Rao, Prof. Kaza Kesava

Indian Academy of Sciences (India)

Elected: 1992 Section: Engineering & Technology. Rao, Prof. ... Address: Professor, Department of Chemical Engineering, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact: ... Upcoming Refresher Courses. Topology 02 to 14 ...

The Hartshorne-Rao module of curves on rational normal scrolls

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Roberta Di Gennaro

2000-09-01

Full Text Available We study the Hartshorne-Rao module of curves lying on a rational normal scroll S_e of invariant e ≥ 0 in P^{e+3} .We calculate the Rao function, we characterize the aCM curves on S_e .Finally, we give an algorithm to check if a curve is aC M or not and, inthe second case, to calculate the Rao function.

Jagirdar, Prof. Balaji Rao

Indian Academy of Sciences (India)

Fellow Profile. Elected: 2013 Section: Chemistry. Jagirdar, Prof. Balaji Rao Ph.D. (Kansas State). Date of birth: 9 September 1965. Specialization: Organometallic Chemistry, Materials Chemistry, Catalysis Address: Department of Inorganic & Physical Chemistry, Indian Institute of Science, Bengaluru 560 012, Karnataka

Rao, Prof. Maddali Nageswara

Indian Academy of Sciences (India)

Rao, Prof. Maddali Nageswara Dr. rer. nat. (Cologne). Date of birth: 11 July 1931. Specialization: Solar System Physics, Mars Fundamental Research, Earth & Planetary Sciences and Lunar & Meteorite Sample Studies Address: 16931, Tower Ridge, Friendswood, Texas 77546, USA Contact: Residence: (+1-281) 993 9191

Rao, Prof. Valipe Ramgopal

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 2009 Section: Engineering & Technology. Rao, Prof. Valipe Ramgopal FNAE, FNASc, FNA, FIEEE. Date of birth: 16 August 1965. Specialization: Nanoelectronics and Nanotechnology Address: Director, Indian Institute of Technology, Hauz Khas, New Delhi 110 016, U.T.. Contact:

Valluri, Dr Sitaram Rao

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1971 Section: Engineering & Technology. Valluri, Dr Sitaram Rao Ph.D. (Caltech). Date of birth: 25 June 1924. Specialization: Metal Fatigue Address: 'Prashanthi', 659, 100 Feet Road, Indiranagar, Bengaluru 560 038, Karnataka Contact: Residence: (080) 2525 8294. YouTube ...

Nageswara Rao, Dr Gullapalli

Indian Academy of Sciences (India)

Nageswara Rao, Dr Gullapalli M.D. (Opthal.) (AIIMS), FAMS, FACS, FRCS, FNASc. Date of birth: 1 September 1945. Specialization: Cornea, Community Eye Health and Eye Care Policy & Planning Address: Distinguished Chair of Eye Health, LV Prasad Eye Institute, LV Prasad Marg, Banjara Hills, Hyderabad 500 034, A.P.

Rao, Prof. Kalya Jagannatha

Indian Academy of Sciences (India)

Rao, Prof. Kalya Jagannatha Ph.D. (IIT, Kanpur), D.Sc. (IISc), FNA, FNASc, D.Sc. (h.c., Univ. Bordeaux, France) Council Service: 1998-2003. Date of birth: 7 December 1940. Specialization: Physical Chemistry of Amorphous Solids & Ceramics and Phase Transitions Address: 187/1, Tadvanam Estate, Halasinganahalli Road ...

Miniaturization of Micro-Solder Bumps and Effect of IMC on Stress Distribution

Science.gov (United States)

Choudhury, Soud Farhan; Ladani, Leila

2016-07-01

As the joints become smaller in more advanced packages and devices, intermetallic (IMCs) volume ratio increases, which significantly impacts the overall mechanical behavior of joints. The existence of only a few grains of Sn (Tin) and IMC materials results in anisotropic elastic and plastic behavior which is not detectable using conventional finite element (FE) simulation with average properties for polycrystalline material. In this study, crystal plasticity finite element (CPFE) simulation is used to model the whole joint including copper, Sn solder and Cu6Sn5 IMC material. Experimental lap-shear test results for solder joints from the literature were used to validate the models. A comparative analysis between traditional FE, CPFE and experiments was conducted. The CPFE model was able to correlate the experiments more closely compared to traditional FE analysis because of its ability to capture micro-mechanical anisotropic behavior. Further analysis was conducted to evaluate the effect of IMC thickness on stress distribution in micro-bumps using a systematic numerical experiment with IMC thickness ranging from 0% to 80%. The analysis was conducted on micro-bumps with single crystal Sn and bicrystal Sn. The overall stress distribution and shear deformation changes as the IMC thickness increases. The model with higher IMC thickness shows a stiffer shear response, and provides a higher shear yield strength.

L V G Rao

Indian Academy of Sciences (India)

Home; Journals; Journal of Earth System Science. L V G Rao. Articles written in Journal of Earth System Science. Volume 109 Issue 2 June 2000 pp 255-265. Thermohaline structure and circulation in the upper layers of the southern Bay of Bengal during BOBMEX-Pilot (October — November 1998) · V Ramesh Babu V S N ...

Prof. Bookinkere Channakeshavaiah Subba Rao

Indian Academy of Sciences (India)

Annual Meetings · Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1975 Section: Chemistry. Subba Rao, Prof. Bookinkere Channakeshavaiah Ph.D. (Purdue). Date of birth: 8 December 1923

Integrated Marketing Communications (IMC) di PT Halo Rumah Bernyanyi

OpenAIRE

Rebekka Rismayanti

2017-01-01

Abstract: This research aims to describe the effectiveness of Integrated Marketing Communication (IMC) in PT Halo Rumah Bernyanyi which, from the perspective of marketing strategy, could be studied by analyzing the segmentation, targeting, and positioning. Using case-study method with in-depth interview, the result shows that the implementation of IMC at PT Halo Rumah Bernyayi is arranged in one single strategy and tend to neglect the complexities of running multi-brand family karaoke-house. ...

Integrated Marketing Communications (IMC) Di PT Halo Rumah Bernyanyi

OpenAIRE

Rismayanti, Rebekka

2016-01-01

: This research aims to describe the effectiveness of Integrated Marketing Communication (IMC) in PT Halo Rumah Bernyanyi which, from the perspective of marketing strategy, could be studied by analyzing the segmentation, targeting, and positioning. Using case-study method with in-depth interview, the result shows that the implementation of IMC at PT Halo Rumah Bernyayi is arranged in one single strategy and tend to neglect the complexities of running multi-brand family karaoke-house. This con...

The Transport Equation in Optically Thick Media: Discussion of IMC and its Diffusion Limit

Energy Technology Data Exchange (ETDEWEB)

Szoke, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Brooks, E. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2016-07-12

We discuss the limits of validity of the Implicit Monte Carlo (IMC) method for the transport of thermally emitted radiation. The weakened coupling between the radiation and material energy of the IMC method causes defects in handling problems with strong transients. We introduce an approach to asymptotic analysis for the transport equation that emphasizes the fact that the radiation and material temperatures are always different in time-dependent problems, and we use it to show that IMC does not produce the correct diffusion limit. As this is a defect of IMC in the continuous equations, no improvement to its discretization can remedy it.

Fast Erasure and Error decoding of Algebraic Geometry Codes up to the Feng-Rao Bound

DEFF Research Database (Denmark)

Jensen, Helge Elbrønd; Sakata, S.; Leonard, D.

1996-01-01

This paper gives an errata(that is erasure-and error-) decoding algorithm of one-point algebraic geometry codes up to the Feng-Rao designed minimum distance using Sakata's multidimensional generalization of the Berlekamp-massey algorithm and the votin procedure of Feng and Rao.......This paper gives an errata(that is erasure-and error-) decoding algorithm of one-point algebraic geometry codes up to the Feng-Rao designed minimum distance using Sakata's multidimensional generalization of the Berlekamp-massey algorithm and the votin procedure of Feng and Rao....

Computing the Feng-Rao distances for codes from order domains

DEFF Research Database (Denmark)

Ruano Benito, Diego

2007-01-01

We compute the Feng–Rao distance of a code coming from an order domain with a simplicial value semigroup. The main tool is the Apéry set of a semigroup that can be computed using a Gröbner basis.......We compute the Feng–Rao distance of a code coming from an order domain with a simplicial value semigroup. The main tool is the Apéry set of a semigroup that can be computed using a Gröbner basis....

The Cramér-Rao Bounds and Sensor Selection for Nonlinear Systems with Uncertain Observations.

Science.gov (United States)

Wang, Zhiguo; Shen, Xiaojing; Wang, Ping; Zhu, Yunmin

2018-04-05

This paper considers the problems of the posterior Cramér-Rao bound and sensor selection for multi-sensor nonlinear systems with uncertain observations. In order to effectively overcome the difficulties caused by uncertainty, we investigate two methods to derive the posterior Cramér-Rao bound. The first method is based on the recursive formula of the Cramér-Rao bound and the Gaussian mixture model. Nevertheless, it needs to compute a complex integral based on the joint probability density function of the sensor measurements and the target state. The computation burden of this method is relatively high, especially in large sensor networks. Inspired by the idea of the expectation maximization algorithm, the second method is to introduce some 0-1 latent variables to deal with the Gaussian mixture model. Since the regular condition of the posterior Cramér-Rao bound is unsatisfied for the discrete uncertain system, we use some continuous variables to approximate the discrete latent variables. Then, a new Cramér-Rao bound can be achieved by a limiting process of the Cramér-Rao bound of the continuous system. It avoids the complex integral, which can reduce the computation burden. Based on the new posterior Cramér-Rao bound, the optimal solution of the sensor selection problem can be derived analytically. Thus, it can be used to deal with the sensor selection of a large-scale sensor networks. Two typical numerical examples verify the effectiveness of the proposed methods.

PENERAPAN INTEGRATED MARKETING COMMUNICATION (IMC DI MEDIA RADIO SEGARA FM BANGKALAN

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Ipin Rahmadi

2016-03-01

Full Text Available This study intends to reveal the facts of the application of the concept of IMCwas done by radio Segara Bangkalan.Study used the concept theory of IMCwas applied of direct marketing, sales promotion, public relations, personalselling, advertising, and media interaction, marketing which relativelyapplied to the public audience of Segara radio.This of study used a qualitative descriptive method which intends to findout the phenomenon of concerns about the research subject. In holistic anddescriptive manner in the form of words and language, the data collectionmethods in this used study documentation, techniques, observation anddirectly interviews to the field.The application of IMC was good to increase the number of radio audience inSegara, from the six concepts of IMC, advertising, public relations, personalselling, sales promotion, direct marketing, and interactive ware marketing,applied directly by radio to the public, so that produce good results againstthe Segara radio.Keywords: IMC (Integrated Marketing Communication, Media Radio,Audience

PERAN IMC DALAM PEMILIHAN MOMMILK MANAHAN SOLO SEBAGAI PILIHAN KUNJUNGAN KONSUMEN

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Endang Sri Purwaningsih

2017-03-01

Full Text Available This study is to explore the IMC activity conducted by Mommilk Manahan Solo in attracting consumen interest. The research was conducted in Mommilk restaurant, Surakarta city. The quantitative descriptive methodology arranged to support the study while the measurement scale used Likert scale. The sample of this study was Mommilk costumers. The questioners were distributed to gauge the IMC activity, which can be devided into three specific factors; promotion and direct sell, public relation, and advertisement. In the outline of factors are the variables that influence the customers in selecting Mommilk as a preference. The result shows that the IMC activity is positively influence costumers to choose Mommilk as a preference. This study finds that several actions taken by the restaurant management successfully influenced the customers to choose Mommilk instead of others restaurants. Those actions become refence for the management to develop the service in order to attract the costumers.

Quantitative cine-left ventriculography - Superiority of 45 .deg. RAO view to straight AB view -

International Nuclear Information System (INIS)

Lim, Tae Hwan; Han, Man Chung

1981-01-01

The volumetry by cineangiocardiography is known to have the most diagnostic and prognostic value in the evaluation of various valvular heart diseases and ischemic heart diseases. Although many authors favor the area-length method for the volumetry of left ventricle, 45 .deg. RAO projection seems to be more simple, inexpensive and accurate technique, considering the positional relationship of cardiac valves and obliquity of the long axis of left ventricle within the chest cage. Authors present the anatomical, geometrical and radiological basis for the superiority of 45 .deg. RAO protection by analyzing 20 normal heart specimen and 115 cineangiocardiograms of valvular heart diseases, and the results as follows: 1. Blood flow and motility of the mitral and aortic valves can be more clearly demonstrated by 45 .deg. RAO projection than by AP view. 2. The long diameter of left ventricular silhouette made 45 .deg. RAO projection reflects 90% or more of real diameter. 3. In RAO 45 .deg. position, patient's left nipple is optimal and convenient level for the ruler offering accurate magnification coefficient of left ventricle. 4. Ejection fraction after the extrasystole is exaggerated regardless of the left ventricular function, so it is desirable to exclude the 2 or 3 beats after extrasystole

An Analysis of Source Tilting and Sub-cell Opacity Sampling for IMC

Energy Technology Data Exchange (ETDEWEB)

Wollaeger, Ryan T. [Los Alamos National Laboratory; Urbatsch, Todd J. [Los Alamos National Laboratory; Wollaber, Allan B. [Los Alamos National Laboratory; Densmore, Jeffery D. [Los Alamos National Laboratory

2012-08-02

Implicit Monte Carlo (IMC) is a stochastic method for solving the radiative transfer equations for multiphysics application with the material in local thermodynamic equilibrium. The IMC method employs a fictitious scattering term that is computed from an implicit discretization of the material temperature equation. Unfortunately, the original histogram representation of the temperature and opacity with respect to the spatial domain leads to nonphysically fast propagation of radiation waves through optically thick material. In the past, heuristic source tilting schemes have been used to mitigate the numerical teleportation error of the radiation particles in IMC that cause this overly rapid radiation wave propagation. While improving the material temperature profile throughout the time duration, these tilting schemes alone do not generally alleviate the teleportation error to suitable levels. Another means of potentially reducing teleportation error in IMC is implementing continuous sub-cell opacities based on sub-cell temperature profiles. We present here an analysis of source tilting and continuous sub-cell opacity sampling applied to various discretizations of the temperature equation. Through this analysis, we demonstrate that applying both heuristics does not necessarily yield more accurate results if the discretization of the material equation is inconsistent with the Monte Carlo sub-cell transport.

Fast Erasure-and error decoding of algebraic geometry codes up to the Feng-Rao bound

DEFF Research Database (Denmark)

Høholdt, Tom; Jensen, Helge Elbrønd; Sakata, Shojiro

1998-01-01

This correspondence gives an errata (that is erasure-and error-) decoding algorithm of one-point algebraic-geometry codes up to the Feng-Rao designed minimum distance using Sakata's multidimensional generalization of the Berlekamp-Massey algorithm and the voting procedure of Feng and Rao....

Characteristics of indomethacin-saccharin (IMC-SAC) co-crystals prepared by an anti-solvent crystallization process.

Science.gov (United States)

Chun, Nan-Hee; Wang, In-Chun; Lee, Min-Jeong; Jung, Yun-Taek; Lee, Sangkil; Kim, Woo-Sik; Choi, Guang J

2013-11-01

The creation of co-crystals of various insoluble drug substances has been extensively investigated as a promising approach to improve their pharmaceutical performance. In this study, co-crystal powders of indomethacin and saccharin (IMC-SAC) were prepared by an anti-solvent (water) addition and compared with co-crystals by evaporation method. No successful synthesis of a pharmaceutical co-crystal powder via an anti-solvent approach has been reported. Among solvents examined, methanol was practically the only one that resulted in the formation of highly pure IMC-SAC co-crystal powders by anti-solvent approach. The mechanism of a preferential formation of IMC-SAC co-crystal to IMC was explained with two aspects: phase solubility diagram and solution complexation concept. Accordingly, the anti-solvent approach can be considered as a competitive route for producing pharmaceutical co-crystal powders with acceptable properties. Copyright © 2013 Elsevier B.V. All rights reserved.

Medical and radiological aspects of emergency preparedness and response at SevRAO facilities.

Science.gov (United States)

Savkin, M N; Sneve, M K; Grachev, M I; Frolov, G P; Shinkarev, S M; Jaworska, A

2008-12-01

Regulatory cooperation between the Norwegian Radiation Protection Authority and the Federal Medical Biological Agency (FMBA) of the Russian Federation has the overall goal of promoting improvements in radiation protection in Northwest Russia. One of the projects in this programme has the objectives to review and improve the existing medical emergency preparedness capabilities at the sites for temporary storage of spent nuclear fuel and radioactive waste. These are operated by SevRAO at Andreeva Bay and in Gremikha village on the Kola Peninsula. The work is also intended to provide a better basis for regulation of emergency response and medical emergency preparedness at similar facilities elsewhere in Russia. The purpose of this paper is to present the main results of that project, implemented by the Burnasyan Federal Medical Biophysical Centre. The first task was an analysis of the regulatory requirements and the current state of preparedness for medical emergency response at the SevRAO facilities. Although Russian regulatory documents are mostly consistent with international recommendations, some distinctions lead to numerical differences in operational intervention criteria under otherwise similar conditions. Radiological threats relating to possible accidents, and related gaps in the regulation of SevRAO facilities, were also identified. As part of the project, a special exercise on emergency medical response on-site at Andreeva Bay was prepared and carried out, and recommendations were proposed after the exercise. Following fruitful dialogue among regulators, designers and operators, special regulatory guidance has been issued by FMBA to account for the specific and unusual features of the SevRAO facilities. Detailed sections relate to the prevention of accidents, and emergency preparedness and response, supplementing the basic Russian regulatory requirements. Overall it is concluded that (a) the provision of medical and sanitary components of emergency

A feedforward IMC structure for controlling the charging temperature of a TES system of a solar cooker

International Nuclear Information System (INIS)

Mawire, A.; McPherson, M.

2008-01-01

A feedforward internal model control (IMC) structure for controlling and maintaining the outlet charging temperature of a thermal energy storage (TES) system of a solar cooker is presented. The TES system consists of a packed pebble bed in thermal contact with a heat transfer oil contained in a storage tank. An electrical hot plate simulates the collector/concentrator which heats up the oil circulating in a hollow copper spiral coil thus charging the storage. A model for the collector/concentrator system is developed to enable simulation of the feedforward IMC structure. Using a Simulink block model, the simulation results reveal that a feedforward IMC structure performs better than a feedforward structure. The feedforward IMC structure is tested experimentally and the performance of the control structure is acceptable within a few degrees of the set temperatures. Experimental results are also compared with the simulation results. The simulated responses are found to relate closely to the experimental ones and any discrepancies between the two are discussed. Furthermore, the feedforward IMC structure is also compared experimentally with a combined feedforward and PID feedback structure. Results of the comparison indicate that the feedforward IMC structure performs better than the combined feedforward and PID feedback structure. The thermal profile of the storage during the charging experiment with the feedforward IMC structure is also presented and the results obtained from the storage profile indicate that the storage tank is thermally stratified

Limitaciones del IMC como indicador exclusivo de estado nutricional

Directory of Open Access Journals (Sweden)

Moreno Romero, Susana

2007-01-01

Full Text Available El presente trabajo tiene como objetivo determinar el potencial diagnóstico y las limitaciones del uso del Índice de Masa Corporal como único indicador del estado nutricional. Para ello se analizó una muestra constituida por 2155 sujetos de ambos sexos, con edades comprendidas entre los 6 y 18 años y pertenecientes a tres poblaciones jujeñas que difieren en ubicación altitudinal y nivel socieconómico (NSE: 1. Susques, localidad rural situada a 3675 m.s.n.m; 2. Alto Comedero, barrio periférico de San Salvador de Jujuy (1250 m.s.n.m. de NSE bajo; y 3. José Hernández, muestra representativa del estrato SE elevado de la misma capital. Se tomaron las medidas directas de talla, peso, perímetro braquial y pliegues de grasa subcutánea tricipital y subescapular, entre otras. A partir de éstas, se calculó el IMC y las áreas tisulares del brazo. Se establecieron las categorías nutricionales en función de los percentilos establecidos por el NHANES I y II para la talla, IMC, área magra y grasa del brazo y pliegues tricipital y subescapular. Al comparar los resultados obtenidos para cada variable se comprueba como el uso exclusivo del IMC enmascara importantes patologías nutricionales, tanto por defecto como por exceso.

Stochastic processes and functional analysis a volume of recent advances in honor of M. M. Rao

CERN Document Server

Krinik, Alan C

2004-01-01

This extraordinary compilation is an expansion of the recent American Mathematical Society Special Session celebrating M. M. Rao's distinguished career and includes most of the presented papers as well as ancillary contributions from session invitees. This book shows the effectiveness of abstract analysis for solving fundamental problems of stochastic theory, specifically the use of functional analytic methods for elucidating stochastic processes, as made manifest in M. M. Rao's prolific research achievements. Featuring a biography of M. M. Rao, a complete bibliography of his published works,

Aktivitas Komunikasi Pemasaran Terpadu (IMC Pemerintah Kota Ambon dalam Mengkomunikasikan Brand “Ambon City Of Music” Melalui Kegiatan Tiga Pilar IMC

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Arthur Solsolay

2016-07-01

Full Text Available Ambon city is one of the tourist destinations in the province of Maluku, kept the charm and appeal of natural, historical, religious, culinary, education, art, culture and customs. To develop and trigger the development of musical art in the city of Ambon, Ambon city government felt the need to form a brand that became a brand differentiator and became icons of tourism in Ambon. Brand "Ambon City of Music" was initiated in hopes of becoming a starting point for the development of city Ambon become more competitive through an integrated marketing communications activities in brand communication. Research to describe and analyze the concept of the three pillars of IMC in the steps taken by the Government of Ambon in communicating the brand "Ambon City of Music". other research method used is descriptive qualitative case study approach. R esearchers found that the government has made strategic moves in IMC pillar concept is to approach audiences (government, private sector / stakeholder, elements of the community and the media (elements of the marketing communication mix.

International dimensions of the IMC

Directory of Open Access Journals (Sweden)

Bešlin Marija

2005-01-01

Full Text Available Seems that one of the basic challenge facing marketing organizations today related to shift from traditional functions and operations to the new pattern of the 21st century and the global marketplace. The old traditional models are less and less relevant growing tendency of world market's complexity and increasing competitive efforts ask for "fresh approach" and types of communication with the consumers and other stakeholders. Accordingly, the traditional (linear model have to be replaced with IMC integrated and interactive marketing communication. Shift toward integrated marketing communications is one of the most significant marketing communication development occurred during the 1990s and such direction is continuing in the new century or time to come.

Response of Peripheral Blood Lymphocytes from RAO-affected Horses to b2-Agonist Stimulation

OpenAIRE

Werner Becker, Marianne Patricia

2011-01-01

Recurrent airway obstruction (RAO) affects middle-age horses, inducing bronchoconstriction and airway inflammation. β2-agonists like salbutamol are used as treatment, promoting airway smooth muscle (ASM) relaxation and bronchodilation. In addition to ASM, inflammatory cells express the β2-adrenoreceptors (β2-AR). In other species, β2-agonists promote peripheral blood lymphocyte (PBL) cytokine expression towards a pro-inflammatory phenotype. RAO horses are a good model for evaluating chron...

Learning Through Media; An IMC Handbook for Chelmsford Teachers.

Science.gov (United States)

Morrow, James; Wallace, Daniel

This handbook is designed to provide basic information that is necessary to use the Chelmsford School System's Instructional Media Center (IMC). It defines six different media (print, sound, television, photography, movies and design) and suggests a series of separate classroom production activities in each. An emphasis is given to the ways in…

Analysing Institutions Interdisciplinarity by Extensive Use of Rao-Stirling Diversity Index.

Science.gov (United States)

Cassi, Lorenzo; Champeimont, Raphaël; Mescheba, Wilfriedo; de Turckheim, Élisabeth

2017-01-01

This paper shows how the Rao-Stirling diversity index may be extensively used for positioning and comparing institutions interdisciplinary practices. Two decompositions of this index make it possible to explore different components of the diversity of the cited references in a corpus of publications. The paper aims at demonstrating how these bibliometric tools can be used for comparing institutions in a research field by highlighting collaboration orientations and institutions strategies. To make the method available and easy to use for indicator users, this paper first recalls a previous result on the decomposition of the Rao-Stirling index into multidisciplinarity and interdisciplinarity components, then proposes a new decomposition to further explore the profile of research collaborations and finally presents an application to Neuroscience research in French universities.

Cross-cultural adaptation and validation of the French version of the Rheumatoid and Arthritis Outcome Score (RAOS)

DEFF Research Database (Denmark)

Duval, Aurelie; Maillefert, Jean Francis; Gossec, Laure

2010-01-01

The Rheumatoid and Arthritis Outcome Score (RAOS) was recently developed to evaluate functional disability and quality of life in rheumatoid arthritis (RA) patients suffering from lower limb symptoms. The aims of this study were to cross-culturally adapt the RAOS into French and to assess its...

Tsuwalhkalh Ti Tmicwa (The Land is Ours): Stat'imc Self-Determination in the Face of Large-Scale Hydro-electric Development

Science.gov (United States)

Moritz, Sarah Carmen

In Canada, First Nations asserting authority over their lands are developing diverse strategies to overcome the state''s dogmatic insistence on jurisdictional sovereignty. This movement corresponds to the wider context of the challenges faced by indigenous people to use their own ways of knowing to resist or reformulate legal doctrines and political tenets based on colonial power. Interior Salish Stat'imc people identify themselves through a strong and ongoing social relationship with Sataqwa7, the Fraser River, and the "Valley of Plenty"---now known as the flooded Bridge River Valley---maintained through Stat'imc knowledge and cultural practice and demonstrated by talk of '"the Stat'imc right to fish" and Tsuwalhkalh Ti Tmicwa (The Land is Ours). Stat'imc fishers are prepared to contest and resist any regulatory system that is understood to impact this right to fish while they advocate their own ways of sustainable fishing and water management. Based on ethnographic research in collaboration with Stat'imc people, this thesis explores some of these often successful contestations especially in the context of increasing territorial governance and by example of the rapidly transforming relationship between Stat'imc, BC Hydro and the Province of BC. Interior Salish Stat'imc people are currently navigating through a significant phase of increasing jurisdiction and authority and recognition of (unsettled) territorial property relationships. This very dynamic process is marked by strategic collaborations, compensation for 'infringements' on St'a'imc Title and Rights, and conservation efforts to protect their home. An important example is the changing relationship between Stat'imc people and BC Hydro---a relationship between two groups with radically different cultures and agendas: Stat'imc people in a struggle for self-determination, social justice and cultural survival and BC Hydro, a corporate culture, with the agenda to provide hydro-electric power to BC, maintain

On an inner product over Imc *-algebras

International Nuclear Information System (INIS)

Mohammad, N.; Verjovsky, A.

1991-08-01

An inner product is defined on a commutative *-semisimple separable Frechet Q Imc *-algebra A and the resultant space A m is shown to be a topological *-algebra. It is also proved that every maximal ideal M of A is A m -closed and thus A can be decomposed into A = M + M perpendicular . Further, it is shown that a norm can be defined on A which makes it into a pre C * -algebra. A completeness criterion for A m is established. (author). 10 refs

Quantum metrology in open systems: dissipative Cramér-Rao bound.

Science.gov (United States)

Alipour, S; Mehboudi, M; Rezakhani, A T

2014-03-28

Estimation of parameters is a pivotal task throughout science and technology. The quantum Cramér-Rao bound provides a fundamental limit of precision allowed to be achieved under quantum theory. For closed quantum systems, it has been shown how the estimation precision depends on the underlying dynamics. Here, we propose a general formulation for metrology scenarios in open quantum systems, aiming to relate the precision more directly to properties of the underlying dynamics. This feature may be employed to enhance an estimation precision, e.g., by quantum control techniques. Specifically, we derive a Cramér-Rao bound for a fairly large class of open system dynamics, which is governed by a (time-dependent) dynamical semigroup map. We illustrate the utility of this scenario through three examples.

In vitro evaluation of antimicrobial activity of Lactobacillus rhamnosus IMC 501(®) , Lactobacillus paracasei IMC 502(®) and SYNBIO(®) against pathogens.

Science.gov (United States)

Coman, M M; Verdenelli, M C; Cecchini, C; Silvi, S; Orpianesi, C; Boyko, N; Cresci, A

2014-08-01

Probiotic lactobacilli have a great potential to produce antimicrobial compounds that inhibit and control the microbial pathogen growth. The antimicrobial and antifungal activities of two probiotic strains, Lactobacillus rhamnosus IMC 501(®) and Lactobacillus paracasei IMC 502(®) , and their 1 : 1 combination, named SYNBIO(®) , were studied using four different methods. Using two modified streak methods and a well diffusion method, the inhibitory activity of the probiotics and their metabolites towards six Gram-positive, nine Gram-negative pathogenic bacterial strains and eight Candida strains was tested. Antagonistic effect of probiotic Lactobacillus strains was also investigated by coculturing assay highlighting a significant inhibition of most of the pathogens tested in this study. The combination SYNBIO(®) showed a microbicidal activity against most of the strains tested in the study. Compared with the control, most of the pathogenic bacteria and yeast were inhibited by all probiotic strains tested to various degrees. Screening Lactobacillus strains according to their activity in various environmental conditions could precede the clinical efficacy studies for adjunct treatment with probiotics in cure of different gastrointestinal and vaginal tract infections. © 2014 The Society for Applied Microbiology.

The Impact of IMC on Advertising and Public Relations Education.

Science.gov (United States)

Griffin, W. Glenn; Pasadeos, Yorgo

1998-01-01

Surveys advertising and public relations faculty members with regard to IMC (Integrated Marketing Communications) and its impact on current curricula. Finds (1) areas of discontent with current course curricula; (2) evidence of "separate agendas" between advertising and public relations educators on this issue; and (3) evidence of a generation gap…

Interfacial Reaction and IMC Growth of an Ultrasonically Soldered Cu/SAC305/Cu Structure during Isothermal Aging

Directory of Open Access Journals (Sweden)

Yulong Li

2018-01-01

Full Text Available In order to accelerate the growth of interfacial intermetallic compound (IMC layers in a soldering structure, Cu/SAC305/Cu was first ultrasonically spot soldered and then subjected to isothermal aging. Relatively short vibration times, i.e., 400 ms and 800 ms, were used for the ultrasonic soldering. The isothermal aging was conducted at 150 °C for 0, 120, 240, and 360 h. The evolution of microstructure, the IMC layer growth mechanism during aging, and the shear strength of the joints after aging were systemically investigated. Results showed the following. (i Formation of intermetallic compounds was accelerated by ultrasonic cavitation and streaming effects, the thickness of the interfacial Cu6Sn5 layer increased with aging time, and a thin Cu3Sn layer was identified after aging for 360 h. (ii The growth of the interfacial IMC layer of the ultrasonically soldered Cu/SAC305/Cu joints followed a linear function of the square root of the aging time, revealing a diffusion-controlled mechanism. (iii The tensile shear strength of the joint decreased to a small extent with increasing aging time, owing to the combined effects of IMC grain coarsening and the increase of the interfacial IMC. (iv Finally, although the fracture surfaces and failure locations of the joint soldered with 400 ms and 800 ms vibration times show similar characteristics, they are influenced by the aging time.

Effect of Ni addition to the Cu substrate on the interfacial reaction and IMC growth with Sn3.0Ag0.5Cu solder

Science.gov (United States)

Zhang, Xudong; Hu, Xiaowu; Jiang, Xiongxin; Li, Yulong

2018-04-01

The formation and growth of intermetallic compound (IMC) layer at the interface between Sn3.0Ag0.5Cu (SAC305) solder and Cu- xNi ( x = 0, 0.5, 1.5, 5, 10 wt%) substrate during reflowing and aging were investigated. The soldering was conducted at 270 °C using reflowing method, following by aging treatment at 150 °C for up to 360 h. The experimental results indicated that the total thickness of IMC increased with increasing aging time. The scallop-like Cu6Sn5 and planar-like Cu3Sn IMC layer were observed between SAC305 solder and purely Cu substrate. As the content of Ni element in Cu substrate was 0.5% or 1.5%, the scallop-like Cu6Sn5 and planar-like Cu3Sn IMC layer were still found between solder and Cu-Ni substrate and the total thickness of IMC layer decreased with the increasing Ni content. Besides, when the Ni content was up to 5%, the long prismatic (Cu,Ni)6Sn5 phase was the only product between solder and substrate and the total thickness of IMC layer increased significantly. Interestingly, the total thickness of IMC decreased slightly as the Ni addition was up to 10%. In the end, the grains of interfacial IMC layer became coarser with aging time increasing while the addition of Ni in Cu substrate could refine IMC grains.

Neutrophil and macrophage apoptosis in bronchoalveolar lavage fluid from healthy horses and horses with recurrent airway obstruction (RAO)

Science.gov (United States)

2014-01-01

Background Dysregulation of apoptosis has been implicated in a range of diseases including tumors, neurodegenerative and autoimmine diseases, as well as allergic asthma and chronic obstructive pulmonary disease (COPD) in humans. Although it has a different pathophysiology, delayed apoptosis of various inflammatory cells may play a pivotal role in the development of recurrent airway obstruction (RAO) in horses. Reduction of inflammatory cell apoptosis or a dysregulation of this process could lead to chronic inflammation and tissue injury. Therefore, the aim of this study was to investigate the rate of apoptosis and necrosis of neutrophils and macrophages in bronchoalveolar lavage fluid obtained from seven horses suffering from RAO (study group) and seven control horses. Results We demonstrated that neutrophil/macrophage apoptosis is altered in RAO-affected horses compared with the control group in the BAL fluid. We found a significant difference between the median percentage of early and late apoptosis of neutrophils between the study and control group of horses. Moreover, we found a positive correlation between the rate of apoptosis and the median percentage of macrophages in RAO-affected horses. Conclusion The findings suggest that apoptosis dysregulation may play a significant role in the pathogenesis of RAO. However, further studies are needed to clarify the role of altered apoptosis in the course of equine recurrent airway obstruction. PMID:24460911

Coordinating IMC-PID and adaptive SMC controllers for a PEMFC.

Science.gov (United States)

Wang, Guo-Liang; Wang, Yong; Shi, Jun-Hai; Shao, Hui-He

2010-01-01

For a Proton Exchange Membrane Fuel Cell (PEMFC) power plant with a methanol reformer, the process parameters and power output are considered simultaneously to avoid violation of the constraints and to keep the fuel cell power plant safe and effective. In this paper, a novel coordinating scheme is proposed by combining an Internal Model Control (IMC) based PID Control and adaptive Sliding Mode Control (SMC). The IMC-PID controller is designed for the reformer of the fuel flow rate according to the expected first-order dynamic properties. The adaptive SMC controller of the fuel cell current has been designed using the constant plus proportional rate reaching law. The parameters of the SMC controller are adaptively tuned according to the response of the fuel flow rate control system. When the power output controller feeds back the current references to these two controllers, the coordinating controllers system works in a system-wide way. The simulation results of the PEMFC power plant demonstrate the effectiveness of the proposed method. 2009 ISA. Published by Elsevier Ltd. All rights reserved.

An Example of an Improvable Rao-Blackwell Improvement, Inefficient Maximum Likelihood Estimator, and Unbiased Generalized Bayes Estimator.

Science.gov (United States)

Galili, Tal; Meilijson, Isaac

2016-01-02

The Rao-Blackwell theorem offers a procedure for converting a crude unbiased estimator of a parameter θ into a "better" one, in fact unique and optimal if the improvement is based on a minimal sufficient statistic that is complete. In contrast, behind every minimal sufficient statistic that is not complete, there is an improvable Rao-Blackwell improvement. This is illustrated via a simple example based on the uniform distribution, in which a rather natural Rao-Blackwell improvement is uniformly improvable. Furthermore, in this example the maximum likelihood estimator is inefficient, and an unbiased generalized Bayes estimator performs exceptionally well. Counterexamples of this sort can be useful didactic tools for explaining the true nature of a methodology and possible consequences when some of the assumptions are violated. [Received December 2014. Revised September 2015.].

Rao Quan Feasibility Study - Phase 1: Toxic Substances and Contamination (Final Report)

Energy Technology Data Exchange (ETDEWEB)

Berge, Dag; Knutzen, Jon

1997-12-31

Due to wartime activity in the Khe Sanh area, it was expected that damming of the river Rao Quan could wash out diffuse pollutants from the ground and from possible military dump sites. As discussed in this report, the rivers Rao Quan, Khe Nghi and Quang Tri contain relatively soft water. The buffer capacity against acidification is good. The sulphate concentration is low. The water will not be aggressive against concrete. The maximum particulate content in the wet season is low. The nutrient content of the rivers is relatively low. The phosphorus content correlated well with the turbidity, which indicates that the phosphorus is bound to particles. Khe Nghi has significantly higher nitrogen content than the other rivers, which may indicate some slight impact from animal husbandry. However, there was no eutrophication. The content of heavy metals is low and indicates no pollution from the military activities in the area. The water is well suited for irrigation. There was no indication from the analysed fish , the river sediments from Rao Quan or the top soil of the rice fields of any significant dioxin contamination. The content was similar to normal back ground levels caused by diffuse atmospheric fallout. The herbicide Agent Orange in 1962-1975 was applied mostly in the southernmost part of the country and contamination from it in the Quang Tri Province is not expected. 13 refs., 4 figs., 4 tabs.

Effect of buckwheat flour and oat bran on growth and cell viability of the probiotic strains Lactobacillus rhamnosus IMC 501®, Lactobacillus paracasei IMC 502® and their combination SYNBIO®, in synbiotic fermented milk.

Science.gov (United States)

Coman, Maria Magdalena; Verdenelli, Maria Cristina; Cecchini, Cinzia; Silvi, Stefania; Vasile, Aida; Bahrim, Gabriela Elena; Orpianesi, Carla; Cresci, Alberto

2013-10-15

Fermented foods have a great significance since they provide and preserve large quantities of nutritious foods in a wide diversity of flavors, aromas and texture, which enrich the human diet. Originally fermented milks were developed as a means of preserving nutrients and are the most representatives of the category. The first aim of this study was to screen the effect of buckwheat flour and oat bran as prebiotics on the production of probiotic fiber-enriched fermented milks, by investigating the kinetics of acidification of buckwheat flour- and oat bran-supplemented milk fermented by Lactobacillus rhamnosus IMC 501®, Lactobacillus paracasei IMC 502® and their 1:1 combination named SYNBIO®. The probiotic strains viability, pH and sensory characteristics of the fermented fiber-enriched milk products, stored at 4 °C for 28 days were also monitored. The results showed that supplementation of whole milk with the tested probiotic strains and the two vegetable substrates results in a significant faster lowering of the pH. Also, the stability of L. rhamnosus IMC 501®, L. paracasei IMC 502® and SYNBIO® during storage at 4 °C for 28 days in buckwheat flour- and oat bran-supplemented samples was remarkably enhanced. The second aim of the study was to develop a new synbiotic product using the best combination of probiotics and prebiotics by promoting better growth and survival and be acceptable to the consumers with high concentration of probiotic strain. This new product was used to conduct a human feeding trial to validate the fermented milk as a carrier for transporting bacterial cells into the human gastrointestinal tract. The probiotic strains were recovered from fecal samples in 40 out of 40 volunteers fed for 4 weeks one portion per day of synbiotic fermented milk carrying about 10(9) viable cells. © 2013.

IMC DOS ALUNOS DO 4º PERÍODO DO CURSO TÉCNICO EM ALIMENTOS DO INSTITUTO FEDERAL DE GOIÁS CAMPI/INHUMAS.

Directory of Open Access Journals (Sweden)

Jefferson Jorcelino Máximo

2011-03-01

Full Text Available Introdução: O índice de massa corpórea – IMC é uma medida simples do grau de obesidade de um indivíduo, sendo utilizada para mensurar o nível de adiposidade em estudos populacionais. Com isso, tem se verificado que a obesidade está se tornando um dos maiores problemas de saúde pública, pois está intimamente associada a incidência de doenças cardiovasculares. Objetivo: Analisar o índice de massa corpórea dos alunos do 4º período do curso técnico em alimentos. Método: Dezenove (19 alunos com idade entre 18 e 46 anos foram submetidos a avaliação biométrica (massa corporal e estatura. Para o cálculo do IMC foi utilizado o índice de Quetelet (Peso/Altura² peso em quilogramas dividido pela altura em metros ao quadrado, sendo que desses, 17 do sexo feminino e 02 do sexo masculino. Resultado: Os resultados obtidos pela amostra foram classificados nas categorias de IMC < 20 Abaixo do peso; IMC 20 a 25 Kg/m² Peso Normal; IMC 25,1 a 29,9 Kg/m² Sobrepeso; IMC 30,0 a 39,9 Kg/m² Obeso e < 40 Kg/m² Obeso Mórbido. Classificação segundo a Organização Mundial de Saúde OMS.

Integrated Marketing Communication (Imc) Green Radio 96,7 Fm Pekanbaru Dalam Membangun Brand Image Sebagai Media Berbasis Lingkungan

OpenAIRE

Marbun, Tresia Br; ", Rumyeni

2017-01-01

Integrated Marketing Communication (IMC) is the company's effort to integrate and coordinate all communication channels to deliver its message clearly, consistently and strongly influences its organization and products. Green Radio 96.7 FM Pekanbaru is the only electronic media that focuses on broadcasting news Environmental issues in Riau Province. This radio builds brand image as an environment-based media by choosing to use Integrated Marketing Communication (IMC). This study aims to find ...

Understanding the development and diffusion of integrated marketing communications (IMC) : A metaphorical perspective

NARCIS (Netherlands)

Cornelissen, J.P.; Thøger, L.; Vijn, P.

2006-01-01

In recent years, theoretical commentaries and empirical research on the concept of Integrated Marketing Communications (IMC) have been concerned with its development and specification as a theoretical construct, and its diffusion among academics and practitioner populations across the globe. In this

LEADER WITH GOLDEN HEART - SRI CA. A. RAGHAVENDRA RAO

OpenAIRE

Aithal Sreeramana P.; Suresh Kumar P.M.; Shailashri V.T.; Prithi Jeevan

2015-01-01

Srinivas group of colleges has come into being from a humble beginning in1988, into a chain of institutions due to its visionary founder Sri CA A Raghavendra Rao. Today it spreads over 18 colleges with 70 courses and over 12000 students generating livelihood to 3500 employees and their families. His leadership qualities and values are distinct. He is wired like business people but bottom line oriented and extraordinarily committed to results. The steep ascend from humble person to an accompl...

ASSOCIAÇÃO ENTRE O ÍNDICE DE ADIPOSIDADE CORPORAL (IAC E ÍNDICE DE MASSA CORPORAL (IMC EM MULHERES PRATICANTES DE TREINAMENTO RESISTIDO

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William Cordeiro de Souza

2014-04-01

Full Text Available O presente estudo buscou como objetivo realizar uma relação entre o índice de adiposidade corporal (IAC e índice de massa corporal (IMC em mulheres praticantes de treinamento resistido. A mostra foi composta por 14 mulheres (idade: 27 ± 3.96 anos praticantes de treinamento resistido (3 a 5 dias por semana. Foram avaliados o peso e a estatura para obtenção de IMC e circunferência do quadril (CQ na determinação do índice de adiposidade corporal. Na análise dos dados foi utilizada à estatística descritiva: Média, desvio padrão (dp, frequência percentual (% e o fator de correlação de Pearson (r com nível de significância de 0,05. Nos resultados obtidos observou-se que no IMC todas as avaliadas estão dentro dos padrões estabelecidos (eutroficas. Com relação ao IAC, 28.57% (n=4 das mulheres avaliadas estão dentro do padrão “Ideal”, 42.87% (n=6 com seu percentual “Moderado” e 28.57% (n= 4 com “Excesso de gordura”. Quanto à circunferência do quadril foi verificado que as todas as avaliadas (n=14 estão com dentro dos padrões recomendo. Não foram encontradas correlações entre IMC e IAC (r =0,392 e p =0,164, nem entre IMC e CQ (r =0,272 e p =0,345. Ao finalizar o estudo foi verificado que não houve diferenças significativas entre IMC e IAC; nem para o IMC com a CQ.

Nutrient modeling for a semi-intensive IMC pond: an MS-Excel approach.

Science.gov (United States)

Ray, Lala I P; Mal, B C; Moulick, S

2017-11-01

Semi-intensive Indian Major Carp (IMC) culture was practised in polythene lined dugout ponds at the Aquacultural Farm of Indian Institute of Technology, Kharagpur, West Bengal for 3 consecutive years at three different stocking densities (S.D), viz., 20,000, 35,000 and 50,000 numbers of fingerlings per hectare of water spread area. Fingerlings of Catla, Rohu and Mrigal were raised at a stocking ratio of 4:3:3. Total ammonia nitrogen (TAN) value along with other fishpond water quality parameters was monitored at 1 day intervals to ensure a good water ecosystem for a better fish growth. Water exchange was carried out before the TAN reached the critical limit. Field data on TAN obtained from the cultured fishponds stocked with three different stocking densities were used to study the dynamics of TAN. A developed model used to study the nutrient dynamics in shrimp pond was used to validate the observed data in the IMC pond ecosystem. Two years of observed TAN data were used to calibrate the spreadsheet model and the same model was validated using the third year observed data. The manual calibration based on the trial and error process of parameters adjustments was used and several simulations were performed by changing the model parameters. After adjustment of each parameter, the simulated and measured values of the water quality parameters were compared to judge the improvement in the model prediction. Forward finite difference discretization method was used in a MS-Excel spreadsheet to calibrate and validate the model for obtaining the TAN levels during the culture period. Observed data from the cultured fishponds of three different S.D were used to standardize 13 model parameters. The efficiency of the developed spreadsheet model was found to be more than 90% for the TAN estimation in the IMC cultured fishponds.

The Rao-Blackwellized Particle Filter: A Filter Bank Implementation

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Karlsson Rickard

2010-01-01

Full Text Available For computational efficiency, it is important to utilize model structure in particle filtering. One of the most important cases occurs when there exists a linear Gaussian substructure, which can be efficiently handled by Kalman filters. This is the standard formulation of the Rao-Blackwellized particle filter (RBPF. This contribution suggests an alternative formulation of this well-known result that facilitates reuse of standard filtering components and which is also suitable for object-oriented programming. Our RBPF formulation can be seen as a Kalman filter bank with stochastic branching and pruning.

Detection of image structures using the Fisher information and the Rao metric.

Science.gov (United States)

Maybank, Stephen J

2004-12-01

In many detection problems, the structures to be detected are parameterized by the points of a parameter space. If the conditional probability density function for the measurements is known, then detection can be achieved by sampling the parameter space at a finite number of points and checking each point to see if the corresponding structure is supported by the data. The number of samples and the distances between neighboring samples are calculated using the Rao metric on the parameter space. The Rao metric is obtained from the Fisher information which is, in turn, obtained from the conditional probability density function. An upper bound is obtained for the probability of a false detection. The calculations are simplified in the low noise case by making an asymptotic approximation to the Fisher information. An application to line detection is described. Expressions are obtained for the asymptotic approximation to the Fisher information, the volume of the parameter space, and the number of samples. The time complexity for line detection is estimated. An experimental comparison is made with a Hough transform-based method for detecting lines.

Autonomous Positioning Techniques Based on Cramér-Rao Lower Bound Analysis

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Urruela Andreu

2006-01-01

Full Text Available We consider the problem of autonomously locating a number of asynchronous sensor nodes in a wireless network. A strong focus lies on reducing the processing resources needed to solve the relative positioning problem, an issue of great interest in resource-constrained wireless sensor networks. In the first part of the paper, based on a well-known derivation of the Cramér-Rao lower bound for the asynchronous sensor positioning problem, we are able to construct optimal preprocessing methods for sensor clock-offset cancellation. A cancellation of unknown clock-offsets from the asynchronous positioning problem reduces processing requirements, and, under certain reasonable assumptions, allows for statistically efficient distributed positioning algorithms. Cramér-Rao lower bound theory may also be used for estimating the performance of a positioning algorithm. In the second part of this paper, we exploit this property in developing a distributed algorithm, where the global positioning problem is solved suboptimally, using a divide-and-conquer approach of low complexity. The performance of this suboptimal algorithm is evaluated through computer simulation, and compared to previously published algorithms.

Summer Project on Exponential Convergence for IMC

Energy Technology Data Exchange (ETDEWEB)

Gentile, N [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2016-05-23

I want to look at modifying the Morel and Bolding algorithm in two ways. One is to remove the need to represent the intensity in a deterministic form and for a deterministic representation of a transport operator. The second is to look at representing the moments of the source with a simpler form that doesn’t require as many terms. Morel and Bolding also didn’t include scattering in their stuff. IMC has a lot of scattering occurring because of the effective scatters. I think that scattering can be added to the method, but I think that will require more than a summer’s worth of work. So we’ll just ignore scattering, and just look at problems with a huge c_v so that there is no effective scattering.

Summer Project on Exponential Convergence for IMC

International Nuclear Information System (INIS)

Gentile, N

2016-01-01

I want to look at modifying the Morel and Bolding algorithm in two ways. One is to remove the need to represent the intensity in a deterministic form and for a deterministic representation of a transport operator. The second is to look at representing the moments of the source with a simpler form that doesn't require as many terms. Morel and Bolding also didn't include scattering in their stuff. IMC has a lot of scattering occurring because of the effective scatters. I think that scattering can be added to the method, but I think that will require more than a summer's worth of work. So we'll just ignore scattering, and just look at problems with a huge c v so that there is no effective scattering.

Stabilization of Teleoperation Systems with Communication Delays: An IMC Approach

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Yuling Li

2018-01-01

Full Text Available The presence of time delays in communication introduces a limitation to the stability of bilateral teleoperation systems. This paper considers internal model control (IMC design of linear teleoperation system with time delays, and the stability of the closed-loop system is analyzed. It is shown that the stability is guaranteed delay-independently. The passivity assumption for external forces is removed for the proposed design of teleoperation systems. The behavior of the resulting teleoperation system is illustrated by simulations.

Influence of nanoparticle addition on the formation and growth of intermetallic compounds (IMCs) in Cu/Sn–Ag–Cu/Cu solder joint during different thermal conditions

International Nuclear Information System (INIS)

Ting Tan, Ai; Wen Tan, Ai; Yusof, Farazila

2015-01-01

Nanocomposite lead-free solders are gaining prominence as replacements for conventional lead-free solders such as Sn–Ag–Cu solder in the electronic packaging industry. They are fabricated by adding nanoparticles such as metallic and ceramic particles into conventional lead-free solder. It is reported that the addition of such nanoparticles could strengthen the solder matrix, refine the intermetallic compounds (IMCs) formed and suppress the growth of IMCs when the joint is subjected to different thermal conditions such as thermal aging and thermal cycling. In this paper, we first review the fundamental studies on the formation and growth of IMCs in lead-free solder joints. Subsequently, we discuss the effect of the addition of nanoparticles on IMC formation and their growth under several thermal conditions. Finally, an outlook on the future growth of research in the fabrication of nanocomposite solder is provided. (review)

Fisher Information and the Quantum Cramér-Rao Sensitivity Limit of Continuous Measurements

DEFF Research Database (Denmark)

Gammelmark, Søren; Mølmer, Klaus

2014-01-01

Precision measurements with quantum systems rely on our ability to trace the differences between experimental signals to variations in unknown physical parameters. In this Letter we derive the Fisher information and the ensuing Cramér-Rao sensitivity limit for parameter estimation by continuous...

Autoregressive Model with Partial Forgetting within Rao-Blackwellized Particle Filter

Czech Academy of Sciences Publication Activity Database

Dedecius, Kamil; Hofman, Radek

2012-01-01

Roč. 41, č. 5 (2012), s. 582-589 ISSN 0361-0918 R&D Projects: GA MV VG20102013018; GA ČR GA102/08/0567 Grant - others:ČVUT(CZ) SGS 10/099/OHK3/1T/16 Institutional research plan: CEZ:AV0Z10750506 Keywords : Bayesian methods * Particle filters * Recursive estimation Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 0.295, year: 2012 http://library.utia.cas.cz/separaty/2012/AS/dedecius-autoregressive model with partial forgetting within rao-blackwellized particle filter.pdf

Industrial hygiene survey. IMC, Agricultural Operation Division, Bartow, Florida

International Nuclear Information System (INIS)

Stephenson, F.; Cassady, M.

1977-10-01

An industrial hygiene survey was conducted at the Agricultural Operations Division, IMC, Bartow, Florida, on July 19-22, 1976, as part of the industry-wide study of the phosphate fertilizer industry. The phosphate ore mining operations, the plant, and the medical, safety, and industrial hygiene programs are described. The beneficiation plant was surveyed to determine the 8-hour time weighted averages of cadmium, chromium, vanadium, fluoride, arsenic, and silica. General area samples were taken for uranium and alpha-radiation. With the exception of uranium in the grinding area, all other elements analyzed came within the OSHA standards. However, several results exceed the NIOSH recommended standard

Influence of nanoparticle addition on the formation and growth of intermetallic compounds (IMCs) in Cu/Sn–Ag–Cu/Cu solder joint during different thermal conditions

Science.gov (United States)

Ting Tan, Ai; Wen Tan, Ai; Yusof, Farazila

2015-01-01

Nanocomposite lead-free solders are gaining prominence as replacements for conventional lead-free solders such as Sn–Ag–Cu solder in the electronic packaging industry. They are fabricated by adding nanoparticles such as metallic and ceramic particles into conventional lead-free solder. It is reported that the addition of such nanoparticles could strengthen the solder matrix, refine the intermetallic compounds (IMCs) formed and suppress the growth of IMCs when the joint is subjected to different thermal conditions such as thermal aging and thermal cycling. In this paper, we first review the fundamental studies on the formation and growth of IMCs in lead-free solder joints. Subsequently, we discuss the effect of the addition of nanoparticles on IMC formation and their growth under several thermal conditions. Finally, an outlook on the future growth of research in the fabrication of nanocomposite solder is provided. PMID:27877786

Establishment path and management innovation of mutually beneficial nonprofit organization (MBNPO: A study based on integrated marketing communications (IMC theory

Directory of Open Access Journals (Sweden)

Kwang-yong Shin

2017-05-01

Full Text Available Purpose - Research about the modern mutually beneficial nonprofit organizations (MBNPOs has great value because of the increasingly important role that the MBNPO plays in society. The establishment and management of MBNPOs are critical for its development. Design/methodology/approach - Integrated marketing communications (IMC theory is applied to the research on establishment and management innovation. The establishment of MBNPOs needs four sequential steps: identifying the target group, providing services to meet the demand of stakeholders, designing appropriate communication tactics and deploying proper organizational structure to accomplish efficient communication. Findings - Three types of approach enable traditional enterprises to transform into MBNPOs: product innovation, operational innovation and synergetic development. The application of IMC theory accomplishes management innovation of MBNPOs in three aspects: leading market-orientation specific to stakeholder-orientation, making management innovation systematic in MBNPOs and clarifying targets of management innovation in MBNPOs. Originality/value - This is one of the first examinations of establishment path and management innovation of MBNPO based on IMC theory.

Industrial hygiene survey. IMC, Phosphate Chemical Complex, New Wales, Florida

International Nuclear Information System (INIS)

Stephenson, F.; Cassady, M.

1977-10-01

An industrial hygiene survey was conducted by NIOSH at IMC Phosphate Chemical Complex, New Wales, Florida, on June 7-11, 1976, as part of a study of the phosphate industry. Phosphate fertilizer manufacturing, the plant, and the medical, safety, and industrial hygiene programs are described. During the study 8-hour time weighted averages were determined for exposure to arsenic, cadmium, chromium, vanadium, phosphoric acid, and sulfuric acid for workers involved in cleaning out phosphoric acid reactor vessels. General area samples were collected for fluorides, radon, and uranium. Several samples were above the NIOSH recommended levels for arsenic and chromium

On the Cramér–Rao bound applicability and the role of Fisher information in computational neuroscience

Czech Academy of Sciences Publication Activity Database

Pilarski, Stevan; Pokora, O.

2015-01-01

Roč. 136, Oct 2015 (2015), s. 11-22 ISSN 0303-2647 Institutional support: RVO:67985823 Keywords : Fisher information * neuronal coding * Cramér–Rao admissibility Subject RIV: BA - General Mathematics Impact factor: 1.495, year: 2015

The Bayesian Cramér-Rao lower bound in Astrometry

Science.gov (United States)

Mendez, R. A.; Echeverria, A.; Silva, J.; Orchard, M.

2018-01-01

A determination of the highest precision that can be achieved in the measurement of the location of a stellar-like object has been a topic of permanent interest by the astrometric community. The so-called (parametric, or non-Bayesian) Cramér-Rao (CR hereafter) bound provides a lower bound for the variance with which one could estimate the position of a point source. This has been studied recently by Mendez et al. (2013, 2014, 2015). In this work we present a different approach to the same problem (Echeverria et al. 2016), using a Bayesian CR setting which has a number of advantages over the parametric scenario.

Viscoelastic wormlike micelles formed by ionic liquid-type surfactant [C16imC8]Br towards template-assisted synthesis of CdS quantum dots.

Science.gov (United States)

Hu, Yimin; Han, Jie; Ge, Lingling; Guo, Rong

2018-01-31

In this paper, viscoelastic wormlike micelles consisting of cationic liquid-type surfactant, 1-hexadecyl-3-octyl imidazolium bromide ([C 16 imC 8 ]Br), water and different additives were utilized for the synthesis of CdS quantum dots. First, the influence of different additives, such as [Cd(NH 3 ) 6 ]Cl 2 and ethanethioamid (precursors for the synthesis of CdS quantum dots), and temperature on the viscoelasticity of the [C 16 imC 8 ]Br aqueous solution was studied by dynamic and steady rheology. Furthermore, the synthesized CdS quantum dots and their photoluminescence properties were characterized by transmission electron microscopy (TEM), UV-Vis absorption spectroscopy, X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDX). In the end, the mechanism for the synthesis of CdS quantum dots in [C 16 imC 8 ]Br wormlike micelles is proposed.

Limitations of Feedback, Feedforward and IMC Controller for a First Order Non-Linear Process with Dead Time

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Maruthai Suresh

2010-10-01

Full Text Available A nonlinear process, the heat exchanger whose parameters vary with respect to the process variable, is considered. The time constant and gain of the chosen process vary as a function of temperature. The limitations of the conventional feedback controller tuned using Ziegler-Nichols settings for the chosen process are brought out. The servo and regulatory responses through simulation and experimentation for various magnitudes of set-point changes and load changes at various operating points with the controller tuned only at a chosen nominal operating point are obtained and analyzed. Regulatory responses for output load changes are studied. The efficiency of feedforward controller and the effects of modeling error have been brought out. An IMC based system is presented to understand clearly how variations of system parameters affect the performance of the controller. The present work illustrates the effectiveness of Feedforward and IMC controller.

Enhanced IMC design of load disturbance rejection for integrating and unstable processes with slow dynamics.

Science.gov (United States)

Liu, Tao; Gao, Furong

2011-04-01

In view of the deficiencies in existing internal model control (IMC)-based methods for load disturbance rejection for integrating and unstable processes with slow dynamics, a modified IMC-based controller design is proposed to deal with step- or ramp-type load disturbance that is often encountered in engineering practices. By classifying the ways through which such load disturbance enters into the process, analytical controller formulae are correspondingly developed, based on a two-degree-of-freedom (2DOF) control structure that allows for separate optimization of load disturbance rejection from setpoint tracking. An obvious merit is that there is only a single adjustable parameter in the proposed controller, which in essence corresponds to the time constant of the closed-loop transfer function for load disturbance rejection, and can be monotonically tuned to meet a good trade-off between disturbance rejection performance and closed-loop robust stability. At the same time, robust tuning constraints are given to accommodate process uncertainties in practice. Illustrative examples from the recent literature are used to show effectiveness and merits of the proposed method for different cases of load disturbance. Copyright © 2010. Published by Elsevier Ltd.

Design of an Image Motion Compenstaion (IMC Algorithm for Image Registration of the Communication, Ocean, Meteorolotical Satellite (COMS-1

Directory of Open Access Journals (Sweden)

Taek Seo Jung

2006-03-01

Full Text Available This paper presents an Image Motion Compensation (IMC algorithm for the Korea's Communication, Ocean, and Meteorological Satellite (COMS-1. An IMC algorithm is a priority component of image registration in Image Navigation and Registration (INR system to locate and register radiometric image data. Due to various perturbations, a satellite has orbit and attitude errors with respect to a reference motion. These errors cause depointing of the imager aiming direction, and in consequence cause image distortions. To correct the depointing of the imager aiming direction, a compensation algorithm is designed by adapting different equations from those used for the GOES satellites. The capability of the algorithm is compared with that of existing algorithm applied to the GOES's INR system. The algorithm developed in this paper improves pointing accuracy by 40%, and efficiently compensates the depointings of the imager aiming direction.

Gating Techniques for Rao-Blackwellized Monte Carlo Data Association Filter

Directory of Open Access Journals (Sweden)

Yazhao Wang

2014-01-01

Full Text Available This paper studies the Rao-Blackwellized Monte Carlo data association (RBMCDA filter for multiple target tracking. The elliptical gating strategies are redesigned and incorporated into the framework of the RBMCDA filter. The obvious benefit is the reduction of the time cost because the data association procedure can be carried out with less validated measurements. In addition, the overlapped parts of the neighboring validation regions are divided into several separated subregions according to the possible origins of the validated measurements. In these subregions, the measurement uncertainties can be taken into account more reasonably than those of the simple elliptical gate. This would help to achieve higher tracking ability of the RBMCDA algorithm by a better association prior approximation. Simulation results are provided to show the effectiveness of the proposed gating techniques.

Particle rejuvenation of Rao-Blackwellized sequential Monte Carlo smoothers for conditionally linear and Gaussian models

Science.gov (United States)

Nguyen, Ngoc Minh; Corff, Sylvain Le; Moulines, Éric

2017-12-01

This paper focuses on sequential Monte Carlo approximations of smoothing distributions in conditionally linear and Gaussian state spaces. To reduce Monte Carlo variance of smoothers, it is typical in these models to use Rao-Blackwellization: particle approximation is used to sample sequences of hidden regimes while the Gaussian states are explicitly integrated conditional on the sequence of regimes and observations, using variants of the Kalman filter/smoother. The first successful attempt to use Rao-Blackwellization for smoothing extends the Bryson-Frazier smoother for Gaussian linear state space models using the generalized two-filter formula together with Kalman filters/smoothers. More recently, a forward-backward decomposition of smoothing distributions mimicking the Rauch-Tung-Striebel smoother for the regimes combined with backward Kalman updates has been introduced. This paper investigates the benefit of introducing additional rejuvenation steps in all these algorithms to sample at each time instant new regimes conditional on the forward and backward particles. This defines particle-based approximations of the smoothing distributions whose support is not restricted to the set of particles sampled in the forward or backward filter. These procedures are applied to commodity markets which are described using a two-factor model based on the spot price and a convenience yield for crude oil data.

A Cramer Rao analysis on receiver placement in a FM band commensal radar system based on doppler only measurements

CSIR Research Space (South Africa)

Maasdorp, FDV

2014-10-01

Full Text Available of receiver positions. Further, we show that time history information of a target can cumulatively be used together with FIM that will improve the Cramer-Rao bound. Lastly, we use the theory developed to evaluate receiver placement combinations by means of a...

Design and construction of demineralized water production and maintenance system for RA-O nuclear reactor

International Nuclear Information System (INIS)

Rumis, D.; Martin, H.R.

1990-01-01

The normal operation of zero power RA-O Nuclear Reactor requires a production and maintenance of demineralized water system. This system was designed and built-up during the works for actualization, upgrading and new start up at Cordoba National University of this facility. This paper comments the relevant aspects about the didactical purpose of that system and the details considered for training and practices with it. Similarly, considerations about solids wastes and effluents treatment are discussed. (Author)

Integrated Marketing Communications (IMC) Variables That Influence Perceived Return on Investment (ROI) in Higher Education: Chief Marketing Officers' Perceptions

Science.gov (United States)

King, Adrienne L.

2013-01-01

This study examines the relationship of the level of Integrated Marketing Communications (IMC) implementation, level of open systems and change in state appropriations on perceived return on investment (ROI) in U.S. public higher education institutions (HEIs). Designed to provide HEI leaders with data to more accurately determine the best IMC…

Scientific Opinion on the substantiation of a health claim related to SYNBIO®, a combination of Lactobacillus rhamnosus IMC 501® and Lactobacillus paracasei IMC 502®, and maintenance of normal defecation pursuant to Article 13(5) of Regulation (EC) No

DEFF Research Database (Denmark)

Tetens, Inge

2015-01-01

Following an application from Synbiotec S.r.l., submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the s......Following an application from Synbiotec S.r.l., submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion...... on the scientific substantiation of a health claim related to SYNBIO®, a combination of Lactobacillus rhamnosus IMC 501® and Lactobacillus paracasei IMC 502®, and maintenance of normal defecation. The Panel considers that the food, SYNBIO®, which is the subject of the health claim, is sufficiently characterised...... that no evidence was provided that the tools used to assess changes in bowel habits in response to an intervention were valid. Therefore, no conclusions could be drawn from these studies for the scientific substantiation of a claim on SYNBIO® and maintenance of normal defecation. In the absence of evidence...

Inertial Microfluidic Cell Stretcher (iMCS): Fully Automated, High-Throughput, and Near Real-Time Cell Mechanotyping.

Science.gov (United States)

Deng, Yanxiang; Davis, Steven P; Yang, Fan; Paulsen, Kevin S; Kumar, Maneesh; Sinnott DeVaux, Rebecca; Wang, Xianhui; Conklin, Douglas S; Oberai, Assad; Herschkowitz, Jason I; Chung, Aram J

2017-07-01

Mechanical biomarkers associated with cytoskeletal structures have been reported as powerful label-free cell state identifiers. In order to measure cell mechanical properties, traditional biophysical (e.g., atomic force microscopy, micropipette aspiration, optical stretchers) and microfluidic approaches were mainly employed; however, they critically suffer from low-throughput, low-sensitivity, and/or time-consuming and labor-intensive processes, not allowing techniques to be practically used for cell biology research applications. Here, a novel inertial microfluidic cell stretcher (iMCS) capable of characterizing large populations of single-cell deformability near real-time is presented. The platform inertially controls cell positions in microchannels and deforms cells upon collision at a T-junction with large strain. The cell elongation motions are recorded, and thousands of cell deformability information is visualized near real-time similar to traditional flow cytometry. With a full automation, the entire cell mechanotyping process runs without any human intervention, realizing a user friendly and robust operation. Through iMCS, distinct cell stiffness changes in breast cancer progression and epithelial mesenchymal transition are reported, and the use of the platform for rapid cancer drug discovery is shown as well. The platform returns large populations of single-cell quantitative mechanical properties (e.g., shear modulus) on-the-fly with high statistical significances, enabling actual usages in clinical and biophysical studies. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Fungal Nomenclature at IMC10: Report of the Nomenclature Sessions.

Science.gov (United States)

Redhead, Scott A; Demoulin, Vincent; Hawksworth, David L; Seifert, Keith A; Turland, Nicholas J

2014-12-01

Three Nomenclature Sessions were convened during the 10(th) International Mycological Congress (IMC10) in Bangkok on 3-8 August 2014. In addition a Questionnaire was given to all delegates. This Report reviews and summarizes the views expressed in the Sessions and in the responses to the Questionnaire. The issues covered related to aspects of: registration, protected names, forgotten names, pleomorphic fungi, lichenized fungi, typification, diagnoses, and governance. In addition, reports were received from working groups preparing lists of names to be proposed for protection, and controversial cases of competing names were discussed. The Congress was mandated to ratify decisions of the Nomenclature Committee for Fungi (NCF) on the appointment of repositories for the registration of new fungal names. After discussion in the Sessions on the decision of the NCF to appoint three such bodies, a Resolution to that effect was approved by the Congress. The Congress also adopted a Resolution asking that the opinions of mycologists on future directions for the nomenclature of fungi be taken into account in formulating changes in the rules for consideration at the International Botanical Congress in 2017.

Combined state and parameter identification of nonlinear structural dynamical systems based on Rao-Blackwellization and Markov chain Monte Carlo simulations

Science.gov (United States)

Abhinav, S.; Manohar, C. S.

2018-03-01

The problem of combined state and parameter estimation in nonlinear state space models, based on Bayesian filtering methods, is considered. A novel approach, which combines Rao-Blackwellized particle filters for state estimation with Markov chain Monte Carlo (MCMC) simulations for parameter identification, is proposed. In order to ensure successful performance of the MCMC samplers, in situations involving large amount of dynamic measurement data and (or) low measurement noise, the study employs a modified measurement model combined with an importance sampling based correction. The parameters of the process noise covariance matrix are also included as quantities to be identified. The study employs the Rao-Blackwellization step at two stages: one, associated with the state estimation problem in the particle filtering step, and, secondly, in the evaluation of the ratio of likelihoods in the MCMC run. The satisfactory performance of the proposed method is illustrated on three dynamical systems: (a) a computational model of a nonlinear beam-moving oscillator system, (b) a laboratory scale beam traversed by a loaded trolley, and (c) an earthquake shake table study on a bending-torsion coupled nonlinear frame subjected to uniaxial support motion.

Correlação entre Índice de massa Corporal (IMC pré-natal e peso ao nascer – um estudo longitudinal - doi: 10.5020/18061230.2012.p356

Directory of Open Access Journals (Sweden)

Saurabh Rambiharilal Shrivastava

2012-11-01

Full Text Available Objetivos: Estudar a correlação entre Índice de Massa Corporal (IMC no período pré-natal e o peso de nascimento da criança, bem como, os determinantes sócio-demográficos de peso ao nascer. Métodos: Um estudo longitudinal de um ano de duração, de junho 2010 a maio de 2011, foi realizado em uma favela urbana de Mumbai, Índia. O método de amostragem universal foi aplicado, incluindo como sujeitos todas as mulheres grávidas que realizaram pré-natal com, no mínimo, duas visitas, incluindo pelo menos uma no terceiro trimestre, registradas no centro urbano de saúde, de junho a agosto de 2010. Mulheres com qualquer estado mórbido pré-existente ou com histórico de gestações com nascimento de gêmeos ou de criança com qualquer má-formação congênita, ou inda, com ocorrência de natimorto ou parto em casa, foram excluídas do estudo. Estas mulheres foram acompanhadas durante os próximos meses até o parto. O peso materno foi medido em cada visita e calculado o IMC, ou o IMC médio, no caso de mais de uma visita em qualquer trimestre. O peso ao nascer foi registrado a partir de dados do hospital ou maternidade. Resultados: A prevalência de Baixo Peso ao Nascer (BPN foi de 26,7%. Correlação entre o IMCmaterno do terceiro trimestre e o peso ao nascer foi moderadamente positiva. 60,8% da variabilidade no peso ao nascer podem ser preditos pelo IMC materno no terceiro trimestre. Conclusão: O IMC materno no terceiro trimestre pode ser usado como um preditor de peso ao nascimento neonatal. Informação, Educação e Aconselhamento (IEC sobre a utilização do pré-natal podem ajudar na redução da incidência de Baixo Peso ao Nascer (BPN.

Relacion entre capacidades físicas, índice de masa corporal (IMC) y la discriminación dentro de la clase de Educación Física en alumnos de 10 y 11 años, en cuatro colegios de Chillan, Chile

OpenAIRE

Portes Júnior, Moacyr; Avendaño R., Macarena; Baeza, Daniela G.; Castillo E., Gabriela; Cifuentes A., Claudio; Moraga M., Rodrigo

2013-01-01

Objetivo: verificar relación entre IMC, capacidades físicas y discriminación en clase de Educación Física, alumnos entre 10 a 11 años, 4 colegios de Chillán, Chile. Metodología: medir flexibilidad, velocidad y resistencia; calcular IMC; posteriormente contestar cuestionario de auto percepción frente a sus pares en relación a discriminación en clases de Educación Física. Población: 178 sujetos; muestra: 44 indicaron discriminación. Resultados: IMC: 72,6% de la muestra, que sienten discriminaci...

Correlação entre o índice de massa corporal (IMC de gestantes e hipotensão após raquianestesia para cesarianas

Directory of Open Access Journals (Sweden)

Fernando Souza Nani

2011-02-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: Existem poucas publicações correlacionando hipotensão em gestantes obesas, principalmente em obesas mórbidas, após raquianestesia para cesárea. Objetivamos avaliar a incidência de hipotensão correlacionada ao IMC. MÉTODO: No grupo Eutrofia foram incluídas 49 pacientes com IMC pré-gestacional abaixo de 25 kg.m-2 e no grupo Sobrepeso, 51 pacientes com IMC igual ou acima de 25 kg.m-2. Após raquianestesia, foram anotadas as medidas de pressão arterial, volume de cristaloides infundidos e dose de vasopressores utilizada até o nascimento. Redução da pressão arterial sistólica abaixo de 100 mmHg ou 10% da pressão arterial sistólica (PAS inicial foi classificada como hipotensão e corrigida com vasopressor. RESULTADOS: Os episódios de hipotensão foram menores no grupo Eutrofia (5,89 ± 0,53 vs. 7,80 ± 0,66; p = 0,027, assim como a quantidade de cristaloides (1.298 ± 413,6 mL vs. 1.539 ± 460,0 mL; p = 0,007 e o uso de vasopressores (5,87 ± 3,45 bolus vs. 7,70 ± 4,46 bolus; p = 0,023. Quanto às doenças associadas, observamos maior incidência de diabetes entre as gestantes obesas (29,41% vs. 9,76%, RR 1,60; IC 95%: 1,15-2,22; p = 0,036, porém não houve diferença entre os grupos em relação à incidência de doença hipertensiva específica da gestação (DHEG (sobrepeso: 21,57%, peso normal: 12,20%, RR 1,30; IC 95%: 0,88-1,94; p = 0,28. CONCLUSÕES: Na amostra estudada, IMC pré-gestacional maior ou igual a 25 kg.m-2 apresentou-se como fator de risco para hipotensão após raquianestesia em pacientes submetidas a cesáreas. O mesmo grupo de pacientes necessitou de um número de doses maior de vasopressores. A valorização desses achados implica aprimorar as técnicas anestésicas nessas pacientes a fim de diminuir as consequências da hipotensão pós-raquianestesia, tanto na gestante como no feto.

Practitioners’ view of the role of OOH advertising media in IMC campaigns

Directory of Open Access Journals (Sweden)

A. Therese Roux

2016-12-01

Full Text Available Despite the traction that contemporary out-of-home advertising has gained in the global media landscape, there are still some ambiguities regarding the contribution of this medium in the context of integrated marketing communication. Previous studies have examined consumers’ responses to different out-of-home advertising media types; however, little attention has been paid to how they could contribute to an overall integrated marketing communication (IMC program. The purpose of the study was, therefore, to explore a practitioner’s view of the role of out-of-home advertising media in an integrated marketing communication campaign. Investigating knowledgeable practitioners’ perspectives and practices helped to reveal novel media planning techniques applied by specialists in the field and contributed to the limited theory on out-of-home advertising media planning. The three roles performed by out-of-home advertising media within this context: support; lead; or even as the only media, were clarified. Some unique media tactics to reach marketing communication objectives on cognitive, affective or behavioural levels and direction for future research were also proposed.

Purification, crystallization and preliminary X-ray diffraction analysis of inner membrane complex (IMC) subcompartment protein 1 (ISP1) from Toxoplasma gondii

International Nuclear Information System (INIS)

Tonkin, Michelle L.; Brown, Shannon; Beck, Josh R.; Bradley, Peter J.; Boulanger, Martin J.

2012-01-01

To characterize the ISP family of proteins present in apicomplexan parasites, ISP1 from T. gondii was expressed, purified and crystallized. Two crystal forms (cubic and orthorhombic) were analyzed by X-ray diffraction and data were processed to 2.05 and 2.1 Å resolution, respectively. The protozoan parasites of the Apicomplexa phylum are devastating global pathogens. Their success is largely due to phylum-specific proteins found in specialized organelles and cellular structures. The inner membrane complex (IMC) is a unique apicomplexan structure that is essential for motility, invasion and replication. The IMC subcompartment proteins (ISP) have recently been identified in Toxoplasma gondii and shown to be critical for replication, although their specific mechanisms are unknown. Structural characterization of TgISP1 was pursued in order to identify the fold adopted by the ISPs and to generate detailed insight into how this family of proteins functions during replication. An N-terminally truncated form of TgISP1 was purified from Escherichia coli, crystallized and subjected to X-ray diffraction analysis. Two crystal forms of TgISP1 belonging to space groups P4 1 32 or P4 3 32 and P2 1 2 1 2 1 diffracted to 2.05 and 2.1 Å resolution, respectively

Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vector

Directory of Open Access Journals (Sweden)

Cronin Michael

2008-06-01

Full Text Available Abstract Background The foodborne, gram-positive pathogen, Listeria monocytogenes, is capable of causing lethal infections in compromised individuals. In the post genomic era of L. monocytogenes research, techniques are required to identify and validate genes involved in the pathogenicity and environmental biology of the organism. The aim here was to develop a widely applicable method to tag L. monocytogenes strains, with a particular emphasis on the development of multiple strain competitive index assays. Results We have constructed a new site-specific integrative vector, pIMC, based on pPL2, for the selection of L. monocytogenes from complex samples. The pIMC vector was further modified through the incorporation of IPTG inducible markers (antibiotic and phenotypic to produce a suite of four vectors which allowed the discrimination of multiple strains from a single sample. We were able to perform murine infection studies with up to four EGDe isolates within a single mouse and showed that the tags did not impact upon growth rate or virulence. The system also allowed the identification of subtle differences in virulence between strains of L. monocytogenes commonly used in laboratory studies. Conclusion This study has developed a competitive index assay that can be broadly applied to all L. monocytogenes strains. Improved statistical robustness of the data was observed, resulting in fewer mice being required for virulence assays. The competitive index assays provide a powerful method to analyse the virulence or fitness of L. monocytogenes in complex biological samples.

Novel Mobile Robot Simultaneous Localization and Mapping Using Rao-Blackwellised Particle Filter

Directory of Open Access Journals (Sweden)

Hong Bingrong

2008-11-01

Full Text Available This paper presents the novel method of mobile robot simultaneous localization and mapping (SLAM, which is implemented by using the Rao-Blackwellised particle filter (RBPF for monocular vision-based autonomous robot in unknown indoor environment. The particle filter is combined with unscented Kalman filter (UKF to extending the path posterior by sampling new poses that integrate the current observation. The landmark position estimation and update is implemented through the unscented transform (UT. Furthermore, the number of resampling steps is determined adaptively, which seriously reduces the particle depletion problem. Monocular CCD camera mounted on the robot tracks the 3D natural point landmarks, which are structured with matching image feature pairs extracted through Scale Invariant Feature Transform (SIFT. The matching for multi-dimension SIFT features which are highly distinctive due to a special descriptor is implemented with a KDTree in the time cost of O(log2N. Experiments on the robot Pioneer3 in our real indoor environment show that our method is of high precision and stability.

Novel Mobile Robot Simultaneous Loclization and Mapping Using Rao-Blackwellised Particle Filter

Directory of Open Access Journals (Sweden)

Li Maohai

2006-09-01

Full Text Available This paper presents the novel method of mobile robot simultaneous localization and mapping (SLAM, which is implemented by using the Rao-Blackwellised particle filter (RBPF for monocular vision-based autonomous robot in unknown indoor environment. The particle filter is combined with unscented Kalman filter (UKF to extending the path posterior by sampling new poses that integrate the current observation. The landmark position estimation and update is implemented through the unscented transform (UT. Furthermore, the number of resampling steps is determined adaptively, which seriously reduces the particle depletion problem. Monocular CCD camera mounted on the robot tracks the 3D natural point landmarks, which are structured with matching image feature pairs extracted through Scale Invariant Feature Transform (SIFT. The matching for multi-dimension SIFT features which are highly distinctive due to a special descriptor is implemented with a KD-Tree in the time cost of O(log2N. Experiments on the robot Pioneer3 in our real indoor environment show that our method is of high precision and stability.

Imagen corporal, funcionamiento sexual y autoestima en mujeres brasileñas con un Índice de Masa Corporal (IMC) elevado

OpenAIRE

Santos Silva, Ajurymar; Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut

2015-01-01

En la sociedad brasileña, el `culto al cuerpo` es una práctica común y diseminada entre las mujeres. El objetivo general de la investigación es analizar si las puntuaciones del Índice de Masa Corporal (IMC), de mujeres brasileñas, interfieren en los niveles de satisfacción corporal (imagen corporal), funcionamiento sexual y autoestima. El diseño fue cuantitativo, y se han empleado cuatro instrumentos distintos, en una muestra de 102 mujeres brasileñas. Los cuestionarios utilizados fueron: un ...

The influence of random element displacement on DOA estimates obtained with (Khatri-Rao-)root-MUSIC.

Science.gov (United States)

Inghelbrecht, Veronique; Verhaevert, Jo; van Hecke, Tanja; Rogier, Hendrik

2014-11-11

Although a wide range of direction of arrival (DOA) estimation algorithms has been described for a diverse range of array configurations, no specific stochastic analysis framework has been established to assess the probability density function of the error on DOA estimates due to random errors in the array geometry. Therefore, we propose a stochastic collocation method that relies on a generalized polynomial chaos expansion to connect the statistical distribution of random position errors to the resulting distribution of the DOA estimates. We apply this technique to the conventional root-MUSIC and the Khatri-Rao-root-MUSIC methods. According to Monte-Carlo simulations, this novel approach yields a speedup by a factor of more than 100 in terms of CPU-time for a one-dimensional case and by a factor of 56 for a two-dimensional case.

Implementation of Information Management System for Radiation Safety of Personnel at the Russian Northwest Center for Radioactive Waste Management 'SevRAO' - 13131

Energy Technology Data Exchange (ETDEWEB)

Chizhov, K.; Simakov, A.; Seregin, V.; Kudrin, I.; Shandala, N.; Tsovyanov, A.; Kryuchkov, V. [Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, RF Ministry of Health and Social Development. 46, Zhivopisnaya St., Moscow, 123182 (Russian Federation); Krasnoschekov, A.; Kosnikov, A. [Northwest Center for Radioactive Waste Management ' SevRAO' - a branch of the Federal State Unitary Enterprise ' Enterprise for Radioactive Waste Management' ' RosRAO' 183017, Murmansk, Lobova st., 100 (Russian Federation); Kemsky, I. [Regional management - 120 of the Federal Medical-Biological Agency, 184682, Snezhnogorsk, Valentina Biryukova St., 5/1 (Russian Federation); Sneve, M. [Norwegian Radiation Protection Authority, Postboks 55, 1332 Oesteraas (Norway)

2013-07-01

The report is an overview of the information-analytical system designed to assure radiation safety of workers. The system was implemented in the Northwest Radioactive Waste Management Center 'SevRAO' (which is a branch of the Federal State Unitary Enterprise 'Radioactive Waste Management Enterprise RosRAO'). The center is located in the Northwest Russia. In respect to 'SevRAO', the Federal Medical-Biological Agency is the regulatory body, which deals with issues of radiation control. The main document to regulate radiation control is 'Reference levels of radiation factors in radioactive wastes management center'. This document contains about 250 parameters. We have developed a software tool to simplify control of these parameters. The software includes: input interface, the database, dose calculating module and analytical block. Input interface is used to enter radiation environment data. Dose calculating module calculates the dose on the route. Analytical block optimizes and analyzes radiation situation maps. Much attention is paid to the GUI and graphical representation of results. The operator can enter the route at the industrial site or watch the fluctuations of the dose rate field on the map. Most of the results are presented in a visual form. Here we present some analytical tasks, such as comparison of the dose rate in some point with control levels at this point, to be solved for the purpose of radiation safety control. The program helps to identify points making the largest contribution to the collective dose of the personnel. The tool can automatically calculate the route with the lowest dose, compare and choose the best route. The program uses several options to visualize the radiation environment at the industrial site. This system will be useful for radiation monitoring services during the operation, planning of works and development of scenarios. The paper presents some applications of this system on real data

Rao-Blackwellization for Adaptive Gaussian Sum Nonlinear Model Propagation

Science.gov (United States)

Semper, Sean R.; Crassidis, John L.; George, Jemin; Mukherjee, Siddharth; Singla, Puneet

2015-01-01

each component weight during the nonlinear propagation stage an approximation of the true pdf can be successfully reconstructed. Particle filtering (PF) methods have gained popularity recently for solving nonlinear estimation problems due to their straightforward approach and the processing capabilities mentioned above. The basic concept behind PF is to represent any pdf as a set of random samples. As the number of samples increases, they will theoretically converge to the exact, equivalent representation of the desired pdf. When the estimated qth moment is needed, the samples are used for its construction allowing further analysis of the pdf characteristics. However, filter performance deteriorates as the dimension of the state vector increases. To overcome this problem Ref. [5] applies a marginalization technique for PF methods, decreasing complexity of the system to one linear and another nonlinear state estimation problem. The marginalization theory was originally developed by Rao and Blackwell independently. According to Ref. [6] it improves any given estimator under every convex loss function. The improvement comes from calculating a conditional expected value, often involving integrating out a supportive statistic. In other words, Rao-Blackwellization allows for smaller but separate computations to be carried out while reaching the main objective of the estimator. In the case of improving an estimator's variance, any supporting statistic can be removed and its variance determined. Next, any other information that dependents on the supporting statistic is found along with its respective variance. A new approach is developed here by utilizing the strengths of the adaptive Gaussian sum propagation in Ref. [2] and a marginalization approach used for PF methods found in Ref. [7]. In the following sections a modified filtering approach is presented based on a special state-space model within nonlinear systems to reduce the dimensionality of the optimization problem in

Reaching the Quantum Cramér-Rao Bound for Transmission Measurements

Science.gov (United States)

Woodworth, Timothy; Chan, Kam Wai Clifford; Marino, Alberto

2017-04-01

The quantum Cramér-Rao bound (QCRB) is commonly used to quantify the lower bound for the uncertainty in the estimation of a given parameter. Here, we calculate the QCRB for transmission measurements of an optical system probed by a beam of light. Estimating the transmission of an optical element is important as it is required for the calibration of optimal states for interferometers, characterization of high efficiency photodetectors, or as part of other measurements, such as those in plasmonic sensors or in ellipsometry. We use a beam splitter model for the losses introduced by the optical system to calculate the QCRB for different input states. We compare the bound for a coherent state, a two-mode squeezed-state (TMSS), a single-mode squeezed-state (SMSS), and a Fock state and show that it is possible to obtain an ultimate lower bound, regardless of the state used to probe the system. We prove that the Fock state gives the lowest possible uncertainty in estimating the transmission for any state and demonstrate that the TMSS and SMSS approach this ultimate bound for large levels of squeezing. Finally, we show that a simple measurement strategy for the TMSS, namely an intensity difference measurement, is able to saturate the QCRB. Work supported by the W.M. Keck Foundation.

Optimizing wavelength choice for quantitative optoacoustic imaging using the Cramer-Rao lower bound

International Nuclear Information System (INIS)

Modgil, Dimple; La Riviere, Patrick J

2010-01-01

Several papers have recently addressed the issue of estimating chromophore concentration in optoacoustic imaging (OAI) using multiple wavelengths. The choice of wavelengths obviously affects the accuracy and precision of the estimates. One might assume that the wavelengths that maximize the extinction coefficients of the chromophores would be the most suitable. However, this may not always be the case since the distribution of light intensity in the medium is also wavelength dependent. In this paper, we explore a method for optimizing the choice of wavelengths based on the Cramer-Rao lower bound (CRLB) on the variance of the chromophore concentration. This lower bound on variance can be evaluated numerically for different wavelengths using the variation of the extinction coefficients and scattering coefficients with wavelength. The wavelengths that give the smallest variance will be considered optimal for multi-wavelength OAI to estimate the chromophore concentrations. The expression for the CRLB has been derived analytically for estimating the concentration of multiple chromophores for several simple phantom models for the case when the optoacoustic signal is proportional to the product of the optical absorption and the illumination function. This approach could be easily extended to other geometries.

Optimizing wavelength choice for quantitative optoacoustic imaging using the Cramer-Rao lower bound.

Science.gov (United States)

Modgil, Dimple; La Riviére, Patrick J

2010-12-07

Several papers have recently addressed the issue of estimating chromophore concentration in optoacoustic imaging (OAI) using multiple wavelengths. The choice of wavelengths obviously affects the accuracy and precision of the estimates. One might assume that the wavelengths that maximize the extinction coefficients of the chromophores would be the most suitable. However, this may not always be the case since the distribution of light intensity in the medium is also wavelength dependent. In this paper, we explore a method for optimizing the choice of wavelengths based on the Cramer-Rao lower bound (CRLB) on the variance of the chromophore concentration. This lower bound on variance can be evaluated numerically for different wavelengths using the variation of the extinction coefficients and scattering coefficients with wavelength. The wavelengths that give the smallest variance will be considered optimal for multi-wavelength OAI to estimate the chromophore concentrations. The expression for the CRLB has been derived analytically for estimating the concentration of multiple chromophores for several simple phantom models for the case when the optoacoustic signal is proportional to the product of the optical absorption and the illumination function. This approach could be easily extended to other geometries.

Quantum Cramer–Rao Bound for a Massless Scalar Field in de Sitter Space

Directory of Open Access Journals (Sweden)

Marcello Rotondo

2017-10-01

Full Text Available How precisely can we estimate cosmological parameters by performing a quantum measurement on a cosmological quantum state? In quantum estimation theory, the variance of an unbiased parameter estimator is bounded from below by the inverse of measurement-dependent Fisher information and ultimately by quantum Fisher information, which is the maximization of the former over all positive operator-valued measurements. Such bound is known as the quantum Cramer –Rao bound. We consider the evolution of a massless scalar field with Bunch–Davies vacuum in a spatially flat FLRW spacetime, which results in a two-mode squeezed vacuum out-state for each field wave number mode. We obtain the expressions of the quantum Fisher information as well as the Fisher informations associated to occupation number measurement and power spectrum measurement, and show the specific results of their evolution for pure de Sitter expansion and de Sitter expansion followed by a radiation-dominated phase as examples. We will discuss these results from the point of view of the quantum-to-classical transition of cosmological perturbations and show quantitatively how this transition and the residual quantum correlations affect the bound on the precision.

Enhanced IMC based PID controller design for non-minimum phase (NMP) integrating processes with time delays.

Science.gov (United States)

Ghousiya Begum, K; Seshagiri Rao, A; Radhakrishnan, T K

2017-05-01

Internal model control (IMC) with optimal H 2 minimization framework is proposed in this paper for design of proportional-integral-derivative (PID) controllers. The controller design is addressed for integrating and double integrating time delay processes with right half plane (RHP) zeros. Blaschke product is used to derive the optimal controller. There is a single adjustable closed loop tuning parameter for controller design. Systematic guidelines are provided for selection of this tuning parameter based on maximum sensitivity. Simulation studies have been carried out on various integrating time delay processes to show the advantages of the proposed method. The proposed controller provides enhanced closed loop performances when compared to recently reported methods in the literature. Quantitative comparative analysis has been carried out using the performance indices, Integral Absolute Error (IAE) and Total Variation (TV). Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

Associação entre IMC e teste de coordenação corporal para crianças (KTK. Uma meta-análise

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Leonardo Gomes de Oliveira Luz

2015-06-01

Full Text Available O Teste de Coordenação Corporal para Crianças (Körperkoordinationstest für Kinder, KTK tem sido utilizado na avaliação da coordenação motora de crianças e adolescentes. O objetivo desta revisão sistemática com meta-análise foi analisar a relação entre o índice de massa corporal (IMC e o desempenho motor no KTK em crianças e jovens escolares saudáveis. O estudo baseou-se em pesquisas indexadas nas bases eletrônicas PubMed e SciELO. Os descritores foram: "Körperkoordinationstest für Kinder" e "KTK". Foram considerados artigos em inglês e português publicados até Outubro de 2014. A qualidade dos estudos foi determinada pelas Escalas PEDro e STROBE. Foi realizada meta-análise utilizando o software Comprehensive Meta-Analysis V2. Foram incluídos 10 estudos. O resultado global com base no modelo de efeitos fixos mostrou que valores maiores de IMC estão diretamente associados ao baixo desempenho no KTK. Apesar da pequena diferença entre ambos, a magnitude do efeito da associação foi classificada como pequena, porém, significativa para o sexo masculino (r=0,29; IC95% 0,27 a 0,32; Z=22,47; p=0,000 e moderada para o sexo feminino (r=0,32; IC95% 0,30 a 0,34; Z=24,76; p=0,000. Os estudos apresentaram características amostrais bastante divergentes quanto ao tamanho da amostra e a faixa etária dos sujeitos, além de nenhum deles ter analisado o estado maturacional dos participantes. Conclui-se que há uma tendência de relação positiva entre valores elevados de IMC e o baixo desempenho no KTK. Para confirmação desta tendência, recomenda-se que os próximos trabalhos considerem o estado maturacional dos participantes, além de possibilitarem uma análise por sexo e idade.

The Fisher-information-based uncertainty relation, Cramer-Rao inequality and kinetic energy for the D-dimensional central problem

Energy Technology Data Exchange (ETDEWEB)

Dehesa, J S [Departamento de Fisica Atomica, Molecular y Nuclear, Universidad de Granada, 18071-Granada (Spain); Gonzalez-Ferez, R [Departamento de Fisica Atomica, Molecular y Nuclear, Universidad de Granada, 18071-Granada (Spain); Sanchez-Moreno, P [Departamento de Fisica Atomica, Molecular y Nuclear, Universidad de Granada, 18071-Granada (Spain)

2007-02-23

The inequality >= (l+1/2){sup 2}, with L being the grand orbital quantum number, and its conjugate relation for ((r{sup 2}) (p{sup -2})) are shown to be fulfilled in the D-dimensional central problem. Their use has allowed us to improve the Fisher-information-based uncertainty relation (I{sub {rho}}I{sub {gamma}}{>=} const) and the Cramer-Rao inequalities ((r{sup 2})I{sub {rho}} {>=} D{sup 2}; (p{sup 2})I{sub {gamma}} {>=} D{sup 2}). In addition, the kinetic energy and the radial expectation value (r{sup 2}) are shown to be bounded from below by the Fisher information in position and momentum spaces, denoted by I{sub {rho}} and I{sub {gamma}}, respectively.

Travel report on a preparatory mission to the Agencija RAO, Ljubljana for a radium conditioning operation

International Nuclear Information System (INIS)

Neubauer, J.

2001-07-01

The purpose of the trip was to establish the current status of radioactive waste management in Slovenia, to discuss their plans for the future management of their radioactive wastes and to prepare for a radium source conditioning operation to make safe and secure their known inventory of radium withdrawn from service. The IAEA are considering placing a contract on the Oesterreichisches Forschungszentrum Seibersdorf (OeFZS) to carry out the radium conditioning operation on the agency's behalf in a manner used successfully on a number of previous occasions. In Slovenia responsibility for the management of radioactive wastes arising from nuclear applications in medicine research and industry is delegated to 'Agencija Rao'. First a visit was made to the storage building in which such wastes are stored, the building being within the grounds of the Josef Stefan Institute in Ljubljana. The possibility of carrying out the radium conditioning operation in the building and the improvements and modifications necessary was discussed. The inventory of stored waste was reviewed, the packages containing radium were identified and located in the store. Some of these contained radium-beryllium sources. It was agreed that such sources would not be conditioned during the forthcoming operation. Next a visit was made to the chemistry laboratories of the Josef Stefan Institute, these being a possible alternative location for the operation. On returning to the 'Agencija Rao' office in Ljubljana detail discussion of the merits of the alternative locations were discussed. It was realized that the operation could proceed quicker and at less cost if the existing laboratory was chosen, the unknown factor is the time taken to obtain regulatory approval. Next detailed discussion took place of the availability of necessary equipment and consumable items and agreement reached on what should be supplied locally and what should be brought to Slovenia, by the conditioning team. Plans were made to

Optimization of source and detector configurations based on Cramer-Rao lower bound analysis

Science.gov (United States)

Chen, Ling; Chen, Nanguang

2011-03-01

Optimization of source and detector (SD) arrangements in a diffuse optical tomography system is helpful for improving measurements' sensitivity to localized changes in imaging domain and enhancing the capacity of noise resistance. We introduced a rigorous and computationally efficient methodology and adapt it into the diffuse optics field to realize the optimizations of SD arrangements. Our method is based on Cramer-Rao lower bound analysis, which combines the diffusion-forward model and a noise model together. This method can be used to investigate the performance of the SD arrangements through quantitative estimations of lower bounds of the standard variances of the reconstructed perturbation depths and values. More importantly, it provides direct estimations of parameters without solving the inverse problem. Simulations are conducted in the reflection geometry to validate the effectiveness of the method on selections of the optimized SD sets, with a fixed number of sources and detectors, from an SD group on a planar probe surface. The impacts of different noise levels and target perturbation depths are considered in the simulations. It is demonstrated that the SD sets selected by this method afford better reconstructed images. This methodology can be adapted to other probe surfaces and other imaging geometries.

The Real-Valued Sparse Direction of Arrival (DOA Estimation Based on the Khatri-Rao Product

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Tao Chen

2016-05-01

Full Text Available There is a problem that complex operation which leads to a heavy calculation burden is required when the direction of arrival (DOA of a sparse signal is estimated by using the array covariance matrix. The solution of the multiple measurement vectors (MMV model is difficult. In this paper, a real-valued sparse DOA estimation algorithm based on the Khatri-Rao (KR product called the L1-RVSKR is proposed. The proposed algorithm is based on the sparse representation of the array covariance matrix. The array covariance matrix is transformed to a real-valued matrix via a unitary transformation so that a real-valued sparse model is achieved. The real-valued sparse model is vectorized for transforming to a single measurement vector (SMV model, and a new virtual overcomplete dictionary is constructed according to the KR product’s property. Finally, the sparse DOA estimation is solved by utilizing the idea of a sparse representation of array covariance vectors (SRACV. The simulation results demonstrate the superior performance and the low computational complexity of the proposed algorithm.

Faktor-faktor yang berhubungan dengan Pengolahan Sampah Organik Rumah Tangga menjadi Kompos di Jorong IX Pancahan Kecamatan Rao Kebupaten Pasaman Tahun 2013

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Nurdin ,

2015-07-01

Full Text Available Dari 10 responden yang di wawancarai oleh peneliti 6 responden mengaku mengetahui cara pembuatan kompos dan 4 di antaranya tidak mengetahui bagaimana cala pembuatan kompos. Dari hasil observasi yang peneliti lakukan responden membuang sampah rumah tangganya ke belakang rumah. Penelitian ini berlujuan untuk mengetahui Faktor-Faktor yang berhubungan dengan Pengolahan Sampah Organik Rumah Tangga Menjadi Kompos Di Jorong trX Pancahan Kecamatan Rao Kabupaten Pasaman Tahun 2013.Penelitian ini bersifat Deskriptif Analitik dengan pendekatan Cross secsional. Dan analisis data dilakukan dengan analisis univariat dan analisis bivariat dengan uji Chi Square. Populasi dalam penelitian ini adalah 330 kepala keluarga dengan jurnlah sampel 75 kepala keluarga yang ada di Jorong IX Pancahan Kecamatan Rao Kabupaten Pasatnan. Data diperoleh dengan cara wawancara dengan menggunakan kuesioner. Dimana variabel dependen adalah Pengolahan sampah organik rumah tangga menjadi kompos. sedangkan paria variabel independennya adalah pengetahuan, kebutuhan, dan kemampuan.Berdasarkan hasil penelitian terdapat 47 (6 I,8% responden mempunyai pengetahuan rendah dengan p=0,03 dan OR=0,308. Responden yang tidak membutuhkan kompos yaitu 44 (57,9% responden dengan p=0,05 dan OR=2,826. Responden yang mampu mengolah sarnpah organik rumah tangga 52 (68,4% responden dengan p=0,10 dan OR=2,623.Dapat disimpulkan bahwa sebagian besar masyarakat di Jorong IX Pancahan memiliki pengetahuan yang rendah" Pengetahuan dan kebutuhan berhubungan dengan pengolahan sampah organik rumah tangga menjadi kompos, sedangkan kemampuan tidak memiliki hubungan yang signifikan. Diperlukan upaya meningkatkan pengetahuan pengolahan sampah organik rumah tangga menjadi kompos dan memberikan pemahaman kepada mayarakat tentang kebutuhan dan manfaat kompos.Kata Kunci: Pengetahuan, kebutuhan, kemampuan, Sampah rumah tangga

Analysis of sensor impulse response effects on Cramèr–Rao lower bounds for signal parameter estimators

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Ephraim S. Gower

2014-12-01

Full Text Available In this study, a generic analysis of sensor impulse response effects on linearly filtered channel noise is presented to illustrate the resulting variations to the Cramèr–Rao lower bounds (CRLBs of signal parameter estimators in signal processing and communication applications. The authors start by deriving the density function of a filtered signal, which is shown to be a mixture density, and hence the exact expressions for the mean and variance. Simulation results are used to confirm the derivations, which are then used to investigate the effects of impulse response length and variance, as well as channel noise length and variance effects on the resulting CRLBs. Results indicate that for non-zero-mean channel noise and impulse responses, the resulting mean of filtered noise can be relatively large causing adverse deviations to parameter estimations. The filtered noise variance is shown to be proportional to the impulse response energy, where for long duration of signal capture the CRLB is significantly increased.

Frequency Diverse Array Radar Cramér-Rao Lower Bounds for Estimating Direction, Range, and Velocity

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Yongbing Wang

2014-01-01

Full Text Available Different from phased-array radar, frequency diverse array (FDA radar offers range-dependent beampattern and thus provides new application potentials. But there is a fundamental question: what estimation performance can achieve for an FDA radar? In this paper, we derive FDA radar Cramér-Rao lower bounds (CRLBs for estimating direction, range (time delay, and velocity (Doppler shift. Two different data models including pre- and postmatched filtering are investigated separately. As the FDA radar has range-angle coupling, we use a simple transmit subaperturing strategy which divides the whole array into two subarrays, each uses a distinct frequency increment. Assuming temporally white Gaussian noise and linear frequency modulated transmit signal, extensive simulation examples are performed. When compared to conventional phased-array radar, FDA can yield better CRLBs for estimating the direction, range, and velocity. Moreover, the impacts of the element number and frequency increment are also analyzed. Simulation results show that the CRLBs decrease with the increase of the elements number and frequency increment.

Three-Dimensional Target Localization and Cramér-Rao Bound for Two-Dimensional OFDM-MIMO Radar

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Xingxing Li

2017-01-01

Full Text Available Target localization using a frequency diversity multiple-input multiple-output (MIMO system is one of the hottest research directions in the radar society. In this paper, three-dimensional (3D target localization is considered for two-dimensional MIMO radar with orthogonal frequency division multiplexing linear frequency modulated (OFDM-LFM waveforms. To realize joint estimation for range and angle in azimuth and elevation, the range-angle-dependent beam pattern with high range resolution is produced by the OFDM-LFM waveform. Then, the 3D target localization proposal is presented and the corresponding closed-form expressions of Cramér-Rao bound (CRB are derived. Furthermore, for mitigating the coupling of angle and range and further improving the estimation precision, a CRB optimization method is proposed. Different from the existing methods of FDA-based radar, the proposed method can provide higher range estimation because of multiple transmitted frequency bands. Numerical simulation results are provided to demonstrate the effectiveness of the proposed approach and its improved performance of target localization.

Gibbs Sampler-Based λ-Dynamics and Rao-Blackwell Estimator for Alchemical Free Energy Calculation.

Science.gov (United States)

Ding, Xinqiang; Vilseck, Jonah Z; Hayes, Ryan L; Brooks, Charles L

2017-06-13

λ-dynamics is a generalized ensemble method for alchemical free energy calculations. In traditional λ-dynamics, the alchemical switch variable λ is treated as a continuous variable ranging from 0 to 1 and an empirical estimator is utilized to approximate the free energy. In the present article, we describe an alternative formulation of λ-dynamics that utilizes the Gibbs sampler framework, which we call Gibbs sampler-based λ-dynamics (GSLD). GSLD, like traditional λ-dynamics, can be readily extended to calculate free energy differences between multiple ligands in one simulation. We also introduce a new free energy estimator, the Rao-Blackwell estimator (RBE), for use in conjunction with GSLD. Compared with the current empirical estimator, the advantage of RBE is that RBE is an unbiased estimator and its variance is usually smaller than the current empirical estimator. We also show that the multistate Bennett acceptance ratio equation or the unbinned weighted histogram analysis method equation can be derived using the RBE. We illustrate the use and performance of this new free energy computational framework by application to a simple harmonic system as well as relevant calculations of small molecule relative free energies of solvation and binding to a protein receptor. Our findings demonstrate consistent and improved performance compared with conventional alchemical free energy methods.

Cognitive impairment in neuromyelitis optica spectrum disorders: A comparison of the Wechsler Adult Intelligence Scale-III and the Wechsler Memory Scale Revised with the Rao Brief Repeatable Neuropsychological Battery

OpenAIRE

Fujimori, Juichi; Nakashima, Ichiro; Baba, Toru; Meguro, Yuko; Ogawa, Ryo; Fujihara, Kazuo

2017-01-01

Background: Approximately 55% of patients with neuromyelitis optica spectrum disorder (NMOSD) show cognitive impairment as evaluated using the Rao Brief Repeatable Neuropsychological Battery (BRBN), but this frequency appears to be higher than the frequency of specific brain lesions in NMOSD. Objective: We studied whether cognitive impairment could be observed in NMOSD patients with no or minor non-specific brain lesions. Methods: We evaluated cognitive function in 12 NMOSD and 14 MS patients...

Imagen corporal, IMC, afrontamiento, depresión y riesgo de TCA en jóvenes universitarios

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Lina-María Hernández-Cortés

2013-10-01

Full Text Available El presente estudio descriptivo correlacional pretendió determinar la relación entre estilo de afrontamiento, historia psiquiátrica familiar, salud percibida, IMC, género, percepción de la figura y depresión y el riesgo de padecer un trastorno de conducta alimentaria. Participaron 417 estudiantes universitarios que se seleccionaron de manera no aleatorizada estratificada con grupos de conveniencia. Para obtener los datos se utilizó la Ficha de Registro de Información General, la Escala Abreviada de las actitudes alimentarias EAT -26-M, el Cuestionario de Formas de Afrontamiento, el Inventario de Depresión de Beck, la Prueba de Optimismo Disposicional y el Registro de Percepción de la Figura. El análisis de datos se llevo a cabo mediante el uso de ecuaciones estructurales. Se concluyó que la interacción de las variables antecedentes psicológicos familiares, género, deseo de disminución del peso, satisfacción con la imagen corporal, estilo de afrontamiento evitativo y depresión en conjunto predicen el riesgo de padecer un TCA, se discuten los hallazgos y se evidencian las limitaciones del presente estudio.

Perturbed soliton excitations of Rao-dust Alfvén waves in magnetized dusty plasmas

Energy Technology Data Exchange (ETDEWEB)

Kavitha, L., E-mail: louiskavitha@yahoo.co.in [Department of Physics, School of Basic and Applied Sciences, Central University of Tamil Nadu, Thiruvarur 610 101 (India); The Abdus Salam International Centre for Theoretical Physics, Trieste (Italy); Lavanya, C.; Senthil Kumar, V. [Department of Physics, Periyar University, Salem, Tamil Nadu 636 011 (India); Gopi, D. [Department of Chemistry, Periyar University, Salem 636 011 (India); Center for Nanoscience and Nanotechnology, Periyar University, Salem, Tamil Nadu 636 011 (India); Pasqua, A. [Department of Physics, University of Trieste, Trieste (Italy)

2016-04-15

We investigate the propagation dynamics of the perturbed soliton excitations in a three component fully ionized dusty magnetoplasma consisting of electrons, ions, and heavy charged dust particulates. We derive the governing equation of motion for the two dimensional Rao-dust magnetohydrodynamic (R-D-MHD) wave by employing the inertialess electron equation of motion, inertial ion equation of motion, the continuity equations in a plasma with immobile charged dust grains, together with the Maxwell's equations, by assuming quasi neutrality and neglecting the displacement current in Ampere's law. Furthermore, we assume the massive dust particles are practically immobile since we are interested in timescales much shorter than the dusty plasma period, thereby neglecting any damping of the modes due to the grain charge fluctuations. We invoke the reductive perturbation method to represent the governing dynamics by a perturbed cubic nonlinear Schrödinger (pCNLS) equation. We solve the pCNLS, along the lines of Kodama-Ablowitz multiple scale nonlinear perturbation technique and explored the R-D-MHD waves as solitary wave excitations in a magnetized dusty plasma. Since Alfvén waves play an important role in energy transport in driving field-aligned currents, particle acceleration and heating, solar flares, and the solar wind, this representation of R-D-MHD waves as soliton excitations may have extensive applications to study the lower part of the earth's ionosphere.

COSMIC MICROWAVE BACKGROUND LIKELIHOOD APPROXIMATION BY A GAUSSIANIZED BLACKWELL-RAO ESTIMATOR

International Nuclear Information System (INIS)

Rudjord, Oe.; Groeneboom, N. E.; Eriksen, H. K.; Huey, Greg; Gorski, K. M.; Jewell, J. B.

2009-01-01

We introduce a new cosmic microwave background (CMB) temperature likelihood approximation called the Gaussianized Blackwell-Rao estimator. This estimator is derived by transforming the observed marginal power spectrum distributions obtained by the CMB Gibbs sampler into standard univariate Gaussians, and then approximating their joint transformed distribution by a multivariate Gaussian. The method is exact for full-sky coverage and uniform noise and an excellent approximation for sky cuts and scanning patterns relevant for modern satellite experiments such as the Wilkinson Microwave Anisotropy Probe (WMAP) and Planck. The result is a stable, accurate, and computationally very efficient CMB temperature likelihood representation that allows the user to exploit the unique error propagation capabilities of the Gibbs sampler to high ls. A single evaluation of this estimator between l = 2 and 200 takes ∼0.2 CPU milliseconds, while for comparison, a singe pixel space likelihood evaluation between l = 2 and 30 for a map with ∼2500 pixels requires ∼20 s. We apply this tool to the five-year WMAP temperature data, and re-estimate the angular temperature power spectrum, C l , and likelihood, L(C l ), for l ≤ 200, and derive new cosmological parameters for the standard six-parameter ΛCDM model. Our spectrum is in excellent agreement with the official WMAP spectrum, but we find slight differences in the derived cosmological parameters. Most importantly, the spectral index of scalar perturbations is n s = 0.973 ± 0.014, 1.9σ away from unity and 0.6σ higher than the official WMAP result, n s = 0.965 ± 0.014. This suggests that an exact likelihood treatment is required to higher ls than previously believed, reinforcing and extending our conclusions from the three-year WMAP analysis. In that case, we found that the suboptimal likelihood approximation adopted between l = 12 and 30 by the WMAP team biased n s low by 0.4σ, while here we find that the same approximation

The stochastic Cramér-Rao bound for source localization and medium tomography using vector sensors.

Science.gov (United States)

Baggeroer, Arthur B

2017-05-01

A direct version for the stochastic Cramér-Rao bound (CRB) for parameters of Gaussian signals with additive Gaussian noise is introduced. The formulation applies to passive and active radars/sonars/seismics/structures with vector observations from multiple sources. These sensors include pressure, vector velocity, and/or acceleration sensors for ocean and structural acoustics, seismometers, polarized receivers for electromagnetics, and vector current meters for oceanography. The observations may contain partially coherent signals such as multipath. The parameters represent (i) signal localization or (ii) tomographic ones. As such, their embedding is very general using a Green's function vector and is not limited to direction of arrival problems. This formulation leads to simplified expressions for the stochastic CRB using just three quadratic forms involving just the Green's function and its derivatives with the inverse of the noise matrix for the norm. The number of the parameters sets the dimensions of these quadratic forms, so performance studies over the parameter space can be done with much smaller matrices as the noise covariance is inverted just once. The formulas are applied to vector sensors in jamming with both analytical and numerical results. The results are also compared to often cited papers on the CRB.

Cognitive impairment in neuromyelitis optica spectrum disorders: A comparison of the Wechsler Adult Intelligence Scale-III and the Wechsler Memory Scale Revised with the Rao Brief Repeatable Neuropsychological Battery

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Juichi Fujimori

2017-12-01

Full Text Available Background: Approximately 55% of patients with neuromyelitis optica spectrum disorder (NMOSD show cognitive impairment as evaluated using the Rao Brief Repeatable Neuropsychological Battery (BRBN, but this frequency appears to be higher than the frequency of specific brain lesions in NMOSD. Objective: We studied whether cognitive impairment could be observed in NMOSD patients with no or minor non-specific brain lesions. Methods: We evaluated cognitive function in 12 NMOSD and 14 MS patients using the Wechsler Adult Intelligence Scale-III (WAIS-III, the Wechsler Memory Scale-Revised (WMS-R, and the BRBN. We judged as cognitively impaired patients whose scores were below the average by 2 standard deviations or greater in 2 or more cognitive domains. Results: Cognitive impairment was observed in 5 MS patients (35.7% and in the only NMOSD patient (8.3% with symptomatic brain lesions, but not in the other NMOSD patients who had no or minor non-specific brain lesions. Meanwhile, 5 NMOSD (41.7% and 4 MS (28.6% patients who had normal cognition according to the WAIS-III and WMS-R were assessed as cognitively impaired by the BRBN (which is not standardized for age. Conclusions: Cognitive function in NMOSD patients with no or mild non-specific brain lesions was preserved according to the WAIS-III and WMS-R. Keywords: Neuromyelitis Optica, Cognitive impairment, Wechsler Adult Intelligence Scale-III, Wechsler Memory Scale-Revised, Rao Brief Repeatable Neuropsychological Battery, Multiple sclerosis

Seguimento de 9 anos da bioprótese valvular cardíaca de pericárdio bovino IMC-Biomédica: estudo multicêntrico Nine year follow-up of the bovine pericardial prosthetic valve IMC-Biomedica: a multicenter study

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Alexandre V Brick

1987-12-01

Full Text Available De dezembro de 1977 a novembro de 1986, foi usado o bioenxerto valvular cardíaco de pericárdio bovino IMC-Biomédica na posição mitral, em 798 pacientes, com idade média de 42 anos. Os 722 pacientes sobreviventes foram observados por um período de até 9 anos, representando 27036 meses, ou 2253 anos. O estudo indicou um índice de sobrevida de 66% para os adultos e 69% para os jovens, sendo de 94% e 80% o índice de sobrevida para os adultos e jovens, respectivamente, com pós-operatório de 5 anos. A freqüência das complicações diante da amostra analisada foi: 0,4% de rotura do tecido; 0,4% de vazamento paravalvular; 2,7% de acidente vascular cerebral; 3,2% de endocardite infecciosa; 4,4% de calcificação. A curva atuarial de calcificação entre os anos de 1978 e 1982 (Grupo I mostrou 94% dos adultos e 12% dos jovens livres dessa complicação. Por outro lado, de 1982 a 1986 (Grupo II, esse índice subiu para 99,0% entre os adultos e 92,0% para os jovens. Deste modo, concluímos que a nossa opção pela bioprótese de pericárdio bovino foi apropriada, visto que 96% dos pacientes estiveram livres de complicações fatais relacionadas à bioprótese, o que significa que, em 9 anos, o potencial da bioprótese foi apenas de 4%.A mitral pericardial bioprosthetic valve IMC-Biomedica was implanted in a consecutive series of 798 patients with mean age of 52 years, from December 1977 to November 1978. The 722 patients who survived operation were observed during a period of 9 years (mean 27036 months or 2253 years. Actuarial studies indicated an expected survived rate at 9 years of 66% for adult patients and 68% for younger patients. The probability of complications were the following: rupture 0.4; perivalvar leak 0.4%; thromboembolysm 2.7%; endocarditis 3.2%; calcification 4.4%. The actuarial freedom from calcification between 1977 to 1982 (Group I was 94.0% to adults and 12.0% to younger patients. On the other hand, between 1982 to 1986

Assessment of cognition using the Rao's Brief Repeatable Battery of Neuropsychological Tests on a group of Brazilian patients with multiple sclerosis

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Joseph Bruno Bidin Brooks

2011-12-01

Full Text Available To assess the cognition of patients with multiple sclerosis (MS using the Rao's Brief Repeatable Battery of Neuropsychological Tests (BRB-N. METHOD: BRB-N was translated and adapted for control subjects. Subsequently, it was applied to a group of patients with relapsing-remitting (RR MS. RESULTS: The assessment on the healthy controls (n=47 showed that the correlation between tests on the same cognitive domain was high and that there was a five-factor solution that explained 90% of the total variance. Except for the Word List Generation subset of tests, the performance of patients with RRMS (n=39 was worse than that of the healthy controls. CONCLUSION: BRB-N is a relatively simple method to assess cognition of patients with MS in the daily clinic. It does not take long to apply and does not require special skills or equipment.

Effect of Co on Si and Fe-containing intermetallic compounds (IMCs) in Al–20Si–5Fe alloys

International Nuclear Information System (INIS)

Fatih Kilicaslan, M.; Yilmaz, Fikret; Hong, Soon-Jik; Uzun, Orhan

2012-01-01

The effects of cobalt addition on microstructure and mechanical properties of Al–20Si–5Fe–XCo (X=0, 1, 3, and 5) alloys were reported in this study. The alloys were produced by both conventional sand casting and melt-spinning at 20 m/s disk velocity. Microstructures of the samples were investigated using X-ray diffractometry (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Vickers micro-hardness tester was used for hardness measurements. Results showed that Co addition can alter morphology of Fe-bearing intermetallic compounds (IMCs) from long rod/needle-like structures to short rod-like ones, and lead to a more homogenous distribution in the microstructure. Addition of 5 wt% Co leads to a decrease in average size of the primary silicon phases in as-cast Al–Si alloys. In melt-spun alloys, with the addition of Co, the microstructure became finer and more homogenously distributed, while thickness of the featureless zone has seen great increase. The optimum Fe to Co ratio was found to be 1 for suppressing the undesirable effect of Fe-bearing acicular/needle-like intermetallic compounds.

Effect of Co on Si and Fe-containing intermetallic compounds (IMCs) in Al-20Si-5Fe alloys

Energy Technology Data Exchange (ETDEWEB)

Fatih Kilicaslan, M. [Department of Physics, Faculty of Art and Science, Kastamonu University, Kastamonu (Turkey); Yilmaz, Fikret [Department of Physics, Faculty of Art and Science, Gaziosmanpasa University, Tokat (Turkey); Hong, Soon-Jik, E-mail: hongsj@kongju.ac.kr [Division of Advanced Materials Engineering, Institute for Rare Metals, Kongju National University, Cheonan 331717 (Korea, Republic of); Uzun, Orhan, E-mail: orhan.uzun@gop.edu.tr [Department of Physics, Faculty of Art and Science, Gaziosmanpasa University, Tokat (Turkey)

2012-10-30

The effects of cobalt addition on microstructure and mechanical properties of Al-20Si-5Fe-XCo (X=0, 1, 3, and 5) alloys were reported in this study. The alloys were produced by both conventional sand casting and melt-spinning at 20 m/s disk velocity. Microstructures of the samples were investigated using X-ray diffractometry (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Vickers micro-hardness tester was used for hardness measurements. Results showed that Co addition can alter morphology of Fe-bearing intermetallic compounds (IMCs) from long rod/needle-like structures to short rod-like ones, and lead to a more homogenous distribution in the microstructure. Addition of 5 wt% Co leads to a decrease in average size of the primary silicon phases in as-cast Al-Si alloys. In melt-spun alloys, with the addition of Co, the microstructure became finer and more homogenously distributed, while thickness of the featureless zone has seen great increase. The optimum Fe to Co ratio was found to be 1 for suppressing the undesirable effect of Fe-bearing acicular/needle-like intermetallic compounds.

An internal reference model-based PRF temperature mapping method with Cramer-Rao lower bound noise performance analysis.

Science.gov (United States)

Li, Cheng; Pan, Xinyi; Ying, Kui; Zhang, Qiang; An, Jing; Weng, Dehe; Qin, Wen; Li, Kuncheng

2009-11-01

The conventional phase difference method for MR thermometry suffers from disturbances caused by the presence of lipid protons, motion-induced error, and field drift. A signal model is presented with multi-echo gradient echo (GRE) sequence using a fat signal as an internal reference to overcome these problems. The internal reference signal model is fit to the water and fat signals by the extended Prony algorithm and the Levenberg-Marquardt algorithm to estimate the chemical shifts between water and fat which contain temperature information. A noise analysis of the signal model was conducted using the Cramer-Rao lower bound to evaluate the noise performance of various algorithms, the effects of imaging parameters, and the influence of the water:fat signal ratio in a sample on the temperature estimate. Comparison of the calculated temperature map and thermocouple temperature measurements shows that the maximum temperature estimation error is 0.614 degrees C, with a standard deviation of 0.06 degrees C, confirming the feasibility of this model-based temperature mapping method. The influence of sample water:fat signal ratio on the accuracy of the temperature estimate is evaluated in a water-fat mixed phantom experiment with an optimal ratio of approximately 0.66:1. (c) 2009 Wiley-Liss, Inc.

Report by the International Space Station (ISS) Management and Cost Evaluation (IMCE) Task Force

Science.gov (United States)

Young, A. Thomas; Kellogg, Yvonne (Technical Monitor)

2001-01-01

The International Space Station (ISS) Management and Cost Evaluation Task Force (IMCE) was chartered to conduct an independent external review and assessment of the ISS cost, budget, and management. In addition, the Task Force was asked to provide recommendations that could provide maximum benefit to the U.S. taxpayers and the International Partners within the President's budget request. The Task Force has made the following principal findings: (1) The ISS Program's technical achievements to date, as represented by on-orbit capability, are extraordinary; (2) The Existing ISS Program Plan for executing the FY 02-06 budget is not credible; (3) The existing deficiencies in management structure, institutional culture, cost estimating, and program control must be acknowledged and corrected for the Program to move forward in a credible fashion; (4) Additional budget flexibility, from within the Office of Space Flight (OSF) must be provided for a credible core complete program; (5) The research support program is proceeding assuming the budget that was in place before the FY02 budget runout reduction of $1B; (6) There are opportunities to maximize research on the core station program with modest cost impact; (7) The U.S. Core Complete configuration (three person crew) as an end-state will not achieve the unique research potential of the ISS; (8) The cost estimates for the U.S.-funded enhancement options (e.g., permanent seven person crew) are not sufficiently developed to assess credibility. After these findings, the Task Force has formulated several primary recommendations which are published here and include: (1) Major changes must be made in how the ISS program is managed; (2) Additional cost reductions are required within the baseline program; (3) Additional funds must be identified and applied from the Human Space Flight budget; (4) A clearly defined program with a credible end-state, agreed to by all stakeholders, must be developed and implemented.

A comparison of likelihood ratio tests and Rao's score test for three separable covariance matrix structures.

Science.gov (United States)

Filipiak, Katarzyna; Klein, Daniel; Roy, Anuradha

2017-01-01

The problem of testing the separability of a covariance matrix against an unstructured variance-covariance matrix is studied in the context of multivariate repeated measures data using Rao's score test (RST). The RST statistic is developed with the first component of the separable structure as a first-order autoregressive (AR(1)) correlation matrix or an unstructured (UN) covariance matrix under the assumption of multivariate normality. It is shown that the distribution of the RST statistic under the null hypothesis of any separability does not depend on the true values of the mean or the unstructured components of the separable structure. A significant advantage of the RST is that it can be performed for small samples, even smaller than the dimension of the data, where the likelihood ratio test (LRT) cannot be used, and it outperforms the standard LRT in a number of contexts. Monte Carlo simulations are then used to study the comparative behavior of the null distribution of the RST statistic, as well as that of the LRT statistic, in terms of sample size considerations, and for the estimation of the empirical percentiles. Our findings are compared with existing results where the first component of the separable structure is a compound symmetry (CS) correlation matrix. It is also shown by simulations that the empirical null distribution of the RST statistic converges faster than the empirical null distribution of the LRT statistic to the limiting χ 2 distribution. The tests are implemented on a real dataset from medical studies. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Sugar-sweetened beverages consumption and BMI in Mexican adolescents: Mexican National Health and Nutrition Survey 2006 Consumo de bebidas azucaradas y su relación con el IMC en adolescentes mexicanos: Encuesta Nacional de Salud y Nutrición 2006

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Alejandra Jiménez-Aguilar

2009-01-01

Full Text Available OBJECTIVE: To evaluate the association between the consumption of sugar-sweetened beverages (SSBs and body mass index (BMI in Mexican adolescents. MATERIAL AND METHODS: We analyzed the data of 10 689 adolescents (ages 10 to 19 years old who participated in the Mexican National Health and Nutrition Survey 2006 (ENSANUT 2006. Consumption of SSBs (i.e. sodas, fruit beverages and sugar beverages was evaluated by means of a semi-quantitative food frequency questionnaire. BMI was calculated (kg/m². RESULTS: Mean age was 13.8 ± 2.7 years. Fifty percent were females. Mean BMI was 21.7 ± 4.5. Thirty percent of adolescents were overweight or obese. Ninety percent of adolescents consumed at least one SSB during the 7 days before the interview. The median consumption of SSBs was 0.89 portion per day. Multiple-linear regression analysis showed that for each portion of sodas consumed, a 0.17-point increase in BMI was observed in boys after adjusting for confounders (95% CI; 0.02-0.32, p 0.03. Positive interactions of SSB consumption with age and time watching TV were observed in boys. CONCLUSIONS: Consumption of sodas was positively associated with BMI in Mexican boys.OBJETIVO: Examinar la asociación entre el consumo de bebidas refrescantes azucaradas (BRA y el índice de masa corporal (IMC en adolescentes mexicanos. MATERIAL Y MÉTODOS: Se analizaron datos de 10 689 adolescentes (10 a 19 años de edad de la Encuesta Nacional de Salud y Nutrición 2006 (ENSANUT 2006. El consumo de bebidas refrescantes azucaradas (BRA: refrescos, bebidas de fruta y bebidas endulzadas se evaluó con un cuestionario semicuantitativo de frecuencia de consumo de alimentos. Se calculó el índice de masa corporal (kg/m². RESULTADOS: La media de edad fue de 13.8 ± 2.7 años. El 50.4% fueron mujeres. La media de IMC fue de 21.7 ± 4.5. Un 30% de los adolescentes presentó sobrepeso u obesidad. El 90% de los adolescentes consumieron al menos una BRA en los 7 días previos a la

Fisher information and Cramér-Rao lower bound for experimental design in parallel imaging.

Science.gov (United States)

Bouhrara, Mustapha; Spencer, Richard G

2018-06-01

The Cramér-Rao lower bound (CRLB) is widely used in the design of magnetic resonance (MR) experiments for parameter estimation. Previous work has considered only Gaussian or Rician noise distributions in this calculation. However, the noise distribution for multi-coil acquisitions, such as in parallel imaging, obeys the noncentral χ-distribution under many circumstances. The purpose of this paper is to present the CRLB calculation for parameter estimation from multi-coil acquisitions. We perform explicit calculations of Fisher matrix elements and the associated CRLB for noise distributions following the noncentral χ-distribution. The special case of diffusion kurtosis is examined as an important example. For comparison with analytic results, Monte Carlo (MC) simulations were conducted to evaluate experimental minimum standard deviations (SDs) in the estimation of diffusion kurtosis model parameters. Results were obtained for a range of signal-to-noise ratios (SNRs), and for both the conventional case of Gaussian noise distribution and noncentral χ-distribution with different numbers of coils, m. At low-to-moderate SNR, the noncentral χ-distribution deviates substantially from the Gaussian distribution. Our results indicate that this departure is more pronounced for larger values of m. As expected, the minimum SDs (i.e., CRLB) in derived diffusion kurtosis model parameters assuming a noncentral χ-distribution provided a closer match to the MC simulations as compared to the Gaussian results. Estimates of minimum variance for parameter estimation and experimental design provided by the CRLB must account for the noncentral χ-distribution of noise in multi-coil acquisitions, especially in the low-to-moderate SNR regime. Magn Reson Med 79:3249-3255, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

CORRELAÇÃO ENTRE O IMC E AS CAPACIDADES MOTORAS CONDICIONAIS EM JOVENS PRATICANTES DE MODALIDADES DESPORTIVAS EXTRA-CURRICULARES

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C. Alves

2015-04-01

Full Text Available As capacidades motoras são “a base para a capacidade de aprendizagem sensorial e motora”, responsáveis pela execução de uma ação, desde a mais simples à mais complexa (andar, correr, etc. (Moraes, 2003. Estas capacidades são condicionadas por fatores genéticos, contudo, desenvolvem-se através do treino, potenciando um elevado desempenho motor (Moraes, 2003. É, por isso, importante avaliar as capacidades motoras dos jovens, adequando por esta via, as experiências motoras a cada criança/grupo de crianças e/ou jovens (Neto, Marcarenhas, Nunes, Lepre & Campos, 2004. As relações entre a prática de atividade física e obesidade configuram-se como objeto de estudo prioritário e as evidências na literatura apontam para a existência de associação entre o excesso de peso na adolescência e alterações da sua saúde na idade adulta, dado o excesso de gordura corporal, além de ser fator de risco para diversas doenças, prejudica o desempenho físico. Objetivo: Analisar a associação entre o IMC e as Capacidades Motoras Condicionais em jovens praticantes de modalidades desportivas extra-curriculares.

Predicting minimum uncertainties in the inversion of ocean color geophysical parameters based on Cramer-Rao bounds.

Science.gov (United States)

Jay, Sylvain; Guillaume, Mireille; Chami, Malik; Minghelli, Audrey; Deville, Yannick; Lafrance, Bruno; Serfaty, Véronique

2018-01-22

We present an analytical approach based on Cramer-Rao Bounds (CRBs) to investigate the uncertainties in estimated ocean color parameters resulting from the propagation of uncertainties in the bio-optical reflectance modeling through the inversion process. Based on given bio-optical and noise probabilistic models, CRBs can be computed efficiently for any set of ocean color parameters and any sensor configuration, directly providing the minimum estimation variance that can be possibly attained by any unbiased estimator of any targeted parameter. Here, CRBs are explicitly developed using (1) two water reflectance models corresponding to deep and shallow waters, resp., and (2) four probabilistic models describing the environmental noises observed within four Sentinel-2 MSI, HICO, Sentinel-3 OLCI and MODIS images, resp. For both deep and shallow waters, CRBs are shown to be consistent with the experimental estimation variances obtained using two published remote-sensing methods, while not requiring one to perform any inversion. CRBs are also used to investigate to what extent perfect a priori knowledge on one or several geophysical parameters can improve the estimation of remaining unknown parameters. For example, using pre-existing knowledge of bathymetry (e.g., derived from LiDAR) within the inversion is shown to greatly improve the retrieval of bottom cover for shallow waters. Finally, CRBs are shown to provide valuable information on the best estimation performances that may be achieved with the MSI, HICO, OLCI and MODIS configurations for a variety of oceanic, coastal and inland waters. CRBs are thus demonstrated to be an informative and efficient tool to characterize minimum uncertainties in inverted ocean color geophysical parameters.

Cramer-Rao Lower Bound Evaluation for Linear Frequency Modulation Based Active Radar Networks Operating in a Rice Fading Environment.

Science.gov (United States)

Shi, Chenguang; Salous, Sana; Wang, Fei; Zhou, Jianjiang

2016-12-06

This paper investigates the joint target parameter (delay and Doppler) estimation performance of linear frequency modulation (LFM)-based radar networks in a Rice fading environment. The active radar networks are composed of multiple radar transmitters and multichannel receivers placed on moving platforms. First, the log-likelihood function of the received signal for a Rician target is derived, where the received signal scattered off the target comprises of dominant scatterer (DS) component and weak isotropic scatterers (WIS) components. Then, the analytically closed-form expressions of the Cramer-Rao lower bounds (CRLBs) on the Cartesian coordinates of target position and velocity are calculated, which can be adopted as a performance metric to access the target parameter estimation accuracy for LFM-based radar network systems in a Rice fading environment. It is found that the cumulative Fisher information matrix (FIM) is a linear combination of both DS component and WIS components, and it also demonstrates that the joint CRLB is a function of signal-to-noise ratio (SNR), target's radar cross section (RCS) and transmitted waveform parameters, as well as the relative geometry between the target and the radar network architectures. Finally, numerical results are provided to indicate that the joint target parameter estimation performance of active radar networks can be significantly improved with the exploitation of DS component.

Cramer-Rao Lower Bound Evaluation for Linear Frequency Modulation Based Active Radar Networks Operating in a Rice Fading Environment

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Chenguang Shi

2016-12-01

Full Text Available This paper investigates the joint target parameter (delay and Doppler estimation performance of linear frequency modulation (LFM-based radar networks in a Rice fading environment. The active radar networks are composed of multiple radar transmitters and multichannel receivers placed on moving platforms. First, the log-likelihood function of the received signal for a Rician target is derived, where the received signal scattered off the target comprises of dominant scatterer (DS component and weak isotropic scatterers (WIS components. Then, the analytically closed-form expressions of the Cramer-Rao lower bounds (CRLBs on the Cartesian coordinates of target position and velocity are calculated, which can be adopted as a performance metric to access the target parameter estimation accuracy for LFM-based radar network systems in a Rice fading environment. It is found that the cumulative Fisher information matrix (FIM is a linear combination of both DS component and WIS components, and it also demonstrates that the joint CRLB is a function of signal-to-noise ratio (SNR, target’s radar cross section (RCS and transmitted waveform parameters, as well as the relative geometry between the target and the radar network architectures. Finally, numerical results are provided to indicate that the joint target parameter estimation performance of active radar networks can be significantly improved with the exploitation of DS component.

Application of a partitioning procedure based on Rao quadratic entropy index to characterize the temporal evolution of in situ varietal and genetic diversity of bread wheat in France over the period 1981-2006.

Science.gov (United States)

Perronne, Rémi; Goldringer, Isabelle

2018-04-01

We present and highlight a partitioning procedure based on the Rao quadratic entropy index to assess temporal in situ inter-annual varietal and genetic changes of crop diversity. For decades, Western-European agroecosystems have undergone profound changes, among which a reduction of crop genetic diversity. These changes have been highlighted in numerous studies, but no unified partitioning procedure has been proposed to compute the inter-annual variability in both varietal and genetic diversity. To fill this gap, we tested, adjusted and applied a partitioning procedure based on the Rao quadratic entropy index that made possible to describe the different components of crop diversity as well as to account for the relative acreages of varieties. To emphasize the relevance of this procedure, we relied on a case study focusing on the temporal evolution of bread wheat diversity in France over the period 1981-2006 at both national and district scales. At the national scale, we highlighted a decrease of the weighted genetic replacement indicating that varieties sown in the most recent years were more genetically similar than older ones. At the district scale, we highlighted sudden changes in weighted genetic replacement in some agricultural regions that could be due to fast shifts of successive leading varieties over time. Other regions presented a relatively continuous increase of genetic similarity over time, potentially due to the coexistence of a larger number of co-leading varieties that got closer genetically. Based on the partitioning procedure, we argue that a tendency of in situ genetic homogenization could be compared to some of its potential causes, such as a decrease in the speed of replacement or an increase in between-variety genetic similarity over time.

Neutron capture therapy of epidermal growth factor (+) gliomas using boronated cetuximab (IMC-C225) as a delivery agent

Energy Technology Data Exchange (ETDEWEB)

Barth, Rolf F. E-mail: barth.1@osu.edu; Wu Gong; Yang Weilian; Binns, Peter J.; Riley, Kent J.; Patel, Hemant; Coderre, Jeffrey A.; Tjarks, Werner; Bandyopadhyaya, A.K.; Thirumamagal, B.T.S.; Ciesielski, Michael J.; Fenstermaker, Robert A

2004-11-01

Cetuximab (IMC-C225) is a monoclonal antibody directed against both the wild-type and mutant vIII isoform of the epidermal growth factor receptor (EGFR). The purpose of the present study was to evaluate the monoclonal antibody (MoAb), cetuximab, as a boron delivery agent for neutron capture therapy (NCT) of brain tumors. Twenty-four hours following intratumoral (i.t.) administration of boronated cetuximab (C225-G5-B{sub 1100}), the mean boron concentration in rats bearing either F98{sub EGFR} or F98{sub WT} gliomas were 92.3{+-}23.3 {mu}g/g and 36.5{+-}18.8 {mu}g/g, respectively. In contrast, the uptake of boronated dendrimer (G5-B{sub 1000}) was 6.7{+-}3.6 {mu}g/g. Based on its favorable in vivo uptake, C225-G5-B{sub 1100} was evaluated as a delivery agent for BNCT in F98{sub EGFR} glioma bearing rats. The mean survival time (MST) of rats that received C225-G5-B{sub 1100}, administered by convection enhanced delivery (CED), was 45{+-}3 d compared to 25{+-}3 d for untreated control animals. A further enhancement in MST to >59 d was obtained by administering C225-G5-B{sub 1100} in combination with i.v. boronophenylalanine (BPA). These data are the first to demonstrate the efficacy of a boronated MoAb for BNCT of an intracerebral (i.c.) glioma and are paradigmatic for future studies using a combination of boronated MoAbs and low molecular weight delivery agents.

Differential Roles for Inner Membrane Complex Proteins across Toxoplasma gondii and Sarcocystis neurona Development.

Science.gov (United States)

Dubey, Rashmi; Harrison, Brooke; Dangoudoubiyam, Sriveny; Bandini, Giulia; Cheng, Katherine; Kosber, Aziz; Agop-Nersesian, Carolina; Howe, Daniel K; Samuelson, John; Ferguson, David J P; Gubbels, Marc-Jan

2017-01-01

The inner membrane complex (IMC) of apicomplexan parasites contains a network of intermediate filament-like proteins. The 14 alveolin domain-containing IMC proteins in Toxoplasma gondii fall into different groups defined by their distinct spatiotemporal dynamics during the internal budding process of tachyzoites. Here, we analyzed representatives of different IMC protein groups across all stages of the Toxoplasma life cycle and during Sarcocystis neurona asexual development. We found that across asexually dividing Toxoplasma stages, IMC7 is present exclusively in the mother's cytoskeleton, whereas IMC1 and IMC3 are both present in mother and daughter cytoskeletons (IMC3 is strongly enriched in daughter buds). In developing macro- and microgametocytes, IMC1 and -3 are absent, whereas IMC7 is lost in early microgametocytes but retained in macrogametocytes until late in their development. We found no roles for IMC proteins during meiosis and sporoblast formation. However, we observed that IMC1 and IMC3, but not IMC7, are present in sporozoites. Although the spatiotemporal pattern of IMC15 and IMC3 suggests orthologous functions in Sarcocystis , IMC7 may have functionally diverged in Sarcocystis merozoites. To functionally characterize IMC proteins, we knocked out IMC7, -12, -14, and -15 in Toxoplasma . IMC14 and -15 appear to be involved in switching between endodyogeny and endopolygeny. In addition, IMC7, -12, and -14, which are all recruited to the cytoskeleton outside cytokinesis, are critical for the structural integrity of extracellular tachyzoites. Altogether, stage- and development-specific roles for IMC proteins can be discerned, suggesting different niches for each IMC protein across the entire life cycle. IMPORTANCE The inner membrane complex (IMC) is a defining feature of apicomplexan parasites key to both their motility and unique cell division. To provide further insights into the IMC, we analyzed the dynamics and functions of representative alveolin

Synthetic Vision Systems in GA Cockpit-Evaluation of Basic Maneuvers Performed by Low Time GA Pilots During Transition from VMC to IMC

Science.gov (United States)

Takallu, M. A.; Wong, D. T.; Uenking, M. D.

2002-01-01

An experimental investigation was conducted to study the effectiveness of modern flight displays in general aviation cockpits for mitigating Low Visibility Loss of Control and the Controlled Flight Into Terrain accidents. A total of 18 General Aviation (GA) pilots with private pilot, single engine land rating, with no additional instrument training beyond private pilot license requirements, were recruited to evaluate three different display concepts in a fixed-based flight simulator at the NASA Langley Research Center's General Aviation Work Station. Evaluation pilots were asked to continue flight from Visual Meteorological Conditions (VMC) into Instrument Meteorological Conditions (IMC) while performing a series of 4 basic precision maneuvers. During the experiment, relevant pilot/vehicle performance variables, pilot control inputs and physiological data were recorded. Human factors questionnaires and interviews were administered after each scenario. Qualitative and quantitative data have been analyzed and the results are presented here. Pilot performance deviations from the established target values (errors) were computed and compared with the FAA Practical Test Standards. Results of the quantitative data indicate that evaluation pilots committed substantially fewer errors when using the Synthetic Vision Systems (SVS) displays than when they were using conventional instruments. Results of the qualitative data indicate that evaluation pilots perceived themselves to have a much higher level of situation awareness while using the SVS display concept.

Relação entre atividade física e desportiva, níveis de IMC, perceções de sucesso e rendimento escolar

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Fernando Bastos

2015-12-01

Full Text Available O excesso de peso é cada vez maior entre da população escolar jovem. Uma vez que não é evidente qual a atitude dos alunos com sobrepeso e obesidade face à participação em atividades físicas e sua relação com o desempenho escolar pretendemos identificar os factores de influência no contexto da EF escolar. Participaram neste estudo 490 alunos dos 3º ciclo e ensino secundário, divididos por sexo. Os valores de IMC foram ajustados para sexo e idade e criados três grupos: Magreza; peso normal; e excesso de peso. Os valores dos resultados escolares foram normalizadas para uma escala de 1 a 5 valores. A participação em atividades desportivas, regularidade de prática e percepção do sucesso escolar foi medida por questionário. Após análise exploratória dos dados foram realizados os testes do Qui-quadrado, ANOVA e correlação de Pearson. O eta quadrado parcial (η² foi reportado como medida da magnitude do efeito das diferenças verificadas nas ANOVAs. Foi considerado o valor de α de 0.05. Os resultados mostraram que alunos com excesso de peso e magreza reportaram menores níveis de atividade física em relação a alunos normoponderais (4.20±1.73, 4.06±1.77, 4.61±1.73; p=0.044; η²=0.01, resp.. A maior parte dos alunos definiu o seu sucesso escolar através da aprovação/transição de ano a par de boas classificações, tendo este grupo obtido níveis superiores de prática (4.57±1.71, p=0.03 Verificaram-se efeitos significativos da variável níveis de IMC nas classificações médias finais e na disciplina de EF, em que os alunos normoponderais obtiveram melhores classificações do que os alunos com excesso de peso. Além disso, verificaram-se correlações significativas entre as classificações de Português e Matemática (r=0.80; p<0.001, entre as classificações de EF e Português (r=0.36; p<0.001, e entre as classificações de EF e Matemática (r=0.42; p<0.001. Os alunos com sobrepeso apresentaram n

Revisiting the Cramér Rao Lower Bound for Elastography: Predicting the Performance of Axial, Lateral and Polar Strain Elastograms.

Science.gov (United States)

Verma, Prashant; Doyley, Marvin M

2017-09-01

We derived the Cramér Rao lower bound for 2-D estimators employed in quasi-static elastography. To illustrate the theory, we modeled the 2-D point spread function as a sinc-modulated sine pulse in the axial direction and as a sinc function in the lateral direction. We compared theoretical predictions of the variance incurred in displacements and strains when quasi-static elastography was performed under varying conditions (different scanning methods, different configuration of conventional linear array imaging and different-size kernels) with those measured from simulated or experimentally acquired data. We performed studies to illustrate the application of the derived expressions when performing vascular elastography with plane wave and compounded plane wave imaging. Standard deviations in lateral displacements were an order higher than those in axial. Additionally, the derived expressions predicted that peak performance should occur when 2% strain is applied, the same order of magnitude as observed in simulations (1%) and experiments (1%-2%). We assessed how different configurations of conventional linear array imaging (number of active reception and transmission elements) influenced the quality of axial and lateral strain elastograms. The theoretical expressions predicted that 2-D echo tracking should be performed with wide kernels, but the length of the kernels should be selected using knowledge of the magnitude of the applied strain: specifically, longer kernels for small strains (<5%) and shorter kernels for larger strains. Although the general trends of theoretical predictions and experimental observations were similar, biases incurred during beamforming and subsample displacement estimation produced noticeable differences. Copyright © 2017 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug-polymer mixtures

DEFF Research Database (Denmark)

Priemel, Petra A; Laitinen, Riikka; Barthold, Sarah

2013-01-01

stability than pure IMC whereas IMC Soluplus(®) mixtures did not. Water uptake was higher for mixtures containing Soluplus(®) than for amorphous IMC or IMC Eudragit(®) mixtures. However, the Tg of amorphous IMC was unaffected by the presence (and nature) of polymer. SEM revealed that Eudragit(®) particles...... through reduced IMC surface molecular mobility. Polymer particles may also mechanically hinder crystal growth outwards from the surface. This work highlights the importance of microparticulate surface coverage of amorphous drug particles on their stability....

Retinal artery occlusion and associated recurrent vascular risk with underlying etiologies.

Directory of Open Access Journals (Sweden)

Jeong-Ho Hong

Full Text Available RAO is caused by various etiologies and subsequent vascular events may be associated with underlying etiologies. Our aim is to investigate the etiologies of RAO, the occurrence of subsequent vascular events and their association in patients with RAO.We analyzed data from 151 consecutive patients presenting with acute non-arteritic RAO between 2003 and 2013 in a single tertiary-care hospital. The primary outcome was the occurrence of a vascular event defined as stroke, myocardial infarction, and vascular death within 365 days of the RAO onset. The Kaplan-Meier survival analysis and Cox proportional hazard model were used to estimate the hazard ratio of the vascular events.Large artery atherosclerosis (LAA was the etiology more frequently associated with of RAO (41.1%, 62/151. During the one year follow-up, ischemic stroke and vascular events occurred in 8.6% and 9.9% of patients, respectively. Ten vascular events occurred in RAO patients attributed to LAA and 4 occurred in undetermined etiology. RAO patients with LAA had a nearly four times higher risk of vascular events compared to those without LAA (hazard ratio 3.94, 95% confidence interval 1.21-12.81. More than a half of all events occurred within one month and over three fourths of ischemic strokes occurred ipsilateral to the RAO.After occurrence of RAO, there is a high risk of a subsequent vascular event, particularly ipsilateral stroke, within one month. LAA is an independent factor for the occurrence of a subsequent vascular event. Management for the prevention of secondary vascular events is necessary in patients with RAO especially with LAA. Large clinical trials are needed to confirm these findings.

Verdine and glaucony facies from surficial sediments of the eastern continental margin of India

Digital Repository Service at National Institute of Oceanography (India)

Rao, V.P.; Thamban, M.; Lamboy, M.

-trioctahedral Fe-rich 1:l clay mineral. Clay Miner., 23: 237-247. Murthy, K.S.R., 1989. Seismic stratigraphy of Ongole-Paradip continental shelf East coast of India. Indian J. Mar. Sci., 16: 47-58. Murthy, K.S.R., Rao, T.C.S., Subramanyam, AS., Rao, M... at the continent- ocean boundary: the verdine facies. Clay Miner. 25: 477-483. Rao, K.M. and Rao, T.C.S., 1994. Holocene sea levels of Visakhapatnam shelf, East Coast of India. J. Geol. Sot. India, 44: 685-689. Rao, V.P., 1991. Clay mineral distribution...

Radiological protection regulation during spent nuclear fuel and radioactive waste management in the western branch of the Federal State Unitary Enterprise 'SevRAO'.

Science.gov (United States)

Simakov, A V; Sneve, M K; Abramov, Yu V; Kochetkov, O A; Smith, G M; Tsovianov, A G; Romanov, V V

2008-12-01

The site of temporary storage of spent nuclear fuel and radioactive waste, situated at Andreeva Bay in Northwest Russia, was developed in the 1960s, and it has carried out receipt and storage of fresh and spent nuclear fuel, and solid and liquid radioactive waste generated during the operation of nuclear submarines and nuclear-powered icebreakers. The site is now operated as the western branch of the Federal State Unitary Enterprise, SevRAO. In the course of operation over several decades, the containment barriers in the Spent Nuclear Fuel and Radioactive Waste storage facilities partially lost their containment effectiveness, so workshop facilities and parts of the site became contaminated with radioactive substances. This paper describes work being undertaken to provide an updated regulatory basis for the protection of workers during especially hazardous remediation activities, necessary because of the unusual radiation conditions at the site. It describes the results of recent survey work carried out by the Burnasyan Federal Medical Biophysical Centre, within a programme of regulatory cooperation between the Norwegian Radiation Protection Authority and the Federal Medical-Biological Agency of Russia. The survey work and subsequent analyses have contributed to the development of special regulations setting out radiological protection requirements for operations planned at the site. Within these requirements, and taking account of a variety of other factors, a continuing need arises for the implementation of optimisation of remediation at Andreeva Bay.

Intima-media thickness evaluation by B-mode ultrasound: Correlation with blood pressure levels and cardiac structures

Directory of Open Access Journals (Sweden)

F.L. Plavnik

2000-01-01

Full Text Available The aim of this study was to analyze the thickness of the intima-media complex (IMC using a noninvasive method. The carotid and femoral common arteries were evaluated by noninvasive B-mode ultrasound in 63 normotensive and in 52 hypertensive subjects and the thickness of the IMC was tested for correlation with blood pressure, cardiac structures and several clinical and biological parameters. The IMC was thicker in hypertensive than in normotensive subjects (0.67 ± 0.13 and 0.62 ± 0.16 vs 0.54 ± 0.09 and 0.52 ± 0.11 mm, respectively, P<0.0001. In normotensive patients, the simple linear regression showed significant correlations between IMC and age, body mass index and 24-h systolic blood pressure for both the carotid and femoral arteries. In hypertensives the carotid IMC was correlated with age and 24-h systolic blood pressure while femoral IMC was correlated only with 24-h diastolic blood pressure. Forward stepwise regression showed that age, body mass index and 24-h systolic blood pressure influenced the carotid IMC relationship (r2 = 0.39 in normotensives. On the other hand, the femoral IMC relationship was influenced by 24-h systolic blood pressure and age (r2 = 0.40. In hypertensives, age and 24-h systolic blood pressure were the most important determinants of carotid IMC (r2 = 0.37, while femoral IMC was influenced only by 24-h diastolic blood pressure (r2 = 0.10. There was an association between carotid IMC and echocardiographic findings in normotensives, while in hypertensives only the left posterior wall and interventricular septum were associated with femoral IMC. We conclude that age and blood pressure influence the intima-media thickness, while echocardiographic changes are associated with the IMC.

Cooling crystallization of Indomethacin from different organic solvents

DEFF Research Database (Denmark)

Malwade, Chandrakant Ramkrishna; Qu, Haiyan

, 25, 35, and 45 °C. The solvents with varying polarities (ethanol, methanol, ethyl acetate, acetone, acetonitrile, and dichloromethane) were used for solubility measurement. Maximum solubility of IMC was observed in acetone, while acetonitrile showed the lowest solubility. Solid phase analysis...... of excess solute with XRPD and Raman spectroscopy confirmed formation of IMC solvate in acetone, methanol and dichloromethane at 15 °C. Based on solubility of IMC, the solvents ethanol, ethyl acetate, acetone, and dichloromethane were selected for crystallization experiments. Nucleation kinetics of IMC...... in selected solvents was investigated through the measurement of induction time at 5 °C and 15 °C. Longer induction times were observed for IMC in ethanol at both temperatures compared to the one in acetone. Metastable α form of IMC was obtained from ethanol, while solvate of IMC was produced from acetone....

National Statistical Commission and Indian Official Statistics

Indian Academy of Sciences (India)

Author Affiliations. T J Rao1. C. R. Rao Advanced Institute of Mathematics, Statistics and Computer Science (AIMSCS) University of Hyderabad Campus Central University Post Office, Prof. C. R. Rao Road Hyderabad 500 046, AP, India.

Rao, Prof. Sumathi

Indian Academy of Sciences (India)

Ethical Guidelines and Procedures document. Posted on 17 January 2017. A revised version of the document 'Scientific Values: Ethical Guidelines and Procedures' has been produced by the Academy's Panel on Scientific Values. For more details, see the Academy Committee on Scientific Values page.

Info (TR Rao)

Indian Academy of Sciences (India)

) measured in Scoville Units (SUs). Pure capsaicin: 16 M SU. Smoking Ed's Carolina reaper: 1.47 MSU. Tezpur mirchi: 0.855 MSU; 163 times the jalapeno pepper. Bhut Jolokia 1.6M; infinity chilli: 1.2M, Naga Viper: 1.4 M; Trinidad Moruga ...

Evaluation of the physicochemical and biopharmaceutical properties of fluoro-indomethacin.

Science.gov (United States)

Mori, Michela M; Airaksinen, Anu J; Hirvonen, Jouni T; Santos, Hélder A; Caramella, Carla M

2013-01-01

Drug nanocarriers have shown great potential in therapy and as diagnostic probes, e.g. in imaging of cancer and inflammation. Imaging can be applied to localize the carrier or the drug itself in the body and/or tissues. In this particular case it is important that drug molecules have the characteristics for possible detection, e.g. after modification with positron emission tomography compliant radioisotopes, without affecting their pharmacological behavior. In order to easily and efficiently follow the ADME profile of the drug after loaded into nanocarriers, the drug can be radiolabelled with, e.g. 18F-label, in order to assess its biodistribution after enteral and parenteral administration in rats. However, this is only possible if the derivative compound behaves similarly to the parent drug compound. In this study, indomethacin (a poorly water-soluble drug) was chosen as a model compound and aimed to evaluate the physicochemical and biopharmaceutical properties of an analog of indomethacin (IMC), fluoro-indomethacin (F-IMC). Although some of the physicochemical and biopharmaceutical properties of IMC are already known, in order to establish a feasible comparison between IMC and F-IMC, the behavior of the former was also investigated in the same conditions as for F-IMC. In this context, both IMC and F-IMC were thermally and morphologically studied. Furthermore, the following properties were also studied for both compounds: pKa and logP, solubility and dissolution profiles at physiological pH values, and toxicity at different concentrations in Caco-2 cells. Finally, the transport across Caco- 2 monolayers of the IMC and F-IMC at physiological pH range was also investigated. The results obtained showed similar values in pKalogP, solubility, dissolution, cytotoxicity, and permeability for both compounds. Thus, there might be strong evidence that both IMC and F-IMC should have a similar ADME behavior and profiles in vivo. The results provide fundamental tools and

Al/Cu Dissimilar Friction Stir Welding with Ni, Ti, and Zn Foil as the Interlayer for Flow Control, Enhancing Mechanical and Metallurgical Properties

Science.gov (United States)

Sahu, Prakash Kumar; Pal, Sukhomay; Pal, Surjya K.

2017-07-01

This research investigates the effects of Ni, Ti, and Zn foil as interlayer, inserted between the faying edges of Al and Cu plates, for controlled intermetallic compound (IMC) formation. The weld tensile strength with Ti and Zn as interlayer is superior to Al base metal strength. This is due to controlled flow of IMCs by diffused Ti interlayer and thin, continuous, and uniform IMC formation in the case of Zn interlayer. Improved flexural stress was observed with interlayer. Weld microhardness varied with different interlayers and purely depends on IMCs present at the indentation point, flow of IMCs, and interlayer hardness. Specimens with interlayer failed at the interface of the nugget and thermomechanical-affected zone (TMAZ) with complete and broken three-dimensional (3-D) grains, indicating transgranular fracture. Phase analysis revealed that Al/Cu IMCs are impeded by Ni and Ti interlayer. The minor binary and ternary IMC phases form adjacent to the interlayer due to diffusion of the material with Al/Cu. Line scan and elemental mapping indicate thin, continuous, and uniform IMCs with enhanced weld metallurgical and mechanical properties for the joints with Zn interlayer. Macrostructural analysis revealed IMC flow variations with and without interlayer. Variation in grain size at different zones is also observed for different interlayers.

(Solid + liquid) phase diagram for (indomethacin + nicotinamide)-methanol or methanol/ethyl acetate mixture and solubility behavior of 1:1 (indomethacin + nicotinamide) co-crystal at T = (298.15 and 313.15) K

International Nuclear Information System (INIS)

Sun, Xiaowei; Yin, Qiuxiang; Ding, Suping; Shen, Zhiming; Bao, Ying; Gong, Junbo; Hou, Baohong; Hao, Hongxun; Wang, Yongli; Wang, Jingkang; Xie, Chuang

2015-01-01

Highlights: • Ternary phase diagrams of (IMC + NCT)-methanol or methanol/ethyl acetate mixture at T = (298.15 and 313.15) K were measured. • The effects of temperature and introduced ethyl acetate on solid phase stability were discussed. • Solubility of (IMC + NCT) cocrystals was first correlated using a model considering solubility product and complexation. • Solubility of (IMC + NCT) cocrystals as a function of co-former concentration was evaluated. - Abstract: (Solid + liquid) equilibrium data for indomethacin (IMC) and nicotinamide (NCT) in both methanol (MeOH) and methanol/ethyl acetate (EA) mixture were determined using a static method at T = (298.15 and 313.15) K under atmospheric pressure. The 1:1 (IMC + NCT) co-crystal and IMC·MeOH were found in both systems under conditions investigated. The solubility of the 1:1 (IMC + NCT) co-crystal was correlated using a mathematical model consisting of both solubility product and a complexation process. Solubility of (IMC + NCT) co-crystals as a function of co-former (NCT) concentration was evaluated. It was found that temperature has a significant effect on the formation of methanol solvate in the systems investigated. Solvate formation could be suppressed either by increasing temperature or using solvent mixtures. Additionally, the solvent mixture could level out the solubility differences between IMC and NCT, resulting in larger and more symmetric regions for the (IMC + NCT) co-crystal, which would be helpful to the development of the co-crystallization process for the 1:1 (IMC + NCT) co-crystal

Verification of Open Interactive Markov Chains

OpenAIRE

Brazdil, Tomas; Hermanns, Holger; Krcal, Jan; Kretinsky, Jan; Rehak, Vojtech

2012-01-01

Interactive Markov chains (IMC) are compositional behavioral models extending both labeled transition systems and continuous-time Markov chains. IMC pair modeling convenience - owed to compositionality properties - with effective verification algorithms and tools - owed to Markov properties. Thus far however, IMC verification did not consider compositionality properties, but considered closed systems. This paper discusses the evaluation of IMC in an open and thus compositional interpretation....

Atrial Fibrillation and Coronary Artery Disease as Risk Factors of Retinal Artery Occlusion: A Nationwide Population-Based Study

Directory of Open Access Journals (Sweden)

Ju-Chuan Yen

2015-01-01

Full Text Available We use Taiwanese national health insurance research database (NHIRD to investigate whether thrombolism (carotid artery disease (CAD as a surrogate or embolism (atrial fibrillation (AF as a surrogate plays roles in later retinal artery occlusion (RAO development and examine their relative weights. The relative risks of RAO between AF and CAD patients and controls were compared by estimating the crude hazard ratio with logistic regression. Kaplan-Meier analysis was used to calculate the cumulative incidence rates of developing RAO, and a log-rank test was used to analyze the differences between the survival curves. Separate Cox proportional hazard regressions were done to compute the RAO-free rate after adjusting for possible confounding factors such as age and sex. The crude hazard ratios were 7.98 for the AF group and 5.27 for the CAD group, and the adjusted hazard ratios were 8.32 and 5.34 for the AF and CAD groups, respectively. The observation time with RAO-free was shorter for AF compared with CAD group (1490 versus 1819 days. AF and CAD were both risk factors for RAO with different hazard ratios. To tackle both AF and CAD is crucial for curbing RAO.

Discrimination of commercial cheeses from fatty acid profiles and phytosterol contents obtained by GC and PCA.

Science.gov (United States)

Kim, Nam Sook; Lee, Ji Hyun; Han, Kyoung Moon; Kim, Ji Won; Cho, Sooyeul; Kim, Jinho

2014-01-15

In this study, a method for discriminating natural mozzarella cheese from cheese substitutes, using fatty acid profiles, phytosterol contents, and statistical comparison, was developed. A total of 27 cheeses were evaluated: eight natural mozzarella cheeses (NMCs), four imitation mozzarella cheeses (IMCs), 12 processed cheeses (PCs) and three mixed cheeses (MCs) composed of NMCs and IMCs. The fatty acid composition of the NMC class was distinct from those of the IMC and MC classes, but statistically similar (pIMCs, but similar (pIMCs, but discrimination between the NMCs and the PCs could not be achieved. Copyright © 2013 Elsevier Ltd. All rights reserved.

The application of "integrated marketing communications" to social marketing and health communication: organizational challenges and implications.

Science.gov (United States)

Nowak, G; Cole, G; Kirby, S; Freimuth, V; Caywood, C

1998-01-01

Influencing consumer behavior is a difficult and often resource-intensive undertaking, with success usually requiring identifying, describing, and understanding target audiences; solid product and/or service positioning relative to competitors; and significant media and communication resources. Integrated marketing communication (IMC) is a new way of organizing and managing persuasive communication tools and functions which involves realigning communications to consider the flow of information from an organization from the viewpoint of end consumers. Although the application of IMC to social marketing remains relatively unexplored, the IMC literature and recent efforts by the US Centers for Disease Prevention and Control suggest that integrated communication approaches have much to offer social marketing and health communication efforts. IMC, IMC and social marketing, and implications of IMC for public and private sector social marketing programs are discussed.

Cooling Crystallization of Indomethacin: Effect of Supersaturation, Temperature and Seeding on Polymorphism and Crystal Size Distribution

DEFF Research Database (Denmark)

Malwade, Chandrakant Ramkrishna; Qu, Haiyan

2018-01-01

In this work, effect of crystallization parameters i.e., supersaturation, seeding, and temperature on polymorphism and crystal size of a non-steroidal anti-inflammatory drug, indomethacin (IMC), was investigated. Firstly, several crystallization solvents (ethanol, methanol, ethyl acetate, acetone...... of IMC from ethanol confirmed that the supersaturation, operating temperature and seeding does affect the polymorphism as well as crystal size distribution of IMC. Fine needle shaped crystals of metastable α-IMC were obtained at 5 °C with high supersaturation even in presence of γ-IMC seeds, while...... rhombic plates like crystals of thermodynamically stable γ-IMC were obtained in remaining experiments. The amount of seed loading only marginally influenced the crystal growth rate and median particle diameter (d50). Particle size analysis of crystals obtained showed bimodal distribution in all...

Sediment texture, distribution and transport on the Ayeyarwady continental shelf, Andaman Sea

Digital Repository Service at National Institute of Oceanography (India)

Rao, P.S.; Ramaswamy, V.; Thwin, S.

. Kluwer Academic Publishers, The Nether- lands, pp. 63–85. Milliman, J.D., Meade, R.H., 1983. World-wide delivery of river sediment to the oceans. J. Geol. 91, 1–21. Ramaswamy, V., Rao, P.S., Rao, K.H., Swe Thwin, Srinivasa Rao, N., Raiker, V., 2004. Tidal...

Effect of Degassing Treatment on the Interfacial Reaction of Molten Aluminum and Solid Steel

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Triyono T.

2017-06-01

Full Text Available The gas porosity is one of the most serious problems in the casting of aluminum. There are several degassing methods that have been studied. During smelting of aluminum, the intermetallic compound (IMC may be formed at the interface between molten aluminum and solid steel of crucible furnace lining. In this study, the effect of degassing treatment on the formations of IMC has been investigated. The rectangular substrate specimens were immersed in a molten aluminum bath. The holding times of the substrate immersions were in the range from 300 s to 1500 s. Two degassing treatments, argon degassing and hexachloroethane tablet degassing, were conducted to investigate their effect on the IMC formation. The IMC was examined under scanning electron microscope with EDX attachment. The thickness of the IMC layer increased with increasing immersion time for all treatments. Due to the high content of hydrogen, substrate specimens immersed in molten aluminum without degasser had IMC layer which was thicker than others. Argon degassing treatment was more effective than tablet degassing to reduce the IMC growth. Furthermore, the hard and brittle phase of IMC, FeAl3, was formed dominantly in specimens immersed for 900 s without degasser while in argon and tablet degasser specimens, it was formed partially.

Journal of Earth System Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Earth System Science. V V S Gurunadha Rao. Articles written in Journal of Earth System Science. Volume 122 Issue 3 June 2013 pp 855-867. Hydrogeochemistry and groundwater quality assessment of Ranipet industrial area, Tamil Nadu, India · G Tamma Rao V V S Gurunadha Rao K ...

Static Analysis of IMC

DEFF Research Database (Denmark)

Skrypnyuk, Nataliya; Nielson, Flemming; Pilegaard, Henrik

2012-01-01

hand, checking properties on process algebraic descriptions is often hard, while “unfolding” them into the Labelled Transition Systems can lead to the infamous state space explosion problem.In this work we use a subtype of Data Flow Analysis on systems defined by finite-state process algebras with CSP...... used as an intermediate representation format, which is more concise than the Labelled Transition System with all the states explicitly represented and more suitable for devising efficient verification algorithms of concurrent systems than their process algebraic descriptions – see, for example...

Jevgenij V. Doc: We do not want to build a monument at Mochovce

International Nuclear Information System (INIS)

Janoska, J.

2004-01-01

In this paper the interview with the General Manager of Inter RAO JES - Jevgenij V. Doc is published. Inter RAO JES applies for the privatisation of Slovenske elektrarne (Slovak Electric - SE). According to the General Manager of Inter RAO JES, the company does not need a foreign partner to provide financial support after the privatisation of SE, but rather it requires a political support. Plans about Bohunice NPP and of completion of the Mochovce NPP as well as of privatisation of the SE by the Inter RAO JES are presented

Codeformation processing of mechanically-dissimilar metal/intermetallic composites

Science.gov (United States)

Marte, Judson Sloan

A systematic and scientific approach has been applied to the study of codeformation processing. A series of composites having mechanically-dissimilar phases were developed in which the high temperature flow behavior of the reinforcement material could be varied independent of the matrix. This was accomplished through the use of a series of intermetallic matrix composites (IMCs) as discontinuous reinforcements in an otherwise conventional metal matrix composite. The IMCs are produced using an in-situ reaction synthesis technique, called the XD(TM) process. The temperature of the exothermic synthesis reaction, called the adiabatic temperature, has been calculated and shown to increase with increasing volume percentage of TiB2 reinforcement. Further, this temperature has been shown to effect the size and spacing of the TiB2, microstructural features which are often used in discontinuous composite strength models. Study of the high temperature flow behavior of the components of the metal/IMC composite is critical to the development of an understanding of codeformation. A series of compression tests performed at 1000° to 1200°C and strain-rates of 10-3 and 10-4 sec-1. Peak flow stresses were used to evaluate the influence of material properties and process conditions. These data were incorporated into phenomenologically-based constitutive equations that have been used to predict the flow behavior. It has been determined that plastic deformation of the IMCs occurs readily, and is largely TiB2 independent, at temperatures approaching the melting point of the intermetallic matrices. Ti-6Al-4V/IMC powder blends were extruded at high temperatures to achieve commensurately deformed microstructures. The results of codeformation processing were analyzed in terms of the plastic strain of the IMC particulates. IMC particle deformation was shown to increase with increasing IMC particle size, volume percentage of IMC, extrusion temperature, homologous temperature, extrusion

Cognitive impairment in neuromyelitis optica spectrum disorders: A comparison of the Wechsler Adult Intelligence Scale-III and the Wechsler Memory Scale Revised with the Rao Brief Repeatable Neuropsychological Battery.

Science.gov (United States)

Fujimori, Juichi; Nakashima, Ichiro; Baba, Toru; Meguro, Yuko; Ogawa, Ryo; Fujihara, Kazuo

2017-12-01

Approximately 55% of patients with neuromyelitis optica spectrum disorder (NMOSD) show cognitive impairment as evaluated using the Rao Brief Repeatable Neuropsychological Battery (BRBN), but this frequency appears to be higher than the frequency of specific brain lesions in NMOSD. We studied whether cognitive impairment could be observed in NMOSD patients with no or minor non-specific brain lesions. We evaluated cognitive function in 12 NMOSD and 14 MS patients using the Wechsler Adult Intelligence Scale-III (WAIS-III), the Wechsler Memory Scale-Revised (WMS-R), and the BRBN. We judged as cognitively impaired patients whose scores were below the average by 2 standard deviations or greater in 2 or more cognitive domains. Cognitive impairment was observed in 5 MS patients (35.7%) and in the only NMOSD patient (8.3%) with symptomatic brain lesions, but not in the other NMOSD patients who had no or minor non-specific brain lesions. Meanwhile, 5 NMOSD (41.7%) and 4 MS (28.6%) patients who had normal cognition according to the WAIS-III and WMS-R were assessed as cognitively impaired by the BRBN (which is not standardized for age). Cognitive function in NMOSD patients with no or mild non-specific brain lesions was preserved according to the WAIS-III and WMS-R.

Chlamydophila spp. infection in horses with recurrent airway obstruction: similarities to human chronic obstructive disease

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Hotzel Helmut

2008-01-01

Full Text Available Abstract Background Recurrent airway obstruction (RAO in horses is a naturally occurring dust-induced disease mainly characterized by bronchiolitis which shows histological and pathophysiological similarities to human chronic obstructive pulmonary disease (COPD. In human COPD previous investigations indicated an association with Chlamydophila psittaci infection. The present study was designed (1 to clarify a possible role of this infectious agent in RAO and (2 to investigate the suitability of this equine disorder as a model for human COPD. Methods Clinico-pathological parameters of a total of 45 horses (25 horses with clinical signs of RAO and 20 clinically healthy controls were compared to histological findings in lung tissue samples and infection by Chlamydiaceae using light microscopy, immunohistochemistry, and PCR. Results Horses with clinical signs of RAO vs. controls revealed more inflammatory changes in histology (p = 0.01, and a higher detection rate of Chlamydia psittaci antigens in all cells (p OmpA sequencing identified Chlamydophila psittaci (n = 9 and Chlamydophila abortus (n = 13 in both groups with no significant differences. Within the group of clinically healthy horses subgroups with no changes (n = 15 and slight inflammation of the small airways (n = 5 were identified. Also in the group of animals with RAO subgroups with slight (n = 16 and severe (n = 9 bronchiolitis could be formed. These four subgroups can be separated in parts by the number of cells positive for Chlamydia psittaci antigens. Conclusion Chlamydophila psittaci or abortus were present in the lung of both clinically healthy horses and those with RAO. Immunohistochemistry revealed acute chlamydial infections with inflammation in RAO horses, whereas in clinically healthy animals mostly persistent chlamydial infection and no inflammatory reactions were seen. Stable dust as the known fundamental abiotic factor in RAO is comparable to smoking in human disease. These

DO22-(Cu,Ni)3Sn intermetallic compound nanolayer formed in Cu/Sn-nanolayer/Ni structures

International Nuclear Information System (INIS)

Liu Lilin; Huang, Haiyou; Fu Ran; Liu Deming; Zhang Tongyi

2009-01-01

The present work conducts crystal characterization by High Resolution Transmission Electron Microscopy (HRTEM) on Cu/Sn-nanolayer/Ni sandwich structures associated with the use of Energy Dispersive X-ray (EDX) analysis. The results show that DO 22 -(Cu,Ni) 3 Sn intermetallic compound (IMC) ordered structure is formed in the sandwich structures at the as-electrodeposited state. The formed DO 22 -(Cu,Ni) 3 Sn IMC is a homogeneous layer with a thickness about 10 nm. The DO 22 -(Cu,Ni) 3 Sn IMC nanolayer is stable during annealing at 250 deg. C for 810 min. The formation and stabilization of the metastable DO 22 -(Cu,Ni) 3 Sn IMC nanolayer are attributed to the less strain energy induced by lattice mismatch between the DO 22 IMC and fcc Cu crystals in comparison with that between the equilibrium DO 3 IMC and fcc Cu crystals.

Development and Analysis of Image Registration Program for the Communication, Ocean, Meteorological Satellite (COMS

Directory of Open Access Journals (Sweden)

Un-Seob Lee

2007-09-01

Full Text Available We developed a software for simulations and analyses of the Image Navigation and Registration (INR system, and compares the characteristics of Image Motion Compensation (IMC algorithms for the INR system. According to the orbit errors and attitude errors, the capabilities of the image distortions are analyzed. The distortions of images can be compensated by GOES IMC algorithm and Modified IMC (MIMC algorithm. The capabilities of each IMC algorithm are confirmed based on compensated images. The MIMC yields better results than GOES IMC although both the algorithms well compensate distorted images. The results of this research can be used as valuable asset to design of INR system for the Communication, Ocean, Meteorological Satellite (COMS.

The How and Why of Interactive Markov Chains

NARCIS (Netherlands)

Hermanns, H.; Katoen, Joost P.; de Boer, F.S; Bonsangue, S.H.; Leuschel, M

2010-01-01

This paper reviews the model of interactive Markov chains (IMCs, for short), an extension of labelled transition systems with exponentially delayed transitions. We show that IMCs are closed under parallel composition and hiding, and show how IMCs can be compositionally aggregated prior to analysis

Study on interfacial reaction between lead-free solders and alternative surface finishes

International Nuclear Information System (INIS)

Siti Rabiatul Aisha; Ourdjini, A.; Saliza Osman

2007-01-01

This study investigates the interfacial reactions occurring during reflow soldering between Sn-Ag-Cu lead-free solder and two surface finishes: electroless nickel/ immersion gold (ENIG) and immersion silver (IAg). The study focuses on interfacial reactions evolution and growth kinetics of intermetallic compounds (IMC) formed during soldering and isothermal ageing at 150 degree Celsius for up to 2000 hours. Optical and scanning electron microscopy were used to measure IMC thickness and examine the morphology of IMC respectively, whereas the IMC phases were identified by energy dispersive X-ray analysis (EDX). The results showed that the IMC formed on ENIG finish is thinner compared to that formed on IAg finish. For IAg surface finish, Cu 6 Sn 5 IMCs with scallop morphology are formed at the solder/ surface finish interface after reflow while a second IMC, Cu 3 Sn was formed between the copper and Cu 6 Sn 5 IMC after the isothermal ageing treatment. For ENIG surface finish both (Cu,Ni) 6 Sn 5 and (Ni,Cu) 3 Sn 4 are formed after soldering. Isothermal aging of the solder joints formed on ENIG finish was found to have a significant effect on the morphology of the intermetallics by transforming to more spherical and denser morphology in addition to increase i their thickness with increased ageing time. (author)

Effects of Ag addition on solid–state interfacial reactions between Sn–Ag–Cu solder and Cu substrate

International Nuclear Information System (INIS)

Yang, Ming; Ko, Yong-Ho; Bang, Junghwan; Kim, Taek-Soo; Lee, Chang-Woo; Li, Mingyu

2017-01-01

Low–Ag–content Sn–Ag–Cu (SAC) solders have attracted much recent attention in electronic packaging for their low cost. To reasonably reduce the Ag content in Pb–free solders, a deep understanding of the basic influence of Ag on the SAC solder/Cu substrate interfacial reaction is essential. Previous studies have discussed the influence of Ag on the interfacial intermetallic compound (IMC) thickness. However, because IMC growth is the joint result of multiple factors, such characterizations do not reveal the actual role of Ag. In this study, changes in interfacial IMCs after Ag introduction were systemically and quantitatively characterized in terms of coarsening behaviors, orientation evolution, and growth kinetics. The results show that Ag in the solder alloy affects the coarsening behavior, accelerates the orientation concentration, and inhibits the growth of interfacial IMCs during solid–state aging. The inhibition mechanism was quantitatively discussed considering the individual diffusion behaviors of Cu and Sn atoms, revealing that Ag inhibits interfacial IMC growth primarily by slowing the diffusion of Cu atoms through the interface. - Highlights: •Role of Ag in IMC formation during Sn–Ag–Cu soldering was investigated. •Ag affects coarsening, crystallographic orientation, and IMC growth. •Diffusion pathways of Sn and Cu are affected differently by Ag. •Ag slows Cu diffusion to inhibit IMC growth at solder/substrate interface.

Effects of Ag addition on solid–state interfacial reactions between Sn–Ag–Cu solder and Cu substrate

Energy Technology Data Exchange (ETDEWEB)

Yang, Ming [Micro-Joining Center, Korea Institute of Industrial Technology (KITECH), Incheon 21999 (Korea, Republic of); Ko, Yong-Ho [Micro-Joining Center, Korea Institute of Industrial Technology (KITECH), Incheon 21999 (Korea, Republic of); Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291, Daehak-ro, Yuseong-gu, Daejeon 34141 (Korea, Republic of); Bang, Junghwan [Micro-Joining Center, Korea Institute of Industrial Technology (KITECH), Incheon 21999 (Korea, Republic of); Kim, Taek-Soo [Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291, Daehak-ro, Yuseong-gu, Daejeon 34141 (Korea, Republic of); Lee, Chang-Woo, E-mail: cwlee@kitech.re.kr [Micro-Joining Center, Korea Institute of Industrial Technology (KITECH), Incheon 21999 (Korea, Republic of); Li, Mingyu, E-mail: myli@hit.edu.cn [Shenzhen Key Laboratory of Advanced Materials, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen 518055 (China)

2017-02-15

Low–Ag–content Sn–Ag–Cu (SAC) solders have attracted much recent attention in electronic packaging for their low cost. To reasonably reduce the Ag content in Pb–free solders, a deep understanding of the basic influence of Ag on the SAC solder/Cu substrate interfacial reaction is essential. Previous studies have discussed the influence of Ag on the interfacial intermetallic compound (IMC) thickness. However, because IMC growth is the joint result of multiple factors, such characterizations do not reveal the actual role of Ag. In this study, changes in interfacial IMCs after Ag introduction were systemically and quantitatively characterized in terms of coarsening behaviors, orientation evolution, and growth kinetics. The results show that Ag in the solder alloy affects the coarsening behavior, accelerates the orientation concentration, and inhibits the growth of interfacial IMCs during solid–state aging. The inhibition mechanism was quantitatively discussed considering the individual diffusion behaviors of Cu and Sn atoms, revealing that Ag inhibits interfacial IMC growth primarily by slowing the diffusion of Cu atoms through the interface. - Highlights: •Role of Ag in IMC formation during Sn–Ag–Cu soldering was investigated. •Ag affects coarsening, crystallographic orientation, and IMC growth. •Diffusion pathways of Sn and Cu are affected differently by Ag. •Ag slows Cu diffusion to inhibit IMC growth at solder/substrate interface.

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Indian Academy of Sciences (India)

IAS Admin

91, 1945 and the author is C R Rao, or, in full, Calyampudi Radhakrishna Rao, writing from the 'Statistical. Laboratory, Calcutta', which is now the Indian Statistical Institute, Kolkata. To get a feel for the issues that Rao's paper addresses, let us look at two very simple examples. The fraction of all the voters who favour a given ...

Bulletin of Materials Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science; Volume 37; Issue 4. Structural, spectroscopic and electrochemical study of V5+ substituted LiTi2(PO4)3 solid electrolyte for lithium-ion batteries. A Venkateswara Rao V Veeraiah A V Prasada Rao B Kishore Babu B Swarna Latha K Rama Rao. Volume 37 Issue 4 June 2014 pp ...

Impaired Cell Cycle Regulation in a Natural Equine Model of Asthma.

Directory of Open Access Journals (Sweden)

Alicja Pacholewska

Full Text Available Recurrent airway obstruction (RAO is a common and potentially debilitating lower airway disease in horses, which shares many similarities with human asthma. In susceptible horses RAO exacerbation is caused by environmental allergens and irritants present in hay dust. The objective of this study was the identification of genes and pathways involved in the pathology of RAO by global transcriptome analyses in stimulated peripheral blood mononuclear cells (PBMCs. We performed RNA-seq on PBMCs derived from 40 RAO affected and 45 control horses belonging to three cohorts of Warmblood horses: two half-sib families and one group of unrelated horses. PBMCs were stimulated with hay dust extract, lipopolysaccharides, a recombinant parasite antigen, or left unstimulated. The total dataset consisted of 561 individual samples. We detected significant differences in the expression profiles between RAO and control horses. Differential expression (DE was most marked upon stimulation with hay dust extract. An important novel finding was a strong upregulation of CXCL13 together with many genes involved in cell cycle regulation in stimulated samples from RAO affected horses, in addition to changes in the expression of several HIF-1 transcription factor target genes. The RAO condition alters systemic changes observed as differential expression profiles of PBMCs. Those changes also depended on the cohort and stimulation of the samples and were dominated by genes involved in immune cell trafficking, development, and cell cycle regulation. Our findings indicate an important role of CXCL13, likely macrophage or Th17 derived, and the cell cycle regulator CDC20 in the immune response in RAO.

Internal Mammary Lymph Node Irradiation Contributes to Heart Dose in Breast Cancer

International Nuclear Information System (INIS)

Chargari, Cyrus; Castadot, Pierre; MacDermed, Dhara; Vandekerkhove, Christophe; Bourgois, Nicolas; Van Houtte, Paul; Magne, Nicolas

2010-01-01

We assessed the impact of internal mammary chain radiotherapy (IMC RT) to the radiation dose received by the heart in terms of heart dose-volume histogram (DVH). Thirty-six consecutive breast cancer patients presenting with indications for IMC RT were enrolled in a prospective study. The IMC was treated by a standard conformal RT technique (50 Gy). For each patient, a cardiac DVH was generated by taking into account the sole contribution of IMC RT. Cardiac HDV were compared according to breast cancer laterality and the type of previous surgical procedure, simple mastectomy or breast conservative therapy (BCT). The contribution of IMC RT to the heart dose was significantly greater for patients with left-sided versus right-sided tumors (13.8% and 12.8% for left-sided tumors versus 3.9% and 4.2% for right-sided tumors in the BCT group and the mastectomy group, respectively; p < 0.0001). There was no statistically significant difference in IMC contribution depending on the initial surgical procedure. IMC RT contributes to cardiac dose for both left-sided and right-sided breast cancers, although the relative contribution is greater in patients with left-sided tumors.

Acute cardiotoxicity with concurrent trastuzumab and radiotherapy including internal mammary chain nodes: A retrospective single-institution study

International Nuclear Information System (INIS)

Shaffer, Richard; Tyldesley, Scott; Rolles, Martin; Chia, Stephen; Mohamed, Islam

2009-01-01

Purpose: To examine the acute cardiotoxicity of internal mammary chain (IMC) irradiation with concurrent trastuzumab. Materials and Methods: Clinical and cardiac function data were collected on 59 patients with early breast cancer who were treated with adjuvant trastuzumab and chemotherapy with or without radiotherapy (often including IMC) at BC Cancer Agency in 2005. Results: Forty-four of fifty-nine patients received adjuvant radiotherapy (RT). Thirteen had left-sided IMC RT. For left-sided RT, IMC inclusion increased the mean percentage dose to 5% of the heart, but the mean doses to 50% and 90% of the heart were similar. Median baseline left ventricular ejection fraction (LVEF) was 62% and similar in all groups. Median absolute decrease in LVEF after RT was 4%, which was not significantly different according to side or inclusion of IMCs. Trastuzumab was stopped in 11 of 59 patients (18.6%) due to decrease in LVEF. After median follow up of 15 months, three patients developed clinical congestive heart failure, none of whom received left-sided IMC RT. Conclusions: There was no excess acute cardiotoxicity observed with the combination of left-sided IMC irradiation and concurrent trastuzumab

Size effects in tin-based lead-free solder joints: Kinetics of bond formation and mechanical characteristics

Science.gov (United States)

Abdelhadi, Ousama Mohamed Omer

Continuous miniaturization of microelectronic interconnects demands smaller joints with comparable microstructural and structural sizes. As the size of joints become smaller, the volume of intermetallics (IMCs) becomes comparable with the joint size. As a result, the kinetics of bond formation changes and the types and thicknesses of IMC phases that form within the constrained region of the bond varies. This dissertation focuses on investigating combination effects of process parameters and size on kinetics of bond formation, resulting microstructure and the mechanical properties of joints that are formed under structurally constrained conditions. An experiment is designed where several process parameters such as time of bonding, temperature, and pressure, and bond thickness as structural chracteristic, are varied at multiple levels. The experiment is then implemented on the process. Scanning electron microscope (SEM) is then utilized to determine the bond thickness, IMC phases and their thicknesses, and morphology of the bonds. Electron backscatter diffraction (EBSD) is used to determine the grain size in different regions, including the bulk solder, and different IMC phases. Physics-based analytical models have been developed for growth kinetics of IMC compounds and are verified using the experimental results. Nanoindentation is used to determine the mechanical behavior of IMC phases in joints in different scales. Four-point bending notched multilayer specimen and four-point bending technique were used to determine fracture toughness of the bonds containing IMCs. Analytical modeling of peeling and shear stresses and fracture toughness in tri-layer four-point bend specimen containing intermetallic layer was developed and was verified and validated using finite element simulation and experimental results. The experiment is used in conjunction with the model to calculate and verify the fracture toughness of Cu6Sn5 IMC materials. As expected two different IMC phases

Strategies for Enhancing Nonlinear Internal Model Control of pH Processes

Energy Technology Data Exchange (ETDEWEB)

Hu, Qiuping.; Rangaiah, G.P. [The National University of Singapore, Singapore (Singapore). Dept. of Chemical and Environmental Engineering

1999-02-01

Control of neutralization processes is very difficult due to nonlinear dynamics, different types of disturbances and modeling errors. The objective of the paper is to evaluate two strategies (augmented internal model control, AuIMC and adaptive internal model control, AdIMC) for enhancing pH control by nonlinear internal model control (NIMC). A NIMC controller is derived directly form input output linearization. The AuIMC is composed of NIMC and an additional loop through which the difference between the process and model outputs is fed back and added to the input of the controller. For the AdIMC, and adaptive law with two tuning parameters is proposed for estimating the unknown parameter. Both AuIMC and AdIMC are extensively tested via simulation for pH neutralization. The theoretical and simulation results show that both the proposed strategies can reduce the effect of modeling errors and disturbances, and thereby enhance the performance of NIMC for pH processes. (author)

Influence of Nickel Thickness and Annealing Time on the Mechanical Properties of Intermetallic Compounds Formed between Cu-Sn Solder and Substrate

Energy Technology Data Exchange (ETDEWEB)

Kim, Yiseul; Kwon, Jeehye; Yoo, Dayoung; Park, Sungkyu; Lee, Dajeong; Lee, Dongyun [Pusan National University, Busan (Korea, Republic of)

2017-03-15

Intermetallic compounds (IMCs) developed on the interface between a solder alloy and its bonding pads are an important factor in the failure of electronic circuits. In this study, the mechanical behaviors of the IMCs formed in the Cu-Ni-Sn ternary alloy system are investigated. Presumably, Ni can act as a diffusion barrier to Cu and Sn to form the IMCs. Detailed analysis of the microstructure is conducted using an electron probe micro-analyzer (EPMA). The addition of Ni softened the IMCs, which is determined based on the fracture toughness increasing (from 0.71 to 1.55 MPa√m) with the Ni layer thickness. However, above a critical amount of Ni involved in the Cu-Sn IMCs, the softening effect is diminished, and this could result from the segregation of Ni inside the IMCs. Therefore, the optimized condition must be determined in order to obtain a positive Ni effect on enhancing the reliability of the electronic circuits.

DO{sub 22}-(Cu,Ni){sub 3}Sn intermetallic compound nanolayer formed in Cu/Sn-nanolayer/Ni structures

Energy Technology Data Exchange (ETDEWEB)

Liu Lilin [School of Physics and Engineering, Sun Yat-Sen University, Guangzhou 510275 (China); Huang, Haiyou [Department of Mechanical Engineering, Hong Kong University of Science and Technology (HKUST) (Hong Kong); Hong Kong - Beijing Joint Research Center, HKUST Fok Ying Tung Graduate School, Nansha, Guangzhou (China); Fu Ran; Liu Deming [ASM Assembly Automation Ltd. (Hong Kong); Zhang Tongyi, E-mail: mezhangt@ust.h [Department of Mechanical Engineering, Hong Kong University of Science and Technology (HKUST) (Hong Kong); Hong Kong - Beijing Joint Research Center, HKUST Fok Ying Tung Graduate School, Nansha, Guangzhou (China)

2009-11-03

The present work conducts crystal characterization by High Resolution Transmission Electron Microscopy (HRTEM) on Cu/Sn-nanolayer/Ni sandwich structures associated with the use of Energy Dispersive X-ray (EDX) analysis. The results show that DO{sub 22}-(Cu,Ni){sub 3}Sn intermetallic compound (IMC) ordered structure is formed in the sandwich structures at the as-electrodeposited state. The formed DO{sub 22}-(Cu,Ni){sub 3}Sn IMC is a homogeneous layer with a thickness about 10 nm. The DO{sub 22}-(Cu,Ni){sub 3}Sn IMC nanolayer is stable during annealing at 250 deg. C for 810 min. The formation and stabilization of the metastable DO{sub 22}-(Cu,Ni){sub 3}Sn IMC nanolayer are attributed to the less strain energy induced by lattice mismatch between the DO{sub 22} IMC and fcc Cu crystals in comparison with that between the equilibrium DO{sub 3} IMC and fcc Cu crystals.

Microstructural evaluation of interfacial intermetallic compounds in Cu wire bonding with Al and Au pads

International Nuclear Information System (INIS)

Kim, Hyung Giun; Kim, Sang Min; Lee, Jae Young; Choi, Mi Ri; Choe, Si Hyun; Kim, Ki Hong; Ryu, Jae Sung; Kim, Sangshik; Han, Seung Zeon; Kim, Won Yong; Lim, Sung Hwan

2014-01-01

A comparative study on the difference in interfacial behavior of thermally aged Cu wire bonding with Al and Au pads was conducted using transmission electron microscopy. During high-temperature lifetime testing of Cu wire bonding with Al and Au pads at 175 °C for up to 2000 h, different growth rates and growth characteristics were investigated in the Cu–Al intermetallic compounds (IMCs), including CuAl 2 , CuAl and Cu 9 Al 4 , and in the Cu–Au IMCs, including (Au,Cu), Cu 3 Au and (Cu,Au). Because of the lower growth rates and greater ductility of Cu–Au IMCs compared to those of Cu–Al IMCs, the Cu wire bonding with the Au pad showed relatively better thermal aging properties of bond pull strength and ball shear strength than those with the Al pad counterpart. In this study, the coherent interfaces were found to retard the growth of IMCs, and a variety of orientation relationships between wire, pad and interfacial IMCs were identified

Evaluation of matrix type mucoadhesive tablets containing indomethacin for buccal application.

Science.gov (United States)

Ikeuchi-Takahashi, Yuri; Sasatsu, Masanaho; Onishi, Hiraku

2013-09-10

Nonsteroidal anti-inflammatory drugs (NSAIDs) are administered for pain relief from oral mucositis. However, the systemic administration of NSAIDs is limited due to systemic side effects. To avoid these side effects and treat local lesions effectively, a matrix type mucoadhesive tablet was developed. A mixture of hard fat, ethylcellulose (EC) and polyethylene glycol (PEG) was used as a matrix base, and indomethacin (IMC) was used as the principal agent. In tablets consisting of hard fat, EC and IMC, the drug release was sustained. In tablets consisting of hard fat, EC, considerable amounts of PEG and IMC, the drug release was relatively increased and IMC existed as the molecular phase or in an amorphous state. The in vitro adhesive force of the tablets consisting of hard fat, EC, considerable amounts of PEG and IMC was significantly increased as compared with the tablets consisting of hard fat and IMC. A significantly high tissue concentration and significantly low plasma concentration were observed after buccal administration of this matrix type mucoadhesive tablet as compared with that after oral administration of IMC. Thus, the matrix type mucoadhesive tablet has good potential as a preparation for the treatment of pain due to oral aphtha. Copyright © 2013 Elsevier B.V. All rights reserved.

Integrated marketing communications in high-quality hotels of central and southern Dalmatia: a study from the perspective of managers and guests

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Maja Šerić

2012-07-01

Full Text Available Although the implementation of Integrated Marketing Communications (IMC has been studied in different contexts and countries all over the world, further contributions are needed to consolidate the concept. Little research has been done on the integration of marketing communications in tourism-related sectors. Moreover, previous studies have focused mainly on managers’ opinions while overlooking consumers’ perceptions of IMC. The purpose of this research is to study in greater detail the IMC concept in the tourism sector, specifically in the hotels of Central and Southern Dalmatia, from a double perspective: managers-guests. Therefore, managers of 15 high-quality hotels and 118 guests were interviewed during April and May 2010. The results of descriptive statistical analysis showed a high degree of IMC implementation in hotels and a high degree of guests’ perceptions of IMC. However, the Mann-Whitney U test revealed small but significant differences between managers’ and guests’ perceptions of some of the IMC items. The findings of this study are expected to provide useful information to hotel managers, who deal with an increasingly competitive marketplace where traditional marketing approaches are no longer sufficient to differentiate themselves from their competitors. Thus, IMC should be considered as a new approach which might enable hotels to gain competitive advantages.

Advanced Monte Carlo methods for thermal radiation transport

Science.gov (United States)

Wollaber, Allan B.

During the past 35 years, the Implicit Monte Carlo (IMC) method proposed by Fleck and Cummings has been the standard Monte Carlo approach to solving the thermal radiative transfer (TRT) equations. However, the IMC equations are known to have accuracy limitations that can produce unphysical solutions. In this thesis, we explicitly provide the IMC equations with a Monte Carlo interpretation by including particle weight as one of its arguments. We also develop and test a stability theory for the 1-D, gray IMC equations applied to a nonlinear problem. We demonstrate that the worst case occurs for 0-D problems, and we extend the results to a stability algorithm that may be used for general linearizations of the TRT equations. We derive gray, Quasidiffusion equations that may be deterministically solved in conjunction with IMC to obtain an inexpensive, accurate estimate of the temperature at the end of the time step. We then define an average temperature T* to evaluate the temperature-dependent problem data in IMC, and we demonstrate that using T* is more accurate than using the (traditional) beginning-of-time-step temperature. We also propose an accuracy enhancement to the IMC equations: the use of a time-dependent "Fleck factor". This Fleck factor can be considered an automatic tuning of the traditionally defined user parameter alpha, which generally provides more accurate solutions at an increased cost relative to traditional IMC. We also introduce a global weight window that is proportional to the forward scalar intensity calculated by the Quasidiffusion method. This weight window improves the efficiency of the IMC calculation while conserving energy. All of the proposed enhancements are tested in 1-D gray and frequency-dependent problems. These enhancements do not unconditionally eliminate the unphysical behavior that can be seen in the IMC calculations. However, for fixed spatial and temporal grids, they suppress them and clearly work to make the solution more

Tangential breast irradiation with or without internal mammary chain irradiation: results of a randomized trial

International Nuclear Information System (INIS)

Kaija, Holli; Maunu, Pitkaenen

1995-01-01

A prospective randomized study was made of 270 patients with unilateral stage I or II invasive breast cancer treated by segmental resection, axillary dissection and radiation at the University Hospital of Tampere, Finland, between 1989 and 1991. The aim of the study was to determine whether there is any advantage or disadvantage if the internal mammary chains (IMC) are included in the radiation target volume. The medial and lateral two-field technique was used and the target volumes were determined randomly either to include the internal mammary chain (IMC-RT) or not (no-IMC-RT). The prevalence of radiation pneumonitis was 16% and there was no significant difference between the IMC- and no-IMC-groups (18 vs. 14%). Skin reactions were equal in both groups. Lung fibrosis was more common in the IMC-RT group. In conclusion: radiation of internal mammary chain after conservative surgery does not lead to an increase in clinically important skin or pulmonary complications. Whether it prevents recurrences or new primaries of the opposite breast is too early to say because of the short follow-up time

Hydrogen-Bonded Polymer-Small Molecule Complexes with Tunable Mechanical Properties.

Science.gov (United States)

Liu, Tianqi; Peng, Xin; Chen, Ya-Nan; Bai, Qing-Wen; Shang, Cong; Zhang, Lin; Wang, Huiliang

2018-03-13

A novel type of polymeric material with tunable mechanical properties is fabricated from polymers and small molecules that can form hydrogen-bonded intermolecular complexes (IMCs). In this work, poly(vinyl alcohol) (PVA)-glycerol hydrogels are first prepared, and then they are dried to form IMCs. The tensile strengths and moduli of IMCs decrease dramatically with increasing glycerol content, while the elongations increase gradually. The mechanical properties are comparable with or even superior to those of common engineering plastics and rubbers. The IMCs with high glycerol content also show excellent flexibility and cold-resistance at subzero temperatures. Cyclic tensile and stress relaxation tests prove that there is an effective energy dissipation mechanism in IMCs and dynamic mechanical analysis confirms their physical crosslinking nature. FTIR and NMR characterizations prove the existence of hydrogen bonding between glycerol and PVA chains, which suppresses the crystallization of PVA from X-ray diffraction measurement. These PVA-glycerol IMCs may find potential applications in barrier films, biomedical packaging, etc., in the future. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

New species and new records of earthworms of the genus Drawida from Kerala part of the Western Ghats biodiversity hotspot, India (Oligochaeta, Moniligastridae).

Science.gov (United States)

Narayanan, S Prasanth; Sathrumithra, S; Christopher, G; Julka, J M

2017-01-01

Two new species of Drawida Michaelsen, 1900, namely Drawida polydiverticulata Narayanan & Julka, sp. n. and Drawida thomasi Narayanan & Julka, sp. n. , are described from material collected from the Indian state of Kerala, which lies in the Western Ghats biodiversity hotspot. Drawida elegans Rao, 1921, Drawida kanarensis Stephenson, 1917, Drawida modesta Rao, 1921, Drawida somavarpatana Rao, 1921, and Drawida thurstoni Gates, 1945 are recorded for the first time from the state.

Comparison of bare and amino modified mesoporous silica@poly(ethyleneimine)s xerogel as indomethacin carrier: Superiority of amino modification.

Science.gov (United States)

Li, Jing; Xu, Lu; Wang, Hongyu; Yang, Baixue; Liu, Hongzhuo; Pan, Weisan; Li, Sanming

2016-02-01

The purpose of this study was to facilely develop amino modified mesoporous silica xerogel synthesized using biomimetic method (B-AMSX) and to investigate its potential ability to be a drug carrier for loading poorly water-soluble drug indomethacin (IMC). For comparison, mesoporous silica xerogel without amino modification (B-MSX) was also synthesized using the same method. The changes of characteristics before and after IMC loading were systemically studied using fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), small angle X-ray scattering (SAXS) and nitrogen adsorption/desorption analysis. The results showed that B-MSX and B-AMSX were spherical nanoparticles with mesoporous structure. Compared with B-MSX, IMC loading capacity of B-AMSX was higher because more drug molecules can be loaded through stronger hydrogen bonding force. DSC and SAXS analysis confirmed the amorphous state of IMC after being loaded into B-MSX and B-AMSX. The in vitro drug release study revealed that B-MSX and B-AMSX improved IMC release significantly, and B-AMSX released IMC a little faster than B-MSX because of larger pore diameter of IMC-AMSX. B-MSX and B-AMSX degraded gradually in dissolution medium evidenced by color reaction and absorbance value, and B-AMSX degraded slower than B-MSX due to amino modification. In conclusion, B-AMSX with superiority of higher loading capacity and enhanced dissolution release can be considered to be a good candidate as drug carrier for IMC. Copyright © 2015 Elsevier B.V. All rights reserved.

Phase relations in the pseudobinary systems RAO3-R2Ti2O7 (R: rare earth element and Y, A: Fe, Ga, Al, Cr and Mn) and syntheses of new compounds R(A1-xTix)O3+x/2 (2/3≤x≤3/4) at elevated temperatures in air

Science.gov (United States)

Brown, Francisco; Jacobo-Herrera, Ivan; Alvarez-Montaño, Victor; Kimizuka, Noboru; Kurashina, Keiji; Michiue, Yuichi; Matsuo, Yoji; Mori, Shigeo; Ikeda, Naoshi; Medrano, Felipe

2017-07-01

Phase relations in the pseudo-binary systems RFeO3-R2Ti2O7 (R: Lu, Ho and Dy), RGaO3-R2Ti2O7 (R: Lu and Er), LuAlO3-Lu2Ti2O7 and RAO3-R2Ti2O7 (R: Lu and Yb. A: Cr and Mn) at elevated temperatures in air were determined by means of a classic quenching method. There exist Lu(Fe1-xTix)O3+x/2, R(Ga1-xTix)O3+x/2 (R: Lu and Er) and Lu(Al1-xTix)O3+x/2 (2/3≤ x≤3/4) having the Yb(Fe1-xTix)O3+x/2-type of crystal structure (x=0.72, space group: R3m, a(Å)=17.9773 and c(Å)=16.978 as a hexagonal setting) in these pseudo binary systems. Eighteen compounds R(A1-xTix)O3+x/2 (R: Lu-Sm and Y, A: Fe, Ga and Al) were newly synthesized and their lattice constants as a hexagonal setting were measured by means of the X-ray powder diffraction method. The R occupies the octahedral site and both A and Ti does the trigonalbipyramidal one in these compounds. Relation between lattice constants for the rhombic R(A1-xTix)O3+x/2 and the monoclinic In(A1-xTix)O3+x/2 are as follows, ah≈5 x bm, ch≈3 x cm x sin β and am=31/2 x bm, where ah and ch are the lattice constants as a hexagonal setting for R(A1-xTix)O3+x/2 and am, bm, cm and β are those of the monoclinic In(A1-xTix)O3+x/2. Crystal structural relationships among α-InGaO3 (hexagonal, high pressure form, space group: P63/mmc), InGaO3 (rhombic, hypothetical), (RAO3)n(BO)m and RAO3(ZnO)m (R: Lu-Ho, Y and In, A: Fe, Ga, and Al, B: divalent cation element, m, n: natural number), the orthorhombic-and monoclinic In(A1-xTix)O3+x/2 (A: Fe, Ga, Al, Cr and Mn) and the hexagonal-and rhombic R(A1-xTix)O3+x/2 (R: Lu-Sm and Y, A: Fe, Ga and Al) are schematically presented. We concluded that the crystal structures of both the α-InGaO3 (high pressure form, hexagonal, space group: P63/mmc) and the hypothetical InGaO3 (rhombic) are the key structures for constructing the crystal structures of these compounds having the cations with CN=5.

Sensibilidade e especificidade de classificação de sobrepeso em adolescentes, Rio de Janeiro

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Vera Chiara

2003-04-01

Full Text Available OBJETIVO: Avaliar a prevalência, sensibilidade e especificidade em detectar adolescentes em risco de obesidade, baseada no Índice de Massa Corporal (IMC. MÉTODOS: Foram avaliados 502 adolescentes de 12 a 18 anos, participantes da pesquisa Nutrição e Saúde do Município do Rio de Janeiro, desenvolvida em 1996. As variáveis do estudo foram: peso, estatura, IMC e dobra subescapular, de acordo com sexo e idade. As classificações para IMC foram comparadas com a classificação pela dobra subescapular no percentil 90 (excesso de adiposidade da população de adolescentes americanos. RESULTADOS: A prevalência de excesso de adiposidade foi mais elevada com a dobra subescapular (P<0,0001 comparada com as classificações do IMC que apresentaram valores aproximados. A especificidade foi superior à sensibilidade com as duas propostas do IMC. O ponto de equilíbrio entre sensibilidade e especificidade foi próximo ao percentil 70 para meninas e meninos menores de 14 anos. Em meninos maiores de 15 anos, o ponto de corte aproximou-se do percentil 50 do IMC. CONCLUSÃO: Ambas classificações do IMC foram mais adequadas para identificar adolescentes sem obesidade, não sendo sensíveis para rastrear excesso de adiposidade.

Serum concentrations of allergen-specific IgE in horses with equine recurrent airway obstruction and healthy controls assessed by ELISA.

Science.gov (United States)

Niedzwiedz, Artur; Jaworski, Zbigniew; Kubiak, Krzysztof

2015-09-01

Equine recurrent airway obstruction (RAO), also known as heaves, is one of the most common respiratory problems in older horses. When RAO-affected horses stay pastured or in a dust-free environment for a prolonged time, clinical signs as well as airway inflammation wane. A number of environmental, immunologic, infectious, and genetic factors play an important role in the pathogenesis of RAO, and the immunologic basis of this disease is still poorly understood. The aim of this study was to investigate the concentrations of allergen-specific IgE in the serum of horses suffering from RAO and healthy controls. The study included a group of 14 adult Polish Konik horses, kept in a standardized environment, and divided into 2 groups: 7 horses which did not have any respiratory problems comprised the control group and 7 horses with a history of RAO constituted the study group. A clinical and laboratory evaluation, endoscopic examination, and bronchoalveolar lavage (BAL) were performed in all horses. Sera of all horses were tested against allergens from 9 molds and 3 mites using the Heska Allercept assay. In the serologic tests, a statistically significant difference between both groups was found for specific IgE against mites, wherein Tyrophagus putrescentia correlated most clearly with RAO. There was no difference between groups for IgE specific against molds. On the basis of our observations and results, we conclude that RAO is associated with increased serum concentrations of specific serum IgE against mites, in particular T putrescentia. © 2015 American Society for Veterinary Clinical Pathology.

Functional diversity through the mean trait dissimilarity: resolving shortcomings with existing paradigms and algorithms.

Science.gov (United States)

de Bello, Francesco; Carmona, Carlos P; Lepš, Jan; Szava-Kovats, Robert; Pärtel, Meelis

2016-04-01

While an increasing number of indices for estimating the functional trait diversity of biological communities are being proposed, there is a growing demand by ecologists to clarify their actual implications and simplify index selection. Several key indices relate to mean trait dissimilarity between species within biological communities. Among them, the most widely used include (a) the mean species pairwise dissimilarity (MPD) and (b) the Rao quadratic entropy (and related indices). These indices are often regarded as redundant and promote the unsubstantiated yet widely held view that Rao is a form of MPD. Worryingly, existing R functions also do not always simplify the use and differentiation of these indices. In this paper, we show various distinctions between these two indices that warrant mathematical and biological consideration. We start by showing an existing form of MPD that considers species abundances and is different from Rao both mathematically and conceptually. We then show that the mathematical relationship between MPD and Rao can be presented simply as Rao = MPD × Simpson, where the Simpson diversity index is defined as 1 - dominance. We further show that this relationship is maintained for both species abundances and presence/absence. This evidence dismantles the paradigm that the Rao diversity is an abundance-weighted form of MPD and indicates that both indices can differ substantially at low species diversities. We discuss the different interpretations of trait diversity patterns in biological communities provided by Rao and MPD and then provide a simple R function, called "melodic," which avoids the unintended results that arise from existing mainstream functions.

Interfacial Reaction During Dissimilar Joining of Aluminum Alloy to Magnesium and Titanium Alloys

Science.gov (United States)

Robson, J. D.; Panteli, A.; Zhang, C. Q.; Baptiste, D.; Cai, E.; Prangnell, P. B.

Ultrasonic welding (USW), a solid state joining process, has been used to produce welds between AA6111 aluminum alloy and AZ31 magnesium alloys or titanium alloy Ti-6Al-4V. The mechanical properties of the welds have been assessed and it has been shown that it is the nature and thickness of the intermetallic compounds (IMCs) at the joint line that are critical in determining joint strength and particularly fracture energy. Al-Mg welds suffer from a very low fracture energy, even when strength is comparable with that of similar metal Mg-Mg welds, due to a thick IMC layer always being formed. It is demonstrated that in USW of Al-Ti alloy the slow interdiffusion kinetics means that an IMC layer does not form during welding, and fracture energy is greater. A model has been developed to predict IMC formation during welding and provide an understanding of the critical factors that determine the IMC thickness. It is predicted that in Al-Mg welds, most of the lMC thickening occurs whilst the IMC regions grow as separate islands, prior to the formation of a continuous layer.

Turunduse tulevik on integratsioon / Mark Ritson

Index Scriptorium Estoniae

Ritson, Mark

2001-01-01

Integreeritud turunduskommunikatsioon (IMC - Integrated Marketing Communications) kui uus turundusmeetod. Tabel ja skeem: sobilikud piirkonnad erinevate IMC tööriistade jaoks; tarbija otsustamise õpikumudel

International dimensions of the IMC

OpenAIRE

Bešlin Marija

2005-01-01

Seems that one of the basic challenge facing marketing organizations today related to shift from traditional functions and operations to the new pattern of the 21st century and the global marketplace. The old traditional models are less and less relevant growing tendency of world market's complexity and increasing competitive efforts ask for "fresh approach" and types of communication with the consumers and other stakeholders. Accordingly, the traditional (linear) model have to be replaced wi...

An improved microculture method for diagnosis of cutaneous leishmaniasis.

Science.gov (United States)

Pagheh, Abdolsattar; Fakhar, Mahdi; Mesgarian, Fatemeh; Gholami, Shirzad; Ahmadpour, Ehsan

2014-12-01

This study evaluated the performance of three diagnostic methods for cutaneous leishmaniasis (CL). Patients who came to the Health Center Laboratory of Gonbad-e-Qabus in Golestan Province, Iran, were enrolled in the study. Skin scraping smear, improved microculture (IMC) and polymerase chain reaction (PCR) were performed. A total of 303 subjects were recruited, among whom 273 subjects fulfilled the criteria for CL. Sensitivity and specificity were 88.8 % (95 % CI = 84.2-92.2 %) and 100.0 % for smears, 98.4 % (95 % CI = 96.1-99.1 %) and 100.0 % for IMC, both of them 100.0 % for PCR. Although, PCR was relatively more sensitive than the IMC, the high correlation (agreement = 96 %, Kappa = 0.82) between IMC and PCR along with the advantages of simplicity, rapidity, adequate sensitivity and as a needle free method, offers the IMC as a valuable alternative diagnostic method for PCR in diagnosis of CL.

Chemorheology of in-mold coating for compression molded SMC applications

Science.gov (United States)

Ko, Seunghyun; Straus, Elliott J.; Castro, Jose M.

2015-05-01

In-mold coating (IMC) is applied to compression molded sheet molding compound (SMC) exterior automotive or truck body panels as an environmentally friendly alternative to make the surface conductive for subsequent electrostatic painting operations. The coating is a thermosetting liquid that when injected onto the surface of the part cures and bonds to provide a smooth conductive surface. In order to optimize the IMC process, it is essential to predict the time available for flow, that is the time before the thermosetting reaction starts (inhibition time) as well as the time when the coating has enough structural integrity so that the mold can be opened without damaging the part surface (cure time). To predict both the inhibition time and the cure time, it is critical to study the chemorheology of IMC. In this paper, we study the chemorheology for a typical commercial IMC system, and show its relevance to both the flow and cure time for the IMC stage during SMC compression molding.

Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development.

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Molly Parkyn Schneider

2017-10-01

Full Text Available Transmission of malaria parasites relies on the formation of a specialized blood form called the gametocyte. Gametocytes of the human pathogen, Plasmodium falciparum, adopt a crescent shape. Their dramatic morphogenesis is driven by the assembly of a network of microtubules and an underpinning inner membrane complex (IMC. Using super-resolution optical and electron microscopies we define the ultrastructure of the IMC at different stages of gametocyte development. We characterize two new proteins of the gametocyte IMC, called PhIL1 and PIP1. Genetic disruption of PhIL1 or PIP1 ablates elongation and prevents formation of transmission-ready mature gametocytes. The maturation defect is accompanied by failure to form an enveloping IMC and a marked swelling of the digestive vacuole, suggesting PhIL1 and PIP1 are required for correct membrane trafficking. Using immunoprecipitation and mass spectrometry we reveal that PhIL1 interacts with known and new components of the gametocyte IMC.

Zintegrowana komunikacja marketingowa. Nowe podejście - propozycja uporządkowania pojęć

OpenAIRE

Rydel, Maciej

2004-01-01

Integrated Marketing Communications (IMC) is something more than Marketing Communications and Promotion. IMC integrates not only traditional (formal) Marketing Communications elements: Advertising, Public Relations, Sales Promotion, Personal Selling and Sponsoring. It integrates all communicates being sent to market environment. The new task of a company, is to manage and integrate all kinds of communicates. The proposed definition is that of H. Fill which states: IMC it is managing dialogue ...

Estado nutricional pregestacional y ganancia de peso materno durante la gestación y su relación con el peso del recién nacido

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Flor de María Grados Valderrama

2003-07-01

Full Text Available Objetivo: Determinar la relación existente entre la ganancia de peso materno durante la gestación con el peso del recién nacido para los diferentes estados nutricionales pregestacionales maternos según el IMC. Material y métodos: Se diseñó un estudio retrospectivo longitudinal descriptivo. Se seleccionaron 1016 mujeres cuyos partos fueron atendidos en el Hospital Nacional Cayetano Heredia entre Enero 1995 a Septiembre 2000 según los criterios de inclusión y exclusión. La población se estratificó en cuatro categorías de acuerdo al IMC pregestacional (Adelgazada: 29. Se realizó un análisis de regresión múltiple que incluyó IMC pregestacional, ganancia ponderal materna, edad materna, número controles prenatales y paridad como variables independientes y peso al nacer como dependiente. Luego, se realizó un análisis de regresión múltiple para cada grupo de IMC pregestacional. Resultados: Se encontró que el IMC pregestacional y la ganancia de peso durante la gestación influyen significantemente en el peso del recién nacido. Para las mujeres adelgazadas, IMC ideal y con sobrepeso; por cada Kg de ganancia ponderal materna durante la gestación el peso del recién nacido se incrementa en 42.15, 34.17 y 21.47 g respectivamente. En el grupo de obesas no se encuentra esta relación. Conclusión: Existe una relación lineal directa entre las variables IMC pregestacional y ganancia de peso materno durante el embarazo con el peso del recién ya sea en forma individual o asociada, para las mujeres adelgazadas, con IMC ideal y con sobrepeso. ( Rev Med Hered 2003; 14:128-133 .

CONSUMO DE BEBIDAS AÇUCARADAS, LEITE E SUA ASSOCIAÇÃO COM O ÍNDICE DE MASSA CORPORAL NA ADOLESCÊNCIA: UMA REVISÃO SISTEMÁTICA

Directory of Open Access Journals (Sweden)

Ana Carolina Corrêa Café

Full Text Available RESUMO Objetivo: Sistematizar as referências da literatura relacionadas à associação entre consumo de bebidas açucaradas não alcoólicas, leite e índice de massa corporal (IMC em adolescentes. Fontes de dados: Realizou-se a pesquisa dos artigos nos portais PubMed (US National Library of Medicine National Institutes of Health e BVS (Biblioteca Virtual em Saúde. Os descritores foram: adolescente, adulto jovem, bebidas, ingestão de líquidos, obesidade, sobrepeso, IMC e estado nutricional. Utilizaram-se os filtros: idade entre 10 e 19 anos e artigos em português e inglês, publicados entre 2011 e 2015. Síntese dos dados: Trinta estudos foram selecionados (22 transversais, 4 coortes, 1 ensaio clínico aleatório, 1 caso-controle e 1 quase experimental. Dos 20 estudos que abordaram bebidas açucaradas em geral, 55% encontraram associação entre consumo e aumento do IMC. Em relação aos estudos sobre a ingestão de refrigerantes, todos apresentaram associação entre consumo e aumento do IMC. Dos estudos sobre leite, somente um demonstrou associação entre consumo e aumento do IMC. Três artigos mostraram proteção entre consumo de leite e aumento do IMC, e três trabalhos não encontraram associação de seu consumo com aumento do IMC. Dezenove estudos possuíam amostras representativas e outros 20 declararam ter amostras aleatórias. Dos artigos com questionários, 84% eram validados. Conclusões: Verifica-se que não há consenso na literatura pesquisada sobre a associação entre consumo de bebidas açucaradas não alcoólicas, leite e IMC de adolescentes.

Material motion corrections for implicit Monte Carlo radiation transport

International Nuclear Information System (INIS)

Gentile, N.A.; Morel, Jim E.

2011-01-01

We describe changes to the Implicit Monte Carlo (IMC) algorithm to include the effects of material motion. These changes assume that the problem can be embedded in a global Lorentz frame. We also assume that the material in each zone can be characterized by a single velocity. With this approximation, we show how to make IMC Lorentz invariant, so that the material motion corrections are correct to all orders of v/c. We develop thermal emission and face sources in moving material and discuss the coupling of IMC to the non- relativistic hydrodynamics equations via operator splitting. We discuss the effect of this coupling on the value of the 'Fleck factor' in IMC. (author)

Effect of Flux onto Intermetallic Compound Formation and Growth

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Idris Siti Rabiatull Aisha

2016-01-01

Full Text Available In this study, the effect of different composition of no-clean flux onto intermetallic compound (IMC formation and growth was investigated. The solder joint between Sn-3Ag-0.5Cu solder alloy and printed circuit board (PCB was made through reflow soldering. They were further aged at 125°C and 150°C for up to 1000 hours. Results showed that fluxes significantly affect the IMC thickness and growth. In addition, during aging, the scallop and columnar morphology of IMC changed to a more planar type for both type of flux during isothermal aging. It was observed that the growth behavior of IMC was closely related to initial soldering condition.

Browse Author Index

African Journals Online (AJOL)

Items 51 - 100 of 141 ... A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All. R. Ramírez-León, A · Ramin, M · Ramirez-Mares, Marco Vinicio · Ramlagan, S · Ramzi, M · Ran, Afou · Rana, M · Rankoana, Sejabaledi Agnes · Rao, K · Rao, Nadendla Rama · Rao, USM · Ras, Sari Abu · Rashid, AZM Manzoor · Raval, SK

A famciclovir + celecoxib combination treatment is safe and efficacious in the treatment of fibromyalgia

Directory of Open Access Journals (Sweden)

Pridgen WL

2017-02-01

Full Text Available William L Pridgen,1 Carol Duffy,2 Judy F Gendreau,3 R Michael Gendreau3 1Innovative Med Concepts, LLC, 2Department of Biological Sciences, University of Alabama, Tuscaloosa, AL, 3Gendreau Consulting, LLC, Poway, CA, USA Objective: Infections and other stressors have been implicated in the development of fibromyalgia. We hypothesized that these stressors could result in recurrent reactivations of latent herpes virus infections, which could lead to the development of fibromyalgia. This study evaluated a famciclovir + celecoxib drug combination (IMC-1, active against suspected herpes virus reactivation and infection, for the treatment of fibromyalgia.Methods: A total of 143 fibromyalgia patients were enrolled at 12 sites in a 16-week, double-blinded, placebo-controlled proof-of-concept trial. Randomized patients received either IMC-1 or placebo in a 1:1 ratio. Outcome measures included a 24-hour recall pain Numerical Rating Scale, the Revised Fibromyalgia Impact Questionnaire (FIQ-R, the Patient’s Global Impression of Change (PGIC questionnaire, the Multidimensional Fatigue Inventory, the NIH Patient-Reported Outcomes Measurement Information System (PROMIS, and the Beck Depression Inventory-II conducted at baseline and weeks 6, 12, and 16 of the study.Results: A significant decrease in fibromyalgia-related pain was observed for patients on IMC-1 treatment versus placebo. PGIC response rates were significantly improved with IMC-1 treatment. Overall, patient self-reported functioning, as measured by the FIQ-R, was significantly improved. Fatigue was also significantly improved as measured by the PROMIS fatigue inventory. The safety profile was encouraging. Despite the celecoxib component of IMC-1, gastrointestinal and nervous system treatment emergent adverse events were reported less frequently in the IMC-1 group, and study completion rates favored IMC-1 treatment.Conclusion: IMC-1 was efficacious and safe in treating symptoms of fibromyalgia

Effects of Fragmented Fe Intermetallic Compounds on Ductility in Al-Si-Mg Alloys.

Science.gov (United States)

Kim, JaeHwang; Kim, DaeHwan

2018-03-01

Fe is intentionally added in order to form the Fe intermetallic compounds (Fe-IMCs) during casting. Field emission scanning electron microscope with energy dispersive spectrometer (EDS) was conducted to understand microstructural changes and chemical composition analyses. The needlelike Fe-IMCs based on two dimensional observation with hundreds of micro size are modified to fragmented particles with the minimum size of 300 nm through clod rolling with 80% thickness reduction. The ratio of Fe:Si on the fragmented Fe-IMCs after 80% reduction is close to 1:1, representing the β-Al5FeSi. The yield and tensile strengths are increased with increasing reduction rate. On the other hand, the elongation is decreased with the 40% reduction, but slightly increased with the 60% reduction. The elongation is dramatically increased over two times for the specimen of 80% reduction compared with that of the as-cast. Fracture behavior is strongly affected by the morphology and size of Fe-IMCs. The fracture mode is changed from brittle to ductile with the microstructure modification of Fe-IMCs.

A technique for estimating the probability of radiation-stimulated failures of integrated microcircuits in low-intensity radiation fields: Application to the Spektr-R spacecraft

Science.gov (United States)

Popov, V. D.; Khamidullina, N. M.

2006-10-01

In developing radio-electronic devices (RED) of spacecraft operating in the fields of ionizing radiation in space, one of the most important problems is the correct estimation of their radiation tolerance. The “weakest link” in the element base of onboard microelectronic devices under radiation effect is the integrated microcircuits (IMC), especially of large scale (LSI) and very large scale (VLSI) degree of integration. The main characteristic of IMC, which is taken into account when making decisions on using some particular type of IMC in the onboard RED, is the probability of non-failure operation (NFO) at the end of the spacecraft’s lifetime. It should be noted that, until now, the NFO has been calculated only from the reliability characteristics, disregarding the radiation effect. This paper presents the so-called “reliability” approach to determination of radiation tolerance of IMC, which allows one to estimate the probability of non-failure operation of various types of IMC with due account of radiation-stimulated dose failures. The described technique is applied to RED onboard the Spektr-R spacecraft to be launched in 2007.

Massive spalling of Cu-Zn and Cu-Al intermetallic compounds at the interface between solders and Cu substrate during liquid state reaction

Science.gov (United States)

Kotadia, H. R.; Panneerselvam, A.; Mokhtari, O.; Green, M. A.; Mannan, S. H.

2012-04-01

The interfacial intermetallic compound (IMC) formation between Cu substrate and Sn-3.8Ag-0.7Cu-X (wt.%) solder alloys has been studied, where X consists of 0-5% Zn or 0-2% Al. The study has focused on the effect of solder volume as well as the Zn or Al concentration. With low solder volume, when the Zn and Al concentrations in the solder are also low, the initial Cu-Zn and Al-Cu IMC layers, which form at the solder/substrate interface, are not stable and spall off, displaced by a Cu6Sn5 IMC layer. As the total Zn or Al content in the system increases by increasing solder volume, stable CuZn or Al2Cu IMCs form on the substrate and are not displaced. Increasing concentration of Zn has a similar effect of stabilizing the Cu-Zn IMC layer and also of forming a stable Cu5Zn8 layer, but increasing Al concentration alone does not prevent spalling of Al2Cu. These results are explained using a combination of thermodynamic- and kinetics-based arguments.

Concurrent nucleation, formation and growth of two intermetallic compounds (Cu6Sn5 and Cu3Sn) during the early stages of lead-free soldering

International Nuclear Information System (INIS)

Park, M.S.; Arróyave, R.

2012-01-01

This study investigates the concurrent nucleation, formation and growth of two intermetallic compounds (IMCs), Cu 6 Sn 5 (η) and Cu 3 Sn (ε), during the early stages of soldering in the Cu–Sn system. The nucleation, formation and growth of the IMC layers is simulated through a multiphase-field model in which the concurrent nucleation of both IMC phases is considered to be a stochastic Poisson process with nucleation rates calculated from classical nucleation theory. CALPHAD thermodynamic models are used to calculate the local contributions to the free energy of the system and the driving forces for precipitation of the IMC phases. The nucleation parameters of the η phase are estimated from experimental results and those of the ε phase are assumed to be similar. A parametric investigation of the effects of model parameters (e.g. grain boundary (GB) diffusion rates, interfacial and GB energies) on morphological evolution and IMC layer growth rate is presented and compared with previous works in which nucleation was ignored . In addition, the resulting growth rates are compared with the available literature and it is found that, for a certain range in the model parameters, the agreement is quite satisfactory. This work provides valuable insight into the dominant mechanisms for mass transport as well as morphological evolution and growth of IMC layers during early stages of Pb-free soldering.

Cognitive behavior therapy for pediatric functional abdominal pain: a randomized controlled trial.

Science.gov (United States)

van der Veek, Shelley M C; Derkx, Bert H F; Benninga, Marc A; Boer, Frits; de Haan, Else

2013-11-01

This randomized controlled trial investigated the effectiveness of a 6-session protocolized cognitive behavior therapy (CBT) compared with 6 visits to a pediatrician (intensive medical care; IMC) for the treatment of pediatric functional abdominal pain (FAP). One hundred four children aged 7 to 18 were randomized to CBT or IMC. CBT was delivered primarily by trained master's degree students in psychology; IMC was delivered by pediatricians or pediatric gastroenterologists. Assessments were performed pretreatment, posttreatment, and at 6- and 12-month follow-up. Primary outcomes were level of abdominal pain (AP) as reported on questionnaires and diaries. Secondary outcomes were other gastrointestinal complaints, functional disability, other somatic complaints, anxiety, depression, and quality of life. Both CBT and IMC resulted in a significant decrease in AP (P .05 for all end points). According to the questionnaire-derived data, 1 year after treatment, 60% of children that received CBT had significantly improved or recovered, versus 56.4% of children receiving IMC, which did not significantly differ (P = .47). These percentages were 65.8% versus 62.8% according to the diary-derived data, which also did not significantly differ (P = .14). Additionally, nearly all secondary outcomes improved after treatment. CBT was equally effective as IMC in reducing AP in children with FAP. More research into the specific working mechanisms of CBT for pediatric FAP is needed.

Impacted Maxillary Canine Prevalence and Its Association with Other Dental Anomalies in a Mexican Population

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José Rubén Herrera-Atoche

2017-01-01

Full Text Available Objective. We quantified the prevalence of impacted maxillary canines (IMC and their association with other dental anomalies (DAs. Materials and Methods. A retrospective study was done with 860 patients 12 to 39 years of age. The prevalence of IMC was calculated and compared by sex. The sample was divided into a control group and an impaction group, and the prevalence was calculated in both for a series of anomalies: agenesis, supernumerary teeth, shape anomalies of the upper laterals (microdontia, peg and barrel shape, and talon cusp, fusion, gemination, other impacted teeth, transposition, and amelogenesis imperfecta. The prevalence values for both groups were compared (Pearson’s χ2 test, p≤0.05. Results. IMC were present in 6.04% of the sample with no difference by sex (p=0.540. Other DAs occurred in 51.92% of the IMC group and in 20.17% of the controls (p<0.05. Significant associations (p<0.05 were identified between IMC and four other DAs: microdontia, barrel shape, other impacted teeth, and transposition. The prevalence of all anomalies was lower in the control group. Conclusion. IMC were seen in 6.04% of patients. Patients with this condition also had a higher prevalence of other DAs. These other anomalies should be used as risk indicators for early diagnosis.

SU-F-T-197: Investigating Optimal Oblique-Beam Arrangement for Bilateral Metallic Prosthesis Prostate Cancer in Pencil Beam Scanning Proton Therapy

Energy Technology Data Exchange (ETDEWEB)

Rana, S; Tesfamicael, B; Park, S [McLaren Proton Therapy Center, Karmanos Cancer Institute at McLaren-Flint, Flint, MI (United States); Zheng, Y; Singh, H; Twyford, T [Procure Proton Therapy Center, Oklahoma City, OK (United States); Cheng, C [Vantage Oncology, West Hills, CA (United States)

2016-06-15

Purpose: The main purpose of this study is to investigate the optimum oblique-beam arrangement for bilateral metallic prosthesis prostate cancer treatment in pencil beam scanning (PBS) proton therapy. Methods: A computed tomography dataset of bilateral metallic prosthesis prostate cancer case was selected for this retrospective study. A total of four beams (rightanterior- oblique [RAO], left-anterior-oblique [LAO], left-posterior-oblique [LPO], and right-posterior-oblique [RPO]) were selected for treatment planning. PBS plans were generated using multi-field-optimization technique for a total dose of 79.2 Gy[RBE] to be delivered in 44 fractions. Specifically, five different PBS plans were generated based on 2.5% ± 2 mm range uncertainty using five different beam arrangements (i)LAO+RAO+LPO+RPO, (ii)LAO+RAO, (iii)LPO+RPO, (iv)RAO+LPO, and (v)LAO+RPO. Each PBS plan was optimized by applying identical dose-volume constraints to the PTV, rectum, and bladder. Treatment plans were then compared based on the dose-volume histograms results. Results: The PTV coverage was found to be greater than 99% in all five plans. The homogeneity index (HI) was found to be almost identical (range, 0.03–0.04). The PTV mean dose was found to be comparable (range, 81.0–81.1 Gy[RBE]). For the rectum, the lowest mean dose (8.0 Gy[RBE]) and highest mean dose (31.1 Gy[RBE]) were found in RAO+LAO plan and LPO+RPO plan, respectively. LAO+RAO plan produced the most favorable dosimetric results of the rectum in the medium-dose region (V50) and high-dose region (V70). For the bladder, the lowest (5.0 Gy[RBE]) and highest mean dose (10.3 Gy[RBE]) were found in LPO+RPO plan and RAO+LAO plan, respectively. Other dosimetric results (V50 and V70) of the bladder were slightly better in LPO+RPO plan than in other plans. Conclusion: Dosimetric findings from this study suggest that two anterior-oblique proton beams arrangement (LAO+RAO) is a more favorable option with the possibility of reducing rectal

Microstructure and Tensile Properties of Sn-1Ag-0.5Cu Solder Alloy Bearing Al for Electronics Applications

Science.gov (United States)

Shnawah, Dhafer Abdul-Ameer; Said, Suhana Binti Mohd; Sabri, Mohd Faizul Mohd; Badruddin, Irfan Anjum; Hoe, Teh Guan; Che, Fa Xing; Abood, Adnan Naama

2012-08-01

This work investigates the effects of 0.1 wt.% and 0.5 wt.% Al additions on bulk alloy microstructure and tensile properties as well as on the thermal behavior of Sn-1Ag-0.5Cu (SAC105) lead-free solder alloy. The addition of 0.1 wt.% Al reduces the amount of Ag3Sn intermetallic compound (IMC) particles and leads to the formation of larger ternary Sn-Ag-Al IMC particles. However, the addition of 0.5 wt.% Al suppresses the formation of Ag3Sn IMC particles and leads to a large amount of fine Al-Ag IMC particles. Moreover, both 0.1 wt.% and 0.5 wt.% Al additions suppress the formation of Cu6Sn5 IMC particles and lead to the formation of larger Al-Cu IMC particles. The 0.1 wt.% Al-added solder shows a microstructure with coarse β-Sn dendrites. However, the addition of 0.5 wt.% Al has a great effect on suppressing the undercooling and refinement of the β-Sn dendrites. In addition to coarse β-Sn dendrites, the formation of large Sn-Ag-Al and Al-Cu IMC particles significantly reduces the elastic modulus and yield strength for the SAC105 alloy containing 0.1 wt.% Al. On the other hand, the fine β-Sn dendrite and the second-phase dispersion strengthening mechanism through the formation of fine Al-Ag IMC particles significantly increases the elastic modulus and yield strength of the SAC105 alloy containing 0.5 wt.% Al. Moreover, both 0.1 wt.% and 0.5 wt.% Al additions worsen the elongation. However, the reduction in elongation is much stronger, and brittle fracture occurs instead of ductile fracture, with 0.5 wt.% Al addition. The two additions of Al increase both solidus and liquidus temperatures. With 0.5 wt.% Al addition the pasty range is significantly reduced and the differential scanning calorimetry (DSC) endotherm curve gradually shifts from a dual to a single endothermic peak.

Influencia do indice de massa corporal no equilibrio e na configuracao plantar em obesos adultos

Directory of Open Access Journals (Sweden)

Liu Chiao Yi

2014-01-01

Full Text Available INTRODUÇÃO: A obesidade é uma doença crônica degenerativa multifatorial que pode levar a alterações do sistema musculoesquelético, como mudança do centro de gravidade e sobrecarga mecânica sobre os membros inferiores. OBJETIVOS: Correlacionar o índice de massa corporal (IMC com o equilíbrio corporal e verificar associação entre o IMC e a configuração plantar. MÉTODOS: Foram avaliados 30 obesos, de ambos os gêneros, com IMC maior ou igual a 30 Kg/m². Inicialmente, os voluntários foram submetidos às avaliações de medidas antropométricas a fim de calcular o valor do IMC. Em seguida, foram submetidos ao teste de equilíbrio corporal estático Balance Error Scoring System (BESS e a plantigrafia para a identificação da impressão plantar. Por meio do método de Viladot, os voluntários foram classificados em grupos: pé plano (GPP, pé cavo (GPC e pé neutro (GPN. A correlação entre as variáveis IMC e BESS foi calculada por meio do coeficiente de correlação linear de Pearson e associação entre o IMC e a configuração plantar foi realizada por meio da análise de variância (Anova. Para todas as análises, nível de significância considerado foi p < 0,05. RESULTADOS: Os valores da correlação entre o IMC e o BESS foram r = - 0,1 e p = 0,59. Os valores da associação do IMC entre GPN - GPP; GPN - GPC; GPP - GPC foram respectivamente: p = 0,76; p = 0,001; p = 0,07. CONCLUSÃO: O índice de massa corporal de adultos obesos não influencia o equilíbrio corporal, porém influencia na configuração plantar.

Model simulation of storm surge potential for Andaman islands

Digital Repository Service at National Institute of Oceanography (India)

Kumar, V.S.; RameshBabu, V.; Babu, M.T.; Dhinakaran, G.; Rajamanickam, G.V.

Hydraulics and Oceanography, the Hydrodynamics Module Reference Manual. DHI Water and Environment, Horsholm, Denmark, 58 p. Dube, S.K., Sinha, P C , Rao, A.D., and Rao, G.S., 1985. Numerical modeling of storm surges in the Arabian Sea, Appl. Math Modelling, 9...

Intermetallic compounds in 3D integrated circuits technology: a brief review.

Science.gov (United States)

Annuar, Syahira; Mahmoodian, Reza; Hamdi, Mohd; Tu, King-Ning

2017-01-01

The high performance and downsizing technology of three-dimensional integrated circuits (3D-ICs) for mobile consumer electronic products have gained much attention in the microelectronics industry. This has been driven by the utilization of chip stacking by through-Si-via and solder microbumps. Pb-free solder microbumps are intended to replace conventional Pb-containing solder joints due to the rising awareness of environmental preservation. The use of low-volume solder microbumps has led to crucial constraints that cause several reliability issues, including excessive intermetallic compounds (IMCs) formation and solder microbump embrittlement due to IMCs growth. This article reviews technologies related to 3D-ICs, IMCs formation mechanisms and reliability issues concerning IMCs with Pb-free solder microbumps. Finally, future outlook on the potential growth of research in this area is discussed.

Intermetallic compounds in 3D integrated circuits technology: a brief review

Science.gov (United States)

Annuar, Syahira; Mahmoodian, Reza; Hamdi, Mohd; Tu, King-Ning

2017-12-01

The high performance and downsizing technology of three-dimensional integrated circuits (3D-ICs) for mobile consumer electronic products have gained much attention in the microelectronics industry. This has been driven by the utilization of chip stacking by through-Si-via and solder microbumps. Pb-free solder microbumps are intended to replace conventional Pb-containing solder joints due to the rising awareness of environmental preservation. The use of low-volume solder microbumps has led to crucial constraints that cause several reliability issues, including excessive intermetallic compounds (IMCs) formation and solder microbump embrittlement due to IMCs growth. This article reviews technologies related to 3D-ICs, IMCs formation mechanisms and reliability issues concerning IMCs with Pb-free solder microbumps. Finally, future outlook on the potential growth of research in this area is discussed.

Interfacial microstructure and mechanical property of Ti6Al4V/A6061 dissimilar joint by direct laser brazing without filler metal and groove

International Nuclear Information System (INIS)

Song, Zhihua; Nakata, Kazuhiro; Wu, Aiping; Liao, Jinsun

2013-01-01

Laser brazing of Ti6Al4V and A6061-T6 alloys with 2 mm thickness was conducted by focusing laser beam on aluminum alloy side, and the effect of laser offset distance on microstructure and mechanical properties of the dissimilar butt joint was investigated. Laser offset has a great influence on the thickness of interfacial intermetallic compound (IMC) layer and the mechanical property of joint. The thickness of interfacial IMC layer is less than 500 nm, and the average tensile strength of the joint reaches 64% of aluminum base material strength, when suitable welding conditions are used. The interfacial IMC is TiAl 3 . The formation of interfacial IMC layer and its effect on mechanical property of the joint are discussed in the present study.

Functional analysis of propeptide as an intramolecular chaperone for in vivo folding of subtilisin nattokinase.

Science.gov (United States)

Jia, Yan; Liu, Hui; Bao, Wei; Weng, Meizhi; Chen, Wei; Cai, Yongjun; Zheng, Zhongliang; Zou, Guolin

2010-12-01

Here, we show that during in vivo folding of the precursor, the propeptide of subtilisin nattokinase functions as an intramolecular chaperone (IMC) that organises the in vivo folding of the subtilisin domain. Two residues belonging to β-strands formed by conserved regions of the IMC are crucial for the folding of the subtilisin domain through direct interactions. An identical protease can fold into different conformations in vivo due to the action of a mutated IMC, resulting in different kinetic parameters. Some interfacial changes involving conserved regions, even those induced by the subtilisin domain, blocked subtilisin folding and altered its conformation. Insight into the interaction between the subtilisin and IMC domains is provided by a three-dimensional structural model. Copyright © 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Inverse grey-box model-based control of a dielectric elastomer actuator

DEFF Research Database (Denmark)

Jones, Richard William; Sarban, Rahimullah

2012-01-01

control performance across the operating range of the DE actuator, a gain scheduling term, which linearizes the operating characteristics of the tubular dielectric elastomer actuator, is developed and implemented in series with the IMC controller. The IMC-based approach is investigated for servo control......An accurate physical-based electromechanical model of a commercially available tubular dielectric elastomer (DE) actuator has been developed and validated. In this contribution, the use of the physical-based electromechanical model to formulate a model-based controller is examined. The choice...... of control scheme was dictated by the desire for transparency in both controller design and operation. The internal model control (IMC) approach was chosen. In this particular application, the inverse of the linearized form of the grey-box model is used to formulate the IMC controller. To ensure consistent...

Fe speciation and Fe/Al ratio in the sediments of southeastern Arabian Sea as an indicator of climate change

Digital Repository Service at National Institute of Oceanography (India)

Pattan, J.N.; Parthiban, G.; Gupta, S.M.; Mir, I.A.

the delivery of dissolved Fe into the Arabian Sea. Some part of the dissolved iron in the continental shelf has been 8 used in the formation of authigenic verdine and glaucony mineral grains (Rao et al., 1993; Thamban and Rao, 2000). The remaining part...

The Twelfth Indian Scientific Expedition to Antarctica: Events and achievements

Digital Repository Service at National Institute of Oceanography (India)

Dhargalkar, V.K.

Chief Minister of Goa on 5 December 1992 at 1945 hours. Other dignitories present on the occasion were Shri Simon D'Souza, Dy. Speaker, Goa Assembly, Dr. P. Rama Rao, Secretary, Shri J.V.R. Prasad Rao, Jt Secretary, Department of Ocean Development, New...

Thermal Cycle Annealing and its Application to Arsenic-Ion Implanted HgCdTe

Science.gov (United States)

2014-06-26

Rao Mulpuri Sina Simingalam, Priyalal Wijewarnasuriya, Mulpuri V. Rao 1720BH c. THIS PAGE The public reporting burden for this collection of...Implanted HgCdTe Sina Simingalama,b,c, Priyalal Wijewarnasuriyab, Mulpuri V. Raoc a. School of Physics, Astronomy and Computational Sciences, George

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 8. Fermion Number Fractionization. Kumar Rao Narendra Sahu Prasanta K ... Author Affiliations. Kumar Rao1 Narendra Sahu1 Prasanta K Panigrahi1. Theoretical Physics Division, Physical Research Laboratory, Ahmedabad 380 009, India ...

An investigation on weld quality characteristics of pulsed current ...

African Journals Online (AJOL)

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generally defined as an iron alloy containing a minimum of 12 wt. ... When steel is held at critical temperature range (600-800 °C) chromium precipitates out of the matrix and forms chrome carbides ..... Prasad K.S., Rao C.S., Rao D.N., 2011a.

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education. Durgesh D Rao. Articles written in Resonance – Journal of Science Education. Volume 3 Issue 7 July 1998 pp 61-70 General Article. Machine Translation - A Gentle Introduction · Durgesh D Rao · More Details Fulltext PDF ...

Marketing Information Products and Services : A Primer for ...

International Development Research Centre (IDRC) Digital Library (Canada)

Marketing Information Products and Services : A Primer for Librarians and Information Professionals. Couverture du livre Marketing Information Products and Services : A Primer for Librarians and Information Professionals. Directeur(s) : Abhinandan K. Jain, Ashok Jambhekar, T.P.Rama Rao et S. Sreenivas Rao. Maison(s) ...

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education. U R Rao. Articles written in Resonance – Journal of Science Education. Volume 6 Issue 12 December 2001 pp 10-18 General Article. Vikram Sarabhai, the Scientist · U R Rao · More Details Fulltext PDF ...

Basement configuration of Visakhapatnam - Paradip continental margin from inversion of magnetic anomalies

Digital Repository Service at National Institute of Oceanography (India)

Rao, M.M.M.; Rao, S.J.; Venkateswarlu, K.; Murthy, K.S.R.; Murthy, I.V.R.; Subrahmanyam, A.S.

. References 1 Curray J R, Emmel F J, Moore D G & Raitt R W, in: Ocean basins and margins, 6 (Plenum, New York) 1982, pp. 399-450. 2 Rao T C S & Murthy K S R, Magnetic surveys over the con- tinental shelf off Visakhapatnam, Mahasagar - Bull Nat Inst... Visakhapatnam, east coast of India, Indian J Earth Sci, 14(1987) 109-113. 8 Murthy K S R, Rao M M M, Rao T C S & Subrahmanyam A S, A comparative study of Werner deconvolution and con- ventional modelling of marine magnetic data, Geophy Res Bull, 25(1987) 152...

B J Rao, TIFR, Mumbai

Indian Academy of Sciences (India)

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With the knowledge of discrete spatial chromosome territory organization within interphase nuclei, our current studyinvestigates the effect of DNA damage at the whole chromosome level. DNA damage,in a dose dependent manner,indeed induces a spatial repositioning of chromosomes specifically with higher gene density.

Angiographic Assessment of the Right Hepatic Artery for Encasement by Hilar Cholangiocarcinoma: Comparison Between Antero-Posterior and Right Anterior Oblique Projections

International Nuclear Information System (INIS)

Furukawa, Hiroyoshi; Iwata, Ryoko; Moriyama, Noriyuki

2001-01-01

Purpose: To evaluate the usefulness of right anterior oblique (RAO) arteriography for evaluating encasement of the right hepatic artery (RHA) by hilar cholangiocarcinoma.Methods: Celiac arteriography was performed in both the antero-posterior (AP) and RAO projection in ten patients with cholangiocarcinoma. The lengths of the arteries between the bifurcation of the anterior and posterior branch of the liver and the following points were measured: (a) the bifurcation of the left and right hepatic artery (AP-LR), (b) the bifurcation of the proper hepatic artery and the gastroduodenal artery (AP-PG). Additionally, image quality in investigating the invasion of the RHA was evaluated.Results: On the AP images, the average lengths of AP-LR and AP-PG were 24.5 ± 5.1 mm and 30.0 ± 4.9 mm, respectively. On RAO images, the lengths were 28.2 ± 4.6 mm and 32.7 ± 4.8 mm, respectively. Every length was different between the two projections (p < 0.01). In 6 of 10 patients with hilar cholangiocarcinoma, images in RAO projections were superior to AP images for evaluation of encasement.Conclusion: We conclude that angiography obtained in the RAO projection yields images that are superior to those obtained in the conventional AP projection for assessment of RHA encasement

Influence of the volume-contact area ratio on the growth behavior of the Cu-Sn intermetallic phase

Science.gov (United States)

Giddaluri, Venkatakamakshi Supraja

Solder Joints play a very important role in electronic packaging industry by serving as mechanical support and provides integrity to the device. The increasing demand for high performance, environmental and economic feasibility and miniaturization led to the development of high density interconnects. With the reduction in the size/standoff height of the solder reliability issues in the surface mount assemblies and packaging structures under various rigorous environments are becoming significant. One of the most important impact factors that affect the solder joint reliability is the growth rate IMC formed between the solder and substrate with reduction in joint size. IMC formation is required to ensure good bonding and connectivity of the device in packaging. However excess IMC growth rate is detrimental to the device from mechanical aspects due to its brittle nature. Thus there is a need to study effect the IMC growth rate behavior with the solder joint size/standoff height. In this present study, two solder joints of different standoff heights and same composition (pure Sn solder) are used subjected to reflow process at 270°C for 1--7 min to study solid liquid interfacial reaction on joint size and the same experiment is repeated with SAC alloy of composition (96.5% Sn, 3.0% Ag, 0.5% Cu) to investigate the effect of joint size and initial copper concentration on IMC growth rate. The IMC thickness of the Sn 15microm solder joint at 1 min and 7 min is found to be 1.52microm and 2.86microm respectively while that of Sn 150microm solder joint is 1.31microm and 3.16 microm. The thickness is high in low standoff height sample at the early stage of reaction with decrease in IMC growth rate as the time of reflow increases. In case of 25microm SAC alloy solder joint the IMC thickness from 1 and 7 min is found to be 2.1microm and 3.5microm while that of 250microm SAC alloy solder joint its 1.43microm and3.235microm. Similar trend is observed but the IMC thickness is more

Mathematical modeling of the in-mold coating process for injection-molded thermoplastic parts

Science.gov (United States)

Chen, Xu

In-Mold Coating (IMC) has been successfully used for many years for exterior body panels made from compression molded Sheet Molding Compound (SMC). The coating material is a single component reactive fluid, designed to improve the surface quality of SMC moldings in terms of functional and cosmetic properties. When injected onto a cured SMC part, IMC cures and bonds to provide a pain-like surface. Because of its distinct advantages, IMC is being considered for application to injection molded thermoplastic parts. For a successful in mold coating operation, there are two key issues related to the flow of the coating. First, the injection nozzle should be located such that the thermoplastic substrate is totally covered and the potential for air trapping is minimized. The selected location should be cosmetically acceptable since it most likely will leave a mark on the coated surface. The nozzle location also needs to be accessible for easy of maintenance. Secondly, the hydraulic force generated by the coating injection pressure should not exceed the available clamping tonnage. If the clamping force is exceeded, coating leakage will occur. In this study, mathematical models for IMC flow on the compressible thermoplastic substrate have been developed. Finite Difference Method (FDM) is first used to solve the 1 dimensional (1D) IMC flow problem. In order to investigate the application of Control Volume based Finite Element Method (CV/FEM) to more complicated two dimensional IMC flow, that method is first evaluated by solving the 1D IMC flow problem. An analytical solution, which can be obtained when a linear relationship between the coating thickness and coating injection pressure is assumed, is used to verify the numerical results. The mathematical models for the 2 dimensional (2D) IMC flow are based on the generalized Hele-Shaw approximation. It has been found experimentally that the power law viscosity model adequately predicts the rheological behavior of the coating

Journal of Astrophysics and Astronomy | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Astrophysics and Astronomy. N. Kameswara Rao. Articles written in Journal of Astrophysics and Astronomy. Volume 26 Issue 2-3 June-September 2005 pp 331-338. High Resolution Stellar Spectroscopy with VBT Echelle Spectrometer · N. Kameswara Rao S. Sriram K. Jayakumar F. Gabriel.

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. G Venkateswara Rao. Articles written in Sadhana. Volume 25 Issue 4 August 2000 pp 367-380. Nonlinear oscillations of laminated plates using an accurate four-node rectangular shear flexible material finite element · Gajbir Singh G Venkateswara Rao · More Details Abstract Fulltext PDF.

Journal of Earth System Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Earth System Science. G Sasibhushana Rao. Articles written in Journal of Earth System Science. Volume 116 Issue 5 October 2007 pp 407-411. GPS satellite and receiver instrumental biases estimation using least squares method for accurate ionosphere modelling · G Sasibhushana Rao.

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education. A R Rao. Articles written in Resonance – Journal of Science Education. Volume 6 Issue 1 January 2001 pp 28-41 General Article. The Football - From Euclid to Soccer it is... A R Rao · More Details Fulltext PDF ...

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. B Jayachander Rao. Articles written in Journal of Chemical Sciences. Volume 119 Issue 5 September 2007 pp 401-407. Reactive chemical dynamics through conical intersections · S Ghosal B Jayachander Rao S Mahapatra · More Details Abstract Fulltext PDF. Reaction ...

Calculation of parameters of technological equipment for deep-sea mining

Science.gov (United States)

Yungmeister, D. A.; Ivanov, S. E.; Isaev, A. I.

2018-03-01

The actual problem of extracting minerals from the bottom of the world ocean is considered. On the ocean floor, three types of minerals are of interest: iron-manganese concretions (IMC), cobalt-manganese crusts (CMC) and sulphides. The analysis of known designs of machines and complexes for the extraction of IMC is performed. These machines are based on the principle of excavating the bottom surface; however such methods do not always correspond to “gentle” methods of mining. The ecological purity of such mining methods does not meet the necessary requirements. Such machines require the transmission of high electric power through the water column, which in some cases is a significant challenge. The authors analyzed the options of transportation of the extracted mineral from the bottom. The paper describes the design of machines that collect IMC by the method of vacuum suction. In this method, the gripping plates or drums are provided with cavities in which a vacuum is created and individual IMC are attracted to the devices by a pressure drop. The work of such machines can be called “gentle” processing technology of the bottom areas. Their environmental impact is significantly lower than mechanical devices that carry out the raking of IMC. The parameters of the device for lifting the IMC collected on the bottom are calculated. With the use of Kevlar ropes of serial production up to 0.06 meters in diameter, with a cycle time of up to 2 hours and a lifting speed of up to 3 meters per second, a productivity of about 400,000 tons per year can be realized for IMC. The development of machines based on the calculated parameters and approbation of their designs will create a unique complex for the extraction of minerals at oceanic deposits.

Evidence-Based Identification of Key Beliefs Explaining Infant Male Circumcision Motivation Among Expectant Parents in Zimbabwe: Targets for Behavior Change Messaging.

Science.gov (United States)

Montaño, Daniel E; Tshimanga, Mufuta; Hamilton, Deven T; Gorn, Gerald; Kasprzyk, Danuta

2018-02-01

Slow adult male circumcision uptake is one factor leading some to recommend increased priority for infant male circumcision (IMC) in sub-Saharan African countries. This research, guided by the integrated behavioral model (IBM), was carried out to identify key beliefs that best explain Zimbabwean parents' motivation to have their infant sons circumcised. A quantitative survey, designed from qualitative elicitation study results, was administered to independent representative samples of 800 expectant mothers and 795 expectant fathers in two urban and two rural areas in Zimbabwe. Multiple regression analyses found IMC motivation among fathers was explained by instrumental attitude, descriptive norm and self-efficacy; while motivation among mothers was explained by instrumental attitude, injunctive norm, descriptive norm, self-efficacy, and perceived control. Regression analyses of beliefs underlying IBM constructs found some overlap but many differences in key beliefs explaining IMC motivation among mothers and fathers. We found differences in key beliefs among urban and rural parents. Urban fathers' IMC motivation was explained best by behavioral beliefs, while rural fathers' motivation was explained by both behavioral and efficacy beliefs. Urban mothers' IMC motivation was explained primarily by behavioral and normative beliefs, while rural mothers' motivation was explained mostly by behavioral beliefs. The key beliefs we identified should serve as targets for developing messages to improve demand and maximize parent uptake as IMC programs are rolled out. These targets need to be different among urban and rural expectant mothers and fathers.

Integrated marketing communications paradigm in digital environment: The five pillars of integration

Directory of Open Access Journals (Sweden)

Rakić Beba

2014-01-01

Full Text Available This paper is focused on the paradigm of integrated marketing communications (IMC in digital environment. The integration is analysed through five aspects. First, integration in terms of media; it means that IMC are performed through the mix of traditional media (print - newspapers, magazines; radio; television; direct-response media - telephone, direct mail, catalogue marketing; billboards; other 'specific media': product - especially brand, packaging; price; place; people; process; physical evidence; traditional/offline consumers - WOM communications and digital media ( the Internet; mobile phones and other mobile devices; digital newspapers and magazines through the Internet and mobile devices; digital radio; digital TV; digital consumers - digital WOM communications. Second, integration in terms of communication methods, it means that IMC are a mix of traditional promotion (advertising, personal selling, public relations & publicity, direct marketing, sales promotion, digital communications/interactions (Internet communications, mobile communications, communications via digital radio and TV and WOM communications/interactions (offline and online. Third, integration in terms of time of communications and possibilities for interaction, it means that IMC are a mix of traditionalstatic communications ('monologue' towards the target audience and dynamic communications ('dialogue' in real time. Fourth, integration in terms of actors, it means that IMC are a mix of communications initiated both by consumers (WOM communications - offline and online/e/digital and organizations. Fifth, integration in terms of content creation, it means that IMC are a mix of communications based on consumer generated content and marketing content (created by organisations.

Distributed Generation Using Indirect Matrix Converter in Reverse Power Mode

DEFF Research Database (Denmark)

Liu, Xiong; Chiang Loh, Poh; Wang, Peng

2013-01-01

Indirect matrix converter (IMC) is an alternative for ac/ac energy conversion, usually operated with a voltage stepped-down gain of only 0.866. For applications like distribution generation where voltage-boost functionality is required, the traditional style of operating the IMC is therefore...... not appropriate. Like most power converters, the operation of the IMC can surely be reversed to produce a boosted gain, but so far its relevant control principles have not been discussed. These challenges are now addressed in this paper with distributed generation suggested as a potential application. Simulation...

P-commutative topological *-algebras

International Nuclear Information System (INIS)

Mohammad, N.; Thaheem, A.B.

1991-07-01

If P(A) denotes the set of all continuous positive functionals on a unital complete Imc *-algebra and S(A) the extreme points of P(A), and if the spectrum of an element χ Ε A coincides with the set {f(χ): f Ε S(A)}, then A is shown to be P-commutative. Moreover, if A is unital symmetric Frechet Q Imc *-algebra, then this spectral condition is, in fact, necessary. Also, an isomorphism theorem between symmetric Frechet P-commutative Imc *-algebras is established. (author). 12 refs

Body fat percentage and body mass index in a probability sample of an adult urban population in Brazil Composición corporal e índice de masa corporal en una muestra probabilística de adultos en Niterói, Río de Janeiro, Brasil Composição corporal e índice de massa corporal em amostra probabilística de adultos de Niterói, Rio de Janeiro, Brasil

Directory of Open Access Journals (Sweden)

Luiz Antonio dos Anjos

2013-01-01

Full Text Available The purpose of the present study was to measure body composition in a probability sample of adults (≥ 20 years living in Niterói, State of Rio de Janeiro, Brazil, and to assess the adequacy of the World Health Organization (WHO recommended body mass index (BMI cut-offs values for identifying obesity in this population. Anthropometric measures and percentage body fat (%BF assessments were taken with 550 fasted individuals (352 women. Obesity was classified according to the WHO recommended BMI cut-off values. %BF predictive equations were developed based on the inverse of BMI. BMI and %BF mean values (standard error were: 25.3kg/m² (0.3 and 38% (0.4 for women and 25.1kg/m² (0.3 and 22.1% (0.6 for men. The predicted %BF values (regression of %BF on the inverse of BMI for each BMI cut-offs of 18.5, 25 and 30kg/m² were: 26.3%, 38.6% and 44.5% for women and 5.6%, 23.2% and 31.5% for men, respectively. The BMI values for the %BF-estimated obesity cut-off values were 20.5 for men and 25.7kg/m² for women. Based on the BMI-%BF relationship, the BMI cut-off values recommended by the WHO are not adequate in identifying obesity in adults from this population.El presente estudio midió la composición corporal en una muestra probabilística de adultos (≥ 20 años de Niterói, Río de Janeiro, Brasil, y evaluó la adecuación de los puntos de corte del índice de masa corporal (IMC de la Organización Mundial de la Salud (OMS para la obesidad en esta población. Las medidas antropométricas y de porcentaje de grasa corporal (%GC por impedancia bioeléctrica se obtuvieron de 550 (352 mujeres adultos en ayunas. La obesidad fue diagnosticada según los puntos de corte de IMC de la OMS. Se desarrollaron ecuaciones de predicción para %GC en función del inverso del IMC. Los valores medios (error patrón de IMC y %GC fueron: 25,3kg/m² (0,3 y 38% (0,4 para mujeres y 25,1kg/m² (0,3 y 22,1% (0,6 para los hombres. Los valores previstos de %GC para IMC de 18

Untitled

Indian Academy of Sciences (India)

Syriaca and Crété (1950) Linum variation of Solanad type of embryo develop- ment in Asclepias curassavica. Rao and Rao (1954) published an account of male and female gametophytes, endosperm and embryo development in. Cryptostegia grandiflora and Caralluma attenuata. Biswas (1957) studied the embryology of ...

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. G Srinivasa Rao. Articles written in Sadhana. Volume 40 Issue 2 April 2015 pp 395-410 Electrical and Computer Sciences. Parametric based morphological transformation for contrast enhancement of color images in poor-lighting · Atluri Srikrishna M Pompapathi G Srinivasa Rao · More Details ...

Proceedings – Mathematical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Proceedings – Mathematical Sciences. B V Rao. Articles written in Proceedings – Mathematical Sciences. Volume 116 Issue 1 February 2006 pp 83-96. On Characterisation of Markov Processes Via Martingale Problems · Abhay G Bhatt Rajeeva L Karandikar B V Rao · More Details Abstract Fulltext PDF.

concentrations, two light regimes of in vitro rooting and ...

African Journals Online (AJOL)

PRECIOUS

2009-11-16

Nov 16, 2009 ... Mahmood AW (1998). Viability of Planting Teak and Sentang in. Malaysia. Forest Research Institute Malaysia. pp. 23-27. Lee SK, Rao AN (1981). In vitro plantlets development in tropical trees-. Calophyllum inophyllum and Eugenia grandis. In. Tissue culture of economically important plants. Rao AN (ed.).

Carotid ultrasonographic and brain computerized tomographic findings in patients with vascular ocular syndromes

Energy Technology Data Exchange (ETDEWEB)

Iwamoto, Toshihiko; Matsushima, Chikage; Shimizu, Souichirou; Takasaki, Masaru; Iwasaki, Takuya; Usui, Masahiko [Tokyo Medical Coll. (Japan)

2002-02-01

To clarify the characteristics of cerebrovascular lesions in subtypes of vascular ocular syndrome, including amaurosis fugax (AF), retinal artery occlusion (RAO), and retinal vein occlusion (RVO), 93 patients with vascular ocular syndrome were studied by means of carotid ultrasonography (US) and brain computerized tomography (CT). The subjects comprised 21 patients with AF, 37 with RAO, and 35 with RVO who were sequentially given these diagnoses by the department of ophthalmology. On the basis of US findings, carotid lesions were defined as the presence of plaque or stenotic changes. CT findings were assessed for the presence and distribution of low-density areas (LDAs). Mean age was similar in each group, ranging from 64.5 to 67.4 years. The RAO group had high rates of men, hypertension, and smokers. US showed that the prevalence of carotid lesions ipsilateral to the affected eye was high in the RAO group and that severe stenosis and ulcerated plaque were present in 28.6% of the AF group and 45.9% of the RAO group. On CT examination, cerebral infarctions appeared as LDAs in about 10% of the patients in each group, and the incidence and distribution of LDAs were similar. Of 13 patients with cerebral infarction, only 2 were presumably due to carotid lesions; the others had a variety of causes. The discrepancy between US and CT findings was attributed to the small number of patients with cerebral infarction, since most patients had visual defects as an initial symptom. Our results suggest that extracranial carotid lesions, considered to be a major risk factor for stroke, should be carefully assessed in patients with AF or RAO to prevent further stroke. (author)

The missing evaluation codes from order domain theory

DEFF Research Database (Denmark)

Andersen, Henning Ejnar; Geil, Olav

The Feng-Rao bound gives a lower bound on the minimum distance of codes defined by means of their parity check matrices. From the Feng-Rao bound it is clear how to improve a large family of codes by leaving out certain rows in their parity check matrices. In this paper we derive a simple lower...... generalized Hamming weight. We interpret our methods into the setting of order domain theory. In this way we fill in an obvious gap in the theory of order domains. The improved codes from the present paper are not in general equal to the Feng-Rao improved codes but the constructions are very much related....

Spi2 gene polymorphism is not associated with recurrent airway obstruction and inflammatory airway disease in thoroughbred horses

Directory of Open Access Journals (Sweden)

Aline Correa da Silva

2011-01-01

Full Text Available The aim was to detect the presence of polymorphisms at exons 1, 2, 3 and 4 of the Spi2 gene, and evaluate a possible association between them and recurrent airway obstruction (RAO or inflammatory airway disease (IAD in thoroughbred horses, through single-strand conformational-polymorphism (SSCP screening. Although polymorphism was not detected in exons 1, 2 and 3, three alleles and six genotypes were identified in exon 4. The frequencies of allele A (0.6388 and genotype AA (0.3888 were higher in horses affected by RAO, although no association was found between polymorphism and horses with either RAO or IAD.

Determining large deflections in rectangular combined loaded ...

Indian Academy of Sciences (India)

(Bisshopp & Drucker 1945; Scott et al 1955; Lau 1982; Rao & Rao 1986; Baker 1993; Lee et al 1993; Frisch-Fay 1962; Fertis 1999). Prathap and Varadan (1976) had calculated large deflections in cantilever beams made of non-linear Ramberg–Osgood type material on which concentrated load effected on the free end.

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education. Sudhakar M Rao. Articles written in Resonance – Journal of Science Education. Volume 12 Issue 5 May 2007 pp 37-40 General Article. Reverse Osmosis · Sudhakar M Rao · More Details Fulltext PDF. Volume 16 Issue 12 December 2011 pp 1333-1336.

Fermi–Dirac Statistics

Indian Academy of Sciences (India)

Subhash Chaturvedi1 Shyamal Biswas2. School of Physics University of Hyderabad C R Rao Road, Gachibowli Hyderabad 500 046, India. University of Hyderabad C R Rao Road, Gachibowli Hyderabad 500 046, India. Resonance – Journal of Science Education. Current Issue : Vol. 23, Issue 4 · Current Issue Volume 23 ...

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. K Veerabhadra Rao. Articles written in Sadhana. Volume 25 Issue 1 February 2000 pp 37-43. A study of correlation technique on pyramid processed images · M Sankar Kishore K Veerabhadra Rao · More Details Abstract Fulltext PDF. The pyramid algorithm is potentially a powerful tool for ...

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. PATTABHI R K RAO. Articles written in Sadhana. Volume 43 Issue 2 February 2018 pp 27. Enhancing multi-document summarization using concepts · PATTABHI R K RAO S LALITHA DEVI · More Details Abstract Fulltext PDF. In this paper we propose a methodology to mine concepts from ...

76 FR 47275 - Postal Service Initiative on Retail Postal Locations

Science.gov (United States)

2011-08-04

.... Id. The RAO initiative applies to postal retail facilities across the country, without limit to geography or population, and is driven by Headquarters. The Commission finds that because the Postal Service... be applied in the RAO initiative. Id. at 19-23. \\3\\ See 39 CFR Part 241. The Request and all...

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education. Rama Rao Nadendla. Articles written in Resonance – Journal of Science Education. Volume 9 Issue 5 May 2004 pp 51-60 General Article. Molecular Modeling: A Powerful Tool for Drug Design and Molecular Docking · Rama Rao Nadendla · More Details Fulltext ...

Chlorophyll a, Phaeopigments and particulate organic carbon in the northern and western Bay of Bengal

Digital Repository Service at National Institute of Oceanography (India)

Radhakrishna, K.; Bhattathiri, P.M.A.; Devassy, V.P.

Distribution of chl a at surface closely corresponds to the surface flow patterns. Integral mean concentration (IMC) of chl a in inshore waters (depth 200 m) is double than that in the offshore waters (depth 200 m) while IMC of particulate organic...

Simulation and Development of Internal Model Control Applications in the Bayer Process

Science.gov (United States)

Colombé, Ph.; Dablainville, R.; Vacarisas, J.

Traditional PID feedback control system is limited in its use in the Bayer cycle due to the important and omnipresent time delays which can lead to stability problems and sluggish response. Advanced modern control techniques are available, but suffer in an industrial environment from a lack of simplicity and robustness. In this respect the Internal Model Control (IMC) method may be considered as an exception. After a brief review of the basic theoretical principles behind IMC, an IMC scheme is developed to work with single-input, single-output, discrete-time, nonlinear systems. Two applications of IMC in the Bayer process, both in simulations and on industrial plants, are then described: control of the caustic soda concentration of the aluminate liquor and control of the A12O3/Na20 caust. ratio of the digested slurry, Finally, the results obtained make this technique quite attractive for the alumina industry.

The formation of intermetallic compounds during interdiffusion of Mg–Al/Mg–Ce diffusion couples

International Nuclear Information System (INIS)

Dai, Jiahong; Jiang, Bin; Li, Xin; Yang, Qingshan; Dong, Hanwu; Xia, Xiangsheng; Pan, Fusheng

2015-01-01

Graphical abstract: Al–Ce intermetallic compounds (IMCs) formed in Mg–Al/Mg–Ce diffusion couples. During the whole diffusion process, Al was the dominant diffusing species, and it substituted for Mg atoms of the Mg–Ce substrate. Five Al–Ce IMCs of Al 4 Ce, Al 11 Ce 3 , Al 3 Ce, Al 2 Ce, and AlCe were formed via the reaction of Al and Ce. - Highlights: • Al–Ce IMCs formation in the Mg–Al/Mg–Ce diffusion couples was studied. • Formation of Al 4 Ce as the first phase was rationalized using the Gibbs free energy. • The activation energy for the growth of the diffusion reaction zones was 36.6 kJ/mol. - Abstract: The formation of Al–Ce intermetallic compounds (IMCs) during interdiffusion of Mg–Al/Mg–Ce diffusion couples prepared by solid–liquid contact method was investigated at 623 K, 648 K and 673 K for 24 h, 48 h and 72 h, respectively. During the whole diffusion process, Al was the dominant diffusing species, and it substituted for Mg of the Mg–Ce substrate. Five Al–Ce IMCs of Al 4 Ce, Al 11 Ce 3 , Al 3 Ce, Al 2 Ce and AlCe were formed via the reaction of Al and Ce. The formation of Al 4 Ce as the first kind of IMC was rationalized on the basis of an effective Gibbs free energy model. The activation energy for the growth of the total diffusion reaction layer was 36.6 kJ/mol

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. B R Shrinivasa Rao. Articles written in Sadhana. Volume 40 Issue 2 April 2015 pp 515-535 Mechanical Sciences. Prediction models for performance and emissions of a dual fuel CI engine using ANFIS · A Adarsh Rai P Srinivasa Pai B R Shrinivasa Rao · More Details Abstract Fulltext PDF.

History | About IASc | Indian Academy of Sciences

Indian Academy of Sciences (India)

O. Siddiqi; 1989 - 1991: Prof. C. N. R. Rao; 1992 - 1994: Prof. R. Narasimha; 1995 - 1997: Prof. P. Rama Rao; 1998 - 2000: Prof. N. Kumar; 2001 - 2003: Dr K. Kasturirangan; 2004 - 2006: Prof. T. V. Ramakrishnan; 2007 - 2009: Prof. D. Balasubramanian; 2010 - 2012: Prof. A. K. Sood; 2013 - 2015: Prof. Dipankar Chatterji ...

Journal of Biosciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Biosciences. Shobha Rao. Articles written in Journal of Biosciences. Volume 26 Issue 4 November 2001 pp 481-489. Nutritional status of the Indian population · Shobha Rao · More Details Abstract Fulltext PDF. High prevalence of low birth weight, high morbidity and mortality in children and poor ...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

VEENA RAO. Articles written in Journal of Genetics. Volume 96 Issue 5 November 2017 pp 717-717 Haldane at 125. Preface · Partha P. Majumder Vidyanand Nanjundiah Veena Rao · More Details Abstract Fulltext PDF. Volume 96 Issue 5 November 2017 pp 765-772 HALDANE AT 125. Haldane's view of natural selection.

Untitled

Indian Academy of Sciences (India)

Karady G, Rogers P 1985 Sadhana 8:135-145. MaassMM, Hufschmidt A, Dorfman R, Thomas HA, Marglin SA, Fair GM 1962 Design ofwater resources systems (Cambridge, Massachusetts. Harvard University Press). Rao PS, Ramaseshan S 1985a Sadhana 8: 179–206. Rao PS, Ramaseshan S 1985b Sadhana 8: 206– ...

Gidon Kremer sai IMC-UNESCO auhinna

Index Scriptorium Estoniae

2001-01-01

Rahvusvaheline muusikanõukogu ja UNESCO kuulutasid tänavu üheks oma ühise muusikaauhinna saajateks Gidon Kremeri, kes esineb ka 21. augustil Estonia kontserdisaalis koos Schleswig-Holsteini festivaliorkestriga

Consistency and refinement for Interval Markov Chains

DEFF Research Database (Denmark)

Delahaye, Benoit; Larsen, Kim Guldstrand; Legay, Axel

2012-01-01

Interval Markov Chains (IMC), or Markov Chains with probability intervals in the transition matrix, are the base of a classic specification theory for probabilistic systems [18]. The standard semantics of IMCs assigns to a specification the set of all Markov Chains that satisfy its interval...

78 FR 57191 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate...

Science.gov (United States)

2013-09-17

... Counsel, IMC Financial Markets dated August 15, 2011 (``IMC Letter''); Michael J. Simon, Secretary, ISE... Initiators a competitive edge to retain a greater percentage of their orders. For the reasons cited above....com . Specifically, daily PIP volumes and average price improvement are available at: http...

Asociación entre hábitos alimentarios e índice de masa corporal normal en soldados chilenos

OpenAIRE

Durán-Agüero, Samuel; Maraboli Ulloa, Daniela; Cubillos-Schmied, Gonzalo; Fernández-Frías, Francisco

2016-01-01

Introducción: Se han evaluado los hábitos alimentarios de diversos grupos etarios y oficios, sin embargo, hay poca información de hábitos alimentarios en soldados. El objetivo del presente estudio es asociar hábitos alimentarios con el índice de masa corporal (IMC) normal en soldados chilenos del Regimiento Buín, Chile. Material y Métodos: Se evaluó a 412 soldados, a cada uno se le aplicó una encuesta alimentaria y una evaluación antropométrica para determinar IMC. Se consideró IMC normal cua...

Effect of Joint Scale and Processing on the Fracture of Sn-3Ag-0.5Cu Solder Joints: Application to Micro-bumps in 3D Packages

Science.gov (United States)

Talebanpour, B.; Huang, Z.; Chen, Z.; Dutta, I.

2016-01-01

In 3-dimensional (3D) packages, a stack of dies is vertically connected to each other using through-silicon vias and very thin solder micro-bumps. The thinness of the micro-bumps results in joints with a very high volumetric proportion of intermetallic compounds (IMCs), rendering them much more brittle compared to conventional joints. Because of this, the reliability of micro-bumps, and the dependence thereof on the proportion of IMC in the joint, is of substantial concern. In this paper, the growth kinetics of IMCs in thin Sn-3Ag-0.5Cu joints attached to Cu substrates were analyzed, and empirical kinetic laws for the growth of Cu6Sn5 and Cu3Sn in thin joints were obtained. Modified compact mixed mode fracture mechanics samples, with adhesive solder joints between massive Cu substrates, having similar thickness and IMC content as actual micro-bumps, were produced. The effects of IMC proportion and strain rate on fracture toughness and mechanisms were investigated. It was found that the fracture toughness G C decreased with decreasing joint thickness ( h Joint). In addition, the fracture toughness decreased with increasing strain rate. Aging also promoted alternation of the crack path between the two joint-substrate interfaces, possibly proffering a mechanism to enhance fracture toughness.

Microcalorimetric determination of the effects of amoxicillin, metronidazole, and their combination on in vitro biofilm.

Science.gov (United States)

Astasov-Frauenhoffer, Monika; Braissant, Olivier; Hauser-Gerspach, Irmgard; Weiger, Roland; Walter, Clemens; Zitzmann, Nicola U; Waltimo, Tuomas

2014-02-01

The mechanism of action of adjuvant antibiotic therapy in the treatment of peri-implantitis is not well understood. The aim of this study is to investigate antibiotic susceptibility of an in vitro biofilm by isothermal microcalorimetry (IMC). Titanium disks containing a 72-hour three-species biofilm (Streptococcus sanguinis DSM20068, Fusobacterium nucleatum ATCC10953, and Porphyromonas gingivalis DSM20709) were placed in a series of IMC ampoules with nutrient agar supplemented with increasing concentrations of amoxicillin, metronidazole, or their combination and incubated anaerobically for 10 days. Lag time and maximum growth rate were determined from continuous heat-flow recordings of metabolic activity. To validate the IMC biofilm results, adherent S. sanguinis and P. gingivalis were incubated anaerobically in medium supplemented with antibiotics at 37°C for 24 hours, and their vitality was determined by live/dead staining, conventional culturing, and IMC. In all biofilm samples incubated with antibiotics, a prolonged lag phase was observed compared with controls (P live/dead staining and conventional culturing. IMC gives new evidence about antibiotic effects on oral biofilms and is more informative than conventional culture and live/dead assays. The combination of antibiotics was found to be more efficient than metronidazole alone; however, only minor differences in growth inhibition were detected compared with amoxicillin alone.

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. K Mallikarjuna Rao. Articles written in Sadhana. Volume 26 Issue 6 December 2001 pp 549-590. A set of pathological tests to validate new finite elements · K Mallikarjuna Rao U Shrinivasa · More Details Abstract Fulltext PDF. The finite element method entails several approximations. Hence it is ...

Journal of Earth System Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Earth System Science. T K Gundu Rao. Articles written in Journal of Earth System Science. Volume 111 Issue 2 June 2002 pp 103-113. Electron spin resonance dating of fault gouge from Desamangalam, Kerala: Evidence for Quaternary movement in Palghat gap shear zone · T K Gundu Rao C P ...

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Comparative efficiencies of three parallel algorithms for nonlinear implicit transient dynamic analysis · A Rama Mohan Rao T V S R Appa Rao B Dattaguru · More Details Abstract Fulltext PDF. The work reported in this paper is motivated by the need to develop portable parallel processing algorithms and codes which can ...

CMS Observes Single Top-Quark

CERN Multimedia

2011-01-01

  One of the many excellent results harvested by CMS from 2010 data. (Figure shows events vs cosine of the angle between lepton and light jets in t rest-frame.)   If you have any comments / suggestions please contact the editors: Marzena Lapka (marzena.lapka@cern.ch) and Achintya Rao (achintya.rao@cern.ch)  

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. G Ranga Rao. Articles written in Journal of Chemical Sciences. Volume 113 Issue 5-6 October-December 2001 pp 651-658. XRD and UV-Vis diffuse reflectance analysis of CeO2-ZrO2 solid solutions synthesized by combustion method · G Ranga Rao H Ranjan Sahu.

A Review: Proteomics in Retinal Artery Occlusion, Retinal Vein Occlusion, Diabetic Retinopathy and Acquired Macular Disorders.

Science.gov (United States)

Cehofski, Lasse Jørgensen; Honoré, Bent; Vorum, Henrik

2017-04-28

Retinal artery occlusion (RAO), retinal vein occlusion (RVO), diabetic retinopathy (DR) and age-related macular degeneration (AMD) are frequent ocular diseases with potentially sight-threatening outcomes. In the present review we discuss major findings of proteomic studies of RAO, RVO, DR and AMD, including an overview of ocular proteome changes associated with anti-vascular endothelial growth factor (VEGF) treatments. Despite the severe outcomes of RAO, the proteome of the disease remains largely unstudied. There is also limited knowledge about the proteome of RVO, but proteomic studies suggest that RVO is associated with remodeling of the extracellular matrix and adhesion processes. Proteomic studies of DR have resulted in the identification of potential therapeutic targets such as carbonic anhydrase-I. Proliferative diabetic retinopathy is the most intensively studied stage of DR. Proteomic studies have established VEGF, pigment epithelium-derived factor (PEDF) and complement components as key factors associated with AMD. The aim of this review is to highlight the major milestones in proteomics in RAO, RVO, DR and AMD. Through large-scale protein analyses, proteomics is bringing new important insights into these complex pathological conditions.

Segmental wall-motion analysis in the right anterior oblique projection: comparison of exercise equilibrium radionuclide ventriculography and exercise contrast ventriculography

International Nuclear Information System (INIS)

Brady, T.J.; Thrall, J.H.; Keyes, J.W. Jr.; Brymer, J.F.; Walton, J.A.; Pitt, B.

1980-01-01

Thirty-nine patients with known or suspected coronary artery disease were studied at rest and during supine bicycle exercise with radionuclide and contrast left ventriculography. Analysis of regional wall motion was made by visual evaluation of the five standard 30 0 right anterior oblique (RAO) wall segments in the contrast images and the corresponding 10 0 RAO radionuclide segments. The radionuclide studies were evaluated independently by three observers using a five-point grading system. The interobserver wall-motion grading agreed completely in more than 80% of segments at rest and exercise, and agreed within one wall-motion grade in more than 95% of segments. The comparison of wall-motion grades between radionuclide and contrast ventriculograms showed complete agreement in 86% of segments at rest and in 78% during exercise, and agreement within one wall-motion grade in 97% of rest and 96% of exercise segments. Visual evaluation of 10 0 RAO rest and exercise radionuclide ventriculograms compares favorably with rest and exercise 30 0 RAO contrast ventriculograms and demonstrates satisfactory interobserver agreement

Better understanding of dissolution behaviour of amorphous drugs by in situ solid-state analysis using Raman spectroscopy

DEFF Research Database (Denmark)

Savolainen, M; Kogermann, K; Heinz, A

2009-01-01

of two amorphous drugs, indomethacin (IMC) and carbamazepine (CBZ). The dissolution rate was higher from amorphous IMC compared to the crystalline alpha- and gamma-forms. However, the dissolution rate started to slow down during the experiment. In situ Raman analysis verified that at that time point...

Relação entre o excesso de peso e a coordenação motora de jovens atletas de atletismo

Directory of Open Access Journals (Sweden)

Jefferson Verbena de Freitas

Full Text Available Resumo O objetivo deste estudo foi verificar a relação entre o índice de massa corporal (IMC e a coordenação motora de jovens atletas de atletismo. Foram avaliados 24 jovens do sexo masculino (12,5 ± 0,6 anos do Projeto Cria-UFJF. Os atletas foram classificados em dois grupos: eutróficos (IMC < 20,6; n = 20 e sobrepeso-obesidade (IMC ≥ 20,6; n = 4. A coordenação motora foi avaliada pelo teste KTK. Verificou-se correlação negativa e estatisticamente significativa entre o IMC e a coordenação motora (r = -0,69; p < 0,001. O grupo sobrepeso-obesidade apresentou menor desempenho no teste de coordenação motora comparado com o grupo eutrófico. Conclui-se que jovens atletas de atletismo com excesso de peso apresentam menor coordenação motora.

Effects of In and Ni Addition on Microstructure of Sn-58Bi Solder Joint

Science.gov (United States)

Mokhtari, Omid; Nishikawa, Hiroshi

2014-11-01

In this study, the effect of adding 0.5 wt.% and 1 wt.% In and Ni to Sn-58Bi solder on intermetallic compound (IMC) layers at the interface and the microstructure of the solder alloys were investigated during reflow and thermal aging by scanning electron microscopy and electron probe micro-analysis. The results showed that the addition of minor elements was not effective in suppressing the IMC growth during the reflow; however, the addition of 0.5 wt.% In and Ni was effective in suppressing the IMC layer growth during thermal aging. The thickening kinetics of the total IMC layer was analyzed by plotting the mean thickness versus the aging time on log-log coordinates, and the results showed the transition point from grain boundary diffusion control to a volume diffusion control mechanism. The results also showed that the minor addition of In can significantly suppress the coarsening of the Bi phase.

Body mass index and its relationship to mental disorders in the Mexican Adolescent Mental Health Survey Índice de masa corporal y su relación con los trastornos mentales en la Encuesta de Salud Mental en Adolescentes de México

Directory of Open Access Journals (Sweden)

Guilherme Borges

2010-04-01

Full Text Available OBJECTIVE: To assess the association between body mass index (BMI and the prevalence of psychiatric disorders among Mexico City adolescents. MATERIAL AND METHODS: Household survey of 3005 adolescents aged 12 to 17 residing in Mexico City in 2005 (response rate = 71%. Face to face interviews were carried out in the homes of participants with informed consent from a parent and/or legal guardian and the assent of the adolescent was obtained. Logistic regression analyses were performed. RESULTS: We only found an association between extremely low BMI and impulse control disorders. Elevated BMI was associated with impulse control disorders only among females. Specific impulse control disorders associated with low BMI included intermittent explosive disorder and conduct disorder. Only intermittent explosive disorder was associated with elevated BMI. CONCLUSION: Among Mexican adolescents, those with extremely high or extremely low BMI were more likely to have impulse control disorders than were adolescents with normal BMI.OBJETIVO: Evaluar la asociación entre el índice de masa corporal (IMC y la prevalencia de trastornos psiquiátricos en adolescentes de la Ciudad de México. MATERIAL Y MÉTODOS: 3005 adolescentes entre 12 y 17 años fueron entrevistados en 2005 (tasa de respuesta =71%. Las entrevistas cara a cara se hicieron en los hogares de los participantes seleccionados después del consentimiento de los padres o tutores. Se utilizó regresión logística. RESULTADOS: Sólo se encontró asociación entre IMC extremadamente bajo y trastornos de control de impulsos. El IMC elevado estuvo asociado con trastornos de control de impulsos sólo en las mujeres. Los trastornos de control de impulsos específicamente relacionados con bajo IMC incluyen el trastorno explosivo intermitente y el trastorno de conducta. El alto IMC estuvo relacionado únicamente con el trastorno explosivo intermitente. CONCLUSIÓN: Entre los adolescentes mexicanos, es m

BMI and self-perceived body shape in Portuguese children

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Eduarda Maria Coelho

2013-01-01

Full Text Available Objetivos: Este estudio examinó la relación entre la percepción subjetiva forma del cuerpo (silueta y el índice de masa corporal (IMC en niños portugueses, de acuerdo con el género, y se determinaron los valores del IMC para cada una de las siluetas. Método: Participó una muestra de 4211 niños, de entre 7 y 10 años de edad. La imagen corporal se evaluó utilizando las Siluetas de Imagen Corporal de Collins de la imagen corporal y se utilizaron las Curvas de Cole et al. para definir la obesidad. Resultados: La media del IMC fue mayor cuando el número de la silueta seleccionado aumentaba, excepto en las siluetas 2 y 7 para los niños y para la 7 en las niñas. La mayoría de las personas que seleccionaron la silueta número 5 o superior eran obesos/as. El ANOVA mostró diferencias significativas en el IMC según las figuras seleccionadas en ambos sexos (p < .001. El coeficiente de correlación entre las siluetas de la imagen corporal y el IMC fue de .54 (p < .001 para la muestra total; de .50 (p < .001 para los niños, y de .57 (p < .001 para las niñas. En los modelos de regresión, el porcentaje de varianza explicada del IMC por las imágenes seleccionadas fue del 25.6% en los varones y del 30.8% en las niñas. Conclusiones: El presente estudio sugiere que en la infancia (7-10 años, la conciencia de la forma del cuerpo no se halla estabilizada, y que las niñas son más precisas que los niños. La forma del cuerpo evaluado por la escala correlacionó moderadamente con el IMC, lo que sugiere que las Siluetas de Collins podrían ser una medida válida para evaluar la obesidad en niños portugueses.

Síndrome da apneia obstrutiva do sono (Saos e sonolência diurna excessiva (SDE: influência sobre os riscos e eventos de queda em idosos

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Renata Afonso Burgos

Full Text Available INTRODUÇÃO: Muitos países vêm experimentando o processo de envelhecimento populacional e a consequente elevação das doenças associadas a ele, como dificuldade de manter o equilíbrio, perdas na qualidade do sono e síndrome da apneia obstrutiva do sono (Saos. OBJETIVOS:Investigar a correlação entre a Saos e sonolência diurna excessiva (SDE com os riscos e eventos de quedas em indivíduos idosos. MATERIAIS E MÉTODOS:Estudo descritivo, comparativo, de corte transversal com amostra de 75 indivíduos com idade igual ou superior a 60 anos, gêneros masculino e feminino. Foram utilizados o mini-exame do estado mental; escalas de depressão geriátrica simplificada; de sonolência de epworth; de avaliação do equilíbrio de tinneti; índice de massa corporal (IMC; registros estabilométricos das oscilações posturais ântero-posterior (AP e médio-lateral (ML. RESULTADOS: Maior prevalência de Saos no gênero masculino. Não foi encontrada correlação com significância estatística (Pearson, p ≤ 0,01 entre as variáveis IMC e estabilometria. Não houve correlação estatisticamente significativa (ANOVA, p ≤ 0,05 entre IMC (subgrupos normal, sobrepeso, graus I, II, III, e IV e estabilometria; entre os graus de severidade de Saos e estabilometria; entre dados estabilométricos de subgrupos de IMC e mesmo grau de severidade de Saos; entre dados estabilométricos de subgrupos de IMC e diferentes graus de Saos; entre os diferentes graus de Saos (GC, G1, (GC e G2, subgrupos de IMC e registros estabilométricos. CONCLUSÃO: Não foram encontrados resultados que corroborassem a hipótese de proporcionalidade entre graus de severidade de Saos, IMC e registro estabilométrico.

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. M D Ghouse. Articles written in Sadhana. Volume 36 Issue 1 February 2011 pp 35-51. Numerical modelling of failure of cement concrete using a unit cell approach · M D Ghouse C Lakshmana Rao B N Rao · More Details Abstract Fulltext PDF. In this paper, a unit cell based approach is followed, ...

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

More Details Fulltext PDF. Volume 4 Issue 1 January 1999 pp 8-22 Series Article. 175 Years of Linear Programming - Pivots in Column Space · Vijay Chandru M R Rao · More Details Fulltext PDF. Volume 4 Issue 5 May 1999 pp 31-39 Series Article. 175 Years of Linear Programming - Pune's Gift · Vijay Chandru M R Rao.

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. S R Koteswara Rao. Articles written in Sadhana. Volume 37 Issue 5 October 2012 pp 587-593. Comparative evaluation of tungsten inert gas and laser beam welding of AA5083-H321 · K Subbaiah M Geetha B Shanmugarajan S R Koteswara Rao · More Details Abstract Fulltext PDF. In this study ...

Ulnar Artery Compression: A Feasible and Effective Approach to Prevent the Radial Artery Occlusion after Coronary Intervention

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Jun Tian

2015-01-01

Full Text Available Background: Radial artery (RA occlusion (RAO is not rare in patients undergoing coronary intervention by transradial approach (TRCI. Predictors of and prevention from RAO have not been systematically studied. This study aimed to analyze the risk factors of the weakness of RA pulsation (RAP and its predictive value for RAO after TRCI, and simultaneously to describe a feasible and effective approach to maintain RA patency. Methods: Between June 2006 and March 2010, all patients who underwent TRCI were classified according to the weakness of RAP after removing compression bandage with confirmation by Doppler ultrasound for the first 30 consecutive patients. Among a total of 2658 patients studied, 187 (7% patients having a weaker RAP were prospectively monitored. At 1 h after bandage removal, the ulnar artery in puncture side of all patients was blocked with manual compression to favor brachial and collateral artery blood flow through the RA until a good RAP was restored. The primary analysis was the occurrence of RAO. Results: Doppler ultrasound demonstrated the significant reduction of both systolic velocity (61.24 ± 3.95 cm/s vs. 72.31 ± 3.57 cm/s and diastolic velocity (1.83 ± 0.32 cm/s vs. 17.77 ± 3.97 cm/s in RA at access side as compared to the contralateral RA (all P < 0.001, but these velocities in ipsilateral ulnar artery (81.2 ± 2.16 cm/s and 13.1 ± 2.86 cm/s, respectively increased profoundly. The average time of ulnar artery compression was 4.1 ± 1.2 h (ranged 2.5-6.5 h. There were two patients experienced persistent RAO with a success rate of 98.9% and RAO in 0.075% of patients after ulnar artery compression was applied. The pulsation of the ulnar artery after compression was removed had not been influenced by the compression. Conclusions: After intervention using TRCI approach, the presence of a weaker RAP is an indicator of imminent RAO. The continuing compression of ipsilateral ulnar artery is an effective approach to

Social Impact "Buycotts": A Tool for Innovation, Impact, and Engagement to Teach Integrated Marketing Communications

Science.gov (United States)

Holland, Jonna

2016-01-01

A novel concept for an integrated marketing communications (IMC) semester project succeeded in meeting or exceeding course learning objectives while increasing social impact and community engagement. Partnering with a selected business and a synergistic community cause, student teams developed and implemented an IMC plan to motivate consumers to…

Probiotic properties of Lactobacillus rhamnosus and Lactobacillus paracasei isolated from human faeces.

Science.gov (United States)

Verdenelli, Maria Cristina; Ghelfi, Francesca; Silvi, Stefania; Orpianesi, Carla; Cecchini, Cinzia; Cresci, Alberto

2009-09-01

The possibility of using microbes to maintain health, and to prevent or treat disease is a topic as old as microbiology. The research of novel probiotic strains is important in order to satisfy the increasing request of the market and to obtain functional products in which the probiotic cultures are more active and with better probiotic characteristics than those already present on the market. In this study, the probiotic potential of Lactobacillus strains isolated from Italian elderly human faeces was investigated. The Lactobacillus strains were identified and examined for resistance to gastric acidity and bile toxicity, adhesion to HT-29 cells, antimicrobial activities, antibiotic susceptibility and plasmid profile. Survival of the strains through human intestine was examined in a 3 months human feeding trial. Two strains, Lactobacillus rhamnosus IMC 501 and Lactobacillus paracasei IMC 502, tolerated well low pH and bile acids. In antimicrobial activity assays, both strains showed inhibitory properties towards selected potential harmful microorganisms, particularly against Candida albicans. The two selected strains expressed high in vitro adherence to HT-29 cells increasing this characteristic when they are used in combination and they were resistant to vamcomycin, colistin sulphate, gentamicin, oxolinic acid and kanamycin. Moreover, the two strains could be recovered from stools of volunteers after the feeding trials. Lactobacillus rhamnosus IMC 501 and L. paracasei IMC 502 present favourable strain-specific properties for their utilisation as probiotics in functional foods and the high adhesion ability of the L. rhamnosus IMC 501 and L. paracasei IMC 502 used in combination, confirmed by both in vitro and in vivo study, indicate that the two bacterial strains could be used as health-promoting bacteria.

Solid-State NMR Investigation of Drug-Excipient Interactions and Phase Behavior in Indomethacin-Eudragit E Amorphous Solid Dispersions.

Science.gov (United States)

Lubach, Joseph W; Hau, Jonathan

2018-02-20

To investigate the nature of drug-excipient interactions between indomethacin (IMC) and methacrylate copolymer Eudragit® E (EE) in the amorphous state, and evaluate the effects on formulation and stability of these amorphous systems. Amorphous solid dispersions containing IMC and EE were spray dried with drug loadings from 20% to 90%. PXRD was used to confirm the amorphous nature of the dispersions, and DSC was used to measure glass transition temperatures (T g ). 13 C and 15 N solid-state NMR was utilized to investigate changes in local structure and protonation state, while 1 H T 1 and T 1ρ relaxation measurements were used to probe miscibility and phase behavior of the dispersions. T g values for IMC-EE solid dispersions showed significant positive deviations from predicted values in the drug loading range of 40-90%, indicating a relatively strong drug-excipient interaction. 15 N solid-state NMR exhibited a change in protonation state of the EE basic amine, with two distinct populations for the EE amine at -360.7 ppm (unprotonated) and -344.4 ppm (protonated). Additionally, 1 H relaxation measurements showed phase separation at high drug load, indicating an amorphous ionic complex and free IMC-rich phase. PXRD data showed all ASDs up to 90% drug load remained physically stable after 2 years. 15 N solid-state NMR experiments show a change in protonation state of EE, indicating that an ionic complex indeed forms between IMC and EE in amorphous solid dispersions. Phase behavior was determined to exhibit nanoscale phase separation at high drug load between the amorphous ionic complex and excess free IMC.

Inhibition of EGFR or IGF-1R signaling enhances radiation response in head and neck cancer models but concurrent inhibition has no added benefit

International Nuclear Information System (INIS)

Raju, Uma; Molkentine, David P; Valdecanas, David R; Deorukhkar, Amit; Mason, Kathryn A; Buchholz, Thomas A; Meyn, Raymond E; Ang, Kie-Kian; Skinner, Heath

2015-01-01

Interaction between the epidermal growth factor receptor (EGFR) and the insulin-like growth factor receptor (IGF-1R) has been well established in many cancer types. We investigated the effects of cetuximab (EGFR antibody) and IMC-A12 (IGF-1R antibody) on the response of head and neck squamous cell carcinoma (HNSCC) to radiation therapy (RT). The effects of cetuximab and IMC-A12 on cell viability and radiosensitivity were determined by clonogenic cell survival assay. Formation of nuclear γ-H2AX and 53BP1 foci was monitored by immunofluorescence. Alterations in target signaling were analyzed by Western blots. In vivo tumor growth delay assay was performed to determine the efficacy of triple therapy with IMC-A12, cetuximab, and RT. In vitro data showed that cetuximab differentially affected the survival and the radiosensitivity of HNSCC cells. Cetuximab suppressed DNA repair that was evident by the prolonged presence of nuclear γ-H2AX and 53BP1 foci. IMC-A12 did not have any effect on the cell survival. However, it increased the radiosensitivity of one of the cell lines. EGFR inhibition increased IGF-1R expression levels and also the association between EGFR and IGF-1R. Addition of IMC-A12 to cetuximab did not increase the radiosensitivity of these cells. Tumor xenografts exhibited enhanced response to RT in the presence of either cetuximab or IMC-A12. Concurrent treatment regimen failed to further enhance the tumor response to cetuximab and/or RT. Taken together our data suggest that concomitant inhibition of both EGFR and IGF-1R pathways did not yield additional therapeutic benefit in overcoming resistance to RT

Aging treatment characteristics of solder bump joint for high reliability optical module

International Nuclear Information System (INIS)

Kim, Kyung-Seob; Yu, Chung-Hee; Yang, Jun-Mo

2004-01-01

The joint strength and fracture surfaces of Sn-37 mass% Pb and Au stud bumps for photo diode packages after isothermal aging testing were studied experimentally. Al/Au stud bumps and Cu/Sn-37 mass% Pb solders were adopted, and aged for up to 900 h to analyze the effect of intermetallic compound (IMC). The joint strength decreased with aging time. The diffraction patterns of Cu 6 Sn 5 , scallop-shaped IMCs, and planar-shaped Cu 3 Sn were characterized using transmission electron microscopy (TEM). The formation of Kirkendall voids and the growth of IMCs at the solder were found to be a possible mechanism for joint strength reduction

In situ amorphisation of indomethacin with Eudragit® E during dissolution

DEFF Research Database (Denmark)

Priemel, Petra A; Laitinen, Riikka; Grohganz, Holger

2013-01-01

at pH 6.8 at which IMC but not the polymer is soluble. Compacts changed their colour from white to yellow indicating amorphisation of IMC. X-ray powder diffractometry (XRPD) confirmed the amorphisation and only one glass transition temperature was observed (58.1 °C, 54.4 °C, and 50.1 °C for the 3:1, 1......In this study, the possibility of utilising in situ crystalline-to-amorphous transformation for the delivery of poorly water soluble drugs was investigated. Compacts of physical mixtures of γ-indomethacin (IMC) and Eudragit® E in 3:1, 1:1 and 1:3 (w/w) ratios were subjected to dissolution testing...

Plasma flow to a surface using the iterative Monte Carlo method

International Nuclear Information System (INIS)

Pitcher, C.S.

1994-01-01

The iterative Monte Carlo (IMC) method is applied to a number of one-dimensional plasma flow problems, which encompass a wide range of conditions typical of those present in the boundary of magnetic fusion devices. The kinetic IMC method of solving plasma flow to a surface consists of launching and following particles within a grid of 'bins' into which weights are left according to the time a particle spends within a bin. The density and potential distributions within the plasma are iterated until the final solution is arrived at. The IMC results are compared with analytical treatments of these problems and, in general, good agreement is obtained. (author)

Prevalencia y factores de riesgo de sobrepeso en colegialas de 12 a 19 años en una región semiurbana del Ecuador

Directory of Open Access Journals (Sweden)

José Castro Burbano

Full Text Available RESUMEN OBJETIVOS: Determinar la prevalencia y los factores de riesgo de sobrepeso en colegialas de 12 a 19 años de una región semiurbana del Ecuador e investigar la posible relación del índice de masa corporal (IMC de cada adolescente con su actividad física e ingestión calórica y de macronutrientes, así como con el IMC estimado de los padres. MÉTODOS: De enero a abril de 2001 se realizó un estudio de corte transversal que incluyó a 302 alumnas adolescentes de 12 a 19 años de cuatro colegios secundarios de Cumbayá y Tumbaco (14 km al nororiente de Quito. Los colegios y las alumnas fueron seleccionados por muestreo aleatorio sistemático y a todas las participantes se les tomaron y registraron las medidas antropométricas (peso, talla, circunferencia de la cintura y circunferencia de la cadera y su ingestión calórica total y de macronutrientes mediante un instrumento de recordatorio de 24 horas. También se les administró un cuestionario sobre su actividad física y se estimó el IMC de los padres. RESULTADOS: De las participantes, 8,3% presentaron sobrepeso y 0,7%, obesidad. En 40,7% de las primeras, el sobrepeso tenía distribución gluteofemoral; en 51,9%, distribución intermedia; y en 3,7%, distribución abdominal. Se observó una correlación inversa entre el IMC de las adolescentes y su actividad física e ingestión energética (P < 0,05, mientras que fue directa la correlación entre el IMC de cada adolescente y el IMC estimado de la madre (P < 0,05. CONCLUSIONES: Los resultados indicaron que la prevalencia de sobrepeso coincidía con la hallada en un estudio nacional pero que era menor que la correspondiente a informes de países industrializados y de otros países latinoamericanos. Los factores más influyentes sobre el IMC de la adolescente fueron la actividad física y el IMC de la madre, independientemente de la ingestión energética total y de la composición de la dieta.

Prevalencia y factores de riesgo de sobrepeso en colegialas de 12 a 19 años en una región semiurbana del Ecuador

Directory of Open Access Journals (Sweden)

Burbano José Castro

2003-01-01

Full Text Available RESUMEN OBJETIVOS: Determinar la prevalencia y los factores de riesgo de sobrepeso en colegialas de 12 a 19 años de una región semiurbana del Ecuador e investigar la posible relación del índice de masa corporal (IMC de cada adolescente con su actividad física e ingestión calórica y de macronutrientes, así como con el IMC estimado de los padres. MÉTODOS: De enero a abril de 2001 se realizó un estudio de corte transversal que incluyó a 302 alumnas adolescentes de 12 a 19 años de cuatro colegios secundarios de Cumbayá y Tumbaco (14 km al nororiente de Quito. Los colegios y las alumnas fueron seleccionados por muestreo aleatorio sistemático y a todas las participantes se les tomaron y registraron las medidas antropométricas (peso, talla, circunferencia de la cintura y circunferencia de la cadera y su ingestión calórica total y de macronutrientes mediante un instrumento de recordatorio de 24 horas. También se les administró un cuestionario sobre su actividad física y se estimó el IMC de los padres. RESULTADOS: De las participantes, 8,3% presentaron sobrepeso y 0,7%, obesidad. En 40,7% de las primeras, el sobrepeso tenía distribución gluteofemoral; en 51,9%, distribución intermedia; y en 3,7%, distribución abdominal. Se observó una correlación inversa entre el IMC de las adolescentes y su actividad física e ingestión energética (P < 0,05, mientras que fue directa la correlación entre el IMC de cada adolescente y el IMC estimado de la madre (P < 0,05. CONCLUSIONES: Los resultados indicaron que la prevalencia de sobrepeso coincidía con la hallada en un estudio nacional pero que era menor que la correspondiente a informes de países industrializados y de otros países latinoamericanos. Los factores más influyentes sobre el IMC de la adolescente fueron la actividad física y el IMC de la madre, independientemente de la ingestión energética total y de la composición de la dieta.

Índice de masa corporal materno pre-embarazo y riesgo de malformaciones congénitas específicas: evidencia de una relación dosis-respuesta

OpenAIRE

Fuenzalida C,Javiera; Vera P-G,Claudio; Carvajal C,Jorge

2013-01-01

Antecedentes: Este estudio investiga la relación entre el índice de masa corporal (IMC) previo al embarazo y 26 malformaciones al nacer identificadas en el Registro de Defectos de Nacimientos de Florida. Métodos: El IMC (kg/m2) previo al embarazo se categorizó en bajo peso (

The Effectiveness of Al-Si Coatings for Preventing Interfacial Reaction in Al-Mg Dissimilar Metal Welding

Science.gov (United States)

Wang, Yin; Al-Zubaidy, Basem; Prangnell, Philip B.

2018-01-01

The dissimilar welding of aluminum to magnesium is challenging because of the rapid formation of brittle intermetallic compounds (IMC) at the weld interface. An Al-Si coating interlayer was selected to address this problem, based on thermodynamic calculations which predicted that silicon would change the reaction path to avoid formation of the normally observed binary Al-Mg IMC phases ( β-Al3Mg2 and γ-Al12Mg17). Long-term static heat treatments confirmed that a Si-rich coating will preferentially produce the Mg2Si phase in competition with the less stable, β-Al3Mg2 and γ-Al12Mg17 binary IMC phases, and this reduced the overall reaction layer thickness. However, when an Al-Si clad sheet was tested in a real welding scenario, using the Refill™ friction stir spot welding (FSSW) technique, Mg2Si was only produced in very small amounts owing to the much shorter reaction time. Surprisingly, the coating still led to a significant reduction in the IMC reaction layer thickness and the welds exhibited enhanced mechanical performance, with improved strength and fracture energy. This beneficial behavior has been attributed to the softer coating material both reducing the welding temperature and giving rise to the incorporation of Si particles into the reaction layer, which toughened the brittle interfacial IMC phases during crack propagation.

Fundamental and clinical evaluation of Fourier analysis for the detection of regional wall contraction abnormalities in the patients with myocardial infarction

International Nuclear Information System (INIS)

Murata, H.; Toyama, H.; Tabuchi, H.; Muraki, T.; Ohtake, E.; Chiba, K.; Yamada, H.

1982-01-01

The purpose of the present study are to evaluate fundamentally the method of Fourier analysis and to detect regional wall motion abnormality of the infarcted lesions by Fourier analysis. Fourier analyses were performed using the data obtained by first pass method in right anterior oblique projection (RAO) and by equilibrium method in left anterior oblique projection (LAO), and amplitude and phase were calculated. Amplitude and phase values needed to be corrected by R-R interval. On the detection of myocardial infarction, Fourier analyses in RAO and in LAO had same value for anterior infarctions. The analysis in RAO was more sensitive to detect infero-posterior lesions. On the other hand, the analysis in LAO was more sensitive for septal and lateral lesions

Ethical Issues in Using Children's Blood Lead Levels as a Remedial Action Objective

Science.gov (United States)

Evans, Emily Lorraine

2011-01-01

The Environmental Protection Agency measures the success or failure of Superfund site remediation efforts against remedial action objectives (RAOs). RAOs are frequently based on environmental contaminant concentrations, but with lead exposure, blood lead levels from the population at risk are often used. Although childhood lead screening is an important public health tool, an RAO based on child blood lead levels raises ethical concerns: public health efforts that are more reactive than preventive, a blood lead standard (10 μg/dL) that may not be fully protective, the use of a measure whose validity and reliability may be easily compromised, and exacerbation of environmental injustice and systematic disadvantages. The example of Bunker Hill mine, Kellogg, Idaho, allowed an examination of these ethical concerns. PMID:21836120

Comparison of self-perceived weight and desired weight versus actual body mass index among adolescents in Jamaica Comparación del peso autopercibido y el peso deseado frente al índice de masa corporal real en adolescentes de Jamaica

Directory of Open Access Journals (Sweden)

Sheila C. Barrett

2011-04-01

Full Text Available OBJECTIVE: To compare self-perceived body size, desired body size, and actual body mass index (BMI among adolescents in Jamaica, and to discuss the implications of these perceptions for chronic disease prevention. METHODS: A total of 276 Jamaican adolescents 14-19 years of age, randomly selected from grades 9-12 at 10 high schools participated in the study, which was conducted in October 2007. The perceived and desired BMI were measured using a silhouette of body figures representing nine BMI categories for males and females; these were compared to participants' actual BMI. RESULTS: Mean age was 15.6 ± 1.2 years. Actual BMI values classified 24.6% of the participants as underweight; 39.9% as normal; 14.5% as overweight; and 21% as obese. There were significant differences between participants' actual and perceived BMI (P 0.05. CONCLUSIONS: Females had higher actual BMI and lower perceived BMI than males. Jamaican adolescents, irrespective of ethnicity, age, place of residence, and socioeconomic status, had similar BMI. Interventions are needed to improve knowledge of a healthy body weight and the relationships among body weight, lifestyle choices, and the implications of excess body weight on chronic diseases.OBJETIVO: Comparar el tamaño corporal autopercibido, el tamaño corporal deseado y el índice de masa corporal real (IMC en adolescentes de Jamaica y analizar las implicaciones de dichas percepciones en la prevención de las enfermedades crónicas. MÉTODOS: El estudio se realizó en octubre del 2007 y participaron 276 adolescentes jamaiquinos de 14 a 19 años de edad, seleccionados aleatoriamente entre los grados 9 y 12 de 10 escuelas secundarias. Se midió el IMC percibido y el deseado usando figuras con una silueta corporal que representaban nueve categorías del IMC para hombres y mujeres, y se compararon con el IMC real de los participantes. RESULTADOS: La media de la edad fue de 15,6 ± 1,2 años. De acuerdo con los valores reales

An Examination of Integrated Marketing Communication in US Public Institutions of Higher Education

Science.gov (United States)

Edmiston, Dawn

2008-01-01

This research analyzes the strategic process of integrated marketing communication (IMC) and its current application in US public institutions of higher education (IHEs). The basis for this research was a survey questionnaire that analyzed the impact of IMC on 42 leading US public colleges and universities (as ranked by "U.S. News & World…

Indicadores antropométricos de la niñez en situación de calle en Medellín, Colombia

Directory of Open Access Journals (Sweden)

Camilo Noreña Herrera

2015-02-01

Full Text Available Objetivo: describir los indicadores antropométricos de Índice de Masa Corporal para la Edad (imc/e y Talla para la Edad (t/e de niños, niñas y adolescentes (nna en situación de calle (sc de Medellín, según características sociodemográficas y de consumo de drogas. Metodología: estudio descriptivo de 453 historiales de atención médica y nutricional de nna en sc. Los indicadores antropométricos se categorizaron de acuerdo a los patrones de crecimiento aceptados para Colombia. Se realizó un análisis descriptivo bivariado entre indicadores antropométricos y variables sociodemográficas y de consumo de drogas. Resultados: el 27,8% de los nna tenía talla baja y el 35,3%, riesgo de talla baja. La talla baja fue mayor en hombres (89,7% que en mujeres (10,3% (p < 0,05. Con respecto al imc/e, el 4,2% presentó delgadez, el 14,1% riesgo de delgadez y, un 2,2% presentó exceso de peso. Se encontró diferencia estadísticamente significativa (p < 0,01 entre el imc/e y la edad y entre t/e y el sexo y el nivel de escolaridad. Conclusiones: los nna en sc presentan indicadores antropométricos que evidencian una desfavorable situación nutricional, especialmente para los adolescentes del sexo masculino. Es necesario, además de políticas y programas orientados a la recuperación nutricional de la población, abordar los determinantes estructurales que ocasionan la pobreza, la inequidad y la inseguridad alimentaria en la ciudad para prevenir la situación de vida en calle de NNA.

Correlación de variables antropométricas como predictor de salud, en una población de niños y adolescentes con síndrome de Down de Temuco, Chile

Directory of Open Access Journals (Sweden)

Mauricio Cresp Barria

2014-04-01

Full Text Available Antecedentes. En los últimos años se ha evidenciado la importancia de investigar sobre la obesidad, incluyendo a grupos de sujetos que presentan necesidades educativas especiales permanentes, como es el caso del Síndrome de Down. Objetivo. Determinar la correlación entre el Índice de Masa Corporal (IMC con la circunferencia de cintura (CCi y el IMC con la circunferencia de cadera (CCa de los niños y adolescentes con síndrome de Down. Materiales y métodos. Se realizó un estudio de corte transversal, donde se evaluaron 42 niños y adolescentes, 23 hombres (54,7% y 19 mujeres (35,3%, entre 3 y 16 años de edad, alumnos de escuelas especiales de Temuco, Chile. Para obtener el IMC y la CCa se utilizó el método descrito por la OMS. Resultados. Se evidencia un alto grado de correlación entre IMC y CCi (0,776 y entre IMC y CCa (0,771. Además el 61,9% del total presentan sobrepeso u obesidad. El 52,1% de los hombres y el 73,6% de las mujeres presentan obesidad o sobrepeso. Discusión. A partir de los resultados, es recomendable la utilización de la circunferencia de cintura y cadera, además del IMC para la detección temprana de problemas asociados a la obesidad. Además de focalizar el trabajo a realizar con esta población especial, generando estrategias que involucren a distintos profesionales del ámbito de la salud y del ejercicio físico, permitiendo abordar sistémicamente desde los primeros años la prevención de la obesidad y las patologías asociadas.

Control of a deareador level of a thermoelectric power station using modern control techniques; Control de nivel de un deareador de una central termoelectrica utilizando tecnicas de control moderno

Energy Technology Data Exchange (ETDEWEB)

Chavez Estrada, Jose Israel

1997-01-01

The present work shows the implementation of the scheme of predictive control IMC (Internal Model Control) in order to control the level of the deareador of a combined cycle thermoelectric power station of (C.C.T.S.). The implementation has the purpose of looking for alternative strategies of control to the classic ones (PID`s) that more efficiently control the variables of interest, in addition to getting into the new control techniques of control. Following the philosophy of predictive control IMC the form to applying this technique is shown, as well as the implementation of this type of controllers. A comparison of predictive control IMC is made with the scheme of conventional control (three control elements PID`s ) used at present to control the level of the deareador in the Combined Cycle Thermoelectric Power stations of Dos Bocas, Veracruz, Mexico and of Gomez Palacio, Durango, Mexico. [Espanol] El presente trabajo muestra la implementacion del esquema de control predictivo IMC (Control con Modelo Interno) con el objeto de controlar el nivel del deareador de una Central Termoelectrica de Ciclo Combinado (C.T.C.C.). La implementacion tiene la finalidad de buscar estrategias de control alternas a las clasicas (PID`s) que controlen mas eficientemente la variable de interes, ademas de incursionar en las nuevas tecnicas de control. Siguiendo la filosofia del control predictivo IMC se muestra la forma de aplicar esta tecnica, asi como la implementacion de este tipo de controladores. Se hace una comparacion del control predictivo IMC con el esquema de control convencional (control de tres elementos PID`s) utilizando actualmente para controlar el nivel del deareador en las centrales termoelectricas de ciclo combinado de Dos Bocas, Veracruz y de Gomez Palacio, Durango en Mexico.

Intestinal and peritoneal mast cells differ in kinetics of quantal release

Energy Technology Data Exchange (ETDEWEB)

Balseiro-Gomez, Santiago, E-mail: sanbalgom@alum.us.es; Ramirez-Ponce, M. Pilar, E-mail: pponce@us.es; Acosta, Jorge, E-mail: jorgealo@us.es; Ales, Eva, E-mail: eales@us.es; Flores, Juan A., E-mail: jaflores@us.es

2016-01-15

5-hydroxytriptamine (5-HT, serotonin) storage and release in mast cell (MC) secretory granules (SG) are dependent on serglycin proteoglycans (PG). This notion is based on the studies of MC of the connective tissue subtype that predominantly contain PG of the heparin type, whereas intestinal mucosal MC, which contain predominantly chondroitin sulfate, have been poorly explored. In the present study, we addressed the possibility that PG contents may differently affect the storage and release of preformed mediators in these two MC subclasses and explain in part their different functional properties. Rat peritoneal (PMC) and intestinal mast cells (IMC) were isolated and purified using a percoll gradient, and the efflux of 5-HT from each SG was measured by amperometric detection. IMC exhibited a ∼34% reduction in the release of 5-HT compared with PMC because of a lower number of exocytotic events, rather than a lower secretion per single exocytotic event. Amperometric spikes from IMC exhibited a slower decay phase and increased half-width but a similar ascending phase and foot parameters, indicating that the fusion pore kinetics are comparable in both MC subclasses. We conclude that both PG subtypes are equally efficient systems, directly involved in serotonin accumulation, and play a crucial role in regulating the kinetics of exocytosis from SG, providing specific secretory properties for the two cellular subtypes. - Highlights: • We improved a method for isolating and purifying IMC. • There was a reduction in total serotonin release in IMC with respect to PMC. • This decrease was not due to less secretion per quantum but a lower number of exocytotic events. • There was also a deceleration of exocytosis in IMC with respect to PMC.

Effect of process parameters on mechanical properties of friction stir spot welded magnesium to aluminum alloys

International Nuclear Information System (INIS)

Rao, H.M.; Yuan, W.; Badarinarayan, H.

2015-01-01

Highlights: • Lap-shear failure load of ∼2.5 kN was achieved in dissimilar Mg to Al spot welds. • Failure load depends on both welding geometrical features and IMCs formation. • Thin and discontinuous IMCs formed in stir zone are beneficial for weld strength. • Low heat input and good material mixing/interlocking is essential for high strength. - Abstract: Friction stir spot welding was applied to dissimilar cast magnesium (Mg) alloy AM60B and wrought aluminum (Al) alloy 6022-T4 under various welding conditions. The influence of tool rotation rate and shoulder plunge depth on lap-shear failure load was examined. Welds were made at four different tool rotation rates of 1000, 1500, 2000 and 2500 revolution per minute (rpm) and various tool shoulder plunge depths from 0 mm to 0.9 mm. The cross section of each weld exhibited the formation of intermetallic compounds (IMCs) in the stir zone. An increase in tool rotation rate decreased the width of the stir zone and resulted in lower lap-shear failure loads. The stir zone width increased and interlocking of IMCs was observed with an increase in tool shoulder plunge depth at 1000 rpm. High lap-shear failure loads were achieved in welds having a large stir zone width with formation of discontinuous IMCs at the tip of the interfacial hook. An average lap-shear failure load of 2.5 kN was achieved for welds made at 1000 rpm and 0.9 mm shoulder plunge. The present study suggests that the mechanical properties of friction stir spot welded dissimilar alloys are greatly influenced by the stir zone width, interfacial hooks and IMCs which are all weld process dependent

Homogeneous (Cu, Ni)6Sn5 intermetallic compound joints rapidly formed in asymmetrical Ni/Sn/Cu system using ultrasound-induced transient liquid phase soldering process.

Science.gov (United States)

Li, Z L; Dong, H J; Song, X G; Zhao, H Y; Tian, H; Liu, J H; Feng, J C; Yan, J C

2018-04-01

Homogeneous (Cu, Ni) 6 Sn 5 intermetallic compound (IMC) joints were rapidly formed in asymmetrical Ni/Sn/Cu system by an ultrasound-induced transient liquid phase (TLP) soldering process. In the traditional TLP soldering process, the intermetallic joints formed in Ni/Sn/Cu system consisted of major (Cu, Ni) 6 Sn 5 and minor Cu 3 Sn IMCs, and the grain morphology of (Cu, Ni) 6 Sn 5 IMCs subsequently exhibited fine rounded, needlelike and coarse rounded shapes from the Ni side to the Cu side, which was highly in accordance with the Ni concentration gradient across the joints. However, in the ultrasound-induced TLP soldering process, the intermetallic joints formed in Ni/Sn/Cu system only consisted of the (Cu, Ni) 6 Sn 5 IMCs which exhibited an uniform grain morphology of rounded shape with a remarkably narrowed Ni concentration gradient. The ultrasound-induced homogeneous intermetallic joints exhibited higher shear strength (61.6 MPa) than the traditional heterogeneous intermetallic joints (49.8 MPa). Copyright © 2017 Elsevier B.V. All rights reserved.

Electromigration-induced back stress in critical solder length for three-dimensional integrated circuits

Energy Technology Data Exchange (ETDEWEB)

Huang, Y. T.; Hsu, H. H.; Wu, Albert T., E-mail: atwu@ncu.edu.tw [Department of Chemical and Materials Engineering, National Central University, Jhongli City 320, Taiwan (China)

2014-01-21

Because of the miniaturization of electronic devices, the reliability of electromigration has become a major concern when shrinking the solder dimensions in flip-chip joints. Fast reaction between solders and electrodes causes intermetallic compounds (IMCs) to form, which grow rapidly and occupy entire joints when solder volumes decrease. In this study, U-grooves were fabricated on Si chips as test vehicles. An electrode-solder-electrode sandwich structure was fabricated by using lithography and electroplating. Gaps exhibiting well-defined dimensions were filled with Sn3.5Ag solders. The gaps between the copper electrodes in the test sample were limited to less than 15 μm to simulate microbumps. The samples were stressed at various current densities at 100 °C, 125 °C, and 150 °C. The morphological changes of the IMCs were observed, and the dimensions of the IMCs were measured to determine the kinetic growth of IMCs. Therefore, this study focused on the influence of back stress caused by microstructural evolution in microbumps.

Solid state synthesis, structural, physicochemical and optical properties of an inter-molecular compound: 2-hydroxy-1, 2-diphenylethanone-4-nitro-o-phenylenediamine system

Science.gov (United States)

Rai, U. S.; Singh, Manjeet; Rai, R. N.

2017-09-01

The phase diagram of 2-hydroxy-1, 2-diphenylethanone (HDPE)-4-nitro-o-phenylenediamine (NOPDA) system, determined by the thaw-melt method, gives two eutectics E1 (m p = 66.0 °C) and E2 (m p = 155.0 °C) with 0.30 and 0.55 mol fractions of NOPDA, respectively, and an 1:1 inter-molecular compound (IMC) (m p 162.0 °C). This IMC was synthesized by adopting the green synthetic method of solid state reaction. While its formation and structure were confirmed by the X-ray diffraction and spectroscopic methods, the ORTEP view gives mode of crystal packing, C‒H…O, C‒H…N, π-π stacking and the inter-molecular hydrogen bonding in the compound. The single crystal of the IMC shows 53% transmission and emits significantly higher dual fluorescence, and the band gap was computed to be 3.04 eV. The values of solubility of the IMC, measured in the temperature range 304-322 K, satisfy the mole fraction (X) and temperature equation: Xeq= 5.1324 × 10-7 e 0.01356T.

Valorisation of waste ilmenite mud in the manufacture of sulphur polymer cement.

Science.gov (United States)

Contreras, Manuel; Gázquez, Manuel Jesús; García-Díaz, Irene; Alguacil, Francisco J; López, Félix A; Bolívar, Juan Pedro

2013-10-15

This paper reports the preparation of sulphur polymer cements (SPCs) incorporating waste ilmenite mud for use in concrete construction works. The ilmenite mud raw material and the mud-containing SPCs (IMC-SPCs) were characterised physico-chemically and radiologically. The optimal IMC-SPC mixture had a sulphur/mud ratio (w/w) of 1.05 (mud dose 20 wt%); this cement showed the greatest compressive strength (64 MPa) and the lowest water absorption coefficient (0.4 g cm(-2) at 28 days). Since ilmenite mud is enriched in natural radionuclides, such as radium isotopes (2.0·10(3) Bq kg(-1)(228)Ra and 5.0·10(2) Bq kg(-1)(226)Ra), the IMC-SPCs were subjected to leaching experiments, which showed their environmental impact to be negligible. The activity concentration indices for the different radionuclides in the IMC-SPCs containing 10% and 20% ilmenite mud met the demands of international standards for materials used in the construction of non-residential buildings. Copyright © 2013 Elsevier Ltd. All rights reserved.

Temperature Control of Heating Zone for Drying Process: Effect of Air Velocity Change

Directory of Open Access Journals (Sweden)

Wutthithanyawat Chananchai

2016-01-01

Full Text Available This paper proposes a temperature control technique to adjust air temperature in a heating zone for drying process. The controller design is achieved by using an internal model control (IMC approach. When the IMC controller parameters were designed by calculating from an actual process transfer function estimated through an open-loop step response with input step change from 50% to 60% at a reference condition at air velocity of 1.20 m/s, the performance of temperature controller was experimentally tested by varying an air velocity between 1.32 m/s and 1.57 m/s, respectively. The experimental results showed that IMC controller had a high competency for controlling the drying temperature.

Fundus autofluorescence in retinal artery occlusion: A more precise diagnosis.

Science.gov (United States)

Bacquet, J-L; Sarov-Rivière, M; Denier, C; Querques, G; Riou, B; Bonin, L; Barreau, E; Labetoulle, M; Rousseau, A

2017-10-01

Retinal artery occlusion (RAO) is a medical emergency associated with a high risk of cerebral vascular accident and other cardiovascular events. Among patients with non-arteritic RAO, a retinal embolus is observed in approximately 40% of cases. Fundus examination and retinography are not reliable to predict the nature of the emboli. We report three consecutive cases of central and branch RAO that were investigated with fundus autofluorescence, fluorescein angiography and color retinal photographs. All patients underwent complete neurological and cardiovascular workups, with brain imaging, cardiac Doppler ultrasound, carotid Dopplers and Holter ECG's, to determine the underlying mechanism of retinal embolism. In the three cases, aged 77.7±4 years (2 women and 1 man), fundus autofluorescence demonstrated hyperautofluorescent emboli. In two cases, it allowed visualization of emboli that were not detected with fundus examination or retinography. The cardiovascular work-up demonstrated atheromatous carotid or aortic plaques in all patients. In one case, it permitted the diagnosis of RAO. Two of the three cases were considered to be of atherosclerotic origin and one of undefined origin. Fundus autofluorescence may help to detect and characterize retinal emboli. Since lipofuscin, which is present in large quantity in atherosclerotic plaques, is the main fluorophore detected with fundus autofluorescence, this non-invasive and simple examination may give information about the underlying mechanism of retinal embolism, and thus impact the etiologic assessment of RAO. Additional studies are necessary to confirm this potential role of autofluorescence. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Recent results in the decoding of Algebraic geometry codes

DEFF Research Database (Denmark)

Høholdt, Tom; Jensen, Helge Elbrønd; Nielsen, Rasmus Refslund

1998-01-01

We analyse the known decoding algorithms for algebraic geometry codes in the case where the number of errors is [(dFR-1)/2]+1, where dFR is the Feng-Rao distance......We analyse the known decoding algorithms for algebraic geometry codes in the case where the number of errors is [(dFR-1)/2]+1, where dFR is the Feng-Rao distance...

Temperature hysteretic effect and its influence on colossal ...

Indian Academy of Sciences (India)

Financial support from IUC-DAEF, Mumbai, India is greatly appreciated. References. [1] G H Rao, J R Sun, J K Liang, W Y Zhou and X R Cheng, Appl. Phys. Lett. 69, 424 (1996). [2] J R Sun, G H Rao, J K Liang and W Y Zhou, Appl. Phys. Lett. 69, 3924 (1996). [3] J Baszynski, J Kovac, A Kowalczyk, J. Magn. Magn. Mater. 195 ...

The Shock and Vibration Digest. Volume 16, Number 12

Science.gov (United States)

1984-12-01

Rades, M. Beards, G.EF. Ibrahim, R.A. Ramamurti, V. Beltzer, A. gnaczak, J. Rao, D. K. *BenzlIey, S. E. lwatsubo, T. Rao, J.S. Bernard , J.E. Jennings...Baskar, S .................. 2733 Bernante, R .......... 2152, 2200 Bojarskl, N.N ......... 743, 1818 Bass, H.E ................... 713 Bernard , R.D...2004 Chung, A.W ................. 1077 Cornwell , R.E ............... 396 Dalmotas, D.J .............. 1966 Chung, H ................... 2400

Reference Aid Abbreviations in the Latin American Press

Science.gov (United States)

1977-08-30

Argentino de Investigacion y Ensayo de Materiales CADIN Camara de Industrias de Nicaragua CADSE Comision Asesora de los Delitos Socio...IMC Industria de Materiales para la Construccion Instituto Mexicano del Cafe IMCE Instituto Mexicano de Comercio Exterior IMCIC Instituto...Generations (Gua) Revolucionarias NMU NNUU Naciones Unidas NOA Nueva Organizacion Anticomunista NON Nuevo Orden Nacional NORMETAL Empresa

Erythrocyte deformation in ischemic acute tubular necrosis and amelioration by splenectomy in the dog.

Science.gov (United States)

Mandal, A K; Taylor, C A; Bell, R D; Hillman, N M; Jarnot, M D; Cunningham, J D; Phillips, L G

1991-11-01

Bilateral renal artery occlusion (RAO) for 120 minutes in dogs results in acute tubular necrosis (ATN) and peritubular capillary (PTC) congestion with rapidly deteriorating renal function. We have shown that prior splenectomy minimizes RAO-induced renal functional and histopathologic changes. The purpose of this study was to examine whether this renal protection is due to prevention of red blood cell echinocyte formation and resultant renal PTC congestion. Echinocytes (burr cells) are poorly deformable, impart high viscosity to the blood, and may hinder reperfusion by increasing resistance to renal capillary blood flow. Splenectomized (SPLX) or sham-SPLX dogs were treated with bilateral RAO for 120 minutes. After RAO, renal function and renal blood flow were monitored, and peripheral blood red blood cells were examined at 1 hour and at 24-hour intervals for 96 hours. Renal biopsies were taken 1 hour after RAO and the kidneys removed 96 hours after RAO. The RBCs and renal tissues were studied using scanning electron microscopy. Renal function was assessed by endogenous creatinine clearance. Sham-SPLX animals showed a marked and sustained decrease in creatinine clearance, consistently elevated serum creatinine levels and fractional excretion of sodium, and diffuse ATN and PTC congestion with echinocytes. These animals had a peak in circulating echinocytes 1 hour after RAO (p less than 0.05), which showed an excellent negative correlation with creatinine clearance (r = -0.999; p less than 0.001). On the contrary, SPLX animals had essentially no change in serum creatinine or fractional excretion of sodium, minimal tubular changes, no PTC congestion, and no rise in circulating echinocytes during the 96-hour observation. In vitro treatment of the postischemic red blood cells from sham animals with adenosine-inosine or fresh postischemic plasma from the SPLX animals showed almost complete reversal to discocytes (normal red blood cells), whereas in vitro treatment of

Eco information 9. Influence of operation of the plants Jadrova vyradovacia spolocnost, a.s., on the environment, locality of Bohunice, within September 2014

International Nuclear Information System (INIS)

2014-10-01

In this leaflet the results of monitoring of chemical gaseous and liquid effluents into the rivers Vah and Dudvah as well as of radiation monitoring of Bohunice V1 NPP, Interim Spent Fuel Storage (MSVP), Bohunice Radioactive Waste Processing Centre (VK808 - BSC), The Main Production Unit (VK 46A - HVB) and Bitumenation Lines (VK 46B - BL) are presented. The radioactive effluents into atmosphere within January - September 2014 (for NPP V1, MSVP, BSC, HVB and BL, respectively) were: 1.483 MBq (0.002 of AL) for V1, 0.087 MBq (0.029% of AL) for MSVP, 0.084 MBq (0.060% of AL) for BSC, 0.400 MBq (0.061% of AL) for HVB and 0.028 MBq (0.020% of AL) for BL of aero-soles. The radioactive effluents into atmosphere and hydrosphere within a September 2014 for NPP V1, MSVP, and VK 808 BSC, respectively, were: 0.258 MBq (V1), 0.007 MBq (VK MSVP), 0.018 MBq (VK 808 BSC), 0.005 MBq (VK 46A) and 0.002 MBq (VK 46B) of aero-soles into atmosphere; 1.169 MBq (V1 and MSVP) and 0.522 MBq (TSU RAO and NPP A1) of corrosive and fission products, and 0.002 GBq (V1 and MSVP) and 16.740 GBq (TSU RAO and NPP A1) of tritium into the Vah River and 0.000 GBq (V1 and MSVP) and 0.000 MBq (TSU RAO and NPP A1) of corrosive and fission products and 0.000 GBq of tritium (V1) and 0.000 GBq of tritium (TSU RAO and NPP A1) into the Dudvah River). For the period January - September 2014 these radioactive effluents into recipient of Vah River represent for corrosive and fission products 12.402 MBq (0.095% of AL for V1 and MSVP) and 5.010 MBq (0.042% of AL for TSU RAO and MSVP); and for tritium it is 8.382 GBq (0.419% of AL) for V1 and MSVP, and 98.415 GBq (0.984% of AL) for TSU RAO and NPP A1 (into the Vah River) and for corrosive and fission products 0.000 MBq (V1 and MSVP) and 0.000 MBq (TSU RAO and NPP A1) (0.0000 of AL) of tritium (into the Dudvah River). Chemical effluents are reported, too.

Eco information 1. Influence of operation of the plants Jadrova vyradovacia spolocnost, a.s., on the environment, locality of Bohunice, within January 2016

International Nuclear Information System (INIS)

2016-02-01

In this leaflet the results of monitoring of chemical gaseous and liquid effluents into the rivers Vah and Dudvah as well as of radiation monitoring of Bohunice V1 NPP, Interim Spent Fuel Storage (MSVP), Bohunice Radioactive Waste Processing Centre (VK808 - BSC), The Main Production Unit (VK 46A - HVB) and Bitumenation Lines (VK 46B - BL) are presented. The alpha radioactive effluents into atmosphere within January 2016 (for NPP V1, MSVP, BSC, HVB and BL, respectively) were: 0.051 MBq (0.0001 of AL) for V1, 0.006 MBq (0.002% of AL) for MSVP, 0.007 MBq (0.005% of AL) for BSC, 0.027 MBq (0.004% of AL) for HVB and 0.003 MBq (0.002% of AL) for BL of aero-soles. The radioactive effluents into atmosphere and hydrosphere within a January 2016 for NPP V1, MSVP, and VK 808 BSC, respectively, were: 0.051 MBq (V1), 0.006 MBq (VK MSVP), 0.007 MBq (VK 808 BSC), 0.027 MBq (VK 46A) and 0.003 MBq (VK 46B) of aero-soles into atmosphere; 0.192 MBq (V1 and MSVP) and 0.346 MBq (TSU RAO and NPP A1) of corrosive and fission products, and 0.001 GBq (V1 and MSVP) and 10.991 GBq (TSU RAO and NPP A1) of tritium into the Vah River and 0.000 GBq (V1 and MSVP) and 0.000 MBq (TSU RAO and NPP A1) of corrosive and fission products and 0.000 GBq of tritium (V1) and 0.000 GBq of tritium (TSU RAO and NPP A1) into the Dudvah River). For the period January - January 2016 these radioactive effluents into recipient of Vah River represent for corrosive and fission products 0.192 MBq (0.0015% of AL for V1 and MSVP) and 0.346 MBq (0.003% of AL for TSU RAO and MSVP); and for tritium it is 0.001 GBq (0.00003% of AL) for V1 and MSVP, and 10.991 GBq (0.110% of AL) for TSU RAO and NPP A1 (into the Vah River) and for corrosive and fission products 0.000 MBq (V1 and MSVP) and 0.000 MBq (TSU RAO and NPP A1) (0.0000 of AL) of tritium (into the Dudvah River). Chemical effluents are reported, too.

Eco information 4 Influence of operation of the plants Jadrova vyradovacia spolocnost, a.s., on the environment, locality of Bohunice, within April 2016

International Nuclear Information System (INIS)

2016-05-01

In this leaflet the results of monitoring of chemical gaseous and liquid effluents into the rivers Vah and Dudvah as well as of radiation monitoring of Bohunice V1 NPP, Interim Spent Fuel Storage (MSVP), Bohunice Radioactive Waste Processing Centre (VK808 - BSC), The Main Production Unit (VK 46A - HVB) and Bitumenation Lines (VK 46B - BL) are presented. The alpha radioactive effluents into atmosphere within January - April 2016 (for NPP V1, MSVP, BSC, HVB and BL, respectively) were: 0.141 MBq (0.0002 of AL) for V1, 0.027 MBq (0.006% of AL) for MSVP, 0.029 MBq (0.016% of AL) for BSC, 0.127 MBq (0.015% of AL) for HVB and 0.009 MBq (0.006% of AL) for BL of aero-soles. The radioactive effluents into atmosphere and hydrosphere within a April 2016 for NPP V1, MSVP, and VK 808 BSC, respectively, were: 0.017 MBq (V1), 0.008 MBq (VK MSVP), 0.006 MBq (VK 808 BSC), 0.029 MBq (VK 46A) and 0.003 MBq (VK 46B) of aero-soles into atmosphere; 0.880 MBq (V1 and MSVP) and 0.397 MBq (TSU RAO and NPP A1) of corrosive and fission products, and 0.315 GBq (V1 and MSVP) and 7.163 GBq (TSU RAO and NPP A1) of tritium into the Vah River and 0.000 GBq (V1 and MSVP) and 0.000 MBq (TSU RAO and NPP A1) of corrosive and fission products and 0.000 GBq of tritium (V1) and 0.000 GBq of tritium (TSU RAO and NPP A1) into the Dudvah River). For the period January - April 2016 these radioactive effluents into recipient of Vah River represent for corrosive and fission products 2.658 MBq (0.0204% of AL for V1 and MSVP) and 1.744 MBq (0.015% of AL for TSU RAO and MSVP); and for tritium it is 0.736 GBq (0.03679% of AL) for V1 and MSVP, and 31.833 GBq (0.318% of AL) for TSU RAO and NPP A1 (into the Vah River) and for corrosive and fission products 0.000 MBq (V1 and MSVP) and 0.000 MBq (TSU RAO and NPP A1) (0.0000 of AL) of tritium (into the Dudvah River). Chemical effluents are reported, too.

Eco information 2. Influence of operation of the plants Jadrova vyradovacia spolocnost, a.s., on the environment, locality of Bohunice, within February 2016

International Nuclear Information System (INIS)

2016-03-01

In this leaflet the results of monitoring of chemical gaseous and liquid effluents into the rivers Vah and Dudvah as well as of radiation monitoring of Bohunice V1 NPP, Interim Spent Fuel Storage (MSVP), Bohunice Radioactive Waste Processing Centre (VK808 - BSC), The Main Production Unit (VK 46A - HVB) and Bitumenation Lines (VK 46B - BL) are presented. The alpha radioactive effluents into atmosphere within January - February 2016 (for NPP V1, MSVP, BSC, HVB and BL, respectively) were: 0.100 MBq (0.001 of AL) for V1, 0.013 MBq (0.004% of AL) for MSVP, 0.017 MBq (0.012% of AL) for BSC, 0.048 MBq (0.007% of AL) for HVB and 0.005 MBq (0.003% of AL) for BL of aero-soles. The radioactive effluents into atmosphere and hydrosphere within a February 2016 for NPP V1, MSVP, and VK 808 BSC, respectively, were: 0.049 MBq (V1), 0.007 MBq (VK MSVP), 0.011 MBq (VK 808 BSC), 0.020 MBq (VK 46A) and 0.002 MBq (VK 46B) of aero-soles into atmosphere; 0.706 MBq (V1 and MSVP) and 0.738 MBq (TSU RAO and NPP A1) of corrosive and fission products, and 0.419 GBq (V1 and MSVP) and 7.479 GBq (TSU RAO and NPP A1) of tritium into the Vah River and 0.000 GBq (V1 and MSVP) and 0.000 MBq (TSU RAO and NPP A1) of corrosive and fission products and 0.000 GBq of tritium (V1) and 0.000 GBq of tritium (TSU RAO and NPP A1) into the Dudvah River). For the period January - February 2016 these radioactive effluents into recipient of Vah River represent for corrosive and fission products 0.898 MBq (0.0069% of AL for V1 and MSVP) and 1.084 MBq (0.009% of AL for TSU RAO and MSVP); and for tritium it is 0.420 GBq (0.02098% of AL) for V1 and MSVP, and 18.470 GBq (0.185% of AL) for TSU RAO and NPP A1 (into the Vah River) and for corrosive and fission products 0.000 MBq (V1 and MSVP) and 0.000 MBq (TSU RAO and NPP A1) (0.0000 of AL) of tritium (into the Dudvah River). Chemical effluents are reported, too.

Thermal stress effects in intermetallic matrix composites

Science.gov (United States)

Wright, P. K.; Sensmeier, M. D.; Kupperman, D. S.; Wadley, H. N. G.

1993-01-01

Intermetallic matrix composites develop residual stresses from the large thermal expansion mismatch (delta-alpha) between the fibers and matrix. This work was undertaken to: establish improved techniques to measure these thermal stresses in IMC's; determine residual stresses in a variety of IMC systems by experiments and modeling; and, determine the effect of residual stresses on selected mechanical properties of an IMC. X ray diffraction (XRD), neutron diffraction (ND), synchrotron XRD (SXRD), and ultrasonics (US) techniques for measuring thermal stresses in IMC were examined and ND was selected as the most promising technique. ND was demonstrated on a variety of IMC systems encompassing Ti- and Ni-base matrices, SiC, W, and Al2O3 fibers, and different fiber fractions (Vf). Experimental results on these systems agreed with predictions of a concentric cylinder model. In SiC/Ti-base systems, little yielding was found and stresses were controlled primarily by delta-alpha and Vf. In Ni-base matrix systems, yield strength of the matrix and Vf controlled stress levels. The longitudinal residual stresses in SCS-6/Ti-24Al-llNb composite were modified by thermomechanical processing. Increasing residual stress decreased ultimate tensile strength in agreement with model predictions. Fiber pushout strength showed an unexpected inverse correlation with residual stress. In-plane shear yield strength showed no dependence on residual stress. Higher levels of residual tension led to higher fatigue crack growth rates, as suggested by matrix mean stress effects.

Influence of Difference Solders Volume on Intermetallic Growth of Sn-4.0Ag-0.5Cu/ENEPIG

Directory of Open Access Journals (Sweden)

Saliza Azlina O.

2016-01-01

Full Text Available In recent years, portable electronic packaging products such as smart phones, tablets, notebooks and other gadgets have been developed with reduced size of component packaging, light weight, high speed and with enhanced performance. Thus, flip chip technology with smaller solder sphere sizes that would produce fine solder joint interconnections have become essential in order to fulfill these miniaturization requirements. This study investigates the interfacial reactions and intermetallics formation during reflow soldering and isothermal aging between Sn-4.0Ag-0.5Cu (SAC405 and electroless nickel/immersion palladium/immersion gold (EN(PEPIG. Solder diameters of 300 μm and 700 μm were used to compare the effect of solder volume on the solder joint microstructure. The solid state isothermal aging was performed at 125°C starting from 250 hours until 2000 hours. The results revealed that only (Cu,Ni6Sn5 IMC was found at the interface during reflow soldering while both (Cu,Ni6Sn5 and (Ni,Cu3Sn4 IMC have been observed after aging process. Smaller solder sizes produced thinner IMC than larger solder joints investigated after reflow soldering, whereas the larger solders produced thinner IMC than the smaller solders after isothermal aging. Aging duration of solder joints has been found to be increase the IMC’s thickness and changed the IMC morphologies to spherical-shaped, compacted and larger grain size.

Molecular population dynamics of DNA structures in a bcl-2 promoter sequence is regulated by small molecules and the transcription factor hnRNP LL.

Science.gov (United States)

Cui, Yunxi; Koirala, Deepak; Kang, HyunJin; Dhakal, Soma; Yangyuoru, Philip; Hurley, Laurence H; Mao, Hanbin

2014-05-01

Minute difference in free energy change of unfolding among structures in an oligonucleotide sequence can lead to a complex population equilibrium, which is rather challenging for ensemble techniques to decipher. Herein, we introduce a new method, molecular population dynamics (MPD), to describe the intricate equilibrium among non-B deoxyribonucleic acid (DNA) structures. Using mechanical unfolding in laser tweezers, we identified six DNA species in a cytosine (C)-rich bcl-2 promoter sequence. Population patterns of these species with and without a small molecule (IMC-76 or IMC-48) or the transcription factor hnRNP LL are compared to reveal the MPD of different species. With a pattern recognition algorithm, we found that IMC-48 and hnRNP LL share 80% similarity in stabilizing i-motifs with 60 s incubation. In contrast, IMC-76 demonstrates an opposite behavior, preferring flexible DNA hairpins. With 120-180 s incubation, IMC-48 and hnRNP LL destabilize i-motifs, which has been previously proposed to activate bcl-2 transcriptions. These results provide strong support, from the population equilibrium perspective, that small molecules and hnRNP LL can modulate bcl-2 transcription through interaction with i-motifs. The excellent agreement with biochemical results firmly validates the MPD analyses, which, we expect, can be widely applicable to investigate complex equilibrium of biomacromolecules. © 2014 The Author(s). Published by Oxford University Press [on behalf of Nucleic Acids Research].

Fully in Silico Calibration of Empirical Predictive Models for Environmental Fate Properties of Novel Munitions Compounds

Science.gov (United States)

2016-04-01

constants using several IMC related aromatic amines. To develop QSARs with these data, many possible descriptors were evaluated , ranging from simple to...converted to approximate half-lives to give. The blue symbols are experimental data, obtained with IMC related amino compounds...calibrated “in silico” that predict the hydrolysis behavior of the diverse range of energetic NACs. However, new experimental and computational

Effects of top management involvement in integrated marketing communications

Directory of Open Access Journals (Sweden)

Nina Hočevar

2007-12-01

Full Text Available There is scarce empirical evidence in the academic literature of how top management involvement influences the degree of integrated marketing communications. At the same time, some authors believe that this relationship should be explored more extensively.In this paper we present one possible approach to investigating the relationship between top management involvement and the degree of integrated marketing communications. Our research established that a greater involvement of top management in marketing communications could be associated with a higher degree of IMC. Investigating the relationship between management and IMC is indeed at a very early stage. We suggest that this study has provided a basis for future research on the relationship between top management involvement in marketing communications and the degree of IMC.

Comparison of a priori versus provisional heparin therapy on radial artery occlusion after transradial coronary angiography and patent hemostasis (from the PHARAOH Study).

Science.gov (United States)

Pancholy, Samir B; Bertrand, Olivier F; Patel, Tejas

2012-07-15

Systemic anticoagulation decreases the risk of radial artery occlusion (RAO) after transradial catheterization and standard occlusive hemostasis. We compared the efficacy and safety of provisional heparin use only when the technique of patent hemostasis was not achievable to standard a priori heparin administration after radial sheath introduction. Patients referred for coronary angiography were randomized in 2 groups. In the a priori group, 200 patients received intravenous heparin (50 IU/kg) immediately after sheath insertion. In the provisional group, 200 patients did not receive heparin during the procedure. After sheath removal, hemostasis was obtained using a TR band (Terumo corporation, Tokyo, Japan) with a plethysmography-guided patent hemostasis technique. In the provisional group, no heparin was given if radial artery patency could be obtained and maintained. If radial patency was not achieved, a bolus of heparin (50 IU/kg) was given. Radial artery patency was evaluated at 24 hours (early RAO) and 30 days after the procedure (late RAO) by plethysmography. Patent hemostasis was obtained in 67% in the a priori group and 74% in the provisional group (p = 0.10). Incidence of RAO remained similar in the 2 groups at the early (7.5% vs 7.0%, p = 0.84) and late (4.5% vs 5.0%, p = 0.83) evaluations. Women, patients with diabetes, patients having not received heparin, and patients without radial artery patency during hemostasis had more RAO. By multivariate analysis, patent radial artery during hemostasis (odds ratio [OR] 0.03, 95% confidence interval [CI] 0.004 to 0.28, p = 0.002) and diabetes (OR 11, 95% CI 3 to 38,p patent hemostasis is maintained. Copyright © 2012 Elsevier Inc. All rights reserved.

Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey.

Science.gov (United States)

2017-03-01

The age of onset of rheumatoid arthritis (RA) is an important outcome predictor. Northern countries report an age of RA onset of around 50 years, but apparently, variability exists across different geographical regions. The objective of the present study is to assess whether the age of onset of RA varies across latitudes worldwide. In a proof-of-concept cross-sectional worldwide survey, rheumatologists from preselected cities interviewed 20 consecutive RA patients regarding the date of RA onset (RAO, when the patient first noted a swollen joint). Other studied variables included location of each city, rheumatologist settings, latitudes (10° increments, south to north), longitudes (three regions), intracountry consistency, and countries' Inequality-adjusted Human Development Index (IHDI). Data from 2481 patients (82% females) were obtained from 126 rheumatologists in 77 cities of 41 countries. Worldwide mean age of RAO was 44 ± 14 years (95% CI 44-45). In 28% of patients, RA began before age 36 years and before age 46 years in 50% of patients. RAO was 8 years earlier around the Tropic of Cancer when compared with northern latitudes (p worldwide. We postulate that countries' developmental status and their geographical and geomagnetic location influence the age of RAO.

The optimal project position for demonstrating tricuspid annulus in angiography: an experimental study

International Nuclear Information System (INIS)

Bai Yuan; Zong Gongjun; Wang Hongru; Qin Yongwen; Huang Xinmiao; Jiang Haibin

2009-01-01

Objective: To explore the optimal project position for demonstrating tricuspid annulus angiographically in experimental goats. Methods: Eight healthy goats underwent right atrial angiography by using 6 F pig tail catheters. Under fluoroscopic monitoring the contrast media (total 110 ml, flow rate 12 ml/ s, pressure 800 psi) was injected continuously while a serious exposures were performed from RAO position to LAO position (totally 180 degree rotation). The maximum diameter of the tricuspid annulus in every picture was measured and the results were compared with that obtained from sonography. Results: The procedure was successful in all 8 experimental goats. The optimal project position to display the tricuspid annulus was at 27 degree ± 3 degree in RAO position. Conclusion: In angiography, the tricuspid annulus can be best demonstrated at the project position of 27 degree ± 3 degree in RAO. (authors)

Influence of Zn Interlayer on Interfacial Microstructure and Mechanical Properties of TIG Lap-Welded Mg/Al Joints

Science.gov (United States)

Gao, Qiong; Wang, Kehong

2016-03-01

This study explored 6061 Al alloy and AZ31B Mg alloy joined by TIG lap welding with Zn foils of varying thicknesses, with the additional Zn element being imported into the fusion zone to alloy the weld seam. The microstructures and chemical composition in the fusion zone near the Mg substrate were examined by SEM and EDS, and tensile shear strength tests were conducted to investigate the mechanical properties of the Al/Mg joints, as well as the fracture surfaces, and phase compositions. The results revealed that the introduction of an appropriate amount of Zn transition layer improves the microstructure of Mg/Al joints and effectively reduces the formation of Mg-Al intermetallic compounds (IMCs). The most common IMCs in the fusion zone near the Mg substrate were Mg-Zn and Mg-Al-Zn IMCs. The type and distribution of IMCs generated in the weld zone differed according to Zn additions; Zn interlayer thickness of 0.4 mm improved the sample's mechanical properties considerably compared to thicknesses of less than 0.4 mm; however, any further increase in Zn interlayer thickness of above 0.4 mm caused mechanical properties to deteriorate.

A study on the effects of marketing communication using integrated marketing communication

Directory of Open Access Journals (Sweden)

Solmaz Sellahvarzi

2014-07-01

Full Text Available Integrated Marketing Communication (IMC is one of the needed concepts in competitive edge. IMC is defined as a cross functional process for creating and nourishing profitable relationships with customers and other stakeholders by strategically controlling or impacting all messages sent to these groups. It ensures that all forms of communications and messages are carefully linked together. This study investigates the effectiveness of marketing communication in an Iranian automaker named Khodro using IMC system. The study tries to audit the rate of marketing relationship integrity and its outcome on organization performance. The study designs a questionnaire and distributes it among 384 randomly selected people who use this firm’s services and Cronbach alpha has been calculated as 0.974. Hypotheses of this survey are exanimated by Pearson correlation test as well as pairwise t-student tests. The results show the effects of integrated marketing Communication on organization performance. In addition, there is a significant positive correlation relationship between integrated marketing communication with mission marketing, Cross functional Strategic Planning and Interactivity. Finally, there is a significant positive correlation relationship between dimensions of IMC.

KOMUNIKASI PEMASARAN PT PINDAD (PERSERO DI KAWASAN ASIA TENGGARA

Directory of Open Access Journals (Sweden)

Mochamad Yoesdinar Oktora

2017-12-01

Full Text Available Pemasaran yang dilakukan PT Pindad berkenaan dengan konsep konsep G to G dan menjadikan kepentingan publik serta isu keamanan negara sebagai nilai jualnya.. Oleh karena itu, penelitian ini bertujuan untuk dapat mendeskripsikan dan menganalisa Integrated Marketing Communication (IMC PT Pindad (Persero dalam memasarkan Alutsista di Kawasan Asia Tenggara. Penelitian ini berdasarkan paradigma postpositivisme, serta pendekatan kualitatif dengan metode studi kasus. Informan sebanyak 4 orang yang dipilih secara purposif. Teknik pengumpulan data melalui wawancara, observasi non partisipan dan studi literatur. Teknik analisis data melalui model interaktif dan Miles & Huberman, sedangkan teknik validasi data melalui triangulasi sumber. Hasil penelitian menunjukan bahwa IMC PT Pindad dilakukan melalui Acara dan pengalaman, Promosi penjualan, Hubungan masyarakat dan publisitas, Pemasaran langsung, Penjualan, dan Periklanan. Alasan PT Pindad menggunakan IMC utamanya karena penerapan konsep G to G yang mengedepankan lobi-lobi di tingkat pemerintah serta hubungan bilateral dapat mendukung seluruh kegiatan pemasarannya. Evaluasi IMC PT Pindad menghasilkan output berupa kegiatan pemasaran yang berkontribusi positif pada penjulan yakni kegiatan penjualan personal melalui lobi-lobi di kalangan pemerintah serta penempatan agen-agen representatif PT Pindad di berbagai negara perwakilan Asia Tenggara. Sedangkan kegiatan pemasaran yang kurang berkontribusi pada penjualan Alutsista yakni periklanan.

Electrical characteristics for Sn-Ag-Cu solder bump with Ti/Ni/Cu under-bump metallization after temperature cycling tests

Science.gov (United States)

Shih, T. I.; Lin, Y. C.; Duh, J. G.; Hsu, Tom

2006-10-01

Lead-free solder bumps have been widely used in current flip-chip technology (FCT) due to environmental issues. Solder joints after temperature cycling tests were employed to investigate the interfacial reaction between the Ti/Ni/Cu under-bump metallization and Sn-Ag-Cu solders. The interfacial morphology and quantitative analysis of the intermetallic compounds (IMCs) were obtained by electron probe microanalysis (EPMA) and field emission electron probe microanalysis (FE-EPMA). Various types of IMCs such as (Cu1-x,Agx)6Sn5, (Cu1-y,Agy)3Sn, and (Ag1-z,Cuz)3Sn were observed. In addition to conventional I-V measurements by a special sample preparation technique, a scanning electron microscope (SEM) internal probing system was introduced to evaluate the electrical characteristics in the IMCs after various test conditions. The electrical data would be correlated to microstructural evolution due to the interfacial reaction between the solder and under-bump metallurgy (UBM). This study demonstrated the successful employment of an internal nanoprobing approach, which would help further understanding of the electrical behavior within an IMC layer in the solder/UBM assembly.

Implementation of internal model based control and individual pitch control to reduce fatigue loads and tower vibrations in wind turbines

Science.gov (United States)

Mohammadi, Ebrahim; Fadaeinedjad, Roohollah; Moschopoulos, Gerry

2018-05-01

Vibration control and fatigue loads reduction are important issues in large-scale wind turbines. Identifying the vibration frequencies and tuning dampers and controllers at these frequencies are major concerns in many control methods. In this paper, an internal model control (IMC) method with an adaptive algorithm is implemented to first identify the vibration frequency of the wind turbine tower and then to cancel the vibration signal. Standard individual pitch control (IPC) is also implemented to compare the performance of the controllers in term of fatigue loads reduction. Finally, the performance of the system when both controllers are implemented together is evaluated. Simulation results demonstrate that using only IMC or IPC alone has advantages and can reduce fatigue loads on specific components. IMC can identify and suppress tower vibrations in both fore-aft and side-to-side directions, whereas, IPC can reduce fatigue loads on blades, shaft and yaw bearings. When both IMC and IPC are implemented together, the advantages of both controllers can be used. The aforementioned analysis and comparisons were not studied in literature and this study fills this gap. FAST, AreoDyn and Simulink are used to simulate the mechanical, aerodynamic and electrical aspects of wind turbine.

Performance Analysis of a Decoding Algorithm for Algebraic Geometry Codes

DEFF Research Database (Denmark)

Jensen, Helge Elbrønd; Nielsen, Rasmus Refslund; Høholdt, Tom

1998-01-01

We analyse the known decoding algorithms for algebraic geometry codes in the case where the number of errors is greater than or equal to [(dFR-1)/2]+1, where dFR is the Feng-Rao distance......We analyse the known decoding algorithms for algebraic geometry codes in the case where the number of errors is greater than or equal to [(dFR-1)/2]+1, where dFR is the Feng-Rao distance...

Radwaste Treatment Centre Jaslovske Bohunice

International Nuclear Information System (INIS)

2000-01-01

In this leaflet the Bohunice Radwaste Treatment Centre (BSC RAO) is presented. BSC RAO is designed to process and treat liquid and solid radwaste, arising from the NPP A-1 decommissioning, from NPPs V-1, V-2, and Mochovce operations, as well as institutional radwaste of diverse institutional (hospitals, research institutes) in the Slovak Republic. Transport, sorting, incineration, compacting, concentration and cementation of radwaste as well as monitoring of emission are described

Effect of solder bump size on interfacial reactions during soldering between Pb-free solder and Cu and Ni/ Pd/ Au surface finishes

International Nuclear Information System (INIS)

NorAkmal, F.; Ourdjini, A.; Azmah Hanim, M.A.; Siti Aisha, I.; Chin, Y.T.

2007-01-01

Flip chip technology provides the ultimate in high I/ O-density and count with superior electrical performance for interconnecting electronic components. Therefore, the study of the intermetallic compounds was conducted to investigate the effect of solder bumps sizes on several surface finishes which are copper and Electroless Nickel/ Electroless Palladium/ Immersion Gold (ENEPIG) which is widely used in electronics packaging as surface finish for flip-chip application nowadays. In this research, field emission scanning electron microscopy (FESEM) analysis was conducted to analyze the morphology and composition of intermetallic compounds (IMCs) formed at the interface between the solder and UBM. The IMCs between the SAC lead-free solder with Cu surface finish after reflow were mainly (Cu, Ni) 6 Sn 5 and Cu 6 Sn 5 . While the main IMCs formed between lead-free solder on ENEPIG surface finish are (Ni, Cu) 3 Sn 4 and Ni 3 Sn 4 . The results from FESEM with energy dispersive x-ray (EDX) have revealed that isothermal aging at 150 degree Celsius has caused the thickening and coarsening of IMCs as well as changing them into more spherical shape. The thickness of the intermetallic compounds in both finishes investigated was found to be higher in solders with smaller bump size. From the experimental results, it also appears that the growth rate of IMCs is higher when soldering on copper compared to ENEPIG finish. Besides that, the results also showed that the thickness of intermetallic compounds was found to be proportional to isothermal aging duration. (author)

Prior exposure to instructional manipulation checks does not attenuate survey context effects driven by satisficing or Gricean norms

OpenAIRE

Hauser, David J.; Sunderrajan, Aashna; Natarajan, Madhuri; Schwarz, Norbert

2016-01-01

"Instructional manipulation checks (IMCs) are frequently included in unsupervised online surveys and experiments to assess whether participants pay close attention to the questions. However, IMCs are more than mere measures of attention - they also change how participants approach subsequent tasks, increasing attention and systematic reasoning. We test whether these previously documented changes in information processing moderate the emergence of response effects in surveys by presenting an I...

Obesidad como Factor de Riesgo para Trastornos Metabólicos en Adolescentes Mexicanos, 2005

OpenAIRE

Marcos-Daccarett, Nydia J.; Núñez-Rocha, Georgina M.; Salinas- Martínez, Ana M.; Santos-Ayarzagoitia, Magaly; Decanini-Arcaute, Horacio

2007-01-01

Objetivo Determinar la prevalencia y estimar el riesgo de obesidad para dislipidemias e hiperinsulinemia en adolescentes. Asimismo, evaluar la asociación lineal de medidas antropométricas y lípidos con insulina. Material y Métodos Se realizó un estudio transversal comparativo entre adolescentes obesos (índice de masa corporal=IMC>percentil 95 para edad y sexo; n=120) y no obesos (IMC

Integrated marketing communications paradigm in digital environment: The five pillars of integration

OpenAIRE

Rakić Beba; Rakić Mira

2014-01-01

This paper is focused on the paradigm of integrated marketing communications (IMC) in digital environment. The integration is analysed through five aspects. First, integration in terms of media; it means that IMC are performed through the mix of traditional media (print - newspapers, magazines; radio; television; direct-response media - telephone, direct mail, catalogue marketing; billboards; other 'specific media': product - especially brand, packaging; price; place; people; process; physica...

Evaluation of antipathogenic activity and adherence properties of human Lactobacillus strains for vaginal formulations.

Science.gov (United States)

Verdenelli, M C; Coman, M M; Cecchini, C; Silvi, S; Orpianesi, C; Cresci, A

2014-05-01

To test different Lactobacillus strains for their antipathogenic activity towards Candida strains and their adhesion properties for the preparation of vaginal ovules and douches to be used in vaginal candidiasis prevention. Five strains of lactobacilli were tested for their antimicrobial potential against different clinically isolated Candida strains. They were also screened for their ability to produce hydrogen peroxide and to coaggregate with pathogens. Adhesion properties of the five different Lactobacillus strains to HeLa cells and the presence of arcA gene were also assessed. The in vitro experiments demonstrated that all the five Lactobacillus strains tested possessed inhibitory action against the Candida strains using the radial streak method, but the effect is strain dependent. The same situation arises with regard to the ability of coaggregation that is present in all the strains into different degrees. Only Lactobacillus rhamnosus IMC 501(®) and Lactobacillus paracasei IMC 502(®) were able to produce H2O2 and none of the strains possess arcA gene. The most adherent strains to HeLa cells were Lact. rhamnosus IMC 501(®), Lact. paracasei IMC 502(®) and also their combination SYNBIO(®). This latter was selected for the preparation of ovules and douches using different matrix. Witepsol(®) ovules have proved the best formulation in terms of probiotic viability. Lactobacillus rhamnosus IMC 501(®), Lact. paracasei IMC 502(®) and SYNBIO(®) were able to produce H2O2, to coaggregate and to exert antimicrobial activity against pathogenic Candida strains and to strongly adhere to HeLa cells. All these properties together with those technological make these strains good candidates for the realization of formulations suitable for vaginal health. To develop new vaginal formulations taking into account the impact of probiotic strains on pathogens as well as the technological properties of the strains to validate their effectiveness in human health. © 2014 The

A Dosimetric Comparison of Breast Radiotherapy Techniques to Treat Locoregional Lymph Nodes Including the Internal Mammary Chain.

Science.gov (United States)

Ranger, A; Dunlop, A; Hutchinson, K; Convery, H; Maclennan, M K; Chantler, H; Twyman, N; Rose, C; McQuaid, D; Amos, R A; Griffin, C; deSouza, N M; Donovan, E; Harris, E; Coles, C E; Kirby, A

2018-06-01

Radiotherapy target volumes in early breast cancer treatment increasingly include the internal mammary chain (IMC). In order to maximise survival benefits of IMC radiotherapy, doses to the heart and lung should be minimised. This dosimetry study compared the ability of three-dimensional conformal radiotherapy, arc therapy and proton beam therapy (PBT) techniques with and without breath-hold to achieve target volume constraints while minimising dose to organs at risk (OARs). In 14 patients' datasets, seven IMC radiotherapy techniques were compared: wide tangent (WT) three-dimensional conformal radiotherapy, volumetric-modulated arc therapy (VMAT) and PBT, each in voluntary deep inspiratory breath-hold (vDIBH) and free breathing (FB), and tomotherapy in FB only. Target volume coverage and OAR doses were measured for each technique. These were compared using a one-way ANOVA with all pairwise comparisons tested using Bonferroni's multiple comparisons test, with adjusted P-values ≤ 0.05 indicating statistical significance. One hundred per cent of WT(vDIBH), 43% of WT(FB), 100% of VMAT(vDIBH), 86% of VMAT(FB), 100% of tomotherapy FB and 100% of PBT plans in vDIBH and FB passed all mandatory constraints. However, coverage of the IMC with 90% of the prescribed dose was significantly better than all other techniques using VMAT(vDIBH), PBT(vDIBH) and PBT(FB) (mean IMC coverage ± 1 standard deviation = 96.0% ± 4.3, 99.8% ± 0.3 and 99.0% ± 0.2, respectively). The mean heart dose was significantly reduced in vDIBH compared with FB for both the WT (P FB). Simple WT radiotherapy delivered in vDIBH achieves satisfactory coverage of the IMC while meeting heart and lung dose constraints. However, where higher isodose coverage is required, VMAT(vDIBH) is the optimal photon technique. The lowest OAR doses are achieved by PBT, in which the use of vDIBH does not improve dose statistics. Crown Copyright © 2018. Published by Elsevier Ltd. All rights reserved.

Relación entre síntomas depresivos, Índice de Masa Corporal y autopercepción del peso en adolescentes escolares

Directory of Open Access Journals (Sweden)

Edwin Herazo

2013-01-01

Full Text Available Objetivo: Conocer la asociación entre síntomas depresivos, índice de masa corporal (IMC y autopercepción del peso corporal en adolescentes escolares de Bogotá, D.C. (Colombia. Materiales y métodos: Se realizó un estudio analítico transversal en el que participaron estudiantes de colegios públicos. Los síntomas depresivos se cuantificaron con la versión de 10 ítems de la escala de Zung para depresión; el IMC a partir de la toma de peso y talla; y la autopercepción de peso corporal mediante una pregunta con tres opciones de respuesta (0=bajo, normal=1 y alto=2. Se calculó el coeficiente de correlación de Spearman (rs para estimar las asociaciones. Se aceptaron como significativos valores de rs mayores de 0,300. Resultados: Participaron 321 estudiantes, con edades entre 12 y 18 años, media=14.6 años (DE=1,6; el 64,2 % fueron mujeres. Las puntuaciones para síntomas depresivos se encontraron entre 10 y 36, media=20,6 (DE=4,7, moda=21, mediana=21; los IMC se observaron entre 14,5 y 29,8, media=20,5 (DE=3,0; y la autopercepción del peso fue baja en 15,0 %, normal en 71,0 % y alta en 14,0 %. La correlación entre síntomas depresivos y autopercepción del peso fue rs=-0,019 (p=0,740; entre síntomas depresivos e IMC, rs=- 0,098 (p=0,079; y entre IMC y autopercepción de peso, rs=0,446 (p<0,001. Conclusiones: El IMC guarda una relación estadísticamente significativa con la auto- percepción del peso corporal; sin embargo, los síntomas depresivos son independientes de la autopercepción del peso corporal. Se necesitan más investigaciones con adolescentes escolares colombianos.

Decoupling control of a five-phase fault-tolerant permanent magnet motor by radial basis function neural network inverse

Science.gov (United States)

Chen, Qian; Liu, Guohai; Xu, Dezhi; Xu, Liang; Xu, Gaohong; Aamir, Nazir

2018-05-01

This paper proposes a new decoupled control for a five-phase in-wheel fault-tolerant permanent magnet (IW-FTPM) motor drive, in which radial basis function neural network inverse (RBF-NNI) and internal model control (IMC) are combined. The RBF-NNI system is introduced into original system to construct a pseudo-linear system, and IMC is used as a robust controller. Hence, the newly proposed control system incorporates the merits of the IMC and RBF-NNI methods. In order to verify the proposed strategy, an IW-FTPM motor drive is designed based on dSPACE real-time control platform. Then, the experimental results are offered to verify that the d-axis current and the rotor speed are successfully decoupled. Besides, the proposed motor drive exhibits strong robustness even under load torque disturbance.

Comment on ''Topologically Massive Gauge Theories''

International Nuclear Information System (INIS)

Bezerra de Mello, E.R.

1988-01-01

In a recent paper by R. Pisarski and S. Rao concerning topologically massive quantum Yang--Mills theory, the expression of the P-even part of the non-Abelian gauge field self-energy at one-loop order is shown to obey a consistency condition, which is not fulfilled by the formula originally presented by S. Deser, R. Jackiw, and S. Templeton. In this comment, I present a recalculation which agress with Pisarski and Rao. copyright 1988 Academic Press, Inc

A study on the effects of marketing communication using integrated marketing communication

OpenAIRE

Solmaz Sellahvarzi; Vahid Reza Mirabi; Mehdi Iran Nejad Parizi

2014-01-01

Integrated Marketing Communication (IMC) is one of the needed concepts in competitive edge. IMC is defined as a cross functional process for creating and nourishing profitable relationships with customers and other stakeholders by strategically controlling or impacting all messages sent to these groups. It ensures that all forms of communications and messages are carefully linked together. This study investigates the effectiveness of marketing communication in an Iranian automaker named Khodr...

Strategi Komunikasi Pemasaran Terpadu pada Suratkabar Malaysia (Studi Deskriptif Harian Sinar Harian Selangor)

OpenAIRE

Nasarruddin, Razie Bin; Hermawan, Anang

2011-01-01

Sinar Harian has new comer daily newspaper in Selangor, and positioned as an independent newspapers. So, this media use marketing communication concepts in order to accepted by communities in their audience in Malaysia. The whole factor are become from their integrated marketing communication strategy (IMC), that have five indicators included advertising, personal selling, direct marketing, public relations and sales promotions as a promotional mix. Besides IMC strategy, Sinar Harian also mak...

Can the sentinel lymph node technique affect decisions to offer internal mammary chain irradiation?

International Nuclear Information System (INIS)

Bourre, Jean-Cyril; Payan, Raoul; Collomb, Delphine; Gallazzini-Crepin, Celine; Calizzano, Alex; Desruet, Marie-Dominique; Pasquier, Dominique; Bolla, Michel; Fagret, Daniel; Vuillez, Jean-Philippe

2009-01-01

Identification of the sentinel lymph node (SLN) for small mammary tumours (cT1N0) sometimes leads to detection of internal mammary chain (IMC) drainage. This information is often ignored by physicians. The present study sought to determine the frequency with which an internal mammary SLN was identified by peritumoral injection of radioactive tracer, and then to determine the patients in whom identification of an internal mammary SLN could have an impact on the radiation treatment plan. Between March 2002 and March 2008, 622 SLN biopsies performed in a cohort of 608 patients were analysed. Technetium-labelled nanocolloids were administered via three peritumoral injections, completed by a deep prepectoral injection, with the entire procedure performed under echographic guidance. The SLN was identified in 607 of the 622 patients, including 174 (28.7%) in the IMC. A total of 161 successful internal mammary biopsies were performed. Of the 622 patients, 18 showed SLN involvement in the IMC. In 7 of these patients, only the internal mammary SLN was affected. Prophylactic irradiation of the IMC was indicated in 376 patients, but only in 18 (4.8%) of these patients was there effectively IMC involvement; internal mammary SLN biopsy failed in 7 patients (1.9%). SLN detection by peritumoral injection, combined with the systematic removal of the internal mammary SLN, enabled the involvement of this region to be found in a nonnegligible number of patients. Such information should make it possible to personalize treatment for patients with stage cT1 mammary cancer and thereby avoid needless internal mammary radiation therapy in a large number of patients (93.4% in our study). (orig.)

Multiphoton imaging of low grade, high grade intraepithelial neoplasia and intramucosal invasive cancer of esophagus

Science.gov (United States)

Xu, Jian; Jiang, Liwei; Kang, Deyong; Wu, Xuejing; Xu, Meifang; Zhuo, Shuangmu; Zhu, Xiaoqin; Lin, Jiangbo; Chen, Jianxin

2017-04-01

Esophageal squamous cell carcinoma (ESCC) is devastating because of its aggressive lymphatic spread and clinical course. It is believed to occur through low-grade intraepithelial neoplasia (LGIN), high-grade intraepithelial neoplasia (HGIN), and intramucosal invasive cancer (IMC) before transforming to submucosal cancer. In particular, these early lesions (LGIN, HGIN and IMC), which involve no lymph node nor distant metastasis, can be cured by endoscopic treatment. Therefore, early identification of these lesions is important so as to offer a curative endoscopic resection, thus slowing down the development of ESCC. In this work, spectral information and morphological features of the normal esophageal mucosa are first studied. Then, the morphological changes of LGIN, HGIN and IMC are described. Lastly, quantitative parameters are also extracted by calculating the nuclear-to-cytoplasmic ratio of epithelial cells and the pixel density of collagen in the lamina propria. These results show that multiphoton microscopy (MPM) has the ability to identify normal esophageal mucosa, LGIN, HGIN and IMC. With the development of multiphoton endoscope systems for in vivo imaging, combined with a laser ablation system, MPM has the potential to provide immediate pathologic diagnosis and curative treatment of ESCC before the transformation to submucosal cancer in the future.

Evaluation of Die-Attach Bonding Using High-Frequency Ultrasonic Energy for High-Temperature Application

Science.gov (United States)

Lee, Jong-Bum; Aw, Jie-Li; Rhee, Min-Woo

2014-09-01

Room-temperature die-attach bonding using ultrasonic energy was evaluated on Cu/In and Cu/Sn-3Ag metal stacks. The In and Sn-3Ag layers have much lower melting temperatures than the base material (Cu) and can be melted through the heat generated during ultrasonic bonding, forming intermetallic compounds (IMCs). Samples were bonded using different ultrasonic powers, bonding times, and forces and subsequently aged at 300°C for 500 h. After aging, die shear testing was performed and the fracture surfaces were inspected by scanning electron microscopy. Results showed that the shear strength of Cu/In joints reached an upper plateau after 100 h of thermal aging and remained stable with aging time, whereas that of the Cu/Sn-3Ag joints decreased with increasing aging time. η-Cu7In4 and (Cu,Au)11In9 IMCs were observed at the Cu/In joint, while Cu3Sn and (Ag,Cu)3Sn IMCs were found at the Cu/Sn-3Ag joint after reliability testing. As Cu-based IMCs have high melting temperatures, they are highly suitable for use in high-temperature electronics, but can be formed at room temperature using an ultrasonic approach.

Fatores associados à obesidade em adolescentes

Directory of Open Access Journals (Sweden)

Fonseca Vania de Matos

1998-01-01

Full Text Available INTRODUÇÃO: A obesidade na adolescência é um fator preditivo da obesidade no adulto. Assim, foram avaliados os fatores associados à obesidade e o uso do índice de massa morporal (IMC. MÉTODO: Foram avaliados 391 estudantes aferindo-se: consumo de alimentos, hábitos alimentares, características antropométricas dos pais e atividade física. O IMC foi a variável dependente utilizada na regressão linear multivariada. RESULTADOS: A prevalência de sobrepeso foi 23,9% para meninos e 7,2% para meninas. Fazer dieta para emagrecer foi 7 vezes mais freqüente entre meninas do que entre meninos com sobrepeso. Nos meninos, idade, uso de dieta, omissão de desjejum, horas de televisão/"vídeo-game" e obesidade familiar apresentaram associação positiva e significante com IMC. Nas meninas, associaram-se positivamente: uso de dieta, omissão de desjejum e obesidade familiar e negativamente idade da menarca. A correlação do IMC com medidas antropométricas foi maior que 0,7. CONCLUSÕES: Um padrão estético de magreza parece predominar entre meninas e elas o atingem com hábitos e consumo alimentar inadequados.

Microstructure and Tensile Behavior of Laser Arc Hybrid Welded Dissimilar Al and Ti Alloys

Directory of Open Access Journals (Sweden)

Ming Gao

2014-02-01

Full Text Available Fiber laser-cold metal transfer arc hybrid welding was developed to welding-braze dissimilar Al and Ti alloys in butt configuration. Microstructure, interface properties, tensile behavior, and their relationships were investigated in detail. The results show the cross-weld tensile strength of the joints is up to 213 MPa, 95.5% of same Al weld. The optimal range of heat input for accepted joints was obtained as 83–98 J·mm−1. Within this range, the joint is stronger than 200 MPa and fractures in weld metal, or else, it becomes weaker and fractures at the intermetallic compounds (IMCs layer. The IMCs layer of an accepted joint is usually thin and continuous, which is about 1μm-thick and only consists of TiAl2 due to fast solidification rate. However, the IMCs layer at the top corner of fusion zone/Ti substrate is easily thickened with increasing heat input. This thickened IMCs layer consists of a wide TiAl3 layer close to FZ and a thin TiAl2 layer close to Ti substrate. Furthermore, both bead shape formation and interface growth were discussed by laser-arc interaction and melt flow. Tensile behavior was summarized by interface properties.

A Review of Dissimilar Welding Techniques for Magnesium Alloys to Aluminum Alloys

Directory of Open Access Journals (Sweden)

Liming Liu

2014-05-01

Full Text Available Welding of dissimilar magnesium alloys and aluminum alloys is an important issue because of their increasing applications in industries. In this document, the research and progress of a variety of welding techniques for joining dissimilar Mg alloys and Al alloys are reviewed from different perspectives. Welding of dissimilar Mg and Al is challenging due to the formation of brittle intermetallic compound (IMC such as Mg17Al12 and Mg2Al3. In order to increase the joint strength, three main research approaches were used to eliminate or reduce the Mg-Al intermetallic reaction layer. First, solid state welding techniques which have a low welding temperature were used to reduce the IMCs. Second, IMC variety and distribution were controlled to avoid the degradation of the joining strength in fusion welding. Third, techniques which have relatively controllable reaction time and energy were used to eliminate the IMCs. Some important processing parameters and their effects on weld quality are discussed, and the microstructure and metallurgical reaction are described. Mechanical properties of welds such as hardness, tensile, shear and fatigue strength are discussed. The aim of the report is to review the recent progress in the welding of dissimilar Mg and Al to provide a basis for follow-up research.

A Review of Dissimilar Welding Techniques for Magnesium Alloys to Aluminum Alloys

Science.gov (United States)

Liu, Liming; Ren, Daxin; Liu, Fei

2014-01-01

Welding of dissimilar magnesium alloys and aluminum alloys is an important issue because of their increasing applications in industries. In this document, the research and progress of a variety of welding techniques for joining dissimilar Mg alloys and Al alloys are reviewed from different perspectives. Welding of dissimilar Mg and Al is challenging due to the formation of brittle intermetallic compound (IMC) such as Mg17Al12 and Mg2Al3. In order to increase the joint strength, three main research approaches were used to eliminate or reduce the Mg-Al intermetallic reaction layer. First, solid state welding techniques which have a low welding temperature were used to reduce the IMCs. Second, IMC variety and distribution were controlled to avoid the degradation of the joining strength in fusion welding. Third, techniques which have relatively controllable reaction time and energy were used to eliminate the IMCs. Some important processing parameters and their effects on weld quality are discussed, and the microstructure and metallurgical reaction are described. Mechanical properties of welds such as hardness, tensile, shear and fatigue strength are discussed. The aim of the report is to review the recent progress in the welding of dissimilar Mg and Al to provide a basis for follow-up research. PMID:28788646

Closed-loop step response for tuning PID-fractional-order-filter controllers.

Science.gov (United States)

Amoura, Karima; Mansouri, Rachid; Bettayeb, Maâmar; Al-Saggaf, Ubaid M

2016-09-01

Analytical methods are usually applied for tuning fractional controllers. The present paper proposes an empirical method for tuning a new type of fractional controller known as PID-Fractional-Order-Filter (FOF-PID). Indeed, the setpoint overshoot method, initially introduced by Shamsuzzoha and Skogestad, has been adapted for tuning FOF-PID controller. Based on simulations for a range of first order with time delay processes, correlations have been derived to obtain PID-FOF controller parameters similar to those obtained by the Internal Model Control (IMC) tuning rule. The setpoint overshoot method requires only one closed-loop step response experiment using a proportional controller (P-controller). To highlight the potential of this method, simulation results have been compared with those obtained with the IMC method as well as other pertinent techniques. Various case studies have also been considered. The comparison has revealed that the proposed tuning method performs as good as the IMC. Moreover, it might offer a number of advantages over the IMC tuning rule. For instance, the parameters of the fractional controller are directly obtained from the setpoint closed-loop response data without the need of any model of the plant to be controlled. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

Facile synthesis of functionalized ionic surfactant templated mesoporous silica for incorporation of poorly water-soluble drug.

Science.gov (United States)

Li, Jing; Xu, Lu; Yang, Baixue; Wang, Hongyu; Bao, Zhihong; Pan, Weisan; Li, Sanming

2015-08-15

The present paper reported amino group functionalized anionic surfactant templated mesoporous silica (Amino-AMS) for loading and release of poorly water-soluble drug indomethacin (IMC) and carboxyl group functionalized cationic surfactant templated mesoporous silica (Carboxyl-CMS) for loading and release of poorly water-soluble drug famotidine (FMT). Herein, Amino-AMS and Carboxyl-CMS were facilely synthesized using co-condensation method through two types of silane coupling agent. Amino-AMS was spherical nanoparticles, and Carboxyl-CMS was well-formed spherical nanosphere with a thin layer presented at the edge. Drug loading capacity was obviously enhanced when using Amino-AMS and Carboxyl-CMS as drug carriers due to the stronger hydrogen bonding force formed between surface modified carrier and drug. Amino-AMS and Carboxyl-CMS had the ability to transform crystalline state of loaded drug from crystalline phase to amorphous phase. Therefore, IMC loaded Amino-AMS presented obviously faster release than IMC because amorphous phase of IMC favored its dissolution. The application of asymmetric membrane capsule delayed FMT release significantly, and Carboxyl-CMS favored sustained release of FMT due to its long mesoporous channels and strong interaction formed between its carboxyl group and amino group of FMT. Copyright © 2015 Elsevier B.V. All rights reserved.

The role of situation assessment and flight experience in pilots' decisions to continue visual flight rules flight into adverse weather.

Science.gov (United States)

Wiegmann, Douglas A; Goh, Juliana; O'Hare, David

2002-01-01

Visual flight rules (VFR) flight into instrument meteorological conditions (IMC) is a major safety hazard in general aviation. In this study we examined pilots' decisions to continue or divert from a VFR flight into IMC during a dynamic simulation of a cross-country flight. Pilots encountered IMC either early or later into the flight, and the amount of time and distance pilots flew into the adverse weather prior to diverting was recorded. Results revealed that pilots who encountered the deteriorating weather earlier in the flight flew longer into the weather prior to diverting and had more optimistic estimates of weather conditions than did pilots who encountered the deteriorating weather later in the flight. Both the time and distance traveled into the weather prior to diverting were negatively correlated with pilots' previous flight experience. These findings suggest that VFR flight into IMC may be attributable, at least in part, to poor situation assessment and experience rather than to motivational judgment that induces risk-taking behavior as more time and effort are invested in a flight. Actual or potential applications of this research include the design of interventions that focus on improving weather evaluation skills in addition to addressing risk-taking attitudes.

Experimental demonstration of invisible electromagnetic impedance matching cylindrical transformation optics cloak shell

Science.gov (United States)

Chen, Mingji; Wang, Changxian; Cheng, Xiaodong; Gong, Congcheng; Song, Weili; Yuan, Xujin; Fang, Daining

2018-04-01

The realization of an ideal invisible cloak implementing transformation optics is still missing. An impedance matching concept is implanted into transformation optics cloak to generate an impedance matching cloak (IMC) shell. In this work, it is proved that impedance matching structure reduces the cloaking structure’s disturbance to a propagating electromagnetic field and improves its invisibility measured by scattering field intensity. Such a cylindrical IMC shell is designed, fabricated with proposed rounded rectangular split-ring-resonators (RR-SRRs), and experimental measurements show the total scattering field of a perfect electric conductor (PEC) cylinder surrounded by an IMC shell is improved greatly compared to the PEC cylinder showing electromagnetic wave front ripple suppression and a considerable scattering shrinking effect. IMC shell backward scattering field is suppressed down to 7.29%, compared to the previous value of 86.7% due to its impedance matching character, and overall scattering field intensity shrinking is down to 19.3% compared to the previously realized value of 56.4%. Sideward scattering field recorded in the experiment also has a remarkable improvement compared to the PEC cylinder. The impedance matching concept might enlighten the realization of an ideal cloak and other novel electromagnetic cloaking and shielding structures.

Intrinsic and extrinsic motivations in primary care: an explanatory study among French general practitioners.

Science.gov (United States)

Sicsic, Jonathan; Le Vaillant, Marc; Franc, Carine

2012-12-01

Like many other OECD nations, France has implemented a pay-for-performance (P4P) model in primary care. However, the benefits have been debated, particularly regarding the possibly undesirable effects of extrinsic motivation (EM) on intrinsic motivation (IM). To examine the relationship between French GPs' IM and EM based on an intrinsic motivation composite score (IMCS) developed for this purpose. If a negative relationship is found, P4P schemes could have side effects on GPs' IM that is a key determinant of quality of care. From data on 423 GPs practicing in a region of France, IM indicators are selected using a multiple correspondence analysis and aggregated from a multilevel model. Several doctors' characteristics have significant impacts on IMCS variability, especially group practice and salaried practice. Qualitative EM variables are negatively correlated with the IMCS: GPs who report not being satisfied with their income or feeling "often" constrained by patients' requests in terms of consultations length and office appointments obtain a lower mean IMCS than other GPs. Our results provide a cautionary message to regulators who should take into account the potential side effects of increasing EM through policies such as P4P. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Behavior of aluminum oxide, intermetallics and voids in Cu-Al wire bonds

International Nuclear Information System (INIS)

Xu, H.; Liu, C.; Silberschmidt, V.V.; Pramana, S.S.; White, T.J.; Chen, Z.; Acoff, V.L.

2011-01-01

Nanoscale interfacial evolution in Cu-Al wire bonds during isothermal annealing from 175 deg. C to 250 deg. C was investigated by high resolution transmission electron microscopy (HRTEM). The native aluminum oxide film (∼5 nm thick) of the Al pad migrates towards the Cu ball during annealing. The formation of intermetallic compounds (IMC) is controlled by Cu diffusion, where the kinetics obey a parabolic growth law until complete consumption of the Al pad. The activation energies to initiate crystallization of CuAl 2 and Cu 9 Al 4 are 60.66 kJ mol -1 and 75.61 kJ mol -1 , respectively. During IMC development, Cu 9 Al 4 emerges as a second layer and grows together with the initial CuAl 2 . When Al is completely consumed, CuAl 2 transforms to Cu 9 Al 4 , which is the terminal product. Unlike the excessive void growth in Au-Al bonds, only a few voids nucleate in Cu-Al bonds after long-term annealing at high temperatures (e.g., 250 o C for 25 h), and their diameters are usually in the range of tens of nanometers. This is due to the lower oxidation rate and volumetric shrinkage of Cu-Al IMC compared with Au-Al IMC.

Results of a survey regarding irradiation of internal mammary chain in patients with breast cancer: practice is culture driven rather than evidence based.

Science.gov (United States)

Taghian, Alphonse; Jagsi, Reshma; Makris, Andreas; Goldberg, Saveli; Ceilley, Elizabeth; Grignon, Laurent; Powell, Simon

2004-11-01

To examine the self-reported practice patterns of radiation oncologists in North America and Europe regarding radiotherapy to the internal mammary lymph node chain (IMC) in breast cancer patients. A survey questionnaire was sent in 2001 to physician members of the American Society for Therapeutic Radiology and Oncology and European Society for Therapeutic Radiology and Oncology regarding their management of breast cancer. Respondents were asked whether they would treat the IMC in several clinical scenarios. A total of 435 responses were obtained from European and 702 responses from North American radiation oncologists. Respondents were increasingly likely to report IMC irradiation in scenarios with greater axillary involvement. Responses varied widely among different European regions, the United States, and Canada (p variation in attitudes regarding treatment of the IMC. The international patterns of variation mirror the divergent conclusions of studies conducted in the different regions, indicating that physicians may rely preferentially on evidence from local studies when making difficult treatment decisions. These variations in self-reported practice patterns indicate the need for greater data in this area, particularly from international cooperative trials. The cultural predispositions documented in this study are important to recognize, because they may continue to affect physician attitudes and practices, even as greater evidence accumulates.

A Review of Dissimilar Welding Techniques for Magnesium Alloys to Aluminum Alloys.

Science.gov (United States)

Liu, Liming; Ren, Daxin; Liu, Fei

2014-05-08

Welding of dissimilar magnesium alloys and aluminum alloys is an important issue because of their increasing applications in industries. In this document, the research and progress of a variety of welding techniques for joining dissimilar Mg alloys and Al alloys are reviewed from different perspectives. Welding of dissimilar Mg and Al is challenging due to the formation of brittle intermetallic compound (IMC) such as Mg 17 Al 12 and Mg₂Al₃. In order to increase the joint strength, three main research approaches were used to eliminate or reduce the Mg-Al intermetallic reaction layer. First, solid state welding techniques which have a low welding temperature were used to reduce the IMCs. Second, IMC variety and distribution were controlled to avoid the degradation of the joining strength in fusion welding. Third, techniques which have relatively controllable reaction time and energy were used to eliminate the IMCs. Some important processing parameters and their effects on weld quality are discussed, and the microstructure and metallurgical reaction are described. Mechanical properties of welds such as hardness, tensile, shear and fatigue strength are discussed. The aim of the report is to review the recent progress in the welding of dissimilar Mg and Al to provide a basis for follow-up research.

Willingness to Use Microbicides Is Affected by the Importance of Product Characteristics, Use Parameters, and Protective Properties

Science.gov (United States)

Morrow, Kathleen M.; Fava, Joseph L.; Rosen, Rochelle K.; Vargas, Sara; Barroso, Candelaria; Christensen, Anna L.; Woodsong, Cynthia; Severy, Lawrence

2008-01-01

Background Along with efficacy, a microbicide’s acceptability will be integral to its impact on the pandemic. Understanding Product Characteristics that users find most acceptable and determining who will use which type of product are key to optimizing use effectiveness. Objectives To evaluate psychometrically the Important Microbicide Characteristics (IMC) instrument and examine its relationship to willingness to use microbicides. Results Exploratory and confirmatory factor analyses revealed 2 IMC subscales (Cronbach’s coefficient α: Product Characteristics subscale (α = 0.84) and Protective Properties subscale (α = 0.89)). Significant differences on Product Characteristics subscale scores were found for history of douching (P = 0.002) and employment status (P = 0.001). Whether a woman used a method to prevent pregnancy or sexually transmitted disease (STD) in the last 3 months (P IMC instrument serves as a template for future studies of candidate microbicides. PMID:17325607

Design of an Internal Model Control strategy for single-phase grid-connected PWM inverters and its performance analysis with a non-linear local load and weak grid.

Science.gov (United States)

Chaves, Eric N; Coelho, Ernane A A; Carvalho, Henrique T M; Freitas, Luiz C G; Júnior, João B V; Freitas, Luiz C

2016-09-01

This paper presents the design of a controller based on Internal Model Control (IMC) applied to a grid-connected single-phase PWM inverter. The mathematical modeling of the inverter and the LCL output filter, used to project the 1-DOF IMC controller, is presented and the decoupling of grid voltage by a Feedforward strategy is analyzed. A Proportional - Resonant Controller (P+Res) was used for the control of the same plant in the running of experimental results, thus moving towards the discussion of differences regarding IMC and P+Res performances, which arrived at the evaluation of the proposed control strategy. The results are presented for typical conditions, for weak-grid and for non-linear local load, in order to verify the behavior of the controller against such situations. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

Dependence of intermetallic compound formation on the sublayer stacking sequence in Ag–Sn bilayer thin films

International Nuclear Information System (INIS)

Rossi, P.J.; Zotov, N.; Bischoff, E.; Mittemeijer, E.J.

2016-01-01

Intermetallic compound (IMC) formation in thermally-evaporated Ag–Sn bilayer thin films has been investigated employing especially X-ray diffraction (XRD) and (S)TEM methods. The specific IMCs that are present in the as-deposited state depend sensitively on the stacking sequence of the sublayers. In case of Sn on top of Ag, predominantly Ag 3 Sn is formed, whereas Ag 4 Sn is predominantly present in the as-deposited state for Ag on top of Sn. In the latter case this is accompanied by an extremely fast uptake of a large amount of Sn by the Ag sublayer, leaving behind macroscopic voids in the Sn sublayer. The results are discussed on the basis of the thermodynamics and kinetics of (IMC) product-layer growth in thin films. It is shown that both thermodynamic and kinetic arguments explain the contrasting phenomena observed.

Trace and rare earth elemental variation in Arabian Sea sediments through a transect across the oxygen minimum zone

Digital Repository Service at National Institute of Oceanography (India)

Nath, B.N.; Bau, M.; Rao, B.R.; Rao, Ch.M.

with the sediments from local gneissic sources (Rao and Rao, 1995). 3. ANALYTICAL METHODS Calcium carbonate content of the samples was determined by the Karbonate-Bombe method (MueUer and Gastner, 1971 ) and organic carbon by the wet oxidation method (El Wakeel... analytical results, which is generally better than 4% for all the elements, except for Zr and Th (<8%). Comparison to reference data (Govindaraju, 1994) and to data determined by Garbe-Shoenberg (1993) em- ploying ICP-MS shows that our results...

Information letter 12. Information about operation of Jadrova vyradovacia spolocnost, a.s. and plants SE-NPP Bohunice during December 2006

International Nuclear Information System (INIS)

2007-01-01

In this leaflet results of exploitation of four units of the Bohunice V1 and V2 NPPs are presented. The electricity and heat production in December 2006 are reviewed. Within a December 2006 the electricity was produced in NPP V1: 301.221 GWh (block 1), 281.125 GWh (block 2), totally 582.346 GWh, and 6179.205 GWh within a January - December 2006. Within a November 2006 the NPP V2: the block 3 and block 4 has worked in stabile regime according to needs of regulation. Processing and storage of radioactive wastes in Jadrova vyradovacia spolocnost (JAVYS) is presented. Twenty pieces of fibre-concrete containers were processed into fibre-concrete containers in Bohunice processing centre of radioactive wastes (BSC RAO) in December 2006. Eight fibre-concrete containers were stored into Republic storage of radioactive wastes (RU RAO). Total number in RU RAO reached 1260 pieces of fibre-concrete containers, which represent 17.50 per cent of storage capacity (7200 containers)

Evaluation Codes from Order Domain Theory

DEFF Research Database (Denmark)

Andersen, Henning Ejnar; Geil, Hans Olav

2008-01-01

bound is easily extended to deal with any generalized Hamming weights. We interpret our methods into the setting of order domain theory. In this way we fill in an obvious gap in the theory of order domains. [28] T. Shibuya and K. Sakaniwa, A Dual of Well-Behaving Type Designed Minimum Distance, IEICE......The celebrated Feng-Rao bound estimates the minimum distance of codes defined by means of their parity check matrices. From the Feng-Rao bound it is clear how to improve a large family of codes by leaving out certain rows in their parity check matrices. In this paper we derive a simple lower bound...... on the minimum distance of codes defined by means of their generator matrices. From our bound it is clear how to improve a large family of codes by adding certain rows to their generator matrices. The new bound is very much related to the Feng-Rao bound as well as to Shibuya and Sakaniwa's bound in [28]. Our...

Information letter 10. Information about operation of Jadrova vyradovacia spolocnost, a.s. and plants SE-NPP Bohunice during October 2006

International Nuclear Information System (INIS)

2006-11-01

In this leaflet results of exploitation of four units of the Bohunice V1 and V2 NPPs are presented. The electricity and heat production in October 2006 are reviewed. Within a October 2006 the electricity was produced in NPP V1: 313.778 GWh (block 1), 209.838 GWh (block 2), totally 523.616 GWh, and 5125.651 GWh within a January - October 2006. Within a October 2006 the NPP V2: blocks 3 and 4 has worked on nominal power. Processing and storage of radioactive wastes in Jadrova vyradovacia spolocnost (JAVYS) is presented. Seventeen pieces of fibre-concrete containers were processed into fibre-concrete containers in Bohunice processing centre of radioactive wastes (BSC RAO) in October 2006. Thirty-eight fibre-concrete containers were stored into Republic storage of radioactive wastes (RU RAO). Total number in RU RAO reached 1234 pieces of fibre-concrete containers, which represent 17.14 percent of storage capacity (7200 containers)

Information letter 1. Information about operation of plants SE-NPP Bohunice and SE-VYZ during January 2006

International Nuclear Information System (INIS)

2006-02-01

In this leaflet results of exploitation of four units of the Bohunice V-1 and V-2 NPPs are presented. The electricity and heat production in January 2006 are reviewed. Within a January 2006 the electricity was produced: 249.149 GWh (block 1), 293.272 GWh (block 2), 305.479 GWh (block 3), 308.378 GWh (block 4), totally 1156 GWh. The heat production in January 2006 was 354 397 GJ. Processing and storage of radioactive wastes in Decommissioning of Nuclear Installations and Spent Fuel and Rad-waste Management (SE-VYZ) is presented. Twenty-two pieces of fibre-concrete containers were processed into fibre-concrete containers in Bohunice processing centre of radioactive wastes (BSC RAO) in January 2006. Sixteen fibre-concrete containers were stored into Republic storage of radioactive wastes (RU RAO). Total number in RU RAO reached 1048 pieces of fibre-concrete containers, which represent 14.55 per cent of storage capacity (7200 containers)

Cirurgia valvar e coronária simultânea Combined coronary and valvular surgery

Directory of Open Access Journals (Sweden)

Pablo M. A Pomerantzeff

1994-12-01

Full Text Available Este trabalho analisa 172 pacientes consecutivos operados de cirurgia valvar e coronária simultânea, no período compreendido entre julho de 1980 e junho de 1989.0 número de pacientes submetidos a revascularização do miocárdio e tratamento cirúrgico da valva aórtica (RAo foi de 95, sendo que 75 foram submetidos a tratamento cirúrgico da valva mitral e revascularização do miocárdio (RMi. As lesões valvares mais freqüentes foram a estenose aórtica, 44 casos de insuficiência mitral em 40 casos. O número de anastomoses por paciente foi de 1,87 em média para os pacientes RMi e de 1,56 nos pacientes RAo. A mortalidade hospitalar foi de 9,8% sendo que a mortalidade para os pacientes RAo foi de 7,3% e para os pacientes RMi foi de 12%. Não houve diferença significativa (x²=04423 entre a mortalidade dos pacientes portadores de insuficiência mitral isquémica, operados eletivamente ou em caráter de emergência, sendo a mortalidade de 20% nos eletivos e de 37,5% nos de emergência. Não houve relação entre mortalidade e número de anastomoses por paciente. Houve tendência de melhores resultados com relação à mortalidade nos pacientes RMi com cirurgia conservadora (x²=1,6382. A curva actuarial de sobrevida mostra 82,6% em 19 semestres para os pacientes RMi, 90,4% para os pacientes RAo e 86,3% para o estudo global de pacientes. Com uma evolução de 5172 meses/pacientes, 75% apresentam-se em classe funcional I (NYHA.In the period between July 1980 and June 1989,172 consecutive patients were submitted to combined coronary and valvular surgery. There were patients with predominantly valvular indications and others with predominant coronary indications. In 95 cases, myocardial revascularization and surgical treatment of the aortic valve (RAo were simultaneously performed. Seventy five patients were submitted to myocardial revascularization and surgical treatment of the mitral valve (RMi. The more frequent valvular lesions were

A novel software and conceptual design of the hardware platform for intensity modulated radiation therapy

Energy Technology Data Exchange (ETDEWEB)

Nguyen, Dan; Ruan, Dan; O’Connor, Daniel; Woods, Kaley; Low, Daniel A.; Sheng, Ke, E-mail: ksheng@mednet.ucla.edu [Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, California 90024 (United States); Boucher, Salime [RadiaBeam Technologies, Santa Monica, California 90404 (United States)

2016-02-15

Purpose: To deliver high quality intensity modulated radiotherapy (IMRT) using a novel generalized sparse orthogonal collimators (SOCs), the authors introduce a novel direct aperture optimization (DAO) approach based on discrete rectangular representation. Methods: A total of seven patients—two glioblastoma multiforme, three head & neck (including one with three prescription doses), and two lung—were included. 20 noncoplanar beams were selected using a column generation and pricing optimization method. The SOC is a generalized conventional orthogonal collimators with N leaves in each collimator bank, where N = 1, 2, or 4. SOC degenerates to conventional jaws when N = 1. For SOC-based IMRT, rectangular aperture optimization (RAO) was performed to optimize the fluence maps using rectangular representation, producing fluence maps that can be directly converted into a set of deliverable rectangular apertures. In order to optimize the dose distribution and minimize the number of apertures used, the overall objective was formulated to incorporate an L2 penalty reflecting the difference between the prescription and the projected doses, and an L1 sparsity regularization term to encourage a low number of nonzero rectangular basis coefficients. The optimization problem was solved using the Chambolle–Pock algorithm, a first-order primal–dual algorithm. Performance of RAO was compared to conventional two-step IMRT optimization including fluence map optimization and direct stratification for multileaf collimator (MLC) segmentation (DMS) using the same number of segments. For the RAO plans, segment travel time for SOC delivery was evaluated for the N = 1, N = 2, and N = 4 SOC designs to characterize the improvement in delivery efficiency as a function of N. Results: Comparable PTV dose homogeneity and coverage were observed between the RAO and the DMS plans. The RAO plans were slightly superior to the DMS plans in sparing critical structures. On average, the maximum and

A novel software and conceptual design of the hardware platform for intensity modulated radiation therapy.

Science.gov (United States)

Nguyen, Dan; Ruan, Dan; O'Connor, Daniel; Woods, Kaley; Low, Daniel A; Boucher, Salime; Sheng, Ke

2016-02-01

To deliver high quality intensity modulated radiotherapy (IMRT) using a novel generalized sparse orthogonal collimators (SOCs), the authors introduce a novel direct aperture optimization (DAO) approach based on discrete rectangular representation. A total of seven patients-two glioblastoma multiforme, three head & neck (including one with three prescription doses), and two lung-were included. 20 noncoplanar beams were selected using a column generation and pricing optimization method. The SOC is a generalized conventional orthogonal collimators with N leaves in each collimator bank, where N = 1, 2, or 4. SOC degenerates to conventional jaws when N = 1. For SOC-based IMRT, rectangular aperture optimization (RAO) was performed to optimize the fluence maps using rectangular representation, producing fluence maps that can be directly converted into a set of deliverable rectangular apertures. In order to optimize the dose distribution and minimize the number of apertures used, the overall objective was formulated to incorporate an L2 penalty reflecting the difference between the prescription and the projected doses, and an L1 sparsity regularization term to encourage a low number of nonzero rectangular basis coefficients. The optimization problem was solved using the Chambolle-Pock algorithm, a first-order primal-dual algorithm. Performance of RAO was compared to conventional two-step IMRT optimization including fluence map optimization and direct stratification for multileaf collimator (MLC) segmentation (DMS) using the same number of segments. For the RAO plans, segment travel time for SOC delivery was evaluated for the N = 1, N = 2, and N = 4 SOC designs to characterize the improvement in delivery efficiency as a function of N. Comparable PTV dose homogeneity and coverage were observed between the RAO and the DMS plans. The RAO plans were slightly superior to the DMS plans in sparing critical structures. On average, the maximum and mean critical organ doses were

Supernumerary teeth: literature review | Prasad Rao | Central ...

African Journals Online (AJOL)

://dx.doi.org/10.4314/cajm.v47i1.8588 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News.

Hydrothermal petroleum in the sediments of the Andaman Backarc Basin, Indian Ocean

Digital Repository Service at National Institute of Oceanography (India)

Venkatesan, M.I.; Ruth, E.; Rao, P.S.; Nath, B.N.; Rao, B.R.

inthesediments ofthe AndamanBackarc Basin, IndianOcean § M.I.Venkatesan a, *,E. Ruth b ,P.S. Rao c ,B.N. Nath c , B.R. Rao c a Institute of Geophysics and Planetary Physics and NASA Astrobiology Institute, University of California, Los Angeles, CA 90095-1567, USA... b Dept. of Civil and Environmental Engineering, University of California, Los Angeles, CA 90095-1593, USA c National Institute of Oceanography, Dona Paula, Goa 403 004, India Received 1 March 2002; accepted 13 August 2002 Editorial handling by B...

Trapped Atoms in One-Dimensional Photonic Crystals

Science.gov (United States)

2013-08-09

2002 J. Opt. Soc. Am. B 19 2052 [39] Koenderink A F, Kafesaki M, Soukoulis C M and Sandoghdar V 2006 J. Opt. Soc. Am. B 23 1196 [40] Manga Rao V S C...032509 [55] Hwang J K, Ryu H Y and Lee Y H 1999 Phys. Rev. B 60 4688–95 [56] Yao P, Manga Rao V S C and Hughes S 2010 Laser Photon. Rev. 4 499–516 New Journal of Physics 15 (2013) 083026 (http://www.njp.org/)

Ordered nanoporous silica as carriers for improved delivery of water insoluble drugs: a comparative study between three dimensional and two dimensional macroporous silica

Directory of Open Access Journals (Sweden)

Wang Y

2013-10-01

Full Text Available Ying Wang, Qinfu Zhao, Yanchen Hu, Lizhang Sun, Ling Bai, Tongying Jiang, Siling WangDepartment of Pharmaceutics, Shenyang Pharmaceutical University, Liaoning Province, People’s Republic of ChinaAbstract: The goal of the present study was to compare the drug release properties and stability of the nanoporous silica with different pore architectures as a matrix for improved delivery of poorly soluble drugs. For this purpose, three dimensional ordered macroporous (3DOM silica with 3D continuous and interconnected macropores of different sizes (200 nm and 500 nm and classic mesoporous silica (ie, Mobil Composition of Matter [MCM]-41 and Santa Barbara Amorphous [SBA]-15 with well-ordered two dimensional (2D cylindrical mesopores were successfully fabricated and then loaded with the model drug indomethacin (IMC via the solvent deposition method. Scanning electron microscopy (SEM, N2 adsorption, differential scanning calorimetry (DSC, and X-ray diffraction (XRD were applied to systematically characterize all IMC-loaded nanoporous silica formulations, evidencing the successful inclusion of IMC into nanopores, the reduced crystallinity, and finally accelerated dissolution of IMC. It was worth mentioning that, in comparison to 2D mesoporous silica, 3DOM silica displayed a more rapid release profile, which may be ascribed to the 3D interconnected pore networks and the highly accessible surface areas. The results obtained from the stability test indicated that the amorphous state of IMC entrapped in the 2D mesoporous silica (SBA-15 and MCM-41 has a better physical stability than in that of 3DOM silica. Moreover, the dissolution rate and stability of IMC loaded in 3DOM silica was closely related to the pore size of macroporous silica. The colorimetric 3-(4,5-Dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT and Cell Counting Kit (CCK-8 assays in combination with direct morphology observations demonstrated the good biocompatibility of nanoporous

Physical Climatology of Indonesian Maritime Continent: An Overview of Observational Studies

Science.gov (United States)

Yamanaka, M. D.

2014-12-01

The Indonesian maritime continent (IMC) is a miniature of our land-sea coexisting planet Earth. Firstly, without interior activity, the Earth becomes an even-surfaced "aqua-planet" with both atmosphere and ocean flowing almost zonally, and solar differential heating generates (global thermal tides and) Hadley's meridional circulations with ITCZ along the equator as observed actually over open (Indian and Pacific) oceans in the both sides of IMC. ITCZ involves intraseasonal variations or super cloud clusters moving eastward. Secondly, the lands and seas over the actual Earth have been keeping the area ratio of 3:7 (similar to that of islands and inland/surrounding seas in IMC), but their displacements have produced IMC near the equator, which turns equatorial Pacific easterly current northward (Kuroshio) and reflects equatorial oceanic waves inducing coupled ocean-atmosphere interannual variations such as ENSO and IOD, or displacements of Walker's zonal circulations. Thirdly, because IMC consists of many large/small islands with very long coastlines, many narrow straits become a dam for the global (Pacific to Indian) ocean circulation, and the land-sea heat capacity contrasts along the coastlines generate the world's largest rainfall with diurnal cycles (sea-land breeze circulations). The diurnal cycles are dominant in the rainy season (austral summer in Jawa and Bali), because rainfall-induced sprinkler-like land cooling reverses the trans-coastal temperature gradient before sunrise, and subsequent clear sky on land until around noon provides solar heating dependent on season. These processes lead to rapid land/hydrosphere-atmosphere water exchange, local air pollutant washout, and transequatorial boreal winter monsoon (cold surge). In El Niño years the cooler sea-surface temperature suppresses the morning coastal-sea rainfall, and induces often serious smog over IMC. Lastly, high-resolution observations/models covering both over islands and seas are necessary. A

Concentraciones de LH en periodos de transición reproductiva en cabras criollas x Nubia con diferente condición nutricional

Directory of Open Access Journals (Sweden)

Eliab Estrada-Cortés

2015-01-01

Full Text Available Se determinó el efecto de las reservas corporales de energía (IMC y el consumo diario de alimento (CA, sobre la LH sérica durante las transiciones hacia época anovulatoria (TA y reproductiva (TR. Doce cabras Criollas/ Nubia, ovariectomizadas con implantes s.c. d e 17- ββ ββ β estradiol, se dividieron en dos grupos (n=6, uno de IMC alto (IMCA y otro b ajo (IMCB. Dentro de grupo de IMC se establecieron dos subgrupos (n=3; con restricción de alimento (CRCA y sin restricción temporal (SRCA. Se determinó la frecuencia de pulsos (FPLH, concentración media (CMLH y basal de LH (CBLH. Durante TA se observó disminución gradual de FPLH, CMLH y CBLH (2.08, 1.41, 0.41 pulsos/6 h; 2.1, 1.21, 0.51 ng/ml; 1.3, 0.8, 0.4 ng/ml; P <0.01. En TR aumentaron CMLH y CBLH (1.01, 1.58, 1.87 ng/ ml; 0.57, 0.98, 1.04 ng/ml; P <0.01. Cabras con IMCA presentaron mayor FPLH que las de IMCB durante TA (2.05 vs 0.55 pulsos/6 h; P <0.05 y TR (3.2 vs 0.9 pulsos/6 h; P<0.01 y mayor CMLH durante TR (2.1 vs 0.87 ng/ml; P <0.01. Durante TA, la restricción en CA provocó disminución más temprana de CMLH y CBLH en cabras con IMCA ( P <0.05, haciéndolas similares a cabras con IMCB. Independientemente del IMC, durante TR la restricción en CA disminuyó FPLH y CBLH ( P <0.05. En c abras criollas cruzadas, la secreción de LH es modulada por el IMC y el CA durante los periodos de transición reproductiva . A su vez durante TA, la restricción temporal en CA puede disminuir la secreción de LH aún en cabras con IMC alto.

Proceedings of the Ship Control Systems Symposium (9th) Held in Bethesda, Maryland on 10-14 September 1990. Theme: Automation in Surface Ship Control Systems, Today’s Applications and Future Trends. Volume 1

Science.gov (United States)

1990-09-14

8217 training, and discuss ’the climate for similar advances in the near and long term. 2. INTRODUCTION For the first half of this century, marine plant...5. THE CLIMATE FOR IMCS ADVANCEMENT Over the next decade, the greatest attention will be paid to the in-service aspects of IMCS. The tasks of...HYDRAULIC FLAT BELT (STEEL REINFORCE[)) I•V MOVING WE4ýIGHGT AULIC BUFFER UNIT UNIT Figure 2 - Hull Section - Moving Weight Instillation Vith a

Microstructural Evolution and Mechanical Behavior of High Temperature Solders: Effects of High Temperature Aging

Science.gov (United States)

Hasnine, M.; Tolla, B.; Vahora, N.

2018-04-01

This paper explores the effects of aging on the mechanical behavior, microstructure evolution and IMC formation on different surface finishes of two high temperature solders, Sn-5 wt.% Ag and Sn-5 wt.% Sb. High temperature aging showed significant degradation of Sn-5 wt.% Ag solder hardness (34%) while aging has little effect on Sn-5 wt.% Sb solder. Sn-5 wt.% Ag experienced rapid grain growth as well as the coarsening of particles during aging. Sn-5 wt.% Sb showed a stable microstructure due to solid solution strengthening and the stable nature of SnSb precipitates. The increase of intermetallic compound (IMC) thickness during aging follows a parabolic relationship with time. Regression analysis (time exponent, n) indicated that IMC growth kinetics is controlled by a diffusion mechanism. The results have important implications in the selection of high temperature solders used in high temperature applications.

Methods for coupling radiation, ion, and electron energies in grey Implicit Monte Carlo

International Nuclear Information System (INIS)

Evans, T.M.; Densmore, J.D.

2007-01-01

We present three methods for extending the Implicit Monte Carlo (IMC) method to treat the time-evolution of coupled radiation, electron, and ion energies. The first method splits the ion and electron coupling and conduction from the standard IMC radiation-transport process. The second method recasts the IMC equations such that part of the coupling is treated during the Monte Carlo calculation. The third method treats all of the coupling and conduction in the Monte Carlo simulation. We apply modified equation analysis (MEA) to simplified forms of each method that neglects the errors in the conduction terms. Through MEA we show that the third method is theoretically the most accurate. We demonstrate the effectiveness of each method on a series of 0-dimensional, nonlinear benchmark problems where the accuracy of the third method is shown to be up to ten times greater than the other coupling methods for selected calculations

Two degree of freedom internal model control-PID design for LFC of power systems via logarithmic approximations.

Science.gov (United States)

Singh, Jay; Chattterjee, Kalyan; Vishwakarma, C B

2018-01-01

Load frequency controller has been designed for reduced order model of single area and two-area reheat hydro-thermal power system through internal model control - proportional integral derivative (IMC-PID) control techniques. The controller design method is based on two degree of freedom (2DOF) internal model control which combines with model order reduction technique. Here, in spite of taking full order system model a reduced order model has been considered for 2DOF-IMC-PID design and the designed controller is directly applied to full order system model. The Logarithmic based model order reduction technique is proposed to reduce the single and two-area high order power systems for the application of controller design.The proposed IMC-PID design of reduced order model achieves good dynamic response and robustness against load disturbance with the original high order system. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

Verification of Stochastic Process Calculi

DEFF Research Database (Denmark)

Skrypnyuk, Nataliya

algorithms for constructing bisimulation relations, computing (overapproximations of) sets of reachable states and computing the expected time reachability, the last for a linear fragment of IMC. In all the cases we have the complexities of algorithms which are low polynomial in the size of the syntactic....... In support of this claim we have developed analysis methods that belong to a particular type of Static Analysis { Data Flow / Pathway Analysis. These methods have previously been applied to a number of non-stochastic process calculi. In this thesis we are lifting them to the stochastic calculus...... of Interactive Markov Chains (IMC). We have devised the Pathway Analysis of IMC that is not only correct in the sense of overapproximating all possible behaviour scenarios, as is usual for Static Analysis methods, but is also precise. This gives us the possibility to explicitly decide on the trade-o between...

Ecuaciones para la evaluación de la composición corporal en niños y adolescentes

Directory of Open Access Journals (Sweden)

Cristian Curilem-Gatica

2016-01-01

Full Text Available Resumen: El uso del índice de masa corporal (IMC es el más masivo a nivel mundial y a pesar de existir recomendaciones para su interpretación en relación al sexo, edad y raza, normalmente se estandariza su entendimiento, aumentando el error en el resultado y en la clasificación del estado nutricional. El uso de la composición corporal entrega información de mayor relevancia que el IMC, siendo la masa grasa y la masa muscular las principales. Esta comunicación presenta una revisión de las ecuaciones existentes y propone aquellas más simples y con menor error de estimación para ser usadas como una herramienta que reemplace o complemente al IMC, favoreciendo una mejor comprensión e interpretación del estado nutricional y nivel de actividad física.

Establishment and characterization of a new cell line of canine inflammatory mammary cancer: IPC-366.

Directory of Open Access Journals (Sweden)

Sara Caceres

Full Text Available Canine inflammatory mammary cancer (IMC shares epidemiologic, histopathological and clinical characteristics with the disease in humans and has been proposed as a natural model for human inflammatory breast cancer (IBC. The aim of this study was to characterize a new cell line from IMC (IPC-366 for the comparative study of both IMC and IBC. Tumors cells from a female dog with clinical IMC were collected. The cells were grown under adherent conditions. The growth, cytological, ultrastructural and immunohistochemical (IHC characteristics of IPC-366 were evaluated. Ten female Balb/SCID mice were inoculated with IPC-366 cells to assess their tumorigenicity and metastatic potential. Chromosome aberration test and Karyotype revealed the presence of structural aberration, numerical and neutral rearrangements, demonstrating a chromosomal instability. Microscopic examination of tumor revealed an epithelial morphology with marked anysocytosis. Cytological and histological examination of smears and ultrathin sections by electron microscopy revealed that IPC-366 is formed by highly malignant large round or polygonal cells characterized by marked atypia and prominent nucleoli and frequent multinucleated cells. Some cells had cytoplasmic empty spaces covered by cytoplasmic membrane resembling capillary endothelial cells, a phenomenon that has been related to s vasculogenic mimicry. IHC characterization of IPC-366 was basal-like: epithelial cells (AE1/AE3+, CK14+, vimentin+, actin-, p63-, ER-, PR-, HER-2, E-cadherin, overexpressed COX-2 and high Ki-67 proliferation index (87.15 %. At 2 weeks after inoculating the IPC-366 cells, a tumor mass was found in 100 % of mice. At 4 weeks metastases in lung and lymph nodes were found. Xenograph tumors maintained the original IHC characteristics of the female dog tumor. In summary, the cell line IPC-366 is a fast growing malignant triple negative cell line model of inflammatory mammary carcinoma that can be used for the

The effect of intermetallic compound morphology on Cu diffusion in Sn-Ag and Sn-Pb solder bump on the Ni/Cu Under-bump metallization

Science.gov (United States)

Jang, Guh-Yaw; Duh, Jenq-Gong

2005-01-01

The eutectic Sn-Ag solder alloy is one of the candidates for the Pb-free solder, and Sn-Pb solder alloys are still widely used in today’s electronic packages. In this tudy, the interfacial reaction in the eutectic Sn-Ag and Sn-Pb solder joints was investigated with an assembly of a solder/Ni/Cu/Ti/Si3N4/Si multilayer structures. In the Sn-3.5Ag solder joints reflowed at 260°C, only the (Ni1-x,Cux)3Sn4 intermetallic compound (IMC) formed at the solder/Ni interface. For the Sn-37Pb solder reflowed at 225°C for one to ten cycles, only the (Ni1-x,Cux)3Sn4 IMC formed between the solder and the Ni/Cu under-bump metallization (UBM). Nevertheless, the (Cu1-y,Niy)6Sn5 IMC was observed in joints reflowed at 245°C after five cycles and at 265°C after three cycles. With the aid of microstructure evolution, quantitative analysis, and elemental distribution between the solder and Ni/Cu UBM, it was revealed that Cu content in the solder near the solder/IMC interface played an important role in the formation of the (Cu1-y,Niy)6Sn5 IMC. In addition, the diffusion behavior of Cu in eutectic Sn-Ag and Sn-Pb solders with the Ni/Cu UBM were probed and discussed. The atomic flux of Cu diffused through Ni was evaluated by detailed quantitative analysis in an electron probe microanalyzer (EPMA). During reflow, the atomic flux of Cu was on the order of 1016-1017 atoms/cm2sec in both the eutectic Sn-Ag and Sn-Pb systems.

Obesidad y Esperanza de Vida en México

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Monteverde, Malena

2008-07-01

Full Text Available La alta y creciente prevalencia de personas obesas y con sobrepeso en los países de América Latina y el Caribe y los mayores riesgos asociados con el padecimiento de ciertas enfermedades crónicas, podrían estar modificando los patrones de mortalidad así como la esperanza de vida de dichas poblaciones. El principal objetivo de nuestro estudio es medir el efecto del sobrepeso y la obesidad sobre la mortalidad en México centrándonos en la población de edades mayores (60 y más años de edad. Nuestro estudio utiliza la información que brinda el Estudio Nacional sobre Salud y Envejecimiento en México (ENASEM, 2001 y 2003. El ENASEM es un estudio de panel con representatividad nacional de las personas de 50 y más años en México. Nuestros resultados indican que el exceso de peso (definido por los dos quintiles superiores del Índice de Masa Corporal –IMC- incrementa el riesgo de mortalidad a los 60 años de edad y más en México. Hasta un 11% de las muertes registradas durante el período 2001-2003 en México dentro del grupo de edad de 60 y más años habrían sido evitables si las personas con exceso de peso (pertenecientes a los dos quintiles superiores de IMC hubiesen tenido el peso ideal (quintil medio o tercer quintil de IMC. A nivel individual se estima que las personas de 60 años con exceso de peso (cuarto y quinto quintiles de IMC viven cuatro años menos, en promedio, que las personas con peso normal (tercer quintil de IMC.

Obesidad y Esperanza de Vida en México

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Malena Monteverde

2008-01-01

Full Text Available La alta y creciente prevalencia de personas obesas y con sobrepeso en los países de América Latina y el Caribe y los mayores riesgos asociados con el padecimiento de ciertas enfermedades crónicas, podrían estar modificando los patrones de mortalidad así como la esperanza de vida de dichas poblaciones. El principal objetivo de nuestro estudio es medir el efecto del sobrepeso y la obesidad sobre la mortalidad en México centrándonos en la población de edades mayores (60 y más años de edad. Nuestro estudio utiliza la información que brinda el Estudio Nacional sobre Salud y Envejecimiento en México (ENASEM, 2001 y 2003. El ENASEM es un estudio de panel con representatividad nacional de las personas de 50 y más años en México. Nuestros resultados indican que el exceso de peso (definido por los dos quintiles superiores del Índice de Masa Corporal –IMC- incrementa el riesgo de mortalidad a los 60 años de edad y más en México. Hasta un 11% de las muertes registradas durante el período 2001-2003 en México dentro del grupo de edad de 60 y más años habrían sido evitables si las personas con exceso de peso (pertenecientes a los dos quintiles superiores de IMC hubiesen tenido el peso ideal (quintil medio o tercer quintil de IMC. A nivel individual se estima que las personas de 60 años con exceso de peso (cuarto y quinto quintiles de IMC viven cuatro años menos, en promedio, que las personas con peso normal (tercer quintil de IMC.

Comparative study of two skeletal maturation evaluation indexes = Estudo comparativo de dois índices de estimativa da maturação esquelética

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Warmeling, Daiany

2010-01-01

Full Text Available Objetivo: Comparar o índice de maturação esquelética carpal (IMC e o índice vertebral (IMV e verificar a confiabilidade do IMV na determinação desta maturação. Metodologia: Utilizou-se radiografias dos prontuários da disciplina de Ortodontia da UNISUL. A amostra foi composta por 158 radiografias, sendo 79 carpais e 79 cefalométricas em norma lateral, de pacientes com idades variando entre 6 e 18 anos, de ambos os sexos. Para a determinação do IMC utilizou-se o método de Martins e para o IMV, o de Baccetti, Franchi e McNamara Jr. Resultados: Os testes de correlação de Spearman e Pearson mostraram um índice entre IMC e IMV de 0,616 e 0,698, respectivamente, correlação estatisticamente significante para ambos os sexos (P<0,0001. A correlação de Spearman e de Pearson entre o IMC e a idade cronológica foi de 0,775 e 0,974, respectivamente. Já entre o IMV e a idade cronológica foi de 0,563 e 0,717, respectivamente, uma correlação também estatisticamente significante. Conclusão: O IMC é o método mais seguro e confiável de avaliação da maturação esquelética, porém o IMV pode ser usado como método substituto quando houver familiaridade com as alterações morfológicas das vértebras e quando a radiografia carpal não estiver disponível na documentação ortodôntica

El sobrepeso y la obesidad se asocian a mayor prevalencia de síntomas menopaúsicos y deterioro severo de la calidad de vida

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Ivette Romero-Pérez

2014-01-01

Full Text Available Objetivo: establecer en un grupo de mujeres colombianas la asociación entre obesidad y sobrepeso, síntomas menopáusicos y deterioro de la calidad de vida. Metodología: estudio transversal que hace parte del proyecto “Calidad de Vida en la Menopausia y Etnias Colombianas (CAVIMEC”, que involucra mujeres colombianas indígenas, afrodescendientes y mestizas de las costas Caribe y Pacífica. Realizado con la escala Menopause Rating Scale (MRS, versión en español, ya validada en dicho idioma. Aplicada de forma anónima y voluntaria en las comunidades de residencia con visita puerta a puerta. Las mujeres fueron agrupadas según Índice de Masa Corporal (IMC. Resultados: población de estudio: 2167 mujeres. Edad promedio: 48.6±5.9 años. IMC: 25.4±4.2. IMC normal: 44.2 %, bajo peso: 3.5 %, sobrepeso: 40.1 %, obesidad: 12.0 %. Premenopáusicas: 35.0 % y posmenopáusicas: 41.5 %. Edad promedio de menopausia: 47.4±3.7, y número promedio de años desde el último sangrado: 6.0±4.1 años. La edad promedio de menopausia se incrementó levemente con el aumento del IMC (p=0.027. La prevalencia de todos los síntomas menopáusicos y el deterioro de las dimensiones se incrementaron con el aumento en el IMC. El sobrepeso tuvo OR ajustado:1.61 (1.35-1.93 y la obesidad: OR ajustado: 1.40(1.06-1.84 para deterioro severo de la calidad de vida. Conclusiones: el sobrepeso y la obesidad se asociaron a mayor presencia de síntomas menopáusicos, mayor deterioro somático, psicológico, urogenital y mayor deterioro severo de la calidad de vida

Improved anti-tumor activity of a therapeutic melanoma vaccine through the use of the dual COX-2/5-LO inhibitor licofelone

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Silke Neumann

2016-12-01

Full Text Available Immune-suppressive cell populations impair anti-tumor immunity and can contribute to the failure of immune therapeutic approaches. We hypothesized that the non-steroidal anti-inflammatory drug (NSAID licofelone, a dual COX-2/5-LO inhibitor, would improve therapeutic melanoma vaccination by reducing immune-suppressive cell populations. Therefore, licofelone was administered after tumor implantation, either alone or in combination with a peptide vaccine containing a long tyrosinase-related protein (TRP2-peptide and the adjuvant α-galactosylceramide, all formulated into cationic liposomes. Mice immunized with the long-peptide vaccine and licofelone showed delayed tumor growth compared to mice given the vaccine alone. This protection was associated with a lower frequency of immature myeloid cells (IMCs in the bone marrow (BM and spleen of tumor-inoculated mice. When investigating the effect of licofelone on IMCs in vitro, we found that the prostaglandin E2-induced generation of IMCs was decreased in the presence of licofelone. Furthermore, pre-incubation of BM cells differentiated under IMC-inducing conditions with licofelone reduced the secretion of cytokines interleukin (IL-10 and -6 upon LPS stimulation as compared to untreated cells. Interestingly, licofelone increased IL-6 and IL-10 secretion when administered after the LPS stimulus, demonstrating an environment-dependent effect of licofelone. Our findings support the use of licofelone to reduce tumor-promoting cell populations.

Copying you copying me: interpersonal motor co-ordination influences automatic imitation.

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Daniel Joel Shaw

Full Text Available Moving in a co-ordinated fashion with another individual changes our behaviour towards them; we tend to like them more, find them more attractive, and are more willing to co-operate with them. It is generally assumed that this effect on behaviour results from alterations in representations of self and others. Specifically, through neurophysiological perception-action matching mechanisms, interpersonal motor co-ordination (IMC is believed to forge a neural coupling between actor and observer, which serves to blur boundaries in conceptual self-other representations and causes positive views of the self to be projected onto others. An investigation into this potential neural mechanism is lacking, however. Moreover, the specific components of IMC that might influence this mechanism have not yet been specified. In the present study we exploited a robust behavioural phenomenon--automatic imitation--to assess the degree to which IMC influences neural action observation-execution matching mechanisms. This revealed that automatic imitation is reduced when the actions of another individual are perceived to be synchronised in time, but are spatially incongruent, with our own. We interpret our findings as evidence that IMC does indeed exert an effect on neural perception-action matching mechanisms, but this serves to promote better self-other distinction. Our findings demonstrate that further investigation is required to understand the complex relationship between neural perception-action coupling, conceptual self-other representations, and social behaviour.

Average Power and Brightness Scaling of Diamond Raman Lasers

Science.gov (United States)

2012-01-07

J. Appl. Phys. 92(2), 649–653 (2002). 26. J. Smedley , C. Jaye, J. Bohon, T. Rao, and D. A. Fischer, “Laser patterning of diamond. Part II. Surface...nondiamond carbon formation and its removal,” J. Appl. Phys. 105(12), 123108 (2009). 27. J. Smedley , J. Bohon, Q. Wu, and T. Rao, “Laser patterning...Singh, Dianyuan Fan, Jianquan Yao, Robert F. Walter, Proc. of SPIE Vol. 8551, 85510U · © 2012 SPIE CCC code: 0277-786/12/$18 · doi: 10.1117/12.999857 Proc

Russian muscles

International Nuclear Information System (INIS)

Soerheim, Paul

2004-01-01

A tightening of the electric power balance in the Nordic countries and increased focus on the supply reliability have made the power import from Russia increasingly more important. The two most important players in the Russian power market are the state-owned companies RAO UES and RosEnergoAtom. RAO UES has already begun to strengthen its presence in the Nordic market. There are indications that there are limits to the growth of power import from Russia, and the Nordic power market cannot be based on it in the future

Rayleigh lidar observations of double stratopause structure over three different northern hemisphere stations

CSIR Research Space (South Africa)

Sivakumar, V

2006-09-01

Full Text Available observations of double stratopause structure over three different northern hemisphere stations V. Sivakumar1, H. Bencherif1, A. Hauchecorne2, P. Keckhut2, D. N. Rao3, S. Sharma4, H. Chandra4, A. Jayaraman4, and P. B. Rao5 1Laboratoire de l’Atmosphe`re et... des Cyclones, CNRS–UMR 8105, Universite´ de La Re´union, La Reunion, France 2Service d’Ae´ronomie, CNRS, Paris, France 3National Atmospheric Research Laboratory, P. B. No: 123, Tirupati-517 502, India 4Physical Research Laboratory, Navarangapura...

[Migration of industrial radionuclides in soils and benthal deposits at the coastal margins of the temporary waste storage facility (TWSF) of the Northwest Center for Radioactive Waste Management (SevRAO) and its influence on the possible contamination of the sea offshore waters].

Science.gov (United States)

Filonova, A A; Seregin, V A

2014-01-01

For obtaining the integral information about the current radiation situation in the sea offshore waters of the temporary waste storage facility (TWSF) of the Northwest Center for Radioactive Waste Management "SevRAO" in the Andreeva Bay and in the settle Gremikha with a purpose of a comprehensive assessment of its condition there was performed radiation-ecological monitoring of the adjacent sea offshore waters of the TWSF. It was shown that in the territory of industrial sites of the TWSF as a result of industrial activity there are localized areas of pollution by man-made radionuclides. As a result of leaching of radionuclides by tidal stream, snowmelt and rainwater radioactive contamination extends beyond the territory of the sanitary protection zone and to the coastal sea offshore waters. To confirm the coastal pollution of the sea offshore waters the levels of mobility of 90Sr and 137Cs in environmental chains and bond strength of them with the soil and benthal deposits were clarified by determining with the method of detection of the forms of the presence of radionuclides in these media. There was established a high mobility of 137Cs and 90Sr in soils and benthal deposits (desorption coefficient (Kd) of 137Cs and 90Sr (in soils - 0.56 and 0.98), in the sediments - 0.82). The migration of radionuclides in environmental chains can lead to the contamination of the environment, including the sea offshore waters.

NUEN-618 Class Project: Actually Implicit Monte Carlo

Energy Technology Data Exchange (ETDEWEB)

Vega, R. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Brunner, T. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-12-14

This research describes a new method for the solution of the thermal radiative transfer (TRT) equations that is implicit in time which will be called Actually Implicit Monte Carlo (AIMC). This section aims to introduce the TRT equations, as well as the current workhorse method which is known as Implicit Monte Carlo (IMC). As the name of the method proposed here indicates, IMC is a misnomer in that it is only semi-implicit, which will be shown in this section as well.

The Effectiveness of Al-Si Coatings for Preventing Interfacial Reaction in Al - Mg Dissimilar Metal Welding

OpenAIRE

Wang, Yin; Al-Zubaidy, Basem; Prangnell, Philip

2017-01-01

The dissimilar welding of aluminum to magnesium is challenging because of the rapid formation of brittle intermetallic compounds (IMC) at the weld interface. An Al-Si coating interlayer was selected to address this problem, based on thermodynamic calculations that predicted silicon would change the reaction path to avoid formation of the normally observed binary Al-Mg IMC phases (-Al3Mg2 and -Al12Mg17). Long-term static heat treatments confirmed that a Si-rich coating will preferentially pr...

Director of IMCS - National Prize Laureate of Moldova

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Editorial board of the "Computer Science Journal of Moldova"

2012-02-01

Full Text Available Director of the Institute of Mathematics and Computer Science, Vice Editor-in-Chief of CSJM, and our colleague, D.Hab. Svetlana Cojocaru, in 2011 became the National Prize Laureate of Moldova. In accordance with Government decision, this distinction is given for ``outstanding achievements whose results have substantially enriched science, culture and art, had a considerable contribution to promoting a positive image of the country in the international arena, a significant impact on the development of socio-economic, scientific and technical progress, national and world culture.''

Nanostructured Layered Terbium Hydroxide Containing NASIDs: In Vitro Physicochemical and Biological Evaluations.

Science.gov (United States)

Gu, Qing-Yang; Qiu, Xiao; Liu, Jing-Jing; Fu, Min; Chao, Jian-Ping; Ju, Rui-Jun; Li, Xue-Tao

2018-08-01

Diclofenac sodium (abrr. DS) and indomethacin (abrr. IMC) have been intercalated into the layered terbium hydroxide (LTbH) by anion exchange method. Chemical compositions, thermostability, morphology, luminescence property, release behaviors and cytotoxic effects have been investigated. The DS molecules may embed between layers with a bilayered arrangement and the IMC may correspond to a monolayered arrangement. The Tb3+ luminescence in DS-LTbH and IMC-LTbH composites were enhanced compared with LTbH precusor and the luminescence intensity increases with the deprotonation degree. Drug release was measured with HPLC, and LTbH showed sustained release behavior on both drugs. Further In Vitro evaluation were carried out on cancer cells. Cytotoxic effect of LTbH was observed with a sulforhodamine B colorimetric assay on a variety of cancer cell lines, which revealed that the LTbH showed little cytotoxic effect. Results indicate LTbH may offer a potential vehicle as an effective drug delivery system along with diagnostic integration.

Green synthesis, characterization and some physico-chemical studies on a novel intermolecular compound; 4-nitro-o-phenylenediamine-N, N-dimethylaminobenzaldehyde system

Science.gov (United States)

Rai, U. S.; Singh, Manjeet; Rai, R. N.

2017-09-01

An inter-molecular compound (IMC) L1 was synthesized by taking 1:1 molar ratio of p-nitro-o-phenylenediamine (NOPDA) and N, N-dimethylaminobenzaldehyde (DMAB) via thermally initiated solid state reaction. It was characterized by X-ray diffraction, spectral and optical studies. The single crystal of the (L1) was grown from saturated solution of ethanol using slow evaporation technique at 29 °C. From the single crystal X-ray diffraction analysis, it can be inferred that it crystallizes in triclinic unit cell with P-1 space group (CCDC No 1422765). Absorption spectrum of IMC (L1) shows a band at 318 nm attributed to the intra-molecular charge-transfer (ICT) excited state absorption and the other band at 376 nm is due to n→π* transition. The IMC (L1) shows a strong fluorescence at 418 nm with a Stokes shift (≈100 nm) and quantum efficiency (0.22) upon excitation in methyl alcohol at 318 nm.

Inflammatory mammary carcinoma in 12 dogs: Clinical features, cyclooxygenase-2 expression, and response to piroxicam treatment

Science.gov (United States)

de M. Souza, Carlos H.; Toledo-Piza, Evandro; Amorin, Renee; Barboza, Andrigo; Tobias, Karen M.

2009-01-01

Canine inflammatory mammary carcinoma (IMC) is a rare, locally aggressive, highly metastatic tumor that is poorly responsive to treatment. The purposes of this study were to retrospectively evaluate the history, signalment, and clinical signs of dogs with IMC; compare the outcome of affected dogs treated with traditional chemotherapy with those treated with piroxicam; evaluate Cox-2 expression of IMC cells; and correlate Cox-2 expression with outcome based on treatment. Strong cyclooxygenase-2 expression was present in all tumors. Improvement in clinical condition and disease stability was achieved in all dogs treated with piroxicam, with mean and median progression-free survival of 171 and 183 days, respectively. Median survival time of 3 dogs treated with doxorubicin-based protocols was 7 days, which was significantly less than that of dogs treated with piroxicam (median, 185 days). In conclusion, piroxicam should be considered as a single agent for the treatment of dogs with inflammatory mammary carcinoma. PMID:19436636

Excesso de peso e o risco cardiovascular em jovens seguidos por 17 anos: estudo do Rio de Janeiro El exceso de peso y el riesgo cardiovascular en jóvenes seguidos durante 17 años: estudio del Rio de Janeiro Overweight and cardiovascular risk among young adults followed-up for 17 years: the Rio de Janeiro study, Brazil

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Flávia Lopes Fonseca

2010-02-01

Full Text Available FUNDAMENTO: A adoção de medidas de prevenção primária em jovens é de potencial impacto favorável no cenário das doenças cardiovasculares. OBJETIVO: Avaliar a pressão arterial (PA e variáveis de risco cardiovascular em jovens estratificados pelo comportamento do índice de massa corporal (IMC obtido ao longo de 17 anos, desde a infância/adolescência (I/A. MÉTODOS: Três avaliações foram feitas em 115 indivíduos pertencentes à coorte do Estudo do Rio de Janeiro: A1:12,97 ± 1,48 anos; A2:21,90 ± 1,71 anos; A3:30,65 ± 2,00 anos e divididos em três grupos segundo o IMC nas três avaliações: Grupo N (IMC sempre normal; n=46, Grupo L (IMC variável; n=49 e Grupo S/O (IMC sempre aumentado; n=20. Em A1, A2 e A3 foram obtidos PA e IMC. Em A2 e A3, dosados glicose (G e perfil lipídico. Ainda em A2, dosada insulina (INS e calculado HOMA-IR. Em A3 acrescentou-se medida da circunferência abdominal (CA, relação abdômen/quadril (RAQ e percentual de gordura corporal (%GC. RESULTADOS: 1 Grupo S/O apresentou maiores médias de PA aumentada (pFUNDAMENTO: La adopción de medidas de prevención primaria en jóvenes es de potencial impacto favorable en el escenario de las enfermedades cardiovasculares. OBJETIVO: Evaluar la presión arterial (PA y variables de riesgo cardiovascular en jóvenes estratificados por el comportamiento del índice de masa corporal (IMC obtenido a lo largo de 17 años, desde la infancia/adolescencia (I/A. MÉTODOS: Tres evaluaciones se llevaron a cabo en 115 individuos pertenecientes a la cohorte del Estudio del Rio de Janeiro: A1:12,97 ± 1,48 años; A2:21,90 ± 1,71 años; A3:30,65 ± 2,00 años y divididos en tres grupos segundo el IMC en las tres evaluaciones: Grupo N (IMC siempre normal; n=46, Grupo L (IMC variable; n=49 y Grupo S/O (IMC siempre aumentado; n=20. En A1, A2 y A3 se obtuvieron PA e IMC. En A2 y A3, dosificados glucosa (G y perfil lipídico. Todavía en A2, dosificada la insulina (INS y calculado

Antibody-Mediated Targeting of Alpha PDGF Receptor to Inhibit the Progression of Skeletal Micro-Metastases

Science.gov (United States)

2012-10-01

determinants of metastasis. Semin Cancer Biol 2002; 12:89–96. 4. Fidler I. The pathogenesis of cancer metastasis: the “seed and soil ” hypothesis...degrad enviro on os shown shortl either teracti lesion pound as tho in can The (PDG related associ us (17 cer ce cell su used (ImC the tr curren IMC-3...specific soil . In support of this idea we have to  date considerable evidence indicating that migration of  cancer cells into a foreign tissue needs

Physical climatology of Indonesian maritime continent: An outline to comprehend observational studies

Science.gov (United States)

Yamanaka, Manabu D.

2016-09-01

The Indonesian maritime continent (IMC) is a miniature of our land-sea coexisting planet Earth. Firstly, without interior activity, the Earth becomes an even-surfaced "aqua-planet" with both atmosphere and ocean flowing almost zonally, and solar differential heating generates (global thermal tides and) Hadley's meridional circulations with the inter-tropical convergence zone (ITCZ) along the equator as observed actually over the open (Indian and Pacific) oceans on the both sides of the IMC. The ITCZ involves intraseasonal variations or super cloud clusters moving eastward with hierarchical substructures moving also westward. Secondly, the lands and seas over the actual Earth have been keeping the area ratio of 3:7 (similar to that of islands and inland/surrounding seas in the IMC), but their displacements have produced the IMC near the equator, which turns equatorial Pacific easterly ocean current northward (Kuroshio) and reflects equatorial oceanic waves that affect coupled ocean-atmosphere interannual variations such as ENSO and IOD, or displacements of Walker's zonal circulations. Thirdly, because the IMC consists of many large/small islands with very long coastlines, many narrow straits control the global (Pacific to Indian) ocean circulation, and the land-sea heat capacity contrasts along the coastlines generate the world's largest rainfall with diurnal cycles (sea-land breeze circulations). The diurnal cycles are dominant even in the rainy season (austral summer in Jawa and Bali), because rainfall-induced sprinkler-like land cooling reverses the trans-coastal temperature gradient before sunrise, and subsequent clear sky on land until around noon provides solar heating dependent on season. These processes lead to rapid land/hydrosphere-atmosphere water exchange, local air pollutant washout, and transequatorial boreal winter monsoon (cold surge). In El Niño years, for example, the cooler sea-surface temperature suppresses the morning coastal-sea rainfall, and

Effect of Interfacial Reaction on the Mechanical Performance of Steel to Aluminum Dissimilar Ultrasonic Spot Welds

Science.gov (United States)

Xu, Lei; Wang, Li; Chen, Ying-Chun; Robson, Joe D.; Prangnell, Philip B.

2016-01-01

The early stages of formation of intermetallic compounds (IMC) have been investigated in dissimilar aluminum to steel welds, manufactured by high power (2.5 kW) ultrasonic spot welding (USW). To better understand the influence of alloy composition, welds were produced between a low-carbon steel (DC04) and two different aluminum alloys (6111 and 7055). The joint strengths were measured in lap shear tests and the formation and growth behavior of IMCs at the weld interface were characterized by electron microscopy, for welding times from 0.2 to 2.4 seconds. With the material combinations studied, the η (Fe2Al5) intermetallic phase was found to form first, very rapidly in the initial stage of welding, with a discontinuous island morphology. Continuous layers of η and then θ (FeAl3) phase were subsequently seen to develop on extending the welding time to greater than 0.7 second. The IMC layer formed in the DC04-AA7055 combination grew thicker than for the DC04-AA6111 welds, despite both weld sets having near identical thermal histories. Zinc was also found to be dissolved in the IMC phases when welding with the AA7055 alloy. After post-weld aging of the aluminum alloy, fracture in the lap shear tests always occurred along the joint interface; however, the DC04-AA6111 welds had higher fracture energy than the DC04-AA7055 combination.

Synthesis and studies on structural, optical and nonlinear optical properties of novel organic inter-molecular compounds: 4-chloro-3-nitroaniline-3-hydroxy benzaldehyde and urea-4-dimethylaminopyridine

Science.gov (United States)

Pandey, Priyanka; Rai, R. N.

2018-05-01

Two novel organic inter-molecular compounds (IMCs), (3-(4-chloro-3-nitrophenylimino) methyl) phenol) (CNMP) and urea ̶ 4-dimethylaminopyridine complex (UDMAP), have been synthesized by solid state reaction. These two IMCs were identified by phase diagram study of CNA-HB and U-DMAP systems. The single crystals of newly obtained IMCs were grown by slow solvent evaporation technique at room temperature. Both the IMCs were further studied for their thermal, spectral, single crystal XRD for their atomic packing in molecule, crystallinity, optical and nonlinear optical behaviour. In both the cases, melting point of inter-molecular compounds was found to be higher than that of their parent components, CNMP was found to be thermally stable up to 158 °C while UDMAP was stable up to 144 °C, which indicate their extra stability than their parents. The single crystal XRD studies confirmed that CNMP has crystallized in orthorhombic unit cell with non-centrosymmetric space group P212121 while UDMAP has crystallized in monoclinic unit cell with centrosymmetric space group C2/c. The absorption spectrum of CNMP was found to be in between the absorption of parents, while broadening of peak and red shift was observed in UDMAP as compared to the parents. Second order nonlinear optical property of CNMP and UDMAP was studied using Kurtz Perry powder technique and intense green light emission was observed with CNMP on excitation with 1064 nm of Nd:YAG laser while no emission was observed with UDMAP.

Effect of dual laser beam on dissimilar welding-brazing of aluminum to galvanized steel

Science.gov (United States)

Mohammadpour, Masoud; Yazdian, Nima; Yang, Guang; Wang, Hui-Ping; Carlson, Blair; Kovacevic, Radovan

2018-01-01

In this investigation, the joining of two types of galvanized steel and Al6022 aluminum alloy in a coach peel configuration was carried out using a laser welding-brazing process in dual-beam mode. The feasibility of this method to obtain a sound and uniform brazed bead with high surface quality at a high welding speed was investigated by employing AlSi12 as a consumable material. The effects of alloying elements on the thickness of intermetallic compound (IMC) produced at the interface of steel and aluminum, surface roughness, edge straightness and the tensile strength of the resultant joint were studied. The comprehensive study was conducted on the microstructure of joints by means of a scanning electron microscopy and EDS. Results showed that a dual-beam laser shape and high scanning speed could control the thickness of IMC as thin as 3 μm and alter the failure location from the steel-brazed interface toward the Al-brazed interface. The numerical simulation of thermal regime was conducted by the Finite Element Method (FEM), and simulation results were validated through comparative experimental data. FEM thermal modeling evidenced that the peak temperatures at the Al-steel interface were around the critical temperature range of 700-900 °C that is required for the highest growth rate of IMC. However, the time duration that the molten pool was placed inside this temperature range was less than 1 s, and this duration was too short for diffusion-control based IMC growth.

Effects of Insert Metal Type on Interfacial Microstructure During Dissimilar Joining of TiAl Alloy to SCM440 by Friction Welding

Science.gov (United States)

Park, Jong-Moon; Kim, Ki-Young; Kim, Kyoung-Kyun; Ito, Kazuhiro; Takahashi, Makoto; Oh, Myung-Hoon

2018-03-01

Although the welding zone of direct bonding between a TiAl alloy and SCM440 can be obtained by friction welding, martensitic transformation and the formation of intermetallic compounds (IMCs) and cracks result in a lower tensile strength of the joints relative to those of other welding techniques. Insert metals were used as a buffer layer to relieve stress while increasing the bond strength. In this study, the microstructure and mechanical properties on welded joints of a TiAl alloy and SCM440 with various insert metals, were investigated. The TiAl/Cu/SCM440 and TiAl/Ni/SCM440 joints were fabricated using a servo-motor-type friction welding machine. As a result, it was confirmed that the formation of a welding flash was dependent on the insert metal type, and the strength of the base metal. At the TiAl/Cu/SCM440 interface, the formation of IMCs CuTiAl and Cu2TiAl was observed at TiAl/Cu, while no IMC formation was observed at Cu/SCM440. On the other hand, at the TiAl/Ni/SCM440 interface, several IMCs with more than 100 μm thickness were found, and roughly two compositions, viz., Ti2NiAl3 and TiNi2Al, were observed at the TiAl/Ni interface. At the Ni/SCM440 interface, 10 μm-thick FeNi and others were found.

Effects of Insert Metal Type on Interfacial Microstructure During Dissimilar Joining of TiAl Alloy to SCM440 by Friction Welding

Science.gov (United States)

Park, Jong-Moon; Kim, Ki-Young; Kim, Kyoung-Kyun; Ito, Kazuhiro; Takahashi, Makoto; Oh, Myung-Hoon

2018-05-01

Although the welding zone of direct bonding between a TiAl alloy and SCM440 can be obtained by friction welding, martensitic transformation and the formation of intermetallic compounds (IMCs) and cracks result in a lower tensile strength of the joints relative to those of other welding techniques. Insert metals were used as a buffer layer to relieve stress while increasing the bond strength. In this study, the microstructure and mechanical properties on welded joints of a TiAl alloy and SCM440 with various insert metals, were investigated. The TiAl/Cu/SCM440 and TiAl/Ni/SCM440 joints were fabricated using a servo-motor-type friction welding machine. As a result, it was confirmed that the formation of a welding flash was dependent on the insert metal type, and the strength of the base metal. At the TiAl/Cu/SCM440 interface, the formation of IMCs CuTiAl and Cu2TiAl was observed at TiAl/Cu, while no IMC formation was observed at Cu/SCM440. On the other hand, at the TiAl/Ni/SCM440 interface, several IMCs with more than 100 μm thickness were found, and roughly two compositions, viz., Ti2NiAl3 and TiNi2Al, were observed at the TiAl/Ni interface. At the Ni/SCM440 interface, 10 μm-thick FeNi and others were found.

Estimation of tropical cyclone heat potential in the Bay of Bengal and its role in the genesis and intensification of storms

Digital Repository Service at National Institute of Oceanography (India)

Sadhuram, Y.; Murthy, T.V.R.; Somayajulu, Y.K.

in the intensification of a storm. Warm layers of 26?C extended at least 100 m beneath the surface in these oceanic features which represent high heat potential (> 90 kJ/cm2) in the western Gulf of Mexico8,9. Monitoring of warm and cold core eddies and the regions... of Mexico, J.Phys.Oceonogr, 2 (1972) 218-224. 4 Palmen E, On the formation and structure of tropical cyclones, Geophysics, 3 (1948) 26-38. 5 Sadhuram Y, Rao B P, Rao D P, Shastri P N M & Subrahmanyam M V, Seasonal variability of cyclone heat potential...

On semi star generalized closed sets in bitopological spaces.

Directory of Open Access Journals (Sweden)

K. Kannan

2010-07-01

Full Text Available K. Chandrasekhara Rao and K. Joseph [5] introduced the concepts of semi star generalized open sets and semi star generalized closed sets in a topological space. The same concept was extended to bitopological spaces by K. Chan-drasekhara Rao and K. Kannan [6,7]. In this paper, we continue the study of τ1τ2-s∗g closed sets inbitopology and we introduced the newly related concept of pairwise s∗g-continuous mappings. Also S∗GO-connectedness and S∗GO-compactness are introduced in bitopological spaces and some of their properties are established.

BIASED BEARINGS-ONIKY PARAMETER ESTIMATION FOR BISTATIC SYSTEM

Institute of Scientific and Technical Information of China (English)

Xu Benlian; Wang Zhiquan

2007-01-01

According to the biased angles provided by the bistatic sensors,the necessary condition of observability and Cramer-Rao low bounds for the bistatic system are derived and analyzed,respectively.Additionally,a dual Kalman filter method is presented with the purpose of eliminating the effect of biased angles on the state variable estimation.Finally,Monte-Carlo simulations are conducted in the observable scenario.Simulation results show that the proposed theory holds true,and the dual Kalman filter method can estimate state variable and biased angles simultaneously.Furthermore,the estimated results can achieve their Cramer-Rao low bounds.

Equine recurrent airway obstruction

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Artur Niedźwiedź

2014-10-01

Full Text Available Equine Recurrent Airway Obstruction (RAO, also known as heaves or broken wind, is one of the most common disease in middle-aged horses. Inflammation of the airway is inducted by organic dust exposure. This disease is characterized by neutrophilic inflammation, bronchospasm, excessive mucus production and pathologic changes in the bronchiolar walls. Clinical signs are resolved in 3-4 weeks after environmental changes. Horses suffering from RAO are susceptible to allergens throughout their lives, therefore they should be properly managed. In therapy the most importanthing is to eliminate dustexposure, administration of corticosteroids and use bronchodilators to improve pulmonary function.

Book review: 'Four Decades of Marine Geosciences in India - A Retrospect, National Seminar organised in connection with 150 th year celebration of Geological Survey of India. Mangalore 14-16, March 2001'

Digital Repository Service at National Institute of Oceanography (India)

Rao, V.P

, Geological Survey of India, 27 Jawaharlal Nehru Road, Kolkata - 700 016. 325p, Price INR: 575/-, US$: 32/-, UK?: 20/- Marine Geology is a relatively young branch of Geology. It was initiated in India at the Andhra University, Waltair in the late 40's... group at NIO, Goa. Further, it is not out of place to mention the names of Professors C. Mahadevan, M. Poornachandra Rao and M. Subba Rao from Andhra University, and Shri R.R. Nair and Dr. M.G.A.P. Setty from NIO, Dr. V.V. Sastry from Oil and Natural Gas...

Distribution of uranium and thorium isotopes in iron-manganese concretions of the Pacific ocean

International Nuclear Information System (INIS)

Kuznetsov, V.Yu.; Andreev, S.I.

1995-01-01

Distribution of 238 U, 234 U, 232 Th, 230 Th in cross sections of samples from the Pacific Ocean iron-manganese concretions (IMC) of different genetic types has been studied, the results are presented. Possible influence of diagenetic processes in the deposits mentioned on distribution of the radionuclides in iron-manganese septarian nodules has been considered. The assumption is made that remobilization of Mn, Ni, Cu from IMC containing deposits does not upset uranium and thorium distribution in the concretions resulted from sedimentation mechanism of their formation. 18 refs., 3 tabs

Disentangling the Relationship Between the Adoption of In-Memory Computing and Firm Performance

DEFF Research Database (Denmark)

Fay, Marua; Müller, Oliver; vom Brocke, Jan

2016-01-01

Recent growth in data volume, variety, and velocity led to an increased demand for high-performance data processing and analytics solutions. In-memory computing (IMC) enables organizations to boost their information processing capacity, and is widely acknowledged to be one of the leading strategic...... at explaining the relationship between the adoption of IMC solutions and firm performance. In this research-in-progress paper we discuss the theoretical background of our work, describe the proposed research design, and develop five hypotheses for later testing. Our work aims at contributing to the research...

Análisis de segmentos corporales en niños escolares de 6 14 años de la ciudad de Villaguay

OpenAIRE

Ranieri, José; Giacomino, Marta; Etcheverry, Gregorio; Balderrain, Andrés; Sivak, Jorgelina

2009-01-01

En la actualidad en los datos estadísticos provenientes de varias regiones de América Latina reflejan incremento en la prevalencia de desnutrición. Si bien para la evaluación del estado nutricional de una población el Índice de Masa Corporal (IMC) es un excelente indicador, hay autores que consideran que la talla es mejor indicador en la deprivación urbana, generalmente debido a la influencia de factores étnicos y ambientales en el IMC, recomendando acompañarlo en los casos de malnutrición co...

Comparative study of the influence of antimony oxide additives (III) and nickel hydroxide (II) on electrochemical behavior of cadmium electrodes

Energy Technology Data Exchange (ETDEWEB)

Kadnikova, N.V.; Lvova, L.A.; Ryabskaya, I.A.

1983-01-01

Comparative study of the influence of additives indicated that with partial or complete replacement in the active mass of the cadmium electrode of nickel hydroxide (II) by antimony oxide (III), the electrochemical characteristics do not significantly change. During prolonged storage of charged cadmium electrodes the presence of nickel hydroxide (II) and intermetal compound (IMC) of cadmium with nickel is formed and the specific surface increases. In the case of adding antimony (III) formation of noticeable quantities of IMC of cadmium with antimony is not observed. The specific surface is reduced during storage.

Asymptotic analysis of spatial discretizations in implicit Monte Carlo

International Nuclear Information System (INIS)

Densmore, Jeffery D.

2009-01-01

We perform an asymptotic analysis of spatial discretizations in Implicit Monte Carlo (IMC). We consider two asymptotic scalings: one that represents a time step that resolves the mean-free time, and one that corresponds to a fixed, optically large time step. We show that only the latter scaling results in a valid spatial discretization of the proper diffusion equation, and thus we conclude that IMC only yields accurate solutions when using optically large spatial cells if time steps are also optically large. We demonstrate the validity of our analysis with a set of numerical examples.

Consumo de bebidas energéticas, alcohólicas y azucaradas en jóvenes universitarios de la frontera México-USA

OpenAIRE

Gómez-Miranda, Luis Mario; Bacardí-Gascón, Montserrat; Caravalí-Meza, Nuris Yohana; Jiménez-Cruz, Arturo

2015-01-01

Introducción: El consumo de bebidas azucaradas, energéticas y alcohólicas en universitarios puede ser un riesgo para la salud. Objetivo: Determinar el consumo de bebidas azucaradas, energéticas, y alcohólicas y compararlo con el estado del IMC en universitarios. Metodología: Se evaluaron estudiantes de segundo y tercer año de la UABC. Se midieron el peso, la talla y la circunferencia de cintura, y se calculó el IMC. Se aplicó un cuestionario sobre consumo de 19 bebidas. Resultados: Participar...

Sensibilidade e especificidade dos sistemas de classificação para sobrepeso baseados no índice de massa corporal em crianças de 7-10 anos de idade.

Directory of Open Access Journals (Sweden)

Danielle Biazzi Leal

2013-03-01

Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2013v15n3p267   O objetivo deste estudo foi comparar a sensibilidade e especificidadede sistemas de classificação baseados no índice de massa corporal (IMC na detecção do excesso degordura corporal em escolares. Um total de 2795 escolares com idade entre sete a dez anos foram examinados. O excesso de gordura corporal foi definido como os resíduos padronizados do somatório de três dobras cutâneas iguais ou superiores ao percentil 90. Os sistemas internacionais baseados no IMC recomendados pela International Obesity Task Force (IOTF e Organização Mundial de Saúde (OMS-2007 foram avaliados com base emsua sensibilidade e especificidade para detecção do excesso de gordura corporal e comparado com uma referência do IMC nacional (Brasil-2006. Análise das razões de verossimilhança positiva (RV+ e negativa (RV- também foi utilizada para comparar as precisões diagnósticas dos três critérios do IMC. Os três sistemas de classificação apresentaram sensibilidade (78,4-98,6% e especificidade (75,9-91,6% moderadamente alta para ambos os sexos. No geral,os três sistemas de classificação apresentaram valores de RV+ e RV-, condizentes com umdiagnóstico de evidência moderada para o sobrepeso (RV+ acima de cinco e RV- abaixo de 0,2. Os resultados mostraram que os três sistemas de classificação do IMC podem ser usados como instrumentos de rastreio do excesso de gordura corporal. Entretanto, o desempenho do sistema de classificação Brasil-2006 foi superior porque mostrou o melhor equilíbrio entre os índices de acurácia diagnóstica.

Diffusion barrier characteristics and shear fracture behaviors of eutectic PbSn solder/electroless Co(W,P) samples

International Nuclear Information System (INIS)

Pan, Hung-Chun; Hsieh, Tsung-Eong

2012-01-01

Highlights: ► Diffusion barrier features, activation energies of IMC growth and mechanical behaviors of electroless Co(W,P)/PbSn joints. ► Amorphous Co(W,P) is a sacrificial- plus stuffed-type barrier while polycrystalline Co(W,P) is a sacrificial-type barrier. ► Ductile mode dominates the failure of Co(W,P)/PbSn joints. ► Phosphorus content of Co(W,P) is crucial to the barrier capability and microstructure evolution at Co(W,P)/PbSn interface. ► Diffusion barrier capability is governed by the nature of chemical bonds, rather than the crystallinity of materials. - Abstract: Diffusion barrier characteristics, activation energy (E a ) of IMC growth and bonding properties of amorphous and polycrystalline electroless Co(W,P) (termed as α-Co(W,P) and poly-Co(W,P)) to eutectic PbSn solder are presented. Intermetallic compound (IMC) spallation and an nano-crystalline P-rich layer were observed in PbSn/α-Co(W,P) samples subjected to liquid-state aging at 250 °C. In contrast, IMCs resided on the P-rich layer in PbSn/α-Co(W,P) samples subjected to solid-state aging at 150 °C. Thick IMCs neighboring to an amorphous W-rich layer was seen in PbSn/poly-Co(W,P) samples regardless of the aging type. α-Co(W,P) was found to be a sacrificial- plus stuffed-type barrier while poly-Co(W,P) is mainly a sacrificial-type barrier. The values of E a 's for PbSn/α-Co(W,P) and PbSn/poly-Co(W,P) systems were 338.6 and 167.5 kJ/mol, respectively. Shear test revealed the ductile mode dominates the failure in both α- and poly-Co(W,P) samples. Analytical results indicated the high P content in electroless layer might enhance the barrier capability but degrade the bonding strength.

Outcomes after liquid nitrogen spray cryotherapy in Barrett's esophagus-associated high-grade dysplasia and intramucosal adenocarcinoma: 5-year follow-up.

Science.gov (United States)

Ramay, Fariha H; Cui, Qingping; Greenwald, Bruce D

2017-10-01

Liquid nitrogen spray cryotherapy (LNSCT) has been shown to be a safe, well-tolerated, and effective therapy for Barrett's esophagus (BE)-associated high-grade dysplasia (BE-HGD) and intramucosal adenocarcinoma (IMC). Long-term follow-up is lacking. The aim of this study was to assess the efficacy, durability, and rate of neoplastic progression after LNSCT in BE-HGD/IMC at 3 and 5 years. In this single-center, retrospective study drawn from a prospective database, patients with BE-HGD/IMC of any length treated with LNSCT were followed with surveillance endoscopy with biopsy for 3 to 5 years. Patients with IMC completely removed by endoscopic resection were included. Outcome measures included complete eradication of HGD (CE-HGD), dysplasia, and intestinal metaplasia; incidence rates; durability of response; location of recurrent intestinal metaplasia and dysplasia; and rate of disease progression. A total of 50 and 40 patients were included in 3-year and 5-year analyses. Initial CE-HGD, dysplasia, and intestinal metaplasia achieved in 98%, 90%, and 60%, respectively. Overall CE-HGD, dysplasia, and intestinal metaplasia at 3 years were 96% (48/50), 94% (47/50), and 82% (41/50), and at 5 years were 93% (37/40), 88% (35/40), and 75% (30/40). Incidence rates of recurrent intestinal metaplasia, dysplasia, and HGD/esophageal adenocarcinoma per person-year of follow-up after initial complete eradication of intestinal metaplasia (CE-IM) were 12.2%, 4.0%, and 1.4% per person-year for the 5-year cohort. Most recurrences were found immediately below the neosquamocolumnar junction. Two of 7 HGD recurrences occurred later than 4 years after initial eradication, and 2 patients (4%) progressed to adenocarcinoma despite treatment. In patients with BE-HGD/IMC, LNSCT is effective in eliminating dysplasia and intestinal metaplasia. Progression to adenocarcinoma was uncommon, and recurrence of dysplasia was successfully treated in most cases. Long-term surveillance is necessary to

Incorporation of Interfacial Intermetallic Morphology in Fracture Mechanism Map for Sn-Ag-Cu Solder Joints

Science.gov (United States)

Huang, Z.; Kumar, P.; Dutta, I.; Sidhu, R.; Renavikar, M.; Mahajan, R.

2014-01-01

A fracture mechanism map (FMM) is a powerful tool which correlates the fracture behavior of a material to its microstructural characteristics in an explicit and convenient way. In the FMM for solder joints, an effective thickness of the interfacial intermetallic compound (IMC) layer ( t eff) and the solder yield strength ( σ ys,eff) are used as abscissa and ordinate axes, respectively, as these two predominantly affect the fracture behavior of solder joints. Earlier, a definition of t eff, based on the uniform thickness of IMC ( t u) and the average height of the IMC scallops ( t s), was proposed and shown to aptly explain the fracture behavior of solder joints on Cu. This paper presents a more general definition of t eff that is more widely applicable to a range of metallizations, including Cu and electroless nickel immersion gold (ENIG). Using this new definition of t eff, mode I FMM for SAC387/Cu joints has been updated and its validity was confirmed. A preliminary FMM for SAC387/Cu joints with ENIG metallization is also presented.

Towards a frequency-dependent discrete maximum principle for the implicit Monte Carlo equations

Energy Technology Data Exchange (ETDEWEB)

Wollaber, Allan B [Los Alamos National Laboratory; Larsen, Edward W [Los Alamos National Laboratory; Densmore, Jeffery D [Los Alamos National Laboratory

2010-12-15

It has long been known that temperature solutions of the Implicit Monte Carlo (IMC) equations can exceed the external boundary temperatures, a so-called violation of the 'maximum principle.' Previous attempts at prescribing a maximum value of the time-step size {Delta}{sub t} that is sufficient to eliminate these violations have recommended a {Delta}{sub t} that is typically too small to be used in practice and that appeared to be much too conservative when compared to numerical solutions of the IMC equations for practical problems. In this paper, we derive a new estimator for the maximum time-step size that includes the spatial-grid size {Delta}{sub x}. This explicitly demonstrates that the effect of coarsening {Delta}{sub x} is to reduce the limitation on {Delta}{sub t}, which helps explain the overly conservative nature of the earlier, grid-independent results. We demonstrate that our new time-step restriction is a much more accurate means of predicting violations of the maximum principle. We discuss how the implications of the new, grid-dependent timestep restriction can impact IMC solution algorithms.

Towards a frequency-dependent discrete maximum principle for the implicit Monte Carlo equations

International Nuclear Information System (INIS)

Wollaber, Allan B.; Larsen, Edward W.; Densmore, Jeffery D.

2011-01-01

It has long been known that temperature solutions of the Implicit Monte Carlo (IMC) equations can exceed the external boundary temperatures, a so-called violation of the 'maximum principle'. Previous attempts at prescribing a maximum value of the time-step size Δ t that is sufficient to eliminate these violations have recommended a Δ t that is typically too small to be used in practice and that appeared to be much too conservative when compared to numerical solutions of the IMC equations for practical problems. In this paper, we derive a new estimator for the maximum time-step size that includes the spatial-grid size Δ x . This explicitly demonstrates that the effect of coarsening Δ x is to reduce the limitation on Δ t , which helps explain the overly conservative nature of the earlier, grid-independent results. We demonstrate that our new time-step restriction is a much more accurate means of predicting violations of the maximum principle. We discuss how the implications of the new, grid-dependent time-step restriction can impact IMC solution algorithms. (author)

Determination of the scattering coefficient of biological tissue considering the wavelength and absorption dependence of the anisotropy factor

Science.gov (United States)

Fukutomi, Daichi; Ishii, Katsunori; Awazu, Kunio

2016-04-01

The anisotropy factor g, one of the optical properties of biological tissues, has a strong influence on the calculation of the scattering coefficient μ s in inverse Monte Carlo (iMC) simulations. It has been reported that g has the wavelength and absorption dependence; however, few attempts have been made to calculate μ s using g values by taking the wavelength and absorption dependence into account. In this study, the angular distributions of scattered light for biological tissue phantoms containing hemoglobin as a light absorber were measured by a goniometric optical setup at strongly (405 nm) and weakly (664 nm) absorbing wavelengths to obtain g. Subsequently, the optical properties were calculated with the measured values of g by integrating sphere measurements and an iMC simulation, and compared with the results obtained with a conventional g value of 0.9. The μ s values with measured g were overestimated at the strongly absorbing wavelength, but underestimated at the weakly absorbing wavelength if 0.9 was used in the iMC simulation.

Comer mejor y moverse más: programa contra la obesidad y sobrepeso en alumnos del quinto y sexto grado de la escuela primaria “José María Leyva”, Hermosillo, Sonora

Directory of Open Access Journals (Sweden)

Brianda Cecilia Serecer Varela

2015-06-01

Full Text Available El aumento mundial de sobrepeso y obesidad es atribuible a factores como dieta con aumento de la ingesta de alimentos hipercalóricos y disminución de la actividad física. El objetivo fue evaluar un programa de intervención cuya meta era disminuir el IMC en niños de quinto y sexto grado en una escuela primaria de Hermosillo, Sonora. El programa se implementó de diciembre de 2013 a junio de 2014 en tres etapas: por Enfermería, Nutrición, y Cultura física y deporte, y se logró reducir el Índice de Masa Corporal de los escolares (IMC inicial 19.25, IMC final 18.71. De acuerdo a la prueba de Wilcoxon se encontraron diferencias estadísticamente significativas entre el peso inicial y final (p: 00. La implementación de programas multidisciplinarios en la atención contra la obesidad conlleva a la disminución de sobrepeso y obesidad y disminución de factores de riesgo para la salud.

[Not Available].

Science.gov (United States)

Curilem Gatica, Cristian; Almagià Flores, Atilio; Rodríguez Rodríguez, Fernando; Yuing Farias, Tuillang; Berral de la Rosa, Francisco; Martínez Salazar, Cristian; Jorquera Aguilera, Carlos; Bahamondes Ávila, Carlos; Soís Urra, Patricio; Cristi Montero, Carlos; Bruneau Chávez, José; Pinto Aguilante, Juan; Niedmann Brunet, Luis

2016-06-30

El índice de masa corporal (IMC) otorga uno de los índices más usados para determinar el estado nutricional de la población a nivel mundial, donde a pesar de existir recomendaciones claras y definidas para su interpretación como el sexo, edad, raza, entre otros, normalmente se estandariza su clasificación, independiente de las variables, aumentando el error en el resultado y en la clasificación del estado nutricional.El uso de la composición corporal a través de la antropometría entrega mayor información que el IMC, siendo la masa grasa y la masa muscular los principales resultados útiles.Este artículo presenta una revisión de las ecuaciones existentes y propone aquellas más simples y con menor error de estimación para ser usadas como una herramienta que reemplace o complemente al IMC, favoreciendo una mejor comprensión e interpretación del estado nutricional y nivelde actividad física en niños y adolescentes.

Compare Complication of Classic versus Patent Hemostasis in Transradial Coronary Angiography.

Science.gov (United States)

Roghani, Farshad; Tajik, Mohammad Nasim; Khosravi, Alireza

2017-01-01

Coronary artery disease (CAD) is multifactorial disease, in which thrombotic occlusion and calcification occur usually. New strategies have been made for diagnosis and treatment of CAD, such as transradial catheterization. Hemostasis could be done in two approaches: traditional and patent. Our aim is to find the best approach with lowest complication. In a comparative study, 120 patients were recruited and divided randomly into two subgroups, including traditional group (60 patients; 24 females, 36 males; mean age: 64.35 ± 10.56 years) and patent group (60 patients; 28 females, 32 males; mean age: 60.15 ± 8.92 years). All demographic data including age, gender, body mass index, and CAD-related risk factors (smoking, diabetes, hypertension) and technical data including the number of catheters, procedure duration, and hemostatic compression time and clinical outcomes (radial artery occlusion [RAO], hematoma, bleeding) were collected. Data were analyzed by SPSS version 16. Our findings revealed that the incidence of RAO was significantly lower in patent groups compared with traditional group ( P = 0.041). Furthermore, the difference incidence of RAO was higher in early occlusion compare with late one ( P = 0.041). Moreover, there were significant relationship between some factors in patients of traditional group with occlusion (gender [ P = 0.038], age [ P = 0.031], diabetes mellitus [ P = 0.043], hemostatic compression time [ P = 0.036]) as well as in patent group (age [ P = 0.009], hypertension [ P = 0.035]). Our findings showed that RAO, especially type early is significantly lower in patent method compared classic method; and patent hemostasis is the safest method and good alternative for classical method.

Compare Complication of Classic versus Patent Hemostasis in Transradial Coronary Angiography

Directory of Open Access Journals (Sweden)

Farshad Roghani

2017-01-01

Full Text Available Background: Coronary artery disease (CAD is multifactorial disease, in which thrombotic occlusion and calcification occur usually. New strategies have been made for diagnosis and treatment of CAD, such as transradial catheterization. Hemostasis could be done in two approaches: traditional and patent. Our aim is to find the best approach with lowest complication. Materials and Methods: In a comparative study, 120 patients were recruited and divided randomly into two subgroups, including traditional group (60 patients; 24 females, 36 males; mean age: 64.35 ± 10.56 years and patent group (60 patients; 28 females, 32 males; mean age: 60.15 ± 8.92 years. All demographic data including age, gender, body mass index, and CAD-related risk factors (smoking, diabetes, hypertension and technical data including the number of catheters, procedure duration, and hemostatic compression time and clinical outcomes (radial artery occlusion [RAO], hematoma, bleeding were collected. Data were analyzed by SPSS version 16. Results: Our findings revealed that the incidence of RAO was significantly lower in patent groups compared with traditional group (P = 0.041. Furthermore, the difference incidence of RAO was higher in early occlusion compare with late one (P = 0.041. Moreover, there were significant relationship between some factors in patients of traditional group with occlusion (gender [P = 0.038], age [P = 0.031], diabetes mellitus [P = 0.043], hemostatic compression time [P = 0.036] as well as in patent group (age [P = 0.009], hypertension [P = 0.035]. Conclusion: Our findings showed that RAO, especially type early is significantly lower in patent method compared classic method; and patent hemostasis is the safest method and good alternative for classical method.

Information letter 3. Information about operation of plants SE-NPP Bohunice and SE-VYZ during March 2006

International Nuclear Information System (INIS)

2006-04-01

In this leaflet results of exploitation of four units of the Bohunice V-1 and V-2 NPPs are presented. The electricity and heat production in March 2006 are reviewed. Within a March 2006 the electricity was produced: 294.020 GWh (block 1), 287.684 GWh (block 2), 292.636 GWh (block 3), 237.806 GWh (block 4), totally 1112 GWh, and 3330 GWh within a January - March 2005. The heat production in January 2006 was 253 057 GJ, and within a January - March 2006 it was produced 896 226 GJ of heat. Processing and storage of radioactive wastes in Decommissioning of Nuclear Installations and Spent Fuel and Rad-waste Management (SE-VYZ) is presented. Twenty-one pieces of fibre-concrete containers were processed into fibre-concrete containers in Bohunice processing centre of radioactive wastes (BSC RAO) in March 2006. Sixteen fibre-concrete containers were stored into Republic storage of radioactive wastes (RU RAO). Total number in RU RAO reached 1080 pieces of fibre-concrete containers, which represent 15.00 per cent of storage capacity (7200 containers). Celebration of ten years operation of SE-VYZ is described

WITH CITRIC ACID Srinivasa Rao Pedada, Srikanth B

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Review on cadmium removal from aqueous solutions | Rao ...

African Journals Online (AJOL)

More attention needs to be given for regeneration/reuse/ safe disposal of the loaded adsorbents wherein the data are insufficient. The engineering aspects also need attention for commercial application of various adsorbents. International Journal of Engineering, Science and Technology, Vol. 2, No. 7, 2010, pp. 81-103 ...

Appa Rao Podile | Speakers | Indian Academy of Sciences

Indian Academy of Sciences (India)

In the past decade, domain shuf- fling/swapping of recombinant bacterial chitinases, bioprocess development for production of chitooligosaccharides by enzymatic methods, mechanism of elicitor (harpin) induced cell death, nanotechnology for crop protection, and non-host resistance have been his major areas of research ...

Development of a double beam process for joining aluminum and steel

Science.gov (United States)

Frank, Sascha

2014-02-01

Multi-material structures pose an attractive option for overcoming some of the central challenges in lightweight design. An exceptionally high potential for creating cost-effective lightweight solutions is attributed to the combination of steel and aluminum. However, these materials are also particularly difficult to join due to their tendency to form intermetallic compounds (IMCs). The growth of these compounds is facilitated by high temperatures and long process times. Due to their high brittleness, IMCs can severely weaken a joint. Thus, it is only possible to create durable steel-aluminum joints when the formation of IMCs can be limited to a non-critical level. To meet this goal, a new joining method has been designed. The method is based on the combination of a continuous wave (pw) and a pulsed laser (pw) source. Laser beams from both sources are superimposed in a common process zone. This makes it possible to apply the advantages of laser brazing to mixed-metal joints without requiring the use of chemical fluxes. The double beam technology was first tested in bead-on-plate experiments using different filler wire materials. Based on the results of these tests, a process for joining steel and aluminum in a double-flanged configuration is now being developed. The double flanged seams are joined using zinc- or aluminum-based filler wires. Microsections of selected seams show that it is possible to achieve good base material wetting while limiting the growth of IMCs to acceptable measures. In addition, the results of tensile tests show that high joint strengths can be achieved.

Validación de la Escala Rapid Assessment of Physical Activity (RAPA en población chilena adulta consultante en Atención Primaria

Directory of Open Access Journals (Sweden)

J. Carola Pérez

2015-01-01

Full Text Available Introducción: la práctica de actividad física es esencial para el cuidado de la salud. Se requiere contar con instrumentos que permitan medirla y monitorear los cambios en las personas que la practican. Objetivos: adaptar culturalmente el cuestionario Rapid Assessment of Physical Activity (RAPA, y estimar sus propiedades psicométricas, su validez y confiabilidad, para medir el nivel de actividad física en personas adultas consultantes en centros de atención primaria en Santiago (Chile. Materiales y métodos: el RAPA adaptado fue aplicado a 180 adultos asistentes a 5 centros de salud. Se determinó su índice de masa corporal (IMC y circunferencia de cintura (CC. Resultados: las puntuaciones en la escala RAPA se relacionaron en forma inversa y significativa con el perímetro de cintura y el IMC. Las personas categorizadas con bajo nivel de actividad física (Poco Activo y Poco Activo Regular Ligero presentan un IMC promedio más elevado y son más frecuentemente categorizados con CC alterada. La confiabilidad del instrumento fue moderada (r = 0,61; K = 0,34. Conclusiones: el RAPA en su versión en español adaptada para Chile, es un instrumento de fácil aplicación, que pese a su moderada confiabilidad, logra ser sensible al desarrollo de actividad física, que presenta una relación coherente con los parámetros antropométricos de IMC y CC sensibles a dicha actividad.

Impacto de la educación participativa en el índice de masa corporal y glicemia en individuos obesos con diabetes tipo 2

Directory of Open Access Journals (Sweden)

Cabrera-Pivaral Carlos Enrique

2004-01-01

Full Text Available La obesidad eleva el riesgo de morbilidad y mortalidad y se ha relacionado con los hábitos alimentarios y estos con la educación en salud. Esta última tiene como propósito promover la participación de los enfermos en mejorar los comportamientos humanos y estilos de vida saludables y mostrar las ventajas de la educación participativa en la modificación del Índice de Masa Corporal (IMC en el diabético obeso tipo 2. Se realizó un estudio cuasi experimental con asignación aleatoria de dos grupos de pacientes diabéticos obesos. La intervención educativa-participativa se organizó mediante el proceso de reflexión-acción. Se efectuaron mediciones del IMC basal y mensuales durante los 9 meses de la intervención educativa. Los grupos fueron controlados tomando en cuenta edad y sexo. El análisis estadístico se efectuó con el estadígrafo de t de students con diferencia de media para grupos relacionados. El grupo control logra un valor promedio de IMC basal de 33.89 ± 1.96 y al final de 33.2 ± 2.15 (t: 22.4; p: 0.16, el grupo de experimento con valor inicial de 33.63 ± 2.12 y final de 31.54 ± 1.71 (t: 11.55; p = 0.003. La intervención educativa participativa contribuye a mejorar el nivel de IMC en los diabéticos obesos 2.

Bariatric surgery: is it reasonable before the age of 16?

Science.gov (United States)

Massabki, Lilian Helena Polak; Sewaybricker, Letícia Esposito; Nakamura, Keila Hayashi; Mendes, Roberto Teixeira; Barros, Antonio DE Azevedo; Antonio, Maria Ângela Reis DE Góes Monteiro; Zambon, Mariana Porto

2016-01-01

to assess the severity of obesity in children and adolescents through the presence of comorbidities and the potential indication of bariatric surgery. we conducted a cross-sectional study with clinical and laboratory data of the first consultation of patients at the childhood obesity clinic at a tertiary hospital from 2005 to 2013. We divided the patients into groups with or without potential indication for surgery, and recorded age, gender, birth weight, age of obesity onset, BMI Z score, presence of acanthosis nigricans, blood pressure, total cholesterol and fractions, triglycerides, blood glucose and fasting insulin, HOMA1-IR, CRP and ESR. The group with potential indication for surgery included: BMI > 40 or between 35-40 with comorbidities (Triglycerides >130mg/dl, glucose levels >100mg/dl, HOMA1-IR >3.16, Total Cholesterol >200mg/dl, LDL >130mg/dl and HDL insulina de jejum, HOMA1-IR, PCR e VHS. O grupo com potencial indicação cirúrgica incluiu: IMC >40 ou IMC entre 35-40 com comorbidades (Triglicérides >130mg/dl, Glicemia >100mg/dl, HOMA1-IR >3,16, Colesterol total >200mg/dl, LDL >130mg/dl e HDL insulina, PCR, VHS, idade, escore z de IMC e pressões sistólica e diastólica foram significantes no grupo com potencial indicação cirúrgica. os resultados sugerem que a cirurgia bariátrica, poderia estar indicada pelo IMC e presença de comorbidades, em crianças e adolescentes com menos de 16 anos.

Historia de obesidad como factor asociado al cáncer de mama en pacientes de un hospital público del Perú

Directory of Open Access Journals (Sweden)

José Rojas-Camayo

2009-07-01

Full Text Available Realizamos un estudio de casos y controles, en 123 pacientes con diagnóstico de cáncer mamario (casos y 208 pacientes sanas (controles. En la medición se consideró el índice de masa corporal (IMC antiguo (peso promedio de la vida adulta de la persona e IMC actual (peso cuantificado al momento de efectuar la investigación y otros factores de riesgo conocidos. Los IMC antiguos mostraron un riesgo incrementado tanto en mujeres en la premenopausia: sobrepeso OR: 7,29 (IC95%: 1,75 - 30,38 y obesidad OR: 23,43 (IC95%: 2,4 - 229.7; como en mujeres posmenopáusicas: obesidad OR: 3,33 (IC95%: 1,54 - 7,19 y obesidad OR: 6,04 (IC95%: 1,78 - 20,50. Por otro lado, al evaluar el IMC actual, se encontró asociación en las premenopáusicas donde el sobrepeso es un factor protector OR: 0,23 (IC95%: 0,05 - 0,99 y la obesidad no muestra asociación OR: 0,37 (IC95%: 0,08 - 1,8, asimismo, en las posmenopáusicas no se evidenció asociación con el sobrepeso OR: 0,79 (IC95%:0,35 - 1,85 ni con la obesidad OR: 1,19 (IC95%: 0,42 - 3,38. Se concluye que la historia de obesidad está asociada con un incremento de riesgo de cáncer mamario tanto en mujeres premenopáusicas y posmenopáusicas.

GRASA CORPORAL E ÍNDICE ADIPOSO-MUSCULAR ESTIMADOS MEDIANTE IMPEDANCIOMETRÍA EN LA EVALUACIÓN NUTRICIONAL DE MUJERES DE 35 A 55 AÑOS

Directory of Open Access Journals (Sweden)

Vicente Martín Moreno

2002-01-01

Full Text Available Fundamentos: La evaluación nutricional durante la premenopausia y la menopausia tiene un papel relevante para valorar los cambios que acontecen en la mujer. El objetivo de este estudio es comparar los parámetros grasa corporal e índice adiposo- muscular corporal (IAMC estimados mediante impedanciometría respecto al índice de masa corporal (IMC en la definición del estado nutricional y la composición corporal. Métodos: Estudio descriptivo transversal. Mediante muestreo aleatorio (base de tarjeta sanitaria fueron seleccionadas 30 mujeres de 35 a 55 años, valorándose en ellas la asociación entre grasa corporal e IAMC con el IMC; diferentes estimadores de la distribución de la grasa corporal: circunferencias de la cintura y cresta ilíaca, cocientes cintura-cadera e ilíaca-cadera y diámetros ilíaco y sagital; presiones arteriales sistólica (PAS y diastólica (PAD y niveles plasmáticos de glucosa, colesterol, HDL-colesterol y triglicéridos. Resultados: El porcentaje de grasa corporal correlacionó intensamente (p 33% presentaba un IMC menor de 30. Conclusiones: La estimación de los parámetros grasa corporal e IAMC en mujeres de 35 a 55 años complementa la evaluación nutricional realizada mediante el IMC, aunque para definir su verdadero valor en esta evaluación es necesario establecer los parámetros de normalidad en la población.

Efeito da utilização de complemento alimentar em idosos atendidos em um ambulatório na cidade de São Paulo

OpenAIRE

Borrego, Carolina de Campos Horvat; Cantaria, Juliana dos Santos

2013-01-01

OBJETIVO: Verificar o efeito da utilização de complemento alimentar na população idosa atendida pelo setor de nutrição de um ambulatório na cidade de São Paulo, por meio da evolução do peso e do Índice de Massa Corpórea (IMC) desses pacientes. MÉTODOS: A amostra foi composta de idosos com 60 anos ou mais, de ambos os sexos, que fazem uso de complemento alimentar prescrito pelas nutricionistas do setor. As variáveis estudadas foram: gênero, idade, peso, estatura, IMC, patologias mais frequente...

A OBESIDADE NA POPULAÇÃO ADULTA DE DIAMANTINA: ORIENTAÇÕES PARA A SAÚDE, CARACTERIZAÇÃO ANTROPOMÉTRICA, BIOQUÍMICA E DE APTIDÃO CARDIORRESPIRATÓRIA

OpenAIRE

Bruna Caroline Chaves Garcia; Mariana Aguiar De Matos; Kaio César Pinhal; Marcos Felipe Andrade Oliveira; Rodrigo Teixeira Almeida; Maksilane Eudilane Bento; Vanessa Oliveira Fernandes; Flávio Castro Magalhães; Elizabethe Adriana Esteves; Etel Rocha-Vieira; Fabiano Trigueiro Amorim

2016-01-01

Resumo: Este estudo caracterizou indivíduos adultos obesos que participaram de um programa de atividades de extensão composto por orientações nutricionais no município de Diamantina-MG. Foram recrutados 42 indivíduos obesos (7 homens e 35 mulheres, índice de massa corporal [IMC] de 36,5 ± 4,3 kg m-2) com idade entre 19 e 56 anos. Todos os voluntários foram submetidos à avaliação do IMC, circunferência da cintura (CC) e percentual de gordura, glicemia e insulinemia de jejum, teste de tolerânci...

Distributed Generation using Indirect Matrix Converter in Boost Operating Mode

DEFF Research Database (Denmark)

Liu, Xiong; Loh, Poh Chiang; Wang, Peng

2011-01-01

, reverse power flow operation of IMC can be implemented to meet voltage boost requirement, where the input ac source is connected to the converter's voltage source side and the output utility grid or load is connected to the current source side. This paper proposes control schemes of IMC under reverse...... power flow operation for both grid-connected and isolated modes with distributed generation suggested as a potential application. In grid-connected mode, the commanded power must be extracted from the input ac source to the grid, in addition to guarantee sinusoidal input/output waveforms, unity input...

A anorexia nervosa e fatores associados em adolescentes do sexo feminino, em município do sul do Brasil

OpenAIRE

Hulsmeyer, Ana Rodrigues; Marcon, Sonia Silva; Santana, Rosângela Getirana; Kállas, Daniel

2011-01-01

Objetivo foi investigar a prevalência de sintomas de anorexia nervosa e a sua associação com o Índice de Massa Corporal (IMC), e com satisfação e dimensão corporais, em adolescentes do sexo feminino. Trata-se de um estudo de base populacional, do tipo transversal, realizado com 407 adolescentes entre 14 e 19 anos, e incluiu a avaliação do IMC, o Eating Attitude Test, e a Escala de Silhuetas Corporais. A associação entre as variáveis dependente e independente foi realizada por meio da análise ...

Quando o desejo se submete à necessidade de comer… : Características do comportamento alimentar numa amostra de mulheres com obesidade

OpenAIRE

Leitão, Mafalda Rodrigues

2011-01-01

Dissertação de Mestrado apresentada ao ISPA - Instituto Universitário O presente estudo pretende averiguar, numa amostra de 70 mulheres com um Índice de Massa Corporal (IMC) superior a 30kg/m², os comportamentos alimentares, nomeadamente à ingestão emocional, ingestão externa e restrição alimentar, avaliados pelo Questionário Holandês do Comportamento Alimentar (Q.H.C.A.). Pretende ainda explorar a associação do IMC e à existência ou não de um problema psicológico. Além disso, ...

Efeitos do consumo de amendoim com diferentes teores de ácido graxo oléico na permeabilidade intestinal e endotoxemia em homens com excesso de peso

OpenAIRE

Moreira, Ana Paula Boroni

2013-01-01

O consumo de amendoim tem sido relacionado a inúmeros benefícios à saúde. A frequência de consumo de amendoim tem se associado inversamente ao índice de massa corporal (IMC) e risco de obesidade. O objetivo deste estudo foi avaliar os efeitos do consumo de uma dieta hipocalórica contendo ou não amendoim na permeabilidade intestinal e na concentração de lipopolissacarídeo (LPS) plasmático. Homens com excesso de peso (IMC entre 26-35 kg/m2) e idade entre 18-50 anos foram aleatoriamente alocados...

Comportamientos alimentarios cotidianos y anómalos en una muestra comunitaria de adultos chilenos

OpenAIRE

Oda Montecinos, Camila; Saldaña García, Carmina; Andrés, Ana

2015-01-01

Objetivos: Caracterizar el comportamiento alimentario cotidiano de una muestra de población adulta chilena, en función del Índice de Masa Corporal (IMC) y el género de los participantes, así como analizar la posible relación de estas variables con comportamientos alimentarios anómalos. Métodos: 657 participantes (437 mujeres y 220 hombres de 18 a 64 años) fueron evaluados con una batería de cuestionarios autoadministrados. El IMC promedio fue 25,50 kg/m2 (24,96 kg/m2 mujeres y 26,58 kg/m2 hom...

Calorimetric investigation into interaction in Zr0.8Ti0.2CrFe-H2 system

International Nuclear Information System (INIS)

Sirotina, R.A.; Verbetskij, V.N.

1993-01-01

For studying Zr 0.8 Ti 0.2 CrFe-H 2 system is applied the calorimetric method with usage of the Tian-Calve type calorimeter. It is shown that up to 488 K in the system there are three characteristic regions: α (hydrogen solution in an intermetallic compounds (IMC)), β (hydrogen solution in a hydride) and α + β (region of coexistence of two phases). Temperature 448 K is near to critical one, when exceeding of which exists only hydrogen solution in a metal matrix. Pressure dependence of hydrogen content in IMC is described satisfactorily by a linear equation

Perfil antropométrico e adiposidade abdominal de escolares entre 6 a 10 anos de idade do Sul do Brasil

Directory of Open Access Journals (Sweden)

Gabriela Dalsasso Ricardo

2012-10-01

Full Text Available http://dx.doi.org/10.5007/1980-0037.2012v14n6p636 O estudo teve como objetivo avaliar a associação de medidas antropométricas com o Índice de Massa Corporal (IMC e verificar a presença de adiposidade abdominal em escolares. Estudo transversal realizado entre 2007-2008, com 4.964 escolares de 6 a 10 anos de idade, matriculados em 345 escolas de oito municípios do Estado de Santa Catarina. As variáveis independentes utilizadas foram: dobras cutâneas subescapular (DCS e tricipital (DCT, circunferências do braço (CBr, cintura (CC e quadril (CQ e relações cintura/quadril (RCQ e cintura/estatura (RCEst. O IMC foi utilizado como variável dependente. Associações brutas e ajustadas foram estimadas mediante regressão linear e expressados como coeficiente de regressão (β. Para análise ajustada, todas as medidas antropométricas foram controladas entre si, mantendo-se no modelo aquelas com p<0,20. Classificou-se a adiposidade abdominal com a RCEst ≥ 0.5. Os resultados mostram que o IMC médio dos meninos foi 17,4kg/m2 (DP=2,8 e das meninas 17,2kg/ m2 (DP=2,8. As médias das medidas antropométricas para os sexos masculino e fe­minino foram, respectivamente: DCS=7,2 e 8,3mm; DCT=10,8 e 12,6mm; CBr=20,0 e 20,2cm; CC=60,1 e 58,5cm; CQ=71,3 e 71,9cm; RCQ=0,84 e 0,81; RCEst=0,45 e 0,44. Todas as medidas antropométricas se associaram positivamente com o IMC na análise bruta, para ambos os sexos. Na análise ajustada, nos meninos, mantiveram-se associadas: DCS (β=0,05, CBr (β=0,17, CC (β=0,19 e RCEst (β=30,5. Nas meninas, continuaram associadas a DCS (β=0,19, CBr (β=0,17, CC (β=0,13, RCQ (β=-6,2 e RCEst (β=32,1. Apresentaram adiposidade abdominal 11,9% (n=589 dos escolares, de acordo com a RCEst. Pode-se concluir que os indicadores DCS, CBr, CC e RCEst apresentaram boa relação com o IMC em escolares de ambos os sexos. Estas medidas poderiam ser utilizadas como complemento ao IMC para determinação da adiposidade corporal total e

Insatisfação com o peso e a massa corporal em estudantes do ensino fundamental e médio do sexo feminino no município do Rio de Janeiro Insatisfacción com el peso y masa corporal entre los estudiantes de la escuela primaria y secundaria del sexo femenino em la ciudad de Rio de Janeiro Dissatisfaction with mass and body weight among elementary and high school female students in the city of Rio de Janeiro

Directory of Open Access Journals (Sweden)

Alexandre Palma

2013-03-01

Full Text Available O objetivo do presente estudo foi verificar a prevalência de insatisfação corporal entre adolescentes do sexo feminino na cidade do Rio de Janeiro. Foram investigadas 2.149 estudantes do sexo feminino, entre 14 e 18 anos de idade. Foram aferidos os pesos, estaturas e índices de massa corporal (IMC informados e desejados. A insatisfação corporal foi considerada de dois modos: a através do desejo de modificar o IMC; e, b o desejo de alterar o peso corporal em valor superior a 10% do peso informado. Do total investigado, 93,58% expressaram o desejo de modificar o IMC. Foi possível observar, ainda, que 42,48% manifestaram insatisfação com o peso. É possível concluir, então, que as adolescentes investigadas manifestaram tendência à insatisfação com o peso corporal.El objetivo del presente estudio fue determinar la prevalencia de la insatisfacción corporal en adolescentes del sexo femenino en la ciudad de Río de Janeiro. Se investigaron 2.149 estudiantes con edades comprendidas entre 14 y 18 años. Se levantaron los pesos, las alturas y los índices de masa corporal (IMC informados y deseados. La insatisfacción con el cuerpo fue considerada de dos maneras: a por el deseo de cambiar el IMC y b el deseo de cambiar el peso (en kg con valores superiores a los 10% del peso informado. Del total, 93,58% expresó el deseo de cambiar su IMC. También observamos que 42,48% reportaron insatisfacción con el peso. Es posible concluir que las adolescentes encuestadas expresaron una tendencia de insatisfacción con su peso corporal.The aim of this study was to verify the prevalence of body dissatisfaction among adolescent girls in the city of Rio de Janeiro. 2,149 female students aged between 14 and 18 years were investigated. Informed and desired weights, heights and the body mass index (BMI were also investigated. The body dissatisfaction was addressed in two ways: a by the desire to change the BMI and b the desire to change the weight (in kg

Determinantes do índice de massa corporal em adolescentes de escolas públicas de Piracicaba, São Paulo Determining of body mass index in adolescents from public schools in Piracicaba, São Paulo State

Directory of Open Access Journals (Sweden)

Alexandre Romero

2010-01-01

Full Text Available O objetivo do presente estudo foi verificar os fatores determinantes do índice de massa corporal (IMC de adolescentes matriculados nas escolas públicas de Piracicaba, São Paulo. A amostra foi constituída por 328 adolescentes de ambos os sexos, com idade mínima de dez anos. Verificou-se peso, estatura, maturação sexual, atividade física e consumo alimentar. Foi usado um modelo de regressão linear múltipla para verificar a associação entre as variáveis independentes e o IMC. Enquanto as meninas consideradas fisicamente ativas apresentaram maior média de IMC do que as insuficientemente ativas, a média do IMC dos meninos não apresentou diferença estatística quando comparada entre meninos ativos e insuficientemente ativos. A maturação sexual foi determinante do IMC, para ambos os sexos, reforçando a ideia de que é fundamental levar em consideração essa variável em estudos que avaliam o estado nutricional em adolescentes. Acredita-se que os métodos utilizados no presente estudo, os quais são normalmente utilizados em pesquisas semelhantes, apresentaram importantes limitações para avaliar a influência do nível de atividade física e do consumo alimentar sobre o IMC dos adolescentes. Dessa forma, ressalta-se a necessidade de aprimoramento desses métodos para adoção em futuros estudos.The objective of this study was to assess determining factors of body mass index (BMI in adolescents enrolled in public schools in Piracicaba, São Paulo. The sample had 328 adolescents from both genders; minimum age was 10 years old. We have assessed weight, height, sexual maturity, physical activity, and diet. A multiple linear regression model was used to assess the association between independent variables and BMI. While girls considered physically active presented greater mean BMI than those insufficiently active, boys did not present statistical difference between mean BMI among those active and those insufficiently active. Sexual

Sustainable biotechnology: sources of renewable energy

National Research Council Canada - National Science Library

Singh, Om V; Harvey, Steven P

2010-01-01

... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Anuj K. Chandel, Om V. Singh, and L.Venkateswar Rao 63 Tactical Garbage to Energy Refinery (TGER) . . . . . . . . . . . . . . . James J. Valdes and Jerry B. Warner...

Limitaciones del IMC como indicador exclusivo de estado nutricional

OpenAIRE

Moreno Romero, Susana; Dipierri, José Edgardo; Marrodán, María D.

2007-01-01

El presente trabajo tiene como objetivo determinar el potencial diagnóstico y las limitaciones del uso del Índice de Masa Corporal como único indicador del estado nutricional. Para ello se analizó una muestra constituida por 2155 sujetos de ambos sexos, con edades comprendidas entre los 6 y 18 años y pertenecientes a tres poblaciones jujeñas que difieren en ubicación altitudinal y nivel socieconómico (NSE): 1.) Susques, localidad rural situada a 3675 m.s.n.m; 2.) Alto Comedero, barrio perifér...

Thrombophilic screening in retinal artery occlusion patients

Directory of Open Access Journals (Sweden)

Valeria Nagy

2008-10-01

Full Text Available Valeria Nagy1, Lili Takacs1, Zita Steiber1, György Pfliegler2, Andras Berta11Department of Ophthalmology, 2Division of Rare Diseases, University of Debrecen Medical and Health Science Center, Debrecen, HungaryBackground: Retinal artery occlusion (RAO is an ischemic vascular damage of the retina, which frequently leads to sudden, mostly irreversible loss of vision. In this study, blood thrombophilic factors as well as cardiovascular risk factors were investigated for their relevance to this pathology. Thrombophilic risk factors so far not evaluated were included in the study.Patients and methods: 28 RAO patients and 81 matched control subjects were examined. From blood samples, protein C, protein S, antithrombinopathy, and factor V (Leiden mutation (FV, factor II gene polymorphism, factor VIII C level, plasminogen activity, lipoprotein(a and fibrinogen levels, hyperhomocysteinemia and presence of anticardiolipin – antiphospholipid antibodies were investigated. Possibly relevant pathologies such as diabetes mellitus, hypertension, and ischemic heart disease were also registered. Statistical analysis by logistic regression was performed with 95% confidence intervals.Results: In the group of patients with RAO only the incidence of hypertension (OR: 3.33, 95% CI: 1.30–9.70, p = 0.014 as an average risk factor showed significant difference, but thrombophilic factors such as hyperfibrinogenemia (OR: 2.9, 95% CI: 1.29–6.57, p = 0.010 and the presence of FV (Leiden mutation (OR: 3.9, 95% CI: 1.43–10.96, p = 0.008 increased the chances of developing this disease.Conclusions: Our results support the assumption that thrombophilia may contribute to the development of RAO besides vascular damage due to the presence of cardiovascular risk factors. Further studies are needed, however, to justify the possible use of secondary prophylaxis in form of anticoagulant/antiplatelet therapy.Keywords: retinal arterial occlusion, risk factors, thrombophilia

Generalized functional linear models for gene-based case-control association studies.

Science.gov (United States)

Fan, Ruzong; Wang, Yifan; Mills, James L; Carter, Tonia C; Lobach, Iryna; Wilson, Alexander F; Bailey-Wilson, Joan E; Weeks, Daniel E; Xiong, Momiao

2014-11-01

By using functional data analysis techniques, we developed generalized functional linear models for testing association between a dichotomous trait and multiple genetic variants in a genetic region while adjusting for covariates. Both fixed and mixed effect models are developed and compared. Extensive simulations show that Rao's efficient score tests of the fixed effect models are very conservative since they generate lower type I errors than nominal levels, and global tests of the mixed effect models generate accurate type I errors. Furthermore, we found that the Rao's efficient score test statistics of the fixed effect models have higher power than the sequence kernel association test (SKAT) and its optimal unified version (SKAT-O) in most cases when the causal variants are both rare and common. When the causal variants are all rare (i.e., minor allele frequencies less than 0.03), the Rao's efficient score test statistics and the global tests have similar or slightly lower power than SKAT and SKAT-O. In practice, it is not known whether rare variants or common variants in a gene region are disease related. All we can assume is that a combination of rare and common variants influences disease susceptibility. Thus, the improved performance of our models when the causal variants are both rare and common shows that the proposed models can be very useful in dissecting complex traits. We compare the performance of our methods with SKAT and SKAT-O on real neural tube defects and Hirschsprung's disease datasets. The Rao's efficient score test statistics and the global tests are more sensitive than SKAT and SKAT-O in the real data analysis. Our methods can be used in either gene-disease genome-wide/exome-wide association studies or candidate gene analyses. © 2014 WILEY PERIODICALS, INC.

Índice de masa corporal y percepción de la imagen corporal en estudiantes de enfermería Body Mass Index and perception of corporal image in nursing students

Directory of Open Access Journals (Sweden)

Gloria Alcaraz López

2011-06-01

Full Text Available Objetivo. Analizar la relación entre el índice de masa corporal (IMC y la percepción de la imagen corporal. Metodología. A 199 estudiantes de enfermería, Universidad de Antioquia, 2007, se calculó el IMC y la imagen corporal utilizando la escala de siluetas propuesta por Sorensen et al. Se utilizaron las medidas de tendencia central, dispersión y proporciones. Se evaluó el nivel de concordancia entre el IMC real y la percepción de la imagen corporal y el nivel de concordancia de estas dos variables con la edad y con el semestre académico que cursaban. Resultados. Edad promedio 23,3 años, IMC de 22,7, 68,4% sobreestiman su imagen corporal (p= 0,05 y 4,5% la subestiman. Hubo concordancia entre el IMC real y la percepción de la imagen corporal sólo en 38,2%. Conclusión. La sobreestimación de la imagen corporal podría afectar el modelo de atención de enfermería y por ende alterar en los pacientes su autopercepción y estado nutricional.Objective. To explore the relationship between Body Mass Index (BMI and body image's perception. Methodology. BMI and body image silhouettes from 199 Universidad de Antioquia's female students, from Medellin - Colombia, 2007 Body image's perception were calculated using the Sorensen et al's scale. We used measures of central tendency, dispersion, and proportion, besides, we measured the level of agreement between actual BMI and body image perception and level of agreement of these two variables with age and undergraduate level. Results. Average age 23.3 years, BMI 22.7 (SD: 2.9, 68.4% overestimated their body image (p = 0.05 and 4.5% underestimated it. There was concordance between actual BMI and body image perception in only 38.2%. Conclusion. This overestimation of body image's perception might affect the care model assistance that nurses provide to their patients and consequently it might distortion patients self perception and nutritional status.

Growth performance, meat quality traits, and genetic mapping of quantitative trait loci in 3 generations of Japanese quail populations (Coturnix japonica).

Science.gov (United States)

Tavaniello, S; Maiorano, G; Siwek, M; Knaga, S; Witkowski, A; Di Memmo, D; Bednarczyk, M

2014-08-01

The current research was conducted to compare growth, carcass traits, pH, intramuscular collagen (IMC) properties, and genetic bases of IMC and carcasses (breast-muscle weight) of different lines and generations of adult males and females of Japanese quail (Coturnix japonica). Forty-four quails (generation F0), 22 Pharaoh (F-33) meat-type males and 22 Standard (S-22) laying-type females, were crossed to produce the F1 hybrids generation. The F2 generation was created by mating one F1 male with one F1 female, full siblings. The birds, randomly chosen from F0 (22 males and 22 females), F1 (22 males and 22 females), and F2 (84 males and 152 females) were raised to 20 wk of age in collective cages. Quails were fed ad libitum commercial diets. At slaughter, all birds were individually weighed (after a fasting period of 12 h) and dressing yield (without giblets) was calculated. The carcasses were then dissected. Genomic DNA was extracted from all of the blood, and 30 microsatellite markers located on 2 quail chromosomes were genotyped. The F -: 33 quails had higher in vivo and postmortem performances and a higher abdominal fat percentage than those of the egg line. Meat from S -: 22 quails had a slower collagen maturation (hydroxylysylpyridinoline crosslink/collagen) and a higher ultimate pH. The F1 and F2 generations showed an evident sexual dimorphism, and an additional effect could be due to hybrid heterosis evident in F2. Meat from quails of F1 and F2 generations had a lower IMC amount with a higher degree of collagen maturation compared with parental lines. Two statistically significant QTL have been detected on quail chromosome 2 (CJA02): a QTL with an additive effect (0.50) for IMC in the marker bracket GUJ0037 and GUJ0093; a second QTL with additive (1.32) and dominant (1.91) effects for breast-muscle weight in the marker bracket GUJ0084 and GUJ0073. To our knowledge, this is the first report of a QTL associated with breast-muscle weight and IMC in quail and

Niveles de presión arterial, circunferencia abdominal y sobrepeso/obesidad en los estudiantes universitarios de la Universidad Peruana Unión – Tarapoto

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Saulo Salinas

2014-11-01

Full Text Available El sobrepeso y la obesidad aumentan el riesgo de padecer enfermedades cardiovasculares y otras patologías que alteran significativamente la calidad y expectativa de vida. Estudios en otras poblaciones de América Latina y el Perú muestran que la prevalencia de obesidad viene aumentando en las últimas décadas, por otro lado la presión arterial es un indicador importante para conocer el desenvolvimiento del trabajo constante del corazón. Se desarrolló el estudio con 132 estudiantes distribuidos en las diferentes facultades, 82 mujeres y 50 varones. Las variables consideradas fueron Índice de Masa Corporal (IMC, Circunferencia Abdominal (CA, Presión Arterial Sistólica (PAS y diastólica (PAD. Se analizaron los datos mediante el software estadístico SPSS (20.0. Se realizó un análisis descriptivo de medias y desviación estándar de las variables, posteriormente se aplicó el Test de Kolmogorov – Smirnov y correlación de Pearson para IMC y CA. Entre los resultados se encontró que las medias del IMC fue de 22.3 ± 2.6 y CA de 77.9 ±6.4 dentro de los parámetros normales con diferencias mínimas entre géneros, asimismo la PAS y PAD fue de 96.9 ± 7.3- 58 ± 7.2 manteniendo las diferencias. La prueba de normalidad indicó que la distribución de los datos en cada género eran normales (p=0.2 con un nivel de significancia de 0.01. La correlación de Pearson r = 0.7 indica que las variables IMC y CA están asociadas positivamente con p = 0.0. Se concluye que los varones están expuestos a presentar PAS y PAD, mayores a los del género opuesto, asimismo el sobrepeso obtuvo el 12.9% de los estudiantes evaluados y que al evaluar el IMC, las mujeres presentan superioridad mínima que los varones. Estos datos demuestran que la obesidad puede ser progresiva si no se toman las precauciones necesarias

Grasa corporal e índice adiposo-muscular estimados mediante impedanciometría en la evaluación nutricional de mujeres de 35 a 55 años

Directory of Open Access Journals (Sweden)

Martín Moreno Vicente

2002-01-01

Full Text Available Fundamentos: La evaluación nutricional durante la premenopausia y la menopausia tiene un papel relevante para valorar los cambios que acontecen en la mujer. El objetivo de este estudio es comparar los parámetros grasa corporal e índice adiposo-muscular corporal (IAMC estimados mediante impedanciometría respecto al índice de masa corporal (IMC en la definición del estado nutricional y la composición corporal. Métodos: Estudio descriptivo transversal. Mediante muestreo aleatorio (base de tarjeta sanitaria fueron seleccionadas 30 mujeres de 35 a 55 años, valorándose en ellas la asociación entre grasa corporal e IAMC con el IMC; diferentes estimadores de la distribución de la grasa corporal: circunferencias de la cintura y cresta ilíaca, cocientes cintura-cadera e ilíaca-cadera y diámetros ilíaco y sagital; presiones arteriales sistólica (PAS y diastólica (PAD y niveles plasmáticos de glucosa, colesterol, HDL-colesterol y triglicéridos. Resultados: El porcentaje de grasa corporal correlacionó intensamente (p<0,001 con IMC (r=0,919, circunferencias de la cintura (r=0,866 e ilíaca (r=0,841 y diámetros sagital (r=0,783 e ilíaco (r=0,772, y, menos intensamente, con la glucemia (r=0,385; p=0,036 y la PAS (r=0,497; p=0,005 y PAD (r=0,582; p=0,001. El IAMC presentó similares resultados, sin asociarse significativamente con ningún parámetro bioquímico. El 46,7% de las mujeres obesas según su porcentaje de grasa corporal (33% presentaba un IMC menor de 30. Conclusiones: La estimación de los parámetros grasa corporal e IAMC en mujeres de 35 a 55 años complementa la evaluación nutricional realizada mediante el IMC, aunque para definir su verdadero valor en esta evaluación es necesario establecer los parámetros de normalidad en la población.

Role of performance measures in reengineering U.S. Department of Energy's management of environmental management programs

International Nuclear Information System (INIS)

Murthy, K.S.; Harroun, W.P.

1996-01-01

The Rocky Flats Environmental Technology Site (Rocky Flats) contributed to America's defense up to the end of the Cold War. It is one of several large US Department of Energy (DOE) nuclear industrial facilities, currently undergoing cleanup and closure. The Site was constructed in a sparsely populated area along the Rocky Mountain Foothills, near Denver, in 1952. In the 45 years since, Denver has grown to a major metropolitan area. Over 2 million people live within the Site's 50-mile radius. The Site is directly upstream of water supplies that serve over 300,000 people. As a result, accelerated cleanup, consolidation, reuse, and closure of the Site are the current essentials. The Site has had three management and operating (M and O) contractors since inception. In keeping with the shift in the Site's paradigm from one of weapon-parts production program to cleanup and closure project, DOE changed its contracting philosophy for the Site from the M and O type of contract to a Performance-based Incentive Fee Integrating Management contract (PBIF IMC). Doe selected the Site's fourth contractor as an IMC contractor in July 1995. Kaiser-Hill Company L.L.C. was awarded the contract and assumed IMC responsibility for the Site on July 1, 1995. Integral to this contract is the establishment and implementation of a performance measures system. Performance measures are the bases for incentives that motivate the IMC and the subcontractors working at Rocky Flats. This paper provides an overview of Performance Measures system practiced at Rocky Flats from July 1995 to December 1995. Also described are the developments in reengineering during the July 1995--March 1996 interval

Effects of Metallic Nanoparticles on Interfacial Intermetallic Compounds in Tin-Based Solders for Microelectronic Packaging

Science.gov (United States)

Haseeb, A. S. M. A.; Arafat, M. M.; Tay, S. L.; Leong, Y. M.

2017-10-01

Tin (Sn)-based solders have established themselves as the main alternative to the traditional lead (Pb)-based solders in many applications. However, the reliability of the Sn-based solders continues to be a concern. In order to make Sn-based solders microstructurally more stable and hence more reliable, researchers are showing great interest in investigating the effects of the incorporation of different nanoparticles into them. This paper gives an overview of the influence of metallic nanoparticles on the characteristics of interfacial intermetallic compounds (IMCs) in Sn-based solder joints on copper substrates during reflow and thermal aging. Nanocomposite solders were prepared by mechanically blending nanoparticles of nickel (Ni), cobalt (Co), zinc (Zn), molybdenum (Mo), manganese (Mn) and titanium (Ti) with Sn-3.8Ag-0.7Cu and Sn-3.5Ag solder pastes. The composite solders were then reflowed and their wetting characteristics and interfacial microstructural evolution were investigated. Through the paste mixing route, Ni, Co, Zn and Mo nanoparticles alter the morphology and thickness of the IMCs in beneficial ways for the performance of solder joints. The thickness of Cu3Sn IMC is decreased with the addition of Ni, Co and Zn nanoparticles. The thickness of total IMC layer is decreased with the addition of Zn and Mo nanoparticles in the solder. The metallic nanoparticles can be divided into two groups. Ni, Co, and Zn nanoparticles undergo reactive dissolution during solder reflow, causing in situ alloying and therefore offering an alternative route of alloy additions to solders. Mo nanoparticles remain intact during reflow and impart their influence as discrete particles. Mechanisms of interactions between different types of metallic nanoparticles and solder are discussed.

Sobrepeso y obesidad en una población Wichi del oeste formoseño: prevalencia y efectos bioculturales

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Lanza, Norberto

2005-01-01

Full Text Available La prevalencia sobrepeso y obesidad ha estado aumentando significativamente en los últimos años, aún en poblaciones socioeconómicamente carenciadas. Las poblaciones indígenas parecen ser particularmente susceptibles a este factor de riesgo, aunque las razones para esto no son claras. El objetivo de este trabajo fue el de analizar la prevalencia de sobrepeso y obesidad en una población rural Wichí del oeste de la provincia de Formosa. Se tomaron medidas de peso y talla en 109 mujeres y 58 varones mayores de 12 años, estimándose el índice de masa corporal (IMC. Nuestros resultados muestran una alta prevalencia de sobrepeso y obesidad en esta población: 36% de las mujeres y 29% de los hombres tenían sobrepeso, mientras que 5% de las mujeres y 7% de los hombres eran obesos. También se encontró una asociación significativa entre el IMC y la edad. La ausencia de diferencias significativas en el IMC entre sexos resulta notable ya que son las mujeres las que constitucionalmente tienden a tener mayores valores de IMC. Se hipotetiza que, debido a la intervención de factores bioculturales, los hombres tienen un mayor acceso a alimentos que las mujeres. Estos resultados y otros obtenidos por nuestro equipo en comunidades Toba, contribuyen a un mejor entendimiento de los factores de riesgo sanitario en estas poblaciones y facilitan la aplicación de políticas de salud pública culturalmente más sensibles y, por lo tanto, más efectivas.

Estilo de vida e índice de masa corporal de una población de adultos del sur de Tamaulipas, México

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Eunice Reséndiz

2010-01-01

Full Text Available La obesidad es una enfermedad multifactorial que involucra aspectos genéticos y ambientales. Objetivo: valorar la influencia del estilo de vida en el índice de masa corporal de una población de adultos. Método: este estudio descriptivo transversal se deriva del proyecto "Hábitos alimentarios y composición corporal (IMC de adultos con sobrepeso y obesidad"; cuya fase de recolección se realizó entre enero y julio de 2009; preliminarmente se presentan resultados relativos al estilo de vida. Se aplicó una cédula de datos personales y se realizaron mediciones antropométricas. Para el análisis estadístico se utilizaron medidas de tendencia central y se construyeron modelos de regresión lineal múltiple. Resultados: las mayores proporciones tanto del grupo de hombres como del de mujeres, señalaron no fumar, ni realizar algún deporte o ejercicio. En el caso del consumo de alcohol, la mayor proporción del grupo de hombres dijo consumirlo. Los modelos de regresión mostraron que en el total del grupo, así como en el grupo de mujeres, las variables tabaco y ejercicio influyeron en el IMC de los participantes, ya que tuvieron efecto en el modelo de regresión. Dichas variables se correlacionaron significativa e inversamente con el IMC, lo que particularmente llamó la atención en el caso del tabaco. Discusión: el estudio muestra que el estilo de vida influye de manera importante en el IMC de esta población de adultos.

PA/SA for Slovenian LILW repository

International Nuclear Information System (INIS)

Zeleznik, N.; Mele, I.

1999-01-01

The RAO Agency started with a new site selection procedure in 1996. As part of the preparational work for the new disposal facility, tools for assessment of the specific disposal concept influence on the environment and human has to be developed. Therefore the Slovenian assessment team that has been organized, joined the IAEAs ISAM programme, in which different approaches to performance and safety assessment were applied to safety cases. As part of the ISAM individual (national) safety cases. The RAO Agency, together with other Slovenian Inst.ions, performed the preliminary performance assessment of the Slovenian LILW repository for generic site location. The method and the results of the safety case are presented in this paper.(author)

Development of heat resistant Pb-free joints by TLPS process of Ag and Sn-Bi-Ag alloy powders

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Ohnuma I.

2012-01-01

Full Text Available TLPS (Transient Liquid Phase Sintering process is a candidate method of heat-resistant bonding, which makes use of the reaction between low-melting temperature powder of Sn-Bi base alloys and reactive powder of Ag. During heat treatment above the melting temperature of a Sn-Bi base alloy, the molten Sn-Bi reacts rapidly with solid Ag particles, which results in the formation of heat-resistant intermetallic compound (IMC. In this study, the TLPS properties between Sn-17Bi-1Ag (at.% powder with its liquidus temperature of 200°C and pure Ag powder were investigated. During differential scanning calorimetry (DSC measurement, an exothermic reaction and an endothermic reaction occurred, which correspond to the formation of the e-Ag3Sn IMC phase and the melting of the Sn-17Bi-1Ag alloy, respectively. After the overall measurement, the obtained reactant consists of the Ag3Sn-IMC and Bi-rich phases, both of which start melting above 250°C, with a small amount of the residual Sn-Bi eutectic phase. These results suggest that the TLPS process can be applied for Pb-free heatresistant bonding.

Application of chitosan and its N-heterocyclic derivatives for preconcentration of noble metal ions and their determination using atomic absorption spectrometry.

Science.gov (United States)

Azarova, Yu A; Pestov, A V; Ustinov, A Yu; Bratskaya, S Yu

2015-12-10

Chitosan and its N-heterocyclic derivatives N-2-(2-pyridyl)ethylchitosan (2-PEC), N-2-(4-pyridyl) ethylchitosan (4-PEC), and N-(5-methyl-4-imidazolyl) methylchitosan (IMC) have been applied in group preconcentration of gold, platinum, and palladium for subsequent determination by atomic absorption spectroscopy (AAS) in solutions with high background concentrations of iron and sodium ions. It has been shown that the sorption mechanism, which was elucidated by XPS, significantly influences the sorption capacity of materials, the efficiency of metal ions elution after preconcentration, and, as a result, the accuracy of metal determination by AAS. We have shown that native chitosan was not suitable for preconcentration of Au(III), if the elution step was used as a part of the analysis scheme. The group preconcentration of Au(III), Pd(II), and Pt(IV) with subsequent quantitative elution using 0.1M HCl/1M thiourea solution was possible only on IMC and 4-PEC. Application of IMC for analysis of the national standard quartz ore sample proved that gold could be accurately determined after preconcentration/elution with the recovery above 80%. Copyright © 2015 Elsevier Ltd. All rights reserved.

Study of the usefulness on liver CT using intermittent bolus injection method

International Nuclear Information System (INIS)

Hayashi, Hideo

1990-01-01

Usefulness on the liver CT using intermittent bolus injection method of contrast media (IM-CE) was studied in 108 hepatic space occupying lesions, particularly to analyze hepatocellular carcinoma (HCC). Scans were obtained before, 20∼30 (arterial phase) and 60 seconds (parenchymal phase) after intravenous bolus injection of 65%-diatrizoate (angiografin) or 300 mg I-iopamidol (iopamiron 300), and in case of necessity, added 3∼15 minutes (late phase) after all injections of contrast media. These scans imaging the features of hepatic mass provided us much useful information. Early enhancement of the arterial phase, and early wash out of the parenchymal phase and delayed ring enhancement of the capsule improved the rates of detection to 96%, 60%, and 49% respectively in case of HCC. Especially. at the small HCC (less than 2cm in diameter), these rates were 89%, 50%, and 28% respectively. Combination of these 3 findings suggested the possibility of HCC in comparison with other hepatic mass. The rate of accurate diagnosis of HCC by this IM-CE was 81%. Thus IM-CE CT provides the useful information in diagnosis of hepatic mass and should be considered as the routine examination of hepatic mass. (author)

Control of Neutralization Process Using Soft Computing

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G. Balasubramanian

2008-03-01

Full Text Available A novel model-based nonlinear control strategy is proposed using an experimental pH neutralization process. The control strategy involves a non linear neural network (NN model, in the context of internal model control (IMC. When integrated into the internal model control scheme, the resulting controller is shown to have favorable practical implications as well as superior performance. The designed model based online IMC controller was implemented to a laboratory scaled pH process in real time using dSPACE 1104 interface card. The responses of pH and acid flow rate shows good tracking for both the set point and load chances over the entire nonlinear region.

Anxiety and depression symptoms in women with and without binge eating disorder enrolled in weight loss programs Sintomas de ansiedade e depressão em mulheres com e sem compulsão alimentar participantes de programas de redução de peso

OpenAIRE

Simone Armentano Bittencourt; Paola Lucena-Santos; João Feliz Duarte Moraes; Margareth da Silva Oliveira

2012-01-01

Objetivos: 1) Investigar a associação entre escores de compul¬são alimentar, sintomas de ansiedade e de depressão e índice de massa corporal (IMC); e 2) verificar se existe diferença na inten¬sidade dos sintomas de ansiedade, dos sintomas depressivos e no IMC em mulheres com e sem compulsão alimentar. Método: A amostra foi composta de 113 mulheres com idade entre 22 e 60 anos (39,35±10,85), participantes de programas de redução de peso na cidade de Porto Alegre, sul do Brasil. Foram aplicados...

Gender, sexuality, and HIV/AIDS: the what, the why, and the how.

Science.gov (United States)

Gupta, G R

2000-01-01

The focus of Geeta Rao Gupta's plenary presentation of 12 July 2000 at the XIII International AIDS Conference is on the what, why, and how of gender, sexuality, and HIV/AIDS. Dr Rao Gupta discusses the factors associated with women's vulnerability to HIV; and the ways in which unequal power balance in gender relations increases not only women's, but also men's, vulnerability to HIV-despite, or rather because of, their greater power. She then addresses the question of how one is to overcome the seemingly insurmountable barriers of gender and sexual inequality. How can we change the cultural norms that create damaging, even fatal, gender disparities and roles? According to Dr Rao Gupta, an important first step is to recognize, understand, and publicly discuss the ways in which the power imbalance in gender and sexuality fuels the epidemic. She provides examples of sensitive, transformative, and empowering approaches to gender and sexuality and concludes that, in the final analysis, reducing the imbalance in power between women and men requires policies that are designed to empower women--policies that aim to decrease the gender gap in education, improve women's access to economic resources, increase women's political participation, and protect women from violence.

Analisa Greenwater Akibat Gerakan Offshore Security Vessel

Directory of Open Access Journals (Sweden)

Maulidya Octaviani Bustamin

2012-09-01

Full Text Available Analisa  Tugas  Akhir  ini,  terdiri  atas  beberapa  tahapan.  Yang pertama yaitu perancangan struktur Offshore Security Vessel (OSV dengan bantuan software MAXSURF guna mendapatkan Lines Plan. Offset data yang diperoleh digunakan dalam pemodelan menggunakan MOSES,  kemudian  dilakukan  analisa  gerak  OSV  dalam  gelombang  regular  dan dinyatakan dalam grafik RAO. Analisa gerak relatif vertikal  haluan dihitung dari RAO gerakan, dan kemudian melakukan evaluasi perilaku di gelombang acak dengan analisis spektra gelombang. Dari analisa spektra didapatkan parameter greenwater sehingga dapat dihitung peluang, intensitas dan tekanan greenwater. Dari hasil analisa diperoleh RAO gerak vertikal Offshore Security Vessel (OSV pada  gelombang  reguler yang dipengaruhi  oleh  kecepatan,  kondisi  muatan  dan arah gelombang. Peluang terjadinya greenwater terbesar terjadi pada sudut datang gelombang following sea (0o dimana harga terbesar terjadi pada ω = 0.2 rad/sec dengan periode 29 detik mencapai 0.477. Intensitas greenwater terbesar terjadi pada saat sudut datang gelombang following sea (0o adalah sebanyak 59.265 per jam dan 0.378 per detik. Tekanan greenwater terbesar terjadi pada saat sudut datang gelombang head sea (180o sebesar 1678x10-6 MPa. Dengan nilai tersebut, deck mampu menahan beban akibat tekanan greenwater.

A genome-wide association study for equine recurrent airway obstruction in European Warmblood horses reveals a suggestive new quantitative trait locus on chromosome 13.

Science.gov (United States)

Schnider, D; Rieder, S; Leeb, T; Gerber, V; Neuditschko, M

2017-12-01

Recurrent airway obstruction (RAO), also known as heaves, is an asthma-like respiratory disease. Its development is strongly influenced by environmental risk factors such as sensitization and exposure to moldy hay, straw bedding and stabling indoors. A hereditary component has been documented in previous studies; however, so far no causative genetic variant that influences the risk of developing RAO has been identified. In this study, we revised an existing dataset and selected 384 horses for genotyping on the Affymetrix high-density equine SNP array. We performed an allelic case-control genome-wide association study, which revealed a suggestively significant association on equine chromosome 13 at 32 843 309 bp. This SNP is located in the protein-coding gene TXNDC11, which is possibly involved in the folding process of the multiprotein complexes DUOX1 and DUOX2. In humans, these proteins are known to take part in regulating the production of H 2 O 2 in the respiratory tract epithelium as well as in MUC5AC mucin expression. Therefore, TXNDC11 may be considered a functional candidate gene, and further research is needed to explore its potential role in RAO-affected horses. © 2017 Stichting International Foundation for Animal Genetics.

Application of the Most Likely Extreme Response Method for Wave Energy Converters: Preprint

Energy Technology Data Exchange (ETDEWEB)

Quon, Eliot; Platt, Andrew; Yu, Yi-Hsiang; Lawson, Michael

2016-07-01

Extreme loads are often a key cost driver for wave energy converters (WECs). As an alternative to exhaustive Monte Carlo or long-term simulations, the most likely extreme response (MLER) method allows mid- and high-fidelity simulations to be used more efficiently in evaluating WEC response to events at the edges of the design envelope, and is therefore applicable to system design analysis. The study discussed in this paper applies the MLER method to investigate the maximum heave, pitch, and surge force of a point absorber WEC. Most likely extreme waves were obtained from a set of wave statistics data based on spectral analysis and the response amplitude operators (RAOs) of the floating body; the RAOs were computed from a simple radiation-and-diffraction-theory-based numerical model. A weakly nonlinear numerical method and a computational fluid dynamics (CFD) method were then applied to compute the short-term response to the MLER wave. Effects of nonlinear wave and floating body interaction on the WEC under the anticipated 100-year waves were examined by comparing the results from the linearly superimposed RAOs, the weakly nonlinear model, and CFD simulations. Overall, the MLER method was successfully applied. In particular, when coupled to a high-fidelity CFD analysis, the nonlinear fluid dynamics can be readily captured.

Macromolecular Design Strategies for Preventing Active-Material Crossover in Non-Aqueous All-Organic Redox-Flow Batteries.

Science.gov (United States)

Doris, Sean E; Ward, Ashleigh L; Baskin, Artem; Frischmann, Peter D; Gavvalapalli, Nagarjuna; Chénard, Etienne; Sevov, Christo S; Prendergast, David; Moore, Jeffrey S; Helms, Brett A

2017-02-01

Intermittent energy sources, including solar and wind, require scalable, low-cost, multi-hour energy storage solutions in order to be effectively incorporated into the grid. All-Organic non-aqueous redox-flow batteries offer a solution, but suffer from rapid capacity fade and low Coulombic efficiency due to the high permeability of redox-active species across the battery's membrane. Here we show that active-species crossover is arrested by scaling the membrane's pore size to molecular dimensions and in turn increasing the size of the active material above the membrane's pore-size exclusion limit. When oligomeric redox-active organics (RAOs) were paired with microporous polymer membranes, the rate of active-material crossover was reduced more than 9000-fold compared to traditional separators at minimal cost to ionic conductivity. This corresponds to an absolute rate of RAO crossover of less than 3 μmol cm -2  day -1 (for a 1.0 m concentration gradient), which exceeds performance targets recently set forth by the battery industry. This strategy was generalizable to both high and low-potential RAOs in a variety of non-aqueous electrolytes, highlighting the versatility of macromolecular design in implementing next-generation redox-flow batteries. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Non-Book Materials and Copyright.

Science.gov (United States)

McNally, Paul T.

1978-01-01

Reviews Australian copyright laws as they apply to photographs, slides, overhead transparencies, filmstrips, sound and video recordings, and films. Responsibilities of the library as user are discussed. (RAO)

Oke et al (5).cdr

African Journals Online (AJOL)

Timothy Ademakinwa

River Basin using three empirical formulae which include modified Chaturvedi formula, Krishna Rao ... Keywords: Empirical Formulae; Groundwater Recharge; Ogun River Basin; Oshun River Basin, Inter Item ..... Modeling of Groundwater in.

List of Participants

Indian Academy of Sciences (India)

Guna Sundari E, Vellore Institute of Technology ... Linesh J, Government College, Mananthavdy. Linganna K ... Ramachandra Rao K, Government College, Rajamundry ... Kumar N R P, Laser Spectra Services/Newport Corporation, Bangalore.

Holography: Use in Training and Testing Drivers on the Road in Accident Avoidance.

Science.gov (United States)

Frey, Allan H.; Frey, Donnalyn

1979-01-01

Defines holography, identifies visual factors in driving and the techniques used in on-road visual presentations, and presents the design and testing of a holographic system for driver training. (RAO)

Autologous bone marrow mononuclear cell delivery to dilated ...

African Journals Online (AJOL)

Autologous bone marrow mononuclear cell delivery to dilated cardiomyopathy patients: A clinical trial. PLN Kaparthi, G Namita, LK Chelluri, VSP Rao, PK Shah, A Vasantha, SK Ratnakar, K Ravindhranath ...

Factores asociados a la prevalencia de enfermedad por reflujo gastroesofágico en funcionarios de una universidad pública de Ibagué (Colombia

Directory of Open Access Journals (Sweden)

Elizabeth Fajardo Ramos

2017-01-01

Full Text Available Objetivo: Determinar la prevalencia de enfermedad por reflujo gastroesofágico ( ERGE y los factores asociados en una población de funcionarios administrativos de una Universidad Pública del municipio de Ibagué (Colombia. Materiales y métodos: Se realizó un estudio observacional, descriptivo correlacional, con una muestra de 171 funcionarios administrativos, seleccionados mediante muestreo aleatorio estratificado, con edades comprendidas entre 18 y 65 años, durante el segundo semestre de 2016. Se calculó la prevalencia de ERGE ; se utilizó la prueba chi2 para determinar la correlación entre la ERGE y variables independientes; se halló el OR y para las variables estadísticamente significativas se utilizaron las medidas de riesgo atribuible ( FEp y FEe . Resultados: El 58,5 % (100 eran mujeres; la edad promedio fue de 42,5 años ( DE +/- 10,3 años y la moda en el rango de edad fue de 30-39 años; 24,6 % (42 de la población estudiada presentó ERGE ; 57,9 % (99 tenía IMC anormal (>25 kg/m 2 , y 16,4 % (28 tuvo antecedente de tabaquismo. La ERGE se asoció significativamente a IMC anormal (p: 0,016. OR : 2,58 ( IC : 1,171-5,459 y a tabaquismo (p: 0,046, OR : 2,188 ( IC : 1,003-4,771; el riesgo atribuible para estas variables fue: IMC anormal ( FEp : 0,44 y FEe : 0,60 y tabaquismo ( FEp : 0,18 y FEe : 0,54. Conclusiones: El estudio mostró una prevalencia del 24,6 % de ERGE en funcionarios ad - ministrativos, lo cual indica que una cuarta parte de la población está afectada. En cuanto a los factores asociados, el IMC anormal y el tabaquismo fueron los más representativos.

Role of intermetallics on the mechanical fatigue behavior of Cu–Al ball bond interfaces

Energy Technology Data Exchange (ETDEWEB)

Lassnig, A., E-mail: alice.lassnig@univie.ac.at [University of Vienna, Faculty of Physics, Physics of Nanostructured Materials, Boltzmanngasse 5, 1090 Wien (Austria); Pelzer, R. [Infineon Technologies Austria AG, Siemensstrae 2, 9500 Villach (Austria); Gammer, C. [University of Vienna, Faculty of Physics, Physics of Nanostructured Materials, Boltzmanngasse 5, 1090 Wien (Austria); National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Khatibi, G. [Vienna University of Technology, Institute of Chemical Technology and Analytics, Getreidemarkt 9, 1060 Wien (Austria)

2015-10-15

The mechanical fatigue behavior of Cu–Al interfaces occurring in thermosonic ball bonds –typically used in microelectronic packages for automotive applications – is investigated by means of a specially designed fatigue test technique. Fully reversed cyclic shear stresses are induced at the bond interface, leading to subsequent fatigue lift off failure and revealing the weakest site of the bond. A special focus is set on the role of interfacial intermetallic compounds (IMC) on the fatigue performance of such interfaces. Therefore fatigue life curves were obtained for three representative microstructural states: The as-bonded state is compared to two annealed states at 200 °C for 200 h and at 200 °C for 2000 h respectively. In the moderately annealed state two IMC layers (Al{sub 2}Cu, Al{sub 4}Cu{sub 9}) could be identified, whereas in the highly aged state the original pad metallization was almost entirely consumed and AlCu is formed as a third IMC. Finally, the crack path is traced back as a function of interfacial microstructure by means of electron microscopy techniques. Whereas conventional static shear tests reveal no significant decrease of the bond shear force with increased IMC formation the fatigue tests prove a clear degradation in the cyclic mechanical performance. It can be concluded that during cycling the crack deflects easily into the formed intermetallics, leading to early failure of the ball bonds due to their brittle nature. - Highlights: • High cycle fatigue of various miniaturized Cu–Al interfaces is investigated. • Interfacial intermetallic compounds consist of Al2Cu, AlCu and Al4Cu9. • Static shear strength shows minor dependency on interfacial phase formation. • Fatigue tests prove significant degradation with intermetallic compound evolution. • Fatigue fracture surface analysis reveal microstructure dependent crack path.

The Effectiveness of Surface Coatings on Preventing Interfacial Reaction During Ultrasonic Welding of Aluminum to Magnesium

Science.gov (United States)

Panteli, Alexandria; Robson, Joseph D.; Chen, Ying-Chun; Prangnell, Philip B.

2013-12-01

High power ultrasonic spot welding (USW) is a solid-state joining process that is advantageous for welding difficult dissimilar material couples, like magnesium to aluminum. USW is also a useful technique for testing methods of controlling interfacial reaction in welding as the interface is not greatly displaced by the process. However, the high strain rate deformation in USW has been found to accelerate intermetallic compound (IMC) formation and a thick Al12Mg17 and Al3Mg2 reaction layer forms after relatively short welding times. In this work, we have investigated the potential of two approaches for reducing the IMC reaction rate in dissimilar Al-Mg ultrasonic welds, both involving coatings on the Mg sheet surface to (i) separate the join line from the weld interface, using a 100- μm-thick Al cold spray coating, and (ii) provide a diffusion barrier layer, using a thin manganese physical vapor deposition (PVD) coating. Both methods were found to reduce the level of reaction and increase the failure energy of the welds, but their effectiveness was limited due to issues with coating attachment and survivability during the welding cycle. The effect of the coatings on the joint's interface microstructure, and the fracture behavior have been investigated in detail. Kinetic modeling has been used to show that the benefit of the cold spray coating can be attributed to the reaction rate reverting to that expected under static conditions. This reduces the IMC growth rate by over 50 pct because at the weld line, the high strain rate dynamic deformation in USW normally enhances diffusion through the IMC layer. In comparison, the thin PVD barrier coating was found to rapidly break up early in USW and become dispersed throughout the deformation layer reducing its effectiveness.

Role of intermetallics on the mechanical fatigue behavior of Cu–Al ball bond interfaces

International Nuclear Information System (INIS)

Lassnig, A.; Pelzer, R.; Gammer, C.; Khatibi, G.

2015-01-01

The mechanical fatigue behavior of Cu–Al interfaces occurring in thermosonic ball bonds –typically used in microelectronic packages for automotive applications – is investigated by means of a specially designed fatigue test technique. Fully reversed cyclic shear stresses are induced at the bond interface, leading to subsequent fatigue lift off failure and revealing the weakest site of the bond. A special focus is set on the role of interfacial intermetallic compounds (IMC) on the fatigue performance of such interfaces. Therefore fatigue life curves were obtained for three representative microstructural states: The as-bonded state is compared to two annealed states at 200 °C for 200 h and at 200 °C for 2000 h respectively. In the moderately annealed state two IMC layers (Al 2 Cu, Al 4 Cu 9 ) could be identified, whereas in the highly aged state the original pad metallization was almost entirely consumed and AlCu is formed as a third IMC. Finally, the crack path is traced back as a function of interfacial microstructure by means of electron microscopy techniques. Whereas conventional static shear tests reveal no significant decrease of the bond shear force with increased IMC formation the fatigue tests prove a clear degradation in the cyclic mechanical performance. It can be concluded that during cycling the crack deflects easily into the formed intermetallics, leading to early failure of the ball bonds due to their brittle nature. - Highlights: • High cycle fatigue of various miniaturized Cu–Al interfaces is investigated. • Interfacial intermetallic compounds consist of Al2Cu, AlCu and Al4Cu9. • Static shear strength shows minor dependency on interfacial phase formation. • Fatigue tests prove significant degradation with intermetallic compound evolution. • Fatigue fracture surface analysis reveal microstructure dependent crack path