart

    2016-01-01

    China's rapid and sustained economic growth offers an opportunity to ask whether the advantages of growth diffuse throughout an economy, or remain localized in areas where the growth has been the greatest. A critical policy area in China has been the health system, and health inequality has become an issue that has led the government to broaden national health insurance programs. This study investigates whether health system resources and performance have converged over the past 30 years across China's 31 provinces. To examine geographic variation of health system resources and performance at the provincial level, we measure the degree of sigma convergence and beta convergence in indicators of health system resources (structure), health services utilization (process), and outcome. All data are from officially published sources: the China Health Statistics Year Book and the China Statistics Year Book. Sigma convergence is found for resource indicators, whereas it is not observed for either process or outcome indicators, indicating that disparities only narrowed in health system resources. Beta convergence is found in most indicators, except for 2 procedure indicators, reflecting that provinces with poorer resources were catching up. Convergence found in this study probably reflects the mixed outcome of government input, and market forces. Thus, left alone, the equitable distribution of health care resources may not occur naturally during a period of economic growth. Governmental and societal efforts are needed to reduce geographic health variation and promote health equity. © The Author(s) 2016.

  15. Expanding economic opportunities in protracted displacement

    Directory of Open Access Journals (Sweden)

    Miki Takahashi

    2018-02-01

    Full Text Available Welcome progress has been made towards realising commitments made by international donors and host country governments to expand economic opportunities for Syrian refugees and host communities in neighbouring countries. However targets and commitments also bring new challenges, and evidence must underpin new policies.

  16. Socio-economic significance of mangroves in India

    Digital Repository Service at National Institute of Oceanography (India)

    Untawale, A.G.; Wafar, S.

    Mangrove ecosystem is considered ecologically and economically important perhaps due to its high productivity. However, due to the lack of proper scientific knowledge as well as the rapid increase in various developmental pressures along the coastal...

  17. Impact of economic crisis on the intention to move house

    NARCIS (Netherlands)

    Dane, G.Z.; Grigolon, A.B.; Rasouli, S.; Timmermans, H.J.P.

    2016-01-01

    As a result of the economic crisis in 2008, the price of petrol, goods and agricultural products has rapidly increased and cities all over the world started to suffer from high levels of unemployment and lower business survival rates. Due to the economic downturn, the Dutch housing market also

  18. Impact of economic crisis on the intention to move house

    NARCIS (Netherlands)

    Dane, G.Z.; Grigolon, A.B.; Rasouli, S.; Timmermans, H.J.P.

    2014-01-01

    As a result of the economic crisis in 2008, the price of petrol, goods and agricultural products has rapidly increased and cities all over the world started to suffer from high levels of unemployment and lower business survival rates. Due to the economic downturn, the Dutch housing market also

  19. [Indicators to monitor the evolution of the economic crisis and its effects on health and health inequalities. SESPAS report 2014].

    Science.gov (United States)

    Pérez, Glòria; Rodríguez-Sanz, Maica; Domínguez-Berjón, Felicitas; Cabeza, Elena; Borrell, Carme

    2014-06-01

    The economic crisis has adverse effects on determinants of health and health inequalities. The aim of this article was to present a set of indicators of health and its determinants to monitor the effects of the crisis in Spain. On the basis of the conceptual framework proposed by the Commission for the Reduction of Social Health Inequalities in Spain, we searched for indicators of social, economic, and political (structural and intermediate) determinants of health, as well as for health indicators, bearing in mind the axes of social inequality (gender, age, socioeconomic status, and country of origin). The indicators were mainly obtained from official data sources published on the internet. The selected indicators are periodically updated and are comparable over time and among territories (among autonomous communities and in some cases among European Union countries), and are available for age groups, gender, socio-economic status, and country of origin. However, many of these indicators are not sufficiently reactive to rapid change, which occurs in the economic crisis, and consequently require monitoring over time. Another limitation is the lack of availability of indicators for the various axes of social inequality. In conclusion, the proposed indicators allow for progress in monitoring the effects of the economic crisis on health and health inequalities in Spain. Copyright © 2013 SESPAS. Published by Elsevier Espana. All rights reserved.

  20. Challenges of rapid economic growth in China: Reconciling sustainable energy use, environmental stewardship and social development

    International Nuclear Information System (INIS)

    Li Yong; Oberheitmann, Andreas

    2009-01-01

    China aims at quadrupling per-capita GDP by 2020 compared to the year 2000. Without any energy and environmental policy measures, this tremendous economic growth would be associated with a quadrupling of primary energy consumption up to 6.3 billion tons of standard coal equivalents (sce) and energy-related CO 2 -emissions of 13.9 billion tons Against this background, this paper is to set China's need to implement its sustainable development strategy into the quantitative context of the countries economic development and subsequent economic growth-related environmental problems. China is urgently searching for a way to ease the negative implications of economic growth and has committed itself to achieve a level of 3.0 billion ton sce primary energy consumption in 2020. As a consequence, the macro-economic energy intensity has to be reduced by 53% by 2020. A reduction of 53% by 2020 would lead to an energy intensity level 30% points below the year-2000 level of developed countries. As for natural resources, the expected economic growth will lead to an increase of crude oil net-imports up to 455 million ton sce in 2020 and 650 million ton sce in 2030. As for regional income distribution, economic growth helped to decrease existing inequities

  1. Business, Economics, Financial Sciences, and Management

    CERN Document Server

    2011 International Conference on Business, Economics, and Financial Sciences, Management (BEFM 2011)

    2012-01-01

    A series of papers on business, economics, and financial sciences, management selected from International Conference on Business, Economics, and Financial Sciences, Management are included in this volume.   Management in all business and organizational activities is the act of getting people together to accomplish desired goals and objectives using available resources efficiently and effectively. Management comprises planning, organizing, staffing, leading or directing, and controlling an organization (a group of one or more people or entities) or effort for the purpose of accomplishing a goal. Resourcing encompasses the deployment and manipulation of human resources, financial resources, technological resources and natural resources.   The proceedings of BEFM2011 focuses on the various aspects of advances in Business, Economics, and Financial Sciences, Management and provides a chance for academic and industry professionals to discuss recent progress in the area of Business, Economics, and Financial Scienc...

  2. Development of Mobile Educational Game of Economics

    Directory of Open Access Journals (Sweden)

    Indah Rahayu Kurniasari

    2018-05-01

    Full Text Available Along the rapid development of Information and Communication Technology (ICT, learning media are required to undergo renewal. Innovation of learning media that combines modern technology is needed to improve the effectiveness of learning. The research is a Research and Development (R&D. The product result of this research is mobile educational game of economics. This research aims to determine the feasibility of mobile educational game of economics. Media feasibility was assessed based on the results of media-use response questionnaires that given to experts and students. Expert validation result showed that mobile educational game of economics achieved very good judgment. The assessment questionnaires result from the student also stated that the quality and effectiveness of mobile educational game of economics were very good. So, the research concluded that mobile educational game of economics worthy to be used as a media of economics learning.

  3. Rapid Sand Filtration for Best Practical Treatment of Domestic Wastewater Stabilization Pond Effluent

    Science.gov (United States)

    Boatright, D. T.; Lawrence, C. H.

    1977-01-01

    The technical and economic feasibility of constructing and operating a rapid sand filtration sewage treatment system as an adjunct to a waste water stabilization pond is investigated. The study concludes that such units are within the technical and economic constraints of a small community and comply with the EPA criteria. (BT)

  4. Drivers of inequality in Millennium Development Goal progress: a statistical analysis.

    Science.gov (United States)

    Stuckler, David; Basu, Sanjay; McKee, Martin

    2010-03-02

    Many low- and middle-income countries are not on track to reach the public health targets set out in the Millennium Development Goals (MDGs). We evaluated whether differential progress towards health MDGs was associated with economic development, public health funding (both overall and as percentage of available domestic funds), or health system infrastructure. We also examined the impact of joint epidemics of HIV/AIDS and noncommunicable diseases (NCDs), which may limit the ability of households to address child mortality and increase risks of infectious diseases. We calculated each country's distance from its MDG goals for HIV/AIDS, tuberculosis, and infant and child mortality targets for the year 2005 using the United Nations MDG database for 227 countries from 1990 to the present. We studied the association of economic development (gross domestic product [GDP] per capita in purchasing-power-parity), the relative priority placed on health (health spending as a percentage of GDP), real health spending (health system expenditures in purchasing-power-parity), HIV/AIDS burden (prevalence rates among ages 15-49 y), and NCD burden (age-standardised chronic disease mortality rates), with measures of distance from attainment of health MDGs. To avoid spurious correlations that may exist simply because countries with high disease burdens would be expected to have low MDG progress, and to adjust for potential confounding arising from differences in countries' initial disease burdens, we analysed the variations in rates of change in MDG progress versus expected rates for each country. While economic development, health priority, health spending, and health infrastructure did not explain more than one-fifth of the differences in progress to health MDGs among countries, burdens of HIV and NCDs explained more than half of between-country inequalities in child mortality progress (R(2)-infant mortality = 0.57, R(2)-under 5 mortality = 0.54). HIV/AIDS and NCD burdens were also

  5. Drivers of inequality in Millennium Development Goal progress: a statistical analysis.

    Directory of Open Access Journals (Sweden)

    David Stuckler

    2010-03-01

    Full Text Available Many low- and middle-income countries are not on track to reach the public health targets set out in the Millennium Development Goals (MDGs. We evaluated whether differential progress towards health MDGs was associated with economic development, public health funding (both overall and as percentage of available domestic funds, or health system infrastructure. We also examined the impact of joint epidemics of HIV/AIDS and noncommunicable diseases (NCDs, which may limit the ability of households to address child mortality and increase risks of infectious diseases.We calculated each country's distance from its MDG goals for HIV/AIDS, tuberculosis, and infant and child mortality targets for the year 2005 using the United Nations MDG database for 227 countries from 1990 to the present. We studied the association of economic development (gross domestic product [GDP] per capita in purchasing-power-parity, the relative priority placed on health (health spending as a percentage of GDP, real health spending (health system expenditures in purchasing-power-parity, HIV/AIDS burden (prevalence rates among ages 15-49 y, and NCD burden (age-standardised chronic disease mortality rates, with measures of distance from attainment of health MDGs. To avoid spurious correlations that may exist simply because countries with high disease burdens would be expected to have low MDG progress, and to adjust for potential confounding arising from differences in countries' initial disease burdens, we analysed the variations in rates of change in MDG progress versus expected rates for each country. While economic development, health priority, health spending, and health infrastructure did not explain more than one-fifth of the differences in progress to health MDGs among countries, burdens of HIV and NCDs explained more than half of between-country inequalities in child mortality progress (R(2-infant mortality = 0.57, R(2-under 5 mortality = 0.54. HIV/AIDS and NCD burdens were

  6. Fertility in Alberta in a Context of Rapid Economic Growth, 1997-2007

    Directory of Open Access Journals (Sweden)

    Frank Trovato

    2010-01-01

    Full Text Available Historically, birth rates in Alberta have followed closely the trajectory of change experienced by the other Canadian provinces. Its total fertility rate fell during the low point of the 1930s; it increased during the post-War baby boom in the 1950s and sixties, and thereafter fell to sub-replacement levels beginning in the mid 1970s. In recent years, especially since the early 2000s, the birth rate in Alberta has unexpectedly increased, such that by 2007, it had reached 1.90 children per woman---not far from the 2.1 level needed for generational replacement in the long term. During this same period both national and provincial fertility rates fluctuated at levels below those of Alberta (except Saskatchewan and Manitoba, whose rates have been higher. In this study, I examine the historical pattern of fertility change in Alberta, noting similarities and differences with the other provinces. I then look at the association of selected macro level factors (marriage, unemployment, wages, female labour force participation with change in total and parity-specific birth rates between 1997 and 2007, a period of unprecedented economic growth in Alberta. The statistical results show that although marriage is not significantly correlated with change in fertility rates, male and female wages and female labour force participation all show associations consistent with a procyclical interpretation of fertility change --- that is, periods of economic growth are conducive to fertility increase whereas bad economic times lead to reduced fertility.

  7. Fertility in Alberta in a Context of Rapid Economic Growth, 1997-2007

    Directory of Open Access Journals (Sweden)

    Frank Trovato

    2010-12-01

    Full Text Available Historically, birth rates in Alberta have followed closely the trajectory of change experienced by the other Canadian provinces. Its total fertility rate fell during the low point of the 1930s; it increased during the post-War baby boom in the 1950s and sixties, and thereafter fell to subreplacement levels beginning in the mid 1970s. In recent years, especially since the early 2000s, the birth rate in Alberta has unexpectedly increased, such that by 2007, it had reached 1.90 children per woman - not far from the 2.1 level needed for generational replacement in the long term. During this same period both national and provincial fertility rates fluctuated at levels below those of Alberta (except Saskatchewan and Manitoba, whose rates have been higher. In this study, I examine the historical pattern of fertility change in Alberta, noting similarities and differences with the other provinces. I then look at the association of selected macro level factors (marriage, unemployment, wages, female labour force participation with change in total and parity-specific birth rates between 1997 and 2007, a period of unprecedented economic growth in Alberta. The statistical results show that although marriage is not significantly correlated with change in fertility rates, male and female wages and female labour force participation all show associations consistent with a procyclical interpretation of fertility change - that is, periods of economic growth are conducive to fertility increase whereas bad economic times are associated with reduced fertility.

  8. Economic Consequence Analysis of Disasters: The ECAT Software Tool

    Energy Technology Data Exchange (ETDEWEB)

    Rose, Adam; Prager, Fynn; Chen, Zhenhua; Chatterjee, Samrat; Wei, Dan; Heatwole, Nathaniel; Warren, Eric

    2017-04-15

    This study develops a methodology for rapidly obtaining approximate estimates of the economic consequences from numerous natural, man-made and technological threats. This software tool is intended for use by various decision makers and analysts to obtain estimates rapidly. It is programmed in Excel and Visual Basic for Applications (VBA) to facilitate its use. This tool is called E-CAT (Economic Consequence Analysis Tool) and accounts for the cumulative direct and indirect impacts (including resilience and behavioral factors that significantly affect base estimates) on the U.S. economy. E-CAT is intended to be a major step toward advancing the current state of economic consequence analysis (ECA) and also contributing to and developing interest in further research into complex but rapid turnaround approaches. The essence of the methodology involves running numerous simulations in a computable general equilibrium (CGE) model for each threat, yielding synthetic data for the estimation of a single regression equation based on the identification of key explanatory variables (threat characteristics and background conditions). This transforms the results of a complex model, which is beyond the reach of most users, into a "reduced form" model that is readily comprehensible. Functionality has been built into E-CAT so that its users can switch various consequence categories on and off in order to create customized profiles of economic consequences of numerous risk events. E-CAT incorporates uncertainty on both the input and output side in the course of the analysis.

  9. Rapid land use change after socio-economic disturbances: the collapse of the Soviet Union versus Chernobyl

    International Nuclear Information System (INIS)

    Hostert, Patrick; Kuemmerle, Tobias; Sieber, Anika; Prishchepov, Alexander; Lambin, Eric F; Radeloff, Volker C

    2011-01-01

    Land use change is a principal force and inherent element of global environmental change, threatening biodiversity, natural ecosystems, and their services. However, our ability to anticipate future land use change is severely limited by a lack of understanding of how major socio-economic disturbances (e.g., wars, revolutions, policy changes, and economic crises) affect land use. Here we explored to what extent socio-economic disturbances can shift land use systems onto a different trajectory, and whether this can result in less intensive land use. Our results show that the collapse of the Soviet Union in 1991 caused a major reorganization in land use systems. The effects of this socio-economic disturbance were at least as drastic as those of the nuclear disaster in the Chernobyl region in 1986. While the magnitudes of land abandonment were similar in Ukraine and Belarus in the case of the nuclear disaster (28% and 36% of previously farmed land, respectively), the rates of land abandonment after the collapse of the Soviet Union in Ukraine were twice as high as those in Belarus. This highlights that national policies and institutions play an important role in mediating effects of socio-economic disturbances. The socio-economic disturbance that we studied caused major hardship for local populations, yet also presents opportunities for conservation, as natural ecosystems are recovering on large areas of former farmland. Our results illustrate the potential of socio-economic disturbances to revert land use intensification and the important role institutions and policies play in determining land use systems' resilience against such socio-economic disturbances.

  10. Rapid land use change after socio-economic disturbances: the collapse of the Soviet Union versus Chernobyl

    Science.gov (United States)

    Hostert, Patrick; Kuemmerle, Tobias; Prishchepov, Alexander; Sieber, Anika; Lambin, Eric F.; Radeloff, Volker C.

    2011-10-01

    Land use change is a principal force and inherent element of global environmental change, threatening biodiversity, natural ecosystems, and their services. However, our ability to anticipate future land use change is severely limited by a lack of understanding of how major socio-economic disturbances (e.g., wars, revolutions, policy changes, and economic crises) affect land use. Here we explored to what extent socio-economic disturbances can shift land use systems onto a different trajectory, and whether this can result in less intensive land use. Our results show that the collapse of the Soviet Union in 1991 caused a major reorganization in land use systems. The effects of this socio-economic disturbance were at least as drastic as those of the nuclear disaster in the Chernobyl region in 1986. While the magnitudes of land abandonment were similar in Ukraine and Belarus in the case of the nuclear disaster (28% and 36% of previously farmed land, respectively), the rates of land abandonment after the collapse of the Soviet Union in Ukraine were twice as high as those in Belarus. This highlights that national policies and institutions play an important role in mediating effects of socio-economic disturbances. The socio-economic disturbance that we studied caused major hardship for local populations, yet also presents opportunities for conservation, as natural ecosystems are recovering on large areas of former farmland. Our results illustrate the potential of socio-economic disturbances to revert land use intensification and the important role institutions and policies play in determining land use systems' resilience against such socio-economic disturbances.

  11. Rapid land use change after socio-economic disturbances: the collapse of the Soviet Union versus Chernobyl

    Energy Technology Data Exchange (ETDEWEB)

    Hostert, Patrick; Kuemmerle, Tobias; Sieber, Anika [Geography Department, Humboldt-Universitaet zu Berlin, Unter den Linden 6, 10099 Berlin (Germany); Prishchepov, Alexander [Leibniz Institute of Agricultural Development in Central and Eastern Europe (IAMO), Department of Structural Development of Farms and Rural Areas, Theodor-Lieser-Strasse 2, 06120 Halle (Germany); Lambin, Eric F [Earth and Life Institute, Universite catholique de Louvain, place L. Pasteur 3, B-1348 Louvain-la-Neuve (Belgium); Radeloff, Volker C, E-mail: patrick.hostert@geo.hu-berlin.de [Department of Forest and Wildlife Ecology, University of Wisconsin-Madison, 1630 Linden Drive, Madison, WI 53706-1598 (United States)

    2011-10-15

    Land use change is a principal force and inherent element of global environmental change, threatening biodiversity, natural ecosystems, and their services. However, our ability to anticipate future land use change is severely limited by a lack of understanding of how major socio-economic disturbances (e.g., wars, revolutions, policy changes, and economic crises) affect land use. Here we explored to what extent socio-economic disturbances can shift land use systems onto a different trajectory, and whether this can result in less intensive land use. Our results show that the collapse of the Soviet Union in 1991 caused a major reorganization in land use systems. The effects of this socio-economic disturbance were at least as drastic as those of the nuclear disaster in the Chernobyl region in 1986. While the magnitudes of land abandonment were similar in Ukraine and Belarus in the case of the nuclear disaster (28% and 36% of previously farmed land, respectively), the rates of land abandonment after the collapse of the Soviet Union in Ukraine were twice as high as those in Belarus. This highlights that national policies and institutions play an important role in mediating effects of socio-economic disturbances. The socio-economic disturbance that we studied caused major hardship for local populations, yet also presents opportunities for conservation, as natural ecosystems are recovering on large areas of former farmland. Our results illustrate the potential of socio-economic disturbances to revert land use intensification and the important role institutions and policies play in determining land use systems' resilience against such socio-economic disturbances.

  12. STIGLER’S INFLUENTIAL CONTRIBUTION TO ECONOMIC THOUGHT

    Directory of Open Access Journals (Sweden)

    Artidiatun Adji

    2017-01-01

    Full Text Available This paper analyzes George J. Stigler’s influential contributions to economic ideas, specifically on industrial structures, the functioning of markets, the causes and effects of public regulation, the economics of information, and on the development of economic thought. Stigler’s most influential contribution to economic thought came in his work on information theory. Treating information as a valuable commodity, he explained why prices differ for identical goods. From his work, many other theories have been built to explain economic behavior. A considerable number of works on decision making under uncertainty could not have progressed without an understanding of the role of information. His swing of the pendulum in economic regulation constitutes a great turnabout. He started research, known as public choice, which assumes that government policymakers are driven by self-interest rather than pure concern for the public’s welfare. His views have now become those of the mainstream.

  13. The Rocky Road to Paradise: Why Economic Liberalization is Interrupted

    OpenAIRE

    David Barker

    2009-01-01

    Despite evidence that free market policies improve overall welfare, much of the world is making little progress in reducing state economic controls. Short-term transition costs may be the reason. A simple model demonstrates that it may be rational to weight these costs more heavily than the long-term benefits of economic freedom.

  14. Economic policy uncertainty index and economic activity: what causes what?

    Directory of Open Access Journals (Sweden)

    Ivana Lolić

    2017-01-01

    Full Text Available This paper is a follow-up on the Economic Policy Uncertainty (EPU index, developed in 2011 by Baker, Bloom, and Davis. The principal idea of the EPU index is to quantify the level of uncertainty in an economic system, based on three separate pillars: news media, number of federal tax code provisions expiring in the following years, and disagreement amongst professional forecasters on future tendencies of relevant macroeconomic variables. Although the original EPU index was designed and published for the US economy, it had instantly caught the attention of numerous academics and was rapidly introduced in 15 countries worldwide. Extensive academic debate has been triggered on the importance of economic uncertainty relating to the intensity and persistence of the recent crisis. Despite the intensive (mostly politically-motivated debate, formal scientific confirmation of causality running from the EPU index to economic activity has not followed. Moreover, empirical literature has completely failed to conduct formal econometric testing of the Granger causality between the two mentioned phenomena. This paper provides an estimation of the Toda-Yamamoto causality test between the EPU index and economic activity in the USA and several European countries. The results do not provide a general conclusion: causality seems to run in both directions only for the USA, while only in one direction for France and Germany. Having taken into account the Great Recession of 2008, the main result does not change, therefore casting doubt on the index methodology and overall media bias.

  15. Block chain Technology:Concept of Digital Economics

    OpenAIRE

    Ahmed, Ovais

    2017-01-01

    The purpose of the study is to explain about blockchain technology and how to use of blockchain technology for modern economics practices. We focused on this paper to put the light on blockchain usage in some other areas of economy such as, governance and political decision making, public finance, financial institution & stock market trading, global trading and other economic activities. The literature showed that blockchain is rapidly growing at globally and increasing digital money for tran...

  16. Annual report on reactor safety research projects sponsored by the Ministry of Economics and Technology of the Federal Republic of Germany. Reporting period 2005. Progress report

    International Nuclear Information System (INIS)

    2005-01-01

    Within its competence for energy research, the Bundesministerium fuer Wirtschaft und Technology (BMWi) (Federal Ministry of Economics and Technology) sponsors investigations into the safety of nuclear power plants. The objective of these investigations is to provide fundamental knowledge, procedures and methods to contribute to realistic safety assessments of nuclear installations, to the further development of safety technology and to make use of the potential of innovative safety-related approaches. The Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, by order of the BMWi, continuously issues information on the status of such investigations by publishing semi-annual and annual progress reports within the series of GRS-F-Fortschrittsberichte (GRS-F-Progress Reports). Each progress report represents a compilation of individual reports about the objectives, work performed, results achieved, next steps of the work etc. The individual reports are prepared in a standard form by the research organisations themselves as documentation of their progress in work and are published by the Research Management Division of GRS within the framework of general information on the progress in reactor safety research. The compilation of the reports is classified according to general topics related to reactor safety research. Further, use is made of the classification system 'Joint Safety Research Index' of the CEC (Commission of the European Communities). The reports are arranged in sequence of their project numbers. It has to be pointed out that the authors of the reports are responsible for the contents of this compilation. The BMWi does not take any responsibility for the correctness, exactness and completeness of the information nor for the observance of private claims of third parties. (orig.)

  17. Annual report on reactor safety research projects sponsored by the Ministry of Economics and Technology of the Federal Republic of Germany. Reporting period 2007. Progress report

    International Nuclear Information System (INIS)

    2007-01-01

    Within its competence for energy research the Federal Ministry of Economics and Technology (BMWi) sponsors research projects on the safety of nuclear power plants currently in operation. The objective of these projects is to provide fundamental knowledge, procedures and methods to contribute to realistic safety assessments of nuclear installations, to the further development of safety technology and to make use of the potential of innovative safety-related approaches. The Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, by order of the BMWi, continuously issues information on the status of such research projects by publishing semi-annual and annual progress reports within the series of GRS-F-Fortschrittsberichte (GRS-F-Progress Reports). Each progress report represents a compilation of individual reports about the objectives, work performed, results achieved, next steps of the work etc. The individual reports are prepared in a standard form by the research organisations themselves as documentation of their progress in work. The progress reports are published by the Research Management Division of GRS. The reports as of the year 2000 are available in the Internet-based information system on results and data of reactor safety research (http://www.grs-fbw.de). The compilation of the reports is classified according to the classification system 'Joint Safety Research Index (JSRI)'. The reports are arranged in sequence of their project numbers. It has to be pointed out that the authors of the reports are responsible for the contents of this compilation. The BMWi does not take any responsibility for the correctness, exactness and completeness of the information nor for the observance of private claims of third parties. (orig.)

  18. Annual report on reactor safety research projects sponsored by the Ministry of Economics and Labour of the Federal Republic of Germany. Reporting period 2004. Progress report

    International Nuclear Information System (INIS)

    2004-01-01

    Within its competence for energy research, the Bundesministerium fuer Wirtschaft und Technology (BMWi) (Federal Ministry of Economics and Technology) sponsors investigations into the safety of nuclear power plants. The objective of these investigations is to provide fundamental knowledge, procedures and methods to contribute to realistic safety assessments of nuclear installations, to the further development of safety technology and to make use of the potential of innovative safety-related approaches. The Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, by order of the BMWi, continuously issues information on the status of such investigations by publishing semi-annual and annual progress reports within the series of GRS-F-Fortschrittsberichte (GRS-F-Progress Reports). Each progress report represents a compilation of individual reports about the objectives, work performed, results achieved, next steps of the work etc. The individual reports are prepared in a standard form by the research organisations themselves as documentation of their progress in work and are published by the Research Management Division of GRS within the framework of general information on the progress in reactor safety research. The compilation of the reports is classified according to general topics related to reactor safety research. Further, use is made of the classification system 'Joint Safety Research Index' of the CEC (Commission of the European Communities). The reports are arranged in sequence of their project numbers. It has to be pointed out that the authors of the reports are responsible for the contents of this compilation. The BMWi does not take any responsibility for the correctness, exactness and completeness of the information nor for the observance of private claims of third parties. (orig.)

  19. Annual report on reactor safety research projects sponsored by the Ministry of Economics and Labour of the Federal Republic of Germany. Reporting period 2004. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    Within its competence for energy research, the Bundesministerium fuer Wirtschaft und Technology (BMWi) (Federal Ministry of Economics and Technology) sponsors investigations into the safety of nuclear power plants. The objective of these investigations is to provide fundamental knowledge, procedures and methods to contribute to realistic safety assessments of nuclear installations, to the further development of safety technology and to make use of the potential of innovative safety-related approaches. The Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, by order of the BMWi, continuously issues information on the status of such investigations by publishing semi-annual and annual progress reports within the series of GRS-F-Fortschrittsberichte (GRS-F-Progress Reports). Each progress report represents a compilation of individual reports about the objectives, work performed, results achieved, next steps of the work etc. The individual reports are prepared in a standard form by the research organisations themselves as documentation of their progress in work and are published by the Research Management Division of GRS within the framework of general information on the progress in reactor safety research. The compilation of the reports is classified according to general topics related to reactor safety research. Further, use is made of the classification system 'Joint Safety Research Index' of the CEC (Commission of the European Communities). The reports are arranged in sequence of their project numbers. It has to be pointed out that the authors of the reports are responsible for the contents of this compilation. The BMWi does not take any responsibility for the correctness, exactness and completeness of the information nor for the observance of private claims of third parties. (orig.)

  20. Changing Identities and Socio Economic Strategies

    DEFF Research Database (Denmark)

    Singla, Rashmi; Fabricius, Anne Sophie; Holm, Anne

    Changing Identities and Socio Economic Strategies: South Asian Diasporic Youth in Scandinavia   Rashmi Singla,  Anne Sophie Fabricius & Anne Holm This paper throws light on the rapid cultural transformations as well as continuity among the South Asian youth in Scandinavia, primarily in Denmark....... Based on two interdisciplinary empirical studies, it investigates some socioeconomic aspects of the South Asian diaspora in Denmark. The first longitudinal study explored young adults’ economic strategies in relation to their country of origin. The first wave investigation was conducted in the mid-1990s...

  1. Economic and care considerations of Marfan syndrome.

    Science.gov (United States)

    Blankart, Carl Rudolf; Milstein, Ricarda; Rybczynski, Meike; Schüler, Helke; von Kodolitsch, Yskert

    2016-10-01

    Marfan syndrome is a rare multisystem disease of the connective tissue, which affects multiple organ systems. advances in healthcare have doubled the life-expectancy of patients over the past three decades. to date, there is no comprehensive review that consolidates economic considerations and care for marfan patients. Areas covered: Present research suggests that there may be a link between treatment pattern, disease progression and economic costs of Marfan syndrome. It indicates that an early detection of the disease and preventive interventions achieve a dual aim. From a patient perspective, it may reduce the amount of emergency surgery or intervention, and inpatient stays. In addition, it slows disease progression, lowers lifestyle restrictions, reduces psychological stress, and improves health-related quality of life. Expert commentary: Early detection and preventive measures are likely to achieve a dual aim by simultaneously containing costs and reducing the number and length of inpatient stays.

  2. Structural Change and Economic Development in China and India

    Directory of Open Access Journals (Sweden)

    Vittorio Valli

    2009-06-01

    Full Text Available The comparison of the periods of rapid economic growth in China since 1978 and India since 1992 markedly show different patterns of development and structural change. However, both countries experienced some advantages of "relative economic backwardness" and some aspects of the "fordist model of growth". China had an anticipated and deeper structural change, spurred mainly by economic reforms and the growth of the internal market in the 1980s, and, since the mid-1990s, by a very rapid penetration of its industrial products in the world market. However, a substantial part of China's exports in medium and high tech sectors are due to joint-ventures with foreign multinationals. India had a more balanced structural change and a slower insertion in the world market, although some sectors, such as software, steel, automotive and pharmaceuticals are recently increasing their share in the world markets. Owing to the huge number of micro-enterprises and the great size of the informal sector, India benefited much less than China from the economies of scale and from the third wave of the "fordist model of growth". Both countries, but in particular China, experienced negative externalities of this recent phase of rapid growth, such as higher inequalities, pollution and urban congestion.

  3. [Research progress on fascioliasis].

    Science.gov (United States)

    Liu, Qian; Cheng, Na; Zhou, Yan; Xu, Xue-Nian

    2013-06-01

    Fascioliasis is an important zoonosis caused by Fasciola spp. It can cause pathological damages to human liver and gallbladder, as well as economic loss in animal husbandry. Fascioliasis can be easily misdiagnosed with other hepatobiliary diseases. The appearance of resistance to triclabendazole is an issue problem for fascioliasis control. Therefore, research for better diagnostic methods, effective drugs and vaccines become to the focus of fascioliasis control. This article summarizes the progress on epidemiological status, diagnostic method, therapy, drug resistance, vaccine and omics of fascioliasis.

  4. The Rocky Road to Paradise: Why Economic Liberalization is Interrupted

    Directory of Open Access Journals (Sweden)

    David Barker

    2009-07-01

    Full Text Available Despite evidence that free market policies improve overall welfare, much of the world is making little progress in reducing state economic controls. Short-term transition costs may be the reason. A simple model demonstrates that it may be rational to weight these costs more heavily than the long-term benefits of economic freedom.

  5. Impact of FDI in economic expansion: The Kosovo case

    Directory of Open Access Journals (Sweden)

    Afrim Loku

    2017-11-01

    financial institutions. The persistent trade deficit reflects a weak production base and poor international competitiveness. Reliance on remittances and the widespread informal economy additionally decrease employment incentives, resulting in low labour force participation, especially among women, and high unemployment rates, in particular among young and unskilled workers. Kosovo is at an early stage in building the capacity to cope with competitive pressures and market forces within the Union. No progress was made on improving the quality of education, which is a key driver for improving long-term growth and competitiveness. Foreign direct investment (FDI is widely recognized for its positive impacts on economic growth and transformation (Amerasinghe & Modesto, 2012. FDI may facilitate rapid economic growth in developing countries by increasing savings and investment and by transferring experiences, technologies, and know-how from developed countries (Mott aleba, & Kalirajan, 2010. The impact of FDI on growth may also positively aff ect poverty levels in the host country by increasing employment opportunities and wages (Klein, Aaaron and Hadjimichael, 2011. Kosovo is limited in its ability to attract foreign investment due to the lack of information distribution within global markets, poor international communication regarding its economic environment and opportunities for foreign investment, and the absence of a credit rating by a credible foreign rating agency. Foreign investment inflows have also been hindered by high degrees of corruption, slow and ineffective business environment reforms, lack of transparency, economic inactivity in many sectors, negative perception by foreign investors and diaspora populations, and the failure of institutions to implement and achieve their set objectives. The law has not been implemented because of various factors (such as: bureaucracy costs, long administrative procedures, bribery and favors and all of them have created

  6. Risks of rapid decline renal function in patients with type 2 diabetes

    Institute of Scientific and Technical Information of China (English)

    Yi-Jing; Sheen; Wayne; HH; Sheu

    2014-01-01

    Progressive rising population of diabetes and related nephropathy, namely, diabetic kidney disease and associated end stage renal disease has become a major global public health issue. Results of observational studies indicate that most diabetic kidney disease progresses over decades; however, certain diabetes patients display a rapid decline in renal function, which may lead to renal failure within months. Although the definition of rapid renal function decline remained speculative, in general,it is defined by the decrease of estimated glomerular filtration rate(e GFR) in absolute rate of loss or percent change. Based on the Kidney Disease: Improving Global Outcomes 2012 clinical practice guidelines, a rapid decline in renal function is defined as a sustained declinein e GFR of > 5 m L/min per 1.73 m2 per year. It has been reported that potential factors contributing to a rapid decline in renal function include ethnic/genetic and demographic causes, smoking habits, increased glycated hemoglobin levels, obesity, albuminuria, anemia, low serum magnesium levels, high serum phosphate levels, vitamin D deficiency, elevated systolic blood pressure, pulse pressure, brachial-ankle pulse wave velocity values, retinopathy, and cardiac autonomic neuropathy. This article reviews current literatures in this area and provides insight on the early detection of diabetic subjects who are at risk of a rapid decline in renal function in order to develop a more aggressive approach to renal and cardiovascular protection.

  7. Estimating total economic merit for the Portuguese Holstein cattle population under new economic conditions

    Directory of Open Access Journals (Sweden)

    Joana B.M. Almeida

    2013-12-01

    Full Text Available The objective of this study was to develop a total economic merit index that identifies more profitable animals using Portugal as a case study to illustrate the recent economic changes in milk production. Economic values were estimated following future global prices and EU policy, and taking into consideration the priorities of the Portuguese dairy sector. Economic values were derived using an objective system analysis with a positive approach, that involved the comparison of several alternatives, using real technical and economic data from national dairy farms. The estimated relative economic values revealed a high importance of production traits, low for morphological traits and a value of zero for somatic cell score. According to several future market expectations, three scenarios for milk production were defined: a realistic, a pessimistic and an optimistic setting, each with projected future economic values. Responses to selection and efficiency of selection of the indices were compared to a fourth scenario that represents the current selection situation in Portugal, based on individual estimated breeding values for milk yield. Although profit resulting from sale of milk per average lactation in the optimistic scenario was higher than in the realistic scenario, the volatility of future economic conditions and uncertainty about the future milk pricing system should be considered. Due to this market instability, genetic improvement programs require new definitions of profit functions for the near future. Effective genetic progress direction must be verified so that total economic merit formulae can be adjusted and selection criteria redirected to the newly defined target goals.

  8. Progress toward universal health coverage in ASEAN

    Directory of Open Access Journals (Sweden)

    Hoang Van Minh

    2014-12-01

    Full Text Available Background: The Association of Southeast Asian Nations (ASEAN is characterized by much diversity in terms of geography, society, economic development, and health outcomes. The health systems as well as healthcare structure and provisions vary considerably. Consequently, the progress toward Universal Health Coverage (UHC in these countries also varies. This paper aims to describe the progress toward UHC in the ASEAN countries and discuss how regional integration could influence UHC. Design: Data reported in this paper were obtained from published literature, reports, and gray literature available in the ASEAN countries. We used both online and manual search methods to gather the information and ‘snowball’ further data. Results: We found that, in general, ASEAN countries have made good progress toward UHC, partly due to relatively sustained political commitments to endorse UHC in these countries. However, all the countries in ASEAN are facing several common barriers to achieving UHC, namely 1 financial constraints, including low levels of overall and government spending on health; 2 supply side constraints, including inadequate numbers and densities of health workers; and 3 the ongoing epidemiological transition at different stages characterized by increasing burdens of non-communicable diseases, persisting infectious diseases, and reemergence of potentially pandemic infectious diseases. The ASEAN Economic Community's (AEC goal of regional economic integration and a single market by 2015 presents both opportunities and challenges for UHC. Healthcare services have become more available but health and healthcare inequities will likely worsen as better-off citizens of member states might receive more benefits from the liberalization of trade policy in health, either via regional outmigration of health workers or intra-country health worker movement toward private hospitals, which tend to be located in urban areas. For ASEAN countries, UHC should

  9. Progress toward universal health coverage in ASEAN.

    Science.gov (United States)

    Van Minh, Hoang; Pocock, Nicola Suyin; Chaiyakunapruk, Nathorn; Chhorvann, Chhea; Duc, Ha Anh; Hanvoravongchai, Piya; Lim, Jeremy; Lucero-Prisno, Don Eliseo; Ng, Nawi; Phaholyothin, Natalie; Phonvisay, Alay; Soe, Kyaw Min; Sychareun, Vanphanom

    2014-01-01

    The Association of Southeast Asian Nations (ASEAN) is characterized by much diversity in terms of geography, society, economic development, and health outcomes. The health systems as well as healthcare structure and provisions vary considerably. Consequently, the progress toward Universal Health Coverage (UHC) in these countries also varies. This paper aims to describe the progress toward UHC in the ASEAN countries and discuss how regional integration could influence UHC. Data reported in this paper were obtained from published literature, reports, and gray literature available in the ASEAN countries. We used both online and manual search methods to gather the information and 'snowball' further data. We found that, in general, ASEAN countries have made good progress toward UHC, partly due to relatively sustained political commitments to endorse UHC in these countries. However, all the countries in ASEAN are facing several common barriers to achieving UHC, namely 1) financial constraints, including low levels of overall and government spending on health; 2) supply side constraints, including inadequate numbers and densities of health workers; and 3) the ongoing epidemiological transition at different stages characterized by increasing burdens of non-communicable diseases, persisting infectious diseases, and reemergence of potentially pandemic infectious diseases. The ASEAN Economic Community's (AEC) goal of regional economic integration and a single market by 2015 presents both opportunities and challenges for UHC. Healthcare services have become more available but health and healthcare inequities will likely worsen as better-off citizens of member states might receive more benefits from the liberalization of trade policy in health, either via regional outmigration of health workers or intra-country health worker movement toward private hospitals, which tend to be located in urban areas. For ASEAN countries, UHC should be explicitly considered to mitigate

  10. Water scarcity in the Arabian Peninsula and socio-economic implications

    Science.gov (United States)

    Odhiambo, George O.

    2017-09-01

    The Arabian Gulf, one of the driest parts of the world, is already passing the water scarcity line as defined by the World Health Organization (WHO). The scarcity of renewable water resources and the growing discrepancy between demand and supply of water is a major challenge. Water scarcity is further worsened by rapidly growing demands due to rapid population growth, unsustainable consumption, climate change and weak management institutions and regulations. Water scarcity erodes the socio-economic sustainability of the communities that depend on the depleting storage. In this paper, an analysis of the water security situation within the Arabian Gulf region and the consequent socio-economic implications is presented.

  11. Profitability of a Smallholder Late Season Rapid Multiplication of ...

    African Journals Online (AJOL)

    The study investigated the effects of increasing poultry manure rates on the soil physicochemical properties, crop productivity and economic returns to investment of late season rapid multiplication of cassava stem enterprise at the Teaching and Research Farm, Federal University of Technology, Owerri in the humid ...

  12. Designing Economic Socialization System in the Educational Process of Technological University

    Science.gov (United States)

    Shaidullina, Rimma M.; Amirov, Artur F.; Muhametshin, Vyacheslav S.; Tyncherov, Kamil T.

    2017-01-01

    The relevance of this study is related to the fact that the necessity of compliance between the professional education system and progressive tendencies of world economy development demanded the formation of a new generation of economically socialized engineering and technical specialists, who own a sufficient level of economic competences, that…

  13. Rapid population growth.

    Science.gov (United States)

    1972-01-01

    At the current rate of population growth, world population by 2000 is expected to reach 7 billion or more, with developing countries accounting for some 5.4 billion, and economically advanced nations accounting for 1.6 billion. 'Population explosion' is the result of falling mortality rates and continuing high birth rates. Many European countries, and Japan, have already completed what is termed as demographic transition, that is, birth rates have fallen to below 20 births per 1000 population, death rates to 10/1000 population, and annual growth rates are 1% or less; annual growth rates for less developed countries ranged from 2 to 3.5%. Less developed countries can be divided into 3 groups: 1) countries with both high birth and death rates; 2) countries with high birth rates and low death rates; and 3) countries with intermediate and declining birth rates and low death rates. Rapid population growth has serious economic consequences. It encourages inequities in income distribution; it limits rate of growth of gross national product by holding down level of savings and capital investments; it exerts pressure on agricultural production and land; and it creates unemployment problems. In addition, the quality of education for increasing number of chidren is adversely affected, as high proportions of children reduce the amount that can be spent for the education of each child out of the educational budget; the cost and adequacy of health and welfare services are affected in a similar way. Other serious consequences of rapid population growth are maternal death and illness, and physical and mental retardation of children of very poor families. It is very urgent that over a billion births be prevented in the next 30 years to reduce annual population growth rate from the current 2% to 1% per year.

  14. Rapidly Progressive Disseminated Sporotrichosis as the First Presentation of HIV Infection in a Patient with a Very Low CD4 Cell Count.

    Science.gov (United States)

    de Oliveira-Esteves, Isis Cristine Morávia Ribeiro; Almeida Rosa da Silva, Guilherme; Eyer-Silva, Walter de Araujo; Basílio-de-Oliveira, Rodrigo Panno; de Araujo, Luciana Ferreira; Martins, Carlos José; Neves-Motta, Rogério; Velho Mendes de Azevedo, Marcelo Costa; Signorini, Dario José Hart Pontes; Francisco da Cunha Pinto, Jorge; Moura, Lívia Machado; Laterça, Rafael Jacyntho; Pereira, Diogo Raphael Garcia de Oliveira; do Lago, Isabela Vieira; Raphael de Almeida Ferry, Fernando

    2017-01-01

    Sporotrichosis is a human and animal disease caused by species of the Sporothrix schenckii complex. It is classically acquired through traumatic inoculation of fungal elements. Most frequently, sporotrichosis presents as a fixed cutaneous or as a lymphocutaneous form. A much smaller number of cases occur as cutaneous disseminated and disseminated forms. These cases require immediate diagnosis and management to reduce morbidity and mortality. We present the case of a 34-year-old male patient in whom the first presentation of HIV infection was a rapidly progressive sporotrichosis with multiple cutaneous lesions, a high fungal burden in tissues, and pulmonary involvement. He had an extremely low CD4 cell count (06/mm 3 ). Treatment with amphotericin B deoxycholate led to complete clinical resolution. Sporotrichosis remains a neglected opportunistic infection among HIV-infected patients in Rio de Janeiro state, Brazil, and awareness of this potentially fatal infection is of utmost importance if treatment is not to be delayed and if potentially devastating complications are to be avoided.

  15. ALMR deployment economic analysis

    International Nuclear Information System (INIS)

    Delene, J.G.; Fuller, L.C.; Hudson, C.R.

    1993-06-01

    This analysis seeks to model and evaluate the economics of the use of Advanced Liquid Metal Reactors (ALMR) as a component of this country's future electricity generation mix. The ALMR concept has the ability to utilize as fuel the fissile material contained in previously irradiated nuclear fuel (i.e., spent fuel). While not a requirement for the successful deployment of ALMR power plant technology, the reprocessing of spent fuel from light water reactors (LWR) is necessary for any rapid introduction of ALMR power plants. In addition, the reprocessing of LWR spent fuel may reduce the number of high level waste repositories needed in the future by burning the long-lived actinides produced in the fission process. With this study, the relative economics of a number of potential scenarios related to these issues are evaluated. While not encompassing the full range of all possibilities, the cases reported here provide an indication of the potential costs, timings, and relative economic attractiveness of ALMR deployment

  16. Rapid Population Growth-Cause or Result of Global Problems?

    Science.gov (United States)

    Schwartz, Richard H.

    Explosive population growth is a symptom of the world's unjust and inequitable social, political, and economic conditions. The current rate of growth is staggering, particularly in the cities of the underdeveloped countries. While some progress has been made in slowing population growth, several factors still contribute to its momentum. One of…

  17. The Care Economy, Women's Economic Empowerment, and China's ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Over the past three decades, China's economy has grown rapidly, creating ... of care work on women's labour market outcomes and economic empowerment; ... Socially equitable climate action is essential to strengthen the resilience of all ...

  18. Inclusive growth and development: An IDRC-World Economic Forum ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Advancing economic growth while achieving broad-based progress in living ... It will develop regional and global platforms whereby the private sector, local ... cooperation agreement to support joint research projects in December 2017.

  19. Single wafer rapid thermal multiprocessing

    International Nuclear Information System (INIS)

    Saraswat, K.C.; Moslehi, M.M.; Grossman, D.D.; Wood, S.; Wright, P.; Booth, L.

    1989-01-01

    Future success in microelectronics will demand rapid innovation, rapid product introduction and ability to react to a change in technological and business climate quickly. These technological advances in integrated electronics will require development of flexible manufacturing technology for VLSI systems. However, the current approach of establishing factories for mass manufacturing of chips at a cost of more than 200 million dollars is detrimental to flexible manufacturing. The authors propose concepts of a micro factory which may be characterized by more economical small scale production, higher flexibility to accommodate many products on several processes, and faster turnaround and learning. In-situ multiprocessing equipment where several process steps can be done in sequence may be a key ingredient in this approach. For this environment to be flexible, the equipment must have ability to change processing environment, requiring extensive in-situ measurements and real time control. This paper describes the development of a novel single wafer rapid thermal multiprocessing (RTM) reactor for next generation flexible VLSI manufacturing. This reactor will combine lamp heating, remote microwave plasma and photo processing in a single cold-wall chamber, with applications for multilayer in-situ growth and deposition of dielectrics, semiconductors and metals

  20. Implementing a Progressive Consumption Tax: Advantages of Adopting the VAT Credit-Method System

    OpenAIRE

    Grinberg, Itai

    2006-01-01

    A credit–method value–added tax, a payroll tax, and a business–level wage subsidy can approximate the economic and distributional consequences of a subtraction–method X–tax. Such a credit–method progressive consumption tax has administrative advantages as compared to a subtraction–method progressive consumption tax, once certain political factors are taken into account. Further, unlike a subtraction–method system, a credit–method progressive consumption tax could easily interact with other ta...

  1. Influence Factors of the Economic Development Level Across European Countries

    OpenAIRE

    Diana Ioana POPA

    2016-01-01

    The economic development level of a country refers to the measure of the progress in an economy that could be measured, especially through GDP or GDP per capita. The level of these indicators can be influenced by many factors as a large scale, from social and economical to environmental and government policies factors. The paper aims to investigate some of these influence factors of the economic development level, represented in this case by GDP per capita, across European countries in the...

  2. 77 FR 21081 - Bureau of Economic Analysis Advisory Committee

    Science.gov (United States)

    2012-04-09

    ... new and rapidly growing economic activities arising from innovative and advancing technologies, and... meeting is open to the public. Because of security procedures, anyone planning to attend the meeting must...

  3. 75 FR 49890 - Bureau of Economic Analysis Advisory Committee

    Science.gov (United States)

    2010-08-16

    ... new and rapidly growing economic activities arising from innovative and advancing technologies, and... meeting is open to the public. Because of security procedures, anyone planning to attend the meeting must...

  4. 76 FR 9743 - Bureau of Economic Analysis Advisory Committee

    Science.gov (United States)

    2011-02-22

    ... new and rapidly growing economic activities arising from innovative and advancing technologies, and... meeting is open to the public. Because of security procedures, anyone planning to attend the meeting must...

  5. 78 FR 10599 - Bureau of Economic Analysis Advisory Committee

    Science.gov (United States)

    2013-02-14

    ... new and rapidly growing economic activities arising from innovative and advancing technologies, and... meeting is open to the public. Because of security procedures, anyone planning to attend the meeting must...

  6. 75 FR 8922 - Bureau of Economic Analysis Advisory Committee

    Science.gov (United States)

    2010-02-26

    ... new and rapidly growing economic activities arising from innovative and advancing technologies, and... meeting is open to the public. Because of security procedures, anyone planning to attend the meeting must...

  7. 76 FR 59111 - Bureau of Economic Analysis Advisory Committee

    Science.gov (United States)

    2011-09-23

    ... new and rapidly growing economic activities arising from innovative and advancing technologies, and... meeting is open to the public. Because of security procedures, anyone planning to attend the meeting must...

  8. The Nexus between Artificial Intelligence and Economics

    NARCIS (Netherlands)

    van de Gevel, A.J.W.; Noussair, C.N.

    2012-01-01

    This book is organized as follows. Section 2 introduces the notion of the Singularity, a stage in development in which technological progress and economic growth increase at a near-infinite rate. Section 3 describes what artificial intelligence is and how it has been applied. Section 4 considers

  9. Nondestructive Evaluation Program: Progress in 1986

    International Nuclear Information System (INIS)

    1987-07-01

    The increasing cost of equipment for power generating plants and the potential increases in productivity and safety available through rapidly developing Nondestructive Evaluation (NDE) technology led EPRI to initiate a Nondestructive Evaluation Program in 1974. To date, the major focus has been on light water reactor inspection problems; however, increased application to other systems is now under way. This report presents a comprehensive review of the EPRI effort in the NDE area. Most of the report consists of contractor-supplied progress reports on each current project. An organizational plan of the program is presented in overview. In addition, organization from several viewpoints is presented, e.g., in-service inspection operators, R and D personnel, and utility representatives. The report summarizes significant progress made since the previous EPRI Special Report NP-4315-SR was issued in May 1986. Section 1 contains information about the program organization, and the sections that follow contain contractor-supplied progress reports of each current project. The progress reports are grouped by plant components - pipe, pressure vessel, steam generator and boiler tubes, and turbine. In addition, Part 6 is devoted to discussions of technology transfer

  10. Central Blood Pressure and Chronic Kidney Disease Progression

    Directory of Open Access Journals (Sweden)

    Debbie L. Cohen

    2011-01-01

    Full Text Available Hypertension, diabetes, and proteinuria are well-recognized risk factors for progressive kidney function loss. However, despite excellent antihypertensive and antidiabetic drug therapies, which also often lower urinary protein excretion, there remains a significant reservoir of patients with chronic kidney disease who are at high risk for progression to end-stage kidney disease. This has led to the search for less traditional cardiovascular risk factors that will help stratify patients at risk for more rapid kidney disease progression. Among these are noninvasive estimates of vascular structure and function. Arterial stiffness, manifested by the pulse wave velocity in the aorta, has been established in a number of studies as a significant risk factor for kidney disease progression and cardiovascular endpoints. Much less well studied in chronic kidney disease are measures of central arterial pressures. In this paper we cover the physiology behind the generation of the central pulse wave contour and the studies available using these approaches and conclude with some speculations on the rationale for why measurements of central pressure may be informative for the study of chronic kidney disease progression.

  11. Why higher economic growth cannot always enhance human development

    OpenAIRE

    Ahmed, Md Montasir

    2017-01-01

    This paper studies why higher economic growth cannot always enhance human development. In general, these two dimensions have a strong and positive relationship, but some countries appear unable to balance this relationship. As a consequence, there are some countries with high economic growth but sluggish human development progress. This paper studies how other factors besides GDP – women labor force participation, urbanization, and inequality - are correlated to human development. I construct...

  12. An analysis of social consequences of rapid fertility decline in China.

    Science.gov (United States)

    Liu, Z; Liu, L

    1988-12-01

    Rapid fertility decline in China has brought about 2 direct effects: 1) the natural increase of the population has slowed down, and 2) the age structure has changed from the young to the adult type. These 2 effects have caused a series of economic and social consequences. Rapid fertility decline increases the gross national product per capita and accelerates the improvement of people's lives. Rapid fertility decline slows population growth and speeds up the accumulation of capital and the development of the economy. Since 1981, accumulation growth has exceeded consumption growth. Fertility decline alleviates the enrollment pressure on primary and secondary schools, raises the efficiency of education funds, and promotes the popularization of education. The family planning program strengthens the maternal and child health care and the medical care systems. As the result of economic development, the people's nutritional levels are improving. The physical quality of teenagers has improved steadily. The change in the age structure will alleviate the tension of rapid population growth and benefit population control in the next century. Fertility decline forces the traditional attitude toward childbearing from "more children, more happiness" to improved quality of children. The rapid fertility decline has caused a great deal of concern both inside and outside China about the aging of the population. The labor force, however, will continue to grow for the next 60 years. At present, China's population problems are still those of population growth.

  13. Rapid chemical separations

    CERN Document Server

    Trautmann, N

    1976-01-01

    A survey is given on the progress of fast chemical separation procedures during the last few years. Fast, discontinuous separation techniques are illustrated by a procedure for niobium. The use of such techniques for the chemical characterization of the heaviest known elements is described. Other rapid separation methods from aqueous solutions are summarized. The application of the high speed liquid chromatography to the separation of chemically similar elements is outlined. The use of the gas jet recoil transport method for nuclear reaction products and its combination with a continuous solvent extraction technique and with a thermochromatographic separation is presented. Different separation methods in the gas phase are briefly discussed and the attachment of a thermochromatographic technique to an on-line mass separator is shown. (45 refs).

  14. The Economic Sovereignty of the State as the Defining Instrument of Economic Policy in the Context of Globalization

    Directory of Open Access Journals (Sweden)

    Mykytas Viktoriia V.

    2017-10-01

    Full Text Available The modern world is characterized by rapid integration and globalization processes, which have both a positive and a negative impact on the development of each country. National economies operate in the midst of global uncertainty, which is becoming the platform for the formation and implementation of the State economic policy, which should not only describe the conditions for strategic development of country but also adequately respond to the risks emerging out of the complex integration processes. The failure of the State to respond in a timely and adequate manner to the risks will result in lesser benefits and positive effects of integration processes than the impact of destabilizing factors. In such circumstances, economic sovereignty becomes the most important instrument of the State through which it can defend its national economic interests and form an effective economic policy.

  15. The application of automatic chemiluminescence machine in rapid immune detection

    International Nuclear Information System (INIS)

    Lin Aizhen; Li Xuanwei; Chen Binhong; Li Zhenqian; Chen Zhaoxuan

    2004-01-01

    Objective: To provide high-quality, rapid and dependable result for clinical practice, and give satisfactory service to patients of different economical status by supplementation with other labeling immune examination. With an innovative attitude, we carried out efficient technical reform on ACS180 automatic chemiluminescence machine, making it possible for patients to complete the whole process including examination, check-out, diagnosis and getting drugs. The reported will be issued within an hour, thus a rapid immune detection service was established in out-patients department. Methods: 1. ACS-180 automatic chemiluminescence machine is used based on the principle of chemiluminescence immune methods. 2. The reagents are provided by Ciba-Comig Company of USA, composed of anti acridinium ester antibody of liquid phase and particulate antigen of solid phase wrapped in magnetic powder. 3. Calibration and quality control: high and low concentration are set for each calibration fluid with attached standard curve. Product for quality controlling includes three concentration of low, moderate and high. Results: 1. rapid machine detection for sample: serum is replaced with plasma coagulated by heparin, and comparison among series of methods using serum or plasma suggest no significant difference exists. 2. The problem about fasting detection: chemiluminescence machine measure optical density directly, with the results hardly being influenced by turbidity. But attention should be paid to the treatment of lipid turbid samples. 3. Other innovations: (1) direct placement of sample tube on machine: a cushion is placed on sample plate to transfer sample to machine directly after centrifugation, saving time and reducing the accident in sample transference. (2) for HCG quantification in blood and urine, 'gold criteria' is used firstly in screening to determine approximately the dilution range, with an advantage of saving time and reagent as well as accuracy. (3) we design a

  16. Research Progress on Furfural Residues Recycling : A Literature Review

    NARCIS (Netherlands)

    Dai, Chun'ai; Liu, Bo; Girisuta, B.; Heeres, H.J.

    2010-01-01

    Millions of tons of furfural residues from the furfural industry are produced every year in China. Proper recycling of these residues is highly desirable as it may reduce associated environmental problems and increase the economic viability of the furfural industry. Research progress on furfural

  17. ALS patients' regulatory T lymphocytes are dysfunctional, and correlate with disease progression rate and severity.

    Science.gov (United States)

    Beers, David R; Zhao, Weihua; Wang, Jinghong; Zhang, Xiujun; Wen, Shixiang; Neal, Dan; Thonhoff, Jason R; Alsuliman, Abdullah S; Shpall, Elizabeth J; Rezvani, Katy; Appel, Stanley H

    2017-03-09

    Neuroinflammation is a pathological hallmark of ALS in both transgenic rodent models and patients, and is characterized by proinflammatory T lymphocytes and activated macrophages/microglia. In ALS mouse models, decreased regulatory T lymphocytes (Tregs) exacerbate the neuroinflammatory process, leading to accelerated motoneuron death and shortened survival; passive transfer of Tregs suppresses the neuroinflammation and prolongs survival. Treg numbers and FOXP3 expression are also decreased in rapidly progressing ALS patients. A key question is whether the marked neuroinflammation in ALS can be attributed to the impaired suppressive function of ALS Tregs in addition to their decreased numbers. To address this question, T lymphocyte proliferation assays were performed. Compared with control Tregs, ALS Tregs were less effective in suppressing responder T lymphocyte proliferation. Although both slowly and rapidly progressing ALS patients had dysfunctional Tregs, the greater the clinically assessed disease burden or the more rapidly progressing the patient, the greater the Treg dysfunction. Epigenetically, the percentage methylation of the Treg-specific demethylated region was greater in ALS Tregs. After in vitro expansion, ALS Tregs regained suppressive abilities to the levels of control Tregs, suggesting that autologous passive transfer of expanded Tregs might offer a novel cellular therapy to slow disease progression.

  18. ALS patients’ regulatory T lymphocytes are dysfunctional, and correlate with disease progression rate and severity

    Science.gov (United States)

    Beers, David R.; Zhao, Weihua; Wang, Jinghong; Zhang, Xiujun; Wen, Shixiang; Neal, Dan; Thonhoff, Jason R.; Alsuliman, Abdullah S.; Shpall, Elizabeth J.; Rezvani, Katy

    2017-01-01

    Neuroinflammation is a pathological hallmark of ALS in both transgenic rodent models and patients, and is characterized by proinflammatory T lymphocytes and activated macrophages/microglia. In ALS mouse models, decreased regulatory T lymphocytes (Tregs) exacerbate the neuroinflammatory process, leading to accelerated motoneuron death and shortened survival; passive transfer of Tregs suppresses the neuroinflammation and prolongs survival. Treg numbers and FOXP3 expression are also decreased in rapidly progressing ALS patients. A key question is whether the marked neuroinflammation in ALS can be attributed to the impaired suppressive function of ALS Tregs in addition to their decreased numbers. To address this question, T lymphocyte proliferation assays were performed. Compared with control Tregs, ALS Tregs were less effective in suppressing responder T lymphocyte proliferation. Although both slowly and rapidly progressing ALS patients had dysfunctional Tregs, the greater the clinically assessed disease burden or the more rapidly progressing the patient, the greater the Treg dysfunction. Epigenetically, the percentage methylation of the Treg-specific demethylated region was greater in ALS Tregs. After in vitro expansion, ALS Tregs regained suppressive abilities to the levels of control Tregs, suggesting that autologous passive transfer of expanded Tregs might offer a novel cellular therapy to slow disease progression. PMID:28289705

  19. Industrial policy, production efficiency improvement and the Chinese county economic growth

    Directory of Open Access Journals (Sweden)

    Wang Zhenhua

    2016-12-01

    Full Text Available This study aims at analyzing the difference in the level of economic development between China’s counties from the two perspectives of industrial policy and production efficiency. Based on panel data of 1830 Chinese counties, this study employs the new classical economic growth theory framework to analyze the counties’ economic growth by the perpetual inventory method, Malmquist index, among others. The results show that the economy of the counties exhibits δ convergence since 2004, and the absolute differences in the different counties are expanding. Industrial policy ensures the additional deepening of the level of capital in the county. Additionally, a substantial difference was observed between the agricultural sector and the non-agricultural sector, whereby the total factor productivity and the technical efficiency are on the rise, resulting in the phenomenon of dual paths of technological progress. In summary, the capital deepening difference between the sectors, production efficiency, and dual paths of technological progress owing to the counties’ industrial policy are the basic reasons for the regional differences in the level of economic development in China.

  20. Obesity and cardiovascular disease in developing countries: a growing problem and an economic threat.

    Science.gov (United States)

    Raymond, Susan U; Leeder, Stephen; Greenberg, Henry M

    2006-03-01

    This review examines the rise of risk factors for cardiovascular disease, especially obesity, in developing countries and the implications for both health and economics. In the majority of developing countries fertility and infant and child mortality have fallen markedly, and life expectancies have increased. Rapid urbanization, falling food prices, and globalization of economies have contributed to an increase in risk factors for chronic disease. Recent work indicates that the prevalence of these risk factors, including obesity, is rising faster than the historical experience of the West. The transition is affecting women in particular, and increases in risk factors are more marked among lower incomes in growing economies than among the wealthy. Rather than the stereotypical problem of the rich, chronic disease is now a problem for the poor. Significant research in this area of global health has only been undertaken in the last decade. Additional field research is needed in every dimension of the transition, both to document the problem itself and to determine its economic and societal impact and cost effective responses. Two critical factors are virtually absent from existing work and should be emphasized. First, the impact of rising risk factors for, and mortality from, cardiovascular disease in the work force may imply a growing threat to continued economic progress. Second, because risk factor reduction requires society-wide strategies, broad public-private coalitions will be needed to mobilize sectors beyond healthcare.

  1. [The population and economic problems of South Asia].

    Science.gov (United States)

    Gu, J

    1983-07-29

    South Asia, which includes Central South Asia, Southeast Asia, and Southwest Asia, had a comparatively higher population growth rate during the 30-year postwar period because of the overall backward economy and strong religious tradition. From the viewpoint of economics, the high population growth in South Asia has slowed down economic growth, increased the foreign trade imblance, and worsened poverty. Secondly, the rapid population growth has overburdened the area's educational system. The illiteracy rate has been going up continuously because of inadequate funds available for education. Thirdly, young labor is lacking in skills, training, and work experience, and related productivity has declined. Consequently, profits, the investment capability, and wages are also declining. The problems of the oversupply of labor, unemployment, and poverty have also become increasingly serious. In addition, the rapid population growth has intensified the pressure on the food supply and worsened the average nutrition of the general public. In recent years, countries in South Asia have been trying to deal with various problems caused by the rapid population growth. Measures have been taken to control the population growth, with a redistribution of the population to places outside cities, and export labor to oil-producing nations of the Middle East and Africa in order to solve the problem of the domestic labor surplus and earn more income for the foreign exchange. Countries in South Asia need more time and effort to achieve a balance between the population growth and economic development.

  2. Development of inactivated poliovirus vaccine from Sabin strains: A progress report.

    Science.gov (United States)

    Okayasu, Hiromasa; Sein, Carolyn; Hamidi, Ahd; Bakker, Wilfried A M; Sutter, Roland W

    2016-11-01

    The Global Polio Eradication Initiative (GPEI) has seen significant progress since it began in 1988, largely due to the worldwide use of oral poliovirus vaccine (OPV). In order to achieve polio eradication the global cessation of OPV is necessary because OPV contains live attenuated poliovirus, which in rare circumstances could re-gain wild poliovirus (WPV) characteristics with potential to establish transmission. The GPEI endgame strategy for the period 2013-2018 recommends the globally synchronised sequential cessation of the Sabin strains contained in the OPV, starting with type 2 Sabin. The withdrawal of Sabin type 2 took place in April 2016, with the introduction of at least one dose of inactivated poliovirus vaccine (IPV) as a risk mitigation strategy. The introduction of IPV into 126 countries since 2013 has required a rapid scale-up of IPV production by the two manufacturers supplying the global public sector market. This scale-up has been fraught with challenges, resulting in reductions of 40-50% of initial supply commitments. Consequently, 22 countries will not be supplied until 2018, and another 23 countries will experience serious stock-outs. In the last decade repeated calls-for-action were made to the global community to invigorate their vision and investment in developing "new poliovirus vaccines" including the development of IPV from less-virulent strains, such as Sabin-IPV (S-IPV). The conventional Salk-IPV production is limited to high-income industrialized-country manufacturers due to the containment requirements (i.e., high sanitation, low force-of-poliovirus-infection, and high population immunity). The use of Sabin strains in the production of S-IPV carries a lower biosafety risk, and was determined to be suitable for production in developing countries, expanding the manufacturing base and making IPV more affordable and accessible in the long term. Significant progress in the S-IPV has been made since 2006. S-IPV is now licensed as S-IPV in

  3. The development of capability measures in health economics: opportunities, challenges and progress.

    Science.gov (United States)

    Coast, Joanna; Kinghorn, Philip; Mitchell, Paul

    2015-04-01

    Recent years have seen increased engagement amongst health economists with the capability approach developed by Amartya Sen and others. This paper focuses on the capability approach in relation to the evaluative space used for analysis within health economics. It considers the opportunities that the capability approach offers in extending this space, but also the methodological challenges associated with moving from the theoretical concepts to practical empirical applications. The paper then examines three 'families' of measures, Oxford Capability instruments (OxCap), Adult Social Care Outcome Toolkit (ASCOT) and ICEpop CAPability (ICECAP), in terms of the methodological choices made in each case. The paper concludes by discussing some of the broader issues involved in making use of the capability approach in health economics. It also suggests that continued exploration of the impact of different methodological choices will be important in moving forward.

  4. 77 FR 60965 - Bureau of Economic Analysis Advisory Committee

    Science.gov (United States)

    2012-10-05

    ..., especially in areas of new and rapidly growing economic activities arising from innovative and advancing... meeting is open to the public. Because of security procedures, anyone planning to attend the meeting must...

  5. Determinants of Human Capital Formation and Economic Growth of African Countries

    Science.gov (United States)

    Oketch, Moses O.

    2006-01-01

    Rapid economic growth and improving living standards have benefited almost all regions of the world since the industrial revolution. Africa stands out as one regional exception. While several factors such as civil wars and rampant corruption have been associated with poor economic performance of the African region in the international community,…

  6. "60x30TX" 2017 Progress Report

    Science.gov (United States)

    Texas Higher Education Coordinating Board, 2017

    2017-01-01

    Central to the goals of "60x30TX" is maintaining Texas as a global economic player by having an educated population, making them aware of their marketable skills, and helping them manage their student loan debt. If the 2016 progress report for "60x30TX" was about getting out the word, this report is about expanding that reach…

  7. Expanding economic opportunities for women and youth in Africa ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The celebration of “rising Africa” — strong economic growth and progress in health ... will be guided by careful consideration of geographic diversity, data availability, ... IWRA/IDRC webinar on climate change and adaptive water management.

  8. Analyzing socio-economic impacts of tourism : Case of Lumbini region- Nepal

    OpenAIRE

    K.C., Shambhu; Gewali, Jhabindra

    2014-01-01

    The first objective of this Thesis is to identify, select, and analyze the socio- economic impacts of faith tourism in Lumbini region. The second objective is to present the impacts in context of changing business environment. And the last objective is to develop strategies for economic progress in a society. In this research work previous reports, theses, literatures and reviews were studied to get an idea about the socio-economic impacts of faith tourism in Lumbini region. In addition,...

  9. The economic impact of NASA R and D spending: Executive summary

    Science.gov (United States)

    Evans, M. K.

    1976-01-01

    An evaluation of the economic impact of NASA research and development programs is made. The methodology and the results revolve around the interrelationships existing between the demand and supply effects of increased research and development spending, in particular, NASA research and development spending. The INFORUM Inter-Industry Forecasing Model is used to measure the short-run economic impact of alternative levels of NASA expenditures for 1975. An aggregate production function approach is used to develop the data series necessary to measure the impact of NASA research and development spending, and other determinants of technological progress, on the rate of growth in productivity of the U. S. economy. The measured relationship between NASA research and development spending and technological progress is simulated in the Chase Macroeconometric Model to measure the immediate, intermediate, and long-run economic impact of increased NASA research and development spending over a sustained period.

  10. Health inequalities during 20 years of rapid economic development in China (1980-2000): a mortality analysis.

    Science.gov (United States)

    Zheng, XiaoYing; Song, XinMing; Chen, Gong; You, YunZhong; Ren, Qiang; Liu, JuFen; Zhang, Lei; Tan, LingFang; Wei, JiHong; Chen, QiuYuan

    2011-08-01

    To examine the influence of China's economic reforms on population health and regional mortality rates. Longitudinal study measuring the mortality trends and their regional variations. Using data from the three most recent national censuses, we used the model life table to adjust the mortality levels within the population for each census, and to calculate life expectancy. We then examined the variation in patterns of mortality and population health by economic status, region and gender from 1980-2000. Life expectancy varied with economic status, province, and gender. Results showed that, although life expectancy in China had increased overall since the early 1980s, regional differences became more pronounced. Life expectancy for populations who live in the eastern coastal provinces are greater than those in the western regions. Differences in life expectancy are primarily related to differences in regional economic development, which in turn exacerbate regional health inequalities. Therefore, it is necessary to improve economic development in less developed regions and to improve health policies and the public health system that address the needs of everyone. Copyright © 2011 The Editorial Board of Biomedical and Environmental Sciences. Published by Elsevier B.V. All rights reserved.

  11. The Republic of Yemen - Economic Growth : Sources, Constraints and Potentials

    OpenAIRE

    World Bank

    2002-01-01

    High and sustained rate of economic growth in Yemen is a necesary, though not sufficient, condition for reduction of the high incidence of poverty and for raising the living standards of Yemeni citizens. Evidence in this report suggests that the main obstacle to rapid and sustained economic growth is the weak governance that characterizes Yemen in addition to the weaknesses in domestic sec...

  12. The Political Economy of Postwar Economic Development in Sri Lanka

    Directory of Open Access Journals (Sweden)

    Prasanna-Perera Welgamage Lalith Prasanna-Perera

    2014-12-01

    Full Text Available Thirty years of civil war in Sri Lanka has affected economic, political, social, cultural and psychological aspects of the society significantly. This paper presents an overview of postwar development strategies in Sri Lanka and compares it with the prewar economy from a political economic perspective. The paper specifically examines the progress of the overall postwar development in the war affected Northern Province of Sri Lanka. Using mixed methodologies data was gathered on critical aspects related to political economy. According to the current study, no clear progress has been made in the areas of economic growth, FDI growth, household income, and poverty and income inequality in the postwar economy of Sri Lanka when compared with the prewar economy. Government fiscal policy targets the postwar reconstruction works while monetary policy enjoys the amalgamation of North and East provinces to country’s aggregate supply apart from introducing very few loan schemes. Security phobia of the government of Sri Lanka limits local, national, regional and international none-government organizations especially in the North and East. There is a considerable amount of progress made in the area of infrastructure development and resettlement of displaced persons. However, primary data from the study indicates these strategies lack conflict sensitivity and public trust. This study emphasizes that postwar economic development strategies should address the critical determinants of sustainable recovery, peace and development aiming at protecting human rights, ensuring rule of law, establishing efficient public service system and finally offering constitutional reforms in Sri Lanka.

  13. Social influences on risk attitudes : Applications in economics

    NARCIS (Netherlands)

    Trautmann, S.T.; Vieider, F.M.; Roeser, S.; Hillerbrand, R.; Sandin, P.; Peterson, M.

    2012-01-01

    Economic research on risk attitudes has traditionally focused on individual decision-making issues, without any consideration for potential social influences on preferences. This has been changing rapidly over the last years, with economists often taking inspiration from earlier psychological

  14. Progress in research on Tourette syndrome

    Science.gov (United States)

    Black, Kevin J.; Jankovic, Joseph; Hershey, Tamara; McNaught, Kevin St. P.; Mink, Jonathan W.; Walkup, John

    2014-01-01

    Tourette syndrome (TS) is a heritable neuropsychiatric disorder commonly complicated by obsessions and compulsions, but defined by frequent unwanted movements (motor tics) and vocalizations (phonic tics) that develop in childhood or adolescence. In recent years, research on TS has progressed rapidly on several fronts. Inspired by the Fifth International Scientific Symposium on Tourette Syndrome, the articles in this special issue review advances in the phenomenology, epidemiology, genetics, pathophysiology, and treatment of TS. PMID:25436182

  15. Progress in molecular precursors for electronic materials

    Energy Technology Data Exchange (ETDEWEB)

    Buhro, W.E. [Washington Univ., St. Louis, MO (United States)

    1996-09-01

    Molecular-precursor chemistry provides an essential underpinning to all electronic-materials technologies, including photovoltaics and related areas of direct interest to the DOE. Materials synthesis and processing is a rapidly developing field in which advances in molecular precursors are playing a major role. This article surveys selected recent research examples that define the exciting current directions in molecular-precursor science. These directions include growth of increasingly complex structures and stoichiometries, surface-selective growth, kinetic growth of metastable materials, growth of size-controlled quantum dots and quantum-dot arrays, and growth at progressively lower temperatures. Continued progress in molecular-precursor chemistry will afford precise control over the crystal structures, nanostructures, and microstructures of electronic materials.

  16. [Employment and education in the 2nd economic and social development plan of Togo].

    Science.gov (United States)

    Dovi-sodemekou, F B

    1985-01-01

    Togo is a developing country whose population is increasing at the rapid rate of 2.7%/year. Economic development is therefore a necessity to ensure at least an average standard of living. Plans of development include objectives of structural societal changes, including improvements in education and employment. This study analyzes the evolution of population activities. It identifies obstacles to the improvement of education and employment. The investigation examines the employment and education situation before adoption of the 2nd plan of Togo and predicts the probable evolution of the situation. Despite the priority accorded to agriculture, the 2nd plan appears to give greater importance to industry. The industrial and commercial sector has witnessed a 65.2% investment increase, whereas the rural sector had an investment increase of 11.8%. The 2nd plan, in view of its relation to the evolution of economic activities, took into account the demand for manual labor. In the private sector, industries should occupy an important position. The dualism of a modern and a traditional sector is considered a cause of underdevelopment. The modern sector should be developed in order to suppress the traditional sector and allow progress in society. As a result of this approach, agriculture is given a 2ndary role.

  17. The economics of offshore wind

    International Nuclear Information System (INIS)

    Green, Richard; Vasilakos, Nicholas

    2011-01-01

    This paper presents an overview of the main issues associated with the economics of offshore wind. Investment in offshore wind systems has been growing rapidly throughout Europe, and the technology will be essential in meeting EU targets for renewable energy in 2020. Offshore wind suffers from high installation and connection costs, however, making government support essential. We review various support policies used in Europe, concluding that tender-based feed-in tariff schemes, as used in Denmark, may be best for providing adequate support while minimising developers' rents. It may prove economic to build an international offshore grid connecting wind farms belonging to different countries that are sited close to each other. (author)

  18. The economics of offshore wind

    Energy Technology Data Exchange (ETDEWEB)

    Green, Richard; Vasilakos, Nicholas [Department of Economics, University of Birmingham, Birmingham B15 2TT (United Kingdom)

    2011-02-15

    This paper presents an overview of the main issues associated with the economics of offshore wind. Investment in offshore wind systems has been growing rapidly throughout Europe, and the technology will be essential in meeting EU targets for renewable energy in 2020. Offshore wind suffers from high installation and connection costs, however, making government support essential. We review various support policies used in Europe, concluding that tender-based feed-in tariff schemes, as used in Denmark, may be best for providing adequate support while minimising developers' rents. It may prove economic to build an international offshore grid connecting wind farms belonging to different countries that are sited close to each other. (author)

  19. The potential for modification in cloning and vitrification technology to enhance genetic progress in beef cattle in Northern Australia.

    Science.gov (United States)

    Taylor-Robinson, Andrew W; Walton, Simon; Swain, David L; Walsh, Kerry B; Vajta, Gábor

    2014-08-01

    Recent advances in embryology and related research offer considerable possibilities to accelerate genetic improvement in cattle breeding. Such progress includes optimization and standardization of laboratory embryo production (in vitro fertilization - IVF), introduction of a highly efficient method for cryopreservation (vitrification), and dramatic improvement in the efficiency of somatic cell nuclear transfer (cloning) in terms of required effort, cost, and overall outcome. Handmade cloning (HMC), a simplified version of somatic cell nuclear transfer, offers the potential for relatively easy and low-cost production of clones. A potentially modified method of vitrification used at a centrally located laboratory facility could result in cloned offspring that are economically competitive with elite animals produced by more traditional means. Apart from routine legal and intellectual property issues, the main obstacle that hampers rapid uptake of these technologies by the beef cattle industry is a lack of confidence from scientific and commercial sources. Once stakeholder support is increased, the combined application of these methods makes a rapid advance toward desirable traits (rapid growth, high-quality beef, optimized reproductive performance) a realistic goal. The potential impact of these technologies on genetic advancement in beef cattle herds in which improvement of stock is sought, such as in northern Australia, is hard to overestimate. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  20. Model-based economic evaluation in Alzheimer's disease: a review of the methods available to model Alzheimer's disease progression.

    Science.gov (United States)

    Green, Colin; Shearer, James; Ritchie, Craig W; Zajicek, John P

    2011-01-01

    To consider the methods available to model Alzheimer's disease (AD) progression over time to inform on the structure and development of model-based evaluations, and the future direction of modelling methods in AD. A systematic search of the health care literature was undertaken to identify methods to model disease progression in AD. Modelling methods are presented in a descriptive review. The literature search identified 42 studies presenting methods or applications of methods to model AD progression over time. The review identified 10 general modelling frameworks available to empirically model the progression of AD as part of a model-based evaluation. Seven of these general models are statistical models predicting progression of AD using a measure of cognitive function. The main concerns with models are on model structure, around the limited characterization of disease progression, and on the use of a limited number of health states to capture events related to disease progression over time. None of the available models have been able to present a comprehensive model of the natural history of AD. Although helpful, there are serious limitations in the methods available to model progression of AD over time. Advances are needed to better model the progression of AD and the effects of the disease on peoples' lives. Recent evidence supports the need for a multivariable approach to the modelling of AD progression, and indicates that a latent variable analytic approach to characterising AD progression is a promising avenue for advances in the statistical development of modelling methods. Copyright © 2011 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  1. Economic Values and Resource Use

    Directory of Open Access Journals (Sweden)

    Jan Mikael Malmaeus

    2016-05-01

    Full Text Available Absolute decoupling of GDP growth from resource use implies that economic output can be increased without simultaneously increasing input. The essential meaning of this proposition is that the economic values that represent the GDP can be realized by increasing resource efficiency. Given that the GDP is first and foremost a measure of economic activity rather than welfare the possibility of absolute decoupling is theoretically limited. This paper demonstrates theoretically and empirically that economic values at the macroeconomic level are fundamentally determined by the use of production factors, primarily labor and physical capital. Technical innovations or efficiency gains increasing utility without raising the costs of production do not add to the GDP unless they stimulate investments in physical capital. Hence the neoclassical notion of productivity is only found to be relevant as a microeconomic concept. In practice, GDP growth is mostly explained by capital accumulation and a key question is whether or not capital accumulation can be decoupled from the use of materials and energy. This will determine the possibility of decoupling of GDP growth from resource use and environmental impact. Alternative measures of progress focusing on welfare rather than economic activity are more likely to achieve absolute decoupling.

  2. Around the laboratories: Dubna: Physics results and progress on bubble chamber techniques; Stanford (SLAC): Operation of a very rapid cycling bubble chamber; Daresbury: Photographs of visitors to the Laboratory; Argonne: Charge exchange injection tests into the ZGS in preparation for a proposed Booster

    CERN Multimedia

    1969-01-01

    Around the laboratories: Dubna: Physics results and progress on bubble chamber techniques; Stanford (SLAC): Operation of a very rapid cycling bubble chamber; Daresbury: Photographs of visitors to the Laboratory; Argonne: Charge exchange injection tests into the ZGS in preparation for a proposed Booster

  3. Economics as if the earth really mattered. Putting balance back on the balance sheet.

    Science.gov (United States)

    Sherman, D

    1991-09-01

    Some of the thinking in the economic realm which affects the relationship between the economy and the environment is discussed. The standard economic model inherently conflicts with the environment. Humans as consumers have their needs met by maximizing production and efficiency in a free market economy, where an invisible hand guides to profit. The question is raised as to what the environmental impact is for economic growth. The need for clean air, water, and preservation of other living things is not met. It is argued that pollution is a necessary byproduct of production. Economic progress as measured by gross national product (GNP) cannot account for the degradation of nature, e.g., the Alaskan oil spill actually increased GNP. Traditional economics also tell little about the maldistribution of wealth. It is pointed out that Americans spend $5 billion a year on special diets while 400 million around the world are undernourished. Limits to natural resources are also not accounted for by economic theorists, or the value of the seemingly free life-sustaining services performed by a forest in purifying air, preventing erosion and flooding, regulating climate, and supporting biological diversity. It is pointed out that restructuring must occur if the capacity of the Earth to support life is classed in economic terms as an externality. Steady state economic models consider the cycles of production and consumption in the context of the surrounding ecosystem of waste and raw materials and try to achieve a state of equilibrium. Despite the 1972 President's Commission on Population Growth and the American Future's statement that population growth is not necessary for a vital economy, the mythology exists that the economy will collapse, personal income will drop, and business will decline without an ever-growing population. A summary on positive outcomes of zero population growth is given. The economist Julian Simon promotes the view that there is no environmental

  4. Market design for rapid demand response

    DEFF Research Database (Denmark)

    Nielsen, Kurt; Tamirat, Tseganesh Wubale

    We suggest a market design for rapid demand response in electricity markets. The solution consists of remotely controlled switches, meters, forecasting models as well as a flexible auction market to set prices and select endusers job by job. The auction market motivates truth-telling and makes...... it simple to involve the endusers in advance and to activate demand response immediately. The collective solution is analyzed and economic simulations are conducted for the case of Kenya. Kenya has been su ering from unreliable electricity supply for many years and companies and households have learned...... to adjust by investments in backup generators. We focus on turning the many private backup generators into a demand response system. The economic simulation focuses on possible distortion introduced by various ways of splitting the generated surplus from the demand response system. An auction run instantly...

  5. Economic reasoning and artificial intelligence.

    Science.gov (United States)

    Parkes, David C; Wellman, Michael P

    2015-07-17

    The field of artificial intelligence (AI) strives to build rational agents capable of perceiving the world around them and taking actions to advance specified goals. Put another way, AI researchers aim to construct a synthetic homo economicus, the mythical perfectly rational agent of neoclassical economics. We review progress toward creating this new species of machine, machina economicus, and discuss some challenges in designing AIs that can reason effectively in economic contexts. Supposing that AI succeeds in this quest, or at least comes close enough that it is useful to think about AIs in rationalistic terms, we ask how to design the rules of interaction in multi-agent systems that come to represent an economy of AIs. Theories of normative design from economics may prove more relevant for artificial agents than human agents, with AIs that better respect idealized assumptions of rationality than people, interacting through novel rules and incentive systems quite distinct from those tailored for people. Copyright © 2015, American Association for the Advancement of Science.

  6. Yugoslavia's Economic Crisis: the Price of Overexpansion

    NARCIS (Netherlands)

    W. Burger (Willem)

    1984-01-01

    textabstractYugoslavia is one of the rapidly industrialising countries which has had a record of very high rates of economic growth over the past decades and which is now balancing on the brink of bankruptcy. That its grave financial problems have not attracted as much international attention as

  7. Rapid Spontaneously Resolving Acute Subdural Hematoma

    Science.gov (United States)

    Gan, Qi; Zhao, Hexiang; Zhang, Hanmei; You, Chao

    2017-01-01

    Introduction: This study reports a rare patient of a rapid spontaneously resolving acute subdural hematoma. In addition, an analysis of potential clues for the phenomenon is presented with a review of the literature. Patient Presentation: A 1-year-and-2-month-old boy fell from a height of approximately 2 m. The patient was in a superficial coma with a Glasgow Coma Scale of 8 when he was transferred to the authors’ hospital. Computed tomography revealed the presence of an acute subdural hematoma with a midline shift beyond 1 cm. His guardians refused invasive interventions and chose conservative treatment. Repeat imaging after 15 hours showed the evident resolution of the hematoma and midline reversion. Progressive magnetic resonance imaging demonstrated the complete resolution of the hematoma, without redistribution to a remote site. Conclusions: Even though this phenomenon has a low incidence, the probability of a rapid spontaneously resolving acute subdural hematoma should be considered when patients present with the following characteristics: children or elderly individuals suffering from mild to moderate head trauma; stable or rapidly recovered consciousness; and simple acute subdural hematoma with a moderate thickness and a particularly low-density band in computed tomography scans. PMID:28468224

  8. Productivity costs in economic evaluations: past, present, future.

    Science.gov (United States)

    Krol, Marieke; Brouwer, Werner; Rutten, Frans

    2013-07-01

    Productivity costs occur when the productivity of individuals is affected by illness, treatment, disability or premature death. The objective of this paper was to review past and current developments related to the inclusion, identification, measurement and valuation of productivity costs in economic evaluations. The main debates in the theory and practice of economic evaluations of health technologies described in this review have centred on the questions of whether and how to include productivity costs, especially productivity costs related to paid work. The past few decades have seen important progress in this area. There are important sources of productivity costs other than absenteeism (e.g. presenteeism and multiplier effects in co-workers), but their exact influence on costs remains unclear. Different measurement instruments have been developed over the years, but which instrument provides the most accurate estimates has not been established. Several valuation approaches have been proposed. While empirical research suggests that productivity costs are best included in the cost side of the cost-effectiveness ratio, the jury is still out regarding whether the human capital approach or the friction cost approach is the most appropriate valuation method to do so. Despite the progress and the substantial amount of scientific research, a consensus has not been reached on either the inclusion of productivity costs in economic evaluations or the methods used to produce productivity cost estimates. Such a lack of consensus has likely contributed to ignoring productivity costs in actual economic evaluations and is reflected in variations in national health economic guidelines. Further research is needed to lessen the controversy regarding the estimation of health-related productivity costs. More standardization would increase the comparability and credibility of economic evaluations taking a societal perspective.

  9. Planificarea economică sub monarhia autoritară din România (The economic planning under authoritarian monarchy of Romania

    Directory of Open Access Journals (Sweden)

    Florin GRECU

    2016-06-01

    Full Text Available The article analyzes the economic planning institution under authoritarian monarchy of Romania, 1938-1940. The Superior Economic Council, populated by specialists, had the main responsibilities of planning and economic control. The Superior Economic Council composition will be found in the structures of the National Renaissance Front as well as in the composition of the corporatist Parliament. The appointment of the Members of the The Superior Economic Council by royal decree has highlighted the monarch’s desire to have a personal institution, which would be composed of all the important representatives of the Economy, Industry and Finances. The Super Ministry, Ministry of National Economy, headed by Mitiţă Constantinescu, have the task of guidance, coordination and encouragement of the progress for the productive forces distribution of production, direction and supervision of importation, and preparation of economic laws. By the Decree of October 1939, the Ministry of National Economy may could decide the syndicalization of all enterprises, from a specific industrial branch, setting concrete tasks of production and selling of goods. The Superior Economic Council was established to coordinate the corporate economy through policies of planism and economic nationalization, but the corporate institutution of the Romanian authoritative state was the guild

  10. APPLING REMOTE SENSING TECHNIQUE TO MONITORING SPATIAL EXPANSION OF IMPORTANT CITIES IN CHINA-INDOCHINA PENINSULA ECONOMIC CORRIDOR

    Directory of Open Access Journals (Sweden)

    J. Li

    2017-09-01

    Full Text Available Since twentieth Century, the process of economic globalization has made great progress, and Southeast Asia has developed rapidly under the background of international industrial transferring. In this paper, the 6 important nodes cities in China - Indochina Peninsula along the economic corridor are took as study area. The main data is time series Landsat data. The method of object-oriented random forest classification was used to extract the classification results of study area from 2000 to 2015. The urban expansion of the node cities was evaluated by calculating the expansion speed of the impervious surface and the landscape pattern metrics. The results indicated that the method of object oriented random forest classification can effectively extract the urban impervious surface. the overall accuracy is over 81 %, and the Kappa coefficient is over 0.82. In the past 15 years, the expansion speed of Vientiane city was fastest in 6 countries. The area of urban impervious surface expanded 8 times than that of 2000.The pattern of expansion is summarized as “gather first-diffuse then”, “diffuse first-gather then” and “gather”. Overall, the process of urbanization of these cities are still in the rising period.

  11. 78 FR 59648 - Bureau of Economic Analysis Advisory Committee Meeting

    Science.gov (United States)

    2013-09-27

    ... new and rapidly growing economic activities arising from innovative and advancing technologies, and... meeting is open to the public. Because of security procedures, anyone planning to attend the meeting must...

  12. Conflict Between Economic Growth and Environmental Protection

    Energy Technology Data Exchange (ETDEWEB)

    Czech, Bryan

    2012-01-09

    The conflict between economic growth and environmental protection may not be reconciled via technological progress. The fundamentality of the conflict ultimately boils down to laws of thermodynamics. Physicists and other scholars from the physical sciences are urgently needed for helping the public and policy makers grasp the conflict between growth and environmental protection.

  13. Rapid Economic Growth and Natural Gas Consumption Nexus: Looking forward from Perspective of 11th Malaysian Plan

    Science.gov (United States)

    Bekhet, H. A.; Yasmin, T.

    2016-03-01

    The present study investigates the relationship between economic growth and energy consumption by incorporating CO2 emissions, natural gas consumption and population in Malaysia. Annual data and F-bound test and granger causality have applied to test the existence of long run relationship between the series. The results show that variables are cointegrated for long run relationship. The results also indicate that natural gas consumption is an important contributing factor to energy demand and hence economic growth in case of Malaysia. The causality analysis highlights that the feedback hypothesis exists between economic growth and energy consumption. While, conservative hypothesis is validated between natural gas consumption and economic growth which implies that economic growth will push natural gas consumption policies in future. This study opens up new direction for policy makers to formulate a comprehensive natural gas policy to sustain environment for long span of time in case to achieve 11th MP targets.

  14. Social and environmental determinants of child health in Mongolia across years of rapid economic growth: 2000-2010.

    Science.gov (United States)

    Joshi, Nehal; Bolorhon, Bolormaa; Narula, Indermohan; Zhu, Shihua; Manaseki-Hollan, Semira

    2017-10-30

    To understand the effect of economic growth on health, we investigated the trend in socio-economic and regional determinants of child health in Mongolia. This Central Asian country had the fastest economic growth amongst low and middle-income countries (LMICs) from 2000 to 2010 and a healthcare system in transition. Data was from Mongolian multiple indicator cluster surveys (MICS) in 2000, 2005 and 2010. Child nutrition/growth was measured by height-for-age z-score (HAZ), weight-for-age z-score (WAZ), prevalence of stunted (HAZ economic and environmental health determinants on each outcome in each year; 2000, 2005 and 2010. T-tests were used to measure significant change in HAZ and WAZ over the decade. Overall, from 2000 to 2010, there was a significant improvement (p economic factors increased on both stunting and weight. In 2000, region was a significant determinant: children living in three provinces were significantly more likely to be stunted and less likely to be immunised than Ulaanbaatar, but this was not significant by 2010. By 2010, none of the factors were significant determinants of immunisation in children. In 2000, economic status had no effect on stunting (OR = 0.91; 95%CI:0.49,1.66), however by 2010, children in the poorest economic quintile were 4 times more likely to be stunted than the richest (OR = 0.24; 95% CI:0.13,0.45; p Economic growth in Mongolia from 2000 to 2010 resulted in an increase in the effect of social determinants of child health; whilst focused policy improved access to immunisation. Children with less educated mothers and lower household incomes should be targeted in interventions to reduce health inequity.

  15. The current economic and financial crisis: a gender perspective

    OpenAIRE

    Antonopoulos, Rania

    2009-01-01

    Widespread economic recessions and protracted financial crises have been documented as setting back gender equality and other development goals in the past. In the midst of the current global crisis--often referred to as "the Great Recession"--there is grave concern that progress made in poverty reduction and women's equality will be reversed. Indeed, for many developing countries it is particularly worrisome that, through no fault of their own, the global economic downturn has exacerbated ef...

  16. Positive and Negative Factors of Economic Development in Economic History of South Korea

    Directory of Open Access Journals (Sweden)

    Park Jong Min

    2017-01-01

    in countries with a developed economies and lead to an economic crisis. Conclusions and Relevance: for the last century, the changes that happened in the economic history of the Republic of Korea made it the model case of progressive economic development of developing countries. The history of Korea's economic development suggests presence of both positive and negative factors. Within the positive factors of the economic development of the Republic of Korea it is possible to note: planning of economic development, a potential for development of technology, ability to control currency, financial crisis management and free trade agreements. Negative factors for economic development were the loss of national sovereignty, disturbances in political, economic and social fields. In addition, people's desire to develop the national economy shows that the economic development could be accomplished successfully. 

  17. Economics of ALMR deployment

    International Nuclear Information System (INIS)

    Delene, J.G.; Fuller, L.C.; Hudson, C.R.

    1994-01-01

    The Advanced Liquid Metal Reactor (ALMR) has the potential to extend the economic life of the nuclear option and of reducing the number of high level waste repositories which will eventually be needed in an expanding nuclear economy. This paper reports on an analysis which models and evaluates the economics of the use of ALMRs as a component of this country's future electricity generation mix. The ALMR concept has the ability to utilize as fuel the fissile material contained in previously irradiated nuclear fuel (i.e., spent fuel) or from surplus weapons grade material. While not a requirement for the successful deployment of ALMR power plant technology, the reprocessing of spent fuel from light water reactors (LWR) is necessary for any rapid introduction of ALMR power plants. In addition, the reprocessing of LWR spent fuel may reduce the number of high level waste repositories needed in the future by burning the long-lived actinides produced in the fission process. With this study, the relative economics of a number of potential scenarios related to these issues are evaluated. While not encompassing the full range of all possibilities, the cases reported here provide an indication of the potential costs, timings, and relative economic attractiveness of ALMR deployment

  18. Rapid Geophysical Surveyor

    International Nuclear Information System (INIS)

    Roybal, L.G.; Carpenter, G.S.; Josten, N.E.

    1993-01-01

    The Rapid Geophysical Surveyor (RGS) is a system designed to rapidly and economically collect closely-spaced geophysical data used for characterization of US Department of Energy waste sites. Geophysical surveys of waste sites are an important first step in the remediation and closure of these sites; especially older sites where historical records are inaccurate and survey benchmarks have changed because of refinements in coordinate controls and datum changes. Closely-spaced data are required to adequately differentiate pits, trenches, and soil vault rows whose edges may be only a few feet from each other. A prototype vehicle designed to collect magnetic field data was built at the Idaho National Engineering Laboratory (INEL) during the summer of 1992. The RGS was funded by the Buried Waste Integrated Demonstration program. This vehicle was demonstrated at the Subsurface Disposal Area (SDA) within the Radioactive Waste Management Complex at the INEL in September 1992. Magnetic data were collected over two areas in the SDA, with a total survey area of about 1.7 acres. Data were collected at a nominal density of 2 1/2 in. along survey lines spaced 1-ft apart. Over 350,000 data points were collected over a 6 day period corresponding to about 185 worker-days using conventional ground survey techniques

  19. China Update: Economic Reforms and Political Realities.

    Science.gov (United States)

    Eaton, Jana Sackman

    1999-01-01

    Illustrates that China has been undergoing an unprecedented rapidity of change. Discusses the high unemployment rates, job markets, reform movements, differences in economic equality, the role of the National People's Congress, and the changing political climate. Reveals that freedom is subtly beginning to permeate the lives of Chinese citizens.…

  20. Quest for a New Paradigm in Economics - A Synthesis of Views of the New Economics Working Group

    Directory of Open Access Journals (Sweden)

    Garry Jacobs

    2017-05-01

    Full Text Available The remarkable economic achievements of the past two centuries have cast an illusion of omniscience on the discipline of Economics, which even repeated catastrophic policy failures have still not entirely banished. The gap and disjuncture between prevailing economic wisdom and its effective application to promote human welfare and well-being are enormous and widening rapidly. The gap between current economic performance and the economic potential of global society has never been greater. Both have been aggravated by the rapid evolution of economy and society in recent decades. An ideology masquerading as scientific theory, mainstream theory fails to provide the necessary insights to guide us through the next phase of global social evolution. This paper summarizes major conclusions from a series of meetings organized by the World Academy of Art & Science over the past half-decade. It examines important premises and principles of a transdisciplinary framework for ecologically-sustainable, human-centered development founded on knowledge of the underlying social processes that govern human accomplishment and social evolution. It challenges the implicit values and assumptions on which current theory and practice are based. It exposes the central role played by social power in determining the operations of economy and the distribution of benefits in society. It seeks to construct a holistic paradigm to reunite and integrate thinking about economy with the political, legal, social, organizational, ecological and psychological dimensions of which economy has always been an inseparable part. It points to the need for a transnational theoretical framework as a unit of analysis and emphasizes a global perspective, which aims to maximize the well-being of humanity as a whole. In recent times, growing awareness of the limitations of the present economic system and the real planetary boundaries and ecological constraints on unlimited growth has overshadowed

  1. Advances in developing rapid, reliable and portable detection systems for alcohol.

    Science.gov (United States)

    Thungon, Phurpa Dema; Kakoti, Ankana; Ngashangva, Lightson; Goswami, Pranab

    2017-11-15

    Development of portable, reliable, sensitive, simple, and inexpensive detection system for alcohol has been an instinctive demand not only in traditional brewing, pharmaceutical, food and clinical industries but also in rapidly growing alcohol based fuel industries. Highly sensitive, selective, and reliable alcohol detections are currently amenable typically through the sophisticated instrument based analyses confined mostly to the state-of-art analytical laboratory facilities. With the growing demand of rapid and reliable alcohol detection systems, an all-round attempt has been made over the past decade encompassing various disciplines from basic and engineering sciences. Of late, the research for developing small-scale portable alcohol detection system has been accelerated with the advent of emerging miniaturization techniques, advanced materials and sensing platforms such as lab-on-chip, lab-on-CD, lab-on-paper etc. With these new inter-disciplinary approaches along with the support from the parallel knowledge growth on rapid detection systems being pursued for various targets, the progress on translating the proof-of-concepts to commercially viable and environment friendly portable alcohol detection systems is gaining pace. Here, we summarize the progress made over the years on the alcohol detection systems, with a focus on recent advancement towards developing portable, simple and efficient alcohol sensors. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. History or histories of socio-economic rights?

    DEFF Research Database (Denmark)

    Christiansen, Christian O.

    2016-01-01

    The German historian Reinhart Koselleck was once described as a partisan for histories in the plural (as opposed to history in the singular). His point was that history has many different layers, logics, and temporalities and that the modernist idea of one, overarching history with one direction ......) at work in the histories and dynamics of socio-economic rights. More specifically, I propose a list of eight important variables that may help explain the dynamics of the histories of socio-economic rights - their failures as well as their successes....... (telos) – be it towards progress or decline – was inadequate for the multi-faceted geographies, rhythms and dynamics of life. In these reflections on a two-days research workshop in Paris, I argue that Koselleck’s point also applies to the field of the history of socio-economic rights. Instead of writing...... the history of socio-economic rights, I would propose thinking about the histories of socio-economic rights. There are three main reasons for this: the non-teleological histories of socioeconomic rights; the distinctiveness between different socio-economic rights; and the complexity (multiple variables...

  3. Structural Change, Economic Growth and the Environmental Kuznets Curve. A Theoretical Perspective

    International Nuclear Information System (INIS)

    De Groot, H.L.F.

    1999-01-01

    The question of whether economic growth will ultimately resolve environmental problems has recently been discussed in a mainly empirical literature. One of the mechanisms that can explain the finding of an inverted U-shaped relationship between income and emissions relies on the changes in the sectoral composition of economies associated with economic growth. This paper develops a multi-sector general-equilibrium model to study the dynamic relationships between technological progress, economic development, the sectoral composition of economies and emissions. In the model, structural change is the outcome of a complex interplay between factors of demand and supply, and results from both differences in technological progress on a sectoral level and from differences in income elasticities of demand for different goods. We will derive under what conditions such changes can give rise to a hump-shaped relationship between per capita income and emissions. 39 refs

  4. Economic analysis of KNGR's conceptual design

    International Nuclear Information System (INIS)

    Roh, Myung-Sub; Chung, Kyung-Nam; Hong, Jang-Hee

    1997-01-01

    During the last two decades in Korea, with the rapid economic growth and industrialization, nuclear power has played an important role in electric power production. At present, Korea has 11 nuclear units in operation with total installed capacity of 9,916MWe and 7 units under construction with total capacity of 6,100MWe. An advanced reactor development program, called Korean Next Generation Reactor (KNGR), has been started for the coming 21st century. It aims to enhance safety features compared to existing plants and follow the target to maintain the economic competitiveness of nuclear energy with alternative energy sources. In order to meet these requirements, a number of technical and economical factors have been taken into the program. These factors include the economy of plant size, design simplification and optimization, and reduction of construction period. This paper addresses the preliminary economic analysis results for the KNGR design. It is indicated that KNGR has about 17% economic advantage compared to the current 1,000 MWe PWR. This paper also describes some of the experiences gained and important factors related to reducing the investment and operation costs. 5 refs., 2 figs., 5 tabs

  5. Community colleges and economic mobility

    OpenAIRE

    Natalia A. Kolesnikova

    2010-01-01

    This paper examines the role of community colleges in the U.S. higher education system and their advantages and shortcomings. In particular, it discusses the population of community college students and economic returns to community college education for various demographic groups. It offers new evidence on the returns to an associate's degree. Furthermore, the paper uses data from the National Survey of College Graduates to compare educational objectives, progress, and labor market outcomes ...

  6. Economic Growth in the Republic of Yemen : Sources, Constraints, and Potentials

    OpenAIRE

    World Bank

    2002-01-01

    High and sustained rate of economic growth in Yemen is a necesary, though not sufficient, condition for reduction of the high incidence of poverty and for raising the living standards of Yemeni citizens. Evidence in this report suggests that the main obstacle to rapid and sustained economic growth is the weak governance that characterizes Yemen in addition to the weaknesses in domestic sec...

  7. Science, democracy and emerging threats to scientific progress.

    Science.gov (United States)

    Feller, Stephan M

    2012-08-23

    Can trustworthy science flourish in countries suffering from dictatorship? This is an increasingly relevant question. Many commercial publishers want to maximise their profits (as is to be expected in a capitalistic system) and are pushing into non-democratic countries with rapid economic growth like China. But how much can we trust the papers coming from countries with dictatorial regimes?

  8. An evaluation grid for the assessments of macro-economic impacts of energy transition. Working paper Nr 48

    International Nuclear Information System (INIS)

    Ouvrard, Jean-Francois; Scapecchi, Pascale

    2014-05-01

    This study aims at comparing the main available macro-economic models used to assess the consequences of policies for energy transition, and at determining their scope and limitations of validity. More precisely, the authors study the impact of two categories of policy instruments (those aimed at modifying prices and incentive ones) and the role of the adopted modelling of technical progress and of the macro-economic closure of the model. In a first part, they present various tools or models used to assess economic impacts of energy transition: technical-economic, macro-economic, general balance, and hybrid models. Then, after a presentation of some principles adopted to analyse these various models, the authors discuss price-based tools, tools based on demand support, the key role of technological progress, the impact of the macro-economic closure on the reached objective. They finally discuss the results obtained by applying an evaluation grid to energy transition scenarios. A set of recommendations is finally proposed for a better assessment of these impacts

  9. HOW TO SUSTAIN ECONOMIC PERFORMANCE? ECONOMIC GROWTH AND ITS IMPACT FACTORS

    Directory of Open Access Journals (Sweden)

    OANA SIMONA HUDEA (CARAMAN

    2012-05-01

    Full Text Available This paper intends to render several important factors of impact on economic growth and to describe the particular types of relationships of the latter with each one of its influencing elements. In order to correctly determine such issue, we have resorted to three carefully selected models that have been estimated and compared so as to identify the most adequate and representative regression. For this purpose we have performed an analysis based on cross-section annual data for 105 countries spread all over the world. After having tested and rejected certain exogenous variables initially considered, such as imports or exports, we have finally retained the external debt and foreign direct investments as explanatory items of the dependent variable. The results revealed that both of them positively affect the gross domestic product of the analysed countries, this one being inelastic in relation to the exogenous variables considered. Even if the relationship between the economic growth and the external debt of a country is usually negative, as the money exit out of the country due to the debt service causes non-achieved potential investments, yet, there is an inflexion point up to which the external debt has a positive influence on economic growth by the increase of the investments funds acquired as result of the external credit contracting, this being the case reflected by our study. As for the relationship existing between foreign direct investments and GDP, the economic theory confirms that FDI and economic growth are directly correlated, the former contributing to technical progress, production increase and, finally, to the improvement of the living standard.

  10. Economic impact of GM crops

    Science.gov (United States)

    Brookes, Graham; Barfoot, Peter

    2014-01-01

    A key part of any assessment of the global value of crop biotechnology in agriculture is an examination of its economic impact at the farm level. This paper follows earlier annual studies which examined economic impacts on yields, key costs of production, direct farm income and effects, and impacts on the production base of the four main crops of soybeans, corn, cotton and canola. The commercialization of genetically modified (GM) crops has continued to occur at a rapid rate, with important changes in both the overall level of adoption and impact occurring in 2012. This annual updated analysis shows that there have been very significant net economic benefits at the farm level amounting to $18.8 billion in 2012 and $116.6 billion for the 17-year period (in nominal terms). These economic gains have been divided roughly 50% each to farmers in developed and developing countries. GM technology have also made important contributions to increasing global production levels of the four main crops, having added 122 million tonnes and 230 million tonnes respectively, to the global production of soybeans and maize since the introduction of the technology in the mid-1990s. PMID:24637520

  11. The Philippine economic mystery

    OpenAIRE

    Robert H. Nelson

    2007-01-01

    The poor economic performance of the Philippines over the long term is a puzzle and an apparent anomaly for the region. The decline in the Philippines' global position from the first part of the 20th century is particularly striking when viewed against the backrdrop of rapid income gains in countries of East and Southeast Asia, countries the Philippines used to surpass in terms of physical and human capital. While there have been a number of attempts to explain the puzzle—difficult geography,...

  12. The consequences of rapid deforestation: A North African example

    International Nuclear Information System (INIS)

    Zaimeche, S.E.

    1994-01-01

    This paper discusses some of the consequences of deforestation in Algeria. It focuses on the Wilaya region of Jijel, in the eastern part of the country, which has some of the last, dense, sub-humid Mediterranean forests. The issue of a possible connection between the recent widespread deforestation and the drier conditions affecting the region is discussed. It is also shown how rapid social and economic changes have induced deforestation on such a large scale that erosion and soil losses are reaching unprecedented levels. The paper also points to the loss of economic potential for Algeria's forests. 38 refs, 2 figs, 3 tabs, 3 photos

  13. Socio-economic perspectives on shifting cultivation landscapes in Northern Laos

    DEFF Research Database (Denmark)

    Heinimann, Andreas; Hett, Cornelia; Hurni, Kaspar

    2013-01-01

    Despite the rapid agricultural transition that has occurred in the past decade, shifting cultivation remains a widespread agricultural practice in the northern uplands of Lao PDR. Little information is available on the basic socio-economic situation and respective possible patterns in shifting cu...... minorities, pointing to multi-dimensional marginality of these areas. We discuss whether economic growth and increased market accessibility are sufficient to lift these landscapes out of poverty....

  14. Population and economics.

    Science.gov (United States)

    Wright, W

    1995-06-01

    The first world consists of the developed industrial countries, the second consists of rapidly developing countries, and the third of less developed, largely pre-industrial countries. The economies of most developed countries in recent years have been relatively stagnant. Most people in the developed world therefore assume that the bottom of the business cycle has arrived and that an upturn will soon be forthcoming. With the exception of the USA and Chile, which have been moderately prosperous in the last few years, the bottom has persisted for a very long time. Indeed, the developed world is not caught in a conventional business cycle, but in something quite new and different. The first world is struggling to stay at the top of countries worldwide both economically and politically, but the second world is rapidly catching up. Populations in these latter countries are both better educated and willing to work harder per unit of capital compared to people in the first world. Marketplace forces and the communication highway are increasingly bring about a scenario in which the first and second worlds will be economic peers. Faced with increased competition from the second world and a larger number of countries capable of providing foreign aid to the third world, it should be clear that the first world will turn inward and reduce its annual aid contributions to less developed countries. It is, however, in the first world's interest to promote family planning toward the goal of reduced population growth. Developed countries should insist that a substantial fraction of whatever foreign aid is provided goes toward reducing the rate of population growth. The first priority should be to make contraceptives available and promote their use worldwide. Efforts should then be taken to empower women through educational and other programs. This approach will slow population growth and improve the economic productivity of both men and women. The Third World should also seriously

  15. Rapid and Automated Determination of Plutonium and Neptunium in Environmental Samples

    DEFF Research Database (Denmark)

    Qiao, Jixin

    This thesis presents improved analytical methods for rapid and automated determination of plutonium and neptunium in environmental samples using sequential injection (SI) based chromatography and inductively coupled plasma mass spectrometry (ICP-MS). The progress of methodology development...... and optimization for rapid determination of plutonium in environmental samples using SIextraction chromatography prior to inductively coupled plasma mass spectrometry (Paper III); (3) Development of an SI-chromatographic method for simultaneous determination of plutonium and neptunium in environmental samples...... for rapid and simultaneous determination of plutonium and neptunium within an SI system (Paper VI). The results demonstrate that the developed methods in this study are reliable and efficient for accurate assays of trace levels of plutonium and neptunium as demanded in different situations including...

  16. Nanoscale microstructure effects on hydrogen behavior in rapidly solidified aluminum alloys

    Energy Technology Data Exchange (ETDEWEB)

    Tashlykova-Bushkevich, Iya I. [Belarusian State University of Informatics and Radioelectronics, Minsk (Belarus)

    2015-12-31

    The present work summarizes recent progress in the investigation of nanoscale microstructure effects on hydrogen behavior in rapidly solidified aluminum alloys foils produced at exceptionally high cooling rates. We focus here on the potential of modification of hydrogen desorption kinetics in respect to weak and strong trapping sites that could serve as hydrogen sinks in Al materials. It is shown that it is important to elucidate the surface microstructure of the Al alloy foils at the submicrometer scale because rapidly solidified microstructural features affect hydrogen trapping at nanostructured defects. We discuss the profound influence of solute atoms on hydrogen−lattice defect interactions in the alloys. with emphasis on role of vacancies in hydrogen evolution; both rapidly solidified pure Al and conventionally processed aluminum samples are considered.

  17. SOLID WASTE MANAGEMENT IN UKRAINE AS A FACTOR OF ECONOMIC PROGRESS

    OpenAIRE

    Лункіна, Т. І.; Каратай, Т. М.

    2017-01-01

    The article describes methods for recycling of municipal solid waste, their advantages and disad-vantages. Economically, the necessity of disposing of municipal solid waste and noted the relevance of this issue for our country. It highlighted the current situation and development trends in the sphere of waste management through the analysis of the «Concept of the national treatment program to waste». In the article the existent state of the system of handling with hard domestic wastes is anal...

  18. Zero energy homes – Are they economically viable?

    International Nuclear Information System (INIS)

    Berry, Stephen; Davidson, Kathryn

    2015-01-01

    Whilst net zero energy homes are espoused in many policy circles, and many bespoke examples have been constructed to demonstrate their technical feasibility, there is a scarcity of evidence demonstrating such a standard would be economically rational, particularly for large scale housing development where orientation and aspect may not always be optimal. Drawing on energy monitoring evidence and construction economics associated with a nearly zero energy housing estate in Adelaide, Australia, this paper explores the economic feasibility of the net zero energy home policy in warm temperate climates. The results demonstrate that using economic tools and assumptions typically applied for building energy regulatory policy changes, net societal economic benefits significantly outweigh costs. The clear economic outcomes, combined with expected health and productivity benefits from improved levels of thermal comfort, should provide security to policy makers to progress home energy standards towards net zero energy performance. -- Highlights: •The concept of net zero energy homes is examined for economic viability. •Evidence is collected from a near net zero energy housing estate. •Conservative results show that societal benefits outweigh costs. •Significant additional benefits gained from net zero energy homes

  19. Long-Run Nexus between Tax Revenue on Economic Performance: Empirical Evidence from Malaysia

    OpenAIRE

    Roshaiza Taha; Nanthakumar Loganathan

    2014-01-01

    Taxation is main source of government income and has direct linkages with economic performance for most of countries. This study attempts to investigate the long-run nexus between economic performance and tax revenue for Malaysia as a developing nation with dynamic economic progress for the last 2 decades. To determine the long-run nexus, we used the structural breaks effects with the conjunction of ARDL cointegration analysis along with causality analysis. The empirical finding successfully ...

  20. The Eurasian Economic Union and the Silk Road Economic Belt: Opportunities for Russia

    Directory of Open Access Journals (Sweden)

    Igor Makarov

    2016-09-01

    Full Text Available This article considers the opportunities for Russia presented by the launch of China’s Silk Road Economic Belt initiative.This initiative is a comprehensive project for the rapid development of Central Asian countries, and not limited only to transportand logistics to guarantee the supply of Chinese goods to Europe. It is also China’s response to economic and political processes both within the country and in the Asia-Pacific region: the economic slow down and transformation of its social and economic model, diverging income levels, the growing presence of the United States in Asia, and the new divisions of labour within the region. The Silk Road initiative is based on China’s intention to create strong regional value chains, to outsource labour-intensive and environmentally harmful production, to foster the development of north west China including securing political stability in the Xinjiang Uighur Autonomous Region, and to guarantee the use of Chinese construction firms’ capacity. Goods transit is a secondary priority and justified not by commercial benefits from using land routes, but by the need to diversify export risks, arising due to the deteriorating military and political situation in the South China Sea. The 2015 Joint Statement on Cooperation on the Construction of Joint Eurasian Economic Union and the Silk Road Economic Belt projects resolves the issue of all egedly competitive goals of these complementary projects. The Eurasian Economic Union (EEU provides an institutional base for cooperation while the Silk Road initiative provide investments for their development. Russia may benefit from participating in the Silk Road initiative. First, it would help integrate its transportation system into the region’s logistics network and provide additional opportunities for transit and associated logistical services as well as access to growing regional markets. Second, the Silk Road initiative offers opportunities to strengthen

  1. Economic instruments for waste management

    International Nuclear Information System (INIS)

    Malaman, R.

    1991-01-01

    Economic instruments for the implementation of environmental policies distinguish themselves from traditional tools (the 'command and control' type) for the reason that: they influence the costs and the benefits of the economic agents in question; they change the behaviour of the subjects in question in a way that they guarantee behaviour trends less harmful to the environment; they guarantee the assignment of adequate prices to the natural resources that traditionally don't have a price and therefore are consumed excessively by the economic subjects; normally they impose the transfer of economic resources to the disadvantage of the subjects responsible for the phenomena of pollution; certain objective pollution reduction data guarantee the minimization of the social costs of pollution abatement, that is, of the total costs on the economic system in general (economists define this characteristic as the 'static efficiency'); they guarantee what is called in economical jargon, the dynamic efficiency, i.e., in practice, they determine a continuous incentive for the reduction of the emission of the various pollutants and for the realization of the technological innovations that are able to control the pollution; they are more flexible than the instruments of direct regulation, because they leave the subjects a freedom of choice under different price conditions than in the past; they are flexible as well for the reason that the public operator can intervene rapidly to change the way of application

  2. Evaluation of a rapid immunodiagnostic test kit for rabies virus.

    Science.gov (United States)

    Kang, BoKyu; Oh, JinSik; Lee, ChulSeung; Park, Bong-Kyun; Park, YoungNam; Hong, KyungSoo; Lee, KyungGi; Cho, ByungKi; Song, DaeSub

    2007-10-01

    A rapid immunodiagnostic test kit for rabies virus detection was evaluated using 51 clinical samples and 4 isolates of rabies virus. The quick detection of rabies virus under field conditions may be helpful in determining if post-exposure prophylaxis is needed, thereby avoiding unnecessary treatments, as well as undue economic burden. There are several widely used diagnostic methods for rabies, including fluorescent antibody tests, reverse transcription polymerase chain reaction, and electron microscopy; however, these methods include time-consuming, intricate, and costly procedures. The rapid immunodiagnostic test was able to detect rabies virus in clinical samples, including brain tissue and saliva, in addition to 10(3.2) 50% lethal dose (LD(50))/mL cell-adapted rabies virus. The assay was not cross-reactive with non-rabies virus microbes. When the performance of the rapid immunodiagnostic test was compared to a fluorescent antibody test, the rapid immunodiagnostic test had a sensitivity of 91.7% and specificity of 100% (95.8% CI).

  3. Rapid Prototyping Technologies for Manufacturing and Maintenance Activities

    Science.gov (United States)

    Pfeifer, Marcel Rolf

    2017-12-01

    The paper deals with the direct application of Rapid Prototyping technologies for parts and spare parts production in production companies and the economic effect by making use of this technology. Traditional production technologies are technologies such as forging, cutting, machining, etc. These technologies are widely accepted and the teething troubles are solved. Rapid Prototyping technologies such as 3D printing on the other hand came into the focus in the recent years when the technologies and the produced quality gradually advanced. Providing flexibility and time efficiency the technology should also have a practical application in production. This paper has the aim to provide a case-study based on existing cost figures to show that these technologies are not limited to prototype developments.

  4. Economic development and road traffic fatalities in two neighbouring African nations

    Directory of Open Access Journals (Sweden)

    Douglas J. Wiebe

    2016-06-01

    Conclusion: Road crash fatalities increased in recent decades in both Zambia and Botswana. But the rapid economic development in Botswana over this time period appears to have driven proportionate road traffic fatality increases. There are opportunities for newly emerging economies such as Zambia, Angola, and others to learn from the Botswana experience. Evidence-based investments in road safety interventions should be concomitant with economic development.

  5. Sugammadex for reversal of neuromuscular block after rapid sequence intubation: a systematic review and economic assessment†

    Science.gov (United States)

    Chambers, D.; Paulden, M.; Paton, F.; Heirs, M.; Duffy, S.; Hunter, J. M.; Sculpher, M.; Woolacott, N.

    2010-01-01

    Summary Sugammadex 16 mg kg−1 can be used for the immediate reversal of neuromuscular block 3 min after administration of rocuronium and could be used in place of succinylcholine for emergency intubation. We have systematically reviewed the efficacy and cost-effectiveness and made an economic assessment of sugammadex for immediate reversal. The economic assessment investigated whether sugammadex appears cost-effective under various assumptions about the value of any reduction in recovery time with sugammadex, the likelihood of a ‘can't intubate, can't ventilate’ (CICV) event, the age of the patient, and the length of the procedure. Three trials were included in the efficacy review. Sugammadex administered 3 or 5 min after rocuronium produced markedly faster recovery than placebo or spontaneous recovery from succinylcholine-induced block. No published economic evaluations were found. Our economic analyses showed that sugammadex appears more cost-effective, where the value of any reduction in recovery time is greater, where the reduction in mortality compared with succinylcholine is greater, and where the patient is younger, for lower probabilities of a CICV event and for long procedures which do not require profound block throughout. Because of the lack of evidence, the value of some parameters remains unknown, which makes it difficult to provide a definitive assessment of the cost-effectiveness of sugammadex in practice. The use of sugammadex in combination with high-dose rocuronium is efficacious. Further research is needed to clarify key parameters in the analysis and to allow a fuller economic assessment. PMID:20937718

  6. Research Progress in Carbon Dioxide Storage and Enhanced Oil Recovery

    Science.gov (United States)

    Wang, Keliang; Wang, Gang; Lu, Chunjing

    2018-02-01

    With the rapid development of global economy, human beings have become highly dependent upon fossil fuel such as coal and petroleum. Much fossil fuel is consumed in industrial production and human life. As a result, carbon dioxide emissions have been increasing, and the greenhouse effects thereby generated are posing serious threats to environment of the earth. These years, increasing average global temperature, frequent extreme weather events and climatic changes cause material disasters to the world. After scientists’ long-term research, ample evidences have proven that emissions of greenhouse gas like carbon dioxide have brought about tremendous changes to global climate. To really reduce carbon dioxide emissions, governments of different countries and international organizations have invested much money and human resources in performing research related to carbon dioxide emissions. Manual underground carbon dioxide storage and carbon dioxide-enhanced oil recovery are schemes with great potential and prospect for reducing carbon dioxide emissions. Compared with other schemes for reducing carbon dioxide emissions, aforementioned two schemes exhibit high storage capacity and yield considerable economic benefits, so they have become research focuses for reducing carbon dioxide emissions. This paper introduces the research progress in underground carbon dioxide storage and enhanced oil recovery, pointing out the significance and necessity of carbon dioxide-driven enhanced oil recovery.

  7. Research Monograph on Federal International Economic Emergency Planning.

    Science.gov (United States)

    1985-10-31

    rights to use such information in the form of licenses, patents, franchises , etc. I Accordingly, for purposes of this study, we shall define economics...existence of the Washington Metropolitan Area’s rapid transit system, U.S. production of subway cars U . has ended. Consumer products ranging from

  8. Enhancing agricultural value chain for economic diversification in ...

    African Journals Online (AJOL)

    This study examined how enhancing the agricultural value chain can contribute to rapid economic diversification in Nigeria within the period of 1981-2015. The autoregressive distributed lag (ARDL) model was employed as the econometric method of estimation. The inferences were drawn at 5% significant level. The result ...

  9. Advanced and rapidly progressing head and neck cancer: good palliation following intralesional bleomycin.

    LENUS (Irish Health Repository)

    Quintyne, Keith Ian

    2011-09-01

    The authors herein report the case of a 61-year-old man undergoing adjuvant therapy for locally advanced laryngeal cancer, who developed parastomal recurrence in his radiation field around his tracheotomy site, while he was undergoing radiation therapy, and compromised the secure placement of his tracheotomy tube and maintenance of his upper airway. MRI restaging and biopsy confirmed recurrence and progressive disease in his mediastinum. He underwent local therapy with intralesional bleomycin with good palliation, and ability to maintain the patency of his upper airway.

  10. Values as Motivation Factors of Economic Behaviour

    Directory of Open Access Journals (Sweden)

    Martin Lačný

    2013-12-01

    Full Text Available The article presents a reflection on the structure of values functioning as motivators of economic behaviour. Considering the principle of rational egoism the author describes three segments of crucial values, which seem to be fundamental, as a matter of the contemporary Euro-American economic value system – freedom and justice; responsibility and confidence; progress, prosperity and rationality. An important methodological basis of presented reflection is the Ethics of social consequences – dynamically developing consequentialist ethical theory, responding to the challenges arising in the field of applied ethics in the framework of efforts to solve practical problems of today's world.

  11. Science, democracy and emerging threats to scientific progress

    Science.gov (United States)

    2012-01-01

    Can trustworthy science flourish in countries suffering from dictatorship? This is an increasingly relevant question. Many commercial publishers want to maximise their profits (as is to be expected in a capitalistic system) and are pushing into non-democratic countries with rapid economic growth like China. But how much can we trust the papers coming from countries with dictatorial regimes? PMID:22916710

  12. Science, democracy and emerging threats to scientific progress

    Directory of Open Access Journals (Sweden)

    Feller Stephan M

    2012-08-01

    Full Text Available Abstract Can trustworthy science flourish in countries suffering from dictatorship? This is an increasingly relevant question. Many commercial publishers want to maximise their profits (as is to be expected in a capitalistic system and are pushing into non-democratic countries with rapid economic growth like China. But how much can we trust the papers coming from countries with dictatorial regimes?

  13. Too much of a good thing? Economic growth and human rights, 1960 to 2010.

    Science.gov (United States)

    Cole, Wade M

    2017-09-01

    Despite widespread belief in the benefits of economic growth, some scholars emphasize the potentially negative consequences of growth-and especially rapid growth-for social and political outcomes. Using data for 149 countries between 1960 and 2010, I analyze the effect of economic growth on fundamental human rights conditions. Dynamic random-effects and two-way fixed-effects estimators, both with and without instrumental variables, yield several conclusions. First, economic growth is causally prior to rights conditions. Second, economic growth has a modest positive effect on human rights, albeit with diminishing returns at high growth rates. Third, low-income countries account for much of this relationship: growth improves rights conditions for most low-income countries, but extremely rapid growth is inimical. Growth has little effect among middle-income countries, while for high-income countries the relationship is positive but not robust. I bring these findings to bear on long-standing debates between proponents and critics of modernization theory. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Rapid thermal conditioning of sewage sludge

    Science.gov (United States)

    Zheng, Jianhong

    shows the fundamental importance of rapid processing. Rapid thermal conditioning may be incorporated into a wastewater treatment plant where biological treatment is used. For purposes of a concrete example, flow-sheets for the incorporation of the RTC process into the New York City Wards Island WPCP were prepared, and experimental data from the laboratory scale RTC test facility were used to set design parameters. A design incorporating nitrogen removal into the RTC flow sheet was also examined. ASPEN software was used to design the proposed processes and perform economic analyses. Cost estimates for these alternatives show a substantial advantage to implement RTC in comparison to present plant operation. About one third of the current sludge processing cost can be saved by incorporation of RTC into the Wards Island Plant. With nitrogen removal, the economics are even more attractive.

  15. Albania; Poverty Reduction Strategy Paper Progress Report

    OpenAIRE

    International Monetary Fund

    2003-01-01

    This paper examines the Progress Report for Albania’s National Strategy for Socio-Economic Development (NSSED). 2002 was the first year of implementing the NSSED. The implementation process has been oriented toward achieving the annual objectives and in accordance with the program of public priority measures for 2002–04. The experience gained in NSSED implementation, the definition and improvements to objectives and medium-term NSSED measures, the Millennium Development Goals, and Albania’s E...

  16. Students' Progress throughout Examination Process as a Markov Chain

    Science.gov (United States)

    Hlavatý, Robert; Dömeová, Ludmila

    2014-01-01

    The paper is focused on students of Mathematical methods in economics at the Czech university of life sciences (CULS) in Prague. The idea is to create a model of students' progress throughout the whole course using the Markov chain approach. Each student has to go through various stages of the course requirements where his success depends on the…

  17. A progress review of Ontario Hydro's nuclear generation and heavy water production programs

    International Nuclear Information System (INIS)

    Kee, F.J.; Woodhead, L.W.

    Performance and economics of CANDU reactors in service are described. Progress of commissioning, construction and planning of reactors at Pickering, Bruce, and Darlington is outlined. Heavy water production is reviewed. (E.C.B.)

  18. Bifurcations of a class of singular biological economic models

    International Nuclear Information System (INIS)

    Zhang Xue; Zhang Qingling; Zhang Yue

    2009-01-01

    This paper studies systematically a prey-predator singular biological economic model with time delay. It shows that this model exhibits two bifurcation phenomena when the economic profit is zero. One is transcritical bifurcation which changes the stability of the system, and the other is singular induced bifurcation which indicates that zero economic profit brings impulse, i.e., rapid expansion of the population in biological explanation. On the other hand, if the economic profit is positive, at a critical value of bifurcation parameter, the system undergoes a Hopf bifurcation, i.e., the increase of delay destabilizes the system and bifurcates into small amplitude periodic solution. Finally, by using Matlab software, numerical simulations illustrate the effectiveness of the results obtained here. In addition, we study numerically that the system undergoes a saddle-node bifurcation when the bifurcation parameter goes through critical value of positive economic profit.

  19. Gaming and the Commodities Market: An Economic-Based Game for Developing Reasoning Skills

    Science.gov (United States)

    Witschonke, Christopher; Herrera, Jose Maria

    2013-01-01

    The authors describe an economics-based game they have developed to instruct student teachers in the value of games and gaming for developing reasoning and decision-making skills in economics in K-12 students (5-18-year-olds). The game is designed to progress through each grade level so that by high school students have a thorough appreciation and…

  20. An assessment of progress towards universal health coverage in Brazil, Russia, India, China, and South Africa (BRICS).

    Science.gov (United States)

    Marten, Robert; McIntyre, Diane; Travassos, Claudia; Shishkin, Sergey; Longde, Wang; Reddy, Srinath; Vega, Jeanette

    2014-12-13

    Brazil, Russia, India, China, and South Africa (BRICS) represent almost half the world's population, and all five national governments recently committed to work nationally, regionally, and globally to ensure that universal health coverage (UHC) is achieved. This analysis reviews national efforts to achieve UHC. With a broad range of health indicators, life expectancy (ranging from 53 years to 73 years), and mortality rate in children younger than 5 years (ranging from 10·3 to 44·6 deaths per 1000 livebirths), a review of progress in each of the BRICS countries shows that each has some way to go before achieving UHC. The BRICS countries show substantial, and often similar, challenges in moving towards UHC. On the basis of a review of each country, the most pressing problems are: raising insufficient public spending; stewarding mixed private and public health systems; ensuring equity; meeting the demands for more human resources; managing changing demographics and disease burdens; and addressing the social determinants of health. Increases in public funding can be used to show how BRICS health ministries could accelerate progress to achieve UHC. Although all the BRICS countries have devoted increased resources to health, the biggest increase has been in China, which was probably facilitated by China's rapid economic growth. However, the BRICS country with the second highest economic growth, India, has had the least improvement in public funding for health. Future research to understand such different levels of prioritisation of the health sector in these countries could be useful. Similarly, the role of strategic purchasing in working with powerful private sectors, the effect of federal structures, and the implications of investment in primary health care as a foundation for UHC could be explored. These issues could serve as the basis on which BRICS countries focus their efforts to share ideas and strategies. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Work performance and tax compliance in flat and progressive tax systems

    NARCIS (Netherlands)

    Pantya, Jozsef; Kovacs, Judit; Kogler, C.; Kirchler, Erich

    2016-01-01

    Different tax systems, and their impact on work motivation and tax compliance are significant issues in contemporary political and economic debates. The proportional feature of a flat tax system is assumed to lead to higher performance, while the fairness of the redistributive progressive tax system

  2. Public health interventions: evaluating the economic evaluations

    Directory of Open Access Journals (Sweden)

    Martin Forster

    2013-10-01

    Full Text Available Recent years have witnessed much progress in the incorporation of economic considerations into the evaluation of public health interventions. In England, the Centre for Public Health Excellence within the National Institute for Health and Care Excellence works to develop guidance for preventing illness and assessing which public health interventions are most effective and provide best value for money...

  3. Rapid in situ gamma spectrometric determination of fallout radioactivity in the environment. Progress report

    International Nuclear Information System (INIS)

    Zombori, Peter

    1995-01-01

    The main aim of the present CRP is to identify the existing analytical methods and develop new ones, if possible, which provide rapid, reliable, and detailed information on the radioactive contamination of the environment after a major nuclear accident. Gamma spectrometry has long been regarded as one of the most applicable radioanalytical techniques but its use for environmental studies requires some further considerations. There are two possible approaches to measure environmental radioactivity: (a) taking samples of the different environmental media and measuring them in a laboratory or (b) taking the spectrometer to the place of interest and making in situ measurements. In the former case sampling is a crucial factor hindering the rapid analysis while the latter case is not always reliable due to the problems and uncertainties of the measurement interpretation. The application of in situ gamma spectrometry for the determination of environmental radioactivity has become increasingly attractive since the advent of the high resolution semiconductor gamma detectors, especially, more recently, portable high purity Ge diodes (HpGe). The applicability of this technique was very well proved after the Chernobyl reactor accident when in situ spectrometry played an important role in the rapid evaluation of the fall-out situation. Our measurements provided information on the amount and composition of the radioactive contamination of the ground surface already in the first hours. These measurements enabled us to predict the time variation of the environmental radioactivity after the stabilization of the situation. The portability of the system was an important factor in performing a rapid and efficient survey in different parts of the country. A serious disadvantage of this method is, however, that it requires some knowledge about the radionuclide distribution in the soil, which is normally determined by tedious and time consuming sample analysis of the different soil

  4. Corporate sustainability: environmental, social, economic and corporate performance

    Directory of Open Access Journals (Sweden)

    Alena Kocmanová

    2011-01-01

    Full Text Available The article deals with corporate sustainability and environmental and social issues of the integration of corporate performance measurement that may lead to sustainable economic success. Sustainability is a strategy of the process of sustainable development. Sustainability of businesses and sustainable performance can be defined as an integration of environmental, social and economic performance. First and foremost, businesses will want to know what indicators can be used to measure environmental, social and economic performance. What is the mutual relationship between environmental, social and economic performance? How can firms arrive at a comprehensive assessment of their performance in relation to sustainability? The aim of this paper is to analyze corporate environmental, social and economic performance and to analyze their mutual relationships. The final part of the article is an assessment of the contemporary situation and draft Key Performance Indicators (KPI for assessment of corporate sustainability that will be the subject of further research in a selected NACE-CZ sector and in accordance with Corporate Sustainability Reporting. KPI provide businesses with a means of measuring progress toward achieving objectives.

  5. Assessment of the Economic Structure of Brazilian Agribusiness

    Science.gov (United States)

    Rodrigues Moreira, Vilmar; Kureski, Ricardo; Pereira da Veiga, Claudimar

    2016-01-01

    This paper presents an economic assessment of Brazilian agribusiness and its relationship with other economic sectors. It was found that, in 2011, agribusiness had a share of 18.45% (basic prices) and 19.77% (market prices) of Brazilian GDP. The tax burden of agribusiness (20.68%) was higher than that of other sectors (13.59%), despite agribusiness being a major contributor to the generation of foreign exchange, employment, and essential products, such as food. Brazilian agribusiness is a major employer, responsible for 29.39% of national employment. However, its average income is lower than in the other sectors of the Brazilian economy. Finally, agribusiness was found to be the biggest generator of foreign exchange, with a positive balance of trade. It was possible to conclude that agribusiness forms a strong link between agriculture and livestock, industry, and services in other economic sectors. For this reason, it can be said that the development of agribusiness is highly relevant to the process of Brazilian economic development and is therefore important to the progress of economic policies. PMID:27243040

  6. Assessment of the Economic Structure of Brazilian Agribusiness.

    Science.gov (United States)

    Rodrigues Moreira, Vilmar; Kureski, Ricardo; Pereira da Veiga, Claudimar

    2016-01-01

    This paper presents an economic assessment of Brazilian agribusiness and its relationship with other economic sectors. It was found that, in 2011, agribusiness had a share of 18.45% (basic prices) and 19.77% (market prices) of Brazilian GDP. The tax burden of agribusiness (20.68%) was higher than that of other sectors (13.59%), despite agribusiness being a major contributor to the generation of foreign exchange, employment, and essential products, such as food. Brazilian agribusiness is a major employer, responsible for 29.39% of national employment. However, its average income is lower than in the other sectors of the Brazilian economy. Finally, agribusiness was found to be the biggest generator of foreign exchange, with a positive balance of trade. It was possible to conclude that agribusiness forms a strong link between agriculture and livestock, industry, and services in other economic sectors. For this reason, it can be said that the development of agribusiness is highly relevant to the process of Brazilian economic development and is therefore important to the progress of economic policies.

  7. Assessment of the Economic Structure of Brazilian Agribusiness

    Directory of Open Access Journals (Sweden)

    Vilmar Rodrigues Moreira

    2016-01-01

    Full Text Available This paper presents an economic assessment of Brazilian agribusiness and its relationship with other economic sectors. It was found that, in 2011, agribusiness had a share of 18.45% (basic prices and 19.77% (market prices of Brazilian GDP. The tax burden of agribusiness (20.68% was higher than that of other sectors (13.59%, despite agribusiness being a major contributor to the generation of foreign exchange, employment, and essential products, such as food. Brazilian agribusiness is a major employer, responsible for 29.39% of national employment. However, its average income is lower than in the other sectors of the Brazilian economy. Finally, agribusiness was found to be the biggest generator of foreign exchange, with a positive balance of trade. It was possible to conclude that agribusiness forms a strong link between agriculture and livestock, industry, and services in other economic sectors. For this reason, it can be said that the development of agribusiness is highly relevant to the process of Brazilian economic development and is therefore important to the progress of economic policies.

  8. Lending sociodynamics and economic instability

    Science.gov (United States)

    Hawkins, Raymond J.

    2011-11-01

    We show how the dynamics of economic instability and financial crises articulated by Keynes in the General Theory and developed by Minsky as the Financial Instability Hypothesis can be formalized using Weidlich’s sociodynamics of opinion formation. The model addresses both the lending sentiment of a lender in isolation as well as the impact on that lending sentiment of the behavior of other lenders. The risk associated with lending is incorporated through a stochastic treatment of loan dynamics that treats prepayment and default as competing risks. With this model we are able to generate endogenously the rapid changes in lending opinion that attend slow changes in lending profitability and find these dynamics to be consistent with the rise and collapse of the non-Agency mortgage-backed securities market in 2007/2008. As the parameters of this model correspond to well-known phenomena in cognitive and social psychology, we can both explain why economic instability has proved robust to advances in risk measurement and suggest how policy for reducing economic instability might be formulated in an experimentally sound manner.

  9. Progress report within the series of GRS-F progress reports on reactor safety, sponsored by the Federal Ministry of Economics and Labour. Period: 1 January - 30 June 2003

    International Nuclear Information System (INIS)

    2003-01-01

    The Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, by order of the BMWi, continuously issues information on the status of the investigations into the safety of nuclear power plants by publishing semi-annual and annual progress reports within the series of GRS-F-Fortschrittsberichte (GRS-F-Progress Reports). Each progress report represents a compilation of individual reports about the objectives, work performed, results achieved, next steps of the work etc. The individual reports are prepared in a standard form by the research organisations themselves as documentation of their progress in work and are published by the Research Management Division of GRS within the framework of general information on the progress in reactor safety research. The compilation of the reports is classified according to general topics related to reactor safety research. Further, use is made of the classification system ''Joint Safety Research Index'' of the CEC (commission of the european communities). The reports are arranged in sequence of their project numbers. (orig.) [de

  10. Progress report within the series of GRS-F progress reports on reactor safety, sponsored by the Federal Ministry of Economics and Labour. Period: 1 July - 31 December 2003

    International Nuclear Information System (INIS)

    2004-01-01

    The Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, by order of the BMWi, continuously issues information on the status of the investigations into the safety of nuclear power plants by publishing semi-annual and annual progress reports within the series of GRS-F-Fortschrittsberichte (GRS-F-Progress Reports). Each progress report represents a compilation of individual reports about the objectives, work performed, results achieved, next steps of the work etc. The individual reports are prepared in a standard form by the research organisations themselves as documentation of their progress in work and are published by the Research Management Division of GRS within the framework of general information on the progress in reactor safety research. The compilation of the reports is classified according to general topics related to reactor safety research. Further, use is made of the classification system ''Joint Safety Research Index'' of the CEC (commission of the european communities). The reports are arranged in sequence of their project numbers. (orig.) [de

  11. Economic development influences on sediment-bound nitrogen and phosphorus accumulation of lakes in China.

    Science.gov (United States)

    Ni, Zhaokui; Wang, Shengrui

    2015-12-01

    China has been confronted with serious water quality deterioration concurrent with rapid socioeconomic progress during the past 40 years. Consequently, knowledge about economic growth and lake water quality dynamics is important to understand eutrophication processes. Objectives were to (i) reconstruct historical nutrient accumulation and the basin economic progress on burial flux (BF); (ii) determine forms and structures of nitrogen (N) and phosphorus (P) in sediment and water using six cores in three of the most severely eutrophic lake areas in China (i.e., Eastern Plain, Yunnan-Guizhou Plain, and Inner Mongolia-Xinjiang regions). Results suggest that BFs of total nitrogen (TN) continued to increase in sediment, whereas total phosphorus (TP) levels were consistent or only slightly increased, except in highly polluted lakes during the past decades. Similar results were observed for concentrations of nutrients in water (i.e., increased N/P). This historical distribution pattern was correlated to long-term fertilization practices of farmers in the watershed (N fertilization exceeds that of P) and was contingent upon pollution control policies (e.g., emphasized P whereas N was ignored). Vertical profiles of BFs indicated that lake nutrient accumulation included three stages in China. Nutrient accumulation started in the 1980s, accelerated from the 1990s, and then declined after 2000. Before the 1980s, nutrients were relatively low and stable, with nutrient inputs being controlled by natural processes. Thereafter, N- and P-bound sediments dramatically increased due to the increasing influence of anthropogenic processes. Nutrients were primarily derived from industries and domestic sewage. After 2000, BFs of nutrients were steady and even decreased, owing to implementation of watershed load reduction policies. The decreasing NaOH-extracted P (Fe/Al-P) and increasing organic phosphorus (OP) indicated that the source of exogenous pollution underwent a shift. Inputs of

  12. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    International Nuclear Information System (INIS)

    Till, C.E.; Chang, Y.I.

    1993-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions

  13. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    Energy Technology Data Exchange (ETDEWEB)

    Till, C.E.; Chang, Y.I.

    1993-03-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions.

  14. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    Energy Technology Data Exchange (ETDEWEB)

    Till, C.E.; Chang, Y.I.

    1993-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions.

  15. Parameter study toward economical magnetic fusion power reactors

    International Nuclear Information System (INIS)

    Yoshida, Tomoaki; Okano, Kunihiko; Nanahara, Toshiya; Hatayama, Akiyoshi; Yamaji, Kenji; Takuma, Tadashi.

    1996-01-01

    Although the R and D of nuclear fusion reactors has made a steady progress as seen in ITER project, it has become of little doubt that fusion power reactors require hugeness and enormous amount of construction cost as well as surmounting the physics and engineering difficulties. Therefore, it is one of the essential issues to investigate the prospect of realizing fusion power reactors. In this report we investigated the effects of physics and engineering improvements on the economics of ITER-like steady state tokamak fusion reactors using our tokamak system and costing analysis code. With the results of this study, we considered what is the most significant factor for realizing economical competitive fusion reactors. The results show that with the conventional TF coil maximum field (12T), physics progress in β-value (or Troyon coefficient) has the most considerable effect on the reduction of fusion plant COE (Cost of Electricity) while the achievement of H factor = 2-3 and neutron wall load =∼5MW/m 2 is necessary. The results also show that with the improvement of TF coil maximum field, reactors with a high aspect ratio are economically advantageous because of low plasma current driving power while the improvement of current density in the conductors and yield strength of support structures is indispensable. (author)

  16. Preliminary Economic Assessment of KALIMER-600

    International Nuclear Information System (INIS)

    Moon, Kee-Hwan; Kim, Seung-Su; Hahn, Do-Hee

    2008-01-01

    The GIF(GEN IV International Forum) established an Economic Modelling Working Group(EMWG) in 2003 to create economic models and guidelines to facilitate in a future evaluation of the Generation IV nuclear energy systems and assess progress toward the GIF economic goals. These goals are to have a life cycle cost advantage over other energy sources, and to have a level of financial risk comparable to other energy projects. To do this, EMWG has been developed the G4-ECONS model, which is a generic EXCEL-based model for computation of the projected levelized unit electricity cost and/or levelized non-electricity unit product cost from GEN IV energy systems. KALIMER-600 has been developed as a new design concept based on the KALIMER-150 design. KALIMER-600 is a unique design concept which has a potential to achieve GEN IV technology goals even though there is a room for a design improvement in order to make the KALIMER-600 more competitive with future generation reactors. The objective of this study is to the assess economics of KALIMER-600 by using the G4-ECONS model

  17. The new economics of nuclear energy

    International Nuclear Information System (INIS)

    Salian, Ramesh; Prasanna Kumar, N.

    2012-01-01

    With 15% of the world's population and an economic growth rate that increases the aspiration of its people to better quality of life, India has a voracious appetite for energy. Nuclear power is one of the options of providing safe, environmentally benign, reliable and economically competitive energy services. Nuclear power world over provides about 16% of electricity through 440 nuclear power plants with a total installed capacity of 361.582 GW (as of January 2004, IAEA PRIS data). Nuclear energy has traditionally played a small role in meeting India's energy requirements. Nuclear power makes up only 4,120 MW, constituting 2.6%, of the total electricity generation capacity. India is a power hungry nation and needs to switch over from its tremendous dependence on fossil fuels to alternative sources of energy like solar energy, bio energy and nuclear energy. Indian nuclear power plants have progressively attained excellent operation performances. However, the changing economic and geopolitical situation in the energy sector has made it imperative to emphasize the significance of nuclear energy in the future energy landscape of the country. The present paper discuss the importance, demand and supply pattern of nuclear energy and its economics. (author)

  18. Social murder: the long-term effects of conservative economic policy.

    Science.gov (United States)

    Chernomas, Robert; Hudson, Ian

    2009-01-01

    In this article, the authors take inspiration from Engels's 1845 account of the social murder committed by British capitalists to assess the contemporary impact of conservative economic policy, which they define as policies designed to maximize the accumulation of profit while socializing the associated risks and costs. Conservative economists argue that if their policy prescription is followed, it will produce broad-based economic benefits including more rapid growth, higher incomes, less illness, and, even, more democracy. The authors contrast the myth of conservative economic policy with the reality. What conservative economic policy has actually accomplished is a redistribution of wealth and power away from the vast majority of the population to firms and their owners. The effects of these policies on citizens and workers have been socially determined economic instability, unemployment, poverty, inequality, dangerous products, and infectious and chronic disease.

  19. Costs and benefits of flexible workspaces : work in progress in The Netherlands

    NARCIS (Netherlands)

    van der Voordt, Theo

    2003-01-01

    Due to the rapid progress in information and communication technology, work is becoming more and more independent of time and place. New concepts such as cocon offices (with special attention to both communication and concentration), teleworking, satellite offices, and hotel offices have been

  20. Rapid desensitization induces internalization of antigen-specific IgE on mouse mast cells.

    Science.gov (United States)

    Oka, Tatsuya; Rios, Eon J; Tsai, Mindy; Kalesnikoff, Janet; Galli, Stephen J

    2013-10-01

    Rapid desensitization transiently prevents severe allergic reactions, allowing administration of life-saving therapies in previously sensitized patients. However, the mechanisms underlying successful rapid desensitization are not fully understood. We sought to investigate whether the mast cell (MC) is an important target of rapid desensitization in mice sensitized to exhibit IgE-dependent passive systemic anaphylaxis in vivo and to investigate the antigen specificity and underlying mechanisms of rapid desensitization in our mouse model. C57BL/6 mice (in vivo) or primary isolated C57BL/6 mouse peritoneal mast cells (PMCs; in vitro) were passively sensitized with antigen-specific anti-2,4-dinitrophenyl IgE, anti-ovalbumin IgE, or both. MCs were exposed over a short period of time to increasing amounts of antigen (2,4-dinitrophenyl-human serum albumin or ovalbumin) in the presence of extracellular calcium in vitro or by means of intravenous administration to sensitized mice in vivo before challenging the mice with or exposing the PMCs to optimal amounts of specific or irrelevant antigen. Rapidly exposing mice or PMCs to progressively increasing amounts of specific antigen inhibited the development of antigen-induced hypothermia in sensitized mice in vivo and inhibited antigen-induced PMC degranulation and prostaglandin D2 synthesis in vitro. Such MC hyporesponsiveness was induced antigen-specifically and was associated with a significant reduction in antigen-specific IgE levels on MC surfaces. Rapidly exposing MCs to progressively increasing amounts of antigen can both enhance the internalization of antigen-specific IgE on the MC surface and also desensitize these cells in an antigen-specific manner in vivo and in vitro. Copyright © 2013 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

  1. Small Business Financing – an Economic Growth Stimulator

    Directory of Open Access Journals (Sweden)

    Lilia Ivas

    2010-12-01

    Full Text Available Small business is an important lever for solving a whole complex of political, economic and social problems, taking into consideration its effectiveness in society. It attracts population to promote economic reforms, it fulfils the market with goods and services, it creats new job places, it grows entrepreneurial spirit and entrepreneurial culture, developes a careful attitude towards property, forms a progressive structure of the national economy. We can deduce after the research in this article that as an independent and irreplaceable structure, the small and medium enterprise sector in Moldova constitutes one of the most efficient levers that contribute at solutioning the economic and social problems. It also is a factor which structurally transforms the economy, consolidates its economic base and its zones, fulfils in an accelerate mode the market with goods and services, attenuates the monopolism and favours competition development, implementation of scientific and technical achievements, the country's increasing export opportunities, providing new jobs to a large number of people .

  2. Impacts of bus rapid transit (BRT) on surrounding residential property values : final report.

    Science.gov (United States)

    2017-07-01

    As bus rapid transit (BRT) grows in popularity in the United States, a better understanding of the modes impacts on land uses and property values is needed. Economic theory suggests, and literature has shown, that people are willing to pay higher ...

  3. Advantage or illusion: is Alberta's progress sustainable?

    Energy Technology Data Exchange (ETDEWEB)

    Anielski, M. [Pembina Institute for Appropriate Development, Drayton Valley, AB (Canada)

    2001-08-01

    A new indicator of economic and environmental well-being, the Genuine Progress Indicators, of GPI, is discussed as part of an attempt to gauge the state of health of Alberta's economy, and to establish whether the tremendous apparent economic progress made by the province in recent decades is real or illusory. The GPI, an accounting system by which nations can measure real progress and real wealth, was developed by the Pembina Institute for Appropriate Development of Alberta. It combines 51 indicators of economic, social and environmental measures, and is consistent with international efforts to find new measures of well-being and human development. Based on a study using the GPI system, real disposable income of Albertans was 5.5 per cent lower in 1999 than in 1982, despite a 36.3 per cent rise in Alberta's GDP per capita. This finding suggests that not all people are sharing in the the economic good times. Personal and household debt has also risen substantially and now exceeds real disposable income for the first time in history. Ability to save has been squeezed, resulting in protracted decline in personal savings, while Albertans pay 500 per cent more taxes in real dollars since 1961. Social and human health indicators highlight signs of social stress, such as rising levels of divorce, problem gambling and falling voter participation. Other indicators raise concerns about the condition of Alberta's natural capital, such as forests, agricultural soils, air and water quality, fish, wildlife and protected areas. Environmental GPIs show that Albertans have the fourth-highest ecological footprint in the world, exceeded only by the Arab Emirates, Singapore and the United States. The bigger the footprint the more is someone else on the planet shortchanged. The Pembina Institute report concludes that the development of Alberta's fossil fuel energy resources has come with a tremendous ecological price tag. It also shows that conventional crude oil

  4. Engaging Health Professionals in Health Economics: A Human Capital Informed Approach for Adults Learning Online

    Science.gov (United States)

    Lieberthal, Robert D.; Leon, Juan

    2015-01-01

    The authors describe a Wikipedia-based project designed for a graduate course introducing health economics to experienced healthcare professionals. The project allows such students to successfully write articles on niche topics in rapidly evolving health economics subspecialties. These students are given the opportunity to publish their completed…

  5. Human Behavior and Cognition in Evolutionary Economics.

    Science.gov (United States)

    Nelson, Richard R

    2011-12-01

    My brand of evolutionary economics recognizes, highlights, that modern economies are always in the process of changing, never fully at rest, with much of the energy coming from innovation. This perspective obviously draws a lot from Schumpeter. Continuing innovation, and the creative destruction that innovation engenders, is driving the system. There are winners and losers in the process, but generally the changes can be regarded as progress. The processes through which economic activity and performance evolve has a lot in common with evolution in biology. In particular, at any time the economy is marked by considerable variety, there are selection forces winnowing on that variety, but also continuing emergence of new ways of doing things and often economic actors. But there also are important differences from biological evolution. In particular, both innovation and selection are to a considerable degree purposive activities, often undertaken on the basis of relatively strong knowledge.

  6. Electric power, emissions and economic development

    International Nuclear Information System (INIS)

    Pearson, P.

    1996-01-01

    Energy use in the developing world has been growing rapidly over recent decades, both absolutely and relative to the growth in industrialized countries albeit from a very low base. In the next century, developing country commercial energy consumption in general and electricity consumption in particular, is expected to continue to rise with striking rapidity because of population growth, income growth and substitution of modern commercial fuels for traditional biomass fuels. Because the power sector is one of the fastest-growing energy sectors, it raises significant domestic environmental issues, while the sector's role in global warming scenarios has made it a key feature of international environmental policy. This paper focuses on the relationships between economic development, electric power and polluting emissions. 10 refs

  7. Women and social security: a progressive approach.

    Science.gov (United States)

    Olson, L K

    1994-01-01

    This article explores some major assumptions underlying the Social Security system and alternative approaches to rendering the system more economically viable, meeting the income needs of the elderly and/or providing greater equity under its benefit and taxation provisions. It attempts to show that the current structure of Social Security not only reinforces but also exacerbates the underlying economic inequalities in our nation's political economy under the guise of a social insurance program. In addressing selected benefit and taxation issues, the article focuses on how working and older women are faring in the 1990s under the Social Security system. It argues that although the program theoretically is gender neutral, its impact is not. Women, particularly those who are single, are poorly served. The article concludes that a progressive restructuring of the Social Security system itself is imperative if we are to meet the needs of a large percentage of workers, older people, and the economic and social demands of the 1990s and beyond. It also offers some suggestions for such change.

  8. Spurring Economic Growth through Education: The Malaysian Approach

    Science.gov (United States)

    Rao, R. Ramesh; Jani, Rohana

    2009-01-01

    The economic progress made by many countries is attributed to many factors. Education is often quoted as a major contributing factor. There are many researches done in evaluating and determining the role of education in nations. In this paper, factors of education which have helped in the case of Malaysia are dwelled upon. Education has helped…

  9. SELLING CANANG SARI (As an Alternative of Effort in Informal Sector to overcome household economics problem)

    OpenAIRE

    Desak Putu Eka Nilakusmawati

    2012-01-01

    Decrease in family income represent an impact of economic pressures, as an effect of economic crisis. Other side, the existing problems that extension of the job opportunity in the urban area with existence of development in the various sector do not absorb entire labour force which is progressively growing larger its amount.Economic problem force woman of lower economic class to involved take part in earning for increase family income by working beyond domestic sectors. Involvement of woman ...

  10. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    International Nuclear Information System (INIS)

    Till, C.E.; Chang, Y.I.

    1991-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions. 10 refs

  11. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    Energy Technology Data Exchange (ETDEWEB)

    Till, C.E.; Chang, Y.I.

    1991-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions. 10 refs.

  12. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    International Nuclear Information System (INIS)

    Till, C.E.; Chang, Y.I.

    1991-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions. (author)

  13. The Effects of the ASEAN Economic Community 2015 on Industries in Kitakyushu and Shimonoseki

    OpenAIRE

    エリック D., ラムステッター; Archanun, Kohpaiboon; Eric D., Ramstetter; Kohpaiboon, Archanun

    2015-01-01

    This paper asks how the formation of the Association of Southeast Asian Nations'(ASEAN's) Economic Community (AEC) in 2015 (AEC2015) will affect industries in Kitakyushu and Shimonoseki. First, ASEAN's rapid economic during the past five decades has made ASEAN a large market for Japanese goods, services, and firms. ASEAN has supported this growth by facilitating important economic and political dialogue in Southeast Asia and AEC2015 will likely reinforce this important role. Second, although ...

  14. Economic and Policy Review - Vol 13, No 3 (2007)

    African Journals Online (AJOL)

    Economic and Policy Review - Vol 13, No 3 (2007). Journal Home > Archives > Vol 13, No 3 ... Snagging the wheel of progress: Corruption, New anti-corruption drive and Nigeria\\'s quest for development. S B Kura ... Book Review: challenges of African growth opportunities, constraints and strategic directions. S I Owualah ...

  15. Process development studies on the bioconversion of cellulose and production of ethanol. Progress report, September 1, 1978

    Energy Technology Data Exchange (ETDEWEB)

    Wilke, C.R.

    1978-09-01

    Progress is reported in studies on the pretreatment of cellulosic materials to facilitate enzymatic hydrolysis, sulfuric acid hydrolysis, investigation of the Purdue processing scheme including an economic analysis, and the fermentability of the enzymatic hydrolyzate. Progress is also reported on enzyme fermentation studies, hydrolysis reactor development, and utilization of hemicellulose sugars. (JSR)

  16. Transport Infrastructure and Economic Growth: Spatial Effects

    Directory of Open Access Journals (Sweden)

    Artyom Gennadyevich Isaev

    2015-09-01

    Full Text Available The author specifies an empirical framework of neoclassical growth model in order to examine impact of transport infrastructure on economic growth in Russian regions during period of 2000-2013. Two different effects of infrastructure are considered. First, infrastructure is viewed as part of region’s own production function. Second, infrastructure generates spillover effect on adjacent regions’ economic performance which can be negative or positive. Results imply that road infrastructure has a positive influence on regional growth, but sign of railroad infrastructure coefficient depends on whether or not congestion effect is considered. Negative spillover effect is shown to exist in the case of road infrastructure. This apparently means that rapid road infrastructure development in some regions moves mobile factors of production away from adjacent regions retarding their economic development. The spillover effect of railroad infrastructure is significant and negative again only if congestion effect is considered. The results of estimation for the Far East and Baikal Regions separately demonstrate no significant effect of both types of infrastructure for economic performance and negative spillover effect of road infrastructure

  17. Temporal trends in BMI in Argentina by socio-economic position and province-level economic development, 2005-2009.

    Science.gov (United States)

    Christine, Paul J; Diez Roux, Ana V; Wing, Jeffrey J; Alazraqui, Marcio; Spinelli, Hugo

    2015-04-01

    We investigated temporal trends in BMI, and assessed hypothesized predictors of trends including socio-economic position (SEP) and province-level economic development, in Argentina. Using multivariable linear regression, we evaluated cross-sectional patterning and temporal trends in BMI and examined heterogeneity in these associations by SEP and province-level economic development with nationally representative samples from Argentina in 2005 and 2009. We calculated mean annual changes in BMI for men and women to assess secular trends. Women, but not men, exhibited a strong cross-sectional inverse association between SEP and BMI, with the lowest-SEP women having an average BMI 2.55 kg/m(2) greater than the highest-SEP women. Analysis of trends revealed a mean annual increase in BMI of 0.19 kg/m(2) and 0.15 kg/m(2) for women and men, respectively, with slightly greater increases occurring in provinces with greater economic growth. No significant heterogeneity in trends existed by individual SEP. BMI is increasing rapidly over time in Argentina irrespective of various sociodemographic characteristics. Higher BMI remains more common in women of lower SEP compared with those of higher SEP.

  18. Effects of economic crisis on the distribution of earnings from Romania

    OpenAIRE

    Amalia CRISTESCU; Dorel AILENEI

    2015-01-01

    The wage gap issue as well as that of income inequality has been a key topic in economics. The supervision of these gaps is essential in terms of labour stimulation and orientation in order to support social progress and to maintain the economic and social cohesion. Starting from a positive approach, but considering the risks of a limiting analysis, in this article, the authors analyzed the determinants of earnings inequality in Romania through an ordered-logit model. The model...

  19. The Crisis of Economic Theory in the Middle of the Economic Crisis

    Directory of Open Access Journals (Sweden)

    Silvia MĂRGINEAN

    2011-05-01

    Full Text Available Keynesian economics has lost much of its effectiveness as a paradigm of world capitalism as a whole, or as a paradigm of individual developed capitalist economies. The decline of the United States as a hegemonic power capable of imposing its will over others has seen to the erosion of the relevance of the Keynesian doctrine on the global scale. The Philips curve and what Hicks calls the “social” pressure on wages have severely restricted the field of Keynesian policy at home – even through the ruling classes continue to use Keynesian theory as their paradigm. The most important lesson from Keynes work may be that the macroeconomist should start from the important problems of the day and should face the following questions: 1 How can we to understand what are is happening right now? 2 What can be done about it? What is the best policy to follow? 3 Do recent events force us to modify what is today widely accepted economic theory? If so, what is wrong and how might we go about arriving at a more satisfying theory? The most important economic problem of today is current financial crisis that started in the United States. What might we learn from Keynesian theory about it? The current situation is almost the opposite of the one that Keynes dealt with in the “General Theory”. Now day’s economics lacks an anchored understanding of the nature of the reality that economics is supposed to illuminate. Instability of leverage, connectivity, and potential instability of the price level have all been neglected in stable – with – fractions macro theory. Technical innovations will not bring real progress as long as “stability – with – fractions” remains the ruling paradigm. Meanwhile, governments are not prepared to face another crisis.

  20. Risk of progression in macula-on rhegmatogenous retinal detachment.

    Science.gov (United States)

    Callizo, Josep; Pfeiffer, Sebastian; Lahme, Eva; van Oterendorp, Christian; Khattab, Mohammed; Bemme, Sebastian; Kulanga, Miroslav; Hoerauf, Hans; Feltgen, Nicolas

    2017-08-01

    To identify factors that may lead to a rapid progression in macula-on rhegmatogenous retinal detachment (RRD), in particular, those that may lead to macular involvement. Observational, prospective, single-center study. Patients referred for surgery due to primary rhegmatogenous retinal detachment with the macula on between 2009 and 2013 were included. Relevant factors analyzed included age, time delay until surgery, lens status, myopia, the detachment's location and configuration as well as number, size and type of retinal breaks. Eyes underwent optical coherence tomography to detect macular detachment. A multivariate analysis was performed to investigate the effect of several factors in the progression of retinal detachment. A total of 116 eyes of 116 patients were included. Mean time delay between admission and surgery was 1.8 ± 1.4 days. Progression was observed in 19.8% of the eyes. Of those, 47.8% presented macular detachment. Ten of the 11 (90.9%) eyes presenting progression involving the macula also exhibited a bullous configuration, which was the only parameter that correlated significantly with detachment progression in patients with (p = 0.0036) and without (p = 0.0014) macular involvement. For the first time in a prospective trial, a bullous configuration was found to be a highly significant predictor for progression in macula-on detachments. Our data support prompt surgery in patients diagnosed with bullous macula-on RRD.

  1. Human Capital Development in Nigeria: A Socio-Economic Analysis ...

    African Journals Online (AJOL)

    The paper establishes the link between education and selected human development indicators. Rapid socio-economic development has been observed to depend essentially on the calibre of human capital in a nation. Although Nigeria is one of the most populous nations in Africa, the country is still largely ...

  2. Acquired resistance of malarial parasites against artemisinin-based drugs: social and economic impacts

    Directory of Open Access Journals (Sweden)

    Johanna M Porter-Kelley

    2010-08-01

    Full Text Available Johanna M Porter-Kelley1, Joann Cofie2, Sophonie Jean2, Mark E Brooks1, Mia Lassiter1, DC Ghislaine Mayer21Life Sciences Department, ­Winston-Salem State University, Winston Salem, NC, USA; 2Department of Biology, Virginia Commonwealth University, Richmond, VA, USAAbstract: Malaria, a disease of poverty and high morbidity and mortality in the tropical world, has led to a worldwide search for control measures. To that end, good antimalarial chemotherapies have been difficult to find in the global market and those that seem to be most effective are rapidly becoming ineffective due to the emergence and spread of drug resistance. Artemisinin, a very effective yet expensive antimalarial, has quickly become the recommended drug of choice when all other possibilities fail. However, for all its promise as the next great antimalarial, the outlook is bleak. Resistance is developing to artemisinin while another effective antimalarial is not in sight. Malaria endemic areas which are mostly in developing countries must deal with the multifaceted process of changing and implementing new national malaria treatment guidelines. This requires complex interactions between several sectors of the affected society which in some cases take place within the context of political instability. Moreover, the cost associated with preventing and containing the spread of antimalarial resistance is detrimental to economic progress. This review addresses the impact of artemisinin resistance on the socioeconomic structure of malaria endemic countries.Keywords: artemisinin-based drugs, social, economic, malarial parasite resistance

  3. The Power of Transformation: Wind, Sun and the Economics of Flexible Power Systems

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-03-01

    Wind power and solar photovoltaics (PV) are crucial to meeting future energy needs while decarbonising the power sector. Deployment of both technologies has expanded rapidly in recent years, one of the few bright spots in an otherwise bleak picture of clean energy progress. However, the inherent variability of wind power and solar PV raises unique and pressing questions. Can power systems remain reliable and cost-effective while supporting high shares of variable renewable energy (VRE)? And if so, how? Based on a thorough review of the integration challenge, this publication gauges the economic significance of VRE integration impacts; highlights the need for a system-wide approach to integrating high shares of VRE; and recommends how to achieve a cost-effective transformation of the power system. This book summarises the results of the third phase of the Grid Integration of VRE (GIVAR) project, undertaken by the IEA over the past two years. It is rooted in a set of seven case studies, comprising 15 countries on four continents. It deepens the technical analysis of previous IEA work and lays out an analytical framework for understanding the economics of VRE integration impacts. Based on detailed modelling, the impact of high shares of VRE on total system costs is analysed. In addition, the four flexible resources which are available to facilitate VRE integration - generation, grid infrastructure, storage and demand side integration - are assessed in terms of their technical performance and cost-effectiveness.

  4. Beyond Money: Progress on an Economy of Well-Being.

    Science.gov (United States)

    Diener, Ed; Seligman, Martin E P

    2018-03-01

    In our 2004 "Beyond Money" article, we argued that national accounts of psychological and subjective well-being should complement the economic indicators that frequently guide policy decisions. We claimed that economic indicators fail to reflect important aspects of quality of life that well-being indicators capture. Since the time of our article, progress has been made, and scores of nations have used some forms of well-being measures. The National Academy of Sciences of the United States and the Organization for Economic Cooperation and Development both issued reports on accounts of well-being. Researchers have pointed to policies that are supported by the findings, such as environmental and economic policies. The emergence of "big data" has opened major new pathways for measuring well-being in inexpensive, unobtrusive, and nonreactive fashion. Psychological researchers now need to create superordinate combinations of subjective and objective measures of well-being to study the impact of the policies they advocate. The accounts can serve as a lever for convincing policymakers to enact policies that increase human flourishing.

  5. ANALISIS PENETAPAN SEKTOR BASIS DAN DAMPAKNYA TERHADAP PERTUMBUHAN EKONOMI DI KABUPATEN BONE

    Directory of Open Access Journals (Sweden)

    Edi Cahyang

    2017-06-01

    The sector that has several advantages (four and three excellence such as Mining and quarrying sector which has a rapid growth at the provincial level, competitiveness / competitive, and included in the progressive growth (forward. Procurement Electricity and gas sector has a comparative advantage, rapid growth at the provincial level, and included in the category of progressive growth as well as in the sector, a local basis. Then the Wholesale and Retail sector has a comparative advantage, competitiveness, economic growth rate faster than the provincial and progressive growth or progress. With the advantages possessed hence these sectors can be considered as potential sectors to be developed in Bone regency.

  6. Progressive taxation as a tool for providing the budget system stability

    Directory of Open Access Journals (Sweden)

    Margarita A. Vakhtina

    2016-01-01

    Full Text Available Objective to consider the alternative additional sources of income of the state budget in the framework of the action plan of the Russian government to provide socioeconomic stability of the country in 2016. Methods comparative and dynamic analysis classification and typology description and measurements including using the tools of institutional Economics the data were interpreted using tables. Results it is shown that due to the lack of financial resources the government has to make unpopular decisions that reduce the level of social support of the population for the near future. The adopted laws stipulating the principles of address character and needs when providing regional measures of social support increase the risks of poverty and inequality. The analysis has been made of the ranking position of Russia and member countries of the Organization for Economic Cooperation and Development in terms of GDP per capita human development index and quality of life index. The article grounds the need for institutional change to facilitate transition to progressive taxation and redistribution of the tax burden from the poor and middle classes to the super rich. The flat personal income tax rate has not led to the desired results of growing tax revenues in the budget. Russia is still among the top ten states with the largest tax evasion losses. The weak redistributive mechanisms including a flat scale of personal income tax regressive social security contributions and low property taxes lead to stagnation inequality underfunding of education and health. Scientific novelty the article proves the conclusion about need of institutional transformations associated with changing the current tax policy priorities. The transition to a progressive scale of income and wealth taxation promotes the transfer of tax burden from the middle and poor to the rich. These measures can provide a double economic effect. On the one hand the principle of effective taxation

  7. Analysis of world economic variables using multidimensional scaling.

    Directory of Open Access Journals (Sweden)

    J A Tenreiro Machado

    Full Text Available Waves of globalization reflect the historical technical progress and modern economic growth. The dynamics of this process are here approached using the multidimensional scaling (MDS methodology to analyze the evolution of GDP per capita, international trade openness, life expectancy, and education tertiary enrollment in 14 countries. MDS provides the appropriate theoretical concepts and the exact mathematical tools to describe the joint evolution of these indicators of economic growth, globalization, welfare and human development of the world economy from 1977 up to 2012. The polarization dance of countries enlightens the convergence paths, potential warfare and present-day rivalries in the global geopolitical scene.

  8. Effects of atmospheric variability on energy utilization and conservation. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    Reiter, E.R.; Burns, C.C.; Cochrane, H.; Johnson, G.R.; Leong, H.; Sheaffer, J.D.

    1980-07-01

    Research progress for the period September 1979 to July 1980 is reported. Research was structured along four major tasks: (1) atmospheric circulation and climate variability; (2) urban mesoclimate; (3) energy demand modelling; and (4) economic implications of weather variability and energy demand: stimulating residential energy conservation through the financial section. (ACR)

  9. The relation between Chinese economic development and energy consumption in the different periods

    International Nuclear Information System (INIS)

    Yuan Chaoqing; Liu Sifeng; Fang Zhigeng; Xie Naiming

    2010-01-01

    Since the 1980s, Chinese economy grew rapidly. With the rapid economic growth, Chinese energy consumption sharply increased. The relation between Chinese energy consumption and economic growth is focused on, and many researchers have studied this issue by applying the methods such as granger causality test. However, the results just reveal the relation in a very long period. In this paper, the history of Chinese economy is divided into four periods. And the relation between Chinese energy consumption and economic growth is examined by applying grey incidence analysis, which is one of the most important methods of grey system theory which can be applied to solve the problems with small samples. The results show that the relations in different periods are not the same. The degree of grey incidences between total energy consumption and values added of secondary industry is larger, and the degree of grey incidences between GDP and consumption of coal is larger too. And the policy implications of these results are explained.

  10. The relation between Chinese economic development and energy consumption in the different periods

    Energy Technology Data Exchange (ETDEWEB)

    Yuan Chaoqing, E-mail: yuanchaoqing@126.co [Economics and Management College, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Liu Sifeng; Fang Zhigeng; Xie Naiming [Economics and Management College, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China)

    2010-09-15

    Since the 1980s, Chinese economy grew rapidly. With the rapid economic growth, Chinese energy consumption sharply increased. The relation between Chinese energy consumption and economic growth is focused on, and many researchers have studied this issue by applying the methods such as granger causality test. However, the results just reveal the relation in a very long period. In this paper, the history of Chinese economy is divided into four periods. And the relation between Chinese energy consumption and economic growth is examined by applying grey incidence analysis, which is one of the most important methods of grey system theory which can be applied to solve the problems with small samples. The results show that the relations in different periods are not the same. The degree of grey incidences between total energy consumption and values added of secondary industry is larger, and the degree of grey incidences between GDP and consumption of coal is larger too. And the policy implications of these results are explained.

  11. The relation between Chinese economic development and energy consumption in the different periods

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Chaoqing; Liu, Sifeng; Fang, Zhigeng; Xie, Naiming [Economics and Management College, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China)

    2010-09-15

    Since the 1980s, Chinese economy grew rapidly. With the rapid economic growth, Chinese energy consumption sharply increased. The relation between Chinese energy consumption and economic growth is focused on, and many researchers have studied this issue by applying the methods such as granger causality test. However, the results just reveal the relation in a very long period. In this paper, the history of Chinese economy is divided into four periods. And the relation between Chinese energy consumption and economic growth is examined by applying grey incidence analysis, which is one of the most important methods of grey system theory which can be applied to solve the problems with small samples. The results show that the relations in different periods are not the same. The degree of grey incidences between total energy consumption and values added of secondary industry is larger, and the degree of grey incidences between GDP and consumption of coal is larger too. And the policy implications of these results are explained. (author)

  12. Age-Dependent Effects of Topiramate on the Acquisition and the Retention of Rapid Kindling

    Science.gov (United States)

    Mazarati, Andréy; Shin, Don; Auvin, Stéphane; Sankar, Raman

    2008-01-01

    Summary Purpose To examine antiepileptogenic, disease-modifying, and anticonvulsant effects of topiramate under conditions of rapid kindling at different stages of development. Methods Afterdischarge threshold (ADT) and duration (ADD) were examined in two-, three-, and five-week old Wistar rats before and after administration of topiramate (200 mg/kg). Animals underwent a rapid kindling protocol (sixty 10 second trains, bipolar 20 Hz square wave pulses delivered every five minutes). The progression of behavioral and electrographic seizures, and responses to test stimulations 24 hours after the protocol were compared between topiramate and vehicle treated control rats. In addition, rats that were previously given vehicle only prior to kindling, were then given topiramate to examine the effect on established kindled seizures. Results In two-week old animals, topiramate affected neither the baseline afterdischarge, nor the progression of kindled seizures. In three-week old rats, topiramate did not modify the baseline afterdischarge, but significantly delayed the occurrence of full motor seizures in response to repeated stimulations. Topiramate treatment of five-week old rats increased baseline ADT, shortened ADD, and delayed the progression of kindled seizures. Twenty four hours after the last kindling stimulation, animals of all ages exhibited a decreased ADT, an increase ADD, and developed behavioral seizures in response to threshold stimulation. Vehicle treated kindled rats that were then given topiramate displayed significantly attenuated behavioral seizures induced by the threshold stimulation. Conclusions Topiramate exhibited age-dependent disease-modifying effects under conditions of rapid kindling, but failed to block epileptogenesis. Topiramate also inhibited kindled seizures with equal efficacy across the three ages. PMID:17319916

  13. Savings, Investment & FDI Contribution To Malaysian Economic Growth In The Globalization Era

    OpenAIRE

    Kasim Mansur; Markos Mamalakis; Sidah Idris

    2011-01-01

    What are the prospects and future of Foreign Direct Investment (FDI) in Malaysia now? Malaysia is undoubtedly a development success story. Throughout the post-independence period since 1957, Malaysia has enjoyed rapid economic growth with rising per capita income and price stability. Rising living standards, greater urbanization and access to health and education, and an improvement in the distribution of income have accompanied economic growth. Malaysian performance has been particularly rem...

  14. Role of Diet and Nutritional Supplements in Parkinson’s Disease Progression

    Directory of Open Access Journals (Sweden)

    Laurie K. Mischley

    2017-01-01

    Full Text Available Objectives. The goal of this study is to describe modifiable lifestyle variables associated with reduced rate of Parkinson’s disease (PD progression. Methods. The patient-reported outcomes in PD (PRO-PD were used as the primary outcome measure, and a food frequency questionnaire (FFQ was used to assess dietary intake. In this cross-sectional analysis, regression analysis was performed on baseline data to identify the nutritional and pharmacological interventions associated with the rate of PD progression. All analyses were adjusted for age, gender, and years since diagnosis. Results. 1053 individuals with self-reported idiopathic PD were available for analysis. Foods associated with the reduced rate of PD progression included fresh vegetables, fresh fruit, nuts and seeds, nonfried fish, olive oil, wine, coconut oil, fresh herbs, and spices (P<0.05. Foods associated with more rapid PD progression include canned fruits and vegetables, diet and nondiet soda, fried foods, beef, ice cream, yogurt, and cheese (P<0.05. Nutritional supplements coenzyme Q10 and fish oil were associated with reduced PD progression (P=0.026 and P=0.019, resp., and iron supplementation was associated with faster progression (P=0.022. Discussion. These are the first data to provide evidence that targeted nutrition is associated with the rate of PD progression.

  15. Closing the Gaps: Health Equity Research Initiative in India | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    India's rapid economic progress has its costs. There has been a significant increase in social and economic inequalities by class, caste, ethnicity, gender, and location. ... Most of the studies fail to examine the combination of factors, pathways, and frameworks that influence how health equity issues are conceptualized, ...

  16. Information and communication technology use and economic growth.

    Science.gov (United States)

    Farhadi, Maryam; Ismail, Rahmah; Fooladi, Masood

    2012-01-01

    In recent years, progress in information and communication technology (ICT) has caused many structural changes such as reorganizing of economics, globalization, and trade extension, which leads to capital flows and enhancing information availability. Moreover, ICT plays a significant role in development of each economic sector, especially during liberalization process. Growth economists predict that economic growth is driven by investments in ICT. However, empirical studies on this issue have produced mixed results, regarding to different research methodology and geographical configuration of the study. This paper examines the impact of Information and Communication Technology (ICT) use on economic growth using the Generalized Method of Moments (GMM) estimator within the framework of a dynamic panel data approach and applies it to 159 countries over the period 2000 to 2009. The results indicate that there is a positive relationship between growth rate of real GDP per capita and ICT use index (as measured by the number of internet users, fixed broadband internet subscribers and the number of mobile subscription per 100 inhabitants). We also find that the effect of ICT use on economic growth is higher in high income group rather than other groups. This implies that if these countries seek to enhance their economic growth, they need to implement specific policies that facilitate ICT use.

  17. Information and communication technology use and economic growth.

    Directory of Open Access Journals (Sweden)

    Maryam Farhadi

    Full Text Available In recent years, progress in information and communication technology (ICT has caused many structural changes such as reorganizing of economics, globalization, and trade extension, which leads to capital flows and enhancing information availability. Moreover, ICT plays a significant role in development of each economic sector, especially during liberalization process. Growth economists predict that economic growth is driven by investments in ICT. However, empirical studies on this issue have produced mixed results, regarding to different research methodology and geographical configuration of the study. This paper examines the impact of Information and Communication Technology (ICT use on economic growth using the Generalized Method of Moments (GMM estimator within the framework of a dynamic panel data approach and applies it to 159 countries over the period 2000 to 2009. The results indicate that there is a positive relationship between growth rate of real GDP per capita and ICT use index (as measured by the number of internet users, fixed broadband internet subscribers and the number of mobile subscription per 100 inhabitants. We also find that the effect of ICT use on economic growth is higher in high income group rather than other groups. This implies that if these countries seek to enhance their economic growth, they need to implement specific policies that facilitate ICT use.

  18. Economic benefits of power factor correction at a nuclear facility

    International Nuclear Information System (INIS)

    Boger, R.M.; Dalos, W.; Juguilon, M.E.

    1986-01-01

    The economic benefits of correcting poor power factor at an operating nuclear facility are shown. A project approach for achieving rapid return of investment without disrupting plant availability is described. Examples of technical problems associated with using capacitors for power factor correction are presented

  19. Why Does Population Aging Matter So Much for Asia? Population Aging, Economic Growth, and Economic Security in Asia

    OpenAIRE

    Lee, Sang-Hyop; Mason, Andrew; Park, Donghyun

    2011-01-01

    Asia as a whole is experiencing a rapid demographic transition toward older populations, though different countries are at different stages of this region- wide trend. We document Asia's aging population, describe the region's old-age support systems, and highlight the regional socioeconomic implications of the transition for those support systems. Aging populations present two fundamental challenges to Asian policymakers: (1) developing socioeconomic systems that can provide economic securit...

  20. The Economic Causes and Consequences of Social Instability in China

    OpenAIRE

    John Knight

    2012-01-01

    Social instability is a concept that economists rarely analyse, and yet it can lurk behind much economic policy-making. China’s leadership has often publicly expressed its concerns to avoid ‘social instability’. It is viewed as a threat both to the political order and to the continued rapid growth of the economy. This threat to growth in turn endangers the maintenance of social stability. This paper examines the likely economic determinants of social instability, using both surveys and ...

  1. The main issues preventing Kosovo’s economic development

    Directory of Open Access Journals (Sweden)

    Demir Lima

    2017-11-01

    Full Text Available This study provides an analysis of several problematic factors preventing Kosovo’s economic development. Several sectors that could have been the main pillars of economic development, such as manufacturing, energy, mines and minerals, and other economic sectors have been neglected from the development by domestic institutions or were used clandestinely by certain interest groups, whose focus was not in the development of the country but rather their personal gain. Trade remained the preferred activity throughout these years, which cannot be considered a beneficial sector for economic development, as much as manufacturing, which remains to date as Kosovo’s most underdeveloped sector. As long as Kosovo’s exports cover only 12% of total imports, no economic growth can be expected. Kosovo’s failure to attract strategic investors in years, which could open new jobs, has also contributed its lack of sufficient economic development. Thus, the most concerning issue during this period is the decline in foreign direct investments, which were expected to increase after the declaration of independence. In the lack of a long-term development strategy for certain sectors or priority activities, such as mines, energy, industry etc., there is no progress in the country's economic development. The main issue is that we should only favor those activities or identify segments where we have competitive advantages compared to other countries.

  2. Soluble beta-amyloid precursor protein is related to disease progression in amyotrophic lateral sclerosis.

    Directory of Open Access Journals (Sweden)

    Petra Steinacker

    Full Text Available BACKGROUND: Biomarkers of disease progression in amyotrophic lateral sclerosis (ALS could support the identification of beneficial drugs in clinical trials. We aimed to test whether soluble fragments of beta-amyloid precursor protein (sAPPα and sAPPß correlated with clinical subtypes of ALS and were of prognostic value. METHODOLOGY/PRINCIPAL FINDINGS: In a cross-sectional study including patients with ALS (N = 68 with clinical follow-up data over 6 months, Parkinson's disease (PD, N = 20, and age-matched controls (N = 40, cerebrospinal fluid (CSF levels of sAPPα a, sAPPß and neurofilaments (NfH(SMI35 were measured by multiplex assay, Progranulin by ELISA. CSF sAPPα and sAPPß levels were lower in ALS with a rapidly-progressive disease course (p = 0.03, and p = 0.02 and with longer disease duration (p = 0.01 and p = 0.01, respectively. CSF NfH(SMI35 was elevated in ALS compared to PD and controls, with highest concentrations found in patients with rapid disease progression (p<0.01. High CSF NfH(SMI3 was linked to low CSF sAPPα and sAPPß (p = 0.001, and p = 0.007, respectively. The ratios CSF NfH(SMI35/CSF sAPPα,-ß were elevated in patients with fast progression of disease (p = 0.002 each. CSF Progranulin decreased with ongoing disease (p = 0.04. CONCLUSIONS: This study provides new CSF candidate markers associated with progression of disease in ALS. The data suggest that a deficiency of cellular neuroprotective mechanisms (decrease of sAPP is linked to progressive neuro-axonal damage (increase of NfH(SMI35 and to progression of disease.

  3. PUBLIC SECTOR - CONCEPTUAL ELEMENTS, IMPLICATIONS IN ECONOMIC AND SOCIAL LIFE

    Directory of Open Access Journals (Sweden)

    Florina Popa

    2017-07-01

    Full Text Available The public economy, branch of economic science analyses the state, as economic actor; its field of research interacts with investigations of other areas of economic science (monetary, international trade, market organization etc.. The state has experienced various stages of manifestation of its role in the economy, against the changes in society, which led to either an increase in its intervention, to regulate market phenomena, the recovery of economic activity in times of crisis, or to its decline against the modernization of the economies of industrialized countries, the increase of the role of entrepreneurs, technological progress. Thus, the development of economic science, changes in economic area, the emergence of capitalism, of industrialization in the nineteenth century, especially the second half, outlined a new role towards state intervention in economic life; in the context of new economic developments of the last decades of the twentieth century, the interventionist role of the state has diminished, the state giving up certain activities, in return for initiating other actions (privatization, reducing state monopoly, deregulation.nThe paper presents conceptual elements referring to public sector, peculiarities that distinguish it from the private sector, as well as issues about the state implication in the economic life, in different periods of evolution of society.

  4. Relationship between Admission Selection Criteria and Academic Progression for Student Nurse Anesthetists

    Science.gov (United States)

    Burns, Sharon M.

    2009-01-01

    Today's admission selection criteria require refinement with the intention of fostering academic progression for students entering nurse anesthesia programs (Reese, 2002).With the escalating cost of graduate education coupled with the current economic crisis, efforts by educational leaders to minimize attrition remains pivotal (Andrews, Johansson,…

  5. Current research on progressive familial intrahepatic cholestasis

    Directory of Open Access Journals (Sweden)

    DENG Baocheng

    2015-09-01

    Full Text Available Progressive familial intrahepatic cholestasis (PFIC refers to a heterogeneous group of autosomal-recessive disorders. The estimated incidence varies between 1/50,000 and 1/100,000 births. Three types of PFIC have been identified and related to mutations in hepatocellular transport system genes involved in bile formation. PFIC-1, PFIC-2, and PFIC-3 are due to mutations in ATP8B1, ABCB11, and ABCB4 genes involved in bile secretion, respectively. Serum gamma-glutamyl transpeptidase is normal in patients with PFIC-1 and PFIC-2, while it is raised in patients with PFIC3. The main clinical manifestation of PFIC is severe intrahepatic cholestasis. PFIC usually appears in infancy or childhood and rapidly progresses to end-stage liver disease before adulthood. Diagnosis of this disease is based on clinical manifestations, liver function tests, liver ultrasonography, liver histology, and genetic testing. Ursodeoxycholic acid therapy is the initial treatment in all PFIC patients to prevent liver damage. In some PFIC1 and PFIC2 patients, biliary diversion may also relieve pruritus and slow disease progression. However, most PFIC patients are ultimately candidates for liver transplantation.

  6. Progress in ISOL target-ion source systems

    Energy Technology Data Exchange (ETDEWEB)

    Koester, U. [Institut Laue Langevin, 6 Rue Jules Horowitz, F-38042 Grenoble Cedex 9 (France); ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland)], E-mail: koester@ill.fr; Arndt, O. [HGF VISTARS and Institut fuer Kernchemie, Johannes-Gutenberg Universitaet Mainz, D-55128 Mainz (Germany); Bouquerel, E.; Fedoseyev, V.N. [ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland); Franberg, H. [ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland); Laboratory for Radio- and Environmental Chemistry, Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Joinet, A. [ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland); Centre d' Etude Spatiale des Rayonnements, 9 Av. du Colonel Roche, F-31028 Toulouse Cedex 4 (France); Jost, C. [HGF VISTARS and Institut fuer Kernchemie, Johannes-Gutenberg Universitaet Mainz, D-55128 Mainz (Germany); Kerkines, I.S.K. [Laboratory of Physical Chemistry, National and Kapodistrian University of Athens, Department of Chemistry, Zografou 157 71, GR (Greece); Cherry L. Emerson Center for Scientific Computation and Department of Chemistry, Emory University, Atlanta, GA 30322 (United States); Kirchner, R. [Gesellschaft fuer Schwerionenforschung, Planckstr. 1, D-64291 Darmstadt (Germany)

    2008-10-15

    The heart of every ISOL (isotope separation on-line) facility is its target and ion source system. Its efficiency, selectivity and rapidity is decisive for the production of intense and pure ion beams of short-lived isotopes. Recent progress in ISOL target and ion source technology is discussed at the examples of radioactive ion beams of exotic zinc and tin isotopes that were purified by isothermal chromatography and molecular sideband separation respectively. An outlook is given to which other elements these purification methods are applicable.

  7. Progress in ISOL target-ion source systems

    International Nuclear Information System (INIS)

    Koester, U.; Arndt, O.; Bouquerel, E.; Fedoseyev, V.N.; Franberg, H.; Joinet, A.; Jost, C.; Kerkines, I.S.K.; Kirchner, R.

    2008-01-01

    The heart of every ISOL (isotope separation on-line) facility is its target and ion source system. Its efficiency, selectivity and rapidity is decisive for the production of intense and pure ion beams of short-lived isotopes. Recent progress in ISOL target and ion source technology is discussed at the examples of radioactive ion beams of exotic zinc and tin isotopes that were purified by isothermal chromatography and molecular sideband separation respectively. An outlook is given to which other elements these purification methods are applicable.

  8. Integrating global socio-economic influences into a regional land use change model for China

    Science.gov (United States)

    Xu, Xia; Gao, Qiong; Peng, Changhui; Cui, Xuefeng; Liu, Yinghui; Jiang, Li

    2014-03-01

    With rapid economic development and urbanization, land use in China has experienced huge changes in recent years; and this will probably continue in the future. Land use problems in China are urgent and need further study. Rapid land-use change and economic development make China an ideal region for integrated land use change studies, particularly the examination of multiple factors and global-regional interactions in the context of global economic integration. This paper presents an integrated modeling approach to examine the impact of global socio-economic processes on land use changes at a regional scale. We develop an integrated model system by coupling a simple global socio-economic model (GLOBFOOD) and regional spatial allocation model (CLUE). The model system is illustrated with an application to land use in China. For a given climate change, population growth, and various socio-economic situations, a global socio-economic model simulates the impact of global market and economy on land use, and quantifies changes of different land use types. The land use spatial distribution model decides the type of land use most appropriate in each spatial grid by employing a weighted suitability index, derived from expert knowledge about the ecosystem state and site conditions. A series of model simulations will be conducted and analyzed to demonstrate the ability of the integrated model to link global socioeconomic factors with regional land use changes in China. The results allow an exploration of the future dynamics of land use and landscapes in China.

  9. Analyzing suitability for urban expansion under rapid coastal urbanization with remote sensing and GIS techniques: a case study of Linanyungang, China

    DEFF Research Database (Denmark)

    Zhao, Wenjun; Zhu, Xiaodong; Reenberg, Anette

    2010-01-01

    Beginning in 2000, Lianyungang's urbanization entered a period of rapid growth, spatially as well as economically. Rapid and intensive expansion of "construction land" imposed increasing pressures on regional environment. With the support of remote sensing data and GIS tools, this paper reports a...

  10. STYLIZED ECONOMIC FACTS OF TRANSITION

    Directory of Open Access Journals (Sweden)

    NATASHA TRAJKOVA-NAJDOVSKA

    2017-12-01

    Full Text Available In the course of transition, former socialistic countries moved from planned to market economy. This journey typically started with sharp falls in economic activity in all transition countries, accompanied by deterioration of various social indicators. Hence, their main objective was the recovery of economic activity, i.e. increasing the economic growth rate, which in addition was supposed to enable catching up with the European developed economies. This growth movement is usually described by famous U-curve of transition. However, in spite of the efforts and reforms, all transition economies recorded various paces of recovery. This study discusses that difference, through various GDP indicators, - real GDP path, GDP growth rates path, the height of the GDP index achieved and the volatility of growth rates. Analysed in concert, these indicators suggest several other variations of the transition Ucurve, such as: the rapid-J group, the wide-U group and the L-curve group. Namely, almost three decades after the start of the transition, the differences persist, suggesting that some transition economies has not moved significantly towards catching up with the successful transition countries, or with the developed economies.

  11. Using Level 1 E-Learning to Support Socio-Economic Development

    Science.gov (United States)

    Edmundson, Andrea

    2007-01-01

    The most developed, progressive, and economically stable countries in the world are those that are technologically advanced. Technological change and the building of human capabilities are interrelated: each requires the development of the other for success and the "rethinking [of] educational systems to meet the new challenges of…

  12. Spatial Pattern of Residential Carbon Dioxide Emissions in a Rapidly Urbanizing Chinese City and Its Mismatch Effect

    Directory of Open Access Journals (Sweden)

    Heli Lu

    2018-03-01

    Full Text Available Cities undergoing rapid urbanization are characterized by quick successions of spatiotemporal patterns, meaning that traditional methods cannot adequately assess carbon emissions from urban residential areas, which prevents the study of spatial mismatch. Therefore, this study utilizes night-time lights to construct a spatial emissions model that enables the analysis of the evolution of emissions patterns in China. The results indicate that, compared to the traditional method, the spatial modeling based on night-time lights reflects the spatial emissions trajectories in a more timely and accurate manner in rapidly urbanizing cities. Additionally, we found a relatively low degree of spatial match between emissions and economic activities, with the former, which are greatly affected by urbanization, having a larger dynamism and instability than the latter. Such spatial mismatch effect illustrates that policy makers should focus on factors beyond economics in order to reduce residential carbon emissions during China’s rapid urbanization process.

  13. Malaysia Economic Monitor, December 2017 : Turmoil to Transformation, 20 Years after the Asian Financial Crisis

    OpenAIRE

    World Bank Group

    2017-01-01

    The aim of the Malaysia Economic Monitor (MEM) is to foster better-informed policy analysis and debate regarding the key challenges that Malaysia faces in its endeavor to achieve rapid, inclusive and sustainable economic growth. The MEM consists of two parts: Part 1 presents a review of recent economic developments and a macroeconomic outlook. Part 2 focuses on a selected special topic that is key to Malaysia’s development prospects, particularly as the country move...

  14. Current State of Economic Returns from Education in China's Ethnic Regions and Explorations into Ways of Improvement

    Science.gov (United States)

    Lijun, Zhang; Fei, Wang

    2010-01-01

    Economic development and social progress in China's ethnic minority regions depend on improvements in population attributes brought about by education. Developing education in China's ethnic regions is a project of fundamental significance for realizing sustainable economic and social development in the ethnic regions. Improving the economic…

  15. Light ion ignitors for inertial confinement fusion: progress toward proof-of-principle

    International Nuclear Information System (INIS)

    Quintenz, J.P.; Kuswa, G.W.

    1981-01-01

    From the inception of the REB effort, it was recognized that light ion beams offered substantial advantages as an ICF driver, and as the pulse power driver program progressed the possibilities of using light ion beams became increasingly evident. Because of the rapid progress made in the available power in these light ion beams, their superior target deposition characteristics, the fact that nonrelativistic ion beams can readily be bunched by a factor of 2 to 4, and the favorable scaling relations leading toward reactor levels, Sandia shifted its ICF emphasis from electrons to ions in 1979. The progress which has been made toward proof-of-principle using light ion ignitors, as well as the remaining problems, will be detailed in this paper

  16. Methodological developments in US state-level Genuine Progress Indicators: toward GPI 2.0

    Science.gov (United States)

    Bagstad, Kenneth J.; Berik, Günseli; Gaddis, Erica J. Brown

    2014-01-01

    The Genuine Progress Indicator (GPI) has emerged as an important monetary measure of economic well-being. Unlike mainstream economic indicators, primarily Gross Domestic Product (GDP), the GPI accounts for both the benefits and costs of economic production across diverse economic, social, and environmental domains in a more comprehensive manner. Recently, the GPI has gained traction in subnational policy in the United States, with GPI studies being conducted in a number of states and with their formal adoption by several state governments. As the GPI is applied in different locations, new methods are developed, different data sources are available, and new issues of policy relevance are addressed using its component indicators. This has led to a divergence in methods, reducing comparability between studies and yielding results that are of varying methodological sophistication. In this study, we review the “state of the art” in recent US state-level GPI studies, focusing on those from Hawaii, Maryland, Ohio, Utah, and Vermont. Through adoption of a consistent approach, these and future GPI studies could utilize a framework that supports more uniform, comparable, and accurate measurements of progress. We also identify longer-term issues, particularly related to treatment of nonrenewable resource depletion, government spending, income inequality, and ecosystem services. As these issues are successfully addressed and disseminated, a “GPI 2.0” will emerge that better measures economic well-being and has greater accuracy and policy relevance than past GPI measurements. As the GPI expands further into mainstream policy analysis, a more formal process by which methods could be updated, standardized, and applied is needed.

  17. Economic growth of the United States: perspective and prospective. [Monograph

    Energy Technology Data Exchange (ETDEWEB)

    Fabricant, S

    1979-01-01

    A post-World War II analysis of the potential for US economic expansion projects a continuation of the basic social and economic expectations and international relations and of the upward trend of labor input, labor productivity, and national output. How economic growth of the future will differ as a result of global changes in population and resources is examined in the context of other national objectives. The rapid increase in labor productivity during the postwar period was taken in the form of income rather than leisure. This led to a growth of goods and real per capita income as well as higher standards of living, education, and economic stability. The implications for future growth indicate the need to slow the growth of the national product in line with the rate of population growth. The improved welfare of the people should be the overall goal of which economic growth is one component. 23 tables. (DCK)

  18. The Impact of Foreign Direct Investments on Economic Growth in Romania

    Directory of Open Access Journals (Sweden)

    Adrian Petre

    2015-12-01

    Full Text Available One of the current priority objectives for Romania is the integration into euro zone. To achieve this objective, Romania must record progress on economic growth. Various empirical studies have analyzed the influence of foreign direct investment (FDI on economic growth to see whether investment flows positively influence the economic development. The results revealed that positive connection depends on certain features of the economy at a time. The purpose of this research is to highlight the impact of the FDIs on the Romanian economic development because the debates on capital flows, both in the political and academic environment, associate these flows with a number of benefits for beneficiary states. In order to fulfill the objective of this research is analyzed, mainly, the relationship between foreign direct investment (FDI and gross domestic product (GDP.

  19. Social Wealth Economic Indicators for a Caring Economy

    Directory of Open Access Journals (Sweden)

    Indradeep Ghosh

    2015-06-01

    Full Text Available This essay introduces the reader to an entirely new set of measures that are urgently needed by policymakers and business leaders to foster personal, business, and national economic success. Social Wealth Economic Indicators are measures suggested by a partnership model of society, and they inform us that care work matters tremendously but is grossly undervalued. In our contemporary knowledge-service economy, the essential ingredient for social and economic progress is high-quality human capital, and the way to build such human capital is to support the work of caring and caregiving, traditionally considered “women’s work.” The data presented in this essay clearly show that early childhood care and education, family-friendly workplace practices, and the status of women are key determinants of economic success. But they are also necessary for healthy, creative, and cohesive societies in which members work in partnership with each other and with the natural environment to improve living conditions for all. This is the true meaning of social wealth.

  20. Recent progress in ERCP for biliary and pancreatic diseases

    Directory of Open Access Journals (Sweden)

    MIAO Lin

    2014-12-01

    Full Text Available In recent years, with the continuous development of endoscopic and interventional techniques, many new devices and methods have been used in clinical practice, and the application of endoscopic retrograde cholangiopancreatography (ERCP in biliary and pancreatic diseases has developed rapidly. This paper reviews and summarizes the recent progress in ERCP among patients with biliary and pancreatic diseases, including those with altered gastrointestinal anatomy, pregnant patients, patients with benign and malignant biliary strictures, and patients with pancreatic pseudocysts, as well as the application of SpyGlass, photodynamic therapy, and radiofrequency ablation, the management of ERCP-related duodenal perforation, and the prevention of post-ERCP pancreatitis. All the progress has made a great contribution to the diagnosis and treatment of biliary and pancreatic diseases.

  1. Two-step rapid sulfur capture. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-04-01

    The primary goal of this program was to test the technical and economic feasibility of a novel dry sorbent injection process called the Two-Step Rapid Sulfur Capture process for several advanced coal utilization systems. The Two-Step Rapid Sulfur Capture process consists of limestone activation in a high temperature auxiliary burner for short times followed by sorbent quenching in a lower temperature sulfur containing coal combustion gas. The Two-Step Rapid Sulfur Capture process is based on the Non-Equilibrium Sulfur Capture process developed by the Energy Technology Office of Textron Defense Systems (ETO/TDS). Based on the Non-Equilibrium Sulfur Capture studies the range of conditions for optimum sorbent activation were thought to be: activation temperature > 2,200 K for activation times in the range of 10--30 ms. Therefore, the aim of the Two-Step process is to create a very active sorbent (under conditions similar to the bomb reactor) and complete the sulfur reaction under thermodynamically favorable conditions. A flow facility was designed and assembled to simulate the temperature, time, stoichiometry, and sulfur gas concentration prevalent in the advanced coal utilization systems such as gasifiers, fluidized bed combustors, mixed-metal oxide desulfurization systems, diesel engines, and gas turbines.

  2. Big Social Network Data and Sustainable Economic Development

    Directory of Open Access Journals (Sweden)

    Umit Can

    2017-11-01

    Full Text Available New information technologies have led to the rapid and effective growth of social networks. The amount of data produced by social networks has increased the value of the big data concept, which is one of the popular current phenomena. The immediate or unpredictable effects of a wide array of economic activities on large masses and the reactions to them can be measured by using social media platforms and big data methods. Thus, it would be extremely beneficial to analyze the harmful environmental and social impacts that are caused by unsustainable business applications. As social networks and big data are popular realms currently, their efficient use would be an important factor in sustainable economic development. Accurate analysis of people’s consumption habits and economic tendencies would provide significant advantages to companies. Moreover, unknown consumption factors that affect the economic preferences of individuals can be discovered and economic efficiency can be increased. This study shows that the numerous solution opportunities that are provided by social networks and big data have become significant tools in dynamic policy creation by companies and states, in solving problems related to women’s rights, the environment, and health.

  3. Working through resistance in engaging boys and men towards gender equality and progressive masculinities

    Science.gov (United States)

    Ratele, Kopano

    2015-01-01

    Over the last two decades, a focus on challenging and transforming dominant forms of masculinity and engaging boys and men towards gender equality and healthy masculinities has permeated South African social and health sciences and the humanities. This focus on men and boys has also been evident in intervention and activist work. However, the turn to boys, men and masculinities has not gone without resistance, contestation and contradictions. A range of localised and global realities has frustrated much of the enthusiasm for rapid, sweeping and concrete changes regarding gender justice and the making of progressive masculinities. Among the discursive and material forces that oppose work that engages boys and men are those to do with income-related issues, race and racism, cultural traditions and gender itself. Because of this, it is contended that engagement with boys and men needs to consider not only gender but also economic inequality, poverty and unemployment, divisions created by race, and struggles around tradition. This paper discusses these forces that undermine and counteract work with boys and men and how we might work through resistance in engaging with men and boys. PMID:26073936

  4. Working through resistance in engaging boys and men towards gender equality and progressive masculinities.

    Science.gov (United States)

    Ratele, Kopano

    2015-01-01

    Over the last two decades, a focus on challenging and transforming dominant forms of masculinity and engaging boys and men towards gender equality and healthy masculinities has permeated South African social and health sciences and the humanities. This focus on men and boys has also been evident in intervention and activist work. However, the turn to boys, men and masculinities has not gone without resistance, contestation and contradictions. A range of localised and global realities has frustrated much of the enthusiasm for rapid, sweeping and concrete changes regarding gender justice and the making of progressive masculinities. Among the discursive and material forces that oppose work that engages boys and men are those to do with income-related issues, race and racism, cultural traditions and gender itself. Because of this, it is contended that engagement with boys and men needs to consider not only gender but also economic inequality, poverty and unemployment, divisions created by race, and struggles around tradition. This paper discusses these forces that undermine and counteract work with boys and men and how we might work through resistance in engaging with men and boys.

  5. Economic benefits analysis of listed companies in radiation processing

    International Nuclear Information System (INIS)

    Zhang Yingming; Xu Tao; Zhang Yue; Yang Bin; Zhao Wenying

    2012-01-01

    Radiation processing industry is an important part of civilian nuclear technology and develop rapidly during the past decade. Radiation modification of new materials industries use new technology to promote new product development and application and get good economic benefit. There are problems and bottlenecks during the development, such as how to implement the guideline of optimize the industrial structure and upgrade the product, and adapt the market develop law and need. By analysing the typical listed companies in this field together with the domestic economic development condition and future situation, we give the development strategy and method in the future. (authors)

  6. Economic Benefit of Introducing a Bus Rapid Transit (BRT) in Kano State Nigeria

    Science.gov (United States)

    Ahmad, K. A.; Afolabi, S.; Nda, M.; Daura, H. A.

    2018-04-01

    The objective of this study is to know the variables use in quantifying economic benefits of public transport project, contribution of public transport to economic productivity This paper attempts to provide a Road User Cost (RUC) comparison of current usage of Buses and Cars in three different stages which are the present time, do nothing and the introduction of new modes. Vehicle operating cost (VOC), value of time (VOT), pollution cost, accident cost and environmental cost are calculated in other to know the benefits for their abilities to ensure accessibility and mobility, reduce accidents and reduce environmental loss. The study stretch involves an 11.1 km of 2-lane divided carriageway road connecting Kabuga bus stop to Janguza market. Social costs which included accident costs, accident cost of cars (private modes) were found to be 50 times the accident cost of bus accidents. California Air Resource Board (CARB) model was adopted to evaluate Environmental costs. The total road user costs were then obtained to provide comparative evaluation among the study modes. Furthermore, the multiple future scenarios were created to provide understanding about the need for inclusion of other modes. In this regard, this paper provided a framework for the cost evaluation for an urban area and results indicate that buses are more cost-effective in transportation of equivalent number of passengers.

  7. The dynamics of oil consumption and economic growth in Malaysia

    International Nuclear Information System (INIS)

    Park, Sun-Young; Yoo, Seung-Hoon

    2014-01-01

    This study attemps to investiagte the causal relationship between oil consumption and economic growth in Malaysia where oil consumption and real gross domestic product have been rapidly increased in recent years. To this end, the study employs annual data covering the period 1965–2011. Tests for unit roots, co-integration, and Granger-causality based on the error-correction models are presented. The overall results support the existence of bi-directional causality between oil consumption and economic growth in Malaysia. This means that an increase in oil consumption directly affect economic growth. Thus, in order not to make an adverse effect on economic growth, Malaysia should endeavor to overcome the constraints on oil consumption. Moreover, it appears that economic growth induces oil consumption. - Highlights: • We examine the causality between oil consumption and economic growth in Malaysia. • We employed the annual data covering the period 1965–2011. • We estimated error-correction models to test for the direction of causality. • We found that there is bi-directional causality between the two

  8. Progressive outer retinal necrosis: manifestation of human immunodeficiency virus infection.

    Science.gov (United States)

    Lo, Phey Feng; Lim, Rongxuan; Antonakis, Serafeim N; Almeida, Goncalo C

    2015-05-06

    We present the case of a 54-year-old man who developed progressive outer retinal necrosis (PORN) as an initial manifestation of HIV infection without any significant risk factors for infection with HIV. PORN is usually found as a manifestation of known AIDS late in the disease. Our patient presented with transient visual loss followed by decrease in visual acuity and facial rash. Subsequent investigation revealed anterior chamber tap positive for varicella zoster virus (VZV), as well as HIV positivity, with an initial CD4 count of 48 cells/µL. Systemic and intravitreal antivirals against VZV, and highly active antiretroviral therapy against HIV were started, which halted further progression of retinal necrosis. This case highlights the importance of suspecting PORN where there is a rapidly progressive retinitis, and also testing the patient for HIV, so appropriate treatment can be started. 2015 BMJ Publishing Group Ltd.

  9. European food and nutrition policies in action. Finland's food and nutrition policy: progress, problems and recommendations.

    Science.gov (United States)

    Milio, N

    1998-01-01

    , where listening to the consumer (whether an individual, retailer or caterer) may not necessarily result in healthier products are more accurate consumer information, especially as foreign products and media continue to attract Finnish young people. The lack of a leading strategic body that can authoritatively assess and anticipate problems in implementation, deal with them and coordinate and monitor the necessary action in fundamental to these issues. Rapid progress in economic and farm policy development and food enterprises can provide conditions supportive of health and nutrition goals if such interests are systematically taken into account and allowed to moderate potential negative changes. If it is to be effective, such accounting will require initiative, clarity of strategic purpose and organization by health and nutrition leaders.

  10. The Employment Impact of Poland’s Special Economic Zones Policy

    DEFF Research Database (Denmark)

    Jensen, Camilla

    2018-01-01

    >gminas (communes) more likely to be negatively affected by the economic transition. A significant and positive effect of the policy on employment is documented, but with some negative spillovers at the policy level as zones start to spread rapidly. Accounting for covariates, timing, policy spillovers and reducing......In 1994, Poland launched a special economic zones experiment to maintain employment structures outside the major cities. Using difference-in-difference estimations, this paper evaluates whether the policy has been successful in its primary objective, which is to sustain employment in

  11. [Specificities of the logopenic variant of primary progressive aphasia].

    Science.gov (United States)

    Magnin, E; Teichmann, M; Martinaud, O; Moreaud, O; Ryff, I; Belliard, S; Pariente, J; Moulin, T; Vandel, P; Démonet, J-F

    2015-01-01

    The logopenic variant of primary progressive aphasia is a syndrome with neuropsychological and linguistic specificities, including phonological loop impairment for which diagnosis is currently mainly based on the exclusion of the two other variants, semantic and nonfluent/agrammatic primary progressive aphasia. The syndrome may be underdiagnosed due (1) to mild language difficulties during the early stages of the disease or (2) to being mistaken for mild cognitive impairment or Alzheimer's disease when the evaluation of episodic memory is based on verbal material and (3) finally, it is not uncommon that the disorders are attributed to psychiatric co-morbidities such as, for example, anxiety. Moreover, compared to other variants of primary progressive aphasia, brain abnormalities are different. The left temporoparietal junction is initially affected. Neuropathology and biomarkers (cerebrospinal fluid, molecular amyloid nuclear imaging) frequently reveal Alzheimer's disease. Consequently this variant of primary progressive aphasia does not fall under the traditional concept of frontotemporal lobar degeneration. These distinctive features highlight the utility of correct diagnosis, classification, and use of biomarkers to show the neuropathological processes underlying logopenic primary progressive aphasia. The logopenic variant of primary progressive aphasia is a specific form of Alzheimer's disease frequently presenting a rapid decline; specific linguistic therapies are needed. Further investigation of this syndrome is needed to refine screening, improve diagnostic criteria and better understand the epidemiology and the biological mechanisms involved. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  12. A hermeneutic science: health economics and Habermas.

    Science.gov (United States)

    Small, Neil; Mannion, Russell

    2005-01-01

    Mainstream health economics labours under a misleading understanding of the nature of the topic area and suffers from a concomitant poverty of thinking about theory and method. The purpose here is to explore this critical position and argue that health economics should aspire to being more than a technical discipline. It can, and should, engage with transformative discourse. It is argued that the hermeneutic sciences, emphasising interpretation not instrumentality or domination, offer a route into the change to which one seeks to contribute. The article specifically focuses on the way Habermas provides insights in his approach to knowledge, reason and political economy. How he emphasises complexity and interaction within cultural milieu is explored and primacy is given to preserving the life-world against the encroachments of a narrow rationalization. The argument for a critical re-imagining of health economics is presented in three stages. First, the antecedents, current assumptions and critical voices from contemporary economics and health economics are reviewed. Second, the way in which health is best understood via engaging with the complexity of both the subject itself and the society and culture within which it is embedded is explored. Third, the contribution that hermeneutics, and Habermas' critical theory, could make to a new health economics is examined. The paper offers a radical alternative to health economics. It explores the shortcomings of current thinking and argues an optimistic position. Progress via reason is possible if one reframes both in the direction of communication and in the appreciation of reflexivity and communality. This is a position that resonates with many who challenge prevailing paradigms, in economics and elsewhere.

  13. Economic Imagination and Support For Parliamentary Democracy In Poland

    Directory of Open Access Journals (Sweden)

    Andrzej K. Koźmiński

    2014-06-01

    Full Text Available Purpose: The article introduces a concept of the economic imagination, describes economic public attitudes and discusses the character of the contemporary economic imagination of Poles. Methodology: Representative survey conducted on the stratifi ed random sample of 1022 adult respondents by means of CAPI (computer assisted personal interview. Statistical analysis of data. Findings: The features perceived by public as economically benefi cial to the entire economy, particular enterprises and individuals have been ranked by the representative survey and statistically grouped into more general clusters. Those considered as good for the economy are grouped into such factors as “investment and competition”, “statism (etatism” and “progressive taxation”. The features considered as benefi cial for the enterprises are grouped into “human, social and economic capital”, “law obedience and good social relations” and “limited free market”. Personal characteristics perceived as benefi cial for individual’s economic success are grouped into “honesty, perseverance and good social relations”, “skills and diligence” and “nepotism and instrumentalism”. Intensity as well as determinants of such general value loaded convictions, and their impact on acceptance of democracy have been revealed as well. The implications: Economic imagination has to be analysed as an important factor of socio-economic system’s legitimization. Originality: Distinction and empirical defi nition of economic attitudinal syndromes at three different levels: macro-economic, enterprise and individual constitute a novelty in socio-economic research. Discussion of their determinants and wider implications constitute a new contribution to the theory of social legitimization.

  14. 2003 Stewardship progress report : committed to continuous improvement

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-12-01

    The stewardship initiative is a mandatory requirement for members of the Canadian Association of Petroleum Producers (CAPP). It involves performance management and benchmarking, voluntary audits and verification, as well as training and improved communication inside and outside the industry. This fourth annual progress report describes the environment, health, safety and socio-economic stewardship initiative. This report presents an aggregate of industry performance. Stewardship of Excellence awards were presented in 2003, celebrating outstanding performance by members who demonstrated their commitment to responsible development and continuous improvement within a business framework. The awards were presented in three categories, namely environment, health and safety, and socio-economic. Northrock Resources was presented with the award in the environment category for its voluntary waste gas reduction. The health and safety recognition went to Burlington Resources Canada Ltd. for superior office ergonomics, while the award in the socio-economic category was presented to Suncor Energy Inc. for Aboriginal business development. A brief overview of the achievements of each of these three companies was presented. tabs., figs.

  15. Eco-thermodynamics. Economics and the second law

    International Nuclear Information System (INIS)

    Ayres, Robert U.

    1998-01-01

    The laws of physics, especially the first and second laws of thermodynamics, have significant implications for economic theory. The major implications of the First Law (conservation of mass/energy) are straightforward and have been discussed at length elsewhere. In brief, raw material inputs to economic processes are not 'consumed'. Having been extracted from the environment in the first place, they eventually return to the environment as wastes. The economic implications of the Second Law (entropy law) are far more subtle. There is considerable literature, initiated by the work of Georgescu-Roegen, on the supposed constraints on economic growth imposed by the fact that economic processes utilize 'low-entropy' raw materials (fossil fuels and high grade metal ores) and discard 'high entropy' wastes. However, as a practical matter the flux of available low-entropy energy (exergy) from the sun is extremely large and certainly adequate to sustain economic activity in the solar system indefinitely, even though fossil fuel and metal ore stocks may eventually be exhausted. It is argued in this paper that the real economic significance of the Second Law lies in the fact that exergy is: (1) not conserved; and (2) is a useful common measure of resource quality, as well as quantity, applicable to both materials and energy. Thus, exergy can be used to measure and compare resource inputs and outputs, including wastes and losses. This is potentially important in itself. Moreover, since exergy is not conserved it is truly consumed (i.e. used up) in economic processes. Hence, exergy is no less a 'factor of production' than labor or capital. This fact has strong implications for economic growth theory, especially with regard to assessing the role of technical progress

  16. Fatal Metformin Overdose Presenting with Progressive Hyperglycemia

    Directory of Open Access Journals (Sweden)

    Suchard, Jeffrey R

    2008-08-01

    Full Text Available A 29-year-old man with no history of diabetes ingested over 60 grams of metformin in a suicide attempt. He presented to the emergency department with acute renal insufficiency, severe lactic acidosis, and rapidly-progressive hyperglycemia. The patient’s peak serum glucose level of 707 mg/dL is the highest yet reported in a case of metformin toxicity. Treatment included sodium bicarbonate infusion and hemodialysis, but the patient suffered several cardiac arrests with pulseless electrical activity and ultimately expired 25 hours after the ingestion.

  17. Tc-99m-bicisate (ECD)-brain-SPECT in rapidly progressive dementia; Hirn-SPECT mit Tc-99m-Bicisat (ECD) bei rasch progredientem dementiellen Syndrom

    Energy Technology Data Exchange (ETDEWEB)

    Marienhagen, J.; Eilles, C. [Regensburg Univ. (Germany). Abt. fuer Nuklearmedizin; Weingaertner, U.; Blaha, L. [Bezirkskrankenhaus Mainkofen (Germany). Psychiatrische Klinik; Zerr, I.; Poser, S. [Goettingen Univ. (Germany). Klinik und Poliklinik fuer Neurologie

    1999-07-01

    We present a 61-year-old male patient with progressive dementia. A brain SPECT with Tc-99m-bicisate was performed for confirmation of clinically suspected Alzheimer-dementia. At the time of the SPECT-investigation marked apraxia and aphasia besides severe dementia were present. Electrophysiological as well as anatomical neuroimaging findings showed non-diagnostic alterations. SPECT revealed distinct perfusion defects, which made Alzheimer Dementia unlikely. The further course of the patient was determined by rapidly progressive deterioration with development of akinetic mutism. Thereafter, increased levels of neuron-specific enolase as well as 14-3-3 proteins were found in the cerebro-spinal fluid (CSF). The patient finally died with signs of cerebral decortication. Due to the clinical course and the CSF-findings the patient's final diagnosis was Creutzfeld-Jakob-disease, nevertheless no autopsy was performed. The presented case report underscores the clinical utility of perfusion brain SPECT in the differential diagnosis of dementias. (orig.) [German] Wir berichten ueber einen 61jaehrigen Patienten mit progredientem dementiellen Syndrom, der unter der Verdachtsdiagnose einer Demenz vom Alzheimer-Typ (DAT) zur Hirn-SPECT-Untersuchung mit TC-99m-Bicisat (ECD) vorgestellt wurde. Zum Untersuchungszeitpunkt bestanden neben dem Vollbild einer Demenz eine ausgepraegte Apraxie und Aphasie bei unspezifischen Veraenderungen im EEG sowie der neuroradiologischen Bildgebung. In der Hirn-SPECT-Untersuchung fanden sich fuer eine DAT untypische ausgedehnte, vorwiegend rechtshemisphaerische Perfusionsstoerungen. Im weiteren Verlauf rasche Progredienz des Krankheitsbildes mit Entwicklung eines akinetischen Mutismus sowie Nachweis erhoehter Werte der neuronspezifischen Enolase und des 14-3-3-Proteins im Liquor. Der Patient verstarb schliesslich unter dem Bild einer Decortication. Aufgrund des klinischen Verlaufs sowie der Liquorbefunde wurde, da eine autoptische Befundsicherung

  18. Introduction to economic modeling for clinical rheumatologists: application to biologic agents in rheumatoid arthritis.

    Science.gov (United States)

    Marra, Carlo A; Bansback, Nick; Anis, Aslam H; Shojania, Kamran

    2011-03-01

    Rheumatoid arthritis (RA) is a chronic, debilitating inflammatory, progressive musculoskeletal disease that affects 0.5-1.0% of the adult population in Western countries. The joint destruction and progressive functional disability associated with uncontrolled RA result in tremendous impacts on health-related quality of life, ability to work, and mortality. In addition, the treatment of the disease and associated complications exact a substantial economic burden to the patients, their families, and society. In the last decade, several biological agents (biologics) have been approved for use in RA, revolutionizing treatment. These biologics, which target cytokines such as tumor necrosis factor or lymphocytes such as B or T cells, reduce functional disability and substantially slow the progression of joint damage. However, because these agents typically cost ten to 100 times more than existing available older drug therapies, there has been worldwide concern regarding their impact on healthcare budgets. As such, there has been increased attention towards economic evaluation as a means to determine whether, and in which subgroup of patients, these newer, more expensive agents confer appropriate value for their additional cost. Indeed, evaluations have guided coverage decisions for both private and public health insurance agencies such as the National Institute for Health and Clinical Excellence in the UK. The use of economic evaluations to determine value for money for these agents has attracted both debate and controversy. Some of the controversy is related to the appropriateness of the structure of, and assumptions underlying, the decision models employed to estimate the long-term costs and benefits of these agents over existing therapies. To fully appreciate the debate, one must first understand the basic principles of economic evaluation and the necessity for using decision models to evaluate cost effectiveness. To understand the basic principles of economic

  19. Information and Communications Technology Development and its Economic Context

    Directory of Open Access Journals (Sweden)

    Ales Pajgrt

    2013-01-01

    Full Text Available The contribution deals with economic context of Information a Communications Technology (ICT development’s analysis. Historical data of ICT revenue in USA for last 53 years were analyzed and were compared with the historical data in Czech Republic, Germany, China, India, Japan and Brazil for last 13 years. The ratio of ICT revenues to GDP was used as proper indicator in the examined countries to reflect the influences of the surrounding progress and define the individual progress stages. The formulation of the progress’ general rules and its prediction was done. It was monitored the dynamics of ICT sales, depending on its form and the influence of global economy.

  20. INVESTMENT FUNDS’ PERFORMANCE AND ECONOMIC GROWTH

    Directory of Open Access Journals (Sweden)

    Apolzan Carmen Maria

    2012-07-01

    Full Text Available In this paper we examine the performance of investment funds during the period 2006-2010, intending to comprise the portfolio performance’s dynamics before, during and after the present economic and financial crises climax. We categorize investment funds according to their investment strategy and geographical focus and distinguish a number of 11 classes. In order to analyze their returns’ dynamics, we create a fund performance index for each category using principal components method. The instability created in financial system in 2007 had a direct impact on institutional investors’ portfolios regardless of investment strategy, effects that have rapidly propagated on real economy. Analyzing index’s dynamics correlated with economic growth we conclude that financial and economic environment react in the same direction, but with a certain time delay, to instability factors. We also underline the major impact of boom and bust evolution of financial markets on real economy, cause of the current economic and financial crises.